Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= MFBP05_F_L13
(895 letters)
Database: human
237,096 sequences; 76,859,062 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
BC005288-1|AAH05288.1| 260|Homo sapiens TGF beta-inducible nucl... 214 3e-55
AY443419-1|AAS00024.1| 260|Homo sapiens TGF-beta inducible nucl... 214 3e-55
AJ012409-1|CAA10008.1| 260|Homo sapiens hypothetical protein pr... 214 3e-55
AF372458-1|AAK53761.1| 260|Homo sapiens hairy cell leukemia pro... 214 3e-55
AF077615-1|AAG43048.1| 260|Homo sapiens TGF beta inducible nucl... 214 3e-55
BC011571-1|AAH11571.1| 903|Homo sapiens ITCH protein protein. 31 5.6
AL356299-4|CAI17959.1| 903|Homo sapiens itchy homolog E3 ubiqui... 31 5.6
AL356299-3|CAI17960.1| 862|Homo sapiens itchy homolog E3 ubiqui... 31 5.6
AL109923-6|CAI21458.1| 903|Homo sapiens itchy homolog E3 ubiqui... 31 5.6
AL109923-5|CAI21459.1| 862|Homo sapiens itchy homolog E3 ubiqui... 31 5.6
AF095745-1|AAK39399.1| 862|Homo sapiens ubiquitin protein ligas... 31 5.6
AB056663-1|BAB39389.1| 862|Homo sapiens ubiquitin protein ligas... 31 5.6
>BC005288-1|AAH05288.1| 260|Homo sapiens TGF beta-inducible nuclear
protein 1 protein.
Length = 260
Score = 214 bits (523), Expect = 3e-55
Identities = 103/145 (71%), Positives = 114/145 (78%)
Frame = +1
Query: 379 QSRAKVLSNMIKQKRKEKAGKWDVPIPKVRAQADAEVFKVLKSGKSKRKAWKRMVTKVTF 558
QSRAKVLSNMIKQKRKEKAGKW+VP+PKVRAQ + EV KV+++GK K+KAWKRMVTKV F
Sbjct: 96 QSRAKVLSNMIKQKRKEKAGKWEVPLPKVRAQGETEVLKVIRTGKRKKKAWKRMVTKVCF 155
Query: 559 VGENFTRKPPKFERFIRPMALRFKKAHVTHPELKATFCLPIIGVKKNPKFTNVYKLRCHN 738
VG+ FTRKPPK+ERFIRPM LRFKKAHVTHPELKATFCLPI+GVKKNP L
Sbjct: 156 VGDGFTRKPPKYERFIRPMGLRFKKAHVTHPELKATFCLPILGVKKNPSSPLYTTLGVIT 215
Query: 739 *GYSDXS*YF*AGSVTQAGKVVWGK 813
G G VTQ GKV+WGK
Sbjct: 216 KGTVIEVNVSELGLVTQGGKVIWGK 240
Score = 74.5 bits (175), Expect = 5e-13
Identities = 38/84 (45%), Positives = 49/84 (58%), Gaps = 1/84 (1%)
Frame = +3
Query: 123 HQKLYGSRLAYXXXXXXXXXXXXXXXXXXXXXLRGIKAKIFNKERRNEKIQMKKKIKAHE 302
H+K YG RL Y + G+KAK+++K+R EKIQMKK IK HE
Sbjct: 10 HRKRYGYRLDYHEKKRKKESREAHERSKKAKKMIGLKAKLYHKQRHAEKIQMKKTIKMHE 69
Query: 303 EKNVKQ-NTEKVAEGALPVYLLDR 371
++N KQ N EK +GA+P YLLDR
Sbjct: 70 KRNTKQKNDEKTPQGAVPAYLLDR 93
>AY443419-1|AAS00024.1| 260|Homo sapiens TGF-beta inducible nuclear
protein protein.
Length = 260
Score = 214 bits (523), Expect = 3e-55
Identities = 103/145 (71%), Positives = 114/145 (78%)
Frame = +1
Query: 379 QSRAKVLSNMIKQKRKEKAGKWDVPIPKVRAQADAEVFKVLKSGKSKRKAWKRMVTKVTF 558
QSRAKVLSNMIKQKRKEKAGKW+VP+PKVRAQ + EV KV+++GK K+KAWKRMVTKV F
Sbjct: 96 QSRAKVLSNMIKQKRKEKAGKWEVPLPKVRAQGETEVLKVIRTGKRKKKAWKRMVTKVCF 155
Query: 559 VGENFTRKPPKFERFIRPMALRFKKAHVTHPELKATFCLPIIGVKKNPKFTNVYKLRCHN 738
VG+ FTRKPPK+ERFIRPM LRFKKAHVTHPELKATFCLPI+GVKKNP L
Sbjct: 156 VGDGFTRKPPKYERFIRPMGLRFKKAHVTHPELKATFCLPILGVKKNPSSPLYTTLGVIT 215
Query: 739 *GYSDXS*YF*AGSVTQAGKVVWGK 813
G G VTQ GKV+WGK
Sbjct: 216 KGTVIEVNVSELGLVTQGGKVIWGK 240
Score = 74.5 bits (175), Expect = 5e-13
Identities = 38/84 (45%), Positives = 49/84 (58%), Gaps = 1/84 (1%)
Frame = +3
Query: 123 HQKLYGSRLAYXXXXXXXXXXXXXXXXXXXXXLRGIKAKIFNKERRNEKIQMKKKIKAHE 302
H+K YG RL Y + G+KAK+++K+R EKIQMKK IK HE
Sbjct: 10 HRKRYGYRLDYHEKKRKKESREAHERSKKAKKMIGLKAKLYHKQRHAEKIQMKKTIKMHE 69
Query: 303 EKNVKQ-NTEKVAEGALPVYLLDR 371
++N KQ N EK +GA+P YLLDR
Sbjct: 70 KRNTKQKNDEKTPQGAVPAYLLDR 93
>AJ012409-1|CAA10008.1| 260|Homo sapiens hypothetical protein
protein.
Length = 260
Score = 214 bits (523), Expect = 3e-55
Identities = 103/145 (71%), Positives = 114/145 (78%)
Frame = +1
Query: 379 QSRAKVLSNMIKQKRKEKAGKWDVPIPKVRAQADAEVFKVLKSGKSKRKAWKRMVTKVTF 558
QSRAKVLSNMIKQKRKEKAGKW+VP+PKVRAQ + EV KV+++GK K+KAWKRMVTKV F
Sbjct: 96 QSRAKVLSNMIKQKRKEKAGKWEVPLPKVRAQGETEVLKVIRTGKRKKKAWKRMVTKVCF 155
Query: 559 VGENFTRKPPKFERFIRPMALRFKKAHVTHPELKATFCLPIIGVKKNPKFTNVYKLRCHN 738
VG+ FTRKPPK+ERFIRPM LRFKKAHVTHPELKATFCLPI+GVKKNP L
Sbjct: 156 VGDGFTRKPPKYERFIRPMGLRFKKAHVTHPELKATFCLPILGVKKNPSSPLYTTLGVIT 215
Query: 739 *GYSDXS*YF*AGSVTQAGKVVWGK 813
G G VTQ GKV+WGK
Sbjct: 216 KGTVIEVNVSELGLVTQGGKVIWGK 240
Score = 74.5 bits (175), Expect = 5e-13
Identities = 38/84 (45%), Positives = 49/84 (58%), Gaps = 1/84 (1%)
Frame = +3
Query: 123 HQKLYGSRLAYXXXXXXXXXXXXXXXXXXXXXLRGIKAKIFNKERRNEKIQMKKKIKAHE 302
H+K YG RL Y + G+KAK+++K+R EKIQMKK IK HE
Sbjct: 10 HRKRYGYRLDYHEKKRKKESREAHERSKKAKKMIGLKAKLYHKQRHAEKIQMKKTIKMHE 69
Query: 303 EKNVKQ-NTEKVAEGALPVYLLDR 371
++N KQ N EK +GA+P YLLDR
Sbjct: 70 KRNTKQKNDEKTPQGAVPAYLLDR 93
>AF372458-1|AAK53761.1| 260|Homo sapiens hairy cell leukemia
protein 1 protein.
Length = 260
Score = 214 bits (523), Expect = 3e-55
Identities = 103/145 (71%), Positives = 114/145 (78%)
Frame = +1
Query: 379 QSRAKVLSNMIKQKRKEKAGKWDVPIPKVRAQADAEVFKVLKSGKSKRKAWKRMVTKVTF 558
QSRAKVLSNMIKQKRKEKAGKW+VP+PKVRAQ + EV KV+++GK K+KAWKRMVTKV F
Sbjct: 96 QSRAKVLSNMIKQKRKEKAGKWEVPLPKVRAQGETEVLKVIRTGKRKKKAWKRMVTKVCF 155
Query: 559 VGENFTRKPPKFERFIRPMALRFKKAHVTHPELKATFCLPIIGVKKNPKFTNVYKLRCHN 738
VG+ FTRKPPK+ERFIRPM LRFKKAHVTHPELKATFCLPI+GVKKNP L
Sbjct: 156 VGDGFTRKPPKYERFIRPMGLRFKKAHVTHPELKATFCLPILGVKKNPSSPLYTTLGVIT 215
Query: 739 *GYSDXS*YF*AGSVTQAGKVVWGK 813
G G VTQ GKV+WGK
Sbjct: 216 KGTVIEVNVSELGLVTQGGKVIWGK 240
Score = 74.5 bits (175), Expect = 5e-13
Identities = 38/84 (45%), Positives = 49/84 (58%), Gaps = 1/84 (1%)
Frame = +3
Query: 123 HQKLYGSRLAYXXXXXXXXXXXXXXXXXXXXXLRGIKAKIFNKERRNEKIQMKKKIKAHE 302
H+K YG RL Y + G+KAK+++K+R EKIQMKK IK HE
Sbjct: 10 HRKRYGYRLDYHEKKRKKESREAHERSKKAKKMIGLKAKLYHKQRHAEKIQMKKTIKMHE 69
Query: 303 EKNVKQ-NTEKVAEGALPVYLLDR 371
++N KQ N EK +GA+P YLLDR
Sbjct: 70 KRNTKQKNDEKTPQGAVPAYLLDR 93
>AF077615-1|AAG43048.1| 260|Homo sapiens TGF beta inducible nuclear
protein TINP1 protein.
Length = 260
Score = 214 bits (523), Expect = 3e-55
Identities = 103/145 (71%), Positives = 114/145 (78%)
Frame = +1
Query: 379 QSRAKVLSNMIKQKRKEKAGKWDVPIPKVRAQADAEVFKVLKSGKSKRKAWKRMVTKVTF 558
QSRAKVLSNMIKQKRKEKAGKW+VP+PKVRAQ + EV KV+++GK K+KAWKRMVTKV F
Sbjct: 96 QSRAKVLSNMIKQKRKEKAGKWEVPLPKVRAQGETEVLKVIRTGKRKKKAWKRMVTKVCF 155
Query: 559 VGENFTRKPPKFERFIRPMALRFKKAHVTHPELKATFCLPIIGVKKNPKFTNVYKLRCHN 738
VG+ FTRKPPK+ERFIRPM LRFKKAHVTHPELKATFCLPI+GVKKNP L
Sbjct: 156 VGDGFTRKPPKYERFIRPMGLRFKKAHVTHPELKATFCLPILGVKKNPSSPLYTTLGVIT 215
Query: 739 *GYSDXS*YF*AGSVTQAGKVVWGK 813
G G VTQ GKV+WGK
Sbjct: 216 KGTVIEVNVSELGLVTQGGKVIWGK 240
Score = 74.5 bits (175), Expect = 5e-13
Identities = 38/84 (45%), Positives = 49/84 (58%), Gaps = 1/84 (1%)
Frame = +3
Query: 123 HQKLYGSRLAYXXXXXXXXXXXXXXXXXXXXXLRGIKAKIFNKERRNEKIQMKKKIKAHE 302
H+K YG RL Y + G+KAK+++K+R EKIQMKK IK HE
Sbjct: 10 HRKRYGYRLDYHEKKRKKESREAHERSKKAKKMIGLKAKLYHKQRHAEKIQMKKTIKMHE 69
Query: 303 EKNVKQ-NTEKVAEGALPVYLLDR 371
++N KQ N EK +GA+P YLLDR
Sbjct: 70 KRNTKQKNDEKTPQGAVPAYLLDR 93
>BC011571-1|AAH11571.1| 903|Homo sapiens ITCH protein protein.
Length = 903
Score = 31.1 bits (67), Expect = 5.6
Identities = 15/61 (24%), Positives = 26/61 (42%)
Frame = +1
Query: 370 GDVQSRAKVLSNMIKQKRKEKAGKWDVPIPKVRAQADAEVFKVLKSGKSKRKAWKRMVTK 549
G + ++++ +I K KE W P P V D + K K + WK+ +T
Sbjct: 12 GSLTMKSQLQITVISAKLKENKKNWFGPSPYVEVTVDGQSKKTEKCNNTNSPKWKQPLTV 71
Query: 550 V 552
+
Sbjct: 72 I 72
>AL356299-4|CAI17959.1| 903|Homo sapiens itchy homolog E3 ubiquitin
protein ligase (mouse) protein.
Length = 903
Score = 31.1 bits (67), Expect = 5.6
Identities = 15/61 (24%), Positives = 26/61 (42%)
Frame = +1
Query: 370 GDVQSRAKVLSNMIKQKRKEKAGKWDVPIPKVRAQADAEVFKVLKSGKSKRKAWKRMVTK 549
G + ++++ +I K KE W P P V D + K K + WK+ +T
Sbjct: 12 GSLTMKSQLQITVISAKLKENKKNWFGPSPYVEVTVDGQSKKTEKCNNTNSPKWKQPLTV 71
Query: 550 V 552
+
Sbjct: 72 I 72
>AL356299-3|CAI17960.1| 862|Homo sapiens itchy homolog E3 ubiquitin
protein ligase (mouse) protein.
Length = 862
Score = 31.1 bits (67), Expect = 5.6
Identities = 15/61 (24%), Positives = 26/61 (42%)
Frame = +1
Query: 370 GDVQSRAKVLSNMIKQKRKEKAGKWDVPIPKVRAQADAEVFKVLKSGKSKRKAWKRMVTK 549
G + ++++ +I K KE W P P V D + K K + WK+ +T
Sbjct: 12 GSLTMKSQLQITVISAKLKENKKNWFGPSPYVEVTVDGQSKKTEKCNNTNSPKWKQPLTV 71
Query: 550 V 552
+
Sbjct: 72 I 72
>AL109923-6|CAI21458.1| 903|Homo sapiens itchy homolog E3 ubiquitin
protein ligase (mouse) protein.
Length = 903
Score = 31.1 bits (67), Expect = 5.6
Identities = 15/61 (24%), Positives = 26/61 (42%)
Frame = +1
Query: 370 GDVQSRAKVLSNMIKQKRKEKAGKWDVPIPKVRAQADAEVFKVLKSGKSKRKAWKRMVTK 549
G + ++++ +I K KE W P P V D + K K + WK+ +T
Sbjct: 12 GSLTMKSQLQITVISAKLKENKKNWFGPSPYVEVTVDGQSKKTEKCNNTNSPKWKQPLTV 71
Query: 550 V 552
+
Sbjct: 72 I 72
>AL109923-5|CAI21459.1| 862|Homo sapiens itchy homolog E3 ubiquitin
protein ligase (mouse) protein.
Length = 862
Score = 31.1 bits (67), Expect = 5.6
Identities = 15/61 (24%), Positives = 26/61 (42%)
Frame = +1
Query: 370 GDVQSRAKVLSNMIKQKRKEKAGKWDVPIPKVRAQADAEVFKVLKSGKSKRKAWKRMVTK 549
G + ++++ +I K KE W P P V D + K K + WK+ +T
Sbjct: 12 GSLTMKSQLQITVISAKLKENKKNWFGPSPYVEVTVDGQSKKTEKCNNTNSPKWKQPLTV 71
Query: 550 V 552
+
Sbjct: 72 I 72
>AF095745-1|AAK39399.1| 862|Homo sapiens ubiquitin protein ligase
ITCH protein.
Length = 862
Score = 31.1 bits (67), Expect = 5.6
Identities = 15/61 (24%), Positives = 26/61 (42%)
Frame = +1
Query: 370 GDVQSRAKVLSNMIKQKRKEKAGKWDVPIPKVRAQADAEVFKVLKSGKSKRKAWKRMVTK 549
G + ++++ +I K KE W P P V D + K K + WK+ +T
Sbjct: 12 GSLTMKSQLQITVISAKLKENKKNWFGPSPYVEVTVDGQSKKTEKCNNTNSPKWKQPLTV 71
Query: 550 V 552
+
Sbjct: 72 I 72
>AB056663-1|BAB39389.1| 862|Homo sapiens ubiquitin protein ligase
Itch protein.
Length = 862
Score = 31.1 bits (67), Expect = 5.6
Identities = 15/61 (24%), Positives = 26/61 (42%)
Frame = +1
Query: 370 GDVQSRAKVLSNMIKQKRKEKAGKWDVPIPKVRAQADAEVFKVLKSGKSKRKAWKRMVTK 549
G + ++++ +I K KE W P P V D + K K + WK+ +T
Sbjct: 12 GSLTMKSQLQITVISAKLKENKKNWFGPSPYVEVTVDGQSKKTEKCNNTNSPKWKQPLTV 71
Query: 550 V 552
+
Sbjct: 72 I 72
Database: human
Posted date: Oct 23, 2007 1:18 PM
Number of letters in database: 76,859,062
Number of sequences in database: 237,096
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 105,193,220
Number of Sequences: 237096
Number of extensions: 2041365
Number of successful extensions: 4818
Number of sequences better than 10.0: 12
Number of HSP's better than 10.0 without gapping: 4617
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 4799
length of database: 76,859,062
effective HSP length: 90
effective length of database: 55,520,422
effective search space used: 11492727354
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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