Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= MFBP07_F_D23
(883 letters)
Database: uniref50
1,657,284 sequences; 575,637,011 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
UniRef50_P31937 Cluster: 3-hydroxyisobutyrate dehydrogenase, mit... 193 6e-48
UniRef50_UPI0000D56743 Cluster: PREDICTED: similar to 3-hydroxyi... 191 2e-47
UniRef50_Q9V8M5 Cluster: Probable 3-hydroxyisobutyrate dehydroge... 189 9e-47
UniRef50_Q399N0 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=7... 184 2e-45
UniRef50_Q54CX6 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=3... 182 8e-45
UniRef50_Q7NWA9 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=7... 169 1e-40
UniRef50_Q83D20 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=9... 156 6e-37
UniRef50_Q2UHA9 Cluster: Predicted dehydrogenase; n=16; Pezizomy... 155 1e-36
UniRef50_UPI00015B4162 Cluster: PREDICTED: similar to MGC108315 ... 154 3e-36
UniRef50_P28811 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=7... 153 6e-36
UniRef50_Q9A8J9 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=2... 153 8e-36
UniRef50_A7UBP6 Cluster: Putative 3-hydroxyisobutyrate dehydroge... 152 1e-35
UniRef50_Q22B54 Cluster: 3-hydroxyisobutyrate dehydrogenase fami... 151 3e-35
UniRef50_Q9SUC0 Cluster: Probable 3-hydroxyisobutyrate dehydroge... 147 3e-34
UniRef50_Q0K0E2 Cluster: 3-Hydroxyisobutyrate dehydrogenase; n=1... 146 7e-34
UniRef50_Q6C351 Cluster: Yarrowia lipolytica chromosome F of str... 141 2e-32
UniRef50_A0QSJ0 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=3... 139 7e-32
UniRef50_A0C2T7 Cluster: Chromosome undetermined scaffold_145, w... 139 1e-31
UniRef50_A7JGH8 Cluster: Predicted protein; n=1; Francisella tul... 134 2e-30
UniRef50_P63936 Cluster: Probable 3-hydroxyisobutyrate dehydroge... 132 1e-29
UniRef50_Q4PCH4 Cluster: Putative uncharacterized protein; n=1; ... 129 8e-29
UniRef50_Q0URA2 Cluster: Putative uncharacterized protein; n=1; ... 124 3e-27
UniRef50_A1QPH6 Cluster: 3-hydroxyisobutyrate dehydrogenase mmsB... 114 2e-24
UniRef50_Q0C8I2 Cluster: Predicted protein; n=3; Pezizomycotina|... 113 4e-24
UniRef50_A0GVR3 Cluster: 6-phosphogluconate dehydrogenase, NAD-b... 111 2e-23
UniRef50_A6NVP0 Cluster: Putative uncharacterized protein; n=1; ... 111 3e-23
UniRef50_Q1V2R0 Cluster: MmsB-like protein; n=2; Candidatus Pela... 110 5e-23
UniRef50_A3I4V2 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=1... 109 9e-23
UniRef50_Q4ZQL5 Cluster: 3-hydroxyisobutyrate dehydrogenase prec... 108 2e-22
UniRef50_Q0QLF5 Cluster: 2-hydroxymethyl glutarate dehydrogenase... 108 2e-22
UniRef50_Q67QX0 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=1... 105 1e-21
UniRef50_Q55702 Cluster: Uncharacterized oxidoreductase slr0229;... 103 5e-21
UniRef50_A1SIN3 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=1... 102 1e-20
UniRef50_A0JUJ6 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=2... 102 1e-20
UniRef50_A3H5R1 Cluster: 6-phosphogluconate dehydrogenase, NAD-b... 101 3e-20
UniRef50_Q9LNP0 Cluster: F1L3.35; n=8; Magnoliophyta|Rep: F1L3.3... 98 3e-19
UniRef50_Q8ES28 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=1... 97 5e-19
UniRef50_Q1GJB9 Cluster: 6-phosphogluconate dehydrogenase NAD-bi... 97 7e-19
UniRef50_Q01QM2 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=1... 97 7e-19
UniRef50_A3LTC4 Cluster: 3-hydroxyisobutyrate dehydrogenase-like... 96 9e-19
UniRef50_Q55W03 Cluster: Putative uncharacterized protein; n=2; ... 95 2e-18
UniRef50_Q1AVA4 Cluster: 2-hydroxy-3-oxopropionate reductase; n=... 94 4e-18
UniRef50_Q13LQ9 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=1... 94 4e-18
UniRef50_Q9K9L1 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=2... 94 5e-18
UniRef50_A2U9T6 Cluster: 6-phosphogluconate dehydrogenase, NAD-b... 93 6e-18
UniRef50_Q0UVR9 Cluster: Putative uncharacterized protein; n=1; ... 93 1e-17
UniRef50_Q606G9 Cluster: Oxidoreductase, Gfo/Idh/MocA family; n=... 92 2e-17
UniRef50_Q656T5 Cluster: Oxidoreductase-like; n=3; Oryza sativa|... 91 3e-17
UniRef50_Q8KL12 Cluster: Probable 6-phosphogluconate dehydrogena... 90 6e-17
UniRef50_P0ABQ3 Cluster: 2-hydroxy-3-oxopropionate reductase; n=... 90 6e-17
UniRef50_Q8U2W2 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=1... 90 8e-17
UniRef50_A0FZ96 Cluster: 6-phosphogluconate dehydrogenase, NAD-b... 89 1e-16
UniRef50_Q0S5S3 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=1... 89 2e-16
UniRef50_Q4WXG9 Cluster: 3-hydroxyisobutyrate dehydrogenase, put... 88 2e-16
UniRef50_A0JXR2 Cluster: 2-hydroxy-3-oxopropionate reductase; n=... 88 3e-16
UniRef50_A3RRS1 Cluster: 2-hydroxy-3-oxopropionate reductase; n=... 87 4e-16
UniRef50_Q9HLR4 Cluster: Putative uncharacterized protein Ta0161... 87 4e-16
UniRef50_Q2BFK1 Cluster: Oxidoreductase; n=1; Bacillus sp. NRRL ... 87 6e-16
UniRef50_Q13PY3 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=2... 87 6e-16
UniRef50_Q97XZ7 Cluster: Oxidoreductase; n=6; Thermoprotei|Rep: ... 87 6e-16
UniRef50_Q0LNZ7 Cluster: 3-hydroxyisobutyrate dehydrogenase prec... 87 7e-16
UniRef50_Q41DK0 Cluster: 6-phosphogluconate dehydrogenase, NAD-b... 86 1e-15
UniRef50_Q3DYV4 Cluster: NADP oxidoreductase, coenzyme F420-depe... 86 1e-15
UniRef50_A0N0V2 Cluster: BtdhL; n=1; Azoarcus anaerobius|Rep: Bt... 86 1e-15
UniRef50_Q89UN2 Cluster: Bll1384 protein; n=9; Bacteria|Rep: Bll... 86 1e-15
UniRef50_Q1QWU9 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=1... 85 2e-15
UniRef50_A5V0D4 Cluster: 6-phosphogluconate dehydrogenase, NAD-b... 85 2e-15
UniRef50_Q89HA0 Cluster: Oxidoreductase; n=1; Bradyrhizobium jap... 85 2e-15
UniRef50_Q18X68 Cluster: 6-phosphogluconate dehydrogenase, NAD-b... 85 2e-15
UniRef50_Q58PL4 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=1... 84 4e-15
UniRef50_Q01ZG6 Cluster: 2-hydroxy-3-oxopropionate reductase; n=... 84 4e-15
UniRef50_A0LDJ3 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=1... 84 5e-15
UniRef50_A0GI22 Cluster: 6-phosphogluconate dehydrogenase, NAD-b... 84 5e-15
UniRef50_Q97ZE5 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=4... 84 5e-15
UniRef50_O34948 Cluster: Uncharacterized oxidoreductase ykwC; n=... 84 5e-15
UniRef50_Q4KH51 Cluster: 3-hydroxyisobutyrate dehydrogenase fami... 83 7e-15
UniRef50_Q84VC8 Cluster: Gamma hydroxybutyrate dehydrogenase-lik... 83 7e-15
UniRef50_Q4FMJ3 Cluster: 6-phosphogluconate dehydrogenase; n=2; ... 83 9e-15
UniRef50_Q11FC5 Cluster: 6-phosphogluconate dehydrogenase, NAD-b... 83 9e-15
UniRef50_A0UF54 Cluster: 6-phosphogluconate dehydrogenase, NAD-b... 83 9e-15
UniRef50_Q4Q7T9 Cluster: 2-hydroxy-3-oxopropionate reductase, pu... 83 9e-15
UniRef50_Q7WG50 Cluster: Probable oxidoreductase; n=1; Bordetell... 83 1e-14
UniRef50_A6SW62 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=1... 83 1e-14
UniRef50_A5P0V0 Cluster: 6-phosphogluconate dehydrogenase, NAD-b... 83 1e-14
UniRef50_Q0QWD5 Cluster: Putative 3-hydroxyisobutyrate dehydroge... 83 1e-14
UniRef50_Q1N6I0 Cluster: Putative oxidoreductase protein; n=1; O... 81 4e-14
UniRef50_Q12CU4 Cluster: 2-hydroxy-3-oxopropionate reductase; n=... 81 4e-14
UniRef50_A1WM48 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=1... 81 4e-14
UniRef50_A1B741 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=3... 81 5e-14
UniRef50_A0G5F9 Cluster: 6-phosphogluconate dehydrogenase, NAD-b... 81 5e-14
UniRef50_UPI00003C03F8 Cluster: PREDICTED: similar to CG4747-PA;... 80 6e-14
UniRef50_A0LMG6 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=9... 80 6e-14
UniRef50_Q92D17 Cluster: Lin1004 protein; n=10; Bacilli|Rep: Lin... 80 8e-14
UniRef50_Q8PK98 Cluster: 3-hydroxyisobutirate dehydrogenase; n=3... 80 8e-14
UniRef50_A3K497 Cluster: Probable 6-phosphogluconate dehydrogena... 80 8e-14
UniRef50_Q5WBB8 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=1... 79 1e-13
UniRef50_Q94B07 Cluster: Gamma hydroxybutyrate dehydrogenase; n=... 79 1e-13
UniRef50_UPI0000E49FD0 Cluster: PREDICTED: similar to gamma hydr... 78 3e-13
UniRef50_Q2JEV5 Cluster: 6-phosphogluconate dehydrogenase, NAD-b... 78 3e-13
UniRef50_O66454 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=3... 78 3e-13
UniRef50_A5GPC0 Cluster: Hydroxyacid dehydrogenase/reductase fam... 78 3e-13
UniRef50_A1UP64 Cluster: 6-phosphogluconate dehydrogenase, NAD-b... 78 3e-13
UniRef50_Q3W9W7 Cluster: 6-phosphogluconate dehydrogenase, NAD b... 78 3e-13
UniRef50_Q183P5 Cluster: 2-hydroxy-3-oxopropionate reductase; n=... 78 3e-13
UniRef50_A3X9R7 Cluster: 3-hydroxyisobutyrate dehydrogenase fami... 77 5e-13
UniRef50_Q47AR2 Cluster: NADP oxidoreductase, coenzyme F420-depe... 77 6e-13
UniRef50_A3WMG5 Cluster: Probable 3-hydroxyisobutyrate dehydroge... 77 6e-13
UniRef50_Q019Z7 Cluster: Oxidoreductase-like; n=1; Ostreococcus ... 77 8e-13
UniRef50_Q0RCX7 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=1... 76 1e-12
UniRef50_A5FTT0 Cluster: 6-phosphogluconate dehydrogenase, NAD-b... 76 1e-12
UniRef50_Q830A7 Cluster: 2-hydroxy-3-oxopropionate reductase; n=... 76 1e-12
UniRef50_Q7VYY0 Cluster: Putative oxidoreductase; n=4; Bordetell... 76 1e-12
UniRef50_Q39FA8 Cluster: 2-hydroxy-3-oxopropionate reductase; n=... 76 1e-12
UniRef50_Q121N3 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=1... 76 1e-12
UniRef50_Q0SBQ9 Cluster: 2-hydroxy-3-oxopropionate reductase; n=... 76 1e-12
UniRef50_Q6UCZ9 Cluster: Predicted oxidoreductase; n=2; environm... 75 2e-12
UniRef50_Q930C6 Cluster: Probable; n=8; Alphaproteobacteria|Rep:... 75 2e-12
UniRef50_UPI00015B4B33 Cluster: PREDICTED: similar to 3-hydroxyi... 74 4e-12
UniRef50_Q89R44 Cluster: Oxidoreductase; n=23; Bacteria|Rep: Oxi... 74 4e-12
UniRef50_A6VYD9 Cluster: 2-hydroxy-3-oxopropionate reductase pre... 74 4e-12
UniRef50_A3EW86 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=1... 74 4e-12
UniRef50_Q0F1Y7 Cluster: 6-phosphogluconate dehydrogenase, NAD-b... 74 6e-12
UniRef50_A4SWE8 Cluster: 2-hydroxy-3-oxopropionate reductase pre... 74 6e-12
UniRef50_Q9JYH6 Cluster: 3-hydroxyacid dehydrogenase; n=5; Prote... 73 7e-12
UniRef50_A4IN46 Cluster: 3-hydroxyisobutyrate dehydrogenase-like... 73 7e-12
UniRef50_Q7WCG3 Cluster: Putative uncharacterized protein; n=2; ... 73 1e-11
UniRef50_A1R2J4 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=1... 73 1e-11
UniRef50_P77161 Cluster: 2-hydroxy-3-oxopropionate reductase; n=... 73 1e-11
UniRef50_Q1QWQ5 Cluster: 6-phosphogluconate dehydrogenase, NAD-b... 73 1e-11
UniRef50_Q03UI4 Cluster: 3-hydroxyisobutyrate dehydrogenase rela... 73 1e-11
UniRef50_A3SJ77 Cluster: Probable oxidoreductase; n=1; Roseovari... 72 2e-11
UniRef50_Q5L168 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=1... 72 2e-11
UniRef50_Q1IQE6 Cluster: 2-hydroxy-3-oxopropionate reductase pre... 71 3e-11
UniRef50_Q8EW87 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=1... 71 4e-11
UniRef50_A2SP40 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=1... 71 4e-11
UniRef50_Q73P00 Cluster: 3-hydroxyacid dehydrogenase family prot... 71 5e-11
UniRef50_Q9LM23 Cluster: Fructose-bisphosphate aldolase; n=2; Ar... 71 5e-11
UniRef50_Q8VYC5 Cluster: Fructose-bisphosphate aldolase; n=12; c... 71 5e-11
UniRef50_Q7WNK6 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=1... 70 7e-11
UniRef50_Q7NEW9 Cluster: Glr3759 protein; n=3; Bacteria|Rep: Glr... 70 7e-11
UniRef50_A0QZR7 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=1... 70 7e-11
UniRef50_A6SUL3 Cluster: 2-hydroxy-3-oxopropionate reductase; n=... 70 9e-11
UniRef50_Q7Q161 Cluster: ENSANGP00000013149; n=11; Culicidae|Rep... 69 1e-10
UniRef50_A2C1U6 Cluster: 3-hydroxyisobutyrate dehydrogenase and ... 69 2e-10
UniRef50_A0G5G5 Cluster: 6-phosphogluconate dehydrogenase, NAD-b... 69 2e-10
UniRef50_A7PEG7 Cluster: Chromosome chr11 scaffold_13, whole gen... 69 2e-10
UniRef50_A7IE35 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=2... 69 2e-10
UniRef50_Q9RX16 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=6... 68 3e-10
UniRef50_Q0BTJ3 Cluster: 2-hydroxy-3-oxopropionate reductase; n=... 68 3e-10
UniRef50_A6G049 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=1... 68 3e-10
UniRef50_O33730 Cluster: Uncharacterized oxidoreductase Sfri_150... 68 3e-10
UniRef50_A6LT11 Cluster: 6-phosphogluconate dehydrogenase, NAD-b... 68 4e-10
UniRef50_A5USN9 Cluster: 6-phosphogluconate dehydrogenase, NAD-b... 68 4e-10
UniRef50_Q0FFH2 Cluster: Putative 2-hydroxyacid dehydrogenase; n... 67 6e-10
UniRef50_A6GTB5 Cluster: 6-phosphogluconate dehydrogenase, NAD-b... 67 6e-10
UniRef50_A3WAC4 Cluster: Dehydrogenase; n=4; Bacteria|Rep: Dehyd... 66 8e-10
UniRef50_A1CAY2 Cluster: Oxidoreductase, acting on the CH-OH gro... 66 1e-09
UniRef50_Q9L7S0 Cluster: Uncharacterized oxidoreductase yihU; n=... 66 1e-09
UniRef50_UPI0000D55E08 Cluster: PREDICTED: similar to CG4747-PA;... 66 1e-09
UniRef50_A1ZWM5 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=1... 66 1e-09
UniRef50_A0K0Z6 Cluster: 6-phosphogluconate dehydrogenase, NAD-b... 66 1e-09
UniRef50_A5VBF0 Cluster: 2-hydroxy-3-oxopropionate reductase pre... 65 2e-09
UniRef50_A7I8V1 Cluster: 6-phosphogluconate dehydrogenase, NAD-b... 65 2e-09
UniRef50_Q39MY1 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=2... 65 3e-09
UniRef50_A6P2M7 Cluster: Putative uncharacterized protein; n=2; ... 64 3e-09
UniRef50_Q8TT25 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=2... 64 3e-09
UniRef50_Q1YHQ4 Cluster: Putative 2-hydroxy-3-oxopropionate redu... 64 5e-09
UniRef50_A6EH53 Cluster: Putative uncharacterized protein; n=1; ... 64 5e-09
UniRef50_Q4WV01 Cluster: Oxidoreductase, acting on the CH-OH gro... 63 8e-09
UniRef50_Q8F4I7 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=4... 63 1e-08
UniRef50_A0QUD5 Cluster: 3-hydroxyisobutyrate dehydrogenase fami... 63 1e-08
UniRef50_Q46TQ0 Cluster: UDP-glucose/GDP-mannose dehydrogenase:P... 62 1e-08
UniRef50_A0RU56 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=1... 62 2e-08
UniRef50_A5WG80 Cluster: 6-phosphogluconate dehydrogenase, NAD-b... 62 2e-08
UniRef50_A5VEA3 Cluster: 2-hydroxy-3-oxopropionate reductase; n=... 61 3e-08
UniRef50_Q6F842 Cluster: Putative 3-hydroxyisobutyrate dehydroge... 60 6e-08
UniRef50_A1WJN2 Cluster: 6-phosphogluconate dehydrogenase, NAD-b... 60 6e-08
UniRef50_A7DSF1 Cluster: 2-hydroxy-3-oxopropionate reductase; n=... 60 7e-08
UniRef50_UPI0000EBE4FC Cluster: PREDICTED: hypothetical protein;... 60 1e-07
UniRef50_A4S5A4 Cluster: Predicted protein; n=2; Ostreococcus|Re... 60 1e-07
UniRef50_Q49A26 Cluster: Cytokine-like nuclear factor n-pac; n=4... 60 1e-07
UniRef50_A1GFG2 Cluster: 6-phosphogluconate dehydrogenase, NAD-b... 59 1e-07
UniRef50_Q0KC92 Cluster: 3-Hydroxyisobutyrate dehydrogenase; n=1... 59 2e-07
UniRef50_A1SQ87 Cluster: 6-phosphogluconate dehydrogenase, NAD-b... 59 2e-07
UniRef50_A0R1N4 Cluster: 6-phosphogluconate dehydrogenase, NAD-b... 59 2e-07
UniRef50_A7DWL2 Cluster: Putative dehydrogenase; n=1; Streptomyc... 58 2e-07
UniRef50_A6F020 Cluster: Putative uncharacterized protein; n=1; ... 58 2e-07
UniRef50_Q2CHC8 Cluster: Oxidoreductase; n=1; Oceanicola granulo... 58 4e-07
UniRef50_Q3W3N3 Cluster: Putative uncharacterized protein; n=1; ... 57 5e-07
UniRef50_Q5LNV6 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=2... 57 7e-07
UniRef50_A1UJF2 Cluster: 6-phosphogluconate dehydrogenase, NAD-b... 57 7e-07
UniRef50_A3VLN6 Cluster: Oxidoreductase; n=1; Rhodobacterales ba... 56 9e-07
UniRef50_Q1EPJ1 Cluster: 6-phosphogluconate dehydrogenase NAD-bi... 56 1e-06
UniRef50_Q9I1R8 Cluster: Probable dehydrogenase; n=7; Pseudomona... 56 2e-06
UniRef50_Q7NR40 Cluster: Probable 3-hydroxyisobutyrate dehydroge... 56 2e-06
UniRef50_A0NRG5 Cluster: 6-phosphogluconate dehydrogenase, NAD-b... 56 2e-06
UniRef50_A0K107 Cluster: 2-hydroxy-3-oxopropionate reductase; n=... 56 2e-06
UniRef50_Q5FQ06 Cluster: Putative oxidoreductase; n=1; Gluconoba... 55 2e-06
UniRef50_Q01PV6 Cluster: 6-phosphogluconate dehydrogenase, NAD-b... 55 2e-06
UniRef50_A0GPK7 Cluster: 6-phosphogluconate dehydrogenase, NAD-b... 55 2e-06
UniRef50_Q84H84 Cluster: Putative oxidoreductase; n=1; Arthrobac... 55 3e-06
UniRef50_Q20XN2 Cluster: 6-phosphogluconate dehydrogenase, NAD-b... 55 3e-06
UniRef50_A3Y8R5 Cluster: Putative dehydrogenase; n=1; Marinomona... 55 3e-06
UniRef50_A1WS34 Cluster: Putative uncharacterized protein; n=1; ... 54 4e-06
UniRef50_A3ET09 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=3... 54 5e-06
UniRef50_A1WEB7 Cluster: 6-phosphogluconate dehydrogenase, NAD-b... 54 5e-06
UniRef50_UPI0001597301 Cluster: YfjR; n=1; Bacillus amyloliquefa... 54 6e-06
UniRef50_A0LTQ8 Cluster: 6-phosphogluconate dehydrogenase, NAD-b... 53 8e-06
UniRef50_Q4Q9Z1 Cluster: Dehydrogenase-like protein; n=6; Trypan... 53 8e-06
UniRef50_A0YMN9 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=3... 53 1e-05
UniRef50_A6R0U9 Cluster: Predicted protein; n=1; Ajellomyces cap... 53 1e-05
UniRef50_Q3WJ00 Cluster: 6-phosphogluconate dehydrogenase, NAD b... 52 1e-05
UniRef50_Q98I20 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=2... 52 2e-05
UniRef50_Q74D68 Cluster: 3-hydroxyisobutyrate dehydrogenase fami... 52 2e-05
UniRef50_A6RMW8 Cluster: Putative uncharacterized protein; n=2; ... 52 2e-05
UniRef50_A3JU55 Cluster: Predicted dehydrogenase, with NAD(P)-bi... 52 3e-05
UniRef50_A7RG59 Cluster: Predicted protein; n=1; Nematostella ve... 52 3e-05
UniRef50_Q5LQR0 Cluster: 6-phosphogluconate dehydrogenase domain... 51 3e-05
UniRef50_Q8UBW3 Cluster: Oxidoredutase; n=1; Agrobacterium tumef... 51 4e-05
UniRef50_A0JRK4 Cluster: 6-phosphogluconate dehydrogenase, NAD-b... 51 4e-05
UniRef50_A3H6C3 Cluster: 6-phosphogluconate dehydrogenase, NAD-b... 51 4e-05
UniRef50_Q6RXW5 Cluster: Succinic semialdehyde dehydrogenase; n=... 50 6e-05
UniRef50_A0VSV4 Cluster: 6-phosphogluconate dehydrogenase, NAD-b... 50 6e-05
UniRef50_A0R1N5 Cluster: 6-phosphogluconate dehydrogenase, NAD-b... 50 6e-05
UniRef50_O34969 Cluster: Uncharacterized oxidoreductase yfjR; n=... 50 6e-05
UniRef50_Q21AH6 Cluster: 6-phosphogluconate dehydrogenase, NAD-b... 50 8e-05
UniRef50_A4FKN9 Cluster: 2-hydroxy-3-oxopropionate reductase; n=... 50 1e-04
UniRef50_A4ECY9 Cluster: Putative uncharacterized protein; n=1; ... 49 1e-04
UniRef50_Q1V2K7 Cluster: NADP oxidoreductase, coenzyme F420-depe... 48 2e-04
UniRef50_Q1GF31 Cluster: 6-phosphogluconate dehydrogenase NAD-bi... 48 2e-04
UniRef50_Q12H32 Cluster: 6-phosphogluconate dehydrogenase, NAD-b... 48 2e-04
UniRef50_Q8T079 Cluster: LD22344p; n=2; Sophophora|Rep: LD22344p... 48 2e-04
UniRef50_P71825 Cluster: Uncharacterized oxidoreductase Rv0770/M... 48 2e-04
UniRef50_Q8YRT5 Cluster: 3-hydroxyacid dehydrogenase; n=5; Cyano... 48 4e-04
UniRef50_Q39KK8 Cluster: 6-phosphogluconate dehydrogenase, NAD-b... 48 4e-04
UniRef50_Q3W9L4 Cluster: Putative uncharacterized protein; n=1; ... 48 4e-04
UniRef50_A7H7Z5 Cluster: 6-phosphogluconate dehydrogenase NAD-bi... 48 4e-04
UniRef50_A1UJF3 Cluster: 6-phosphogluconate dehydrogenase, NAD-b... 48 4e-04
UniRef50_A3PRM1 Cluster: 6-phosphogluconate dehydrogenase, NAD-b... 47 7e-04
UniRef50_Q89M84 Cluster: Blr4309 protein; n=6; Bradyrhizobiaceae... 46 0.001
UniRef50_Q5MZU3 Cluster: 3-hydroxyacid dehydrogenase; n=3; Cyano... 46 0.002
UniRef50_Q0RIL5 Cluster: Putative uncharacterized protein; n=1; ... 45 0.002
UniRef50_Q1B326 Cluster: 6-phosphogluconate dehydrogenase, NAD-b... 44 0.004
UniRef50_A5GJY3 Cluster: 3-hydroxyisobutyrate dehydrogenase rela... 44 0.004
UniRef50_UPI0000F1E276 Cluster: PREDICTED: similar to G protein-... 44 0.007
UniRef50_A3Q3U7 Cluster: 6-phosphogluconate dehydrogenase, NAD-b... 43 0.009
UniRef50_A0FZ97 Cluster: 6-phosphogluconate dehydrogenase, NAD-b... 43 0.009
UniRef50_A3ES45 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=1... 42 0.016
UniRef50_Q9K9H3 Cluster: 6-phosphogluconate dehydrogenase; n=7; ... 42 0.021
UniRef50_Q2JEN4 Cluster: 6-phosphogluconate dehydrogenase, NAD-b... 42 0.021
UniRef50_Q629W3 Cluster: 2-hydroxy-3-oxopropionate reductase; n=... 42 0.027
UniRef50_A1RWA6 Cluster: 6-phosphogluconate dehydrogenase, NAD-b... 42 0.027
UniRef50_Q5GUM4 Cluster: Dehydrogenase; n=5; Gammaproteobacteria... 41 0.048
UniRef50_Q221W9 Cluster: 2-hydroxy-3-oxopropionate reductase; n=... 40 0.084
UniRef50_A3PSD9 Cluster: 6-phosphogluconate dehydrogenase, decar... 39 0.15
UniRef50_Q0SAG5 Cluster: Phosphogluconate dehydrogenase; n=23; A... 38 0.34
UniRef50_A4JSC3 Cluster: 6-phosphogluconate dehydrogenase, NAD-b... 38 0.34
UniRef50_A4BV63 Cluster: 3-hydroxyacid dehydrogenase; n=1; Nitro... 38 0.34
UniRef50_A1C8I6 Cluster: NAD binding NADP oxidoreductase coenzym... 38 0.34
UniRef50_Q392H4 Cluster: 6-phosphogluconate dehydrogenase, NAD-b... 38 0.45
UniRef50_Q55JR1 Cluster: Putative uncharacterized protein; n=2; ... 38 0.45
UniRef50_Q1NHG5 Cluster: Putative uncharacterized protein; n=1; ... 37 0.59
UniRef50_Q1GM24 Cluster: 6-phosphogluconate dehydrogenase NAD-bi... 37 0.59
UniRef50_Q4RNR1 Cluster: Chromosome 2 SCAF15010, whole genome sh... 37 0.78
UniRef50_Q9RNC5 Cluster: Putative 3-hydroxyacid dehydrogenase; n... 36 1.0
UniRef50_A3H9B3 Cluster: 6-phosphogluconate dehydrogenase, NAD-b... 36 1.0
UniRef50_Q98K09 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=7... 35 2.4
UniRef50_Q21ZT0 Cluster: 6-phosphogluconate dehydrogenase, NAD-b... 35 3.2
UniRef50_Q1NHF5 Cluster: Putative oxidoreductase; n=1; Sphingomo... 35 3.2
UniRef50_Q1INE9 Cluster: 6-phosphogluconate dehydrogenase, NAD-b... 34 4.2
UniRef50_A5BSQ5 Cluster: Putative uncharacterized protein; n=1; ... 34 4.2
UniRef50_Q89GM2 Cluster: Bll6323 protein; n=6; Proteobacteria|Re... 34 5.5
UniRef50_O66788 Cluster: 6-phosphogluconate dehydrogenase; n=2; ... 34 5.5
UniRef50_A0AWL7 Cluster: 6-phosphogluconate dehydrogenase, NAD-b... 34 5.5
UniRef50_UPI0000EBD7FD Cluster: PREDICTED: hypothetical protein;... 33 7.3
>UniRef50_P31937 Cluster: 3-hydroxyisobutyrate dehydrogenase,
mitochondrial precursor; n=38; Eumetazoa|Rep:
3-hydroxyisobutyrate dehydrogenase, mitochondrial
precursor - Homo sapiens (Human)
Length = 336
Score = 193 bits (470), Expect = 6e-48
Identities = 90/185 (48%), Positives = 125/185 (67%)
Frame = -3
Query: 695 RKGLGFTXAPVXGGVMGAQNVTXAFMAGGXKEDFERSLXLLKVMGXKQFHCGQIGSGQVA 516
+ G F APV GGV A++ FM GG +++F + LL MG +CG +G+GQ A
Sbjct: 149 KMGAVFMDAPVSGGVGAARSGNLTFMVGGVEDEFAAAQELLGCMGSNVVYCGAVGTGQAA 208
Query: 515 KLTNNMLMGITGMATAECMNMGIKMGLEPKVLLDVLNNSSARSWSTEVYCPVPGLVPTAP 336
K+ NNML+ I+ + TAE MN+GI++GL+PK+L +LN SS R WS++ Y PVPG++ P
Sbjct: 209 KICNNMLLAISMIGTAEAMNLGIRLGLDPKLLAKILNMSSGRCWSSDTYNPVPGVMDGVP 268
Query: 335 SSRNYDGGFKNELMVKDLELASGMALGIRSPIPLGAVAXQLYRIVQSRGYGQKDFSFVFQ 156
S+ NY GGF LM KDL LA A +SPI LG++A Q+YR++ ++GY +KDFS VFQ
Sbjct: 269 SANNYQGGFGTTLMAKDLGLAQDSATSTKSPILLGSLAHQIYRMMCAKGYSKKDFSSVFQ 328
Query: 155 LLKEE 141
L+EE
Sbjct: 329 FLREE 333
>UniRef50_UPI0000D56743 Cluster: PREDICTED: similar to
3-hydroxyisobutyrate dehydrogenase; n=1; Tribolium
castaneum|Rep: PREDICTED: similar to
3-hydroxyisobutyrate dehydrogenase - Tribolium castaneum
Length = 315
Score = 191 bits (466), Expect = 2e-47
Identities = 90/181 (49%), Positives = 117/181 (64%)
Frame = -3
Query: 689 GLGFTXAPVXGGVMGAQNVTXAFMAGGXKEDFERSLXLLKVMGXKQFHCGQIGSGQVAKL 510
G F APV GGV GA+ T FM GG K+ + +L MG HCG G+GQ+AKL
Sbjct: 133 GFKFLDAPVSGGVTGAEAGTLTFMVGGDKQVLNSADPILMKMGANVLHCGDSGAGQIAKL 192
Query: 509 TNNMLMGITGMATAECMNMGIKMGLEPKVLLDVLNNSSARSWSTEVYCPVPGLVPTAPSS 330
NN+++ IT + T E MN+GIKMGL+PK L ++N S+ RSWS++ Y PVPGL+ P S
Sbjct: 193 CNNLILAITMIGTCEGMNLGIKMGLDPKTLASIINVSTGRSWSSQTYNPVPGLIEKIPPS 252
Query: 329 RNYDGGFKNELMVKDLELASGMALGIRSPIPLGAVAXQLYRIVQSRGYGQKDFSFVFQLL 150
+Y GGF L+ KDL LA G+AL +P+PL A A Q+YR + GYG KDF+ V+Q L
Sbjct: 253 NDYKGGFAVNLVAKDLGLAEGVALLCNAPVPLTAAAHQIYRALSCNGYGNKDFASVYQFL 312
Query: 149 K 147
K
Sbjct: 313 K 313
>UniRef50_Q9V8M5 Cluster: Probable 3-hydroxyisobutyrate
dehydrogenase, mitochondrial precursor; n=4;
Diptera|Rep: Probable 3-hydroxyisobutyrate
dehydrogenase, mitochondrial precursor - Drosophila
melanogaster (Fruit fly)
Length = 324
Score = 189 bits (460), Expect = 9e-47
Identities = 84/184 (45%), Positives = 125/184 (67%)
Frame = -3
Query: 692 KGLGFTXAPVXGGVMGAQNVTXAFMAGGXKEDFERSLXLLKVMGXKQFHCGQIGSGQVAK 513
KG F APV GGV GA+ T FM GG + ++ +L+ MG K HCG G GQ AK
Sbjct: 137 KGARFIDAPVSGGVPGAEQATLTFMVGGTEAEYNAVKAVLECMGKKITHCGVYGMGQAAK 196
Query: 512 LTNNMLMGITGMATAECMNMGIKMGLEPKVLLDVLNNSSARSWSTEVYCPVPGLVPTAPS 333
L NNM++ I+ + +E MN+ ++ GL+ V +++N+S+ R W++E+Y PVPG+ P+AP+
Sbjct: 197 LCNNMMLAISMIGVSEAMNLAVRQGLDANVFAEIINSSTGRCWASEIYNPVPGVCPSAPA 256
Query: 332 SRNYDGGFKNELMVKDLELASGMALGIRSPIPLGAVAXQLYRIVQSRGYGQKDFSFVFQL 153
+R+Y GGF + L+ KDL LASG+A SPIPLG++A ++Y+ + +G G KDFS V+ L
Sbjct: 257 NRDYAGGFSSALITKDLGLASGVANASNSPIPLGSLAHKVYQSLCDKGLGNKDFSVVYDL 316
Query: 152 LKEE 141
+K+E
Sbjct: 317 MKKE 320
>UniRef50_Q399N0 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=72;
cellular organisms|Rep: 3-hydroxyisobutyrate
dehydrogenase - Burkholderia sp. (strain 383)
(Burkholderia cepacia (strain ATCC 17760/ NCIB 9086 /
R18194))
Length = 299
Score = 184 bits (449), Expect = 2e-45
Identities = 89/179 (49%), Positives = 117/179 (65%)
Frame = -3
Query: 689 GLGFTXAPVXGGVMGAQNVTXAFMAGGXKEDFERSLXLLKVMGXKQFHCGQIGSGQVAKL 510
G F APV GG GA T FM GG DFER +L MG HCG G GQVAK+
Sbjct: 112 GGAFVDAPVSGGTGGAAAGTLTFMVGGSDADFERVKPVLAGMGKNIVHCGATGMGQVAKV 171
Query: 509 TNNMLMGITGMATAECMNMGIKMGLEPKVLLDVLNNSSARSWSTEVYCPVPGLVPTAPSS 330
NN+++GI+ A +E M++G+ +G++PKVL ++N S+ R WS++ Y P PG++ TAPSS
Sbjct: 172 CNNLVLGISMAAVSEAMSLGVALGIDPKVLAGIVNTSTGRCWSSDTYNPYPGVIDTAPSS 231
Query: 329 RNYDGGFKNELMVKDLELASGMALGIRSPIPLGAVAXQLYRIVQSRGYGQKDFSFVFQL 153
R Y GGF +LM+KDL LA+ A R P+ LGA+A QLY+ + SRG GQ DFS V +L
Sbjct: 232 RGYSGGFGTDLMLKDLGLANDAAKQARQPVYLGALAQQLYQTMSSRGDGQLDFSAVIRL 290
>UniRef50_Q54CX6 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=3;
cellular organisms|Rep: 3-hydroxyisobutyrate
dehydrogenase - Dictyostelium discoideum AX4
Length = 321
Score = 182 bits (444), Expect = 8e-45
Identities = 85/181 (46%), Positives = 119/181 (65%)
Frame = -3
Query: 668 PVXGGVMGAQNVTXAFMAGGXKEDFERSLXLLKVMGXKQFHCGQIGSGQVAKLTNNMLMG 489
PV GG GA+ T FM GG ++DF + L+ MG HCG +G+GQVAK+ NN+++G
Sbjct: 141 PVSGGTGGAEAGTLTFMVGGSEQDFNTAKTYLECMGKNIVHCGDVGTGQVAKVCNNLVLG 200
Query: 488 ITGMATAECMNMGIKMGLEPKVLLDVLNNSSARSWSTEVYCPVPGLVPTAPSSRNYDGGF 309
I+ +A +E MN+G+K G++PK L + N SSAR W++E+Y P PG++ T+P+SR Y GGF
Sbjct: 201 ISMIAVSEAMNLGVKQGMDPKKLAGIFNTSSARCWTSELYNPCPGVIETSPASRGYTGGF 260
Query: 308 KNELMVKDLELASGMALGIRSPIPLGAVAXQLYRIVQSRGYGQKDFSFVFQLLKEENXN* 129
+ LM KDL LA A I P+ LG A QLY ++ ++G GQKDFS V+ L + N
Sbjct: 261 GSALMTKDLGLAVDSAKSIGEPLLLGNSAHQLYTLLVAKGDGQKDFSVVYDFLNKNFKNS 320
Query: 128 N 126
N
Sbjct: 321 N 321
>UniRef50_Q7NWA9 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=7;
Proteobacteria|Rep: 3-hydroxyisobutyrate dehydrogenase -
Chromobacterium violaceum
Length = 296
Score = 169 bits (410), Expect = 1e-40
Identities = 83/177 (46%), Positives = 111/177 (62%)
Frame = -3
Query: 692 KGLGFTXAPVXGGVMGAQNVTXAFMAGGXKEDFERSLXLLKVMGXKQFHCGQIGSGQVAK 513
KGL APV GG GA T F+ GG ED + +L+ MG FH G G+GQ AK
Sbjct: 112 KGLSMLDAPVSGGTAGAAAGTLTFIVGGAAEDLAHARPVLEAMGKNIFHAGGAGAGQTAK 171
Query: 512 LTNNMLMGITGMATAECMNMGIKMGLEPKVLLDVLNNSSARSWSTEVYCPVPGLVPTAPS 333
+ NNML+GI TAE + +G+K GL+PKVL ++++ SS R+W+TE+Y P PG++ P+
Sbjct: 172 ICNNMLLGILMAGTAEALALGVKNGLDPKVLSEIISKSSGRNWATELYNPWPGVMDNTPA 231
Query: 332 SRNYDGGFKNELMVKDLELASGMALGIRSPIPLGAVAXQLYRIVQSRGYGQKDFSFV 162
SR Y GGF +ELM+KDL LA AL + PLGA+A LY +G G+ DFS +
Sbjct: 232 SRGYAGGFMSELMLKDLGLAEETALQSHAANPLGALARNLYEEHVHQGNGKLDFSSI 288
>UniRef50_Q83D20 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=9;
Proteobacteria|Rep: 3-hydroxyisobutyrate dehydrogenase -
Coxiella burnetii
Length = 297
Score = 156 bits (379), Expect = 6e-37
Identities = 73/186 (39%), Positives = 112/186 (60%)
Frame = -3
Query: 695 RKGLGFTXAPVXGGVMGAQNVTXAFMAGGXKEDFERSLXLLKVMGXKQFHCGQIGSGQVA 516
++G+ APV GGV A+ FM GG KEDFER+ +L ++G K + G G+G A
Sbjct: 111 KRGISMLDAPVSGGVAAAEAAGLTFMVGGEKEDFERAKRVLGILGKKIIYAGSDGAGAAA 170
Query: 515 KLTNNMLMGITGMATAECMNMGIKMGLEPKVLLDVLNNSSARSWSTEVYCPVPGLVPTAP 336
K+ NNML+GI+ +A +E + K+GL+P+ L ++ +N+S WS YCP PG++ P
Sbjct: 171 KICNNMLLGISMIAVSEAFVLADKLGLDPQKLFEISSNASGECWSLTHYCPWPGILKDVP 230
Query: 335 SSRNYDGGFKNELMVKDLELASGMALGIRSPIPLGAVAXQLYRIVQSRGYGQKDFSFVFQ 156
SS Y GF ++M+KDL L+ A ++ PLG A +LY+ +G+ DFS +
Sbjct: 231 SSHEYKPGFTAKMMLKDLNLSQAAASDAKANTPLGKRATELYQQFVDSDHGEVDFSAIIN 290
Query: 155 LLKEEN 138
LLK+++
Sbjct: 291 LLKDKS 296
>UniRef50_Q2UHA9 Cluster: Predicted dehydrogenase; n=16;
Pezizomycotina|Rep: Predicted dehydrogenase -
Aspergillus oryzae
Length = 363
Score = 155 bits (377), Expect = 1e-36
Identities = 84/184 (45%), Positives = 114/184 (61%), Gaps = 3/184 (1%)
Frame = -3
Query: 680 FTXAPVXGGVMGAQNVTXAFMAGGXKEDFE---RSLXLLKVMGXKQFHCGQIGSGQVAKL 510
F AP+ GGV+GA+ T +FM G + E R +L +MG K +H G G+G AKL
Sbjct: 177 FVDAPMSGGVVGARAGTLSFMFGASSQTGELVDRVQSVLMLMGKKAWHMGNSGTGVSAKL 236
Query: 509 TNNMLMGITGMATAECMNMGIKMGLEPKVLLDVLNNSSARSWSTEVYCPVPGLVPTAPSS 330
NN L+ I +ATAE MN+GI+ GL+PKVL D++N S+ R W E+ PVPG+V TAP+S
Sbjct: 237 ANNYLLAINNIATAEVMNLGIRCGLDPKVLADMINTSTGRCWPMEINNPVPGVVETAPAS 296
Query: 329 RNYDGGFKNELMVKDLELASGMALGIRSPIPLGAVAXQLYRIVQSRGYGQKDFSFVFQLL 150
R Y GGF LM KDL LA A +P+ L A +Y+ V+ G KDFS V++ L
Sbjct: 297 REYAGGFGISLMNKDLRLAISAAEESGTPLALADKARGVYKAVEDEHRG-KDFSVVYKWL 355
Query: 149 KEEN 138
+E++
Sbjct: 356 QEQS 359
>UniRef50_UPI00015B4162 Cluster: PREDICTED: similar to MGC108315
protein; n=1; Nasonia vitripennis|Rep: PREDICTED:
similar to MGC108315 protein - Nasonia vitripennis
Length = 276
Score = 154 bits (373), Expect = 3e-36
Identities = 68/140 (48%), Positives = 97/140 (69%)
Frame = -3
Query: 557 KQFHCGQIGSGQVAKLTNNMLMGITGMATAECMNMGIKMGLEPKVLLDVLNNSSARSWST 378
K HCG G GQVAK+ NNML+ I+ + +E +++G K+GL+PK+L D++N S+ R WS+
Sbjct: 134 KAVHCGDTGMGQVAKICNNMLLAISMIGVSEALSLGEKLGLDPKILTDIVNTSTGRCWSS 193
Query: 377 EVYCPVPGLVPTAPSSRNYDGGFKNELMVKDLELASGMALGIRSPIPLGAVAXQLYRIVQ 198
EV PVPG+ PT PSS +Y GGF L+ KDL LA A +SPI LG+++ Q+YR ++
Sbjct: 194 EVNNPVPGISPTVPSSNDYAGGFGTSLIAKDLGLAQAAATRAKSPIALGSLSHQIYRTME 253
Query: 197 SRGYGQKDFSFVFQLLKEEN 138
+ G G KDFS V+ ++ EN
Sbjct: 254 AHGLGGKDFSVVYPFIRGEN 273
>UniRef50_P28811 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=72;
Proteobacteria|Rep: 3-hydroxyisobutyrate dehydrogenase -
Pseudomonas aeruginosa
Length = 298
Score = 153 bits (371), Expect = 6e-36
Identities = 76/163 (46%), Positives = 104/163 (63%)
Frame = -3
Query: 692 KGLGFTXAPVXGGVMGAQNVTXAFMAGGXKEDFERSLXLLKVMGXKQFHCGQIGSGQVAK 513
KGL APV GGV GA+ T +F+ GG E F R+ +L+ MG FH G G+GQVAK
Sbjct: 112 KGLTLLDAPVSGGVGGARAGTLSFIVGGPAEGFARARPVLENMGRNIFHAGDHGAGQVAK 171
Query: 512 LTNNMLMGITGMATAECMNMGIKMGLEPKVLLDVLNNSSARSWSTEVYCPVPGLVPTAPS 333
+ NNML+GI TAE + +G+K GL+P VL +V+ SS +W+ +Y P PG++P AP+
Sbjct: 172 ICNNMLLGILMAGTAEALALGVKNGLDPAVLSEVMKQSSGGNWALNLYNPWPGVMPQAPA 231
Query: 332 SRNYDGGFKNELMVKDLELASGMALGIRSPIPLGAVAXQLYRI 204
S Y GGF+ LM KDL LA A +++ PLGA+A L+ +
Sbjct: 232 SNGYAGGFQVRLMNKDLGLALANAQAVQASTPLGALARNLFSL 274
>UniRef50_Q9A8J9 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=24;
Alphaproteobacteria|Rep: 3-hydroxyisobutyrate
dehydrogenase - Caulobacter crescentus (Caulobacter
vibrioides)
Length = 298
Score = 153 bits (370), Expect = 8e-36
Identities = 74/181 (40%), Positives = 102/181 (56%)
Frame = -3
Query: 689 GLGFTXAPVXGGVMGAQNVTXAFMAGGXKEDFERSLXLLKVMGXKQFHCGQIGSGQVAKL 510
G F APV GG+M A+ T AFM G DF L M H G G+GQ AK+
Sbjct: 111 GFRFADAPVSGGIMAAEAGTLAFMVGCEASDFAAVEAALAPMSRVTIHAGDHGAGQAAKI 170
Query: 509 TNNMLMGITGMATAECMNMGIKMGLEPKVLLDVLNNSSARSWSTEVYCPVPGLVPTAPSS 330
NNML+G++ + T E + K+GL ++ + SS + WS YCPVPG+ P P+
Sbjct: 171 CNNMLLGVSMLGTCEAFALAEKLGLAADRFFEIASKSSGQCWSITSYCPVPGVGPQTPAD 230
Query: 329 RNYDGGFKNELMVKDLELASGMALGIRSPIPLGAVAXQLYRIVQSRGYGQKDFSFVFQLL 150
R Y+GGF + +M+KDL+LA A + P+GA A LY + + G+G KDFS V +LL
Sbjct: 231 RGYEGGFASAMMLKDLKLAQEAAAKAGASTPMGAQAEALYALFDANGFGGKDFSAVIELL 290
Query: 149 K 147
+
Sbjct: 291 R 291
>UniRef50_A7UBP6 Cluster: Putative 3-hydroxyisobutyrate
dehydrogenase; n=1; Paracoccus methylutens|Rep: Putative
3-hydroxyisobutyrate dehydrogenase - Paracoccus
methylutens
Length = 302
Score = 152 bits (369), Expect = 1e-35
Identities = 75/182 (41%), Positives = 112/182 (61%)
Frame = -3
Query: 692 KGLGFTXAPVXGGVMGAQNVTXAFMAGGXKEDFERSLXLLKVMGXKQFHCGQIGSGQVAK 513
+G+ APV GGVMGA+ T FM GG ED ER+ +L+ MG + FH G+ G GQ AK
Sbjct: 112 RGIAVLDAPVSGGVMGAEAGTLTFMVGGSAEDLERARPVLEAMGRRIFHAGEPGVGQAAK 171
Query: 512 LTNNMLMGITGMATAECMNMGIKMGLEPKVLLDVLNNSSARSWSTEVYCPVPGLVPTAPS 333
L NN+L GI+ +A +E + +GL+ + + ++ S+ +S Y PVPGLVP PS
Sbjct: 172 LCNNLLAGISMIAVSEAFALARHLGLDARKMQEISAVSTGGCFSLTNYPPVPGLVPNVPS 231
Query: 332 SRNYDGGFKNELMVKDLELASGMALGIRSPIPLGAVAXQLYRIVQSRGYGQKDFSFVFQL 153
SR Y GF ++LM+KDL+LA A+ + +PLG +A LY + G+ + D+S + +L
Sbjct: 232 SREYRNGFASQLMLKDLKLAQQAAIQSGTALPLGGLAAALYGMFCQAGHSELDYSAIIKL 291
Query: 152 LK 147
++
Sbjct: 292 IE 293
>UniRef50_Q22B54 Cluster: 3-hydroxyisobutyrate dehydrogenase family
protein; n=1; Tetrahymena thermophila SB210|Rep:
3-hydroxyisobutyrate dehydrogenase family protein -
Tetrahymena thermophila SB210
Length = 316
Score = 151 bits (365), Expect = 3e-35
Identities = 75/178 (42%), Positives = 111/178 (62%), Gaps = 1/178 (0%)
Frame = -3
Query: 680 FTXAPVXGGVMGAQNVTXAFMAGGX-KEDFERSLXLLKVMGXKQFHCGQIGSGQVAKLTN 504
+ APV GGV A T FM G KE F+ LL+ MG +C + G+G +AK+ N
Sbjct: 132 YIDAPVSGGVGAATAGTLTFMVGAENKELFQECKNLLQHMGKNIANCEKPGAGSIAKICN 191
Query: 503 NMLMGITGMATAECMNMGIKMGLEPKVLLDVLNNSSARSWSTEVYCPVPGLVPTAPSSRN 324
NM +GI +A AE +++G K+G++PKVL ++N +S R WS+EVY P PG++ P+S+
Sbjct: 192 NMALGIEMIAVAEAISLGKKLGIDPKVLSSIMNTASGRCWSSEVYNPCPGVLENVPASKG 251
Query: 323 YDGGFKNELMVKDLELASGMALGIRSPIPLGAVAXQLYRIVQSRGYGQKDFSFVFQLL 150
Y+GGF ELM+KDL LA+ A + +PLG A +Y+ + G +KDF+ V+ +L
Sbjct: 252 YEGGFACELMLKDLGLAADAAKQASADVPLGNHAKDIYQKLVELGLNRKDFAIVYDVL 309
>UniRef50_Q9SUC0 Cluster: Probable 3-hydroxyisobutyrate
dehydrogenase, mitochondrial precursor; n=13;
Magnoliophyta|Rep: Probable 3-hydroxyisobutyrate
dehydrogenase, mitochondrial precursor - Arabidopsis
thaliana (Mouse-ear cress)
Length = 347
Score = 147 bits (357), Expect = 3e-34
Identities = 69/172 (40%), Positives = 107/172 (62%)
Frame = -3
Query: 671 APVXGGVMGAQNVTXAFMAGGXKEDFERSLXLLKVMGXKQFHCGQIGSGQVAKLTNNMLM 492
APV GGV+ A+ T FM GG ++ + + +L+ MG +CG G+G AK+ NN+ M
Sbjct: 167 APVSGGVLAAEAGTLTFMVGGPEDAYLAARPILQSMGRTSIYCGGSGNGSAAKICNNLAM 226
Query: 491 GITGMATAECMNMGIKMGLEPKVLLDVLNNSSARSWSTEVYCPVPGLVPTAPSSRNYDGG 312
++ + T+E + +G +G+ L +VLN SS R WS++ Y PVPG++ PSSR+Y+GG
Sbjct: 227 AVSMLGTSEALALGQSLGISASTLTEVLNTSSGRCWSSDAYNPVPGVMKGVPSSRDYNGG 286
Query: 311 FKNELMVKDLELASGMALGIRSPIPLGAVAXQLYRIVQSRGYGQKDFSFVFQ 156
F ++LM KDL LA+ A + PL + A ++Y+ + G+ KDFS VF+
Sbjct: 287 FASKLMAKDLNLAAASAEEVGHKSPLISKAQEIYKKMCEEGHETKDFSCVFR 338
>UniRef50_Q0K0E2 Cluster: 3-Hydroxyisobutyrate dehydrogenase; n=1;
Ralstonia eutropha H16|Rep: 3-Hydroxyisobutyrate
dehydrogenase - Ralstonia eutropha (strain ATCC 17699 /
H16 / DSM 428 / Stanier 337)(Cupriavidus necator (strain
ATCC 17699 / H16 / DSM 428 / Stanier337))
Length = 299
Score = 146 bits (354), Expect = 7e-34
Identities = 67/181 (37%), Positives = 109/181 (60%)
Frame = -3
Query: 689 GLGFTXAPVXGGVMGAQNVTXAFMAGGXKEDFERSLXLLKVMGXKQFHCGQIGSGQVAKL 510
G APV GG GA+ FM GG + F+R+ +L+ MG + F+ G G+GQ+AKL
Sbjct: 113 GFAMLDAPVAGGQAGAREARLTFMVGGARTAFDRAEPVLRQMGARIFYAGASGNGQIAKL 172
Query: 509 TNNMLMGITGMATAECMNMGIKMGLEPKVLLDVLNNSSARSWSTEVYCPVPGLVPTAPSS 330
NN++ ++ +E +G K+G++ + + D++ S+ + W+ CPVPG VP++P+S
Sbjct: 173 CNNLIACVSSAVVSEAFILGSKLGMDYQTMYDIITQSTGQCWTLSHNCPVPGPVPSSPAS 232
Query: 329 RNYDGGFKNELMVKDLELASGMALGIRSPIPLGAVAXQLYRIVQSRGYGQKDFSFVFQLL 150
R+Y GF +LM+KDL L + A + + P GA A QLYR + G G +D++ V +L+
Sbjct: 233 RDYVPGFAADLMLKDLSLVASAASEVGAATPFGARAIQLYRQLSESGLGARDWTVVARLI 292
Query: 149 K 147
+
Sbjct: 293 E 293
>UniRef50_Q6C351 Cluster: Yarrowia lipolytica chromosome F of strain
CLIB122 of Yarrowia lipolytica; n=1; Yarrowia
lipolytica|Rep: Yarrowia lipolytica chromosome F of
strain CLIB122 of Yarrowia lipolytica - Yarrowia
lipolytica (Candida lipolytica)
Length = 334
Score = 141 bits (342), Expect = 2e-32
Identities = 76/185 (41%), Positives = 113/185 (61%), Gaps = 4/185 (2%)
Frame = -3
Query: 680 FTXAPVXGGVMGAQNVTXAFMAGGXKED---FERSLXLLKVMGXKQFHCGQIGSGQVAKL 510
F APV GGV+GA+ T FM G K+ +++ LLK+MG + +CG G G AKL
Sbjct: 149 FVDAPVSGGVVGAEKGTLTFMVGCNKDKQQVYKQVEELLKLMGGRIVNCGTQGQGLAAKL 208
Query: 509 TNNMLMGITGMATAECMNMGIKMGLEPKVLLDVLNNSSARSWSTEVYCPVPGLVPTAPSS 330
NN L+ +T +ATAE ++ K+G + K+ D++N+SS RSWS+EV PVPG+ P PSS
Sbjct: 209 ANNYLLAVTNVATAEAFHLAEKLGCDLKLFSDIVNSSSGRSWSSEVNNPVPGVNPATPSS 268
Query: 329 RNYDGGFKNELMVKDLELASGMALGIRSPIPLGAVAXQLYR-IVQSRGYGQKDFSFVFQL 153
R+Y GGF LM KDL LA +A S + + ++Y+ I + Y KD S +++
Sbjct: 269 RDYVGGFGINLMRKDLGLAIDVAKQSGSSMLVADKTYEVYQNIEKGDNYQGKDMSVIYKF 328
Query: 152 LKEEN 138
L++++
Sbjct: 329 LQDQD 333
>UniRef50_A0QSJ0 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=3;
Bacteria|Rep: 3-hydroxyisobutyrate dehydrogenase -
Mycobacterium smegmatis (strain ATCC 700084 / mc(2)155)
Length = 290
Score = 139 bits (337), Expect = 7e-32
Identities = 73/182 (40%), Positives = 99/182 (54%)
Frame = -3
Query: 692 KGLGFTXAPVXGGVMGAQNVTXAFMAGGXKEDFERSLXLLKVMGXKQFHCGQIGSGQVAK 513
KG APV GGV GA T AFM GG + ER+ +L M K HCG G+GQ AK
Sbjct: 109 KGHAQLDAPVSGGVKGATAGTLAFMVGGEDDAVERARPILDPMAGKIIHCGGSGTGQAAK 168
Query: 512 LTNNMLMGITGMATAECMNMGIKMGLEPKVLLDVLNNSSARSWSTEVYCPVPGLVPTAPS 333
L NNM++ + +A E + K+GL + L DV+ ++ WS CPVPG VPT+P+
Sbjct: 169 LCNNMVLAVQQIAIGEAFVLAEKLGLSAQSLFDVITGATGNCWSVHTNCPVPGPVPTSPA 228
Query: 332 SRNYDGGFKNELMVKDLELASGMALGIRSPIPLGAVAXQLYRIVQSRGYGQKDFSFVFQL 153
+ ++ GF LM KDL LA + PLG+ A ++Y + KDFS V +L
Sbjct: 229 NNDFKPGFATSLMNKDLGLAMAAVSSTGASAPLGSHAAEIYAKFNEE-HADKDFSAVIEL 287
Query: 152 LK 147
L+
Sbjct: 288 LR 289
>UniRef50_A0C2T7 Cluster: Chromosome undetermined scaffold_145,
whole genome shotgun sequence; n=2; Paramecium
tetraurelia|Rep: Chromosome undetermined scaffold_145,
whole genome shotgun sequence - Paramecium tetraurelia
Length = 299
Score = 139 bits (336), Expect = 1e-31
Identities = 68/177 (38%), Positives = 106/177 (59%)
Frame = -3
Query: 680 FTXAPVXGGVMGAQNVTXAFMAGGXKEDFERSLXLLKVMGXKQFHCGQIGSGQVAKLTNN 501
+ APV G V A+ T FM G KE +E+ +LK MG F+CG+IG GQ+AK+ N
Sbjct: 120 YADAPVSGSVSEAKLGTITFMVGAEKELYEKISPILKEMGKNIFNCGKIGEGQIAKMCGN 179
Query: 500 MLMGITGMATAECMNMGIKMGLEPKVLLDVLNNSSARSWSTEVYCPVPGLVPTAPSSRNY 321
M + I ++ E + +G MG++P +L +++ SS+R W+ + Y P PG++P PS+++Y
Sbjct: 180 MALAIQMISVCEALALGKNMGMDPAMLSSIMSVSSSRCWTVDTYNPAPGVMPNVPSNKDY 239
Query: 320 DGGFKNELMVKDLELASGMALGIRSPIPLGAVAXQLYRIVQSRGYGQKDFSFVFQLL 150
DGGF ELM+KDL + + + LG A Q+Y + G+KDF+ V++ L
Sbjct: 240 DGGFMVELMLKDLGIGIEASRLSGTDTQLGQHAYQIYNKLNEH-LGKKDFAIVYKEL 295
>UniRef50_A7JGH8 Cluster: Predicted protein; n=1; Francisella
tularensis subsp. novicida GA99-3549|Rep: Predicted
protein - Francisella tularensis subsp. novicida
GA99-3549
Length = 293
Score = 134 bits (325), Expect = 2e-30
Identities = 68/182 (37%), Positives = 100/182 (54%), Gaps = 1/182 (0%)
Frame = -3
Query: 695 RKGLGFTXAPVXGGVMGAQNVTXAFMAGGXKEDFERSLXLLKVMGXKQFHCGQIGSGQVA 516
+ L APV GG++GAQN T FM GG KE FER L MG K H G G G +
Sbjct: 111 QNNLHMLDAPVSGGIIGAQNATLTFMVGGDKEIFERCKNLFNSMGKKYLHVGDNGKGLII 170
Query: 515 KLTNNMLMGITGMATAECMNMGIKMGLEPKVLLDVLNNSSARSWSTEVYCPVPGLVPTAP 336
KL NNML+GI +A +E N K G+ K D++ +S+ SW+ P+P ++ P
Sbjct: 171 KLINNMLLGINMIAASEACNFAEKTGINLKTFYDIVASSTGSSWAFNKNFPMPDIIENVP 230
Query: 335 SSRNYDGGFKNELMVKDLELASGMALGIRSPIPLGAVAXQLY-RIVQSRGYGQKDFSFVF 159
++ +Y GF L++KD+ +A A + LG +A ++Y R++ S +KDFS V
Sbjct: 231 ANNDYKPGFGAPLIMKDINIAVETAQDYNINLKLGLLAKEIYERMINSEELNKKDFSAVI 290
Query: 158 QL 153
++
Sbjct: 291 KV 292
>UniRef50_P63936 Cluster: Probable 3-hydroxyisobutyrate
dehydrogenase; n=25; Bacteria|Rep: Probable
3-hydroxyisobutyrate dehydrogenase - Mycobacterium bovis
Length = 294
Score = 132 bits (318), Expect = 1e-29
Identities = 67/175 (38%), Positives = 95/175 (54%)
Frame = -3
Query: 671 APVXGGVMGAQNVTXAFMAGGXKEDFERSLXLLKVMGXKQFHCGQIGSGQVAKLTNNMLM 492
APV GGV GA T AFM GG + R+ +L+ M K HCG G+GQ AK+ NNM++
Sbjct: 116 APVSGGVKGAAAATLAFMVGGDESTLRRARPVLEPMAGKIIHCGAAGAGQAAKVCNNMVL 175
Query: 491 GITGMATAECMNMGIKMGLEPKVLLDVLNNSSARSWSTEVYCPVPGLVPTAPSSRNYDGG 312
+ +A AE + K+GL + L DV+ ++ W+ CPVPG VPT+P++ ++ G
Sbjct: 176 AVQQIAIAEAFVLAEKLGLSAQSLFDVITGATGNCWAVHTNCPVPGPVPTSPANNDFKPG 235
Query: 311 FKNELMVKDLELASGMALGIRSPIPLGAVAXQLYRIVQSRGYGQKDFSFVFQLLK 147
F LM KDL LA + PLG+ A +Y + + DFS V L+
Sbjct: 236 FSTALMNKDLGLAMDAVAATGATAPLGSHAADIYAKF-AADHADLDFSAVIHTLR 289
>UniRef50_Q4PCH4 Cluster: Putative uncharacterized protein; n=1;
Ustilago maydis|Rep: Putative uncharacterized protein -
Ustilago maydis (Smut fungus)
Length = 366
Score = 129 bits (312), Expect = 8e-29
Identities = 69/180 (38%), Positives = 99/180 (55%), Gaps = 6/180 (3%)
Frame = -3
Query: 671 APVXGGVMGAQNVTXAFMAGGXKED-FERSLXLLKVMGXKQFHCGQIGSGQVAKLTNNML 495
APV GGV+GA T +FM G F + L +MG + HCG+ G+G +AK+ NN+L
Sbjct: 171 APVSGGVVGANAATLSFMVGSDSSTTFASAEPYLSLMGSRAVHCGKNGNGLIAKIANNLL 230
Query: 494 MGITGMATAECMNMGIKMGLEPKVLLDVLNNSSARSWSTEVYCPVPGLVP----TAPSSR 327
+GI+ + E M +G GL P VL ++N S+ + WS+EV P PG + + P+ R
Sbjct: 231 LGISMLGVTEAMLLGTAHGLPPAVLAGIINTSTGKCWSSEVNNPCPGALEGTKYSPPADR 290
Query: 326 NYDGGFKNELMVKDLELASGMALGIRSPIPLGAVAXQLYRIVQSRG-YGQKDFSFVFQLL 150
+Y GGF LM KDL+LA A P PLG + +Y + + KDF+ F+ L
Sbjct: 291 DYQGGFAARLMAKDLKLAMNTAKLQGVPTPLGQLTSSIYEALGGNDEFKDKDFAVAFKAL 350
>UniRef50_Q0URA2 Cluster: Putative uncharacterized protein; n=1;
Phaeosphaeria nodorum|Rep: Putative uncharacterized
protein - Phaeosphaeria nodorum (Septoria nodorum)
Length = 325
Score = 124 bits (299), Expect = 3e-27
Identities = 77/187 (41%), Positives = 100/187 (53%), Gaps = 4/187 (2%)
Frame = -3
Query: 692 KGLGFTXAPVXGGVMGAQNVTXAFMAGGX-KEDFERSLXLLKVMGXKQ--FHCGQIGSGQ 522
+ L F APV GG MGAQ+ T AFMAG K F R L MG F CG IG+G
Sbjct: 135 ENLTFVDAPVSGGPMGAQDGTLAFMAGANNKAIFPRVKGYLSHMGKPDAIFLCGDIGAGT 194
Query: 521 VAKLTNNMLMGITGMATAECMNMGIKMGLEPKVLLDVLNNSSARSWSTEVYCPVPGLVPT 342
K+ NN L IT +A +E +N+G KMGL+ +L DV+N S + W T PVPG+
Sbjct: 195 AFKVINNYLSAITSLAASEALNIGTKMGLDVALLTDVINVSGGQCWVTSKSNPVPGVQAN 254
Query: 341 APSSRNYDGGFKNELMVKDLELASGMALGIRSPIPLGAVAXQLYRIVQSRG-YGQKDFSF 165
PSSR+Y+GGF+ EL K L + S +A + + L + S G Y KD
Sbjct: 255 VPSSRDYEGGFRIELCRKVLGMGSELAEMVGARTILDKPTLAAFDEAMSDGRYKGKDARV 314
Query: 164 VFQLLKE 144
V++ L E
Sbjct: 315 VYKWLNE 321
>UniRef50_A1QPH6 Cluster: 3-hydroxyisobutyrate dehydrogenase mmsB;
n=5; Mycobacterium|Rep: 3-hydroxyisobutyrate
dehydrogenase mmsB - Mycobacterium tuberculosis (strain
F11)
Length = 315
Score = 114 bits (275), Expect = 2e-24
Identities = 52/126 (41%), Positives = 74/126 (58%)
Frame = -3
Query: 671 APVXGGVMGAQNVTXAFMAGGXKEDFERSLXLLKVMGXKQFHCGQIGSGQVAKLTNNMLM 492
APV GGV GA T AFM GG + R+ +L+ M K HCG G+GQ AK+ NNM++
Sbjct: 116 APVSGGVKGAAAATLAFMVGGDESTLRRARPVLEPMAGKIIHCGAAGAGQAAKVCNNMVL 175
Query: 491 GITGMATAECMNMGIKMGLEPKVLLDVLNNSSARSWSTEVYCPVPGLVPTAPSSRNYDGG 312
+ +A AE + K+GL + L DV+ ++ W+ CPVPG VPT+P++ ++ G
Sbjct: 176 AVQQIAIAEAFVLAEKLGLSAQSLFDVITGATGNCWAVHTNCPVPGPVPTSPANNDFKPG 235
Query: 311 FKNELM 294
F LM
Sbjct: 236 FSTALM 241
>UniRef50_Q0C8I2 Cluster: Predicted protein; n=3;
Pezizomycotina|Rep: Predicted protein - Aspergillus
terreus (strain NIH 2624)
Length = 320
Score = 113 bits (273), Expect = 4e-24
Identities = 64/159 (40%), Positives = 90/159 (56%), Gaps = 2/159 (1%)
Frame = -3
Query: 680 FTXAPVXGGVMGAQNVTXAFMAGGXKEDFERSLXL--LKVMGXKQFHCGQIGSGQVAKLT 507
F APV GGV+GAQ AF G K D L L++MG + CG G AKL
Sbjct: 130 FYDAPVSGGVLGAQKGAIAFFLGCAKTDPNLPLLTDTLRLMGKEVIPCGGPSLGLSAKLC 189
Query: 506 NNMLMGITGMATAECMNMGIKMGLEPKVLLDVLNNSSARSWSTEVYCPVPGLVPTAPSSR 327
NN L G+ +A +E +N+G++ GL+P+VL V +A++ + + P PG+VP APSS+
Sbjct: 190 NNYLSGLIAIANSEALNIGMRAGLDPRVLSSVFAAGTAQNAICDRFNPCPGVVPDAPSSK 249
Query: 326 NYDGGFKNELMVKDLELASGMALGIRSPIPLGAVAXQLY 210
+Y GFK +LM KD LA MA + + + LG + Y
Sbjct: 250 DYRTGFKIQLMRKDFALAVAMAEQVGARLVLGEAGLKTY 288
>UniRef50_A0GVR3 Cluster: 6-phosphogluconate dehydrogenase,
NAD-binding; n=1; Burkholderia phytofirmans PsJN|Rep:
6-phosphogluconate dehydrogenase, NAD-binding -
Burkholderia phytofirmans PsJN
Length = 311
Score = 111 bits (268), Expect = 2e-23
Identities = 59/163 (36%), Positives = 85/163 (52%), Gaps = 1/163 (0%)
Frame = -3
Query: 689 GLGFTXAPVXGGVMGAQNVTXAFMAGGXKEDFERSLXLLKVMGXKQFHCGQIGSGQVAKL 510
G AP+ GG+ GA T FM GG +E E + L+ MG + H G+ GSG KL
Sbjct: 112 GTQLIDAPLTGGIEGAALATLTFMVGGSEEQLEYARPALQSMGSRIVHAGRFGSGTKLKL 171
Query: 509 TNNMLMGITGMATAECMNMGIKMGLEPKVLLDVLNNSSARSWSTEVYCPVPGLVPTAPSS 330
NNM+ M +E + +G+K+GL+ + + DV+ N + SW Y P+PG+V APSS
Sbjct: 172 VNNMICATNLMVASEALTLGLKLGLDAQPMYDVIANGTGASWVLNTYYPLPGVVDGAPSS 231
Query: 329 RNYD-GGFKNELMVKDLELASGMALGIRSPIPLGAVAXQLYRI 204
R + F M KD+ A A + + PL VA L ++
Sbjct: 232 RGFRMPTFPATGMAKDMRCALEAARSVEAVTPLHNVAESLLKL 274
>UniRef50_A6NVP0 Cluster: Putative uncharacterized protein; n=1;
Bacteroides capillosus ATCC 29799|Rep: Putative
uncharacterized protein - Bacteroides capillosus ATCC
29799
Length = 306
Score = 111 bits (266), Expect = 3e-23
Identities = 58/183 (31%), Positives = 99/183 (54%)
Frame = -3
Query: 692 KGLGFTXAPVXGGVMGAQNVTXAFMAGGXKEDFERSLXLLKVMGXKQFHCGQIGSGQVAK 513
KG+ + APV GGV GA T M G E F + + V+G +H G+ G G K
Sbjct: 116 KGIHYIDAPVSGGVSGAAAGTLTIMVGADDETFNKVKPIFDVLGKNIYHVGEAGGGDAIK 175
Query: 512 LTNNMLMGITGMATAECMNMGIKMGLEPKVLLDVLNNSSARSWSTEVYCPVPGLVPTAPS 333
+ NN+L+G A AE + +G+K GL + + +V++ SS RS++ + +
Sbjct: 176 MVNNLLLGCNMAALAEALTLGVKCGLSVETMKEVISVSSGRSYALD------AKLEKFIM 229
Query: 332 SRNYDGGFKNELMVKDLELASGMALGIRSPIPLGAVAXQLYRIVQSRGYGQKDFSFVFQL 153
+ ++GGF +L KDL LA + + P+P+ A A Q+Y + +++G G++D S V ++
Sbjct: 230 AGQFNGGFAVDLQYKDLGLALEASRDEKVPLPMTAAAVQVYEMARAKGQGREDMSSVVKV 289
Query: 152 LKE 144
++
Sbjct: 290 WED 292
>UniRef50_Q1V2R0 Cluster: MmsB-like protein; n=2; Candidatus
Pelagibacter ubique|Rep: MmsB-like protein - Candidatus
Pelagibacter ubique HTCC1002
Length = 308
Score = 110 bits (264), Expect = 5e-23
Identities = 58/186 (31%), Positives = 95/186 (51%)
Frame = -3
Query: 689 GLGFTXAPVXGGVMGAQNVTXAFMAGGXKEDFERSLXLLKVMGXKQFHCGQIGSGQVAKL 510
G+ APV GGVMGA+ F+ GG E + L +MG K H G GSG K+
Sbjct: 114 GIKMIDAPVTGGVMGARIGKLNFLVGGSDEAVALAKPLFDIMGQKILHAGVQGSGVGVKI 173
Query: 509 TNNMLMGITGMATAECMNMGIKMGLEPKVLLDVLNNSSARSWSTEVYCPVPGLVPTAPSS 330
NNM +GI+ +A +E + + ++ ++ K + +++ +S +W+ Y P+P L PS+
Sbjct: 174 CNNMSLGISMIAASESLMLAKRLKMDIKKVHEIIKAASGNNWAMTNYTPLPNLTDGVPSN 233
Query: 329 RNYDGGFKNELMVKDLELASGMALGIRSPIPLGAVAXQLYRIVQSRGYGQKDFSFVFQLL 150
Y GF +M KDL LA A + + PLG A +++ G D+S + +++
Sbjct: 234 NKYRPGFTASMMRKDLRLAMDAAQSVDASTPLGKAALEIFSKFCDEGDSDTDYSGISKMI 293
Query: 149 KEENXN 132
+ N
Sbjct: 294 GGDAWN 299
>UniRef50_A3I4V2 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=1;
Bacillus sp. B14905|Rep: 3-hydroxyisobutyrate
dehydrogenase - Bacillus sp. B14905
Length = 316
Score = 109 bits (262), Expect = 9e-23
Identities = 64/183 (34%), Positives = 97/183 (53%), Gaps = 1/183 (0%)
Frame = -3
Query: 689 GLGFTXAPVXGGVMGAQNVTXAFMAGGXKEDFERSLXLLKVMGXKQFHCGQIGS-GQVAK 513
GL + APV GGV+GA N T M GG K+D++ + + ++G +H G S G K
Sbjct: 133 GLRYLGAPVSGGVIGAVNATLTIMVGGGKDDYDSASEIFGIVGKNIYHLGLSSSVGTRLK 192
Query: 512 LTNNMLMGITGMATAECMNMGIKMGLEPKVLLDVLNNSSARSWSTEVYCPVPGLVPTAPS 333
L NN+++G A AE + +G KMG++ L +VL+NS +S +Y
Sbjct: 193 LLNNLMIGFYTEAVAETIVLGEKMGIDADTLYEVLSNSYGQS---RIY---ERNYVEYMK 246
Query: 332 SRNYDGGFKNELMVKDLELASGMALGIRSPIPLGAVAXQLYRIVQSRGYGQKDFSFVFQL 153
+ NY GF L++KDL+LA GMA + +G +LY + +GYG+ D S +
Sbjct: 247 NNNYAPGFSTNLLLKDLKLAKGMADEAGVSLRIGEKLVELYSEIAQQGYGENDMSAAYLS 306
Query: 152 LKE 144
LK+
Sbjct: 307 LKD 309
>UniRef50_Q4ZQL5 Cluster: 3-hydroxyisobutyrate dehydrogenase
precursor; n=11; Proteobacteria|Rep:
3-hydroxyisobutyrate dehydrogenase precursor -
Pseudomonas syringae pv. syringae (strain B728a)
Length = 296
Score = 108 bits (260), Expect = 2e-22
Identities = 63/180 (35%), Positives = 95/180 (52%)
Frame = -3
Query: 695 RKGLGFTXAPVXGGVMGAQNVTXAFMAGGXKEDFERSLXLLKVMGXKQFHCGQIGSGQVA 516
+ G+ F APV GG GA + + + G D R++ +L+ M + H GQ G+G VA
Sbjct: 112 KNGIAFIDAPVSGGPKGAATGSMSMVIGAEDADLARAMPVLEGMSGTRVHVGQCGAGNVA 171
Query: 515 KLTNNMLMGITGMATAECMNMGIKMGLEPKVLLDVLNNSSARSWSTEVYCPVPGLVPTAP 336
K+ NNML ++TAE + M + G++P+ LL LN S RS +T+V + PT
Sbjct: 172 KIANNMLAACHLISTAEAVAMAARAGVDPEKLLQGLNAGSGRSGATQV------MFPTWV 225
Query: 335 SSRNYDGGFKNELMVKDLELASGMALGIRSPIPLGAVAXQLYRIVQSRGYGQKDFSFVFQ 156
++ YD GF LM KD+ LAS +A + +PL V QL++ +DF + Q
Sbjct: 226 LNKAYDSGFTMGLMRKDVGLASDLADSLDMDLPLSRVVAQLWQASSETLADNEDFCAIVQ 285
>UniRef50_Q0QLF5 Cluster: 2-hydroxymethyl glutarate dehydrogenase;
n=1; Eubacterium barkeri|Rep: 2-hydroxymethyl glutarate
dehydrogenase - Eubacterium barkeri (Clostridium
barkeri)
Length = 301
Score = 108 bits (259), Expect = 2e-22
Identities = 58/183 (31%), Positives = 99/183 (54%)
Frame = -3
Query: 692 KGLGFTXAPVXGGVMGAQNVTXAFMAGGXKEDFERSLXLLKVMGXKQFHCGQIGSGQVAK 513
KG+ + APV GG GA+ T M G + FE+ +L V+G +H G G+G K
Sbjct: 115 KGIDYVDAPVSGGTKGAEAGTLTIMVGASEAVFEKIQPVLSVIGKDIYHVGDTGAGDAVK 174
Query: 512 LTNNMLMGITGMATAECMNMGIKMGLEPKVLLDVLNNSSARSWSTEVYCPVPGLVPTAPS 333
+ NN+L+G + AE + +G+K GL+P+ + +++ SS RS++ E +
Sbjct: 175 IVNNLLLGCNMASLAEALVLGVKCGLKPETMQEIIGKSSGRSYAME------AKMEKFIM 228
Query: 332 SRNYDGGFKNELMVKDLELASGMALGIRSPIPLGAVAXQLYRIVQSRGYGQKDFSFVFQL 153
S ++ GGF +L KDL LA P+P+ A+A Q++ ++ G G++D S V ++
Sbjct: 229 SGDFAGGFAMDLQHKDLGLALEAGKEGNVPLPMTAMATQIFEGGRAMGLGREDMSAVIKV 288
Query: 152 LKE 144
++
Sbjct: 289 WEQ 291
>UniRef50_Q67QX0 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=1;
Symbiobacterium thermophilum|Rep: 3-hydroxyisobutyrate
dehydrogenase - Symbiobacterium thermophilum
Length = 294
Score = 105 bits (253), Expect = 1e-21
Identities = 65/183 (35%), Positives = 97/183 (53%)
Frame = -3
Query: 692 KGLGFTXAPVXGGVMGAQNVTXAFMAGGXKEDFERSLXLLKVMGXKQFHCGQIGSGQVAK 513
KG+ F APV GG GA+ T M GG + FE L L+V G H G +G+G VAK
Sbjct: 110 KGVQFIDAPVSGGPWGAEAGTLTIMCGGDRAAFEAVLPYLQVEGKAIHHLGPVGAGSVAK 169
Query: 512 LTNNMLMGITGMATAECMNMGIKMGLEPKVLLDVLNNSSARSWSTEVYCPVPGLVPTAPS 333
L NN+L+GI A AE +G K G++PK L ++++N++ S ++ +P V P
Sbjct: 170 LCNNLLVGIHTAAMAEAFVLGTKAGVDPKALYEIISNATGH--SAQIARNIPQFV--FPG 225
Query: 332 SRNYDGGFKNELMVKDLELASGMALGIRSPIPLGAVAXQLYRIVQSRGYGQKDFSFVFQL 153
+D F + + KD+ LA + + LGAV QL ++ GYG D + + +
Sbjct: 226 --KFDAAFSIDHLHKDVALAVELGKDENVRMVLGAVTQQLLAEARALGYGGSDQAALIRP 283
Query: 152 LKE 144
L+E
Sbjct: 284 LEE 286
>UniRef50_Q55702 Cluster: Uncharacterized oxidoreductase slr0229;
n=4; Cyanobacteria|Rep: Uncharacterized oxidoreductase
slr0229 - Synechocystis sp. (strain PCC 6803)
Length = 290
Score = 103 bits (248), Expect = 5e-21
Identities = 62/168 (36%), Positives = 90/168 (53%)
Frame = -3
Query: 692 KGLGFTXAPVXGGVMGAQNVTXAFMAGGXKEDFERSLXLLKVMGXKQFHCGQIGSGQVAK 513
+GL F APV GG +GA N T M GG DFE +L +LK +G K HCG GSGQ K
Sbjct: 116 QGLRFLDAPVTGGDVGAINGTLTIMVGGDISDFEEALPVLKSIGEKIVHCGPSGSGQAVK 175
Query: 512 LTNNMLMGITGMATAECMNMGIKMGLEPKVLLDVLNNSSARSWSTEVYCPVPGLVPTAPS 333
L N +L GI +A AE + + ++G+ P++++D + +A SW+ + L P S
Sbjct: 176 LCNQVLCGIHAIAAAEAIQLSEQLGIAPELVIDTCGSGAAGSWA------LTNLAPKM-S 228
Query: 332 SRNYDGGFKNELMVKDLELASGMALGIRSPIPLGAVAXQLYRIVQSRG 189
++ GF + ++KDL L A P+P +A L+ VQ G
Sbjct: 229 EADFAPGFMVKHLLKDLRLVREAA--ENGPLPGVTLAESLFTSVQLLG 274
>UniRef50_A1SIN3 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=1;
Nocardioides sp. JS614|Rep: 3-hydroxyisobutyrate
dehydrogenase - Nocardioides sp. (strain BAA-499 /
JS614)
Length = 308
Score = 102 bits (245), Expect = 1e-20
Identities = 56/164 (34%), Positives = 82/164 (50%), Gaps = 1/164 (0%)
Frame = -3
Query: 689 GLGFTXAPVXGGVMGAQNVTXAFMAGGXKEDFERSLXLLKVMGXKQFHCGQIGSGQVAKL 510
G+ F APV GGV GA T FM GG + R+ L + MG K G +GQ K+
Sbjct: 116 GIAFLDAPVSGGVGGAAAGTLTFMVGGDEAHVRRAWPLFEAMGKKVVRVGGPSTGQAVKM 175
Query: 509 TNNMLMGITGMATAECMNMGIKMGLEPKVLLDVLNNSSARSWSTEVYCPVPGLVP-TAPS 333
N M+ + +A AE ++ K+G+ PK+L +V+ +SS W+ CP P +V + +
Sbjct: 176 CNQMIYASSLVAVAEAFSLADKLGVAPKMLFEVVTSSSGDCWAIRNSCPWPDVVEGGSAA 235
Query: 332 SRNYDGGFKNELMVKDLELASGMALGIRSPIPLGAVAXQLYRIV 201
+ F + LM KDL LA+ A + P+PL Y V
Sbjct: 236 DEGFAPRFSSRLMSKDLRLATSAASNVGQPLPLTGKTVTFYEKV 279
>UniRef50_A0JUJ6 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=2;
Micrococcineae|Rep: 3-hydroxyisobutyrate dehydrogenase -
Arthrobacter sp. (strain FB24)
Length = 300
Score = 102 bits (244), Expect = 1e-20
Identities = 58/180 (32%), Positives = 92/180 (51%)
Frame = -3
Query: 689 GLGFTXAPVXGGVMGAQNVTXAFMAGGXKEDFERSLXLLKVMGXKQFHCGQIGSGQVAKL 510
G F APV GG+ GA+ T FM GG + ++ M G +GQ AK+
Sbjct: 113 GFRFVDAPVSGGMSGAKAGTLTFMIGGDAGAVAEATEYIRPMASNIIPTGGPTTGQAAKI 172
Query: 509 TNNMLMGITGMATAECMNMGIKMGLEPKVLLDVLNNSSARSWSTEVYCPVPGLVPTAPSS 330
NN+++ I +TAE + ++GL+ +V D+ + SS SW+ + PV G+VPTA S+
Sbjct: 173 CNNLMLFINLASTAEGAVLAERLGLDKQVFWDIASVSSGDSWALRTWYPVGGVVPTAASN 232
Query: 329 RNYDGGFKNELMVKDLELASGMALGIRSPIPLGAVAXQLYRIVQSRGYGQKDFSFVFQLL 150
++ F EL KD+ LA A +P+ +G L++ + G KD S + +L+
Sbjct: 233 NDFAPTFTTELANKDIGLAISAARDTGTPLEIGEHVQTLFQRLIDSGQSGKDCSMIIKLV 292
>UniRef50_A3H5R1 Cluster: 6-phosphogluconate dehydrogenase,
NAD-binding; n=1; Caldivirga maquilingensis IC-167|Rep:
6-phosphogluconate dehydrogenase, NAD-binding -
Caldivirga maquilingensis IC-167
Length = 295
Score = 101 bits (241), Expect = 3e-20
Identities = 65/186 (34%), Positives = 99/186 (53%), Gaps = 1/186 (0%)
Frame = -3
Query: 692 KGLGFTXAPVXGGVMGAQNVTXAFMAGGXKEDFERSLXLLKVMGXKQFHCGQIGSGQVAK 513
KG AP+ G + + + GG +E +ER+ ++K H G G G AK
Sbjct: 113 KGGLMVDAPIIGTSILIEKREAVVLIGGEREAYERAYEVVKHFARYVVHVGPNGYGLYAK 172
Query: 512 LTNNMLMGITGMATAECMNMGIKMGLEPKVLLDVLNN-SSARSWSTEVYCPVPGLVPTAP 336
L NN L+G A AE +N+G MGL V++DVL SSARS ++E+ VP ++
Sbjct: 173 LINNALLGSYVAALAEVVNLGEAMGLSSSVIMDVLTKLSSARSPTSEL--KVPKMI---- 226
Query: 335 SSRNYDGGFKNELMVKDLELASGMALGIRSPIPLGAVAXQLYRIVQSRGYGQKDFSFVFQ 156
+ ++ F + M KDL+L + A + P+P+ A+A QLYR+ ++ G DFS V +
Sbjct: 227 -NNDFTTQFATKHMRKDLDLVNKEASRLGVPVPMAALALQLYRMSEADGLSDDDFSAVIK 285
Query: 155 LLKEEN 138
+LK N
Sbjct: 286 ILKRRN 291
>UniRef50_Q9LNP0 Cluster: F1L3.35; n=8; Magnoliophyta|Rep: F1L3.35 -
Arabidopsis thaliana (Mouse-ear cress)
Length = 387
Score = 97.9 bits (233), Expect = 3e-19
Identities = 56/181 (30%), Positives = 93/181 (51%)
Frame = -3
Query: 689 GLGFTXAPVXGGVMGAQNVTXAFMAGGXKEDFERSLXLLKVMGXKQFHCGQIGSGQVAKL 510
G F APV G A++ F+ G K +E++ L +MG +F+ G++G+G KL
Sbjct: 207 GALFLEAPVSGSKKPAEDGQLIFLTAGDKPLYEKAAPFLDIMGKSKFYLGEVGNGAAMKL 266
Query: 509 TNNMLMGITGMATAECMNMGIKMGLEPKVLLDVLNNSSARSWSTEVYCPVPGLVPTAPSS 330
NM+MG + AE + + K+GL+P VL++V++ + + P+ L +
Sbjct: 267 VVNMIMGSMMASFAEGILLSQKVGLDPNVLVEVVSQGA-------INAPMYSLKGPSMIK 319
Query: 329 RNYDGGFKNELMVKDLELASGMALGIRSPIPLGAVAXQLYRIVQSRGYGQKDFSFVFQLL 150
Y F + KD+ LA G+A + P+ A A +LY++ +S G +DFS V + L
Sbjct: 320 SVYPTAFPLKHQQKDMRLALGLAESVSQSTPIAAAANELYKVAKSYGLSDEDFSAVIEAL 379
Query: 149 K 147
K
Sbjct: 380 K 380
>UniRef50_Q8ES28 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=13;
Bacillaceae|Rep: 3-hydroxyisobutyrate dehydrogenase -
Oceanobacillus iheyensis
Length = 299
Score = 97.1 bits (231), Expect = 5e-19
Identities = 57/184 (30%), Positives = 96/184 (52%), Gaps = 1/184 (0%)
Frame = -3
Query: 692 KGLGFTXAPVXGGVMGAQNVTXAFMAGGXKEDFERSLXLLKVMGXKQFHCG-QIGSGQVA 516
+ + F APV GGV+GA+N T M GG +E F++ +L V+G FH G QI G
Sbjct: 112 RSIPFLAAPVSGGVVGAENQTLTVMVGGKEETFQKVKDILNVIGGNVFHVGEQIDKGTTV 171
Query: 515 KLTNNMLMGITGMATAECMNMGIKMGLEPKVLLDVLNNSSARSWSTEVYCPVPGLVPTAP 336
KL NN+L+G +E + + + ++ L ++N S +S +Y T
Sbjct: 172 KLINNLLIGFYTAGVSEALQIANQKDIDLNDLFSMMNVSYGQS---RIY---ERNYKTFI 225
Query: 335 SSRNYDGGFKNELMVKDLELASGMALGIRSPIPLGAVAXQLYRIVQSRGYGQKDFSFVFQ 156
+++ GF +L+ KDLE A +A + +P+ LYR ++ +GYG +D + +++
Sbjct: 226 EPNDFNPGFALKLLRKDLEFAMEVADNNQLDLPISKSLLDLYRNLEHQGYGDQDMAVLYK 285
Query: 155 LLKE 144
LK+
Sbjct: 286 YLKD 289
>UniRef50_Q1GJB9 Cluster: 6-phosphogluconate dehydrogenase
NAD-binding; n=1; Silicibacter sp. TM1040|Rep:
6-phosphogluconate dehydrogenase NAD-binding -
Silicibacter sp. (strain TM1040)
Length = 304
Score = 96.7 bits (230), Expect = 7e-19
Identities = 61/173 (35%), Positives = 89/173 (51%)
Frame = -3
Query: 689 GLGFTXAPVXGGVMGAQNVTXAFMAGGXKEDFERSLXLLKVMGXKQFHCGQIGSGQVAKL 510
G GF APV GG GA + + M GG + E + L+ M K H G G+G VAKL
Sbjct: 120 GHGFLDAPVSGGPAGAASGQLSVMLGGETQWLEAARPALEAMAAKILHVGPSGAGNVAKL 179
Query: 509 TNNMLMGITGMATAECMNMGIKMGLEPKVLLDVLNNSSARSWSTEVYCPVPGLVPTAPSS 330
NNML+ + T E + +G G+ K +L+V+N+++ RS +EV+ P ++P
Sbjct: 180 VNNMLVANHMVTTLEALRLGEAAGVAAKEMLEVVNSATGRSAISEVHYP-NWVLP----- 233
Query: 329 RNYDGGFKNELMVKDLELASGMALGIRSPIPLGAVAXQLYRIVQSRGYGQKDF 171
R++D GF LM KDL LA +A + P+ +L+ QS DF
Sbjct: 234 RSFDSGFSAGLMRKDLRLARALAAEVSVATPMADRVAELWAETQSGLSDSDDF 286
>UniRef50_Q01QM2 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=1;
Solibacter usitatus Ellin6076|Rep: 3-hydroxyisobutyrate
dehydrogenase - Solibacter usitatus (strain Ellin6076)
Length = 298
Score = 96.7 bits (230), Expect = 7e-19
Identities = 63/184 (34%), Positives = 95/184 (51%), Gaps = 2/184 (1%)
Frame = -3
Query: 692 KGLGFTXAPVXGGVMGAQNVTXAFMAGGXKEDFERSLXLLKVMGXKQFHCGQIGSGQVAK 513
K + F APV G GA++ FM GG + F + LL MG K + CG G G AK
Sbjct: 113 KSVDFLDAPVTGSTPGAESGNLTFMIGGDEAVFSKIRPLLDPMGKKIYFCGGAGMGLQAK 172
Query: 512 LTNNMLMGITGMATAECMNMGIKMGLEPKVLLDVLNNSSARSWSTEVYCPVPGLVPTAPS 333
LT N+++ MA E M + K G++PK++L++L+NS+A+S P
Sbjct: 173 LTQNLVLSNILMAFNEGMVLATKGGMDPKLMLEILDNSAAKSGLISYKAPF-------VF 225
Query: 332 SRNYDGGFKNELMVKD--LELASGMALGIRSPIPLGAVAXQLYRIVQSRGYGQKDFSFVF 159
SRN+ F + M KD L L SG LG+ P+ L + QL++ + G+G +D
Sbjct: 226 SRNFTTNFSVKWMHKDIGLMLESGKDLGV--PLYLTGLTRQLFQTAIAAGHGDEDICSTI 283
Query: 158 QLLK 147
++L+
Sbjct: 284 KVLE 287
>UniRef50_A3LTC4 Cluster: 3-hydroxyisobutyrate dehydrogenase-like
protein; n=6; Saccharomycetales|Rep:
3-hydroxyisobutyrate dehydrogenase-like protein - Pichia
stipitis (Yeast)
Length = 355
Score = 96.3 bits (229), Expect = 9e-19
Identities = 62/189 (32%), Positives = 92/189 (48%), Gaps = 7/189 (3%)
Frame = -3
Query: 689 GLGFTXAPVXGGVMGAQNVTXAFMAGGXK-EDFERSLX-LLKVMGXKQFHCGQI-GSGQV 519
G F PV GGV GA+ T +FM E L LL MG F CG+ G+G
Sbjct: 153 GADFIDTPVSGGVAGARKATLSFMLSRPNNESISADLRTLLNKMGANIFACGETHGAGLA 212
Query: 518 AKLTNNMLMGITGMATAECMNMGIKMGLEPKVLLDVLNNSSARSWSTEVYCPVPGLVP-- 345
AKL+NN L+ +T +A A+ + GL K +++ S+ + W+ CP+PG P
Sbjct: 213 AKLSNNYLLAVTNLAVADSFQLAKSFGLNLKDYAKLVSVSTGKCWAAVDNCPIPGAYPKE 272
Query: 344 -TAPSSRNYDGGFKNELMVKDLELASGMALGIRSPIPLGAVAXQLY-RIVQSRGYGQKDF 171
P+ Y+GGF ++L KDL LA+ A + LG V+ Y + + +D
Sbjct: 273 NNLPADVKYEGGFISKLTRKDLVLATQSAEYANRFLYLGDVSKHWYDKACEREDLANRDL 332
Query: 170 SFVFQLLKE 144
S +++ L E
Sbjct: 333 SVLYEWLGE 341
>UniRef50_Q55W03 Cluster: Putative uncharacterized protein; n=2;
Filobasidiella neoformans|Rep: Putative uncharacterized
protein - Cryptococcus neoformans (Filobasidiella
neoformans)
Length = 414
Score = 95.1 bits (226), Expect = 2e-18
Identities = 59/181 (32%), Positives = 94/181 (51%), Gaps = 6/181 (3%)
Frame = -3
Query: 671 APVXGGVMGAQNVTXAFMAGGXKEDFER-SLXLLKVMGXKQ--FHCGQIGSGQVAKLTNN 501
APV GG + A+ M G R ++ LL++M + CG G+G K+ NN
Sbjct: 203 APVSGGTVAAERGELTIMFGSPAPIATRLAMPLLQMMAREGGVIECGGSGTGVGVKVCNN 262
Query: 500 MLMGITGMATAECMNMGIKMGLEPKVLLDVLNNSSARSWSTEVYCPVPGLVPTAPSSRNY 321
+++ +A +E + +G + ++ +L V+N SS SWS+ V P+ +P P+SR Y
Sbjct: 263 LVLASNQIALSEGLALGRSLNIDIALLQSVINTSSGSSWSSRVNPPISS-IPGTPASRGY 321
Query: 320 DGGFKNELMVKDLELASGMALGIRSPIPLGAVAXQLYRIVQSRGYG---QKDFSFVFQLL 150
GGF+ LM+KD+ LA A PL + + +Y + S G G KDFS+V +L
Sbjct: 322 SGGFQTRLMLKDVNLALQAANKHNLATPLTSASKSIYEAICSDGDGDWASKDFSWVKSML 381
Query: 149 K 147
+
Sbjct: 382 E 382
>UniRef50_Q1AVA4 Cluster: 2-hydroxy-3-oxopropionate reductase; n=6;
Bacteria|Rep: 2-hydroxy-3-oxopropionate reductase -
Rubrobacter xylanophilus (strain DSM 9941 / NBRC 16129)
Length = 309
Score = 94.3 bits (224), Expect = 4e-18
Identities = 58/183 (31%), Positives = 93/183 (50%)
Frame = -3
Query: 692 KGLGFTXAPVXGGVMGAQNVTXAFMAGGXKEDFERSLXLLKVMGXKQFHCGQIGSGQVAK 513
+G APV GG +GA+ T + M GG +EDF R+ L +VMG H G G+GQ+ K
Sbjct: 126 RGASMLDAPVSGGDVGAREGTLSIMVGGSEEDFGRARPLFEVMGKTVTHVGPSGAGQIVK 185
Query: 512 LTNNMLMGITGMATAECMNMGIKMGLEPKVLLDVLNNSSARSWSTEVYCPVPGLVPTAPS 333
N +++G+T A E + +G++ G+EP+ + +VL A + EV
Sbjct: 186 AANQIVVGLTIEAVCEALVLGLRGGVEPQKIFEVLCGGLAANRVMEV-------KREKFL 238
Query: 332 SRNYDGGFKNELMVKDLELASGMALGIRSPIPLGAVAXQLYRIVQSRGYGQKDFSFVFQL 153
SR++ G K KDL +A +P A+ QL+ ++++G G D S + L
Sbjct: 239 SRDFRPGGKARFHRKDLGIALNTGREYGVALPAAALVEQLFGALEAKGRGDLDHSALLLL 298
Query: 152 LKE 144
++E
Sbjct: 299 VEE 301
>UniRef50_Q13LQ9 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=11;
Proteobacteria|Rep: 3-hydroxyisobutyrate dehydrogenase -
Burkholderia xenovorans (strain LB400)
Length = 296
Score = 94.3 bits (224), Expect = 4e-18
Identities = 56/179 (31%), Positives = 87/179 (48%)
Frame = -3
Query: 686 LGFTXAPVXGGVMGAQNVTXAFMAGGXKEDFERSLXLLKVMGXKQFHCGQIGSGQVAKLT 507
L + APV GGV A+ T A + GG + R LL MG H G G+G AK
Sbjct: 119 LAYLDAPVSGGVKRAKEGTLAILVGGHADVLARCKPLLDAMGTNVLHIGTAGAGHAAKAL 178
Query: 506 NNMLMGITGMATAECMNMGIKMGLEPKVLLDVLNNSSARSWSTEVYCPVPGLVPTAPSSR 327
NN + + AT E + + + G++P+V+ DVLN S+ RS ++E S
Sbjct: 179 NNYVSAASVAATVEALQIASRFGIDPQVMTDVLNASTGRSNTSE------NKAKQFMLSG 232
Query: 326 NYDGGFKNELMVKDLELASGMALGIRSPIPLGAVAXQLYRIVQSRGYGQKDFSFVFQLL 150
+ GF +LM KDL++A +A + P+ GA +++ R D + +++LL
Sbjct: 233 TFASGFALQLMNKDLKIARALAQAVGHPMTFGATCVEVWDQAAQRSTPATDHTELYRLL 291
>UniRef50_Q9K9L1 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=2;
Bacillus|Rep: 3-hydroxyisobutyrate dehydrogenase -
Bacillus halodurans
Length = 299
Score = 93.9 bits (223), Expect = 5e-18
Identities = 65/185 (35%), Positives = 91/185 (49%), Gaps = 1/185 (0%)
Frame = -3
Query: 692 KGLGFTXAPVXGGVMGAQNVTXAFMAGGXKEDFERSLXLLKVMGXKQFHCGQIGSGQVAK 513
KG F APV GG MGA+ T M GG + FERS +L G H G IGSG V K
Sbjct: 113 KGGAFLDAPVSGGPMGAKAGTLTIMCGGEADSFERSKEVLGAYGDYIVHVGPIGSGTVVK 172
Query: 512 LTNNMLMGITGMATAECMNMGIKMGLEPKVLLDVLNNSSARSWSTEVYCPVPGLVPTAPS 333
L NNM++G+ EC K G++P + +++ S+ S S E V ++
Sbjct: 173 LANNMVIGVHQAVLGECYLFVEKAGVDPAIAYEIIKRSAGFSKSME--WSVDAIL----- 225
Query: 332 SRNYDGGFKNELMVKDLELASGMALGIRSPIPLGAVAXQLYRI-VQSRGYGQKDFSFVFQ 156
R +D F L+ KD+ LA + LG + IPL V R+ YG +D S + +
Sbjct: 226 DRAFDPRFSINLLHKDIGLA--LKLGEQLGIPLEMVEKGEERVRAAKEQYGHEDVSAIIR 283
Query: 155 LLKEE 141
L+E+
Sbjct: 284 PLEEK 288
>UniRef50_A2U9T6 Cluster: 6-phosphogluconate dehydrogenase,
NAD-binding; n=2; Bacillaceae|Rep: 6-phosphogluconate
dehydrogenase, NAD-binding - Bacillus coagulans 36D1
Length = 294
Score = 93.5 bits (222), Expect = 6e-18
Identities = 57/181 (31%), Positives = 91/181 (50%)
Frame = -3
Query: 680 FTXAPVXGGVMGAQNVTXAFMAGGXKEDFERSLXLLKVMGXKQFHCGQIGSGQVAKLTNN 501
F APV G V A+ +AGG KE+ + + +V+G H G+ G G AKL+ N
Sbjct: 120 FIDAPVSGSVQPAKEGNLVILAGGRKEEIDAVRPMFEVLGKTIIHFGENGKGSAAKLSIN 179
Query: 500 MLMGITGMATAECMNMGIKMGLEPKVLLDVLNNSSARSWSTEVYCPVPGLVPTAPSSRNY 321
+L+G+T +E + G K+GLE K L+++++ S+ + P+ + A ++
Sbjct: 180 LLLGLTIEGASEAILFGEKLGLEKKDLIEMISASACNT-------PIFQMKKKAFLQEDF 232
Query: 320 DGGFKNELMVKDLELASGMALGIRSPIPLGAVAXQLYRIVQSRGYGQKDFSFVFQLLKEE 141
F ELM KDL LA +PL A + Y ++ G G+ D + V+Q LK+
Sbjct: 233 PAAFMLELMAKDLGLAKEEIKKAGMSLPLADAAEKTYSRAKADGTGKADVAAVYQALKQL 292
Query: 140 N 138
N
Sbjct: 293 N 293
>UniRef50_Q0UVR9 Cluster: Putative uncharacterized protein; n=1;
Phaeosphaeria nodorum|Rep: Putative uncharacterized
protein - Phaeosphaeria nodorum (Septoria nodorum)
Length = 288
Score = 92.7 bits (220), Expect = 1e-17
Identities = 54/145 (37%), Positives = 81/145 (55%), Gaps = 6/145 (4%)
Frame = -3
Query: 692 KGLG-FTXAPVXGGVMGAQNVTXAFMAGGXKEDFERSLX-LLKVMGX--KQFHCGQIGSG 525
+GLG + APV GGV A+ T + + G D L L ++G K F+ +G+G
Sbjct: 78 EGLGTYIDAPVSGGVPAAEAGTLSMLIGAPPPDPTSLLPSTLSLLGTPSKFFYLHTLGAG 137
Query: 524 QVAKLTNNMLMGITGMATAECMNMGIKMGLEPKVLLDVLNNSSARSWSTEVYCPVPGLVP 345
AK++NN L G +ATAE + +G+K GL+P L V+ NS+ +SW + P+P +
Sbjct: 138 LTAKISNNYLSGTILLATAEALAIGVKHGLDPAALYSVIKNSTGQSWMCDHVLPIPNVQT 197
Query: 344 T--APSSRNYDGGFKNELMVKDLEL 276
PS+ Y GFK ++M+KDL L
Sbjct: 198 EYWVPSNSGYKPGFKTQMMLKDLGL 222
>UniRef50_Q606G9 Cluster: Oxidoreductase, Gfo/Idh/MocA family; n=6;
Proteobacteria|Rep: Oxidoreductase, Gfo/Idh/MocA family
- Methylococcus capsulatus
Length = 289
Score = 91.9 bits (218), Expect = 2e-17
Identities = 58/179 (32%), Positives = 85/179 (47%)
Frame = -3
Query: 689 GLGFTXAPVXGGVMGAQNVTXAFMAGGXKEDFERSLXLLKVMGXKQFHCGQIGSGQVAKL 510
G F APV GGV GA++ T A M GG E E+ +L MG + H G G+GQ K
Sbjct: 110 GGDFLDAPVSGGVEGARDGTLALMIGGRAETVEKVRPVLAAMGSRLMHMGDTGAGQATKA 169
Query: 509 TNNMLMGITGMATAECMNMGIKMGLEPKVLLDVLNNSSARSWSTEVYCPVPGLVPTAPSS 330
N ++ A E + G + L+ ++DV++ +A +W + G S
Sbjct: 170 VNQVMCAGINQAVTEALAFGQALDLDLDKVIDVVSGGAAGNW----FLDKRGKTMIRGS- 224
Query: 329 RNYDGGFKNELMVKDLELASGMALGIRSPIPLGAVAXQLYRIVQSRGYGQKDFSFVFQL 153
+ GFK L KDL + MA + P+PL + Y + +RGYG D S +F+L
Sbjct: 225 --FQPGFKLSLHHKDLNICLEMAERLGIPLPLSTRSRDDYAELMARGYGDDDISGLFRL 281
>UniRef50_Q656T5 Cluster: Oxidoreductase-like; n=3; Oryza
sativa|Rep: Oxidoreductase-like - Oryza sativa subsp.
japonica (Rice)
Length = 341
Score = 91.1 bits (216), Expect = 3e-17
Identities = 56/181 (30%), Positives = 88/181 (48%)
Frame = -3
Query: 689 GLGFTXAPVXGGVMGAQNVTXAFMAGGXKEDFERSLXLLKVMGXKQFHCGQIGSGQVAKL 510
G F APV G A++ F+ G + + R LL VMG +F G +G G KL
Sbjct: 162 GASFLEAPVSGSKKPAEDGLLIFLTAGDESLYNRVASLLDVMGKSRFFLGDVGKGADMKL 221
Query: 509 TNNMLMGITGMATAECMNMGIKMGLEPKVLLDVLNNSSARSWSTEVYCPVPGLVPTAPSS 330
NM+MG ++ +E + + K+GL+P L++V++ + + P+ L +
Sbjct: 222 VVNMVMGSMMVSFSEGLLLSEKVGLDPNTLVEVISQGA-------ISAPMFSLKGPSMVK 274
Query: 329 RNYDGGFKNELMVKDLELASGMALGIRSPIPLGAVAXQLYRIVQSRGYGQKDFSFVFQLL 150
Y F + KDL LA +A + IP A A +LY++ +S G +DFS V + L
Sbjct: 275 AAYPTAFPLKHQQKDLRLALALAESVSQSIPTVAAANELYKVAKSLGLADQDFSAVIEAL 334
Query: 149 K 147
K
Sbjct: 335 K 335
>UniRef50_Q8KL12 Cluster: Probable 6-phosphogluconate dehydrogenase
protein; n=1; Rhizobium etli CFN 42|Rep: Probable
6-phosphogluconate dehydrogenase protein - Rhizobium
etli (strain CFN 42 / ATCC 51251)
Length = 294
Score = 90.2 bits (214), Expect = 6e-17
Identities = 51/153 (33%), Positives = 81/153 (52%)
Frame = -3
Query: 695 RKGLGFTXAPVXGGVMGAQNVTXAFMAGGXKEDFERSLXLLKVMGXKQFHCGQIGSGQVA 516
+KGL APV GGV A + MAGG +D +++ +L MG + F G IGSG
Sbjct: 115 QKGLRLVDAPVSGGVKRAVEGSLTIMAGGASDDIDQADPILCAMGGQIFRTGPIGSGHAM 174
Query: 515 KLTNNMLMGITGMATAECMNMGIKMGLEPKVLLDVLNNSSARSWSTEVYCPVPGLVPTAP 336
K NN + G +A E + +G GL+P+ ++D+LN+SS ++ +TEV +
Sbjct: 175 KAINNFVSGAGVLAAIEGVLLGRTFGLDPRTIVDILNSSSGKNNATEV------KMKQFI 228
Query: 335 SSRNYDGGFKNELMVKDLELASGMALGIRSPIP 237
S + GF LM KD+ +A+ ++ + +P
Sbjct: 229 LSETFGSGFALGLMAKDIRIAADLSKALNLQLP 261
>UniRef50_P0ABQ3 Cluster: 2-hydroxy-3-oxopropionate reductase; n=25;
Bacteria|Rep: 2-hydroxy-3-oxopropionate reductase -
Escherichia coli O6
Length = 294
Score = 90.2 bits (214), Expect = 6e-17
Identities = 51/175 (29%), Positives = 86/175 (49%)
Frame = -3
Query: 692 KGLGFTXAPVXGGVMGAQNVTXAFMAGGXKEDFERSLXLLKVMGXKQFHCGQIGSGQVAK 513
KG+ APV GG A + T + M GG K F++ L+K M H G+IG+G V K
Sbjct: 111 KGIDMLDAPVSGGEPKAIDGTLSVMVGGDKAIFDKYYDLMKAMAGSVVHTGEIGAGNVTK 170
Query: 512 LTNNMLMGITGMATAECMNMGIKMGLEPKVLLDVLNNSSARSWSTEVYCPVPGLVPTAPS 333
L N +++ + A +E + + K G+ P ++ + A S + P+
Sbjct: 171 LANQVIVALNIAAMSEALTLATKAGVNPDLVYQAIRGGLAGSTVLDAKAPM-------VM 223
Query: 332 SRNYDGGFKNELMVKDLELASGMALGIRSPIPLGAVAXQLYRIVQSRGYGQKDFS 168
RN+ GF+ +L +KDL A + G+ + +PL A ++ + +++ G G D S
Sbjct: 224 DRNFKPGFRIDLHIKDLANALDTSHGVGAQLPLTAAVMEMMQALRADGLGTADHS 278
>UniRef50_Q8U2W2 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=17;
Pyrococcus|Rep: 3-hydroxyisobutyrate dehydrogenase -
Pyrococcus furiosus
Length = 278
Score = 89.8 bits (213), Expect = 8e-17
Identities = 53/182 (29%), Positives = 89/182 (48%)
Frame = -3
Query: 689 GLGFTXAPVXGGVMGAQNVTXAFMAGGXKEDFERSLXLLKVMGXKQFHCGQIGSGQVAKL 510
G + +PV G V+ A+N + G +E FER L+ +G + F+ + G KL
Sbjct: 103 GAFYLESPVIGSVIPARNGQLTILVSGEREAFERVRPYLQKLGKRIFYFNEPGKATKLKL 162
Query: 509 TNNMLMGITGMATAECMNMGIKMGLEPKVLLDVLNNSSARSWSTEVYCPVPGLVPTAPSS 330
NN ++G A E + +G K GL + ++++L N + S V T +
Sbjct: 163 INNFVLGAFMAALGEAIALGEKAGLSREEIIEILENGAGNSM-------VLSAKKTKLLN 215
Query: 329 RNYDGGFKNELMVKDLELASGMALGIRSPIPLGAVAXQLYRIVQSRGYGQKDFSFVFQLL 150
+Y F + +VKDL A +A+ R +PL A ++YR+ +G + DFS V++L
Sbjct: 216 DDYSTHFSVKNLVKDLSYAYDLAVASRKAVPLNATVREIYRLAFEKGLEELDFSVVYRLF 275
Query: 149 KE 144
+E
Sbjct: 276 RE 277
>UniRef50_A0FZ96 Cluster: 6-phosphogluconate dehydrogenase,
NAD-binding; n=1; Burkholderia phymatum STM815|Rep:
6-phosphogluconate dehydrogenase, NAD-binding -
Burkholderia phymatum STM815
Length = 305
Score = 89.4 bits (212), Expect = 1e-16
Identities = 53/163 (32%), Positives = 90/163 (55%), Gaps = 1/163 (0%)
Frame = -3
Query: 689 GLGFTXAPVXGGVMGAQNVTXAFMAGGXKEDFERSLXLLKVMGXKQFHCGQ-IGSGQVAK 513
G+ APV G + A T + +A G K+ FE++L +L+ + FHCG+ +G+GQ K
Sbjct: 111 GVALFDAPVSGAMATAIAGTISIIASGPKDAFEKTLPVLQSISPNVFHCGERVGNGQTMK 170
Query: 512 LTNNMLMGITGMATAECMNMGIKMGLEPKVLLDVLNNSSARSWSTEVYCPVPGLVPTAPS 333
NNM+ +AT E + MG K GL +++ + +N ++AR+++++ G++P
Sbjct: 171 TVNNMMNVSCRLATLEVVAMGRKFGLPLELMTEAINATTARNYTSQ------GMLPAIAE 224
Query: 332 SRNYDGGFKNELMVKDLELASGMALGIRSPIPLGAVAXQLYRI 204
R F L VKD+ A +A + P+P+GAVA + +I
Sbjct: 225 GRQ-STKFWLALQVKDIHQAITLAAEQKVPMPIGAVARSILQI 266
>UniRef50_Q0S5S3 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=1;
Rhodococcus sp. RHA1|Rep: 3-hydroxyisobutyrate
dehydrogenase - Rhodococcus sp. (strain RHA1)
Length = 299
Score = 88.6 bits (210), Expect = 2e-16
Identities = 58/182 (31%), Positives = 84/182 (46%)
Frame = -3
Query: 689 GLGFTXAPVXGGVMGAQNVTXAFMAGGXKEDFERSLXLLKVMGXKQFHCGQIGSGQVAKL 510
G F APV GGV GA+ T A M GG + ++ + L++ FH G GSGQ KL
Sbjct: 111 GACFLDAPVSGGVQGAEAGTLAVMLGGDEASVKKVIPLIETYAGNIFHVGPSGSGQAIKL 170
Query: 509 TNNMLMGITGMATAECMNMGIKMGLEPKVLLDVLNNSSARSWSTEVYCPVPGLVPTAPSS 330
NN + +A E ++ + G++ + VL SSA S Y P P+
Sbjct: 171 ANNQITAANIVALGEGLSSAVAAGVDLDTAVAVLTKSSANSNVLSNYFPKTLFTEERPT- 229
Query: 329 RNYDGGFKNELMVKDLELASGMALGIRSPIPLGAVAXQLYRIVQSRGYGQKDFSFVFQLL 150
GF + M KDL L A + P P+ ++ L+ I Q G G KDF+ V +
Sbjct: 230 -----GFALDFMHKDLGLFLNAAGKAKLPTPVTSLVRDLFSIGQRDGRGGKDFTSVVEFY 284
Query: 149 KE 144
++
Sbjct: 285 ED 286
>UniRef50_Q4WXG9 Cluster: 3-hydroxyisobutyrate dehydrogenase,
putative; n=1; Aspergillus fumigatus|Rep:
3-hydroxyisobutyrate dehydrogenase, putative -
Aspergillus fumigatus (Sartorya fumigata)
Length = 317
Score = 88.2 bits (209), Expect = 2e-16
Identities = 59/162 (36%), Positives = 81/162 (50%)
Frame = -3
Query: 692 KGLGFTXAPVXGGVMGAQNVTXAFMAGGXKEDFERSLXLLKVMGXKQFHCGQIGSGQVAK 513
K F APV GG +GA T FM G ++D L + F CG G AK
Sbjct: 136 KTAAFYDAPVSGGSLGAVAGTLTFMVGCVEDDPNLELLI--------FPCGGFLLGLTAK 187
Query: 512 LTNNMLMGITGMATAECMNMGIKMGLEPKVLLDVLNNSSARSWSTEVYCPVPGLVPTAPS 333
L NN G+ +ATAE MN+GIK G++P +L V S+A+S + + PVPG + P
Sbjct: 188 LCNNYCSGLIAIATAEAMNIGIKSGMKPSLLARVFATSTAQSTINDKWNPVPGCLSECPG 247
Query: 332 SRNYDGGFKNELMVKDLELASGMALGIRSPIPLGAVAXQLYR 207
+ +LM KDL LA A + + + LG A Q+Y+
Sbjct: 248 EQGV------QLMKKDLALAVEAADRVGAQLRLGVPALQVYQ 283
>UniRef50_A0JXR2 Cluster: 2-hydroxy-3-oxopropionate reductase; n=2;
Arthrobacter|Rep: 2-hydroxy-3-oxopropionate reductase -
Arthrobacter sp. (strain FB24)
Length = 333
Score = 87.8 bits (208), Expect = 3e-16
Identities = 52/174 (29%), Positives = 85/174 (48%)
Frame = -3
Query: 671 APVXGGVMGAQNVTXAFMAGGXKEDFERSLXLLKVMGXKQFHCGQIGSGQVAKLTNNMLM 492
APV GG GA++ T A M G ++DF+R L L MG G +GSG +AK N +++
Sbjct: 137 APVSGGTKGAEDGTLAIMVGAGEQDFQRLLPLFNAMGGTVRRLGPLGSGSLAKACNQLIV 196
Query: 491 GITGMATAECMNMGIKMGLEPKVLLDVLNNSSARSWSTEVYCPVPGLVPTAPSSRNYDGG 312
G T A AE + + G++ L ++L A S ++ P ++R+Y+
Sbjct: 197 GTTTAALAEAAELAERSGMDVAALYELLAGGLAGSRVLDIVGP-------RLAARDYEPT 249
Query: 311 FKNELMVKDLELASGMALGIRSPIPLGAVAXQLYRIVQSRGYGQKDFSFVFQLL 150
+ M KDL A + + +P+ V +LY ++ +G G D + V Q +
Sbjct: 250 GPAKFMHKDLSFVLESAAAVDAAVPMATVGAELYAELKRQGLGDLDLAAVRQTI 303
>UniRef50_A3RRS1 Cluster: 2-hydroxy-3-oxopropionate reductase; n=11;
Betaproteobacteria|Rep: 2-hydroxy-3-oxopropionate
reductase - Ralstonia solanacearum UW551
Length = 298
Score = 87.4 bits (207), Expect = 4e-16
Identities = 63/186 (33%), Positives = 91/186 (48%), Gaps = 2/186 (1%)
Frame = -3
Query: 689 GLGFTXAPVXGGVMGAQNVTXAFMAGGXKEDFERSLXLLKVMGXKQFHCGQIGSGQVAKL 510
GL F APV GG MGAQ T + M GG E ER LL+++G H G G+GQVAK
Sbjct: 117 GLDFLDAPVSGGTMGAQKATLSIMVGGKAEVLERVRPLLQLLGTTITHIGDHGAGQVAKA 176
Query: 509 TNNMLMGITGMATAECMNMGIKMGLEPKVLLDVLNNSSARSWSTEVYCPVPGLVPTAPSS 330
N ++ I AE M G +P +L + A S ++ P +
Sbjct: 177 CNQIVQVINIQGIAEAMLFARAQGTDPSRVLAAIGPGFAGSRMLDMMGP-------KMAE 229
Query: 329 RNYDGGFKNELMVKDLELASGMA--LGIRSPIPLGAVAXQLYRIVQSRGYGQKDFSFVFQ 156
R++ G + L KD L +A LG++ P + VA QL +V S G+G+ D S + +
Sbjct: 230 RDFAAGIEARLHDKDFGLVRDIARELGLKMP-AMELVASQLDALVAS-GWGRDDTSSLLR 287
Query: 155 LLKEEN 138
+L+ +N
Sbjct: 288 VLEAQN 293
>UniRef50_Q9HLR4 Cluster: Putative uncharacterized protein Ta0161;
n=2; Thermoplasma|Rep: Putative uncharacterized protein
Ta0161 - Thermoplasma acidophilum
Length = 290
Score = 87.4 bits (207), Expect = 4e-16
Identities = 54/183 (29%), Positives = 92/183 (50%), Gaps = 1/183 (0%)
Frame = -3
Query: 692 KGLGFTXAPVXGGVMGAQNVTXAFMAGGXKEDFERSLXLLKVMGXKQFHCGQIGSGQVAK 513
KG APV G + + + GG ++ L+ + + G GSG AK
Sbjct: 115 KGGKMYDAPVIGTSIAVEKKALVVLVGGDLSGYDEVRDLISATANQVVYMGDNGSGLYAK 174
Query: 512 LTNNMLMGITGMATAECMNMGIKMGLEPKVLLDVLNN-SSARSWSTEVYCPVPGLVPTAP 336
L NN+ +G + AE + G K G+ + DVL SSARS ++++ VP ++
Sbjct: 175 LVNNLFLGSYMASLAEAVRFGRKNGIPDSTISDVLTKYSSARSPTSDL--KVPKMI---- 228
Query: 335 SSRNYDGGFKNELMVKDLELASGMALGIRSPIPLGAVAXQLYRIVQSRGYGQKDFSFVFQ 156
S +Y F + M+KD+E+ MA R +P+ ++A QL+R + GYG++D + +++
Sbjct: 229 -SEDYSVQFSIKNMLKDMEIVDRMASEKRIALPVASLALQLFRYLMDSGYGEEDIAAIYR 287
Query: 155 LLK 147
L+
Sbjct: 288 ALR 290
>UniRef50_Q2BFK1 Cluster: Oxidoreductase; n=1; Bacillus sp. NRRL
B-14911|Rep: Oxidoreductase - Bacillus sp. NRRL B-14911
Length = 270
Score = 87.0 bits (206), Expect = 6e-16
Identities = 59/178 (33%), Positives = 86/178 (48%)
Frame = -3
Query: 695 RKGLGFTXAPVXGGVMGAQNVTXAFMAGGXKEDFERSLXLLKVMGXKQFHCGQIGSGQVA 516
+KG+ PV GG GA+N T MAGG + ER +L+ M + G +G G+
Sbjct: 96 QKGIPVLDGPVSGGTAGAENGTLTVMAGGDADVLERLRPVLESMATNIYLVGSVGDGKAI 155
Query: 515 KLTNNMLMGITGMATAECMNMGIKMGLEPKVLLDVLNNSSARSWSTEVYCPVPGLVPTAP 336
K N ML GI A AE + + K+ ++ L V+ +SS SW E + GL+
Sbjct: 156 KAINQMLAGIHMAAAAEAVALAEKLEIDMDKLKAVVGSSSGNSWMLE--NKMDGLI---- 209
Query: 335 SSRNYDGGFKNELMVKDLELASGMALGIRSPIPLGAVAXQLYRIVQSRGYGQKDFSFV 162
R++ GFK LM KD+++A G +PL L++ + G KDFS V
Sbjct: 210 -RRDFTPGFKLNLMKKDIQIAVNEGNG--KQLPLANYVLDLFK-QSEKDAGDKDFSAV 263
>UniRef50_Q13PY3 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=2;
Burkholderiales|Rep: 3-hydroxyisobutyrate dehydrogenase
- Burkholderia xenovorans (strain LB400)
Length = 302
Score = 87.0 bits (206), Expect = 6e-16
Identities = 56/176 (31%), Positives = 87/176 (49%), Gaps = 1/176 (0%)
Frame = -3
Query: 680 FTXAPVXGGVMGAQNVTXAFMAGGXKEDFERSLXLLKVMGXKQFHCGQ-IGSGQVAKLTN 504
F APV GG + A+ T MA G E FE L+V+G F+ G G GQ K+ N
Sbjct: 114 FLGAPVSGGTVAAEKGTLTVMAAGPMEAFETVEPWLRVIGKNIFYLGSGAGLGQTMKIIN 173
Query: 503 NMLMGITGMATAECMNMGIKMGLEPKVLLDVLNNSSARSWSTEVYCPVPGLVPTAPSSRN 324
N L + +A+ E + G+K GL+ ++LD+LN SS RS++T +P R+
Sbjct: 174 NTLCAVGMVASCEALVFGVKAGLDSAMMLDILNVSSGRSFAT------LEKIPQCILHRD 227
Query: 323 YDGGFKNELMVKDLELASGMALGIRSPIPLGAVAXQLYRIVQSRGYGQKDFSFVFQ 156
+ F EL+ KD++L A + P+ + A ++G G KD++ +
Sbjct: 228 FPMRFTTELIHKDVKLCIEEAEKLGVPMIVSPAARAFLSFAITQGDGGKDYAHTIE 283
>UniRef50_Q97XZ7 Cluster: Oxidoreductase; n=6; Thermoprotei|Rep:
Oxidoreductase - Sulfolobus solfataricus
Length = 289
Score = 87.0 bits (206), Expect = 6e-16
Identities = 52/170 (30%), Positives = 85/170 (50%)
Frame = -3
Query: 689 GLGFTXAPVXGGVMGAQNVTXAFMAGGXKEDFERSLXLLKVMGXKQFHCGQIGSGQVAKL 510
G+ F APV GG GA+ T M GG ++ F+R + K MG H G +GSGQ KL
Sbjct: 112 GMEFLDAPVTGGDKGAREGTLTIMVGGKEDVFKRVEPIFKAMGKNIIHVGDVGSGQALKL 171
Query: 509 TNNMLMGITGMATAECMNMGIKMGLEPKVLLDVLNNSSARSWSTEVYCPVPGLVPTAPSS 330
N +++ + ++ E + + +G++ L VL+ +A S++ + Y P
Sbjct: 172 CNQVVVALNMVSVVEGLLLARSLGIDDDKLFSVLSTGAANSFTVQYYLP-------KIMK 224
Query: 329 RNYDGGFKNELMVKDLELASGMALGIRSPIPLGAVAXQLYRIVQSRGYGQ 180
+ + GFK + KDL+ A +A P+ ++A QLY + S G G+
Sbjct: 225 GDLNPGFKAAHLKKDLKYAMEIANSKSLPLLGTSLALQLYNAMVSLGIGE 274
>UniRef50_Q0LNZ7 Cluster: 3-hydroxyisobutyrate dehydrogenase
precursor; n=1; Herpetosiphon aurantiacus ATCC
23779|Rep: 3-hydroxyisobutyrate dehydrogenase precursor
- Herpetosiphon aurantiacus ATCC 23779
Length = 301
Score = 86.6 bits (205), Expect = 7e-16
Identities = 56/172 (32%), Positives = 86/172 (50%)
Frame = -3
Query: 671 APVXGGVMGAQNVTXAFMAGGXKEDFERSLXLLKVMGXKQFHCGQIGSGQVAKLTNNMLM 492
APV GG A+ A M GG FER +L+V+G + G GSG V KL NN+ +
Sbjct: 122 APVSGGPARAKTGELAIMVGGEPSTFERCQAVLEVLGGAVSYIGASGSGSVVKLCNNLAI 181
Query: 491 GITGMATAECMNMGIKMGLEPKVLLDVLNNSSARSWSTEVYCPVPGLVPTAPSSRNYDGG 312
I MA E + G+ G+E + + +VL N++A ++ E + +P S +Y+ G
Sbjct: 182 SIIAMANIEALAFGVANGVEAETIRNVLLNATASNYLLERW------LPETVFSGDYNKG 235
Query: 311 FKNELMVKDLELASGMALGIRSPIPLGAVAXQLYRIVQSRGYGQKDFSFVFQ 156
F EL+ KDL A P+ G +A Q++ I Q + D++ + Q
Sbjct: 236 FAAELLAKDLNAVLDTARASGVPLWAGGLAQQMW-IAQKALDPRSDYTALAQ 286
>UniRef50_Q41DK0 Cluster: 6-phosphogluconate dehydrogenase,
NAD-binding; n=2; Bacillaceae|Rep: 6-phosphogluconate
dehydrogenase, NAD-binding - Exiguobacterium sibiricum
255-15
Length = 293
Score = 86.2 bits (204), Expect = 1e-15
Identities = 58/183 (31%), Positives = 88/183 (48%)
Frame = -3
Query: 689 GLGFTXAPVXGGVMGAQNVTXAFMAGGXKEDFERSLXLLKVMGXKQFHCGQIGSGQVAKL 510
GL APV GG +GA+N T A + GG + F+ L + MG G G GQ AKL
Sbjct: 114 GLHALDAPVTGGDLGAKNGTLAILVGGEEAAFDTVKPLFEAMGKSIARFGGPGQGQSAKL 173
Query: 509 TNNMLMGITGMATAECMNMGIKMGLEPKVLLDVLNNSSARSWSTEVYCPVPGLVPTAPSS 330
N + + + + TAE + K G++P + + + SA SWS E L+P +
Sbjct: 174 ANQIAIAGSMIGTAEMLLFVTKSGIDPTQFVATIKSGSAGSWSLE------NLIPRV-IA 226
Query: 329 RNYDGGFKNELMVKDLELASGMALGIRSPIPLGAVAXQLYRIVQSRGYGQKDFSFVFQLL 150
NY GF + +KD+ LA A + P A+ LY + + G+ + ++ LL
Sbjct: 227 ENYSPGFFVKHFIKDMRLALERADEMGISTPGLALVKDLYEELAASGHAESGTQALYLLL 286
Query: 149 KEE 141
KE+
Sbjct: 287 KEK 289
>UniRef50_Q3DYV4 Cluster: NADP oxidoreductase, coenzyme
F420-dependent:6-phosphogluconate dehydrogenase,
NAD-binding; n=2; Chloroflexus|Rep: NADP oxidoreductase,
coenzyme F420-dependent:6-phosphogluconate
dehydrogenase, NAD-binding - Chloroflexus aurantiacus
J-10-fl
Length = 289
Score = 86.2 bits (204), Expect = 1e-15
Identities = 57/183 (31%), Positives = 87/183 (47%)
Frame = -3
Query: 692 KGLGFTXAPVXGGVMGAQNVTXAFMAGGXKEDFERSLXLLKVMGXKQFHCGQIGSGQVAK 513
+G+G+ APV GG GA T A M GG D ER+ +L+ +G + H G G+G K
Sbjct: 105 RGIGWVDAPVSGGPEGAAAGTLAIMVGGTASDVERAEPILRALG-RPTHVGPPGAGHTVK 163
Query: 512 LTNNMLMGITGMATAECMNMGIKMGLEPKVLLDVLNNSSARSWSTEVYCPVPGLVPTAPS 333
+ N +++G+T A AE M + G++P +L L A S +++ +
Sbjct: 164 VINQLIVGLTIQAVAEAMVLAEAYGIDPALLRTALAGGFADSKVLQIH-------GQRMA 216
Query: 332 SRNYDGGFKNELMVKDLELASGMALGIRSPIPLGAVAXQLYRIVQSRGYGQKDFSFVFQL 153
+R Y G K +KDL +A+ MA +P Y + RG G+ D S + L
Sbjct: 217 ARRYTPGGKVTTQLKDLRMAAAMASAAGIALPHLNDTIARYETLVERGLGELDHSALHIL 276
Query: 152 LKE 144
L E
Sbjct: 277 LDE 279
>UniRef50_A0N0V2 Cluster: BtdhL; n=1; Azoarcus anaerobius|Rep: BtdhL
- Azoarcus anaerobius
Length = 303
Score = 86.2 bits (204), Expect = 1e-15
Identities = 54/183 (29%), Positives = 87/183 (47%)
Frame = -3
Query: 692 KGLGFTXAPVXGGVMGAQNVTXAFMAGGXKEDFERSLXLLKVMGXKQFHCGQIGSGQVAK 513
KG+ + APV G A +A G K+ +ER L LL+ MG K ++ G + K
Sbjct: 117 KGIHYLRAPVSGSTTTAAAGALTILASGPKDAYERCLPLLQAMGKKLYYLGPAEQARYLK 176
Query: 512 LTNNMLMGITGMATAECMNMGIKMGLEPKVLLDVLNNSSARSWSTEVYCPVPGLVPTAPS 333
+ NM++G+T E + +G + G+E +++V+NNS S P+ +
Sbjct: 177 VAINMMLGVTAGMLGEALALGERGGVEWAQMIEVINNSVVGS-------PLLAYKAEMLT 229
Query: 332 SRNYDGGFKNELMVKDLELASGMALGIRSPIPLGAVAXQLYRIVQSRGYGQKDFSFVFQL 153
+RN+ F M KD +LA P+PL AV+ Q + + G G+ DF +
Sbjct: 230 TRNFAPMFTASQMAKDFDLALEAGRDANVPMPLAAVSRQFLGAMIASGRGELDFFAYVTM 289
Query: 152 LKE 144
L+E
Sbjct: 290 LEE 292
>UniRef50_Q89UN2 Cluster: Bll1384 protein; n=9; Bacteria|Rep:
Bll1384 protein - Bradyrhizobium japonicum
Length = 356
Score = 85.8 bits (203), Expect = 1e-15
Identities = 56/176 (31%), Positives = 86/176 (48%)
Frame = -3
Query: 668 PVXGGVMGAQNVTXAFMAGGXKEDFERSLXLLKVMGXKQFHCGQIGSGQVAKLTNNMLMG 489
PV GGV GA+ T A M G K +FE L V+G F + G+ Q KL NN L
Sbjct: 172 PVSGGVGGAEKGTLAVMVSGPKAEFELLKPALDVIGKVFFIGEKPGAAQTMKLANNFLSA 231
Query: 488 ITGMATAECMNMGIKMGLEPKVLLDVLNNSSARSWSTEVYCPVPGLVPTAPSSRNYDGGF 309
+AT+E + MG+K GL+P V++DV+N S + ++ P + R +D GF
Sbjct: 232 TAIVATSEAVVMGVKAGLDPAVMIDVINAGSGMNTASR------DKFPRSVLPRTFDFGF 285
Query: 308 KNELMVKDLELASGMALGIRSPIPLGAVAXQLYRIVQSRGYGQKDFSFVFQLLKEE 141
LMVKD+ LA + + + +L+ V S DF+ + ++++
Sbjct: 286 ATGLMVKDVRLALEEMKQLGLSMEVADAVGRLWETVISAEGADSDFTAAIKPIEKK 341
>UniRef50_Q1QWU9 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=1;
Chromohalobacter salexigens DSM 3043|Rep:
3-hydroxyisobutyrate dehydrogenase - Chromohalobacter
salexigens (strain DSM 3043 / ATCC BAA-138 / NCIMB13768)
Length = 310
Score = 85.4 bits (202), Expect = 2e-15
Identities = 55/152 (36%), Positives = 72/152 (47%)
Frame = -3
Query: 689 GLGFTXAPVXGGVMGAQNVTXAFMAGGXKEDFERSLXLLKVMGXKQFHCGQIGSGQVAKL 510
GL + APV GG GA + + GG ER +L+ M + H G GSG V KL
Sbjct: 120 GLEWLDAPVSGGPAGAASGALGMLLGGESATIERLAPMLEAMSARHTHVGPAGSGHVVKL 179
Query: 509 TNNMLMGITGMATAECMNMGIKMGLEPKVLLDVLNNSSARSWSTEVYCPVPGLVPTAPSS 330
NN L + TAE + + + G++P L LN+ S RS +EV P L S
Sbjct: 180 ANNYLCAAHLLTTAEAVTLAARAGVDPAACLAGLNSGSGRSAVSEVNFPKWIL------S 233
Query: 329 RNYDGGFKNELMVKDLELASGMALGIRSPIPL 234
+D GF LM KDL LA A + P+ L
Sbjct: 234 DAFDSGFTTGLMRKDLRLARDAASNMGLPLEL 265
>UniRef50_A5V0D4 Cluster: 6-phosphogluconate dehydrogenase,
NAD-binding; n=4; Chloroflexaceae|Rep:
6-phosphogluconate dehydrogenase, NAD-binding -
Roseiflexus sp. RS-1
Length = 303
Score = 85.4 bits (202), Expect = 2e-15
Identities = 57/165 (34%), Positives = 83/165 (50%)
Frame = -3
Query: 671 APVXGGVMGAQNVTXAFMAGGXKEDFERSLXLLKVMGXKQFHCGQIGSGQVAKLTNNMLM 492
APV GG GA T + M GG FER+L + + MG H G IG+GQ KL N +L+
Sbjct: 122 APVSGGSEGAARGTLSIMVGGDVTQFERALPVFQAMGTTITHLGPIGAGQTTKLVNQILV 181
Query: 491 GITGMATAECMNMGIKMGLEPKVLLDVLNNSSARSWSTEVYCPVPGLVPTAPSSRNYDGG 312
+A +E + G++ + L+ ++ +A SW P LV R++ G
Sbjct: 182 VGHALAMSEALLFAQAGGVDLRKALEAVSGGAAGSWMLSNRGP-QILV------RDWRPG 234
Query: 311 FKNELMVKDLELASGMALGIRSPIPLGAVAXQLYRIVQSRGYGQK 177
F +L KDL L A + P+P A+ QLYR +Q+RG G +
Sbjct: 235 FTIDLQQKDLRLVLQEADRLGVPLPGTALIHQLYRTLQARGLGHE 279
>UniRef50_Q89HA0 Cluster: Oxidoreductase; n=1; Bradyrhizobium
japonicum|Rep: Oxidoreductase - Bradyrhizobium japonicum
Length = 313
Score = 85.0 bits (201), Expect = 2e-15
Identities = 55/183 (30%), Positives = 87/183 (47%)
Frame = -3
Query: 689 GLGFTXAPVXGGVMGAQNVTXAFMAGGXKEDFERSLXLLKVMGXKQFHCGQIGSGQVAKL 510
G G+ APV GG GA+ T A MAGG D ER + M + H G G+GQ AKL
Sbjct: 136 GAGWIDAPVSGGTKGAEEGTLAIMAGGDASDIERVRPYVLTMARRFTHMGPTGAGQTAKL 195
Query: 509 TNNMLMGITGMATAECMNMGIKMGLEPKVLLDVLNNSSARSWSTEVYCPVPGLVPTAPSS 330
N +++G AE + + G++ L + L A S +++ VP +V S
Sbjct: 196 CNQVIVGCAMAVLAEATRLAVNAGIDANRLPEALAGGFADSIPLQLF--VPRMVQGIHSP 253
Query: 329 RNYDGGFKNELMVKDLELASGMALGIRSPIPLGAVAXQLYRIVQSRGYGQKDFSFVFQLL 150
G M+KDL+ + +A +P+P+ +A QL+R+ ++ D +++L
Sbjct: 254 PL--GHIAT--MLKDLDTVADVAQTTSTPVPMATLAGQLFRLAKAARGADADALEIYKLS 309
Query: 149 KEE 141
E
Sbjct: 310 ATE 312
>UniRef50_Q18X68 Cluster: 6-phosphogluconate dehydrogenase,
NAD-binding; n=2; Desulfitobacterium hafniense|Rep:
6-phosphogluconate dehydrogenase, NAD-binding -
Desulfitobacterium hafniense (strain DCB-2)
Length = 298
Score = 85.0 bits (201), Expect = 2e-15
Identities = 52/172 (30%), Positives = 87/172 (50%)
Frame = -3
Query: 689 GLGFTXAPVXGGVMGAQNVTXAFMAGGXKEDFERSLXLLKVMGXKQFHCGQIGSGQVAKL 510
G+ F APV G A+ T M GG +E FE L+ K + GQ GSGQ+ KL
Sbjct: 111 GVEFIDAPVSGMESRAKEGTLTTMCGGKQELFENVKPYLQCFADKILYMGQPGSGQLTKL 170
Query: 509 TNNMLMGITGMATAECMNMGIKMGLEPKVLLDVLNNSSARSWSTEVYCPVPGLVPTAPSS 330
N +L I A AE + M +K+GL+P+ + V+N+ + RS+++E + P+
Sbjct: 171 INQLLFDINVAALAEILPMSVKLGLDPEKVGAVVNSGTGRSYASEFFIPM-------ILK 223
Query: 329 RNYDGGFKNELMVKDLELASGMALGIRSPIPLGAVAXQLYRIVQSRGYGQKD 174
++ G+ + KDL + ++ + P+P+ A Y++ +G G +D
Sbjct: 224 GSFMDGYPMKHAYKDLVSGAEISASLCIPMPVLGAATTTYQMALLKGLGDRD 275
>UniRef50_Q58PL4 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=1;
uncultured proteobacterium DelRiverFos06H03|Rep:
3-hydroxyisobutyrate dehydrogenase - uncultured
proteobacterium DelRiverFos06H03
Length = 299
Score = 84.2 bits (199), Expect = 4e-15
Identities = 57/184 (30%), Positives = 90/184 (48%), Gaps = 1/184 (0%)
Frame = -3
Query: 692 KGLGFTXAPVXGGVMGAQNVTXAFMAGGXKEDFERSLXLLKVMGXKQFHCGQIGSGQVAK 513
KG+ F APV V A + GG K+ FE+ + V+G K FH G+ G+G K
Sbjct: 116 KGVDFLEAPVTNAVDMAALGRLSIFVGGDKDCFEKHKPIFDVIGEKIFHVGEPGNGATIK 175
Query: 512 LTNNMLMGITGMATAECMNMGIKMGLEPKVLLDVLNNSSARSWSTEVYCPVPGLVPTAPS 333
L N+L ++ A E + +G K G+ + + + +S+ SW E VP +
Sbjct: 176 LLTNLLWFVSAAAIGEGLMLGAKAGIPLHTVWEAIKSSAGNSWVAE--HDVPSIF----- 228
Query: 332 SRNYDGGFKNELMVKDLELASGMALGIRSPIPLGAVAXQLYRIVQSRGYGQKDFSF-VFQ 156
+ +YD F L KDL L +G+A +P+G +A QL++ + YG + V +
Sbjct: 229 AGHYDPSFSLALCCKDLGLINGIAKSQGYDLPMGGMAQQLFQQAMAT-YGPEAAELHVVK 287
Query: 155 LLKE 144
LL+E
Sbjct: 288 LLEE 291
>UniRef50_Q01ZG6 Cluster: 2-hydroxy-3-oxopropionate reductase; n=6;
Bacteria|Rep: 2-hydroxy-3-oxopropionate reductase -
Solibacter usitatus (strain Ellin6076)
Length = 298
Score = 84.2 bits (199), Expect = 4e-15
Identities = 56/182 (30%), Positives = 87/182 (47%)
Frame = -3
Query: 692 KGLGFTXAPVXGGVMGAQNVTXAFMAGGXKEDFERSLXLLKVMGXKQFHCGQIGSGQVAK 513
KG+ F APV GG A + T A M GG E FER +L MG G +G+G V K
Sbjct: 112 KGVEFLDAPVSGGEPKAIDGTLAIMVGGKPEVFERVQPVLAKMGASVTLTGAVGAGNVTK 171
Query: 512 LTNNMLMGITGMATAECMNMGIKMGLEPKVLLDVLNNSSARSWSTEVYCPVPGLVPTAPS 333
L N +++ A E + + K GL+P+V+ + + A ST + P ++
Sbjct: 172 LANQIMVACNIAAMGEALVLATKAGLDPEVVFNAVKGGLA--GSTVLNAKAPMVI----- 224
Query: 332 SRNYDGGFKNELMVKDLELASGMALGIRSPIPLGAVAXQLYRIVQSRGYGQKDFSFVFQL 153
RN+ GF+ L KDL A A ++ +P ++A Q+ + + G G D S +
Sbjct: 225 GRNFKPGFRINLHEKDLRNALQAAESMKVSLPFTSLAQQMLIALMNDGKGNLDHSAIVNF 284
Query: 152 LK 147
++
Sbjct: 285 IE 286
>UniRef50_A0LDJ3 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=1;
Magnetococcus sp. MC-1|Rep: 3-hydroxyisobutyrate
dehydrogenase - Magnetococcus sp. (strain MC-1)
Length = 292
Score = 83.8 bits (198), Expect = 5e-15
Identities = 56/182 (30%), Positives = 83/182 (45%)
Frame = -3
Query: 689 GLGFTXAPVXGGVMGAQNVTXAFMAGGXKEDFERSLXLLKVMGXKQFHCGQIGSGQVAKL 510
G F APV G + AQ F+AGG +R LL MG CG +G G KL
Sbjct: 113 GGAFLDAPVSGSKIPAQTGKLVFLAGGHHAVIQRCEPLLLSMGSAVIPCGAVGDGTRMKL 172
Query: 509 TNNMLMGITGMATAECMNMGIKMGLEPKVLLDVLNNSSARSWSTEVYCPVPGLVPTAPSS 330
N+LM A AE + + GLE ++ +D + NS ++ P+ G+ A +
Sbjct: 173 AMNLLMSGMVQALAESLLLVRNSGLEDQLFMDAIKNS-------VLFAPILGMKGQAFLN 225
Query: 329 RNYDGGFKNELMVKDLELASGMALGIRSPIPLGAVAXQLYRIVQSRGYGQKDFSFVFQLL 150
R+++ F L+ KDL L AL +P G Q Y +G G D + + Q+L
Sbjct: 226 RDFEPHFPLHLLYKDLNLIHAQALEHHVALPAGDAIRQGYAQAMQQGLGGLDIAAILQVL 285
Query: 149 KE 144
++
Sbjct: 286 EK 287
>UniRef50_A0GI22 Cluster: 6-phosphogluconate dehydrogenase,
NAD-binding; n=1; Burkholderia phytofirmans PsJN|Rep:
6-phosphogluconate dehydrogenase, NAD-binding -
Burkholderia phytofirmans PsJN
Length = 355
Score = 83.8 bits (198), Expect = 5e-15
Identities = 56/180 (31%), Positives = 84/180 (46%)
Frame = -3
Query: 686 LGFTXAPVXGGVMGAQNVTXAFMAGGXKEDFERSLXLLKVMGXKQFHCGQIGSGQVAKLT 507
+G+ APV GGV GA T A MAGG D E LL + H G +G+GQ AKL
Sbjct: 175 IGWIDAPVSGGVAGATAGTLAVMAGGAAADVEAVKPLLGAYASRVTHMGDVGAGQTAKLC 234
Query: 506 NNMLMGITGMATAECMNMGIKMGLEPKVLLDVLNNSSARSWSTEVYCPVPGLVPTAPSSR 327
N ++ T A AE +++ + GL+ L + L A S + + P AP
Sbjct: 235 NQTIVTATLAAIAEAVSLAQRSGLDASRLTEGLAGGWADSVLLQTFVPRMTQTGLAPI-- 292
Query: 326 NYDGGFKNELMVKDLELASGMALGIRSPIPLGAVAXQLYRIVQSRGYGQKDFSFVFQLLK 147
G F+ KD++ + A +P+P+ + QL R+ + G G+ D S +L+
Sbjct: 293 ---GAFRT--FQKDIDTVAATAYETGTPMPVSSTVQQLLRLGAAMGLGEADLSAFIDVLQ 347
>UniRef50_Q97ZE5 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=4;
Sulfolobaceae|Rep: 3-hydroxyisobutyrate dehydrogenase -
Sulfolobus solfataricus
Length = 289
Score = 83.8 bits (198), Expect = 5e-15
Identities = 54/177 (30%), Positives = 90/177 (50%), Gaps = 1/177 (0%)
Frame = -3
Query: 671 APVXGGVMGAQNVTXAFMAGGXKEDFERSLXLLKVMGXKQFHCGQIGSGQVAKLTNNMLM 492
APV G + + + GG K+ F+ + K + G G G +KL NN+L+
Sbjct: 115 APVIGTSVFVEQKKLVVLVGGPKDKFDIVNDIAKETASLVVYMGPNGMGLYSKLVNNLLL 174
Query: 491 GITGMATAECMNMGIKMGLEPKVLLDVLNN-SSARSWSTEVYCPVPGLVPTAPSSRNYDG 315
A AE N GI+ GLEP+ ++++L SSARS +TE+ P L+ +Y
Sbjct: 175 ASYVAAIAEAYNFGIRAGLEPQQVVNILTTLSSARSPTTEL--KAPKLL-----KEDYST 227
Query: 314 GFKNELMVKDLELASGMALGIRSPIPLGAVAXQLYRIVQSRGYGQKDFSFVFQLLKE 144
F + M KDLE+ A ++ P+ ++ +LY++ ++ GY + DF V ++ K+
Sbjct: 228 QFATKHMRKDLEIIMREAQNLKIITPVSSLVLELYKMAEALGYSEADFISVVEVFKK 284
>UniRef50_O34948 Cluster: Uncharacterized oxidoreductase ykwC; n=19;
cellular organisms|Rep: Uncharacterized oxidoreductase
ykwC - Bacillus subtilis
Length = 288
Score = 83.8 bits (198), Expect = 5e-15
Identities = 57/180 (31%), Positives = 87/180 (48%)
Frame = -3
Query: 692 KGLGFTXAPVXGGVMGAQNVTXAFMAGGXKEDFERSLXLLKVMGXKQFHCGQIGSGQVAK 513
K L APV GG +GAQN T A M GG KE FE + + +MG + G GSGQ K
Sbjct: 113 KALFALDAPVSGGDIGAQNGTLAIMVGGEKEAFEACMPIFSLMGENIQYQGPAGSGQHTK 172
Query: 512 LTNNMLMGITGMATAECMNMGIKMGLEPKVLLDVLNNSSARSWSTEVYCPVPGLVPTAPS 333
+ N + + + AE M K GLEP+ +L + +A SWS + L P
Sbjct: 173 MCNQIAIAAGMIGVAEAMAYAQKSGLEPENVLKSITTGAAGSWS------LSNLAPRMLQ 226
Query: 332 SRNYDGGFKNELMVKDLELASGMALGIRSPIPLGAVAXQLYRIVQSRGYGQKDFSFVFQL 153
N++ GF + +KD+ +A A + +P ++A LY + ++G +++L
Sbjct: 227 G-NFEPGFYVKHFIKDMGIALEEAELMGEEMPGLSLAKSLYDKLAAQGEENSGTQSIYKL 285
>UniRef50_Q4KH51 Cluster: 3-hydroxyisobutyrate dehydrogenase family
protein; n=16; Gammaproteobacteria|Rep:
3-hydroxyisobutyrate dehydrogenase family protein -
Pseudomonas fluorescens (strain Pf-5 / ATCC BAA-477)
Length = 298
Score = 83.4 bits (197), Expect = 7e-15
Identities = 52/183 (28%), Positives = 90/183 (49%)
Frame = -3
Query: 692 KGLGFTXAPVXGGVMGAQNVTXAFMAGGXKEDFERSLXLLKVMGXKQFHCGQIGSGQVAK 513
+G+ + APV GG GA+ + A M GG D ER +L +G + H G +G+GQV K
Sbjct: 117 RGVAWVDAPVSGGTPGAEAGSLAIMVGGEATDVERVRPVLLTLGQRVTHMGAVGAGQVTK 176
Query: 512 LTNNMLMGITGMATAECMNMGIKMGLEPKVLLDVLNNSSARSWSTEVYCPVPGLVPTAPS 333
N M++ + AE + + + G++ +++ + L A S P+ L P
Sbjct: 177 ACNQMIVACNALVIAEVVALAERSGVDARLIAEALAGGFADS------KPLQILAPQMAE 230
Query: 332 SRNYDGGFKNELMVKDLELASGMALGIRSPIPLGAVAXQLYRIVQSRGYGQKDFSFVFQL 153
SR + ++KDL+ A + S P+ +A QL R+ +GY +KD + + +L
Sbjct: 231 SRFEPVKWHVRTLLKDLDGAVKFSREQGSATPISGLAAQLMRLHGGQGYLEKDPATLVRL 290
Query: 152 LKE 144
++
Sbjct: 291 YRD 293
>UniRef50_Q84VC8 Cluster: Gamma hydroxybutyrate dehydrogenase-like
protein; n=3; Magnoliophyta|Rep: Gamma hydroxybutyrate
dehydrogenase-like protein - Oryza sativa subsp.
japonica (Rice)
Length = 293
Score = 83.4 bits (197), Expect = 7e-15
Identities = 57/185 (30%), Positives = 94/185 (50%), Gaps = 2/185 (1%)
Frame = -3
Query: 695 RKGLGFTXAPVXGGVMGAQNVTXAFMAGGXKEDFERSLXLLKVMGXKQFHCGQIGSGQVA 516
+KG F APV G A++ +A G K ++ + V+G K F G+IG+G
Sbjct: 110 QKGGAFVEAPVSGSKKPAEDGQLVILAAGDKVLYDDMVPAFDVLGKKSFFLGEIGNGAKM 169
Query: 515 KLTNNMLMGITGMATAECMNMGIKMGLEPKVLLDVLNNSSARSWSTEVYCPVPGLVPTAP 336
KL NM+MG A +E +++ GL P+ LLDVL+ + + P+ L +
Sbjct: 170 KLVVNMIMGSMMNALSEGLSLADNSGLSPQTLLDVLDLGAIAN-------PMFKLKGPSM 222
Query: 335 SSRNYDGGFKNELMVKDLELASGMALGIRSPI--PLGAVAXQLYRIVQSRGYGQKDFSFV 162
+Y+ F + KD+ LA +ALG + + P+ A + + ++ +S G G DFS V
Sbjct: 223 LQGSYNPAFPLKHQQKDMRLA--LALGDENAVSMPVAAASNEAFKKARSLGLGDLDFSAV 280
Query: 161 FQLLK 147
+++LK
Sbjct: 281 YEVLK 285
>UniRef50_Q4FMJ3 Cluster: 6-phosphogluconate dehydrogenase; n=2;
Candidatus Pelagibacter ubique|Rep: 6-phosphogluconate
dehydrogenase - Pelagibacter ubique
Length = 289
Score = 83.0 bits (196), Expect = 9e-15
Identities = 46/185 (24%), Positives = 92/185 (49%)
Frame = -3
Query: 692 KGLGFTXAPVXGGVMGAQNVTXAFMAGGXKEDFERSLXLLKVMGXKQFHCGQIGSGQVAK 513
K + + APV GG +GA+ + A M GG +E F++ LLK++G G + SGQ++K
Sbjct: 111 KNINYLDAPVSGGTIGAEEASLAIMVGGDEETFKQCYDLLKILGNPTL-VGPVTSGQISK 169
Query: 512 LTNNMLMGITGMATAECMNMGIKMGLEPKVLLDVLNNSSARSWSTEVYCPVPGLVPTAPS 333
L N +++G+T A AE + + K G P +++ L+ W+ G
Sbjct: 170 LANQIIVGVTIGAVAEAVTLCEKSGTNPNKMIEALSG----GWADSKILQTHG---KRMI 222
Query: 332 SRNYDGGFKNELMVKDLELASGMALGIRSPIPLGAVAXQLYRIVQSRGYGQKDFSFVFQL 153
++++ K +KD+ + +P+ ++ ++Y+ + + G G D S +++
Sbjct: 223 NKDFTPKGKTTTQLKDMTNIINAGKAAETHLPISSLVKEMYKDLVADGQGNTDHSSLYKA 282
Query: 152 LKEEN 138
+++ N
Sbjct: 283 IEKIN 287
>UniRef50_Q11FC5 Cluster: 6-phosphogluconate dehydrogenase,
NAD-binding; n=2; Rhizobiales|Rep: 6-phosphogluconate
dehydrogenase, NAD-binding - Mesorhizobium sp. (strain
BNC1)
Length = 292
Score = 83.0 bits (196), Expect = 9e-15
Identities = 55/179 (30%), Positives = 85/179 (47%)
Frame = -3
Query: 692 KGLGFTXAPVXGGVMGAQNVTXAFMAGGXKEDFERSLXLLKVMGXKQFHCGQIGSGQVAK 513
+G+ APV GGV GA + M GG E F ++ +L+ MG H G +G GQV K
Sbjct: 112 RGVDLVDAPVSGGVRGAIAGELSIMCGGSPEAFAKARPVLEGMGTTIIHAGDLGMGQVFK 171
Query: 512 LTNNMLMGITGMATAECMNMGIKMGLEPKVLLDVLNNSSARSWSTEVYCPVPGLVPTAPS 333
+ N +++G+ A E + G + +L + L +A SW E L P
Sbjct: 172 MCNQLMVGVHIQAMCEAFALCRAQGGDLNLLRETLMGGAAGSWMLE------NLGPQV-I 224
Query: 332 SRNYDGGFKNELMVKDLELASGMALGIRSPIPLGAVAXQLYRIVQSRGYGQKDFSFVFQ 156
+++ GF+ +L +KDL LA A P+P A+A LY ++ G G +F+
Sbjct: 225 AKDDSAGFRIDLQLKDLRLAGEAAFEKGLPLPGLAMATSLYLEARAHGEGSNGNQAMFR 283
>UniRef50_A0UF54 Cluster: 6-phosphogluconate dehydrogenase,
NAD-binding; n=1; Burkholderia multivorans ATCC
17616|Rep: 6-phosphogluconate dehydrogenase, NAD-binding
- Burkholderia multivorans ATCC 17616
Length = 289
Score = 83.0 bits (196), Expect = 9e-15
Identities = 51/180 (28%), Positives = 82/180 (45%)
Frame = -3
Query: 689 GLGFTXAPVXGGVMGAQNVTXAFMAGGXKEDFERSLXLLKVMGXKQFHCGQIGSGQVAKL 510
G+GF PV GG GA T + GG E +L + KQ H G G+G V KL
Sbjct: 113 GIGFIDGPVSGGPKGAATATMTMVLGGADEHIAAVQPVLSAISAKQVHVGPAGAGHVTKL 172
Query: 509 TNNMLMGITGMATAECMNMGIKMGLEPKVLLDVLNNSSARSWSTEVYCPVPGLVPTAPSS 330
NN+L G+ + T+E + G++ L++ L+ S R+ +T PT +
Sbjct: 173 LNNLLTGVHLLVTSEAVRAAEAAGVDKARLIEALSGGSGRNSATLTN------YPTWILN 226
Query: 329 RNYDGGFKNELMVKDLELASGMALGIRSPIPLGAVAXQLYRIVQSRGYGQKDFSFVFQLL 150
+D GF +LM KD+ LA + P+ + A +L+ +DF+ + + +
Sbjct: 227 ERFDSGFTMKLMRKDMRLALELLQRAHVSAPIASEAGRLWAASAESIGDAEDFNRIVEFV 286
>UniRef50_Q4Q7T9 Cluster: 2-hydroxy-3-oxopropionate reductase,
putative; n=6; Trypanosomatidae|Rep:
2-hydroxy-3-oxopropionate reductase, putative -
Leishmania major
Length = 299
Score = 83.0 bits (196), Expect = 9e-15
Identities = 53/175 (30%), Positives = 82/175 (46%)
Frame = -3
Query: 671 APVXGGVMGAQNVTXAFMAGGXKEDFERSLXLLKVMGXKQFHCGQIGSGQVAKLTNNMLM 492
APV GG +GA+N T M GG L +L +G K H G G+GQV K N +++
Sbjct: 119 APVSGGDIGARNGTLTVMVGGDAAALATVLPVLLAVGKKVTHIGDCGAGQVCKAANQIMV 178
Query: 491 GITGMATAECMNMGIKMGLEPKVLLDVLNNSSARSWSTEVYCPVPGLVPTAPSSRNYDGG 312
+A E + K G+ +++ + + SA+ W+ +V P + N G
Sbjct: 179 AAQMVALGEILVFCEKCGVSGPTVIEAIKSGSAQCWTLDV-------KPDRLFAGNRAPG 231
Query: 311 FKNELMVKDLELASGMALGIRSPIPLGAVAXQLYRIVQSRGYGQKDFSFVFQLLK 147
FK L KD+ + A P+P AV QL++ + G G +D S V +L+
Sbjct: 232 FKAALQSKDMGIVMDTAKEFGVPLPSTAVNTQLFQAMVQNGDGDRDNSAVVSVLE 286
>UniRef50_Q7WG50 Cluster: Probable oxidoreductase; n=1; Bordetella
bronchiseptica|Rep: Probable oxidoreductase - Bordetella
bronchiseptica (Alcaligenes bronchisepticus)
Length = 316
Score = 82.6 bits (195), Expect = 1e-14
Identities = 52/183 (28%), Positives = 89/183 (48%), Gaps = 1/183 (0%)
Frame = -3
Query: 692 KGLGFTXAPVXGGVMGAQNVTXAFMAGGXKEDFERSLXLLKVMGXKQFHCGQIGSGQVAK 513
+G+ +PV M AQ T +A G +D R+ L MG + CG++G G K
Sbjct: 114 RGMRMLDSPVGRSAMEAQRGTLLILASGSAQDKARARDALLCMGNQVIDCGEVGGGSRVK 173
Query: 512 LTNNMLMGIT-GMATAECMNMGIKMGLEPKVLLDVLNNSSARSWSTEVYCPVPGLVPTAP 336
+ NN MGI+ TAE + + GL ++ L+V+ + A + P
Sbjct: 174 VVNN-FMGISLNALTAEALTLAEASGLSVELALEVMRGTIAGLGHMNI------TYPNKV 226
Query: 335 SSRNYDGGFKNELMVKDLELASGMALGIRSPIPLGAVAXQLYRIVQSRGYGQKDFSFVFQ 156
+ GF+ +L KDL LA +A R+ +P+G+ A Q Y +++G G +D+S ++
Sbjct: 227 LRGDLSAGFQVDLAHKDLGLALELAARSRACVPMGSAAFQSYTAARAQGRGGQDYSAIYP 286
Query: 155 LLK 147
+++
Sbjct: 287 VMR 289
>UniRef50_A6SW62 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=1;
Janthinobacterium sp. Marseille|Rep:
3-hydroxyisobutyrate dehydrogenase - Janthinobacterium
sp. (strain Marseille) (Minibacterium massiliensis)
Length = 298
Score = 82.6 bits (195), Expect = 1e-14
Identities = 50/174 (28%), Positives = 82/174 (47%)
Frame = -3
Query: 689 GLGFTXAPVXGGVMGAQNVTXAFMAGGXKEDFERSLXLLKVMGXKQFHCGQIGSGQVAKL 510
G+G+ APV GGV+ A++ + M G ER L MG K + CG IGS V K
Sbjct: 116 GIGYLDAPVMGGVVFAKDASLDIMVSGDDASIERCRPLFDAMGRKLWPCGDIGSAHVLKA 175
Query: 509 TNNMLMGITGMATAECMNMGIKMGLEPKVLLDVLNNSSARSWSTEVYCPVPGLVPTAPSS 330
N + + T E M +G K GL+ KV+ + ++ V +P ++ +
Sbjct: 176 MTNYINACALINTLEAMTIGRKFGLDSKVMAEAIDVMCNGRQHPVVKKIIPHVL-----T 230
Query: 329 RNYDGGFKNELMVKDLELASGMALGIRSPIPLGAVAXQLYRIVQSRGYGQKDFS 168
+ G +L+ KD+++A A + + +PLG +L+R + G +D S
Sbjct: 231 HKFGTGMAMQLIAKDVKIAVDSAHSVGAAVPLGEATEKLWRAACEQIGGSRDHS 284
>UniRef50_A5P0V0 Cluster: 6-phosphogluconate dehydrogenase,
NAD-binding precursor; n=3; Rhizobiales|Rep:
6-phosphogluconate dehydrogenase, NAD-binding precursor
- Methylobacterium sp. 4-46
Length = 299
Score = 82.6 bits (195), Expect = 1e-14
Identities = 56/177 (31%), Positives = 88/177 (49%), Gaps = 1/177 (0%)
Frame = -3
Query: 689 GLGFTXAPVXGGVMGAQNVTXAFMAGGXKEDFERSLXLLKVMGXKQFHCG-QIGSGQVAK 513
G F APV GGV+GA+ + MA E F LL +G + FH G + G G K
Sbjct: 119 GRRFVDAPVSGGVVGAEAGSLTVMAAAPAEVFGAVRPLLDAVGARIFHVGTRPGQGATVK 178
Query: 512 LTNNMLMGITGMATAECMNMGIKMGLEPKVLLDVLNNSSARSWSTEVYCPVPGLVPTAPS 333
N +L G+ A AE +++ ++G++ V+L++L+ SSA SW + P ++ AP
Sbjct: 179 AVNQLLCGVHIAAAAEALSLAERVGVDLPVVLEILSGSSAASWM--LRDRGPRMLEEAPR 236
Query: 332 SRNYDGGFKNELMVKDLELASGMALGIRSPIPLGAVAXQLYRIVQSRGYGQKDFSFV 162
+ ++ VKDL + ++ +PL ++A QL+ RG G D S V
Sbjct: 237 VTS-----AVDIFVKDLGIVLEAGRDQKAALPLASLAHQLFLAASGRGEGAADDSQV 288
>UniRef50_Q0QWD5 Cluster: Putative 3-hydroxyisobutyrate
dehydrogenase; n=1; Leptosphaeria maculans|Rep: Putative
3-hydroxyisobutyrate dehydrogenase - Leptosphaeria
maculans (Blackleg fungus)
Length = 296
Score = 82.6 bits (195), Expect = 1e-14
Identities = 48/137 (35%), Positives = 75/137 (54%), Gaps = 5/137 (3%)
Frame = -3
Query: 554 QFH-CGQIGSGQVAKLTNNMLMGITGMATAECMNMGIKMGLEPKVLLDVLNNSSARSWST 378
+FH +G+G AK+ NN L G +ATAE + +G + GL+P+ L V+ +S+ +SW
Sbjct: 135 KFHYLSTLGAGLTAKIANNYLSGTILLATAEALALGTRHGLDPRALYAVIQSSTGQSWMC 194
Query: 377 EVYCPVPGLVPT--APSSRNYDGGFKNELMVKDLELA--SGMALGIRSPIPLGAVAXQLY 210
+ CP+P + PS+ Y GF+ E+MVKDL+L S +G+ + A+A
Sbjct: 195 DHVCPIPNVQTQYWVPSNSGYRPGFRTEMMVKDLDLGVRSAAEVGVEPTMARAALAVWER 254
Query: 209 RIVQSRGYGQKDFSFVF 159
V R G +D S V+
Sbjct: 255 AAVDERCRG-RDGSSVY 270
>UniRef50_Q1N6I0 Cluster: Putative oxidoreductase protein; n=1;
Oceanobacter sp. RED65|Rep: Putative oxidoreductase
protein - Oceanobacter sp. RED65
Length = 289
Score = 81.0 bits (191), Expect = 4e-14
Identities = 55/184 (29%), Positives = 89/184 (48%)
Frame = -3
Query: 692 KGLGFTXAPVXGGVMGAQNVTXAFMAGGXKEDFERSLXLLKVMGXKQFHCGQIGSGQVAK 513
K + + APV GG GA + M GG ER+ + + H G IGSGQ+ K
Sbjct: 113 KQVDYVDAPVSGGEQGAISGQLTIMCGGQALAAERAQGITQAYSKSFTHMGPIGSGQLTK 172
Query: 512 LTNNMLMGITGMATAECMNMGIKMGLEPKVLLDVLNNSSARSWSTEVYCPVPGLVPTAPS 333
+ N + + A AE ++ G + GL+ + ++ V+ + +A SW + T
Sbjct: 173 MVNQICVAGLIEALAEGIHFGQQAGLDMEKVMKVVGSGAASSWQLQ------NRYQTMLE 226
Query: 332 SRNYDGGFKNELMVKDLELASGMALGIRSPIPLGAVAXQLYRIVQSRGYGQKDFSFVFQL 153
+ YD GF + M KDLE+ A + + +P A+ QLY +Q G+GQ D S + +
Sbjct: 227 DQ-YDFGFAVDHMRKDLEICLKEAKKMNTSLPSTAMVDQLYGELQQSGHGQLDTSSLLKR 285
Query: 152 LKEE 141
L+ +
Sbjct: 286 LQNK 289
>UniRef50_Q12CU4 Cluster: 2-hydroxy-3-oxopropionate reductase; n=17;
Proteobacteria|Rep: 2-hydroxy-3-oxopropionate reductase
- Polaromonas sp. (strain JS666 / ATCC BAA-500)
Length = 298
Score = 81.0 bits (191), Expect = 4e-14
Identities = 59/184 (32%), Positives = 83/184 (45%)
Frame = -3
Query: 689 GLGFTXAPVXGGVMGAQNVTXAFMAGGXKEDFERSLXLLKVMGXKQFHCGQIGSGQVAKL 510
G+ PV GG +GA+ T MAGG DFERSL LLKV G + H G GSGQ+ KL
Sbjct: 120 GIAHLDTPVSGGTVGAEQGTLVIMAGGKPADFERSLPLLKVFG-RATHVGPHGSGQLTKL 178
Query: 509 TNNMLMGITGMATAECMNMGIKMGLEPKVLLDVLNNSSARSWSTEVYCPVPGLVPTAPSS 330
N M++GIT A AE + K G + + + + A S +++
Sbjct: 179 ANQMIVGITIGAVAEALLFATKGGADMAKVKEAITGGFADSRVLQLH-------GQRMVE 231
Query: 329 RNYDGGFKNELMVKDLELASGMALGIRSPIPLGAVAXQLYRIVQSRGYGQKDFSFVFQLL 150
R++ + + +KD+ A A I P+ + QLY G D S +F L
Sbjct: 232 RDFAPRARLSIQLKDMRNALATAQEIGFDAPITGLFEQLYAEGVEHGLTDLDQSGLFVEL 291
Query: 149 KEEN 138
N
Sbjct: 292 ASRN 295
>UniRef50_A1WM48 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=1;
Verminephrobacter eiseniae EF01-2|Rep:
3-hydroxyisobutyrate dehydrogenase - Verminephrobacter
eiseniae (strain EF01-2)
Length = 301
Score = 81.0 bits (191), Expect = 4e-14
Identities = 56/183 (30%), Positives = 91/183 (49%), Gaps = 1/183 (0%)
Frame = -3
Query: 692 KGLGFTXAPVXGGVMGAQNVTXAFMAGGXKEDFERSLXLLKVMGXKQFHCGQIGSGQVAK 513
+G+ + +PV GG+ GA+ T A M + ++ +LK G + G GQ K
Sbjct: 114 RGIAYVDSPVSGGIGGAERGTLAVMTACPQPLYDELAPVLKNFGRLFYMGAGPGLGQTMK 173
Query: 512 LTNNMLMGITGMATAECMNMGIKMGLEPKVLLDVLNNSSARSWSTEVYCPVPGLVPTAPS 333
L NN+L T+E M MG K GL+P V+L+V+N S R+ +T P L T
Sbjct: 174 LANNLLSAAAVAITSEAMAMGAKAGLDPGVMLEVINAGSGRNSATMEKFPKAVLTGT--- 230
Query: 332 SRNYDGGFKNELMVKDLELASGMALGIRSPIPLGAVAXQLYRIVQSRGYGQ-KDFSFVFQ 156
++ GF L KD+ L + + P+ +GA ++ +V + YG+ D++ V +
Sbjct: 231 ---FNIGFAARLACKDVRLCLEESEALGVPMVVGAAVREML-VVTNAVYGKDADYTDVAR 286
Query: 155 LLK 147
LL+
Sbjct: 287 LLE 289
>UniRef50_A1B741 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=3;
Bacteria|Rep: 3-hydroxyisobutyrate dehydrogenase -
Paracoccus denitrificans (strain Pd 1222)
Length = 309
Score = 80.6 bits (190), Expect = 5e-14
Identities = 58/184 (31%), Positives = 85/184 (46%), Gaps = 1/184 (0%)
Frame = -3
Query: 692 KGLGFTXAPVXGGVMGAQNVTXAFMAGGXKEDFERSLXLLKVMGXKQFHCGQIGSGQVAK 513
KG+ F APV GG GA + A GG +E ++R L L+ M + + G IG+G +AK
Sbjct: 111 KGIHFIDAPVSGGPAGAASGQLAIWCGGEREVYDRCLPWLEKMADQPRYIGDIGAGTIAK 170
Query: 512 LTNNMLMGITGMATAECMNMGIKMGLEPKVLLDVLNNSSARSWSTEVYCPVPGLVPTAPS 333
L NNM AE ++MG+K GLEP L + + +A +Y + A
Sbjct: 171 LVNNMASTAIISVLAEALSMGVKAGLEPGPLWEAIRTGAA--GRMRMYDNIGRRFMQA-- 226
Query: 332 SRNYD-GGFKNELMVKDLELASGMALGIRSPIPLGAVAXQLYRIVQSRGYGQKDFSFVFQ 156
YD F L+ KD LA + P+ L + R +RG+G++D
Sbjct: 227 --KYDPPSFALRLIHKDASLALQVGRDFGVPMRLCTLVESDIREALNRGWGERDSQSYLA 284
Query: 155 LLKE 144
L +E
Sbjct: 285 LQQE 288
>UniRef50_A0G5F9 Cluster: 6-phosphogluconate dehydrogenase,
NAD-binding; n=2; Burkholderia|Rep: 6-phosphogluconate
dehydrogenase, NAD-binding - Burkholderia phymatum
STM815
Length = 307
Score = 80.6 bits (190), Expect = 5e-14
Identities = 58/176 (32%), Positives = 86/176 (48%), Gaps = 1/176 (0%)
Frame = -3
Query: 692 KGLGFTXAPVXGGVMGAQNVTXAFMAGGXKEDFERSLXLLKVMGXKQFHCG-QIGSGQVA 516
KG+ APV GG GA+ T A MA G E L V+G K F G + G GQ+
Sbjct: 122 KGVETVDAPVSGGAAGAKKGTLAIMAAGSPVALEEVRGLFDVLG-KAFVVGDKAGQGQLL 180
Query: 515 KLTNNMLMGITGMATAECMNMGIKMGLEPKVLLDVLNNSSARSWSTEVYCPVPGLVPTAP 336
KL NNML T+E G++ GL+P+V++ V+N S ++ +T P L P
Sbjct: 181 KLLNNMLSSTAFAITSEAFVAGVRGGLDPEVMMSVINAGSGKNGATLDKFPKHVL----P 236
Query: 335 SSRNYDGGFKNELMVKDLELASGMALGIRSPIPLGAVAXQLYRIVQSRGYGQKDFS 168
S +D GF + KD+ LA + P+ +G+VA Q++ + +D +
Sbjct: 237 GS--FDFGFPVGSVCKDIGLAVDECQALGVPMWVGSVARQMWNYAAMQDGAARDMT 290
>UniRef50_UPI00003C03F8 Cluster: PREDICTED: similar to CG4747-PA;
n=1; Apis mellifera|Rep: PREDICTED: similar to CG4747-PA
- Apis mellifera
Length = 413
Score = 80.2 bits (189), Expect = 6e-14
Identities = 54/182 (29%), Positives = 87/182 (47%), Gaps = 4/182 (2%)
Frame = -3
Query: 692 KGLGFTXAPVXGGVMGAQNVTXAFMAGGXKEDFERSLXLLKVMGXKQFHCGQIGSGQVAK 513
KG + A V G AQ T +A G + F+ + MG F+ G++G+
Sbjct: 238 KGGRYLEAQVQGSKTQAQEGTLVILAAGDRTLFDECQSCFEAMGKNSFYLGEVGNASKMN 297
Query: 512 LTNNMLMGITGMATAECMNMGIKMGLEPKVLLDVLNNSSARSWSTEVYCPVPGLVPTAPS 333
L ++ G+T AE M + + GL+ K +L+VL T + C P ++ +
Sbjct: 298 LVLQLMAGVTLAGLAESMALADRAGLQQKDVLEVLE-------LTSLAC--PAILDKGKA 348
Query: 332 SRNYDGGFKNEL----MVKDLELASGMALGIRSPIPLGAVAXQLYRIVQSRGYGQKDFSF 165
+GGF +L M KDL L+ GM+ + P+PL A A ++Y+ + GYG+ D S
Sbjct: 349 I--IEGGFPTQLPLQHMQKDLRLSLGMSDQLEQPLPLAAAANEVYKHAKRLGYGEHDASA 406
Query: 164 VF 159
V+
Sbjct: 407 VY 408
>UniRef50_A0LMG6 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=9;
cellular organisms|Rep: 3-hydroxyisobutyrate
dehydrogenase - Syntrophobacter fumaroxidans (strain DSM
10017 / MPOB)
Length = 309
Score = 80.2 bits (189), Expect = 6e-14
Identities = 49/164 (29%), Positives = 85/164 (51%)
Frame = -3
Query: 671 APVXGGVMGAQNVTXAFMAGGXKEDFERSLXLLKVMGXKQFHCGQIGSGQVAKLTNNMLM 492
APV GG +GA+N + M GG +E + +L+ MG + G GSGQ AK+ N +++
Sbjct: 131 APVSGGDVGARNAALSIMLGGDREVVDAIRPILEAMGKNLVYLGPAGSGQHAKVCNQIVI 190
Query: 491 GITGMATAECMNMGIKMGLEPKVLLDVLNNSSARSWSTEVYCPVPGLVPTAPSSRNYDGG 312
T + E + G K GL+ +L + + +A+ W+ + L P R++ G
Sbjct: 191 TGTMIGVCESLMYGFKAGLDLPTMLSSIKDGAAKCWTLD------NLAPRI-LRRDFAPG 243
Query: 311 FKNELMVKDLELASGMALGIRSPIPLGAVAXQLYRIVQSRGYGQ 180
F + +KD+ +A A + +P A+ QLY V+++G+G+
Sbjct: 244 FFVDHFIKDMGIALQEAARMGLSLPGLALTHQLYLAVKAQGHGK 287
>UniRef50_Q92D17 Cluster: Lin1004 protein; n=10; Bacilli|Rep:
Lin1004 protein - Listeria innocua
Length = 286
Score = 79.8 bits (188), Expect = 8e-14
Identities = 48/172 (27%), Positives = 85/172 (49%)
Frame = -3
Query: 692 KGLGFTXAPVXGGVMGAQNVTXAFMAGGXKEDFERSLXLLKVMGXKQFHCGQIGSGQVAK 513
KG+G APV GG +GA+N T A M GG ++ F + + +++G G GSGQ K
Sbjct: 112 KGIGVLDAPVSGGDIGAKNGTLAIMVGGAEDVFLKVKPIFEILGSSVILQGDAGSGQHTK 171
Query: 512 LTNNMLMGITGMATAECMNMGIKMGLEPKVLLDVLNNSSARSWSTEVYCPVPGLVPTAPS 333
+ N + + + E + + GL P +LD ++ +A SWS + L+P
Sbjct: 172 MVNQIAIASNMIGVTEAIIYAERAGLNPSRVLDSISGGAAGSWS------LTNLIPRVLQ 225
Query: 332 SRNYDGGFKNELMVKDLELASGMALGIRSPIPLGAVAXQLYRIVQSRGYGQK 177
++ GF + +KD+ +A A + +P +A Q+Y+ + +G ++
Sbjct: 226 D-DFSPGFFIKHFIKDMGIALSEAKQMGLELPGLTLAEQMYQTLAEQGLSEE 276
>UniRef50_Q8PK98 Cluster: 3-hydroxyisobutirate dehydrogenase; n=3;
Proteobacteria|Rep: 3-hydroxyisobutirate dehydrogenase -
Xanthomonas axonopodis pv. citri
Length = 300
Score = 79.8 bits (188), Expect = 8e-14
Identities = 57/186 (30%), Positives = 87/186 (46%), Gaps = 1/186 (0%)
Frame = -3
Query: 695 RKGLGFTXAPVXGGVMGAQNVTXAFMAGGXKEDFERSLXLLKVMGXKQFHCG-QIGSGQV 519
R + F APV GG A MA G +ER+ LL +G F+ G + GQ
Sbjct: 112 RADVSFLSAPVSGGTAAAAQGVLTVMAAGPLAAYERARPLLDAVGRHIFYLGGDVRLGQT 171
Query: 518 AKLTNNMLMGITGMATAECMNMGIKMGLEPKVLLDVLNNSSARSWSTEVYCPVPGLVPTA 339
KL NN L +A+ E + G K GL+ + +LDV+N SS R ++T + G +
Sbjct: 172 LKLINNTLYASAMLASCEALVCGAKAGLDARTMLDVINRSSGRCFATME--RLHGAL--- 226
Query: 338 PSSRNYDGGFKNELMVKDLELASGMALGIRSPIPLGAVAXQLYRIVQSRGYGQKDFSFVF 159
R++ F EL+ KD++L A + P+ +G A QL + G G+ D
Sbjct: 227 --DRSFPVRFTTELLRKDVQLGLMAADELGVPMHVGKAALQLLDQAVADGLGEADNIAAI 284
Query: 158 QLLKEE 141
Q ++ +
Sbjct: 285 QSIERQ 290
>UniRef50_A3K497 Cluster: Probable 6-phosphogluconate dehydrogenase
protein; n=1; Sagittula stellata E-37|Rep: Probable
6-phosphogluconate dehydrogenase protein - Sagittula
stellata E-37
Length = 298
Score = 79.8 bits (188), Expect = 8e-14
Identities = 50/154 (32%), Positives = 82/154 (53%), Gaps = 3/154 (1%)
Frame = -3
Query: 692 KGLGFTXAPVXGGVMGAQNVTXAFMAGGXKED-FERSLXLLKVMGXKQFHCGQIGSGQVA 516
+G APV G GA+ FM G + ER+ +L +G + FH G +G+G
Sbjct: 116 RGCHLVDAPVSGARAGAEAADLVFMIGCDDDAVLERTRAVLSCLGNRLFHLGPVGAGHAM 175
Query: 515 KLTNNMLMGITGMATAECMNMGIKMGLEPKVLLDVLNNSSARSWSTEVYCPVPGLVPTAP 336
K NN + +A AE M +G ++GL+P ++DVLN S+ R++STEV +P ++
Sbjct: 176 KALNNYVSAAGYVAAAEAMIIGTEVGLDPAQIVDVLNVSTGRNFSTEV--SMPRIL---- 229
Query: 335 SSRNYDGGFKNELMVKDLELAS--GMALGIRSPI 240
+++ F EL KD+ +A+ G G+ +P+
Sbjct: 230 -RGDFERRFTLELYTKDVRIAANLGDRAGVTAPL 262
>UniRef50_Q5WBB8 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=1;
Bacillus clausii KSM-K16|Rep: 3-hydroxyisobutyrate
dehydrogenase - Bacillus clausii (strain KSM-K16)
Length = 283
Score = 79.4 bits (187), Expect = 1e-13
Identities = 58/180 (32%), Positives = 86/180 (47%), Gaps = 2/180 (1%)
Frame = -3
Query: 692 KGLGFTXAPVXGGVMGAQNVTXAFMAGGXKEDFERSLXLLKVMGXKQFHCGQIGSGQVAK 513
KG+ + PV GG GA T M GG K+ + LL ++G + G G+GQ K
Sbjct: 112 KGIYYLDCPVSGGPAGADAGTLTIMVGGDKQAYFSVKPLLDILGDTILYVGDSGAGQTVK 171
Query: 512 LTNNMLM-GITGMATAECMNMGIKMGLEPKVLLDVLNNSSARSWSTEVYCPVPGLVPTAP 336
L NNML+ GIT + +E M + G+ ++L ++ SS + +V+ L+
Sbjct: 172 LCNNMLVAGITTL-LSETMAVASDHGVSRRLLAQIIQQSSGHNRVLDVF--GENLI---- 224
Query: 335 SSRNYDGG-FKNELMVKDLELASGMALGIRSPIPLGAVAXQLYRIVQSRGYGQKDFSFVF 159
S +YD F + M KDLEL ++ R P QLYR +G G KD + V+
Sbjct: 225 -SGSYDNVLFYLKHMAKDLELYMALSQDSRKPQHAAGTVNQLYRSALHQGKGDKDATAVY 283
>UniRef50_Q94B07 Cluster: Gamma hydroxybutyrate dehydrogenase; n=16;
cellular organisms|Rep: Gamma hydroxybutyrate
dehydrogenase - Arabidopsis thaliana (Mouse-ear cress)
Length = 289
Score = 79.4 bits (187), Expect = 1e-13
Identities = 58/184 (31%), Positives = 91/184 (49%), Gaps = 2/184 (1%)
Frame = -3
Query: 692 KGLGFTXAPVXGGVMGAQNVTXAFMAGGXKEDFERSLXLLKVMGXKQFHCGQIGSGQVAK 513
KG F PV G A++ +A G K FE S+ V+G + F+ GQ+G+G K
Sbjct: 111 KGGRFVEGPVSGSKKPAEDGQLIILAAGDKALFEESIPAFDVLGKRSFYLGQVGNGAKMK 170
Query: 512 LTNNMLMGITGMATAECMNMGIKMGLEPKVLLDVLNNSSARSWSTEVYCPVPGLVPTAPS 333
L NM+MG A +E + + K GL LLD+L+ + + ++ G P+
Sbjct: 171 LIVNMIMGSMMNAFSEGLVLADKSGLSSDTLLDILD---LGAMTNPMF---KGKGPSMTK 224
Query: 332 SRNYDGGFKNELMVKDLELASGMALGIRSPI--PLGAVAXQLYRIVQSRGYGQKDFSFVF 159
S +Y F + KD+ LA +ALG + + P+ A A + ++ +S G G DFS V
Sbjct: 225 S-SYPPAFPLKHQQKDMRLA--LALGDENAVSMPVAAAANEAFKKARSLGLGDLDFSAVI 281
Query: 158 QLLK 147
+ +K
Sbjct: 282 EAVK 285
>UniRef50_UPI0000E49FD0 Cluster: PREDICTED: similar to gamma
hydroxybutyrate dehydrogenase; n=3; Strongylocentrotus
purpuratus|Rep: PREDICTED: similar to gamma
hydroxybutyrate dehydrogenase - Strongylocentrotus
purpuratus
Length = 219
Score = 78.2 bits (184), Expect = 3e-13
Identities = 52/177 (29%), Positives = 81/177 (45%)
Frame = -3
Query: 680 FTXAPVXGGVMGAQNVTXAFMAGGXKEDFERSLXLLKVMGXKQFHCGQIGSGQVAKLTNN 501
F APV G V A + +A G KE ++ + MG K F+ G+ KL N
Sbjct: 48 FMEAPVCGSVQPAMEGSLIIIAAGDKELYDECESCFQAMGKKAFYLSDTGNAARMKLVIN 107
Query: 500 MLMGITGMATAECMNMGIKMGLEPKVLLDVLNNSSARSWSTEVYCPVPGLVPTAPSSRNY 321
M++G AE M + K GL VLLD+LN S + P+ A + Y
Sbjct: 108 MIIGGVMCCFAEGMALADKSGLSQSVLLDILNLGSIAN-------PLISGKGKAILANKY 160
Query: 320 DGGFKNELMVKDLELASGMALGIRSPIPLGAVAXQLYRIVQSRGYGQKDFSFVFQLL 150
F + KDL+LA M+ + P+P+ + + ++ ++ G G KD S +++ L
Sbjct: 161 PPAFPLKYQQKDLKLALAMSEQVDQPLPVASAVNEQFKRAKNMGLGDKDTSAIYKSL 217
>UniRef50_Q2JEV5 Cluster: 6-phosphogluconate dehydrogenase,
NAD-binding; n=6; Bacteria|Rep: 6-phosphogluconate
dehydrogenase, NAD-binding - Frankia sp. (strain CcI3)
Length = 302
Score = 78.2 bits (184), Expect = 3e-13
Identities = 54/178 (30%), Positives = 79/178 (44%)
Frame = -3
Query: 689 GLGFTXAPVXGGVMGAQNVTXAFMAGGXKEDFERSLXLLKVMGXKQFHCGQIGSGQVAKL 510
G+GF APV GG GA + M GG E ER+ +L G G +GSGQ+ K+
Sbjct: 113 GVGFVDAPVSGGEAGAMAGRLSIMCGGDPETIERARPVLAAYGATITRIGPVGSGQLTKM 172
Query: 509 TNNMLMGITGMATAECMNMGIKMGLEPKVLLDVLNNSSARSWSTEVYCPVPGLVPTAPSS 330
N +L+ AE +N I GL+ ++L + +A SW Y G
Sbjct: 173 VNQILVAGAVEGAAEAINFAIAAGLDTDLVLSAVAGGAANSW----YLANRGQTMVRD-- 226
Query: 329 RNYDGGFKNELMVKDLELASGMALGIRSPIPLGAVAXQLYRIVQSRGYGQKDFSFVFQ 156
+D GF + M KDL + A P+P+ +A + Q+ G G D + V +
Sbjct: 227 -EFDFGFAVDWMRKDLRICLAEAGRRGIPLPMIELAERDLAAAQADGEGGLDTTVVIR 283
>UniRef50_O66454 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=3;
cellular organisms|Rep: 3-hydroxyisobutyrate
dehydrogenase - Aquifex aeolicus
Length = 288
Score = 78.2 bits (184), Expect = 3e-13
Identities = 50/183 (27%), Positives = 85/183 (46%)
Frame = -3
Query: 689 GLGFTXAPVXGGVMGAQNVTXAFMAGGXKEDFERSLXLLKVMGXKQFHCGQIGSGQVAKL 510
G + APV G V+ A + GG KE FE + L + ++ G+ G G KL
Sbjct: 113 GAFYLDAPVLGSVIPALKGELTIVVGGDKEKFEENKPLFEKFCRAIYYLGEAGMGSKMKL 172
Query: 509 TNNMLMGITGMATAECMNMGIKMGLEPKVLLDVLNNSSARSWSTEVYCPVPGLVPTAPSS 330
NN+++G AE + +G K G++ + L++VLN+ + +S+ +V
Sbjct: 173 VNNIVLGGIMEVLAEAIAIGEKAGIDKETLINVLNDGAGKSYILDV-------KKKKLLE 225
Query: 329 RNYDGGFKNELMVKDLELASGMALGIRSPIPLGAVAXQLYRIVQSRGYGQKDFSFVFQLL 150
++ F L+ KDL A + + A + Y + + G+G DFS V++L
Sbjct: 226 EDFSTHFSVNLIYKDLHYAQDLIKDLGLFSFTTAAVKETYGLARKEGFGNLDFSAVYKLF 285
Query: 149 KEE 141
KE+
Sbjct: 286 KED 288
>UniRef50_A5GPC0 Cluster: Hydroxyacid dehydrogenase/reductase family
protein; n=14; Cyanobacteria|Rep: Hydroxyacid
dehydrogenase/reductase family protein - Synechococcus
sp. (strain WH7803)
Length = 302
Score = 78.2 bits (184), Expect = 3e-13
Identities = 51/175 (29%), Positives = 84/175 (48%)
Frame = -3
Query: 692 KGLGFTXAPVXGGVMGAQNVTXAFMAGGXKEDFERSLXLLKVMGXKQFHCGQIGSGQVAK 513
+G+ + APV GG GA+ T + GG D +R++ +L+ +G H G +GSGQ K
Sbjct: 126 RGVRYLDAPVTGGTEGAKAGTLTVLCGGSDADLDRAMPVLETIGGSIHHFGAVGSGQQVK 185
Query: 512 LTNNMLMGITGMATAECMNMGIKMGLEPKVLLDVLNNSSARSWSTEVYCPVPGLVPTAPS 333
N +L+ + A AE + +G + L + +++ L + +A SW+ E +A
Sbjct: 186 AVNQVLVAGSYAAVAEAIALGQHLQLPMQQVVNALRHGAAGSWALEHR-------SSAML 238
Query: 332 SRNYDGGFKNELMVKDLELASGMALGIRSPIPLGAVAXQLYRIVQSRGYGQKDFS 168
S +Y GFK L KDL +A A +P+ + + + G G D S
Sbjct: 239 SDHYPLGFKLALHHKDLGIALQAAAEAGLDLPITQAVQAQEQTLMNAGLGDADVS 293
>UniRef50_A1UP64 Cluster: 6-phosphogluconate dehydrogenase,
NAD-binding; n=3; Mycobacterium|Rep: 6-phosphogluconate
dehydrogenase, NAD-binding - Mycobacterium sp. (strain
KMS)
Length = 305
Score = 78.2 bits (184), Expect = 3e-13
Identities = 53/182 (29%), Positives = 83/182 (45%)
Frame = -3
Query: 692 KGLGFTXAPVXGGVMGAQNVTXAFMAGGXKEDFERSLXLLKVMGXKQFHCGQIGSGQVAK 513
K + F APV GG GA A M GG ++ R+ +L + H G +G+GQ+ K
Sbjct: 111 KDIAFVDAPVSGGEAGAIAGALAVMMGGDEDAVRRAATVLDAVAATSVHVGPVGAGQLVK 170
Query: 512 LTNNMLMGITGMATAECMNMGIKMGLEPKVLLDVLNNSSARSWSTEVYCPVPGLVPTAPS 333
N ML+ E + + + G++ L VL A S E P
Sbjct: 171 AANQMLVAGNIALVGEAVTLLQRTGVDVDAALAVLGGGLAASKVLEAKAP-------KML 223
Query: 332 SRNYDGGFKNELMVKDLELASGMALGIRSPIPLGAVAXQLYRIVQSRGYGQKDFSFVFQL 153
+R++ GF+ +L KDL++A A R +PL + QL + ++S G G D S + +
Sbjct: 224 ARDFAPGFRIDLHYKDLKIALAAAEQARIAVPLTGIITQLVQALRSAGDGGLDHSALIKA 283
Query: 152 LK 147
L+
Sbjct: 284 LE 285
>UniRef50_Q3W9W7 Cluster: 6-phosphogluconate dehydrogenase, NAD
binding domain; n=2; Frankia sp. EAN1pec|Rep:
6-phosphogluconate dehydrogenase, NAD binding domain -
Frankia sp. EAN1pec
Length = 286
Score = 77.8 bits (183), Expect = 3e-13
Identities = 52/161 (32%), Positives = 74/161 (45%), Gaps = 1/161 (0%)
Frame = -3
Query: 689 GLGFTXAPVXGGVMGAQNVTXAFMAGGXKEDFERSLXLLKVMGXKQFHCG-QIGSGQVAK 513
G+G+ APV GGV GA+ T M G + R +L + ++ G + G Q K
Sbjct: 110 GIGYVDAPVSGGVTGARARTLTVMYAGTDDACARVEPVLAALSDRRRRVGDRPGLAQALK 169
Query: 512 LTNNMLMGITGMATAECMNMGIKMGLEPKVLLDVLNNSSARSWSTEVYCPVPGLVPTAPS 333
L NN L + AT+E + G GL+ +LDVLN +S ++ +T P L
Sbjct: 170 LANNFLAAVALAATSEAVAFGTSAGLDMGTMLDVLNTASGQNNATAEKFPRQVL------ 223
Query: 332 SRNYDGGFKNELMVKDLELASGMALGIRSPIPLGAVAXQLY 210
+ Y GF N LM KDL L + P LG V ++
Sbjct: 224 TERYSAGFANSLMAKDLRLYLQEVRELDGPTSLGTVTSSVW 264
>UniRef50_Q183P5 Cluster: 2-hydroxy-3-oxopropionate reductase; n=5;
Bacteria|Rep: 2-hydroxy-3-oxopropionate reductase -
Clostridium difficile (strain 630)
Length = 296
Score = 77.8 bits (183), Expect = 3e-13
Identities = 49/182 (26%), Positives = 91/182 (50%)
Frame = -3
Query: 689 GLGFTXAPVXGGVMGAQNVTXAFMAGGXKEDFERSLXLLKVMGXKQFHCGQIGSGQVAKL 510
GL F +PV GG A + T AFMAGG +E +++ +MG G GSG V KL
Sbjct: 111 GLEFIDSPVSGGEPKAIDGTLAFMAGGKEEIYKKVEPFFNIMGSSSILIGDNGSGSVTKL 170
Query: 509 TNNMLMGITGMATAECMNMGIKMGLEPKVLLDVLNNSSARSWSTEVYCPVPGLVPTAPSS 330
TN +++ +T A +E + K G +P+ + + A ST + +P ++ +
Sbjct: 171 TNQVIVNLTIAAVSEAFVLAAKAGADPEKVYKAIRGGLA--GSTILDAKIPMIM-----N 223
Query: 329 RNYDGGFKNELMVKDLELASGMALGIRSPIPLGAVAXQLYRIVQSRGYGQKDFSFVFQLL 150
R++ G K + +KD++ A + P+P+ + ++ + ++ G+ + D S + Q
Sbjct: 224 RDFKPGGKISINLKDIKNVMQTAHNLDVPLPMTSQLLEIMQTLKVHGHLEDDHSGIAQYF 283
Query: 149 KE 144
++
Sbjct: 284 EK 285
>UniRef50_A3X9R7 Cluster: 3-hydroxyisobutyrate dehydrogenase family
protein; n=2; Rhodobacterales|Rep: 3-hydroxyisobutyrate
dehydrogenase family protein - Roseobacter sp. MED193
Length = 300
Score = 77.4 bits (182), Expect = 5e-13
Identities = 53/184 (28%), Positives = 82/184 (44%)
Frame = -3
Query: 689 GLGFTXAPVXGGVMGAQNVTXAFMAGGXKEDFERSLXLLKVMGXKQFHCGQIGSGQVAKL 510
G F PV GG +GA+ T + GG + F + LL+ M K H G G+G K+
Sbjct: 122 GYTFLDGPVSGGPLGARTGTMTMVVGGDEAGFTKVRPLLEKMTGKLVHIGPSGAGHTVKI 181
Query: 509 TNNMLMGITGMATAECMNMGIKMGLEPKVLLDVLNNSSARSWSTEVYCPVPGLVPTAPSS 330
NN+L + +E M + G+ LL +N S RS +EV P ++
Sbjct: 182 ANNLLCAANLVLMSEMAQMAERAGISLTELLTGINAGSGRSGVSEVN------FPKWITN 235
Query: 329 RNYDGGFKNELMVKDLELASGMALGIRSPIPLGAVAXQLYRIVQSRGYGQKDFSFVFQLL 150
YD GF LM KD+ LA+G+A + +P ++ + DF+ +++
Sbjct: 236 EAYDSGFTMGLMRKDVGLATGLAERLGIDLPATREIAAIWENSREILDDSADFNEIYKYR 295
Query: 149 KEEN 138
K N
Sbjct: 296 KRSN 299
>UniRef50_Q47AR2 Cluster: NADP oxidoreductase, coenzyme
F420-dependent:6-phosphogluconate dehydrogenase,
NAD-binding; n=1; Dechloromonas aromatica RCB|Rep: NADP
oxidoreductase, coenzyme
F420-dependent:6-phosphogluconate dehydrogenase,
NAD-binding - Dechloromonas aromatica (strain RCB)
Length = 287
Score = 77.0 bits (181), Expect = 6e-13
Identities = 53/181 (29%), Positives = 83/181 (45%)
Frame = -3
Query: 689 GLGFTXAPVXGGVMGAQNVTXAFMAGGXKEDFERSLXLLKVMGXKQFHCGQIGSGQVAKL 510
G+ F APV GG +GA + + MAGG F ++ + MG H G G+GQVAK
Sbjct: 109 GIDFIDAPVSGGEVGAIAGSLSIMAGGSDAAFAKAKPAFECMGKNIVHVGASGAGQVAKA 168
Query: 509 TNNMLMGITGMATAECMNMGIKMGLEPKVLLDVLNNSSARSWSTEVYCPVPGLVPTAPSS 330
N ++ G+ +A AE K G++ + + L A S E +
Sbjct: 169 ANQIVTGMGVLAVAEAFAFAAKNGVDSAKVREALLGGFAYSKILENH-------GQRMLD 221
Query: 329 RNYDGGFKNELMVKDLELASGMALGIRSPIPLGAVAXQLYRIVQSRGYGQKDFSFVFQLL 150
RN+ GFK+ + KDL + A + +P A Q++ + G G++D V +LL
Sbjct: 222 RNFKPGFKSWMHEKDLNIVMQTAHELGLCLPGSAATAQMFNAMVGSGLGEEDSIAVLKLL 281
Query: 149 K 147
+
Sbjct: 282 E 282
>UniRef50_A3WMG5 Cluster: Probable 3-hydroxyisobutyrate
dehydrogenase; n=1; Idiomarina baltica OS145|Rep:
Probable 3-hydroxyisobutyrate dehydrogenase - Idiomarina
baltica OS145
Length = 284
Score = 77.0 bits (181), Expect = 6e-13
Identities = 54/182 (29%), Positives = 87/182 (47%), Gaps = 1/182 (0%)
Frame = -3
Query: 695 RKGLGFTXAPVXGGVMGAQNVTXAFMAGGXKEDFERSLXLLKVMGXKQFHCGQIGSGQVA 516
++G APV G AQN ++ GG R+ +L +MG K H G++GSG +A
Sbjct: 112 QRGKQLIEAPVSGSRPQAQNAELVYLVGGDAHLVNRAEPVLSLMGKKVNHTGEMGSGALA 171
Query: 515 KLTNNMLMGITGMATAECMNMGIKMGLEPKVLLDVLNNSSARSWSTEVYCPVPGLVPTAP 336
KL N LMGI AE + M + G +P +L+ ++ +T V+ G+V +
Sbjct: 172 KLVTNTLMGIQVTTIAELIGMLKRQGQDPDAILEAVS-------TTPVWSKTAGIVRKSM 224
Query: 335 SSRNYDGGFKNELMVKDLELASGMALGIRSPI-PLGAVAXQLYRIVQSRGYGQKDFSFVF 159
S YD F +L+ KDL G L + P+ + A ++ Q + G+ + + V
Sbjct: 225 VSEAYDPQFPVDLIEKDL----GYCLQAADQVAPMTSAARTVFNEAQEQQLGEWNMTVVA 280
Query: 158 QL 153
+L
Sbjct: 281 KL 282
>UniRef50_Q019Z7 Cluster: Oxidoreductase-like; n=1; Ostreococcus
tauri|Rep: Oxidoreductase-like - Ostreococcus tauri
Length = 325
Score = 76.6 bits (180), Expect = 8e-13
Identities = 54/182 (29%), Positives = 83/182 (45%)
Frame = -3
Query: 689 GLGFTXAPVXGGVMGAQNVTXAFMAGGXKEDFERSLXLLKVMGXKQFHCGQIGSGQVAKL 510
G F APV G A++ F+ G + + R L VMG F G +G G KL
Sbjct: 151 GAEFLEAPVSGSKKPAEDGALIFLCAGDEGLYTRCTDPLDVMGKAHFFLGDVGQGAKMKL 210
Query: 509 TNNMLMGITGMATAECMNMGIKMGLEPKVLLDVLNNSSARSWSTEVYCPVPGLVPTAPSS 330
NM+MG A AE + + K L + LL V++ + S P+ L + +
Sbjct: 211 VVNMIMGSMMGAFAEGLTLADKSDLSQETLLQVISLGAIAS-------PMFALKGPSMVA 263
Query: 329 RNYDGGFKNELMVKDLELASGMALGIRSPIPLGAVAXQLYRIVQSRGYGQKDFSFVFQLL 150
NY F + KD+ LA +A + +P+ A A +LY+ + G +DFS V + +
Sbjct: 264 GNYPPAFPLKHQQKDMRLAIALADELAQDMPVAAAANELYKRARRDGCDDEDFSAVLKAV 323
Query: 149 KE 144
K+
Sbjct: 324 KK 325
>UniRef50_Q0RCX7 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=1;
Frankia alni ACN14a|Rep: 3-hydroxyisobutyrate
dehydrogenase - Frankia alni (strain ACN14a)
Length = 313
Score = 76.2 bits (179), Expect = 1e-12
Identities = 54/179 (30%), Positives = 80/179 (44%)
Frame = -3
Query: 689 GLGFTXAPVXGGVMGAQNVTXAFMAGGXKEDFERSLXLLKVMGXKQFHCGQIGSGQVAKL 510
G+GF APV GG GA+ + M GG + ER +L G G +G+GQ+ K+
Sbjct: 113 GVGFVDAPVSGGQAGAEAGRLSVMCGGEVDTVERVRPVLAAYGATITRIGPVGTGQLTKM 172
Query: 509 TNNMLMGITGMATAECMNMGIKMGLEPKVLLDVLNNSSARSWSTEVYCPVPGLVPTAPSS 330
N +L+ AE +N GL+ +L ++ +A SW + T
Sbjct: 173 VNQILVAGAIEGAAEALNFAAAAGLDLDQVLPAVSGGAASSWY------LTNRAATMIRD 226
Query: 329 RNYDGGFKNELMVKDLELASGMALGIRSPIPLGAVAXQLYRIVQSRGYGQKDFSFVFQL 153
+D GF + M KDL + A P+PL +A Q+RG GQ D + V +L
Sbjct: 227 -EFDFGFAVDWMRKDLRICLAEAARRGVPVPLTELAEGDLAASQARGDGQLDATAVIRL 284
>UniRef50_A5FTT0 Cluster: 6-phosphogluconate dehydrogenase,
NAD-binding; n=3; Alphaproteobacteria|Rep:
6-phosphogluconate dehydrogenase, NAD-binding -
Acidiphilium cryptum (strain JF-5)
Length = 305
Score = 76.2 bits (179), Expect = 1e-12
Identities = 51/145 (35%), Positives = 75/145 (51%), Gaps = 2/145 (1%)
Frame = -3
Query: 671 APVXGGVMGAQNVTXAFMAGGXKEDFERSLXLLKVMGXKQFHCGQIGSGQVAKLTNNMLM 492
APV GGV A+ + M GG +D R+ LL++MG H G IG+GQ K NN++
Sbjct: 118 APVSGGVARAKTGDLSIMTGGSADDCARAETLLRLMGTTITHVGDIGAGQAMKALNNLVS 177
Query: 491 GITGMATAECMNMGIKMGLEPKVLLDVLNNSSARSWSTEVYCPVPGLVPTAPSSRNYDGG 312
+ E + +G + GL+P ++DVLN S+ + ST+ L SR ++
Sbjct: 178 AGGFLIGVEALLIGQRFGLDPAQMVDVLNASTGMNNSTQKKFRQFVL------SRKFNSD 231
Query: 311 FKNELMVKDLELA--SGMALGIRSP 243
F +LM KDL +A G GI +P
Sbjct: 232 FSLDLMAKDLSIALEVGRDGGIATP 256
>UniRef50_Q830A7 Cluster: 2-hydroxy-3-oxopropionate reductase; n=7;
Firmicutes|Rep: 2-hydroxy-3-oxopropionate reductase -
Enterococcus faecalis (Streptococcus faecalis)
Length = 296
Score = 75.8 bits (178), Expect = 1e-12
Identities = 47/162 (29%), Positives = 74/162 (45%)
Frame = -3
Query: 671 APVXGGVMGAQNVTXAFMAGGXKEDFERSLXLLKVMGXKQFHCGQIGSGQVAKLTNNMLM 492
APV GG +GA+N T M GG +E ++ L + K G G G GQ K+ N +++
Sbjct: 119 APVSGGDLGAKNGTLTIMVGGDQESYDTVLPIFKTFGKTFMLHGSAGKGQHTKMANQLMI 178
Query: 491 GITGMATAECMNMGIKMGLEPKVLLDVLNNSSARSWSTEVYCPVPGLVPTAPSSRNYDGG 312
T E + GL + +L+ + SA +WS Y P +Y G
Sbjct: 179 AGTMTGLTEMLVYANATGLTLEKVLETVGGGSAANWSLSNYGP-------RILKEDYTPG 231
Query: 311 FKNELMVKDLELASGMALGIRSPIPLGAVAXQLYRIVQSRGY 186
F + +KDL++A A + P+P A +LY + +G+
Sbjct: 232 FFVKHFIKDLKIALDEAKKLDLPLPATQKATELYESLADKGF 273
>UniRef50_Q7VYY0 Cluster: Putative oxidoreductase; n=4;
Bordetella|Rep: Putative oxidoreductase - Bordetella
pertussis
Length = 305
Score = 75.8 bits (178), Expect = 1e-12
Identities = 50/143 (34%), Positives = 69/143 (48%)
Frame = -3
Query: 692 KGLGFTXAPVXGGVMGAQNVTXAFMAGGXKEDFERSLXLLKVMGXKQFHCGQIGSGQVAK 513
+GL APV G V A T A MAG + D R +L+ MG H G +GS K
Sbjct: 121 RGLTLIDAPVSGAVAKASTGTLAIMAGAAEADLRRVRPILERMGAAIIHTGAVGSAHAMK 180
Query: 512 LTNNMLMGITGMATAECMNMGIKMGLEPKVLLDVLNNSSARSWSTEVYCPVPGLVPTAPS 333
NN + +A +E M + +M L+ +V DVLN SS R+ ++E ++P
Sbjct: 181 ALNNYVYAAGLLAVSEAMVIARRMELDLEVFTDVLNASSGRNVASETKLR-QFIIP---- 235
Query: 332 SRNYDGGFKNELMVKDLELASGM 264
Y+GGF LM KDL A +
Sbjct: 236 -GTYNGGFALALMAKDLGTAQSL 257
>UniRef50_Q39FA8 Cluster: 2-hydroxy-3-oxopropionate reductase; n=22;
Burkholderiales|Rep: 2-hydroxy-3-oxopropionate reductase
- Burkholderia sp. (strain 383) (Burkholderia cepacia
(strain ATCC 17760/ NCIB 9086 / R18194))
Length = 287
Score = 75.8 bits (178), Expect = 1e-12
Identities = 53/184 (28%), Positives = 84/184 (45%)
Frame = -3
Query: 689 GLGFTXAPVXGGVMGAQNVTXAFMAGGXKEDFERSLXLLKVMGXKQFHCGQIGSGQVAKL 510
G+G+ APV GGV GAQ T A MAGG D + L+ + H G G+GQ AKL
Sbjct: 105 GVGWVDAPVSGGVPGAQAGTLAVMAGGRAADLDAVRPLIDTYASRITHMGDAGAGQTAKL 164
Query: 509 TNNMLMGITGMATAECMNMGIKMGLEPKVLLDVLNNSSARSWSTEVYCPVPGLVPTAPSS 330
N ++ T A AE + + G++ L + L A W+ V + VP S
Sbjct: 165 CNQAIVTATVTAIAEAVGLAQASGIDAARLAEAL----AGGWADSVL--LQTFVPRMTSG 218
Query: 329 RNYDGGFKNELMVKDLELASGMALGIRSPIPLGAVAXQLYRIVQSRGYGQKDFSFVFQLL 150
+ G + KD++ + A + +P+ A Q+ R+ ++G DF+ ++
Sbjct: 219 GHPPIGALSTFQ-KDVDAIADAARDTGAVMPVSATVQQVLRLGAAQGLAGADFAAFIDIV 277
Query: 149 KEEN 138
+ N
Sbjct: 278 RPGN 281
>UniRef50_Q121N3 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=19;
Burkholderiales|Rep: 3-hydroxyisobutyrate dehydrogenase
- Polaromonas sp. (strain JS666 / ATCC BAA-500)
Length = 298
Score = 75.8 bits (178), Expect = 1e-12
Identities = 47/180 (26%), Positives = 84/180 (46%), Gaps = 1/180 (0%)
Frame = -3
Query: 689 GLGFTXAPVXGGVMGAQNVTXAFMAGGXKEDFERSLXLLKVMGXKQFHCGQ-IGSGQVAK 513
G+ + AP+ GG A M+ +E++ +L M K + G G+G K
Sbjct: 115 GIHYVDAPISGGAAKAAAGQMTVMSSARPAAYEKAGDVLAAMAGKVYRLGDCAGAGSKVK 174
Query: 512 LTNNMLMGITGMATAECMNMGIKMGLEPKVLLDVLNNSSARSWSTEVYCPVPGLVPTAPS 333
+ N +L G+ A AE M +G++ G++P L +V+ +S+ SW E
Sbjct: 175 IINQLLAGVHIAAAAEAMALGLREGVDPNALYEVITHSAGNSWMFENRM-------AHVL 227
Query: 332 SRNYDGGFKNELMVKDLELASGMALGIRSPIPLGAVAXQLYRIVQSRGYGQKDFSFVFQL 153
+ +Y ++ VKDL L A + P+PL + A Q++ + G+ ++D S V ++
Sbjct: 228 AGDYTPLSAVDIFVKDLGLVLDTARASKFPLPLSSTAHQMFMQASTAGFAREDDSAVIKI 287
>UniRef50_Q0SBQ9 Cluster: 2-hydroxy-3-oxopropionate reductase; n=12;
Actinomycetales|Rep: 2-hydroxy-3-oxopropionate reductase
- Rhodococcus sp. (strain RHA1)
Length = 294
Score = 75.8 bits (178), Expect = 1e-12
Identities = 54/175 (30%), Positives = 76/175 (43%)
Frame = -3
Query: 692 KGLGFTXAPVXGGVMGAQNVTXAFMAGGXKEDFERSLXLLKVMGXKQFHCGQIGSGQVAK 513
+G APV GG GA N + M GG EDFE + +L V+G H G GSGQ K
Sbjct: 112 RGFRLIDAPVSGGEAGAVNAALSIMVGGAPEDFESARPILDVVGKTVVHVGPNGSGQTVK 171
Query: 512 LTNNMLMGITGMATAECMNMGIKMGLEPKVLLDVLNNSSARSWSTEVYCPVPGLVPTAPS 333
N +++ AE + G++ ++VL A S V
Sbjct: 172 AANQLIVAGNIQLLAEAIIFLEAYGVDTAAAVEVLGGGLAGS-------AVLNQKAQKML 224
Query: 332 SRNYDGGFKNELMVKDLELASGMALGIRSPIPLGAVAXQLYRIVQSRGYGQKDFS 168
R+++ GF+ +L KDL + + A PLGAV QL ++ G G D S
Sbjct: 225 DRSFEPGFRIDLHHKDLGIVTSAAREAGVVTPLGAVLAQLMASARANGDGGLDHS 279
>UniRef50_Q6UCZ9 Cluster: Predicted oxidoreductase; n=2;
environmental samples|Rep: Predicted oxidoreductase -
uncultured marine proteobacterium ANT32C12
Length = 309
Score = 75.4 bits (177), Expect = 2e-12
Identities = 50/184 (27%), Positives = 86/184 (46%)
Frame = -3
Query: 695 RKGLGFTXAPVXGGVMGAQNVTXAFMAGGXKEDFERSLXLLKVMGXKQFHCGQIGSGQVA 516
+K + F AP+ GG GA++ + M GG K +E +L + G GSGQ+
Sbjct: 131 QKDVIFLDAPISGGQAGAESGQLSVMVGGDKASYESVKPILDNYSKFTKYMGPSGSGQLT 190
Query: 515 KLTNNMLMGITGMATAECMNMGIKMGLEPKVLLDVLNNSSARSWSTEVYCPVPGLVPTAP 336
K+ N + + A AE +N K+GL +++V+ +A+SW E
Sbjct: 191 KMVNQICIAGLVQALAEGVNFSEKVGLNTSDVMEVITKGAAQSWQMENRW-------ETM 243
Query: 335 SSRNYDGGFKNELMVKDLELASGMALGIRSPIPLGAVAXQLYRIVQSRGYGQKDFSFVFQ 156
YD GF + M KDL++ S A + + I + + + Y+ +Q G+ D S + +
Sbjct: 244 LKDEYDHGFAVDWMRKDLDIVSEQAGQVGANIEITEMVNKFYKDIQDLDGGRWDTSSLLK 303
Query: 155 LLKE 144
+K+
Sbjct: 304 RIKD 307
>UniRef50_Q930C6 Cluster: Probable; n=8; Alphaproteobacteria|Rep:
Probable - Rhizobium meliloti (Sinorhizobium meliloti)
Length = 295
Score = 74.9 bits (176), Expect = 2e-12
Identities = 49/185 (26%), Positives = 89/185 (48%)
Frame = -3
Query: 692 KGLGFTXAPVXGGVMGAQNVTXAFMAGGXKEDFERSLXLLKVMGXKQFHCGQIGSGQVAK 513
KGL + +P+ GG A MAGG +D + + +L+ + H G +G+GQ K
Sbjct: 113 KGLRWVDSPLSGGAPKALIGELTLMAGGTAQDVKDAHAVLRHVASNYTHMGSVGAGQTTK 172
Query: 512 LTNNMLMGITGMATAECMNMGIKMGLEPKVLLDVLNNSSARSWSTEVYCPVPGLVPTAPS 333
L N +L G+ +A AE + + G++ + L A S + Y +P V
Sbjct: 173 LINQVLCGLGFLAVAEATQLALDAGVDASKIPQALMGGRADSAILQEY--MPRFV----- 225
Query: 332 SRNYDGGFKNELMVKDLELASGMALGIRSPIPLGAVAXQLYRIVQSRGYGQKDFSFVFQL 153
+++Y + + MVKDL A +A + +PL A +++R++ + G G +D + + +
Sbjct: 226 TKDYRHTGRIDNMVKDLAGAQDLARRTNTAMPLTAACAEIHRMLTAAGLGGEDQAALMEF 285
Query: 152 LKEEN 138
+ N
Sbjct: 286 FRGPN 290
>UniRef50_UPI00015B4B33 Cluster: PREDICTED: similar to
3-hydroxyisobutyrate dehydrogenase; n=1; Nasonia
vitripennis|Rep: PREDICTED: similar to
3-hydroxyisobutyrate dehydrogenase - Nasonia vitripennis
Length = 512
Score = 74.1 bits (174), Expect = 4e-12
Identities = 50/182 (27%), Positives = 86/182 (47%), Gaps = 4/182 (2%)
Frame = -3
Query: 692 KGLGFTXAPVXGGVMGAQNVTXAFMAGGXKEDFERSLXLLKVMGXKQFHCGQIGSGQVAK 513
KG + A V G + ++ T +A G ++ F+ MG F+ G++G+
Sbjct: 337 KGARYLEAQVQGSKVQSEEGTLVILAAGDRQLFDDCNSCFGAMGKNTFYLGEVGNASKMN 396
Query: 512 LTNNMLMGITGMATAECMNMGIKMGLEPKVLLDVLNNSSARSWSTEVYCPVPGLVPTAPS 333
L ++ G+T AE M + + GL+ K +L++L T + C P ++ +
Sbjct: 397 LVLQLMAGVTLAGLAESMALADRAGLQQKDVLEILE-------LTSLAC--PAILDKGKA 447
Query: 332 SRNYDGGFKNEL----MVKDLELASGMALGIRSPIPLGAVAXQLYRIVQSRGYGQKDFSF 165
+GGF +L M KDL L+ M+ + PIPL A A ++Y+ + GY + D S
Sbjct: 448 I--IEGGFPTQLPLQHMQKDLRLSLSMSDQLEQPIPLAAAANEIYKHAKRLGYAEHDASA 505
Query: 164 VF 159
V+
Sbjct: 506 VY 507
>UniRef50_Q89R44 Cluster: Oxidoreductase; n=23; Bacteria|Rep:
Oxidoreductase - Bradyrhizobium japonicum
Length = 305
Score = 74.1 bits (174), Expect = 4e-12
Identities = 49/180 (27%), Positives = 78/180 (43%), Gaps = 1/180 (0%)
Frame = -3
Query: 689 GLGFTXAPVXGGVMGAQNVTXAFMAGGXKEDFERSLXLLKVMGXKQFHCGQI-GSGQVAK 513
G + AP+ GG A +A G F ++ L M K + G G G K
Sbjct: 120 GRHYLDAPISGGAQRAAQGELTILASGSPAAFAKARPALDAMAAKLYELGDAAGQGAAFK 179
Query: 512 LTNNMLMGITGMATAECMNMGIKMGLEPKVLLDVLNNSSARSWSTEVYCPVPGLVPTAPS 333
+ N +L G+ A +E M K GL+ + + +V+ S+ SW E P
Sbjct: 180 MINQLLAGVHIAAASEAMAFAAKQGLDIRKVYEVITASAGNSWMFENRMP-------HVL 232
Query: 332 SRNYDGGFKNELMVKDLELASGMALGIRSPIPLGAVAXQLYRIVQSRGYGQKDFSFVFQL 153
+Y E+ VKDL + MA R P+P+ A A Q++ + + G G+ D + V ++
Sbjct: 233 DGDYTPRSAVEIFVKDLGIIQDMARSARFPVPVSAAALQMFLMTAAAGMGRDDDASVARM 292
>UniRef50_A6VYD9 Cluster: 2-hydroxy-3-oxopropionate reductase
precursor; n=5; Gammaproteobacteria|Rep:
2-hydroxy-3-oxopropionate reductase precursor -
Marinomonas sp. MWYL1
Length = 300
Score = 74.1 bits (174), Expect = 4e-12
Identities = 49/174 (28%), Positives = 83/174 (47%), Gaps = 1/174 (0%)
Frame = -3
Query: 671 APVXGGVMGAQNVTXAFMAGGXKEDFERSLXLLKVMGXKQFHCG-QIGSGQVAKLTNNML 495
APV GG A MA G E FE+ +L K ++ G +IG G K+ + +L
Sbjct: 123 APVSGGAAKAATGDMTVMASGSVEAFEKLQPVLDATAAKVYNIGEEIGLGATVKIIHQLL 182
Query: 494 MGITGMATAECMNMGIKMGLEPKVLLDVLNNSSARSWSTEVYCPVPGLVPTAPSSRNYDG 315
G+ A AE M + + + ++ DV+ N++ SW E + +V +Y
Sbjct: 183 AGVHIAAGAEAMALAARANIPLDLMYDVVTNAAGNSWMFE--NRMKHVV-----DGDYSP 235
Query: 314 GFKNELMVKDLELASGMALGIRSPIPLGAVAXQLYRIVQSRGYGQKDFSFVFQL 153
++ VKDL L + A ++ P+PL + A ++ + G+GQ+D S V ++
Sbjct: 236 KSMVDIFVKDLNLVADTAKELKFPLPLSSTALNMFLSASNAGFGQEDDSAVIKI 289
>UniRef50_A3EW86 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=1;
Leptospirillum sp. Group II UBA|Rep:
3-hydroxyisobutyrate dehydrogenase - Leptospirillum sp.
Group II UBA
Length = 279
Score = 74.1 bits (174), Expect = 4e-12
Identities = 51/183 (27%), Positives = 85/183 (46%)
Frame = -3
Query: 692 KGLGFTXAPVXGGVMGAQNVTXAFMAGGXKEDFERSLXLLKVMGXKQFHCGQIGSGQVAK 513
KG G+ PV G ++ A+ +AGG ER+ +L G K H G GSG AK
Sbjct: 99 KGAGYLDVPVSGSLVPAEKGELLLLAGGDGAALERARPILLHFGKKILHFGPTGSGMKAK 158
Query: 512 LTNNMLMGITGMATAECMNMGIKMGLEPKVLLDVLNNSSARSWSTEVYCPVPGLVPTAPS 333
L N+L+ + + + +G +GL+ +L ++ +S + P +
Sbjct: 159 LVINLLLASHVESLVQTVLVGESLGLDGHQVLGMILDSPLAT-------PFYQIKRANLE 211
Query: 332 SRNYDGGFKNELMVKDLELASGMALGIRSPIPLGAVAXQLYRIVQSRGYGQKDFSFVFQL 153
R+YD F LM KDL+L S L R+P L + +R + G G++D S +++
Sbjct: 212 KRSYDKAFSARLMAKDLDLLSLTLLRNRTPASLPFELGRHFRELVESGRGEEDVSALYEY 271
Query: 152 LKE 144
++
Sbjct: 272 FRD 274
>UniRef50_Q0F1Y7 Cluster: 6-phosphogluconate dehydrogenase,
NAD-binding protein; n=1; Mariprofundus ferrooxydans
PV-1|Rep: 6-phosphogluconate dehydrogenase, NAD-binding
protein - Mariprofundus ferrooxydans PV-1
Length = 289
Score = 73.7 bits (173), Expect = 6e-12
Identities = 53/181 (29%), Positives = 79/181 (43%)
Frame = -3
Query: 689 GLGFTXAPVXGGVMGAQNVTXAFMAGGXKEDFERSLXLLKVMGXKQFHCGQIGSGQVAKL 510
G+ APV G + AQ T +AGG + LL MG K +CG GSG KL
Sbjct: 114 GMTLIDAPVSGSKVPAQTGTLVILAGGPEAAVRAQEPLLLSMGKKVIYCGPTGSGSAMKL 173
Query: 509 TNNMLMGITGMATAECMNMGIKMGLEPKVLLDVLNNSSARSWSTEVYCPVPGLVPTAPSS 330
N+L+GI AE +++ GL + LLD + S + C + L +
Sbjct: 174 AINLLLGIMTEGIAEALHLAESSGLASETLLDAVA-------SGPLSCTLFHLKEEMFKT 226
Query: 329 RNYDGGFKNELMVKDLELASGMALGIRSPIPLGAVAXQLYRIVQSRGYGQKDFSFVFQLL 150
NY F + M KD++ A + +PLG +L+ ++DF+ V LL
Sbjct: 227 GNYPPQFPFKHMAKDMQFVLAAAAENGAHLPLGTELAKLFSPAADADLQEQDFAAVKTLL 286
Query: 149 K 147
+
Sbjct: 287 E 287
>UniRef50_A4SWE8 Cluster: 2-hydroxy-3-oxopropionate reductase
precursor; n=7; Proteobacteria|Rep:
2-hydroxy-3-oxopropionate reductase precursor -
Polynucleobacter sp. QLW-P1DMWA-1
Length = 299
Score = 73.7 bits (173), Expect = 6e-12
Identities = 53/182 (29%), Positives = 82/182 (45%)
Frame = -3
Query: 689 GLGFTXAPVXGGVMGAQNVTXAFMAGGXKEDFERSLXLLKVMGXKQFHCGQIGSGQVAKL 510
G + APV GG +GA+ T M GG + F+ + +MG G G+GQV K+
Sbjct: 114 GCEYLDAPVSGGQVGAKGGTLTIMVGGKESVFQTVKPMFDLMGKNITLVGDNGAGQVTKV 173
Query: 509 TNNMLMGITGMATAECMNMGIKMGLEPKVLLDVLNNSSARSWSTEVYCPVPGLVPTAPSS 330
N +++ + A AE + K G +P + + L A S EV+
Sbjct: 174 ANQIIVALNIEAVAEALLFASKAGADPARVREALMGGFASSKILEVHA-------ERMIK 226
Query: 329 RNYDGGFKNELMVKDLELASGMALGIRSPIPLGAVAXQLYRIVQSRGYGQKDFSFVFQLL 150
R +D GF+ EL KDL LA A + +P A A +L+ + G D S + + L
Sbjct: 227 RTFDPGFRIELHQKDLNLALNSARALGVSLPNTANAQELFNSCLAYGGKAWDHSAMVKAL 286
Query: 149 KE 144
++
Sbjct: 287 EK 288
>UniRef50_Q9JYH6 Cluster: 3-hydroxyacid dehydrogenase; n=5;
Proteobacteria|Rep: 3-hydroxyacid dehydrogenase -
Neisseria meningitidis serogroup B
Length = 289
Score = 73.3 bits (172), Expect = 7e-12
Identities = 52/179 (29%), Positives = 79/179 (44%)
Frame = -3
Query: 680 FTXAPVXGGVMGAQNVTXAFMAGGXKEDFERSLXLLKVMGXKQFHCGQIGSGQVAKLTNN 501
F APV G V A N T + GG + + ++G K FH G +G G AKL N
Sbjct: 117 FAEAPVSGSVGPATNGTLLILFGGSEAVLNPLQKIFSLVGKKTFHFGDVGKGSGAKLVLN 176
Query: 500 MLMGITGMATAECMNMGIKMGLEPKVLLDVLNNSSARSWSTEVYCPVPGLVPTAPSSRNY 321
L+GI G A +E M M + G++ +++ + S+ S P+ + ++R +
Sbjct: 177 SLLGIFGEAYSEAMLMARQFGIDTDTIVEAIGGSAMDS-------PMFQTKKSLWANREF 229
Query: 320 DGGFKNELMVKDLELASGMALGIRSPIPLGAVAXQLYRIVQSRGYGQKDFSFVFQLLKE 144
F + KDL LA + +P YR GYG++D S V+ L E
Sbjct: 230 PPAFALKHASKDLNLAVKELEQAGNTLPAVETVAASYRKAVEAGYGEQDVSGVYLKLAE 288
>UniRef50_A4IN46 Cluster: 3-hydroxyisobutyrate dehydrogenase-like
protein; n=2; Geobacillus|Rep: 3-hydroxyisobutyrate
dehydrogenase-like protein - Geobacillus
thermodenitrificans (strain NG80-2)
Length = 304
Score = 73.3 bits (172), Expect = 7e-12
Identities = 53/184 (28%), Positives = 82/184 (44%)
Frame = -3
Query: 692 KGLGFTXAPVXGGVMGAQNVTXAFMAGGXKEDFERSLXLLKVMGXKQFHCGQIGSGQVAK 513
+G+ + APV GG GA+ T M GG + +ER LL V+G + G+ G+G AK
Sbjct: 112 RGVAYLDAPVSGGPEGAEQGTLTIMVGGDQAAWERVRPLLSVLGKTVEYLGESGAGSAAK 171
Query: 512 LTNNMLMGITGMATAECMNMGIKMGLEPKVLLDVLNNSSARSWSTEVYCPVPGLVPTAPS 333
+ N L+ + +A AE M G+ GL+ L +L S S + ++P
Sbjct: 172 ILNQYLVAVHSVAAAEAMVAGVAYGLDAGKLYRLLKESYGDSRMLRRHME-QFVLP---- 226
Query: 332 SRNYDGGFKNELMVKDLELASGMALGIRSPIPLGAVAXQLYRIVQSRGYGQKDFSFVFQL 153
R + G + + KD+ LA+ I LG A + + G D S V QL
Sbjct: 227 -RQFAPGGAVKYVHKDVRLANAFMNEIGINRCLGVEAEETFAAAMDAGLADLDMSAVIQL 285
Query: 152 LKEE 141
+ +
Sbjct: 286 FERQ 289
>UniRef50_Q7WCG3 Cluster: Putative uncharacterized protein; n=2;
Bordetella|Rep: Putative uncharacterized protein -
Bordetella parapertussis
Length = 296
Score = 72.9 bits (171), Expect = 1e-11
Identities = 37/104 (35%), Positives = 56/104 (53%)
Frame = -3
Query: 689 GLGFTXAPVXGGVMGAQNVTXAFMAGGXKEDFERSLXLLKVMGXKQFHCGQIGSGQVAKL 510
G APV GG++GA+ T M GG D E L++ MG + FHCG +GS ++AK+
Sbjct: 117 GARLVDAPVSGGIVGAEAGTLTIMMGGETADVEAVRPLMQAMGERLFHCGALGSAEIAKV 176
Query: 509 TNNMLMGITGMATAECMNMGIKMGLEPKVLLDVLNNSSARSWST 378
NNML TAE + + G+ + L +L+ S+ ++ T
Sbjct: 177 INNMLCVANMFLTAEAIELAESHGVAFESLTPILSVSTGLNFLT 220
>UniRef50_A1R2J4 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=1;
Arthrobacter aurescens TC1|Rep: 3-hydroxyisobutyrate
dehydrogenase - Arthrobacter aurescens (strain TC1)
Length = 332
Score = 72.9 bits (171), Expect = 1e-11
Identities = 57/174 (32%), Positives = 81/174 (46%), Gaps = 2/174 (1%)
Frame = -3
Query: 692 KGLGFTXAPVXGGVMGAQNVTXAFMAGGXKEDFERSLXLLKVMGXKQ--FHCGQIGSGQV 519
+G+ APV G +GA N GG D ER + + MG + H G G+G
Sbjct: 134 RGIRVLDAPVSGMSVGAANGMLQIFVGGEPADVERLRPVFEAMGDPERILHVGGHGAGYA 193
Query: 518 AKLTNNMLMGITGMATAECMNMGIKMGLEPKVLLDVLNNSSARSWSTEVYCPVPGLVPTA 339
KL N L +ATAE ++ G+K G++ +VL L S A S V V +
Sbjct: 194 VKLMINQLWFSHLVATAEVLSTGVKAGVDLEVLRQALIASPANSNF------VQNDVLSI 247
Query: 338 PSSRNYDGGFKNELMVKDLELASGMALGIRSPIPLGAVAXQLYRIVQSRGYGQK 177
+ +YD GF L KDL L+ +A + P+ L + QLYR ++ YG K
Sbjct: 248 LNHGDYDEGFAIALACKDLGLSVDLARSVGVPMELSGLVEQLYRRAKAL-YGDK 300
>UniRef50_P77161 Cluster: 2-hydroxy-3-oxopropionate reductase; n=99;
Proteobacteria|Rep: 2-hydroxy-3-oxopropionate reductase
- Escherichia coli (strain K12)
Length = 292
Score = 72.9 bits (171), Expect = 1e-11
Identities = 53/181 (29%), Positives = 80/181 (44%)
Frame = -3
Query: 689 GLGFTXAPVXGGVMGAQNVTXAFMAGGXKEDFERSLXLLKVMGXKQFHCGQIGSGQVAKL 510
G + APV GG +GA+ T + M GG + FER L +++G G G GQ K+
Sbjct: 111 GGDYLDAPVSGGEIGAREGTLSIMVGGDEAVFERVKPLFELLGKNITLVGGNGDGQTCKV 170
Query: 509 TNNMLMGITGMATAECMNMGIKMGLEPKVLLDVLNNSSARSWSTEVYCPVPGLVPTAPSS 330
N +++ + A +E + K G +P + L A S EV+
Sbjct: 171 ANQIIVALNIEAVSEALLFASKAGADPVRVRQALMGGFASSRILEVH-------GERMIK 223
Query: 329 RNYDGGFKNELMVKDLELASGMALGIRSPIPLGAVAXQLYRIVQSRGYGQKDFSFVFQLL 150
R ++ GFK L KDL LA A + +P A +L+ + G Q D S + Q L
Sbjct: 224 RTFNPGFKIALHQKDLNLALQSAKALALNLPNTATCQELFNTCAANGGSQLDHSALVQAL 283
Query: 149 K 147
+
Sbjct: 284 E 284
>UniRef50_Q1QWQ5 Cluster: 6-phosphogluconate dehydrogenase,
NAD-binding; n=4; Proteobacteria|Rep: 6-phosphogluconate
dehydrogenase, NAD-binding - Chromohalobacter salexigens
(strain DSM 3043 / ATCC BAA-138 / NCIMB13768)
Length = 315
Score = 72.5 bits (170), Expect = 1e-11
Identities = 51/185 (27%), Positives = 84/185 (45%)
Frame = -3
Query: 692 KGLGFTXAPVXGGVMGAQNVTXAFMAGGXKEDFERSLXLLKVMGXKQFHCGQIGSGQVAK 513
+G+G+ APV GG GA + T A M GG FER L +G + H G GSGQ+AK
Sbjct: 134 RGIGYLDAPVSGGERGAIDGTLAIMVGGDPATFERHRPLFAPLG-RAVHVGPAGSGQLAK 192
Query: 512 LTNNMLMGITGMATAECMNMGIKMGLEPKVLLDVLNNSSARSWSTEVYCPVPGLVPTAPS 333
L N ++ T AE + + + G +P+ + + L A S +V+
Sbjct: 193 LANQSIVANTIATVAEALLLAERGGADPRKVREALMGGFADSTILQVH-------GERML 245
Query: 332 SRNYDGGFKNELMVKDLELASGMALGIRSPIPLGAVAXQLYRIVQSRGYGQKDFSFVFQL 153
++ G + KD + A +A + +P+ + L+ + + G G D S + +
Sbjct: 246 DEDFRPGGPAKWQWKDTQTAQALADDLALDLPVSRLVDGLFGDLVANGDGDLDHSALIRE 305
Query: 152 LKEEN 138
L+ N
Sbjct: 306 LRRRN 310
>UniRef50_Q03UI4 Cluster: 3-hydroxyisobutyrate dehydrogenase related
enzyme; n=2; Lactobacillales|Rep: 3-hydroxyisobutyrate
dehydrogenase related enzyme - Leuconostoc mesenteroides
subsp. mesenteroides (strain ATCC 8293 /NCDO 523)
Length = 287
Score = 72.5 bits (170), Expect = 1e-11
Identities = 53/169 (31%), Positives = 82/169 (48%), Gaps = 3/169 (1%)
Frame = -3
Query: 686 LGFTX--APVXGGVMGAQNVTXAFMAGGXKEDFERSLXLLKVMGXKQFHCGQIGSGQVAK 513
LGF APV GG +GA+N T A M GG ++ + +L V+G + G G GQ K
Sbjct: 111 LGFKVLDAPVSGGDIGAKNGTLAIMVGGEQQVLDEIKPVLSVIGQQIVFAGSAGKGQHMK 170
Query: 512 LTNNMLMGITGMATAECMNMGIKMGLEPKVLLDVLNNSSARSWSTEVYCPVPGLVPTAPS 333
++NN+ + T + AE + GL+ + +V +A SWS + Y P
Sbjct: 171 MSNNIGVAATVITMAESLVYAKAAGLDLESAYNVWRKGAAGSWSVDNYIP-------RIF 223
Query: 332 SRNYDGGFKNELMVKDLELASGMALGIRSPIPLGAVAXQLY-RIVQSRG 189
+Y GF + ++KDL +A A + +P +A QL+ R+ Q G
Sbjct: 224 QGDYAPGFYVKHLLKDLRIALDAAKEMDIDLPNTKLAEQLFERLSQEHG 272
>UniRef50_A3SJ77 Cluster: Probable oxidoreductase; n=1; Roseovarius
nubinhibens ISM|Rep: Probable oxidoreductase -
Roseovarius nubinhibens ISM
Length = 320
Score = 72.1 bits (169), Expect = 2e-11
Identities = 52/182 (28%), Positives = 81/182 (44%)
Frame = -3
Query: 692 KGLGFTXAPVXGGVMGAQNVTXAFMAGGXKEDFERSLXLLKVMGXKQFHCGQIGSGQVAK 513
KGL APV AQN MAGG EDF + + + K H G GSG K
Sbjct: 122 KGLRVLDAPVGRTPKDAQNGALLIMAGGRAEDFADAAPVFAPLADKIVHLGPKGSGIRMK 181
Query: 512 LTNNMLMGITGMATAECMNMGIKMGLEPKVLLDVLNNSSARSWSTEVYCPVPGLVPTAPS 333
+ NN + ++ + TAE + M K G++ ++VL N++A V P L
Sbjct: 182 IANNYMSMVSMVLTAETLAMARKAGIDTDAAVEVLQNTTAGRGQINVNYPKKVL------ 235
Query: 332 SRNYDGGFKNELMVKDLELASGMALGIRSPIPLGAVAXQLYRIVQSRGYGQKDFSFVFQL 153
+ F + KD+ L G+ + P+ LGA A +L+ + S+ D + + L
Sbjct: 236 RGDISPDFPLAMGAKDISLGVGLGKSLGVPLFLGANAGELFNLAASQDIRDWDCTAMLVL 295
Query: 152 LK 147
++
Sbjct: 296 IE 297
>UniRef50_Q5L168 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=15;
Bacteria|Rep: 3-hydroxyisobutyrate dehydrogenase -
Geobacillus kaustophilus
Length = 288
Score = 71.7 bits (168), Expect = 2e-11
Identities = 49/169 (28%), Positives = 81/169 (47%)
Frame = -3
Query: 695 RKGLGFTXAPVXGGVMGAQNVTXAFMAGGXKEDFERSLXLLKVMGXKQFHCGQIGSGQVA 516
+KG+ APV GG +GA+ T M GG ++ F +L+ +G G G+GQ
Sbjct: 111 QKGIHALDAPVSGGDIGAREGTLTIMVGGDEDVFLACKPILERLGTNIVRQGGAGAGQHT 170
Query: 515 KLTNNMLMGITGMATAECMNMGIKMGLEPKVLLDVLNNSSARSWSTEVYCPVPGLVPTAP 336
K+ N + + + E M + GL+P +L+ + +A SWS + L P
Sbjct: 171 KMCNQIAIATNMIGVCEAMAYAKRAGLDPFKVLESIAKGAAGSWS------LSNLAPRML 224
Query: 335 SSRNYDGGFKNELMVKDLELASGMALGIRSPIPLGAVAXQLYRIVQSRG 189
S ++ GF + +KD+++A A + P+P A+A QLY + G
Sbjct: 225 SG-DFAPGFYVKHFIKDMKIALEEAERMNLPLPGLALAKQLYEELAQAG 272
>UniRef50_Q1IQE6 Cluster: 2-hydroxy-3-oxopropionate reductase
precursor; n=1; Acidobacteria bacterium Ellin345|Rep:
2-hydroxy-3-oxopropionate reductase precursor -
Acidobacteria bacterium (strain Ellin345)
Length = 282
Score = 71.3 bits (167), Expect = 3e-11
Identities = 45/182 (24%), Positives = 80/182 (43%)
Frame = -3
Query: 692 KGLGFTXAPVXGGVMGAQNVTXAFMAGGXKEDFERSLXLLKVMGXKQFHCGQIGSGQVAK 513
KG + AP+ G +GA++ FM G E ++ L MG K H G++G GQ +K
Sbjct: 106 KGADYIDAPITGSKIGAESAQLIFMVGAKDETLKKLEPLFLQMGKKIVHMGEVGKGQASK 165
Query: 512 LTNNMLMGITGMATAECMNMGIKMGLEPKVLLDVLNNSSARSWSTEVYCPVPGLVPTAPS 333
++ N+ + E + ++G+ P+ ++++ ++ RS + P
Sbjct: 166 ISLNLQIACIYEGFIEGFKVATQLGVNPEKFVELVQSTMVRSGVVDYKAPF-------VL 218
Query: 332 SRNYDGGFKNELMVKDLELASGMALGIRSPIPLGAVAXQLYRIVQSRGYGQKDFSFVFQL 153
R+Y F LM KDL L S A + +P ++Y G +D++ L
Sbjct: 219 KRDYTPNFPLRLMRKDLLLVSDAAKQLELDLPGLKSVLEVYDEAHEAGMDDQDYAATLAL 278
Query: 152 LK 147
L+
Sbjct: 279 LE 280
>UniRef50_Q8EW87 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=1;
Mycoplasma penetrans|Rep: 3-hydroxyisobutyrate
dehydrogenase - Mycoplasma penetrans
Length = 288
Score = 70.9 bits (166), Expect = 4e-11
Identities = 37/103 (35%), Positives = 56/103 (54%)
Frame = -3
Query: 692 KGLGFTXAPVXGGVMGAQNVTXAFMAGGXKEDFERSLXLLKVMGXKQFHCGQIGSGQVAK 513
KG+ APV GG +GA N T + M GG E F++ +LK++G K + G G GQ AK
Sbjct: 110 KGIKVLDAPVTGGDIGALNGTLSIMVGGDFETFKKVESILKILGNKINYFGSAGKGQHAK 169
Query: 512 LTNNMLMGITGMATAECMNMGIKMGLEPKVLLDVLNNSSARSW 384
L N +L+ + ATAE +N K ++ + V + + +W
Sbjct: 170 LFNQILVAVNTFATAEVLNYCKKNNVDIEAAYKVFDKTIGNNW 212
>UniRef50_A2SP40 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=1;
Methylibium petroleiphilum PM1|Rep: 3-hydroxyisobutyrate
dehydrogenase - Methylibium petroleiphilum (strain PM1)
Length = 297
Score = 70.9 bits (166), Expect = 4e-11
Identities = 50/155 (32%), Positives = 75/155 (48%), Gaps = 1/155 (0%)
Frame = -3
Query: 623 FMAGGXKEDFERSLXLLKVMGXKQFHCGQIGSGQVAKLTNNML-MGITGMATAECMNMGI 447
F GG E ++ L LL+V+ K G IG+ + KL NN++ +G +A AE +G+
Sbjct: 135 FQVGGPDELIDQHLELLQVLAKKINRTGGIGTAKTVKLVNNLMSLGNVAVA-AEAFVLGV 193
Query: 446 KMGLEPKVLLDVLNNSSARSWSTEVYCPVPGLVPTAPSSRNYDGGFKNELMVKDLELASG 267
K G+EPK L ++L+ S RS + G +Y FK L +KD+ L
Sbjct: 194 KCGMEPKRLYEILSVSGGRSAHF-----ISGFQKVIEG--DYGASFKTSLALKDINLILD 246
Query: 266 MALGIRSPIPLGAVAXQLYRIVQSRGYGQKDFSFV 162
+A L V LYR RG G+++F+ V
Sbjct: 247 LANEEHYAARLAPVIASLYRDAVGRGLGEENFTSV 281
>UniRef50_Q73P00 Cluster: 3-hydroxyacid dehydrogenase family
protein; n=4; Bacteria|Rep: 3-hydroxyacid dehydrogenase
family protein - Treponema denticola
Length = 292
Score = 70.5 bits (165), Expect = 5e-11
Identities = 45/175 (25%), Positives = 80/175 (45%)
Frame = -3
Query: 671 APVXGGVMGAQNVTXAFMAGGXKEDFERSLXLLKVMGXKQFHCGQIGSGQVAKLTNNMLM 492
APV GG +GA+N T + MAGG + F+ MG G G+GQ K+ N + +
Sbjct: 123 APVSGGDIGAKNGTLSIMAGGDESAFKELEPFFACMGKTWALQGGAGAGQHTKMANQIAV 182
Query: 491 GITGMATAECMNMGIKMGLEPKVLLDVLNNSSARSWSTEVYCPVPGLVPTAPSSRNYDGG 312
T E + GL+P +L + +A SW ++ P ++ +++ G
Sbjct: 183 AANLFGTVEAVCYAEAAGLDPHKMLSAIGGGAAGSW--QILNNGPKML-----QKDFAPG 235
Query: 311 FKNELMVKDLELASGMALGIRSPIPLGAVAXQLYRIVQSRGYGQKDFSFVFQLLK 147
F + +KDL + +A ++ IP+ +A + + GY +K +++ K
Sbjct: 236 FYIKHFLKDLNITLNVAKELKLHIPVLELAQNFFNKMNEEGYAEKGTQAIYEYYK 290
>UniRef50_Q9LM23 Cluster: Fructose-bisphosphate aldolase; n=2;
Arabidopsis thaliana|Rep: Fructose-bisphosphate aldolase
- Arabidopsis thaliana (Mouse-ear cress)
Length = 1486
Score = 70.5 bits (165), Expect = 5e-11
Identities = 50/174 (28%), Positives = 80/174 (45%), Gaps = 1/174 (0%)
Frame = -3
Query: 692 KGLGFTXAPVXGGVMGAQNVTXAFMAGGXKEDFERSLXLLKVMGXKQFHC-GQIGSGQVA 516
K L APV GGV A MA G E + + +L + K + G G+G
Sbjct: 467 KDLKLVDAPVSGGVKRAAMGELTIMASGTDEALKSAGLVLSALSEKLYVIKGGCGAGSGV 526
Query: 515 KLTNNMLMGITGMATAECMNMGIKMGLEPKVLLDVLNNSSARSWSTEVYCPVPGLVPTAP 336
K+ N +L G+ + AE M G ++GL + L +V++NS SW E VP ++
Sbjct: 527 KMVNQLLAGVHIASAAEAMAFGARLGLNTRKLFNVISNSGGTSWMFE--NRVPHML---- 580
Query: 335 SSRNYDGGFKNELMVKDLELASGMALGIRSPIPLGAVAXQLYRIVQSRGYGQKD 174
+Y ++ VKDL + + + P+ + VA QL+ + G+G+ D
Sbjct: 581 -DNDYTPYSALDIFVKDLGIVTREGSSRKVPLHISTVAHQLFLAGSAAGWGRID 633
Score = 56.8 bits (131), Expect = 7e-07
Identities = 37/136 (27%), Positives = 71/136 (52%), Gaps = 1/136 (0%)
Frame = -3
Query: 620 MAGGXKEDFERSLXLLKVMGXKQFHC-GQIGSGQVAKLTNNMLMGITGMATAECMNMGIK 444
+A G + R+ L M + G+IG+G K+ N +L GI +A E +++G +
Sbjct: 163 IASGRSDSITRAQPYLTAMCQNLYTFEGEIGAGSKVKMVNELLEGIHLVAAVEAISLGSQ 222
Query: 443 MGLEPKVLLDVLNNSSARSWSTEVYCPVPGLVPTAPSSRNYDGGFKNELMVKDLELASGM 264
G+ P +L D+++N++ SW + + P+ L+ + +G F +++ ++L +
Sbjct: 223 AGVHPWILYDIISNAAGNSWIYKNHIPL--LL-----KDDIEGRFL-DVLSQNLAIVEDK 274
Query: 263 ALGIRSPIPLGAVAXQ 216
A + P+PL AVA Q
Sbjct: 275 AKSLPFPVPLLAVARQ 290
>UniRef50_Q8VYC5 Cluster: Fructose-bisphosphate aldolase; n=12;
cellular organisms|Rep: Fructose-bisphosphate aldolase -
Arabidopsis thaliana (Mouse-ear cress)
Length = 1373
Score = 70.5 bits (165), Expect = 5e-11
Identities = 50/174 (28%), Positives = 80/174 (45%), Gaps = 1/174 (0%)
Frame = -3
Query: 692 KGLGFTXAPVXGGVMGAQNVTXAFMAGGXKEDFERSLXLLKVMGXKQFHC-GQIGSGQVA 516
K L APV GGV A MA G E + + +L + K + G G+G
Sbjct: 434 KDLKLVDAPVSGGVKRAAMGELTIMASGTDEALKSAGLVLSALSEKLYVIKGGCGAGSGV 493
Query: 515 KLTNNMLMGITGMATAECMNMGIKMGLEPKVLLDVLNNSSARSWSTEVYCPVPGLVPTAP 336
K+ N +L G+ + AE M G ++GL + L +V++NS SW E VP ++
Sbjct: 494 KMVNQLLAGVHIASAAEAMAFGARLGLNTRKLFNVISNSGGTSWMFE--NRVPHML---- 547
Query: 335 SSRNYDGGFKNELMVKDLELASGMALGIRSPIPLGAVAXQLYRIVQSRGYGQKD 174
+Y ++ VKDL + + + P+ + VA QL+ + G+G+ D
Sbjct: 548 -DNDYTPYSALDIFVKDLGIVTREGSSRKVPLHISTVAHQLFLAGSAAGWGRID 600
Score = 56.8 bits (131), Expect = 7e-07
Identities = 37/136 (27%), Positives = 71/136 (52%), Gaps = 1/136 (0%)
Frame = -3
Query: 620 MAGGXKEDFERSLXLLKVMGXKQFHC-GQIGSGQVAKLTNNMLMGITGMATAECMNMGIK 444
+A G + R+ L M + G+IG+G K+ N +L GI +A E +++G +
Sbjct: 139 IASGRSDSITRAQPYLTAMCQNLYTFEGEIGAGSKVKMVNELLEGIHLVAAVEAISLGSQ 198
Query: 443 MGLEPKVLLDVLNNSSARSWSTEVYCPVPGLVPTAPSSRNYDGGFKNELMVKDLELASGM 264
G+ P +L D+++N++ SW + + P+ L+ + +G F +++ ++L +
Sbjct: 199 AGVHPWILYDIISNAAGNSWIYKNHIPL--LL-----KDDIEGRFL-DVLSQNLAIVEDK 250
Query: 263 ALGIRSPIPLGAVAXQ 216
A + P+PL AVA Q
Sbjct: 251 AKSLPFPVPLLAVARQ 266
>UniRef50_Q7WNK6 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=1;
Bordetella bronchiseptica|Rep: 3-hydroxyisobutyrate
dehydrogenase - Bordetella bronchiseptica (Alcaligenes
bronchisepticus)
Length = 306
Score = 70.1 bits (164), Expect = 7e-11
Identities = 48/180 (26%), Positives = 78/180 (43%), Gaps = 1/180 (0%)
Frame = -3
Query: 689 GLGFTXAPVXGGVMGAQNVTXAFMAGGXKEDFERSLXLLKVMGXKQFHCGQ-IGSGQVAK 513
G G PV GG GAQ +A G + + ++ G+ G+ K
Sbjct: 118 GAGLVDGPVSGGATGAQAGALTIIASGQAQALAAAEPAMRACSSIIHRVGEEAGAASTVK 177
Query: 512 LTNNMLMGITGMATAECMNMGIKMGLEPKVLLDVLNNSSARSWSTEVYCPVPGLVPTAPS 333
L N +L TAE + +G + G++P VL+ V++ S+ S E P AP
Sbjct: 178 LVNQLLTASHIALTAEALALGARAGVDPDVLVKVISQSAGTSRQFEKRAPRMAAGDHAPQ 237
Query: 332 SRNYDGGFKNELMVKDLELASGMALGIRSPIPLGAVAXQLYRIVQSRGYGQKDFSFVFQL 153
S ++ +KDLE+A A +R P+P+ A A Q++ + G G + V ++
Sbjct: 238 STV-------DIFLKDLEIALDAARALRFPVPIAASAHQVFSMAAGAGDGPNSDTTVLRV 290
>UniRef50_Q7NEW9 Cluster: Glr3759 protein; n=3; Bacteria|Rep:
Glr3759 protein - Gloeobacter violaceus
Length = 290
Score = 70.1 bits (164), Expect = 7e-11
Identities = 51/180 (28%), Positives = 78/180 (43%)
Frame = -3
Query: 692 KGLGFTXAPVXGGVMGAQNVTXAFMAGGXKEDFERSLXLLKVMGXKQFHCGQIGSGQVAK 513
+G APV G A+ F+ GG ++ +L MG H G +G+G K
Sbjct: 113 RGKTLLDAPVSGSRPQAEAGQLIFLVGGDAGAVAKAGPILNAMGGTVHHAGPLGNGAAVK 172
Query: 512 LTNNMLMGITGMATAECMNMGIKMGLEPKVLLDVLNNSSARSWSTEVYCPVPGLVPTAPS 333
L N L+G+ A E + + G++ ++++ ST V P +A +
Sbjct: 173 LAINALLGVQVAAMGELIALLRHCGIDEVRAVEIIG-------STSVCSPAARGAASAMA 225
Query: 332 SRNYDGGFKNELMVKDLELASGMALGIRSPIPLGAVAXQLYRIVQSRGYGQKDFSFVFQL 153
NY F + LM KDL MA R+ PL A ++ SRGYG+ + + V QL
Sbjct: 226 VGNYAPLFPSALMEKDLGYLQNMAAAHRARAPLTQAARSVFGEAMSRGYGEDNMTGVAQL 285
>UniRef50_A0QZR7 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=1;
Mycobacterium smegmatis str. MC2 155|Rep:
3-hydroxyisobutyrate dehydrogenase - Mycobacterium
smegmatis (strain ATCC 700084 / mc(2)155)
Length = 299
Score = 70.1 bits (164), Expect = 7e-11
Identities = 52/173 (30%), Positives = 77/173 (44%), Gaps = 1/173 (0%)
Frame = -3
Query: 689 GLGFTXAPVXGGVMGAQNVTXAFMAGGXKEDFERSLXLLKVMGXKQFHCG-QIGSGQVAK 513
G G APV GG GA+ + MA G E+ + V+ K G Q G Q K
Sbjct: 113 GYGCLDAPVSGGAEGARTGSLTIMASGDPTTIEQCSSVFDVIAGKVIVVGNQPGQAQAIK 172
Query: 512 LTNNMLMGITGMATAECMNMGIKMGLEPKVLLDVLNNSSARSWSTEVYCPVPGLVPTAPS 333
+ NN+L +ATAE + K G+ L+ LN SS R+ +T V P L
Sbjct: 173 VANNVLSLGALVATAEATAITRKAGIPLDTALEALNASSGRNTATAVKFPRHVL------ 226
Query: 332 SRNYDGGFKNELMVKDLELASGMALGIRSPIPLGAVAXQLYRIVQSRGYGQKD 174
+ +D GF +KD+ L +A + PL + ++ +G+GQ+D
Sbjct: 227 TGRFDFGFPTSGALKDVSLFLELAAELGVEAPLSSAVQAIWHTAAEQGFGQQD 279
>UniRef50_A6SUL3 Cluster: 2-hydroxy-3-oxopropionate reductase; n=1;
Janthinobacterium sp. Marseille|Rep:
2-hydroxy-3-oxopropionate reductase - Janthinobacterium
sp. (strain Marseille) (Minibacterium massiliensis)
Length = 304
Score = 69.7 bits (163), Expect = 9e-11
Identities = 58/187 (31%), Positives = 88/187 (47%), Gaps = 2/187 (1%)
Frame = -3
Query: 692 KGLGFTXAPVXGGVMGAQNVTXAFMAGGXKEDFERSLXLLKVMGXKQFHCGQIGSGQVAK 513
+G+ F APV GGV+GA+ + A MAGG +DF + +L VMG G G GQ+AK
Sbjct: 115 QGVRFIDAPVSGGVVGAEAGSLAIMAGGSAQDFAEAEAVLTVMGRPTL-VGPAGCGQIAK 173
Query: 512 LTNNMLMGITGMATAECMNMGIKMGLEPKVLLDVLNNSSARSWSTEVYCPVPGLVPTAPS 333
L N +++G T AE + + G +P + + A S EV+
Sbjct: 174 LCNQLIVGGTLNIVAEALLLAQAGGADPTAVRAAIRGGFAESRILEVH-------GQRML 226
Query: 332 SRNYDGGFKNELMVKDLE--LASGMALGIRSPIPLGAVAXQLYRIVQSRGYGQKDFSFVF 159
RN+ G + + KDLE L + G+R P+ V ++++Q+ Q D S V
Sbjct: 227 DRNFMPGGQVKSQFKDLENVLIAANNAGLRLPV-TELVTENYHQVLQNA--PQADQSAVL 283
Query: 158 QLLKEEN 138
L+ N
Sbjct: 284 LALEAGN 290
>UniRef50_Q7Q161 Cluster: ENSANGP00000013149; n=11; Culicidae|Rep:
ENSANGP00000013149 - Anopheles gambiae str. PEST
Length = 581
Score = 69.3 bits (162), Expect = 1e-10
Identities = 49/180 (27%), Positives = 82/180 (45%), Gaps = 2/180 (1%)
Frame = -3
Query: 692 KGLGFTXAPVXGGVMGAQNVTXAFMAGGXKEDFERSLXLLKVMGXKQFHCGQIGSGQVAK 513
KG + A + G A+ T +A G + FE + + F+ G +G+
Sbjct: 406 KGGRYLEAQIQGSKNQAEEGTLIILASGDRLLFEECQSCFEAISRNSFYLGDVGNATKMN 465
Query: 512 LTNNMLMGITGMATAECMNMGIKMGLEPKVLLDV--LNNSSARSWSTEVYCPVPGLVPTA 339
L M+ GIT AE M + + GL+ K +L+V L N S+ + + G PT
Sbjct: 466 LILQMISGITLAGVAEAMALADRAGLQQKDVLEVLELTNMSSEMMLQKGNAIIKGEFPTH 525
Query: 338 PSSRNYDGGFKNELMVKDLELASGMALGIRSPIPLGAVAXQLYRIVQSRGYGQKDFSFVF 159
+ ++ M KDL+LA +A G+ +P+ A + ++Y+ + GYG D S V+
Sbjct: 526 HALKH---------MQKDLKLALSLADGLEQSLPITAASNEVYKHAKRLGYGSHDASAVY 576
>UniRef50_A2C1U6 Cluster: 3-hydroxyisobutyrate dehydrogenase and
related beta-hydroxyacid dehydrogenases; n=2;
Prochlorococcus marinus|Rep: 3-hydroxyisobutyrate
dehydrogenase and related beta-hydroxyacid
dehydrogenases - Prochlorococcus marinus (strain NATL1A)
Length = 287
Score = 68.9 bits (161), Expect = 2e-10
Identities = 48/183 (26%), Positives = 81/183 (44%)
Frame = -3
Query: 680 FTXAPVXGGVMGAQNVTXAFMAGGXKEDFERSLXLLKVMGXKQFHCGQIGSGQVAKLTNN 501
+ PV GG GA N + + G ++D + +V+G + +G GQ K N
Sbjct: 111 YVDCPVSGGTEGAHNGSLSLFIGASEKDCLSFENIFQVLGKSINYFNGVGKGQQVKALNQ 170
Query: 500 MLMGITGMATAECMNMGIKMGLEPKVLLDVLNNSSARSWSTEVYCPVPGLVPTAPSSRNY 321
+L+ T A AE M +G + L ++ L +A SW E L+ P
Sbjct: 171 ILVAGTYAAVAEAMELGKMLELPMDDVVAALKVGAANSWPLENRSKAM-LIDKHPL---- 225
Query: 320 DGGFKNELMVKDLELASGMALGIRSPIPLGAVAXQLYRIVQSRGYGQKDFSFVFQLLKEE 141
GFK EL KDL +A+ +A I +P+ + ++ + + G G+ D S + + + +
Sbjct: 226 --GFKLELHHKDLSIATELAKSINIDLPIASKVKEMEQRLMQTGLGELDVSVLHRYISNK 283
Query: 140 NXN 132
N
Sbjct: 284 RIN 286
>UniRef50_A0G5G5 Cluster: 6-phosphogluconate dehydrogenase,
NAD-binding; n=3; Proteobacteria|Rep: 6-phosphogluconate
dehydrogenase, NAD-binding - Burkholderia phymatum
STM815
Length = 306
Score = 68.9 bits (161), Expect = 2e-10
Identities = 52/173 (30%), Positives = 78/173 (45%), Gaps = 2/173 (1%)
Frame = -3
Query: 695 RKGLGFTXAPVXGGVMGAQNVTXAFMAGGXKEDFERSLXLLKVMGXKQFHCGQIGSGQVA 516
+ G+ + A + GG A+ M GG + + K H G+ G+G
Sbjct: 110 QSGVQYVDAGISGGAAAAEKGALTLMVGGDASAVDALKWAFAPISSKVAHMGESGAGHTT 169
Query: 515 KLTNNMLMGITGMATAECMNMGIKMGLEPKVLLDVLNNSSARSWSTEVYCPVPGLVPTAP 336
KL NN L ++ A+AE M G K GL+ +LLDVLN+SS +++T P
Sbjct: 170 KLLNNFLNAVSLSASAEVMVAGKKAGLDLHLLLDVLNSSSGVNFAT------LNRFPKIV 223
Query: 335 SSRNYDGGFKNELMVKDLELASGMA--LGIRSPIPLGAVAXQLYRIVQSRGYG 183
+GG +LM KD+ L A LG+ S G +A + + + GYG
Sbjct: 224 DGDYLEGGLTGKLMTKDVVLYVDRARELGVVSLNAAGPLAS--FGLGTALGYG 274
>UniRef50_A7PEG7 Cluster: Chromosome chr11 scaffold_13, whole genome
shotgun sequence; n=2; Vitis vinifera|Rep: Chromosome
chr11 scaffold_13, whole genome shotgun sequence - Vitis
vinifera (Grape)
Length = 348
Score = 68.9 bits (161), Expect = 2e-10
Identities = 52/170 (30%), Positives = 80/170 (47%)
Frame = -3
Query: 692 KGLGFTXAPVXGGVMGAQNVTXAFMAGGXKEDFERSLXLLKVMGXKQFHCGQIGSGQVAK 513
+G APV GG GA+N T A AGG + R L +G K + G G GQ AK
Sbjct: 160 RGCFSVDAPVSGGDRGAKNATLAIFAGGDESVVRRLNPLFSHLG-KVNYMGGPGKGQYAK 218
Query: 512 LTNNMLMGITGMATAECMNMGIKMGLEPKVLLDVLNNSSARSWSTEVYCPVPGLVPTAPS 333
L N +++ T + E M K GL+ + L+ ++ +A S S ++Y +
Sbjct: 219 LANQIIIASTMLGLIEGMMYAYKSGLDVALFLNAISTGAAGSKSLDLY-------GSRIL 271
Query: 332 SRNYDGGFKNELMVKDLELASGMALGIRSPIPLGAVAXQLYRIVQSRGYG 183
R+++ GF VKDL + + +P A+A QLY +++ G G
Sbjct: 272 KRDFEAGFFVNHFVKDLGICLIECQKMGLSLPGLALAQQLYLSLKAHGEG 321
>UniRef50_A7IE35 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=2;
Proteobacteria|Rep: 3-hydroxyisobutyrate dehydrogenase -
Xanthobacter sp. (strain Py2)
Length = 330
Score = 68.5 bits (160), Expect = 2e-10
Identities = 46/177 (25%), Positives = 78/177 (44%), Gaps = 1/177 (0%)
Frame = -3
Query: 680 FTXAPVXGGVMGAQNVTXAFMAGGXKEDFERSLXLLKVMGXKQFHCGQI-GSGQVAKLTN 504
+ AP+ GG A +A G F ++ L M K + G G G K+ N
Sbjct: 147 YLDAPISGGAQRAAEGALTILASGSPAAFAKARPALDAMAAKLYELGDAPGQGAAFKMIN 206
Query: 503 NMLMGITGMATAECMNMGIKMGLEPKVLLDVLNNSSARSWSTEVYCPVPGLVPTAPSSRN 324
+L G+ A +E + + GL+ + +V+ S+ SW E +P +V +
Sbjct: 207 QLLAGVHIAAASEAVAFAARQGLDIAKVYEVITASAGNSWMFENR--MPHVV-----DGD 259
Query: 323 YDGGFKNELMVKDLELASGMALGIRSPIPLGAVAXQLYRIVQSRGYGQKDFSFVFQL 153
Y ++ VKDL + MA + P+P+ A A Q++ + G G+ D + V +L
Sbjct: 260 YTPRSAVDIFVKDLGIIQDMARSAKFPVPVSAAALQMFLATSAAGMGRDDDASVARL 316
>UniRef50_Q9RX16 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=6;
Bacteria|Rep: 3-hydroxyisobutyrate dehydrogenase -
Deinococcus radiodurans
Length = 310
Score = 68.1 bits (159), Expect = 3e-10
Identities = 52/184 (28%), Positives = 82/184 (44%)
Frame = -3
Query: 689 GLGFTXAPVXGGVMGAQNVTXAFMAGGXKEDFERSLXLLKVMGXKQFHCGQIGSGQVAKL 510
G+ F APV GG GA+ T M GG ++ + + L G K G+ G+G K
Sbjct: 129 GVKFLDAPVSGGTSGAEAGTLTVMLGGPADEIDAASPHLAFAG-KVVRVGETGAGFAVKA 187
Query: 509 TNNMLMGITGMATAECMNMGIKMGLEPKVLLDVLNNSSARSWSTEVYCPVPGLVPTAPSS 330
NNML+ + A E + + G++ L V+N SS RS ++E L+P +
Sbjct: 188 VNNMLLAVNLWAAGEGLAALGRSGVDLGAALSVINASSGRSNASE------NLIPQRVLT 241
Query: 329 RNYDGGFKNELMVKDLELASGMALGIRSPIPLGAVAXQLYRIVQSRGYGQKDFSFVFQLL 150
R + F L+ KD +A + ++ P A L R Q+D + +LL
Sbjct: 242 REFPVTFALGLLAKDTGIALDVVQSAKASAPTLAQVAGLIRAAAHVVGPQEDHTAALKLL 301
Query: 149 KEEN 138
++ N
Sbjct: 302 EQMN 305
>UniRef50_Q0BTJ3 Cluster: 2-hydroxy-3-oxopropionate reductase; n=1;
Granulibacter bethesdensis CGDNIH1|Rep:
2-hydroxy-3-oxopropionate reductase - Granulobacter
bethesdensis (strain ATCC BAA-1260 / CGDNIH1)
Length = 293
Score = 68.1 bits (159), Expect = 3e-10
Identities = 49/181 (27%), Positives = 81/181 (44%)
Frame = -3
Query: 680 FTXAPVXGGVMGAQNVTXAFMAGGXKEDFERSLXLLKVMGXKQFHCGQIGSGQVAKLTNN 501
+ APV GG GA+N T A MAGG + R + +G + G IG+GQ+AKL N
Sbjct: 114 YVDAPVSGGEGGARNGTLAIMAGGEEAVLNRLAPVFAALG-RMTRIGDIGAGQLAKLANQ 172
Query: 500 MLMGITGMATAECMNMGIKMGLEPKVLLDVLNNSSARSWSTEVYCPVPGLVPTAPSSRNY 321
+++G+T A +E + G P D + A S + N+
Sbjct: 173 LIVGVTIGAVSEAFVLAEAGGASPARFRDAVAGGFADSRILREH-------GQRMLDENF 225
Query: 320 DGGFKNELMVKDLELASGMALGIRSPIPLGAVAXQLYRIVQSRGYGQKDFSFVFQLLKEE 141
G K+ + +KDL + A + +P+ A LYR + G G D + + + ++ +
Sbjct: 226 VPGGKSAIQLKDLRMILQEAKMLGLSLPMTEAAAALYRALCEAGDGDLDHAGLIRQIRRD 285
Query: 140 N 138
+
Sbjct: 286 S 286
>UniRef50_A6G049 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=1;
Plesiocystis pacifica SIR-1|Rep: 3-hydroxyisobutyrate
dehydrogenase - Plesiocystis pacifica SIR-1
Length = 307
Score = 68.1 bits (159), Expect = 3e-10
Identities = 49/183 (26%), Positives = 82/183 (44%), Gaps = 1/183 (0%)
Frame = -3
Query: 692 KGLGFTXAPVXGGVMGAQNVTXAFMAGGXKEDFERSLXLLKVMGXKQFHCGQ-IGSGQVA 516
+G F AP+ G +GA+ M G +E R++ L ++MG H + +G GQ A
Sbjct: 123 EGASFLDAPITGSKLGAEGGKLTIMVAGEEEIVARAMPLFEIMGKHTVHVSERLGDGQRA 182
Query: 515 KLTNNMLMGITGMATAECMNMGIKMGLEPKVLLDVLNNSSARSWSTEVYCPVPGLVPTAP 336
K NM + E + + + + ++L NS+ ++ P L+
Sbjct: 183 KYCLNMTQAVVLQGLLEGYTLAKLLDVPLTKMAEILENSAGKTGLGTFKTPY--LL---- 236
Query: 335 SSRNYDGGFKNELMVKDLELASGMALGIRSPIPLGAVAXQLYRIVQSRGYGQKDFSFVFQ 156
+ +++ F+ +LM KDL LA A R P+P V LY + G G +DF +
Sbjct: 237 -AGDFEPHFRLDLMHKDLHLALRHAENERVPLPAATVVRGLYDQAVAEGMGPRDFLAMAT 295
Query: 155 LLK 147
LL+
Sbjct: 296 LLE 298
>UniRef50_O33730 Cluster: Uncharacterized oxidoreductase Sfri_1503;
n=167; Bacteria|Rep: Uncharacterized oxidoreductase
Sfri_1503 - Shewanella frigidimarina (strain NCIMB 400)
Length = 291
Score = 68.1 bits (159), Expect = 3e-10
Identities = 49/181 (27%), Positives = 82/181 (45%)
Frame = -3
Query: 686 LGFTXAPVXGGVMGAQNVTXAFMAGGXKEDFERSLXLLKVMGXKQFHCGQIGSGQVAKLT 507
+ F APV GG GA+N M GG + F+ ++ G +G+GQ+ K+
Sbjct: 115 IAFLDAPVSGGQAGAENGALTVMMGGDQAHFDTVKPVISAYSRCAELLGPVGAGQLTKMV 174
Query: 506 NNMLMGITGMATAECMNMGIKMGLEPKVLLDVLNNSSARSWSTEVYCPVPGLVPTAPSSR 327
N + + AE ++ GL+ +++V++ +A+SW E T +
Sbjct: 175 NQICIAGVVQGLAEGLHFAKSAGLDGLKVIEVISKGAAQSWQME------NRYKTMWQGQ 228
Query: 326 NYDGGFKNELMVKDLELASGMALGIRSPIPLGAVAXQLYRIVQSRGYGQKDFSFVFQLLK 147
YD GF + M KDL +A A S +P+ A+ Q Y VQ+ + D S + L+
Sbjct: 229 -YDFGFAIDWMRKDLGIALDEARRNGSHLPVAALVDQFYSEVQAMKGNRWDTSSLLARLE 287
Query: 146 E 144
+
Sbjct: 288 K 288
>UniRef50_A6LT11 Cluster: 6-phosphogluconate dehydrogenase,
NAD-binding; n=3; Clostridiales|Rep: 6-phosphogluconate
dehydrogenase, NAD-binding - Clostridium beijerinckii
NCIMB 8052
Length = 291
Score = 67.7 bits (158), Expect = 4e-10
Identities = 39/133 (29%), Positives = 65/133 (48%)
Frame = -3
Query: 671 APVXGGVMGAQNVTXAFMAGGXKEDFERSLXLLKVMGXKQFHCGQIGSGQVAKLTNNMLM 492
APV GG +GA+N T + M GG E FE+ +L +G + G+ G+GQ K+ N + +
Sbjct: 119 APVSGGDVGAKNATLSIMVGGDLEVFEKHKDVLSALGTNIIYEGKAGNGQHTKMANQIAL 178
Query: 491 GITGMATAECMNMGIKMGLEPKVLLDVLNNSSARSWSTEVYCPVPGLVPTAPSSRNYDGG 312
E + +GL+ + +LD ++ +A SW + P ++D G
Sbjct: 179 AGAIAGVCEAITYAKGVGLDVQTMLDSISEGAAGSWQMKNMAP-------RMLKGDFDPG 231
Query: 311 FKNELMVKDLELA 273
F + +KD+ LA
Sbjct: 232 FYIKHFIKDMNLA 244
>UniRef50_A5USN9 Cluster: 6-phosphogluconate dehydrogenase,
NAD-binding; n=2; Roseiflexus|Rep: 6-phosphogluconate
dehydrogenase, NAD-binding - Roseiflexus sp. RS-1
Length = 302
Score = 67.7 bits (158), Expect = 4e-10
Identities = 50/184 (27%), Positives = 81/184 (44%)
Frame = -3
Query: 695 RKGLGFTXAPVXGGVMGAQNVTXAFMAGGXKEDFERSLXLLKVMGXKQFHCGQIGSGQVA 516
++G APV G V A+ + GG D ER+ L V+G + H G G+G
Sbjct: 111 QRGARLLDAPVSGTVAPAREGQLLVLVGGRTSDLERARPALGVLGRRIIHLGGQGAGTTM 170
Query: 515 KLTNNMLMGITGMATAECMNMGIKMGLEPKVLLDVLNNSSARSWSTEVYCPVPGLVPTAP 336
KL NM M A AE + +G + GL + +LDV +S+ + P L+
Sbjct: 171 KLVLNMTMACFWGALAESLAVGQQFGLNIETMLDVYLDSAVA--PPALRSKTPALLGETS 228
Query: 335 SSRNYDGGFKNELMVKDLELASGMALGIRSPIPLGAVAXQLYRIVQSRGYGQKDFSFVFQ 156
G + +L+ +A+ G+ P P+ + A + + GYG++D + V +
Sbjct: 229 EVAFDVTGVRKDLLAM---VATAQDAGV--PAPVASAALAHFAAATAAGYGERDLAAVVE 283
Query: 155 LLKE 144
L E
Sbjct: 284 YLAE 287
>UniRef50_Q0FFH2 Cluster: Putative 2-hydroxyacid dehydrogenase; n=2;
Alphaproteobacteria|Rep: Putative 2-hydroxyacid
dehydrogenase - alpha proteobacterium HTCC2255
Length = 303
Score = 66.9 bits (156), Expect = 6e-10
Identities = 44/132 (33%), Positives = 62/132 (46%)
Frame = -3
Query: 671 APVXGGVMGAQNVTXAFMAGGXKEDFERSLXLLKVMGXKQFHCGQIGSGQVAKLTNNMLM 492
APV G V GA+N AGG KE ER ++++MG + G GSG + KL +N L
Sbjct: 118 APVTGAVDGARNGNMTQFAGGDKETIERIRPVMELMGPVHY-MGSNGSGSITKLASNQLW 176
Query: 491 GITGMATAECMNMGIKMGLEPKVLLDVLNNSSARSWSTEVYCPVPGLVPTAPSSRNYDGG 312
I A E + M +K G+E + L ++ SW P + + +YD
Sbjct: 177 AIHATAMGEALVMAVKSGVELSRAWEALKIGASESWCMHHDAP-------SVFAGHYDPS 229
Query: 311 FKNELMVKDLEL 276
F +L KDL L
Sbjct: 230 FTLDLCQKDLNL 241
>UniRef50_A6GTB5 Cluster: 6-phosphogluconate dehydrogenase,
NAD-binding protein; n=1; Limnobacter sp. MED105|Rep:
6-phosphogluconate dehydrogenase, NAD-binding protein -
Limnobacter sp. MED105
Length = 299
Score = 66.9 bits (156), Expect = 6e-10
Identities = 35/95 (36%), Positives = 50/95 (52%)
Frame = -3
Query: 692 KGLGFTXAPVXGGVMGAQNVTXAFMAGGXKEDFERSLXLLKVMGXKQFHCGQIGSGQVAK 513
+G+ + PV GG GA+ T + MAGG F R +LK +G H G G+GQ K
Sbjct: 119 RGVDYIDCPVSGGAAGARAATLSMMAGGDLAAFNRIEPMLKHLGKTIRHVGPSGAGQAIK 178
Query: 512 LTNNMLMGITGMATAECMNMGIKMGLEPKVLLDVL 408
N M + I + AE MN ++ G E V+L++L
Sbjct: 179 AANQMALCIQLVGIAEAMNYALEQGAELSVVLELL 213
>UniRef50_A3WAC4 Cluster: Dehydrogenase; n=4; Bacteria|Rep:
Dehydrogenase - Erythrobacter sp. NAP1
Length = 301
Score = 66.5 bits (155), Expect = 8e-10
Identities = 48/176 (27%), Positives = 81/176 (46%)
Frame = -3
Query: 695 RKGLGFTXAPVXGGVMGAQNVTXAFMAGGXKEDFERSLXLLKVMGXKQFHCGQIGSGQVA 516
R GL APV GG GA+N + M GG +E + +++ + H G+ G+GQ A
Sbjct: 120 RLGLHAVDAPVSGGQAGAENGKLSIMCGGSEEAMASAQPVMQAYAARIVHIGEAGAGQTA 179
Query: 515 KLTNNMLMGITGMATAECMNMGIKMGLEPKVLLDVLNNSSARSWSTEVYCPVPGLVPTAP 336
K N + + +E + + G++ +++ ++ +A+SW E P +V
Sbjct: 180 KAINQVCIAGVLAGLSEGVRLAQATGVDTYKVVEAISGGAAQSWQMENRWPT--MV---- 233
Query: 335 SSRNYDGGFKNELMVKDLELASGMALGIRSPIPLGAVAXQLYRIVQSRGYGQKDFS 168
S +D GF + M KDL +A A + + + Q Y VQ+ G + D S
Sbjct: 234 -SGEFDFGFAIDWMRKDLAIALEEAGKHGLDMSVTKLVDQFYSEVQAAGGNRLDTS 288
>UniRef50_A1CAY2 Cluster: Oxidoreductase, acting on the CH-OH group
of donors, NAD or NADP as acceptor; n=2;
Aspergillus|Rep: Oxidoreductase, acting on the CH-OH
group of donors, NAD or NADP as acceptor - Aspergillus
clavatus
Length = 436
Score = 66.1 bits (154), Expect = 1e-09
Identities = 49/179 (27%), Positives = 81/179 (45%), Gaps = 3/179 (1%)
Frame = -3
Query: 695 RKGLGFTXAPVXGGVMGAQNVTXAFMAGGXKEDFERSLXLLKVMGX-KQFHC--GQIGSG 525
R + F PV GG A + T + MAG +E +L+VM K+ + G IG+G
Sbjct: 116 RADIRFIDCPVSGGAKRAADGTLSIMAGAPEEALNSGREILQVMSDQKKLYLVPGGIGAG 175
Query: 524 QVAKLTNNMLMGITGMATAECMNMGIKMGLEPKVLLDVLNNSSARSWSTEVYCPVPGLVP 345
K+ + +L GI + +E M ++GL+ K + + A +W E +P
Sbjct: 176 SNMKMVHQVLAGIHILGASEAMGFAAQLGLDAKTTAAKIIGTEAWTWMHE------NRLP 229
Query: 344 TAPSSRNYDGGFKNELMVKDLELASGMALGIRSPIPLGAVAXQLYRIVQSRGYGQKDFS 168
+ G +++KD+ + + A P+PL + A Q+Y +GYG KD S
Sbjct: 230 RMLAEDWNPGASALTIILKDVGIITTSARQHHFPVPLCSTAEQVYLSALLQGYGAKDDS 288
>UniRef50_Q9L7S0 Cluster: Uncharacterized oxidoreductase yihU; n=24;
Gammaproteobacteria|Rep: Uncharacterized oxidoreductase
yihU - Salmonella typhimurium
Length = 298
Score = 66.1 bits (154), Expect = 1e-09
Identities = 48/183 (26%), Positives = 83/183 (45%), Gaps = 1/183 (0%)
Frame = -3
Query: 692 KGLGFTXAPVXGGVMGAQNVTXAFMAGGXKEDFERSLXLLKVMGXKQFHCGQIGSGQVAK 513
KG P+ A T +AGG E ER+ +L MG + + G G G K
Sbjct: 112 KGFSMMDVPIGRTSDNAITGTLLLLAGGTAEQVERATPVLMAMGNELVNTGGPGMGIRVK 171
Query: 512 LTNNMLMGITGMATAECMNMGIKMGLEPKVLLDVLNNSSA-RSWSTEVYCPVPGLVPTAP 336
L NN + +AE + +GL V L V++ ++A + T + P
Sbjct: 172 LINNYMSIALNALSAEAAVLCEALGLSFDVALKVMSGTAAGKGHFTTTW-------PNKV 224
Query: 335 SSRNYDGGFKNELMVKDLELASGMALGIRSPIPLGAVAXQLYRIVQSRGYGQKDFSFVFQ 156
+ F +L KDL +A +A + P+PLGA + ++Y + ++ G G++D+S + +
Sbjct: 225 MKGDLSPAFMIDLAHKDLGIALDVANQLHVPMPLGAASREVYNLARAAGRGREDWSAILE 284
Query: 155 LLK 147
++
Sbjct: 285 QVR 287
>UniRef50_UPI0000D55E08 Cluster: PREDICTED: similar to CG4747-PA;
n=1; Tribolium castaneum|Rep: PREDICTED: similar to
CG4747-PA - Tribolium castaneum
Length = 267
Score = 65.7 bits (153), Expect = 1e-09
Identities = 47/182 (25%), Positives = 79/182 (43%)
Frame = -3
Query: 692 KGLGFTXAPVXGGVMGAQNVTXAFMAGGXKEDFERSLXLLKVMGXKQFHCGQIGSGQVAK 513
KG + A + G A++ + +A G K F+ K +G F+ G +GS
Sbjct: 91 KGGRYLEAQMQGSKKQAEDGSLIILAAGDKSLFDDCQTCFKAIGKTAFYLGTVGSATKMN 150
Query: 512 LTNNMLMGITGMATAECMNMGIKMGLEPKVLLDVLNNSSARSWSTEVYCPVPGLVPTAPS 333
L NM +GI AE M + + GL K L++ N S S Y G + S
Sbjct: 151 LCINMALGIGLAGLAESMVLAERCGLSCKDFLEIFNLSEGAS----NYLSNKGQLINNRS 206
Query: 332 SRNYDGGFKNELMVKDLELASGMALGIRSPIPLGAVAXQLYRIVQSRGYGQKDFSFVFQL 153
+ E M KD++L ++ ++ +P+ A A + Y+ + GY + D + VF
Sbjct: 207 FSKVEQAL--EYMQKDIKLCLDISNDVKQNLPVAAAANEAYKTARRSGYDEHDVALVFMK 264
Query: 152 LK 147
++
Sbjct: 265 MR 266
>UniRef50_A1ZWM5 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=1;
Microscilla marina ATCC 23134|Rep: 3-hydroxyisobutyrate
dehydrogenase - Microscilla marina ATCC 23134
Length = 295
Score = 65.7 bits (153), Expect = 1e-09
Identities = 52/179 (29%), Positives = 77/179 (43%), Gaps = 2/179 (1%)
Frame = -3
Query: 680 FTXAPVXGGVMGAQNVTXAFMAGGXKEDFERSLXLLKVMGXKQFHCGQIGSGQVAKLTNN 501
F APV G A+N F+ GG ++ +++MG K H G I K+ N
Sbjct: 115 FVEAPVAGTKSHAENAELVFLVGGGTTAIAQATPYMEMMGKKVVHIGAISKASALKILIN 174
Query: 500 MLMGITGMATAECMNMGIKMGLEPKVLLDVLNNSSARSWSTEVYCPVPGLVPTAPSSRNY 321
L+ +A AE + +G K GL+ + LL+ L N + P L A +
Sbjct: 175 YLLAQGMLAFAEALVVGEKQGLDRRFLLEFLPNLPVAA---------PFLKSKANKLMQH 225
Query: 320 DG--GFKNELMVKDLELASGMALGIRSPIPLGAVAXQLYRIVQSRGYGQKDFSFVFQLL 150
D F ELM KD+ L + A V+ LY+ +G G++DFS V+ L
Sbjct: 226 DAEVQFPLELMYKDITLFADTAEANNITNLSTDVSKNLYQTAIKQGLGREDFSAVYNSL 284
>UniRef50_A0K0Z6 Cluster: 6-phosphogluconate dehydrogenase,
NAD-binding precursor; n=2; Micrococcineae|Rep:
6-phosphogluconate dehydrogenase, NAD-binding precursor
- Arthrobacter sp. (strain FB24)
Length = 301
Score = 65.7 bits (153), Expect = 1e-09
Identities = 53/162 (32%), Positives = 71/162 (43%), Gaps = 3/162 (1%)
Frame = -3
Query: 692 KGLGFTXAPVXGGVMGAQNVTXAFMAGGXKEDFERSLX-LLKVMGXKQFHCGQIGSGQVA 516
+G F APV GG GA + + + GG + LL + G K H G GSG V
Sbjct: 110 QGAAFVDAPVSGGRDGAASGSLSAFVGGTDAALAAAEPVLLALTGGKYSHIGGPGSGNVV 169
Query: 515 KLTNNMLMGITGMATAECMNMGIKMGLEP-KVLLDVLNNSSARSWSTEVYCPVPGLVPTA 339
KL NN+L ++ E + + G++P K + S S +Y PT
Sbjct: 170 KLLNNVLAAANLVSVGEALGVAKAYGIDPAKAAASISEASGGSRVSANMY-------PTW 222
Query: 338 PSSRNYDGGFKNELMVKDLELASGMALGI-RSPIPLGAVAXQ 216
S +D GF LM +D LA +A I SP L AVA Q
Sbjct: 223 VLSGTHDSGFSLGLMARDAALAVEVAAQIGESPALLAAVAGQ 264
>UniRef50_A5VBF0 Cluster: 2-hydroxy-3-oxopropionate reductase
precursor; n=1; Sphingomonas wittichii RW1|Rep:
2-hydroxy-3-oxopropionate reductase precursor -
Sphingomonas wittichii RW1
Length = 298
Score = 65.3 bits (152), Expect = 2e-09
Identities = 48/176 (27%), Positives = 79/176 (44%), Gaps = 2/176 (1%)
Frame = -3
Query: 668 PVXGGVMGAQNVTXAFMAGGXKEDFERSLXLLKVMGXKQFHCGQIGSGQVAKLTNNMLMG 489
PV GGV GA+ T A +AGG +R LL ++ + G +G+GQ AKL N +++
Sbjct: 122 PVSGGVAGAEAGTLAILAGGDAAAIDRVRPLLALLSARVTRMGGVGAGQAAKLCNQLIVA 181
Query: 488 ITGMATAECMNMGIKMGLEPKVLLDVLNNSSARSWSTEVYCP--VPGLVPTAPSSRNYDG 315
+A AE M++G +G++ L A S +++ P P P P S
Sbjct: 182 TNMLAIAEAMHVGEALGIDLAQLPVAFQGGFADSRPLQLFGPRMAPPADPGPPVS----- 236
Query: 314 GFKNELMVKDLELASGMALGIRSPIPLGAVAXQLYRIVQSRGYGQKDFSFVFQLLK 147
+ M KD+ A + PL A ++ + G+G +D + +L +
Sbjct: 237 --ELRTMYKDIRSIRAAAAAAEAGTPLLAGVEAMWTRLIDAGHGGEDVPGLMRLYR 290
>UniRef50_A7I8V1 Cluster: 6-phosphogluconate dehydrogenase,
NAD-binding; n=1; Candidatus Methanoregula boonei
6A8|Rep: 6-phosphogluconate dehydrogenase, NAD-binding -
Methanoregula boonei (strain 6A8)
Length = 288
Score = 65.3 bits (152), Expect = 2e-09
Identities = 39/182 (21%), Positives = 83/182 (45%)
Frame = -3
Query: 689 GLGFTXAPVXGGVMGAQNVTXAFMAGGXKEDFERSLXLLKVMGXKQFHCGQIGSGQVAKL 510
G + PV G V+ A + G + +E LL +G ++ G+ KL
Sbjct: 113 GATYLECPVLGSVVPASQGKLTVLVSGDEGTYEVVKPLLSRIGSTLYYLGEPALATKMKL 172
Query: 509 TNNMLMGITGMATAECMNMGIKMGLEPKVLLDVLNNSSARSWSTEVYCPVPGLVPTAPSS 330
NN+++G AE + +G G++ ++D+L + + S V +
Sbjct: 173 INNLVLGSFMATCAEAVALGEAAGIDRGEVIDILLSGAGNSM-------VLAAKKDKLKN 225
Query: 329 RNYDGGFKNELMVKDLELASGMALGIRSPIPLGAVAXQLYRIVQSRGYGQKDFSFVFQLL 150
R + F + L+ KDL + ++ P+ +G+ +++ + +S+G ++DFS ++++
Sbjct: 226 REFSPHFSSALIYKDLHYLQDLCRTLKKPLFVGSTVKEVFALARSKGIDEQDFSVLYEVF 285
Query: 149 KE 144
+E
Sbjct: 286 RE 287
>UniRef50_Q39MY1 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=2;
Burkholderia sp. 383|Rep: 3-hydroxyisobutyrate
dehydrogenase - Burkholderia sp. (strain 383)
(Burkholderia cepacia (strain ATCC 17760/ NCIB 9086 /
R18194))
Length = 303
Score = 64.9 bits (151), Expect = 3e-09
Identities = 47/187 (25%), Positives = 89/187 (47%), Gaps = 1/187 (0%)
Frame = -3
Query: 695 RKGLGFTXAPVXGGVMGAQNVTXAFMAGGXKEDFERSLXLLKVMGXKQFHCG-QIGSGQV 519
++G+ APV GG A+ T A + G E+ LL+ +G + F G + G Q+
Sbjct: 113 QRGIDIVDAPVSGGPSAARAGTLAMLVSGMPSAVEQVSPLLERIGKEVFPMGDRPGMAQI 172
Query: 518 AKLTNNMLMGITGMATAECMNMGIKMGLEPKVLLDVLNNSSARSWSTEVYCPVPGLVPTA 339
K+ NN++M + AE + MG K GL+ ++ ++++ S +S++ C + +
Sbjct: 173 MKIVNNVVMAANLVVCAEGLAMGAKAGLDADRMMRLIDSGSGQSFA----C---SKIMSR 225
Query: 338 PSSRNYDGGFKNELMVKDLELASGMALGIRSPIPLGAVAXQLYRIVQSRGYGQKDFSFVF 159
S +D G ++ KD+ L A + +P A ++ G G +DF+ +
Sbjct: 226 AVSGAFDFGAALAVIEKDMALGLAEARLMDVAMPAIERARDVWHAAYEAGRGGEDFTSIL 285
Query: 158 QLLKEEN 138
+ ++E N
Sbjct: 286 RYVEERN 292
>UniRef50_A6P2M7 Cluster: Putative uncharacterized protein; n=2;
Bacteria|Rep: Putative uncharacterized protein -
Bacteroides capillosus ATCC 29799
Length = 321
Score = 64.5 bits (150), Expect = 3e-09
Identities = 49/170 (28%), Positives = 74/170 (43%)
Frame = -3
Query: 692 KGLGFTXAPVXGGVMGAQNVTXAFMAGGXKEDFERSLXLLKVMGXKQFHCGQIGSGQVAK 513
KGL APV GG GA+ T + + GG K DF+ L L + MG H G G+GQ AK
Sbjct: 146 KGLRPLDAPVTGGDTGAKAGTLSILVGGDKVDFDACLPLFQAMGKIIVHMGSAGAGQHAK 205
Query: 512 LTNNMLMGITGMATAECMNMGIKMGLEPKVLLDVLNNSSARSWSTEVYCPVPGLVPTAPS 333
L N + + E + GL LL ++ +A S+ + P + AP
Sbjct: 206 LANQIAIAGALSGVCEALTYARANGLNLDDLLSAISAGAAGSFQMQSLGPKMAVGDFAP- 264
Query: 332 SRNYDGGFKNELMVKDLELASGMALGIRSPIPLGAVAXQLYRIVQSRGYG 183
GF + +KD++L+ + I +P+ R ++ G G
Sbjct: 265 ------GFIMKHFIKDMKLSVEQSETIGLALPVLTQVLSECRSLEEAGLG 308
>UniRef50_Q8TT25 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=2;
Methanosarcina|Rep: 3-hydroxyisobutyrate dehydrogenase -
Methanosarcina acetivorans
Length = 300
Score = 64.5 bits (150), Expect = 3e-09
Identities = 44/186 (23%), Positives = 80/186 (43%)
Frame = -3
Query: 695 RKGLGFTXAPVXGGVMGAQNVTXAFMAGGXKEDFERSLXLLKVMGXKQFHCGQIGSGQVA 516
+ GL PV G A + GG +E + L +G + G G+G
Sbjct: 119 KAGLERLDTPVVGSKDLASKGELIILVGGSQEVLRKHEKFLNKLGKSVIYLGADGNGHKM 178
Query: 515 KLTNNMLMGITGMATAECMNMGIKMGLEPKVLLDVLNNSSARSWSTEVYCPVPGLVPTAP 336
KL N+ +G+ + +E + K+G + K ++ +NN+ R++ ++ G P
Sbjct: 179 KLAINLHLGLLAESFSEALVFSQKLGFDAKTFVETINNTPIRNYISQ------GKGPRIV 232
Query: 335 SSRNYDGGFKNELMVKDLELASGMALGIRSPIPLGAVAXQLYRIVQSRGYGQKDFSFVFQ 156
N++ F + KDL L + + +P+ V+ + Y G GQKDFS +
Sbjct: 233 EG-NFEPAFSLNNLAKDLRLVNEQITKTGAILPMTKVSIEEYSRTVQNGEGQKDFSVIAL 291
Query: 155 LLKEEN 138
++ +N
Sbjct: 292 EIQRKN 297
>UniRef50_Q1YHQ4 Cluster: Putative 2-hydroxy-3-oxopropionate
reductase; n=1; Aurantimonas sp. SI85-9A1|Rep: Putative
2-hydroxy-3-oxopropionate reductase - Aurantimonas sp.
SI85-9A1
Length = 292
Score = 64.1 bits (149), Expect = 5e-09
Identities = 48/179 (26%), Positives = 80/179 (44%)
Frame = -3
Query: 680 FTXAPVXGGVMGAQNVTXAFMAGGXKEDFERSLXLLKVMGXKQFHCGQIGSGQVAKLTNN 501
F APV GG A+ T A M GG ++ E + +L+ +G + H G IG+GQ KL N
Sbjct: 117 FVDAPVSGGPGAAETGTLAIMFGGSEQAAEAARPMLEQLG-RATHMGAIGTGQATKLVNQ 175
Query: 500 MLMGITGMATAECMNMGIKMGLEPKVLLDVLNNSSARSWSTEVYCPVPGLVPTAPSSRNY 321
+L AE + + G++ + L S + P AP
Sbjct: 176 VLCLTNYCVAAEALRLAQAYGVDAAKIPHALEPGLGNSAVLQAIYPRMVEEDFAPR---- 231
Query: 320 DGGFKNELMVKDLELASGMALGIRSPIPLGAVAXQLYRIVQSRGYGQKDFSFVFQLLKE 144
G+ +++ KD E+ +P+ A A ++R++ ++G G+ D + V +LL E
Sbjct: 232 --GYARQIL-KDFEMLHSATKAQHLALPMSAQAMTMFRMLVAQGDGELDGAAVVKLLPE 287
>UniRef50_A6EH53 Cluster: Putative uncharacterized protein; n=1;
Pedobacter sp. BAL39|Rep: Putative uncharacterized
protein - Pedobacter sp. BAL39
Length = 292
Score = 64.1 bits (149), Expect = 5e-09
Identities = 52/180 (28%), Positives = 78/180 (43%)
Frame = -3
Query: 689 GLGFTXAPVXGGVMGAQNVTXAFMAGGXKEDFERSLXLLKVMGXKQFHCGQIGSGQVAKL 510
G+ + APV G V A + M GG ++ F + LL MG H G G G AKL
Sbjct: 124 GIEYLDAPVSGSVKQATDGQLVIMVGGEEQAFHAAEPLLSCMGKLVMHLGASGIGNKAKL 183
Query: 509 TNNMLMGITGMATAECMNMGIKMGLEPKVLLDVLNNSSARSWSTEVYCPVPGLVPTAPSS 330
N L+ I AE + K + + LL +L N + + V+ + G A +
Sbjct: 184 AINTLLAIYTEGLAEIVTFSRKHQINTEDLLTLLGNGAL----SNVFTKIKG---DALLN 236
Query: 329 RNYDGGFKNELMVKDLELASGMALGIRSPIPLGAVAXQLYRIVQSRGYGQKDFSFVFQLL 150
NY F + MVKDL LA + PL A + ++ + +G++D V + L
Sbjct: 237 DNYQAAFALKHMVKDLNLAKDEGM----DTPLARTALETFKSA-AAAFGEEDVIAVIKQL 291
>UniRef50_Q4WV01 Cluster: Oxidoreductase, acting on the CH-OH group
of donors, NAD or NADP as acceptor; n=7;
Pezizomycotina|Rep: Oxidoreductase, acting on the CH-OH
group of donors, NAD or NADP as acceptor - Aspergillus
fumigatus (Sartorya fumigata)
Length = 435
Score = 63.3 bits (147), Expect = 8e-09
Identities = 49/179 (27%), Positives = 78/179 (43%), Gaps = 3/179 (1%)
Frame = -3
Query: 695 RKGLGFTXAPVXGGVMGAQNVTXAFMAGGXKEDFERSLXLLKVMGXKQ---FHCGQIGSG 525
R + F PV GG A + T + MAG +E +L+VM + G +G+G
Sbjct: 116 RADIRFIDCPVSGGAKRAADGTLSIMAGASEEALNSGREILQVMSDQNKLYLVPGGVGAG 175
Query: 524 QVAKLTNNMLMGITGMATAECMNMGIKMGLEPKVLLDVLNNSSARSWSTEVYCPVPGLVP 345
K+ + +L GI + +E M ++GL+ K + + S A +W E L
Sbjct: 176 SNMKMVHQVLAGIHILGASEAMGFAAQLGLDAKTTAEKIIGSEAWTWMHE-----NRLQR 230
Query: 344 TAPSSRNYDGGFKNELMVKDLELASGMALGIRSPIPLGAVAXQLYRIVQSRGYGQKDFS 168
N G +++KD+ + + A P PL + A Q+Y +GYG KD S
Sbjct: 231 MVEEDWN-PGASALTIILKDVGIITTSARQHHFPTPLCSTAEQVYLSALLQGYGPKDDS 288
>UniRef50_Q8F4I7 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=4;
Leptospira|Rep: 3-hydroxyisobutyrate dehydrogenase -
Leptospira interrogans
Length = 296
Score = 62.9 bits (146), Expect = 1e-08
Identities = 46/174 (26%), Positives = 76/174 (43%)
Frame = -3
Query: 692 KGLGFTXAPVXGGVMGAQNVTXAFMAGGXKEDFERSLXLLKVMGXKQFHCGQIGSGQVAK 513
K + F +P+ G A++ FM G + D + +V G +CG IG GQ AK
Sbjct: 112 KKIRFYDSPMTGSKNAARDGQILFMIGAKQVDIKDIQFFFEVCGKNAVYCGSIGGGQKAK 171
Query: 512 LTNNMLMGITGMATAECMNMGIKMGLEPKVLLDVLNNSSARSWSTEVYCPVPGLVPTAPS 333
L NM+ E + L+P +L ++L S+A+S E P
Sbjct: 172 LALNMIQAGIFQVYMEGFELAKNSELDPSILKEILLQSAAKSGIAEFKFPY-------VF 224
Query: 332 SRNYDGGFKNELMVKDLELASGMALGIRSPIPLGAVAXQLYRIVQSRGYGQKDF 171
S +Y+ F + M KD+ A +A ++ + L ++Y + + GY + DF
Sbjct: 225 SGDYETHFSLKNMRKDVYHAIELAKENKTNLSLCKNLPEIYDLGMNAGYAENDF 278
>UniRef50_A0QUD5 Cluster: 3-hydroxyisobutyrate dehydrogenase family
protein; n=1; Mycobacterium smegmatis str. MC2 155|Rep:
3-hydroxyisobutyrate dehydrogenase family protein -
Mycobacterium smegmatis (strain ATCC 700084 / mc(2)155)
Length = 326
Score = 62.9 bits (146), Expect = 1e-08
Identities = 47/186 (25%), Positives = 79/186 (42%)
Frame = -3
Query: 695 RKGLGFTXAPVXGGVMGAQNVTXAFMAGGXKEDFERSLXLLKVMGXKQFHCGQIGSGQVA 516
R G+ F APV GG ++ A G ++ FE + +L+V+ + G + ++
Sbjct: 119 RAGVHFLAAPVAGGPPVIESGGLAMAVSGDRQAFEHAADVLRVVAPNLIYVGPGDTSRLV 178
Query: 515 KLTNNMLMGITGMATAECMNMGIKMGLEPKVLLDVLNNSSARSWSTEVYCPVPGLVPTAP 336
K+ +N+L+ T E + G + LL L +++ S E P+
Sbjct: 179 KICHNLLVAATLEVLGELCVLAESHGASRQALLSFLRSTAISSRFIEYKAPLL------- 231
Query: 335 SSRNYDGGFKNELMVKDLELASGMALGIRSPIPLGAVAXQLYRIVQSRGYGQKDFSFVFQ 156
S ++ F + LM KDLEL G+A +P+ A YR G + D + V+
Sbjct: 232 ESLDFTPAFTSSLMQKDLELGLGLAGQADVTMPVTAQVHATYRAANESGLAELDAAAVYL 291
Query: 155 LLKEEN 138
L N
Sbjct: 292 YLAGSN 297
>UniRef50_Q46TQ0 Cluster: UDP-glucose/GDP-mannose
dehydrogenase:Prephenate dehydrogenase:NADP
oxidoreductase, coenzyme
F420-dependent:6-phosphogluconate dehydrogenase,
NAD-binding; n=1; Ralstonia eutropha JMP134|Rep:
UDP-glucose/GDP-mannose dehydrogenase:Prephenate
dehydrogenase:NADP oxidoreductase, coenzyme
F420-dependent:6-phosphogluconate dehydrogenase,
NAD-binding - Ralstonia eutropha (strain JMP134)
(Alcaligenes eutrophus)
Length = 294
Score = 62.5 bits (145), Expect = 1e-08
Identities = 43/179 (24%), Positives = 78/179 (43%)
Frame = -3
Query: 692 KGLGFTXAPVXGGVMGAQNVTXAFMAGGXKEDFERSLXLLKVMGXKQFHCGQIGSGQVAK 513
+ + + V G A+ + G + +ER LL +G QF+ G ++ K
Sbjct: 108 RDIAYLRVTVSGNNHMAEAAKLTALVSGPADAYERIKPLLAALGPAQFYLGDAEQARLMK 167
Query: 512 LTNNMLMGITGMATAECMNMGIKMGLEPKVLLDVLNNSSARSWSTEVYCPVPGLVPTAPS 333
L N+L+ +TG AE + +G K GLE + + DV+ S+ S P+ +
Sbjct: 168 LVVNLLIALTGGMLAEALTLGSKGGLEWQAMWDVITASAVAS-------PIVKAKAAQLA 220
Query: 332 SRNYDGGFKNELMVKDLELASGMALGIRSPIPLGAVAXQLYRIVQSRGYGQKDFSFVFQ 156
+Y F E M+KD+ L + P+ L A+ Q+ ++G D++ + +
Sbjct: 221 VHDYTPTFTVEQMLKDVGLILDAGAQLHVPMGLTALLGQMLHGAAAQGMAGDDYAAIIK 279
>UniRef50_A0RU56 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=1;
Cenarchaeum symbiosum|Rep: 3-hydroxyisobutyrate
dehydrogenase - Cenarchaeum symbiosum
Length = 282
Score = 62.1 bits (144), Expect = 2e-08
Identities = 44/184 (23%), Positives = 80/184 (43%), Gaps = 2/184 (1%)
Frame = -3
Query: 689 GLGFTXAPVXGGVMGAQNVTXAFMAGGXKEDFERSLXLLKVMGXKQFHCGQIGSGQVAKL 510
G+ APV GG A MA G K +E +L + K F+ G G+ KL
Sbjct: 103 GIRMVDAPVMGGPGAAMRGELVIMASGDKGAYEERRGILGAVSRKMFYLGGSGTAYSIKL 162
Query: 509 TNNMLMGITGMATAECMNMGIKMGLEPKVLLDVLNNSSARSW--STEVYCPVPGLVPTAP 336
N+ + + ++ +E + + ++P L+VLN++ + + + Y + G
Sbjct: 163 AMNLQIAMLAISLSEGITLARGASVDPHKFLEVLNSTYFNTGMSNNKAYKMIEG------ 216
Query: 335 SSRNYDGGFKNELMVKDLELASGMALGIRSPIPLGAVAXQLYRIVQSRGYGQKDFSFVFQ 156
+++ F + KDL + A R +PL +A ++Y G+G D++ +
Sbjct: 217 ---SFEPSFLLRNLKKDLHTINDHAESSRLKLPLSTLAEEVYSEAVKGGFGDLDYTGILA 273
Query: 155 LLKE 144
LKE
Sbjct: 274 YLKE 277
>UniRef50_A5WG80 Cluster: 6-phosphogluconate dehydrogenase,
NAD-binding; n=2; Moraxellaceae|Rep: 6-phosphogluconate
dehydrogenase, NAD-binding - Psychrobacter sp. PRwf-1
Length = 309
Score = 61.7 bits (143), Expect = 2e-08
Identities = 48/175 (27%), Positives = 72/175 (41%), Gaps = 1/175 (0%)
Frame = -3
Query: 689 GLGFTXAPVXGGVMGAQNVTXAFMAGGXKEDFERSLXLLKVMGXKQFHCGQIGSGQVAKL 510
G F APV G GA + T M GG + + + H G G+G K
Sbjct: 123 GCEFLDAPVSGQTSGADSGTLTVMVGGSAKALAYAKSAIDCFAGLIVHVGDSGAGFAVKA 182
Query: 509 TNNMLMGITGMATAECMNMGIKMGLEPKVLLDVLNNSSARSWSTEVYCPVPGLVPTAPSS 330
NN L I A E +++ G+ P L +N +S +S++T V +P +
Sbjct: 183 VNNTLFAINAWAAVEGLSVLKAHGVNPSDALACINKASGQSFATLV------TLPDRIVN 236
Query: 329 RNYDGGFKNELMVKDLELASGMALGIRSPIPLGAVAXQLYRIVQSR-GYGQKDFS 168
+ Y F +LM KD +A + + P P+ A L R ++ G DFS
Sbjct: 237 QTYPKTFTIDLMAKDCGIAIDLQTEKQVPTPVMAQVASLVRAASNQYEPGSADFS 291
>UniRef50_A5VEA3 Cluster: 2-hydroxy-3-oxopropionate reductase; n=1;
Sphingomonas wittichii RW1|Rep:
2-hydroxy-3-oxopropionate reductase - Sphingomonas
wittichii RW1
Length = 264
Score = 61.3 bits (142), Expect = 3e-08
Identities = 33/108 (30%), Positives = 53/108 (49%)
Frame = -3
Query: 692 KGLGFTXAPVXGGVMGAQNVTXAFMAGGXKEDFERSLXLLKVMGXKQFHCGQIGSGQVAK 513
+G+ APV GG GA+ T +FM GG + +R L ++ G G G+ +AK
Sbjct: 111 RGVVLVDAPVSGGAQGARARTMSFMVGGEEAALDRCQPLFELSGPNILRTGPAGTATLAK 170
Query: 512 LTNNMLMGITGMATAECMNMGIKMGLEPKVLLDVLNNSSARSWSTEVY 369
L + + + MA AE + +G GL +++ + ARSW E +
Sbjct: 171 LAHQVAIIGNIMAMAEAVRLGTAGGLSAEMVKQAVAGGLARSWIAETW 218
>UniRef50_Q6F842 Cluster: Putative 3-hydroxyisobutyrate
dehydrogenase or 2-hydroxy-3- oxopropionate reductase;
n=2; Acinetobacter|Rep: Putative 3-hydroxyisobutyrate
dehydrogenase or 2-hydroxy-3- oxopropionate reductase -
Acinetobacter sp. (strain ADP1)
Length = 291
Score = 60.5 bits (140), Expect = 6e-08
Identities = 41/178 (23%), Positives = 74/178 (41%)
Frame = -3
Query: 671 APVXGGVMGAQNVTXAFMAGGXKEDFERSLXLLKVMGXKQFHCGQIGSGQVAKLTNNMLM 492
+PV GG GA+ T AGG + + + V+ + G G+GQ K+ N +++
Sbjct: 119 SPVSGGTSGAEQGTLVIFAGGNESTIQDLGLIYNVLSQRVTRMGDTGTGQATKICNQLIV 178
Query: 491 GITGMATAECMNMGIKMGLEPKVLLDVLNNSSARSWSTEVYCPVPGLVPTAPSSRNYDGG 312
AE + + + G++ +L L N A S ++ P P
Sbjct: 179 AANSALIAEAVALAHRAGVDTTLLAPALANGFADSKPFQILAPRMARQIFEPVQ------ 232
Query: 311 FKNELMVKDLELASGMALGIRSPIPLGAVAXQLYRIVQSRGYGQKDFSFVFQLLKEEN 138
+K + + KDL A +A IP+ A Q GY Q D + + + +++++
Sbjct: 233 WKVQTLAKDLNNAVELATHYALDIPVAHQALHQLHSHQQNGYAQSDLATMIKQVEDQD 290
>UniRef50_A1WJN2 Cluster: 6-phosphogluconate dehydrogenase,
NAD-binding; n=3; Proteobacteria|Rep: 6-phosphogluconate
dehydrogenase, NAD-binding - Verminephrobacter eiseniae
(strain EF01-2)
Length = 297
Score = 60.5 bits (140), Expect = 6e-08
Identities = 42/123 (34%), Positives = 57/123 (46%), Gaps = 3/123 (2%)
Frame = -3
Query: 680 FTXAPVXGGVMGAQNVTXAFMAGGXKEDFERSLXLLKVMGXKQFHCGQIGSGQVAKLTNN 501
F APV AQ T A M G E F L+ CG +G GQV K+ NN
Sbjct: 122 FADAPVARTRAAAQAGTLAVMVGADPELFGVIEPLIATFASDIALCGPVGCGQVLKILNN 181
Query: 500 MLMGITGMATAECMNMGIKMGLEPKVLLDVLNNSSARSWSTE---VYCPVPGLVPTAPSS 330
M++ T +A +E +G K G++ VL D L N SA S++ + +PG P S
Sbjct: 182 MILFETVVAISEAKAIGEKAGVDASVLFDTLANGSADSFALRNHGMKAVLPGEFPERAFS 241
Query: 329 RNY 321
+Y
Sbjct: 242 VHY 244
>UniRef50_A7DSF1 Cluster: 2-hydroxy-3-oxopropionate reductase; n=1;
Candidatus Nitrosopumilus maritimus SCM1|Rep:
2-hydroxy-3-oxopropionate reductase - Candidatus
Nitrosopumilus maritimus SCM1
Length = 292
Score = 60.1 bits (139), Expect = 7e-08
Identities = 44/179 (24%), Positives = 80/179 (44%), Gaps = 2/179 (1%)
Frame = -3
Query: 668 PVXGGVMGAQNVTXAFMAGGXKEDFERSLXLLKVMGXKQFHCGQIGSGQVAKLTNNMLMG 489
PV GG A MA G KE FE + + + K F G+ G KL N+ +
Sbjct: 120 PVMGGPNVAITGDLVMMASGNKESFEECKKVFEKIANKVFFLGEKGVAHSIKLAMNLQIT 179
Query: 488 ITGMATAECMNMGIKMGLEPKVLLDVLNNSSARSWSTE--VYCPVPGLVPTAPSSRNYDG 315
+ +A +E + + K ++PK+ L++LN++ ++ +E + + G YD
Sbjct: 180 MLALALSEGITLVKKADVDPKIFLEILNSTYFKTGMSENKAFKMIDG---------KYDP 230
Query: 314 GFKNELMVKDLELASGMALGIRSPIPLGAVAXQLYRIVQSRGYGQKDFSFVFQLLKEEN 138
F E + KD+ + A + +P+ A ++Y G G D++ + + +K N
Sbjct: 231 TFTLENLKKDIITMTNAAKSLGIKLPMIEKAEEVYGNAVKEGLGGIDYTGIIEYIKRIN 289
>UniRef50_UPI0000EBE4FC Cluster: PREDICTED: hypothetical protein;
n=1; Bos taurus|Rep: PREDICTED: hypothetical protein -
Bos taurus
Length = 351
Score = 59.7 bits (138), Expect = 1e-07
Identities = 43/179 (24%), Positives = 74/179 (41%)
Frame = -3
Query: 692 KGLGFTXAPVXGGVMGAQNVTXAFMAGGXKEDFERSLXLLKVMGXKQFHCGQIGSGQVAK 513
+G F APV G + + +A G + +E + MG F G++G+
Sbjct: 176 RGGRFLEAPVSGNQQLSNDGMLVILAAGDRGLYEDCSSCFQAMGKTSFFLGEVGNAAKMM 235
Query: 512 LTNNMLMGITGMATAECMNMGIKMGLEPKVLLDVLNNSSARSWSTEVYCPVPGLVPTAPS 333
L NM+ G AE + + G + LLD+LN S + C ++
Sbjct: 236 LIVNMVQGSFMATIAEGLTLAQVTGQSQQTLLDILNQGQLASIFLDQKC--QNIL----- 288
Query: 332 SRNYDGGFKNELMVKDLELASGMALGIRSPIPLGAVAXQLYRIVQSRGYGQKDFSFVFQ 156
N+ F + + KDL LA + + P P+ A A ++Y+ ++ D S V++
Sbjct: 289 QGNFKPDFYLKYIQKDLRLAIALGDAVNHPTPMAAAANEVYKRAKALDQSDNDMSAVYR 347
>UniRef50_A4S5A4 Cluster: Predicted protein; n=2; Ostreococcus|Rep:
Predicted protein - Ostreococcus lucimarinus CCE9901
Length = 319
Score = 59.7 bits (138), Expect = 1e-07
Identities = 48/174 (27%), Positives = 75/174 (43%), Gaps = 1/174 (0%)
Frame = -3
Query: 680 FTXAPVXGGVMGAQNVTXAFMAGGXKEDFERSLXLLKVMGXKQFHCGQIGSGQV-AKLTN 504
F APV GG A F+ GG +E + VMG K++ G + AKL
Sbjct: 141 FLAAPVSGGWRDAAKGELLFLGGGDARAYEDGARFMDVMGAKRWLVGDSPTHAARAKLML 200
Query: 503 NMLMGITGMATAECMNMGIKMGLEPKVLLDVLNNSSARSWSTEVYCPVPGLVPTAPSSRN 324
++MG A E + + GL+ +L++L++S+ S P+ + RN
Sbjct: 201 QIMMGNVVGALGEMHALSERAGLDSNAILEMLSHSAMGS-------PLTTAKGKLMADRN 253
Query: 323 YDGGFKNELMVKDLELASGMALGIRSPIPLGAVAXQLYRIVQSRGYGQKDFSFV 162
+ F+ L KDL LA +A + P+ A Y +S G+ DF+ V
Sbjct: 254 FAPNFQVYLQQKDLRLALNLADELDFAAPITAATNAQYLKAKSLGHANSDFAAV 307
>UniRef50_Q49A26 Cluster: Cytokine-like nuclear factor n-pac; n=46;
Euteleostomi|Rep: Cytokine-like nuclear factor n-pac -
Homo sapiens (Human)
Length = 553
Score = 59.7 bits (138), Expect = 1e-07
Identities = 43/179 (24%), Positives = 74/179 (41%)
Frame = -3
Query: 692 KGLGFTXAPVXGGVMGAQNVTXAFMAGGXKEDFERSLXLLKVMGXKQFHCGQIGSGQVAK 513
+G F APV G + + +A G + +E + MG F G++G+
Sbjct: 378 RGGRFLEAPVSGNQQLSNDGMLVILAAGDRGLYEDCSSCFQTMGKTSFFLGEVGNAAKMM 437
Query: 512 LTNNMLMGITGMATAECMNMGIKMGLEPKVLLDVLNNSSARSWSTEVYCPVPGLVPTAPS 333
L NM+ G AE + + G + LLD+LN S + C ++
Sbjct: 438 LIVNMVQGSFMATIAEGLTLAQVTGRSQQTLLDILNQGQLASIFLDQKC--QNIL----- 490
Query: 332 SRNYDGGFKNELMVKDLELASGMALGIRSPIPLGAVAXQLYRIVQSRGYGQKDFSFVFQ 156
N+ F + + KDL LA + + P P+ A A ++Y+ ++ D S V++
Sbjct: 491 QGNFKPDFYLKYIQKDLRLAIALGDAVNHPTPMAAAANEVYKRAKALDQSDNDMSAVYR 549
>UniRef50_A1GFG2 Cluster: 6-phosphogluconate dehydrogenase,
NAD-binding; n=1; Salinispora arenicola CNS205|Rep:
6-phosphogluconate dehydrogenase, NAD-binding -
Salinispora arenicola CNS205
Length = 315
Score = 59.3 bits (137), Expect = 1e-07
Identities = 49/183 (26%), Positives = 71/183 (38%)
Frame = -3
Query: 695 RKGLGFTXAPVXGGVMGAQNVTXAFMAGGXKEDFERSLXLLKVMGXKQFHCGQIGSGQVA 516
++G F APV G A T F+AGG R +L+ +G H G G+G
Sbjct: 112 QRGAEFLDAPVLGSRPQADAGTLIFLAGGDLAVLHRIEPVLRQVGGAVHHMGPAGTGTQM 171
Query: 515 KLTNNMLMGITGMATAECMNMGIKMGLEPKVLLDVLNNSSARSWSTEVYCPVPGLVPTAP 336
KL N L + AE + L P ++ L +T V P TA
Sbjct: 172 KLLTNSLFAVQVATVAELIAALHGTDLAPGRAIEALA-------ATPVTGPAIATAATAM 224
Query: 335 SSRNYDGGFKNELMVKDLELASGMALGIRSPIPLGAVAXQLYRIVQSRGYGQKDFSFVFQ 156
+ F EL+ KDLE A+ A R+ +P YR + G+ + V +
Sbjct: 225 LGDTFPAAFPIELVAKDLEYATADAAARRATVPSTRTTTDTYRRAINHGHRNDHITGVIK 284
Query: 155 LLK 147
L +
Sbjct: 285 LFR 287
>UniRef50_Q0KC92 Cluster: 3-Hydroxyisobutyrate dehydrogenase; n=1;
Ralstonia eutropha H16|Rep: 3-Hydroxyisobutyrate
dehydrogenase - Ralstonia eutropha (strain ATCC 17699 /
H16 / DSM 428 / Stanier 337)(Cupriavidus necator (strain
ATCC 17699 / H16 / DSM 428 / Stanier337))
Length = 305
Score = 58.8 bits (136), Expect = 2e-07
Identities = 44/183 (24%), Positives = 79/183 (43%)
Frame = -3
Query: 695 RKGLGFTXAPVXGGVMGAQNVTXAFMAGGXKEDFERSLXLLKVMGXKQFHCGQIGSGQVA 516
R+G F APV G V A + + G + F+ +L + +Q + G +V
Sbjct: 122 RRGAAFLRAPVSGTVSLAASAQLSCFVSGPRPAFDAVQPVLACLTARQSYVGGADEARVI 181
Query: 515 KLTNNMLMGITGMATAECMNMGIKMGLEPKVLLDVLNNSSARSWSTEVYCPVPGLVPTAP 336
KL NM++ ++ E + G + GL +++D +N+S S
Sbjct: 182 KLMINMMVFMSTAVIGEGLAFGARAGLNRALMVDAINDSIVGSAHYRTKA-------EQL 234
Query: 335 SSRNYDGGFKNELMVKDLELASGMALGIRSPIPLGAVAXQLYRIVQSRGYGQKDFSFVFQ 156
R+Y L+VKDL+LA +A +P+ ++ Q ++Q R G D + +
Sbjct: 235 KQRDYAAVGPISLVVKDLDLALAVARDNAVALPMSSLVRQYLALMQQRRQGHLDIAALAD 294
Query: 155 LLK 147
+L+
Sbjct: 295 VLE 297
>UniRef50_A1SQ87 Cluster: 6-phosphogluconate dehydrogenase,
NAD-binding; n=4; Bacteria|Rep: 6-phosphogluconate
dehydrogenase, NAD-binding - Nocardioides sp. (strain
BAA-499 / JS614)
Length = 318
Score = 58.8 bits (136), Expect = 2e-07
Identities = 45/180 (25%), Positives = 78/180 (43%)
Frame = -3
Query: 692 KGLGFTXAPVXGGVMGAQNVTXAFMAGGXKEDFERSLXLLKVMGXKQFHCGQIGSGQVAK 513
+G+ F APV G + + + G +E +ER LL +G + G+ ++AK
Sbjct: 121 RGVAFLAAPVSGNGKVVRAGGLSLVVSGPEETYERVAHLLDHLGKGATYVGEGELARLAK 180
Query: 512 LTNNMLMGITGMATAECMNMGIKMGLEPKVLLDVLNNSSARSWSTEVYCPVPGLVPTAPS 333
+ +N+++G+ AE + K G+ L+ LN S S T P A
Sbjct: 181 ICHNVMLGVVTQCLAEITVLAEKGGMSRAAFLEFLNKSVMGSVFTTYKTP-------AFV 233
Query: 332 SRNYDGGFKNELMVKDLELASGMALGIRSPIPLGAVAXQLYRIVQSRGYGQKDFSFVFQL 153
+ +Y F L+ KD +L A + P+P+ A + S G ++DF+ + L
Sbjct: 234 NLDYTPTFTPILLRKDFDLGLAAARQLDVPMPVAAATNAAVQASVSSGRVEEDFAILLDL 293
>UniRef50_A0R1N4 Cluster: 6-phosphogluconate dehydrogenase,
NAD-binding; n=3; Mycobacterium|Rep: 6-phosphogluconate
dehydrogenase, NAD-binding - Mycobacterium smegmatis
(strain ATCC 700084 / mc(2)155)
Length = 272
Score = 58.8 bits (136), Expect = 2e-07
Identities = 32/102 (31%), Positives = 48/102 (47%)
Frame = -3
Query: 692 KGLGFTXAPVXGGVMGAQNVTXAFMAGGXKEDFERSLXLLKVMGXKQFHCGQIGSGQVAK 513
KG+ APV GG A+ T MAGG ++ ++ + G +GSGQVAK
Sbjct: 111 KGISLIDAPVSGGEPAAKAGTLLVMAGGDEDIVDKVRPVFATYADPVVRLGGVGSGQVAK 170
Query: 512 LTNNMLMGITGMATAECMNMGIKMGLEPKVLLDVLNNSSARS 387
+ NN+L A + +G +G+ L +V+ SA S
Sbjct: 171 ILNNLLFSANLGAAMSALELGEALGVPRSALCEVITRGSANS 212
>UniRef50_A7DWL2 Cluster: Putative dehydrogenase; n=1; Streptomyces
tendae|Rep: Putative dehydrogenase - Streptomyces tendae
Length = 293
Score = 58.4 bits (135), Expect = 2e-07
Identities = 50/174 (28%), Positives = 71/174 (40%), Gaps = 1/174 (0%)
Frame = -3
Query: 671 APVXGGVMGAQNVTXAFMAGGXKEDFERSLXLLKVMGXKQFHCGQIGSGQVAKLTNNMLM 492
A V G A++ G + + +L +G + H G G KL N+L+
Sbjct: 118 ACVMGNPEMAESGRLRIFTSGSHSAVDAAGDVLSALGQEVRHLGDAGRASALKLALNLLL 177
Query: 491 GITGMATAECMNMGIKMGLEPKVLLDVLNNSSARSWSTEVYCPVPGLVPTAPSSRNY-DG 315
GI AE + GL +LL+VL S RS PV G R Y
Sbjct: 178 GIQTAGLAEAVAFAEAAGLGRDLLLEVLLGSGWRS-------PVLGFRAEFMRRRTYTPA 230
Query: 314 GFKNELMVKDLELASGMALGIRSPIPLGAVAXQLYRIVQSRGYGQKDFSFVFQL 153
F+ LM KDLELA A + P+PL A + + G G +D + V ++
Sbjct: 231 AFRTRLMHKDLELALDQATAYQLPLPLVHRAQERFAGAIDAGRGDEDAAVVVEV 284
>UniRef50_A6F020 Cluster: Putative uncharacterized protein; n=1;
Marinobacter algicola DG893|Rep: Putative
uncharacterized protein - Marinobacter algicola DG893
Length = 286
Score = 58.4 bits (135), Expect = 2e-07
Identities = 31/95 (32%), Positives = 48/95 (50%)
Frame = -3
Query: 692 KGLGFTXAPVXGGVMGAQNVTXAFMAGGXKEDFERSLXLLKVMGXKQFHCGQIGSGQVAK 513
KGLGF APV G GA+ + GG + + +L+ H G +GSGQVAK
Sbjct: 108 KGLGFVDAPVVFGRQGAKEGQLGSLCGGDDKQVAKITPVLESYSKAVHHVGPVGSGQVAK 167
Query: 512 LTNNMLMGITGMATAECMNMGIKMGLEPKVLLDVL 408
NNML +A E +++ + G++ + + + L
Sbjct: 168 ACNNMLHWAACVANFEVLSLAKRYGIDAQQMRETL 202
>UniRef50_Q2CHC8 Cluster: Oxidoreductase; n=1; Oceanicola granulosus
HTCC2516|Rep: Oxidoreductase - Oceanicola granulosus
HTCC2516
Length = 288
Score = 57.6 bits (133), Expect = 4e-07
Identities = 30/103 (29%), Positives = 48/103 (46%)
Frame = -3
Query: 695 RKGLGFTXAPVXGGVMGAQNVTXAFMAGGXKEDFERSLXLLKVMGXKQFHCGQIGSGQVA 516
R + APV GG A+ + GG + D ER+ ++ + H G +G+GQ A
Sbjct: 106 RMDAAWIDAPVSGGPQLAETGELTMLLGGQERDIERARAVIDALAANATHLGPLGAGQAA 165
Query: 515 KLTNNMLMGITGMATAECMNMGIKMGLEPKVLLDVLNNSSARS 387
K N ++G+ + AE + + K G++P L L A S
Sbjct: 166 KTLNQAIVGVNYVLMAELLALARKSGIDPARLPQALAGGMADS 208
>UniRef50_Q3W3N3 Cluster: Putative uncharacterized protein; n=1;
Frankia sp. EAN1pec|Rep: Putative uncharacterized
protein - Frankia sp. EAN1pec
Length = 315
Score = 57.2 bits (132), Expect = 5e-07
Identities = 44/152 (28%), Positives = 63/152 (41%), Gaps = 2/152 (1%)
Frame = -3
Query: 725 PQTDFSL*P*RKGLGFTX--APVXGGVMGAQNVTXAFMAGGXKEDFERSLXLLKVMGXKQ 552
P+T L +G G T APV G +AGG + D +R + ++ G
Sbjct: 111 PRTCVDLAARARGRGITVLDAPVSNGAPDESGRQLVVLAGGDRRDVDRCAPVFELFGRTV 170
Query: 551 FHCGQIGSGQVAKLTNNMLMGITGMATAECMNMGIKMGLEPKVLLDVLNNSSARSWSTEV 372
+ G +GS Q+ KL NN L + A E + +GL+P + L SA + S
Sbjct: 171 VYTGDVGSAQLTKLVNNALFIVHRSAAIEALRAAGTLGLDPDGVRVALQECSANARS--- 227
Query: 371 YCPVPGLVPTAPSSRNYDGGFKNELMVKDLEL 276
P+PG P F L+ KDL L
Sbjct: 228 -LPIPGGPPIGGHGGPPPDAFV-ALLTKDLNL 257
>UniRef50_Q5LNV6 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=2;
Rhodobacteraceae|Rep: 3-hydroxyisobutyrate dehydrogenase
- Silicibacter pomeroyi
Length = 269
Score = 56.8 bits (131), Expect = 7e-07
Identities = 30/96 (31%), Positives = 45/96 (46%)
Frame = -3
Query: 671 APVXGGVMGAQNVTXAFMAGGXKEDFERSLXLLKVMGXKQFHCGQIGSGQVAKLTNNMLM 492
AP+ G + AQ +FM GG D + + L MG G GSG AK+ NN+L
Sbjct: 113 APMSGAQIAAQEARLSFMLGGEPADLDAAQPLFAAMGSHFHRMGPYGSGMQAKVLNNLLA 172
Query: 491 GITGMATAECMNMGIKMGLEPKVLLDVLNNSSARSW 384
T ++ GL+ LL +++ SS ++W
Sbjct: 173 AANTAMTRLVLDWADAAGLDEVALLRLIHTSSGQNW 208
>UniRef50_A1UJF2 Cluster: 6-phosphogluconate dehydrogenase,
NAD-binding; n=6; Actinomycetales|Rep:
6-phosphogluconate dehydrogenase, NAD-binding -
Mycobacterium sp. (strain KMS)
Length = 272
Score = 56.8 bits (131), Expect = 7e-07
Identities = 30/95 (31%), Positives = 44/95 (46%)
Frame = -3
Query: 671 APVXGGVMGAQNVTXAFMAGGXKEDFERSLXLLKVMGXKQFHCGQIGSGQVAKLTNNMLM 492
APV GG + M GG + D E++ + H G +GSGQV K+ NN+L
Sbjct: 118 APVSGGAPAVEQGKLLVMVGGEEADVEKARPVFATYADPIVHLGPLGSGQVTKILNNLLF 177
Query: 491 GITGMATAECMNMGIKMGLEPKVLLDVLNNSSARS 387
+ + +G +G+ L +VLN SA S
Sbjct: 178 TANLGSALSTLELGESLGIPRTQLAEVLNGGSATS 212
>UniRef50_A3VLN6 Cluster: Oxidoreductase; n=1; Rhodobacterales
bacterium HTCC2654|Rep: Oxidoreductase - Rhodobacterales
bacterium HTCC2654
Length = 293
Score = 56.4 bits (130), Expect = 9e-07
Identities = 32/99 (32%), Positives = 46/99 (46%)
Frame = -3
Query: 689 GLGFTXAPVXGGVMGAQNVTXAFMAGGXKEDFERSLXLLKVMGXKQFHCGQIGSGQVAKL 510
G + APV GG+ GA A GG D R+ +L +G H G GSGQVAK
Sbjct: 113 GAAWVDAPVSGGLAGAAAGQLAIFVGGEDADVTRAWPVLTTLGTTVTHLGPTGSGQVAKA 172
Query: 509 TNNMLMGITGMATAECMNMGIKMGLEPKVLLDVLNNSSA 393
N ++ ++ A AE + + + + P+ L L A
Sbjct: 173 CNQVIGFLSFAALAEALALAARYDIAPRDLAVALTGGFA 211
>UniRef50_Q1EPJ1 Cluster: 6-phosphogluconate dehydrogenase
NAD-binding domain-containing protein; n=8;
Magnoliophyta|Rep: 6-phosphogluconate dehydrogenase
NAD-binding domain-containing protein - Musa acuminata
(Banana)
Length = 314
Score = 56.0 bits (129), Expect = 1e-06
Identities = 52/178 (29%), Positives = 80/178 (44%), Gaps = 7/178 (3%)
Frame = -3
Query: 692 KGLGFTXAPVXGGVMGAQNVTXAFMAGGXKEDFERSLXLLKVMGXKQFHCGQIGSGQVAK 513
+G APV GG +GA++ T A +AGG + L + +G + G GSGQ +K
Sbjct: 127 RGCWAVDAPVSGGDVGARDGTLAILAGGDEGVVHWLSPLFEALGRATW-MGPAGSGQSSK 185
Query: 512 LTNNMLMGITGMATAECMNMGIKMGLEPKVLLDVLNNSSARSWSTEVYCPVPGLVPTAPS 333
+ N + +G T + +E + + GL+ LD + +A S + E++ AP
Sbjct: 186 IANQITIGGTILGLSEAIVFAGRAGLDVPRFLDAVRGGAAGSRAMEIFGERMARRDFAP- 244
Query: 332 SRNYDGGFKNELMVKDL-------ELASGMALGIRSPIPLGAVAXQLYRIVQSRGYGQ 180
GGF E MVKDL E G +P A+ QLY + + G G+
Sbjct: 245 -----GGFA-EYMVKDLGMGLRGGEDGGEEETGKGVVLPGAALCQQLYLAMVANGDGK 296
>UniRef50_Q9I1R8 Cluster: Probable dehydrogenase; n=7; Pseudomonas
aeruginosa|Rep: Probable dehydrogenase - Pseudomonas
aeruginosa
Length = 291
Score = 55.6 bits (128), Expect = 2e-06
Identities = 44/177 (24%), Positives = 82/177 (46%), Gaps = 1/177 (0%)
Frame = -3
Query: 695 RKGLGFTXAPVXGGVMGAQNVTXAFMAGGXKEDFERSLXLLKVMGXKQFHCGQIGSGQVA 516
R+GL F APV G A+ + GG +E E+ LL++MG K + G+ G +A
Sbjct: 108 RQGLAFVAAPVFGRTDVAEAGKLNIVVGGPEEAIEQVKALLEIMGQKTWFFGKDPRGAMA 167
Query: 515 -KLTNNMLMGITGMATAECMNMGIKMGLEPKVLLDVLNNSSARSWSTEVYCPVPGLVPTA 339
K++ N ++ + E + + ++G+EP ++++ S+ + VY P
Sbjct: 168 VKISGNFMIASAIESMGESVALVKRLGVEPGRFMELM---SSTLFDAPVY---RNYGPQI 221
Query: 338 PSSRNYDGGFKNELMVKDLELASGMALGIRSPIPLGAVAXQLYRIVQSRGYGQKDFS 168
R F+ L +KD++LA P+PL ++ + + G G+ D++
Sbjct: 222 VEQRFTPARFRLVLGLKDVDLALSAGKRHNVPLPLASLLHDVLLEAIAHGDGESDWT 278
>UniRef50_Q7NR40 Cluster: Probable 3-hydroxyisobutyrate
dehydrogenase; n=1; Chromobacterium violaceum|Rep:
Probable 3-hydroxyisobutyrate dehydrogenase -
Chromobacterium violaceum
Length = 296
Score = 55.6 bits (128), Expect = 2e-06
Identities = 33/101 (32%), Positives = 47/101 (46%)
Frame = -3
Query: 689 GLGFTXAPVXGGVMGAQNVTXAFMAGGXKEDFERSLXLLKVMGXKQFHCGQIGSGQVAKL 510
G AP+ G V A + T F+ GG + D E + LL +G H G +G+G AKL
Sbjct: 119 GWPLVEAPMTGSVHDASHGTLHFLVGGAEADVEWASPLLWALGRGVHHLGGLGAGNTAKL 178
Query: 509 TNNMLMGITGMATAECMNMGIKMGLEPKVLLDVLNNSSARS 387
N+L+G+ E + + GL LD L+ S S
Sbjct: 179 ALNLLVGVMAGGLGEAIALLRAHGLAVDSFLDALDGSGLAS 219
>UniRef50_A0NRG5 Cluster: 6-phosphogluconate dehydrogenase,
NAD-binding protein; n=1; Stappia aggregata IAM
12614|Rep: 6-phosphogluconate dehydrogenase, NAD-binding
protein - Stappia aggregata IAM 12614
Length = 291
Score = 55.6 bits (128), Expect = 2e-06
Identities = 45/183 (24%), Positives = 74/183 (40%)
Frame = -3
Query: 692 KGLGFTXAPVXGGVMGAQNVTXAFMAGGXKEDFERSLXLLKVMGXKQFHCGQIGSGQVAK 513
KG F APV G A++ MAG D L V+G K G+ G+G K
Sbjct: 112 KGRRFVDAPVSGATQAAKDAKLLIMAGATASDAPELAALFDVLGRKTIWLGKAGAGAAMK 171
Query: 512 LTNNMLMGITGMATAECMNMGIKMGLEPKVLLDVLNNSSARSWSTEVYCPVPGLVPTAPS 333
L NML+ AE +++ G+ + +V+ NS+A + V GL +
Sbjct: 172 LGVNMLIHGLNQTLAEALSLTTAAGIPQEQAYEVVENSAA---AAPVIAYRKGLYLDEAA 228
Query: 332 SRNYDGGFKNELMVKDLELASGMALGIRSPIPLGAVAXQLYRIVQSRGYGQKDFSFVFQL 153
++ F L KD+ LA +A +P + + + GY +D + +
Sbjct: 229 ---HEVSFTVALARKDVGLALELASTCGVVMPQAELNHAVLKAAGQAGYDGRDMASILSF 285
Query: 152 LKE 144
+ +
Sbjct: 286 VNK 288
>UniRef50_A0K107 Cluster: 2-hydroxy-3-oxopropionate reductase; n=1;
Arthrobacter sp. FB24|Rep: 2-hydroxy-3-oxopropionate
reductase - Arthrobacter sp. (strain FB24)
Length = 302
Score = 55.6 bits (128), Expect = 2e-06
Identities = 44/180 (24%), Positives = 74/180 (41%)
Frame = -3
Query: 689 GLGFTXAPVXGGVMGAQNVTXAFMAGGXKEDFERSLXLLKVMGXKQFHCGQIGSGQVAKL 510
GL AP+ GG +GA+ + M GG E ER L + H G+ G+G K
Sbjct: 128 GLTVVDAPLSGGTIGAEEGRLSIMVGGPAEAVERLTPLFGLYSSTAVHFGKTGAGSTVKA 187
Query: 509 TNNMLMGITGMATAECMNMGIKMGLEPKVLLDVLNNSSARSWSTEVYCPVPGLVPTAPSS 330
N +++ T A AE M + L+ + + L A S V
Sbjct: 188 CNQIVVAATVNALAEAMALASTAALDLEKVQTTLAGGLANS-------EVLRQKGHRWID 240
Query: 329 RNYDGGFKNELMVKDLELASGMALGIRSPIPLGAVAXQLYRIVQSRGYGQKDFSFVFQLL 150
++++GG + +KDL + +A +PL A + + + G G D + +++ L
Sbjct: 241 QDFEGGGSAKNQLKDLNFIAEIAAAHGINLPLAACLQSSFEEMIAAGDGDMDHTGIYRTL 300
>UniRef50_Q5FQ06 Cluster: Putative oxidoreductase; n=1;
Gluconobacter oxydans|Rep: Putative oxidoreductase -
Gluconobacter oxydans (Gluconobacter suboxydans)
Length = 290
Score = 55.2 bits (127), Expect = 2e-06
Identities = 47/186 (25%), Positives = 75/186 (40%)
Frame = -3
Query: 689 GLGFTXAPVXGGVMGAQNVTXAFMAGGXKEDFERSLXLLKVMGXKQFHCGQIGSGQVAKL 510
G AP+ G A+ + GG + +R+ +L V+G H G GS KL
Sbjct: 109 GFSLLDAPMSGSTPEAETGDLVMLVGGDEAVVKRAQPVLDVIGKLTIHAGPAGSAARLKL 168
Query: 509 TNNMLMGITGMATAECMNMGIKMGLEPKVLLDVLNNSSARSWSTEVYCPVPGLVPTAPSS 330
N +MG T AE ++ G+ GL+ V+ D L V P +
Sbjct: 169 VVNGVMGATLNVIAEGVSYGLAAGLDRDVVFDTLQ-------QVAVVSPHHKRKLKMGQN 221
Query: 329 RNYDGGFKNELMVKDLELASGMALGIRSPIPLGAVAXQLYRIVQSRGYGQKDFSFVFQLL 150
R + F LM KD+ L + + +P AVA Q + +R + +D+S + +
Sbjct: 222 REFPSQFPTRLMSKDMGLLLDAGRKVGAFMPGMAVADQALAL-SNRLHANEDYSALIGAM 280
Query: 149 KEENXN 132
+ N
Sbjct: 281 EHSVAN 286
>UniRef50_Q01PV6 Cluster: 6-phosphogluconate dehydrogenase,
NAD-binding; n=1; Solibacter usitatus Ellin6076|Rep:
6-phosphogluconate dehydrogenase, NAD-binding -
Solibacter usitatus (strain Ellin6076)
Length = 267
Score = 55.2 bits (127), Expect = 2e-06
Identities = 45/186 (24%), Positives = 75/186 (40%), Gaps = 2/186 (1%)
Frame = -3
Query: 695 RKGLGFTXAPVXGGVMGAQNVTXAFMAGGXKEDFERSLXLLKVMGXKQFHCGQIGSGQVA 516
+ G+ + A V G ++ MAGG +E F+ + L + + F+ G G+G
Sbjct: 90 KSGVDYLDATVLGSSKVVRSGAAVVMAGGRRESFDAASPLFRTFASRAFYLGPFGAGARM 149
Query: 515 KLTNNMLMGITGMATAECMNMGIKMGLEPKVLLDVLNNSSARSWSTEVYCPVPGLVPTAP 336
KL N+ +G+ AE + + P V L+VL +A S E
Sbjct: 150 KLVVNLALGLHRAVLAETLAFAHACEVSPTVALEVLKAGAAYSRVME---------DKGE 200
Query: 335 SSRNYDGGFKNELM--VKDLELASGMALGIRSPIPLGAVAXQLYRIVQSRGYGQKDFSFV 162
++D + L +KD+ L A + PL V QL + + GYG D S +
Sbjct: 201 KMLHHDFTVEARLSQHLKDVRLILDAAAAKHAKTPLSQVHRQLLEGLVTAGYGDADNSAI 260
Query: 161 FQLLKE 144
++
Sbjct: 261 MMAYEQ 266
>UniRef50_A0GPK7 Cluster: 6-phosphogluconate dehydrogenase,
NAD-binding; n=4; Burkholderia|Rep: 6-phosphogluconate
dehydrogenase, NAD-binding - Burkholderia phytofirmans
PsJN
Length = 297
Score = 55.2 bits (127), Expect = 2e-06
Identities = 47/168 (27%), Positives = 70/168 (41%)
Frame = -3
Query: 671 APVXGGVMGAQNVTXAFMAGGXKEDFERSLXLLKVMGXKQFHCGQIGSGQVAKLTNNMLM 492
APV GG GA T A MAGG E +L+ + G G+GQ KL N ++
Sbjct: 124 APVSGGTSGAAAGTLAIMAGGDATLIETLTPILRGYAARVTRMGGSGAGQATKLANQTIV 183
Query: 491 GITGMATAECMNMGIKMGLEPKVLLDVLNNSSARSWSTEVYCPVPGLVPTAPSSRNYDGG 312
T A AE + G++ + L A S + P +VP A +S G
Sbjct: 184 MTTIAALAEATRLARHAGIDTARIPAALAGGWADSVLLQTLMP-RMIVPPAQAS----GT 238
Query: 311 FKNELMVKDLELASGMALGIRSPIPLGAVAXQLYRIVQSRGYGQKDFS 168
+ M+KDL+ +A + +P+ A+ + +G G D S
Sbjct: 239 IRT--MLKDLDAVESLARESDTTLPVAALVRRWLTQAVEQGLGDADIS 284
>UniRef50_Q84H84 Cluster: Putative oxidoreductase; n=1; Arthrobacter
sp. BP2|Rep: Putative oxidoreductase - Arthrobacter sp.
BP2
Length = 278
Score = 54.8 bits (126), Expect = 3e-06
Identities = 32/97 (32%), Positives = 49/97 (50%), Gaps = 1/97 (1%)
Frame = -3
Query: 671 APVXGGVMGAQNVTXAFMAGGXKEDFERSLXLLKVMGXKQFHCG-QIGSGQVAKLTNNML 495
A V GG GA+ T + MA G ++ + +G F+ G + G+ Q AKL NN++
Sbjct: 122 AAVSGGSTGAEAGTLSIMASGAEDVVTAASPYFDAVGSNTFYYGSKPGNSQAAKLVNNLV 181
Query: 494 MGITGMATAECMNMGIKMGLEPKVLLDVLNNSSARSW 384
+GI A AE + G + L LL++ S+ SW
Sbjct: 182 LGINMNAVAEGLKFGAQYNLPEAELLNLFKVSTGDSW 218
>UniRef50_Q20XN2 Cluster: 6-phosphogluconate dehydrogenase,
NAD-binding; n=1; Rhodopseudomonas palustris BisB18|Rep:
6-phosphogluconate dehydrogenase, NAD-binding -
Rhodopseudomonas palustris (strain BisB18)
Length = 365
Score = 54.8 bits (126), Expect = 3e-06
Identities = 46/175 (26%), Positives = 76/175 (43%), Gaps = 1/175 (0%)
Frame = -3
Query: 689 GLGFTXAPVXGGVMGAQNVTXAFMAGGXKEDFERSLXLLKVMGXKQFHCGQ-IGSGQVAK 513
G G+ APV G A+ T +A G +++ LL +G K F G+ + + K
Sbjct: 131 GQGYVAAPVLGNPDLARARTLFILAAGPDAAMQKARPLLDRLGQKLFVIGEDAAAANLVK 190
Query: 512 LTNNMLMGITGMATAECMNMGIKMGLEPKVLLDVLNNSSARSWSTEVYCPVPGLVPTAPS 333
L N+L +T + E + + K G++P+V D+ NS + + V+ G +
Sbjct: 191 LAGNVLTALTLQSMGEVLALLRKSGIDPRVGFDIFTNSL---FDSRVHRTYGGKIV---D 244
Query: 332 SRNYDGGFKNELMVKDLELASGMALGIRSPIPLGAVAXQLYRIVQSRGYGQKDFS 168
R G L VKDL LA A P+P ++ + + G+ D+S
Sbjct: 245 ERYSPPGMTVPLAVKDLRLALAEAETNSVPMPATSLVRDRLVAMVAHGWADLDWS 299
>UniRef50_A3Y8R5 Cluster: Putative dehydrogenase; n=1; Marinomonas
sp. MED121|Rep: Putative dehydrogenase - Marinomonas sp.
MED121
Length = 297
Score = 54.8 bits (126), Expect = 3e-06
Identities = 45/182 (24%), Positives = 70/182 (38%)
Frame = -3
Query: 686 LGFTXAPVXGGVMGAQNVTXAFMAGGXKEDFERSLXLLKVMGXKQFHCGQIGSGQVAKLT 507
L APV GG GA T + G ++ + +L G G+G V KL
Sbjct: 116 LSLIDAPVTGGAEGAAAGTLTMLLGIDEQILTKFTSMLNAFTKNAIRMGPSGAGYVTKLA 175
Query: 506 NNMLMGITGMATAECMNMGIKMGLEPKVLLDVLNNSSARSWSTEVYCPVPGLVPTAPSSR 327
L + E + MG K L VL +L NS A+S+ + Y P
Sbjct: 176 QLHLNYLVAQGIGEALMMGAKAELNLDVLHKILQNSCAQSYVVDSYIP-------KVLDG 228
Query: 326 NYDGGFKNELMVKDLELASGMALGIRSPIPLGAVAXQLYRIVQSRGYGQKDFSFVFQLLK 147
+YD F L KD+ L + + + + LG Y+ + + V +L++
Sbjct: 229 SYDQSFALGLATKDMRLITELGSHLGIDMQLGNQVYHTYQEATEKYGPEVPHLSVLKLIE 288
Query: 146 EE 141
E+
Sbjct: 289 EQ 290
>UniRef50_A1WS34 Cluster: Putative uncharacterized protein; n=1;
Verminephrobacter eiseniae EF01-2|Rep: Putative
uncharacterized protein - Verminephrobacter eiseniae
(strain EF01-2)
Length = 173
Score = 54.4 bits (125), Expect = 4e-06
Identities = 26/55 (47%), Positives = 35/55 (63%)
Frame = -3
Query: 377 EVYCPVPGLVPTAPSSRNYDGGFKNELMVKDLELASGMALGIRSPIPLGAVAXQL 213
E Y P+PG++ T+P S+NY GGF +LM KD LA A +R+ PLG +A L
Sbjct: 13 EKYDPMPGVMETSPVSKNYAGGFGTDLMPKDPGLAQENAPAVRAATPLGGLARSL 67
>UniRef50_A3ET09 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=3;
Bacteria|Rep: 3-hydroxyisobutyrate dehydrogenase -
Leptospirillum sp. Group II UBA
Length = 311
Score = 54.0 bits (124), Expect = 5e-06
Identities = 48/180 (26%), Positives = 73/180 (40%)
Frame = -3
Query: 692 KGLGFTXAPVXGGVMGAQNVTXAFMAGGXKEDFERSLXLLKVMGXKQFHCGQIGSGQVAK 513
+G A + + A+ T M GG KE FER +L+ M G G K
Sbjct: 121 RGADCLEASMASSITQAREGTLYLMVGGKKEAFERVRPVLEAMSASLRWIGPAGQAAKIK 180
Query: 512 LTNNMLMGITGMATAECMNMGIKMGLEPKVLLDVLNNSSARSWSTEVYCPVPGLVPTAPS 333
NM+M I AE + + +GL+ ++ +V + + A S E G
Sbjct: 181 ALVNMVMNINTAGLAEGLGLADALGLDLAMVREVFSQTGAASRVLE----TDG---ADMQ 233
Query: 332 SRNYDGGFKNELMVKDLELASGMALGIRSPIPLGAVAXQLYRIVQSRGYGQKDFSFVFQL 153
+R +D F KD +A +A + +PL A Y + S G G+ D S V +L
Sbjct: 234 NREHDVYFSAAHAAKDSRIALALAARVGLNLPLAKAASGQYDRMVSLGLGEIDKSGVSEL 293
>UniRef50_A1WEB7 Cluster: 6-phosphogluconate dehydrogenase,
NAD-binding; n=1; Verminephrobacter eiseniae EF01-2|Rep:
6-phosphogluconate dehydrogenase, NAD-binding -
Verminephrobacter eiseniae (strain EF01-2)
Length = 293
Score = 54.0 bits (124), Expect = 5e-06
Identities = 45/181 (24%), Positives = 80/181 (44%), Gaps = 2/181 (1%)
Frame = -3
Query: 689 GLGFTXAPVXGGV--MGAQNVTXAFMAGGXKEDFERSLXLLKVMGXKQFHCGQIGSGQVA 516
G+ A + GV M A + T A GG + RS +L + +Q H G +G+G A
Sbjct: 106 GVDVVDASILAGVEQMAAGSATLAL--GGKPDAIARSQGVLDAIASRQIHFGALGAGAAA 163
Query: 515 KLTNNMLMGITGMATAECMNMGIKMGLEPKVLLDVLNNSSARSWSTEVYCPVPGLVPTAP 336
K+ NN + + AE M G+ + L+ +L++ ++ P+
Sbjct: 164 KVINNAVAHAVMVVVAEAGAMATAAGVGCEKLIALLSDP-----RMGLHRPLTYRYAQRV 218
Query: 335 SSRNYDGGFKNELMVKDLELASGMALGIRSPIPLGAVAXQLYRIVQSRGYGQKDFSFVFQ 156
+Y GG + KD LA +A + P+ A +Y I + G+G++D++ + +
Sbjct: 219 VKGDYTGGMPLDAARKDSTLALQLAQTLGVPLFAIQGAHSVYDIAAAAGHGRQDYAVIAK 278
Query: 155 L 153
L
Sbjct: 279 L 279
>UniRef50_UPI0001597301 Cluster: YfjR; n=1; Bacillus
amyloliquefaciens FZB42|Rep: YfjR - Bacillus
amyloliquefaciens FZB42
Length = 286
Score = 53.6 bits (123), Expect = 6e-06
Identities = 48/184 (26%), Positives = 83/184 (45%), Gaps = 2/184 (1%)
Frame = -3
Query: 692 KGLGFTXAPVXGGVMGAQNVTXAFMAGGXKEDFERSLXLLKVMGXKQFHCGQ-IGSGQVA 516
+G F APV G A+ + G E +++ LL ++ + F G+ + A
Sbjct: 111 RGQSFIAAPVLGRPDAAEKAELRIITAGPAEAKKKAEPLLNILSQQVFDTGEETKTANAA 170
Query: 515 KLTNNMLMGITGMATAECMNMGIKMGLEPKVLLDVLNNSSARSWSTEVYCPVPGLVPTAP 336
K++ N L+ A +E M K GLE K L++ + A S PV T
Sbjct: 171 KISVNFLLVSMLEALSESFLMMEKYGLEQKQFLEI---AGALFGS-----PVYQNYGTMM 222
Query: 335 SSRNYD-GGFKNELMVKDLELASGMALGIRSPIPLGAVAXQLYRIVQSRGYGQKDFSFVF 159
+ + ++ GFK L +KD LA A + + +PL +A + ++G+G D++ +
Sbjct: 223 AEQKFEPAGFKMSLGLKDTNLALAAAEQVSAKLPLAELAKSHFESGIAQGFGDLDWAALI 282
Query: 158 QLLK 147
+ LK
Sbjct: 283 KCLK 286
>UniRef50_A0LTQ8 Cluster: 6-phosphogluconate dehydrogenase,
NAD-binding precursor; n=1; Acidothermus cellulolyticus
11B|Rep: 6-phosphogluconate dehydrogenase, NAD-binding
precursor - Acidothermus cellulolyticus (strain ATCC
43068 / 11B)
Length = 305
Score = 53.2 bits (122), Expect = 8e-06
Identities = 48/176 (27%), Positives = 75/176 (42%), Gaps = 1/176 (0%)
Frame = -3
Query: 692 KGLGFTXAPVXGGVMGAQNVTXAFMAGGXKEDFERSLXLLKVMGXKQFHCGQIGSGQVAK 513
KG PV G V A+ M GG + +L ++G + FH G +GSG K
Sbjct: 113 KGADILDVPVSGSVAVAREGGLTLMVGGEDASLDAIRPVLDIIGRRIFHLGPLGSGAAMK 172
Query: 512 LTNNMLMGITGMATAECMNMGIKMGLEPKVLLDVLNNSSARSWSTEVYCPVPGLVPTAPS 333
L N ++ A AE + + + G+ + DV +S+A + + P
Sbjct: 173 LAVNTVIHGLNAALAEGLVLAERAGIPRSLAYDVFASSAAGA----PFVHYKRQAFEDPE 228
Query: 332 SRNYDGGFKNELMVKDLELASGMALGIRSPIPLGAVAXQLYRIVQSRGY-GQKDFS 168
D F+ L+ KDLEL +ALG ++ PL A L + + + G +D S
Sbjct: 229 HAPVD--FRLALVRKDLELI--LALGEQTGTPLPQAAKNLAIVAAALDHVGDRDIS 280
>UniRef50_Q4Q9Z1 Cluster: Dehydrogenase-like protein; n=6;
Trypanosomatidae|Rep: Dehydrogenase-like protein -
Leishmania major
Length = 431
Score = 53.2 bits (122), Expect = 8e-06
Identities = 39/141 (27%), Positives = 59/141 (41%), Gaps = 1/141 (0%)
Frame = -3
Query: 695 RKGLGFTXAPVXGGVMGAQNVTXAFMAGGXKEDFERSLXLLKVMGXKQFHCGQIGSGQVA 516
R+G F AP+ G A N M GG E +R + ++ H G GSG A
Sbjct: 129 RRGAVFLDAPMSGSPKQAFNNQLVLMVGGPAEQVQRVSPIFRMYADHIHHMGANGSGTAA 188
Query: 515 KLTNNMLMGITGMATAECMNMGIKMGLEP-KVLLDVLNNSSARSWSTEVYCPVPGLVPTA 339
KL + L+ A AE M + ++G+E + L+ VL+ S S P +
Sbjct: 189 KLLSQALVASHNAAAAEAMTIANRLGIEDYQKLIQVLDASWGSSTMLRRNAPTMQDLVRN 248
Query: 338 PSSRNYDGGFKNELMVKDLEL 276
P G + +++DL L
Sbjct: 249 PDKLAPSSGASIDNLLEDLAL 269
>UniRef50_A0YMN9 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=3;
Cyanobacteria|Rep: 3-hydroxyisobutyrate dehydrogenase -
Lyngbya sp. PCC 8106
Length = 371
Score = 52.8 bits (121), Expect = 1e-05
Identities = 39/128 (30%), Positives = 63/128 (49%), Gaps = 5/128 (3%)
Frame = -3
Query: 626 AFMAGGXKEDFERSLXLLKVMGXKQFHCGQIGSGQVAKLTNNMLMGITGMATAECMNMGI 447
A +A G + FER LL++M + +CG+IGSG KL +N + + A +E + +G+
Sbjct: 153 AVLASGSRATFERVEPLLQLMADQVLYCGEIGSGTRCKLIHNAVNAVAVQAVSEGITLGL 212
Query: 446 KMGLEPKVLLDVLNNSSARSWSTEVYCPVPGLVPTAPSSRNYD-----GGFKNELMVKDL 282
G+ + + D L S +++ GL P SR D F +L+ KDL
Sbjct: 213 AQGISLETIWDTLRFGSFGQNPGDIH----GL-PYYWFSRRCDHLSKPPAFTVKLLHKDL 267
Query: 281 ELASGMAL 258
+A MA+
Sbjct: 268 RIALDMAI 275
>UniRef50_A6R0U9 Cluster: Predicted protein; n=1; Ajellomyces
capsulatus NAm1|Rep: Predicted protein - Ajellomyces
capsulatus NAm1
Length = 444
Score = 52.8 bits (121), Expect = 1e-05
Identities = 46/177 (25%), Positives = 71/177 (40%), Gaps = 3/177 (1%)
Frame = -3
Query: 695 RKGLGFTXAPVXGGVMGAQNVTXAFMAGGXKEDFERSLXLLKVMGXKQ---FHCGQIGSG 525
R+ + F APV GG A T MAGG E LL M F G +G+G
Sbjct: 119 REDVYFIDAPVSGGARKAGEGTLTIMAGGSDAALEEGKFLLTEMADTNKLYFVPGGVGAG 178
Query: 524 QVAKLTNNMLMGITGMATAECMNMGIKMGLEPKVLLDVLNNSSARSWSTEVYCPVPGLVP 345
K+ + + I +A +E M +GL + + +S A S+ E C
Sbjct: 179 SNMKMIHQVFAAIHILAASEVMGFAAHLGLNAEEAGKAVTSSLAWSFMHENRC------E 232
Query: 344 TAPSSRNYDGGFKNELMVKDLELASGMALGIRSPIPLGAVAXQLYRIVQSRGYGQKD 174
Y G +++KD+ + + A P PL ++A Q++ G+G D
Sbjct: 233 RMLREDYYPGASAITIILKDVGIVTAAARLHNFPTPLCSIAEQIFITALPLGFGGDD 289
>UniRef50_Q3WJ00 Cluster: 6-phosphogluconate dehydrogenase, NAD
binding domain; n=1; Frankia sp. EAN1pec|Rep:
6-phosphogluconate dehydrogenase, NAD binding domain -
Frankia sp. EAN1pec
Length = 438
Score = 52.4 bits (120), Expect = 1e-05
Identities = 42/144 (29%), Positives = 55/144 (38%)
Frame = -3
Query: 689 GLGFTXAPVXGGVMGAQNVTXAFMAGGXKEDFERSLXLLKVMGXKQFHCGQIGSGQVAKL 510
GL APV GG A M GG + LL + H G +G+G AKL
Sbjct: 281 GLRVLDAPVSGGQPRALAGELTIMIGGDADTLADVAELLSALSNHVVHLGAVGAGSYAKL 340
Query: 509 TNNMLMGITGMATAECMNMGIKMGLEPKVLLDVLNNSSARSWSTEVYCPVPGLVPTAPSS 330
NN + + M G +G++P L VL SS+ ++ V L A S
Sbjct: 341 INNTMFAAQIALADDAMKAGESLGIDPAGLAAVLATSSSACIASGVRLRAGSLAGLADSP 400
Query: 329 RNYDGGFKNELMVKDLELASGMAL 258
N LM + L A G L
Sbjct: 401 ANLTLTKDATLMAEILGDAPGNGL 424
>UniRef50_Q98I20 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=2;
Alphaproteobacteria|Rep: 3-hydroxyisobutyrate
dehydrogenase - Rhizobium loti (Mesorhizobium loti)
Length = 305
Score = 52.0 bits (119), Expect = 2e-05
Identities = 44/155 (28%), Positives = 66/155 (42%)
Frame = -3
Query: 692 KGLGFTXAPVXGGVMGAQNVTXAFMAGGXKEDFERSLXLLKVMGXKQFHCGQIGSGQVAK 513
+G+ PV GGV A + GG +ER ++ M + F G IGS V K
Sbjct: 113 EGVETLECPVTGGVHLAAVGKITALVGGDAALYERHRAAIEAMCARSFLMGPIGSAAVIK 172
Query: 512 LTNNMLMGITGMATAECMNMGIKMGLEPKVLLDVLNNSSARSWSTEVYCPVPGLVPTAPS 333
+ NML I +A E + + + GL+ + SS S+ E +
Sbjct: 173 VITNMLAFIHLVAAGEALMLAKQGGLDLAQSYHAIVASSGNSFVHETESQL-------VL 225
Query: 332 SRNYDGGFKNELMVKDLELASGMALGIRSPIPLGA 228
+ +YD GF +L +KDL A GM P+ L +
Sbjct: 226 NGSYDIGFTMDLALKDLGFALGMGKDFGVPLELAS 260
>UniRef50_Q74D68 Cluster: 3-hydroxyisobutyrate dehydrogenase family
protein; n=7; Desulfuromonadales|Rep:
3-hydroxyisobutyrate dehydrogenase family protein -
Geobacter sulfurreducens
Length = 288
Score = 52.0 bits (119), Expect = 2e-05
Identities = 47/179 (26%), Positives = 71/179 (39%)
Frame = -3
Query: 680 FTXAPVXGGVMGAQNVTXAFMAGGXKEDFERSLXLLKVMGXKQFHCGQIGSGQVAKLTNN 501
F APV G A N +AGG R L G H G IG K N
Sbjct: 117 FLDAPVWGTKEHAANGLLTILAGGDPSLVGRCRELFSFFGLNIIHVGSIGDATRMKFVVN 176
Query: 500 MLMGITGMATAECMNMGIKMGLEPKVLLDVLNNSSARSWSTEVYCPVPGLVPTAPSSRNY 321
++ A AE + G K+G +L+VL++ S ++ + +RN
Sbjct: 177 LVQAELMQALAESIVFGEKLGFTADRILEVLDSGGVAS---PLFHSKGRSIARGDFTRNL 233
Query: 320 DGGFKNELMVKDLELASGMALGIRSPIPLGAVAXQLYRIVQSRGYGQKDFSFVFQLLKE 144
+ +E + LE A + L +P VA Y G G++DFS V ++L++
Sbjct: 234 ALKYVHEQLELVLEKAEKLGL----ELPAAKVACATYEQGVKDGRGEEDFSSVVKVLRK 288
>UniRef50_A6RMW8 Cluster: Putative uncharacterized protein; n=2;
Sclerotiniaceae|Rep: Putative uncharacterized protein -
Botryotinia fuckeliana B05.10
Length = 446
Score = 52.0 bits (119), Expect = 2e-05
Identities = 45/177 (25%), Positives = 72/177 (40%), Gaps = 1/177 (0%)
Frame = -3
Query: 695 RKGLGFTXAPVXGGVMGAQNVTXAFMAGGXKEDFERSLXLLKVMGXKQFHC-GQIGSGQV 519
RK + APV GG A T +A G ++ + + +L M G +G+G
Sbjct: 120 RKDVELVDAPVSGGTSRAALGTLVILASGPEKSLDAAKPVLDAMADPLHMIPGGLGAGTK 179
Query: 518 AKLTNNMLMGITGMATAECMNMGIKMGLEPKVLLDVLNNSSARSWSTEVYCPVPGLVPTA 339
K+ + L GI + +E M +GL K D L SS SW + VP
Sbjct: 180 VKMVHQALAGIHMIMASEAMGFAAFLGLNTKQAFDYLVKSSGESWM------LGNRVPHM 233
Query: 338 PSSRNYDGGFKNELMVKDLELASGMALGIRSPIPLGAVAXQLYRIVQSRGYGQKDFS 168
+ + N + VKD+ + + ++ P+ L + A Q+ G+G D S
Sbjct: 234 LENDLHPYSALN-IFVKDMGIVTADGRRVKCPLFLCSAAEQVLASGVRSGFGLDDDS 289
>UniRef50_A3JU55 Cluster: Predicted dehydrogenase, with
NAD(P)-binding Rossmann-fold domain; n=2; Bacteria|Rep:
Predicted dehydrogenase, with NAD(P)-binding
Rossmann-fold domain - Rhodobacterales bacterium
HTCC2150
Length = 302
Score = 51.6 bits (118), Expect = 3e-05
Identities = 43/168 (25%), Positives = 70/168 (41%), Gaps = 2/168 (1%)
Frame = -3
Query: 689 GLGFTXAPVXGGVMGAQNVTXAFMAGGXKEDFERSLXLLKVMGXKQFHCG-QIGSGQVAK 513
G+ PV GG GAQ T MA G E + +++ + + G + G GQ K
Sbjct: 112 GIHLIDTPVSGGFPGAQGGTLTMMAAGVDEVLDTYAPVMEAVSATIWCVGTEAGQGQTVK 171
Query: 512 LTNNMLMGITGMATAECMNMGIKMGLEPKVLLDVLNNSSARSWSTEVYCPVPGLVPTAPS 333
L+G AT E + K G+ +V +V+ NSS C +
Sbjct: 172 ACLQSLLGAMFSATFEASVLAAKAGINGEVFHNVVANSSGG-------CGITAGSLEKII 224
Query: 332 SRNYDG-GFKNELMVKDLELASGMALGIRSPIPLGAVAXQLYRIVQSR 192
R ++G G M KDL ++ G+ + P+ + A Q++ ++R
Sbjct: 225 DRQFEGTGSHIATMHKDLTISMGLGEQLGVPLHTASAAMQIFHAGKTR 272
>UniRef50_A7RG59 Cluster: Predicted protein; n=1; Nematostella
vectensis|Rep: Predicted protein - Nematostella
vectensis
Length = 341
Score = 51.6 bits (118), Expect = 3e-05
Identities = 48/185 (25%), Positives = 82/185 (44%), Gaps = 1/185 (0%)
Frame = -3
Query: 692 KGLGFTXAPVXGGVMGAQNVTXAFMAGGXKEDFERSLXLLKVMGXKQFHCGQIGSGQVAK 513
KG+ AP+ GG Q + F+ GG ++ + L+ + G +G VAK
Sbjct: 136 KGVHAVEAPLTGG----QGLMTVFV-GGEEKVVQDVKPLMDSYTATFLYFGPLGKATVAK 190
Query: 512 LTNNMLMGITGMATAECMNMGIKMGLEPKVLLDVLNNSSARSWSTEVYCPVPGLVPTAPS 333
+ +NML +A E + + K GL+ D + S+ S+ E P+
Sbjct: 191 VISNMLCAAHLVAAGEALMLAKKAGLDMSNFFDGIRYSAGNSYVFETEVPL-------MF 243
Query: 332 SRNYDGGFKNELMVKDLELASGMALGIRSPIPLGAVAXQLYRIVQSRGYGQK-DFSFVFQ 156
+ +YD F +L KDL L +A SP+ L + +YR + YG+ SF +
Sbjct: 244 NGSYDPDFTIDLHCKDLALGREIATSNDSPLELLGLTEDIYRRAMEK-YGKDVGSSFPAK 302
Query: 155 LLKEE 141
+L+++
Sbjct: 303 MLEDD 307
>UniRef50_Q5LQR0 Cluster: 6-phosphogluconate dehydrogenase domain
protein; n=14; Proteobacteria|Rep: 6-phosphogluconate
dehydrogenase domain protein - Silicibacter pomeroyi
Length = 302
Score = 51.2 bits (117), Expect = 3e-05
Identities = 29/95 (30%), Positives = 43/95 (45%)
Frame = -3
Query: 692 KGLGFTXAPVXGGVMGAQNVTXAFMAGGXKEDFERSLXLLKVMGXKQFHCGQIGSGQVAK 513
KG + AP+ A++ M G K F+R +L +G FH G +G+G K
Sbjct: 120 KGATYLDAPLGRTPAHARDGLLNIMCSGDKATFDRVKPVLHTLGENVFHLGALGNGHTIK 179
Query: 512 LTNNMLMGITGMATAECMNMGIKMGLEPKVLLDVL 408
L NN T A AE + G+E + L +V+
Sbjct: 180 LINNCYSMTTACAMAEAFAIADATGIERQALYNVM 214
>UniRef50_Q8UBW3 Cluster: Oxidoredutase; n=1; Agrobacterium
tumefaciens str. C58|Rep: Oxidoredutase - Agrobacterium
tumefaciens (strain C58 / ATCC 33970)
Length = 300
Score = 50.8 bits (116), Expect = 4e-05
Identities = 44/152 (28%), Positives = 67/152 (44%), Gaps = 2/152 (1%)
Frame = -3
Query: 689 GLGFTXAPVXGGVMGAQNVTXAFMAGGXKEDFERSLXLLKVMGXKQFHCGQIGSGQVAKL 510
G+ APV GGV GA T A MAGG + + + MG + + G G+GQ+ KL
Sbjct: 120 GIHHVDAPVSGGVPGATAGTLAIMAGGDEALISGLVDVFAPMG-RLTYVGPSGAGQLCKL 178
Query: 509 TNNMLMGITGMATAECMNMGIKMGLEPKVLLDVLNNSSARSWSTEVYCPVPGLVPTAPSS 330
N ++ IT A AE M + G + + + A S E++
Sbjct: 179 ANQQIVAITIGAVAEAMMLVEAGGASREGFRNAIRGGFAESRILELH-------GERMVK 231
Query: 329 RNYDGGFKNELMVKDLE--LASGMALGIRSPI 240
RN+ G ++ +KDL LA+ L + P+
Sbjct: 232 RNFVPGGPSKFQLKDLNGVLATAKDLALTLPL 263
>UniRef50_A0JRK4 Cluster: 6-phosphogluconate dehydrogenase,
NAD-binding precursor; n=3; Actinomycetales|Rep:
6-phosphogluconate dehydrogenase, NAD-binding precursor
- Arthrobacter sp. (strain FB24)
Length = 299
Score = 50.8 bits (116), Expect = 4e-05
Identities = 44/187 (23%), Positives = 77/187 (41%), Gaps = 1/187 (0%)
Frame = -3
Query: 689 GLGFTXAPVXGGVMGAQNVTXAFMAGGXKEDFERSLXLLKVMGXKQFHCG-QIGSGQVAK 513
G+ AP+ GG A + G E E++ L+++ G + G GQ K
Sbjct: 115 GVELVDAPLSGGPKRAGEGDLLIVVGASPEAQEKARPALELLASTLTVVGDKPGDGQALK 174
Query: 512 LTNNMLMGITGMATAECMNMGIKMGLEPKVLLDVLNNSSARSWSTEVYCPVPGLVPTAPS 333
N +L G+ A AE + + +GL+ + L L +A S+ P + A +
Sbjct: 175 TVNQLLCGVHIAAAAEALALADALGLDQEKTLKALEAGAAGSFMLSNRGP---RILEAYN 231
Query: 332 SRNYDGGFKNELMVKDLELASGMALGIRSPIPLGAVAXQLYRIVQSRGYGQKDFSFVFQL 153
+ + ++ VKD+ + P+ A A QLY + Q++G D S V ++
Sbjct: 232 EGGAEVLSRLDIFVKDMGIVGKATRAAGLAAPVAAAAEQLYLLGQAQGLAAADDSAVIKV 291
Query: 152 LKEENXN 132
+ N
Sbjct: 292 VAPTKRN 298
>UniRef50_A3H6C3 Cluster: 6-phosphogluconate dehydrogenase,
NAD-binding; n=1; Caldivirga maquilingensis IC-167|Rep:
6-phosphogluconate dehydrogenase, NAD-binding -
Caldivirga maquilingensis IC-167
Length = 284
Score = 50.8 bits (116), Expect = 4e-05
Identities = 43/182 (23%), Positives = 79/182 (43%)
Frame = -3
Query: 692 KGLGFTXAPVXGGVMGAQNVTXAFMAGGXKEDFERSLXLLKVMGXKQFHCGQIGSGQVAK 513
K L + + G A+ GG + F+ + +L +G + G K
Sbjct: 106 KRLRYLSVRLEKGPREAERGELVLYVGGDEGLFKEANSILSQIGTP-IYVGNHEQATALK 164
Query: 512 LTNNMLMGITGMATAECMNMGIKMGLEPKVLLDVLNNSSARSWSTEVYCPVPGLVPTAPS 333
L +N+++ + AE + K+G++P ++ L S S S ++ +P ++
Sbjct: 165 LISNVILTANTVVLAEVSVLIRKLGMDPDTVVKAL--SMGGSDSAQLRTRLPWML----- 217
Query: 332 SRNYDGGFKNELMVKDLELASGMALGIRSPIPLGAVAXQLYRIVQSRGYGQKDFSFVFQL 153
NY F L ++ A A I +P+ + +L RI ++ GYG KDFS + ++
Sbjct: 218 KGNYGESFSLRLARDVIDKALEYAQSIGIQLPMTTLIDELLRIAETTGYGSKDFSEIAEV 277
Query: 152 LK 147
LK
Sbjct: 278 LK 279
>UniRef50_Q6RXW5 Cluster: Succinic semialdehyde dehydrogenase; n=2;
Rhodococcus|Rep: Succinic semialdehyde dehydrogenase -
Rhodococcus sp. TK6
Length = 262
Score = 50.4 bits (115), Expect = 6e-05
Identities = 32/97 (32%), Positives = 49/97 (50%), Gaps = 1/97 (1%)
Frame = -3
Query: 671 APVXGGVMGAQNVTXA-FMAGGXKEDFERSLXLLKVMGXKQFHCGQIGSGQVAKLTNNML 495
APV GG GA++ + F+AG D E +L L+ + + F G + KL NN L
Sbjct: 115 APVSGGPQGARHGSMTVFLAGPAPTDAENAL--LEDISGRVFQMESYGQPALVKLLNNAL 172
Query: 494 MGITGMATAECMNMGIKMGLEPKVLLDVLNNSSARSW 384
ATA +N+ + G+ K L +V+ S+ +SW
Sbjct: 173 ATYNLAATARMLNLAAEHGVPAKDLFEVIGVSTGQSW 209
>UniRef50_A0VSV4 Cluster: 6-phosphogluconate dehydrogenase,
NAD-binding precursor; n=1; Dinoroseobacter shibae DFL
12|Rep: 6-phosphogluconate dehydrogenase, NAD-binding
precursor - Dinoroseobacter shibae DFL 12
Length = 289
Score = 50.4 bits (115), Expect = 6e-05
Identities = 48/172 (27%), Positives = 76/172 (44%), Gaps = 5/172 (2%)
Frame = -3
Query: 689 GLGFTXAPVXGGVMGAQNVTXAFMAGGXKEDFERSLXLLKVMGXKQFHCGQIGSGQVAKL 510
G F+ APV GG AQ+ + G F+ L+ G G+G AKL
Sbjct: 113 GAVFSDAPVTGGPKQAQDGALTSLVGCAAAQFDTIASLVGTYSTAIRRFGDAGTGHAAKL 172
Query: 509 TNNMLMGITGMATAECMNMGIKMGLEPKVLLDVLNNSSARSWSTEVYCPVPGLVPTAPSS 330
NN++ T + ++ ++G++P+ L +V+ +ARS + + P P L
Sbjct: 173 LNNLVTQGTMVLLSDAFQAAGRLGVDPRALYEVMMTGAARSGTLQKAVP-PAL------D 225
Query: 329 RNYDGG-FKNELMVKDLELASGM---ALGIRSPIPLGAVAXQLYRI-VQSRG 189
+Y G F KDL A + AL R+ + GA+A +L + Q RG
Sbjct: 226 GDYTGARFSISNAAKDLGYAEALLADALPGRADV-AGALAARLGALAAQGRG 276
>UniRef50_A0R1N5 Cluster: 6-phosphogluconate dehydrogenase,
NAD-binding; n=3; Mycobacterium|Rep: 6-phosphogluconate
dehydrogenase, NAD-binding - Mycobacterium smegmatis
(strain ATCC 700084 / mc(2)155)
Length = 263
Score = 50.4 bits (115), Expect = 6e-05
Identities = 30/102 (29%), Positives = 44/102 (43%)
Frame = -3
Query: 692 KGLGFTXAPVXGGVMGAQNVTXAFMAGGXKEDFERSLXLLKVMGXKQFHCGQIGSGQVAK 513
+G+ APV GG + AGG + ER L H G +GSGQ K
Sbjct: 109 RGVAVVDAPVSGGPHDIAAGSVTVFAGGDADVVERVRPALVAYAEPLLHVGPLGSGQRVK 168
Query: 512 LTNNMLMGITGMATAECMNMGIKMGLEPKVLLDVLNNSSARS 387
L NN + AE + + ++G++ +L L + SA S
Sbjct: 169 LVNNTMFAAQIGVVAEGVRLARELGVDEPTVLSALTHGSAAS 210
>UniRef50_O34969 Cluster: Uncharacterized oxidoreductase yfjR; n=1;
Bacillus subtilis|Rep: Uncharacterized oxidoreductase
yfjR - Bacillus subtilis
Length = 261
Score = 50.4 bits (115), Expect = 6e-05
Identities = 49/184 (26%), Positives = 80/184 (43%), Gaps = 2/184 (1%)
Frame = -3
Query: 692 KGLGFTXAPVXGGVMGAQNVTXAFMAGGXKEDFERSLXLLKVMGXKQFHCGQIG-SGQVA 516
KG F APV G A + G E + + LL + + F G+ + A
Sbjct: 86 KGQFFLAAPVLGRPDAAAKAALRIITAGPAEAKQAAKPLLDSLSQQIFDVGEESKTANAA 145
Query: 515 KLTNNMLMGITGMATAECMNMGIKMGLEPKVLLDVLNNSSARSWSTEVYCPVPGLVPTAP 336
K++ N L+ A +E M K GLE K L++ +SA S PV T
Sbjct: 146 KISINFLLVSMLEALSESFLMMEKYGLEQKQFLEI---ASALFGS-----PVYQNYGTIM 197
Query: 335 SSRNYD-GGFKNELMVKDLELASGMALGIRSPIPLGAVAXQLYRIVQSRGYGQKDFSFVF 159
+ + ++ GFK L +KD LA A + + +PL +A + +G+G D++ +
Sbjct: 198 AEQKFEPAGFKMSLGLKDTNLALAAAKRVSANLPLAELAKSHFESGIEKGFGDLDWAALI 257
Query: 158 QLLK 147
+ +K
Sbjct: 258 KCIK 261
>UniRef50_Q21AH6 Cluster: 6-phosphogluconate dehydrogenase,
NAD-binding; n=3; Bacteria|Rep: 6-phosphogluconate
dehydrogenase, NAD-binding - Rhodopseudomonas palustris
(strain BisB18)
Length = 292
Score = 50.0 bits (114), Expect = 8e-05
Identities = 39/148 (26%), Positives = 66/148 (44%), Gaps = 1/148 (0%)
Frame = -3
Query: 614 GGXKEDFERSLXLLKVMGXKQFHCGQIGSGQVAKLTNNMLMGITGMAT-AECMNMGIKMG 438
GG + E + K M F G + + KL +N L+G+T +A AE + K G
Sbjct: 140 GGDQVSLEALAPVFKHMSSVVFDMGSVEGATMFKLISN-LVGMTNLAILAEGYLLARKAG 198
Query: 437 LEPKVLLDVLNNSSARSWSTEVYCPVPGLVPTAPSSRNYDGGFKNELMVKDLELASGMAL 258
++P+V L + WST+ + ++ ++R F +L KDL L+ A
Sbjct: 199 IDPEVFSSALKTTGG--WSTQADIRLGWMINDDFTTR-----FAVDLAAKDLRLSVNAAA 251
Query: 257 GIRSPIPLGAVAXQLYRIVQSRGYGQKD 174
P P+ A ++ + ++ G G KD
Sbjct: 252 TWGIPTPVAAAGLSVFSLARAAGLGSKD 279
>UniRef50_A4FKN9 Cluster: 2-hydroxy-3-oxopropionate reductase; n=1;
Saccharopolyspora erythraea NRRL 2338|Rep:
2-hydroxy-3-oxopropionate reductase - Saccharopolyspora
erythraea (strain NRRL 23338)
Length = 297
Score = 49.6 bits (113), Expect = 1e-04
Identities = 40/182 (21%), Positives = 76/182 (41%)
Frame = -3
Query: 692 KGLGFTXAPVXGGVMGAQNVTXAFMAGGXKEDFERSLXLLKVMGXKQFHCGQIGSGQVAK 513
+G APV GG A+ + + M GG + D + +++ + CG G+GQ+AK
Sbjct: 116 RGCAVVDAPVSGGPTAARAGSLSVMVGGTEADVAAADEVIRAFAGRVVVCGGPGAGQIAK 175
Query: 512 LTNNMLMGITGMATAECMNMGIKMGLEPKVLLDVLNNSSARSWSTEVYCPVPGLVPTAPS 333
N +++ AE + +G +P + + L A S E++
Sbjct: 176 ACNQLVVTAGIAVVAEALVTASALGADPAAVREALLGGYAASRILELH-------GDRML 228
Query: 332 SRNYDGGFKNELMVKDLELASGMALGIRSPIPLGAVAXQLYRIVQSRGYGQKDFSFVFQL 153
R++ G +KD+ + + G+ A A + +V+S G G D S ++
Sbjct: 229 RRDFTLGAAARTQLKDIGIIRELTEGVVDNQVFEAAARAMEELVESGG-GDLDHSAAVRI 287
Query: 152 LK 147
++
Sbjct: 288 VE 289
>UniRef50_A4ECY9 Cluster: Putative uncharacterized protein; n=1;
Collinsella aerofaciens ATCC 25986|Rep: Putative
uncharacterized protein - Collinsella aerofaciens ATCC
25986
Length = 359
Score = 49.2 bits (112), Expect = 1e-04
Identities = 46/176 (26%), Positives = 69/176 (39%)
Frame = -3
Query: 668 PVXGGVMGAQNVTXAFMAGGXKEDFERSLXLLKVMGXKQFHCGQIGSGQVAKLTNNMLMG 489
PV GG GA T + G + D +L G GQ AKL N + +
Sbjct: 123 PVTGGESGAIAGTLTAIVGATENDIAPVRDVLSTFAANICCFDGAGKGQAAKLANQVSLA 182
Query: 488 ITGMATAECMNMGIKMGLEPKVLLDVLNNSSARSWSTEVYCPVPGLVPTAPSSRNYDGGF 309
+ A+ M GL+ + +++ + +S + E L P A +Y GF
Sbjct: 183 ACMVGMADAMAFAELSGLDLEKTREMILGGTGKSGAME------SLAPKALDG-DYKPGF 235
Query: 308 KNELMVKDLELASGMALGIRSPIPLGAVAXQLYRIVQSRGYGQKDFSFVFQLLKEE 141
E +KDL LA A +P VA LY ++ + G + + L KEE
Sbjct: 236 MVEHFIKDLRLALAYADDRELALPGADVAFTLYDMLDAIGGAKLGTQAITVLYKEE 291
>UniRef50_Q1V2K7 Cluster: NADP oxidoreductase, coenzyme
F420-dependent:6- phosphogluconatedehydrogenase,
NAD-binding:3-hydroxyacyl-CoA; n=1; Candidatus
Pelagibacter ubique HTCC1002|Rep: NADP oxidoreductase,
coenzyme F420-dependent:6-
phosphogluconatedehydrogenase,
NAD-binding:3-hydroxyacyl-CoA - Candidatus Pelagibacter
ubique HTCC1002
Length = 284
Score = 48.4 bits (110), Expect = 2e-04
Identities = 28/102 (27%), Positives = 45/102 (44%)
Frame = -3
Query: 692 KGLGFTXAPVXGGVMGAQNVTXAFMAGGXKEDFERSLXLLKVMGXKQFHCGQIGSGQVAK 513
K + + PV GG + A+ + GG +E+F+++ LK F+ G++G G +K
Sbjct: 111 KNINYIECPVMGGPVQAEEGVLGGIIGGSEENFKKAEVFLKAFCKDYFYFGEVGMGTKSK 170
Query: 512 LTNNMLMGITGMATAECMNMGIKMGLEPKVLLDVLNNSSARS 387
L NN L + K ++ K L DV S S
Sbjct: 171 LLNNFLTLGNATLIVHMIKGAKKFDIDLKKLYDVAKLGSGNS 212
>UniRef50_Q1GF31 Cluster: 6-phosphogluconate dehydrogenase
NAD-binding; n=17; Proteobacteria|Rep:
6-phosphogluconate dehydrogenase NAD-binding -
Silicibacter sp. (strain TM1040)
Length = 325
Score = 48.4 bits (110), Expect = 2e-04
Identities = 41/167 (24%), Positives = 69/167 (41%)
Frame = -3
Query: 668 PVXGGVMGAQNVTXAFMAGGXKEDFERSLXLLKVMGXKQFHCGQIGSGQVAKLTNNMLMG 489
PV GG A + AG + FER L L +G + H G IGS + K+ N L
Sbjct: 116 PVSGGCHRADTGNISIFAGCDRATFERMLPTLTTLGRRVLHTGDIGSASILKVMTNYLAT 175
Query: 488 ITGMATAECMNMGIKMGLEPKVLLDVLNNSSARSWSTEVYCPVPGLVPTAPSSRNYDGGF 309
+ E + G++ + + SS S+ E V SR D F
Sbjct: 176 ANLLTCCEALVTMKAAGIDLNTTYEAMKISSGTSFVHETESQV-----ILNGSR--DISF 228
Query: 308 KNELMVKDLELASGMALGIRSPIPLGAVAXQLYRIVQSRGYGQKDFS 168
+L+ KD+ L +A P+ + + +++ +R +G+++ S
Sbjct: 229 TMDLVKKDISLFQTIADAHGVPLEISPLLVEIFTDGIAR-FGERELS 274
>UniRef50_Q12H32 Cluster: 6-phosphogluconate dehydrogenase,
NAD-binding precursor; n=1; Polaromonas sp. JS666|Rep:
6-phosphogluconate dehydrogenase, NAD-binding precursor
- Polaromonas sp. (strain JS666 / ATCC BAA-500)
Length = 297
Score = 48.4 bits (110), Expect = 2e-04
Identities = 46/175 (26%), Positives = 72/175 (41%), Gaps = 3/175 (1%)
Frame = -3
Query: 692 KGLGFTXAPVXGGVMGAQNVTXAFMAGGXKEDFERSLXLLKVMGXKQFHCGQIGSGQVAK 513
+G+ AP+ + A+ M G + F++ +L FH G G+G V K
Sbjct: 113 RGVTLVDAPLARTPVEAELGRLNTMVGAEQAVFDKIRPVLAAYCENIFHVGGPGAGHVIK 172
Query: 512 LTNNMLMGITGMATAECMNMGIKMGLEPKVLLDVLNNSSARSWSTEVYCPVPGLVPTAPS 333
L NN + ATAE +G G+ P+ L++V++ + S GL
Sbjct: 173 LLNNFIGQAICTATAEAFAVGALAGINPQKLVEVISAGAVNS----------GLFQAMAK 222
Query: 332 SRNYD-GGFKNEL--MVKDLELASGMALGIRSPIPLGAVAXQLYRIVQSRGYGQK 177
+ N D G K EL KDL + +A + P +G Q + G G+K
Sbjct: 223 TLNGDFTGLKFELDNARKDLRYYTHLAEMVNVPSLVGEAVHQSLATASALGQGKK 277
>UniRef50_Q8T079 Cluster: LD22344p; n=2; Sophophora|Rep: LD22344p -
Drosophila melanogaster (Fruit fly)
Length = 602
Score = 48.4 bits (110), Expect = 2e-04
Identities = 37/176 (21%), Positives = 72/176 (40%), Gaps = 2/176 (1%)
Frame = -3
Query: 680 FTXAPVXGGVMGAQNVTXAFMAGGXKEDFERSLXLLKVMGXKQFHCGQIGSGQVAKLTNN 501
+ A + G A +AGG + FE K + F G IG+ L
Sbjct: 431 YLEAQIHGSRQEAAEGMLIILAGGDRSVFEECHSCFKTIAKNTFFLGNIGNACKVNLILQ 490
Query: 500 MLMGITGMATAECMNMGIKMGLEPKVLLDVLNNSSARSWSTEVYCPVPGLVPTAPSSRNY 321
++G++ + AE + + + + ++D+ + +S +S P L+
Sbjct: 491 TILGVSLVGLAEALALADRFSISLNDIIDIFDLTSMKS---------PMLLAKGKEMAKG 541
Query: 320 DGGFKNEL--MVKDLELASGMALGIRSPIPLGAVAXQLYRIVQSRGYGQKDFSFVF 159
D + L M +DL L MA + +P+ ++ ++++ + GY + D S VF
Sbjct: 542 DFNPQQPLSHMQRDLRLVLNMAENLDQSMPVTSITNEVFKHTKRLGYSEHDSSAVF 597
>UniRef50_P71825 Cluster: Uncharacterized oxidoreductase
Rv0770/MT0794; n=18; Corynebacterineae|Rep:
Uncharacterized oxidoreductase Rv0770/MT0794 -
Mycobacterium tuberculosis
Length = 295
Score = 48.4 bits (110), Expect = 2e-04
Identities = 44/165 (26%), Positives = 63/165 (38%), Gaps = 6/165 (3%)
Frame = -3
Query: 692 KGLGFTXAPVXGGVMGAQNVTXAFMAGGXKEDFERSLXLLKVMGXKQFHCGQIGSGQVAK 513
+G+ APV GG A A M G E F+R H G+ G+G K
Sbjct: 117 QGIHIVDAPVSGGAAAAAKGELAVMVGADDEAFQRIKEPFSRWASLLIHAGEPGAGTRMK 176
Query: 512 LTNNMLMGITGMATAECMNMGIKMGLEPKVLLDVLNNSSARSWST------EVYCPVPGL 351
L NML ++ A AE + GL+ L V+ +S + + P+
Sbjct: 177 LARNMLTFVSYAAAAEAQRLAEACGLDLVALGKVVRHSDSFTGGAGAIMFRNTTAPMEPA 236
Query: 350 VPTAPSSRNYDGGFKNELMVKDLELASGMALGIRSPIPLGAVAXQ 216
P P + G L KDL LA + + +PL +A Q
Sbjct: 237 DPLRPLLEHTRG-----LGEKDLSLALALGEVVSVDLPLAQLALQ 276
>UniRef50_Q8YRT5 Cluster: 3-hydroxyacid dehydrogenase; n=5;
Cyanobacteria|Rep: 3-hydroxyacid dehydrogenase -
Anabaena sp. (strain PCC 7120)
Length = 292
Score = 47.6 bits (108), Expect = 4e-04
Identities = 40/180 (22%), Positives = 70/180 (38%), Gaps = 1/180 (0%)
Frame = -3
Query: 680 FTXAPVXGGVMGAQNVTXAFMAGGXKEDFERSLXLLKVMGXKQFHCGQIGSGQVAKLTNN 501
+ APV G + AQ T M G + +ER L LLK G G +G+ KL N
Sbjct: 113 YIEAPVLGSIPEAQAGTLTVMVGAEPQQYERCLNLLKNFGPDPLLIGPVGTASGLKLALN 172
Query: 500 MLMGITGMATAECMNMGIKMGLEPKVLLDVLNNSSARSWSTEVYCPVPGLVPTAPSSRNY 321
L+ + A + + G++ + VL S+ +Y P NY
Sbjct: 173 QLIASLTTSFALSLAFVQRQGIDVDKFMQVLRESA-------LYAPTFDKKLQRMLDGNY 225
Query: 320 DG-GFKNELMVKDLELASGMALGIRSPIPLGAVAXQLYRIVQSRGYGQKDFSFVFQLLKE 144
F + ++KD +L A + + +L + + D+S +F ++++
Sbjct: 226 SNPNFPTKHLLKDTDLFISEAQYLGLDLSSIETVQKLLQTTMKMSFANDDYSALFSVIRD 285
>UniRef50_Q39KK8 Cluster: 6-phosphogluconate dehydrogenase,
NAD-binding; n=34; Bacteria|Rep: 6-phosphogluconate
dehydrogenase, NAD-binding - Burkholderia sp. (strain
383) (Burkholderia cepacia (strain ATCC 17760/ NCIB 9086
/ R18194))
Length = 289
Score = 47.6 bits (108), Expect = 4e-04
Identities = 44/177 (24%), Positives = 73/177 (41%), Gaps = 2/177 (1%)
Frame = -3
Query: 692 KGLGFTXAPVXGGVMGAQNVTXAFMAGGXKEDFERSLXLLKVMGXKQFHCGQIGS-GQVA 516
+G+ + APV G A MAGG E +R L +G K + G + VA
Sbjct: 108 RGIHYVAAPVMGRPDVAAAARLTIMAGGPAEAIDRVQPLFDAIGQKTWRFGSLPQHANVA 167
Query: 515 KLTNNMLMGITGMATAECMNMGIKMGLEPKVLLDVLNNSSARSWSTEVYCPVPGLVPTAP 336
K+ N + E + G+ + LDV+ S + VY ++
Sbjct: 168 KIAANFTLASAIETLGEASALLGAHGVAMRDFLDVITGS---VFPGPVYEGYGSMI---- 220
Query: 335 SSRNYD-GGFKNELMVKDLELASGMALGIRSPIPLGAVAXQLYRIVQSRGYGQKDFS 168
+ R+Y+ FK L +KD+ LA + P+P+ +V + G G++DF+
Sbjct: 221 AERHYEPARFKARLGLKDVRLALEAGDAVSVPLPVASVVRDNLLDALAHGGGEQDFA 277
>UniRef50_Q3W9L4 Cluster: Putative uncharacterized protein; n=1;
Frankia sp. EAN1pec|Rep: Putative uncharacterized
protein - Frankia sp. EAN1pec
Length = 294
Score = 47.6 bits (108), Expect = 4e-04
Identities = 28/100 (28%), Positives = 42/100 (42%)
Frame = -3
Query: 695 RKGLGFTXAPVXGGVMGAQNVTXAFMAGGXKEDFERSLXLLKVMGXKQFHCGQIGSGQVA 516
++ + APV GG A M GG + R +L+ H G +GSGQVA
Sbjct: 124 KQEISIIDAPVSGGGDAAAQRRLLVMVGGEDDAVARCRPVLETFACPVIHLGPLGSGQVA 183
Query: 515 KLTNNMLMGITGMATAECMNMGIKMGLEPKVLLDVLNNSS 396
KL NN + E + ++G++ VL + S
Sbjct: 184 KLVNNFVFTAQVGLALETFSFAQRLGMDRAAAAQVLAHGS 223
>UniRef50_A7H7Z5 Cluster: 6-phosphogluconate dehydrogenase
NAD-binding; n=2; Anaeromyxobacter|Rep:
6-phosphogluconate dehydrogenase NAD-binding -
Anaeromyxobacter sp. Fw109-5
Length = 293
Score = 47.6 bits (108), Expect = 4e-04
Identities = 44/183 (24%), Positives = 70/183 (38%)
Frame = -3
Query: 692 KGLGFTXAPVXGGVMGAQNVTXAFMAGGXKEDFERSLXLLKVMGXKQFHCGQIGSGQVAK 513
+G GF PV G A+ +AGG ER+ L + + F + K
Sbjct: 113 RGAGFVACPVLGSRSAAEQAQLVLVAGGPAVARERARPALHAVSARIFELEDAAQAALMK 172
Query: 512 LTNNMLMGITGMATAECMNMGIKMGLEPKVLLDVLNNSSARSWSTEVYCPVPGLVPTAPS 333
L N + G E + +G G+ L++VL A S+ + +Y LV
Sbjct: 173 LCVNAIGGAMITGFGEALALGQAGGVPVAKLVEVL---QASSFHSPLYLMKGELV----E 225
Query: 332 SRNYDGGFKNELMVKDLELASGMALGIRSPIPLGAVAXQLYRIVQSRGYGQKDFSFVFQL 153
R++ F L KD LA A + + P+ +++ G KD + V +L
Sbjct: 226 RRDWAPRFAIALAEKDQRLAQEAAADLGAKTPVNDTVRRVFADAAQSGRADKDIAAVAEL 285
Query: 152 LKE 144
E
Sbjct: 286 FFE 288
>UniRef50_A1UJF3 Cluster: 6-phosphogluconate dehydrogenase,
NAD-binding; n=4; Actinomycetales|Rep:
6-phosphogluconate dehydrogenase, NAD-binding -
Mycobacterium sp. (strain KMS)
Length = 272
Score = 47.6 bits (108), Expect = 4e-04
Identities = 29/101 (28%), Positives = 42/101 (41%)
Frame = -3
Query: 689 GLGFTXAPVXGGVMGAQNVTXAFMAGGXKEDFERSLXLLKVMGXKQFHCGQIGSGQVAKL 510
G+ APV GG GG + ER+ +L G H G +G+GQ KL
Sbjct: 112 GVDVVDAPVSGGPHDIAAGAVTLFVGGSEAAVERARPVLAAYGDPILHVGPLGAGQSVKL 171
Query: 509 TNNMLMGITGMATAECMNMGIKMGLEPKVLLDVLNNSSARS 387
NN + E + +G +G+ LL L + S+ S
Sbjct: 172 VNNTVFAAQIGLLREAVRLGGALGVAEPDLLTALTHGSSSS 212
>UniRef50_A3PRM1 Cluster: 6-phosphogluconate dehydrogenase,
NAD-binding precursor; n=2; Rhodobacter sphaeroides|Rep:
6-phosphogluconate dehydrogenase, NAD-binding precursor
- Rhodobacter sphaeroides (strain ATCC 17029 / ATH
2.4.9)
Length = 288
Score = 46.8 bits (106), Expect = 7e-04
Identities = 43/172 (25%), Positives = 71/172 (41%)
Frame = -3
Query: 689 GLGFTXAPVXGGVMGAQNVTXAFMAGGXKEDFERSLXLLKVMGXKQFHCGQIGSGQVAKL 510
G F PV G V A AGG E +R+ +L+ + + H G +G+ KL
Sbjct: 109 GAQFLHCPVGGTVAPALKGQLLGFAGGPAETLDRARPVLERLCRRVEHLGPVGAAARMKL 168
Query: 509 TNNMLMGITGMATAECMNMGIKMGLEPKVLLDVLNNSSARSWSTEVYCPVPGLVPTAPSS 330
N+ + + E + + G+ + + ++ SS + V +V T +
Sbjct: 169 AVNLPLALYWQTLGESLLLLRGAGVPAEQAIGLMAESSGGPAVLKNRAQV--VVETLEGA 226
Query: 329 RNYDGGFKNELMVKDLELASGMALGIRSPIPLGAVAXQLYRIVQSRGYGQKD 174
+ G F + KDL LA +A + +PL A A + YR G G+ D
Sbjct: 227 -DQRGTFDIAGLAKDLHLALALAEREGAALPLSAAAEERYRAALEAGLGRFD 277
>UniRef50_Q89M84 Cluster: Blr4309 protein; n=6;
Bradyrhizobiaceae|Rep: Blr4309 protein - Bradyrhizobium
japonicum
Length = 293
Score = 46.4 bits (105), Expect = 0.001
Identities = 30/102 (29%), Positives = 47/102 (46%)
Frame = -3
Query: 692 KGLGFTXAPVXGGVMGAQNVTXAFMAGGXKEDFERSLXLLKVMGXKQFHCGQIGSGQVAK 513
+GL + PV G A + G D ER+ L+ +G H G +GSG V K
Sbjct: 112 RGLIYIDCPVTGLPDAAAAGKLTLLVGADAADLERARPYLEPIGSTIRHFGAVGSGTVYK 171
Query: 512 LTNNMLMGITGMATAECMNMGIKMGLEPKVLLDVLNNSSARS 387
L NN++ I AE + + + GL+ ++L+ + A S
Sbjct: 172 LINNLMGAIQIAGLAEGLAIAEQAGLDMTLVLESIQAGVAAS 213
>UniRef50_Q5MZU3 Cluster: 3-hydroxyacid dehydrogenase; n=3;
Cyanobacteria|Rep: 3-hydroxyacid dehydrogenase -
Synechococcus sp. (strain ATCC 27144 / PCC 6301 / SAUG
1402/1)(Anacystis nidulans)
Length = 296
Score = 45.6 bits (103), Expect = 0.002
Identities = 47/184 (25%), Positives = 76/184 (41%), Gaps = 3/184 (1%)
Frame = -3
Query: 680 FTXAPVXGGVMGAQNVTXAFMAGGXKEDFERSLXLLKVMGXKQFHCGQIGSGQVAKLTNN 501
+ APV G + A+N T M G FE+ LL + + G IG+ KL N
Sbjct: 121 YLEAPVLGSLPEARNGTLIVMVGAEPAVFEQWRSLLCHLSPEPEWIGPIGTAATLKLALN 180
Query: 500 MLMGITGMATAECMNMGIKMGLEPKVLLDVLNNSSARSWSTEVYCPVPGLVPTAPSSRNY 321
L+G A + + + GL + + +L S+ +Y P + S Y
Sbjct: 181 QLIGSLTSAFGGSLALLQRSGLAVEPFMAILRQSA-------LYAPTFDKKLSRLLSHQY 233
Query: 320 DG-GFKNELMVKDLELASGMA--LGIRSPIPLGAVAXQLYRIVQSRGYGQKDFSFVFQLL 150
D F + KDL L A LGI + G + I Q G+G +D+S +++ +
Sbjct: 234 DNPNFPTTHLAKDLRLFRETAADLGITTDAVEGVESIVQKAIAQ--GWGDQDYSALYEAI 291
Query: 149 KEEN 138
++
Sbjct: 292 NPDS 295
>UniRef50_Q0RIL5 Cluster: Putative uncharacterized protein; n=1;
Frankia alni ACN14a|Rep: Putative uncharacterized
protein - Frankia alni (strain ACN14a)
Length = 493
Score = 45.2 bits (102), Expect = 0.002
Identities = 36/151 (23%), Positives = 62/151 (41%)
Frame = -3
Query: 686 LGFTXAPVXGGVMGAQNVTXAFMAGGXKEDFERSLXLLKVMGXKQFHCGQIGSGQVAKLT 507
+GF V G A + A + GG + E + +L + HCG +G+G V K+
Sbjct: 119 VGFLDCGVTPGDRAADHGMVAIV-GGDEATVEAARPVLDDWARRVVHCGPLGAGMVTKIA 177
Query: 506 NNMLMGITGMATAECMNMGIKMGLEPKVLLDVLNNSSARSWSTEVYCPVPGLVPTAPSSR 327
N++ + A E + G+ P L +V++ + + + G P +
Sbjct: 178 RNVVTYGSWRAVFEASALARAAGVNPARLAEVIDTADPEGHTLLTLLRLRGGDDRLPQAA 237
Query: 326 NYDGGFKNELMVKDLELASGMALGIRSPIPL 234
G LM KDL+ A +A + +PL
Sbjct: 238 ---GRKIQPLMTKDLDAARDLATALDVDVPL 265
>UniRef50_Q1B326 Cluster: 6-phosphogluconate dehydrogenase,
NAD-binding protein precursor; n=7; Bacteria|Rep:
6-phosphogluconate dehydrogenase, NAD-binding protein
precursor - Mycobacterium sp. (strain MCS)
Length = 299
Score = 44.4 bits (100), Expect = 0.004
Identities = 40/178 (22%), Positives = 77/178 (43%), Gaps = 2/178 (1%)
Frame = -3
Query: 689 GLGFTXAPVXGGVMGAQNVTXAFMAGGXKEDFERSLXLLKVMGXKQFHCG-QIGSGQVAK 513
G F APV G A +A G + E + + +G + F G + + + K
Sbjct: 114 GSRFVSAPVFGRPEAAAAAKLFVVAAGAPDTVEALAPVFEAIGQRTFVVGTEPKAANLVK 173
Query: 512 LTNNMLMGITGMATAECMNMGIKMGLEPKVLLDVLNNSSARSWSTEVYCPVPGLVPTAPS 333
++ N L+ + E M + K G++ LD+L ++ + Y GL+ +
Sbjct: 174 VSGNFLIASVIESLGEAMALVAKGGVDVDQYLDLLTSTL---FDAPAYRTYGGLL----A 226
Query: 332 SRNYD-GGFKNELMVKDLELASGMALGIRSPIPLGAVAXQLYRIVQSRGYGQKDFSFV 162
R ++ GF +KD+ LA G++ P+P+ ++ + + + G G D+S +
Sbjct: 227 RREFEPAGFSATGGLKDVRLALEAGDGLQVPLPIASLLRDRFLTLLATGGGHLDWSAI 284
>UniRef50_A5GJY3 Cluster: 3-hydroxyisobutyrate dehydrogenase related
protein; n=10; Synechococcus|Rep: 3-hydroxyisobutyrate
dehydrogenase related protein - Synechococcus sp.
(strain WH7803)
Length = 288
Score = 44.4 bits (100), Expect = 0.004
Identities = 38/136 (27%), Positives = 57/136 (41%), Gaps = 1/136 (0%)
Frame = -3
Query: 680 FTXAPVXGGVMGAQNVTXAFMAGGXKEDFERSLXLLKVMGXKQFHCGQIGSGQVAKLTNN 501
+ APV G A T MAGG + F++ LLK + + G +G+G AKL N
Sbjct: 111 YLEAPVLGSRPEALAGTLLVMAGGDQGVFDQQYALLKHLALEPKRMGAVGTGAAAKLALN 170
Query: 500 MLMGITGMATAECMNMGIKMGLEPKVLLDVLNNSSARSWSTEVYCPVPGLVPTAPSSRNY 321
L+ + + + GL+ +DVL S+ +Y P + +Y
Sbjct: 171 QLIASLTHGYSLALRLIQASGLDVDSFMDVLRPSA-------LYAPTVDKKLKRMLTHDY 223
Query: 320 -DGGFKNELMVKDLEL 276
D F L+ KDL L
Sbjct: 224 SDPNFSTSLLRKDLNL 239
>UniRef50_UPI0000F1E276 Cluster: PREDICTED: similar to G
protein-coupled receptor 155; n=1; Danio rerio|Rep:
PREDICTED: similar to G protein-coupled receptor 155 -
Danio rerio
Length = 380
Score = 43.6 bits (98), Expect = 0.007
Identities = 38/120 (31%), Positives = 57/120 (47%)
Frame = -3
Query: 563 GXKQFHCGQIGSGQVAKLTNNMLMGITGMATAECMNMGIKMGLEPKVLLDVLNNSSARSW 384
G F+ G GQ++KLT + + + + TA+ + M + M + LLD N+SSA
Sbjct: 54 GAALFYLGLNMVGQMSKLTRSTGVSLILLITAKLLVMPL-MCRDMVELLDAGNSSSANHS 112
Query: 383 STEVYCPVPGLVPTAPSSRNYDGGFKNELMVKDLELASGMALGIRSPIPLGAVAXQLYRI 204
S Y + G+ PTAPS Y + EL V + SGM + P+ V+ L I
Sbjct: 113 SLSDYAFLYGVFPTAPSVAIYAAQYNMELEV----VTSGMVISTFLSAPIMYVSAWLLTI 168
>UniRef50_A3Q3U7 Cluster: 6-phosphogluconate dehydrogenase,
NAD-binding; n=3; Mycobacterium|Rep: 6-phosphogluconate
dehydrogenase, NAD-binding - Mycobacterium sp. (strain
JLS)
Length = 279
Score = 43.2 bits (97), Expect = 0.009
Identities = 27/95 (28%), Positives = 38/95 (40%)
Frame = -3
Query: 671 APVXGGVMGAQNVTXAFMAGGXKEDFERSLXLLKVMGXKQFHCGQIGSGQVAKLTNNMLM 492
APV G T + GG + +L G +GS KL NN+L
Sbjct: 119 APVSGTADDIAAGTLTVLLGGPADAVAAVTPVLAAYADPLVPTGTLGSALALKLINNLLF 178
Query: 491 GITGMATAECMNMGIKMGLEPKVLLDVLNNSSARS 387
A +G ++G++P+VLL L SA S
Sbjct: 179 AANAQLLAAATELGTQLGVDPEVLLSTLQVCSAGS 213
>UniRef50_A0FZ97 Cluster: 6-phosphogluconate dehydrogenase,
NAD-binding; n=1; Burkholderia phymatum STM815|Rep:
6-phosphogluconate dehydrogenase, NAD-binding -
Burkholderia phymatum STM815
Length = 293
Score = 43.2 bits (97), Expect = 0.009
Identities = 39/157 (24%), Positives = 63/157 (40%), Gaps = 1/157 (0%)
Frame = -3
Query: 689 GLGFTXAPVXGGVMGAQNVTXAFMAGGXKEDFERSLXLLKVMGXKQFHCGQIGSGQVAKL 510
G+ AP+ T A GG + +L+ + HCG GSG +L
Sbjct: 109 GITLVDAPLHTENTATAPETSAIFFGGPSSVLASTREILENVCPTIIHCGDAGSGHAMRL 168
Query: 509 TNNMLMGITGMATAECMNMGIKMGLEPKVLLDVLNNSSA-RSWSTEVYCPVPGLVPTAPS 333
+ + T EC MG + GL + VLN SS S S V +P + +
Sbjct: 169 VVAAIAACNRLITYECAAMGARNGLTIGDMATVLNKSSGYNSASARV---LPAMTANKRT 225
Query: 332 SRNYDGGFKNELMVKDLELASGMALGIRSPIPLGAVA 222
+ G + + DL AS +A+ + +P+ + +A
Sbjct: 226 ANVTLGAWAD-----DLRKASSVAMRLGAPMLIATMA 257
>UniRef50_A3ES45 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=1;
Leptospirillum sp. Group II UBA|Rep:
3-hydroxyisobutyrate dehydrogenase - Leptospirillum sp.
Group II UBA
Length = 307
Score = 42.3 bits (95), Expect = 0.016
Identities = 46/186 (24%), Positives = 80/186 (43%), Gaps = 2/186 (1%)
Frame = -3
Query: 692 KGLGFTXAPVXGGVMGAQNVTXAFMAGGXKEDFERSLXLLKVMGXKQFHCGQIGS--GQV 519
+G APV G A+ T +A G ++ E L LL+ +G F G+ S +
Sbjct: 122 RGQILVSAPVFGRPDRAEAGTLTIVAAGPQKTLESLLPLLEHLGSPVFCVGEDPSLANHI 181
Query: 518 AKLTNNMLMGITGMATAECMNMGIKMGLEPKVLLDVLNNSSARSWSTEVYCPVPGLVPTA 339
L N L G+ AE +++ ++G+ P L+++L+ + RS Y +
Sbjct: 182 KVLGNFTLAGLLE-TLAESLSLARRVGVSPGQLVEILDTALYRSPVFRNYGQLMAREDFQ 240
Query: 338 PSSRNYDGGFKNELMVKDLELASGMALGIRSPIPLGAVAXQLYRIVQSRGYGQKDFSFVF 159
P+ GF+ L +KD+ L A + +PL + + RG D+S +
Sbjct: 241 PA------GFRMRLGLKDVRLVQKEADRVDVALPLADLLHAGFLAGIHRGMEDWDWSALG 294
Query: 158 QLLKEE 141
Q+ E+
Sbjct: 295 QVRAED 300
>UniRef50_Q9K9H3 Cluster: 6-phosphogluconate dehydrogenase; n=7;
Firmicutes|Rep: 6-phosphogluconate dehydrogenase -
Bacillus halodurans
Length = 298
Score = 41.9 bits (94), Expect = 0.021
Identities = 35/112 (31%), Positives = 50/112 (44%), Gaps = 5/112 (4%)
Frame = -3
Query: 692 KGLGFTXAPVXGGVMGAQNVTXAFMAGGXKEDFERSLXLLKVMGXKQ--FHCGQIGSGQV 519
KGL F A GG+ GA+ M GG KE E LLK + + + G +GSG
Sbjct: 111 KGLHFVDAGTSGGIDGARE-GACLMVGGTKEVVESLAPLLKEIAVEDGYLYTGPVGSGHF 169
Query: 518 AKLTNNMLMGITGMATAECMNM--GIKMGLEPKVLLDVLNNSSA-RSWSTEV 372
K+ +N + A AE ++ + + + V NN S RSW E+
Sbjct: 170 LKMIHNGIEYGMMQAIAEGFDLLENSPFDYDYEAVAKVWNNGSVIRSWLMEL 221
>UniRef50_Q2JEN4 Cluster: 6-phosphogluconate dehydrogenase,
NAD-binding; n=1; Frankia sp. CcI3|Rep:
6-phosphogluconate dehydrogenase, NAD-binding - Frankia
sp. (strain CcI3)
Length = 290
Score = 41.9 bits (94), Expect = 0.021
Identities = 40/174 (22%), Positives = 73/174 (41%), Gaps = 2/174 (1%)
Frame = -3
Query: 689 GLGFTXAPVXGGVMGAQNVTXAFMAGGXKEDFERSLXLLKVMGXKQFHCGQIGS-GQVAK 513
GL + APV G A+ + G + L V+G + + G + K
Sbjct: 109 GLRYLAAPVFGRTDAARAGNLTIVTSGDPDTIAEVQPLFDVLGRRTWTVGDAPEHANLVK 168
Query: 512 LTNNMLMGITGMATAECMNMGIKMGLEPKVLLDVLNNSSARSWSTEVYCPVPGLVPTAPS 333
+ N L+ + A AE + G+ P ++VL ++ ++ V+ ++
Sbjct: 169 ILGNYLIACSIEAMAEASAVIEAGGMNPATFIEVLTDNL---FTGPVFTGYGRMI----G 221
Query: 332 SRNYDG-GFKNELMVKDLELASGMALGIRSPIPLGAVAXQLYRIVQSRGYGQKD 174
+R+Y+ F+ L +KD++LA L P+P G V + V + +GQ D
Sbjct: 222 NRDYEPVNFRLPLGLKDVQLALASGLERNVPLPFGGVLRDAF--VDALAHGQTD 273
Database: uniref50
Posted date: Oct 5, 2007 11:19 AM
Number of letters in database: 575,637,011
Number of sequences in database: 1,657,284
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 797,151,276
Number of Sequences: 1657284
Number of extensions: 15801851
Number of successful extensions: 38928
Number of sequences better than 10.0: 275
Number of HSP's better than 10.0 without gapping: 36946
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 38705
length of database: 575,637,011
effective HSP length: 100
effective length of database: 409,908,611
effective search space used: 79112361923
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
- SilkBase 1999-2023 -