Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= MFBP07_F_K22
(869 letters)
Database: uniref50
1,657,284 sequences; 575,637,011 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
UniRef50_UPI0000D56743 Cluster: PREDICTED: similar to 3-hydroxyi... 74 5e-12
UniRef50_A7UBP6 Cluster: Putative 3-hydroxyisobutyrate dehydroge... 73 7e-12
UniRef50_Q7NWA9 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=7... 68 4e-10
UniRef50_Q1AVA4 Cluster: 2-hydroxy-3-oxopropionate reductase; n=... 67 6e-10
UniRef50_O34948 Cluster: Uncharacterized oxidoreductase ykwC; n=... 66 1e-09
UniRef50_UPI00015B4162 Cluster: PREDICTED: similar to MGC108315 ... 65 3e-09
UniRef50_A6NVP0 Cluster: Putative uncharacterized protein; n=1; ... 64 4e-09
UniRef50_Q399N0 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=7... 64 6e-09
UniRef50_A5V0D4 Cluster: 6-phosphogluconate dehydrogenase, NAD-b... 63 1e-08
UniRef50_P28811 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=7... 62 1e-08
UniRef50_P31937 Cluster: 3-hydroxyisobutyrate dehydrogenase, mit... 62 1e-08
UniRef50_A7JGH8 Cluster: Predicted protein; n=1; Francisella tul... 62 2e-08
UniRef50_Q0SBQ9 Cluster: 2-hydroxy-3-oxopropionate reductase; n=... 62 2e-08
UniRef50_Q9K9L1 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=2... 61 3e-08
UniRef50_Q54CX6 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=3... 61 3e-08
UniRef50_Q0K0E2 Cluster: 3-Hydroxyisobutyrate dehydrogenase; n=1... 61 4e-08
UniRef50_A0JUJ6 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=2... 61 4e-08
UniRef50_Q4FMJ3 Cluster: 6-phosphogluconate dehydrogenase; n=2; ... 60 5e-08
UniRef50_Q1QWU9 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=1... 60 9e-08
UniRef50_Q01ZG6 Cluster: 2-hydroxy-3-oxopropionate reductase; n=... 60 9e-08
UniRef50_A3I4V2 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=1... 59 1e-07
UniRef50_Q8ES28 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=1... 58 2e-07
UniRef50_Q83D20 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=9... 58 2e-07
UniRef50_Q0QLF5 Cluster: 2-hydroxymethyl glutarate dehydrogenase... 58 2e-07
UniRef50_Q2JEV5 Cluster: 6-phosphogluconate dehydrogenase, NAD-b... 58 3e-07
UniRef50_Q58PL4 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=1... 57 7e-07
UniRef50_A3RRS1 Cluster: 2-hydroxy-3-oxopropionate reductase; n=... 57 7e-07
UniRef50_A0QSJ0 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=3... 57 7e-07
UniRef50_Q03UI4 Cluster: 3-hydroxyisobutyrate dehydrogenase rela... 56 9e-07
UniRef50_A6P2M7 Cluster: Putative uncharacterized protein; n=2; ... 56 9e-07
UniRef50_A1SIN3 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=1... 56 9e-07
UniRef50_A1QPH6 Cluster: 3-hydroxyisobutyrate dehydrogenase mmsB... 56 1e-06
UniRef50_Q22B54 Cluster: 3-hydroxyisobutyrate dehydrogenase fami... 56 1e-06
UniRef50_P63936 Cluster: Probable 3-hydroxyisobutyrate dehydroge... 56 1e-06
UniRef50_Q92D17 Cluster: Lin1004 protein; n=10; Bacilli|Rep: Lin... 56 2e-06
UniRef50_Q5WBB8 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=1... 55 2e-06
UniRef50_A4IN46 Cluster: 3-hydroxyisobutyrate dehydrogenase-like... 55 2e-06
UniRef50_Q1QWQ5 Cluster: 6-phosphogluconate dehydrogenase, NAD-b... 55 3e-06
UniRef50_A5VEA3 Cluster: 2-hydroxy-3-oxopropionate reductase; n=... 55 3e-06
UniRef50_A0UF54 Cluster: 6-phosphogluconate dehydrogenase, NAD-b... 55 3e-06
UniRef50_A0K0Z6 Cluster: 6-phosphogluconate dehydrogenase, NAD-b... 55 3e-06
UniRef50_Q5L168 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=1... 54 4e-06
UniRef50_Q12CU4 Cluster: 2-hydroxy-3-oxopropionate reductase; n=... 54 4e-06
UniRef50_A0LMG6 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=9... 54 4e-06
UniRef50_Q55702 Cluster: Uncharacterized oxidoreductase slr0229;... 54 4e-06
UniRef50_A5GPC0 Cluster: Hydroxyacid dehydrogenase/reductase fam... 54 5e-06
UniRef50_A3VLN6 Cluster: Oxidoreductase; n=1; Rhodobacterales ba... 54 5e-06
UniRef50_Q67QX0 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=1... 54 6e-06
UniRef50_Q97XZ7 Cluster: Oxidoreductase; n=6; Thermoprotei|Rep: ... 54 6e-06
UniRef50_Q9SUC0 Cluster: Probable 3-hydroxyisobutyrate dehydroge... 54 6e-06
UniRef50_A6GTB5 Cluster: 6-phosphogluconate dehydrogenase, NAD-b... 53 8e-06
UniRef50_A2U9T6 Cluster: 6-phosphogluconate dehydrogenase, NAD-b... 53 8e-06
UniRef50_Q9A8J9 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=2... 52 1e-05
UniRef50_Q183P5 Cluster: 2-hydroxy-3-oxopropionate reductase; n=... 52 1e-05
UniRef50_A0N0V2 Cluster: BtdhL; n=1; Azoarcus anaerobius|Rep: Bt... 52 1e-05
UniRef50_Q930C6 Cluster: Probable; n=8; Alphaproteobacteria|Rep:... 52 2e-05
UniRef50_Q6UCZ9 Cluster: Predicted oxidoreductase; n=2; environm... 52 2e-05
UniRef50_Q1V2R0 Cluster: MmsB-like protein; n=2; Candidatus Pela... 52 2e-05
UniRef50_Q0S5S3 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=1... 52 2e-05
UniRef50_Q0RCX7 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=1... 52 2e-05
UniRef50_A6SUL3 Cluster: 2-hydroxy-3-oxopropionate reductase; n=... 52 3e-05
UniRef50_A6LT11 Cluster: 6-phosphogluconate dehydrogenase, NAD-b... 52 3e-05
UniRef50_Q4KH51 Cluster: 3-hydroxyisobutyrate dehydrogenase fami... 51 3e-05
UniRef50_A3EW86 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=1... 51 3e-05
UniRef50_Q11FC5 Cluster: 6-phosphogluconate dehydrogenase, NAD-b... 51 4e-05
UniRef50_A6G049 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=1... 51 4e-05
UniRef50_A1B741 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=3... 51 4e-05
UniRef50_A0LTQ8 Cluster: 6-phosphogluconate dehydrogenase, NAD-b... 51 4e-05
UniRef50_A0GVR3 Cluster: 6-phosphogluconate dehydrogenase, NAD-b... 50 6e-05
UniRef50_Q9V8M5-2 Cluster: Isoform C of Q9V8M5 ; n=1; Drosophila... 50 1e-04
UniRef50_A0C2T7 Cluster: Chromosome undetermined scaffold_145, w... 50 1e-04
UniRef50_Q9V8M5 Cluster: Probable 3-hydroxyisobutyrate dehydroge... 50 1e-04
UniRef50_Q47AR2 Cluster: NADP oxidoreductase, coenzyme F420-depe... 49 1e-04
UniRef50_Q1B326 Cluster: 6-phosphogluconate dehydrogenase, NAD-b... 49 1e-04
UniRef50_Q9L7S0 Cluster: Uncharacterized oxidoreductase yihU; n=... 49 1e-04
UniRef50_Q5FQ06 Cluster: Putative oxidoreductase; n=1; Gluconoba... 49 2e-04
UniRef50_Q4ZQL5 Cluster: 3-hydroxyisobutyrate dehydrogenase prec... 49 2e-04
UniRef50_A1UP64 Cluster: 6-phosphogluconate dehydrogenase, NAD-b... 49 2e-04
UniRef50_Q8KL12 Cluster: Probable 6-phosphogluconate dehydrogena... 48 2e-04
UniRef50_Q606G9 Cluster: Oxidoreductase, Gfo/Idh/MocA family; n=... 48 2e-04
UniRef50_A5USN9 Cluster: 6-phosphogluconate dehydrogenase, NAD-b... 48 2e-04
UniRef50_Q3DYV4 Cluster: NADP oxidoreductase, coenzyme F420-depe... 48 3e-04
UniRef50_Q0LNZ7 Cluster: 3-hydroxyisobutyrate dehydrogenase prec... 48 3e-04
UniRef50_Q01QM2 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=1... 48 3e-04
UniRef50_A2SP40 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=1... 48 3e-04
UniRef50_P77161 Cluster: 2-hydroxy-3-oxopropionate reductase; n=... 48 3e-04
UniRef50_A5P0V0 Cluster: 6-phosphogluconate dehydrogenase, NAD-b... 48 4e-04
UniRef50_A1R2J4 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=1... 47 5e-04
UniRef50_A0G5F9 Cluster: 6-phosphogluconate dehydrogenase, NAD-b... 47 5e-04
UniRef50_P0ABQ3 Cluster: 2-hydroxy-3-oxopropionate reductase; n=... 47 5e-04
UniRef50_Q89R44 Cluster: Oxidoreductase; n=23; Bacteria|Rep: Oxi... 47 7e-04
UniRef50_A6EH53 Cluster: Putative uncharacterized protein; n=1; ... 47 7e-04
UniRef50_A3WAC4 Cluster: Dehydrogenase; n=4; Bacteria|Rep: Dehyd... 47 7e-04
UniRef50_A0NRG5 Cluster: 6-phosphogluconate dehydrogenase, NAD-b... 47 7e-04
UniRef50_A3H9B3 Cluster: 6-phosphogluconate dehydrogenase, NAD-b... 47 7e-04
UniRef50_Q7WG50 Cluster: Probable oxidoreductase; n=1; Bordetell... 46 0.001
UniRef50_A6SW62 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=1... 46 0.001
UniRef50_A4SWE8 Cluster: 2-hydroxy-3-oxopropionate reductase pre... 46 0.001
UniRef50_A3X9R7 Cluster: 3-hydroxyisobutyrate dehydrogenase fami... 46 0.001
UniRef50_A0LDJ3 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=1... 46 0.001
UniRef50_A0G5G5 Cluster: 6-phosphogluconate dehydrogenase, NAD-b... 46 0.001
UniRef50_Q7VYY0 Cluster: Putative oxidoreductase; n=4; Bordetell... 46 0.001
UniRef50_A3SJ77 Cluster: Probable oxidoreductase; n=1; Roseovari... 46 0.001
UniRef50_Q1N6I0 Cluster: Putative oxidoreductase protein; n=1; O... 46 0.002
UniRef50_Q41DK0 Cluster: 6-phosphogluconate dehydrogenase, NAD-b... 45 0.002
UniRef50_Q1IQE6 Cluster: 2-hydroxy-3-oxopropionate reductase pre... 45 0.002
UniRef50_A7H7Z5 Cluster: 6-phosphogluconate dehydrogenase NAD-bi... 45 0.002
UniRef50_A0QUD5 Cluster: 3-hydroxyisobutyrate dehydrogenase fami... 45 0.002
UniRef50_Q89UN2 Cluster: Bll1384 protein; n=9; Bacteria|Rep: Bll... 45 0.003
UniRef50_Q73P00 Cluster: 3-hydroxyacid dehydrogenase family prot... 45 0.003
UniRef50_A0JXR2 Cluster: 2-hydroxy-3-oxopropionate reductase; n=... 45 0.003
UniRef50_Q94B07 Cluster: Gamma hydroxybutyrate dehydrogenase; n=... 45 0.003
UniRef50_Q1GJB9 Cluster: 6-phosphogluconate dehydrogenase NAD-bi... 44 0.004
UniRef50_Q84VC8 Cluster: Gamma hydroxybutyrate dehydrogenase-lik... 44 0.004
UniRef50_Q1YHQ4 Cluster: Putative 2-hydroxy-3-oxopropionate redu... 44 0.005
UniRef50_Q4Q7T9 Cluster: 2-hydroxy-3-oxopropionate reductase, pu... 44 0.005
UniRef50_Q8TUC1 Cluster: Predicted protein; n=4; Methanosarcinac... 44 0.005
UniRef50_Q89HA0 Cluster: Oxidoreductase; n=1; Bradyrhizobium jap... 44 0.007
UniRef50_Q18X68 Cluster: 6-phosphogluconate dehydrogenase, NAD-b... 44 0.007
UniRef50_A3H5R1 Cluster: 6-phosphogluconate dehydrogenase, NAD-b... 44 0.007
UniRef50_O33730 Cluster: Uncharacterized oxidoreductase Sfri_150... 44 0.007
UniRef50_Q84H84 Cluster: Putative oxidoreductase; n=1; Arthrobac... 43 0.012
UniRef50_Q3W9W7 Cluster: 6-phosphogluconate dehydrogenase, NAD b... 43 0.012
UniRef50_Q13LQ9 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=1... 43 0.012
UniRef50_A7PEG7 Cluster: Chromosome chr11 scaffold_13, whole gen... 43 0.012
UniRef50_Q6C351 Cluster: Yarrowia lipolytica chromosome F of str... 43 0.012
UniRef50_A0GPK7 Cluster: 6-phosphogluconate dehydrogenase, NAD-b... 42 0.015
UniRef50_Q4Q9Z1 Cluster: Dehydrogenase-like protein; n=6; Trypan... 42 0.015
UniRef50_Q55JR1 Cluster: Putative uncharacterized protein; n=2; ... 42 0.015
UniRef50_Q98I20 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=2... 42 0.020
UniRef50_Q2JEN4 Cluster: 6-phosphogluconate dehydrogenase, NAD-b... 42 0.020
UniRef50_Q9LNP0 Cluster: F1L3.35; n=8; Magnoliophyta|Rep: F1L3.3... 42 0.020
UniRef50_Q49A26 Cluster: Cytokine-like nuclear factor n-pac; n=4... 42 0.020
UniRef50_Q830A7 Cluster: 2-hydroxy-3-oxopropionate reductase; n=... 42 0.027
UniRef50_Q7WNK6 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=1... 42 0.027
UniRef50_Q39FA8 Cluster: 2-hydroxy-3-oxopropionate reductase; n=... 42 0.027
UniRef50_Q392H4 Cluster: 6-phosphogluconate dehydrogenase, NAD-b... 42 0.027
UniRef50_Q12H32 Cluster: 6-phosphogluconate dehydrogenase, NAD-b... 42 0.027
UniRef50_Q0FFH2 Cluster: Putative 2-hydroxyacid dehydrogenase; n... 42 0.027
UniRef50_A3JU55 Cluster: Predicted dehydrogenase, with NAD(P)-bi... 42 0.027
UniRef50_Q8TT25 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=2... 42 0.027
UniRef50_Q6KZX0 Cluster: 2-hydroxy-3-oxopropionate reductase; n=... 42 0.027
UniRef50_A7IE35 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=2... 41 0.036
UniRef50_A3K497 Cluster: Probable 6-phosphogluconate dehydrogena... 41 0.047
UniRef50_Q8VYC5 Cluster: Fructose-bisphosphate aldolase; n=12; c... 41 0.047
UniRef50_A1CAY2 Cluster: Oxidoreductase, acting on the CH-OH gro... 41 0.047
UniRef50_O34969 Cluster: Uncharacterized oxidoreductase yfjR; n=... 41 0.047
UniRef50_P71825 Cluster: Uncharacterized oxidoreductase Rv0770/M... 41 0.047
UniRef50_Q82ZC2 Cluster: 6-phosphogluconate dehydrogenase family... 40 0.062
UniRef50_A5VBF0 Cluster: 2-hydroxy-3-oxopropionate reductase pre... 40 0.062
UniRef50_A0FZ96 Cluster: 6-phosphogluconate dehydrogenase, NAD-b... 40 0.062
UniRef50_Q4WV01 Cluster: Oxidoreductase, acting on the CH-OH gro... 40 0.062
UniRef50_Q0UVR9 Cluster: Putative uncharacterized protein; n=1; ... 40 0.062
UniRef50_Q8UBW3 Cluster: Oxidoredutase; n=1; Agrobacterium tumef... 40 0.082
UniRef50_Q89RT2 Cluster: Bll2680 protein; n=1; Bradyrhizobium ja... 40 0.082
UniRef50_Q89M84 Cluster: Blr4309 protein; n=6; Bradyrhizobiaceae... 40 0.082
UniRef50_Q5LQR0 Cluster: 6-phosphogluconate dehydrogenase domain... 40 0.082
UniRef50_Q39MY1 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=2... 40 0.082
UniRef50_Q3W3N3 Cluster: Putative uncharacterized protein; n=1; ... 40 0.082
UniRef50_Q1GF31 Cluster: 6-phosphogluconate dehydrogenase NAD-bi... 40 0.082
UniRef50_A6R0U9 Cluster: Predicted protein; n=1; Ajellomyces cap... 40 0.082
UniRef50_Q4PCH4 Cluster: Putative uncharacterized protein; n=1; ... 40 0.11
UniRef50_Q1EPJ1 Cluster: 6-phosphogluconate dehydrogenase NAD-bi... 39 0.14
UniRef50_Q2UHA9 Cluster: Predicted dehydrogenase; n=16; Pezizomy... 39 0.14
UniRef50_Q3W9L4 Cluster: Putative uncharacterized protein; n=1; ... 39 0.19
UniRef50_A4ENK2 Cluster: 3-demethylubiquinone-9 3-methyltransfer... 39 0.19
UniRef50_Q7WCG3 Cluster: Putative uncharacterized protein; n=2; ... 38 0.25
UniRef50_Q2BFK1 Cluster: Oxidoreductase; n=1; Bacillus sp. NRRL ... 38 0.25
UniRef50_Q220G7 Cluster: 6-phosphogluconate dehydrogenase, NAD-b... 38 0.25
UniRef50_A3LTC4 Cluster: 3-hydroxyisobutyrate dehydrogenase-like... 38 0.25
UniRef50_UPI0001597301 Cluster: YfjR; n=1; Bacillus amyloliquefa... 38 0.33
UniRef50_Q74D68 Cluster: 3-hydroxyisobutyrate dehydrogenase fami... 38 0.33
UniRef50_Q0F1Y7 Cluster: 6-phosphogluconate dehydrogenase, NAD-b... 38 0.33
UniRef50_A2C1U6 Cluster: 3-hydroxyisobutyrate dehydrogenase and ... 38 0.33
UniRef50_Q0C8I2 Cluster: Predicted protein; n=3; Pezizomycotina|... 38 0.33
UniRef50_Q9YFQ6 Cluster: L-lysine 6-dehydrogenase; n=1; Aeropyru... 38 0.33
UniRef50_UPI0000E49FD0 Cluster: PREDICTED: similar to gamma hydr... 38 0.44
UniRef50_Q39KK8 Cluster: 6-phosphogluconate dehydrogenase, NAD-b... 38 0.44
UniRef50_Q121N3 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=1... 38 0.44
UniRef50_A3PSD9 Cluster: 6-phosphogluconate dehydrogenase, decar... 38 0.44
UniRef50_A1GFG2 Cluster: 6-phosphogluconate dehydrogenase, NAD-b... 38 0.44
UniRef50_A6RMW8 Cluster: Putative uncharacterized protein; n=2; ... 38 0.44
UniRef50_A5FTT0 Cluster: 6-phosphogluconate dehydrogenase, NAD-b... 37 0.58
UniRef50_A1ZWM5 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=1... 37 0.58
UniRef50_A1UJF2 Cluster: 6-phosphogluconate dehydrogenase, NAD-b... 37 0.58
UniRef50_A0R1N4 Cluster: 6-phosphogluconate dehydrogenase, NAD-b... 37 0.58
UniRef50_Q9LM23 Cluster: Fructose-bisphosphate aldolase; n=2; Ar... 37 0.58
UniRef50_Q656T5 Cluster: Oxidoreductase-like; n=3; Oryza sativa|... 37 0.77
UniRef50_Q988C8 Cluster: 3-hydroxybutyryl-coA dehydrogenase; n=1... 36 1.0
UniRef50_Q3J9H5 Cluster: 6-phosphogluconate dehydrogenase, decar... 36 1.0
UniRef50_Q1YFU0 Cluster: Posibble methylase involved in ubiquino... 36 1.0
UniRef50_A6F020 Cluster: Putative uncharacterized protein; n=1; ... 36 1.0
UniRef50_A1WM48 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=1... 36 1.0
UniRef50_A0JRK4 Cluster: 6-phosphogluconate dehydrogenase, NAD-b... 36 1.0
UniRef50_Q21AH6 Cluster: 6-phosphogluconate dehydrogenase, NAD-b... 36 1.3
UniRef50_Q1INE9 Cluster: 6-phosphogluconate dehydrogenase, NAD-b... 36 1.3
UniRef50_Q0KC92 Cluster: 3-Hydroxyisobutyrate dehydrogenase; n=1... 36 1.3
UniRef50_A4ES45 Cluster: Methyltransferase type 11; n=1; Roseoba... 36 1.3
UniRef50_A4ARS6 Cluster: 6-phosphogluconate dehydrogenase, NAD-b... 36 1.3
UniRef50_Q0URA2 Cluster: Putative uncharacterized protein; n=1; ... 36 1.3
UniRef50_Q944B6 Cluster: Arogenate dehydrogenase 1, chloroplast ... 36 1.3
UniRef50_Q8PK98 Cluster: 3-hydroxyisobutirate dehydrogenase; n=3... 36 1.8
UniRef50_Q5PAV2 Cluster: 3-demethylubiquinone-9 3-methyltransfer... 36 1.8
UniRef50_Q0RMX6 Cluster: Putative reductase; n=1; Frankia alni A... 36 1.8
UniRef50_A6W129 Cluster: 6-phosphogluconate dehydrogenase, decar... 36 1.8
UniRef50_Q019Z7 Cluster: Oxidoreductase-like; n=1; Ostreococcus ... 36 1.8
UniRef50_A7SFT5 Cluster: Predicted protein; n=1; Nematostella ve... 36 1.8
UniRef50_Q2LGT9 Cluster: 6-phosphogluconate dehydrogenase; n=6; ... 36 1.8
UniRef50_Q1N6E5 Cluster: Erythronate-4-phosphate dehydrogenase; ... 35 2.3
UniRef50_A6VZU5 Cluster: D-isomer specific 2-hydroxyacid dehydro... 35 2.3
UniRef50_A6VLT0 Cluster: 2-hydroxy-3-oxopropionate reductase; n=... 35 2.3
UniRef50_A0RU56 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=1... 35 2.3
UniRef50_UPI00015B50D2 Cluster: PREDICTED: similar to conserved ... 35 3.1
UniRef50_UPI0000E46E06 Cluster: PREDICTED: similar to MGC107852 ... 35 3.1
UniRef50_Q9RU02 Cluster: 6-phosphogluconate dehydrogenase; n=24;... 35 3.1
UniRef50_Q9I1R8 Cluster: Probable dehydrogenase; n=7; Pseudomona... 35 3.1
UniRef50_Q2S7E0 Cluster: Phosphoglycerate dehydrogenase and rela... 35 3.1
UniRef50_Q20XN2 Cluster: 6-phosphogluconate dehydrogenase, NAD-b... 35 3.1
UniRef50_A5CN67 Cluster: Putative beta-hydroxyacid dehydrogenase... 35 3.1
UniRef50_A4XCN7 Cluster: Methyltransferase type 11; n=2; Salinis... 35 3.1
UniRef50_A3Y0Y8 Cluster: Putative tartronate semialdehyde reduct... 35 3.1
UniRef50_A3U721 Cluster: Putative uncharacterized protein; n=1; ... 35 3.1
UniRef50_Q4WXG9 Cluster: 3-hydroxyisobutyrate dehydrogenase, put... 35 3.1
UniRef50_A7DSF1 Cluster: 2-hydroxy-3-oxopropionate reductase; n=... 35 3.1
UniRef50_UPI0000E221EA Cluster: PREDICTED: similar to NMDAR1 sub... 34 4.1
UniRef50_UPI000050FDFD Cluster: COG0569: K+ transport systems, N... 34 4.1
UniRef50_Q7WCB1 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=4... 34 4.1
UniRef50_A4ECY9 Cluster: Putative uncharacterized protein; n=1; ... 34 4.1
UniRef50_A3WMG5 Cluster: Probable 3-hydroxyisobutyrate dehydroge... 34 4.1
UniRef50_A1SM51 Cluster: D-3-phosphoglycerate dehydrogenase; n=1... 34 4.1
UniRef50_A0GI22 Cluster: 6-phosphogluconate dehydrogenase, NAD-b... 34 4.1
UniRef50_A0AWL7 Cluster: 6-phosphogluconate dehydrogenase, NAD-b... 34 4.1
UniRef50_Q7NR40 Cluster: Probable 3-hydroxyisobutyrate dehydroge... 34 5.4
UniRef50_Q5GUM4 Cluster: Dehydrogenase; n=5; Gammaproteobacteria... 34 5.4
UniRef50_Q0SAG5 Cluster: Phosphogluconate dehydrogenase; n=23; A... 34 5.4
UniRef50_Q3DWX0 Cluster: 6-phosphogluconate dehydrogenase, NAD-b... 34 5.4
UniRef50_Q21ZT0 Cluster: 6-phosphogluconate dehydrogenase, NAD-b... 34 5.4
UniRef50_Q033P2 Cluster: 3-hydroxyisobutyrate dehydrogenase rela... 34 5.4
UniRef50_A6G079 Cluster: Leucine dehydrogenase; n=1; Plesiocysti... 34 5.4
UniRef50_A4SGI3 Cluster: NAD-dependent epimerase/dehydratase; n=... 34 5.4
UniRef50_A0Y665 Cluster: 6-phosphogluconate dehydrogenase; n=3; ... 34 5.4
UniRef50_Q8U2W2 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=1... 34 5.4
UniRef50_A3H6C3 Cluster: 6-phosphogluconate dehydrogenase, NAD-b... 34 5.4
UniRef50_Q8EW87 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=1... 33 7.1
UniRef50_Q6N3Q8 Cluster: 6-phosphogluconate dehydrogenase; n=57;... 33 7.1
UniRef50_Q5LNV6 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=2... 33 7.1
UniRef50_Q6RXW5 Cluster: Succinic semialdehyde dehydrogenase; n=... 33 7.1
UniRef50_Q0S6F7 Cluster: 3-demethylubiquinone-9 3-O-methyltransf... 33 7.1
UniRef50_A5P600 Cluster: 6-phosphogluconate dehydrogenase, NAD-b... 33 7.1
UniRef50_A0Z3U5 Cluster: Putative uncharacterized protein; n=1; ... 33 7.1
UniRef50_A7QQA4 Cluster: Chromosome undetermined scaffold_141, w... 33 7.1
UniRef50_A7RG59 Cluster: Predicted protein; n=1; Nematostella ve... 33 7.1
UniRef50_Q55W03 Cluster: Putative uncharacterized protein; n=2; ... 33 7.1
UniRef50_Q0VQC3 Cluster: Erythronate-4-phosphate dehydrogenase; ... 33 7.1
UniRef50_Q88ZU6 Cluster: Phosphoglycerate dehydrogenase; n=2; La... 33 9.4
UniRef50_Q6F842 Cluster: Putative 3-hydroxyisobutyrate dehydroge... 33 9.4
UniRef50_Q6F272 Cluster: 1-pyrroline-5-carboxylate reductase; n=... 33 9.4
UniRef50_O67636 Cluster: Prephenate dehydrogenase; n=1; Aquifex ... 33 9.4
UniRef50_Q9RQV3 Cluster: Putative prephenate dehydrogenase TyrC;... 33 9.4
UniRef50_Q2CHC8 Cluster: Oxidoreductase; n=1; Oceanicola granulo... 33 9.4
UniRef50_Q2BJD5 Cluster: Probable UDP-glucose/GDP-mannose dehydr... 33 9.4
UniRef50_Q120Q9 Cluster: 6-phosphogluconate dehydrogenase, NAD-b... 33 9.4
UniRef50_Q031D4 Cluster: Phosphoglycerate dehydrogenase; n=20; S... 33 9.4
UniRef50_A6TCR4 Cluster: 2-ketoacid reductase; n=1; Klebsiella p... 33 9.4
UniRef50_A6NX21 Cluster: Putative uncharacterized protein; n=1; ... 33 9.4
UniRef50_A3ET09 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=3... 33 9.4
UniRef50_A1SQ87 Cluster: 6-phosphogluconate dehydrogenase, NAD-b... 33 9.4
>UniRef50_UPI0000D56743 Cluster: PREDICTED: similar to
3-hydroxyisobutyrate dehydrogenase; n=1; Tribolium
castaneum|Rep: PREDICTED: similar to
3-hydroxyisobutyrate dehydrogenase - Tribolium castaneum
Length = 315
Score = 73.7 bits (173), Expect = 5e-12
Identities = 39/93 (41%), Positives = 49/93 (52%)
Frame = +2
Query: 407 GKDGVVAHAKKGSLLIDSSTIDXNVPQQIFPIALEKGLGFTDAPVSGRVMGCSKRYLAFM 586
G +G++ HA KGSLLID STI V Q++ G F DAPVSG V G L FM
Sbjct: 97 GTNGILKHASKGSLLIDCSTIQPQVAQEVSKATYSAGFKFLDAPVSGGVTGAEAGTLTFM 156
Query: 587 AGXRKKNFERSLPLLQVMGANSXTADRSGSXXV 685
G K+ + P+L MGAN SG+ +
Sbjct: 157 VGGDKQVLNSADPILMKMGANVLHCGDSGAGQI 189
Score = 46.4 bits (105), Expect = 0.001
Identities = 28/74 (37%), Positives = 39/74 (52%)
Frame = +1
Query: 187 VAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGVTPANSIXXXXXXXXXXXS 366
+AF+G+GNMG MA NLVKKG TVR +D + NA + G N+ +
Sbjct: 26 LAFIGIGNMGSRMANNLVKKGETVRVFDLT--PANAKSVPGAQVCNNQEEAVKDASVIIT 83
Query: 367 ILTSNKVVLDVYLG 408
+L + +V D LG
Sbjct: 84 MLPNGDIVKDTVLG 97
Score = 36.3 bits (80), Expect = 1.0
Identities = 23/57 (40%), Positives = 32/57 (56%), Gaps = 1/57 (1%)
Frame = +3
Query: 693 LXXXMLMGLTGMATAECMNMGIKMGLXPKGLVG-TS*KTHRAPSLVDRRXYCPXPGL 860
L +++ +T + T E MN+GIKMGL PK L + T R+ S + Y P PGL
Sbjct: 192 LCNNLILAITMIGTCEGMNLGIKMGLDPKTLASIINVSTGRSWS---SQTYNPVPGL 245
>UniRef50_A7UBP6 Cluster: Putative 3-hydroxyisobutyrate
dehydrogenase; n=1; Paracoccus methylutens|Rep: Putative
3-hydroxyisobutyrate dehydrogenase - Paracoccus
methylutens
Length = 302
Score = 73.3 bits (172), Expect = 7e-12
Identities = 38/89 (42%), Positives = 50/89 (56%)
Frame = +2
Query: 407 GKDGVVAHAKKGSLLIDSSTIDXNVPQQIFPIALEKGLGFTDAPVSGRVMGCSKRYLAFM 586
G DGV+A KGS+ IDSSTID +++ E+G+ DAPVSG VMG L FM
Sbjct: 77 GDDGVLAKMAKGSMAIDSSTIDTADARRLHAAGRERGIAVLDAPVSGGVMGAEAGTLTFM 136
Query: 587 AGXRKKNFERSLPLLQVMGANSXTADRSG 673
G ++ ER+ P+L+ MG A G
Sbjct: 137 VGGSAEDLERARPVLEAMGRRIFHAGEPG 165
Score = 51.2 bits (117), Expect = 3e-05
Identities = 27/74 (36%), Positives = 40/74 (54%)
Frame = +1
Query: 187 VAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGVTPANSIXXXXXXXXXXXS 366
V FLGLG MG MA NL G V YDPS++ AAK G+ A+ + +
Sbjct: 4 VGFLGLGRMGFPMARNLATAGHDVHVYDPSEEVGRKAAKAGLKTASRVDVAVEGADFVIT 63
Query: 367 ILTSNKVVLDVYLG 408
++ + + VL+++LG
Sbjct: 64 MVPTGRHVLEIFLG 77
>UniRef50_Q7NWA9 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=7;
Proteobacteria|Rep: 3-hydroxyisobutyrate dehydrogenase -
Chromobacterium violaceum
Length = 296
Score = 67.7 bits (158), Expect = 4e-10
Identities = 37/101 (36%), Positives = 54/101 (53%)
Frame = +2
Query: 374 PAIKSCSTCTWGKDGVVAHAKKGSLLIDSSTIDXNVPQQIFPIALEKGLGFTDAPVSGRV 553
PA K + G +G+ A KG+L+ID STID +++ A EKGL DAPVSG
Sbjct: 66 PAGKHVAGLYLGDNGLFARLPKGALVIDCSTIDAGTARKVAEGAREKGLSMLDAPVSGGT 125
Query: 554 MGCSKRYLAFMAGXRKKNFERSLPLLQVMGANSXTADRSGS 676
G + L F+ G ++ + P+L+ MG N A +G+
Sbjct: 126 AGAAAGTLTFIVGGAAEDLAHARPVLEAMGKNIFHAGGAGA 166
Score = 62.9 bits (146), Expect = 1e-08
Identities = 34/76 (44%), Positives = 43/76 (56%)
Frame = +1
Query: 181 KNVAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGVTPANSIXXXXXXXXXX 360
+N+AF+GLGNMGG MA NL+ KGF V +D S DAL A G A+S
Sbjct: 2 ENIAFIGLGNMGGPMAVNLLNKGFKVSAFDLSADALAKVAAAGGRAASSAADAAESASVV 61
Query: 361 XSILTSNKVVLDVYLG 408
S+L + K V +YLG
Sbjct: 62 ISMLPAGKHVAGLYLG 77
>UniRef50_Q1AVA4 Cluster: 2-hydroxy-3-oxopropionate reductase; n=6;
Bacteria|Rep: 2-hydroxy-3-oxopropionate reductase -
Rubrobacter xylanophilus (strain DSM 9941 / NBRC 16129)
Length = 309
Score = 66.9 bits (156), Expect = 6e-10
Identities = 36/93 (38%), Positives = 53/93 (56%)
Frame = +2
Query: 407 GKDGVVAHAKKGSLLIDSSTIDXNVPQQIFPIALEKGLGFTDAPVSGRVMGCSKRYLAFM 586
G+ GV+ ++GSLLID STI V +Q+ A E+G DAPVSG +G + L+ M
Sbjct: 91 GEGGVLEGMREGSLLIDMSTISPAVARQLAAKARERGASMLDAPVSGGDVGAREGTLSIM 150
Query: 587 AGXRKKNFERSLPLLQVMGANSXTADRSGSXXV 685
G +++F R+ PL +VMG SG+ +
Sbjct: 151 VGGSEEDFGRARPLFEVMGKTVTHVGPSGAGQI 183
>UniRef50_O34948 Cluster: Uncharacterized oxidoreductase ykwC; n=19;
cellular organisms|Rep: Uncharacterized oxidoreductase
ykwC - Bacillus subtilis
Length = 288
Score = 66.1 bits (154), Expect = 1e-09
Identities = 34/91 (37%), Positives = 52/91 (57%)
Frame = +2
Query: 404 WGKDGVVAHAKKGSLLIDSSTIDXNVPQQIFPIALEKGLGFTDAPVSGRVMGCSKRYLAF 583
+G +G++ +AK+G+ LID +T ++ ++I A EK L DAPVSG +G LA
Sbjct: 77 FGSNGIIENAKEGAYLIDMTTSKPSLAKKIAEAAKEKALFALDAPVSGGDIGAQNGTLAI 136
Query: 584 MAGXRKKNFERSLPLLQVMGANSXTADRSGS 676
M G K+ FE +P+ +MG N +GS
Sbjct: 137 MVGGEKEAFEACMPIFSLMGENIQYQGPAGS 167
>UniRef50_UPI00015B4162 Cluster: PREDICTED: similar to MGC108315
protein; n=1; Nasonia vitripennis|Rep: PREDICTED:
similar to MGC108315 protein - Nasonia vitripennis
Length = 276
Score = 64.9 bits (151), Expect = 3e-09
Identities = 36/100 (36%), Positives = 51/100 (51%)
Frame = +1
Query: 139 LYTAARRAYSSNTDKNVAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGVTP 318
+YT R NV F+GLGNMGGFMA NL+KKG+ + +D +K A++ G
Sbjct: 13 IYTVGR--VGQRDFSNVGFVGLGNMGGFMAKNLLKKGYKLTVFDINKTAIDNVVSAGAKG 70
Query: 319 ANSIXXXXXXXXXXXSILTSNKVVLDVYLGQRWRCGSCEK 438
A S+ ++L N+ VLD Y G+ S +K
Sbjct: 71 AESVAEVSQNSEVIVTMLPMNQHVLDTYTGKDGIISSAKK 110
Score = 46.8 bits (106), Expect = 7e-04
Identities = 24/58 (41%), Positives = 35/58 (60%)
Frame = +2
Query: 407 GKDGVVAHAKKGSLLIDSSTIDXNVPQQIFPIALEKGLGFTDAPVSGRVMGCSKRYLA 580
GKDG+++ AKKG+ L+DSSTID +V Q +F A +K + D + C+ LA
Sbjct: 100 GKDGIISSAKKGTFLVDSSTIDPSVSQTVFK-AAQKAVHCGDTGMGQVAKICNNMLLA 156
>UniRef50_A6NVP0 Cluster: Putative uncharacterized protein; n=1;
Bacteroides capillosus ATCC 29799|Rep: Putative
uncharacterized protein - Bacteroides capillosus ATCC
29799
Length = 306
Score = 64.1 bits (149), Expect = 4e-09
Identities = 31/89 (34%), Positives = 49/89 (55%)
Frame = +2
Query: 407 GKDGVVAHAKKGSLLIDSSTIDXNVPQQIFPIALEKGLGFTDAPVSGRVMGCSKRYLAFM 586
GK+GV + K+G+++ID S++ N + + A EKG+ + DAPVSG V G + L M
Sbjct: 81 GKNGVFENCKEGTVIIDMSSVAPNTTKAMAKKAAEKGIHYIDAPVSGGVSGAAAGTLTIM 140
Query: 587 AGXRKKNFERSLPLLQVMGANSXTADRSG 673
G + F + P+ V+G N +G
Sbjct: 141 VGADDETFNKVKPIFDVLGKNIYHVGEAG 169
>UniRef50_Q399N0 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=72;
cellular organisms|Rep: 3-hydroxyisobutyrate
dehydrogenase - Burkholderia sp. (strain 383)
(Burkholderia cepacia (strain ATCC 17760/ NCIB 9086 /
R18194))
Length = 299
Score = 63.7 bits (148), Expect = 6e-09
Identities = 39/104 (37%), Positives = 50/104 (48%)
Frame = +2
Query: 374 PAIKSCSTCTWGKDGVVAHAKKGSLLIDSSTIDXNVPQQIFPIALEKGLGFTDAPVSGRV 553
PA + G++GV+A G+ +IDSSTID Q + E G F DAPVSG
Sbjct: 65 PAAPHVRSVLSGENGVLAGLGAGATVIDSSTIDPASAQAFGALVREHGGAFVDAPVSGGT 124
Query: 554 MGCSKRYLAFMAGXRKKNFERSLPLLQVMGANSXTADRSGSXXV 685
G + L FM G +FER P+L MG N +G V
Sbjct: 125 GGAAAGTLTFMVGGSDADFERVKPVLAGMGKNIVHCGATGMGQV 168
Score = 43.2 bits (97), Expect = 0.009
Identities = 22/47 (46%), Positives = 27/47 (57%)
Frame = +1
Query: 187 VAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGVTPANS 327
+ F+GLG+MG MA NL+K G V +D S DAL A G A S
Sbjct: 3 IGFIGLGHMGAPMALNLLKAGHEVHAFDLSADALRALQDAGAQVAAS 49
>UniRef50_A5V0D4 Cluster: 6-phosphogluconate dehydrogenase,
NAD-binding; n=4; Chloroflexaceae|Rep:
6-phosphogluconate dehydrogenase, NAD-binding -
Roseiflexus sp. RS-1
Length = 303
Score = 62.9 bits (146), Expect = 1e-08
Identities = 33/79 (41%), Positives = 45/79 (56%)
Frame = +2
Query: 407 GKDGVVAHAKKGSLLIDSSTIDXNVPQQIFPIALEKGLGFTDAPVSGRVMGCSKRYLAFM 586
G+ GV+ A+ GSL+ID STI Q+I E+ + DAPVSG G ++ L+ M
Sbjct: 80 GEGGVIHGARPGSLVIDMSTISPRATQRIAAHLAERHIHMLDAPVSGGSEGAARGTLSIM 139
Query: 587 AGXRKKNFERSLPLLQVMG 643
G FER+LP+ Q MG
Sbjct: 140 VGGDVTQFERALPVFQAMG 158
>UniRef50_P28811 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=72;
Proteobacteria|Rep: 3-hydroxyisobutyrate dehydrogenase -
Pseudomonas aeruginosa
Length = 298
Score = 62.5 bits (145), Expect = 1e-08
Identities = 38/104 (36%), Positives = 52/104 (50%)
Frame = +2
Query: 374 PAIKSCSTCTWGKDGVVAHAKKGSLLIDSSTIDXNVPQQIFPIALEKGLGFTDAPVSGRV 553
PA + + G DG++A LLID STI +++ A KGL DAPVSG V
Sbjct: 66 PAGQHVESLYLGDDGLLARVAGKPLLIDCSTIAPETARKVAEAAAAKGLTLLDAPVSGGV 125
Query: 554 MGCSKRYLAFMAGXRKKNFERSLPLLQVMGANSXTADRSGSXXV 685
G L+F+ G + F R+ P+L+ MG N A G+ V
Sbjct: 126 GGARAGTLSFIVGGPAEGFARARPVLENMGRNIFHAGDHGAGQV 169
Score = 51.6 bits (118), Expect = 3e-05
Identities = 29/75 (38%), Positives = 40/75 (53%)
Frame = +1
Query: 184 NVAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGVTPANSIXXXXXXXXXXX 363
++AFLGLGNMGG MAANL+K G V +D A+ + G A+S
Sbjct: 3 DIAFLGLGNMGGPMAANLLKAGHRVNVFDLQPKAVLGLVEQGAQGADSALQCCEGAEVVI 62
Query: 364 SILTSNKVVLDVYLG 408
S+L + + V +YLG
Sbjct: 63 SMLPAGQHVESLYLG 77
>UniRef50_P31937 Cluster: 3-hydroxyisobutyrate dehydrogenase,
mitochondrial precursor; n=38; Eumetazoa|Rep:
3-hydroxyisobutyrate dehydrogenase, mitochondrial
precursor - Homo sapiens (Human)
Length = 336
Score = 62.5 bits (145), Expect = 1e-08
Identities = 35/81 (43%), Positives = 45/81 (55%)
Frame = +2
Query: 407 GKDGVVAHAKKGSLLIDSSTIDXNVPQQIFPIALEKGLGFTDAPVSGRVMGCSKRYLAFM 586
G +G++ KKGSLLIDSSTID V +++ + G F DAPVSG V L FM
Sbjct: 115 GANGILKKVKKGSLLIDSSTIDPAVSKELAKEVEKMGAVFMDAPVSGGVGAARSGNLTFM 174
Query: 587 AGXRKKNFERSLPLLQVMGAN 649
G + F + LL MG+N
Sbjct: 175 VGGVEDEFAAAQELLGCMGSN 195
Score = 38.7 bits (86), Expect = 0.19
Identities = 23/60 (38%), Positives = 30/60 (50%)
Frame = +1
Query: 106 WPRAQY*STQCLYTAARRAYSSNTDKNVAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDA 285
W R + R+ +S T V F+GLGNMG MA NL+K G+ + YD DA
Sbjct: 17 WSRRLRPAAGSFAAVCSRSVASKTP--VGFIGLGNMGNPMAKNLMKHGYPLIIYDVFPDA 74
Score = 33.9 bits (74), Expect = 5.4
Identities = 13/25 (52%), Positives = 20/25 (80%)
Frame = +3
Query: 705 MLMGLTGMATAECMNMGIKMGLXPK 779
ML+ ++ + TAE MN+GI++GL PK
Sbjct: 214 MLLAISMIGTAEAMNLGIRLGLDPK 238
>UniRef50_A7JGH8 Cluster: Predicted protein; n=1; Francisella
tularensis subsp. novicida GA99-3549|Rep: Predicted
protein - Francisella tularensis subsp. novicida
GA99-3549
Length = 293
Score = 62.1 bits (144), Expect = 2e-08
Identities = 34/90 (37%), Positives = 45/90 (50%)
Frame = +2
Query: 374 PAIKSCSTCTWGKDGVVAHAKKGSLLIDSSTIDXNVPQQIFPIALEKGLGFTDAPVSGRV 553
P S DG++ AK G+++ID+STID N + A + L DAPVSG +
Sbjct: 66 PGPNQVSNVCDSSDGILKIAKAGTIIIDTSTIDANTSVLLAKKAKQNNLHMLDAPVSGGI 125
Query: 554 MGCSKRYLAFMAGXRKKNFERSLPLLQVMG 643
+G L FM G K+ FER L MG
Sbjct: 126 IGAQNATLTFMVGGDKEIFERCKNLFNSMG 155
Score = 52.4 bits (120), Expect = 1e-05
Identities = 26/50 (52%), Positives = 31/50 (62%)
Frame = +1
Query: 181 KNVAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGVTPANSI 330
KN+AF+GLG MG MA NL+ G+ V G+D S D LN NG A SI
Sbjct: 2 KNIAFIGLGCMGLHMAKNLIDNGYKVYGFDMSLDQLNKHQNNGGIAAKSI 51
>UniRef50_Q0SBQ9 Cluster: 2-hydroxy-3-oxopropionate reductase; n=12;
Actinomycetales|Rep: 2-hydroxy-3-oxopropionate reductase
- Rhodococcus sp. (strain RHA1)
Length = 294
Score = 61.7 bits (143), Expect = 2e-08
Identities = 33/90 (36%), Positives = 47/90 (52%)
Frame = +2
Query: 407 GKDGVVAHAKKGSLLIDSSTIDXNVPQQIFPIALEKGLGFTDAPVSGRVMGCSKRYLAFM 586
G+DGV H G+L+ID S+I +V + A E+G DAPVSG G L+ M
Sbjct: 77 GEDGVFEHTPSGALIIDFSSIRPDVTTALAAQATERGFRLIDAPVSGGEAGAVNAALSIM 136
Query: 587 AGXRKKNFERSLPLLQVMGANSXTADRSGS 676
G ++FE + P+L V+G +GS
Sbjct: 137 VGGAPEDFESARPILDVVGKTVVHVGPNGS 166
Score = 42.3 bits (95), Expect = 0.015
Identities = 23/48 (47%), Positives = 28/48 (58%)
Frame = +1
Query: 187 VAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGVTPANSI 330
+AF+GLG MG MA NL K G V GY+ D A + G T A+SI
Sbjct: 4 IAFIGLGIMGSPMACNLAKAGHQVVGYNLIPDRTAALVEAGGTAADSI 51
>UniRef50_Q9K9L1 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=2;
Bacillus|Rep: 3-hydroxyisobutyrate dehydrogenase -
Bacillus halodurans
Length = 299
Score = 61.3 bits (142), Expect = 3e-08
Identities = 32/79 (40%), Positives = 42/79 (53%)
Frame = +2
Query: 407 GKDGVVAHAKKGSLLIDSSTIDXNVPQQIFPIALEKGLGFTDAPVSGRVMGCSKRYLAFM 586
G+DG++A +G +LID ST+D ++ EKG F DAPVSG MG L M
Sbjct: 78 GEDGLIAGLSQGKILIDHSTVDRETNVRVAEQIKEKGGAFLDAPVSGGPMGAKAGTLTIM 137
Query: 587 AGXRKKNFERSLPLLQVMG 643
G +FERS +L G
Sbjct: 138 CGGEADSFERSKEVLGAYG 156
Score = 37.5 bits (83), Expect = 0.44
Identities = 28/98 (28%), Positives = 40/98 (40%), Gaps = 1/98 (1%)
Frame = +1
Query: 181 KNVAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGVTPANSIXXXXXXXXXX 360
+ V F+GLG MG M +LV KGF S+ + A + G S
Sbjct: 3 QKVGFVGLGTMGLPMTKHLVDKGFETYVKSRSRGPIEEAIQYGAIEVESYKELMETADIV 62
Query: 361 XSILTSNKVVLDVYLGQRWR-CGSCEKRIASDRFEYDR 471
+ L + V+DVY G+ G + +I D DR
Sbjct: 63 MTCLPLPETVIDVYEGEDGLIAGLSQGKILIDHSTVDR 100
>UniRef50_Q54CX6 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=3;
cellular organisms|Rep: 3-hydroxyisobutyrate
dehydrogenase - Dictyostelium discoideum AX4
Length = 321
Score = 61.3 bits (142), Expect = 3e-08
Identities = 32/85 (37%), Positives = 47/85 (55%)
Frame = +1
Query: 157 RAYSSNTDKNVAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGVTPANSIXX 336
R S+++ K V F+GLGNMGG A NL+KKG + +D SKD +N + G ANS
Sbjct: 15 RYMSTSSSKTVGFIGLGNMGGHQAINLIKKGHNLIVFDMSKDNMNRLKEKGAKIANSPAE 74
Query: 337 XXXXXXXXXSILTSNKVVLDVYLGQ 411
++L ++ V +VY G+
Sbjct: 75 VAKEADVIVTMLPASAHVKNVYCGE 99
Score = 55.2 bits (127), Expect = 2e-06
Identities = 30/92 (32%), Positives = 45/92 (48%)
Frame = +2
Query: 374 PAIKSCSTCTWGKDGVVAHAKKGSLLIDSSTIDXNVPQQIFPIALEKGLGFTDAPVSGRV 553
PA G++G+ + G+LL+DSSTID +++ IA + D PVSG
Sbjct: 87 PASAHVKNVYCGENGIFQTVRPGTLLLDSSTIDPATAREVASIAKKHQSTMLDCPVSGGT 146
Query: 554 MGCSKRYLAFMAGXRKKNFERSLPLLQVMGAN 649
G L FM G +++F + L+ MG N
Sbjct: 147 GGAEAGTLTFMVGGSEQDFNTAKTYLECMGKN 178
Score = 34.7 bits (76), Expect = 3.1
Identities = 12/29 (41%), Positives = 22/29 (75%)
Frame = +3
Query: 705 MLMGLTGMATAECMNMGIKMGLXPKGLVG 791
+++G++ +A +E MN+G+K G+ PK L G
Sbjct: 197 LVLGISMIAVSEAMNLGVKQGMDPKKLAG 225
>UniRef50_Q0K0E2 Cluster: 3-Hydroxyisobutyrate dehydrogenase; n=1;
Ralstonia eutropha H16|Rep: 3-Hydroxyisobutyrate
dehydrogenase - Ralstonia eutropha (strain ATCC 17699 /
H16 / DSM 428 / Stanier 337)(Cupriavidus necator (strain
ATCC 17699 / H16 / DSM 428 / Stanier337))
Length = 299
Score = 60.9 bits (141), Expect = 4e-08
Identities = 36/96 (37%), Positives = 51/96 (53%)
Frame = +2
Query: 398 CTWGKDGVVAHAKKGSLLIDSSTIDXNVPQQIFPIALEKGLGFTDAPVSGRVMGCSKRYL 577
CT G GV+ A G+LLI+SSTI + + A + G DAPV+G G + L
Sbjct: 76 CTAG--GVLDVAAPGALLIESSTIGPAAARAVAAEAAQAGFAMLDAPVAGGQAGAREARL 133
Query: 578 AFMAGXRKKNFERSLPLLQVMGANSXTADRSGSXXV 685
FM G + F+R+ P+L+ MGA A SG+ +
Sbjct: 134 TFMVGGARTAFDRAEPVLRQMGARIFYAGASGNGQI 169
Score = 46.0 bits (104), Expect = 0.001
Identities = 27/72 (37%), Positives = 38/72 (52%)
Frame = +1
Query: 187 VAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGVTPANSIXXXXXXXXXXXS 366
+AF+GLGNMG MA NLV+ G V+G+D S+ AL A G S+ S
Sbjct: 4 IAFIGLGNMGMPMALNLVRAGHDVQGFDISEAALAGFAGQGGQSQRSVAAAVDGASIVIS 63
Query: 367 ILTSNKVVLDVY 402
I+ + V ++Y
Sbjct: 64 IVRNADDVKNLY 75
>UniRef50_A0JUJ6 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=2;
Micrococcineae|Rep: 3-hydroxyisobutyrate dehydrogenase -
Arthrobacter sp. (strain FB24)
Length = 300
Score = 60.9 bits (141), Expect = 4e-08
Identities = 32/75 (42%), Positives = 43/75 (57%)
Frame = +1
Query: 187 VAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGVTPANSIXXXXXXXXXXXS 366
VA++GLGNMGG M+ANL K G VRG+D + +A+ AA GV P SI +
Sbjct: 4 VAWIGLGNMGGSMSANLAKAGHDVRGFDLNPEAVAAAEAGGVKPVASIAAAVDGADVVFT 63
Query: 367 ILTSNKVVLDVYLGQ 411
+L + VYLG+
Sbjct: 64 MLPKGEHARAVYLGE 78
Score = 60.1 bits (139), Expect = 7e-08
Identities = 32/81 (39%), Positives = 43/81 (53%)
Frame = +2
Query: 407 GKDGVVAHAKKGSLLIDSSTIDXNVPQQIFPIALEKGLGFTDAPVSGRVMGCSKRYLAFM 586
G+DGV+AHA + +LL+DSSTID Q + A G F DAPVSG + G L FM
Sbjct: 77 GEDGVLAHADRRTLLVDSSTIDIASAQALHDAAAAAGFRFVDAPVSGGMSGAKAGTLTFM 136
Query: 587 AGXRKKNFERSLPLLQVMGAN 649
G + ++ M +N
Sbjct: 137 IGGDAGAVAEATEYIRPMASN 157
>UniRef50_Q4FMJ3 Cluster: 6-phosphogluconate dehydrogenase; n=2;
Candidatus Pelagibacter ubique|Rep: 6-phosphogluconate
dehydrogenase - Pelagibacter ubique
Length = 289
Score = 60.5 bits (140), Expect = 5e-08
Identities = 26/79 (32%), Positives = 49/79 (62%)
Frame = +2
Query: 407 GKDGVVAHAKKGSLLIDSSTIDXNVPQQIFPIALEKGLGFTDAPVSGRVMGCSKRYLAFM 586
G D +++ K+G+ +ID S+++ + ++ F I EK + + DAPVSG +G + LA M
Sbjct: 76 GSDEFISNIKEGATVIDMSSVNPVITKKYFKILKEKNINYLDAPVSGGTIGAEEASLAIM 135
Query: 587 AGXRKKNFERSLPLLQVMG 643
G ++ F++ LL+++G
Sbjct: 136 VGGDEETFKQCYDLLKILG 154
Score = 45.2 bits (102), Expect = 0.002
Identities = 23/70 (32%), Positives = 38/70 (54%)
Frame = +1
Query: 181 KNVAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGVTPANSIXXXXXXXXXX 360
+N++F+G+G MG MA NL+K GF +R Y+ S+D + + G + SI
Sbjct: 2 QNISFIGIGLMGFPMAKNLLKSGFNLRAYNRSQDKADRLKEFGAEISTSIKDVVTNSDVI 61
Query: 361 XSILTSNKVV 390
++LT + V
Sbjct: 62 ITMLTDDAAV 71
>UniRef50_Q1QWU9 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=1;
Chromohalobacter salexigens DSM 3043|Rep:
3-hydroxyisobutyrate dehydrogenase - Chromohalobacter
salexigens (strain DSM 3043 / ATCC BAA-138 / NCIMB13768)
Length = 310
Score = 59.7 bits (138), Expect = 9e-08
Identities = 33/102 (32%), Positives = 50/102 (49%)
Frame = +2
Query: 416 GVVAHAKKGSLLIDSSTIDXNVPQQIFPIALEKGLGFTDAPVSGRVMGCSKRYLAFMAGX 595
G++ A KGS+++D+ST D V +++ +E GL + DAPVSG G + L + G
Sbjct: 87 GLLQRAPKGSVIVDTSTSDPAVTRELAGKVVEAGLEWLDAPVSGGPAGAASGALGMLLGG 146
Query: 596 RKKNFERSLPLLQVMGANSXTADRSGSXXVG*XXXXYVDGPH 721
ER P+L+ M A +GS V Y+ H
Sbjct: 147 ESATIERLAPMLEAMSARHTHVGPAGSGHVVKLANNYLCAAH 188
Score = 39.9 bits (89), Expect = 0.082
Identities = 20/46 (43%), Positives = 26/46 (56%)
Frame = +1
Query: 178 DKNVAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGVT 315
D N+ +GLG MGG MA L GFTV G D + A + A G++
Sbjct: 10 DMNIVVIGLGQMGGNMAMTLHAAGFTVTGTDVADAARDNLAARGLS 55
>UniRef50_Q01ZG6 Cluster: 2-hydroxy-3-oxopropionate reductase; n=6;
Bacteria|Rep: 2-hydroxy-3-oxopropionate reductase -
Solibacter usitatus (strain Ellin6076)
Length = 298
Score = 59.7 bits (138), Expect = 9e-08
Identities = 35/97 (36%), Positives = 49/97 (50%)
Frame = +2
Query: 395 TCTWGKDGVVAHAKKGSLLIDSSTIDXNVPQQIFPIALEKGLGFTDAPVSGRVMGCSKRY 574
T G GV+ AK G++++D S+I V Q++ KG+ F DAPVSG
Sbjct: 73 TAVLGPGGVLEGAKAGTVVVDMSSISPMVSQKVAAACAAKGVEFLDAPVSGGEPKAIDGT 132
Query: 575 LAFMAGXRKKNFERSLPLLQVMGANSXTADRSGSXXV 685
LA M G + + FER P+L MGA+ G+ V
Sbjct: 133 LAIMVGGKPEVFERVQPVLAKMGASVTLTGAVGAGNV 169
>UniRef50_A3I4V2 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=1;
Bacillus sp. B14905|Rep: 3-hydroxyisobutyrate
dehydrogenase - Bacillus sp. B14905
Length = 316
Score = 59.3 bits (137), Expect = 1e-07
Identities = 27/80 (33%), Positives = 47/80 (58%)
Frame = +2
Query: 410 KDGVVAHAKKGSLLIDSSTIDXNVPQQIFPIALEKGLGFTDAPVSGRVMGCSKRYLAFMA 589
++G++ HAKKG+LL+D ST++ ++ + A GL + APVSG V+G L M
Sbjct: 98 EEGIIHHAKKGALLVDFSTVNPDLNDSLHKEASTLGLRYLGAPVSGGVIGAVNATLTIMV 157
Query: 590 GXRKKNFERSLPLLQVMGAN 649
G K +++ + + ++G N
Sbjct: 158 GGGKDDYDSASEIFGIVGKN 177
Score = 37.9 bits (84), Expect = 0.33
Identities = 22/78 (28%), Positives = 38/78 (48%)
Frame = +1
Query: 178 DKNVAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGVTPANSIXXXXXXXXX 357
++ + F+GLGNMG M+ NL+K + V G+D + A+ + G S
Sbjct: 21 NRKLGFIGLGNMGLPMSINLLKANYEVYGFDTNAKAVELFTEAGGIGLASAKDVAKQCDV 80
Query: 358 XXSILTSNKVVLDVYLGQ 411
+ L + ++V VYL +
Sbjct: 81 VMTSLPTPQIVEMVYLSE 98
>UniRef50_Q8ES28 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=13;
Bacillaceae|Rep: 3-hydroxyisobutyrate dehydrogenase -
Oceanobacillus iheyensis
Length = 299
Score = 58.4 bits (135), Expect = 2e-07
Identities = 28/92 (30%), Positives = 49/92 (53%)
Frame = +2
Query: 374 PAIKSCSTCTWGKDGVVAHAKKGSLLIDSSTIDXNVPQQIFPIALEKGLGFTDAPVSGRV 553
P+ K+ K G++ H ++ID+ST+ + QQ+ E+ + F APVSG V
Sbjct: 66 PSNKAVEAVYLNKGGLLDHCNSSQVVIDTSTVAPELNQQLEASLSERSIPFLAAPVSGGV 125
Query: 554 MGCSKRYLAFMAGXRKKNFERSLPLLQVMGAN 649
+G + L M G +++ F++ +L V+G N
Sbjct: 126 VGAENQTLTVMVGGKEETFQKVKDILNVIGGN 157
Score = 41.1 bits (92), Expect = 0.036
Identities = 25/75 (33%), Positives = 37/75 (49%)
Frame = +1
Query: 187 VAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGVTPANSIXXXXXXXXXXXS 366
+ F+GLGNMG M+ L+ G+ V G+D +++ K+G A S +
Sbjct: 4 IGFIGLGNMGLPMSIGLMNSGYEVIGFDVNEERSLLFKKSGGNIALSSADLVAESDVILT 63
Query: 367 ILTSNKVVLDVYLGQ 411
L SNK V VYL +
Sbjct: 64 SLPSNKAVEAVYLNK 78
>UniRef50_Q83D20 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=9;
Proteobacteria|Rep: 3-hydroxyisobutyrate dehydrogenase -
Coxiella burnetii
Length = 297
Score = 58.4 bits (135), Expect = 2e-07
Identities = 30/93 (32%), Positives = 48/93 (51%)
Frame = +2
Query: 398 CTWGKDGVVAHAKKGSLLIDSSTIDXNVPQQIFPIALEKGLGFTDAPVSGRVMGCSKRYL 577
C G+ A + ++ IDSS+ID +++ A ++G+ DAPVSG V L
Sbjct: 74 CCLSAKGIFATINRQAIYIDSSSIDIEGSRELHKEAKKRGISMLDAPVSGGVAAAEAAGL 133
Query: 578 AFMAGXRKKNFERSLPLLQVMGANSXTADRSGS 676
FM G K++FER+ +L ++G A G+
Sbjct: 134 TFMVGGEKEDFERAKRVLGILGKKIIYAGSDGA 166
Score = 41.5 bits (93), Expect = 0.027
Identities = 20/47 (42%), Positives = 27/47 (57%)
Frame = +1
Query: 187 VAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGVTPANS 327
+ F+GLG+MG M NL+K V+ YD +A+ A K G T A S
Sbjct: 4 IGFIGLGHMGQPMVNNLIKNNCLVKVYDVIDEAVEKAVKTGATAAAS 50
>UniRef50_Q0QLF5 Cluster: 2-hydroxymethyl glutarate dehydrogenase;
n=1; Eubacterium barkeri|Rep: 2-hydroxymethyl glutarate
dehydrogenase - Eubacterium barkeri (Clostridium
barkeri)
Length = 301
Score = 58.4 bits (135), Expect = 2e-07
Identities = 27/79 (34%), Positives = 45/79 (56%)
Frame = +2
Query: 407 GKDGVVAHAKKGSLLIDSSTIDXNVPQQIFPIALEKGLGFTDAPVSGRVMGCSKRYLAFM 586
G GV++ K G++++D S++ + ++ +A EKG+ + DAPVSG G L M
Sbjct: 80 GPGGVLSACKAGTVIVDMSSVSPSSTLKMAKVAAEKGIDYVDAPVSGGTKGAEAGTLTIM 139
Query: 587 AGXRKKNFERSLPLLQVMG 643
G + FE+ P+L V+G
Sbjct: 140 VGASEAVFEKIQPVLSVIG 158
Score = 35.1 bits (77), Expect = 2.3
Identities = 17/41 (41%), Positives = 24/41 (58%)
Frame = +1
Query: 187 VAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNG 309
+ F+GLG MG MA NL+K+G TV +D + + A G
Sbjct: 7 IGFIGLGAMGKPMAINLLKEGVTVYAFDLMEANVAAVVAQG 47
>UniRef50_Q2JEV5 Cluster: 6-phosphogluconate dehydrogenase,
NAD-binding; n=6; Bacteria|Rep: 6-phosphogluconate
dehydrogenase, NAD-binding - Frankia sp. (strain CcI3)
Length = 302
Score = 58.0 bits (134), Expect = 3e-07
Identities = 28/80 (35%), Positives = 43/80 (53%)
Frame = +2
Query: 407 GKDGVVAHAKKGSLLIDSSTIDXNVPQQIFPIALEKGLGFTDAPVSGRVMGCSKRYLAFM 586
G DGV+ + G++++D +T + ++I E G+GF DAPVSG G L+ M
Sbjct: 77 GADGVLGALRPGAIIVDHTTTSAELAEEIAARTAEVGVGFVDAPVSGGEAGAMAGRLSIM 136
Query: 587 AGXRKKNFERSLPLLQVMGA 646
G + ER+ P+L GA
Sbjct: 137 CGGDPETIERARPVLAAYGA 156
>UniRef50_Q58PL4 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=1;
uncultured proteobacterium DelRiverFos06H03|Rep:
3-hydroxyisobutyrate dehydrogenase - uncultured
proteobacterium DelRiverFos06H03
Length = 299
Score = 56.8 bits (131), Expect = 7e-07
Identities = 28/79 (35%), Positives = 45/79 (56%)
Frame = +2
Query: 407 GKDGVVAHAKKGSLLIDSSTIDXNVPQQIFPIALEKGLGFTDAPVSGRVMGCSKRYLAFM 586
G+ GV+AH K G+ +ID+ST + Q++ +A KG+ F +APV+ V + L+
Sbjct: 81 GEQGVLAHVKAGATVIDTSTSAVELVQELVALAKSKGVDFLEAPVTNAVDMAALGRLSIF 140
Query: 587 AGXRKKNFERSLPLLQVMG 643
G K FE+ P+ V+G
Sbjct: 141 VGGDKDCFEKHKPIFDVIG 159
Score = 41.1 bits (92), Expect = 0.036
Identities = 25/74 (33%), Positives = 35/74 (47%)
Frame = +1
Query: 193 FLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGVTPANSIXXXXXXXXXXXSIL 372
F+G+GNMG MAANLVK G+ V +D S+ G T S+ + L
Sbjct: 10 FIGVGNMGNPMAANLVKAGYPVTVFDVSRAKAENLIALGATWVGSLAEGAVNADVVMASL 69
Query: 373 TSNKVVLDVYLGQR 414
V +V LG++
Sbjct: 70 PGPVQVREVMLGEQ 83
>UniRef50_A3RRS1 Cluster: 2-hydroxy-3-oxopropionate reductase; n=11;
Betaproteobacteria|Rep: 2-hydroxy-3-oxopropionate
reductase - Ralstonia solanacearum UW551
Length = 298
Score = 56.8 bits (131), Expect = 7e-07
Identities = 34/83 (40%), Positives = 45/83 (54%), Gaps = 4/83 (4%)
Frame = +2
Query: 407 GKDGVVAHAKKG----SLLIDSSTIDXNVPQQIFPIALEKGLGFTDAPVSGRVMGCSKRY 574
G DGV+ A +G ++ ID STI ++I GL F DAPVSG MG K
Sbjct: 77 GPDGVIHGAPRGKPGSAVCIDHSTISAVATRRIAAELETAGLDFLDAPVSGGTMGAQKAT 136
Query: 575 LAFMAGXRKKNFERSLPLLQVMG 643
L+ M G + + ER PLLQ++G
Sbjct: 137 LSIMVGGKAEVLERVRPLLQLLG 159
Score = 41.5 bits (93), Expect = 0.027
Identities = 26/74 (35%), Positives = 34/74 (45%)
Frame = +1
Query: 187 VAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGVTPANSIXXXXXXXXXXXS 366
+AF+GLGNMG M +LV G VR Y +A + A G P +S +
Sbjct: 4 IAFIGLGNMGSPMVGHLVAAGHAVRAYVRRPEAADRARALGAEPCDSPADAARDAEVVFT 63
Query: 367 ILTSNKVVLDVYLG 408
+TS V V LG
Sbjct: 64 NVTSTADVEAVLLG 77
>UniRef50_A0QSJ0 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=3;
Bacteria|Rep: 3-hydroxyisobutyrate dehydrogenase -
Mycobacterium smegmatis (strain ATCC 700084 / mc(2)155)
Length = 290
Score = 56.8 bits (131), Expect = 7e-07
Identities = 34/86 (39%), Positives = 44/86 (51%)
Frame = +2
Query: 419 VVAHAKKGSLLIDSSTIDXNVPQQIFPIALEKGLGFTDAPVSGRVMGCSKRYLAFMAGXR 598
V+ A G+L ID+STI + + + ALEKG DAPVSG V G + LAFM G
Sbjct: 78 VLPAAPTGTLFIDTSTISVDDARTVHTQALEKGHAQLDAPVSGGVKGATAGTLAFMVGGE 137
Query: 599 KKNFERSLPLLQVMGANSXTADRSGS 676
ER+ P+L M SG+
Sbjct: 138 DDAVERARPILDPMAGKIIHCGGSGT 163
Score = 52.0 bits (119), Expect = 2e-05
Identities = 24/42 (57%), Positives = 29/42 (69%)
Frame = +1
Query: 187 VAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGV 312
+AFLGLG+MGG MAANL G TVRG+DP + AA G+
Sbjct: 4 IAFLGLGHMGGPMAANLAAAGHTVRGFDPMPASREAAEAKGI 45
>UniRef50_Q03UI4 Cluster: 3-hydroxyisobutyrate dehydrogenase related
enzyme; n=2; Lactobacillales|Rep: 3-hydroxyisobutyrate
dehydrogenase related enzyme - Leuconostoc mesenteroides
subsp. mesenteroides (strain ATCC 8293 /NCDO 523)
Length = 287
Score = 56.4 bits (130), Expect = 9e-07
Identities = 30/88 (34%), Positives = 46/88 (52%)
Frame = +2
Query: 410 KDGVVAHAKKGSLLIDSSTIDXNVPQQIFPIALEKGLGFTDAPVSGRVMGCSKRYLAFMA 589
+DGV A AK+GS+L+D +T + +Q+ + G DAPVSG +G LA M
Sbjct: 77 EDGVFAGAKEGSILVDMTTSTPRLAEQLAQTGADLGFKVLDAPVSGGDIGAKNGTLAIMV 136
Query: 590 GXRKKNFERSLPLLQVMGANSXTADRSG 673
G ++ + P+L V+G A +G
Sbjct: 137 GGEQQVLDEIKPVLSVIGQQIVFAGSAG 164
>UniRef50_A6P2M7 Cluster: Putative uncharacterized protein; n=2;
Bacteria|Rep: Putative uncharacterized protein -
Bacteroides capillosus ATCC 29799
Length = 321
Score = 56.4 bits (130), Expect = 9e-07
Identities = 27/80 (33%), Positives = 46/80 (57%)
Frame = +2
Query: 404 WGKDGVVAHAKKGSLLIDSSTIDXNVPQQIFPIALEKGLGFTDAPVSGRVMGCSKRYLAF 583
+G G++++A+ G+L++D +T + ++I+ KGL DAPV+G G L+
Sbjct: 110 FGDGGIISNAQPGALIVDMTTSSPALAERIWEAGKAKGLRPLDAPVTGGDTGAKAGTLSI 169
Query: 584 MAGXRKKNFERSLPLLQVMG 643
+ G K +F+ LPL Q MG
Sbjct: 170 LVGGDKVDFDACLPLFQAMG 189
Score = 38.3 bits (85), Expect = 0.25
Identities = 22/74 (29%), Positives = 35/74 (47%)
Frame = +1
Query: 187 VAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGVTPANSIXXXXXXXXXXXS 366
+AF+G+G MG M NL+K G+++ Y +K G A+++ S
Sbjct: 38 IAFIGVGIMGKSMVRNLMKAGYSLTIYSRTKAKCEDVIAEGAVWADTVADCVRDAEAVFS 97
Query: 367 ILTSNKVVLDVYLG 408
I+ K V +VY G
Sbjct: 98 IVGYPKDVEEVYFG 111
>UniRef50_A1SIN3 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=1;
Nocardioides sp. JS614|Rep: 3-hydroxyisobutyrate
dehydrogenase - Nocardioides sp. (strain BAA-499 /
JS614)
Length = 308
Score = 56.4 bits (130), Expect = 9e-07
Identities = 30/78 (38%), Positives = 43/78 (55%)
Frame = +2
Query: 410 KDGVVAHAKKGSLLIDSSTIDXNVPQQIFPIALEKGLGFTDAPVSGRVMGCSKRYLAFMA 589
+ GV+ + G+L+IDSS+ID + A G+ F DAPVSG V G + L FM
Sbjct: 81 ESGVLNYLAPGALVIDSSSIDVANCLAVHESAASAGIAFLDAPVSGGVGGAAAGTLTFMV 140
Query: 590 GXRKKNFERSLPLLQVMG 643
G + + R+ PL + MG
Sbjct: 141 GGDEAHVRRAWPLFEAMG 158
Score = 49.2 bits (112), Expect = 1e-04
Identities = 24/76 (31%), Positives = 38/76 (50%)
Frame = +1
Query: 181 KNVAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGVTPANSIXXXXXXXXXX 360
+ +AF+GLGNMG MA NL+ GF V G+D +A+ G+ A +
Sbjct: 2 ERIAFIGLGNMGNSMAKNLIAAGFDVVGFDADSRTNQRSAETGIPVAADVVDAVTGADVV 61
Query: 361 XSILTSNKVVLDVYLG 408
++L + ++ V LG
Sbjct: 62 ITMLPNGDILRQVLLG 77
>UniRef50_A1QPH6 Cluster: 3-hydroxyisobutyrate dehydrogenase mmsB;
n=5; Mycobacterium|Rep: 3-hydroxyisobutyrate
dehydrogenase mmsB - Mycobacterium tuberculosis (strain
F11)
Length = 315
Score = 56.0 bits (129), Expect = 1e-06
Identities = 30/72 (41%), Positives = 40/72 (55%)
Frame = +1
Query: 187 VAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGVTPANSIXXXXXXXXXXXS 366
+AFLGLGNMG M+ANLV G VRG+DP+ A + AA +GV S +
Sbjct: 4 IAFLGLGNMGAPMSANLVGAGHVVRGFDPAPTAASGAAAHGVAVFRSAPEAVAEADVVIT 63
Query: 367 ILTSNKVVLDVY 402
+L + +VV Y
Sbjct: 64 MLPTGEVVRRCY 75
Score = 54.4 bits (125), Expect = 4e-06
Identities = 30/86 (34%), Positives = 45/86 (52%)
Frame = +2
Query: 419 VVAHAKKGSLLIDSSTIDXNVPQQIFPIALEKGLGFTDAPVSGRVMGCSKRYLAFMAGXR 598
V+A A+ +L IDSSTI +++ +A G+ DAPVSG V G + LAFM G
Sbjct: 78 VLAAARPATLFIDSSTISVTDAREVHALAESHGMLQLDAPVSGGVKGAAAATLAFMVGGD 137
Query: 599 KKNFERSLPLLQVMGANSXTADRSGS 676
+ R+ P+L+ M +G+
Sbjct: 138 ESTLRRARPVLEPMAGKIIHCGAAGA 163
>UniRef50_Q22B54 Cluster: 3-hydroxyisobutyrate dehydrogenase family
protein; n=1; Tetrahymena thermophila SB210|Rep:
3-hydroxyisobutyrate dehydrogenase family protein -
Tetrahymena thermophila SB210
Length = 316
Score = 56.0 bits (129), Expect = 1e-06
Identities = 35/105 (33%), Positives = 51/105 (48%), Gaps = 1/105 (0%)
Frame = +2
Query: 374 PAIKSCSTCTWGKDGVVAHAKKGSLLIDSSTIDXNVPQQIFPIALEKGLGFTDAPVSGRV 553
P S+ G++G+ + K SL IDSSTI + +I+ A + + DAPVSG V
Sbjct: 82 PNSSHVSSVLEGENGLFQKSAKNSLFIDSSTISYHAAIKIYENAKKVNQRYIDAPVSGGV 141
Query: 554 MGCSKRYLAFMAGXRKKN-FERSLPLLQVMGANSXTADRSGSXXV 685
+ L FM G K F+ LLQ MG N ++ G+ +
Sbjct: 142 GAATAGTLTFMVGAENKELFQECKNLLQHMGKNIANCEKPGAGSI 186
Score = 50.4 bits (115), Expect = 6e-05
Identities = 28/78 (35%), Positives = 41/78 (52%), Gaps = 1/78 (1%)
Frame = +1
Query: 181 KNVAFLGLGNMGGFMAANLVKK-GFTVRGYDPSKDALNAAAKNGVTPANSIXXXXXXXXX 357
+ V F+GLGNMGG MA NL +K GF V +D +KD+L AK G+ +
Sbjct: 17 ETVGFIGLGNMGGPMALNLARKGGFEVIAFDVNKDSLKKYAKEGLAVCEDVTVLARKANK 76
Query: 358 XXSILTSNKVVLDVYLGQ 411
++L ++ V V G+
Sbjct: 77 FVTMLPNSSHVSSVLEGE 94
>UniRef50_P63936 Cluster: Probable 3-hydroxyisobutyrate
dehydrogenase; n=25; Bacteria|Rep: Probable
3-hydroxyisobutyrate dehydrogenase - Mycobacterium bovis
Length = 294
Score = 56.0 bits (129), Expect = 1e-06
Identities = 30/72 (41%), Positives = 40/72 (55%)
Frame = +1
Query: 187 VAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGVTPANSIXXXXXXXXXXXS 366
+AFLGLGNMG M+ANLV G VRG+DP+ A + AA +GV S +
Sbjct: 4 IAFLGLGNMGAPMSANLVGAGHVVRGFDPAPTAASGAAAHGVAVFRSAPEAVAEADVVIT 63
Query: 367 ILTSNKVVLDVY 402
+L + +VV Y
Sbjct: 64 MLPTGEVVRRCY 75
Score = 54.4 bits (125), Expect = 4e-06
Identities = 30/86 (34%), Positives = 45/86 (52%)
Frame = +2
Query: 419 VVAHAKKGSLLIDSSTIDXNVPQQIFPIALEKGLGFTDAPVSGRVMGCSKRYLAFMAGXR 598
V+A A+ +L IDSSTI +++ +A G+ DAPVSG V G + LAFM G
Sbjct: 78 VLAAARPATLFIDSSTISVTDAREVHALAESHGMLQLDAPVSGGVKGAAAATLAFMVGGD 137
Query: 599 KKNFERSLPLLQVMGANSXTADRSGS 676
+ R+ P+L+ M +G+
Sbjct: 138 ESTLRRARPVLEPMAGKIIHCGAAGA 163
>UniRef50_Q92D17 Cluster: Lin1004 protein; n=10; Bacilli|Rep:
Lin1004 protein - Listeria innocua
Length = 286
Score = 55.6 bits (128), Expect = 2e-06
Identities = 29/90 (32%), Positives = 49/90 (54%)
Frame = +2
Query: 407 GKDGVVAHAKKGSLLIDSSTIDXNVPQQIFPIALEKGLGFTDAPVSGRVMGCSKRYLAFM 586
G++G + + K GS+ ID +T + ++I EKG+G DAPVSG +G LA M
Sbjct: 77 GENGFLDNLKAGSVAIDMTTSSPALAKKIAEAGHEKGIGVLDAPVSGGDIGAKNGTLAIM 136
Query: 587 AGXRKKNFERSLPLLQVMGANSXTADRSGS 676
G + F + P+ +++G++ +GS
Sbjct: 137 VGGAEDVFLKVKPIFEILGSSVILQGDAGS 166
>UniRef50_Q5WBB8 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=1;
Bacillus clausii KSM-K16|Rep: 3-hydroxyisobutyrate
dehydrogenase - Bacillus clausii (strain KSM-K16)
Length = 283
Score = 55.2 bits (127), Expect = 2e-06
Identities = 30/90 (33%), Positives = 42/90 (46%)
Frame = +2
Query: 407 GKDGVVAHAKKGSLLIDSSTIDXNVPQQIFPIALEKGLGFTDAPVSGRVMGCSKRYLAFM 586
GK+GV+ H + G L+D ST D + A KG+ + D PVSG G L M
Sbjct: 77 GKEGVLCHLQTGGFLLDLSTTDVQTTLAMEKAAAAKGIYYLDCPVSGGPAGADAGTLTIM 136
Query: 587 AGXRKKNFERSLPLLQVMGANSXTADRSGS 676
G K+ + PLL ++G SG+
Sbjct: 137 VGGDKQAYFSVKPLLDILGDTILYVGDSGA 166
>UniRef50_A4IN46 Cluster: 3-hydroxyisobutyrate dehydrogenase-like
protein; n=2; Geobacillus|Rep: 3-hydroxyisobutyrate
dehydrogenase-like protein - Geobacillus
thermodenitrificans (strain NG80-2)
Length = 304
Score = 55.2 bits (127), Expect = 2e-06
Identities = 31/105 (29%), Positives = 51/105 (48%)
Frame = +2
Query: 407 GKDGVVAHAKKGSLLIDSSTIDXNVPQQIFPIALEKGLGFTDAPVSGRVMGCSKRYLAFM 586
G+ GV++ A++G + +D +T+ + + A E+G+ + DAPVSG G + L M
Sbjct: 77 GEGGVLSAARRGVICLDFTTVGPKTSRFVAGRAGERGVAYLDAPVSGGPEGAEQGTLTIM 136
Query: 587 AGXRKKNFERSLPLLQVMGANSXTADRSGSXXVG*XXXXYVDGPH 721
G + +ER PLL V+G SG+ Y+ H
Sbjct: 137 VGGDQAAWERVRPLLSVLGKTVEYLGESGAGSAAKILNQYLVAVH 181
>UniRef50_Q1QWQ5 Cluster: 6-phosphogluconate dehydrogenase,
NAD-binding; n=4; Proteobacteria|Rep: 6-phosphogluconate
dehydrogenase, NAD-binding - Chromohalobacter salexigens
(strain DSM 3043 / ATCC BAA-138 / NCIMB13768)
Length = 315
Score = 54.8 bits (126), Expect = 3e-06
Identities = 30/85 (35%), Positives = 41/85 (48%)
Frame = +2
Query: 389 CSTCTWGKDGVVAHAKKGSLLIDSSTIDXNVPQQIFPIALEKGLGFTDAPVSGRVMGCSK 568
C G +GV+AH + L+ S+I + Q+ A +G+G+ DAPVSG G
Sbjct: 93 CDDILLGPEGVIAHMAPHATLVVMSSIPVDTAQRQAQAAEARGIGYLDAPVSGGERGAID 152
Query: 569 RYLAFMAGXRKKNFERSLPLLQVMG 643
LA M G FER PL +G
Sbjct: 153 GTLAIMVGGDPATFERHRPLFAPLG 177
>UniRef50_A5VEA3 Cluster: 2-hydroxy-3-oxopropionate reductase; n=1;
Sphingomonas wittichii RW1|Rep:
2-hydroxy-3-oxopropionate reductase - Sphingomonas
wittichii RW1
Length = 264
Score = 54.8 bits (126), Expect = 3e-06
Identities = 26/90 (28%), Positives = 47/90 (52%)
Frame = +2
Query: 407 GKDGVVAHAKKGSLLIDSSTIDXNVPQQIFPIALEKGLGFTDAPVSGRVMGCSKRYLAFM 586
G+DGV+A A+ G +++ S++ + + ++G+ DAPVSG G R ++FM
Sbjct: 76 GEDGVLASARPGLIVVLHSSVSTDTIAEAAKATRDRGVVLVDAPVSGGAQGARARTMSFM 135
Query: 587 AGXRKKNFERSLPLLQVMGANSXTADRSGS 676
G + +R PL ++ G N +G+
Sbjct: 136 VGGEEAALDRCQPLFELSGPNILRTGPAGT 165
>UniRef50_A0UF54 Cluster: 6-phosphogluconate dehydrogenase,
NAD-binding; n=1; Burkholderia multivorans ATCC
17616|Rep: 6-phosphogluconate dehydrogenase, NAD-binding
- Burkholderia multivorans ATCC 17616
Length = 289
Score = 54.8 bits (126), Expect = 3e-06
Identities = 29/105 (27%), Positives = 49/105 (46%)
Frame = +2
Query: 407 GKDGVVAHAKKGSLLIDSSTIDXNVPQQIFPIALEKGLGFTDAPVSGRVMGCSKRYLAFM 586
G GV +HAK+G ++ID++T D N +++ G+GF D PVSG G + + +
Sbjct: 77 GDGGVASHAKRGLIVIDTTTADPNSTRKVAAALDAHGIGFIDGPVSGGPKGAATATMTMV 136
Query: 587 AGXRKKNFERSLPLLQVMGANSXTADRSGSXXVG*XXXXYVDGPH 721
G ++ P+L + A +G+ V + G H
Sbjct: 137 LGGADEHIAAVQPVLSAISAKQVHVGPAGAGHVTKLLNNLLTGVH 181
Score = 46.4 bits (105), Expect = 0.001
Identities = 25/76 (32%), Positives = 39/76 (51%)
Frame = +1
Query: 181 KNVAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGVTPANSIXXXXXXXXXX 360
K V +GLGNMG +A++L + GF V G+D + +++ A GV P S+
Sbjct: 2 KTVGVIGLGNMGRGIASSLKRAGFDVLGFDANAESVRQLADEGVRPCASVAEIASAVDVL 61
Query: 361 XSILTSNKVVLDVYLG 408
L ++ +V V LG
Sbjct: 62 ILSLPTSAIVEAVVLG 77
>UniRef50_A0K0Z6 Cluster: 6-phosphogluconate dehydrogenase,
NAD-binding precursor; n=2; Micrococcineae|Rep:
6-phosphogluconate dehydrogenase, NAD-binding precursor
- Arthrobacter sp. (strain FB24)
Length = 301
Score = 54.8 bits (126), Expect = 3e-06
Identities = 26/53 (49%), Positives = 34/53 (64%)
Frame = +1
Query: 172 NTDKNVAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGVTPANSI 330
NT +A +GLG MGG MAA L K G+ V G+DPS+ A AAA+ G+ S+
Sbjct: 2 NTSTRIAVIGLGAMGGAMAATLHKAGWDVTGFDPSEAARTAAAQTGIATTASL 54
>UniRef50_Q5L168 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=15;
Bacteria|Rep: 3-hydroxyisobutyrate dehydrogenase -
Geobacillus kaustophilus
Length = 288
Score = 54.4 bits (125), Expect = 4e-06
Identities = 27/82 (32%), Positives = 46/82 (56%)
Frame = +2
Query: 404 WGKDGVVAHAKKGSLLIDSSTIDXNVPQQIFPIALEKGLGFTDAPVSGRVMGCSKRYLAF 583
+G+ G++ +A+ G+ +ID +T + Q I+ A +KG+ DAPVSG +G + L
Sbjct: 76 FGEGGILENARPGTYVIDMTTSTPTLAQSIYEAAKQKGIHALDAPVSGGDIGAREGTLTI 135
Query: 584 MAGXRKKNFERSLPLLQVMGAN 649
M G + F P+L+ +G N
Sbjct: 136 MVGGDEDVFLACKPILERLGTN 157
>UniRef50_Q12CU4 Cluster: 2-hydroxy-3-oxopropionate reductase; n=17;
Proteobacteria|Rep: 2-hydroxy-3-oxopropionate reductase
- Polaromonas sp. (strain JS666 / ATCC BAA-500)
Length = 298
Score = 54.4 bits (125), Expect = 4e-06
Identities = 30/76 (39%), Positives = 40/76 (52%)
Frame = +2
Query: 416 GVVAHAKKGSLLIDSSTIDXNVPQQIFPIALEKGLGFTDAPVSGRVMGCSKRYLAFMAGX 595
GV A K GSL +D ++I + G+ D PVSG +G + L MAG
Sbjct: 87 GVAAAMKPGSLFLDMASITPREARDHAARLGALGIAHLDTPVSGGTVGAEQGTLVIMAGG 146
Query: 596 RKKNFERSLPLLQVMG 643
+ +FERSLPLL+V G
Sbjct: 147 KPADFERSLPLLKVFG 162
>UniRef50_A0LMG6 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=9;
cellular organisms|Rep: 3-hydroxyisobutyrate
dehydrogenase - Syntrophobacter fumaroxidans (strain DSM
10017 / MPOB)
Length = 309
Score = 54.4 bits (125), Expect = 4e-06
Identities = 28/91 (30%), Positives = 51/91 (56%)
Frame = +2
Query: 404 WGKDGVVAHAKKGSLLIDSSTIDXNVPQQIFPIALEKGLGFTDAPVSGRVMGCSKRYLAF 583
+G++G++ A+ G +L+D +T + ++ ++I A E+G DAPVSG +G L+
Sbjct: 88 FGRNGLLQAARPGIILVDMTTTEPSLAREIHQAAGEQGAFAVDAPVSGGDVGARNAALSI 147
Query: 584 MAGXRKKNFERSLPLLQVMGANSXTADRSGS 676
M G ++ + P+L+ MG N +GS
Sbjct: 148 MLGGDREVVDAIRPILEAMGKNLVYLGPAGS 178
>UniRef50_Q55702 Cluster: Uncharacterized oxidoreductase slr0229;
n=4; Cyanobacteria|Rep: Uncharacterized oxidoreductase
slr0229 - Synechocystis sp. (strain PCC 6803)
Length = 290
Score = 54.4 bits (125), Expect = 4e-06
Identities = 31/90 (34%), Positives = 45/90 (50%)
Frame = +2
Query: 407 GKDGVVAHAKKGSLLIDSSTIDXNVPQQIFPIALEKGLGFTDAPVSGRVMGCSKRYLAFM 586
G G+ +AK +L+ID STI ++ +GL F DAPV+G +G L M
Sbjct: 81 GSGGIAEYAKPQALIIDCSTIGKTAAYELATNLKLQGLRFLDAPVTGGDVGAINGTLTIM 140
Query: 587 AGXRKKNFERSLPLLQVMGANSXTADRSGS 676
G +FE +LP+L+ +G SGS
Sbjct: 141 VGGDISDFEEALPVLKSIGEKIVHCGPSGS 170
Score = 39.5 bits (88), Expect = 0.11
Identities = 26/76 (34%), Positives = 36/76 (47%), Gaps = 2/76 (2%)
Frame = +1
Query: 187 VAFLGLGNMGGFMAANLVKKGFTVRGYDPS--KDALNAAAKNGVTPANSIXXXXXXXXXX 360
+A GLG MG MA NLVK G+ GY+ + + ++ AAK GV SI
Sbjct: 6 IAVFGLGVMGSPMAQNLVKNGYQTVGYNRTLERPSVQEAAKAGVKVVTSIAVAAANADII 65
Query: 361 XSILTSNKVVLDVYLG 408
+ + K V + LG
Sbjct: 66 LTCVGDEKDVQQLILG 81
>UniRef50_A5GPC0 Cluster: Hydroxyacid dehydrogenase/reductase family
protein; n=14; Cyanobacteria|Rep: Hydroxyacid
dehydrogenase/reductase family protein - Synechococcus
sp. (strain WH7803)
Length = 302
Score = 54.0 bits (124), Expect = 5e-06
Identities = 25/82 (30%), Positives = 44/82 (53%)
Frame = +2
Query: 404 WGKDGVVAHAKKGSLLIDSSTIDXNVPQQIFPIALEKGLGFTDAPVSGRVMGCSKRYLAF 583
WG +G +GSL+ID STI + Q++ +G+ + DAPV+G G L
Sbjct: 90 WGDNGAGPALAEGSLVIDCSTISPSTSQRMARRLAHRGVRYLDAPVTGGTEGAKAGTLTV 149
Query: 584 MAGXRKKNFERSLPLLQVMGAN 649
+ G + +R++P+L+ +G +
Sbjct: 150 LCGGSDADLDRAMPVLETIGGS 171
>UniRef50_A3VLN6 Cluster: Oxidoreductase; n=1; Rhodobacterales
bacterium HTCC2654|Rep: Oxidoreductase - Rhodobacterales
bacterium HTCC2654
Length = 293
Score = 54.0 bits (124), Expect = 5e-06
Identities = 29/102 (28%), Positives = 49/102 (48%), Gaps = 1/102 (0%)
Frame = +2
Query: 383 KSCSTCTWGKDGVVAHAKKGSLLIDSSTIDXNVPQQIFP-IALEKGLGFTDAPVSGRVMG 559
K+ +G DG+V + ++++D ST+ + +QI + E G + DAPVSG + G
Sbjct: 68 KALDAVLFGSDGIVGAGRVPAMIVDHSTVPPDATRQIAARVRAEAGAAWVDAPVSGGLAG 127
Query: 560 CSKRYLAFMAGXRKKNFERSLPLLQVMGANSXTADRSGSXXV 685
+ LA G + R+ P+L +G +GS V
Sbjct: 128 AAAGQLAIFVGGEDADVTRAWPVLTTLGTTVTHLGPTGSGQV 169
>UniRef50_Q67QX0 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=1;
Symbiobacterium thermophilum|Rep: 3-hydroxyisobutyrate
dehydrogenase - Symbiobacterium thermophilum
Length = 294
Score = 53.6 bits (123), Expect = 6e-06
Identities = 29/71 (40%), Positives = 37/71 (52%)
Frame = +2
Query: 431 AKKGSLLIDSSTIDXNVPQQIFPIALEKGLGFTDAPVSGRVMGCSKRYLAFMAGXRKKNF 610
A+ G + +D STI ++I + EKG+ F DAPVSG G L M G + F
Sbjct: 83 AQPGDIFVDHSTIGVRDAKRIAAMCAEKGVQFIDAPVSGGPWGAEAGTLTIMCGGDRAAF 142
Query: 611 ERSLPLLQVMG 643
E LP LQV G
Sbjct: 143 EAVLPYLQVEG 153
Score = 37.9 bits (84), Expect = 0.33
Identities = 17/42 (40%), Positives = 25/42 (59%)
Frame = +1
Query: 184 NVAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNG 309
N+ F+GLG MG MA NL++ G TV Y+ S+ ++ G
Sbjct: 4 NLGFIGLGRMGRHMARNLIRAGHTVTLYNRSQAVVDELVAEG 45
>UniRef50_Q97XZ7 Cluster: Oxidoreductase; n=6; Thermoprotei|Rep:
Oxidoreductase - Sulfolobus solfataricus
Length = 289
Score = 53.6 bits (123), Expect = 6e-06
Identities = 27/82 (32%), Positives = 44/82 (53%)
Frame = +2
Query: 404 WGKDGVVAHAKKGSLLIDSSTIDXNVPQQIFPIALEKGLGFTDAPVSGRVMGCSKRYLAF 583
+G++GVV K+G + +D ST +++ E G+ F DAPV+G G + L
Sbjct: 75 FGENGVVKSNKRGLIFVDMSTNSPEFAKKVTKRLSEYGMEFLDAPVTGGDKGAREGTLTI 134
Query: 584 MAGXRKKNFERSLPLLQVMGAN 649
M G ++ F+R P+ + MG N
Sbjct: 135 MVGGKEDVFKRVEPIFKAMGKN 156
>UniRef50_Q9SUC0 Cluster: Probable 3-hydroxyisobutyrate
dehydrogenase, mitochondrial precursor; n=13;
Magnoliophyta|Rep: Probable 3-hydroxyisobutyrate
dehydrogenase, mitochondrial precursor - Arabidopsis
thaliana (Mouse-ear cress)
Length = 347
Score = 53.6 bits (123), Expect = 6e-06
Identities = 28/90 (31%), Positives = 48/90 (53%)
Frame = +1
Query: 139 LYTAARRAYSSNTDKNVAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGVTP 318
L+ + + +SN +NV F+GLGNMG M NL++ G+ V +D ++D + + GV+
Sbjct: 24 LHRFSSSSQNSNQFQNVGFIGLGNMGFRMVNNLIRAGYKVTVHDINRDVMKMFTEMGVSS 83
Query: 319 ANSIXXXXXXXXXXXSILTSNKVVLDVYLG 408
+ ++L S+ V+DVY G
Sbjct: 84 RETPYEVAQDSEVVITMLPSSSHVMDVYTG 113
Score = 37.1 bits (82), Expect = 0.58
Identities = 29/88 (32%), Positives = 38/88 (43%), Gaps = 10/88 (11%)
Frame = +2
Query: 443 SLLIDSSTIDXNVPQQIFPIALEKGLG----------FTDAPVSGRVMGCSKRYLAFMAG 592
+L IDSSTID ++I L DAPVSG V+ L FM G
Sbjct: 127 ALFIDSSTIDPQTTRKISLAVSNCNLKEKRDNWEKPVMLDAPVSGGVLAAEAGTLTFMVG 186
Query: 593 XRKKNFERSLPLLQVMGANSXTADRSGS 676
+ + + P+LQ MG S SG+
Sbjct: 187 GPEDAYLAARPILQSMGRTSIYCGGSGN 214
>UniRef50_A6GTB5 Cluster: 6-phosphogluconate dehydrogenase,
NAD-binding protein; n=1; Limnobacter sp. MED105|Rep:
6-phosphogluconate dehydrogenase, NAD-binding protein -
Limnobacter sp. MED105
Length = 299
Score = 53.2 bits (122), Expect = 8e-06
Identities = 29/87 (33%), Positives = 42/87 (48%)
Frame = +2
Query: 416 GVVAHAKKGSLLIDSSTIDXNVPQQIFPIALEKGLGFTDAPVSGRVMGCSKRYLAFMAGX 595
G+ HA+ GS+++D STID I +G+ + D PVSG G L+ MAG
Sbjct: 87 GIAQHAQPGSIIVDFSTIDAAAVADIARQLKSRGVDYIDCPVSGGAAGARAATLSMMAGG 146
Query: 596 RKKNFERSLPLLQVMGANSXTADRSGS 676
F R P+L+ +G SG+
Sbjct: 147 DLAAFNRIEPMLKHLGKTIRHVGPSGA 173
Score = 39.5 bits (88), Expect = 0.11
Identities = 20/52 (38%), Positives = 27/52 (51%)
Frame = +1
Query: 175 TDKNVAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGVTPANSI 330
T + F+GLGNMG MA +L K G+TV + + A A + P SI
Sbjct: 7 TLNTIGFIGLGNMGAAMAGHLCKAGYTVLAWARNASTFEALADIPLVPQPSI 58
>UniRef50_A2U9T6 Cluster: 6-phosphogluconate dehydrogenase,
NAD-binding; n=2; Bacillaceae|Rep: 6-phosphogluconate
dehydrogenase, NAD-binding - Bacillus coagulans 36D1
Length = 294
Score = 53.2 bits (122), Expect = 8e-06
Identities = 28/79 (35%), Positives = 42/79 (53%)
Frame = +2
Query: 407 GKDGVVAHAKKGSLLIDSSTIDXNVPQQIFPIALEKGLGFTDAPVSGRVMGCSKRYLAFM 586
G+DGV+A KG ++D ST+ + + EK F DAPVSG V + L +
Sbjct: 81 GEDGVLAGLTKGKTVVDMSTVSPSDSIRFAKWVEEKRGHFIDAPVSGSVQPAKEGNLVIL 140
Query: 587 AGXRKKNFERSLPLLQVMG 643
AG RK+ + P+ +V+G
Sbjct: 141 AGGRKEEIDAVRPMFEVLG 159
>UniRef50_Q9A8J9 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=24;
Alphaproteobacteria|Rep: 3-hydroxyisobutyrate
dehydrogenase - Caulobacter crescentus (Caulobacter
vibrioides)
Length = 298
Score = 52.4 bits (120), Expect = 1e-05
Identities = 27/64 (42%), Positives = 36/64 (56%)
Frame = +2
Query: 419 VVAHAKKGSLLIDSSTIDXNVPQQIFPIALEKGLGFTDAPVSGRVMGCSKRYLAFMAGXR 598
++ +A K +LLID STID + + + A E G F DAPVSG +M LAFM G
Sbjct: 79 ILPNAPKSALLIDCSTIDVDSARVVARQAAEAGFRFADAPVSGGIMAAEAGTLAFMVGCE 138
Query: 599 KKNF 610
+F
Sbjct: 139 ASDF 142
Score = 46.4 bits (105), Expect = 0.001
Identities = 28/75 (37%), Positives = 36/75 (48%)
Frame = +1
Query: 187 VAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGVTPANSIXXXXXXXXXXXS 366
+AF+GLGNMGG MAAN K VR +D S A+ A G A S+ +
Sbjct: 4 IAFIGLGNMGGGMAANQAKAQHQVRAFDLSAAAVERAVAAGCLAAASVAEAVAEAEIVIT 63
Query: 367 ILTSNKVVLDVYLGQ 411
+L + V VY Q
Sbjct: 64 MLPAGPHVRAVYAEQ 78
>UniRef50_Q183P5 Cluster: 2-hydroxy-3-oxopropionate reductase; n=5;
Bacteria|Rep: 2-hydroxy-3-oxopropionate reductase -
Clostridium difficile (strain 630)
Length = 296
Score = 52.4 bits (120), Expect = 1e-05
Identities = 29/94 (30%), Positives = 49/94 (52%)
Frame = +2
Query: 404 WGKDGVVAHAKKGSLLIDSSTIDXNVPQQIFPIALEKGLGFTDAPVSGRVMGCSKRYLAF 583
+G DG+ K+GS+++D S++ + GL F D+PVSG LAF
Sbjct: 74 FGMDGLAKTLKEGSIVVDMSSVTPTESILCANKLKDMGLEFIDSPVSGGEPKAIDGTLAF 133
Query: 584 MAGXRKKNFERSLPLLQVMGANSXTADRSGSXXV 685
MAG +++ +++ P +MG++S +GS V
Sbjct: 134 MAGGKEEIYKKVEPFFNIMGSSSILIGDNGSGSV 167
>UniRef50_A0N0V2 Cluster: BtdhL; n=1; Azoarcus anaerobius|Rep: BtdhL
- Azoarcus anaerobius
Length = 303
Score = 52.4 bits (120), Expect = 1e-05
Identities = 29/76 (38%), Positives = 39/76 (51%)
Frame = +2
Query: 416 GVVAHAKKGSLLIDSSTIDXNVPQQIFPIALEKGLGFTDAPVSGRVMGCSKRYLAFMAGX 595
GV A G + ID ST+ + ++I A KG+ + APVSG + L +A
Sbjct: 85 GVFEAATPGMVFIDMSTVSPALSERIAAAASAKGIHYLRAPVSGSTTTAAAGALTILASG 144
Query: 596 RKKNFERSLPLLQVMG 643
K +ER LPLLQ MG
Sbjct: 145 PKDAYERCLPLLQAMG 160
Score = 36.7 bits (81), Expect = 0.77
Identities = 19/51 (37%), Positives = 27/51 (52%)
Frame = +1
Query: 178 DKNVAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGVTPANSI 330
D V ++GLG MG MAANL+ G + Y+ S +A + G A S+
Sbjct: 6 DTRVGWIGLGKMGTPMAANLLAAGHAITVYNRSAARADALVEKGAALAPSV 56
>UniRef50_Q930C6 Cluster: Probable; n=8; Alphaproteobacteria|Rep:
Probable - Rhizobium meliloti (Sinorhizobium meliloti)
Length = 295
Score = 52.0 bits (119), Expect = 2e-05
Identities = 29/82 (35%), Positives = 47/82 (57%)
Frame = +2
Query: 404 WGKDGVVAHAKKGSLLIDSSTIDXNVPQQIFPIALEKGLGFTDAPVSGRVMGCSKRYLAF 583
+G GV A A+ G+L+ID S+ID N +Q+ A EKGL + D+P+SG L
Sbjct: 77 FGDAGVAAGAQAGTLIIDMSSIDPNATKQLAADAAEKGLRWVDSPLSGGAPKALIGELTL 136
Query: 584 MAGXRKKNFERSLPLLQVMGAN 649
MAG ++ + + +L+ + +N
Sbjct: 137 MAGGTAQDVKDAHAVLRHVASN 158
Score = 35.5 bits (78), Expect = 1.8
Identities = 18/47 (38%), Positives = 24/47 (51%)
Frame = +1
Query: 187 VAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGVTPANS 327
VA +G G MGG + A LV+ G + +DP D + A G A S
Sbjct: 5 VALIGAGAMGGSIGARLVETGNRLTVFDPGPDKVQALVDKGAFAAPS 51
>UniRef50_Q6UCZ9 Cluster: Predicted oxidoreductase; n=2;
environmental samples|Rep: Predicted oxidoreductase -
uncultured marine proteobacterium ANT32C12
Length = 309
Score = 52.0 bits (119), Expect = 2e-05
Identities = 24/75 (32%), Positives = 42/75 (56%)
Frame = +2
Query: 407 GKDGVVAHAKKGSLLIDSSTIDXNVPQQIFPIALEKGLGFTDAPVSGRVMGCSKRYLAFM 586
GK G++ G+++ID +T + +++ +AL+K + F DAP+SG G L+ M
Sbjct: 97 GKKGILNSVNPGTIIIDHTTTSATLSKEMNELALQKDVIFLDAPISGGQAGAESGQLSVM 156
Query: 587 AGXRKKNFERSLPLL 631
G K ++E P+L
Sbjct: 157 VGGDKASYESVKPIL 171
>UniRef50_Q1V2R0 Cluster: MmsB-like protein; n=2; Candidatus
Pelagibacter ubique|Rep: MmsB-like protein - Candidatus
Pelagibacter ubique HTCC1002
Length = 308
Score = 52.0 bits (119), Expect = 2e-05
Identities = 26/77 (33%), Positives = 42/77 (54%)
Frame = +1
Query: 184 NVAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGVTPANSIXXXXXXXXXXX 363
++AF+G+GNMG MA LVK G V+ +D S + + A ++G+ ++I
Sbjct: 4 HIAFIGVGNMGNPMADQLVKAGKEVKAFDVSPEVIKIAKESGLNVVSTIDELLDGASTVI 63
Query: 364 SILTSNKVVLDVYLGQR 414
S+L K V +YLG +
Sbjct: 64 SMLPEGKHVRSLYLGDK 80
Score = 48.0 bits (109), Expect = 3e-04
Identities = 29/90 (32%), Positives = 42/90 (46%)
Frame = +2
Query: 407 GKDGVVAHAKKGSLLIDSSTIDXNVPQQIFPIALEKGLGFTDAPVSGRVMGCSKRYLAFM 586
G G++ K L+ID STID ++ + + G+ DAPV+G VMG L F+
Sbjct: 78 GDKGILNKIPKECLIIDCSTIDIETSLELGNESKKLGIKMIDAPVTGGVMGARIGKLNFL 137
Query: 587 AGXRKKNFERSLPLLQVMGANSXTADRSGS 676
G + + PL +MG A GS
Sbjct: 138 VGGSDEAVALAKPLFDIMGQKILHAGVQGS 167
>UniRef50_Q0S5S3 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=1;
Rhodococcus sp. RHA1|Rep: 3-hydroxyisobutyrate
dehydrogenase - Rhodococcus sp. (strain RHA1)
Length = 299
Score = 52.0 bits (119), Expect = 2e-05
Identities = 28/86 (32%), Positives = 44/86 (51%)
Frame = +2
Query: 419 VVAHAKKGSLLIDSSTIDXNVPQQIFPIALEKGLGFTDAPVSGRVMGCSKRYLAFMAGXR 598
V+ +G +++D STID + +++ A G F DAPVSG V G LA M G
Sbjct: 79 VLQQGNQGLVIVDHSTIDPDTTRRLAQDAQVAGACFLDAPVSGGVQGAEAGTLAVMLGGD 138
Query: 599 KKNFERSLPLLQVMGANSXTADRSGS 676
+ + ++ +PL++ N SGS
Sbjct: 139 EASVKKVIPLIETYAGNIFHVGPSGS 164
Score = 39.9 bits (89), Expect = 0.082
Identities = 20/41 (48%), Positives = 27/41 (65%)
Frame = +1
Query: 187 VAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNG 309
V F+GLGN+GG + A+LVK G V YD + A++AA G
Sbjct: 5 VGFVGLGNIGGRVVAHLVKAGHDVAVYDLNTAAVDAAVALG 45
>UniRef50_Q0RCX7 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=1;
Frankia alni ACN14a|Rep: 3-hydroxyisobutyrate
dehydrogenase - Frankia alni (strain ACN14a)
Length = 313
Score = 52.0 bits (119), Expect = 2e-05
Identities = 28/80 (35%), Positives = 38/80 (47%)
Frame = +2
Query: 407 GKDGVVAHAKKGSLLIDSSTIDXNVPQQIFPIALEKGLGFTDAPVSGRVMGCSKRYLAFM 586
G DG + G+ ++D +T + +I A E G+GF DAPVSG G L+ M
Sbjct: 77 GPDGALGALAPGATIVDHTTTSAELAVEIAARAAEVGVGFVDAPVSGGQAGAEAGRLSVM 136
Query: 587 AGXRKKNFERSLPLLQVMGA 646
G ER P+L GA
Sbjct: 137 CGGEVDTVERVRPVLAAYGA 156
>UniRef50_A6SUL3 Cluster: 2-hydroxy-3-oxopropionate reductase; n=1;
Janthinobacterium sp. Marseille|Rep:
2-hydroxy-3-oxopropionate reductase - Janthinobacterium
sp. (strain Marseille) (Minibacterium massiliensis)
Length = 304
Score = 51.6 bits (118), Expect = 3e-05
Identities = 28/77 (36%), Positives = 42/77 (54%)
Frame = +2
Query: 413 DGVVAHAKKGSLLIDSSTIDXNVPQQIFPIALEKGLGFTDAPVSGRVMGCSKRYLAFMAG 592
D + K G+L+ID S+ + Q++ +G+ F DAPVSG V+G LA MAG
Sbjct: 82 DAALPGLKHGALVIDMSSTRQSEAQEVHAKLAAQGVRFIDAPVSGGVVGAEAGSLAIMAG 141
Query: 593 XRKKNFERSLPLLQVMG 643
++F + +L VMG
Sbjct: 142 GSAQDFAEAEAVLTVMG 158
Score = 34.3 bits (75), Expect = 4.1
Identities = 18/71 (25%), Positives = 35/71 (49%)
Frame = +1
Query: 187 VAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGVTPANSIXXXXXXXXXXXS 366
+AFLG+G MG MA+ L++ G+ V ++ ++ + A G + A + +
Sbjct: 10 IAFLGIGLMGKPMASRLLQAGYPVTAWNRTRSKADELAPLGASVAERVADAVAAADIVIT 69
Query: 367 ILTSNKVVLDV 399
+L + +V V
Sbjct: 70 MLEAGPIVAQV 80
>UniRef50_A6LT11 Cluster: 6-phosphogluconate dehydrogenase,
NAD-binding; n=3; Clostridiales|Rep: 6-phosphogluconate
dehydrogenase, NAD-binding - Clostridium beijerinckii
NCIMB 8052
Length = 291
Score = 51.6 bits (118), Expect = 3e-05
Identities = 27/91 (29%), Positives = 50/91 (54%)
Frame = +2
Query: 404 WGKDGVVAHAKKGSLLIDSSTIDXNVPQQIFPIALEKGLGFTDAPVSGRVMGCSKRYLAF 583
+G++G++ +AKK S +ID +T + +I+ A ++ + DAPVSG +G L+
Sbjct: 76 FGENGILENAKKESCIIDMTTTSPKLSIKIYNEAKKREIYALDAPVSGGDVGAKNATLSI 135
Query: 584 MAGXRKKNFERSLPLLQVMGANSXTADRSGS 676
M G + FE+ +L +G N ++G+
Sbjct: 136 MVGGDLEVFEKHKDVLSALGTNIIYEGKAGN 166
Score = 39.9 bits (89), Expect = 0.082
Identities = 22/77 (28%), Positives = 36/77 (46%)
Frame = +1
Query: 181 KNVAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGVTPANSIXXXXXXXXXX 360
K + F+G+G MG M NL+KKG+ V Y +K+ + G + +
Sbjct: 2 KTIGFIGVGVMGKSMVRNLMKKGYEVSIYTRTKEKVLDVINEGAKWCDDVKSCANNRDVI 61
Query: 361 XSILTSNKVVLDVYLGQ 411
+I+ K V +VY G+
Sbjct: 62 ITIVGYPKDVEEVYFGE 78
>UniRef50_Q4KH51 Cluster: 3-hydroxyisobutyrate dehydrogenase family
protein; n=16; Gammaproteobacteria|Rep:
3-hydroxyisobutyrate dehydrogenase family protein -
Pseudomonas fluorescens (strain Pf-5 / ATCC BAA-477)
Length = 298
Score = 51.2 bits (117), Expect = 3e-05
Identities = 26/81 (32%), Positives = 43/81 (53%), Gaps = 1/81 (1%)
Frame = +2
Query: 404 WGKDGVVAHAKKGSLLIDSSTIDXNVPQQIFP-IALEKGLGFTDAPVSGRVMGCSKRYLA 580
+G G+ A+ G LL+D S+++ +++ +A +G+ + DAPVSG G LA
Sbjct: 80 FGPQGIAQGARAGQLLLDLSSLEPTATREMAAELAASRGVAWVDAPVSGGTPGAEAGSLA 139
Query: 581 FMAGXRKKNFERSLPLLQVMG 643
M G + ER P+L +G
Sbjct: 140 IMVGGEATDVERVRPVLLTLG 160
>UniRef50_A3EW86 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=1;
Leptospirillum sp. Group II UBA|Rep:
3-hydroxyisobutyrate dehydrogenase - Leptospirillum sp.
Group II UBA
Length = 279
Score = 51.2 bits (117), Expect = 3e-05
Identities = 29/79 (36%), Positives = 40/79 (50%)
Frame = +2
Query: 407 GKDGVVAHAKKGSLLIDSSTIDXNVPQQIFPIALEKGLGFTDAPVSGRVMGCSKRYLAFM 586
G DG+ + GSL+I+ STI Q+ L KG G+ D PVSG ++ K L +
Sbjct: 64 GPDGIARGLRPGSLVINMSTIAPEEAQEEALSLLAKGAGYLDVPVSGSLVPAEKGELLLL 123
Query: 587 AGXRKKNFERSLPLLQVMG 643
AG ER+ P+L G
Sbjct: 124 AGGDGAALERARPILLHFG 142
>UniRef50_Q11FC5 Cluster: 6-phosphogluconate dehydrogenase,
NAD-binding; n=2; Rhizobiales|Rep: 6-phosphogluconate
dehydrogenase, NAD-binding - Mesorhizobium sp. (strain
BNC1)
Length = 292
Score = 50.8 bits (116), Expect = 4e-05
Identities = 31/93 (33%), Positives = 45/93 (48%)
Frame = +2
Query: 407 GKDGVVAHAKKGSLLIDSSTIDXNVPQQIFPIALEKGLGFTDAPVSGRVMGCSKRYLAFM 586
G+DG+ G+L+ID STI + + I +G+ DAPVSG V G L+ M
Sbjct: 77 GEDGIGTLLPTGTLVIDMSTISASGIRAIGQDLASRGVDLVDAPVSGGVRGAIAGELSIM 136
Query: 587 AGXRKKNFERSLPLLQVMGANSXTADRSGSXXV 685
G + F ++ P+L+ MG A G V
Sbjct: 137 CGGSPEAFAKARPVLEGMGTTIIHAGDLGMGQV 169
Score = 47.6 bits (108), Expect = 4e-04
Identities = 28/75 (37%), Positives = 38/75 (50%)
Frame = +1
Query: 187 VAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGVTPANSIXXXXXXXXXXXS 366
+AF+G G MG M ANL K GF ++ YD S AL +GVT A+S+ +
Sbjct: 4 LAFIGAGVMGRPMIANLRKAGFALKAYDRSPAALENLRSDGVTVADSLAAAVAGADVVVT 63
Query: 367 ILTSNKVVLDVYLGQ 411
+L V V LG+
Sbjct: 64 MLPDTPHVQSVLLGE 78
>UniRef50_A6G049 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=1;
Plesiocystis pacifica SIR-1|Rep: 3-hydroxyisobutyrate
dehydrogenase - Plesiocystis pacifica SIR-1
Length = 307
Score = 50.8 bits (116), Expect = 4e-05
Identities = 23/82 (28%), Positives = 43/82 (52%)
Frame = +2
Query: 407 GKDGVVAHAKKGSLLIDSSTIDXNVPQQIFPIALEKGLGFTDAPVSGRVMGCSKRYLAFM 586
G+ G +A +G+L+ID T + +Q+ +G F DAP++G +G L M
Sbjct: 88 GEGGALAGVGQGALVIDCGTTSLKLTEQLAAACEGEGASFLDAPITGSKLGAEGGKLTIM 147
Query: 587 AGXRKKNFERSLPLLQVMGANS 652
++ R++PL ++MG ++
Sbjct: 148 VAGEEEIVARAMPLFEIMGKHT 169
Score = 34.7 bits (76), Expect = 3.1
Identities = 17/38 (44%), Positives = 21/38 (55%)
Frame = +1
Query: 187 VAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAA 300
+AFLG G MG M NL G +R Y+ +K AAA
Sbjct: 4 IAFLGTGTMGAGMVRNLAAAGHELRIYNRTKSRAEAAA 41
>UniRef50_A1B741 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=3;
Bacteria|Rep: 3-hydroxyisobutyrate dehydrogenase -
Paracoccus denitrificans (strain Pd 1222)
Length = 309
Score = 50.8 bits (116), Expect = 4e-05
Identities = 28/79 (35%), Positives = 42/79 (53%)
Frame = +2
Query: 404 WGKDGVVAHAKKGSLLIDSSTIDXNVPQQIFPIALEKGLGFTDAPVSGRVMGCSKRYLAF 583
+G G+V G++ +D ST +V +QI KG+ F DAPVSG G + LA
Sbjct: 75 FGPRGLVEGMAPGTVWLDLSTNSVDVVRQIHAELAPKGIHFIDAPVSGGPAGAASGQLAI 134
Query: 584 MAGXRKKNFERSLPLLQVM 640
G ++ ++R LP L+ M
Sbjct: 135 WCGGEREVYDRCLPWLEKM 153
>UniRef50_A0LTQ8 Cluster: 6-phosphogluconate dehydrogenase,
NAD-binding precursor; n=1; Acidothermus cellulolyticus
11B|Rep: 6-phosphogluconate dehydrogenase, NAD-binding
precursor - Acidothermus cellulolyticus (strain ATCC
43068 / 11B)
Length = 305
Score = 50.8 bits (116), Expect = 4e-05
Identities = 27/79 (34%), Positives = 40/79 (50%)
Frame = +2
Query: 407 GKDGVVAHAKKGSLLIDSSTIDXNVPQQIFPIALEKGLGFTDAPVSGRVMGCSKRYLAFM 586
G DGVVA A+ G ++ + ST++ V + I P KG D PVSG V + L M
Sbjct: 78 GPDGVVAGARPGLVVAELSTVEPEVARAIAPELRAKGADILDVPVSGSVAVAREGGLTLM 137
Query: 587 AGXRKKNFERSLPLLQVMG 643
G + + P+L ++G
Sbjct: 138 VGGEDASLDAIRPVLDIIG 156
>UniRef50_A0GVR3 Cluster: 6-phosphogluconate dehydrogenase,
NAD-binding; n=1; Burkholderia phytofirmans PsJN|Rep:
6-phosphogluconate dehydrogenase, NAD-binding -
Burkholderia phytofirmans PsJN
Length = 311
Score = 50.4 bits (115), Expect = 6e-05
Identities = 28/90 (31%), Positives = 45/90 (50%)
Frame = +2
Query: 407 GKDGVVAHAKKGSLLIDSSTIDXNVPQQIFPIALEKGLGFTDAPVSGRVMGCSKRYLAFM 586
G G+ + +LL++ ST+D +++ A G DAP++G + G + L FM
Sbjct: 76 GAGGLFSITPPETLLLECSTVDVKTIERLGEGARASGTQLIDAPLTGGIEGAALATLTFM 135
Query: 587 AGXRKKNFERSLPLLQVMGANSXTADRSGS 676
G ++ E + P LQ MG+ A R GS
Sbjct: 136 VGGSEEQLEYARPALQSMGSRIVHAGRFGS 165
Score = 38.3 bits (85), Expect = 0.25
Identities = 23/74 (31%), Positives = 35/74 (47%)
Frame = +1
Query: 187 VAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGVTPANSIXXXXXXXXXXXS 366
+ F+G G MG M +NL+K V D ++DA + A G T A ++ +
Sbjct: 3 IGFIGAGRMGHRMISNLLKGSHAVLVLDGARDARDRVASLGATLAMNLADLVTGQDIVIT 62
Query: 367 ILTSNKVVLDVYLG 408
+L + V L VY G
Sbjct: 63 MLPTPDVSLSVYEG 76
>UniRef50_Q9V8M5-2 Cluster: Isoform C of Q9V8M5 ; n=1; Drosophila
melanogaster|Rep: Isoform C of Q9V8M5 - Drosophila
melanogaster (Fruit fly)
Length = 227
Score = 49.6 bits (113), Expect = 1e-04
Identities = 24/57 (42%), Positives = 32/57 (56%)
Frame = +1
Query: 145 TAARRAYSSNTDKNVAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGVT 315
T R + KN+ F+GLGNMG MA+NL+K G + +D SK A + A G T
Sbjct: 17 TLVRAMSTQGGAKNIGFVGLGNMGANMASNLIKAGHKLHVFDISKPACDGLAAKGAT 73
>UniRef50_A0C2T7 Cluster: Chromosome undetermined scaffold_145,
whole genome shotgun sequence; n=2; Paramecium
tetraurelia|Rep: Chromosome undetermined scaffold_145,
whole genome shotgun sequence - Paramecium tetraurelia
Length = 299
Score = 49.6 bits (113), Expect = 1e-04
Identities = 27/84 (32%), Positives = 41/84 (48%)
Frame = +2
Query: 434 KKGSLLIDSSTIDXNVPQQIFPIALEKGLGFTDAPVSGRVMGCSKRYLAFMAGXRKKNFE 613
K +LIDSSTI ++ +A + + DAPVSG V + FM G K+ +E
Sbjct: 90 KSKKILIDSSTISPYTSYELAKMAQDTQNIYADAPVSGSVSEAKLGTITFMVGAEKELYE 149
Query: 614 RSLPLLQVMGANSXTADRSGSXXV 685
+ P+L+ MG N + G +
Sbjct: 150 KISPILKEMGKNIFNCGKIGEGQI 173
Score = 36.3 bits (80), Expect = 1.0
Identities = 22/71 (30%), Positives = 33/71 (46%)
Frame = +1
Query: 187 VAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGVTPANSIXXXXXXXXXXXS 366
+ F+GLGNMG MA NL K V YD S + + + P N + +
Sbjct: 14 IGFIGLGNMGIGMAHNLAKTR-VVYAYDVSPAWQSNIESSNIKPVNQVADVAANADTIIT 72
Query: 367 ILTSNKVVLDV 399
+L ++K+V V
Sbjct: 73 MLPNDKIVKSV 83
>UniRef50_Q9V8M5 Cluster: Probable 3-hydroxyisobutyrate
dehydrogenase, mitochondrial precursor; n=4;
Diptera|Rep: Probable 3-hydroxyisobutyrate
dehydrogenase, mitochondrial precursor - Drosophila
melanogaster (Fruit fly)
Length = 324
Score = 49.6 bits (113), Expect = 1e-04
Identities = 24/57 (42%), Positives = 32/57 (56%)
Frame = +1
Query: 145 TAARRAYSSNTDKNVAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGVT 315
T R + KN+ F+GLGNMG MA+NL+K G + +D SK A + A G T
Sbjct: 17 TLVRAMSTQGGAKNIGFVGLGNMGANMASNLIKAGHKLHVFDISKPACDGLAAKGAT 73
Score = 46.8 bits (106), Expect = 7e-04
Identities = 25/69 (36%), Positives = 36/69 (52%)
Frame = +2
Query: 437 KGSLLIDSSTIDXNVPQQIFPIALEKGLGFTDAPVSGRVMGCSKRYLAFMAGXRKKNFER 616
K ++ IDSSTI ++ + + KG F DAPVSG V G + L FM G + +
Sbjct: 112 KDTIFIDSSTISPDLVKSLQKKISAKGARFIDAPVSGGVPGAEQATLTFMVGGTEAEYNA 171
Query: 617 SLPLLQVMG 643
+L+ MG
Sbjct: 172 VKAVLECMG 180
>UniRef50_Q47AR2 Cluster: NADP oxidoreductase, coenzyme
F420-dependent:6-phosphogluconate dehydrogenase,
NAD-binding; n=1; Dechloromonas aromatica RCB|Rep: NADP
oxidoreductase, coenzyme
F420-dependent:6-phosphogluconate dehydrogenase,
NAD-binding - Dechloromonas aromatica (strain RCB)
Length = 287
Score = 49.2 bits (112), Expect = 1e-04
Identities = 29/90 (32%), Positives = 42/90 (46%)
Frame = +2
Query: 416 GVVAHAKKGSLLIDSSTIDXNVPQQIFPIALEKGLGFTDAPVSGRVMGCSKRYLAFMAGX 595
GV + + G + +D STI ++I G+ F DAPVSG +G L+ MAG
Sbjct: 76 GVASAGESGLVAVDMSTIAPAAARRIGEDLAAAGIDFIDAPVSGGEVGAIAGSLSIMAGG 135
Query: 596 RKKNFERSLPLLQVMGANSXTADRSGSXXV 685
F ++ P + MG N SG+ V
Sbjct: 136 SDAAFAKAKPAFECMGKNIVHVGASGAGQV 165
Score = 34.3 bits (75), Expect = 4.1
Identities = 20/51 (39%), Positives = 28/51 (54%), Gaps = 4/51 (7%)
Frame = +1
Query: 187 VAFLGLGNMGGFMAANLVKKGFTV----RGYDPSKDALNAAAKNGVTPANS 327
+ F+GLG MG MA NL+K G V R + + L+A AK +PA +
Sbjct: 3 IGFIGLGIMGRPMALNLIKGGHQVTVWARRAESMQPLLDAGAKGAASPAEA 53
>UniRef50_Q1B326 Cluster: 6-phosphogluconate dehydrogenase,
NAD-binding protein precursor; n=7; Bacteria|Rep:
6-phosphogluconate dehydrogenase, NAD-binding protein
precursor - Mycobacterium sp. (strain MCS)
Length = 299
Score = 49.2 bits (112), Expect = 1e-04
Identities = 21/52 (40%), Positives = 33/52 (63%)
Frame = +1
Query: 175 TDKNVAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGVTPANSI 330
++ ++ F+GLGNMG MAANL+ G V Y+ S D ++A + G PA ++
Sbjct: 2 SNMHIGFIGLGNMGSAMAANLLAAGHDVTAYNRSPDKVDALSAEGARPARTV 53
Score = 40.3 bits (90), Expect = 0.062
Identities = 22/81 (27%), Positives = 38/81 (46%)
Frame = +2
Query: 401 TWGKDGVVAHAKKGSLLIDSSTIDXNVPQQIFPIALEKGLGFTDAPVSGRVMGCSKRYLA 580
++G DG+VA + ++ + SSTI + +++ E G F APV GR + L
Sbjct: 76 SFGDDGIVASLRPDAIHVSSSTISLALAERLTAAHAEGGSRFVSAPVFGRPEAAAAAKLF 135
Query: 581 FMAGXRKKNFERSLPLLQVMG 643
+A E P+ + +G
Sbjct: 136 VVAAGAPDTVEALAPVFEAIG 156
>UniRef50_Q9L7S0 Cluster: Uncharacterized oxidoreductase yihU; n=24;
Gammaproteobacteria|Rep: Uncharacterized oxidoreductase
yihU - Salmonella typhimurium
Length = 298
Score = 49.2 bits (112), Expect = 1e-04
Identities = 25/79 (31%), Positives = 41/79 (51%)
Frame = +1
Query: 187 VAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGVTPANSIXXXXXXXXXXXS 366
+AF+GLG MG MA+NL+K+G + +D + DA+ G PA+S +
Sbjct: 4 IAFIGLGQMGSPMASNLLKQGHQLSVFDVNPDAVQRLVDKGAQPASSPAQATIGAEFVIT 63
Query: 367 ILTSNKVVLDVYLGQRWRC 423
+L + +V V G++ C
Sbjct: 64 MLPNGDLVRSVLFGEQGVC 82
Score = 37.9 bits (84), Expect = 0.33
Identities = 22/80 (27%), Positives = 33/80 (41%)
Frame = +2
Query: 404 WGKDGVVAHAKKGSLLIDSSTIDXNVPQQIFPIALEKGLGFTDAPVSGRVMGCSKRYLAF 583
+G+ GV + +L+ID STI + KG D P+ L
Sbjct: 76 FGEQGVCETLSREALVIDMSTIHPLQTDNLIADMQSKGFSMMDVPIGRTSDNAITGTLLL 135
Query: 584 MAGXRKKNFERSLPLLQVMG 643
+AG + ER+ P+L MG
Sbjct: 136 LAGGTAEQVERATPVLMAMG 155
>UniRef50_Q5FQ06 Cluster: Putative oxidoreductase; n=1;
Gluconobacter oxydans|Rep: Putative oxidoreductase -
Gluconobacter oxydans (Gluconobacter suboxydans)
Length = 290
Score = 48.8 bits (111), Expect = 2e-04
Identities = 26/90 (28%), Positives = 45/90 (50%)
Frame = +2
Query: 407 GKDGVVAHAKKGSLLIDSSTIDXNVPQQIFPIALEKGLGFTDAPVSGRVMGCSKRYLAFM 586
G++G +A G L++D+ST+ + +A+E G DAP+SG L +
Sbjct: 73 GENGALAALTPGKLVLDTSTVSPDQADAFASLAVEHGFSLLDAPMSGSTPEAETGDLVML 132
Query: 587 AGXRKKNFERSLPLLQVMGANSXTADRSGS 676
G + +R+ P+L V+G + A +GS
Sbjct: 133 VGGDEAVVKRAQPVLDVIGKLTIHAGPAGS 162
>UniRef50_Q4ZQL5 Cluster: 3-hydroxyisobutyrate dehydrogenase
precursor; n=11; Proteobacteria|Rep:
3-hydroxyisobutyrate dehydrogenase precursor -
Pseudomonas syringae pv. syringae (strain B728a)
Length = 296
Score = 48.8 bits (111), Expect = 2e-04
Identities = 24/41 (58%), Positives = 27/41 (65%)
Frame = +1
Query: 196 LGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGVTP 318
+GLGNMGG MAA L KGF V G+D S+ AL A GV P
Sbjct: 8 IGLGNMGGGMAATLAGKGFDVSGFDLSQAALAQAESKGVKP 48
Score = 46.8 bits (106), Expect = 7e-04
Identities = 24/98 (24%), Positives = 48/98 (48%)
Frame = +2
Query: 392 STCTWGKDGVVAHAKKGSLLIDSSTIDXNVPQQIFPIALEKGLGFTDAPVSGRVMGCSKR 571
S C G G+ +KG +++D++T + +++ + G+ F DAPVSG G +
Sbjct: 74 SVCL-GAGGINEVGRKGLIVVDTTTSTPEMSRKVAAELAKNGIAFIDAPVSGGPKGAATG 132
Query: 572 YLAFMAGXRKKNFERSLPLLQVMGANSXTADRSGSXXV 685
++ + G + R++P+L+ M + G+ V
Sbjct: 133 SMSMVIGAEDADLARAMPVLEGMSGTRVHVGQCGAGNV 170
>UniRef50_A1UP64 Cluster: 6-phosphogluconate dehydrogenase,
NAD-binding; n=3; Mycobacterium|Rep: 6-phosphogluconate
dehydrogenase, NAD-binding - Mycobacterium sp. (strain
KMS)
Length = 305
Score = 48.8 bits (111), Expect = 2e-04
Identities = 30/83 (36%), Positives = 39/83 (46%)
Frame = +2
Query: 404 WGKDGVVAHAKKGSLLIDSSTIDXNVPQQIFPIALEKGLGFTDAPVSGRVMGCSKRYLAF 583
+G GV + GSL+ID STI + I EK + F DAPVSG G LA
Sbjct: 75 FGPAGVTTTLRPGSLVIDCSTISPDAAVAIGARLAEKDIAFVDAPVSGGEAGAIAGALAV 134
Query: 584 MAGXRKKNFERSLPLLQVMGANS 652
M G + R+ +L + A S
Sbjct: 135 MMGGDEDAVRRAATVLDAVAATS 157
>UniRef50_Q8KL12 Cluster: Probable 6-phosphogluconate dehydrogenase
protein; n=1; Rhizobium etli CFN 42|Rep: Probable
6-phosphogluconate dehydrogenase protein - Rhizobium
etli (strain CFN 42 / ATCC 51251)
Length = 294
Score = 48.4 bits (110), Expect = 2e-04
Identities = 35/117 (29%), Positives = 56/117 (47%)
Frame = +1
Query: 166 SSNTDKNVAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGVTPANSIXXXXX 345
S + VAF+GLG MGG MA +L+ F V G+D S +A A G PA ++
Sbjct: 2 SPRKNLRVAFIGLGAMGGPMAQHLLSAQFEVTGFDLSAEARERFAAVGGVPAETVAEAFN 61
Query: 346 XXXXXXSILTSNKVVLDVYLGQRWRCGSCEKRIASDRFEYDRXECSPTDLSYSLRER 516
++L + K+V D ++ G+ + +++D D +P D + L ER
Sbjct: 62 GADVAVTMLPNGKIVQDAL----FKDGAWQS-LSADALVIDMSSSAPND-TRELAER 112
Score = 44.4 bits (100), Expect = 0.004
Identities = 28/89 (31%), Positives = 41/89 (46%)
Frame = +2
Query: 410 KDGVVAHAKKGSLLIDSSTIDXNVPQQIFPIALEKGLGFTDAPVSGRVMGCSKRYLAFMA 589
KDG +L+ID S+ N +++ +KGL DAPVSG V + L MA
Sbjct: 82 KDGAWQSLSADALVIDMSSSAPNDTRELAERLHQKGLRLVDAPVSGGVKRAVEGSLTIMA 141
Query: 590 GXRKKNFERSLPLLQVMGANSXTADRSGS 676
G + +++ P+L MG GS
Sbjct: 142 GGASDDIDQADPILCAMGGQIFRTGPIGS 170
>UniRef50_Q606G9 Cluster: Oxidoreductase, Gfo/Idh/MocA family; n=6;
Proteobacteria|Rep: Oxidoreductase, Gfo/Idh/MocA family
- Methylococcus capsulatus
Length = 289
Score = 48.4 bits (110), Expect = 2e-04
Identities = 24/71 (33%), Positives = 38/71 (53%)
Frame = +2
Query: 434 KKGSLLIDSSTIDXNVPQQIFPIALEKGLGFTDAPVSGRVMGCSKRYLAFMAGXRKKNFE 613
+ G++++D ST+ ++ + + G F DAPVSG V G LA M G R + E
Sbjct: 83 RPGAVIVDCSTVGVATARRAAEVVRQAGGDFLDAPVSGGVEGARDGTLALMIGGRAETVE 142
Query: 614 RSLPLLQVMGA 646
+ P+L MG+
Sbjct: 143 KVRPVLAAMGS 153
>UniRef50_A5USN9 Cluster: 6-phosphogluconate dehydrogenase,
NAD-binding; n=2; Roseiflexus|Rep: 6-phosphogluconate
dehydrogenase, NAD-binding - Roseiflexus sp. RS-1
Length = 302
Score = 48.4 bits (110), Expect = 2e-04
Identities = 26/79 (32%), Positives = 41/79 (51%)
Frame = +2
Query: 407 GKDGVVAHAKKGSLLIDSSTIDXNVPQQIFPIALEKGLGFTDAPVSGRVMGCSKRYLAFM 586
G+DG+++ G L I+ STI + + + ++G DAPVSG V + L +
Sbjct: 77 GRDGLLSTDASGRLFIEMSTIRTSTILSLAGMVDQRGARLLDAPVSGTVAPAREGQLLVL 136
Query: 587 AGXRKKNFERSLPLLQVMG 643
G R + ER+ P L V+G
Sbjct: 137 VGGRTSDLERARPALGVLG 155
Score = 35.9 bits (79), Expect = 1.3
Identities = 21/77 (27%), Positives = 34/77 (44%)
Frame = +1
Query: 181 KNVAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGVTPANSIXXXXXXXXXX 360
+ + F+GLG MG MA L+ GF + ++ ++ A G A +
Sbjct: 2 ERLGFIGLGRMGQVMAGRLLAAGFPLTVHNRTRARAEALLAGGAAWAETPAEVTARSDLV 61
Query: 361 XSILTSNKVVLDVYLGQ 411
+ILT + V VY G+
Sbjct: 62 FTILTDDHAVETVYCGR 78
>UniRef50_Q3DYV4 Cluster: NADP oxidoreductase, coenzyme
F420-dependent:6-phosphogluconate dehydrogenase,
NAD-binding; n=2; Chloroflexus|Rep: NADP oxidoreductase,
coenzyme F420-dependent:6-phosphogluconate
dehydrogenase, NAD-binding - Chloroflexus aurantiacus
J-10-fl
Length = 289
Score = 48.0 bits (109), Expect = 3e-04
Identities = 24/70 (34%), Positives = 37/70 (52%)
Frame = +2
Query: 434 KKGSLLIDSSTIDXNVPQQIFPIALEKGLGFTDAPVSGRVMGCSKRYLAFMAGXRKKNFE 613
++G L+ID + D Q +G+G+ DAPVSG G + LA M G + E
Sbjct: 79 REGQLIIDMGSSDPRHSQTHATTLANRGIGWVDAPVSGGPEGAAAGTLAIMVGGTASDVE 138
Query: 614 RSLPLLQVMG 643
R+ P+L+ +G
Sbjct: 139 RAEPILRALG 148
Score = 33.1 bits (72), Expect = 9.4
Identities = 18/48 (37%), Positives = 28/48 (58%)
Frame = +1
Query: 187 VAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGVTPANSI 330
+A +GLG MG MA L+K GF V G+ ++ L+ A G+ A ++
Sbjct: 3 IALIGLGLMGRPMARTLLKAGFNVTGW--NRSPLDPALTEGIPLAATL 48
>UniRef50_Q0LNZ7 Cluster: 3-hydroxyisobutyrate dehydrogenase
precursor; n=1; Herpetosiphon aurantiacus ATCC
23779|Rep: 3-hydroxyisobutyrate dehydrogenase precursor
- Herpetosiphon aurantiacus ATCC 23779
Length = 301
Score = 48.0 bits (109), Expect = 3e-04
Identities = 31/93 (33%), Positives = 39/93 (41%)
Frame = +2
Query: 407 GKDGVVAHAKKGSLLIDSSTIDXNVPQQIFPIALEKGLGFTDAPVSGRVMGCSKRYLAFM 586
G +G GS+ ID STI + I E+ + DAPVSG LA M
Sbjct: 80 GTNGAAYGMAAGSICIDMSTIAPTASRAIAAKLAERQIAMLDAPVSGGPARAKTGELAIM 139
Query: 587 AGXRKKNFERSLPLLQVMGANSXTADRSGSXXV 685
G FER +L+V+G SGS V
Sbjct: 140 VGGEPSTFERCQAVLEVLGGAVSYIGASGSGSV 172
>UniRef50_Q01QM2 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=1;
Solibacter usitatus Ellin6076|Rep: 3-hydroxyisobutyrate
dehydrogenase - Solibacter usitatus (strain Ellin6076)
Length = 298
Score = 48.0 bits (109), Expect = 3e-04
Identities = 26/79 (32%), Positives = 39/79 (49%)
Frame = +2
Query: 407 GKDGVVAHAKKGSLLIDSSTIDXNVPQQIFPIALEKGLGFTDAPVSGRVMGCSKRYLAFM 586
G G++ + G++++D STI ++I K + F DAPV+G G L FM
Sbjct: 78 GGQGLIQGLRAGAVVVDCSTIAVADSREIGAALKAKSVDFLDAPVTGSTPGAESGNLTFM 137
Query: 587 AGXRKKNFERSLPLLQVMG 643
G + F + PLL MG
Sbjct: 138 IGGDEAVFSKIRPLLDPMG 156
>UniRef50_A2SP40 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=1;
Methylibium petroleiphilum PM1|Rep: 3-hydroxyisobutyrate
dehydrogenase - Methylibium petroleiphilum (strain PM1)
Length = 297
Score = 48.0 bits (109), Expect = 3e-04
Identities = 27/78 (34%), Positives = 40/78 (51%)
Frame = +1
Query: 181 KNVAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGVTPANSIXXXXXXXXXX 360
K + +GLGN+GG M L+ +G V G+D S A AAA++G S
Sbjct: 2 KEIGLIGLGNIGGGMCRRLLDRGIGVVGFDLSPAATKAAAEHGARIEVSPAAVAQQVDVV 61
Query: 361 XSILTSNKVVLDVYLGQR 414
+ L + +V DVYLG++
Sbjct: 62 VTSLPNPPIVRDVYLGKQ 79
>UniRef50_P77161 Cluster: 2-hydroxy-3-oxopropionate reductase; n=99;
Proteobacteria|Rep: 2-hydroxy-3-oxopropionate reductase
- Escherichia coli (strain K12)
Length = 292
Score = 48.0 bits (109), Expect = 3e-04
Identities = 26/82 (31%), Positives = 43/82 (52%)
Frame = +2
Query: 404 WGKDGVVAHAKKGSLLIDSSTIDXNVPQQIFPIALEKGLGFTDAPVSGRVMGCSKRYLAF 583
+G++G + KG ++D S+I ++ E G + DAPVSG +G + L+
Sbjct: 74 FGENGCTKASLKGKTIVDMSSISPIETKRFARQVNELGGDYLDAPVSGGEIGAREGTLSI 133
Query: 584 MAGXRKKNFERSLPLLQVMGAN 649
M G + FER PL +++G N
Sbjct: 134 MVGGDEAVFERVKPLFELLGKN 155
>UniRef50_A5P0V0 Cluster: 6-phosphogluconate dehydrogenase,
NAD-binding precursor; n=3; Rhizobiales|Rep:
6-phosphogluconate dehydrogenase, NAD-binding precursor
- Methylobacterium sp. 4-46
Length = 299
Score = 47.6 bits (108), Expect = 4e-04
Identities = 25/48 (52%), Positives = 32/48 (66%)
Frame = +1
Query: 187 VAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGVTPANSI 330
VAF+GLG MG MA NLV KGF VRGYD ++ A A+ G A+++
Sbjct: 6 VAFVGLGAMGLPMAQNLVAKGFPVRGYDVRPESRAALARAGGEAADTL 53
Score = 33.9 bits (74), Expect = 5.4
Identities = 19/44 (43%), Positives = 22/44 (50%)
Frame = +2
Query: 515 GLGFTDAPVSGRVMGCSKRYLAFMAGXRKKNFERSLPLLQVMGA 646
G F DAPVSG V+G L MA + F PLL +GA
Sbjct: 119 GRRFVDAPVSGGVVGAEAGSLTVMAAAPAEVFGAVRPLLDAVGA 162
>UniRef50_A1R2J4 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=1;
Arthrobacter aurescens TC1|Rep: 3-hydroxyisobutyrate
dehydrogenase - Arthrobacter aurescens (strain TC1)
Length = 332
Score = 47.2 bits (107), Expect = 5e-04
Identities = 26/90 (28%), Positives = 38/90 (42%)
Frame = +2
Query: 374 PAIKSCSTCTWGKDGVVAHAKKGSLLIDSSTIDXNVPQQIFPIALEKGLGFTDAPVSGRV 553
P K T G G++A G +D ST V ++ +G+ DAPVSG
Sbjct: 88 PTPKHVETVAMGPGGILAGMPDGGTWVDMSTSVPEVANRVREAGSVRGIRVLDAPVSGMS 147
Query: 554 MGCSKRYLAFMAGXRKKNFERSLPLLQVMG 643
+G + L G + ER P+ + MG
Sbjct: 148 VGAANGMLQIFVGGEPADVERLRPVFEAMG 177
Score = 33.5 bits (73), Expect = 7.1
Identities = 22/74 (29%), Positives = 31/74 (41%)
Frame = +1
Query: 187 VAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGVTPANSIXXXXXXXXXXXS 366
+ F+GLGNMG M NL GF + D K++ NG A +
Sbjct: 26 IGFIGLGNMGSGMTRNLQAAGFHLVVNDVRKESAAELLANGAEWAEDAAAVAAGSDVVIT 85
Query: 367 ILTSNKVVLDVYLG 408
+L + K V V +G
Sbjct: 86 MLPTPKHVETVAMG 99
>UniRef50_A0G5F9 Cluster: 6-phosphogluconate dehydrogenase,
NAD-binding; n=2; Burkholderia|Rep: 6-phosphogluconate
dehydrogenase, NAD-binding - Burkholderia phymatum
STM815
Length = 307
Score = 47.2 bits (107), Expect = 5e-04
Identities = 28/87 (32%), Positives = 39/87 (44%)
Frame = +2
Query: 413 DGVVAHAKKGSLLIDSSTIDXNVPQQIFPIALEKGLGFTDAPVSGRVMGCSKRYLAFMAG 592
DG + +L+D ST+ V +++ L KG+ DAPVSG G K LA MA
Sbjct: 89 DGGLIEGSAIKVLVDLSTVGSRVEKEVAQGLLAKGVETVDAPVSGGAAGAKKGTLAIMAA 148
Query: 593 XRKKNFERSLPLLQVMGANSXTADRSG 673
E L V+G D++G
Sbjct: 149 GSPVALEEVRGLFDVLGKAFVVGDKAG 175
>UniRef50_P0ABQ3 Cluster: 2-hydroxy-3-oxopropionate reductase; n=25;
Bacteria|Rep: 2-hydroxy-3-oxopropionate reductase -
Escherichia coli O6
Length = 294
Score = 47.2 bits (107), Expect = 5e-04
Identities = 28/93 (30%), Positives = 45/93 (48%)
Frame = +2
Query: 407 GKDGVVAHAKKGSLLIDSSTIDXNVPQQIFPIALEKGLGFTDAPVSGRVMGCSKRYLAFM 586
G++G++ AK G++LID S+I ++I KG+ DAPVSG L+ M
Sbjct: 76 GENGIIEGAKPGTVLIDMSSIAPLASREISEALKAKGIDMLDAPVSGGEPKAIDGTLSVM 135
Query: 587 AGXRKKNFERSLPLLQVMGANSXTADRSGSXXV 685
G K F++ L++ M + G+ V
Sbjct: 136 VGGDKAIFDKYYDLMKAMAGSVVHTGEIGAGNV 168
>UniRef50_Q89R44 Cluster: Oxidoreductase; n=23; Bacteria|Rep:
Oxidoreductase - Bradyrhizobium japonicum
Length = 305
Score = 46.8 bits (106), Expect = 7e-04
Identities = 25/84 (29%), Positives = 41/84 (48%)
Frame = +2
Query: 395 TCTWGKDGVVAHAKKGSLLIDSSTIDXNVPQQIFPIALEKGLGFTDAPVSGRVMGCSKRY 574
T +GKDGV K S+ + S+T+D +V +++ G + DAP+SG ++
Sbjct: 80 TILFGKDGVAETMPKDSVFLSSATMDPDVARRLAKQLEATGRHYLDAPISGGAQRAAQGE 139
Query: 575 LAFMAGXRKKNFERSLPLLQVMGA 646
L +A F ++ P L M A
Sbjct: 140 LTILASGSPAAFAKARPALDAMAA 163
Score = 38.7 bits (86), Expect = 0.19
Identities = 19/48 (39%), Positives = 30/48 (62%)
Frame = +1
Query: 166 SSNTDKNVAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNG 309
S++ ++ +A +GLG+MG MA +L + G V G D S DA+ K+G
Sbjct: 4 STSQNQRIAVVGLGSMGFGMATSLKRAGHAVTGCDVSADAVARFVKDG 51
>UniRef50_A6EH53 Cluster: Putative uncharacterized protein; n=1;
Pedobacter sp. BAL39|Rep: Putative uncharacterized
protein - Pedobacter sp. BAL39
Length = 292
Score = 46.8 bits (106), Expect = 7e-04
Identities = 23/79 (29%), Positives = 40/79 (50%)
Frame = +2
Query: 407 GKDGVVAHAKKGSLLIDSSTIDXNVPQQIFPIALEKGLGFTDAPVSGRVMGCSKRYLAFM 586
G DG+++ G ++++ ST+ + ++ G+ + DAPVSG V + L M
Sbjct: 88 GADGLLSKELHGKVIVNMSTVSPAISIKMAAACSAVGIEYLDAPVSGSVKQATDGQLVIM 147
Query: 587 AGXRKKNFERSLPLLQVMG 643
G ++ F + PLL MG
Sbjct: 148 VGGEEQAFHAAEPLLSCMG 166
>UniRef50_A3WAC4 Cluster: Dehydrogenase; n=4; Bacteria|Rep:
Dehydrogenase - Erythrobacter sp. NAP1
Length = 301
Score = 46.8 bits (106), Expect = 7e-04
Identities = 25/91 (27%), Positives = 45/91 (49%)
Frame = +2
Query: 404 WGKDGVVAHAKKGSLLIDSSTIDXNVPQQIFPIALEKGLGFTDAPVSGRVMGCSKRYLAF 583
+G++GV+A K+G+ ID +++ + ++I GL DAPVSG G L+
Sbjct: 85 FGENGVLAAMKRGATFIDHTSVSPGLARRIADECERLGLHAVDAPVSGGQAGAENGKLSI 144
Query: 584 MAGXRKKNFERSLPLLQVMGANSXTADRSGS 676
M G ++ + P++Q A +G+
Sbjct: 145 MCGGSEEAMASAQPVMQAYAARIVHIGEAGA 175
Score = 35.1 bits (77), Expect = 2.3
Identities = 16/30 (53%), Positives = 20/30 (66%)
Frame = +1
Query: 181 KNVAFLGLGNMGGFMAANLVKKGFTVRGYD 270
K +AFLGLG MGG M +LV+ G GY+
Sbjct: 5 KRIAFLGLGVMGGPMWGHLVRAGHEATGYN 34
>UniRef50_A0NRG5 Cluster: 6-phosphogluconate dehydrogenase,
NAD-binding protein; n=1; Stappia aggregata IAM
12614|Rep: 6-phosphogluconate dehydrogenase, NAD-binding
protein - Stappia aggregata IAM 12614
Length = 291
Score = 46.8 bits (106), Expect = 7e-04
Identities = 25/97 (25%), Positives = 43/97 (44%)
Frame = +2
Query: 386 SCSTCTWGKDGVVAHAKKGSLLIDSSTIDXNVPQQIFPIALEKGLGFTDAPVSGRVMGCS 565
+ T +G DG+ + +L++ T+ + +++ A EKG F DAPVSG
Sbjct: 70 AAETVYFGPDGLFEASSGAQVLVEMGTLSVPMAERLARAAQEKGRRFVDAPVSGATQAAK 129
Query: 566 KRYLAFMAGXRKKNFERSLPLLQVMGANSXTADRSGS 676
L MAG + L V+G + ++G+
Sbjct: 130 DAKLLIMAGATASDAPELAALFDVLGRKTIWLGKAGA 166
>UniRef50_A3H9B3 Cluster: 6-phosphogluconate dehydrogenase,
NAD-binding; n=1; Caldivirga maquilingensis IC-167|Rep:
6-phosphogluconate dehydrogenase, NAD-binding -
Caldivirga maquilingensis IC-167
Length = 293
Score = 46.8 bits (106), Expect = 7e-04
Identities = 27/74 (36%), Positives = 37/74 (50%)
Frame = +1
Query: 187 VAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGVTPANSIXXXXXXXXXXXS 366
V +GLG MGG L+ KGF + YD +D +N K G T A+S +
Sbjct: 3 VGLVGLGRMGGAFGRVLLSKGFNLVVYDVVRDKVNEFVKLGATGASSPADLASRVDIVLT 62
Query: 367 ILTSNKVVLDVYLG 408
+ ++ VLDVYLG
Sbjct: 63 NVPRSEDVLDVYLG 76
>UniRef50_Q7WG50 Cluster: Probable oxidoreductase; n=1; Bordetella
bronchiseptica|Rep: Probable oxidoreductase - Bordetella
bronchiseptica (Alcaligenes bronchisepticus)
Length = 316
Score = 46.4 bits (105), Expect = 0.001
Identities = 24/41 (58%), Positives = 28/41 (68%)
Frame = +1
Query: 187 VAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNG 309
+AFLGLG MG MA NLVK G V GYD + AL+A A+ G
Sbjct: 6 IAFLGLGAMGLPMACNLVKGGHAVTGYDLNPQALDALAQAG 46
Score = 33.1 bits (72), Expect = 9.4
Identities = 22/79 (27%), Positives = 33/79 (41%)
Frame = +2
Query: 407 GKDGVVAHAKKGSLLIDSSTIDXNVPQQIFPIALEKGLGFTDAPVSGRVMGCSKRYLAFM 586
G DG + G+L I+ STI I E+G+ D+PV M + L +
Sbjct: 79 GADGALQGMDPGALFINMSTILPQETDLIAQRLAERGMRMLDSPVGRSAMEAQRGTLLIL 138
Query: 587 AGXRKKNFERSLPLLQVMG 643
A ++ R+ L MG
Sbjct: 139 ASGSAQDKARARDALLCMG 157
>UniRef50_A6SW62 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=1;
Janthinobacterium sp. Marseille|Rep:
3-hydroxyisobutyrate dehydrogenase - Janthinobacterium
sp. (strain Marseille) (Minibacterium massiliensis)
Length = 298
Score = 46.4 bits (105), Expect = 0.001
Identities = 26/74 (35%), Positives = 38/74 (51%), Gaps = 1/74 (1%)
Frame = +1
Query: 181 KNVAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNA-AAKNGVTPANSIXXXXXXXXX 357
+N+ F+G+GNMG MA L +KGF++ YD NA A ++G A S
Sbjct: 5 RNIGFIGIGNMGAPMAGQLARKGFSLTVYDTHATTANAFAQEHGARVARSAAEVGIGADA 64
Query: 358 XXSILTSNKVVLDV 399
+L S++VV V
Sbjct: 65 VIFMLPSDQVVRQV 78
Score = 43.2 bits (97), Expect = 0.009
Identities = 28/91 (30%), Positives = 35/91 (38%)
Frame = +2
Query: 413 DGVVAHAKKGSLLIDSSTIDXNVPQQIFPIALEKGLGFTDAPVSGRVMGCSKRYLAFMAG 592
DG+ GS+ ID T V + I G+G+ DAPV G V+ L M
Sbjct: 82 DGLATQLAPGSIAIDMGTSAPAVTRSISAELATLGIGYLDAPVMGGVVFAKDASLDIMVS 141
Query: 593 XRKKNFERSLPLLQVMGANSXTADRSGSXXV 685
+ ER PL MG GS V
Sbjct: 142 GDDASIERCRPLFDAMGRKLWPCGDIGSAHV 172
>UniRef50_A4SWE8 Cluster: 2-hydroxy-3-oxopropionate reductase
precursor; n=7; Proteobacteria|Rep:
2-hydroxy-3-oxopropionate reductase precursor -
Polynucleobacter sp. QLW-P1DMWA-1
Length = 299
Score = 46.4 bits (105), Expect = 0.001
Identities = 26/94 (27%), Positives = 42/94 (44%)
Frame = +2
Query: 404 WGKDGVVAHAKKGSLLIDSSTIDXNVPQQIFPIALEKGLGFTDAPVSGRVMGCSKRYLAF 583
+G+ GV KG +++D S+I + G + DAPVSG +G L
Sbjct: 77 FGEHGVAHGLSKGKIVVDMSSISPIATKDFAKKINALGCEYLDAPVSGGQVGAKGGTLTI 136
Query: 584 MAGXRKKNFERSLPLLQVMGANSXTADRSGSXXV 685
M G ++ F+ P+ +MG N +G+ V
Sbjct: 137 MVGGKESVFQTVKPMFDLMGKNITLVGDNGAGQV 170
>UniRef50_A3X9R7 Cluster: 3-hydroxyisobutyrate dehydrogenase family
protein; n=2; Rhodobacterales|Rep: 3-hydroxyisobutyrate
dehydrogenase family protein - Roseobacter sp. MED193
Length = 300
Score = 46.4 bits (105), Expect = 0.001
Identities = 22/71 (30%), Positives = 38/71 (53%)
Frame = +2
Query: 428 HAKKGSLLIDSSTIDXNVPQQIFPIALEKGLGFTDAPVSGRVMGCSKRYLAFMAGXRKKN 607
+ KKGS+++D+ST + + +++ A G F D PVSG +G + + G +
Sbjct: 93 YLKKGSIVVDTSTSEPDTTKRLAAAAESNGYTFLDGPVSGGPLGARTGTMTMVVGGDEAG 152
Query: 608 FERSLPLLQVM 640
F + PLL+ M
Sbjct: 153 FTKVRPLLEKM 163
>UniRef50_A0LDJ3 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=1;
Magnetococcus sp. MC-1|Rep: 3-hydroxyisobutyrate
dehydrogenase - Magnetococcus sp. (strain MC-1)
Length = 292
Score = 46.4 bits (105), Expect = 0.001
Identities = 27/80 (33%), Positives = 39/80 (48%)
Frame = +2
Query: 407 GKDGVVAHAKKGSLLIDSSTIDXNVPQQIFPIALEKGLGFTDAPVSGRVMGCSKRYLAFM 586
G GV + G ++I++ST+ QQ + + G F DAPVSG + L F+
Sbjct: 77 GPVGVCSADLTGKVVINASTVSVEASQQAATLVEQVGGAFLDAPVSGSKIPAQTGKLVFL 136
Query: 587 AGXRKKNFERSLPLLQVMGA 646
AG +R PLL MG+
Sbjct: 137 AGGHHAVIQRCEPLLLSMGS 156
>UniRef50_A0G5G5 Cluster: 6-phosphogluconate dehydrogenase,
NAD-binding; n=3; Proteobacteria|Rep: 6-phosphogluconate
dehydrogenase, NAD-binding - Burkholderia phymatum
STM815
Length = 306
Score = 46.4 bits (105), Expect = 0.001
Identities = 30/87 (34%), Positives = 39/87 (44%)
Frame = +1
Query: 181 KNVAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGVTPANSIXXXXXXXXXX 360
+ + F+GLGNMGG M LV G +V GYD + + + AA G A+SI
Sbjct: 4 ERIGFIGLGNMGGRMTRRLVDAGISVLGYDTAPERVKAA---GAQAASSIADVMKFADVV 60
Query: 361 XSILTSNKVVLDVYLGQRWRCGSCEKR 441
L +KVV V G C R
Sbjct: 61 MMSLPDSKVVEAVVEGDGGVLAHCRAR 87
>UniRef50_Q7VYY0 Cluster: Putative oxidoreductase; n=4;
Bordetella|Rep: Putative oxidoreductase - Bordetella
pertussis
Length = 305
Score = 46.0 bits (104), Expect = 0.001
Identities = 25/80 (31%), Positives = 42/80 (52%)
Frame = +2
Query: 407 GKDGVVAHAKKGSLLIDSSTIDXNVPQQIFPIALEKGLGFTDAPVSGRVMGCSKRYLAFM 586
G+ G++ + G+ ++D + + +++ +GL DAPVSG V S LA M
Sbjct: 86 GQPGLIDLLESGAAIVDMGSSNPADTRRLSEQLAARGLTLIDAPVSGAVAKASTGTLAIM 145
Query: 587 AGXRKKNFERSLPLLQVMGA 646
AG + + R P+L+ MGA
Sbjct: 146 AGAAEADLRRVRPILERMGA 165
>UniRef50_A3SJ77 Cluster: Probable oxidoreductase; n=1; Roseovarius
nubinhibens ISM|Rep: Probable oxidoreductase -
Roseovarius nubinhibens ISM
Length = 320
Score = 46.0 bits (104), Expect = 0.001
Identities = 29/76 (38%), Positives = 36/76 (47%)
Frame = +1
Query: 181 KNVAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGVTPANSIXXXXXXXXXX 360
+ VAF+GLG MG MAA LV G VRG D L A + G PA S+
Sbjct: 12 RRVAFIGLGTMGSGMAARLVAAGHEVRGVDIDSARLAAFEEVGGLPAASVAEACDGAEII 71
Query: 361 XSILTSNKVVLDVYLG 408
+IL + V + LG
Sbjct: 72 MTILPRDTHVRQICLG 87
Score = 41.1 bits (92), Expect = 0.036
Identities = 24/74 (32%), Positives = 32/74 (43%)
Frame = +2
Query: 407 GKDGVVAHAKKGSLLIDSSTIDXNVPQQIFPIALEKGLGFTDAPVSGRVMGCSKRYLAFM 586
G G+ A G+L+I+ STI I KGL DAPV L M
Sbjct: 87 GAGGIADSAAPGTLVIEMSTISPEASLDIHDALTSKGLRVLDAPVGRTPKDAQNGALLIM 146
Query: 587 AGXRKKNFERSLPL 628
AG R ++F + P+
Sbjct: 147 AGGRAEDFADAAPV 160
>UniRef50_Q1N6I0 Cluster: Putative oxidoreductase protein; n=1;
Oceanobacter sp. RED65|Rep: Putative oxidoreductase
protein - Oceanobacter sp. RED65
Length = 289
Score = 45.6 bits (103), Expect = 0.002
Identities = 25/76 (32%), Positives = 39/76 (51%)
Frame = +2
Query: 407 GKDGVVAHAKKGSLLIDSSTIDXNVPQQIFPIALEKGLGFTDAPVSGRVMGCSKRYLAFM 586
GKD + ++ K G+L+ID +T + ++ LEK + + DAPVSG G L M
Sbjct: 78 GKDSLYSNLKPGTLVIDHTTTSAELACEMQAKLLEKQVDYVDAPVSGGEQGAISGQLTIM 137
Query: 587 AGXRKKNFERSLPLLQ 634
G + ER+ + Q
Sbjct: 138 CGGQALAAERAQGITQ 153
>UniRef50_Q41DK0 Cluster: 6-phosphogluconate dehydrogenase,
NAD-binding; n=2; Bacillaceae|Rep: 6-phosphogluconate
dehydrogenase, NAD-binding - Exiguobacterium sibiricum
255-15
Length = 293
Score = 45.2 bits (102), Expect = 0.002
Identities = 24/77 (31%), Positives = 41/77 (53%)
Frame = +1
Query: 181 KNVAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGVTPANSIXXXXXXXXXX 360
K + F+GLG MG M NL+K GF+V+GY+ +K+ ++G ++I
Sbjct: 3 KTIGFIGLGVMGQGMVRNLLKAGFSVKGYNRTKEKGLPLEQDGAVIVDTIQEAVTDVDVV 62
Query: 361 XSILTSNKVVLDVYLGQ 411
SI+ + V ++YL +
Sbjct: 63 ISIVGYPQDVEEIYLAE 79
>UniRef50_Q1IQE6 Cluster: 2-hydroxy-3-oxopropionate reductase
precursor; n=1; Acidobacteria bacterium Ellin345|Rep:
2-hydroxy-3-oxopropionate reductase precursor -
Acidobacteria bacterium (strain Ellin345)
Length = 282
Score = 45.2 bits (102), Expect = 0.002
Identities = 24/80 (30%), Positives = 38/80 (47%)
Frame = +2
Query: 404 WGKDGVVAHAKKGSLLIDSSTIDXNVPQQIFPIALEKGLGFTDAPVSGRVMGCSKRYLAF 583
+G GV + G +++DSSTI + KG + DAP++G +G L F
Sbjct: 70 FGDGGVEPVLRAGMVVVDSSTISPVETLKFAERVRAKGADYIDAPITGSKIGAESAQLIF 129
Query: 584 MAGXRKKNFERSLPLLQVMG 643
M G + + ++ PL MG
Sbjct: 130 MVGAKDETLKKLEPLFLQMG 149
>UniRef50_A7H7Z5 Cluster: 6-phosphogluconate dehydrogenase
NAD-binding; n=2; Anaeromyxobacter|Rep:
6-phosphogluconate dehydrogenase NAD-binding -
Anaeromyxobacter sp. Fw109-5
Length = 293
Score = 45.2 bits (102), Expect = 0.002
Identities = 26/88 (29%), Positives = 38/88 (43%)
Frame = +2
Query: 383 KSCSTCTWGKDGVVAHAKKGSLLIDSSTIDXNVPQQIFPIALEKGLGFTDAPVSGRVMGC 562
K+ T G DGV+ + G +L+D ST + + A +G GF PV G
Sbjct: 70 KALDTVLEGPDGVLEALRDGDVLVDMSTAGVRAARSVSERAAARGAGFVACPVLGSRSAA 129
Query: 563 SKRYLAFMAGXRKKNFERSLPLLQVMGA 646
+ L +AG ER+ P L + A
Sbjct: 130 EQAQLVLVAGGPAVARERARPALHAVSA 157
>UniRef50_A0QUD5 Cluster: 3-hydroxyisobutyrate dehydrogenase family
protein; n=1; Mycobacterium smegmatis str. MC2 155|Rep:
3-hydroxyisobutyrate dehydrogenase family protein -
Mycobacterium smegmatis (strain ATCC 700084 / mc(2)155)
Length = 326
Score = 45.2 bits (102), Expect = 0.002
Identities = 25/81 (30%), Positives = 43/81 (53%)
Frame = +2
Query: 407 GKDGVVAHAKKGSLLIDSSTIDXNVPQQIFPIALEKGLGFTDAPVSGRVMGCSKRYLAFM 586
G DG+VA+A+ G++L+D STI ++ ++ G+ F APV+G LA
Sbjct: 85 GDDGLVANARAGAVLVDCSTISPDMSARVRARCDRAGVHFLAAPVAGGPPVIESGGLAMA 144
Query: 587 AGXRKKNFERSLPLLQVMGAN 649
++ FE + +L+V+ N
Sbjct: 145 VSGDRQAFEHAADVLRVVAPN 165
Score = 33.9 bits (74), Expect = 5.4
Identities = 36/121 (29%), Positives = 53/121 (43%), Gaps = 5/121 (4%)
Frame = +1
Query: 181 KNVAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGVTPANSIXXXXXXXXXX 360
+ V FLGLGNMG MA LV G + Y+ + A G A S+
Sbjct: 11 QRVGFLGLGNMGRPMARRLVASGTPLTVYNRTAAKCAEFADLGCEVAESV-ARMGHCSVL 69
Query: 361 XSILTSNKVVLDVYLGQRWRCGSCEKRIASDRFEYDRXECS--PTDLSYSLR---ERAGI 525
++L ++ V VYLG + +A+ R +CS D+S +R +RAG+
Sbjct: 70 LTMLGTDDDVAQVYLGD-------DGLVANARAGAVLVDCSTISPDMSARVRARCDRAGV 122
Query: 526 H 528
H
Sbjct: 123 H 123
>UniRef50_Q89UN2 Cluster: Bll1384 protein; n=9; Bacteria|Rep:
Bll1384 protein - Bradyrhizobium japonicum
Length = 356
Score = 44.8 bits (101), Expect = 0.003
Identities = 28/101 (27%), Positives = 46/101 (45%)
Frame = +2
Query: 374 PAIKSCSTCTWGKDGVVAHAKKGSLLIDSSTIDXNVPQQIFPIALEKGLGFTDAPVSGRV 553
P++++ G +GV+ + ID ST+ + +I + ++ + D PVSG V
Sbjct: 119 PSLQASLEVATGTNGVI-EGSRVKRFIDLSTVGSTMASKIHGLLAKRDIVQIDCPVSGGV 177
Query: 554 MGCSKRYLAFMAGXRKKNFERSLPLLQVMGANSXTADRSGS 676
G K LA M K FE P L V+G ++ G+
Sbjct: 178 GGAEKGTLAVMVSGPKAEFELLKPALDVIGKVFFIGEKPGA 218
Score = 42.7 bits (96), Expect = 0.012
Identities = 24/89 (26%), Positives = 42/89 (47%)
Frame = +1
Query: 142 YTAARRAYSSNTDKNVAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGVTPA 321
++ +R ++ ++ F+GLGNMG MA L++ G + +D K+ ++ G TPA
Sbjct: 42 FSRQQRIINTRNTMDIGFIGLGNMGFPMARRLIEAGNRLVVFDTRKEVVDKLVARGATPA 101
Query: 322 NSIXXXXXXXXXXXSILTSNKVVLDVYLG 408
S + L S + L+V G
Sbjct: 102 TSPKDVADQVETVMASLPSLQASLEVATG 130
>UniRef50_Q73P00 Cluster: 3-hydroxyacid dehydrogenase family
protein; n=4; Bacteria|Rep: 3-hydroxyacid dehydrogenase
family protein - Treponema denticola
Length = 292
Score = 44.8 bits (101), Expect = 0.003
Identities = 25/80 (31%), Positives = 41/80 (51%)
Frame = +2
Query: 404 WGKDGVVAHAKKGSLLIDSSTIDXNVPQQIFPIALEKGLGFTDAPVSGRVMGCSKRYLAF 583
+G+ G++ AK G++ D +T + ++I+ A +K DAPVSG +G L+
Sbjct: 80 FGEKGLLKTAKPGTIFADMTTSSPILAKKIYDEAKKKECFSVDAPVSGGDIGAKNGTLSI 139
Query: 584 MAGXRKKNFERSLPLLQVMG 643
MAG + F+ P MG
Sbjct: 140 MAGGDESAFKELEPFFACMG 159
>UniRef50_A0JXR2 Cluster: 2-hydroxy-3-oxopropionate reductase; n=2;
Arthrobacter|Rep: 2-hydroxy-3-oxopropionate reductase -
Arthrobacter sp. (strain FB24)
Length = 333
Score = 44.8 bits (101), Expect = 0.003
Identities = 24/49 (48%), Positives = 33/49 (67%), Gaps = 1/49 (2%)
Frame = +1
Query: 181 KNVAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDAL-NAAAKNGVTPAN 324
K F+GLG MGG MAANL+K G+ V G++ S AL + AA+ G+ A+
Sbjct: 16 KRAGFVGLGLMGGPMAANLLKAGWNVTGWNRSAAALDDLAARGGMRAAD 64
Score = 38.3 bits (85), Expect = 0.25
Identities = 18/38 (47%), Positives = 22/38 (57%)
Frame = +2
Query: 530 DAPVSGRVMGCSKRYLAFMAGXRKKNFERSLPLLQVMG 643
DAPVSG G LA M G +++F+R LPL MG
Sbjct: 136 DAPVSGGTKGAEDGTLAIMVGAGEQDFQRLLPLFNAMG 173
>UniRef50_Q94B07 Cluster: Gamma hydroxybutyrate dehydrogenase; n=16;
cellular organisms|Rep: Gamma hydroxybutyrate
dehydrogenase - Arabidopsis thaliana (Mouse-ear cress)
Length = 289
Score = 44.8 bits (101), Expect = 0.003
Identities = 28/89 (31%), Positives = 38/89 (42%)
Frame = +2
Query: 410 KDGVVAHAKKGSLLIDSSTIDXNVPQQIFPIALEKGLGFTDAPVSGRVMGCSKRYLAFMA 589
K GV+ +G ID ST+D +I KG F + PVSG L +A
Sbjct: 77 KGGVLEQICEGKGYIDMSTVDAETSLKINEAITGKGGRFVEGPVSGSKKPAEDGQLIILA 136
Query: 590 GXRKKNFERSLPLLQVMGANSXTADRSGS 676
K FE S+P V+G S + G+
Sbjct: 137 AGDKALFEESIPAFDVLGKRSFYLGQVGN 165
Score = 33.9 bits (74), Expect = 5.4
Identities = 17/47 (36%), Positives = 26/47 (55%)
Frame = +1
Query: 187 VAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGVTPANS 327
V FLGLG MG M+ NL+K GF V ++ + + ++G + S
Sbjct: 3 VGFLGLGIMGKAMSMNLLKNGFKVTVWNRTLSKCDELVEHGASVCES 49
>UniRef50_Q1GJB9 Cluster: 6-phosphogluconate dehydrogenase
NAD-binding; n=1; Silicibacter sp. TM1040|Rep:
6-phosphogluconate dehydrogenase NAD-binding -
Silicibacter sp. (strain TM1040)
Length = 304
Score = 44.4 bits (100), Expect = 0.004
Identities = 22/45 (48%), Positives = 28/45 (62%)
Frame = +1
Query: 178 DKNVAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGV 312
+K +GLG MG MA +L+K GF V GYDP++ A AA GV
Sbjct: 6 NKRAGVIGLGAMGLGMARSLLKAGFAVSGYDPAETARENAAAAGV 50
Score = 41.9 bits (94), Expect = 0.020
Identities = 26/90 (28%), Positives = 40/90 (44%)
Frame = +2
Query: 416 GVVAHAKKGSLLIDSSTIDXNVPQQIFPIALEKGLGFTDAPVSGRVMGCSKRYLAFMAGX 595
G +A +++D+ST + + + G GF DAPVSG G + L+ M G
Sbjct: 87 GHLAQTGAARVIVDTSTSEAATSRTLAAELSALGHGFLDAPVSGGPAGAASGQLSVMLGG 146
Query: 596 RKKNFERSLPLLQVMGANSXTADRSGSXXV 685
+ E + P L+ M A SG+ V
Sbjct: 147 ETQWLEAARPALEAMAAKILHVGPSGAGNV 176
>UniRef50_Q84VC8 Cluster: Gamma hydroxybutyrate dehydrogenase-like
protein; n=3; Magnoliophyta|Rep: Gamma hydroxybutyrate
dehydrogenase-like protein - Oryza sativa subsp.
japonica (Rice)
Length = 293
Score = 44.4 bits (100), Expect = 0.004
Identities = 25/81 (30%), Positives = 37/81 (45%)
Frame = +2
Query: 410 KDGVVAHAKKGSLLIDSSTIDXNVPQQIFPIALEKGLGFTDAPVSGRVMGCSKRYLAFMA 589
KDGV+ +G +D ST+D +I +KG F +APVSG L +A
Sbjct: 77 KDGVLEQIGEGKGYVDMSTVDAATSCKISEAIKQKGGAFVEAPVSGSKKPAEDGQLVILA 136
Query: 590 GXRKKNFERSLPLLQVMGANS 652
K ++ +P V+G S
Sbjct: 137 AGDKVLYDDMVPAFDVLGKKS 157
Score = 35.1 bits (77), Expect = 2.3
Identities = 22/49 (44%), Positives = 27/49 (55%), Gaps = 4/49 (8%)
Frame = +1
Query: 187 VAFLGLGNMGGFMAANLVKKGFTV----RGYDPSKDALNAAAKNGVTPA 321
V FLGLG MG MAANL++ GF V R ++ + A G TPA
Sbjct: 3 VGFLGLGIMGKAMAANLLRHGFRVTVWNRTLSKCQELVALGAAVGETPA 51
>UniRef50_Q1YHQ4 Cluster: Putative 2-hydroxy-3-oxopropionate
reductase; n=1; Aurantimonas sp. SI85-9A1|Rep: Putative
2-hydroxy-3-oxopropionate reductase - Aurantimonas sp.
SI85-9A1
Length = 292
Score = 44.0 bits (99), Expect = 0.005
Identities = 28/80 (35%), Positives = 39/80 (48%), Gaps = 1/80 (1%)
Frame = +2
Query: 407 GKDGVVAHAK-KGSLLIDSSTIDXNVPQQIFPIALEKGLGFTDAPVSGRVMGCSKRYLAF 583
G DG+VA K G ++D ST + V Q+ G F DAPVSG LA
Sbjct: 77 GADGLVASRKLSGRTVVDFSTTEMAVTHQVAAAIEAVGGRFVDAPVSGGPGAAETGTLAI 136
Query: 584 MAGXRKKNFERSLPLLQVMG 643
M G ++ E + P+L+ +G
Sbjct: 137 MFGGSEQAAEAARPMLEQLG 156
Score = 39.1 bits (87), Expect = 0.14
Identities = 23/74 (31%), Positives = 34/74 (45%)
Frame = +1
Query: 187 VAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGVTPANSIXXXXXXXXXXXS 366
+ F+GLG MG L + + V G+D + ++AAA GV PA S+
Sbjct: 4 IGFIGLGLMGSGFTKRLRELDYRVIGHDREAEKVSAAAAWGVEPAGSLAALCAEADIIAL 63
Query: 367 ILTSNKVVLDVYLG 408
LT++ V V G
Sbjct: 64 CLTTSDAVASVVTG 77
>UniRef50_Q4Q7T9 Cluster: 2-hydroxy-3-oxopropionate reductase,
putative; n=6; Trypanosomatidae|Rep:
2-hydroxy-3-oxopropionate reductase, putative -
Leishmania major
Length = 299
Score = 44.0 bits (99), Expect = 0.005
Identities = 28/81 (34%), Positives = 42/81 (51%), Gaps = 1/81 (1%)
Frame = +2
Query: 404 WGKDGVVAHAKKGSLLIDSSTIDXNVPQQIFP-IALEKGLGFTDAPVSGRVMGCSKRYLA 580
+G +GV A +G++ +D+STI +V Q+I + EK + DAPVSG +G L
Sbjct: 75 FGPNGVAAGICEGAIFVDNSTIKPSVAQEIARRLWKEKKVRALDAPVSGGDIGARNGTLT 134
Query: 581 FMAGXRKKNFERSLPLLQVMG 643
M G LP+L +G
Sbjct: 135 VMVGGDAAALATVLPVLLAVG 155
>UniRef50_Q8TUC1 Cluster: Predicted protein; n=4;
Methanosarcinaceae|Rep: Predicted protein -
Methanosarcina acetivorans
Length = 259
Score = 44.0 bits (99), Expect = 0.005
Identities = 25/64 (39%), Positives = 32/64 (50%), Gaps = 1/64 (1%)
Frame = +1
Query: 130 TQCLYTAARRAYSSNTDKNVAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKN- 306
T +Y Y K+V +GLG +G AA+LV KGF V GYD K L +
Sbjct: 125 TGIIYAEIASRYMKADSKDVLAVGLGKVGFPGAAHLVNKGFRVYGYDADKALLEKTVSDL 184
Query: 307 GVTP 318
G+TP
Sbjct: 185 GITP 188
>UniRef50_Q89HA0 Cluster: Oxidoreductase; n=1; Bradyrhizobium
japonicum|Rep: Oxidoreductase - Bradyrhizobium japonicum
Length = 313
Score = 43.6 bits (98), Expect = 0.007
Identities = 25/80 (31%), Positives = 39/80 (48%), Gaps = 1/80 (1%)
Frame = +2
Query: 404 WGKDGVVAHAKKGSLLIDSSTIDXNVPQQIFP-IALEKGLGFTDAPVSGRVMGCSKRYLA 580
+G +G+ G L++D S+I + + + + G G+ DAPVSG G + LA
Sbjct: 98 FGAEGLSTAPGAGKLVVDFSSIHPDAARDLATRLKAANGAGWIDAPVSGGTKGAEEGTLA 157
Query: 581 FMAGXRKKNFERSLPLLQVM 640
MAG + ER P + M
Sbjct: 158 IMAGGDASDIERVRPYVLTM 177
>UniRef50_Q18X68 Cluster: 6-phosphogluconate dehydrogenase,
NAD-binding; n=2; Desulfitobacterium hafniense|Rep:
6-phosphogluconate dehydrogenase, NAD-binding -
Desulfitobacterium hafniense (strain DCB-2)
Length = 298
Score = 43.6 bits (98), Expect = 0.007
Identities = 24/76 (31%), Positives = 39/76 (51%)
Frame = +2
Query: 407 GKDGVVAHAKKGSLLIDSSTIDXNVPQQIFPIALEKGLGFTDAPVSGRVMGCSKRYLAFM 586
G+ G+ + G +++D+STI+ + +I G+ F DAPVSG + L M
Sbjct: 75 GETGLKKVLRAGQIIVDTSTINYSTTLEIGKQLESVGVEFIDAPVSGMESRAKEGTLTTM 134
Query: 587 AGXRKKNFERSLPLLQ 634
G +++ FE P LQ
Sbjct: 135 CGGKQELFENVKPYLQ 150
Score = 35.1 bits (77), Expect = 2.3
Identities = 24/75 (32%), Positives = 34/75 (45%)
Frame = +1
Query: 187 VAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGVTPANSIXXXXXXXXXXXS 366
+ F+GLG MG MA NL+K G + YD + + G A I S
Sbjct: 3 LGFIGLGQMGKHMALNLLKSGEELIVYDQRPASYPEFEQRGARTAAQIRDVAEADIIFCS 62
Query: 367 ILTSNKVVLDVYLGQ 411
L +++VV V LG+
Sbjct: 63 -LPNSEVVCQVVLGE 76
>UniRef50_A3H5R1 Cluster: 6-phosphogluconate dehydrogenase,
NAD-binding; n=1; Caldivirga maquilingensis IC-167|Rep:
6-phosphogluconate dehydrogenase, NAD-binding -
Caldivirga maquilingensis IC-167
Length = 295
Score = 43.6 bits (98), Expect = 0.007
Identities = 23/76 (30%), Positives = 42/76 (55%)
Frame = +2
Query: 407 GKDGVVAHAKKGSLLIDSSTIDXNVPQQIFPIALEKGLGFTDAPVSGRVMGCSKRYLAFM 586
G++GV+ K+GSL+I+ STI + ++ EKG DAP+ G + KR +
Sbjct: 78 GENGVINGIKQGSLVIEMSTISPSTSIELANKIKEKGGLMVDAPIIGTSILIEKREAVVL 137
Query: 587 AGXRKKNFERSLPLLQ 634
G ++ +ER+ +++
Sbjct: 138 IGGEREAYERAYEVVK 153
>UniRef50_O33730 Cluster: Uncharacterized oxidoreductase Sfri_1503;
n=167; Bacteria|Rep: Uncharacterized oxidoreductase
Sfri_1503 - Shewanella frigidimarina (strain NCIMB 400)
Length = 291
Score = 43.6 bits (98), Expect = 0.007
Identities = 28/94 (29%), Positives = 43/94 (45%)
Frame = +2
Query: 407 GKDGVVAHAKKGSLLIDSSTIDXNVPQQIFPIALEKGLGFTDAPVSGRVMGCSKRYLAFM 586
G+ G+V G++L+D +T +V ++I + F DAPVSG G L M
Sbjct: 78 GEHGIVHGMHAGAILVDHTTASADVAREIAAYIEPLNIAFLDAPVSGGQAGAENGALTVM 137
Query: 587 AGXRKKNFERSLPLLQVMGANSXTADRSGSXXVG 688
G + +F+ P V+ A S A+ G G
Sbjct: 138 MGGDQAHFDTVKP---VISAYSRCAELLGPVGAG 168
>UniRef50_Q84H84 Cluster: Putative oxidoreductase; n=1; Arthrobacter
sp. BP2|Rep: Putative oxidoreductase - Arthrobacter sp.
BP2
Length = 278
Score = 42.7 bits (96), Expect = 0.012
Identities = 21/50 (42%), Positives = 29/50 (58%)
Frame = +1
Query: 181 KNVAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGVTPANSI 330
K + F+GLG MG MA NL + GF V GYD + + A G+T A ++
Sbjct: 3 KKIGFVGLGTMGLPMAVNLNRAGFEVIGYDAFEGSRQKAIAAGITMAETL 52
>UniRef50_Q3W9W7 Cluster: 6-phosphogluconate dehydrogenase, NAD
binding domain; n=2; Frankia sp. EAN1pec|Rep:
6-phosphogluconate dehydrogenase, NAD binding domain -
Frankia sp. EAN1pec
Length = 286
Score = 42.7 bits (96), Expect = 0.012
Identities = 25/76 (32%), Positives = 35/76 (46%), Gaps = 1/76 (1%)
Frame = +2
Query: 449 LIDSSTIDXNVPQQIFPIALEKGLGFTDAPVSGRVMGCSKRYLAFMAGXRKKNFERSLPL 628
++D+STI + Q+I + G+G+ DAPVSG V G R L M R P+
Sbjct: 88 VVDTSTIGVSAAQRITDLLAASGIGYVDAPVSGGVTGARARTLTVMYAGTDDACARVEPV 147
Query: 629 LQVMG-ANSXTADRSG 673
L + DR G
Sbjct: 148 LAALSDRRRRVGDRPG 163
Score = 33.9 bits (74), Expect = 5.4
Identities = 15/32 (46%), Positives = 22/32 (68%)
Frame = +1
Query: 175 TDKNVAFLGLGNMGGFMAANLVKKGFTVRGYD 270
T +V F+GLGNMGG +AAN+ + G + +D
Sbjct: 2 TAPSVGFVGLGNMGGALAANVAQFGLDLVVHD 33
>UniRef50_Q13LQ9 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=11;
Proteobacteria|Rep: 3-hydroxyisobutyrate dehydrogenase -
Burkholderia xenovorans (strain LB400)
Length = 296
Score = 42.7 bits (96), Expect = 0.012
Identities = 28/98 (28%), Positives = 41/98 (41%)
Frame = +2
Query: 416 GVVAHAKKGSLLIDSSTIDXNVPQQIFPIALEKGLGFTDAPVSGRVMGCSKRYLAFMAGX 595
G A KG+++ID S+ + + + + L + DAPVSG V + LA + G
Sbjct: 85 GWAARLAKGAVVIDMSSSEPERSRALGKTLEAQRLAYLDAPVSGGVKRAKEGTLAILVGG 144
Query: 596 RKKNFERSLPLLQVMGANSXTADRSGSXXVG*XXXXYV 709
R PLL MG N +G+ YV
Sbjct: 145 HADVLARCKPLLDAMGTNVLHIGTAGAGHAAKALNNYV 182
>UniRef50_A7PEG7 Cluster: Chromosome chr11 scaffold_13, whole genome
shotgun sequence; n=2; Vitis vinifera|Rep: Chromosome
chr11 scaffold_13, whole genome shotgun sequence - Vitis
vinifera (Grape)
Length = 348
Score = 42.7 bits (96), Expect = 0.012
Identities = 24/76 (31%), Positives = 36/76 (47%)
Frame = +2
Query: 416 GVVAHAKKGSLLIDSSTIDXNVPQQIFPIALEKGLGFTDAPVSGRVMGCSKRYLAFMAGX 595
G ++ + G +L+D +T D ++ +I A +G DAPVSG G LA AG
Sbjct: 128 GALSGLRPGGVLVDMTTSDPSLAAEIASSAASRGCFSVDAPVSGGDRGAKNATLAIFAGG 187
Query: 596 RKKNFERSLPLLQVMG 643
+ R PL +G
Sbjct: 188 DESVVRRLNPLFSHLG 203
>UniRef50_Q6C351 Cluster: Yarrowia lipolytica chromosome F of strain
CLIB122 of Yarrowia lipolytica; n=1; Yarrowia
lipolytica|Rep: Yarrowia lipolytica chromosome F of
strain CLIB122 of Yarrowia lipolytica - Yarrowia
lipolytica (Candida lipolytica)
Length = 334
Score = 42.7 bits (96), Expect = 0.012
Identities = 27/85 (31%), Positives = 38/85 (44%), Gaps = 5/85 (5%)
Frame = +2
Query: 434 KKGSLLIDSSTIDXNVPQQIFPIALEK--GLGFTDAPVSGRVMGCSKRYLAFMAGXRKKN 607
K + +D STID + + +K F DAPVSG V+G K L FM G K
Sbjct: 117 KTSKIFVDCSTIDTQTSIECGKLVTDKDASAAFVDAPVSGGVVGAEKGTLTFMVGCNKDK 176
Query: 608 ---FERSLPLLQVMGANSXTADRSG 673
+++ LL++MG G
Sbjct: 177 QQVYKQVEELLKLMGGRIVNCGTQG 201
>UniRef50_A0GPK7 Cluster: 6-phosphogluconate dehydrogenase,
NAD-binding; n=4; Burkholderia|Rep: 6-phosphogluconate
dehydrogenase, NAD-binding - Burkholderia phytofirmans
PsJN
Length = 297
Score = 42.3 bits (95), Expect = 0.015
Identities = 29/92 (31%), Positives = 44/92 (47%), Gaps = 1/92 (1%)
Frame = +2
Query: 404 WGKDGVVAHAKKGSLLIDSSTIDXNVPQQIFPIALEK-GLGFTDAPVSGRVMGCSKRYLA 580
+G DG+ A++G+ L+D ST+ + + E+ G + DAPVSG G + LA
Sbjct: 80 FGVDGLANRARRGATLVDHSTLAPSQTRAFARRWREQTGGDWIDAPVSGGTSGAAAGTLA 139
Query: 581 FMAGXRKKNFERSLPLLQVMGANSXTADRSGS 676
MAG E P+L+ A SG+
Sbjct: 140 IMAGGDATLIETLTPILRGYAARVTRMGGSGA 171
>UniRef50_Q4Q9Z1 Cluster: Dehydrogenase-like protein; n=6;
Trypanosomatidae|Rep: Dehydrogenase-like protein -
Leishmania major
Length = 431
Score = 42.3 bits (95), Expect = 0.015
Identities = 21/88 (23%), Positives = 42/88 (47%)
Frame = +2
Query: 413 DGVVAHAKKGSLLIDSSTIDXNVPQQIFPIALEKGLGFTDAPVSGRVMGCSKRYLAFMAG 592
+ +V +A+ G +++D +T+D + ++ A +G F DAP+SG L M G
Sbjct: 97 EALVTNARPGQIIVDHTTVDMELSRECAHEAERRGAVFLDAPMSGSPKQAFNNQLVLMVG 156
Query: 593 XRKKNFERSLPLLQVMGANSXTADRSGS 676
+ +R P+ ++ + +GS
Sbjct: 157 GPAEQVQRVSPIFRMYADHIHHMGANGS 184
>UniRef50_Q55JR1 Cluster: Putative uncharacterized protein; n=2;
Filobasidiella neoformans|Rep: Putative uncharacterized
protein - Cryptococcus neoformans (Filobasidiella
neoformans)
Length = 605
Score = 42.3 bits (95), Expect = 0.015
Identities = 19/47 (40%), Positives = 30/47 (63%)
Frame = +1
Query: 187 VAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGVTPANS 327
V ++GLG MG MAA+LV +G+ V+ +D +L A+ G P++S
Sbjct: 9 VGWIGLGAMGSGMAASLVSQGYKVQAFDVYPPSLKRVAEQGAIPSSS 55
>UniRef50_Q98I20 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=2;
Alphaproteobacteria|Rep: 3-hydroxyisobutyrate
dehydrogenase - Rhizobium loti (Mesorhizobium loti)
Length = 305
Score = 41.9 bits (94), Expect = 0.020
Identities = 18/49 (36%), Positives = 30/49 (61%)
Frame = +1
Query: 181 KNVAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGVTPANS 327
++ AF+GLG++GG +A +L++ GF + +D A+ G T ANS
Sbjct: 3 ESYAFIGLGHLGGNLAPSLIRNGFAITVFDRDPAAVERLVTLGATAANS 51
>UniRef50_Q2JEN4 Cluster: 6-phosphogluconate dehydrogenase,
NAD-binding; n=1; Frankia sp. CcI3|Rep:
6-phosphogluconate dehydrogenase, NAD-binding - Frankia
sp. (strain CcI3)
Length = 290
Score = 41.9 bits (94), Expect = 0.020
Identities = 19/46 (41%), Positives = 26/46 (56%)
Frame = +1
Query: 187 VAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGVTPAN 324
+ F+GLG MG MA NL+ G TV ++ S D + A G PA+
Sbjct: 3 IGFIGLGGMGSAMARNLIDAGHTVLAWNRSPDPVTELAAAGAVPAS 48
>UniRef50_Q9LNP0 Cluster: F1L3.35; n=8; Magnoliophyta|Rep: F1L3.35 -
Arabidopsis thaliana (Mouse-ear cress)
Length = 387
Score = 41.9 bits (94), Expect = 0.020
Identities = 24/79 (30%), Positives = 35/79 (44%)
Frame = +2
Query: 407 GKDGVVAHAKKGSLLIDSSTIDXNVPQQIFPIALEKGLGFTDAPVSGRVMGCSKRYLAFM 586
GK+G + G +D ST+D I + G F +APVSG L F+
Sbjct: 171 GKNGAIFGISSGKGYVDVSTVDVASSILISKQIKDTGALFLEAPVSGSKKPAEDGQLIFL 230
Query: 587 AGXRKKNFERSLPLLQVMG 643
K +E++ P L +MG
Sbjct: 231 TAGDKPLYEKAAPFLDIMG 249
>UniRef50_Q49A26 Cluster: Cytokine-like nuclear factor n-pac; n=46;
Euteleostomi|Rep: Cytokine-like nuclear factor n-pac -
Homo sapiens (Human)
Length = 553
Score = 41.9 bits (94), Expect = 0.020
Identities = 23/90 (25%), Positives = 39/90 (43%)
Frame = +2
Query: 383 KSCSTCTWGKDGVVAHAKKGSLLIDSSTIDXNVPQQIFPIALEKGLGFTDAPVSGRVMGC 562
K+ G GV+ + G +D ST+D + ++ + + +G F +APVSG
Sbjct: 335 KAAKDLVLGPSGVLQGIRPGKCYVDMSTVDADTVTELAQVIVSRGGRFLEAPVSGNQQLS 394
Query: 563 SKRYLAFMAGXRKKNFERSLPLLQVMGANS 652
+ L +A + +E Q MG S
Sbjct: 395 NDGMLVILAAGDRGLYEDCSSCFQTMGKTS 424
Score = 39.1 bits (87), Expect = 0.14
Identities = 24/72 (33%), Positives = 37/72 (51%), Gaps = 4/72 (5%)
Frame = +1
Query: 127 STQCLYTAARRAYSSNTDKNVAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDA----LNA 294
S Q + A + TDK + FLGLG MG + +NL+K G TV ++ + + +
Sbjct: 250 SIQAADSTAVNGSITPTDKKIGFLGLGLMGSGIVSNLLKMGHTVTVWNRTAEKCDLFIQE 309
Query: 295 AAKNGVTPANSI 330
A+ G TPA +
Sbjct: 310 GARLGRTPAEVV 321
>UniRef50_Q830A7 Cluster: 2-hydroxy-3-oxopropionate reductase; n=7;
Firmicutes|Rep: 2-hydroxy-3-oxopropionate reductase -
Enterococcus faecalis (Streptococcus faecalis)
Length = 296
Score = 41.5 bits (93), Expect = 0.027
Identities = 21/80 (26%), Positives = 39/80 (48%)
Frame = +2
Query: 404 WGKDGVVAHAKKGSLLIDSSTIDXNVPQQIFPIALEKGLGFTDAPVSGRVMGCSKRYLAF 583
+ + G+ G +++D +T + ++I A E G DAPVSG +G L
Sbjct: 76 FNETGIFQADLTGKIVVDLTTSTPTLAEKIAKKAAEVGAHALDAPVSGGDLGAKNGTLTI 135
Query: 584 MAGXRKKNFERSLPLLQVMG 643
M G +++++ LP+ + G
Sbjct: 136 MVGGDQESYDTVLPIFKTFG 155
>UniRef50_Q7WNK6 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=1;
Bordetella bronchiseptica|Rep: 3-hydroxyisobutyrate
dehydrogenase - Bordetella bronchiseptica (Alcaligenes
bronchisepticus)
Length = 306
Score = 41.5 bits (93), Expect = 0.027
Identities = 20/48 (41%), Positives = 26/48 (54%)
Frame = +1
Query: 187 VAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGVTPANSI 330
+ F+GLG MGG + +L G V YD A+ AAA G PA S+
Sbjct: 9 IGFIGLGAMGGPICGHLAAAGHDVAAYDIQPAAVQAAAARGARPAASV 56
>UniRef50_Q39FA8 Cluster: 2-hydroxy-3-oxopropionate reductase; n=22;
Burkholderiales|Rep: 2-hydroxy-3-oxopropionate reductase
- Burkholderia sp. (strain 383) (Burkholderia cepacia
(strain ATCC 17760/ NCIB 9086 / R18194))
Length = 287
Score = 41.5 bits (93), Expect = 0.027
Identities = 24/69 (34%), Positives = 35/69 (50%)
Frame = +2
Query: 425 AHAKKGSLLIDSSTIDXNVPQQIFPIALEKGLGFTDAPVSGRVMGCSKRYLAFMAGXRKK 604
A A++ ++D S+I + A G+G+ DAPVSG V G LA MAG R
Sbjct: 75 AAARRLQRIVDHSSIPPAATRDYAARATALGVGWVDAPVSGGVPGAQAGTLAVMAGGRAA 134
Query: 605 NFERSLPLL 631
+ + PL+
Sbjct: 135 DLDAVRPLI 143
>UniRef50_Q392H4 Cluster: 6-phosphogluconate dehydrogenase,
NAD-binding; n=8; Bacteria|Rep: 6-phosphogluconate
dehydrogenase, NAD-binding - Burkholderia sp. (strain
383) (Burkholderia cepacia (strain ATCC 17760/ NCIB 9086
/ R18194))
Length = 292
Score = 41.5 bits (93), Expect = 0.027
Identities = 22/52 (42%), Positives = 34/52 (65%), Gaps = 4/52 (7%)
Frame = +1
Query: 187 VAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGV----TPANSI 330
VA LG+G MG +A NL ++GFTVR ++ ++ +A A +GV TPA ++
Sbjct: 12 VAVLGIGVMGAPIARNLARQGFTVRAWNRTRAKADALAADGVAAFATPAETV 63
>UniRef50_Q12H32 Cluster: 6-phosphogluconate dehydrogenase,
NAD-binding precursor; n=1; Polaromonas sp. JS666|Rep:
6-phosphogluconate dehydrogenase, NAD-binding precursor
- Polaromonas sp. (strain JS666 / ATCC BAA-500)
Length = 297
Score = 41.5 bits (93), Expect = 0.027
Identities = 21/75 (28%), Positives = 40/75 (53%)
Frame = +2
Query: 407 GKDGVVAHAKKGSLLIDSSTIDXNVPQQIFPIALEKGLGFTDAPVSGRVMGCSKRYLAFM 586
G DGV++ A G ++ID+ST + +++ + E+G+ DAP++ + L M
Sbjct: 78 GPDGVLSRALAGLIVIDTSTSEPESTRRLAALCAERGVTLVDAPLARTPVEAELGRLNTM 137
Query: 587 AGXRKKNFERSLPLL 631
G + F++ P+L
Sbjct: 138 VGAEQAVFDKIRPVL 152
>UniRef50_Q0FFH2 Cluster: Putative 2-hydroxyacid dehydrogenase; n=2;
Alphaproteobacteria|Rep: Putative 2-hydroxyacid
dehydrogenase - alpha proteobacterium HTCC2255
Length = 303
Score = 41.5 bits (93), Expect = 0.027
Identities = 21/79 (26%), Positives = 41/79 (51%)
Frame = +2
Query: 407 GKDGVVAHAKKGSLLIDSSTIDXNVPQQIFPIALEKGLGFTDAPVSGRVMGCSKRYLAFM 586
G++G++ G + +D +T + +++ ++ G DAPV+G V G +
Sbjct: 76 GENGLLHSMGPGQVWVDLTTNQPELARELAQEIIDTGAIAIDAPVTGAVDGARNGNMTQF 135
Query: 587 AGXRKKNFERSLPLLQVMG 643
AG K+ ER P++++MG
Sbjct: 136 AGGDKETIERIRPVMELMG 154
>UniRef50_A3JU55 Cluster: Predicted dehydrogenase, with
NAD(P)-binding Rossmann-fold domain; n=2; Bacteria|Rep:
Predicted dehydrogenase, with NAD(P)-binding
Rossmann-fold domain - Rhodobacterales bacterium
HTCC2150
Length = 302
Score = 41.5 bits (93), Expect = 0.027
Identities = 23/81 (28%), Positives = 39/81 (48%)
Frame = +2
Query: 404 WGKDGVVAHAKKGSLLIDSSTIDXNVPQQIFPIALEKGLGFTDAPVSGRVMGCSKRYLAF 583
+G+ G++AH KG +I S+TI ++I + G+ D PVSG G L
Sbjct: 75 FGEGGLLAHMPKGGAVILSATIKPVEAEEIGAAMADSGIHLIDTPVSGGFPGAQGGTLTM 134
Query: 584 MAGXRKKNFERSLPLLQVMGA 646
MA + + P+++ + A
Sbjct: 135 MAAGVDEVLDTYAPVMEAVSA 155
Score = 33.5 bits (73), Expect = 7.1
Identities = 15/38 (39%), Positives = 22/38 (57%)
Frame = +1
Query: 196 LGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNG 309
+GLG+MG +A NL+K GF G D + + A + G
Sbjct: 6 IGLGDMGSGLAKNLLKAGFETTGIDMKPERMAAFVEMG 43
>UniRef50_Q8TT25 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=2;
Methanosarcina|Rep: 3-hydroxyisobutyrate dehydrogenase -
Methanosarcina acetivorans
Length = 300
Score = 41.5 bits (93), Expect = 0.027
Identities = 27/84 (32%), Positives = 41/84 (48%)
Frame = +2
Query: 392 STCTWGKDGVVAHAKKGSLLIDSSTIDXNVPQQIFPIALEKGLGFTDAPVSGRVMGCSKR 571
++ +G+DG++ AKKG L ID STID + + A + GL D PV G SK
Sbjct: 80 NSVAFGEDGLLNGAKKGCLWIDLSTIDPSSSVKHAEAAKKAGLERLDTPVVGSKDLASKG 139
Query: 572 YLAFMAGXRKKNFERSLPLLQVMG 643
L + G ++ + L +G
Sbjct: 140 ELIILVGGSQEVLRKHEKFLNKLG 163
>UniRef50_Q6KZX0 Cluster: 2-hydroxy-3-oxopropionate reductase; n=1;
Picrophilus torridus|Rep: 2-hydroxy-3-oxopropionate
reductase - Picrophilus torridus
Length = 280
Score = 41.5 bits (93), Expect = 0.027
Identities = 26/51 (50%), Positives = 28/51 (54%), Gaps = 2/51 (3%)
Frame = +1
Query: 184 NVAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNA--AAKNGVTPANSI 330
NV LGLG MG MA L+KK F V GYD +K A KN PA SI
Sbjct: 2 NVGVLGLGRMGSGMAYTLLKKNFNVTGYDVNKMAYGRFNGIKN-FKPAESI 51
>UniRef50_A7IE35 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=2;
Proteobacteria|Rep: 3-hydroxyisobutyrate dehydrogenase -
Xanthobacter sp. (strain Py2)
Length = 330
Score = 41.1 bits (92), Expect = 0.036
Identities = 22/84 (26%), Positives = 38/84 (45%)
Frame = +2
Query: 395 TCTWGKDGVVAHAKKGSLLIDSSTIDXNVPQQIFPIALEKGLGFTDAPVSGRVMGCSKRY 574
T +G DGV G++ + S+T+D + + + G + DAP+SG ++
Sbjct: 104 TILFGADGVAQTLADGAVFLSSATMDPEIARTLAARLEATGRLYLDAPISGGAQRAAEGA 163
Query: 575 LAFMAGXRKKNFERSLPLLQVMGA 646
L +A F ++ P L M A
Sbjct: 164 LTILASGSPAAFAKARPALDAMAA 187
Score = 35.5 bits (78), Expect = 1.8
Identities = 19/46 (41%), Positives = 27/46 (58%)
Frame = +1
Query: 190 AFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGVTPANS 327
A +GLG+MG MA +L + GF V G+D + A+ A G A+S
Sbjct: 36 AVIGLGSMGYGMAQSLKRAGFDVAGFDVNAAAVERFAAEGGRGASS 81
>UniRef50_A3K497 Cluster: Probable 6-phosphogluconate dehydrogenase
protein; n=1; Sagittula stellata E-37|Rep: Probable
6-phosphogluconate dehydrogenase protein - Sagittula
stellata E-37
Length = 298
Score = 40.7 bits (91), Expect = 0.047
Identities = 18/31 (58%), Positives = 22/31 (70%)
Frame = +1
Query: 178 DKNVAFLGLGNMGGFMAANLVKKGFTVRGYD 270
DK + F+GLGNMG MA +LV+ GF V YD
Sbjct: 3 DKLIGFIGLGNMGTAMARHLVRGGFEVLAYD 33
Score = 39.1 bits (87), Expect = 0.14
Identities = 22/80 (27%), Positives = 39/80 (48%), Gaps = 1/80 (1%)
Frame = +2
Query: 407 GKDGVVAHAKKGSLLIDSSTIDXNVPQQIFPIALEKGLGFTDAPVSGRVMGCSKRYLAFM 586
G+ G++ + G+L+ID+++ +++ + +G DAPVSG G L FM
Sbjct: 81 GEAGLLGQMQPGTLMIDTTSSPPEATRELAAVLNARGCHLVDAPVSGARAGAEAADLVFM 140
Query: 587 AGXRKKN-FERSLPLLQVMG 643
G ER+ +L +G
Sbjct: 141 IGCDDDAVLERTRAVLSCLG 160
>UniRef50_Q8VYC5 Cluster: Fructose-bisphosphate aldolase; n=12;
cellular organisms|Rep: Fructose-bisphosphate aldolase -
Arabidopsis thaliana (Mouse-ear cress)
Length = 1373
Score = 40.7 bits (91), Expect = 0.047
Identities = 22/47 (46%), Positives = 27/47 (57%)
Frame = +1
Query: 187 VAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGVTPANS 327
+ F+GLG MG MAA+L+K F+V GYD K L G ANS
Sbjct: 324 IGFIGLGAMGFGMAAHLLKSNFSVCGYDVYKPTLVRFENAGGLAANS 370
>UniRef50_A1CAY2 Cluster: Oxidoreductase, acting on the CH-OH group
of donors, NAD or NADP as acceptor; n=2;
Aspergillus|Rep: Oxidoreductase, acting on the CH-OH
group of donors, NAD or NADP as acceptor - Aspergillus
clavatus
Length = 436
Score = 40.7 bits (91), Expect = 0.047
Identities = 20/48 (41%), Positives = 29/48 (60%)
Frame = +1
Query: 187 VAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGVTPANSI 330
+ F+GLG MG MA NLV++G+ V GYD ++ G PA+S+
Sbjct: 6 IGFVGLGAMGFGMATNLVREGYPVVGYDVFPASVQRFQTAGGIPASSL 53
Score = 34.3 bits (75), Expect = 4.1
Identities = 23/82 (28%), Positives = 36/82 (43%), Gaps = 3/82 (3%)
Frame = +2
Query: 404 WGKDGVVAHAKKGSLLIDSSTIDXNVPQQIFPIALEKG---LGFTDAPVSGRVMGCSKRY 574
+G DG+V + + L ST+ + Q + G + F D PVSG +
Sbjct: 78 FGDDGIVQYLPPNATLFLCSTVPASYAQSVAAELQSLGRADIRFIDCPVSGGAKRAADGT 137
Query: 575 LAFMAGXRKKNFERSLPLLQVM 640
L+ MAG ++ +LQVM
Sbjct: 138 LSIMAGAPEEALNSGREILQVM 159
>UniRef50_O34969 Cluster: Uncharacterized oxidoreductase yfjR; n=1;
Bacillus subtilis|Rep: Uncharacterized oxidoreductase
yfjR - Bacillus subtilis
Length = 261
Score = 40.7 bits (91), Expect = 0.047
Identities = 25/82 (30%), Positives = 39/82 (47%)
Frame = +2
Query: 386 SCSTCTWGKDGVVAHAKKGSLLIDSSTIDXNVPQQIFPIALEKGLGFTDAPVSGRVMGCS 565
S ST T+G+DG++ + + I STI +++ EKG F APV GR +
Sbjct: 44 SVSTVTFGEDGLLEGLAENGIHISMSTISVEFSEKLAAAHAEKGQFFLAAPVLGRPDAAA 103
Query: 566 KRYLAFMAGXRKKNFERSLPLL 631
K L + + + + PLL
Sbjct: 104 KAALRIITAGPAEAKQAAKPLL 125
>UniRef50_P71825 Cluster: Uncharacterized oxidoreductase
Rv0770/MT0794; n=18; Corynebacterineae|Rep:
Uncharacterized oxidoreductase Rv0770/MT0794 -
Mycobacterium tuberculosis
Length = 295
Score = 40.7 bits (91), Expect = 0.047
Identities = 22/68 (32%), Positives = 33/68 (48%)
Frame = +2
Query: 413 DGVVAHAKKGSLLIDSSTIDXNVPQQIFPIALEKGLGFTDAPVSGRVMGCSKRYLAFMAG 592
+G+ HAK G+++ STI + +G+ DAPVSG +K LA M G
Sbjct: 84 NGLATHAKPGTIVAIHSTIADTTAVDLAEKLKPQGIHIVDAPVSGGAAAAAKGELAVMVG 143
Query: 593 XRKKNFER 616
+ F+R
Sbjct: 144 ADDEAFQR 151
>UniRef50_Q82ZC2 Cluster: 6-phosphogluconate dehydrogenase family
protein; n=16; Bacteria|Rep: 6-phosphogluconate
dehydrogenase family protein - Enterococcus faecalis
(Streptococcus faecalis)
Length = 299
Score = 40.3 bits (90), Expect = 0.062
Identities = 17/49 (34%), Positives = 33/49 (67%)
Frame = +1
Query: 184 NVAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGVTPANSI 330
++ F+GLG MG MA N+ ++G+ + G+D +K+A A + G++ +S+
Sbjct: 2 DIGFIGLGKMGLNMALNVHEQGWPIIGFDVTKEARATAREQGLSVVDSL 50
>UniRef50_A5VBF0 Cluster: 2-hydroxy-3-oxopropionate reductase
precursor; n=1; Sphingomonas wittichii RW1|Rep:
2-hydroxy-3-oxopropionate reductase precursor -
Sphingomonas wittichii RW1
Length = 298
Score = 40.3 bits (90), Expect = 0.062
Identities = 26/82 (31%), Positives = 38/82 (46%), Gaps = 1/82 (1%)
Frame = +2
Query: 404 WGKDGVVAHAKKGSLLIDSSTIDXNVPQQIFPIALEKG-LGFTDAPVSGRVMGCSKRYLA 580
+G+ G G+L++D STI + + E G + D PVSG V G LA
Sbjct: 77 FGEGGAARALAPGALVVDFSTIGPDATRGFAKRLAETGDAQWLDCPVSGGVAGAEAGTLA 136
Query: 581 FMAGXRKKNFERSLPLLQVMGA 646
+AG +R PLL ++ A
Sbjct: 137 ILAGGDAAAIDRVRPLLALLSA 158
>UniRef50_A0FZ96 Cluster: 6-phosphogluconate dehydrogenase,
NAD-binding; n=1; Burkholderia phymatum STM815|Rep:
6-phosphogluconate dehydrogenase, NAD-binding -
Burkholderia phymatum STM815
Length = 305
Score = 40.3 bits (90), Expect = 0.062
Identities = 27/95 (28%), Positives = 44/95 (46%), Gaps = 3/95 (3%)
Frame = +2
Query: 374 PAIKSCSTCTWGKDGVVAHAKKGSLLIDSSTIDXNVPQQIFPIALEK---GLGFTDAPVS 544
P + +G DG V G ++ID ++ VP + A + G+ DAPVS
Sbjct: 64 PRSSDVHSVLFGPDGAVEGLSDGKIVIDQTS---GVPAETRDFARQLADIGVALFDAPVS 120
Query: 545 GRVMGCSKRYLAFMAGXRKKNFERSLPLLQVMGAN 649
G + ++ +A K FE++LP+LQ + N
Sbjct: 121 GAMATAIAGTISIIASGPKDAFEKTLPVLQSISPN 155
>UniRef50_Q4WV01 Cluster: Oxidoreductase, acting on the CH-OH group
of donors, NAD or NADP as acceptor; n=7;
Pezizomycotina|Rep: Oxidoreductase, acting on the CH-OH
group of donors, NAD or NADP as acceptor - Aspergillus
fumigatus (Sartorya fumigata)
Length = 435
Score = 40.3 bits (90), Expect = 0.062
Identities = 19/48 (39%), Positives = 29/48 (60%)
Frame = +1
Query: 187 VAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGVTPANSI 330
+ F+GLG MG MA NLV++G+ V G+D ++ G PA+S+
Sbjct: 6 IGFVGLGAMGFGMATNLVREGYPVVGFDVFPASVQRFQSQGGIPASSL 53
Score = 37.9 bits (84), Expect = 0.33
Identities = 25/82 (30%), Positives = 37/82 (45%), Gaps = 3/82 (3%)
Frame = +2
Query: 404 WGKDGVVAHAKKGSLLIDSSTIDXNVPQQIFPIALEKG---LGFTDAPVSGRVMGCSKRY 574
+G DGVV K + L ST+ + Q + +G + F D PVSG +
Sbjct: 78 FGDDGVVQFLPKNATLFLCSTVPASYAQSVAAELQSRGRADIRFIDCPVSGGAKRAADGT 137
Query: 575 LAFMAGXRKKNFERSLPLLQVM 640
L+ MAG ++ +LQVM
Sbjct: 138 LSIMAGASEEALNSGREILQVM 159
>UniRef50_Q0UVR9 Cluster: Putative uncharacterized protein; n=1;
Phaeosphaeria nodorum|Rep: Putative uncharacterized
protein - Phaeosphaeria nodorum (Septoria nodorum)
Length = 288
Score = 40.3 bits (90), Expect = 0.062
Identities = 29/84 (34%), Positives = 44/84 (52%), Gaps = 3/84 (3%)
Frame = +2
Query: 410 KDGVVAHAK-KGSLLIDSSTIDXNVPQQIFPIALEKGLG-FTDAPVSGRVMGCSKRYLAF 583
K GV+A K +G L+++ STID +++ E+GLG + DAPVSG V L+
Sbjct: 43 KTGVIAARKDEGRLMLECSTIDVESTKEVGRKLKEEGLGTYIDAPVSGGVPAAEAGTLSM 102
Query: 584 MAGXRKKNFERSLP-LLQVMGANS 652
+ G + LP L ++G S
Sbjct: 103 LIGAPPPDPTSLLPSTLSLLGTPS 126
>UniRef50_Q8UBW3 Cluster: Oxidoredutase; n=1; Agrobacterium
tumefaciens str. C58|Rep: Oxidoredutase - Agrobacterium
tumefaciens (strain C58 / ATCC 33970)
Length = 300
Score = 39.9 bits (89), Expect = 0.082
Identities = 23/59 (38%), Positives = 32/59 (54%)
Frame = +2
Query: 416 GVVAHAKKGSLLIDSSTIDXNVPQQIFPIALEKGLGFTDAPVSGRVMGCSKRYLAFMAG 592
GV KG+++IDSS+I + ++ G+ DAPVSG V G + LA MAG
Sbjct: 87 GVAEALAKGAVVIDSSSIAPPIAREHSSRLQAMGIHHVDAPVSGGVPGATAGTLAIMAG 145
Score = 38.3 bits (85), Expect = 0.25
Identities = 20/49 (40%), Positives = 29/49 (59%)
Frame = +1
Query: 181 KNVAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGVTPANS 327
++VAF+G G MGG MA L+ GF+V+ ++ S D A +G A S
Sbjct: 10 RSVAFIGTGLMGGPMARRLLGTGFSVKVWNRSVDKAQALVADGAVLAAS 58
>UniRef50_Q89RT2 Cluster: Bll2680 protein; n=1; Bradyrhizobium
japonicum|Rep: Bll2680 protein - Bradyrhizobium
japonicum
Length = 300
Score = 39.9 bits (89), Expect = 0.082
Identities = 19/53 (35%), Positives = 30/53 (56%)
Frame = +1
Query: 169 SNTDKNVAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGVTPANS 327
++ +NVAF+G+G MG M+ + K G+ V +D S N A G++ A S
Sbjct: 2 TDASRNVAFIGIGKMGLPMSVLVAKAGYAVTAFDRSAARTNEARAQGISIAAS 54
Score = 36.7 bits (81), Expect = 0.77
Identities = 21/74 (28%), Positives = 34/74 (45%)
Frame = +2
Query: 407 GKDGVVAHAKKGSLLIDSSTIDXNVPQQIFPIALEKGLGFTDAPVSGRVMGCSKRYLAFM 586
G GV+A G++LI++ST+ ++ A +G+ + APVSG L
Sbjct: 81 GPAGVIAAMAPGAVLIETSTVSVEASTEVAASAQARGVLYLRAPVSGNASIVHTGALTCF 140
Query: 587 AGXRKKNFERSLPL 628
K F+ + PL
Sbjct: 141 VSGPKDAFDNAKPL 154
>UniRef50_Q89M84 Cluster: Blr4309 protein; n=6;
Bradyrhizobiaceae|Rep: Blr4309 protein - Bradyrhizobium
japonicum
Length = 293
Score = 39.9 bits (89), Expect = 0.082
Identities = 26/99 (26%), Positives = 44/99 (44%), Gaps = 1/99 (1%)
Frame = +2
Query: 392 STCTW-GKDGVVAHAKKGSLLIDSSTIDXNVPQQIFPIALEKGLGFTDAPVSGRVMGCSK 568
S W G G AK G++ I+ ST+ + +++ +GL + D PV+G +
Sbjct: 71 SRAVWLGPKGAAKTAKAGTIAIECSTVSYDHAREMGRELNARGLIYIDCPVTGLPDAAAA 130
Query: 569 RYLAFMAGXRKKNFERSLPLLQVMGANSXTADRSGSXXV 685
L + G + ER+ P L+ +G+ GS V
Sbjct: 131 GKLTLLVGADAADLERARPYLEPIGSTIRHFGAVGSGTV 169
Score = 33.5 bits (73), Expect = 7.1
Identities = 22/76 (28%), Positives = 33/76 (43%)
Frame = +1
Query: 187 VAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGVTPANSIXXXXXXXXXXXS 366
VAF+GLG MG MA + GFTV ++ SK G A S +
Sbjct: 4 VAFIGLGRMGHGMAGRYLDAGFTVTLWNRSKTKAEDLIARGAHWATSPEDAAIDADAVVT 63
Query: 367 ILTSNKVVLDVYLGQR 414
++ ++ V+LG +
Sbjct: 64 MVADDEASRAVWLGPK 79
>UniRef50_Q5LQR0 Cluster: 6-phosphogluconate dehydrogenase domain
protein; n=14; Proteobacteria|Rep: 6-phosphogluconate
dehydrogenase domain protein - Silicibacter pomeroyi
Length = 302
Score = 39.9 bits (89), Expect = 0.082
Identities = 24/82 (29%), Positives = 37/82 (45%)
Frame = +2
Query: 404 WGKDGVVAHAKKGSLLIDSSTIDXNVPQQIFPIALEKGLGFTDAPVSGRVMGCSKRYLAF 583
+G DGV+A ++G ++ID T ++I KG + DAP+ L
Sbjct: 84 YGDDGVLAGTREGQVVIDFGTSLPASTRRIGGDLAGKGATYLDAPLGRTPAHARDGLLNI 143
Query: 584 MAGXRKKNFERSLPLLQVMGAN 649
M K F+R P+L +G N
Sbjct: 144 MCSGDKATFDRVKPVLHTLGEN 165
>UniRef50_Q39MY1 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=2;
Burkholderia sp. 383|Rep: 3-hydroxyisobutyrate
dehydrogenase - Burkholderia sp. (strain 383)
(Burkholderia cepacia (strain ATCC 17760/ NCIB 9086 /
R18194))
Length = 303
Score = 39.9 bits (89), Expect = 0.082
Identities = 25/79 (31%), Positives = 38/79 (48%)
Frame = +2
Query: 407 GKDGVVAHAKKGSLLIDSSTIDXNVPQQIFPIALEKGLGFTDAPVSGRVMGCSKRYLAFM 586
G DGVV H L ++ STI ++ ++I ++G+ DAPVSG LA +
Sbjct: 80 GPDGVV-HGSAVRLYVEMSTIGQDMIERIGEGLAQRGIDIVDAPVSGGPSAARAGTLAML 138
Query: 587 AGXRKKNFERSLPLLQVMG 643
E+ PLL+ +G
Sbjct: 139 VSGMPSAVEQVSPLLERIG 157
Score = 34.3 bits (75), Expect = 4.1
Identities = 23/75 (30%), Positives = 31/75 (41%)
Frame = +1
Query: 184 NVAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGVTPANSIXXXXXXXXXXX 363
++ FLGLG MG MA L+ + + YDPS A+ G S
Sbjct: 6 DIGFLGLGKMGAPMAERLLGQACRLHVYDPSAQAVAPFVDGGAVAHASPRAVADAASIVF 65
Query: 364 SILTSNKVVLDVYLG 408
+ L + V L V LG
Sbjct: 66 ACLPNRDVSLAVGLG 80
>UniRef50_Q3W3N3 Cluster: Putative uncharacterized protein; n=1;
Frankia sp. EAN1pec|Rep: Putative uncharacterized
protein - Frankia sp. EAN1pec
Length = 315
Score = 39.9 bits (89), Expect = 0.082
Identities = 23/83 (27%), Positives = 39/83 (46%)
Frame = +2
Query: 395 TCTWGKDGVVAHAKKGSLLIDSSTIDXNVPQQIFPIALEKGLGFTDAPVSGRVMGCSKRY 574
T G G++ + GSL++ ST + A +G+ DAPVS S R
Sbjct: 85 TVVAGPGGLLETMRSGSLVVIHSTCSPRTCVDLAARARGRGITVLDAPVSNGAPDESGRQ 144
Query: 575 LAFMAGXRKKNFERSLPLLQVMG 643
L +AG +++ +R P+ ++ G
Sbjct: 145 LVVLAGGDRRDVDRCAPVFELFG 167
>UniRef50_Q1GF31 Cluster: 6-phosphogluconate dehydrogenase
NAD-binding; n=17; Proteobacteria|Rep:
6-phosphogluconate dehydrogenase NAD-binding -
Silicibacter sp. (strain TM1040)
Length = 325
Score = 39.9 bits (89), Expect = 0.082
Identities = 16/44 (36%), Positives = 27/44 (61%)
Frame = +1
Query: 187 VAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGVTP 318
+ F+GLGN+GG +A +L++ GF + YD + D + + G P
Sbjct: 3 IGFIGLGNVGGKLAGSLLRNGFDLTVYDLNPDLVAEYVEKGAQP 46
Score = 35.1 bits (77), Expect = 2.3
Identities = 20/88 (22%), Positives = 38/88 (43%)
Frame = +2
Query: 380 IKSCSTCTWGKDGVVAHAKKGSLLIDSSTIDXNVPQQIFPIALEKGLGFTDAPVSGRVMG 559
+ S + C + ++ + ++ ST D +++ + E+G + PVSG
Sbjct: 64 LPSPAACATVVEEMLPAVDSSKIWMEMSTTDAAEVKRLAALVSERGGSAMECPVSGGCHR 123
Query: 560 CSKRYLAFMAGXRKKNFERSLPLLQVMG 643
++ AG + FER LP L +G
Sbjct: 124 ADTGNISIFAGCDRATFERMLPTLTTLG 151
>UniRef50_A6R0U9 Cluster: Predicted protein; n=1; Ajellomyces
capsulatus NAm1|Rep: Predicted protein - Ajellomyces
capsulatus NAm1
Length = 444
Score = 39.9 bits (89), Expect = 0.082
Identities = 18/33 (54%), Positives = 25/33 (75%), Gaps = 1/33 (3%)
Frame = +1
Query: 175 TDK-NVAFLGLGNMGGFMAANLVKKGFTVRGYD 270
T+K ++ F+GLG MG MA NL+K G+ V+GYD
Sbjct: 3 TEKPSIGFVGLGLMGFGMATNLIKLGYVVKGYD 35
>UniRef50_Q4PCH4 Cluster: Putative uncharacterized protein; n=1;
Ustilago maydis|Rep: Putative uncharacterized protein -
Ustilago maydis (Smut fungus)
Length = 366
Score = 39.5 bits (88), Expect = 0.11
Identities = 28/93 (30%), Positives = 44/93 (47%), Gaps = 5/93 (5%)
Frame = +2
Query: 422 VAHAKKGSLLIDSSTIDXNVPQQ----IFPIALEKGLGFTDAPVSGRVMGCSKRYLAFMA 589
V A+ +L ID +T+D +V Q I DAPVSG V+G + L+FM
Sbjct: 130 VDDAQAKTLCIDCTTLDPDVAVQTATAIKNANANGAFDMIDAPVSGGVVGANAATLSFMV 189
Query: 590 G-XRKKNFERSLPLLQVMGANSXTADRSGSXXV 685
G F + P L +MG+ + ++G+ +
Sbjct: 190 GSDSSTTFASAEPYLSLMGSRAVHCGKNGNGLI 222
>UniRef50_Q1EPJ1 Cluster: 6-phosphogluconate dehydrogenase
NAD-binding domain-containing protein; n=8;
Magnoliophyta|Rep: 6-phosphogluconate dehydrogenase
NAD-binding domain-containing protein - Musa acuminata
(Banana)
Length = 314
Score = 39.1 bits (87), Expect = 0.14
Identities = 22/76 (28%), Positives = 37/76 (48%)
Frame = +2
Query: 416 GVVAHAKKGSLLIDSSTIDXNVPQQIFPIALEKGLGFTDAPVSGRVMGCSKRYLAFMAGX 595
G +A G +L+D ++ D + +++ A +G DAPVSG +G LA +AG
Sbjct: 95 GALAAIPPGGVLVDCTSSDPALAREVAAAARARGCWAVDAPVSGGDVGARDGTLAILAGG 154
Query: 596 RKKNFERSLPLLQVMG 643
+ PL + +G
Sbjct: 155 DEGVVHWLSPLFEALG 170
>UniRef50_Q2UHA9 Cluster: Predicted dehydrogenase; n=16;
Pezizomycotina|Rep: Predicted dehydrogenase -
Aspergillus oryzae
Length = 363
Score = 39.1 bits (87), Expect = 0.14
Identities = 34/110 (30%), Positives = 50/110 (45%), Gaps = 4/110 (3%)
Frame = +2
Query: 359 SFPY*PAIKSCSTCTWGKDGVVAHAKKGSLLIDSSTIDXNVPQQIFPIALEKGLG-FTDA 535
S P +K+ C + G + +K L ID+STID ++I G F DA
Sbjct: 122 SLPEPEHVKNVFYCML-RHGELPALEKERLFIDTSTIDPASSREIANAIHTTRQGRFVDA 180
Query: 536 PVSGRVMGCSKRYLAFMAGXRKKNFE---RSLPLLQVMGANSXTADRSGS 676
P+SG V+G L+FM G + E R +L +MG + SG+
Sbjct: 181 PMSGGVVGARAGTLSFMFGASSQTGELVDRVQSVLMLMGKKAWHMGNSGT 230
Score = 33.1 bits (72), Expect = 9.4
Identities = 14/26 (53%), Positives = 19/26 (73%)
Frame = +3
Query: 708 LMGLTGMATAECMNMGIKMGLXPKGL 785
L+ + +ATAE MN+GI+ GL PK L
Sbjct: 241 LLAINNIATAEVMNLGIRCGLDPKVL 266
>UniRef50_Q3W9L4 Cluster: Putative uncharacterized protein; n=1;
Frankia sp. EAN1pec|Rep: Putative uncharacterized
protein - Frankia sp. EAN1pec
Length = 294
Score = 38.7 bits (86), Expect = 0.19
Identities = 23/74 (31%), Positives = 36/74 (48%)
Frame = +2
Query: 413 DGVVAHAKKGSLLIDSSTIDXNVPQQIFPIALEKGLGFTDAPVSGRVMGCSKRYLAFMAG 592
DGV+A G +++ STI Q++ A ++ + DAPVSG ++R L M G
Sbjct: 92 DGVLAGMAAGGVVVIHSTIRPETCQRLATEAAKQEISIIDAPVSGGGDAAAQRRLLVMVG 151
Query: 593 XRKKNFERSLPLLQ 634
R P+L+
Sbjct: 152 GEDDAVARCRPVLE 165
>UniRef50_A4ENK2 Cluster: 3-demethylubiquinone-9
3-methyltransferase; n=5; Rhodobacteraceae|Rep:
3-demethylubiquinone-9 3-methyltransferase - Roseobacter
sp. CCS2
Length = 240
Score = 38.7 bits (86), Expect = 0.19
Identities = 19/34 (55%), Positives = 24/34 (70%)
Frame = +1
Query: 196 LGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAA 297
L LG GGFMA L ++G TV G DP+KDA+ +A
Sbjct: 53 LDLGCAGGFMAEALDERGATVVGIDPAKDAIASA 86
>UniRef50_Q7WCG3 Cluster: Putative uncharacterized protein; n=2;
Bordetella|Rep: Putative uncharacterized protein -
Bordetella parapertussis
Length = 296
Score = 38.3 bits (85), Expect = 0.25
Identities = 22/50 (44%), Positives = 28/50 (56%)
Frame = +1
Query: 181 KNVAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGVTPANSI 330
K VAF+G+GNMG MA + GF + D + D L A A+ GV SI
Sbjct: 5 KTVAFIGVGNMGAPMARCARRAGFELIVCDRNPDVLAAFAQEGVRVTASI 54
Score = 35.5 bits (78), Expect = 1.8
Identities = 19/57 (33%), Positives = 24/57 (42%)
Frame = +2
Query: 515 GLGFTDAPVSGRVMGCSKRYLAFMAGXRKKNFERSLPLLQVMGANSXTADRSGSXXV 685
G DAPVSG ++G L M G + E PL+Q MG GS +
Sbjct: 117 GARLVDAPVSGGIVGAEAGTLTIMMGGETADVEAVRPLMQAMGERLFHCGALGSAEI 173
>UniRef50_Q2BFK1 Cluster: Oxidoreductase; n=1; Bacillus sp. NRRL
B-14911|Rep: Oxidoreductase - Bacillus sp. NRRL B-14911
Length = 270
Score = 38.3 bits (85), Expect = 0.25
Identities = 21/70 (30%), Positives = 32/70 (45%)
Frame = +2
Query: 440 GSLLIDSSTIDXNVPQQIFPIALEKGLGFTDAPVSGRVMGCSKRYLAFMAGXRKKNFERS 619
G LI+ ++ + +++ +KG+ D PVSG G L MAG ER
Sbjct: 73 GQFLIEMTSGSPEMMKKVHAAYQQKGIPVLDGPVSGGTAGAENGTLTVMAGGDADVLERL 132
Query: 620 LPLLQVMGAN 649
P+L+ M N
Sbjct: 133 RPVLESMATN 142
>UniRef50_Q220G7 Cluster: 6-phosphogluconate dehydrogenase,
NAD-binding precursor; n=1; Rhodoferax ferrireducens
T118|Rep: 6-phosphogluconate dehydrogenase, NAD-binding
precursor - Rhodoferax ferrireducens (strain DSM 15236 /
ATCC BAA-621 / T118)
Length = 284
Score = 38.3 bits (85), Expect = 0.25
Identities = 24/76 (31%), Positives = 36/76 (47%)
Frame = +1
Query: 187 VAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGVTPANSIXXXXXXXXXXXS 366
+AFLG G +GG A K+G TV ++ S D ++A A+ GV A +
Sbjct: 4 IAFLGTGLLGGAFAEAAAKRGDTVTAWNRSPDKVHALAQFGVMAAANPAEAVQSAARVHL 63
Query: 367 ILTSNKVVLDVYLGQR 414
+L + VV +V R
Sbjct: 64 VLKDDAVVEEVLAAAR 79
>UniRef50_A3LTC4 Cluster: 3-hydroxyisobutyrate dehydrogenase-like
protein; n=6; Saccharomycetales|Rep:
3-hydroxyisobutyrate dehydrogenase-like protein - Pichia
stipitis (Yeast)
Length = 355
Score = 38.3 bits (85), Expect = 0.25
Identities = 26/70 (37%), Positives = 36/70 (51%), Gaps = 4/70 (5%)
Frame = +2
Query: 452 IDSSTIDXNVPQQIFPIALEK--GLGFTDAPVSGRVMGCSKRYLAFM-AGXRKKNFERSL 622
+DSSTID +++ ++ G F D PVSG V G K L+FM + ++ L
Sbjct: 130 LDSSTIDIPTSREVHEFVKKELPGADFIDTPVSGGVAGARKATLSFMLSRPNNESISADL 189
Query: 623 -PLLQVMGAN 649
LL MGAN
Sbjct: 190 RTLLNKMGAN 199
>UniRef50_UPI0001597301 Cluster: YfjR; n=1; Bacillus
amyloliquefaciens FZB42|Rep: YfjR - Bacillus
amyloliquefaciens FZB42
Length = 286
Score = 37.9 bits (84), Expect = 0.33
Identities = 21/74 (28%), Positives = 36/74 (48%)
Frame = +1
Query: 187 VAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGVTPANSIXXXXXXXXXXXS 366
+A +GLGNMG +A N++K G+++ Y+ +K+ G A + S
Sbjct: 3 IAIVGLGNMGRPIAENIMKAGYSLTVYNRTKEKAADLLDKGAEYAETPRQAAEHADIVLS 62
Query: 367 ILTSNKVVLDVYLG 408
+L+ + V DV G
Sbjct: 63 MLSDDDAVTDVTFG 76
Score = 36.3 bits (80), Expect = 1.0
Identities = 21/80 (26%), Positives = 37/80 (46%)
Frame = +2
Query: 401 TWGKDGVVAHAKKGSLLIDSSTIDXNVPQQIFPIALEKGLGFTDAPVSGRVMGCSKRYLA 580
T+G G++A + + I STI + +Q+ +G F APV GR K L
Sbjct: 74 TFGACGIIAGLSENGIHISMSTISTALSEQLSAAHSGRGQSFIAAPVLGRPDAAEKAELR 133
Query: 581 FMAGXRKKNFERSLPLLQVM 640
+ + +++ PLL ++
Sbjct: 134 IITAGPAEAKKKAEPLLNIL 153
>UniRef50_Q74D68 Cluster: 3-hydroxyisobutyrate dehydrogenase family
protein; n=7; Desulfuromonadales|Rep:
3-hydroxyisobutyrate dehydrogenase family protein -
Geobacter sulfurreducens
Length = 288
Score = 37.9 bits (84), Expect = 0.33
Identities = 20/47 (42%), Positives = 26/47 (55%)
Frame = +1
Query: 181 KNVAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGVTPA 321
+ V FLGLG +G MAANL+K + + YD A+ A G T A
Sbjct: 3 RKVGFLGLGTVGRHMAANLLKGNYELAVYDSDPAAVADLAALGATGA 49
Score = 34.7 bits (76), Expect = 3.1
Identities = 22/82 (26%), Positives = 33/82 (40%)
Frame = +2
Query: 404 WGKDGVVAHAKKGSLLIDSSTIDXNVPQQIFPIALEKGLGFTDAPVSGRVMGCSKRYLAF 583
+G DG+ A G++L+D T ++ A + + F DAPV G + L
Sbjct: 77 YGPDGIFAGIDPGTILVDMGTHSLTSTMEMADEAAKHRVMFLDAPVWGTKEHAANGLLTI 136
Query: 584 MAGXRKKNFERSLPLLQVMGAN 649
+AG R L G N
Sbjct: 137 LAGGDPSLVGRCRELFSFFGLN 158
>UniRef50_Q0F1Y7 Cluster: 6-phosphogluconate dehydrogenase,
NAD-binding protein; n=1; Mariprofundus ferrooxydans
PV-1|Rep: 6-phosphogluconate dehydrogenase, NAD-binding
protein - Mariprofundus ferrooxydans PV-1
Length = 289
Score = 37.9 bits (84), Expect = 0.33
Identities = 25/86 (29%), Positives = 39/86 (45%), Gaps = 1/86 (1%)
Frame = +1
Query: 181 KNVAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGVTPANSIXXXXXXXXXX 360
+N+ F+GLG MG MAAN++K+G + Y+ + + A G A+
Sbjct: 3 QNIGFIGLGIMGEAMAANILKQGHPLIVYNRTVEKAAALVDAGAMVADKPSLVADASDVI 62
Query: 361 XSILTSNKVVLDVYLGQR-WRCGSCE 435
+LT + V V G+ G CE
Sbjct: 63 ILMLTGEEAVDAVLFGEEGLLSGDCE 88
Score = 36.3 bits (80), Expect = 1.0
Identities = 23/91 (25%), Positives = 41/91 (45%)
Frame = +2
Query: 404 WGKDGVVAHAKKGSLLIDSSTIDXNVPQQIFPIALEKGLGFTDAPVSGRVMGCSKRYLAF 583
+G++G+++ +G +I+ ST+ ++ + G+ DAPVSG + L
Sbjct: 77 FGEEGLLSGDCEGKTVINMSTVPVECSKRWAKELADHGMTLIDAPVSGSKVPAQTGTLVI 136
Query: 584 MAGXRKKNFERSLPLLQVMGANSXTADRSGS 676
+AG + PLL MG +GS
Sbjct: 137 LAGGPEAAVRAQEPLLLSMGKKVIYCGPTGS 167
>UniRef50_A2C1U6 Cluster: 3-hydroxyisobutyrate dehydrogenase and
related beta-hydroxyacid dehydrogenases; n=2;
Prochlorococcus marinus|Rep: 3-hydroxyisobutyrate
dehydrogenase and related beta-hydroxyacid
dehydrogenases - Prochlorococcus marinus (strain NATL1A)
Length = 287
Score = 37.9 bits (84), Expect = 0.33
Identities = 24/80 (30%), Positives = 36/80 (45%)
Frame = +2
Query: 404 WGKDGVVAHAKKGSLLIDSSTIDXNVPQQIFPIALEKGLGFTDAPVSGRVMGCSKRYLAF 583
+G +GV K S +ID STI + I E+ + + D PVSG G L+
Sbjct: 71 FGDNGVSGSLKPNSFVIDFSTISPDKSISIHKRLGEQNIFYVDCPVSGGTEGAHNGSLSL 130
Query: 584 MAGXRKKNFERSLPLLQVMG 643
G +K+ + QV+G
Sbjct: 131 FIGASEKDCLSFENIFQVLG 150
>UniRef50_Q0C8I2 Cluster: Predicted protein; n=3;
Pezizomycotina|Rep: Predicted protein - Aspergillus
terreus (strain NIH 2624)
Length = 320
Score = 37.9 bits (84), Expect = 0.33
Identities = 28/74 (37%), Positives = 36/74 (48%), Gaps = 2/74 (2%)
Frame = +2
Query: 416 GVVAHAKKGSLLIDSSTIDX--NVPQQIFPIALEKGLGFTDAPVSGRVMGCSKRYLAFMA 589
GV + LLID STID ++ + F DAPVSG V+G K +AF
Sbjct: 92 GVCSTPLDTRLLIDCSTIDTATSLAVKAHITTHHASASFYDAPVSGGVLGAQKGAIAFFL 151
Query: 590 GXRKKNFERSLPLL 631
G K + +LPLL
Sbjct: 152 GCAKT--DPNLPLL 163
>UniRef50_Q9YFQ6 Cluster: L-lysine 6-dehydrogenase; n=1; Aeropyrum
pernix|Rep: L-lysine 6-dehydrogenase - Aeropyrum pernix
Length = 367
Score = 37.9 bits (84), Expect = 0.33
Identities = 19/42 (45%), Positives = 25/42 (59%)
Frame = +1
Query: 187 VAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGV 312
+A LGLG +G A NL +GF V G D S DA++ A G+
Sbjct: 4 IAVLGLGRVGLRAAYNLASRGFDVLGLDASNDAVSRARSLGL 45
>UniRef50_UPI0000E49FD0 Cluster: PREDICTED: similar to gamma
hydroxybutyrate dehydrogenase; n=3; Strongylocentrotus
purpuratus|Rep: PREDICTED: similar to gamma
hydroxybutyrate dehydrogenase - Strongylocentrotus
purpuratus
Length = 219
Score = 37.5 bits (83), Expect = 0.44
Identities = 22/95 (23%), Positives = 40/95 (42%)
Frame = +2
Query: 392 STCTWGKDGVVAHAKKGSLLIDSSTIDXNVPQQIFPIALEKGLGFTDAPVSGRVMGCSKR 571
S +G++GV+ +G +D ST+D + + F +APV G V +
Sbjct: 4 SMIVFGENGVLEGITEGKAFVDMSTVDIGTVTGVSEAVQARDGRFMEAPVCGSVQPAMEG 63
Query: 572 YLAFMAGXRKKNFERSLPLLQVMGANSXTADRSGS 676
L +A K+ ++ Q MG + +G+
Sbjct: 64 SLIIIAAGDKELYDECESCFQAMGKKAFYLSDTGN 98
>UniRef50_Q39KK8 Cluster: 6-phosphogluconate dehydrogenase,
NAD-binding; n=34; Bacteria|Rep: 6-phosphogluconate
dehydrogenase, NAD-binding - Burkholderia sp. (strain
383) (Burkholderia cepacia (strain ATCC 17760/ NCIB 9086
/ R18194))
Length = 289
Score = 37.5 bits (83), Expect = 0.44
Identities = 19/77 (24%), Positives = 37/77 (48%)
Frame = +2
Query: 413 DGVVAHAKKGSLLIDSSTIDXNVPQQIFPIALEKGLGFTDAPVSGRVMGCSKRYLAFMAG 592
D ++A A +G + ++ +T+ + + + +G+ + APV GR + L MAG
Sbjct: 75 DALLAQAPRGLIHVNMATVSVALAESLAHAHASRGIHYVAAPVMGRPDVAAAARLTIMAG 134
Query: 593 XRKKNFERSLPLLQVMG 643
+ +R PL +G
Sbjct: 135 GPAEAIDRVQPLFDAIG 151
Score = 36.7 bits (81), Expect = 0.77
Identities = 20/52 (38%), Positives = 31/52 (59%), Gaps = 4/52 (7%)
Frame = +1
Query: 184 NVAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGV----TPANS 327
++ F+GLG MG +A NL+K G TVR ++ S++ A G TPA++
Sbjct: 2 DLGFIGLGEMGQAIATNLLKAGHTVRVWNRSRERAEPLAAIGAQIVDTPADA 53
>UniRef50_Q121N3 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=19;
Burkholderiales|Rep: 3-hydroxyisobutyrate dehydrogenase
- Polaromonas sp. (strain JS666 / ATCC BAA-500)
Length = 298
Score = 37.5 bits (83), Expect = 0.44
Identities = 20/79 (25%), Positives = 36/79 (45%)
Frame = +2
Query: 404 WGKDGVVAHAKKGSLLIDSSTIDXNVPQQIFPIALEKGLGFTDAPVSGRVMGCSKRYLAF 583
W + GV + K GS+ + ST+D + G+ + DAP+SG + +
Sbjct: 78 WSEQGVASAMKSGSVFVMCSTVDPQWSIATEARLDKLGIHYVDAPISGGAAKAAAGQMTV 137
Query: 584 MAGXRKKNFERSLPLLQVM 640
M+ R +E++ +L M
Sbjct: 138 MSSARPAAYEKAGDVLAAM 156
>UniRef50_A3PSD9 Cluster: 6-phosphogluconate dehydrogenase,
decarboxylating; n=11; Bacteria|Rep: 6-phosphogluconate
dehydrogenase, decarboxylating - Mycobacterium sp.
(strain JLS)
Length = 297
Score = 37.5 bits (83), Expect = 0.44
Identities = 23/76 (30%), Positives = 33/76 (43%)
Frame = +2
Query: 437 KGSLLIDSSTIDXNVPQQIFPIALEKGLGFTDAPVSGRVMGCSKRYLAFMAGXRKKNFER 616
+G L+ID + KG+GF DA VSG V G ++ Y M G + ER
Sbjct: 77 EGDLVIDGGNSRFTEDAPHAELLKAKGIGFIDAGVSGGVWGLAEGY-GLMVGGDDADIER 135
Query: 617 SLPLLQVMGANSXTAD 664
+P+ + AD
Sbjct: 136 VMPIFDTLRPPGDRAD 151
>UniRef50_A1GFG2 Cluster: 6-phosphogluconate dehydrogenase,
NAD-binding; n=1; Salinispora arenicola CNS205|Rep:
6-phosphogluconate dehydrogenase, NAD-binding -
Salinispora arenicola CNS205
Length = 315
Score = 37.5 bits (83), Expect = 0.44
Identities = 21/76 (27%), Positives = 34/76 (44%)
Frame = +2
Query: 416 GVVAHAKKGSLLIDSSTIDXNVPQQIFPIALEKGLGFTDAPVSGRVMGCSKRYLAFMAGX 595
G + G+L +D ST+ +++ ++G F DAPV G L F+AG
Sbjct: 81 GALTSLAPGTLAVDCSTVTPTFSRELAACCAQRGAEFLDAPVLGSRPQADAGTLIFLAGG 140
Query: 596 RKKNFERSLPLLQVMG 643
R P+L+ +G
Sbjct: 141 DLAVLHRIEPVLRQVG 156
>UniRef50_A6RMW8 Cluster: Putative uncharacterized protein; n=2;
Sclerotiniaceae|Rep: Putative uncharacterized protein -
Botryotinia fuckeliana B05.10
Length = 446
Score = 37.5 bits (83), Expect = 0.44
Identities = 25/57 (43%), Positives = 34/57 (59%), Gaps = 4/57 (7%)
Frame = +1
Query: 169 SNTDKN-VAFLGLGNMGGFMAANLVKKGFTVRG---YDPSKDALNAAAKNGVTPANS 327
S++DK VAF+GLG MG MA NL+K F+V G Y+P+ + +A N T S
Sbjct: 2 SSSDKPAVAFIGLGAMGMGMATNLLKT-FSVTGFDVYEPTLEKFRSAGGNTATTPRS 57
>UniRef50_A5FTT0 Cluster: 6-phosphogluconate dehydrogenase,
NAD-binding; n=3; Alphaproteobacteria|Rep:
6-phosphogluconate dehydrogenase, NAD-binding -
Acidiphilium cryptum (strain JF-5)
Length = 305
Score = 37.1 bits (82), Expect = 0.58
Identities = 28/84 (33%), Positives = 38/84 (45%), Gaps = 1/84 (1%)
Frame = +1
Query: 181 KNVAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKN-GVTPANSIXXXXXXXXX 357
+ VAF+GLGNMG MAA LV G V G D + A A+ G T A
Sbjct: 3 QRVAFIGLGNMGWPMAARLVGGGCEVTGCDAVEGRAEAFAREVGGTAAADADAAARGAEF 62
Query: 358 XXSILTSNKVVLDVYLGQRWRCGS 429
++L ++ +V V R G+
Sbjct: 63 IVTMLPNSALVESVVAAMRPSLGA 86
>UniRef50_A1ZWM5 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=1;
Microscilla marina ATCC 23134|Rep: 3-hydroxyisobutyrate
dehydrogenase - Microscilla marina ATCC 23134
Length = 295
Score = 37.1 bits (82), Expect = 0.58
Identities = 25/75 (33%), Positives = 35/75 (46%)
Frame = +1
Query: 187 VAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGVTPANSIXXXXXXXXXXXS 366
+AF+GLG MG MA+NL+K + Y+ S A G A++ S
Sbjct: 3 IAFIGLGIMGSRMASNLLKHKVDLTVYNRSLAATTPLVALGAKVAHTTTEAVKEADIVFS 62
Query: 367 ILTSNKVVLDVYLGQ 411
+L S +VV V GQ
Sbjct: 63 MLASPQVVKAVAYGQ 77
Score = 35.1 bits (77), Expect = 2.3
Identities = 21/80 (26%), Positives = 36/80 (45%)
Frame = +2
Query: 404 WGKDGVVAHAKKGSLLIDSSTIDXNVPQQIFPIALEKGLGFTDAPVSGRVMGCSKRYLAF 583
+G+ G ++ K +L ID STI A + + F +APV+G L F
Sbjct: 75 YGQTGFLSKMKSKALWIDCSTISPAFALASAQEASKHEVVFVEAPVAGTKSHAENAELVF 134
Query: 584 MAGXRKKNFERSLPLLQVMG 643
+ G ++ P +++MG
Sbjct: 135 LVGGGTTAIAQATPYMEMMG 154
>UniRef50_A1UJF2 Cluster: 6-phosphogluconate dehydrogenase,
NAD-binding; n=6; Actinomycetales|Rep:
6-phosphogluconate dehydrogenase, NAD-binding -
Mycobacterium sp. (strain KMS)
Length = 272
Score = 37.1 bits (82), Expect = 0.58
Identities = 20/75 (26%), Positives = 37/75 (49%)
Frame = +2
Query: 404 WGKDGVVAHAKKGSLLIDSSTIDXNVPQQIFPIALEKGLGFTDAPVSGRVMGCSKRYLAF 583
+G GV+A G+++ ST+ + ++I A + + DAPVSG + L
Sbjct: 75 YGDTGVLAGLAPGAMIAIHSTVHPDTCREIAEKAAAQNVSVIDAPVSGGAPAVEQGKLLV 134
Query: 584 MAGXRKKNFERSLPL 628
M G + + E++ P+
Sbjct: 135 MVGGEEADVEKARPV 149
>UniRef50_A0R1N4 Cluster: 6-phosphogluconate dehydrogenase,
NAD-binding; n=3; Mycobacterium|Rep: 6-phosphogluconate
dehydrogenase, NAD-binding - Mycobacterium smegmatis
(strain ATCC 700084 / mc(2)155)
Length = 272
Score = 37.1 bits (82), Expect = 0.58
Identities = 22/74 (29%), Positives = 34/74 (45%)
Frame = +2
Query: 407 GKDGVVAHAKKGSLLIDSSTIDXNVPQQIFPIALEKGLGFTDAPVSGRVMGCSKRYLAFM 586
G+ GV+A G ++ ST+ + +I EKG+ DAPVSG L M
Sbjct: 76 GETGVLAGLAPGGIIAIHSTVHPDTCTEIAEQVAEKGISLIDAPVSGGEPAAKAGTLLVM 135
Query: 587 AGXRKKNFERSLPL 628
AG + ++ P+
Sbjct: 136 AGGDEDIVDKVRPV 149
>UniRef50_Q9LM23 Cluster: Fructose-bisphosphate aldolase; n=2;
Arabidopsis thaliana|Rep: Fructose-bisphosphate aldolase
- Arabidopsis thaliana (Mouse-ear cress)
Length = 1486
Score = 37.1 bits (82), Expect = 0.58
Identities = 17/30 (56%), Positives = 22/30 (73%)
Frame = +1
Query: 187 VAFLGLGNMGGFMAANLVKKGFTVRGYDPS 276
+ F+GLG MG MAA+L+K F+V GYD S
Sbjct: 348 IGFIGLGAMGFGMAAHLLKSNFSVCGYDIS 377
>UniRef50_Q656T5 Cluster: Oxidoreductase-like; n=3; Oryza
sativa|Rep: Oxidoreductase-like - Oryza sativa subsp.
japonica (Rice)
Length = 341
Score = 36.7 bits (81), Expect = 0.77
Identities = 23/79 (29%), Positives = 31/79 (39%)
Frame = +2
Query: 407 GKDGVVAHAKKGSLLIDSSTIDXNVPQQIFPIALEKGLGFTDAPVSGRVMGCSKRYLAFM 586
G +G G +D ST+D + I G F +APVSG L F+
Sbjct: 126 GANGAAQGMAPGKGYVDVSTVDAATSKLIGKHITSTGASFLEAPVSGSKKPAEDGLLIFL 185
Query: 587 AGXRKKNFERSLPLLQVMG 643
+ + R LL VMG
Sbjct: 186 TAGDESLYNRVASLLDVMG 204
>UniRef50_Q988C8 Cluster: 3-hydroxybutyryl-coA dehydrogenase; n=1;
Mesorhizobium loti|Rep: 3-hydroxybutyryl-coA
dehydrogenase - Rhizobium loti (Mesorhizobium loti)
Length = 309
Score = 36.3 bits (80), Expect = 1.0
Identities = 17/39 (43%), Positives = 23/39 (58%)
Frame = +1
Query: 181 KNVAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAA 297
+N+A +GLG MG MAA L + G V YD + A+ A
Sbjct: 3 RNIAIIGLGTMGPGMAARLARGGLQVVAYDVAPAAIERA 41
>UniRef50_Q3J9H5 Cluster: 6-phosphogluconate dehydrogenase,
decarboxylating; n=2; Bacteria|Rep: 6-phosphogluconate
dehydrogenase, decarboxylating - Nitrosococcus oceani
(strain ATCC 19707 / NCIMB 11848)
Length = 481
Score = 36.3 bits (80), Expect = 1.0
Identities = 17/41 (41%), Positives = 24/41 (58%), Gaps = 2/41 (4%)
Frame = +1
Query: 169 SNTDKNVAFLGLGNMGGFMAANLVKKGFTVRGYD--PSKDA 285
S T ++ +GLG MG + N+ ++GF V GYD P K A
Sbjct: 6 SPTSADIGIIGLGVMGANLGLNIAEQGFNVAGYDRNPEKGA 46
>UniRef50_Q1YFU0 Cluster: Posibble methylase involved in
ubiquinone/menaquinone biosynthesis; n=1; Aurantimonas
sp. SI85-9A1|Rep: Posibble methylase involved in
ubiquinone/menaquinone biosynthesis - Aurantimonas sp.
SI85-9A1
Length = 241
Score = 36.3 bits (80), Expect = 1.0
Identities = 20/42 (47%), Positives = 28/42 (66%)
Frame = +1
Query: 196 LGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGVTPA 321
L +G G +A +LVK+GF V G DPS+ A+ AAA++ V A
Sbjct: 37 LDIGCGRGALARSLVKRGFAVTGIDPSEAAI-AAARDSVPEA 77
>UniRef50_A6F020 Cluster: Putative uncharacterized protein; n=1;
Marinobacter algicola DG893|Rep: Putative
uncharacterized protein - Marinobacter algicola DG893
Length = 286
Score = 36.3 bits (80), Expect = 1.0
Identities = 17/48 (35%), Positives = 29/48 (60%)
Frame = +1
Query: 187 VAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGVTPANSI 330
V+ +G+G+MG +A ++ KG V YD S++ + AKNG+ S+
Sbjct: 3 VSIIGVGDMGRDIAVHVRDKGHDVIAYDISEERRSDVAKNGIKVVESL 50
>UniRef50_A1WM48 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=1;
Verminephrobacter eiseniae EF01-2|Rep:
3-hydroxyisobutyrate dehydrogenase - Verminephrobacter
eiseniae (strain EF01-2)
Length = 301
Score = 36.3 bits (80), Expect = 1.0
Identities = 19/45 (42%), Positives = 24/45 (53%)
Frame = +1
Query: 193 FLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGVTPANS 327
F+GLGNMGG M L+ G TV +D AL A +G +S
Sbjct: 9 FIGLGNMGGPMVKRLLHAGHTVLVFDRDAAALARAVADGAQARSS 53
Score = 35.9 bits (79), Expect = 1.3
Identities = 24/95 (25%), Positives = 44/95 (46%)
Frame = +2
Query: 359 SFPY*PAIKSCSTCTWGKDGVVAHAKKGSLLIDSSTIDXNVPQQIFPIALEKGLGFTDAP 538
S P PA++ + +DG++ K+ ++D STI +G+ + D+P
Sbjct: 67 SLPDGPAVQHVISA---QDGLL-QGKRVKCVVDLSTIGPRAAVAASQALGARGIAYVDSP 122
Query: 539 VSGRVMGCSKRYLAFMAGXRKKNFERSLPLLQVMG 643
VSG + G + LA M + ++ P+L+ G
Sbjct: 123 VSGGIGGAERGTLAVMTACPQPLYDELAPVLKNFG 157
>UniRef50_A0JRK4 Cluster: 6-phosphogluconate dehydrogenase,
NAD-binding precursor; n=3; Actinomycetales|Rep:
6-phosphogluconate dehydrogenase, NAD-binding precursor
- Arthrobacter sp. (strain FB24)
Length = 299
Score = 36.3 bits (80), Expect = 1.0
Identities = 24/92 (26%), Positives = 48/92 (52%), Gaps = 2/92 (2%)
Frame = +2
Query: 404 WGKDGVVAHAKKGSLLIDSSTIDXN-VPQQIFPIALEKGLGFTDAPVSGRVMGCSKRYLA 580
+G +GV + K G+++I ST+ + +P + +A E G+ DAP+SG + L
Sbjct: 78 FGANGVASVLKPGAVVILGSTVGTDAIPATVDRLA-EYGVELVDAPLSGGPKRAGEGDLL 136
Query: 581 FMAGXRKKNFERSLPLLQVMGAN-SXTADRSG 673
+ G + E++ P L+++ + + D+ G
Sbjct: 137 IVVGASPEAQEKARPALELLASTLTVVGDKPG 168
>UniRef50_Q21AH6 Cluster: 6-phosphogluconate dehydrogenase,
NAD-binding; n=3; Bacteria|Rep: 6-phosphogluconate
dehydrogenase, NAD-binding - Rhodopseudomonas palustris
(strain BisB18)
Length = 292
Score = 35.9 bits (79), Expect = 1.3
Identities = 18/53 (33%), Positives = 28/53 (52%)
Frame = +1
Query: 169 SNTDKNVAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGVTPANS 327
S + N+ +GLG MGG +A L +++ YD SK A+ +G + A S
Sbjct: 2 SRSIDNIGIIGLGAMGGAVATRLTSGPWSLAVYDLSKAAIERLVSHGASAAAS 54
>UniRef50_Q1INE9 Cluster: 6-phosphogluconate dehydrogenase,
NAD-binding; n=1; Acidobacteria bacterium Ellin345|Rep:
6-phosphogluconate dehydrogenase, NAD-binding -
Acidobacteria bacterium (strain Ellin345)
Length = 313
Score = 35.9 bits (79), Expect = 1.3
Identities = 20/48 (41%), Positives = 25/48 (52%)
Frame = +1
Query: 187 VAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGVTPANSI 330
V FLGLGNMG MAANL+ G V ++ + + GV A I
Sbjct: 25 VGFLGLGNMGEPMAANLIAAGHQVTVWNRTAAKAEPLKERGVKVATEI 72
>UniRef50_Q0KC92 Cluster: 3-Hydroxyisobutyrate dehydrogenase; n=1;
Ralstonia eutropha H16|Rep: 3-Hydroxyisobutyrate
dehydrogenase - Ralstonia eutropha (strain ATCC 17699 /
H16 / DSM 428 / Stanier 337)(Cupriavidus necator (strain
ATCC 17699 / H16 / DSM 428 / Stanier337))
Length = 305
Score = 35.9 bits (79), Expect = 1.3
Identities = 22/78 (28%), Positives = 36/78 (46%), Gaps = 1/78 (1%)
Frame = +2
Query: 416 GVVAHAKKGSLLIDSSTIDXNVPQQIFPIALEKGLGFTDAPVSGRV-MGCSKRYLAFMAG 592
GV A + +D ST+ + ++ +G F APVSG V + S + F++G
Sbjct: 91 GVAGAATADKVFVDMSTVSPDASAEVAAALARRGAAFLRAPVSGTVSLAASAQLSCFVSG 150
Query: 593 XRKKNFERSLPLLQVMGA 646
R F+ P+L + A
Sbjct: 151 PRPA-FDAVQPVLACLTA 167
>UniRef50_A4ES45 Cluster: Methyltransferase type 11; n=1;
Roseobacter sp. SK209-2-6|Rep: Methyltransferase type 11
- Roseobacter sp. SK209-2-6
Length = 195
Score = 35.9 bits (79), Expect = 1.3
Identities = 18/40 (45%), Positives = 24/40 (60%)
Frame = +1
Query: 196 LGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGVT 315
L LG G AA L ++GFTV DP+ + + AA K GV+
Sbjct: 44 LDLGCGPGIQAAELKQRGFTVEAIDPTPEFVMAAEKRGVS 83
>UniRef50_A4ARS6 Cluster: 6-phosphogluconate dehydrogenase,
NAD-binding:D-isomer specific 2- hydroxyacid
dehydrogenase, NAD-binding protein; n=2;
Flavobacteriales|Rep: 6-phosphogluconate dehydrogenase,
NAD-binding:D-isomer specific 2- hydroxyacid
dehydrogenase, NAD-binding protein - Flavobacteriales
bacterium HTCC2170
Length = 309
Score = 35.9 bits (79), Expect = 1.3
Identities = 15/39 (38%), Positives = 24/39 (61%)
Frame = +1
Query: 163 YSSNTDKNVAFLGLGNMGGFMAANLVKKGFTVRGYDPSK 279
Y D + +GLG +G +A +L++ GFTV+G+ SK
Sbjct: 128 YQRIEDLTIGIMGLGALGKVLAKDLIRFGFTVQGWSGSK 166
>UniRef50_Q0URA2 Cluster: Putative uncharacterized protein; n=1;
Phaeosphaeria nodorum|Rep: Putative uncharacterized
protein - Phaeosphaeria nodorum (Septoria nodorum)
Length = 325
Score = 35.9 bits (79), Expect = 1.3
Identities = 27/65 (41%), Positives = 31/65 (47%), Gaps = 1/65 (1%)
Frame = +2
Query: 452 IDSSTIDXNVPQQIFPIALEKGLGFTDAPVSGRVMGCSKRYLAFMAGXRKKN-FERSLPL 628
I++STI V + + L F DAPVSG MG LAFMAG K F R
Sbjct: 116 IETSTI-LEVAKATSSSKAAENLTFVDAPVSGGPMGAQDGTLAFMAGANNKAIFPRVKGY 174
Query: 629 LQVMG 643
L MG
Sbjct: 175 LSHMG 179
>UniRef50_Q944B6 Cluster: Arogenate dehydrogenase 1, chloroplast
precursor; n=1; Arabidopsis thaliana|Rep: Arogenate
dehydrogenase 1, chloroplast precursor - Arabidopsis
thaliana (Mouse-ear cress)
Length = 640
Score = 35.9 bits (79), Expect = 1.3
Identities = 18/43 (41%), Positives = 25/43 (58%)
Frame = +1
Query: 187 VAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGVT 315
+ +G GN G F+ +VK+G TV Y S D + AAK GV+
Sbjct: 367 IGIVGFGNFGQFLGKTMVKQGHTVLAYSRS-DYTDEAAKLGVS 408
>UniRef50_Q8PK98 Cluster: 3-hydroxyisobutirate dehydrogenase; n=3;
Proteobacteria|Rep: 3-hydroxyisobutirate dehydrogenase -
Xanthomonas axonopodis pv. citri
Length = 300
Score = 35.5 bits (78), Expect = 1.8
Identities = 19/66 (28%), Positives = 30/66 (45%)
Frame = +2
Query: 446 LLIDSSTIDXNVPQQIFPIALEKGLGFTDAPVSGRVMGCSKRYLAFMAGXRKKNFERSLP 625
L++D ST ++ + + F APVSG ++ L MA +ER+ P
Sbjct: 91 LVVDLSTTGAQTTSEVGHLLERADVSFLSAPVSGGTAAAAQGVLTVMAAGPLAAYERARP 150
Query: 626 LLQVMG 643
LL +G
Sbjct: 151 LLDAVG 156
>UniRef50_Q5PAV2 Cluster: 3-demethylubiquinone-9
3-methyltransferase; n=1; Anaplasma marginale str. St.
Maries|Rep: 3-demethylubiquinone-9 3-methyltransferase -
Anaplasma marginale (strain St. Maries)
Length = 225
Score = 35.5 bits (78), Expect = 1.8
Identities = 22/69 (31%), Positives = 36/69 (52%)
Frame = +1
Query: 94 TNSKWPRAQY*STQCLYTAARRAYSSNTDKNVAFLGLGNMGGFMAANLVKKGFTVRGYDP 273
T + P Y ++ CL + SS + L +G GG A ++V+ GF+V G DP
Sbjct: 10 TLTSQPTVIYWTSACLNSLQ----SSQRRGQRSLLDIGCGGGIFAESMVRLGFSVTGVDP 65
Query: 274 SKDALNAAA 300
S+ ++ AA+
Sbjct: 66 SQASIEAAS 74
>UniRef50_Q0RMX6 Cluster: Putative reductase; n=1; Frankia alni
ACN14a|Rep: Putative reductase - Frankia alni (strain
ACN14a)
Length = 262
Score = 35.5 bits (78), Expect = 1.8
Identities = 21/77 (27%), Positives = 36/77 (46%)
Frame = +2
Query: 401 TWGKDGVVAHAKKGSLLIDSSTIDXNVPQQIFPIALEKGLGFTDAPVSGRVMGCSKRYLA 580
T G G++AHA GS+++ +T+ +++ A + + DAP+SG L
Sbjct: 64 TGGPGGLLAHATPGSVVVQHATVATEAIRRLAADAAAQDVTVLDAPISGTSATILAGRLT 123
Query: 581 FMAGXRKKNFERSLPLL 631
+ G +R PLL
Sbjct: 124 VLIGGAAAAADRVEPLL 140
>UniRef50_A6W129 Cluster: 6-phosphogluconate dehydrogenase,
decarboxylating; n=8; Gammaproteobacteria|Rep:
6-phosphogluconate dehydrogenase, decarboxylating -
Marinomonas sp. MWYL1
Length = 507
Score = 35.5 bits (78), Expect = 1.8
Identities = 15/34 (44%), Positives = 22/34 (64%)
Frame = +1
Query: 169 SNTDKNVAFLGLGNMGGFMAANLVKKGFTVRGYD 270
+N + N+ F+GLG MG +A NL G+ V G+D
Sbjct: 4 TNQNCNIGFVGLGVMGKNLALNLADHGYRVAGFD 37
>UniRef50_Q019Z7 Cluster: Oxidoreductase-like; n=1; Ostreococcus
tauri|Rep: Oxidoreductase-like - Ostreococcus tauri
Length = 325
Score = 35.5 bits (78), Expect = 1.8
Identities = 25/79 (31%), Positives = 33/79 (41%), Gaps = 5/79 (6%)
Frame = +2
Query: 422 VAHAKKGSL-----LIDSSTIDXNVPQQIFPIALEKGLGFTDAPVSGRVMGCSKRYLAFM 586
VAHA K L +D ST+D + I + G F +APVSG L F+
Sbjct: 115 VAHAAKEGLSSGKGYVDVSTVDAGTSRAIAEVVRSTGAEFLEAPVSGSKKPAEDGALIFL 174
Query: 587 AGXRKKNFERSLPLLQVMG 643
+ + R L VMG
Sbjct: 175 CAGDEGLYTRCTDPLDVMG 193
Score = 33.1 bits (72), Expect = 9.4
Identities = 18/53 (33%), Positives = 28/53 (52%)
Frame = +1
Query: 169 SNTDKNVAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGVTPANS 327
++T +AFLG G MG MA NL+ G V ++ ++ A + G T A +
Sbjct: 39 TSTPMKLAFLGCGIMGVPMAKNLIAAGHDVTVWNRTESATKPVVEAGATLAKT 91
>UniRef50_A7SFT5 Cluster: Predicted protein; n=1; Nematostella
vectensis|Rep: Predicted protein - Nematostella
vectensis
Length = 226
Score = 35.5 bits (78), Expect = 1.8
Identities = 17/52 (32%), Positives = 26/52 (50%), Gaps = 1/52 (1%)
Frame = +1
Query: 712 WASPEW-LPLNA*TWALKWDSNXKVLLEXPEKLIGLPPWSTEGXTVXFPDWV 864
W +P W +P + W + W + +V+ P PPW+T G T+ P WV
Sbjct: 134 WHTPPWVIPWHRPPWVIPWHTPPRVI---PWHT---PPWTTMGYTIHTPPWV 179
>UniRef50_Q2LGT9 Cluster: 6-phosphogluconate dehydrogenase; n=6;
Halobacteriaceae|Rep: 6-phosphogluconate dehydrogenase -
Haloquadratum walsbyi
Length = 306
Score = 35.5 bits (78), Expect = 1.8
Identities = 17/45 (37%), Positives = 25/45 (55%)
Frame = +1
Query: 196 LGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGVTPANSI 330
+GLG MG + LV G + +D +A+ AA G TPA+S+
Sbjct: 6 VGLGRMGQIVVDRLVTAGHDIVAFDLDAEAVATAADIGATPADSL 50
>UniRef50_Q1N6E5 Cluster: Erythronate-4-phosphate dehydrogenase;
n=1; Oceanobacter sp. RED65|Rep: Erythronate-4-phosphate
dehydrogenase - Oceanobacter sp. RED65
Length = 377
Score = 35.1 bits (77), Expect = 2.3
Identities = 15/53 (28%), Positives = 26/53 (49%)
Frame = +1
Query: 136 CLYTAARRAYSSNTDKNVAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNA 294
C+ + S D +V +G GN+GG + L + G YDP+ + L++
Sbjct: 103 CMLVISEMKQRSIRDMSVGIVGAGNVGGMLLETLTQVGVEAIAYDPNIEGLDS 155
>UniRef50_A6VZU5 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase NAD-binding; n=1; Marinomonas sp.
MWYL1|Rep: D-isomer specific 2-hydroxyacid dehydrogenase
NAD-binding - Marinomonas sp. MWYL1
Length = 310
Score = 35.1 bits (77), Expect = 2.3
Identities = 14/37 (37%), Positives = 24/37 (64%)
Frame = +1
Query: 178 DKNVAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDAL 288
D + FLGLG +GG++++ L G++V G+ +K L
Sbjct: 134 DIRIGFLGLGELGGYVSSQLAAFGYSVYGWSRTKKFL 170
>UniRef50_A6VLT0 Cluster: 2-hydroxy-3-oxopropionate reductase; n=2;
Pasteurellaceae|Rep: 2-hydroxy-3-oxopropionate reductase
- Actinobacillus succinogenes 130Z
Length = 289
Score = 35.1 bits (77), Expect = 2.3
Identities = 21/69 (30%), Positives = 34/69 (49%)
Frame = +2
Query: 422 VAHAKKGSLLIDSSTIDXNVPQQIFPIALEKGLGFTDAPVSGRVMGCSKRYLAFMAGXRK 601
V A KG L+++ ST+ QQ+ + + G F +APVSG L +A ++
Sbjct: 84 VLTALKGKLVVNMSTVSPTQNQQLEFLLAKHGAEFIEAPVSGSSKVAEAGKLLVLAAGKE 143
Query: 602 KNFERSLPL 628
+ E+ PL
Sbjct: 144 EIVEQLKPL 152
>UniRef50_A0RU56 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=1;
Cenarchaeum symbiosum|Rep: 3-hydroxyisobutyrate
dehydrogenase - Cenarchaeum symbiosum
Length = 282
Score = 35.1 bits (77), Expect = 2.3
Identities = 24/92 (26%), Positives = 38/92 (41%)
Frame = +2
Query: 401 TWGKDGVVAHAKKGSLLIDSSTIDXNVPQQIFPIALEKGLGFTDAPVSGRVMGCSKRYLA 580
++G++G+ A K +L D STI+ I + G+ DAPV G + L
Sbjct: 65 SFGENGIAQGAHKDLVLCDMSTINPEGAVSISKKLADAGIRMVDAPVMGGPGAAMRGELV 124
Query: 581 FMAGXRKKNFERSLPLLQVMGANSXTADRSGS 676
MA K +E +L + SG+
Sbjct: 125 IMASGDKGAYEERRGILGAVSRKMFYLGGSGT 156
>UniRef50_UPI00015B50D2 Cluster: PREDICTED: similar to conserved
hypothetical protein; n=1; Nasonia vitripennis|Rep:
PREDICTED: similar to conserved hypothetical protein -
Nasonia vitripennis
Length = 1016
Score = 34.7 bits (76), Expect = 3.1
Identities = 16/46 (34%), Positives = 26/46 (56%), Gaps = 1/46 (2%)
Frame = +2
Query: 86 KKKQIQNG-RAHNIKALSVCTQPPDGRIVLTPTRMWLSSASETWED 220
K +Q++ G R ++ + SV QPPD +TP++ SE+W D
Sbjct: 605 KPRQLKAGKRKLSVTSASVSIQPPDSEKAMTPSKKMQVDLSESWND 650
>UniRef50_UPI0000E46E06 Cluster: PREDICTED: similar to MGC107852
protein; n=1; Strongylocentrotus purpuratus|Rep:
PREDICTED: similar to MGC107852 protein -
Strongylocentrotus purpuratus
Length = 432
Score = 34.7 bits (76), Expect = 3.1
Identities = 16/49 (32%), Positives = 28/49 (57%)
Frame = +1
Query: 175 TDKNVAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGVTPA 321
T+K + F+GLG MG MA NL+K G V ++ + + + + + P+
Sbjct: 360 TEKKIGFIGLGLMGTGMAMNLIKAGHKVTVWNRTSEKVRLYSPITIFPS 408
Score = 34.3 bits (75), Expect = 4.1
Identities = 15/28 (53%), Positives = 19/28 (67%)
Frame = +1
Query: 175 TDKNVAFLGLGNMGGFMAANLVKKGFTV 258
T+K + F+GLG MG MA NL+K G V
Sbjct: 277 TEKRIGFIGLGLMGTGMAMNLIKAGHKV 304
>UniRef50_Q9RU02 Cluster: 6-phosphogluconate dehydrogenase; n=24;
Bacteria|Rep: 6-phosphogluconate dehydrogenase -
Deinococcus radiodurans
Length = 368
Score = 34.7 bits (76), Expect = 3.1
Identities = 16/42 (38%), Positives = 23/42 (54%)
Frame = +1
Query: 187 VAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGV 312
+ +GLG MGG M L G V G+D S++A++ GV
Sbjct: 5 IGMIGLGKMGGNMVIRLKNGGQDVVGFDRSQEAIDHLVSQGV 46
Score = 34.3 bits (75), Expect = 4.1
Identities = 21/76 (27%), Positives = 32/76 (42%)
Frame = +2
Query: 413 DGVVAHAKKGSLLIDSSTIDXNVPQQIFPIALEKGLGFTDAPVSGRVMGCSKRYLAFMAG 592
D + G ++ID + + Q+ KGL F D SG V G ++ Y M G
Sbjct: 85 DDLAGRLSAGDVIIDGGNSNFHDTQRRGEALAAKGLHFVDVGTSGGVWGITEGY-GMMVG 143
Query: 593 XRKKNFERSLPLLQVM 640
+ ER P L+ +
Sbjct: 144 GPDEGVERIRPALEAL 159
>UniRef50_Q9I1R8 Cluster: Probable dehydrogenase; n=7; Pseudomonas
aeruginosa|Rep: Probable dehydrogenase - Pseudomonas
aeruginosa
Length = 291
Score = 34.7 bits (76), Expect = 3.1
Identities = 20/76 (26%), Positives = 35/76 (46%)
Frame = +2
Query: 416 GVVAHAKKGSLLIDSSTIDXNVPQQIFPIALEKGLGFTDAPVSGRVMGCSKRYLAFMAGX 595
G + A+ G + + ST+ + + + +GL F APV GR L + G
Sbjct: 77 GALERARPGLIHLSMSTLSLDCVEALDQAHQRQGLAFVAAPVFGRTDVAEAGKLNIVVGG 136
Query: 596 RKKNFERSLPLLQVMG 643
++ E+ LL++MG
Sbjct: 137 PEEAIEQVKALLEIMG 152
>UniRef50_Q2S7E0 Cluster: Phosphoglycerate dehydrogenase and related
dehydrogenase; n=1; Hahella chejuensis KCTC 2396|Rep:
Phosphoglycerate dehydrogenase and related dehydrogenase
- Hahella chejuensis (strain KCTC 2396)
Length = 296
Score = 34.7 bits (76), Expect = 3.1
Identities = 16/46 (34%), Positives = 24/46 (52%)
Frame = +1
Query: 163 YSSNTDKNVAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAA 300
Y +N + V LGLG++GG +A L G+ G+ S L+ A
Sbjct: 128 YRANRETRVGVLGLGSLGGAVAQRLHNLGYPTSGWSRSPKTLSGVA 173
>UniRef50_Q20XN2 Cluster: 6-phosphogluconate dehydrogenase,
NAD-binding; n=1; Rhodopseudomonas palustris BisB18|Rep:
6-phosphogluconate dehydrogenase, NAD-binding -
Rhodopseudomonas palustris (strain BisB18)
Length = 365
Score = 34.7 bits (76), Expect = 3.1
Identities = 28/104 (26%), Positives = 44/104 (42%)
Frame = +2
Query: 332 LQPLMESTWSFPY*PAIKSCSTCTWGKDGVVAHAKKGSLLIDSSTIDXNVPQQIFPIALE 511
L L E F P ++ + G G+V K G++ I STI + +++ E
Sbjct: 70 LADLAECDVVFSSLPDDEAVTAVAAGAGGLVKIMKAGAVHISMSTISPTMSRRLAAWHGE 129
Query: 512 KGLGFTDAPVSGRVMGCSKRYLAFMAGXRKKNFERSLPLLQVMG 643
G G+ APV G R L +A +++ PLL +G
Sbjct: 130 CGQGYVAAPVLGNPDLARARTLFILAAGPDAAMQKARPLLDRLG 173
>UniRef50_A5CN67 Cluster: Putative beta-hydroxyacid dehydrogenase;
n=1; Clavibacter michiganensis subsp. michiganensis
NCPPB 382|Rep: Putative beta-hydroxyacid dehydrogenase -
Clavibacter michiganensis subsp. michiganensis (strain
NCPPB 382)
Length = 291
Score = 34.7 bits (76), Expect = 3.1
Identities = 18/76 (23%), Positives = 37/76 (48%)
Frame = +2
Query: 434 KKGSLLIDSSTIDXNVPQQIFPIALEKGLGFTDAPVSGRVMGCSKRYLAFMAGXRKKNFE 613
+ G++++ SST+ ++I +A E + F DAPV G + L + + +
Sbjct: 80 RPGAVVLQSSTVGVEGTRRIAALAAEHAVRFVDAPVLGTRGPAEQGLLVHLVSGSEDDLA 139
Query: 614 RSLPLLQVMGANSXTA 661
+ P+L+ G+ + A
Sbjct: 140 VARPVLEATGSRTVVA 155
>UniRef50_A4XCN7 Cluster: Methyltransferase type 11; n=2;
Salinispora|Rep: Methyltransferase type 11 - Salinispora
tropica CNB-440
Length = 256
Score = 34.7 bits (76), Expect = 3.1
Identities = 22/60 (36%), Positives = 32/60 (53%)
Frame = +1
Query: 148 AARRAYSSNTDKNVAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGVTPANS 327
AA +S D + LG G G +A +L KG+ G D ++ AL AA++GVT N+
Sbjct: 41 AAMVPAASRPDALLVDLGCG--AGLLAPHLAGKGYRHVGVDLTRSALRQAAEHGVTVVNA 98
>UniRef50_A3Y0Y8 Cluster: Putative tartronate semialdehyde
reductase; n=1; Vibrio sp. MED222|Rep: Putative
tartronate semialdehyde reductase - Vibrio sp. MED222
Length = 83
Score = 34.7 bits (76), Expect = 3.1
Identities = 16/41 (39%), Positives = 23/41 (56%)
Frame = +1
Query: 187 VAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNG 309
+ F+GLG MGG M NL +G+ V D S++A+ G
Sbjct: 6 IGFIGLGLMGGNMVENLQTRGYHVNVMDLSEEAMARVTARG 46
>UniRef50_A3U721 Cluster: Putative uncharacterized protein; n=1;
Croceibacter atlanticus HTCC2559|Rep: Putative
uncharacterized protein - Croceibacter atlanticus
HTCC2559
Length = 273
Score = 34.7 bits (76), Expect = 3.1
Identities = 15/49 (30%), Positives = 29/49 (59%)
Frame = +1
Query: 178 DKNVAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGVTPAN 324
+K ++ LG G +G + L+ +G+TV+G +K+ L ++ G+ P N
Sbjct: 2 NKTISILGTGWLGLPLGKKLLDQGYTVKGSTTTKENLKLLSEVGIVPFN 50
>UniRef50_Q4WXG9 Cluster: 3-hydroxyisobutyrate dehydrogenase,
putative; n=1; Aspergillus fumigatus|Rep:
3-hydroxyisobutyrate dehydrogenase, putative -
Aspergillus fumigatus (Sartorya fumigata)
Length = 317
Score = 34.7 bits (76), Expect = 3.1
Identities = 21/61 (34%), Positives = 28/61 (45%), Gaps = 2/61 (3%)
Frame = +2
Query: 416 GVVAHAKKGSLLIDSSTIDXNVPQQIFPIALE--KGLGFTDAPVSGRVMGCSKRYLAFMA 589
GV+ + +L+D STID + + K F DAPVSG +G L FM
Sbjct: 102 GVLTTSVDDKILVDCSTIDTATSMDVGAAVCQNSKTAAFYDAPVSGGSLGAVAGTLTFMV 161
Query: 590 G 592
G
Sbjct: 162 G 162
Score = 33.9 bits (74), Expect = 5.4
Identities = 20/48 (41%), Positives = 28/48 (58%)
Frame = +3
Query: 714 GLTGMATAECMNMGIKMGLXPKGLVGTS*KTHRAPSLVDRRXYCPXPG 857
GL +ATAE MN+GIK G+ P L+ T A S ++ + + P PG
Sbjct: 195 GLIAIATAEAMNIGIKSGMKP-SLLARVFATSTAQSTINDK-WNPVPG 240
>UniRef50_A7DSF1 Cluster: 2-hydroxy-3-oxopropionate reductase; n=1;
Candidatus Nitrosopumilus maritimus SCM1|Rep:
2-hydroxy-3-oxopropionate reductase - Candidatus
Nitrosopumilus maritimus SCM1
Length = 292
Score = 34.7 bits (76), Expect = 3.1
Identities = 16/49 (32%), Positives = 27/49 (55%)
Frame = +1
Query: 181 KNVAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGVTPANS 327
K + +GLG +G + +L++ GF V ++ SKD A + G T +S
Sbjct: 2 KKIGIVGLGMLGNAVGLHLLESGFEVTVFNRSKDKTIQAKEKGATVVDS 50
Score = 34.7 bits (76), Expect = 3.1
Identities = 21/68 (30%), Positives = 32/68 (47%)
Frame = +2
Query: 410 KDGVVAHAKKGSLLIDSSTIDXNVPQQIFPIALEKGLGFTDAPVSGRVMGCSKRYLAFMA 589
++G++ K ++ D STID + + I LE G+ D PV G L MA
Sbjct: 78 REGIIKSENKKLIVADMSTIDPSESKNISDKFLEFGIHKLDIPVMGGPNVAITGDLVMMA 137
Query: 590 GXRKKNFE 613
K++FE
Sbjct: 138 SGNKESFE 145
>UniRef50_UPI0000E221EA Cluster: PREDICTED: similar to NMDAR1
subunit isoform 3b; n=1; Pan troglodytes|Rep: PREDICTED:
similar to NMDAR1 subunit isoform 3b - Pan troglodytes
Length = 886
Score = 34.3 bits (75), Expect = 4.1
Identities = 16/28 (57%), Positives = 19/28 (67%), Gaps = 1/28 (3%)
Frame = +3
Query: 177 RQECGFPRPRKHG-RIHGCELG*KGFHS 257
+QECG RPR+ G RIHG E G + HS
Sbjct: 489 KQECGSKRPRRSGARIHGQEKGARDLHS 516
>UniRef50_UPI000050FDFD Cluster: COG0569: K+ transport systems,
NAD-binding component; n=1; Brevibacterium linens
BL2|Rep: COG0569: K+ transport systems, NAD-binding
component - Brevibacterium linens BL2
Length = 233
Score = 34.3 bits (75), Expect = 4.1
Identities = 17/39 (43%), Positives = 24/39 (61%)
Frame = +1
Query: 187 VAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAK 303
VA +GLG GG +A LVK G V G D S++ ++ A+
Sbjct: 16 VAVIGLGRFGGSLARELVKHGVEVIGIDISEEVVSDYAE 54
>UniRef50_Q7WCB1 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=4;
Bordetella|Rep: 3-hydroxybutyryl-CoA dehydrogenase -
Bordetella parapertussis
Length = 354
Score = 34.3 bits (75), Expect = 4.1
Identities = 19/44 (43%), Positives = 24/44 (54%)
Frame = +1
Query: 172 NTDKNVAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAK 303
N +N+A +G G MG +AA KGF V DP AL AA+
Sbjct: 47 NPIQNLAVVGAGAMGSGIAALFASKGFDVVLIDPMAGALTRAAQ 90
>UniRef50_A4ECY9 Cluster: Putative uncharacterized protein; n=1;
Collinsella aerofaciens ATCC 25986|Rep: Putative
uncharacterized protein - Collinsella aerofaciens ATCC
25986
Length = 359
Score = 34.3 bits (75), Expect = 4.1
Identities = 23/87 (26%), Positives = 36/87 (41%)
Frame = +2
Query: 413 DGVVAHAKKGSLLIDSSTIDXNVPQQIFPIALEKGLGFTDAPVSGRVMGCSKRYLAFMAG 592
DG++ K G++LID +T + + I A G D PV+G G L + G
Sbjct: 82 DGLLTCTKPGAVLIDLTTSSPELARDIAEAAQVSGRMAFDCPVTGGESGAIAGTLTAIVG 141
Query: 593 XRKKNFERSLPLLQVMGANSXTADRSG 673
+ + +L AN D +G
Sbjct: 142 ATENDIAPVRDVLSTFAANICCFDGAG 168
>UniRef50_A3WMG5 Cluster: Probable 3-hydroxyisobutyrate
dehydrogenase; n=1; Idiomarina baltica OS145|Rep:
Probable 3-hydroxyisobutyrate dehydrogenase - Idiomarina
baltica OS145
Length = 284
Score = 34.3 bits (75), Expect = 4.1
Identities = 20/78 (25%), Positives = 36/78 (46%)
Frame = +2
Query: 443 SLLIDSSTIDXNVPQQIFPIALEKGLGFTDAPVSGRVMGCSKRYLAFMAGXRKKNFERSL 622
++ I+SST+ + +++ A ++G +APVSG L ++ G R+
Sbjct: 90 AIAIESSTLSVDWVKELAQQAQQRGKQLIEAPVSGSRPQAQNAELVYLVGGDAHLVNRAE 149
Query: 623 PLLQVMGANSXTADRSGS 676
P+L +MG GS
Sbjct: 150 PVLSLMGKKVNHTGEMGS 167
>UniRef50_A1SM51 Cluster: D-3-phosphoglycerate dehydrogenase; n=15;
Actinobacteria (class)|Rep: D-3-phosphoglycerate
dehydrogenase - Nocardioides sp. (strain BAA-499 /
JS614)
Length = 536
Score = 34.3 bits (75), Expect = 4.1
Identities = 29/93 (31%), Positives = 41/93 (44%)
Frame = +1
Query: 34 LKILSLLCARAHGRTLN*EKTNSKWPRAQY*STQCLYTAARRAYSSNTDKNVAFLGLGNM 213
L + +L A H + N +W RA+Y T+ LY +K V +GLG +
Sbjct: 113 LAVALMLAAARHISPAHAALKNGEWKRARYTGTE-LY-----------EKTVGIVGLGRI 160
Query: 214 GGFMAANLVKKGFTVRGYDPSKDALNAAAKNGV 312
G +A L G + YDP A AA+ GV
Sbjct: 161 GVLVAQRLSAFGMKIVAYDPYVQA-GRAAQMGV 192
>UniRef50_A0GI22 Cluster: 6-phosphogluconate dehydrogenase,
NAD-binding; n=1; Burkholderia phytofirmans PsJN|Rep:
6-phosphogluconate dehydrogenase, NAD-binding -
Burkholderia phytofirmans PsJN
Length = 355
Score = 34.3 bits (75), Expect = 4.1
Identities = 18/38 (47%), Positives = 22/38 (57%)
Frame = +2
Query: 518 LGFTDAPVSGRVMGCSKRYLAFMAGXRKKNFERSLPLL 631
+G+ DAPVSG V G + LA MAG + E PLL
Sbjct: 175 IGWIDAPVSGGVAGATAGTLAVMAGGAAADVEAVKPLL 212
>UniRef50_A0AWL7 Cluster: 6-phosphogluconate dehydrogenase,
NAD-binding precursor; n=1; Arthrobacter sp. FB24|Rep:
6-phosphogluconate dehydrogenase, NAD-binding precursor
- Arthrobacter sp. (strain FB24)
Length = 297
Score = 34.3 bits (75), Expect = 4.1
Identities = 18/46 (39%), Positives = 27/46 (58%), Gaps = 2/46 (4%)
Frame = +2
Query: 416 GVVAHAKKGSLLIDSSTIDXNVPQQIFP--IALEKGLGFTDAPVSG 547
GV+A + G+L++D +T D + Q + AL G + DAPVSG
Sbjct: 83 GVLAGLRAGALIVDMTTGDPELAQDVAQRVAALGNGARYVDAPVSG 128
>UniRef50_Q7NR40 Cluster: Probable 3-hydroxyisobutyrate
dehydrogenase; n=1; Chromobacterium violaceum|Rep:
Probable 3-hydroxyisobutyrate dehydrogenase -
Chromobacterium violaceum
Length = 296
Score = 33.9 bits (74), Expect = 5.4
Identities = 21/80 (26%), Positives = 35/80 (43%)
Frame = +2
Query: 404 WGKDGVVAHAKKGSLLIDSSTIDXNVPQQIFPIALEKGLGFTDAPVSGRVMGCSKRYLAF 583
+G +G+ + G L+D T + A G +AP++G V S L F
Sbjct: 82 FGDNGIASAPAAGRRLVDLGTHQPTQLAALGAEAAAAGWPLVEAPMTGSVHDASHGTLHF 141
Query: 584 MAGXRKKNFERSLPLLQVMG 643
+ G + + E + PLL +G
Sbjct: 142 LVGGAEADVEWASPLLWALG 161
>UniRef50_Q5GUM4 Cluster: Dehydrogenase; n=5;
Gammaproteobacteria|Rep: Dehydrogenase - Xanthomonas
oryzae pv. oryzae
Length = 335
Score = 33.9 bits (74), Expect = 5.4
Identities = 21/85 (24%), Positives = 37/85 (43%)
Frame = +2
Query: 416 GVVAHAKKGSLLIDSSTIDXNVPQQIFPIALEKGLGFTDAPVSGRVMGCSKRYLAFMAGX 595
GV+ GS+ ++ +TI + + + E+G+ + APV GRV L +AG
Sbjct: 120 GVLDALPAGSVHVNMATISVALAHALTALHAERGVAYVAAPVLGRVDVAEAGKLNILAGG 179
Query: 596 RKKNFERSLPLLQVMGANSXTADRS 670
R P+ +G + R+
Sbjct: 180 DDVAVARVQPMFDALGQKTWHIGRA 204
>UniRef50_Q0SAG5 Cluster: Phosphogluconate dehydrogenase; n=23;
Actinobacteria (class)|Rep: Phosphogluconate
dehydrogenase - Rhodococcus sp. (strain RHA1)
Length = 303
Score = 33.9 bits (74), Expect = 5.4
Identities = 21/75 (28%), Positives = 31/75 (41%)
Frame = +2
Query: 440 GSLLIDSSTIDXNVPQQIFPIALEKGLGFTDAPVSGRVMGCSKRYLAFMAGXRKKNFERS 619
G L+ID + + +G+G+ D VSG V G Y M G + ER+
Sbjct: 78 GDLVIDGGNSRYTDDKVHGELLGSRGIGYLDCGVSGGVWGLEDGY-GMMVGGSDADVERA 136
Query: 620 LPLLQVMGANSXTAD 664
LP+ + AD
Sbjct: 137 LPIFDALRPEGERAD 151
>UniRef50_Q3DWX0 Cluster: 6-phosphogluconate dehydrogenase,
NAD-binding; n=1; Chloroflexus aurantiacus J-10-fl|Rep:
6-phosphogluconate dehydrogenase, NAD-binding -
Chloroflexus aurantiacus J-10-fl
Length = 85
Score = 33.9 bits (74), Expect = 5.4
Identities = 18/47 (38%), Positives = 27/47 (57%)
Frame = +1
Query: 187 VAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGVTPANS 327
V F+GLG MG MA NL + GF+V ++ S+ ++ G+ A S
Sbjct: 15 VGFVGLGIMGKPMAHNLHRAGFSVMVWNRSRQPMDELPAEGLHSAES 61
>UniRef50_Q21ZT0 Cluster: 6-phosphogluconate dehydrogenase,
NAD-binding; n=1; Rhodoferax ferrireducens T118|Rep:
6-phosphogluconate dehydrogenase, NAD-binding -
Rhodoferax ferrireducens (strain DSM 15236 / ATCC
BAA-621 / T118)
Length = 315
Score = 33.9 bits (74), Expect = 5.4
Identities = 19/93 (20%), Positives = 37/93 (39%)
Frame = +2
Query: 398 CTWGKDGVVAHAKKGSLLIDSSTIDXNVPQQIFPIALEKGLGFTDAPVSGRVMGCSKRYL 577
C +G DG++ + G +++D++T D ++ +G + DAP++ +
Sbjct: 78 CVYGADGLLEGLRAGGVVVDATTADPVSTLKVAAAVQARGGRYVDAPMTRTSQHAEDGCV 137
Query: 578 AFMAGXRKKNFERSLPLLQVMGANSXTADRSGS 676
M G PL++ N GS
Sbjct: 138 NAMLGGDAVTIAEVRPLIEAYAENIFIGGEVGS 170
>UniRef50_Q033P2 Cluster: 3-hydroxyisobutyrate dehydrogenase related
beta-hydroxyacid dehydrogenase; n=1; Lactobacillus casei
ATCC 334|Rep: 3-hydroxyisobutyrate dehydrogenase related
beta-hydroxyacid dehydrogenase - Lactobacillus casei
(strain ATCC 334)
Length = 285
Score = 33.9 bits (74), Expect = 5.4
Identities = 16/48 (33%), Positives = 26/48 (54%)
Frame = +1
Query: 187 VAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGVTPANSI 330
+ F+G+G+MG M +L K G+ V +D + A A + V A S+
Sbjct: 3 ITFIGVGDMGSHMVPHLAKAGYDVTVWDKVPAKMAAVAGDHVRTATSL 50
>UniRef50_A6G079 Cluster: Leucine dehydrogenase; n=1; Plesiocystis
pacifica SIR-1|Rep: Leucine dehydrogenase - Plesiocystis
pacifica SIR-1
Length = 342
Score = 33.9 bits (74), Expect = 5.4
Identities = 18/38 (47%), Positives = 23/38 (60%)
Frame = +1
Query: 199 GLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGV 312
GLG++GG +AA LV+ G V G+DP A A GV
Sbjct: 172 GLGSVGGGLAAALVEAGGEVAGWDPDAAARAQAQALGV 209
>UniRef50_A4SGI3 Cluster: NAD-dependent epimerase/dehydratase; n=7;
Chlorobiaceae|Rep: NAD-dependent epimerase/dehydratase -
Prosthecochloris vibrioformis DSM 265
Length = 275
Score = 33.9 bits (74), Expect = 5.4
Identities = 16/47 (34%), Positives = 27/47 (57%)
Frame = +1
Query: 178 DKNVAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGVTP 318
++ V+ LG G +G +A L+KKGF V+G +++ L G+ P
Sbjct: 3 NQTVSILGCGWLGLPLAKALIKKGFIVKGSTTAEEHLEQLRTEGIEP 49
>UniRef50_A0Y665 Cluster: 6-phosphogluconate dehydrogenase; n=3;
Alteromonadales|Rep: 6-phosphogluconate dehydrogenase -
Alteromonadales bacterium TW-7
Length = 457
Score = 33.9 bits (74), Expect = 5.4
Identities = 16/33 (48%), Positives = 21/33 (63%)
Frame = +1
Query: 187 VAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDA 285
VA +GLG MG +A NL+ KG T+ YD + A
Sbjct: 3 VALVGLGVMGKNLALNLIDKGITLVAYDKNPHA 35
>UniRef50_Q8U2W2 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=17;
Pyrococcus|Rep: 3-hydroxyisobutyrate dehydrogenase -
Pyrococcus furiosus
Length = 278
Score = 33.9 bits (74), Expect = 5.4
Identities = 17/69 (24%), Positives = 32/69 (46%)
Frame = +2
Query: 437 KGSLLIDSSTIDXNVPQQIFPIALEKGLGFTDAPVSGRVMGCSKRYLAFMAGXRKKNFER 616
+G +++D++T + I G + ++PV G V+ L + ++ FER
Sbjct: 77 RGKIIVDTTTNHHEKVLEFHEIYRNVGAFYLESPVIGSVIPARNGQLTILVSGEREAFER 136
Query: 617 SLPLLQVMG 643
P LQ +G
Sbjct: 137 VRPYLQKLG 145
>UniRef50_A3H6C3 Cluster: 6-phosphogluconate dehydrogenase,
NAD-binding; n=1; Caldivirga maquilingensis IC-167|Rep:
6-phosphogluconate dehydrogenase, NAD-binding -
Caldivirga maquilingensis IC-167
Length = 284
Score = 33.9 bits (74), Expect = 5.4
Identities = 16/48 (33%), Positives = 25/48 (52%)
Frame = +1
Query: 187 VAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGVTPANSI 330
+ +GLG MG +A NL +KG V G+D +A + + V N +
Sbjct: 3 ICVIGLGRMGRGIAVNLSRKGHEVLGFDIDPNAAGRLSGSNVVVVNDM 50
>UniRef50_Q8EW87 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=1;
Mycoplasma penetrans|Rep: 3-hydroxyisobutyrate
dehydrogenase - Mycoplasma penetrans
Length = 288
Score = 33.5 bits (73), Expect = 7.1
Identities = 20/76 (26%), Positives = 37/76 (48%)
Frame = +2
Query: 416 GVVAHAKKGSLLIDSSTIDXNVPQQIFPIALEKGLGFTDAPVSGRVMGCSKRYLAFMAGX 595
G+ + + ID +T N Q+ + KG+ DAPV+G +G L+ M G
Sbjct: 80 GIFNYVSSEQICIDFTTSSPNFAVQLANNS--KGIKVLDAPVTGGDIGALNGTLSIMVGG 137
Query: 596 RKKNFERSLPLLQVMG 643
+ F++ +L+++G
Sbjct: 138 DFETFKKVESILKILG 153
>UniRef50_Q6N3Q8 Cluster: 6-phosphogluconate dehydrogenase; n=57;
Bacteria|Rep: 6-phosphogluconate dehydrogenase -
Rhodopseudomonas palustris
Length = 346
Score = 33.5 bits (73), Expect = 7.1
Identities = 15/48 (31%), Positives = 22/48 (45%)
Frame = +1
Query: 187 VAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGVTPANSI 330
+ +GLG MGG + L+K G YD A+ + G T A +
Sbjct: 3 IGMIGLGRMGGNIVRRLMKDGHHAVVYDRDPQAIETLTREGATGAGGL 50
>UniRef50_Q5LNV6 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=2;
Rhodobacteraceae|Rep: 3-hydroxyisobutyrate dehydrogenase
- Silicibacter pomeroyi
Length = 269
Score = 33.5 bits (73), Expect = 7.1
Identities = 20/79 (25%), Positives = 36/79 (45%)
Frame = +2
Query: 413 DGVVAHAKKGSLLIDSSTIDXNVPQQIFPIALEKGLGFTDAPVSGRVMGCSKRYLAFMAG 592
D + HAK +I ST+ + + + + DAP+SG + + L+FM G
Sbjct: 74 DQKLIHAKHLDCVIICSTLSPRYVRDL-RARVPDHIALIDAPMSGAQIAAQEARLSFMLG 132
Query: 593 XRKKNFERSLPLLQVMGAN 649
+ + + PL MG++
Sbjct: 133 GEPADLDAAQPLFAAMGSH 151
>UniRef50_Q6RXW5 Cluster: Succinic semialdehyde dehydrogenase; n=2;
Rhodococcus|Rep: Succinic semialdehyde dehydrogenase -
Rhodococcus sp. TK6
Length = 262
Score = 33.5 bits (73), Expect = 7.1
Identities = 16/44 (36%), Positives = 27/44 (61%)
Frame = +1
Query: 196 LGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGVTPANS 327
+GLG +GG + A+L + G V GYD +++ L ++ +PA S
Sbjct: 5 IGLGPIGGKIGAHLAELGRKVYGYDFNQERLREWSEETASPAGS 48
>UniRef50_Q0S6F7 Cluster: 3-demethylubiquinone-9
3-O-methyltransferase; n=1; Rhodococcus sp. RHA1|Rep:
3-demethylubiquinone-9 3-O-methyltransferase -
Rhodococcus sp. (strain RHA1)
Length = 279
Score = 33.5 bits (73), Expect = 7.1
Identities = 16/45 (35%), Positives = 25/45 (55%)
Frame = +1
Query: 196 LGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGVTPANSI 330
L +G+ GGF+A + GF V G DPS +++ A ++ A I
Sbjct: 58 LDVGSGGGFLAEEFTRIGFRVTGIDPSPVSVDTARRHAAGSALDI 102
>UniRef50_A5P600 Cluster: 6-phosphogluconate dehydrogenase,
NAD-binding; n=1; Methylobacterium sp. 4-46|Rep:
6-phosphogluconate dehydrogenase, NAD-binding -
Methylobacterium sp. 4-46
Length = 290
Score = 33.5 bits (73), Expect = 7.1
Identities = 19/75 (25%), Positives = 32/75 (42%)
Frame = +2
Query: 407 GKDGVVAHAKKGSLLIDSSTIDXNVPQQIFPIALEKGLGFTDAPVSGRVMGCSKRYLAFM 586
G +G++A +L+++ST+ + A G+ + APVSG L
Sbjct: 72 GPEGLLARMAPDGVLVETSTVSPETSAALREAAEAGGILYLAAPVSGSTATAEAATLTLF 131
Query: 587 AGXRKKNFERSLPLL 631
+ ER+ PLL
Sbjct: 132 CSGPETALERARPLL 146
>UniRef50_A0Z3U5 Cluster: Putative uncharacterized protein; n=1;
marine gamma proteobacterium HTCC2080|Rep: Putative
uncharacterized protein - marine gamma proteobacterium
HTCC2080
Length = 150
Score = 33.5 bits (73), Expect = 7.1
Identities = 13/36 (36%), Positives = 22/36 (61%), Gaps = 1/36 (2%)
Frame = +2
Query: 137 VCTQPPDGRIVLTPTRMWLSSASETW-EDSWLRTWL 241
+ T DG + TP+R WL++ ++W E+ W+R L
Sbjct: 60 IVTHGSDGSLSTTPSREWLTAPMDSWREEGWVRAEL 95
Database: uniref50
Posted date: Oct 5, 2007 11:19 AM
Number of letters in database: 575,637,011
Number of sequences in database: 1,657,284
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 883,147,988
Number of Sequences: 1657284
Number of extensions: 17944513
Number of successful extensions: 44605
Number of sequences better than 10.0: 267
Number of HSP's better than 10.0 without gapping: 42442
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 44544
length of database: 575,637,011
effective HSP length: 100
effective length of database: 409,908,611
effective search space used: 77472727479
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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