BLASTX 2.2.12 [Aug-07-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= MFBP04_F_E02 (887 letters) Database: uniref50 1,657,284 sequences; 575,637,011 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value UniRef50_Q7PCV3 Cluster: ENSANGP00000031808; n=9; Endopterygota|... 150 5e-35 UniRef50_UPI0000D56CE5 Cluster: PREDICTED: similar to CG6084-PA,... 144 4e-33 UniRef50_Q2LZ66 Cluster: GA19341-PA; n=2; Endopterygota|Rep: GA1... 139 8e-32 UniRef50_P45376 Cluster: Aldose reductase; n=21; Bilateria|Rep: ... 138 2e-31 UniRef50_UPI00015B56A2 Cluster: PREDICTED: similar to GA10458-PA... 135 2e-30 UniRef50_P15121 Cluster: Aldose reductase; n=72; Eumetazoa|Rep: ... 134 3e-30 UniRef50_Q9VTL0 Cluster: CG6083-PA; n=4; Diptera|Rep: CG6083-PA ... 132 2e-29 UniRef50_Q8CI22 Cluster: 2310005E10Rik protein; n=30; Tetrapoda|... 130 5e-29 UniRef50_Q9NAI5 Cluster: Putative uncharacterized protein; n=3; ... 128 2e-28 UniRef50_UPI00015B56A3 Cluster: PREDICTED: similar to aldo-keto ... 122 2e-26 UniRef50_A5KSS3 Cluster: Aldehyde reductase; n=1; candidate divi... 122 2e-26 UniRef50_Q17DN1 Cluster: Aldo-keto reductase; n=1; Aedes aegypti... 121 2e-26 UniRef50_P14550 Cluster: Alcohol dehydrogenase [NADP+]; n=44; Bi... 121 2e-26 UniRef50_UPI0000588153 Cluster: PREDICTED: hypothetical protein;... 120 4e-26 UniRef50_Q17DN0 Cluster: Aldo-keto reductase; n=5; Culicidae|Rep... 120 7e-26 UniRef50_A2QBD7 Cluster: Catalytic activity: an alcohol + NADP(+... 118 2e-25 UniRef50_UPI000065D0BD Cluster: Homolog of Homo sapiens "AKR1B1 ... 117 3e-25 UniRef50_Q96JD6-2 Cluster: Isoform 2 of Q96JD6 ; n=4; Catarrhini... 117 3e-25 UniRef50_Q7QVQ9 Cluster: GLP_302_44328_45269; n=1; Giardia lambl... 117 3e-25 UniRef50_Q96JD6 Cluster: Aldo-keto reductase family 1 member C-l... 117 3e-25 UniRef50_Q0VGY1 Cluster: 3-alpha-hydroxysteroid dehydrogenase; n... 116 8e-25 UniRef50_Q7QK25 Cluster: ENSANGP00000019775; n=2; Anopheles gamb... 114 2e-24 UniRef50_Q5BKE9 Cluster: LOC594893 protein; n=5; Xenopus tropica... 114 3e-24 UniRef50_Q96UH3 Cluster: Aldehyde reductase; n=13; Pezizomycotin... 114 3e-24 UniRef50_Q7JVH6 Cluster: LD24696p; n=2; Sophophora|Rep: LD24696p... 113 8e-24 UniRef50_Q2S340 Cluster: Aldehyde reductase; n=10; Bacteria|Rep:... 112 1e-23 UniRef50_A7SIT3 Cluster: Predicted protein; n=1; Nematostella ve... 112 1e-23 UniRef50_Q55FL3 Cluster: Aldo-keto reductase; n=2; Dictyostelium... 111 2e-23 UniRef50_Q7ZWA4 Cluster: Zgc:56622; n=6; cellular organisms|Rep:... 110 4e-23 UniRef50_Q8K023 Cluster: Aldo-keto reductase family 1 member C18... 110 4e-23 UniRef50_Q54B70 Cluster: Aldehyde reductase; n=2; Dictyostelium ... 110 5e-23 UniRef50_UPI0000E4A7CE Cluster: PREDICTED: similar to LOC553452 ... 109 7e-23 UniRef50_Q2V420 Cluster: Uncharacterized protein At2g37770.1; n=... 109 1e-22 UniRef50_Q0PGJ6 Cluster: Aldo-keto reductase; n=32; Magnoliophyt... 109 1e-22 UniRef50_UPI0000E45E29 Cluster: PREDICTED: similar to aldose red... 108 2e-22 UniRef50_A2R6Z3 Cluster: Catalytic activity: an alcohol + NADP(+... 107 3e-22 UniRef50_Q8VC28 Cluster: Aldo-keto reductase family 1 member C13... 107 3e-22 UniRef50_Q22352 Cluster: Putative uncharacterized protein T08H10... 105 2e-21 UniRef50_UPI0000499B0E Cluster: oxidoreductase, aldo/keto reduct... 105 2e-21 UniRef50_A4RQH8 Cluster: Predicted protein; n=2; Ostreococcus|Re... 105 2e-21 UniRef50_P51857 Cluster: 3-oxo-5-beta-steroid 4-dehydrogenase (E... 105 2e-21 UniRef50_UPI0000498F1F Cluster: oxidoreductase, aldo/keto reduct... 104 3e-21 UniRef50_A3U9Y0 Cluster: Aldehyde reductase; n=5; Bacteroidetes|... 103 6e-21 UniRef50_P27800 Cluster: Aldehyde reductase 1; n=18; root|Rep: A... 103 8e-21 UniRef50_Q10494 Cluster: Probable oxidoreductase C26F1.07; n=2; ... 102 1e-20 UniRef50_A2EYY6 Cluster: Oxidoreductase, aldo/keto reductase fam... 102 1e-20 UniRef50_UPI00015B4B22 Cluster: PREDICTED: similar to GA15457-PA... 101 2e-20 UniRef50_Q7PLK6 Cluster: CG40064-PA; n=1; Drosophila melanogaste... 101 2e-20 UniRef50_A2EHN6 Cluster: Oxidoreductase, aldo/keto reductase fam... 101 2e-20 UniRef50_Q01J82 Cluster: OSIGBa0152K17.5 protein; n=28; Magnolio... 101 3e-20 UniRef50_Q9U2J5 Cluster: Putative uncharacterized protein; n=2; ... 100 4e-20 UniRef50_Q16K66 Cluster: Aldo-keto reductase; n=2; Aedes aegypti... 100 6e-20 UniRef50_Q7ZA52 Cluster: Aldose reductase; n=6; Pezizomycotina|R... 99 7e-20 UniRef50_UPI0000D9A956 Cluster: PREDICTED: similar to aldo-keto ... 99 1e-19 UniRef50_Q6TY50 Cluster: Reductase 2; n=10; Magnoliophyta|Rep: R... 99 1e-19 UniRef50_A2QL02 Cluster: Putative frameshift; n=1; Aspergillus n... 99 1e-19 UniRef50_Q7XY49 Cluster: Mannose 6-phosphate reductase; n=1; Gri... 98 3e-19 UniRef50_Q0IBY6 Cluster: Alcohol dehydrogenase; n=2; Chroococcal... 97 4e-19 UniRef50_Q1YPE5 Cluster: Aldehyde reductase; n=7; Bacteria|Rep: ... 97 5e-19 UniRef50_UPI00015B4912 Cluster: PREDICTED: similar to aldo-keto ... 96 9e-19 UniRef50_A5AD50 Cluster: Putative uncharacterized protein; n=3; ... 96 9e-19 UniRef50_A3C1Z7 Cluster: Putative uncharacterized protein; n=2; ... 96 9e-19 UniRef50_P38715 Cluster: NADPH-dependent aldose reductase GRE3; ... 96 9e-19 UniRef50_Q8SSK6 Cluster: ALDOSE REDUCTASE; n=1; Encephalitozoon ... 96 1e-18 UniRef50_A2QVE5 Cluster: Similarity: shows similarity to several... 95 2e-18 UniRef50_P26690 Cluster: NAD(P)H-dependent 6'-deoxychalcone synt... 95 2e-18 UniRef50_Q68ST9 Cluster: Reductase AKOR2; n=2; Pleurotus djamor|... 95 2e-18 UniRef50_Q9Y020 Cluster: 3-dehydroecdysone 3beta-reductase precu... 93 9e-18 UniRef50_Q2UGR1 Cluster: Aldo/keto reductase family proteins; n=... 93 9e-18 UniRef50_Q9VHX4 Cluster: CG2767-PA; n=4; Endopterygota|Rep: CG27... 93 1e-17 UniRef50_A2FPE2 Cluster: Oxidoreductase, aldo/keto reductase fam... 93 1e-17 UniRef50_UPI0000519CC2 Cluster: PREDICTED: similar to CG2767-PA;... 92 1e-17 UniRef50_A7PNI3 Cluster: Chromosome chr1 scaffold_22, whole geno... 92 1e-17 UniRef50_Q0CLQ2 Cluster: Putative uncharacterized protein; n=1; ... 92 1e-17 UniRef50_Q4FY75 Cluster: Aldo-keto reductase-like protein; n=5; ... 91 3e-17 UniRef50_P82125 Cluster: 1,5-anhydro-D-fructose reductase; n=1; ... 91 3e-17 UniRef50_Q5T2L2 Cluster: Aldo-keto reductase family 1 member C-l... 91 3e-17 UniRef50_Q6NII7 Cluster: Putative oxidoreductase; n=2; Corynebac... 90 6e-17 UniRef50_Q05KR9 Cluster: Benzil reductase; n=5; Bacillales|Rep: ... 90 6e-17 UniRef50_Q4PDR0 Cluster: Putative uncharacterized protein; n=1; ... 90 6e-17 UniRef50_Q7G764 Cluster: Probable NAD(P)H-dependent oxidoreducta... 90 6e-17 UniRef50_Q5KI95 Cluster: Aldo-keto reductase, putative; n=14; Di... 90 8e-17 UniRef50_Q7G765 Cluster: Probable NAD(P)H-dependent oxidoreducta... 89 1e-16 UniRef50_P23901 Cluster: Aldose reductase; n=9; Poaceae|Rep: Ald... 89 1e-16 UniRef50_Q41399 Cluster: Chalcone reductase; n=4; eudicotyledons... 89 1e-16 UniRef50_Q6RZX1 Cluster: Gld1; n=22; Pezizomycotina|Rep: Gld1 - ... 89 1e-16 UniRef50_Q4PAT5 Cluster: Putative uncharacterized protein; n=1; ... 89 1e-16 UniRef50_Q1IN88 Cluster: Aldehyde reductase; n=5; Bacteria|Rep: ... 89 2e-16 UniRef50_A1D4E3 Cluster: D-xylose reductase (Xyl1), putative; n=... 89 2e-16 UniRef50_Q1U9L6 Cluster: 2,5-didehydrogluconate reductase; n=3; ... 88 2e-16 UniRef50_Q17G72 Cluster: Aldo-keto reductase; n=9; Endopterygota... 88 2e-16 UniRef50_A5E082 Cluster: GCY protein; n=4; Saccharomycetales|Rep... 88 2e-16 UniRef50_Q6CFG7 Cluster: Yarrowia lipolytica chromosome B of str... 87 4e-16 UniRef50_Q9FJK0 Cluster: Aldose reductase-like protein; n=3; cor... 87 6e-16 UniRef50_UPI000023D0F1 Cluster: hypothetical protein FG03517.1; ... 87 7e-16 UniRef50_P38115 Cluster: D-arabinose dehydrogenase [NAD(P)+] hea... 87 7e-16 UniRef50_UPI00015B5BD7 Cluster: PREDICTED: similar to aldo-keto ... 86 1e-15 UniRef50_A6W8E7 Cluster: 2,5-didehydrogluconate reductase; n=3; ... 86 1e-15 UniRef50_Q8J0K1 Cluster: 4-dihydromethyltrisporate dehydrogenase... 86 1e-15 UniRef50_A6RKL9 Cluster: Putative uncharacterized protein; n=3; ... 86 1e-15 UniRef50_A6ESC0 Cluster: ARA1; n=1; unidentified eubacterium SCB... 85 2e-15 UniRef50_Q3E9M9 Cluster: Uncharacterized protein At5g01670.2; n=... 85 2e-15 UniRef50_P28475 Cluster: NADP-dependent D-sorbitol-6-phosphate d... 85 2e-15 UniRef50_Q03PG5 Cluster: Aldo/keto reductase of diketogulonate r... 84 4e-15 UniRef50_Q41E86 Cluster: 2,5-didehydrogluconate reductase; n=2; ... 84 5e-15 UniRef50_Q8WRT0 Cluster: 3-dehydrecdysone 3b-reductase; n=1; Tri... 83 7e-15 UniRef50_Q24C22 Cluster: Oxidoreductase, aldo/keto reductase fam... 83 7e-15 UniRef50_Q838E0 Cluster: Oxidoreductase, aldo/keto reductase fam... 83 9e-15 UniRef50_Q8F1G4 Cluster: Aldehyde reductase; n=8; Bacteria|Rep: ... 82 2e-14 UniRef50_Q7PM68 Cluster: ENSANGP00000014386; n=1; Anopheles gamb... 82 2e-14 UniRef50_A6SI80 Cluster: Putative uncharacterized protein; n=1; ... 82 2e-14 UniRef50_P14065 Cluster: Protein GCY; n=13; Saccharomycetales|Re... 82 2e-14 UniRef50_Q4JX70 Cluster: Putative oxidoreductase; n=1; Corynebac... 82 2e-14 UniRef50_Q03TW0 Cluster: Aldo/keto reductase of diketogulonate r... 81 3e-14 UniRef50_Q01HB5 Cluster: OSIGBa0136O08-OSIGBa0153H12.9 protein; ... 81 3e-14 UniRef50_Q03XK0 Cluster: Aldo/keto reductase of diketogulonate r... 81 4e-14 UniRef50_P22045 Cluster: Probable reductase; n=101; cellular org... 81 4e-14 UniRef50_Q7R2T6 Cluster: GLP_291_56367_57278; n=1; Giardia lambl... 81 5e-14 UniRef50_Q9HGY0 Cluster: Glycerol dehydrogenase; n=8; Saccharomy... 81 5e-14 UniRef50_Q6C2L0 Cluster: Yarrowia lipolytica chromosome F of str... 81 5e-14 UniRef50_A2QB88 Cluster: Contig An01c0460, complete genome. prec... 81 5e-14 UniRef50_P06632 Cluster: 2,5-diketo-D-gluconic acid reductase A;... 81 5e-14 UniRef50_Q23320 Cluster: Putative uncharacterized protein; n=4; ... 80 6e-14 UniRef50_UPI00015B40FA Cluster: PREDICTED: similar to CG2767-PA;... 80 9e-14 UniRef50_UPI00005A2CCB Cluster: PREDICTED: similar to Aldose red... 80 9e-14 UniRef50_Q7N0E4 Cluster: 2,5-diketo-D-gluconic acid reductase A;... 80 9e-14 UniRef50_Q1VRG6 Cluster: YvgN; n=1; Psychroflexus torquis ATCC 7... 80 9e-14 UniRef50_Q03X85 Cluster: Aldo/keto reductase of diketogulonate r... 80 9e-14 UniRef50_A7BA05 Cluster: Putative uncharacterized protein; n=1; ... 80 9e-14 UniRef50_Q4P4P1 Cluster: Putative uncharacterized protein; n=1; ... 79 1e-13 UniRef50_Q4PHK0 Cluster: Putative uncharacterized protein; n=1; ... 79 1e-13 UniRef50_Q9ZBW7 Cluster: Putative oxidoreductase; n=2; Actinomyc... 79 2e-13 UniRef50_Q5HR31 Cluster: Oxidoreductase, aldo/keto reductase fam... 79 2e-13 UniRef50_A6WDZ5 Cluster: Aldo/keto reductase; n=5; Bacteria|Rep:... 79 2e-13 UniRef50_Q6WGK4 Cluster: Aldose reductase; n=1; Pristionchus pac... 79 2e-13 UniRef50_Q88SL1 Cluster: Oxidoreductase; n=51; Lactobacillales|R... 78 3e-13 UniRef50_Q83N50 Cluster: 2,5-diketo-D-gluconic acid reductase; n... 78 3e-13 UniRef50_Q5TNP1 Cluster: ENSANGP00000029046; n=2; Culicidae|Rep:... 78 3e-13 UniRef50_A7RRF6 Cluster: Predicted protein; n=2; Nematostella ve... 78 3e-13 UniRef50_A3LTU8 Cluster: D-arabinose dehydrogenase; n=5; Sacchar... 78 3e-13 UniRef50_UPI00006CD296 Cluster: oxidoreductase, aldo/keto reduct... 78 3e-13 UniRef50_Q5FK98 Cluster: Oxidoreductase; n=8; Lactobacillales|Re... 77 5e-13 UniRef50_Q568D7 Cluster: Zgc:110366; n=7; Euteleostomi|Rep: Zgc:... 77 6e-13 UniRef50_UPI0000DB6EE9 Cluster: PREDICTED: similar to C35D10.6; ... 76 1e-12 UniRef50_Q929C8 Cluster: Lin2349 protein; n=12; Listeria|Rep: Li... 76 1e-12 UniRef50_Q9A2X8 Cluster: Oxidoreductase, aldo/keto reductase fam... 76 1e-12 UniRef50_A7CWF9 Cluster: Aldehyde reductase; n=2; Bacteria|Rep: ... 76 1e-12 UniRef50_Q0DHN0 Cluster: Os05g0456200 protein; n=2; Oryza sativa... 76 1e-12 UniRef50_Q968S3 Cluster: Aldoketoreductase-like protein; n=1; Or... 76 1e-12 UniRef50_Q5FT75 Cluster: Putative 2,5-diketo-D-gluconic acid red... 75 2e-12 UniRef50_A6LZ55 Cluster: 2,5-didehydrogluconate reductase; n=1; ... 75 2e-12 UniRef50_A0JX62 Cluster: 2,5-didehydrogluconate reductase; n=9; ... 75 2e-12 UniRef50_Q013C5 Cluster: Glycerol dehydrogenase, putative; n=2; ... 75 2e-12 UniRef50_Q1RFP0 Cluster: 2,5-diketo-D-gluconic acid reductase A;... 75 2e-12 UniRef50_A7CUW0 Cluster: 2,5-didehydrogluconate reductase; n=6; ... 75 3e-12 UniRef50_P91021 Cluster: Putative uncharacterized protein; n=1; ... 75 3e-12 UniRef50_A5ZYE6 Cluster: Putative uncharacterized protein; n=1; ... 74 4e-12 UniRef50_Q14LU6 Cluster: Putative aldo/keto reductase oxidoreduc... 74 6e-12 UniRef50_Q54NR2 Cluster: Aldo-keto reductase; n=3; Dictyostelium... 74 6e-12 UniRef50_Q4Q5N9 Cluster: Prostaglandin f synthase, putative; n=7... 73 7e-12 UniRef50_Q5V6N9 Cluster: Alcohol dehydrogenase; n=2; Halobacteri... 73 7e-12 UniRef50_Q1DLF1 Cluster: Putative uncharacterized protein; n=1; ... 73 1e-11 UniRef50_P70883 Cluster: AkrI; n=1; Butyrivibrio fibrisolvens|Re... 72 2e-11 UniRef50_O13848 Cluster: NADH/NADPH dependent indole-3-acetaldeh... 72 2e-11 UniRef50_Q5BLA6 Cluster: Zgc:110782; n=2; Danio rerio|Rep: Zgc:1... 72 2e-11 UniRef50_Q89JN4 Cluster: Oxidoreductase; n=8; Rhizobiales|Rep: O... 72 2e-11 UniRef50_A6NPD6 Cluster: Putative uncharacterized protein; n=3; ... 72 2e-11 UniRef50_Q8ZI40 Cluster: 2,5-diketo-D-gluconic acid reductase A;... 72 2e-11 UniRef50_Q9X0A2 Cluster: Oxidoreductase, aldo/keto reductase fam... 71 3e-11 UniRef50_Q7VG53 Cluster: Aldo-keto reductase; n=28; Bacteria|Rep... 71 3e-11 UniRef50_Q6U5V3 Cluster: Putative uncharacterized protein; n=1; ... 71 3e-11 UniRef50_A3VRL4 Cluster: Putative uncharacterized protein; n=1; ... 71 3e-11 UniRef50_A6RMS0 Cluster: Putative uncharacterized protein; n=1; ... 71 3e-11 UniRef50_Q7NB44 Cluster: ARA1; n=3; Firmicutes|Rep: ARA1 - Mycop... 71 4e-11 UniRef50_Q6F7K7 Cluster: 2,5-diketo-D-gluconate reductase; n=20;... 71 4e-11 UniRef50_Q11BF8 Cluster: Aldo/keto reductase; n=12; Bacteria|Rep... 71 4e-11 UniRef50_Q235V6 Cluster: Oxidoreductase, aldo/keto reductase fam... 71 4e-11 UniRef50_Q18483 Cluster: Putative uncharacterized protein; n=2; ... 71 4e-11 UniRef50_Q17568 Cluster: Putative uncharacterized protein; n=1; ... 71 4e-11 UniRef50_A6QXT4 Cluster: Predicted protein; n=1; Ajellomyces cap... 71 4e-11 UniRef50_Q4WF80 Cluster: Glycerol dehydrogenase (GCY1), putative... 71 5e-11 UniRef50_Q2U219 Cluster: Aldo/keto reductase family proteins; n=... 71 5e-11 UniRef50_Q5FKI1 Cluster: Reductase-dehydrogenase; n=1; Lactobaci... 70 7e-11 UniRef50_Q4V008 Cluster: Oxidoreductase; n=4; Proteobacteria|Rep... 70 7e-11 UniRef50_A0JRJ6 Cluster: Aldo/keto reductase; n=2; Micrococcinea... 70 7e-11 UniRef50_A7TLC4 Cluster: Putative uncharacterized protein; n=1; ... 70 7e-11 UniRef50_Q03U37 Cluster: Aldo/keto reductase of diketogulonate r... 70 9e-11 UniRef50_A5VK30 Cluster: 2,5-didehydrogluconate reductase; n=2; ... 70 9e-11 UniRef50_A5BF24 Cluster: Putative uncharacterized protein; n=1; ... 70 9e-11 UniRef50_Q2H1Q3 Cluster: Putative uncharacterized protein; n=1; ... 70 9e-11 UniRef50_P47137 Cluster: Probable oxidoreductase YJR096W; n=8; S... 70 9e-11 UniRef50_A7P424 Cluster: Chromosome chr1 scaffold_5, whole genom... 69 1e-10 UniRef50_Q7M4N1 Cluster: Dihydrodiol dehydrogenase DD2; n=2; Hom... 69 1e-10 UniRef50_O14088 Cluster: Xylose and arabinose reductase; n=1; Sc... 69 1e-10 UniRef50_Q890A0 Cluster: Oxidoreductase; n=6; Lactobacillales|Re... 69 2e-10 UniRef50_A3UJS6 Cluster: Oxidoreductase; n=3; Alphaproteobacteri... 69 2e-10 UniRef50_Q5B034 Cluster: Putative uncharacterized protein; n=1; ... 69 2e-10 UniRef50_A2UAH0 Cluster: Aldo/keto reductase; n=1; Bacillus coag... 69 2e-10 UniRef50_Q5XJM7 Cluster: Zgc:101765; n=5; Eumetazoa|Rep: Zgc:101... 68 3e-10 UniRef50_A7ALH6 Cluster: Putative uncharacterized protein; n=1; ... 68 4e-10 UniRef50_A1UEC5 Cluster: 2,5-didehydrogluconate reductase; n=20;... 68 4e-10 UniRef50_Q572D2 Cluster: Aldo-keto reductase, putative; n=1; Phy... 67 5e-10 UniRef50_Q4WUF7 Cluster: Aldo-keto reductase, putative; n=3; Pez... 67 5e-10 UniRef50_Q07551 Cluster: NADPH-dependent alpha-keto amide reduct... 67 5e-10 UniRef50_Q8G7K9 Cluster: Dehydrogenase or reductase protein; n=4... 67 6e-10 UniRef50_A2RMU6 Cluster: Oxidoreductase, aldo/keto reductase fam... 67 6e-10 UniRef50_A7D761 Cluster: Aldo/keto reductase; n=2; Halobacteriac... 67 6e-10 UniRef50_Q88TV9 Cluster: Oxidoreductase; n=4; Lactobacillus|Rep:... 66 9e-10 UniRef50_Q15NA5 Cluster: Aldo/keto reductase; n=2; Gammaproteoba... 66 9e-10 UniRef50_A4YQ04 Cluster: 2,5-diketo-D-gluconate reductase B; n=1... 66 9e-10 UniRef50_A3WP89 Cluster: Aldo/keto reductase; n=1; Idiomarina ba... 66 9e-10 UniRef50_Q21274 Cluster: Putative uncharacterized protein; n=1; ... 66 9e-10 UniRef50_Q09632 Cluster: Probable oxidoreductase ZK1290.5; n=2; ... 66 9e-10 UniRef50_Q0SFM4 Cluster: Probable 2,5-didehydrogluconate reducta... 66 1e-09 UniRef50_A1CAM7 Cluster: Aldo-keto reductase, putative; n=9; Dik... 66 1e-09 UniRef50_Q8ET73 Cluster: 2,5-diketo-D-gluconate reductase; n=12;... 66 1e-09 UniRef50_Q9ZUJ6 Cluster: T2K10.1 protein; n=16; core eudicotyled... 66 1e-09 UniRef50_Q00XM4 Cluster: Aldo/keto reductase family proteins; n=... 66 1e-09 UniRef50_A0JRJ3 Cluster: 2,5-didehydrogluconate reductase; n=3; ... 65 2e-09 UniRef50_Q4WP69 Cluster: Aldehyde reductase, putative; n=1; Aspe... 65 2e-09 UniRef50_UPI00006CCCD7 Cluster: oxidoreductase, aldo/keto reduct... 65 3e-09 UniRef50_Q927E1 Cluster: Lin2848 protein; n=13; Listeria|Rep: Li... 65 3e-09 UniRef50_Q5NLW3 Cluster: Putative oxidoreductase; n=1; Zymomonas... 65 3e-09 UniRef50_Q5FLI5 Cluster: Aldehyde reductase; n=2; Bacteria|Rep: ... 65 3e-09 UniRef50_Q28P63 Cluster: Aldo/keto reductase; n=4; Rhodobacterac... 65 3e-09 UniRef50_A5DRJ6 Cluster: Putative uncharacterized protein; n=4; ... 65 3e-09 UniRef50_A4R217 Cluster: Putative uncharacterized protein; n=1; ... 65 3e-09 UniRef50_Q8ZH36 Cluster: 2,5-diketo-D-gluconic acid reductase B;... 65 3e-09 UniRef50_Q8EUH6 Cluster: Oxidoreductase; n=1; Mycoplasma penetra... 64 3e-09 UniRef50_A3JU52 Cluster: 2,5-diketo-D-gluconic acid reductase A;... 64 3e-09 UniRef50_Q7WSY4 Cluster: Putative aldo-keto reductase; n=1; Prop... 64 5e-09 UniRef50_Q043M4 Cluster: Aldo/keto reductase of diketogulonate r... 64 5e-09 UniRef50_P15339 Cluster: 2,5-diketo-D-gluconic acid reductase B;... 64 5e-09 UniRef50_Q5UX52 Cluster: Oxidoreductase aldo/keto reductase fami... 64 6e-09 UniRef50_A3VHZ9 Cluster: Oxidoreductase; n=1; Rhodobacterales ba... 63 8e-09 UniRef50_Q5V663 Cluster: Aldehyde reductase; n=6; Halobacteriace... 63 8e-09 UniRef50_UPI00006CA3CB Cluster: oxidoreductase, aldo/keto reduct... 63 1e-08 UniRef50_A5PDA8 Cluster: Putative oxidoreductase protein; n=1; E... 63 1e-08 UniRef50_Q9C1X5 Cluster: Xylose and arabinose reductase; n=1; Sc... 62 1e-08 UniRef50_Q75E75 Cluster: ABL209Cp; n=1; Eremothecium gossypii|Re... 62 1e-08 UniRef50_Q5K8C5 Cluster: Aldo-keto reductase, putative; n=1; Fil... 62 1e-08 UniRef50_Q5B5R6 Cluster: Putative uncharacterized protein; n=1; ... 62 1e-08 UniRef50_Q927P9 Cluster: Lin2739 protein; n=12; Bacteria|Rep: Li... 62 2e-08 UniRef50_Q64UK5 Cluster: Aldo/keto reductase family oxidoreducta... 62 2e-08 UniRef50_UPI0001556575 Cluster: PREDICTED: similar to Aldo-keto ... 62 2e-08 UniRef50_Q7VHE1 Cluster: Putative uncharacterized protein; n=1; ... 62 2e-08 UniRef50_Q02198 Cluster: Morphine 6-dehydrogenase; n=5; Bacteria... 62 2e-08 UniRef50_Q6CEJ0 Cluster: Yarrowia lipolytica chromosome B of str... 61 3e-08 UniRef50_Q5KKZ8 Cluster: Aldo-keto reductase, putative; n=2; Fil... 61 3e-08 UniRef50_Q1M4Z6 Cluster: Putative aldo-keto reductase/oxidase; n... 61 4e-08 UniRef50_Q4DJ59 Cluster: Aldo/keto reductase, putative; n=2; Try... 61 4e-08 UniRef50_Q9P734 Cluster: Related to 2, 5-diketo-D-gluconic acid ... 61 4e-08 UniRef50_Q1Q8W8 Cluster: Aldo/keto reductase; n=1; Psychrobacter... 60 6e-08 UniRef50_A0L1A2 Cluster: Aldo/keto reductase; n=8; Gammaproteoba... 60 6e-08 UniRef50_Q4PE96 Cluster: Putative uncharacterized protein; n=1; ... 60 6e-08 UniRef50_Q5KCN9 Cluster: Putative uncharacterized protein; n=1; ... 60 7e-08 UniRef50_Q5V398 Cluster: Oxidoreductase aldo/keto reductase fami... 60 7e-08 UniRef50_Q8Y463 Cluster: Lmo2592 protein; n=40; Bacteria|Rep: Lm... 60 1e-07 UniRef50_Q11DV1 Cluster: Aldo/keto reductase; n=10; Alphaproteob... 60 1e-07 UniRef50_P91997 Cluster: Putative uncharacterized protein; n=4; ... 60 1e-07 UniRef50_A7PNT1 Cluster: Chromosome chr8 scaffold_23, whole geno... 59 1e-07 UniRef50_A7BES9 Cluster: Putative uncharacterized protein; n=1; ... 59 2e-07 UniRef50_A0AWM8 Cluster: Aldo/keto reductase; n=4; Actinomycetal... 58 2e-07 UniRef50_A5BYJ4 Cluster: Putative uncharacterized protein; n=1; ... 58 2e-07 UniRef50_Q5FK99 Cluster: Oxidoreductase aldo-keto reductase fami... 58 3e-07 UniRef50_A4FEB9 Cluster: 2,5-diketo-D-gluconic acid reductase; n... 58 3e-07 UniRef50_Q6L139 Cluster: 2,5-diketo-D-gluconic acid reductase; n... 58 3e-07 UniRef50_Q0UQ60 Cluster: Putative uncharacterized protein; n=1; ... 58 4e-07 UniRef50_Q5KD52 Cluster: Oxidoreductase, putative; n=1; Filobasi... 57 5e-07 UniRef50_Q9X265 Cluster: Oxidoreductase, aldo/keto reductase fam... 57 7e-07 UniRef50_Q76L37 Cluster: Conjugated polyketone reductase C1; n=3... 56 9e-07 UniRef50_Q8EVS8 Cluster: Oxidoreductase; n=1; Mycoplasma penetra... 56 1e-06 UniRef50_A6VNW9 Cluster: Aldo/keto reductase precursor; n=1; Act... 56 1e-06 UniRef50_Q5BC40 Cluster: Putative uncharacterized protein; n=1; ... 56 1e-06 UniRef50_UPI000023DF27 Cluster: hypothetical protein FG07276.1; ... 55 3e-06 UniRef50_A7SGW6 Cluster: Predicted protein; n=1; Nematostella ve... 54 4e-06 UniRef50_A6RYK4 Cluster: Putative uncharacterized protein; n=1; ... 54 4e-06 UniRef50_Q8EVT8 Cluster: Oxidoreductase-aldo/keto reductase fami... 54 5e-06 UniRef50_A7RPK2 Cluster: Predicted protein; n=1; Nematostella ve... 54 6e-06 UniRef50_Q76L36 Cluster: Conjugated polyketone reductase C2; n=1... 54 6e-06 UniRef50_Q8DK16 Cluster: Tlr1054 protein; n=6; Cyanobacteria|Rep... 53 8e-06 UniRef50_Q3CZS2 Cluster: Oxidoreductase, aldo/keto reductase fam... 53 8e-06 UniRef50_Q11B35 Cluster: Aldo/keto reductase; n=1; Mesorhizobium... 53 8e-06 UniRef50_Q9P6D3 Cluster: Related to aldo-keto reductase YPR1; n=... 53 8e-06 UniRef50_Q5UYI9 Cluster: Oxidoreductase; n=1; Haloarcula marismo... 53 8e-06 UniRef50_A3T261 Cluster: Putative uncharacterized protein; n=1; ... 53 1e-05 UniRef50_A7RUA2 Cluster: Predicted protein; n=1; Nematostella ve... 53 1e-05 UniRef50_Q9USV2 Cluster: Xylose and arabinose reductase; n=2; Sc... 53 1e-05 UniRef50_A7D6Q0 Cluster: Aldo/keto reductase; n=1; Halorubrum la... 53 1e-05 UniRef50_UPI000023DA24 Cluster: hypothetical protein FG10036.1; ... 52 1e-05 UniRef50_A2WWZ1 Cluster: Putative uncharacterized protein; n=1; ... 52 2e-05 UniRef50_Q0CK00 Cluster: Predicted protein; n=1; Aspergillus ter... 52 2e-05 UniRef50_Q979I4 Cluster: Aldo / keto reductase; n=3; Archaea|Rep... 52 2e-05 UniRef50_A7D6I8 Cluster: Aldo/keto reductase; n=1; Halorubrum la... 52 2e-05 UniRef50_A1CLD1 Cluster: Gamma-cysteine synthetase regulatory su... 52 3e-05 UniRef50_Q5V1M9 Cluster: Oxidoreductase aldo/keto reductase fami... 52 3e-05 UniRef50_Q2CAL9 Cluster: 2,5-didehydrogluconate reductase; n=2; ... 51 3e-05 UniRef50_Q2H7A8 Cluster: Putative uncharacterized protein; n=1; ... 51 3e-05 UniRef50_Q5KKC5 Cluster: Putative uncharacterized protein; n=2; ... 51 5e-05 UniRef50_Q59Z55 Cluster: Potential aldo/keto reductase; n=6; Sac... 50 6e-05 UniRef50_Q4Q973 Cluster: Aldo/keto reductase, putative; n=3; Lei... 50 8e-05 UniRef50_Q18903 Cluster: Putative uncharacterized protein C56G3.... 50 8e-05 UniRef50_A2FJN9 Cluster: Putative uncharacterized protein; n=4; ... 50 8e-05 UniRef50_A1RB46 Cluster: 2,5-diketo-D-gluconate reductase; n=1; ... 50 1e-04 UniRef50_Q4WI64 Cluster: Aldehyde reductase, putative; n=22; Pez... 50 1e-04 UniRef50_Q9HM42 Cluster: Alcohol dehydrogenase related protein; ... 50 1e-04 UniRef50_Q97U17 Cluster: Oxidoreductase, aldo/keto reductase fam... 49 2e-04 UniRef50_A7D7K7 Cluster: Aldo/keto reductase; n=1; Halorubrum la... 48 2e-04 UniRef50_Q61U89 Cluster: Putative uncharacterized protein CBG054... 48 3e-04 UniRef50_A7EW94 Cluster: Putative uncharacterized protein; n=1; ... 48 3e-04 UniRef50_UPI0000611A01 Cluster: PREDICTED: similar to MGC80525 p... 48 4e-04 UniRef50_Q6CGE9 Cluster: Similar to sp|P47137 Saccharomyces cere... 48 4e-04 UniRef50_Q4JCC1 Cluster: 2,5-diketo-D-gluconic acid reductase A;... 48 4e-04 UniRef50_Q55FL2 Cluster: Putative uncharacterized protein; n=1; ... 47 6e-04 UniRef50_Q2BBN7 Cluster: YvgN; n=1; Bacillus sp. NRRL B-14911|Re... 47 7e-04 UniRef50_UPI0000D9C1BD Cluster: PREDICTED: similar to aldo-keto ... 46 0.001 UniRef50_Q14LA8 Cluster: Putative aldo/keto reductase oxidoreduc... 46 0.001 UniRef50_Q4P1G1 Cluster: Putative uncharacterized protein; n=1; ... 46 0.001 UniRef50_A3LWP0 Cluster: Aldo/keto reductase; n=7; Saccharomycet... 46 0.001 UniRef50_Q87SA8 Cluster: Oxidoreductase Tas, aldo/keto reductase... 46 0.002 UniRef50_UPI000155CAC7 Cluster: PREDICTED: hypothetical protein;... 45 0.002 UniRef50_A4IJ00 Cluster: LOC548351 protein; n=1; Xenopus tropica... 45 0.002 UniRef50_Q872E2 Cluster: Related to gamma-glutamylcysteine synth... 45 0.002 UniRef50_Q016B0 Cluster: COG0667: Predicted oxidoreductases; n=4... 45 0.003 UniRef50_Q97V56 Cluster: Dehydrogenase; n=8; Thermoprotei|Rep: D... 44 0.004 UniRef50_Q89RG2 Cluster: Aldo/keto reductase; n=11; Bacteria|Rep... 44 0.005 UniRef50_A3H9Y8 Cluster: Aldo/keto reductase; n=2; Caldivirga ma... 44 0.005 UniRef50_A0RYR0 Cluster: Oxidoreductase; n=2; cellular organisms... 44 0.005 UniRef50_Q7NK63 Cluster: Gll1617 protein; n=1; Gloeobacter viola... 44 0.007 UniRef50_Q64W37 Cluster: 2,5-diketo-D-gluconic acid reductase; n... 43 0.012 UniRef50_Q1PV10 Cluster: Putative uncharacterized protein; n=1; ... 43 0.012 UniRef50_Q2JHT1 Cluster: Aldo/keto reductase Tas; n=25; cellular... 42 0.016 UniRef50_Q59ZT1 Cluster: Putative uncharacterized protein; n=1; ... 42 0.016 UniRef50_Q16CS5 Cluster: 2,5-diketo-D-gluconic acid reductase B,... 42 0.021 UniRef50_Q6CWB9 Cluster: Similarities with sp|Q12458 Saccharomyc... 42 0.021 UniRef50_Q55ML8 Cluster: Putative uncharacterized protein; n=2; ... 42 0.021 UniRef50_O94246 Cluster: Glutamate-cysteine ligase regulatory su... 42 0.021 UniRef50_P49261 Cluster: Rho beta-crystallin; n=1; Lepidodactylu... 42 0.021 UniRef50_Q81RN9 Cluster: Oxidoreductase, aldo/keto reductase fam... 42 0.028 UniRef50_A6R5B4 Cluster: NAD(P)H-dependent D-xylose reductase; n... 42 0.028 UniRef50_Q966L2 Cluster: Putative uncharacterized protein; n=2; ... 41 0.037 UniRef50_Q09D95 Cluster: Ydhf chain A; n=1; Stigmatella aurantia... 40 0.064 UniRef50_Q9ZUX0 Cluster: Expressed protein; n=11; cellular organ... 40 0.064 UniRef50_Q9C2J8 Cluster: Related to D-xylose reductase II, III p... 40 0.064 UniRef50_A0RWV1 Cluster: Oxidoreductase; n=4; Thermoprotei|Rep: ... 40 0.064 UniRef50_Q9QWA5 Cluster: Aldose reductase; n=5; Euarchontoglires... 40 0.085 UniRef50_Q1IQ78 Cluster: Aldo/keto reductase; n=1; Acidobacteria... 40 0.085 UniRef50_A6BIJ0 Cluster: Putative uncharacterized protein; n=1; ... 40 0.085 UniRef50_Q9V2P1 Cluster: Myo-inositol degradation; n=5; Archaea|... 40 0.085 UniRef50_Q97UV9 Cluster: Oxidoreductase; n=1; Sulfolobus solfata... 40 0.085 UniRef50_Q60BI7 Cluster: Oxidoreductase, aldo/keto reductase fam... 40 0.11 UniRef50_A2G4I3 Cluster: Oxidoreductase, aldo/keto reductase fam... 40 0.11 UniRef50_Q2SL81 Cluster: Predicted oxidoreductase; n=10; Bacteri... 39 0.15 UniRef50_Q0RZJ9 Cluster: Possible transporter, MFS superfamily p... 39 0.15 UniRef50_P0A9T5 Cluster: Protein tas; n=88; Bacteria|Rep: Protei... 39 0.15 UniRef50_Q82NW9 Cluster: Putative oxidoreductase; n=3; Streptomy... 39 0.20 UniRef50_A6PR52 Cluster: Aldo/keto reductase; n=1; Victivallis v... 39 0.20 UniRef50_Q8EUX1 Cluster: Aldo/keto reductase family oxidoreducta... 38 0.26 UniRef50_Q5ZTU6 Cluster: D-xylose reductase III; n=5; Legionella... 38 0.26 UniRef50_A4QYG8 Cluster: Putative uncharacterized protein; n=1; ... 38 0.26 UniRef50_Q6L0T3 Cluster: Oxidoreductase; n=2; Thermoplasmatales|... 38 0.26 UniRef50_Q0GU15 Cluster: ORF28; n=3; Bacteria|Rep: ORF28 - Lacto... 38 0.34 UniRef50_A7PU13 Cluster: Chromosome chr7 scaffold_31, whole geno... 38 0.34 UniRef50_Q68A33 Cluster: Aldo-keto reductase 1a; n=1; Ciona inte... 38 0.34 UniRef50_UPI000023DAA9 Cluster: hypothetical protein FG00321.1; ... 38 0.45 UniRef50_Q21EY6 Cluster: Aldo/keto reductase; n=1; Saccharophagu... 38 0.45 UniRef50_Q0AL14 Cluster: Aldo/keto reductase; n=1; Maricaulis ma... 38 0.45 UniRef50_A7HEV1 Cluster: Aldo/keto reductase; n=13; Bacteria|Rep... 38 0.45 UniRef50_A0Y7Y8 Cluster: Aldo/keto reductase; n=1; marine gamma ... 38 0.45 UniRef50_UPI0000605361 Cluster: PREDICTED: hypothetical protein;... 37 0.60 UniRef50_UPI000038E317 Cluster: hypothetical protein Faci_030017... 37 0.60 UniRef50_A5GMY9 Cluster: Aldo/keto reductase family protein; n=2... 37 0.60 UniRef50_A3U5K6 Cluster: Oxidoreductase, aldo/keto reductase fam... 37 0.60 UniRef50_P93818 Cluster: F19P19.12 protein; n=4; Arabidopsis tha... 37 0.60 UniRef50_Q7S500 Cluster: Predicted protein; n=1; Neurospora cras... 37 0.60 UniRef50_Q5KQ01 Cluster: Pyridoxal reductase, putative; n=2; Fil... 37 0.60 UniRef50_A6QVW8 Cluster: Predicted protein; n=1; Ajellomyces cap... 37 0.60 UniRef50_UPI0000DAE567 Cluster: hypothetical protein Rgryl_01000... 37 0.79 UniRef50_Q5FHT2 Cluster: Aldehyde reductase; n=4; Lactobacillus|... 37 0.79 UniRef50_A0Q648 Cluster: Aldo/keto reductase family protein; n=1... 37 0.79 UniRef50_Q33BE9 Cluster: Aldo/keto reductase, putative; n=1; Ory... 37 0.79 UniRef50_Q8ID61 Cluster: Aldo-keto reductase, putative; n=6; Pla... 37 0.79 UniRef50_Q5FJ72 Cluster: Predicted oxidoreductase; n=1; Lactobac... 36 1.0 UniRef50_Q3I1P2 Cluster: Aldo-keto oxidoreductase; n=6; Bacteria... 36 1.0 UniRef50_A7RWF3 Cluster: Predicted protein; n=1; Nematostella ve... 36 1.0 UniRef50_Q8TZX3 Cluster: Glutamate synthase small subunit; n=2; ... 36 1.0 UniRef50_UPI0000DD8688 Cluster: PREDICTED: hypothetical protein;... 36 1.4 UniRef50_UPI000018356B Cluster: UPI000018356B related cluster; n... 36 1.4 UniRef50_Q7D001 Cluster: AGR_C_2023p; n=14; Proteobacteria|Rep: ... 36 1.4 UniRef50_A1ZSV4 Cluster: Oxidoreductase, aldo/keto reductase fam... 36 1.4 UniRef50_O13524 Cluster: B2-aldehyde-forming enzyme; n=1; Schizo... 36 1.4 UniRef50_Q9PCQ5 Cluster: Sugar-phosphate dehydrogenase; n=23; Ba... 36 1.8 UniRef50_Q1J2F9 Cluster: HRDC; n=1; Deinococcus geothermalis DSM... 36 1.8 UniRef50_Q4Q5X1 Cluster: Aldehyde reductase, putative; n=75; cel... 36 1.8 UniRef50_Q4P0M3 Cluster: Putative uncharacterized protein; n=1; ... 36 1.8 UniRef50_Q8ZU65 Cluster: Aldo-keto reductase, putative; n=4; The... 36 1.8 UniRef50_P76234 Cluster: Uncharacterized protein yeaE; n=39; Bac... 36 1.8 UniRef50_P40690 Cluster: Aldo-keto reductase; n=4; Piroplasmida|... 36 1.8 UniRef50_Q6GIV4 Cluster: Aldo/keto reductase family protein; n=1... 35 2.4 UniRef50_Q1FGT0 Cluster: Aldo/keto reductase; n=1; Clostridium p... 35 2.4 UniRef50_A7LSN6 Cluster: Putative uncharacterized protein; n=3; ... 35 2.4 UniRef50_A1WAL7 Cluster: Aldo/keto reductase; n=35; cellular org... 35 2.4 UniRef50_A0YC40 Cluster: Putative uncharacterized protein; n=1; ... 35 2.4 UniRef50_Q0D184 Cluster: Predicted protein; n=2; Trichocomaceae|... 35 2.4 UniRef50_UPI0000E21371 Cluster: PREDICTED: similar to Basic sali... 35 3.2 UniRef50_Q7WFM3 Cluster: Conserved hypothetical secreted protein... 35 3.2 UniRef50_A1B5W4 Cluster: Aldo/keto reductase; n=1; Paracoccus de... 35 3.2 UniRef50_A7T149 Cluster: Predicted protein; n=1; Nematostella ve... 35 3.2 UniRef50_P48507 Cluster: Glutamate--cysteine ligase regulatory s... 35 3.2 UniRef50_Q1IYI7 Cluster: Aldo/keto reductase; n=3; Deinococcus g... 34 4.2 UniRef50_Q0SFJ5 Cluster: Aryl-alcohol dehydrogenase; n=4; Actino... 34 4.2 UniRef50_A2TIR8 Cluster: Receptor for egg jelly protein 9; n=9; ... 34 4.2 UniRef50_Q94A68 Cluster: Uncharacterized oxidoreductase At1g0669... 34 4.2 UniRef50_Q67QT0 Cluster: Putative uncharacterized protein; n=1; ... 34 5.6 UniRef50_Q2SPS9 Cluster: Predicted oxidoreductase; n=5; Gammapro... 34 5.6 UniRef50_Q03BE0 Cluster: Aldo/keto reductase family enzyme; n=5;... 34 5.6 UniRef50_A7LW87 Cluster: Putative uncharacterized protein; n=1; ... 34 5.6 UniRef50_A2TW02 Cluster: Putative uncharacterized protein; n=1; ... 34 5.6 UniRef50_Q585N8 Cluster: Putative uncharacterized protein; n=1; ... 34 5.6 UniRef50_Q5KPU6 Cluster: Putative uncharacterized protein; n=2; ... 34 5.6 UniRef50_UPI0000D55EBD Cluster: PREDICTED: similar to CG16857-PA... 33 7.4 UniRef50_UPI0000447325 Cluster: PREDICTED: similar to aldo-keto ... 33 7.4 UniRef50_Q4TC86 Cluster: Chromosome undetermined SCAF7044, whole... 33 7.4 UniRef50_Q9X0R5 Cluster: Oxidoreductase, aldo/keto reductase fam... 33 7.4 UniRef50_Q837G5 Cluster: Oxidoreductase, aldo/keto reductase 2 f... 33 7.4 UniRef50_Q5FQE0 Cluster: Pseudouridine synthase; n=3; Acetobacte... 33 7.4 UniRef50_Q11KU9 Cluster: Twin-arginine translocation pathway sig... 33 7.4 UniRef50_A7M4Z2 Cluster: Putative uncharacterized protein; n=1; ... 33 7.4 UniRef50_A6VXU3 Cluster: Aldo/keto reductase; n=14; Proteobacter... 33 7.4 UniRef50_A2UBC7 Cluster: Aldo/keto reductase; n=3; cellular orga... 33 7.4 UniRef50_A0JZE6 Cluster: Aldo/keto reductase; n=1; Arthrobacter ... 33 7.4 UniRef50_Q6NKP1 Cluster: At5g53580; n=18; cellular organisms|Rep... 33 7.4 UniRef50_Q54CX8 Cluster: Putative uncharacterized protein; n=1; ... 33 7.4 UniRef50_Q6TRS1 Cluster: Oxidoreductase; n=1; Ustilago maydis|Re... 33 7.4 UniRef50_A5DLB5 Cluster: Putative uncharacterized protein; n=1; ... 33 7.4 UniRef50_Q88SS2 Cluster: Oxidoreductase; n=13; Firmicutes|Rep: O... 33 9.7 UniRef50_Q4HND9 Cluster: Oxidoreductase, aldo/keto reductase fam... 33 9.7 UniRef50_A7B2Y7 Cluster: Putative uncharacterized protein; n=1; ... 33 9.7 UniRef50_A6C2P2 Cluster: Oxidoreductase, aldo/keto reductase fam... 33 9.7 UniRef50_Q96JH4 Cluster: Protein KIAA1853; n=23; Tetrapoda|Rep: ... 33 9.7 UniRef50_A6R267 Cluster: Protein dopey; n=1; Ajellomyces capsula... 33 9.7 UniRef50_A3H7G3 Cluster: Aldo/keto reductase; n=2; Caldivirga ma... 33 9.7 UniRef50_A1RU35 Cluster: Putative uncharacterized protein; n=1; ... 33 9.7 UniRef50_P39635 Cluster: Protein rocB; n=6; Bacillus|Rep: Protei... 33 9.7 UniRef50_P82810 Cluster: Morphine 6-dehydrogenase; n=1; Oryctola... 33 9.7 >UniRef50_Q7PCV3 Cluster: ENSANGP00000031808; n=9; Endopterygota|Rep: ENSANGP00000031808 - Anopheles gambiae str. PEST Length = 316 Score = 150 bits (363), Expect = 5e-35 Identities = 67/92 (72%), Positives = 75/92 (81%) Frame = +3 Query: 180 PXFGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIKEGVVTREDL 359 P FGLGTW S PG+V QAVKDAID+GYRHIDCA+VY NE EVGE I +KI EGVV REDL Sbjct: 18 PMFGLGTWNSPPGQVAQAVKDAIDVGYRHIDCAHVYQNEHEVGEGIAAKIAEGVVKREDL 77 Query: 360 FITSKLWNTFHRPDLVRGALQETLEQSELSVL 455 F+TSKLWNTFHRPDLV GA + TL+ +L L Sbjct: 78 FVTSKLWNTFHRPDLVEGACKTTLQNLKLDYL 109 Score = 142 bits (344), Expect = 1e-32 Identities = 62/119 (52%), Positives = 78/119 (65%), Gaps = 1/119 (0%) Frame = +1 Query: 418 CRRPWNNLNFQYLDLYLIHWPQAYKEDGSLFPTDQSGK-IQFSDVDYVDTWKAMEPLVKE 594 C+ NL YLDLYLIHWP Y+E LFP GK FSD DYVDTW ME LV Sbjct: 97 CKTTLQNLKLDYLDLYLIHWPVGYQEGTELFPMGPDGKTFLFSDADYVDTWPEMEKLVDA 156 Query: 595 GLVKSIGVSNFNSKQLERLLXHAXVKPVVNXVECHPYLNXKRLKEFCXXRGVXIXXYSP 771 GLV++IGVSNFN+KQ++R+L A + P N +ECHPYL+ ++ FC +G+ + YSP Sbjct: 157 GLVRNIGVSNFNAKQVQRVLDVARIPPATNQIECHPYLHQSKITTFCAEKGIIVTAYSP 215 >UniRef50_UPI0000D56CE5 Cluster: PREDICTED: similar to CG6084-PA, isoform A; n=1; Tribolium castaneum|Rep: PREDICTED: similar to CG6084-PA, isoform A - Tribolium castaneum Length = 493 Score = 144 bits (348), Expect = 4e-33 Identities = 63/113 (55%), Positives = 82/113 (72%), Gaps = 1/113 (0%) Frame = +1 Query: 436 NLNFQYLDLYLIHWPQAYKEDGSLFPTD-QSGKIQFSDVDYVDTWKAMEPLVKEGLVKSI 612 NL YLD+YL+HWP A KE SL P D ++G SDVD+VDTWKAME + ++ L KSI Sbjct: 275 NLQLDYLDVYLMHWPHALKEGPSLHPIDPKTGLFIPSDVDFVDTWKAMEKMHEKDLTKSI 334 Query: 613 GVSNFNSKQLERLLXHAXVKPVVNXVECHPYLNXKRLKEFCXXRGVXIXXYSP 771 G+SNFNS Q++RLL A + PV+N +ECHPYLN +L++FC RG+ + YSP Sbjct: 335 GISNFNSNQIDRLLKSAKIAPVINQIECHPYLNQSKLRKFCSDRGITVTSYSP 387 Score = 95.9 bits (228), Expect = 1e-18 Identities = 47/111 (42%), Positives = 67/111 (60%) Frame = +1 Query: 439 LNFQYLDLYLIHWPQAYKEDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGV 618 L YLDLYLI P A K D + ++TW+AME L E L ++IG+ Sbjct: 102 LQVAYLDLYLIERPPACK-----------------DHNLIETWEAMEGLYSEKLTRAIGL 144 Query: 619 SNFNSKQLERLLXHAXVKPVVNXVECHPYLNXKRLKEFCXXRGVXIXXYSP 771 SNFNSKQ+ER+L + ++P VN ++CHPYLN +L+++C G+ + YSP Sbjct: 145 SNFNSKQIERILENCTIRPQVNQIQCHPYLNQAKLRKYCSNNGIAVISYSP 195 Score = 47.2 bits (107), Expect = 6e-04 Identities = 26/74 (35%), Positives = 46/74 (62%) Frame = +3 Query: 234 VKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIKEGVVTREDLFITSKLWNTFHRPDLVRG 413 V+ + YR +DC+ ++ NEK G A+ I+ G + R+DLF+ SK T + +LV+ Sbjct: 36 VQLVVSSNYRLMDCS-IFENEKRFGVALQQLIEGGKIRRKDLFLMSKFCCT-NTTNLVKA 93 Query: 414 ALQETLEQSELSVL 455 AL +TL++ +++ L Sbjct: 94 ALLDTLKKLQVAYL 107 >UniRef50_Q2LZ66 Cluster: GA19341-PA; n=2; Endopterygota|Rep: GA19341-PA - Drosophila pseudoobscura (Fruit fly) Length = 315 Score = 139 bits (337), Expect = 8e-32 Identities = 63/118 (53%), Positives = 76/118 (64%), Gaps = 1/118 (0%) Frame = +1 Query: 418 CRRPWNNLNFQYLDLYLIHWPQAYKEDGSLFPT-DQSGKIQFSDVDYVDTWKAMEPLVKE 594 C NL YLDLYL+HWP AYK +L+PT +GK F D+DY+DTWKAME LV Sbjct: 94 CETSLRNLGIDYLDLYLMHWPMAYKSGDNLYPTCPDTGKAVFEDIDYLDTWKAMEDLVDS 153 Query: 595 GLVKSIGVSNFNSKQLERLLXHAXVKPVVNXVECHPYLNXKRLKEFCXXRGVXIXXYS 768 GLV +IGVSNFN KQ+ RLL A +KPV+ +ECHPYL K L C + + YS Sbjct: 154 GLVNAIGVSNFNEKQINRLLCLAKLKPVMLQIECHPYLRQKSLITLCYDNAIGVTAYS 211 Score = 132 bits (320), Expect = 9e-30 Identities = 59/92 (64%), Positives = 71/92 (77%) Frame = +3 Query: 180 PXFGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIKEGVVTREDL 359 P GLGTW+S P V QAVKDAIDIGYRH DCA++YGNE VG AI KI+EG+VTR++L Sbjct: 15 PMVGLGTWRSPPEVVAQAVKDAIDIGYRHFDCAHIYGNELHVGVAIREKIQEGLVTRDEL 74 Query: 360 FITSKLWNTFHRPDLVRGALQETLEQSELSVL 455 FITSKLWNTFH+P+LVR A + +L + L Sbjct: 75 FITSKLWNTFHKPELVRAACETSLRNLGIDYL 106 >UniRef50_P45376 Cluster: Aldose reductase; n=21; Bilateria|Rep: Aldose reductase - Mus musculus (Mouse) Length = 316 Score = 138 bits (333), Expect = 2e-31 Identities = 62/115 (53%), Positives = 78/115 (67%), Gaps = 2/115 (1%) Frame = +1 Query: 433 NNLNFQYLDLYLIHWPQAYKEDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSI 612 ++L YLDLYLIHWP +K FP D SG + SD D+VDTW AME LV EGLVK+I Sbjct: 98 SDLQLDYLDLYLIHWPTGFKPGPDYFPLDASGNVIPSDTDFVDTWTAMEQLVDEGLVKTI 157 Query: 613 GVSNFNSKQLERLLXHAXV--KPVVNXVECHPYLNXKRLKEFCXXRGVXIXXYSP 771 GVSNFN Q+ER+L + KP VN +ECHPYL ++L E+C +G+ + YSP Sbjct: 158 GVSNFNPLQIERILNKPGLKYKPAVNQIECHPYLTQEKLIEYCHSKGIVVTAYSP 212 Score = 130 bits (315), Expect = 3e-29 Identities = 60/92 (65%), Positives = 70/92 (76%) Frame = +3 Query: 180 PXFGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIKEGVVTREDL 359 P GLGTWKS PG+VT+AVK AID+GYRHIDCA VY NEKEVG A+ K+KE VV R+DL Sbjct: 14 PTLGLGTWKSPPGQVTEAVKVAIDLGYRHIDCAQVYQNEKEVGVALQEKLKEQVVKRQDL 73 Query: 360 FITSKLWNTFHRPDLVRGALQETLEQSELSVL 455 FI SKLW TFH +V+GA Q+TL +L L Sbjct: 74 FIVSKLWCTFHDKSMVKGAFQKTLSDLQLDYL 105 >UniRef50_UPI00015B56A2 Cluster: PREDICTED: similar to GA10458-PA; n=2; Nasonia vitripennis|Rep: PREDICTED: similar to GA10458-PA - Nasonia vitripennis Length = 569 Score = 135 bits (326), Expect = 2e-30 Identities = 59/118 (50%), Positives = 80/118 (67%) Frame = +1 Query: 418 CRRPWNNLNFQYLDLYLIHWPQAYKEDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEG 597 C++ NL F Y+DL+L+HWP A+K +L P D +GKI+FSD DY++TWK ME ++G Sbjct: 94 CKKSLENLGFDYIDLFLVHWPFAFKSGDALTPRDAAGKIEFSDTDYLETWKGMEECKRQG 153 Query: 598 LVKSIGVSNFNSKQLERLLXHAXVKPVVNXVECHPYLNXKRLKEFCXXRGVXIXXYSP 771 L +SIG+SNFNS+Q+ RLL A +KPV N VE LN K L EFC + + +SP Sbjct: 154 LARSIGLSNFNSEQIARLLSSAKIKPVNNQVEVTMNLNQKPLIEFCKKHEITVTGFSP 211 Score = 116 bits (278), Expect = 1e-24 Identities = 57/119 (47%), Positives = 74/119 (62%), Gaps = 1/119 (0%) Frame = +1 Query: 418 CRRPWNNLNFQYLDLYLIHWP-QAYKEDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKE 594 C++ N+L Y+DLYLIHWP + Y + SGK+ SD DY++TWK ME ++ Sbjct: 354 CKQSLNDLGLDYIDLYLIHWPIRRYFRHNK----NASGKLLLSDTDYLETWKGMEECKRQ 409 Query: 595 GLVKSIGVSNFNSKQLERLLXHAXVKPVVNXVECHPYLNXKRLKEFCXXRGVXIXXYSP 771 GL +SIGVSNFNS+Q+ RLL A +KPV N VE LN K L EFC + + YSP Sbjct: 410 GLARSIGVSNFNSEQITRLLEAAKIKPVNNQVEVSLKLNQKALIEFCKKHDITVTGYSP 468 Score = 107 bits (257), Expect = 4e-22 Identities = 47/85 (55%), Positives = 63/85 (74%) Frame = +3 Query: 180 PXFGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIKEGVVTREDL 359 P GLGT+ SKPGEV +AVK AI++GYRH+D A+ Y NEKE+G AI KI +G + RED+ Sbjct: 15 PMIGLGTFLSKPGEVAEAVKYAIEVGYRHVDTAFFYENEKEIGSAIREKINDGTIKREDI 74 Query: 360 FITSKLWNTFHRPDLVRGALQETLE 434 F+T+KLW H+ D V A +++LE Sbjct: 75 FVTTKLWCNSHKEDEVVPACKKSLE 99 Score = 66.1 bits (154), Expect = 1e-09 Identities = 32/66 (48%), Positives = 42/66 (63%) Frame = +3 Query: 258 YRHIDCAYVYGNEKEVGEAITSKIKEGVVTREDLFITSKLWNTFHRPDLVRGALQETLEQ 437 YRHID AY+Y NEK +G AI KIK+G V REDLF+T+KL H+ V A +++L Sbjct: 301 YRHIDTAYLYDNEKYIGNAIREKIKDGTVKREDLFVTTKLSYYAHKESEVVPACKQSLND 360 Query: 438 SELSVL 455 L + Sbjct: 361 LGLDYI 366 >UniRef50_P15121 Cluster: Aldose reductase; n=72; Eumetazoa|Rep: Aldose reductase - Homo sapiens (Human) Length = 316 Score = 134 bits (324), Expect = 3e-30 Identities = 58/120 (48%), Positives = 80/120 (66%), Gaps = 2/120 (1%) Frame = +1 Query: 418 CRRPWNNLNFQYLDLYLIHWPQAYKEDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEG 597 C++ ++L YLDLYLIHWP +K FP D+SG + SD + +DTW AME LV EG Sbjct: 93 CQKTLSDLKLDYLDLYLIHWPTGFKPGKEFFPLDESGNVVPSDTNILDTWAAMEELVDEG 152 Query: 598 LVKSIGVSNFNSKQLERLLXHAXV--KPVVNXVECHPYLNXKRLKEFCXXRGVXIXXYSP 771 LVK+IG+SNFN Q+E +L + KP VN +ECHPYL ++L ++C +G+ + YSP Sbjct: 153 LVKAIGISNFNHLQVEMILNKPGLKYKPAVNQIECHPYLTQEKLIQYCQSKGIVVTAYSP 212 Score = 128 bits (310), Expect = 1e-28 Identities = 59/92 (64%), Positives = 70/92 (76%) Frame = +3 Query: 180 PXFGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIKEGVVTREDL 359 P GLGTWKS PG+VT+AVK AID+GYRHIDCA+VY NE EVG AI K++E VV RE+L Sbjct: 14 PILGLGTWKSPPGQVTEAVKVAIDVGYRHIDCAHVYQNENEVGVAIQEKLREQVVKREEL 73 Query: 360 FITSKLWNTFHRPDLVRGALQETLEQSELSVL 455 FI SKLW T+H LV+GA Q+TL +L L Sbjct: 74 FIVSKLWCTYHEKGLVKGACQKTLSDLKLDYL 105 >UniRef50_Q9VTL0 Cluster: CG6083-PA; n=4; Diptera|Rep: CG6083-PA - Drosophila melanogaster (Fruit fly) Length = 322 Score = 132 bits (318), Expect = 2e-29 Identities = 57/84 (67%), Positives = 69/84 (82%) Frame = +3 Query: 180 PXFGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIKEGVVTREDL 359 P GLGTW+S P VTQAVKDAIDIGYRH DCA++YGNE +VG A+ K+ EGVVTR++L Sbjct: 15 PMLGLGTWRSPPEVVTQAVKDAIDIGYRHFDCAHIYGNEAQVGAALREKMDEGVVTRDEL 74 Query: 360 FITSKLWNTFHRPDLVRGALQETL 431 FITSKLWNT H+PDLVR A + ++ Sbjct: 75 FITSKLWNTHHKPDLVRPACETSI 98 Score = 130 bits (315), Expect = 3e-29 Identities = 61/119 (51%), Positives = 78/119 (65%), Gaps = 2/119 (1%) Frame = +1 Query: 418 CRRPWNNLNFQYLDLYLIHWPQAYKEDG-SLFPT-DQSGKIQFSDVDYVDTWKAMEPLVK 591 C NL +YL+LYL+HWP AYK +L+PT + K F D+DYVDTW+AME LV Sbjct: 94 CETSIRNLGVKYLNLYLMHWPMAYKSGSDNLYPTCPDTNKAAFEDIDYVDTWRAMENLVD 153 Query: 592 EGLVKSIGVSNFNSKQLERLLXHAXVKPVVNXVECHPYLNXKRLKEFCXXRGVXIXXYS 768 EGL ++IGVSNFN +Q+ RLL A +KPVV +ECHPYL+ K L C + + YS Sbjct: 154 EGLCQAIGVSNFNEQQMNRLLSVAKLKPVVLQIECHPYLSQKPLITLCYDNAIAVTAYS 212 >UniRef50_Q8CI22 Cluster: 2310005E10Rik protein; n=30; Tetrapoda|Rep: 2310005E10Rik protein - Mus musculus (Mouse) Length = 316 Score = 130 bits (314), Expect = 5e-29 Identities = 58/115 (50%), Positives = 76/115 (66%), Gaps = 2/115 (1%) Frame = +1 Query: 433 NNLNFQYLDLYLIHWPQAYKEDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSI 612 ++L YLDLYLIHWPQ ++ PTD G I S ++D W+AME LV +GLVK++ Sbjct: 98 SDLKLDYLDLYLIHWPQGFQSGNVFLPTDDKGSILSSKYTFLDAWEAMEELVDQGLVKAL 157 Query: 613 GVSNFNSKQLERLLXHAXV--KPVVNXVECHPYLNXKRLKEFCXXRGVXIXXYSP 771 GVSNFN Q+ERLL + KPV N VECHPYL ++L ++C +G+ I YSP Sbjct: 158 GVSNFNHFQIERLLNKPGLKHKPVTNQVECHPYLTQEKLTQYCHSKGITITAYSP 212 Score = 124 bits (299), Expect = 3e-27 Identities = 63/111 (56%), Positives = 70/111 (63%) Frame = +3 Query: 180 PXFGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIKEGVVTREDL 359 P GLGTWKS P +V +AVK AID GYRHIDCAYVY NE EVGEAI KI+E V REDL Sbjct: 14 PIVGLGTWKSPPAKVREAVKVAIDAGYRHIDCAYVYQNESEVGEAIQEKIQEKAVKREDL 73 Query: 360 FITSKLWNTFHRPDLVRGALQETLEQSELSVLGSVPDTLAPGLQGRRLSLP 512 FI SKLW+TF LV+ A Q TL +L L G Q + LP Sbjct: 74 FIVSKLWSTFFEKSLVKKAFQNTLSDLKLDYLDLYLIHWPQGFQSGNVFLP 124 >UniRef50_Q9NAI5 Cluster: Putative uncharacterized protein; n=3; Caenorhabditis|Rep: Putative uncharacterized protein - Caenorhabditis elegans Length = 316 Score = 128 bits (308), Expect = 2e-28 Identities = 54/113 (47%), Positives = 74/113 (65%) Frame = +1 Query: 433 NNLNFQYLDLYLIHWPQAYKEDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSI 612 ++L Y+DL LIHWPQ Y E LFP ++GK+++SDVDY++TWKA E K G +SI Sbjct: 98 SDLQLSYVDLMLIHWPQGYAEGAELFPAGENGKMRYSDVDYLETWKAFEAAQKAGKCRSI 157 Query: 613 GVSNFNSKQLERLLXHAXVKPVVNXVECHPYLNXKRLKEFCXXRGVXIXXYSP 771 G+SNF Q++R+ A VKP VE HPY +L+EFC +G+ + YSP Sbjct: 158 GLSNFTHSQIQRVWDAAEVKPACLQVELHPYFTQVKLREFCKEKGIVVVGYSP 210 Score = 112 bits (269), Expect = 1e-23 Identities = 48/71 (67%), Positives = 57/71 (80%) Frame = +3 Query: 180 PXFGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIKEGVVTREDL 359 P GLGTW+SKPGEV A+K A+ GYRHIDCA+VY N+KEVGEA+ + EG V RE+L Sbjct: 14 PAIGLGTWQSKPGEVAAAIKTAVAAGYRHIDCAHVYQNQKEVGEALKEILDEGKVKREEL 73 Query: 360 FITSKLWNTFH 392 FITSK+WNTFH Sbjct: 74 FITSKVWNTFH 84 >UniRef50_UPI00015B56A3 Cluster: PREDICTED: similar to aldo-keto reductase; n=1; Nasonia vitripennis|Rep: PREDICTED: similar to aldo-keto reductase - Nasonia vitripennis Length = 321 Score = 122 bits (293), Expect = 2e-26 Identities = 53/118 (44%), Positives = 73/118 (61%) Frame = +1 Query: 418 CRRPWNNLNFQYLDLYLIHWPQAYKEDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEG 597 C+R L Y+DLYL+HWP +Y + +VDY++TW+ ME +K G Sbjct: 98 CKRSLKKLGLGYIDLYLVHWPFSYPILYQYIVLPTYNAVTLDEVDYIETWRGMEECIKLG 157 Query: 598 LVKSIGVSNFNSKQLERLLXHAXVKPVVNXVECHPYLNXKRLKEFCXXRGVXIXXYSP 771 L +SIGVSNFNS+QL RLL A +KPV+N +E H LN K+L+EFC + + + YSP Sbjct: 158 LTRSIGVSNFNSQQLTRLLESASIKPVMNQIELHINLNQKKLREFCASKSIAVTGYSP 215 Score = 101 bits (241), Expect = 3e-20 Identities = 48/94 (51%), Positives = 63/94 (67%), Gaps = 2/94 (2%) Frame = +3 Query: 180 PXFGLGTWK--SKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIKEGVVTRE 353 P GLGTW+ + P EV AVK AID GYRH DCA YGNE E+G+AI KI +GVV RE Sbjct: 17 PVLGLGTWQGGNDPDEVENAVKLAIDAGYRHFDCASFYGNEAEIGKAIQEKIDQGVVKRE 76 Query: 354 DLFITSKLWNTFHRPDLVRGALQETLEQSELSVL 455 DLF+ +K+WN + +LV A + +L++ L + Sbjct: 77 DLFVVTKVWNDERKQELVVAACKRSLKKLGLGYI 110 >UniRef50_A5KSS3 Cluster: Aldehyde reductase; n=1; candidate division TM7 genomosp. GTL1|Rep: Aldehyde reductase - candidate division TM7 genomosp. GTL1 Length = 299 Score = 122 bits (293), Expect = 2e-26 Identities = 55/120 (45%), Positives = 76/120 (63%) Frame = +1 Query: 412 VPCRRPWNNLNFQYLDLYLIHWPQAYKEDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVK 591 V CR+ N+L YLDLYLIHW A++ +L P D G +FS + +TW+AME LV+ Sbjct: 90 VACRKTLNDLGLDYLDLYLIHWGVAFEHGDNLEPLDDDGVAKFSFISMKETWQAMEELVE 149 Query: 592 EGLVKSIGVSNFNSKQLERLLXHAXVKPVVNXVECHPYLNXKRLKEFCXXRGVXIXXYSP 771 +GLVKS+GV+NF + L LL +A +KP V+ +E HPYL L FC + + + YSP Sbjct: 150 QGLVKSMGVANFTAPMLLDLLSYAKIKPAVHQIELHPYLAQNDLVAFCYSQNIAVTAYSP 209 Score = 102 bits (244), Expect = 1e-20 Identities = 50/92 (54%), Positives = 57/92 (61%) Frame = +3 Query: 180 PXFGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIKEGVVTREDL 359 P G GTW+ G V+ AI GYRHIDCA +YGNEKEVGE I I +GVV REDL Sbjct: 13 PLLGYGTWELPTGTTADLVETAIKAGYRHIDCAMIYGNEKEVGEGIRRTIDQGVVKREDL 72 Query: 360 FITSKLWNTFHRPDLVRGALQETLEQSELSVL 455 F+TSKLWNT H V A ++TL L L Sbjct: 73 FVTSKLWNTDHAQVDVGVACRKTLNDLGLDYL 104 >UniRef50_Q17DN1 Cluster: Aldo-keto reductase; n=1; Aedes aegypti|Rep: Aldo-keto reductase - Aedes aegypti (Yellowfever mosquito) Length = 284 Score = 121 bits (292), Expect = 2e-26 Identities = 54/90 (60%), Positives = 66/90 (73%) Frame = +1 Query: 502 SLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLXHAXVKPVV 681 +L P D GK+QFSDVDY+DTWKAME L+K G VKSIGVSNFNS+Q+ RLL +KPV Sbjct: 89 NLMPYDADGKLQFSDVDYIDTWKAMEKLLKTGKVKSIGVSNFNSEQITRLLAECEIKPVT 148 Query: 682 NXVECHPYLNXKRLKEFCXXRGVXIXXYSP 771 N VEC+P LN ++L EFC + + YSP Sbjct: 149 NQVECNPSLNQRKLTEFCKNLDITLTAYSP 178 Score = 101 bits (243), Expect = 2e-20 Identities = 48/71 (67%), Positives = 55/71 (77%), Gaps = 2/71 (2%) Frame = +3 Query: 180 PXFGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIKEGVVTREDL 359 P GLGTW SK GE +A+K AID GYRHID AY Y NEKEVGEAI +KI+EGVV REDL Sbjct: 17 PVLGLGTWLSKEGEGVEAIKAAIDAGYRHIDTAYFYQNEKEVGEAIRAKIEEGVVCREDL 76 Query: 360 FITSKL--WNT 386 F+T+K W+T Sbjct: 77 FVTTKFIDWDT 87 >UniRef50_P14550 Cluster: Alcohol dehydrogenase [NADP+]; n=44; Bilateria|Rep: Alcohol dehydrogenase [NADP+] - Homo sapiens (Human) Length = 325 Score = 121 bits (292), Expect = 2e-26 Identities = 53/117 (45%), Positives = 76/117 (64%) Frame = +1 Query: 421 RRPWNNLNFQYLDLYLIHWPQAYKEDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGL 600 R+ +L +YLDLYL+HWP A++ + FP + G I + Y +TWKA+E LV +GL Sbjct: 96 RKTLADLQLEYLDLYLMHWPYAFERGDNPFPKNADGTICYDSTHYKETWKALEALVAKGL 155 Query: 601 VKSIGVSNFNSKQLERLLXHAXVKPVVNXVECHPYLNXKRLKEFCXXRGVXIXXYSP 771 V+++G+SNFNS+Q++ +L A V+P V VECHPYL L C RG+ + YSP Sbjct: 156 VQALGLSNFNSRQIDDILSVASVRPAVLQVECHPYLAQNELIAHCQARGLEVTAYSP 212 Score = 116 bits (280), Expect = 6e-25 Identities = 53/93 (56%), Positives = 67/93 (72%), Gaps = 1/93 (1%) Frame = +3 Query: 180 PXFGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIKEG-VVTRED 356 P GLGTWKS+PG+V AVK A+ +GYRHIDCA +YGNE E+GEA+ + G V RE+ Sbjct: 15 PLIGLGTWKSEPGQVKAAVKYALSVGYRHIDCAAIYGNEPEIGEALKEDVGPGKAVPREE 74 Query: 357 LFITSKLWNTFHRPDLVRGALQETLEQSELSVL 455 LF+TSKLWNT H P+ V AL++TL +L L Sbjct: 75 LFVTSKLWNTKHHPEDVEPALRKTLADLQLEYL 107 >UniRef50_UPI0000588153 Cluster: PREDICTED: hypothetical protein; n=1; Strongylocentrotus purpuratus|Rep: PREDICTED: hypothetical protein - Strongylocentrotus purpuratus Length = 333 Score = 120 bits (290), Expect = 4e-26 Identities = 56/118 (47%), Positives = 75/118 (63%), Gaps = 2/118 (1%) Frame = +1 Query: 424 RPWNNLNFQYLDLYLIHWPQAYKEDGS--LFPTDQSGKIQFSDVDYVDTWKAMEPLVKEG 597 R +L Y+DLY++HWP ++ G +FP ++G I +SDV Y++TW AME LVK G Sbjct: 95 RSLTDLQLDYIDLYIMHWPLGFQNLGPTVMFPRTETGDIVYSDVHYLETWSAMEDLVKTG 154 Query: 598 LVKSIGVSNFNSKQLERLLXHAXVKPVVNXVECHPYLNXKRLKEFCXXRGVXIXXYSP 771 KS+G+SNFNSKQL+ +L H+ V P V VE HP+L L FC R V + YSP Sbjct: 155 KCKSLGLSNFNSKQLDDVLQHSTVPPSVLQVESHPFLPQVELLNFCRERSVVVSAYSP 212 Score = 98.3 bits (234), Expect = 2e-19 Identities = 44/92 (47%), Positives = 58/92 (63%) Frame = +3 Query: 180 PXFGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIKEGVVTREDL 359 P GLGTWK K EV A+ A+D GYRH DCA +YGNEKEVG A+ ++ + RED+ Sbjct: 14 PLVGLGTWKLKADEVAGAIGAAVDAGYRHFDCALIYGNEKEVGVALREAMQRLGLKREDV 73 Query: 360 FITSKLWNTFHRPDLVRGALQETLEQSELSVL 455 FIT+K+WNTFH + V +L +L + Sbjct: 74 FITTKVWNTFHAKEDVAECFNRSLTDLQLDYI 105 >UniRef50_Q17DN0 Cluster: Aldo-keto reductase; n=5; Culicidae|Rep: Aldo-keto reductase - Aedes aegypti (Yellowfever mosquito) Length = 324 Score = 120 bits (288), Expect = 7e-26 Identities = 59/116 (50%), Positives = 75/116 (64%), Gaps = 4/116 (3%) Frame = +1 Query: 436 NLNFQYLDLYLIHWPQAYKEDG----SLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLV 603 +L Y+DL+LIH P Y+ +G P D +G + SD DYVDTWKAME L++ G V Sbjct: 103 HLGLDYVDLFLIHMPFGYEFNGWDPEKRTPLDDNGNVLCSDDDYVDTWKAMEKLLESGRV 162 Query: 604 KSIGVSNFNSKQLERLLXHAXVKPVVNXVECHPYLNXKRLKEFCXXRGVXIXXYSP 771 SIGVSNFNS+QLER+L + VKPV N VEC +N K L EFC R + + +SP Sbjct: 163 HSIGVSNFNSEQLERILANCRVKPVTNQVECSARINQKLLIEFCMERDIVVTAHSP 218 Score = 105 bits (252), Expect = 2e-21 Identities = 52/85 (61%), Positives = 61/85 (71%) Frame = +3 Query: 180 PXFGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIKEGVVTREDL 359 P GLGT SK E +AV AID G+RHID AY Y NE VG AI +KI+EGVVTRE+L Sbjct: 18 PAIGLGTSMSKGDECCKAVMTAIDEGFRHIDTAYNYRNEDVVGRAIRAKIEEGVVTREEL 77 Query: 360 FITSKLWNTFHRPDLVRGALQETLE 434 F+T+KLWNTFH PD V A ++LE Sbjct: 78 FVTTKLWNTFHHPDHVPMAFGKSLE 102 >UniRef50_A2QBD7 Cluster: Catalytic activity: an alcohol + NADP(+) <=> an aldehyde + NADPH; n=4; Trichocomaceae|Rep: Catalytic activity: an alcohol + NADP(+) <=> an aldehyde + NADPH - Aspergillus niger Length = 323 Score = 118 bits (285), Expect = 2e-25 Identities = 52/112 (46%), Positives = 71/112 (63%) Frame = +1 Query: 436 NLNFQYLDLYLIHWPQAYKEDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIG 615 +L YLDLYL+HWP A+K FP + G +++DY+ T++AME L+ G V++IG Sbjct: 97 DLGVAYLDLYLMHWPCAFKGGDKWFPLNDDGVFDLANIDYITTYRAMEKLLATGKVRAIG 156 Query: 616 VSNFNSKQLERLLXHAXVKPVVNXVECHPYLNXKRLKEFCXXRGVXIXXYSP 771 VSNFN ++LE LL V P VN +E HPYL L +FC +G+ I YSP Sbjct: 157 VSNFNIRRLEELLGQVSVVPAVNQIEAHPYLQQPDLLQFCQSKGILIEAYSP 208 Score = 93.1 bits (221), Expect = 9e-18 Identities = 48/92 (52%), Positives = 60/92 (65%) Frame = +3 Query: 180 PXFGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIKEGVVTREDL 359 P G GTW++KP EV AV+ A+ GYRHIDCA +Y NE EVG I K G V RE++ Sbjct: 16 PAVGFGTWQAKPLEVENAVEVALREGYRHIDCAAIYRNETEVGNGIR---KSG-VPREEI 71 Query: 360 FITSKLWNTFHRPDLVRGALQETLEQSELSVL 455 FIT KLWNT H P+ V AL +TL+ ++ L Sbjct: 72 FITGKLWNTKHAPEDVEPALDKTLQDLGVAYL 103 >UniRef50_UPI000065D0BD Cluster: Homolog of Homo sapiens "AKR1B1 protein.; n=1; Takifugu rubripes|Rep: Homolog of Homo sapiens "AKR1B1 protein. - Takifugu rubripes Length = 330 Score = 117 bits (282), Expect = 3e-25 Identities = 56/91 (61%), Positives = 63/91 (69%) Frame = +3 Query: 174 LFPXFGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIKEGVVTRE 353 L P GLGTWKS G T+AVK AI GYRHID AYVY NE EVG + + I +GVV RE Sbjct: 12 LMPVLGLGTWKSGKGVTTEAVKVAIGAGYRHIDTAYVYENETEVGAGVQAMIDQGVVKRE 71 Query: 354 DLFITSKLWNTFHRPDLVRGALQETLEQSEL 446 +LFI SKLW TFH P LVRGA ++TL L Sbjct: 72 ELFIVSKLWCTFHTPSLVRGACEKTLSSLNL 102 Score = 91.5 bits (217), Expect = 3e-17 Identities = 48/143 (33%), Positives = 77/143 (53%), Gaps = 26/143 (18%) Frame = +1 Query: 418 CRRPWNNLNFQYLDLYLIHWPQA------------------YKEDGSL------FPTDQS 525 C + ++LN Y+DLYL+H+P +++ L FP D+ Sbjct: 93 CEKTLSSLNLDYVDLYLMHFPMGALSATLDLTSLTDVIPTVFRDFSPLQPGEDPFPLDEH 152 Query: 526 GKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLXHAXV--KPVVNXVECH 699 ++ ++DTW+AME LV +GL K+IG+SNFN Q+E +L + KP N +ECH Sbjct: 153 NQLICDGTSFLDTWEAMEELVDDGLAKAIGISNFNKDQIEAVLNKPGLKHKPATNQIECH 212 Query: 700 PYLNXKRLKEFCXXRGVXIXXYS 768 P+LN ++L FC RG+ + ++ Sbjct: 213 PHLNQEKLIHFCRSRGISVTAFA 235 >UniRef50_Q96JD6-2 Cluster: Isoform 2 of Q96JD6 ; n=4; Catarrhini|Rep: Isoform 2 of Q96JD6 - Homo sapiens (Human) Length = 263 Score = 117 bits (282), Expect = 3e-25 Identities = 53/92 (57%), Positives = 67/92 (72%) Frame = +3 Query: 180 PXFGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIKEGVVTREDL 359 P GL +WK+ PG+VT+AVK+AID GYRH DCAY Y NE+EVG I KIKEG V REDL Sbjct: 5 PAVGLSSWKASPGKVTEAVKEAIDAGYRHFDCAYFYHNEREVGAGIRCKIKEGAVRREDL 64 Query: 360 FITSKLWNTFHRPDLVRGALQETLEQSELSVL 455 FI +KLW T H+ LV A +++L+ +L+ L Sbjct: 65 FIATKLWCTCHKKSLVETACRKSLKALKLNYL 96 Score = 81.4 bits (192), Expect = 3e-14 Identities = 48/112 (42%), Positives = 61/112 (54%), Gaps = 21/112 (18%) Frame = +1 Query: 418 CRRPWNNLNFQYLDLYLIHWPQAYKEDGSLF-------------------PTDQSGKIQF 540 CR+ L YLDLYLIHWP +K + P D+S + Sbjct: 84 CRKSLKALKLNYLDLYLIHWPMGFKPPHPEWIMSCSELSFCLSHPRVQDLPLDESNMVIP 143 Query: 541 SDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLXHAXV--KPVVNXV 690 SD D++DTW+AME LV GLVK+IGVSNFN +QLERLL + KP+ N + Sbjct: 144 SDTDFLDTWEAMEDLVITGLVKNIGVSNFNHEQLERLLNKPGLRFKPLTNQI 195 >UniRef50_Q7QVQ9 Cluster: GLP_302_44328_45269; n=1; Giardia lamblia ATCC 50803|Rep: GLP_302_44328_45269 - Giardia lamblia ATCC 50803 Length = 313 Score = 117 bits (282), Expect = 3e-25 Identities = 53/120 (44%), Positives = 73/120 (60%), Gaps = 2/120 (1%) Frame = +1 Query: 418 CRRPWNNLNFQYLDLYLIHWPQAYKED--GSLFPTDQSGKIQFSDVDYVDTWKAMEPLVK 591 C++ ++L YLDL+L+HWP A+ + G LFP D G+ V DTW+AME LV+ Sbjct: 86 CKKTMSDLQVDYLDLFLVHWPLAFVRNDVGDLFPKDAEGRAMLEKVPLADTWRAMEQLVE 145 Query: 592 EGLVKSIGVSNFNSKQLERLLXHAXVKPVVNXVECHPYLNXKRLKEFCXXRGVXIXXYSP 771 EGLVK IGVSN+ L LL +A +KP+VN +E HP+ +FC G+ + YSP Sbjct: 146 EGLVKHIGVSNYTVPLLADLLNYAKIKPLVNQIEIHPWHPNDATVKFCLDNGIGVTAYSP 205 Score = 94.7 bits (225), Expect = 3e-18 Identities = 44/94 (46%), Positives = 60/94 (63%), Gaps = 2/94 (2%) Frame = +3 Query: 180 PXFGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIKEGV--VTRE 353 P G GTW++ P V AV+ A+ GYRHIDCAYVY NE+ +G A K+ + RE Sbjct: 5 PRLGFGTWQAPPEAVQTAVETALMTGYRHIDCAYVYQNEEAIGRAFGKIFKDASSGIKRE 64 Query: 354 DLFITSKLWNTFHRPDLVRGALQETLEQSELSVL 455 D++ITSKLWN HRP+LVR ++T+ ++ L Sbjct: 65 DVWITSKLWNYNHRPELVREQCKKTMSDLQVDYL 98 >UniRef50_Q96JD6 Cluster: Aldo-keto reductase family 1 member C-like protein 2; n=37; Euteleostomi|Rep: Aldo-keto reductase family 1 member C-like protein 2 - Homo sapiens (Human) Length = 320 Score = 117 bits (282), Expect = 3e-25 Identities = 53/92 (57%), Positives = 67/92 (72%) Frame = +3 Query: 180 PXFGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIKEGVVTREDL 359 P GL +WK+ PG+VT+AVK+AID GYRH DCAY Y NE+EVG I KIKEG V REDL Sbjct: 5 PAVGLSSWKASPGKVTEAVKEAIDAGYRHFDCAYFYHNEREVGAGIRCKIKEGAVRREDL 64 Query: 360 FITSKLWNTFHRPDLVRGALQETLEQSELSVL 455 FI +KLW T H+ LV A +++L+ +L+ L Sbjct: 65 FIATKLWCTCHKKSLVETACRKSLKALKLNYL 96 Score = 113 bits (271), Expect = 8e-24 Identities = 62/139 (44%), Positives = 76/139 (54%), Gaps = 21/139 (15%) Frame = +1 Query: 418 CRRPWNNLNFQYLDLYLIHWPQAYKEDGSLF-------------------PTDQSGKIQF 540 CR+ L YLDLYLIHWP +K + P D+S + Sbjct: 84 CRKSLKALKLNYLDLYLIHWPMGFKPPHPEWIMSCSELSFCLSHPRVQDLPLDESNMVIP 143 Query: 541 SDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLXHAXV--KPVVNXVECHPYLNX 714 SD D++DTW+AME LV GLVK+IGVSNFN +QLERLL + KP+ N +ECHPYL Sbjct: 144 SDTDFLDTWEAMEDLVITGLVKNIGVSNFNHEQLERLLNKPGLRFKPLTNQIECHPYLTQ 203 Query: 715 KRLKEFCXXRGVXIXXYSP 771 K L FC R V + Y P Sbjct: 204 KNLISFCQSRDVSVTAYRP 222 >UniRef50_Q0VGY1 Cluster: 3-alpha-hydroxysteroid dehydrogenase; n=13; Tetrapoda|Rep: 3-alpha-hydroxysteroid dehydrogenase - Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) Length = 324 Score = 116 bits (279), Expect = 8e-25 Identities = 54/113 (47%), Positives = 71/113 (62%), Gaps = 2/113 (1%) Frame = +1 Query: 436 NLNFQYLDLYLIHWPQAYKEDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIG 615 +L Y+DL++IH P +K LFP D++GK + + D DTWKA+E GLV+SIG Sbjct: 106 DLQLDYMDLFIIHMPMEFKPGDDLFPADENGKFIYHNTDLRDTWKALEKCKDAGLVRSIG 165 Query: 616 VSNFNSKQLERLLXHAXV--KPVVNXVECHPYLNXKRLKEFCXXRGVXIXXYS 768 VSNFN KQLE +L + KPV N VECH YLN +L EFC + + + YS Sbjct: 166 VSNFNHKQLELILNMPGLKYKPVCNQVECHVYLNQSKLLEFCKSKDIVLVGYS 218 Score = 101 bits (242), Expect = 2e-20 Identities = 47/95 (49%), Positives = 64/95 (67%), Gaps = 3/95 (3%) Frame = +3 Query: 180 PXFGLGTW---KSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIKEGVVTR 350 P G GT+ K + K AID+GYRHIDCA++YGNE+EVG AI +KI +G V R Sbjct: 18 PVIGFGTYAPPKFPKSLAEEGTKVAIDVGYRHIDCAFLYGNEEEVGRAIRAKIADGTVKR 77 Query: 351 EDLFITSKLWNTFHRPDLVRGALQETLEQSELSVL 455 ED+F T KLW+T H P+ VR AL+++L+ +L + Sbjct: 78 EDVFYTGKLWSTSHTPERVRPALEKSLKDLQLDYM 112 >UniRef50_Q7QK25 Cluster: ENSANGP00000019775; n=2; Anopheles gambiae str. PEST|Rep: ENSANGP00000019775 - Anopheles gambiae str. PEST Length = 319 Score = 114 bits (275), Expect = 2e-24 Identities = 58/122 (47%), Positives = 80/122 (65%), Gaps = 5/122 (4%) Frame = +1 Query: 421 RRPWNNLNFQYLDLYLIHWPQAYKEDG----SLFPTDQSGKIQFSDVDYVDTWKAMEPLV 588 RR ++ L+ Y+DL+L+H P + G + P D +G + FSDVDYV+TWKAME LV Sbjct: 97 RRSFDMLDIGYIDLFLMHSPMGVQFSGYEYADMQPKDAAGNMLFSDVDYVETWKAMEKLV 156 Query: 589 KEG-LVKSIGVSNFNSKQLERLLXHAXVKPVVNXVECHPYLNXKRLKEFCXXRGVXIXXY 765 G V+SIG+SNFNS+Q+ER+L A VKPV N VE +P + ++L FC RG+ + Y Sbjct: 157 TAGGRVRSIGLSNFNSEQIERILQIATVKPVNNQVEANPGYDQRKLIAFCQARGITVTAY 216 Query: 766 SP 771 P Sbjct: 217 GP 218 Score = 105 bits (252), Expect = 2e-21 Identities = 44/92 (47%), Positives = 64/92 (69%) Frame = +3 Query: 180 PXFGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIKEGVVTREDL 359 P G GT+ ++ G+ + VK AID+GYRHID A++Y NE E+G+AI KI EGV+ RED+ Sbjct: 17 PVLGYGTYLAQKGQCVELVKKAIDLGYRHIDTAFLYENEVEIGQAIRDKIAEGVIRREDV 76 Query: 360 FITSKLWNTFHRPDLVRGALQETLEQSELSVL 455 F+T+KLWNTFH P V A + + + ++ + Sbjct: 77 FVTTKLWNTFHDPQHVEEAFRRSFDMLDIGYI 108 >UniRef50_Q5BKE9 Cluster: LOC594893 protein; n=5; Xenopus tropicalis|Rep: LOC594893 protein - Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) Length = 345 Score = 114 bits (274), Expect = 3e-24 Identities = 52/111 (46%), Positives = 69/111 (62%), Gaps = 2/111 (1%) Frame = +1 Query: 439 LNFQYLDLYLIHWPQAYKEDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGV 618 L Y+DLYLIH P ++K LFP ++ G F D + TW+A+E GLVKSIGV Sbjct: 128 LQMDYVDLYLIHMPMSFKPAEELFPKNEDGTCAFDQPDLLQTWQALEECRDAGLVKSIGV 187 Query: 619 SNFNSKQLERLLXHAXV--KPVVNXVECHPYLNXKRLKEFCXXRGVXIXXY 765 SNFN +QLE +L + KPV N +ECHPYLN K++ EFC + + + Y Sbjct: 188 SNFNRRQLEMILNKPGLKYKPVCNQIECHPYLNQKQMLEFCKSKDIVVVAY 238 Score = 95.5 bits (227), Expect = 2e-18 Identities = 44/79 (55%), Positives = 57/79 (72%) Frame = +3 Query: 195 GTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIKEGVVTREDLFITSK 374 GT KS +V A K A+D+GYRH+D A++Y +E VG+A K +G + REDLF TSK Sbjct: 47 GTEKSFIDDVRVATKMALDLGYRHVDGAFLYSSETGVGQAFREKFADGTLKREDLFYTSK 106 Query: 375 LWNTFHRPDLVRGALQETL 431 LWNTFH+P LVR AL++TL Sbjct: 107 LWNTFHQPHLVRPALEKTL 125 >UniRef50_Q96UH3 Cluster: Aldehyde reductase; n=13; Pezizomycotina|Rep: Aldehyde reductase - Coccidioides posadasii Length = 314 Score = 114 bits (274), Expect = 3e-24 Identities = 50/111 (45%), Positives = 68/111 (61%) Frame = +1 Query: 436 NLNFQYLDLYLIHWPQAYKEDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIG 615 NL YLDLYL+HWP A+ +FP D G + D+DYVDT+KAME LVK G K+IG Sbjct: 97 NLEIDYLDLYLMHWPAAFAPGDDMFPKDSQGNSKTVDIDYVDTYKAMEKLVKSGKTKAIG 156 Query: 616 VSNFNSKQLERLLXHAXVKPVVNXVECHPYLNXKRLKEFCXXRGVXIXXYS 768 +SNF+ ++ERLL + P V +E HP+L E+ +G+ + YS Sbjct: 157 ISNFSKGEMERLLESCSIVPAVMQMELHPWLQQNDFVEWLKSKGIHVTQYS 207 Score = 81.4 bits (192), Expect = 3e-14 Identities = 44/106 (41%), Positives = 60/106 (56%), Gaps = 4/106 (3%) Frame = +3 Query: 180 PXFGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIKEGVVTREDL 359 P G GTW+ + + AV A+ GYRHID A VYG EK +G A+ ++R++L Sbjct: 17 PAIGFGTWQDENAQ-EDAVLTALSAGYRHIDTAAVYGTEKAIGRALA----RSRLSRDEL 71 Query: 360 FITSKLWNTFHRPDLVRGALQETLEQSELSVLGSV----PDTLAPG 485 FITSKLWN HRP+ V A+ ++L+ E+ L P APG Sbjct: 72 FITSKLWNNKHRPEDVEQAIDQSLKNLEIDYLDLYLMHWPAAFAPG 117 >UniRef50_Q7JVH6 Cluster: LD24696p; n=2; Sophophora|Rep: LD24696p - Drosophila melanogaster (Fruit fly) Length = 311 Score = 113 bits (271), Expect = 8e-24 Identities = 52/118 (44%), Positives = 74/118 (62%) Frame = +1 Query: 418 CRRPWNNLNFQYLDLYLIHWPQAYKEDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEG 597 CR +NL +Y+DLYL+H P K ++ G ++ +DVDY+DTW+ ME LV G Sbjct: 96 CRLSLSNLGLEYVDLYLMHMPVGQKFHND---SNVHGTLELTDVDYLDTWREMEKLVDLG 152 Query: 598 LVKSIGVSNFNSKQLERLLXHAXVKPVVNXVECHPYLNXKRLKEFCXXRGVXIXXYSP 771 L +SIG+SNFN+ Q ER+L + ++PVVN VECHP ++L+E G+ I Y P Sbjct: 153 LTRSIGLSNFNAAQTERVLANCRIRPVVNQVECHPGFQQRQLREHAKRHGLVICAYCP 210 Score = 97.9 bits (233), Expect = 3e-19 Identities = 44/84 (52%), Positives = 59/84 (70%) Frame = +3 Query: 180 PXFGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIKEGVVTREDL 359 P GLGTWKS + + + A+D+GYRH+D A+VY NE EVG+AI+ KI EGVVTRE++ Sbjct: 17 PTLGLGTWKSFESDAYHSTRHALDVGYRHLDTAFVYENEAEVGQAISEKIAEGVVTREEV 76 Query: 360 FITSKLWNTFHRPDLVRGALQETL 431 F+T+KL H P LV A + +L Sbjct: 77 FVTTKLGGIHHDPALVERACRLSL 100 >UniRef50_Q2S340 Cluster: Aldehyde reductase; n=10; Bacteria|Rep: Aldehyde reductase - Salinibacter ruber (strain DSM 13855) Length = 321 Score = 112 bits (270), Expect = 1e-23 Identities = 49/92 (53%), Positives = 63/92 (68%) Frame = +3 Query: 180 PXFGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIKEGVVTREDL 359 P GLGTWKS PGEV +AV A++ GYRH+DCA +Y NE EVG A++ G + R+D+ Sbjct: 13 PMIGLGTWKSPPGEVYEAVTTALEAGYRHVDCAPIYKNETEVGAALSDSFDAGGIRRDDV 72 Query: 360 FITSKLWNTFHRPDLVRGALQETLEQSELSVL 455 ++TSKLWN H PD VR AL++TL L L Sbjct: 73 WVTSKLWNNAHHPDDVRPALEQTLSDLRLDAL 104 Score = 91.9 bits (218), Expect = 2e-17 Identities = 47/113 (41%), Positives = 61/113 (53%) Frame = +1 Query: 433 NNLNFQYLDLYLIHWPQAYKEDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSI 612 ++L LDLYLIHWP A + + FP + V +TW AME L K+GLV+ I Sbjct: 97 SDLRLDALDLYLIHWPVALQPEVD-FPESPDDFVSPEAVPLTETWAAMEALKKDGLVRHI 155 Query: 613 GVSNFNSKQLERLLXHAXVKPVVNXVECHPYLNXKRLKEFCXXRGVXIXXYSP 771 GVSNF+ L+ +L V+P +N VE HPYL L F + I YSP Sbjct: 156 GVSNFSVPNLQMILDAGEVRPEMNQVEMHPYLPQPELVSFAEAHNIPITAYSP 208 >UniRef50_A7SIT3 Cluster: Predicted protein; n=1; Nematostella vectensis|Rep: Predicted protein - Nematostella vectensis Length = 323 Score = 112 bits (270), Expect = 1e-23 Identities = 55/118 (46%), Positives = 74/118 (62%) Frame = +1 Query: 418 CRRPWNNLNFQYLDLYLIHWPQAYKEDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEG 597 C+ NL YLDLYLIH P A+K+ L + G I ++ +TW+AME LV +G Sbjct: 96 CQATLKNLQLDYLDLYLIHIPVAFKKGVRLPHSIAEGIIGYTPEGVQNTWQAMEGLVAKG 155 Query: 598 LVKSIGVSNFNSKQLERLLXHAXVKPVVNXVECHPYLNXKRLKEFCXXRGVXIXXYSP 771 L K+IGVSNF+ K+L +LL A + P N VE HPYL ++LKEFC +G+ + YSP Sbjct: 156 LCKAIGVSNFSVKRLNKLLETASIVPACNQVELHPYLPQEKLKEFCDSKGILLTAYSP 213 Score = 107 bits (257), Expect = 4e-22 Identities = 50/92 (54%), Positives = 63/92 (68%) Frame = +3 Query: 180 PXFGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIKEGVVTREDL 359 P LGTW+S EV AV+ AI++GYRHIDCA +YGNE E+GEA++ + EG V RE+L Sbjct: 17 PAMALGTWQSSKEEVGNAVRLAIELGYRHIDCAEIYGNEGEIGEALSEVLTEGKVKREEL 76 Query: 360 FITSKLWNTFHRPDLVRGALQETLEQSELSVL 455 F+TSKLW H PD V A Q TL+ +L L Sbjct: 77 FVTSKLWCDSHHPDDVLPACQATLKNLQLDYL 108 >UniRef50_Q55FL3 Cluster: Aldo-keto reductase; n=2; Dictyostelium discoideum AX4|Rep: Aldo-keto reductase - Dictyostelium discoideum AX4 Length = 321 Score = 111 bits (268), Expect = 2e-23 Identities = 58/123 (47%), Positives = 75/123 (60%), Gaps = 5/123 (4%) Frame = +1 Query: 418 CRRPWNNLNFQYLDLYLIHWPQAYKEDGSLFPT-----DQSGKIQFSDVDYVDTWKAMEP 582 C + +L YLDLYLIHWP A++ L T DQ+G + V +TW+ ME Sbjct: 106 CVKTIEDLGIGYLDLYLIHWPIAFENSNPLGLTIEPLRDQNGNPIIAPVSIRETWQEMEK 165 Query: 583 LVKEGLVKSIGVSNFNSKQLERLLXHAXVKPVVNXVECHPYLNXKRLKEFCXXRGVXIXX 762 LV+ GLVKSIGVSNFN + L LL +A +KPVVN VE HPYL +L+E+C + + Sbjct: 166 LVELGLVKSIGVSNFNVQNLVDLLTYAKIKPVVNQVEIHPYLTQFKLQEYCDKYEIKLVA 225 Query: 763 YSP 771 YSP Sbjct: 226 YSP 228 Score = 89.8 bits (213), Expect = 8e-17 Identities = 44/93 (47%), Positives = 59/93 (63%), Gaps = 1/93 (1%) Frame = +3 Query: 180 PXFGLGTWKSK-PGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIKEGVVTRED 356 P GLGT+ S+ PGEV A+ +A+ GYRHID A YGNEK +G ++ KEG + RED Sbjct: 26 PSIGLGTYYSENPGEVGDAINNALKNGYRHIDGAAFYGNEKVIGNSLKEIFKEGEIKRED 85 Query: 357 LFITSKLWNTFHRPDLVRGALQETLEQSELSVL 455 +F TSKLWN+ H +LV +T+E + L Sbjct: 86 IFYTSKLWNSCHNSNLVVKHCVKTIEDLGIGYL 118 >UniRef50_Q7ZWA4 Cluster: Zgc:56622; n=6; cellular organisms|Rep: Zgc:56622 - Danio rerio (Zebrafish) (Brachydanio rerio) Length = 289 Score = 110 bits (265), Expect = 4e-23 Identities = 53/114 (46%), Positives = 73/114 (64%), Gaps = 1/114 (0%) Frame = +1 Query: 433 NNLNFQYLDLYLIHWPQAYKEDGS-LFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKS 609 ++L YLD YL+H+P K+ G LFP ++ GKI +D+DYVD W+ ME L G VKS Sbjct: 72 SDLQLDYLDQYLVHFPVGLKKVGDELFP-ERDGKILTTDIDYVDVWRGMEALKATGKVKS 130 Query: 610 IGVSNFNSKQLERLLXHAXVKPVVNXVECHPYLNXKRLKEFCXXRGVXIXXYSP 771 IGVSNF +Q++RLL A + P VN VE HPYL L ++C + + + +SP Sbjct: 131 IGVSNFTMEQIDRLLSVAKIPPAVNQVELHPYLVQSDLIDYCKSKNIALTAHSP 184 Score = 76.6 bits (180), Expect = 8e-13 Identities = 34/76 (44%), Positives = 50/76 (65%) Frame = +3 Query: 228 QAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIKEGVVTREDLFITSKLWNTFHRPDLV 407 +A + AI GYRHID A+ Y NE +VG AI +KI++G++ R+D+FI SKLW T H P+ + Sbjct: 4 RACEAAIAAGYRHIDTAFCYRNEVDVGMAIQNKIQQGIIRRQDMFIVSKLWGTHHAPEDI 63 Query: 408 RGALQETLEQSELSVL 455 ++L +L L Sbjct: 64 PVCFNKSLSDLQLDYL 79 >UniRef50_Q8K023 Cluster: Aldo-keto reductase family 1 member C18; n=72; Tetrapoda|Rep: Aldo-keto reductase family 1 member C18 - Mus musculus (Mouse) Length = 323 Score = 110 bits (265), Expect = 4e-23 Identities = 53/111 (47%), Positives = 66/111 (59%), Gaps = 2/111 (1%) Frame = +1 Query: 439 LNFQYLDLYLIHWPQAYKEDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGV 618 LN Y+DLYLIH+P + K L P D+ G + F VD DTW+AME GL KSIGV Sbjct: 106 LNLDYVDLYLIHFPVSLKPGNELLPKDEHGNLIFDTVDLCDTWEAMEKCKDAGLAKSIGV 165 Query: 619 SNFNSKQLERLLXHAXV--KPVVNXVECHPYLNXKRLKEFCXXRGVXIXXY 765 SNFN +QLE +L + KPV N VECH YLN +L +C + + Y Sbjct: 166 SNFNRRQLEMILNKPGLKYKPVCNQVECHLYLNQSKLLAYCKMNDIVLVAY 216 Score = 98.7 bits (235), Expect = 2e-19 Identities = 49/109 (44%), Positives = 73/109 (66%), Gaps = 7/109 (6%) Frame = +3 Query: 180 PXFGLGTWKSKPG---EVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIKEGVVTR 350 P G GT+ ++ + ++ K AID+G+ HIDC+++Y NE+E+G+AI SKI++G V R Sbjct: 17 PVLGFGTYATEEHLKKKSMESTKIAIDVGFCHIDCSHLYQNEEEIGQAILSKIEDGTVKR 76 Query: 351 EDLFITSKLWNTFHRPDLVRGALQETLEQSELS----VLGSVPDTLAPG 485 ED+F TSKLW+T HRP+LVR +L+ +L + L L P +L PG Sbjct: 77 EDIFYTSKLWSTSHRPELVRPSLENSLRKLNLDYVDLYLIHFPVSLKPG 125 >UniRef50_Q54B70 Cluster: Aldehyde reductase; n=2; Dictyostelium discoideum|Rep: Aldehyde reductase - Dictyostelium discoideum AX4 Length = 297 Score = 110 bits (264), Expect = 5e-23 Identities = 55/93 (59%), Positives = 64/93 (68%), Gaps = 1/93 (1%) Frame = +3 Query: 180 PXFGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKI-KEGVVTRED 356 P G GTWK++ V +AV+ A+D GYRHIDCA VY NEKEVGEA T K E V RED Sbjct: 14 PLVGFGTWKAETTLVGKAVEVALDAGYRHIDCAAVYLNEKEVGEAFTKKFTTEATVKRED 73 Query: 357 LFITSKLWNTFHRPDLVRGALQETLEQSELSVL 455 +FITSKLWNTFH+ + VR AL+ TL L L Sbjct: 74 VFITSKLWNTFHKKEHVRPALERTLSDLGLQYL 106 Score = 106 bits (254), Expect = 9e-22 Identities = 53/116 (45%), Positives = 71/116 (61%) Frame = +1 Query: 424 RPWNNLNFQYLDLYLIHWPQAYKEDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLV 603 R ++L QYLDLYL+HWP A++ + T SG Q V +TW+ ME LV GLV Sbjct: 96 RTLSDLGLQYLDLYLVHWPVAFEYTSNDIQT--SGSTQ-EFVSIRETWEEMEKLVDAGLV 152 Query: 604 KSIGVSNFNSKQLERLLXHAXVKPVVNXVECHPYLNXKRLKEFCXXRGVXIXXYSP 771 KSIG+SNFN + L +L +A +KP N VE HP+L+ LK+FC + + YSP Sbjct: 153 KSIGLSNFNVQGLMEVLSYARIKPAANQVELHPFLSQPELKKFCDKHNIHLTAYSP 208 >UniRef50_UPI0000E4A7CE Cluster: PREDICTED: similar to LOC553452 protein; n=6; Strongylocentrotus purpuratus|Rep: PREDICTED: similar to LOC553452 protein - Strongylocentrotus purpuratus Length = 321 Score = 109 bits (263), Expect = 7e-23 Identities = 54/120 (45%), Positives = 73/120 (60%), Gaps = 2/120 (1%) Frame = +1 Query: 418 CRRPWNNLNFQYLDLYLIHWPQAYKEDGSLFPTDQSGKIQFSD-VDYVDTWKAMEPLVKE 594 CR+ ++L YLDL+LIH P + FP D +G D +DYVDTW+ ME LV + Sbjct: 96 CRQSLSDLGLAYLDLFLIHCPTSAVGGKGPFPMDDNGLFIGDDTIDYVDTWRIMESLVDK 155 Query: 595 GLVKSIGVSNFNSKQLERLLXHAXVKPVVN-XVECHPYLNXKRLKEFCXXRGVXIXXYSP 771 GLV++IGVSNF Q++R+L P+ N VECHP+L L EFC +G+ + YSP Sbjct: 156 GLVRAIGVSNFTVAQIQRVLDLPPKYPIANVQVECHPFLAQNELIEFCKKQGITVTAYSP 215 Score = 99 bits (238), Expect = 7e-20 Identities = 46/92 (50%), Positives = 61/92 (66%) Frame = +3 Query: 180 PXFGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIKEGVVTREDL 359 P G GTW+ KP EV + ++ AID GYRHID A +YGNEK VG+ I +KI +G + REDL Sbjct: 17 PLLGFGTWQIKPEEVGRVIETAIDCGYRHIDEASLYGNEKGVGDGIKAKIDDGTIKREDL 76 Query: 360 FITSKLWNTFHRPDLVRGALQETLEQSELSVL 455 F+TSKLW T P V + +++L L+ L Sbjct: 77 FVTSKLWVTDSHPSRVEPSCRQSLSDLGLAYL 108 >UniRef50_Q2V420 Cluster: Uncharacterized protein At2g37770.1; n=1; Arabidopsis thaliana|Rep: Uncharacterized protein At2g37770.1 - Arabidopsis thaliana (Mouse-ear cress) Length = 283 Score = 109 bits (261), Expect = 1e-22 Identities = 51/90 (56%), Positives = 61/90 (67%) Frame = +3 Query: 177 FPXFGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIKEGVVTRED 356 FP GLGTW++ PG V AV A+ IGYRHIDCA +YGNEKE+G + ++ VV RED Sbjct: 16 FPSVGLGTWQASPGLVGDAVAAAVKIGYRHIDCAQIYGNEKEIGAVLKKLFEDRVVKRED 75 Query: 357 LFITSKLWNTFHRPDLVRGALQETLEQSEL 446 LFITSKLW T H P V AL TL+ +L Sbjct: 76 LFITSKLWCTDHDPQDVPEALNRTLKDLQL 105 Score = 95.1 bits (226), Expect = 2e-18 Identities = 50/111 (45%), Positives = 66/111 (59%) Frame = +1 Query: 424 RPWNNLNFQYLDLYLIHWPQAYKEDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLV 603 R +L +Y+DLYLIHWP K+ GS+ ++ VD TWKAME L G Sbjct: 98 RTLKDLQLEYVDLYLIHWPARIKK-GSVGIKPEN----LLPVDIPSTWKAMEALYDSGKA 152 Query: 604 KSIGVSNFNSKQLERLLXHAXVKPVVNXVECHPYLNXKRLKEFCXXRGVXI 756 ++IGVSNF++K+L LL A V P VN VECHP +L+EFC +GV + Sbjct: 153 RAIGVSNFSTKKLADLLELARVPPAVNQVECHPSWRQTKLQEFCKSKGVHL 203 >UniRef50_Q0PGJ6 Cluster: Aldo-keto reductase; n=32; Magnoliophyta|Rep: Aldo-keto reductase - Arabidopsis thaliana (Mouse-ear cress) Length = 315 Score = 109 bits (261), Expect = 1e-22 Identities = 51/90 (56%), Positives = 61/90 (67%) Frame = +3 Query: 177 FPXFGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIKEGVVTRED 356 FP GLGTW++ PG V AV A+ IGYRHIDCA +YGNEKE+G + ++ VV RED Sbjct: 16 FPSVGLGTWQASPGLVGDAVAAAVKIGYRHIDCAQIYGNEKEIGAVLKKLFEDRVVKRED 75 Query: 357 LFITSKLWNTFHRPDLVRGALQETLEQSEL 446 LFITSKLW T H P V AL TL+ +L Sbjct: 76 LFITSKLWCTDHDPQDVPEALNRTLKDLQL 105 Score = 101 bits (242), Expect = 2e-20 Identities = 53/116 (45%), Positives = 69/116 (59%) Frame = +1 Query: 424 RPWNNLNFQYLDLYLIHWPQAYKEDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLV 603 R +L +Y+DLYLIHWP K+ GS+ ++ VD TWKAME L G Sbjct: 98 RTLKDLQLEYVDLYLIHWPARIKK-GSVGIKPEN----LLPVDIPSTWKAMEALYDSGKA 152 Query: 604 KSIGVSNFNSKQLERLLXHAXVKPVVNXVECHPYLNXKRLKEFCXXRGVXIXXYSP 771 ++IGVSNF++K+L LL A V P VN VECHP +L+EFC +GV + YSP Sbjct: 153 RAIGVSNFSTKKLADLLELARVPPAVNQVECHPSWRQTKLQEFCKSKGVHLSAYSP 208 >UniRef50_UPI0000E45E29 Cluster: PREDICTED: similar to aldose reductase; n=1; Strongylocentrotus purpuratus|Rep: PREDICTED: similar to aldose reductase - Strongylocentrotus purpuratus Length = 274 Score = 108 bits (260), Expect = 2e-22 Identities = 51/83 (61%), Positives = 57/83 (68%) Frame = +3 Query: 201 WKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIKEGVVTREDLFITSKLW 380 W SKPG+V AVK AID GYRHIDCA+VYGNE EVG + K VV RED+FITSKLW Sbjct: 5 WMSKPGQVEAAVKAAIDCGYRHIDCAHVYGNEAEVGAGLKEKFDANVVKREDIFITSKLW 64 Query: 381 NTFHRPDLVRGALQETLEQSELS 449 N H PD V A TL+ +LS Sbjct: 65 NNKHHPDDVEQACDITLKNLQLS 87 Score = 68.9 bits (161), Expect = 2e-10 Identities = 41/118 (34%), Positives = 57/118 (48%) Frame = +1 Query: 418 CRRPWNNLNFQYLDLYLIHWPQAYKEDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEG 597 C NL Y+DLYL+HWP AY +AME LV G Sbjct: 77 CDITLKNLQLSYVDLYLMHWPMAY--------------------------QAMEKLVTSG 110 Query: 598 LVKSIGVSNFNSKQLERLLXHAXVKPVVNXVECHPYLNXKRLKEFCXXRGVXIXXYSP 771 K+IG+SNF+ K ++R++ A ++P VE HP L ++L EFC + + YSP Sbjct: 111 KCKAIGLSNFSMKMMKRVIEKATIQPANLQVELHPLLTQEKLIEFCKEHNMTVTAYSP 168 >UniRef50_A2R6Z3 Cluster: Catalytic activity: an alcohol + NADP(+) <=> an aldehyde + NADPH; n=9; Pezizomycotina|Rep: Catalytic activity: an alcohol + NADP(+) <=> an aldehyde + NADPH - Aspergillus niger Length = 345 Score = 107 bits (258), Expect = 3e-22 Identities = 51/114 (44%), Positives = 71/114 (62%), Gaps = 2/114 (1%) Frame = +1 Query: 436 NLNFQYLDLYLIHWPQAYKEDGSLFP--TDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKS 609 +L YLDLYLIHWP A++ + +Q+G I DV DTW AME LV++G V+S Sbjct: 97 DLQTDYLDLYLIHWPVAFRYSTTTIQPVNEQTGLIDVVDVPIKDTWAAMEKLVEKGKVRS 156 Query: 610 IGVSNFNSKQLERLLXHAXVKPVVNXVECHPYLNXKRLKEFCXXRGVXIXXYSP 771 IGVSNF +++E LL A + P VN +E HP+L + L E+ +G+ + YSP Sbjct: 157 IGVSNFTREKIEELLKTAKITPAVNQIEAHPFLQQRDLLEWSTQKGIVVAGYSP 210 Score = 91.1 bits (216), Expect = 3e-17 Identities = 45/92 (48%), Positives = 59/92 (64%) Frame = +3 Query: 180 PXFGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIKEGVVTREDL 359 P GLGTW+SK EV AV A+ GYRHID A VYGNE+EVG+ ++ V RE++ Sbjct: 16 PAVGLGTWQSKKDEVRDAVIAALKCGYRHIDAAAVYGNEQEVGDG----MRLSGVPREEI 71 Query: 360 FITSKLWNTFHRPDLVRGALQETLEQSELSVL 455 F+TSKLWNT H P+ V A+ ++L + L Sbjct: 72 FLTSKLWNTHHHPENVEEAVDKSLADLQTDYL 103 >UniRef50_Q8VC28 Cluster: Aldo-keto reductase family 1 member C13; n=11; Theria|Rep: Aldo-keto reductase family 1 member C13 - Mus musculus (Mouse) Length = 323 Score = 107 bits (258), Expect = 3e-22 Identities = 49/111 (44%), Positives = 69/111 (62%), Gaps = 2/111 (1%) Frame = +1 Query: 439 LNFQYLDLYLIHWPQAYKEDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGV 618 L Y+DLY++H+P K + FP ++ GK VD+ DTW+ +E GLVKSIGV Sbjct: 106 LQLDYVDLYIMHYPVPMKSGDNDFPVNEQGKSLLDTVDFCDTWERLEECKDAGLVKSIGV 165 Query: 619 SNFNSKQLERLLXHAXV--KPVVNXVECHPYLNXKRLKEFCXXRGVXIXXY 765 SNFN +QLER+L + KPV N VECH YLN ++L ++C + + + Y Sbjct: 166 SNFNHRQLERILNKPGLKYKPVCNQVECHLYLNQRKLLDYCESKDIVLVAY 216 Score = 100 bits (239), Expect = 6e-20 Identities = 48/94 (51%), Positives = 69/94 (73%), Gaps = 3/94 (3%) Frame = +3 Query: 174 LFPXFGLGTWKSKPGEVTQAVKDA---IDIGYRHIDCAYVYGNEKEVGEAITSKIKEGVV 344 L P G GT+K K +++++ A +D+GYRH+D AY Y E+E+G+AI SKIK GVV Sbjct: 15 LIPALGFGTYKPKEVPKSKSLEAACLALDVGYRHVDTAYAYQVEEEIGQAIQSKIKAGVV 74 Query: 345 TREDLFITSKLWNTFHRPDLVRGALQETLEQSEL 446 REDLFIT+KLW T RP+LV+ AL+++L++ +L Sbjct: 75 KREDLFITTKLWCTCFRPELVKPALEKSLKKLQL 108 >UniRef50_Q22352 Cluster: Putative uncharacterized protein T08H10.1; n=2; Caenorhabditis|Rep: Putative uncharacterized protein T08H10.1 - Caenorhabditis elegans Length = 333 Score = 105 bits (252), Expect = 2e-21 Identities = 47/112 (41%), Positives = 72/112 (64%), Gaps = 1/112 (0%) Frame = +1 Query: 439 LNFQYLDLYLIHWPQAYK-EDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIG 615 L +Y+DLYLIH P +K ++GS P ++G++ +++ ++DTW+A+E L KEG +K++G Sbjct: 102 LQLEYIDLYLIHCPFPFKHQEGSFAPLMENGELAVTEIAHIDTWRALEKLYKEGKLKALG 161 Query: 616 VSNFNSKQLERLLXHAXVKPVVNXVECHPYLNXKRLKEFCXXRGVXIXXYSP 771 VSNF+ QL+ L A VKP VECH Y + L+ C GV + Y+P Sbjct: 162 VSNFSCNQLQALYDAAEVKPANQQVECHIYWPQQELRALCKKLGVTVTAYAP 213 Score = 78.2 bits (184), Expect = 3e-13 Identities = 39/93 (41%), Positives = 58/93 (62%), Gaps = 1/93 (1%) Frame = +3 Query: 180 PXFGLGTWKSKP-GEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIKEGVVTRED 356 P FGLGTW+ K E+T A++ A+D GYR ID A++Y NE +G+ + I G + RED Sbjct: 15 PLFGLGTWQVKDEAELTVALRAALDAGYRLIDTAHLYQNEHIIGKVLHEYISSGKLKRED 74 Query: 357 LFITSKLWNTFHRPDLVRGALQETLEQSELSVL 455 +F+TSKL T H P+ V ++ L+ +L + Sbjct: 75 IFVTSKLPFTAHAPEDVPKCVESQLKALQLEYI 107 >UniRef50_UPI0000499B0E Cluster: oxidoreductase, aldo/keto reductase family; n=1; Entamoeba histolytica HM-1:IMSS|Rep: oxidoreductase, aldo/keto reductase family - Entamoeba histolytica HM-1:IMSS Length = 307 Score = 105 bits (251), Expect = 2e-21 Identities = 51/118 (43%), Positives = 69/118 (58%) Frame = +1 Query: 418 CRRPWNNLNFQYLDLYLIHWPQAYKEDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEG 597 C +L +YLDLYLIHWP A K D S P + F D+D + W+ ME LV EG Sbjct: 91 CLESIQDLKCKYLDLYLIHWPIALKVDASNPPKPED----FLDMDITEIWQEMERLVDEG 146 Query: 598 LVKSIGVSNFNSKQLERLLXHAXVKPVVNXVECHPYLNXKRLKEFCXXRGVXIXXYSP 771 LVKSIG+SNF Q+E+++ +KPV+N VE + YL +L+E C + + Y P Sbjct: 147 LVKSIGLSNFTIPQIEKIMKMCRIKPVINQVELNVYLQQNKLREVCKSYNIVVEAYRP 204 Score = 73.7 bits (173), Expect = 6e-12 Identities = 38/68 (55%), Positives = 46/68 (67%), Gaps = 1/68 (1%) Frame = +3 Query: 180 PXFGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGE-AITSKIKEGVVTRED 356 P GLGTW + PGEV +AV A++ GYR IDCA Y NEKE+GE I +K RE+ Sbjct: 15 PAIGLGTWLAAPGEVGKAVTLALENGYRLIDCARFYKNEKEIGEMGIEPFLKNH--PREE 72 Query: 357 LFITSKLW 380 LF+TSKLW Sbjct: 73 LFVTSKLW 80 >UniRef50_A4RQH8 Cluster: Predicted protein; n=2; Ostreococcus|Rep: Predicted protein - Ostreococcus lucimarinus CCE9901 Length = 337 Score = 105 bits (251), Expect = 2e-21 Identities = 47/84 (55%), Positives = 56/84 (66%) Frame = +3 Query: 180 PXFGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIKEGVVTREDL 359 P GLGTWK++P EV AV+DA+ GY H+DCA Y NE EVGEA+ + G RED+ Sbjct: 17 PRVGLGTWKARPNEVRDAVRDALGAGYAHVDCAAAYANESEVGEALREAFERGDAKREDV 76 Query: 360 FITSKLWNTFHRPDLVRGALQETL 431 F+TSKLWN RP VR AL TL Sbjct: 77 FVTSKLWNDRRRPRDVREALMTTL 100 Score = 79.4 bits (187), Expect = 1e-13 Identities = 43/115 (37%), Positives = 60/115 (52%), Gaps = 2/115 (1%) Frame = +1 Query: 433 NNLNFQYLDLYLIHWPQAYKEDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSI 612 N+L YLDLYLIHWP A+K G++ D I + W +E V +GLV+ I Sbjct: 101 NDLGVGYLDLYLIHWPVAWKR-GTVLQPDAEASI-------AECWSELERCVADGLVRHI 152 Query: 613 GVSNFNSKQLERLL--XHAXVKPVVNXVECHPYLNXKRLKEFCXXRGVXIXXYSP 771 GVSNFN QL L ++P N +E HP + L ++ +G+ + YSP Sbjct: 153 GVSNFNEAQLAALCDDPRTKIQPACNQIESHPLWSNDSLVKYSQSKGLTVTAYSP 207 >UniRef50_P51857 Cluster: 3-oxo-5-beta-steroid 4-dehydrogenase (EC 1.3.1.3) (Delta(4)-3- ketosteroid 5-beta-reductase); n=124; cellular organisms|Rep: 3-oxo-5-beta-steroid 4-dehydrogenase (EC 1.3.1.3) (Delta(4)-3- ketosteroid 5-beta-reductase) - Homo sapiens (Human) Length = 326 Score = 105 bits (251), Expect = 2e-21 Identities = 50/113 (44%), Positives = 67/113 (59%), Gaps = 2/113 (1%) Frame = +1 Query: 439 LNFQYLDLYLIHWPQAYKEDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGV 618 L Y+DLY+I P A+K ++P D++GK + + TW+AME GLVKS+GV Sbjct: 109 LQLDYVDLYIIEVPMAFKPGDEIYPRDENGKWLYHKSNLCATWEAMEACKDAGLVKSLGV 168 Query: 619 SNFNSKQLERLLXHAXV--KPVVNXVECHPYLNXKRLKEFCXXRGVXIXXYSP 771 SNFN +QLE +L + KPV N VECHPY +L +FC + I YSP Sbjct: 169 SNFNRRQLELILNKPGLKHKPVSNQVECHPYFTQPKLLKFCQQHDIVITAYSP 221 Score = 98.3 bits (234), Expect = 2e-19 Identities = 56/110 (50%), Positives = 65/110 (59%), Gaps = 8/110 (7%) Frame = +3 Query: 180 PXFGLGTW---KSKP-GEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIKEGVVT 347 P GLGT+ KS P G +VK AID GYRHID AY+Y NE EVGEAI KI EG V Sbjct: 19 PIIGLGTYSEPKSTPKGACATSVKVAIDTGYRHIDGAYIYQNEHEVGEAIREKIAEGKVR 78 Query: 348 REDLFITSKLWNTFHRPDLVRGALQETLEQSELSVLG----SVPDTLAPG 485 RED+F KLW T H P++VR L+ TL +L + VP PG Sbjct: 79 REDIFYCGKLWATNHVPEMVRPTLERTLRVLQLDYVDLYIIEVPMAFKPG 128 >UniRef50_UPI0000498F1F Cluster: oxidoreductase, aldo/keto reductase family; n=2; Entamoeba histolytica HM-1:IMSS|Rep: oxidoreductase, aldo/keto reductase family - Entamoeba histolytica HM-1:IMSS Length = 305 Score = 104 bits (250), Expect = 3e-21 Identities = 51/92 (55%), Positives = 64/92 (69%) Frame = +3 Query: 180 PXFGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIKEGVVTREDL 359 P GLGTW S GEV +AV+ AI GYRHIDCA YGNEKEVG+ I S I +G V RE+L Sbjct: 14 PKLGLGTWMSANGEVGKAVEIAIKNGYRHIDCAKAYGNEKEVGDGIKSAIAKGYVKREEL 73 Query: 360 FITSKLWNTFHRPDLVRGALQETLEQSELSVL 455 F+T+KLW+T + VR A E+L++ +L L Sbjct: 74 FVTTKLWSTDKHKEDVRPACLESLKKLQLEYL 105 Score = 92.7 bits (220), Expect = 1e-17 Identities = 49/118 (41%), Positives = 64/118 (54%) Frame = +1 Query: 418 CRRPWNNLNFQYLDLYLIHWPQAYKEDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEG 597 C L +YLDLY+IH P L ++G+ + +TW+ ME LV+EG Sbjct: 93 CLESLKKLQLEYLDLYIIHIP--------LTADKKTGEFTEEIIPIEETWREMEKLVEEG 144 Query: 598 LVKSIGVSNFNSKQLERLLXHAXVKPVVNXVECHPYLNXKRLKEFCXXRGVXIXXYSP 771 LVKSIGVSNFN K+LE LL A ++P VN E H Y +L +FC + I Y P Sbjct: 145 LVKSIGVSNFNIKKLEELLAIAKIQPAVNQFEFHIYYQRPKLHQFCKKHNIHITGYCP 202 >UniRef50_A3U9Y0 Cluster: Aldehyde reductase; n=5; Bacteroidetes|Rep: Aldehyde reductase - Croceibacter atlanticus HTCC2559 Length = 316 Score = 103 bits (247), Expect = 6e-21 Identities = 48/92 (52%), Positives = 61/92 (66%) Frame = +3 Query: 180 PXFGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIKEGVVTREDL 359 P GLGTWKS P +V +AVK A++ GY+HIDCA Y NE VGEA + G V RED+ Sbjct: 13 PSIGLGTWKSDPEDVKKAVKIALENGYKHIDCAAAYDNEDAVGEAFKESFESGNVKREDI 72 Query: 360 FITSKLWNTFHRPDLVRGALQETLEQSELSVL 455 F+TSKLWN H+ + V AL++TL+ L L Sbjct: 73 FVTSKLWNNAHKKEDVIPALKKTLKDLNLDYL 104 Score = 95.1 bits (226), Expect = 2e-18 Identities = 44/117 (37%), Positives = 63/117 (53%) Frame = +1 Query: 421 RRPWNNLNFQYLDLYLIHWPQAYKEDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGL 600 ++ +LN YLDLYL+HWP A+K + FP + + +T AM K+GL Sbjct: 93 KKTLKDLNLDYLDLYLMHWPVAFKPSVNGFPEKDEDYLSLEEAPLHETLNAMIEAKKQGL 152 Query: 601 VKSIGVSNFNSKQLERLLXHAXVKPVVNXVECHPYLNXKRLKEFCXXRGVXIXXYSP 771 +K +GVSNF+ ++LE L P +N VE HPYL L +C G+ + YSP Sbjct: 153 IKHVGVSNFSKEKLESLKGKVEEMPEMNQVELHPYLPQNDLYSYCSKEGILLTGYSP 209 >UniRef50_P27800 Cluster: Aldehyde reductase 1; n=18; root|Rep: Aldehyde reductase 1 - Sporobolomyces salmonicolor Length = 323 Score = 103 bits (246), Expect = 8e-21 Identities = 52/89 (58%), Positives = 61/89 (68%) Frame = +3 Query: 189 GLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIKEGVVTREDLFIT 368 G GTW++ PGEV Q VK AI+ GYRH+D A VY N+ EVG A IKE V REDLFIT Sbjct: 17 GYGTWQAAPGEVGQGVKVAIETGYRHLDLAKVYSNQPEVGAA----IKEAGVKREDLFIT 72 Query: 369 SKLWNTFHRPDLVRGALQETLEQSELSVL 455 SKLWN HRP+ V AL +TL++ L L Sbjct: 73 SKLWNNSHRPEQVEPALDDTLKELGLEYL 101 Score = 92.7 bits (220), Expect = 1e-17 Identities = 48/116 (41%), Positives = 67/116 (57%), Gaps = 5/116 (4%) Frame = +1 Query: 439 LNFQYLDLYLIHWPQAYKEDG----SLFPTDQSGKIQFS-DVDYVDTWKAMEPLVKEGLV 603 L +YLDLYLIHWP A+ +G +LFP +++ +V VDTWKAM L+ G V Sbjct: 96 LGLEYLDLYLIHWPVAFPPEGDITQNLFPKANDKEVKLDLEVSLVDTWKAMVKLLDTGKV 155 Query: 604 KSIGVSNFNSKQLERLLXHAXVKPVVNXVECHPYLNXKRLKEFCXXRGVXIXXYSP 771 K+IGVSNF++K ++ ++ V P VN +E HP L L + + I YSP Sbjct: 156 KAIGVSNFDAKMVDAIIEATGVTPSVNQIERHPLLLQPELIAHHKAKNIHITAYSP 211 >UniRef50_Q10494 Cluster: Probable oxidoreductase C26F1.07; n=2; Schizosaccharomyces pombe|Rep: Probable oxidoreductase C26F1.07 - Schizosaccharomyces pombe (Fission yeast) Length = 321 Score = 102 bits (245), Expect = 1e-20 Identities = 53/134 (39%), Positives = 73/134 (54%), Gaps = 8/134 (5%) Frame = +1 Query: 394 ARTWC------AVP--CRRPWNNLNFQYLDLYLIHWPQAYKEDGSLFPTDQSGKIQFSDV 549 ++ WC AVP + +L YLD YLIHWP ++K FP D+ G + + Sbjct: 84 SKLWCNAHAPEAVPKALEKTLKDLKLDYLDEYLIHWPVSFKTGEDKFPKDKDGNLIYEKN 143 Query: 550 DYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLXHAXVKPVVNXVECHPYLNXKRLKE 729 +TWKAME L++ G V+ IG+SNFN LER+L A VKP V+ +E HP+L E Sbjct: 144 PIEETWKAMEKLLETGKVRHIGLSNFNDTNLERILKVAKVKPAVHQMELHPFLPQTEFVE 203 Query: 730 FCXXRGVXIXXYSP 771 G+ + YSP Sbjct: 204 KHKKLGIHVTAYSP 217 Score = 97.5 bits (232), Expect = 4e-19 Identities = 46/92 (50%), Positives = 61/92 (66%) Frame = +3 Query: 180 PXFGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIKEGVVTREDL 359 P GLGTW+S+P + AVK A+ GYRHID A +YGNE EVG+ IKE V R+D+ Sbjct: 25 PGLGLGTWRSEPNQTKNAVKTALQYGYRHIDAAAIYGNEDEVGDG----IKESGVPRKDI 80 Query: 360 FITSKLWNTFHRPDLVRGALQETLEQSELSVL 455 ++TSKLW H P+ V AL++TL+ +L L Sbjct: 81 WVTSKLWCNAHAPEAVPKALEKTLKDLKLDYL 112 >UniRef50_A2EYY6 Cluster: Oxidoreductase, aldo/keto reductase family protein; n=9; Trichomonas vaginalis G3|Rep: Oxidoreductase, aldo/keto reductase family protein - Trichomonas vaginalis G3 Length = 308 Score = 102 bits (244), Expect = 1e-20 Identities = 55/122 (45%), Positives = 72/122 (59%), Gaps = 5/122 (4%) Frame = +1 Query: 418 CRRPWNNLNFQYLDLYLIHWPQAYKEDG---SLFPTDQSGKIQFSD-VDYVDTWKAMEPL 585 CR+ +L YLDLYL+H+P A++ G SL P D+ G F D V +DTWKAME L Sbjct: 85 CRKTLKDLRLDYLDLYLMHYPFAFQNTGIGGSLNPLDEKGNTIFDDGVSLIDTWKAMEKL 144 Query: 586 VKEGLVKSIGVSNFNSKQLERL-LXHAXVKPVVNXVECHPYLNXKRLKEFCXXRGVXIXX 762 V++GLVK IGVSN+ QLERL A P N VE + Y+ L+E+ G+ + Sbjct: 145 VEKGLVKRIGVSNWTINQLERLKYSDAKTTPYTNQVEFNLYMQQGPLREYMHKEGIIVTG 204 Query: 763 YS 768 YS Sbjct: 205 YS 206 Score = 81.0 bits (191), Expect = 4e-14 Identities = 45/97 (46%), Positives = 59/97 (60%), Gaps = 5/97 (5%) Frame = +3 Query: 180 PXFGLGTWKSKPGE-----VTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIKEGVV 344 P GLGTWKS E +T A+K+A GY HIDCA Y NE VG+A+ G+ Sbjct: 5 PTIGLGTWKSPRSEDLVNAITYAIKEA---GYVHIDCALCYENEDIVGQALQQCWDSGI- 60 Query: 345 TREDLFITSKLWNTFHRPDLVRGALQETLEQSELSVL 455 RE+++ITSKLWNT HR ++V A ++TL+ L L Sbjct: 61 KRENIWITSKLWNTHHRLEIVEEACRKTLKDLRLDYL 97 >UniRef50_UPI00015B4B22 Cluster: PREDICTED: similar to GA15457-PA; n=1; Nasonia vitripennis|Rep: PREDICTED: similar to GA15457-PA - Nasonia vitripennis Length = 388 Score = 101 bits (243), Expect = 2e-20 Identities = 51/118 (43%), Positives = 69/118 (58%), Gaps = 1/118 (0%) Frame = +1 Query: 421 RRPWNNLNFQYLDLYLIHWPQAYKEDGSLFPT-DQSGKIQFSDVDYVDTWKAMEPLVKEG 597 +R +L Y+D+YLIH P A KE +L D+ G F DVD+ WKAME VKEG Sbjct: 114 KRSLKDLGLDYVDMYLIHTPFAVKEGENLSSKQDKDGNDLFDDVDHKALWKAMERQVKEG 173 Query: 598 LVKSIGVSNFNSKQLERLLXHAXVKPVVNXVECHPYLNXKRLKEFCXXRGVXIXXYSP 771 KSIG+SNFN Q+ + +A +KP VE H YL K+L++FC + + Y+P Sbjct: 174 RAKSIGLSNFNQSQVLNIYNNAEIKPSNLQVETHAYLQQKQLRKFCKEHNIVMTAYAP 231 Score = 65.3 bits (152), Expect = 2e-09 Identities = 35/85 (41%), Positives = 50/85 (58%) Frame = +3 Query: 180 PXFGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIKEGVVTREDL 359 P GLGT K E+ A+ A++ GYRHID A+ Y NE +G+ + +G RED+ Sbjct: 35 PAVGLGTSTIKLDEMDNAISSALENGYRHIDTAFSYDNEAAIGKILKKWFDKG-GKREDI 93 Query: 360 FITSKLWNTFHRPDLVRGALQETLE 434 FITSKL + +RP V L+ +L+ Sbjct: 94 FITSKLPSQGNRPQSVETYLKRSLK 118 >UniRef50_Q7PLK6 Cluster: CG40064-PA; n=1; Drosophila melanogaster|Rep: CG40064-PA - Drosophila melanogaster (Fruit fly) Length = 361 Score = 101 bits (243), Expect = 2e-20 Identities = 50/112 (44%), Positives = 71/112 (63%), Gaps = 2/112 (1%) Frame = +1 Query: 418 CRRPWNNLNFQYLDLYLIHWPQAYKE--DGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVK 591 C + L F Y+DLYL+H+P YK D L P ++Q ++DY+DTW+AME LVK Sbjct: 111 CEKQLELLGFSYIDLYLMHFPVGYKYVCDEILMPMS-GDELQTVEIDYLDTWRAMENLVK 169 Query: 592 EGLVKSIGVSNFNSKQLERLLXHAXVKPVVNXVECHPYLNXKRLKEFCXXRG 747 G+V+SIG+SNFN +Q++R++ + KPVVN VE P K L ++C G Sbjct: 170 LGMVRSIGLSNFNMEQIQRIIQCSSSKPVVNQVEIWPGFLQKDLVDYCRYNG 221 Score = 81.4 bits (192), Expect = 3e-14 Identities = 36/72 (50%), Positives = 52/72 (72%) Frame = +3 Query: 219 EVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIKEGVVTREDLFITSKLWNTFHRP 398 + + AV AI+ G+RH D AY Y NEKE+GEA+ ++IK G ++RE++F+T+KLWNT H P Sbjct: 45 QCSAAVHCAIETGFRHFDTAYYYENEKEIGEALRTQIKMGNISRENIFLTTKLWNTHHDP 104 Query: 399 DLVRGALQETLE 434 VR ++ LE Sbjct: 105 RDVRRICEKQLE 116 >UniRef50_A2EHN6 Cluster: Oxidoreductase, aldo/keto reductase family protein; n=10; Trichomonas vaginalis|Rep: Oxidoreductase, aldo/keto reductase family protein - Trichomonas vaginalis G3 Length = 312 Score = 101 bits (242), Expect = 2e-20 Identities = 46/114 (40%), Positives = 71/114 (62%), Gaps = 4/114 (3%) Frame = +1 Query: 439 LNFQYLDLYLIHWPQAYK----EDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVK 606 L Y+DL+LIH P A+K +DG++ P D+ GKIQ+ +D ++T+ AME K+GL + Sbjct: 92 LQLSYVDLFLIHQPIAFKSLPAKDGTMMPKDEKGKIQYEQIDILETYHAMEECQKKGLTR 151 Query: 607 SIGVSNFNSKQLERLLXHAXVKPVVNXVECHPYLNXKRLKEFCXXRGVXIXXYS 768 IGVSNF+ +QLER+ + +KP N VEC+ Y K L +C + + ++ Sbjct: 152 HIGVSNFSIEQLERIWFNCEIKPYANQVECNIYRQFKPLLSYCESHNIYLMAHT 205 Score = 78.2 bits (184), Expect = 3e-13 Identities = 40/92 (43%), Positives = 55/92 (59%), Gaps = 2/92 (2%) Frame = +3 Query: 180 PXFGLGTWKSK-PGEVTQAVKDAID-IGYRHIDCAYVYGNEKEVGEAITSKIKEGVVTRE 353 P G GT+ + P ++ A+ AI+ G RHID A+ Y N+ +GE + +G + RE Sbjct: 4 PQLGFGTYLANDPAKLKAALHYAIEECGVRHIDTAFAYYNQNVIGETLKEIFAKGKIKRE 63 Query: 354 DLFITSKLWNTFHRPDLVRGALQETLEQSELS 449 D+FIT+KLW T HR DLV L E L Q +LS Sbjct: 64 DMFITTKLWCTHHRKDLVEPELHENLAQLQLS 95 >UniRef50_Q01J82 Cluster: OSIGBa0152K17.5 protein; n=28; Magnoliophyta|Rep: OSIGBa0152K17.5 protein - Oryza sativa (Rice) Length = 323 Score = 101 bits (241), Expect = 3e-20 Identities = 45/117 (38%), Positives = 68/117 (58%) Frame = +1 Query: 421 RRPWNNLNFQYLDLYLIHWPQAYKEDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGL 600 R NL +Y+DLYL+HWP + K + P + + F D+ W+AME + GL Sbjct: 102 RESLRNLQMEYVDLYLVHWPISVKPGPPMLPVKREDAVPF---DFEGVWRAMEECHRLGL 158 Query: 601 VKSIGVSNFNSKQLERLLXHAXVKPVVNXVECHPYLNXKRLKEFCXXRGVXIXXYSP 771 K+IGVSNF +K L++LL A + P VN VE +P + ++E+C +G+ + YSP Sbjct: 159 AKAIGVSNFTTKHLDKLLAVATIPPAVNQVEMNPVWQQRTVREYCAAKGIRVAAYSP 215 Score = 67.3 bits (157), Expect = 5e-10 Identities = 36/93 (38%), Positives = 55/93 (59%), Gaps = 4/93 (4%) Frame = +3 Query: 180 PXFGLGTWKS---KPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIKEGVV-T 347 P G+GT S P A A+++G+RH D A +YG E +GEAI + G+V + Sbjct: 18 PAVGVGTADSAATSPETKRGAALAALEVGFRHFDTAALYGTEAPLGEAIAEATRRGLVAS 77 Query: 348 REDLFITSKLWNTFHRPDLVRGALQETLEQSEL 446 RE++F+T+KLW T P LV +L+E+L ++ Sbjct: 78 REEVFVTTKLWCTQCHPGLVLPSLRESLRNLQM 110 >UniRef50_Q9U2J5 Cluster: Putative uncharacterized protein; n=2; Caenorhabditis|Rep: Putative uncharacterized protein - Caenorhabditis elegans Length = 339 Score = 100 bits (240), Expect = 4e-20 Identities = 42/110 (38%), Positives = 73/110 (66%), Gaps = 5/110 (4%) Frame = +1 Query: 451 YLDLYLIHWPQAYKEDG-----SLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIG 615 Y+DL +IHWP + ED L+P +GK+++SDVDY++TWKA+E + G ++SIG Sbjct: 106 YMDLIVIHWPFGWAEDEPPGERGLWPRGANGKMRYSDVDYLETWKALEDAHRSGKIRSIG 165 Query: 616 VSNFNSKQLERLLXHAXVKPVVNXVECHPYLNXKRLKEFCXXRGVXIXXY 765 ++NFN Q+E++ +KP V VE +P+L+ + +++FC +G+ + + Sbjct: 166 LANFNIGQVEQVWTKGLIKPAVLQVEMNPFLDQEEIRQFCREKGIILTAF 215 Score = 75.4 bits (177), Expect = 2e-12 Identities = 35/92 (38%), Positives = 52/92 (56%) Frame = +3 Query: 180 PXFGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIKEGVVTREDL 359 P G GTW+ + V+DA++ GYRHID A + N++EV I K V RE+L Sbjct: 16 PVIGYGTWQLPKNLAAERVRDALEAGYRHIDSALSFKNQEEVAAGIKDWCKIRKVRREEL 75 Query: 360 FITSKLWNTFHRPDLVRGALQETLEQSELSVL 455 F++SK+WNT+H + + E LE E + + Sbjct: 76 FLSSKIWNTYHSRNRCMQQIDEMLEIFETTYM 107 >UniRef50_Q16K66 Cluster: Aldo-keto reductase; n=2; Aedes aegypti|Rep: Aldo-keto reductase - Aedes aegypti (Yellowfever mosquito) Length = 303 Score = 100 bits (239), Expect = 6e-20 Identities = 49/119 (41%), Positives = 72/119 (60%), Gaps = 1/119 (0%) Frame = +1 Query: 418 CRRPWNNLNFQYLDLYLIHWPQAYKEDGSLFPTDQSGKIQFSD-VDYVDTWKAMEPLVKE 594 CR L Y+DLYL+H P A ++ G D + + + D V ++TWKA+E ++ Sbjct: 91 CRLSLERLGLDYVDLYLMHTPVAARDSG-----DGNDRSEIDDEVTPLETWKALEECQRK 145 Query: 595 GLVKSIGVSNFNSKQLERLLXHAXVKPVVNXVECHPYLNXKRLKEFCXXRGVXIXXYSP 771 GLV+SIGVSNFN +QL ++ H ++PVVN VEC + +L++FC G+ I YSP Sbjct: 146 GLVRSIGVSNFNEEQLMEIVTHGSIRPVVNQVECSIGFHQVKLRKFCNREGILIMAYSP 204 Score = 80.2 bits (189), Expect = 6e-14 Identities = 39/87 (44%), Positives = 55/87 (63%), Gaps = 1/87 (1%) Frame = +3 Query: 180 PXFGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIKEG-VVTRED 356 P GLGT+K + A+K A++ GYR ID A+VY NE+ VG+A+ +G + RED Sbjct: 11 PPIGLGTYKITGSDGVAAIKSAVEFGYRLIDTAFVYNNEQVVGQALREIFSQGNDINRED 70 Query: 357 LFITSKLWNTFHRPDLVRGALQETLEQ 437 +FI SKL TFHRP+ V + +LE+ Sbjct: 71 VFIVSKLGPTFHRPEAVEKGCRLSLER 97 >UniRef50_Q7ZA52 Cluster: Aldose reductase; n=6; Pezizomycotina|Rep: Aldose reductase - Magnaporthe grisea (Rice blast fungus) (Pyricularia grisea) Length = 312 Score = 99 bits (238), Expect = 7e-20 Identities = 53/135 (39%), Positives = 70/135 (51%), Gaps = 3/135 (2%) Frame = +1 Query: 400 TWCAVPCRRPWNNLNFQYLDLYLIHWPQAYKEDGS--LFPTDQSGKIQFSDV-DYVDTWK 570 T C + + L Y+DLYL+HWP +G+ FP G ++VDTWK Sbjct: 86 TRCELGLDQSLKLLGLDYVDLYLVHWPILMNPEGNDEKFPKHADGSRDIIHTHNHVDTWK 145 Query: 571 AMEPLVKEGLVKSIGVSNFNSKQLERLLXHAXVKPVVNXVECHPYLNXKRLKEFCXXRGV 750 ME L G K++GVSN++ LE+LL HA P VN VE HP L + L +FC +G+ Sbjct: 146 LMEKLPATGKTKAVGVSNYSKAWLEQLLPHATTVPAVNQVENHPQLPQQELVDFCKEKGI 205 Query: 751 XIXXYSPPRXXGXXL 795 I YSP G L Sbjct: 206 HIMAYSPLGSTGGPL 220 Score = 89.4 bits (212), Expect = 1e-16 Identities = 40/70 (57%), Positives = 48/70 (68%) Frame = +3 Query: 180 PXFGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIKEGVVTREDL 359 P FGLGTW+ G + +AV AI GYR ID AYVYGNE+EVG+ I I G+V REDL Sbjct: 15 PAFGLGTWQGDKGVIKEAVLTAIKSGYRLIDGAYVYGNEEEVGQGIREAISSGIVKREDL 74 Query: 360 FITSKLWNTF 389 F+ SK W T+ Sbjct: 75 FVVSKCWATY 84 >UniRef50_UPI0000D9A956 Cluster: PREDICTED: similar to aldo-keto reductase family 1, member B10, partial; n=1; Macaca mulatta|Rep: PREDICTED: similar to aldo-keto reductase family 1, member B10, partial - Macaca mulatta Length = 275 Score = 99.1 bits (236), Expect = 1e-19 Identities = 54/90 (60%), Positives = 61/90 (67%), Gaps = 6/90 (6%) Frame = +3 Query: 204 KSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIKEGVVTREDLFITSK--- 374 KS G+V +AVK AID GYRHIDCAYVY NE EVGEAI KI+E V REDLFI SK Sbjct: 42 KSPLGKVKEAVKVAIDAGYRHIDCAYVYQNEHEVGEAIQEKIQEQAVKREDLFIVSKVHM 101 Query: 375 ---LWNTFHRPDLVRGALQETLEQSELSVL 455 LW TF LVR A ++TL+ +LS L Sbjct: 102 AHWLWTTFFERPLVRKAFEKTLKDLKLSYL 131 Score = 88.2 bits (209), Expect = 2e-16 Identities = 52/132 (39%), Positives = 68/132 (51%), Gaps = 2/132 (1%) Frame = +1 Query: 382 TRFIARTWCAVPCRRPWNNLNFQYLDLYLIHWPQAYKEDGSLFPTDQSGKIQFSDVDYVD 561 T F R + +L YLD+YLIHWPQ +K Sbjct: 107 TTFFERPLVRKAFEKTLKDLKLSYLDVYLIHWPQGFK----------------------- 143 Query: 562 TWKAMEPLVKEGLVKSIGVSNFNSKQLERLLXHAXV--KPVVNXVECHPYLNXKRLKEFC 735 AME LV EGLVK++G+SNFN Q+E+LL + KPV N VECHPYL ++L ++C Sbjct: 144 ---AMEELVDEGLVKALGISNFNHFQIEKLLNKPGLKYKPVTNQVECHPYLTQEKLIQYC 200 Query: 736 XXRGVXIXXYSP 771 +G+ I YSP Sbjct: 201 HSKGITITAYSP 212 >UniRef50_Q6TY50 Cluster: Reductase 2; n=10; Magnoliophyta|Rep: Reductase 2 - Hydrangea macrophylla (Bigleaf hydrangea) Length = 321 Score = 99.1 bits (236), Expect = 1e-19 Identities = 48/111 (43%), Positives = 65/111 (58%) Frame = +1 Query: 436 NLNFQYLDLYLIHWPQAYKEDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIG 615 NL +Y+D+YLIHWP + K +P K F +DY W+AME K GL K+IG Sbjct: 107 NLKLEYIDMYLIHWPVSSKPGNYEYPIK---KEDFLQMDYKSVWEAMEECQKLGLTKAIG 163 Query: 616 VSNFNSKQLERLLXHAXVKPVVNXVECHPYLNXKRLKEFCXXRGVXIXXYS 768 VSNF+ K+L +L +A V P VN VE +P K+L EFC G+ + Y+ Sbjct: 164 VSNFSCKKLSDVLANAKVPPAVNQVEVNPCWQQKQLTEFCKSNGILVVAYA 214 Score = 73.7 bits (173), Expect = 6e-12 Identities = 39/96 (40%), Positives = 61/96 (63%), Gaps = 4/96 (4%) Frame = +3 Query: 180 PXFGLGTWKSKPGE---VTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIKEGVV-T 347 P GLGT P + V +AV +A+ +GYRH D A +Y +E+ +G+AI + EG++ + Sbjct: 18 PVLGLGTAADPPVDPETVRKAVTEALKLGYRHFDTAALYNSEQPLGDAIAEALGEGLIKS 77 Query: 348 REDLFITSKLWNTFHRPDLVRGALQETLEQSELSVL 455 R++LFITSKLW + + V ALQ+TL+ +L + Sbjct: 78 RDELFITSKLWCSDAHRENVEPALQKTLKNLKLEYI 113 >UniRef50_A2QL02 Cluster: Putative frameshift; n=1; Aspergillus niger|Rep: Putative frameshift - Aspergillus niger Length = 357 Score = 99.1 bits (236), Expect = 1e-19 Identities = 42/107 (39%), Positives = 65/107 (60%) Frame = +1 Query: 451 YLDLYLIHWPQAYKEDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFN 630 Y+DL L+H+P +K FP D G++ + +VDTW+A+E +VK G V++IGVSNF+ Sbjct: 132 YVDLLLMHYPCTFKRGEDRFPRDAEGRMIHGETTFVDTWRALEKVVKTGKVRAIGVSNFS 191 Query: 631 SKQLERLLXHAXVKPVVNXVECHPYLNXKRLKEFCXXRGVXIXXYSP 771 ++E LL P V+ +E HPYL K E+ +G+ + +SP Sbjct: 192 KGEIETLLRETSTVPAVHQMEVHPYLQQKGFNEWLREKGIHVVQFSP 238 Score = 54.0 bits (124), Expect = 5e-06 Identities = 34/85 (40%), Positives = 49/85 (57%), Gaps = 1/85 (1%) Frame = +3 Query: 180 PXFGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIKEGVVTREDL 359 P G+GT++ P + V + G R ID A VYG E++VG I K+ V RE++ Sbjct: 47 PALGVGTFQD-PDSQEETVCQVLQRGMRLIDTARVYGVEQQVGRGI----KKSGVPREEI 101 Query: 360 FITSKLW-NTFHRPDLVRGALQETL 431 F+ +KLW N FH PD V A+ ++L Sbjct: 102 FLGTKLWCNDFH-PDDVERAVDDSL 125 >UniRef50_Q7XY49 Cluster: Mannose 6-phosphate reductase; n=1; Griffithsia japonica|Rep: Mannose 6-phosphate reductase - Griffithsia japonica (Red alga) Length = 174 Score = 97.9 bits (233), Expect = 3e-19 Identities = 47/89 (52%), Positives = 58/89 (65%) Frame = +3 Query: 180 PXFGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIKEGVVTREDL 359 P G GTWK+ E QAV A+ GYRHIDCA VY NE VG AI+ I GVV REDL Sbjct: 15 PLNGFGTWKASVEETEQAVTAALRAGYRHIDCAAVYWNEAAVGTAISKAISGGVVKREDL 74 Query: 360 FITSKLWNTFHRPDLVRGALQETLEQSEL 446 FITSK+WNT H D V + +++L+ ++ Sbjct: 75 FITSKVWNTCHATDKVVDSCRQSLKDHQV 103 Score = 43.6 bits (98), Expect = 0.007 Identities = 21/53 (39%), Positives = 30/53 (56%) Frame = +1 Query: 598 LVKSIGVSNFNSKQLERLLXHAXVKPVVNXVECHPYLNXKRLKEFCXXRGVXI 756 LV+ IGVSN++ L L +A +KP VN E H Y +L++ C GV + Sbjct: 110 LVRDIGVSNYSVALLVDTLNYARIKPSVNQCEAHVYFARPQLRDVCREFGVHL 162 >UniRef50_Q0IBY6 Cluster: Alcohol dehydrogenase; n=2; Chroococcales|Rep: Alcohol dehydrogenase - Synechococcus sp. (strain CC9311) Length = 336 Score = 97.5 bits (232), Expect = 4e-19 Identities = 44/85 (51%), Positives = 62/85 (72%) Frame = +3 Query: 180 PXFGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIKEGVVTREDL 359 P GLGT KS+ +V ++V++AI IGYRHIDCA +YGNE+EVG+AI I+ +TR +L Sbjct: 31 PLLGLGTGKSESRQVYKSVREAIKIGYRHIDCASIYGNEEEVGDAIRDAIQNHEITRSEL 90 Query: 360 FITSKLWNTFHRPDLVRGALQETLE 434 +ITSKLW+ H + V AL ++L+ Sbjct: 91 WITSKLWSNCHGKNHVEAALSQSLQ 115 Score = 90.2 bits (214), Expect = 6e-17 Identities = 46/112 (41%), Positives = 61/112 (54%) Frame = +1 Query: 436 NLNFQYLDLYLIHWPQAYKEDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIG 615 NL YL+LYLIHWP + + + F + + +TW+AME +GL K IG Sbjct: 116 NLGVDYLNLYLIHWPVGIRPEKT-FAESVDDLLTPEESPISETWEAMESTRDKGLTKHIG 174 Query: 616 VSNFNSKQLERLLXHAXVKPVVNXVECHPYLNXKRLKEFCXXRGVXIXXYSP 771 VSNF K+L++L+ H KP VN VE HP L L E+C + I YSP Sbjct: 175 VSNFTVKKLQQLVSHCKQKPEVNQVEHHPLLQQPTLIEYCASEEILITAYSP 226 >UniRef50_Q1YPE5 Cluster: Aldehyde reductase; n=7; Bacteria|Rep: Aldehyde reductase - gamma proteobacterium HTCC2207 Length = 330 Score = 97.1 bits (231), Expect = 5e-19 Identities = 43/92 (46%), Positives = 60/92 (65%) Frame = +3 Query: 180 PXFGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIKEGVVTREDL 359 P GLG WK QAV +AI +GYRH+D A YGNE++VGE I I EG+ +RE+L Sbjct: 18 PAVGLGLWKITQDSAAQAVYEAIKVGYRHLDSAADYGNEQQVGEGIARAIAEGLCSREEL 77 Query: 360 FITSKLWNTFHRPDLVRGALQETLEQSELSVL 455 +IT+KLWNT+HR + V A + +++ L + Sbjct: 78 WITTKLWNTYHRAEHVEAACRRSMDDLGLDYI 109 Score = 83.4 bits (197), Expect = 7e-15 Identities = 45/127 (35%), Positives = 70/127 (55%), Gaps = 9/127 (7%) Frame = +1 Query: 418 CRRPWNNLNFQYLDLYLIHWPQA--YKEDGSLFPT----DQSGKIQFSDVDYV---DTWK 570 CRR ++L Y+DLYL+H+P A Y + +P D S + ++D V +TW Sbjct: 97 CRRSMDDLGLDYIDLYLVHFPIALRYVDFNDRYPAEWIFDHSAEDPAMELDQVPLSETWG 156 Query: 571 AMEPLVKEGLVKSIGVSNFNSKQLERLLXHAXVKPVVNXVECHPYLNXKRLKEFCXXRGV 750 AME LV+ GLV+ IGV N+++ L L+ +A +KP + +E HPYL + L + Sbjct: 157 AMEQLVESGLVRQIGVCNYSAVLLHDLMSYARIKPAMLQIESHPYLTQEALLRTARSYNM 216 Query: 751 XIXXYSP 771 + +SP Sbjct: 217 AVTAFSP 223 >UniRef50_UPI00015B4912 Cluster: PREDICTED: similar to aldo-keto reductase; n=1; Nasonia vitripennis|Rep: PREDICTED: similar to aldo-keto reductase - Nasonia vitripennis Length = 353 Score = 96.3 bits (229), Expect = 9e-19 Identities = 50/114 (43%), Positives = 64/114 (56%), Gaps = 3/114 (2%) Frame = +1 Query: 439 LNFQYLDLYLIHWPQA--YKEDGSLFPTDQSGKIQF-SDVDYVDTWKAMEPLVKEGLVKS 609 L QYLD+YLIH P A +KED T++ G + + D + WK ME VKEG KS Sbjct: 125 LGLQYLDMYLIHAPFAVHHKEDSYELATNEDGSVVLDTQTDPIAVWKEMEKQVKEGRTKS 184 Query: 610 IGVSNFNSKQLERLLXHAXVKPVVNXVECHPYLNXKRLKEFCXXRGVXIXXYSP 771 IG+SNFN Q+ +L A +KP VE H Y K L EFC G+ + Y+P Sbjct: 185 IGLSNFNETQITNILKEAKIKPSNLQVEVHAYHQQKPLIEFCQKNGIIVTGYAP 238 Score = 54.0 bits (124), Expect = 5e-06 Identities = 31/93 (33%), Positives = 50/93 (53%) Frame = +3 Query: 177 FPXFGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIKEGVVTRED 356 FP GLGT + + A++ G HID ++VY NE+ +G+ + +G RED Sbjct: 39 FPIVGLGTHGLNEDVLETVLTGALEKGIGHIDTSFVYKNEETIGKVLKDWFAKG-GKRED 97 Query: 357 LFITSKLWNTFHRPDLVRGALQETLEQSELSVL 455 +F+TSKL + P+ V ++ +LE+ L L Sbjct: 98 IFVTSKLPYYDNHPESVEKYIKLSLEKLGLQYL 130 >UniRef50_A5AD50 Cluster: Putative uncharacterized protein; n=3; Magnoliophyta|Rep: Putative uncharacterized protein - Vitis vinifera (Grape) Length = 304 Score = 96.3 bits (229), Expect = 9e-19 Identities = 44/69 (63%), Positives = 51/69 (73%) Frame = +3 Query: 180 PXFGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIKEGVVTREDL 359 P GLGTW+S PG V QAV AI +GYRHIDCA VYGNE+E+G + +GVV REDL Sbjct: 17 PSVGLGTWQSDPGLVGQAVAIAIKVGYRHIDCAQVYGNEEEIGIVLKKLFDDGVVKREDL 76 Query: 360 FITSKLWNT 386 +ITSKLW T Sbjct: 77 WITSKLWCT 85 Score = 38.3 bits (85), Expect = 0.26 Identities = 21/49 (42%), Positives = 26/49 (53%), Gaps = 1/49 (2%) Frame = +1 Query: 628 NSKQLERL-LXHAXVKPVVNXVECHPYLNXKRLKEFCXXRGVXIXXYSP 771 +S L RL L A V P V VECHP +L FC +GV + +SP Sbjct: 141 HSMILARLELLVARVPPAVIQVECHPSWQQSKLHAFCKSKGVHLTGFSP 189 >UniRef50_A3C1Z7 Cluster: Putative uncharacterized protein; n=2; Oryza sativa (japonica cultivar-group)|Rep: Putative uncharacterized protein - Oryza sativa subsp. japonica (Rice) Length = 288 Score = 96.3 bits (229), Expect = 9e-19 Identities = 48/119 (40%), Positives = 66/119 (55%), Gaps = 2/119 (1%) Frame = +1 Query: 421 RRPWNNLNFQYLDLYLIHWPQAYK--EDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKE 594 RR + +YLDLYLIH+P + + ED + + +D WK ME + Sbjct: 99 RRALRKMQMEYLDLYLIHFPVSMRLAEDPESMTYSKDDLVM---MDMEGVWKEMEECQRL 155 Query: 595 GLVKSIGVSNFNSKQLERLLXHAXVKPVVNXVECHPYLNXKRLKEFCXXRGVXIXXYSP 771 GL K+IGVSNF+ K+LE LL A + P N VE HPY +L+EFC +G+ + YSP Sbjct: 156 GLTKAIGVSNFSCKKLETLLSFATISPAANQVEVHPYCRQNKLREFCKEKGIQLCAYSP 214 Score = 62.9 bits (146), Expect = 1e-08 Identities = 35/98 (35%), Positives = 53/98 (54%), Gaps = 6/98 (6%) Frame = +3 Query: 180 PXFGLGTWK-----SKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIKEGVV 344 P G+GT + P V V AI+ GYRH D A VY E +G+A+ ++ G+V Sbjct: 13 PRVGMGTASFPLGATDPSTVKDVVLRAIEAGYRHFDTAAVYQTEAILGDAVAEAVRAGLV 72 Query: 345 -TREDLFITSKLWNTFHRPDLVRGALQETLEQSELSVL 455 +R++L+ITSKLW P V +L+ L + ++ L Sbjct: 73 ASRDELYITSKLWVAHAHPGHVLPSLRRALRKMQMEYL 110 >UniRef50_P38715 Cluster: NADPH-dependent aldose reductase GRE3; n=39; cellular organisms|Rep: NADPH-dependent aldose reductase GRE3 - Saccharomyces cerevisiae (Baker's yeast) Length = 327 Score = 96.3 bits (229), Expect = 9e-19 Identities = 46/92 (50%), Positives = 57/92 (61%) Frame = +3 Query: 180 PXFGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIKEGVVTREDL 359 P GLG WK + +AI +GYR D A YGNEKEVGE I I EG+V+R+D+ Sbjct: 14 PLVGLGCWKIDKKVCANQIYEAIKLGYRLFDGACDYGNEKEVGEGIRKAISEGLVSRKDI 73 Query: 360 FITSKLWNTFHRPDLVRGALQETLEQSELSVL 455 F+ SKLWN FH PD V+ AL++TL L L Sbjct: 74 FVVSKLWNNFHHPDHVKLALKKTLSDMGLDYL 105 Score = 86.2 bits (204), Expect = 1e-15 Identities = 47/126 (37%), Positives = 68/126 (53%), Gaps = 10/126 (7%) Frame = +1 Query: 421 RRPWNNLNFQYLDLYLIHWPQAYK--------EDGSLFPTD--QSGKIQFSDVDYVDTWK 570 ++ +++ YLDLY IH+P A+K G D + G I + V +DT++ Sbjct: 94 KKTLSDMGLDYLDLYYIHFPIAFKYVPFEEKYPPGFYTGADDEKKGHITEAHVPIIDTYR 153 Query: 571 AMEPLVKEGLVKSIGVSNFNSKQLERLLXHAXVKPVVNXVECHPYLNXKRLKEFCXXRGV 750 A+E V EGL+KSIGVSNF ++ LL +KPV +E HPYL + L EFC + Sbjct: 154 ALEECVDEGLIKSIGVSNFQGSLIQDLLRGCRIKPVALQIEHHPYLTQEHLVEFCKLHDI 213 Query: 751 XIXXYS 768 + YS Sbjct: 214 QVVAYS 219 >UniRef50_Q8SSK6 Cluster: ALDOSE REDUCTASE; n=1; Encephalitozoon cuniculi|Rep: ALDOSE REDUCTASE - Encephalitozoon cuniculi Length = 301 Score = 95.9 bits (228), Expect = 1e-18 Identities = 49/118 (41%), Positives = 63/118 (53%), Gaps = 2/118 (1%) Frame = +1 Query: 421 RRPWNNLNFQYLDLYLIHWPQAYKE--DGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKE 594 RR N+L Y+DLYLIHWP + DG++ + K D V WK ME LV Sbjct: 94 RRSLNDLQMDYVDLYLIHWPVTFDPAPDGTVESCGK--KYNVGKFDAVGVWKKMEALVDL 151 Query: 595 GLVKSIGVSNFNSKQLERLLXHAXVKPVVNXVECHPYLNXKRLKEFCXXRGVXIXXYS 768 GL KSIG+SNF E++L + P +E HPYLN K L EF +G+ + YS Sbjct: 152 GLAKSIGISNFGKANTEKILGTCRICPAAIQIELHPYLNQKELVEFMKSKGIQVISYS 209 Score = 92.3 bits (219), Expect = 1e-17 Identities = 40/72 (55%), Positives = 52/72 (72%), Gaps = 1/72 (1%) Frame = +3 Query: 180 PXFGLGTWKSKPGEVTQ-AVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIKEGVVTRED 356 P GLGTW + V + A+++A+ +GYRHID A++YGNEK +G + EGVV R+D Sbjct: 15 PTVGLGTWGMEDEAVLEGAIRNALSLGYRHIDTAFIYGNEKMIGNILKKLFDEGVVQRKD 74 Query: 357 LFITSKLWNTFH 392 LFITSKLWNTFH Sbjct: 75 LFITSKLWNTFH 86 >UniRef50_A2QVE5 Cluster: Similarity: shows similarity to several dehydrogenases of different specificities; n=4; Pezizomycotina|Rep: Similarity: shows similarity to several dehydrogenases of different specificities - Aspergillus niger Length = 381 Score = 95.5 bits (227), Expect = 2e-18 Identities = 46/93 (49%), Positives = 60/93 (64%), Gaps = 1/93 (1%) Frame = +3 Query: 180 PXFGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIKE-GVVTRED 356 P G GTW+S PG+V AV +A+ GYRH+D A +Y N++EV E I K+ + RED Sbjct: 16 PQLGFGTWQSAPGQVGDAVYEALKAGYRHLDLATIYQNQREVAEGIKRAYKDVPGLKRED 75 Query: 357 LFITSKLWNTFHRPDLVRGALQETLEQSELSVL 455 +FITSKLWN+ H P +V AL E L + EL L Sbjct: 76 IFITSKLWNSQHDPAVVEKALDECLAELELDYL 108 Score = 87.0 bits (206), Expect = 6e-16 Identities = 44/116 (37%), Positives = 60/116 (51%), Gaps = 6/116 (5%) Frame = +1 Query: 439 LNFQYLDLYLIHWPQAYKEDGSLFPTDQSGKIQFSDV------DYVDTWKAMEPLVKEGL 600 L YLDLYL+HWP ++ LFP + ++ DV VDTWKAM L K Sbjct: 103 LELDYLDLYLVHWPVSFTTGSELFPLVKDSSVEGGDVVINDDISIVDTWKAMTQLPKSK- 161 Query: 601 VKSIGVSNFNSKQLERLLXHAXVKPVVNXVECHPYLNXKRLKEFCXXRGVXIXXYS 768 +++GVSN LE ++ V P VN +E HP L L E+C +G+ + YS Sbjct: 162 ARTVGVSNHMIPHLEAIINATGVVPAVNQIERHPVLQSNELIEYCQKKGIHVTAYS 217 >UniRef50_P26690 Cluster: NAD(P)H-dependent 6'-deoxychalcone synthase; n=3; Papilionoideae|Rep: NAD(P)H-dependent 6'-deoxychalcone synthase - Glycine max (Soybean) Length = 315 Score = 95.5 bits (227), Expect = 2e-18 Identities = 48/119 (40%), Positives = 69/119 (57%) Frame = +1 Query: 421 RRPWNNLNFQYLDLYLIHWPQAYKEDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGL 600 R+ L +YLDLYLIHWP + + FP + + F D W++ME K GL Sbjct: 104 RKSLKTLQLEYLDLYLIHWPLSSQPGKFSFPIEVEDLLPF---DVKGVWESMEECQKLGL 160 Query: 601 VKSIGVSNFNSKQLERLLXHAXVKPVVNXVECHPYLNXKRLKEFCXXRGVXIXXYSPPR 777 K+IGVSNF+ K+L+ LL A ++PVV+ VE + K+L+EFC G+ + +SP R Sbjct: 161 TKAIGVSNFSVKKLQNLLSVATIRPVVDQVEMNLAWQQKKLREFCKENGIIVTAFSPLR 219 Score = 76.6 bits (180), Expect = 8e-13 Identities = 39/101 (38%), Positives = 63/101 (62%), Gaps = 2/101 (1%) Frame = +3 Query: 159 STMEXLFPXFGLGTWK--SKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIK 332 S+ + P G+G+ + + +A+ +A+ GYRH D A YG+E+ +GEA+ I Sbjct: 15 SSAQQRMPVVGMGSAPDFTCKKDTKEAIIEAVKQGYRHFDTAAAYGSEQALGEALKEAIH 74 Query: 333 EGVVTREDLFITSKLWNTFHRPDLVRGALQETLEQSELSVL 455 G+V+R+DLF+TSKLW T + P LV AL+++L+ +L L Sbjct: 75 LGLVSRQDLFVTSKLWVTENHPHLVLPALRKSLKTLQLEYL 115 >UniRef50_Q68ST9 Cluster: Reductase AKOR2; n=2; Pleurotus djamor|Rep: Reductase AKOR2 - Pleurotus djamor Length = 306 Score = 95.1 bits (226), Expect = 2e-18 Identities = 46/114 (40%), Positives = 70/114 (61%), Gaps = 2/114 (1%) Frame = +1 Query: 436 NLNFQYLDLYLIHWPQ-AYKEDGSLFPTDQSGKIQFSDVDYV-DTWKAMEPLVKEGLVKS 609 NL +Y+DLYL+H+PQ + ++ + FP + G I+ + + D W +E L+ G VK+ Sbjct: 99 NLGTEYIDLYLVHFPQRVFYDETTDFPRNPDGSIKVVNSPTLNDVWADVETLLDTGKVKA 158 Query: 610 IGVSNFNSKQLERLLXHAXVKPVVNXVECHPYLNXKRLKEFCXXRGVXIXXYSP 771 IGVSN++ K LE LL A V P VN VE HP+L +L +C +G+ + Y+P Sbjct: 159 IGVSNYSIKTLEELLKTAKVVPAVNQVELHPFLAQSKLLAYCKEKGIAVTAYTP 212 Score = 54.4 bits (125), Expect = 4e-06 Identities = 37/90 (41%), Positives = 47/90 (52%), Gaps = 5/90 (5%) Frame = +3 Query: 180 PXFGLGTWKSKPGEVTQAVKD----AIDIGYRHIDCAYVYGNEKEVGEAITSKIKEGVVT 347 P LG W E K+ A+ GYRHID A +Y EK VG A I+E + Sbjct: 16 PALALGGWAGLTEEERTQAKEWFLTALKSGYRHIDTAQIYYTEKSVGNA----IRESGIP 71 Query: 348 REDLFITSKL-WNTFHRPDLVRGALQETLE 434 RE+LFIT+KL WN R V + Q++LE Sbjct: 72 REELFITTKLPWNHHSR---VAESFQKSLE 98 >UniRef50_Q9Y020 Cluster: 3-dehydroecdysone 3beta-reductase precursor; n=1; Spodoptera littoralis|Rep: 3-dehydroecdysone 3beta-reductase precursor - Spodoptera littoralis (Egyptian cotton leafworm) Length = 345 Score = 93.1 bits (221), Expect = 9e-18 Identities = 43/84 (51%), Positives = 57/84 (67%) Frame = +3 Query: 195 GTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIKEGVVTREDLFITSK 374 G SK ++ V AID+GYRH D A +Y E EVGEAI KI EGV+ RED+F+T+K Sbjct: 48 GAVTSKDKQLRNVVMQAIDLGYRHFDTAAIYNTEAEVGEAIRMKIDEGVIKREDVFLTTK 107 Query: 375 LWNTFHRPDLVRGALQETLEQSEL 446 LWNT H+ + V A++ETL ++ L Sbjct: 108 LWNTHHKREQVAVAMKETLNKTGL 131 Score = 88.6 bits (210), Expect = 2e-16 Identities = 46/125 (36%), Positives = 65/125 (52%) Frame = +1 Query: 397 RTWCAVPCRRPWNNLNFQYLDLYLIHWPQAYKEDGSLFPTDQSGKIQFSDVDYVDTWKAM 576 R AV + N Y+DL+L+HWP A ED S S+ DY++TW+A Sbjct: 115 REQVAVAMKETLNKTGLDYVDLFLMHWPIALNEDYS-----------HSNTDYLETWRAT 163 Query: 577 EPLVKEGLVKSIGVSNFNSKQLERLLXHAXVKPVVNXVECHPYLNXKRLKEFCXXRGVXI 756 E +VK G KSIG+SNFN Q+ +L +KPV +E HP + + L + G+ + Sbjct: 164 EEMVKLGYTKSIGLSNFNKLQVATVLQECTIKPVALQIEVHPQIIQEDLITYAKDEGIIV 223 Query: 757 XXYSP 771 YSP Sbjct: 224 MGYSP 228 >UniRef50_Q2UGR1 Cluster: Aldo/keto reductase family proteins; n=2; Ascomycota|Rep: Aldo/keto reductase family proteins - Aspergillus oryzae Length = 323 Score = 93.1 bits (221), Expect = 9e-18 Identities = 45/114 (39%), Positives = 66/114 (57%), Gaps = 2/114 (1%) Frame = +1 Query: 436 NLNFQYLDLYLIHWPQAYKEDG-SLFPTDQSGK-IQFSDVDYVDTWKAMEPLVKEGLVKS 609 +L YLDLYLIHWP A++ +L P D K + ++V DTW A+E LV+ ++S Sbjct: 97 DLQTDYLDLYLIHWPVAFEHTNETLTPIDPVTKRFRLANVPIADTWAALEKLVEAKKIRS 156 Query: 610 IGVSNFNSKQLERLLXHAXVKPVVNXVECHPYLNXKRLKEFCXXRGVXIXXYSP 771 IG+SNF +++ LL A + P VN +E HPYL L ++ + + YSP Sbjct: 157 IGISNFTQDKIDDLLKTAKIPPAVNQIEAHPYLQQPGLHKYLKEKNILSVAYSP 210 Score = 90.2 bits (214), Expect = 6e-17 Identities = 46/92 (50%), Positives = 56/92 (60%) Frame = +3 Query: 180 PXFGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIKEGVVTREDL 359 P GLGTW SKP EV AV+ A+ GYRHID A Y NE EVG K+ V R+ + Sbjct: 16 PAIGLGTWLSKPHEVENAVEAALRAGYRHIDAAACYQNENEVGNG----WKKSGVPRDQI 71 Query: 360 FITSKLWNTFHRPDLVRGALQETLEQSELSVL 455 FITSKLWNT H P+ V A+ +TL+ + L Sbjct: 72 FITSKLWNTHHHPEHVEEAVNKTLKDLQTDYL 103 >UniRef50_Q9VHX4 Cluster: CG2767-PA; n=4; Endopterygota|Rep: CG2767-PA - Drosophila melanogaster (Fruit fly) Length = 329 Score = 92.7 bits (220), Expect = 1e-17 Identities = 47/120 (39%), Positives = 69/120 (57%), Gaps = 3/120 (2%) Frame = +1 Query: 421 RRPWNNLNFQYLDLYLIHWPQAYK--EDGSLFPTDQSGKIQFS-DVDYVDTWKAMEPLVK 591 ++ +L Y+DLYL+H P EDGS F D+ G ++ ++ W AME LV+ Sbjct: 96 KKSLEDLQLDYVDLYLVHTPFTININEDGS-FKLDKEGLMEVDVTTNHAAIWVAMEALVE 154 Query: 592 EGLVKSIGVSNFNSKQLERLLXHAXVKPVVNXVECHPYLNXKRLKEFCXXRGVXIXXYSP 771 +GL KSIGVSNF+ Q+ RLL + ++P N +E H YL + L +FC + + YSP Sbjct: 155 KGLTKSIGVSNFSKDQVARLLKNCKIRPANNQIEHHVYLQQRDLVDFCKSENITVTAYSP 214 Score = 79.4 bits (187), Expect = 1e-13 Identities = 36/89 (40%), Positives = 55/89 (61%) Frame = +3 Query: 180 PXFGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIKEGVVTREDL 359 P G+GTW++ E+ A+ A++ GYRHID A VYGNEK +G + + G V RE+L Sbjct: 16 PVIGIGTWQASDEEIETAIDAALEAGYRHIDTAPVYGNEKAIGRVLKRWLDAGKVKREEL 75 Query: 360 FITSKLWNTFHRPDLVRGALQETLEQSEL 446 FI +K+ +RP V ++++LE +L Sbjct: 76 FIVTKVPPVSNRPHEVEPTIKKSLEDLQL 104 >UniRef50_A2FPE2 Cluster: Oxidoreductase, aldo/keto reductase family protein; n=3; Trichomonas vaginalis G3|Rep: Oxidoreductase, aldo/keto reductase family protein - Trichomonas vaginalis G3 Length = 309 Score = 92.7 bits (220), Expect = 1e-17 Identities = 47/120 (39%), Positives = 69/120 (57%), Gaps = 4/120 (3%) Frame = +1 Query: 421 RRPWNNLNFQYLDLYLIHWPQAY--KEDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKE 594 ++ L +YLDL L+HW A+ +ED P D++GKI ++D ++TWKAME Sbjct: 87 KKTLKELKLEYLDLVLVHWACAFQSREDDEYLPRDETGKIITENIDILETWKAMEECYNL 146 Query: 595 GLVKSIGVSNFNSKQLERLLXHAXVK--PVVNXVECHPYLNXKRLKEFCXXRGVXIXXYS 768 GL K IGVSNF+ +QLER+ VK P N VE H YL + + ++ R + + Y+ Sbjct: 147 GLAKHIGVSNFSIEQLERMRYDPGVKIQPYCNQVESHMYLQQQPMLDYLTQRKMYMISYT 206 Score = 89.0 bits (211), Expect = 1e-16 Identities = 47/110 (42%), Positives = 70/110 (63%), Gaps = 2/110 (1%) Frame = +3 Query: 174 LFPXFGLGTWKSK-PGEVTQAVKDAI-DIGYRHIDCAYVYGNEKEVGEAITSKIKEGVVT 347 + P GLGT+ ++ P + AV AI D GYRH+DCA Y N++ +GEA++ +G V Sbjct: 3 VIPSIGLGTFLAEDPAALKAAVHSAIEDSGYRHVDCAAYYKNQEIIGEALSEIFAKGQVK 62 Query: 348 REDLFITSKLWNTFHRPDLVRGALQETLEQSELSVLGSVPDTLAPGLQGR 497 RE+++ITSK+WNT HRPDL+ +++TL++ +L L V A Q R Sbjct: 63 REEVWITSKVWNTKHRPDLLVKDVKKTLKELKLEYLDLVLVHWACAFQSR 112 >UniRef50_UPI0000519CC2 Cluster: PREDICTED: similar to CG2767-PA; n=1; Apis mellifera|Rep: PREDICTED: similar to CG2767-PA - Apis mellifera Length = 321 Score = 92.3 bits (219), Expect = 1e-17 Identities = 46/114 (40%), Positives = 68/114 (59%), Gaps = 2/114 (1%) Frame = +1 Query: 436 NLNFQYLDLYLIHWPQAYKEDGS-LFPTDQSGKIQFSD-VDYVDTWKAMEPLVKEGLVKS 609 NL +YLDLYLIH P +++ G L P D++G I+ + ++V+ W ME VK G K+ Sbjct: 100 NLRLEYLDLYLIHVPIGFEKVGDILHPFDENGHIRLDNSTNHVEIWAEMEKQVKCGRTKA 159 Query: 610 IGVSNFNSKQLERLLXHAXVKPVVNXVECHPYLNXKRLKEFCXXRGVXIXXYSP 771 IG+SNFN Q++R+L + +K + +E H Y K L +FC + I YSP Sbjct: 160 IGLSNFNISQIKRILKNTKMKISMLQIELHVYFQQKELVKFCKQENIPITAYSP 213 Score = 64.9 bits (151), Expect = 3e-09 Identities = 32/94 (34%), Positives = 52/94 (55%) Frame = +3 Query: 174 LFPXFGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIKEGVVTRE 353 L P G GTW+++ E+ A+ A++ GYRHID A Y NEK +G+ + + + R Sbjct: 13 LMPIIGFGTWQAQEKELEDALNIALEAGYRHIDTATSYENEKVIGDVLKNWFDSKKLKRS 72 Query: 354 DLFITSKLWNTFHRPDLVRGALQETLEQSELSVL 455 D+FI +KL +R + V ++ +L+ L L Sbjct: 73 DIFIVTKLPAVGNRAEDVEKWIKTSLQNLRLEYL 106 >UniRef50_A7PNI3 Cluster: Chromosome chr1 scaffold_22, whole genome shotgun sequence; n=2; Vitis vinifera|Rep: Chromosome chr1 scaffold_22, whole genome shotgun sequence - Vitis vinifera (Grape) Length = 360 Score = 92.3 bits (219), Expect = 1e-17 Identities = 44/113 (38%), Positives = 65/113 (57%), Gaps = 1/113 (0%) Frame = +1 Query: 436 NLNFQYLDLYLIHWPQAYKEDGSLFPTDQSGKIQFSDVDYVD-TWKAMEPLVKEGLVKSI 612 NL YLDLYL+HWP + P SG ++ + WKAME L++ GLV++I Sbjct: 105 NLGVTYLDLYLMHWPDITAFGDATDPPSNSGNDHRQFLNRLKKAWKAMEGLIELGLVRAI 164 Query: 613 GVSNFNSKQLERLLXHAXVKPVVNXVECHPYLNXKRLKEFCXXRGVXIXXYSP 771 GVSNF +Q++ LL A + P VN V+ HP+ L +FC +G+ + ++P Sbjct: 165 GVSNFGVQQIKELLKFAKIVPAVNQVKLHPFWRQDELVKFCQSKGIHVSAHTP 217 Score = 79.8 bits (188), Expect = 9e-14 Identities = 39/92 (42%), Positives = 59/92 (64%) Frame = +3 Query: 180 PXFGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIKEGVVTREDL 359 P GLGTW+S +AVK A+ GYR IDCA++YGNE EVGEA+ G + RED+ Sbjct: 21 PAIGLGTWQSGGDLCVEAVKRALSEGYRQIDCAHLYGNEVEVGEALAEAF-NGSLKREDV 79 Query: 360 FITSKLWNTFHRPDLVRGALQETLEQSELSVL 455 F+TSKL+ T + + + +++ +L+ ++ L Sbjct: 80 FLTSKLYCTMNSLNKIENSVRVSLKNLGVTYL 111 >UniRef50_Q0CLQ2 Cluster: Putative uncharacterized protein; n=1; Aspergillus terreus NIH2624|Rep: Putative uncharacterized protein - Aspergillus terreus (strain NIH 2624) Length = 301 Score = 92.3 bits (219), Expect = 1e-17 Identities = 47/92 (51%), Positives = 57/92 (61%) Frame = +3 Query: 180 PXFGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIKEGVVTREDL 359 P GLGTW SKP EV AV+ A+ +GYRHID A Y NE EVG K+ V R+ + Sbjct: 16 PAVGLGTWLSKPHEVENAVETALRLGYRHIDAAACYLNENEVGNG----WKKSGVPRDQI 71 Query: 360 FITSKLWNTFHRPDLVRGALQETLEQSELSVL 455 FITSKLWNT H PD V A+ +TL+ + L Sbjct: 72 FITSKLWNTHHHPDHVEEAVNKTLKDLQTDYL 103 Score = 80.2 bits (189), Expect = 6e-14 Identities = 41/105 (39%), Positives = 60/105 (57%), Gaps = 4/105 (3%) Frame = +1 Query: 469 IHWPQAYKEDG-SLFPTDQ-SGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQL 642 IHWP A++ +L P D S + + +++ DTW A+E LV G V+SIGVSNF +++ Sbjct: 128 IHWPVAFEHTNETLTPIDPVSKRFRLANIPIADTWAALEKLVDAGKVRSIGVSNFTIEKI 187 Query: 643 ERLLXHAXVKPVVNXVECHPYLNXKRLKEFCXXR--GVXIXXYSP 771 E LL A + P VN +E HPYL L ++ + + YSP Sbjct: 188 EELLKTARIPPAVNQIEAHPYLQQPALHKYLKEKVTNILSVAYSP 232 >UniRef50_Q4FY75 Cluster: Aldo-keto reductase-like protein; n=5; Trypanosomatidae|Rep: Aldo-keto reductase-like protein - Leishmania major strain Friedlin Length = 372 Score = 91.5 bits (217), Expect = 3e-17 Identities = 43/92 (46%), Positives = 53/92 (57%) Frame = +3 Query: 180 PXFGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIKEGVVTREDL 359 P G GT++ E T AV A+ GYRH+DCA YGNE VGEA+ ++ REDL Sbjct: 31 PQLGFGTYRLPVSEATDAVAFALSCGYRHVDCAKAYGNEAAVGEALAQALRTRCTRREDL 90 Query: 360 FITSKLWNTFHRPDLVRGALQETLEQSELSVL 455 F+TSKLW T PD V A + TL +L L Sbjct: 91 FVTSKLWPTDQHPDHVEAACRATLAALQLDYL 122 Score = 63.7 bits (148), Expect = 6e-09 Identities = 42/107 (39%), Positives = 53/107 (49%), Gaps = 12/107 (11%) Frame = +1 Query: 418 CRRPWNNLNFQYLDLYLIHWPQAYKE------DGSLFPTDQSGKIQF-SDVDYVDTWKAM 576 CR L YLDLYLIHWP + D +P + G + V +DTW AM Sbjct: 110 CRATLAALQLDYLDLYLIHWPVCMRHTPHWTSDEDRYPRHRDGTPAIDTSVTLLDTWTAM 169 Query: 577 EPLVKEGLVKSIGVSNFNSKQLERLLXH-AXVK----PVVNXVECHP 702 LV GLVKSIG++N + + L+ A K PV+N VE HP Sbjct: 170 NRLVDRGLVKSIGLANCTTAHVNDLVKAVAEAKLAHLPVLNQVEHHP 216 >UniRef50_P82125 Cluster: 1,5-anhydro-D-fructose reductase; n=1; Sus scrofa|Rep: 1,5-anhydro-D-fructose reductase - Sus scrofa (Pig) Length = 206 Score = 91.5 bits (217), Expect = 3e-17 Identities = 45/66 (68%), Positives = 50/66 (75%), Gaps = 1/66 (1%) Frame = +3 Query: 180 PXFGLGTWKSKPG-EVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIKEGVVTRED 356 P GLGTW++ PG EVT+AVK AID GYRH D AY+Y NE EVG I +KI EGVV RED Sbjct: 3 PVLGLGTWQAAPGGEVTEAVKVAIDTGYRHPDSAYLYHNEDEVGVGIQAKIDEGVVRRED 62 Query: 357 LFITSK 374 LFI SK Sbjct: 63 LFIVSK 68 Score = 36.7 bits (81), Expect(2) = 0.001 Identities = 16/35 (45%), Positives = 20/35 (57%) Frame = +1 Query: 451 YLDLYLIHWPQAYKEDGSLFPTDQSGKIQFSDVDY 555 YLDL IHWP +K P D+SG I S+ D+ Sbjct: 72 YLDLXNIHWPMQFKPGEVDLPVDRSGMIVASNTDF 106 Score = 29.1 bits (62), Expect(2) = 0.001 Identities = 14/33 (42%), Positives = 16/33 (48%) Frame = +1 Query: 673 PVVNXVECHPYLNXKRLKEFCXXRGVXIXXYSP 771 PV N +E HPYL K F R V + Y P Sbjct: 109 PVTNQIESHPYLTQK--ISFXQSRNVSVTAYRP 139 >UniRef50_Q5T2L2 Cluster: Aldo-keto reductase family 1 member C-like protein 1; n=14; Eutheria|Rep: Aldo-keto reductase family 1 member C-like protein 1 - Homo sapiens (Human) Length = 302 Score = 91.1 bits (216), Expect = 3e-17 Identities = 43/89 (48%), Positives = 60/89 (67%), Gaps = 3/89 (3%) Frame = +3 Query: 180 PXFGLGTWK---SKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIKEGVVTR 350 P G GT+ + + +A K AID+G+RHID AY+Y NE+EVG+AI KI +G V R Sbjct: 20 PVLGFGTYAPDHTPKSQAAEATKVAIDVGFRHIDSAYLYQNEEEVGQAIWEKIADGTVKR 79 Query: 351 EDLFITSKLWNTFHRPDLVRGALQETLEQ 437 E++F T KLW TF R +LV AL+ +L++ Sbjct: 80 EEIFYTIKLWATFFRAELVHPALERSLKK 108 Score = 59.7 bits (138), Expect = 1e-07 Identities = 42/117 (35%), Positives = 53/117 (45%), Gaps = 2/117 (1%) Frame = +1 Query: 424 RPWNNLNFQYLDLYLIHWPQAYKEDGS-LFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGL 600 R L Y+DL++IH P A K+ G L P D SG+I V+ DTW+ L K GL Sbjct: 104 RSLKKLGPDYVDLFIIHVPFAMKQPGKELLPKDASGEIILETVELCDTWELELILNKPGL 163 Query: 601 VKSIGVSNFNSKQLERLLXHAXVKPVVN-XVECHPYLNXKRLKEFCXXRGVXIXXYS 768 KP N VECHPYLN +L EFC + + + YS Sbjct: 164 ---------------------RYKPTCNQVVECHPYLNQSKLLEFCKSKDIVLVAYS 199 >UniRef50_Q6NII7 Cluster: Putative oxidoreductase; n=2; Corynebacterium|Rep: Putative oxidoreductase - Corynebacterium diphtheriae Length = 290 Score = 90.2 bits (214), Expect = 6e-17 Identities = 40/92 (43%), Positives = 59/92 (64%) Frame = +3 Query: 180 PXFGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIKEGVVTREDL 359 P G GT+K + + +AV+ AI++GYRHID A +Y NE+EVG A+ I G V R++L Sbjct: 23 PAIGFGTYKLREQDAYRAVRSAIEVGYRHIDTASLYKNEEEVGRAVADAITAGEVARDEL 82 Query: 360 FITSKLWNTFHRPDLVRGALQETLEQSELSVL 455 FIT+K+WN H L + + QE+L + L + Sbjct: 83 FITTKVWNDMHGDQLTQRSFQESLHRLGLDYI 114 Score = 41.9 bits (94), Expect = 0.021 Identities = 29/113 (25%), Positives = 51/113 (45%) Frame = +1 Query: 433 NNLNFQYLDLYLIHWPQAYKEDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSI 612 + L Y+D ++HWP +P Q G YV+++ A+ + G ++S+ Sbjct: 107 HRLGLDYIDCCMVHWP---------WP--QKGL-------YVESFAALAKIQGLGQLQSV 148 Query: 613 GVSNFNSKQLERLLXHAXVKPVVNXVECHPYLNXKRLKEFCXXRGVXIXXYSP 771 V+NF + L ++ + PV+N VE HP + + GV +SP Sbjct: 149 AVANFYPEVLREIVAETGIAPVLNQVELHPGFSQAEQRAVDRELGVVTEAWSP 201 >UniRef50_Q05KR9 Cluster: Benzil reductase; n=5; Bacillales|Rep: Benzil reductase - Bacillus subtilis Length = 276 Score = 90.2 bits (214), Expect = 6e-17 Identities = 48/111 (43%), Positives = 64/111 (57%) Frame = +1 Query: 439 LNFQYLDLYLIHWPQAYKEDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGV 618 L YLDLYLIHWP GK + Y DTW+A+E L K+G +++IGV Sbjct: 101 LQLDYLDLYLIHWP---------------GKDK-----YKDTWRALEKLYKDGKIRAIGV 140 Query: 619 SNFNSKQLERLLXHAXVKPVVNXVECHPYLNXKRLKEFCXXRGVXIXXYSP 771 SNF LE LL A +KP+VN VE HP L K L+++C +G+ + +SP Sbjct: 141 SNFQVHHLEELLKDAEIKPMVNQVEFHPRLTQKELRDYCKAQGIQLEAWSP 191 Score = 74.1 bits (174), Expect = 4e-12 Identities = 43/93 (46%), Positives = 57/93 (61%), Gaps = 1/93 (1%) Frame = +3 Query: 180 PXFGLGTWKSKPG-EVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIKEGVVTRED 356 P FGLG +K + G E T++VK AI GYR ID A +Y NE+ VG I KE V RE+ Sbjct: 18 PWFGLGVFKVENGNEATESVKAAIKNGYRSIDTAAIYKNEEGVGIGI----KESGVAREE 73 Query: 357 LFITSKLWNTFHRPDLVRGALQETLEQSELSVL 455 LFITSK+WN + A +++LE+ +L L Sbjct: 74 LFITSKVWNEDQGYETTLAAFEKSLERLQLDYL 106 >UniRef50_Q4PDR0 Cluster: Putative uncharacterized protein; n=1; Ustilago maydis|Rep: Putative uncharacterized protein - Ustilago maydis (Smut fungus) Length = 339 Score = 90.2 bits (214), Expect = 6e-17 Identities = 45/119 (37%), Positives = 66/119 (55%), Gaps = 6/119 (5%) Frame = +1 Query: 433 NNLNFQYLDLYLIHWPQAYKEDGSLFPTDQSGKIQFSD---VDYVDTWKAMEPLV---KE 594 N L Y+DL+L+HWPQ + +D F T +S ++ + +TW ME + + Sbjct: 100 NELGIDYIDLWLLHWPQGFTKDDGGFGTGESFGLEHQKHLGPTFNETWAKMEDVFLNSHK 159 Query: 595 GLVKSIGVSNFNSKQLERLLXHAXVKPVVNXVECHPYLNXKRLKEFCXXRGVXIXXYSP 771 G VK+IGVSNF+ K LE L + V P VN +E HPYL L ++C + + + YSP Sbjct: 160 GKVKAIGVSNFSIKNLEILAKTSKVTPAVNQIEAHPYLPEHELVKYCKHKSIHVTAYSP 218 Score = 60.5 bits (140), Expect = 6e-08 Identities = 40/98 (40%), Positives = 57/98 (58%), Gaps = 5/98 (5%) Frame = +3 Query: 180 PXFGLGTWKSKPG-----EVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIKEGVV 344 P G+G W+ +PG E+ A+ AI +GYRH+D A Y NE EVG+A +++ V Sbjct: 17 PSVGMGCWQGQPGPGRDNELVDALVRAIKVGYRHLDTATGYRNEAEVGQA----VRQSGV 72 Query: 345 TREDLFITSKLWNTFHRPDLVRGALQETLEQSELSVLG 458 R ++F+T+KL RP V +QE LE S L+ LG Sbjct: 73 ARSEIFVTTKL-----RPGGVHDVVQE-LENS-LNELG 103 >UniRef50_Q7G764 Cluster: Probable NAD(P)H-dependent oxidoreductase 1; n=32; Eukaryota|Rep: Probable NAD(P)H-dependent oxidoreductase 1 - Oryza sativa subsp. japonica (Rice) Length = 321 Score = 90.2 bits (214), Expect = 6e-17 Identities = 46/117 (39%), Positives = 66/117 (56%) Frame = +1 Query: 421 RRPWNNLNFQYLDLYLIHWPQAYKEDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGL 600 R NL Y+DL L+HWP + FP + + D++ V W+ ME + GL Sbjct: 101 RETLRNLGMDYVDLLLVHWPVSLTPGNYDFPFPKEVILPSFDMEGV--WRGMEECHRLGL 158 Query: 601 VKSIGVSNFNSKQLERLLXHAXVKPVVNXVECHPYLNXKRLKEFCXXRGVXIXXYSP 771 ++IGVSNF++K+LE+LL A V+P VN VE +P + L+E C GV + YSP Sbjct: 159 ARAIGVSNFSAKKLEQLLSLAAVRPAVNQVEVNPMWQQRTLREVCRREGVQLCGYSP 215 Score = 61.7 bits (143), Expect = 2e-08 Identities = 38/110 (34%), Positives = 59/110 (53%), Gaps = 8/110 (7%) Frame = +3 Query: 180 PXFGLGTWK---SKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIKEGVV-T 347 P G+GT + + T A+ AI++GYRH D A +Y E VGEA+ ++ G++ + Sbjct: 17 PRVGMGTAAFPFTSSEDTTAAMLRAIELGYRHFDTARIYATEGCVGEAVAEAVRRGLIAS 76 Query: 348 REDLFITSKLWNTFHRPDLVRGALQETLEQSELS----VLGSVPDTLAPG 485 R D+F+TSK+W + V A +ETL + +L P +L PG Sbjct: 77 RADVFVTSKIWCSDLHAGRVVPAARETLRNLGMDYVDLLLVHWPVSLTPG 126 >UniRef50_Q5KI95 Cluster: Aldo-keto reductase, putative; n=14; Dikarya|Rep: Aldo-keto reductase, putative - Cryptococcus neoformans (Filobasidiella neoformans) Length = 353 Score = 89.8 bits (213), Expect = 8e-17 Identities = 45/115 (39%), Positives = 61/115 (53%), Gaps = 3/115 (2%) Frame = +1 Query: 436 NLNFQYLDLYLIHWPQAYKEDGS--LFPTDQSGKIQFS-DVDYVDTWKAMEPLVKEGLVK 606 +L YLDLYLIHWP +G+ LFP G D D TW ME ++K+G K Sbjct: 127 SLQTDYLDLYLIHWPVRLAPNGTHPLFPVKPDGSRNLDWDWDQAKTWAQMEDVLKKGKAK 186 Query: 607 SIGVSNFNSKQLERLLXHAXVKPVVNXVECHPYLNXKRLKEFCXXRGVXIXXYSP 771 +IG+SN +E ++ V P VN VE HPY L ++C +G+ + YSP Sbjct: 187 AIGLSNAGIPIIEHIIKTGKVTPAVNQVELHPYCPQHALLKYCKEKGILLEAYSP 241 Score = 81.8 bits (193), Expect = 2e-14 Identities = 43/92 (46%), Positives = 56/92 (60%) Frame = +3 Query: 180 PXFGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIKEGVVTREDL 359 P GLGTW++K GEV QAV A+ GYRHID A Y NE EVG IK+ V R ++ Sbjct: 48 PAIGLGTWQAKAGEVRQAVAHALKAGYRHIDGALCYQNEDEVGLG----IKDSGVPRSEI 103 Query: 360 FITSKLWNTFHRPDLVRGALQETLEQSELSVL 455 F+TSK+W+++H D V L TL+ + L Sbjct: 104 FLTSKVWSSYH--DRVEECLDTTLKSLQTDYL 133 >UniRef50_Q7G765 Cluster: Probable NAD(P)H-dependent oxidoreductase 2; n=6; Magnoliophyta|Rep: Probable NAD(P)H-dependent oxidoreductase 2 - Oryza sativa subsp. japonica (Rice) Length = 322 Score = 89.4 bits (212), Expect = 1e-16 Identities = 45/117 (38%), Positives = 63/117 (53%) Frame = +1 Query: 421 RRPWNNLNFQYLDLYLIHWPQAYKEDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGL 600 R NL Y+DL L+HWP FP + D++ V W+ ME + GL Sbjct: 103 RETLRNLGMDYVDLLLVHWPATVAPGSYDFPFPKEEMAPAFDMEGV--WRGMEECHRLGL 160 Query: 601 VKSIGVSNFNSKQLERLLXHAXVKPVVNXVECHPYLNXKRLKEFCXXRGVXIXXYSP 771 ++IGVSNF++K+LE+LL A V+P N VE +P + L+E C GV + YSP Sbjct: 161 ARAIGVSNFSAKKLEQLLSFAVVRPAANQVEMNPMWQQRTLREVCRREGVQLCGYSP 217 Score = 64.1 bits (149), Expect = 5e-09 Identities = 42/117 (35%), Positives = 61/117 (52%), Gaps = 8/117 (6%) Frame = +3 Query: 159 STMEXLFPXFGLGTWK---SKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKI 329 S + P G+GT + E T A+ AI++GYRH D A +Y E V EA+ + Sbjct: 12 SALLPTMPRIGMGTAAFPFTSSEETTAALLRAIELGYRHFDTARLYATEGCVSEAVAEAV 71 Query: 330 KEGVV-TREDLFITSKLWNTFHRPDLVRGALQETLEQSELS----VLGSVPDTLAPG 485 + G+V +R D+F+TSKLW + V A +ETL + +L P T+APG Sbjct: 72 RRGLVASRADVFVTSKLWCSDLHAGRVVPAARETLRNLGMDYVDLLLVHWPATVAPG 128 >UniRef50_P23901 Cluster: Aldose reductase; n=9; Poaceae|Rep: Aldose reductase - Hordeum vulgare (Barley) Length = 320 Score = 89.4 bits (212), Expect = 1e-16 Identities = 46/112 (41%), Positives = 61/112 (54%) Frame = +1 Query: 436 NLNFQYLDLYLIHWPQAYKEDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIG 615 +L Y+DLY IHWP K DG+ P + ++F D WK ME LVK+GLVK IG Sbjct: 109 DLQLDYIDLYHIHWPFRLK-DGAHMPPEAGEVLEF---DMEGVWKEMENLVKDGLVKDIG 164 Query: 616 VSNFNSKQLERLLXHAXVKPVVNXVECHPYLNXKRLKEFCXXRGVXIXXYSP 771 V N+ +L RLL A + P V +E HP ++ E C G+ + YSP Sbjct: 165 VCNYTVTKLNRLLRSAKIPPAVCQMEMHPGWKNDKIFEACKKHGIHVTAYSP 216 Score = 79.8 bits (188), Expect = 9e-14 Identities = 40/93 (43%), Positives = 61/93 (65%), Gaps = 1/93 (1%) Frame = +3 Query: 180 PXFGLGTWKSKPGEVTQAVKDAI-DIGYRHIDCAYVYGNEKEVGEAITSKIKEGVVTRED 356 P GLGTW++ + +V+ AI + GYRH+D A YG EKEVG+ + + ++ G + R+D Sbjct: 25 PAVGLGTWRAG-SDTAHSVRTAITEAGYRHVDTAAEYGVEKEVGKGLKAAMEAG-IDRKD 82 Query: 357 LFITSKLWNTFHRPDLVRGALQETLEQSELSVL 455 LF+TSK+W T P+ VR AL+ TL+ +L + Sbjct: 83 LFVTSKIWCTNLAPERVRPALENTLKDLQLDYI 115 >UniRef50_Q41399 Cluster: Chalcone reductase; n=4; eudicotyledons|Rep: Chalcone reductase - Sesbania rostrata Length = 322 Score = 89.0 bits (211), Expect = 1e-16 Identities = 45/111 (40%), Positives = 61/111 (54%) Frame = +1 Query: 439 LNFQYLDLYLIHWPQAYKEDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGV 618 L +Y+DLYLIHWP + D L K D TWKAME + GL KSIG+ Sbjct: 108 LGMEYVDLYLIHWPVRLRHD--LENPVIFSKEDLLPFDIEGTWKAMEECYRLGLAKSIGI 165 Query: 619 SNFNSKQLERLLXHAXVKPVVNXVECHPYLNXKRLKEFCXXRGVXIXXYSP 771 N+ +K+L +LL A + P VN VE +P L+EFC +G+ + +SP Sbjct: 166 CNYGTKKLTKLLEIATIPPAVNQVEMNPSWQQGNLREFCKQKGIHVSAWSP 216 Score = 74.5 bits (175), Expect = 3e-12 Identities = 38/90 (42%), Positives = 59/90 (65%), Gaps = 4/90 (4%) Frame = +3 Query: 180 PXFGLGTW-KSKPGE--VTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIKEGVV-T 347 P G+GT +S+P + DAI +GYRH D A VYG E+ +G A++ I++G++ + Sbjct: 18 PVIGMGTSVESRPSNDVLASIFVDAIQVGYRHFDSASVYGTEEAIGMAVSKAIEQGLIKS 77 Query: 348 REDLFITSKLWNTFHRPDLVRGALQETLEQ 437 R+++FITSK WNT DL+ AL+ TL++ Sbjct: 78 RDEVFITSKPWNTDAHHDLIVPALKTTLKK 107 >UniRef50_Q6RZX1 Cluster: Gld1; n=22; Pezizomycotina|Rep: Gld1 - Trichoderma atroviride (Hypocrea atroviridis) Length = 327 Score = 89.0 bits (211), Expect = 1e-16 Identities = 46/116 (39%), Positives = 64/116 (55%), Gaps = 4/116 (3%) Frame = +1 Query: 436 NLNFQYLDLYLIHWPQAYKEDGS-LFPTDQSGKIQFSDV---DYVDTWKAMEPLVKEGLV 603 NL Y+DL+L+HWP A +++ GK + + TW+AME LV G+V Sbjct: 112 NLKVDYIDLFLVHWPIAAEKNADRTVKIGPDGKYVINKALTENPEPTWRAMEELVDSGIV 171 Query: 604 KSIGVSNFNSKQLERLLXHAXVKPVVNXVECHPYLNXKRLKEFCXXRGVXIXXYSP 771 K+IGVSN+ L++LL A +KP VN +E HP+L L EFC + YSP Sbjct: 172 KAIGVSNWTIPGLKQLLEFARIKPAVNQIEIHPFLPNTELVEFCFQNDILPEAYSP 227 Score = 80.2 bits (189), Expect = 6e-14 Identities = 39/95 (41%), Positives = 60/95 (63%), Gaps = 3/95 (3%) Frame = +3 Query: 180 PXFGLGTWKSK--PGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKI-KEGVVTR 350 P G GT+ ++ GE AV A+D+GYRH+DCA+ Y NE EVG+AI + + VTR Sbjct: 24 PAVGFGTFANEGAKGETYAAVTKALDVGYRHLDCAWFYLNEDEVGDAIRDFLARRPDVTR 83 Query: 351 EDLFITSKLWNTFHRPDLVRGALQETLEQSELSVL 455 +DLFI +K+WN H P+ V+ + + + E ++ + Sbjct: 84 KDLFICTKVWNHLHEPEDVKWSAKNSCENLKVDYI 118 >UniRef50_Q4PAT5 Cluster: Putative uncharacterized protein; n=1; Ustilago maydis|Rep: Putative uncharacterized protein - Ustilago maydis (Smut fungus) Length = 700 Score = 89.0 bits (211), Expect = 1e-16 Identities = 45/118 (38%), Positives = 74/118 (62%), Gaps = 6/118 (5%) Frame = +1 Query: 436 NLNFQYLDLYLIHWPQAY-KEDGSLFPTDQSG---KIQFSDV--DYVDTWKAMEPLVKEG 597 +L YLDLYL+HWP A+ GS+ P+ +S ++ D+ D++ T++ ME +VK+G Sbjct: 102 DLGTDYLDLYLMHWPVAFLNSKGSMVPSIRSTGGHPVESEDLSRDFMATYRVMEEMVKKG 161 Query: 598 LVKSIGVSNFNSKQLERLLXHAXVKPVVNXVECHPYLNXKRLKEFCXXRGVXIXXYSP 771 V++IGVSNFN ++ ++ A +KPVVN VE + ++ + L+ + GV + YSP Sbjct: 162 KVRNIGVSNFNIRRTSEVVDEASIKPVVNQVEVNLGVHNEELRNYAHAHGVTLQAYSP 219 Score = 86.2 bits (204), Expect = 1e-15 Identities = 41/85 (48%), Positives = 53/85 (62%) Frame = +3 Query: 180 PXFGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIKEGVVTREDL 359 P G GTWK + T AV AI GYRHIDCA+ Y NE +A+ + IK+ V R L Sbjct: 21 PKLGFGTWKMSKEQATPAVAHAIKTGYRHIDCAWAYRNE----DAVAAGIKKAGVPRSQL 76 Query: 360 FITSKLWNTFHRPDLVRGALQETLE 434 ++TSKLWN+FH P+ V AL +L+ Sbjct: 77 WLTSKLWNSFHHPEHVEKALDASLK 101 >UniRef50_Q1IN88 Cluster: Aldehyde reductase; n=5; Bacteria|Rep: Aldehyde reductase - Acidobacteria bacterium (strain Ellin345) Length = 313 Score = 88.6 bits (210), Expect = 2e-16 Identities = 43/114 (37%), Positives = 64/114 (56%), Gaps = 1/114 (0%) Frame = +1 Query: 433 NNLNFQYLDLYLIHWPQAYKEDGSLFPTDQSGKIQFSD-VDYVDTWKAMEPLVKEGLVKS 609 + L YLDLYLIH P A++ P DQ+G + + + V +TW A+E LV G ++ Sbjct: 105 DRLGLDYLDLYLIHTPFAFQPGDEQDPRDQNGSVIYDEGVTLRETWSALENLVDRGRCRA 164 Query: 610 IGVSNFNSKQLERLLXHAXVKPVVNXVECHPYLNXKRLKEFCXXRGVXIXXYSP 771 IG+S+ + +L + A +KP V VE HPYL L EFC G+ + ++P Sbjct: 165 IGLSDISMDRLAPIYEAARIKPAVVQVESHPYLPETELLEFCKRNGIVLLAFAP 218 Score = 88.2 bits (209), Expect = 2e-16 Identities = 40/92 (43%), Positives = 57/92 (61%) Frame = +3 Query: 180 PXFGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIKEGVVTREDL 359 P G GT + P A +DA+ G+RH DCA Y NE+EVGEA+ + G + RE++ Sbjct: 21 PALGFGTLIADPALTITATRDALAAGFRHFDCAERYRNEREVGEALRAGRAAGNIAREEI 80 Query: 360 FITSKLWNTFHRPDLVRGALQETLEQSELSVL 455 F+T+KLWNT HRP+ V A + +L++ L L Sbjct: 81 FVTTKLWNTNHRPERVEPAFEASLDRLGLDYL 112 >UniRef50_A1D4E3 Cluster: D-xylose reductase (Xyl1), putative; n=5; Pezizomycotina|Rep: D-xylose reductase (Xyl1), putative - Neosartorya fischeri (strain ATCC 1020 / DSM 3700 / NRRL 181)(Aspergillus fischerianus (strain ATCC 1020 / DSM 3700 / NRRL 181)) Length = 321 Score = 88.6 bits (210), Expect = 2e-16 Identities = 43/122 (35%), Positives = 70/122 (57%), Gaps = 5/122 (4%) Frame = +1 Query: 418 CRRPWNNLNFQYLDLYLIHWPQA--YKEDGSLFPT---DQSGKIQFSDVDYVDTWKAMEP 582 CR+ + Y DL+++H+P A Y + +P ++ K++FS+ +TW AME Sbjct: 94 CRKQLADWGLDYFDLFIVHFPIALKYVDPAVRYPPGWLSENNKLEFSNASIQETWTAMES 153 Query: 583 LVKEGLVKSIGVSNFNSKQLERLLXHAXVKPVVNXVECHPYLNXKRLKEFCXXRGVXIXX 762 LV + L +SIGVSNF+++ L LL +A ++P +E HPYL +RL + G+ + Sbjct: 154 LVDKKLARSIGVSNFSAQLLMDLLRYARIRPATLQIEHHPYLTQERLVTYAQKEGIAVTA 213 Query: 763 YS 768 YS Sbjct: 214 YS 215 Score = 77.8 bits (183), Expect = 3e-13 Identities = 38/84 (45%), Positives = 46/84 (54%) Frame = +3 Query: 180 PXFGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIKEGVVTREDL 359 P G G WK + AI GYR D A YGNE E G+ + I+EG+V REDL Sbjct: 15 PLVGFGLWKVNNETCADQIYHAIKAGYRLFDGACDYGNEVEAGKGVARAIQEGIVKREDL 74 Query: 360 FITSKLWNTFHRPDLVRGALQETL 431 FI SKLWN+FH D V ++ L Sbjct: 75 FIVSKLWNSFHDGDRVEPICRKQL 98 >UniRef50_Q1U9L6 Cluster: 2,5-didehydrogluconate reductase; n=3; Lactobacillus|Rep: 2,5-didehydrogluconate reductase - Lactobacillus reuteri 100-23 Length = 288 Score = 88.2 bits (209), Expect = 2e-16 Identities = 44/92 (47%), Positives = 60/92 (65%) Frame = +3 Query: 180 PXFGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIKEGVVTREDL 359 P G GT+++ QAVK+AI+ GYRHID A VYGNE+ VG+ IK+ + REDL Sbjct: 20 PCVGYGTFRTPADVAEQAVKEAIETGYRHIDTAAVYGNEEAVGKG----IKDSGIKREDL 75 Query: 360 FITSKLWNTFHRPDLVRGALQETLEQSELSVL 455 F+TSKLWNT + + A QETL++ ++ L Sbjct: 76 FVTSKLWNTNRGYEQTKKAFQETLDRLQMDYL 107 Score = 73.3 bits (172), Expect = 7e-12 Identities = 39/113 (34%), Positives = 58/113 (51%) Frame = +1 Query: 433 NNLNFQYLDLYLIHWPQAYKEDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSI 612 + L YLDLYLIHWP K+ G D + KI +TW+AME L EG +++I Sbjct: 100 DRLQMDYLDLYLIHWPANEKQFG-----DDAAKIN------AETWRAMEDLYNEGKIRAI 148 Query: 613 GVSNFNSKQLERLLXHAXVKPVVNXVECHPYLNXKRLKEFCXXRGVXIXXYSP 771 GVSNF + L+ A V P V+ +E HP + ++ + + ++P Sbjct: 149 GVSNFMPHHIAELMKTAKVAPAVDQIEVHPGWPHTEVVKYLQAHNILVEAWAP 201 >UniRef50_Q17G72 Cluster: Aldo-keto reductase; n=9; Endopterygota|Rep: Aldo-keto reductase - Aedes aegypti (Yellowfever mosquito) Length = 316 Score = 88.2 bits (209), Expect = 2e-16 Identities = 40/113 (35%), Positives = 64/113 (56%) Frame = +1 Query: 433 NNLNFQYLDLYLIHWPQAYKEDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSI 612 ++L +Y+DLY +H P E F + + + D+V WKAME + + GL ++I Sbjct: 100 DDLQLEYVDLYHVHVPFTVPEVDGPFLVEDGLIVLETTTDHVALWKAMEEVYEAGLARNI 159 Query: 613 GVSNFNSKQLERLLXHAXVKPVVNXVECHPYLNXKRLKEFCXXRGVXIXXYSP 771 G+SNFN +Q++R+L + +KP +E H YL L +FC G+ + YSP Sbjct: 160 GLSNFNQRQIQRILDNCQIKPANLQIENHIYLQQPELVKFCKANGITVTAYSP 212 Score = 74.1 bits (174), Expect = 4e-12 Identities = 36/89 (40%), Positives = 54/89 (60%) Frame = +3 Query: 180 PXFGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIKEGVVTREDL 359 P G GTW++ EV +A+ +A++ GYRHID A VY NEK +G+ + + G VTR++L Sbjct: 16 PALGFGTWRASDEEVEKALNEALEAGYRHIDTAPVYLNEKTIGKVLKEWMDAGKVTRDEL 75 Query: 360 FITSKLWNTFHRPDLVRGALQETLEQSEL 446 FI +KL R V L+ +L+ +L Sbjct: 76 FIVTKLPPHGTRASTVEKFLKNSLDDLQL 104 >UniRef50_A5E082 Cluster: GCY protein; n=4; Saccharomycetales|Rep: GCY protein - Lodderomyces elongisporus (Yeast) (Saccharomyces elongisporus) Length = 295 Score = 88.2 bits (209), Expect = 2e-16 Identities = 46/114 (40%), Positives = 66/114 (57%), Gaps = 3/114 (2%) Frame = +1 Query: 439 LNFQYLDLYLIHWPQAYKEDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGL-VKSIG 615 L +Y+DLYLIHWP + D + + D D+VDTW+ ++ + KEG VK+IG Sbjct: 102 LGLEYVDLYLIHWPLS---------VDPKTEKPYDDYDFVDTWRNLQKIYKEGKKVKAIG 152 Query: 616 VSNFNSKQLERLLXHAXVK--PVVNXVECHPYLNXKRLKEFCXXRGVXIXXYSP 771 VSNFN K+L++LL V PV+N +E HP L L ++ + + I YSP Sbjct: 153 VSNFNKKKLDKLLNSEGVNVVPVINQIEAHPLLTQPDLFDYLKSKDIYITAYSP 206 Score = 68.9 bits (161), Expect = 2e-10 Identities = 36/87 (41%), Positives = 53/87 (60%), Gaps = 1/87 (1%) Frame = +3 Query: 180 PXFGLGTWKSKPGEVT-QAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIKEGVVTRED 356 P GLGTW + + +A A+ GY+HID A YGNE +VG AI + V+R++ Sbjct: 21 PAIGLGTWLADEEDAAYKATLTALKNGYKHIDTAAAYGNEDQVGRAIA----DSGVSRDE 76 Query: 357 LFITSKLWNTFHRPDLVRGALQETLEQ 437 +F+T+KLWN H+ GAL E+L++ Sbjct: 77 IFVTTKLWNDQHKDP--EGALDESLKK 101 >UniRef50_Q6CFG7 Cluster: Yarrowia lipolytica chromosome B of strain CLIB122 of Yarrowia lipolytica; n=9; Ascomycota|Rep: Yarrowia lipolytica chromosome B of strain CLIB122 of Yarrowia lipolytica - Yarrowia lipolytica (Candida lipolytica) Length = 337 Score = 87.4 bits (207), Expect = 4e-16 Identities = 46/114 (40%), Positives = 59/114 (51%), Gaps = 3/114 (2%) Frame = +1 Query: 439 LNFQYLDLYLIHWPQAYKEDGS--LFPTDQSGKIQFSDV-DYVDTWKAMEPLVKEGLVKS 609 L Y+D+ LIHWP +G+ ++P G + TWK ME ++K G KS Sbjct: 127 LGLDYVDMLLIHWPVPLNPNGNDPVYPLRPDGSRDIDESGSQPKTWKQMEAVLKTGKTKS 186 Query: 610 IGVSNFNSKQLERLLXHAXVKPVVNXVECHPYLNXKRLKEFCXXRGVXIXXYSP 771 IGVSNF+ LE LL A V P VN VE HP L L EFC + + +SP Sbjct: 187 IGVSNFSIPYLEELLKEAEVVPAVNQVELHPLLPQLELMEFCKKNNIVMTAFSP 240 Score = 76.2 bits (179), Expect = 1e-12 Identities = 42/87 (48%), Positives = 56/87 (64%), Gaps = 1/87 (1%) Frame = +3 Query: 180 PXFGLGTWKSKPGEVTQAVKDAI-DIGYRHIDCAYVYGNEKEVGEAITSKIKEGVVTRED 356 P GLGTWKS EV AV+ A+ + GYRHID A+ Y NE VG I +++G V RED Sbjct: 43 PAIGLGTWKSTTEEVAGAVECALTEGGYRHIDTAFNYRNEDAVGLGIKRAMEKG-VKRED 101 Query: 357 LFITSKLWNTFHRPDLVRGALQETLEQ 437 +F+T+K+W T+H D V L +LE+ Sbjct: 102 IFVTTKIWVTYH--DRVEENLDMSLER 126 >UniRef50_Q9FJK0 Cluster: Aldose reductase-like protein; n=3; core eudicotyledons|Rep: Aldose reductase-like protein - Arabidopsis thaliana (Mouse-ear cress) Length = 316 Score = 87.0 bits (206), Expect = 6e-16 Identities = 43/111 (38%), Positives = 63/111 (56%) Frame = +1 Query: 439 LNFQYLDLYLIHWPQAYKEDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGV 618 + YLD YL+HWP K G P + + + D+ +TW+ ME ++ GL +SIGV Sbjct: 101 MGLDYLDNYLVHWPIKLKP-GVSEPIPKEDEFE-KDLGIEETWQGMERCLEMGLCRSIGV 158 Query: 619 SNFNSKQLERLLXHAXVKPVVNXVECHPYLNXKRLKEFCXXRGVXIXXYSP 771 SNF+SK++ LL A V P VN VE HP ++L++ C + + YSP Sbjct: 159 SNFSSKKIFDLLDFASVSPSVNQVEMHPLWRQRKLRKVCEENNIHVSGYSP 209 Score = 75.8 bits (178), Expect = 1e-12 Identities = 46/109 (42%), Positives = 62/109 (56%), Gaps = 6/109 (5%) Frame = +3 Query: 180 PXFGLGTW-KSKPGEVT-QAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIKEGVVTRE 353 P G+GT+ K E T AV AI IGYRH D A +YG+E+ +G A+ I G V R+ Sbjct: 15 PLLGMGTYCPQKDRESTISAVHQAIKIGYRHFDTAKIYGSEEALGTALGQAISYGTVQRD 74 Query: 354 DLFITSKLWNTFHRPDLVRGALQETLEQSELSVLGSV----PDTLAPGL 488 DLF+TSKLW++ H + AL +TL+ L L + P L PG+ Sbjct: 75 DLFVTSKLWSSDHHDPI--SALIQTLKTMGLDYLDNYLVHWPIKLKPGV 121 >UniRef50_UPI000023D0F1 Cluster: hypothetical protein FG03517.1; n=1; Gibberella zeae PH-1|Rep: hypothetical protein FG03517.1 - Gibberella zeae PH-1 Length = 364 Score = 86.6 bits (205), Expect = 7e-16 Identities = 41/84 (48%), Positives = 58/84 (69%) Frame = +3 Query: 180 PXFGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIKEGVVTREDL 359 P FGLGTW + G V AV+ A+ GYRHID A ++ NE EVG+ IK V+R+++ Sbjct: 61 PAFGLGTWLAGKGVVVPAVEYALKGGYRHIDTALIWRNEDEVGKG----IKASGVSRDEI 116 Query: 360 FITSKLWNTFHRPDLVRGALQETL 431 ++T KLWNT HRP+LVR A++ ++ Sbjct: 117 WVTGKLWNTDHRPELVRKAIETSI 140 Score = 79.4 bits (187), Expect = 1e-13 Identities = 40/112 (35%), Positives = 62/112 (55%) Frame = +1 Query: 436 NLNFQYLDLYLIHWPQAYKEDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIG 615 NL +YLDLYLIH+P A+ ++ + ++ +DTWKAME LV+ GL ++IG Sbjct: 142 NLGVEYLDLYLIHYPVAW--------VPETRDVD-NNTSLIDTWKAMEELVRAGLTRNIG 192 Query: 616 VSNFNSKQLERLLXHAXVKPVVNXVECHPYLNXKRLKEFCXXRGVXIXXYSP 771 SNF K + ++L A ++P + E HPYL + +F + + SP Sbjct: 193 FSNFAPKDINKILKIASIQPYAHEFETHPYLQQQSFVDFHKKENIKVIAASP 244 >UniRef50_P38115 Cluster: D-arabinose dehydrogenase [NAD(P)+] heavy chain; n=3; Saccharomycetaceae|Rep: D-arabinose dehydrogenase [NAD(P)+] heavy chain - Saccharomyces cerevisiae (Baker's yeast) Length = 344 Score = 86.6 bits (205), Expect = 7e-16 Identities = 47/123 (38%), Positives = 71/123 (57%), Gaps = 12/123 (9%) Frame = +1 Query: 439 LNFQYLDLYLIHWPQAYKE-------DGSL-FPTDQSGKIQFS-DVDYVDTWKAMEPLV- 588 L +Y+DL L HWP +++ G + P D SGK ++ D DY++T+K +E + Sbjct: 120 LGLEYVDLLLQHWPLCFEKIKDPKGISGLVKTPVDDSGKTMYAADGDYLETYKQLEKIYL 179 Query: 589 --KEGLVKSIGVSNFNSKQLERLLXHAXVKPVVNXVECHPYLNXKRLKEFCXXRGVXIXX 762 + V++IGVSNF+ + LERL+ VKP VN VE HP+L L++FC + + Sbjct: 180 DPNDHRVRAIGVSNFSIEYLERLIKECRVKPTVNQVETHPHLPQMELRKFCFMHDILLTA 239 Query: 763 YSP 771 YSP Sbjct: 240 YSP 242 Score = 73.3 bits (172), Expect = 7e-12 Identities = 42/87 (48%), Positives = 52/87 (59%), Gaps = 2/87 (2%) Frame = +3 Query: 180 PXFGLGTWK--SKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIKEGVVTRE 353 P GLGT K E QAVK AI GYRHID A+ Y E VGEAI +++G + RE Sbjct: 34 PALGLGTANPHEKLAETKQAVKAAIKAGYRHIDTAWAYETEPFVGEAIKELLEDGSIKRE 93 Query: 354 DLFITSKLWNTFHRPDLVRGALQETLE 434 DLFIT+K+W D V +L E+L+ Sbjct: 94 DLFITTKVWPVLW--DEVDRSLNESLK 118 >UniRef50_UPI00015B5BD7 Cluster: PREDICTED: similar to aldo-keto reductase; n=1; Nasonia vitripennis|Rep: PREDICTED: similar to aldo-keto reductase - Nasonia vitripennis Length = 310 Score = 86.2 bits (204), Expect = 1e-15 Identities = 48/111 (43%), Positives = 65/111 (58%), Gaps = 1/111 (0%) Frame = +1 Query: 439 LNFQYLDLYLIHWPQAYKEDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGV 618 L+ YLDLYLIHWP A + L + + K++ V TW + L ++GL++SIGV Sbjct: 123 LDTSYLDLYLIHWPGASR---ILENSPDNPKLR------VTTWATLVELQQKGLLRSIGV 173 Query: 619 SNFNSKQLERLLXH-AXVKPVVNXVECHPYLNXKRLKEFCXXRGVXIXXYS 768 SN+ LE LL H + VKP VN VECHP+ L EFC +G+ + YS Sbjct: 174 SNYTVGHLEHLLEHCSGVKPDVNQVECHPHFRQDELIEFCTKQGIHVQAYS 224 Score = 63.3 bits (147), Expect = 8e-09 Identities = 35/94 (37%), Positives = 60/94 (63%), Gaps = 2/94 (2%) Frame = +3 Query: 180 PXFGLGTWKSKPGEVTQAVKD-AIDIGYRHIDCAYVYGNEKEVGEAITSKIKEGVVTRED 356 P G+GT+K + EV + V D + +G+R ID A VY NE+++G A+ + + + RED Sbjct: 35 PLVGIGTYKVRGREVIKRVIDESFAVGFRSIDTAVVYRNEEDIGLALKELLPKYNLKRED 94 Query: 357 LFITSKLWNTFH-RPDLVRGALQETLEQSELSVL 455 +FITSKL + + PD +R +++++L+ + S L Sbjct: 95 IFITSKLSPSDNGDPDKIRKSVEDSLKALDTSYL 128 >UniRef50_A6W8E7 Cluster: 2,5-didehydrogluconate reductase; n=3; Actinomycetales|Rep: 2,5-didehydrogluconate reductase - Kineococcus radiotolerans SRS30216 Length = 289 Score = 86.2 bits (204), Expect = 1e-15 Identities = 39/86 (45%), Positives = 58/86 (67%) Frame = +3 Query: 180 PXFGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIKEGVVTREDL 359 P G G ++ +PG+ QAVK A+D+GYRHID A +YGNE EV + I + V R+++ Sbjct: 24 PQLGFGVFQIEPGDTAQAVKTALDLGYRHIDTAQMYGNEAEVAQGIA----DSGVPRDEI 79 Query: 360 FITSKLWNTFHRPDLVRGALQETLEQ 437 ++TSKL N FH PD R A+ +++E+ Sbjct: 80 WVTSKLNNGFHEPDAARKAVDDSVEK 105 Score = 74.5 bits (175), Expect = 3e-12 Identities = 40/106 (37%), Positives = 53/106 (50%) Frame = +1 Query: 454 LDLYLIHWPQAYKEDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNS 633 +DLYLIHWP PT G D+V TWK +E G ++SIGVSNF Sbjct: 110 IDLYLIHWP---------LPTLYGG-------DFVSTWKVLEEARAAGKLRSIGVSNFQV 153 Query: 634 KQLERLLXHAXVKPVVNXVECHPYLNXKRLKEFCXXRGVXIXXYSP 771 L+RL A V P VN +E HPY + ++ C + + +SP Sbjct: 154 NHLQRLAQEATVVPAVNQIEVHPYFGNEEVRRHCGEHQIGVEAWSP 199 >UniRef50_Q8J0K1 Cluster: 4-dihydromethyltrisporate dehydrogenase; n=2; Parasitella parasitica|Rep: 4-dihydromethyltrisporate dehydrogenase - Parasitella parasitica Length = 321 Score = 86.2 bits (204), Expect = 1e-15 Identities = 43/89 (48%), Positives = 50/89 (56%) Frame = +3 Query: 168 EXLFPXFGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIKEGVVT 347 E P G G WK + + + AI IGYR D A YGNE EVG I IKEG+V Sbjct: 12 EDKMPLRGFGCWKIEKKDAENTIYQAIKIGYRLFDGACDYGNEVEVGRGINKAIKEGLVK 71 Query: 348 REDLFITSKLWNTFHRPDLVRGALQETLE 434 RE+LFI +KLWNTFH VR A L+ Sbjct: 72 REELFIVTKLWNTFHSKQHVRTAFDRQLK 100 Score = 73.7 bits (173), Expect = 6e-12 Identities = 40/121 (33%), Positives = 64/121 (52%), Gaps = 6/121 (4%) Frame = +1 Query: 424 RPWNNLNFQYLDLYLIHWP--QAYKEDGSLFPTD----QSGKIQFSDVDYVDTWKAMEPL 585 R + +Y DLYLIH+P Y + +P + + K+ F + W ME L Sbjct: 97 RQLKDWGLEYFDLYLIHFPIPLQYVDPAVSYPPEWYVPHADKLNFERSPIHECWAEMEKL 156 Query: 586 VKEGLVKSIGVSNFNSKQLERLLXHAXVKPVVNXVECHPYLNXKRLKEFCXXRGVXIXXY 765 V+ L ++IGV+NFN + + LL +A +KP V +E HP L +RL ++ +G+ + Y Sbjct: 157 VQAKLTRNIGVANFNCQAILDLLSYAKIKPAVLQIEIHPLLPQERLVKWVQEQGIQVTAY 216 Query: 766 S 768 S Sbjct: 217 S 217 >UniRef50_A6RKL9 Cluster: Putative uncharacterized protein; n=3; Sclerotiniaceae|Rep: Putative uncharacterized protein - Botryotinia fuckeliana B05.10 Length = 360 Score = 85.8 bits (203), Expect = 1e-15 Identities = 45/95 (47%), Positives = 55/95 (57%), Gaps = 3/95 (3%) Frame = +3 Query: 180 PXFGLGTWKSK--PGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIKEGVVTRE 353 P G GTW K P T+AV AI+IGYR IDCA VYGNE VG I +K + RE Sbjct: 40 PLIGFGTWNLKVSPENTTEAVAYAIEIGYRQIDCAAVYGNEVAVGRGIEEGLKRAGLKRE 99 Query: 354 DLFITSKLWNTFHRP-DLVRGALQETLEQSELSVL 455 D+++TSKLWN H + V L +TL+ L L Sbjct: 100 DIWVTSKLWNDHHGSYENVEKGLNQTLQDLGLEYL 134 Score = 62.1 bits (144), Expect = 2e-08 Identities = 38/112 (33%), Positives = 59/112 (52%) Frame = +1 Query: 436 NLNFQYLDLYLIHWPQAYKEDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIG 615 +L +YLDLYLIHWP + +G+ ++D+V T+K+M L K V +IG Sbjct: 128 DLGLEYLDLYLIHWPIGFSSNGA------------KNLDHVQTYKSMISLPK-SRVLNIG 174 Query: 616 VSNFNSKQLERLLXHAXVKPVVNXVECHPYLNXKRLKEFCXXRGVXIXXYSP 771 VSNF+ QL+ ++ + P ++ +E HPYL G+ + YSP Sbjct: 175 VSNFSPLQLKNVVSTGTI-PYMHQMELHPYLQQSAWVATHKALGIKMTAYSP 225 >UniRef50_A6ESC0 Cluster: ARA1; n=1; unidentified eubacterium SCB49|Rep: ARA1 - unidentified eubacterium SCB49 Length = 280 Score = 85.0 bits (201), Expect = 2e-15 Identities = 46/113 (40%), Positives = 63/113 (55%) Frame = +1 Query: 433 NNLNFQYLDLYLIHWPQAYKEDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSI 612 N+L YLDLYLIHWP A + ++ K Q ++ DTW AME L K+G +K++ Sbjct: 95 NDLQLDYLDLYLIHWPAAAHQF-------ENWK-QLNN----DTWSAMEKLYKDGKIKAL 142 Query: 613 GVSNFNSKQLERLLXHAXVKPVVNXVECHPYLNXKRLKEFCXXRGVXIXXYSP 771 GVSNF L LL HA +KP VN +E HP + +FC + + +SP Sbjct: 143 GVSNFMEHHLTPLLQHATIKPTVNQIEYHPGYMQQDCVQFCNDNNIQVEGWSP 195 Score = 74.9 bits (176), Expect = 2e-12 Identities = 39/93 (41%), Positives = 52/93 (55%), Gaps = 1/93 (1%) Frame = +3 Query: 180 PXFGLGTWKSKPGEVT-QAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIKEGVVTRED 356 P G GTW++ G+ A+K AID GY+HID A +Y NEK VG IKE + R+D Sbjct: 14 PAIGFGTWQTPDGQTAINAIKTAIDAGYKHIDAAAIYKNEKGVGLG----IKEANIDRKD 69 Query: 357 LFITSKLWNTFHRPDLVRGALQETLEQSELSVL 455 LF+TSK+WN + A T+ +L L Sbjct: 70 LFVTSKVWNEQRGYENTLKAFDNTINDLQLDYL 102 >UniRef50_Q3E9M9 Cluster: Uncharacterized protein At5g01670.2; n=7; Magnoliophyta|Rep: Uncharacterized protein At5g01670.2 - Arabidopsis thaliana (Mouse-ear cress) Length = 349 Score = 85.0 bits (201), Expect = 2e-15 Identities = 45/111 (40%), Positives = 61/111 (54%) Frame = +1 Query: 439 LNFQYLDLYLIHWPQAYKEDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGV 618 L +YLDLYLIHWP +E S P ++G + D D W+ ME L K+ LV++IGV Sbjct: 137 LQLEYLDLYLIHWPIRLREGASKPP--KAGDVL--DFDMEGVWREMENLSKDSLVRNIGV 192 Query: 619 SNFNSKQLERLLXHAXVKPVVNXVECHPYLNXKRLKEFCXXRGVXIXXYSP 771 NF +L +LL A + P V +E HP R+ EFC + + YSP Sbjct: 193 CNFTVTKLNKLLGFAELIPAVCQMEMHPGWRNDRILEFCKKNEIHVTAYSP 243 Score = 68.5 bits (160), Expect = 2e-10 Identities = 32/69 (46%), Positives = 43/69 (62%) Frame = +3 Query: 180 PXFGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIKEGVVTREDL 359 P GLGTW+S V ++ GYRHID A+ YG+++EVG+ I + G + R DL Sbjct: 25 PAVGLGTWRSGSQAAHAVVTAIVEGGYRHIDTAWEYGDQREVGQGIKRAMHAG-LERRDL 83 Query: 360 FITSKLWNT 386 F+TSKLW T Sbjct: 84 FVTSKLWYT 92 >UniRef50_P28475 Cluster: NADP-dependent D-sorbitol-6-phosphate dehydrogenase; n=71; Magnoliophyta|Rep: NADP-dependent D-sorbitol-6-phosphate dehydrogenase - Malus domestica (Apple) (Malus sylvestris) Length = 310 Score = 85.0 bits (201), Expect = 2e-15 Identities = 40/92 (43%), Positives = 59/92 (64%) Frame = +3 Query: 180 PXFGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIKEGVVTREDL 359 P GLG W+ + E+ + + +AI IGYRH DCA Y +E +VGEA+ K G+V RE+L Sbjct: 13 PVIGLGLWRLEKDELKEVILNAIKIGYRHFDCAAHYKSEADVGEALAEAFKTGLVKREEL 72 Query: 360 FITSKLWNTFHRPDLVRGALQETLEQSELSVL 455 FIT+K+WN+ H V A + +LE+ ++ L Sbjct: 73 FITTKIWNSDH--GHVVEACKNSLEKLQIDYL 102 Score = 79.4 bits (187), Expect = 1e-13 Identities = 41/122 (33%), Positives = 59/122 (48%), Gaps = 4/122 (3%) Frame = +1 Query: 418 CRRPWNNLNFQYLDLYLIHWPQAYKEDGSLFPTDQSGKIQFSDVDYV----DTWKAMEPL 585 C+ L YLDLYL+H+P K + G+ + D+D TW+ ME Sbjct: 90 CKNSLEKLQIDYLDLYLVHYPMPTKHNAIGKTASLLGEDKVLDIDVTISLQQTWEGMEKT 149 Query: 586 VKEGLVKSIGVSNFNSKQLERLLXHAXVKPVVNXVECHPYLNXKRLKEFCXXRGVXIXXY 765 V GLV+SIG+SN+ L ++ +KP V+ E HPY L +FC GV + Sbjct: 150 VSLGLVRSIGLSNYELFLTRDCLAYSKIKPAVSQFETHPYFQRDSLVKFCMKHGVLPTAH 209 Query: 766 SP 771 +P Sbjct: 210 TP 211 >UniRef50_Q03PG5 Cluster: Aldo/keto reductase of diketogulonate reductase family; n=1; Lactobacillus brevis ATCC 367|Rep: Aldo/keto reductase of diketogulonate reductase family - Lactobacillus brevis (strain ATCC 367 / JCM 1170) Length = 268 Score = 84.2 bits (199), Expect = 4e-15 Identities = 42/92 (45%), Positives = 53/92 (57%) Frame = +3 Query: 180 PXFGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIKEGVVTREDL 359 P G GT+ +V A+K A+D GYRH+DCA++YGNE VGEA IK + R DL Sbjct: 13 PMLGFGTYLIDSKDVPAAIKTALDAGYRHLDCAHIYGNEPAVGEA----IKASGIDRSDL 68 Query: 360 FITSKLWNTFHRPDLVRGALQETLEQSELSVL 455 FITSK+WN D A +TL +L L Sbjct: 69 FITSKVWNADQGYDKTLAAFDQTLSDLQLDYL 100 Score = 71.7 bits (168), Expect = 2e-11 Identities = 41/113 (36%), Positives = 61/113 (53%) Frame = +1 Query: 433 NNLNFQYLDLYLIHWPQAYKEDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSI 612 ++L YLDLYLIHWP ++D L +DTW+ +E L ++ V++I Sbjct: 93 SDLQLDYLDLYLIHWPN--EDDFELT---------------LDTWRVLETLYQQKKVRAI 135 Query: 613 GVSNFNSKQLERLLXHAXVKPVVNXVECHPYLNXKRLKEFCXXRGVXIXXYSP 771 GVSNF+ QL+++ A VKP++N +E HPY L +F + YSP Sbjct: 136 GVSNFSEDQLKQVFEMATVKPMINQIERHPYKVQADLGQFDTDNDIVNEGYSP 188 >UniRef50_Q41E86 Cluster: 2,5-didehydrogluconate reductase; n=2; Bacteria|Rep: 2,5-didehydrogluconate reductase - Exiguobacterium sibiricum 255-15 Length = 274 Score = 83.8 bits (198), Expect = 5e-15 Identities = 43/111 (38%), Positives = 61/111 (54%) Frame = +1 Query: 439 LNFQYLDLYLIHWPQAYKEDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGV 618 L Y+DLYLIHWP D L Y+DTW+A+E L ++G K+IGV Sbjct: 95 LGVDYVDLYLIHWPMP---DEDL---------------YMDTWRALEQLYRDGKAKAIGV 136 Query: 619 SNFNSKQLERLLXHAXVKPVVNXVECHPYLNXKRLKEFCXXRGVXIXXYSP 771 SNF+ L R+L V P VN +E HP+L+ + ++ FC G+ + +SP Sbjct: 137 SNFHIPHLTRVLEEGTVVPAVNQIELHPFLSQEAIRAFCQKNGIVVEAWSP 187 Score = 65.7 bits (153), Expect = 1e-09 Identities = 32/88 (36%), Positives = 52/88 (59%) Frame = +3 Query: 174 LFPXFGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIKEGVVTRE 353 + P G G +K EV +AV++A+ +GYR ID A +Y NE VG A+ K+ + RE Sbjct: 11 VMPQLGYGVFKVPEQEVYEAVREALRVGYRSIDTAMIYENEAGVGRAL----KDSGIPRE 66 Query: 354 DLFITSKLWNTFHRPDLVRGALQETLEQ 437 D+F+T+K+WN + A + +L++ Sbjct: 67 DIFLTTKVWNKDQGYERTLAAFETSLQK 94 >UniRef50_Q8WRT0 Cluster: 3-dehydrecdysone 3b-reductase; n=1; Trichoplusia ni|Rep: 3-dehydrecdysone 3b-reductase - Trichoplusia ni (Cabbage looper) Length = 308 Score = 83.4 bits (197), Expect = 7e-15 Identities = 46/117 (39%), Positives = 62/117 (52%) Frame = +1 Query: 421 RRPWNNLNFQYLDLYLIHWPQAYKEDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGL 600 R L Y+DLYLIH P+A E+G P D +D ++TW ME K GL Sbjct: 117 RESLTKLGLSYVDLYLIHSPEATNENGD--PVD---------IDVLNTWNGMEEAKKLGL 165 Query: 601 VKSIGVSNFNSKQLERLLXHAXVKPVVNXVECHPYLNXKRLKEFCXXRGVXIXXYSP 771 KSIGVSNF++ L+RL+ + P VN +E HP ++L RG+ + YSP Sbjct: 166 AKSIGVSNFDTALLDRLIAGSNTVPAVNQIEVHPSKTQEKLVADSHERGIEVMAYSP 222 Score = 83.0 bits (196), Expect = 9e-15 Identities = 45/91 (49%), Positives = 59/91 (64%), Gaps = 1/91 (1%) Frame = +3 Query: 180 PXFGLGTWK-SKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIKEGVVTRED 356 P LGT+ +V QAV AI GYRHID A +YGNE+EVG+ I I++G+V RE+ Sbjct: 36 PSLALGTFGFGDIPKVRQAVLWAIQAGYRHIDTAALYGNEEEVGKGIADAIQQGLVKREE 95 Query: 357 LFITSKLWNTFHRPDLVRGALQETLEQSELS 449 LF+T+KLWN H V AL+E+L + LS Sbjct: 96 LFVTTKLWNDKHGRHQVVPALRESLTKLGLS 126 >UniRef50_Q24C22 Cluster: Oxidoreductase, aldo/keto reductase family protein; n=4; Oligohymenophorea|Rep: Oxidoreductase, aldo/keto reductase family protein - Tetrahymena thermophila SB210 Length = 297 Score = 83.4 bits (197), Expect = 7e-15 Identities = 46/112 (41%), Positives = 63/112 (56%), Gaps = 1/112 (0%) Frame = +1 Query: 439 LNFQYLDLYLIHWPQAYKEDGSLFPTD-QSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIG 615 LN +YLD LIHWP K L P D ++ +I+ ++TWKA+ L K G++K IG Sbjct: 109 LNIKYLDCVLIHWPGVSK----LPPNDPKNAQIR------LETWKALIELRKAGVIKHIG 158 Query: 616 VSNFNSKQLERLLXHAXVKPVVNXVECHPYLNXKRLKEFCXXRGVXIXXYSP 771 VSNFN L+ L+ + KP +N E HP K+ EFC G+ + YSP Sbjct: 159 VSNFNINHLQHLIEKSEFKPEMNQFEIHPLCFNKKTIEFCQKNGILVEAYSP 210 Score = 56.4 bits (130), Expect = 9e-07 Identities = 32/95 (33%), Positives = 51/95 (53%) Frame = +3 Query: 180 PXFGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIKEGVVTREDL 359 P G GT++ + + V +A+ IGY HID A VY NE+++ + I + + REDL Sbjct: 25 PQIGYGTYELRQNDCIIGVTEALKIGYTHIDTASVYRNEQDIAKVIHNPAYG--IKREDL 82 Query: 360 FITSKLWNTFHRPDLVRGALQETLEQSELSVLGSV 464 FITSK+ + + A+Q+ L + + L V Sbjct: 83 FITSKISPGEQGYEQAKKAVQDMLTRLNIKYLDCV 117 >UniRef50_Q838E0 Cluster: Oxidoreductase, aldo/keto reductase family; n=24; Bacilli|Rep: Oxidoreductase, aldo/keto reductase family - Enterococcus faecalis (Streptococcus faecalis) Length = 279 Score = 83.0 bits (196), Expect = 9e-15 Identities = 45/111 (40%), Positives = 60/111 (54%) Frame = +1 Query: 439 LNFQYLDLYLIHWPQAYKEDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGV 618 L YLDLYLIHWP + Y ++W+A+E L EG VK+IGV Sbjct: 104 LGLDYLDLYLIHWP--------------------GNNSYKESWQALETLYAEGKVKAIGV 143 Query: 619 SNFNSKQLERLLXHAXVKPVVNXVECHPYLNXKRLKEFCXXRGVXIXXYSP 771 SNF LE LL +A V PV+N VE HP L+ K +++FC + + +SP Sbjct: 144 SNFQVHHLEDLLSYAKVVPVINQVELHPKLDQKEVRDFCEKHDIKVQAWSP 194 Score = 66.5 bits (155), Expect = 9e-10 Identities = 35/92 (38%), Positives = 49/92 (53%) Frame = +3 Query: 180 PXFGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIKEGVVTREDL 359 P GLG ++ E + V++ I GYR ID A +YGNE G I + + + REDL Sbjct: 18 PGMGLGVFQIPDEETAKVVEEGIINGYRLIDTAQIYGNESGTGAGIKAGLAATGLNREDL 77 Query: 360 FITSKLWNTFHRPDLVRGALQETLEQSELSVL 455 F+TSK+WN D A ++LE+ L L Sbjct: 78 FVTSKVWNAHISYDETIQAFNDSLERLGLDYL 109 >UniRef50_Q8F1G4 Cluster: Aldehyde reductase; n=8; Bacteria|Rep: Aldehyde reductase - Leptospira interrogans Length = 278 Score = 82.2 bits (194), Expect = 2e-14 Identities = 40/87 (45%), Positives = 58/87 (66%), Gaps = 1/87 (1%) Frame = +3 Query: 180 PXFGLGTWKSKPG-EVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIKEGVVTRED 356 P GLG WK+K G E +AV +A++ GYRHID A +Y NE +VG+A I+E + R++ Sbjct: 21 PILGLGVWKTKSGKECKEAVLNALEAGYRHIDTARIYDNEVDVGQA----IRESGIPRKE 76 Query: 357 LFITSKLWNTFHRPDLVRGALQETLEQ 437 +FIT+KLWN D R AL+ +L++ Sbjct: 77 IFITTKLWNADQGSDKTRKALENSLDR 103 Score = 68.1 bits (159), Expect = 3e-10 Identities = 39/113 (34%), Positives = 56/113 (49%) Frame = +1 Query: 433 NNLNFQYLDLYLIHWPQAYKEDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSI 612 + L ++DLYLIH+P K +D+WK +E L + L K+I Sbjct: 102 DRLGIDFVDLYLIHFPVTSKR--------------------MDSWKELEKLYHDKLCKAI 141 Query: 613 GVSNFNSKQLERLLXHAXVKPVVNXVECHPYLNXKRLKEFCXXRGVXIXXYSP 771 GVSN+ L LL ++ + P VN VE HP+LN L E+C + + YSP Sbjct: 142 GVSNYTIIHLTELLKNSQITPAVNQVEFHPFLNQIHLLEYCKKHKIQLEAYSP 194 >UniRef50_Q7PM68 Cluster: ENSANGP00000014386; n=1; Anopheles gambiae str. PEST|Rep: ENSANGP00000014386 - Anopheles gambiae str. PEST Length = 310 Score = 82.2 bits (194), Expect = 2e-14 Identities = 38/118 (32%), Positives = 59/118 (50%) Frame = +1 Query: 418 CRRPWNNLNFQYLDLYLIHWPQAYKEDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEG 597 CR + L Y+DLYL+H P A + + + + W +E +EG Sbjct: 98 CRMTLDRLGMDYVDLYLMHTPVALQSEKKCARNGTKLNAIDDSIAPTEAWIGLEQCYQEG 157 Query: 598 LVKSIGVSNFNSKQLERLLXHAXVKPVVNXVECHPYLNXKRLKEFCXXRGVXIXXYSP 771 L +SIGVSNFN Q+ LL A + P VN +EC N + +++FC + + + Y+P Sbjct: 158 LCRSIGVSNFNEHQINALLSDASIVPAVNQIECSIGFNQRPMRKFCQQQNILVMGYTP 215 Score = 81.4 bits (192), Expect = 3e-14 Identities = 41/87 (47%), Positives = 55/87 (63%), Gaps = 1/87 (1%) Frame = +3 Query: 180 PXFGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIKE-GVVTRED 356 P GLGT+ + +A++ AID+GYR D A YGNE VGEAI KI+E +TR+D Sbjct: 18 PTIGLGTYSILGADGKEAIRTAIDVGYRMFDTAVAYGNEAIVGEAIREKIRECNNLTRDD 77 Query: 357 LFITSKLWNTFHRPDLVRGALQETLEQ 437 FI SKL ++HR DLV + TL++ Sbjct: 78 FFIISKLSGSYHRQDLVEKCCRMTLDR 104 >UniRef50_A6SI80 Cluster: Putative uncharacterized protein; n=1; Botryotinia fuckeliana B05.10|Rep: Putative uncharacterized protein - Botryotinia fuckeliana B05.10 Length = 253 Score = 82.2 bits (194), Expect = 2e-14 Identities = 44/122 (36%), Positives = 64/122 (52%), Gaps = 7/122 (5%) Frame = +1 Query: 421 RRPWNNLNFQYLDLYLIHWPQA--YKEDGSLFP-----TDQSGKIQFSDVDYVDTWKAME 579 R+ + Y DL+++H+P A Y + +P +D+ G +Q S +TW+AME Sbjct: 71 RKQLADWGIDYFDLFIVHFPVALRYVDPAVRYPPGWQYSDKEGDVQQSKASIQETWQAME 130 Query: 580 PLVKEGLVKSIGVSNFNSKQLERLLXHAXVKPVVNXVECHPYLNXKRLKEFCXXRGVXIX 759 LV EGL KSIGVSNF L LL +A ++P +E HPYL L + G+ + Sbjct: 131 KLVDEGLAKSIGVSNFQGALLIDLLRYARIRPATLQIEHHPYLVQNTLLKLAESEGIKVT 190 Query: 760 XY 765 Y Sbjct: 191 AY 192 >UniRef50_P14065 Cluster: Protein GCY; n=13; Saccharomycetales|Rep: Protein GCY - Saccharomyces cerevisiae (Baker's yeast) Length = 312 Score = 82.2 bits (194), Expect = 2e-14 Identities = 46/121 (38%), Positives = 64/121 (52%), Gaps = 10/121 (8%) Frame = +1 Query: 439 LNFQYLDLYLIHWPQ----AY--KEDGSLFPTDQSGK--IQFSDVDYVDTWKAMEPLVKE 594 L Y+DLYL+HWP AY ED PT + G + ++ +++ TW+ M+ L K Sbjct: 101 LGLDYVDLYLMHWPARLDPAYIKNEDILSVPTKKDGSRAVDITNWNFIKTWELMQELPKT 160 Query: 595 GLVKSIGVSNFNSKQLERLLXHAXVK--PVVNXVECHPYLNXKRLKEFCXXRGVXIXXYS 768 G K++GVSNF+ L+ LL K P N VE HP L L FC +G+ + YS Sbjct: 161 GKTKAVGVSNFSINNLKDLLASQGNKLTPAANQVEIHPLLPQDELINFCKSKGIVVEAYS 220 Query: 769 P 771 P Sbjct: 221 P 221 Score = 77.0 bits (181), Expect = 6e-13 Identities = 40/87 (45%), Positives = 58/87 (66%), Gaps = 1/87 (1%) Frame = +3 Query: 180 PXFGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIKEGVVTREDL 359 P GLGTW+SK + +AV A+ GYRHID A +Y NE +VG+A IK+ V RE++ Sbjct: 21 PQIGLGTWQSKENDAYKAVLTALKDGYRHIDTAAIYRNEDQVGQA----IKDSGVPREEI 76 Query: 360 FITSKLWNT-FHRPDLVRGALQETLEQ 437 F+T+KLW T H P++ AL ++L++ Sbjct: 77 FVTTKLWCTQHHEPEV---ALDQSLKR 100 >UniRef50_Q4JX70 Cluster: Putative oxidoreductase; n=1; Corynebacterium jeikeium K411|Rep: Putative oxidoreductase - Corynebacterium jeikeium (strain K411) Length = 285 Score = 81.8 bits (193), Expect = 2e-14 Identities = 35/68 (51%), Positives = 46/68 (67%) Frame = +3 Query: 180 PXFGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIKEGVVTREDL 359 P GLG W+ + +V+ AI+ GYRHID A +YGNE+ VG A+ +K G V RE+L Sbjct: 20 PQLGLGVWQLSDEDTYTSVRAAIETGYRHIDTAAIYGNEEAVGRAVADAVKAGDVQREEL 79 Query: 360 FITSKLWN 383 FIT+KLWN Sbjct: 80 FITTKLWN 87 Score = 43.6 bits (98), Expect = 0.007 Identities = 33/111 (29%), Positives = 47/111 (42%) Frame = +1 Query: 439 LNFQYLDLYLIHWPQAYKEDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGV 618 L Y+DLYL+HWP P S +V + +M + + G SIGV Sbjct: 104 LGMDYVDLYLLHWP---------CPQADS---------FVQAYDSMAEIQQSGGATSIGV 145 Query: 619 SNFNSKQLERLLXHAXVKPVVNXVECHPYLNXKRLKEFCXXRGVXIXXYSP 771 NF + L+ L A P VN +E HP + + RG+ +SP Sbjct: 146 CNFYPEALDAL-KQAGHTPAVNQIEIHPGFSQAEQRSDNRDRGIVTEAWSP 195 >UniRef50_Q03TW0 Cluster: Aldo/keto reductase of diketogulonate reductase family; n=1; Lactobacillus brevis ATCC 367|Rep: Aldo/keto reductase of diketogulonate reductase family - Lactobacillus brevis (strain ATCC 367 / JCM 1170) Length = 293 Score = 81.4 bits (192), Expect = 3e-14 Identities = 43/113 (38%), Positives = 58/113 (51%) Frame = +1 Query: 433 NNLNFQYLDLYLIHWPQAYKEDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSI 612 + L YLDLYLIHWP Y+D+W+AME L K G +K+I Sbjct: 104 DKLGLDYLDLYLIHWPAP---------------------GYLDSWRAMEDLYKAGKIKNI 142 Query: 613 GVSNFNSKQLERLLXHAXVKPVVNXVECHPYLNXKRLKEFCXXRGVXIXXYSP 771 GVSNFN Q+ +L H VKPVV+ +E HPY + + +G+ +SP Sbjct: 143 GVSNFNQTQMADILAHGTVKPVVDQIETHPYFQQNDMHAYLESQGILHEAWSP 195 Score = 76.2 bits (179), Expect = 1e-12 Identities = 43/93 (46%), Positives = 57/93 (61%), Gaps = 1/93 (1%) Frame = +3 Query: 180 PXFGLGTWKSKPGEVTQ-AVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIKEGVVTRED 356 P GLG ++ E T+ A+K A+ GYRHID A YGNE+ VGEA I+E V R+ Sbjct: 23 PQLGLGVFQVDNAEDTKNAIKWALAAGYRHIDTAAYYGNEQWVGEA----IRESDVPRDQ 78 Query: 357 LFITSKLWNTFHRPDLVRGALQETLEQSELSVL 455 +F+TSKLWN+ D + A QETL++ L L Sbjct: 79 IFVTSKLWNSVRGYDETQAAFQETLDKLGLDYL 111 >UniRef50_Q01HB5 Cluster: OSIGBa0136O08-OSIGBa0153H12.9 protein; n=4; Oryza sativa|Rep: OSIGBa0136O08-OSIGBa0153H12.9 protein - Oryza sativa (Rice) Length = 337 Score = 81.4 bits (192), Expect = 3e-14 Identities = 49/121 (40%), Positives = 67/121 (55%), Gaps = 4/121 (3%) Frame = +1 Query: 421 RRPWNNLNFQYLDLYLIHWPQAY-KED--GSLFPTDQS-GKIQFSDVDYVDTWKAMEPLV 588 R + L Y+DL+LIHWP A K+D G L D S G + F D W+ ME Sbjct: 114 RESLSRLGLDYVDLFLIHWPVAIGKKDAAGELTWDDLSRGLVPF---DMEGVWRGMEECH 170 Query: 589 KEGLVKSIGVSNFNSKQLERLLXHAXVKPVVNXVECHPYLNXKRLKEFCXXRGVXIXXYS 768 + GL +SIGVSNF++ ++ RLL A V P VN VE + ++++E C GV + YS Sbjct: 171 RLGLARSIGVSNFSAAKMSRLLALAAVPPAVNQVEMNVGWRQEKVREVCGEGGVVVAAYS 230 Query: 769 P 771 P Sbjct: 231 P 231 Score = 63.7 bits (148), Expect = 6e-09 Identities = 34/88 (38%), Positives = 50/88 (56%), Gaps = 2/88 (2%) Frame = +3 Query: 180 PXFGLGTWKSKP-GEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIKEG-VVTRE 353 P G GT S P ++ + A+ +GYRH+D A VYG E VG A+ ++ G V +R Sbjct: 32 PVLGFGTGSSTPPADLAATIAHAVRLGYRHLDTAAVYGTEGAVGAAVAEAVRCGAVASRG 91 Query: 354 DLFITSKLWNTFHRPDLVRGALQETLEQ 437 +LF+T+KL P V AL+E+L + Sbjct: 92 ELFVTTKLSMADAHPPRVVAALRESLSR 119 >UniRef50_Q03XK0 Cluster: Aldo/keto reductase of diketogulonate reductase family; n=3; Lactobacillales|Rep: Aldo/keto reductase of diketogulonate reductase family - Leuconostoc mesenteroides subsp. mesenteroides (strain ATCC 8293 /NCDO 523) Length = 292 Score = 81.0 bits (191), Expect = 4e-14 Identities = 42/93 (45%), Positives = 55/93 (59%), Gaps = 1/93 (1%) Frame = +3 Query: 180 PXFGLGTWK-SKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIKEGVVTRED 356 P G G ++ + G QAV DAI GYR ID A YGNE+EVGEAI I +G+V RE+ Sbjct: 13 PLLGFGVFQVQEKGAAKQAVLDAIKTGYRLIDTAASYGNEREVGEAILEAINQGIVKREE 72 Query: 357 LFITSKLWNTFHRPDLVRGALQETLEQSELSVL 455 LF+TSK+W A+Q +L++ L L Sbjct: 73 LFVTSKMWVQDVSAQQATAAIQSSLQRLNLDYL 105 Score = 59.7 bits (138), Expect = 1e-07 Identities = 37/111 (33%), Positives = 56/111 (50%) Frame = +1 Query: 439 LNFQYLDLYLIHWPQAYKEDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGV 618 LN YLDLYLIH P ++DV W+AME + G +K+IGV Sbjct: 100 LNLDYLDLYLIHQP-------------------YNDV--FGAWRAMESAYRSGQLKAIGV 138 Query: 619 SNFNSKQLERLLXHAXVKPVVNXVECHPYLNXKRLKEFCXXRGVXIXXYSP 771 SNF+ QL L + +KP++N +E +P+ K+ + GV + ++P Sbjct: 139 SNFDIAQLTNLAEFSDIKPMLNQIEVNPFQQNKKDITYFSQYGVQVEAWAP 189 >UniRef50_P22045 Cluster: Probable reductase; n=101; cellular organisms|Rep: Probable reductase - Leishmania major Length = 284 Score = 81.0 bits (191), Expect = 4e-14 Identities = 46/111 (41%), Positives = 63/111 (56%) Frame = +1 Query: 439 LNFQYLDLYLIHWPQAYKEDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGV 618 L Y+DLYLIHWP+ K+ S + GK Y+D+W+A E L KE V++IGV Sbjct: 101 LGVDYIDLYLIHWPRG-KDILS-----KEGK------KYLDSWRAFEQLYKEKKVRAIGV 148 Query: 619 SNFNSKQLERLLXHAXVKPVVNXVECHPYLNXKRLKEFCXXRGVXIXXYSP 771 SNF+ LE +L V P+VN VE HP N L+ FC + + + +SP Sbjct: 149 SNFHIHHLEDVLAMCTVTPMVNQVELHPLNNQADLRAFCDAKQIKVEAWSP 199 Score = 75.8 bits (178), Expect = 1e-12 Identities = 40/87 (45%), Positives = 54/87 (62%), Gaps = 1/87 (1%) Frame = +3 Query: 180 PXFGLGTWKSKPGEVTQ-AVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIKEGVVTRED 356 P FGLG W+S GEVT+ AV A+ GYRHID A +Y NE+ VG + + V RED Sbjct: 18 PQFGLGVWQSPAGEVTENAVNWALCAGYRHIDTAAIYKNEESVGAGL----RASGVPRED 73 Query: 357 LFITSKLWNTFHRPDLVRGALQETLEQ 437 +FIT+KLWNT + A +E+ ++ Sbjct: 74 VFITTKLWNTEQGYESTLAAFEESRQK 100 >UniRef50_Q7R2T6 Cluster: GLP_291_56367_57278; n=1; Giardia lamblia ATCC 50803|Rep: GLP_291_56367_57278 - Giardia lamblia ATCC 50803 Length = 303 Score = 80.6 bits (190), Expect = 5e-14 Identities = 41/114 (35%), Positives = 55/114 (48%), Gaps = 2/114 (1%) Frame = +1 Query: 436 NLNFQYLDLYLIHWPQAYKE--DGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKS 609 +L +YLD++L+HWP A K D +D G TW+AME V + + Sbjct: 90 DLQLEYLDVFLMHWPLAIKHLADRDYASSDGKGGTLLGTTPIRKTWEAMEACVDKKQTRF 149 Query: 610 IGVSNFNSKQLERLLXHAXVKPVVNXVECHPYLNXKRLKEFCXXRGVXIXXYSP 771 IGVSN + L LL + +KP N E PY RL EFC G+ + Y P Sbjct: 150 IGVSNMGTAMLVDLLSYCRIKPFTNQFESQPYFPNDRLIEFCNSNGIYVTAYRP 203 Score = 79.4 bits (187), Expect = 1e-13 Identities = 40/94 (42%), Positives = 53/94 (56%), Gaps = 2/94 (2%) Frame = +3 Query: 180 PXFGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIKEGV--VTRE 353 P G GT+ + E A++ A+ +GYRH DCAY YGNE+ +GE + V RE Sbjct: 6 PCVGFGTYLVEDPE---AIRSAVKLGYRHFDCAYRYGNERMIGEVFKEIFNDDSYGVKRE 62 Query: 354 DLFITSKLWNTFHRPDLVRGALQETLEQSELSVL 455 DL+I SKLW FH P+ V + ETL +L L Sbjct: 63 DLWIVSKLWPNFHEPEKVAYQISETLRDLQLEYL 96 >UniRef50_Q9HGY0 Cluster: Glycerol dehydrogenase; n=8; Saccharomycetaceae|Rep: Glycerol dehydrogenase - Zygosaccharomyces rouxii (Candida mogii) Length = 310 Score = 80.6 bits (190), Expect = 5e-14 Identities = 46/121 (38%), Positives = 66/121 (54%), Gaps = 10/121 (8%) Frame = +1 Query: 439 LNFQYLDLYLIHWPQAYK----EDGSLFPTDQSGKIQFSDVD----YVDTWKAMEPLVKE 594 L Y+ LYL+HWP + +DG+LF + DVD ++ TW+ M+ L++ Sbjct: 100 LGLDYVGLYLVHWPVPLRTENIKDGNLFQFAEKPDGS-KDVDLEWNFIKTWELMQKLLES 158 Query: 595 GLVKSIGVSNFNSKQLERLLXHAXVK--PVVNXVECHPYLNXKRLKEFCXXRGVXIXXYS 768 G K+IGVSNF+ L+ LL K P VN VE HP L + L ++C +G+ I YS Sbjct: 159 GKTKAIGVSNFSVNNLKDLLAAPTTKVTPAVNQVEFHPLLPQEELIQYCSEKGIVIEAYS 218 Query: 769 P 771 P Sbjct: 219 P 219 Score = 79.0 bits (186), Expect = 1e-13 Identities = 43/93 (46%), Positives = 60/93 (64%) Frame = +3 Query: 180 PXFGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIKEGVVTREDL 359 P GLGTW+SK E +AV +A+ GYRHID A VYGNE EVG+A I++ V R ++ Sbjct: 20 PQVGLGTWRSKENEGYKAVIEALKAGYRHIDGAAVYGNEGEVGKA----IQDSGVPRNEI 75 Query: 360 FITSKLWNTFHRPDLVRGALQETLEQSELSVLG 458 F+T+KLW T R + AL ++L++ L +G Sbjct: 76 FLTTKLWCTHQRNP--QEALDQSLQRLGLDYVG 106 >UniRef50_Q6C2L0 Cluster: Yarrowia lipolytica chromosome F of strain CLIB122 of Yarrowia lipolytica; n=3; Yarrowia lipolytica|Rep: Yarrowia lipolytica chromosome F of strain CLIB122 of Yarrowia lipolytica - Yarrowia lipolytica (Candida lipolytica) Length = 324 Score = 80.6 bits (190), Expect = 5e-14 Identities = 42/118 (35%), Positives = 64/118 (54%), Gaps = 6/118 (5%) Frame = +1 Query: 436 NLNFQYLDLYLIHWPQAYKEDG----SLFPTDQSGKIQFSDV--DYVDTWKAMEPLVKEG 597 +L+ Y+DL L+HWP + D +++ + G +++SD D++ T+K +E G Sbjct: 97 DLSLDYVDLLLVHWPVSLLADSDDPRAIYLVNTDGSVRYSDSLDDWITTYKQIEEEKLSG 156 Query: 598 LVKSIGVSNFNSKQLERLLXHAXVKPVVNXVECHPYLNXKRLKEFCXXRGVXIXXYSP 771 KSIGVSN + L+RLL P VN E HPYL K+ EF G+ + +SP Sbjct: 157 RTKSIGVSNVSEVYLKRLLDQVKTVPAVNQFEIHPYLPQKKEIEFNEKHGILVTAFSP 214 Score = 73.7 bits (173), Expect = 6e-12 Identities = 35/71 (49%), Positives = 48/71 (67%) Frame = +3 Query: 180 PXFGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIKEGVVTREDL 359 P GLGT + G V + V AI GYRHID A++YG+E +VG+ I I E +V RE+L Sbjct: 16 PALGLGT--ASDGNVEEVVYAAIKNGYRHIDTAFIYGSEVDVGKGIKRAIDEELVKRENL 73 Query: 360 FITSKLWNTFH 392 F+T+K+W TF+ Sbjct: 74 FVTTKVWPTFY 84 >UniRef50_A2QB88 Cluster: Contig An01c0460, complete genome. precursor; n=1; Aspergillus niger|Rep: Contig An01c0460, complete genome. precursor - Aspergillus niger Length = 351 Score = 80.6 bits (190), Expect = 5e-14 Identities = 37/74 (50%), Positives = 45/74 (60%) Frame = +1 Query: 550 DYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLXHAXVKPVVNXVECHPYLNXKRLKE 729 DY TW AME LV +G +K IGVSNFN +LERLL A + P VN +E HPYL L Sbjct: 178 DYPSTWAAMESLVDKGKLKMIGVSNFNILKLERLLGSARIPPAVNQIELHPYLPQVELVR 237 Query: 730 FCXXRGVXIXXYSP 771 FC G+ + + P Sbjct: 238 FCKANGIHLVAHQP 251 Score = 78.6 bits (185), Expect = 2e-13 Identities = 45/96 (46%), Positives = 59/96 (61%), Gaps = 2/96 (2%) Frame = +3 Query: 168 EXLFPXFGLGTWKSKPGE--VTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIKEGV 341 E FP GLGT++ G V +AV A+ GYRHID A YGNE EVGEA IKE Sbjct: 43 EMTFPAVGLGTFQGDAGNRGVKEAVLQALRCGYRHIDTATAYGNEIEVGEA----IKESR 98 Query: 342 VTREDLFITSKLWNTFHRPDLVRGALQETLEQSELS 449 + RE++ +T+KL T+HR V AL +LE+ +L+ Sbjct: 99 IPREEIIVTTKLAQTWHRVSDVERALDLSLERLQLN 134 >UniRef50_P06632 Cluster: 2,5-diketo-D-gluconic acid reductase A; n=8; Actinomycetales|Rep: 2,5-diketo-D-gluconic acid reductase A - Corynebacterium sp. (strain ATCC 31090) Length = 278 Score = 80.6 bits (190), Expect = 5e-14 Identities = 39/89 (43%), Positives = 56/89 (62%) Frame = +3 Query: 180 PXFGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIKEGVVTREDL 359 P G G +K P + +AV++A+++GYRHID A +YGNE+ VG AI + + R+DL Sbjct: 15 PQLGYGVFKVPPADTQRAVEEALEVGYRHIDTAAIYGNEEGVGAAIAA----SGIARDDL 70 Query: 360 FITSKLWNTFHRPDLVRGALQETLEQSEL 446 FIT+KLWN H D A+ E+L + L Sbjct: 71 FITTKLWNDRHDGDEPAAAIAESLAKLAL 99 Score = 54.4 bits (125), Expect = 4e-06 Identities = 34/111 (30%), Positives = 48/111 (43%) Frame = +1 Query: 439 LNFQYLDLYLIHWPQAYKEDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGV 618 L +DLYL+HWP ++ YV W+ M L GL +SIGV Sbjct: 97 LALDQVDLYLVHWPTPAADN------------------YVHAWEKMIELRAAGLTRSIGV 138 Query: 619 SNFNSKQLERLLXHAXVKPVVNXVECHPYLNXKRLKEFCXXRGVXIXXYSP 771 SN LER++ V P VN +E HP + + ++ V I + P Sbjct: 139 SNHLVPHLERIVAATGVVPAVNQIELHPAYQQREITDWAAAHDVKIESWGP 189 >UniRef50_Q23320 Cluster: Putative uncharacterized protein; n=4; Caenorhabditis|Rep: Putative uncharacterized protein - Caenorhabditis elegans Length = 320 Score = 80.2 bits (189), Expect = 6e-14 Identities = 37/91 (40%), Positives = 57/91 (62%) Frame = +3 Query: 174 LFPXFGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIKEGVVTRE 353 L P GLGTW+ E +++A+ GYRHID A +Y NE ++G+A+ EG++ RE Sbjct: 15 LMPSIGLGTWQMTGEEGKTVIRNAVLAGYRHIDTATLYQNEHQIGDALAELFAEGILKRE 74 Query: 354 DLFITSKLWNTFHRPDLVRGALQETLEQSEL 446 D+FIT+K + PD+V AL+ +L++ L Sbjct: 75 DIFITTKAFCHEVAPDVVEEALRNSLKRLRL 105 Score = 70.1 bits (164), Expect = 7e-11 Identities = 41/116 (35%), Positives = 55/116 (47%) Frame = +1 Query: 421 RRPWNNLNFQYLDLYLIHWPQAYKEDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGL 600 R L Y+DLYL H P + K+DGS SDV D W+ E + GL Sbjct: 97 RNSLKRLRLDYVDLYLAHIPASTKDDGSFR----------SDVKVEDIWRGFEKVYGLGL 146 Query: 601 VKSIGVSNFNSKQLERLLXHAXVKPVVNXVECHPYLNXKRLKEFCXXRGVXIXXYS 768 K+IGVSNFN Q+ R++ V + +E H YL K +E C + I Y+ Sbjct: 147 TKAIGVSNFNESQIVRIMNIQKVPIHASQLELHLYLPQKAHRELCKKHNILITAYA 202 >UniRef50_UPI00015B40FA Cluster: PREDICTED: similar to CG2767-PA; n=2; Nasonia vitripennis|Rep: PREDICTED: similar to CG2767-PA - Nasonia vitripennis Length = 356 Score = 79.8 bits (188), Expect = 9e-14 Identities = 40/113 (35%), Positives = 63/113 (55%), Gaps = 3/113 (2%) Frame = +1 Query: 439 LNFQYLDLYLIHWPQAYKEDGSLFPT--DQSGKIQF-SDVDYVDTWKAMEPLVKEGLVKS 609 L +Y+++YLIH P A+ +D + + G + +D D+V W+AME VK G V+S Sbjct: 122 LGLEYVNMYLIHKPFAFVKDKYKYEPALNPDGSVVLDTDTDHVAIWRAMEKQVKAGRVRS 181 Query: 610 IGVSNFNSKQLERLLXHAXVKPVVNXVECHPYLNXKRLKEFCXXRGVXIXXYS 768 IG+SNFN QL + HA +KP +E Y + ++E C R + + +S Sbjct: 182 IGLSNFNKSQLLNVYEHAEIKPSNLQIELQAYNQQRPMRELCAERNITVTAFS 234 Score = 72.5 bits (170), Expect = 1e-11 Identities = 37/86 (43%), Positives = 52/86 (60%) Frame = +3 Query: 180 PXFGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIKEGVVTREDL 359 P GLGTW+ P + AV A++ GYRHID A+ YGNE+ +G+ + +G REDL Sbjct: 37 PMIGLGTWQMPPEAIEVAVTAALESGYRHIDTAFTYGNEEAIGKTLKKWFDKG-GKREDL 95 Query: 360 FITSKLWNTFHRPDLVRGALQETLEQ 437 FIT+KL R + V L+ +LE+ Sbjct: 96 FITTKLPPIGMRAEYVESYLKLSLEK 121 >UniRef50_UPI00005A2CCB Cluster: PREDICTED: similar to Aldose reductase (AR) (Aldehyde reductase); n=1; Canis lupus familiaris|Rep: PREDICTED: similar to Aldose reductase (AR) (Aldehyde reductase) - Canis familiaris Length = 182 Score = 79.8 bits (188), Expect = 9e-14 Identities = 37/71 (52%), Positives = 48/71 (67%) Frame = +3 Query: 180 PXFGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIKEGVVTREDL 359 P GL TWKS P +VT+AVK +D+GY HIDC + N++EVG A+ K+K V REDL Sbjct: 32 PIMGLATWKSPPSKVTEAVKVVMDLGYCHIDCTHKLQNKREVGLAVQEKLKGQGVKREDL 91 Query: 360 FITSKLWNTFH 392 I S+L +T H Sbjct: 92 SILSELQHTHH 102 >UniRef50_Q7N0E4 Cluster: 2,5-diketo-D-gluconic acid reductase A; n=2; Bacteria|Rep: 2,5-diketo-D-gluconic acid reductase A - Photorhabdus luminescens subsp. laumondii Length = 292 Score = 79.8 bits (188), Expect = 9e-14 Identities = 40/89 (44%), Positives = 56/89 (62%) Frame = +3 Query: 180 PXFGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIKEGVVTREDL 359 P GLG+W S ++ + + A+DIGYR ID A +Y NEK VG A ++E + RED+ Sbjct: 16 PQLGLGSWASDDQQIAETIHAALDIGYRAIDTAAIYNNEKGVGNA----LQETDIPREDI 71 Query: 360 FITSKLWNTFHRPDLVRGALQETLEQSEL 446 F+T+KLWN H R AL E+LE+ +L Sbjct: 72 FVTTKLWNDRHLD--ARAALTESLEKLQL 98 Score = 74.9 bits (176), Expect = 2e-12 Identities = 41/111 (36%), Positives = 57/111 (51%) Frame = +1 Query: 439 LNFQYLDLYLIHWPQAYKEDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGV 618 L Y+DLYLIHWP P DQ YV W+ + L KEGL++SIGV Sbjct: 96 LQLDYVDLYLIHWPAP--------PQDQ----------YVGAWQQLIELQKEGLIRSIGV 137 Query: 619 SNFNSKQLERLLXHAXVKPVVNXVECHPYLNXKRLKEFCXXRGVXIXXYSP 771 SNF + ++RL+ V PV+N +E HP L ++L + + +SP Sbjct: 138 SNFQPEHIQRLINETGVHPVINQIELHPLLQQRQLHAWNATHNIVTESWSP 188 >UniRef50_Q1VRG6 Cluster: YvgN; n=1; Psychroflexus torquis ATCC 700755|Rep: YvgN - Psychroflexus torquis ATCC 700755 Length = 280 Score = 79.8 bits (188), Expect = 9e-14 Identities = 45/113 (39%), Positives = 59/113 (52%), Gaps = 2/113 (1%) Frame = +1 Query: 439 LNFQYLDLYLIHWPQAYKEDGSLFPTDQSGKIQFSDVDYV--DTWKAMEPLVKEGLVKSI 612 L+ Y+DLYLIHWP + I + D DTW+AME L EG +KS+ Sbjct: 95 LDLNYIDLYLIHWP--------------ANAINYKDWQKTNADTWRAMEELQAEGKIKSL 140 Query: 613 GVSNFNSKQLERLLXHAXVKPVVNXVECHPYLNXKRLKEFCXXRGVXIXXYSP 771 GVSNF + LE L A V P VN +E HP ++ EFC G+ + +SP Sbjct: 141 GVSNFWPEHLEALFQTAKVSPSVNQIEFHPGYWQPQVTEFCKNHGIAVESWSP 193 Score = 60.9 bits (141), Expect = 4e-08 Identities = 35/93 (37%), Positives = 57/93 (61%), Gaps = 1/93 (1%) Frame = +3 Query: 180 PXFGLGTWKSKPGEVTQAV-KDAIDIGYRHIDCAYVYGNEKEVGEAITSKIKEGVVTRED 356 P G GT+K+ E +++ K A+ +GYR ID +Y NE+ VG+AI ++ GV+ RE+ Sbjct: 12 PIVGFGTYKANEEEGIKSIQKSALTLGYRLIDTVAIYQNEEAVGKAIKAR---GVL-REE 67 Query: 357 LFITSKLWNTFHRPDLVRGALQETLEQSELSVL 455 +F+T+KLW R AL E+L + +L+ + Sbjct: 68 IFVTTKLWRENLGYKQTRIALDESLRKLDLNYI 100 >UniRef50_Q03X85 Cluster: Aldo/keto reductase of diketogulonate reductase family; n=1; Leuconostoc mesenteroides subsp. mesenteroides ATCC 8293|Rep: Aldo/keto reductase of diketogulonate reductase family - Leuconostoc mesenteroides subsp. mesenteroides (strain ATCC 8293 /NCDO 523) Length = 288 Score = 79.8 bits (188), Expect = 9e-14 Identities = 37/86 (43%), Positives = 53/86 (61%) Frame = +3 Query: 180 PXFGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIKEGVVTREDL 359 P G G ++ E QAV DAI+ GYR ID A VYGNE E G+ + I VV RE+L Sbjct: 13 PQLGFGVFQIPAEETKQAVVDAINAGYRSIDTARVYGNEAETGQGVNEAIANAVVAREEL 72 Query: 360 FITSKLWNTFHRPDLVRGALQETLEQ 437 F+T+KLW + + +GA+ ++L++ Sbjct: 73 FLTTKLWLSEFSYEAAKGAIDDSLKK 98 Score = 37.5 bits (83), Expect = 0.45 Identities = 22/78 (28%), Positives = 34/78 (43%), Gaps = 4/78 (5%) Frame = +1 Query: 550 DYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLXHAXVK----PVVNXVECHPYLNXK 717 D +KA+ +G VKSIG+SNF + + P ++ +E HPY K Sbjct: 115 DVYGAYKALAEAQADGKVKSIGISNFYPAKFVEFIKVIKTMNLPVPQIDQIEFHPYYQEK 174 Query: 718 RLKEFCXXRGVXIXXYSP 771 ++ GV I + P Sbjct: 175 VARQLHDKYGVQIEAWGP 192 >UniRef50_A7BA05 Cluster: Putative uncharacterized protein; n=1; Actinomyces odontolyticus ATCC 17982|Rep: Putative uncharacterized protein - Actinomyces odontolyticus ATCC 17982 Length = 292 Score = 79.8 bits (188), Expect = 9e-14 Identities = 38/85 (44%), Positives = 54/85 (63%) Frame = +3 Query: 180 PXFGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIKEGVVTREDL 359 P G GT+K P + AV A+++GYRHID A +YGNE EVG A ++ + REDL Sbjct: 28 PVLGFGTYKVAPEDTYDAVSRALEVGYRHIDTAQMYGNEAEVGAA----LEASGIAREDL 83 Query: 360 FITSKLWNTFHRPDLVRGALQETLE 434 FIT+K+ N+ H PD +++ +LE Sbjct: 84 FITTKVDNSNHEPDRAAASIRRSLE 108 Score = 53.2 bits (122), Expect = 8e-06 Identities = 35/121 (28%), Positives = 52/121 (42%) Frame = +1 Query: 409 AVPCRRPWNNLNFQYLDLYLIHWPQAYKEDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLV 588 A RR +L Y+DL L+HWP PT G + W A+E Sbjct: 100 AASIRRSLEDLRTDYVDLLLVHWP---------LPTLYGGDVALP-------WPALEDAF 143 Query: 589 KEGLVKSIGVSNFNSKQLERLLXHAXVKPVVNXVECHPYLNXKRLKEFCXXRGVXIXXYS 768 G ++IG+SN+ + +E + A V P V VE HP+ L+ + G+ +S Sbjct: 144 NAGGARAIGLSNYEREHVEAVREVATVAPHVLQVESHPFFPNADLRAYAQGLGMVFEAWS 203 Query: 769 P 771 P Sbjct: 204 P 204 >UniRef50_Q4P4P1 Cluster: Putative uncharacterized protein; n=1; Ustilago maydis|Rep: Putative uncharacterized protein - Ustilago maydis (Smut fungus) Length = 322 Score = 79.4 bits (187), Expect = 1e-13 Identities = 41/111 (36%), Positives = 60/111 (54%) Frame = +1 Query: 439 LNFQYLDLYLIHWPQAYKEDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGV 618 LN Y+D+YL+H P + L + WKA+E V G +K+IGV Sbjct: 113 LNVDYMDMYLMHSPGTMGAEKRL-----------------EAWKALEEAVDAGKIKTIGV 155 Query: 619 SNFNSKQLERLLXHAXVKPVVNXVECHPYLNXKRLKEFCXXRGVXIXXYSP 771 SNF+ ++L+ LL + +KP VN +E HP+ + L+E C RG+ I YSP Sbjct: 156 SNFDVEELDHLLANCRIKPAVNQIESHPFFAHEELREACISRGIHIQAYSP 206 Score = 69.3 bits (162), Expect = 1e-10 Identities = 37/87 (42%), Positives = 50/87 (57%), Gaps = 1/87 (1%) Frame = +3 Query: 180 PXFGLGTWKS-KPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIKEGVVTRED 356 P LG +K+ G A K A D GYRHID A Y NE+ VG A+ KE V R + Sbjct: 28 PQVALGVYKAPNDGSTENACKWAFDAGYRHIDSAARYMNEESVGRALAEWTKENNVPRSE 87 Query: 357 LFITSKLWNTFHRPDLVRGALQETLEQ 437 +FITSKLW+ H D A++++L++ Sbjct: 88 IFITSKLWDADH--DKAAAAIEDSLKK 112 >UniRef50_Q4PHK0 Cluster: Putative uncharacterized protein; n=1; Ustilago maydis|Rep: Putative uncharacterized protein - Ustilago maydis (Smut fungus) Length = 355 Score = 79.0 bits (186), Expect = 1e-13 Identities = 41/113 (36%), Positives = 57/113 (50%), Gaps = 2/113 (1%) Frame = +1 Query: 439 LNFQYLDLYLIHWP-QAYKEDGSLFPTDQSGKIQFS-DVDYVDTWKAMEPLVKEGLVKSI 612 L Y+DL L+HWP K P ++ G D TW+ ME L G K+I Sbjct: 130 LGLDYVDLLLVHWPVPLVKRGDEKIPLNEDGSRAIDRDWSPEQTWELMEKLPATGKTKAI 189 Query: 613 GVSNFNSKQLERLLXHAXVKPVVNXVECHPYLNXKRLKEFCXXRGVXIXXYSP 771 GVSN++ L++LL A + P N VE HP+L L ++C +G+ YSP Sbjct: 190 GVSNWSIAFLDKLLAKAKIVPAANQVELHPFLPQHELVKYCHDKGILPQAYSP 242 Score = 57.2 bits (132), Expect = 5e-07 Identities = 41/113 (36%), Positives = 57/113 (50%), Gaps = 27/113 (23%) Frame = +3 Query: 180 PXFGLGTWKSKPGEVTQAVKDAID-----------------IGYRHI----------DCA 278 P GLGTW+S PGEV +AV+ AI +GY + D A Sbjct: 23 PVIGLGTWQSAPGEVAKAVESAIKAGYRHIVSMLTSLLTLTLGYVALHPLYIPFLAKDAA 82 Query: 279 YVYGNEKEVGEAITSKIKEGVVTREDLFITSKLWNTFHRPDLVRGALQETLEQ 437 ++YGNE EVG+ I K V R +LF+T+K+W T+HR L E+L++ Sbjct: 83 WIYGNENEVGQGI----KASGVPRSELFVTTKIWCTYHRQP--EACLDESLQR 129 >UniRef50_Q9ZBW7 Cluster: Putative oxidoreductase; n=2; Actinomycetales|Rep: Putative oxidoreductase - Streptomyces coelicolor Length = 277 Score = 78.6 bits (185), Expect = 2e-13 Identities = 45/111 (40%), Positives = 58/111 (52%) Frame = +1 Query: 439 LNFQYLDLYLIHWPQAYKEDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGV 618 L +YLDLYLIHWP KE YVDT+KA E L+ +G V++IGV Sbjct: 99 LGLEYLDLYLIHWPMPAKER------------------YVDTYKAFEKLLADGRVRAIGV 140 Query: 619 SNFNSKQLERLLXHAXVKPVVNXVECHPYLNXKRLKEFCXXRGVXIXXYSP 771 SNF + LERL V P VN +E HP+L +E +G+ +SP Sbjct: 141 SNFLPEHLERLTAETSVIPAVNQIELHPHLQQHAAREVHAEQGIATEAWSP 191 Score = 63.7 bits (148), Expect = 6e-09 Identities = 34/92 (36%), Positives = 48/92 (52%) Frame = +3 Query: 180 PXFGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIKEGVVTREDL 359 P G G W+ + AV A++ GYR ID A +YGNE+ G AI + + REDL Sbjct: 17 PQLGFGVWQVPDDDAQTAVALALEAGYRSIDTAAIYGNEEGTGRAIAA----SGLAREDL 72 Query: 360 FITSKLWNTFHRPDLVRGALQETLEQSELSVL 455 F+T+KLWN+ D A ++ + L L Sbjct: 73 FVTTKLWNSDQGYDSTLRAFDTSMAKLGLEYL 104 >UniRef50_Q5HR31 Cluster: Oxidoreductase, aldo/keto reductase family; n=3; Staphylococcus|Rep: Oxidoreductase, aldo/keto reductase family - Staphylococcus epidermidis (strain ATCC 35984 / RP62A) Length = 279 Score = 78.6 bits (185), Expect = 2e-13 Identities = 39/113 (34%), Positives = 61/113 (53%) Frame = +1 Query: 433 NNLNFQYLDLYLIHWPQAYKEDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSI 612 +NL YLDL+LIHWP +D Y++++KA+E L +EG +K+I Sbjct: 95 DNLGLDYLDLFLIHWPCE------------------NDQLYIESYKALEHLYEEGKIKAI 136 Query: 613 GVSNFNSKQLERLLXHAXVKPVVNXVECHPYLNXKRLKEFCXXRGVXIXXYSP 771 GV NF LE+L+ + P VN +E HPY N + +++FC + + + P Sbjct: 137 GVCNFKIHHLEKLMKETKITPQVNQIELHPYFNQQDVQDFCDEHDIKVTAWMP 189 Score = 70.5 bits (165), Expect = 5e-11 Identities = 37/92 (40%), Positives = 51/92 (55%) Frame = +3 Query: 180 PXFGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIKEGVVTREDL 359 P GLG +K ++ + V+ A+D GYR D AY YGNEK +G A +K V R++L Sbjct: 15 PAVGLGVYKIADEQMEEVVRTALDAGYRAFDTAYFYGNEKALGSA----LKHSNVERDEL 70 Query: 360 FITSKLWNTFHRPDLVRGALQETLEQSELSVL 455 FITSKLWN + D ++L+ L L Sbjct: 71 FITSKLWNDYQGYDQTIEYFNKSLDNLGLDYL 102 >UniRef50_A6WDZ5 Cluster: Aldo/keto reductase; n=5; Bacteria|Rep: Aldo/keto reductase - Kineococcus radiotolerans SRS30216 Length = 343 Score = 78.6 bits (185), Expect = 2e-13 Identities = 41/98 (41%), Positives = 56/98 (57%), Gaps = 3/98 (3%) Frame = +3 Query: 180 PXFGLGTWKS---KPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIKEGVVTR 350 P G+GT+ S P EV AV A+ GYR +DCA VYGNE +VGEA+ + G V R Sbjct: 25 PAIGIGTFGSDRYSPAEVAAAVAGAVAAGYRLVDCAAVYGNEAQVGEALAGAVAGG-VDR 83 Query: 351 EDLFITSKLWNTFHRPDLVRGALQETLEQSELSVLGSV 464 ++LF+ SK+WN H P ++ +L L L +V Sbjct: 84 DELFVVSKVWNDAHAPADAVASVHRSLRDLRLDHLDAV 121 Score = 64.5 bits (150), Expect = 3e-09 Identities = 36/117 (30%), Positives = 52/117 (44%), Gaps = 1/117 (0%) Frame = +1 Query: 424 RPWNNLNFQYLDLYLIHWPQAYKEDGSLFPTDQSGKIQFSDVD-YVDTWKAMEPLVKEGL 600 R +L +LD +HWP + + + D D Y+ W A+E LV GL Sbjct: 108 RSLRDLRLDHLDAVFVHWPFPNHHPPMADTDARDPRARPYDHDAYLALWGALEGLVDSGL 167 Query: 601 VKSIGVSNFNSKQLERLLXHAXVKPVVNXVECHPYLNXKRLKEFCXXRGVXIXXYSP 771 V+ +G SN +L+ LL A + P +N +E HP L C G+ YSP Sbjct: 168 VRHLGTSNTTVAKLDLLLRDARIPPALNEMELHPCFQQPELFAHCVRHGIQPVGYSP 224 >UniRef50_Q6WGK4 Cluster: Aldose reductase; n=1; Pristionchus pacificus|Rep: Aldose reductase - Pristionchus pacificus Length = 293 Score = 78.6 bits (185), Expect = 2e-13 Identities = 40/111 (36%), Positives = 57/111 (51%) Frame = +1 Query: 436 NLNFQYLDLYLIHWPQAYKEDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIG 615 +L Y+DL LIHWP S ++ +F YV+ +E L+ EG ++SIG Sbjct: 103 DLQTPYIDLVLIHWPGT-----SRLKSNHKDNAKFRAETYVE----LETLMDEGKIRSIG 153 Query: 616 VSNFNSKQLERLLXHAXVKPVVNXVECHPYLNXKRLKEFCXXRGVXIXXYS 768 VSN+ K LE LL + P +N ECHP+ L E+C +G+ YS Sbjct: 154 VSNYEIKHLETLLAECRILPAINQCECHPHFRNSELAEYCKEKGIHFQAYS 204 Score = 52.8 bits (121), Expect = 1e-05 Identities = 25/67 (37%), Positives = 41/67 (61%), Gaps = 1/67 (1%) Frame = +3 Query: 180 PXFGLGTWKSKPGEV-TQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIKEGVVTRED 356 P G+GT++ + V T + +A +GYR ID A +Y NE +G + +++ + RED Sbjct: 17 PMIGVGTYQVQSQSVLTDTIDEAFRLGYRFIDTAQIYRNEAILGRILPDLLEKHSLKRED 76 Query: 357 LFITSKL 377 +FITSK+ Sbjct: 77 IFITSKV 83 >UniRef50_Q88SL1 Cluster: Oxidoreductase; n=51; Lactobacillales|Rep: Oxidoreductase - Lactobacillus plantarum Length = 286 Score = 78.2 bits (184), Expect = 3e-13 Identities = 40/85 (47%), Positives = 52/85 (61%), Gaps = 1/85 (1%) Frame = +3 Query: 180 PXFGLGTWKSKPGEVT-QAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIKEGVVTRED 356 P G GTW++ G+V +V A+ GYRHID A YGNE+ VG+AI + V RED Sbjct: 20 PIVGFGTWQTPDGQVAYDSVLAALKAGYRHIDTAAAYGNEESVGKAIA----DSGVARED 75 Query: 357 LFITSKLWNTFHRPDLVRGALQETL 431 LF+T+KLWN H D + AL +L Sbjct: 76 LFVTTKLWNADHGYDAAKKALDTSL 100 Score = 54.0 bits (124), Expect = 5e-06 Identities = 35/111 (31%), Positives = 50/111 (45%) Frame = +1 Query: 439 LNFQYLDLYLIHWPQAYKEDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGV 618 L Y+DLYLIHWP + + + ++ DTW+AME ++IGV Sbjct: 103 LGLDYVDLYLIHWPNP-----------AAMRDNWEQLN-ADTWRAMEEAYTARKARAIGV 150 Query: 619 SNFNSKQLERLLXHAXVKPVVNXVECHPYLNXKRLKEFCXXRGVXIXXYSP 771 SNF K L+ LL A V P VN + +P + + + YSP Sbjct: 151 SNFRPKHLDALLKTAKVVPAVNQIFLNPSDMEDEVVAYNRKHDILSEAYSP 201 >UniRef50_Q83N50 Cluster: 2,5-diketo-D-gluconic acid reductase; n=2; Tropheryma whipplei|Rep: 2,5-diketo-D-gluconic acid reductase - Tropheryma whipplei (strain Twist) (Whipple's bacillus) Length = 283 Score = 78.2 bits (184), Expect = 3e-13 Identities = 35/69 (50%), Positives = 48/69 (69%) Frame = +3 Query: 180 PXFGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIKEGVVTREDL 359 P FGLGT++ P E + V+ AI++GYRHID A +Y NE+EVG AI S + RE+ Sbjct: 21 PQFGLGTYELPPNEASSVVQSAIELGYRHIDTASLYANEREVGRAIAS----SGIKREEF 76 Query: 360 FITSKLWNT 386 F+T+KLWN+ Sbjct: 77 FVTTKLWNS 85 Score = 62.1 bits (144), Expect = 2e-08 Identities = 35/111 (31%), Positives = 55/111 (49%) Frame = +1 Query: 439 LNFQYLDLYLIHWPQAYKEDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGV 618 L+ Y+DLYLIHWP P++ Y++ W+ + L + G KS+GV Sbjct: 101 LSLDYVDLYLIHWPCP--------PSEL----------YINVWEVLLELKESGRAKSVGV 142 Query: 619 SNFNSKQLERLLXHAXVKPVVNXVECHPYLNXKRLKEFCXXRGVXIXXYSP 771 SNF S+ ++++ P VN +E HP+L + L C G+ I + P Sbjct: 143 SNFLSEHIDKIKEAGFPLPSVNQIELHPWLQQRELVLSCRNDGIQIESWGP 193 >UniRef50_Q5TNP1 Cluster: ENSANGP00000029046; n=2; Culicidae|Rep: ENSANGP00000029046 - Anopheles gambiae str. PEST Length = 331 Score = 78.2 bits (184), Expect = 3e-13 Identities = 44/118 (37%), Positives = 59/118 (50%), Gaps = 2/118 (1%) Frame = +1 Query: 421 RRPWNNLNFQYLDLYLIHWPQAYKEDGSLFPTDQSGKIQFSDVDY-VDTWKAMEPLVKEG 597 R+ NL YLDLYLIHWP + G +V Y +W A+ L +EG Sbjct: 125 RKSLANLQTDYLDLYLIHWPGVSGKCGRWKWLFGMQVTHPDNVKYRAASWNALSKLEREG 184 Query: 598 LVKSIGVSNFNSKQLERLLXHA-XVKPVVNXVECHPYLNXKRLKEFCXXRGVXIXXYS 768 ++SIGVSN+ K L+ +L + P VN VE HPY L E+C G+ + YS Sbjct: 185 CLRSIGVSNYTVKHLKEMLADCKGIVPAVNQVEWHPYYYQPELLEYCRQHGIFLQAYS 242 Score = 58.4 bits (135), Expect = 2e-07 Identities = 30/67 (44%), Positives = 43/67 (64%), Gaps = 1/67 (1%) Frame = +3 Query: 180 PXFGLGTWKSKPGEVTQAVKD-AIDIGYRHIDCAYVYGNEKEVGEAITSKIKEGVVTRED 356 P G GT++ E+ V D A++ GYRHID A VY NE+ +G A+ + + + + RED Sbjct: 43 PLAGFGTYQIHGQELIYQVLDYALEAGYRHIDTAVVYRNEEYIGTALKTLLPKYNLKRED 102 Query: 357 LFITSKL 377 +FITSKL Sbjct: 103 IFITSKL 109 >UniRef50_A7RRF6 Cluster: Predicted protein; n=2; Nematostella vectensis|Rep: Predicted protein - Nematostella vectensis Length = 275 Score = 78.2 bits (184), Expect = 3e-13 Identities = 35/72 (48%), Positives = 45/72 (62%) Frame = +1 Query: 556 VDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLXHAXVKPVVNXVECHPYLNXKRLKEFC 735 V +W+AM L +GL +SIGVSNFN LE L H+ + PVVN +E HPYL + L +FC Sbjct: 117 VGSWEAMAELQGKGLTRSIGVSNFNIHHLEALQKHSVIPPVVNQIEVHPYLQMEELVDFC 176 Query: 736 XXRGVXIXXYSP 771 + I YSP Sbjct: 177 RKHSIAIQAYSP 188 Score = 55.6 bits (128), Expect = 2e-06 Identities = 29/71 (40%), Positives = 42/71 (59%) Frame = +3 Query: 180 PXFGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIKEGVVTREDL 359 P FGLG + QAV A++ GYR ID A Y NEK VGEA ++E V R ++ Sbjct: 16 PRFGLGLYDLDEKHTKQAVLWALENGYRMIDTAASYNNEKRVGEA----LRESAVPRSEV 71 Query: 360 FITSKLWNTFH 392 ++ +K+++T H Sbjct: 72 YLVTKVYHTDH 82 >UniRef50_A3LTU8 Cluster: D-arabinose dehydrogenase; n=5; Saccharomycetales|Rep: D-arabinose dehydrogenase - Pichia stipitis (Yeast) Length = 326 Score = 78.2 bits (184), Expect = 3e-13 Identities = 45/122 (36%), Positives = 67/122 (54%), Gaps = 10/122 (8%) Frame = +1 Query: 436 NLNFQYLDLYLIHWPQAYKEDGSLFPT---DQSGKIQFSD-----VDYVDTWKAMEPLVK 591 +L Y+DL+L HWP D + P D+ GK+ + D + Y+D + ++E ++ Sbjct: 103 DLGLDYVDLFLQHWPVVLHGDENGLPPQPRDKDGKLIYDDDPVSGIKYIDAYHSLEDIMD 162 Query: 592 E-GLVKSIGVSNFNSKQLERLLXHAXV-KPVVNXVECHPYLNXKRLKEFCXXRGVXIXXY 765 VKSIGVSN++ +L +LL KPVVN +E HP L + L ++C GV I Y Sbjct: 163 NTSKVKSIGVSNYSIPKLRKLLAAVRKHKPVVNQIEYHPLLPQQDLVKYCYDNGVHISAY 222 Query: 766 SP 771 SP Sbjct: 223 SP 224 Score = 75.8 bits (178), Expect = 1e-12 Identities = 35/73 (47%), Positives = 49/73 (67%), Gaps = 1/73 (1%) Frame = +3 Query: 180 PXFGLGTWKSK-PGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIKEGVVTRED 356 P GLGT + P E+ + V A+ GYRHID A+ YG E+ +G+A+ +EG+V RED Sbjct: 19 PALGLGTVPPEDPHELKEQVITAVKAGYRHIDTAWYYGTEEYIGQALKQLFEEGIVKRED 78 Query: 357 LFITSKLWNTFHR 395 LFIT+K+W +F R Sbjct: 79 LFITTKVWPSFWR 91 >UniRef50_UPI00006CD296 Cluster: oxidoreductase, aldo/keto reductase family protein; n=1; Tetrahymena thermophila SB210|Rep: oxidoreductase, aldo/keto reductase family protein - Tetrahymena thermophila SB210 Length = 295 Score = 77.8 bits (183), Expect = 3e-13 Identities = 42/117 (35%), Positives = 61/117 (52%) Frame = +1 Query: 421 RRPWNNLNFQYLDLYLIHWPQAYKEDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGL 600 R+ NL Y+DLYL+H+ S PTDQ + + W E LV++GL Sbjct: 96 RQSLQNLQTNYIDLYLLHY-------ASSPPTDQ---FELTHKPVFQVWAEFEELVQKGL 145 Query: 601 VKSIGVSNFNSKQLERLLXHAXVKPVVNXVECHPYLNXKRLKEFCXXRGVXIXXYSP 771 +++IG+SNFN + L L + +KPVVN +E + Y RL EFC + + Y P Sbjct: 146 IRNIGISNFNVQMLLDLYSYCKIKPVVNQIEVNVYCQQPRLLEFCKKLNLHVTAYCP 202 Score = 73.7 bits (173), Expect = 6e-12 Identities = 38/84 (45%), Positives = 55/84 (65%), Gaps = 3/84 (3%) Frame = +3 Query: 180 PXFGLGTWKS-KPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIKEGVVTRED 356 P FGLGT+K E+ ++ A+D+GYRHID A +Y NEK++G+A+ KEG RED Sbjct: 17 PVFGLGTYKVVSKEEMVTFLRTALDLGYRHIDTAIMYENEKQIGDALQEIYKEGKYKRED 76 Query: 357 LFITSKLWNTFHR--PDLVRGALQ 422 LF+ +KL++ + D VR +LQ Sbjct: 77 LFLVTKLFSNKNTKVEDQVRQSLQ 100 >UniRef50_Q5FK98 Cluster: Oxidoreductase; n=8; Lactobacillales|Rep: Oxidoreductase - Lactobacillus acidophilus Length = 285 Score = 77.4 bits (182), Expect = 5e-13 Identities = 41/93 (44%), Positives = 57/93 (61%), Gaps = 1/93 (1%) Frame = +3 Query: 180 PXFGLGTWKSKPGEVTQ-AVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIKEGVVTRED 356 P G GTW++ GEV + +V A++ GYRHID A YGNE VG AI K G + R + Sbjct: 19 PIIGFGTWQTPDGEVAEESVLAALNCGYRHIDTASAYGNEDSVGRAIQ---KSG-INRHE 74 Query: 357 LFITSKLWNTFHRPDLVRGALQETLEQSELSVL 455 LFIT+KLWN+ H + + A+ ++L +L L Sbjct: 75 LFITTKLWNSDHGYEKTKKAIDQSLLDLKLDYL 107 Score = 63.7 bits (148), Expect = 6e-09 Identities = 32/89 (35%), Positives = 52/89 (58%) Frame = +1 Query: 436 NLNFQYLDLYLIHWPQAYKEDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIG 615 +L YLD+YLIHWP S + +++++ ++W+AME V+ G +++IG Sbjct: 101 DLKLDYLDMYLIHWPNP-----------SSMRDHWAEIN-AESWRAMEEAVRAGKIRAIG 148 Query: 616 VSNFNSKQLERLLXHAXVKPVVNXVECHP 702 VSNF L+ L+ A +KPVVN + +P Sbjct: 149 VSNFRKHHLDALMETAEIKPVVNQIFLNP 177 >UniRef50_Q568D7 Cluster: Zgc:110366; n=7; Euteleostomi|Rep: Zgc:110366 - Danio rerio (Zebrafish) (Brachydanio rerio) Length = 289 Score = 77.0 bits (181), Expect = 6e-13 Identities = 43/118 (36%), Positives = 58/118 (49%) Frame = +1 Query: 418 CRRPWNNLNFQYLDLYLIHWPQAYKEDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEG 597 CR L YLDLYL+HWP S+ P S +++ ++TW+A+E L EG Sbjct: 100 CRDSRARLGVDYLDLYLMHWPD------SMVPGRSSQEVR------LETWRALEELYDEG 147 Query: 598 LVKSIGVSNFNSKQLERLLXHAXVKPVVNXVECHPYLNXKRLKEFCXXRGVXIXXYSP 771 L ++IGVSNF L L + P VN VE HP+ +L E C + Y P Sbjct: 148 LCRAIGVSNFLIPHLNELKDSGGIVPHVNQVEFHPFQQPMKLVEHCRKENIVFEGYCP 205 Score = 48.8 bits (111), Expect = 2e-04 Identities = 37/115 (32%), Positives = 59/115 (51%), Gaps = 5/115 (4%) Frame = +3 Query: 180 PXFGLGTWKSKPGEVTQAVKDAI-DIGYRHIDCAYVYGNEKEVGEAITSKIKEGVVTRED 356 P GLGT G +AV A+ + G RHID A YG E+ +G+A+T E V RE+ Sbjct: 25 PILGLGT-SHYGGYSHEAVLYALQECGIRHIDTAKRYGCEEALGKAVT----ESGVQREE 79 Query: 357 LFITSKLWNTFHRPDLVRGALQETLEQSELSVLGSV----PDTLAPGLQGRRLSL 509 L++T+KLW + + A +++ + + L PD++ PG + + L Sbjct: 80 LWVTTKLWPGDYGYQSTKQACRDSRARLGVDYLDLYLMHWPDSMVPGRSSQEVRL 134 >UniRef50_UPI0000DB6EE9 Cluster: PREDICTED: similar to C35D10.6; n=2; Endopterygota|Rep: PREDICTED: similar to C35D10.6 - Apis mellifera Length = 292 Score = 76.2 bits (179), Expect = 1e-12 Identities = 41/110 (37%), Positives = 57/110 (51%), Gaps = 1/110 (0%) Frame = +1 Query: 442 NFQYLDLYLIHWPQAYKEDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVS 621 N Y+DLYLIHWP A + P + TW + L K+G ++SIGVS Sbjct: 106 NTTYIDLYLIHWPGATR-----IPETSTNNPSLR----AKTWNKLVDLKKQGFIRSIGVS 156 Query: 622 NFNSKQLERLLXHA-XVKPVVNXVECHPYLNXKRLKEFCXXRGVXIXXYS 768 NF K L+ LL + + P VN VE HP+ + L ++C +G+ I YS Sbjct: 157 NFTIKHLQELLQNCKDILPAVNQVELHPHYRQEELIKYCNEKGIHIQAYS 206 Score = 54.0 bits (124), Expect = 5e-06 Identities = 26/67 (38%), Positives = 44/67 (65%), Gaps = 1/67 (1%) Frame = +3 Query: 180 PXFGLGTWKSKPGE-VTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIKEGVVTRED 356 P G GT+K + E V Q V +++++G+R ID A Y NE+++G A+ + + + + R D Sbjct: 17 PLIGFGTYKIQGRELVYQVVDESLNVGFRSIDTAVGYRNEEDIGYALKNLLPKYNLQRSD 76 Query: 357 LFITSKL 377 +FIT+KL Sbjct: 77 IFITTKL 83 >UniRef50_Q929C8 Cluster: Lin2349 protein; n=12; Listeria|Rep: Lin2349 protein - Listeria innocua Length = 294 Score = 76.2 bits (179), Expect = 1e-12 Identities = 47/116 (40%), Positives = 58/116 (50%) Frame = +1 Query: 424 RPWNNLNFQYLDLYLIHWPQAYKEDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLV 603 R NL YLDLYLIHWP A K Y D+W+AME L E L+ Sbjct: 96 RTLRNLKLDYLDLYLIHWPVAGK--------------------YRDSWRAMERLHDEKLI 135 Query: 604 KSIGVSNFNSKQLERLLXHAXVKPVVNXVECHPYLNXKRLKEFCXXRGVXIXXYSP 771 KSIGV+NF L LL A KPV+N VE HP L L+++ + + +SP Sbjct: 136 KSIGVANFKQHHLSDLLVAANEKPVLNQVETHPLLPQNDLRKYLAEQNIAHAAWSP 191 Score = 60.9 bits (141), Expect = 4e-08 Identities = 38/93 (40%), Positives = 51/93 (54%), Gaps = 1/93 (1%) Frame = +3 Query: 180 PXFGLGTWKSKPGE-VTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIKEGVVTRED 356 P GLG ++ E + AV+ AI++GYR D A VY NE VG+AI + V RE+ Sbjct: 18 PYIGLGVFQVTEQEFIAGAVEKAIEVGYRLFDTAAVYNNEAIVGQAIL----DSAVPREE 73 Query: 357 LFITSKLWNTFHRPDLVRGALQETLEQSELSVL 455 LFI+SK+WN D A + TL +L L Sbjct: 74 LFISSKVWNGDLGYDETLFAFERTLRNLKLDYL 106 >UniRef50_Q9A2X8 Cluster: Oxidoreductase, aldo/keto reductase family; n=3; Caulobacter|Rep: Oxidoreductase, aldo/keto reductase family - Caulobacter crescentus (Caulobacter vibrioides) Length = 279 Score = 75.8 bits (178), Expect = 1e-12 Identities = 38/91 (41%), Positives = 59/91 (64%), Gaps = 1/91 (1%) Frame = +3 Query: 168 EXLFPXFGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIKEGVVT 347 + L P G GTW+ + G V+ A++IGYRHID A +YGNE++VG A I+ V Sbjct: 12 DVLMPALGFGTWQLENGTAVPLVEKALEIGYRHIDTAQIYGNERDVGAA----IRNSGVK 67 Query: 348 REDLFITSKLW-NTFHRPDLVRGALQETLEQ 437 R+++F+T+K+W + F DL R A +++LE+ Sbjct: 68 RDEIFLTTKVWIDQFADGDLQRSA-EKSLEK 97 Score = 51.6 bits (118), Expect = 3e-05 Identities = 28/76 (36%), Positives = 40/76 (52%) Frame = +1 Query: 544 DVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLXHAXVKPVVNXVECHPYLNXKRL 723 +V +T KA+ + +G ++IG+SNF S QLE + + VE HPYL+ K L Sbjct: 114 EVPLAETLKALNAVRAKGWTRAIGLSNFPSAQLEEAAKLSEAPIATDQVEYHPYLSLKTL 173 Query: 724 KEFCXXRGVXIXXYSP 771 K GV I +SP Sbjct: 174 KAKADQLGVSITAWSP 189 >UniRef50_A7CWF9 Cluster: Aldehyde reductase; n=2; Bacteria|Rep: Aldehyde reductase - Opitutaceae bacterium TAV2 Length = 347 Score = 75.8 bits (178), Expect = 1e-12 Identities = 41/96 (42%), Positives = 54/96 (56%), Gaps = 4/96 (4%) Frame = +3 Query: 180 PXFGLGTWKSK---PGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIKEGV-VT 347 P G+GT+ S PGEV +V A ++GYRH DCA VY NE+E+G + + Sbjct: 28 PAIGMGTFGSDHAAPGEVAASVYAAAELGYRHFDCAAVYSNEREIGATFRRILTSNTGIR 87 Query: 348 REDLFITSKLWNTFHRPDLVRGALQETLEQSELSVL 455 REDL+ITSKLWN H V A +++L L L Sbjct: 88 REDLWITSKLWNDKHAEADVIPAFEKSLRDLGLDYL 123 Score = 75.4 bits (177), Expect = 2e-12 Identities = 38/113 (33%), Positives = 56/113 (49%), Gaps = 1/113 (0%) Frame = +1 Query: 436 NLNFQYLDLYLIHWP-QAYKEDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSI 612 +L YLDLYLIHWP + G + + +++ TW+ +E L GLV+ I Sbjct: 117 DLGLDYLDLYLIHWPFPNFHPPGCDVSSRSPDARPYIHAEFMKTWRQLETLHDRGLVRHI 176 Query: 613 GVSNFNSKQLERLLXHAXVKPVVNXVECHPYLNXKRLKEFCXXRGVXIXXYSP 771 G SN +L+ LL A V+P VN +E HP+ L ++ R + Y P Sbjct: 177 GTSNMTIAKLQLLLRDARVRPAVNEMELHPHFQQPALFDYVRVRNIVPVGYCP 229 >UniRef50_Q0DHN0 Cluster: Os05g0456200 protein; n=2; Oryza sativa (japonica cultivar-group)|Rep: Os05g0456200 protein - Oryza sativa subsp. japonica (Rice) Length = 229 Score = 75.8 bits (178), Expect = 1e-12 Identities = 35/74 (47%), Positives = 46/74 (62%) Frame = +1 Query: 550 DYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLXHAXVKPVVNXVECHPYLNXKRLKE 729 D TW+AME L G ++IGVSNF+ K+LE LL A V P VN VECHP +L++ Sbjct: 76 DIPATWQAMEKLYDSGKARAIGVSNFSCKKLEDLLNVARVPPAVNQVECHPVWQQGKLRK 135 Query: 730 FCXXRGVXIXXYSP 771 C +GV + Y+P Sbjct: 136 LCQSKGVHLSAYAP 149 Score = 63.3 bits (147), Expect = 8e-09 Identities = 25/49 (51%), Positives = 34/49 (69%) Frame = +3 Query: 180 PXFGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSK 326 P GLGTW+ PG V A++ A+ +GYRHIDC+ YGN+KEV + +K Sbjct: 14 PSVGLGTWQISPGAVQDAIRAAVQVGYRHIDCSPQYGNQKEVHGPVRAK 62 >UniRef50_Q968S3 Cluster: Aldoketoreductase-like protein; n=1; Orconectes limosus|Rep: Aldoketoreductase-like protein - Orconectes limosus (Spinycheek crayfish) Length = 336 Score = 75.8 bits (178), Expect = 1e-12 Identities = 37/114 (32%), Positives = 61/114 (53%), Gaps = 1/114 (0%) Frame = +1 Query: 433 NNLNFQYLDLYLIHWPQAYKE-DGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKS 609 +NL Y+DLYL+H+P + D D+ +D+ + W+AME + G K+ Sbjct: 113 DNLRLPYVDLYLVHYPCGILDTDRERLSADEVTVDPTTDIHAI--WRAMEAQLAAGKTKN 170 Query: 610 IGVSNFNSKQLERLLXHAXVKPVVNXVECHPYLNXKRLKEFCXXRGVXIXXYSP 771 IG+SNFN+ Q++R++ V+P V VE H Y+ L+ FC + + + P Sbjct: 171 IGLSNFNADQVQRIIKGCQVRPAVLQVEVHVYMQQGALRAFCAQHDIVVCAFCP 224 Score = 63.3 bits (147), Expect = 8e-09 Identities = 38/95 (40%), Positives = 51/95 (53%), Gaps = 6/95 (6%) Frame = +3 Query: 180 PXFGLGTW------KSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIKEGV 341 P GLGT K VT ++ A++ GYRH D A YGNE +G+ + I EG Sbjct: 23 PVMGLGTGSLGRNGKMSEEAVTAVLETALECGYRHFDSAAYYGNEAIIGQVLRRWISEGK 82 Query: 342 VTREDLFITSKLWNTFHRPDLVRGALQETLEQSEL 446 V RE+LFIT+KL +R V LQ++L+ L Sbjct: 83 VKREELFITTKLPTRGNREKDVARFLQKSLDNLRL 117 >UniRef50_Q5FT75 Cluster: Putative 2,5-diketo-D-gluconic acid reductase; n=1; Gluconobacter oxydans|Rep: Putative 2,5-diketo-D-gluconic acid reductase - Gluconobacter oxydans (Gluconobacter suboxydans) Length = 279 Score = 75.4 bits (177), Expect = 2e-12 Identities = 43/106 (40%), Positives = 54/106 (50%) Frame = +1 Query: 454 LDLYLIHWPQAYKEDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNS 633 LDLYLIHWP + YV+TWKA+ L K G VKSIGVSNF S Sbjct: 106 LDLYLIHWPMP------------------AQGQYVETWKALVELKKSGRVKSIGVSNFES 147 Query: 634 KQLERLLXHAXVKPVVNXVECHPYLNXKRLKEFCXXRGVXIXXYSP 771 + LER++ V PVVN +E HP + L+EF + + P Sbjct: 148 EHLERIMDATGVVPVVNQIELHPDFQQRALREFHEKHNIRTESWRP 193 Score = 62.1 bits (144), Expect = 2e-08 Identities = 30/83 (36%), Positives = 47/83 (56%) Frame = +3 Query: 180 PXFGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIKEGVVTREDL 359 P GLG W++ P E + VK+A+ +GYR +D A +Y NE+ VG +G+ ++ Sbjct: 23 PQIGLGVWETPPDETAEVVKEAVKLGYRSVDTARLYKNEEGVG--------KGLEDHPEI 74 Query: 360 FITSKLWNTFHRPDLVRGALQET 428 F+T+KLWN D A +E+ Sbjct: 75 FLTTKLWNDEQGYDSTLRAYEES 97 >UniRef50_A6LZ55 Cluster: 2,5-didehydrogluconate reductase; n=1; Clostridium beijerinckii NCIMB 8052|Rep: 2,5-didehydrogluconate reductase - Clostridium beijerinckii NCIMB 8052 Length = 289 Score = 75.4 bits (177), Expect = 2e-12 Identities = 39/93 (41%), Positives = 57/93 (61%), Gaps = 1/93 (1%) Frame = +3 Query: 180 PXFGLGTWKSKPGEVTQ-AVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIKEGVVTRED 356 P G G +K GE + AV +AI IGYRH D A +YGNEK++G A I++ + RE+ Sbjct: 17 PQVGFGVYKLNKGEDFETAVGEAIKIGYRHFDTAKIYGNEKDLGLA----IEKSQIPREE 72 Query: 357 LFITSKLWNTFHRPDLVRGALQETLEQSELSVL 455 FITSK+WNT H + + A ++T ++ + L Sbjct: 73 FFITSKVWNTDHGYEATKKAFEQTCKKLNVEYL 105 Score = 66.1 bits (154), Expect = 1e-09 Identities = 35/111 (31%), Positives = 56/111 (50%) Frame = +1 Query: 439 LNFQYLDLYLIHWPQAYKEDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGV 618 LN +YLD+YLIH+ +Y Y++TW AME L +G +K IGV Sbjct: 100 LNVEYLDMYLIHFASSY---------------------YLETWHAMEELYLQGKIKVIGV 138 Query: 619 SNFNSKQLERLLXHAXVKPVVNXVECHPYLNXKRLKEFCXXRGVXIXXYSP 771 +NF + LE L+ H+ + P++N +E HP L ++ + ++P Sbjct: 139 ANFQIQHLEELMKHSRITPMINQIETHPEFPQNELHQYLTKHKILHEAWAP 189 >UniRef50_A0JX62 Cluster: 2,5-didehydrogluconate reductase; n=9; Bacteria|Rep: 2,5-didehydrogluconate reductase - Arthrobacter sp. (strain FB24) Length = 291 Score = 75.4 bits (177), Expect = 2e-12 Identities = 43/113 (38%), Positives = 61/113 (53%) Frame = +1 Query: 433 NNLNFQYLDLYLIHWPQAYKEDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSI 612 +NL +Y+DLYLIHWP A + LF ++++AME L +EG +++I Sbjct: 113 SNLGMEYVDLYLIHWPCARR---GLF---------------TESYRAMETLYREGRIRAI 154 Query: 613 GVSNFNSKQLERLLXHAXVKPVVNXVECHPYLNXKRLKEFCXXRGVXIXXYSP 771 GVSNF LE LL A V P VN +E HP+L L++ G+ +SP Sbjct: 155 GVSNFQPAHLEHLLETAEVVPAVNQIELHPWLQQDELRQLHDRLGIRTEAWSP 207 Score = 55.2 bits (127), Expect = 2e-06 Identities = 34/99 (34%), Positives = 47/99 (47%), Gaps = 13/99 (13%) Frame = +3 Query: 174 LFPXFGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAI------------ 317 L G G +K P + V A++ GYRH D A +YGNE VG+AI Sbjct: 14 LIDQLGFGLYKVPPADAAGLVTMALEAGYRHFDTAAMYGNETGVGKAIGALAGFAGGGPA 73 Query: 318 -TSKIKEGVVTREDLFITSKLWNTFHRPDLVRGALQETL 431 S ++REDLF+T+K+WN H D A ++ Sbjct: 74 GGSGEAAPSLSREDLFVTTKVWNDDHGYDATMRAFDTSM 112 >UniRef50_Q013C5 Cluster: Glycerol dehydrogenase, putative; n=2; Ostreococcus|Rep: Glycerol dehydrogenase, putative - Ostreococcus tauri Length = 425 Score = 75.4 bits (177), Expect = 2e-12 Identities = 39/110 (35%), Positives = 60/110 (54%) Frame = +1 Query: 439 LNFQYLDLYLIHWPQAYKEDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGV 618 L +YLDL+ + WP +K + D G ++ +TW A+E V +G VK++GV Sbjct: 211 LGIEYLDLFSLEWPVVHKPGTT--EVDSEGSLE-------ETWAALEKCVADGRVKALGV 261 Query: 619 SNFNSKQLERLLXHAXVKPVVNXVECHPYLNXKRLKEFCXXRGVXIXXYS 768 +NF+ +ERL+ VKP VN VE HP L ++L C GV + ++ Sbjct: 262 ANFSVPAVERLMKCCKVKPAVNEVELHPLLAQRKLVGVCRRYGVTVLAHT 311 >UniRef50_Q1RFP0 Cluster: 2,5-diketo-D-gluconic acid reductase A; n=21; Bacteria|Rep: 2,5-diketo-D-gluconic acid reductase A - Escherichia coli (strain UTI89 / UPEC) Length = 294 Score = 74.9 bits (176), Expect = 2e-12 Identities = 41/91 (45%), Positives = 55/91 (60%), Gaps = 2/91 (2%) Frame = +3 Query: 180 PXFGLGTWKSKPGEVT-QAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIKEGVVTRED 356 P G G ++ +V Q+V +AI GYR ID A VYGNE VGEA+ I EG+ TRE+ Sbjct: 18 PMMGFGVFQVTDKDVCKQSVLNAIRTGYRLIDTAAVYGNEDAVGEAVREAISEGLCTREE 77 Query: 357 LFITSKLW-NTFHRPDLVRGALQETLEQSEL 446 LFITSKLW D+ ++ +L++S L Sbjct: 78 LFITSKLWVQDMLNQDIAAAGIEASLKKSGL 108 Score = 55.6 bits (128), Expect = 2e-06 Identities = 25/52 (48%), Positives = 31/52 (59%) Frame = +1 Query: 550 DYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLXHAXVKPVVNXVECHPY 705 DY W+A+E +EG +K+IGVSNF L VKP+VN VE HPY Sbjct: 122 DYFSAWRALEDAYEEGKLKAIGVSNFYPHVLANFCETVRVKPMVNQVELHPY 173 >UniRef50_A7CUW0 Cluster: 2,5-didehydrogluconate reductase; n=6; Bacteria|Rep: 2,5-didehydrogluconate reductase - Opitutaceae bacterium TAV2 Length = 334 Score = 74.5 bits (175), Expect = 3e-12 Identities = 45/117 (38%), Positives = 56/117 (47%) Frame = +1 Query: 421 RRPWNNLNFQYLDLYLIHWPQAYKEDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGL 600 R L +Y+DLYLIHWP KI YVDTWKA+ + +GL Sbjct: 147 RESLGRLQLEYVDLYLIHWPVP--------------KID----RYVDTWKALAKIKADGL 188 Query: 601 VKSIGVSNFNSKQLERLLXHAXVKPVVNXVECHPYLNXKRLKEFCXXRGVXIXXYSP 771 +SIGVSNF L+RL + PVVN VE HP L L+ F + +SP Sbjct: 189 ARSIGVSNFTPVYLQRLFDETGIVPVVNQVELHPRLQQHELRAFHAKHRIVTEAWSP 245 Score = 60.9 bits (141), Expect = 4e-08 Identities = 32/89 (35%), Positives = 51/89 (57%) Frame = +3 Query: 180 PXFGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIKEGVVTREDL 359 P GLG W+ ++ A + GYR ID A +YGNE+ VG A I+ + R++L Sbjct: 71 PQLGLGVWQMPDDGAGVPIQAAFNAGYRAIDTAPIYGNEEGVGRA----IRASGLPRKEL 126 Query: 360 FITSKLWNTFHRPDLVRGALQETLEQSEL 446 +IT+K+WN+ D A++E+L + +L Sbjct: 127 YITTKVWNSAQGYDSTLRAVRESLGRLQL 155 >UniRef50_P91021 Cluster: Putative uncharacterized protein; n=1; Caenorhabditis elegans|Rep: Putative uncharacterized protein - Caenorhabditis elegans Length = 134 Score = 74.5 bits (175), Expect = 3e-12 Identities = 40/76 (52%), Positives = 47/76 (61%) Frame = +3 Query: 180 PXFGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIKEGVVTREDL 359 P GLGTW+S +V AVK A+ GY ID A Y NE+ +G AI I EGVV REDL Sbjct: 57 PAVGLGTWQSNAEDVISAVKAAVKNGYSLIDTASGYNNEEFIGTAIKEVIAEGVVKREDL 116 Query: 360 FITSKLWNTFHRPDLV 407 FIT+K+ N F LV Sbjct: 117 FITTKVPNLFSSLRLV 132 >UniRef50_A5ZYE6 Cluster: Putative uncharacterized protein; n=1; Ruminococcus obeum ATCC 29174|Rep: Putative uncharacterized protein - Ruminococcus obeum ATCC 29174 Length = 263 Score = 74.1 bits (174), Expect = 4e-12 Identities = 41/117 (35%), Positives = 58/117 (49%) Frame = +1 Query: 421 RRPWNNLNFQYLDLYLIHWPQAYKEDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGL 600 +R + L Y+DLYLIHWP G +++TWK ME +++ G Sbjct: 79 QRSLDRLGLDYIDLYLIHWPVP----GC----------------FLNTWKDMEKILESGR 118 Query: 601 VKSIGVSNFNSKQLERLLXHAXVKPVVNXVECHPYLNXKRLKEFCXXRGVXIXXYSP 771 SIGVSNF + LE L + + P VN +ECHP K L E+C + + Y+P Sbjct: 119 ALSIGVSNFEIRHLEELRRVSGIVPAVNQIECHPLCYPKELIEYCQANDIQVQAYAP 175 Score = 60.1 bits (139), Expect = 7e-08 Identities = 38/93 (40%), Positives = 51/93 (54%), Gaps = 1/93 (1%) Frame = +3 Query: 180 PXFGLGTWKSKPG-EVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIKEGVVTRED 356 P GLG +K+ E A+ A+ GYR +D A Y NE+ VG I K GV R+D Sbjct: 2 PLLGLGLYKTTDAVEAEDAIAAAVQNGYRLLDTASAYKNEEFVGCGIA---KCGV-PRKD 57 Query: 357 LFITSKLWNTFHRPDLVRGALQETLEQSELSVL 455 LFIT+K+WN R V GA Q +L++ L + Sbjct: 58 LFITTKIWNNAQRLGDVEGAFQRSLDRLGLDYI 90 >UniRef50_Q14LU6 Cluster: Putative aldo/keto reductase oxidoreductase protein; n=1; Spiroplasma citri|Rep: Putative aldo/keto reductase oxidoreductase protein - Spiroplasma citri Length = 138 Score = 73.7 bits (173), Expect = 6e-12 Identities = 40/83 (48%), Positives = 55/83 (66%), Gaps = 1/83 (1%) Frame = +3 Query: 180 PXFGLGTWK-SKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIKEGVVTRED 356 P GLGT+K + EV QA+ A+ GYRHID A +YGNE+ +G+A IK+ V R++ Sbjct: 17 PLIGLGTYKMTDEHEVYQAIITALQNGYRHIDTAQIYGNEELIGKA----IKDSGVPRKE 72 Query: 357 LFITSKLWNTFHRPDLVRGALQE 425 +F+TSK+WN H+ D ALQE Sbjct: 73 IFLTSKIWNANHKYD---AALQE 92 >UniRef50_Q54NR2 Cluster: Aldo-keto reductase; n=3; Dictyostelium discoideum AX4|Rep: Aldo-keto reductase - Dictyostelium discoideum AX4 Length = 305 Score = 73.7 bits (173), Expect = 6e-12 Identities = 44/111 (39%), Positives = 56/111 (50%), Gaps = 2/111 (1%) Frame = +1 Query: 439 LNFQYLDLYLIHWPQAYKEDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGV 618 L YLD YLIHWP DGS D IQ + TW+A+E L ++ V+SIGV Sbjct: 118 LQLDYLDCYLIHWPGVKGLDGS----DSGNSIQRAQ-----TWRALEKLYQDKKVRSIGV 168 Query: 619 SNFNSKQLERLL--XHAXVKPVVNXVECHPYLNXKRLKEFCXXRGVXIXXY 765 SN+ L LL + +KP +N VE HP K L EFC + + Y Sbjct: 169 SNYTINHLTELLSSPNLQIKPAINQVEFHPLNFQKDLLEFCKNNKIILESY 219 Score = 49.6 bits (113), Expect = 1e-04 Identities = 26/71 (36%), Positives = 42/71 (59%), Gaps = 6/71 (8%) Frame = +3 Query: 180 PXFGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKI--KEGV---- 341 P G+GT+K ++ +K ++ GYR ID A +Y NE+ +G+ + + +G+ Sbjct: 28 PMLGIGTFKLN--DIENIIKVGLENGYRRIDTASMYNNEERIGKVLNEMVTKNDGLDGKK 85 Query: 342 VTREDLFITSK 374 + REDLFITSK Sbjct: 86 IKREDLFITSK 96 >UniRef50_Q4Q5N9 Cluster: Prostaglandin f synthase, putative; n=7; cellular organisms|Rep: Prostaglandin f synthase, putative - Leishmania major Length = 279 Score = 73.3 bits (172), Expect = 7e-12 Identities = 34/83 (40%), Positives = 51/83 (61%) Frame = +3 Query: 180 PXFGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIKEGVVTREDL 359 P G+GTW++K G +K A++ GYRH+D A+ Y NEK VG+ I+ E V R D+ Sbjct: 17 PQLGIGTWEAKDGNEVVNIKWAVNAGYRHVDTAHYYKNEKGVGQGIS----ECGVPRSDI 72 Query: 360 FITSKLWNTFHRPDLVRGALQET 428 F+T+KLWN H + A +++ Sbjct: 73 FVTTKLWNYDHGYESALAAFEQS 95 Score = 73.3 bits (172), Expect = 7e-12 Identities = 38/111 (34%), Positives = 57/111 (51%) Frame = +1 Query: 439 LNFQYLDLYLIHWPQAYKEDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGV 618 L +Y+DLYLIHWP + Y++TW+A E L + V++IGV Sbjct: 99 LGVEYVDLYLIHWPGPNRS-------------------YIETWRAFEKLYEMKKVRAIGV 139 Query: 619 SNFNSKQLERLLXHAXVKPVVNXVECHPYLNXKRLKEFCXXRGVXIXXYSP 771 SNF L+ LL + V P+VN VE HP+ K L+ +C + + + + P Sbjct: 140 SNFEPHHLDDLLANCTVPPMVNQVEMHPHFQQKALRAYCAEKNIAVTAWRP 190 >UniRef50_Q5V6N9 Cluster: Alcohol dehydrogenase; n=2; Halobacteriaceae|Rep: Alcohol dehydrogenase - Haloarcula marismortui (Halobacterium marismortui) Length = 667 Score = 73.3 bits (172), Expect = 7e-12 Identities = 40/133 (30%), Positives = 61/133 (45%), Gaps = 15/133 (11%) Frame = +1 Query: 418 CRRPWNNLNFQYLDLYLIHWPQAYKEDGSL---------------FPTDQSGKIQFSDVD 552 CR + L D Y +HWP+A GSL FP + G I+ V Sbjct: 458 CRSSLDELGIDAFDCYALHWPEALAHRGSLTRLAEKSVARQEALTFPKNDRGDIETDSVS 517 Query: 553 YVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLXHAXVKPVVNXVECHPYLNXKRLKEF 732 W+ +E L + G +++G+ N + QLE ++ V+P + VE HPY L E+ Sbjct: 518 LQRAWENLEALHERGWTRTLGLCNVSQTQLETVIETGTVRPALVQVERHPYQPQTDLIEY 577 Query: 733 CXXRGVXIXXYSP 771 C RG+ + +SP Sbjct: 578 CHERGIRVVAHSP 590 Score = 49.2 bits (112), Expect = 1e-04 Identities = 27/89 (30%), Positives = 45/89 (50%), Gaps = 3/89 (3%) Frame = +3 Query: 180 PXFGLGTWKSKPG---EVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIKEGVVTR 350 P G G + + G + ++ A+D GYR +D A +YGNE +G + + G R Sbjct: 379 PAIGFGCSRYRDGTYIDRADSIAAALDAGYRLLDSAELYGNEHRIGRILAA---PGAPDR 435 Query: 351 EDLFITSKLWNTFHRPDLVRGALQETLEQ 437 +FI K+W T HR + A + +L++ Sbjct: 436 RRVFILGKVWRTNHRRKHMLTACRSSLDE 464 >UniRef50_Q1DLF1 Cluster: Putative uncharacterized protein; n=1; Coccidioides immitis|Rep: Putative uncharacterized protein - Coccidioides immitis Length = 324 Score = 72.5 bits (170), Expect = 1e-11 Identities = 34/70 (48%), Positives = 44/70 (62%) Frame = +1 Query: 562 TWKAMEPLVKEGLVKSIGVSNFNSKQLERLLXHAXVKPVVNXVECHPYLNXKRLKEFCXX 741 TWKAME LV +G K IGVSNF++ +L+RLL + PVVN VE +PY K+L FC Sbjct: 145 TWKAMENLVDQGKAKLIGVSNFSTPKLKRLLSVCRIFPVVNQVELNPYFPQKQLLRFCHE 204 Query: 742 RGVXIXXYSP 771 + + Y P Sbjct: 205 HEIHVTAYGP 214 Score = 62.5 bits (145), Expect = 1e-08 Identities = 44/121 (36%), Positives = 60/121 (49%), Gaps = 6/121 (4%) Frame = +3 Query: 180 PXFGLGTWKSKP-----GEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIKEGVV 344 P GLGT++ P G V +V A+ IGYRHID A YG V I + I+ V Sbjct: 17 PARGLGTFQVDPSLYPEGSVKDSVLHALKIGYRHIDAALAYG-WGSVERGIGAAIRASGV 75 Query: 345 TREDLFITSKLWNTFHRPDLVRGALQETLEQSELSVLGSVPDTLAPGLQGRRLSLPD-RP 521 RED+F+ +KL N FH P+ V + +L+ LG VP G + PD +P Sbjct: 76 PREDVFVVTKLHNCFHAPEDVEVGMNMSLKNLG---LGYVPYAYTKGENYSTVRKPDGKP 132 Query: 522 I 524 + Sbjct: 133 V 133 >UniRef50_P70883 Cluster: AkrI; n=1; Butyrivibrio fibrisolvens|Rep: AkrI - Butyrivibrio fibrisolvens Length = 172 Score = 72.1 bits (169), Expect = 2e-11 Identities = 38/93 (40%), Positives = 52/93 (55%), Gaps = 1/93 (1%) Frame = +3 Query: 180 PXFGLGTWKSKP-GEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIKEGVVTRED 356 P FG GT+K K E +V+ A+ GYRHID A Y NEK V AI ++E RED Sbjct: 17 PMFGYGTYKIKDQNEAYNSVRLALKNGYRHIDTAAFYENEKFVANAIKDFMEESQTKRED 76 Query: 357 LFITSKLWNTFHRPDLVRGALQETLEQSELSVL 455 +F+TSK W T D A ++T+ + ++ L Sbjct: 77 IFVTSKAWKTELGYDKTLAAFEKTMNEMQMDYL 109 Score = 56.0 bits (129), Expect = 1e-06 Identities = 32/84 (38%), Positives = 44/84 (52%) Frame = +1 Query: 433 NNLNFQYLDLYLIHWPQAYKEDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSI 612 N + YLDLYL+HWP +Y D T++ TWKAM + K G VK+I Sbjct: 102 NEMQMDYLDLYLVHWPASYAFDDDWENTNRQ------------TWKAMTEIYKSGRVKAI 149 Query: 613 GVSNFNSKQLERLLXHAXVKPVVN 684 GVSNF + L+ ++ V P V+ Sbjct: 150 GVSNFLTHHLDTII-DMEVTPAVD 172 >UniRef50_O13848 Cluster: NADH/NADPH dependent indole-3-acetaldehyde reductase AKR3C2; n=1; Schizosaccharomyces pombe|Rep: NADH/NADPH dependent indole-3-acetaldehyde reductase AKR3C2 - Schizosaccharomyces pombe (Fission yeast) Length = 284 Score = 72.1 bits (169), Expect = 2e-11 Identities = 46/113 (40%), Positives = 57/113 (50%), Gaps = 2/113 (1%) Frame = +1 Query: 439 LNFQYLDLYLIHWPQAYKEDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGV 618 L YLDLYL+H P + E KI S+ WKAME + GLV S+GV Sbjct: 98 LGTDYLDLYLLHSPIPFYEK----------KIPISE-----GWKAMETALGTGLVHSVGV 142 Query: 619 SNFNSKQLERLLXHAXVKPVVNXVECHP--YLNXKRLKEFCXXRGVXIXXYSP 771 SNF LE LL + + P VN +E HP Y K L EFC +G+ + Y P Sbjct: 143 SNFRIPDLEELLKTSTITPRVNQIEFHPQVYKAAKPLVEFCQSKGIIVEGYGP 195 Score = 65.7 bits (153), Expect = 1e-09 Identities = 41/92 (44%), Positives = 57/92 (61%), Gaps = 6/92 (6%) Frame = +3 Query: 180 PXFGLGT--WKSKPGEVTQ----AVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIKEGV 341 P +G+GT +K + GE+ + +VK+A+ G+ HIDCA VYGNE+EVG A +KE Sbjct: 13 PAYGVGTALFKKEKGEINRTIVDSVKNALAAGFIHIDCAEVYGNEEEVGVA----LKEAN 68 Query: 342 VTREDLFITSKLWNTFHRPDLVRGALQETLEQ 437 V R LFITSK+ H D + AL E+L + Sbjct: 69 VPRSKLFITSKV---MHNVDNIPEALNESLRK 97 >UniRef50_Q5BLA6 Cluster: Zgc:110782; n=2; Danio rerio|Rep: Zgc:110782 - Danio rerio (Zebrafish) (Brachydanio rerio) Length = 287 Score = 71.7 bits (168), Expect = 2e-11 Identities = 41/117 (35%), Positives = 58/117 (49%) Frame = +1 Query: 418 CRRPWNNLNFQYLDLYLIHWPQAYKEDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEG 597 C R L+ +Y+DLYLIHWP +G L P D + S+ +W +E G Sbjct: 94 CLRSLEQLDCEYIDLYLIHWPGM---EG-LDPEDS----RHSEYR-AQSWATLEEFHASG 144 Query: 598 LVKSIGVSNFNSKQLERLLXHAXVKPVVNXVECHPYLNXKRLKEFCXXRGVXIXXYS 768 K+IGVSN+ +K + LL V P V +EC P L + L++ C G+ YS Sbjct: 145 QFKAIGVSNYTAKHIRELLASCRVPPAVLQIECQPKLIQRELRDLCMETGIHFQAYS 201 Score = 58.4 bits (135), Expect = 2e-07 Identities = 35/87 (40%), Positives = 50/87 (57%), Gaps = 1/87 (1%) Frame = +3 Query: 180 PXFGLGTWKSKPGE-VTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIKEGVVTRED 356 P GLGT+K + E + Q+V A+ GYR D A VYGNE +G+ + + + + RED Sbjct: 15 PLLGLGTYKLQDHEQLKQSVSCALQAGYRAFDTAAVYGNEAHLGQVLKELLPKYGLIRED 74 Query: 357 LFITSKLWNTFHRPDLVRGALQETLEQ 437 +FI SKL + H G L+ +LEQ Sbjct: 75 VFIISKLAPSDHGLRAKEGCLR-SLEQ 100 >UniRef50_Q89JN4 Cluster: Oxidoreductase; n=8; Rhizobiales|Rep: Oxidoreductase - Bradyrhizobium japonicum Length = 272 Score = 71.7 bits (168), Expect = 2e-11 Identities = 33/89 (37%), Positives = 54/89 (60%) Frame = +3 Query: 180 PXFGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIKEGVVTREDL 359 P GLGTW+ + V+ A+ +GYRHID A VY NE+EVG+ ++ V R+D+ Sbjct: 12 PAIGLGTWELSGRPCARVVEQALRLGYRHIDTAQVYDNEREVGDG----VRASGVRRDDV 67 Query: 360 FITSKLWNTFHRPDLVRGALQETLEQSEL 446 F+T+K+W P+ + +++E+L + L Sbjct: 68 FLTTKVWTNHFAPNDLERSVKESLARLRL 96 Score = 50.0 bits (114), Expect = 8e-05 Identities = 26/77 (33%), Positives = 40/77 (51%) Frame = +1 Query: 541 SDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLXHAXVKPVVNXVECHPYLNXKR 720 S V +T A+ + GL + IGVSNF +E+ + + V N VE HPYL+ + Sbjct: 109 SHVPLAETLGALSHARQMGLTRHIGVSNFTVALIEQAVALSPEPLVCNQVEFHPYLDQAK 168 Query: 721 LKEFCXXRGVXIXXYSP 771 ++ C G+ + YSP Sbjct: 169 VRAACDQHGLALVAYSP 185 >UniRef50_A6NPD6 Cluster: Putative uncharacterized protein; n=3; Bacteria|Rep: Putative uncharacterized protein - Bacteroides capillosus ATCC 29799 Length = 287 Score = 71.7 bits (168), Expect = 2e-11 Identities = 41/111 (36%), Positives = 56/111 (50%) Frame = +1 Query: 439 LNFQYLDLYLIHWPQAYKEDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGV 618 L YLDLYLIHWP+ E D+ +TW+A+E L + GLV++IGV Sbjct: 98 LGTDYLDLYLIHWPRPDLELEDWAKLDR------------ETWRALERLYESGLVRAIGV 145 Query: 619 SNFNSKQLERLLXHAXVKPVVNXVECHPYLNXKRLKEFCXXRGVXIXXYSP 771 SNF LE +L A V P+V+ +E HP FC + + +SP Sbjct: 146 SNFLPHHLEPILASANVAPMVDQLEFHPGYTQDEAVAFCQNHSILVEAWSP 196 Score = 63.3 bits (147), Expect = 8e-09 Identities = 35/86 (40%), Positives = 47/86 (54%) Frame = +3 Query: 180 PXFGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIKEGVVTREDL 359 P G GT+K+ G+ + + +AI GYRH D A YG E +G+A+ E + RED Sbjct: 17 PAVGFGTYKTGDGD-SAVLSNAIAQGYRHFDTASFYGTETALGQAVA----ESDIPREDF 71 Query: 360 FITSKLWNTFHRPDLVRGALQETLEQ 437 F+TSKLW T D A TLE+ Sbjct: 72 FLTSKLWKTEMGYDAALRAFDATLER 97 >UniRef50_Q8ZI40 Cluster: 2,5-diketo-D-gluconic acid reductase A; n=74; Bacteria|Rep: 2,5-diketo-D-gluconic acid reductase A - Yersinia pestis Length = 277 Score = 71.7 bits (168), Expect = 2e-11 Identities = 39/92 (42%), Positives = 57/92 (61%), Gaps = 1/92 (1%) Frame = +3 Query: 174 LFPXFGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIKEGVVTRE 353 L P GLG W++ E AV A+++GYR ID A +Y NE+ VG+A +K V R+ Sbjct: 14 LMPQLGLGVWQASIQETELAVSKALEVGYRSIDTAAIYKNEEGVGKA----LKAAAVARD 69 Query: 354 DLFITSKLWN-TFHRPDLVRGALQETLEQSEL 446 +LFIT+KLWN H P + AL+ +L++ +L Sbjct: 70 ELFITTKLWNDDQHNP---QQALETSLQKLQL 98 Score = 67.3 bits (157), Expect = 5e-10 Identities = 37/111 (33%), Positives = 55/111 (49%) Frame = +1 Query: 439 LNFQYLDLYLIHWPQAYKEDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGV 618 L Y+DLYLIHWP K+D YV W+ + L ++GL++SIGV Sbjct: 96 LQLDYVDLYLIHWPDP-KQD-----------------HYVSAWRELVTLKEQGLIRSIGV 137 Query: 619 SNFNSKQLERLLXHAXVKPVVNXVECHPYLNXKRLKEFCXXRGVXIXXYSP 771 NF+ L+RL+ + P VN +E HP L ++L + + +SP Sbjct: 138 CNFHIPHLQRLIDETGIAPTVNQIELHPLLQQRQLHAWNATHHIATESWSP 188 >UniRef50_Q9X0A2 Cluster: Oxidoreductase, aldo/keto reductase family; n=21; Bacteria|Rep: Oxidoreductase, aldo/keto reductase family - Thermotoga maritima Length = 286 Score = 71.3 bits (167), Expect = 3e-11 Identities = 35/92 (38%), Positives = 56/92 (60%) Frame = +3 Query: 180 PXFGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIKEGVVTREDL 359 P G G ++ P + + V +AI +GYR ID A Y NE+ VG AI I EG+V RE+L Sbjct: 15 PILGYGVFQIPPEKTEECVYEAIKVGYRLIDTAASYMNEEGVGRAIKRAIDEGIVRREEL 74 Query: 360 FITSKLWNTFHRPDLVRGALQETLEQSELSVL 455 F+T+KLW + + + A +++L++ +L + Sbjct: 75 FVTTKLWVSDVGYESTKKAFEKSLKKLQLEYI 106 Score = 62.1 bits (144), Expect = 2e-08 Identities = 39/111 (35%), Positives = 53/111 (47%) Frame = +1 Query: 439 LNFQYLDLYLIHWPQAYKEDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGV 618 L +Y+DLYLIH P F DV WKAME + K+GLV++IGV Sbjct: 101 LQLEYIDLYLIHQP-------------------FGDVHCA--WKAMEEMYKDGLVRAIGV 139 Query: 619 SNFNSKQLERLLXHAXVKPVVNXVECHPYLNXKRLKEFCXXRGVXIXXYSP 771 SNF +L L+ H + P VN +E HP+ + EF + + P Sbjct: 140 SNFYPDRLMDLMVHHEIVPAVNQIEIHPFYQRQEEIEFMRNYNIQPEAWGP 190 >UniRef50_Q7VG53 Cluster: Aldo-keto reductase; n=28; Bacteria|Rep: Aldo-keto reductase - Helicobacter hepaticus Length = 292 Score = 71.3 bits (167), Expect = 3e-11 Identities = 37/67 (55%), Positives = 45/67 (67%), Gaps = 1/67 (1%) Frame = +3 Query: 180 PXFGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAI-TSKIKEGVVTRED 356 P GLGTW+ V AV++A +GYRHID A YGNE+ VGEA+ SKIK RE+ Sbjct: 24 PKLGLGTWRIDDNVVEAAVREAFKVGYRHIDTAQAYGNERGVGEAVRKSKIK-----REE 78 Query: 357 LFITSKL 377 LFITSK+ Sbjct: 79 LFITSKI 85 Score = 59.3 bits (137), Expect = 1e-07 Identities = 36/111 (32%), Positives = 52/111 (46%) Frame = +1 Query: 439 LNFQYLDLYLIHWPQAYKEDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGV 618 + ++DL LIH PQ + F K + V+ + A+E K G V+SIGV Sbjct: 106 MKLDFIDLMLIHSPQPWNS----FRKGDYFK------ENVEVYNALEDAQKAGKVRSIGV 155 Query: 619 SNFNSKQLERLLXHAXVKPVVNXVECHPYLNXKRLKEFCXXRGVXIXXYSP 771 SNF K LE +L + KP N + CH L ++C + + YSP Sbjct: 156 SNFLQKDLENILKNCKTKPAANQILCHIGNTPFTLLDYCKKQNILAEAYSP 206 >UniRef50_Q6U5V3 Cluster: Putative uncharacterized protein; n=1; Klebsiella pneumoniae|Rep: Putative uncharacterized protein - Klebsiella pneumoniae Length = 279 Score = 71.3 bits (167), Expect = 3e-11 Identities = 40/111 (36%), Positives = 57/111 (51%) Frame = +1 Query: 439 LNFQYLDLYLIHWPQAYKEDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGV 618 L +YL+L+LIHWP K YV+TW+A L GL++SIGV Sbjct: 97 LGVEYLELFLIHWPIPAKNL------------------YVETWEASIELEASGLIRSIGV 138 Query: 619 SNFNSKQLERLLXHAXVKPVVNXVECHPYLNXKRLKEFCXXRGVXIXXYSP 771 SNF + +ERL+ V P VN +E HP+ ++++ G+ I YSP Sbjct: 139 SNFTCQHIERLIEDTGVVPAVNQLELHPHFQQCDVRDYHHEAGIAIQSYSP 189 Score = 47.2 bits (107), Expect = 6e-04 Identities = 26/66 (39%), Positives = 34/66 (51%) Frame = +3 Query: 180 PXFGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIKEGVVTREDL 359 P G G W +V ++ A+ G+RH D A Y NE VG A ++ V RE L Sbjct: 15 PRPGCGLWLIDNRDVDSLIRQALKAGFRHFDTAQAYFNEDGVGRA----LRYTEVPREQL 70 Query: 360 FITSKL 377 FITSK+ Sbjct: 71 FITSKI 76 >UniRef50_A3VRL4 Cluster: Putative uncharacterized protein; n=1; Parvularcula bermudensis HTCC2503|Rep: Putative uncharacterized protein - Parvularcula bermudensis HTCC2503 Length = 278 Score = 71.3 bits (167), Expect = 3e-11 Identities = 34/87 (39%), Positives = 54/87 (62%) Frame = +3 Query: 180 PXFGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIKEGVVTREDL 359 P G GTW+ + + + + AI+ GYRHID A +Y NEK+VGE IK+ + R++L Sbjct: 12 PRLGFGTWQLEGEDARTSTRTAIETGYRHIDGAAIYKNEKKVGEG----IKDSGIPRDEL 67 Query: 360 FITSKLWNTFHRPDLVRGALQETLEQS 440 F+T+K+WN D+ +G E +++S Sbjct: 68 FVTTKIWN----EDIQKGRHSEAVDES 90 >UniRef50_A6RMS0 Cluster: Putative uncharacterized protein; n=1; Botryotinia fuckeliana B05.10|Rep: Putative uncharacterized protein - Botryotinia fuckeliana B05.10 Length = 286 Score = 71.3 bits (167), Expect = 3e-11 Identities = 31/73 (42%), Positives = 43/73 (58%) Frame = +1 Query: 553 YVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLXHAXVKPVVNXVECHPYLNXKRLKEF 732 Y +TW+AME LV G K+IG+SNFN + +R+L A ++P VN VE HPY L F Sbjct: 119 YTETWQAMEKLVDSGKAKAIGLSNFNILKTKRILEIARIRPAVNQVEAHPYFPQHELLAF 178 Query: 733 CXXRGVXIXXYSP 771 C + + + P Sbjct: 179 CEKEHIHLMAHQP 191 Score = 57.6 bits (133), Expect = 4e-07 Identities = 42/104 (40%), Positives = 55/104 (52%), Gaps = 2/104 (1%) Frame = +3 Query: 180 PXFGLGTWKSKPG--EVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIKEGVVTRE 353 P GLGT++ G +V VK AI GYRHID A YGNE+ +G+A IKE ++R+ Sbjct: 17 PAIGLGTFQGDDGNEKVKNIVKAAIQAGYRHIDGAAAYGNEEAIGDA----IKESGISRD 72 Query: 354 DLFITSKLWNTFHRPDLVRGALQETLEQSELSVLGSVPDTLAPG 485 +L ++ W H P V AL +LE L VP PG Sbjct: 73 EL---AQPW---HEPKDVERALDLSLEALGLEY---VPHAYLPG 107 >UniRef50_Q7NB44 Cluster: ARA1; n=3; Firmicutes|Rep: ARA1 - Mycoplasma gallisepticum Length = 289 Score = 70.9 bits (166), Expect = 4e-11 Identities = 36/93 (38%), Positives = 56/93 (60%), Gaps = 1/93 (1%) Frame = +3 Query: 180 PXFGLGTWKSKPGEVT-QAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIKEGVVTRED 356 P G GT+K + G+ T +AVK A+++GYRH+DCA +Y N+ V + IK V R++ Sbjct: 23 PSIGFGTYKLEDGKQTVEAVKTALEVGYRHLDCAEIYENQLSVSQG----IKLSGVNRKE 78 Query: 357 LFITSKLWNTFHRPDLVRGALQETLEQSELSVL 455 +FITSK+WN + + A + L+ +L L Sbjct: 79 IFITSKIWNDDKGYESTKKAFHKILKDLDLEYL 111 Score = 70.1 bits (164), Expect = 7e-11 Identities = 41/112 (36%), Positives = 59/112 (52%) Frame = +1 Query: 436 NLNFQYLDLYLIHWPQAYKEDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIG 615 +L+ +YLDL LIHWP G F K + +V+ TWKAME EG +K+IG Sbjct: 105 DLDLEYLDLLLIHWPI-----GKGF------KDNWQEVN-AQTWKAMEEFYLEGKIKAIG 152 Query: 616 VSNFNSKQLERLLXHAXVKPVVNXVECHPYLNXKRLKEFCXXRGVXIXXYSP 771 +SNF +E L A + P+VN +E HP + E+C + + +SP Sbjct: 153 LSNFLVHHIEALKKSAKILPMVNQLEFHPGYLQPEIVEYCQKNNIVVQAWSP 204 >UniRef50_Q6F7K7 Cluster: 2,5-diketo-D-gluconate reductase; n=20; Bacteria|Rep: 2,5-diketo-D-gluconate reductase - Acinetobacter sp. (strain ADP1) Length = 297 Score = 70.9 bits (166), Expect = 4e-11 Identities = 40/111 (36%), Positives = 55/111 (49%) Frame = +1 Query: 439 LNFQYLDLYLIHWPQAYKEDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGV 618 + F YLDLYLIHWP Q G Y++ W+A+ K+G ++SIGV Sbjct: 116 MQFDYLDLYLIHWPNP-----------QQGL-------YIEAWQALIDAQKKGYIRSIGV 157 Query: 619 SNFNSKQLERLLXHAXVKPVVNXVECHPYLNXKRLKEFCXXRGVXIXXYSP 771 SNF K +E L V PV+N VE HPY N + + + + +SP Sbjct: 158 SNFLPKHIETLRRETGVIPVINQVELHPYFNQAEQRAYDESQQIITMAWSP 208 Score = 50.8 bits (116), Expect = 5e-05 Identities = 29/92 (31%), Positives = 47/92 (51%) Frame = +3 Query: 180 PXFGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIKEGVVTREDL 359 P G GT+ K + + A+ GYR +D A+ Y NE VG A +++ + R+++ Sbjct: 34 PALGFGTYTLKGQQGVDTMLRALGHGYRMLDSAFNYENEGAVGAA----VRQSGLLRDEI 89 Query: 360 FITSKLWNTFHRPDLVRGALQETLEQSELSVL 455 FITSKL H D ++E+L + + L Sbjct: 90 FITSKLPGRHHAYDKAMETIEESLYRMQFDYL 121 >UniRef50_Q11BF8 Cluster: Aldo/keto reductase; n=12; Bacteria|Rep: Aldo/keto reductase - Mesorhizobium sp. (strain BNC1) Length = 308 Score = 70.9 bits (166), Expect = 4e-11 Identities = 31/67 (46%), Positives = 46/67 (68%) Frame = +3 Query: 180 PXFGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIKEGVVTREDL 359 P GLG +++ P E T AV++A+ +GYRHID A YGNE+EVGE I+ + R+++ Sbjct: 30 PMIGLGVFQTPPDETTAAVEEALRLGYRHIDTAAAYGNEREVGEG----IRRAGIARDEV 85 Query: 360 FITSKLW 380 FI +K+W Sbjct: 86 FIETKIW 92 Score = 59.3 bits (137), Expect = 1e-07 Identities = 26/69 (37%), Positives = 40/69 (57%) Frame = +1 Query: 565 WKAMEPLVKEGLVKSIGVSNFNSKQLERLLXHAXVKPVVNXVECHPYLNXKRLKEFCXXR 744 ++A+E L+ +G V++IGVSNF + L RLL + P VN +E HPY + L+ Sbjct: 137 YRALEKLLADGKVRAIGVSNFMPEHLTRLLTETSIVPAVNQIEVHPYFQQRALQRLHAEH 196 Query: 745 GVXIXXYSP 771 G+ +SP Sbjct: 197 GILTQAWSP 205 >UniRef50_Q235V6 Cluster: Oxidoreductase, aldo/keto reductase family protein; n=2; Tetrahymena thermophila SB210|Rep: Oxidoreductase, aldo/keto reductase family protein - Tetrahymena thermophila SB210 Length = 332 Score = 70.9 bits (166), Expect = 4e-11 Identities = 40/117 (34%), Positives = 58/117 (49%) Frame = +1 Query: 421 RRPWNNLNFQYLDLYLIHWPQAYKEDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGL 600 ++ L Y+DLY +H+P + + K +F + W +E + GL Sbjct: 96 KKSLKELQLDYVDLYYLHFPLGFLSE----------KEEFVHLPVHVAWAQLEEAHRLGL 145 Query: 601 VKSIGVSNFNSKQLERLLXHAXVKPVVNXVECHPYLNXKRLKEFCXXRGVXIXXYSP 771 KSIGVSNFN L LL +A VKPV N VE ++ K L +FC G+ + Y+P Sbjct: 146 AKSIGVSNFNVMALADLLSYAKVKPVSNQVEVSVFIQQKNLIKFCQRFGIHVTAYAP 202 Score = 64.9 bits (151), Expect = 3e-09 Identities = 31/70 (44%), Positives = 46/70 (65%), Gaps = 1/70 (1%) Frame = +3 Query: 174 LFPXFGLGTWK-SKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIKEGVVTR 350 + P GLGT+ + E+T ++ A+D GYRHID A Y NE +GE++ + KEG +R Sbjct: 15 IMPLVGLGTYLLNSKEEMTNLLRTALDAGYRHIDTAVNYQNEAMIGESLKTIFKEGKYSR 74 Query: 351 EDLFITSKLW 380 +DLFI SK++ Sbjct: 75 KDLFIVSKVF 84 >UniRef50_Q18483 Cluster: Putative uncharacterized protein; n=2; Caenorhabditis|Rep: Putative uncharacterized protein - Caenorhabditis elegans Length = 287 Score = 70.9 bits (166), Expect = 4e-11 Identities = 39/112 (34%), Positives = 57/112 (50%) Frame = +1 Query: 433 NNLNFQYLDLYLIHWPQAYKEDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSI 612 +NL +YLDL LIHWP GS ++ + V++W M ++ EG ++S+ Sbjct: 97 SNLKVEYLDLLLIHWP------GSSLKSENPANKKLR----VESWNVMCEMMAEGKLRSV 146 Query: 613 GVSNFNSKQLERLLXHAXVKPVVNXVECHPYLNXKRLKEFCXXRGVXIXXYS 768 GVSNF LE L + V P VN VE HP+ + L ++C + YS Sbjct: 147 GVSNFEICHLEELKKDSNVVPAVNQVEYHPHFHQDDLVKYCNENNIHFQAYS 198 Score = 59.7 bits (138), Expect = 1e-07 Identities = 33/101 (32%), Positives = 54/101 (53%), Gaps = 1/101 (0%) Frame = +3 Query: 156 RSTMEXLFPXFGLGTWKSKPGEVTQAVKDA-IDIGYRHIDCAYVYGNEKEVGEAITSKIK 332 R ++ P G+GTW+ + E+ + V DA GYR ID A VY NE ++G + + Sbjct: 4 REYVKNNMPLIGIGTWQVQKEEILRQVIDAGFKEGYRFIDTAQVYNNEAKIGRILEKLLP 63 Query: 333 EGVVTREDLFITSKLWNTFHRPDLVRGALQETLEQSELSVL 455 + RED++ITSKL + R +++E+L ++ L Sbjct: 64 ANGLKREDIWITSKLAPSNAGVKKARESIEESLSNLKVEYL 104 >UniRef50_Q17568 Cluster: Putative uncharacterized protein; n=1; Caenorhabditis elegans|Rep: Putative uncharacterized protein - Caenorhabditis elegans Length = 287 Score = 70.9 bits (166), Expect = 4e-11 Identities = 36/111 (32%), Positives = 59/111 (53%) Frame = +1 Query: 439 LNFQYLDLYLIHWPQAYKEDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGV 618 L+ +YLDL L+H+P+ P D + + + DTW A+E L EG ++SIGV Sbjct: 99 LDRKYLDLVLVHYPR---------PLDTEDLNENNKMYRKDTWIALEKLHAEGKIRSIGV 149 Query: 619 SNFNSKQLERLLXHAXVKPVVNXVECHPYLNXKRLKEFCXXRGVXIXXYSP 771 SN+ +E + + ++P VN +E HP+ K L+ +C + +SP Sbjct: 150 SNYEPHHIEEMRSYITIEPQVNQIEYHPHFQRKVLRAYCNKNEILFQAFSP 200 Score = 60.9 bits (141), Expect = 4e-08 Identities = 29/87 (33%), Positives = 55/87 (63%), Gaps = 2/87 (2%) Frame = +3 Query: 180 PXFGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIKEGVVTREDL 359 P LGT+++K ++ AV +A+ +GYR D A Y NEK++G A+ + + + ED+ Sbjct: 11 PKLALGTYEAKGDQLFAAVDEALKVGYRSFDTAKYYENEKDLGLALKTLLPRHNICSEDI 70 Query: 360 FITSKL--WNTFHRPDLVRGALQETLE 434 ++TSK+ +++ + +L+R + E+LE Sbjct: 71 YLTSKVFPYSSKNAAELIRKDVNESLE 97 >UniRef50_A6QXT4 Cluster: Predicted protein; n=1; Ajellomyces capsulatus NAm1|Rep: Predicted protein - Ajellomyces capsulatus NAm1 Length = 315 Score = 70.9 bits (166), Expect = 4e-11 Identities = 36/111 (32%), Positives = 60/111 (54%) Frame = +1 Query: 439 LNFQYLDLYLIHWPQAYKEDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGV 618 L+ Y+D++L+HWP A DG D+ +V+T+K ME LV +S+GV Sbjct: 67 LDVGYIDIFLLHWPNASGPDGRWRGIDERPT-------FVETYKKMEKLVGPKC-RSLGV 118 Query: 619 SNFNSKQLERLLXHAXVKPVVNXVECHPYLNXKRLKEFCXXRGVXIXXYSP 771 + + K ++ LL VKPV+N +E HP+ +L +C +G+ + + P Sbjct: 119 CSLSQKSMDVLLKECTVKPVINQIEVHPFNPSLKLVPYCLDKGIQVISWGP 169 >UniRef50_Q4WF80 Cluster: Glycerol dehydrogenase (GCY1), putative; n=1; Aspergillus fumigatus|Rep: Glycerol dehydrogenase (GCY1), putative - Aspergillus fumigatus (Sartorya fumigata) Length = 274 Score = 70.5 bits (165), Expect = 5e-11 Identities = 36/82 (43%), Positives = 47/82 (57%) Frame = +1 Query: 550 DYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLXHAXVKPVVNXVECHPYLNXKRLKE 729 DY +TW+ ME + K G VK+IGV+N++ LE L V P VN VE HP+L LKE Sbjct: 106 DY-ETWRQMEEIYKAGKVKAIGVANWSIPYLEELKKKWTVVPAVNQVELHPFLPQHALKE 164 Query: 730 FCXXRGVXIXXYSPPRXXGXXL 795 +C G+ + YSP G L Sbjct: 165 WCDKHGILLEAYSPLGSEGAPL 186 Score = 48.8 bits (111), Expect = 2e-04 Identities = 20/34 (58%), Positives = 25/34 (73%) Frame = +3 Query: 180 PXFGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAY 281 P GLGTW+S+PG+V QAV A+ GY HID A+ Sbjct: 16 PAIGLGTWRSEPGQVRQAVSFALKNGYSHIDTAF 49 >UniRef50_Q2U219 Cluster: Aldo/keto reductase family proteins; n=6; Pezizomycotina|Rep: Aldo/keto reductase family proteins - Aspergillus oryzae Length = 294 Score = 70.5 bits (165), Expect = 5e-11 Identities = 41/111 (36%), Positives = 53/111 (47%) Frame = +1 Query: 439 LNFQYLDLYLIHWPQAYKEDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGV 618 L Y+DLYLIH P K DG L W AME + + G K+IGV Sbjct: 109 LQLNYVDLYLIHSPFFAKSDGEL----------------QQAWAAMEKVQQAGKAKAIGV 152 Query: 619 SNFNSKQLERLLXHAXVKPVVNXVECHPYLNXKRLKEFCXXRGVXIXXYSP 771 SN++ LE L A + PV+N +E HPYL + L F + + I Y P Sbjct: 153 SNYHQSHLEATLKTAVIAPVINQIEHHPYLQQEELLRFQREKDIKIASYGP 203 Score = 56.4 bits (130), Expect = 9e-07 Identities = 32/71 (45%), Positives = 45/71 (63%), Gaps = 7/71 (9%) Frame = +3 Query: 186 FGLGT-WKSKPG------EVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIKEGVV 344 +G GT W + G E+ +A+K AI +GYRH+D A VYG E E+G A IKE + Sbjct: 25 YGTGTAWYKQAGDDSVNRELVEAIKTAIRLGYRHLDGAEVYGTEAELGVA----IKESGI 80 Query: 345 TREDLFITSKL 377 RE+LF+T+K+ Sbjct: 81 PREELFVTTKV 91 >UniRef50_Q5FKI1 Cluster: Reductase-dehydrogenase; n=1; Lactobacillus acidophilus|Rep: Reductase-dehydrogenase - Lactobacillus acidophilus Length = 271 Score = 70.1 bits (164), Expect = 7e-11 Identities = 38/113 (33%), Positives = 56/113 (49%) Frame = +1 Query: 433 NNLNFQYLDLYLIHWPQAYKEDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSI 612 + +Y+DL LIH PQ + E G ++ W+AME VK G V+SI Sbjct: 96 DKFGLEYIDLLLIHSPQPWIEVNRTNDRHFKGNLE--------NWRAMEEAVKAGKVRSI 147 Query: 613 GVSNFNSKQLERLLXHAXVKPVVNXVECHPYLNXKRLKEFCXXRGVXIXXYSP 771 GVSNF + +E ++ + + P VN +E H L ++C G+ I YSP Sbjct: 148 GVSNFLQEDIENIVNNGTITPAVNQIEVHIGKVPVELMDYCKKLGIKIEAYSP 200 Score = 54.4 bits (125), Expect = 4e-06 Identities = 28/66 (42%), Positives = 38/66 (57%) Frame = +3 Query: 180 PXFGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIKEGVVTREDL 359 P LGTW EV + V+ A++IGYR D A YGNE VG+ I + + R D+ Sbjct: 16 PQIQLGTWLINNDEVNKVVRQAVNIGYRGFDTAKDYGNESGVGKGIWN----SDIERSDI 71 Query: 360 FITSKL 377 F+T+KL Sbjct: 72 FLTTKL 77 >UniRef50_Q4V008 Cluster: Oxidoreductase; n=4; Proteobacteria|Rep: Oxidoreductase - Xanthomonas campestris pv. campestris (strain 8004) Length = 267 Score = 70.1 bits (164), Expect = 7e-11 Identities = 35/86 (40%), Positives = 55/86 (63%) Frame = +3 Query: 180 PXFGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIKEGVVTREDL 359 P FGLGT++ K V +V++A+ +GYR ID A +Y NE +VG+AI + V R+ L Sbjct: 4 PAFGLGTFRLKDQVVIDSVRNALALGYRAIDTAQIYDNEAQVGQAIA----DAGVPRDQL 59 Query: 360 FITSKLWNTFHRPDLVRGALQETLEQ 437 F+T+K+W D ++ +LQE+L + Sbjct: 60 FVTTKIWVDRFSRDTLQPSLQESLRK 85 Score = 43.6 bits (98), Expect = 0.007 Identities = 32/110 (29%), Positives = 47/110 (42%), Gaps = 1/110 (0%) Frame = +1 Query: 439 LNFQYLDLYLIHWPQAYKEDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGV 618 L Y+DL LIHWP P DQ V + +A+ +GL ++IGV Sbjct: 86 LGTDYVDLTLIHWPS---------PKDQ--------VPMREYLEALADAKAQGLTRAIGV 128 Query: 619 SNFNSKQLERLLXHAXVKPVV-NXVECHPYLNXKRLKEFCXXRGVXIXXY 765 SNF + + + N +E HPYL + L F +G+ + Y Sbjct: 129 SNFTIALTRQAIEILGADAIATNQIEVHPYLQNRTLIAFLREQGIHVTSY 178 >UniRef50_A0JRJ6 Cluster: Aldo/keto reductase; n=2; Micrococcineae|Rep: Aldo/keto reductase - Arthrobacter sp. (strain FB24) Length = 281 Score = 70.1 bits (164), Expect = 7e-11 Identities = 41/111 (36%), Positives = 53/111 (47%) Frame = +1 Query: 439 LNFQYLDLYLIHWPQAYKEDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGV 618 L +++DLYLIHWP S Y + WKAME L +++IGV Sbjct: 101 LGVEFVDLYLIHWPVP------------------SQGLYTEAWKAMEKLYANSQIRAIGV 142 Query: 619 SNFNSKQLERLLXHAXVKPVVNXVECHPYLNXKRLKEFCXXRGVXIXXYSP 771 SNF + L+ LL A V P VN VE HP + L C G+ + YSP Sbjct: 143 SNFLGEHLDTLLPAADVVPAVNQVEIHPTFQQQELAAKCRELGIAVEAYSP 193 Score = 60.9 bits (141), Expect = 4e-08 Identities = 31/68 (45%), Positives = 42/68 (61%) Frame = +3 Query: 180 PXFGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIKEGVVTREDL 359 P G G ++ P E + V+DA++ GYRHID A Y NE VG AI++ + RED+ Sbjct: 21 PQLGFGVFQVPPEETQRIVEDALEAGYRHIDTAAAYRNEAGVGAAISA----SGIPREDI 76 Query: 360 FITSKLWN 383 FIT+KL N Sbjct: 77 FITTKLRN 84 >UniRef50_A7TLC4 Cluster: Putative uncharacterized protein; n=1; Vanderwaltozyma polyspora DSM 70294|Rep: Putative uncharacterized protein - Vanderwaltozyma polyspora DSM 70294 Length = 313 Score = 70.1 bits (164), Expect = 7e-11 Identities = 42/113 (37%), Positives = 57/113 (50%), Gaps = 2/113 (1%) Frame = +1 Query: 439 LNFQYLDLYLIHWPQAYKEDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGV 618 L Y+DLYLIH P F + G + V WK ME L KEG KSIGV Sbjct: 111 LGLDYVDLYLIHSP--------FFDPEFKGSLTLEKV-----WKDMETLYKEGKAKSIGV 157 Query: 619 SNFNSKQLERLLXHAXVKPVVNXVECHPYLNXKR--LKEFCXXRGVXIXXYSP 771 SNF+ K +E +L A +KP VN +E + +L + + +C + + YSP Sbjct: 158 SNFSVKNIEEILKIAGIKPQVNQIEFNAFLQNQTPGIVNYCQKNNIQLEAYSP 210 Score = 34.3 bits (75), Expect = 4.2 Identities = 25/71 (35%), Positives = 36/71 (50%), Gaps = 9/71 (12%) Frame = +3 Query: 189 GLGT-WKSKPG-------EVTQAVKDAIDI-GYRHIDCAYVYGNEKEVGEAITSKIKEGV 341 G GT W +PG E+ + +K A+ + G HID A YG E+ +A +KE Sbjct: 23 GTGTRWFKRPGSEHTFSDELVEQIKYALSLPGIIHIDAAECYGTYPELAKA----LKESS 78 Query: 342 VTREDLFITSK 374 R ++FIT K Sbjct: 79 KPRSEIFITDK 89 >UniRef50_Q03U37 Cluster: Aldo/keto reductase of diketogulonate reductase family; n=5; Lactobacillus|Rep: Aldo/keto reductase of diketogulonate reductase family - Lactobacillus brevis (strain ATCC 367 / JCM 1170) Length = 282 Score = 69.7 bits (163), Expect = 9e-11 Identities = 44/111 (39%), Positives = 55/111 (49%) Frame = +1 Query: 439 LNFQYLDLYLIHWPQAYKEDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGV 618 L YLDL LIHWP +E + DTW+A+E L +G VKSIGV Sbjct: 102 LQTDYLDLLLIHWP--VREH------------------FFDTWRALEQLKADGQVKSIGV 141 Query: 619 SNFNSKQLERLLXHAXVKPVVNXVECHPYLNXKRLKEFCXXRGVXIXXYSP 771 SN+ LE L A PVVN VE HPYLN + L ++ + +SP Sbjct: 142 SNYTIAHLELLATKAKEMPVVNQVEYHPYLNQQALADYDQEHDIVTEAWSP 192 Score = 41.1 bits (92), Expect = 0.037 Identities = 29/93 (31%), Positives = 47/93 (50%), Gaps = 1/93 (1%) Frame = +3 Query: 180 PXFGLGTWK-SKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIKEGVVTRED 356 P G GT+ + + A++ A D GYR D A +Y NE +G AI ++ + RE Sbjct: 19 PVMGFGTYLLNDQPTMNTAIQTAWDAGYRMFDTAMLYRNEDILGPAI----QQLGLPREG 74 Query: 357 LFITSKLWNTFHRPDLVRGALQETLEQSELSVL 455 LF+TSK+ D A++ +L++ + L Sbjct: 75 LFLTSKVAEIVQGYDQTMKAVEGSLKRLQTDYL 107 >UniRef50_A5VK30 Cluster: 2,5-didehydrogluconate reductase; n=2; Lactobacillus reuteri|Rep: 2,5-didehydrogluconate reductase - Lactobacillus reuteri F275 Length = 300 Score = 69.7 bits (163), Expect = 9e-11 Identities = 35/111 (31%), Positives = 59/111 (53%) Frame = +1 Query: 439 LNFQYLDLYLIHWPQAYKEDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGV 618 L Y+DL L+HWP K Y ++W+A+E + K+G K+IGV Sbjct: 109 LQTNYVDLLLLHWPVNDK--------------------YNESWRALEDIYKDGQAKAIGV 148 Query: 619 SNFNSKQLERLLXHAXVKPVVNXVECHPYLNXKRLKEFCXXRGVXIXXYSP 771 NFN +++ LL HA +KP +N +E +P ++ ++ +FC + + +SP Sbjct: 149 CNFNVERMTDLLDHAKIKPAINQIEFNPLIHQPKIVKFCRENDIQLEAWSP 199 Score = 60.9 bits (141), Expect = 4e-08 Identities = 35/89 (39%), Positives = 48/89 (53%), Gaps = 1/89 (1%) Frame = +3 Query: 174 LFPXFGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIKEGVVTRE 353 L P GLG WK+ E Q VK+AI Y ID A YGNE VG+ I K R+ Sbjct: 20 LIPQLGLGVWKASLAETQQMVKEAIMNDYVLIDTAKQYGNEAAVGQGIQDGFKATGRKRD 79 Query: 354 DLFITSKLWNTFHRP-DLVRGALQETLEQ 437 +F+T+K++N D +R A+ E L++ Sbjct: 80 SIFLTTKIFNGDQGDYDKLRQAVNEQLKK 108 >UniRef50_A5BF24 Cluster: Putative uncharacterized protein; n=1; Vitis vinifera|Rep: Putative uncharacterized protein - Vitis vinifera (Grape) Length = 212 Score = 69.7 bits (163), Expect = 9e-11 Identities = 36/83 (43%), Positives = 45/83 (54%) Frame = +1 Query: 436 NLNFQYLDLYLIHWPQAYKEDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIG 615 NL YLDLYLIHW + K P ++ + +D WKAME K L K+IG Sbjct: 82 NLQLDYLDLYLIHWSVSLKPGNYELPVNKDDHLP---IDLGSVWKAMEDFQKLSLTKAIG 138 Query: 616 VSNFNSKQLERLLXHAXVKPVVN 684 VSNF+ +LE LL A + P VN Sbjct: 139 VSNFSCNKLEELLQTASILPAVN 161 Score = 52.0 bits (119), Expect = 2e-05 Identities = 25/59 (42%), Positives = 39/59 (66%), Gaps = 2/59 (3%) Frame = +3 Query: 213 PGE-VTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIKEGVV-TREDLFITSKLWN 383 P E + ++ AI++GYRH DC Y +EK +GEAI +K G++ +R++LFIT + N Sbjct: 24 PSETMIDSILTAIELGYRHFDCVAAYLSEKPLGEAIKKAVKLGLIKSRDELFITLQALN 82 >UniRef50_Q2H1Q3 Cluster: Putative uncharacterized protein; n=1; Chaetomium globosum|Rep: Putative uncharacterized protein - Chaetomium globosum (Soil fungus) Length = 274 Score = 69.7 bits (163), Expect = 9e-11 Identities = 34/88 (38%), Positives = 49/88 (55%), Gaps = 2/88 (2%) Frame = +1 Query: 514 TDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLXHAXVK--PVVNX 687 T + K + D D+VDTW+ M+ L+ ++++GVSNF K LERLL K P VN Sbjct: 93 TPEDLKKHYPDWDFVDTWREMQKLMDTNKIRNLGVSNFGIKNLERLLNDPSCKIVPAVNQ 152 Query: 688 VECHPYLNXKRLKEFCXXRGVXIXXYSP 771 +E HP +L +C +G+ YSP Sbjct: 153 IELHPGNPSPKLIAYCAEKGIHCSGYSP 180 >UniRef50_P47137 Cluster: Probable oxidoreductase YJR096W; n=8; Saccharomycetales|Rep: Probable oxidoreductase YJR096W - Saccharomyces cerevisiae (Baker's yeast) Length = 282 Score = 69.7 bits (163), Expect = 9e-11 Identities = 30/74 (40%), Positives = 49/74 (66%), Gaps = 2/74 (2%) Frame = +1 Query: 556 VDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLXHAXV--KPVVNXVECHPYLNXKRLKE 729 ++TW+AM+ V EGLVKSIGVSN+ K ++ LL + KPVVN +E P++ + L + Sbjct: 125 LETWRAMQEAVDEGLVKSIGVSNYGKKHIDELLNWPELKHKPVVNQIEISPWIMRQELAD 184 Query: 730 FCXXRGVXIXXYSP 771 +C +G+ + ++P Sbjct: 185 YCKSKGLVVEAFAP 198 Score = 67.3 bits (157), Expect = 5e-10 Identities = 32/88 (36%), Positives = 50/88 (56%), Gaps = 2/88 (2%) Frame = +3 Query: 180 PXFGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIKE--GVVTRE 353 P LGT+ + + V + + GYRH D A +YGNEKEVG+ I + E G RE Sbjct: 15 PSIALGTYDIPRSQTAEIVYEGVKCGYRHFDTAVLYGNEKEVGDGIIKWLNEDPGNHKRE 74 Query: 354 DLFITSKLWNTFHRPDLVRGALQETLEQ 437 ++F T+KLWN+ + + A+++ L + Sbjct: 75 EIFYTTKLWNSQNGYKRAKAAIRQCLNE 102 >UniRef50_A7P424 Cluster: Chromosome chr1 scaffold_5, whole genome shotgun sequence; n=1; Vitis vinifera|Rep: Chromosome chr1 scaffold_5, whole genome shotgun sequence - Vitis vinifera (Grape) Length = 247 Score = 69.3 bits (162), Expect = 1e-10 Identities = 36/80 (45%), Positives = 52/80 (65%), Gaps = 2/80 (2%) Frame = +3 Query: 213 PGE-VTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIKEGVV-TREDLFITSKLWNT 386 P E + ++ AI++GYRH DC Y +EK +GEAI +K G++ +R++LFITSKLW + Sbjct: 30 PSETMIDSILTAIELGYRHFDCVAAYLSEKPLGEAIKKAVKLGLIKSRDELFITSKLWCS 89 Query: 387 FHRPDLVRGALQETLEQSEL 446 D V ALQ TL+ S + Sbjct: 90 DAHHDRVLPALQNTLKISSI 109 Score = 62.9 bits (146), Expect = 1e-08 Identities = 46/115 (40%), Positives = 55/115 (47%), Gaps = 2/115 (1%) Frame = +1 Query: 436 NLNFQYLDLYLIHWPQAYKEDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIG 615 NL YLDLYLIHW DG L +D WKAME K L K+IG Sbjct: 115 NLQLDYLDLYLIHW-----SDGHL------------PIDLGSVWKAMEDFQKLSLTKAIG 157 Query: 616 VSNFNSKQLERLLXHAXVKPVVNXV-ECHPYLNXKRLKEFCXXR-GVXIXXYSPP 774 VSNF+ +LE LL A + P VN V E P L + + R V I ++PP Sbjct: 158 VSNFSCNKLEELLQTASILPAVNQVSENEPTLAAEEAQGVIYVRKRVSISRHTPP 212 >UniRef50_Q7M4N1 Cluster: Dihydrodiol dehydrogenase DD2; n=2; Homo sapiens|Rep: Dihydrodiol dehydrogenase DD2 - Homo sapiens (Human) Length = 188 Score = 69.3 bits (162), Expect = 1e-10 Identities = 34/68 (50%), Positives = 46/68 (67%) Frame = +3 Query: 243 AIDIGYRHIDCAYVYGNEKEVGEAITSKIKEGVVTREDLFITSKLWNTFHRPDLVRGALQ 422 AI+ G+ HID A+VY NE++VG I +G V RED+F TSKLW+ HRP+LVR AL+ Sbjct: 2 AIEAGFHHIDSAHVYNNEEQVG------IADGSVKREDIFYTSKLWSNSHRPELVRPALE 55 Query: 423 ETLEQSEL 446 + +L Sbjct: 56 ILFDTVDL 63 Score = 64.9 bits (151), Expect = 3e-09 Identities = 37/82 (45%), Positives = 48/82 (58%), Gaps = 2/82 (2%) Frame = +1 Query: 529 KIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLXHAXVK--PVVNXVECHP 702 +I F VD TW+AME KSIGVSNFN + LE +L +K PV N VECHP Sbjct: 55 EILFDTVDLCATWEAME--------KSIGVSNFNHRLLEMILNKPGLKYKPVCNQVECHP 106 Query: 703 YLNXKRLKEFCXXRGVXIXXYS 768 Y N ++L +FC + + + YS Sbjct: 107 YFNQRKLLDFC--KDIVLVAYS 126 >UniRef50_O14088 Cluster: Xylose and arabinose reductase; n=1; Schizosaccharomyces pombe|Rep: Xylose and arabinose reductase - Schizosaccharomyces pombe (Fission yeast) Length = 275 Score = 69.3 bits (162), Expect = 1e-10 Identities = 27/75 (36%), Positives = 50/75 (66%), Gaps = 1/75 (1%) Frame = +1 Query: 550 DYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLL-XHAXVKPVVNXVECHPYLNXKRLK 726 D +++WKA+E V+EG +++IGVSNF ++ LL H + P VN +E HP+ + +++ Sbjct: 116 DRIESWKALEKGVEEGKLRAIGVSNFGPHHIQELLDSHPKIIPCVNQIELHPFCSQQKVV 175 Query: 727 EFCXXRGVXIXXYSP 771 ++C +G+ + Y+P Sbjct: 176 DYCESKGIQLAAYAP 190 Score = 52.4 bits (120), Expect = 1e-05 Identities = 26/66 (39%), Positives = 37/66 (56%) Frame = +3 Query: 180 PXFGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIKEGVVTREDL 359 P F G++ + +V A+ GYRHID A +Y NE + G AI ++E RED+ Sbjct: 15 PQFAYGSYMVNRTKCFDSVYAALQCGYRHIDSAQMYHNEADCGRAILKFMEETGTKREDI 74 Query: 360 FITSKL 377 + TSKL Sbjct: 75 WFTSKL 80 >UniRef50_Q890A0 Cluster: Oxidoreductase; n=6; Lactobacillales|Rep: Oxidoreductase - Lactobacillus plantarum Length = 282 Score = 68.9 bits (161), Expect = 2e-10 Identities = 37/116 (31%), Positives = 60/116 (51%) Frame = +1 Query: 424 RPWNNLNFQYLDLYLIHWPQAYKEDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLV 603 R NL Y+DLYL+H P +P Q G++ D +D W+AME + + G Sbjct: 95 RSLKNLGLDYVDLYLVHAP---------WPWGQVGRVY--DEANLDVWQAMEAIYQSGRA 143 Query: 604 KSIGVSNFNSKQLERLLXHAXVKPVVNXVECHPYLNXKRLKEFCXXRGVXIXXYSP 771 K+IGVSNF + L+ +L A + P+VN ++ + ++ +F + + YSP Sbjct: 144 KAIGVSNFAVRDLKNILNQATIPPMVNQIQYYLGFTEPKITKFSEEHAMLVEAYSP 199 Score = 60.1 bits (139), Expect = 7e-08 Identities = 31/67 (46%), Positives = 41/67 (61%), Gaps = 1/67 (1%) Frame = +3 Query: 180 PXFGLGTWKSKPGEVT-QAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIKEGVVTRED 356 P GTW+ GE T QAV+ A+ GYRHID A Y NE VG+A I++ + RE Sbjct: 17 PKVAFGTWQIPGGEATYQAVRAALAAGYRHIDTALAYQNEASVGQA----IRDSGIPREQ 72 Query: 357 LFITSKL 377 +F+T+KL Sbjct: 73 IFVTTKL 79 >UniRef50_A3UJS6 Cluster: Oxidoreductase; n=3; Alphaproteobacteria|Rep: Oxidoreductase - Oceanicaulis alexandrii HTCC2633 Length = 275 Score = 68.9 bits (161), Expect = 2e-10 Identities = 32/86 (37%), Positives = 51/86 (59%) Frame = +3 Query: 180 PXFGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIKEGVVTREDL 359 P G GTW+ + + + V A+ GYRHID A +YGNE VG+ K+ V RED Sbjct: 13 PKLGFGTWQLEDEDAARGVATALKTGYRHIDTAQIYGNEAAVGDG----WKQSGVKREDF 68 Query: 360 FITSKLWNTFHRPDLVRGALQETLEQ 437 F+T+K+W R ++ +++E+L++ Sbjct: 69 FLTTKVWRDKFRDGDLQASVKESLDK 94 Score = 56.8 bits (131), Expect = 7e-07 Identities = 36/113 (31%), Positives = 50/113 (44%) Frame = +1 Query: 433 NNLNFQYLDLYLIHWPQAYKEDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSI 612 + L Y+DL L+HWP +V +T KAM + + G V+ I Sbjct: 93 DKLKTDYVDLLLLHWP-------------------VPEVPIAETMKAMNEVKEAGQVRHI 133 Query: 613 GVSNFNSKQLERLLXHAXVKPVVNXVECHPYLNXKRLKEFCXXRGVXIXXYSP 771 GVSNF L+ H+ V N VE HPYL+ + C G+ + YSP Sbjct: 134 GVSNFTVDLLDEARAHSGAPLVANQVEYHPYLDQNAVLTACRAAGMAMTAYSP 186 >UniRef50_Q5B034 Cluster: Putative uncharacterized protein; n=1; Emericella nidulans|Rep: Putative uncharacterized protein - Emericella nidulans (Aspergillus nidulans) Length = 186 Score = 68.9 bits (161), Expect = 2e-10 Identities = 42/87 (48%), Positives = 54/87 (62%) Frame = +3 Query: 174 LFPXFGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIKEGVVTRE 353 L P GLGTWKS+PGEV +A+ A+ GYRHID A +G V RE Sbjct: 14 LIPAVGLGTWKSEPGEVARALAHALKTGYRHIDAA--------LG-----------VPRE 54 Query: 354 DLFITSKLWNTFHRPDLVRGALQETLE 434 ++FITSKLWNT H+P++ G LQ+TL+ Sbjct: 55 EIFITSKLWNT-HQPNIKEG-LQKTLD 79 Score = 41.9 bits (94), Expect = 0.021 Identities = 22/66 (33%), Positives = 32/66 (48%), Gaps = 1/66 (1%) Frame = +1 Query: 487 YKEDGSLFPTDQSG-KIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLXHA 663 Y E L P + G + D +TW+ ME K G K+IGV+N++ LE LL Sbjct: 89 YNETSDLLPVNPDGTRAVDRSWDQSETWRQMEDFYKSGKAKAIGVANWSIPYLEELLADE 148 Query: 664 XVKPVV 681 + +V Sbjct: 149 VTRAIV 154 >UniRef50_A2UAH0 Cluster: Aldo/keto reductase; n=1; Bacillus coagulans 36D1|Rep: Aldo/keto reductase - Bacillus coagulans 36D1 Length = 273 Score = 68.5 bits (160), Expect = 2e-10 Identities = 35/112 (31%), Positives = 58/112 (51%) Frame = +1 Query: 436 NLNFQYLDLYLIHWPQAYKEDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIG 615 N + LDLYLIH P + E G+ + + ++ WKAME + + G ++IG Sbjct: 99 NFGLEQLDLYLIHAPWPWSEKGADYTKEN-----------IEVWKAMEEIYESGRCRAIG 147 Query: 616 VSNFNSKQLERLLXHAXVKPVVNXVECHPYLNXKRLKEFCXXRGVXIXXYSP 771 VSNF+ L+ ++ +A +KP+VN + + + FC G+ + YSP Sbjct: 148 VSNFSVSDLKAVMENAKIKPMVNQIRYFIGHTQEDVTAFCQDNGILVEAYSP 199 Score = 65.7 bits (153), Expect = 1e-09 Identities = 33/67 (49%), Positives = 43/67 (64%), Gaps = 1/67 (1%) Frame = +3 Query: 180 PXFGLGTWKSKPGEVT-QAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIKEGVVTRED 356 P GLGTW+ GE T AV A+ GYRHID AY Y NE+ VG+A +++ + R D Sbjct: 17 PKIGLGTWQVPNGETTYHAVSFALKNGYRHIDTAYAYHNEESVGKA----VRDSGIDRRD 72 Query: 357 LFITSKL 377 +F+TSKL Sbjct: 73 IFVTSKL 79 >UniRef50_Q5XJM7 Cluster: Zgc:101765; n=5; Eumetazoa|Rep: Zgc:101765 - Danio rerio (Zebrafish) (Brachydanio rerio) Length = 288 Score = 68.1 bits (159), Expect = 3e-10 Identities = 38/117 (32%), Positives = 53/117 (45%) Frame = +1 Query: 418 CRRPWNNLNFQYLDLYLIHWPQAYKEDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEG 597 C++ L Y+DLYLIHWP P + + +W+ +E EG Sbjct: 96 CQKSLEQLGLGYIDLYLIHWPGTQG-----LPVGDKRNPE----NRAQSWRVLEEFYSEG 146 Query: 598 LVKSIGVSNFNSKQLERLLXHAXVKPVVNXVECHPYLNXKRLKEFCXXRGVXIXXYS 768 ++IGVSN+ + ++ LL V P V VE HP L L+ C RGV YS Sbjct: 147 KFRAIGVSNYTVEHMQELLKSCKVPPAVLQVEFHPKLLQNDLRGLCKIRGVCFQAYS 203 Score = 57.2 bits (132), Expect = 5e-07 Identities = 36/93 (38%), Positives = 51/93 (54%), Gaps = 1/93 (1%) Frame = +3 Query: 180 PXFGLGTWKSKPGEVT-QAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIKEGVVTRED 356 P GLGT++ + E T AV A+ GYR D A VY NE +G A+ + + ++RED Sbjct: 17 PLLGLGTFRLQGQEDTYSAVDAALKAGYRAFDTAAVYRNEAHLGHALRCLLPKHGLSRED 76 Query: 357 LFITSKLWNTFHRPDLVRGALQETLEQSELSVL 455 +FITSKL + R Q++LEQ L + Sbjct: 77 VFITSKL-GPKDQGSKARNGCQKSLEQLGLGYI 108 >UniRef50_A7ALH6 Cluster: Putative uncharacterized protein; n=1; Parabacteroides merdae ATCC 43184|Rep: Putative uncharacterized protein - Parabacteroides merdae ATCC 43184 Length = 301 Score = 67.7 bits (158), Expect = 4e-10 Identities = 37/112 (33%), Positives = 58/112 (51%) Frame = +1 Query: 436 NLNFQYLDLYLIHWPQAYKEDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIG 615 +L Y+DL LIHWP G I+ +TW+ +E V +G ++SIG Sbjct: 121 DLGTDYIDLVLIHWPV-------------KGHIK-------ETWQILEEYVDKGKIRSIG 160 Query: 616 VSNFNSKQLERLLXHAXVKPVVNXVECHPYLNXKRLKEFCXXRGVXIXXYSP 771 VSNFN L+ LL +A ++PVVN +E PY+ + + +G+ + + P Sbjct: 161 VSNFNPHHLDELLEYARIRPVVNQIEIEPYMTQHDVVGYTFRKGIQVEAWGP 212 Score = 53.6 bits (123), Expect = 6e-06 Identities = 35/84 (41%), Positives = 48/84 (57%) Frame = +3 Query: 180 PXFGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIKEGVVTREDL 359 P G+GT+ K + V AI +G+R ID A YGNEKEVGE I + G + R +L Sbjct: 41 PQLGVGTFLVKDN-AAERVCHAIKVGFRLIDTAQGYGNEKEVGEGI---CRSG-IDRREL 95 Query: 360 FITSKLWNTFHRPDLVRGALQETL 431 FIT+K+ R VR +L ++L Sbjct: 96 FITTKVNTMEMRGGTVRQSLDKSL 119 >UniRef50_A1UEC5 Cluster: 2,5-didehydrogluconate reductase; n=20; Corynebacterineae|Rep: 2,5-didehydrogluconate reductase - Mycobacterium sp. (strain KMS) Length = 283 Score = 67.7 bits (158), Expect = 4e-10 Identities = 37/117 (31%), Positives = 54/117 (46%) Frame = +1 Query: 421 RRPWNNLNFQYLDLYLIHWPQAYKEDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGL 600 R L Y+DLYLIHWP GK Y+D+W + ++G+ Sbjct: 99 RASLERLGLDYVDLYLIHWPAG-----------DHGK-------YIDSWGGLMKAKQDGV 140 Query: 601 VKSIGVSNFNSKQLERLLXHAXVKPVVNXVECHPYLNXKRLKEFCXXRGVXIXXYSP 771 +SIGV NFN++ L ++ + P +N +E HP LN L+E G+ Y P Sbjct: 141 ARSIGVCNFNAEHLSNIIDLSFFTPAINQIELHPLLNQAELREVNAGYGIVTEAYGP 197 Score = 52.0 bits (119), Expect = 2e-05 Identities = 26/66 (39%), Positives = 39/66 (59%) Frame = +3 Query: 180 PXFGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIKEGVVTREDL 359 P GLG + E ++V A++ GYR ID A VYGNE VG A+ + + RE++ Sbjct: 23 PVLGLGVGELSEAEAERSVAAALEAGYRLIDTAAVYGNEAAVGRAVNA----SGIPREEI 78 Query: 360 FITSKL 377 ++T+KL Sbjct: 79 YVTTKL 84 >UniRef50_Q572D2 Cluster: Aldo-keto reductase, putative; n=1; Phytophthora infestans|Rep: Aldo-keto reductase, putative - Phytophthora infestans (Potato late blight fungus) Length = 255 Score = 67.3 bits (157), Expect = 5e-10 Identities = 30/70 (42%), Positives = 49/70 (70%), Gaps = 1/70 (1%) Frame = +3 Query: 180 PXFGLGTWKSKPG-EVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIKEGVVTRED 356 P GLG ++S+PG E A+ ++ +GYRHID A +YGNE++VG A +++ + RE+ Sbjct: 17 PMIGLGVYQSEPGPETYNAILTSLKLGYRHIDTAEIYGNEEDVGRA----VRDSGIPREE 72 Query: 357 LFITSKLWNT 386 +F+T+KL+ T Sbjct: 73 IFVTTKLFTT 82 Score = 55.2 bits (127), Expect = 2e-06 Identities = 25/58 (43%), Positives = 36/58 (62%) Frame = +1 Query: 559 DTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLXHAXVKPVVNXVECHPYLNXKRLKEF 732 DTW+A+E L ++ ++ IGVSNFN L L A +KP VN VE HP++ + L + Sbjct: 121 DTWRAVEDLREQETLRDIGVSNFNETLLATLRKTAHIKPAVNQVELHPWMMRQSLVNY 178 >UniRef50_Q4WUF7 Cluster: Aldo-keto reductase, putative; n=3; Pezizomycotina|Rep: Aldo-keto reductase, putative - Aspergillus fumigatus (Sartorya fumigata) Length = 283 Score = 67.3 bits (157), Expect = 5e-10 Identities = 33/86 (38%), Positives = 52/86 (60%) Frame = +3 Query: 180 PXFGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIKEGVVTREDL 359 P G G ++S G+ Q+ A++ GYRHID A YGNEKEVGEA +++ + R D+ Sbjct: 21 PRLGFGVYRSPTGQCVQSSLRALEAGYRHIDTAQFYGNEKEVGEA----LRKCGIPRSDV 76 Query: 360 FITSKLWNTFHRPDLVRGALQETLEQ 437 F+T+K+ + P+ L E++E+ Sbjct: 77 FVTTKILSPAGSPEATYQKLLESVEK 102 Score = 65.3 bits (152), Expect = 2e-09 Identities = 28/72 (38%), Positives = 45/72 (62%), Gaps = 1/72 (1%) Frame = +1 Query: 559 DTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLXHAXV-KPVVNXVECHPYLNXKRLKEFC 735 + W+A+E L++EG +SIGVSNF K +E + +A V P VN +E HP+ + ++ +C Sbjct: 127 ELWQALERLLEEGKTRSIGVSNFGVKHIEEMKAYAKVWPPHVNQIELHPWCQQRVIEAYC 186 Query: 736 XXRGVXIXXYSP 771 G+ + YSP Sbjct: 187 KRNGIVVEAYSP 198 >UniRef50_Q07551 Cluster: NADPH-dependent alpha-keto amide reductase; n=4; Saccharomycetales|Rep: NADPH-dependent alpha-keto amide reductase - Saccharomyces cerevisiae (Baker's yeast) Length = 312 Score = 67.3 bits (157), Expect = 5e-10 Identities = 41/109 (37%), Positives = 55/109 (50%), Gaps = 2/109 (1%) Frame = +1 Query: 451 YLDLYLIHWPQAYKEDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFN 630 Y+DLYL+H P KE L + WK ME L K G K+IGVSNF Sbjct: 115 YVDLYLLHSPFVSKEVNGL--------------SLEEAWKDMEQLYKSGKAKNIGVSNFA 160 Query: 631 SKQLERLLXHAXVKPVVNXVECHPYLNXKR--LKEFCXXRGVXIXXYSP 771 + L+R+L A VKP VN +E P+L + + +FC + + YSP Sbjct: 161 VEDLQRILKVAEVKPQVNQIEFSPFLQNQTPGIYKFCQEHDILVEAYSP 209 >UniRef50_Q8G7K9 Cluster: Dehydrogenase or reductase protein; n=4; Bifidobacterium|Rep: Dehydrogenase or reductase protein - Bifidobacterium longum Length = 289 Score = 66.9 bits (156), Expect = 6e-10 Identities = 36/111 (32%), Positives = 50/111 (45%) Frame = +1 Query: 439 LNFQYLDLYLIHWPQAYKEDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGV 618 L Y+D+Y+IHWP + D DTWKA L EG+ +++GV Sbjct: 109 LQLDYVDMYMIHWPTPF------------------DWRSTDTWKAFVKLRDEGMARTLGV 150 Query: 619 SNFNSKQLERLLXHAXVKPVVNXVECHPYLNXKRLKEFCXXRGVXIXXYSP 771 NF L+RL P VN +E HP + + FC G+ + YSP Sbjct: 151 CNFMPADLKRLHEETGAWPAVNQIELHPTWQQREVVAFCKEHGIAVEAYSP 201 Score = 50.4 bits (115), Expect = 6e-05 Identities = 30/89 (33%), Positives = 44/89 (49%) Frame = +3 Query: 180 PXFGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIKEGVVTREDL 359 P GLG + V V+ A++ GYRHID A Y NE VG A+ + RE L Sbjct: 23 PQVGLGVLRIDDEGVVPVVESALEAGYRHIDGAAGYNNEAGVGRALAASGYNKGAKRETL 82 Query: 360 FITSKLWNTFHRPDLVRGALQETLEQSEL 446 ++T+KL ++ D A +L+ +L Sbjct: 83 WVTTKLRDSQQGYDSALKAFDNSLKLLQL 111 >UniRef50_A2RMU6 Cluster: Oxidoreductase, aldo/keto reductase family; n=3; Lactococcus lactis|Rep: Oxidoreductase, aldo/keto reductase family - Lactococcus lactis subsp. cremoris (strain MG1363) Length = 281 Score = 66.9 bits (156), Expect = 6e-10 Identities = 35/70 (50%), Positives = 47/70 (67%), Gaps = 1/70 (1%) Frame = +3 Query: 174 LFPXFGLGTWKSKPGEVTQ-AVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIKEGVVTR 350 + P FGLG ++ GE T+ AVK+A+ +GYRHID A+ Y NE+ VG AI S G+ Sbjct: 12 IIPQFGLGVYQIPEGEATENAVKEALRLGYRHIDTAHAYQNERSVGRAIHS---SGIPIS 68 Query: 351 EDLFITSKLW 380 E ++ITSKLW Sbjct: 69 E-IWITSKLW 77 Score = 63.7 bits (148), Expect = 6e-09 Identities = 32/74 (43%), Positives = 41/74 (55%) Frame = +1 Query: 550 DYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLXHAXVKPVVNXVECHPYLNXKRLKE 729 +Y W A+E VK G VKSIG+SNF+ ++L L A +KP VE HPY K L+E Sbjct: 111 NYRKAWIALENAVKSGKVKSIGISNFDGERLVDLFNFADIKPSALQVETHPYHQQKELQE 170 Query: 730 FCXXRGVXIXXYSP 771 F G I + P Sbjct: 171 FLKPYGTKIESWYP 184 >UniRef50_A7D761 Cluster: Aldo/keto reductase; n=2; Halobacteriaceae|Rep: Aldo/keto reductase - Halorubrum lacusprofundi ATCC 49239 Length = 665 Score = 66.9 bits (156), Expect = 6e-10 Identities = 37/133 (27%), Positives = 57/133 (42%), Gaps = 15/133 (11%) Frame = +1 Query: 418 CRRPWNNLNFQYLDLYLIHWPQAYKEDGSL---------------FPTDQSGKIQFSDVD 552 C L D Y +HWP A + G L FP + G+ +DV Sbjct: 456 CAGSREELGIDAFDCYALHWPSALEHRGELNRLAEKPVERQETLTFPEGEDGEPATADVA 515 Query: 553 YVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLXHAXVKPVVNXVECHPYLNXKRLKEF 732 W+ +E + + G +++G+ N + QLE +L + P + VE HPY L E Sbjct: 516 LATAWRNLEAVHERGWARTLGICNVSRAQLETVLETGEIDPALVQVERHPYRPRNGLVEL 575 Query: 733 CXXRGVXIXXYSP 771 C RG+ + +SP Sbjct: 576 CHGRGIRVVAHSP 588 Score = 52.8 bits (121), Expect = 1e-05 Identities = 30/89 (33%), Positives = 44/89 (49%), Gaps = 3/89 (3%) Frame = +3 Query: 180 PXFGLGTWKSKPGEVTQAVKD---AIDIGYRHIDCAYVYGNEKEVGEAITSKIKEGVVTR 350 P G G + + GE V A+D GYR +D A +YGNE +GE + + G R Sbjct: 377 PAVGFGCSRYRDGEYVDRVDSIATALDAGYRLLDSAELYGNEHRIGELLAA---PGAPDR 433 Query: 351 EDLFITSKLWNTFHRPDLVRGALQETLEQ 437 E +F+ K W T HR + + A + E+ Sbjct: 434 ERVFLLGKAWRTNHRREHLLAACAGSREE 462 >UniRef50_Q88TV9 Cluster: Oxidoreductase; n=4; Lactobacillus|Rep: Oxidoreductase - Lactobacillus plantarum Length = 288 Score = 66.5 bits (155), Expect = 9e-10 Identities = 37/93 (39%), Positives = 53/93 (56%), Gaps = 1/93 (1%) Frame = +3 Query: 180 PXFGLGTWK-SKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIKEGVVTRED 356 P G GT++ G QAVK+A+ IGYRHID A Y NE EVG+A IK+ + R+ Sbjct: 16 PAIGFGTFQIPDDGSTYQAVKEALVIGYRHIDTAVAYFNEDEVGQA----IKDSGIPRDQ 71 Query: 357 LFITSKLWNTFHRPDLVRGALQETLEQSELSVL 455 +++TSKLW + D A+ +L + L + Sbjct: 72 IWVTSKLWLQDYGFDAASRAIDRSLTKLRLDYI 104 Score = 50.0 bits (114), Expect = 8e-05 Identities = 35/116 (30%), Positives = 50/116 (43%) Frame = +1 Query: 424 RPWNNLNFQYLDLYLIHWPQAYKEDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLV 603 R L Y+DLYLIH P + DV W+AME K G + Sbjct: 94 RSLTKLRLDYIDLYLIHQP-------------------YGDVP--GAWQAMEAAQKAGKL 132 Query: 604 KSIGVSNFNSKQLERLLXHAXVKPVVNXVECHPYLNXKRLKEFCXXRGVXIXXYSP 771 KSIGVSN ++ + P VN VE +PY + L++ + V + ++P Sbjct: 133 KSIGVSNMTPTLWQKFVPQFETIPAVNQVEFNPYFQQQPLRQLLAAQDVKLEAWAP 188 >UniRef50_Q15NA5 Cluster: Aldo/keto reductase; n=2; Gammaproteobacteria|Rep: Aldo/keto reductase - Pseudoalteromonas atlantica (strain T6c / BAA-1087) Length = 273 Score = 66.5 bits (155), Expect = 9e-10 Identities = 34/86 (39%), Positives = 53/86 (61%) Frame = +3 Query: 180 PXFGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIKEGVVTREDL 359 P G GT++ K + AV++A+D+GYRHID A Y NE EVG+AI++ ++R +L Sbjct: 12 PTPGFGTYRLKGDDAKLAVENALDVGYRHIDTAQAYENEAEVGDAISA----SKISRGEL 67 Query: 360 FITSKLWNTFHRPDLVRGALQETLEQ 437 F+T+K+W D ++Q +L Q Sbjct: 68 FVTTKVWFDNLSADKFITSVQNSLTQ 93 Score = 50.0 bits (114), Expect = 8e-05 Identities = 33/112 (29%), Positives = 49/112 (43%), Gaps = 1/112 (0%) Frame = +1 Query: 439 LNFQYLDLYLIHWPQAYKEDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGV 618 LN Y+DL L+HWP K+ ++ Y+ KA + + GL + IGV Sbjct: 94 LNTDYVDLLLVHWPSP------------DNKVSMAE--YLKELKACK---ERGLTRHIGV 136 Query: 619 SNFNSKQLERLLXHAXVKPVV-NXVECHPYLNXKRLKEFCXXRGVXIXXYSP 771 SNF QL+ L ++ N +E HP K L +C + + Y P Sbjct: 137 SNFTQSQLDEALSILGKDHILTNQIEVHPNFQNKELVAYCQRNNIQVTAYMP 188 >UniRef50_A4YQ04 Cluster: 2,5-diketo-D-gluconate reductase B; n=15; Proteobacteria|Rep: 2,5-diketo-D-gluconate reductase B - Bradyrhizobium sp. (strain ORS278) Length = 273 Score = 66.5 bits (155), Expect = 9e-10 Identities = 33/89 (37%), Positives = 51/89 (57%) Frame = +3 Query: 180 PXFGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIKEGVVTREDL 359 P GLGT++ + AV+ A+ +GYRHID A +Y NE +G A+ + + REDL Sbjct: 12 PKLGLGTFRMQGTVCRDAVESALALGYRHIDTAEMYANEDAIGAALAA----AQIAREDL 67 Query: 360 FITSKLWNTFHRPDLVRGALQETLEQSEL 446 +T+K+W PD +R A +L++ L Sbjct: 68 HVTTKVWPENLAPDAIRRAFDTSLKKLRL 96 Score = 40.3 bits (90), Expect = 0.064 Identities = 30/111 (27%), Positives = 48/111 (43%) Frame = +1 Query: 439 LNFQYLDLYLIHWPQAYKEDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGV 618 L ++DLYLIHWP G P ++T A++ +EG ++IGV Sbjct: 94 LRLDFVDLYLIHWPAT----GMNLPAA------------METLMALK---QEGRTRAIGV 134 Query: 619 SNFNSKQLERLLXHAXVKPVVNXVECHPYLNXKRLKEFCXXRGVXIXXYSP 771 +NF L++ + N VE H L+ +L + R + + Y P Sbjct: 135 ANFTVALLKQAVEDIQAPVACNQVEYHVMLDQSKLMAYMKSRSIPLVAYCP 185 >UniRef50_A3WP89 Cluster: Aldo/keto reductase; n=1; Idiomarina baltica OS145|Rep: Aldo/keto reductase - Idiomarina baltica OS145 Length = 263 Score = 66.5 bits (155), Expect = 9e-10 Identities = 30/69 (43%), Positives = 45/69 (65%) Frame = +3 Query: 174 LFPXFGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIKEGVVTRE 353 + P FG+GT++ + E+T V AID+GY HID A YGNE +VG+A+ T + Sbjct: 1 MIPQFGMGTFRLEGQELTDLVSAAIDMGYEHIDTAQFYGNEADVGKALAQH------TNK 54 Query: 354 DLFITSKLW 380 D+F+T+K+W Sbjct: 55 DVFVTTKVW 63 Score = 50.8 bits (116), Expect = 5e-05 Identities = 32/107 (29%), Positives = 48/107 (44%), Gaps = 1/107 (0%) Frame = +1 Query: 454 LDLYLIHWPQAYKEDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNS 633 +DL LIHWP P D+ V +T A++ ++GL+K +GVSNF Sbjct: 88 IDLALIHWPS---------PNDE--------VPVEETLDALQKAQQDGLIKHLGVSNFTI 130 Query: 634 KQLERLLXHAXVKPVV-NXVECHPYLNXKRLKEFCXXRGVXIXXYSP 771 L R H ++ N +E HP+ + + C GV + Y P Sbjct: 131 DLLNRAAAHVGKDEILTNQIEVHPFFQNHAITDACKQMGVKVTAYLP 177 >UniRef50_Q21274 Cluster: Putative uncharacterized protein; n=1; Caenorhabditis elegans|Rep: Putative uncharacterized protein - Caenorhabditis elegans Length = 301 Score = 66.5 bits (155), Expect = 9e-10 Identities = 38/110 (34%), Positives = 58/110 (52%) Frame = +1 Query: 439 LNFQYLDLYLIHWPQAYKEDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGV 618 L Y+DL LIH+P+ ++ G+ D +I S V W+ +E + G V+SIGV Sbjct: 109 LQTDYVDLLLIHYPRD-RDTGN----DDDYEINKSRRKIV--WQTLEKAKESGRVRSIGV 161 Query: 619 SNFNSKQLERLLXHAXVKPVVNXVECHPYLNXKRLKEFCXXRGVXIXXYS 768 SN+ L + +A ++PV+N E PYL LK+FC + + YS Sbjct: 162 SNYEVYHLVEMFEYAKIRPVLNQYEYQPYLTRPTLKKFCDLNNIVVQSYS 211 Score = 43.6 bits (98), Expect = 0.007 Identities = 22/67 (32%), Positives = 40/67 (59%), Gaps = 1/67 (1%) Frame = +3 Query: 180 PXFGLGTWKSKPGE-VTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIKEGVVTRED 356 P GLG + + + + +++ A+ GYR D A +Y NE +G ++ + + +TRED Sbjct: 21 PKIGLGISRIETQQDLDVSIEAALKSGYRQFDTANLYKNETFLGNSLKKYLPQFGLTRED 80 Query: 357 LFITSKL 377 +FIT+K+ Sbjct: 81 VFITTKV 87 >UniRef50_Q09632 Cluster: Probable oxidoreductase ZK1290.5; n=2; Caenorhabditis|Rep: Probable oxidoreductase ZK1290.5 - Caenorhabditis elegans Length = 321 Score = 66.5 bits (155), Expect = 9e-10 Identities = 39/111 (35%), Positives = 56/111 (50%) Frame = +1 Query: 439 LNFQYLDLYLIHWPQAYKEDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGV 618 L YLD+Y+IH PQ D + + K TW+ ME L ++ V+SIGV Sbjct: 95 LQTDYLDMYMIHMPQL--PDWIVNQKETKEK----------TWRQMELLYEDEHVRSIGV 142 Query: 619 SNFNSKQLERLLXHAXVKPVVNXVECHPYLNXKRLKEFCXXRGVXIXXYSP 771 SN++ + L+ LL A + P N VE HP+ + LK +C G+ Y P Sbjct: 143 SNYSIEDLDELLEFASILPHANQVELHPWFHQADLKNYCDELGILTMGYCP 193 Score = 44.8 bits (101), Expect = 0.003 Identities = 36/93 (38%), Positives = 48/93 (51%), Gaps = 1/93 (1%) Frame = +3 Query: 180 PXFGLGTWKSKPGEVTQAVKDAID-IGYRHIDCAYVYGNEKEVGEAITSKIKEGVVTRED 356 P GLGT S G AV +I GYR ID A YG EK++G A +K V RE+ Sbjct: 14 PLIGLGTTHSG-GYYHDAVLHSIKKCGYRLIDTAKRYGVEKQLGIA----VKNCSVPREE 68 Query: 357 LFITSKLWNTFHRPDLVRGALQETLEQSELSVL 455 +F+++KLW D V A Q + E+ + L Sbjct: 69 MFLSTKLW-PVDCGDEVYNAFQTSCEKLQTDYL 100 >UniRef50_Q0SFM4 Cluster: Probable 2,5-didehydrogluconate reductase; n=1; Rhodococcus sp. RHA1|Rep: Probable 2,5-didehydrogluconate reductase - Rhodococcus sp. (strain RHA1) Length = 265 Score = 66.1 bits (154), Expect = 1e-09 Identities = 38/92 (41%), Positives = 52/92 (56%) Frame = +3 Query: 180 PXFGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIKEGVVTREDL 359 P GLGTW + T+AV I+ GYR ID A +Y NE VG A+ E V RE+L Sbjct: 5 PPLGLGTWPLTGPDATRAVLSGIEAGYRLIDTATIYDNEDAVGVALA----ECGVPREEL 60 Query: 360 FITSKLWNTFHRPDLVRGALQETLEQSELSVL 455 F+T+KL + H +RGA++ +L+ L L Sbjct: 61 FVTTKLRGSDHVSGDIRGAVERSLKNLGLDRL 92 Score = 45.2 bits (102), Expect = 0.002 Identities = 35/116 (30%), Positives = 47/116 (40%) Frame = +1 Query: 424 RPWNNLNFQYLDLYLIHWPQAYKEDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLV 603 R NL LDL+LIHWP P YV ++AM GLV Sbjct: 82 RSLKNLGLDRLDLFLIHWP---------LPRHNR---------YVAAFEAMLACRDAGLV 123 Query: 604 KSIGVSNFNSKQLERLLXHAXVKPVVNXVECHPYLNXKRLKEFCXXRGVXIXXYSP 771 + +GVSNF L R++ P VN ++ P L ++ GV +SP Sbjct: 124 RHVGVSNFLETHLRRVVAETGESPAVNQIQMDPSLARLPVRRADDELGVSTQSWSP 179 >UniRef50_A1CAM7 Cluster: Aldo-keto reductase, putative; n=9; Dikarya|Rep: Aldo-keto reductase, putative - Aspergillus clavatus Length = 283 Score = 66.1 bits (154), Expect = 1e-09 Identities = 29/72 (40%), Positives = 44/72 (61%), Gaps = 1/72 (1%) Frame = +1 Query: 559 DTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLXHAXV-KPVVNXVECHPYLNXKRLKEFC 735 + W+A+E L++EG KSIGVSNF K +E + +A V P VN +E HP+ + + +C Sbjct: 127 ELWQALEKLLEEGKTKSIGVSNFGVKHIEEMKAYAKVWPPHVNQIELHPWCQQRVIDAYC 186 Query: 736 XXRGVXIXXYSP 771 G+ + YSP Sbjct: 187 KRNGIVVEAYSP 198 Score = 57.6 bits (133), Expect = 4e-07 Identities = 29/86 (33%), Positives = 48/86 (55%) Frame = +3 Query: 180 PXFGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIKEGVVTREDL 359 P G G ++S + Q+ A+ GYR+ID A Y NE+EVGEA ++ + R D+ Sbjct: 21 PRLGFGVYRSPTRQCVQSCLTALQAGYRNIDTAQFYANEQEVGEA----LRTSGIPRSDV 76 Query: 360 FITSKLWNTFHRPDLVRGALQETLEQ 437 F+T+K+ + P+ L E++E+ Sbjct: 77 FVTTKILSPAGSPEATYKKLLESVEK 102 >UniRef50_Q8ET73 Cluster: 2,5-diketo-D-gluconate reductase; n=12; Bacteria|Rep: 2,5-diketo-D-gluconate reductase - Oceanobacillus iheyensis Length = 280 Score = 65.7 bits (153), Expect = 1e-09 Identities = 37/89 (41%), Positives = 49/89 (55%) Frame = +3 Query: 180 PXFGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIKEGVVTREDL 359 P G GT++ + QA+ +AID GYR ID AY Y NE VGEA ++ RE L Sbjct: 17 PKVGFGTYRLNGNDGVQAINNAIDHGYRLIDTAYNYENEGTVGEA----VRRSSTPREQL 72 Query: 360 FITSKLWNTFHRPDLVRGALQETLEQSEL 446 ITSKL +H D +QE+L ++ L Sbjct: 73 LITSKLPGRYHHYDKAVTTIQESLYRANL 101 Score = 60.5 bits (140), Expect = 6e-08 Identities = 34/110 (30%), Positives = 52/110 (47%) Frame = +1 Query: 442 NFQYLDLYLIHWPQAYKEDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVS 621 N Y DLYLIHWP + D+ YV+ W+A+ + G ++SIGV Sbjct: 100 NLDYYDLYLIHWPNPIQ-----------------DI-YVEAWQALIEAKRRGYIRSIGVC 141 Query: 622 NFNSKQLERLLXHAXVKPVVNXVECHPYLNXKRLKEFCXXRGVXIXXYSP 771 NF + LERL P +N +E HP+ N + +++ + +SP Sbjct: 142 NFLPEHLERLKQETGELPTINQIELHPFFNQEDQRKWHQEHQIATESWSP 191 >UniRef50_Q9ZUJ6 Cluster: T2K10.1 protein; n=16; core eudicotyledons|Rep: T2K10.1 protein - Arabidopsis thaliana (Mouse-ear cress) Length = 176 Score = 65.7 bits (153), Expect = 1e-09 Identities = 37/90 (41%), Positives = 47/90 (52%), Gaps = 8/90 (8%) Frame = +1 Query: 397 RTWCA-------VPC-RRPWNNLNFQYLDLYLIHWPQAYKEDGSLFPTDQSGKIQFSDVD 552 + WCA VP +R NL YLDLY+IHWP + K FP D+ F +D Sbjct: 90 KLWCADAHGGLVVPAIKRSLKNLKLDYLDLYIIHWPVSSKPGKYKFPIDED---DFMPMD 146 Query: 553 YVDTWKAMEPLVKEGLVKSIGVSNFNSKQL 642 + W ME + GL K IGVSNF+ K+L Sbjct: 147 FEVVWSEMEECQRLGLAKCIGVSNFSCKKL 176 Score = 58.4 bits (135), Expect = 2e-07 Identities = 33/96 (34%), Positives = 53/96 (55%), Gaps = 4/96 (4%) Frame = +3 Query: 180 PXFGLGTWKS---KPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIKEGVV-T 347 P G GT S +P + + V +AI +GYRH D + Y E+ +GEA+ + G+V + Sbjct: 22 PVLGFGTAASPLPEPTMLKETVIEAIKLGYRHFDTSPRYQTEEPIGEALAEAVSLGLVRS 81 Query: 348 REDLFITSKLWNTFHRPDLVRGALQETLEQSELSVL 455 R + F+T+KLW LV A++ +L+ +L L Sbjct: 82 RSEFFVTTKLWCADAHGGLVVPAIKRSLKNLKLDYL 117 >UniRef50_Q00XM4 Cluster: Aldo/keto reductase family proteins; n=2; Ostreococcus|Rep: Aldo/keto reductase family proteins - Ostreococcus tauri Length = 336 Score = 65.7 bits (153), Expect = 1e-09 Identities = 39/105 (37%), Positives = 51/105 (48%) Frame = +1 Query: 457 DLYLIHWPQAYKEDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSK 636 DL L+HWP KE P + + D TW+A+E +K G ++IGVSN+ Sbjct: 152 DLVLVHWPGRDKES----PDSERHR----DARRW-TWRALENALKMGQCRAIGVSNYELS 202 Query: 637 QLERLLXHAXVKPVVNXVECHPYLNXKRLKEFCXXRGVXIXXYSP 771 L LL VKP VN +E H L+ FC GV + YSP Sbjct: 203 HLRELLQFCDVKPAVNQIELHARFPQTELRAFCESVGVHVVGYSP 247 Score = 58.0 bits (134), Expect = 3e-07 Identities = 36/112 (32%), Positives = 57/112 (50%) Frame = +3 Query: 180 PXFGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIKEGVVTREDL 359 P GT++ + AV+DA+ G++H+D A VYGNE++VGEA+ + +E E + Sbjct: 63 PMLAFGTYRLRGETCRDAVRDALRCGFQHVDTASVYGNERDVGEALRACHRE---VSERI 119 Query: 360 FITSKLWNTFHRPDLVRGALQETLEQSELSVLGSVPDTLAPGLQGRRLSLPD 515 F+TSK+ + R + A + + LG PD + GR PD Sbjct: 120 FVTSKIAPSEMRSEEEAAAAIAGVNER----LGRTPDLVLVHWPGRDKESPD 167 >UniRef50_A0JRJ3 Cluster: 2,5-didehydrogluconate reductase; n=3; Actinobacteria (class)|Rep: 2,5-didehydrogluconate reductase - Arthrobacter sp. (strain FB24) Length = 276 Score = 65.3 bits (152), Expect = 2e-09 Identities = 37/86 (43%), Positives = 47/86 (54%) Frame = +3 Query: 180 PXFGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIKEGVVTREDL 359 P GLGTW +V AV +A++ GYRHID A YGNEK VG I S + R +L Sbjct: 16 PQIGLGTWPLDDHQVAAAVVNAVEGGYRHIDTAVKYGNEKGVGNGIRS----SGLDRSEL 71 Query: 360 FITSKLWNTFHRPDLVRGALQETLEQ 437 FIT+KL F D L +L++ Sbjct: 72 FITTKLDGEFQGQDRAVAGLDGSLKR 97 Score = 59.3 bits (137), Expect = 1e-07 Identities = 38/113 (33%), Positives = 53/113 (46%), Gaps = 2/113 (1%) Frame = +1 Query: 439 LNFQYLDLYLIHWPQAYKEDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGV 618 L Y+DL LIHWP +++ ++ TWK E L +G V+SIGV Sbjct: 98 LGLDYVDLLLIHWPLPRRDE------------------FISTWKTFERLQADGKVRSIGV 139 Query: 619 SNFNSKQLERLLXHAXVKPVVNXVECHPYLNXKRLKEFCXXR--GVXIXXYSP 771 SNF LERL+ V P VN ++ P + R+ + R G+ YSP Sbjct: 140 SNFKPAHLERLMAACDVVPAVNQIQVSPAIT--RIVDIAYNRRHGIVTESYSP 190 >UniRef50_Q4WP69 Cluster: Aldehyde reductase, putative; n=1; Aspergillus fumigatus|Rep: Aldehyde reductase, putative - Aspergillus fumigatus (Sartorya fumigata) Length = 350 Score = 65.3 bits (152), Expect = 2e-09 Identities = 39/98 (39%), Positives = 53/98 (54%), Gaps = 7/98 (7%) Frame = +1 Query: 436 NLNFQYLDLYLI----HWPQAYKEDGSLFPTDQSGKIQFS--DVDYVDTWKAMEPLVKEG 597 +L YLDLYL+ H Y+ P + G +F D+ DTW A E LV G Sbjct: 129 DLQTNYLDLYLLYPLGHILHTYQRH---IPASRPGHKRFRLVDIPIGDTWAAREKLVNAG 185 Query: 598 LVKSIGVSN-FNSKQLERLLXHAXVKPVVNXVECHPYL 708 ++S+GVSN F +++E LL A + P VN +E HPYL Sbjct: 186 KIRSLGVSNLFTIEKMEELLNTADIPPAVNQIEAHPYL 223 Score = 58.4 bits (135), Expect = 2e-07 Identities = 32/68 (47%), Positives = 41/68 (60%) Frame = +3 Query: 252 IGYRHIDCAYVYGNEKEVGEAITSKIKEGVVTREDLFITSKLWNTFHRPDLVRGALQETL 431 +GYRHID A V NE EVG K+ V RE +F+TSKLWNT H P V AL +T+ Sbjct: 72 VGYRHIDSAAVGLNEAEVGRGW----KKLGVPREGIFLTSKLWNTHHHPSHVEEALDKTV 127 Query: 432 EQSELSVL 455 + + + L Sbjct: 128 KDLQTNYL 135 >UniRef50_UPI00006CCCD7 Cluster: oxidoreductase, aldo/keto reductase family protein; n=1; Tetrahymena thermophila SB210|Rep: oxidoreductase, aldo/keto reductase family protein - Tetrahymena thermophila SB210 Length = 323 Score = 64.9 bits (151), Expect = 3e-09 Identities = 35/94 (37%), Positives = 53/94 (56%), Gaps = 2/94 (2%) Frame = +1 Query: 433 NNLNFQYLDLYLIHWPQAYKEDGSLFP--TDQSGKIQFSDVDYVDTWKAMEPLVKEGLVK 606 + L Y+DLYLI W S P T+ G + + + W+ +E V+ G+++ Sbjct: 113 DQLQTSYIDLYLIQW--------SFTPVLTNFDGSVAVNHRPIHEVWRELEECVELGMIR 164 Query: 607 SIGVSNFNSKQLERLLXHAXVKPVVNXVECHPYL 708 SIGV+NFN + + LL +A +KPVVN +E PYL Sbjct: 165 SIGVANFNCQMVLDLLSYAKIKPVVNQIEVTPYL 198 Score = 59.3 bits (137), Expect = 1e-07 Identities = 29/79 (36%), Positives = 49/79 (62%) Frame = +3 Query: 219 EVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIKEGVVTREDLFITSKLWNTFHRP 398 E+T + +A+D GYR+ D A Y NE E+G+A + ++G RED+FIT+KL+ F Sbjct: 43 EMTTLLSNALDFGYRNFDTAKQYRNEVEIGQAFQNIFQQGKYKREDVFITTKLF-PFKIE 101 Query: 399 DLVRGALQETLEQSELSVL 455 ++ +Q +L+Q + S + Sbjct: 102 KKIKEVVQNSLDQLQTSYI 120 >UniRef50_Q927E1 Cluster: Lin2848 protein; n=13; Listeria|Rep: Lin2848 protein - Listeria innocua Length = 280 Score = 64.9 bits (151), Expect = 3e-09 Identities = 39/111 (35%), Positives = 57/111 (51%) Frame = +1 Query: 439 LNFQYLDLYLIHWPQAYKEDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGV 618 L +DLYL+HWP K+D + +TW+A+E L EGLV++IGV Sbjct: 101 LQLDQVDLYLVHWP---KQD-----------------TFFETWRAVEKLYDEGLVRAIGV 140 Query: 619 SNFNSKQLERLLXHAXVKPVVNXVECHPYLNXKRLKEFCXXRGVXIXXYSP 771 SNF + L+RL A V PVV+ +E HP+ + L + + +SP Sbjct: 141 SNFEAHHLDRLRTSANVLPVVDQLETHPHFPNQLLHRYLEELHIVHQAWSP 191 Score = 54.0 bits (124), Expect = 5e-06 Identities = 29/90 (32%), Positives = 50/90 (55%), Gaps = 1/90 (1%) Frame = +3 Query: 180 PXFGLGTWK-SKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIKEGVVTRED 356 P G G +K + + A++ A+D+GYR D A Y NEKE+G+ S + R++ Sbjct: 18 PRHGFGVYKLTDEQRMRTALETAVDVGYRLFDTASFYHNEKELGDFFAS----SGLKRDE 73 Query: 357 LFITSKLWNTFHRPDLVRGALQETLEQSEL 446 F+T+K+WNT D A +++ ++ +L Sbjct: 74 FFVTTKMWNTEQGYDETLRAFEKSQKKLQL 103 >UniRef50_Q5NLW3 Cluster: Putative oxidoreductase; n=1; Zymomonas mobilis|Rep: Putative oxidoreductase - Zymomonas mobilis Length = 273 Score = 64.9 bits (151), Expect = 3e-09 Identities = 41/127 (32%), Positives = 57/127 (44%) Frame = +1 Query: 391 IARTWCAVPCRRPWNNLNFQYLDLYLIHWPQAYKEDGSLFPTDQSGKIQFSDVDYVDTWK 570 + R C V + NL L+LYLIHWP Q K Y +TW+ Sbjct: 79 MGRVNCFVALDKSIRNLGVTSLNLYLIHWP------------GQDRK------RYEETWQ 120 Query: 571 AMEPLVKEGLVKSIGVSNFNSKQLERLLXHAXVKPVVNXVECHPYLNXKRLKEFCXXRGV 750 + + G SIGVSNF L+ ++ + V P VN +E HPY K L+ + RG+ Sbjct: 121 TLIQIRAIGKASSIGVSNFTIDHLDHIIADSGVVPAVNQIELHPYFQQKELRAYHAERGI 180 Query: 751 XIXXYSP 771 +SP Sbjct: 181 VTTSWSP 187 Score = 41.5 bits (93), Expect = 0.028 Identities = 19/56 (33%), Positives = 28/56 (50%) Frame = +3 Query: 180 PXFGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIKEGVVT 347 P G G ++ P + V D+GYR +D A Y NE+ VGE + S+ +T Sbjct: 16 PAIGQGVYQLNPAQAESMVALGYDLGYRAVDTAAWYENEEGVGEGLRSRHARSFIT 71 >UniRef50_Q5FLI5 Cluster: Aldehyde reductase; n=2; Bacteria|Rep: Aldehyde reductase - Lactobacillus acidophilus Length = 278 Score = 64.9 bits (151), Expect = 3e-09 Identities = 33/93 (35%), Positives = 54/93 (58%), Gaps = 1/93 (1%) Frame = +3 Query: 180 PXFGLGTWKSKP-GEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIKEGVVTRED 356 P G G ++ + Q V+D +++GYR +D A +YGNE+ VG+A IK V RED Sbjct: 14 PRLGFGVYQIDDLAQAQQVVEDGLEVGYRLVDTAQIYGNEQAVGDA----IKHSNVPRED 69 Query: 357 LFITSKLWNTFHRPDLVRGALQETLEQSELSVL 455 +FITSK+W + D A +++++ +L + Sbjct: 70 IFITSKIWVDDYGYDNTLKAFDDSMKKLQLDYI 102 Score = 54.8 bits (126), Expect = 3e-06 Identities = 25/74 (33%), Positives = 45/74 (60%) Frame = +1 Query: 550 DYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLXHAXVKPVVNXVECHPYLNXKRLKE 729 DY TW+A+E L +EG +++IGVS+F +++L L+ VKP VN +E + + + ++ Sbjct: 113 DYYGTWRALERLYQEGRIRAIGVSSFWNERLADLITFNDVKPAVNQIETNVWNQEWKSQQ 172 Query: 730 FCXXRGVXIXXYSP 771 + GV ++P Sbjct: 173 YMEKEGVQPEAWAP 186 >UniRef50_Q28P63 Cluster: Aldo/keto reductase; n=4; Rhodobacteraceae|Rep: Aldo/keto reductase - Jannaschia sp. (strain CCS1) Length = 276 Score = 64.9 bits (151), Expect = 3e-09 Identities = 37/116 (31%), Positives = 57/116 (49%) Frame = +1 Query: 424 RPWNNLNFQYLDLYLIHWPQAYKEDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLV 603 R + + LDL LIHWP + D+ Y++TWKA + + EGL+ Sbjct: 93 RSLKTIGVEQLDLVLIHWP-----------------VPSQDL-YLETWKAFQDMRDEGLM 134 Query: 604 KSIGVSNFNSKQLERLLXHAXVKPVVNXVECHPYLNXKRLKEFCXXRGVXIXXYSP 771 +SIG SNFN+ LER++ PV+N +E +P L ++ GV ++P Sbjct: 135 RSIGTSNFNADHLERIIAETGEAPVLNQIELNPMLQQPEMRAVHKAHGVVTQAWTP 190 Score = 58.4 bits (135), Expect = 2e-07 Identities = 28/85 (32%), Positives = 48/85 (56%) Frame = +3 Query: 180 PXFGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIKEGVVTREDL 359 P G G W+ + V+ AI+IGYR ID AY+Y NE +GE ++ + R+++ Sbjct: 16 PQVGFGIWQVPQDIAGETVRSAIEIGYRMIDGAYLYMNEAGLGEG----LRASGLPRDEV 71 Query: 360 FITSKLWNTFHRPDLVRGALQETLE 434 F+T+K+WN R +++ +L+ Sbjct: 72 FVTTKVWNNEQGAAKARASVERSLK 96 >UniRef50_A5DRJ6 Cluster: Putative uncharacterized protein; n=4; Pichia guilliermondii|Rep: Putative uncharacterized protein - Pichia guilliermondii (Yeast) (Candida guilliermondii) Length = 287 Score = 64.9 bits (151), Expect = 3e-09 Identities = 29/74 (39%), Positives = 44/74 (59%), Gaps = 2/74 (2%) Frame = +1 Query: 556 VDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLXHAXV--KPVVNXVECHPYLNXKRLKE 729 ++TWKA++ V G+VKSIGVSNF ++ L + KP+VN +E P+L K L + Sbjct: 128 IETWKALQEAVDSGMVKSIGVSNFGKHHIQELYDWEGLKYKPIVNQIELSPWLMRKDLVD 187 Query: 730 FCXXRGVXIXXYSP 771 +C G+ + Y P Sbjct: 188 YCQNLGIVLEAYCP 201 Score = 52.4 bits (120), Expect = 1e-05 Identities = 30/87 (34%), Positives = 47/87 (54%), Gaps = 1/87 (1%) Frame = +3 Query: 180 PXFGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKI-KEGVVTRED 356 P G+G + + V+ A+D+GYR ID A Y NE+E GE I + + K+ RED Sbjct: 19 PACGVGVYLLPASQTAGIVEKALDVGYRLIDTAQEYENERETGEGIKAWLGKDKNNKRED 78 Query: 357 LFITSKLWNTFHRPDLVRGALQETLEQ 437 + T+K+ N D +L+E+L + Sbjct: 79 VLYTTKITNLNQGYDRTWRSLKESLNK 105 >UniRef50_A4R217 Cluster: Putative uncharacterized protein; n=1; Magnaporthe grisea|Rep: Putative uncharacterized protein - Magnaporthe grisea (Rice blast fungus) (Pyricularia grisea) Length = 208 Score = 64.9 bits (151), Expect = 3e-09 Identities = 32/65 (49%), Positives = 43/65 (66%) Frame = +3 Query: 252 IGYRHIDCAYVYGNEKEVGEAITSKIKEGVVTREDLFITSKLWNTFHRPDLVRGALQETL 431 +GYRHID A+ YGNEK++GEA IKE + RE++F+TSKL T+H P V L +L Sbjct: 1 MGYRHIDGAHAYGNEKQIGEA----IKESGIPREEIFVTSKLAQTWHEPGDVERGLDLSL 56 Query: 432 EQSEL 446 +L Sbjct: 57 RNLQL 61 >UniRef50_Q8ZH36 Cluster: 2,5-diketo-D-gluconic acid reductase B; n=91; Proteobacteria|Rep: 2,5-diketo-D-gluconic acid reductase B - Yersinia pestis Length = 267 Score = 64.9 bits (151), Expect = 3e-09 Identities = 33/86 (38%), Positives = 54/86 (62%) Frame = +3 Query: 180 PXFGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIKEGVVTREDL 359 P FGLGT++ + V +V A+ +GYR ID A +Y NE VG+A I+E + R++L Sbjct: 4 PVFGLGTFRLQDQIVIDSVSQALTLGYRAIDTAQIYENEAPVGQA----IQESGINRDEL 59 Query: 360 FITSKLWNTFHRPDLVRGALQETLEQ 437 FIT+K+W D + +L+E++++ Sbjct: 60 FITTKIWIANLSKDKLIPSLRESIQK 85 Score = 37.5 bits (83), Expect = 0.45 Identities = 29/116 (25%), Positives = 47/116 (40%), Gaps = 1/116 (0%) Frame = +1 Query: 421 RRPWNNLNFQYLDLYLIHWPQAYKEDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGL 600 R L Y+DL LIHWP P D+ +F + KA GL Sbjct: 80 RESIQKLKTDYVDLTLIHWPS---------PNDEVSVAEFMS----ELLKAKGL----GL 122 Query: 601 VKSIGVSNFNSKQLERLLXHAXVKPV-VNXVECHPYLNXKRLKEFCXXRGVXIXXY 765 + IG+SNF +++ + + + N +E P L + + +F G+ + Y Sbjct: 123 TRQIGISNFTIDLMKQAIAAVGAEEIATNQIELSPLLQNRNVVDFAKQNGIAVTSY 178 >UniRef50_Q8EUH6 Cluster: Oxidoreductase; n=1; Mycoplasma penetrans|Rep: Oxidoreductase - Mycoplasma penetrans Length = 285 Score = 64.5 bits (150), Expect = 3e-09 Identities = 27/51 (52%), Positives = 35/51 (68%) Frame = +1 Query: 550 DYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLXHAXVKPVVNXVECHP 702 DY WKA+E L K+G+VK+IGVSNF + +L H VKPV+N +E HP Sbjct: 112 DYYSAWKALEVLYKKGIVKAIGVSNFEADRLVDFCLHVDVKPVINQIELHP 162 Score = 55.6 bits (128), Expect = 2e-06 Identities = 31/68 (45%), Positives = 41/68 (60%), Gaps = 1/68 (1%) Frame = +3 Query: 180 PXFGLGTWKSKPGEVTQAVKDAID-IGYRHIDCAYVYGNEKEVGEAITSKIKEGVVTRED 356 P GLG +K++ + AID GYR ID A VY NE+ VG A IK+ + RED Sbjct: 13 PIIGLGVYKAEGENCENTIIKAIDDYGYRMIDTAQVYFNEEFVGNA----IKQTKIKRED 68 Query: 357 LFITSKLW 380 +FIT+K+W Sbjct: 69 IFITTKVW 76 >UniRef50_A3JU52 Cluster: 2,5-diketo-D-gluconic acid reductase A; n=1; Rhodobacterales bacterium HTCC2150|Rep: 2,5-diketo-D-gluconic acid reductase A - Rhodobacterales bacterium HTCC2150 Length = 334 Score = 64.5 bits (150), Expect = 3e-09 Identities = 29/67 (43%), Positives = 39/67 (58%) Frame = +3 Query: 180 PXFGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIKEGVVTREDL 359 P G GT+ + + AI GYRHID A Y NEK VG I + ++ +TR+DL Sbjct: 49 PAVGFGTYLISNDDAKSTISAAIQAGYRHIDTASGYQNEKTVGAGIKAGLQSAGITRKDL 108 Query: 360 FITSKLW 380 F+T+KLW Sbjct: 109 FVTAKLW 115 Score = 44.0 bits (99), Expect = 0.005 Identities = 34/117 (29%), Positives = 44/117 (37%) Frame = +1 Query: 418 CRRPWNNLNFQYLDLYLIHWPQAYKEDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEG 597 C L Y+DLYLIH P Y D L + W+A+ L G Sbjct: 135 CDASLARLGLDYVDLYLIHAP--YGGDMRL-----------------EQWRALLELQANG 175 Query: 598 LVKSIGVSNFNSKQLERLLXHAXVKPVVNXVECHPYLNXKRLKEFCXXRGVXIXXYS 768 +SIGVSNFN L + P N +E HP+ L + + YS Sbjct: 176 KARSIGVSNFNESHLNEIKAAGLPMPDANQIELHPWSQKPDLLAYMDQHAIAPIAYS 232 >UniRef50_Q7WSY4 Cluster: Putative aldo-keto reductase; n=1; Propionibacterium freudenreichii subsp. shermanii|Rep: Putative aldo-keto reductase - Propionibacterium freudenreichii subsp. shermanii Length = 280 Score = 64.1 bits (149), Expect = 5e-09 Identities = 34/86 (39%), Positives = 49/86 (56%) Frame = +3 Query: 180 PXFGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIKEGVVTREDL 359 P G+GTW K E AV AI+ GYR +D A YGNE+ VG+A ++E R ++ Sbjct: 20 PMLGMGTWPLKGEECRAAVASAIEQGYRLVDTAEAYGNEEAVGKA----VREAGPDRAEI 75 Query: 360 FITSKLWNTFHRPDLVRGALQETLEQ 437 F+T+K +H V AL+ +LE+ Sbjct: 76 FVTTKFSKQWHSRKGVHEALEHSLER 101 Score = 50.0 bits (114), Expect = 8e-05 Identities = 33/111 (29%), Positives = 52/111 (46%) Frame = +1 Query: 439 LNFQYLDLYLIHWPQAYKEDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGV 618 L Y+DL+L+HWP +GS YVD ++ M L ++GL K+IGV Sbjct: 102 LGLDYVDLFLMHWPMP--GEGS----------------YVDAYRGMVELKEQGLAKAIGV 143 Query: 619 SNFNSKQLERLLXHAXVKPVVNXVECHPYLNXKRLKEFCXXRGVXIXXYSP 771 SNF L+ L+ + P VN ++ P +++F + +SP Sbjct: 144 SNFKVHHLDDLITEG-MTPEVNQIQLDPSRPRLEVRDFLDNHDIVTEAWSP 193 >UniRef50_Q043M4 Cluster: Aldo/keto reductase of diketogulonate reductase family; n=2; Lactobacillus|Rep: Aldo/keto reductase of diketogulonate reductase family - Lactobacillus gasseri (strain ATCC 33323 / DSM 20243) Length = 273 Score = 64.1 bits (149), Expect = 5e-09 Identities = 35/111 (31%), Positives = 53/111 (47%) Frame = +1 Query: 439 LNFQYLDLYLIHWPQAYKEDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGV 618 + Y DL LIHWP + +DTW A+E K G ++IG+ Sbjct: 93 IGLDYFDLVLIHWPMGHD---------------------IDTWHALEAAYKAGKTRAIGI 131 Query: 619 SNFNSKQLERLLXHAXVKPVVNXVECHPYLNXKRLKEFCXXRGVXIXXYSP 771 SNFNS+Q L+ + V+P+V+ +E H +L ++ EF + YSP Sbjct: 132 SNFNSRQTLDLIHQSSVRPMVDQIETHLFLQQWKMHEFLEKENIVHESYSP 182 Score = 58.0 bits (134), Expect = 3e-07 Identities = 29/65 (44%), Positives = 41/65 (63%) Frame = +3 Query: 180 PXFGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIKEGVVTREDL 359 P FG GT++ P + QAV A + GYR ID A Y NE++VGEA +K + R+++ Sbjct: 13 PIFGFGTYEISPDQTKQAVLSAFEEGYRLIDTAQYYQNEQQVGEA----VKASGLNRDEV 68 Query: 360 FITSK 374 FIT+K Sbjct: 69 FITTK 73 >UniRef50_P15339 Cluster: 2,5-diketo-D-gluconic acid reductase B; n=6; Actinomycetales|Rep: 2,5-diketo-D-gluconic acid reductase B - Corynebacterium sp. (strain SHS752001) Length = 277 Score = 64.1 bits (149), Expect = 5e-09 Identities = 39/113 (34%), Positives = 52/113 (46%) Frame = +1 Query: 433 NNLNFQYLDLYLIHWPQAYKEDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSI 612 + L +DL LIHW P G+ ++DTW+ M + GLV+SI Sbjct: 96 DRLGLDVIDLQLIHW-----------PNPSVGR-------WLDTWRGMIDAREAGLVRSI 137 Query: 613 GVSNFNSKQLERLLXHAXVKPVVNXVECHPYLNXKRLKEFCXXRGVXIXXYSP 771 GVSNF L+ L+ V P VN VE HPY L+ F G+ +SP Sbjct: 138 GVSNFTEPMLKTLIDETGVTPAVNQVELHPYFPQAALRAFHDEHGIRTESWSP 190 Score = 48.0 bits (109), Expect = 3e-04 Identities = 31/81 (38%), Positives = 43/81 (53%), Gaps = 4/81 (4%) Frame = +3 Query: 189 GLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIKEGVVTREDLFIT 368 GLGT+ + E A+ AID GYR +D A Y NE EVG A ++ V R++L + Sbjct: 19 GLGTYNLRGDEGVAAMVAAIDSGYRLLDTAVNYENESEVGRA----VRASSVDRDELIVA 74 Query: 369 SKLWNTFH----RPDLVRGAL 419 SK+ H D +RG+L Sbjct: 75 SKIPGRQHGRAEAVDSIRGSL 95 >UniRef50_Q5UX52 Cluster: Oxidoreductase aldo/keto reductase family; n=1; Haloarcula marismortui|Rep: Oxidoreductase aldo/keto reductase family - Haloarcula marismortui (Halobacterium marismortui) Length = 274 Score = 63.7 bits (148), Expect = 6e-09 Identities = 33/86 (38%), Positives = 50/86 (58%) Frame = +3 Query: 180 PXFGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIKEGVVTREDL 359 P GLGTW+ + V+ A+ +GYRHID A YGNE++VG + + V RED+ Sbjct: 12 PALGLGTWQLTGQSCRETVETALGMGYRHIDTAQAYGNERQVGLGMDA----AAVDREDV 67 Query: 360 FITSKLWNTFHRPDLVRGALQETLEQ 437 F+T+KL + VR + +E+L + Sbjct: 68 FLTTKLDGSNRDERSVRRSTRESLNK 93 Score = 60.9 bits (141), Expect = 4e-08 Identities = 39/117 (33%), Positives = 55/117 (47%) Frame = +1 Query: 421 RRPWNNLNFQYLDLYLIHWPQAYKEDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGL 600 R N L YLDL LIHWP T + +T AM +V+EGL Sbjct: 88 RESLNKLGTDYLDLLLIHWPN----------TPWMASLS-------ETLGAMNDVVEEGL 130 Query: 601 VKSIGVSNFNSKQLERLLXHAXVKPVVNXVECHPYLNXKRLKEFCXXRGVXIXXYSP 771 V+ IGVSNF+ L+R + + V+ HPY + ++L ++C V + YSP Sbjct: 131 VRHIGVSNFSPSLLDRARDISSAPIFTDQVQYHPYWDQRKLLDYCRIHDVLLTAYSP 187 >UniRef50_A3VHZ9 Cluster: Oxidoreductase; n=1; Rhodobacterales bacterium HTCC2654|Rep: Oxidoreductase - Rhodobacterales bacterium HTCC2654 Length = 278 Score = 63.3 bits (147), Expect = 8e-09 Identities = 35/92 (38%), Positives = 51/92 (55%) Frame = +3 Query: 180 PXFGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIKEGVVTREDL 359 P GLGTW E +AV AI+ GYR ID A Y NE VG+ I++ V R+++ Sbjct: 19 PQLGLGTWPMTDDEAAKAVATAIETGYRLIDTAENYKNETGVGQG----IRDAGVARDEV 74 Query: 360 FITSKLWNTFHRPDLVRGALQETLEQSELSVL 455 F+T+K+ +H D R A + +LE+ L + Sbjct: 75 FLTTKMNKQWHSVDGARRACEASLERLGLDYI 106 Score = 46.8 bits (106), Expect = 7e-04 Identities = 36/126 (28%), Positives = 51/126 (40%) Frame = +1 Query: 418 CRRPWNNLNFQYLDLYLIHWPQAYKEDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEG 597 C L Y+DL+LIHWP DQ YV+ ++ + L+ G Sbjct: 94 CEASLERLGLDYIDLFLIHWPNP----------DQG--------TYVEAFEGLTRLLDAG 135 Query: 598 LVKSIGVSNFNSKQLERLLXHAXVKPVVNXVECHPYLNXKRLKEFCXXRGVXIXXYSPPR 777 LV++IG SNF L L V P VN ++ PY + +G+ +SP Sbjct: 136 LVRAIGTSNFLPHHLNDLFAAGFV-PHVNQIQLDPYHLRPDITAIHAAKGIVTESWSPIG 194 Query: 778 XXGXXL 795 G L Sbjct: 195 RAGEML 200 >UniRef50_Q5V663 Cluster: Aldehyde reductase; n=6; Halobacteriaceae|Rep: Aldehyde reductase - Haloarcula marismortui (Halobacterium marismortui) Length = 279 Score = 63.3 bits (147), Expect = 8e-09 Identities = 32/87 (36%), Positives = 52/87 (59%), Gaps = 1/87 (1%) Frame = +3 Query: 180 PXFGLGTWKSKPGE-VTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIKEGVVTRED 356 P GLGTW+++ E ++V+ A++ GYRHID A Y NE VG+ I + V R+D Sbjct: 18 PMLGLGTWQNEDAEQCAESVRTALEAGYRHIDTAQAYDNESAVGDGIAA----ADVDRDD 73 Query: 357 LFITSKLWNTFHRPDLVRGALQETLEQ 437 +F+ +K+W + D V +E+L++ Sbjct: 74 IFLATKVWISNLSHDDVIETTEESLDK 100 Score = 48.4 bits (110), Expect = 2e-04 Identities = 23/71 (32%), Positives = 34/71 (47%) Frame = +1 Query: 559 DTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLXHAXVKPVVNXVECHPYLNXKRLKEFCX 738 +T A + LV GL+ ++GVSNF +E + N VE HP+L L+E Sbjct: 122 ETLPAFDELVDRGLIDNVGVSNFEPHHVETAMDVLDAPVFANQVETHPFLQQSELREHAA 181 Query: 739 XRGVXIXXYSP 771 + + YSP Sbjct: 182 EQDYELVAYSP 192 >UniRef50_UPI00006CA3CB Cluster: oxidoreductase, aldo/keto reductase family protein; n=3; Tetrahymena thermophila SB210|Rep: oxidoreductase, aldo/keto reductase family protein - Tetrahymena thermophila SB210 Length = 299 Score = 62.9 bits (146), Expect = 1e-08 Identities = 29/66 (43%), Positives = 44/66 (66%), Gaps = 1/66 (1%) Frame = +3 Query: 180 PXFGLGTWKSKP-GEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIKEGVVTRED 356 P FGLG+ + + EVT ++ A+D+GYRHID A +Y NE+ +G A+ + EG RED Sbjct: 19 PAFGLGSSRVQSVEEVTNLIRKALDVGYRHIDTAQMYENEQFIGAALKTIFGEGKYKRED 78 Query: 357 LFITSK 374 +F+ +K Sbjct: 79 IFLVTK 84 Score = 60.1 bits (139), Expect = 7e-08 Identities = 38/122 (31%), Positives = 54/122 (44%) Frame = +1 Query: 406 CAVPCRRPWNNLNFQYLDLYLIHWPQAYKEDGSLFPTDQSGKIQFSDVDYVDTWKAMEPL 585 C + L Y+DL LIH P A P+D + V + W E + Sbjct: 93 CLEIMKEQLQKLQVDYVDLLLIHVPLAA-------PSDDYQQWNHKPVHQI--WAEFEEI 143 Query: 586 VKEGLVKSIGVSNFNSKQLERLLXHAXVKPVVNXVECHPYLNXKRLKEFCXXRGVXIXXY 765 GL K +GVSNFN + + LL + +KP+VN +E H + K L EF + + Sbjct: 144 HSLGLAKGLGVSNFNCQMIIDLLAYCKIKPLVNQIELHVFNQQKNLVEFLKKVNIYPVAF 203 Query: 766 SP 771 SP Sbjct: 204 SP 205 >UniRef50_A5PDA8 Cluster: Putative oxidoreductase protein; n=1; Erythrobacter sp. SD-21|Rep: Putative oxidoreductase protein - Erythrobacter sp. SD-21 Length = 272 Score = 62.9 bits (146), Expect = 1e-08 Identities = 34/86 (39%), Positives = 47/86 (54%) Frame = +3 Query: 180 PXFGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIKEGVVTREDL 359 P G GTW+ + + QAV AID+GY ID A +YGNEK VG +GV D+ Sbjct: 16 PQLGFGTWQMEEEDAPQAVSTAIDVGYWLIDTAAIYGNEKGVG--------KGVGEWSDI 67 Query: 360 FITSKLWNTFHRPDLVRGALQETLEQ 437 F+ +K+WN D A ++ LE+ Sbjct: 68 FLQTKIWNDSQGYDRTLRAAEKCLER 93 Score = 62.1 bits (144), Expect = 2e-08 Identities = 35/111 (31%), Positives = 54/111 (48%) Frame = +1 Query: 439 LNFQYLDLYLIHWPQAYKEDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGV 618 L +++D+ LIHWP K+ +VDTWKA+ L G KSIGV Sbjct: 94 LGREHVDMLLIHWPCPEKDQ------------------FVDTWKALIELRDAGKAKSIGV 135 Query: 619 SNFNSKQLERLLXHAXVKPVVNXVECHPYLNXKRLKEFCXXRGVXIXXYSP 771 SNF + L+R++ V P +N +E HP + +++ G+ +SP Sbjct: 136 SNFREEDLKRIIDETGVTPALNQIELHPSFQQRDMRKVHEDLGIVTQSWSP 186 >UniRef50_Q9C1X5 Cluster: Xylose and arabinose reductase; n=1; Schizosaccharomyces pombe|Rep: Xylose and arabinose reductase - Schizosaccharomyces pombe (Fission yeast) Length = 283 Score = 62.5 bits (145), Expect = 1e-08 Identities = 32/70 (45%), Positives = 40/70 (57%) Frame = +3 Query: 174 LFPXFGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIKEGVVTRE 353 + P G G + K E V A+D GYRHID A VYGNE G+AI ++ V R Sbjct: 18 VIPRIGFGAFMLKYNECYGLVTQALDSGYRHIDTAAVYGNEDICGKAIVDWCEKNNVKRT 77 Query: 354 DLFITSKLWN 383 D+F+TSKL N Sbjct: 78 DIFLTSKLAN 87 Score = 60.5 bits (140), Expect = 6e-08 Identities = 27/73 (36%), Positives = 42/73 (57%), Gaps = 1/73 (1%) Frame = +1 Query: 556 VDTWKAMEPLVKEGLVKSIGVSNFNSKQLERL-LXHAXVKPVVNXVECHPYLNXKRLKEF 732 + +WKAME V G ++S+GVSN+ K L+ L + P VN +E HP+L+ + ++ Sbjct: 125 IASWKAMEEFVDSGDIRSVGVSNYGVKHLQELYASNPKFYPCVNQIELHPFLSQDDIVKY 184 Query: 733 CXXRGVXIXXYSP 771 C + I YSP Sbjct: 185 CQSHDIAIEAYSP 197 >UniRef50_Q75E75 Cluster: ABL209Cp; n=1; Eremothecium gossypii|Rep: ABL209Cp - Ashbya gossypii (Yeast) (Eremothecium gossypii) Length = 310 Score = 62.5 bits (145), Expect = 1e-08 Identities = 30/72 (41%), Positives = 44/72 (61%), Gaps = 2/72 (2%) Frame = +1 Query: 562 TWKAMEPLVKEGLVKSIGVSNFNSKQLERLLXHAXVK--PVVNXVECHPYLNXKRLKEFC 735 TW+A+E V EG V+SIGVSN+ + L LL +K PVVN VE +P+L + L ++C Sbjct: 133 TWQALEEAVVEGQVRSIGVSNYGQQHLSELLGWEGLKIRPVVNQVEINPWLCRQELVQYC 192 Query: 736 XXRGVXIXXYSP 771 + + +SP Sbjct: 193 RENNIAVQAFSP 204 Score = 48.0 bits (109), Expect = 3e-04 Identities = 26/85 (30%), Positives = 44/85 (51%), Gaps = 1/85 (1%) Frame = +3 Query: 180 PXFGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIKEGV-VTRED 356 P GLG ++ V V +A+++GYR D A Y NE V I + +K RED Sbjct: 22 PSVGLGVYQVSEQTVQDLVYEALEVGYRLFDSAQAYHNEDGVARGIAAWLKHAPGRRRED 81 Query: 357 LFITSKLWNTFHRPDLVRGALQETL 431 ++ T+K+ H + + +L+++L Sbjct: 82 VYFTTKINTQNHGYEATKKSLEKSL 106 >UniRef50_Q5K8C5 Cluster: Aldo-keto reductase, putative; n=1; Filobasidiella neoformans|Rep: Aldo-keto reductase, putative - Cryptococcus neoformans (Filobasidiella neoformans) Length = 303 Score = 62.5 bits (145), Expect = 1e-08 Identities = 30/68 (44%), Positives = 41/68 (60%) Frame = +3 Query: 180 PXFGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIKEGVVTREDL 359 P FGLG ++ E VK A++ GYRH+D A Y NE G+AI +K +RE++ Sbjct: 42 PQFGLGVYEMNDKETYDCVKWALEAGYRHVDTAEWYENEAPCGKAIADFLKATGTSREEI 101 Query: 360 FITSKLWN 383 F+TSKL N Sbjct: 102 FLTSKLKN 109 Score = 58.0 bits (134), Expect = 3e-07 Identities = 24/71 (33%), Positives = 37/71 (52%) Frame = +1 Query: 559 DTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLXHAXVKPVVNXVECHPYLNXKRLKEFCX 738 + WKA+ +GLVKSIGVSNF K ++ + P VN V+ HP++ + E C Sbjct: 149 NVWKALCDAQSQGLVKSIGVSNFGKKHIQEFIDQKVPLPTVNQVDLHPFMRHPEIVEICE 208 Query: 739 XRGVXIXXYSP 771 + + + P Sbjct: 209 QNEILLEAWGP 219 >UniRef50_Q5B5R6 Cluster: Putative uncharacterized protein; n=1; Emericella nidulans|Rep: Putative uncharacterized protein - Emericella nidulans (Aspergillus nidulans) Length = 682 Score = 62.5 bits (145), Expect = 1e-08 Identities = 41/96 (42%), Positives = 58/96 (60%), Gaps = 1/96 (1%) Frame = +3 Query: 174 LFPXFGLGTWKS-KPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIKEGVVTR 350 L P GLGT ++ KPG V +AV+ A+ GYRHID A G E E+G+A +K+ V+R Sbjct: 421 LIPAVGLGTRRAQKPGLVYRAVRSALKTGYRHIDTAMSSGVEHEIGQA----VKDSGVSR 476 Query: 351 EDLFITSKLWNTFHRPDLVRGALQETLEQSELSVLG 458 +++T+KL N +H +QE L+ S LS LG Sbjct: 477 SQVWVTTKLDNRWHT------RVQEALDMS-LSELG 505 >UniRef50_Q927P9 Cluster: Lin2739 protein; n=12; Bacteria|Rep: Lin2739 protein - Listeria innocua Length = 283 Score = 62.1 bits (144), Expect = 2e-08 Identities = 33/68 (48%), Positives = 43/68 (63%), Gaps = 1/68 (1%) Frame = +3 Query: 180 PXFGLGTWK-SKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIKEGVVTRED 356 P G GT++ + GE QAVK+AI GYRHID A Y NE+ VG I + V R++ Sbjct: 13 PILGFGTYQITDAGEAEQAVKEAIAAGYRHIDTAQSYMNEEAVGRGIAA----SGVDRKE 68 Query: 357 LFITSKLW 380 LFIT+K+W Sbjct: 69 LFITTKIW 76 Score = 49.2 bits (112), Expect = 1e-04 Identities = 24/74 (32%), Positives = 37/74 (50%) Frame = +1 Query: 550 DYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLXHAXVKPVVNXVECHPYLNXKRLKE 729 D W AME L +G +K+IGVSNF ++ L + P VN +E +P+ + E Sbjct: 112 DVYGAWMAMEELQAQGKIKAIGVSNFGVDRVVDLAAFNDITPQVNQIEINPFQQQSKNIE 171 Query: 730 FCXXRGVXIXXYSP 771 GV + ++P Sbjct: 172 ALRKEGVAVEAWAP 185 >UniRef50_Q64UK5 Cluster: Aldo/keto reductase family oxidoreductase; n=1; Bacteroides fragilis|Rep: Aldo/keto reductase family oxidoreductase - Bacteroides fragilis Length = 151 Score = 62.1 bits (144), Expect = 2e-08 Identities = 34/102 (33%), Positives = 52/102 (50%) Frame = +1 Query: 451 YLDLYLIHWPQAYKEDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFN 630 Y+DL LIHWP A K + W+ ME V G +++IGVSNFN Sbjct: 69 YVDLMLIHWPVARKVK--------------------ERWRIMEKYVDVGKIRAIGVSNFN 108 Query: 631 SKQLERLLXHAXVKPVVNXVECHPYLNXKRLKEFCXXRGVXI 756 ++ LL +A +KPVVN ++ HPY+ + + +G+ + Sbjct: 109 PHHVDELLAYARIKPVVNQIKIHPYMEHQEVVGNTFAKGIQV 150 Score = 39.1 bits (87), Expect = 0.15 Identities = 26/67 (38%), Positives = 35/67 (52%) Frame = +3 Query: 234 VKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIKEGVVTREDLFITSKLWNTFHRPDLVRG 413 +K AI + YR +D A Y NE EV I KE + R ++FI SK+ R VR Sbjct: 1 MKHAIGLRYRLVDAAQGYDNEAEVWYGI----KESGIGRSEVFIISKVSPDAVRSGKVRE 56 Query: 414 ALQETLE 434 +L T+E Sbjct: 57 SLDRTIE 63 >UniRef50_UPI0001556575 Cluster: PREDICTED: similar to Aldo-keto reductase family 1, member B3 (aldose reductase), partial; n=1; Ornithorhynchus anatinus|Rep: PREDICTED: similar to Aldo-keto reductase family 1, member B3 (aldose reductase), partial - Ornithorhynchus anatinus Length = 136 Score = 61.7 bits (143), Expect = 2e-08 Identities = 28/53 (52%), Positives = 36/53 (67%) Frame = +3 Query: 219 EVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIKEGVVTREDLFITSKL 377 E+T+AV A+D GYRH DCAY Y N VG+ + +I+E REDLFI SK+ Sbjct: 1 EITEAVDVALDHGYRHFDCAYFYQNAAAVGDVVRRRIEERGGRREDLFIVSKV 53 Score = 46.8 bits (106), Expect = 7e-04 Identities = 22/39 (56%), Positives = 30/39 (76%) Frame = +1 Query: 568 KAMEPLVKEGLVKSIGVSNFNSKQLERLLXHAXVKPVVN 684 +AME LV+EGLV++IGVS+FN QL+R L ++P VN Sbjct: 97 QAMERLVEEGLVRAIGVSDFNVAQLQRRLGACSIRPEVN 135 >UniRef50_Q7VHE1 Cluster: Putative uncharacterized protein; n=1; Helicobacter hepaticus|Rep: Putative uncharacterized protein - Helicobacter hepaticus Length = 270 Score = 61.7 bits (143), Expect = 2e-08 Identities = 33/95 (34%), Positives = 56/95 (58%) Frame = +3 Query: 180 PXFGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIKEGVVTREDL 359 P GLGT+ +A+ +AI++GYR D A +Y NE E+G AI + +K G + RE+ Sbjct: 13 PILGLGTYSLTGKAGQKAMSEAIEVGYRLFDSAQMYNNEAELGAAINAAVKGG-IKREEF 71 Query: 360 FITSKLWNTFHRPDLVRGALQETLEQSELSVLGSV 464 FI +KL + DL + +++++L+ L + S+ Sbjct: 72 FIQTKLLES-SSEDLAKKSIEKSLKTLGLDYIDSL 105 Score = 48.4 bits (110), Expect = 2e-04 Identities = 22/69 (31%), Positives = 36/69 (52%) Frame = +1 Query: 565 WKAMEPLVKEGLVKSIGVSNFNSKQLERLLXHAXVKPVVNXVECHPYLNXKRLKEFCXXR 744 ++AME K+G+++ IG+SNF +K + V P +N E H L K L+E + Sbjct: 118 YRAMESFYKQGILRVIGISNFGAKAYSEFVKSCEVIPAINQCETHLLLQQKPLREAMKSK 177 Query: 745 GVXIXXYSP 771 + +SP Sbjct: 178 KTLLQSWSP 186 >UniRef50_Q02198 Cluster: Morphine 6-dehydrogenase; n=5; Bacteria|Rep: Morphine 6-dehydrogenase - Pseudomonas putida Length = 296 Score = 61.7 bits (143), Expect = 2e-08 Identities = 38/111 (34%), Positives = 53/111 (47%) Frame = +1 Query: 439 LNFQYLDLYLIHWPQAYKEDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGV 618 L Y+DLYL+HWP D + IQ +WKA E ++ +G ++IGV Sbjct: 99 LGLDYVDLYLLHWPTK----------DWNATIQ--------SWKAAEKILGDGRARAIGV 140 Query: 619 SNFNSKQLERLLXHAXVKPVVNXVECHPYLNXKRLKEFCXXRGVXIXXYSP 771 NF QL+ L+ + V P VN +E HPY K L G+ +SP Sbjct: 141 CNFLEDQLDELIAASDVVPAVNQIELHPYFAQKPLLAKNRALGIVTEAWSP 191 Score = 54.8 bits (126), Expect = 3e-06 Identities = 31/84 (36%), Positives = 44/84 (52%) Frame = +3 Query: 180 PXFGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIKEGVVTREDL 359 P GLG + + E A+ AI GYR ID A Y NE +VGE I+ V R ++ Sbjct: 17 PALGLGVFAASAEETASAIASAISSGYRLIDTARSYNNEAQVGEG----IRNSGVDRAEM 72 Query: 360 FITSKLWNTFHRPDLVRGALQETL 431 F+T+KL+N + + A E+L Sbjct: 73 FVTTKLFNCDYGYERALRAFDESL 96 >UniRef50_Q6CEJ0 Cluster: Yarrowia lipolytica chromosome B of strain CLIB122 of Yarrowia lipolytica; n=1; Yarrowia lipolytica|Rep: Yarrowia lipolytica chromosome B of strain CLIB122 of Yarrowia lipolytica - Yarrowia lipolytica (Candida lipolytica) Length = 302 Score = 61.3 bits (142), Expect = 3e-08 Identities = 38/113 (33%), Positives = 54/113 (47%), Gaps = 2/113 (1%) Frame = +1 Query: 439 LNFQYLDLYLIHWPQAYKEDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGV 618 L Y DL+LIH P P D + D W +E L ++GL K+IGV Sbjct: 104 LQTDYFDLFLIHVP----------PNDDI------NYDLAKAWGVLEQLYEKGLAKAIGV 147 Query: 619 SNFNSKQLERLLXHAXVKPVVNXVECHPYLNXKR--LKEFCXXRGVXIXXYSP 771 SN + +LE ++ A +KP VN +E HP L + +FC + + YSP Sbjct: 148 SNHSPAELETIIKVAKIKPHVNQIEFHPLLQEPTPGIVDFCKQHDIVVEGYSP 200 Score = 59.3 bits (137), Expect = 1e-07 Identities = 35/69 (50%), Positives = 43/69 (62%), Gaps = 6/69 (8%) Frame = +3 Query: 186 FGLGT-WKSKPGE-----VTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIKEGVVT 347 FG GT WK PGE + AV AI+ G+ HID A YG EK++GEA IKE V Sbjct: 19 FGSGTKWKRPPGEKEERELIDAVVSAINAGHLHIDTAEFYGTEKQIGEA----IKESGVP 74 Query: 348 REDLFITSK 374 R+D+F+TSK Sbjct: 75 RKDIFLTSK 83 >UniRef50_Q5KKZ8 Cluster: Aldo-keto reductase, putative; n=2; Filobasidiella neoformans|Rep: Aldo-keto reductase, putative - Cryptococcus neoformans (Filobasidiella neoformans) Length = 293 Score = 61.3 bits (142), Expect = 3e-08 Identities = 34/90 (37%), Positives = 51/90 (56%), Gaps = 2/90 (2%) Frame = +3 Query: 174 LFPXFGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIKEGVVTRE 353 L P G G ++++ E AVK AID GYRH+D A Y NE+ VG A I+ V R Sbjct: 16 LIPRLGFGVYQARSKECEDAVKKAIDTGYRHVDTAQAYHNEENVGRA----IRNSGVPRP 71 Query: 354 DLFITSKLW--NTFHRPDLVRGALQETLEQ 437 +F+TSK +T + P V ++++L++ Sbjct: 72 SVFLTSKYMPSHTVYSPTEVLDVVRKSLKK 101 Score = 55.2 bits (127), Expect = 2e-06 Identities = 27/71 (38%), Positives = 38/71 (53%) Frame = +1 Query: 559 DTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLXHAXVKPVVNXVECHPYLNXKRLKEFCX 738 + W+A+ KEG VK IGVSNF L+ L P VN +E HP+ + + ++C Sbjct: 129 NNWEALTIAQKEGWVKDIGVSNFGIHHLKALPPPV---PAVNQIELHPFCQQRDIVKYCE 185 Query: 739 XRGVXIXXYSP 771 G+ I YSP Sbjct: 186 EHGIAIEAYSP 196 >UniRef50_Q1M4Z6 Cluster: Putative aldo-keto reductase/oxidase; n=1; Rhizobium leguminosarum bv. viciae 3841|Rep: Putative aldo-keto reductase/oxidase - Rhizobium leguminosarum bv. viciae (strain 3841) Length = 274 Score = 60.9 bits (141), Expect = 4e-08 Identities = 33/86 (38%), Positives = 48/86 (55%) Frame = +3 Query: 180 PXFGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIKEGVVTREDL 359 P G GTW E Q V A++ G RHID A YGNE++V IK+ V R ++ Sbjct: 11 PQMGYGTWNRSADEAHQGVIWALEAGCRHIDTAQGYGNEQDVARG----IKDAGVARNEI 66 Query: 360 FITSKLWNTFHRPDLVRGALQETLEQ 437 FIT+K+ + P V +++E+LE+ Sbjct: 67 FITTKVKPDNYGPGAVMPSVRESLEK 92 Score = 49.2 bits (112), Expect = 1e-04 Identities = 33/119 (27%), Positives = 53/119 (44%), Gaps = 2/119 (1%) Frame = +1 Query: 421 RRPWNNLNFQYLDLYLIHWPQAYKEDGSLFP-TDQSGKIQFSDVDYVDTWKAMEPLVKEG 597 R L +DL L+HWP + + +P D G QF++V G Sbjct: 87 RESLEKLRVDQVDLLLLHWPSPHNK----YPLADYLG--QFAEV------------FDSG 128 Query: 598 LVKSIGVSNFNSKQLERLLXHAXVKPVV-NXVECHPYLNXKRLKEFCXXRGVXIXXYSP 771 L + IGVSNF ++ + + + N VECH Y+ + + ++C G+ + YSP Sbjct: 129 LARQIGVSNFTKAMIDESIRLLDSRTITTNQVECHVYMQNRPIIDYCQNLGIAVTAYSP 187 Database: uniref50 Posted date: Oct 5, 2007 11:19 AM Number of letters in database: 575,637,011 Number of sequences in database: 1,657,284 Lambda K H 0.318 0.134 0.401 Gapped Lambda K H 0.279 0.0580 0.190 Matrix: BLOSUM62 Gap Penalties: Existence: 9, Extension: 2 Number of Hits to DB: 689,168,424 Number of Sequences: 1657284 Number of extensions: 14122058 Number of successful extensions: 47078 Number of sequences better than 10.0: 458 Number of HSP's better than 10.0 without gapping: 43279 Number of HSP's successfully gapped in prelim test: 0 Number of HSP's that attempted gapping in prelim test: 0 Number of HSP's gapped (non-prelim): 46547 length of database: 575,637,011 effective HSP length: 100 effective length of database: 409,908,611 effective search space used: 79932179145 frameshift window, decay const: 40, 0.1 T: 12 A: 40 X1: 16 ( 7.3 bits) X2: 37 (14.9 bits) X3: 62 (25.0 bits) S1: 41 (21.7 bits)
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