Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= MFBP10_F_C02
(876 letters)
Database: uniref50
1,657,284 sequences; 575,637,011 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
UniRef50_A7T6B8 Cluster: Predicted protein; n=1; Nematostella ve... 139 7e-32
UniRef50_Q4S0L0 Cluster: Malic enzyme; n=2; Tetraodon nigrovirid... 132 8e-30
UniRef50_Q5BX10 Cluster: Malic enzyme; n=1; Schistosoma japonicu... 132 1e-29
UniRef50_Q16798 Cluster: NADP-dependent malic enzyme, mitochondr... 128 2e-28
UniRef50_P23368 Cluster: NAD-dependent malic enzyme, mitochondri... 126 7e-28
UniRef50_P48163 Cluster: NADP-dependent malic enzyme; n=63; Euka... 120 5e-26
UniRef50_P06801 Cluster: NADP-dependent malic enzyme; n=52; cell... 116 8e-25
UniRef50_A0L5P5 Cluster: Malate dehydrogenase (Oxaloacetate-deca... 113 6e-24
UniRef50_Q89G76 Cluster: Malic enzyme; n=3; cellular organisms|R... 110 4e-23
UniRef50_P16243 Cluster: NADP-dependent malic enzyme, chloroplas... 109 1e-22
UniRef50_A2ZQ54 Cluster: Malic enzyme; n=9; Oryza sativa|Rep: Ma... 108 2e-22
UniRef50_P78715 Cluster: Malic enzyme, hydrogenosomal precursor;... 106 6e-22
UniRef50_Q016K2 Cluster: NADP dependent malic enzyme; n=2; Ostre... 106 8e-22
UniRef50_A7IMB8 Cluster: Malate dehydrogenase (Oxaloacetate-deca... 105 2e-21
UniRef50_A7CWP9 Cluster: Malate dehydrogenase (Oxaloacetate-deca... 104 3e-21
UniRef50_A7PC00 Cluster: Chromosome chr2 scaffold_11, whole geno... 96 1e-18
UniRef50_Q8D911 Cluster: NAD-dependent malic enzyme; n=187; cell... 95 2e-18
UniRef50_Q7K3R0 Cluster: Malic enzyme; n=2; Sophophora|Rep: Mali... 95 2e-18
UniRef50_Q875H8 Cluster: Malic enzyme; n=1; Mucor circinelloides... 94 4e-18
UniRef50_Q0AIF8 Cluster: Malate dehydrogenase (Oxaloacetate-deca... 94 5e-18
UniRef50_Q8I8I4 Cluster: Malic enzyme; n=4; Eukaryota|Rep: Malic... 90 6e-17
UniRef50_Q86NT5 Cluster: Malic enzyme; n=2; Drosophila melanogas... 89 1e-16
UniRef50_Q00XN9 Cluster: Malic enzyme; n=2; Ostreococcus|Rep: Ma... 89 2e-16
UniRef50_A1ZAF7 Cluster: Malic enzyme; n=5; Sophophora|Rep: Mali... 88 2e-16
UniRef50_P45868 Cluster: Probable NAD-dependent malic enzyme 2; ... 87 7e-16
UniRef50_Q7SHJ8 Cluster: Malic enzyme; n=12; Pezizomycotina|Rep:... 85 2e-15
UniRef50_A4RQC9 Cluster: Malic enzyme; n=2; Ostreococcus|Rep: Ma... 84 5e-15
UniRef50_A6SA55 Cluster: Malic enzyme; n=2; Sclerotiniaceae|Rep:... 83 9e-15
UniRef50_A0Q531 Cluster: NAD-dependent malic enzyme; n=10; Franc... 83 1e-14
UniRef50_P37221 Cluster: NAD-dependent malic enzyme 62 kDa isofo... 82 2e-14
UniRef50_Q4QAQ6 Cluster: Malic enzyme, putative; n=20; Trypanoso... 81 5e-14
UniRef50_A2QY66 Cluster: Malic enzyme; n=2; cellular organisms|R... 80 6e-14
UniRef50_Q9RYN4 Cluster: Malate oxidoreductase; n=6; Deinococci|... 80 8e-14
UniRef50_A1SVL3 Cluster: Malic enzyme aka malate dehydrogenase (... 80 8e-14
UniRef50_A2EKE3 Cluster: Malic enzyme; n=14; Trichomonadidae|Rep... 78 3e-13
UniRef50_Q4PC56 Cluster: Malic enzyme; n=1; Ustilago maydis|Rep:... 77 6e-13
UniRef50_Q4X1Z2 Cluster: NADP-dependent malic enzyme MaeA; n=11;... 75 2e-12
UniRef50_Q9HE50 Cluster: Malic enzyme; n=6; Pezizomycotina|Rep: ... 75 3e-12
UniRef50_A3QW96 Cluster: Malic enzyme; n=10; Tigriopus californi... 74 6e-12
UniRef50_UPI0000D9F768 Cluster: PREDICTED: similar to Y48B6A.12,... 73 7e-12
UniRef50_Q9S4T5 Cluster: NAD-malate oxidoreductase homolog; n=15... 73 7e-12
UniRef50_Q8Y5Y8 Cluster: Lmo1915 protein; n=15; Firmicutes|Rep: ... 72 2e-11
UniRef50_Q48796 Cluster: Malolactic enzyme; n=49; Bacteria|Rep: ... 71 3e-11
UniRef50_Q5CS07 Cluster: Malic enzyme; n=2; Cryptosporidium|Rep:... 70 9e-11
UniRef50_P40375 Cluster: NAD-dependent malic enzyme; n=3; Schizo... 67 5e-10
UniRef50_Q5KEY3 Cluster: Malic enzyme; n=1; Filobasidiella neofo... 65 3e-09
UniRef50_Q95061 Cluster: Malic enzyme; n=2; Giardia intestinalis... 64 3e-09
UniRef50_Q6AL43 Cluster: Related to NAD-dependent malic enzyme; ... 62 2e-08
UniRef50_P36013 Cluster: NAD-dependent malic enzyme, mitochondri... 61 4e-08
UniRef50_Q2HCG7 Cluster: Malic enzyme; n=1; Chaetomium globosum|... 60 1e-07
UniRef50_Q01AM5 Cluster: NADP+-dependent malic enzyme; n=2; Ostr... 58 2e-07
UniRef50_A6XP71 Cluster: Malic enzyme protein 2; n=2; Mucoromyco... 54 5e-06
UniRef50_Q5KBK5 Cluster: Nad-dependent malic enzyme, putative; n... 51 4e-05
UniRef50_A3BK03 Cluster: Malic enzyme; n=2; Oryza sativa|Rep: Ma... 46 0.001
UniRef50_A4SKB8 Cluster: NAD-dependent malic enzyme; n=2; Aeromo... 44 0.004
UniRef50_Q5K758 Cluster: Malic enzyme; n=1; Filobasidiella neofo... 44 0.004
UniRef50_A3YYQ0 Cluster: Malate oxidoreductase; n=1; Synechococc... 41 0.036
UniRef50_Q97XF3 Cluster: Putative uncharacterized protein; n=1; ... 36 1.8
UniRef50_Q3IFJ8 Cluster: Putative D-cysteine desulfhydrase, PLP-... 35 3.1
UniRef50_Q08PM3 Cluster: Hemin ABC transporter, periplasmic hemi... 34 4.1
UniRef50_A4RZU1 Cluster: Malic enzyme; n=2; Ostreococcus|Rep: Ma... 34 4.1
UniRef50_Q2H899 Cluster: Putative uncharacterized protein; n=1; ... 34 4.1
UniRef50_Q4SHK3 Cluster: Chromosome 5 SCAF14581, whole genome sh... 34 5.5
UniRef50_Q116W6 Cluster: Putative uncharacterized protein; n=1; ... 34 5.5
UniRef50_Q4RNM6 Cluster: Chromosome 21 SCAF15012, whole genome s... 33 7.2
UniRef50_A4XFU6 Cluster: Binding-protein-dependent transport sys... 33 7.2
UniRef50_A6LMP2 Cluster: Diguanylate cyclase; n=1; Thermosipho m... 33 9.5
UniRef50_Q4P7L2 Cluster: Putative uncharacterized protein; n=1; ... 33 9.5
>UniRef50_A7T6B8 Cluster: Predicted protein; n=1; Nematostella
vectensis|Rep: Predicted protein - Nematostella
vectensis
Length = 365
Score = 139 bits (337), Expect = 7e-32
Identities = 63/128 (49%), Positives = 87/128 (67%)
Frame = +1
Query: 493 LSGLDHLKHPGLNKGMAFTIEERQLLGIHGLLPPRVKTQEEQVELCKLSIDRYENPLNKY 672
+ G D ++ LNKG+AFT+EERQ+LGIHGLLPP V +QE Q + + R N L KY
Sbjct: 13 IRGTDIMRDSHLNKGLAFTLEERQILGIHGLLPPCVISQEIQAQRVYRELQRKPNDLEKY 72
Query: 673 IYLMGLLDRNEHLFYRFVADXVADMMPLCTLRRLAWPXQKXXLVYRRPRGLFITIHDKGH 852
I LM LL+RNE LF+R + D ++MP+ + +K +++RRPRGLFI+IHDKGH
Sbjct: 73 IQLMALLERNESLFFRVLFDYTEELMPIVYTPTVGLACRKYGMIFRRPRGLFISIHDKGH 132
Query: 853 VYDVLKNW 876
+ D++ NW
Sbjct: 133 IRDIVSNW 140
>UniRef50_Q4S0L0 Cluster: Malic enzyme; n=2; Tetraodon
nigroviridis|Rep: Malic enzyme - Tetraodon nigroviridis
(Green puffer)
Length = 694
Score = 132 bits (320), Expect = 8e-30
Identities = 65/139 (46%), Positives = 84/139 (60%)
Frame = +1
Query: 460 GAPGXGQPTSGLSGLDHLKHPGLNKGMAFTIEERQLLGIHGLLPPRVKTQEEQVELCKLS 639
G G + G D ++P LNKGMAFT+EER +GIHGLLPP +Q+ QV S
Sbjct: 49 GTASEGSVRTKKRGYDITRNPHLNKGMAFTLEERLQMGIHGLLPPCFLSQDVQVLRVMKS 108
Query: 640 IDRYENPLNKYIYLMGLLDRNEHLFYRFVADXVADMMPLCTLRRLAWPXQKXXLVYRRPR 819
+ NPL+KYI LM L DRNE LFYR + + MP+ + Q+ L +RRPR
Sbjct: 109 YETRSNPLDKYILLMTLQDRNEKLFYRVLTSDIEKFMPIVYTPTVGLACQQYGLAFRRPR 168
Query: 820 GLFITIHDKGHVYDVLKNW 876
GLFITIHD+GH+ +L +W
Sbjct: 169 GLFITIHDRGHIATMLNSW 187
>UniRef50_Q5BX10 Cluster: Malic enzyme; n=1; Schistosoma
japonicum|Rep: Malic enzyme - Schistosoma japonicum
(Blood fluke)
Length = 216
Score = 132 bits (319), Expect = 1e-29
Identities = 62/128 (48%), Positives = 83/128 (64%)
Frame = +1
Query: 493 LSGLDHLKHPGLNKGMAFTIEERQLLGIHGLLPPRVKTQEEQVELCKLSIDRYENPLNKY 672
L G+D ++ P N+G AFT+ ERQLLGIHGLLPP V T E+QV ++ + L +Y
Sbjct: 52 LLGIDVVRDPRTNRGTAFTVNERQLLGIHGLLPPSVLTLEQQVSKMLANLKNMNDNLQRY 111
Query: 673 IYLMGLLDRNEHLFYRFVADXVADMMPLCTLRRLAWPXQKXXLVYRRPRGLFITIHDKGH 852
IYL L DRNE LFY+ V + V MPL + Q+ +V+RRPRGL+ITIHD+ H
Sbjct: 112 IYLTSLQDRNEALFYKLVIEHVEYCMPLIYTPTVGLACQRYGVVFRRPRGLYITIHDRHH 171
Query: 853 VYDVLKNW 876
+ ++L NW
Sbjct: 172 IPEILNNW 179
>UniRef50_Q16798 Cluster: NADP-dependent malic enzyme, mitochondrial
precursor; n=15; Bilateria|Rep: NADP-dependent malic
enzyme, mitochondrial precursor - Homo sapiens (Human)
Length = 604
Score = 128 bits (308), Expect = 2e-28
Identities = 65/141 (46%), Positives = 85/141 (60%), Gaps = 1/141 (0%)
Frame = +1
Query: 457 YGAPGXGQPTS-GLSGLDHLKHPGLNKGMAFTIEERQLLGIHGLLPPRVKTQEEQVELCK 633
+ PG +P G D ++P LNKGMAFT+EER LGIHGL+PP +Q+ Q+
Sbjct: 35 HSKPGPARPVPLKKRGYDVTRNPHLNKGMAFTLEERLQLGIHGLIPPCFLSQDVQLLRIM 94
Query: 634 LSIDRYENPLNKYIYLMGLLDRNEHLFYRFVADXVADMMPLCTLRRLAWPXQKXXLVYRR 813
+R ++ L+KYI LM L DRNE LFYR + V MP+ + Q L +RR
Sbjct: 95 RYYERQQSDLDKYIILMTLQDRNEKLFYRVLTSDVEKFMPIVYTPTVGLACQHYGLTFRR 154
Query: 814 PRGLFITIHDKGHVYDVLKNW 876
PRGLFITIHDKGH+ +L +W
Sbjct: 155 PRGLFITIHDKGHLATMLNSW 175
>UniRef50_P23368 Cluster: NAD-dependent malic enzyme, mitochondrial
precursor; n=53; Eumetazoa|Rep: NAD-dependent malic
enzyme, mitochondrial precursor - Homo sapiens (Human)
Length = 584
Score = 126 bits (304), Expect = 7e-28
Identities = 53/120 (44%), Positives = 82/120 (68%)
Frame = +1
Query: 517 HPGLNKGMAFTIEERQLLGIHGLLPPRVKTQEEQVELCKLSIDRYENPLNKYIYLMGLLD 696
+P NKGMAFT++ERQ+LG+ GLLPP+++TQ+ Q ++ + +PL KYIY+MG+ +
Sbjct: 31 NPRTNKGMAFTLQERQMLGLQGLLPPKIETQDIQALRFHRNLKKMTSPLEKYIYIMGIQE 90
Query: 697 RNEHLFYRFVADXVADMMPLCTLRRLAWPXQKXXLVYRRPRGLFITIHDKGHVYDVLKNW 876
RNE LFYR + D + +MP+ + + ++RRP+GLFI+I D+GHV ++ NW
Sbjct: 91 RNEKLFYRILQDDIESLMPIVYTPTVGLACSQYGHIFRRPKGLFISISDRGHVRSIVDNW 150
>UniRef50_P48163 Cluster: NADP-dependent malic enzyme; n=63;
Eukaryota|Rep: NADP-dependent malic enzyme - Homo
sapiens (Human)
Length = 572
Score = 120 bits (289), Expect = 5e-26
Identities = 56/121 (46%), Positives = 76/121 (62%)
Frame = +1
Query: 514 KHPGLNKGMAFTIEERQLLGIHGLLPPRVKTQEEQVELCKLSIDRYENPLNKYIYLMGLL 693
++P LNK +AFT+EERQ L IHGLLPP +QE QV + + + ++Y+ LM L
Sbjct: 20 RNPHLNKDLAFTLEERQQLNIHGLLPPSFNSQEIQVLRVVKNFEHLNSDFDRYLLLMDLQ 79
Query: 694 DRNEHLFYRFVADXVADMMPLCTLRRLAWPXQKXXLVYRRPRGLFITIHDKGHVYDVLKN 873
DRNE LFYR + + MP+ + Q+ LV+R+PRGLFITIHD+GH+ VL
Sbjct: 80 DRNEKLFYRVLTSDIEKFMPIVYTPTVGLACQQYSLVFRKPRGLFITIHDRGHIASVLNA 139
Query: 874 W 876
W
Sbjct: 140 W 140
>UniRef50_P06801 Cluster: NADP-dependent malic enzyme; n=52;
cellular organisms|Rep: NADP-dependent malic enzyme -
Mus musculus (Mouse)
Length = 572
Score = 116 bits (279), Expect = 8e-25
Identities = 56/121 (46%), Positives = 75/121 (61%)
Frame = +1
Query: 514 KHPGLNKGMAFTIEERQLLGIHGLLPPRVKTQEEQVELCKLSIDRYENPLNKYIYLMGLL 693
+ P LNK +AFT+EERQ L IHGLLPP + +QE QV + +R + ++Y+ LM L
Sbjct: 20 RDPHLNKDLAFTLEERQQLNIHGLLPPCIISQELQVLRIIKNFERLNSDFDRYLLLMDLQ 79
Query: 694 DRNEHLFYRFVADXVADMMPLCTLRRLAWPXQKXXLVYRRPRGLFITIHDKGHVYDVLKN 873
DRNE LFY + V MP+ + Q+ L +R+PRGLFI+IHDKGH+ VL
Sbjct: 80 DRNEKLFYSVLMSDVEKFMPIVYTPTVGLACQQYSLAFRKPRGLFISIHDKGHIASVLNA 139
Query: 874 W 876
W
Sbjct: 140 W 140
>UniRef50_A0L5P5 Cluster: Malate dehydrogenase
(Oxaloacetate-decarboxylating) (NADP(+)); n=1;
Magnetococcus sp. MC-1|Rep: Malate dehydrogenase
(Oxaloacetate-decarboxylating) (NADP(+)) - Magnetococcus
sp. (strain MC-1)
Length = 556
Score = 113 bits (272), Expect = 6e-24
Identities = 56/131 (42%), Positives = 80/131 (61%)
Frame = +1
Query: 484 TSGLSGLDHLKHPGLNKGMAFTIEERQLLGIHGLLPPRVKTQEEQVELCKLSIDRYENPL 663
T + L+ L P +NKG+AFT EER L + GLLPPRV+T E Q+ + N L
Sbjct: 14 TGHANPLEILNDPYMNKGVAFTEEERDLFHLRGLLPPRVQTMEAQLGRALDNFRCKPNDL 73
Query: 664 NKYIYLMGLLDRNEHLFYRFVADXVADMMPLCTLRRLAWPXQKXXLVYRRPRGLFITIHD 843
KYI+L GL +RNE LFYR V + +M+P+ + Q ++RRP+G+FI+I+D
Sbjct: 74 EKYIFLTGLQERNETLFYRLVMTNIEEMLPIIYTPTVGKACQTYGHIFRRPQGMFISIND 133
Query: 844 KGHVYDVLKNW 876
KG + ++L NW
Sbjct: 134 KGRIAELLGNW 144
>UniRef50_Q89G76 Cluster: Malic enzyme; n=3; cellular organisms|Rep:
Malic enzyme - Bradyrhizobium japonicum
Length = 531
Score = 110 bits (265), Expect = 4e-23
Identities = 53/122 (43%), Positives = 74/122 (60%)
Frame = +1
Query: 511 LKHPGLNKGMAFTIEERQLLGIHGLLPPRVKTQEEQVELCKLSIDRYENPLNKYIYLMGL 690
L+ P LNKG AFT ER LG+ GLLPP V T E QV+ ++ L KY+ L L
Sbjct: 4 LRDPLLNKGTAFTEAERAALGLRGLLPPCVLTMETQVDRVLTNLRMLPTDLEKYVALNAL 63
Query: 691 LDRNEHLFYRFVADXVADMMPLCTLRRLAWPXQKXXLVYRRPRGLFITIHDKGHVYDVLK 870
DRNE LF+R V D + ++ P+ + QK L+++RPRG+FI+ D+G + ++LK
Sbjct: 64 HDRNEALFFRVVVDNIDEIQPIIYTPTVGLACQKYGLIFQRPRGMFISSRDRGQIAEILK 123
Query: 871 NW 876
NW
Sbjct: 124 NW 125
>UniRef50_P16243 Cluster: NADP-dependent malic enzyme, chloroplast
precursor; n=79; Magnoliophyta|Rep: NADP-dependent malic
enzyme, chloroplast precursor - Zea mays (Maize)
Length = 636
Score = 109 bits (261), Expect = 1e-22
Identities = 52/131 (39%), Positives = 81/131 (61%)
Frame = +1
Query: 484 TSGLSGLDHLKHPGLNKGMAFTIEERQLLGIHGLLPPRVKTQEEQVELCKLSIDRYENPL 663
TS SG L+ P NKG+AFT EER + GLLPP V +QE Q++ ++ +Y+ PL
Sbjct: 92 TSVASGYTLLRDPHHNKGLAFTEEERDGHYLRGLLPPAVLSQELQIKKFMNTLRQYQTPL 151
Query: 664 NKYIYLMGLLDRNEHLFYRFVADXVADMMPLCTLRRLAWPXQKXXLVYRRPRGLFITIHD 843
+YI +M L + +E LFY+ + D V +++P + QK ++ RP+GL++++ D
Sbjct: 152 QRYIAMMNLQETDERLFYKLLIDNVVELLPFVYTPTVGEACQKYGSIFGRPQGLYVSLKD 211
Query: 844 KGHVYDVLKNW 876
KG V +VL+NW
Sbjct: 212 KGKVLEVLRNW 222
>UniRef50_A2ZQ54 Cluster: Malic enzyme; n=9; Oryza sativa|Rep: Malic
enzyme - Oryza sativa subsp. japonica (Rice)
Length = 613
Score = 108 bits (259), Expect = 2e-22
Identities = 50/127 (39%), Positives = 81/127 (63%)
Frame = +1
Query: 496 SGLDHLKHPGLNKGMAFTIEERQLLGIHGLLPPRVKTQEEQVELCKLSIDRYENPLNKYI 675
SG L+ P NKG+AF+ +ER + GLLPP V +Q+ QV+ ++ +Y PL +Y+
Sbjct: 99 SGYTLLRDPHHNKGLAFSEKERDAHYLRGLLPPAVVSQDLQVKKIMHNLRQYSVPLQRYM 158
Query: 676 YLMGLLDRNEHLFYRFVADXVADMMPLCTLRRLAWPXQKXXLVYRRPRGLFITIHDKGHV 855
+M L +RNE LFY+ + D V +++P+ + QK ++R+P+GL++++ DKG V
Sbjct: 159 AMMDLQERNERLFYKLLIDNVEELLPVVYTPTVGEACQKYGSIFRQPQGLYVSLKDKGKV 218
Query: 856 YDVLKNW 876
DVL+NW
Sbjct: 219 LDVLRNW 225
>UniRef50_P78715 Cluster: Malic enzyme, hydrogenosomal precursor;
n=1; Neocallimastix frontalis|Rep: Malic enzyme,
hydrogenosomal precursor - Neocallimastix frontalis
(Rumen fungus)
Length = 592
Score = 106 bits (255), Expect = 6e-22
Identities = 48/127 (37%), Positives = 77/127 (60%)
Frame = +1
Query: 496 SGLDHLKHPGLNKGMAFTIEERQLLGIHGLLPPRVKTQEEQVELCKLSIDRYENPLNKYI 675
+GLD L P LNKG AFT +E+ LGI GL+PPR ++ E Q + CK ++D+ +PL K+I
Sbjct: 46 TGLDILNDPKLNKGSAFTADEKDRLGIRGLVPPRPQSLEAQYKRCKTNLDKISDPLEKFI 105
Query: 676 YLMGLLDRNEHLFYRFVADXVADMMPLCTLRRLAWPXQKXXLVYRRPRGLFITIHDKGHV 855
YL L +RNE L+Y+ + + ++ P+ + QK ++ + RG++ + D+G +
Sbjct: 106 YLNHLQNRNETLYYKMILENFVELAPIIYTPVVGEACQKFHKIFTQTRGMYFSTADRGQM 165
Query: 856 YDVLKNW 876
V NW
Sbjct: 166 SAVAANW 172
>UniRef50_Q016K2 Cluster: NADP dependent malic enzyme; n=2;
Ostreococcus|Rep: NADP dependent malic enzyme -
Ostreococcus tauri
Length = 641
Score = 106 bits (254), Expect = 8e-22
Identities = 56/143 (39%), Positives = 85/143 (59%), Gaps = 2/143 (1%)
Frame = +1
Query: 454 DYGAPGXGQPTSG--LSGLDHLKHPGLNKGMAFTIEERQLLGIHGLLPPRVKTQEEQVEL 627
D GAP P + +SG++ L+ NKGM+F +ER L + GLLPP V Q QVE
Sbjct: 66 DDGAPRTMVPWNRTVISGVELLRSGRYNKGMSFARDERDRLNLRGLLPPAVFDQATQVER 125
Query: 628 CKLSIDRYENPLNKYIYLMGLLDRNEHLFYRFVADXVADMMPLCTLRRLAWPXQKXXLVY 807
+ R + + K+ +L L +RNE LFYR V D + +++P+ + ++ L+Y
Sbjct: 126 VIERLRRVTSGVEKHAWLPALYERNERLFYRVVKDHLEELLPVLAEPTVWQVCREAGLMY 185
Query: 808 RRPRGLFITIHDKGHVYDVLKNW 876
R+PRGL++++ DKG VY +LKNW
Sbjct: 186 RQPRGLYVSMQDKGSVYRLLKNW 208
>UniRef50_A7IMB8 Cluster: Malate dehydrogenase
(Oxaloacetate-decarboxylating) (NADP(+)); n=2;
Alphaproteobacteria|Rep: Malate dehydrogenase
(Oxaloacetate-decarboxylating) (NADP(+)) - Xanthobacter
sp. (strain Py2)
Length = 550
Score = 105 bits (251), Expect = 2e-21
Identities = 55/132 (41%), Positives = 80/132 (60%)
Frame = +1
Query: 481 PTSGLSGLDHLKHPGLNKGMAFTIEERQLLGIHGLLPPRVKTQEEQVELCKLSIDRYENP 660
P S LSGL+ L P NKG A+T ++R+ LG+ GLLP V+T + QVE +D ++
Sbjct: 13 PKSNLSGLNLLHDPVRNKGTAYTRDDRRQLGLEGLLPHAVETLDRQVERVLDHLDHVKDE 72
Query: 661 LNKYIYLMGLLDRNEHLFYRFVADXVADMMPLCTLRRLAWPXQKXXLVYRRPRGLFITIH 840
L++Y YLM L RNE +FY+ V +P+ +A + +YRRPRG++IT H
Sbjct: 73 LDQYSYLMDLEARNETVFYKAVMSDPKRFIPILYDPTVADACEAFGNLYRRPRGMYITRH 132
Query: 841 DKGHVYDVLKNW 876
KG + +VL+NW
Sbjct: 133 MKGRMAEVLRNW 144
>UniRef50_A7CWP9 Cluster: Malate dehydrogenase
(Oxaloacetate-decarboxylating) (NADP(+)); n=1;
Opitutaceae bacterium TAV2|Rep: Malate dehydrogenase
(Oxaloacetate-decarboxylating) (NADP(+)) - Opitutaceae
bacterium TAV2
Length = 561
Score = 104 bits (249), Expect = 3e-21
Identities = 57/143 (39%), Positives = 80/143 (55%)
Frame = +1
Query: 448 VSDYGAPGXGQPTSGLSGLDHLKHPGLNKGMAFTIEERQLLGIHGLLPPRVKTQEEQVEL 627
VS G G S L G L LNKG AF+ ER LG+ GLLPPRV T E+Q +
Sbjct: 8 VSSLGLSARGARAS-LRGTALLGDSVLNKGTAFSERERDALGLRGLLPPRVFTLEQQEQR 66
Query: 628 CKLSIDRYENPLNKYIYLMGLLDRNEHLFYRFVADXVADMMPLCTLRRLAWPXQKXXLVY 807
++ + + + KYIYL L RNE LFYR + + +M+PL + + +
Sbjct: 67 ALNAMAKKPSAIEKYIYLTTLQSRNETLFYRLLTNHAEEMIPLVYTPTVGQACLEYGANF 126
Query: 808 RRPRGLFITIHDKGHVYDVLKNW 876
RRPRGLFI+I D+G + ++L++W
Sbjct: 127 RRPRGLFISIKDRGRIAEILRHW 149
>UniRef50_A7PC00 Cluster: Chromosome chr2 scaffold_11, whole genome
shotgun sequence; n=3; Vitis vinifera|Rep: Chromosome
chr2 scaffold_11, whole genome shotgun sequence - Vitis
vinifera (Grape)
Length = 573
Score = 95.9 bits (228), Expect = 1e-18
Identities = 47/127 (37%), Positives = 74/127 (58%)
Frame = +1
Query: 496 SGLDHLKHPGLNKGMAFTIEERQLLGIHGLLPPRVKTQEEQVELCKLSIDRYENPLNKYI 675
SG L+ P NKG+AFT +ER + GLLPP V Q+ Q + ++ +Y+ PL +Y+
Sbjct: 196 SGYTLLRDPHHNKGLAFTEKERDAHYLRGLLPPAVLNQDLQEKRLMHNLRQYKVPLQRYM 255
Query: 676 YLMGLLDRNEHLFYRFVADXVADMMPLCTLRRLAWPXQKXXLVYRRPRGLFITIHDKGHV 855
+M +RNE LFY+ + D V +++P+ + QK ++RRP+ L+I G +
Sbjct: 256 AMMDFQERNERLFYKLLIDNVEELLPVVYTPTVGEACQKYGSIFRRPQSLYIIDFFMGKI 315
Query: 856 YDVLKNW 876
+VLKNW
Sbjct: 316 LEVLKNW 322
>UniRef50_Q8D911 Cluster: NAD-dependent malic enzyme; n=187;
cellular organisms|Rep: NAD-dependent malic enzyme -
Vibrio vulnificus
Length = 562
Score = 95.5 bits (227), Expect = 2e-18
Identities = 46/121 (38%), Positives = 70/121 (57%)
Frame = +1
Query: 511 LKHPGLNKGMAFTIEERQLLGIHGLLPPRVKTQEEQVELCKLSIDRYENPLNKYIYLMGL 690
L P LNKG AF+ EER + GLLP +T +EQVE + +E+ ++K+IYL +
Sbjct: 18 LSTPLLNKGSAFSAEERISFNLEGLLPETTETIQEQVERAYMQYKAFESDMDKHIYLRNI 77
Query: 691 LDRNEHLFYRFVADXVADMMPLCTLRRLAWPXQKXXLVYRRPRGLFITIHDKGHVYDVLK 870
D NE LFYR V + + +MMP+ + + +YRR RGLF++ ++ + D+L
Sbjct: 78 QDTNETLFYRLVQNHITEMMPIIYTPTVGAACENFSNIYRRGRGLFVSYANRDRIDDILN 137
Query: 871 N 873
N
Sbjct: 138 N 138
>UniRef50_Q7K3R0 Cluster: Malic enzyme; n=2; Sophophora|Rep: Malic
enzyme - Drosophila melanogaster (Fruit fly)
Length = 633
Score = 95.1 bits (226), Expect = 2e-18
Identities = 48/130 (36%), Positives = 70/130 (53%)
Frame = +1
Query: 487 SGLSGLDHLKHPGLNKGMAFTIEERQLLGIHGLLPPRVKTQEEQVELCKLSIDRYENPLN 666
S + GL L NKG+AFT+ ER++L IHGLLP V+T +EQ E+C ++ + N +
Sbjct: 68 SKVDGLWMLNQSNYNKGLAFTLNERRVLSIHGLLPVAVRTIDEQAEICSNLLESFTNNVQ 127
Query: 667 KYIYLMGLLDRNEHLFYRFVADXVADMMPLCTLRRLAWPXQKXXLVYRRPRGLFITIHDK 846
+YIYL L RN LFY + +P+ +++ +GL+I I D
Sbjct: 128 QYIYLTYLSRRNRRLFYYLLLSNPDRFVPMTDASGSIDLLMVHRMIHSMGQGLYICIKDL 187
Query: 847 GHVYDVLKNW 876
GHV +L NW
Sbjct: 188 GHVSQILSNW 197
>UniRef50_Q875H8 Cluster: Malic enzyme; n=1; Mucor
circinelloides|Rep: Malic enzyme - Mucor circinelloides
Length = 617
Score = 94.3 bits (224), Expect = 4e-18
Identities = 43/126 (34%), Positives = 75/126 (59%)
Frame = +1
Query: 499 GLDHLKHPGLNKGMAFTIEERQLLGIHGLLPPRVKTQEEQVELCKLSIDRYENPLNKYIY 678
G++ L P L+KG AF+I ER+ L I GL+PPR + ++Q+ K ++D E PL K+++
Sbjct: 50 GVNLLHDPLLSKGTAFSIAERERLSIRGLVPPRCQEMDKQLLRIKRNLDACETPLAKFVF 109
Query: 679 LMGLLDRNEHLFYRFVADXVADMMPLCTLRRLAWPXQKXXLVYRRPRGLFITIHDKGHVY 858
L L DRNE L+Y+ + + + ++ + + Q +YRR RG++ + D+G +
Sbjct: 110 LAALHDRNETLYYKIIMEHLEELAGIIYTPTVGLASQMSHSIYRRSRGMYFSSQDRGQMS 169
Query: 859 DVLKNW 876
++ NW
Sbjct: 170 AMVYNW 175
>UniRef50_Q0AIF8 Cluster: Malate dehydrogenase
(Oxaloacetate-decarboxylating) (NADP(+)); n=2;
Nitrosomonas|Rep: Malate dehydrogenase
(Oxaloacetate-decarboxylating) (NADP(+)) - Nitrosomonas
eutropha (strain C71)
Length = 536
Score = 93.9 bits (223), Expect = 5e-18
Identities = 48/128 (37%), Positives = 71/128 (55%)
Frame = +1
Query: 493 LSGLDHLKHPGLNKGMAFTIEERQLLGIHGLLPPRVKTQEEQVELCKLSIDRYENPLNKY 672
L G L P NK AFT EER+ G+ GLLP V ++Q + ++ + + KY
Sbjct: 4 LYGKTLLNDPVQNKSTAFTREEREHYGLQGLLPYGVTDIKKQQQRVLANLRNKSSNIEKY 63
Query: 673 IYLMGLLDRNEHLFYRFVADXVADMMPLCTLRRLAWPXQKXXLVYRRPRGLFITIHDKGH 852
IYL LL+RN+ LFYR + D + ++MPL + K ++R+P+G +IT D+G
Sbjct: 64 IYLNDLLERNQQLFYRTLVDHIGEIMPLVYTPTVGEACVKLSHIFRKPQGFYITPEDRGE 123
Query: 853 VYDVLKNW 876
+ LKNW
Sbjct: 124 IISRLKNW 131
>UniRef50_Q8I8I4 Cluster: Malic enzyme; n=4; Eukaryota|Rep: Malic
enzyme - Mastigamoeba balamuthi (Phreatamoeba balamuthi)
Length = 568
Score = 90.2 bits (214), Expect = 6e-17
Identities = 52/133 (39%), Positives = 68/133 (51%)
Frame = +1
Query: 478 QPTSGLSGLDHLKHPGLNKGMAFTIEERQLLGIHGLLPPRVKTQEEQVELCKLSIDRYEN 657
+P GL+G L G AFT EER+ L I GLLP V+T E Q +
Sbjct: 30 RPADGLAGPSWLTLAPT--GTAFTTEERKALRIRGLLPHAVETIEAQAARAYAQLTSQPT 87
Query: 658 PLNKYIYLMGLLDRNEHLFYRFVADXVADMMPLCTLRRLAWPXQKXXLVYRRPRGLFITI 837
PL KY+YL L RN+ LF+ V V + +PL + K +R P GL+IT
Sbjct: 88 PLLKYLYLSQLSQRNQTLFFYLVQHHVEECVPLVYTPTVGEGCTKFSAEFRNPTGLYITP 147
Query: 838 HDKGHVYDVLKNW 876
DKGHV ++L+NW
Sbjct: 148 EDKGHVAEILENW 160
>UniRef50_Q86NT5 Cluster: Malic enzyme; n=2; Drosophila
melanogaster|Rep: Malic enzyme - Drosophila melanogaster
(Fruit fly)
Length = 610
Score = 89.4 bits (212), Expect = 1e-16
Identities = 42/116 (36%), Positives = 68/116 (58%)
Frame = +1
Query: 529 NKGMAFTIEERQLLGIHGLLPPRVKTQEEQVELCKLSIDRYENPLNKYIYLMGLLDRNEH 708
NK +AFT+EERQ L IHGL+P V+T +EQ+ + + +E+ + +Y YL L E
Sbjct: 56 NKALAFTLEERQRLCIHGLMPACVRTYDEQMLAIESNFHSFESNVGRYRYLRALRQGYER 115
Query: 709 LFYRFVADXVADMMPLCTLRRLAWPXQKXXLVYRRPRGLFITIHDKGHVYDVLKNW 876
L+++FV+ V ++P+ + ++YR G+ IT HD+GH+ +L NW
Sbjct: 116 LYFQFVSKNVHAVLPIIYTPTVGLACTVYGMLYRGMTGIHITKHDRGHMKQILSNW 171
>UniRef50_Q00XN9 Cluster: Malic enzyme; n=2; Ostreococcus|Rep: Malic
enzyme - Ostreococcus tauri
Length = 639
Score = 88.6 bits (210), Expect = 2e-16
Identities = 43/126 (34%), Positives = 68/126 (53%)
Frame = +1
Query: 499 GLDHLKHPGLNKGMAFTIEERQLLGIHGLLPPRVKTQEEQVELCKLSIDRYENPLNKYIY 678
G++ L +P NKG +FT ER+ LG+ GL+PPR +Q E PL+K+ +
Sbjct: 81 GIEVLHNPVYNKGTSFTASERERLGVRGLVPPRFFPIGQQATKIWAQNQSLERPLDKWQH 140
Query: 679 LMGLLDRNEHLFYRFVADXVADMMPLCTLRRLAWPXQKXXLVYRRPRGLFITIHDKGHVY 858
L L DRNE LFYR V D + ++ P+ + + RR RG++ ++ D+G +
Sbjct: 141 LQDLKDRNETLFYRLVHDHIEELAPIIYTPTVGDACLNFSKLLRRARGMYFSVDDRGDIN 200
Query: 859 DVLKNW 876
++ NW
Sbjct: 201 SMMFNW 206
>UniRef50_A1ZAF7 Cluster: Malic enzyme; n=5; Sophophora|Rep: Malic
enzyme - Drosophila melanogaster (Fruit fly)
Length = 603
Score = 88.2 bits (209), Expect = 2e-16
Identities = 39/116 (33%), Positives = 68/116 (58%)
Frame = +1
Query: 529 NKGMAFTIEERQLLGIHGLLPPRVKTQEEQVELCKLSIDRYENPLNKYIYLMGLLDRNEH 708
NKG+AFTI+ERQ LGI GL+P V++ ++Q+ + + + ++ YL + R+
Sbjct: 48 NKGLAFTIKERQRLGIMGLMPCSVRSMDDQMNAALANFEARPTDIARFTYLSAVHHRHRR 107
Query: 709 LFYRFVADXVADMMPLCTLRRLAWPXQKXXLVYRRPRGLFITIHDKGHVYDVLKNW 876
L+YRF+ + + +P+ + L +++ LFI+IHDKGH+ D++ NW
Sbjct: 108 LYYRFIKENIEKSLPIVYTPTVGDVVATYGLNFQQAISLFISIHDKGHIRDLMHNW 163
>UniRef50_P45868 Cluster: Probable NAD-dependent malic enzyme 2;
n=37; Bacteria|Rep: Probable NAD-dependent malic enzyme
2 - Bacillus subtilis
Length = 582
Score = 86.6 bits (205), Expect = 7e-16
Identities = 44/133 (33%), Positives = 75/133 (56%)
Frame = +1
Query: 475 GQPTSGLSGLDHLKHPGLNKGMAFTIEERQLLGIHGLLPPRVKTQEEQVELCKLSIDRYE 654
G + L G + L P LNKG+AF++EERQ LG+ GLLPP V + ++Q +
Sbjct: 27 GHLETTLRGKEVLSIPTLNKGVAFSLEERQELGLEGLLPPTVLSLDQQAQRAYEQFQAQP 86
Query: 655 NPLNKYIYLMGLLDRNEHLFYRFVADXVADMMPLCTLRRLAWPXQKXXLVYRRPRGLFIT 834
+ L + +YL L +RNE LFY+ + + + +M+P+ + Q+ YRRP+G++++
Sbjct: 87 DRLRQNVYLSDLANRNEVLFYKLLKNHLREMLPVVYTPTVGEAIQEYSHEYRRPQGIYLS 146
Query: 835 IHDKGHVYDVLKN 873
I + + +N
Sbjct: 147 IDNIDGIEKAFEN 159
>UniRef50_Q7SHJ8 Cluster: Malic enzyme; n=12; Pezizomycotina|Rep:
Malic enzyme - Neurospora crassa
Length = 611
Score = 85.4 bits (202), Expect = 2e-15
Identities = 45/128 (35%), Positives = 67/128 (52%)
Frame = +1
Query: 493 LSGLDHLKHPGLNKGMAFTIEERQLLGIHGLLPPRVKTQEEQVELCKLSIDRYENPLNKY 672
L G L HP NKG AFT EER+ +HGLLPP++++ E+QV+ N L K
Sbjct: 33 LKGTVLLNHPYFNKGSAFTKEERRDFALHGLLPPQIQSLEQQVQRAYEQYCSQPNDLAKN 92
Query: 673 IYLMGLLDRNEHLFYRFVADXVADMMPLCTLRRLAWPXQKXXLVYRRPRGLFITIHDKGH 852
++ + ++NE LFYR + D + +M + Q ++RRP G+F+ I+D
Sbjct: 93 TFMTSMKEQNEVLFYRLLHDHLDEMFSVVYTPTEGEAIQNYSRLFRRPEGVFLNINDMDS 152
Query: 853 VYDVLKNW 876
V L W
Sbjct: 153 VKRDLAQW 160
>UniRef50_A4RQC9 Cluster: Malic enzyme; n=2; Ostreococcus|Rep: Malic
enzyme - Ostreococcus lucimarinus CCE9901
Length = 549
Score = 83.8 bits (198), Expect = 5e-15
Identities = 42/122 (34%), Positives = 66/122 (54%)
Frame = +1
Query: 511 LKHPGLNKGMAFTIEERQLLGIHGLLPPRVKTQEEQVELCKLSIDRYENPLNKYIYLMGL 690
L P LNKG FT +R+ LG+ GLLP + +T E QV+ + +E +N+YI+L L
Sbjct: 13 LDSPSLNKGTGFTFTQRERLGLRGLLPRKYETVEIQVKRAWTQLCAFEEDMNRYIFLENL 72
Query: 691 LDRNEHLFYRFVADXVADMMPLCTLRRLAWPXQKXXLVYRRPRGLFITIHDKGHVYDVLK 870
+NE LFYR + + + D+MP+ + +YR G++ + D G + +L
Sbjct: 73 HMQNERLFYRVLVEHLEDLMPIVYTPTVGEACINFDALYRNRCGMYFSRLDSGVMRRMLD 132
Query: 871 NW 876
NW
Sbjct: 133 NW 134
>UniRef50_A6SA55 Cluster: Malic enzyme; n=2; Sclerotiniaceae|Rep:
Malic enzyme - Botryotinia fuckeliana B05.10
Length = 685
Score = 83.0 bits (196), Expect = 9e-15
Identities = 40/120 (33%), Positives = 68/120 (56%)
Frame = +1
Query: 517 HPGLNKGMAFTIEERQLLGIHGLLPPRVKTQEEQVELCKLSIDRYENPLNKYIYLMGLLD 696
HP L + +IE R+ GL+PP V++ + Q C ++ + P+ KY+YL L +
Sbjct: 97 HPIL-PDTSHSIELRRKNKTLGLVPPNVESHKLQTTRCLQQLNAKKTPIEKYMYLSNLRN 155
Query: 697 RNEHLFYRFVADXVADMMPLCTLRRLAWPXQKXXLVYRRPRGLFITIHDKGHVYDVLKNW 876
N HLFYR V + + D+ PL + + +Y++P GL+++ HD+G++ +VL NW
Sbjct: 156 NNVHLFYRLVQEHLTDITPLIYTPTVGEACLRWSEIYQQPEGLYLSYHDRGNLEEVLGNW 215
>UniRef50_A0Q531 Cluster: NAD-dependent malic enzyme; n=10;
Francisella tularensis|Rep: NAD-dependent malic enzyme -
Francisella tularensis subsp. novicida (strain U112)
Length = 604
Score = 82.6 bits (195), Expect = 1e-14
Identities = 45/130 (34%), Positives = 71/130 (54%)
Frame = +1
Query: 487 SGLSGLDHLKHPGLNKGMAFTIEERQLLGIHGLLPPRVKTQEEQVELCKLSIDRYENPLN 666
+ L+G L + LNK +AF+ EER + G LP +V++ EEQ + +D N L
Sbjct: 23 TNLTGRQLLNNRVLNKDVAFSQEERIAFDLIGYLPEKVESLEEQAIRVRRQLDLKPNSLE 82
Query: 667 KYIYLMGLLDRNEHLFYRFVADXVADMMPLCTLRRLAWPXQKXXLVYRRPRGLFITIHDK 846
KY++L L D N LFY FV + + ++MP+ + QK +R+ GLFI+I K
Sbjct: 83 KYVFLNRLHDLNTTLFYHFVRENLEEIMPIIYTPTVGEAVQKYSSSFRKQSGLFISISHK 142
Query: 847 GHVYDVLKNW 876
H+ +L+ +
Sbjct: 143 KHIARILERY 152
>UniRef50_P37221 Cluster: NAD-dependent malic enzyme 62 kDa isoform,
mitochondrial precursor; n=41; Eukaryota|Rep:
NAD-dependent malic enzyme 62 kDa isoform, mitochondrial
precursor - Solanum tuberosum (Potato)
Length = 626
Score = 82.2 bits (194), Expect = 2e-14
Identities = 45/135 (33%), Positives = 72/135 (53%), Gaps = 10/135 (7%)
Frame = +1
Query: 502 LDHLKHPGLNKGMAFTIEERQLLGIHGLLPPRVKTQEEQV-----ELCKLSIDRYENPLN 666
LD L P NKG AF+ ER L I GLLPP V + E+Q+ +L +L + + P +
Sbjct: 50 LDILHDPWFNKGTAFSFTERDRLHIRGLLPPNVMSFEQQIARFMADLKRLEVQARDGPSD 109
Query: 667 KYIY-----LMGLLDRNEHLFYRFVADXVADMMPLCTLRRLAWPXQKXXLVYRRPRGLFI 831
Y+ L L DRNE L+Y+ + + + + P+ + QK ++RRPRG++
Sbjct: 110 PYVLAKWRILNRLHDRNETLYYKVLMENIEEYAPIVYTPTVGLVCQKYSGLFRRPRGMYF 169
Query: 832 TIHDKGHVYDVLKNW 876
+ D+G + ++ NW
Sbjct: 170 SAEDRGEMMSMVYNW 184
>UniRef50_Q4QAQ6 Cluster: Malic enzyme, putative; n=20;
Trypanosomatidae|Rep: Malic enzyme, putative -
Leishmania major
Length = 573
Score = 80.6 bits (190), Expect = 5e-14
Identities = 38/125 (30%), Positives = 70/125 (56%)
Frame = +1
Query: 499 GLDHLKHPGLNKGMAFTIEERQLLGIHGLLPPRVKTQEEQVELCKLSIDRYENPLNKYIY 678
G+D+L++ NKG AFT ER + + GLLPP V+T ++QVE ++R+ P+N+Y
Sbjct: 19 GVDYLRNRFTNKGTAFTAAERSHMNVEGLLPPSVETLDDQVERYWDQLNRFNEPINRYQL 78
Query: 679 LMGLLDRNEHLFYRFVADXVADMMPLCTLRRLAWPXQKXXLVYRRPRGLFITIHDKGHVY 858
L + + N L+Y + + +P+ + Q+ +Y++ GL++ + KG V
Sbjct: 79 LRNVQNTNVTLYYAILTRYLKQTLPIVYTPTVGEACQRYGDLYQKDHGLYLDVASKGKVR 138
Query: 859 DVLKN 873
+++N
Sbjct: 139 RLIQN 143
>UniRef50_A2QY66 Cluster: Malic enzyme; n=2; cellular organisms|Rep:
Malic enzyme - Aspergillus niger
Length = 609
Score = 80.2 bits (189), Expect = 6e-14
Identities = 40/126 (31%), Positives = 66/126 (52%)
Frame = +1
Query: 499 GLDHLKHPGLNKGMAFTIEERQLLGIHGLLPPRVKTQEEQVELCKLSIDRYENPLNKYIY 678
G D L+ NKG AFT EER+ +HGLLPP ++T EEQV+ +N L K +
Sbjct: 57 GRDALQSCQFNKGSAFTEEERKTFKLHGLLPPNIQTLEEQVQRAYEQYSSRDNDLAKNTF 116
Query: 679 LMGLLDRNEHLFYRFVADXVADMMPLCTLRRLAWPXQKXXLVYRRPRGLFITIHDKGHVY 858
+ + +NE L+Y+ + + +M+ + Q ++R+P G F+ I D+ +
Sbjct: 117 MASMKAQNEVLYYKLIDTHLKEMLSIIYTPTEGDAIQNYSRLFRKPEGCFLNIRDQDRIE 176
Query: 859 DVLKNW 876
+ L N+
Sbjct: 177 ECLSNF 182
>UniRef50_Q9RYN4 Cluster: Malate oxidoreductase; n=6;
Deinococci|Rep: Malate oxidoreductase - Deinococcus
radiodurans
Length = 580
Score = 79.8 bits (188), Expect = 8e-14
Identities = 42/112 (37%), Positives = 62/112 (55%)
Frame = +1
Query: 499 GLDHLKHPGLNKGMAFTIEERQLLGIHGLLPPRVKTQEEQVELCKLSIDRYENPLNKYIY 678
G + + P LNKG AFT EER+ G+ GLL P+V + E +E + L K++Y
Sbjct: 37 GFNLTRIPLLNKGTAFTAEEREAHGLDGLLAPQVDSLEVLIERAYREFSKRGAALEKHVY 96
Query: 679 LMGLLDRNEHLFYRFVADXVADMMPLCTLRRLAWPXQKXXLVYRRPRGLFIT 834
L L DRNE LFY ++ V +M+P+ + +K +YR PRGL ++
Sbjct: 97 LRNLQDRNEVLFYALLSHHVEEMLPIVYTPTVGDAVKKFSQIYRYPRGLTLS 148
>UniRef50_A1SVL3 Cluster: Malic enzyme aka malate dehydrogenase
(Oxaloacetate-decarboxylating) (NADP(+)); n=4;
Gammaproteobacteria|Rep: Malic enzyme aka malate
dehydrogenase (Oxaloacetate-decarboxylating) (NADP(+)) -
Psychromonas ingrahamii (strain 37)
Length = 571
Score = 79.8 bits (188), Expect = 8e-14
Identities = 46/127 (36%), Positives = 70/127 (55%), Gaps = 3/127 (2%)
Frame = +1
Query: 478 QPTSGLSGLDHLKHPGLNKGMAFTIEERQLLGIHGLLPPRVKTQEEQVELCKLSIDRYEN 657
+P S L+G + L + LNK AFT +ER+ ++GLLPPRV+T E+Q++
Sbjct: 18 RPVS-LTGNELLNNRTLNKSTAFTYQEREDFDLNGLLPPRVQTFEDQLKRVYQGFSASST 76
Query: 658 PLNKYIYLMGLLDRNEHLFYRFVADXVADMMPLCTLRRLAWPXQKXXLVYRRPRGLFIT- 834
+ KY YL L DRNE LFY ++ + +M P+ + Q+ ++ RGL++T
Sbjct: 77 DIEKYQYLRALQDRNETLFYALISRNIEEMTPIIYTPTVGKACQEFSHRFQIARGLYLTT 136
Query: 835 --IHDKG 849
IHD G
Sbjct: 137 DNIHDVG 143
>UniRef50_A2EKE3 Cluster: Malic enzyme; n=14; Trichomonadidae|Rep:
Malic enzyme - Trichomonas vaginalis G3
Length = 567
Score = 77.8 bits (183), Expect = 3e-13
Identities = 43/128 (33%), Positives = 67/128 (52%), Gaps = 1/128 (0%)
Frame = +1
Query: 496 SGLDHLKHPGLNKGMAFTIEERQLLGIHGLLPPRVKTQEEQVELCKLSIDRYENPLNKYI 675
+G+ L+ LNKG AFT EER + GLLP +V T++EQ + + PL KYI
Sbjct: 23 TGMTLLQDGDLNKGTAFTKEERDRFNLRGLLPYKVFTKDEQAARIRRQFELMPTPLLKYI 82
Query: 676 YLMGLLDRNEHLFYRFV-ADXVADMMPLCTLRRLAWPXQKXXLVYRRPRGLFITIHDKGH 852
+L ++N F+RF+ + MP+ + QK + RG++IT D G
Sbjct: 83 FLANEREKNSQSFWRFLFTHPPEETMPILYTPTVGEACQKWATHRQSYRGIYITPEDSGK 142
Query: 853 VYDVLKNW 876
+ D+L+N+
Sbjct: 143 IKDILRNY 150
>UniRef50_Q4PC56 Cluster: Malic enzyme; n=1; Ustilago maydis|Rep:
Malic enzyme - Ustilago maydis (Smut fungus)
Length = 634
Score = 77.0 bits (181), Expect = 6e-13
Identities = 40/126 (31%), Positives = 63/126 (50%), Gaps = 2/126 (1%)
Frame = +1
Query: 505 DH--LKHPGLNKGMAFTIEERQLLGIHGLLPPRVKTQEEQVELCKLSIDRYENPLNKYIY 678
DH + P N+ F+ E+R LG+ GLLPP ++ QV + PL K++
Sbjct: 77 DHRIISDPFPNQDTGFSYEKRDQLGLRGLLPPAKQSLNTQVLRVLHQLRSKSTPLEKHVM 136
Query: 679 LMGLLDRNEHLFYRFVADXVADMMPLCTLRRLAWPXQKXXLVYRRPRGLFITIHDKGHVY 858
L L N L+Y + +++PL + QK +YRRP GL I++ DKG +
Sbjct: 137 LASLRQTNTRLYYATILANKEEILPLIYTPTVGEACQKFSHIYRRPEGLSISLEDKGKIA 196
Query: 859 DVLKNW 876
+++NW
Sbjct: 197 SIVENW 202
>UniRef50_Q4X1Z2 Cluster: NADP-dependent malic enzyme MaeA; n=11;
Pezizomycotina|Rep: NADP-dependent malic enzyme MaeA -
Aspergillus fumigatus (Sartorya fumigata)
Length = 661
Score = 75.4 bits (177), Expect = 2e-12
Identities = 34/106 (32%), Positives = 59/106 (55%)
Frame = +1
Query: 559 RQLLGIHGLLPPRVKTQEEQVELCKLSIDRYENPLNKYIYLMGLLDRNEHLFYRFVADXV 738
R+ L +GL PPR ++ E Q C + + ++K++YL L N HLFYR V D +
Sbjct: 102 RKYLRTYGLTPPRAESYEIQKTRCLAQLALKQTAIDKFLYLSTLRKNNVHLFYRLVTDHL 161
Query: 739 ADMMPLCTLRRLAWPXQKXXLVYRRPRGLFITIHDKGHVYDVLKNW 876
++ PL + QK +Y++P G++++ D+G++ V+ NW
Sbjct: 162 KELTPLIYTPVVGEACQKWSEIYQQPEGMYLSWEDRGNLAAVIANW 207
>UniRef50_Q9HE50 Cluster: Malic enzyme; n=6; Pezizomycotina|Rep:
Malic enzyme - Neurospora crassa
Length = 1023
Score = 74.5 bits (175), Expect = 3e-12
Identities = 37/115 (32%), Positives = 61/115 (53%)
Frame = +1
Query: 532 KGMAFTIEERQLLGIHGLLPPRVKTQEEQVELCKLSIDRYENPLNKYIYLMGLLDRNEHL 711
KG +FT EER + GL+P ++ E+QVE I + +++Y+YL + +N L
Sbjct: 483 KGTSFTPEERVAKNLTGLIPHVMEDSEKQVERALKMIRTRQTDIDRYLYLSTIKSQNVDL 542
Query: 712 FYRFVADXVADMMPLCTLRRLAWPXQKXXLVYRRPRGLFITIHDKGHVYDVLKNW 876
FYR + D +MMPL + + +Y RP L+I+I + + +L+NW
Sbjct: 543 FYRLLMDHAKEMMPLVYTPTIGDVCLQYSTLYTRPEALYISIKQRKSIRTILRNW 597
>UniRef50_A3QW96 Cluster: Malic enzyme; n=10; Tigriopus
californicus|Rep: Malic enzyme - Tigriopus californicus
(Marine copepod)
Length = 322
Score = 73.7 bits (173), Expect = 6e-12
Identities = 44/145 (30%), Positives = 69/145 (47%), Gaps = 19/145 (13%)
Frame = +1
Query: 499 GLDHLKHPGLNKGMAFTIEERQLLGIHGLLPPRVKTQEEQVELCKLSIDR------YENP 660
G + + P NKG+AF + ER L + GL+PPR+ + +EQ + R + P
Sbjct: 45 GRNLVSDPISNKGLAFPLSERDRLSVRGLVPPRILSIQEQERVIMDEYTRGWAARAEQEP 104
Query: 661 -------------LNKYIYLMGLLDRNEHLFYRFVADXVADMMPLCTLRRLAWPXQKXXL 801
+ K+ L + DRNE LFYR + D DM P+ + W
Sbjct: 105 EDEIIKSGVGPDNIRKWKVLQSVQDRNETLFYRILMDNFQDMAPIIYTPTVGWACSHFSQ 164
Query: 802 VYRRPRGLFITIHDKGHVYDVLKNW 876
+YRRPRG++ + D+G + ++ NW
Sbjct: 165 LYRRPRGMYFSHGDRGEMASMVYNW 189
>UniRef50_UPI0000D9F768 Cluster: PREDICTED: similar to Y48B6A.12,
partial; n=1; Macaca mulatta|Rep: PREDICTED: similar to
Y48B6A.12, partial - Macaca mulatta
Length = 456
Score = 73.3 bits (172), Expect = 7e-12
Identities = 35/98 (35%), Positives = 55/98 (56%)
Frame = +1
Query: 580 GLLPPRVKTQEEQVELCKLSIDRYENPLNKYIYLMGLLDRNEHLFYRFVADXVADMMPLC 759
GLLPP+V + Q C L + N + KYIYL L DRNE L+++ + D VA+MMP+
Sbjct: 34 GLLPPKVLDLDVQSRRCYLQFSQNSNDIEKYIYLESLHDRNETLYFKLLVDHVAEMMPIV 93
Query: 760 TLRRLAWPXQKXXLVYRRPRGLFITIHDKGHVYDVLKN 873
+ Q ++R RGL+ + +KG+ +++ N
Sbjct: 94 YTPVVGKACQLFGHIFRNARGLYFNLSEKGNFKEMVWN 131
>UniRef50_Q9S4T5 Cluster: NAD-malate oxidoreductase homolog; n=15;
Legionellales|Rep: NAD-malate oxidoreductase homolog -
Legionella pneumophila
Length = 117
Score = 73.3 bits (172), Expect = 7e-12
Identities = 37/90 (41%), Positives = 55/90 (61%)
Frame = +1
Query: 487 SGLSGLDHLKHPGLNKGMAFTIEERQLLGIHGLLPPRVKTQEEQVELCKLSIDRYENPLN 666
+ L G L P LNKG AFT EER+ G+ G LP RV+T +EQV+ L Y L
Sbjct: 19 TSLCGKPLLTTPQLNKGTAFTQEERKDFGLLGKLPHRVETLDEQVKRAYLQYSSYTTRLQ 78
Query: 667 KYIYLMGLLDRNEHLFYRFVADXVADMMPL 756
++IYL L D+N+ +FY+ ++ + +M+P+
Sbjct: 79 QHIYLNNLHDKNQIVFYKLLSRHLGEMLPI 108
>UniRef50_Q8Y5Y8 Cluster: Lmo1915 protein; n=15; Firmicutes|Rep:
Lmo1915 protein - Listeria monocytogenes
Length = 547
Score = 72.1 bits (169), Expect = 2e-11
Identities = 35/87 (40%), Positives = 51/87 (58%)
Frame = +1
Query: 496 SGLDHLKHPGLNKGMAFTIEERQLLGIHGLLPPRVKTQEEQVELCKLSIDRYENPLNKYI 675
SG D++ +P LNKG AF+ EER + GLLPP ++T E+Q + I+ E PL+K+
Sbjct: 5 SGFDYMNNPLLNKGTAFSKEERASYQLDGLLPPIIETIEQQAVRIETQIENLETPLHKHR 64
Query: 676 YLMGLLDRNEHLFYRFVADXVADMMPL 756
L L + N L+Y V V D +P+
Sbjct: 65 LLTNLYNENRTLYYYVVTKNVTDYLPI 91
>UniRef50_Q48796 Cluster: Malolactic enzyme; n=49; Bacteria|Rep:
Malolactic enzyme - Oenococcus oeni (Leuconostoc oenos)
Length = 541
Score = 71.3 bits (167), Expect = 3e-11
Identities = 39/122 (31%), Positives = 65/122 (53%), Gaps = 1/122 (0%)
Frame = +1
Query: 511 LKHPGLNKGMAFTIEERQLLGIHGLLPPRVKTQEEQVELCKLSIDRYENPLNKYIYLMGL 690
L P +NKG AFT ER+ LG++GLLP +V+ +EQV+ + L K ++LM +
Sbjct: 8 LNDPFINKGTAFTEAEREELGLNGLLPAKVQALQEQVDQTYAQFQSKVSNLEKRLFLMEI 67
Query: 691 LDRNEHLFYRFVADXVADMMPLCTLRRLAWPXQKXXLVYRRPRG-LFITIHDKGHVYDVL 867
+ N LFY+ + V + MP+ +A + ++ P+G F+ I+ ++ L
Sbjct: 68 FNTNHVLFYKLFSQHVVEFMPIVYDPTIADTIENYSELFVEPQGAAFLDINHPENIQSTL 127
Query: 868 KN 873
KN
Sbjct: 128 KN 129
>UniRef50_Q5CS07 Cluster: Malic enzyme; n=2; Cryptosporidium|Rep:
Malic enzyme - Cryptosporidium parvum Iowa II
Length = 614
Score = 69.7 bits (163), Expect = 9e-11
Identities = 40/142 (28%), Positives = 75/142 (52%), Gaps = 4/142 (2%)
Frame = +1
Query: 463 APGXGQPTSGLSGLDHLKHPGLNKGMAFTIEERQLLGIHGLLPPRVKTQEEQVELCKLSI 642
AP + L G++ L++P NKG++FT+EER+ G+ GLLP + +T +EQV +I
Sbjct: 54 APSLRKKPIELKGIELLRNPFYNKGLSFTMEERKEYGLEGLLPAKYETIDEQVSRLWTAI 113
Query: 643 DRYENPLNKYIYLMGLLDRNEHLFYRFVADXVADMMPLC---TLRRLAWPXQKXXLVYR- 810
++ ++ + KY +L + + LF+ + D+ PL T+ + +
Sbjct: 114 NKIDSNIGKYTFLENIRSSSFILFHSLLDKYFKDLTPLVYTPTVGEGCIEFSRNPTIRNW 173
Query: 811 RPRGLFITIHDKGHVYDVLKNW 876
GL++ KG +Y++LK++
Sbjct: 174 LGSGLYLNKSHKGRIYEILKDF 195
>UniRef50_P40375 Cluster: NAD-dependent malic enzyme; n=3;
Schizosaccharomyces pombe|Rep: NAD-dependent malic
enzyme - Schizosaccharomyces pombe (Fission yeast)
Length = 565
Score = 67.3 bits (157), Expect = 5e-10
Identities = 41/119 (34%), Positives = 61/119 (51%), Gaps = 4/119 (3%)
Frame = +1
Query: 493 LSGLDHLKHPGLNKGMAFTIEERQLLGIHGLLPPRVKTQEEQVELCKLSIDRY----ENP 660
L G+ L P NK AFT EERQ I LPP V+T ++QV+ C D+Y + P
Sbjct: 13 LKGVTLLNSPRYNKDTAFTPEERQKFEISSRLPPIVETLQQQVDRC---YDQYKAIGDEP 69
Query: 661 LNKYIYLMGLLDRNEHLFYRFVADXVADMMPLCTLRRLAWPXQKXXLVYRRPRGLFITI 837
L K +YL L N+ LFY ++ + +M+P+ ++ +YR P G ++ I
Sbjct: 70 LQKNLYLSQLSVTNQTLFYALISQHLIEMIPIIYTPTEGDAIKQFSDIYRYPEGCYLDI 128
>UniRef50_Q5KEY3 Cluster: Malic enzyme; n=1; Filobasidiella
neoformans|Rep: Malic enzyme - Cryptococcus neoformans
(Filobasidiella neoformans)
Length = 629
Score = 64.9 bits (151), Expect = 3e-09
Identities = 37/116 (31%), Positives = 60/116 (51%)
Frame = +1
Query: 487 SGLSGLDHLKHPGLNKGMAFTIEERQLLGIHGLLPPRVKTQEEQVELCKLSIDRYENPLN 666
+ L G L P LNKG FT EERQ+ G+ G LP V + E+Q + + + +
Sbjct: 48 TNLRGSALLNTPRLNKGAGFTREERQIFGLEGFLPYDVHSLEKQCLRAYNQLCKQPSVIL 107
Query: 667 KYIYLMGLLDRNEHLFYRFVADXVADMMPLCTLRRLAWPXQKXXLVYRRPRGLFIT 834
K+ +L L D+N+ LFYR + D + +++ + A ++RRP G +I+
Sbjct: 108 KHAFLASLRDQNQVLFYRLMQDRLKELLGVLYTPGAAEAVAGYSSLFRRPVGCYIS 163
>UniRef50_Q95061 Cluster: Malic enzyme; n=2; Giardia
intestinalis|Rep: Malic enzyme - Giardia lamblia
(Giardia intestinalis)
Length = 557
Score = 64.5 bits (150), Expect = 3e-09
Identities = 36/123 (29%), Positives = 58/123 (47%), Gaps = 1/123 (0%)
Frame = +1
Query: 511 LKHPGLNKGMAFTIEERQLLGIHGLLPPRVKTQEEQVELCKLSIDRYENPLNKYIYLMGL 690
L++ NK AFT ER+ I LP RV+T E+Q+ C+ D P K++YL L
Sbjct: 9 LRNKDCNKDTAFTAAEREAHHIVARLPARVETIEQQISRCRAQFDVLTTPTEKWLYLTRL 68
Query: 691 LDRNEHLFYRFVADXVADMMPLCTLRRLAWPXQKXXLVYR-RPRGLFITIHDKGHVYDVL 867
+ NE LF F + +++P+ + L+++ PRG ++ G V +
Sbjct: 69 QEVNETLFSGFCLKYLKEVLPIVYTPTVGTACSNYSLLWQGYPRGFYLNRTHLGKVKQIF 128
Query: 868 KNW 876
W
Sbjct: 129 DQW 131
>UniRef50_Q6AL43 Cluster: Related to NAD-dependent malic enzyme;
n=1; Desulfotalea psychrophila|Rep: Related to
NAD-dependent malic enzyme - Desulfotalea psychrophila
Length = 578
Score = 62.1 bits (144), Expect = 2e-08
Identities = 33/116 (28%), Positives = 54/116 (46%)
Frame = +1
Query: 529 NKGMAFTIEERQLLGIHGLLPPRVKTQEEQVELCKLSIDRYENPLNKYIYLMGLLDRNEH 708
NK AF+ +ER G+ G LPP + E QVE C + + E+ KYI++ L DRN
Sbjct: 35 NKSTAFSSKERDDFGLQGSLPPGFRDLEAQVENCHIKLGEKESEEEKYIFIRSLFDRNVT 94
Query: 709 LFYRFVADXVADMMPLCTLRRLAWPXQKXXLVYRRPRGLFITIHDKGHVYDVLKNW 876
L + + + M + + QK ++R+ GL + D+L+ +
Sbjct: 95 LAHALIQSDLEKFMGIIYTPTVGLAVQKYSAMFRQANGLHFSPDTIDQAEDILRRF 150
>UniRef50_P36013 Cluster: NAD-dependent malic enzyme, mitochondrial
precursor; n=15; Saccharomycetales|Rep: NAD-dependent
malic enzyme, mitochondrial precursor - Saccharomyces
cerevisiae (Baker's yeast)
Length = 669
Score = 60.9 bits (141), Expect = 4e-08
Identities = 33/115 (28%), Positives = 56/115 (48%)
Frame = +1
Query: 493 LSGLDHLKHPGLNKGMAFTIEERQLLGIHGLLPPRVKTQEEQVELCKLSIDRYENPLNKY 672
L L P NKG AFT EER+ + LLPP+V T +EQ+E + + PL K
Sbjct: 98 LESFQLLNSPLFNKGSAFTQEEREAFNLEALLPPQVNTLDEQLERSYKQLCYLKTPLAKN 157
Query: 673 IYLMGLLDRNEHLFYRFVADXVADMMPLCTLRRLAWPXQKXXLVYRRPRGLFITI 837
++ L +N+ L++ + + +++P+ +R+P G+F+ I
Sbjct: 158 DFMTSLRVQNKVLYFALIRRHIKELVPIIYTPTEGDAIAAYSHRFRKPEGVFLDI 212
>UniRef50_Q2HCG7 Cluster: Malic enzyme; n=1; Chaetomium
globosum|Rep: Malic enzyme - Chaetomium globosum (Soil
fungus)
Length = 586
Score = 59.7 bits (138), Expect = 1e-07
Identities = 37/128 (28%), Positives = 61/128 (47%)
Frame = +1
Query: 493 LSGLDHLKHPGLNKGMAFTIEERQLLGIHGLLPPRVKTQEEQVELCKLSIDRYENPLNKY 672
L G L H NKG AFT EER+ + GLLP ++T ++QV+ + L K
Sbjct: 31 LKGTVLLNHSYFNKGSAFTKEERRDFELSGLLPQSIQTLDQQVQRAYEQYSARPDDLAKN 90
Query: 673 IYLMGLLDRNEHLFYRFVADXVADMMPLCTLRRLAWPXQKXXLVYRRPRGLFITIHDKGH 852
+L + ++NE L+++ M + + ++RRP+G+F+ +HD
Sbjct: 91 TFLTSMKEQNEVLYFK--------MFSVVYTPTEGDAIENFSRLFRRPQGVFLNVHDCDR 142
Query: 853 VYDVLKNW 876
V+ L W
Sbjct: 143 VHHDLSLW 150
>UniRef50_Q01AM5 Cluster: NADP+-dependent malic enzyme; n=2;
Ostreococcus|Rep: NADP+-dependent malic enzyme -
Ostreococcus tauri
Length = 580
Score = 58.4 bits (135), Expect = 2e-07
Identities = 31/126 (24%), Positives = 61/126 (48%)
Frame = +1
Query: 499 GLDHLKHPGLNKGMAFTIEERQLLGIHGLLPPRVKTQEEQVELCKLSIDRYENPLNKYIY 678
G L+ +G+A +R+ G+ GL+P +E ++ ++ + E P KY
Sbjct: 48 GYASLRDASAYRGLA--TNDRRGKGVDGLIPAGEVGEEVEIARANAALAQCETPFEKYKQ 105
Query: 679 LMGLLDRNEHLFYRFVADXVADMMPLCTLRRLAWPXQKXXLVYRRPRGLFITIHDKGHVY 858
L+ L +E FYR + ++P+ + K + +RP GL+++ +D G+V
Sbjct: 106 LVALQMTDESTFYRMLRSQTETLLPILYTPTVGEACVKFGTLVQRPMGLWVSSNDAGNVK 165
Query: 859 DVLKNW 876
+++NW
Sbjct: 166 QLIRNW 171
>UniRef50_A6XP71 Cluster: Malic enzyme protein 2; n=2;
Mucoromycotina|Rep: Malic enzyme protein 2 - Mortierella
alpina (Mortierella renispora)
Length = 669
Score = 54.0 bits (124), Expect = 5e-06
Identities = 36/134 (26%), Positives = 63/134 (47%), Gaps = 10/134 (7%)
Frame = +1
Query: 505 DHL----KHPGLNKGMAFTIEERQLLGIHGLLPPRVKTQEEQVELCKLSIDRYENPLNKY 672
DHL +H G A E R L + GL P +V++ E Q + + + + KY
Sbjct: 95 DHLSNTHQHTDNMTGTATPTELRSALHLQGLTPAKVESFELQKKRALAQLRSKSSDIEKY 154
Query: 673 IYLMGLLDRNEHLFYRFVADXVADMMPLCTLRRLAWPXQKXXLVY------RRPRGLFIT 834
++L L + N LFY V D + + +PL + Q +Y +P GLF++
Sbjct: 155 VFLAWLRNTNVRLFYGLVGDQLEETLPLIYTPTVGTACQNYSSIYPFLAPPGQPDGLFLS 214
Query: 835 IHDKGHVYDVLKNW 876
I+D ++ +++N+
Sbjct: 215 INDLPNLTQIIQNY 228
>UniRef50_Q5KBK5 Cluster: Nad-dependent malic enzyme, putative; n=2;
Filobasidiella neoformans|Rep: Nad-dependent malic
enzyme, putative - Cryptococcus neoformans
(Filobasidiella neoformans)
Length = 584
Score = 50.8 bits (116), Expect = 4e-05
Identities = 32/108 (29%), Positives = 49/108 (45%)
Frame = +1
Query: 511 LKHPGLNKGMAFTIEERQLLGIHGLLPPRVKTQEEQVELCKLSIDRYENPLNKYIYLMGL 690
L +P NKG AFT +ER + G LP V + E QV+ E + K +L +
Sbjct: 32 LNNPRFNKGSAFTHQERSEFALRGRLPYAVDSLEIQVKRAYEQYKSRETNILKNSFLQSM 91
Query: 691 LDRNEHLFYRFVADXVADMMPLCTLRRLAWPXQKXXLVYRRPRGLFIT 834
+N LFY + + +M P+ A ++RR GL++T
Sbjct: 92 KAQNWTLFYALLQAHLVEMFPIVYTPTEADAIADYSHLFRRSEGLYLT 139
>UniRef50_A3BK03 Cluster: Malic enzyme; n=2; Oryza sativa|Rep: Malic
enzyme - Oryza sativa subsp. japonica (Rice)
Length = 635
Score = 46.0 bits (104), Expect = 0.001
Identities = 22/75 (29%), Positives = 40/75 (53%), Gaps = 2/75 (2%)
Frame = +1
Query: 658 PLNKYIYLMGLLDRNEHLFYR--FVADXVADMMPLCTLRRLAWPXQKXXLVYRRPRGLFI 831
PL K+ L L DRNE ++Y+ + D + + P+ + Q ++RRPRG++
Sbjct: 144 PLAKWRILNRLHDRNETMYYKAEVLIDNIEEHAPIVYTPTVGLVCQNYSGLFRRPRGMYF 203
Query: 832 TIHDKGHVYDVLKNW 876
+ D+G + ++ NW
Sbjct: 204 SAEDRGEMMSMVYNW 218
Score = 44.0 bits (99), Expect = 0.005
Identities = 18/42 (42%), Positives = 27/42 (64%)
Frame = +1
Query: 499 GLDHLKHPGLNKGMAFTIEERQLLGIHGLLPPRVKTQEEQVE 624
G D L P N+G F++ ER LG+ GLLPP V + ++Q++
Sbjct: 45 GSDILHDPWFNRGTGFSMTERDRLGLRGLLPPNVVSSQQQID 86
>UniRef50_A4SKB8 Cluster: NAD-dependent malic enzyme; n=2;
Aeromonas|Rep: NAD-dependent malic enzyme - Aeromonas
salmonicida (strain A449)
Length = 516
Score = 44.4 bits (100), Expect = 0.004
Identities = 23/104 (22%), Positives = 51/104 (49%)
Frame = +1
Query: 535 GMAFTIEERQLLGIHGLLPPRVKTQEEQVELCKLSIDRYENPLNKYIYLMGLLDRNEHLF 714
G + ER+ G+ G +P + ++ +Q + ++P ++++ L L + N LF
Sbjct: 7 GTSLPYAERKRQGLMGRMPHKEESLAQQRRRIYRLVSAMQSPFDQHLLLRQLQEDNPVLF 66
Query: 715 YRFVADXVADMMPLCTLRRLAWPXQKXXLVYRRPRGLFITIHDK 846
Y V + +++P+ + Q+ +Y R GL+++ HD+
Sbjct: 67 YDLVRHHLPELLPIIYTPVVGEACQRHSDLYLRSHGLYLSWHDR 110
>UniRef50_Q5K758 Cluster: Malic enzyme; n=1; Filobasidiella
neoformans|Rep: Malic enzyme - Cryptococcus neoformans
(Filobasidiella neoformans)
Length = 600
Score = 44.4 bits (100), Expect = 0.004
Identities = 19/82 (23%), Positives = 40/82 (48%)
Frame = +1
Query: 631 KLSIDRYENPLNKYIYLMGLLDRNEHLFYRFVADXVADMMPLCTLRRLAWPXQKXXLVYR 810
K + PL K+++L + + +LF+ + D + ++ P+ + QK +Y
Sbjct: 95 KAHLQNLPTPLLKHVHLSKIRREDPNLFFSVMRDELTELAPIVYTPTVGEACQKYSQIYS 154
Query: 811 RPRGLFITIHDKGHVYDVLKNW 876
P GL++ I DK + ++L +
Sbjct: 155 GPEGLYLNIEDKDRIPEILHQY 176
>UniRef50_A3YYQ0 Cluster: Malate oxidoreductase; n=1; Synechococcus
sp. WH 5701|Rep: Malate oxidoreductase - Synechococcus
sp. WH 5701
Length = 517
Score = 41.1 bits (92), Expect = 0.036
Identities = 26/91 (28%), Positives = 44/91 (48%), Gaps = 1/91 (1%)
Frame = +1
Query: 598 VKTQEEQVELCKLSIDRYENPLNKYIYLMGLLDRNEHLFYRFVADXVADMMPLCTLRRLA 777
+++ E QVE + N L ++ + + L N LF+RF+AD + +MP+ +
Sbjct: 1 MESLETQVERHWQAFLSLRNDLERFRFAVALRQANLTLFHRFLADHIEAVMPIVYTPTVG 60
Query: 778 WPXQKXXLVYRRPR-GLFITIHDKGHVYDVL 867
Q+ L YR P G+F+ D + VL
Sbjct: 61 AAIQRFSLDYRTPSGGVFLAAPDLERIESVL 91
>UniRef50_Q97XF3 Cluster: Putative uncharacterized protein; n=1;
Sulfolobus solfataricus|Rep: Putative uncharacterized
protein - Sulfolobus solfataricus
Length = 241
Score = 35.5 bits (78), Expect = 1.8
Identities = 17/49 (34%), Positives = 30/49 (61%), Gaps = 1/49 (2%)
Frame = -2
Query: 227 NFTKELLLEISEIRYIDTFVHKSFTYYNLFK-EKRKDSRELLQVFIATS 84
N T L L+ I Y+ T ++K +TY +FK E++K++ +L Q+ + S
Sbjct: 176 NLTSLLDLKFKVINYVPTNLYKEYTYMEIFKREEKKNTFDLTQINVGLS 224
>UniRef50_Q3IFJ8 Cluster: Putative D-cysteine desulfhydrase,
PLP-dependent enzyme; n=2; Alteromonadales|Rep: Putative
D-cysteine desulfhydrase, PLP-dependent enzyme -
Pseudoalteromonas haloplanktis (strain TAC 125)
Length = 302
Score = 34.7 bits (76), Expect = 3.1
Identities = 19/41 (46%), Positives = 22/41 (53%), Gaps = 3/41 (7%)
Frame = +1
Query: 415 GSVRIAKWNVIVSDYGAPG---XGQPTSGLSGLDHLKHPGL 528
G + A W +I DY APG T GL GLD LK+ GL
Sbjct: 261 GKMMHALWQLIAQDYFAPGSKIIAVHTGGLQGLDGLKYRGL 301
>UniRef50_Q08PM3 Cluster: Hemin ABC transporter, periplasmic
hemin-binding protein; n=1; Stigmatella aurantiaca
DW4/3-1|Rep: Hemin ABC transporter, periplasmic
hemin-binding protein - Stigmatella aurantiaca DW4/3-1
Length = 332
Score = 34.3 bits (75), Expect = 4.1
Identities = 27/85 (31%), Positives = 38/85 (44%)
Frame = +1
Query: 604 TQEEQVELCKLSIDRYENPLNKYIYLMGLLDRNEHLFYRFVADXVADMMPLCTLRRLAWP 783
T EQ+ KL + EN + I GLL R E L F A+ M R++A
Sbjct: 143 TSAEQLRGAKLPVLILENSSKEGI--SGLLRRIEVLARVFNAEEAGQRMKQDITRQVAEL 200
Query: 784 XQKXXLVYRRPRGLFITIHDKGHVY 858
+K L ++PR LF+ H G +
Sbjct: 201 EKKIALAKKKPRVLFLYAHSPGEAF 225
>UniRef50_A4RZU1 Cluster: Malic enzyme; n=2; Ostreococcus|Rep: Malic
enzyme - Ostreococcus lucimarinus CCE9901
Length = 539
Score = 34.3 bits (75), Expect = 4.1
Identities = 18/67 (26%), Positives = 30/67 (44%)
Frame = +1
Query: 655 NPLNKYIYLMGLLDRNEHLFYRFVADXVADMMPLCTLRRLAWPXQKXXLVYRRPRGLFIT 834
+PL +Y+YL L + FYR + ++MP + +K + G++IT
Sbjct: 16 DPLERYVYLRELQRASAETFYRALVREPLELMPFVYTPTVGEACEKYHRLGIETNGVYIT 75
Query: 835 IHDKGHV 855
D G V
Sbjct: 76 ADDAGRV 82
>UniRef50_Q2H899 Cluster: Putative uncharacterized protein; n=1;
Chaetomium globosum|Rep: Putative uncharacterized
protein - Chaetomium globosum (Soil fungus)
Length = 667
Score = 34.3 bits (75), Expect = 4.1
Identities = 12/32 (37%), Positives = 18/32 (56%)
Frame = -1
Query: 843 IVDRDEEAPWSAVHKPXLLXRPGQPSECTQWH 748
+ E AP++A P +PGQP+ C +WH
Sbjct: 203 VTSYSESAPYTATAFPPQHTQPGQPANCNRWH 234
>UniRef50_Q4SHK3 Cluster: Chromosome 5 SCAF14581, whole genome
shotgun sequence; n=1; Tetraodon nigroviridis|Rep:
Chromosome 5 SCAF14581, whole genome shotgun sequence -
Tetraodon nigroviridis (Green puffer)
Length = 72
Score = 33.9 bits (74), Expect = 5.5
Identities = 19/50 (38%), Positives = 24/50 (48%)
Frame = -2
Query: 632 LHSSTCSSCVLTRGGNNPCMPKS*RSSMVKAMPLLRPGCLRWSRPERPLV 483
L S SS +RG P P SS ++ R G RWSRP RP++
Sbjct: 22 LKGSAASSAAASRGQKTPASPTVPGSSQLQT----RSGQARWSRPRRPML 67
>UniRef50_Q116W6 Cluster: Putative uncharacterized protein; n=1;
Trichodesmium erythraeum IMS101|Rep: Putative
uncharacterized protein - Trichodesmium erythraeum
(strain IMS101)
Length = 1107
Score = 33.9 bits (74), Expect = 5.5
Identities = 19/56 (33%), Positives = 30/56 (53%), Gaps = 1/56 (1%)
Frame = +1
Query: 556 ERQLLGIHGL-LPPRVKTQEEQVELCKLSIDRYENPLNKYIYLMGLLDRNEHLFYR 720
E LLGI + LP ++K E + + +L+I NP+ I + G L N ++F R
Sbjct: 641 EINLLGIATMMLPTKLKDNYEPIAMAELAIAGRFNPMEGVILIQGQLTENSYIFSR 696
>UniRef50_Q4RNM6 Cluster: Chromosome 21 SCAF15012, whole genome
shotgun sequence; n=1; Tetraodon nigroviridis|Rep:
Chromosome 21 SCAF15012, whole genome shotgun sequence -
Tetraodon nigroviridis (Green puffer)
Length = 1187
Score = 33.5 bits (73), Expect = 7.2
Identities = 20/51 (39%), Positives = 26/51 (50%)
Frame = -2
Query: 650 YLSIESLHSSTCSSCVLTRGGNNPCMPKS*RSSMVKAMPLLRPGCLRWSRP 498
Y S+ES + T SC L G+ +P+S RSS L RP +WS P
Sbjct: 255 YNSLESSYQRTLQSC-LKSSGSVASLPQSDRSSSSSQESLNRPLTSKWSAP 304
>UniRef50_A4XFU6 Cluster: Binding-protein-dependent transport
systems inner membrane component precursor; n=1;
Caldicellulosiruptor saccharolyticus DSM 8903|Rep:
Binding-protein-dependent transport systems inner
membrane component precursor - Caldicellulosiruptor
saccharolyticus (strain ATCC 43494 / DSM 8903)
Length = 279
Score = 33.5 bits (73), Expect = 7.2
Identities = 18/50 (36%), Positives = 24/50 (48%)
Frame = -2
Query: 326 FAPFHFPNVADRAINLTFAAVAIHSARQIFHFQNFTKELLLEISEIRYID 177
F F + DR I L F V + IF +NF +++ EI E YID
Sbjct: 129 FVQFKVFGLLDRRITLIFPYVGLGLPMAIFLMENFIRDIPHEIEEAAYID 178
>UniRef50_A6LMP2 Cluster: Diguanylate cyclase; n=1; Thermosipho
melanesiensis BI429|Rep: Diguanylate cyclase -
Thermosipho melanesiensis BI429
Length = 465
Score = 33.1 bits (72), Expect = 9.5
Identities = 26/84 (30%), Positives = 48/84 (57%), Gaps = 10/84 (11%)
Frame = -2
Query: 248 RQIFHFQNFTKE---LLLEISEIRYI-DTFVHKS-----FTYYNLFKEKRKDSRELLQVF 96
R IF F+NF+ E + ++I++++ I DTF HK+ + K+ + + L+++
Sbjct: 339 RNIFEFENFSSEDVFIYIDINKLKEINDTFGHKTGDKILVKFSQTVKQFIRKNDLLIRLG 398
Query: 95 IATSLVILSN-SRRRLKKILRNSL 27
L++L N S+R+ KKI+ N L
Sbjct: 399 GDEFLLVLKNCSKRKGKKIINNIL 422
>UniRef50_Q4P7L2 Cluster: Putative uncharacterized protein; n=1;
Ustilago maydis|Rep: Putative uncharacterized protein -
Ustilago maydis (Smut fungus)
Length = 1444
Score = 33.1 bits (72), Expect = 9.5
Identities = 15/37 (40%), Positives = 18/37 (48%)
Frame = +3
Query: 333 MSPAPPAHCNKTGVPFSAVKQSQATSGGKCTYSEMER 443
M P PP+ VP SA SQA G+CT + R
Sbjct: 713 MLPTPPSFAPSPAVPVSAAPDSQALGTGQCTIANPSR 749
Database: uniref50
Posted date: Oct 5, 2007 11:19 AM
Number of letters in database: 575,637,011
Number of sequences in database: 1,657,284
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 848,750,615
Number of Sequences: 1657284
Number of extensions: 17076109
Number of successful extensions: 44913
Number of sequences better than 10.0: 68
Number of HSP's better than 10.0 without gapping: 42975
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 44859
length of database: 575,637,011
effective HSP length: 100
effective length of database: 409,908,611
effective search space used: 78292544701
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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