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Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= MFBP03_F_L16
         (866 letters)

Database: uniref50 
           1,657,284 sequences; 575,637,011 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

UniRef50_Q16GI7 Cluster: Chromaffin granule amine transporter, p...   195   1e-48
UniRef50_Q94243 Cluster: Putative uncharacterized protein; n=4; ...   131   2e-29
UniRef50_Q6NT16 Cluster: Uncharacterized MFS-type transporter C6...   131   2e-29
UniRef50_UPI0000E45EC3 Cluster: PREDICTED: hypothetical protein;...   101   2e-20
UniRef50_A7SKG1 Cluster: Predicted protein; n=1; Nematostella ve...   100   1e-19
UniRef50_UPI0000587124 Cluster: PREDICTED: similar to ENSANGP000...    95   2e-18
UniRef50_A7SKG0 Cluster: Predicted protein; n=1; Nematostella ve...    90   8e-17
UniRef50_UPI0000E46072 Cluster: PREDICTED: similar to ENSANGP000...    73   1e-11
UniRef50_UPI0000D56173 Cluster: PREDICTED: similar to F55A4.8a; ...    63   1e-08
UniRef50_A0BV72 Cluster: Chromosome undetermined scaffold_13, wh...    63   1e-08
UniRef50_A0BEN4 Cluster: Chromosome undetermined scaffold_102, w...    62   1e-08
UniRef50_A0DCT4 Cluster: Chromosome undetermined scaffold_46, wh...    60   7e-08
UniRef50_A0BTR5 Cluster: Chromosome undetermined scaffold_128, w...    60   7e-08
UniRef50_UPI000065FBE2 Cluster: OTTHUMP00000017233.; n=1; Takifu...    59   1e-07
UniRef50_UPI0000D56172 Cluster: PREDICTED: similar to CG6850-PA;...    58   4e-07
UniRef50_A0EF24 Cluster: Chromosome undetermined scaffold_92, wh...    55   2e-06
UniRef50_A7SMH9 Cluster: Predicted protein; n=1; Nematostella ve...    54   5e-06
UniRef50_UPI00006CD2E9 Cluster: Major Facilitator Superfamily pr...    48   4e-04
UniRef50_UPI000150A26C Cluster: hypothetical protein TTHERM_0028...    46   0.001
UniRef50_A4HMU9 Cluster: Putative uncharacterized protein; n=3; ...    44   0.004
UniRef50_Q0W1D9 Cluster: Permease; n=1; uncultured methanogenic ...    44   0.007
UniRef50_UPI00006CCA75 Cluster: Major Facilitator Superfamily pr...    42   0.015
UniRef50_Q0W0C7 Cluster: Putative permease; n=1; uncultured meth...    42   0.020
UniRef50_A6T4B1 Cluster: Transporter of the MFS superfamily; n=1...    42   0.027
UniRef50_A0CJH2 Cluster: Chromosome undetermined scaffold_2, who...    42   0.027
UniRef50_Q5N0B7 Cluster: Multidrug-efflux transporter quinolene ...    41   0.035
UniRef50_Q0TPZ9 Cluster: Transporter, major facilitator family; ...    40   0.082
UniRef50_Q97D15 Cluster: MDR-type permease; n=10; Clostridium|Re...    40   0.11 
UniRef50_A6SJT0 Cluster: Putative uncharacterized protein; n=1; ...    40   0.11 
UniRef50_A5V1Q7 Cluster: Major facilitator superfamily MFS_1; n=...    39   0.14 
UniRef50_A7SHR0 Cluster: Predicted protein; n=1; Nematostella ve...    39   0.14 
UniRef50_A7F8H5 Cluster: Putative uncharacterized protein; n=1; ...    39   0.14 
UniRef50_Q7UXZ3 Cluster: Tetracycline-efflux transporter; n=1; P...    38   0.25 
UniRef50_Q03CN7 Cluster: Permease of the major facilitator super...    38   0.25 
UniRef50_Q74D39 Cluster: Drug resistance transporter, EmrB/QacA ...    38   0.44 
UniRef50_Q6L134 Cluster: Resistance protein; n=1; Picrophilus to...    38   0.44 
UniRef50_Q4DHV4 Cluster: Putative uncharacterized protein; n=2; ...    37   0.76 
UniRef50_Q8NRB5 Cluster: Permeases of the major facilitator supe...    36   1.3  
UniRef50_Q18V64 Cluster: Major facilitator superfamily MFS_1; n=...    36   1.3  
UniRef50_A5FA66 Cluster: Drug resistance transporter, EmrB/QacA ...    36   1.3  
UniRef50_A4L2N9 Cluster: Permease; n=10; Lactobacillus|Rep: Perm...    36   1.3  
UniRef50_Q6MQ30 Cluster: Tetracycline-efflux transporter; n=1; B...    36   1.8  
UniRef50_A4VC93 Cluster: Permease of the major facilitator super...    36   1.8  
UniRef50_Q4Q5T8 Cluster: Putative uncharacterized protein; n=3; ...    36   1.8  
UniRef50_Q5TBJ2 Cluster: OTTHUMP00000017233; n=1; Homo sapiens|R...    36   1.8  
UniRef50_Q39KV2 Cluster: Major facilitator superfamily (MFS_1) t...    35   2.3  
UniRef50_O31131 Cluster: Putative efflux protein; n=1; Brevibact...    35   2.3  
UniRef50_A7I9X1 Cluster: Major facilitator superfamily MFS_1; n=...    35   2.3  
UniRef50_A2SRS3 Cluster: Drug resistance transporter, EmrB/QacA ...    35   2.3  
UniRef50_Q9RYR1 Cluster: Drug transport protein, putative; n=2; ...    35   3.1  
UniRef50_Q3BM88 Cluster: Drug:H+ antiporter-1 family protein; n=...    35   3.1  
UniRef50_A5FEH6 Cluster: Drug resistance transporter, EmrB/QacA ...    35   3.1  
UniRef50_Q4CUF8 Cluster: Putative uncharacterized protein; n=2; ...    35   3.1  
UniRef50_A0E3U2 Cluster: Chromosome undetermined scaffold_77, wh...    35   3.1  
UniRef50_Q8U4E5 Cluster: Quinolone resistance protein norA homol...    35   3.1  
UniRef50_Q5V1E4 Cluster: Transporter possibly hexose; n=5; Halob...    35   3.1  
UniRef50_Q9A8S0 Cluster: Tetracycline resistance protein; n=3; A...    34   4.1  
UniRef50_Q1GPE1 Cluster: Major facilitator superfamily MFS_1; n=...    34   4.1  
UniRef50_A6TX73 Cluster: Major facilitator superfamily MFS_1; n=...    34   4.1  
UniRef50_A3UH39 Cluster: Multidrug resistance protein, putative;...    34   4.1  
UniRef50_UPI000051033C Cluster: COG0477: Permeases of the major ...    34   5.4  
UniRef50_Q7U3D8 Cluster: Multidrug efflux transporter, MFS famil...    34   5.4  
UniRef50_Q04U94 Cluster: Permease; n=5; Bacteria|Rep: Permease -...    34   5.4  
UniRef50_A7H904 Cluster: Major facilitator superfamily MFS_1; n=...    34   5.4  
UniRef50_A5D3X1 Cluster: Xanthine/uracil permeases; n=1; Pelotom...    34   5.4  
UniRef50_Q9V3J5 Cluster: EG:BACR7A4.13 protein; n=1; Drosophila ...    34   5.4  
UniRef50_Q4UGZ5 Cluster: Putative uncharacterized protein; n=3; ...    34   5.4  
UniRef50_Q6KYT7 Cluster: Tetracycline resistance protein; n=1; P...    34   5.4  
UniRef50_UPI000050FAA6 Cluster: COG0477: Permeases of the major ...    33   7.1  
UniRef50_Q4ZRX5 Cluster: Major facilitator superfamily; n=3; Pse...    33   7.1  
UniRef50_Q4KGW4 Cluster: Drug transporter, putative; n=1; Pseudo...    33   7.1  
UniRef50_Q3IC21 Cluster: Putative lipoprotein component of a eff...    33   7.1  
UniRef50_Q8VKE2 Cluster: Drug transporter; n=18; Corynebacterine...    33   7.1  
UniRef50_A6LRB1 Cluster: Major facilitator superfamily MFS_1; n=...    33   7.1  
UniRef50_A0NKB5 Cluster: Permease, major facilitator superfamily...    33   7.1  
UniRef50_A0NID0 Cluster: Transporter protein; n=2; Lactobacillal...    33   7.1  
UniRef50_Q9HRX5 Cluster: Multidrug resistance protein homolog; n...    33   7.1  
UniRef50_Q8ZT99 Cluster: Antibiotic resistance (Efflux) protein,...    33   7.1  
UniRef50_Q5SJX2 Cluster: Multidrug resistance protein-related pr...    33   9.4  
UniRef50_Q1NQW5 Cluster: Major facilitator superfamily MFS_1; n=...    33   9.4  
UniRef50_Q0K446 Cluster: Putative MFS transporter; n=1; Ralstoni...    33   9.4  
UniRef50_A7IIB8 Cluster: Major facilitator superfamily MFS_1; n=...    33   9.4  
UniRef50_A6EDN7 Cluster: Drug resistance transporter EmrB/QacA s...    33   9.4  
UniRef50_A4T5I8 Cluster: Major facilitator superfamily MFS_1 pre...    33   9.4  
UniRef50_A3I9H4 Cluster: Probable multidrug efflux transporter; ...    33   9.4  

>UniRef50_Q16GI7 Cluster: Chromaffin granule amine transporter,
           putative; n=5; Endopterygota|Rep: Chromaffin granule
           amine transporter, putative - Aedes aegypti (Yellowfever
           mosquito)
          Length = 476

 Score =  195 bits (475), Expect = 1e-48
 Identities = 98/148 (66%), Positives = 108/148 (72%)
 Frame = +3

Query: 273 AEKKGCTATEYXXXXXXXXXXXXXXSPIYGAHLNRIGPKLLFNTGILTTGTCAILFGLLD 452
           AE+KG TATEY              SPIYG  +NRIGPK+LFN+GI TTGT AILFGLLD
Sbjct: 1   AERKGATATEYGLVFGIFELVVFIISPIYGQCINRIGPKVLFNSGIFTTGTSAILFGLLD 60

Query: 453 RVXGHVPFITLSFVIRIVEAMGNAAFLTASFAIIAKEFPNNVATMFASIETFFGLGLIVG 632
           R+  H+PFIT +F+IRIVEA+GNAAFLTASFAIIAKEFPNNVAT FAS+ET FGLGLIVG
Sbjct: 61  RIPDHIPFITCAFIIRIVEALGNAAFLTASFAIIAKEFPNNVATTFASLETCFGLGLIVG 120

Query: 633 PTXXXXXXXXXXXSLPFAVLGSALFCXA 716
           P             LPF VLGSALF  A
Sbjct: 121 PMVGGALYSVGGYYLPFVVLGSALFVTA 148


>UniRef50_Q94243 Cluster: Putative uncharacterized protein; n=4;
           Caenorhabditis|Rep: Putative uncharacterized protein -
           Caenorhabditis elegans
          Length = 626

 Score =  131 bits (317), Expect = 2e-29
 Identities = 70/176 (39%), Positives = 97/176 (55%)
 Frame = +3

Query: 177 SKRQWLTIVVIGIADFCNAICVALQAPFYPKEAEKKGCTATEYXXXXXXXXXXXXXXSPI 356
           S RQ L+I ++ +A+ C+ I  +  APFYP EA+ K  + T+               SP+
Sbjct: 220 SSRQLLSISMLSLANLCSTIAFSCIAPFYPAEAKLKNLSETQTGIVFGIFEFTMFIISPL 279

Query: 357 YGAHLNRIGPKLLFNTGILTTGTCAILFGLLDRVXGHVPFITLSFVIRIVEAMGNAAFLT 536
           +G ++  IG + +F  GI  TG  AILFG L+ +     F   S ++RI+EA+G+AAF+T
Sbjct: 280 FGKYIIFIGARTMFIVGIAVTGVTAILFGFLNFLPSGNTFFWFSVLVRILEAVGDAAFVT 339

Query: 537 ASFAIIAKEFPNNVATMFASIETFFGLGLIVGPTXXXXXXXXXXXSLPFAVLGSAL 704
           +SFAI AK FP NVA +   +ETF GLG   GP             LPF VLG  L
Sbjct: 340 SSFAIAAKSFPKNVAFVVGILETFAGLGYTAGPVIGGFFYDIGGFQLPFLVLGIVL 395


>UniRef50_Q6NT16 Cluster: Uncharacterized MFS-type transporter
           C6orf192; n=22; Euteleostomi|Rep: Uncharacterized
           MFS-type transporter C6orf192 - Homo sapiens (Human)
          Length = 456

 Score =  131 bits (317), Expect = 2e-29
 Identities = 68/187 (36%), Positives = 102/187 (54%)
 Frame = +3

Query: 177 SKRQWLTIVVIGIADFCNAICVALQAPFYPKEAEKKGCTATEYXXXXXXXXXXXXXXSPI 356
           S+ Q   ++     +  + +C ++  PF+PKEAEKKG + T                S +
Sbjct: 30  SREQVFVLISAASVNLGSMMCYSILGPFFPKEAEKKGASNTIIGMIFGCFALFELLASLV 89

Query: 357 YGAHLNRIGPKLLFNTGILTTGTCAILFGLLDRVXGHVPFITLSFVIRIVEAMGNAAFLT 536
           +G +L  IG K +F  G+  +G   ILFG+LDRV     FI + F++R+++A+  AA +T
Sbjct: 90  FGNYLVHIGAKFMFVAGMFVSGGVTILFGVLDRVPDGPVFIAMCFLVRVMDAVSFAAAMT 149

Query: 537 ASFAIIAKEFPNNVATMFASIETFFGLGLIVGPTXXXXXXXXXXXSLPFAVLGSALFCXA 716
           AS +I+AK FPNNVAT+  S+ETF GLGLI+GP             +PF VLG  +    
Sbjct: 150 ASSSILAKAFPNNVATVLGSLETFSGLGLILGPPVGGFLYQSFGYEVPFIVLGCVVLLMV 209

Query: 717 GYELFPL 737
              ++ L
Sbjct: 210 PLNMYIL 216


>UniRef50_UPI0000E45EC3 Cluster: PREDICTED: hypothetical protein;
           n=1; Strongylocentrotus purpuratus|Rep: PREDICTED:
           hypothetical protein - Strongylocentrotus purpuratus
          Length = 244

 Score =  101 bits (242), Expect = 2e-20
 Identities = 57/137 (41%), Positives = 75/137 (54%)
 Frame = +3

Query: 186 QWLTIVVIGIADFCNAICVALQAPFYPKEAEKKGCTATEYXXXXXXXXXXXXXXSPIYGA 365
           Q LT V + I    + +  ++ APF+P EAEKKG + TE               SPI G 
Sbjct: 84  QKLTFVGMAIIYLASFMSFSVLAPFFPYEAEKKGVSPTETGLVFGIFALTSFIASPILGK 143

Query: 366 HLNRIGPKLLFNTGILTTGTCAILFGLLDRVXGHVPFITLSFVIRIVEAMGNAAFLTASF 545
           +L  IG K +F +G   T  C ILFG L+++ G   F+   FVIRIVEA+G+AA  TA  
Sbjct: 144 YLPTIGGKFMFLSGSFVTSGCNILFGFLNKIEGKTTFLIYCFVIRIVEALGSAATNTAGL 203

Query: 546 AIIAKEFPNNVATMFAS 596
           AI A  +P+ VA M  S
Sbjct: 204 AICANVYPDKVAQMSLS 220


>UniRef50_A7SKG1 Cluster: Predicted protein; n=1; Nematostella
           vectensis|Rep: Predicted protein - Nematostella
           vectensis
          Length = 487

 Score = 99.5 bits (237), Expect = 1e-19
 Identities = 54/187 (28%), Positives = 87/187 (46%)
 Frame = +3

Query: 177 SKRQWLTIVVIGIADFCNAICVALQAPFYPKEAEKKGCTATEYXXXXXXXXXXXXXXSPI 356
           S R+ L +V +    F +    ++ +PF+P EA  KG  +                 SP+
Sbjct: 41  STRRKLILVSLCFVYFSSCASFSILSPFFPNEAAIKGADSASIGIIFGVYSLVTFLMSPL 100

Query: 357 YGAHLNRIGPKLLFNTGILTTGTCAILFGLLDRVXGHVPFITLSFVIRIVEAMGNAAFLT 536
            G  L ++GP+ +  +G+   G    LFG +  +     FI    ++RIV A+G +    
Sbjct: 101 MGIWLPKVGPRFMITSGLFLMGGAETLFGFVADMPNGSVFIVFCILLRIVSALGGSMADV 160

Query: 537 ASFAIIAKEFPNNVATMFASIETFFGLGLIVGPTXXXXXXXXXXXSLPFAVLGSALFCXA 716
           A FAI+A EFPN++  +  S+E F GLG + GP             LPF V+G+++    
Sbjct: 161 AIFAIVAGEFPNSIGAVTGSMEVFSGLGFMAGPPLGGVLFTAGGFRLPFIVMGASILLSL 220

Query: 717 GYELFPL 737
              +F L
Sbjct: 221 PLVMFVL 227


>UniRef50_UPI0000587124 Cluster: PREDICTED: similar to
           ENSANGP00000018482; n=1; Strongylocentrotus
           purpuratus|Rep: PREDICTED: similar to ENSANGP00000018482
           - Strongylocentrotus purpuratus
          Length = 376

 Score = 95.5 bits (227), Expect = 2e-18
 Identities = 53/178 (29%), Positives = 85/178 (47%), Gaps = 2/178 (1%)
 Frame = +3

Query: 168 FDFSKRQWLTIVVIGIADFCNAICVALQAPFYPKEAEKKGCTATEYXXXXXXXXXXXXXX 347
           +  +K   +T + + ++ F + +  ++ APF+P EA ++G    E               
Sbjct: 89  YKITKSDIITFLCLVVSTFISWLAFSIMAPFFPNEAHRRGLMDIEVGIIFSLQALTSTIV 148

Query: 348 SPIYGAHLNRIGPKLLFNTGILTTGTCAILFGLLDRVXGHVPFITLSFVIRIVEAMGNAA 527
           SPI G  +  IG K+   TG+    T  ILFG   ++     FI  +++ RI+  +G   
Sbjct: 149 SPIVGKFIPLIGAKVTLVTGLFLEATGNILFGYCVKLHSKTAFIAFAYITRILVGLGVGT 208

Query: 528 FLTASFAIIAKEFPNNVATMFASIETFFGLGLIVGPTXXXXXXXXXXXS--LPFAVLG 695
            +TA+  I AK FPN++A     +ET  GLGL++GP            S  LPF V+G
Sbjct: 209 SVTATMTINAKTFPNHIARTMGLLETTAGLGLLLGPVFGGLLYQLGGSSYLLPFVVIG 266


>UniRef50_A7SKG0 Cluster: Predicted protein; n=1; Nematostella
           vectensis|Rep: Predicted protein - Nematostella
           vectensis
          Length = 387

 Score = 89.8 bits (213), Expect = 8e-17
 Identities = 51/176 (28%), Positives = 83/176 (47%), Gaps = 1/176 (0%)
 Frame = +3

Query: 183 RQWLTIVVIGIADFCNAICVALQAPFYPKEAEKKGCTATEYXXXXXXXXXXXXXXSPIYG 362
           R+    +++ +  F    C++L + F+  EA+KKG   T                + +YG
Sbjct: 60  RRVFIFLLLSLVYFLTYACLSLMSAFFTIEAQKKGVNNTVIGFIFGMYPLMAFFSALMYG 119

Query: 363 AHLN-RIGPKLLFNTGILTTGTCAILFGLLDRVXGHVPFITLSFVIRIVEAMGNAAFLTA 539
           A L  + GP  +  TG++  G    LF  ++ +     +I   F+IR V A G +A   A
Sbjct: 120 AWLMPQWGPNFVLLTGLVLNGGAHFLFAYVENLPSGAVYILFCFLIRTVSAFGGSACENA 179

Query: 540 SFAIIAKEFPNNVATMFASIETFFGLGLIVGPTXXXXXXXXXXXSLPFAVLGSALF 707
             AI+  EFP NV+ + +++E F G+   +GP             LPF V+G+ALF
Sbjct: 180 VLAILIGEFPENVSAIVSALEIFAGISFALGPVAGGGLYTVGGFKLPFLVMGAALF 235


>UniRef50_UPI0000E46072 Cluster: PREDICTED: similar to
           ENSANGP00000018482, partial; n=1; Strongylocentrotus
           purpuratus|Rep: PREDICTED: similar to
           ENSANGP00000018482, partial - Strongylocentrotus
           purpuratus
          Length = 185

 Score = 72.5 bits (170), Expect = 1e-11
 Identities = 37/84 (44%), Positives = 47/84 (55%)
 Frame = +3

Query: 444 LLDRVXGHVPFITLSFVIRIVEAMGNAAFLTASFAIIAKEFPNNVATMFASIETFFGLGL 623
           +LDR+     F+T  FVIR VEA+G+AA LTA  AI +  +P NVA +   +E F GLG 
Sbjct: 1   VLDRIDDKTMFLTYCFVIRTVEALGSAATLTAGMAICSNVYPENVAQVNGFLELFLGLGF 60

Query: 624 IVGPTXXXXXXXXXXXSLPFAVLG 695
            +GP             LPF VLG
Sbjct: 61  AIGPPLGSLFYGIGGYELPFIVLG 84


>UniRef50_UPI0000D56173 Cluster: PREDICTED: similar to F55A4.8a;
           n=1; Tribolium castaneum|Rep: PREDICTED: similar to
           F55A4.8a - Tribolium castaneum
          Length = 445

 Score = 62.9 bits (146), Expect = 1e-08
 Identities = 31/74 (41%), Positives = 44/74 (59%)
 Frame = +3

Query: 414 TTGTCAILFGLLDRVXGHVPFITLSFVIRIVEAMGNAAFLTASFAIIAKEFPNNVATMFA 593
           T G    + G L  +  +  F T SF+IR +EA+G +A+ TAS+ II   FP+N   +  
Sbjct: 69  TKGMSESMAGTLHIIDNYALFTTFSFLIRGLEALGASAYSTASYVIIVNIFPDNAGAVRG 128

Query: 594 SIETFFGLGLIVGP 635
            +ETF GLG+ VGP
Sbjct: 129 LLETFVGLGMSVGP 142



 Score = 35.9 bits (79), Expect = 1.3
 Identities = 14/38 (36%), Positives = 25/38 (65%)
 Frame = +3

Query: 174 FSKRQWLTIVVIGIADFCNAICVALQAPFYPKEAEKKG 287
           F+ +Q + +V++   DF +   +++ APFYP+EA  KG
Sbjct: 34  FTCKQKVALVMLATVDFMSFCSMSIMAPFYPQEAATKG 71


>UniRef50_A0BV72 Cluster: Chromosome undetermined scaffold_13, whole
           genome shotgun sequence; n=1; Paramecium
           tetraurelia|Rep: Chromosome undetermined scaffold_13,
           whole genome shotgun sequence - Paramecium tetraurelia
          Length = 485

 Score = 62.9 bits (146), Expect = 1e-08
 Identities = 45/164 (27%), Positives = 74/164 (45%), Gaps = 2/164 (1%)
 Frame = +3

Query: 222 FCNAICVALQAPFYPKEAEKKG-CTATEYXXXXXXXXXXXXXXSPIYGAHLNRIGPKLLF 398
           F NA  V++ APFYP  A++K   + +                S + G  ++  G +   
Sbjct: 41  FLNA-AVSVIAPFYPPLAKEKAHVSVSTIGYIFGLNPIGAFFFSLVMGKKMSHWGRRRCM 99

Query: 399 NTGILTTGTCAILFGLLDRVXGHVP-FITLSFVIRIVEAMGNAAFLTASFAIIAKEFPNN 575
             G++      + FGLLD +  +   F+T+S V R ++    AA+ + SFA I   +P++
Sbjct: 100 LLGLVIQSAVVVAFGLLDFMTFNKELFVTVSCVTRFLQGASRAAYSSISFAYIPILWPDS 159

Query: 576 VATMFASIETFFGLGLIVGPTXXXXXXXXXXXSLPFAVLGSALF 707
           +    + +ET  GLGL+ GP             + F VLG   F
Sbjct: 160 IQKKISILETLTGLGLMSGPFIGAALDALFGYQMIFYVLGGIFF 203


>UniRef50_A0BEN4 Cluster: Chromosome undetermined scaffold_102,
           whole genome shotgun sequence; n=3; Paramecium
           tetraurelia|Rep: Chromosome undetermined scaffold_102,
           whole genome shotgun sequence - Paramecium tetraurelia
          Length = 441

 Score = 62.5 bits (145), Expect = 1e-08
 Identities = 46/160 (28%), Positives = 62/160 (38%), Gaps = 3/160 (1%)
 Frame = +3

Query: 228 NAIC---VALQAPFYPKEAEKKGCTATEYXXXXXXXXXXXXXXSPIYGAHLNRIGPKLLF 398
           N IC   ++L APFYP  A K     +                S I G  LN      L 
Sbjct: 14  NLICTLGLSLIAPFYPTYALKFDVKGSLLGLIFGINPIGGMLSSLIVGKILNNKNQTTLL 73

Query: 399 NTGILTTGTCAILFGLLDRVXGHVPFITLSFVIRIVEAMGNAAFLTASFAIIAKEFPNNV 578
           + G+L        F LL        FIT+S + R +   G +AFLT  +A I +++P +V
Sbjct: 74  SLGMLIQSIGLFCFPLLTLTNDRTMFITISLLGRFISGFGASAFLTPLYAAIPQKYPESV 133

Query: 579 ATMFASIETFFGLGLIVGPTXXXXXXXXXXXSLPFAVLGS 698
               A  E F   G + GP            S PF +  S
Sbjct: 134 DQKMAIAEFFSSFGYLCGPVIGSLLYTLGGFSFPFILFAS 173


>UniRef50_A0DCT4 Cluster: Chromosome undetermined scaffold_46, whole
           genome shotgun sequence; n=2; Paramecium
           tetraurelia|Rep: Chromosome undetermined scaffold_46,
           whole genome shotgun sequence - Paramecium tetraurelia
          Length = 530

 Score = 60.1 bits (139), Expect = 7e-08
 Identities = 41/168 (24%), Positives = 70/168 (41%), Gaps = 2/168 (1%)
 Frame = +3

Query: 213 IADFCNAICVALQAPFYPK-EAEKKGCTATEYXXXXXXXXXXXXXXSPIYGAHLNRIGPK 389
           I +F   + ++  APFYP   A+K G T ++               S + G+ +   G K
Sbjct: 48  ITNFVINVGISQIAPFYPGLAADKAGLTYSQIGLVFSINPLGSILFSFVIGSFIQVWGRK 107

Query: 390 LLFNTGILTTGTCAILFGLLDRVXGHVP-FITLSFVIRIVEAMGNAAFLTASFAIIAKEF 566
                 ++   +  ILFG L+ +  +   F ++S + R  + M  + + T +FA +   +
Sbjct: 108 KCLMIALVVQSSVQILFGCLNFMTDNKALFFSMSLISRFFQGMSRSVYSTVTFAYVPIFW 167

Query: 567 PNNVATMFASIETFFGLGLIVGPTXXXXXXXXXXXSLPFAVLGSALFC 710
           P       A +ET   LGL+ GP            S+PF V+     C
Sbjct: 168 PGEFQKKLAIMETMTALGLLFGPMIGSVLNYAFGYSIPFFVIAIFFLC 215


>UniRef50_A0BTR5 Cluster: Chromosome undetermined scaffold_128,
           whole genome shotgun sequence; n=1; Paramecium
           tetraurelia|Rep: Chromosome undetermined scaffold_128,
           whole genome shotgun sequence - Paramecium tetraurelia
          Length = 423

 Score = 60.1 bits (139), Expect = 7e-08
 Identities = 43/171 (25%), Positives = 62/171 (36%)
 Frame = +3

Query: 234 ICVALQAPFYPKEAEKKGCTATEYXXXXXXXXXXXXXXSPIYGAHLNRIGPKLLFNTGIL 413
           +C +L  PF+P  A+KKG + T                S I    LN          G+L
Sbjct: 1   MCGSLITPFFPPYADKKGISQTTLGLIIAAGPFGGLLASIIIAKTLNHRNRNKYILIGVL 60

Query: 414 TTGTCAILFGLLDRVXGHVPFITLSFVIRIVEAMGNAAFLTASFAIIAKEFPNNVATMFA 593
                 + F L D     VP I ++ + R +  +G + FLT  F  I   +P +V    +
Sbjct: 61  GEPLSLLFFSLTDLFEDKVPIIIIASIGRFIGGIGTSLFLTPFFGYIPILYPKDVEKKVS 120

Query: 594 SIETFFGLGLIVGPTXXXXXXXXXXXSLPFAVLGSALFCXAGYELFPLTSI 746
             E F  +G   GP              PF V  S  F    +    L S+
Sbjct: 121 ISEAFSSVGFFAGPALGSALYALGGYLTPFLVFSSFGFLSLPFLYAALQSV 171


>UniRef50_UPI000065FBE2 Cluster: OTTHUMP00000017233.; n=1; Takifugu
           rubripes|Rep: OTTHUMP00000017233. - Takifugu rubripes
          Length = 304

 Score = 59.3 bits (137), Expect = 1e-07
 Identities = 29/89 (32%), Positives = 45/89 (50%)
 Frame = +3

Query: 177 SKRQWLTIVVIGIADFCNAICVALQAPFYPKEAEKKGCTATEYXXXXXXXXXXXXXXSPI 356
           +KRQ LT++ I   +F + IC ++  PF+P EA KKG + T                + I
Sbjct: 5   TKRQILTLISIASVNFSSMICYSILGPFFPNEAVKKGASQTVIGLIFGCYAICNLLGALI 64

Query: 357 YGAHLNRIGPKLLFNTGILTTGTCAILFG 443
            G ++ +IG K +   G+  +  C ILFG
Sbjct: 65  LGKYIVQIGAKFMLVMGLYVSSVCTILFG 93


>UniRef50_UPI0000D56172 Cluster: PREDICTED: similar to CG6850-PA;
           n=3; Endopterygota|Rep: PREDICTED: similar to CG6850-PA
           - Tribolium castaneum
          Length = 1609

 Score = 57.6 bits (133), Expect = 4e-07
 Identities = 27/67 (40%), Positives = 38/67 (56%)
 Frame = +3

Query: 435 LFGLLDRVXGHVPFITLSFVIRIVEAMGNAAFLTASFAIIAKEFPNNVATMFASIETFFG 614
           L   L+ V  +  F T   VIR  EA+G +AF TAS+  +   FP N+ ++   +ETF G
Sbjct: 55  LLRTLEYVKNYTLFTTCCIVIRGFEALGASAFSTASYVFVVNTFPQNIGSVLGILETFVG 114

Query: 615 LGLIVGP 635
           LG+  GP
Sbjct: 115 LGMSTGP 121


>UniRef50_A0EF24 Cluster: Chromosome undetermined scaffold_92, whole
           genome shotgun sequence; n=2; Paramecium
           tetraurelia|Rep: Chromosome undetermined scaffold_92,
           whole genome shotgun sequence - Paramecium tetraurelia
          Length = 446

 Score = 55.2 bits (127), Expect = 2e-06
 Identities = 38/176 (21%), Positives = 70/176 (39%)
 Frame = +3

Query: 180 KRQWLTIVVIGIADFCNAICVALQAPFYPKEAEKKGCTATEYXXXXXXXXXXXXXXSPIY 359
           K+  + I+++     CN + +++ APFYP+ A+ +  +                  S I 
Sbjct: 2   KQSQIFIILVSCNVVCN-LAMSIIAPFYPQFAKSRDISEDIIGIIFAAHPLGQFISSLIL 60

Query: 360 GAHLNRIGPKLLFNTGILTTGTCAILFGLLDRVXGHVPFITLSFVIRIVEAMGNAAFLTA 539
           G  +     + +   GI   G   ++FG L     +   +  SF+ R++  +G + F+T 
Sbjct: 61  GKVITHENRQKIMVIGISQQGLGLLMFGFLYYFESYWVVLLGSFLARLIGGIGASMFMTP 120

Query: 540 SFAIIAKEFPNNVATMFASIETFFGLGLIVGPTXXXXXXXXXXXSLPFAVLGSALF 707
            +A I + FP  +    A  E    +G + GP             LPF    +  F
Sbjct: 121 FYAFIPQLFPKQIEEKIAIAEVSTSIGFLAGPILGSALYQLGGFILPFFFFAACSF 176


>UniRef50_A7SMH9 Cluster: Predicted protein; n=1; Nematostella
           vectensis|Rep: Predicted protein - Nematostella
           vectensis
          Length = 494

 Score = 54.0 bits (124), Expect = 5e-06
 Identities = 36/145 (24%), Positives = 58/145 (40%), Gaps = 1/145 (0%)
 Frame = +3

Query: 273 AEKKGCTATEYXXXXXXXXXXXXXXSPIYGAHL-NRIGPKLLFNTGILTTGTCAILFGLL 449
           AE+ G ++T                 P  G +L  R GPK +   G++  G   + F   
Sbjct: 84  AEQHGVSSTVSGLIFGIYSLVAFMACPAIGTYLIPRFGPKAVLMCGLVVNGAAQLAFAFT 143

Query: 450 DRVXGHVPFITLSFVIRIVEAMGNAAFLTASFAIIAKEFPNNVATMFASIETFFGLGLIV 629
            R+     F  + F+IR + A+G AA   +  +I   +F ++V T+ + +E   GLG  V
Sbjct: 144 IRLPKGAVFAGICFLIRAISALGAAACENSVISITIGQFRSHVPTVMSVVEMSSGLGFTV 203

Query: 630 GPTXXXXXXXXXXXSLPFAVLGSAL 704
            P              PF  +   L
Sbjct: 204 APVLGGALFEIGGWKAPFLAVSCFL 228


>UniRef50_UPI00006CD2E9 Cluster: Major Facilitator Superfamily
           protein; n=1; Tetrahymena thermophila SB210|Rep: Major
           Facilitator Superfamily protein - Tetrahymena
           thermophila SB210
          Length = 614

 Score = 47.6 bits (108), Expect = 4e-04
 Identities = 35/129 (27%), Positives = 57/129 (44%), Gaps = 1/129 (0%)
 Frame = +3

Query: 252 APFYPKEAEKKGCTATEYXXXXXXXXXXXXXXSPIYGAHLNR-IGPKLLFNTGILTTGTC 428
           APF+P++A+  G   T                S I G  L++    K     GIL TG  
Sbjct: 23  APFFPQKAKTFGIDETMIGLIFSVHPVGNFICSLIIGKQLSKGENRKPATLLGILLTGIG 82

Query: 429 AILFGLLDRVXGHVPFITLSFVIRIVEAMGNAAFLTASFAIIAKEFPNNVATMFASIETF 608
            + F  +  +     FIT++ + RI+  +G + F T ++A I   + +        +E+ 
Sbjct: 83  ILGFATVQYITRKWVFITVTLLSRIILGVGQSLFSTPAYAYIPLLYKSTFEEKCGWMESV 142

Query: 609 FGLGLIVGP 635
            G GL+VGP
Sbjct: 143 CGFGLMVGP 151


>UniRef50_UPI000150A26C Cluster: hypothetical protein
           TTHERM_00283630; n=1; Tetrahymena thermophila SB210|Rep:
           hypothetical protein TTHERM_00283630 - Tetrahymena
           thermophila SB210
          Length = 292

 Score = 46.0 bits (104), Expect = 0.001
 Identities = 28/114 (24%), Positives = 45/114 (39%)
 Frame = +3

Query: 369 LNRIGPKLLFNTGILTTGTCAILFGLLDRVXGHVPFITLSFVIRIVEAMGNAAFLTASFA 548
           LN +G K +F  GI+        FG L  +     FI + F  R+++    AA  ++   
Sbjct: 2   LNLLGQKNVFCLGIIIQSISISTFGALYNLNDDAIFICICFFSRLIQGFSRAAISSSFVT 61

Query: 549 IIAKEFPNNVATMFASIETFFGLGLIVGPTXXXXXXXXXXXSLPFAVLGSALFC 710
            I + +P       + IE    LG ++GP             +PF +L     C
Sbjct: 62  YIPQIWPEEFQIKASLIERVGALGTLLGPGIGQVFYTFLGHQMPFYILSFIFLC 115


>UniRef50_A4HMU9 Cluster: Putative uncharacterized protein; n=3;
           Leishmania|Rep: Putative uncharacterized protein -
           Leishmania braziliensis
          Length = 648

 Score = 44.4 bits (100), Expect = 0.004
 Identities = 26/94 (27%), Positives = 42/94 (44%)
 Frame = +3

Query: 354 IYGAHLNRIGPKLLFNTGILTTGTCAILFGLLDRVXGHVPFITLSFVIRIVEAMGNAAFL 533
           ++G   +R+G K +   G+LT    +I FG+        P + L  + R ++   N   L
Sbjct: 71  LWGTASDRVGRKPIIQVGLLTNAIVSIFFGM-------SPSLKLCIITRFIQGCANGNVL 123

Query: 534 TASFAIIAKEFPNNVATMFASIETFFGLGLIVGP 635
            A   I            FA+I  F+G+G +VGP
Sbjct: 124 VAKTVIADITDKETEGMGFAAINIFWGVGSVVGP 157


>UniRef50_Q0W1D9 Cluster: Permease; n=1; uncultured methanogenic
           archaeon RC-I|Rep: Permease - Uncultured methanogenic
           archaeon RC-I
          Length = 410

 Score = 43.6 bits (98), Expect = 0.007
 Identities = 38/172 (22%), Positives = 65/172 (37%), Gaps = 1/172 (0%)
 Frame = +3

Query: 171 DFSKRQWLTIVVIGIADFCNAICVALQAPFYPKEAEKKGCTATEYXXXXXXXXXXXXXXS 350
           +  K Q L ++V+ IA F + +   +  P  P+ A   G +                  +
Sbjct: 10  NMDKNQKLALLVVFIAIFTDMLIYCMIVPILPEYASGLGASQQMIGLLFASYAITFLLAA 69

Query: 351 PIYGAHLNRIGPKLLFNTGILTTGTCAILFGLLDRVXGHVPFITLSFVIRIVEAMGNAAF 530
           P+ G   +R+G KL    G+L      +LF            +T+ FV R ++ +   A 
Sbjct: 70  PVVGVLSDRVGRKLPMLVGLLGLFGSTLLFAFSSD-------LTMLFVARALQGVSAGAT 122

Query: 531 LTASFAIIAKEFPNNVATMFASIETFFGL-GLIVGPTXXXXXXXXXXXSLPF 683
            TA  A+++  FP  +      I       G ++GP            +LPF
Sbjct: 123 WTAGLALLSDLFPPKMRQQAIGIGISGSFAGTLLGPLFGGALYEYGGYALPF 174


>UniRef50_UPI00006CCA75 Cluster: Major Facilitator Superfamily
           protein; n=1; Tetrahymena thermophila SB210|Rep: Major
           Facilitator Superfamily protein - Tetrahymena
           thermophila SB210
          Length = 526

 Score = 42.3 bits (95), Expect = 0.015
 Identities = 40/167 (23%), Positives = 66/167 (39%), Gaps = 1/167 (0%)
 Frame = +3

Query: 201 VVIGIADFCNAICVALQAPFYPKEAEKKGCTATEYXXXXXXXXXXXXXXSPIYGAHLNRI 380
           ++I I  F  +  + +  PF+P  A+K+G                    S +    L+ +
Sbjct: 47  ILIAIC-FLQSASITMIVPFFPPLAKKQGTPLILKGLVLGINPIGSFVYSLVSSKMLSIL 105

Query: 381 GPKLLFNTGILTTGTCAILFGLLDRVXGHVPFITLSFVIRIVEAMGNAAFLTASFAI-IA 557
           G K LF  GI+        FG L  +     FI +    R+++    AA +T+SF + IA
Sbjct: 106 GQKKLFCLGIIFQSISISAFGALHHLDDDNIFINICIFSRLIQGFSRAA-VTSSFPVQIA 164

Query: 558 KEFPNNVATMFASIETFFGLGLIVGPTXXXXXXXXXXXSLPFAVLGS 698
           + +P         IE    LG ++GP             +PF  + S
Sbjct: 165 RMWP------LYLIERIAILGALLGPAIGQICYSFIGDFIPFYTISS 205


>UniRef50_Q0W0C7 Cluster: Putative permease; n=1; uncultured
           methanogenic archaeon RC-I|Rep: Putative permease -
           Uncultured methanogenic archaeon RC-I
          Length = 435

 Score = 41.9 bits (94), Expect = 0.020
 Identities = 39/166 (23%), Positives = 65/166 (39%), Gaps = 13/166 (7%)
 Frame = +3

Query: 177 SKRQWLTIVVIGIADFCNAICVALQAPFYPKEAEKKGCTATEYXXXXXXXXXXXXXXSPI 356
           SK +   I+V+ +  F   +   +  P  P  A   G TA +               +P+
Sbjct: 3   SKIKARQIIVLAVGMFIFTLGFGVIIPVMPYYANNLGATALDLGLLMATFSAMQFVCAPV 62

Query: 357 YGAHLNRIGPKLLFNTGILTTGTCAILFGL--------LDRVXGH----VPFITLSFVIR 500
           +GA  +RIG K +   G+   G    + GL        +  V GH     P I + F+  
Sbjct: 63  WGAISDRIGRKPVMMIGLTGFGLAFTVTGLSSEPAALAISEVIGHWTGLSPHIGVLFISE 122

Query: 501 IVEAMGNAAFLTASFAIIAK-EFPNNVATMFASIETFFGLGLIVGP 635
           ++    ++    A+ A IA    P     +   +    GLG+I+GP
Sbjct: 123 VIGGTLSSGIWPATLAFIADITKPEERGNLMGQMGAASGLGVIIGP 168


>UniRef50_A6T4B1 Cluster: Transporter of the MFS superfamily; n=1;
           Janthinobacterium sp. Marseille|Rep: Transporter of the
           MFS superfamily - Janthinobacterium sp. (strain
           Marseille) (Minibacterium massiliensis)
          Length = 402

 Score = 41.5 bits (93), Expect = 0.027
 Identities = 23/68 (33%), Positives = 32/68 (47%)
 Frame = +3

Query: 498 RIVEAMGNAAFLTASFAIIAKEFPNNVATMFASIETFFGLGLIVGPTXXXXXXXXXXXSL 677
           R V  +G A  LTA  AI    F N+ A   +S+   FG+G I+GP             +
Sbjct: 104 RFVSGLGEAMQLTALLAIGTTYFFNHRAVAASSLNFTFGIGAIIGPNLGAAILNSTHWQM 163

Query: 678 PFAVLGSA 701
           PF V G++
Sbjct: 164 PFMVFGAS 171


>UniRef50_A0CJH2 Cluster: Chromosome undetermined scaffold_2, whole
           genome shotgun sequence; n=1; Paramecium
           tetraurelia|Rep: Chromosome undetermined scaffold_2,
           whole genome shotgun sequence - Paramecium tetraurelia
          Length = 418

 Score = 41.5 bits (93), Expect = 0.027
 Identities = 36/156 (23%), Positives = 62/156 (39%)
 Frame = +3

Query: 216 ADFCNAICVALQAPFYPKEAEKKGCTATEYXXXXXXXXXXXXXXSPIYGAHLNRIGPKLL 395
           A+F     +AL APF+P  A ++G + T                S   G  LN    +++
Sbjct: 15  ANFIICASMALIAPFFPPFAFEQGLSKTLVGIIVALHPLGGIFGSIKIGEVLNDKNRQIM 74

Query: 396 FNTGILTTGTCAILFGLLDRVXGHVPFITLSFVIRIVEAMGNAAFLTASFAIIAKEFPNN 575
               ++    C  LF L+  +  +  +IT   +I +V  +  + F+T+ ++ I   FP  
Sbjct: 75  LTGSMIVQAICLFLFILIYLIKTYW-YIT---IISLVSRVAYSVFITSFYSYIPFLFPEE 130

Query: 576 VATMFASIETFFGLGLIVGPTXXXXXXXXXXXSLPF 683
                A  E    LG ++GP            + PF
Sbjct: 131 HEQKIALAEAASALGYMLGPMIGSLLYSIGGFTFPF 166


>UniRef50_Q5N0B7 Cluster: Multidrug-efflux transporter quinolene
           resistance protein NorA; n=2; Synechococcus
           elongatus|Rep: Multidrug-efflux transporter quinolene
           resistance protein NorA - Synechococcus sp. (strain ATCC
           27144 / PCC 6301 / SAUG 1402/1)(Anacystis nidulans)
          Length = 403

 Score = 41.1 bits (92), Expect = 0.035
 Identities = 38/152 (25%), Positives = 57/152 (37%), Gaps = 1/152 (0%)
 Frame = +3

Query: 183 RQWLTIVVIGIADFCNAICVALQAPFYPKEAEKKGCTATEYXXXXXXXXXXXXXXSPIYG 362
           RQ L    + +  F +A+ V L  P  P+     G  A                 +P+ G
Sbjct: 10  RQRLAFFSVALNVFMDALGVTLLLPILPELLRPFGSNAFLLGAFASVYTLAQFISTPVLG 69

Query: 363 AHLNRIGPKLLFNTGILTTGTCAILFGLLDRVXGHVPFITLSFVIRIVEAMGNAAFLTAS 542
           +  +R G +      ++ TG   +L      V   V  + L F  RI+  +    F  A 
Sbjct: 70  SLSDRFGRRPPLILTLVFTGLAYVLLA----VGSLVENLPLLFAARILAGLAGGVFAIAQ 125

Query: 543 FAIIAKEF-PNNVATMFASIETFFGLGLIVGP 635
             I  +E  P   +T F  I   FGLG + GP
Sbjct: 126 AYIADRESDPLKRSTQFGWIGAAFGLGFLFGP 157


>UniRef50_Q0TPZ9 Cluster: Transporter, major facilitator family;
           n=3; Clostridium perfringens|Rep: Transporter, major
           facilitator family - Clostridium perfringens (strain
           ATCC 13124 / NCTC 8237 / Type A)
          Length = 566

 Score = 39.9 bits (89), Expect = 0.082
 Identities = 26/97 (26%), Positives = 45/97 (46%), Gaps = 1/97 (1%)
 Frame = +3

Query: 351 PIYGAHLNRIGPKLLFNTGILTTGTCAILFGLLDRVXGHVPFITLSFVIRIVEAMGNAAF 530
           P+ G   ++ G K ++   I   G  ++L G+ D V  +  F+  S   R++EA+G    
Sbjct: 61  PLMGKLSDKYGRKKVYMVSITLFGLGSLLCGVSDYVNSYT-FLLFS---RVIEAIGGGGI 116

Query: 531 LTASFAIIAKEFP-NNVATMFASIETFFGLGLIVGPT 638
           +  + A I   FP     +    I   +G+  +VGPT
Sbjct: 117 MPIATAYIGTSFPVEKRGSALGMIGGVYGIATVVGPT 153


>UniRef50_Q97D15 Cluster: MDR-type permease; n=10; Clostridium|Rep:
           MDR-type permease - Clostridium acetobutylicum
          Length = 486

 Score = 39.5 bits (88), Expect = 0.11
 Identities = 22/69 (31%), Positives = 35/69 (50%), Gaps = 1/69 (1%)
 Frame = +3

Query: 432 ILFGLLDRVXGHVPFITLSFVIRIVEAMGNAAFLTASFAIIAKEFP-NNVATMFASIETF 608
           ILF L   + G    + +  V R+++A+G AA +  +  II + FP N        + TF
Sbjct: 87  ILFTLGSLLCGFTSSLVVLVVARVIQAIGAAATMATNQGIITQTFPPNERGRALGLLGTF 146

Query: 609 FGLGLIVGP 635
             LG ++GP
Sbjct: 147 VALGAMIGP 155


>UniRef50_A6SJT0 Cluster: Putative uncharacterized protein; n=1;
           Botryotinia fuckeliana B05.10|Rep: Putative
           uncharacterized protein - Botryotinia fuckeliana B05.10
          Length = 556

 Score = 39.5 bits (88), Expect = 0.11
 Identities = 22/68 (32%), Positives = 33/68 (48%), Gaps = 1/68 (1%)
 Frame = +3

Query: 435 LFGLLDRVXGHVPFITLSFVIRIVEAMGNAAFLTASFAIIAKEFPNNVATMF-ASIETFF 611
           LF +   + G  P      + R +  +G+A  LT SF ++A   P     +F A++   F
Sbjct: 131 LFEIGSLICGVAPNSLTLIIGRAIAGVGSAGILTGSFVVVAHSVPIQRRPVFTAAVGLMF 190

Query: 612 GLGLIVGP 635
           GLG  VGP
Sbjct: 191 GLGATVGP 198


>UniRef50_A5V1Q7 Cluster: Major facilitator superfamily MFS_1; n=4;
           Chloroflexaceae|Rep: Major facilitator superfamily MFS_1
           - Roseiflexus sp. RS-1
          Length = 428

 Score = 39.1 bits (87), Expect = 0.14
 Identities = 25/98 (25%), Positives = 44/98 (44%), Gaps = 2/98 (2%)
 Frame = +3

Query: 348 SPIYGAHLNRIGPKLLFNTGILTTGTCAILFGLLDRVX--GHVPFITLSFVIRIVEAMGN 521
           +P+ GA  +R G + +    +L +G   +LFG  + +   G    + + F+ R++  +  
Sbjct: 66  TPVLGALSDRYGRRPILLISVLGSGLSYVLFGFAEYLSFLGVETVLAILFIGRMLSGITG 125

Query: 522 AAFLTASFAIIAKEFPNNVATMFASIETFFGLGLIVGP 635
           A+  TA   I     P         I   FGLG ++GP
Sbjct: 126 ASISTAQAYIADTTTPEERTKGMGMIGAAFGLGFMLGP 163


>UniRef50_A7SHR0 Cluster: Predicted protein; n=1; Nematostella
           vectensis|Rep: Predicted protein - Nematostella
           vectensis
          Length = 145

 Score = 39.1 bits (87), Expect = 0.14
 Identities = 23/84 (27%), Positives = 35/84 (41%)
 Frame = +3

Query: 192 LTIVVIGIADFCNAICVALQAPFYPKEAEKKGCTATEYXXXXXXXXXXXXXXSPIYGAHL 371
           L +  + +  F N    ++ A F+P  A  +G   T+               S +YGA +
Sbjct: 62  LLLAEMSVVLFFNFASFSILATFFPNVALDRGADRTQIGLIFGAYPAIAFPASLVYGALI 121

Query: 372 NRIGPKLLFNTGILTTGTCAILFG 443
             IG + L   GI T G   +LFG
Sbjct: 122 PLIGTEKLLLAGIFTNGITVVLFG 145


>UniRef50_A7F8H5 Cluster: Putative uncharacterized protein; n=1;
           Sclerotinia sclerotiorum 1980|Rep: Putative
           uncharacterized protein - Sclerotinia sclerotiorum 1980
          Length = 882

 Score = 39.1 bits (87), Expect = 0.14
 Identities = 20/54 (37%), Positives = 32/54 (59%), Gaps = 2/54 (3%)
 Frame = +3

Query: 480 TLSFVI-RIVEAMGNAAFLTASFAIIAKEFPNNVATMF-ASIETFFGLGLIVGP 635
           +L+ +I R +  +G+A  LT SF ++A   P +   +F A++   FGLG  VGP
Sbjct: 471 SLTLIIGRAIAGVGSAGILTGSFVVVAHSVPMHKRPVFTAAVGLMFGLGATVGP 524


>UniRef50_Q7UXZ3 Cluster: Tetracycline-efflux transporter; n=1;
           Pirellula sp.|Rep: Tetracycline-efflux transporter -
           Rhodopirellula baltica
          Length = 500

 Score = 38.3 bits (85), Expect = 0.25
 Identities = 29/96 (30%), Positives = 42/96 (43%)
 Frame = +3

Query: 348 SPIYGAHLNRIGPKLLFNTGILTTGTCAILFGLLDRVXGHVPFITLSFVIRIVEAMGNAA 527
           +P+ GA  +R G + +    +   G   I+ GL        P +   FV RIV  +  A+
Sbjct: 119 APVLGALSDRFGRRPVILASLFGLGVDFIVTGL-------APTVGWLFVGRIVAGVMGAS 171

Query: 528 FLTASFAIIAKEFPNNVATMFASIETFFGLGLIVGP 635
           F TA+  I         A  F  +   FGLG I+GP
Sbjct: 172 FSTANAYIADVSTQETRARNFGLVGMMFGLGFIIGP 207


>UniRef50_Q03CN7 Cluster: Permease of the major facilitator
           superfamily; n=1; Lactobacillus casei ATCC 334|Rep:
           Permease of the major facilitator superfamily -
           Lactobacillus casei (strain ATCC 334)
          Length = 482

 Score = 38.3 bits (85), Expect = 0.25
 Identities = 29/97 (29%), Positives = 47/97 (48%), Gaps = 1/97 (1%)
 Frame = +3

Query: 348 SPIYGAHLNRIGPKLLFNTGILTTGTCAILFGLLDRVXGHVPFITLSFVIRIVEAMGNAA 527
           +PIYG   + IG + +F  G+       +LF L   + G  P I L  + R ++ +G  A
Sbjct: 63  TPIYGKLADTIGRRGIFQWGV-------VLFTLGTLLSGLAPHIFLLILARALQGIGAGA 115

Query: 528 FLTASFAIIAKEFP-NNVATMFASIETFFGLGLIVGP 635
            +  +F IIA  +   + A + A   T + L  +VGP
Sbjct: 116 VMPLTFTIIADYYDFAHRANVLALNNTAWRLSALVGP 152


>UniRef50_Q74D39 Cluster: Drug resistance transporter, EmrB/QacA
           family; n=6; Desulfuromonadales|Rep: Drug resistance
           transporter, EmrB/QacA family - Geobacter sulfurreducens
          Length = 517

 Score = 37.5 bits (83), Expect = 0.44
 Identities = 22/71 (30%), Positives = 34/71 (47%)
 Frame = +3

Query: 423 TCAILFGLLDRVXGHVPFITLSFVIRIVEAMGNAAFLTASFAIIAKEFPNNVATMFASIE 602
           +C  LF +   + G  P +T     RIV+     A + +S AI+ + FP     M  +I 
Sbjct: 82  SCITLFTIASFLCGAAPNLTSLIFFRIVQGAAGGALIPSSQAILMETFPPRERGMANAI- 140

Query: 603 TFFGLGLIVGP 635
             FG+G + GP
Sbjct: 141 --FGIGAMFGP 149


>UniRef50_Q6L134 Cluster: Resistance protein; n=1; Picrophilus
           torridus|Rep: Resistance protein - Picrophilus torridus
          Length = 440

 Score = 37.5 bits (83), Expect = 0.44
 Identities = 19/68 (27%), Positives = 30/68 (44%)
 Frame = +3

Query: 432 ILFGLLDRVXGHVPFITLSFVIRIVEAMGNAAFLTASFAIIAKEFPNNVATMFASIETFF 611
           +LF L        P+I LS ++R +E +G          +I   F +N +T        +
Sbjct: 79  LLFSLSSLGITVSPYIILSIILRFIEGLGAGILSITDIPVILDAFDDNKSTAIGINSISW 138

Query: 612 GLGLIVGP 635
           G+G I GP
Sbjct: 139 GIGTIAGP 146


>UniRef50_Q4DHV4 Cluster: Putative uncharacterized protein; n=2;
           Trypanosoma cruzi|Rep: Putative uncharacterized protein
           - Trypanosoma cruzi
          Length = 539

 Score = 36.7 bits (81), Expect = 0.76
 Identities = 26/94 (27%), Positives = 39/94 (41%)
 Frame = +3

Query: 357 YGAHLNRIGPKLLFNTGILTTGTCAILFGLLDRVXGHVPFITLSFVIRIVEAMGNAAFLT 536
           +G   +R G K +   G+      AI FG+        P I    ++R +    N   L 
Sbjct: 71  WGRMSDRFGRKPMIQLGLFFNAVIAIFFGVS-------PSIEFCILMRFLHGCANGNVLV 123

Query: 537 ASFAIIAKEFPNNVATMFASIETFFGLGLIVGPT 638
           A   I         +  F++I  F+G+G IVGPT
Sbjct: 124 AKTVIADITDRTTESLGFSAITLFWGVGSIVGPT 157


>UniRef50_Q8NRB5 Cluster: Permeases of the major facilitator
           superfamily; n=3; Corynebacterium|Rep: Permeases of the
           major facilitator superfamily - Corynebacterium
           glutamicum (Brevibacterium flavum)
          Length = 405

 Score = 35.9 bits (79), Expect = 1.3
 Identities = 37/170 (21%), Positives = 72/170 (42%), Gaps = 1/170 (0%)
 Frame = +3

Query: 198 IVVIGIADFCNAICVALQAPFYPKEAEKKGCTATEYXXXXXXXXXXXXXXSPIYGAHLNR 377
           I V+ +A F  A+   L AP  P+       +                  +P+ G+ +++
Sbjct: 18  IWVLVVAAFIIALGYGLIAPILPQFVVGFDVSFAAASAVVSIFAGARLLFAPMSGSLIDK 77

Query: 378 IGPKLLFNTGILTTGTCAILFGLLDRVXGHVPFITLSFVIRIVEAMGNAAFLTASFAIIA 557
           IG + ++ TG+LT    AI  GL+     +   +    ++R +  +G+  F  ++  +I 
Sbjct: 78  IGSRRVYLTGLLTV---AITTGLVALAQEYWQIL----LLRGIAGIGSTMFTVSAMGLIV 130

Query: 558 KEFPNNVATMFASI-ETFFGLGLIVGPTXXXXXXXXXXXSLPFAVLGSAL 704
           K  P  +    +S+  + F  G I+GP              PFA+ G+++
Sbjct: 131 KMAPVEIRGRCSSVYASSFLFGNIIGPV-VGAAMSGLGMRWPFAIYGASV 179


>UniRef50_Q18V64 Cluster: Major facilitator superfamily MFS_1; n=2;
           Desulfitobacterium hafniense|Rep: Major facilitator
           superfamily MFS_1 - Desulfitobacterium hafniense (strain
           DCB-2)
          Length = 462

 Score = 35.9 bits (79), Expect = 1.3
 Identities = 23/85 (27%), Positives = 45/85 (52%)
 Frame = +3

Query: 360 GAHLNRIGPKLLFNTGILTTGTCAILFGLLDRVXGHVPFITLSFVIRIVEAMGNAAFLTA 539
           G  ++RIG + +   G+L T   +ILFGL      H   +  +++ R +  +G++  + +
Sbjct: 92  GILVDRIGVRKINFCGLLVTAAGSILFGL-----AHT--LEAAYLSRFLVGIGSSVIIVS 144

Query: 540 SFAIIAKEFPNNVATMFASIETFFG 614
            F I A  FP +  ++ + + +FFG
Sbjct: 145 IFKIQATWFPLSRFSVLSGLTSFFG 169


>UniRef50_A5FA66 Cluster: Drug resistance transporter, EmrB/QacA
           subfamily; n=2; Flavobacterium|Rep: Drug resistance
           transporter, EmrB/QacA subfamily - Flavobacterium
           johnsoniae UW101
          Length = 529

 Score = 35.9 bits (79), Expect = 1.3
 Identities = 22/69 (31%), Positives = 34/69 (49%)
 Frame = +3

Query: 432 ILFGLLDRVXGHVPFITLSFVIRIVEAMGNAAFLTASFAIIAKEFPNNVATMFASIETFF 611
           I+F +   + G+   I      R V+ MG  A L  +  II + +P     M  +I   +
Sbjct: 93  IIFTVCSFLCGNATNIWELVAFRFVQGMGGGALLVTAQTIITESYPVAKRGMAQAI---Y 149

Query: 612 GLGLIVGPT 638
           G+G+IVGPT
Sbjct: 150 GMGVIVGPT 158


>UniRef50_A4L2N9 Cluster: Permease; n=10; Lactobacillus|Rep:
           Permease - Lactobacillus reuteri
          Length = 407

 Score = 35.9 bits (79), Expect = 1.3
 Identities = 30/124 (24%), Positives = 57/124 (45%), Gaps = 3/124 (2%)
 Frame = +3

Query: 348 SPIYGAHLNRIGPKLLFN--TGILTTGTCAILFGLLDRVXGHVPFITLSFVIRIVEAMGN 521
           SP +G+  +R G KL+    +G++    CAI         G    + +   +R ++ + +
Sbjct: 73  SPFWGSLADRKGRKLMCMRASGVMACTICAI---------GFAQSVWMIIGMRFLQGVFS 123

Query: 522 AAFLTASFAIIAKEFPNNVATMFASIETFFGL-GLIVGPTXXXXXXXXXXXSLPFAVLGS 698
             ++  + A++A E P+N +    S  T  G+ G +VGP             +PF + G+
Sbjct: 124 G-YINNATALMAGETPHNKSGWVMSAMTTAGVAGNLVGPLLGGFLSELFGYRIPFFITGA 182

Query: 699 ALFC 710
            +FC
Sbjct: 183 LMFC 186


>UniRef50_Q6MQ30 Cluster: Tetracycline-efflux transporter; n=1;
           Bdellovibrio bacteriovorus|Rep: Tetracycline-efflux
           transporter - Bdellovibrio bacteriovorus
          Length = 367

 Score = 35.5 bits (78), Expect = 1.8
 Identities = 26/96 (27%), Positives = 39/96 (40%)
 Frame = +3

Query: 348 SPIYGAHLNRIGPKLLFNTGILTTGTCAILFGLLDRVXGHVPFITLSFVIRIVEAMGNAA 527
           SP+ GA  +R G + +    +L  G   IL         + P + + F  RI+  +  A 
Sbjct: 30  SPLLGALSDRFGRRSVLLISLLVAGFDYILMA-------YAPTLEILFAGRIIAGLTGAN 82

Query: 528 FLTASFAIIAKEFPNNVATMFASIETFFGLGLIVGP 635
              A   I       N +  F  +   FGLG I+GP
Sbjct: 83  ITVAMAYIADVSNDENRSANFGMVGAAFGLGFIIGP 118


>UniRef50_A4VC93 Cluster: Permease of the major facilitator
           superfamily; n=3; Lactobacillales|Rep: Permease of the
           major facilitator superfamily - Lactococcus lactis
          Length = 457

 Score = 35.5 bits (78), Expect = 1.8
 Identities = 28/87 (32%), Positives = 40/87 (45%), Gaps = 1/87 (1%)
 Frame = +3

Query: 348 SPIYGAHLNRIGPKLLFNTG-ILTTGTCAILFGLLDRVXGHVPFITLSFVIRIVEAMGNA 524
           +PI G  L+R GP+++   G +L TG     FGLL     H+P I    +    EA GNA
Sbjct: 314 NPISGRLLDRFGPRVVAMIGMLLITGG----FGLLAVFTHHLPLIGAIMLAMATEA-GNA 368

Query: 525 AFLTASFAIIAKEFPNNVATMFASIET 605
             +  S    A   PN +     ++ T
Sbjct: 369 FVMMPSVTAGANALPNELVADGTAVTT 395


>UniRef50_Q4Q5T8 Cluster: Putative uncharacterized protein; n=3;
           Leishmania|Rep: Putative uncharacterized protein -
           Leishmania major
          Length = 635

 Score = 35.5 bits (78), Expect = 1.8
 Identities = 28/92 (30%), Positives = 42/92 (45%), Gaps = 2/92 (2%)
 Frame = +3

Query: 351 PIYGAHLNRIGPKLLFNTGILTTGTCAILFGL--LDRVXGHVPFITLSFVIRIVEAMGNA 524
           P+ G + +  GP+ LF  G++       LFGL   D V G V   T   +      +G +
Sbjct: 93  PLAGLY-DYYGPRPLFLIGMIILPLGEALFGLSFADAVDGSVVRFT---IFSAFLGVGTS 148

Query: 525 AFLTASFAIIAKEFPNNVATMFASIETFFGLG 620
            F  A    I   FP++   + A ++TF GLG
Sbjct: 149 MFDIAGLMTILSVFPSSRGAVIAVMKTFIGLG 180


>UniRef50_Q5TBJ2 Cluster: OTTHUMP00000017233; n=1; Homo sapiens|Rep:
           OTTHUMP00000017233 - Homo sapiens (Human)
          Length = 107

 Score = 35.5 bits (78), Expect = 1.8
 Identities = 14/41 (34%), Positives = 24/41 (58%)
 Frame = +3

Query: 177 SKRQWLTIVVIGIADFCNAICVALQAPFYPKEAEKKGCTAT 299
           S+ Q   ++     +  + +C ++  PF+PKEAEKKG + T
Sbjct: 30  SREQVFVLISAASVNLGSMMCYSILGPFFPKEAEKKGASNT 70


>UniRef50_Q39KV2 Cluster: Major facilitator superfamily (MFS_1)
           transporter; n=23; Proteobacteria|Rep: Major facilitator
           superfamily (MFS_1) transporter - Burkholderia sp.
           (strain 383) (Burkholderia cepacia (strain ATCC 17760/
           NCIB 9086 / R18194))
          Length = 537

 Score = 35.1 bits (77), Expect = 2.3
 Identities = 28/93 (30%), Positives = 42/93 (45%), Gaps = 1/93 (1%)
 Frame = +3

Query: 360 GAHLNRIGPKLLFNTGILTTGTCAILFGLLDRVXGHVPFITLSFVIRIVEAMGNAAFLTA 539
           GA  ++ G K LF  G+   G     F L+       P +    ++R  + +  AA L  
Sbjct: 74  GALADQFGRKRLFAIGV---GG----FTLMSVALAFAPSMLAVDLLRAAQGLAAAAALAG 126

Query: 540 SFAIIAKEFPNNVATM-FASIETFFGLGLIVGP 635
             A +A+EF     T  F+ + T FG+GL  GP
Sbjct: 127 GTAALAQEFDGAARTRAFSLLGTTFGIGLAFGP 159


>UniRef50_O31131 Cluster: Putative efflux protein; n=1;
           Brevibacterium linens|Rep: Putative efflux protein -
           Brevibacterium linens
          Length = 489

 Score = 35.1 bits (77), Expect = 2.3
 Identities = 21/69 (30%), Positives = 33/69 (47%), Gaps = 1/69 (1%)
 Frame = +3

Query: 432 ILFGLLDRVXGHVPFITLSFVIRIVEAMGNAAFLTASFAIIAKEFPNNVAT-MFASIETF 608
           +++ L   +    P I++  V R++  MG AA +    A  A  F     + MFA+I T 
Sbjct: 81  VIYVLGGAIAAFAPTISILLVGRVLSGMGAAAVMAGGAATAAAAFNGPARSRMFAAIGTA 140

Query: 609 FGLGLIVGP 635
             +GL  GP
Sbjct: 141 AAIGLAAGP 149


>UniRef50_A7I9X1 Cluster: Major facilitator superfamily MFS_1; n=1;
           Candidatus Methanoregula boonei 6A8|Rep: Major
           facilitator superfamily MFS_1 - Methanoregula boonei
           (strain 6A8)
          Length = 470

 Score = 35.1 bits (77), Expect = 2.3
 Identities = 21/57 (36%), Positives = 31/57 (54%), Gaps = 1/57 (1%)
 Frame = +3

Query: 468 VPFITLSFVIRIVEAMGNAAFLTASFAIIAKEFP-NNVATMFASIETFFGLGLIVGP 635
           +P + LS   RIV+ +G A  ++ S AII + FP +        +    GLGLI+GP
Sbjct: 107 LPLLVLS---RIVQGIGAAMLMSISMAIIMQVFPLHERGKALGYVTATVGLGLIIGP 160


>UniRef50_A2SRS3 Cluster: Drug resistance transporter, EmrB/QacA
           subfamily; n=1; Methanocorpusculum labreanum Z|Rep: Drug
           resistance transporter, EmrB/QacA subfamily -
           Methanocorpusculum labreanum (strain ATCC 43576 / DSM
           4855 / Z)
          Length = 470

 Score = 35.1 bits (77), Expect = 2.3
 Identities = 37/152 (24%), Positives = 61/152 (40%), Gaps = 1/152 (0%)
 Frame = +3

Query: 183 RQWLTIVVIGIADFCNAICVALQAPFYPKEAEKKGCTATEYXXXXXXXXXXXXXXSPIYG 362
           RQ L ++ +GIA F +A+  ++     P  A + G                      I+G
Sbjct: 10  RQKLLLLAVGIAVFVDALDGSVVNIALPVIAAEFGADTGTISWVSLAYLLTLAGLILIFG 69

Query: 363 AHLNRIGPKLLFNTGILTTGTCAILFGLLDRVXGHVPFITLSFVIRIVEAMGNAAFLTAS 542
              +R   K+LF  G +    C+I+ GL        P ++   V RI + +G A    ++
Sbjct: 70  KLADRGYVKILFIAGFVLFTLCSIVCGL-------SPDLSFLIVARIFQGVGAAMIAAST 122

Query: 543 FAIIAKEFPNNVATMFASIET-FFGLGLIVGP 635
             I  K  P N+  +   + T    +G  VGP
Sbjct: 123 PMICVKYLPANMLGVSMGVLTAASSIGFAVGP 154


>UniRef50_Q9RYR1 Cluster: Drug transport protein, putative; n=2;
           Deinococcus|Rep: Drug transport protein, putative -
           Deinococcus radiodurans
          Length = 698

 Score = 34.7 bits (76), Expect = 3.1
 Identities = 31/99 (31%), Positives = 44/99 (44%), Gaps = 4/99 (4%)
 Frame = +3

Query: 351 PIYGAHLNRIGPKLLFNTGILTTGTCAILFGLL-DRVXGHVPFITLSFVI--RIVEAMGN 521
           PIYG   +  G K +   GIL     + L GL  +   G+     ++ +I  R V   G 
Sbjct: 86  PIYGKLSDLYGRKPILIFGILVFLFGSALCGLAGEPFLGNFLGGGMNQLIAFRAVAGFGG 145

Query: 522 AAFLTASFAIIAKEF-PNNVATMFASIETFFGLGLIVGP 635
           AA  T +F I+A  F P   A         FGL +++GP
Sbjct: 146 AALFTTAFTILADMFDPTERAKFGGLFGAIFGLSMVLGP 184


>UniRef50_Q3BM88 Cluster: Drug:H+ antiporter-1 family protein; n=5;
           Xanthomonas|Rep: Drug:H+ antiporter-1 family protein -
           Xanthomonas campestris pv. vesicatoria (strain 85-10)
          Length = 449

 Score = 34.7 bits (76), Expect = 3.1
 Identities = 26/96 (27%), Positives = 44/96 (45%)
 Frame = +3

Query: 348 SPIYGAHLNRIGPKLLFNTGILTTGTCAILFGLLDRVXGHVPFITLSFVIRIVEAMGNAA 527
           SP+ GA  +R G + +     L  G   IL  +   +    P + L+   R++  + +A+
Sbjct: 101 SPLQGALSDRFGRRPVILLSCLGLGLDFILMAIAHSL----PMLLLA---RVISGVCSAS 153

Query: 528 FLTASFAIIAKEFPNNVATMFASIETFFGLGLIVGP 635
           F TA+  I     P+  A  F  +   FG+G + GP
Sbjct: 154 FSTANAYIADVTPPDKRAGAFGMLGAAFGIGFVAGP 189


>UniRef50_A5FEH6 Cluster: Drug resistance transporter, EmrB/QacA
           subfamily; n=1; Flavobacterium johnsoniae UW101|Rep:
           Drug resistance transporter, EmrB/QacA subfamily -
           Flavobacterium johnsoniae UW101
          Length = 516

 Score = 34.7 bits (76), Expect = 3.1
 Identities = 18/69 (26%), Positives = 33/69 (47%)
 Frame = +3

Query: 432 ILFGLLDRVXGHVPFITLSFVIRIVEAMGNAAFLTASFAIIAKEFPNNVATMFASIETFF 611
           +LF     + GH   I +    R  + +G  A L+ S  ++ + FP +  +   ++   F
Sbjct: 81  VLFTFCSFMCGHSSNIWMLVFFRFFQGIGGGALLSISQVVVFELFPKDKQSTAGAL---F 137

Query: 612 GLGLIVGPT 638
           G G+ +GPT
Sbjct: 138 GAGIFIGPT 146


>UniRef50_Q4CUF8 Cluster: Putative uncharacterized protein; n=2;
           Trypanosoma cruzi|Rep: Putative uncharacterized protein
           - Trypanosoma cruzi
          Length = 617

 Score = 34.7 bits (76), Expect = 3.1
 Identities = 24/89 (26%), Positives = 40/89 (44%), Gaps = 1/89 (1%)
 Frame = +3

Query: 357 YGAHLNRIGPKLLFNTGILTTGTCAILFGLLDRVXGHVPFITLSF-VIRIVEAMGNAAFL 533
           YG   +  GP+ ++    +   T A+LFGL      H+   T+ F V   + ++G+    
Sbjct: 87  YGVIYDHFGPRPIYVLACVLLATGALLFGL--SFGDHIEGSTVRFCVYNAMLSLGSELLD 144

Query: 534 TASFAIIAKEFPNNVATMFASIETFFGLG 620
            A    +   FP N   + A ++T  GLG
Sbjct: 145 MACGLTLLSIFPTNRGGVVAFLKTLLGLG 173


>UniRef50_A0E3U2 Cluster: Chromosome undetermined scaffold_77, whole
           genome shotgun sequence; n=2; Paramecium
           tetraurelia|Rep: Chromosome undetermined scaffold_77,
           whole genome shotgun sequence - Paramecium tetraurelia
          Length = 569

 Score = 34.7 bits (76), Expect = 3.1
 Identities = 21/83 (25%), Positives = 38/83 (45%)
 Frame = +3

Query: 387 KLLFNTGILTTGTCAILFGLLDRVXGHVPFITLSFVIRIVEAMGNAAFLTASFAIIAKEF 566
           K +   G++     +I+ G+   + G + FI LS  +R ++ + N      S++I    F
Sbjct: 222 KKMILQGLIGQLVISIILGISYFLNGALFFI-LSSFLRFIQGISNTMIQVPSYSITGHLF 280

Query: 567 PNNVATMFASIETFFGLGLIVGP 635
              V+   A +E     GL+ GP
Sbjct: 281 SEQVSEKIAKLEMACNFGLVCGP 303


>UniRef50_Q8U4E5 Cluster: Quinolone resistance protein norA homolog;
           n=4; Thermococcaceae|Rep: Quinolone resistance protein
           norA homolog - Pyrococcus furiosus
          Length = 387

 Score = 34.7 bits (76), Expect = 3.1
 Identities = 27/95 (28%), Positives = 44/95 (46%), Gaps = 2/95 (2%)
 Frame = +3

Query: 354 IYGAHLNRI-GPKLLFNTGILTTGTCAILFGLLDRVXGHVPFITLSFVIRIVEAMGNAAF 530
           ++G  +  I GP  +   GIL  G+  +          + PF   SF++ +V  +G    
Sbjct: 257 VFGGKIADIKGPIPVARVGILILGSSYLALAFNQ----YPPF---SFIVGVVSGLGFGLL 309

Query: 531 LTASFAIIAKEFPNNVATMFASIET-FFGLGLIVG 632
           + A   +     P N+ TM +SI T FF LG++ G
Sbjct: 310 IPALQYMALANLPGNIRTMGSSIYTMFFDLGMLSG 344


>UniRef50_Q5V1E4 Cluster: Transporter possibly hexose; n=5;
           Halobacteriaceae|Rep: Transporter possibly hexose -
           Haloarcula marismortui (Halobacterium marismortui)
          Length = 449

 Score = 34.7 bits (76), Expect = 3.1
 Identities = 33/100 (33%), Positives = 44/100 (44%), Gaps = 8/100 (8%)
 Frame = +3

Query: 360 GAHLNRIGPKLLFNTGILTTGTCAILFGLLDRVXGHV-------PFITLSFVIRIVEAMG 518
           GA  +RIG +L   T   T  T       L  V G V       P  TL FV   +    
Sbjct: 81  GAVSDRIGSRLAL-TAFATLATVGFGIWYLASVIGDVTLGATTLPAWTLVFVGLFLAQAW 139

Query: 519 NAAFLTASFAIIAKEFP-NNVATMFASIETFFGLGLIVGP 635
            +  L A+FAI+ +  P   +A  FAS E F  +G ++GP
Sbjct: 140 KSFGLGATFAIVKQSVPPQRLAMGFASTEMFRRIGFLLGP 179


>UniRef50_Q9A8S0 Cluster: Tetracycline resistance protein; n=3;
           Alphaproteobacteria|Rep: Tetracycline resistance protein
           - Caulobacter crescentus (Caulobacter vibrioides)
          Length = 586

 Score = 34.3 bits (75), Expect = 4.1
 Identities = 28/96 (29%), Positives = 38/96 (39%)
 Frame = +3

Query: 348 SPIYGAHLNRIGPKLLFNTGILTTGTCAILFGLLDRVXGHVPFITLSFVIRIVEAMGNAA 527
           SPI G   +R G + +  T I   G   +            P +   F+ RI   M  A+
Sbjct: 239 SPILGLLSDRFGRRPVILTSIFGLGIDFLFMAF-------APNLWWLFIGRIFNGMTAAS 291

Query: 528 FLTASFAIIAKEFPNNVATMFASIETFFGLGLIVGP 635
           F TAS  +     P N A  F  +   FG+G   GP
Sbjct: 292 FSTASAYVADVTTPENRAKGFGLMGAAFGIGFTFGP 327


>UniRef50_Q1GPE1 Cluster: Major facilitator superfamily MFS_1; n=2;
           Sphingomonadaceae|Rep: Major facilitator superfamily
           MFS_1 - Sphingopyxis alaskensis (Sphingomonas
           alaskensis)
          Length = 412

 Score = 34.3 bits (75), Expect = 4.1
 Identities = 36/134 (26%), Positives = 57/134 (42%), Gaps = 3/134 (2%)
 Frame = +3

Query: 348 SPIYGAHLNRIGPKLLFNTGILTTGTCAILFGLLDRVXGHVPFITLSFVIRIVEAMGNAA 527
           SP+ G   +R G + +    +L  G  A+ + LL  V   +P++   FV R +  +   +
Sbjct: 62  SPVLGNLSDRFGRRRIL---LLALGGLAVDYALLT-VVETLPWL---FVARALSGIFGGS 114

Query: 528 FLTASFAIIAKEFPNNVATMFASIETFFGLGLIVGPTXXXXXXXXXXXSLPF---AVLGS 698
           +  A  AI     P   A  F  +   FG+G + GP            + PF   A+L +
Sbjct: 115 YAAAQAAIADITPPEERARNFGFVGAAFGVGFVAGPAIGGFLGEMSPRA-PFVAAAILAT 173

Query: 699 ALFCXAGYELFPLT 740
           A     GY +FP T
Sbjct: 174 ANMLY-GYFIFPET 186


>UniRef50_A6TX73 Cluster: Major facilitator superfamily MFS_1; n=1;
           Alkaliphilus metalliredigens QYMF|Rep: Major facilitator
           superfamily MFS_1 - Alkaliphilus metalliredigens QYMF
          Length = 391

 Score = 34.3 bits (75), Expect = 4.1
 Identities = 27/94 (28%), Positives = 45/94 (47%), Gaps = 1/94 (1%)
 Frame = +3

Query: 357 YGAHLNRIGPKLLFNTGILTTGTCAILFGLLDRVXGHVPFITLSFVIRIVEAMGNAAFLT 536
           +G   +R+G K+     +L    C  L  LL      +  +TL+   R+++A+G +AFL+
Sbjct: 62  FGPLADRVGRKI----PLLIGTACFALTSLLFYYSNSLWLLTLA---RMLQALGLSAFLS 114

Query: 537 ASFAIIAKEFP-NNVATMFASIETFFGLGLIVGP 635
           +S + +A   P N V T            L+VGP
Sbjct: 115 SSISAVADMAPVNKVGTYMGVYRLIGAFALLVGP 148


>UniRef50_A3UH39 Cluster: Multidrug resistance protein, putative;
           n=2; Hyphomonadaceae|Rep: Multidrug resistance protein,
           putative - Oceanicaulis alexandrii HTCC2633
          Length = 428

 Score = 34.3 bits (75), Expect = 4.1
 Identities = 26/102 (25%), Positives = 46/102 (45%), Gaps = 6/102 (5%)
 Frame = +3

Query: 348 SPIYGAHLNRIGPKLLFNTGILT-TGTCAILF-GLLDRVXGHVP----FITLSFVIRIVE 509
           SP++GA  +R G + L   G+    G+C +   G      G +P     I ++    I  
Sbjct: 70  SPVWGALSDRYGRRPLIVFGLSAFAGSCLVFAAGAWAGQVGLLPPMAAIIAMALARSIFG 129

Query: 510 AMGNAAFLTASFAIIAKEFPNNVATMFASIETFFGLGLIVGP 635
            +G+A   +A   +  +  P+      +S+   FGLG ++GP
Sbjct: 130 GLGSATNPSAQAYVADRTEPSQRTRALSSLTAAFGLGTVIGP 171


>UniRef50_UPI000051033C Cluster: COG0477: Permeases of the major
           facilitator superfamily; n=1; Brevibacterium linens
           BL2|Rep: COG0477: Permeases of the major facilitator
           superfamily - Brevibacterium linens BL2
          Length = 444

 Score = 33.9 bits (74), Expect = 5.4
 Identities = 24/92 (26%), Positives = 42/92 (45%), Gaps = 1/92 (1%)
 Frame = +3

Query: 348 SPIYGAHLNRIGPKLLFNTGILTTGTCAILFGLLDRVXGHVPFITLSFVIRIVEAMGNAA 527
           SP++G   +R GP  +   G+L   T AI+ G++D        + LS  + I   +G + 
Sbjct: 290 SPVFGWMADRWGPGTVIAGGVLVFAT-AIILGVIDATAEVSSMVLLSIAL-IFLGIGWSM 347

Query: 528 FLTASFAIIAKEFPNNV-ATMFASIETFFGLG 620
           FL    A++    P +   T+  + +    LG
Sbjct: 348 FLIGGSALLTASVPQHAKVTLQGASDAAMNLG 379


>UniRef50_Q7U3D8 Cluster: Multidrug efflux transporter, MFS family;
           n=17; Cyanobacteria|Rep: Multidrug efflux transporter,
           MFS family - Synechococcus sp. (strain WH8102)
          Length = 432

 Score = 33.9 bits (74), Expect = 5.4
 Identities = 17/53 (32%), Positives = 24/53 (45%)
 Frame = +3

Query: 477 ITLSFVIRIVEAMGNAAFLTASFAIIAKEFPNNVATMFASIETFFGLGLIVGP 635
           + L F  RI++ +      TA+  +     P N A  F  I   FGLG  +GP
Sbjct: 127 LALLFTARIIDGISGGTAATATAVLADVTTPENRAKAFGLIGVAFGLGFALGP 179


>UniRef50_Q04U94 Cluster: Permease; n=5; Bacteria|Rep: Permease -
           Leptospira borgpetersenii serovar Hardjo-bovis (strain
           JB197)
          Length = 408

 Score = 33.9 bits (74), Expect = 5.4
 Identities = 26/71 (36%), Positives = 32/71 (45%), Gaps = 2/71 (2%)
 Frame = +3

Query: 429 AILFGL-LDRVX-GHVPFITLSFVIRIVEAMGNAAFLTASFAIIAKEFPNNVATMFASIE 602
           A LFG  LD +     P I   FV R+V  +  A+F T    I     P   A  F  + 
Sbjct: 86  ASLFGFTLDYLFLAFAPSIFWLFVGRVVSGIMGASFTTGYAYIADISPPEKRAQNFGILG 145

Query: 603 TFFGLGLIVGP 635
             FGLG I+GP
Sbjct: 146 AAFGLGFIIGP 156


>UniRef50_A7H904 Cluster: Major facilitator superfamily MFS_1; n=1;
           Anaeromyxobacter sp. Fw109-5|Rep: Major facilitator
           superfamily MFS_1 - Anaeromyxobacter sp. Fw109-5
          Length = 416

 Score = 33.9 bits (74), Expect = 5.4
 Identities = 25/89 (28%), Positives = 40/89 (44%), Gaps = 1/89 (1%)
 Frame = +3

Query: 372 NRIGPKLLFNTGILTTGTCAILFGLLDRVXGHVPFITLSFVIRIVEAMGNAAFLTASFAI 551
           +R+G + L+  G+L     + L GL   +   V         R+V+A+G +A +    AI
Sbjct: 76  DRLGHRALYAGGLLVFTAGSALCGLAGGLGALV-------AARVVQALGASAMMAIGPAI 128

Query: 552 IAKEFPNNV-ATMFASIETFFGLGLIVGP 635
           +   FP  V      ++ T   LGL  GP
Sbjct: 129 VTAAFPPTVRGRALGAVGTVVALGLTAGP 157


>UniRef50_A5D3X1 Cluster: Xanthine/uracil permeases; n=1;
           Pelotomaculum thermopropionicum SI|Rep: Xanthine/uracil
           permeases - Pelotomaculum thermopropionicum SI
          Length = 448

 Score = 33.9 bits (74), Expect = 5.4
 Identities = 23/82 (28%), Positives = 39/82 (47%)
 Frame = +3

Query: 384 PKLLFNTGILTTGTCAILFGLLDRVXGHVPFITLSFVIRIVEAMGNAAFLTASFAIIAKE 563
           P+  ++ G+  TG   IL GL   V G VP+   + ++ +        F+  SFA++A  
Sbjct: 286 PQRTYDRGVALTGFSDILAGLGATV-GFVPYSAGAGMVSMTRVAARLPFIVFSFALMALG 344

Query: 564 FPNNVATMFASIETFFGLGLIV 629
               VA+  ASI    G  +++
Sbjct: 345 LLPPVASFLASIPEPVGYSVLL 366


>UniRef50_Q9V3J5 Cluster: EG:BACR7A4.13 protein; n=1; Drosophila
           melanogaster|Rep: EG:BACR7A4.13 protein - Drosophila
           melanogaster (Fruit fly)
          Length = 558

 Score = 33.9 bits (74), Expect = 5.4
 Identities = 25/92 (27%), Positives = 44/92 (47%), Gaps = 1/92 (1%)
 Frame = +3

Query: 360 GAHLNRIGPKLLFNTGILTTGTCAILFGLLDRVXGHVPFITLSFVIRIVEAMGNAAFLTA 539
           G  +N +G KL+  +G+L    C+I           V   +L   +  + A    + ++A
Sbjct: 432 GFLVNLVGVKLIMTSGLLIAAGCSIGMYWSSSAASTVALASLFVTMGSISA---TSVISA 488

Query: 540 SFAIIAKEFPNNVATMFASIETFFG-LGLIVG 632
           S ++    FP ++ TM  S+E  FG LG ++G
Sbjct: 489 SVSL----FPTSLRTMIVSLEMMFGRLGSLLG 516


>UniRef50_Q4UGZ5 Cluster: Putative uncharacterized protein; n=3;
            Theileria|Rep: Putative uncharacterized protein -
            Theileria annulata
          Length = 1574

 Score = 33.9 bits (74), Expect = 5.4
 Identities = 16/35 (45%), Positives = 21/35 (60%)
 Frame = -2

Query: 691  STANGRL*XXNPYSAPPRVGPTMRPKPKNVSIDAN 587
            +T++G+     PY  PP V PT+ P PKNVS   N
Sbjct: 1493 ATSSGKFALVQPY--PPNVNPTLAPFPKNVSGSGN 1525


>UniRef50_Q6KYT7 Cluster: Tetracycline resistance protein; n=1;
           Picrophilus torridus|Rep: Tetracycline resistance
           protein - Picrophilus torridus
          Length = 384

 Score = 33.9 bits (74), Expect = 5.4
 Identities = 33/148 (22%), Positives = 54/148 (36%)
 Frame = +3

Query: 192 LTIVVIGIADFCNAICVALQAPFYPKEAEKKGCTATEYXXXXXXXXXXXXXXSPIYGAHL 371
           L + V  + DF     +   APFY ++    G T  E+              SP  G   
Sbjct: 6   LPLFVTAMIDFIGFGIIIPIAPFYTRDL---GATPFEFSILLVVYSLAQFIASPYLGRLS 62

Query: 372 NRIGPKLLFNTGILTTGTCAILFGLLDRVXGHVPFITLSFVIRIVEAMGNAAFLTASFAI 551
           +RIG K      +L  G    + G L  + G  P ++L ++ R +    +         +
Sbjct: 63  DRIGRK-----NVLVLGLSGEIAGYL--IFGLSPVLSLLYIGRAITGATSGNLPVIYSFV 115

Query: 552 IAKEFPNNVATMFASIETFFGLGLIVGP 635
             K   +N       I    G+G ++GP
Sbjct: 116 SDKTSSDNRTRAIGMIGAAIGIGFVIGP 143


>UniRef50_UPI000050FAA6 Cluster: COG0477: Permeases of the major
           facilitator superfamily; n=1; Brevibacterium linens
           BL2|Rep: COG0477: Permeases of the major facilitator
           superfamily - Brevibacterium linens BL2
          Length = 423

 Score = 33.5 bits (73), Expect = 7.1
 Identities = 36/149 (24%), Positives = 55/149 (36%), Gaps = 1/149 (0%)
 Frame = +3

Query: 192 LTIVVIGIADFCNAICVALQAPFYPKEAEKKGCTATEYXXXXXXXXXXXXXXSPIYGAHL 371
           + + VI +A F   + ++  A   P  A + G                    +  +G   
Sbjct: 1   MLLAVILLAQFVIPLSISGTAVALPTIAGELGSDPAPLQWVVNGFNVAFAICTIAWGVWS 60

Query: 372 NRIGPKLLFNTGILTTGTCAILFGLLDRVXGHVPFITLSFVIRIVEAMGNAAFLTASFAI 551
           +RIG    F  GI+              +    P I L    R++  +G+AA LT +  I
Sbjct: 61  DRIGYTRSFQIGIIIAAAGGA-------ISAFAPTIGLLDSGRVIAGIGSAAVLTGAAPI 113

Query: 552 IAKEFPNNV-ATMFASIETFFGLGLIVGP 635
           ++  F     A  FA   T  GLGL  GP
Sbjct: 114 LSHLFHGKAKAKAFALFGTINGLGLAAGP 142


>UniRef50_Q4ZRX5 Cluster: Major facilitator superfamily; n=3;
           Pseudomonas syringae group|Rep: Major facilitator
           superfamily - Pseudomonas syringae pv. syringae (strain
           B728a)
          Length = 521

 Score = 33.5 bits (73), Expect = 7.1
 Identities = 16/49 (32%), Positives = 29/49 (59%), Gaps = 1/49 (2%)
 Frame = +3

Query: 492 VIRIVEAMGNAAFLTASFAIIAKEFPNNVAT-MFASIETFFGLGLIVGP 635
           ++R+V+ +G AA    + + +A+ F     T +F+ + T FG+GL  GP
Sbjct: 110 LLRLVQGLGGAAAFAGAMSSLAQTFHGAERTRVFSLLGTTFGIGLAFGP 158


>UniRef50_Q4KGW4 Cluster: Drug transporter, putative; n=1;
           Pseudomonas fluorescens Pf-5|Rep: Drug transporter,
           putative - Pseudomonas fluorescens (strain Pf-5 / ATCC
           BAA-477)
          Length = 508

 Score = 33.5 bits (73), Expect = 7.1
 Identities = 29/96 (30%), Positives = 45/96 (46%), Gaps = 1/96 (1%)
 Frame = +3

Query: 348 SPIYGAHLNRIGPKLLFNTGILTTGTCAILFGLLDRVXGHVPFITLSFVIRIVEAMGNAA 527
           SP+ G  ++R GP LL  TG+L     A+L    D     +P++  +FV   V  +G A+
Sbjct: 318 SPLVGRLVDRKGPALLIKTGLLLFVLSALLQAGFDGQTS-LPYLLGAFV---VMGLGWAS 373

Query: 528 FLTASFAIIAKEFPNNVATM-FASIETFFGLGLIVG 632
            L  S  +     P  V ++   S+ T   +G  VG
Sbjct: 374 ILGPSTVLGISSVPQEVGSVAMGSLMTLHNVGGGVG 409


>UniRef50_Q3IC21 Cluster: Putative lipoprotein component of a efflux
           transporter; n=3; Gammaproteobacteria|Rep: Putative
           lipoprotein component of a efflux transporter -
           Pseudoalteromonas haloplanktis (strain TAC 125)
          Length = 389

 Score = 33.5 bits (73), Expect = 7.1
 Identities = 17/39 (43%), Positives = 24/39 (61%), Gaps = 1/39 (2%)
 Frame = -2

Query: 652 SAPPRVGPTMRPKPKNVSIDANIVATLLGNS-XAIIAKE 539
           + P RVGP M   P  V+ID + +A  LGNS   ++AK+
Sbjct: 351 NGPARVGPGMPISPNTVTIDTSGIAFTLGNSNNQLVAKQ 389


>UniRef50_Q8VKE2 Cluster: Drug transporter; n=18;
           Corynebacterineae|Rep: Drug transporter - Mycobacterium
           tuberculosis
          Length = 545

 Score = 33.5 bits (73), Expect = 7.1
 Identities = 27/96 (28%), Positives = 40/96 (41%), Gaps = 1/96 (1%)
 Frame = +3

Query: 351 PIYGAHLNRIGPKLLFNTGILTTGTCAILFGLLDRVXGHVPFITLSFVIRIVEAMGNAAF 530
           P  G   +R G + LF   +L        F L   +    P I L  + R+V+  G    
Sbjct: 101 PTAGWAADRFGTRRLFMGSVLA-------FTLGSLLCAVAPNILLLIIFRVVQGFGGGML 153

Query: 531 LTASFAIIAKEF-PNNVATMFASIETFFGLGLIVGP 635
              SFAI+A+E  P  +  + A +     LG + GP
Sbjct: 154 TPVSFAILAREAGPKRLGRVMAVVGIPMLLGPVGGP 189


>UniRef50_A6LRB1 Cluster: Major facilitator superfamily MFS_1; n=1;
           Clostridium beijerinckii NCIMB 8052|Rep: Major
           facilitator superfamily MFS_1 - Clostridium beijerinckii
           NCIMB 8052
          Length = 392

 Score = 33.5 bits (73), Expect = 7.1
 Identities = 29/125 (23%), Positives = 48/125 (38%)
 Frame = +3

Query: 201 VVIGIADFCNAICVALQAPFYPKEAEKKGCTATEYXXXXXXXXXXXXXXSPIYGAHLNRI 380
           V+I + +        +  P  P  A+K G T +                 PI G  L+++
Sbjct: 17  VIINVINLLIFFGFQMLLPTLPLYAKKLGGTNSIIGLVTGAFVVSSVIIRPISGLLLDKL 76

Query: 381 GPKLLFNTGILTTGTCAILFGLLDRVXGHVPFITLSFVIRIVEAMGNAAFLTASFAIIAK 560
           G + +F  G+         + +       VPFI+   +IR +   G  A  TAS  I + 
Sbjct: 77  GRQKVFLVGLFIFIISVFSYSI-------VPFISAIIMIRFIHGFGWGAVSTASNTIASD 129

Query: 561 EFPNN 575
             PN+
Sbjct: 130 NIPND 134


>UniRef50_A0NKB5 Cluster: Permease, major facilitator superfamily;
           n=2; Leuconostocaceae|Rep: Permease, major facilitator
           superfamily - Oenococcus oeni ATCC BAA-1163
          Length = 427

 Score = 33.5 bits (73), Expect = 7.1
 Identities = 28/120 (23%), Positives = 53/120 (44%), Gaps = 6/120 (5%)
 Frame = +3

Query: 348 SPIYGAHLNRIGPKLLFNTGILTTGTCAILFGLLDRVX-GHVPFITLSFVIRIVEAMGNA 524
           +P++G   +++G K +   G++  G   IL+  L R+       IT+  ++ +       
Sbjct: 70  APVWGKLSDKLGRKTVIVAGLMGMGVMFILYTALFRLSISQSKTITILVILLMAVRFLLG 129

Query: 525 AFLT----ASFAIIAK-EFPNNVATMFASIETFFGLGLIVGPTXXXXXXXXXXXSLPFAV 689
            F+T    A+ A +A   +P N A   +S+    GL +++GP             LPF +
Sbjct: 130 IFMTTVPTAANAYMADISYPENRAKDMSSLGLATGLAMVLGPIIGGILSSIGTLYLPFYI 189


>UniRef50_A0NID0 Cluster: Transporter protein; n=2;
           Lactobacillales|Rep: Transporter protein - Oenococcus
           oeni ATCC BAA-1163
          Length = 474

 Score = 33.5 bits (73), Expect = 7.1
 Identities = 31/151 (20%), Positives = 59/151 (39%), Gaps = 1/151 (0%)
 Frame = +3

Query: 186 QWLTIVVIGIADFCNAICVALQAPFYPKEAEKKGCTATEYXXXXXXXXXXXXXXSPIYGA 365
           QW+ ++   I  F + +  ++     PK +        +                  +G 
Sbjct: 6   QWILLISTSIVSFMSTLDASIVNIAVPKMSRDLNVPTNQAEWVVSVYLVLICVLLIFFGK 65

Query: 366 HLNRIGPKLLFNTGILTTGTCAILFGLLDRVXGHVPFITLSFVIRIVEAMGNAAFLTASF 545
             ++IG   +F  G     T   + G L    G    + L    RIV+A+G +  ++ +F
Sbjct: 66  LSDQIGRIPIFQVG-----TLIFIIGSL--ACGLSLNLPLLITARIVQALGASMTMSTNF 118

Query: 546 AIIAKEFPNNVATMFASI-ETFFGLGLIVGP 635
            II + FP+N   +   +  +F  +G + GP
Sbjct: 119 GIITQIFPSNKHGLALGVNSSFVQVGNLAGP 149


>UniRef50_Q9HRX5 Cluster: Multidrug resistance protein homolog; n=1;
           Halobacterium salinarum|Rep: Multidrug resistance
           protein homolog - Halobacterium salinarium
           (Halobacterium halobium)
          Length = 412

 Score = 33.5 bits (73), Expect = 7.1
 Identities = 41/183 (22%), Positives = 66/183 (36%)
 Frame = +3

Query: 198 IVVIGIADFCNAICVALQAPFYPKEAEKKGCTATEYXXXXXXXXXXXXXXSPIYGAHLNR 377
           ++   +A F   + + +  P  P  A++ G                    + + G    R
Sbjct: 33  VLATALATFIAFLGIGVVDPILPSIAKELGADHFMVMFLFTSYLLVTGLANLVAGTLATR 92

Query: 378 IGPKLLFNTGILTTGTCAILFGLLDRVXGHVPFITLSFVIRIVEAMGNAAFLTASFAIIA 557
           IG K   NT ++  G  A+  G    V      +    V+R    +GNA F T + AII 
Sbjct: 93  IGSK---NTMLVGIGIVAVFAGGCALVSS----VESMAVLRGFWGLGNALFTTTALAIIV 145

Query: 558 KEFPNNVATMFASIETFFGLGLIVGPTXXXXXXXXXXXSLPFAVLGSALFCXAGYELFPL 737
                N        E   G G+  GP             LPFA  G+++    G+ +F  
Sbjct: 146 GVSAGNSGRAITLYEAALGFGIACGP-LLGGFLGAQSWRLPFA--GTSVLMLLGF-VFVA 201

Query: 738 TSI 746
           T++
Sbjct: 202 TTV 204


>UniRef50_Q8ZT99 Cluster: Antibiotic resistance (Efflux) protein,
           conjectural; n=3; Pyrobaculum|Rep: Antibiotic resistance
           (Efflux) protein, conjectural - Pyrobaculum aerophilum
          Length = 474

 Score = 33.5 bits (73), Expect = 7.1
 Identities = 18/67 (26%), Positives = 35/67 (52%), Gaps = 1/67 (1%)
 Frame = +3

Query: 432 ILFGLLDRVXGHVPFITLSFVIRIVEAMGNAAFLTASFAIIAKEFPNN-VATMFASIETF 608
           + + +   + G+ P      + R ++ +G A F  A F++I +EFP + V T    +   
Sbjct: 84  LAYAIAVTLTGYAPNFETLLLSRAIQGLGMAMFPLA-FSLIREEFPPHMVPTAQGVVSAM 142

Query: 609 FGLGLIV 629
           FG+G+I+
Sbjct: 143 FGVGIII 149


>UniRef50_Q5SJX2 Cluster: Multidrug resistance protein-related
           protein; n=2; Thermus thermophilus|Rep: Multidrug
           resistance protein-related protein - Thermus
           thermophilus (strain HB8 / ATCC 27634 / DSM 579)
          Length = 390

 Score = 33.1 bits (72), Expect = 9.4
 Identities = 21/70 (30%), Positives = 33/70 (47%), Gaps = 1/70 (1%)
 Frame = +3

Query: 501 IVEAMGNAAFLTASFAIIAKEFPN-NVATMFASIETFFGLGLIVGPTXXXXXXXXXXXSL 677
           ++  +G + FL     ++AK  P  N A ++ S+ T  GLGL +GP              
Sbjct: 303 LLGGLGFSLFLPGWNGLLAKNLPQENRAAIWGSLMTVEGLGLALGPVAGGLLWEAFGLRA 362

Query: 678 PFAVLGSALF 707
           PF + GS +F
Sbjct: 363 PF-LAGSGIF 371


>UniRef50_Q1NQW5 Cluster: Major facilitator superfamily MFS_1; n=2;
           delta proteobacterium MLMS-1|Rep: Major facilitator
           superfamily MFS_1 - delta proteobacterium MLMS-1
          Length = 443

 Score = 33.1 bits (72), Expect = 9.4
 Identities = 40/151 (26%), Positives = 52/151 (34%), Gaps = 5/151 (3%)
 Frame = +3

Query: 183 RQWLTIVVIGIADFCNAICVALQA---PFYPKEAE--KKGCTATEYXXXXXXXXXXXXXX 347
           R+WL ++   +  FC     A  A        EAE    G TA +               
Sbjct: 13  RRWLVVIGAIVVQFCLGTIYAWSAFTGQLTLPEAEGGAYGFTAQQTAWIFSVGLAVFAVT 72

Query: 348 SPIYGAHLNRIGPKLLFNTGILTTGTCAILFGLLDRVXGHVPFITLSFVIRIVEAMGNAA 527
             I G    R GP+ L   G +   T  IL GL+        F+T  F I IV  MG   
Sbjct: 73  MVIAGRLQLRFGPRPLAVAGGVVLATGYILAGLMGST-----FLTQLFFIGIVGGMGIGL 127

Query: 528 FLTASFAIIAKEFPNNVATMFASIETFFGLG 620
                 A+  K FP+    +       FG G
Sbjct: 128 TYVVPIAVGVKWFPDKKGLISGLAVAGFGFG 158


>UniRef50_Q0K446 Cluster: Putative MFS transporter; n=1; Ralstonia
           eutropha H16|Rep: Putative MFS transporter - Ralstonia
           eutropha (strain ATCC 17699 / H16 / DSM 428 / Stanier
           337)(Cupriavidus necator (strain ATCC 17699 / H16 / DSM
           428 / Stanier337))
          Length = 416

 Score = 33.1 bits (72), Expect = 9.4
 Identities = 19/46 (41%), Positives = 22/46 (47%)
 Frame = +3

Query: 498 RIVEAMGNAAFLTASFAIIAKEFPNNVATMFASIETFFGLGLIVGP 635
           R    +G A  LT   AI A  F    AT   +I   FG+G IVGP
Sbjct: 121 RAATGIGEAMQLTVVIAIAASYFARFRATAVGAINFSFGVGAIVGP 166


>UniRef50_A7IIB8 Cluster: Major facilitator superfamily MFS_1; n=1;
           Xanthobacter autotrophicus Py2|Rep: Major facilitator
           superfamily MFS_1 - Xanthobacter sp. (strain Py2)
          Length = 414

 Score = 33.1 bits (72), Expect = 9.4
 Identities = 31/148 (20%), Positives = 52/148 (35%), Gaps = 1/148 (0%)
 Frame = +3

Query: 195 TIVVIGIADFCNAICVALQAPFYPKEAEKKGCTATEYXXXXXXXXXXXXXXSPIYGAHLN 374
           TI  +G+A FC+ +     AP +       G +                      G  ++
Sbjct: 26  TIGAVGVAHFCSHLLQLALAPLFLMMRADLGVSFVALGAVLAVFYLFSGVGQVTAGILVD 85

Query: 375 RIGPKLLFNTGILTTGTCAILFGLLDRVXGHVPFITLSFVIRIVEAMGNAAFLTASFAII 554
           R G   L   G+L  GT     GL       +P   L+        +GN+ +  A  +I+
Sbjct: 86  RFGAHRLLLAGVLLQGTATAAMGLAPHYLVLLPLAALA-------GLGNSVYHPADLSIL 138

Query: 555 A-KEFPNNVATMFASIETFFGLGLIVGP 635
           + K  P  +   FA+      +G  + P
Sbjct: 139 SHKVAPARLGRAFAAHVIAGSIGFALSP 166


>UniRef50_A6EDN7 Cluster: Drug resistance transporter EmrB/QacA
           subfamily protein; n=1; Pedobacter sp. BAL39|Rep: Drug
           resistance transporter EmrB/QacA subfamily protein -
           Pedobacter sp. BAL39
          Length = 515

 Score = 33.1 bits (72), Expect = 9.4
 Identities = 18/69 (26%), Positives = 35/69 (50%)
 Frame = +3

Query: 432 ILFGLLDRVXGHVPFITLSFVIRIVEAMGNAAFLTASFAIIAKEFPNNVATMFASIETFF 611
           ILF +   + G+   +    V RI++ +     ++ + AI+ + +P     +  ++   F
Sbjct: 83  ILFTIASFLCGNATNLEELIVFRILQGIAGGGLISTAQAILIETWPREDVGIATAL---F 139

Query: 612 GLGLIVGPT 638
           GLG +VGPT
Sbjct: 140 GLGAVVGPT 148


>UniRef50_A4T5I8 Cluster: Major facilitator superfamily MFS_1
           precursor; n=1; Mycobacterium gilvum PYR-GCK|Rep: Major
           facilitator superfamily MFS_1 precursor - Mycobacterium
           gilvum PYR-GCK
          Length = 389

 Score = 33.1 bits (72), Expect = 9.4
 Identities = 24/117 (20%), Positives = 49/117 (41%), Gaps = 1/117 (0%)
 Frame = +3

Query: 351 PIYGAHLNRIGPKLLFNTGILTTGTCAILFGLLDRVXGHVPFITLSFVIRIVEAMGNAAF 530
           P++G   +RIG + +   G+      ++ F + D            +  R+ + +G AAF
Sbjct: 61  PLFGTLADRIGARTVLIAGLAVFAVASLSFAVADET-------AWLWAARLGQGIGAAAF 113

Query: 531 LTASFAIIAKEFP-NNVATMFASIETFFGLGLIVGPTXXXXXXXXXXXSLPFAVLGS 698
             A+ A++A+  P +     F +  ++  +G  +GP               FAV+ +
Sbjct: 114 SPAASALVARLAPASGQGRAFGTYGSYKSVGYTLGPLIGGAIVTFGGLQALFAVMAA 170


>UniRef50_A3I9H4 Cluster: Probable multidrug efflux transporter;
           n=1; Bacillus sp. B14905|Rep: Probable multidrug efflux
           transporter - Bacillus sp. B14905
          Length = 384

 Score = 33.1 bits (72), Expect = 9.4
 Identities = 25/95 (26%), Positives = 42/95 (44%), Gaps = 1/95 (1%)
 Frame = +3

Query: 354 IYGAHLNRIGPKLLFNTGILTTGTCAILFGLLDRVXGHVPFITLSFVIRIVEAMGNAAFL 533
           I G   +R GP ++   G+LTTG    L+ L++      P   L  V+R +  +     +
Sbjct: 58  ISGFLTDRKGPFIILIVGLLTTGLSLTLYNLVEE-----PIALL--VVRFIHGLVAGFIV 110

Query: 534 TASFAIIAKEFPNNVATMFASIE-TFFGLGLIVGP 635
            A+F  +A           ++I   F G+  I+GP
Sbjct: 111 PAAFTFLANATEQEKRGKGSAISGAFVGIAAIIGP 145


  Database: uniref50
    Posted date:  Oct 5, 2007 11:19 AM
  Number of letters in database: 575,637,011
  Number of sequences in database:  1,657,284
  
Lambda     K      H
   0.318    0.134    0.401 

Gapped
Lambda     K      H
   0.279   0.0580    0.190 


Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 790,056,082
Number of Sequences: 1657284
Number of extensions: 15150060
Number of successful extensions: 35705
Number of sequences better than 10.0: 85
Number of HSP's better than 10.0 without gapping: 34377
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 35678
length of database: 575,637,011
effective HSP length: 100
effective length of database: 409,908,611
effective search space used: 77062818868
frameshift window, decay const: 40,  0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)

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