Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= MFBP04_F_D21
(904 letters)
Database: human
237,096 sequences; 76,859,062 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
X95648-1|CAA64950.1| 305|Homo sapiens eIF-2B protein. 74 8e-13
CR456831-1|CAG33112.1| 305|Homo sapiens EIF2B1 protein. 74 8e-13
BC104189-1|AAI04190.1| 305|Homo sapiens eukaryotic translation ... 74 8e-13
BC104188-1|AAI04189.1| 305|Homo sapiens eukaryotic translation ... 74 8e-13
BC103763-1|AAI03764.1| 305|Homo sapiens eukaryotic translation ... 74 8e-13
BC001703-1|AAH01703.1| 369|Homo sapiens hypothetical protein MG... 44 0.001
AY358176-1|AAQ88543.1| 369|Homo sapiens TLEA6390 protein. 44 0.001
BC091502-1|AAH91502.1| 523|Homo sapiens eukaryotic translation ... 41 0.007
BC001870-1|AAH01870.1| 523|Homo sapiens eukaryotic translation ... 41 0.007
AL050109-1|CAB43277.1| 394|Homo sapiens hypothetical protein pr... 41 0.007
AJ011307-2|CAB57305.1| 542|Homo sapiens guanine nucleotide exch... 41 0.007
AJ011307-1|CAB57304.1| 522|Homo sapiens guanine nucleotide exch... 41 0.007
AJ011306-1|CAB57261.1| 543|Homo sapiens guanine nucleotide exch... 41 0.007
AJ011305-1|CAB57260.1| 522|Homo sapiens guanine nucleotide exch... 41 0.007
AF112207-1|AAF17195.1| 523|Homo sapiens translation initiation ... 41 0.007
AF057699-1|AAQ13438.1| 520|Homo sapiens EIF-2B-delta-like prote... 41 0.007
AC074117-8|AAY14843.1| 522|Homo sapiens unknown protein. 41 0.007
>X95648-1|CAA64950.1| 305|Homo sapiens eIF-2B protein.
Length = 305
Score = 73.7 bits (173), Expect = 8e-13
Identities = 35/73 (47%), Positives = 47/73 (64%)
Frame = +2
Query: 641 SGEMMHXQLVAAGVDATLILXSAVGYVMEXVDIVMIGAEGVTESGGIINXIGTYSLGIXX 820
SG+ M L V T++L +AVGY+ME D+V++GAEGV E+GGIIN IGT + +
Sbjct: 160 SGKKMAKALCHLNVPVTVVLDAAVGYIMEKADLVIVGAEGVVENGGIINKIGTNQMAVCA 219
Query: 821 LXLXKPXYVLXES 859
KP YV+ ES
Sbjct: 220 KAQNKPFYVVAES 232
Score = 58.0 bits (134), Expect = 4e-08
Identities = 33/97 (34%), Positives = 53/97 (54%)
Frame = +3
Query: 351 AISSGCELFMRVYYICQIRHKEF*RM*KNYVTKR*YISGTSC*KHEGKVAKQALSFICDG 530
A+SSG ELF+R + + + ++ + K + +R + K+A +FI DG
Sbjct: 64 AVSSGGELFLRFISLASLEYSDYSKC-KKIMIERGELFLRRISLSRNKIADLCHTFIKDG 122
Query: 531 CKIXXHSRSRVVLQAMIEAIKANKRFEVFITVSAPDI 641
I H+ SRVVL+ + A+ A KRF V++T S PD+
Sbjct: 123 ATILTHAYSRVVLRVLEAAVAAKKRFSVYVTESQPDL 159
>CR456831-1|CAG33112.1| 305|Homo sapiens EIF2B1 protein.
Length = 305
Score = 73.7 bits (173), Expect = 8e-13
Identities = 35/73 (47%), Positives = 47/73 (64%)
Frame = +2
Query: 641 SGEMMHXQLVAAGVDATLILXSAVGYVMEXVDIVMIGAEGVTESGGIINXIGTYSLGIXX 820
SG+ M L V T++L +AVGY+ME D+V++GAEGV E+GGIIN IGT + +
Sbjct: 160 SGKKMAKALCHLNVPVTVVLDAAVGYIMEKADLVIVGAEGVVENGGIINKIGTNQMAVCA 219
Query: 821 LXLXKPXYVLXES 859
KP YV+ ES
Sbjct: 220 KAQNKPFYVVAES 232
Score = 58.0 bits (134), Expect = 4e-08
Identities = 33/97 (34%), Positives = 53/97 (54%)
Frame = +3
Query: 351 AISSGCELFMRVYYICQIRHKEF*RM*KNYVTKR*YISGTSC*KHEGKVAKQALSFICDG 530
A+SSG ELF+R + + + ++ + K + +R + K+A +FI DG
Sbjct: 64 AVSSGGELFLRFISLASLEYSDYSKC-KKIMIERGELFLRRISLSRNKIADLCHTFIKDG 122
Query: 531 CKIXXHSRSRVVLQAMIEAIKANKRFEVFITVSAPDI 641
I H+ SRVVL+ + A+ A KRF V++T S PD+
Sbjct: 123 ATILTHAYSRVVLRVLEAAVAAKKRFSVYVTESQPDL 159
>BC104189-1|AAI04190.1| 305|Homo sapiens eukaryotic translation
initiation factor 2B, subunit 1 alpha, 26kDa protein.
Length = 305
Score = 73.7 bits (173), Expect = 8e-13
Identities = 35/73 (47%), Positives = 47/73 (64%)
Frame = +2
Query: 641 SGEMMHXQLVAAGVDATLILXSAVGYVMEXVDIVMIGAEGVTESGGIINXIGTYSLGIXX 820
SG+ M L V T++L +AVGY+ME D+V++GAEGV E+GGIIN IGT + +
Sbjct: 160 SGKKMAKALCHLNVPVTVVLDAAVGYIMEKADLVIVGAEGVVENGGIINKIGTNQMAVCA 219
Query: 821 LXLXKPXYVLXES 859
KP YV+ ES
Sbjct: 220 KAQNKPFYVVAES 232
Score = 58.0 bits (134), Expect = 4e-08
Identities = 33/97 (34%), Positives = 53/97 (54%)
Frame = +3
Query: 351 AISSGCELFMRVYYICQIRHKEF*RM*KNYVTKR*YISGTSC*KHEGKVAKQALSFICDG 530
A+SSG ELF+R + + + ++ + K + +R + K+A +FI DG
Sbjct: 64 AVSSGGELFLRFISLASLEYSDYSKC-KKIMIERGELFLRRISLSRNKIADLCHTFIKDG 122
Query: 531 CKIXXHSRSRVVLQAMIEAIKANKRFEVFITVSAPDI 641
I H+ SRVVL+ + A+ A KRF V++T S PD+
Sbjct: 123 ATILTHAYSRVVLRVLEAAVAAKKRFSVYVTESQPDL 159
>BC104188-1|AAI04189.1| 305|Homo sapiens eukaryotic translation
initiation factor 2B, subunit 1 alpha, 26kDa protein.
Length = 305
Score = 73.7 bits (173), Expect = 8e-13
Identities = 35/73 (47%), Positives = 47/73 (64%)
Frame = +2
Query: 641 SGEMMHXQLVAAGVDATLILXSAVGYVMEXVDIVMIGAEGVTESGGIINXIGTYSLGIXX 820
SG+ M L V T++L +AVGY+ME D+V++GAEGV E+GGIIN IGT + +
Sbjct: 160 SGKKMAKALCHLNVPVTVVLDAAVGYIMEKADLVIVGAEGVVENGGIINKIGTNQMAVCA 219
Query: 821 LXLXKPXYVLXES 859
KP YV+ ES
Sbjct: 220 KAQNKPFYVVAES 232
Score = 58.0 bits (134), Expect = 4e-08
Identities = 33/97 (34%), Positives = 53/97 (54%)
Frame = +3
Query: 351 AISSGCELFMRVYYICQIRHKEF*RM*KNYVTKR*YISGTSC*KHEGKVAKQALSFICDG 530
A+SSG ELF+R + + + ++ + K + +R + K+A +FI DG
Sbjct: 64 AVSSGGELFLRFISLASLEYSDYSKC-KKIMIERGELFLRRISLSRNKIADLCHTFIKDG 122
Query: 531 CKIXXHSRSRVVLQAMIEAIKANKRFEVFITVSAPDI 641
I H+ SRVVL+ + A+ A KRF V++T S PD+
Sbjct: 123 ATILTHAYSRVVLRVLEAAVAAKKRFSVYVTESQPDL 159
>BC103763-1|AAI03764.1| 305|Homo sapiens eukaryotic translation
initiation factor 2B, subunit 1 alpha, 26kDa protein.
Length = 305
Score = 73.7 bits (173), Expect = 8e-13
Identities = 35/73 (47%), Positives = 47/73 (64%)
Frame = +2
Query: 641 SGEMMHXQLVAAGVDATLILXSAVGYVMEXVDIVMIGAEGVTESGGIINXIGTYSLGIXX 820
SG+ M L V T++L +AVGY+ME D+V++GAEGV E+GGIIN IGT + +
Sbjct: 160 SGKKMAKALCHLNVPVTVVLDAAVGYIMEKADLVIVGAEGVVENGGIINKIGTNQMAVCA 219
Query: 821 LXLXKPXYVLXES 859
KP YV+ ES
Sbjct: 220 KAQNKPFYVVAES 232
Score = 58.0 bits (134), Expect = 4e-08
Identities = 33/97 (34%), Positives = 53/97 (54%)
Frame = +3
Query: 351 AISSGCELFMRVYYICQIRHKEF*RM*KNYVTKR*YISGTSC*KHEGKVAKQALSFICDG 530
A+SSG ELF+R + + + ++ + K + +R + K+A +FI DG
Sbjct: 64 AVSSGGELFLRFISLASLEYSDYSKC-KKIMIERGELFLRRISLSRNKIADLCHTFIKDG 122
Query: 531 CKIXXHSRSRVVLQAMIEAIKANKRFEVFITVSAPDI 641
I H+ SRVVL+ + A+ A KRF V++T S PD+
Sbjct: 123 ATILTHAYSRVVLRVLEAAVAAKKRFSVYVTESQPDL 159
>BC001703-1|AAH01703.1| 369|Homo sapiens hypothetical protein
MGC3207 protein.
Length = 369
Score = 43.6 bits (98), Expect = 0.001
Identities = 31/99 (31%), Positives = 43/99 (43%), Gaps = 7/99 (7%)
Frame = +2
Query: 590 KSKQKI*SLHHSICT-----GHSGEMMHXQLVAAGVDATLILXSAVGYVM--EXVDIVMI 748
+S + L H+ CT + +LV + ATLI S V M V V++
Sbjct: 186 RSLHSLGRLEHAFCTETRPYNQGARLTAFELVYEQIPATLITDSMVAAAMAHRGVSAVVV 245
Query: 749 GAEGVTESGGIINXIGTYSLGIXXLXLXKPXYVLXESSN 865
GA+ V +G N +GTY L I P YV SS+
Sbjct: 246 GADRVVANGDTANKVGTYQLAIVAKHHGIPFYVAAPSSS 284
>AY358176-1|AAQ88543.1| 369|Homo sapiens TLEA6390 protein.
Length = 369
Score = 43.6 bits (98), Expect = 0.001
Identities = 31/99 (31%), Positives = 43/99 (43%), Gaps = 7/99 (7%)
Frame = +2
Query: 590 KSKQKI*SLHHSICT-----GHSGEMMHXQLVAAGVDATLILXSAVGYVM--EXVDIVMI 748
+S + L H+ CT + +LV + ATLI S V M V V++
Sbjct: 186 RSLHSLGRLEHAFCTETRPYNQGARLTAFELVYEQIPATLITDSMVAAAMAHRGVSAVVV 245
Query: 749 GAEGVTESGGIINXIGTYSLGIXXLXLXKPXYVLXESSN 865
GA+ V +G N +GTY L I P YV SS+
Sbjct: 246 GADRVVANGDTANKVGTYQLAIVAKHHGIPFYVAAPSSS 284
>BC091502-1|AAH91502.1| 523|Homo sapiens eukaryotic translation
initiation factor 2B, subunit 4 delta, 67kDa protein.
Length = 523
Score = 40.7 bits (91), Expect = 0.007
Identities = 21/65 (32%), Positives = 34/65 (52%)
Frame = +2
Query: 665 LVAAGVDATLILXSAVGYVMEXVDIVMIGAEGVTESGGIINXIGTYSLGIXXLXLXKPXY 844
LV AGV A+ +L A YV+ V V++GA + +G +++ +GT L + P
Sbjct: 376 LVHAGVPASYLLIPAASYVLPEVSKVLLGAHALLANGSVMSRVGTAQLALVARAHNVPVL 435
Query: 845 VLXES 859
V E+
Sbjct: 436 VCCET 440
>BC001870-1|AAH01870.1| 523|Homo sapiens eukaryotic translation
initiation factor 2B, subunit 4 delta, 67kDa protein.
Length = 523
Score = 40.7 bits (91), Expect = 0.007
Identities = 21/65 (32%), Positives = 34/65 (52%)
Frame = +2
Query: 665 LVAAGVDATLILXSAVGYVMEXVDIVMIGAEGVTESGGIINXIGTYSLGIXXLXLXKPXY 844
LV AGV A+ +L A YV+ V V++GA + +G +++ +GT L + P
Sbjct: 376 LVHAGVPASYLLIPAASYVLPEVSKVLLGAHALLANGSVMSRVGTAQLALVARAHNVPVL 435
Query: 845 VLXES 859
V E+
Sbjct: 436 VCCET 440
>AL050109-1|CAB43277.1| 394|Homo sapiens hypothetical protein
protein.
Length = 394
Score = 40.7 bits (91), Expect = 0.007
Identities = 21/65 (32%), Positives = 34/65 (52%)
Frame = +2
Query: 665 LVAAGVDATLILXSAVGYVMEXVDIVMIGAEGVTESGGIINXIGTYSLGIXXLXLXKPXY 844
LV AGV A+ +L A YV+ V V++GA + +G +++ +GT L + P
Sbjct: 247 LVHAGVPASYLLIPAASYVLPEVSKVLLGAHALLANGSVMSRVGTAQLALVARAHNVPVL 306
Query: 845 VLXES 859
V E+
Sbjct: 307 VCCET 311
>AJ011307-2|CAB57305.1| 542|Homo sapiens guanine nucleotide
exchange factor protein.
Length = 542
Score = 40.7 bits (91), Expect = 0.007
Identities = 21/65 (32%), Positives = 34/65 (52%)
Frame = +2
Query: 665 LVAAGVDATLILXSAVGYVMEXVDIVMIGAEGVTESGGIINXIGTYSLGIXXLXLXKPXY 844
LV AGV A+ +L A YV+ V V++GA + +G +++ +GT L + P
Sbjct: 395 LVHAGVPASYLLIPAASYVLPEVSKVLLGAHALLANGSVMSRVGTAQLALVARAHNVPVL 454
Query: 845 VLXES 859
V E+
Sbjct: 455 VCCET 459
>AJ011307-1|CAB57304.1| 522|Homo sapiens guanine nucleotide
exchange factor protein.
Length = 522
Score = 40.7 bits (91), Expect = 0.007
Identities = 21/65 (32%), Positives = 34/65 (52%)
Frame = +2
Query: 665 LVAAGVDATLILXSAVGYVMEXVDIVMIGAEGVTESGGIINXIGTYSLGIXXLXLXKPXY 844
LV AGV A+ +L A YV+ V V++GA + +G +++ +GT L + P
Sbjct: 375 LVHAGVPASYLLIPAASYVLPEVSKVLLGAHALLANGSVMSRVGTAQLALVARAHNVPVL 434
Query: 845 VLXES 859
V E+
Sbjct: 435 VCCET 439
>AJ011306-1|CAB57261.1| 543|Homo sapiens guanine nucleotide
exchange factor (long isoform) protein.
Length = 543
Score = 40.7 bits (91), Expect = 0.007
Identities = 21/65 (32%), Positives = 34/65 (52%)
Frame = +2
Query: 665 LVAAGVDATLILXSAVGYVMEXVDIVMIGAEGVTESGGIINXIGTYSLGIXXLXLXKPXY 844
LV AGV A+ +L A YV+ V V++GA + +G +++ +GT L + P
Sbjct: 396 LVHAGVPASYLLIPAASYVLPEVSKVLLGAHALLANGSVMSRVGTAQLALVARAHNVPVL 455
Query: 845 VLXES 859
V E+
Sbjct: 456 VCCET 460
>AJ011305-1|CAB57260.1| 522|Homo sapiens guanine nucleotide
exchange factor, delta subunit protein.
Length = 522
Score = 40.7 bits (91), Expect = 0.007
Identities = 21/65 (32%), Positives = 34/65 (52%)
Frame = +2
Query: 665 LVAAGVDATLILXSAVGYVMEXVDIVMIGAEGVTESGGIINXIGTYSLGIXXLXLXKPXY 844
LV AGV A+ +L A YV+ V V++GA + +G +++ +GT L + P
Sbjct: 375 LVHAGVPASYLLIPAASYVLPEVSKVLLGAHALLANGSVMSRVGTAQLALVARAHNVPVL 434
Query: 845 VLXES 859
V E+
Sbjct: 435 VCCET 439
>AF112207-1|AAF17195.1| 523|Homo sapiens translation initiation
factor eIF-2b delta subunit protein.
Length = 523
Score = 40.7 bits (91), Expect = 0.007
Identities = 21/65 (32%), Positives = 34/65 (52%)
Frame = +2
Query: 665 LVAAGVDATLILXSAVGYVMEXVDIVMIGAEGVTESGGIINXIGTYSLGIXXLXLXKPXY 844
LV AGV A+ +L A YV+ V V++GA + +G +++ +GT L + P
Sbjct: 376 LVHAGVPASYLLIPAASYVLPEVSKVLLGAHALLANGSVMSRVGTAQLALVARAHNVPVL 435
Query: 845 VLXES 859
V E+
Sbjct: 436 VCCET 440
>AF057699-1|AAQ13438.1| 520|Homo sapiens EIF-2B-delta-like protein
protein.
Length = 520
Score = 40.7 bits (91), Expect = 0.007
Identities = 21/65 (32%), Positives = 34/65 (52%)
Frame = +2
Query: 665 LVAAGVDATLILXSAVGYVMEXVDIVMIGAEGVTESGGIINXIGTYSLGIXXLXLXKPXY 844
LV AGV A+ +L A YV+ V V++GA + +G +++ +GT L + P
Sbjct: 373 LVHAGVPASYLLIPAASYVLPEVSKVLLGAHALLANGSVMSRVGTAQLALVARAHNVPVL 432
Query: 845 VLXES 859
V E+
Sbjct: 433 VCCET 437
>AC074117-8|AAY14843.1| 522|Homo sapiens unknown protein.
Length = 522
Score = 40.7 bits (91), Expect = 0.007
Identities = 21/65 (32%), Positives = 34/65 (52%)
Frame = +2
Query: 665 LVAAGVDATLILXSAVGYVMEXVDIVMIGAEGVTESGGIINXIGTYSLGIXXLXLXKPXY 844
LV AGV A+ +L A YV+ V V++GA + +G +++ +GT L + P
Sbjct: 375 LVHAGVPASYLLIPAASYVLPEVSKVLLGAHALLANGSVMSRVGTAQLALVARAHNVPVL 434
Query: 845 VLXES 859
V E+
Sbjct: 435 VCCET 439
Database: human
Posted date: Oct 23, 2007 1:18 PM
Number of letters in database: 76,859,062
Number of sequences in database: 237,096
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 114,036,242
Number of Sequences: 237096
Number of extensions: 2291999
Number of successful extensions: 3854
Number of sequences better than 10.0: 17
Number of HSP's better than 10.0 without gapping: 3700
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 3840
length of database: 76,859,062
effective HSP length: 90
effective length of database: 55,520,422
effective search space used: 11659288620
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
- SilkBase 1999-2023 -