Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= MFBP08_F_P06
(885 letters)
Database: uniref50
1,657,284 sequences; 575,637,011 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
UniRef50_Q9VK80 Cluster: CG17024-PA; n=1; Drosophila melanogaste... 149 1e-34
UniRef50_UPI0000F33553 Cluster: phosphoribosylaminoimidazole car... 137 3e-31
UniRef50_P22234 Cluster: Multifunctional protein ADE2 [Includes:... 134 2e-30
UniRef50_A5UWC5 Cluster: Phosphoribosylaminoimidazolesuccinocarb... 97 4e-19
UniRef50_Q6NRP1 Cluster: LOC431975 protein; n=2; Xenopus|Rep: LO... 91 3e-17
UniRef50_Q5FIU8 Cluster: Phosphoribosylaminoimidazole-succinocar... 77 8e-13
UniRef50_Q4J8G0 Cluster: Phosphoribosylaminoimidazole-succinocar... 75 2e-12
UniRef50_Q49WJ0 Cluster: Phosphoribosylaminoimidazole-succinocar... 71 5e-11
UniRef50_Q7M9X5 Cluster: Phosphoribosylaminoimidazole-succinocar... 68 4e-10
UniRef50_Q7V5X1 Cluster: Phosphoribosylaminoimidazole-succinocar... 67 6e-10
UniRef50_Q87Y59 Cluster: Phosphoribosylaminoimidazole-succinocar... 66 1e-09
UniRef50_Q58987 Cluster: Phosphoribosylaminoimidazole-succinocar... 66 1e-09
UniRef50_Q8TIS9 Cluster: Phosphoribosylaminoimidazole-succinocar... 66 1e-09
UniRef50_Q8G5A9 Cluster: Phosphoribosylaminoimidazole-succinocar... 64 3e-09
UniRef50_P12046 Cluster: Phosphoribosylaminoimidazole-succinocar... 63 8e-09
UniRef50_P0A7E0 Cluster: Phosphoribosylaminoimidazole-succinocar... 62 1e-08
UniRef50_Q8ES99 Cluster: Phosphoribosylaminoimidazole-succinocar... 62 1e-08
UniRef50_O57978 Cluster: Phosphoribosylaminoimidazole-succinocar... 62 2e-08
UniRef50_Q92AN6 Cluster: Phosphoribosylaminoimidazole-succinocar... 61 3e-08
UniRef50_Q466M0 Cluster: Phosphoribosylaminoimidazole carboxylas... 60 6e-08
UniRef50_Q8TX83 Cluster: Phosphoribosylaminoimidazole-succinocar... 60 6e-08
UniRef50_Q8ZCD2 Cluster: Phosphoribosylaminoimidazole-succinocar... 59 1e-07
UniRef50_Q9X0X0 Cluster: Phosphoribosylaminoimidazole-succinocar... 58 4e-07
UniRef50_UPI00015BB105 Cluster: phosphoribosylaminoimidazole-suc... 57 5e-07
UniRef50_A4M8A0 Cluster: Phosphoribosylaminoimidazole-succinocar... 56 2e-06
UniRef50_Q98NM8 Cluster: Phosphoribosylaminoimidazole-succinocar... 56 2e-06
UniRef50_Q3YRB0 Cluster: SAICAR synthetase; n=2; Anaplasmataceae... 54 4e-06
UniRef50_Q6LZT3 Cluster: Phosphoribosylaminoimidazole-succinocar... 53 1e-05
UniRef50_Q9RXT0 Cluster: Phosphoribosylaminoimidazole-succinocar... 52 1e-05
UniRef50_A3H6Y2 Cluster: Phosphoribosylaminoimidazole-succinocar... 51 3e-05
UniRef50_Q8ZZK5 Cluster: Phosphoribosylaminoimidazole-succinocar... 51 3e-05
UniRef50_Q648Z8 Cluster: Phosphoribosylaminoimidazolesuccinocarb... 50 1e-04
UniRef50_Q88U22 Cluster: Phosphoribosylaminoimidazole-succinocar... 46 0.001
UniRef50_Q5JD27 Cluster: Phosphoribosylaminoimidazolesuccinocarb... 44 0.004
UniRef50_Q03Y92 Cluster: Phosphoribosylaminoimidazolesuccinocarb... 44 0.007
UniRef50_A6QAA3 Cluster: Phosphoribosylaminoimidazole-succinocar... 41 0.036
UniRef50_P38025 Cluster: Phosphoribosylaminoimidazole-succinocar... 41 0.036
UniRef50_P73471 Cluster: Phosphoribosylaminoimidazole-succinocar... 41 0.048
UniRef50_Q3ET89 Cluster: Phosphoribosylamidoimidazole-succinocar... 40 0.11
UniRef50_Q5IWX2 Cluster: Plastid phosphoribosylaminoimidazole-su... 38 0.26
UniRef50_A1G3E0 Cluster: SAICAR synthetase; n=1; Salinispora are... 36 1.8
UniRef50_Q4UML8 Cluster: Phosphoribosylaminoimidazole-succinocar... 36 1.8
UniRef50_A7DSW8 Cluster: Phosphoribosylaminoimidazolesuccinocarb... 34 4.2
UniRef50_Q8QTC7 Cluster: WSSV346; n=2; Shrimp white spot syndrom... 33 7.3
UniRef50_A4SAQ9 Cluster: Phosphoribosylaminoimidazole-succinocar... 33 7.3
>UniRef50_Q9VK80 Cluster: CG17024-PA; n=1; Drosophila
melanogaster|Rep: CG17024-PA - Drosophila melanogaster
(Fruit fly)
Length = 395
Score = 149 bits (360), Expect = 1e-34
Identities = 67/117 (57%), Positives = 86/117 (73%)
Frame = +1
Query: 169 VGQYXXXXXXXXXXXXQVFDVPDQPGYCLLLNKDRITAGDGVKAHDLEGKAAISNQTNAK 348
+G Y +V+D+PD PG CLLL+KDRITA DG+ AH+L+GKAAISN TN
Sbjct: 6 IGGYQLGKILIEGKTKKVYDLPDHPGLCLLLSKDRITAFDGLMAHELQGKAAISNTTNGL 65
Query: 349 VFEILKSAGIKTAFVKIASETAFLSKKCEMIPIEWVTRRLATGSFLKRNPGVPEGFR 519
VF +L AGI+TA+V + AF+++KC+M+ IEWVTRRLATGSF+K NP VPEG+R
Sbjct: 66 VFRLLNEAGIRTAYVDQCGDNAFIARKCQMVHIEWVTRRLATGSFIKLNPEVPEGYR 122
Score = 83.4 bits (197), Expect = 7e-15
Identities = 33/56 (58%), Positives = 45/56 (80%)
Frame = +2
Query: 521 FTPPKQETFFKDDANHDPQWSEEQIISAKFNYNGLLIGRDEVDYMRKATILIFEIL 688
F PPKQET FKDD++HDP W +EQI+S+ F NGL+IG DEV MR+ ++++FE+L
Sbjct: 123 FAPPKQETCFKDDSSHDPLWCDEQILSSNFECNGLIIGADEVQIMRRTSLVVFEVL 178
Score = 73.3 bits (172), Expect = 7e-12
Identities = 27/45 (60%), Positives = 37/45 (82%)
Frame = +3
Query: 690 EKAWALRDCALIDMKIXFGVDTEGXIVLXDVIDSDSWRLWPXXDK 824
E+AW ++CAL+DMK+ FGVD +G I+L D+IDSD+WR+WP DK
Sbjct: 179 ERAWKTKNCALVDMKVEFGVDEDGNILLADIIDSDTWRIWPAGDK 223
>UniRef50_UPI0000F33553 Cluster: phosphoribosylaminoimidazole
carboxylase, phosphoribosylaminoimidazole
succinocarboxamide synthetase; n=2; Coelomata|Rep:
phosphoribosylaminoimidazole carboxylase,
phosphoribosylaminoimidazole succinocarboxamide
synthetase - Bos Taurus
Length = 402
Score = 137 bits (332), Expect = 3e-31
Identities = 62/106 (58%), Positives = 83/106 (78%)
Frame = +1
Query: 217 QVFDVPDQPGYCLLLNKDRITAGDGVKAHDLEGKAAISNQTNAKVFEILKSAGIKTAFVK 396
+V+++ D PG LL +KD+ITAG+ + + LEGKAAISN+ + +F++L+ AGIKTAF K
Sbjct: 23 EVYELLDSPGKVLLQSKDQITAGNAARKNHLEGKAAISNKITSCIFQLLQEAGIKTAFTK 82
Query: 397 IASETAFLSKKCEMIPIEWVTRRLATGSFLKRNPGVPEGFRVHSSK 534
ETAF++ KCEMIPIEWV RR+ATGSFLKRNPGV EG++ + K
Sbjct: 83 KCGETAFIAPKCEMIPIEWVCRRIATGSFLKRNPGVKEGYKFYPPK 128
Score = 83.4 bits (197), Expect = 7e-15
Identities = 39/59 (66%), Positives = 46/59 (77%)
Frame = +2
Query: 521 FTPPKQETFFKDDANHDPQWSEEQIISAKFNYNGLLIGRDEVDYMRKATILIFEILGES 697
F PPK E FFKDDAN+DPQWSEEQ+I+A F + GL+IG+ EVD M AT IFEIL +S
Sbjct: 124 FYPPKVEMFFKDDANNDPQWSEEQLIAANFCFAGLVIGQTEVDIMSHATQAIFEILEKS 182
Score = 63.7 bits (148), Expect = 6e-09
Identities = 28/46 (60%), Positives = 34/46 (73%), Gaps = 1/46 (2%)
Frame = +3
Query: 690 EKAWALRDCALIDMKIXFGVDT-EGXIVLXDVIDSDSWRLWPXXDK 824
EK+W ++C L+DMKI FGVD IVL DVID+DSWRLWP D+
Sbjct: 180 EKSWLPQNCTLVDMKIEFGVDVITREIVLADVIDNDSWRLWPSGDR 225
>UniRef50_P22234 Cluster: Multifunctional protein ADE2 [Includes:
Phosphoribosylaminoimidazole- succinocarboxamide
synthase (EC 6.3.2.6) (SAICAR synthetase);
Phosphoribosylaminoimidazole carboxylase (EC 4.1.1.21)
(AIR carboxylase) (AIRC)]; n=60; Eumetazoa|Rep:
Multifunctional protein ADE2 [Includes:
Phosphoribosylaminoimidazole- succinocarboxamide
synthase (EC 6.3.2.6) (SAICAR synthetase);
Phosphoribosylaminoimidazole carboxylase (EC 4.1.1.21)
(AIR carboxylase) (AIRC)] - Homo sapiens (Human)
Length = 425
Score = 134 bits (325), Expect = 2e-30
Identities = 60/106 (56%), Positives = 83/106 (78%)
Frame = +1
Query: 217 QVFDVPDQPGYCLLLNKDRITAGDGVKAHDLEGKAAISNQTNAKVFEILKSAGIKTAFVK 396
+V+++ D PG LL +KD+ITAG+ + + LEGKAAISN+ + +F++L+ AGIKTAF +
Sbjct: 20 EVYELLDSPGKVLLQSKDQITAGNAARKNHLEGKAAISNKITSCIFQLLQEAGIKTAFTR 79
Query: 397 IASETAFLSKKCEMIPIEWVTRRLATGSFLKRNPGVPEGFRVHSSK 534
ETAF++ +CEMIPIEWV RR+ATGSFLKRNPGV EG++ + K
Sbjct: 80 KCGETAFIAPQCEMIPIEWVCRRIATGSFLKRNPGVKEGYKFYPPK 125
Score = 86.6 bits (205), Expect = 7e-16
Identities = 41/59 (69%), Positives = 47/59 (79%)
Frame = +2
Query: 521 FTPPKQETFFKDDANHDPQWSEEQIISAKFNYNGLLIGRDEVDYMRKATILIFEILGES 697
F PPK E FFKDDAN+DPQWSEEQ+I+AKF + GLLIG+ EVD M AT IFEIL +S
Sbjct: 121 FYPPKVELFFKDDANNDPQWSEEQLIAAKFCFAGLLIGQTEVDIMSHATQAIFEILEKS 179
Score = 65.7 bits (153), Expect = 1e-09
Identities = 29/46 (63%), Positives = 35/46 (76%), Gaps = 1/46 (2%)
Frame = +3
Query: 690 EKAWALRDCALIDMKIXFGVD-TEGXIVLXDVIDSDSWRLWPXXDK 824
EK+W ++C L+DMKI FGVD T IVL DVID+DSWRLWP D+
Sbjct: 177 EKSWLPQNCTLVDMKIEFGVDVTTKEIVLADVIDNDSWRLWPSGDR 222
>UniRef50_A5UWC5 Cluster:
Phosphoribosylaminoimidazolesuccinocarboxamide synthase;
n=5; Chloroflexi (class)|Rep:
Phosphoribosylaminoimidazolesuccinocarboxamide synthase
- Roseiflexus sp. RS-1
Length = 249
Score = 97.5 bits (232), Expect = 4e-19
Identities = 44/100 (44%), Positives = 64/100 (64%)
Frame = +1
Query: 220 VFDVPDQPGYCLLLNKDRITAGDGVKAHDLEGKAAISNQTNAKVFEILKSAGIKTAFVKI 399
V+ P P ++++KD I+AGDG + H + GK A+S +T A VF +L AG+ T FV
Sbjct: 15 VYAHPTDPTLAIIVHKDGISAGDGARRHTIPGKGALSGRTTANVFTMLNRAGVATHFVAA 74
Query: 400 ASETAFLSKKCEMIPIEWVTRRLATGSFLKRNPGVPEGFR 519
+ + +C MIP+E V RR+ATGS+++RNP V EG R
Sbjct: 75 PEPSVMVVYRCAMIPLEVVNRRIATGSYIRRNPDVAEGTR 114
Score = 63.7 bits (148), Expect = 6e-09
Identities = 26/49 (53%), Positives = 35/49 (71%)
Frame = +3
Query: 690 EKAWALRDCALIDMKIXFGVDTEGXIVLXDVIDSDSWRLWPXXDKDXWL 836
E+AWA +D L D+KI FG DT G +++ DVID+DSWR+WP K+ L
Sbjct: 165 EEAWAAQDVVLCDLKIEFGRDTSGRLLVADVIDNDSWRIWPGGVKERML 213
Score = 39.5 bits (88), Expect = 0.11
Identities = 21/59 (35%), Positives = 32/59 (54%)
Frame = +2
Query: 521 FTPPKQETFFKDDANHDPQWSEEQIISAKFNYNGLLIGRDEVDYMRKATILIFEILGES 697
F PP E F KDDA HDPQ + ++II+ + DEV+ M + +F ++ E+
Sbjct: 115 FDPPLLEFFLKDDARHDPQMTPDEIIAQG------IASADEVEQMASESRRVFLLIEEA 167
>UniRef50_Q6NRP1 Cluster: LOC431975 protein; n=2; Xenopus|Rep:
LOC431975 protein - Xenopus laevis (African clawed frog)
Length = 371
Score = 91.1 bits (216), Expect = 3e-17
Identities = 46/106 (43%), Positives = 67/106 (63%)
Frame = +1
Query: 217 QVFDVPDQPGYCLLLNKDRITAGDGVKAHDLEGKAAISNQTNAKVFEILKSAGIKTAFVK 396
+V+++ +QPG L+ +KD I A + KA++SN+ ++VF +L+ AGIKTAFVK
Sbjct: 95 EVYELSEQPGCVLIQSKDHINAQYTAWDGHKDTKASVSNKATSRVFILLQEAGIKTAFVK 154
Query: 397 IASETAFLSKKCEMIPIEWVTRRLATGSFLKRNPGVPEGFRVHSSK 534
SE AF++ +CEMIPIEW R++ TG RN EG+R K
Sbjct: 155 RCSEAAFIATQCEMIPIEWFCRKIPTG----RNTETDEGYRFSQPK 196
Score = 51.6 bits (118), Expect = 3e-05
Identities = 24/55 (43%), Positives = 29/55 (52%)
Frame = +3
Query: 690 EKAWALRDCALIDMKIXFGVDTEGXIVLXDVIDSDSWRLWPXXDKDXWLXNRCTG 854
EKAW +DC L+DM+I FGVD +L I S LWP +K N C G
Sbjct: 247 EKAWRAQDCTLVDMRIKFGVDVTKKEILLTDIKCGSQALWPLGNKSQLNNNPCLG 301
Score = 50.0 bits (114), Expect = 8e-05
Identities = 28/57 (49%), Positives = 39/57 (68%), Gaps = 1/57 (1%)
Frame = +2
Query: 521 FTPPKQETFFKDD-ANHDPQWSEEQIISAKFNYNGLLIGRDEVDYMRKATILIFEIL 688
F+ PK E + DD +NH Q S+EQ+++ K GLLIG+ EVD M ++TI IFEI+
Sbjct: 192 FSQPKVEMYKVDDTSNH--QLSKEQLMAVKLICAGLLIGKMEVDVMTRSTIAIFEII 246
>UniRef50_Q5FIU8 Cluster:
Phosphoribosylaminoimidazole-succinocarboxamidesynthase;
n=6; Lactobacillus|Rep:
Phosphoribosylaminoimidazole-succinocarboxamidesynthase
- Lactobacillus acidophilus
Length = 238
Score = 76.6 bits (180), Expect = 8e-13
Identities = 40/93 (43%), Positives = 55/93 (59%)
Frame = +1
Query: 235 DQPGYCLLLNKDRITAGDGVKAHDLEGKAAISNQTNAKVFEILKSAGIKTAFVKIASETA 414
D P ++ D+ TAG+G K D + KA ++N+ + +FE L GI T F+K S+T
Sbjct: 17 DDPEVLRVVYTDQATAGNGEKKDDFKNKAYLNNEISTLIFEYLAKNGIPTHFIKKISDTE 76
Query: 415 FLSKKCEMIPIEWVTRRLATGSFLKRNPGVPEG 513
L KKCEM P+E VTR +A G F R G+ EG
Sbjct: 77 ELVKKCEMFPLEVVTRNIAAGHFSSRY-GMGEG 108
Score = 37.5 bits (83), Expect = 0.45
Identities = 15/36 (41%), Positives = 21/36 (58%)
Frame = +3
Query: 720 LIDMKIXFGVDTEGXIVLXDVIDSDSWRLWPXXDKD 827
L+D K+ FG D +G I+L D D+ RLW K+
Sbjct: 171 LVDFKLEFGKDADGNIILADEFSPDNCRLWDKKTKE 206
>UniRef50_Q4J8G0 Cluster:
Phosphoribosylaminoimidazole-succinocarboxamide
synthase; n=4; Sulfolobaceae|Rep:
Phosphoribosylaminoimidazole-succinocarboxamide synthase
- Sulfolobus acidocaldarius
Length = 235
Score = 74.9 bits (176), Expect = 2e-12
Identities = 39/91 (42%), Positives = 56/91 (61%)
Frame = +1
Query: 241 PGYCLLLNKDRITAGDGVKAHDLEGKAAISNQTNAKVFEILKSAGIKTAFVKIASETAFL 420
P + LL KD ITAGDG + +L GK ++ QT+A F +L+ I+T +V + E +
Sbjct: 19 PEHYLLRFKDSITAGDGARKDELPGKGTLNAQTSALFFRLLEKNDIRTHYVGMYDEKTMI 78
Query: 421 SKKCEMIPIEWVTRRLATGSFLKRNPGVPEG 513
K +MIP+E V R +ATGS +KR P + EG
Sbjct: 79 VTKLKMIPVEVVLRNIATGSIVKRLP-IKEG 108
>UniRef50_Q49WJ0 Cluster:
Phosphoribosylaminoimidazole-succinocarboxamide
synthase; n=1; Staphylococcus saprophyticus subsp.
saprophyticus ATCC 15305|Rep:
Phosphoribosylaminoimidazole-succinocarboxamide synthase
- Staphylococcus saprophyticus subsp. saprophyticus
(strain ATCC 15305 /DSM 20229)
Length = 233
Score = 70.5 bits (165), Expect = 5e-11
Identities = 32/76 (42%), Positives = 48/76 (63%)
Frame = +1
Query: 265 KDRITAGDGVKAHDLEGKAAISNQTNAKVFEILKSAGIKTAFVKIASETAFLSKKCEMIP 444
KD +TAG+G K +EGK ++NQ +++F LK+ G+ + F++ SET L E+IP
Sbjct: 26 KDEVTAGNGAKKDFIEGKGRLNNQITSRIFNYLKAKGLNSHFIEQISETEQLVNSVEIIP 85
Query: 445 IEWVTRRLATGSFLKR 492
+E V R +A GS KR
Sbjct: 86 LEVVVRNIAAGSITKR 101
Score = 35.1 bits (77), Expect = 2.4
Identities = 15/30 (50%), Positives = 19/30 (63%)
Frame = +3
Query: 720 LIDMKIXFGVDTEGXIVLXDVIDSDSWRLW 809
L+D KI FG EG I+L D I D+ R+W
Sbjct: 170 LVDFKIEFGRTNEGEILLADEISPDTCRIW 199
>UniRef50_Q7M9X5 Cluster:
Phosphoribosylaminoimidazole-succinocarboxamide
synthase; n=18; Bacteria|Rep:
Phosphoribosylaminoimidazole-succinocarboxamide synthase
- Wolinella succinogenes
Length = 236
Score = 67.7 bits (158), Expect = 4e-10
Identities = 36/83 (43%), Positives = 53/83 (63%)
Frame = +1
Query: 265 KDRITAGDGVKAHDLEGKAAISNQTNAKVFEILKSAGIKTAFVKIASETAFLSKKCEMIP 444
KD +TA + K + GK A++ Q + ++F++L++ GIKT F+K E L K+ +IP
Sbjct: 29 KDDLTAFNAEKKGNEAGKGALNCQISTEIFKLLEAEGIKTHFIKQLDEKNMLCKRVSIIP 88
Query: 445 IEWVTRRLATGSFLKRNPGVPEG 513
IE VTR +ATGS KR G+ EG
Sbjct: 89 IEVVTRNIATGSLSKR-LGIKEG 110
Score = 37.5 bits (83), Expect = 0.45
Identities = 16/30 (53%), Positives = 19/30 (63%)
Frame = +3
Query: 720 LIDMKIXFGVDTEGXIVLXDVIDSDSWRLW 809
L+D K+ FG D EG I+L D I DS R W
Sbjct: 174 LVDFKLEFGKDIEGNILLADEISPDSCRFW 203
>UniRef50_Q7V5X1 Cluster:
Phosphoribosylaminoimidazole-succinocarboxamide
synthase; n=15; Bacteria|Rep:
Phosphoribosylaminoimidazole-succinocarboxamide synthase
- Prochlorococcus marinus (strain MIT 9313)
Length = 242
Score = 66.9 bits (156), Expect = 6e-10
Identities = 33/88 (37%), Positives = 56/88 (63%)
Frame = +1
Query: 235 DQPGYCLLLNKDRITAGDGVKAHDLEGKAAISNQTNAKVFEILKSAGIKTAFVKIASETA 414
DQP L+ K+ TA + +K +LEGK ++ Q +A++FE+L+ G+ T ++ + SET
Sbjct: 21 DQPDRVLVEFKNDATAFNALKRAELEGKGRLNCQISARLFEMLEREGVPTHYLDLVSETW 80
Query: 415 FLSKKCEMIPIEWVTRRLATGSFLKRNP 498
L + ++IP+E V R +ATGS ++ P
Sbjct: 81 MLVQHVDVIPLEVVIRNVATGSLCQQTP 108
Score = 34.3 bits (75), Expect = 4.2
Identities = 13/39 (33%), Positives = 23/39 (58%)
Frame = +3
Query: 711 DCALIDMKIXFGVDTEGXIVLXDVIDSDSWRLWPXXDKD 827
D L+D K+ G+++ G +++ D I D+ RLW + D
Sbjct: 172 DLLLVDFKLELGLNSAGTLLVADEISPDTCRLWDHRNSD 210
>UniRef50_Q87Y59 Cluster:
Phosphoribosylaminoimidazole-succinocarboxamide
synthase; n=12; Gammaproteobacteria|Rep:
Phosphoribosylaminoimidazole-succinocarboxamide synthase
- Pseudomonas syringae pv. tomato
Length = 236
Score = 65.7 bits (153), Expect = 1e-09
Identities = 35/97 (36%), Positives = 56/97 (57%)
Frame = +1
Query: 235 DQPGYCLLLNKDRITAGDGVKAHDLEGKAAISNQTNAKVFEILKSAGIKTAFVKIASETA 414
D +LL ++ +A DG + L+ K ++N+ NA + + L+ AGI T F K+ +
Sbjct: 19 DDADRLILLFRNDTSAFDGKRIEQLDRKGTVNNKFNAFIMQKLEEAGIPTQFDKLLGDNE 78
Query: 415 FLSKKCEMIPIEWVTRRLATGSFLKRNPGVPEGFRVH 525
L KK +MIP+E V R A GS +KR G+ EG +++
Sbjct: 79 CLVKKLDMIPVECVVRNYAAGSLVKR-LGIEEGTKLN 114
>UniRef50_Q58987 Cluster:
Phosphoribosylaminoimidazole-succinocarboxamide
synthase; n=5; Euryarchaeota|Rep:
Phosphoribosylaminoimidazole-succinocarboxamide synthase
- Methanococcus jannaschii
Length = 242
Score = 65.7 bits (153), Expect = 1e-09
Identities = 34/94 (36%), Positives = 58/94 (61%), Gaps = 1/94 (1%)
Frame = +1
Query: 220 VFDVPDQPGYCLLLNKDRITAGDGVKAHDL-EGKAAISNQTNAKVFEILKSAGIKTAFVK 396
++++ D L+ +D ITAG+G K HD+ +GK ++ ++K+FE L+ G+KT ++K
Sbjct: 22 IYEIDDDK--VLIEFRDDITAGNGAK-HDVKQGKGYLNALISSKLFEALEENGVKTHYIK 78
Query: 397 IASETAFLSKKCEMIPIEWVTRRLATGSFLKRNP 498
++KK E+IPIE + R +A GS +R P
Sbjct: 79 YIEPRYMIAKKVEIIPIEVIVRNIAAGSLCRRYP 112
Score = 36.3 bits (80), Expect = 1.0
Identities = 15/36 (41%), Positives = 21/36 (58%)
Frame = +3
Query: 720 LIDMKIXFGVDTEGXIVLXDVIDSDSWRLWPXXDKD 827
L+D KI G D EG +++ D I D+ RLW +D
Sbjct: 179 LVDFKIEIGKDREGNLLVADEISPDTMRLWDKETRD 214
>UniRef50_Q8TIS9 Cluster:
Phosphoribosylaminoimidazole-succinocarboxamide
synthase; n=8; cellular organisms|Rep:
Phosphoribosylaminoimidazole-succinocarboxamide synthase
- Methanosarcina acetivorans
Length = 237
Score = 65.7 bits (153), Expect = 1e-09
Identities = 33/88 (37%), Positives = 53/88 (60%)
Frame = +1
Query: 235 DQPGYCLLLNKDRITAGDGVKAHDLEGKAAISNQTNAKVFEILKSAGIKTAFVKIASETA 414
D P + ++ +TA +G K ++E K + Q + K+FE+L+++GIKT FV + S+
Sbjct: 18 DNPDTLIAEFRNSLTAFNGEKKGEMEKKGYYNAQISKKIFEMLEASGIKTHFVSMLSDIE 77
Query: 415 FLSKKCEMIPIEWVTRRLATGSFLKRNP 498
L KK E+I IE + R +A GS K+ P
Sbjct: 78 MLVKKVEIIKIEVIVRNIAAGSITKKYP 105
>UniRef50_Q8G5A9 Cluster:
Phosphoribosylaminoimidazole-succinocarboxamide
synthase; n=5; Bacteria|Rep:
Phosphoribosylaminoimidazole-succinocarboxamide synthase
- Bifidobacterium longum
Length = 250
Score = 64.5 bits (150), Expect = 3e-09
Identities = 35/93 (37%), Positives = 48/93 (51%)
Frame = +1
Query: 235 DQPGYCLLLNKDRITAGDGVKAHDLEGKAAISNQTNAKVFEILKSAGIKTAFVKIASETA 414
D P + K+ TAGDG K D GK ++N +F++LK GI + +K +T
Sbjct: 19 DDPEVLWVEYKNTATAGDGEKKEDFTGKGRLNNLITTIIFDLLKKRGIDSHLIKRVDDTG 78
Query: 415 FLSKKCEMIPIEWVTRRLATGSFLKRNPGVPEG 513
L +K M P+E V R +A G F R GV EG
Sbjct: 79 QLVRKVNMFPLEIVLRNVAAGHFCSR-LGVEEG 110
Score = 36.7 bits (81), Expect = 0.79
Identities = 17/37 (45%), Positives = 21/37 (56%)
Frame = +3
Query: 711 DCALIDMKIXFGVDTEGXIVLXDVIDSDSWRLWPXXD 821
D L+D KI G T+G ++L D I DS RLW D
Sbjct: 170 DVKLVDFKIEMGRATDGTLLLADEITPDSCRLWDQKD 206
>UniRef50_P12046 Cluster:
Phosphoribosylaminoimidazole-succinocarboxamide
synthase; n=61; Bacilli|Rep:
Phosphoribosylaminoimidazole-succinocarboxamide synthase
- Bacillus subtilis
Length = 241
Score = 63.3 bits (147), Expect = 8e-09
Identities = 33/93 (35%), Positives = 53/93 (56%)
Frame = +1
Query: 235 DQPGYCLLLNKDRITAGDGVKAHDLEGKAAISNQTNAKVFEILKSAGIKTAFVKIASETA 414
D ++ KD TA +G K ++ GK ++N+ ++ +F+ L + GI F++ SET
Sbjct: 21 DDENTLYVVYKDSATAFNGEKKAEISGKGRLNNEISSLIFKHLHAKGINNHFIERISETE 80
Query: 415 FLSKKCEMIPIEWVTRRLATGSFLKRNPGVPEG 513
L KK ++P+E V R + GS KR G+PEG
Sbjct: 81 QLIKKVTIVPLEVVVRNVVAGSMSKR-LGIPEG 112
Score = 39.9 bits (89), Expect = 0.084
Identities = 18/35 (51%), Positives = 23/35 (65%), Gaps = 2/35 (5%)
Frame = +3
Query: 711 DC--ALIDMKIXFGVDTEGXIVLXDVIDSDSWRLW 809
DC LID K+ FG+D EG ++L D I D+ RLW
Sbjct: 170 DCHVRLIDFKLEFGLDAEGQVLLADEISPDTCRLW 204
>UniRef50_P0A7E0 Cluster:
Phosphoribosylaminoimidazole-succinocarboxamide
synthase; n=50; Proteobacteria|Rep:
Phosphoribosylaminoimidazole-succinocarboxamide synthase
- Shigella flexneri
Length = 237
Score = 62.5 bits (145), Expect = 1e-08
Identities = 32/97 (32%), Positives = 53/97 (54%)
Frame = +1
Query: 235 DQPGYCLLLNKDRITAGDGVKAHDLEGKAAISNQTNAKVFEILKSAGIKTAFVKIASETA 414
+ P +L ++ +AGDG + + K ++N+ N + L AGI T ++ S+T
Sbjct: 19 ENPDLLVLEFRNDTSAGDGARIEQFDRKGMVNNKFNYFIMSKLAEAGIPTQMERLLSDTE 78
Query: 415 FLSKKCEMIPIEWVTRRLATGSFLKRNPGVPEGFRVH 525
L KK +M+P+E V R A GS +KR G+ EG ++
Sbjct: 79 CLVKKLDMVPVECVVRNRAAGSLVKR-LGIEEGIELN 114
>UniRef50_Q8ES99 Cluster:
Phosphoribosylaminoimidazole-succinocarboxamide
synthase; n=10; Firmicutes|Rep:
Phosphoribosylaminoimidazole-succinocarboxamide synthase
- Oceanobacillus iheyensis
Length = 237
Score = 62.5 bits (145), Expect = 1e-08
Identities = 33/92 (35%), Positives = 51/92 (55%)
Frame = +1
Query: 217 QVFDVPDQPGYCLLLNKDRITAGDGVKAHDLEGKAAISNQTNAKVFEILKSAGIKTAFVK 396
+V+ + +L K+ TA +G K EGK ++N+ ++ +F+ L AGI T F+K
Sbjct: 13 KVYQSSEDEHQLVLSYKNDATAFNGEKKSQFEGKGRLNNEISSLIFQRLHEAGISTHFIK 72
Query: 397 IASETAFLSKKCEMIPIEWVTRRLATGSFLKR 492
T + +K +IP+E V R LATGS KR
Sbjct: 73 RLDSTQQIVQKTSIIPLEVVIRNLATGSITKR 104
Score = 33.9 bits (74), Expect = 5.5
Identities = 13/30 (43%), Positives = 20/30 (66%)
Frame = +3
Query: 720 LIDMKIXFGVDTEGXIVLXDVIDSDSWRLW 809
L+D K+ FG + +G I+L D + D+ RLW
Sbjct: 173 LVDFKLEFGRNKDGEILLSDEVSPDTCRLW 202
>UniRef50_O57978 Cluster:
Phosphoribosylaminoimidazole-succinocarboxamide
synthase; n=6; cellular organisms|Rep:
Phosphoribosylaminoimidazole-succinocarboxamide synthase
- Pyrococcus horikoshii
Length = 238
Score = 62.1 bits (144), Expect = 2e-08
Identities = 32/86 (37%), Positives = 49/86 (56%)
Frame = +1
Query: 265 KDRITAGDGVKAHDLEGKAAISNQTNAKVFEILKSAGIKTAFVKIASETAFLSKKCEMIP 444
KD TA DG K +GK ++ Q + F++L+ GIKT F+ +A + +K +M P
Sbjct: 28 KDDATAFDGTKKARFKGKGWLNAQLSVIFFKLLEEHGIKTHFIGVAGGNRLIVEKLDMYP 87
Query: 445 IEWVTRRLATGSFLKRNPGVPEGFRV 522
+E V R + GS KR P +PEG+ +
Sbjct: 88 LEVVVRNVVAGSLKKRLP-LPEGYEL 112
Score = 36.3 bits (80), Expect = 1.0
Identities = 17/41 (41%), Positives = 21/41 (51%)
Frame = +3
Query: 702 ALRDCALIDMKIXFGVDTEGXIVLXDVIDSDSWRLWPXXDK 824
A + L+D K+ FG D G IVL D I D+ R W K
Sbjct: 165 AKKGIILVDFKLEFGKDKNGDIVLADEISPDTCRFWDAKTK 205
>UniRef50_Q92AN6 Cluster:
Phosphoribosylaminoimidazole-succinocarboxamide
synthase; n=17; Bacteria|Rep:
Phosphoribosylaminoimidazole-succinocarboxamide synthase
- Listeria innocua
Length = 237
Score = 61.3 bits (142), Expect = 3e-08
Identities = 31/86 (36%), Positives = 46/86 (53%)
Frame = +1
Query: 235 DQPGYCLLLNKDRITAGDGVKAHDLEGKAAISNQTNAKVFEILKSAGIKTAFVKIASETA 414
D+ G + KD TA +GV+ GK ++NQ + +F L GI + F++ SET
Sbjct: 18 DEAGVLRVAYKDDATALNGVRKESFAGKGELNNQITSLIFSYLAKEGISSHFIRAISETE 77
Query: 415 FLSKKCEMIPIEWVTRRLATGSFLKR 492
L K+ +IP+E V R + GS KR
Sbjct: 78 QLVKEVSIIPLEVVVRNVMAGSLAKR 103
Score = 35.9 bits (79), Expect = 1.4
Identities = 16/30 (53%), Positives = 19/30 (63%)
Frame = +3
Query: 720 LIDMKIXFGVDTEGXIVLXDVIDSDSWRLW 809
LID K+ FG D G I+L D I D+ RLW
Sbjct: 172 LIDFKLEFGRDAAGNILLADEISPDTCRLW 201
>UniRef50_Q466M0 Cluster: Phosphoribosylaminoimidazole carboxylase,
phosphoribosylaminoribosylaminoimidazole
succinocarboxamide synthetase; n=3; Archaea|Rep:
Phosphoribosylaminoimidazole carboxylase,
phosphoribosylaminoribosylaminoimidazole
succinocarboxamide synthetase - Methanosarcina barkeri
(strain Fusaro / DSM 804)
Length = 296
Score = 60.5 bits (140), Expect = 6e-08
Identities = 28/81 (34%), Positives = 44/81 (54%)
Frame = +1
Query: 256 LLNKDRITAGDGVKAHDLEGKAAISNQTNAKVFEILKSAGIKTAFVKIASETAFLSKKCE 435
L ++ +T GD + + G A +F +L G+ TAF++ S L +CE
Sbjct: 22 LETRNVLTGGDAARRETIAGIGIHKTTQAANIFSLLNRKGLPTAFIERTSPNTLLCYQCE 81
Query: 436 MIPIEWVTRRLATGSFLKRNP 498
M+P+E V RR A GS+L+R+P
Sbjct: 82 MLPLELVVRRYAWGSYLQRHP 102
Score = 40.3 bits (90), Expect = 0.064
Identities = 18/44 (40%), Positives = 27/44 (61%), Gaps = 1/44 (2%)
Frame = +3
Query: 720 LIDMKIXFGVDTEGX-IVLXDVIDSDSWRLWPXXDKDXWLXNRC 848
L+D+KI G + IV+ DVID+DSWR+W + + L +C
Sbjct: 229 LVDLKIEVGRRLDNNRIVIADVIDNDSWRIWSGGNPEKQLDKQC 272
>UniRef50_Q8TX83 Cluster:
Phosphoribosylaminoimidazole-succinocarboxamide
synthase; n=6; cellular organisms|Rep:
Phosphoribosylaminoimidazole-succinocarboxamide synthase
- Methanopyrus kandleri
Length = 247
Score = 60.5 bits (140), Expect = 6e-08
Identities = 29/93 (31%), Positives = 56/93 (60%)
Frame = +1
Query: 220 VFDVPDQPGYCLLLNKDRITAGDGVKAHDLEGKAAISNQTNAKVFEILKSAGIKTAFVKI 399
+++ P+ ++ +D ITA + K +EGK + +A++FE+L+ AGI T +V++
Sbjct: 15 LYEHPEDENLLVMEFRDDITAFNMEKMDTVEGKGVYNCLISARLFEVLEDAGIPTHYVEL 74
Query: 400 ASETAFLSKKCEMIPIEWVTRRLATGSFLKRNP 498
A E + ++ +M +E + R +ATGS ++R P
Sbjct: 75 ADERRMVVERLDMFNLEVICRNMATGSLVERLP 107
Score = 37.9 bits (84), Expect = 0.34
Identities = 16/37 (43%), Positives = 24/37 (64%), Gaps = 2/37 (5%)
Frame = +3
Query: 705 LRDC--ALIDMKIXFGVDTEGXIVLXDVIDSDSWRLW 809
L+DC L+D K+ FGV+ +G +V+ D I D+ R W
Sbjct: 167 LKDCDIILVDFKLEFGVNPDGEVVVGDEISPDTCRFW 203
>UniRef50_Q8ZCD2 Cluster:
Phosphoribosylaminoimidazole-succinocarboxamide
synthase; n=17; Enterobacteriaceae|Rep:
Phosphoribosylaminoimidazole-succinocarboxamide synthase
- Yersinia pestis
Length = 237
Score = 59.3 bits (137), Expect = 1e-07
Identities = 33/97 (34%), Positives = 53/97 (54%)
Frame = +1
Query: 235 DQPGYCLLLNKDRITAGDGVKAHDLEGKAAISNQTNAKVFEILKSAGIKTAFVKIASETA 414
+ P +L ++ +A DG + + K ++N+ N + L+ AGI T ++ S+T
Sbjct: 19 ENPDLLVLEFRNDTSALDGQRIEQFDRKGMVNNKFNHFIMTKLEEAGIPTQMERLLSDTE 78
Query: 415 FLSKKCEMIPIEWVTRRLATGSFLKRNPGVPEGFRVH 525
L KK EMIP+E V R A GS +KR G+ EG ++
Sbjct: 79 VLVKKLEMIPVECVIRNRAAGSLVKR-LGIEEGLSLN 114
>UniRef50_Q9X0X0 Cluster:
Phosphoribosylaminoimidazole-succinocarboxamide
synthase; n=4; Thermotogaceae|Rep:
Phosphoribosylaminoimidazole-succinocarboxamide synthase
- Thermotoga maritima
Length = 230
Score = 57.6 bits (133), Expect = 4e-07
Identities = 34/85 (40%), Positives = 44/85 (51%)
Frame = +1
Query: 247 YCLLLNKDRITAGDGVKAHDLEGKAAISNQTNAKVFEILKSAGIKTAFVKIASETAFLSK 426
Y LL KD ITAGDG+K L GK +I +T A + + L GIKT V+
Sbjct: 16 YALLEFKDDITAGDGLKHDVLTGKGSICAETTAILMKYLSEKGIKTHLVEYIPPRTLKVI 75
Query: 427 KCEMIPIEWVTRRLATGSFLKRNPG 501
+M P+E V R GSF++R G
Sbjct: 76 PLKMFPLEVVVRLKKAGSFVRRYGG 100
>UniRef50_UPI00015BB105 Cluster:
phosphoribosylaminoimidazole-succinocarboxamide
synthase; n=1; Ignicoccus hospitalis KIN4/I|Rep:
phosphoribosylaminoimidazole-succinocarboxamide synthase
- Ignicoccus hospitalis KIN4/I
Length = 235
Score = 57.2 bits (132), Expect = 5e-07
Identities = 33/102 (32%), Positives = 59/102 (57%)
Frame = +1
Query: 217 QVFDVPDQPGYCLLLNKDRITAGDGVKAHDLEGKAAISNQTNAKVFEILKSAGIKTAFVK 396
+V+D+ D+ LL KD TA DG K +++GK ++ + + + L+ G+KT F+
Sbjct: 11 KVYDMDDK---VLLKFKDVFTAFDGKKVEEVKGKGKVNAEFTELLMKYLEQHGVKTHFLS 67
Query: 397 IASETAFLSKKCEMIPIEWVTRRLATGSFLKRNPGVPEGFRV 522
+E ++ K + +P+E++ R A GS LKR P + +G R+
Sbjct: 68 -RNEDEIVAIKTKPLPLEFIVRNYAYGSLLKRLPILEKGQRL 108
>UniRef50_A4M8A0 Cluster:
Phosphoribosylaminoimidazole-succinocarboxamide
synthase; n=1; Petrotoga mobilis SJ95|Rep:
Phosphoribosylaminoimidazole-succinocarboxamide synthase
- Petrotoga mobilis SJ95
Length = 238
Score = 55.6 bits (128), Expect = 2e-06
Identities = 28/83 (33%), Positives = 47/83 (56%)
Frame = +1
Query: 265 KDRITAGDGVKAHDLEGKAAISNQTNAKVFEILKSAGIKTAFVKIASETAFLSKKCEMIP 444
KD +TA +G+K + K I+ + + FE+L + GI T ++ E +F++K ++IP
Sbjct: 31 KDDVTAFNGLKKDQILNKGKINKEISKFFFEMLNNQGINTHYINDYDENSFVAKWTDLIP 90
Query: 445 IEWVTRRLATGSFLKRNPGVPEG 513
+E + R G F KR GV +G
Sbjct: 91 LEVIIRNYTAGGFCKRY-GVKKG 112
>UniRef50_Q98NM8 Cluster:
Phosphoribosylaminoimidazole-succinocarboxamide synthase
1; n=116; Bacteria|Rep:
Phosphoribosylaminoimidazole-succinocarboxamide synthase
1 - Rhizobium loti (Mesorhizobium loti)
Length = 264
Score = 55.6 bits (128), Expect = 2e-06
Identities = 32/92 (34%), Positives = 50/92 (54%)
Frame = +1
Query: 238 QPGYCLLLNKDRITAGDGVKAHDLEGKAAISNQTNAKVFEILKSAGIKTAFVKIASETAF 417
+PG + KD TA + K ++GK ++N+ + +F L GI T F++ +
Sbjct: 20 EPGTLIQFFKDDATAFNKKKHEVVDGKGVLNNRISEHIFNHLNRMGIPTHFIRRLNMREQ 79
Query: 418 LSKKCEMIPIEWVTRRLATGSFLKRNPGVPEG 513
L K+ E+IP+E V R +A GS KR G+ EG
Sbjct: 80 LIKEVEIIPLEVVVRNVAAGSLSKR-LGIEEG 110
>UniRef50_Q3YRB0 Cluster: SAICAR synthetase; n=2;
Anaplasmataceae|Rep: SAICAR synthetase - Ehrlichia canis
(strain Jake)
Length = 258
Score = 54.4 bits (125), Expect = 4e-06
Identities = 27/76 (35%), Positives = 45/76 (59%)
Frame = +1
Query: 265 KDRITAGDGVKAHDLEGKAAISNQTNAKVFEILKSAGIKTAFVKIASETAFLSKKCEMIP 444
KD +TA + KA + K ++N ++ + + L + GIKT F+ + ++ L KK +IP
Sbjct: 38 KDEVTAFNNKKADVINEKGIVNNYISSFLMKELTNKGIKTHFISLLNQREQLVKKVSIIP 97
Query: 445 IEWVTRRLATGSFLKR 492
+E V R L+ G+F KR
Sbjct: 98 LEIVVRNLSAGNFSKR 113
>UniRef50_Q6LZT3 Cluster:
Phosphoribosylaminoimidazole-succinocarboxamide
synthase; n=5; Methanococcus|Rep:
Phosphoribosylaminoimidazole-succinocarboxamide synthase
- Methanococcus maripaludis
Length = 246
Score = 52.8 bits (121), Expect = 1e-05
Identities = 25/94 (26%), Positives = 52/94 (55%), Gaps = 1/94 (1%)
Frame = +1
Query: 220 VFDVPDQPGYCLLLNKDRITAGDGVKAHDLE-GKAAISNQTNAKVFEILKSAGIKTAFVK 396
++ + + L+ +D ITAG+G K HD++ GK ++ + ++F +L+ + T ++
Sbjct: 23 IYKIEENEKEVLVEFRDDITAGNGAK-HDVKSGKGYLNTLISTELFNVLEKNNVPTHLIE 81
Query: 397 IASETAFLSKKCEMIPIEWVTRRLATGSFLKRNP 498
++K ++IP+E + R +A GS K+ P
Sbjct: 82 YIEPNIMIAKNVKIIPLEVIVRNIAAGSLCKKYP 115
Score = 35.5 bits (78), Expect = 1.8
Identities = 16/36 (44%), Positives = 20/36 (55%)
Frame = +3
Query: 720 LIDMKIXFGVDTEGXIVLXDVIDSDSWRLWPXXDKD 827
L+D KI G +G IV+ D I D+ RLW KD
Sbjct: 182 LVDFKIEVGKTADGQIVVADEISPDTMRLWDKETKD 217
>UniRef50_Q9RXT0 Cluster:
Phosphoribosylaminoimidazole-succinocarboxamide
synthase; n=37; cellular organisms|Rep:
Phosphoribosylaminoimidazole-succinocarboxamide synthase
- Deinococcus radiodurans
Length = 237
Score = 52.4 bits (120), Expect = 1e-05
Identities = 31/83 (37%), Positives = 46/83 (55%)
Frame = +1
Query: 265 KDRITAGDGVKAHDLEGKAAISNQTNAKVFEILKSAGIKTAFVKIASETAFLSKKCEMIP 444
KD TA + K + GK A +N A ++ L++AGI T F++ S+ K ++P
Sbjct: 29 KDDATAFNAQKRGEWAGKGATNNAITAHLYPQLEAAGIPTHFLEKLSDREQRVKAVTIVP 88
Query: 445 IEWVTRRLATGSFLKRNPGVPEG 513
+E + R +A GSF KR GV EG
Sbjct: 89 VEVIVRNVAAGSFSKR-LGVEEG 110
>UniRef50_A3H6Y2 Cluster:
Phosphoribosylaminoimidazole-succinocarboxamide
synthase; n=1; Caldivirga maquilingensis IC-167|Rep:
Phosphoribosylaminoimidazole-succinocarboxamide synthase
- Caldivirga maquilingensis IC-167
Length = 241
Score = 51.2 bits (117), Expect = 3e-05
Identities = 24/78 (30%), Positives = 39/78 (50%)
Frame = +1
Query: 265 KDRITAGDGVKAHDLEGKAAISNQTNAKVFEILKSAGIKTAFVKIASETAFLSKKCEMIP 444
KD +TA DG + GK ++ A L +G++T F+ + ++ MIP
Sbjct: 30 KDEVTALDGARKEYAPGKGKLAASQTAFFMSYLNESGVRTHFINWDGDRRIHVRRLRMIP 89
Query: 445 IEWVTRRLATGSFLKRNP 498
+E + R A GSF++R P
Sbjct: 90 VEVIVRNYAYGSFIRRMP 107
>UniRef50_Q8ZZK5 Cluster:
Phosphoribosylaminoimidazole-succinocarboxamide
synthase; n=4; Pyrobaculum|Rep:
Phosphoribosylaminoimidazole-succinocarboxamide synthase
- Pyrobaculum aerophilum
Length = 234
Score = 51.2 bits (117), Expect = 3e-05
Identities = 30/82 (36%), Positives = 45/82 (54%)
Frame = +1
Query: 265 KDRITAGDGVKAHDLEGKAAISNQTNAKVFEILKSAGIKTAFVKIASETAFLSKKCEMIP 444
KD +TAGDG GK A++ + +A +F+ L S ++T FV+ A E+IP
Sbjct: 24 KDEVTAGDGAVKAQAPGKGALTAELSALLFKYL-SRVVETHFVEYKPPNALAVIPAEVIP 82
Query: 445 IEWVTRRLATGSFLKRNPGVPE 510
+E + R A GS L+R P + E
Sbjct: 83 VEVIVRFKAYGSQLRRMPRLRE 104
>UniRef50_Q648Z8 Cluster:
Phosphoribosylaminoimidazolesuccinocarboxamide synthase;
n=1; uncultured archaeon GZfos35D7|Rep:
Phosphoribosylaminoimidazolesuccinocarboxamide synthase
- uncultured archaeon GZfos35D7
Length = 249
Score = 49.6 bits (113), Expect = 1e-04
Identities = 28/90 (31%), Positives = 43/90 (47%)
Frame = +1
Query: 226 DVPDQPGYCLLLNKDRITAGDGVKAHDLEGKAAISNQTNAKVFEILKSAGIKTAFVKIAS 405
D+ ++ G DR TA DGVK + K + + + FEIL+ AGI T F
Sbjct: 13 DIFEEDGKTFFEFTDRTTAFDGVKEDEFSHKGEVCCRLSTYWFEILEEAGIPTHFRAFVP 72
Query: 406 ETAFLSKKCEMIPIEWVTRRLATGSFLKRN 495
+ +++PIE + R GS L+R+
Sbjct: 73 PNIMEVEPLDILPIEVIWRNFVAGSILRRH 102
>UniRef50_Q88U22 Cluster:
Phosphoribosylaminoimidazole-succinocarboxamide
synthase; n=3; Lactobacillales|Rep:
Phosphoribosylaminoimidazole-succinocarboxamide synthase
- Lactobacillus plantarum
Length = 243
Score = 46.0 bits (104), Expect = 0.001
Identities = 26/80 (32%), Positives = 46/80 (57%)
Frame = +1
Query: 268 DRITAGDGVKAHDLEGKAAISNQTNAKVFEILKSAGIKTAFVKIASETAFLSKKCEMIPI 447
D+ TA +G + ++ K ++N+ + +F+ L + GI F++ S+ L ++ MIP+
Sbjct: 34 DQATALNGKRKVPIDQKGRLNNRIASLIFKDLANHGIANHFIEQPSDYVQLVRRVTMIPL 93
Query: 448 EWVTRRLATGSFLKRNPGVP 507
E V R A+GSF +R VP
Sbjct: 94 ETVVRNAASGSF-ERKFAVP 112
Score = 33.5 bits (73), Expect = 7.3
Identities = 15/29 (51%), Positives = 19/29 (65%)
Frame = +3
Query: 720 LIDMKIXFGVDTEGXIVLXDVIDSDSWRL 806
L+D KI FG+ T G ++L D I DS RL
Sbjct: 177 LVDFKIEFGLTTTGKVLLADEISPDSCRL 205
>UniRef50_Q5JD27 Cluster:
Phosphoribosylaminoimidazolesuccinocarboxamide synthase;
n=1; Thermococcus kodakarensis KOD1|Rep:
Phosphoribosylaminoimidazolesuccinocarboxamide synthase
- Pyrococcus kodakaraensis (Thermococcus kodakaraensis)
Length = 219
Score = 44.4 bits (100), Expect = 0.004
Identities = 31/99 (31%), Positives = 45/99 (45%), Gaps = 7/99 (7%)
Frame = +1
Query: 226 DVPDQPGYCLLLNKDRITAGDGVK-------AHDLEGKAAISNQTNAKVFEILKSAGIKT 384
DV + Y + KD + DG + + GK +I F +L+ GI+T
Sbjct: 11 DVYEDGPYLVFYFKDSVLGEDGREDTGGNEIVGERRGKGSIVLDETEFFFRLLEEKGIRT 70
Query: 385 AFVKIASETAFLSKKCEMIPIEWVTRRLATGSFLKRNPG 501
FV+ E + E IP+E + R LA GSFL+R G
Sbjct: 71 HFVERIDERRARFLRAERIPLEVIYRELAYGSFLRRYQG 109
>UniRef50_Q03Y92 Cluster:
Phosphoribosylaminoimidazolesuccinocarboxamide (SAICAR)
synthase; n=4; Lactobacillales|Rep:
Phosphoribosylaminoimidazolesuccinocarboxamide (SAICAR)
synthase - Leuconostoc mesenteroides subsp.
mesenteroides (strain ATCC 8293 /NCDO 523)
Length = 249
Score = 43.6 bits (98), Expect = 0.007
Identities = 26/91 (28%), Positives = 45/91 (49%)
Frame = +1
Query: 235 DQPGYCLLLNKDRITAGDGVKAHDLEGKAAISNQTNAKVFEILKSAGIKTAFVKIASETA 414
D P + D+ TA +G ++ K +++ + +FE L GI+ ++ SET
Sbjct: 30 DNPTILWVHYMDQATALNGKVHENIPEKGQLNSAISHILFEHLTRQGIENHYLSSVSETD 89
Query: 415 FLSKKCEMIPIEWVTRRLATGSFLKRNPGVP 507
L +++PIE VTR A+G F+ + P
Sbjct: 90 ELDLALDILPIEVVTRNYASGHFVSKFNATP 120
>UniRef50_A6QAA3 Cluster:
Phosphoribosylaminoimidazole-succinocarboxamide
synthase; n=2; Epsilonproteobacteria|Rep:
Phosphoribosylaminoimidazole-succinocarboxamide synthase
- Sulfurovum sp. (strain NBC37-1)
Length = 244
Score = 41.1 bits (92), Expect = 0.036
Identities = 16/37 (43%), Positives = 25/37 (67%)
Frame = +3
Query: 699 WALRDCALIDMKIXFGVDTEGXIVLXDVIDSDSWRLW 809
+A R+ L+D K+ FG D +G I+L D + D++RLW
Sbjct: 172 YAQRNLTLVDFKLEFGRDMDGNIILIDELSPDNFRLW 208
>UniRef50_P38025 Cluster:
Phosphoribosylaminoimidazole-succinocarboxamide
synthase, chloroplast precursor; n=13; cellular
organisms|Rep:
Phosphoribosylaminoimidazole-succinocarboxamide
synthase, chloroplast precursor - Arabidopsis thaliana
(Mouse-ear cress)
Length = 411
Score = 41.1 bits (92), Expect = 0.036
Identities = 27/88 (30%), Positives = 42/88 (47%)
Frame = +1
Query: 217 QVFDVPDQPGYCLLLNKDRITAGDGVKAHDLEGKAAISNQTNAKVFEILKSAGIKTAFVK 396
+V D+ D Y +L+ DR++A D A + K + N+T+ F + A V
Sbjct: 113 KVRDIYDAGDYLVLITTDRLSAFDRNLA-SIPFKGQVLNETSLWWFNNTQHI-TPNAIVS 170
Query: 397 IASETAFLSKKCEMIPIEWVTRRLATGS 480
++KKC + PIE+V R TGS
Sbjct: 171 SPDRNVVIAKKCSVFPIEFVVRGYVTGS 198
>UniRef50_P73471 Cluster:
Phosphoribosylaminoimidazole-succinocarboxamide
synthase; n=19; Bacteria|Rep:
Phosphoribosylaminoimidazole-succinocarboxamide synthase
- Synechocystis sp. (strain PCC 6803)
Length = 264
Score = 40.7 bits (91), Expect = 0.048
Identities = 18/46 (39%), Positives = 26/46 (56%)
Frame = +3
Query: 690 EKAWALRDCALIDMKIXFGVDTEGXIVLXDVIDSDSWRLWPXXDKD 827
++ +A D L+D K+ FG D +G I+L D I D+ RLW D
Sbjct: 176 QRFFAQCDITLVDFKLEFGGDRQGKIILADEISPDTCRLWDNAQAD 221
>UniRef50_Q3ET89 Cluster:
Phosphoribosylamidoimidazole-succinocarboxamide
synthase; n=1; Bacillus thuringiensis serovar
israelensis ATCC 35646|Rep:
Phosphoribosylamidoimidazole-succinocarboxamide synthase
- Bacillus thuringiensis serovar israelensis ATCC 35646
Length = 137
Score = 39.5 bits (88), Expect = 0.11
Identities = 21/57 (36%), Positives = 30/57 (52%)
Frame = +1
Query: 265 KDRITAGDGVKAHDLEGKAAISNQTNAKVFEILKSAGIKTAFVKIASETAFLSKKCE 435
KD TA +G K + GK ++N+ +F L+ GIKT V+ SET +K E
Sbjct: 48 KDSATAFNGEKKETITGKGRLNNEITTLLFRKLQEVGIKTHLVEKLSETEQTCQKSE 104
>UniRef50_Q5IWX2 Cluster: Plastid
phosphoribosylaminoimidazole-succinocarboxamide
synthase; n=1; Prototheca wickerhamii|Rep: Plastid
phosphoribosylaminoimidazole-succinocarboxamide synthase
- Prototheca wickerhamii
Length = 245
Score = 38.3 bits (85), Expect = 0.26
Identities = 29/88 (32%), Positives = 42/88 (47%)
Frame = +1
Query: 217 QVFDVPDQPGYCLLLNKDRITAGDGVKAHDLEGKAAISNQTNAKVFEILKSAGIKTAFVK 396
+V D D L++ DR +A D A + K I NQT+A E +S + A +
Sbjct: 109 KVRDTYDLGDKLLIVTTDRQSAFDRHLA-SIPFKGQILNQTSAWWMEATRSI-VPNALLG 166
Query: 397 IASETAFLSKKCEMIPIEWVTRRLATGS 480
+ A L KC + P+E+V R TGS
Sbjct: 167 LPDPNASLMTKCTVFPVEFVCRGYMTGS 194
>UniRef50_A1G3E0 Cluster: SAICAR synthetase; n=1; Salinispora
arenicola CNS205|Rep: SAICAR synthetase - Salinispora
arenicola CNS205
Length = 236
Score = 35.5 bits (78), Expect = 1.8
Identities = 23/95 (24%), Positives = 43/95 (45%)
Frame = +1
Query: 238 QPGYCLLLNKDRITAGDGVKAHDLEGKAAISNQTNAKVFEILKSAGIKTAFVKIASETAF 417
+PG C++ + + + ++G A + V +L AG+ T F + +
Sbjct: 24 EPGRCVVEMIPSLRSFTHDRDELMDGTAELRLDFFEYVSGVLAKAGVPTVFRERLGPITY 83
Query: 418 LSKKCEMIPIEWVTRRLATGSFLKRNPGVPEGFRV 522
L+ +P E + + ATGS ++ PG+ E RV
Sbjct: 84 LADYRPAVPFEVIVKNRATGSTTRKYPGLFEEGRV 118
>UniRef50_Q4UML8 Cluster:
Phosphoribosylaminoimidazole-succinocarboxamide
synthase; n=8; Rickettsia|Rep:
Phosphoribosylaminoimidazole-succinocarboxamide synthase
- Rickettsia felis (Rickettsia azadi)
Length = 236
Score = 35.5 bits (78), Expect = 1.8
Identities = 20/83 (24%), Positives = 44/83 (53%)
Frame = +1
Query: 268 DRITAGDGVKAHDLEGKAAISNQTNAKVFEILKSAGIKTAFVKIASETAFLSKKCEMIPI 447
D +T G + ++ GK ++N ++ + + L+ GI+ F++ + L + E+ P+
Sbjct: 28 DNVTLESG-EIIEISGKGVLNNNISSFLMDKLEMNGIENHFIEKINMREQLIQYVEVFPV 86
Query: 448 EWVTRRLATGSFLKRNPGVPEGF 516
+ + +A G F+K G+ EG+
Sbjct: 87 QVIISSVACGRFVKEF-GMDEGY 108
>UniRef50_A7DSW8 Cluster:
Phosphoribosylaminoimidazolesuccinocarboxamide synthase;
n=1; Candidatus Nitrosopumilus maritimus SCM1|Rep:
Phosphoribosylaminoimidazolesuccinocarboxamide synthase
- Candidatus Nitrosopumilus maritimus SCM1
Length = 274
Score = 34.3 bits (75), Expect = 4.2
Identities = 28/83 (33%), Positives = 37/83 (44%), Gaps = 7/83 (8%)
Frame = +1
Query: 286 DGVKAHDLEGKAAI--SNQTNAKVFEI-LKSAGIKTAFVKIASETAFLSKKCEMIPIEWV 456
D V A+D++ K I + K E + F+K SE L KK +M+PIE V
Sbjct: 26 DRVSAYDVKFKQDIPRKGEVLCKFAEFWFNELDVPNHFIKRESENEILVKKMKMLPIECV 85
Query: 457 TRRLATGSFLKR----NPGVPEG 513
R GS + R VPEG
Sbjct: 86 VRGYFYGSLVSRWKKGEVQVPEG 108
>UniRef50_Q8QTC7 Cluster: WSSV346; n=2; Shrimp white spot syndrome
virus|Rep: WSSV346 - White spot syndrome virus (WSSV)
Length = 92
Score = 33.5 bits (73), Expect = 7.3
Identities = 22/60 (36%), Positives = 32/60 (53%)
Frame = -2
Query: 521 TLKPSGTPGFLFKNEPVARRRVTHSMGIISHFLDKNAVSEAILTKAVLIPADFKISNTFA 342
TL S F+FKN PV R+T +G+ +L+++ EA T+ ADFK S T +
Sbjct: 27 TLMKSSRSLFIFKNRPVGTGRLTTLIGVSDEYLEEDDGEEA--TEV----ADFKFSATLS 80
>UniRef50_A4SAQ9 Cluster:
Phosphoribosylaminoimidazole-succinocarboxamide
synthase; n=1; Ostreococcus lucimarinus CCE9901|Rep:
Phosphoribosylaminoimidazole-succinocarboxamide synthase
- Ostreococcus lucimarinus CCE9901
Length = 367
Score = 33.5 bits (73), Expect = 7.3
Identities = 23/76 (30%), Positives = 38/76 (50%)
Frame = +1
Query: 253 LLLNKDRITAGDGVKAHDLEGKAAISNQTNAKVFEILKSAGIKTAFVKIASETAFLSKKC 432
+ + DR +A D A+ + K A+ NQT+ F+ + + A V + ++C
Sbjct: 87 IAVTTDRQSAFDRHLAY-IPFKGAVLNQTSQWWFKQTEHI-VPNAVVATPDPNVTVMRRC 144
Query: 433 EMIPIEWVTRRLATGS 480
E+ PIE+V R TGS
Sbjct: 145 EVFPIEFVVRGYLTGS 160
Database: uniref50
Posted date: Oct 5, 2007 11:19 AM
Number of letters in database: 575,637,011
Number of sequences in database: 1,657,284
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 831,153,914
Number of Sequences: 1657284
Number of extensions: 16661694
Number of successful extensions: 37456
Number of sequences better than 10.0: 45
Number of HSP's better than 10.0 without gapping: 36234
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 37447
length of database: 575,637,011
effective HSP length: 100
effective length of database: 409,908,611
effective search space used: 79522270534
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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