Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= MFBP03_F_O16
(863 letters)
Database: uniref50
1,657,284 sequences; 575,637,011 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
UniRef50_UPI00015B605A Cluster: PREDICTED: similar to GA19489-PA... 143 4e-33
UniRef50_UPI0000DB72A4 Cluster: PREDICTED: similar to 3-phosphog... 137 4e-31
UniRef50_A7SFV8 Cluster: Predicted protein; n=1; Nematostella ve... 128 1e-28
UniRef50_O43175 Cluster: D-3-phosphoglycerate dehydrogenase; n=5... 118 2e-25
UniRef50_Q0W4A2 Cluster: D-3-phosphoglycerate dehydrogenase; n=1... 110 4e-23
UniRef50_Q3AQU0 Cluster: D-3-phosphoglycerate dehydrogenase; n=5... 109 9e-23
UniRef50_Q8R716 Cluster: Phosphoglycerate dehydrogenase and rela... 107 4e-22
UniRef50_O29445 Cluster: D-3-phosphoglycerate dehydrogenase; n=2... 107 4e-22
UniRef50_A5UQ03 Cluster: D-3-phosphoglycerate dehydrogenase; n=5... 107 5e-22
UniRef50_Q1NQ97 Cluster: D-isomer specific 2-hydroxyacid dehydro... 105 1e-21
UniRef50_Q67TJ9 Cluster: Phosphoglycerate dehydrogenase; n=1; Sy... 103 4e-21
UniRef50_Q58424 Cluster: D-3-phosphoglycerate dehydrogenase; n=7... 103 4e-21
UniRef50_A3EWA5 Cluster: Phosphoglycerate dehydrogenase; n=2; Ba... 103 8e-21
UniRef50_A0LMX1 Cluster: D-3-phosphoglycerate dehydrogenase; n=1... 102 1e-20
UniRef50_Q897N8 Cluster: D-3-phosphoglycerate dehydrogenase; n=4... 101 2e-20
UniRef50_Q9X1C1 Cluster: D-3-phosphoglycerate dehydrogenase; n=3... 101 3e-20
UniRef50_Q3ZX05 Cluster: D-3-phosphoglycerate dehydrogenase; n=3... 101 3e-20
UniRef50_O67741 Cluster: D-3-phosphoglycerate dehydrogenase; n=2... 100 4e-20
UniRef50_A7HDB1 Cluster: D-3-phosphoglycerate dehydrogenase; n=5... 99 7e-20
UniRef50_A6UQN3 Cluster: D-3-phosphoglycerate dehydrogenase; n=2... 100 9e-20
UniRef50_P73821 Cluster: D-3-phosphoglycerate dehydrogenase; n=3... 98 2e-19
UniRef50_Q8PW48 Cluster: D-3-phosphoglycerate dehydrogenase; n=4... 98 3e-19
UniRef50_Q2AHU0 Cluster: D-3-phosphoglycerate dehydrogenase; n=1... 97 7e-19
UniRef50_A2U4T1 Cluster: D-3-phosphoglycerate dehydrogenase; n=1... 97 7e-19
UniRef50_A0L7J1 Cluster: D-3-phosphoglycerate dehydrogenase; n=3... 97 7e-19
UniRef50_A1IDH6 Cluster: D-3-phosphoglycerate dehydrogenase; n=3... 95 2e-18
UniRef50_Q97ZK1 Cluster: D-3-phosphoglycerate dehydrogenase; n=4... 94 4e-18
UniRef50_A1SM51 Cluster: D-3-phosphoglycerate dehydrogenase; n=1... 94 5e-18
UniRef50_Q1AXS3 Cluster: D-3-phosphoglycerate dehydrogenase; n=1... 93 6e-18
UniRef50_Q8ZTC7 Cluster: D-3-phosphoglycerate dehydrogenase; n=5... 92 1e-17
UniRef50_Q4L766 Cluster: D-3-phosphoglycerate dehydrogenase; n=3... 91 3e-17
UniRef50_A4MA79 Cluster: D-isomer specific 2-hydroxyacid dehydro... 91 4e-17
UniRef50_UPI00015BAF48 Cluster: D-isomer specific 2-hydroxyacid ... 90 6e-17
UniRef50_Q1PZY1 Cluster: Similar to D-3-phosphoglycerate dehydro... 89 1e-16
UniRef50_O04130 Cluster: D-3-phosphoglycerate dehydrogenase, chl... 88 2e-16
UniRef50_Q1IVI0 Cluster: D-3-phosphoglycerate dehydrogenase; n=2... 88 3e-16
UniRef50_A7P9P5 Cluster: Chromosome chr3 scaffold_8, whole genom... 88 3e-16
UniRef50_Q9RUU0 Cluster: D-3-phosphoglycerate dehydrogenase; n=4... 87 4e-16
UniRef50_Q0J5C2 Cluster: Os08g0447000 protein; n=11; Viridiplant... 87 4e-16
UniRef50_A1DFM4 Cluster: D-3-phosphoglycerate dehydrogenase; n=1... 87 5e-16
UniRef50_Q8EN61 Cluster: Phosphoglycerate dehydrogenase; n=2; Ba... 86 9e-16
UniRef50_Q8YIU3 Cluster: D-3-PHOSPHOGLYCERATE DEHYDROGENASE; n=7... 85 2e-15
UniRef50_Q2LGV1 Cluster: Phosphoglycerate dehydrogenase; n=6; Ha... 85 3e-15
UniRef50_Q8TYK0 Cluster: Predicted dehydrogenase related to phos... 84 4e-15
UniRef50_Q97N23 Cluster: D-3-phosphoglycerate dehydrogenase; n=1... 84 5e-15
UniRef50_A7CYD6 Cluster: D-3-phosphoglycerate dehydrogenase; n=1... 84 5e-15
UniRef50_O33116 Cluster: D-3-phosphoglycerate dehydrogenase; n=2... 84 5e-15
UniRef50_P35136 Cluster: D-3-phosphoglycerate dehydrogenase; n=8... 84 5e-15
UniRef50_UPI0000DA2A77 Cluster: PREDICTED: similar to D-3-phosph... 83 1e-14
UniRef50_UPI0000DC0E13 Cluster: 3-phosphoglycerate dehydrogenase... 82 2e-14
UniRef50_Q6L245 Cluster: D-3-phosphoglycerate dehydrogenase; n=2... 82 2e-14
UniRef50_A6C9V4 Cluster: Phosphoglycerate dehydrogenase; n=1; Pl... 81 3e-14
UniRef50_Q7UQL2 Cluster: Phosphoglycerate dehydrogenase; n=2; Pl... 81 5e-14
UniRef50_A6C2G1 Cluster: Phosphoglycerate dehydrogenase; n=1; Pl... 81 5e-14
UniRef50_A4FIF2 Cluster: D-3-phosphoglycerate dehydrogenase; n=1... 81 5e-14
UniRef50_Q0EUV6 Cluster: D-isomer specific 2-hydroxyacid dehydro... 80 6e-14
UniRef50_A0RW58 Cluster: Phosphoglycerate dehydrogenase; n=3; Cr... 80 8e-14
UniRef50_Q81T55 Cluster: D-isomer specific 2-hydroxyacid dehydro... 79 1e-13
UniRef50_Q1K3M3 Cluster: D-3-phosphoglycerate dehydrogenase; n=1... 78 3e-13
UniRef50_A2A023 Cluster: D-3-phosphoglycerate dehydrogenase; n=2... 78 3e-13
UniRef50_Q11UL6 Cluster: Phosphoglycerate dehydrogenase; n=1; Cy... 77 6e-13
UniRef50_Q0ETU3 Cluster: D-isomer specific 2-hydroxyacid dehydro... 77 8e-13
UniRef50_Q5KN70 Cluster: D-3-phosphoglycerate dehydrogenase 2, p... 77 8e-13
UniRef50_A4ARG6 Cluster: D-3-phosphoglycerate dehydrogenase; n=1... 76 1e-12
UniRef50_A5N5A9 Cluster: SerA; n=1; Clostridium kluyveri DSM 555... 75 3e-12
UniRef50_A6Q7Q2 Cluster: D-3-phosphoglycerate dehydrogenase; n=2... 73 7e-12
UniRef50_Q0RXU8 Cluster: Phosphoglycerate dehydrogenase; n=1; Rh... 73 9e-12
UniRef50_A6EBH4 Cluster: Phosphoglycerate dehydrogenase; n=1; Pe... 73 9e-12
UniRef50_A6CKS4 Cluster: Putative uncharacterized protein; n=1; ... 73 1e-11
UniRef50_Q8XPB1 Cluster: D-3-phosphoglycerate dehydrogenase; n=3... 72 2e-11
UniRef50_A4FHH0 Cluster: D-3-phosphoglycerate dehydrogenase; n=1... 72 2e-11
UniRef50_Q5V1E2 Cluster: D-3-phosphoglycerate dehydrogenase; n=2... 71 4e-11
UniRef50_Q4LAE6 Cluster: Similar to glycerate dehydrogenase; n=1... 71 5e-11
UniRef50_Q214B1 Cluster: D-isomer specific 2-hydroxyacid dehydro... 69 1e-10
UniRef50_A7HEG1 Cluster: D-isomer specific 2-hydroxyacid dehydro... 69 1e-10
UniRef50_Q88YI0 Cluster: Phosphoglycerate dehydrogenase; n=5; Ba... 69 2e-10
UniRef50_A1JTE6 Cluster: Putative oxidoreductase; n=1; Yersinia ... 69 2e-10
UniRef50_Q49ZM5 Cluster: Putative dehydrogenase; n=1; Staphyloco... 68 3e-10
UniRef50_Q8EP33 Cluster: Glycerate dehydrogenase; n=2; Bacillace... 68 4e-10
UniRef50_Q8EMJ8 Cluster: Hypothetical conserved protein; n=1; Oc... 68 4e-10
UniRef50_A2F8V0 Cluster: D-isomer specific 2-hydroxyacid dehydro... 68 4e-10
UniRef50_Q46VE6 Cluster: D-isomer specific 2-hydroxyacid dehydro... 67 5e-10
UniRef50_Q7WM64 Cluster: Putative dehydrogenase; n=2; Bordetella... 67 6e-10
UniRef50_A6DQ00 Cluster: SerA; n=1; Lentisphaera araneosa HTCC21... 67 6e-10
UniRef50_Q03WU1 Cluster: Lactate dehydrogenase related dehydroge... 66 8e-10
UniRef50_O58320 Cluster: Glyoxylate reductase; n=16; cellular or... 66 1e-09
UniRef50_Q64UR3 Cluster: D-3-phosphoglycerate dehydrogenase; n=1... 65 2e-09
UniRef50_A1AR04 Cluster: D-isomer specific 2-hydroxyacid dehydro... 65 2e-09
UniRef50_A0VQR0 Cluster: D-isomer specific 2-hydroxyacid dehydro... 65 2e-09
UniRef50_P0A9T3 Cluster: D-3-phosphoglycerate dehydrogenase; n=1... 65 2e-09
UniRef50_Q83AZ4 Cluster: D-isomer specific 2-hydroxyacid dehydro... 65 2e-09
UniRef50_Q67M76 Cluster: Phosphoglycerate dehydrogenase, N-termi... 65 2e-09
UniRef50_A6T665 Cluster: Putative D-3-phosphoglycerate dehydroge... 64 3e-09
UniRef50_Q4WHR3 Cluster: D-3-phosphoglycerate dehydrogenase; n=1... 64 3e-09
UniRef50_Q7X388 Cluster: Phosphoglycerate dehydrogenase; n=3; Es... 64 4e-09
UniRef50_Q1V300 Cluster: D-3-phosphoglycerate dehydrogenase; n=2... 64 4e-09
UniRef50_A6PUG1 Cluster: D-isomer specific 2-hydroxyacid dehydro... 64 4e-09
UniRef50_A1HSQ7 Cluster: D-isomer specific 2-hydroxyacid dehydro... 64 4e-09
UniRef50_Q9TXJ5 Cluster: D-3-phosphoglycerate dehydrogenase-like... 64 6e-09
UniRef50_Q7D366 Cluster: AGR_pAT_578p; n=2; Agrobacterium tumefa... 63 8e-09
UniRef50_Q1FF19 Cluster: D-isomer specific 2-hydroxyacid dehydro... 63 8e-09
UniRef50_A4YUP8 Cluster: Putative D-3-phosphoglycerate dehydroge... 63 1e-08
UniRef50_Q76KF5 Cluster: D-phosphoglycerate dehydrogenase; n=2; ... 63 1e-08
UniRef50_UPI0000E4762C Cluster: PREDICTED: similar to D-3-phosph... 56 1e-08
UniRef50_Q0PQJ5 Cluster: D-isomer specific 2-hydroxyacid dehydro... 62 2e-08
UniRef50_Q0FX01 Cluster: D-isomer specific 2-hydroxyacid dehydro... 61 3e-08
UniRef50_Q5KFZ5 Cluster: Phosphoglycerate dehydrogenase, putativ... 61 4e-08
UniRef50_UPI0000D9FBAD Cluster: PREDICTED: similar to 3-phosphog... 60 5e-08
UniRef50_Q9WYG2 Cluster: Phosphoglycerate dehydrogenase, putativ... 60 5e-08
UniRef50_Q1GAM7 Cluster: D-isomer specific 2-hydroxyacid dehydro... 60 5e-08
UniRef50_A3UGW9 Cluster: D-3-phosphoglycerate dehydrogenase; n=2... 60 5e-08
UniRef50_A1RDF9 Cluster: D-isomer specific 2-hydroxyacid dehydro... 60 5e-08
UniRef50_A1HMI9 Cluster: Phosphoglycerate dehydrogenase; n=1; Th... 60 5e-08
UniRef50_Q87MN8 Cluster: Erythronate-4-phosphate dehydrogenase; ... 60 5e-08
UniRef50_A0LN07 Cluster: D-isomer specific 2-hydroxyacid dehydro... 60 7e-08
UniRef50_Q65WI5 Cluster: SerA protein; n=1; Mannheimia succinici... 60 9e-08
UniRef50_A0V9Y4 Cluster: D-isomer specific 2-hydroxyacid dehydro... 60 9e-08
UniRef50_Q8ZXX8 Cluster: D-3-phosphoglycerate dehydrogenase; n=1... 60 9e-08
UniRef50_Q3CIY1 Cluster: D-isomer specific 2-hydroxyacid dehydro... 59 1e-07
UniRef50_Q9UYH9 Cluster: D-isomer specific 2-hydroxyacid dehydro... 59 1e-07
UniRef50_Q7WEA3 Cluster: Phosphoglycerate dehydrogenase; n=1; Bo... 59 2e-07
UniRef50_Q5FUD9 Cluster: D-3-phosphoglycerate dehydrogenase; n=1... 59 2e-07
UniRef50_Q3KBX8 Cluster: D-isomer specific 2-hydroxyacid dehydro... 59 2e-07
UniRef50_A4R1I1 Cluster: Putative uncharacterized protein; n=1; ... 59 2e-07
UniRef50_Q8ECR2 Cluster: Erythronate-4-phosphate dehydrogenase; ... 59 2e-07
UniRef50_Q47XK1 Cluster: Erythronate-4-phosphate dehydrogenase; ... 59 2e-07
UniRef50_A0HBX6 Cluster: D-isomer specific 2-hydroxyacid dehydro... 58 2e-07
UniRef50_Q5QUE2 Cluster: Erythronate-4-phosphate dehydrogenase; ... 58 2e-07
UniRef50_UPI000050F9E4 Cluster: COG0111: Phosphoglycerate dehydr... 58 3e-07
UniRef50_Q8CPW2 Cluster: Glycerate dehydrogenase; n=4; Staphyloc... 58 4e-07
UniRef50_Q3SK87 Cluster: D-isomer specific 2-hydroxyacid dehydro... 58 4e-07
UniRef50_Q4AIL7 Cluster: D-isomer specific 2-hydroxyacid dehydro... 58 4e-07
UniRef50_Q18XF4 Cluster: D-isomer specific 2-hydroxyacid dehydro... 58 4e-07
UniRef50_A4WXD4 Cluster: Dimethylmenaquinone methyltransferase; ... 58 4e-07
UniRef50_A4AN91 Cluster: Predicted dehydrogenase; n=14; Bacteroi... 58 4e-07
UniRef50_Q27SN5 Cluster: Beta xylosidase-like protein; n=1; Acan... 58 4e-07
UniRef50_Q0RXQ1 Cluster: Probable phosphoglycerate dehydrogenase... 57 5e-07
UniRef50_Q82U25 Cluster: D-isomer specific 2-hydroxyacid dehydro... 57 7e-07
UniRef50_Q44NM9 Cluster: D-isomer specific 2-hydroxyacid dehydro... 57 7e-07
UniRef50_Q01W77 Cluster: D-isomer specific 2-hydroxyacid dehydro... 57 7e-07
UniRef50_A7HM61 Cluster: Glyoxylate reductase; n=1; Fervidobacte... 57 7e-07
UniRef50_A7AAD2 Cluster: Putative uncharacterized protein; n=1; ... 57 7e-07
UniRef50_Q72KT6 Cluster: Glycerate dehydrogenase/glyoxylate redu... 56 9e-07
UniRef50_Q6W1I8 Cluster: D-3-phosphoglycerate dehydrogenase; n=1... 56 9e-07
UniRef50_A3Y4H8 Cluster: Erythronate-4-phosphate dehydrogenase; ... 56 9e-07
UniRef50_A1HM37 Cluster: D-isomer specific 2-hydroxyacid dehydro... 56 9e-07
UniRef50_A0JVX0 Cluster: D-isomer specific 2-hydroxyacid dehydro... 56 9e-07
UniRef50_Q5KE95 Cluster: Phosphoglycerate dehydrogenase; n=2; Fi... 56 9e-07
UniRef50_Q6LNU2 Cluster: Erythronate-4-phosphate dehydrogenase; ... 56 9e-07
UniRef50_UPI000023EBBC Cluster: hypothetical protein FG00146.1; ... 56 1e-06
UniRef50_Q5FUW5 Cluster: D-3-phosphoglycerate dehydrogenase; n=5... 56 1e-06
UniRef50_Q21A61 Cluster: D-isomer specific 2-hydroxyacid dehydro... 56 1e-06
UniRef50_P40054 Cluster: D-3-phosphoglycerate dehydrogenase 1; n... 56 1e-06
UniRef50_UPI0000383A41 Cluster: COG1052: Lactate dehydrogenase a... 56 2e-06
UniRef50_A7BQE7 Cluster: D-3-phosphoglycerate dehydrogenase; n=1... 56 2e-06
UniRef50_A3PPC6 Cluster: D-isomer specific 2-hydroxyacid dehydro... 56 2e-06
UniRef50_Q5PCV8 Cluster: Erythronate-4-phosphate dehydrogenase; ... 56 2e-06
UniRef50_A1SW94 Cluster: Erythronate-4-phosphate dehydrogenase; ... 56 2e-06
UniRef50_Q8FPW0 Cluster: Putative uncharacterized protein; n=1; ... 55 2e-06
UniRef50_Q6A5K9 Cluster: D-isomer specific 2-hydroxyacid dehydro... 55 2e-06
UniRef50_Q5WLJ2 Cluster: D-3-phosphoglycerate dehydrogenase; n=2... 55 2e-06
UniRef50_A4ETV8 Cluster: Putative uncharacterized protein; n=6; ... 55 2e-06
UniRef50_A0ZEB8 Cluster: Predicted dehydrogenase; n=6; Cyanobact... 55 2e-06
UniRef50_Q5KQ73 Cluster: D-3-phosphoglycerate dehydrogenase, put... 55 2e-06
UniRef50_Q5AUK0 Cluster: Putative uncharacterized protein; n=1; ... 55 2e-06
UniRef50_Q0CUD5 Cluster: Putative uncharacterized protein; n=1; ... 55 2e-06
UniRef50_Q8YEC6 Cluster: Gluconate 2-dehydrogenase; n=72; Alphap... 55 3e-06
UniRef50_Q8UJZ6 Cluster: Phosphoglycerate dehydrogenase; n=3; Al... 55 3e-06
UniRef50_Q30V14 Cluster: D-isomer specific 2-hydroxyacid dehydro... 55 3e-06
UniRef50_A6UCB8 Cluster: D-isomer specific 2-hydroxyacid dehydro... 55 3e-06
UniRef50_Q6A895 Cluster: D-3-phosphoglycerate dehydrogenase; n=2... 54 4e-06
UniRef50_A1G3C5 Cluster: D-isomer specific 2-hydroxyacid dehydro... 54 4e-06
UniRef50_Q5FKH9 Cluster: Glyoxylate reductase; n=1; Lactobacillu... 54 5e-06
UniRef50_Q2BM60 Cluster: Erythronate-4-phosphate dehydrogenase; ... 54 5e-06
UniRef50_A6VXM3 Cluster: D-isomer specific 2-hydroxyacid dehydro... 54 5e-06
UniRef50_A3JX80 Cluster: D-isomer specific 2-hydroxyacid dehydro... 54 5e-06
UniRef50_A0QQ27 Cluster: Glyoxylate reductase; n=4; Mycobacteriu... 54 5e-06
UniRef50_A5N6P2 Cluster: GyaR; n=1; Clostridium kluyveri DSM 555... 54 6e-06
UniRef50_A4EAR0 Cluster: Putative uncharacterized protein; n=1; ... 54 6e-06
UniRef50_A1U1I8 Cluster: Erythronate-4-phosphate dehydrogenase; ... 54 6e-06
UniRef50_UPI000023F60F Cluster: hypothetical protein FG08018.1; ... 53 8e-06
UniRef50_Q8GQX5 Cluster: 2-oxo-4-phenylbutanoate reductase; n=2;... 53 8e-06
UniRef50_Q03YV3 Cluster: Lactate dehydrogenase related enzyme; n... 53 8e-06
UniRef50_Q3IF36 Cluster: Erythronate-4-phosphate dehydrogenase; ... 53 8e-06
UniRef50_UPI00015B49ED Cluster: PREDICTED: similar to putative g... 53 1e-05
UniRef50_Q88ZU6 Cluster: Phosphoglycerate dehydrogenase; n=2; La... 53 1e-05
UniRef50_A0UAW1 Cluster: D-isomer specific 2-hydroxyacid dehydro... 53 1e-05
UniRef50_Q2S0U3 Cluster: Erythronate-4-phosphate dehydrogenase; ... 53 1e-05
UniRef50_Q8Y3L1 Cluster: Lmo2824 protein; n=14; Bacillales|Rep: ... 52 1e-05
UniRef50_Q63VJ5 Cluster: D-3-phosphoglycerate dehydrogenase; n=8... 52 1e-05
UniRef50_A4SNU1 Cluster: Erythronate-4-phosphate dehydrogenase; ... 52 1e-05
UniRef50_Q82XE1 Cluster: D-isomer specific 2-hydroxyacid dehydro... 52 2e-05
UniRef50_A5Z3X2 Cluster: Putative uncharacterized protein; n=1; ... 52 2e-05
UniRef50_A5UPU9 Cluster: Glyoxylate reductase; n=12; Bacteria|Re... 52 2e-05
UniRef50_A1UEI9 Cluster: D-isomer specific 2-hydroxyacid dehydro... 52 2e-05
UniRef50_Q1QXV7 Cluster: Erythronate-4-phosphate dehydrogenase; ... 52 2e-05
UniRef50_Q81N95 Cluster: D-3-phosphoglycerate dehydrogenase, put... 52 2e-05
UniRef50_Q120S8 Cluster: D-isomer specific 2-hydroxyacid dehydro... 52 2e-05
UniRef50_A5URV2 Cluster: D-isomer specific 2-hydroxyacid dehydro... 52 2e-05
UniRef50_Q8MR05 Cluster: LD48009p; n=11; Coelomata|Rep: LD48009p... 52 2e-05
UniRef50_O50096 Cluster: Putative uncharacterized protein PH1388... 52 2e-05
UniRef50_A4YFM2 Cluster: D-isomer specific 2-hydroxyacid dehydro... 52 2e-05
UniRef50_Q74CK1 Cluster: Glycerate dehydrogenase; n=12; Bacteria... 51 3e-05
UniRef50_UPI00015BD3AA Cluster: UPI00015BD3AA related cluster; n... 51 4e-05
UniRef50_Q8YK31 Cluster: Glycerate dehydrogenase; n=3; Cyanobact... 51 4e-05
UniRef50_Q883D2 Cluster: D-isomer specific 2-hydroxyacid dehydro... 51 4e-05
UniRef50_A6W4F1 Cluster: D-isomer specific 2-hydroxyacid dehydro... 51 4e-05
UniRef50_A6ULR7 Cluster: D-isomer specific 2-hydroxyacid dehydro... 51 4e-05
UniRef50_A3ZMM2 Cluster: Dehydrogenase; n=1; Blastopirellula mar... 51 4e-05
UniRef50_O28495 Cluster: 2-hydroxyacid dehydrogenase, putative; ... 51 4e-05
UniRef50_Q0VQC3 Cluster: Erythronate-4-phosphate dehydrogenase; ... 51 4e-05
UniRef50_Q896Z8 Cluster: 2-hydroxyacid dehydrogenase; n=4; Clost... 50 6e-05
UniRef50_Q3DL54 Cluster: Glyoxylate reductase, NADH-dependent; n... 50 6e-05
UniRef50_Q1WVK4 Cluster: D-3-phosphoglycerate dehydrogenase; n=1... 50 6e-05
UniRef50_A7NGZ0 Cluster: D-isomer specific 2-hydroxyacid dehydro... 50 6e-05
UniRef50_A6G855 Cluster: Erythronate-4-phosphate dehydrogenase; ... 50 6e-05
UniRef50_Q4PK14 Cluster: Predicted D-isomer specific 2-hydroxyac... 50 8e-05
UniRef50_Q1MQK2 Cluster: Phosphoglycerate dehydrogenase and rela... 50 8e-05
UniRef50_Q27SS3 Cluster: Glycerate dehydrogenase-like protein; n... 50 8e-05
UniRef50_Q65DI8 Cluster: Putative uncharacterized protein; n=1; ... 50 1e-04
UniRef50_Q5ZYW9 Cluster: D-3-phosphoglycerate dehydrogenase; n=3... 50 1e-04
UniRef50_Q0FY56 Cluster: Putative phosphoglycerate dehydrogenase... 50 1e-04
UniRef50_Q9K7P7 Cluster: Glycerate dehydrogenase; n=8; Bacillace... 49 1e-04
UniRef50_Q5KYJ7 Cluster: Dehydrogenase; n=3; Firmicutes|Rep: Deh... 49 1e-04
UniRef50_Q1VRN5 Cluster: D-3-phosphoglycerate dehydrogenase; n=1... 49 1e-04
UniRef50_A6CRV0 Cluster: 2-hydroxyacid dehydrogenase; n=15; Baci... 49 1e-04
UniRef50_A5CWD1 Cluster: Erythronate-4-phosphate dehydrogenase; ... 49 1e-04
UniRef50_Q031D4 Cluster: Phosphoglycerate dehydrogenase; n=20; S... 49 2e-04
UniRef50_A6G5P3 Cluster: D-3-phosphoglycerate dehydrogenase; n=1... 49 2e-04
UniRef50_A0Z6W9 Cluster: Spermidine/putrescine ABC transporter A... 49 2e-04
UniRef50_A0Y9Y1 Cluster: Glyoxylate reductase; n=2; unclassified... 49 2e-04
UniRef50_A2D764 Cluster: D-isomer specific 2-hydroxyacid dehydro... 49 2e-04
UniRef50_Q7UQC8 Cluster: Probable 2-hydroxyacid dehydrogenase; n... 48 2e-04
UniRef50_Q1N6E5 Cluster: Erythronate-4-phosphate dehydrogenase; ... 48 2e-04
UniRef50_A1W9A3 Cluster: D-isomer specific 2-hydroxyacid dehydro... 48 2e-04
UniRef50_Q6AMI7 Cluster: Related to D-3-phosphoglycerate dehydro... 48 3e-04
UniRef50_Q49UN3 Cluster: NAD-dependent formate dehydrogenase; n=... 48 3e-04
UniRef50_Q13ZE9 Cluster: Putative dehydrogenase, D-3-phosphoglyc... 48 3e-04
UniRef50_A4SWE6 Cluster: D-isomer specific 2-hydroxyacid dehydro... 48 3e-04
UniRef50_Q3A6W9 Cluster: 3-phosphoglycerate dehydrogenase; n=1; ... 48 4e-04
UniRef50_Q04DF1 Cluster: Lactate dehydrogenase related enzyme; n... 48 4e-04
UniRef50_A4B0Y8 Cluster: Erythronate-4-phosphate dehydrogenase; ... 48 4e-04
UniRef50_Q20595 Cluster: Putative uncharacterized protein; n=3; ... 48 4e-04
UniRef50_Q8A2E4 Cluster: Erythronate-4-phosphate dehydrogenase; ... 48 4e-04
UniRef50_A4U158 Cluster: D-isomer specific 2-hydroxyacid dehydro... 47 5e-04
UniRef50_A1HQU2 Cluster: Glyoxylate reductase; n=1; Thermosinus ... 47 5e-04
UniRef50_A0GDF1 Cluster: D-isomer specific 2-hydroxyacid dehydro... 47 5e-04
UniRef50_Q4PP80 Cluster: Putative glyoxylate reductase/hydroxypy... 47 5e-04
UniRef50_P13443 Cluster: Glycerate dehydrogenase; n=15; Viridipl... 47 5e-04
UniRef50_Q89J71 Cluster: 2-hydroxyacid dehydrogenase; n=8; Brady... 47 7e-04
UniRef50_Q7MT26 Cluster: D-isomer specific 2-hydroxyacid dehydro... 47 7e-04
UniRef50_Q2S4U0 Cluster: D-isomer specific 2-hydroxyacid dehydro... 47 7e-04
UniRef50_Q1MPI0 Cluster: Lactate dehydrogenase and related dehyd... 47 7e-04
UniRef50_A7IJ69 Cluster: D-isomer specific 2-hydroxyacid dehydro... 47 7e-04
UniRef50_Q6F943 Cluster: Erythronate-4-phosphate dehydrogenase; ... 47 7e-04
UniRef50_Q9KEA4 Cluster: D-3-phosphoglycerate dehydrogenase; n=1... 46 0.001
UniRef50_Q89LI6 Cluster: Blr4558 protein; n=6; Bradyrhizobiaceae... 46 0.001
UniRef50_Q3Y1E6 Cluster: D-isomer specific 2-hydroxyacid dehydro... 46 0.001
UniRef50_Q0FF66 Cluster: Glycolate reductase; n=2; Alphaproteoba... 46 0.001
UniRef50_A7CY19 Cluster: D-isomer specific 2-hydroxyacid dehydro... 46 0.001
UniRef50_A1ZGW5 Cluster: D-3-phosphoglycerate dehydrogenase; n=1... 46 0.001
UniRef50_Q7VRU9 Cluster: Erythronate-4-phosphate dehydrogenase; ... 46 0.001
UniRef50_Q98LH4 Cluster: Phosphoglycerate dehydrogenase; n=3; Me... 46 0.001
UniRef50_Q97F10 Cluster: Possible phosphoglycerate dehydrogenase... 46 0.001
UniRef50_Q81K70 Cluster: D-isomer specific 2-hydroxyacid dehydro... 46 0.001
UniRef50_Q126C0 Cluster: D-isomer specific 2-hydroxyacid dehydro... 46 0.001
UniRef50_A6PPS4 Cluster: D-isomer specific 2-hydroxyacid dehydro... 46 0.001
UniRef50_A6C853 Cluster: D-3-phosphoglycerate dehydrogenase; n=1... 46 0.001
UniRef50_A3RV54 Cluster: 2-hydroxyacid dehydrogenase; n=5; Burkh... 46 0.001
UniRef50_A1AQ02 Cluster: D-isomer specific 2-hydroxyacid dehydro... 46 0.001
UniRef50_A0YAX4 Cluster: Phosphoglycerate dehydrogenase and rela... 46 0.001
UniRef50_A7D498 Cluster: D-isomer specific 2-hydroxyacid dehydro... 46 0.001
UniRef50_Q39LG4 Cluster: D-isomer specific 2-hydroxyacid dehydro... 46 0.002
UniRef50_P73990 Cluster: D-isomer specific 2-hydroxyacid dehydro... 46 0.002
UniRef50_Q0K073 Cluster: D-3-Phosphoglycerate dehydrogenase; n=2... 46 0.002
UniRef50_A7LVV2 Cluster: Putative uncharacterized protein; n=1; ... 46 0.002
UniRef50_A6PLZ4 Cluster: D-isomer specific 2-hydroxyacid dehydro... 46 0.002
UniRef50_A3IA61 Cluster: D-3 phosphoglycerate dehydrogenase; n=1... 46 0.002
UniRef50_A4S3N1 Cluster: Predicted protein; n=2; Ostreococcus|Re... 46 0.002
UniRef50_O69054 Cluster: Phosphonate dehydrogenase; n=16; Bacter... 46 0.002
UniRef50_Q5BU19 Cluster: Ribeye a protein; n=4; Clupeocephala|Re... 45 0.002
UniRef50_Q5HW94 Cluster: D-isomer specific 2-hydroxyacid dehydro... 45 0.002
UniRef50_Q2LUG0 Cluster: 2-hydroxyacid dehydrogenase, D-isomer s... 45 0.002
UniRef50_O86322 Cluster: POSSIBLE D-3-PHOSPHOGLYCERATE DEHYDROGE... 45 0.002
UniRef50_Q1YTV2 Cluster: Erythronate-4-phosphate dehydrogenase; ... 45 0.002
UniRef50_Q11JH0 Cluster: D-isomer specific 2-hydroxyacid dehydro... 45 0.002
UniRef50_A4FK85 Cluster: D-3-phosphoglycerate dehydrogenase, put... 45 0.002
UniRef50_A7S382 Cluster: Predicted protein; n=3; Eumetazoa|Rep: ... 45 0.002
UniRef50_A2FHI8 Cluster: D-isomer specific 2-hydroxyacid dehydro... 45 0.002
UniRef50_Q8D2P6 Cluster: Erythronate-4-phosphate dehydrogenase; ... 45 0.002
UniRef50_P56545 Cluster: C-terminal-binding protein 2; n=98; Coe... 45 0.002
UniRef50_Q8EMM3 Cluster: Dehydrogenase; n=2; cellular organisms|... 45 0.003
UniRef50_Q89EL0 Cluster: Blr7063 protein; n=1; Bradyrhizobium ja... 45 0.003
UniRef50_Q6MN05 Cluster: Phosphoglycerate dehydrogenase; n=1; Bd... 45 0.003
UniRef50_A4A3J0 Cluster: Erythronate-4-phosphate dehydrogenase; ... 45 0.003
UniRef50_Q4SJ39 Cluster: Chromosome 21 SCAF14577, whole genome s... 44 0.004
UniRef50_A0Z1V6 Cluster: Phosphoglycerate dehydrogenase and rela... 44 0.004
UniRef50_A4RX85 Cluster: Predicted protein; n=3; Ostreococcus|Re... 44 0.004
UniRef50_A2SRM1 Cluster: D-isomer specific 2-hydroxyacid dehydro... 44 0.004
UniRef50_Q31IH6 Cluster: Erythronate-4-phosphate dehydrogenase; ... 44 0.004
UniRef50_Q21LK8 Cluster: Erythronate-4-phosphate dehydrogenase; ... 44 0.004
UniRef50_Q9I3W9 Cluster: Erythronate-4-phosphate dehydrogenase; ... 44 0.004
UniRef50_Q73M93 Cluster: Glycerate dehydrogenase; n=3; Bacteria|... 44 0.005
UniRef50_Q3KAR6 Cluster: D-isomer specific 2-hydroxyacid dehydro... 44 0.005
UniRef50_Q125T3 Cluster: D-isomer specific 2-hydroxyacid dehydro... 44 0.005
UniRef50_A7HWK6 Cluster: D-isomer specific 2-hydroxyacid dehydro... 44 0.005
UniRef50_A7HBU0 Cluster: D-isomer specific 2-hydroxyacid dehydro... 44 0.005
UniRef50_A3K878 Cluster: 2-hydroxyacid dehydrogenase; n=1; Sagit... 44 0.005
UniRef50_A7P8C8 Cluster: Chromosome chr3 scaffold_8, whole genom... 44 0.005
UniRef50_Q6KZ29 Cluster: Gluconate 2-dehydrogenase; n=3; Archaea... 44 0.005
UniRef50_A4SW26 Cluster: D-isomer specific 2-hydroxyacid dehydro... 44 0.007
UniRef50_A4AL46 Cluster: Putative dehydrogenase; n=1; marine act... 44 0.007
UniRef50_A0GVM6 Cluster: D-isomer specific 2-hydroxyacid dehydro... 44 0.007
UniRef50_A0YEL9 Cluster: D-isomer specific 2-hydroxyacid dehydro... 43 0.009
UniRef50_Q4P752 Cluster: Putative uncharacterized protein; n=1; ... 43 0.009
UniRef50_A5YST2 Cluster: Phosphoglycerate dehydrogenase; n=2; Ha... 43 0.009
UniRef50_Q8F5N8 Cluster: Phosphoglycerate dehydrogenase; n=4; Le... 43 0.012
UniRef50_Q89QF5 Cluster: Blr3173 protein; n=3; Bradyrhizobium|Re... 43 0.012
UniRef50_A7CR80 Cluster: D-isomer specific 2-hydroxyacid dehydro... 43 0.012
UniRef50_A6BZW2 Cluster: Putative dehydrogenase; n=1; Planctomyc... 43 0.012
UniRef50_A3ZW64 Cluster: Phosphoglycerate dehydrogenase, putativ... 43 0.012
UniRef50_A1GFX2 Cluster: D-isomer specific 2-hydroxyacid dehydro... 43 0.012
UniRef50_Q0W672 Cluster: Glycerate dehydrogenase; n=2; Archaea|R... 43 0.012
UniRef50_P36234 Cluster: Glycerate dehydrogenase; n=2; Hyphomicr... 43 0.012
UniRef50_Q0B1Q1 Cluster: D-isomer specific 2-hydroxyacid dehydro... 42 0.015
UniRef50_A5WBM9 Cluster: D-isomer specific 2-hydroxyacid dehydro... 42 0.015
UniRef50_A5G0Z0 Cluster: D-isomer specific 2-hydroxyacid dehydro... 42 0.015
UniRef50_A4FIJ9 Cluster: D-3-phosphoglycerate dehydrogenase; n=1... 42 0.015
UniRef50_O24922 Cluster: Phosphoglycerate dehydrogenase; n=4; He... 42 0.020
UniRef50_A3PDQ1 Cluster: Putative dehydrogenase; n=1; Prochloroc... 42 0.020
UniRef50_A0QVE9 Cluster: Glyoxylate reductase; n=1; Mycobacteriu... 42 0.020
UniRef50_A1S0J0 Cluster: D-isomer specific 2-hydroxyacid dehydro... 42 0.020
UniRef50_Q7NEV2 Cluster: Phosphoglycerate dehydrogenase; n=6; Ba... 42 0.027
UniRef50_Q2S4S4 Cluster: D-3-phosphoglycerate dehydrogenase; n=1... 42 0.027
UniRef50_Q1CG62 Cluster: D-isomer specific 2-hydroxyacid dehydro... 42 0.027
UniRef50_Q12CS0 Cluster: D-isomer specific 2-hydroxyacid dehydro... 42 0.027
UniRef50_Q0FUK3 Cluster: Predicted dehydrogenase; n=3; Rhodobact... 42 0.027
UniRef50_Q9HK29 Cluster: 2-hydroxyacid dehydrogenase related pro... 42 0.027
UniRef50_UPI0000384B5F Cluster: COG0111: Phosphoglycerate dehydr... 41 0.035
UniRef50_Q7WNI7 Cluster: Putative dehydrogenase; n=1; Bordetella... 41 0.035
UniRef50_Q6F7L0 Cluster: Glycerate dehydrogenase; n=3; Gammaprot... 41 0.035
UniRef50_Q39JN8 Cluster: D-isomer specific 2-hydroxyacid dehydro... 41 0.035
UniRef50_Q8GC20 Cluster: 3-phosphoglycerate dehydrogenase; n=2; ... 41 0.035
UniRef50_A6LZ51 Cluster: D-isomer specific 2-hydroxyacid dehydro... 41 0.035
UniRef50_A4EQ78 Cluster: Dehydrogenase; n=1; Roseobacter sp. SK2... 41 0.035
UniRef50_A7EUN0 Cluster: Formate dehydrogenase; n=2; Sclerotinia... 41 0.035
UniRef50_O32264 Cluster: Probable 2-ketogluconate reductase; n=1... 41 0.035
UniRef50_Q83AR8 Cluster: Erythronate-4-phosphate dehydrogenase; ... 41 0.035
UniRef50_A6GGA6 Cluster: Probable 2-hydroxyacid dehydrogenase; n... 41 0.046
UniRef50_A1RC54 Cluster: Glyoxylate reductase; n=2; Actinomyceta... 41 0.046
UniRef50_A0HB22 Cluster: D-isomer specific 2-hydroxyacid dehydro... 41 0.046
UniRef50_A7STU0 Cluster: Predicted protein; n=5; Nematostella ve... 41 0.046
UniRef50_Q4FV16 Cluster: Erythronate-4-phosphate dehydrogenase; ... 41 0.046
UniRef50_Q579J7 Cluster: D-isomer specific 2-hydroxyacid dehydro... 40 0.061
UniRef50_Q4FNZ3 Cluster: Probable dehydrogenase; n=2; Candidatus... 40 0.061
UniRef50_Q4IV69 Cluster: D-isomer specific 2-hydroxyacid dehydro... 40 0.061
UniRef50_Q1R7K3 Cluster: 2-hydroxyacid dehydrogenase; n=7; Enter... 40 0.061
UniRef50_Q76KF6 Cluster: D-glycerate dehydrogenase; n=4; Entamoe... 40 0.061
UniRef50_Q8TR50 Cluster: Glycerate dehydrogenase; n=2; Methanosa... 40 0.061
UniRef50_A0RUD3 Cluster: 2 lactate dehydrogenase; n=2; Thermopro... 40 0.061
UniRef50_UPI0000D9E051 Cluster: PREDICTED: glyoxylate reductase/... 40 0.081
UniRef50_Q7M7Q8 Cluster: PUTATIVE D-2-HYDROXYACID DEHYDROGENASE;... 40 0.081
UniRef50_O34815 Cluster: YoaD; n=2; Bacillus|Rep: YoaD - Bacillu... 40 0.081
UniRef50_Q11AM6 Cluster: D-isomer specific 2-hydroxyacid dehydro... 40 0.081
UniRef50_A6DGS9 Cluster: Erythronate-4-phosphate dehydrogenase; ... 40 0.081
UniRef50_A4BI00 Cluster: Erythronate-4-phosphate dehydrogenase; ... 40 0.081
UniRef50_A1W7V5 Cluster: D-isomer specific 2-hydroxyacid dehydro... 40 0.081
UniRef50_A0JWH0 Cluster: D-isomer specific 2-hydroxyacid dehydro... 40 0.081
UniRef50_Q9KP72 Cluster: 2-hydroxyacid dehydrogenase family prot... 40 0.11
UniRef50_Q98GE4 Cluster: Phosphoglycerate dehydrogenase; n=5; Rh... 40 0.11
UniRef50_Q2KZD5 Cluster: Putative reductase precursor; n=1; Bord... 40 0.11
UniRef50_Q0LSC3 Cluster: D-isomer specific 2-hydroxyacid dehydro... 40 0.11
UniRef50_Q9UBQ7 Cluster: Glyoxylate reductase/hydroxypyruvate re... 40 0.11
UniRef50_Q1LCR9 Cluster: D-isomer specific 2-hydroxyacid dehydro... 39 0.14
UniRef50_A4BI79 Cluster: D-lactate dehydrogenase; n=1; Reinekea ... 39 0.14
UniRef50_A1ZX42 Cluster: Glycerate dehydrogenase; n=1; Microscil... 39 0.14
UniRef50_A0Z2L3 Cluster: Putative uncharacterized protein; n=1; ... 39 0.14
UniRef50_Q9C7T6 Cluster: Phosphoglycerate dehydrogenase, putativ... 39 0.14
UniRef50_A7PQ72 Cluster: Chromosome chr18 scaffold_24, whole gen... 39 0.14
UniRef50_A5BPF5 Cluster: Putative uncharacterized protein; n=1; ... 39 0.14
UniRef50_Q6NUX3 Cluster: Im:7137941 protein; n=3; Danio rerio|Re... 39 0.19
UniRef50_Q981W5 Cluster: Phosphoglycerate dehydrogenase; n=1; Me... 39 0.19
UniRef50_Q8EMJ4 Cluster: 2-ketogluconate reductase; n=1; Oceanob... 39 0.19
UniRef50_Q5WAF3 Cluster: 2-ketogluconate reductase; n=1; Bacillu... 39 0.19
UniRef50_Q1GJ08 Cluster: D-isomer specific 2-hydroxyacid dehydro... 39 0.19
UniRef50_A6GPV1 Cluster: D-isomer specific 2-hydroxyacid dehydro... 39 0.19
UniRef50_A0L0H4 Cluster: D-isomer specific 2-hydroxyacid dehydro... 39 0.19
UniRef50_A4R4W0 Cluster: Formate dehydrogenase; n=1; Magnaporthe... 39 0.19
UniRef50_A1D255 Cluster: Glycerate dehydrogenase; n=1; Neosartor... 39 0.19
UniRef50_Q5LQR6 Cluster: D-isomer specific 2-hydroxyacid dehydro... 38 0.25
UniRef50_Q03XJ7 Cluster: 2-hydroxyacid dehydrogenase; n=3; Lacto... 38 0.25
UniRef50_A5MYX9 Cluster: Putative uncharacterized protein; n=1; ... 38 0.25
UniRef50_A1SPF8 Cluster: D-isomer specific 2-hydroxyacid dehydro... 38 0.25
UniRef50_Q82XY9 Cluster: D-isomer specific 2-hydroxyacid dehydro... 38 0.33
UniRef50_Q5IW39 Cluster: Putative PhpE; n=2; Actinomycetales|Rep... 38 0.33
UniRef50_Q120Q8 Cluster: D-isomer specific 2-hydroxyacid dehydro... 38 0.33
UniRef50_A5IAP7 Cluster: D-isomer specific 2-hydroxyacid dehydro... 38 0.33
UniRef50_A1FGW0 Cluster: D-isomer specific 2-hydroxyacid dehydro... 38 0.33
UniRef50_Q986P2 Cluster: Phosphoglycerate dehydrogenase; n=14; c... 38 0.43
UniRef50_Q931A1 Cluster: Putative; n=2; Rhizobiales|Rep: Putativ... 38 0.43
UniRef50_Q9EXE8 Cluster: Thiamine-phosphate pyrophosphorylase; n... 38 0.43
UniRef50_A7FYM9 Cluster: D-lactate dehydrogenase; n=4; Clostridi... 38 0.43
UniRef50_A0FZA8 Cluster: D-isomer specific 2-hydroxyacid dehydro... 38 0.43
UniRef50_A5AR84 Cluster: Putative uncharacterized protein; n=1; ... 38 0.43
UniRef50_Q126V3 Cluster: D-isomer specific 2-hydroxyacid dehydro... 37 0.57
UniRef50_A4BPX8 Cluster: Glycerate dehydrogenase; n=1; Nitrococc... 37 0.57
UniRef50_Q7KT12 Cluster: CG9331-PE, isoform E; n=14; Endopterygo... 37 0.57
UniRef50_Q7MV70 Cluster: Erythronate-4-phosphate dehydrogenase; ... 37 0.57
UniRef50_UPI00015B4C72 Cluster: PREDICTED: similar to ENSANGP000... 37 0.76
UniRef50_Q5FTU6 Cluster: Putative 2-hydroxyacid dehydrogenase; n... 37 0.76
UniRef50_Q483F8 Cluster: Putative glyoxylate reductase; n=1; Col... 37 0.76
UniRef50_Q0C254 Cluster: D-isomer specific 2-hydroxyacid dehydro... 37 0.76
UniRef50_Q047V3 Cluster: Lactate dehydrogenase related 2-hydroxy... 37 0.76
UniRef50_A6UHC3 Cluster: D-isomer specific 2-hydroxyacid dehydro... 37 0.76
UniRef50_A5P5Y8 Cluster: D-isomer specific 2-hydroxyacid dehydro... 37 0.76
UniRef50_A4TF35 Cluster: D-isomer specific 2-hydroxyacid dehydro... 37 0.76
UniRef50_Q5X6I6 Cluster: Erythronate-4-phosphate dehydrogenase; ... 37 0.76
UniRef50_Q88VJ2 Cluster: D-lactate dehydrogenase; n=27; Lactobac... 37 0.76
UniRef50_A5VE25 Cluster: D-isomer specific 2-hydroxyacid dehydro... 36 1.0
UniRef50_Q0D7C9 Cluster: Os07g0264100 protein; n=5; Oryza sativa... 36 1.0
UniRef50_Q00TL2 Cluster: D-isomer specific 2-hydroxyacid dehydro... 36 1.0
UniRef50_Q17CL5 Cluster: Glyoxylate/hydroxypyruvate reductase; n... 36 1.0
UniRef50_Q8TFZ8 Cluster: Glycerate dehydrogenase, putative; n=1;... 36 1.0
UniRef50_Q5BG14 Cluster: Putative uncharacterized protein; n=1; ... 36 1.0
UniRef50_A3H6F3 Cluster: D-isomer specific 2-hydroxyacid dehydro... 36 1.0
UniRef50_Q08911 Cluster: Formate dehydrogenase 1; n=71; Eukaryot... 36 1.0
UniRef50_P44501 Cluster: 2-hydroxyacid dehydrogenase homolog; n=... 36 1.0
UniRef50_Q4S2R7 Cluster: Chromosome 17 SCAF14760, whole genome s... 36 1.3
UniRef50_Q8XN08 Cluster: D-lactate dehydrogenase; n=4; Firmicute... 36 1.3
UniRef50_Q825H6 Cluster: Putative glycerate dehydrogenase; n=1; ... 36 1.3
UniRef50_Q5LT44 Cluster: D-isomer specific 2-hydroxyacid dehydro... 36 1.3
UniRef50_A4TXP1 Cluster: Glycolate reductase; n=1; Magnetospiril... 36 1.3
UniRef50_A1WHT1 Cluster: D-isomer specific 2-hydroxyacid dehydro... 36 1.3
UniRef50_A0PVI8 Cluster: D-3-phosphoglycerate dehydrogenase SerA... 36 1.3
UniRef50_Q8LL97 Cluster: Putative uncharacterized protein; n=1; ... 36 1.3
UniRef50_Q5K657 Cluster: Hydroxyacid dehydrogenase protein Ynl27... 36 1.3
UniRef50_Q9HSS1 Cluster: Phosphoglycerate dehydrogenase; n=1; Ha... 36 1.3
UniRef50_P45250 Cluster: Putative 2-hydroxyacid dehydrogenase HI... 36 1.3
UniRef50_UPI0001553895 Cluster: PREDICTED: similar to C6orf205 p... 36 1.7
UniRef50_Q2JEY9 Cluster: Putative uncharacterized protein precur... 36 1.7
UniRef50_Q11JF3 Cluster: D-isomer specific 2-hydroxyacid dehydro... 36 1.7
UniRef50_Q04AA8 Cluster: Lactate dehydrogenase related enzyme; n... 36 1.7
UniRef50_Q9VRL7 Cluster: CG4835-PA; n=3; Eumetazoa|Rep: CG4835-P... 36 1.7
UniRef50_Q4QGK0 Cluster: Surface antigen protein 2, putative; n=... 36 1.7
UniRef50_A2EKB2 Cluster: Serine/threonine-protein kinase C, puta... 36 1.7
UniRef50_UPI0000EBEEB9 Cluster: PREDICTED: similar to C-terminal... 35 2.3
UniRef50_Q8U6W5 Cluster: 2-hydroxyacid dehydrogenase; n=3; Alpha... 35 2.3
UniRef50_Q5P4A6 Cluster: Putative uncharacterized protein; n=1; ... 35 2.3
UniRef50_Q6RK69 Cluster: D-lactate dehydrogenase; n=1; Lactobaci... 35 2.3
UniRef50_A6FZB7 Cluster: Putative dehydrogenase; n=1; Plesiocyst... 35 2.3
UniRef50_A6DBV6 Cluster: D-lactate dehydrogenase; n=1; Caminibac... 35 2.3
UniRef50_A4A9T4 Cluster: D-isomer specific 2-hydroxyacid dehydro... 35 2.3
UniRef50_Q8H423 Cluster: Putative phosphoglycerate dehydrogenase... 35 2.3
UniRef50_Q6BTY7 Cluster: Debaryomyces hansenii chromosome C of s... 35 2.3
UniRef50_O14465 Cluster: D-mandelate dehydrogenase; n=1; Rhodoto... 35 2.3
UniRef50_Q9HJV5 Cluster: Glycerate dehydrogenase related protein... 35 2.3
UniRef50_UPI0000F30951 Cluster: UPI0000F30951 related cluster; n... 35 3.1
UniRef50_Q5FUT7 Cluster: Putative uncharacterized protein; n=1; ... 35 3.1
UniRef50_Q1GWA2 Cluster: D-isomer specific 2-hydroxyacid dehydro... 35 3.1
UniRef50_A6TVU1 Cluster: D-isomer specific 2-hydroxyacid dehydro... 35 3.1
UniRef50_A5ZAJ9 Cluster: Putative uncharacterized protein; n=1; ... 35 3.1
UniRef50_A5NPP1 Cluster: Extracellular ligand-binding receptor; ... 35 3.1
UniRef50_Q00W84 Cluster: Oxidoreductase family protein; n=2; Ost... 35 3.1
UniRef50_Q7PMI6 Cluster: ENSANGP00000021069; n=1; Anopheles gamb... 35 3.1
UniRef50_Q5K7T1 Cluster: Expressed protein; n=2; Filobasidiella ... 35 3.1
UniRef50_Q6LYW5 Cluster: 2-hydroxyacid dehydrogenase, D-isomer s... 35 3.1
UniRef50_Q88YA7 Cluster: Bifunctional protein: amino acid aminot... 34 4.0
UniRef50_Q11QU3 Cluster: D-lactate dehydrogenase; n=1; Cytophaga... 34 4.0
UniRef50_A1RBK7 Cluster: Putative 2-hydroxyacid-family dehydroge... 34 4.0
UniRef50_Q9LH95 Cluster: Arabidopsis thaliana genomic DNA, chrom... 34 4.0
UniRef50_Q5KQP0 Cluster: Putative uncharacterized protein; n=1; ... 34 4.0
UniRef50_Q61GF0 Cluster: Putative uncharacterized protein CBG112... 34 4.0
UniRef50_Q55QA5 Cluster: Putative uncharacterized protein; n=2; ... 34 4.0
UniRef50_Q7W397 Cluster: Putative 2-hydroxyacid dehydrogenase; n... 34 5.3
UniRef50_Q39ST0 Cluster: Fibronectin, type III; n=1; Geobacter m... 34 5.3
UniRef50_Q2RTD0 Cluster: Glycolate reductase; n=8; Alphaproteoba... 34 5.3
UniRef50_A7CW56 Cluster: D-isomer specific 2-hydroxyacid dehydro... 34 5.3
UniRef50_A3JTB6 Cluster: Putative D-isomer specific 2-hydroxyaci... 34 5.3
UniRef50_A1GF52 Cluster: LigA precursor; n=1; Salinispora arenic... 34 5.3
UniRef50_A7BG18 Cluster: Merozoite surface protein-1; n=16; Plas... 34 5.3
UniRef50_Q6MY49 Cluster: NAD-dependant D-isomer specific 2-hydro... 34 5.3
UniRef50_Q5KKJ8 Cluster: Glyoxylate reductase, putative; n=2; Fi... 34 5.3
UniRef50_Q0UKE8 Cluster: Predicted protein; n=1; Phaeosphaeria n... 34 5.3
UniRef50_A4R2D8 Cluster: Putative uncharacterized protein; n=1; ... 34 5.3
UniRef50_Q1V097 Cluster: Phosphoglycerate dehydrogenase; n=2; Ca... 33 7.1
UniRef50_Q1M6M5 Cluster: Putative glyoxylate reductase; n=1; Rhi... 33 7.1
UniRef50_A5ZNE7 Cluster: Putative uncharacterized protein; n=1; ... 33 7.1
UniRef50_A3ZXC1 Cluster: Probable ribosomal protein S6 modificat... 33 7.1
UniRef50_Q0E4N3 Cluster: Os02g0108800 protein; n=1; Oryza sativa... 33 7.1
UniRef50_O77242 Cluster: Mucin-like protein; n=1; Heterodera gly... 33 7.1
UniRef50_A7SX46 Cluster: Predicted protein; n=2; Nematostella ve... 33 7.1
UniRef50_A7RV09 Cluster: Predicted protein; n=1; Nematostella ve... 33 7.1
UniRef50_A4RC21 Cluster: Predicted protein; n=2; Magnaporthe gri... 33 7.1
UniRef50_UPI0000587CB1 Cluster: PREDICTED: hypothetical protein;... 33 9.3
UniRef50_Q4TEV9 Cluster: Chromosome undetermined SCAF5069, whole... 33 9.3
UniRef50_Q5LSR6 Cluster: D-isomer specific 2-hydroxyacid dehydro... 33 9.3
UniRef50_A5ZQ76 Cluster: Putative uncharacterized protein; n=2; ... 33 9.3
UniRef50_A4M784 Cluster: D-isomer specific 2-hydroxyacid dehydro... 33 9.3
UniRef50_Q6Z8P7 Cluster: Putative uncharacterized protein P0708B... 33 9.3
UniRef50_Q5CUJ2 Cluster: DNA-directed RNA polymerase; n=3; Eukar... 33 9.3
>UniRef50_UPI00015B605A Cluster: PREDICTED: similar to GA19489-PA;
n=1; Nasonia vitripennis|Rep: PREDICTED: similar to
GA19489-PA - Nasonia vitripennis
Length = 511
Score = 143 bits (347), Expect = 4e-33
Identities = 66/122 (54%), Positives = 92/122 (75%)
Frame = +1
Query: 118 MVVDIKSVLIVDGVGAKCAELLNAYGIATTTKAKISKEELLMEIPNHDALVVRSATQVTK 297
M V+++SVL+ D V +CA LL ++G+ TTK K+SKEEL+ E+ HD L+VRS T+VT
Sbjct: 1 MSVNLRSVLVSDPVDERCAALLTSHGVPVTTKYKLSKEELINELQKHDGLIVRSETKVTA 60
Query: 298 EVLDAGVKLKVVGRAGAGVDNIDVXSAGKKGVGVINAPGANALSACELTCTLMLVLARHV 477
+V+ A LK+VGRAG GVDNID+ +A + G+ V+N PG N++SACELTC ++ LAR+V
Sbjct: 61 DVIAASPNLKLVGRAGTGVDNIDIPAATRNGILVLNTPGGNSVSACELTCAVISALARNV 120
Query: 478 VQ 483
VQ
Sbjct: 121 VQ 122
Score = 56.4 bits (130), Expect = 9e-07
Identities = 36/97 (37%), Positives = 47/97 (48%)
Frame = +3
Query: 516 RALYTGSELAGXXLXILGLGRVGXXVATXMYAFXMNIIGFQPFRVC*SVRPVPLHXXGAG 695
R LY G EL+G L ++G GR+G VA M AF M II + PF + + G
Sbjct: 134 RKLYAGRELSGKALGVVGFGRIGREVAHRMKAFGMEIIAYDPFFTKEQAAQIGV-TKGEL 192
Query: 696 GXFGPLTDXITLHTPVIEXTXXLYPXPMS*XQCXKGV 806
D IT+HTP+I T L + +C KGV
Sbjct: 193 EDIWKNADYITVHTPLIPQTKNLI-NATTLAKCKKGV 228
>UniRef50_UPI0000DB72A4 Cluster: PREDICTED: similar to
3-phosphoglycerate dehydrogenase; n=1; Apis
mellifera|Rep: PREDICTED: similar to 3-phosphoglycerate
dehydrogenase - Apis mellifera
Length = 478
Score = 137 bits (331), Expect = 4e-31
Identities = 68/122 (55%), Positives = 88/122 (72%)
Frame = +1
Query: 118 MVVDIKSVLIVDGVGAKCAELLNAYGIATTTKAKISKEELLMEIPNHDALVVRSATQVTK 297
M ++SVLI D V A C ELL +GI TTK K+SKE+L+ E+ NH+ L+VRS T+VT
Sbjct: 1 MSTTLRSVLISDPVDACCGELLVRHGIPVTTKYKLSKEKLIKELQNHEGLIVRSETKVTA 60
Query: 298 EVLDAGVKLKVVGRAGAGVDNIDVXSAGKKGVGVINAPGANALSACELTCTLMLVLARHV 477
+V L+VVGRAG GVDNID+ +A +KGV V+N PG N++SACELTC L+ LAR+V
Sbjct: 61 DVFACCPNLRVVGRAGTGVDNIDLEAATRKGVIVLNTPGGNSISACELTCALISNLARNV 120
Query: 478 VQ 483
Q
Sbjct: 121 TQ 122
Score = 60.9 bits (141), Expect = 4e-08
Identities = 34/98 (34%), Positives = 50/98 (51%)
Frame = +3
Query: 516 RALYTGSELAGXXLXILGLGRVGXXVATXMYAFXMNIIGFQPFRVC*SVRPVPLHXXGAG 695
R LY+G EL+G L +LG+GR+G V M A+ M +I F P + +
Sbjct: 134 RKLYSGFELSGKTLAVLGMGRIGREVTRRMQAYGMRVIAFDPLLTSEDANYLNVEKFSLD 193
Query: 696 GXFGPLTDXITLHTPVIEXTXXLYPXPMS*XQCXKGVK 809
+ P+ D IT+HTP+I T L + +C KGV+
Sbjct: 194 EIW-PMADYITVHTPLIPQTKNLI-NATTLAKCKKGVR 229
>UniRef50_A7SFV8 Cluster: Predicted protein; n=1; Nematostella
vectensis|Rep: Predicted protein - Nematostella
vectensis
Length = 487
Score = 128 bits (310), Expect = 1e-28
Identities = 61/120 (50%), Positives = 82/120 (68%)
Frame = +1
Query: 124 VDIKSVLIVDGVGAKCAELLNAYGIATTTKAKISKEELLMEIPNHDALVVRSATQVTKEV 303
+++K VLI D V + C +L G+ K+SKEEL+ EIP +D L+VRSAT+V+++V
Sbjct: 4 LELKRVLISDSVDSCCKTILERNGVTVDVNTKLSKEELVSEIPKYDGLIVRSATKVSEDV 63
Query: 304 LDAGVKLKVVGRAGAGVDNIDVXSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVQ 483
+ AG LK++GRAG GVDNID +A GV V+N PG N LSA E TC L+ LARH+ Q
Sbjct: 64 IKAGKNLKIIGRAGTGVDNIDTVAASLHGVLVMNTPGGNTLSAAEHTCALISSLARHIPQ 123
Score = 48.4 bits (110), Expect = 2e-04
Identities = 31/97 (31%), Positives = 45/97 (46%)
Frame = +3
Query: 516 RALYTGSELAGXXLXILGLGRVGXXVATXMYAFXMNIIGFQPFRVC*SVRPVPLHXXGAG 695
R + G+EL G L I+GLGR+G VA M ++ + IG+ P +
Sbjct: 135 RKQFMGNELFGKTLAIIGLGRIGREVALRMQSYGVKTIGYDPLVSPQDAAESNIEWMETE 194
Query: 696 GXFGPLTDXITLHTPVIEXTXXLYPXPMS*XQCXKGV 806
+ PL D IT+H P+I T + + C KGV
Sbjct: 195 KIW-PLADYITVHVPLIPPTKGML-NDKTIGMCKKGV 229
>UniRef50_O43175 Cluster: D-3-phosphoglycerate dehydrogenase; n=53;
Bilateria|Rep: D-3-phosphoglycerate dehydrogenase - Homo
sapiens (Human)
Length = 533
Score = 118 bits (284), Expect = 2e-25
Identities = 55/119 (46%), Positives = 84/119 (70%)
Frame = +1
Query: 127 DIKSVLIVDGVGAKCAELLNAYGIATTTKAKISKEELLMEIPNHDALVVRSATQVTKEVL 306
+++ VLI D + C ++L G+ K +SKEEL+ E+ + + L+VRSAT+VT +V+
Sbjct: 5 NLRKVLISDSLDPCCRKILQDGGLQVVEKQNLSKEELIAELQDCEGLIVRSATKVTADVI 64
Query: 307 DAGVKLKVVGRAGAGVDNIDVXSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVQ 483
+A KL+VVGRAG GVDN+D+ +A +KG+ V+N P N+LSA ELTC +++ LAR + Q
Sbjct: 65 NAAEKLQVVGRAGTGVDNVDLEAATRKGILVMNTPNGNSLSAAELTCGMIMCLARQIPQ 123
Score = 59.3 bits (137), Expect = 1e-07
Identities = 40/103 (38%), Positives = 52/103 (50%), Gaps = 5/103 (4%)
Frame = +3
Query: 516 RALYTGSELAGXXLXILGLGRVGXXVATXMYAFXMNIIGFQPF-----RVC*SVRPVPLH 680
R + G+EL G L ILGLGR+G VAT M +F M IG+ P V+ +PL
Sbjct: 135 RKKFMGTELNGKTLGILGLGRIGREVATRMQSFGMKTIGYDPIISPEVSASFGVQQLPLE 194
Query: 681 XXGAGGXFGPLTDXITLHTPVIEXTXXLYPXPMS*XQCXKGVK 809
PL D IT+HTP++ T L + QC KGV+
Sbjct: 195 ------EIWPLCDFITVHTPLLPSTTGLL-NDNTFAQCKKGVR 230
>UniRef50_Q0W4A2 Cluster: D-3-phosphoglycerate dehydrogenase; n=11;
cellular organisms|Rep: D-3-phosphoglycerate
dehydrogenase - Uncultured methanogenic archaeon RC-I
Length = 526
Score = 110 bits (265), Expect = 4e-23
Identities = 49/120 (40%), Positives = 86/120 (71%), Gaps = 1/120 (0%)
Frame = +1
Query: 139 VLIVDGVGAKCAELLNAY-GIATTTKAKISKEELLMEIPNHDALVVRSATQVTKEVLDAG 315
VL+ D + + ++L + G+ + +++KE+L+ +I +++AL++RS TQVTKEV+ AG
Sbjct: 3 VLVTDPISEEGIKILKSEPGVQVDIETRLTKEQLIEKIKDYNALIIRSETQVTKEVIAAG 62
Query: 316 VKLKVVGRAGAGVDNIDVXSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVQLHCA 495
LK++GRAG G+DN+DV +A +KG+ V NAP N ++ACE T ++ML ++R++ Q + +
Sbjct: 63 KNLKIIGRAGVGIDNVDVPAATEKGIIVANAPEGNTIAACEHTLSMMLAMSRNIPQANAS 122
Score = 41.1 bits (92), Expect = 0.035
Identities = 21/80 (26%), Positives = 36/80 (45%)
Frame = +3
Query: 516 RALYTGSELAGXXLXILGLGRVGXXVATXMYAFXMNIIGFQPFRVC*SVRPVPLHXXGAG 695
R+ + G E+ L I+GLGR+G + +F M ++ + PF + +
Sbjct: 130 RSKFMGVEVMNKTLGIIGLGRIGGEITKRARSFGMEVLAYDPFTTAERAQQIGARLTTLD 189
Query: 696 GXFGPLTDXITLHTPVIEXT 755
+ D IT+HTP+ T
Sbjct: 190 EIY-EKADFITVHTPLTPST 208
>UniRef50_Q3AQU0 Cluster: D-3-phosphoglycerate dehydrogenase; n=5;
Chlorobium/Pelodictyon group|Rep: D-3-phosphoglycerate
dehydrogenase - Chlorobium chlorochromatii (strain CaD3)
Length = 538
Score = 109 bits (262), Expect = 9e-23
Identities = 52/119 (43%), Positives = 78/119 (65%)
Frame = +1
Query: 127 DIKSVLIVDGVGAKCAELLNAYGIATTTKAKISKEELLMEIPNHDALVVRSATQVTKEVL 306
++ VLI D V +C LL +G T K +S +EL I +++ L+VRSAT + EVL
Sbjct: 11 NVMKVLITDSVHPQCGRLLLQHGFEVTEKPSLSPKELHAIIADYNILIVRSATSLPAEVL 70
Query: 307 DAGVKLKVVGRAGAGVDNIDVXSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVQ 483
+L+++GRAG GVDNID+ +A ++G+ V++ PG NA+SA E TC ++L ARH+ Q
Sbjct: 71 AKATQLELIGRAGTGVDNIDLEAATRQGIVVMSTPGGNAVSAAEHTCAMLLAAARHIPQ 129
Score = 44.4 bits (100), Expect = 0.004
Identities = 21/40 (52%), Positives = 24/40 (60%)
Frame = +3
Query: 522 LYTGSELAGXXLXILGLGRVGXXVATXMYAFXMNIIGFQP 641
LY G EL G L ++GLGRVG VA M AF M I + P
Sbjct: 143 LYAGIELEGKTLSLIGLGRVGREVAMRMQAFGMRTIAYDP 182
>UniRef50_Q8R716 Cluster: Phosphoglycerate dehydrogenase and related
dehydrogenases; n=5; Clostridia|Rep: Phosphoglycerate
dehydrogenase and related dehydrogenases -
Thermoanaerobacter tengcongensis
Length = 533
Score = 107 bits (257), Expect = 4e-22
Identities = 52/119 (43%), Positives = 80/119 (67%)
Frame = +1
Query: 139 VLIVDGVGAKCAELLNAYGIATTTKAKISKEELLMEIPNHDALVVRSATQVTKEVLDAGV 318
+++ + + + L Y K IS+EELL I ++DA++VRSAT+V +E+++ G
Sbjct: 3 IIVTEKISENGIDYLKKYA-DVDVKTNISREELLEVIKDYDAIIVRSATKVDRELIEKGE 61
Query: 319 KLKVVGRAGAGVDNIDVXSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVQLHCA 495
KLKV+GRAG GVDNIDV +A ++G+ V+N P N ++A ELT LML +AR++ Q + A
Sbjct: 62 KLKVIGRAGNGVDNIDVEAATQRGILVVNTPAGNTIAAAELTIGLMLAIARNIPQAYHA 120
Score = 41.9 bits (94), Expect = 0.020
Identities = 18/43 (41%), Positives = 27/43 (62%)
Frame = +3
Query: 516 RALYTGSELAGXXLXILGLGRVGXXVATXMYAFXMNIIGFQPF 644
R + G EL G + I+GLGR+G VA+ + AF M +I + P+
Sbjct: 128 RDRFKGVELNGKTVGIIGLGRIGSLVASRLAAFNMRVIAYDPY 170
>UniRef50_O29445 Cluster: D-3-phosphoglycerate dehydrogenase; n=2;
cellular organisms|Rep: D-3-phosphoglycerate
dehydrogenase - Archaeoglobus fulgidus
Length = 527
Score = 107 bits (257), Expect = 4e-22
Identities = 48/115 (41%), Positives = 74/115 (64%)
Frame = +1
Query: 139 VLIVDGVGAKCAELLNAYGIATTTKAKISKEELLMEIPNHDALVVRSATQVTKEVLDAGV 318
VL+ + + + + + G+ K +S+EEL+ E+P ++A+VVRS T+V EV+ A
Sbjct: 3 VLVAEPISEEAIDYMRKNGLEVEVKTGMSREELIREVPKYEAIVVRSQTKVDAEVIQAAK 62
Query: 319 KLKVVGRAGAGVDNIDVXSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVQ 483
LK++GRAG GVDNID+ +A ++G+ V+NAPG N +S E LML AR + Q
Sbjct: 63 NLKIIGRAGVGVDNIDINAATQRGIVVVNAPGGNTISTAEHAIALMLAAARKIPQ 117
Score = 40.3 bits (90), Expect = 0.061
Identities = 18/43 (41%), Positives = 24/43 (55%)
Frame = +3
Query: 516 RALYTGSELAGXXLXILGLGRVGXXVATXMYAFXMNIIGFQPF 644
R + G EL G ++GLGRVG VA A MN++ + PF
Sbjct: 129 RKKFMGIELRGKTAGVIGLGRVGFEVAKRCKALEMNVLAYDPF 171
>UniRef50_A5UQ03 Cluster: D-3-phosphoglycerate dehydrogenase; n=5;
Chloroflexi (class)|Rep: D-3-phosphoglycerate
dehydrogenase - Roseiflexus sp. RS-1
Length = 524
Score = 107 bits (256), Expect = 5e-22
Identities = 49/93 (52%), Positives = 70/93 (75%)
Frame = +1
Query: 211 KAKISKEELLMEIPNHDALVVRSATQVTKEVLDAGVKLKVVGRAGAGVDNIDVXSAGKKG 390
+ + K L+ +P +DAL+VRSAT+VT EVL AG +L+VVGRAG GVDNID+ +A ++G
Sbjct: 27 RTDLDKAGLIAILPEYDALIVRSATRVTAEVLAAGTRLRVVGRAGTGVDNIDLEAATRQG 86
Query: 391 VGVINAPGANALSACELTCTLMLVLARHVVQLH 489
+ V+NAP +N+++ ELT L+L LARH+ Q H
Sbjct: 87 IMVVNAPASNSVAVAELTIALILSLARHIPQAH 119
Score = 34.3 bits (75), Expect = 4.0
Identities = 25/86 (29%), Positives = 39/86 (45%), Gaps = 6/86 (6%)
Frame = +3
Query: 516 RALYTGSELAGXXLXILGLGRVGXXVATXMYAFXMNIIGFQPFRVC*SVRPVPLHXXGAG 695
R + G E+ L ++GLGR+G VA M+++ + P V + R L G
Sbjct: 129 RNRFMGFEVRNKTLGLVGLGRIGAEVARRARGLEMHVVAYDP--VVSTERAAQL-----G 181
Query: 696 GXFGPL------TDXITLHTPVIEXT 755
PL D ++LH P+I+ T
Sbjct: 182 ATLAPLEEVLAQADIVSLHVPLIDAT 207
>UniRef50_Q1NQ97 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase, catalytic region:D- isomer specific
2-hydroxyacid dehydrogenase, NAD-binding; n=2;
Bacteria|Rep: D-isomer specific 2-hydroxyacid
dehydrogenase, catalytic region:D- isomer specific
2-hydroxyacid dehydrogenase, NAD-binding - delta
proteobacterium MLMS-1
Length = 304
Score = 105 bits (252), Expect = 1e-21
Identities = 52/115 (45%), Positives = 76/115 (66%)
Frame = +1
Query: 139 VLIVDGVGAKCAELLNAYGIATTTKAKISKEELLMEIPNHDALVVRSATQVTKEVLDAGV 318
VLI D + +++ G+ + +S EEL+ IP +D LV+RSA++VT E+L+A
Sbjct: 3 VLISDNLAPVGEKIMRDAGLEVDVRTGLSPEELVKIIPAYDGLVIRSASKVTAEILEAAE 62
Query: 319 KLKVVGRAGAGVDNIDVXSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVQ 483
LKVVGRAG G+DN+DV +A KKGV V+NAP NA +A E ++M+ L R++ Q
Sbjct: 63 NLKVVGRAGIGLDNVDVPAASKKGVVVMNAPDGNATTAAEHAVSMMMALTRNIPQ 117
>UniRef50_Q67TJ9 Cluster: Phosphoglycerate dehydrogenase; n=1;
Symbiobacterium thermophilum|Rep: Phosphoglycerate
dehydrogenase - Symbiobacterium thermophilum
Length = 540
Score = 103 bits (248), Expect = 4e-21
Identities = 51/93 (54%), Positives = 66/93 (70%)
Frame = +1
Query: 217 KISKEELLMEIPNHDALVVRSATQVTKEVLDAGVKLKVVGRAGAGVDNIDVXSAGKKGVG 396
K++ EELL IP +DAL+ RS T+VT EVL G +LKVVGRAG GVDNIDV +A ++GV
Sbjct: 27 KVTSEELLEIIPEYDALITRSETKVTAEVLARGTRLKVVGRAGVGVDNIDVAAATERGVV 86
Query: 397 VINAPGANALSACELTCTLMLVLARHVVQLHCA 495
V+N PGAN S E L++ +AR++ Q H A
Sbjct: 87 VVNVPGANTYSTAEHAFGLLIAVARNIPQAHHA 119
Score = 42.7 bits (96), Expect = 0.012
Identities = 18/43 (41%), Positives = 26/43 (60%)
Frame = +3
Query: 516 RALYTGSELAGXXLXILGLGRVGXXVATXMYAFXMNIIGFQPF 644
R + G+EL G L I+GLGR+G VA AF M ++ + P+
Sbjct: 128 RMSFVGTELHGKTLGIIGLGRIGSEVAVRARAFGMRVLAYDPY 170
>UniRef50_Q58424 Cluster: D-3-phosphoglycerate dehydrogenase; n=7;
Euryarchaeota|Rep: D-3-phosphoglycerate dehydrogenase -
Methanococcus jannaschii
Length = 524
Score = 103 bits (248), Expect = 4e-21
Identities = 53/115 (46%), Positives = 77/115 (66%)
Frame = +1
Query: 139 VLIVDGVGAKCAELLNAYGIATTTKAKISKEELLMEIPNHDALVVRSATQVTKEVLDAGV 318
+L+ D + ++L G ++KEELL +I + D LVVRS T+VT++V++
Sbjct: 4 ILVTDPLHEDAIKILEEVGEVEVATG-LTKEELLEKIKDADVLVVRSGTKVTRDVIEKAE 62
Query: 319 KLKVVGRAGAGVDNIDVXSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVQ 483
KLKV+GRAG GVDNIDV +A +KG+ V+NAP A+++S ELT LML AR++ Q
Sbjct: 63 KLKVIGRAGVGVDNIDVEAATEKGIIVVNAPDASSISVAELTMGLMLAAARNIPQ 117
Score = 47.2 bits (107), Expect = 5e-04
Identities = 31/95 (32%), Positives = 42/95 (44%)
Frame = +3
Query: 471 PRGPASLR*XLAGGXRALYTGSELAGXXLXILGLGRVGXXVATXMYAFXMNIIGFQPFRV 650
P+ ASL+ R + G EL G L ++GLGR+G V AF MNIIG+ P+
Sbjct: 116 PQATASLK--RGEWDRKRFKGIELYGKTLGVIGLGRIGQQVVKRAKAFGMNIIGYDPYIP 173
Query: 651 C*SVRPVPLHXXGAGGXFGPLTDXITLHTPVIEXT 755
+ + D ITLH P+ T
Sbjct: 174 KEVAESMGVELVDDINELCKRADFITLHVPLTPKT 208
>UniRef50_A3EWA5 Cluster: Phosphoglycerate dehydrogenase; n=2;
Bacteria|Rep: Phosphoglycerate dehydrogenase -
Leptospirillum sp. Group II UBA
Length = 535
Score = 103 bits (246), Expect = 8e-21
Identities = 49/126 (38%), Positives = 79/126 (62%)
Frame = +1
Query: 118 MVVDIKSVLIVDGVGAKCAELLNAYGIATTTKAKISKEELLMEIPNHDALVVRSATQVTK 297
M DI+ +LI D + + G K K+S +EL EI +D LV+RS T+VT+
Sbjct: 1 MSSDIR-ILISDAISEDGVRIFQKAGFHVDMKTKLSPQELAQEISQYDGLVIRSGTKVTR 59
Query: 298 EVLDAGVKLKVVGRAGAGVDNIDVXSAGKKGVGVINAPGANALSACELTCTLMLVLARHV 477
E+L +LKV+GRAGAG+DN+D+ +A ++G+ V+N PG N ++ E T +L++ +AR +
Sbjct: 60 EILKNADRLKVIGRAGAGLDNVDLEAATERGIVVMNTPGGNTVTTAEHTMSLLMSMARRI 119
Query: 478 VQLHCA 495
Q + +
Sbjct: 120 PQANAS 125
Score = 42.7 bits (96), Expect = 0.012
Identities = 26/83 (31%), Positives = 37/83 (44%)
Frame = +3
Query: 516 RALYTGSELAGXXLXILGLGRVGXXVATXMYAFXMNIIGFQPFRVC*SVRPVPLHXXGAG 695
++ + G EL L I+G+G++G VA MNII F P+ +H
Sbjct: 133 KSKFMGVELFQKTLGIVGMGKIGQHVAQIARGIAMNIIAFDPYLTPEVAEKSGVHPVSLD 192
Query: 696 GXFGPLTDXITLHTPVIEXTXXL 764
F D IT+HTP+ T L
Sbjct: 193 ELF-QRADFITVHTPLTPETTGL 214
>UniRef50_A0LMX1 Cluster: D-3-phosphoglycerate dehydrogenase; n=1;
Syntrophobacter fumaroxidans MPOB|Rep:
D-3-phosphoglycerate dehydrogenase - Syntrophobacter
fumaroxidans (strain DSM 10017 / MPOB)
Length = 525
Score = 102 bits (245), Expect = 1e-20
Identities = 53/116 (45%), Positives = 75/116 (64%), Gaps = 1/116 (0%)
Frame = +1
Query: 139 VLIVDGVGAKCAELLNAY-GIATTTKAKISKEELLMEIPNHDALVVRSATQVTKEVLDAG 315
VLI DG+ +L A GI + EE+ +P++DA++VRS T++T E+++
Sbjct: 3 VLICDGMHEVGLSILRAAEGIDVDVPDQPGAEEIKAMLPDYDAVIVRSRTRITAELIENA 62
Query: 316 VKLKVVGRAGAGVDNIDVXSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVQ 483
+LKV+GRAG GVDNIDV +A +G V+N PGANA +A E T +ML LARH+ Q
Sbjct: 63 PRLKVIGRAGTGVDNIDVKAASARGALVMNTPGANATAAAEHTIAMMLALARHIPQ 118
Score = 37.1 bits (82), Expect = 0.57
Identities = 21/77 (27%), Positives = 37/77 (48%)
Frame = +3
Query: 525 YTGSELAGXXLXILGLGRVGXXVATXMYAFXMNIIGFQPFRVC*SVRPVPLHXXGAGGXF 704
+ G+EL L I+GLG++G VA + M+++G P+ + + + +
Sbjct: 133 FMGTELFHQTLGIIGLGKIGSIVADRALSMKMDVLGHDPYIIPEAAAILGVEWVPLDELL 192
Query: 705 GPLTDXITLHTPVIEXT 755
+D +TLHTP T
Sbjct: 193 A-RSDFLTLHTPSTSET 208
>UniRef50_Q897N8 Cluster: D-3-phosphoglycerate dehydrogenase; n=4;
Clostridiales|Rep: D-3-phosphoglycerate dehydrogenase -
Clostridium tetani
Length = 533
Score = 101 bits (242), Expect = 2e-20
Identities = 52/121 (42%), Positives = 76/121 (62%), Gaps = 1/121 (0%)
Frame = +1
Query: 124 VDIKSVLIVDGVGAKCAELLNAY-GIATTTKAKISKEELLMEIPNHDALVVRSATQVTKE 300
+D +LIVD + K ELL + K + +E+LL I N+D L++RS T + E
Sbjct: 1 MDKAKILIVDKIDTKGIELLESEPNFEVDIKMGLEREKLLNIIENYDGLIIRSDTNIDIE 60
Query: 301 VLDAGVKLKVVGRAGAGVDNIDVXSAGKKGVGVINAPGANALSACELTCTLMLVLARHVV 480
+++ KLKVVGRAG GVDNID+ A K+G+ V N P +N +SACELT L+L +R++
Sbjct: 61 LMNMAKKLKVVGRAGNGVDNIDIPEATKRGIIVANTPDSNTISACELTIGLLLAQSRNIA 120
Query: 481 Q 483
+
Sbjct: 121 K 121
Score = 48.0 bits (109), Expect = 3e-04
Identities = 28/80 (35%), Positives = 39/80 (48%)
Frame = +3
Query: 516 RALYTGSELAGXXLXILGLGRVGXXVATXMYAFXMNIIGFQPFRVC*SVRPVPLHXXGAG 695
R + G+EL L I+GLGR+G VAT M AF M +I + P+ + +
Sbjct: 133 RDSFMGTELFNKTLGIIGLGRIGSLVATRMNAFDMKVIAYDPYISDERFKRFNVEKKDTL 192
Query: 696 GXFGPLTDXITLHTPVIEXT 755
+D IT+HTP E T
Sbjct: 193 EDLLKESDFITIHTPRTEET 212
>UniRef50_Q9X1C1 Cluster: D-3-phosphoglycerate dehydrogenase; n=3;
Thermotogaceae|Rep: D-3-phosphoglycerate dehydrogenase -
Thermotoga maritima
Length = 306
Score = 101 bits (241), Expect = 3e-20
Identities = 51/115 (44%), Positives = 72/115 (62%)
Frame = +1
Query: 139 VLIVDGVGAKCAELLNAYGIATTTKAKISKEELLMEIPNHDALVVRSATQVTKEVLDAGV 318
V + D + + +LL T + K+EL+ IP D LVVRSAT+VT ++++AG
Sbjct: 6 VHVNDPLDKEATQLLMNKEELEVTSEHLEKDELMKIIPEVDVLVVRSATKVTADIIEAGK 65
Query: 319 KLKVVGRAGAGVDNIDVXSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVQ 483
LK++ RAG G+DNIDV A +KG+ V+N PGA+A S EL LML ARH+ +
Sbjct: 66 NLKIIARAGIGLDNIDVQKAKEKGIKVLNTPGASAPSVAELAMGLMLACARHIAR 120
>UniRef50_Q3ZX05 Cluster: D-3-phosphoglycerate dehydrogenase; n=3;
Dehalococcoides|Rep: D-3-phosphoglycerate dehydrogenase
- Dehalococcoides sp. (strain CBDB1)
Length = 526
Score = 101 bits (241), Expect = 3e-20
Identities = 53/116 (45%), Positives = 73/116 (62%)
Frame = +1
Query: 130 IKSVLIVDGVGAKCAELLNAYGIATTTKAKISKEELLMEIPNHDALVVRSATQVTKEVLD 309
+K VL+ D + A L K + EEL+ I +DAL+VRS TQVT ++++
Sbjct: 1 MKKVLVSDALSATGLAPLKEIA-QVDVKTGLKPEELISIIGEYDALLVRSQTQVTADIIN 59
Query: 310 AGVKLKVVGRAGAGVDNIDVXSAGKKGVGVINAPGANALSACELTCTLMLVLARHV 477
AG KL+V+GRAG GVDNID+ +A G+ V+NAP N +SA E T LML +ARH+
Sbjct: 60 AGKKLQVIGRAGVGVDNIDLKTATGNGIIVVNAPTGNTISATEHTLALMLAMARHI 115
Score = 46.0 bits (104), Expect = 0.001
Identities = 32/98 (32%), Positives = 43/98 (43%)
Frame = +3
Query: 471 PRGPASLR*XLAGGXRALYTGSELAGXXLXILGLGRVGXXVATXMYAFXMNIIGFQPFRV 650
PR ASL+ R + GSEL G L I+GLG +G +A A M +IG+ PF
Sbjct: 116 PRANASLK--SGQWKRNEFVGSELKGKTLGIVGLGNIGSEIAKRALALEMRVIGYDPFIS 173
Query: 651 C*SVRPVPLHXXGAGGXFGPLTDXITLHTPVIEXTXXL 764
+ + + D ITLH P+ T L
Sbjct: 174 MERAKKLQVELLPFEDLL-KRADFITLHVPMTGQTKGL 210
>UniRef50_O67741 Cluster: D-3-phosphoglycerate dehydrogenase; n=2;
Aquifex aeolicus|Rep: D-3-phosphoglycerate dehydrogenase
- Aquifex aeolicus
Length = 533
Score = 100 bits (240), Expect = 4e-20
Identities = 55/118 (46%), Positives = 73/118 (61%), Gaps = 1/118 (0%)
Frame = +1
Query: 139 VLIVDGVGAKCAELLNAYG-IATTTKAKISKEELLMEIPNHDALVVRSATQVTKEVLDAG 315
VLI D + + ELL + + IS EELL I + DA++ RS T VTKE+L+
Sbjct: 4 VLITDPIAPEGIELLQKDPEVEVYNEPDISYEELLEIIKDFDAIITRSRTPVTKELLERA 63
Query: 316 VKLKVVGRAGAGVDNIDVXSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVQLH 489
KLKVVGRAG GVDN+D+ A K+G+ V+N PGAN + A ELT ML + R+ + H
Sbjct: 64 EKLKVVGRAGVGVDNVDIEEATKRGILVVNTPGANTIGATELTMMHMLTIMRNGHKAH 121
>UniRef50_A7HDB1 Cluster: D-3-phosphoglycerate dehydrogenase; n=5;
Proteobacteria|Rep: D-3-phosphoglycerate dehydrogenase -
Anaeromyxobacter sp. Fw109-5
Length = 528
Score = 99 bits (238), Expect = 7e-20
Identities = 44/116 (37%), Positives = 75/116 (64%)
Frame = +1
Query: 130 IKSVLIVDGVGAKCAELLNAYGIATTTKAKISKEELLMEIPNHDALVVRSATQVTKEVLD 309
+ VL+ D + + +L G+ K + ++L + ++D L VRSAT+VT ++LD
Sbjct: 2 VARVLVSDDLSPEAVRILQEAGLEVDVKVGLKPDQLERIVGDYDGLAVRSATKVTAQLLD 61
Query: 310 AGVKLKVVGRAGAGVDNIDVXSAGKKGVGVINAPGANALSACELTCTLMLVLARHV 477
+LKV+GRAG GVDN+D+ +A ++GV V+N PG ++++ EL +++L L+RHV
Sbjct: 62 KAARLKVIGRAGVGVDNVDLAAATRRGVVVMNTPGGSSITVAELALSMILALSRHV 117
Score = 37.5 bits (83), Expect = 0.43
Identities = 14/40 (35%), Positives = 22/40 (55%)
Frame = +3
Query: 525 YTGSELAGXXLXILGLGRVGXXVATXMYAFXMNIIGFQPF 644
+ G ELAG L ++G+G +G + A M ++ F PF
Sbjct: 134 FQGHELAGRTLGVVGIGNIGSVLVARAVALGMRVVAFDPF 173
>UniRef50_A6UQN3 Cluster: D-3-phosphoglycerate dehydrogenase; n=2;
Methanococcus|Rep: D-3-phosphoglycerate dehydrogenase -
Methanococcus vannielii SB
Length = 523
Score = 99.5 bits (237), Expect = 9e-20
Identities = 54/115 (46%), Positives = 73/115 (63%)
Frame = +1
Query: 139 VLIVDGVGAKCAELLNAYGIATTTKAKISKEELLMEIPNHDALVVRSATQVTKEVLDAGV 318
+LI D + E+L G IS EE+ +I + DALVVRS T VTKE++DA
Sbjct: 4 ILITDPLHESAIEILKEAGEVEIATG-ISIEEIKQKIKDADALVVRSGTTVTKEIIDASE 62
Query: 319 KLKVVGRAGAGVDNIDVXSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVQ 483
LKV+ RAG GVDN+D+ +A +KGV V+NAP A+++S EL LML AR++ Q
Sbjct: 63 NLKVIARAGVGVDNVDLDAATEKGVVVVNAPDASSISVAELMFGLMLSAARNIPQ 117
Score = 41.1 bits (92), Expect = 0.035
Identities = 22/58 (37%), Positives = 31/58 (53%)
Frame = +3
Query: 471 PRGPASLR*XLAGGXRALYTGSELAGXXLXILGLGRVGXXVATXMYAFXMNIIGFQPF 644
P+ ASL+ R + G E+ L I+GLGR+G VA AF MNI+ + P+
Sbjct: 116 PQATASLK--KGEWDRKSFKGMEVYAKTLGIVGLGRIGQQVAKRAQAFEMNIVAYDPY 171
>UniRef50_P73821 Cluster: D-3-phosphoglycerate dehydrogenase; n=37;
Cyanobacteria|Rep: D-3-phosphoglycerate dehydrogenase -
Synechocystis sp. (strain PCC 6803)
Length = 554
Score = 98.3 bits (234), Expect = 2e-19
Identities = 44/113 (38%), Positives = 76/113 (67%)
Frame = +1
Query: 139 VLIVDGVGAKCAELLNAYGIATTTKAKISKEELLMEIPNHDALVVRSATQVTKEVLDAGV 318
VL+ D + ++L K +S+ E++ +P +DA+++RSAT+VT++++ AG
Sbjct: 32 VLVSDSIDQVGIDILKQVA-QVDVKTGLSEAEIIDIVPEYDAIMLRSATKVTEKIIQAGS 90
Query: 319 KLKVVGRAGAGVDNIDVXSAGKKGVGVINAPGANALSACELTCTLMLVLARHV 477
+LK++GRAG GVDNIDV +A ++G+ V+N+P N ++A E +M+ LARH+
Sbjct: 91 QLKIIGRAGVGVDNIDVPAATRQGIVVVNSPEGNTIAAAEHALAMMMALARHI 143
Score = 33.5 bits (73), Expect = 7.1
Identities = 14/43 (32%), Positives = 24/43 (55%)
Frame = +3
Query: 516 RALYTGSELAGXXLXILGLGRVGXXVATXMYAFXMNIIGFQPF 644
R + G+E+ L ++GLG++G VA A M ++ + PF
Sbjct: 157 RKQFIGTEVYKKTLGVVGLGKIGSHVAGVAKAMGMKLLAYDPF 199
>UniRef50_Q8PW48 Cluster: D-3-phosphoglycerate dehydrogenase; n=4;
Methanomicrobia|Rep: D-3-phosphoglycerate dehydrogenase
- Methanosarcina mazei (Methanosarcina frisia)
Length = 540
Score = 97.9 bits (233), Expect = 3e-19
Identities = 49/124 (39%), Positives = 81/124 (65%)
Frame = +1
Query: 124 VDIKSVLIVDGVGAKCAELLNAYGIATTTKAKISKEELLMEIPNHDALVVRSATQVTKEV 303
+D+K VL+ D + + E+L + + ++EL+ +I +DALV+RS TQVT+ +
Sbjct: 16 IDMK-VLVSDSLSNEGLEILKEH-FDIDVCTGLCEDELVEKIKGYDALVIRSGTQVTQRI 73
Query: 304 LDAGVKLKVVGRAGAGVDNIDVXSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVQ 483
++A LK++GRAG GVDN+DV +A KKG+ V NAP N +SA E T +M+ ++R++ Q
Sbjct: 74 IEAADNLKIIGRAGVGVDNVDVDAATKKGIIVANAPEGNMISAAEHTIAMMMSMSRNIPQ 133
Query: 484 LHCA 495
+ +
Sbjct: 134 ANAS 137
Score = 44.8 bits (101), Expect = 0.003
Identities = 28/81 (34%), Positives = 40/81 (49%), Gaps = 1/81 (1%)
Frame = +3
Query: 516 RALYTGSELAGXXLXILGLGRVGXXVATXMYAFXMNIIGFQPFRVC*SVRPVPLHXXGAG 695
R + G E+ G L ++GLGR+G VA MN++G+ PF R + L A
Sbjct: 145 RNKFMGVEVKGKTLGVIGLGRIGSEVAKRAAGLEMNLMGYDPF--ISEKRAMELGVKLAT 202
Query: 696 -GXFGPLTDXITLHTPVIEXT 755
D IT+HTP+I+ T
Sbjct: 203 VNEIAKEADYITVHTPLIKET 223
>UniRef50_Q2AHU0 Cluster: D-3-phosphoglycerate dehydrogenase; n=1;
Halothermothrix orenii H 168|Rep: D-3-phosphoglycerate
dehydrogenase - Halothermothrix orenii H 168
Length = 527
Score = 96.7 bits (230), Expect = 7e-19
Identities = 52/119 (43%), Positives = 70/119 (58%)
Frame = +1
Query: 139 VLIVDGVGAKCAELLNAYGIATTTKAKISKEELLMEIPNHDALVVRSATQVTKEVLDAGV 318
VL+ D + K E+L T +S+EE L I +D L+VRS T+V KE LD
Sbjct: 4 VLVSDNISPKGIEILEQEA-DVTFNPDLSREEFLDIIGEYDGLIVRSMTEVDKEALDKAR 62
Query: 319 KLKVVGRAGAGVDNIDVXSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVQLHCA 495
LKV+GRAG G DNID+ A K+G+ V N P N +SA E T +ML L+R++ Q + A
Sbjct: 63 NLKVIGRAGTGYDNIDIEEASKRGIIVFNTPTGNTISAVEHTIGMMLALSRNIPQANQA 121
Score = 46.8 bits (106), Expect = 7e-04
Identities = 28/80 (35%), Positives = 38/80 (47%)
Frame = +3
Query: 516 RALYTGSELAGXXLXILGLGRVGXXVATXMYAFXMNIIGFQPFRVC*SVRPVPLHXXGAG 695
R Y G E+ G L I+GLGR+G VA AF M +I P+ + + G
Sbjct: 129 RKKYMGVEVKGKTLGIIGLGRIGSRVAVRAQAFGMKVIANDPYLPPEKAAKINVPLLGFK 188
Query: 696 GXFGPLTDXITLHTPVIEXT 755
+D ITLHTP+ + T
Sbjct: 189 EVL-KKSDYITLHTPLTDET 207
>UniRef50_A2U4T1 Cluster: D-3-phosphoglycerate dehydrogenase; n=14;
Bacillales|Rep: D-3-phosphoglycerate dehydrogenase -
Bacillus coagulans 36D1
Length = 541
Score = 96.7 bits (230), Expect = 7e-19
Identities = 48/119 (40%), Positives = 77/119 (64%), Gaps = 1/119 (0%)
Frame = +1
Query: 136 SVLIVDGVGAKCAELLNAY-GIATTTKAKISKEELLMEIPNHDALVVRSATQVTKEVLDA 312
++L+ D V + + L A+ + I+ E+L I +D L+VR+ T+VTK++++A
Sbjct: 3 NILVTDKVSEEGLKKLYAHKDFIVEHQPGIAPEDLKATIGQYDGLIVRNQTKVTKDIIEA 62
Query: 313 GVKLKVVGRAGAGVDNIDVXSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVQLH 489
L+V+ RAG GVDNIDV +A +KG+ V+N+PG N +SA E T +ML L+R++ Q H
Sbjct: 63 SGNLRVIARAGVGVDNIDVDAATRKGIIVVNSPGGNTISATEHTLAMMLSLSRNIPQAH 121
Score = 42.7 bits (96), Expect = 0.012
Identities = 28/84 (33%), Positives = 39/84 (46%), Gaps = 1/84 (1%)
Frame = +3
Query: 516 RALYTGSELAGXXLXILGLGRVGXXVATXMYAFXMNIIGFQPFRVC*SVRPVPLHXXGAG 695
R + G EL L I+G G++G VA AF M ++G+ P+ R L A
Sbjct: 131 REKFKGVELFKKTLGIIGTGKIGTEVAKRAKAFGMAVLGYDPYLT--EERAAKLGIKKAT 188
Query: 696 -GXFGPLTDXITLHTPVIEXTXXL 764
D ITLHTP+++ T L
Sbjct: 189 LDEIAAQADFITLHTPLMKETKHL 212
>UniRef50_A0L7J1 Cluster: D-3-phosphoglycerate dehydrogenase; n=3;
Proteobacteria|Rep: D-3-phosphoglycerate dehydrogenase -
Magnetococcus sp. (strain MC-1)
Length = 527
Score = 96.7 bits (230), Expect = 7e-19
Identities = 46/113 (40%), Positives = 69/113 (61%)
Frame = +1
Query: 139 VLIVDGVGAKCAELLNAYGIATTTKAKISKEELLMEIPNHDALVVRSATQVTKEVLDAGV 318
VLI D + E+ A G+ K +S +ELL I +D + +RSAT++ + + A
Sbjct: 4 VLIADKMSPMAEEVFRARGLEVDVKVGMSPDELLACIDQYDGIAIRSATRLPAQAIAAAS 63
Query: 319 KLKVVGRAGAGVDNIDVXSAGKKGVGVINAPGANALSACELTCTLMLVLARHV 477
+LKV+GRAG GVDN+D +A +KG+ V+N P NA++ EL TL + ARH+
Sbjct: 64 RLKVIGRAGIGVDNVDTPAASQKGIIVMNTPFGNAITTAELGVTLAMAAARHI 116
Score = 45.2 bits (102), Expect = 0.002
Identities = 32/111 (28%), Positives = 50/111 (45%), Gaps = 2/111 (1%)
Frame = +3
Query: 438 ADLHVDVGSGSPRG-PASLR*XLAGGX-RALYTGSELAGXXLXILGLGRVGXXVATXMYA 611
A+L V + + R PA+ AG ++ + G ELAG ++GLG VG VA +
Sbjct: 102 AELGVTLAMAAARHIPAATASTKAGKWEKSRFMGRELAGKTAGVIGLGNVGRLVAQRLAG 161
Query: 612 FXMNIIGFQPFRVC*SVRPVPLHXXGAGGXFGPLTDXITLHTPVIEXTXXL 764
M ++ + PF + L P D +T+HTP+ + T L
Sbjct: 162 LDMKVVAYDPFINKDRAISLGLEMVDKLEDLWPRVDLLTVHTPLNDHTRNL 212
>UniRef50_A1IDH6 Cluster: D-3-phosphoglycerate dehydrogenase; n=3;
Deltaproteobacteria|Rep: D-3-phosphoglycerate
dehydrogenase - Candidatus Desulfococcus oleovorans Hxd3
Length = 532
Score = 95.5 bits (227), Expect = 2e-18
Identities = 50/117 (42%), Positives = 72/117 (61%), Gaps = 2/117 (1%)
Frame = +1
Query: 139 VLIVDGVGAK-CAELLNAYGIATTTKAKISKEELLMEIPNHDALVVRSATQVTKEVLDAG 315
VL+ D + A + L N G A K + EEL I +DAL++RSAT+VT ++L+AG
Sbjct: 5 VLVSDTIDASGVSRLENESGFAVDVKTGLPPEELKSIIGQYDALIIRSATKVTADILEAG 64
Query: 316 V-KLKVVGRAGAGVDNIDVXSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVQ 483
KLK V RAG G+DN+D+ +A K GV V+N P N ++ E T +M+ L R++ Q
Sbjct: 65 APKLKAVARAGIGLDNVDIPAATKHGVAVMNTPEGNVVTTAEHTIAMMMALTRNIPQ 121
Score = 34.7 bits (76), Expect = 3.1
Identities = 26/98 (26%), Positives = 39/98 (39%)
Frame = +3
Query: 471 PRGPASLR*XLAGGXRALYTGSELAGXXLXILGLGRVGXXVATXMYAFXMNIIGFQPFRV 650
P+G SLR + G E+ L ++G G++G VA MN+I F P
Sbjct: 120 PQGTLSLR--SGQWEKKKLQGREVFNKTLGVIGFGKIGSIVADRARQLKMNVIVFDPNIA 177
Query: 651 C*SVRPVPLHXXGAGGXFGPLTDXITLHTPVIEXTXXL 764
++ F D IT+H P ++ T L
Sbjct: 178 RTTIENEGFEYVSLDDLFA-RADYITVHVPKLKQTVGL 214
>UniRef50_Q97ZK1 Cluster: D-3-phosphoglycerate dehydrogenase; n=4;
Sulfolobaceae|Rep: D-3-phosphoglycerate dehydrogenase -
Sulfolobus solfataricus
Length = 326
Score = 94.3 bits (224), Expect = 4e-18
Identities = 50/116 (43%), Positives = 70/116 (60%)
Frame = +1
Query: 124 VDIKSVLIVDGVGAKCAELLNAYGIATTTKAKISKEELLMEIPNHDALVVRSATQVTKEV 303
+D K VLI D V L G+ K +I++EELL I + L+VRS T+V KE+
Sbjct: 16 LDFK-VLITDPVDQYMIRTLQNNGLIVDYKPEITREELLKIIDQYQVLIVRSRTKVDKEI 74
Query: 304 LDAGVKLKVVGRAGAGVDNIDVXSAGKKGVGVINAPGANALSACELTCTLMLVLAR 471
+ GV LK++ RAG G+DNID A K+ + ++ APGA+ SA ELT L++ AR
Sbjct: 75 IRYGVNLKIIARAGIGLDNIDTEEASKRNIKIVYAPGASTDSAAELTIGLLIAAAR 130
Score = 37.5 bits (83), Expect = 0.43
Identities = 24/79 (30%), Positives = 33/79 (41%)
Frame = +3
Query: 507 GGXRALYTGSELAGXXLXILGLGRVGXXVATXMYAFXMNIIGFQPFRVC*SVRPVPLHXX 686
GG G ELAG + I+G GR+G VA A MN+I + + V +
Sbjct: 141 GGIFKKIEGIELAGKTIGIVGFGRIGTKVAKVCKALDMNVIAYDVINIKEKANIVGVRVA 200
Query: 687 GAGGXFGPLTDXITLHTPV 743
+ +D IT H V
Sbjct: 201 ESLEELLKNSDVITFHVTV 219
>UniRef50_A1SM51 Cluster: D-3-phosphoglycerate dehydrogenase; n=15;
Actinobacteria (class)|Rep: D-3-phosphoglycerate
dehydrogenase - Nocardioides sp. (strain BAA-499 /
JS614)
Length = 536
Score = 93.9 bits (223), Expect = 5e-18
Identities = 46/88 (52%), Positives = 60/88 (68%)
Frame = +1
Query: 232 ELLMEIPNHDALVVRSATQVTKEVLDAGVKLKVVGRAGAGVDNIDVXSAGKKGVGVINAP 411
ELL +P DA++VRSAT+V E L A +LKV+ RAG G+DN+DV +A + GV V+NAP
Sbjct: 44 ELLAALPEADAILVRSATKVDAEALAAARRLKVIARAGVGLDNVDVRAATQAGVMVVNAP 103
Query: 412 GANALSACELTCTLMLVLARHVVQLHCA 495
+N +SA EL LML ARH+ H A
Sbjct: 104 TSNIVSAAELAVALMLAAARHISPAHAA 131
Score = 45.2 bits (102), Expect = 0.002
Identities = 20/43 (46%), Positives = 28/43 (65%)
Frame = +3
Query: 516 RALYTGSELAGXXLXILGLGRVGXXVATXMYAFXMNIIGFQPF 644
RA YTG+EL + I+GLGR+G VA + AF M I+ + P+
Sbjct: 139 RARYTGTELYEKTVGIVGLGRIGVLVAQRLSAFGMKIVAYDPY 181
>UniRef50_Q1AXS3 Cluster: D-3-phosphoglycerate dehydrogenase; n=1;
Rubrobacter xylanophilus DSM 9941|Rep:
D-3-phosphoglycerate dehydrogenase - Rubrobacter
xylanophilus (strain DSM 9941 / NBRC 16129)
Length = 527
Score = 93.5 bits (222), Expect = 6e-18
Identities = 50/113 (44%), Positives = 71/113 (62%)
Frame = +1
Query: 139 VLIVDGVGAKCAELLNAYGIATTTKAKISKEELLMEIPNHDALVVRSATQVTKEVLDAGV 318
VL+ + + + ELL +S ELL I +D L+VRSAT+VT EV++A
Sbjct: 3 VLVTEKLAERGVELLRRE-FEVDVLLGLSPGELLERIGEYDGLIVRSATKVTAEVIEAAG 61
Query: 319 KLKVVGRAGAGVDNIDVXSAGKKGVGVINAPGANALSACELTCTLMLVLARHV 477
+LK +GRAG GVDNID+ +A K+G+ V NAP +N ++A E T LML +AR +
Sbjct: 62 RLKAIGRAGIGVDNIDIEAATKRGILVANAPESNTVAAAEHTLGLMLAVARRI 114
>UniRef50_Q8ZTC7 Cluster: D-3-phosphoglycerate dehydrogenase; n=5;
Thermoproteaceae|Rep: D-3-phosphoglycerate dehydrogenase
- Pyrobaculum aerophilum
Length = 307
Score = 92.3 bits (219), Expect = 1e-17
Identities = 47/118 (39%), Positives = 70/118 (59%)
Frame = +1
Query: 136 SVLIVDGVGAKCAELLNAYGIATTTKAKISKEELLMEIPNHDALVVRSATQVTKEVLDAG 315
S LIVD V E L GI ISK++L+ I N++ L+ R ++ K+++DAG
Sbjct: 2 SALIVDKVDETLKERLERIGIKVDLAPGISKDDLIKIIKNYNILIFRGRLKIDKDIMDAG 61
Query: 316 VKLKVVGRAGAGVDNIDVXSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVQLH 489
LK++ R G G+DN+DV A KKG+ V++AP A + S ELT L+ +AR + L+
Sbjct: 62 QNLKILARYGVGLDNVDVEYAVKKGIAVVSAPNAPSQSVAELTIGLLFSVARRIPLLN 119
Score = 36.7 bits (81), Expect = 0.76
Identities = 27/86 (31%), Positives = 38/86 (44%), Gaps = 6/86 (6%)
Frame = +3
Query: 525 YTGSELAGXXLXILGLGRVGXXVATXMYAFXMNIIGFQPFRVC*SVRPVPLHXXGAGGXF 704
Y G E+AG + I+G GR+G VA + MNI+ V V + GG
Sbjct: 132 YIGIEIAGKTMGIVGFGRIGRFVAQMAKSLGMNILASDVIDVSKEVAKI-------GGRQ 184
Query: 705 GPL------TDXITLHTPVIEXTXXL 764
PL +D +T+H P+ T L
Sbjct: 185 VPLEELLRQSDVVTIHVPLTPETYHL 210
>UniRef50_Q4L766 Cluster: D-3-phosphoglycerate dehydrogenase; n=3;
Staphylococcus|Rep: D-3-phosphoglycerate dehydrogenase -
Staphylococcus haemolyticus (strain JCSC1435)
Length = 532
Score = 91.5 bits (217), Expect = 3e-17
Identities = 46/121 (38%), Positives = 75/121 (61%), Gaps = 1/121 (0%)
Frame = +1
Query: 136 SVLIVDGVGAKCAE-LLNAYGIATTTKAKISKEELLMEIPNHDALVVRSATQVTKEVLDA 312
++L+ D + + LLN K + ++ LL I +++ L+VRS TQVT++V++
Sbjct: 4 NILVSDPISTDGLQSLLNHSDFNVDIKTDLDEQSLLDIIGDYEGLIVRSQTQVTQQVIEK 63
Query: 313 GVKLKVVGRAGAGVDNIDVXSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVQLHC 492
LKV+ RAG GVDNID+ +A +G+ VINAP N +SA E + ++L +AR++ Q H
Sbjct: 64 ASNLKVIARAGVGVDNIDIDAATLQGILVINAPDGNTISATEHSVAMILAMARNIPQAHA 123
Query: 493 A 495
+
Sbjct: 124 S 124
>UniRef50_A4MA79 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase, NAD-binding; n=1; Petrotoga mobilis
SJ95|Rep: D-isomer specific 2-hydroxyacid dehydrogenase,
NAD-binding - Petrotoga mobilis SJ95
Length = 310
Score = 90.6 bits (215), Expect = 4e-17
Identities = 44/92 (47%), Positives = 62/92 (67%)
Frame = +1
Query: 208 TKAKISKEELLMEIPNHDALVVRSATQVTKEVLDAGVKLKVVGRAGAGVDNIDVXSAGKK 387
T + K+ L +I D L+VRSAT+VTKE+L+ KLK+V RAG G+DNIDV +A K
Sbjct: 27 TSEHLEKDVLKDKIKEIDVLIVRSATKVTKEILEHADKLKIVARAGMGLDNIDVDTAKLK 86
Query: 388 GVGVINAPGANALSACELTCTLMLVLARHVVQ 483
G+ V+N PG N+LS EL ++L + RH+ +
Sbjct: 87 GITVLNTPGQNSLSVAELVIGMVLDIYRHITR 118
>UniRef50_UPI00015BAF48 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase, NAD-binding; n=1; Ignicoccus hospitalis
KIN4/I|Rep: D-isomer specific 2-hydroxyacid
dehydrogenase, NAD-binding - Ignicoccus hospitalis
KIN4/I
Length = 308
Score = 90.2 bits (214), Expect = 6e-17
Identities = 50/111 (45%), Positives = 69/111 (62%), Gaps = 1/111 (0%)
Frame = +1
Query: 142 LIVDGVGAKCAELLNAYGIATTTKAKISKEELLME-IPNHDALVVRSATQVTKEVLDAGV 318
L+ D V ELL GI + K E+L E I D L+VRS T+V +EV++A
Sbjct: 5 LVTDKVHPAGLELLREKGIEVVEDLEAYKPEVLKERIKGFDVLIVRSRTKVRREVIEAAD 64
Query: 319 KLKVVGRAGAGVDNIDVXSAGKKGVGVINAPGANALSACELTCTLMLVLAR 471
KLKV+ RAG+G+DNID+ +A +KG+ V+NAP A + EL +M+VLAR
Sbjct: 65 KLKVIARAGSGLDNIDLEAAKEKGIKVVNAPDALKNAVAELVIGMMVVLAR 115
Score = 39.9 bits (89), Expect = 0.081
Identities = 22/75 (29%), Positives = 36/75 (48%)
Frame = +3
Query: 531 GSELAGXXLXILGLGRVGXXVATXMYAFXMNIIGFQPFRVC*SVRPVPLHXXGAGGXFGP 710
G ELAG L ++G GR+G VA A MN+I + + + + + +
Sbjct: 134 GFELAGKTLGVVGFGRIGREVAKKAKALGMNVIAYDVVDLSETAKEMGVEFTQDLEELLR 193
Query: 711 LTDXITLHTPVIEXT 755
+D ++LH P+ E T
Sbjct: 194 KSDVVSLHVPLTEQT 208
>UniRef50_Q1PZY1 Cluster: Similar to D-3-phosphoglycerate
dehydrogenase; n=1; Candidatus Kuenenia
stuttgartiensis|Rep: Similar to D-3-phosphoglycerate
dehydrogenase - Candidatus Kuenenia stuttgartiensis
Length = 535
Score = 89.0 bits (211), Expect = 1e-16
Identities = 51/119 (42%), Positives = 67/119 (56%)
Frame = +1
Query: 139 VLIVDGVGAKCAELLNAYGIATTTKAKISKEELLMEIPNHDALVVRSATQVTKEVLDAGV 318
VLI D + C E+L G+ K + EL I D ++VRS T++T VL+
Sbjct: 12 VLIADDLPDVCNEILQNAGVEVLKKTGLKPPELDAVIKMCDGVIVRSNTKLTAPVLEKSE 71
Query: 319 KLKVVGRAGAGVDNIDVXSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVQLHCA 495
KLK + RAG GVDNIDV +A KKG+ V+N P N +S E T L+ L+R V Q CA
Sbjct: 72 KLKAICRAGVGVDNIDVPAATKKGIVVMNTPAGNIISTAEHTIALLCSLSRFVPQA-CA 129
Score = 44.0 bits (99), Expect = 0.005
Identities = 26/80 (32%), Positives = 35/80 (43%)
Frame = +3
Query: 525 YTGSELAGXXLXILGLGRVGXXVATXMYAFXMNIIGFQPFRVC*SVRPVPLHXXGAGGXF 704
+TG +L G I+GLGRVG VA A M +IG+ PF +H
Sbjct: 141 FTGQQLTGKTFGIIGLGRVGRQVAKRAAALEMKVIGYDPFITTEISSQYNIHIVKNLRDL 200
Query: 705 GPLTDXITLHTPVIEXTXXL 764
D IT+H + + T L
Sbjct: 201 LAQADYITIHVTLNKETKNL 220
>UniRef50_O04130 Cluster: D-3-phosphoglycerate dehydrogenase,
chloroplast precursor; n=13; Magnoliophyta|Rep:
D-3-phosphoglycerate dehydrogenase, chloroplast
precursor - Arabidopsis thaliana (Mouse-ear cress)
Length = 624
Score = 88.2 bits (209), Expect = 2e-16
Identities = 47/116 (40%), Positives = 73/116 (62%), Gaps = 1/116 (0%)
Frame = +1
Query: 139 VLIVDGVGAKCAELLNAYGIATTTKAKISKEELLMEIPNHDALVVRSATQVTKEVLDAGV 318
+L+ + +G LL +G + +S E+L ++ DAL+VRS T+VT+EV +A
Sbjct: 85 ILVTEKLGEAGVNLLREFGDVDCSY-DLSPEDLKKKVAESDALIVRSGTKVTREVFEAAK 143
Query: 319 -KLKVVGRAGAGVDNIDVXSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVQ 483
+LKVVGRAG G+DN+D+ +A + G V+NAP AN ++A E L+ +AR+V Q
Sbjct: 144 GRLKVVGRAGVGIDNVDLQAATEHGCLVVNAPTANTVAAAEHGIALLASMARNVAQ 199
Score = 37.5 bits (83), Expect = 0.43
Identities = 21/84 (25%), Positives = 34/84 (40%)
Frame = +3
Query: 516 RALYTGSELAGXXLXILGLGRVGXXVATXMYAFXMNIIGFQPFRVC*SVRPVPLHXXGAG 695
R+ Y G L G L ++G G+VG VA M +I P+ R + +
Sbjct: 211 RSKYVGVSLVGKTLAVMGFGKVGTEVARRAKGLGMTVISHDPYAPADRARALGVDLVSFD 270
Query: 696 GXFGPLTDXITLHTPVIEXTXXLY 767
D ++LH P+ T ++
Sbjct: 271 QAIS-TADFVSLHMPLTPATKKVF 293
>UniRef50_Q1IVI0 Cluster: D-3-phosphoglycerate dehydrogenase; n=2;
Acidobacteria|Rep: D-3-phosphoglycerate dehydrogenase -
Acidobacteria bacterium (strain Ellin345)
Length = 531
Score = 87.8 bits (208), Expect = 3e-16
Identities = 42/84 (50%), Positives = 60/84 (71%)
Frame = +1
Query: 226 KEELLMEIPNHDALVVRSATQVTKEVLDAGVKLKVVGRAGAGVDNIDVXSAGKKGVGVIN 405
KE+LL ++ DAL+VRSA V +L+ +L+V+GRAG GVDNI++ +A +KG+ V+N
Sbjct: 34 KEQLLEQLKGADALIVRSAVFVDAAMLEHADQLRVIGRAGVGVDNIELEAATRKGIAVMN 93
Query: 406 APGANALSACELTCTLMLVLARHV 477
PGANA++ E T LML LAR +
Sbjct: 94 TPGANAIAVAEHTIGLMLALARFI 117
Score = 37.5 bits (83), Expect = 0.43
Identities = 16/38 (42%), Positives = 23/38 (60%)
Frame = +3
Query: 531 GSELAGXXLXILGLGRVGXXVATXMYAFXMNIIGFQPF 644
G+EL G L I+GLGR+G VA +F M ++ P+
Sbjct: 136 GTELRGKTLGIVGLGRIGLEVARRAASFGMTLVAHDPY 173
>UniRef50_A7P9P5 Cluster: Chromosome chr3 scaffold_8, whole genome
shotgun sequence; n=1; Vitis vinifera|Rep: Chromosome
chr3 scaffold_8, whole genome shotgun sequence - Vitis
vinifera (Grape)
Length = 653
Score = 87.8 bits (208), Expect = 3e-16
Identities = 49/117 (41%), Positives = 74/117 (63%), Gaps = 1/117 (0%)
Frame = +1
Query: 136 SVLIVDGVGAKCAELLNAYGIATTTKAKISKEELLMEIPNHDALVVRSATQVTKEVLDAG 315
+VL+ + +GA +LL + +S EEL +I DAL+VRS T+V++EV +A
Sbjct: 113 TVLVAEKLGAAGLDLLKDFANVDCAY-NLSPEELCTKISLCDALIVRSGTKVSREVFEAS 171
Query: 316 V-KLKVVGRAGAGVDNIDVXSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVQ 483
+LKVVGRAG G+DN+D+ +A + G V+NAP AN ++A E L+ +AR+V Q
Sbjct: 172 SGRLKVVGRAGVGIDNVDLAAATEHGCLVVNAPTANTVAAAEHGIALLTAMARNVAQ 228
Score = 39.1 bits (87), Expect = 0.14
Identities = 22/80 (27%), Positives = 32/80 (40%)
Frame = +3
Query: 516 RALYTGSELAGXXLXILGLGRVGXXVATXMYAFXMNIIGFQPFRVC*SVRPVPLHXXGAG 695
R Y G L G L ++G G+VG V M++I P+ R + + G
Sbjct: 240 RNKYVGVSLVGKTLAVMGFGKVGSEVTRRAKGLGMHVIAHDPYAAADRARAIGVELVGFD 299
Query: 696 GXFGPLTDXITLHTPVIEXT 755
D I+LH P+ T
Sbjct: 300 EAIS-TADFISLHMPLTPAT 318
>UniRef50_Q9RUU0 Cluster: D-3-phosphoglycerate dehydrogenase; n=4;
Deinococci|Rep: D-3-phosphoglycerate dehydrogenase -
Deinococcus radiodurans
Length = 544
Score = 87.4 bits (207), Expect = 4e-16
Identities = 43/98 (43%), Positives = 65/98 (66%), Gaps = 1/98 (1%)
Frame = +1
Query: 181 LNAYGIATTTKAKISKEELLMEIPNHDALVVRSATQVTKEVLDA-GVKLKVVGRAGAGVD 357
L+ G + + +EE L +P++DAL+ RS T+V +E+LDA G +LKV+GR G GVD
Sbjct: 33 LDHEGFQIDYQGNLEREETLRRLPDYDALITRSRTKVDRELLDAAGPRLKVIGRGGVGVD 92
Query: 358 NIDVXSAGKKGVGVINAPGANALSACELTCTLMLVLAR 471
NID+ A ++G+ V+NAP +N +SA EL ++ AR
Sbjct: 93 NIDLEYASRRGLLVLNAPESNNVSAAELAVMHLMAAAR 130
Score = 40.7 bits (91), Expect = 0.046
Identities = 23/84 (27%), Positives = 37/84 (44%)
Frame = +3
Query: 504 AGGXRALYTGSELAGXXLXILGLGRVGXXVATXMYAFXMNIIGFQPFRVC*SVRPVPLHX 683
AG + G EL L I+GLGR+G VA MN++ + P+ + +
Sbjct: 141 AGEWDRKFLGLELTDKTLGIVGLGRIGSIVADRAQGLHMNVVAYDPYVPENKFERLGVQR 200
Query: 684 XGAGGXFGPLTDXITLHTPVIEXT 755
+ D +T+HTP+ + T
Sbjct: 201 AASLDELLGQVDALTVHTPLTDET 224
>UniRef50_Q0J5C2 Cluster: Os08g0447000 protein; n=11;
Viridiplantae|Rep: Os08g0447000 protein - Oryza sativa
subsp. japonica (Rice)
Length = 666
Score = 87.4 bits (207), Expect = 4e-16
Identities = 45/93 (48%), Positives = 65/93 (69%), Gaps = 1/93 (1%)
Frame = +1
Query: 220 ISKEELLMEIPNHDALVVRSATQVTKEVLDAGV-KLKVVGRAGAGVDNIDVXSAGKKGVG 396
+S ELL ++ DAL+VRS T+VT+EVL+AG +L+VVGRAG G+DN+D+ +A + G
Sbjct: 106 MSPAELLAKVAQFDALIVRSGTKVTREVLEAGRGRLRVVGRAGVGIDNVDLQAATEAGCL 165
Query: 397 VINAPGANALSACELTCTLMLVLARHVVQLHCA 495
V+NAP AN ++A E L+ +AR+V Q A
Sbjct: 166 VVNAPTANTVAAAEHGIALLASMARNVSQADAA 198
Score = 40.3 bits (90), Expect = 0.061
Identities = 23/84 (27%), Positives = 34/84 (40%)
Frame = +3
Query: 516 RALYTGSELAGXXLXILGLGRVGXXVATXMYAFXMNIIGFQPFRVC*SVRPVPLHXXGAG 695
R Y G L G L ++G G+VG VA M++I P+ R +
Sbjct: 218 RTKYVGVSLVGKTLAVMGFGKVGSEVARRAKGLGMHVIAHDPYAPADRARAIGAELVSFD 277
Query: 696 GXFGPLTDXITLHTPVIEXTXXLY 767
G D I+LH P+ T ++
Sbjct: 278 EAIG-RADFISLHMPLTPATSKVF 300
>UniRef50_A1DFM4 Cluster: D-3-phosphoglycerate dehydrogenase; n=10;
Fungi/Metazoa group|Rep: D-3-phosphoglycerate
dehydrogenase - Neosartorya fischeri (strain ATCC 1020 /
DSM 3700 / NRRL 181)(Aspergillus fischerianus (strain
ATCC 1020 / DSM 3700 / NRRL 181))
Length = 582
Score = 87.0 bits (206), Expect = 5e-16
Identities = 47/113 (41%), Positives = 69/113 (61%)
Frame = +1
Query: 139 VLIVDGVGAKCAELLNAYGIATTTKAKISKEELLMEIPNHDALVVRSATQVTKEVLDAGV 318
VL+ + + LL A + + + +ELL IP ++ALVVRS T+VT +L A
Sbjct: 11 VLVPEKLSPDGLALLRA-SLEVDERRGLDADELLQIIPEYEALVVRSETKVTGNLLRAAK 69
Query: 319 KLKVVGRAGAGVDNIDVXSAGKKGVGVINAPGANALSACELTCTLMLVLARHV 477
+LKVV RAG GVDN+DV A K G+ V+N+P N +A E T L++ +AR++
Sbjct: 70 QLKVVARAGVGVDNVDVEEATKLGIVVVNSPSGNIGAAAEHTIALLIAMARNI 122
Score = 43.6 bits (98), Expect = 0.007
Identities = 24/80 (30%), Positives = 36/80 (45%)
Frame = +3
Query: 516 RALYTGSELAGXXLXILGLGRVGXXVATXMYAFXMNIIGFQPFRVC*SVRPVPLHXXGAG 695
R+ + G E+ G L I+GLG+VG VA MN+ P+ + +
Sbjct: 136 RSKFVGVEVKGKTLSIIGLGKVGLTVARLAKGLGMNVNALDPYASPAVAVSASVTLVSSL 195
Query: 696 GXFGPLTDXITLHTPVIEXT 755
P D +T+HTP+I T
Sbjct: 196 SELLPTADFLTIHTPLIAST 215
>UniRef50_Q8EN61 Cluster: Phosphoglycerate dehydrogenase; n=2;
Bacillaceae|Rep: Phosphoglycerate dehydrogenase -
Oceanobacillus iheyensis
Length = 528
Score = 86.2 bits (204), Expect = 9e-16
Identities = 47/120 (39%), Positives = 74/120 (61%), Gaps = 1/120 (0%)
Frame = +1
Query: 139 VLIVDGVGAKCAE-LLNAYGIATTTKAKISKEELLMEIPNHDALVVRSATQVTKEVLDAG 315
VLI D + + + L A I +++EL +I + DA++VRS TQVT+ +++
Sbjct: 5 VLISDPLSEEGLKPLQEAENIEVVINPGWNEQELSDQIDSFDAILVRSQTQVTRALIEKA 64
Query: 316 VKLKVVGRAGAGVDNIDVXSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVQLHCA 495
LK++GRAG GVDNID+ +A + GV V+NAP N SA E T +++ L+R++ Q + A
Sbjct: 65 SNLKIIGRAGVGVDNIDLEAATENGVIVVNAPNGNTNSAAEHTMAMIMALSRNIPQAYHA 124
Score = 41.5 bits (93), Expect = 0.027
Identities = 27/83 (32%), Positives = 38/83 (45%)
Frame = +3
Query: 516 RALYTGSELAGXXLXILGLGRVGXXVATXMYAFXMNIIGFQPFRVC*SVRPVPLHXXGAG 695
R + G EL L I+GLGR+G VA MN+I + PF + + G
Sbjct: 132 RKRFVGVELKQKTLGIVGLGRIGAEVAARAKGQRMNVIAYDPFFTEEKAEQMGVQ-YGTL 190
Query: 696 GXFGPLTDXITLHTPVIEXTXXL 764
D IT+HTP+++ T L
Sbjct: 191 EDVLRAGDFITVHTPLLKETKHL 213
>UniRef50_Q8YIU3 Cluster: D-3-PHOSPHOGLYCERATE DEHYDROGENASE; n=75;
Bacteria|Rep: D-3-PHOSPHOGLYCERATE DEHYDROGENASE -
Brucella melitensis
Length = 538
Score = 85.0 bits (201), Expect = 2e-15
Identities = 43/115 (37%), Positives = 69/115 (60%), Gaps = 2/115 (1%)
Frame = +1
Query: 139 VLIVDGVGAKCAELLNAYGIATTTKAKISK--EELLMEIPNHDALVVRSATQVTKEVLDA 312
VL+ D + ++ G+ + K E+LL I +D L +RSAT+VT++++ A
Sbjct: 10 VLVSDKLSPTAVQIFKDRGVDVDYLPDLGKDKEKLLEVIGEYDGLAIRSATKVTEKLIAA 69
Query: 313 GVKLKVVGRAGAGVDNIDVXSAGKKGVGVINAPGANALSACELTCTLMLVLARHV 477
KLKVVGRAG GVDN+D+ +A ++G+ V+N P N+++ E LM +AR +
Sbjct: 70 AKKLKVVGRAGIGVDNVDIPAASRRGIIVMNTPFGNSITTAEHAIALMFAVARQL 124
Score = 42.3 bits (95), Expect = 0.015
Identities = 23/77 (29%), Positives = 36/77 (46%)
Frame = +3
Query: 525 YTGSELAGXXLXILGLGRVGXXVATXMYAFXMNIIGFQPFRVC*SVRPVPLHXXGAGGXF 704
+ G E+ G L ++G G +G VAT M+++ F PF + + +
Sbjct: 141 FMGVEITGKTLGVVGCGNIGSIVATRGIGLKMHVVAFDPFLSDARAQELGVEKVELDELL 200
Query: 705 GPLTDXITLHTPVIEXT 755
D ITLHTP+I+ T
Sbjct: 201 A-RADFITLHTPLIDKT 216
>UniRef50_Q2LGV1 Cluster: Phosphoglycerate dehydrogenase; n=6;
Halobacteriaceae|Rep: Phosphoglycerate dehydrogenase -
Haloquadratum walsbyi
Length = 536
Score = 84.6 bits (200), Expect = 3e-15
Identities = 50/117 (42%), Positives = 64/117 (54%)
Frame = +1
Query: 139 VLIVDGVGAKCAELLNAYGIATTTKAKISKEELLMEIPNHDALVVRSATQVTKEVLDAGV 318
VL+ D + E L A G + T I E LL I + +ALVVRS T V + V +A
Sbjct: 7 VLVTDPIDDAGLERLRAAGHSVETAYDIGDEALLNTITDVNALVVRSGTDVNEAVFEAAS 66
Query: 319 KLKVVGRAGAGVDNIDVXSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVQLH 489
L +VGRAG GVDNID+ +A + GV V NAP N +A E T + AR + Q H
Sbjct: 67 DLIIVGRAGIGVDNIDIDAATEHGVIVANAPEGNVRAAAEHTVAMTFAGARSIPQAH 123
Score = 39.1 bits (87), Expect = 0.14
Identities = 15/40 (37%), Positives = 26/40 (65%)
Frame = +3
Query: 525 YTGSELAGXXLXILGLGRVGXXVATXMYAFXMNIIGFQPF 644
Y G+E+ G L ++GLGRVG VA + + M+++ + P+
Sbjct: 136 YLGTEVNGKTLGVVGLGRVGQEVAKRLESLGMDLVAYDPY 175
>UniRef50_Q8TYK0 Cluster: Predicted dehydrogenase related to
phosphoglycerate dehydrogenase; n=9; Archaea|Rep:
Predicted dehydrogenase related to phosphoglycerate
dehydrogenase - Methanopyrus kandleri
Length = 522
Score = 84.2 bits (199), Expect = 4e-15
Identities = 44/115 (38%), Positives = 69/115 (60%)
Frame = +1
Query: 139 VLIVDGVGAKCAELLNAYGIATTTKAKISKEELLMEIPNHDALVVRSATQVTKEVLDAGV 318
+L+ D + L G + +EE+ + + DA VVRS T+VT+E+++
Sbjct: 4 ILVTDPIHEDALRKLEELGEVVVLE-DADEEEIREHVRDADAWVVRSGTRVTRELIEEAK 62
Query: 319 KLKVVGRAGAGVDNIDVXSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVQ 483
LKV+ RAG GVDNIDV +A ++G+ V+NAP ++++S E T L+L LAR + Q
Sbjct: 63 NLKVIARAGVGVDNIDVKAATERGIIVVNAPESSSISVAEHTMGLILALARKIPQ 117
Score = 41.5 bits (93), Expect = 0.027
Identities = 23/80 (28%), Positives = 36/80 (45%)
Frame = +3
Query: 516 RALYTGSELAGXXLXILGLGRVGXXVATXMYAFXMNIIGFQPFRVC*SVRPVPLHXXGAG 695
R + G ELAG L ++GLGR+G VA AF M + + P+ + +
Sbjct: 129 RKRFMGVELAGKTLGLIGLGRIGQQVAKRAKAFEMEVTAYDPYIPEKVAEELGVELVDEL 188
Query: 696 GXFGPLTDXITLHTPVIEXT 755
D +++H P+ E T
Sbjct: 189 EELLERADVVSIHVPLTEET 208
>UniRef50_Q97N23 Cluster: D-3-phosphoglycerate dehydrogenase; n=10;
Clostridiaceae|Rep: D-3-phosphoglycerate dehydrogenase -
Clostridium acetobutylicum
Length = 305
Score = 83.8 bits (198), Expect = 5e-15
Identities = 46/88 (52%), Positives = 59/88 (67%), Gaps = 4/88 (4%)
Frame = +1
Query: 226 KEELLMEIPNHDALVVRSATQVTKEVLDA----GVKLKVVGRAGAGVDNIDVXSAGKKGV 393
K+ELL++I D LVVRSAT+VTKEV+DA G KLK++ RAG GVDNIDV A KG+
Sbjct: 32 KDELLVKIKEFDVLVVRSATKVTKEVIDAATVKGAKLKLIIRAGVGVDNIDVTYARDKGL 91
Query: 394 GVINAPGANALSACELTCTLMLVLARHV 477
V N P A++ S EL M ++R +
Sbjct: 92 TVNNTPNASSASVAELAIGHMFAVSRFI 119
>UniRef50_A7CYD6 Cluster: D-3-phosphoglycerate dehydrogenase; n=1;
Opitutaceae bacterium TAV2|Rep: D-3-phosphoglycerate
dehydrogenase - Opitutaceae bacterium TAV2
Length = 529
Score = 83.8 bits (198), Expect = 5e-15
Identities = 47/116 (40%), Positives = 69/116 (59%), Gaps = 1/116 (0%)
Frame = +1
Query: 139 VLIVDGVGAK-CAELLNAYGIATTTKAKISKEELLMEIPNHDALVVRSATQVTKEVLDAG 315
+L+ D + K A L G S E++L + + A+ VRS T++T+EV+ A
Sbjct: 3 ILVADKISPKGVAYLRQQEGFEVVEAYGSSPEKVLELVKDVHAIAVRSETKITREVIAAA 62
Query: 316 VKLKVVGRAGAGVDNIDVXSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVQ 483
+LKVVGRAG GVDN+DV +A ++GV V+N P N ++ ELT T +L +R V Q
Sbjct: 63 PQLKVVGRAGVGVDNVDVEAATERGVVVMNTPAGNTIATAELTFTHILCGSRPVSQ 118
Score = 42.7 bits (96), Expect = 0.012
Identities = 25/98 (25%), Positives = 45/98 (45%)
Frame = +3
Query: 516 RALYTGSELAGXXLXILGLGRVGXXVATXMYAFXMNIIGFQPFRVC*SVRPVPLHXXGAG 695
R ++G EL L ++G+GR+G VA AF M ++ + P+ + + +
Sbjct: 130 RKSFSGVELFKKTLGVIGMGRIGGEVARRAVAFGMKVLAYDPYLAPSRAKAMQVEVATLD 189
Query: 696 GXFGPLTDXITLHTPVIEXTXXLYPXPMS*XQCXKGVK 809
D IT+H P+ + T + + +C KGV+
Sbjct: 190 EILAQ-ADYITVHMPLTDDTKYMI-DEAALAKCKKGVR 225
>UniRef50_O33116 Cluster: D-3-phosphoglycerate dehydrogenase; n=28;
Actinomycetales|Rep: D-3-phosphoglycerate dehydrogenase
- Mycobacterium leprae
Length = 528
Score = 83.8 bits (198), Expect = 5e-15
Identities = 42/86 (48%), Positives = 57/86 (66%)
Frame = +1
Query: 226 KEELLMEIPNHDALVVRSATQVTKEVLDAGVKLKVVGRAGAGVDNIDVXSAGKKGVGVIN 405
+ +LL +P DAL+VRSAT V EVL A KLK+V RAG G+DN+DV +A +GV V+N
Sbjct: 34 RTKLLAAVPEADALLVRSATTVDAEVLAAAPKLKIVARAGVGLDNVDVDAATARGVLVVN 93
Query: 406 APGANALSACELTCTLMLVLARHVVQ 483
AP +N SA E L+L +R + +
Sbjct: 94 APTSNIHSAAEHALALLLAASRQIAE 119
Score = 40.7 bits (91), Expect = 0.046
Identities = 15/43 (34%), Positives = 29/43 (67%)
Frame = +3
Query: 516 RALYTGSELAGXXLXILGLGRVGXXVATXMYAFXMNIIGFQPF 644
R+ ++G+E+ G + ++GLGR+G VA + AF ++I + P+
Sbjct: 131 RSSFSGTEIFGKTVGVVGLGRIGQLVAARIAAFGAHVIAYDPY 173
>UniRef50_P35136 Cluster: D-3-phosphoglycerate dehydrogenase; n=8;
Bacillaceae|Rep: D-3-phosphoglycerate dehydrogenase -
Bacillus subtilis
Length = 525
Score = 83.8 bits (198), Expect = 5e-15
Identities = 41/80 (51%), Positives = 54/80 (67%)
Frame = +1
Query: 244 EIPNHDALVVRSATQVTKEVLDAGVKLKVVGRAGAGVDNIDVXSAGKKGVGVINAPGANA 423
E+ DAL+VRSAT+VT+++ + LK+VGRAG GVDNID+ A K GV VINAP N
Sbjct: 37 ELHTFDALLVRSATKVTEDLFNKMTSLKIVGRAGVGVDNIDIDEATKHGVIVINAPNGNT 96
Query: 424 LSACELTCTLMLVLARHVVQ 483
+S E T ++ L RH+ Q
Sbjct: 97 ISTAEHTFAMISSLMRHIPQ 116
Score = 48.0 bits (109), Expect = 3e-04
Identities = 29/83 (34%), Positives = 40/83 (48%)
Frame = +3
Query: 516 RALYTGSELAGXXLXILGLGRVGXXVATXMYAFXMNIIGFQPFRVC*SVRPVPLHXXGAG 695
R Y GSEL G L I+GLGR+G +A AF M + F PF + + ++
Sbjct: 128 RTAYVGSELYGKTLGIVGLGRIGSEIAQRRGAFGMTVHVFDPFLTEERAKKIGVNSRTFE 187
Query: 696 GXFGPLTDXITLHTPVIEXTXXL 764
D IT+HTP+ + T L
Sbjct: 188 EVL-ESADIITVHTPLTKETKGL 209
>UniRef50_UPI0000DA2A77 Cluster: PREDICTED: similar to
D-3-phosphoglycerate dehydrogenase (3-PGDH); n=2; Rattus
norvegicus|Rep: PREDICTED: similar to
D-3-phosphoglycerate dehydrogenase (3-PGDH) - Rattus
norvegicus
Length = 155
Score = 82.6 bits (195), Expect = 1e-14
Identities = 44/114 (38%), Positives = 71/114 (62%)
Frame = +1
Query: 127 DIKSVLIVDGVGAKCAELLNAYGIATTTKAKISKEELLMEIPNHDALVVRSATQVTKEVL 306
+I VLI D + C ++L G+ ++KEEL+ E+ + + L ++SAT+VT + +
Sbjct: 5 NICKVLISDSLDPCCQKILQDGGLQN-----LNKEELITELQDCEGLTIQSATKVTADAV 59
Query: 307 DAGVKLKVVGRAGAGVDNIDVXSAGKKGVGVINAPGANALSACELTCTLMLVLA 468
+A KL+VVG AG G+DN+D+ +A +K + V+N N+LS ELTC + L A
Sbjct: 60 NAAQKLQVVGSAGTGMDNVDLEAAMRKSILVMNTSNGNSLSPVELTCGMNLCQA 113
>UniRef50_UPI0000DC0E13 Cluster: 3-phosphoglycerate dehydrogenase;
n=4; Amniota|Rep: 3-phosphoglycerate dehydrogenase -
Rattus norvegicus
Length = 316
Score = 82.2 bits (194), Expect = 2e-14
Identities = 44/117 (37%), Positives = 71/117 (60%)
Frame = +1
Query: 127 DIKSVLIVDGVGAKCAELLNAYGIATTTKAKISKEELLMEIPNHDALVVRSATQVTKEVL 306
++ VLI D + C +LL G+ K +SKEEL++EI + + T+VT +V
Sbjct: 5 NLHKVLISDILDPGCWKLLKDGGLQVVEKQNLSKEELIVEIQDCET------TKVTADVT 58
Query: 307 DAGVKLKVVGRAGAGVDNIDVXSAGKKGVGVINAPGANALSACELTCTLMLVLARHV 477
+ KL++VGRAG G+DN+++ +A K + V+N P +LSA ELTC +++ L R +
Sbjct: 59 NTAEKLQLVGRAGTGMDNVNLEAAMTKSILVMNTPNGKSLSASELTCGMIVCLTRQI 115
Score = 52.4 bits (120), Expect = 1e-05
Identities = 34/95 (35%), Positives = 46/95 (48%)
Frame = +3
Query: 525 YTGSELAGXXLXILGLGRVGXXVATXMYAFXMNIIGFQPFRVC*SVRPVPLHXXGAGGXF 704
+ G+EL G L ILGLGR+G V T M AF M +GF P + +
Sbjct: 125 FMGTELNGKTLGILGLGRIGREVTTQMQAFRMKAVGFDPISSPEIAASFGVQQLLLEELW 184
Query: 705 GPLTDXITLHTPVIEXTXXLYPXPMS*XQCXKGVK 809
PL D IT+HTP++ T L + C KG++
Sbjct: 185 -PLCDFITVHTPLLLSTTGLL-NDSTFAWCKKGMR 217
>UniRef50_Q6L245 Cluster: D-3-phosphoglycerate dehydrogenase; n=2;
Thermoplasmatales|Rep: D-3-phosphoglycerate
dehydrogenase - Picrophilus torridus
Length = 299
Score = 81.8 bits (193), Expect = 2e-14
Identities = 39/115 (33%), Positives = 70/115 (60%)
Frame = +1
Query: 139 VLIVDGVGAKCAELLNAYGIATTTKAKISKEELLMEIPNHDALVVRSATQVTKEVLDAGV 318
+LI D V E L+ I+++ELL +I ++D ++VRS T++ ++++D
Sbjct: 5 ILICDPVDGIMIEKLSK-DFDIDNSPDITRDELLKKIGDYDIIIVRSRTKIDRDIIDNAK 63
Query: 319 KLKVVGRAGAGVDNIDVXSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVQ 483
+LK++ RAG G D+IDV A +KG+ ++ APG++ S ELT ++ AR +++
Sbjct: 64 RLKIIARAGIGTDSIDVDYAQEKGIKIVYAPGSSTESVVELTVAFAVIAARQIIK 118
>UniRef50_A6C9V4 Cluster: Phosphoglycerate dehydrogenase; n=1;
Planctomyces maris DSM 8797|Rep: Phosphoglycerate
dehydrogenase - Planctomyces maris DSM 8797
Length = 541
Score = 81.4 bits (192), Expect = 3e-14
Identities = 43/114 (37%), Positives = 68/114 (59%), Gaps = 1/114 (0%)
Frame = +1
Query: 139 VLIVDGVGAKCAELLNAYG-IATTTKAKISKEELLMEIPNHDALVVRSATQVTKEVLDAG 315
VLI D + ++L I ++ +S EE+ + + D +++RSAT++T+EVL
Sbjct: 4 VLITDNLSPAGLKILEDNPEIEVDIRSGLSPEEVREALKSADGIIIRSATKLTEEVLKGQ 63
Query: 316 VKLKVVGRAGAGVDNIDVXSAGKKGVGVINAPGANALSACELTCTLMLVLARHV 477
+LK + RAG GVDNID +A ++G+ V+N P N S E T LM+ LAR++
Sbjct: 64 PRLKAIVRAGVGVDNIDRAAATREGIVVMNTPAGNTTSTAEQTIALMMALARNI 117
Score = 48.0 bits (109), Expect = 3e-04
Identities = 26/83 (31%), Positives = 38/83 (45%)
Frame = +3
Query: 516 RALYTGSELAGXXLXILGLGRVGXXVATXMYAFXMNIIGFQPFRVC*SVRPVPLHXXGAG 695
R TG+++AG L I+GLGR+G VA M +IG+ PF +
Sbjct: 131 RKKLTGTQVAGKTLAIIGLGRIGLSVAHRAQGLEMKVIGYDPFMSAERAAEYGIELYKEV 190
Query: 696 GXFGPLTDXITLHTPVIEXTXXL 764
D +T+HTP+ + T L
Sbjct: 191 DELVKHCDFLTVHTPLTDETRDL 213
>UniRef50_Q7UQL2 Cluster: Phosphoglycerate dehydrogenase; n=2;
Planctomycetaceae|Rep: Phosphoglycerate dehydrogenase -
Rhodopirellula baltica
Length = 540
Score = 80.6 bits (190), Expect = 5e-14
Identities = 38/114 (33%), Positives = 66/114 (57%), Gaps = 1/114 (0%)
Frame = +1
Query: 139 VLIVDGVGAKCAELLNAY-GIATTTKAKISKEELLMEIPNHDALVVRSATQVTKEVLDAG 315
+L++D + + +LL A GI + K+ EEL + DA ++RS +T E L+
Sbjct: 4 ILVLDDIAQEGIDLLEASEGIEYEVRTKLKGEELRQSLNEFDAAILRSGVTITPESLEGN 63
Query: 316 VKLKVVGRAGAGVDNIDVXSAGKKGVGVINAPGANALSACELTCTLMLVLARHV 477
+L+ + RAG G DNID +A ++G+ V+N P N +S E T ++L ++R++
Sbjct: 64 TRLRALVRAGVGTDNIDKPAATRRGIVVMNTPAGNTVSTAEHTFAMLLAMSRNI 117
Score = 54.0 bits (124), Expect = 5e-06
Identities = 26/83 (31%), Positives = 42/83 (50%)
Frame = +3
Query: 516 RALYTGSELAGXXLXILGLGRVGXXVATXMYAFXMNIIGFQPFRVC*SVRPVPLHXXGAG 695
R + G+++AG L I+G+GR+G VA+ AF M+++ F PF + +
Sbjct: 131 RKKFMGTQVAGKTLGIVGMGRIGREVASRAQAFDMDVVAFDPFLTDDQAESLKVRRVATV 190
Query: 696 GXFGPLTDXITLHTPVIEXTXXL 764
P D +T+HTP+ T L
Sbjct: 191 DDMLPQIDYLTVHTPLTPETRGL 213
>UniRef50_A6C2G1 Cluster: Phosphoglycerate dehydrogenase; n=1;
Planctomyces maris DSM 8797|Rep: Phosphoglycerate
dehydrogenase - Planctomyces maris DSM 8797
Length = 316
Score = 80.6 bits (190), Expect = 5e-14
Identities = 43/117 (36%), Positives = 68/117 (58%), Gaps = 1/117 (0%)
Frame = +1
Query: 130 IKSVLIVDGV-GAKCAELLNAYGIATTTKAKISKEELLMEIPNHDALVVRSATQVTKEVL 306
+ VL+ + + G L+ + + + + L +I N AL+VR+ T+V +E++
Sbjct: 1 MSDVLVTENIQGVSMNRLIQEHDVEFDAYLWQNIDLLKQKIQNTRALIVRNQTKVDRELI 60
Query: 307 DAGVKLKVVGRAGAGVDNIDVXSAGKKGVGVINAPGANALSACELTCTLMLVLARHV 477
DA +LK++ RAGAG+DN+D A +KG+ V P AN+LS ELT LML L R +
Sbjct: 61 DAAPELKIIARAGAGLDNVDTEYAHEKGIVVCFTPDANSLSVAELTIGLMLALMRKI 117
Score = 47.2 bits (107), Expect = 5e-04
Identities = 24/56 (42%), Positives = 32/56 (57%), Gaps = 1/56 (1%)
Frame = +3
Query: 480 PASLR*XLAGGXRAL-YTGSELAGXXLXILGLGRVGXXVATXMYAFXMNIIGFQPF 644
P + + L GG L +TG+EL G ++GLGR+G AT AF MNI+ PF
Sbjct: 118 PEARQDTLTGGWNRLKFTGTELYGKSFGLIGLGRIGSFTATRAKAFGMNILAADPF 173
>UniRef50_A4FIF2 Cluster: D-3-phosphoglycerate dehydrogenase; n=1;
Saccharopolyspora erythraea NRRL 2338|Rep:
D-3-phosphoglycerate dehydrogenase - Saccharopolyspora
erythraea (strain NRRL 23338)
Length = 316
Score = 80.6 bits (190), Expect = 5e-14
Identities = 45/111 (40%), Positives = 68/111 (61%), Gaps = 4/111 (3%)
Frame = +1
Query: 175 ELLNAYGIATT----TKAKISKEELLMEIPNHDALVVRSATQVTKEVLDAGVKLKVVGRA 342
E+L A G A T+A + ++LL +P DAL+V VT EV++AG +L+V+ +
Sbjct: 20 EILEAAGSAAVRPHETRA-MPADDLLARVPEADALIV-GMDLVTAEVIEAGPRLRVIAKH 77
Query: 343 GAGVDNIDVXSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVQLHCA 495
G GVDNID+ +A +G+ V+ APG+N+ + ELT LM+ AR + H A
Sbjct: 78 GVGVDNIDLDAARARGIPVVFAPGSNSRAVAELTFGLMIAAARRIAAAHTA 128
Score = 45.2 bits (102), Expect = 0.002
Identities = 21/48 (43%), Positives = 29/48 (60%)
Frame = +3
Query: 501 LAGGXRALYTGSELAGXXLXILGLGRVGXXVATXMYAFXMNIIGFQPF 644
+AG LY G ELAG L ++G GR+G +A AF M ++G+ PF
Sbjct: 130 VAGDWPKLY-GPELAGRTLGVIGFGRIGRLLAGYAQAFGMTVVGYDPF 176
>UniRef50_Q0EUV6 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase, NAD-binding; n=4; Thermoanaerobacter
ethanolicus|Rep: D-isomer specific 2-hydroxyacid
dehydrogenase, NAD-binding - Thermoanaerobacter
ethanolicus X514
Length = 320
Score = 80.2 bits (189), Expect = 6e-14
Identities = 41/87 (47%), Positives = 61/87 (70%)
Frame = +1
Query: 220 ISKEELLMEIPNHDALVVRSATQVTKEVLDAGVKLKVVGRAGAGVDNIDVXSAGKKGVGV 399
+S EEL+ + + DAL+V + +VT++V++AG KLKV+ R G G DN+D+ +A KKG+ V
Sbjct: 40 LSAEELIPLVKDADALIVGN-DKVTEDVINAGKKLKVISRYGVGYDNVDLNAAKKKGIVV 98
Query: 400 INAPGANALSACELTCTLMLVLARHVV 480
N P AN S +L LMLVLAR+++
Sbjct: 99 TNTPNANNNSVADLVIGLMLVLARNLL 125
Score = 35.5 bits (78), Expect = 1.7
Identities = 16/47 (34%), Positives = 28/47 (59%)
Frame = +3
Query: 504 AGGXRALYTGSELAGXXLXILGLGRVGXXVATXMYAFXMNIIGFQPF 644
+GG + + G+E+ G L I+GLG++G VA F MN++ + +
Sbjct: 133 SGGWKRIM-GTEIYGKTLGIIGLGKIGKGVAKRAKGFDMNVLCYDVY 178
>UniRef50_A0RW58 Cluster: Phosphoglycerate dehydrogenase; n=3;
Crenarchaeota|Rep: Phosphoglycerate dehydrogenase -
Cenarchaeum symbiosum
Length = 310
Score = 79.8 bits (188), Expect = 8e-14
Identities = 40/115 (34%), Positives = 63/115 (54%)
Frame = +1
Query: 133 KSVLIVDGVGAKCAELLNAYGIATTTKAKISKEELLMEIPNHDALVVRSATQVTKEVLDA 312
++VLI D +L G+ + K +I+ EEL E P + ++VRS T +T E++ +
Sbjct: 5 ETVLICDKADPVLGRILQQNGLRVSYKPEITPEELAAEAPGYSIIIVRSRTTITGEIIRS 64
Query: 313 GVKLKVVGRAGAGVDNIDVXSAGKKGVGVINAPGANALSACELTCTLMLVLARHV 477
K++ R G G+DNID+ +A GV VINA + EL +ML +AR +
Sbjct: 65 AKDCKIIARVGVGLDNIDLAAAESAGVRVINAVEGATTAVSELVLGMMLCMARQI 119
Score = 36.7 bits (81), Expect = 0.76
Identities = 24/76 (31%), Positives = 35/76 (46%), Gaps = 1/76 (1%)
Frame = +3
Query: 531 GSELAGXXLXILGLGRVGXXVATXMYAFXMNIIGFQPFRV-C*SVRPVPLHXXGAGGXFG 707
G+EL G L I+GLG +G + MNIIG + R V L G
Sbjct: 138 GTELKGKYLGIVGLGNIGRRLGRLARGMNMNIIGHDVVPIDAEFSREVGLMKTDLNTLLG 197
Query: 708 PLTDXITLHTPVIEXT 755
+D ++LH P+++ T
Sbjct: 198 S-SDYVSLHVPLLDST 212
>UniRef50_Q81T55 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase family protein; n=41; cellular
organisms|Rep: D-isomer specific 2-hydroxyacid
dehydrogenase family protein - Bacillus anthracis
Length = 323
Score = 79.4 bits (187), Expect = 1e-13
Identities = 43/102 (42%), Positives = 60/102 (58%), Gaps = 1/102 (0%)
Frame = +1
Query: 175 ELLNAYGIATTTKAK-ISKEELLMEIPNHDALVVRSATQVTKEVLDAGVKLKVVGRAGAG 351
ELL + + K + IS +EL + + DAL+ +T+VTKEV+DA LK+V GAG
Sbjct: 16 ELLKDHDVEMYDKEELISLDELTERVKDKDALLSLLSTKVTKEVIDAAPSLKIVANYGAG 75
Query: 352 VDNIDVXSAGKKGVGVINAPGANALSACELTCTLMLVLARHV 477
DNID AG+KG+ V N P + + ELT L+L AR +
Sbjct: 76 YDNIDYTYAGEKGIAVTNTPKVSTEATAELTFALLLAAARRI 117
Score = 34.7 bits (76), Expect = 3.1
Identities = 17/41 (41%), Positives = 23/41 (56%)
Frame = +3
Query: 525 YTGSELAGXXLXILGLGRVGXXVATXMYAFXMNIIGFQPFR 647
+ G E+ G + I+GLG +G VA AF MNI+ P R
Sbjct: 137 FLGREVHGKTIGIIGLGEIGKAVAKRAKAFGMNILYTGPNR 177
>UniRef50_Q1K3M3 Cluster: D-3-phosphoglycerate dehydrogenase; n=1;
Desulfuromonas acetoxidans DSM 684|Rep:
D-3-phosphoglycerate dehydrogenase - Desulfuromonas
acetoxidans DSM 684
Length = 528
Score = 77.8 bits (183), Expect = 3e-13
Identities = 44/118 (37%), Positives = 68/118 (57%), Gaps = 1/118 (0%)
Frame = +1
Query: 139 VLIVDGVGAKCAELLN-AYGIATTTKAKISKEELLMEIPNHDALVVRSATQVTKEVLDAG 315
VLI D + +L + A GI + I+ + LL I N+DAL+VR T V++E++ A
Sbjct: 3 VLISDNFSSAGLKLFDEAEGITADYQPGITHDNLLKIINNYDALIVRGGTTVSEELIFAA 62
Query: 316 VKLKVVGRAGAGVDNIDVXSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVQLH 489
+LK++ RAG GV+NI + +A KG+ V N P + + E +M+ LAR + Q H
Sbjct: 63 KRLKIIARAGIGVENIAMDAANIKGIVVTNTPLGSTTTIAEHAIAMMMSLARLIPQAH 120
>UniRef50_A2A023 Cluster: D-3-phosphoglycerate dehydrogenase; n=2;
Flexibacteraceae|Rep: D-3-phosphoglycerate dehydrogenase
- Microscilla marina ATCC 23134
Length = 316
Score = 77.8 bits (183), Expect = 3e-13
Identities = 38/114 (33%), Positives = 68/114 (59%)
Frame = +1
Query: 136 SVLIVDGVGAKCAELLNAYGIATTTKAKISKEELLMEIPNHDALVVRSATQVTKEVLDAG 315
++LI+D + LL + GI + I++ E+L + ++ L+VRS T + ++++
Sbjct: 4 NILIIDKMHPSITSLLESRGIQGDYRPDITRAEILTIVDKYEGLMVRSKTAIDEDLIGRA 63
Query: 316 VKLKVVGRAGAGVDNIDVXSAGKKGVGVINAPGANALSACELTCTLMLVLARHV 477
+LKV+ RAGAG+D ID+ +A +G+ V+NAP N + E T ++L L +V
Sbjct: 64 SRLKVIARAGAGLDKIDLSAANARGIKVLNAPEGNRDAVGEQTIGMLLSLLHNV 117
>UniRef50_Q11UL6 Cluster: Phosphoglycerate dehydrogenase; n=1;
Cytophaga hutchinsonii ATCC 33406|Rep: Phosphoglycerate
dehydrogenase - Cytophaga hutchinsonii (strain ATCC
33406 / NCIMB 9469)
Length = 314
Score = 77.0 bits (181), Expect = 6e-13
Identities = 42/114 (36%), Positives = 66/114 (57%)
Frame = +1
Query: 142 LIVDGVGAKCAELLNAYGIATTTKAKISKEELLMEIPNHDALVVRSATQVTKEVLDAGVK 321
LIVD V +LL+ IA K SKE + +P ++ LV+RS +V K+++D+ K
Sbjct: 7 LIVDDVDTALFQLLDKAAIAYDYKPDWSKETCIEALPAYEGLVIRSKFRVDKKIIDSCTK 66
Query: 322 LKVVGRAGAGVDNIDVXSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVQ 483
L+ + RAGAGVDNID +K + + +A N ++ E T L+L L ++V+
Sbjct: 67 LQFIARAGAGVDNIDKEYLKEKNIALFHASEGNRVAVGEHTLGLILALINNIVR 120
>UniRef50_Q0ETU3 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase, NAD-binding; n=1; Thermoanaerobacter
ethanolicus X514|Rep: D-isomer specific 2-hydroxyacid
dehydrogenase, NAD-binding - Thermoanaerobacter
ethanolicus X514
Length = 324
Score = 76.6 bits (180), Expect = 8e-13
Identities = 39/116 (33%), Positives = 70/116 (60%)
Frame = +1
Query: 130 IKSVLIVDGVGAKCAELLNAYGIATTTKAKISKEELLMEIPNHDALVVRSATQVTKEVLD 309
+K VL+ + + + +LL T S++ L+ + + DA+++R+ +++T+EV++
Sbjct: 1 MKKVLLSEEIHPEGRKLLEGK-FEIVTAPDTSQQTLISMVKDVDAIILRTRSKITREVIE 59
Query: 310 AGVKLKVVGRAGAGVDNIDVXSAGKKGVGVINAPGANALSACELTCTLMLVLARHV 477
LK++ R GAGVDNIDV +A +KG+ V N P N LS E T ++L L++ +
Sbjct: 60 NAPHLKIISRTGAGVDNIDVNAATEKGILVCNLPAVNNLSVAEHTIAMILNLSKQL 115
>UniRef50_Q5KN70 Cluster: D-3-phosphoglycerate dehydrogenase 2,
putative; n=2; Filobasidiella neoformans|Rep:
D-3-phosphoglycerate dehydrogenase 2, putative -
Cryptococcus neoformans (Filobasidiella neoformans)
Length = 508
Score = 76.6 bits (180), Expect = 8e-13
Identities = 36/116 (31%), Positives = 72/116 (62%), Gaps = 2/116 (1%)
Frame = +1
Query: 139 VLIVDGVGAKCAELLNAYG--IATTTKAKISKEELLMEIPNHDALVVRSATQVTKEVLDA 312
+L+++ + A+ L + G + TKA ++EEL+ ++PN+ A+ +RS T++T +V+DA
Sbjct: 101 ILLLENINLDAADYLKSQGYEVDHVTKA-YTEEELIAKLPNYHAIGIRSKTKITAKVIDA 159
Query: 313 GVKLKVVGRAGAGVDNIDVXSAGKKGVGVINAPGANALSACELTCTLMLVLARHVV 480
+L +G G + +D+ A K+G+ V N+P +N+ S EL + ++ L+R ++
Sbjct: 160 NPQLLAIGCFCIGTNQVDLEHAAKRGIAVFNSPFSNSRSVAELVISEIIALSRQII 215
>UniRef50_A4ARG6 Cluster: D-3-phosphoglycerate dehydrogenase; n=14;
Bacteroidetes|Rep: D-3-phosphoglycerate dehydrogenase -
Flavobacteriales bacterium HTCC2170
Length = 329
Score = 75.8 bits (178), Expect = 1e-12
Identities = 48/109 (44%), Positives = 66/109 (60%), Gaps = 3/109 (2%)
Frame = +1
Query: 124 VDIKSVLIVDGVGAKCAELLNAYG--IATTTKAKISKEELLMEIPNHDA-LVVRSATQVT 294
V+ +L DG+ L A G I+TTT A+ +E + E N A L+VRSATQV
Sbjct: 11 VNSMKILANDGISQTGINELEAAGFEISTTTVAQEQLKEFINE--NQIAGLLVRSATQVR 68
Query: 295 KEVLDAGVKLKVVGRAGAGVDNIDVXSAGKKGVGVINAPGANALSACEL 441
K+++D LK++GR G G+DNIDV A +KG+ VIN P A++ S EL
Sbjct: 69 KDIIDNCPSLKLIGRGGVGMDNIDVAYAKEKGLHVINTPAASSESVAEL 117
Score = 33.5 bits (73), Expect = 7.1
Identities = 15/38 (39%), Positives = 19/38 (50%)
Frame = +3
Query: 531 GSELAGXXLXILGLGRVGXXVATXMYAFXMNIIGFQPF 644
GSEL G L ++G GR+G A M +I PF
Sbjct: 154 GSELRGKTLGVIGFGRIGQATAKIALGIGMKVIYSDPF 191
>UniRef50_A5N5A9 Cluster: SerA; n=1; Clostridium kluyveri DSM
555|Rep: SerA - Clostridium kluyveri DSM 555
Length = 320
Score = 74.5 bits (175), Expect = 3e-12
Identities = 37/111 (33%), Positives = 66/111 (59%)
Frame = +1
Query: 139 VLIVDGVGAKCAELLNAYGIATTTKAKISKEELLMEIPNHDALVVRSATQVTKEVLDAGV 318
+LI + + + E L +G S++ L+ E+ + DA++VR A +T++V+ AG
Sbjct: 5 ILITESIEEEGVEYLKKFGYEIKMPRDTSEDVLIEEVKDCDAILVRMAN-ITEKVIRAGK 63
Query: 319 KLKVVGRAGAGVDNIDVXSAGKKGVGVINAPGANALSACELTCTLMLVLAR 471
KLKV+ R G GV+N+D+ +A + + + NAP +N + E T L++ LA+
Sbjct: 64 KLKVISRFGVGVNNVDIKTASELSIQITNAPESNKNTVAEYTMGLIIALAK 114
>UniRef50_A6Q7Q2 Cluster: D-3-phosphoglycerate dehydrogenase; n=27;
Epsilonproteobacteria|Rep: D-3-phosphoglycerate
dehydrogenase - Sulfurovum sp. (strain NBC37-1)
Length = 529
Score = 73.3 bits (172), Expect = 7e-12
Identities = 41/121 (33%), Positives = 65/121 (53%), Gaps = 2/121 (1%)
Frame = +1
Query: 133 KSVLIVDGVGAKCAELL-NAYGIATTTKAKISKEELLMEI-PNHDALVVRSATQVTKEVL 306
K++++ D + ++L N I A K++L+ EI P D + RS+T V L
Sbjct: 4 KTIVVCDHIHQSGLDILANDSEIKLINAADEPKDKLIAEIIPLADVAITRSSTDVDAAFL 63
Query: 307 DAGVKLKVVGRAGAGVDNIDVXSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVQL 486
++ K+ + RAG GVDN+D+ + K+G+ V+N P AN ++A ELT ML R
Sbjct: 64 ESAKKITAIVRAGVGVDNVDIPGSSKQGIVVMNVPTANTIAAVELTLAHMLSCVRQFPYA 123
Query: 487 H 489
H
Sbjct: 124 H 124
Score = 34.7 bits (76), Expect = 3.1
Identities = 23/77 (29%), Positives = 35/77 (45%), Gaps = 2/77 (2%)
Frame = +3
Query: 531 GSELAGXXLXILGLGRVGXXVATXMYAFXMNIIGFQPFRVC*SVRPVPLHXXGAGGXFGP 710
G+EL L I+G G +G V AF M+++ + P+ + + G F
Sbjct: 140 GTELKDKKLGIIGFGNIGSRVGKRAKAFEMDVLAYDPYIDPSKATDLDI---GYTKNFED 196
Query: 711 L--TDXITLHTPVIEXT 755
+ D IT+HTP E T
Sbjct: 197 ILACDIITIHTPKTEET 213
>UniRef50_Q0RXU8 Cluster: Phosphoglycerate dehydrogenase; n=1;
Rhodococcus sp. RHA1|Rep: Phosphoglycerate dehydrogenase
- Rhodococcus sp. (strain RHA1)
Length = 325
Score = 72.9 bits (171), Expect = 9e-12
Identities = 45/119 (37%), Positives = 65/119 (54%)
Frame = +1
Query: 130 IKSVLIVDGVGAKCAELLNAYGIATTTKAKISKEELLMEIPNHDALVVRSATQVTKEVLD 309
I +V+ D G +L + I A +E+LL ALVVR+ TQV +++++
Sbjct: 8 IDAVITEDVWGRAFNDLGTSRSILRAPHAWQDREKLLELGSRSRALVVRNRTQVDRQLIE 67
Query: 310 AGVKLKVVGRAGAGVDNIDVXSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVQL 486
A L+V+ RAG G+DNIDV A + GV V+ GANA+S E T + L R V+L
Sbjct: 68 ACPSLRVIARAGVGLDNIDVKCANEAGVVVVAPLGANAISVAEHTIGMALAAVRRTVEL 126
>UniRef50_A6EBH4 Cluster: Phosphoglycerate dehydrogenase; n=1;
Pedobacter sp. BAL39|Rep: Phosphoglycerate dehydrogenase
- Pedobacter sp. BAL39
Length = 309
Score = 72.9 bits (171), Expect = 9e-12
Identities = 40/109 (36%), Positives = 62/109 (56%)
Frame = +1
Query: 139 VLIVDGVGAKCAELLNAYGIATTTKAKISKEELLMEIPNHDALVVRSATQVTKEVLDAGV 318
+LIVD + A E A G + ++ + L I ++D + VR+ ++ +E++DAG
Sbjct: 6 ILIVDELHAIFKERAAAMGYEVHDEPNFTRAQTLAAIADYDGIAVRTKFRIDRELIDAGT 65
Query: 319 KLKVVGRAGAGVDNIDVXSAGKKGVGVINAPGANALSACELTCTLMLVL 465
KLK + RAGAG+DNID A ++ + +INAP N + E LML L
Sbjct: 66 KLKFIARAGAGLDNIDEAVALERNIHLINAPEGNMDAVGEHAVGLMLSL 114
>UniRef50_A6CKS4 Cluster: Putative uncharacterized protein; n=1;
Bacillus sp. SG-1|Rep: Putative uncharacterized protein
- Bacillus sp. SG-1
Length = 322
Score = 72.5 bits (170), Expect = 1e-11
Identities = 40/119 (33%), Positives = 69/119 (57%)
Frame = +1
Query: 139 VLIVDGVGAKCAELLNAYGIATTTKAKISKEELLMEIPNHDALVVRSATQVTKEVLDAGV 318
VLI + + +LL G ++E L+ + + DA+++R+A ++++ V++
Sbjct: 5 VLIPQPIAKEGIDLLEKEGAEVIIPPDYNEETLISHVSDVDAILIRTA-KLSRVVIEKAS 63
Query: 319 KLKVVGRAGAGVDNIDVXSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVQLHCA 495
KLKV+ R G GVDNID+ +A +G+ V NAP AN + E TL+L +R ++Q+ A
Sbjct: 64 KLKVIARHGIGVDNIDLEAASDRGILVTNAPFANVNAVAEHVLTLILSGSRQLIQVDSA 122
>UniRef50_Q8XPB1 Cluster: D-3-phosphoglycerate dehydrogenase; n=3;
Clostridium perfringens|Rep: D-3-phosphoglycerate
dehydrogenase - Clostridium perfringens
Length = 301
Score = 71.7 bits (168), Expect = 2e-11
Identities = 43/118 (36%), Positives = 64/118 (54%), Gaps = 3/118 (2%)
Frame = +1
Query: 139 VLIVDGVGAKCAELLNAYGIATTTKAKISKEELLMEIPNHDALVVRSATQVTKEVLDAGV 318
+L+ DG+ K L G T E+L +I D +V+RSAT++ +E++D +
Sbjct: 4 ILLNDGLDKKAISNLEFLGFDVDTN-HYDIEDLKEKIKKVDCIVIRSATKIRRELIDEAI 62
Query: 319 K---LKVVGRAGAGVDNIDVXSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVQ 483
K LK++ R G GVDNIDV A + G+ V N P A++ S E+ M LAR + Q
Sbjct: 63 KGGKLKLIIRGGVGVDNIDVQYAEQNGIKVRNTPNASSSSVAEIILAHMFSLARFLNQ 120
Score = 35.1 bits (77), Expect = 2.3
Identities = 17/37 (45%), Positives = 21/37 (56%)
Frame = +3
Query: 525 YTGSELAGXXLXILGLGRVGXXVATXMYAFXMNIIGF 635
Y G EL G L I+G+GR+G +A A M II F
Sbjct: 135 YVGVELEGKTLGIIGMGRIGSELAKKCTALGMKIIYF 171
>UniRef50_A4FHH0 Cluster: D-3-phosphoglycerate dehydrogenase; n=1;
Saccharopolyspora erythraea NRRL 2338|Rep:
D-3-phosphoglycerate dehydrogenase - Saccharopolyspora
erythraea (strain NRRL 23338)
Length = 336
Score = 71.7 bits (168), Expect = 2e-11
Identities = 43/113 (38%), Positives = 61/113 (53%)
Frame = +1
Query: 139 VLIVDGVGAKCAELLNAYGIATTTKAKISKEELLMEIPNHDALVVRSATQVTKEVLDAGV 318
VL+ D A+ L +G + + E+L + + LVVRS T V V++A
Sbjct: 3 VLLADAFPAEHVSALTEHGHDCDYQPDTTTEQLPDRLTGREVLVVRS-TAVPSAVIEAAD 61
Query: 319 KLKVVGRAGAGVDNIDVXSAGKKGVGVINAPGANALSACELTCTLMLVLARHV 477
L++V RAG+G + ID SA ++GV V N PG NA++ EL LML L R V
Sbjct: 62 SLRLVIRAGSGTNTIDCESAAERGVHVCNVPGRNAIAVAELAFALMLALDRSV 114
>UniRef50_Q5V1E2 Cluster: D-3-phosphoglycerate dehydrogenase; n=2;
Haloarcula marismortui|Rep: D-3-phosphoglycerate
dehydrogenase - Haloarcula marismortui (Halobacterium
marismortui)
Length = 323
Score = 70.9 bits (166), Expect = 4e-11
Identities = 42/106 (39%), Positives = 55/106 (51%)
Frame = +1
Query: 160 GAKCAELLNAYGIATTTKAKISKEELLMEIPNHDALVVRSATQVTKEVLDAGVKLKVVGR 339
G A +L+A T A E + + DAL+V + TQVT EV++A LKVVGR
Sbjct: 15 GETRAAVLDAVDATVETIAAKEPEAVARAVDGADALIVDAGTQVTAEVIEAADSLKVVGR 74
Query: 340 AGAGVDNIDVXSAGKKGVGVINAPGANALSACELTCTLMLVLARHV 477
AG G+DNI V +A GV V+N P + T LML R +
Sbjct: 75 AGIGMDNIAVRAAVAAGVTVVNVPDYSVEEVSTHTFALMLACLRRI 120
>UniRef50_Q4LAE6 Cluster: Similar to glycerate dehydrogenase; n=1;
Staphylococcus haemolyticus JCSC1435|Rep: Similar to
glycerate dehydrogenase - Staphylococcus haemolyticus
(strain JCSC1435)
Length = 179
Score = 70.5 bits (165), Expect = 5e-11
Identities = 33/91 (36%), Positives = 59/91 (64%)
Frame = +1
Query: 205 TTKAKISKEELLMEIPNHDALVVRSATQVTKEVLDAGVKLKVVGRAGAGVDNIDVXSAGK 384
T + IS+E L+ +I + DAL+ +TQV+++V+++ KLK++ GAG +NID+ +A +
Sbjct: 28 TGETLISQELLIQKIQDADALITLLSTQVSRQVIESAPKLKIIANYGAGFNNIDIQAARE 87
Query: 385 KGVGVINAPGANALSACELTCTLMLVLARHV 477
+ V N P A+ + ELT ++L +AR +
Sbjct: 88 HHINVTNTPIASTNATAELTMGILLAVARRI 118
>UniRef50_Q214B1 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase, NAD-binding precursor; n=2;
Proteobacteria|Rep: D-isomer specific 2-hydroxyacid
dehydrogenase, NAD-binding precursor - Rhodopseudomonas
palustris (strain BisB18)
Length = 336
Score = 69.3 bits (162), Expect = 1e-10
Identities = 39/114 (34%), Positives = 65/114 (57%)
Frame = +1
Query: 133 KSVLIVDGVGAKCAELLNAYGIATTTKAKISKEELLMEIPNHDALVVRSATQVTKEVLDA 312
K +L+ + + E L + G T + + ++ ++ +IP D ++VR + ++ V DA
Sbjct: 23 KRILLPQELMPEGREYLESRGYQLVTGSGMDEDHVIHDIPECDGIIVR-LSPMSARVFDA 81
Query: 313 GVKLKVVGRAGAGVDNIDVXSAGKKGVGVINAPGANALSACELTCTLMLVLARH 474
KLKV+ R G+G D +D+ +A K GV V+NAP AN+ S EL ML +R+
Sbjct: 82 AKKLKVLVRHGSGYDTVDLAAAKKHGVTVLNAPLANSTSVAELALFYMLHCSRN 135
Score = 36.7 bits (81), Expect = 0.76
Identities = 15/38 (39%), Positives = 23/38 (60%)
Frame = +3
Query: 534 SELAGXXLXILGLGRVGXXVATXMYAFXMNIIGFQPFR 647
SE+A L ++G+G +G VA F M +IGF P++
Sbjct: 157 SEIACKKLGLIGVGNIGSRVAKMARGFDMQVIGFDPYK 194
>UniRef50_A7HEG1 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase NAD-binding; n=4; Bacteria|Rep: D-isomer
specific 2-hydroxyacid dehydrogenase NAD-binding -
Anaeromyxobacter sp. Fw109-5
Length = 399
Score = 69.3 bits (162), Expect = 1e-10
Identities = 40/113 (35%), Positives = 61/113 (53%)
Frame = +1
Query: 139 VLIVDGVGAKCAELLNAYGIATTTKAKISKEELLMEIPNHDALVVRSATQVTKEVLDAGV 318
+L+ D + A G+ + ++ +EL + LVVRS QV +V DA
Sbjct: 3 ILVADAFPTERLADFQALGLEVAHRPDVAVQELAAAARDAAILVVRSK-QVQADVFDAAP 61
Query: 319 KLKVVGRAGAGVDNIDVXSAGKKGVGVINAPGANALSACELTCTLMLVLARHV 477
L +V RAGAGV+ IDV +A ++GV V N PG N+++ EL L++ L R +
Sbjct: 62 GLSLVVRAGAGVNTIDVAAASRRGVYVANCPGQNSIAVAELAIGLVVALDRRI 114
>UniRef50_Q88YI0 Cluster: Phosphoglycerate dehydrogenase; n=5;
Bacilli|Rep: Phosphoglycerate dehydrogenase -
Lactobacillus plantarum
Length = 324
Score = 68.5 bits (160), Expect = 2e-10
Identities = 32/88 (36%), Positives = 54/88 (61%)
Frame = +1
Query: 220 ISKEELLMEIPNHDALVVRSATQVTKEVLDAGVKLKVVGRAGAGVDNIDVXSAGKKGVGV 399
IS EL+ + + D L++ +TQV ++VLD LK++ GAG +NID+ +A K+ + V
Sbjct: 34 ISHAELIRRVADADFLIIPLSTQVDQDVLDHAPHLKLIANFGAGTNNIDIAAAAKRQIPV 93
Query: 400 INAPGANALSACELTCTLMLVLARHVVQ 483
N P +A++ E T L++ LA +V+
Sbjct: 94 TNTPNVSAVATAESTVGLIISLAHRIVE 121
Score = 37.5 bits (83), Expect = 0.43
Identities = 26/80 (32%), Positives = 36/80 (45%)
Frame = +3
Query: 525 YTGSELAGXXLXILGLGRVGXXVATXMYAFXMNIIGFQPFRVC*SVRPVPLHXXGAGGXF 704
+ G L G L ILGLG++G VA ++AF M I+ Q R+ S +
Sbjct: 139 FLGHNLQGKTLGILGLGQIGQAVAKRLHAFDMPILYSQHHRLPISRETQLGATFVSQDEL 198
Query: 705 GPLTDXITLHTPVIEXTXXL 764
D +TLH P+ T L
Sbjct: 199 LQRADIVTLHLPLTTQTTHL 218
>UniRef50_A1JTE6 Cluster: Putative oxidoreductase; n=1; Yersinia
enterocolitica subsp. enterocolitica 8081|Rep: Putative
oxidoreductase - Yersinia enterocolitica serotype O:8 /
biotype 1B (strain 8081)
Length = 338
Score = 68.5 bits (160), Expect = 2e-10
Identities = 40/96 (41%), Positives = 58/96 (60%), Gaps = 1/96 (1%)
Frame = +1
Query: 211 KAKISKEELLMEIPNHDA-LVVRSATQVTKEVLDAGVKLKVVGRAGAGVDNIDVXSAGKK 387
K K+S+E+L+ HDA +V S +T V+ A +LK++ A NIDV +A ++
Sbjct: 31 KPKLSEEQLIAL--GHDADFLVTSYDDITARVIKACPQLKLIACTRANPVNIDVNAATER 88
Query: 388 GVGVINAPGANALSACELTCTLMLVLARHVVQLHCA 495
G+ V+ PG N+ +A ELT LML LARH+ Q H A
Sbjct: 89 GIPVVYTPGRNSDAAAELTIALMLNLARHIPQAHSA 124
>UniRef50_Q49ZM5 Cluster: Putative dehydrogenase; n=1;
Staphylococcus saprophyticus subsp. saprophyticus ATCC
15305|Rep: Putative dehydrogenase - Staphylococcus
saprophyticus subsp. saprophyticus (strain ATCC 15305
/DSM 20229)
Length = 318
Score = 68.1 bits (159), Expect = 3e-10
Identities = 34/86 (39%), Positives = 51/86 (59%)
Frame = +1
Query: 220 ISKEELLMEIPNHDALVVRSATQVTKEVLDAGVKLKVVGRAGAGVDNIDVXSAGKKGVGV 399
I KE L + + DAL+ +T V KEV+DA LK++ GAG +N+D+ A ++ + V
Sbjct: 34 IDKETLKQGVKDADALISLLSTSVDKEVIDAANNLKIITNYGAGFNNVDIDYARQQNIDV 93
Query: 400 INAPGANALSACELTCTLMLVLARHV 477
N P A+ S ELT L+L +AR +
Sbjct: 94 TNTPKASTNSTAELTFALVLAVARRI 119
Score = 35.1 bits (77), Expect = 2.3
Identities = 15/35 (42%), Positives = 22/35 (62%)
Frame = +3
Query: 525 YTGSELAGXXLXILGLGRVGXXVATXMYAFXMNII 629
+ G E++G + I+GLG +G VA AF MNI+
Sbjct: 139 FRGREVSGKTIGIIGLGEIGSAVARRAKAFDMNIL 173
>UniRef50_Q8EP33 Cluster: Glycerate dehydrogenase; n=2;
Bacillaceae|Rep: Glycerate dehydrogenase -
Oceanobacillus iheyensis
Length = 314
Score = 67.7 bits (158), Expect = 4e-10
Identities = 39/103 (37%), Positives = 57/103 (55%), Gaps = 2/103 (1%)
Frame = +1
Query: 175 ELLNAYGIATT--TKAKISKEELLMEIPNHDALVVRSATQVTKEVLDAGVKLKVVGRAGA 348
E LN G T T I KE+L + + +++ + Q+ KE++DA LK + + GA
Sbjct: 20 ENLNRLGNVTILDTDNGIEKEKLKQAVREVE-VIITAVVQIDKEIIDAAPNLKYIMKFGA 78
Query: 349 GVDNIDVXSAGKKGVGVINAPGANALSACELTCTLMLVLARHV 477
G DNID A +KG+ V N PG NA + +L LML AR++
Sbjct: 79 GYDNIDFKYAREKGIPVTNTPGQNADAVADLAIGLMLATARNI 121
>UniRef50_Q8EMJ8 Cluster: Hypothetical conserved protein; n=1;
Oceanobacillus iheyensis|Rep: Hypothetical conserved
protein - Oceanobacillus iheyensis
Length = 319
Score = 67.7 bits (158), Expect = 4e-10
Identities = 37/116 (31%), Positives = 61/116 (52%)
Frame = +1
Query: 139 VLIVDGVGAKCAELLNAYGIATTTKAKISKEELLMEIPNHDALVVRSATQVTKEVLDAGV 318
VL+ + + LL G + + L+ + + DA++ R+ +++VL+
Sbjct: 5 VLVPQKIAQEGIRLLEENGASIVVPPSHDEATLVEYVSDVDAIIARTEIY-SEKVLENAN 63
Query: 319 KLKVVGRAGAGVDNIDVXSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVQL 486
+LK++ R G GVDNIDV +A K G+ V N P AN + EL T ML RH++ +
Sbjct: 64 RLKIIARHGIGVDNIDVKAATKYGIKVTNTPSANINAVAELVLTFMLASTRHLLPI 119
Score = 38.7 bits (86), Expect = 0.19
Identities = 24/79 (30%), Positives = 36/79 (45%), Gaps = 1/79 (1%)
Frame = +3
Query: 531 GSELAGXXLXILGLGRVGXXVATXM-YAFXMNIIGFQPFRVC*SVRPVPLHXXGAGGXFG 707
G EL G + I+G G +G +A MNI+ F P+ SV P + +
Sbjct: 136 GYELNGKTVGIIGFGNIGRLIAEKCRLGLGMNIVVFDPYVTAESVEPY-VELTESLEDLL 194
Query: 708 PLTDXITLHTPVIEXTXXL 764
++D +TLH P + T L
Sbjct: 195 RISDVVTLHVPYVRATHHL 213
>UniRef50_A2F8V0 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase, putative; n=3; Trichomonas vaginalis
G3|Rep: D-isomer specific 2-hydroxyacid dehydrogenase,
putative - Trichomonas vaginalis G3
Length = 396
Score = 67.7 bits (158), Expect = 4e-10
Identities = 39/101 (38%), Positives = 55/101 (54%)
Frame = +1
Query: 139 VLIVDGVGAKCAELLNAYGIATTTKAKISKEELLMEIPNHDALVVRSATQVTKEVLDAGV 318
+LI D + K E+L A G I++ L EI +++ L+VRS V ++A
Sbjct: 4 ILIADSLSPKAVEMLKAAGHEVRMDPSITQASLANEISDYNVLIVRSKV-VNAAAIEAAK 62
Query: 319 KLKVVGRAGAGVDNIDVXSAGKKGVGVINAPGANALSACEL 441
L ++ RAGAGV+ IDV +A KGV V N PG N + EL
Sbjct: 63 GLNLIIRAGAGVNTIDVNAASAKGVLVCNTPGMNNDAVAEL 103
>UniRef50_Q46VE6 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase, catalytic region:D- isomer specific
2-hydroxyacid dehydrogenase, NAD-binding; n=6;
Proteobacteria|Rep: D-isomer specific 2-hydroxyacid
dehydrogenase, catalytic region:D- isomer specific
2-hydroxyacid dehydrogenase, NAD-binding - Ralstonia
eutropha (strain JMP134) (Alcaligenes eutrophus)
Length = 312
Score = 67.3 bits (157), Expect = 5e-10
Identities = 36/79 (45%), Positives = 47/79 (59%)
Frame = +1
Query: 235 LLMEIPNHDALVVRSATQVTKEVLDAGVKLKVVGRAGAGVDNIDVXSAGKKGVGVINAPG 414
LL + DAL+VR+ TQV +L+ L+VVGR G G+DNIDV + +G+ VI A G
Sbjct: 38 LLDALAGADALIVRNRTQVDAALLERAPALRVVGRLGVGLDNIDVAACRDRGIRVIPASG 97
Query: 415 ANALSACELTCTLMLVLAR 471
ANA S E T +L R
Sbjct: 98 ANARSVAEYVVTTAALLLR 116
>UniRef50_Q7WM64 Cluster: Putative dehydrogenase; n=2;
Bordetella|Rep: Putative dehydrogenase - Bordetella
bronchiseptica (Alcaligenes bronchisepticus)
Length = 330
Score = 66.9 bits (156), Expect = 6e-10
Identities = 37/115 (32%), Positives = 61/115 (53%)
Frame = +1
Query: 142 LIVDGVGAKCAELLNAYGIATTTKAKISKEELLMEIPNHDALVVRSATQVTKEVLDAGVK 321
LIV + + LL G+ A + ++ I + DA + R+A T+ + +AG +
Sbjct: 9 LIVQPIHEEGLALLREAGVECIAPASAAMADVAAAIADCDAAITRNAGLDTRAI-EAGRR 67
Query: 322 LKVVGRAGAGVDNIDVXSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVQL 486
L+V+G G G + ID+ +A + G+ V+N PGANA S EL + + L + V L
Sbjct: 68 LRVIGNHGTGTNMIDLAAAERLGIPVVNTPGANARSVAELALAMAMALLKRTVPL 122
>UniRef50_A6DQ00 Cluster: SerA; n=1; Lentisphaera araneosa
HTCC2155|Rep: SerA - Lentisphaera araneosa HTCC2155
Length = 522
Score = 66.9 bits (156), Expect = 6e-10
Identities = 38/117 (32%), Positives = 61/117 (52%)
Frame = +1
Query: 133 KSVLIVDGVGAKCAELLNAYGIATTTKAKISKEELLMEIPNHDALVVRSATQVTKEVLDA 312
+ VLI + ++L G +A + EL P+ + ++VRS ++T EV+D
Sbjct: 3 QKVLIPTKLSTAAKDILEGNGFTVVQEAGVDLVELAKAHPDTEGMIVRSE-KLTPEVIDL 61
Query: 313 GVKLKVVGRAGAGVDNIDVXSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVQ 483
LK V RAGAG + ID+ A K + V+N PGAN+ + E +M+ AR ++
Sbjct: 62 FPNLKAVVRAGAGYNTIDIQYARSKDITVMNTPGANSNAVAEEAVGMMISCARFFIE 118
>UniRef50_Q03WU1 Cluster: Lactate dehydrogenase related
dehydrogenase; n=1; Leuconostoc mesenteroides subsp.
mesenteroides ATCC 8293|Rep: Lactate dehydrogenase
related dehydrogenase - Leuconostoc mesenteroides subsp.
mesenteroides (strain ATCC 8293 /NCDO 523)
Length = 312
Score = 66.5 bits (155), Expect = 8e-10
Identities = 35/85 (41%), Positives = 49/85 (57%)
Frame = +1
Query: 229 EELLMEIPNHDALVVRSATQVTKEVLDAGVKLKVVGRAGAGVDNIDVXSAGKKGVGVINA 408
E+ L+ + + A+++ + K DA LK++ R G G DNI V SA K GV V N
Sbjct: 35 EKKLLSLASDAAVIIMTDMAFDKNWFDALPNLKLIARRGVGYDNIPVESATKHGVWVTNT 94
Query: 409 PGANALSACELTCTLMLVLARHVVQ 483
PGANA++ EL TL+L + R V Q
Sbjct: 95 PGANAIAVAELAVTLILTVLRKVNQ 119
>UniRef50_O58320 Cluster: Glyoxylate reductase; n=16; cellular
organisms|Rep: Glyoxylate reductase - Pyrococcus
horikoshii
Length = 334
Score = 65.7 bits (153), Expect = 1e-09
Identities = 33/89 (37%), Positives = 50/89 (56%)
Frame = +1
Query: 217 KISKEELLMEIPNHDALVVRSATQVTKEVLDAGVKLKVVGRAGAGVDNIDVXSAGKKGVG 396
+I +E LL ++ DALV + ++ KEV + KL++V G DNID+ A K+G+
Sbjct: 33 EIPREILLKKVKEVDALVTMLSERIDKEVFENAPKLRIVANYAVGYDNIDIEEATKRGIY 92
Query: 397 VINAPGANALSACELTCTLMLVLARHVVQ 483
V N P + +L L+L ARHVV+
Sbjct: 93 VTNTPDVLTDATADLAFALLLATARHVVK 121
>UniRef50_Q64UR3 Cluster: D-3-phosphoglycerate dehydrogenase; n=10;
cellular organisms|Rep: D-3-phosphoglycerate
dehydrogenase - Bacteroides fragilis
Length = 306
Score = 65.3 bits (152), Expect = 2e-09
Identities = 34/83 (40%), Positives = 53/83 (63%)
Frame = +1
Query: 226 KEELLMEIPNHDALVVRSATQVTKEVLDAGVKLKVVGRAGAGVDNIDVXSAGKKGVGVIN 405
K +LL + + +A+++RS + EVLDA +LK+V RAGAG DN+D+ +A GV V+N
Sbjct: 39 KAQLLDAVKDANAIIIRSDI-IDAEVLDAAKELKIVVRAGAGYDNVDLNAATAHGVCVMN 97
Query: 406 APGANALSACELTCTLMLVLARH 474
PG N+ + EL L++ R+
Sbjct: 98 TPGQNSNAVAELVFGLLVYAVRN 120
>UniRef50_A1AR04 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase, NAD-binding; n=1; Pelobacter propionicus
DSM 2379|Rep: D-isomer specific 2-hydroxyacid
dehydrogenase, NAD-binding - Pelobacter propionicus
(strain DSM 2379)
Length = 357
Score = 65.3 bits (152), Expect = 2e-09
Identities = 37/120 (30%), Positives = 64/120 (53%)
Frame = +1
Query: 124 VDIKSVLIVDGVGAKCAELLNAYGIATTTKAKISKEELLMEIPNHDALVVRSATQVTKEV 303
V +VLI + + E L S+E L I + +ALV RS +V+ ++
Sbjct: 20 VHTMNVLIASSIDGEAIERLEQEHQVIRAFPNSSEESLHALIRDCEALVFRSGIRVSADL 79
Query: 304 LDAGVKLKVVGRAGAGVDNIDVXSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVQ 483
+ +LK++ RAG+G+DN+DV A K+GV ++ P +A + E+ ML L+R +++
Sbjct: 80 MGCAPRLKLLVRAGSGMDNLDVEYARKRGVQLVRIPQPSARAVAEMAFAFMLALSRRLLE 139
>UniRef50_A0VQR0 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase, NAD-binding; n=1; Dinoroseobacter shibae
DFL 12|Rep: D-isomer specific 2-hydroxyacid
dehydrogenase, NAD-binding - Dinoroseobacter shibae DFL
12
Length = 316
Score = 65.3 bits (152), Expect = 2e-09
Identities = 31/78 (39%), Positives = 46/78 (58%)
Frame = +1
Query: 238 LMEIPNHDALVVRSATQVTKEVLDAGVKLKVVGRAGAGVDNIDVXSAGKKGVGVINAPGA 417
L+ + D ++VR+ TQV + LDA +L+V+G G G+DNID+ + +G+ V A GA
Sbjct: 39 LVAVARADGVIVRNRTQVDRPFLDAASRLRVIGLLGTGLDNIDMAACAARGISVHPATGA 98
Query: 418 NALSACELTCTLMLVLAR 471
N S E T L+L R
Sbjct: 99 NTRSVAEYVITAALMLTR 116
>UniRef50_P0A9T3 Cluster: D-3-phosphoglycerate dehydrogenase; n=185;
Bacteria|Rep: D-3-phosphoglycerate dehydrogenase -
Shigella flexneri
Length = 410
Score = 65.3 bits (152), Expect = 2e-09
Identities = 39/114 (34%), Positives = 61/114 (53%), Gaps = 2/114 (1%)
Frame = +1
Query: 142 LIVDGVGAKCAELLNAYGIATTT--KAKISKEELLMEIPNHDALVVRSATQVTKEVLDAG 315
L+V+GV K E L A G K + E+L I + + +RS T +T++V++A
Sbjct: 14 LLVEGVHQKALESLRAAGYTNIEFHKGALDDEQLKESIRDAHFIGLRSRTHLTEDVINAA 73
Query: 316 VKLKVVGRAGAGVDNIDVXSAGKKGVGVINAPGANALSACELTCTLMLVLARHV 477
KL +G G + +D+ +A K+G+ V NAP +N S EL +L+L R V
Sbjct: 74 EKLVAIGCFCIGTNQVDLDAAAKRGIPVFNAPFSNTRSVAELVIGELLLLLRGV 127
>UniRef50_Q83AZ4 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase family protein; n=11; Bacteria|Rep:
D-isomer specific 2-hydroxyacid dehydrogenase family
protein - Coxiella burnetii
Length = 388
Score = 64.9 bits (151), Expect = 2e-09
Identities = 36/84 (42%), Positives = 51/84 (60%)
Frame = +1
Query: 226 KEELLMEIPNHDALVVRSATQVTKEVLDAGVKLKVVGRAGAGVDNIDVXSAGKKGVGVIN 405
K LL E DA++VRS K++ D +++V+GRAG GV+NI V GV V+N
Sbjct: 23 KYTLLTECEEPDAILVRSCNLHDKKIAD---RVQVIGRAGVGVNNIPVRPLTLSGVPVLN 79
Query: 406 APGANALSACELTCTLMLVLARHV 477
PGANA + EL T +L+ +RH+
Sbjct: 80 TPGANANAVKELVITGILLASRHI 103
Score = 37.5 bits (83), Expect = 0.43
Identities = 25/82 (30%), Positives = 36/82 (43%), Gaps = 2/82 (2%)
Frame = +3
Query: 525 YTGSELAGXXLXILGLGRVGXXVATXMYAFXMNIIGFQPFRVC*SVRPVPLHXXGAGGXF 704
++G EL G L I+GLG++G VA M IG+ P S + A
Sbjct: 131 FSGFELPGKTLGIIGLGQIGVKVANAAIRLGMKAIGYDPAITVRSAWELSSEVAQAESLR 190
Query: 705 GPL--TDXITLHTPVIEXTXXL 764
L +D +T+H P+ T L
Sbjct: 191 DVLRNSDFVTVHVPLNTHTHHL 212
>UniRef50_Q67M76 Cluster: Phosphoglycerate dehydrogenase, N-terminal
domain; n=1; Symbiobacterium thermophilum|Rep:
Phosphoglycerate dehydrogenase, N-terminal domain -
Symbiobacterium thermophilum
Length = 140
Score = 64.9 bits (151), Expect = 2e-09
Identities = 33/86 (38%), Positives = 53/86 (61%)
Frame = +1
Query: 223 SKEELLMEIPNHDALVVRSATQVTKEVLDAGVKLKVVGRAGAGVDNIDVXSAGKKGVGVI 402
S ++ E+ A++VR A T+E+++A L+V+ + G GVDNIDV +A ++G+ V+
Sbjct: 34 SPAAVIPELDGVQAIIVRLAP-CTREIIEAAPDLRVIAKHGVGVDNIDVAAATERGILVL 92
Query: 403 NAPGANALSACELTCTLMLVLARHVV 480
N P ANA+S E + LA+ VV
Sbjct: 93 NTPEANAVSVAEHAIAAIAALAKRVV 118
>UniRef50_A6T665 Cluster: Putative D-3-phosphoglycerate
dehydrogenase; n=1; Klebsiella pneumoniae subsp.
pneumoniae MGH 78578|Rep: Putative D-3-phosphoglycerate
dehydrogenase - Klebsiella pneumoniae subsp. pneumoniae
MGH 78578
Length = 342
Score = 64.5 bits (150), Expect = 3e-09
Identities = 38/95 (40%), Positives = 56/95 (58%)
Frame = +1
Query: 211 KAKISKEELLMEIPNHDALVVRSATQVTKEVLDAGVKLKVVGRAGAGVDNIDVXSAGKKG 390
K K+S +L+ E+ + ++V S +VT V+ A +L+V+ A NID +A +G
Sbjct: 31 KPKLSAGQLI-ELAHDAEVLVTSYDEVTDAVMAACPRLQVIACTRANPVNIDTQAAQARG 89
Query: 391 VGVINAPGANALSACELTCTLMLVLARHVVQLHCA 495
+ V+ PG NA +A ELT LML LARH+ Q H A
Sbjct: 90 IRVLYTPGRNADAAAELTLGLMLSLARHIPQSHAA 124
Score = 33.1 bits (72), Expect = 9.3
Identities = 15/41 (36%), Positives = 22/41 (53%)
Frame = +3
Query: 522 LYTGSELAGXXLXILGLGRVGXXVATXMYAFXMNIIGFQPF 644
++ GSEL L ++G G +G VA AF M ++ PF
Sbjct: 160 VFKGSELRNKTLGLVGYGNIGRRVARIARAFGMAVLVVDPF 200
>UniRef50_Q4WHR3 Cluster: D-3-phosphoglycerate dehydrogenase; n=1;
Aspergillus fumigatus|Rep: D-3-phosphoglycerate
dehydrogenase - Aspergillus fumigatus (Sartorya
fumigata)
Length = 635
Score = 64.5 bits (150), Expect = 3e-09
Identities = 47/137 (34%), Positives = 69/137 (50%), Gaps = 24/137 (17%)
Frame = +1
Query: 139 VLIVDGVGAKCAELLNAYGIATTTKAKISKEELLMEIPNHDALVVRSATQVTKEVLDAGV 318
VL+ + + LL A + + + +ELL IP ++ALVVRS T+VT +L A
Sbjct: 11 VLVPEKLSPDGLALLRA-SLEVDERRGLDADELLQIIPEYEALVVRSETKVTANLLRAAK 69
Query: 319 KLKVVGRAGAGVDNI------------------------DVXSAGKKGVGVINAPGANAL 426
+LKVV RAG GVDN+ DV A K G+ V+N+P N
Sbjct: 70 QLKVVARAGVGVDNVGELAQPPLPPSPSLGSWPLTSHRTDVEEATKLGIVVVNSPSGNIG 129
Query: 427 SACELTCTLMLVLARHV 477
+A E T L++ +AR++
Sbjct: 130 AAAEHTIALLMAMARNI 146
>UniRef50_Q7X388 Cluster: Phosphoglycerate dehydrogenase; n=3;
Escherichia coli|Rep: Phosphoglycerate dehydrogenase -
Escherichia coli
Length = 306
Score = 64.1 bits (149), Expect = 4e-09
Identities = 33/90 (36%), Positives = 56/90 (62%)
Frame = +1
Query: 217 KISKEELLMEIPNHDALVVRSATQVTKEVLDAGVKLKVVGRAGAGVDNIDVXSAGKKGVG 396
+ SKEEL+ +I + +A++ + +++EV+D LKV+ + G G+DNIDV A K +
Sbjct: 37 RYSKEELIEKIKDANAIITGN-DPLSREVIDQAKNLKVISKYGVGLDNIDVDYANSKDIV 95
Query: 397 VINAPGANALSACELTCTLMLVLARHVVQL 486
V A AN++S E+T +ML +R V++
Sbjct: 96 VHKALNANSISVAEMTILMMLSSSRKYVEI 125
>UniRef50_Q1V300 Cluster: D-3-phosphoglycerate dehydrogenase; n=2;
Vibrio|Rep: D-3-phosphoglycerate dehydrogenase - Vibrio
alginolyticus 12G01
Length = 166
Score = 64.1 bits (149), Expect = 4e-09
Identities = 34/115 (29%), Positives = 64/115 (55%), Gaps = 2/115 (1%)
Frame = +1
Query: 139 VLIVDGVGAKCAELLNAYGIATTT--KAKISKEELLMEIPNHDALVVRSATQVTKEVLDA 312
+L+++G+ E+L A G K + +EEL+ + + + +RS T +++EV++A
Sbjct: 13 ILLLEGLHPSSVEVLQAAGYTNIEYHKGSLPEEELIEAVKDVHFIGIRSRTNLSEEVINA 72
Query: 313 GVKLKVVGRAGAGVDNIDVXSAGKKGVGVINAPGANALSACELTCTLMLVLARHV 477
KL +G G + +++ +A K+G+ V NAP +N S EL +L+L R +
Sbjct: 73 ANKLVAIGCFCIGTNQVNLDAAAKRGIPVFNAPFSNTRSVAELVLGQILLLVRGI 127
>UniRef50_A6PUG1 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase, NAD-binding; n=1; Victivallis vadensis
ATCC BAA-548|Rep: D-isomer specific 2-hydroxyacid
dehydrogenase, NAD-binding - Victivallis vadensis ATCC
BAA-548
Length = 524
Score = 64.1 bits (149), Expect = 4e-09
Identities = 36/117 (30%), Positives = 63/117 (53%)
Frame = +1
Query: 130 IKSVLIVDGVGAKCAELLNAYGIATTTKAKISKEELLMEIPNHDALVVRSATQVTKEVLD 309
++ VLI + A +L+ G +L+ + + L+VRS ++T E++D
Sbjct: 1 MRKVLIPTKLDKFAATMLSDRGYNVVLDGATPLADLVKANSDAEVLIVRSE-KITPEIID 59
Query: 310 AGVKLKVVGRAGAGVDNIDVXSAGKKGVGVINAPGANALSACELTCTLMLVLARHVV 480
+LK++ RAGAG + ID+ A K + V+N PGAN+ + E +ML +RH++
Sbjct: 60 LLPQLKLIVRAGAGFNTIDIKYARKHDIDVMNTPGANSNAVAEEVVAMMLAASRHLI 116
>UniRef50_A1HSQ7 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase, NAD-binding; n=1; Thermosinus
carboxydivorans Nor1|Rep: D-isomer specific
2-hydroxyacid dehydrogenase, NAD-binding - Thermosinus
carboxydivorans Nor1
Length = 317
Score = 64.1 bits (149), Expect = 4e-09
Identities = 36/90 (40%), Positives = 54/90 (60%), Gaps = 1/90 (1%)
Frame = +1
Query: 220 ISKEELLMEIPNHDALVVRSATQVTKEVLDAGVK-LKVVGRAGAGVDNIDVXSAGKKGVG 396
++++EL+ I DALV VT +V+ AG+ LK++ + G G + IDV +A G+
Sbjct: 37 LTEDELVELIKGMDALVA-GMDAVTAKVIAAGLPTLKIIAKHGVGYNTIDVAAAAAYGIP 95
Query: 397 VINAPGANALSACELTCTLMLVLARHVVQL 486
V PGAN +S EL LML +ARH+ Q+
Sbjct: 96 VTITPGANNISVAELAIGLMLAVARHIPQM 125
Score = 39.1 bits (87), Expect = 0.14
Identities = 18/36 (50%), Positives = 23/36 (63%)
Frame = +3
Query: 528 TGSELAGXXLXILGLGRVGXXVATXMYAFXMNIIGF 635
TGSEL G L I+G+G +G VA +AF M II +
Sbjct: 138 TGSELYGKVLGIIGMGSIGCEVAKRAHAFGMKIIAY 173
>UniRef50_Q9TXJ5 Cluster: D-3-phosphoglycerate dehydrogenase-like
protein; n=10; cellular organisms|Rep:
D-3-phosphoglycerate dehydrogenase-like protein -
Leishmania major
Length = 511
Score = 63.7 bits (148), Expect = 6e-09
Identities = 40/115 (34%), Positives = 62/115 (53%), Gaps = 1/115 (0%)
Frame = +1
Query: 142 LIVDGVGAKCAELLNAYG-IATTTKAKISKEELLMEIPNHDALVVRSATQVTKEVLDAGV 318
L+++GV ELL + G I + ++ LL +I + L +RS TQVT+ +LDA
Sbjct: 116 LLLEGVNPIAKELLESKGCIVEYIPNALPRDTLLEKIRDVHFLGIRSKTQVTQAILDAAP 175
Query: 319 KLKVVGRAGAGVDNIDVXSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVQ 483
KL +G G + +D+ A +GV V N+P AN S EL ++ L+R + Q
Sbjct: 176 KLLGIGCFCIGTNQVDLDYATTRGVAVFNSPFANTRSVAELVIGEIISLSRKMTQ 230
>UniRef50_Q7D366 Cluster: AGR_pAT_578p; n=2; Agrobacterium
tumefaciens str. C58|Rep: AGR_pAT_578p - Agrobacterium
tumefaciens (strain C58 / ATCC 33970)
Length = 317
Score = 63.3 bits (147), Expect = 8e-09
Identities = 34/89 (38%), Positives = 50/89 (56%)
Frame = +1
Query: 229 EELLMEIPNHDALVVRSATQVTKEVLDAGVKLKVVGRAGAGVDNIDVXSAGKKGVGVINA 408
+EL + + DA++ T + V + +LK + R G GVDNID+ +A + G+ V NA
Sbjct: 42 DELSARLGDVDAVIAGVDTW-NERVFNLAPRLKAIARFGVGVDNIDIDAAHRHGIAVTNA 100
Query: 409 PGANALSACELTCTLMLVLARHVVQLHCA 495
PG NA + ELT L+L R + LH A
Sbjct: 101 PGGNANAVAELTLGLILSAMRRIPYLHDA 129
>UniRef50_Q1FF19 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase, catalytic region:D- isomer specific
2-hydroxyacid dehydrogenase, NAD-binding; n=1;
Clostridium phytofermentans ISDg|Rep: D-isomer specific
2-hydroxyacid dehydrogenase, catalytic region:D- isomer
specific 2-hydroxyacid dehydrogenase, NAD-binding -
Clostridium phytofermentans ISDg
Length = 316
Score = 63.3 bits (147), Expect = 8e-09
Identities = 41/114 (35%), Positives = 55/114 (48%)
Frame = +1
Query: 139 VLIVDGVGAKCAELLNAYGIATTTKAKISKEELLMEIPNHDALVVRSATQVTKEVLDAGV 318
+LI V L G S E + I + L++R+ TKEV DA
Sbjct: 5 ILIPQDVDESGKNYLQEKGYELRILQDSSIENICNNIGDCSGLLLRTVP-CTKEVFDAAP 63
Query: 319 KLKVVGRAGAGVDNIDVXSAGKKGVGVINAPGANALSACELTCTLMLVLARHVV 480
LKV+GR G G DNID+ A +G+ V P ANA S E T L+L A+++V
Sbjct: 64 HLKVIGRHGVGYDNIDIAEATAQGIKVCYTPLANANSVAEHTIMLLLACAKNIV 117
>UniRef50_A4YUP8 Cluster: Putative D-3-phosphoglycerate
dehydrogenase; n=1; Bradyrhizobium sp. ORS278|Rep:
Putative D-3-phosphoglycerate dehydrogenase -
Bradyrhizobium sp. (strain ORS278)
Length = 335
Score = 62.9 bits (146), Expect = 1e-08
Identities = 39/125 (31%), Positives = 64/125 (51%), Gaps = 5/125 (4%)
Frame = +1
Query: 127 DIKSVLIVDG--VGAKCAELLNAYGIATTTKAKISKEELLMEIPNH---DALVVRSATQV 291
D++ L++ G + A+ + G A + + + L EI D ++VR ++
Sbjct: 9 DMRYKLLITGPALTAEATAIAARRGAALVDNPRYASPQELAEITAREQPDGIIVRQG-KI 67
Query: 292 TKEVLDAGVKLKVVGRAGAGVDNIDVXSAGKKGVGVINAPGANALSACELTCTLMLVLAR 471
+V+ A KLK + + G G DNIDV +A ++G+ V A GAN+ S EL LM +AR
Sbjct: 68 DDQVIGASQKLKAIAKHGVGYDNIDVEAADRRGIPVFVARGANSQSVAELAFALMFAVAR 127
Query: 472 HVVQL 486
+ L
Sbjct: 128 EIPHL 132
>UniRef50_Q76KF5 Cluster: D-phosphoglycerate dehydrogenase; n=2;
Entamoeba histolytica|Rep: D-phosphoglycerate
dehydrogenase - Entamoeba histolytica
Length = 299
Score = 62.9 bits (146), Expect = 1e-08
Identities = 29/78 (37%), Positives = 50/78 (64%)
Frame = +1
Query: 226 KEELLMEIPNHDALVVRSATQVTKEVLDAGVKLKVVGRAGAGVDNIDVXSAGKKGVGVIN 405
KE+++ I + D ++VRS ++ +E++ AG K+K++ RAGAG DNID+ + + + V+N
Sbjct: 39 KEDVIERIKDADGVIVRS-DKIDEEIIKAGEKVKIIVRAGAGYDNIDIEACNQGKIVVMN 97
Query: 406 APGANALSACELTCTLML 459
PG N EL +M+
Sbjct: 98 TPGQNRNGVAELCIGMMI 115
>UniRef50_UPI0000E4762C Cluster: PREDICTED: similar to
D-3-phosphoglycerate dehydrogenase; n=1;
Strongylocentrotus purpuratus|Rep: PREDICTED: similar to
D-3-phosphoglycerate dehydrogenase - Strongylocentrotus
purpuratus
Length = 493
Score = 56.0 bits (129), Expect = 1e-06
Identities = 37/98 (37%), Positives = 46/98 (46%)
Frame = +3
Query: 516 RALYTGSELAGXXLXILGLGRVGXXVATXMYAFXMNIIGFQPFRVC*SVRPVPLHXXGAG 695
R + GSEL G L I+GLGR+G VA M +F M IGF P + +
Sbjct: 98 RKAFMGSELYGKTLGIVGLGRIGREVAQRMQSFGMTTIGFDPIVPAEEAKQYNIEWQTLE 157
Query: 696 GXFGPLTDXITLHTPVIEXTXXLYPXPMS*XQCXKGVK 809
+ P D IT+HTP+I T L S C GVK
Sbjct: 158 QMW-PRCDYITVHTPLIPQTKGLL-GDASFKLCKPGVK 193
Score = 48.4 bits (110), Expect(2) = 1e-08
Identities = 23/45 (51%), Positives = 27/45 (60%)
Frame = +1
Query: 118 MVVDIKSVLIVDGVGAKCAELLNAYGIATTTKAKISKEELLMEIP 252
M +K VLI D V +CAE+L GI K+SKEELL EIP
Sbjct: 1 MAFSLKKVLISDSVSPRCAEILRENGIEVDNNTKLSKEELLAEIP 45
Score = 33.9 bits (74), Expect(2) = 1e-08
Identities = 17/43 (39%), Positives = 22/43 (51%)
Frame = +1
Query: 361 IDVXSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVQLH 489
IDV + G PG N LSA E TC ++ L+R + Q H
Sbjct: 46 IDVYDYLRMAWGSTYTPGGNTLSAAEHTCAMVCCLSRSLPQAH 88
>UniRef50_Q0PQJ5 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase; n=1; Endoriftia persephone
'Hot96_1+Hot96_2'|Rep: D-isomer specific 2-hydroxyacid
dehydrogenase - Endoriftia persephone 'Hot96_1+Hot96_2'
Length = 204
Score = 62.1 bits (144), Expect = 2e-08
Identities = 36/101 (35%), Positives = 55/101 (54%)
Frame = +1
Query: 181 LNAYGIATTTKAKISKEELLMEIPNHDALVVRSATQVTKEVLDAGVKLKVVGRAGAGVDN 360
LN +A + E+ E+ + DA+++RS E+ ++ +GRAGAGV+N
Sbjct: 7 LNNISVAGLDRLPRDNYEVASEVAHPDAILLRSYKMHDMEIPKT---VQAIGRAGAGVNN 63
Query: 361 IDVXSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVQ 483
I V +G+ V NAPGANA + EL ML+ AR++ Q
Sbjct: 64 IPVDKMTARGISVFNAPGANANAVKELVVAGMLLAARNISQ 104
>UniRef50_Q0FX01 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase, NAD binding subunit; n=3;
Rhodobacteraceae|Rep: D-isomer specific 2-hydroxyacid
dehydrogenase, NAD binding subunit - Roseovarius sp.
HTCC2601
Length = 326
Score = 61.3 bits (142), Expect = 3e-08
Identities = 35/79 (44%), Positives = 45/79 (56%)
Frame = +1
Query: 259 DALVVRSATQVTKEVLDAGVKLKVVGRAGAGVDNIDVXSAGKKGVGVINAPGANALSACE 438
DALVV VT E L G KL+ V + G GVDNID+ + + G+ V N P ANA + E
Sbjct: 53 DALVV-GLVPVTPETLTQGGKLRAVIKHGVGVDNIDIPACTEAGLPVCNTPAANADAVAE 111
Query: 439 LTCTLMLVLARHVVQLHCA 495
L LM +AR + Q H +
Sbjct: 112 LAVGLMFSMARWIPQGHAS 130
>UniRef50_Q5KFZ5 Cluster: Phosphoglycerate dehydrogenase, putative;
n=2; Filobasidiella neoformans|Rep: Phosphoglycerate
dehydrogenase, putative - Cryptococcus neoformans
(Filobasidiella neoformans)
Length = 339
Score = 60.9 bits (141), Expect = 4e-08
Identities = 28/76 (36%), Positives = 47/76 (61%)
Frame = +1
Query: 259 DALVVRSATQVTKEVLDAGVKLKVVGRAGAGVDNIDVXSAGKKGVGVINAPGANALSACE 438
D +++R+ VT E++ A L+++ R G GVDN+ + + +G+ V N PG+NA + E
Sbjct: 59 DGILLRTG-DVTAEMVLAAPNLRIISRNGTGVDNVPLPTCLSRGIAVTNIPGSNAFAVAE 117
Query: 439 LTCTLMLVLARHVVQL 486
L LML + R VV++
Sbjct: 118 LAIALMLTVLRRVVEV 133
>UniRef50_UPI0000D9FBAD Cluster: PREDICTED: similar to
3-phosphoglycerate dehydrogenase, partial; n=1; Macaca
mulatta|Rep: PREDICTED: similar to 3-phosphoglycerate
dehydrogenase, partial - Macaca mulatta
Length = 333
Score = 60.5 bits (140), Expect = 5e-08
Identities = 38/111 (34%), Positives = 60/111 (54%)
Frame = +1
Query: 142 LIVDGVGAKCAELLNAYGIATTTKAKISKEELLMEIPNHDALVVRSATQVTKEVLDAGVK 321
+ VDG+ C + +G K ++EEL + +A +VRS ++ +E +
Sbjct: 71 IAVDGIEKICKDNGLTFGKIEGYK---TQEELYSAAESAEACIVRS-DKLDEEFFNRAKN 126
Query: 322 LKVVGRAGAGVDNIDVXSAGKKGVGVINAPGANALSACELTCTLMLVLARH 474
LK+V RAGAGVD ID+ +A K V V N PG NA + E+ L++ + R+
Sbjct: 127 LKIVVRAGAGVDTIDLDAASKHHVVVENTPGQNANAVAEMVFALLIAMKRN 177
>UniRef50_Q9WYG2 Cluster: Phosphoglycerate dehydrogenase, putative;
n=2; Thermotoga|Rep: Phosphoglycerate dehydrogenase,
putative - Thermotoga maritima
Length = 327
Score = 60.5 bits (140), Expect = 5e-08
Identities = 33/77 (42%), Positives = 47/77 (61%)
Frame = +1
Query: 259 DALVVRSATQVTKEVLDAGVKLKVVGRAGAGVDNIDVXSAGKKGVGVINAPGANALSACE 438
DAL+V VT E+++ LK++ + G GVDNID+ +A KKG+ V GAN+LS E
Sbjct: 44 DALIV-GTHPVTAEMVENS-SLKIIAKHGVGVDNIDLEAATKKGIPVTITAGANSLSVAE 101
Query: 439 LTCTLMLVLARHVVQLH 489
LT + L+R +V H
Sbjct: 102 LTIAFIFALSRGLVWAH 118
Score = 35.5 bits (78), Expect = 1.7
Identities = 20/75 (26%), Positives = 34/75 (45%)
Frame = +3
Query: 531 GSELAGXXLXILGLGRVGXXVATXMYAFXMNIIGFQPFRVC*SVRPVPLHXXGAGGXFGP 710
G E++G L ++G G +G V MN++ + P+ SVR +
Sbjct: 132 GQEVSGKTLGVVGFGSIGREVVKKAVCLGMNVLVYDPYVSKDSVRLLEATPVDDLEQLLK 191
Query: 711 LTDXITLHTPVIEXT 755
+D ++LH P+ E T
Sbjct: 192 ESDFVSLHVPLNEST 206
>UniRef50_Q1GAM7 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase; n=1; Lactobacillus delbrueckii subsp.
bulgaricus ATCC 11842|Rep: D-isomer specific
2-hydroxyacid dehydrogenase - Lactobacillus delbrueckii
subsp. bulgaricus (strain ATCC 11842 / DSM20081)
Length = 322
Score = 60.5 bits (140), Expect = 5e-08
Identities = 37/110 (33%), Positives = 55/110 (50%)
Frame = +1
Query: 142 LIVDGVGAKCAELLNAYGIATTTKAKISKEELLMEIPNHDALVVRSATQVTKEVLDAGVK 321
++V G+ + L T A K+ L + + DAL+ V +E+LDAG K
Sbjct: 12 VLVAGLAVRQLPELEKVCEVTFAPAGAGKDWYLANLGDFDALIT-GKLPVDQELLDAGKK 70
Query: 322 LKVVGRAGAGVDNIDVXSAGKKGVGVINAPGANALSACELTCTLMLVLAR 471
LK+V G G D+IDV A +G+ V N P + E+ TL+L L+R
Sbjct: 71 LKIVSATGVGYDHIDVDYASSQGIIVSNCPASVMQPTAEMAFTLLLALSR 120
>UniRef50_A3UGW9 Cluster: D-3-phosphoglycerate dehydrogenase; n=2;
Proteobacteria|Rep: D-3-phosphoglycerate dehydrogenase -
Oceanicaulis alexandrii HTCC2633
Length = 407
Score = 60.5 bits (140), Expect = 5e-08
Identities = 37/116 (31%), Positives = 59/116 (50%), Gaps = 2/116 (1%)
Frame = +1
Query: 136 SVLIVDGVGAKCAELLNAYGIATTTKAKISKE--ELLMEIPNHDALVVRSATQVTKEVLD 309
+ L+++ V L G T + S + +L EI + L +RS T V +LD
Sbjct: 8 TALLLENVHPDADNALQTAGPVTVKRLSGSPDRAQLESEIASASVLGIRSRTHVDAALLD 67
Query: 310 AGVKLKVVGRAGAGVDNIDVXSAGKKGVGVINAPGANALSACELTCTLMLVLARHV 477
A +L+ VG G + +D+ +A ++GV V NAP AN S ELT +++L R +
Sbjct: 68 AAKELQAVGCFCIGTNQVDLVAAAERGVPVFNAPFANTRSVAELTMASVIMLMRRI 123
>UniRef50_A1RDF9 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase family protein; n=1; Arthrobacter
aurescens TC1|Rep: D-isomer specific 2-hydroxyacid
dehydrogenase family protein - Arthrobacter aurescens
(strain TC1)
Length = 329
Score = 60.5 bits (140), Expect = 5e-08
Identities = 26/76 (34%), Positives = 49/76 (64%)
Frame = +1
Query: 253 NHDALVVRSATQVTKEVLDAGVKLKVVGRAGAGVDNIDVXSAGKKGVGVINAPGANALSA 432
N D +++R+ T T+E+++A +LK++ R G G DN+D+ +A + V V + PG+N+ +
Sbjct: 41 NIDGVILRAET-FTREMIEASPRLKIIARHGVGTDNVDIPAASEHSVWVTSTPGSNSNAV 99
Query: 433 CELTCTLMLVLARHVV 480
E +L+L L R ++
Sbjct: 100 AEHVFSLLLSLTRRII 115
Score = 36.7 bits (81), Expect = 0.76
Identities = 22/75 (29%), Positives = 30/75 (40%)
Frame = +3
Query: 531 GSELAGXXLXILGLGRVGXXVATXMYAFXMNIIGFQPFRVC*SVRPVPLHXXGAGGXFGP 710
G EL+G L I+G G +G VAT F M ++ P +
Sbjct: 135 GFELSGRTLGIVGFGAIGKRVATIANGFGMRVLASDPIATAADAEAAGAVLVELDTLYDG 194
Query: 711 LTDXITLHTPVIEXT 755
D ITLH P++ T
Sbjct: 195 -ADIITLHAPLLSGT 208
>UniRef50_A1HMI9 Cluster: Phosphoglycerate dehydrogenase; n=1;
Thermosinus carboxydivorans Nor1|Rep: Phosphoglycerate
dehydrogenase - Thermosinus carboxydivorans Nor1
Length = 326
Score = 60.5 bits (140), Expect = 5e-08
Identities = 32/101 (31%), Positives = 56/101 (55%)
Frame = +1
Query: 175 ELLNAYGIATTTKAKISKEELLMEIPNHDALVVRSATQVTKEVLDAGVKLKVVGRAGAGV 354
E + G+ T ++ +E + + D +V + ++T+E++ KLK++ + G GV
Sbjct: 19 ESIKPSGVTVTYWYTLNDKEKEQALNSADYFLV-ALYKITQELIQKAPKLKMIQKTGVGV 77
Query: 355 DNIDVXSAGKKGVGVINAPGANALSACELTCTLMLVLARHV 477
DNID+ +A G+ V N PG NA S ELT +++ L R +
Sbjct: 78 DNIDLAAAKTLGIPVANTPGGNATSVAELTLGMIINLYRKI 118
>UniRef50_Q87MN8 Cluster: Erythronate-4-phosphate dehydrogenase;
n=17; Vibrio|Rep: Erythronate-4-phosphate dehydrogenase
- Vibrio parahaemolyticus
Length = 377
Score = 60.5 bits (140), Expect = 5e-08
Identities = 37/110 (33%), Positives = 58/110 (52%)
Frame = +1
Query: 142 LIVDGVGAKCAELLNAYGIATTTKAKISKEELLMEIPNHDALVVRSATQVTKEVLDAGVK 321
+IVD EL + G + + L++I DAL++RS T+V E++ K
Sbjct: 3 IIVDENMPYAEELFSQLGEVILKPGRTLTADDLIDI---DALMIRSVTKVNAELISKANK 59
Query: 322 LKVVGRAGAGVDNIDVXSAGKKGVGVINAPGANALSACELTCTLMLVLAR 471
LK VG A AG+D++D +KG+ APG N + E ++M+VLA+
Sbjct: 60 LKFVGTATAGMDHVDQALLKEKGIFFTAAPGCNKVGVAEYAFSVMMVLAQ 109
>UniRef50_A0LN07 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase, NAD-binding; n=1; Syntrophobacter
fumaroxidans MPOB|Rep: D-isomer specific 2-hydroxyacid
dehydrogenase, NAD-binding - Syntrophobacter
fumaroxidans (strain DSM 10017 / MPOB)
Length = 317
Score = 60.1 bits (139), Expect = 7e-08
Identities = 31/113 (27%), Positives = 64/113 (56%)
Frame = +1
Query: 139 VLIVDGVGAKCAELLNAYGIATTTKAKISKEELLMEIPNHDALVVRSATQVTKEVLDAGV 318
+L+ + + A+ E+L A + ++ L+ + + D +++R+ VT+ ++++
Sbjct: 7 ILLYESMHARGTEVL-AEKCELVYATSLDEKNLIAQAADVDGIIIRANGAVTRALIESAP 65
Query: 319 KLKVVGRAGAGVDNIDVXSAGKKGVGVINAPGANALSACELTCTLMLVLARHV 477
+LKV+GR G G+D ID+ A ++GV V+ P AN S E + ++LA+ +
Sbjct: 66 RLKVIGRHGVGLDAIDLRCAKERGVKVVFTPTANTESVAEHFVGMAIMLAKMI 118
>UniRef50_Q65WI5 Cluster: SerA protein; n=1; Mannheimia
succiniciproducens MBEL55E|Rep: SerA protein -
Mannheimia succiniciproducens (strain MBEL55E)
Length = 326
Score = 59.7 bits (138), Expect = 9e-08
Identities = 36/108 (33%), Positives = 60/108 (55%)
Frame = +1
Query: 160 GAKCAELLNAYGIATTTKAKISKEELLMEIPNHDALVVRSATQVTKEVLDAGVKLKVVGR 339
G K E NA +A T + + +L E+ + + L++R + + +E + LKV+GR
Sbjct: 15 GMKVLEDANAQ-VAITNDG--NPKIMLPELLDAEGLIIRIGS-IDRETMLQAKNLKVIGR 70
Query: 340 AGAGVDNIDVXSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVQ 483
G GVD++DV +A + G+ V+ APG+N S E LM A+ +V+
Sbjct: 71 PGVGVDDVDVKTATELGIPVVIAPGSNTRSVAEHAFALMFACAKDIVR 118
>UniRef50_A0V9Y4 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase, NAD-binding; n=2; Comamonadaceae|Rep:
D-isomer specific 2-hydroxyacid dehydrogenase,
NAD-binding - Delftia acidovorans SPH-1
Length = 354
Score = 59.7 bits (138), Expect = 9e-08
Identities = 31/73 (42%), Positives = 45/73 (61%)
Frame = +1
Query: 259 DALVVRSATQVTKEVLDAGVKLKVVGRAGAGVDNIDVXSAGKKGVGVINAPGANALSACE 438
DA++ R+AT ++ + A LKV+ + G GV NIDV +A ++G+ V PGANA S E
Sbjct: 75 DAVISRTAT-LSAAAIAACPTLKVISKHGVGVSNIDVAAASQRGIPVYVTPGANAQSVAE 133
Query: 439 LTCTLMLVLARHV 477
+T LM AR +
Sbjct: 134 MTLGLMFAAARRI 146
Score = 41.5 bits (93), Expect = 0.027
Identities = 29/91 (31%), Positives = 41/91 (45%), Gaps = 4/91 (4%)
Frame = +3
Query: 504 AGGXRALYTGSELAGXXLXILGLGRVGXXVATXMYAFXMNIIGFQP-FRVC*SVRP---V 671
AG G EL+G L +LG G+VG VA A M ++ F P F + P
Sbjct: 155 AGRWSRAQDGLELSGRTLGLLGFGQVGQRVARVALALGMQVVAFDPAFDPACAPGPGAVA 214
Query: 672 PLHXXGAGGXFGPLTDXITLHTPVIEXTXXL 764
+ G+ PL+D ++LH P+ T L
Sbjct: 215 GVRMLGSVDELLPLSDVLSLHLPLNARTRHL 245
>UniRef50_Q8ZXX8 Cluster: D-3-phosphoglycerate dehydrogenase; n=1;
Pyrobaculum aerophilum|Rep: D-3-phosphoglycerate
dehydrogenase - Pyrobaculum aerophilum
Length = 323
Score = 59.7 bits (138), Expect = 9e-08
Identities = 33/86 (38%), Positives = 48/86 (55%)
Frame = +1
Query: 220 ISKEELLMEIPNHDALVVRSATQVTKEVLDAGVKLKVVGRAGAGVDNIDVXSAGKKGVGV 399
+ KE L+ +ALV+ + KEVLDAG KLK+V A GVD+IDV A +KGV V
Sbjct: 40 VPKEVLIDAARRCEALVIFIGDVIDKEVLDAGEKLKIVSTASVGVDHIDVEYAKRKGVVV 99
Query: 400 INAPGANALSACELTCTLMLVLARHV 477
+ P + +L L++ + R +
Sbjct: 100 AHTPYVLVDAVADLAVGLLIAVTRKI 125
>UniRef50_Q3CIY1 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase, catalytic region:D- isomer specific
2-hydroxyacid dehydrogenase, NAD-binding; n=2;
Thermoanaerobacter ethanolicus|Rep: D-isomer specific
2-hydroxyacid dehydrogenase, catalytic region:D- isomer
specific 2-hydroxyacid dehydrogenase, NAD-binding -
Thermoanaerobacter ethanolicus ATCC 33223
Length = 319
Score = 59.3 bits (137), Expect = 1e-07
Identities = 36/105 (34%), Positives = 59/105 (56%)
Frame = +1
Query: 169 CAELLNAYGIATTTKAKISKEELLMEIPNHDALVVRSATQVTKEVLDAGVKLKVVGRAGA 348
C +LN +G T EE++ + DAL+V + +V +V+ +LK++ + G
Sbjct: 29 CEVVLNPFGRPFTN------EEIIRYASDADALIVGN-DKVPGDVIKKCKRLKIIAKHGV 81
Query: 349 GVDNIDVXSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVQ 483
GVD+IDV +A + G+ V NAPG N+ +L L+ +LAR + Q
Sbjct: 82 GVDSIDVKTANQLGIVVTNAPGTNSEEVADLAFGLLHMLARGLYQ 126
>UniRef50_Q9UYH9 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase; n=4; Thermococcaceae|Rep: D-isomer
specific 2-hydroxyacid dehydrogenase - Pyrococcus abyssi
Length = 333
Score = 59.3 bits (137), Expect = 1e-07
Identities = 28/85 (32%), Positives = 48/85 (56%)
Frame = +1
Query: 223 SKEELLMEIPNHDALVVRSATQVTKEVLDAGVKLKVVGRAGAGVDNIDVXSAGKKGVGVI 402
S+EEL IP D +++ T++TK++L+ +LKV+ AG D++DV A K+G+ V
Sbjct: 32 SEEELKEIIPELDGIIIAPVTRITKDILERAERLKVISCQSAGYDHVDVEEATKRGIYVT 91
Query: 403 NAPGANALSACELTCTLMLVLARHV 477
G + + E L++ L R +
Sbjct: 92 KVSGLLSEAVAEFALGLLISLMRKI 116
>UniRef50_Q7WEA3 Cluster: Phosphoglycerate dehydrogenase; n=1;
Bordetella bronchiseptica|Rep: Phosphoglycerate
dehydrogenase - Bordetella bronchiseptica (Alcaligenes
bronchisepticus)
Length = 329
Score = 58.8 bits (136), Expect = 2e-07
Identities = 39/107 (36%), Positives = 50/107 (46%)
Frame = +1
Query: 175 ELLNAYGIATTTKAKISKEELLMEIPNHDALVVRSATQVTKEVLDAGVKLKVVGRAGAGV 354
+LL A GI A + L I DA++VR Q+ E++D +L V+ G G
Sbjct: 16 QLLRAAGITVIEPAGPGLDALRQVIAGADAVLVRD--QLPAELIDMAPRLCVIANHGTGT 73
Query: 355 DNIDVXSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVQLHCA 495
D I V A G+ V+ P AN S E LMLV AR VQ A
Sbjct: 74 DKIAVAHADALGIPVVYTPQANVRSVAEHALMLMLVTARQAVQADAA 120
>UniRef50_Q5FUD9 Cluster: D-3-phosphoglycerate dehydrogenase; n=1;
Gluconobacter oxydans|Rep: D-3-phosphoglycerate
dehydrogenase - Gluconobacter oxydans (Gluconobacter
suboxydans)
Length = 314
Score = 58.8 bits (136), Expect = 2e-07
Identities = 34/105 (32%), Positives = 54/105 (51%)
Frame = +1
Query: 181 LNAYGIATTTKAKISKEELLMEIPNHDALVVRSATQVTKEVLDAGVKLKVVGRAGAGVDN 360
LN GI T + E ++ E+ + DA++ R + E LDA LK++ G+G +
Sbjct: 18 LNNAGIRTRYATAPTMEAVIREVGDADAVITRDLG-FSAEALDAAPNLKIISCHGSGTNR 76
Query: 361 IDVXSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVQLHCA 495
I +A +GV V NAP N+ S E+T L+L + R + + A
Sbjct: 77 IAKAAAAARGVLVTNAPNTNSRSVAEMTIGLLLAVVRRLCEADLA 121
>UniRef50_Q3KBX8 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase, NAD-binding; n=2; Pseudomonas|Rep:
D-isomer specific 2-hydroxyacid dehydrogenase,
NAD-binding - Pseudomonas fluorescens (strain PfO-1)
Length = 324
Score = 58.8 bits (136), Expect = 2e-07
Identities = 33/79 (41%), Positives = 47/79 (59%), Gaps = 1/79 (1%)
Frame = +1
Query: 244 EIPNH-DALVVRSATQVTKEVLDAGVKLKVVGRAGAGVDNIDVXSAGKKGVGVINAPGAN 420
EI N DA+ +R ++ E++ A KL++V R GAG DN+D +A + GV V N PGAN
Sbjct: 37 EIQNEVDAVFLRGG-HISAEMIAASPKLRIVARHGAGYDNVDYKAAAELGVWVTNTPGAN 95
Query: 421 ALSACELTCTLMLVLARHV 477
S E L+L ++R V
Sbjct: 96 RRSVVEHVFALLLGISRKV 114
>UniRef50_A4R1I1 Cluster: Putative uncharacterized protein; n=1;
Magnaporthe grisea|Rep: Putative uncharacterized protein
- Magnaporthe grisea (Rice blast fungus) (Pyricularia
grisea)
Length = 421
Score = 58.8 bits (136), Expect = 2e-07
Identities = 34/118 (28%), Positives = 64/118 (54%), Gaps = 1/118 (0%)
Frame = +1
Query: 127 DIKSVLIVDGVGAKCAELLNAYGIATTT-KAKISKEELLMEIPNHDALVVRSATQVTKEV 303
DIK +L+++ V ++L G K + +++L+ +I + + +RS T+++++V
Sbjct: 62 DIK-ILLLENVNQSGQDILREQGYQVEAHKTSLPEDQLIEKIRSVHVIGIRSKTRLSEKV 120
Query: 304 LDAGVKLKVVGRAGAGVDNIDVXSAGKKGVGVINAPGANALSACELTCTLMLVLARHV 477
L L VVG G + +D+ A + G+ V N+P AN+ S EL ++ LAR +
Sbjct: 121 LREAKNLLVVGCFCIGTNQVDLEYAARHGIAVFNSPFANSRSVAELVIAEIITLARQL 178
>UniRef50_Q8ECR2 Cluster: Erythronate-4-phosphate dehydrogenase;
n=20; Shewanella|Rep: Erythronate-4-phosphate
dehydrogenase - Shewanella oneidensis
Length = 376
Score = 58.8 bits (136), Expect = 2e-07
Identities = 30/75 (40%), Positives = 43/75 (57%)
Frame = +1
Query: 244 EIPNHDALVVRSATQVTKEVLDAGVKLKVVGRAGAGVDNIDVXSAGKKGVGVINAPGANA 423
++ + D L+VRS T+V +L+A KLK VG A G D++D+ +G+ NAPG NA
Sbjct: 34 QVQDADVLLVRSVTRVNAALLEANQKLKFVGSATIGTDHVDLAYLATRGIVFSNAPGCNA 93
Query: 424 LSACELTCTLMLVLA 468
+ E ML LA
Sbjct: 94 TAVGEFAFIAMLELA 108
>UniRef50_Q47XK1 Cluster: Erythronate-4-phosphate dehydrogenase;
n=1; Colwellia psychrerythraea 34H|Rep:
Erythronate-4-phosphate dehydrogenase - Colwellia
psychrerythraea (strain 34H / ATCC BAA-681)
(Vibriopsychroerythus)
Length = 393
Score = 58.8 bits (136), Expect = 2e-07
Identities = 30/82 (36%), Positives = 50/82 (60%), Gaps = 1/82 (1%)
Frame = +1
Query: 244 EIPNHDALVVRSATQVTKEVLDAGVKLKVVGRAGAGVDNIDVXSAGKKGVGVINAPGANA 423
++ + D L+VRS TQV +++L K+ VG A G D+ID+ K+ + +APG NA
Sbjct: 46 QVADADVLLVRSITQVNEQLLHLNDKISFVGSATIGTDHIDLSYLAKRNITFQSAPGCNA 105
Query: 424 LSACELTCTLMLVLA-RHVVQL 486
+S E + ++VLA R+++ L
Sbjct: 106 ISVAEYVLSALVVLAERYLLTL 127
>UniRef50_A0HBX6 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase, NAD-binding; n=1; Comamonas testosteroni
KF-1|Rep: D-isomer specific 2-hydroxyacid dehydrogenase,
NAD-binding - Comamonas testosteroni KF-1
Length = 320
Score = 58.4 bits (135), Expect = 2e-07
Identities = 32/75 (42%), Positives = 45/75 (60%)
Frame = +1
Query: 262 ALVVRSATQVTKEVLDAGVKLKVVGRAGAGVDNIDVXSAGKKGVGVINAPGANALSACEL 441
ALV+R + V+ VL A L++V + GAGVD++D+ +A +GV V A ANA + E
Sbjct: 55 ALVLRGSKPVSAAVLRAAPALRIVAKNGAGVDSVDMEAARTQGVAVAVAQAANAPAVAEH 114
Query: 442 TCTLMLVLARHVVQL 486
LML L R + QL
Sbjct: 115 ALALMLALVRQLPQL 129
>UniRef50_Q5QUE2 Cluster: Erythronate-4-phosphate dehydrogenase;
n=2; Idiomarina|Rep: Erythronate-4-phosphate
dehydrogenase - Idiomarina loihiensis
Length = 381
Score = 58.4 bits (135), Expect = 2e-07
Identities = 34/96 (35%), Positives = 58/96 (60%), Gaps = 1/96 (1%)
Frame = +1
Query: 172 AELLNAYGIATTTKAKISKEELLMEIPNHDALVVRSATQVTKEVLDAGVKLKVVGRAGAG 351
++LL+ G + +I ++LL E DAL+VRS TQV + +L+ +LK V A G
Sbjct: 13 SDLLSGAGTLSYFSERIPPQKLLAEA---DALLVRSVTQVDEVLLEQAPELKFVASATIG 69
Query: 352 VDNIDVXSAGKKGVGVINAPGANALSACE-LTCTLM 456
++I++ + ++G+G +APGANA S E + C ++
Sbjct: 70 TEHINLQALEERGIGFAHAPGANAQSVGEYVLCAVL 105
>UniRef50_UPI000050F9E4 Cluster: COG0111: Phosphoglycerate
dehydrogenase and related dehydrogenases; n=1;
Brevibacterium linens BL2|Rep: COG0111: Phosphoglycerate
dehydrogenase and related dehydrogenases -
Brevibacterium linens BL2
Length = 314
Score = 58.0 bits (134), Expect = 3e-07
Identities = 26/69 (37%), Positives = 40/69 (57%)
Frame = +1
Query: 271 VRSATQVTKEVLDAGVKLKVVGRAGAGVDNIDVXSAGKKGVGVINAPGANALSACELTCT 450
+ ++ V +++L LKV+ RAG G DN+D+ +A + G+ V N PG N + EL
Sbjct: 54 IAASEPVARDMLATSPMLKVIARAGVGYDNVDIDAAAELGIRVCNTPGVNHHAVAELALA 113
Query: 451 LMLVLARHV 477
LML AR +
Sbjct: 114 LMLACARRL 122
>UniRef50_Q8CPW2 Cluster: Glycerate dehydrogenase; n=4;
Staphylococcus|Rep: Glycerate dehydrogenase -
Staphylococcus epidermidis (strain ATCC 12228)
Length = 323
Score = 57.6 bits (133), Expect = 4e-07
Identities = 30/88 (34%), Positives = 46/88 (52%)
Frame = +1
Query: 220 ISKEELLMEIPNHDALVVRSATQVTKEVLDAGVKLKVVGRAGAGVDNIDVXSAGKKGVGV 399
+S+E L + + A V+ + + +EV +LKV+ G DNID+ A K GV V
Sbjct: 34 MSRESFLANVEDATACVITLSEHIDEEVFLRAQQLKVIANMAVGFDNIDISLAKKHGVVV 93
Query: 400 INAPGANALSACELTCTLMLVLARHVVQ 483
N P + EL TLML +AR +++
Sbjct: 94 TNTPHVLTETTAELGFTLMLTVARRIIE 121
>UniRef50_Q3SK87 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase; n=4; Proteobacteria|Rep: D-isomer
specific 2-hydroxyacid dehydrogenase - Thiobacillus
denitrificans (strain ATCC 25259)
Length = 391
Score = 57.6 bits (133), Expect = 4e-07
Identities = 36/107 (33%), Positives = 61/107 (57%), Gaps = 1/107 (0%)
Frame = +1
Query: 163 AKCAELLNAYGIATTTKAKISKEELLM-EIPNHDALVVRSATQVTKEVLDAGVKLKVVGR 339
A+ ++L I+ A++ + ++ ++ + DA++VRSA E+ + +GR
Sbjct: 2 AEARKILTLNAISARGLARLPEHYVVGGDLADPDAILVRSANMHEMEI---PTSVCAIGR 58
Query: 340 AGAGVDNIDVXSAGKKGVGVINAPGANALSACELTCTLMLVLARHVV 480
AGAG +NI V ++G+ V NAPGANA + EL ML+ AR++V
Sbjct: 59 AGAGTNNIPVKKMSERGLPVFNAPGANANAVKELVIAGMLMGARNLV 105
Score = 44.8 bits (101), Expect = 0.003
Identities = 24/82 (29%), Positives = 38/82 (46%), Gaps = 2/82 (2%)
Frame = +3
Query: 525 YTGSELAGXXLXILGLGRVGXXVATXMYAFXMNIIGFQPFRVC*SVRPVPLHXXGAGGXF 704
+ G EL G L ++GLG +G +A MN++G+ P + +P A
Sbjct: 132 FAGMELPGRTLGVIGLGAIGSHIAEAAIRLGMNVVGYDPAITVDAAWRLPSQVKRAENVD 191
Query: 705 GPL--TDXITLHTPVIEXTXXL 764
L D +TLH P+++ T L
Sbjct: 192 DVLRTADFVTLHVPLLDATRNL 213
>UniRef50_Q4AIL7 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase, catalytic region:D- isomer specific
2-hydroxyacid dehydrogenase, NAD-binding precursor; n=1;
Chlorobium phaeobacteroides BS1|Rep: D-isomer specific
2-hydroxyacid dehydrogenase, catalytic region:D- isomer
specific 2-hydroxyacid dehydrogenase, NAD-binding
precursor - Chlorobium phaeobacteroides BS1
Length = 312
Score = 57.6 bits (133), Expect = 4e-07
Identities = 31/111 (27%), Positives = 53/111 (47%)
Frame = +1
Query: 133 KSVLIVDGVGAKCAELLNAYGIATTTKAKISKEELLMEIPNHDALVVRSATQVTKEVLDA 312
+ VL +D LL G + +++ L + +V+RS ++ E L +
Sbjct: 4 RKVLFIDSAHPSLTLLLQELGFTCDYFPEYKRDDYLKIASQYLGVVIRSKIKIDAEFLSS 63
Query: 313 GVKLKVVGRAGAGVDNIDVXSAGKKGVGVINAPGANALSACELTCTLMLVL 465
+L+ + R GAG++NID+ SA K V +NAP N + E ++L L
Sbjct: 64 ATQLRFIARVGAGMENIDIQSADKHQVVCLNAPEGNRDAVAEQAVGMILTL 114
>UniRef50_Q18XF4 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase, NAD-binding; n=2; Desulfitobacterium
hafniense|Rep: D-isomer specific 2-hydroxyacid
dehydrogenase, NAD-binding - Desulfitobacterium
hafniense (strain DCB-2)
Length = 320
Score = 57.6 bits (133), Expect = 4e-07
Identities = 29/65 (44%), Positives = 41/65 (63%)
Frame = +1
Query: 286 QVTKEVLDAGVKLKVVGRAGAGVDNIDVXSAGKKGVGVINAPGANALSACELTCTLMLVL 465
+V E L+A LK++ + G GVD+ID+ +A +G+ V NAPG NA S +L ML L
Sbjct: 61 KVYAEDLEAAPNLKLIIKHGTGVDSIDLKAAAARGITVANAPGTNANSVADLAFGFMLSL 120
Query: 466 ARHVV 480
AR +V
Sbjct: 121 ARQIV 125
Score = 33.9 bits (74), Expect = 5.3
Identities = 14/35 (40%), Positives = 21/35 (60%)
Frame = +3
Query: 531 GSELAGXXLXILGLGRVGXXVATXMYAFXMNIIGF 635
G ++ G L +LGLG++G V F MNI+G+
Sbjct: 141 GKDVYGKTLGVLGLGQIGKGVIRRASGFDMNILGY 175
>UniRef50_A4WXD4 Cluster: Dimethylmenaquinone methyltransferase;
n=1; Rhodobacter sphaeroides ATCC 17025|Rep:
Dimethylmenaquinone methyltransferase - Rhodobacter
sphaeroides ATCC 17025
Length = 334
Score = 57.6 bits (133), Expect = 4e-07
Identities = 29/79 (36%), Positives = 49/79 (62%)
Frame = +1
Query: 259 DALVVRSATQVTKEVLDAGVKLKVVGRAGAGVDNIDVXSAGKKGVGVINAPGANALSACE 438
DA++VR ++T EV+ A LKV+ + G GVDNID+ +A +G+ V+ + G+N+ + E
Sbjct: 58 DAMMVRQG-RITDEVIGASPGLKVIVKHGVGVDNIDLAAAEARGIPVLRSMGSNSRAVAE 116
Query: 439 LTCTLMLVLARHVVQLHCA 495
L L+L + + L+ A
Sbjct: 117 HAIALALMLVKEIQPLNAA 135
>UniRef50_A4AN91 Cluster: Predicted dehydrogenase; n=14;
Bacteroidetes|Rep: Predicted dehydrogenase -
Flavobacteriales bacterium HTCC2170
Length = 337
Score = 57.6 bits (133), Expect = 4e-07
Identities = 30/81 (37%), Positives = 45/81 (55%)
Frame = +1
Query: 223 SKEELLMEIPNHDALVVRSATQVTKEVLDAGVKLKVVGRAGAGVDNIDVXSAGKKGVGVI 402
SKE++ I +D + +RS + KE + LK +GR GAG++NIDV A KK + +
Sbjct: 56 SKEQIEHRIGEYDGITIRSRFTIDKEFIKKAKNLKFIGRVGAGLENIDVAYAKKKNIFLA 115
Query: 403 NAPGANALSACELTCTLMLVL 465
AP N + E T ++L L
Sbjct: 116 AAPEGNRNAVGEHTLGMLLSL 136
>UniRef50_Q27SN5 Cluster: Beta xylosidase-like protein; n=1;
Acanthamoeba castellanii|Rep: Beta xylosidase-like
protein - Acanthamoeba castellanii (Amoeba)
Length = 222
Score = 57.6 bits (133), Expect = 4e-07
Identities = 27/92 (29%), Positives = 50/92 (54%)
Frame = +1
Query: 208 TKAKISKEELLMEIPNHDALVVRSATQVTKEVLDAGVKLKVVGRAGAGVDNIDVXSAGKK 387
T+ + +EE+L ++ + DA++ + E++ G KLKV+ GAG D +DV +A ++
Sbjct: 7 TEDYMPREEVLHKVTDVDAIICHGKDKADAELVAKGSKLKVISNFGAGYDTVDVKAATER 66
Query: 388 GVGVINAPGANALSACELTCTLMLVLARHVVQ 483
+ V N PGA + ++ L+L R +
Sbjct: 67 NIWVCNTPGAVTNATADVALYLLLAACRRATE 98
>UniRef50_Q0RXQ1 Cluster: Probable phosphoglycerate dehydrogenase;
n=1; Rhodococcus sp. RHA1|Rep: Probable phosphoglycerate
dehydrogenase - Rhodococcus sp. (strain RHA1)
Length = 163
Score = 57.2 bits (132), Expect = 5e-07
Identities = 36/80 (45%), Positives = 46/80 (57%)
Frame = +1
Query: 235 LLMEIPNHDALVVRSATQVTKEVLDAGVKLKVVGRAGAGVDNIDVXSAGKKGVGVINAPG 414
L+ P+ DAL+V VT +VL A LKV+ R G GVD+IDV +A + GV V N P
Sbjct: 14 LIARCPHADALIVW-VQPVTADVLAALPHLKVISRLGTGVDSIDVPAANRHGVVVTNVPD 72
Query: 415 ANALSACELTCTLMLVLARH 474
AN+ T T+ L LA H
Sbjct: 73 ANSEEVA--THTMGLALAAH 90
>UniRef50_Q82U25 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase; n=3; Nitrosomonadaceae|Rep: D-isomer
specific 2-hydroxyacid dehydrogenase - Nitrosomonas
europaea
Length = 311
Score = 56.8 bits (131), Expect = 7e-07
Identities = 27/87 (31%), Positives = 49/87 (56%)
Frame = +1
Query: 217 KISKEELLMEIPNHDALVVRSATQVTKEVLDAGVKLKVVGRAGAGVDNIDVXSAGKKGVG 396
K++++E++ + N ++ +T+ VL + L+V+ R G G+DN+D+ +A + +
Sbjct: 37 KLTEDEIITLLGNDTVALLAGVEPLTEHVLTSASALRVIARCGTGMDNVDLEAARRLNIQ 96
Query: 397 VINAPGANALSACELTCTLMLVLARHV 477
V N P A A + ELT LML R +
Sbjct: 97 VSNTPEAPAQAVAELTLGLMLDCLRQI 123
>UniRef50_Q44NM9 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase, catalytic region:D- isomer specific
2-hydroxyacid dehydrogenase, NAD-binding; n=1;
Chlorobium limicola DSM 245|Rep: D-isomer specific
2-hydroxyacid dehydrogenase, catalytic region:D- isomer
specific 2-hydroxyacid dehydrogenase, NAD-binding -
Chlorobium limicola DSM 245
Length = 305
Score = 56.8 bits (131), Expect = 7e-07
Identities = 30/102 (29%), Positives = 49/102 (48%)
Frame = +1
Query: 184 NAYGIATTTKAKISKEELLMEIPNHDALVVRSATQVTKEVLDAGVKLKVVGRAGAGVDNI 363
N Y + + E+ ++EI +V + ++V+D L+ + R G G+D++
Sbjct: 25 NGYEVINNPFGRKLTEDEVIEIAKECVGIVAGVEPLNQKVMDNLPNLRCISRVGVGMDSV 84
Query: 364 DVXSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVQLH 489
D+ A +KG+ V N P S ELT + L L R V Q H
Sbjct: 85 DLDYAKQKGIVVTNTPDGPTRSVAELTIAMTLALLRKVPQAH 126
>UniRef50_Q01W77 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase, NAD-binding; n=1; Solibacter usitatus
Ellin6076|Rep: D-isomer specific 2-hydroxyacid
dehydrogenase, NAD-binding - Solibacter usitatus (strain
Ellin6076)
Length = 312
Score = 56.8 bits (131), Expect = 7e-07
Identities = 29/78 (37%), Positives = 45/78 (57%)
Frame = +1
Query: 262 ALVVRSATQVTKEVLDAGVKLKVVGRAGAGVDNIDVXSAGKKGVGVINAPGANALSACEL 441
AL +RS+++ T+ V A KL++V G G D++D+ +A + GV V N PG A S E
Sbjct: 52 ALNIRSSSRFTERVFAACPKLRMVSIWGTGTDHVDLAAAARHGVTVANTPGVAARSIAEH 111
Query: 442 TCTLMLVLARHVVQLHCA 495
T L+ +AR + + A
Sbjct: 112 TLALLFAVARQIPHMDAA 129
>UniRef50_A7HM61 Cluster: Glyoxylate reductase; n=1;
Fervidobacterium nodosum Rt17-B1|Rep: Glyoxylate
reductase - Fervidobacterium nodosum Rt17-B1
Length = 317
Score = 56.8 bits (131), Expect = 7e-07
Identities = 26/88 (29%), Positives = 49/88 (55%)
Frame = +1
Query: 220 ISKEELLMEIPNHDALVVRSATQVTKEVLDAGVKLKVVGRAGAGVDNIDVXSAGKKGVGV 399
+SKEE++ DA+V + + KE + + K K++ G +NID+ +A ++G+ V
Sbjct: 32 LSKEEMIKRAEYADAIVTQLRDPIDKEFIYSLKKAKIIANYAVGYNNIDIEAAKERGIYV 91
Query: 400 INAPGANALSACELTCTLMLVLARHVVQ 483
N PG + ++ L+L +AR +V+
Sbjct: 92 TNTPGVLTEATADIAFALILAVARRIVE 119
Score = 41.1 bits (92), Expect = 0.035
Identities = 24/81 (29%), Positives = 39/81 (48%)
Frame = +3
Query: 522 LYTGSELAGXXLXILGLGRVGXXVATXMYAFXMNIIGFQPFRVC*SVRPVPLHXXGAGGX 701
L+ G +L G L ++G+GR+G VA F MNI+ + R+ +
Sbjct: 136 LFLGYDLYGKTLGVIGMGRIGQAVARRALGFGMNIVYYNRNRLPEEIEKQYNAKYVNIDE 195
Query: 702 FGPLTDXITLHTPVIEXTXXL 764
++D I+LHTP+ + T L
Sbjct: 196 LVEISDYISLHTPLTKETYHL 216
>UniRef50_A7AAD2 Cluster: Putative uncharacterized protein; n=1;
Parabacteroides merdae ATCC 43184|Rep: Putative
uncharacterized protein - Parabacteroides merdae ATCC
43184
Length = 320
Score = 56.8 bits (131), Expect = 7e-07
Identities = 34/103 (33%), Positives = 48/103 (46%)
Frame = +1
Query: 175 ELLNAYGIATTTKAKISKEELLMEIPNHDALVVRSATQVTKEVLDAGVKLKVVGRAGAGV 354
EL + Y + + EE+L IP +D L V KE++D KLK+V G
Sbjct: 17 ELESKYEVTFPEGRDFTYEEVLEMIPEYDVLCSMFDFPVNKELIDHASKLKMVANYAVGY 76
Query: 355 DNIDVXSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVQ 483
+NIDV +KG+ V N P L LML +AR + +
Sbjct: 77 NNIDVAYCLEKGITVANTPDPVTAPTANLALGLMLDVARRITE 119
>UniRef50_Q72KT6 Cluster: Glycerate dehydrogenase/glyoxylate
reductase; n=2; Thermus thermophilus|Rep: Glycerate
dehydrogenase/glyoxylate reductase - Thermus
thermophilus (strain HB27 / ATCC BAA-163 / DSM 7039)
Length = 338
Score = 56.4 bits (130), Expect = 9e-07
Identities = 28/88 (31%), Positives = 48/88 (54%)
Frame = +1
Query: 220 ISKEELLMEIPNHDALVVRSATQVTKEVLDAGVKLKVVGRAGAGVDNIDVXSAGKKGVGV 399
+ K ELL + L+ ++ EV+D LKV+ GVD++D+ +A ++G+ V
Sbjct: 59 LPKAELLKRVEGAVGLIPTVEDRIDAEVMDRAKGLKVIACYSVGVDHVDLEAARERGIRV 118
Query: 400 INAPGANALSACELTCTLMLVLARHVVQ 483
+ PG + +LT L+L +AR VV+
Sbjct: 119 THTPGVLTEATADLTLALLLAVARRVVE 146
Score = 33.9 bits (74), Expect = 5.3
Identities = 23/81 (28%), Positives = 36/81 (44%)
Frame = +3
Query: 522 LYTGSELAGXXLXILGLGRVGXXVATXMYAFXMNIIGFQPFRVC*SVRPVPLHXXGAGGX 701
L G +L G L ++G+GR+G VA AF M ++ + +P+P
Sbjct: 163 LLLGLDLQGLTLGLVGMGRIGQAVAKRALAFGMRVVYHAR-----TPKPLPYPFLSLEEL 217
Query: 702 FGPLTDXITLHTPVIEXTXXL 764
D ++LHTP+ T L
Sbjct: 218 LKE-ADVVSLHTPLTPETHRL 237
>UniRef50_Q6W1I8 Cluster: D-3-phosphoglycerate dehydrogenase; n=1;
Rhizobium sp. NGR234|Rep: D-3-phosphoglycerate
dehydrogenase - Rhizobium sp. (strain NGR234)
Length = 327
Score = 56.4 bits (130), Expect = 9e-07
Identities = 33/84 (39%), Positives = 47/84 (55%)
Frame = +1
Query: 229 EELLMEIPNHDALVVRSATQVTKEVLDAGVKLKVVGRAGAGVDNIDVXSAGKKGVGVINA 408
+EL + + DA +V S T+EVL LKV+ R G G D+ID +A + GVG+
Sbjct: 41 DELATLLEDCDAAIV-STDPFTREVLAGDRNLKVIARVGVGTDSIDHDAAKEFGVGISVT 99
Query: 409 PGANALSACELTCTLMLVLARHVV 480
PG NA + + T ++L L R VV
Sbjct: 100 PGMNAETVADQTLAMILGLMRRVV 123
>UniRef50_A3Y4H8 Cluster: Erythronate-4-phosphate dehydrogenase;
n=1; Vibrio sp. MED222|Rep: Erythronate-4-phosphate
dehydrogenase - Vibrio sp. MED222
Length = 254
Score = 56.4 bits (130), Expect = 9e-07
Identities = 27/71 (38%), Positives = 43/71 (60%)
Frame = +1
Query: 259 DALVVRSATQVTKEVLDAGVKLKVVGRAGAGVDNIDVXSAGKKGVGVINAPGANALSACE 438
DAL++RS T+V + ++ KLK VG A AG+D++D ++G+ APG N + E
Sbjct: 39 DALMIRSVTKVNESLISKANKLKFVGTATAGMDHVDQELMKERGIFFTAAPGCNKVGVAE 98
Query: 439 LTCTLMLVLAR 471
+ M+VLA+
Sbjct: 99 YAFSAMMVLAQ 109
>UniRef50_A1HM37 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase, NAD-binding; n=3; cellular organisms|Rep:
D-isomer specific 2-hydroxyacid dehydrogenase,
NAD-binding - Thermosinus carboxydivorans Nor1
Length = 365
Score = 56.4 bits (130), Expect = 9e-07
Identities = 30/92 (32%), Positives = 53/92 (57%), Gaps = 1/92 (1%)
Frame = +1
Query: 217 KISKEELLMEIPNHDA-LVVRSATQVTKEVLDAGVKLKVVGRAGAGVDNIDVXSAGKKGV 393
+I + + L++ DA L+ ++ +V DA KL++VG + AG++N++V A K+G+
Sbjct: 60 EIEEVDALIQSEGKDAELLAGLFVPISSKVFDAMPKLRIVGVSRAGLENVNVKEATKRGI 119
Query: 394 GVINAPGANALSACELTCTLMLVLARHVVQLH 489
V N G NA + + T LML R++ + H
Sbjct: 120 LVFNIEGRNAEAVSDFTVGLMLAECRNIARAH 151
>UniRef50_A0JVX0 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase, NAD-binding; n=1; Arthrobacter sp.
FB24|Rep: D-isomer specific 2-hydroxyacid dehydrogenase,
NAD-binding - Arthrobacter sp. (strain FB24)
Length = 319
Score = 56.4 bits (130), Expect = 9e-07
Identities = 26/64 (40%), Positives = 42/64 (65%)
Frame = +1
Query: 286 QVTKEVLDAGVKLKVVGRAGAGVDNIDVXSAGKKGVGVINAPGANALSACELTCTLMLVL 465
+++ +VL+ +LK + R G GVD+IDV +A + G+ V+ APGAN+ ELT L+L
Sbjct: 72 RLSGQVLEDLTRLKAISRNGVGVDSIDVEAAERLGINVLTAPGANSQGVAELTIALILAG 131
Query: 466 ARHV 477
+R +
Sbjct: 132 SRSI 135
Score = 37.5 bits (83), Expect = 0.43
Identities = 21/70 (30%), Positives = 33/70 (47%)
Frame = +3
Query: 531 GSELAGXXLXILGLGRVGXXVATXMYAFXMNIIGFQPFRVC*SVRPVPLHXXGAGGXFGP 710
G+E++G L ++G G++G VAT M +I F + V S P P
Sbjct: 152 GNEVSGKVLGLIGCGQIGRRVATMALGLGMKVIAFDEYPVT-SFAPSPDFSWAPRERVLS 210
Query: 711 LTDXITLHTP 740
+ ++LHTP
Sbjct: 211 SSHVVSLHTP 220
>UniRef50_Q5KE95 Cluster: Phosphoglycerate dehydrogenase; n=2;
Filobasidiella neoformans|Rep: Phosphoglycerate
dehydrogenase - Cryptococcus neoformans (Filobasidiella
neoformans)
Length = 316
Score = 56.4 bits (130), Expect = 9e-07
Identities = 29/73 (39%), Positives = 42/73 (57%)
Frame = +1
Query: 268 VVRSATQVTKEVLDAGVKLKVVGRAGAGVDNIDVXSAGKKGVGVINAPGANALSACELTC 447
V+ A +T+E+LD KL + G G D+ID+ +KGV ++N PG N+ ELT
Sbjct: 83 VICRANLITREMLDKEGKLMGLAIVGVGYDSIDIEGCKEKGVTLMNCPGENSQVVAELTL 142
Query: 448 TLMLVLARHVVQL 486
+L L L R V +L
Sbjct: 143 SLTLALLRRVPEL 155
>UniRef50_Q6LNU2 Cluster: Erythronate-4-phosphate dehydrogenase;
n=16; Gammaproteobacteria|Rep: Erythronate-4-phosphate
dehydrogenase - Photobacterium profundum (Photobacterium
sp. (strain SS9))
Length = 391
Score = 56.4 bits (130), Expect = 9e-07
Identities = 31/110 (28%), Positives = 56/110 (50%)
Frame = +1
Query: 142 LIVDGVGAKCAELLNAYGIATTTKAKISKEELLMEIPNHDALVVRSATQVTKEVLDAGVK 321
+++D AEL G T + + L++I DAL++RS T+V ++ K
Sbjct: 3 ILIDENMPYAAELFGQLGEVVTKPGRTLSADDLIDI---DALMIRSVTKVNHNLISKANK 59
Query: 322 LKVVGRAGAGVDNIDVXSAGKKGVGVINAPGANALSACELTCTLMLVLAR 471
L+ VG A AG D++D ++G+ +APG N + E + ++V+ +
Sbjct: 60 LQFVGTATAGQDHVDQALLAERGITFTSAPGCNKVGVAEYVLSALMVIGQ 109
>UniRef50_UPI000023EBBC Cluster: hypothetical protein FG00146.1; n=1;
Gibberella zeae PH-1|Rep: hypothetical protein FG00146.1
- Gibberella zeae PH-1
Length = 1068
Score = 56.0 bits (129), Expect = 1e-06
Identities = 27/76 (35%), Positives = 46/76 (60%)
Frame = +1
Query: 250 PNHDALVVRSATQVTKEVLDAGVKLKVVGRAGAGVDNIDVXSAGKKGVGVINAPGANALS 429
P+ A++++ +T++ L + +L+V+G+ G G+D IDV + + V V N PG NA +
Sbjct: 790 PHATAILIKDY-YITEDDLASAPQLRVIGKQGVGLDKIDVEACKRHNVKVCNTPGVNASA 848
Query: 430 ACELTCTLMLVLARHV 477
E+T L L +AR V
Sbjct: 849 VAEMTLCLALTVAREV 864
>UniRef50_Q5FUW5 Cluster: D-3-phosphoglycerate dehydrogenase; n=55;
Bacteria|Rep: D-3-phosphoglycerate dehydrogenase -
Gluconobacter oxydans (Gluconobacter suboxydans)
Length = 416
Score = 56.0 bits (129), Expect = 1e-06
Identities = 35/115 (30%), Positives = 60/115 (52%), Gaps = 2/115 (1%)
Frame = +1
Query: 139 VLIVDGVGAKCAELLNAYGIATTTKAKISKE-ELLMEIPNHDALV-VRSATQVTKEVLDA 312
+L+++G+ A A G T+ K + E + L E +V +RS TQ+T+EVL+
Sbjct: 14 ILLLEGIHESAAAHFAAEGYTEVTRVKGALEGDALKEALQGVHMVGIRSRTQLTREVLEG 73
Query: 313 GVKLKVVGRAGAGVDNIDVXSAGKKGVGVINAPGANALSACELTCTLMLVLARHV 477
+L +G G + +D+ +A G+ V NAP +N S EL +++L R +
Sbjct: 74 ADRLMAIGCFCIGTNQVDLNAARMLGIPVFNAPFSNTRSVAELVMGEIVMLLRRI 128
>UniRef50_Q21A61 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase, NAD-binding; n=1; Rhodopseudomonas
palustris BisB18|Rep: D-isomer specific 2-hydroxyacid
dehydrogenase, NAD-binding - Rhodopseudomonas palustris
(strain BisB18)
Length = 321
Score = 56.0 bits (129), Expect = 1e-06
Identities = 30/73 (41%), Positives = 44/73 (60%)
Frame = +1
Query: 259 DALVVRSATQVTKEVLDAGVKLKVVGRAGAGVDNIDVXSAGKKGVGVINAPGANALSACE 438
DA++VR ++ +++ A LKVV + GAG ++ID+ +A GV V+ A GANA S E
Sbjct: 49 DAIIVRLVERIDADLMKASPNLKVVAKHGAGTNDIDLAAAKALGVPVLAAVGANAHSVAE 108
Query: 439 LTCTLMLVLARHV 477
LML L + V
Sbjct: 109 HAFMLMLALIKDV 121
Score = 36.7 bits (81), Expect = 0.76
Identities = 21/80 (26%), Positives = 33/80 (41%)
Frame = +3
Query: 525 YTGSELAGXXLXILGLGRVGXXVATXMYAFXMNIIGFQPFRVC*SVRPVPLHXXGAGGXF 704
Y G EL G L ++G+G +G +A + M I + PF + P
Sbjct: 138 YRGRELRGRVLGLVGIGMIGRALAAMVQPIGMTTIAYDPFAPAAAFGPHARRVDSLDELL 197
Query: 705 GPLTDXITLHTPVIEXTXXL 764
+D ++LH P+ T L
Sbjct: 198 AQ-SDVVSLHCPLTPQTQNL 216
>UniRef50_P40054 Cluster: D-3-phosphoglycerate dehydrogenase 1;
n=35; Eukaryota|Rep: D-3-phosphoglycerate dehydrogenase
1 - Saccharomyces cerevisiae (Baker's yeast)
Length = 469
Score = 56.0 bits (129), Expect = 1e-06
Identities = 33/118 (27%), Positives = 61/118 (51%), Gaps = 1/118 (0%)
Frame = +1
Query: 127 DIKSVLIVDGVGAKCAELLNAYGIATTT-KAKISKEELLMEIPNHDALVVRSATQVTKEV 303
D+K +L+++ V + G K+ + +EEL+ +I + A+ +RS T++T V
Sbjct: 58 DMK-ILLLENVNQTAITIFEEQGYQVEFYKSSLPEEELIEKIKDVHAIGIRSKTRLTSNV 116
Query: 304 LDAGVKLKVVGRAGAGVDNIDVXSAGKKGVGVINAPGANALSACELTCTLMLVLARHV 477
L L +G G + +D+ A +G+ V N+P +N+ S EL ++ LAR +
Sbjct: 117 LQHAKNLVCIGCFCIGTNQVDLDYATSRGIAVFNSPFSNSRSVAELVIAEIISLARQL 174
>UniRef50_UPI0000383A41 Cluster: COG1052: Lactate dehydrogenase and
related dehydrogenases; n=1; Magnetospirillum
magnetotacticum MS-1|Rep: COG1052: Lactate dehydrogenase
and related dehydrogenases - Magnetospirillum
magnetotacticum MS-1
Length = 167
Score = 55.6 bits (128), Expect = 2e-06
Identities = 30/91 (32%), Positives = 49/91 (53%), Gaps = 1/91 (1%)
Frame = +1
Query: 214 AKISKEELLMEIPNHDALVVRSATQVTKEVL-DAGVKLKVVGRAGAGVDNIDVXSAGKKG 390
A +S+E L I D LV ++ +L AG L+++ G GVD+IDV +A ++G
Sbjct: 60 APLSQEALAAAIREADVLVPTVTDEINAGLLAQAGPNLRLIANFGNGVDHIDVGAALERG 119
Query: 391 VGVINAPGANALSACELTCTLMLVLARHVVQ 483
+ V N PG ++T L+L +AR + +
Sbjct: 120 ITVTNTPGVLTEDTADMTMALILAVARRIAE 150
>UniRef50_A7BQE7 Cluster: D-3-phosphoglycerate dehydrogenase; n=1;
Beggiatoa sp. PS|Rep: D-3-phosphoglycerate dehydrogenase
- Beggiatoa sp. PS
Length = 302
Score = 55.6 bits (128), Expect = 2e-06
Identities = 30/85 (35%), Positives = 47/85 (55%)
Frame = +1
Query: 223 SKEELLMEIPNHDALVVRSATQVTKEVLDAGVKLKVVGRAGAGVDNIDVXSAGKKGVGVI 402
+KE LL I + D ++++S ++ KE + A LK+V AG G+D+I + K+G+
Sbjct: 30 NKERLLEVIEDKDVVILKSRIELDKEAIFAAKHLKLVVMAGIGLDHICLDELKKRGIAWF 89
Query: 403 NAPGANALSACELTCTLMLVLARHV 477
N P +A EL L L LAR +
Sbjct: 90 NIPDLSARGVAELVLGLTLSLARKI 114
>UniRef50_A3PPC6 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase, NAD-binding; n=4; Rhodobacteraceae|Rep:
D-isomer specific 2-hydroxyacid dehydrogenase,
NAD-binding - Rhodobacter sphaeroides (strain ATCC 17029
/ ATH 2.4.9)
Length = 331
Score = 55.6 bits (128), Expect = 2e-06
Identities = 39/112 (34%), Positives = 52/112 (46%)
Frame = +1
Query: 142 LIVDGVGAKCAELLNAYGIATTTKAKISKEELLMEIPNHDALVVRSATQVTKEVLDAGVK 321
LIV + L A GIA + + DA++ R A + AG +
Sbjct: 4 LIVQPIHEAGLAALRAAGIAPILCPAPDMATVARHMAGIDAVITRDAG-LDAAAFAAGDR 62
Query: 322 LKVVGRAGAGVDNIDVXSAGKKGVGVINAPGANALSACELTCTLMLVLARHV 477
L+ V GAG D +D +A +KGV V N PGANA S EL L L +AR +
Sbjct: 63 LRAVVVHGAGHDPVDKEAAARKGVVVANTPGANARSVAELAVGLALAVARRI 114
>UniRef50_Q5PCV8 Cluster: Erythronate-4-phosphate dehydrogenase;
n=44; Gammaproteobacteria|Rep: Erythronate-4-phosphate
dehydrogenase - Salmonella paratyphi-a
Length = 378
Score = 55.6 bits (128), Expect = 2e-06
Identities = 29/75 (38%), Positives = 46/75 (61%)
Frame = +1
Query: 244 EIPNHDALVVRSATQVTKEVLDAGVKLKVVGRAGAGVDNIDVXSAGKKGVGVINAPGANA 423
E+ + DAL+VRS T+V + +L +G + VG A AG D++D + G+G APG NA
Sbjct: 34 ELNHADALMVRSVTKVNESLL-SGTPINFVGTATAGTDHVDEAWLKQAGIGFSAAPGCNA 92
Query: 424 LSACELTCTLMLVLA 468
++ E + +L+LA
Sbjct: 93 IAVVEYVFSALLMLA 107
>UniRef50_A1SW94 Cluster: Erythronate-4-phosphate dehydrogenase;
n=2; Psychromonas|Rep: Erythronate-4-phosphate
dehydrogenase - Psychromonas ingrahamii (strain 37)
Length = 383
Score = 55.6 bits (128), Expect = 2e-06
Identities = 29/70 (41%), Positives = 41/70 (58%)
Frame = +1
Query: 259 DALVVRSATQVTKEVLDAGVKLKVVGRAGAGVDNIDVXSAGKKGVGVINAPGANALSACE 438
D L+VRS T+V +++L KLK VG A G D+ID +G+ +APG N +S E
Sbjct: 39 DVLLVRSITEVNEKLLSLNKKLKFVGTATIGTDHIDQTYLKNRGIVFSSAPGCNKVSVAE 98
Query: 439 LTCTLMLVLA 468
+ +LVLA
Sbjct: 99 YILSSLLVLA 108
>UniRef50_Q8FPW0 Cluster: Putative uncharacterized protein; n=1;
Corynebacterium efficiens|Rep: Putative uncharacterized
protein - Corynebacterium efficiens
Length = 161
Score = 55.2 bits (127), Expect = 2e-06
Identities = 38/82 (46%), Positives = 41/82 (50%)
Frame = -1
Query: 473 WRARTNINVQVSSHALSALAPGALITPTPFLPAEXTSMLSTPAPARPTTFSFTPASNTSL 294
WRA S A L GAL T TP A S LS P PARPT F A+ TS
Sbjct: 37 WRAVDRSRETACSQAEWMLEVGALATMTPASVAAGMSTLSRPTPARPTIFRLGAAAMTSA 96
Query: 293 VT*VAERTTRASWLGISIRSSS 228
T VAERT RAS ++ SSS
Sbjct: 97 STLVAERTRRAS-ASLTASSSS 117
>UniRef50_Q6A5K9 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase, putative D-3- phosphoglycerate
dehydrogenase; n=1; Propionibacterium acnes|Rep:
D-isomer specific 2-hydroxyacid dehydrogenase, putative
D-3- phosphoglycerate dehydrogenase - Propionibacterium
acnes
Length = 321
Score = 55.2 bits (127), Expect = 2e-06
Identities = 30/95 (31%), Positives = 52/95 (54%)
Frame = +1
Query: 220 ISKEELLMEIPNHDALVVRSATQVTKEVLDAGVKLKVVGRAGAGVDNIDVXSAGKKGVGV 399
+ ++EL +I DA++ + + E++ G LKV+G+ AG +NID+ +A + GV V
Sbjct: 31 MDRQELSRQIATADAILTSLSDPLDAEMIGQGKNLKVIGQCAAGFNNIDLDAAKQAGVVV 90
Query: 400 INAPGANALSACELTCTLMLVLARHVVQLHCAEXW 504
+ PG + +L TL+L + R + AE W
Sbjct: 91 TSTPGVLHEATADLAFTLLLEVTRRTGE---AERW 122
>UniRef50_Q5WLJ2 Cluster: D-3-phosphoglycerate dehydrogenase; n=2;
Bacillus|Rep: D-3-phosphoglycerate dehydrogenase -
Bacillus clausii (strain KSM-K16)
Length = 316
Score = 55.2 bits (127), Expect = 2e-06
Identities = 31/86 (36%), Positives = 47/86 (54%)
Frame = +1
Query: 220 ISKEELLMEIPNHDALVVRSATQVTKEVLDAGVKLKVVGRAGAGVDNIDVXSAGKKGVGV 399
IS+ ++E A +V + ++ VL LK++ + G GVDNIDV +A K GV V
Sbjct: 35 ISQSAFVLEARGAQAAIV-AFNEIHDAVLAQLPDLKIIAKHGVGVDNIDVDAAKKHGVTV 93
Query: 400 INAPGANALSACELTCTLMLVLARHV 477
N P AN + + +L+L LAR +
Sbjct: 94 TNVPNANKHAVADFAFSLLLSLARQI 119
>UniRef50_A4ETV8 Cluster: Putative uncharacterized protein; n=6;
Alphaproteobacteria|Rep: Putative uncharacterized
protein - Roseobacter sp. SK209-2-6
Length = 166
Score = 55.2 bits (127), Expect = 2e-06
Identities = 35/83 (42%), Positives = 40/83 (48%)
Frame = -1
Query: 473 WRARTNINVQVSSHALSALAPGALITPTPFLPAEXTSMLSTPAPARPTTFSFTPASNTSL 294
WRA NI S + L G IT TP L A SMLS P PAR T + +
Sbjct: 36 WRATANIIAMACSAVVIILPNGVFITITPRLEAASLSMLSVPMPARAMTLRLSALARIFS 95
Query: 293 VT*VAERTTRASWLGISIRSSSL 225
VT VAER R S+ I+ S SL
Sbjct: 96 VTLVAERMARPSYWPITSASLSL 118
>UniRef50_A0ZEB8 Cluster: Predicted dehydrogenase; n=6;
Cyanobacteria|Rep: Predicted dehydrogenase - Nodularia
spumigena CCY 9414
Length = 341
Score = 55.2 bits (127), Expect = 2e-06
Identities = 29/89 (32%), Positives = 47/89 (52%)
Frame = +1
Query: 223 SKEELLMEIPNHDALVVRSATQVTKEVLDAGVKLKVVGRAGAGVDNIDVXSAGKKGVGVI 402
+K E+ I + VR T++ + + KLKV+ +G G D ID+ A K GV V+
Sbjct: 46 TKNEINQAIQEASGVFVRYPTKLDAQAIGLAKKLKVISTSGFGTDAIDISVATKHGVVVV 105
Query: 403 NAPGANALSACELTCTLMLVLARHVVQLH 489
N PG + + E T ++L LA+ + L+
Sbjct: 106 NNPGLSTTAVAEHTICMILALAKKLTFLN 134
>UniRef50_Q5KQ73 Cluster: D-3-phosphoglycerate dehydrogenase,
putative; n=3; Filobasidiella neoformans|Rep:
D-3-phosphoglycerate dehydrogenase, putative -
Cryptococcus neoformans (Filobasidiella neoformans)
Length = 594
Score = 55.2 bits (127), Expect = 2e-06
Identities = 26/53 (49%), Positives = 34/53 (64%)
Frame = +1
Query: 313 GVKLKVVGRAGAGVDNIDVXSAGKKGVGVINAPGANALSACELTCTLMLVLAR 471
G KLK + + G GVD ID+ +A K G+ V+N PG NA + EL +ML LAR
Sbjct: 96 GGKLKYISKQGTGVDKIDIVNAKKLGIPVMNTPGVNAQAVAELAFGMMLSLAR 148
>UniRef50_Q5AUK0 Cluster: Putative uncharacterized protein; n=1;
Emericella nidulans|Rep: Putative uncharacterized
protein - Emericella nidulans (Aspergillus nidulans)
Length = 251
Score = 55.2 bits (127), Expect = 2e-06
Identities = 30/81 (37%), Positives = 45/81 (55%), Gaps = 1/81 (1%)
Frame = +1
Query: 256 HDALV-VRSATQVTKEVLDAGVKLKVVGRAGAGVDNIDVXSAGKKGVGVINAPGANALSA 432
HDA + + + +T+EVL A +L+ V GV+ +D+ + +KGV VIN PGAN +
Sbjct: 53 HDATIAITTLVPITREVLQACPRLQCVIIMATGVEWVDIPAFQEKGVKVINCPGANVSTV 112
Query: 433 CELTCTLMLVLARHVVQLHCA 495
E L R +V+LH A
Sbjct: 113 AEHALALYFASRRKIVELHDA 133
>UniRef50_Q0CUD5 Cluster: Putative uncharacterized protein; n=1;
Aspergillus terreus NIH2624|Rep: Putative
uncharacterized protein - Aspergillus terreus (strain
NIH 2624)
Length = 743
Score = 55.2 bits (127), Expect = 2e-06
Identities = 28/75 (37%), Positives = 45/75 (60%)
Frame = +1
Query: 253 NHDALVVRSATQVTKEVLDAGVKLKVVGRAGAGVDNIDVXSAGKKGVGVINAPGANALSA 432
N AL++RS+ +T E + + L +G+ G G++ ID + K+G+ ++N PGANA
Sbjct: 476 NARALLIRSS-YLTAEDIASCPNLVAIGKHGVGIEKIDQDACVKRGIKILNTPGANARDV 534
Query: 433 CELTCTLMLVLARHV 477
EL TL L +AR +
Sbjct: 535 AELVVTLALSVARGI 549
>UniRef50_Q8YEC6 Cluster: Gluconate 2-dehydrogenase; n=72;
Alphaproteobacteria|Rep: Gluconate 2-dehydrogenase -
Brucella melitensis
Length = 360
Score = 54.8 bits (126), Expect = 3e-06
Identities = 28/90 (31%), Positives = 49/90 (54%), Gaps = 1/90 (1%)
Frame = +1
Query: 217 KISKEELLMEIPNHDALVVRSATQVTKEVLD-AGVKLKVVGRAGAGVDNIDVXSAGKKGV 393
++S+ E++ + D LV + V++ AG LK++ G GVDNIDV +A ++G+
Sbjct: 63 RMSQPEIIAALKEADVLVPCITDVIDAAVIEQAGPNLKLIANFGNGVDNIDVAAAARRGI 122
Query: 394 GVINAPGANALSACELTCTLMLVLARHVVQ 483
V N P ++T L+L + R +V+
Sbjct: 123 TVTNTPNVLTEDTADMTLALLLSVPRRLVE 152
>UniRef50_Q8UJZ6 Cluster: Phosphoglycerate dehydrogenase; n=3;
Alphaproteobacteria|Rep: Phosphoglycerate dehydrogenase
- Agrobacterium tumefaciens (strain C58 / ATCC 33970)
Length = 354
Score = 54.8 bits (126), Expect = 3e-06
Identities = 28/74 (37%), Positives = 45/74 (60%)
Frame = +1
Query: 265 LVVRSATQVTKEVLDAGVKLKVVGRAGAGVDNIDVXSAGKKGVGVINAPGANALSACELT 444
+VVR + ++ + A L+V+ + G GVDNIDV +A ++ + V+ A GANALS E
Sbjct: 76 VVVRMG-RFSEAAIKAAPSLRVLSKHGVGVDNIDVDAASRREIPVVVAAGANALSVAEHA 134
Query: 445 CTLMLVLARHVVQL 486
TL+ + + +V L
Sbjct: 135 ITLLFAVVKRIVPL 148
Score = 35.9 bits (79), Expect = 1.3
Identities = 20/83 (24%), Positives = 35/83 (42%)
Frame = +3
Query: 516 RALYTGSELAGXXLXILGLGRVGXXVATXMYAFXMNIIGFQPFRVC*SVRPVPLHXXGAG 695
+A Y+G ELAG + ++G G + A F + + + PF + +H
Sbjct: 159 KAGYSGKELAGMIIGLVGFGAIARQTAVFARGFGLKVQAYDPFTDETAFVEAGVHRVADV 218
Query: 696 GXFGPLTDXITLHTPVIEXTXXL 764
+D ++LH P+ T L
Sbjct: 219 DDLISSSDILSLHCPLTPDTRNL 241
>UniRef50_Q30V14 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase family protein; n=3; Desulfovibrio|Rep:
D-isomer specific 2-hydroxyacid dehydrogenase family
protein - Desulfovibrio desulfuricans (strain G20)
Length = 305
Score = 54.8 bits (126), Expect = 3e-06
Identities = 29/77 (37%), Positives = 44/77 (57%), Gaps = 1/77 (1%)
Frame = +1
Query: 259 DALVVRSATQ-VTKEVLDAGVKLKVVGRAGAGVDNIDVXSAGKKGVGVINAPGANALSAC 435
D + V + T+ +T V+DA LKV+ R G G+DN+D+ +A +G+ V N P +
Sbjct: 48 DCVAVAAGTEPLTARVMDALPGLKVISRCGTGMDNVDMEAARARGIAVRNTPDGPTQAVA 107
Query: 436 ELTCTLMLVLARHVVQL 486
ELT L L L R V ++
Sbjct: 108 ELTLGLALDLMRQVSRM 124
>UniRef50_A6UCB8 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase NAD-binding; n=2; Sinorhizobium|Rep:
D-isomer specific 2-hydroxyacid dehydrogenase
NAD-binding - Sinorhizobium medicae WSM419
Length = 310
Score = 54.8 bits (126), Expect = 3e-06
Identities = 23/63 (36%), Positives = 39/63 (61%)
Frame = +1
Query: 289 VTKEVLDAGVKLKVVGRAGAGVDNIDVXSAGKKGVGVINAPGANALSACELTCTLMLVLA 468
V+ +V+ A L+ + R G G+DN+ + ++G+G++ A GANA+ EL+ LML
Sbjct: 60 VSDKVIAAADSLRAISRNGTGIDNLPLPLLKERGIGILKAEGANAVGVAELSVGLMLAAL 119
Query: 469 RHV 477
RH+
Sbjct: 120 RHI 122
>UniRef50_Q6A895 Cluster: D-3-phosphoglycerate dehydrogenase; n=2;
Actinomycetales|Rep: D-3-phosphoglycerate dehydrogenase
- Propionibacterium acnes
Length = 417
Score = 54.4 bits (125), Expect = 4e-06
Identities = 32/118 (27%), Positives = 60/118 (50%), Gaps = 2/118 (1%)
Frame = +1
Query: 130 IKSVLIVDGVGAKCAELLNAYGIATTTKAK-ISKEELLMEIPNHDALVVRSATQVTKEVL 306
+ L+++ + + L G ++ + +++L+ + D L +RS T+VT+ V+
Sbjct: 21 VMKALLLENIHDEAVRTLKKAGYEVERVSEALDEDDLISALDGVDLLGIRSRTRVTRRVV 80
Query: 307 DA-GVKLKVVGRAGAGVDNIDVXSAGKKGVGVINAPGANALSACELTCTLMLVLARHV 477
+A G KL VG G + +D+ + + GV NAP +N S EL ++ LAR +
Sbjct: 81 EACGDKLHAVGAFCIGTNQMDLDALAEAGVPAFNAPYSNTRSVVELVMAEIIALARRL 138
>UniRef50_A1G3C5 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase, NAD-binding; n=1; Salinispora arenicola
CNS205|Rep: D-isomer specific 2-hydroxyacid
dehydrogenase, NAD-binding - Salinispora arenicola
CNS205
Length = 345
Score = 54.4 bits (125), Expect = 4e-06
Identities = 28/69 (40%), Positives = 39/69 (56%)
Frame = +1
Query: 265 LVVRSATQVTKEVLDAGVKLKVVGRAGAGVDNIDVXSAGKKGVGVINAPGANALSACELT 444
L VR Q+T +VLDA +L V +G GVDNID+ +A + GV V N PG E
Sbjct: 47 LAVRYPAQITADVLDAAPQLLAVLSSGRGVDNIDIPAASRAGVVVANNPGLGGKPVSEHA 106
Query: 445 CTLMLVLAR 471
L++++ R
Sbjct: 107 LGLLIMITR 115
>UniRef50_Q5FKH9 Cluster: Glyoxylate reductase; n=1; Lactobacillus
acidophilus|Rep: Glyoxylate reductase - Lactobacillus
acidophilus
Length = 321
Score = 54.0 bits (124), Expect = 5e-06
Identities = 27/84 (32%), Positives = 45/84 (53%)
Frame = +1
Query: 226 KEELLMEIPNHDALVVRSATQVTKEVLDAGVKLKVVGRAGAGVDNIDVXSAGKKGVGVIN 405
++ +L I +D ++V KE++DA LKV+ G G D+ID+ A +KG+ V N
Sbjct: 39 RQWVLKNIAKYDGVIVAKMI-FDKEIIDAAKNLKVISTYGVGFDHIDIDYAREKGIVVTN 97
Query: 406 APGANALSACELTCTLMLVLARHV 477
P + EL T+++ AR +
Sbjct: 98 CPNSVLRPTAELALTMIMASARRI 121
>UniRef50_Q2BM60 Cluster: Erythronate-4-phosphate dehydrogenase;
n=1; Neptuniibacter caesariensis|Rep:
Erythronate-4-phosphate dehydrogenase - Neptuniibacter
caesariensis
Length = 376
Score = 54.0 bits (124), Expect = 5e-06
Identities = 33/97 (34%), Positives = 50/97 (51%)
Frame = +1
Query: 178 LLNAYGIATTTKAKISKEELLMEIPNHDALVVRSATQVTKEVLDAGVKLKVVGRAGAGVD 357
+ + +G T + K E ++ + D L+VRS TQV +LD+ +K VG A G D
Sbjct: 20 MFSGFGKVTRAPGRNLKAE---DVADADVLLVRSITQVNAALLDSS-SVKFVGTATIGTD 75
Query: 358 NIDVXSAGKKGVGVINAPGANALSACELTCTLMLVLA 468
+ID + G+G NAPG NA + E + + LA
Sbjct: 76 HIDQNYLVQNGIGFSNAPGCNADAVVEYVLSCIYALA 112
>UniRef50_A6VXM3 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase catalytic region; n=2; Marinomonas|Rep:
D-isomer specific 2-hydroxyacid dehydrogenase catalytic
region - Marinomonas sp. MWYL1
Length = 380
Score = 54.0 bits (124), Expect = 5e-06
Identities = 27/60 (45%), Positives = 39/60 (65%)
Frame = +1
Query: 244 EIPNHDALVVRSATQVTKEVLDAGVKLKVVGRAGAGVDNIDVXSAGKKGVGVINAPGANA 423
++ D L+VRS T+VTKE+L+ G ++ VG A GVD+ID+ K +G +APG NA
Sbjct: 34 QVREADVLLVRSVTKVTKELLE-GSSVRFVGSATIGVDHIDLDYLSKANIGFSSAPGCNA 92
>UniRef50_A3JX80 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase, NAD-binding protein; n=1; Sagittula
stellata E-37|Rep: D-isomer specific 2-hydroxyacid
dehydrogenase, NAD-binding protein - Sagittula stellata
E-37
Length = 320
Score = 54.0 bits (124), Expect = 5e-06
Identities = 30/100 (30%), Positives = 50/100 (50%)
Frame = +1
Query: 196 IATTTKAKISKEELLMEIPNHDALVVRSATQVTKEVLDAGVKLKVVGRAGAGVDNIDVXS 375
I TT +IS++ I DAL++R+ +T +D +LK+V R G G D +DV +
Sbjct: 24 ITTTYIDEISEDSYTPHIAGADALLIRTQA-LTSPTIDRADRLKIVSRHGVGYDAVDVAA 82
Query: 376 AGKKGVGVINAPGANALSACELTCTLMLVLARHVVQLHCA 495
+G+ + AN+ S E C L+L + ++ A
Sbjct: 83 LNARGIALAVCGDANSTSVAEHACMLILAAFKRALRADVA 122
Score = 37.5 bits (83), Expect = 0.43
Identities = 18/45 (40%), Positives = 22/45 (48%)
Frame = +3
Query: 510 GXRALYTGSELAGXXLXILGLGRVGXXVATXMYAFXMNIIGFQPF 644
G R ++ G L ILG GR+G AT M F MNI P+
Sbjct: 129 GWRNQLESQDIRGRNLLILGFGRIGQHTATMMSGFGMNIRAHDPY 173
>UniRef50_A0QQ27 Cluster: Glyoxylate reductase; n=4;
Mycobacterium|Rep: Glyoxylate reductase - Mycobacterium
smegmatis (strain ATCC 700084 / mc(2)155)
Length = 322
Score = 54.0 bits (124), Expect = 5e-06
Identities = 29/66 (43%), Positives = 41/66 (62%)
Frame = +1
Query: 289 VTKEVLDAGVKLKVVGRAGAGVDNIDVXSAGKKGVGVINAPGANALSACELTCTLMLVLA 468
+T + L+ +L++V + GAGV+ IDV +A + G+ V N PGANA S E T LML
Sbjct: 61 ITGDDLNRAPRLRLVHKLGAGVNTIDVETATQLGILVANMPGANAPSVAEGTVLLMLAAL 120
Query: 469 RHVVQL 486
R + QL
Sbjct: 121 RRLPQL 126
>UniRef50_A5N6P2 Cluster: GyaR; n=1; Clostridium kluyveri DSM
555|Rep: GyaR - Clostridium kluyveri DSM 555
Length = 329
Score = 53.6 bits (123), Expect = 6e-06
Identities = 27/86 (31%), Positives = 49/86 (56%)
Frame = +1
Query: 223 SKEELLMEIPNHDALVVRSATQVTKEVLDAGVKLKVVGRAGAGVDNIDVXSAGKKGVGVI 402
S+ E+L + N +A+++ + ++ ++++ LK++ G + ID +A ++G+ V
Sbjct: 35 SQTEILDQAKNVNAIIIDAIAKLPEKIIVQMPNLKIIQSEGVAYNGIDCRAAKQRGIYVC 94
Query: 403 NAPGANALSACELTCTLMLVLARHVV 480
N GANA S E T LML L R +V
Sbjct: 95 NCKGANASSVAEQTILLMLALLRSMV 120
>UniRef50_A4EAR0 Cluster: Putative uncharacterized protein; n=1;
Collinsella aerofaciens ATCC 25986|Rep: Putative
uncharacterized protein - Collinsella aerofaciens ATCC
25986
Length = 387
Score = 53.6 bits (123), Expect = 6e-06
Identities = 31/75 (41%), Positives = 47/75 (62%)
Frame = +1
Query: 259 DALVVRSATQVTKEVLDAGVKLKVVGRAGAGVDNIDVXSAGKKGVGVINAPGANALSACE 438
DA+++RS T + L G++ + R GAGV+NI V KKGV V N+PGAN+ + E
Sbjct: 32 DAILMRS-TDLHGYELPEGIR--AIARCGAGVNNIPVEEYAKKGVVVFNSPGANSNAVKE 88
Query: 439 LTCTLMLVLARHVVQ 483
L ++++ +R VVQ
Sbjct: 89 LVLGMLVLSSRGVVQ 103
Score = 37.1 bits (82), Expect = 0.57
Identities = 15/40 (37%), Positives = 22/40 (55%)
Frame = +3
Query: 525 YTGSELAGXXLXILGLGRVGXXVATXMYAFXMNIIGFQPF 644
+ G EL G + ++GLG VG VA M++ G+ PF
Sbjct: 128 FVGRELKGKRIGVIGLGNVGSKVANACVDLGMDVYGYDPF 167
>UniRef50_A1U1I8 Cluster: Erythronate-4-phosphate dehydrogenase;
n=4; Gammaproteobacteria|Rep: Erythronate-4-phosphate
dehydrogenase - Marinobacter aquaeolei (strain ATCC
700491 / DSM 11845 / VT8)(Marinobacter
hydrocarbonoclasticus (strain DSM 11845))
Length = 384
Score = 53.6 bits (123), Expect = 6e-06
Identities = 26/75 (34%), Positives = 47/75 (62%)
Frame = +1
Query: 244 EIPNHDALVVRSATQVTKEVLDAGVKLKVVGRAGAGVDNIDVXSAGKKGVGVINAPGANA 423
++ + D L+VRS T+V +++L+ G +++ VG A G D+ID ++G+G APG NA
Sbjct: 34 QVKDADILLVRSVTRVDRQLLE-GTRVRFVGTATIGTDHIDQTWLQEQGIGFAAAPGCNA 92
Query: 424 LSACELTCTLMLVLA 468
+S E +++ + A
Sbjct: 93 VSVAEYVLSVLSLYA 107
>UniRef50_UPI000023F60F Cluster: hypothetical protein FG08018.1;
n=1; Gibberella zeae PH-1|Rep: hypothetical protein
FG08018.1 - Gibberella zeae PH-1
Length = 901
Score = 53.2 bits (122), Expect = 8e-06
Identities = 25/71 (35%), Positives = 39/71 (54%)
Frame = +1
Query: 265 LVVRSATQVTKEVLDAGVKLKVVGRAGAGVDNIDVXSAGKKGVGVINAPGANALSACELT 444
L+VRS+ ++++ L +G+ G G+D IDV + +G+ + N PG NA + EL
Sbjct: 61 LLVRSSRLTAQDIISCP-NLVAIGKQGVGLDKIDVDACASRGIKIFNTPGVNARAVAELV 119
Query: 445 CTLMLVLARHV 477
TL AR V
Sbjct: 120 LTLATASARQV 130
>UniRef50_Q8GQX5 Cluster: 2-oxo-4-phenylbutanoate reductase; n=2;
Leuconostocaceae|Rep: 2-oxo-4-phenylbutanoate reductase
- Oenococcus oeni (Leuconostoc oenos)
Length = 306
Score = 53.2 bits (122), Expect = 8e-06
Identities = 34/115 (29%), Positives = 55/115 (47%), Gaps = 1/115 (0%)
Frame = +1
Query: 130 IKSVLIVDGVGAKCAELLNAYGIATTTKAKISKEELLMEIPNHDAL-VVRSATQVTKEVL 306
+K VL+ DG+ + L + I + + + ++ L N D ++ V K +L
Sbjct: 1 MKKVLVFDGIAQVAIDYLKSNHIEVISNQQKNDDDFLA---NQDLNGIILMMHPVDKHIL 57
Query: 307 DAGVKLKVVGRAGAGVDNIDVXSAGKKGVGVINAPGANALSACELTCTLMLVLAR 471
LK+V R G G DN+++ A ++ V V N PGANA + E ML+ R
Sbjct: 58 SQLPDLKIVARYGVGYDNVNLEDASQQHVIVTNTPGANATAVAETALMHMLMSGR 112
>UniRef50_Q03YV3 Cluster: Lactate dehydrogenase related enzyme; n=1;
Leuconostoc mesenteroides subsp. mesenteroides ATCC
8293|Rep: Lactate dehydrogenase related enzyme -
Leuconostoc mesenteroides subsp. mesenteroides (strain
ATCC 8293 /NCDO 523)
Length = 314
Score = 53.2 bits (122), Expect = 8e-06
Identities = 30/117 (25%), Positives = 60/117 (51%)
Frame = +1
Query: 133 KSVLIVDGVGAKCAELLNAYGIATTTKAKISKEELLMEIPNHDALVVRSATQVTKEVLDA 312
K V + D + A ++L G+ + E++ E A+++ + +++DA
Sbjct: 3 KQVFLPDDIPAVGKKILEEAGLEVVVGSGRDHEKMKAEGVEASAVLI-GTQKFDADIMDA 61
Query: 313 GVKLKVVGRAGAGVDNIDVXSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVQ 483
LKV+ R G G D +DV +A ++G+ V+N P A + S E + +L +++++ Q
Sbjct: 62 MPNLKVIARNGVGYDAVDVDAATQRGIYVVNTPKALSGSVAETAVSELLAISKNLYQ 118
Score = 38.7 bits (86), Expect = 0.19
Identities = 16/43 (37%), Positives = 24/43 (55%)
Frame = +3
Query: 516 RALYTGSELAGXXLXILGLGRVGXXVATXMYAFXMNIIGFQPF 644
R + G ++ G + ILG GR+G VA + F + +I F PF
Sbjct: 131 RKAHPGRDIEGKTVGILGFGRIGQQVAKKLSGFDVKVIAFDPF 173
>UniRef50_Q3IF36 Cluster: Erythronate-4-phosphate dehydrogenase;
n=3; Alteromonadales|Rep: Erythronate-4-phosphate
dehydrogenase - Pseudoalteromonas haloplanktis (strain
TAC 125)
Length = 373
Score = 53.2 bits (122), Expect = 8e-06
Identities = 27/71 (38%), Positives = 38/71 (53%)
Frame = +1
Query: 259 DALVVRSATQVTKEVLDAGVKLKVVGRAGAGVDNIDVXSAGKKGVGVINAPGANALSACE 438
D L+ RS TQV E+L KL VG A GVD+ID K + +APG NA++ E
Sbjct: 39 DVLLTRSVTQVNNELLAHANKLSFVGTATIGVDHIDTQLLNDKNIAFSSAPGCNAIAVAE 98
Query: 439 LTCTLMLVLAR 471
+ + L++
Sbjct: 99 YVISSLYALSQ 109
>UniRef50_UPI00015B49ED Cluster: PREDICTED: similar to putative
glyoxylate reductase/hydroxypyruvate reductase; n=1;
Nasonia vitripennis|Rep: PREDICTED: similar to putative
glyoxylate reductase/hydroxypyruvate reductase - Nasonia
vitripennis
Length = 699
Score = 52.8 bits (121), Expect = 1e-05
Identities = 29/93 (31%), Positives = 49/93 (52%), Gaps = 1/93 (1%)
Frame = +1
Query: 220 ISKEELLMEIPNHDALVVRSATQVTKEVLDA-GVKLKVVGRAGAGVDNIDVXSAGKKGVG 396
I K EL+ I DA+ ++ +EVL A G KLKV+ GVD++D+ + + +
Sbjct: 410 IPKPELIKRIKEADAIFCLLTDKIDEEVLSAAGSKLKVIATMSVGVDHLDLKAIKSRNIP 469
Query: 397 VINAPGANALSACELTCTLMLVLARHVVQLHCA 495
+ PG + ELT L+L +R +++ + A
Sbjct: 470 IGYTPGVLTDATAELTMALLLATSRRLIEANRA 502
>UniRef50_Q88ZU6 Cluster: Phosphoglycerate dehydrogenase; n=2;
Lactobacillus|Rep: Phosphoglycerate dehydrogenase -
Lactobacillus plantarum
Length = 392
Score = 52.8 bits (121), Expect = 1e-05
Identities = 30/74 (40%), Positives = 45/74 (60%)
Frame = +1
Query: 259 DALVVRSATQVTKEVLDAGVKLKVVGRAGAGVDNIDVXSAGKKGVGVINAPGANALSACE 438
DA ++RS T E L + LKV+ RAGAGV+NI + A G V N PG+NA + E
Sbjct: 31 DAYLIRSVNLHT-ETLPSS--LKVIVRAGAGVNNIPIDQATANGTAVFNTPGSNANAVKE 87
Query: 439 LTCTLMLVLARHVV 480
L L+++ +R+++
Sbjct: 88 LIIGLLIMASRNLI 101
Score = 41.9 bits (94), Expect = 0.020
Identities = 17/40 (42%), Positives = 24/40 (60%)
Frame = +3
Query: 525 YTGSELAGXXLXILGLGRVGXXVATXMYAFXMNIIGFQPF 644
+ G EL G L ++GLG VG VA + MN+IG+ P+
Sbjct: 126 FNGIELTGKTLAVIGLGHVGALVANAALSLGMNVIGYDPY 165
>UniRef50_A0UAW1 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase, NAD-binding; n=14; Burkholderiales|Rep:
D-isomer specific 2-hydroxyacid dehydrogenase,
NAD-binding - Burkholderia multivorans ATCC 17616
Length = 452
Score = 52.8 bits (121), Expect = 1e-05
Identities = 31/120 (25%), Positives = 59/120 (49%), Gaps = 2/120 (1%)
Frame = +1
Query: 133 KSVLIVDG--VGAKCAELLNAYGIATTTKAKISKEELLMEIPNHDALVVRSATQVTKEVL 306
K V++V + + E+L + + K + + + + + ++ ++ V+
Sbjct: 144 KPVVLVTAADLAPQALEMLAQFDVVFAGKQPTEDDIVALCVKHKPVAIIVRYGKINARVM 203
Query: 307 DAGVKLKVVGRAGAGVDNIDVXSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVQL 486
DA L+V+ + G+G+D ID +A +G+ V A GANA + E L+L A+ V QL
Sbjct: 204 DAAENLQVISKHGSGIDVIDQDAAAARGIAVRAAVGANAAAVAEHAWALILACAKSVPQL 263
Score = 37.9 bits (84), Expect = 0.33
Identities = 17/43 (39%), Positives = 24/43 (55%)
Frame = +3
Query: 516 RALYTGSELAGXXLXILGLGRVGXXVATXMYAFXMNIIGFQPF 644
+A + EL G L ++GLG +G VA AF M ++ F PF
Sbjct: 274 KATHKSVELDGRTLGLVGLGAIGRRVAAIGVAFGMKVLAFDPF 316
>UniRef50_Q2S0U3 Cluster: Erythronate-4-phosphate dehydrogenase;
n=1; Salinibacter ruber DSM 13855|Rep:
Erythronate-4-phosphate dehydrogenase - Salinibacter
ruber (strain DSM 13855)
Length = 392
Score = 52.8 bits (121), Expect = 1e-05
Identities = 32/96 (33%), Positives = 49/96 (51%)
Frame = +1
Query: 184 NAYGIATTTKAKISKEELLMEIPNHDALVVRSATQVTKEVLDAGVKLKVVGRAGAGVDNI 363
+A+G T + +E ++ D L+VRS T V +LD G L+ VG A G D++
Sbjct: 17 DAFGQFGTVRRMPGREMTTSDVAAADVLLVRSVTPVGPALLD-GTPLRFVGSATIGTDHV 75
Query: 364 DVXSAGKKGVGVINAPGANALSACELTCTLMLVLAR 471
D +G+ +APG+NA S + +L LAR
Sbjct: 76 DRDYLRAQGIPFAHAPGSNADSVADYVVAALLGLAR 111
>UniRef50_Q8Y3L1 Cluster: Lmo2824 protein; n=14; Bacillales|Rep:
Lmo2824 protein - Listeria monocytogenes
Length = 395
Score = 52.4 bits (120), Expect = 1e-05
Identities = 25/54 (46%), Positives = 35/54 (64%)
Frame = +1
Query: 322 LKVVGRAGAGVDNIDVXSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVQ 483
+K V RAGAGV+NI V + +KG+ V N PGANA + EL + V AR +++
Sbjct: 50 VKAVARAGAGVNNIPVENCSEKGIVVFNTPGANANAVKELVLASLFVSARPILE 103
Score = 43.6 bits (98), Expect = 0.007
Identities = 24/83 (28%), Positives = 41/83 (49%), Gaps = 2/83 (2%)
Frame = +3
Query: 525 YTGSELAGXXLXILGLGRVGXXVATXMYAFXMNIIGFQPFRVC*SVRPVPLHXXGAGGXF 704
+ G+ELAG L I+GLG +G VA + M+++G+ PF + + A
Sbjct: 128 FAGTELAGKKLGIIGLGAIGALVANDALSLGMDVVGYDPFVSVDTAWRISKEVERAMTIE 187
Query: 705 GPLT--DXITLHTPVIEXTXXLY 767
L D +T+H P+ + T ++
Sbjct: 188 EVLATCDYLTVHVPLTDKTRGMF 210
>UniRef50_Q63VJ5 Cluster: D-3-phosphoglycerate dehydrogenase; n=8;
Burkholderiaceae|Rep: D-3-phosphoglycerate dehydrogenase
- Burkholderia pseudomallei (Pseudomonas pseudomallei)
Length = 424
Score = 52.4 bits (120), Expect = 1e-05
Identities = 27/89 (30%), Positives = 44/89 (49%)
Frame = +1
Query: 211 KAKISKEELLMEIPNHDALVVRSATQVTKEVLDAGVKLKVVGRAGAGVDNIDVXSAGKKG 390
K ++ EL + H + +RSAT + ++ +DA L +G G +D+ +A G
Sbjct: 52 KGALAGAELRRALQQHQLIGIRSATHLLRDEIDAARHLLAIGCFCIGTSQVDLPAAAHHG 111
Query: 391 VGVINAPGANALSACELTCTLMLVLARHV 477
+ V NAP +N S EL ++L R V
Sbjct: 112 IPVFNAPFSNTRSVAELVIAEAILLLRRV 140
>UniRef50_A4SNU1 Cluster: Erythronate-4-phosphate dehydrogenase;
n=2; Aeromonas|Rep: Erythronate-4-phosphate
dehydrogenase - Aeromonas salmonicida (strain A449)
Length = 377
Score = 52.4 bits (120), Expect = 1e-05
Identities = 28/83 (33%), Positives = 46/83 (55%), Gaps = 1/83 (1%)
Frame = +1
Query: 241 MEIPNHDALVVRSATQVTKEVLDAGVKLKVVGRAGAGVDNIDVXSAGKKGVGVINAPGAN 420
+++ + D L+VRS T+V E+L +L+ VG A G D++D + + +APG N
Sbjct: 33 VDLQDADVLLVRSVTRVDAELLATSPRLRFVGTATIGTDHVDKALLAVRNIPFFSAPGCN 92
Query: 421 ALSACELTCTLMLVLA-RHVVQL 486
S + + +LVLA RH + L
Sbjct: 93 KYSVGDYVLSTLLVLAERHELNL 115
>UniRef50_Q82XE1 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase; n=5; Proteobacteria|Rep: D-isomer
specific 2-hydroxyacid dehydrogenase - Nitrosomonas
europaea
Length = 403
Score = 52.0 bits (119), Expect = 2e-05
Identities = 28/79 (35%), Positives = 45/79 (56%)
Frame = +1
Query: 244 EIPNHDALVVRSATQVTKEVLDAGVKLKVVGRAGAGVDNIDVXSAGKKGVGVINAPGANA 423
+I D ++VRS E+ ++ + +GRAGAG +NI V +G+ V N PGANA
Sbjct: 35 DITGPDVILVRSHNLHDMEIPESVI---AIGRAGAGTNNIPVNQMSARGIPVFNTPGANA 91
Query: 424 LSACELTCTLMLVLARHVV 480
+ EL ML+ +R+++
Sbjct: 92 NAVRELVLAGMLMASRNLI 110
>UniRef50_A5Z3X2 Cluster: Putative uncharacterized protein; n=1;
Eubacterium ventriosum ATCC 27560|Rep: Putative
uncharacterized protein - Eubacterium ventriosum ATCC
27560
Length = 387
Score = 52.0 bits (119), Expect = 2e-05
Identities = 31/74 (41%), Positives = 39/74 (52%)
Frame = +1
Query: 259 DALVVRSATQVTKEVLDAGVKLKVVGRAGAGVDNIDVXSAGKKGVGVINAPGANALSACE 438
D +VRSA LD L + RAGAGV+NI + KGV V N PGANA E
Sbjct: 32 DVALVRSAAM---HDLDLPESLLAIARAGAGVNNIPLDKCADKGVVVFNTPGANANGVKE 88
Query: 439 LTCTLMLVLARHVV 480
L ML+ +R ++
Sbjct: 89 LVLCGMLLASRDII 102
Score = 39.5 bits (88), Expect = 0.11
Identities = 22/79 (27%), Positives = 36/79 (45%), Gaps = 2/79 (2%)
Frame = +3
Query: 525 YTGSELAGXXLXILGLGRVGXXVATXMYAFXMNIIGFQPFRVC*SVRPV--PLHXXGAGG 698
+ G+E+ G L ++GLG +G VA + M + G PF + +H
Sbjct: 128 FAGNEIKGKKLGVIGLGAIGRLVANAAESMGMEVYGNDPFISVEGALSLKRDVHLVKTRE 187
Query: 699 XFGPLTDXITLHTPVIEXT 755
D IT+HTP+++ T
Sbjct: 188 EIFKECDFITVHTPLVDDT 206
>UniRef50_A5UPU9 Cluster: Glyoxylate reductase; n=12; Bacteria|Rep:
Glyoxylate reductase - Roseiflexus sp. RS-1
Length = 340
Score = 52.0 bits (119), Expect = 2e-05
Identities = 27/90 (30%), Positives = 46/90 (51%)
Frame = +1
Query: 220 ISKEELLMEIPNHDALVVRSATQVTKEVLDAGVKLKVVGRAGAGVDNIDVXSAGKKGVGV 399
+ +E LL + + D ++ +V E+L A +LKVV G DN+D+ + +GV +
Sbjct: 35 VPRETLLRAVADVDGILTLLTDRVDTELLAAAPRLKVVANMAVGYDNVDLPALTARGVLL 94
Query: 400 INAPGANALSACELTCTLMLVLARHVVQLH 489
N P + +L L+L +R VV+ H
Sbjct: 95 TNTPDVLTETTADLVWALILAASRRVVEGH 124
>UniRef50_A1UEI9 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase, NAD-binding; n=5; Mycobacterium|Rep:
D-isomer specific 2-hydroxyacid dehydrogenase,
NAD-binding - Mycobacterium sp. (strain KMS)
Length = 321
Score = 52.0 bits (119), Expect = 2e-05
Identities = 33/87 (37%), Positives = 44/87 (50%), Gaps = 1/87 (1%)
Frame = +1
Query: 223 SKEELLMEIPNHDALVVRSATQVTKEVLDA-GVKLKVVGRAGAGVDNIDVXSAGKKGVGV 399
+++EL A VV +V E+LDA G L+VV G DNIDV +A GV V
Sbjct: 38 TRDELAAGFTGACAAVVTLTERVDAEILDAAGDGLRVVANVAVGYDNIDVAAAHAAGVTV 97
Query: 400 INAPGANALSACELTCTLMLVLARHVV 480
N PG + + T L+L + R VV
Sbjct: 98 TNTPGVLDNATADHTFALILAVTRRVV 124
>UniRef50_Q1QXV7 Cluster: Erythronate-4-phosphate dehydrogenase;
n=1; Chromohalobacter salexigens DSM 3043|Rep:
Erythronate-4-phosphate dehydrogenase - Chromohalobacter
salexigens (strain DSM 3043 / ATCC BAA-138 / NCIMB13768)
Length = 383
Score = 52.0 bits (119), Expect = 2e-05
Identities = 27/74 (36%), Positives = 43/74 (58%)
Frame = +1
Query: 247 IPNHDALVVRSATQVTKEVLDAGVKLKVVGRAGAGVDNIDVXSAGKKGVGVINAPGANAL 426
+ D LVVRS T+V +L+ G +++ VG G D++D+ + G+G NAPG NA
Sbjct: 35 VREQDLLVVRSITRVDAALLE-GSRVRFVGTCTIGTDHVDLDYLREAGIGFANAPGCNAD 93
Query: 427 SACELTCTLMLVLA 468
S + + +L+LA
Sbjct: 94 SVVDYVLSSLLLLA 107
>UniRef50_Q81N95 Cluster: D-3-phosphoglycerate dehydrogenase,
putative; n=19; Bacteria|Rep: D-3-phosphoglycerate
dehydrogenase, putative - Bacillus anthracis
Length = 390
Score = 51.6 bits (118), Expect = 2e-05
Identities = 29/77 (37%), Positives = 46/77 (59%), Gaps = 1/77 (1%)
Frame = +1
Query: 253 NH-DALVVRSATQVTKEVLDAGVKLKVVGRAGAGVDNIDVXSAGKKGVGVINAPGANALS 429
NH D +++RS + +E LK + RAGAGV+NI V +KG+ V N PGANA +
Sbjct: 30 NHPDGILLRSYSLHQEEF---SKDLKAIARAGAGVNNIPVERCTEKGIVVFNTPGANANA 86
Query: 430 ACELTCTLMLVLARHVV 480
EL +++ +R+++
Sbjct: 87 VKELIIASLIMSSRNII 103
Score = 45.6 bits (103), Expect = 0.002
Identities = 25/79 (31%), Positives = 38/79 (48%), Gaps = 2/79 (2%)
Frame = +3
Query: 525 YTGSELAGXXLXILGLGRVGXXVATXMYAFXMNIIGFQPFRVC*SVRPVPLHXXGAGG-- 698
+ GSE+AG L ++GLG +G VA A M+++G+ P+ + + H A
Sbjct: 128 FVGSEIAGKRLGVIGLGAIGALVANDALALGMDVVGYDPYISVETAWRLSTHVQRAFSLD 187
Query: 699 XFGPLTDXITLHTPVIEXT 755
D ITLH P+ T
Sbjct: 188 EIFATCDYITLHIPLTNQT 206
>UniRef50_Q120S8 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase, NAD-binding; n=2; Proteobacteria|Rep:
D-isomer specific 2-hydroxyacid dehydrogenase,
NAD-binding - Polaromonas sp. (strain JS666 / ATCC
BAA-500)
Length = 325
Score = 51.6 bits (118), Expect = 2e-05
Identities = 29/86 (33%), Positives = 46/86 (53%)
Frame = +1
Query: 223 SKEELLMEIPNHDALVVRSATQVTKEVLDAGVKLKVVGRAGAGVDNIDVXSAGKKGVGVI 402
S+E ++ + D ++VR ++ V++ V+DA + K V R G GVDNID+ +A + + V
Sbjct: 45 SEEAAILAVRGADVVLVRESS-VSRRVIDAMDRCKAVIRYGIGVDNIDMAAAAARRIAVA 103
Query: 403 NAPGANALSACELTCTLMLVLARHVV 480
N P T L L + R VV
Sbjct: 104 NVPDYGTDEVSTQTVALALAVVRQVV 129
>UniRef50_A5URV2 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase, NAD-binding; n=1; Roseiflexus sp.
RS-1|Rep: D-isomer specific 2-hydroxyacid dehydrogenase,
NAD-binding - Roseiflexus sp. RS-1
Length = 323
Score = 51.6 bits (118), Expect = 2e-05
Identities = 26/57 (45%), Positives = 34/57 (59%)
Frame = +1
Query: 310 AGVKLKVVGRAGAGVDNIDVXSAGKKGVGVINAPGANALSACELTCTLMLVLARHVV 480
AG L+ + R G GVDNID+ +A K+G+ VIN P S E L+L LA+ VV
Sbjct: 65 AGDALRAICRPGIGVDNIDIAAATKRGILVINTPDGPTESTAEHAVALLLALAKQVV 121
>UniRef50_Q8MR05 Cluster: LD48009p; n=11; Coelomata|Rep: LD48009p -
Drosophila melanogaster (Fruit fly)
Length = 362
Score = 51.6 bits (118), Expect = 2e-05
Identities = 31/89 (34%), Positives = 44/89 (49%), Gaps = 1/89 (1%)
Frame = +1
Query: 220 ISKEELLMEIPNHDALVVRSATQVTKEVLDA-GVKLKVVGRAGAGVDNIDVXSAGKKGVG 396
+ + EL+ + DAL +V KEVLDA G +LK V G D+IDV K+G+
Sbjct: 74 VPRSELIRVVAGKDALYCALTDKVDKEVLDAAGPQLKCVATISVGYDHIDVEECRKRGIR 133
Query: 397 VINAPGANALSACELTCTLMLVLARHVVQ 483
V P + ELT L+L R + +
Sbjct: 134 VGFTPDVLTDATAELTLALLLATNRRLFE 162
>UniRef50_O50096 Cluster: Putative uncharacterized protein PH1388;
n=1; Pyrococcus horikoshii|Rep: Putative uncharacterized
protein PH1388 - Pyrococcus horikoshii
Length = 119
Score = 51.6 bits (118), Expect = 2e-05
Identities = 32/60 (53%), Positives = 32/60 (53%)
Frame = -1
Query: 467 ARTNINVQVSSHALSALAPGALITPTPFLPAEXTSMLSTPAPARPTTFSFTPASNTSLVT 288
A NIN SS L LA GAL T PF A TSMLS P PA T SF S T LVT
Sbjct: 34 ATENINPTASSATLLELAAGALTTSIPFSLAASTSMLSKPTPALAITLSFGALSITLLVT 93
>UniRef50_A4YFM2 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase, NAD-binding; n=1; Metallosphaera sedula
DSM 5348|Rep: D-isomer specific 2-hydroxyacid
dehydrogenase, NAD-binding - Metallosphaera sedula DSM
5348
Length = 324
Score = 51.6 bits (118), Expect = 2e-05
Identities = 34/126 (26%), Positives = 67/126 (53%), Gaps = 2/126 (1%)
Frame = +1
Query: 115 KMVVDIKSVLIVDGVGAKCAELLNAYGIATTTKAKISKEELLMEIPNHDALVVRSATQVT 294
K VV I S +IV+ + + LN+ +++++ + + A+V R A +++
Sbjct: 2 KPVVGIDSSVIVEELDQEKVRELNSLAEIVYFNPYAPEDQIVSLLRDAIAIVDRKA-KIS 60
Query: 295 KEVLDAGVKLKVVGRAGAGVDN--IDVXSAGKKGVGVINAPGANALSACELTCTLMLVLA 468
+++ LK++ R GAGVD +D+ +A ++ + + PG N+++ ELT L + L
Sbjct: 61 SKIIRELRNLKLIARTGAGVDETRVDLKAAKERDIIITYNPGGNSVAVAELTIMLAIALY 120
Query: 469 RHVVQL 486
R V+ L
Sbjct: 121 RKVIPL 126
>UniRef50_Q74CK1 Cluster: Glycerate dehydrogenase; n=12;
Bacteria|Rep: Glycerate dehydrogenase - Geobacter
sulfurreducens
Length = 327
Score = 51.2 bits (117), Expect = 3e-05
Identities = 28/82 (34%), Positives = 44/82 (53%)
Frame = +1
Query: 232 ELLMEIPNHDALVVRSATQVTKEVLDAGVKLKVVGRAGAGVDNIDVXSAGKKGVGVINAP 411
EL +E +V+ S ++ + L A KL+ + G +N+DV +AGK+G+ V N P
Sbjct: 40 ELRVERAKDADIVLTSKVKLDEATLAALPKLRYISMLATGYNNVDVEAAGKRGIPVANIP 99
Query: 412 GANALSACELTCTLMLVLARHV 477
+ S + T L+L LA HV
Sbjct: 100 AYSTESVVQTTFALLLELAVHV 121
>UniRef50_UPI00015BD3AA Cluster: UPI00015BD3AA related cluster; n=1;
unknown|Rep: UPI00015BD3AA UniRef100 entry - unknown
Length = 332
Score = 50.8 bits (116), Expect = 4e-05
Identities = 29/78 (37%), Positives = 43/78 (55%), Gaps = 1/78 (1%)
Frame = +1
Query: 241 MEIPNH-DALVVRSATQVTKEVLDAGVKLKVVGRAGAGVDNIDVXSAGKKGVGVINAPGA 417
+EIP+ + L V ++++K+V+D+ LK++ G D+IDV A KG+ V N P
Sbjct: 38 VEIPDDIEILSVFIYSKISKDVIDSLPDLKLIATRSTGFDHIDVAYANSKGITVCNVPSY 97
Query: 418 NALSACELTCTLMLVLAR 471
S E LML LAR
Sbjct: 98 GEESVSEYAIMLMLALAR 115
>UniRef50_Q8YK31 Cluster: Glycerate dehydrogenase; n=3;
Cyanobacteria|Rep: Glycerate dehydrogenase - Anabaena
sp. (strain PCC 7120)
Length = 332
Score = 50.8 bits (116), Expect = 4e-05
Identities = 33/117 (28%), Positives = 58/117 (49%), Gaps = 2/117 (1%)
Frame = +1
Query: 139 VLIVDGVGAKCAELL--NAYGIATTTKAKISKEELLMEIPNHDALVVRSATQVTKEVLDA 312
V+I + V + ELL + IA +K +S+EE+L + +AL+V + + L
Sbjct: 5 VVITNWVHPEVIELLKPSCEVIANPSKEALSREEILQRAKDAEALMVFMPDTIDEAFLRE 64
Query: 313 GVKLKVVGRAGAGVDNIDVXSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVQ 483
KLK++ A G DN DV + +G+ P + E+T L++ L R +++
Sbjct: 65 CPKLKIIAAALKGYDNFDVAACTHRGIWFTIVPSLLSAPTAEITIGLLIGLGRQMLE 121
>UniRef50_Q883D2 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase family protein; n=1; Pseudomonas syringae
pv. tomato|Rep: D-isomer specific 2-hydroxyacid
dehydrogenase family protein - Pseudomonas syringae pv.
tomato
Length = 313
Score = 50.8 bits (116), Expect = 4e-05
Identities = 32/87 (36%), Positives = 46/87 (52%), Gaps = 1/87 (1%)
Frame = +1
Query: 220 ISKEELLMEIPNHDALVVRSATQVTKEVLDAGVKLKVVGRAGAGVDN-IDVXSAGKKGVG 396
I KEEL+ + + DA ++ A +V +E L KLK + G G + ID+ +A G+
Sbjct: 34 IPKEELVRLLIDADAYILGGAERVAQEELVQAKKLKCISFVGTGAGSFIDLQAAEALGIA 93
Query: 397 VINAPGANALSACELTCTLMLVLARHV 477
V N PG A + E T LML L R +
Sbjct: 94 VTNTPGIAARAVAEHTLGLMLGLRRRL 120
>UniRef50_A6W4F1 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase NAD-binding; n=2; Actinomycetales|Rep:
D-isomer specific 2-hydroxyacid dehydrogenase
NAD-binding - Kineococcus radiotolerans SRS30216
Length = 326
Score = 50.8 bits (116), Expect = 4e-05
Identities = 29/73 (39%), Positives = 40/73 (54%)
Frame = +1
Query: 259 DALVVRSATQVTKEVLDAGVKLKVVGRAGAGVDNIDVXSAGKKGVGVINAPGANALSACE 438
DALVV+ A +V ++LDA ++ VGR G GVD +DV + +GV V N P S +
Sbjct: 46 DALVVQYA-RVDADLLDALPTVRAVGRYGVGVDTVDVDACTARGVAVCNVPDYGTESVSD 104
Query: 439 LTCTLMLVLARHV 477
L L AR +
Sbjct: 105 HAIALALAAARRI 117
>UniRef50_A6ULR7 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase NAD-binding; n=1; Sinorhizobium medicae
WSM419|Rep: D-isomer specific 2-hydroxyacid
dehydrogenase NAD-binding - Sinorhizobium medicae WSM419
Length = 328
Score = 50.8 bits (116), Expect = 4e-05
Identities = 31/90 (34%), Positives = 52/90 (57%)
Frame = +1
Query: 208 TKAKISKEELLMEIPNHDALVVRSATQVTKEVLDAGVKLKVVGRAGAGVDNIDVXSAGKK 387
T+A+++ E L P DA++ R+ + +++ L+V+ R G G +N+D+ SA ++
Sbjct: 34 TEAELA--ESLRSTP-FDAVISRTLA-LPAMMIETAPALRVISRHGVGYNNVDIESATRR 89
Query: 388 GVGVINAPGANALSACELTCTLMLVLARHV 477
GV V+ A GAN S EL L L +AR +
Sbjct: 90 GVPVLIADGANGKSVAELAVGLALSVARKI 119
>UniRef50_A3ZMM2 Cluster: Dehydrogenase; n=1; Blastopirellula marina
DSM 3645|Rep: Dehydrogenase - Blastopirellula marina DSM
3645
Length = 321
Score = 50.8 bits (116), Expect = 4e-05
Identities = 28/77 (36%), Positives = 40/77 (51%)
Frame = +1
Query: 259 DALVVRSATQVTKEVLDAGVKLKVVGRAGAGVDNIDVXSAGKKGVGVINAPGANALSACE 438
DA++ A VT +V+ A LK+V R G G+DNIDV ++ + V N P + E
Sbjct: 51 DAILTNWAN-VTAKVIAASPNLKIVARLGIGLDNIDVAYCTQQKIPVTNIPDYCVIEVAE 109
Query: 439 LTCTLMLVLARHVVQLH 489
T L+L AR + H
Sbjct: 110 HTLALLLACARKIAMYH 126
>UniRef50_O28495 Cluster: 2-hydroxyacid dehydrogenase, putative;
n=4; Archaea|Rep: 2-hydroxyacid dehydrogenase, putative
- Archaeoglobus fulgidus
Length = 323
Score = 50.8 bits (116), Expect = 4e-05
Identities = 25/67 (37%), Positives = 38/67 (56%)
Frame = +1
Query: 289 VTKEVLDAGVKLKVVGRAGAGVDNIDVXSAGKKGVGVINAPGANALSACELTCTLMLVLA 468
+T+E++ A K+K++ + G +NIDV +A K + V N G NALS E T L L
Sbjct: 60 ITEEMMRAMEKVKLIQQPSTGYNNIDVEAAKKLSITVANVGGVNALSVAEHTVMFALALL 119
Query: 469 RHVVQLH 489
R ++ H
Sbjct: 120 RRLIYAH 126
>UniRef50_Q0VQC3 Cluster: Erythronate-4-phosphate dehydrogenase;
n=2; Alcanivorax borkumensis SK2|Rep:
Erythronate-4-phosphate dehydrogenase - Alcanivorax
borkumensis (strain SK2 / ATCC 700651 / DSM 11573)
Length = 371
Score = 50.8 bits (116), Expect = 4e-05
Identities = 30/90 (33%), Positives = 49/90 (54%), Gaps = 1/90 (1%)
Frame = +1
Query: 199 ATTTKAKISKEELLME-IPNHDALVVRSATQVTKEVLDAGVKLKVVGRAGAGVDNIDVXS 375
A T ++ L E + + D L+VRS T+V + +L AG ++K VG A G D++D+
Sbjct: 17 AFATVERVDGRSLTREQLGDADVLLVRSVTRVDRALL-AGSQVKFVGSATIGTDHVDLAY 75
Query: 376 AGKKGVGVINAPGANALSACELTCTLMLVL 465
+ G+ +APG NA + E +L+L
Sbjct: 76 LSEAGIQFAHAPGCNARAVAEYVLQAVLLL 105
>UniRef50_Q896Z8 Cluster: 2-hydroxyacid dehydrogenase; n=4;
Clostridium|Rep: 2-hydroxyacid dehydrogenase -
Clostridium tetani
Length = 357
Score = 50.4 bits (115), Expect = 6e-05
Identities = 28/87 (32%), Positives = 49/87 (56%)
Frame = +1
Query: 229 EELLMEIPNHDALVVRSATQVTKEVLDAGVKLKVVGRAGAGVDNIDVXSAGKKGVGVINA 408
E L + D L++ + + KEV++A LK++ A G+D+I++ + K + V N+
Sbjct: 81 EVLKKRVETADVLILANMP-LKKEVIEAATNLKMISVAFTGIDHINMETCRKNNIMVCNS 139
Query: 409 PGANALSACELTCTLMLVLARHVVQLH 489
G + S ELT L+L L R++V L+
Sbjct: 140 AGYSTSSVVELTFGLILSLLRNIVPLN 166
>UniRef50_Q3DL54 Cluster: Glyoxylate reductase, NADH-dependent; n=9;
Streptococcus|Rep: Glyoxylate reductase, NADH-dependent
- Streptococcus agalactiae 515
Length = 318
Score = 50.4 bits (115), Expect = 6e-05
Identities = 28/119 (23%), Positives = 62/119 (52%), Gaps = 1/119 (0%)
Frame = +1
Query: 124 VDIKSVLIVDGVGAK-CAELLNAYGIATTTKAKISKEELLMEIPNHDALVVRSATQVTKE 300
+D K +L+ V + +L++ + + + S++ +L + +D ++ + KE
Sbjct: 1 MDKKKILVTGTVPKEGLRKLMDRFDVTYSEDRPFSRDYVLEHLSEYDGWLLMGQ-KGDKE 59
Query: 301 VLDAGVKLKVVGRAGAGVDNIDVXSAGKKGVGVINAPGANALSACELTCTLMLVLARHV 477
++DAG L+++ G D++D A +KG+ V N+P A + E+T L+L ++ +
Sbjct: 60 MIDAGENLQIISLNAVGFDHVDTAYAKEKGIIVSNSPQAVRVPTAEMTFALILAASKRL 118
Score = 33.5 bits (73), Expect = 7.1
Identities = 16/42 (38%), Positives = 22/42 (52%)
Frame = +3
Query: 525 YTGSELAGXXLXILGLGRVGXXVATXMYAFXMNIIGFQPFRV 650
Y G L G L I G+GR+G VA AF M ++ +R+
Sbjct: 138 YQGLTLQGSTLGIYGMGRIGLTVANFAKAFGMTVVYNDVYRL 179
>UniRef50_Q1WVK4 Cluster: D-3-phosphoglycerate dehydrogenase; n=1;
Lactobacillus salivarius subsp. salivarius UCC118|Rep:
D-3-phosphoglycerate dehydrogenase - Lactobacillus
salivarius subsp. salivarius (strain UCC118)
Length = 394
Score = 50.4 bits (115), Expect = 6e-05
Identities = 28/73 (38%), Positives = 40/73 (54%)
Frame = +1
Query: 259 DALVVRSATQVTKEVLDAGVKLKVVGRAGAGVDNIDVXSAGKKGVGVINAPGANALSACE 438
DAL++RS G + + RAGAGV+NI + A +G V N PG+NA + E
Sbjct: 32 DALLIRSQDM---HKTPFGTSVLAIARAGAGVNNIPLEKATSQGTAVFNTPGSNANAVKE 88
Query: 439 LTCTLMLVLARHV 477
L T++L+ R V
Sbjct: 89 LIITMLLLSVRPV 101
Score = 37.5 bits (83), Expect = 0.43
Identities = 15/40 (37%), Positives = 23/40 (57%)
Frame = +3
Query: 525 YTGSELAGXXLXILGLGRVGXXVATXMYAFXMNIIGFQPF 644
+ G+EL G + I+GLG +G VA M +IG+ P+
Sbjct: 127 FAGTELYGKKIGIIGLGNIGSRVAKACMDLGMKVIGYDPY 166
>UniRef50_A7NGZ0 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase NAD-binding; n=1; Roseiflexus castenholzii
DSM 13941|Rep: D-isomer specific 2-hydroxyacid
dehydrogenase NAD-binding - Roseiflexus castenholzii DSM
13941
Length = 345
Score = 50.4 bits (115), Expect = 6e-05
Identities = 28/79 (35%), Positives = 41/79 (51%), Gaps = 1/79 (1%)
Frame = +1
Query: 247 IPNHDALVVRSATQVTKEVLD-AGVKLKVVGRAGAGVDNIDVXSAGKKGVGVINAPGANA 423
+P A ++ + +D AG L + R G GVDNID+ +A ++G+ VIN P
Sbjct: 44 LPGSAAAIISAMINADGAWMDRAGPTLMAIARPGIGVDNIDLAAATERGILVINTPDGPT 103
Query: 424 LSACELTCTLMLVLARHVV 480
S E L+L LA+ VV
Sbjct: 104 ESTAEHAVALVLALAKQVV 122
>UniRef50_A6G855 Cluster: Erythronate-4-phosphate dehydrogenase;
n=1; Plesiocystis pacifica SIR-1|Rep:
Erythronate-4-phosphate dehydrogenase - Plesiocystis
pacifica SIR-1
Length = 397
Score = 50.4 bits (115), Expect = 6e-05
Identities = 26/66 (39%), Positives = 40/66 (60%)
Frame = +1
Query: 262 ALVVRSATQVTKEVLDAGVKLKVVGRAGAGVDNIDVXSAGKKGVGVINAPGANALSACEL 441
ALVVRS T V +LDA +L+ VG A AG+D++D+ + + V V +A G N+L+ +
Sbjct: 45 ALVVRSVTTVDAALLDACPELEFVGTATAGLDHLDLEALAAREVAVADAAGCNSLAVAQW 104
Query: 442 TCTLML 459
+L
Sbjct: 105 VAAALL 110
>UniRef50_Q4PK14 Cluster: Predicted D-isomer specific 2-hydroxyacid
dehydrogenase family protein; n=1; uncultured bacterium
MedeBAC49C08|Rep: Predicted D-isomer specific
2-hydroxyacid dehydrogenase family protein - uncultured
bacterium MedeBAC49C08
Length = 395
Score = 50.0 bits (114), Expect = 8e-05
Identities = 27/73 (36%), Positives = 42/73 (57%)
Frame = +1
Query: 259 DALVVRSATQVTKEVLDAGVKLKVVGRAGAGVDNIDVXSAGKKGVGVINAPGANALSACE 438
DA+++RS E+ + +K + RAGAGV+NI V K G+ V N PGANA + E
Sbjct: 34 DAIILRSHKLQMSEIPSS---VKAIVRAGAGVNNIPVEECSKIGIPVFNTPGANANAVKE 90
Query: 439 LTCTLMLVLARHV 477
+ +L+ +R +
Sbjct: 91 MVLAALLMSSRGI 103
Score = 33.5 bits (73), Expect = 7.1
Identities = 22/79 (27%), Positives = 33/79 (41%), Gaps = 2/79 (2%)
Frame = +3
Query: 525 YTGSELAGXXLXILGLGRVGXXVATXMYAFXMNIIGFQPFRVC*SVRPVP--LHXXGAGG 698
+ G EL L ++G+G +G VA M +IGF P + +P +
Sbjct: 132 FKGRELKDGCLGVVGMGAIGAKVAEMGVMLGMRVIGFDPQITVEAAWALPNEVERKETIE 191
Query: 699 XFGPLTDXITLHTPVIEXT 755
+D +TLH P E T
Sbjct: 192 EIFKESDYVTLHVPANEHT 210
>UniRef50_Q1MQK2 Cluster: Phosphoglycerate dehydrogenase and related
dehydrogenases; n=1; Lawsonia intracellularis
PHE/MN1-00|Rep: Phosphoglycerate dehydrogenase and
related dehydrogenases - Lawsonia intracellularis
(strain PHE/MN1-00)
Length = 302
Score = 50.0 bits (114), Expect = 8e-05
Identities = 34/107 (31%), Positives = 54/107 (50%), Gaps = 3/107 (2%)
Frame = +1
Query: 166 KCAELLNAYGIATTTKAK---ISKEELLMEIPNHDALVVRSATQVTKEVLDAGVKLKVVG 336
K ELL+ GI + ++ EEL+ I ++V S + K+VL+ +LK +
Sbjct: 16 KPLELLSQAGIEYILNEQGYHLTDEELIQIIDGCAGIIVGSEP-LPKKVLETNPRLKTIA 74
Query: 337 RAGAGVDNIDVXSAGKKGVGVINAPGANALSACELTCTLMLVLARHV 477
G +DNIDV A +K + + N P A++ E T L+L L R +
Sbjct: 75 CCGKHLDNIDVEYAQEKNIIIYNPPKGYAIAVAEFTVGLILSLIRQI 121
>UniRef50_Q27SS3 Cluster: Glycerate dehydrogenase-like protein; n=2;
Eukaryota|Rep: Glycerate dehydrogenase-like protein -
Trimastix pyriformis
Length = 232
Score = 50.0 bits (114), Expect = 8e-05
Identities = 25/87 (28%), Positives = 49/87 (56%)
Frame = +1
Query: 223 SKEELLMEIPNHDALVVRSATQVTKEVLDAGVKLKVVGRAGAGVDNIDVXSAGKKGVGVI 402
+++EL+ D + + ++ +E+L+ +L+VV G +NID+ +A ++ V V
Sbjct: 34 TRDELVSGFQWADGALTMLSDKIDRELLEVAPRLRVVANYAVGYNNIDLTAANERHVVVT 93
Query: 403 NAPGANALSACELTCTLMLVLARHVVQ 483
N P A + +LT L+L +AR +V+
Sbjct: 94 NTPHCLAEATADLTMGLLLAVARRLVE 120
>UniRef50_Q65DI8 Cluster: Putative uncharacterized protein; n=1;
Bacillus licheniformis ATCC 14580|Rep: Putative
uncharacterized protein - Bacillus licheniformis (strain
DSM 13 / ATCC 14580)
Length = 101
Score = 49.6 bits (113), Expect = 1e-04
Identities = 23/66 (34%), Positives = 42/66 (63%)
Frame = +1
Query: 217 KISKEELLMEIPNHDALVVRSATQVTKEVLDAGVKLKVVGRAGAGVDNIDVXSAGKKGVG 396
++++++LL I + + + + +E++DA L+ + + GAG+DNIDV A +KG+
Sbjct: 37 RLTRQDLLTHIKDVH-IYIAGVEKADRELIDAAPGLRYIMKFGAGIDNIDVEYANEKGIL 95
Query: 397 VINAPG 414
V NAPG
Sbjct: 96 VTNAPG 101
>UniRef50_Q5ZYW9 Cluster: D-3-phosphoglycerate dehydrogenase; n=3;
Legionella pneumophila|Rep: D-3-phosphoglycerate
dehydrogenase - Legionella pneumophila subsp.
pneumophila (strain Philadelphia 1 /ATCC 33152 / DSM
7513)
Length = 295
Score = 49.6 bits (113), Expect = 1e-04
Identities = 30/116 (25%), Positives = 63/116 (54%), Gaps = 3/116 (2%)
Frame = +1
Query: 139 VLIVDGVGAKCAEL---LNAYGIATTTKAKISKEELLMEIPNHDALVVRSATQVTKEVLD 309
+ +V+ +G E+ L + I + S E+L+ + + D + + + +++ V++
Sbjct: 3 IAVVEPIGIAMQEIRSELPGHTIIECDSRQWSDEQLIDFVKDADIIALTNR-RLSAAVIN 61
Query: 310 AGVKLKVVGRAGAGVDNIDVXSAGKKGVGVINAPGANALSACELTCTLMLVLARHV 477
+ ++L+++ A AG+D+ID + K+ + V NA G + EL LM+ LARH+
Sbjct: 62 SALRLQLIAVAFAGIDHIDRDAVSKRNIPVKNAAGYANTAVSELVFGLMISLARHI 117
>UniRef50_Q0FY56 Cluster: Putative phosphoglycerate dehydrogenase
protein; n=1; Fulvimarina pelagi HTCC2506|Rep: Putative
phosphoglycerate dehydrogenase protein - Fulvimarina
pelagi HTCC2506
Length = 322
Score = 49.6 bits (113), Expect = 1e-04
Identities = 29/80 (36%), Positives = 43/80 (53%)
Frame = +1
Query: 244 EIPNHDALVVRSATQVTKEVLDAGVKLKVVGRAGAGVDNIDVXSAGKKGVGVINAPGANA 423
E+ +VVR A + L+ KL+ + R GAG+D I V +A + G+ V N P NA
Sbjct: 35 ELAEASFVVVRRA--IPAGALENAPKLRALVRHGAGLDFIPVQAASRLGIAVTNTPSVNA 92
Query: 424 LSACELTCTLMLVLARHVVQ 483
S E L++ LAR +V+
Sbjct: 93 KSVAEHVFGLIICLARRIVE 112
>UniRef50_Q9K7P7 Cluster: Glycerate dehydrogenase; n=8;
Bacillaceae|Rep: Glycerate dehydrogenase - Bacillus
halodurans
Length = 324
Score = 49.2 bits (112), Expect = 1e-04
Identities = 26/92 (28%), Positives = 41/92 (44%)
Frame = +1
Query: 202 TTTKAKISKEELLMEIPNHDALVVRSATQVTKEVLDAGVKLKVVGRAGAGVDNIDVXSAG 381
T + +E L E+ D + + E + +LKVV G DNID+ A
Sbjct: 27 TEENIPMPRELFLKELEEADGVFTNLTDRFDVEAFERAKRLKVVSTMAVGYDNIDIKEAT 86
Query: 382 KKGVGVINAPGANALSACELTCTLMLVLARHV 477
K+GV V + PG + +LT L++ R +
Sbjct: 87 KRGVSVGHTPGVLTEATADLTFALLMATGRRL 118
>UniRef50_Q5KYJ7 Cluster: Dehydrogenase; n=3; Firmicutes|Rep:
Dehydrogenase - Geobacillus kaustophilus
Length = 334
Score = 49.2 bits (112), Expect = 1e-04
Identities = 29/105 (27%), Positives = 57/105 (54%)
Frame = +1
Query: 175 ELLNAYGIATTTKAKISKEELLMEIPNHDALVVRSATQVTKEVLDAGVKLKVVGRAGAGV 354
E+L++ + ++EE++ + DA++ + A ++ EV+ K K++ R G GV
Sbjct: 21 EVLSSLNVEFVATQCRTEEEVISACRDADAIINQYAP-ISAEVIAQLEKCKIISRYGVGV 79
Query: 355 DNIDVXSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVQLH 489
+ +DV +A +KG+ V N + + L+L LAR +V+L+
Sbjct: 80 NTVDVDAATEKGIIVANVTDYSIDEVSDHALALLLSLARKIVKLN 124
>UniRef50_Q1VRN5 Cluster: D-3-phosphoglycerate dehydrogenase; n=1;
Psychroflexus torquis ATCC 700755|Rep:
D-3-phosphoglycerate dehydrogenase - Psychroflexus
torquis ATCC 700755
Length = 326
Score = 49.2 bits (112), Expect = 1e-04
Identities = 34/115 (29%), Positives = 57/115 (49%), Gaps = 2/115 (1%)
Frame = +1
Query: 139 VLIVDGVGAKCAELLNAYGIATTTKAKISKEELLMEIPNH--DALVVRSATQVTKEVLDA 312
+L DG+ +LL G K K+++ +L I + D ++V+ +T +TK +L
Sbjct: 12 ILATDGLSGIGVQLLENAGHEVIIK-KVAQNQLSEYITTNEFDGVLVKRSTPLTKVILSE 70
Query: 313 GVKLKVVGRAGAGVDNIDVXSAGKKGVGVINAPGANALSACELTCTLMLVLARHV 477
LK +G +ID+ A +KG+ V A A++ S ELT +L RH+
Sbjct: 71 SPTLKFIGNCDIISTHIDIDFAEQKGLSVFQAITASSNSIAELTIGHLLSCVRHL 125
>UniRef50_A6CRV0 Cluster: 2-hydroxyacid dehydrogenase; n=15;
Bacillales|Rep: 2-hydroxyacid dehydrogenase - Bacillus
sp. SG-1
Length = 351
Score = 49.2 bits (112), Expect = 1e-04
Identities = 25/88 (28%), Positives = 44/88 (50%)
Frame = +1
Query: 220 ISKEELLMEIPNHDALVVRSATQVTKEVLDAGVKLKVVGRAGAGVDNIDVXSAGKKGVGV 399
+ +E LL + ++ + + +E+ + LKVV G DNID+ +A +K V V
Sbjct: 61 VPREILLEKAGEASGILSMLSDPIDRELFEKSPNLKVVANLAVGFDNIDLKAANEKDVAV 120
Query: 400 INAPGANALSACELTCTLMLVLARHVVQ 483
N P + +LT LM+ AR +++
Sbjct: 121 CNTPDVLTDTTADLTFGLMMAAARRLIE 148
>UniRef50_A5CWD1 Cluster: Erythronate-4-phosphate dehydrogenase;
n=3; Bacteria|Rep: Erythronate-4-phosphate dehydrogenase
- Vesicomyosocius okutanii subsp. Calyptogena okutanii
(strain HA)
Length = 345
Score = 49.2 bits (112), Expect = 1e-04
Identities = 31/109 (28%), Positives = 54/109 (49%)
Frame = +1
Query: 142 LIVDGVGAKCAELLNAYGIATTTKAKISKEELLMEIPNHDALVVRSATQVTKEVLDAGVK 321
L++D E+ + +G +T + + N D L+VRS T+V +LD G +
Sbjct: 3 LVIDDACYAHKEIFSHFGNISTIAGRDINST---SVKNADILIVRSRTKVNHVLLD-GSQ 58
Query: 322 LKVVGRAGAGVDNIDVXSAGKKGVGVINAPGANALSACELTCTLMLVLA 468
+K VG G+D+ID KG+ +A G N+++ E + ++ LA
Sbjct: 59 VKFVGSTVTGLDHIDQDYLKSKGIKFFSAQGCNSMAVAEFVISAIVNLA 107
>UniRef50_Q031D4 Cluster: Phosphoglycerate dehydrogenase; n=20;
Streptococcaceae|Rep: Phosphoglycerate dehydrogenase -
Lactococcus lactis subsp. cremoris (strain SK11)
Length = 398
Score = 48.8 bits (111), Expect = 2e-04
Identities = 22/53 (41%), Positives = 33/53 (62%)
Frame = +1
Query: 319 KLKVVGRAGAGVDNIDVXSAGKKGVGVINAPGANALSACELTCTLMLVLARHV 477
+L +GRAGAG +NI + KG+ V NAPG NA + EL ++M+ R++
Sbjct: 52 ELLAIGRAGAGFNNIPIEKCASKGIVVFNAPGGNANAVKELVLSMMIFGTRNL 104
Score = 43.2 bits (97), Expect = 0.009
Identities = 23/79 (29%), Positives = 36/79 (45%), Gaps = 2/79 (2%)
Frame = +3
Query: 525 YTGSELAGXXLXILGLGRVGXXVATXMYAFXMNIIGFQPFRVC*SVRPVPLHXXGAG--G 698
++GSE++G L ++GLG +G VA M +IG+ P+ + H
Sbjct: 132 FSGSEISGKTLGVIGLGNIGSKVANDAQRLGMKVIGYDPYLSIEHAWNLSHHVKRVNDLS 191
Query: 699 XFGPLTDXITLHTPVIEXT 755
D IT+HTP + T
Sbjct: 192 EIFEKADYITVHTPATDET 210
>UniRef50_A6G5P3 Cluster: D-3-phosphoglycerate dehydrogenase; n=1;
Plesiocystis pacifica SIR-1|Rep: D-3-phosphoglycerate
dehydrogenase - Plesiocystis pacifica SIR-1
Length = 405
Score = 48.8 bits (111), Expect = 2e-04
Identities = 26/71 (36%), Positives = 38/71 (53%)
Frame = +1
Query: 271 VRSATQVTKEVLDAGVKLKVVGRAGAGVDNIDVXSAGKKGVGVINAPGANALSACELTCT 450
VRS T+V + +A +L VG G D ID+ A + GV V NAP +N S EL
Sbjct: 49 VRSKTKVRAPIFEAVPRLAAVGAFCIGTDQIDLEVAAQSGVAVFNAPFSNTRSVAELVIA 108
Query: 451 LMLVLARHVVQ 483
++ L+R + +
Sbjct: 109 EIVCLSRQLFE 119
>UniRef50_A0Z6W9 Cluster: Spermidine/putrescine ABC transporter
ATP-binding subunit; n=4; Bacteria|Rep:
Spermidine/putrescine ABC transporter ATP-binding
subunit - marine gamma proteobacterium HTCC2080
Length = 395
Score = 48.8 bits (111), Expect = 2e-04
Identities = 27/79 (34%), Positives = 44/79 (55%)
Frame = +1
Query: 244 EIPNHDALVVRSATQVTKEVLDAGVKLKVVGRAGAGVDNIDVXSAGKKGVGVINAPGANA 423
EI + DA+++RS E+ + + RAGAGV+NI + + G+ V N PGANA
Sbjct: 28 EIGSADAMLLRSHKLQADEI---SASVTAIARAGAGVNNIPLSHCTELGIPVFNTPGANA 84
Query: 424 LSACELTCTLMLVLARHVV 480
+ EL +L+ +R ++
Sbjct: 85 NAVKELVAAGLLLASRDIL 103
Score = 40.7 bits (91), Expect = 0.046
Identities = 25/82 (30%), Positives = 37/82 (45%), Gaps = 2/82 (2%)
Frame = +3
Query: 525 YTGSELAGXXLXILGLGRVGXXVATXMYAFXMNIIGFQPFRVC*SVRPVPLHXXGAGGXF 704
+ G+EL G L +LGLG +G VA M+++GF P + +P
Sbjct: 132 FAGAELKGKTLGVLGLGAIGSLVAQLGLELGMDVVGFDPAISIEAAWQLPSSVKRMENMQ 191
Query: 705 GPLT--DXITLHTPVIEXTXXL 764
+ D I++H P IE T L
Sbjct: 192 ALFSRADYISIHVPAIESTHHL 213
>UniRef50_A0Y9Y1 Cluster: Glyoxylate reductase; n=2; unclassified
Gammaproteobacteria|Rep: Glyoxylate reductase - marine
gamma proteobacterium HTCC2143
Length = 326
Score = 48.8 bits (111), Expect = 2e-04
Identities = 23/91 (25%), Positives = 46/91 (50%)
Frame = +1
Query: 211 KAKISKEELLMEIPNHDALVVRSATQVTKEVLDAGVKLKVVGRAGAGVDNIDVXSAGKKG 390
K I ++EL+ + D ++ ++ E++++ LK V GVD++DV + +G
Sbjct: 30 KGSIPRDELMARVEGVDGIICLLTERIDGELINSSKNLKAVSCVSVGVDHVDVGTLTARG 89
Query: 391 VGVINAPGANALSACELTCTLMLVLARHVVQ 483
+ + + PG + +L L+L AR + Q
Sbjct: 90 IPLGHTPGVLVDATADLAFGLLLAAARRIPQ 120
>UniRef50_A2D764 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase, putative; n=1; Trichomonas vaginalis
G3|Rep: D-isomer specific 2-hydroxyacid dehydrogenase,
putative - Trichomonas vaginalis G3
Length = 136
Score = 48.8 bits (111), Expect = 2e-04
Identities = 27/88 (30%), Positives = 49/88 (55%)
Frame = +1
Query: 220 ISKEELLMEIPNHDALVVRSATQVTKEVLDAGVKLKVVGRAGAGVDNIDVXSAGKKGVGV 399
++++E L N D + R + + K+VLD+ KLK+V A AG D ID+ A K+G+ V
Sbjct: 44 MTRKEFLEHARNADVIYARGSDLINKDVLDSP-KLKMVSAAAAGADKIDMEYATKRGIIV 102
Query: 400 INAPGANALSACELTCTLMLVLARHVVQ 483
N + A + + +++ +R +V+
Sbjct: 103 SNTHLSLADTYADTLMGILIACSRRIVE 130
>UniRef50_Q7UQC8 Cluster: Probable 2-hydroxyacid dehydrogenase; n=1;
Pirellula sp.|Rep: Probable 2-hydroxyacid dehydrogenase
- Rhodopirellula baltica
Length = 406
Score = 48.4 bits (110), Expect = 2e-04
Identities = 28/87 (32%), Positives = 46/87 (52%), Gaps = 1/87 (1%)
Frame = +1
Query: 223 SKEELLMEIPNHDALVVRSATQVTKEVLD-AGVKLKVVGRAGAGVDNIDVXSAGKKGVGV 399
S+EEL + L+ + ++ E++D AG +L VV G +NIDV +A +GV V
Sbjct: 120 SREELCRLVKGRHGLLTMLSDRIDGELMDVAGEQLCVVSNYAVGFNNIDVDAAKTRGVVV 179
Query: 400 INAPGANALSACELTCTLMLVLARHVV 480
N P + +L +L+ +RHV+
Sbjct: 180 GNTPDVLTDATADLAVSLLFAASRHVL 206
>UniRef50_Q1N6E5 Cluster: Erythronate-4-phosphate dehydrogenase;
n=1; Oceanobacter sp. RED65|Rep: Erythronate-4-phosphate
dehydrogenase - Oceanobacter sp. RED65
Length = 377
Score = 48.4 bits (110), Expect = 2e-04
Identities = 25/75 (33%), Positives = 43/75 (57%)
Frame = +1
Query: 244 EIPNHDALVVRSATQVTKEVLDAGVKLKVVGRAGAGVDNIDVXSAGKKGVGVINAPGANA 423
++ + D L+VRS T+V + +L G K++ VG G D++D + G+ NAPG NA
Sbjct: 35 DVADADILLVRSITKVDQALLQ-GSKVRFVGTCTIGTDHLDTDYLEQAGIKWANAPGCNA 93
Query: 424 LSACELTCTLMLVLA 468
+ + + MLV++
Sbjct: 94 KAVVDYVLSCMLVIS 108
>UniRef50_A1W9A3 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase, NAD-binding; n=1; Acidovorax sp.
JS42|Rep: D-isomer specific 2-hydroxyacid dehydrogenase,
NAD-binding - Acidovorax sp. (strain JS42)
Length = 339
Score = 48.4 bits (110), Expect = 2e-04
Identities = 25/77 (32%), Positives = 41/77 (53%)
Frame = +1
Query: 259 DALVVRSATQVTKEVLDAGVKLKVVGRAGAGVDNIDVXSAGKKGVGVINAPGANALSACE 438
+ L V T+V + VL +L++V AG D+ID+ + K+G+ V + P + S E
Sbjct: 51 EVLCVFVRTRVDESVLRMLPRLRLVATRSAGFDHIDLEACRKRGIAVCHVPDYGSASVAE 110
Query: 439 LTCTLMLVLARHVVQLH 489
L+L + RH+ Q H
Sbjct: 111 HAFALLLGVTRHLTQAH 127
Score = 44.4 bits (100), Expect = 0.004
Identities = 26/79 (32%), Positives = 37/79 (46%)
Frame = +3
Query: 528 TGSELAGXXLXILGLGRVGXXVATXMYAFXMNIIGFQPFRVC*SVRPVPLHXXGAGGXFG 707
TG EL G L I+GLGR+G VA F M+++ + P + RP +
Sbjct: 141 TGFELEGRTLGIVGLGRIGRHVARIAVGFGMDVLAYDPAFAASAARPAGVSLVTWEQVLQ 200
Query: 708 PLTDXITLHTPVIEXTXXL 764
+D ++LH P E T L
Sbjct: 201 G-SDILSLHVPATEATRHL 218
>UniRef50_Q6AMI7 Cluster: Related to D-3-phosphoglycerate
dehydrogenase; n=1; Desulfotalea psychrophila|Rep:
Related to D-3-phosphoglycerate dehydrogenase -
Desulfotalea psychrophila
Length = 393
Score = 48.0 bits (109), Expect = 3e-04
Identities = 23/52 (44%), Positives = 33/52 (63%)
Frame = +1
Query: 322 LKVVGRAGAGVDNIDVXSAGKKGVGVINAPGANALSACELTCTLMLVLARHV 477
L V RAGAG +N++V A KKG+ V N PGANA + +L ++ V R++
Sbjct: 51 LLAVARAGAGTNNVNVERATKKGICVFNTPGANANAVVDLVFPMLGVWKRNI 102
Score = 38.7 bits (86), Expect = 0.19
Identities = 23/85 (27%), Positives = 40/85 (47%), Gaps = 2/85 (2%)
Frame = +3
Query: 516 RALYTGSELAGXXLXILGLGRVGXXVATXMYAFXMNIIGFQPFRVC*SVRPVPLHXXGAG 695
++ Y G E+AG L ++GLG++G +A MN+ GF P ++ +
Sbjct: 128 KSAYKGEEIAGKNLTVVGLGQIGVRLANGGIQRLMNVKGFDPAPALENIHQLSPQVRVCR 187
Query: 696 GXFGPLT--DXITLHTPVIEXTXXL 764
++ D I+LH P+ + T L
Sbjct: 188 ALKDAVSDADVISLHLPLNDRTRNL 212
>UniRef50_Q49UN3 Cluster: NAD-dependent formate dehydrogenase; n=13;
Staphylococcus|Rep: NAD-dependent formate dehydrogenase
- Staphylococcus saprophyticus subsp. saprophyticus
(strain ATCC 15305 /DSM 20229)
Length = 389
Score = 48.0 bits (109), Expect = 3e-04
Identities = 22/67 (32%), Positives = 39/67 (58%)
Frame = +1
Query: 289 VTKEVLDAGVKLKVVGRAGAGVDNIDVXSAGKKGVGVINAPGANALSACELTCTLMLVLA 468
+TKE ++ LK+V AG G D++D+ +A + +GV+ G+N +S E +L+L
Sbjct: 116 MTKERIEKAPNLKLVITAGVGSDHVDLQAASEHNIGVVEVTGSNTISVAEHAVMDLLILL 175
Query: 469 RHVVQLH 489
R+ + H
Sbjct: 176 RNYEEGH 182
>UniRef50_Q13ZE9 Cluster: Putative dehydrogenase,
D-3-phosphoglycerate dehydrogenase-like; n=1;
Burkholderia xenovorans LB400|Rep: Putative
dehydrogenase, D-3-phosphoglycerate dehydrogenase-like -
Burkholderia xenovorans (strain LB400)
Length = 354
Score = 48.0 bits (109), Expect = 3e-04
Identities = 21/71 (29%), Positives = 38/71 (53%)
Frame = +1
Query: 259 DALVVRSATQVTKEVLDAGVKLKVVGRAGAGVDNIDVXSAGKKGVGVINAPGANALSACE 438
DA++V ++T+EV+ + +++ R G G DN+D + ++G+ V N P +
Sbjct: 60 DAILVWHRMKITREVVSRLSRCRMIVRVGVGFDNVDTAACSERGIPVSNVPNYGTTEVAD 119
Query: 439 LTCTLMLVLAR 471
+ML LAR
Sbjct: 120 HAIAMMLYLAR 130
>UniRef50_A4SWE6 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase, NAD-binding; n=4; Bacteria|Rep: D-isomer
specific 2-hydroxyacid dehydrogenase, NAD-binding -
Polynucleobacter sp. QLW-P1DMWA-1
Length = 326
Score = 48.0 bits (109), Expect = 3e-04
Identities = 24/87 (27%), Positives = 45/87 (51%), Gaps = 1/87 (1%)
Frame = +1
Query: 220 ISKEELLMEIPNHDALVVRSATQVTKEVLDA-GVKLKVVGRAGAGVDNIDVXSAGKKGVG 396
+++EEL+ + DA++ V E+LDA G + K++ G +N ++ +A K+GV
Sbjct: 35 LTREELMNAVKGRDAVITLLTDNVDAEILDAAGPQCKIIANYAVGFNNFNLDAATKRGVI 94
Query: 397 VINAPGANALSACELTCTLMLVLARHV 477
+ N PG + L+L A+ +
Sbjct: 95 MTNTPGVLDKATATHAWALLLATAKRI 121
>UniRef50_Q3A6W9 Cluster: 3-phosphoglycerate dehydrogenase; n=1;
Pelobacter carbinolicus DSM 2380|Rep: 3-phosphoglycerate
dehydrogenase - Pelobacter carbinolicus (strain DSM 2380
/ Gra Bd 1)
Length = 321
Score = 47.6 bits (108), Expect = 4e-04
Identities = 22/78 (28%), Positives = 43/78 (55%)
Frame = +1
Query: 247 IPNHDALVVRSATQVTKEVLDAGVKLKVVGRAGAGVDNIDVXSAGKKGVGVINAPGANAL 426
I + +AL+ RS +T ++ L+++ RAG+G+DN+D+ + ++ P A
Sbjct: 38 IRDREALIFRSGVNITAGIMACAPDLQLLIRAGSGLDNVDLDYLRNHDLKLVRIPQPGAR 97
Query: 427 SACELTCTLMLVLARHVV 480
+ EL +ML L+R ++
Sbjct: 98 AVAELAFGMMLALSRQIL 115
>UniRef50_Q04DF1 Cluster: Lactate dehydrogenase related enzyme; n=1;
Oenococcus oeni PSU-1|Rep: Lactate dehydrogenase related
enzyme - Oenococcus oeni (strain BAA-331 / PSU-1)
Length = 311
Score = 47.6 bits (108), Expect = 4e-04
Identities = 26/92 (28%), Positives = 46/92 (50%)
Frame = +1
Query: 211 KAKISKEELLMEIPNHDALVVRSATQVTKEVLDAGVKLKVVGRAGAGVDNIDVXSAGKKG 390
+A K+E ++++ +V + L LK++ R G G DN+D AG+ G
Sbjct: 26 EAPDDKQETILKVGKDADGIVLMTDPFDNQTLTKFTNLKIIARHGVGFDNVDEKFAGEHG 85
Query: 391 VGVINAPGANALSACELTCTLMLVLARHVVQL 486
V V P ANA + E T +L L++++ ++
Sbjct: 86 VYVTITPMANASTVAETTIAEILDLSKNLTKI 117
>UniRef50_A4B0Y8 Cluster: Erythronate-4-phosphate dehydrogenase;
n=1; Alteromonas macleodii 'Deep ecotype'|Rep:
Erythronate-4-phosphate dehydrogenase - Alteromonas
macleodii 'Deep ecotype'
Length = 402
Score = 47.6 bits (108), Expect = 4e-04
Identities = 30/95 (31%), Positives = 50/95 (52%)
Frame = +1
Query: 175 ELLNAYGIATTTKAKISKEELLMEIPNHDALVVRSATQVTKEVLDAGVKLKVVGRAGAGV 354
+ LN+ G T + E+L ++ D L +RS T+VT E+L + KLK V A AG+
Sbjct: 14 DYLNSVGEVETYAWQSLVPEMLRDV---DILALRSTTKVTPELLISASKLKFVTTATAGI 70
Query: 355 DNIDVXSAGKKGVGVINAPGANALSACELTCTLML 459
+++D G+ +A G NA++ E + +L
Sbjct: 71 NHLDKTHLDSVGIMHSSAAGCNAVAVAEYVLSALL 105
>UniRef50_Q20595 Cluster: Putative uncharacterized protein; n=3;
Caenorhabditis|Rep: Putative uncharacterized protein -
Caenorhabditis elegans
Length = 727
Score = 47.6 bits (108), Expect = 4e-04
Identities = 30/84 (35%), Positives = 48/84 (57%), Gaps = 1/84 (1%)
Frame = +1
Query: 223 SKEELLMEIPNHD-ALVVRSATQVTKEVLDAGVKLKVVGRAGAGVDNIDVXSAGKKGVGV 399
S +E+ ++ N A ++ + ++ KE L+ LKVV R G G+DNIDV +A + G+ V
Sbjct: 209 STQEIHEKVLNEAVAALMYHSIKLEKEDLEKFKVLKVVFRIGYGIDNIDVKAATELGIAV 268
Query: 400 INAPGANALSACELTCTLMLVLAR 471
+APG + T +L+L L R
Sbjct: 269 CHAPGDYVEDVADSTLSLILDLFR 292
Score = 33.5 bits (73), Expect = 7.1
Identities = 27/90 (30%), Positives = 39/90 (43%)
Frame = +3
Query: 537 ELAGXXLXILGLGRVGXXVATXMYAFXMNIIGFQPFRVC*SVRPVPLHXXGAGGXFGPLT 716
++ G L ILG GRVG V AF ++II + PF + + F +
Sbjct: 322 KVRGSVLGILGCGRVGTAVGLRARAFGLHIIFYDPFVREGHDKALGFERVYTMDEFMSRS 381
Query: 717 DXITLHTPVIEXTXXLYPXPMS*XQCXKGV 806
D I+LH + + T + S QC GV
Sbjct: 382 DCISLHCNLGDETRGIINAD-SLRQCKSGV 410
>UniRef50_Q8A2E4 Cluster: Erythronate-4-phosphate dehydrogenase;
n=5; Bacteroides|Rep: Erythronate-4-phosphate
dehydrogenase - Bacteroides thetaiotaomicron
Length = 348
Score = 47.6 bits (108), Expect = 4e-04
Identities = 23/72 (31%), Positives = 41/72 (56%)
Frame = +1
Query: 247 IPNHDALVVRSATQVTKEVLDAGVKLKVVGRAGAGVDNIDVXSAGKKGVGVINAPGANAL 426
+ + DAL++R+ T +E+L+ G K+K + A G D+ID + G+ NAPG N+
Sbjct: 36 VQDADALIIRTRTHCNRELLE-GSKVKFIATATIGFDHIDTEYCKQAGIEWANAPGCNSA 94
Query: 427 SACELTCTLMLV 462
S + + +L+
Sbjct: 95 SVAQYIQSSLLI 106
>UniRef50_A4U158 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase, catalytic region:D- isomer specific
2-hydroxyacid dehydrogenase, NAD-binding; n=4;
Proteobacteria|Rep: D-isomer specific 2-hydroxyacid
dehydrogenase, catalytic region:D- isomer specific
2-hydroxyacid dehydrogenase, NAD-binding -
Magnetospirillum gryphiswaldense
Length = 319
Score = 47.2 bits (107), Expect = 5e-04
Identities = 33/103 (32%), Positives = 49/103 (47%), Gaps = 2/103 (1%)
Frame = +1
Query: 175 ELLNAYGIAT--TTKAKISKEELLMEIPNHDALVVRSATQVTKEVLDAGVKLKVVGRAGA 348
EL YG T T A +S E L+ + HD + + ++ +VL +L+VVG+ G
Sbjct: 25 ELTQRYGQVTFNETGASLSGESLVAFLDGHDKAIT-ALERLNGDVLARLPRLRVVGKYGV 83
Query: 349 GVDNIDVXSAGKKGVGVINAPGANALSACELTCTLMLVLARHV 477
G+D ID+ + G + G N S EL + L RHV
Sbjct: 84 GLDMIDLPAMSALGKKLGWTGGVNRRSVSELVIAATISLLRHV 126
>UniRef50_A1HQU2 Cluster: Glyoxylate reductase; n=1; Thermosinus
carboxydivorans Nor1|Rep: Glyoxylate reductase -
Thermosinus carboxydivorans Nor1
Length = 324
Score = 47.2 bits (107), Expect = 5e-04
Identities = 25/82 (30%), Positives = 44/82 (53%), Gaps = 1/82 (1%)
Frame = +1
Query: 235 LLME-IPNHDALVVRSATQVTKEVLDAGVKLKVVGRAGAGVDNIDVXSAGKKGVGVINAP 411
LL E + + + LV +V E+L +L+V+ +A G DN+D+ + ++G+ N P
Sbjct: 39 LLYEWLADAEGLVSTGDVRVDDELLAHAPRLRVIAQASVGYDNVDIAACTRRGIPFGNTP 98
Query: 412 GANALSACELTCTLMLVLARHV 477
G + +LT L+L AR +
Sbjct: 99 GVLVEATADLTFGLLLCAARRI 120
>UniRef50_A0GDF1 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase, NAD-binding; n=1; Burkholderia
phytofirmans PsJN|Rep: D-isomer specific 2-hydroxyacid
dehydrogenase, NAD-binding - Burkholderia phytofirmans
PsJN
Length = 274
Score = 47.2 bits (107), Expect = 5e-04
Identities = 22/72 (30%), Positives = 42/72 (58%)
Frame = +1
Query: 265 LVVRSATQVTKEVLDAGVKLKVVGRAGAGVDNIDVXSAGKKGVGVINAPGANALSACELT 444
+V ++ +VLD L+++G AGV+++D + K+G+G++ PG + +S E
Sbjct: 10 IVFLDRATLSGDVLDQLPHLELIGVPAAGVNHLDTETCRKRGIGIVACPGYSTISVPEHA 69
Query: 445 CTLMLVLARHVV 480
LML L R+++
Sbjct: 70 FALMLALRRNLM 81
>UniRef50_Q4PP80 Cluster: Putative glyoxylate
reductase/hydroxypyruvate reductase; n=1; Lysiphlebus
testaceipes|Rep: Putative glyoxylate
reductase/hydroxypyruvate reductase - Lysiphlebus
testaceipes (Greenbugs aphid parastoid)
Length = 325
Score = 47.2 bits (107), Expect = 5e-04
Identities = 29/103 (28%), Positives = 51/103 (49%), Gaps = 2/103 (1%)
Frame = +1
Query: 178 LLNAYGIATTTKAK-ISKEELLMEIPNHDALVVRSATQVTKEVLD-AGVKLKVVGRAGAG 351
L N Y + K I + E L + + D + ++ +E+L AG KLKVV G
Sbjct: 21 LKNKYDLICWNKTTPIPRTEFLSMVKDVDGIFCLLTDKIDEEILSTAGSKLKVVSTMSVG 80
Query: 352 VDNIDVXSAGKKGVGVINAPGANALSACELTCTLMLVLARHVV 480
+D++++ + +G+ V PG + ELT L+L +R ++
Sbjct: 81 LDHLNLNALKTRGIHVGYTPGVLTDATAELTIGLLLATSRKII 123
>UniRef50_P13443 Cluster: Glycerate dehydrogenase; n=15;
Viridiplantae|Rep: Glycerate dehydrogenase - Cucumis
sativus (Cucumber)
Length = 382
Score = 47.2 bits (107), Expect = 5e-04
Identities = 32/99 (32%), Positives = 47/99 (47%), Gaps = 3/99 (3%)
Frame = +1
Query: 196 IATTTKAKISKEELLMEIPNHDALVVRSATQVTKEVLDAGVKL---KVVGRAGAGVDNID 366
I T K +S E++L I + V+ T+ EVL + + K G +N+D
Sbjct: 42 ICTEKKTILSVEDILALIGDKCDGVIGQLTEDWGEVLFSALSRAGGKAFSNMAVGYNNVD 101
Query: 367 VXSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVQ 483
V +A K GV V N PG + EL +L L AR +V+
Sbjct: 102 VNAANKYGVAVGNTPGVLTETTAELAASLSLAAARRIVE 140
>UniRef50_Q89J71 Cluster: 2-hydroxyacid dehydrogenase; n=8;
Bradyrhizobiaceae|Rep: 2-hydroxyacid dehydrogenase -
Bradyrhizobium japonicum
Length = 317
Score = 46.8 bits (106), Expect = 7e-04
Identities = 22/73 (30%), Positives = 38/73 (52%)
Frame = +1
Query: 262 ALVVRSATQVTKEVLDAGVKLKVVGRAGAGVDNIDVXSAGKKGVGVINAPGANALSACEL 441
A++ T + E +D L + G G D +D+ +A + + V ++PGANA S ++
Sbjct: 47 AMLTGGGTPLGAEAMDLFPNLGAIVCYGTGYDGVDLKAAAARDIAVGHSPGANAASVADI 106
Query: 442 TCTLMLVLARHVV 480
TLML R ++
Sbjct: 107 AMTLMLATTRRIL 119
Database: uniref50
Posted date: Oct 5, 2007 11:19 AM
Number of letters in database: 575,637,011
Number of sequences in database: 1,657,284
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 716,402,134
Number of Sequences: 1657284
Number of extensions: 13049111
Number of successful extensions: 51162
Number of sequences better than 10.0: 500
Number of HSP's better than 10.0 without gapping: 45828
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 50736
length of database: 575,637,011
effective HSP length: 100
effective length of database: 409,908,611
effective search space used: 76652910257
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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