BLASTX 2.2.12 [Aug-07-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= MFBP02_F_O16 (901 letters) Database: uniref50 1,657,284 sequences; 575,637,011 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value UniRef50_UPI0000D56CE5 Cluster: PREDICTED: similar to CG6084-PA,... 169 6e-41 UniRef50_Q7PCV3 Cluster: ENSANGP00000031808; n=9; Endopterygota|... 168 2e-40 UniRef50_P45376 Cluster: Aldose reductase; n=21; Bilateria|Rep: ... 168 2e-40 UniRef50_P15121 Cluster: Aldose reductase; n=72; Eumetazoa|Rep: ... 163 4e-39 UniRef50_Q8CI22 Cluster: 2310005E10Rik protein; n=30; Tetrapoda|... 155 1e-36 UniRef50_Q2LZ66 Cluster: GA19341-PA; n=2; Endopterygota|Rep: GA1... 153 8e-36 UniRef50_P14550 Cluster: Alcohol dehydrogenase [NADP+]; n=44; Bi... 148 2e-34 UniRef50_UPI00015B56A2 Cluster: PREDICTED: similar to GA10458-PA... 146 9e-34 UniRef50_Q9VTL0 Cluster: CG6083-PA; n=4; Diptera|Rep: CG6083-PA ... 145 1e-33 UniRef50_UPI0000588153 Cluster: PREDICTED: hypothetical protein;... 143 5e-33 UniRef50_Q9NAI5 Cluster: Putative uncharacterized protein; n=3; ... 141 3e-32 UniRef50_UPI00015B56A3 Cluster: PREDICTED: similar to aldo-keto ... 136 5e-31 UniRef50_Q17DN1 Cluster: Aldo-keto reductase; n=1; Aedes aegypti... 136 9e-31 UniRef50_Q7QK25 Cluster: ENSANGP00000019775; n=2; Anopheles gamb... 135 2e-30 UniRef50_A5KSS3 Cluster: Aldehyde reductase; n=1; candidate divi... 133 7e-30 UniRef50_A7SIT3 Cluster: Predicted protein; n=1; Nematostella ve... 132 1e-29 UniRef50_Q0VGY1 Cluster: 3-alpha-hydroxysteroid dehydrogenase; n... 132 2e-29 UniRef50_A2QBD7 Cluster: Catalytic activity: an alcohol + NADP(+... 132 2e-29 UniRef50_Q17DN0 Cluster: Aldo-keto reductase; n=5; Culicidae|Rep... 131 2e-29 UniRef50_Q7ZWA4 Cluster: Zgc:56622; n=6; cellular organisms|Rep:... 131 3e-29 UniRef50_Q96UH3 Cluster: Aldehyde reductase; n=13; Pezizomycotin... 131 3e-29 UniRef50_Q5BKE9 Cluster: LOC594893 protein; n=5; Xenopus tropica... 128 1e-28 UniRef50_UPI0000E4A7CE Cluster: PREDICTED: similar to LOC553452 ... 128 2e-28 UniRef50_Q96JD6 Cluster: Aldo-keto reductase family 1 member C-l... 125 1e-27 UniRef50_Q7QVQ9 Cluster: GLP_302_44328_45269; n=1; Giardia lambl... 124 2e-27 UniRef50_Q22352 Cluster: Putative uncharacterized protein T08H10... 124 2e-27 UniRef50_Q55FL3 Cluster: Aldo-keto reductase; n=2; Dictyostelium... 124 3e-27 UniRef50_Q7JVH6 Cluster: LD24696p; n=2; Sophophora|Rep: LD24696p... 123 7e-27 UniRef50_P51857 Cluster: 3-oxo-5-beta-steroid 4-dehydrogenase (E... 123 7e-27 UniRef50_Q0PGJ6 Cluster: Aldo-keto reductase; n=32; Magnoliophyt... 121 3e-26 UniRef50_Q8K023 Cluster: Aldo-keto reductase family 1 member C18... 120 4e-26 UniRef50_Q8VC28 Cluster: Aldo-keto reductase family 1 member C13... 120 5e-26 UniRef50_Q54B70 Cluster: Aldehyde reductase; n=2; Dictyostelium ... 118 2e-25 UniRef50_A2EYY6 Cluster: Oxidoreductase, aldo/keto reductase fam... 118 2e-25 UniRef50_A2R6Z3 Cluster: Catalytic activity: an alcohol + NADP(+... 118 2e-25 UniRef50_UPI0000D9A956 Cluster: PREDICTED: similar to aldo-keto ... 118 3e-25 UniRef50_UPI000065D0BD Cluster: Homolog of Homo sapiens "AKR1B1 ... 116 6e-25 UniRef50_Q2S340 Cluster: Aldehyde reductase; n=10; Bacteria|Rep:... 116 1e-24 UniRef50_Q01J82 Cluster: OSIGBa0152K17.5 protein; n=28; Magnolio... 115 1e-24 UniRef50_UPI0000499B0E Cluster: oxidoreductase, aldo/keto reduct... 114 3e-24 UniRef50_UPI00015B4B22 Cluster: PREDICTED: similar to GA15457-PA... 114 3e-24 UniRef50_Q7ZA52 Cluster: Aldose reductase; n=6; Pezizomycotina|R... 114 3e-24 UniRef50_Q10494 Cluster: Probable oxidoreductase C26F1.07; n=2; ... 114 3e-24 UniRef50_UPI00015B4912 Cluster: PREDICTED: similar to aldo-keto ... 113 6e-24 UniRef50_A3C1Z7 Cluster: Putative uncharacterized protein; n=2; ... 113 8e-24 UniRef50_Q16K66 Cluster: Aldo-keto reductase; n=2; Aedes aegypti... 113 8e-24 UniRef50_Q0IBY6 Cluster: Alcohol dehydrogenase; n=2; Chroococcal... 112 1e-23 UniRef50_A2QL02 Cluster: Putative frameshift; n=1; Aspergillus n... 112 1e-23 UniRef50_A3U9Y0 Cluster: Aldehyde reductase; n=5; Bacteroidetes|... 111 2e-23 UniRef50_Q9U2J5 Cluster: Putative uncharacterized protein; n=2; ... 111 3e-23 UniRef50_Q7G764 Cluster: Probable NAD(P)H-dependent oxidoreducta... 111 3e-23 UniRef50_Q6TY50 Cluster: Reductase 2; n=10; Magnoliophyta|Rep: R... 110 4e-23 UniRef50_A2EHN6 Cluster: Oxidoreductase, aldo/keto reductase fam... 110 4e-23 UniRef50_Q7G765 Cluster: Probable NAD(P)H-dependent oxidoreducta... 110 5e-23 UniRef50_Q9FJK0 Cluster: Aldose reductase-like protein; n=3; cor... 108 2e-22 UniRef50_A7PNI3 Cluster: Chromosome chr1 scaffold_22, whole geno... 108 2e-22 UniRef50_P27800 Cluster: Aldehyde reductase 1; n=18; root|Rep: A... 108 2e-22 UniRef50_Q9VHX4 Cluster: CG2767-PA; n=4; Endopterygota|Rep: CG27... 107 3e-22 UniRef50_UPI0000519CC2 Cluster: PREDICTED: similar to CG2767-PA;... 107 5e-22 UniRef50_Q68ST9 Cluster: Reductase AKOR2; n=2; Pleurotus djamor|... 106 7e-22 UniRef50_Q41399 Cluster: Chalcone reductase; n=4; eudicotyledons... 106 9e-22 UniRef50_UPI0000498F1F Cluster: oxidoreductase, aldo/keto reduct... 105 1e-21 UniRef50_Q7PLK6 Cluster: CG40064-PA; n=1; Drosophila melanogaste... 105 2e-21 UniRef50_P26690 Cluster: NAD(P)H-dependent 6'-deoxychalcone synt... 105 2e-21 UniRef50_Q2UGR1 Cluster: Aldo/keto reductase family proteins; n=... 104 3e-21 UniRef50_Q17G72 Cluster: Aldo-keto reductase; n=9; Endopterygota... 104 4e-21 UniRef50_Q5KI95 Cluster: Aldo-keto reductase, putative; n=14; Di... 104 4e-21 UniRef50_A5E082 Cluster: GCY protein; n=4; Saccharomycetales|Rep... 103 6e-21 UniRef50_P23901 Cluster: Aldose reductase; n=9; Poaceae|Rep: Ald... 103 6e-21 UniRef50_Q8SSK6 Cluster: ALDOSE REDUCTASE; n=1; Encephalitozoon ... 103 8e-21 UniRef50_Q2V420 Cluster: Uncharacterized protein At2g37770.1; n=... 102 1e-20 UniRef50_Q05KR9 Cluster: Benzil reductase; n=5; Bacillales|Rep: ... 101 3e-20 UniRef50_Q6CFG7 Cluster: Yarrowia lipolytica chromosome B of str... 101 3e-20 UniRef50_UPI0000E45E29 Cluster: PREDICTED: similar to aldose red... 100 4e-20 UniRef50_P38115 Cluster: D-arabinose dehydrogenase [NAD(P)+] hea... 100 4e-20 UniRef50_Q1IN88 Cluster: Aldehyde reductase; n=5; Bacteria|Rep: ... 100 6e-20 UniRef50_Q4PDR0 Cluster: Putative uncharacterized protein; n=1; ... 100 6e-20 UniRef50_Q4PAT5 Cluster: Putative uncharacterized protein; n=1; ... 100 6e-20 UniRef50_Q9Y020 Cluster: 3-dehydroecdysone 3beta-reductase precu... 99 8e-20 UniRef50_Q6RZX1 Cluster: Gld1; n=22; Pezizomycotina|Rep: Gld1 - ... 99 8e-20 UniRef50_P22045 Cluster: Probable reductase; n=101; cellular org... 99 8e-20 UniRef50_UPI00015B5BD7 Cluster: PREDICTED: similar to aldo-keto ... 100 1e-19 UniRef50_A2FPE2 Cluster: Oxidoreductase, aldo/keto reductase fam... 100 1e-19 UniRef50_A1D4E3 Cluster: D-xylose reductase (Xyl1), putative; n=... 100 1e-19 UniRef50_P14065 Cluster: Protein GCY; n=13; Saccharomycetales|Re... 100 1e-19 UniRef50_A6ESC0 Cluster: ARA1; n=1; unidentified eubacterium SCB... 99 2e-19 UniRef50_Q3E9M9 Cluster: Uncharacterized protein At5g01670.2; n=... 97 5e-19 UniRef50_UPI00015B40FA Cluster: PREDICTED: similar to CG2767-PA;... 97 7e-19 UniRef50_Q41E86 Cluster: 2,5-didehydrogluconate reductase; n=2; ... 97 7e-19 UniRef50_A6SI80 Cluster: Putative uncharacterized protein; n=1; ... 97 7e-19 UniRef50_Q6C2L0 Cluster: Yarrowia lipolytica chromosome F of str... 96 9e-19 UniRef50_A2QVE5 Cluster: Similarity: shows similarity to several... 96 9e-19 UniRef50_Q7PM68 Cluster: ENSANGP00000014386; n=1; Anopheles gamb... 96 1e-18 UniRef50_Q03TW0 Cluster: Aldo/keto reductase of diketogulonate r... 95 2e-18 UniRef50_P38715 Cluster: NADPH-dependent aldose reductase GRE3; ... 95 2e-18 UniRef50_Q838E0 Cluster: Oxidoreductase, aldo/keto reductase fam... 95 2e-18 UniRef50_Q1YPE5 Cluster: Aldehyde reductase; n=7; Bacteria|Rep: ... 95 2e-18 UniRef50_Q9HGY0 Cluster: Glycerol dehydrogenase; n=8; Saccharomy... 95 3e-18 UniRef50_Q0DHN0 Cluster: Os05g0456200 protein; n=2; Oryza sativa... 94 4e-18 UniRef50_Q01HB5 Cluster: OSIGBa0136O08-OSIGBa0153H12.9 protein; ... 94 4e-18 UniRef50_UPI000023D0F1 Cluster: hypothetical protein FG03517.1; ... 94 5e-18 UniRef50_A7CWF9 Cluster: Aldehyde reductase; n=2; Bacteria|Rep: ... 94 5e-18 UniRef50_A2QB88 Cluster: Contig An01c0460, complete genome. prec... 92 2e-17 UniRef50_Q5HR31 Cluster: Oxidoreductase, aldo/keto reductase fam... 92 2e-17 UniRef50_Q968S3 Cluster: Aldoketoreductase-like protein; n=1; Or... 92 2e-17 UniRef50_Q8WRT0 Cluster: 3-dehydrecdysone 3b-reductase; n=1; Tri... 92 2e-17 UniRef50_Q0CLQ2 Cluster: Putative uncharacterized protein; n=1; ... 92 2e-17 UniRef50_Q7R2T6 Cluster: GLP_291_56367_57278; n=1; Giardia lambl... 91 3e-17 UniRef50_Q24C22 Cluster: Oxidoreductase, aldo/keto reductase fam... 91 4e-17 UniRef50_Q4PHK0 Cluster: Putative uncharacterized protein; n=1; ... 91 4e-17 UniRef50_Q9ZBW7 Cluster: Putative oxidoreductase; n=2; Actinomyc... 90 6e-17 UniRef50_Q1VRG6 Cluster: YvgN; n=1; Psychroflexus torquis ATCC 7... 89 1e-16 UniRef50_Q6WGK4 Cluster: Aldose reductase; n=1; Pristionchus pac... 89 1e-16 UniRef50_Q96JD6-2 Cluster: Isoform 2 of Q96JD6 ; n=4; Catarrhini... 89 1e-16 UniRef50_Q4Q5N9 Cluster: Prostaglandin f synthase, putative; n=7... 89 1e-16 UniRef50_A3LTU8 Cluster: D-arabinose dehydrogenase; n=5; Sacchar... 89 1e-16 UniRef50_Q5V6N9 Cluster: Alcohol dehydrogenase; n=2; Halobacteri... 89 1e-16 UniRef50_UPI0000DB6EE9 Cluster: PREDICTED: similar to C35D10.6; ... 89 2e-16 UniRef50_P28475 Cluster: NADP-dependent D-sorbitol-6-phosphate d... 89 2e-16 UniRef50_A4RQH8 Cluster: Predicted protein; n=2; Ostreococcus|Re... 88 2e-16 UniRef50_Q1DLF1 Cluster: Putative uncharacterized protein; n=1; ... 88 2e-16 UniRef50_Q5FT75 Cluster: Putative 2,5-diketo-D-gluconic acid red... 88 3e-16 UniRef50_A0JX62 Cluster: 2,5-didehydrogluconate reductase; n=9; ... 88 3e-16 UniRef50_Q5TNP1 Cluster: ENSANGP00000029046; n=2; Culicidae|Rep:... 88 3e-16 UniRef50_UPI00006CD296 Cluster: oxidoreductase, aldo/keto reduct... 87 4e-16 UniRef50_Q23320 Cluster: Putative uncharacterized protein; n=4; ... 87 4e-16 UniRef50_Q18483 Cluster: Putative uncharacterized protein; n=2; ... 87 6e-16 UniRef50_Q4WF80 Cluster: Glycerol dehydrogenase (GCY1), putative... 86 1e-15 UniRef50_A7RRF6 Cluster: Predicted protein; n=2; Nematostella ve... 85 2e-15 UniRef50_Q8J0K1 Cluster: 4-dihydromethyltrisporate dehydrogenase... 85 2e-15 UniRef50_Q4P4P1 Cluster: Putative uncharacterized protein; n=1; ... 85 2e-15 UniRef50_Q013C5 Cluster: Glycerol dehydrogenase, putative; n=2; ... 85 3e-15 UniRef50_Q2H1Q3 Cluster: Putative uncharacterized protein; n=1; ... 85 3e-15 UniRef50_Q568D7 Cluster: Zgc:110366; n=7; Euteleostomi|Rep: Zgc:... 84 5e-15 UniRef50_Q1U9L6 Cluster: 2,5-didehydrogluconate reductase; n=3; ... 84 5e-15 UniRef50_A6RMS0 Cluster: Putative uncharacterized protein; n=1; ... 84 5e-15 UniRef50_Q6U5V3 Cluster: Putative uncharacterized protein; n=1; ... 83 7e-15 UniRef50_A6RKL9 Cluster: Putative uncharacterized protein; n=3; ... 83 7e-15 UniRef50_Q929C8 Cluster: Lin2349 protein; n=12; Listeria|Rep: Li... 83 1e-14 UniRef50_Q03PG5 Cluster: Aldo/keto reductase of diketogulonate r... 83 1e-14 UniRef50_A7CUW0 Cluster: 2,5-didehydrogluconate reductase; n=6; ... 83 1e-14 UniRef50_A6WDZ5 Cluster: Aldo/keto reductase; n=5; Bacteria|Rep:... 83 1e-14 UniRef50_A6QXT4 Cluster: Predicted protein; n=1; Ajellomyces cap... 83 1e-14 UniRef50_A6W8E7 Cluster: 2,5-didehydrogluconate reductase; n=3; ... 82 2e-14 UniRef50_A6NPD6 Cluster: Putative uncharacterized protein; n=3; ... 82 2e-14 UniRef50_Q7N0E4 Cluster: 2,5-diketo-D-gluconic acid reductase A;... 82 2e-14 UniRef50_Q2U219 Cluster: Aldo/keto reductase family proteins; n=... 82 2e-14 UniRef50_A5ZYE6 Cluster: Putative uncharacterized protein; n=1; ... 81 3e-14 UniRef50_A5VK30 Cluster: 2,5-didehydrogluconate reductase; n=2; ... 81 3e-14 UniRef50_A0JRJ6 Cluster: Aldo/keto reductase; n=2; Micrococcinea... 81 3e-14 UniRef50_Q235V6 Cluster: Oxidoreductase, aldo/keto reductase fam... 81 3e-14 UniRef50_O13848 Cluster: NADH/NADPH dependent indole-3-acetaldeh... 81 3e-14 UniRef50_A5AD50 Cluster: Putative uncharacterized protein; n=3; ... 81 4e-14 UniRef50_Q17568 Cluster: Putative uncharacterized protein; n=1; ... 81 4e-14 UniRef50_Q00XM4 Cluster: Aldo/keto reductase family proteins; n=... 81 5e-14 UniRef50_Q7M4N1 Cluster: Dihydrodiol dehydrogenase DD2; n=2; Hom... 81 5e-14 UniRef50_O14088 Cluster: Xylose and arabinose reductase; n=1; Sc... 81 5e-14 UniRef50_Q5FKI1 Cluster: Reductase-dehydrogenase; n=1; Lactobaci... 80 7e-14 UniRef50_Q03U37 Cluster: Aldo/keto reductase of diketogulonate r... 80 7e-14 UniRef50_Q54NR2 Cluster: Aldo-keto reductase; n=3; Dictyostelium... 80 7e-14 UniRef50_Q890A0 Cluster: Oxidoreductase; n=6; Lactobacillales|Re... 80 9e-14 UniRef50_Q6F7K7 Cluster: 2,5-diketo-D-gluconate reductase; n=20;... 80 9e-14 UniRef50_Q7XY49 Cluster: Mannose 6-phosphate reductase; n=1; Gri... 80 9e-14 UniRef50_A7TLC4 Cluster: Putative uncharacterized protein; n=1; ... 80 9e-14 UniRef50_A7D761 Cluster: Aldo/keto reductase; n=2; Halobacteriac... 80 9e-14 UniRef50_A7ALH6 Cluster: Putative uncharacterized protein; n=1; ... 79 2e-13 UniRef50_Q8F1G4 Cluster: Aldehyde reductase; n=8; Bacteria|Rep: ... 78 4e-13 UniRef50_A6LZ55 Cluster: 2,5-didehydrogluconate reductase; n=1; ... 78 4e-13 UniRef50_A2RMU6 Cluster: Oxidoreductase, aldo/keto reductase fam... 78 4e-13 UniRef50_Q5BLA6 Cluster: Zgc:110782; n=2; Danio rerio|Rep: Zgc:1... 77 5e-13 UniRef50_Q28P63 Cluster: Aldo/keto reductase; n=4; Rhodobacterac... 77 5e-13 UniRef50_A2UAH0 Cluster: Aldo/keto reductase; n=1; Bacillus coag... 77 5e-13 UniRef50_Q7NB44 Cluster: ARA1; n=3; Firmicutes|Rep: ARA1 - Mycop... 77 6e-13 UniRef50_Q043M4 Cluster: Aldo/keto reductase of diketogulonate r... 77 6e-13 UniRef50_Q07551 Cluster: NADPH-dependent alpha-keto amide reduct... 77 6e-13 UniRef50_UPI00006CCCD7 Cluster: oxidoreductase, aldo/keto reduct... 77 8e-13 UniRef50_Q5XJM7 Cluster: Zgc:101765; n=5; Eumetazoa|Rep: Zgc:101... 77 8e-13 UniRef50_Q6NII7 Cluster: Putative oxidoreductase; n=2; Corynebac... 77 8e-13 UniRef50_A1UEC5 Cluster: 2,5-didehydrogluconate reductase; n=20;... 77 8e-13 UniRef50_Q09632 Cluster: Probable oxidoreductase ZK1290.5; n=2; ... 77 8e-13 UniRef50_P47137 Cluster: Probable oxidoreductase YJR096W; n=8; S... 76 1e-12 UniRef50_Q5NLW3 Cluster: Putative oxidoreductase; n=1; Zymomonas... 76 1e-12 UniRef50_Q5T2L2 Cluster: Aldo-keto reductase family 1 member C-l... 76 1e-12 UniRef50_A5BF24 Cluster: Putative uncharacterized protein; n=1; ... 75 2e-12 UniRef50_Q927E1 Cluster: Lin2848 protein; n=13; Listeria|Rep: Li... 75 3e-12 UniRef50_Q8G7K9 Cluster: Dehydrogenase or reductase protein; n=4... 75 3e-12 UniRef50_Q8ZI40 Cluster: 2,5-diketo-D-gluconic acid reductase A;... 75 3e-12 UniRef50_A7P424 Cluster: Chromosome chr1 scaffold_5, whole genom... 74 6e-12 UniRef50_Q21274 Cluster: Putative uncharacterized protein; n=1; ... 74 6e-12 UniRef50_Q4JX70 Cluster: Putative oxidoreductase; n=1; Corynebac... 73 8e-12 UniRef50_Q4FY75 Cluster: Aldo-keto reductase-like protein; n=5; ... 73 8e-12 UniRef50_A1CAM7 Cluster: Aldo-keto reductase, putative; n=9; Dik... 73 1e-11 UniRef50_P15339 Cluster: 2,5-diketo-D-gluconic acid reductase B;... 73 1e-11 UniRef50_A5PDA8 Cluster: Putative oxidoreductase protein; n=1; E... 73 1e-11 UniRef50_Q4WUF7 Cluster: Aldo-keto reductase, putative; n=3; Pez... 72 2e-11 UniRef50_Q02198 Cluster: Morphine 6-dehydrogenase; n=5; Bacteria... 72 2e-11 UniRef50_Q5FK98 Cluster: Oxidoreductase; n=8; Lactobacillales|Re... 71 3e-11 UniRef50_Q4WP69 Cluster: Aldehyde reductase, putative; n=1; Aspe... 71 4e-11 UniRef50_Q8ET73 Cluster: 2,5-diketo-D-gluconate reductase; n=12;... 71 5e-11 UniRef50_A5DRJ6 Cluster: Putative uncharacterized protein; n=4; ... 71 5e-11 UniRef50_Q6CEJ0 Cluster: Yarrowia lipolytica chromosome B of str... 70 7e-11 UniRef50_P82125 Cluster: 1,5-anhydro-D-fructose reductase; n=1; ... 70 7e-11 UniRef50_Q9P734 Cluster: Related to 2, 5-diketo-D-gluconic acid ... 70 9e-11 UniRef50_Q9C1X5 Cluster: Xylose and arabinose reductase; n=1; Sc... 69 1e-10 UniRef50_Q83N50 Cluster: 2,5-diketo-D-gluconic acid reductase; n... 69 2e-10 UniRef50_P06632 Cluster: 2,5-diketo-D-gluconic acid reductase A;... 69 2e-10 UniRef50_A7BES9 Cluster: Putative uncharacterized protein; n=1; ... 69 2e-10 UniRef50_Q75E75 Cluster: ABL209Cp; n=1; Eremothecium gossypii|Re... 69 2e-10 UniRef50_Q5KCN9 Cluster: Putative uncharacterized protein; n=1; ... 69 2e-10 UniRef50_Q4PE96 Cluster: Putative uncharacterized protein; n=1; ... 69 2e-10 UniRef50_Q5V398 Cluster: Oxidoreductase aldo/keto reductase fami... 69 2e-10 UniRef50_Q5UX52 Cluster: Oxidoreductase aldo/keto reductase fami... 69 2e-10 UniRef50_UPI00006CA3CB Cluster: oxidoreductase, aldo/keto reduct... 68 3e-10 UniRef50_Q5KD52 Cluster: Oxidoreductase, putative; n=1; Filobasi... 68 3e-10 UniRef50_Q1Q8W8 Cluster: Aldo/keto reductase; n=1; Psychrobacter... 68 4e-10 UniRef50_Q11BF8 Cluster: Aldo/keto reductase; n=12; Bacteria|Rep... 68 4e-10 UniRef50_Q4DJ59 Cluster: Aldo/keto reductase, putative; n=2; Try... 68 4e-10 UniRef50_Q8EUH6 Cluster: Oxidoreductase; n=1; Mycoplasma penetra... 67 5e-10 UniRef50_A3UJS6 Cluster: Oxidoreductase; n=3; Alphaproteobacteri... 67 5e-10 UniRef50_Q64UK5 Cluster: Aldo/keto reductase family oxidoreducta... 67 7e-10 UniRef50_A0JRJ3 Cluster: 2,5-didehydrogluconate reductase; n=3; ... 67 7e-10 UniRef50_A6VNW9 Cluster: Aldo/keto reductase precursor; n=1; Act... 66 9e-10 UniRef50_Q6L139 Cluster: 2,5-diketo-D-gluconic acid reductase; n... 66 9e-10 UniRef50_Q9X0A2 Cluster: Oxidoreductase, aldo/keto reductase fam... 66 1e-09 UniRef50_Q76L37 Cluster: Conjugated polyketone reductase C1; n=3... 66 1e-09 UniRef50_UPI000023DF27 Cluster: hypothetical protein FG07276.1; ... 66 2e-09 UniRef50_Q03XK0 Cluster: Aldo/keto reductase of diketogulonate r... 65 2e-09 UniRef50_Q5K8C5 Cluster: Aldo-keto reductase, putative; n=1; Fil... 65 2e-09 UniRef50_A6RYK4 Cluster: Putative uncharacterized protein; n=1; ... 65 2e-09 UniRef50_P91997 Cluster: Putative uncharacterized protein; n=4; ... 65 3e-09 UniRef50_A7BA05 Cluster: Putative uncharacterized protein; n=1; ... 64 4e-09 UniRef50_Q7VG53 Cluster: Aldo-keto reductase; n=28; Bacteria|Rep... 64 5e-09 UniRef50_Q1RFP0 Cluster: 2,5-diketo-D-gluconic acid reductase A;... 64 5e-09 UniRef50_Q5KKZ8 Cluster: Aldo-keto reductase, putative; n=2; Fil... 64 5e-09 UniRef50_Q9ZUJ6 Cluster: T2K10.1 protein; n=16; core eudicotyled... 64 6e-09 UniRef50_A7RUA2 Cluster: Predicted protein; n=1; Nematostella ve... 64 6e-09 UniRef50_A7RPK2 Cluster: Predicted protein; n=1; Nematostella ve... 64 6e-09 UniRef50_Q88SL1 Cluster: Oxidoreductase; n=51; Lactobacillales|R... 63 8e-09 UniRef50_UPI000023DA24 Cluster: hypothetical protein FG10036.1; ... 63 1e-08 UniRef50_Q88TV9 Cluster: Oxidoreductase; n=4; Lactobacillus|Rep:... 63 1e-08 UniRef50_Q15NA5 Cluster: Aldo/keto reductase; n=2; Gammaproteoba... 62 2e-08 UniRef50_Q5UYI9 Cluster: Oxidoreductase; n=1; Haloarcula marismo... 62 2e-08 UniRef50_Q5FLI5 Cluster: Aldehyde reductase; n=2; Bacteria|Rep: ... 62 2e-08 UniRef50_Q76L36 Cluster: Conjugated polyketone reductase C2; n=1... 62 2e-08 UniRef50_Q0UQ60 Cluster: Putative uncharacterized protein; n=1; ... 62 2e-08 UniRef50_Q9A2X8 Cluster: Oxidoreductase, aldo/keto reductase fam... 61 4e-08 UniRef50_A0L1A2 Cluster: Aldo/keto reductase; n=8; Gammaproteoba... 61 4e-08 UniRef50_A7PNT1 Cluster: Chromosome chr8 scaffold_23, whole geno... 61 4e-08 UniRef50_A7SGW6 Cluster: Predicted protein; n=1; Nematostella ve... 61 4e-08 UniRef50_UPI00005A2CCB Cluster: PREDICTED: similar to Aldose red... 60 6e-08 UniRef50_Q1M4Z6 Cluster: Putative aldo-keto reductase/oxidase; n... 60 6e-08 UniRef50_A3WP89 Cluster: Aldo/keto reductase; n=1; Idiomarina ba... 60 6e-08 UniRef50_Q572D2 Cluster: Aldo-keto reductase, putative; n=1; Phy... 60 6e-08 UniRef50_Q0CK00 Cluster: Predicted protein; n=1; Aspergillus ter... 60 6e-08 UniRef50_Q4JCC1 Cluster: 2,5-diketo-D-gluconic acid reductase A;... 60 1e-07 UniRef50_Q03X85 Cluster: Aldo/keto reductase of diketogulonate r... 59 1e-07 UniRef50_A0AWM8 Cluster: Aldo/keto reductase; n=4; Actinomycetal... 59 2e-07 UniRef50_P91021 Cluster: Putative uncharacterized protein; n=1; ... 59 2e-07 UniRef50_Q97U17 Cluster: Oxidoreductase, aldo/keto reductase fam... 59 2e-07 UniRef50_Q9P6D3 Cluster: Related to aldo-keto reductase YPR1; n=... 58 2e-07 UniRef50_A7D6Q0 Cluster: Aldo/keto reductase; n=1; Halorubrum la... 58 2e-07 UniRef50_Q7WSY4 Cluster: Putative aldo-keto reductase; n=1; Prop... 58 3e-07 UniRef50_Q11B35 Cluster: Aldo/keto reductase; n=1; Mesorhizobium... 58 3e-07 UniRef50_Q2H7A8 Cluster: Putative uncharacterized protein; n=1; ... 58 3e-07 UniRef50_Q979I4 Cluster: Aldo / keto reductase; n=3; Archaea|Rep... 58 3e-07 UniRef50_Q89JN4 Cluster: Oxidoreductase; n=8; Rhizobiales|Rep: O... 57 5e-07 UniRef50_Q14LU6 Cluster: Putative aldo/keto reductase oxidoreduc... 57 7e-07 UniRef50_Q9USV2 Cluster: Xylose and arabinose reductase; n=2; Sc... 56 9e-07 UniRef50_Q59Z55 Cluster: Potential aldo/keto reductase; n=6; Sac... 56 9e-07 UniRef50_Q5V663 Cluster: Aldehyde reductase; n=6; Halobacteriace... 56 9e-07 UniRef50_Q5FK99 Cluster: Oxidoreductase aldo-keto reductase fami... 56 1e-06 UniRef50_Q5BC40 Cluster: Putative uncharacterized protein; n=1; ... 56 1e-06 UniRef50_A1CLD1 Cluster: Gamma-cysteine synthetase regulatory su... 56 1e-06 UniRef50_Q8DK16 Cluster: Tlr1054 protein; n=6; Cyanobacteria|Rep... 56 2e-06 UniRef50_Q7VHE1 Cluster: Putative uncharacterized protein; n=1; ... 55 2e-06 UniRef50_Q5KKC5 Cluster: Putative uncharacterized protein; n=2; ... 55 3e-06 UniRef50_Q927P9 Cluster: Lin2739 protein; n=12; Bacteria|Rep: Li... 54 4e-06 UniRef50_P70883 Cluster: AkrI; n=1; Butyrivibrio fibrisolvens|Re... 54 4e-06 UniRef50_Q89RG2 Cluster: Aldo/keto reductase; n=11; Bacteria|Rep... 54 5e-06 UniRef50_A3VHZ9 Cluster: Oxidoreductase; n=1; Rhodobacterales ba... 54 5e-06 UniRef50_A7D6I8 Cluster: Aldo/keto reductase; n=1; Halorubrum la... 54 5e-06 UniRef50_UPI0000611A01 Cluster: PREDICTED: similar to MGC80525 p... 54 7e-06 UniRef50_UPI0000447325 Cluster: PREDICTED: similar to aldo-keto ... 54 7e-06 UniRef50_Q9X265 Cluster: Oxidoreductase, aldo/keto reductase fam... 54 7e-06 UniRef50_Q6CGE9 Cluster: Similar to sp|P47137 Saccharomyces cere... 54 7e-06 UniRef50_Q9HM42 Cluster: Alcohol dehydrogenase related protein; ... 54 7e-06 UniRef50_Q4V008 Cluster: Oxidoreductase; n=4; Proteobacteria|Rep... 53 9e-06 UniRef50_Q0SFM4 Cluster: Probable 2,5-didehydrogluconate reducta... 53 9e-06 UniRef50_A0RYR0 Cluster: Oxidoreductase; n=2; cellular organisms... 53 1e-05 UniRef50_A3LWP0 Cluster: Aldo/keto reductase; n=7; Saccharomycet... 52 2e-05 UniRef50_Q2BBN7 Cluster: YvgN; n=1; Bacillus sp. NRRL B-14911|Re... 51 3e-05 UniRef50_Q8ZH36 Cluster: 2,5-diketo-D-gluconic acid reductase B;... 51 3e-05 UniRef50_A4IJ00 Cluster: LOC548351 protein; n=1; Xenopus tropica... 51 5e-05 UniRef50_Q61U89 Cluster: Putative uncharacterized protein CBG054... 51 5e-05 UniRef50_Q59ZT1 Cluster: Putative uncharacterized protein; n=1; ... 51 5e-05 UniRef50_A4YQ04 Cluster: 2,5-diketo-D-gluconate reductase B; n=1... 50 6e-05 UniRef50_A4FEB9 Cluster: 2,5-diketo-D-gluconic acid reductase; n... 50 6e-05 UniRef50_A3VRL4 Cluster: Putative uncharacterized protein; n=1; ... 50 6e-05 UniRef50_A3JU52 Cluster: 2,5-diketo-D-gluconic acid reductase A;... 50 6e-05 UniRef50_Q18903 Cluster: Putative uncharacterized protein C56G3.... 50 6e-05 UniRef50_Q8Y463 Cluster: Lmo2592 protein; n=40; Bacteria|Rep: Lm... 50 8e-05 UniRef50_Q87SA8 Cluster: Oxidoreductase Tas, aldo/keto reductase... 50 8e-05 UniRef50_A3T261 Cluster: Putative uncharacterized protein; n=1; ... 50 8e-05 UniRef50_Q33BE9 Cluster: Aldo/keto reductase, putative; n=1; Ory... 50 8e-05 UniRef50_Q5B034 Cluster: Putative uncharacterized protein; n=1; ... 50 8e-05 UniRef50_Q4P1G1 Cluster: Putative uncharacterized protein; n=1; ... 50 8e-05 UniRef50_Q9ZUX0 Cluster: Expressed protein; n=11; cellular organ... 50 1e-04 UniRef50_UPI0001556575 Cluster: PREDICTED: similar to Aldo-keto ... 49 1e-04 UniRef50_Q8EVT8 Cluster: Oxidoreductase-aldo/keto reductase fami... 49 1e-04 UniRef50_Q8EUX1 Cluster: Aldo/keto reductase family oxidoreducta... 49 1e-04 UniRef50_Q2JHT1 Cluster: Aldo/keto reductase Tas; n=25; cellular... 49 2e-04 UniRef50_Q3CZS2 Cluster: Oxidoreductase, aldo/keto reductase fam... 49 2e-04 UniRef50_Q14LA8 Cluster: Putative aldo/keto reductase oxidoreduc... 49 2e-04 UniRef50_Q872E2 Cluster: Related to gamma-glutamylcysteine synth... 49 2e-04 UniRef50_A4R217 Cluster: Putative uncharacterized protein; n=1; ... 49 2e-04 UniRef50_Q64W37 Cluster: 2,5-diketo-D-gluconic acid reductase; n... 48 4e-04 UniRef50_Q1PV10 Cluster: Putative uncharacterized protein; n=1; ... 48 4e-04 UniRef50_Q55FL2 Cluster: Putative uncharacterized protein; n=1; ... 48 4e-04 UniRef50_Q5B5R6 Cluster: Putative uncharacterized protein; n=1; ... 47 6e-04 UniRef50_Q68A33 Cluster: Aldo-keto reductase 1a; n=1; Ciona inte... 47 8e-04 UniRef50_Q11DV1 Cluster: Aldo/keto reductase; n=10; Alphaproteob... 46 0.001 UniRef50_Q7NK63 Cluster: Gll1617 protein; n=1; Gloeobacter viola... 46 0.002 UniRef50_A6PR52 Cluster: Aldo/keto reductase; n=1; Victivallis v... 46 0.002 UniRef50_Q5KQ01 Cluster: Pyridoxal reductase, putative; n=2; Fil... 46 0.002 UniRef50_Q016B0 Cluster: COG0667: Predicted oxidoreductases; n=4... 45 0.002 UniRef50_Q9V2P1 Cluster: Myo-inositol degradation; n=5; Archaea|... 45 0.002 UniRef50_P82810 Cluster: Morphine 6-dehydrogenase; n=1; Oryctola... 45 0.002 UniRef50_UPI000038E317 Cluster: hypothetical protein Faci_030017... 45 0.003 UniRef50_Q16CS5 Cluster: 2,5-diketo-D-gluconic acid reductase B,... 45 0.003 UniRef50_Q4WI64 Cluster: Aldehyde reductase, putative; n=22; Pez... 45 0.003 UniRef50_Q81RN9 Cluster: Oxidoreductase, aldo/keto reductase fam... 44 0.004 UniRef50_O94246 Cluster: Glutamate-cysteine ligase regulatory su... 44 0.004 UniRef50_P0A9T5 Cluster: Protein tas; n=88; Bacteria|Rep: Protei... 44 0.004 UniRef50_Q8EVS8 Cluster: Oxidoreductase; n=1; Mycoplasma penetra... 44 0.005 UniRef50_Q0AL14 Cluster: Aldo/keto reductase; n=1; Maricaulis ma... 44 0.005 UniRef50_A7D7K7 Cluster: Aldo/keto reductase; n=1; Halorubrum la... 44 0.005 UniRef50_Q2CAL9 Cluster: 2,5-didehydrogluconate reductase; n=2; ... 44 0.007 UniRef50_A7HEV1 Cluster: Aldo/keto reductase; n=13; Bacteria|Rep... 44 0.007 UniRef50_Q6TRS1 Cluster: Oxidoreductase; n=1; Ustilago maydis|Re... 44 0.007 UniRef50_Q09D95 Cluster: Ydhf chain A; n=1; Stigmatella aurantia... 43 0.009 UniRef50_Q60BI7 Cluster: Oxidoreductase, aldo/keto reductase fam... 43 0.012 UniRef50_Q5ZTU6 Cluster: D-xylose reductase III; n=5; Legionella... 43 0.012 UniRef50_Q966L2 Cluster: Putative uncharacterized protein; n=2; ... 43 0.012 UniRef50_Q97UV9 Cluster: Oxidoreductase; n=1; Sulfolobus solfata... 43 0.012 UniRef50_P49261 Cluster: Rho beta-crystallin; n=1; Lepidodactylu... 43 0.012 UniRef50_Q9QWA5 Cluster: Aldose reductase; n=5; Euarchontoglires... 42 0.016 UniRef50_Q8ID61 Cluster: Aldo-keto reductase, putative; n=6; Pla... 42 0.016 UniRef50_A6BIJ0 Cluster: Putative uncharacterized protein; n=1; ... 42 0.021 UniRef50_Q6NKP1 Cluster: At5g53580; n=18; cellular organisms|Rep... 42 0.021 UniRef50_Q4Q973 Cluster: Aldo/keto reductase, putative; n=3; Lei... 42 0.021 UniRef50_A2G4I3 Cluster: Oxidoreductase, aldo/keto reductase fam... 42 0.021 UniRef50_P76234 Cluster: Uncharacterized protein yeaE; n=39; Bac... 42 0.021 UniRef50_UPI0000DAE567 Cluster: hypothetical protein Rgryl_01000... 42 0.028 UniRef50_UPI00005F9591 Cluster: COG0656: Aldo/keto reductases, r... 41 0.037 UniRef50_Q6GIV4 Cluster: Aldo/keto reductase family protein; n=1... 41 0.037 UniRef50_A3U5K6 Cluster: Oxidoreductase, aldo/keto reductase fam... 41 0.037 UniRef50_Q2SL81 Cluster: Predicted oxidoreductase; n=10; Bacteri... 41 0.049 UniRef50_A5FAZ9 Cluster: Aldo/keto reductase; n=1; Flavobacteriu... 41 0.049 UniRef50_Q5KPU6 Cluster: Putative uncharacterized protein; n=2; ... 41 0.049 UniRef50_Q8ZU65 Cluster: Aldo-keto reductase, putative; n=4; The... 41 0.049 UniRef50_A3H9Y8 Cluster: Aldo/keto reductase; n=2; Caldivirga ma... 41 0.049 UniRef50_Q2SPS9 Cluster: Predicted oxidoreductase; n=5; Gammapro... 40 0.065 UniRef50_Q8G7F7 Cluster: Possible oxidoreductase of the aldo/ket... 40 0.086 UniRef50_Q8G5I8 Cluster: Possible oxidoreductase in aldo-keto re... 40 0.086 UniRef50_A7PU13 Cluster: Chromosome chr7 scaffold_31, whole geno... 40 0.086 UniRef50_A2TIR8 Cluster: Receptor for egg jelly protein 9; n=9; ... 40 0.086 UniRef50_Q1IYI7 Cluster: Aldo/keto reductase; n=3; Deinococcus g... 40 0.11 UniRef50_A1RB46 Cluster: 2,5-diketo-D-gluconate reductase; n=1; ... 40 0.11 UniRef50_P93818 Cluster: F19P19.12 protein; n=4; Arabidopsis tha... 40 0.11 UniRef50_Q94A68 Cluster: Uncharacterized oxidoreductase At1g0669... 40 0.11 UniRef50_P48507 Cluster: Glutamate--cysteine ligase regulatory s... 40 0.11 UniRef50_UPI0000D9C1BD Cluster: PREDICTED: similar to aldo-keto ... 39 0.15 UniRef50_Q9F3N3 Cluster: Putative oxidoreductase; n=3; Actinomyc... 39 0.15 UniRef50_Q8PN61 Cluster: Oxidoreductase; n=5; Proteobacteria|Rep... 39 0.15 UniRef50_Q5FJ72 Cluster: Predicted oxidoreductase; n=1; Lactobac... 39 0.15 UniRef50_A4A767 Cluster: Aldo/keto reductase/Endoribonuclease L-... 39 0.15 UniRef50_A2WWZ1 Cluster: Putative uncharacterized protein; n=1; ... 39 0.15 UniRef50_UPI0000605361 Cluster: PREDICTED: hypothetical protein;... 39 0.20 UniRef50_Q660Z5 Cluster: Aldose reductase, putative; n=3; Borrel... 39 0.20 UniRef50_Q93KW0 Cluster: Putative oxidoreductase; n=1; Streptomy... 39 0.20 UniRef50_Q3ZWR6 Cluster: Oxidoreductase, aldo reductase; n=3; De... 38 0.26 UniRef50_Q3I1P2 Cluster: Aldo-keto oxidoreductase; n=6; Bacteria... 38 0.26 UniRef50_A7B2Y7 Cluster: Putative uncharacterized protein; n=1; ... 38 0.26 UniRef50_A1WAL7 Cluster: Aldo/keto reductase; n=35; cellular org... 38 0.26 UniRef50_A1B5W4 Cluster: Aldo/keto reductase; n=1; Paracoccus de... 38 0.26 UniRef50_A7T149 Cluster: Predicted protein; n=1; Nematostella ve... 38 0.26 UniRef50_A7RWF3 Cluster: Predicted protein; n=1; Nematostella ve... 38 0.26 UniRef50_Q0D184 Cluster: Predicted protein; n=2; Trichocomaceae|... 38 0.26 UniRef50_Q28R03 Cluster: Aldo/keto reductase; n=4; Alphaproteoba... 38 0.35 UniRef50_A0Q648 Cluster: Aldo/keto reductase family protein; n=1... 38 0.35 UniRef50_Q4Q5X1 Cluster: Aldehyde reductase, putative; n=75; cel... 38 0.35 UniRef50_A3DNU7 Cluster: Aldo/keto reductase; n=3; Desulfurococc... 38 0.35 UniRef50_P40690 Cluster: Aldo-keto reductase; n=4; Piroplasmida|... 38 0.35 UniRef50_Q5V1M9 Cluster: Oxidoreductase aldo/keto reductase fami... 38 0.46 UniRef50_UPI0000DD8688 Cluster: PREDICTED: hypothetical protein;... 37 0.61 UniRef50_Q03UP2 Cluster: Aryl-alcohol dehydrogenase family enzym... 37 0.61 UniRef50_Q03BE0 Cluster: Aldo/keto reductase family enzyme; n=5;... 37 0.61 UniRef50_A7LSN6 Cluster: Putative uncharacterized protein; n=3; ... 37 0.61 UniRef50_Q7S500 Cluster: Predicted protein; n=1; Neurospora cras... 37 0.61 UniRef50_P46905 Cluster: Uncharacterized oxidoreductase yccK; n=... 37 0.61 UniRef50_Q7D001 Cluster: AGR_C_2023p; n=14; Proteobacteria|Rep: ... 37 0.81 UniRef50_Q1VSU3 Cluster: Aryl-alcohol dehydrogenase; n=1; Psychr... 37 0.81 UniRef50_Q14LU7 Cluster: Putative aldo/keto reductase n-terminal... 37 0.81 UniRef50_Q03UP0 Cluster: Aryl-alcohol dehydrogenase family enzym... 37 0.81 UniRef50_A4M6J9 Cluster: Aldo/keto reductase; n=1; Petrotoga mob... 37 0.81 UniRef50_Q8ZXA1 Cluster: Aldo-keto reductase family protein; n=3... 37 0.81 UniRef50_UPI0000DB6B5C Cluster: PREDICTED: similar to glutamate-... 36 1.1 UniRef50_Q21F89 Cluster: Aldo/keto reductase; n=1; Saccharophagu... 36 1.1 UniRef50_Q0RZJ9 Cluster: Possible transporter, MFS superfamily p... 36 1.1 UniRef50_A0QHX8 Cluster: General stress protein 69; n=2; Mycobac... 36 1.1 UniRef50_A0JZE6 Cluster: Aldo/keto reductase; n=1; Arthrobacter ... 36 1.1 UniRef50_Q54CX8 Cluster: Putative uncharacterized protein; n=1; ... 36 1.1 UniRef50_O13524 Cluster: B2-aldehyde-forming enzyme; n=1; Schizo... 36 1.1 UniRef50_Q97V56 Cluster: Dehydrogenase; n=8; Thermoprotei|Rep: D... 36 1.1 UniRef50_UPI000018356B Cluster: UPI000018356B related cluster; n... 36 1.4 UniRef50_A2UBC7 Cluster: Aldo/keto reductase; n=3; cellular orga... 36 1.4 UniRef50_Q6FW57 Cluster: Candida glabrata strain CBS138 chromoso... 36 1.4 UniRef50_A6R5B4 Cluster: NAD(P)H-dependent D-xylose reductase; n... 36 1.4 UniRef50_UPI00015BB020 Cluster: aldo/keto reductase; n=1; Ignico... 36 1.9 UniRef50_UPI0000D56933 Cluster: PREDICTED: similar to CG4919-PA;... 36 1.9 UniRef50_Q9PCQ5 Cluster: Sugar-phosphate dehydrogenase; n=23; Ba... 36 1.9 UniRef50_Q31SB1 Cluster: Putative uncharacterized protein; n=2; ... 36 1.9 UniRef50_Q1J2F9 Cluster: HRDC; n=1; Deinococcus geothermalis DSM... 36 1.9 UniRef50_Q1FGT0 Cluster: Aldo/keto reductase; n=1; Clostridium p... 36 1.9 UniRef50_Q12D62 Cluster: Aldo/keto reductase; n=12; Proteobacter... 36 1.9 UniRef50_A0VU33 Cluster: Aldo/keto reductase; n=1; Dinoroseobact... 36 1.9 UniRef50_Q9NKP7 Cluster: Putative uncharacterized protein; n=3; ... 36 1.9 UniRef50_A2FJN9 Cluster: Putative uncharacterized protein; n=4; ... 36 1.9 UniRef50_Q4P0M3 Cluster: Putative uncharacterized protein; n=1; ... 36 1.9 UniRef50_Q0CQW8 Cluster: Predicted protein; n=3; Eurotiomycetida... 36 1.9 UniRef50_A2BKU2 Cluster: Universally conserved protein; n=2; Des... 36 1.9 UniRef50_Q0SFJ5 Cluster: Aryl-alcohol dehydrogenase; n=4; Actino... 35 2.5 UniRef50_A3US12 Cluster: Oxidoreductase, aldo/keto reductase fam... 35 2.5 UniRef50_A2TW02 Cluster: Putative uncharacterized protein; n=1; ... 35 2.5 UniRef50_A0ZZI9 Cluster: Possible oxidoreductase in aldo-keto re... 35 2.5 UniRef50_A4QYA4 Cluster: Putative uncharacterized protein; n=1; ... 35 2.5 UniRef50_UPI000023E73A Cluster: hypothetical protein FG04811.1; ... 35 3.3 UniRef50_Q7WFM3 Cluster: Conserved hypothetical secreted protein... 35 3.3 UniRef50_Q3WEJ4 Cluster: Aldo/keto reductase; n=9; Bacteria|Rep:... 35 3.3 UniRef50_Q3WAH4 Cluster: ABC transporter; n=2; Frankia|Rep: ABC ... 35 3.3 UniRef50_Q6WN58 Cluster: Glutamate-cysteine ligase modifier subu... 35 3.3 UniRef50_Q54UR7 Cluster: Putative uncharacterized protein; n=2; ... 35 3.3 UniRef50_P42972 Cluster: Uncharacterized oxidoreductase ycsN; n=... 35 3.3 UniRef50_UPI000155CAC7 Cluster: PREDICTED: hypothetical protein;... 34 4.3 UniRef50_Q8YUM4 Cluster: Aldo/keto reductase; n=4; Nostocaceae|R... 34 4.3 UniRef50_Q1GLY3 Cluster: Aldo/keto reductase; n=9; Proteobacteri... 34 4.3 UniRef50_A6VXU3 Cluster: Aldo/keto reductase; n=14; Proteobacter... 34 4.3 UniRef50_Q54VZ5 Cluster: Putative glycoside hydrolase; n=1; Dict... 34 4.3 UniRef50_A3H7G3 Cluster: Aldo/keto reductase; n=2; Caldivirga ma... 34 4.3 UniRef50_UPI00015B487E Cluster: PREDICTED: similar to protease, ... 34 5.7 UniRef50_UPI0000DA3A40 Cluster: PREDICTED: hypothetical protein;... 34 5.7 UniRef50_Q88T82 Cluster: Oxidoreductase; n=18; Bacteria|Rep: Oxi... 34 5.7 UniRef50_A6VXX8 Cluster: Aldo/keto reductase; n=2; Marinomonas|R... 34 5.7 UniRef50_A2UBY5 Cluster: Plant-metabolite dehydrogenase; n=1; Ba... 34 5.7 UniRef50_Q90508 Cluster: Vitellogenin-1 precursor (Vitellogenin ... 34 5.7 UniRef50_UPI0000D55EBD Cluster: PREDICTED: similar to CG16857-PA... 33 7.5 UniRef50_Q986W6 Cluster: Mlr7180 protein; n=4; Alphaproteobacter... 33 7.5 UniRef50_A1RA11 Cluster: Oxidoreductase, aldo/keto reductase fam... 33 7.5 UniRef50_Q7QBL0 Cluster: ENSANGP00000016592; n=3; Culicidae|Rep:... 33 7.5 UniRef50_Q96JH4 Cluster: Protein KIAA1853; n=23; Tetrapoda|Rep: ... 33 7.5 UniRef50_Q4WE64 Cluster: Aldo-keto reductase (AKR), putative; n=... 33 7.5 UniRef50_UPI0000EBDB83 Cluster: PREDICTED: hypothetical protein ... 33 9.9 UniRef50_Q1YGH2 Cluster: Putative aldo/keto reductase; n=1; Aura... 33 9.9 UniRef50_Q585N8 Cluster: Putative uncharacterized protein; n=1; ... 33 9.9 UniRef50_Q2UT23 Cluster: Voltage-gated shaker-like K+ channel; n... 33 9.9 UniRef50_Q0URT8 Cluster: Putative uncharacterized protein; n=1; ... 33 9.9 UniRef50_Q97UJ7 Cluster: Oxidoreductase; n=4; Archaea|Rep: Oxido... 33 9.9 >UniRef50_UPI0000D56CE5 Cluster: PREDICTED: similar to CG6084-PA, isoform A; n=1; Tribolium castaneum|Rep: PREDICTED: similar to CG6084-PA, isoform A - Tribolium castaneum Length = 493 Score = 169 bits (412), Expect = 6e-41 Identities = 74/127 (58%), Positives = 96/127 (75%), Gaps = 1/127 (0%) Frame = +1 Query: 406 NLNVQYLDLYLIHWPQAYKEDGSLFPTD-QSGKIQFSDVDYVDTWKAMEPLVKEGLVKSI 582 NL + YLD+YL+HWP A KE SL P D ++G SDVD+VDTWKAME + ++ L KSI Sbjct: 275 NLQLDYLDVYLMHWPHALKEGPSLHPIDPKTGLFIPSDVDFVDTWKAMEKMHEKDLTKSI 334 Query: 583 GVSNFNSKQLERLLQHATVKPVVNQVECHPYLNQKRLKEFCEARGVKITXYSPLGSPDRP 762 G+SNFNS Q++RLL+ A + PV+NQ+ECHPYLNQ +L++FC RG+ +T YSPLGSP RP Sbjct: 335 GISNFNSNQIDRLLKSAKIAPVINQIECHPYLNQSKLRKFCSDRGITVTSYSPLGSPARP 394 Query: 763 WGQARRP 783 W + P Sbjct: 395 WQKPGDP 401 Score = 110 bits (265), Expect = 4e-23 Identities = 53/114 (46%), Positives = 75/114 (65%) Frame = +1 Query: 409 LNVQYLDLYLIHWPQAYKEDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGV 588 L V YLDLYLI P A K D + ++TW+AME L E L ++IG+ Sbjct: 102 LQVAYLDLYLIERPPACK-----------------DHNLIETWEAMEGLYSEKLTRAIGL 144 Query: 589 SNFNSKQLERLLQHATVKPVVNQVECHPYLNQKRLKEFCEARGVKITXYSPLGS 750 SNFNSKQ+ER+L++ T++P VNQ++CHPYLNQ +L+++C G+ + YSPLG+ Sbjct: 145 SNFNSKQIERILENCTIRPQVNQIQCHPYLNQAKLRKYCSNNGIAVISYSPLGA 198 Score = 51.6 bits (118), Expect = 3e-05 Identities = 20/45 (44%), Positives = 30/45 (66%) Frame = +2 Query: 761 PGAKPDDPQXMEDPKLKXIADRLGKTVAQVLIRYQIDXGXIVXPE 895 P KP DP + DPK+K I ++ GK+ AQ+L+RY + G +V P+ Sbjct: 394 PWQKPGDPYVINDPKIKEIGNKYGKSPAQILLRYNVQLGNVVIPK 438 >UniRef50_Q7PCV3 Cluster: ENSANGP00000031808; n=9; Endopterygota|Rep: ENSANGP00000031808 - Anopheles gambiae str. PEST Length = 316 Score = 168 bits (408), Expect = 2e-40 Identities = 74/133 (55%), Positives = 92/133 (69%), Gaps = 1/133 (0%) Frame = +1 Query: 388 CRXPWXNLNVQYLDLYLIHWPQAYKEDGSLFPTDQSGK-IQFSDVDYVDTWKAMEPLVKE 564 C+ NL + YLDLYLIHWP Y+E LFP GK FSD DYVDTW ME LV Sbjct: 97 CKTTLQNLKLDYLDLYLIHWPVGYQEGTELFPMGPDGKTFLFSDADYVDTWPEMEKLVDA 156 Query: 565 GLVKSIGVSNFNSKQLERLLQHATVKPVVNQVECHPYLNQKRLKEFCEARGVKITXYSPL 744 GLV++IGVSNFN+KQ++R+L A + P NQ+ECHPYL+Q ++ FC +G+ +T YSPL Sbjct: 157 GLVRNIGVSNFNAKQVQRVLDVARIPPATNQIECHPYLHQSKITTFCAEKGIIVTAYSPL 216 Query: 745 GSPDRPWGQARRP 783 GSP RPW +A P Sbjct: 217 GSPARPWVKADDP 229 Score = 124 bits (300), Expect = 2e-27 Identities = 58/96 (60%), Positives = 65/96 (67%) Frame = +3 Query: 114 IPVVXFXXGASXPVFGXGXWXSKPGXVXXAVKXAIDIGXRHIDCAYVYGNXXXVGXAITS 293 +P F G S P+FG G W S PG V AVK AID+G RHIDCA+VY N VG I + Sbjct: 6 VPNAIFKNGNSIPMFGLGTWNSPPGQVAQAVKDAIDVGYRHIDCAHVYQNEHEVGEGIAA 65 Query: 294 KIKEGVVTRXXLFITSKLWNTFHRPDLVRGALQEXL 401 KI EGVV R LF+TSKLWNTFHRPDLV GA + L Sbjct: 66 KIAEGVVKREDLFVTSKLWNTFHRPDLVEGACKTTL 101 Score = 48.0 bits (109), Expect = 3e-04 Identities = 21/45 (46%), Positives = 29/45 (64%) Frame = +2 Query: 761 PGAKPDDPQXMEDPKLKXIADRLGKTVAQVLIRYQIDXGXIVXPE 895 P K DDP M+D + +A + GK+ AQ+LIRYQI G +V P+ Sbjct: 222 PWVKADDPVLMDDATVGQLAKKHGKSAAQILIRYQIQLGHVVIPK 266 >UniRef50_P45376 Cluster: Aldose reductase; n=21; Bilateria|Rep: Aldose reductase - Mus musculus (Mouse) Length = 316 Score = 168 bits (408), Expect = 2e-40 Identities = 74/128 (57%), Positives = 92/128 (71%), Gaps = 2/128 (1%) Frame = +1 Query: 406 NLNVQYLDLYLIHWPQAYKEDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIG 585 +L + YLDLYLIHWP +K FP D SG + SD D+VDTW AME LV EGLVK+IG Sbjct: 99 DLQLDYLDLYLIHWPTGFKPGPDYFPLDASGNVIPSDTDFVDTWTAMEQLVDEGLVKTIG 158 Query: 586 VSNFNSKQLERLLQHATV--KPVVNQVECHPYLNQKRLKEFCEARGVKITXYSPLGSPDR 759 VSNFN Q+ER+L + KP VNQ+ECHPYL Q++L E+C ++G+ +T YSPLGSPDR Sbjct: 159 VSNFNPLQIERILNKPGLKYKPAVNQIECHPYLTQEKLIEYCHSKGIVVTAYSPLGSPDR 218 Query: 760 PWGQARRP 783 PW + P Sbjct: 219 PWAKPEDP 226 Score = 103 bits (246), Expect = 8e-21 Identities = 49/88 (55%), Positives = 55/88 (62%) Frame = +3 Query: 138 GASXPVFGXGXWXSKPGXVXXAVKXAIDIGXRHIDCAYVYGNXXXVGXAITSKIKEGVVT 317 G P G G W S PG V AVK AID+G RHIDCA VY N VG A+ K+KE VV Sbjct: 10 GTKMPTLGLGTWKSPPGQVTEAVKVAIDLGYRHIDCAQVYQNEKEVGVALQEKLKEQVVK 69 Query: 318 RXXLFITSKLWNTFHRPDLVRGALQEXL 401 R LFI SKLW TFH +V+GA Q+ L Sbjct: 70 RQDLFIVSKLWCTFHDKSMVKGAFQKTL 97 Score = 54.0 bits (124), Expect = 5e-06 Identities = 23/45 (51%), Positives = 31/45 (68%) Frame = +2 Query: 761 PGAKPDDPQXMEDPKLKXIADRLGKTVAQVLIRYQIDXGXIVXPE 895 P AKP+DP +EDP++K IA + KT AQVLIR+ I +V P+ Sbjct: 219 PWAKPEDPSLLEDPRIKAIAAKYNKTTAQVLIRFPIQRNLVVIPK 263 >UniRef50_P15121 Cluster: Aldose reductase; n=72; Eumetazoa|Rep: Aldose reductase - Homo sapiens (Human) Length = 316 Score = 163 bits (397), Expect = 4e-39 Identities = 70/134 (52%), Positives = 94/134 (70%), Gaps = 2/134 (1%) Frame = +1 Query: 388 CRXPWXNLNVQYLDLYLIHWPQAYKEDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEG 567 C+ +L + YLDLYLIHWP +K FP D+SG + SD + +DTW AME LV EG Sbjct: 93 CQKTLSDLKLDYLDLYLIHWPTGFKPGKEFFPLDESGNVVPSDTNILDTWAAMEELVDEG 152 Query: 568 LVKSIGVSNFNSKQLERLLQHATV--KPVVNQVECHPYLNQKRLKEFCEARGVKITXYSP 741 LVK+IG+SNFN Q+E +L + KP VNQ+ECHPYL Q++L ++C+++G+ +T YSP Sbjct: 153 LVKAIGISNFNHLQVEMILNKPGLKYKPAVNQIECHPYLTQEKLIQYCQSKGIVVTAYSP 212 Query: 742 LGSPDRPWGQARRP 783 LGSPDRPW + P Sbjct: 213 LGSPDRPWAKPEDP 226 Score = 106 bits (255), Expect = 7e-22 Identities = 50/88 (56%), Positives = 58/88 (65%) Frame = +3 Query: 138 GASXPVFGXGXWXSKPGXVXXAVKXAIDIGXRHIDCAYVYGNXXXVGXAITSKIKEGVVT 317 GA P+ G G W S PG V AVK AID+G RHIDCA+VY N VG AI K++E VV Sbjct: 10 GAKMPILGLGTWKSPPGQVTEAVKVAIDVGYRHIDCAHVYQNENEVGVAIQEKLREQVVK 69 Query: 318 RXXLFITSKLWNTFHRPDLVRGALQEXL 401 R LFI SKLW T+H LV+GA Q+ L Sbjct: 70 REELFIVSKLWCTYHEKGLVKGACQKTL 97 Score = 52.0 bits (119), Expect = 2e-05 Identities = 22/45 (48%), Positives = 31/45 (68%) Frame = +2 Query: 761 PGAKPDDPQXMEDPKLKXIADRLGKTVAQVLIRYQIDXGXIVXPE 895 P AKP+DP +EDP++K IA + KT AQVLIR+ + +V P+ Sbjct: 219 PWAKPEDPSLLEDPRIKAIAAKHNKTTAQVLIRFPMQRNLVVIPK 263 >UniRef50_Q8CI22 Cluster: 2310005E10Rik protein; n=30; Tetrapoda|Rep: 2310005E10Rik protein - Mus musculus (Mouse) Length = 316 Score = 155 bits (376), Expect = 1e-36 Identities = 69/128 (53%), Positives = 89/128 (69%), Gaps = 2/128 (1%) Frame = +1 Query: 406 NLNVQYLDLYLIHWPQAYKEDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIG 585 +L + YLDLYLIHWPQ ++ PTD G I S ++D W+AME LV +GLVK++G Sbjct: 99 DLKLDYLDLYLIHWPQGFQSGNVFLPTDDKGSILSSKYTFLDAWEAMEELVDQGLVKALG 158 Query: 586 VSNFNSKQLERLLQHATV--KPVVNQVECHPYLNQKRLKEFCEARGVKITXYSPLGSPDR 759 VSNFN Q+ERLL + KPV NQVECHPYL Q++L ++C ++G+ IT YSPLGSPDR Sbjct: 159 VSNFNHFQIERLLNKPGLKHKPVTNQVECHPYLTQEKLTQYCHSKGITITAYSPLGSPDR 218 Query: 760 PWGQARRP 783 P + P Sbjct: 219 PSAKPEDP 226 Score = 100 bits (240), Expect = 4e-20 Identities = 55/120 (45%), Positives = 61/120 (50%) Frame = +3 Query: 123 VXFXXGASXPVFGXGXWXSKPGXVXXAVKXAIDIGXRHIDCAYVYGNXXXVGXAITSKIK 302 V GA P+ G G W S P V AVK AID G RHIDCAYVY N VG AI KI+ Sbjct: 5 VTLLTGAKMPIVGLGTWKSPPAKVREAVKVAIDAGYRHIDCAYVYQNESEVGEAIQEKIQ 64 Query: 303 EGVVTRXXLFITSKLWNTFHRPDLVRGALQEXLXQSERSVLGSVPDTLAPGLQGRRLSLP 482 E V R LFI SKLW+TF LV+ A Q L + L G Q + LP Sbjct: 65 EKAVKREDLFIVSKLWSTFFEKSLVKKAFQNTLSDLKLDYLDLYLIHWPQGFQSGNVFLP 124 Score = 51.2 bits (117), Expect = 3e-05 Identities = 23/45 (51%), Positives = 31/45 (68%) Frame = +2 Query: 761 PGAKPDDPQXMEDPKLKXIADRLGKTVAQVLIRYQIDXGXIVXPE 895 P AKP+DP +E PK+K IA + KT AQVLIR+ I+ +V P+ Sbjct: 219 PSAKPEDPLLLEIPKIKEIAAKHKKTAAQVLIRFHIERNVVVIPK 263 >UniRef50_Q2LZ66 Cluster: GA19341-PA; n=2; Endopterygota|Rep: GA19341-PA - Drosophila pseudoobscura (Fruit fly) Length = 315 Score = 153 bits (370), Expect = 8e-36 Identities = 70/127 (55%), Positives = 85/127 (66%), Gaps = 1/127 (0%) Frame = +1 Query: 388 CRXPWXNLNVQYLDLYLIHWPQAYKEDGSLFPT-DQSGKIQFSDVDYVDTWKAMEPLVKE 564 C NL + YLDLYL+HWP AYK +L+PT +GK F D+DY+DTWKAME LV Sbjct: 94 CETSLRNLGIDYLDLYLMHWPMAYKSGDNLYPTCPDTGKAVFEDIDYLDTWKAMEDLVDS 153 Query: 565 GLVKSIGVSNFNSKQLERLLQHATVKPVVNQVECHPYLNQKRLKEFCEARGVKITXYSPL 744 GLV +IGVSNFN KQ+ RLL A +KPV+ Q+ECHPYL QK L C + +T YS L Sbjct: 154 GLVNAIGVSNFNEKQINRLLCLAKLKPVMLQIECHPYLRQKSLITLCYDNAIGVTAYSSL 213 Query: 745 GSPDRPW 765 GS P+ Sbjct: 214 GSGHTPY 220 Score = 116 bits (279), Expect = 8e-25 Identities = 54/95 (56%), Positives = 63/95 (66%) Frame = +3 Query: 117 PVVXFXXGASXPVFGXGXWXSKPGXVXXAVKXAIDIGXRHIDCAYVYGNXXXVGXAITSK 296 P G + P+ G G W S P V AVK AIDIG RH DCA++YGN VG AI K Sbjct: 4 PSFLLSSGRNMPMVGLGTWRSPPEVVAQAVKDAIDIGYRHFDCAHIYGNELHVGVAIREK 63 Query: 297 IKEGVVTRXXLFITSKLWNTFHRPDLVRGALQEXL 401 I+EG+VTR LFITSKLWNTFH+P+LVR A + L Sbjct: 64 IQEGLVTRDELFITSKLWNTFHKPELVRAACETSL 98 Score = 40.7 bits (91), Expect = 0.049 Identities = 18/44 (40%), Positives = 27/44 (61%) Frame = +2 Query: 761 PGAKPDDPQXMEDPKLKXIADRLGKTVAQVLIRYQIDXGXIVXP 892 P KP +++P + +A++ G+T AQVL+RYQ G IV P Sbjct: 219 PYEKPGSYPLLQNPIIVSVAEKYGRTPAQVLLRYQTQSGIIVIP 262 >UniRef50_P14550 Cluster: Alcohol dehydrogenase [NADP+]; n=44; Bilateria|Rep: Alcohol dehydrogenase [NADP+] - Homo sapiens (Human) Length = 325 Score = 148 bits (358), Expect = 2e-34 Identities = 63/126 (50%), Positives = 89/126 (70%) Frame = +1 Query: 406 NLNVQYLDLYLIHWPQAYKEDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIG 585 +L ++YLDLYL+HWP A++ + FP + G I + Y +TWKA+E LV +GLV+++G Sbjct: 101 DLQLEYLDLYLMHWPYAFERGDNPFPKNADGTICYDSTHYKETWKALEALVAKGLVQALG 160 Query: 586 VSNFNSKQLERLLQHATVKPVVNQVECHPYLNQKRLKEFCEARGVKITXYSPLGSPDRPW 765 +SNFNS+Q++ +L A+V+P V QVECHPYL Q L C+ARG+++T YSPLGS DR W Sbjct: 161 LSNFNSRQIDDILSVASVRPAVLQVECHPYLAQNELIAHCQARGLEVTAYSPLGSSDRAW 220 Query: 766 GQARRP 783 P Sbjct: 221 RDPDEP 226 Score = 93.5 bits (222), Expect = 7e-18 Identities = 44/94 (46%), Positives = 56/94 (59%), Gaps = 1/94 (1%) Frame = +3 Query: 123 VXFXXGASXPVFGXGXWXSKPGXVXXAVKXAIDIGXRHIDCAYVYGNXXXVGXAITSKIK 302 V G P+ G G W S+PG V AVK A+ +G RHIDCA +YGN +G A+ + Sbjct: 6 VLLHTGQKMPLIGLGTWKSEPGQVKAAVKYALSVGYRHIDCAAIYGNEPEIGEALKEDVG 65 Query: 303 EG-VVTRXXLFITSKLWNTFHRPDLVRGALQEXL 401 G V R LF+TSKLWNT H P+ V AL++ L Sbjct: 66 PGKAVPREELFVTSKLWNTKHHPEDVEPALRKTL 99 Score = 38.7 bits (86), Expect = 0.20 Identities = 14/41 (34%), Positives = 28/41 (68%) Frame = +2 Query: 773 PDDPQXMEDPKLKXIADRLGKTVAQVLIRYQIDXGXIVXPE 895 PD+P +E+P + +A++ G++ AQ+L+R+Q+ I P+ Sbjct: 223 PDEPVLLEEPVVLALAEKYGRSPAQILLRWQVQRKVICIPK 263 >UniRef50_UPI00015B56A2 Cluster: PREDICTED: similar to GA10458-PA; n=2; Nasonia vitripennis|Rep: PREDICTED: similar to GA10458-PA - Nasonia vitripennis Length = 569 Score = 146 bits (353), Expect = 9e-34 Identities = 65/127 (51%), Positives = 86/127 (67%) Frame = +1 Query: 388 CRXPWXNLNVQYLDLYLIHWPQAYKEDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEG 567 C+ NL Y+DL+L+HWP A+K +L P D +GKI+FSD DY++TWK ME ++G Sbjct: 94 CKKSLENLGFDYIDLFLVHWPFAFKSGDALTPRDAAGKIEFSDTDYLETWKGMEECKRQG 153 Query: 568 LVKSIGVSNFNSKQLERLLQHATVKPVVNQVECHPYLNQKRLKEFCEARGVKITXYSPLG 747 L +SIG+SNFNS+Q+ RLL A +KPV NQVE LNQK L EFC+ + +T +SPLG Sbjct: 154 LARSIGLSNFNSEQIARLLSSAKIKPVNNQVEVTMNLNQKPLIEFCKKHEITVTGFSPLG 213 Query: 748 SPDRPWG 768 P G Sbjct: 214 RPGNRHG 220 Score = 130 bits (314), Expect = 5e-29 Identities = 63/128 (49%), Positives = 83/128 (64%), Gaps = 1/128 (0%) Frame = +1 Query: 388 CRXPWXNLNVQYLDLYLIHWP-QAYKEDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKE 564 C+ +L + Y+DLYLIHWP + Y + SGK+ SD DY++TWK ME ++ Sbjct: 354 CKQSLNDLGLDYIDLYLIHWPIRRYFRHNK----NASGKLLLSDTDYLETWKGMEECKRQ 409 Query: 565 GLVKSIGVSNFNSKQLERLLQHATVKPVVNQVECHPYLNQKRLKEFCEARGVKITXYSPL 744 GL +SIGVSNFNS+Q+ RLL+ A +KPV NQVE LNQK L EFC+ + +T YSPL Sbjct: 410 GLARSIGVSNFNSEQITRLLEAAKIKPVNNQVEVSLKLNQKALIEFCKKHDITVTGYSPL 469 Query: 745 GSPDRPWG 768 G P +G Sbjct: 470 GRPGNRYG 477 Score = 90.2 bits (214), Expect = 6e-17 Identities = 41/96 (42%), Positives = 57/96 (59%) Frame = +3 Query: 114 IPVVXFXXGASXPVFGXGXWXSKPGXVXXAVKXAIDIGXRHIDCAYVYGNXXXVGXAITS 293 +P V F G P+ G G + SKPG V AVK AI++G RH+D A+ Y N +G AI Sbjct: 3 VPTVTFNDGYKMPMIGLGTFLSKPGEVAEAVKYAIEVGYRHVDTAFFYENEKEIGSAIRE 62 Query: 294 KIKEGVVTRXXLFITSKLWNTFHRPDLVRGALQEXL 401 KI +G + R +F+T+KLW H+ D V A ++ L Sbjct: 63 KINDGTIKREDIFVTTKLWCNSHKEDEVVPACKKSL 98 Score = 52.0 bits (119), Expect = 2e-05 Identities = 26/57 (45%), Positives = 34/57 (59%) Frame = +3 Query: 231 RHIDCAYVYGNXXXVGXAITSKIKEGVVTRXXLFITSKLWNTFHRPDLVRGALQEXL 401 RHID AY+Y N +G AI KIK+G V R LF+T+KL H+ V A ++ L Sbjct: 302 RHIDTAYLYDNEKYIGNAIREKIKDGTVKREDLFVTTKLSYYAHKESEVVPACKQSL 358 >UniRef50_Q9VTL0 Cluster: CG6083-PA; n=4; Diptera|Rep: CG6083-PA - Drosophila melanogaster (Fruit fly) Length = 322 Score = 145 bits (352), Expect = 1e-33 Identities = 69/128 (53%), Positives = 87/128 (67%), Gaps = 2/128 (1%) Frame = +1 Query: 388 CRXPWXNLNVQYLDLYLIHWPQAYKEDG-SLFPT-DQSGKIQFSDVDYVDTWKAMEPLVK 561 C NL V+YL+LYL+HWP AYK +L+PT + K F D+DYVDTW+AME LV Sbjct: 94 CETSIRNLGVKYLNLYLMHWPMAYKSGSDNLYPTCPDTNKAAFEDIDYVDTWRAMENLVD 153 Query: 562 EGLVKSIGVSNFNSKQLERLLQHATVKPVVNQVECHPYLNQKRLKEFCEARGVKITXYSP 741 EGL ++IGVSNFN +Q+ RLL A +KPVV Q+ECHPYL+QK L C + +T YS Sbjct: 154 EGLCQAIGVSNFNEQQMNRLLSVAKLKPVVLQIECHPYLSQKPLITLCYDNAIAVTAYSC 213 Query: 742 LGSPDRPW 765 LGS P+ Sbjct: 214 LGSGHTPY 221 Score = 111 bits (268), Expect = 2e-23 Identities = 51/85 (60%), Positives = 59/85 (69%) Frame = +3 Query: 138 GASXPVFGXGXWXSKPGXVXXAVKXAIDIGXRHIDCAYVYGNXXXVGXAITSKIKEGVVT 317 G + P+ G G W S P V AVK AIDIG RH DCA++YGN VG A+ K+ EGVVT Sbjct: 11 GKNMPMLGLGTWRSPPEVVTQAVKDAIDIGYRHFDCAHIYGNEAQVGAALREKMDEGVVT 70 Query: 318 RXXLFITSKLWNTFHRPDLVRGALQ 392 R LFITSKLWNT H+PDLVR A + Sbjct: 71 RDELFITSKLWNTHHKPDLVRPACE 95 Score = 36.3 bits (80), Expect = 1.1 Identities = 17/44 (38%), Positives = 25/44 (56%) Frame = +2 Query: 761 PGAKPDDPQXMEDPKLKXIADRLGKTVAQVLIRYQIDXGXIVXP 892 P KP ++ P + IA++ +T AQVL+R+Q G IV P Sbjct: 220 PYEKPGAYPLLQHPTILAIAEKYERTAAQVLLRFQTQSGIIVIP 263 >UniRef50_UPI0000588153 Cluster: PREDICTED: hypothetical protein; n=1; Strongylocentrotus purpuratus|Rep: PREDICTED: hypothetical protein - Strongylocentrotus purpuratus Length = 333 Score = 143 bits (347), Expect = 5e-33 Identities = 66/134 (49%), Positives = 88/134 (65%), Gaps = 2/134 (1%) Frame = +1 Query: 406 NLNVQYLDLYLIHWPQAYKEDGS--LFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKS 579 +L + Y+DLY++HWP ++ G +FP ++G I +SDV Y++TW AME LVK G KS Sbjct: 99 DLQLDYIDLYIMHWPLGFQNLGPTVMFPRTETGDIVYSDVHYLETWSAMEDLVKTGKCKS 158 Query: 580 IGVSNFNSKQLERLLQHATVKPVVNQVECHPYLNQKRLKEFCEARGVKITXYSPLGSPDR 759 +G+SNFNSKQL+ +LQH+TV P V QVE HP+L Q L FC R V ++ YSPLG DR Sbjct: 159 LGLSNFNSKQLDDVLQHSTVPPSVLQVESHPFLPQVELLNFCRERSVVVSAYSPLGCGDR 218 Query: 760 PWGQARRPPXHGGP 801 W + P P Sbjct: 219 AWKLSGEPSIFDDP 232 Score = 74.5 bits (175), Expect = 3e-12 Identities = 33/80 (41%), Positives = 45/80 (56%) Frame = +3 Query: 123 VXFXXGASXPVFGXGXWXSKPGXVXXAVKXAIDIGXRHIDCAYVYGNXXXVGXAITSKIK 302 V G + P+ G G W K V A+ A+D G RH DCA +YGN VG A+ ++ Sbjct: 5 VTLPSGHAMPLVGLGTWKLKADEVAGAIGAAVDAGYRHFDCALIYGNEKEVGVALREAMQ 64 Query: 303 EGVVTRXXLFITSKLWNTFH 362 + R +FIT+K+WNTFH Sbjct: 65 RLGLKREDVFITTKVWNTFH 84 Score = 40.3 bits (90), Expect = 0.065 Identities = 18/39 (46%), Positives = 25/39 (64%) Frame = +2 Query: 779 DPQXMEDPKLKXIADRLGKTVAQVLIRYQIDXGXIVXPE 895 +P +DP L IA RL K++AQV IR+Q+ G V P+ Sbjct: 225 EPSIFDDPGLLKIAQRLRKSIAQVAIRFQVQRGIPVIPK 263 >UniRef50_Q9NAI5 Cluster: Putative uncharacterized protein; n=3; Caenorhabditis|Rep: Putative uncharacterized protein - Caenorhabditis elegans Length = 316 Score = 141 bits (341), Expect = 3e-32 Identities = 59/116 (50%), Positives = 81/116 (69%) Frame = +1 Query: 406 NLNVQYLDLYLIHWPQAYKEDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIG 585 +L + Y+DL LIHWPQ Y E LFP ++GK+++SDVDY++TWKA E K G +SIG Sbjct: 99 DLQLSYVDLMLIHWPQGYAEGAELFPAGENGKMRYSDVDYLETWKAFEAAQKAGKCRSIG 158 Query: 586 VSNFNSKQLERLLQHATVKPVVNQVECHPYLNQKRLKEFCEARGVKITXYSPLGSP 753 +SNF Q++R+ A VKP QVE HPY Q +L+EFC+ +G+ + YSPLG+P Sbjct: 159 LSNFTHSQIQRVWDAAEVKPACLQVELHPYFTQVKLREFCKEKGIVVVGYSPLGNP 214 Score = 92.3 bits (219), Expect = 2e-17 Identities = 42/75 (56%), Positives = 48/75 (64%) Frame = +3 Query: 138 GASXPVFGXGXWXSKPGXVXXAVKXAIDIGXRHIDCAYVYGNXXXVGXAITSKIKEGVVT 317 G S P G G W SKPG V A+K A+ G RHIDCA+VY N VG A+ + EG V Sbjct: 10 GYSIPAIGLGTWQSKPGEVAAAIKTAVAAGYRHIDCAHVYQNQKEVGEALKEILDEGKVK 69 Query: 318 RXXLFITSKLWNTFH 362 R LFITSK+WNTFH Sbjct: 70 REELFITSKVWNTFH 84 >UniRef50_UPI00015B56A3 Cluster: PREDICTED: similar to aldo-keto reductase; n=1; Nasonia vitripennis|Rep: PREDICTED: similar to aldo-keto reductase - Nasonia vitripennis Length = 321 Score = 136 bits (330), Expect = 5e-31 Identities = 58/124 (46%), Positives = 83/124 (66%) Frame = +1 Query: 388 CRXPWXNLNVQYLDLYLIHWPQAYKEDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEG 567 C+ L + Y+DLYL+HWP +Y + +VDY++TW+ ME +K G Sbjct: 98 CKRSLKKLGLGYIDLYLVHWPFSYPILYQYIVLPTYNAVTLDEVDYIETWRGMEECIKLG 157 Query: 568 LVKSIGVSNFNSKQLERLLQHATVKPVVNQVECHPYLNQKRLKEFCEARGVKITXYSPLG 747 L +SIGVSNFNS+QL RLL+ A++KPV+NQ+E H LNQK+L+EFC ++ + +T YSP G Sbjct: 158 LTRSIGVSNFNSQQLTRLLESASIKPVMNQIELHINLNQKKLREFCASKSIAVTGYSPFG 217 Query: 748 SPDR 759 +P R Sbjct: 218 APGR 221 Score = 86.2 bits (204), Expect = 1e-15 Identities = 43/102 (42%), Positives = 55/102 (53%), Gaps = 2/102 (1%) Frame = +3 Query: 102 MAPXIPVVXFXXGASXPVFGXGXWX--SKPGXVXXAVKXAIDIGXRHIDCAYVYGNXXXV 275 M+P + + G PV G G W + P V AVK AID G RH DCA YGN + Sbjct: 1 MSPKVDEITLSDGNKVPVLGLGTWQGGNDPDEVENAVKLAIDAGYRHFDCASFYGNEAEI 60 Query: 276 GXAITSKIKEGVVTRXXLFITSKLWNTFHRPDLVRGALQEXL 401 G AI KI +GVV R LF+ +K+WN + +LV A + L Sbjct: 61 GKAIQEKIDQGVVKREDLFVVTKVWNDERKQELVVAACKRSL 102 Score = 33.1 bits (72), Expect = 9.9 Identities = 14/35 (40%), Positives = 22/35 (62%) Frame = +2 Query: 791 MEDPKLKXIADRLGKTVAQVLIRYQIDXGXIVXPE 895 ++ P + IA + KT AQ+++RY ID G I P+ Sbjct: 234 LQSPVITGIAKKYNKTNAQIVLRYVIDIGAIPIPK 268 >UniRef50_Q17DN1 Cluster: Aldo-keto reductase; n=1; Aedes aegypti|Rep: Aldo-keto reductase - Aedes aegypti (Yellowfever mosquito) Length = 284 Score = 136 bits (328), Expect = 9e-31 Identities = 60/95 (63%), Positives = 74/95 (77%) Frame = +1 Query: 472 SLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQHATVKPVV 651 +L P D GK+QFSDVDY+DTWKAME L+K G VKSIGVSNFNS+Q+ RLL +KPV Sbjct: 89 NLMPYDADGKLQFSDVDYIDTWKAMEKLLKTGKVKSIGVSNFNSEQITRLLAECEIKPVT 148 Query: 652 NQVECHPYLNQKRLKEFCEARGVKITXYSPLGSPD 756 NQVEC+P LNQ++L EFC+ + +T YSPLG P+ Sbjct: 149 NQVECNPSLNQRKLTEFCKNLDITLTAYSPLGRPN 183 Score = 87.8 bits (208), Expect = 3e-16 Identities = 44/87 (50%), Positives = 52/87 (59%), Gaps = 2/87 (2%) Frame = +3 Query: 102 MAPXIPVVXFXXGASXPVFGXGXWXSKPGXVXXAVKXAIDIGXRHIDCAYVYGNXXXVGX 281 M+P P+V G PV G G W SK G A+K AID G RHID AY Y N VG Sbjct: 1 MSPKAPMVKLNNGLEMPVLGLGTWLSKEGEGVEAIKAAIDAGYRHIDTAYFYQNEKEVGE 60 Query: 282 AITSKIKEGVVTRXXLFITSKL--WNT 356 AI +KI+EGVV R LF+T+K W+T Sbjct: 61 AIRAKIEEGVVCREDLFVTTKFIDWDT 87 Score = 35.9 bits (79), Expect = 1.4 Identities = 18/52 (34%), Positives = 27/52 (51%) Frame = +2 Query: 740 PSARRTDPGAKPDDPQXMEDPKLKXIADRLGKTVAQVLIRYQIDXGXIVXPE 895 P+ DP P ++DPK+ I + KT QV++RY +D G I P+ Sbjct: 182 PNYYEKDPDNMPKPA--LDDPKVIEIGKKYNKTSGQVILRYLVDIGTIPIPK 231 >UniRef50_Q7QK25 Cluster: ENSANGP00000019775; n=2; Anopheles gambiae str. PEST|Rep: ENSANGP00000019775 - Anopheles gambiae str. PEST Length = 319 Score = 135 bits (326), Expect = 2e-30 Identities = 66/128 (51%), Positives = 90/128 (70%), Gaps = 5/128 (3%) Frame = +1 Query: 391 RXPWXNLNVQYLDLYLIHWPQAYKEDG----SLFPTDQSGKIQFSDVDYVDTWKAMEPLV 558 R + L++ Y+DL+L+H P + G + P D +G + FSDVDYV+TWKAME LV Sbjct: 97 RRSFDMLDIGYIDLFLMHSPMGVQFSGYEYADMQPKDAAGNMLFSDVDYVETWKAMEKLV 156 Query: 559 KEG-LVKSIGVSNFNSKQLERLLQHATVKPVVNQVECHPYLNQKRLKEFCEARGVKITXY 735 G V+SIG+SNFNS+Q+ER+LQ ATVKPV NQVE +P +Q++L FC+ARG+ +T Y Sbjct: 157 TAGGRVRSIGLSNFNSEQIERILQIATVKPVNNQVEANPGYDQRKLIAFCQARGITVTAY 216 Query: 736 SPLGSPDR 759 P+G P R Sbjct: 217 GPMGRPHR 224 Score = 95.9 bits (228), Expect = 1e-18 Identities = 44/97 (45%), Positives = 58/97 (59%) Frame = +3 Query: 102 MAPXIPVVXFXXGASXPVFGXGXWXSKPGXVXXAVKXAIDIGXRHIDCAYVYGNXXXVGX 281 M+ +P V F G PV G G + ++ G VK AID+G RHID A++Y N +G Sbjct: 1 MSTQVPTVRFSNGYEIPVLGYGTYLAQKGQCVELVKKAIDLGYRHIDTAFLYENEVEIGQ 60 Query: 282 AITSKIKEGVVTRXXLFITSKLWNTFHRPDLVRGALQ 392 AI KI EGV+ R +F+T+KLWNTFH P V A + Sbjct: 61 AIRDKIAEGVIRREDVFVTTKLWNTFHDPQHVEEAFR 97 Score = 36.7 bits (81), Expect = 0.81 Identities = 16/34 (47%), Positives = 22/34 (64%) Frame = +2 Query: 791 MEDPKLKXIADRLGKTVAQVLIRYQIDXGXIVXP 892 ++DPK+ I + GKT QV++RY ID G I P Sbjct: 233 LDDPKVLEIGRKYGKTGGQVILRYLIDIGTIPIP 266 >UniRef50_A5KSS3 Cluster: Aldehyde reductase; n=1; candidate division TM7 genomosp. GTL1|Rep: Aldehyde reductase - candidate division TM7 genomosp. GTL1 Length = 299 Score = 133 bits (321), Expect = 7e-30 Identities = 60/127 (47%), Positives = 83/127 (65%) Frame = +1 Query: 382 VPCRXPWXNLNVQYLDLYLIHWPQAYKEDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVK 561 V CR +L + YLDLYLIHW A++ +L P D G +FS + +TW+AME LV+ Sbjct: 90 VACRKTLNDLGLDYLDLYLIHWGVAFEHGDNLEPLDDDGVAKFSFISMKETWQAMEELVE 149 Query: 562 EGLVKSIGVSNFNSKQLERLLQHATVKPVVNQVECHPYLNQKRLKEFCEARGVKITXYSP 741 +GLVKS+GV+NF + L LL +A +KP V+Q+E HPYL Q L FC ++ + +T YSP Sbjct: 150 QGLVKSMGVANFTAPMLLDLLSYAKIKPAVHQIELHPYLAQNDLVAFCYSQNIAVTAYSP 209 Query: 742 LGSPDRP 762 GS + P Sbjct: 210 FGSTEAP 216 Score = 78.2 bits (184), Expect = 3e-13 Identities = 36/71 (50%), Positives = 41/71 (57%) Frame = +3 Query: 150 PVFGXGXWXSKPGXVXXAVKXAIDIGXRHIDCAYVYGNXXXVGXAITSKIKEGVVTRXXL 329 P+ G G W G V+ AI G RHIDCA +YGN VG I I +GVV R L Sbjct: 13 PLLGYGTWELPTGTTADLVETAIKAGYRHIDCAMIYGNEKEVGEGIRRTIDQGVVKREDL 72 Query: 330 FITSKLWNTFH 362 F+TSKLWNT H Sbjct: 73 FVTSKLWNTDH 83 Score = 33.9 bits (74), Expect = 5.7 Identities = 15/34 (44%), Positives = 21/34 (61%) Frame = +2 Query: 791 MEDPKLKXIADRLGKTVAQVLIRYQIDXGXIVXP 892 + DP +K +A LGKT AQVL+R+ + V P Sbjct: 218 LTDPTVKEVAKGLGKTPAQVLLRWAVQRNTSVIP 251 >UniRef50_A7SIT3 Cluster: Predicted protein; n=1; Nematostella vectensis|Rep: Predicted protein - Nematostella vectensis Length = 323 Score = 132 bits (319), Expect = 1e-29 Identities = 62/124 (50%), Positives = 87/124 (70%) Frame = +1 Query: 388 CRXPWXNLNVQYLDLYLIHWPQAYKEDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEG 567 C+ NL + YLDLYLIH P A+K+ L + G I ++ +TW+AME LV +G Sbjct: 96 CQATLKNLQLDYLDLYLIHIPVAFKKGVRLPHSIAEGIIGYTPEGVQNTWQAMEGLVAKG 155 Query: 568 LVKSIGVSNFNSKQLERLLQHATVKPVVNQVECHPYLNQKRLKEFCEARGVKITXYSPLG 747 L K+IGVSNF+ K+L +LL+ A++ P NQVE HPYL Q++LKEFC+++G+ +T YSPLG Sbjct: 156 LCKAIGVSNFSVKRLNKLLETASIVPACNQVELHPYLPQEKLKEFCDSKGILLTAYSPLG 215 Query: 748 SPDR 759 +P R Sbjct: 216 NPGR 219 Score = 87.4 bits (207), Expect = 4e-16 Identities = 42/88 (47%), Positives = 51/88 (57%) Frame = +3 Query: 138 GASXPVFGXGXWXSKPGXVXXAVKXAIDIGXRHIDCAYVYGNXXXVGXAITSKIKEGVVT 317 GAS P G W S V AV+ AI++G RHIDCA +YGN +G A++ + EG V Sbjct: 13 GASIPAMALGTWQSSKEEVGNAVRLAIELGYRHIDCAEIYGNEGEIGEALSEVLTEGKVK 72 Query: 318 RXXLFITSKLWNTFHRPDLVRGALQEXL 401 R LF+TSKLW H PD V A Q L Sbjct: 73 REELFVTSKLWCDSHHPDDVLPACQATL 100 >UniRef50_Q0VGY1 Cluster: 3-alpha-hydroxysteroid dehydrogenase; n=13; Tetrapoda|Rep: 3-alpha-hydroxysteroid dehydrogenase - Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) Length = 324 Score = 132 bits (318), Expect = 2e-29 Identities = 63/129 (48%), Positives = 84/129 (65%), Gaps = 3/129 (2%) Frame = +1 Query: 406 NLNVQYLDLYLIHWPQAYKEDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIG 585 +L + Y+DL++IH P +K LFP D++GK + + D DTWKA+E GLV+SIG Sbjct: 106 DLQLDYMDLFIIHMPMEFKPGDDLFPADENGKFIYHNTDLRDTWKALEKCKDAGLVRSIG 165 Query: 586 VSNFNSKQLERLLQHATV--KPVVNQVECHPYLNQKRLKEFCEARGVKITXYSPLGSP-D 756 VSNFN KQLE +L + KPV NQVECH YLNQ +L EFC+++ + + YS LGS D Sbjct: 166 VSNFNHKQLELILNMPGLKYKPVCNQVECHVYLNQSKLLEFCKSKDIVLVGYSVLGSSRD 225 Query: 757 RPWGQARRP 783 W +A P Sbjct: 226 ERWIEASTP 234 Score = 83.0 bits (196), Expect = 9e-15 Identities = 42/96 (43%), Positives = 53/96 (55%), Gaps = 3/96 (3%) Frame = +3 Query: 123 VXFXXGASXPVFGXGXWXSKP---GXVXXAVKXAIDIGXRHIDCAYVYGNXXXVGXAITS 293 V G PV G G + K AID+G RHIDCA++YGN VG AI + Sbjct: 9 VELNDGHKMPVIGFGTYAPPKFPKSLAEEGTKVAIDVGYRHIDCAFLYGNEEEVGRAIRA 68 Query: 294 KIKEGVVTRXXLFITSKLWNTFHRPDLVRGALQEXL 401 KI +G V R +F T KLW+T H P+ VR AL++ L Sbjct: 69 KIADGTVKREDVFYTGKLWSTSHTPERVRPALEKSL 104 Score = 33.9 bits (74), Expect = 5.7 Identities = 15/35 (42%), Positives = 21/35 (60%) Frame = +2 Query: 782 PQXMEDPKLKXIADRLGKTVAQVLIRYQIDXGXIV 886 P +EDP L IA + +T AQV +RY + G +V Sbjct: 234 PVLLEDPALTEIAKKHNRTPAQVAMRYHLQRGVVV 268 >UniRef50_A2QBD7 Cluster: Catalytic activity: an alcohol + NADP(+) <=> an aldehyde + NADPH; n=4; Trichocomaceae|Rep: Catalytic activity: an alcohol + NADP(+) <=> an aldehyde + NADPH - Aspergillus niger Length = 323 Score = 132 bits (318), Expect = 2e-29 Identities = 57/115 (49%), Positives = 80/115 (69%) Frame = +1 Query: 406 NLNVQYLDLYLIHWPQAYKEDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIG 585 +L V YLDLYL+HWP A+K FP + G +++DY+ T++AME L+ G V++IG Sbjct: 97 DLGVAYLDLYLMHWPCAFKGGDKWFPLNDDGVFDLANIDYITTYRAMEKLLATGKVRAIG 156 Query: 586 VSNFNSKQLERLLQHATVKPVVNQVECHPYLNQKRLKEFCEARGVKITXYSPLGS 750 VSNFN ++LE LL +V P VNQ+E HPYL Q L +FC+++G+ I YSPLG+ Sbjct: 157 VSNFNIRRLEELLGQVSVVPAVNQIEAHPYLQQPDLLQFCQSKGILIEAYSPLGN 211 Score = 75.8 bits (178), Expect = 1e-12 Identities = 42/88 (47%), Positives = 49/88 (55%) Frame = +3 Query: 138 GASXPVFGXGXWXSKPGXVXXAVKXAIDIGXRHIDCAYVYGNXXXVGXAITSKIKEGVVT 317 GA P G G W +KP V AV+ A+ G RHIDCA +Y N VG I K G V Sbjct: 12 GAKIPAVGFGTWQAKPLEVENAVEVALREGYRHIDCAAIYRNETEVGNGIR---KSG-VP 67 Query: 318 RXXLFITSKLWNTFHRPDLVRGALQEXL 401 R +FIT KLWNT H P+ V AL + L Sbjct: 68 REEIFITGKLWNTKHAPEDVEPALDKTL 95 >UniRef50_Q17DN0 Cluster: Aldo-keto reductase; n=5; Culicidae|Rep: Aldo-keto reductase - Aedes aegypti (Yellowfever mosquito) Length = 324 Score = 131 bits (317), Expect = 2e-29 Identities = 64/120 (53%), Positives = 81/120 (67%), Gaps = 4/120 (3%) Frame = +1 Query: 406 NLNVQYLDLYLIHWPQAYKEDG----SLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLV 573 +L + Y+DL+LIH P Y+ +G P D +G + SD DYVDTWKAME L++ G V Sbjct: 103 HLGLDYVDLFLIHMPFGYEFNGWDPEKRTPLDDNGNVLCSDDDYVDTWKAMEKLLESGRV 162 Query: 574 KSIGVSNFNSKQLERLLQHATVKPVVNQVECHPYLNQKRLKEFCEARGVKITXYSPLGSP 753 SIGVSNFNS+QLER+L + VKPV NQVEC +NQK L EFC R + +T +SP G P Sbjct: 163 HSIGVSNFNSEQLERILANCRVKPVTNQVECSARINQKLLIEFCMERDIVVTAHSPFGRP 222 Score = 94.7 bits (225), Expect = 3e-18 Identities = 51/99 (51%), Positives = 56/99 (56%) Frame = +3 Query: 105 APXIPVVXFXXGASXPVFGXGXWXSKPGXVXXAVKXAIDIGXRHIDCAYVYGNXXXVGXA 284 A IP V G P G G SK AV AID G RHID AY Y N VG A Sbjct: 3 ARFIPTVKLNNGLEMPAIGLGTSMSKGDECCKAVMTAIDEGFRHIDTAYNYRNEDVVGRA 62 Query: 285 ITSKIKEGVVTRXXLFITSKLWNTFHRPDLVRGALQEXL 401 I +KI+EGVVTR LF+T+KLWNTFH PD V A + L Sbjct: 63 IRAKIEEGVVTREELFVTTKLWNTFHHPDHVPMAFGKSL 101 >UniRef50_Q7ZWA4 Cluster: Zgc:56622; n=6; cellular organisms|Rep: Zgc:56622 - Danio rerio (Zebrafish) (Brachydanio rerio) Length = 289 Score = 131 bits (316), Expect = 3e-29 Identities = 61/120 (50%), Positives = 83/120 (69%), Gaps = 1/120 (0%) Frame = +1 Query: 406 NLNVQYLDLYLIHWPQAYKEDGS-LFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSI 582 +L + YLD YL+H+P K+ G LFP ++ GKI +D+DYVD W+ ME L G VKSI Sbjct: 73 DLQLDYLDQYLVHFPVGLKKVGDELFP-ERDGKILTTDIDYVDVWRGMEALKATGKVKSI 131 Query: 583 GVSNFNSKQLERLLQHATVKPVVNQVECHPYLNQKRLKEFCEARGVKITXYSPLGSPDRP 762 GVSNF +Q++RLL A + P VNQVE HPYL Q L ++C+++ + +T +SP GSP RP Sbjct: 132 GVSNFTMEQIDRLLSVAKIPPAVNQVELHPYLVQSDLIDYCKSKNIALTAHSPFGSPGRP 191 Score = 63.7 bits (148), Expect = 6e-09 Identities = 28/57 (49%), Positives = 37/57 (64%) Frame = +3 Query: 201 AVKXAIDIGXRHIDCAYVYGNXXXVGXAITSKIKEGVVTRXXLFITSKLWNTFHRPD 371 A + AI G RHID A+ Y N VG AI +KI++G++ R +FI SKLW T H P+ Sbjct: 5 ACEAAIAAGYRHIDTAFCYRNEVDVGMAIQNKIQQGIIRRQDMFIVSKLWGTHHAPE 61 >UniRef50_Q96UH3 Cluster: Aldehyde reductase; n=13; Pezizomycotina|Rep: Aldehyde reductase - Coccidioides posadasii Length = 314 Score = 131 bits (316), Expect = 3e-29 Identities = 56/125 (44%), Positives = 82/125 (65%) Frame = +1 Query: 406 NLNVQYLDLYLIHWPQAYKEDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIG 585 NL + YLDLYL+HWP A+ +FP D G + D+DYVDT+KAME LVK G K+IG Sbjct: 97 NLEIDYLDLYLMHWPAAFAPGDDMFPKDSQGNSKTVDIDYVDTYKAMEKLVKSGKTKAIG 156 Query: 586 VSNFNSKQLERLLQHATVKPVVNQVECHPYLNQKRLKEFCEARGVKITXYSPLGSPDRPW 765 +SNF+ ++ERLL+ ++ P V Q+E HP+L Q E+ +++G+ +T YS LG+ + + Sbjct: 157 ISNFSKGEMERLLESCSIVPAVMQMELHPWLQQNDFVEWLKSKGIHVTQYSSLGNQNEVY 216 Query: 766 GQARR 780 R Sbjct: 217 SGRER 221 Score = 63.7 bits (148), Expect = 6e-09 Identities = 41/110 (37%), Positives = 50/110 (45%), Gaps = 4/110 (3%) Frame = +3 Query: 138 GASXPVFGXGXWXSKPGXVXXAVKXAIDIGXRHIDCAYVYGNXXXVGXAITSKIKEGVVT 317 G P G G W + AV A+ G RHID A VYG +G A+ ++ Sbjct: 13 GEDIPAIGFGTWQDENAQ-EDAVLTALSAGYRHIDTAAVYGTEKAIGRALA----RSRLS 67 Query: 318 RXXLFITSKLWNTFHRPDLVRGALQEXLXQSERSVLGSV----PDTLAPG 455 R LFITSKLWN HRP+ V A+ + L E L P APG Sbjct: 68 RDELFITSKLWNNKHRPEDVEQAIDQSLKNLEIDYLDLYLMHWPAAFAPG 117 >UniRef50_Q5BKE9 Cluster: LOC594893 protein; n=5; Xenopus tropicalis|Rep: LOC594893 protein - Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) Length = 345 Score = 128 bits (310), Expect = 1e-28 Identities = 58/117 (49%), Positives = 78/117 (66%), Gaps = 2/117 (1%) Frame = +1 Query: 409 LNVQYLDLYLIHWPQAYKEDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGV 588 L + Y+DLYLIH P ++K LFP ++ G F D + TW+A+E GLVKSIGV Sbjct: 128 LQMDYVDLYLIHMPMSFKPAEELFPKNEDGTCAFDQPDLLQTWQALEECRDAGLVKSIGV 187 Query: 589 SNFNSKQLERLLQHATV--KPVVNQVECHPYLNQKRLKEFCEARGVKITXYSPLGSP 753 SNFN +QLE +L + KPV NQ+ECHPYLNQK++ EFC+++ + + Y LGSP Sbjct: 188 SNFNRRQLEMILNKPGLKYKPVCNQIECHPYLNQKQMLEFCKSKDIVVVAYGVLGSP 244 Score = 77.8 bits (183), Expect = 4e-13 Identities = 35/70 (50%), Positives = 46/70 (65%) Frame = +3 Query: 192 VXXAVKXAIDIGXRHIDCAYVYGNXXXVGXAITSKIKEGVVTRXXLFITSKLWNTFHRPD 371 V A K A+D+G RH+D A++Y + VG A K +G + R LF TSKLWNTFH+P Sbjct: 56 VRVATKMALDLGYRHVDGAFLYSSETGVGQAFREKFADGTLKREDLFYTSKLWNTFHQPH 115 Query: 372 LVRGALQEXL 401 LVR AL++ L Sbjct: 116 LVRPALEKTL 125 >UniRef50_UPI0000E4A7CE Cluster: PREDICTED: similar to LOC553452 protein; n=6; Strongylocentrotus purpuratus|Rep: PREDICTED: similar to LOC553452 protein - Strongylocentrotus purpuratus Length = 321 Score = 128 bits (309), Expect = 2e-28 Identities = 62/126 (49%), Positives = 82/126 (65%), Gaps = 2/126 (1%) Frame = +1 Query: 388 CRXPWXNLNVQYLDLYLIHWPQAYKEDGSLFPTDQSGKIQFSD-VDYVDTWKAMEPLVKE 564 CR +L + YLDL+LIH P + FP D +G D +DYVDTW+ ME LV + Sbjct: 96 CRQSLSDLGLAYLDLFLIHCPTSAVGGKGPFPMDDNGLFIGDDTIDYVDTWRIMESLVDK 155 Query: 565 GLVKSIGVSNFNSKQLERLLQHATVKPVVN-QVECHPYLNQKRLKEFCEARGVKITXYSP 741 GLV++IGVSNF Q++R+L P+ N QVECHP+L Q L EFC+ +G+ +T YSP Sbjct: 156 GLVRAIGVSNFTVAQIQRVLDLPPKYPIANVQVECHPFLAQNELIEFCKKQGITVTAYSP 215 Query: 742 LGSPDR 759 LGSP+R Sbjct: 216 LGSPER 221 Score = 79.4 bits (187), Expect = 1e-13 Identities = 38/88 (43%), Positives = 49/88 (55%) Frame = +3 Query: 138 GASXPVFGXGXWXSKPGXVXXAVKXAIDIGXRHIDCAYVYGNXXXVGXAITSKIKEGVVT 317 G P+ G G W KP V ++ AID G RHID A +YGN VG I +KI +G + Sbjct: 13 GRKLPLLGFGTWQIKPEEVGRVIETAIDCGYRHIDEASLYGNEKGVGDGIKAKIDDGTIK 72 Query: 318 RXXLFITSKLWNTFHRPDLVRGALQEXL 401 R LF+TSKLW T P V + ++ L Sbjct: 73 REDLFVTSKLWVTDSHPSRVEPSCRQSL 100 Score = 41.1 bits (92), Expect = 0.037 Identities = 20/39 (51%), Positives = 25/39 (64%) Frame = +2 Query: 779 DPQXMEDPKLKXIADRLGKTVAQVLIRYQIDXGXIVXPE 895 DP MEDP + IA + G + AQVLIRYQ+ G V P+ Sbjct: 230 DPLLMEDPVVCAIAKKKGVSPAQVLIRYQLQRGVAVLPK 268 >UniRef50_Q96JD6 Cluster: Aldo-keto reductase family 1 member C-like protein 2; n=37; Euteleostomi|Rep: Aldo-keto reductase family 1 member C-like protein 2 - Homo sapiens (Human) Length = 320 Score = 125 bits (302), Expect = 1e-27 Identities = 67/141 (47%), Positives = 83/141 (58%), Gaps = 21/141 (14%) Frame = +1 Query: 388 CRXPWXNLNVQYLDLYLIHWPQAYKEDGSLF-------------------PTDQSGKIQF 510 CR L + YLDLYLIHWP +K + P D+S + Sbjct: 84 CRKSLKALKLNYLDLYLIHWPMGFKPPHPEWIMSCSELSFCLSHPRVQDLPLDESNMVIP 143 Query: 511 SDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQHATV--KPVVNQVECHPYLNQ 684 SD D++DTW+AME LV GLVK+IGVSNFN +QLERLL + KP+ NQ+ECHPYL Q Sbjct: 144 SDTDFLDTWEAMEDLVITGLVKNIGVSNFNHEQLERLLNKPGLRFKPLTNQIECHPYLTQ 203 Query: 685 KRLKEFCEARGVKITXYSPLG 747 K L FC++R V +T Y PLG Sbjct: 204 KNLISFCQSRDVSVTAYRPLG 224 Score = 89.0 bits (211), Expect = 1e-16 Identities = 43/84 (51%), Positives = 48/84 (57%) Frame = +3 Query: 150 PVFGXGXWXSKPGXVXXAVKXAIDIGXRHIDCAYVYGNXXXVGXAITSKIKEGVVTRXXL 329 P G W + PG V AVK AID G RH DCAY Y N VG I KIKEG V R L Sbjct: 5 PAVGLSSWKASPGKVTEAVKEAIDAGYRHFDCAYFYHNEREVGAGIRCKIKEGAVRREDL 64 Query: 330 FITSKLWNTFHRPDLVRGALQEXL 401 FI +KLW T H+ LV A ++ L Sbjct: 65 FIATKLWCTCHKKSLVETACRKSL 88 Score = 35.9 bits (79), Expect = 1.4 Identities = 17/43 (39%), Positives = 25/43 (58%) Frame = +2 Query: 764 GAKPDDPQXMEDPKLKXIADRLGKTVAQVLIRYQIDXGXIVXP 892 G + +++P +K IA GK+ AQ+LIR+QI IV P Sbjct: 224 GGSCEGVDLIDNPVIKRIAKEHGKSPAQILIRFQIQRNVIVIP 266 >UniRef50_Q7QVQ9 Cluster: GLP_302_44328_45269; n=1; Giardia lamblia ATCC 50803|Rep: GLP_302_44328_45269 - Giardia lamblia ATCC 50803 Length = 313 Score = 124 bits (300), Expect = 2e-27 Identities = 57/122 (46%), Positives = 76/122 (62%), Gaps = 2/122 (1%) Frame = +1 Query: 388 CRXPWXNLNVQYLDLYLIHWPQAYKED--GSLFPTDQSGKIQFSDVDYVDTWKAMEPLVK 561 C+ +L V YLDL+L+HWP A+ + G LFP D G+ V DTW+AME LV+ Sbjct: 86 CKKTMSDLQVDYLDLFLVHWPLAFVRNDVGDLFPKDAEGRAMLEKVPLADTWRAMEQLVE 145 Query: 562 EGLVKSIGVSNFNSKQLERLLQHATVKPVVNQVECHPYLNQKRLKEFCEARGVKITXYSP 741 EGLVK IGVSN+ L LL +A +KP+VNQ+E HP+ +FC G+ +T YSP Sbjct: 146 EGLVKHIGVSNYTVPLLADLLNYAKIKPLVNQIEIHPWHPNDATVKFCLDNGIGVTAYSP 205 Query: 742 LG 747 +G Sbjct: 206 MG 207 Score = 74.5 bits (175), Expect = 3e-12 Identities = 37/79 (46%), Positives = 46/79 (58%), Gaps = 2/79 (2%) Frame = +3 Query: 150 PVFGXGXWXSKPGXVXXAVKXAIDIGXRHIDCAYVYGNXXXVGXAITSKIKEGV--VTRX 323 P G G W + P V AV+ A+ G RHIDCAYVY N +G A K+ + R Sbjct: 5 PRLGFGTWQAPPEAVQTAVETALMTGYRHIDCAYVYQNEEAIGRAFGKIFKDASSGIKRE 64 Query: 324 XLFITSKLWNTFHRPDLVR 380 ++ITSKLWN HRP+LVR Sbjct: 65 DVWITSKLWNYNHRPELVR 83 >UniRef50_Q22352 Cluster: Putative uncharacterized protein T08H10.1; n=2; Caenorhabditis|Rep: Putative uncharacterized protein T08H10.1 - Caenorhabditis elegans Length = 333 Score = 124 bits (300), Expect = 2e-27 Identities = 58/126 (46%), Positives = 86/126 (68%), Gaps = 1/126 (0%) Frame = +1 Query: 409 LNVQYLDLYLIHWPQAYK-EDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIG 585 L ++Y+DLYLIH P +K ++GS P ++G++ +++ ++DTW+A+E L KEG +K++G Sbjct: 102 LQLEYIDLYLIHCPFPFKHQEGSFAPLMENGELAVTEIAHIDTWRALEKLYKEGKLKALG 161 Query: 586 VSNFNSKQLERLLQHATVKPVVNQVECHPYLNQKRLKEFCEARGVKITXYSPLGSPDRPW 765 VSNF+ QL+ L A VKP QVECH Y Q+ L+ C+ GV +T Y+PLGSP R Sbjct: 162 VSNFSCNQLQALYDAAEVKPANQQVECHIYWPQQELRALCKKLGVTVTAYAPLGSPGR-- 219 Query: 766 GQARRP 783 +A RP Sbjct: 220 -KAARP 224 Score = 60.5 bits (140), Expect = 6e-08 Identities = 32/89 (35%), Positives = 47/89 (52%), Gaps = 1/89 (1%) Frame = +3 Query: 138 GASXPVFGXGXWXSKP-GXVXXAVKXAIDIGXRHIDCAYVYGNXXXVGXAITSKIKEGVV 314 GA P+FG G W K + A++ A+D G R ID A++Y N +G + I G + Sbjct: 11 GAQLPLFGLGTWQVKDEAELTVALRAALDAGYRLIDTAHLYQNEHIIGKVLHEYISSGKL 70 Query: 315 TRXXLFITSKLWNTFHRPDLVRGALQEXL 401 R +F+TSKL T H P+ V ++ L Sbjct: 71 KREDIFVTSKLPFTAHAPEDVPKCVESQL 99 >UniRef50_Q55FL3 Cluster: Aldo-keto reductase; n=2; Dictyostelium discoideum AX4|Rep: Aldo-keto reductase - Dictyostelium discoideum AX4 Length = 321 Score = 124 bits (299), Expect = 3e-27 Identities = 62/119 (52%), Positives = 80/119 (67%), Gaps = 5/119 (4%) Frame = +1 Query: 406 NLNVQYLDLYLIHWPQAYKEDGSLFPT-----DQSGKIQFSDVDYVDTWKAMEPLVKEGL 570 +L + YLDLYLIHWP A++ L T DQ+G + V +TW+ ME LV+ GL Sbjct: 112 DLGIGYLDLYLIHWPIAFENSNPLGLTIEPLRDQNGNPIIAPVSIRETWQEMEKLVELGL 171 Query: 571 VKSIGVSNFNSKQLERLLQHATVKPVVNQVECHPYLNQKRLKEFCEARGVKITXYSPLG 747 VKSIGVSNFN + L LL +A +KPVVNQVE HPYL Q +L+E+C+ +K+ YSPLG Sbjct: 172 VKSIGVSNFNVQNLVDLLTYAKIKPVVNQVEIHPYLTQFKLQEYCDKYEIKLVAYSPLG 230 Score = 68.5 bits (160), Expect = 2e-10 Identities = 34/81 (41%), Positives = 45/81 (55%), Gaps = 1/81 (1%) Frame = +3 Query: 138 GASXPVFGXGXWXSK-PGXVXXAVKXAIDIGXRHIDCAYVYGNXXXVGXAITSKIKEGVV 314 G P G G + S+ PG V A+ A+ G RHID A YGN +G ++ KEG + Sbjct: 22 GNQIPSIGLGTYYSENPGEVGDAINNALKNGYRHIDGAAFYGNEKVIGNSLKEIFKEGEI 81 Query: 315 TRXXLFITSKLWNTFHRPDLV 377 R +F TSKLWN+ H +LV Sbjct: 82 KREDIFYTSKLWNSCHNSNLV 102 >UniRef50_Q7JVH6 Cluster: LD24696p; n=2; Sophophora|Rep: LD24696p - Drosophila melanogaster (Fruit fly) Length = 311 Score = 123 bits (296), Expect = 7e-27 Identities = 58/128 (45%), Positives = 81/128 (63%), Gaps = 2/128 (1%) Frame = +1 Query: 388 CRXPWXNLNVQYLDLYLIHWPQAYKEDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEG 567 CR NL ++Y+DLYL+H P K ++ G ++ +DVDY+DTW+ ME LV G Sbjct: 96 CRLSLSNLGLEYVDLYLMHMPVGQKFHND---SNVHGTLELTDVDYLDTWREMEKLVDLG 152 Query: 568 LVKSIGVSNFNSKQLERLLQHATVKPVVNQVECHPYLNQKRLKEFCEARGVKITXYSPLG 747 L +SIG+SNFN+ Q ER+L + ++PVVNQVECHP Q++L+E + G+ I Y PL Sbjct: 153 LTRSIGLSNFNAAQTERVLANCRIRPVVNQVECHPGFQQRQLREHAKRHGLVICAYCPLA 212 Query: 748 SPD--RPW 765 P R W Sbjct: 213 RPQPARQW 220 Score = 81.4 bits (192), Expect = 3e-14 Identities = 39/95 (41%), Positives = 50/95 (52%) Frame = +3 Query: 102 MAPXIPVVXFXXGASXPVFGXGXWXSKPGXVXXAVKXAIDIGXRHIDCAYVYGNXXXVGX 281 M P + G P G G W S + + A+D+G RH+D A+VY N VG Sbjct: 1 MTNLAPTIRLNNGREMPTLGLGTWKSFESDAYHSTRHALDVGYRHLDTAFVYENEAEVGQ 60 Query: 282 AITSKIKEGVVTRXXLFITSKLWNTFHRPDLVRGA 386 AI+ KI EGVVTR +F+T+KL H P LV A Sbjct: 61 AISEKIAEGVVTREEVFVTTKLGGIHHDPALVERA 95 >UniRef50_P51857 Cluster: 3-oxo-5-beta-steroid 4-dehydrogenase (EC 1.3.1.3) (Delta(4)-3- ketosteroid 5-beta-reductase); n=124; cellular organisms|Rep: 3-oxo-5-beta-steroid 4-dehydrogenase (EC 1.3.1.3) (Delta(4)-3- ketosteroid 5-beta-reductase) - Homo sapiens (Human) Length = 326 Score = 123 bits (296), Expect = 7e-27 Identities = 59/129 (45%), Positives = 79/129 (61%), Gaps = 3/129 (2%) Frame = +1 Query: 409 LNVQYLDLYLIHWPQAYKEDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGV 588 L + Y+DLY+I P A+K ++P D++GK + + TW+AME GLVKS+GV Sbjct: 109 LQLDYVDLYIIEVPMAFKPGDEIYPRDENGKWLYHKSNLCATWEAMEACKDAGLVKSLGV 168 Query: 589 SNFNSKQLERLLQHATV--KPVVNQVECHPYLNQKRLKEFCEARGVKITXYSPLGSPDRP 762 SNFN +QLE +L + KPV NQVECHPY Q +L +FC+ + IT YSPLG+ P Sbjct: 169 SNFNRRQLELILNKPGLKHKPVSNQVECHPYFTQPKLLKFCQQHDIVITAYSPLGTSRNP 228 Query: 763 -WGQARRPP 786 W PP Sbjct: 229 IWVNVSSPP 237 Score = 76.6 bits (180), Expect = 8e-13 Identities = 43/92 (46%), Positives = 51/92 (55%), Gaps = 4/92 (4%) Frame = +3 Query: 138 GASXPVFGXGXWX---SKP-GXVXXAVKXAIDIGXRHIDCAYVYGNXXXVGXAITSKIKE 305 G S P+ G G + S P G +VK AID G RHID AY+Y N VG AI KI E Sbjct: 15 GNSIPIIGLGTYSEPKSTPKGACATSVKVAIDTGYRHIDGAYIYQNEHEVGEAIREKIAE 74 Query: 306 GVVTRXXLFITSKLWNTFHRPDLVRGALQEXL 401 G V R +F KLW T H P++VR L+ L Sbjct: 75 GKVRREDIFYCGKLWATNHVPEMVRPTLERTL 106 >UniRef50_Q0PGJ6 Cluster: Aldo-keto reductase; n=32; Magnoliophyta|Rep: Aldo-keto reductase - Arabidopsis thaliana (Mouse-ear cress) Length = 315 Score = 121 bits (291), Expect = 3e-26 Identities = 59/120 (49%), Positives = 80/120 (66%) Frame = +1 Query: 406 NLNVQYLDLYLIHWPQAYKEDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIG 585 +L ++Y+DLYLIHWP K+ GS+ ++ VD TWKAME L G ++IG Sbjct: 102 DLQLEYVDLYLIHWPARIKK-GSVGIKPEN----LLPVDIPSTWKAMEALYDSGKARAIG 156 Query: 586 VSNFNSKQLERLLQHATVKPVVNQVECHPYLNQKRLKEFCEARGVKITXYSPLGSPDRPW 765 VSNF++K+L LL+ A V P VNQVECHP Q +L+EFC+++GV ++ YSPLGSP W Sbjct: 157 VSNFSTKKLADLLELARVPPAVNQVECHPSWRQTKLQEFCKSKGVHLSAYSPLGSPGTTW 216 Score = 87.4 bits (207), Expect = 4e-16 Identities = 45/100 (45%), Positives = 52/100 (52%) Frame = +3 Query: 102 MAPXIPVVXFXXGASXPVFGXGXWXSKPGXVXXAVKXAIDIGXRHIDCAYVYGNXXXVGX 281 MA I GA P G G W + PG V AV A+ IG RHIDCA +YGN +G Sbjct: 1 MANAITFFKLNTGAKFPSVGLGTWQASPGLVGDAVAAAVKIGYRHIDCAQIYGNEKEIGA 60 Query: 282 AITSKIKEGVVTRXXLFITSKLWNTFHRPDLVRGALQEXL 401 + ++ VV R LFITSKLW T H P V AL L Sbjct: 61 VLKKLFEDRVVKREDLFITSKLWCTDHDPQDVPEALNRTL 100 >UniRef50_Q8K023 Cluster: Aldo-keto reductase family 1 member C18; n=72; Tetrapoda|Rep: Aldo-keto reductase family 1 member C18 - Mus musculus (Mouse) Length = 323 Score = 120 bits (290), Expect = 4e-26 Identities = 57/116 (49%), Positives = 73/116 (62%), Gaps = 2/116 (1%) Frame = +1 Query: 409 LNVQYLDLYLIHWPQAYKEDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGV 588 LN+ Y+DLYLIH+P + K L P D+ G + F VD DTW+AME GL KSIGV Sbjct: 106 LNLDYVDLYLIHFPVSLKPGNELLPKDEHGNLIFDTVDLCDTWEAMEKCKDAGLAKSIGV 165 Query: 589 SNFNSKQLERLLQHATV--KPVVNQVECHPYLNQKRLKEFCEARGVKITXYSPLGS 750 SNFN +QLE +L + KPV NQVECH YLNQ +L +C+ + + Y LG+ Sbjct: 166 SNFNRRQLEMILNKPGLKYKPVCNQVECHLYLNQSKLLAYCKMNDIVLVAYGALGT 221 Score = 84.6 bits (200), Expect = 3e-15 Identities = 43/103 (41%), Positives = 61/103 (59%), Gaps = 3/103 (2%) Frame = +3 Query: 102 MAPXIPVVXFXXGASXPVFGXGXWXSKPGXVXXAV---KXAIDIGXRHIDCAYVYGNXXX 272 M I + G S PV G G + ++ ++ K AID+G HIDC+++Y N Sbjct: 1 MNSKIQKIELNDGHSIPVLGFGTYATEEHLKKKSMESTKIAIDVGFCHIDCSHLYQNEEE 60 Query: 273 VGXAITSKIKEGVVTRXXLFITSKLWNTFHRPDLVRGALQEXL 401 +G AI SKI++G V R +F TSKLW+T HRP+LVR +L+ L Sbjct: 61 IGQAILSKIEDGTVKREDIFYTSKLWSTSHRPELVRPSLENSL 103 >UniRef50_Q8VC28 Cluster: Aldo-keto reductase family 1 member C13; n=11; Theria|Rep: Aldo-keto reductase family 1 member C13 - Mus musculus (Mouse) Length = 323 Score = 120 bits (289), Expect = 5e-26 Identities = 54/116 (46%), Positives = 77/116 (66%), Gaps = 2/116 (1%) Frame = +1 Query: 409 LNVQYLDLYLIHWPQAYKEDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGV 588 L + Y+DLY++H+P K + FP ++ GK VD+ DTW+ +E GLVKSIGV Sbjct: 106 LQLDYVDLYIMHYPVPMKSGDNDFPVNEQGKSLLDTVDFCDTWERLEECKDAGLVKSIGV 165 Query: 589 SNFNSKQLERLLQHATV--KPVVNQVECHPYLNQKRLKEFCEARGVKITXYSPLGS 750 SNFN +QLER+L + KPV NQVECH YLNQ++L ++CE++ + + Y LG+ Sbjct: 166 SNFNHRQLERILNKPGLKYKPVCNQVECHLYLNQRKLLDYCESKDIVLVAYGALGT 221 Score = 75.4 bits (177), Expect = 2e-12 Identities = 42/96 (43%), Positives = 52/96 (54%), Gaps = 3/96 (3%) Frame = +3 Query: 123 VXFXXGASXPVFGXGXWXSKP---GXVXXAVKXAIDIGXRHIDCAYVYGNXXXVGXAITS 293 V G P G G + K A A+D+G RH+D AY Y +G AI S Sbjct: 8 VKLNDGHLIPALGFGTYKPKEVPKSKSLEAACLALDVGYRHVDTAYAYQVEEEIGQAIQS 67 Query: 294 KIKEGVVTRXXLFITSKLWNTFHRPDLVRGALQEXL 401 KIK GVV R LFIT+KLW T RP+LV+ AL++ L Sbjct: 68 KIKAGVVKREDLFITTKLWCTCFRPELVKPALEKSL 103 >UniRef50_Q54B70 Cluster: Aldehyde reductase; n=2; Dictyostelium discoideum|Rep: Aldehyde reductase - Dictyostelium discoideum AX4 Length = 297 Score = 118 bits (285), Expect = 2e-25 Identities = 57/115 (49%), Positives = 77/115 (66%) Frame = +1 Query: 406 NLNVQYLDLYLIHWPQAYKEDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIG 585 +L +QYLDLYL+HWP A++ + T SG Q V +TW+ ME LV GLVKSIG Sbjct: 100 DLGLQYLDLYLVHWPVAFEYTSNDIQT--SGSTQ-EFVSIRETWEEMEKLVDAGLVKSIG 156 Query: 586 VSNFNSKQLERLLQHATVKPVVNQVECHPYLNQKRLKEFCEARGVKITXYSPLGS 750 +SNFN + L +L +A +KP NQVE HP+L+Q LK+FC+ + +T YSPLG+ Sbjct: 157 LSNFNVQGLMEVLSYARIKPAANQVELHPFLSQPELKKFCDKHNIHLTAYSPLGN 211 Score = 87.0 bits (206), Expect = 6e-16 Identities = 45/96 (46%), Positives = 54/96 (56%), Gaps = 1/96 (1%) Frame = +3 Query: 117 PVVXFXXGASXPVFGXGXWXSKPGXVXXAVKXAIDIGXRHIDCAYVYGNXXXVGXAITSK 296 P G P+ G G W ++ V AV+ A+D G RHIDCA VY N VG A T K Sbjct: 3 PSFKLSSGHKIPLVGFGTWKAETTLVGKAVEVALDAGYRHIDCAAVYLNEKEVGEAFTKK 62 Query: 297 I-KEGVVTRXXLFITSKLWNTFHRPDLVRGALQEXL 401 E V R +FITSKLWNTFH+ + VR AL+ L Sbjct: 63 FTTEATVKREDVFITSKLWNTFHKKEHVRPALERTL 98 >UniRef50_A2EYY6 Cluster: Oxidoreductase, aldo/keto reductase family protein; n=9; Trichomonas vaginalis G3|Rep: Oxidoreductase, aldo/keto reductase family protein - Trichomonas vaginalis G3 Length = 308 Score = 118 bits (285), Expect = 2e-25 Identities = 64/137 (46%), Positives = 83/137 (60%), Gaps = 5/137 (3%) Frame = +1 Query: 388 CRXPWXNLNVQYLDLYLIHWPQAYKEDG---SLFPTDQSGKIQFSD-VDYVDTWKAMEPL 555 CR +L + YLDLYL+H+P A++ G SL P D+ G F D V +DTWKAME L Sbjct: 85 CRKTLKDLRLDYLDLYLMHYPFAFQNTGIGGSLNPLDEKGNTIFDDGVSLIDTWKAMEKL 144 Query: 556 VKEGLVKSIGVSNFNSKQLERL-LQHATVKPVVNQVECHPYLNQKRLKEFCEARGVKITX 732 V++GLVK IGVSN+ QLERL A P NQVE + Y+ Q L+E+ G+ +T Sbjct: 145 VEKGLVKRIGVSNWTINQLERLKYSDAKTTPYTNQVEFNLYMQQGPLREYMHKEGIIVTG 204 Query: 733 YSPLGSPDRPWGQARRP 783 YS LG+PD W + P Sbjct: 205 YSTLGTPD--WAKPDEP 219 Score = 58.8 bits (136), Expect = 2e-07 Identities = 34/86 (39%), Positives = 46/86 (53%), Gaps = 2/86 (2%) Frame = +3 Query: 150 PVFGXGXWXS-KPGXVXXAVKXAI-DIGXRHIDCAYVYGNXXXVGXAITSKIKEGVVTRX 323 P G G W S + + A+ AI + G HIDCA Y N VG A+ G+ R Sbjct: 5 PTIGLGTWKSPRSEDLVNAITYAIKEAGYVHIDCALCYENEDIVGQALQQCWDSGI-KRE 63 Query: 324 XLFITSKLWNTFHRPDLVRGALQEXL 401 ++ITSKLWNT HR ++V A ++ L Sbjct: 64 NIWITSKLWNTHHRLEIVEEACRKTL 89 Score = 33.1 bits (72), Expect = 9.9 Identities = 14/36 (38%), Positives = 23/36 (63%) Frame = +2 Query: 755 TDPGAKPDDPQXMEDPKLKXIADRLGKTVAQVLIRY 862 T AKPD+P ++D +L IA GK+V +V +++ Sbjct: 210 TPDWAKPDEPVVLKDEELNKIAAETGKSVGEVELKF 245 >UniRef50_A2R6Z3 Cluster: Catalytic activity: an alcohol + NADP(+) <=> an aldehyde + NADPH; n=9; Pezizomycotina|Rep: Catalytic activity: an alcohol + NADP(+) <=> an aldehyde + NADPH - Aspergillus niger Length = 345 Score = 118 bits (285), Expect = 2e-25 Identities = 55/117 (47%), Positives = 77/117 (65%), Gaps = 2/117 (1%) Frame = +1 Query: 406 NLNVQYLDLYLIHWPQAYKEDGSLFP--TDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKS 579 +L YLDLYLIHWP A++ + +Q+G I DV DTW AME LV++G V+S Sbjct: 97 DLQTDYLDLYLIHWPVAFRYSTTTIQPVNEQTGLIDVVDVPIKDTWAAMEKLVEKGKVRS 156 Query: 580 IGVSNFNSKQLERLLQHATVKPVVNQVECHPYLNQKRLKEFCEARGVKITXYSPLGS 750 IGVSNF +++E LL+ A + P VNQ+E HP+L Q+ L E+ +G+ + YSPLG+ Sbjct: 157 IGVSNFTREKIEELLKTAKITPAVNQIEAHPFLQQRDLLEWSTQKGIVVAGYSPLGN 213 Score = 70.5 bits (165), Expect = 5e-11 Identities = 39/96 (40%), Positives = 48/96 (50%) Frame = +3 Query: 138 GASXPVFGXGXWXSKPGXVXXAVKXAIDIGXRHIDCAYVYGNXXXVGXAITSKIKEGVVT 317 G P G G W SK V AV A+ G RHID A VYGN VG ++ V Sbjct: 12 GYDMPAVGLGTWQSKKDEVRDAVIAALKCGYRHIDAAAVYGNEQEVGDG----MRLSGVP 67 Query: 318 RXXLFITSKLWNTFHRPDLVRGALQEXLXQSERSVL 425 R +F+TSKLWNT H P+ V A+ + L + L Sbjct: 68 REEIFLTSKLWNTHHHPENVEEAVDKSLADLQTDYL 103 Score = 34.7 bits (76), Expect = 3.3 Identities = 15/38 (39%), Positives = 24/38 (63%) Frame = +2 Query: 782 PQXMEDPKLKXIADRLGKTVAQVLIRYQIDXGXIVXPE 895 P+ ++DP + A +L KT AQVLI + + G +V P+ Sbjct: 219 PRAVDDPLVIETAKKLNKTPAQVLISWAVQRGTVVLPK 256 >UniRef50_UPI0000D9A956 Cluster: PREDICTED: similar to aldo-keto reductase family 1, member B10, partial; n=1; Macaca mulatta|Rep: PREDICTED: similar to aldo-keto reductase family 1, member B10, partial - Macaca mulatta Length = 275 Score = 118 bits (283), Expect = 3e-25 Identities = 61/128 (47%), Positives = 79/128 (61%), Gaps = 2/128 (1%) Frame = +1 Query: 406 NLNVQYLDLYLIHWPQAYKEDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIG 585 +L + YLD+YLIHWPQ +K AME LV EGLVK++G Sbjct: 125 DLKLSYLDVYLIHWPQGFK--------------------------AMEELVDEGLVKALG 158 Query: 586 VSNFNSKQLERLLQHATV--KPVVNQVECHPYLNQKRLKEFCEARGVKITXYSPLGSPDR 759 +SNFN Q+E+LL + KPV NQVECHPYL Q++L ++C ++G+ IT YSPLGSPDR Sbjct: 159 ISNFNHFQIEKLLNKPGLKYKPVTNQVECHPYLTQEKLIQYCHSKGITITAYSPLGSPDR 218 Query: 760 PWGQARRP 783 PW + P Sbjct: 219 PWAKPEDP 226 Score = 74.5 bits (175), Expect = 3e-12 Identities = 44/86 (51%), Positives = 48/86 (55%), Gaps = 6/86 (6%) Frame = +3 Query: 186 GXVXXAVKXAIDIGXRHIDCAYVYGNXXXVGXAITSKIKEGVVTRXXLFITSK------L 347 G V AVK AID G RHIDCAYVY N VG AI KI+E V R LFI SK L Sbjct: 46 GKVKEAVKVAIDAGYRHIDCAYVYQNEHEVGEAIQEKIQEQAVKREDLFIVSKVHMAHWL 105 Query: 348 WNTFHRPDLVRGALQEXLXQSERSVL 425 W TF LVR A ++ L + S L Sbjct: 106 WTTFFERPLVRKAFEKTLKDLKLSYL 131 Score = 52.8 bits (121), Expect = 1e-05 Identities = 24/45 (53%), Positives = 31/45 (68%) Frame = +2 Query: 761 PGAKPDDPQXMEDPKLKXIADRLGKTVAQVLIRYQIDXGXIVXPE 895 P AKP+DP +E+PK+K IA + KT AQVLIR+ I IV P+ Sbjct: 219 PWAKPEDPSLLEEPKIKEIAAKHKKTTAQVLIRFHIQRNVIVIPK 263 >UniRef50_UPI000065D0BD Cluster: Homolog of Homo sapiens "AKR1B1 protein.; n=1; Takifugu rubripes|Rep: Homolog of Homo sapiens "AKR1B1 protein. - Takifugu rubripes Length = 330 Score = 116 bits (280), Expect = 6e-25 Identities = 61/165 (36%), Positives = 90/165 (54%), Gaps = 26/165 (15%) Frame = +1 Query: 388 CRXPWXNLNVQYLDLYLIHWPQA------------------YKEDGSL------FPTDQS 495 C +LN+ Y+DLYL+H+P +++ L FP D+ Sbjct: 93 CEKTLSSLNLDYVDLYLMHFPMGALSATLDLTSLTDVIPTVFRDFSPLQPGEDPFPLDEH 152 Query: 496 GKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQHATVK--PVVNQVECH 669 ++ ++DTW+AME LV +GL K+IG+SNFN Q+E +L +K P NQ+ECH Sbjct: 153 NQLICDGTSFLDTWEAMEELVDDGLAKAIGISNFNKDQIEAVLNKPGLKHKPATNQIECH 212 Query: 670 PYLNQKRLKEFCEARGVKITXYSPLGSPDRPWGQARRPPXHGGPQ 804 P+LNQ++L FC +RG+ +T ++ LGS DR W A P PQ Sbjct: 213 PHLNQEKLIHFCRSRGISVTAFACLGSADRSWASADEPSFLDDPQ 257 Score = 100 bits (240), Expect = 4e-20 Identities = 51/96 (53%), Positives = 56/96 (58%) Frame = +3 Query: 114 IPVVXFXXGASXPVFGXGXWXSKPGXVXXAVKXAIDIGXRHIDCAYVYGNXXXVGXAITS 293 IP V GA PV G G W S G AVK AI G RHID AYVY N VG + + Sbjct: 2 IPSVTLNTGALMPVLGLGTWKSGKGVTTEAVKVAIGAGYRHIDTAYVYENETEVGAGVQA 61 Query: 294 KIKEGVVTRXXLFITSKLWNTFHRPDLVRGALQEXL 401 I +GVV R LFI SKLW TFH P LVRGA ++ L Sbjct: 62 MIDQGVVKREELFIVSKLWCTFHTPSLVRGACEKTL 97 Score = 34.7 bits (76), Expect = 3.3 Identities = 15/34 (44%), Positives = 23/34 (67%) Frame = +2 Query: 767 AKPDDPQXMEDPKLKXIADRLGKTVAQVLIRYQI 868 A D+P ++DP++ IA + T AQVLI++QI Sbjct: 245 ASADEPSFLDDPQINAIARKNQMTPAQVLIKFQI 278 >UniRef50_Q2S340 Cluster: Aldehyde reductase; n=10; Bacteria|Rep: Aldehyde reductase - Salinibacter ruber (strain DSM 13855) Length = 321 Score = 116 bits (278), Expect = 1e-24 Identities = 58/119 (48%), Positives = 72/119 (60%) Frame = +1 Query: 406 NLNVQYLDLYLIHWPQAYKEDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIG 585 +L + LDLYLIHWP A + + FP + V +TW AME L K+GLV+ IG Sbjct: 98 DLRLDALDLYLIHWPVALQPEVD-FPESPDDFVSPEAVPLTETWAAMEALKKDGLVRHIG 156 Query: 586 VSNFNSKQLERLLQHATVKPVVNQVECHPYLNQKRLKEFCEARGVKITXYSPLGSPDRP 762 VSNF+ L+ +L V+P +NQVE HPYL Q L F EA + IT YSPLGS DRP Sbjct: 157 VSNFSVPNLQMILDAGEVRPEMNQVEMHPYLPQPELVSFAEAHNIPITAYSPLGSGDRP 215 Score = 90.2 bits (214), Expect = 6e-17 Identities = 40/93 (43%), Positives = 54/93 (58%) Frame = +3 Query: 123 VXFXXGASXPVFGXGXWXSKPGXVXXAVKXAIDIGXRHIDCAYVYGNXXXVGXAITSKIK 302 + F G P+ G G W S PG V AV A++ G RH+DCA +Y N VG A++ Sbjct: 4 ISFENGDEMPMIGLGTWKSPPGEVYEAVTTALEAGYRHVDCAPIYKNETEVGAALSDSFD 63 Query: 303 EGVVTRXXLFITSKLWNTFHRPDLVRGALQEXL 401 G + R +++TSKLWN H PD VR AL++ L Sbjct: 64 AGGIRRDDVWVTSKLWNNAHHPDDVRPALEQTL 96 Score = 38.7 bits (86), Expect = 0.20 Identities = 20/53 (37%), Positives = 29/53 (54%) Frame = +2 Query: 737 LPSARRTDPGAKPDDPQXMEDPKLKXIADRLGKTVAQVLIRYQIDXGXIVXPE 895 L S R D D+P M +P + IADR G + AQVL+++ + G V P+ Sbjct: 209 LGSGDRPDAMKADDEPTLMANPTINDIADRHGVSPAQVLLQWGVARGTAVIPK 261 >UniRef50_Q01J82 Cluster: OSIGBa0152K17.5 protein; n=28; Magnoliophyta|Rep: OSIGBa0152K17.5 protein - Oryza sativa (Rice) Length = 323 Score = 115 bits (277), Expect = 1e-24 Identities = 50/114 (43%), Positives = 75/114 (65%) Frame = +1 Query: 406 NLNVQYLDLYLIHWPQAYKEDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIG 585 NL ++Y+DLYL+HWP + K + P + + F D+ W+AME + GL K+IG Sbjct: 107 NLQMEYVDLYLVHWPISVKPGPPMLPVKREDAVPF---DFEGVWRAMEECHRLGLAKAIG 163 Query: 586 VSNFNSKQLERLLQHATVKPVVNQVECHPYLNQKRLKEFCEARGVKITXYSPLG 747 VSNF +K L++LL AT+ P VNQVE +P Q+ ++E+C A+G+++ YSPLG Sbjct: 164 VSNFTTKHLDKLLAVATIPPAVNQVEMNPVWQQRTVREYCAAKGIRVAAYSPLG 217 Score = 56.0 bits (129), Expect = 1e-06 Identities = 36/102 (35%), Positives = 51/102 (50%), Gaps = 6/102 (5%) Frame = +3 Query: 114 IPVVXFXXGASXPV--FGXGXWXS---KPGXVXXAVKXAIDIGXRHIDCAYVYGNXXXVG 278 +P V GA P+ G G S P A A+++G RH D A +YG +G Sbjct: 4 VPEVALRHGAGRPMPAVGVGTADSAATSPETKRGAALAALEVGFRHFDTAALYGTEAPLG 63 Query: 279 XAITSKIKEGVV-TRXXLFITSKLWNTFHRPDLVRGALQEXL 401 AI + G+V +R +F+T+KLW T P LV +L+E L Sbjct: 64 EAIAEATRRGLVASREEVFVTTKLWCTQCHPGLVLPSLRESL 105 >UniRef50_UPI0000499B0E Cluster: oxidoreductase, aldo/keto reductase family; n=1; Entamoeba histolytica HM-1:IMSS|Rep: oxidoreductase, aldo/keto reductase family - Entamoeba histolytica HM-1:IMSS Length = 307 Score = 114 bits (275), Expect = 3e-24 Identities = 54/120 (45%), Positives = 76/120 (63%) Frame = +1 Query: 388 CRXPWXNLNVQYLDLYLIHWPQAYKEDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEG 567 C +L +YLDLYLIHWP A K D S P + F D+D + W+ ME LV EG Sbjct: 91 CLESIQDLKCKYLDLYLIHWPIALKVDASNPPKPED----FLDMDITEIWQEMERLVDEG 146 Query: 568 LVKSIGVSNFNSKQLERLLQHATVKPVVNQVECHPYLNQKRLKEFCEARGVKITXYSPLG 747 LVKSIG+SNF Q+E++++ +KPV+NQVE + YL Q +L+E C++ + + Y P+G Sbjct: 147 LVKSIGLSNFTIPQIEKIMKMCRIKPVINQVELNVYLQQNKLREVCKSYNIVVEAYRPIG 206 Score = 52.8 bits (121), Expect = 1e-05 Identities = 30/72 (41%), Positives = 36/72 (50%), Gaps = 1/72 (1%) Frame = +3 Query: 138 GASXPVFGXGXWXSKPGXVXXAVKXAIDIGXRHIDCAYVYGNXXXVG-XAITSKIKEGVV 314 G P G G W + PG V AV A++ G R IDCA Y N +G I +K Sbjct: 11 GKFMPAIGLGTWLAAPGEVGKAVTLALENGYRLIDCARFYKNEKEIGEMGIEPFLKNH-- 68 Query: 315 TRXXLFITSKLW 350 R LF+TSKLW Sbjct: 69 PREELFVTSKLW 80 >UniRef50_UPI00015B4B22 Cluster: PREDICTED: similar to GA15457-PA; n=1; Nasonia vitripennis|Rep: PREDICTED: similar to GA15457-PA - Nasonia vitripennis Length = 388 Score = 114 bits (274), Expect = 3e-24 Identities = 56/116 (48%), Positives = 75/116 (64%), Gaps = 1/116 (0%) Frame = +1 Query: 406 NLNVQYLDLYLIHWPQAYKEDGSLFPT-DQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSI 582 +L + Y+D+YLIH P A KE +L D+ G F DVD+ WKAME VKEG KSI Sbjct: 119 DLGLDYVDMYLIHTPFAVKEGENLSSKQDKDGNDLFDDVDHKALWKAMERQVKEGRAKSI 178 Query: 583 GVSNFNSKQLERLLQHATVKPVVNQVECHPYLNQKRLKEFCEARGVKITXYSPLGS 750 G+SNFN Q+ + +A +KP QVE H YL QK+L++FC+ + +T Y+PLGS Sbjct: 179 GLSNFNQSQVLNIYNNAEIKPSNLQVETHAYLQQKQLRKFCKEHNIVMTAYAPLGS 234 Score = 46.4 bits (105), Expect = 0.001 Identities = 29/88 (32%), Positives = 41/88 (46%) Frame = +3 Query: 138 GASXPVFGXGXWXSKPGXVXXAVKXAIDIGXRHIDCAYVYGNXXXVGXAITSKIKEGVVT 317 G P G G K + A+ A++ G RHID A+ Y N +G + +G Sbjct: 31 GHEIPAVGLGTSTIKLDEMDNAISSALENGYRHIDTAFSYDNEAAIGKILKKWFDKG-GK 89 Query: 318 RXXLFITSKLWNTFHRPDLVRGALQEXL 401 R +FITSKL + +RP V L+ L Sbjct: 90 REDIFITSKLPSQGNRPQSVETYLKRSL 117 >UniRef50_Q7ZA52 Cluster: Aldose reductase; n=6; Pezizomycotina|Rep: Aldose reductase - Magnaporthe grisea (Rice blast fungus) (Pyricularia grisea) Length = 312 Score = 114 bits (274), Expect = 3e-24 Identities = 56/121 (46%), Positives = 73/121 (60%), Gaps = 3/121 (2%) Frame = +1 Query: 409 LNVQYLDLYLIHWPQAYKEDGS--LFPTDQSGKIQFSDV-DYVDTWKAMEPLVKEGLVKS 579 L + Y+DLYL+HWP +G+ FP G ++VDTWK ME L G K+ Sbjct: 99 LGLDYVDLYLVHWPILMNPEGNDEKFPKHADGSRDIIHTHNHVDTWKLMEKLPATGKTKA 158 Query: 580 IGVSNFNSKQLERLLQHATVKPVVNQVECHPYLNQKRLKEFCEARGVKITXYSPLGSPDR 759 +GVSN++ LE+LL HAT P VNQVE HP L Q+ L +FC+ +G+ I YSPLGS Sbjct: 159 VGVSNYSKAWLEQLLPHATTVPAVNQVENHPQLPQQELVDFCKEKGIHIMAYSPLGSTGG 218 Query: 760 P 762 P Sbjct: 219 P 219 Score = 72.1 bits (169), Expect = 2e-11 Identities = 35/74 (47%), Positives = 39/74 (52%) Frame = +3 Query: 138 GASXPVFGXGXWXSKPGXVXXAVKXAIDIGXRHIDCAYVYGNXXXVGXAITSKIKEGVVT 317 GA P FG G W G + AV AI G R ID AYVYGN VG I I G+V Sbjct: 11 GAKIPAFGLGTWQGDKGVIKEAVLTAIKSGYRLIDGAYVYGNEEEVGQGIREAISSGIVK 70 Query: 318 RXXLFITSKLWNTF 359 R LF+ SK W T+ Sbjct: 71 REDLFVVSKCWATY 84 >UniRef50_Q10494 Cluster: Probable oxidoreductase C26F1.07; n=2; Schizosaccharomyces pombe|Rep: Probable oxidoreductase C26F1.07 - Schizosaccharomyces pombe (Fission yeast) Length = 321 Score = 114 bits (274), Expect = 3e-24 Identities = 52/115 (45%), Positives = 73/115 (63%) Frame = +1 Query: 406 NLNVQYLDLYLIHWPQAYKEDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIG 585 +L + YLD YLIHWP ++K FP D+ G + + +TWKAME L++ G V+ IG Sbjct: 106 DLKLDYLDEYLIHWPVSFKTGEDKFPKDKDGNLIYEKNPIEETWKAMEKLLETGKVRHIG 165 Query: 586 VSNFNSKQLERLLQHATVKPVVNQVECHPYLNQKRLKEFCEARGVKITXYSPLGS 750 +SNFN LER+L+ A VKP V+Q+E HP+L Q E + G+ +T YSP G+ Sbjct: 166 LSNFNDTNLERILKVAKVKPAVHQMELHPFLPQTEFVEKHKKLGIHVTAYSPFGN 220 Score = 73.7 bits (173), Expect = 6e-12 Identities = 38/88 (43%), Positives = 48/88 (54%) Frame = +3 Query: 138 GASXPVFGXGXWXSKPGXVXXAVKXAIDIGXRHIDCAYVYGNXXXVGXAITSKIKEGVVT 317 G+ P G G W S+P AVK A+ G RHID A +YGN VG IKE V Sbjct: 21 GSKIPGLGLGTWRSEPNQTKNAVKTALQYGYRHIDAAAIYGNEDEVGDG----IKESGVP 76 Query: 318 RXXLFITSKLWNTFHRPDLVRGALQEXL 401 R +++TSKLW H P+ V AL++ L Sbjct: 77 RKDIWVTSKLWCNAHAPEAVPKALEKTL 104 >UniRef50_UPI00015B4912 Cluster: PREDICTED: similar to aldo-keto reductase; n=1; Nasonia vitripennis|Rep: PREDICTED: similar to aldo-keto reductase - Nasonia vitripennis Length = 353 Score = 113 bits (272), Expect = 6e-24 Identities = 57/118 (48%), Positives = 74/118 (62%), Gaps = 3/118 (2%) Frame = +1 Query: 409 LNVQYLDLYLIHWPQA--YKEDGSLFPTDQSGKIQF-SDVDYVDTWKAMEPLVKEGLVKS 579 L +QYLD+YLIH P A +KED T++ G + + D + WK ME VKEG KS Sbjct: 125 LGLQYLDMYLIHAPFAVHHKEDSYELATNEDGSVVLDTQTDPIAVWKEMEKQVKEGRTKS 184 Query: 580 IGVSNFNSKQLERLLQHATVKPVVNQVECHPYLNQKRLKEFCEARGVKITXYSPLGSP 753 IG+SNFN Q+ +L+ A +KP QVE H Y QK L EFC+ G+ +T Y+PLGSP Sbjct: 185 IGLSNFNETQITNILKEAKIKPSNLQVEVHAYHQQKPLIEFCQKNGIIVTGYAPLGSP 242 Score = 37.9 bits (84), Expect = 0.35 Identities = 22/80 (27%), Positives = 37/80 (46%) Frame = +3 Query: 138 GASXPVFGXGXWXSKPGXVXXAVKXAIDIGXRHIDCAYVYGNXXXVGXAITSKIKEGVVT 317 G + P+ G G + + A++ G HID ++VY N +G + +G Sbjct: 36 GHNFPIVGLGTHGLNEDVLETVLTGALEKGIGHIDTSFVYKNEETIGKVLKDWFAKG-GK 94 Query: 318 RXXLFITSKLWNTFHRPDLV 377 R +F+TSKL + P+ V Sbjct: 95 REDIFVTSKLPYYDNHPESV 114 >UniRef50_A3C1Z7 Cluster: Putative uncharacterized protein; n=2; Oryza sativa (japonica cultivar-group)|Rep: Putative uncharacterized protein - Oryza sativa subsp. japonica (Rice) Length = 288 Score = 113 bits (271), Expect = 8e-24 Identities = 53/121 (43%), Positives = 74/121 (61%), Gaps = 2/121 (1%) Frame = +1 Query: 409 LNVQYLDLYLIHWPQAYK--EDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSI 582 + ++YLDLYLIH+P + + ED + + +D WK ME + GL K+I Sbjct: 105 MQMEYLDLYLIHFPVSMRLAEDPESMTYSKDDLVM---MDMEGVWKEMEECQRLGLTKAI 161 Query: 583 GVSNFNSKQLERLLQHATVKPVVNQVECHPYLNQKRLKEFCEARGVKITXYSPLGSPDRP 762 GVSNF+ K+LE LL AT+ P NQVE HPY Q +L+EFC+ +G+++ YSPLG P Sbjct: 162 GVSNFSCKKLETLLSFATISPAANQVEVHPYCRQNKLREFCKEKGIQLCAYSPLGGKGTP 221 Query: 763 W 765 W Sbjct: 222 W 222 Score = 51.6 bits (118), Expect = 3e-05 Identities = 29/82 (35%), Positives = 41/82 (50%), Gaps = 1/82 (1%) Frame = +3 Query: 183 PGXVXXAVKXAIDIGXRHIDCAYVYGNXXXVGXAITSKIKEGVV-TRXXLFITSKLWNTF 359 P V V AI+ G RH D A VY +G A+ ++ G+V +R L+ITSKLW Sbjct: 29 PSTVKDVVLRAIEAGYRHFDTAAVYQTEAILGDAVAEAVRAGLVASRDELYITSKLWVAH 88 Query: 360 HRPDLVRGALQEXLXQSERSVL 425 P V +L+ L + + L Sbjct: 89 AHPGHVLPSLRRALRKMQMEYL 110 >UniRef50_Q16K66 Cluster: Aldo-keto reductase; n=2; Aedes aegypti|Rep: Aldo-keto reductase - Aedes aegypti (Yellowfever mosquito) Length = 303 Score = 113 bits (271), Expect = 8e-24 Identities = 54/123 (43%), Positives = 79/123 (64%), Gaps = 1/123 (0%) Frame = +1 Query: 388 CRXPWXNLNVQYLDLYLIHWPQAYKEDGSLFPTDQSGKIQFSD-VDYVDTWKAMEPLVKE 564 CR L + Y+DLYL+H P A ++ G D + + + D V ++TWKA+E ++ Sbjct: 91 CRLSLERLGLDYVDLYLMHTPVAARDSG-----DGNDRSEIDDEVTPLETWKALEECQRK 145 Query: 565 GLVKSIGVSNFNSKQLERLLQHATVKPVVNQVECHPYLNQKRLKEFCEARGVKITXYSPL 744 GLV+SIGVSNFN +QL ++ H +++PVVNQVEC +Q +L++FC G+ I YSPL Sbjct: 146 GLVRSIGVSNFNEEQLMEIVTHGSIRPVVNQVECSIGFHQVKLRKFCNREGILIMAYSPL 205 Query: 745 GSP 753 G P Sbjct: 206 GKP 208 Score = 58.8 bits (136), Expect = 2e-07 Identities = 32/81 (39%), Positives = 42/81 (51%), Gaps = 1/81 (1%) Frame = +3 Query: 138 GASXPVFGXGXWXSKPGXVXXAVKXAIDIGXRHIDCAYVYGNXXXVGXAITSKIKEG-VV 314 G S P G G + A+K A++ G R ID A+VY N VG A+ +G + Sbjct: 7 GHSIPPIGLGTYKITGSDGVAAIKSAVEFGYRLIDTAFVYNNEQVVGQALREIFSQGNDI 66 Query: 315 TRXXLFITSKLWNTFHRPDLV 377 R +FI SKL TFHRP+ V Sbjct: 67 NREDVFIVSKLGPTFHRPEAV 87 >UniRef50_Q0IBY6 Cluster: Alcohol dehydrogenase; n=2; Chroococcales|Rep: Alcohol dehydrogenase - Synechococcus sp. (strain CC9311) Length = 336 Score = 112 bits (269), Expect = 1e-23 Identities = 56/119 (47%), Positives = 72/119 (60%) Frame = +1 Query: 406 NLNVQYLDLYLIHWPQAYKEDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIG 585 NL V YL+LYLIHWP + + + F + + +TW+AME +GL K IG Sbjct: 116 NLGVDYLNLYLIHWPVGIRPEKT-FAESVDDLLTPEESPISETWEAMESTRDKGLTKHIG 174 Query: 586 VSNFNSKQLERLLQHATVKPVVNQVECHPYLNQKRLKEFCEARGVKITXYSPLGSPDRP 762 VSNF K+L++L+ H KP VNQVE HP L Q L E+C + + IT YSPLGS DRP Sbjct: 175 VSNFTVKKLQQLVSHCKQKPEVNQVEHHPLLQQPTLIEYCASEEILITAYSPLGSMDRP 233 Score = 78.6 bits (185), Expect = 2e-13 Identities = 42/112 (37%), Positives = 56/112 (50%) Frame = +3 Query: 66 RSSQAAAQLINKMAPXIPVVXFXXGASXPVFGXGXWXSKPGXVXXAVKXAIDIGXRHIDC 245 R + I + P + G P+ G G S+ V +V+ AI IG RHIDC Sbjct: 3 RDLSTSVNNIKDVIPTMQYASLSNGDRMPLLGLGTGKSESRQVYKSVREAIKIGYRHIDC 62 Query: 246 AYVYGNXXXVGXAITSKIKEGVVTRXXLFITSKLWNTFHRPDLVRGALQEXL 401 A +YGN VG AI I+ +TR L+ITSKLW+ H + V AL + L Sbjct: 63 ASIYGNEEEVGDAIRDAIQNHEITRSELWITSKLWSNCHGKNHVEAALSQSL 114 >UniRef50_A2QL02 Cluster: Putative frameshift; n=1; Aspergillus niger|Rep: Putative frameshift - Aspergillus niger Length = 357 Score = 112 bits (269), Expect = 1e-23 Identities = 49/123 (39%), Positives = 78/123 (63%) Frame = +1 Query: 406 NLNVQYLDLYLIHWPQAYKEDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIG 585 +L Y+DL L+H+P +K FP D G++ + +VDTW+A+E +VK G V++IG Sbjct: 127 DLYTPYVDLLLMHYPCTFKRGEDRFPRDAEGRMIHGETTFVDTWRALEKVVKTGKVRAIG 186 Query: 586 VSNFNSKQLERLLQHATVKPVVNQVECHPYLNQKRLKEFCEARGVKITXYSPLGSPDRPW 765 VSNF+ ++E LL+ + P V+Q+E HPYL QK E+ +G+ + +SPLG+ + + Sbjct: 187 VSNFSKGEIETLLRETSTVPAVHQMEVHPYLQQKGFNEWLREKGIHVVQFSPLGNMNDFY 246 Query: 766 GQA 774 QA Sbjct: 247 RQA 249 Score = 42.7 bits (96), Expect = 0.012 Identities = 33/89 (37%), Positives = 41/89 (46%), Gaps = 1/89 (1%) Frame = +3 Query: 138 GASXPVFGXGXWXSKPGXVXXAVKXAIDIGXRHIDCAYVYGNXXXVGXAITSKIKEGVVT 317 GA P G G + P V + G R ID A VYG VG I K+ V Sbjct: 43 GAKIPALGVGTFQD-PDSQEETVCQVLQRGMRLIDTARVYGVEQQVGRGI----KKSGVP 97 Query: 318 RXXLFITSKLW-NTFHRPDLVRGALQEXL 401 R +F+ +KLW N FH PD V A+ + L Sbjct: 98 REEIFLGTKLWCNDFH-PDDVERAVDDSL 125 >UniRef50_A3U9Y0 Cluster: Aldehyde reductase; n=5; Bacteroidetes|Rep: Aldehyde reductase - Croceibacter atlanticus HTCC2559 Length = 316 Score = 111 bits (268), Expect = 2e-23 Identities = 53/121 (43%), Positives = 71/121 (58%) Frame = +1 Query: 406 NLNVQYLDLYLIHWPQAYKEDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIG 585 +LN+ YLDLYL+HWP A+K + FP + + +T AM K+GL+K +G Sbjct: 98 DLNLDYLDLYLMHWPVAFKPSVNGFPEKDEDYLSLEEAPLHETLNAMIEAKKQGLIKHVG 157 Query: 586 VSNFNSKQLERLLQHATVKPVVNQVECHPYLNQKRLKEFCEARGVKITXYSPLGSPDRPW 765 VSNF+ ++LE L P +NQVE HPYL Q L +C G+ +T YSPLGS DR Sbjct: 158 VSNFSKEKLESLKGKVEEMPEMNQVELHPYLPQNDLYSYCSKEGILLTGYSPLGSGDRSE 217 Query: 766 G 768 G Sbjct: 218 G 218 Score = 81.4 bits (192), Expect = 3e-14 Identities = 40/91 (43%), Positives = 50/91 (54%) Frame = +3 Query: 129 FXXGASXPVFGXGXWXSKPGXVXXAVKXAIDIGXRHIDCAYVYGNXXXVGXAITSKIKEG 308 F G S P G G W S P V AVK A++ G +HIDCA Y N VG A + G Sbjct: 6 FRDGDSIPSIGLGTWKSDPEDVKKAVKIALENGYKHIDCAAAYDNEDAVGEAFKESFESG 65 Query: 309 VVTRXXLFITSKLWNTFHRPDLVRGALQEXL 401 V R +F+TSKLWN H+ + V AL++ L Sbjct: 66 NVKREDIFVTSKLWNNAHKKEDVIPALKKTL 96 >UniRef50_Q9U2J5 Cluster: Putative uncharacterized protein; n=2; Caenorhabditis|Rep: Putative uncharacterized protein - Caenorhabditis elegans Length = 339 Score = 111 bits (266), Expect = 3e-23 Identities = 47/116 (40%), Positives = 79/116 (68%), Gaps = 5/116 (4%) Frame = +1 Query: 421 YLDLYLIHWPQAYKEDG-----SLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIG 585 Y+DL +IHWP + ED L+P +GK+++SDVDY++TWKA+E + G ++SIG Sbjct: 106 YMDLIVIHWPFGWAEDEPPGERGLWPRGANGKMRYSDVDYLETWKALEDAHRSGKIRSIG 165 Query: 586 VSNFNSKQLERLLQHATVKPVVNQVECHPYLNQKRLKEFCEARGVKITXYSPLGSP 753 ++NFN Q+E++ +KP V QVE +P+L+Q+ +++FC +G+ +T + G+P Sbjct: 166 LANFNIGQVEQVWTKGLIKPAVLQVEMNPFLDQEEIRQFCREKGIILTAFMLTGNP 221 Score = 60.1 bits (139), Expect = 8e-08 Identities = 32/98 (32%), Positives = 42/98 (42%) Frame = +3 Query: 108 PXIPVVXFXXGASXPVFGXGXWXSKPGXVXXAVKXAIDIGXRHIDCAYVYGNXXXVGXAI 287 P V G PV G G W V+ A++ G RHID A + N V I Sbjct: 2 PIADTVTLNSGYEMPVIGYGTWQLPKNLAAERVRDALEAGYRHIDSALSFKNQEEVAAGI 61 Query: 288 TSKIKEGVVTRXXLFITSKLWNTFHRPDLVRGALQEXL 401 K V R LF++SK+WNT+H + + E L Sbjct: 62 KDWCKIRKVRREELFLSSKIWNTYHSRNRCMQQIDEML 99 >UniRef50_Q7G764 Cluster: Probable NAD(P)H-dependent oxidoreductase 1; n=32; Eukaryota|Rep: Probable NAD(P)H-dependent oxidoreductase 1 - Oryza sativa subsp. japonica (Rice) Length = 321 Score = 111 bits (266), Expect = 3e-23 Identities = 53/123 (43%), Positives = 76/123 (61%) Frame = +1 Query: 406 NLNVQYLDLYLIHWPQAYKEDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIG 585 NL + Y+DL L+HWP + FP + + D++ V W+ ME + GL ++IG Sbjct: 106 NLGMDYVDLLLVHWPVSLTPGNYDFPFPKEVILPSFDMEGV--WRGMEECHRLGLARAIG 163 Query: 586 VSNFNSKQLERLLQHATVKPVVNQVECHPYLNQKRLKEFCEARGVKITXYSPLGSPDRPW 765 VSNF++K+LE+LL A V+P VNQVE +P Q+ L+E C GV++ YSPLG+ PW Sbjct: 164 VSNFSAKKLEQLLSLAAVRPAVNQVEVNPMWQQRTLREVCRREGVQLCGYSPLGAKGTPW 223 Query: 766 GQA 774 G A Sbjct: 224 GSA 226 Score = 46.8 bits (106), Expect = 8e-04 Identities = 19/51 (37%), Positives = 32/51 (62%), Gaps = 1/51 (1%) Frame = +3 Query: 201 AVKXAIDIGXRHIDCAYVYGNXXXVGXAITSKIKEGVV-TRXXLFITSKLW 350 A+ AI++G RH D A +Y VG A+ ++ G++ +R +F+TSK+W Sbjct: 37 AMLRAIELGYRHFDTARIYATEGCVGEAVAEAVRRGLIASRADVFVTSKIW 87 >UniRef50_Q6TY50 Cluster: Reductase 2; n=10; Magnoliophyta|Rep: Reductase 2 - Hydrangea macrophylla (Bigleaf hydrangea) Length = 321 Score = 110 bits (265), Expect = 4e-23 Identities = 54/124 (43%), Positives = 76/124 (61%) Frame = +1 Query: 406 NLNVQYLDLYLIHWPQAYKEDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIG 585 NL ++Y+D+YLIHWP + K +P K F +DY W+AME K GL K+IG Sbjct: 107 NLKLEYIDMYLIHWPVSSKPGNYEYPIK---KEDFLQMDYKSVWEAMEECQKLGLTKAIG 163 Query: 586 VSNFNSKQLERLLQHATVKPVVNQVECHPYLNQKRLKEFCEARGVKITXYSPLGSPDRPW 765 VSNF+ K+L +L +A V P VNQVE +P QK+L EFC++ G+ + Y+ LG+ + Sbjct: 164 VSNFSCKKLSDVLANAKVPPAVNQVEVNPCWQQKQLTEFCKSNGILVVAYAALGAVGTFY 223 Query: 766 GQAR 777 G R Sbjct: 224 GTNR 227 Score = 57.2 bits (132), Expect = 5e-07 Identities = 40/105 (38%), Positives = 52/105 (49%), Gaps = 5/105 (4%) Frame = +3 Query: 102 MAPXIPVVXFXXGA-SXPVFGXGXWXSKP---GXVXXAVKXAIDIGXRHIDCAYVYGNXX 269 MA IP V G PV G G P V AV A+ +G RH D A +Y + Sbjct: 1 MAFTIPEVPLSSGGRKMPVLGLGTAADPPVDPETVRKAVTEALKLGYRHFDTAALYNSEQ 60 Query: 270 XVGXAITSKIKEGVV-TRXXLFITSKLWNTFHRPDLVRGALQEXL 401 +G AI + EG++ +R LFITSKLW + + V ALQ+ L Sbjct: 61 PLGDAIAEALGEGLIKSRDELFITSKLWCSDAHRENVEPALQKTL 105 >UniRef50_A2EHN6 Cluster: Oxidoreductase, aldo/keto reductase family protein; n=10; Trichomonas vaginalis|Rep: Oxidoreductase, aldo/keto reductase family protein - Trichomonas vaginalis G3 Length = 312 Score = 110 bits (265), Expect = 4e-23 Identities = 50/119 (42%), Positives = 78/119 (65%), Gaps = 4/119 (3%) Frame = +1 Query: 409 LNVQYLDLYLIHWPQAYK----EDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVK 576 L + Y+DL+LIH P A+K +DG++ P D+ GKIQ+ +D ++T+ AME K+GL + Sbjct: 92 LQLSYVDLFLIHQPIAFKSLPAKDGTMMPKDEKGKIQYEQIDILETYHAMEECQKKGLTR 151 Query: 577 SIGVSNFNSKQLERLLQHATVKPVVNQVECHPYLNQKRLKEFCEARGVKITXYSPLGSP 753 IGVSNF+ +QLER+ + +KP NQVEC+ Y K L +CE+ + + ++ +G P Sbjct: 152 HIGVSNFSIEQLERIWFNCEIKPYANQVECNIYRQFKPLLSYCESHNIYLMAHTTIGHP 210 Score = 63.7 bits (148), Expect = 6e-09 Identities = 35/92 (38%), Positives = 48/92 (52%), Gaps = 2/92 (2%) Frame = +3 Query: 150 PVFGXGXWXSK-PGXVXXAVKXAID-IGXRHIDCAYVYGNXXXVGXAITSKIKEGVVTRX 323 P G G + + P + A+ AI+ G RHID A+ Y N +G + +G + R Sbjct: 4 PQLGFGTYLANDPAKLKAALHYAIEECGVRHIDTAFAYYNQNVIGETLKEIFAKGKIKRE 63 Query: 324 XLFITSKLWNTFHRPDLVRGALQEXLXQSERS 419 +FIT+KLW T HR DLV L E L Q + S Sbjct: 64 DMFITTKLWCTHHRKDLVEPELHENLAQLQLS 95 >UniRef50_Q7G765 Cluster: Probable NAD(P)H-dependent oxidoreductase 2; n=6; Magnoliophyta|Rep: Probable NAD(P)H-dependent oxidoreductase 2 - Oryza sativa subsp. japonica (Rice) Length = 322 Score = 110 bits (264), Expect = 5e-23 Identities = 52/123 (42%), Positives = 73/123 (59%) Frame = +1 Query: 406 NLNVQYLDLYLIHWPQAYKEDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIG 585 NL + Y+DL L+HWP FP + D++ V W+ ME + GL ++IG Sbjct: 108 NLGMDYVDLLLVHWPATVAPGSYDFPFPKEEMAPAFDMEGV--WRGMEECHRLGLARAIG 165 Query: 586 VSNFNSKQLERLLQHATVKPVVNQVECHPYLNQKRLKEFCEARGVKITXYSPLGSPDRPW 765 VSNF++K+LE+LL A V+P NQVE +P Q+ L+E C GV++ YSPLG+ PW Sbjct: 166 VSNFSAKKLEQLLSFAVVRPAANQVEMNPMWQQRTLREVCRREGVQLCGYSPLGAKGTPW 225 Query: 766 GQA 774 G A Sbjct: 226 GSA 228 Score = 45.6 bits (103), Expect = 0.002 Identities = 30/90 (33%), Positives = 46/90 (51%), Gaps = 5/90 (5%) Frame = +3 Query: 201 AVKXAIDIGXRHIDCAYVYGNXXXVGXAITSKIKEGVV-TRXXLFITSKLW-NTFHRPDL 374 A+ AI++G RH D A +Y V A+ ++ G+V +R +F+TSKLW + H + Sbjct: 39 ALLRAIELGYRHFDTARLYATEGCVSEAVAEAVRRGLVASRADVFVTSKLWCSDLHAGRV 98 Query: 375 V---RGALQEXLXQSERSVLGSVPDTLAPG 455 V R L+ +L P T+APG Sbjct: 99 VPAARETLRNLGMDYVDLLLVHWPATVAPG 128 >UniRef50_Q9FJK0 Cluster: Aldose reductase-like protein; n=3; core eudicotyledons|Rep: Aldose reductase-like protein - Arabidopsis thaliana (Mouse-ear cress) Length = 316 Score = 108 bits (260), Expect = 2e-22 Identities = 51/120 (42%), Positives = 74/120 (61%) Frame = +1 Query: 409 LNVQYLDLYLIHWPQAYKEDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGV 588 + + YLD YL+HWP K G P + + + D+ +TW+ ME ++ GL +SIGV Sbjct: 101 MGLDYLDNYLVHWPIKLKP-GVSEPIPKEDEFE-KDLGIEETWQGMERCLEMGLCRSIGV 158 Query: 589 SNFNSKQLERLLQHATVKPVVNQVECHPYLNQKRLKEFCEARGVKITXYSPLGSPDRPWG 768 SNF+SK++ LL A+V P VNQVE HP Q++L++ CE + ++ YSPLG P WG Sbjct: 159 SNFSSKKIFDLLDFASVSPSVNQVEMHPLWRQRKLRKVCEENNIHVSGYSPLGGPGNCWG 218 Score = 58.4 bits (135), Expect = 2e-07 Identities = 31/83 (37%), Positives = 42/83 (50%), Gaps = 2/83 (2%) Frame = +3 Query: 120 VVXFXXGASXPVFGXGXWXSKPGX--VXXAVKXAIDIGXRHIDCAYVYGNXXXVGXAITS 293 V G + P+ G G + + AV AI IG RH D A +YG+ +G A+ Sbjct: 5 VARLRCGETIPLLGMGTYCPQKDRESTISAVHQAIKIGYRHFDTAKIYGSEEALGTALGQ 64 Query: 294 KIKEGVVTRXXLFITSKLWNTFH 362 I G V R LF+TSKLW++ H Sbjct: 65 AISYGTVQRDDLFVTSKLWSSDH 87 >UniRef50_A7PNI3 Cluster: Chromosome chr1 scaffold_22, whole genome shotgun sequence; n=2; Vitis vinifera|Rep: Chromosome chr1 scaffold_22, whole genome shotgun sequence - Vitis vinifera (Grape) Length = 360 Score = 108 bits (260), Expect = 2e-22 Identities = 50/117 (42%), Positives = 75/117 (64%), Gaps = 1/117 (0%) Frame = +1 Query: 406 NLNVQYLDLYLIHWPQAYKEDGSLFPTDQSGKIQFSDVDYVD-TWKAMEPLVKEGLVKSI 582 NL V YLDLYL+HWP + P SG ++ + WKAME L++ GLV++I Sbjct: 105 NLGVTYLDLYLMHWPDITAFGDATDPPSNSGNDHRQFLNRLKKAWKAMEGLIELGLVRAI 164 Query: 583 GVSNFNSKQLERLLQHATVKPVVNQVECHPYLNQKRLKEFCEARGVKITXYSPLGSP 753 GVSNF +Q++ LL+ A + P VNQV+ HP+ Q L +FC+++G+ ++ ++PLG P Sbjct: 165 GVSNFGVQQIKELLKFAKIVPAVNQVKLHPFWRQDELVKFCQSKGIHVSAHTPLGVP 221 Score = 58.8 bits (136), Expect = 2e-07 Identities = 31/87 (35%), Positives = 45/87 (51%) Frame = +3 Query: 141 ASXPVFGXGXWXSKPGXVXXAVKXAIDIGXRHIDCAYVYGNXXXVGXAITSKIKEGVVTR 320 A P G G W S AVK A+ G R IDCA++YGN VG A+ G + R Sbjct: 18 AKIPAIGLGTWQSGGDLCVEAVKRALSEGYRQIDCAHLYGNEVEVGEALAEAF-NGSLKR 76 Query: 321 XXLFITSKLWNTFHRPDLVRGALQEXL 401 +F+TSKL+ T + + + +++ L Sbjct: 77 EDVFLTSKLYCTMNSLNKIENSVRVSL 103 >UniRef50_P27800 Cluster: Aldehyde reductase 1; n=18; root|Rep: Aldehyde reductase 1 - Sporobolomyces salmonicolor Length = 323 Score = 108 bits (259), Expect = 2e-22 Identities = 54/119 (45%), Positives = 77/119 (64%), Gaps = 5/119 (4%) Frame = +1 Query: 409 LNVQYLDLYLIHWPQAYKEDG----SLFPTDQSGKIQFS-DVDYVDTWKAMEPLVKEGLV 573 L ++YLDLYLIHWP A+ +G +LFP +++ +V VDTWKAM L+ G V Sbjct: 96 LGLEYLDLYLIHWPVAFPPEGDITQNLFPKANDKEVKLDLEVSLVDTWKAMVKLLDTGKV 155 Query: 574 KSIGVSNFNSKQLERLLQHATVKPVVNQVECHPYLNQKRLKEFCEARGVKITXYSPLGS 750 K+IGVSNF++K ++ +++ V P VNQ+E HP L Q L +A+ + IT YSPLG+ Sbjct: 156 KAIGVSNFDAKMVDAIIEATGVTPSVNQIERHPLLLQPELIAHHKAKNIHITAYSPLGN 214 Score = 84.6 bits (200), Expect = 3e-15 Identities = 45/90 (50%), Positives = 52/90 (57%) Frame = +3 Query: 138 GASXPVFGXGXWXSKPGXVXXAVKXAIDIGXRHIDCAYVYGNXXXVGXAITSKIKEGVVT 317 GAS + G G W + PG V VK AI+ G RH+D A VY N VG A IKE V Sbjct: 10 GASLELVGYGTWQAAPGEVGQGVKVAIETGYRHLDLAKVYSNQPEVGAA----IKEAGVK 65 Query: 318 RXXLFITSKLWNTFHRPDLVRGALQEXLXQ 407 R LFITSKLWN HRP+ V AL + L + Sbjct: 66 REDLFITSKLWNNSHRPEQVEPALDDTLKE 95 >UniRef50_Q9VHX4 Cluster: CG2767-PA; n=4; Endopterygota|Rep: CG2767-PA - Drosophila melanogaster (Fruit fly) Length = 329 Score = 107 bits (258), Expect = 3e-22 Identities = 53/118 (44%), Positives = 77/118 (65%), Gaps = 3/118 (2%) Frame = +1 Query: 406 NLNVQYLDLYLIHWPQAYK--EDGSLFPTDQSGKIQFS-DVDYVDTWKAMEPLVKEGLVK 576 +L + Y+DLYL+H P EDGS F D+ G ++ ++ W AME LV++GL K Sbjct: 101 DLQLDYVDLYLVHTPFTININEDGS-FKLDKEGLMEVDVTTNHAAIWVAMEALVEKGLTK 159 Query: 577 SIGVSNFNSKQLERLLQHATVKPVVNQVECHPYLNQKRLKEFCEARGVKITXYSPLGS 750 SIGVSNF+ Q+ RLL++ ++P NQ+E H YL Q+ L +FC++ + +T YSPLGS Sbjct: 160 SIGVSNFSKDQVARLLKNCKIRPANNQIEHHVYLQQRDLVDFCKSENITVTAYSPLGS 217 Score = 61.7 bits (143), Expect = 2e-08 Identities = 31/91 (34%), Positives = 45/91 (49%) Frame = +3 Query: 129 FXXGASXPVFGXGXWXSKPGXVXXAVKXAIDIGXRHIDCAYVYGNXXXVGXAITSKIKEG 308 F G PV G G W + + A+ A++ G RHID A VYGN +G + + G Sbjct: 9 FNNGEKMPVIGIGTWQASDEEIETAIDAALEAGYRHIDTAPVYGNEKAIGRVLKRWLDAG 68 Query: 309 VVTRXXLFITSKLWNTFHRPDLVRGALQEXL 401 V R LFI +K+ +RP V +++ L Sbjct: 69 KVKREELFIVTKVPPVSNRPHEVEPTIKKSL 99 Score = 37.9 bits (84), Expect = 0.35 Identities = 20/44 (45%), Positives = 26/44 (59%) Frame = +2 Query: 764 GAKPDDPQXMEDPKLKXIADRLGKTVAQVLIRYQIDXGXIVXPE 895 G D P M+ P++K IA GKT AQVL+R+ ID G P+ Sbjct: 228 GIVRDLPDLMDIPEVKEIAASHGKTPAQVLLRWIIDTGVSAIPK 271 >UniRef50_UPI0000519CC2 Cluster: PREDICTED: similar to CG2767-PA; n=1; Apis mellifera|Rep: PREDICTED: similar to CG2767-PA - Apis mellifera Length = 321 Score = 107 bits (256), Expect = 5e-22 Identities = 52/117 (44%), Positives = 77/117 (65%), Gaps = 2/117 (1%) Frame = +1 Query: 406 NLNVQYLDLYLIHWPQAYKEDGS-LFPTDQSGKIQFSD-VDYVDTWKAMEPLVKEGLVKS 579 NL ++YLDLYLIH P +++ G L P D++G I+ + ++V+ W ME VK G K+ Sbjct: 100 NLRLEYLDLYLIHVPIGFEKVGDILHPFDENGHIRLDNSTNHVEIWAEMEKQVKCGRTKA 159 Query: 580 IGVSNFNSKQLERLLQHATVKPVVNQVECHPYLNQKRLKEFCEARGVKITXYSPLGS 750 IG+SNFN Q++R+L++ +K + Q+E H Y QK L +FC+ + IT YSPLGS Sbjct: 160 IGLSNFNISQIKRILKNTKMKISMLQIELHVYFQQKELVKFCKQENIPITAYSPLGS 216 Score = 45.2 bits (102), Expect = 0.002 Identities = 21/70 (30%), Positives = 34/70 (48%) Frame = +3 Query: 138 GASXPVFGXGXWXSKPGXVXXAVKXAIDIGXRHIDCAYVYGNXXXVGXAITSKIKEGVVT 317 G P+ G G W ++ + A+ A++ G RHID A Y N +G + + + Sbjct: 11 GELMPIIGFGTWQAQEKELEDALNIALEAGYRHIDTATSYENEKVIGDVLKNWFDSKKLK 70 Query: 318 RXXLFITSKL 347 R +FI +KL Sbjct: 71 RSDIFIVTKL 80 >UniRef50_Q68ST9 Cluster: Reductase AKOR2; n=2; Pleurotus djamor|Rep: Reductase AKOR2 - Pleurotus djamor Length = 306 Score = 106 bits (255), Expect = 7e-22 Identities = 50/116 (43%), Positives = 76/116 (65%), Gaps = 2/116 (1%) Frame = +1 Query: 406 NLNVQYLDLYLIHWPQ-AYKEDGSLFPTDQSGKIQFSDVDYV-DTWKAMEPLVKEGLVKS 579 NL +Y+DLYL+H+PQ + ++ + FP + G I+ + + D W +E L+ G VK+ Sbjct: 99 NLGTEYIDLYLVHFPQRVFYDETTDFPRNPDGSIKVVNSPTLNDVWADVETLLDTGKVKA 158 Query: 580 IGVSNFNSKQLERLLQHATVKPVVNQVECHPYLNQKRLKEFCEARGVKITXYSPLG 747 IGVSN++ K LE LL+ A V P VNQVE HP+L Q +L +C+ +G+ +T Y+P G Sbjct: 159 IGVSNYSIKTLEELLKTAKVVPAVNQVELHPFLAQSKLLAYCKEKGIAVTAYTPTG 214 >UniRef50_Q41399 Cluster: Chalcone reductase; n=4; eudicotyledons|Rep: Chalcone reductase - Sesbania rostrata Length = 322 Score = 106 bits (254), Expect = 9e-22 Identities = 52/120 (43%), Positives = 73/120 (60%) Frame = +1 Query: 409 LNVQYLDLYLIHWPQAYKEDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGV 588 L ++Y+DLYLIHWP + D L K D TWKAME + GL KSIG+ Sbjct: 108 LGMEYVDLYLIHWPVRLRHD--LENPVIFSKEDLLPFDIEGTWKAMEECYRLGLAKSIGI 165 Query: 589 SNFNSKQLERLLQHATVKPVVNQVECHPYLNQKRLKEFCEARGVKITXYSPLGSPDRPWG 768 N+ +K+L +LL+ AT+ P VNQVE +P Q L+EFC+ +G+ ++ +SPLG+ WG Sbjct: 166 CNYGTKKLTKLLEIATIPPAVNQVEMNPSWQQGNLREFCKQKGIHVSAWSPLGAYKIFWG 225 Score = 62.1 bits (144), Expect = 2e-08 Identities = 39/100 (39%), Positives = 52/100 (52%), Gaps = 4/100 (4%) Frame = +3 Query: 114 IPVVXFXXGASXPVFGXGXWX-SKPGXVXXA--VKXAIDIGXRHIDCAYVYGNXXXVGXA 284 IP V G PV G G S+P A AI +G RH D A VYG +G A Sbjct: 6 IPEVLLNSGHKMPVIGMGTSVESRPSNDVLASIFVDAIQVGYRHFDSASVYGTEEAIGMA 65 Query: 285 ITSKIKEGVV-TRXXLFITSKLWNTFHRPDLVRGALQEXL 401 ++ I++G++ +R +FITSK WNT DL+ AL+ L Sbjct: 66 VSKAIEQGLIKSRDEVFITSKPWNTDAHHDLIVPALKTTL 105 >UniRef50_UPI0000498F1F Cluster: oxidoreductase, aldo/keto reductase family; n=2; Entamoeba histolytica HM-1:IMSS|Rep: oxidoreductase, aldo/keto reductase family - Entamoeba histolytica HM-1:IMSS Length = 305 Score = 105 bits (253), Expect = 1e-21 Identities = 54/122 (44%), Positives = 73/122 (59%) Frame = +1 Query: 388 CRXPWXNLNVQYLDLYLIHWPQAYKEDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEG 567 C L ++YLDLY+IH P L ++G+ + +TW+ ME LV+EG Sbjct: 93 CLESLKKLQLEYLDLYIIHIP--------LTADKKTGEFTEEIIPIEETWREMEKLVEEG 144 Query: 568 LVKSIGVSNFNSKQLERLLQHATVKPVVNQVECHPYLNQKRLKEFCEARGVKITXYSPLG 747 LVKSIGVSNFN K+LE LL A ++P VNQ E H Y + +L +FC+ + IT Y PLG Sbjct: 145 LVKSIGVSNFNIKKLEELLAIAKIQPAVNQFEFHIYYQRPKLHQFCKKHNIHITGYCPLG 204 Query: 748 SP 753 +P Sbjct: 205 NP 206 Score = 79.8 bits (188), Expect = 9e-14 Identities = 43/96 (44%), Positives = 51/96 (53%) Frame = +3 Query: 138 GASXPVFGXGXWXSKPGXVXXAVKXAIDIGXRHIDCAYVYGNXXXVGXAITSKIKEGVVT 317 G P G G W S G V AV+ AI G RHIDCA YGN VG I S I +G V Sbjct: 10 GYKIPKLGLGTWMSANGEVGKAVEIAIKNGYRHIDCAKAYGNEKEVGDGIKSAIAKGYVK 69 Query: 318 RXXLFITSKLWNTFHRPDLVRGALQEXLXQSERSVL 425 R LF+T+KLW+T + VR A E L + + L Sbjct: 70 REELFVTTKLWSTDKHKEDVRPACLESLKKLQLEYL 105 >UniRef50_Q7PLK6 Cluster: CG40064-PA; n=1; Drosophila melanogaster|Rep: CG40064-PA - Drosophila melanogaster (Fruit fly) Length = 361 Score = 105 bits (252), Expect = 2e-21 Identities = 52/112 (46%), Positives = 73/112 (65%), Gaps = 2/112 (1%) Frame = +1 Query: 388 CRXPWXNLNVQYLDLYLIHWPQAYKE--DGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVK 561 C L Y+DLYL+H+P YK D L P ++Q ++DY+DTW+AME LVK Sbjct: 111 CEKQLELLGFSYIDLYLMHFPVGYKYVCDEILMPMS-GDELQTVEIDYLDTWRAMENLVK 169 Query: 562 EGLVKSIGVSNFNSKQLERLLQHATVKPVVNQVECHPYLNQKRLKEFCEARG 717 G+V+SIG+SNFN +Q++R++Q ++ KPVVNQVE P QK L ++C G Sbjct: 170 LGMVRSIGLSNFNMEQIQRIIQCSSSKPVVNQVEIWPGFLQKDLVDYCRYNG 221 Score = 65.3 bits (152), Expect = 2e-09 Identities = 30/67 (44%), Positives = 42/67 (62%) Frame = +3 Query: 201 AVKXAIDIGXRHIDCAYVYGNXXXVGXAITSKIKEGVVTRXXLFITSKLWNTFHRPDLVR 380 AV AI+ G RH D AY Y N +G A+ ++IK G ++R +F+T+KLWNT H P VR Sbjct: 49 AVHCAIETGFRHFDTAYYYENEKEIGEALRTQIKMGNISRENIFLTTKLWNTHHDPRDVR 108 Query: 381 GALQEXL 401 ++ L Sbjct: 109 RICEKQL 115 >UniRef50_P26690 Cluster: NAD(P)H-dependent 6'-deoxychalcone synthase; n=3; Papilionoideae|Rep: NAD(P)H-dependent 6'-deoxychalcone synthase - Glycine max (Soybean) Length = 315 Score = 105 bits (251), Expect = 2e-21 Identities = 51/112 (45%), Positives = 73/112 (65%) Frame = +1 Query: 409 LNVQYLDLYLIHWPQAYKEDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGV 588 L ++YLDLYLIHWP + + FP + + F D W++ME K GL K+IGV Sbjct: 110 LQLEYLDLYLIHWPLSSQPGKFSFPIEVEDLLPF---DVKGVWESMEECQKLGLTKAIGV 166 Query: 589 SNFNSKQLERLLQHATVKPVVNQVECHPYLNQKRLKEFCEARGVKITXYSPL 744 SNF+ K+L+ LL AT++PVV+QVE + QK+L+EFC+ G+ +T +SPL Sbjct: 167 SNFSVKKLQNLLSVATIRPVVDQVEMNLAWQQKKLREFCKENGIIVTAFSPL 218 Score = 57.2 bits (132), Expect = 5e-07 Identities = 29/67 (43%), Positives = 40/67 (59%) Frame = +3 Query: 201 AVKXAIDIGXRHIDCAYVYGNXXXVGXAITSKIKEGVVTRXXLFITSKLWNTFHRPDLVR 380 A+ A+ G RH D A YG+ +G A+ I G+V+R LF+TSKLW T + P LV Sbjct: 41 AIIEAVKQGYRHFDTAAAYGSEQALGEALKEAIHLGLVSRQDLFVTSKLWVTENHPHLVL 100 Query: 381 GALQEXL 401 AL++ L Sbjct: 101 PALRKSL 107 >UniRef50_Q2UGR1 Cluster: Aldo/keto reductase family proteins; n=2; Ascomycota|Rep: Aldo/keto reductase family proteins - Aspergillus oryzae Length = 323 Score = 104 bits (250), Expect = 3e-21 Identities = 49/117 (41%), Positives = 73/117 (62%), Gaps = 2/117 (1%) Frame = +1 Query: 406 NLNVQYLDLYLIHWPQAYKEDG-SLFPTDQSGK-IQFSDVDYVDTWKAMEPLVKEGLVKS 579 +L YLDLYLIHWP A++ +L P D K + ++V DTW A+E LV+ ++S Sbjct: 97 DLQTDYLDLYLIHWPVAFEHTNETLTPIDPVTKRFRLANVPIADTWAALEKLVEAKKIRS 156 Query: 580 IGVSNFNSKQLERLLQHATVKPVVNQVECHPYLNQKRLKEFCEARGVKITXYSPLGS 750 IG+SNF +++ LL+ A + P VNQ+E HPYL Q L ++ + + + YSPLG+ Sbjct: 157 IGISNFTQDKIDDLLKTAKIPPAVNQIEAHPYLQQPGLHKYLKEKNILSVAYSPLGN 213 Score = 72.1 bits (169), Expect = 2e-11 Identities = 40/96 (41%), Positives = 50/96 (52%) Frame = +3 Query: 138 GASXPVFGXGXWXSKPGXVXXAVKXAIDIGXRHIDCAYVYGNXXXVGXAITSKIKEGVVT 317 G + P G G W SKP V AV+ A+ G RHID A Y N VG + K+ V Sbjct: 12 GYNIPAIGLGTWLSKPHEVENAVEAALRAGYRHIDAAACYQNENEVG----NGWKKSGVP 67 Query: 318 RXXLFITSKLWNTFHRPDLVRGALQEXLXQSERSVL 425 R +FITSKLWNT H P+ V A+ + L + L Sbjct: 68 RDQIFITSKLWNTHHHPEHVEEAVNKTLKDLQTDYL 103 Score = 37.9 bits (84), Expect = 0.35 Identities = 16/38 (42%), Positives = 25/38 (65%) Frame = +2 Query: 782 PQXMEDPKLKXIADRLGKTVAQVLIRYQIDXGXIVXPE 895 P+ ++DP +K IAD+LGK A +LI + + G V P+ Sbjct: 219 PRVVDDPDVKAIADKLGKDPAALLISWAVQRGTAVLPK 256 >UniRef50_Q17G72 Cluster: Aldo-keto reductase; n=9; Endopterygota|Rep: Aldo-keto reductase - Aedes aegypti (Yellowfever mosquito) Length = 316 Score = 104 bits (249), Expect = 4e-21 Identities = 47/115 (40%), Positives = 72/115 (62%) Frame = +1 Query: 406 NLNVQYLDLYLIHWPQAYKEDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIG 585 +L ++Y+DLY +H P E F + + + D+V WKAME + + GL ++IG Sbjct: 101 DLQLEYVDLYHVHVPFTVPEVDGPFLVEDGLIVLETTTDHVALWKAMEEVYEAGLARNIG 160 Query: 586 VSNFNSKQLERLLQHATVKPVVNQVECHPYLNQKRLKEFCEARGVKITXYSPLGS 750 +SNFN +Q++R+L + +KP Q+E H YL Q L +FC+A G+ +T YSPLGS Sbjct: 161 LSNFNQRQIQRILDNCQIKPANLQIENHIYLQQPELVKFCKANGITVTAYSPLGS 215 Score = 57.2 bits (132), Expect = 5e-07 Identities = 28/75 (37%), Positives = 38/75 (50%) Frame = +3 Query: 123 VXFXXGASXPVFGXGXWXSKPGXVXXAVKXAIDIGXRHIDCAYVYGNXXXVGXAITSKIK 302 + F G + P G G W + V A+ A++ G RHID A VY N +G + + Sbjct: 7 ITFENGTTMPALGFGTWRASDEEVEKALNEALEAGYRHIDTAPVYLNEKTIGKVLKEWMD 66 Query: 303 EGVVTRXXLFITSKL 347 G VTR LFI +KL Sbjct: 67 AGKVTRDELFIVTKL 81 Score = 37.1 bits (82), Expect = 0.61 Identities = 15/38 (39%), Positives = 26/38 (68%) Frame = +2 Query: 782 PQXMEDPKLKXIADRLGKTVAQVLIRYQIDXGXIVXPE 895 P +++P +K IA++LGK+ AQVL+R+ + G P+ Sbjct: 227 PDLLDNPVVKDIAEKLGKSPAQVLLRHLLQRGISTIPK 264 >UniRef50_Q5KI95 Cluster: Aldo-keto reductase, putative; n=14; Dikarya|Rep: Aldo-keto reductase, putative - Cryptococcus neoformans (Filobasidiella neoformans) Length = 353 Score = 104 bits (249), Expect = 4e-21 Identities = 51/122 (41%), Positives = 69/122 (56%), Gaps = 3/122 (2%) Frame = +1 Query: 406 NLNVQYLDLYLIHWPQAYKEDGS--LFPTDQSGKIQFS-DVDYVDTWKAMEPLVKEGLVK 576 +L YLDLYLIHWP +G+ LFP G D D TW ME ++K+G K Sbjct: 127 SLQTDYLDLYLIHWPVRLAPNGTHPLFPVKPDGSRNLDWDWDQAKTWAQMEDVLKKGKAK 186 Query: 577 SIGVSNFNSKQLERLLQHATVKPVVNQVECHPYLNQKRLKEFCEARGVKITXYSPLGSPD 756 +IG+SN +E +++ V P VNQVE HPY Q L ++C+ +G+ + YSPLGS Sbjct: 187 AIGLSNAGIPIIEHIIKTGKVTPAVNQVELHPYCPQHALLKYCKEKGILLEAYSPLGSTS 246 Query: 757 RP 762 P Sbjct: 247 SP 248 Score = 65.3 bits (152), Expect = 2e-09 Identities = 33/75 (44%), Positives = 42/75 (56%) Frame = +3 Query: 138 GASXPVFGXGXWXSKPGXVXXAVKXAIDIGXRHIDCAYVYGNXXXVGXAITSKIKEGVVT 317 GAS P G G W +K G V AV A+ G RHID A Y N VG IK+ V Sbjct: 44 GASIPAIGLGTWQAKAGEVRQAVAHALKAGYRHIDGALCYQNEDEVGLG----IKDSGVP 99 Query: 318 RXXLFITSKLWNTFH 362 R +F+TSK+W+++H Sbjct: 100 RSEIFLTSKVWSSYH 114 >UniRef50_A5E082 Cluster: GCY protein; n=4; Saccharomycetales|Rep: GCY protein - Lodderomyces elongisporus (Yeast) (Saccharomyces elongisporus) Length = 295 Score = 103 bits (247), Expect = 6e-21 Identities = 52/119 (43%), Positives = 76/119 (63%), Gaps = 3/119 (2%) Frame = +1 Query: 409 LNVQYLDLYLIHWPQAYKEDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGL-VKSIG 585 L ++Y+DLYLIHWP + D + + D D+VDTW+ ++ + KEG VK+IG Sbjct: 102 LGLEYVDLYLIHWPLS---------VDPKTEKPYDDYDFVDTWRNLQKIYKEGKKVKAIG 152 Query: 586 VSNFNSKQLERLL--QHATVKPVVNQVECHPYLNQKRLKEFCEARGVKITXYSPLGSPD 756 VSNFN K+L++LL + V PV+NQ+E HP L Q L ++ +++ + IT YSPLG D Sbjct: 153 VSNFNKKKLDKLLNSEGVNVVPVINQIEAHPLLTQPDLFDYLKSKDIYITAYSPLGHAD 211 Score = 54.4 bits (125), Expect = 4e-06 Identities = 33/89 (37%), Positives = 43/89 (48%), Gaps = 1/89 (1%) Frame = +3 Query: 138 GASXPVFGXGXWXS-KPGXVXXAVKXAIDIGXRHIDCAYVYGNXXXVGXAITSKIKEGVV 314 G P G G W + + A A+ G +HID A YGN VG AI + V Sbjct: 17 GLKIPAIGLGTWLADEEDAAYKATLTALKNGYKHIDTAAAYGNEDQVGRAIA----DSGV 72 Query: 315 TRXXLFITSKLWNTFHRPDLVRGALQEXL 401 +R +F+T+KLWN H+ GAL E L Sbjct: 73 SRDEIFVTTKLWNDQHKDP--EGALDESL 99 >UniRef50_P23901 Cluster: Aldose reductase; n=9; Poaceae|Rep: Aldose reductase - Hordeum vulgare (Barley) Length = 320 Score = 103 bits (247), Expect = 6e-21 Identities = 51/118 (43%), Positives = 71/118 (60%) Frame = +1 Query: 406 NLNVQYLDLYLIHWPQAYKEDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIG 585 +L + Y+DLY IHWP K DG+ P + ++F D WK ME LVK+GLVK IG Sbjct: 109 DLQLDYIDLYHIHWPFRLK-DGAHMPPEAGEVLEF---DMEGVWKEMENLVKDGLVKDIG 164 Query: 586 VSNFNSKQLERLLQHATVKPVVNQVECHPYLNQKRLKEFCEARGVKITXYSPLGSPDR 759 V N+ +L RLL+ A + P V Q+E HP ++ E C+ G+ +T YSPLGS ++ Sbjct: 165 VCNYTVTKLNRLLRSAKIPPAVCQMEMHPGWKNDKIFEACKKHGIHVTAYSPLGSSEK 222 Score = 54.4 bits (125), Expect = 4e-06 Identities = 32/89 (35%), Positives = 47/89 (52%), Gaps = 1/89 (1%) Frame = +3 Query: 138 GASXPVFGXGXWXSKPGXVXXAVKXAI-DIGXRHIDCAYVYGNXXXVGXAITSKIKEGVV 314 G + P G G W + +V+ AI + G RH+D A YG VG + + ++ G + Sbjct: 21 GHAMPAVGLGTWRAG-SDTAHSVRTAITEAGYRHVDTAAEYGVEKEVGKGLKAAMEAG-I 78 Query: 315 TRXXLFITSKLWNTFHRPDLVRGALQEXL 401 R LF+TSK+W T P+ VR AL+ L Sbjct: 79 DRKDLFVTSKIWCTNLAPERVRPALENTL 107 >UniRef50_Q8SSK6 Cluster: ALDOSE REDUCTASE; n=1; Encephalitozoon cuniculi|Rep: ALDOSE REDUCTASE - Encephalitozoon cuniculi Length = 301 Score = 103 bits (246), Expect = 8e-21 Identities = 51/117 (43%), Positives = 69/117 (58%), Gaps = 2/117 (1%) Frame = +1 Query: 406 NLNVQYLDLYLIHWPQAYKE--DGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKS 579 +L + Y+DLYLIHWP + DG++ + K D V WK ME LV GL KS Sbjct: 99 DLQMDYVDLYLIHWPVTFDPAPDGTVESCGK--KYNVGKFDAVGVWKKMEALVDLGLAKS 156 Query: 580 IGVSNFNSKQLERLLQHATVKPVVNQVECHPYLNQKRLKEFCEARGVKITXYSPLGS 750 IG+SNF E++L + P Q+E HPYLNQK L EF +++G+++ YS LGS Sbjct: 157 IGISNFGKANTEKILGTCRICPAAIQIELHPYLNQKELVEFMKSKGIQVISYSSLGS 213 Score = 76.6 bits (180), Expect = 8e-13 Identities = 35/76 (46%), Positives = 44/76 (57%), Gaps = 1/76 (1%) Frame = +3 Query: 138 GASXPVFGXGXWXSKPGXVXX-AVKXAIDIGXRHIDCAYVYGNXXXVGXAITSKIKEGVV 314 G P G G W + V A++ A+ +G RHID A++YGN +G + EGVV Sbjct: 11 GKEIPTVGLGTWGMEDEAVLEGAIRNALSLGYRHIDTAFIYGNEKMIGNILKKLFDEGVV 70 Query: 315 TRXXLFITSKLWNTFH 362 R LFITSKLWNTFH Sbjct: 71 QRKDLFITSKLWNTFH 86 >UniRef50_Q2V420 Cluster: Uncharacterized protein At2g37770.1; n=1; Arabidopsis thaliana|Rep: Uncharacterized protein At2g37770.1 - Arabidopsis thaliana (Mouse-ear cress) Length = 283 Score = 102 bits (245), Expect = 1e-20 Identities = 51/108 (47%), Positives = 72/108 (66%) Frame = +1 Query: 406 NLNVQYLDLYLIHWPQAYKEDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIG 585 +L ++Y+DLYLIHWP K+ GS+ ++ VD TWKAME L G ++IG Sbjct: 102 DLQLEYVDLYLIHWPARIKK-GSVGIKPEN----LLPVDIPSTWKAMEALYDSGKARAIG 156 Query: 586 VSNFNSKQLERLLQHATVKPVVNQVECHPYLNQKRLKEFCEARGVKIT 729 VSNF++K+L LL+ A V P VNQVECHP Q +L+EFC+++GV ++ Sbjct: 157 VSNFSTKKLADLLELARVPPAVNQVECHPSWRQTKLQEFCKSKGVHLS 204 Score = 87.4 bits (207), Expect = 4e-16 Identities = 45/100 (45%), Positives = 52/100 (52%) Frame = +3 Query: 102 MAPXIPVVXFXXGASXPVFGXGXWXSKPGXVXXAVKXAIDIGXRHIDCAYVYGNXXXVGX 281 MA I GA P G G W + PG V AV A+ IG RHIDCA +YGN +G Sbjct: 1 MANAITFFKLNTGAKFPSVGLGTWQASPGLVGDAVAAAVKIGYRHIDCAQIYGNEKEIGA 60 Query: 282 AITSKIKEGVVTRXXLFITSKLWNTFHRPDLVRGALQEXL 401 + ++ VV R LFITSKLW T H P V AL L Sbjct: 61 VLKKLFEDRVVKREDLFITSKLWCTDHDPQDVPEALNRTL 100 >UniRef50_Q05KR9 Cluster: Benzil reductase; n=5; Bacillales|Rep: Benzil reductase - Bacillus subtilis Length = 276 Score = 101 bits (242), Expect = 3e-20 Identities = 52/112 (46%), Positives = 72/112 (64%) Frame = +1 Query: 409 LNVQYLDLYLIHWPQAYKEDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGV 588 L + YLDLYLIHWP GK + Y DTW+A+E L K+G +++IGV Sbjct: 101 LQLDYLDLYLIHWP---------------GKDK-----YKDTWRALEKLYKDGKIRAIGV 140 Query: 589 SNFNSKQLERLLQHATVKPVVNQVECHPYLNQKRLKEFCEARGVKITXYSPL 744 SNF LE LL+ A +KP+VNQVE HP L QK L+++C+A+G+++ +SPL Sbjct: 141 SNFQVHHLEELLKDAEIKPMVNQVEFHPRLTQKELRDYCKAQGIQLEAWSPL 192 Score = 50.8 bits (116), Expect = 5e-05 Identities = 36/102 (35%), Positives = 46/102 (45%), Gaps = 1/102 (0%) Frame = +3 Query: 123 VXFXXGASXPVFGXGXWXSKPGX-VXXAVKXAIDIGXRHIDCAYVYGNXXXVGXAITSKI 299 V G P FG G + + G +VK AI G R ID A +Y N VG I Sbjct: 9 VKLHNGVEMPWFGLGVFKVENGNEATESVKAAIKNGYRSIDTAAIYKNEEGVGIGI---- 64 Query: 300 KEGVVTRXXLFITSKLWNTFHRPDLVRGALQEXLXQSERSVL 425 KE V R LFITSK+WN + A ++ L + + L Sbjct: 65 KESGVAREELFITSKVWNEDQGYETTLAAFEKSLERLQLDYL 106 >UniRef50_Q6CFG7 Cluster: Yarrowia lipolytica chromosome B of strain CLIB122 of Yarrowia lipolytica; n=9; Ascomycota|Rep: Yarrowia lipolytica chromosome B of strain CLIB122 of Yarrowia lipolytica - Yarrowia lipolytica (Candida lipolytica) Length = 337 Score = 101 bits (241), Expect = 3e-20 Identities = 52/121 (42%), Positives = 68/121 (56%), Gaps = 3/121 (2%) Frame = +1 Query: 409 LNVQYLDLYLIHWPQAYKEDGS--LFPTDQSGKIQFSDV-DYVDTWKAMEPLVKEGLVKS 579 L + Y+D+ LIHWP +G+ ++P G + TWK ME ++K G KS Sbjct: 127 LGLDYVDMLLIHWPVPLNPNGNDPVYPLRPDGSRDIDESGSQPKTWKQMEAVLKTGKTKS 186 Query: 580 IGVSNFNSKQLERLLQHATVKPVVNQVECHPYLNQKRLKEFCEARGVKITXYSPLGSPDR 759 IGVSNF+ LE LL+ A V P VNQVE HP L Q L EFC+ + +T +SP GS Sbjct: 187 IGVSNFSIPYLEELLKEAEVVPAVNQVELHPLLPQLELMEFCKKNNIVMTAFSPFGSVGG 246 Query: 760 P 762 P Sbjct: 247 P 247 Score = 58.4 bits (135), Expect = 2e-07 Identities = 30/76 (39%), Positives = 43/76 (56%), Gaps = 1/76 (1%) Frame = +3 Query: 138 GASXPVFGXGXWXSKPGXVXXAVKXAI-DIGXRHIDCAYVYGNXXXVGXAITSKIKEGVV 314 G + P G G W S V AV+ A+ + G RHID A+ Y N VG I +++GV Sbjct: 39 GKTIPAIGLGTWKSTTEEVAGAVECALTEGGYRHIDTAFNYRNEDAVGLGIKRAMEKGV- 97 Query: 315 TRXXLFITSKLWNTFH 362 R +F+T+K+W T+H Sbjct: 98 KREDIFVTTKIWVTYH 113 >UniRef50_UPI0000E45E29 Cluster: PREDICTED: similar to aldose reductase; n=1; Strongylocentrotus purpuratus|Rep: PREDICTED: similar to aldose reductase - Strongylocentrotus purpuratus Length = 274 Score = 100 bits (240), Expect = 4e-20 Identities = 55/142 (38%), Positives = 76/142 (53%) Frame = +1 Query: 388 CRXPWXNLNVQYLDLYLIHWPQAYKEDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEG 567 C NL + Y+DLYL+HWP AY +AME LV G Sbjct: 77 CDITLKNLQLSYVDLYLMHWPMAY--------------------------QAMEKLVTSG 110 Query: 568 LVKSIGVSNFNSKQLERLLQHATVKPVVNQVECHPYLNQKRLKEFCEARGVKITXYSPLG 747 K+IG+SNF+ K ++R+++ AT++P QVE HP L Q++L EFC+ + +T YSPLG Sbjct: 111 KCKAIGLSNFSMKMMKRVIEKATIQPANLQVELHPLLTQEKLIEFCKEHNMTVTAYSPLG 170 Query: 748 SPDRPWGQARRPPXHGGPQTEG 813 +PDRPW + P P G Sbjct: 171 APDRPWVKDDDPKLMEDPIVTG 192 Score = 89.0 bits (211), Expect = 1e-16 Identities = 42/72 (58%), Positives = 45/72 (62%) Frame = +3 Query: 171 WXSKPGXVXXAVKXAIDIGXRHIDCAYVYGNXXXVGXAITSKIKEGVVTRXXLFITSKLW 350 W SKPG V AVK AID G RHIDCA+VYGN VG + K VV R +FITSKLW Sbjct: 5 WMSKPGQVEAAVKAAIDCGYRHIDCAHVYGNEAEVGAGLKEKFDANVVKREDIFITSKLW 64 Query: 351 NTFHRPDLVRGA 386 N H PD V A Sbjct: 65 NNKHHPDDVEQA 76 Score = 47.2 bits (107), Expect = 6e-04 Identities = 21/45 (46%), Positives = 30/45 (66%) Frame = +2 Query: 761 PGAKPDDPQXMEDPKLKXIADRLGKTVAQVLIRYQIDXGXIVXPE 895 P K DDP+ MEDP + IA + GK+ AQ+LIR+ ++ G I P+ Sbjct: 175 PWVKDDDPKLMEDPIVTGIATKKGKSPAQILIRFCLERGIICIPK 219 >UniRef50_P38115 Cluster: D-arabinose dehydrogenase [NAD(P)+] heavy chain; n=3; Saccharomycetaceae|Rep: D-arabinose dehydrogenase [NAD(P)+] heavy chain - Saccharomyces cerevisiae (Baker's yeast) Length = 344 Score = 100 bits (240), Expect = 4e-20 Identities = 54/130 (41%), Positives = 80/130 (61%), Gaps = 12/130 (9%) Frame = +1 Query: 409 LNVQYLDLYLIHWPQAYKE-------DGSL-FPTDQSGKIQFS-DVDYVDTWKAMEPLV- 558 L ++Y+DL L HWP +++ G + P D SGK ++ D DY++T+K +E + Sbjct: 120 LGLEYVDLLLQHWPLCFEKIKDPKGISGLVKTPVDDSGKTMYAADGDYLETYKQLEKIYL 179 Query: 559 --KEGLVKSIGVSNFNSKQLERLLQHATVKPVVNQVECHPYLNQKRLKEFCEARGVKITX 732 + V++IGVSNF+ + LERL++ VKP VNQVE HP+L Q L++FC + +T Sbjct: 180 DPNDHRVRAIGVSNFSIEYLERLIKECRVKPTVNQVETHPHLPQMELRKFCFMHDILLTA 239 Query: 733 YSPLGSPDRP 762 YSPLGS P Sbjct: 240 YSPLGSHGAP 249 Score = 53.6 bits (123), Expect = 7e-06 Identities = 36/102 (35%), Positives = 48/102 (47%), Gaps = 6/102 (5%) Frame = +3 Query: 63 LRSSQAAAQLI--NKMAPXIPVVXFXX--GASXPVFGXGXWX--SKPGXVXXAVKXAIDI 224 + SS A+ + I N + P + F G P G G K AVK AI Sbjct: 1 MSSSVASTENIVENMLHPKTTEIYFSLNNGVRIPALGLGTANPHEKLAETKQAVKAAIKA 60 Query: 225 GXRHIDCAYVYGNXXXVGXAITSKIKEGVVTRXXLFITSKLW 350 G RHID A+ Y VG AI +++G + R LFIT+K+W Sbjct: 61 GYRHIDTAWAYETEPFVGEAIKELLEDGSIKREDLFITTKVW 102 >UniRef50_Q1IN88 Cluster: Aldehyde reductase; n=5; Bacteria|Rep: Aldehyde reductase - Acidobacteria bacterium (strain Ellin345) Length = 313 Score = 100 bits (239), Expect = 6e-20 Identities = 48/119 (40%), Positives = 72/119 (60%), Gaps = 1/119 (0%) Frame = +1 Query: 409 LNVQYLDLYLIHWPQAYKEDGSLFPTDQSGKIQFSD-VDYVDTWKAMEPLVKEGLVKSIG 585 L + YLDLYLIH P A++ P DQ+G + + + V +TW A+E LV G ++IG Sbjct: 107 LGLDYLDLYLIHTPFAFQPGDEQDPRDQNGSVIYDEGVTLRETWSALENLVDRGRCRAIG 166 Query: 586 VSNFNSKQLERLLQHATVKPVVNQVECHPYLNQKRLKEFCEARGVKITXYSPLGSPDRP 762 +S+ + +L + + A +KP V QVE HPYL + L EFC+ G+ + ++PLG RP Sbjct: 167 LSDISMDRLAPIYEAARIKPAVVQVESHPYLPETELLEFCKRNGIVLLAFAPLGHGMRP 225 Score = 67.7 bits (158), Expect = 4e-10 Identities = 32/84 (38%), Positives = 43/84 (51%) Frame = +3 Query: 150 PVFGXGXWXSKPGXVXXAVKXAIDIGXRHIDCAYVYGNXXXVGXAITSKIKEGVVTRXXL 329 P G G + P A + A+ G RH DCA Y N VG A+ + G + R + Sbjct: 21 PALGFGTLIADPALTITATRDALAAGFRHFDCAERYRNEREVGEALRAGRAAGNIAREEI 80 Query: 330 FITSKLWNTFHRPDLVRGALQEXL 401 F+T+KLWNT HRP+ V A + L Sbjct: 81 FVTTKLWNTNHRPERVEPAFEASL 104 Score = 35.1 bits (77), Expect = 2.5 Identities = 13/32 (40%), Positives = 22/32 (68%) Frame = +2 Query: 782 PQXMEDPKLKXIADRLGKTVAQVLIRYQIDXG 877 P +EDP + +++R+GKT AQVL+ + + G Sbjct: 225 PGLLEDPVITSVSERVGKTAAQVLLSWAVQRG 256 >UniRef50_Q4PDR0 Cluster: Putative uncharacterized protein; n=1; Ustilago maydis|Rep: Putative uncharacterized protein - Ustilago maydis (Smut fungus) Length = 339 Score = 100 bits (239), Expect = 6e-20 Identities = 48/119 (40%), Positives = 73/119 (61%), Gaps = 6/119 (5%) Frame = +1 Query: 409 LNVQYLDLYLIHWPQAYKEDGSLFPTDQSGKIQFSD---VDYVDTWKAMEPLV---KEGL 570 L + Y+DL+L+HWPQ + +D F T +S ++ + +TW ME + +G Sbjct: 102 LGIDYIDLWLLHWPQGFTKDDGGFGTGESFGLEHQKHLGPTFNETWAKMEDVFLNSHKGK 161 Query: 571 VKSIGVSNFNSKQLERLLQHATVKPVVNQVECHPYLNQKRLKEFCEARGVKITXYSPLG 747 VK+IGVSNF+ K LE L + + V P VNQ+E HPYL + L ++C+ + + +T YSPLG Sbjct: 162 VKAIGVSNFSIKNLEILAKTSKVTPAVNQIEAHPYLPEHELVKYCKHKSIHVTAYSPLG 220 Score = 51.2 bits (117), Expect = 3e-05 Identities = 36/103 (34%), Positives = 48/103 (46%), Gaps = 5/103 (4%) Frame = +3 Query: 102 MAPXIPVVXFXXGASXPVFGXGXWXSKPG-----XVXXAVKXAIDIGXRHIDCAYVYGNX 266 MA IP GA P G G W +PG + A+ AI +G RH+D A Y N Sbjct: 1 MAANIPSFTLNTGAKLPSVGMGCWQGQPGPGRDNELVDALVRAIKVGYRHLDTATGYRNE 60 Query: 267 XXVGXAITSKIKEGVVTRXXLFITSKLWNTFHRPDLVRGALQE 395 VG A +++ V R +F+T+KL RP V +QE Sbjct: 61 AEVGQA----VRQSGVARSEIFVTTKL-----RPGGVHDVVQE 94 >UniRef50_Q4PAT5 Cluster: Putative uncharacterized protein; n=1; Ustilago maydis|Rep: Putative uncharacterized protein - Ustilago maydis (Smut fungus) Length = 700 Score = 100 bits (239), Expect = 6e-20 Identities = 49/121 (40%), Positives = 79/121 (65%), Gaps = 6/121 (4%) Frame = +1 Query: 406 NLNVQYLDLYLIHWPQAY-KEDGSLFPTDQSG---KIQFSDV--DYVDTWKAMEPLVKEG 567 +L YLDLYL+HWP A+ GS+ P+ +S ++ D+ D++ T++ ME +VK+G Sbjct: 102 DLGTDYLDLYLMHWPVAFLNSKGSMVPSIRSTGGHPVESEDLSRDFMATYRVMEEMVKKG 161 Query: 568 LVKSIGVSNFNSKQLERLLQHATVKPVVNQVECHPYLNQKRLKEFCEARGVKITXYSPLG 747 V++IGVSNFN ++ ++ A++KPVVNQVE + ++ + L+ + A GV + YSP G Sbjct: 162 KVRNIGVSNFNIRRTSEVVDEASIKPVVNQVEVNLGVHNEELRNYAHAHGVTLQAYSPFG 221 Query: 748 S 750 S Sbjct: 222 S 222 Score = 71.7 bits (168), Expect = 2e-11 Identities = 38/88 (43%), Positives = 46/88 (52%) Frame = +3 Query: 138 GASXPVFGXGXWXSKPGXVXXAVKXAIDIGXRHIDCAYVYGNXXXVGXAITSKIKEGVVT 317 GA P G G W AV AI G RHIDCA+ Y N A+ + IK+ V Sbjct: 17 GAQIPKLGFGTWKMSKEQATPAVAHAIKTGYRHIDCAWAYRNE----DAVAAGIKKAGVP 72 Query: 318 RXXLFITSKLWNTFHRPDLVRGALQEXL 401 R L++TSKLWN+FH P+ V AL L Sbjct: 73 RSQLWLTSKLWNSFHHPEHVEKALDASL 100 >UniRef50_Q9Y020 Cluster: 3-dehydroecdysone 3beta-reductase precursor; n=1; Spodoptera littoralis|Rep: 3-dehydroecdysone 3beta-reductase precursor - Spodoptera littoralis (Egyptian cotton leafworm) Length = 345 Score = 99 bits (238), Expect = 8e-20 Identities = 54/145 (37%), Positives = 77/145 (53%) Frame = +1 Query: 367 RTWCAVPCRXPWXNLNVQYLDLYLIHWPQAYKEDGSLFPTDQSGKIQFSDVDYVDTWKAM 546 R AV + + Y+DL+L+HWP A ED S S+ DY++TW+A Sbjct: 115 REQVAVAMKETLNKTGLDYVDLFLMHWPIALNEDYS-----------HSNTDYLETWRAT 163 Query: 547 EPLVKEGLVKSIGVSNFNSKQLERLLQHATVKPVVNQVECHPYLNQKRLKEFCEARGVKI 726 E +VK G KSIG+SNFN Q+ +LQ T+KPV Q+E HP + Q+ L + + G+ + Sbjct: 164 EEMVKLGYTKSIGLSNFNKLQVATVLQECTIKPVALQIEVHPQIIQEDLITYAKDEGIIV 223 Query: 727 TXYSPLGSPDRPWGQARRPPXHGGP 801 YSP GS + +G P P Sbjct: 224 MGYSPFGSLVKRFGMDLPGPKMDDP 248 Score = 71.3 bits (167), Expect = 3e-11 Identities = 35/82 (42%), Positives = 48/82 (58%) Frame = +3 Query: 165 GXWXSKPGXVXXAVKXAIDIGXRHIDCAYVYGNXXXVGXAITSKIKEGVVTRXXLFITSK 344 G SK + V AID+G RH D A +Y VG AI KI EGV+ R +F+T+K Sbjct: 48 GAVTSKDKQLRNVVMQAIDLGYRHFDTAAIYNTEAEVGEAIRMKIDEGVIKREDVFLTTK 107 Query: 345 LWNTFHRPDLVRGALQEXLXQS 410 LWNT H+ + V A++E L ++ Sbjct: 108 LWNTHHKREQVAVAMKETLNKT 129 >UniRef50_Q6RZX1 Cluster: Gld1; n=22; Pezizomycotina|Rep: Gld1 - Trichoderma atroviride (Hypocrea atroviridis) Length = 327 Score = 99 bits (238), Expect = 8e-20 Identities = 51/122 (41%), Positives = 72/122 (59%), Gaps = 4/122 (3%) Frame = +1 Query: 406 NLNVQYLDLYLIHWPQAYKEDGS-LFPTDQSGKIQFSDV---DYVDTWKAMEPLVKEGLV 573 NL V Y+DL+L+HWP A +++ GK + + TW+AME LV G+V Sbjct: 112 NLKVDYIDLFLVHWPIAAEKNADRTVKIGPDGKYVINKALTENPEPTWRAMEELVDSGIV 171 Query: 574 KSIGVSNFNSKQLERLLQHATVKPVVNQVECHPYLNQKRLKEFCEARGVKITXYSPLGSP 753 K+IGVSN+ L++LL+ A +KP VNQ+E HP+L L EFC + YSPLGS Sbjct: 172 KAIGVSNWTIPGLKQLLEFARIKPAVNQIEIHPFLPNTELVEFCFQNDILPEAYSPLGSQ 231 Query: 754 DR 759 ++ Sbjct: 232 NQ 233 Score = 64.5 bits (150), Expect = 4e-09 Identities = 34/84 (40%), Positives = 47/84 (55%), Gaps = 3/84 (3%) Frame = +3 Query: 138 GASXPVFGXGXWXSK--PGXVXXAVKXAIDIGXRHIDCAYVYGNXXXVGXAITSKI-KEG 308 GA P G G + ++ G AV A+D+G RH+DCA+ Y N VG AI + + Sbjct: 20 GAKIPAVGFGTFANEGAKGETYAAVTKALDVGYRHLDCAWFYLNEDEVGDAIRDFLARRP 79 Query: 309 VVTRXXLFITSKLWNTFHRPDLVR 380 VTR LFI +K+WN H P+ V+ Sbjct: 80 DVTRKDLFICTKVWNHLHEPEDVK 103 Score = 33.5 bits (73), Expect = 7.5 Identities = 13/34 (38%), Positives = 23/34 (67%) Frame = +2 Query: 794 EDPKLKXIADRLGKTVAQVLIRYQIDXGXIVXPE 895 ++P L +ADR G ++AQVL+ + + G +V P+ Sbjct: 243 DNPTLNAVADRRGSSLAQVLLAWGLKRGYVVLPK 276 >UniRef50_P22045 Cluster: Probable reductase; n=101; cellular organisms|Rep: Probable reductase - Leishmania major Length = 284 Score = 99 bits (238), Expect = 8e-20 Identities = 54/113 (47%), Positives = 72/113 (63%) Frame = +1 Query: 409 LNVQYLDLYLIHWPQAYKEDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGV 588 L V Y+DLYLIHWP+ K+ S + GK Y+D+W+A E L KE V++IGV Sbjct: 101 LGVDYIDLYLIHWPRG-KDILS-----KEGK------KYLDSWRAFEQLYKEKKVRAIGV 148 Query: 589 SNFNSKQLERLLQHATVKPVVNQVECHPYLNQKRLKEFCEARGVKITXYSPLG 747 SNF+ LE +L TV P+VNQVE HP NQ L+ FC+A+ +K+ +SPLG Sbjct: 149 SNFHIHHLEDVLAMCTVTPMVNQVELHPLNNQADLRAFCDAKQIKVEAWSPLG 201 Score = 57.2 bits (132), Expect = 5e-07 Identities = 35/93 (37%), Positives = 44/93 (47%), Gaps = 1/93 (1%) Frame = +3 Query: 120 VVXFXXGASXPVFGXGXWXSKPGXVXX-AVKXAIDIGXRHIDCAYVYGNXXXVGXAITSK 296 +V G P FG G W S G V AV A+ G RHID A +Y N VG + Sbjct: 8 MVTLSNGVKMPQFGLGVWQSPAGEVTENAVNWALCAGYRHIDTAAIYKNEESVGAGL--- 64 Query: 297 IKEGVVTRXXLFITSKLWNTFHRPDLVRGALQE 395 + V R +FIT+KLWNT + A +E Sbjct: 65 -RASGVPREDVFITTKLWNTEQGYESTLAAFEE 96 >UniRef50_UPI00015B5BD7 Cluster: PREDICTED: similar to aldo-keto reductase; n=1; Nasonia vitripennis|Rep: PREDICTED: similar to aldo-keto reductase - Nasonia vitripennis Length = 310 Score = 99.5 bits (237), Expect = 1e-19 Identities = 53/117 (45%), Positives = 72/117 (61%), Gaps = 1/117 (0%) Frame = +1 Query: 409 LNVQYLDLYLIHWPQAYKEDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGV 588 L+ YLDLYLIHWP A + L + + K++ V TW + L ++GL++SIGV Sbjct: 123 LDTSYLDLYLIHWPGASR---ILENSPDNPKLR------VTTWATLVELQQKGLLRSIGV 173 Query: 589 SNFNSKQLERLLQHAT-VKPVVNQVECHPYLNQKRLKEFCEARGVKITXYSPLGSPD 756 SN+ LE LL+H + VKP VNQVECHP+ Q L EFC +G+ + YS LG+ D Sbjct: 174 SNYTVGHLEHLLEHCSGVKPDVNQVECHPHFRQDELIEFCTKQGIHVQAYSSLGTSD 230 Score = 44.0 bits (99), Expect = 0.005 Identities = 31/110 (28%), Positives = 52/110 (47%), Gaps = 2/110 (1%) Frame = +3 Query: 102 MAPXIPVVXFXXGASXPVFGXGXWXSKPGXVXXAV-KXAIDIGXRHIDCAYVYGNXXXVG 278 + P I + G P+ G G + + V V + +G R ID A VY N +G Sbjct: 19 LTPTIRDLRLNNGYDMPLVGIGTYKVRGREVIKRVIDESFAVGFRSIDTAVVYRNEEDIG 78 Query: 279 XAITSKIKEGVVTRXXLFITSKLWNTFH-RPDLVRGALQEXLXQSERSVL 425 A+ + + + R +FITSKL + + PD +R ++++ L + S L Sbjct: 79 LALKELLPKYNLKREDIFITSKLSPSDNGDPDKIRKSVEDSLKALDTSYL 128 >UniRef50_A2FPE2 Cluster: Oxidoreductase, aldo/keto reductase family protein; n=3; Trichomonas vaginalis G3|Rep: Oxidoreductase, aldo/keto reductase family protein - Trichomonas vaginalis G3 Length = 309 Score = 99.5 bits (237), Expect = 1e-19 Identities = 51/117 (43%), Positives = 72/117 (61%), Gaps = 4/117 (3%) Frame = +1 Query: 409 LNVQYLDLYLIHWPQAY--KEDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSI 582 L ++YLDL L+HW A+ +ED P D++GKI ++D ++TWKAME GL K I Sbjct: 93 LKLEYLDLVLVHWACAFQSREDDEYLPRDETGKIITENIDILETWKAMEECYNLGLAKHI 152 Query: 583 GVSNFNSKQLERLLQHATVK--PVVNQVECHPYLNQKRLKEFCEARGVKITXYSPLG 747 GVSNF+ +QLER+ VK P NQVE H YL Q+ + ++ R + + Y+ LG Sbjct: 153 GVSNFSIEQLERMRYDPGVKIQPYCNQVESHMYLQQQPMLDYLTQRKMYMISYTCLG 209 Score = 67.7 bits (158), Expect = 4e-10 Identities = 40/108 (37%), Positives = 58/108 (53%), Gaps = 2/108 (1%) Frame = +3 Query: 150 PVFGXGXWXSK-PGXVXXAVKXAI-DIGXRHIDCAYVYGNXXXVGXAITSKIKEGVVTRX 323 P G G + ++ P + AV AI D G RH+DCA Y N +G A++ +G V R Sbjct: 5 PSIGLGTFLAEDPAALKAAVHSAIEDSGYRHVDCAAYYKNQEIIGEALSEIFAKGQVKRE 64 Query: 324 XLFITSKLWNTFHRPDLVRGALQEXLXQSERSVLGSVPDTLAPGLQGR 467 ++ITSK+WNT HRPDL+ +++ L + + L V A Q R Sbjct: 65 EVWITSKVWNTKHRPDLLVKDVKKTLKELKLEYLDLVLVHWACAFQSR 112 >UniRef50_A1D4E3 Cluster: D-xylose reductase (Xyl1), putative; n=5; Pezizomycotina|Rep: D-xylose reductase (Xyl1), putative - Neosartorya fischeri (strain ATCC 1020 / DSM 3700 / NRRL 181)(Aspergillus fischerianus (strain ATCC 1020 / DSM 3700 / NRRL 181)) Length = 321 Score = 99.5 bits (237), Expect = 1e-19 Identities = 47/125 (37%), Positives = 76/125 (60%), Gaps = 5/125 (4%) Frame = +1 Query: 388 CRXPWXNLNVQYLDLYLIHWPQA--YKEDGSLFPT---DQSGKIQFSDVDYVDTWKAMEP 552 CR + + Y DL+++H+P A Y + +P ++ K++FS+ +TW AME Sbjct: 94 CRKQLADWGLDYFDLFIVHFPIALKYVDPAVRYPPGWLSENNKLEFSNASIQETWTAMES 153 Query: 553 LVKEGLVKSIGVSNFNSKQLERLLQHATVKPVVNQVECHPYLNQKRLKEFCEARGVKITX 732 LV + L +SIGVSNF+++ L LL++A ++P Q+E HPYL Q+RL + + G+ +T Sbjct: 154 LVDKKLARSIGVSNFSAQLLMDLLRYARIRPATLQIEHHPYLTQERLVTYAQKEGIAVTA 213 Query: 733 YSPLG 747 YS G Sbjct: 214 YSSFG 218 Score = 63.3 bits (147), Expect = 8e-09 Identities = 34/95 (35%), Positives = 42/95 (44%) Frame = +3 Query: 117 PVVXFXXGASXPVFGXGXWXSKPGXVXXAVKXAIDIGXRHIDCAYVYGNXXXVGXAITSK 296 P G P+ G G W + AI G R D A YGN G + Sbjct: 4 PSTKLNSGYDMPLVGFGLWKVNNETCADQIYHAIKAGYRLFDGACDYGNEVEAGKGVARA 63 Query: 297 IKEGVVTRXXLFITSKLWNTFHRPDLVRGALQEXL 401 I+EG+V R LFI SKLWN+FH D V ++ L Sbjct: 64 IQEGIVKREDLFIVSKLWNSFHDGDRVEPICRKQL 98 >UniRef50_P14065 Cluster: Protein GCY; n=13; Saccharomycetales|Rep: Protein GCY - Saccharomyces cerevisiae (Baker's yeast) Length = 312 Score = 99.5 bits (237), Expect = 1e-19 Identities = 53/128 (41%), Positives = 75/128 (58%), Gaps = 10/128 (7%) Frame = +1 Query: 409 LNVQYLDLYLIHWPQ----AY--KEDGSLFPTDQSGK--IQFSDVDYVDTWKAMEPLVKE 564 L + Y+DLYL+HWP AY ED PT + G + ++ +++ TW+ M+ L K Sbjct: 101 LGLDYVDLYLMHWPARLDPAYIKNEDILSVPTKKDGSRAVDITNWNFIKTWELMQELPKT 160 Query: 565 GLVKSIGVSNFNSKQLERLL--QHATVKPVVNQVECHPYLNQKRLKEFCEARGVKITXYS 738 G K++GVSNF+ L+ LL Q + P NQVE HP L Q L FC+++G+ + YS Sbjct: 161 GKTKAVGVSNFSINNLKDLLASQGNKLTPAANQVEIHPLLPQDELINFCKSKGIVVEAYS 220 Query: 739 PLGSPDRP 762 PLGS D P Sbjct: 221 PLGSTDAP 228 Score = 61.3 bits (142), Expect = 3e-08 Identities = 34/86 (39%), Positives = 44/86 (51%), Gaps = 1/86 (1%) Frame = +3 Query: 120 VVXFXXGASXPVFGXGXWXSKPGXVXXAVKXAIDIGXRHIDCAYVYGNXXXVGXAITSKI 299 ++ GA P G G W SK AV A+ G RHID A +Y N VG A I Sbjct: 11 ILSLNTGAQIPQIGLGTWQSKENDAYKAVLTALKDGYRHIDTAAIYRNEDQVGQA----I 66 Query: 300 KEGVVTRXXLFITSKLWNT-FHRPDL 374 K+ V R +F+T+KLW T H P++ Sbjct: 67 KDSGVPREEIFVTTKLWCTQHHEPEV 92 >UniRef50_A6ESC0 Cluster: ARA1; n=1; unidentified eubacterium SCB49|Rep: ARA1 - unidentified eubacterium SCB49 Length = 280 Score = 98.7 bits (235), Expect = 2e-19 Identities = 52/117 (44%), Positives = 71/117 (60%) Frame = +1 Query: 406 NLNVQYLDLYLIHWPQAYKEDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIG 585 +L + YLDLYLIHWP A + ++ K Q ++ DTW AME L K+G +K++G Sbjct: 96 DLQLDYLDLYLIHWPAAAHQF-------ENWK-QLNN----DTWSAMEKLYKDGKIKALG 143 Query: 586 VSNFNSKQLERLLQHATVKPVVNQVECHPYLNQKRLKEFCEARGVKITXYSPLGSPD 756 VSNF L LLQHAT+KP VNQ+E HP Q+ +FC +++ +SPLG D Sbjct: 144 VSNFMEHHLTPLLQHATIKPTVNQIEYHPGYMQQDCVQFCNDNNIQVEGWSPLGRGD 200 Score = 57.6 bits (133), Expect = 4e-07 Identities = 30/69 (43%), Positives = 37/69 (53%), Gaps = 1/69 (1%) Frame = +3 Query: 150 PVFGXGXWXSKPGXVXX-AVKXAIDIGXRHIDCAYVYGNXXXVGXAITSKIKEGVVTRXX 326 P G G W + G A+K AID G +HID A +Y N VG IKE + R Sbjct: 14 PAIGFGTWQTPDGQTAINAIKTAIDAGYKHIDAAAIYKNEKGVGLG----IKEANIDRKD 69 Query: 327 LFITSKLWN 353 LF+TSK+WN Sbjct: 70 LFVTSKVWN 78 >UniRef50_Q3E9M9 Cluster: Uncharacterized protein At5g01670.2; n=7; Magnoliophyta|Rep: Uncharacterized protein At5g01670.2 - Arabidopsis thaliana (Mouse-ear cress) Length = 349 Score = 97.1 bits (231), Expect = 5e-19 Identities = 50/116 (43%), Positives = 69/116 (59%) Frame = +1 Query: 409 LNVQYLDLYLIHWPQAYKEDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGV 588 L ++YLDLYLIHWP +E S P ++G + D D W+ ME L K+ LV++IGV Sbjct: 137 LQLEYLDLYLIHWPIRLREGASKPP--KAGDVL--DFDMEGVWREMENLSKDSLVRNIGV 192 Query: 589 SNFNSKQLERLLQHATVKPVVNQVECHPYLNQKRLKEFCEARGVKITXYSPLGSPD 756 NF +L +LL A + P V Q+E HP R+ EFC+ + +T YSPLGS + Sbjct: 193 CNFTVTKLNKLLGFAELIPAVCQMEMHPGWRNDRILEFCKKNEIHVTAYSPLGSQE 248 Score = 52.8 bits (121), Expect = 1e-05 Identities = 28/73 (38%), Positives = 35/73 (47%) Frame = +3 Query: 138 GASXPVFGXGXWXSKPGXVXXAVKXAIDIGXRHIDCAYVYGNXXXVGXAITSKIKEGVVT 317 G P G G W S V ++ G RHID A+ YG+ VG I + G + Sbjct: 21 GHKIPAVGLGTWRSGSQAAHAVVTAIVEGGYRHIDTAWEYGDQREVGQGIKRAMHAG-LE 79 Query: 318 RXXLFITSKLWNT 356 R LF+TSKLW T Sbjct: 80 RRDLFVTSKLWYT 92 >UniRef50_UPI00015B40FA Cluster: PREDICTED: similar to CG2767-PA; n=2; Nasonia vitripennis|Rep: PREDICTED: similar to CG2767-PA - Nasonia vitripennis Length = 356 Score = 96.7 bits (230), Expect = 7e-19 Identities = 47/118 (39%), Positives = 72/118 (61%), Gaps = 3/118 (2%) Frame = +1 Query: 409 LNVQYLDLYLIHWPQAYKEDGSLFPT--DQSGKIQF-SDVDYVDTWKAMEPLVKEGLVKS 579 L ++Y+++YLIH P A+ +D + + G + +D D+V W+AME VK G V+S Sbjct: 122 LGLEYVNMYLIHKPFAFVKDKYKYEPALNPDGSVVLDTDTDHVAIWRAMEKQVKAGRVRS 181 Query: 580 IGVSNFNSKQLERLLQHATVKPVVNQVECHPYLNQKRLKEFCEARGVKITXYSPLGSP 753 IG+SNFN QL + +HA +KP Q+E Y Q+ ++E C R + +T +S LGSP Sbjct: 182 IGLSNFNKSQLLNVYEHAEIKPSNLQIELQAYNQQRPMRELCAERNITVTAFSTLGSP 239 Score = 54.4 bits (125), Expect = 4e-06 Identities = 27/70 (38%), Positives = 36/70 (51%) Frame = +3 Query: 138 GASXPVFGXGXWXSKPGXVXXAVKXAIDIGXRHIDCAYVYGNXXXVGXAITSKIKEGVVT 317 G P+ G G W P + AV A++ G RHID A+ YGN +G + +G Sbjct: 33 GHDMPMIGLGTWQMPPEAIEVAVTAALESGYRHIDTAFTYGNEEAIGKTLKKWFDKG-GK 91 Query: 318 RXXLFITSKL 347 R LFIT+KL Sbjct: 92 REDLFITTKL 101 >UniRef50_Q41E86 Cluster: 2,5-didehydrogluconate reductase; n=2; Bacteria|Rep: 2,5-didehydrogluconate reductase - Exiguobacterium sibiricum 255-15 Length = 274 Score = 96.7 bits (230), Expect = 7e-19 Identities = 48/112 (42%), Positives = 68/112 (60%) Frame = +1 Query: 409 LNVQYLDLYLIHWPQAYKEDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGV 588 L V Y+DLYLIHWP D L Y+DTW+A+E L ++G K+IGV Sbjct: 95 LGVDYVDLYLIHWPMP---DEDL---------------YMDTWRALEQLYRDGKAKAIGV 136 Query: 589 SNFNSKQLERLLQHATVKPVVNQVECHPYLNQKRLKEFCEARGVKITXYSPL 744 SNF+ L R+L+ TV P VNQ+E HP+L+Q+ ++ FC+ G+ + +SPL Sbjct: 137 SNFHIPHLTRVLEEGTVVPAVNQIELHPFLSQEAIRAFCQKNGIVVEAWSPL 188 Score = 47.2 bits (107), Expect = 6e-04 Identities = 26/77 (33%), Positives = 38/77 (49%) Frame = +3 Query: 123 VXFXXGASXPVFGXGXWXSKPGXVXXAVKXAIDIGXRHIDCAYVYGNXXXVGXAITSKIK 302 V G P G G + V AV+ A+ +G R ID A +Y N VG A+ K Sbjct: 4 VTLNNGLVMPQLGYGVFKVPEQEVYEAVREALRVGYRSIDTAMIYENEAGVGRAL----K 59 Query: 303 EGVVTRXXLFITSKLWN 353 + + R +F+T+K+WN Sbjct: 60 DSGIPREDIFLTTKVWN 76 >UniRef50_A6SI80 Cluster: Putative uncharacterized protein; n=1; Botryotinia fuckeliana B05.10|Rep: Putative uncharacterized protein - Botryotinia fuckeliana B05.10 Length = 253 Score = 96.7 bits (230), Expect = 7e-19 Identities = 48/114 (42%), Positives = 69/114 (60%), Gaps = 7/114 (6%) Frame = +1 Query: 415 VQYLDLYLIHWPQA--YKEDGSLFP-----TDQSGKIQFSDVDYVDTWKAMEPLVKEGLV 573 + Y DL+++H+P A Y + +P +D+ G +Q S +TW+AME LV EGL Sbjct: 79 IDYFDLFIVHFPVALRYVDPAVRYPPGWQYSDKEGDVQQSKASIQETWQAMEKLVDEGLA 138 Query: 574 KSIGVSNFNSKQLERLLQHATVKPVVNQVECHPYLNQKRLKEFCEARGVKITXY 735 KSIGVSNF L LL++A ++P Q+E HPYL Q L + E+ G+K+T Y Sbjct: 139 KSIGVSNFQGALLIDLLRYARIRPATLQIEHHPYLVQNTLLKLAESEGIKVTAY 192 >UniRef50_Q6C2L0 Cluster: Yarrowia lipolytica chromosome F of strain CLIB122 of Yarrowia lipolytica; n=3; Yarrowia lipolytica|Rep: Yarrowia lipolytica chromosome F of strain CLIB122 of Yarrowia lipolytica - Yarrowia lipolytica (Candida lipolytica) Length = 324 Score = 96.3 bits (229), Expect = 9e-19 Identities = 49/121 (40%), Positives = 72/121 (59%), Gaps = 6/121 (4%) Frame = +1 Query: 406 NLNVQYLDLYLIHWPQAYKEDG----SLFPTDQSGKIQFSDV--DYVDTWKAMEPLVKEG 567 +L++ Y+DL L+HWP + D +++ + G +++SD D++ T+K +E G Sbjct: 97 DLSLDYVDLLLVHWPVSLLADSDDPRAIYLVNTDGSVRYSDSLDDWITTYKQIEEEKLSG 156 Query: 568 LVKSIGVSNFNSKQLERLLQHATVKPVVNQVECHPYLNQKRLKEFCEARGVKITXYSPLG 747 KSIGVSN + L+RLL P VNQ E HPYL QK+ EF E G+ +T +SPLG Sbjct: 157 RTKSIGVSNVSEVYLKRLLDQVKTVPAVNQFEIHPYLPQKKEIEFNEKHGILVTAFSPLG 216 Query: 748 S 750 S Sbjct: 217 S 217 Score = 60.9 bits (141), Expect = 4e-08 Identities = 32/75 (42%), Positives = 41/75 (54%) Frame = +3 Query: 138 GASXPVFGXGXWXSKPGXVXXAVKXAIDIGXRHIDCAYVYGNXXXVGXAITSKIKEGVVT 317 G S P G G + G V V AI G RHID A++YG+ VG I I E +V Sbjct: 12 GHSIPALGLGT--ASDGNVEEVVYAAIKNGYRHIDTAFIYGSEVDVGKGIKRAIDEELVK 69 Query: 318 RXXLFITSKLWNTFH 362 R LF+T+K+W TF+ Sbjct: 70 RENLFVTTKVWPTFY 84 >UniRef50_A2QVE5 Cluster: Similarity: shows similarity to several dehydrogenases of different specificities; n=4; Pezizomycotina|Rep: Similarity: shows similarity to several dehydrogenases of different specificities - Aspergillus niger Length = 381 Score = 96.3 bits (229), Expect = 9e-19 Identities = 47/120 (39%), Positives = 66/120 (55%), Gaps = 6/120 (5%) Frame = +1 Query: 409 LNVQYLDLYLIHWPQAYKEDGSLFPTDQSGKIQFSDV------DYVDTWKAMEPLVKEGL 570 L + YLDLYL+HWP ++ LFP + ++ DV VDTWKAM L K Sbjct: 103 LELDYLDLYLVHWPVSFTTGSELFPLVKDSSVEGGDVVINDDISIVDTWKAMTQLPKSK- 161 Query: 571 VKSIGVSNFNSKQLERLLQHATVKPVVNQVECHPYLNQKRLKEFCEARGVKITXYSPLGS 750 +++GVSN LE ++ V P VNQ+E HP L L E+C+ +G+ +T YS G+ Sbjct: 162 ARTVGVSNHMIPHLEAIINATGVVPAVNQIERHPVLQSNELIEYCQKKGIHVTAYSAFGN 221 Score = 74.9 bits (176), Expect = 2e-12 Identities = 42/102 (41%), Positives = 51/102 (50%), Gaps = 1/102 (0%) Frame = +3 Query: 123 VXFXXGASXPVFGXGXWXSKPGXVXXAVKXAIDIGXRHIDCAYVYGNXXXVGXAITSKIK 302 V GA P G G W S PG V AV A+ G RH+D A +Y N V I K Sbjct: 7 VTLNSGAQIPQLGFGTWQSAPGQVGDAVYEALKAGYRHLDLATIYQNQREVAEGIKRAYK 66 Query: 303 E-GVVTRXXLFITSKLWNTFHRPDLVRGALQEXLXQSERSVL 425 + + R +FITSKLWN+ H P +V AL E L + E L Sbjct: 67 DVPGLKREDIFITSKLWNSQHDPAVVEKALDECLAELELDYL 108 >UniRef50_Q7PM68 Cluster: ENSANGP00000014386; n=1; Anopheles gambiae str. PEST|Rep: ENSANGP00000014386 - Anopheles gambiae str. PEST Length = 310 Score = 95.9 bits (228), Expect = 1e-18 Identities = 45/131 (34%), Positives = 69/131 (52%) Frame = +1 Query: 388 CRXPWXNLNVQYLDLYLIHWPQAYKEDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEG 567 CR L + Y+DLYL+H P A + + + + W +E +EG Sbjct: 98 CRMTLDRLGMDYVDLYLMHTPVALQSEKKCARNGTKLNAIDDSIAPTEAWIGLEQCYQEG 157 Query: 568 LVKSIGVSNFNSKQLERLLQHATVKPVVNQVECHPYLNQKRLKEFCEARGVKITXYSPLG 747 L +SIGVSNFN Q+ LL A++ P VNQ+EC NQ+ +++FC+ + + + Y+PLG Sbjct: 158 LCRSIGVSNFNEHQINALLSDASIVPAVNQIECSIGFNQRPMRKFCQQQNILVMGYTPLG 217 Query: 748 SPDRPWGQARR 780 P+ Q R Sbjct: 218 KQKLPFLQNNR 228 Score = 60.1 bits (139), Expect = 8e-08 Identities = 33/77 (42%), Positives = 41/77 (53%), Gaps = 1/77 (1%) Frame = +3 Query: 150 PVFGXGXWXSKPGXVXXAVKXAIDIGXRHIDCAYVYGNXXXVGXAITSKIKE-GVVTRXX 326 P G G + A++ AID+G R D A YGN VG AI KI+E +TR Sbjct: 18 PTIGLGTYSILGADGKEAIRTAIDVGYRMFDTAVAYGNEAIVGEAIREKIRECNNLTRDD 77 Query: 327 LFITSKLWNTFHRPDLV 377 FI SKL ++HR DLV Sbjct: 78 FFIISKLSGSYHRQDLV 94 >UniRef50_Q03TW0 Cluster: Aldo/keto reductase of diketogulonate reductase family; n=1; Lactobacillus brevis ATCC 367|Rep: Aldo/keto reductase of diketogulonate reductase family - Lactobacillus brevis (strain ATCC 367 / JCM 1170) Length = 293 Score = 95.5 bits (227), Expect = 2e-18 Identities = 49/113 (43%), Positives = 65/113 (57%) Frame = +1 Query: 409 LNVQYLDLYLIHWPQAYKEDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGV 588 L + YLDLYLIHWP Y+D+W+AME L K G +K+IGV Sbjct: 106 LGLDYLDLYLIHWPAP---------------------GYLDSWRAMEDLYKAGKIKNIGV 144 Query: 589 SNFNSKQLERLLQHATVKPVVNQVECHPYLNQKRLKEFCEARGVKITXYSPLG 747 SNFN Q+ +L H TVKPVV+Q+E HPY Q + + E++G+ +SPLG Sbjct: 145 SNFNQTQMADILAHGTVKPVVDQIETHPYFQQNDMHAYLESQGILHEAWSPLG 197 Score = 59.3 bits (137), Expect = 1e-07 Identities = 37/97 (38%), Positives = 46/97 (47%), Gaps = 1/97 (1%) Frame = +3 Query: 114 IPVVXFXXGASXPVFGXGXWX-SKPGXVXXAVKXAIDIGXRHIDCAYVYGNXXXVGXAIT 290 IP + G P G G + A+K A+ G RHID A YGN VG AI Sbjct: 11 IPDLPMNNGHQIPQLGLGVFQVDNAEDTKNAIKWALAAGYRHIDTAAYYGNEQWVGEAI- 69 Query: 291 SKIKEGVVTRXXLFITSKLWNTFHRPDLVRGALQEXL 401 +E V R +F+TSKLWN+ D + A QE L Sbjct: 70 ---RESDVPRDQIFVTSKLWNSVRGYDETQAAFQETL 103 >UniRef50_P38715 Cluster: NADPH-dependent aldose reductase GRE3; n=39; cellular organisms|Rep: NADPH-dependent aldose reductase GRE3 - Saccharomyces cerevisiae (Baker's yeast) Length = 327 Score = 95.5 bits (227), Expect = 2e-18 Identities = 50/124 (40%), Positives = 72/124 (58%), Gaps = 10/124 (8%) Frame = +1 Query: 406 NLNVQYLDLYLIHWPQAYK--------EDGSLFPTD--QSGKIQFSDVDYVDTWKAMEPL 555 ++ + YLDLY IH+P A+K G D + G I + V +DT++A+E Sbjct: 99 DMGLDYLDLYYIHFPIAFKYVPFEEKYPPGFYTGADDEKKGHITEAHVPIIDTYRALEEC 158 Query: 556 VKEGLVKSIGVSNFNSKQLERLLQHATVKPVVNQVECHPYLNQKRLKEFCEARGVKITXY 735 V EGL+KSIGVSNF ++ LL+ +KPV Q+E HPYL Q+ L EFC+ +++ Y Sbjct: 159 VDEGLIKSIGVSNFQGSLIQDLLRGCRIKPVALQIEHHPYLTQEHLVEFCKLHDIQVVAY 218 Query: 736 SPLG 747 S G Sbjct: 219 SSFG 222 Score = 72.9 bits (171), Expect = 1e-11 Identities = 37/94 (39%), Positives = 48/94 (51%) Frame = +3 Query: 120 VVXFXXGASXPVFGXGXWXSKPGXVXXAVKXAIDIGXRHIDCAYVYGNXXXVGXAITSKI 299 +V G P+ G G W + AI +G R D A YGN VG I I Sbjct: 4 LVTLNNGLKMPLVGLGCWKIDKKVCANQIYEAIKLGYRLFDGACDYGNEKEVGEGIRKAI 63 Query: 300 KEGVVTRXXLFITSKLWNTFHRPDLVRGALQEXL 401 EG+V+R +F+ SKLWN FH PD V+ AL++ L Sbjct: 64 SEGLVSRKDIFVVSKLWNNFHHPDHVKLALKKTL 97 >UniRef50_Q838E0 Cluster: Oxidoreductase, aldo/keto reductase family; n=24; Bacilli|Rep: Oxidoreductase, aldo/keto reductase family - Enterococcus faecalis (Streptococcus faecalis) Length = 279 Score = 95.1 bits (226), Expect = 2e-18 Identities = 50/112 (44%), Positives = 66/112 (58%) Frame = +1 Query: 409 LNVQYLDLYLIHWPQAYKEDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGV 588 L + YLDLYLIHWP + Y ++W+A+E L EG VK+IGV Sbjct: 104 LGLDYLDLYLIHWP--------------------GNNSYKESWQALETLYAEGKVKAIGV 143 Query: 589 SNFNSKQLERLLQHATVKPVVNQVECHPYLNQKRLKEFCEARGVKITXYSPL 744 SNF LE LL +A V PV+NQVE HP L+QK +++FCE +K+ +SPL Sbjct: 144 SNFQVHHLEDLLSYAKVVPVINQVELHPKLDQKEVRDFCEKHDIKVQAWSPL 195 Score = 45.2 bits (102), Expect = 0.002 Identities = 25/77 (32%), Positives = 33/77 (42%) Frame = +3 Query: 123 VXFXXGASXPVFGXGXWXSKPGXVXXAVKXAIDIGXRHIDCAYVYGNXXXVGXAITSKIK 302 V G P G G + V+ I G R ID A +YGN G I + + Sbjct: 9 VTLNNGTKIPGMGLGVFQIPDEETAKVVEEGIINGYRLIDTAQIYGNESGTGAGIKAGLA 68 Query: 303 EGVVTRXXLFITSKLWN 353 + R LF+TSK+WN Sbjct: 69 ATGLNREDLFVTSKVWN 85 >UniRef50_Q1YPE5 Cluster: Aldehyde reductase; n=7; Bacteria|Rep: Aldehyde reductase - gamma proteobacterium HTCC2207 Length = 330 Score = 95.1 bits (226), Expect = 2e-18 Identities = 50/130 (38%), Positives = 76/130 (58%), Gaps = 9/130 (6%) Frame = +1 Query: 388 CRXPWXNLNVQYLDLYLIHWPQA--YKEDGSLFPT----DQSGKIQFSDVDYV---DTWK 540 CR +L + Y+DLYL+H+P A Y + +P D S + ++D V +TW Sbjct: 97 CRRSMDDLGLDYIDLYLVHFPIALRYVDFNDRYPAEWIFDHSAEDPAMELDQVPLSETWG 156 Query: 541 AMEPLVKEGLVKSIGVSNFNSKQLERLLQHATVKPVVNQVECHPYLNQKRLKEFCEARGV 720 AME LV+ GLV+ IGV N+++ L L+ +A +KP + Q+E HPYL Q+ L + + Sbjct: 157 AMEQLVESGLVRQIGVCNYSAVLLHDLMSYARIKPAMLQIESHPYLTQEALLRTARSYNM 216 Query: 721 KITXYSPLGS 750 +T +SPLGS Sbjct: 217 AVTAFSPLGS 226 Score = 74.1 bits (174), Expect = 4e-12 Identities = 36/86 (41%), Positives = 46/86 (53%) Frame = +3 Query: 144 SXPVFGXGXWXSKPGXVXXAVKXAIDIGXRHIDCAYVYGNXXXVGXAITSKIKEGVVTRX 323 S P G G W AV AI +G RH+D A YGN VG I I EG+ +R Sbjct: 16 SMPAVGLGLWKITQDSAAQAVYEAIKVGYRHLDSAADYGNEQQVGEGIARAIAEGLCSRE 75 Query: 324 XLFITSKLWNTFHRPDLVRGALQEXL 401 L+IT+KLWNT+HR + V A + + Sbjct: 76 ELWITTKLWNTYHRAEHVEAACRRSM 101 >UniRef50_Q9HGY0 Cluster: Glycerol dehydrogenase; n=8; Saccharomycetaceae|Rep: Glycerol dehydrogenase - Zygosaccharomyces rouxii (Candida mogii) Length = 310 Score = 94.7 bits (225), Expect = 3e-18 Identities = 52/128 (40%), Positives = 74/128 (57%), Gaps = 10/128 (7%) Frame = +1 Query: 409 LNVQYLDLYLIHWPQAYK----EDGSLFPTDQSGKIQFSDVD----YVDTWKAMEPLVKE 564 L + Y+ LYL+HWP + +DG+LF + DVD ++ TW+ M+ L++ Sbjct: 100 LGLDYVGLYLVHWPVPLRTENIKDGNLFQFAEKPDGS-KDVDLEWNFIKTWELMQKLLES 158 Query: 565 GLVKSIGVSNFNSKQLERLLQHATVK--PVVNQVECHPYLNQKRLKEFCEARGVKITXYS 738 G K+IGVSNF+ L+ LL T K P VNQVE HP L Q+ L ++C +G+ I YS Sbjct: 159 GKTKAIGVSNFSVNNLKDLLAAPTTKVTPAVNQVEFHPLLPQEELIQYCSEKGIVIEAYS 218 Query: 739 PLGSPDRP 762 PLG + P Sbjct: 219 PLGGENAP 226 Score = 58.0 bits (134), Expect = 3e-07 Identities = 33/76 (43%), Positives = 40/76 (52%) Frame = +3 Query: 138 GASXPVFGXGXWXSKPGXVXXAVKXAIDIGXRHIDCAYVYGNXXXVGXAITSKIKEGVVT 317 G + P G G W SK AV A+ G RHID A VYGN VG A I++ V Sbjct: 16 GQTIPQVGLGTWRSKENEGYKAVIEALKAGYRHIDGAAVYGNEGEVGKA----IQDSGVP 71 Query: 318 RXXLFITSKLWNTFHR 365 R +F+T+KLW T R Sbjct: 72 RNEIFLTTKLWCTHQR 87 >UniRef50_Q0DHN0 Cluster: Os05g0456200 protein; n=2; Oryza sativa (japonica cultivar-group)|Rep: Os05g0456200 protein - Oryza sativa subsp. japonica (Rice) Length = 229 Score = 94.3 bits (224), Expect = 4e-18 Identities = 42/81 (51%), Positives = 56/81 (69%) Frame = +1 Query: 520 DYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQHATVKPVVNQVECHPYLNQKRLKE 699 D TW+AME L G ++IGVSNF+ K+LE LL A V P VNQVECHP Q +L++ Sbjct: 76 DIPATWQAMEKLYDSGKARAIGVSNFSCKKLEDLLNVARVPPAVNQVECHPVWQQGKLRK 135 Query: 700 FCEARGVKITXYSPLGSPDRP 762 C+++GV ++ Y+PLGSP P Sbjct: 136 LCQSKGVHLSAYAPLGSPGSP 156 Score = 50.4 bits (115), Expect = 6e-05 Identities = 21/52 (40%), Positives = 29/52 (55%) Frame = +3 Query: 141 ASXPVFGXGXWXSKPGXVXXAVKXAIDIGXRHIDCAYVYGNXXXVGXAITSK 296 A+ P G G W PG V A++ A+ +G RHIDC+ YGN V + +K Sbjct: 11 AAIPSVGLGTWQISPGAVQDAIRAAVQVGYRHIDCSPQYGNQKEVHGPVRAK 62 >UniRef50_Q01HB5 Cluster: OSIGBa0136O08-OSIGBa0153H12.9 protein; n=4; Oryza sativa|Rep: OSIGBa0136O08-OSIGBa0153H12.9 protein - Oryza sativa (Rice) Length = 337 Score = 94.3 bits (224), Expect = 4e-18 Identities = 54/124 (43%), Positives = 73/124 (58%), Gaps = 4/124 (3%) Frame = +1 Query: 409 LNVQYLDLYLIHWPQAY-KED--GSLFPTDQS-GKIQFSDVDYVDTWKAMEPLVKEGLVK 576 L + Y+DL+LIHWP A K+D G L D S G + F D W+ ME + GL + Sbjct: 120 LGLDYVDLFLIHWPVAIGKKDAAGELTWDDLSRGLVPF---DMEGVWRGMEECHRLGLAR 176 Query: 577 SIGVSNFNSKQLERLLQHATVKPVVNQVECHPYLNQKRLKEFCEARGVKITXYSPLGSPD 756 SIGVSNF++ ++ RLL A V P VNQVE + Q++++E C GV + YSPLG+ Sbjct: 177 SIGVSNFSAAKMSRLLALAAVPPAVNQVEMNVGWRQEKVREVCGEGGVVVAAYSPLGAHG 236 Query: 757 RPWG 768 WG Sbjct: 237 AHWG 240 Score = 60.1 bits (139), Expect = 8e-08 Identities = 36/101 (35%), Positives = 50/101 (49%), Gaps = 2/101 (1%) Frame = +3 Query: 105 APXIPVVXFXXGASXPVFGXGXWXSKP-GXVXXAVKXAIDIGXRHIDCAYVYGNXXXVGX 281 A +P V G + PV G G S P + + A+ +G RH+D A VYG VG Sbjct: 17 ATAVPCVTLNSGHAMPVLGFGTGSSTPPADLAATIAHAVRLGYRHLDTAAVYGTEGAVGA 76 Query: 282 AITSKIKEG-VVTRXXLFITSKLWNTFHRPDLVRGALQEXL 401 A+ ++ G V +R LF+T+KL P V AL+E L Sbjct: 77 AVAEAVRCGAVASRGELFVTTKLSMADAHPPRVVAALRESL 117 >UniRef50_UPI000023D0F1 Cluster: hypothetical protein FG03517.1; n=1; Gibberella zeae PH-1|Rep: hypothetical protein FG03517.1 - Gibberella zeae PH-1 Length = 364 Score = 93.9 bits (223), Expect = 5e-18 Identities = 45/121 (37%), Positives = 74/121 (61%) Frame = +1 Query: 406 NLNVQYLDLYLIHWPQAYKEDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIG 585 NL V+YLDLYLIH+P A+ ++ + ++ +DTWKAME LV+ GL ++IG Sbjct: 142 NLGVEYLDLYLIHYPVAW--------VPETRDVD-NNTSLIDTWKAMEELVRAGLTRNIG 192 Query: 586 VSNFNSKQLERLLQHATVKPVVNQVECHPYLNQKRLKEFCEARGVKITXYSPLGSPDRPW 765 SNF K + ++L+ A+++P ++ E HPYL Q+ +F + +K+ SPL + + + Sbjct: 193 FSNFAPKDINKILKIASIQPYAHEFETHPYLQQQSFVDFHKKENIKVIAASPLANTNPTY 252 Query: 766 G 768 G Sbjct: 253 G 253 Score = 71.7 bits (168), Expect = 2e-11 Identities = 36/81 (44%), Positives = 48/81 (59%) Frame = +3 Query: 150 PVFGXGXWXSKPGXVXXAVKXAIDIGXRHIDCAYVYGNXXXVGXAITSKIKEGVVTRXXL 329 P FG G W + G V AV+ A+ G RHID A ++ N VG IK V+R + Sbjct: 61 PAFGLGTWLAGKGVVVPAVEYALKGGYRHIDTALIWRNEDEVGKG----IKASGVSRDEI 116 Query: 330 FITSKLWNTFHRPDLVRGALQ 392 ++T KLWNT HRP+LVR A++ Sbjct: 117 WVTGKLWNTDHRPELVRKAIE 137 >UniRef50_A7CWF9 Cluster: Aldehyde reductase; n=2; Bacteria|Rep: Aldehyde reductase - Opitutaceae bacterium TAV2 Length = 347 Score = 93.9 bits (223), Expect = 5e-18 Identities = 45/120 (37%), Positives = 66/120 (55%), Gaps = 1/120 (0%) Frame = +1 Query: 406 NLNVQYLDLYLIHWP-QAYKEDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSI 582 +L + YLDLYLIHWP + G + + +++ TW+ +E L GLV+ I Sbjct: 117 DLGLDYLDLYLIHWPFPNFHPPGCDVSSRSPDARPYIHAEFMKTWRQLETLHDRGLVRHI 176 Query: 583 GVSNFNSKQLERLLQHATVKPVVNQVECHPYLNQKRLKEFCEARGVKITXYSPLGSPDRP 762 G SN +L+ LL+ A V+P VN++E HP+ Q L ++ R + Y PLGSP RP Sbjct: 177 GTSNMTIAKLQLLLRDARVRPAVNEMELHPHFQQPALFDYVRVRNIVPVGYCPLGSPGRP 236 Score = 58.4 bits (135), Expect = 2e-07 Identities = 36/100 (36%), Positives = 46/100 (46%), Gaps = 4/100 (4%) Frame = +3 Query: 114 IPVVXFXXGASXPVFGXGXWXSK---PGXVXXAVKXAIDIGXRHIDCAYVYGNXXXVGXA 284 IP GA P G G + S PG V +V A ++G RH DCA VY N +G Sbjct: 16 IPQRTLASGARMPAIGMGTFGSDHAAPGEVAASVYAAAELGYRHFDCAAVYSNEREIGAT 75 Query: 285 ITSKIKEGV-VTRXXLFITSKLWNTFHRPDLVRGALQEXL 401 + + R L+ITSKLWN H V A ++ L Sbjct: 76 FRRILTSNTGIRREDLWITSKLWNDKHAEADVIPAFEKSL 115 >UniRef50_A2QB88 Cluster: Contig An01c0460, complete genome. precursor; n=1; Aspergillus niger|Rep: Contig An01c0460, complete genome. precursor - Aspergillus niger Length = 351 Score = 92.3 bits (219), Expect = 2e-17 Identities = 42/76 (55%), Positives = 51/76 (67%) Frame = +1 Query: 520 DYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQHATVKPVVNQVECHPYLNQKRLKE 699 DY TW AME LV +G +K IGVSNFN +LERLL A + P VNQ+E HPYL Q L Sbjct: 178 DYPSTWAAMESLVDKGKLKMIGVSNFNILKLERLLGSARIPPAVNQIELHPYLPQVELVR 237 Query: 700 FCEARGVKITXYSPLG 747 FC+A G+ + + PLG Sbjct: 238 FCKANGIHLVAHQPLG 253 Score = 49.6 bits (113), Expect = 1e-04 Identities = 33/82 (40%), Positives = 40/82 (48%), Gaps = 2/82 (2%) Frame = +3 Query: 150 PVFGXGXWXSKPGX--VXXAVKXAIDIGXRHIDCAYVYGNXXXVGXAITSKIKEGVVTRX 323 P G G + G V AV A+ G RHID A YGN VG A IKE + R Sbjct: 47 PAVGLGTFQGDAGNRGVKEAVLQALRCGYRHIDTATAYGNEIEVGEA----IKESRIPRE 102 Query: 324 XLFITSKLWNTFHRPDLVRGAL 389 + +T+KL T+HR V AL Sbjct: 103 EIIVTTKLAQTWHRVSDVERAL 124 >UniRef50_Q5HR31 Cluster: Oxidoreductase, aldo/keto reductase family; n=3; Staphylococcus|Rep: Oxidoreductase, aldo/keto reductase family - Staphylococcus epidermidis (strain ATCC 35984 / RP62A) Length = 279 Score = 91.9 bits (218), Expect = 2e-17 Identities = 44/113 (38%), Positives = 68/113 (60%) Frame = +1 Query: 406 NLNVQYLDLYLIHWPQAYKEDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIG 585 NL + YLDL+LIHWP +D Y++++KA+E L +EG +K+IG Sbjct: 96 NLGLDYLDLFLIHWPCE------------------NDQLYIESYKALEHLYEEGKIKAIG 137 Query: 586 VSNFNSKQLERLLQHATVKPVVNQVECHPYLNQKRLKEFCEARGVKITXYSPL 744 V NF LE+L++ + P VNQ+E HPY NQ+ +++FC+ +K+T + PL Sbjct: 138 VCNFKIHHLEKLMKETKITPQVNQIELHPYFNQQDVQDFCDEHDIKVTAWMPL 190 Score = 52.8 bits (121), Expect = 1e-05 Identities = 30/78 (38%), Positives = 37/78 (47%) Frame = +3 Query: 138 GASXPVFGXGXWXSKPGXVXXAVKXAIDIGXRHIDCAYVYGNXXXVGXAITSKIKEGVVT 317 G P G G + + V+ A+D G R D AY YGN +G S +K V Sbjct: 11 GYPMPAVGLGVYKIADEQMEEVVRTALDAGYRAFDTAYFYGNEKALG----SALKHSNVE 66 Query: 318 RXXLFITSKLWNTFHRPD 371 R LFITSKLWN + D Sbjct: 67 RDELFITSKLWNDYQGYD 84 >UniRef50_Q968S3 Cluster: Aldoketoreductase-like protein; n=1; Orconectes limosus|Rep: Aldoketoreductase-like protein - Orconectes limosus (Spinycheek crayfish) Length = 336 Score = 91.9 bits (218), Expect = 2e-17 Identities = 46/127 (36%), Positives = 72/127 (56%), Gaps = 1/127 (0%) Frame = +1 Query: 406 NLNVQYLDLYLIHWPQAYKE-DGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSI 582 NL + Y+DLYL+H+P + D D+ +D+ + W+AME + G K+I Sbjct: 114 NLRLPYVDLYLVHYPCGILDTDRERLSADEVTVDPTTDIHAI--WRAMEAQLAAGKTKNI 171 Query: 583 GVSNFNSKQLERLLQHATVKPVVNQVECHPYLNQKRLKEFCEARGVKITXYSPLGSPDRP 762 G+SNFN+ Q++R+++ V+P V QVE H Y+ Q L+ FC + + + PLG P R Sbjct: 172 GLSNFNADQVQRIIKGCQVRPAVLQVEVHVYMQQGALRAFCAQHDIVVCAFCPLGGPFRL 231 Query: 763 WGQARRP 783 +A RP Sbjct: 232 IRKASRP 238 Score = 50.8 bits (116), Expect = 5e-05 Identities = 35/102 (34%), Positives = 47/102 (46%), Gaps = 6/102 (5%) Frame = +3 Query: 114 IPVVXFXXGASXPVFGXGXWX-SKPGX-----VXXAVKXAIDIGXRHIDCAYVYGNXXXV 275 IP + G+ PV G G + G V ++ A++ G RH D A YGN + Sbjct: 11 IPTILLNSGSHIPVMGLGTGSLGRNGKMSEEAVTAVLETALECGYRHFDSAAYYGNEAII 70 Query: 276 GXAITSKIKEGVVTRXXLFITSKLWNTFHRPDLVRGALQEXL 401 G + I EG V R LFIT+KL +R V LQ+ L Sbjct: 71 GQVLRRWISEGKVKREELFITTKLPTRGNREKDVARFLQKSL 112 >UniRef50_Q8WRT0 Cluster: 3-dehydrecdysone 3b-reductase; n=1; Trichoplusia ni|Rep: 3-dehydrecdysone 3b-reductase - Trichoplusia ni (Cabbage looper) Length = 308 Score = 91.9 bits (218), Expect = 2e-17 Identities = 48/113 (42%), Positives = 66/113 (58%) Frame = +1 Query: 409 LNVQYLDLYLIHWPQAYKEDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGV 588 L + Y+DLYLIH P+A E+G P D +D ++TW ME K GL KSIGV Sbjct: 123 LGLSYVDLYLIHSPEATNENGD--PVD---------IDVLNTWNGMEEAKKLGLAKSIGV 171 Query: 589 SNFNSKQLERLLQHATVKPVVNQVECHPYLNQKRLKEFCEARGVKITXYSPLG 747 SNF++ L+RL+ + P VNQ+E HP Q++L RG+++ YSP G Sbjct: 172 SNFDTALLDRLIAGSNTVPAVNQIEVHPSKTQEKLVADSHERGIEVMAYSPFG 224 Score = 64.5 bits (150), Expect = 4e-09 Identities = 34/70 (48%), Positives = 41/70 (58%) Frame = +3 Query: 192 VXXAVKXAIDIGXRHIDCAYVYGNXXXVGXAITSKIKEGVVTRXXLFITSKLWNTFHRPD 371 V AV AI G RHID A +YGN VG I I++G+V R LF+T+KLWN H Sbjct: 51 VRQAVLWAIQAGYRHIDTAALYGNEEEVGKGIADAIQQGLVKREELFVTTKLWNDKHGRH 110 Query: 372 LVRGALQEXL 401 V AL+E L Sbjct: 111 QVVPALRESL 120 >UniRef50_Q0CLQ2 Cluster: Putative uncharacterized protein; n=1; Aspergillus terreus NIH2624|Rep: Putative uncharacterized protein - Aspergillus terreus (strain NIH 2624) Length = 301 Score = 91.9 bits (218), Expect = 2e-17 Identities = 46/108 (42%), Positives = 67/108 (62%), Gaps = 4/108 (3%) Frame = +1 Query: 439 IHWPQAYKEDG-SLFPTDQ-SGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQL 612 IHWP A++ +L P D S + + +++ DTW A+E LV G V+SIGVSNF +++ Sbjct: 128 IHWPVAFEHTNETLTPIDPVSKRFRLANIPIADTWAALEKLVDAGKVRSIGVSNFTIEKI 187 Query: 613 ERLLQHATVKPVVNQVECHPYLNQKRLKEFCEARGVKI--TXYSPLGS 750 E LL+ A + P VNQ+E HPYL Q L ++ + + I YSPLG+ Sbjct: 188 EELLKTARIPPAVNQIEAHPYLQQPALHKYLKEKVTNILSVAYSPLGN 235 Score = 73.3 bits (172), Expect = 8e-12 Identities = 41/96 (42%), Positives = 50/96 (52%) Frame = +3 Query: 138 GASXPVFGXGXWXSKPGXVXXAVKXAIDIGXRHIDCAYVYGNXXXVGXAITSKIKEGVVT 317 G P G G W SKP V AV+ A+ +G RHID A Y N VG + K+ V Sbjct: 12 GYDMPAVGLGTWLSKPHEVENAVETALRLGYRHIDAAACYLNENEVG----NGWKKSGVP 67 Query: 318 RXXLFITSKLWNTFHRPDLVRGALQEXLXQSERSVL 425 R +FITSKLWNT H PD V A+ + L + L Sbjct: 68 RDQIFITSKLWNTHHHPDHVEEAVNKTLKDLQTDYL 103 >UniRef50_Q7R2T6 Cluster: GLP_291_56367_57278; n=1; Giardia lamblia ATCC 50803|Rep: GLP_291_56367_57278 - Giardia lamblia ATCC 50803 Length = 303 Score = 91.5 bits (217), Expect = 3e-17 Identities = 45/116 (38%), Positives = 61/116 (52%), Gaps = 2/116 (1%) Frame = +1 Query: 406 NLNVQYLDLYLIHWPQAYKE--DGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKS 579 +L ++YLD++L+HWP A K D +D G TW+AME V + + Sbjct: 90 DLQLEYLDVFLMHWPLAIKHLADRDYASSDGKGGTLLGTTPIRKTWEAMEACVDKKQTRF 149 Query: 580 IGVSNFNSKQLERLLQHATVKPVVNQVECHPYLNQKRLKEFCEARGVKITXYSPLG 747 IGVSN + L LL + +KP NQ E PY RL EFC + G+ +T Y PLG Sbjct: 150 IGVSNMGTAMLVDLLSYCRIKPFTNQFESQPYFPNDRLIEFCNSNGIYVTAYRPLG 205 Score = 56.4 bits (130), Expect = 9e-07 Identities = 27/69 (39%), Positives = 36/69 (52%), Gaps = 2/69 (2%) Frame = +3 Query: 201 AVKXAIDIGXRHIDCAYVYGNXXXVGXAITSKIKEGV--VTRXXLFITSKLWNTFHRPDL 374 A++ A+ +G RH DCAY YGN +G + V R L+I SKLW FH P+ Sbjct: 20 AIRSAVKLGYRHFDCAYRYGNERMIGEVFKEIFNDDSYGVKREDLWIVSKLWPNFHEPEK 79 Query: 375 VRGALQEXL 401 V + E L Sbjct: 80 VAYQISETL 88 >UniRef50_Q24C22 Cluster: Oxidoreductase, aldo/keto reductase family protein; n=4; Oligohymenophorea|Rep: Oxidoreductase, aldo/keto reductase family protein - Tetrahymena thermophila SB210 Length = 297 Score = 91.1 bits (216), Expect = 4e-17 Identities = 48/113 (42%), Positives = 68/113 (60%), Gaps = 1/113 (0%) Frame = +1 Query: 409 LNVQYLDLYLIHWPQAYKEDGSLFPTD-QSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIG 585 LN++YLD LIHWP K L P D ++ +I+ ++TWKA+ L K G++K IG Sbjct: 109 LNIKYLDCVLIHWPGVSK----LPPNDPKNAQIR------LETWKALIELRKAGVIKHIG 158 Query: 586 VSNFNSKQLERLLQHATVKPVVNQVECHPYLNQKRLKEFCEARGVKITXYSPL 744 VSNFN L+ L++ + KP +NQ E HP K+ EFC+ G+ + YSPL Sbjct: 159 VSNFNINHLQHLIEKSEFKPEMNQFEIHPLCFNKKTIEFCQKNGILVEAYSPL 211 >UniRef50_Q4PHK0 Cluster: Putative uncharacterized protein; n=1; Ustilago maydis|Rep: Putative uncharacterized protein - Ustilago maydis (Smut fungus) Length = 355 Score = 91.1 bits (216), Expect = 4e-17 Identities = 49/126 (38%), Positives = 66/126 (52%), Gaps = 2/126 (1%) Frame = +1 Query: 409 LNVQYLDLYLIHWP-QAYKEDGSLFPTDQSGKIQFS-DVDYVDTWKAMEPLVKEGLVKSI 582 L + Y+DL L+HWP K P ++ G D TW+ ME L G K+I Sbjct: 130 LGLDYVDLLLVHWPVPLVKRGDEKIPLNEDGSRAIDRDWSPEQTWELMEKLPATGKTKAI 189 Query: 583 GVSNFNSKQLERLLQHATVKPVVNQVECHPYLNQKRLKEFCEARGVKITXYSPLGSPDRP 762 GVSN++ L++LL A + P NQVE HP+L Q L ++C +G+ YSPLGS P Sbjct: 190 GVSNWSIAFLDKLLAKAKIVPAANQVELHPFLPQHELVKYCHDKGILPQAYSPLGSSGGP 249 Query: 763 WGQARR 780 Q R Sbjct: 250 VLQDER 255 Score = 42.3 bits (95), Expect(2) = 1e-08 Identities = 21/45 (46%), Positives = 22/45 (48%) Frame = +3 Query: 105 APXIPVVXFXXGASXPVFGXGXWXSKPGXVXXAVKXAIDIGXRHI 239 AP GA PV G G W S PG V AV+ AI G RHI Sbjct: 8 APGQKTFKLNTGAEIPVIGLGTWQSAPGEVAKAVESAIKAGYRHI 52 Score = 39.9 bits (89), Expect(2) = 1e-08 Identities = 19/42 (45%), Positives = 25/42 (59%) Frame = +3 Query: 240 DCAYVYGNXXXVGXAITSKIKEGVVTRXXLFITSKLWNTFHR 365 D A++YGN VG I K V R LF+T+K+W T+HR Sbjct: 80 DAAWIYGNENEVGQGI----KASGVPRSELFVTTKIWCTYHR 117 >UniRef50_Q9ZBW7 Cluster: Putative oxidoreductase; n=2; Actinomycetales|Rep: Putative oxidoreductase - Streptomyces coelicolor Length = 277 Score = 90.2 bits (214), Expect = 6e-17 Identities = 50/114 (43%), Positives = 65/114 (57%) Frame = +1 Query: 409 LNVQYLDLYLIHWPQAYKEDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGV 588 L ++YLDLYLIHWP KE YVDT+KA E L+ +G V++IGV Sbjct: 99 LGLEYLDLYLIHWPMPAKER------------------YVDTYKAFEKLLADGRVRAIGV 140 Query: 589 SNFNSKQLERLLQHATVKPVVNQVECHPYLNQKRLKEFCEARGVKITXYSPLGS 750 SNF + LERL +V P VNQ+E HP+L Q +E +G+ +SPLGS Sbjct: 141 SNFLPEHLERLTAETSVIPAVNQIELHPHLQQHAAREVHAEQGIATEAWSPLGS 194 Score = 56.4 bits (130), Expect = 9e-07 Identities = 29/85 (34%), Positives = 40/85 (47%) Frame = +3 Query: 102 MAPXIPVVXFXXGASXPVFGXGXWXSKPGXVXXAVKXAIDIGXRHIDCAYVYGNXXXVGX 281 M+ +P + G P G G W AV A++ G R ID A +YGN G Sbjct: 1 MSSKVPPIILNNGVEMPQLGFGVWQVPDDDAQTAVALALEAGYRSIDTAAIYGNEEGTGR 60 Query: 282 AITSKIKEGVVTRXXLFITSKLWNT 356 AI + + R LF+T+KLWN+ Sbjct: 61 AIAA----SGLAREDLFVTTKLWNS 81 >UniRef50_Q1VRG6 Cluster: YvgN; n=1; Psychroflexus torquis ATCC 700755|Rep: YvgN - Psychroflexus torquis ATCC 700755 Length = 280 Score = 89.4 bits (212), Expect = 1e-16 Identities = 49/114 (42%), Positives = 65/114 (57%), Gaps = 2/114 (1%) Frame = +1 Query: 409 LNVQYLDLYLIHWPQAYKEDGSLFPTDQSGKIQFSDVDYV--DTWKAMEPLVKEGLVKSI 582 L++ Y+DLYLIHWP + I + D DTW+AME L EG +KS+ Sbjct: 95 LDLNYIDLYLIHWP--------------ANAINYKDWQKTNADTWRAMEELQAEGKIKSL 140 Query: 583 GVSNFNSKQLERLLQHATVKPVVNQVECHPYLNQKRLKEFCEARGVKITXYSPL 744 GVSNF + LE L Q A V P VNQ+E HP Q ++ EFC+ G+ + +SPL Sbjct: 141 GVSNFWPEHLEALFQTAKVSPSVNQIEFHPGYWQPQVTEFCKNHGIAVESWSPL 194 Score = 39.9 bits (89), Expect = 0.086 Identities = 29/89 (32%), Positives = 43/89 (48%), Gaps = 1/89 (1%) Frame = +3 Query: 138 GASXPVFGXGXWXSKPGXVXXAV-KXAIDIGXRHIDCAYVYGNXXXVGXAITSKIKEGVV 314 G P+ G G + + ++ K A+ +G R ID +Y N VG AI ++ GV+ Sbjct: 8 GNRIPIVGFGTYKANEEEGIKSIQKSALTLGYRLIDTVAIYQNEEAVGKAIKAR---GVL 64 Query: 315 TRXXLFITSKLWNTFHRPDLVRGALQEXL 401 R +F+T+KLW R AL E L Sbjct: 65 -REEIFVTTKLWRENLGYKQTRIALDESL 92 >UniRef50_Q6WGK4 Cluster: Aldose reductase; n=1; Pristionchus pacificus|Rep: Aldose reductase - Pristionchus pacificus Length = 293 Score = 89.4 bits (212), Expect = 1e-16 Identities = 44/116 (37%), Positives = 62/116 (53%) Frame = +1 Query: 406 NLNVQYLDLYLIHWPQAYKEDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIG 585 +L Y+DL LIHWP S ++ +F YV+ +E L+ EG ++SIG Sbjct: 103 DLQTPYIDLVLIHWPGT-----SRLKSNHKDNAKFRAETYVE----LETLMDEGKIRSIG 153 Query: 586 VSNFNSKQLERLLQHATVKPVVNQVECHPYLNQKRLKEFCEARGVKITXYSPLGSP 753 VSN+ K LE LL + P +NQ ECHP+ L E+C+ +G+ YS LG P Sbjct: 154 VSNYEIKHLETLLAECRILPAINQCECHPHFRNSELAEYCKEKGIHFQAYSSLGGP 209 Score = 34.7 bits (76), Expect = 3.3 Identities = 19/67 (28%), Positives = 33/67 (49%), Gaps = 1/67 (1%) Frame = +3 Query: 150 PVFGXGXWXSKPGXVXX-AVKXAIDIGXRHIDCAYVYGNXXXVGXAITSKIKEGVVTRXX 326 P+ G G + + V + A +G R ID A +Y N +G + +++ + R Sbjct: 17 PMIGVGTYQVQSQSVLTDTIDEAFRLGYRFIDTAQIYRNEAILGRILPDLLEKHSLKRED 76 Query: 327 LFITSKL 347 +FITSK+ Sbjct: 77 IFITSKV 83 >UniRef50_Q96JD6-2 Cluster: Isoform 2 of Q96JD6 ; n=4; Catarrhini|Rep: Isoform 2 of Q96JD6 - Homo sapiens (Human) Length = 263 Score = 89.0 bits (211), Expect = 1e-16 Identities = 43/84 (51%), Positives = 48/84 (57%) Frame = +3 Query: 150 PVFGXGXWXSKPGXVXXAVKXAIDIGXRHIDCAYVYGNXXXVGXAITSKIKEGVVTRXXL 329 P G W + PG V AVK AID G RH DCAY Y N VG I KIKEG V R L Sbjct: 5 PAVGLSSWKASPGKVTEAVKEAIDAGYRHFDCAYFYHNEREVGAGIRCKIKEGAVRREDL 64 Query: 330 FITSKLWNTFHRPDLVRGALQEXL 401 FI +KLW T H+ LV A ++ L Sbjct: 65 FIATKLWCTCHKKSLVETACRKSL 88 Score = 82.6 bits (195), Expect = 1e-14 Identities = 49/112 (43%), Positives = 62/112 (55%), Gaps = 21/112 (18%) Frame = +1 Query: 388 CRXPWXNLNVQYLDLYLIHWPQAYKEDGSLF-------------------PTDQSGKIQF 510 CR L + YLDLYLIHWP +K + P D+S + Sbjct: 84 CRKSLKALKLNYLDLYLIHWPMGFKPPHPEWIMSCSELSFCLSHPRVQDLPLDESNMVIP 143 Query: 511 SDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQHATV--KPVVNQV 660 SD D++DTW+AME LV GLVK+IGVSNFN +QLERLL + KP+ NQ+ Sbjct: 144 SDTDFLDTWEAMEDLVITGLVKNIGVSNFNHEQLERLLNKPGLRFKPLTNQI 195 >UniRef50_Q4Q5N9 Cluster: Prostaglandin f synthase, putative; n=7; cellular organisms|Rep: Prostaglandin f synthase, putative - Leishmania major Length = 279 Score = 89.0 bits (211), Expect = 1e-16 Identities = 45/113 (39%), Positives = 64/113 (56%) Frame = +1 Query: 409 LNVQYLDLYLIHWPQAYKEDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGV 588 L V+Y+DLYLIHWP + Y++TW+A E L + V++IGV Sbjct: 99 LGVEYVDLYLIHWPGPNRS-------------------YIETWRAFEKLYEMKKVRAIGV 139 Query: 589 SNFNSKQLERLLQHATVKPVVNQVECHPYLNQKRLKEFCEARGVKITXYSPLG 747 SNF L+ LL + TV P+VNQVE HP+ QK L+ +C + + +T + PLG Sbjct: 140 SNFEPHHLDDLLANCTVPPMVNQVEMHPHFQQKALRAYCAEKNIAVTAWRPLG 192 Score = 59.7 bits (138), Expect = 1e-07 Identities = 33/98 (33%), Positives = 46/98 (46%) Frame = +3 Query: 102 MAPXIPVVXFXXGASXPVFGXGXWXSKPGXVXXAVKXAIDIGXRHIDCAYVYGNXXXVGX 281 MA V G P G G W +K G +K A++ G RH+D A+ Y N VG Sbjct: 1 MAVKCTHVTLSNGVQVPQLGIGTWEAKDGNEVVNIKWAVNAGYRHVDTAHYYKNEKGVGQ 60 Query: 282 AITSKIKEGVVTRXXLFITSKLWNTFHRPDLVRGALQE 395 I+ E V R +F+T+KLWN H + A ++ Sbjct: 61 GIS----ECGVPRSDIFVTTKLWNYDHGYESALAAFEQ 94 >UniRef50_A3LTU8 Cluster: D-arabinose dehydrogenase; n=5; Saccharomycetales|Rep: D-arabinose dehydrogenase - Pichia stipitis (Yeast) Length = 326 Score = 89.0 bits (211), Expect = 1e-16 Identities = 50/129 (38%), Positives = 75/129 (58%), Gaps = 10/129 (7%) Frame = +1 Query: 406 NLNVQYLDLYLIHWPQAYKEDGSLFPT---DQSGKIQFSD-----VDYVDTWKAMEPLVK 561 +L + Y+DL+L HWP D + P D+ GK+ + D + Y+D + ++E ++ Sbjct: 103 DLGLDYVDLFLQHWPVVLHGDENGLPPQPRDKDGKLIYDDDPVSGIKYIDAYHSLEDIMD 162 Query: 562 E-GLVKSIGVSNFNSKQLERLLQHATV-KPVVNQVECHPYLNQKRLKEFCEARGVKITXY 735 VKSIGVSN++ +L +LL KPVVNQ+E HP L Q+ L ++C GV I+ Y Sbjct: 163 NTSKVKSIGVSNYSIPKLRKLLAAVRKHKPVVNQIEYHPLLPQQDLVKYCYDNGVHISAY 222 Query: 736 SPLGSPDRP 762 SP+GS P Sbjct: 223 SPVGSNGAP 231 Score = 57.6 bits (133), Expect = 4e-07 Identities = 29/77 (37%), Positives = 41/77 (53%), Gaps = 1/77 (1%) Frame = +3 Query: 138 GASXPVFGXGXWXSK-PGXVXXAVKXAIDIGXRHIDCAYVYGNXXXVGXAITSKIKEGVV 314 G + P G G + P + V A+ G RHID A+ YG +G A+ +EG+V Sbjct: 15 GKTIPALGLGTVPPEDPHELKEQVITAVKAGYRHIDTAWYYGTEEYIGQALKQLFEEGIV 74 Query: 315 TRXXLFITSKLWNTFHR 365 R LFIT+K+W +F R Sbjct: 75 KREDLFITTKVWPSFWR 91 >UniRef50_Q5V6N9 Cluster: Alcohol dehydrogenase; n=2; Halobacteriaceae|Rep: Alcohol dehydrogenase - Haloarcula marismortui (Halobacterium marismortui) Length = 667 Score = 89.0 bits (211), Expect = 1e-16 Identities = 45/137 (32%), Positives = 69/137 (50%), Gaps = 15/137 (10%) Frame = +1 Query: 388 CRXPWXNLNVQYLDLYLIHWPQAYKEDGSL---------------FPTDQSGKIQFSDVD 522 CR L + D Y +HWP+A GSL FP + G I+ V Sbjct: 458 CRSSLDELGIDAFDCYALHWPEALAHRGSLTRLAEKSVARQEALTFPKNDRGDIETDSVS 517 Query: 523 YVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQHATVKPVVNQVECHPYLNQKRLKEF 702 W+ +E L + G +++G+ N + QLE +++ TV+P + QVE HPY Q L E+ Sbjct: 518 LQRAWENLEALHERGWTRTLGLCNVSQTQLETVIETGTVRPALVQVERHPYQPQTDLIEY 577 Query: 703 CEARGVKITXYSPLGSP 753 C RG+++ +SPL +P Sbjct: 578 CHERGIRVVAHSPLSAP 594 Score = 39.5 bits (88), Expect = 0.11 Identities = 19/55 (34%), Positives = 29/55 (52%) Frame = +3 Query: 201 AVKXAIDIGXRHIDCAYVYGNXXXVGXAITSKIKEGVVTRXXLFITSKLWNTFHR 365 ++ A+D G R +D A +YGN +G + + G R +FI K+W T HR Sbjct: 399 SIAAALDAGYRLLDSAELYGNEHRIGRILAA---PGAPDRRRVFILGKVWRTNHR 450 >UniRef50_UPI0000DB6EE9 Cluster: PREDICTED: similar to C35D10.6; n=2; Endopterygota|Rep: PREDICTED: similar to C35D10.6 - Apis mellifera Length = 292 Score = 88.6 bits (210), Expect = 2e-16 Identities = 46/114 (40%), Positives = 63/114 (55%), Gaps = 1/114 (0%) Frame = +1 Query: 412 NVQYLDLYLIHWPQAYKEDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVS 591 N Y+DLYLIHWP A + P + TW + L K+G ++SIGVS Sbjct: 106 NTTYIDLYLIHWPGATR-----IPETSTNNPSLR----AKTWNKLVDLKKQGFIRSIGVS 156 Query: 592 NFNSKQLERLLQHAT-VKPVVNQVECHPYLNQKRLKEFCEARGVKITXYSPLGS 750 NF K L+ LLQ+ + P VNQVE HP+ Q+ L ++C +G+ I YS LG+ Sbjct: 157 NFTIKHLQELLQNCKDILPAVNQVELHPHYRQEELIKYCNEKGIHIQAYSSLGT 210 >UniRef50_P28475 Cluster: NADP-dependent D-sorbitol-6-phosphate dehydrogenase; n=71; Magnoliophyta|Rep: NADP-dependent D-sorbitol-6-phosphate dehydrogenase - Malus domestica (Apple) (Malus sylvestris) Length = 310 Score = 88.6 bits (210), Expect = 2e-16 Identities = 45/124 (36%), Positives = 65/124 (52%), Gaps = 4/124 (3%) Frame = +1 Query: 388 CRXPWXNLNVQYLDLYLIHWPQAYKEDGSLFPTDQSGKIQFSDVDYV----DTWKAMEPL 555 C+ L + YLDLYL+H+P K + G+ + D+D TW+ ME Sbjct: 90 CKNSLEKLQIDYLDLYLVHYPMPTKHNAIGKTASLLGEDKVLDIDVTISLQQTWEGMEKT 149 Query: 556 VKEGLVKSIGVSNFNSKQLERLLQHATVKPVVNQVECHPYLNQKRLKEFCEARGVKITXY 735 V GLV+SIG+SN+ L ++ +KP V+Q E HPY + L +FC GV T + Sbjct: 150 VSLGLVRSIGLSNYELFLTRDCLAYSKIKPAVSQFETHPYFQRDSLVKFCMKHGVLPTAH 209 Query: 736 SPLG 747 +PLG Sbjct: 210 TPLG 213 Score = 67.3 bits (157), Expect = 5e-10 Identities = 32/80 (40%), Positives = 41/80 (51%) Frame = +3 Query: 123 VXFXXGASXPVFGXGXWXSKPGXVXXAVKXAIDIGXRHIDCAYVYGNXXXVGXAITSKIK 302 V G PV G G W + + + AI IG RH DCA Y + VG A+ K Sbjct: 4 VTLSSGYEMPVIGLGLWRLEKDELKEVILNAIKIGYRHFDCAAHYKSEADVGEALAEAFK 63 Query: 303 EGVVTRXXLFITSKLWNTFH 362 G+V R LFIT+K+WN+ H Sbjct: 64 TGLVKREELFITTKIWNSDH 83 >UniRef50_A4RQH8 Cluster: Predicted protein; n=2; Ostreococcus|Rep: Predicted protein - Ostreococcus lucimarinus CCE9901 Length = 337 Score = 88.2 bits (209), Expect = 2e-16 Identities = 46/115 (40%), Positives = 65/115 (56%), Gaps = 2/115 (1%) Frame = +1 Query: 406 NLNVQYLDLYLIHWPQAYKEDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIG 585 +L V YLDLYLIHWP A+K G++ D I + W +E V +GLV+ IG Sbjct: 102 DLGVGYLDLYLIHWPVAWKR-GTVLQPDAEASI-------AECWSELERCVADGLVRHIG 153 Query: 586 VSNFNSKQLERLLQ--HATVKPVVNQVECHPYLNQKRLKEFCEARGVKITXYSPL 744 VSNFN QL L ++P NQ+E HP + L ++ +++G+ +T YSPL Sbjct: 154 VSNFNEAQLAALCDDPRTKIQPACNQIESHPLWSNDSLVKYSQSKGLTVTAYSPL 208 Score = 78.6 bits (185), Expect = 2e-13 Identities = 40/100 (40%), Positives = 50/100 (50%) Frame = +3 Query: 102 MAPXIPVVXFXXGASXPVFGXGXWXSKPGXVXXAVKXAIDIGXRHIDCAYVYGNXXXVGX 281 MAP +V G P G G W ++P V AV+ A+ G H+DCA Y N VG Sbjct: 1 MAPSTILVNDANGLRIPRVGLGTWKARPNEVRDAVRDALGAGYAHVDCAAAYANESEVGE 60 Query: 282 AITSKIKEGVVTRXXLFITSKLWNTFHRPDLVRGALQEXL 401 A+ + G R +F+TSKLWN RP VR AL L Sbjct: 61 ALREAFERGDAKREDVFVTSKLWNDRRRPRDVREALMTTL 100 >UniRef50_Q1DLF1 Cluster: Putative uncharacterized protein; n=1; Coccidioides immitis|Rep: Putative uncharacterized protein - Coccidioides immitis Length = 324 Score = 88.2 bits (209), Expect = 2e-16 Identities = 42/85 (49%), Positives = 54/85 (63%) Frame = +1 Query: 532 TWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQHATVKPVVNQVECHPYLNQKRLKEFCEA 711 TWKAME LV +G K IGVSNF++ +L+RLL + PVVNQVE +PY QK+L FC Sbjct: 145 TWKAMENLVDQGKAKLIGVSNFSTPKLKRLLSVCRIFPVVNQVELNPYFPQKQLLRFCHE 204 Query: 712 RGVKITXYSPLGSPDRPWGQARRPP 786 + +T Y PLG P+ R+ P Sbjct: 205 HEIHVTAYGPLGCTPVPYLIGRKTP 229 Score = 48.0 bits (109), Expect = 3e-04 Identities = 35/104 (33%), Positives = 48/104 (46%), Gaps = 1/104 (0%) Frame = +3 Query: 186 GXVXXAVKXAIDIGXRHIDCAYVYGNXXXVGXAITSKIKEGVVTRXXLFITSKLWNTFHR 365 G V +V A+ IG RHID A YG V I + I+ V R +F+ +KL N FH Sbjct: 34 GSVKDSVLHALKIGYRHIDAALAYG-WGSVERGIGAAIRASGVPREDVFVVTKLHNCFHA 92 Query: 366 PDLVRGALQEXLXQSERSVLGSVPDTLAPGLQGRRLSLPD-RPI 494 P+ V + L + LG VP G + PD +P+ Sbjct: 93 PEDVEVGMNMSL---KNLGLGYVPYAYTKGENYSTVRKPDGKPV 133 >UniRef50_Q5FT75 Cluster: Putative 2,5-diketo-D-gluconic acid reductase; n=1; Gluconobacter oxydans|Rep: Putative 2,5-diketo-D-gluconic acid reductase - Gluconobacter oxydans (Gluconobacter suboxydans) Length = 279 Score = 87.8 bits (208), Expect = 3e-16 Identities = 48/108 (44%), Positives = 60/108 (55%) Frame = +1 Query: 424 LDLYLIHWPQAYKEDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNS 603 LDLYLIHWP + YV+TWKA+ L K G VKSIGVSNF S Sbjct: 106 LDLYLIHWPMP------------------AQGQYVETWKALVELKKSGRVKSIGVSNFES 147 Query: 604 KQLERLLQHATVKPVVNQVECHPYLNQKRLKEFCEARGVKITXYSPLG 747 + LER++ V PVVNQ+E HP Q+ L+EF E ++ + PLG Sbjct: 148 EHLERIMDATGVVPVVNQIELHPDFQQRALREFHEKHNIRTESWRPLG 195 Score = 53.2 bits (122), Expect = 9e-06 Identities = 32/102 (31%), Positives = 45/102 (44%) Frame = +3 Query: 120 VVXFXXGASXPVFGXGXWXSKPGXVXXAVKXAIDIGXRHIDCAYVYGNXXXVGXAITSKI 299 V+ F G + P G G W + P VK A+ +G R +D A +Y N VG Sbjct: 13 VISFHDGHTMPQIGLGVWETPPDETAEVVKEAVKLGYRSVDTARLYKNEEGVG------- 65 Query: 300 KEGVVTRXXLFITSKLWNTFHRPDLVRGALQEXLXQSERSVL 425 +G+ +F+T+KLWN D A +E R VL Sbjct: 66 -KGLEDHPEIFLTTKLWNDEQGYDSTLRAYEESARLLRRPVL 106 >UniRef50_A0JX62 Cluster: 2,5-didehydrogluconate reductase; n=9; Bacteria|Rep: 2,5-didehydrogluconate reductase - Arthrobacter sp. (strain FB24) Length = 291 Score = 87.8 bits (208), Expect = 3e-16 Identities = 47/114 (41%), Positives = 68/114 (59%) Frame = +1 Query: 406 NLNVQYLDLYLIHWPQAYKEDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIG 585 NL ++Y+DLYLIHWP A + LF ++++AME L +EG +++IG Sbjct: 114 NLGMEYVDLYLIHWPCARR---GLF---------------TESYRAMETLYREGRIRAIG 155 Query: 586 VSNFNSKQLERLLQHATVKPVVNQVECHPYLNQKRLKEFCEARGVKITXYSPLG 747 VSNF LE LL+ A V P VNQ+E HP+L Q L++ + G++ +SPLG Sbjct: 156 VSNFQPAHLEHLLETAEVVPAVNQIELHPWLQQDELRQLHDRLGIRTEAWSPLG 209 Score = 39.9 bits (89), Expect = 0.086 Identities = 29/98 (29%), Positives = 39/98 (39%), Gaps = 13/98 (13%) Frame = +3 Query: 117 PVVXFXXGASXPVFGXGXWXSKPGXVXXAVKXAIDIGXRHIDCAYVYGNXXXVGXAI--- 287 P + G G G + P V A++ G RH D A +YGN VG AI Sbjct: 5 PRLSLNNGVLIDQLGFGLYKVPPADAAGLVTMALEAGYRHFDTAAMYGNETGVGKAIGAL 64 Query: 288 ----------TSKIKEGVVTRXXLFITSKLWNTFHRPD 371 S ++R LF+T+K+WN H D Sbjct: 65 AGFAGGGPAGGSGEAAPSLSREDLFVTTKVWNDDHGYD 102 >UniRef50_Q5TNP1 Cluster: ENSANGP00000029046; n=2; Culicidae|Rep: ENSANGP00000029046 - Anopheles gambiae str. PEST Length = 331 Score = 87.8 bits (208), Expect = 3e-16 Identities = 48/117 (41%), Positives = 62/117 (52%), Gaps = 2/117 (1%) Frame = +1 Query: 406 NLNVQYLDLYLIHWPQAYKEDGSLFPTDQSGKIQFSDVDY-VDTWKAMEPLVKEGLVKSI 582 NL YLDLYLIHWP + G +V Y +W A+ L +EG ++SI Sbjct: 130 NLQTDYLDLYLIHWPGVSGKCGRWKWLFGMQVTHPDNVKYRAASWNALSKLEREGCLRSI 189 Query: 583 GVSNFNSKQLERLLQHAT-VKPVVNQVECHPYLNQKRLKEFCEARGVKITXYSPLGS 750 GVSN+ K L+ +L + P VNQVE HPY Q L E+C G+ + YS LGS Sbjct: 190 GVSNYTVKHLKEMLADCKGIVPAVNQVEWHPYYYQPELLEYCRQHGIFLQAYSSLGS 246 Score = 41.1 bits (92), Expect = 0.037 Identities = 23/71 (32%), Positives = 36/71 (50%), Gaps = 1/71 (1%) Frame = +3 Query: 138 GASXPVFGXGXWXSK-PGXVXXAVKXAIDIGXRHIDCAYVYGNXXXVGXAITSKIKEGVV 314 G P+ G G + + + A++ G RHID A VY N +G A+ + + + + Sbjct: 39 GFDIPLAGFGTYQIHGQELIYQVLDYALEAGYRHIDTAVVYRNEEYIGTALKTLLPKYNL 98 Query: 315 TRXXLFITSKL 347 R +FITSKL Sbjct: 99 KREDIFITSKL 109 >UniRef50_UPI00006CD296 Cluster: oxidoreductase, aldo/keto reductase family protein; n=1; Tetrahymena thermophila SB210|Rep: oxidoreductase, aldo/keto reductase family protein - Tetrahymena thermophila SB210 Length = 295 Score = 87.4 bits (207), Expect = 4e-16 Identities = 45/113 (39%), Positives = 64/113 (56%) Frame = +1 Query: 406 NLNVQYLDLYLIHWPQAYKEDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIG 585 NL Y+DLYL+H+ S PTDQ + + W E LV++GL+++IG Sbjct: 101 NLQTNYIDLYLLHY-------ASSPPTDQ---FELTHKPVFQVWAEFEELVQKGLIRNIG 150 Query: 586 VSNFNSKQLERLLQHATVKPVVNQVECHPYLNQKRLKEFCEARGVKITXYSPL 744 +SNFN + L L + +KPVVNQ+E + Y Q RL EFC+ + +T Y PL Sbjct: 151 ISNFNVQMLLDLYSYCKIKPVVNQIEVNVYCQQPRLLEFCKKLNLHVTAYCPL 203 Score = 54.0 bits (124), Expect = 5e-06 Identities = 34/89 (38%), Positives = 49/89 (55%), Gaps = 4/89 (4%) Frame = +3 Query: 138 GASXPVFGXGXWX--SKPGXVXXAVKXAIDIGXRHIDCAYVYGNXXXVGXAITSKIKEGV 311 G+ PVFG G + SK V ++ A+D+G RHID A +Y N +G A+ KEG Sbjct: 13 GSKLPVFGLGTYKVVSKEEMVTF-LRTALDLGYRHIDTAIMYENEKQIGDALQEIYKEGK 71 Query: 312 VTRXXLFITSKLWNTFHR--PDLVRGALQ 392 R LF+ +KL++ + D VR +LQ Sbjct: 72 YKREDLFLVTKLFSNKNTKVEDQVRQSLQ 100 >UniRef50_Q23320 Cluster: Putative uncharacterized protein; n=4; Caenorhabditis|Rep: Putative uncharacterized protein - Caenorhabditis elegans Length = 320 Score = 87.4 bits (207), Expect = 4e-16 Identities = 48/117 (41%), Positives = 64/117 (54%) Frame = +1 Query: 409 LNVQYLDLYLIHWPQAYKEDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGV 588 L + Y+DLYL H P + K+DGS SDV D W+ E + GL K+IGV Sbjct: 103 LRLDYVDLYLAHIPASTKDDGSFR----------SDVKVEDIWRGFEKVYGLGLTKAIGV 152 Query: 589 SNFNSKQLERLLQHATVKPVVNQVECHPYLNQKRLKEFCEARGVKITXYSPLGSPDR 759 SNFN Q+ R++ V +Q+E H YL QK +E C+ + IT Y+ LGSP R Sbjct: 153 SNFNESQIVRIMNIQKVPIHASQLELHLYLPQKAHRELCKKHNILITAYATLGSPGR 209 Score = 60.5 bits (140), Expect = 6e-08 Identities = 31/100 (31%), Positives = 47/100 (47%) Frame = +3 Query: 102 MAPXIPVVXFXXGASXPVFGXGXWXSKPGXVXXAVKXAIDIGXRHIDCAYVYGNXXXVGX 281 M+ +P+ G P G G W ++ A+ G RHID A +Y N +G Sbjct: 1 MSSKVPIFTLSNGVLMPSIGLGTWQMTGEEGKTVIRNAVLAGYRHIDTATLYQNEHQIGD 60 Query: 282 AITSKIKEGVVTRXXLFITSKLWNTFHRPDLVRGALQEXL 401 A+ EG++ R +FIT+K + PD+V AL+ L Sbjct: 61 ALAELFAEGILKREDIFITTKAFCHEVAPDVVEEALRNSL 100 >UniRef50_Q18483 Cluster: Putative uncharacterized protein; n=2; Caenorhabditis|Rep: Putative uncharacterized protein - Caenorhabditis elegans Length = 287 Score = 87.0 bits (206), Expect = 6e-16 Identities = 46/116 (39%), Positives = 64/116 (55%) Frame = +1 Query: 406 NLNVQYLDLYLIHWPQAYKEDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIG 585 NL V+YLDL LIHWP GS ++ + V++W M ++ EG ++S+G Sbjct: 98 NLKVEYLDLLLIHWP------GSSLKSENPANKKLR----VESWNVMCEMMAEGKLRSVG 147 Query: 586 VSNFNSKQLERLLQHATVKPVVNQVECHPYLNQKRLKEFCEARGVKITXYSPLGSP 753 VSNF LE L + + V P VNQVE HP+ +Q L ++C + YS LGSP Sbjct: 148 VSNFEICHLEELKKDSNVVPAVNQVEYHPHFHQDDLVKYCNENNIHFQAYSSLGSP 203 Score = 36.3 bits (80), Expect = 1.1 Identities = 20/67 (29%), Positives = 29/67 (43%), Gaps = 1/67 (1%) Frame = +3 Query: 150 PVFGXGXWX-SKPGXVXXAVKXAIDIGXRHIDCAYVYGNXXXVGXAITSKIKEGVVTRXX 326 P+ G G W K + + G R ID A VY N +G + + + R Sbjct: 12 PLIGIGTWQVQKEEILRQVIDAGFKEGYRFIDTAQVYNNEAKIGRILEKLLPANGLKRED 71 Query: 327 LFITSKL 347 ++ITSKL Sbjct: 72 IWITSKL 78 >UniRef50_Q4WF80 Cluster: Glycerol dehydrogenase (GCY1), putative; n=1; Aspergillus fumigatus|Rep: Glycerol dehydrogenase (GCY1), putative - Aspergillus fumigatus (Sartorya fumigata) Length = 274 Score = 86.2 bits (204), Expect = 1e-15 Identities = 41/81 (50%), Positives = 54/81 (66%) Frame = +1 Query: 520 DYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQHATVKPVVNQVECHPYLNQKRLKE 699 DY +TW+ ME + K G VK+IGV+N++ LE L + TV P VNQVE HP+L Q LKE Sbjct: 106 DY-ETWRQMEEIYKAGKVKAIGVANWSIPYLEELKKKWTVVPAVNQVELHPFLPQHALKE 164 Query: 700 FCEARGVKITXYSPLGSPDRP 762 +C+ G+ + YSPLGS P Sbjct: 165 WCDKHGILLEAYSPLGSEGAP 185 Score = 41.1 bits (92), Expect = 0.037 Identities = 18/38 (47%), Positives = 21/38 (55%) Frame = +3 Query: 138 GASXPVFGXGXWXSKPGXVXXAVKXAIDIGXRHIDCAY 251 GA P G G W S+PG V AV A+ G HID A+ Sbjct: 12 GAQIPAIGLGTWRSEPGQVRQAVSFALKNGYSHIDTAF 49 >UniRef50_A7RRF6 Cluster: Predicted protein; n=2; Nematostella vectensis|Rep: Predicted protein - Nematostella vectensis Length = 275 Score = 85.4 bits (202), Expect = 2e-15 Identities = 47/112 (41%), Positives = 60/112 (53%) Frame = +1 Query: 409 LNVQYLDLYLIHWPQAYKEDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGV 588 L V Y+DLYLIH+P V +W+AM L +GL +SIGV Sbjct: 98 LGVDYVDLYLIHFPVP--------------------AGVVGSWEAMAELQGKGLTRSIGV 137 Query: 589 SNFNSKQLERLLQHATVKPVVNQVECHPYLNQKRLKEFCEARGVKITXYSPL 744 SNFN LE L +H+ + PVVNQ+E HPYL + L +FC + I YSPL Sbjct: 138 SNFNIHHLEALQKHSVIPPVVNQIEVHPYLQMEELVDFCRKHSIAIQAYSPL 189 Score = 35.5 bits (78), Expect = 1.9 Identities = 14/33 (42%), Positives = 22/33 (66%) Frame = +2 Query: 785 QXMEDPKLKXIADRLGKTVAQVLIRYQIDXGXI 883 + + DP L+ + D+ GKT AQVL+R+ + G I Sbjct: 193 EKLHDPLLRSLGDKYGKTPAQVLLRWSLQKGYI 225 >UniRef50_Q8J0K1 Cluster: 4-dihydromethyltrisporate dehydrogenase; n=2; Parasitella parasitica|Rep: 4-dihydromethyltrisporate dehydrogenase - Parasitella parasitica Length = 321 Score = 85.4 bits (202), Expect = 2e-15 Identities = 43/117 (36%), Positives = 69/117 (58%), Gaps = 6/117 (5%) Frame = +1 Query: 415 VQYLDLYLIHWP--QAYKEDGSLFPTD----QSGKIQFSDVDYVDTWKAMEPLVKEGLVK 576 ++Y DLYLIH+P Y + +P + + K+ F + W ME LV+ L + Sbjct: 104 LEYFDLYLIHFPIPLQYVDPAVSYPPEWYVPHADKLNFERSPIHECWAEMEKLVQAKLTR 163 Query: 577 SIGVSNFNSKQLERLLQHATVKPVVNQVECHPYLNQKRLKEFCEARGVKITXYSPLG 747 +IGV+NFN + + LL +A +KP V Q+E HP L Q+RL ++ + +G+++T YS G Sbjct: 164 NIGVANFNCQAILDLLSYAKIKPAVLQIEIHPLLPQERLVKWVQEQGIQVTAYSSFG 220 Score = 69.3 bits (162), Expect = 1e-10 Identities = 37/84 (44%), Positives = 42/84 (50%) Frame = +3 Query: 150 PVFGXGXWXSKPGXVXXAVKXAIDIGXRHIDCAYVYGNXXXVGXAITSKIKEGVVTRXXL 329 P+ G G W + + AI IG R D A YGN VG I IKEG+V R L Sbjct: 16 PLRGFGCWKIEKKDAENTIYQAIKIGYRLFDGACDYGNEVEVGRGINKAIKEGLVKREEL 75 Query: 330 FITSKLWNTFHRPDLVRGALQEXL 401 FI +KLWNTFH VR A L Sbjct: 76 FIVTKLWNTFHSKQHVRTAFDRQL 99 >UniRef50_Q4P4P1 Cluster: Putative uncharacterized protein; n=1; Ustilago maydis|Rep: Putative uncharacterized protein - Ustilago maydis (Smut fungus) Length = 322 Score = 85.4 bits (202), Expect = 2e-15 Identities = 46/121 (38%), Positives = 68/121 (56%), Gaps = 3/121 (2%) Frame = +1 Query: 409 LNVQYLDLYLIHWPQAYKEDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGV 588 LNV Y+D+YL+H P + L + WKA+E V G +K+IGV Sbjct: 113 LNVDYMDMYLMHSPGTMGAEKRL-----------------EAWKALEEAVDAGKIKTIGV 155 Query: 589 SNFNSKQLERLLQHATVKPVVNQVECHPYLNQKRLKEFCEARGVKITXYSPLG---SPDR 759 SNF+ ++L+ LL + +KP VNQ+E HP+ + L+E C +RG+ I YSP+ + DR Sbjct: 156 SNFDVEELDHLLANCRIKPAVNQIESHPFFAHEELREACISRGIHIQAYSPMAQGQALDR 215 Query: 760 P 762 P Sbjct: 216 P 216 Score = 55.6 bits (128), Expect = 2e-06 Identities = 34/89 (38%), Positives = 42/89 (47%), Gaps = 1/89 (1%) Frame = +3 Query: 138 GASXPVFGXGXWXS-KPGXVXXAVKXAIDIGXRHIDCAYVYGNXXXVGXAITSKIKEGVV 314 G P G + + G A K A D G RHID A Y N VG A+ KE V Sbjct: 24 GQEIPQVALGVYKAPNDGSTENACKWAFDAGYRHIDSAARYMNEESVGRALAEWTKENNV 83 Query: 315 TRXXLFITSKLWNTFHRPDLVRGALQEXL 401 R +FITSKLW+ H D A+++ L Sbjct: 84 PRSEIFITSKLWDADH--DKAAAAIEDSL 110 Score = 36.3 bits (80), Expect = 1.1 Identities = 14/37 (37%), Positives = 26/37 (70%) Frame = +2 Query: 785 QXMEDPKLKXIADRLGKTVAQVLIRYQIDXGXIVXPE 895 Q ++ P++K IA + GKT AQ+L+++ + G I+ P+ Sbjct: 211 QALDRPEIKTIASKHGKTPAQILLKWGLTHGNIILPK 247 >UniRef50_Q013C5 Cluster: Glycerol dehydrogenase, putative; n=2; Ostreococcus|Rep: Glycerol dehydrogenase, putative - Ostreococcus tauri Length = 425 Score = 84.6 bits (200), Expect = 3e-15 Identities = 42/116 (36%), Positives = 67/116 (57%) Frame = +1 Query: 409 LNVQYLDLYLIHWPQAYKEDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGV 588 L ++YLDL+ + WP +K + D G ++ +TW A+E V +G VK++GV Sbjct: 211 LGIEYLDLFSLEWPVVHKPGTT--EVDSEGSLE-------ETWAALEKCVADGRVKALGV 261 Query: 589 SNFNSKQLERLLQHATVKPVVNQVECHPYLNQKRLKEFCEARGVKITXYSPLGSPD 756 +NF+ +ERL++ VKP VN+VE HP L Q++L C GV + ++ L + D Sbjct: 262 ANFSVPAVERLMKCCKVKPAVNEVELHPLLAQRKLVGVCRRYGVTVLAHTSLANGD 317 >UniRef50_Q2H1Q3 Cluster: Putative uncharacterized protein; n=1; Chaetomium globosum|Rep: Putative uncharacterized protein - Chaetomium globosum (Soil fungus) Length = 274 Score = 84.6 bits (200), Expect = 3e-15 Identities = 40/95 (42%), Positives = 57/95 (60%), Gaps = 2/95 (2%) Frame = +1 Query: 484 TDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQHATVK--PVVNQ 657 T + K + D D+VDTW+ M+ L+ ++++GVSNF K LERLL + K P VNQ Sbjct: 93 TPEDLKKHYPDWDFVDTWREMQKLMDTNKIRNLGVSNFGIKNLERLLNDPSCKIVPAVNQ 152 Query: 658 VECHPYLNQKRLKEFCEARGVKITXYSPLGSPDRP 762 +E HP +L +C +G+ + YSPLGS D P Sbjct: 153 IELHPGNPSPKLIAYCAEKGIHCSGYSPLGSSDSP 187 >UniRef50_Q568D7 Cluster: Zgc:110366; n=7; Euteleostomi|Rep: Zgc:110366 - Danio rerio (Zebrafish) (Brachydanio rerio) Length = 289 Score = 83.8 bits (198), Expect = 5e-15 Identities = 46/119 (38%), Positives = 61/119 (51%) Frame = +1 Query: 388 CRXPWXNLNVQYLDLYLIHWPQAYKEDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEG 567 CR L V YLDLYL+HWP S+ P S +++ ++TW+A+E L EG Sbjct: 100 CRDSRARLGVDYLDLYLMHWPD------SMVPGRSSQEVR------LETWRALEELYDEG 147 Query: 568 LVKSIGVSNFNSKQLERLLQHATVKPVVNQVECHPYLNQKRLKEFCEARGVKITXYSPL 744 L ++IGVSNF L L + P VNQVE HP+ +L E C + Y PL Sbjct: 148 LCRAIGVSNFLIPHLNELKDSGGIVPHVNQVEFHPFQQPMKLVEHCRKENIVFEGYCPL 206 Score = 41.9 bits (94), Expect = 0.021 Identities = 29/79 (36%), Positives = 38/79 (48%), Gaps = 1/79 (1%) Frame = +3 Query: 117 PVVXFXXGASXPVFGXGXWXSKPGXVXXAVKXAI-DIGXRHIDCAYVYGNXXXVGXAITS 293 P V G + P+ G G G AV A+ + G RHID A YG +G A+T Sbjct: 14 PAVPLHNGLNIPILGLGT-SHYGGYSHEAVLYALQECGIRHIDTAKRYGCEEALGKAVT- 71 Query: 294 KIKEGVVTRXXLFITSKLW 350 E V R L++T+KLW Sbjct: 72 ---ESGVQREELWVTTKLW 87 >UniRef50_Q1U9L6 Cluster: 2,5-didehydrogluconate reductase; n=3; Lactobacillus|Rep: 2,5-didehydrogluconate reductase - Lactobacillus reuteri 100-23 Length = 288 Score = 83.8 bits (198), Expect = 5e-15 Identities = 43/113 (38%), Positives = 64/113 (56%) Frame = +1 Query: 409 LNVQYLDLYLIHWPQAYKEDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGV 588 L + YLDLYLIHWP K+ G D + KI +TW+AME L EG +++IGV Sbjct: 102 LQMDYLDLYLIHWPANEKQFG-----DDAAKIN------AETWRAMEDLYNEGKIRAIGV 150 Query: 589 SNFNSKQLERLLQHATVKPVVNQVECHPYLNQKRLKEFCEARGVKITXYSPLG 747 SNF + L++ A V P V+Q+E HP + ++ +A + + ++PLG Sbjct: 151 SNFMPHHIAELMKTAKVAPAVDQIEVHPGWPHTEVVKYLQAHNILVEAWAPLG 203 Score = 66.1 bits (154), Expect = 1e-09 Identities = 38/96 (39%), Positives = 48/96 (50%) Frame = +3 Query: 138 GASXPVFGXGXWXSKPGXVXXAVKXAIDIGXRHIDCAYVYGNXXXVGXAITSKIKEGVVT 317 G P G G + + AVK AI+ G RHID A VYGN VG IK+ + Sbjct: 16 GVKIPCVGYGTFRTPADVAEQAVKEAIETGYRHIDTAAVYGNEEAVGKG----IKDSGIK 71 Query: 318 RXXLFITSKLWNTFHRPDLVRGALQEXLXQSERSVL 425 R LF+TSKLWNT + + A QE L + + L Sbjct: 72 REDLFVTSKLWNTNRGYEQTKKAFQETLDRLQMDYL 107 >UniRef50_A6RMS0 Cluster: Putative uncharacterized protein; n=1; Botryotinia fuckeliana B05.10|Rep: Putative uncharacterized protein - Botryotinia fuckeliana B05.10 Length = 286 Score = 83.8 bits (198), Expect = 5e-15 Identities = 36/75 (48%), Positives = 49/75 (65%) Frame = +1 Query: 523 YVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQHATVKPVVNQVECHPYLNQKRLKEF 702 Y +TW+AME LV G K+IG+SNFN + +R+L+ A ++P VNQVE HPY Q L F Sbjct: 119 YTETWQAMEKLVDSGKAKAIGLSNFNILKTKRILEIARIRPAVNQVEAHPYFPQHELLAF 178 Query: 703 CEARGVKITXYSPLG 747 CE + + + PLG Sbjct: 179 CEKEHIHLMAHQPLG 193 Score = 42.3 bits (95), Expect = 0.016 Identities = 39/108 (36%), Positives = 47/108 (43%), Gaps = 2/108 (1%) Frame = +3 Query: 138 GASXPVFGXGXWXSKPGX--VXXAVKXAIDIGXRHIDCAYVYGNXXXVGXAITSKIKEGV 311 G++ P G G + G V VK AI G RHID A YGN +G A IKE Sbjct: 13 GSTLPAIGLGTFQGDDGNEKVKNIVKAAIQAGYRHIDGAAAYGNEEAIGDA----IKESG 68 Query: 312 VTRXXLFITSKLWNTFHRPDLVRGALQEXLXQSERSVLGSVPDTLAPG 455 ++R L ++ W H P V AL L E L VP PG Sbjct: 69 ISRDEL---AQPW---HEPKDVERALDLSL---EALGLEYVPHAYLPG 107 >UniRef50_Q6U5V3 Cluster: Putative uncharacterized protein; n=1; Klebsiella pneumoniae|Rep: Putative uncharacterized protein - Klebsiella pneumoniae Length = 279 Score = 83.4 bits (197), Expect = 7e-15 Identities = 45/114 (39%), Positives = 63/114 (55%) Frame = +1 Query: 409 LNVQYLDLYLIHWPQAYKEDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGV 588 L V+YL+L+LIHWP K YV+TW+A L GL++SIGV Sbjct: 97 LGVEYLELFLIHWPIPAKNL------------------YVETWEASIELEASGLIRSIGV 138 Query: 589 SNFNSKQLERLLQHATVKPVVNQVECHPYLNQKRLKEFCEARGVKITXYSPLGS 750 SNF + +ERL++ V P VNQ+E HP+ Q ++++ G+ I YSP GS Sbjct: 139 SNFTCQHIERLIEDTGVVPAVNQLELHPHFQQCDVRDYHHEAGIAIQSYSPFGS 192 Score = 38.3 bits (85), Expect = 0.26 Identities = 25/70 (35%), Positives = 31/70 (44%) Frame = +3 Query: 138 GASXPVFGXGXWXSKPGXVXXAVKXAIDIGXRHIDCAYVYGNXXXVGXAITSKIKEGVVT 317 G P G G W V ++ A+ G RH D A Y N VG A ++ V Sbjct: 11 GYYMPRPGCGLWLIDNRDVDSLIRQALKAGFRHFDTAQAYFNEDGVGRA----LRYTEVP 66 Query: 318 RXXLFITSKL 347 R LFITSK+ Sbjct: 67 REQLFITSKI 76 >UniRef50_A6RKL9 Cluster: Putative uncharacterized protein; n=3; Sclerotiniaceae|Rep: Putative uncharacterized protein - Botryotinia fuckeliana B05.10 Length = 360 Score = 83.4 bits (197), Expect = 7e-15 Identities = 46/126 (36%), Positives = 75/126 (59%) Frame = +1 Query: 406 NLNVQYLDLYLIHWPQAYKEDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIG 585 +L ++YLDLYLIHWP + +G+ ++D+V T+K+M L K ++ +IG Sbjct: 128 DLGLEYLDLYLIHWPIGFSSNGA------------KNLDHVQTYKSMISLPKSRVL-NIG 174 Query: 586 VSNFNSKQLERLLQHATVKPVVNQVECHPYLNQKRLKEFCEARGVKITXYSPLGSPDRPW 765 VSNF+ QL+ ++ T+ P ++Q+E HPYL Q +A G+K+T YSPLG+ + + Sbjct: 175 VSNFSPLQLKNVVSTGTI-PYMHQMELHPYLQQSAWVATHKALGIKMTAYSPLGNTNPTY 233 Query: 766 GQARRP 783 + P Sbjct: 234 HSSTSP 239 Score = 67.7 bits (158), Expect = 4e-10 Identities = 34/75 (45%), Positives = 41/75 (54%), Gaps = 2/75 (2%) Frame = +3 Query: 144 SXPVFGXGXWXSK--PGXVXXAVKXAIDIGXRHIDCAYVYGNXXXVGXAITSKIKEGVVT 317 S P+ G G W K P AV AI+IG R IDCA VYGN VG I +K + Sbjct: 38 SQPLIGFGTWNLKVSPENTTEAVAYAIEIGYRQIDCAAVYGNEVAVGRGIEEGLKRAGLK 97 Query: 318 RXXLFITSKLWNTFH 362 R +++TSKLWN H Sbjct: 98 REDIWVTSKLWNDHH 112 >UniRef50_Q929C8 Cluster: Lin2349 protein; n=12; Listeria|Rep: Lin2349 protein - Listeria innocua Length = 294 Score = 82.6 bits (195), Expect = 1e-14 Identities = 49/113 (43%), Positives = 61/113 (53%) Frame = +1 Query: 406 NLNVQYLDLYLIHWPQAYKEDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIG 585 NL + YLDLYLIHWP A K Y D+W+AME L E L+KSIG Sbjct: 100 NLKLDYLDLYLIHWPVAGK--------------------YRDSWRAMERLHDEKLIKSIG 139 Query: 586 VSNFNSKQLERLLQHATVKPVVNQVECHPYLNQKRLKEFCEARGVKITXYSPL 744 V+NF L LL A KPV+NQVE HP L Q L+++ + + +SPL Sbjct: 140 VANFKQHHLSDLLVAANEKPVLNQVETHPLLPQNDLRKYLAEQNIAHAAWSPL 192 Score = 45.2 bits (102), Expect = 0.002 Identities = 27/69 (39%), Positives = 37/69 (53%), Gaps = 1/69 (1%) Frame = +3 Query: 150 PVFGXGXWX-SKPGXVXXAVKXAIDIGXRHIDCAYVYGNXXXVGXAITSKIKEGVVTRXX 326 P G G + ++ + AV+ AI++G R D A VY N VG AI + V R Sbjct: 18 PYIGLGVFQVTEQEFIAGAVEKAIEVGYRLFDTAAVYNNEAIVGQAIL----DSAVPREE 73 Query: 327 LFITSKLWN 353 LFI+SK+WN Sbjct: 74 LFISSKVWN 82 >UniRef50_Q03PG5 Cluster: Aldo/keto reductase of diketogulonate reductase family; n=1; Lactobacillus brevis ATCC 367|Rep: Aldo/keto reductase of diketogulonate reductase family - Lactobacillus brevis (strain ATCC 367 / JCM 1170) Length = 268 Score = 82.6 bits (195), Expect = 1e-14 Identities = 45/114 (39%), Positives = 67/114 (58%) Frame = +1 Query: 406 NLNVQYLDLYLIHWPQAYKEDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIG 585 +L + YLDLYLIHWP ++D L +DTW+ +E L ++ V++IG Sbjct: 94 DLQLDYLDLYLIHWPN--EDDFELT---------------LDTWRVLETLYQQKKVRAIG 136 Query: 586 VSNFNSKQLERLLQHATVKPVVNQVECHPYLNQKRLKEFCEARGVKITXYSPLG 747 VSNF+ QL+++ + ATVKP++NQ+E HPY Q L +F + YSP+G Sbjct: 137 VSNFSEDQLKQVFEMATVKPMINQIERHPYKVQADLGQFDTDNDIVNEGYSPIG 190 Score = 67.3 bits (157), Expect = 5e-10 Identities = 35/88 (39%), Positives = 46/88 (52%) Frame = +3 Query: 138 GASXPVFGXGXWXSKPGXVXXAVKXAIDIGXRHIDCAYVYGNXXXVGXAITSKIKEGVVT 317 G + P+ G G + V A+K A+D G RH+DCA++YGN VG A IK + Sbjct: 9 GVTIPMLGFGTYLIDSKDVPAAIKTALDAGYRHLDCAHIYGNEPAVGEA----IKASGID 64 Query: 318 RXXLFITSKLWNTFHRPDLVRGALQEXL 401 R LFITSK+WN D A + L Sbjct: 65 RSDLFITSKVWNADQGYDKTLAAFDQTL 92 Score = 41.1 bits (92), Expect = 0.037 Identities = 15/35 (42%), Positives = 27/35 (77%) Frame = +2 Query: 791 MEDPKLKXIADRLGKTVAQVLIRYQIDXGXIVXPE 895 +EDP + +A++ GK+ AQ+++R+QID G +V P+ Sbjct: 196 LEDPVITKLAEKYGKSPAQIVLRWQIDTGFVVFPK 230 >UniRef50_A7CUW0 Cluster: 2,5-didehydrogluconate reductase; n=6; Bacteria|Rep: 2,5-didehydrogluconate reductase - Opitutaceae bacterium TAV2 Length = 334 Score = 82.6 bits (195), Expect = 1e-14 Identities = 48/113 (42%), Positives = 60/113 (53%) Frame = +1 Query: 409 LNVQYLDLYLIHWPQAYKEDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGV 588 L ++Y+DLYLIHWP KI YVDTWKA+ + +GL +SIGV Sbjct: 153 LQLEYVDLYLIHWPVP--------------KID----RYVDTWKALAKIKADGLARSIGV 194 Query: 589 SNFNSKQLERLLQHATVKPVVNQVECHPYLNQKRLKEFCEARGVKITXYSPLG 747 SNF L+RL + PVVNQVE HP L Q L+ F + +SPLG Sbjct: 195 SNFTPVYLQRLFDETGIVPVVNQVELHPRLQQHELRAFHAKHRIVTEAWSPLG 247 Score = 55.6 bits (128), Expect = 2e-06 Identities = 32/96 (33%), Positives = 45/96 (46%) Frame = +3 Query: 114 IPVVXFXXGASXPVFGXGXWXSKPGXVXXAVKXAIDIGXRHIDCAYVYGNXXXVGXAITS 293 IP + G S P G G W ++ A + G R ID A +YGN VG A Sbjct: 59 IPTLPLSDGTSIPQLGLGVWQMPDDGAGVPIQAAFNAGYRAIDTAPIYGNEEGVGRA--- 115 Query: 294 KIKEGVVTRXXLFITSKLWNTFHRPDLVRGALQEXL 401 I+ + R L+IT+K+WN+ D A++E L Sbjct: 116 -IRASGLPRKELYITTKVWNSAQGYDSTLRAVRESL 150 Score = 35.5 bits (78), Expect = 1.9 Identities = 15/35 (42%), Positives = 23/35 (65%) Frame = +2 Query: 791 MEDPKLKXIADRLGKTVAQVLIRYQIDXGXIVXPE 895 + DP L IA + G++ AQV+IR+ I G +V P+ Sbjct: 252 LADPVLAGIAQKHGRSAAQVIIRWHIQQGLVVIPK 286 >UniRef50_A6WDZ5 Cluster: Aldo/keto reductase; n=5; Bacteria|Rep: Aldo/keto reductase - Kineococcus radiotolerans SRS30216 Length = 343 Score = 82.6 bits (195), Expect = 1e-14 Identities = 42/120 (35%), Positives = 62/120 (51%), Gaps = 1/120 (0%) Frame = +1 Query: 406 NLNVQYLDLYLIHWPQAYKEDGSLFPTDQSGKIQFSDVD-YVDTWKAMEPLVKEGLVKSI 582 +L + +LD +HWP + + + D D Y+ W A+E LV GLV+ + Sbjct: 112 DLRLDHLDAVFVHWPFPNHHPPMADTDARDPRARPYDHDAYLALWGALEGLVDSGLVRHL 171 Query: 583 GVSNFNSKQLERLLQHATVKPVVNQVECHPYLNQKRLKEFCEARGVKITXYSPLGSPDRP 762 G SN +L+ LL+ A + P +N++E HP Q L C G++ YSPLGSP RP Sbjct: 172 GTSNTTVAKLDLLLRDARIPPALNEMELHPCFQQPELFAHCVRHGIQPVGYSPLGSPSRP 231 Score = 63.7 bits (148), Expect = 6e-09 Identities = 35/88 (39%), Positives = 44/88 (50%), Gaps = 3/88 (3%) Frame = +3 Query: 114 IPVVXFXXGASXPVFGXGXWXS---KPGXVXXAVKXAIDIGXRHIDCAYVYGNXXXVGXA 284 +P GA+ P G G + S P V AV A+ G R +DCA VYGN VG A Sbjct: 13 VPRRELRGGATVPAIGIGTFGSDRYSPAEVAAAVAGAVAAGYRLVDCAAVYGNEAQVGEA 72 Query: 285 ITSKIKEGVVTRXXLFITSKLWNTFHRP 368 + + G V R LF+ SK+WN H P Sbjct: 73 LAGAVAGG-VDRDELFVVSKVWNDAHAP 99 >UniRef50_A6QXT4 Cluster: Predicted protein; n=1; Ajellomyces capsulatus NAm1|Rep: Predicted protein - Ajellomyces capsulatus NAm1 Length = 315 Score = 82.6 bits (195), Expect = 1e-14 Identities = 41/113 (36%), Positives = 67/113 (59%) Frame = +1 Query: 409 LNVQYLDLYLIHWPQAYKEDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGV 588 L+V Y+D++L+HWP A DG D+ +V+T+K ME LV +S+GV Sbjct: 67 LDVGYIDIFLLHWPNASGPDGRWRGIDERPT-------FVETYKKMEKLVGPKC-RSLGV 118 Query: 589 SNFNSKQLERLLQHATVKPVVNQVECHPYLNQKRLKEFCEARGVKITXYSPLG 747 + + K ++ LL+ TVKPV+NQ+E HP+ +L +C +G+++ + PLG Sbjct: 119 CSLSQKSMDVLLKECTVKPVINQIEVHPFNPSLKLVPYCLDKGIQVISWGPLG 171 >UniRef50_A6W8E7 Cluster: 2,5-didehydrogluconate reductase; n=3; Actinomycetales|Rep: 2,5-didehydrogluconate reductase - Kineococcus radiotolerans SRS30216 Length = 289 Score = 82.2 bits (194), Expect = 2e-14 Identities = 43/107 (40%), Positives = 57/107 (53%) Frame = +1 Query: 424 LDLYLIHWPQAYKEDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNS 603 +DLYLIHWP PT G D+V TWK +E G ++SIGVSNF Sbjct: 110 IDLYLIHWP---------LPTLYGG-------DFVSTWKVLEEARAAGKLRSIGVSNFQV 153 Query: 604 KQLERLLQHATVKPVVNQVECHPYLNQKRLKEFCEARGVKITXYSPL 744 L+RL Q ATV P VNQ+E HPY + ++ C + + +SP+ Sbjct: 154 NHLQRLAQEATVVPAVNQIEVHPYFGNEEVRRHCGEHQIGVEAWSPI 200 Score = 71.3 bits (167), Expect = 3e-11 Identities = 37/97 (38%), Positives = 50/97 (51%) Frame = +3 Query: 105 APXIPVVXFXXGASXPVFGXGXWXSKPGXVXXAVKXAIDIGXRHIDCAYVYGNXXXVGXA 284 A +P + G P G G + +PG AVK A+D+G RHID A +YGN V Sbjct: 9 AMTVPTILLNDGREIPQLGFGVFQIEPGDTAQAVKTALDLGYRHIDTAQMYGNEAEVAQG 68 Query: 285 ITSKIKEGVVTRXXLFITSKLWNTFHRPDLVRGALQE 395 I + V R +++TSKL N FH PD R A+ + Sbjct: 69 IA----DSGVPRDEIWVTSKLNNGFHEPDAARKAVDD 101 Score = 39.9 bits (89), Expect = 0.086 Identities = 15/35 (42%), Positives = 27/35 (77%) Frame = +2 Query: 791 MEDPKLKXIADRLGKTVAQVLIRYQIDXGXIVXPE 895 ++DP + +A+RLGK+ AQV++R+ ++ G IV P+ Sbjct: 206 LDDPTVTAVANRLGKSPAQVVLRWHVERGDIVFPK 240 >UniRef50_A6NPD6 Cluster: Putative uncharacterized protein; n=3; Bacteria|Rep: Putative uncharacterized protein - Bacteroides capillosus ATCC 29799 Length = 287 Score = 82.2 bits (194), Expect = 2e-14 Identities = 45/113 (39%), Positives = 61/113 (53%) Frame = +1 Query: 409 LNVQYLDLYLIHWPQAYKEDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGV 588 L YLDLYLIHWP+ E D+ +TW+A+E L + GLV++IGV Sbjct: 98 LGTDYLDLYLIHWPRPDLELEDWAKLDR------------ETWRALERLYESGLVRAIGV 145 Query: 589 SNFNSKQLERLLQHATVKPVVNQVECHPYLNQKRLKEFCEARGVKITXYSPLG 747 SNF LE +L A V P+V+Q+E HP Q FC+ + + +SPLG Sbjct: 146 SNFLPHHLEPILASANVAPMVDQLEFHPGYTQDEAVAFCQNHSILVEAWSPLG 198 Score = 43.2 bits (97), Expect = 0.009 Identities = 26/73 (35%), Positives = 33/73 (45%) Frame = +3 Query: 138 GASXPVFGXGXWXSKPGXVXXAVKXAIDIGXRHIDCAYVYGNXXXVGXAITSKIKEGVVT 317 G S P G G + + G + AI G RH D A YG +G A+ E + Sbjct: 13 GLSIPAVGFGTYKTGDGD-SAVLSNAIAQGYRHFDTASFYGTETALGQAVA----ESDIP 67 Query: 318 RXXLFITSKLWNT 356 R F+TSKLW T Sbjct: 68 REDFFLTSKLWKT 80 >UniRef50_Q7N0E4 Cluster: 2,5-diketo-D-gluconic acid reductase A; n=2; Bacteria|Rep: 2,5-diketo-D-gluconic acid reductase A - Photorhabdus luminescens subsp. laumondii Length = 292 Score = 81.8 bits (193), Expect = 2e-14 Identities = 44/112 (39%), Positives = 61/112 (54%) Frame = +1 Query: 409 LNVQYLDLYLIHWPQAYKEDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGV 588 L + Y+DLYLIHWP P DQ YV W+ + L KEGL++SIGV Sbjct: 96 LQLDYVDLYLIHWPAP--------PQDQ----------YVGAWQQLIELQKEGLIRSIGV 137 Query: 589 SNFNSKQLERLLQHATVKPVVNQVECHPYLNQKRLKEFCEARGVKITXYSPL 744 SNF + ++RL+ V PV+NQ+E HP L Q++L + + +SPL Sbjct: 138 SNFQPEHIQRLINETGVHPVINQIELHPLLQQRQLHAWNATHNIVTESWSPL 189 Score = 60.9 bits (141), Expect = 4e-08 Identities = 34/95 (35%), Positives = 46/95 (48%) Frame = +3 Query: 117 PVVXFXXGASXPVFGXGXWXSKPGXVXXAVKXAIDIGXRHIDCAYVYGNXXXVGXAITSK 296 P++ G P G G W S + + A+DIG R ID A +Y N VG A Sbjct: 5 PIIRLADGNHMPQLGLGSWASDDQQIAETIHAALDIGYRAIDTAAIYNNEKGVGNA---- 60 Query: 297 IKEGVVTRXXLFITSKLWNTFHRPDLVRGALQEXL 401 ++E + R +F+T+KLWN H R AL E L Sbjct: 61 LQETDIPREDIFVTTKLWNDRHLD--ARAALTESL 93 Score = 33.1 bits (72), Expect = 9.9 Identities = 14/30 (46%), Positives = 21/30 (70%) Frame = +2 Query: 806 LKXIADRLGKTVAQVLIRYQIDXGXIVXPE 895 ++ + + GKT AQV+IR+ ID G IV P+ Sbjct: 202 VQHLTQKYGKTPAQVVIRWHIDNGMIVIPK 231 >UniRef50_Q2U219 Cluster: Aldo/keto reductase family proteins; n=6; Pezizomycotina|Rep: Aldo/keto reductase family proteins - Aspergillus oryzae Length = 294 Score = 81.8 bits (193), Expect = 2e-14 Identities = 45/112 (40%), Positives = 59/112 (52%) Frame = +1 Query: 409 LNVQYLDLYLIHWPQAYKEDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGV 588 L + Y+DLYLIH P K DG L W AME + + G K+IGV Sbjct: 109 LQLNYVDLYLIHSPFFAKSDGEL----------------QQAWAAMEKVQQAGKAKAIGV 152 Query: 589 SNFNSKQLERLLQHATVKPVVNQVECHPYLNQKRLKEFCEARGVKITXYSPL 744 SN++ LE L+ A + PV+NQ+E HPYL Q+ L F + +KI Y PL Sbjct: 153 SNYHQSHLEATLKTAVIAPVINQIEHHPYLQQEELLRFQREKDIKIASYGPL 204 Score = 45.6 bits (103), Expect = 0.002 Identities = 31/89 (34%), Positives = 42/89 (47%), Gaps = 9/89 (10%) Frame = +3 Query: 108 PXIPVVXFXXGASXPVFGXGX---WXSKPGX------VXXAVKXAIDIGXRHIDCAYVYG 260 P P V S P+ G G W + G + A+K AI +G RH+D A VYG Sbjct: 7 PNTPRVKLNDNVSIPILGYGTGTAWYKQAGDDSVNRELVEAIKTAIRLGYRHLDGAEVYG 66 Query: 261 NXXXVGXAITSKIKEGVVTRXXLFITSKL 347 +G A IKE + R LF+T+K+ Sbjct: 67 TEAELGVA----IKESGIPREELFVTTKV 91 >UniRef50_A5ZYE6 Cluster: Putative uncharacterized protein; n=1; Ruminococcus obeum ATCC 29174|Rep: Putative uncharacterized protein - Ruminococcus obeum ATCC 29174 Length = 263 Score = 81.4 bits (192), Expect = 3e-14 Identities = 43/112 (38%), Positives = 62/112 (55%) Frame = +1 Query: 409 LNVQYLDLYLIHWPQAYKEDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGV 588 L + Y+DLYLIHWP G +++TWK ME +++ G SIGV Sbjct: 85 LGLDYIDLYLIHWPVP----GC----------------FLNTWKDMEKILESGRALSIGV 124 Query: 589 SNFNSKQLERLLQHATVKPVVNQVECHPYLNQKRLKEFCEARGVKITXYSPL 744 SNF + LE L + + + P VNQ+ECHP K L E+C+A +++ Y+PL Sbjct: 125 SNFEIRHLEELRRVSGIVPAVNQIECHPLCYPKELIEYCQANDIQVQAYAPL 176 Score = 43.6 bits (98), Expect = 0.007 Identities = 31/85 (36%), Positives = 39/85 (45%), Gaps = 1/85 (1%) Frame = +3 Query: 150 PVFGXGXWXSKPGX-VXXAVKXAIDIGXRHIDCAYVYGNXXXVGXAITSKIKEGVVTRXX 326 P+ G G + + A+ A+ G R +D A Y N VG I K GV R Sbjct: 2 PLLGLGLYKTTDAVEAEDAIAAAVQNGYRLLDTASAYKNEEFVGCGIA---KCGV-PRKD 57 Query: 327 LFITSKLWNTFHRPDLVRGALQEXL 401 LFIT+K+WN R V GA Q L Sbjct: 58 LFITTKIWNNAQRLGDVEGAFQRSL 82 >UniRef50_A5VK30 Cluster: 2,5-didehydrogluconate reductase; n=2; Lactobacillus reuteri|Rep: 2,5-didehydrogluconate reductase - Lactobacillus reuteri F275 Length = 300 Score = 81.4 bits (192), Expect = 3e-14 Identities = 39/114 (34%), Positives = 65/114 (57%) Frame = +1 Query: 409 LNVQYLDLYLIHWPQAYKEDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGV 588 L Y+DL L+HWP K Y ++W+A+E + K+G K+IGV Sbjct: 109 LQTNYVDLLLLHWPVNDK--------------------YNESWRALEDIYKDGQAKAIGV 148 Query: 589 SNFNSKQLERLLQHATVKPVVNQVECHPYLNQKRLKEFCEARGVKITXYSPLGS 750 NFN +++ LL HA +KP +NQ+E +P ++Q ++ +FC +++ +SPLG+ Sbjct: 149 CNFNVERMTDLLDHAKIKPAINQIEFNPLIHQPKIVKFCRENDIQLEAWSPLGN 202 Score = 41.1 bits (92), Expect = 0.037 Identities = 30/96 (31%), Positives = 39/96 (40%), Gaps = 1/96 (1%) Frame = +3 Query: 117 PVVXFXXGASXPVFGXGXWXSKPGXVXXAVKXAIDIGXRHIDCAYVYGNXXXVGXAITSK 296 P + G P G G W + VK AI ID A YGN VG I Sbjct: 11 PKIKLNNGHLIPQLGLGVWKASLAETQQMVKEAIMNDYVLIDTAKQYGNEAAVGQGIQDG 70 Query: 297 IKEGVVTRXXLFITSKLWNTFHRP-DLVRGALQEXL 401 K R +F+T+K++N D +R A+ E L Sbjct: 71 FKATGRKRDSIFLTTKIFNGDQGDYDKLRQAVNEQL 106 >UniRef50_A0JRJ6 Cluster: Aldo/keto reductase; n=2; Micrococcineae|Rep: Aldo/keto reductase - Arthrobacter sp. (strain FB24) Length = 281 Score = 81.4 bits (192), Expect = 3e-14 Identities = 46/113 (40%), Positives = 58/113 (51%) Frame = +1 Query: 409 LNVQYLDLYLIHWPQAYKEDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGV 588 L V+++DLYLIHWP S Y + WKAME L +++IGV Sbjct: 101 LGVEFVDLYLIHWPVP------------------SQGLYTEAWKAMEKLYANSQIRAIGV 142 Query: 589 SNFNSKQLERLLQHATVKPVVNQVECHPYLNQKRLKEFCEARGVKITXYSPLG 747 SNF + L+ LL A V P VNQVE HP Q+ L C G+ + YSPLG Sbjct: 143 SNFLGEHLDTLLPAADVVPAVNQVEIHPTFQQQELAAKCRELGIAVEAYSPLG 195 >UniRef50_Q235V6 Cluster: Oxidoreductase, aldo/keto reductase family protein; n=2; Tetrahymena thermophila SB210|Rep: Oxidoreductase, aldo/keto reductase family protein - Tetrahymena thermophila SB210 Length = 332 Score = 81.4 bits (192), Expect = 3e-14 Identities = 44/112 (39%), Positives = 62/112 (55%) Frame = +1 Query: 409 LNVQYLDLYLIHWPQAYKEDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGV 588 L + Y+DLY +H+P + + K +F + W +E + GL KSIGV Sbjct: 102 LQLDYVDLYYLHFPLGFLSE----------KEEFVHLPVHVAWAQLEEAHRLGLAKSIGV 151 Query: 589 SNFNSKQLERLLQHATVKPVVNQVECHPYLNQKRLKEFCEARGVKITXYSPL 744 SNFN L LL +A VKPV NQVE ++ QK L +FC+ G+ +T Y+PL Sbjct: 152 SNFNVMALADLLSYAKVKPVSNQVEVSVFIQQKNLIKFCQRFGIHVTAYAPL 203 Score = 45.2 bits (102), Expect = 0.002 Identities = 24/72 (33%), Positives = 38/72 (52%), Gaps = 1/72 (1%) Frame = +3 Query: 138 GASXPVFGXGXWX-SKPGXVXXAVKXAIDIGXRHIDCAYVYGNXXXVGXAITSKIKEGVV 314 G P+ G G + + + ++ A+D G RHID A Y N +G ++ + KEG Sbjct: 13 GQIMPLVGLGTYLLNSKEEMTNLLRTALDAGYRHIDTAVNYQNEAMIGESLKTIFKEGKY 72 Query: 315 TRXXLFITSKLW 350 +R LFI SK++ Sbjct: 73 SRKDLFIVSKVF 84 >UniRef50_O13848 Cluster: NADH/NADPH dependent indole-3-acetaldehyde reductase AKR3C2; n=1; Schizosaccharomyces pombe|Rep: NADH/NADPH dependent indole-3-acetaldehyde reductase AKR3C2 - Schizosaccharomyces pombe (Fission yeast) Length = 284 Score = 81.4 bits (192), Expect = 3e-14 Identities = 49/114 (42%), Positives = 63/114 (55%), Gaps = 2/114 (1%) Frame = +1 Query: 409 LNVQYLDLYLIHWPQAYKEDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGV 588 L YLDLYL+H P + E KI S+ WKAME + GLV S+GV Sbjct: 98 LGTDYLDLYLLHSPIPFYEK----------KIPISE-----GWKAMETALGTGLVHSVGV 142 Query: 589 SNFNSKQLERLLQHATVKPVVNQVECHP--YLNQKRLKEFCEARGVKITXYSPL 744 SNF LE LL+ +T+ P VNQ+E HP Y K L EFC+++G+ + Y PL Sbjct: 143 SNFRIPDLEELLKTSTITPRVNQIEFHPQVYKAAKPLVEFCQSKGIIVEGYGPL 196 Score = 52.4 bits (120), Expect = 2e-05 Identities = 41/104 (39%), Positives = 49/104 (47%) Frame = +3 Query: 90 LINKMAPXIPVVXFXXGASXPVFGXGXWXSKPGXVXXAVKXAIDIGXRHIDCAYVYGNXX 269 LI M P IPV + G + G + +VK A+ G HIDCA VYGN Sbjct: 2 LIAAMGPKIPVPAYGVGTALFKKEKGEINRT---IVDSVKNALAAGFIHIDCAEVYGNEE 58 Query: 270 XVGXAITSKIKEGVVTRXXLFITSKLWNTFHRPDLVRGALQEXL 401 VG A +KE V R LFITSK+ H D + AL E L Sbjct: 59 EVGVA----LKEANVPRSKLFITSKV---MHNVDNIPEALNESL 95 >UniRef50_A5AD50 Cluster: Putative uncharacterized protein; n=3; Magnoliophyta|Rep: Putative uncharacterized protein - Vitis vinifera (Grape) Length = 304 Score = 81.0 bits (191), Expect = 4e-14 Identities = 40/85 (47%), Positives = 46/85 (54%) Frame = +3 Query: 102 MAPXIPVVXFXXGASXPVFGXGXWXSKPGXVXXAVKXAIDIGXRHIDCAYVYGNXXXVGX 281 M+ I GA P G G W S PG V AV AI +G RHIDCA VYGN +G Sbjct: 1 MSDDIRFFQLNTGAKMPSVGLGTWQSDPGLVGQAVAIAIKVGYRHIDCAQVYGNEEEIGI 60 Query: 282 AITSKIKEGVVTRXXLFITSKLWNT 356 + +GVV R L+ITSKLW T Sbjct: 61 VLKKLFDDGVVKREDLWITSKLWCT 85 Score = 58.4 bits (135), Expect = 2e-07 Identities = 29/57 (50%), Positives = 36/57 (63%), Gaps = 1/57 (1%) Frame = +1 Query: 598 NSKQLERL-LQHATVKPVVNQVECHPYLNQKRLKEFCEARGVKITXYSPLGSPDRPW 765 +S L RL L A V P V QVECHP Q +L FC+++GV +T +SPLGSP W Sbjct: 141 HSMILARLELLVARVPPAVIQVECHPSWQQSKLHAFCKSKGVHLTGFSPLGSPGTTW 197 >UniRef50_Q17568 Cluster: Putative uncharacterized protein; n=1; Caenorhabditis elegans|Rep: Putative uncharacterized protein - Caenorhabditis elegans Length = 287 Score = 81.0 bits (191), Expect = 4e-14 Identities = 40/113 (35%), Positives = 64/113 (56%) Frame = +1 Query: 409 LNVQYLDLYLIHWPQAYKEDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGV 588 L+ +YLDL L+H+P+ P D + + + DTW A+E L EG ++SIGV Sbjct: 99 LDRKYLDLVLVHYPR---------PLDTEDLNENNKMYRKDTWIALEKLHAEGKIRSIGV 149 Query: 589 SNFNSKQLERLLQHATVKPVVNQVECHPYLNQKRLKEFCEARGVKITXYSPLG 747 SN+ +E + + T++P VNQ+E HP+ +K L+ +C + +SPLG Sbjct: 150 SNYEPHHIEEMRSYITIEPQVNQIEYHPHFQRKVLRAYCNKNEILFQAFSPLG 202 >UniRef50_Q00XM4 Cluster: Aldo/keto reductase family proteins; n=2; Ostreococcus|Rep: Aldo/keto reductase family proteins - Ostreococcus tauri Length = 336 Score = 80.6 bits (190), Expect = 5e-14 Identities = 45/107 (42%), Positives = 58/107 (54%) Frame = +1 Query: 427 DLYLIHWPQAYKEDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSK 606 DL L+HWP KE P + + D TW+A+E +K G ++IGVSN+ Sbjct: 152 DLVLVHWPGRDKES----PDSERHR----DARRW-TWRALENALKMGQCRAIGVSNYELS 202 Query: 607 QLERLLQHATVKPVVNQVECHPYLNQKRLKEFCEARGVKITXYSPLG 747 L LLQ VKP VNQ+E H Q L+ FCE+ GV + YSPLG Sbjct: 203 HLRELLQFCDVKPAVNQIELHARFPQTELRAFCESVGVHVVGYSPLG 249 Score = 44.0 bits (99), Expect = 0.005 Identities = 34/116 (29%), Positives = 52/116 (44%) Frame = +3 Query: 138 GASXPVFGXGXWXSKPGXVXXAVKXAIDIGXRHIDCAYVYGNXXXVGXAITSKIKEGVVT 317 G + P+ G + + AV+ A+ G +H+D A VYGN VG A+ + +E Sbjct: 59 GITMPMLAFGTYRLRGETCRDAVRDALRCGFQHVDTASVYGNERDVGEALRACHRE---V 115 Query: 318 RXXLFITSKLWNTFHRPDLVRGALQEXLXQSERSVLGSVPDTLAPGLQGRRLSLPD 485 +F+TSK+ + R + A +ER LG PD + GR PD Sbjct: 116 SERIFVTSKIAPSEMRSE--EEAAAAIAGVNER--LGRTPDLVLVHWPGRDKESPD 167 >UniRef50_Q7M4N1 Cluster: Dihydrodiol dehydrogenase DD2; n=2; Homo sapiens|Rep: Dihydrodiol dehydrogenase DD2 - Homo sapiens (Human) Length = 188 Score = 80.6 bits (190), Expect = 5e-14 Identities = 46/99 (46%), Positives = 58/99 (58%), Gaps = 3/99 (3%) Frame = +1 Query: 499 KIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQHATVK--PVVNQVECHP 672 +I F VD TW+AME KSIGVSNFN + LE +L +K PV NQVECHP Sbjct: 55 EILFDTVDLCATWEAME--------KSIGVSNFNHRLLEMILNKPGLKYKPVCNQVECHP 106 Query: 673 YLNQKRLKEFCEARGVKITXYSPLGS-PDRPWGQARRPP 786 Y NQ++L +FC + + + YS LGS + PW R P Sbjct: 107 YFNQRKLLDFC--KDIVLVAYSALGSHREEPWVDPNRTP 143 Score = 57.6 bits (133), Expect = 4e-07 Identities = 30/60 (50%), Positives = 37/60 (61%) Frame = +3 Query: 213 AIDIGXRHIDCAYVYGNXXXVGXAITSKIKEGVVTRXXLFITSKLWNTFHRPDLVRGALQ 392 AI+ G HID A+VY N VG A +G V R +F TSKLW+ HRP+LVR AL+ Sbjct: 2 AIEAGFHHIDSAHVYNNEEQVGIA------DGSVKREDIFYTSKLWSNSHRPELVRPALE 55 >UniRef50_O14088 Cluster: Xylose and arabinose reductase; n=1; Schizosaccharomyces pombe|Rep: Xylose and arabinose reductase - Schizosaccharomyces pombe (Fission yeast) Length = 275 Score = 80.6 bits (190), Expect = 5e-14 Identities = 31/76 (40%), Positives = 56/76 (73%), Gaps = 1/76 (1%) Frame = +1 Query: 520 DYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQ-HATVKPVVNQVECHPYLNQKRLK 696 D +++WKA+E V+EG +++IGVSNF ++ LL H + P VNQ+E HP+ +Q+++ Sbjct: 116 DRIESWKALEKGVEEGKLRAIGVSNFGPHHIQELLDSHPKIIPCVNQIELHPFCSQQKVV 175 Query: 697 EFCEARGVKITXYSPL 744 ++CE++G+++ Y+PL Sbjct: 176 DYCESKGIQLAAYAPL 191 Score = 40.3 bits (90), Expect = 0.065 Identities = 24/75 (32%), Positives = 32/75 (42%) Frame = +3 Query: 123 VXFXXGASXPVFGXGXWXSKPGXVXXAVKXAIDIGXRHIDCAYVYGNXXXVGXAITSKIK 302 V G P F G + +V A+ G RHID A +Y N G AI ++ Sbjct: 6 VKLNNGLKCPQFAYGSYMVNRTKCFDSVYAALQCGYRHIDSAQMYHNEADCGRAILKFME 65 Query: 303 EGVVTRXXLFITSKL 347 E R ++ TSKL Sbjct: 66 ETGTKREDIWFTSKL 80 >UniRef50_Q5FKI1 Cluster: Reductase-dehydrogenase; n=1; Lactobacillus acidophilus|Rep: Reductase-dehydrogenase - Lactobacillus acidophilus Length = 271 Score = 80.2 bits (189), Expect = 7e-14 Identities = 42/110 (38%), Positives = 61/110 (55%) Frame = +1 Query: 415 VQYLDLYLIHWPQAYKEDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSN 594 ++Y+DL LIH PQ + E G ++ W+AME VK G V+SIGVSN Sbjct: 100 LEYIDLLLIHSPQPWIEVNRTNDRHFKGNLE--------NWRAMEEAVKAGKVRSIGVSN 151 Query: 595 FNSKQLERLLQHATVKPVVNQVECHPYLNQKRLKEFCEARGVKITXYSPL 744 F + +E ++ + T+ P VNQ+E H L ++C+ G+KI YSPL Sbjct: 152 FLQEDIENIVNNGTITPAVNQIEVHIGKVPVELMDYCKKLGIKIEAYSPL 201 Score = 38.3 bits (85), Expect = 0.26 Identities = 24/75 (32%), Positives = 32/75 (42%) Frame = +3 Query: 123 VXFXXGASXPVFGXGXWXSKPGXVXXAVKXAIDIGXRHIDCAYVYGNXXXVGXAITSKIK 302 V G P G W V V+ A++IG R D A YGN VG I + Sbjct: 7 VILNNGEKIPQIQLGTWLINNDEVNKVVRQAVNIGYRGFDTAKDYGNESGVGKGIWN--- 63 Query: 303 EGVVTRXXLFITSKL 347 + R +F+T+KL Sbjct: 64 -SDIERSDIFLTTKL 77 >UniRef50_Q03U37 Cluster: Aldo/keto reductase of diketogulonate reductase family; n=5; Lactobacillus|Rep: Aldo/keto reductase of diketogulonate reductase family - Lactobacillus brevis (strain ATCC 367 / JCM 1170) Length = 282 Score = 80.2 bits (189), Expect = 7e-14 Identities = 48/113 (42%), Positives = 60/113 (53%) Frame = +1 Query: 409 LNVQYLDLYLIHWPQAYKEDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGV 588 L YLDL LIHWP +E + DTW+A+E L +G VKSIGV Sbjct: 102 LQTDYLDLLLIHWP--VREH------------------FFDTWRALEQLKADGQVKSIGV 141 Query: 589 SNFNSKQLERLLQHATVKPVVNQVECHPYLNQKRLKEFCEARGVKITXYSPLG 747 SN+ LE L A PVVNQVE HPYLNQ+ L ++ + + +SPLG Sbjct: 142 SNYTIAHLELLATKAKEMPVVNQVEYHPYLNQQALADYDQEHDIVTEAWSPLG 194 >UniRef50_Q54NR2 Cluster: Aldo-keto reductase; n=3; Dictyostelium discoideum AX4|Rep: Aldo-keto reductase - Dictyostelium discoideum AX4 Length = 305 Score = 80.2 bits (189), Expect = 7e-14 Identities = 47/114 (41%), Positives = 61/114 (53%), Gaps = 2/114 (1%) Frame = +1 Query: 409 LNVQYLDLYLIHWPQAYKEDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGV 588 L + YLD YLIHWP DGS D IQ + TW+A+E L ++ V+SIGV Sbjct: 118 LQLDYLDCYLIHWPGVKGLDGS----DSGNSIQRAQ-----TWRALEKLYQDKKVRSIGV 168 Query: 589 SNFNSKQLERLLQ--HATVKPVVNQVECHPYLNQKRLKEFCEARGVKITXYSPL 744 SN+ L LL + +KP +NQVE HP QK L EFC+ + + Y L Sbjct: 169 SNYTINHLTELLSSPNLQIKPAINQVEFHPLNFQKDLLEFCKNNKIILESYGSL 222 >UniRef50_Q890A0 Cluster: Oxidoreductase; n=6; Lactobacillales|Rep: Oxidoreductase - Lactobacillus plantarum Length = 282 Score = 79.8 bits (188), Expect = 9e-14 Identities = 45/126 (35%), Positives = 70/126 (55%), Gaps = 3/126 (2%) Frame = +1 Query: 406 NLNVQYLDLYLIHWPQAYKEDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIG 585 NL + Y+DLYL+H P +P Q G++ D +D W+AME + + G K+IG Sbjct: 99 NLGLDYVDLYLVHAP---------WPWGQVGRVY--DEANLDVWQAMEAIYQSGRAKAIG 147 Query: 586 VSNFNSKQLERLLQHATVKPVVNQVECHPYLNQKRLKEFCEARGVKITXYSPL---GSPD 756 VSNF + L+ +L AT+ P+VNQ++ + + ++ +F E + + YSPL G D Sbjct: 148 VSNFAVRDLKNILNQATIPPMVNQIQYYLGFTEPKITKFSEEHAMLVEAYSPLATGGVLD 207 Query: 757 RPWGQA 774 P QA Sbjct: 208 NPQVQA 213 >UniRef50_Q6F7K7 Cluster: 2,5-diketo-D-gluconate reductase; n=20; Bacteria|Rep: 2,5-diketo-D-gluconate reductase - Acinetobacter sp. (strain ADP1) Length = 297 Score = 79.8 bits (188), Expect = 9e-14 Identities = 44/113 (38%), Positives = 61/113 (53%) Frame = +1 Query: 409 LNVQYLDLYLIHWPQAYKEDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGV 588 + YLDLYLIHWP Q G Y++ W+A+ K+G ++SIGV Sbjct: 116 MQFDYLDLYLIHWPNP-----------QQGL-------YIEAWQALIDAQKKGYIRSIGV 157 Query: 589 SNFNSKQLERLLQHATVKPVVNQVECHPYLNQKRLKEFCEARGVKITXYSPLG 747 SNF K +E L + V PV+NQVE HPY NQ + + E++ + +SPLG Sbjct: 158 SNFLPKHIETLRRETGVIPVINQVELHPYFNQAEQRAYDESQQIITMAWSPLG 210 Score = 42.7 bits (96), Expect = 0.012 Identities = 29/100 (29%), Positives = 44/100 (44%) Frame = +3 Query: 114 IPVVXFXXGASXPVFGXGXWXSKPGXVXXAVKXAIDIGXRHIDCAYVYGNXXXVGXAITS 293 IP + G S P G G + K + A+ G R +D A+ Y N VG A+ Sbjct: 22 IPDLILHDGHSIPALGFGTYTLKGQQGVDTMLRALGHGYRMLDSAFNYENEGAVGAAV-- 79 Query: 294 KIKEGVVTRXXLFITSKLWNTFHRPDLVRGALQEXLXQSE 413 ++ + R +FITSKL H D ++E L + + Sbjct: 80 --RQSGLLRDEIFITSKLPGRHHAYDKAMETIEESLYRMQ 117 >UniRef50_Q7XY49 Cluster: Mannose 6-phosphate reductase; n=1; Griffithsia japonica|Rep: Mannose 6-phosphate reductase - Griffithsia japonica (Red alga) Length = 174 Score = 79.8 bits (188), Expect = 9e-14 Identities = 41/88 (46%), Positives = 49/88 (55%) Frame = +3 Query: 138 GASXPVFGXGXWXSKPGXVXXAVKXAIDIGXRHIDCAYVYGNXXXVGXAITSKIKEGVVT 317 GA P+ G G W + AV A+ G RHIDCA VY N VG AI+ I GVV Sbjct: 11 GAKMPLNGFGTWKASVEETEQAVTAALRAGYRHIDCAAVYWNEAAVGTAISKAISGGVVK 70 Query: 318 RXXLFITSKLWNTFHRPDLVRGALQEXL 401 R LFITSK+WNT H D V + ++ L Sbjct: 71 REDLFITSKVWNTCHATDKVVDSCRQSL 98 Score = 48.0 bits (109), Expect = 3e-04 Identities = 27/68 (39%), Positives = 39/68 (57%) Frame = +1 Query: 568 LVKSIGVSNFNSKQLERLLQHATVKPVVNQVECHPYLNQKRLKEFCEARGVKITXYSPLG 747 LV+ IGVSN++ L L +A +KP VNQ E H Y + +L++ C GV + +P Sbjct: 110 LVRDIGVSNYSVALLVDTLNYARIKPSVNQCEAHVYFARPQLRDVCREFGVHLPC-TP-- 166 Query: 748 SPDRPWGQ 771 S RP G+ Sbjct: 167 SSQRPKGR 174 >UniRef50_A7TLC4 Cluster: Putative uncharacterized protein; n=1; Vanderwaltozyma polyspora DSM 70294|Rep: Putative uncharacterized protein - Vanderwaltozyma polyspora DSM 70294 Length = 313 Score = 79.8 bits (188), Expect = 9e-14 Identities = 45/115 (39%), Positives = 64/115 (55%), Gaps = 2/115 (1%) Frame = +1 Query: 409 LNVQYLDLYLIHWPQAYKEDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGV 588 L + Y+DLYLIH P F + G + V WK ME L KEG KSIGV Sbjct: 111 LGLDYVDLYLIHSP--------FFDPEFKGSLTLEKV-----WKDMETLYKEGKAKSIGV 157 Query: 589 SNFNSKQLERLLQHATVKPVVNQVECHPYLNQKR--LKEFCEARGVKITXYSPLG 747 SNF+ K +E +L+ A +KP VNQ+E + +L + + +C+ +++ YSPLG Sbjct: 158 SNFSVKNIEEILKIAGIKPQVNQIEFNAFLQNQTPGIVNYCQKNNIQLEAYSPLG 212 >UniRef50_A7D761 Cluster: Aldo/keto reductase; n=2; Halobacteriaceae|Rep: Aldo/keto reductase - Halorubrum lacusprofundi ATCC 49239 Length = 665 Score = 79.8 bits (188), Expect = 9e-14 Identities = 40/137 (29%), Positives = 65/137 (47%), Gaps = 15/137 (10%) Frame = +1 Query: 388 CRXPWXNLNVQYLDLYLIHWPQAYKEDGSL---------------FPTDQSGKIQFSDVD 522 C L + D Y +HWP A + G L FP + G+ +DV Sbjct: 456 CAGSREELGIDAFDCYALHWPSALEHRGELNRLAEKPVERQETLTFPEGEDGEPATADVA 515 Query: 523 YVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQHATVKPVVNQVECHPYLNQKRLKEF 702 W+ +E + + G +++G+ N + QLE +L+ + P + QVE HPY + L E Sbjct: 516 LATAWRNLEAVHERGWARTLGICNVSRAQLETVLETGEIDPALVQVERHPYRPRNGLVEL 575 Query: 703 CEARGVKITXYSPLGSP 753 C RG+++ +SPL +P Sbjct: 576 CHGRGIRVVAHSPLSAP 592 Score = 37.9 bits (84), Expect = 0.35 Identities = 18/55 (32%), Positives = 28/55 (50%) Frame = +3 Query: 201 AVKXAIDIGXRHIDCAYVYGNXXXVGXAITSKIKEGVVTRXXLFITSKLWNTFHR 365 ++ A+D G R +D A +YGN +G + + G R +F+ K W T HR Sbjct: 397 SIATALDAGYRLLDSAELYGNEHRIGELLAA---PGAPDRERVFLLGKAWRTNHR 448 >UniRef50_A7ALH6 Cluster: Putative uncharacterized protein; n=1; Parabacteroides merdae ATCC 43184|Rep: Putative uncharacterized protein - Parabacteroides merdae ATCC 43184 Length = 301 Score = 78.6 bits (185), Expect = 2e-13 Identities = 41/114 (35%), Positives = 64/114 (56%) Frame = +1 Query: 406 NLNVQYLDLYLIHWPQAYKEDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIG 585 +L Y+DL LIHWP G I+ +TW+ +E V +G ++SIG Sbjct: 121 DLGTDYIDLVLIHWPV-------------KGHIK-------ETWQILEEYVDKGKIRSIG 160 Query: 586 VSNFNSKQLERLLQHATVKPVVNQVECHPYLNQKRLKEFCEARGVKITXYSPLG 747 VSNFN L+ LL++A ++PVVNQ+E PY+ Q + + +G+++ + PLG Sbjct: 161 VSNFNPHHLDELLEYARIRPVVNQIEIEPYMTQHDVVGYTFRKGIQVEAWGPLG 214 Score = 33.5 bits (73), Expect = 7.5 Identities = 13/34 (38%), Positives = 22/34 (64%) Frame = +2 Query: 791 MEDPKLKXIADRLGKTVAQVLIRYQIDXGXIVXP 892 ++DP + IA R GK+ AQV++R+ + G + P Sbjct: 221 LDDPAIGEIAARHGKSAAQVILRWHMQRGLVTIP 254 >UniRef50_Q8F1G4 Cluster: Aldehyde reductase; n=8; Bacteria|Rep: Aldehyde reductase - Leptospira interrogans Length = 278 Score = 77.8 bits (183), Expect = 4e-13 Identities = 42/112 (37%), Positives = 62/112 (55%) Frame = +1 Query: 409 LNVQYLDLYLIHWPQAYKEDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGV 588 L + ++DLYLIH+P K +D+WK +E L + L K+IGV Sbjct: 104 LGIDFVDLYLIHFPVTSKR--------------------MDSWKELEKLYHDKLCKAIGV 143 Query: 589 SNFNSKQLERLLQHATVKPVVNQVECHPYLNQKRLKEFCEARGVKITXYSPL 744 SN+ L LL+++ + P VNQVE HP+LNQ L E+C+ +++ YSPL Sbjct: 144 SNYTIIHLTELLKNSQITPAVNQVEFHPFLNQIHLLEYCKKHKIQLEAYSPL 195 Score = 69.7 bits (163), Expect = 9e-11 Identities = 40/103 (38%), Positives = 51/103 (49%), Gaps = 1/103 (0%) Frame = +3 Query: 96 NKMAPXIPVVXFXXGASXPVFGXGXWXSKPGX-VXXAVKXAIDIGXRHIDCAYVYGNXXX 272 NK P + G S P+ G G W +K G AV A++ G RHID A +Y N Sbjct: 3 NKENPLKQTIMLNNGISMPILGLGVWKTKSGKECKEAVLNALEAGYRHIDTARIYDNEVD 62 Query: 273 VGXAITSKIKEGVVTRXXLFITSKLWNTFHRPDLVRGALQEXL 401 VG AI +E + R +FIT+KLWN D R AL+ L Sbjct: 63 VGQAI----RESGIPRKEIFITTKLWNADQGSDKTRKALENSL 101 Score = 36.3 bits (80), Expect = 1.1 Identities = 16/37 (43%), Positives = 24/37 (64%) Frame = +2 Query: 785 QXMEDPKLKXIADRLGKTVAQVLIRYQIDXGXIVXPE 895 Q +EDP + IA + KT AQ+LIR+ I+ +V P+ Sbjct: 199 QKIEDPTIAKIAQKYDKTPAQILIRWAIEQKIVVIPK 235 >UniRef50_A6LZ55 Cluster: 2,5-didehydrogluconate reductase; n=1; Clostridium beijerinckii NCIMB 8052|Rep: 2,5-didehydrogluconate reductase - Clostridium beijerinckii NCIMB 8052 Length = 289 Score = 77.8 bits (183), Expect = 4e-13 Identities = 40/117 (34%), Positives = 64/117 (54%) Frame = +1 Query: 409 LNVQYLDLYLIHWPQAYKEDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGV 588 LNV+YLD+YLIH+ +Y Y++TW AME L +G +K IGV Sbjct: 100 LNVEYLDMYLIHFASSY---------------------YLETWHAMEELYLQGKIKVIGV 138 Query: 589 SNFNSKQLERLLQHATVKPVVNQVECHPYLNQKRLKEFCEARGVKITXYSPLGSPDR 759 +NF + LE L++H+ + P++NQ+E HP Q L ++ + ++PLG ++ Sbjct: 139 ANFQIQHLEELMKHSRITPMINQIETHPEFPQNELHQYLTKHKILHEAWAPLGQGNK 195 Score = 54.4 bits (125), Expect = 4e-06 Identities = 32/87 (36%), Positives = 43/87 (49%), Gaps = 1/87 (1%) Frame = +3 Query: 138 GASXPVFGXGXWXSKPGX-VXXAVKXAIDIGXRHIDCAYVYGNXXXVGXAITSKIKEGVV 314 G P G G + G AV AI IG RH D A +YGN +G A I++ + Sbjct: 13 GIKIPQVGFGVYKLNKGEDFETAVGEAIKIGYRHFDTAKIYGNEKDLGLA----IEKSQI 68 Query: 315 TRXXLFITSKLWNTFHRPDLVRGALQE 395 R FITSK+WNT H + + A ++ Sbjct: 69 PREEFFITSKVWNTDHGYEATKKAFEQ 95 Score = 34.7 bits (76), Expect = 3.3 Identities = 16/35 (45%), Positives = 23/35 (65%) Frame = +2 Query: 791 MEDPKLKXIADRLGKTVAQVLIRYQIDXGXIVXPE 895 +E+ LK IA KTVAQV++R+ I G I+ P+ Sbjct: 198 LENTVLKKIASNHEKTVAQVILRWHIQRGIIIIPK 232 >UniRef50_A2RMU6 Cluster: Oxidoreductase, aldo/keto reductase family; n=3; Lactococcus lactis|Rep: Oxidoreductase, aldo/keto reductase family - Lactococcus lactis subsp. cremoris (strain MG1363) Length = 281 Score = 77.8 bits (183), Expect = 4e-13 Identities = 38/80 (47%), Positives = 49/80 (61%) Frame = +1 Query: 520 DYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQHATVKPVVNQVECHPYLNQKRLKE 699 +Y W A+E VK G VKSIG+SNF+ ++L L A +KP QVE HPY QK L+E Sbjct: 111 NYRKAWIALENAVKSGKVKSIGISNFDGERLVDLFNFADIKPSALQVETHPYHQQKELQE 170 Query: 700 FCEARGVKITXYSPLGSPDR 759 F + G KI + PLG D+ Sbjct: 171 FLKPYGTKIESWYPLGHGDQ 190 Score = 45.6 bits (103), Expect = 0.002 Identities = 30/72 (41%), Positives = 37/72 (51%), Gaps = 1/72 (1%) Frame = +3 Query: 138 GASXPVFGXGXWXSKPGXVXX-AVKXAIDIGXRHIDCAYVYGNXXXVGXAITSKIKEGVV 314 G P FG G + G AVK A+ +G RHID A+ Y N VG AI S G+ Sbjct: 10 GNIIPQFGLGVYQIPEGEATENAVKEALRLGYRHIDTAHAYQNERSVGRAIHS---SGIP 66 Query: 315 TRXXLFITSKLW 350 ++ITSKLW Sbjct: 67 I-SEIWITSKLW 77 Score = 39.5 bits (88), Expect = 0.11 Identities = 16/38 (42%), Positives = 26/38 (68%) Frame = +2 Query: 779 DPQXMEDPKLKXIADRLGKTVAQVLIRYQIDXGXIVXP 892 D + +++ +LK IA + KTVAQ+++R+ I G IV P Sbjct: 189 DQRLLDESRLKKIAQKYNKTVAQIILRWHIQEGIIVFP 226 >UniRef50_Q5BLA6 Cluster: Zgc:110782; n=2; Danio rerio|Rep: Zgc:110782 - Danio rerio (Zebrafish) (Brachydanio rerio) Length = 287 Score = 77.4 bits (182), Expect = 5e-13 Identities = 44/120 (36%), Positives = 61/120 (50%) Frame = +1 Query: 388 CRXPWXNLNVQYLDLYLIHWPQAYKEDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEG 567 C L+ +Y+DLYLIHWP +G L P D + S+ +W +E G Sbjct: 94 CLRSLEQLDCEYIDLYLIHWPGM---EG-LDPEDS----RHSEYR-AQSWATLEEFHASG 144 Query: 568 LVKSIGVSNFNSKQLERLLQHATVKPVVNQVECHPYLNQKRLKEFCEARGVKITXYSPLG 747 K+IGVSN+ +K + LL V P V Q+EC P L Q+ L++ C G+ YS LG Sbjct: 145 QFKAIGVSNYTAKHIRELLASCRVPPAVLQIECQPKLIQRELRDLCMETGIHFQAYSSLG 204 Score = 39.9 bits (89), Expect = 0.086 Identities = 26/94 (27%), Positives = 41/94 (43%), Gaps = 1/94 (1%) Frame = +3 Query: 114 IPVVXFXXGASXPVFGXGXWXSKPGX-VXXAVKXAIDIGXRHIDCAYVYGNXXXVGXAIT 290 +P V G P+ G G + + + +V A+ G R D A VYGN +G + Sbjct: 3 VPSVRLMSGTQMPLLGLGTYKLQDHEQLKQSVSCALQAGYRAFDTAAVYGNEAHLGQVLK 62 Query: 291 SKIKEGVVTRXXLFITSKLWNTFHRPDLVRGALQ 392 + + + R +FI SKL + H G L+ Sbjct: 63 ELLPKYGLIREDVFIISKLAPSDHGLRAKEGCLR 96 >UniRef50_Q28P63 Cluster: Aldo/keto reductase; n=4; Rhodobacteraceae|Rep: Aldo/keto reductase - Jannaschia sp. (strain CCS1) Length = 276 Score = 77.4 bits (182), Expect = 5e-13 Identities = 42/114 (36%), Positives = 64/114 (56%) Frame = +1 Query: 409 LNVQYLDLYLIHWPQAYKEDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGV 588 + V+ LDL LIHWP + D+ Y++TWKA + + EGL++SIG Sbjct: 98 IGVEQLDLVLIHWP-----------------VPSQDL-YLETWKAFQDMRDEGLMRSIGT 139 Query: 589 SNFNSKQLERLLQHATVKPVVNQVECHPYLNQKRLKEFCEARGVKITXYSPLGS 750 SNFN+ LER++ PV+NQ+E +P L Q ++ +A GV ++PLG+ Sbjct: 140 SNFNADHLERIIAETGEAPVLNQIELNPMLQQPEMRAVHKAHGVVTQAWTPLGN 193 Score = 55.6 bits (128), Expect = 2e-06 Identities = 30/95 (31%), Positives = 45/95 (47%) Frame = +3 Query: 117 PVVXFXXGASXPVFGXGXWXSKPGXVXXAVKXAIDIGXRHIDCAYVYGNXXXVGXAITSK 296 PV+ F GA P G G W V+ AI+IG R ID AY+Y N +G Sbjct: 5 PVIKFHDGAQIPQVGFGIWQVPQDIAGETVRSAIEIGYRMIDGAYLYMNEAGLGEG---- 60 Query: 297 IKEGVVTRXXLFITSKLWNTFHRPDLVRGALQEXL 401 ++ + R +F+T+K+WN R +++ L Sbjct: 61 LRASGLPRDEVFVTTKVWNNEQGAAKARASVERSL 95 >UniRef50_A2UAH0 Cluster: Aldo/keto reductase; n=1; Bacillus coagulans 36D1|Rep: Aldo/keto reductase - Bacillus coagulans 36D1 Length = 273 Score = 77.4 bits (182), Expect = 5e-13 Identities = 38/115 (33%), Positives = 65/115 (56%) Frame = +1 Query: 406 NLNVQYLDLYLIHWPQAYKEDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIG 585 N ++ LDLYLIH P + E G+ + + ++ WKAME + + G ++IG Sbjct: 99 NFGLEQLDLYLIHAPWPWSEKGADYTKEN-----------IEVWKAMEEIYESGRCRAIG 147 Query: 586 VSNFNSKQLERLLQHATVKPVVNQVECHPYLNQKRLKEFCEARGVKITXYSPLGS 750 VSNF+ L+ ++++A +KP+VNQ+ Q+ + FC+ G+ + YSPL + Sbjct: 148 VSNFSVSDLKAVMENAKIKPMVNQIRYFIGHTQEDVTAFCQDNGILVEAYSPLAT 202 Score = 47.2 bits (107), Expect = 6e-04 Identities = 27/71 (38%), Positives = 35/71 (49%), Gaps = 1/71 (1%) Frame = +3 Query: 138 GASXPVFGXGXWXSKPGXVXX-AVKXAIDIGXRHIDCAYVYGNXXXVGXAITSKIKEGVV 314 G + P G G W G AV A+ G RHID AY Y N VG A +++ + Sbjct: 13 GVAIPKIGLGTWQVPNGETTYHAVSFALKNGYRHIDTAYAYHNEESVGKA----VRDSGI 68 Query: 315 TRXXLFITSKL 347 R +F+TSKL Sbjct: 69 DRRDIFVTSKL 79 >UniRef50_Q7NB44 Cluster: ARA1; n=3; Firmicutes|Rep: ARA1 - Mycoplasma gallisepticum Length = 289 Score = 77.0 bits (181), Expect = 6e-13 Identities = 43/112 (38%), Positives = 64/112 (57%) Frame = +1 Query: 406 NLNVQYLDLYLIHWPQAYKEDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIG 585 +L+++YLDL LIHWP G F K + +V+ TWKAME EG +K+IG Sbjct: 105 DLDLEYLDLLLIHWPI-----GKGF------KDNWQEVN-AQTWKAMEEFYLEGKIKAIG 152 Query: 586 VSNFNSKQLERLLQHATVKPVVNQVECHPYLNQKRLKEFCEARGVKITXYSP 741 +SNF +E L + A + P+VNQ+E HP Q + E+C+ + + +SP Sbjct: 153 LSNFLVHHIEALKKSAKILPMVNQLEFHPGYLQPEIVEYCQKNNIVVQAWSP 204 Score = 52.0 bits (119), Expect = 2e-05 Identities = 27/69 (39%), Positives = 39/69 (56%), Gaps = 1/69 (1%) Frame = +3 Query: 150 PVFGXGXWXSKPGX-VXXAVKXAIDIGXRHIDCAYVYGNXXXVGXAITSKIKEGVVTRXX 326 P G G + + G AVK A+++G RH+DCA +Y N +++ IK V R Sbjct: 23 PSIGFGTYKLEDGKQTVEAVKTALEVGYRHLDCAEIYENQ----LSVSQGIKLSGVNRKE 78 Query: 327 LFITSKLWN 353 +FITSK+WN Sbjct: 79 IFITSKIWN 87 >UniRef50_Q043M4 Cluster: Aldo/keto reductase of diketogulonate reductase family; n=2; Lactobacillus|Rep: Aldo/keto reductase of diketogulonate reductase family - Lactobacillus gasseri (strain ATCC 33323 / DSM 20243) Length = 273 Score = 77.0 bits (181), Expect = 6e-13 Identities = 40/114 (35%), Positives = 61/114 (53%) Frame = +1 Query: 409 LNVQYLDLYLIHWPQAYKEDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGV 588 + + Y DL LIHWP + +DTW A+E K G ++IG+ Sbjct: 93 IGLDYFDLVLIHWPMGHD---------------------IDTWHALEAAYKAGKTRAIGI 131 Query: 589 SNFNSKQLERLLQHATVKPVVNQVECHPYLNQKRLKEFCEARGVKITXYSPLGS 750 SNFNS+Q L+ ++V+P+V+Q+E H +L Q ++ EF E + YSPLG+ Sbjct: 132 SNFNSRQTLDLIHQSSVRPMVDQIETHLFLQQWKMHEFLEKENIVHESYSPLGN 185 >UniRef50_Q07551 Cluster: NADPH-dependent alpha-keto amide reductase; n=4; Saccharomycetales|Rep: NADPH-dependent alpha-keto amide reductase - Saccharomyces cerevisiae (Baker's yeast) Length = 312 Score = 77.0 bits (181), Expect = 6e-13 Identities = 46/128 (35%), Positives = 64/128 (50%), Gaps = 2/128 (1%) Frame = +1 Query: 409 LNVQYLDLYLIHWPQAYKEDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGV 588 + Y+DLYL+H P KE L + WK ME L K G K+IGV Sbjct: 111 MGTDYVDLYLLHSPFVSKEVNGL--------------SLEEAWKDMEQLYKSGKAKNIGV 156 Query: 589 SNFNSKQLERLLQHATVKPVVNQVECHPYLNQKR--LKEFCEARGVKITXYSPLGSPDRP 762 SNF + L+R+L+ A VKP VNQ+E P+L + + +FC+ + + YSPLG + Sbjct: 157 SNFAVEDLQRILKVAEVKPQVNQIEFSPFLQNQTPGIYKFCQEHDILVEAYSPLGPLQKK 216 Query: 763 WGQARRPP 786 Q P Sbjct: 217 TAQDDSQP 224 >UniRef50_UPI00006CCCD7 Cluster: oxidoreductase, aldo/keto reductase family protein; n=1; Tetrahymena thermophila SB210|Rep: oxidoreductase, aldo/keto reductase family protein - Tetrahymena thermophila SB210 Length = 323 Score = 76.6 bits (180), Expect = 8e-13 Identities = 43/115 (37%), Positives = 63/115 (54%), Gaps = 2/115 (1%) Frame = +1 Query: 409 LNVQYLDLYLIHWPQAYKEDGSLFP--TDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSI 582 L Y+DLYLI W S P T+ G + + + W+ +E V+ G+++SI Sbjct: 115 LQTSYIDLYLIQW--------SFTPVLTNFDGSVAVNHRPIHEVWRELEECVELGMIRSI 166 Query: 583 GVSNFNSKQLERLLQHATVKPVVNQVECHPYLNQKRLKEFCEARGVKITXYSPLG 747 GV+NFN + + LL +A +KPVVNQ+E PYL Q L F + ++ SPLG Sbjct: 167 GVANFNCQMVLDLLSYAKIKPVVNQIEVTPYLPQIDLINFLKRCKIETVAISPLG 221 Score = 38.7 bits (86), Expect = 0.20 Identities = 22/71 (30%), Positives = 36/71 (50%) Frame = +3 Query: 213 AIDIGXRHIDCAYVYGNXXXVGXAITSKIKEGVVTRXXLFITSKLWNTFHRPDLVRGALQ 392 A+D G R+ D A Y N +G A + ++G R +FIT+KL+ F ++ +Q Sbjct: 51 ALDFGYRNFDTAKQYRNEVEIGQAFQNIFQQGKYKREDVFITTKLF-PFKIEKKIKEVVQ 109 Query: 393 EXLXQSERSVL 425 L Q + S + Sbjct: 110 NSLDQLQTSYI 120 >UniRef50_Q5XJM7 Cluster: Zgc:101765; n=5; Eumetazoa|Rep: Zgc:101765 - Danio rerio (Zebrafish) (Brachydanio rerio) Length = 288 Score = 76.6 bits (180), Expect = 8e-13 Identities = 42/121 (34%), Positives = 60/121 (49%) Frame = +1 Query: 388 CRXPWXNLNVQYLDLYLIHWPQAYKEDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEG 567 C+ L + Y+DLYLIHWP P + + +W+ +E EG Sbjct: 96 CQKSLEQLGLGYIDLYLIHWPGTQG-----LPVGDKRNPE----NRAQSWRVLEEFYSEG 146 Query: 568 LVKSIGVSNFNSKQLERLLQHATVKPVVNQVECHPYLNQKRLKEFCEARGVKITXYSPLG 747 ++IGVSN+ + ++ LL+ V P V QVE HP L Q L+ C+ RGV YS LG Sbjct: 147 KFRAIGVSNYTVEHMQELLKSCKVPPAVLQVEFHPKLLQNDLRGLCKIRGVCFQAYSSLG 206 Query: 748 S 750 + Sbjct: 207 T 207 Score = 35.9 bits (79), Expect = 1.4 Identities = 24/78 (30%), Positives = 35/78 (44%), Gaps = 1/78 (1%) Frame = +3 Query: 117 PVVXFXXGASXPVFGXGXWXSK-PGXVXXAVKXAIDIGXRHIDCAYVYGNXXXVGXAITS 293 P V P+ G G + + AV A+ G R D A VY N +G A+ Sbjct: 6 PSVLLNNDIQMPLLGLGTFRLQGQEDTYSAVDAALKAGYRAFDTAAVYRNEAHLGHALRC 65 Query: 294 KIKEGVVTRXXLFITSKL 347 + + ++R +FITSKL Sbjct: 66 LLPKHGLSREDVFITSKL 83 >UniRef50_Q6NII7 Cluster: Putative oxidoreductase; n=2; Corynebacterium|Rep: Putative oxidoreductase - Corynebacterium diphtheriae Length = 290 Score = 76.6 bits (180), Expect = 8e-13 Identities = 37/96 (38%), Positives = 49/96 (51%) Frame = +3 Query: 114 IPVVXFXXGASXPVFGXGXWXSKPGXVXXAVKXAIDIGXRHIDCAYVYGNXXXVGXAITS 293 IP + G P G G + + AV+ AI++G RHID A +Y N VG A+ Sbjct: 11 IPTITLNDGTEMPAIGFGTYKLREQDAYRAVRSAIEVGYRHIDTASLYKNEEEVGRAVAD 70 Query: 294 KIKEGVVTRXXLFITSKLWNTFHRPDLVRGALQEXL 401 I G V R LFIT+K+WN H L + + QE L Sbjct: 71 AITAGEVARDELFITTKVWNDMHGDQLTQRSFQESL 106 Score = 51.6 bits (118), Expect = 3e-05 Identities = 34/116 (29%), Positives = 56/116 (48%) Frame = +1 Query: 409 LNVQYLDLYLIHWPQAYKEDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGV 588 L + Y+D ++HWP +P Q G YV+++ A+ + G ++S+ V Sbjct: 109 LGLDYIDCCMVHWP---------WP--QKGL-------YVESFAALAKIQGLGQLQSVAV 150 Query: 589 SNFNSKQLERLLQHATVKPVVNQVECHPYLNQKRLKEFCEARGVKITXYSPLGSPD 756 +NF + L ++ + PV+NQVE HP +Q + GV +SPLG D Sbjct: 151 ANFYPEVLREIVAETGIAPVLNQVELHPGFSQAEQRAVDRELGVVTEAWSPLGRGD 206 >UniRef50_A1UEC5 Cluster: 2,5-didehydrogluconate reductase; n=20; Corynebacterineae|Rep: 2,5-didehydrogluconate reductase - Mycobacterium sp. (strain KMS) Length = 283 Score = 76.6 bits (180), Expect = 8e-13 Identities = 40/113 (35%), Positives = 58/113 (51%) Frame = +1 Query: 409 LNVQYLDLYLIHWPQAYKEDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGV 588 L + Y+DLYLIHWP GK Y+D+W + ++G+ +SIGV Sbjct: 105 LGLDYVDLYLIHWPAG-----------DHGK-------YIDSWGGLMKAKQDGVARSIGV 146 Query: 589 SNFNSKQLERLLQHATVKPVVNQVECHPYLNQKRLKEFCEARGVKITXYSPLG 747 NFN++ L ++ + P +NQ+E HP LNQ L+E G+ Y PLG Sbjct: 147 CNFNAEHLSNIIDLSFFTPAINQIELHPLLNQAELREVNAGYGIVTEAYGPLG 199 >UniRef50_Q09632 Cluster: Probable oxidoreductase ZK1290.5; n=2; Caenorhabditis|Rep: Probable oxidoreductase ZK1290.5 - Caenorhabditis elegans Length = 321 Score = 76.6 bits (180), Expect = 8e-13 Identities = 42/112 (37%), Positives = 62/112 (55%) Frame = +1 Query: 409 LNVQYLDLYLIHWPQAYKEDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGV 588 L YLD+Y+IH PQ D + + K TW+ ME L ++ V+SIGV Sbjct: 95 LQTDYLDMYMIHMPQL--PDWIVNQKETKEK----------TWRQMELLYEDEHVRSIGV 142 Query: 589 SNFNSKQLERLLQHATVKPVVNQVECHPYLNQKRLKEFCEARGVKITXYSPL 744 SN++ + L+ LL+ A++ P NQVE HP+ +Q LK +C+ G+ Y PL Sbjct: 143 SNYSIEDLDELLEFASILPHANQVELHPWFHQADLKNYCDELGILTMGYCPL 194 >UniRef50_P47137 Cluster: Probable oxidoreductase YJR096W; n=8; Saccharomycetales|Rep: Probable oxidoreductase YJR096W - Saccharomyces cerevisiae (Baker's yeast) Length = 282 Score = 76.2 bits (179), Expect = 1e-12 Identities = 32/75 (42%), Positives = 54/75 (72%), Gaps = 2/75 (2%) Frame = +1 Query: 526 VDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQHATV--KPVVNQVECHPYLNQKRLKE 699 ++TW+AM+ V EGLVKSIGVSN+ K ++ LL + KPVVNQ+E P++ ++ L + Sbjct: 125 LETWRAMQEAVDEGLVKSIGVSNYGKKHIDELLNWPELKHKPVVNQIEISPWIMRQELAD 184 Query: 700 FCEARGVKITXYSPL 744 +C+++G+ + ++PL Sbjct: 185 YCKSKGLVVEAFAPL 199 Score = 44.0 bits (99), Expect = 0.005 Identities = 26/92 (28%), Positives = 39/92 (42%), Gaps = 2/92 (2%) Frame = +3 Query: 138 GASXPVFGXGXWXSKPGXVXXAVKXAIDIGXRHIDCAYVYGNXXXVGXAITSKIKE--GV 311 G P G + V + G RH D A +YGN VG I + E G Sbjct: 11 GFKIPSIALGTYDIPRSQTAEIVYEGVKCGYRHFDTAVLYGNEKEVGDGIIKWLNEDPGN 70 Query: 312 VTRXXLFITSKLWNTFHRPDLVRGALQEXLXQ 407 R +F T+KLWN+ + + A+++ L + Sbjct: 71 HKREEIFYTTKLWNSQNGYKRAKAAIRQCLNE 102 >UniRef50_Q5NLW3 Cluster: Putative oxidoreductase; n=1; Zymomonas mobilis|Rep: Putative oxidoreductase - Zymomonas mobilis Length = 273 Score = 75.8 bits (178), Expect = 1e-12 Identities = 47/129 (36%), Positives = 62/129 (48%) Frame = +1 Query: 361 IARTWCAVPCRXPWXNLNVQYLDLYLIHWPQAYKEDGSLFPTDQSGKIQFSDVDYVDTWK 540 + R C V NL V L+LYLIHWP Q K Y +TW+ Sbjct: 79 MGRVNCFVALDKSIRNLGVTSLNLYLIHWP------------GQDRK------RYEETWQ 120 Query: 541 AMEPLVKEGLVKSIGVSNFNSKQLERLLQHATVKPVVNQVECHPYLNQKRLKEFCEARGV 720 + + G SIGVSNF L+ ++ + V P VNQ+E HPY QK L+ + RG+ Sbjct: 121 TLIQIRAIGKASSIGVSNFTIDHLDHIIADSGVVPAVNQIELHPYFQQKELRAYHAERGI 180 Query: 721 KITXYSPLG 747 T +SPLG Sbjct: 181 VTTSWSPLG 189 >UniRef50_Q5T2L2 Cluster: Aldo-keto reductase family 1 member C-like protein 1; n=14; Eutheria|Rep: Aldo-keto reductase family 1 member C-like protein 1 - Homo sapiens (Human) Length = 302 Score = 75.8 bits (178), Expect = 1e-12 Identities = 42/96 (43%), Positives = 50/96 (52%), Gaps = 3/96 (3%) Frame = +3 Query: 123 VXFXXGASXPVFGXGXWX---SKPGXVXXAVKXAIDIGXRHIDCAYVYGNXXXVGXAITS 293 V G PV G G + + A K AID+G RHID AY+Y N VG AI Sbjct: 11 VRLNDGPFMPVLGFGTYAPDHTPKSQAAEATKVAIDVGFRHIDSAYLYQNEEEVGQAIWE 70 Query: 294 KIKEGVVTRXXLFITSKLWNTFHRPDLVRGALQEXL 401 KI +G V R +F T KLW TF R +LV AL+ L Sbjct: 71 KIADGTVKREEIFYTIKLWATFFRAELVHPALERSL 106 Score = 72.1 bits (169), Expect = 2e-11 Identities = 47/120 (39%), Positives = 60/120 (50%), Gaps = 2/120 (1%) Frame = +1 Query: 409 LNVQYLDLYLIHWPQAYKEDGS-LFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIG 585 L Y+DL++IH P A K+ G L P D SG+I V+ DTW+ L K GL Sbjct: 109 LGPDYVDLFIIHVPFAMKQPGKELLPKDASGEIILETVELCDTWELELILNKPGL----- 163 Query: 586 VSNFNSKQLERLLQHATVKPVVNQV-ECHPYLNQKRLKEFCEARGVKITXYSPLGSPDRP 762 KP NQV ECHPYLNQ +L EFC+++ + + YS LGS P Sbjct: 164 ----------------RYKPTCNQVVECHPYLNQSKLLEFCKSKDIVLVAYSALGSQRDP 207 Score = 38.3 bits (85), Expect = 0.26 Identities = 17/47 (36%), Positives = 27/47 (57%) Frame = +2 Query: 746 ARRTDPGAKPDDPQXMEDPKLKXIADRLGKTVAQVLIRYQIDXGXIV 886 ++R PD P +E+P LK IA + ++ QV +RYQ+ G +V Sbjct: 203 SQRDPQWVDPDCPHLLEEPILKSIAKKHSRSPGQVALRYQLQRGVVV 249 >UniRef50_A5BF24 Cluster: Putative uncharacterized protein; n=1; Vitis vinifera|Rep: Putative uncharacterized protein - Vitis vinifera (Grape) Length = 212 Score = 75.4 bits (177), Expect = 2e-12 Identities = 38/84 (45%), Positives = 49/84 (58%) Frame = +1 Query: 406 NLNVQYLDLYLIHWPQAYKEDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIG 585 NL + YLDLYLIHW + K P ++ + +D WKAME K L K+IG Sbjct: 82 NLQLDYLDLYLIHWSVSLKPGNYELPVNKDDHLP---IDLGSVWKAMEDFQKLSLTKAIG 138 Query: 586 VSNFNSKQLERLLQHATVKPVVNQ 657 VSNF+ +LE LLQ A++ P VNQ Sbjct: 139 VSNFSCNKLEELLQTASILPAVNQ 162 Score = 38.7 bits (86), Expect = 0.20 Identities = 19/52 (36%), Positives = 30/52 (57%), Gaps = 1/52 (1%) Frame = +3 Query: 201 AVKXAIDIGXRHIDCAYVYGNXXXVGXAITSKIKEGVV-TRXXLFITSKLWN 353 ++ AI++G RH DC Y + +G AI +K G++ +R LFIT + N Sbjct: 31 SILTAIELGYRHFDCVAAYLSEKPLGEAIKKAVKLGLIKSRDELFITLQALN 82 >UniRef50_Q927E1 Cluster: Lin2848 protein; n=13; Listeria|Rep: Lin2848 protein - Listeria innocua Length = 280 Score = 74.5 bits (175), Expect = 3e-12 Identities = 43/113 (38%), Positives = 62/113 (54%) Frame = +1 Query: 409 LNVQYLDLYLIHWPQAYKEDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGV 588 L + +DLYL+HWP K+D + +TW+A+E L EGLV++IGV Sbjct: 101 LQLDQVDLYLVHWP---KQD-----------------TFFETWRAVEKLYDEGLVRAIGV 140 Query: 589 SNFNSKQLERLLQHATVKPVVNQVECHPYLNQKRLKEFCEARGVKITXYSPLG 747 SNF + L+RL A V PVV+Q+E HP+ + L + E + +SPLG Sbjct: 141 SNFEAHHLDRLRTSANVLPVVDQLETHPHFPNQLLHRYLEELHIVHQAWSPLG 193 Score = 35.9 bits (79), Expect = 1.4 Identities = 22/74 (29%), Positives = 34/74 (45%), Gaps = 1/74 (1%) Frame = +3 Query: 138 GASXPVFGXGXWX-SKPGXVXXAVKXAIDIGXRHIDCAYVYGNXXXVGXAITSKIKEGVV 314 G P G G + + + A++ A+D+G R D A Y N +G S + Sbjct: 14 GIEMPRHGFGVYKLTDEQRMRTALETAVDVGYRLFDTASFYHNEKELGDFFASS----GL 69 Query: 315 TRXXLFITSKLWNT 356 R F+T+K+WNT Sbjct: 70 KRDEFFVTTKMWNT 83 >UniRef50_Q8G7K9 Cluster: Dehydrogenase or reductase protein; n=4; Bifidobacterium|Rep: Dehydrogenase or reductase protein - Bifidobacterium longum Length = 289 Score = 74.5 bits (175), Expect = 3e-12 Identities = 38/112 (33%), Positives = 56/112 (50%) Frame = +1 Query: 409 LNVQYLDLYLIHWPQAYKEDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGV 588 L + Y+D+Y+IHWP + D DTWKA L EG+ +++GV Sbjct: 109 LQLDYVDMYMIHWPTPF------------------DWRSTDTWKAFVKLRDEGMARTLGV 150 Query: 589 SNFNSKQLERLLQHATVKPVVNQVECHPYLNQKRLKEFCEARGVKITXYSPL 744 NF L+RL + P VNQ+E HP Q+ + FC+ G+ + YSP+ Sbjct: 151 CNFMPADLKRLHEETGAWPAVNQIELHPTWQQREVVAFCKEHGIAVEAYSPM 202 Score = 42.3 bits (95), Expect = 0.016 Identities = 25/78 (32%), Positives = 35/78 (44%) Frame = +3 Query: 114 IPVVXFXXGASXPVFGXGXWXSKPGXVXXAVKXAIDIGXRHIDCAYVYGNXXXVGXAITS 293 +P + G S P G G V V+ A++ G RHID A Y N VG A+ + Sbjct: 11 VPDIALKDGHSIPQVGLGVLRIDDEGVVPVVESALEAGYRHIDGAAGYNNEAGVGRALAA 70 Query: 294 KIKEGVVTRXXLFITSKL 347 R L++T+KL Sbjct: 71 SGYNKGAKRETLWVTTKL 88 >UniRef50_Q8ZI40 Cluster: 2,5-diketo-D-gluconic acid reductase A; n=74; Bacteria|Rep: 2,5-diketo-D-gluconic acid reductase A - Yersinia pestis Length = 277 Score = 74.5 bits (175), Expect = 3e-12 Identities = 40/112 (35%), Positives = 59/112 (52%) Frame = +1 Query: 409 LNVQYLDLYLIHWPQAYKEDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGV 588 L + Y+DLYLIHWP K+D YV W+ + L ++GL++SIGV Sbjct: 96 LQLDYVDLYLIHWPDP-KQD-----------------HYVSAWRELVTLKEQGLIRSIGV 137 Query: 589 SNFNSKQLERLLQHATVKPVVNQVECHPYLNQKRLKEFCEARGVKITXYSPL 744 NF+ L+RL+ + P VNQ+E HP L Q++L + + +SPL Sbjct: 138 CNFHIPHLQRLIDETGIAPTVNQIELHPLLQQRQLHAWNATHHIATESWSPL 189 Score = 57.2 bits (132), Expect = 5e-07 Identities = 30/79 (37%), Positives = 39/79 (49%) Frame = +3 Query: 117 PVVXFXXGASXPVFGXGXWXSKPGXVXXAVKXAIDIGXRHIDCAYVYGNXXXVGXAITSK 296 P++ G P G G W + AV A+++G R ID A +Y N VG A+ Sbjct: 5 PLIKLYDGRLMPQLGLGVWQASIQETELAVSKALEVGYRSIDTAAIYKNEEGVGKAL--- 61 Query: 297 IKEGVVTRXXLFITSKLWN 353 K V R LFIT+KLWN Sbjct: 62 -KAAAVARDELFITTKLWN 79 >UniRef50_A7P424 Cluster: Chromosome chr1 scaffold_5, whole genome shotgun sequence; n=1; Vitis vinifera|Rep: Chromosome chr1 scaffold_5, whole genome shotgun sequence - Vitis vinifera (Grape) Length = 247 Score = 73.7 bits (173), Expect = 6e-12 Identities = 51/126 (40%), Positives = 63/126 (50%), Gaps = 2/126 (1%) Frame = +1 Query: 406 NLNVQYLDLYLIHWPQAYKEDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIG 585 NL + YLDLYLIHW DG L +D WKAME K L K+IG Sbjct: 115 NLQLDYLDLYLIHW-----SDGHL------------PIDLGSVWKAMEDFQKLSLTKAIG 157 Query: 586 VSNFNSKQLERLLQHATVKPVVNQV-ECHPYLNQKRLKEFCEAR-GVKITXYSPLGSPDR 759 VSNF+ +LE LLQ A++ P VNQV E P L + + R V I+ ++P P Sbjct: 158 VSNFSCNKLEELLQTASILPAVNQVSENEPTLAAEEAQGVIYVRKRVSISRHTPPWVPKE 217 Query: 760 PWGQAR 777 WG R Sbjct: 218 HWGTDR 223 Score = 52.0 bits (119), Expect = 2e-05 Identities = 28/68 (41%), Positives = 39/68 (57%), Gaps = 1/68 (1%) Frame = +3 Query: 201 AVKXAIDIGXRHIDCAYVYGNXXXVGXAITSKIKEGVV-TRXXLFITSKLWNTFHRPDLV 377 ++ AI++G RH DC Y + +G AI +K G++ +R LFITSKLW + D V Sbjct: 37 SILTAIELGYRHFDCVAAYLSEKPLGEAIKKAVKLGLIKSRDELFITSKLWCSDAHHDRV 96 Query: 378 RGALQEXL 401 ALQ L Sbjct: 97 LPALQNTL 104 >UniRef50_Q21274 Cluster: Putative uncharacterized protein; n=1; Caenorhabditis elegans|Rep: Putative uncharacterized protein - Caenorhabditis elegans Length = 301 Score = 73.7 bits (173), Expect = 6e-12 Identities = 40/112 (35%), Positives = 63/112 (56%) Frame = +1 Query: 409 LNVQYLDLYLIHWPQAYKEDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGV 588 L Y+DL LIH+P+ ++ G+ D +I S V W+ +E + G V+SIGV Sbjct: 109 LQTDYVDLLLIHYPRD-RDTGN----DDDYEINKSRRKIV--WQTLEKAKESGRVRSIGV 161 Query: 589 SNFNSKQLERLLQHATVKPVVNQVECHPYLNQKRLKEFCEARGVKITXYSPL 744 SN+ L + ++A ++PV+NQ E PYL + LK+FC+ + + YS L Sbjct: 162 SNYEVYHLVEMFEYAKIRPVLNQYEYQPYLTRPTLKKFCDLNNIVVQSYSSL 213 >UniRef50_Q4JX70 Cluster: Putative oxidoreductase; n=1; Corynebacterium jeikeium K411|Rep: Putative oxidoreductase - Corynebacterium jeikeium (strain K411) Length = 285 Score = 73.3 bits (172), Expect = 8e-12 Identities = 34/87 (39%), Positives = 46/87 (52%) Frame = +3 Query: 93 INKMAPXIPVVXFXXGASXPVFGXGXWXSKPGXVXXAVKXAIDIGXRHIDCAYVYGNXXX 272 +N+ +P + G + P G G W +V+ AI+ G RHID A +YGN Sbjct: 1 MNEKNNAVPTLEMNDGKTTPQLGLGVWQLSDEDTYTSVRAAIETGYRHIDTAAIYGNEEA 60 Query: 273 VGXAITSKIKEGVVTRXXLFITSKLWN 353 VG A+ +K G V R LFIT+KLWN Sbjct: 61 VGRAVADAVKAGDVQREELFITTKLWN 87 Score = 53.6 bits (123), Expect = 7e-06 Identities = 38/113 (33%), Positives = 53/113 (46%) Frame = +1 Query: 409 LNVQYLDLYLIHWPQAYKEDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGV 588 L + Y+DLYL+HWP P S +V + +M + + G SIGV Sbjct: 104 LGMDYVDLYLLHWP---------CPQADS---------FVQAYDSMAEIQQSGGATSIGV 145 Query: 589 SNFNSKQLERLLQHATVKPVVNQVECHPYLNQKRLKEFCEARGVKITXYSPLG 747 NF + L+ L Q A P VNQ+E HP +Q + RG+ +SPLG Sbjct: 146 CNFYPEALDALKQ-AGHTPAVNQIEIHPGFSQAEQRSDNRDRGIVTEAWSPLG 197 Score = 33.1 bits (72), Expect = 9.9 Identities = 15/36 (41%), Positives = 21/36 (58%) Frame = +2 Query: 785 QXMEDPKLKXIADRLGKTVAQVLIRYQIDXGXIVXP 892 Q + DP + IA G +VAQ +IR+ I G +V P Sbjct: 200 QNLTDPTIAKIAAEHGVSVAQAIIRWHIQRGDVVIP 235 >UniRef50_Q4FY75 Cluster: Aldo-keto reductase-like protein; n=5; Trypanosomatidae|Rep: Aldo-keto reductase-like protein - Leishmania major strain Friedlin Length = 372 Score = 73.3 bits (172), Expect = 8e-12 Identities = 49/134 (36%), Positives = 66/134 (49%), Gaps = 12/134 (8%) Frame = +1 Query: 388 CRXPWXNLNVQYLDLYLIHWPQAYKE------DGSLFPTDQSGKIQF-SDVDYVDTWKAM 546 CR L + YLDLYLIHWP + D +P + G + V +DTW AM Sbjct: 110 CRATLAALQLDYLDLYLIHWPVCMRHTPHWTSDEDRYPRHRDGTPAIDTSVTLLDTWTAM 169 Query: 547 EPLVKEGLVKSIGVSNFNSKQLERLLQH-ATVK----PVVNQVECHPYLNQKRLKEFCEA 711 LV GLVKSIG++N + + L++ A K PV+NQVE HP + L + Sbjct: 170 NRLVDRGLVKSIGLANCTTAHVNDLVKAVAEAKLAHLPVLNQVEHHPGIVDGDLIGCLGS 229 Query: 712 RGVKITXYSPLGSP 753 + + Y PLG P Sbjct: 230 HDMLMAAYCPLGMP 243 Score = 64.9 bits (151), Expect = 3e-09 Identities = 32/84 (38%), Positives = 40/84 (47%) Frame = +3 Query: 150 PVFGXGXWXSKPGXVXXAVKXAIDIGXRHIDCAYVYGNXXXVGXAITSKIKEGVVTRXXL 329 P G G + AV A+ G RH+DCA YGN VG A+ ++ R L Sbjct: 31 PQLGFGTYRLPVSEATDAVAFALSCGYRHVDCAKAYGNEAAVGEALAQALRTRCTRREDL 90 Query: 330 FITSKLWNTFHRPDLVRGALQEXL 401 F+TSKLW T PD V A + L Sbjct: 91 FVTSKLWPTDQHPDHVEAACRATL 114 >UniRef50_A1CAM7 Cluster: Aldo-keto reductase, putative; n=9; Dikarya|Rep: Aldo-keto reductase, putative - Aspergillus clavatus Length = 283 Score = 72.9 bits (171), Expect = 1e-11 Identities = 32/73 (43%), Positives = 48/73 (65%), Gaps = 1/73 (1%) Frame = +1 Query: 529 DTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQHATV-KPVVNQVECHPYLNQKRLKEFC 705 + W+A+E L++EG KSIGVSNF K +E + +A V P VNQ+E HP+ Q+ + +C Sbjct: 127 ELWQALEKLLEEGKTKSIGVSNFGVKHIEEMKAYAKVWPPHVNQIELHPWCQQRVIDAYC 186 Query: 706 EARGVKITXYSPL 744 + G+ + YSPL Sbjct: 187 KRNGIVVEAYSPL 199 Score = 33.5 bits (73), Expect = 7.5 Identities = 15/33 (45%), Positives = 20/33 (60%) Frame = +2 Query: 797 DPKLKXIADRLGKTVAQVLIRYQIDXGXIVXPE 895 DP L +A + GKT AQVLIRY + + P+ Sbjct: 207 DPTLVDLAKKYGKTTAQVLIRYALQKHWVPLPK 239 >UniRef50_P15339 Cluster: 2,5-diketo-D-gluconic acid reductase B; n=6; Actinomycetales|Rep: 2,5-diketo-D-gluconic acid reductase B - Corynebacterium sp. (strain SHS752001) Length = 277 Score = 72.9 bits (171), Expect = 1e-11 Identities = 42/112 (37%), Positives = 57/112 (50%) Frame = +1 Query: 409 LNVQYLDLYLIHWPQAYKEDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGV 588 L + +DL LIHW P G+ ++DTW+ M + GLV+SIGV Sbjct: 98 LGLDVIDLQLIHW-----------PNPSVGR-------WLDTWRGMIDAREAGLVRSIGV 139 Query: 589 SNFNSKQLERLLQHATVKPVVNQVECHPYLNQKRLKEFCEARGVKITXYSPL 744 SNF L+ L+ V P VNQVE HPY Q L+ F + G++ +SPL Sbjct: 140 SNFTEPMLKTLIDETGVTPAVNQVELHPYFPQAALRAFHDEHGIRTESWSPL 191 >UniRef50_A5PDA8 Cluster: Putative oxidoreductase protein; n=1; Erythrobacter sp. SD-21|Rep: Putative oxidoreductase protein - Erythrobacter sp. SD-21 Length = 272 Score = 72.5 bits (170), Expect = 1e-11 Identities = 40/113 (35%), Positives = 59/113 (52%) Frame = +1 Query: 409 LNVQYLDLYLIHWPQAYKEDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGV 588 L +++D+ LIHWP K+ +VDTWKA+ L G KSIGV Sbjct: 94 LGREHVDMLLIHWPCPEKDQ------------------FVDTWKALIELRDAGKAKSIGV 135 Query: 589 SNFNSKQLERLLQHATVKPVVNQVECHPYLNQKRLKEFCEARGVKITXYSPLG 747 SNF + L+R++ V P +NQ+E HP Q+ +++ E G+ +SPLG Sbjct: 136 SNFREEDLKRIIDETGVTPALNQIELHPSFQQRDMRKVHEDLGIVTQSWSPLG 188 Score = 46.0 bits (104), Expect = 0.001 Identities = 30/100 (30%), Positives = 42/100 (42%) Frame = +3 Query: 117 PVVXFXXGASXPVFGXGXWXSKPGXVXXAVKXAIDIGXRHIDCAYVYGNXXXVGXAITSK 296 P + G P G G W + AV AID+G ID A +YGN VG Sbjct: 5 PTLNLNDGRQIPQLGFGTWQMEEEDAPQAVSTAIDVGYWLIDTAAIYGNEKGVG------ 58 Query: 297 IKEGVVTRXXLFITSKLWNTFHRPDLVRGALQEXLXQSER 416 +GV +F+ +K+WN D A ++ L + R Sbjct: 59 --KGVGEWSDIFLQTKIWNDSQGYDRTLRAAEKCLERLGR 96 >UniRef50_Q4WUF7 Cluster: Aldo-keto reductase, putative; n=3; Pezizomycotina|Rep: Aldo-keto reductase, putative - Aspergillus fumigatus (Sartorya fumigata) Length = 283 Score = 72.1 bits (169), Expect = 2e-11 Identities = 31/73 (42%), Positives = 49/73 (67%), Gaps = 1/73 (1%) Frame = +1 Query: 529 DTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQHATV-KPVVNQVECHPYLNQKRLKEFC 705 + W+A+E L++EG +SIGVSNF K +E + +A V P VNQ+E HP+ Q+ ++ +C Sbjct: 127 ELWQALERLLEEGKTRSIGVSNFGVKHIEEMKAYAKVWPPHVNQIELHPWCQQRVIEAYC 186 Query: 706 EARGVKITXYSPL 744 + G+ + YSPL Sbjct: 187 KRNGIVVEAYSPL 199 Score = 41.5 bits (93), Expect = 0.028 Identities = 25/82 (30%), Positives = 39/82 (47%) Frame = +3 Query: 150 PVFGXGXWXSKPGXVXXAVKXAIDIGXRHIDCAYVYGNXXXVGXAITSKIKEGVVTRXXL 329 P G G + S G + A++ G RHID A YGN VG A +++ + R + Sbjct: 21 PRLGFGVYRSPTGQCVQSSLRALEAGYRHIDTAQFYGNEKEVGEA----LRKCGIPRSDV 76 Query: 330 FITSKLWNTFHRPDLVRGALQE 395 F+T+K+ + P+ L E Sbjct: 77 FVTTKILSPAGSPEATYQKLLE 98 >UniRef50_Q02198 Cluster: Morphine 6-dehydrogenase; n=5; Bacteria|Rep: Morphine 6-dehydrogenase - Pseudomonas putida Length = 296 Score = 72.1 bits (169), Expect = 2e-11 Identities = 42/113 (37%), Positives = 59/113 (52%) Frame = +1 Query: 409 LNVQYLDLYLIHWPQAYKEDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGV 588 L + Y+DLYL+HWP D + IQ +WKA E ++ +G ++IGV Sbjct: 99 LGLDYVDLYLLHWPTK----------DWNATIQ--------SWKAAEKILGDGRARAIGV 140 Query: 589 SNFNSKQLERLLQHATVKPVVNQVECHPYLNQKRLKEFCEARGVKITXYSPLG 747 NF QL+ L+ + V P VNQ+E HPY QK L A G+ +SP+G Sbjct: 141 CNFLEDQLDELIAASDVVPAVNQIELHPYFAQKPLLAKNRALGIVTEAWSPIG 193 >UniRef50_Q5FK98 Cluster: Oxidoreductase; n=8; Lactobacillales|Rep: Oxidoreductase - Lactobacillus acidophilus Length = 285 Score = 71.3 bits (167), Expect = 3e-11 Identities = 39/115 (33%), Positives = 65/115 (56%) Frame = +1 Query: 406 NLNVQYLDLYLIHWPQAYKEDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIG 585 +L + YLD+YLIHWP S + +++++ ++W+AME V+ G +++IG Sbjct: 101 DLKLDYLDMYLIHWPNP-----------SSMRDHWAEIN-AESWRAMEEAVRAGKIRAIG 148 Query: 586 VSNFNSKQLERLLQHATVKPVVNQVECHPYLNQKRLKEFCEARGVKITXYSPLGS 750 VSNF L+ L++ A +KPVVNQ+ +P Q + + + YSPLG+ Sbjct: 149 VSNFRKHHLDALMETAEIKPVVNQIFLNPSDLQSEVVTENKKLDLLSEAYSPLGT 203 Score = 63.7 bits (148), Expect = 6e-09 Identities = 36/89 (40%), Positives = 48/89 (53%), Gaps = 1/89 (1%) Frame = +3 Query: 138 GASXPVFGXGXWXSKPGXVXX-AVKXAIDIGXRHIDCAYVYGNXXXVGXAITSKIKEGVV 314 G P+ G G W + G V +V A++ G RHID A YGN VG AI K G + Sbjct: 15 GVKIPIIGFGTWQTPDGEVAEESVLAALNCGYRHIDTASAYGNEDSVGRAIQ---KSG-I 70 Query: 315 TRXXLFITSKLWNTFHRPDLVRGALQEXL 401 R LFIT+KLWN+ H + + A+ + L Sbjct: 71 NRHELFITTKLWNSDHGYEKTKKAIDQSL 99 >UniRef50_Q4WP69 Cluster: Aldehyde reductase, putative; n=1; Aspergillus fumigatus|Rep: Aldehyde reductase, putative - Aspergillus fumigatus (Sartorya fumigata) Length = 350 Score = 70.9 bits (166), Expect = 4e-11 Identities = 41/103 (39%), Positives = 57/103 (55%), Gaps = 7/103 (6%) Frame = +1 Query: 406 NLNVQYLDLYLI----HWPQAYKEDGSLFPTDQSGKIQFS--DVDYVDTWKAMEPLVKEG 567 +L YLDLYL+ H Y+ P + G +F D+ DTW A E LV G Sbjct: 129 DLQTNYLDLYLLYPLGHILHTYQRH---IPASRPGHKRFRLVDIPIGDTWAAREKLVNAG 185 Query: 568 LVKSIGVSN-FNSKQLERLLQHATVKPVVNQVECHPYLNQKRL 693 ++S+GVSN F +++E LL A + P VNQ+E HPYL Q ++ Sbjct: 186 KIRSLGVSNLFTIEKMEELLNTADIPPAVNQIEAHPYLLQPKI 228 Score = 44.4 bits (100), Expect = 0.004 Identities = 27/68 (39%), Positives = 35/68 (51%) Frame = +3 Query: 222 IGXRHIDCAYVYGNXXXVGXAITSKIKEGVVTRXXLFITSKLWNTFHRPDLVRGALQEXL 401 +G RHID A V N VG K+ V R +F+TSKLWNT H P V AL + + Sbjct: 72 VGYRHIDSAAVGLNEAEVGRGW----KKLGVPREGIFLTSKLWNTHHHPSHVEEALDKTV 127 Query: 402 XQSERSVL 425 + + L Sbjct: 128 KDLQTNYL 135 >UniRef50_Q8ET73 Cluster: 2,5-diketo-D-gluconate reductase; n=12; Bacteria|Rep: 2,5-diketo-D-gluconate reductase - Oceanobacillus iheyensis Length = 280 Score = 70.5 bits (165), Expect = 5e-11 Identities = 38/111 (34%), Positives = 58/111 (52%) Frame = +1 Query: 412 NVQYLDLYLIHWPQAYKEDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVS 591 N+ Y DLYLIHWP + D+ YV+ W+A+ + G ++SIGV Sbjct: 100 NLDYYDLYLIHWPNPIQ-----------------DI-YVEAWQALIEAKRRGYIRSIGVC 141 Query: 592 NFNSKQLERLLQHATVKPVVNQVECHPYLNQKRLKEFCEARGVKITXYSPL 744 NF + LERL Q P +NQ+E HP+ NQ+ +++ + + +SPL Sbjct: 142 NFLPEHLERLKQETGELPTINQIELHPFFNQEDQRKWHQEHQIATESWSPL 192 Score = 50.4 bits (115), Expect = 6e-05 Identities = 35/103 (33%), Positives = 44/103 (42%) Frame = +3 Query: 102 MAPXIPVVXFXXGASXPVFGXGXWXSKPGXVXXAVKXAIDIGXRHIDCAYVYGNXXXVGX 281 M IP V G + P G G + A+ AID G R ID AY Y N VG Sbjct: 1 MVNQIPNVTLHDGLTIPKVGFGTYRLNGNDGVQAINNAIDHGYRLIDTAYNYENEGTVGE 60 Query: 282 AITSKIKEGVVTRXXLFITSKLWNTFHRPDLVRGALQEXLXQS 410 A+ + R L ITSKL +H D +QE L ++ Sbjct: 61 AV----RRSSTPREQLLITSKLPGRYHHYDKAVTTIQESLYRA 99 >UniRef50_A5DRJ6 Cluster: Putative uncharacterized protein; n=4; Pichia guilliermondii|Rep: Putative uncharacterized protein - Pichia guilliermondii (Yeast) (Candida guilliermondii) Length = 287 Score = 70.5 bits (165), Expect = 5e-11 Identities = 31/75 (41%), Positives = 48/75 (64%), Gaps = 2/75 (2%) Frame = +1 Query: 526 VDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLL--QHATVKPVVNQVECHPYLNQKRLKE 699 ++TWKA++ V G+VKSIGVSNF ++ L + KP+VNQ+E P+L +K L + Sbjct: 128 IETWKALQEAVDSGMVKSIGVSNFGKHHIQELYDWEGLKYKPIVNQIELSPWLMRKDLVD 187 Query: 700 FCEARGVKITXYSPL 744 +C+ G+ + Y PL Sbjct: 188 YCQNLGIVLEAYCPL 202 Score = 37.5 bits (83), Expect = 0.46 Identities = 16/35 (45%), Positives = 23/35 (65%) Frame = +2 Query: 791 MEDPKLKXIADRLGKTVAQVLIRYQIDXGXIVXPE 895 + DP L +A + KT AQVL+R+ ID G +V P+ Sbjct: 208 LNDPTLVKLAKKYNKTPAQVLLRWNIDRGVVVIPK 242 >UniRef50_Q6CEJ0 Cluster: Yarrowia lipolytica chromosome B of strain CLIB122 of Yarrowia lipolytica; n=1; Yarrowia lipolytica|Rep: Yarrowia lipolytica chromosome B of strain CLIB122 of Yarrowia lipolytica - Yarrowia lipolytica (Candida lipolytica) Length = 302 Score = 70.1 bits (164), Expect = 7e-11 Identities = 41/116 (35%), Positives = 60/116 (51%), Gaps = 2/116 (1%) Frame = +1 Query: 409 LNVQYLDLYLIHWPQAYKEDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGV 588 L Y DL+LIH P P D + D W +E L ++GL K+IGV Sbjct: 104 LQTDYFDLFLIHVP----------PNDDI------NYDLAKAWGVLEQLYEKGLAKAIGV 147 Query: 589 SNFNSKQLERLLQHATVKPVVNQVECHPYLNQKR--LKEFCEARGVKITXYSPLGS 750 SN + +LE +++ A +KP VNQ+E HP L + + +FC+ + + YSPL S Sbjct: 148 SNHSPAELETIIKVAKIKPHVNQIEFHPLLQEPTPGIVDFCKQHDIVVEGYSPLAS 203 Score = 42.3 bits (95), Expect = 0.016 Identities = 31/85 (36%), Positives = 37/85 (43%), Gaps = 8/85 (9%) Frame = +3 Query: 114 IPVVXFXXGASXPVFGXGX---WXSKPGX-----VXXAVKXAIDIGXRHIDCAYVYGNXX 269 +P V G P G G W PG + AV AI+ G HID A YG Sbjct: 3 VPKVKLSNGLEIPAIGFGSGTKWKRPPGEKEERELIDAVVSAINAGHLHIDTAEFYGTEK 62 Query: 270 XVGXAITSKIKEGVVTRXXLFITSK 344 +G A IKE V R +F+TSK Sbjct: 63 QIGEA----IKESGVPRKDIFLTSK 83 >UniRef50_P82125 Cluster: 1,5-anhydro-D-fructose reductase; n=1; Sus scrofa|Rep: 1,5-anhydro-D-fructose reductase - Sus scrofa (Pig) Length = 206 Score = 70.1 bits (164), Expect = 7e-11 Identities = 37/66 (56%), Positives = 40/66 (60%), Gaps = 1/66 (1%) Frame = +3 Query: 150 PVFGXGXWXSKPGX-VXXAVKXAIDIGXRHIDCAYVYGNXXXVGXAITSKIKEGVVTRXX 326 PV G G W + PG V AVK AID G RH D AY+Y N VG I +KI EGVV R Sbjct: 3 PVLGLGTWQAAPGGEVTEAVKVAIDTGYRHPDSAYLYHNEDEVGVGIQAKIDEGVVRRED 62 Query: 327 LFITSK 344 LFI SK Sbjct: 63 LFIVSK 68 Score = 42.7 bits (96), Expect(2) = 1e-07 Identities = 19/35 (54%), Positives = 23/35 (65%) Frame = +1 Query: 643 PVVNQVECHPYLNQKRLKEFCEARGVKITXYSPLG 747 PV NQ+E HPYL QK F ++R V +T Y PLG Sbjct: 109 PVTNQIESHPYLTQK--ISFXQSRNVSVTAYRPLG 141 Score = 36.7 bits (81), Expect(2) = 1e-07 Identities = 16/35 (45%), Positives = 20/35 (57%) Frame = +1 Query: 421 YLDLYLIHWPQAYKEDGSLFPTDQSGKIQFSDVDY 525 YLDL IHWP +K P D+SG I S+ D+ Sbjct: 72 YLDLXNIHWPMQFKPGEVDLPVDRSGMIVASNTDF 106 >UniRef50_Q9P734 Cluster: Related to 2, 5-diketo-D-gluconic acid reductase; n=5; Pezizomycotina|Rep: Related to 2, 5-diketo-D-gluconic acid reductase - Neurospora crassa Length = 289 Score = 69.7 bits (163), Expect = 9e-11 Identities = 31/72 (43%), Positives = 45/72 (62%), Gaps = 1/72 (1%) Frame = +1 Query: 532 TWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQHA-TVKPVVNQVECHPYLNQKRLKEFCE 708 +WKA+E V G VK GVSN+ K L+ ++ +KP+VNQ+ECHP+ Q ++ CE Sbjct: 135 SWKAVEDAVLAGEVKMAGVSNYGVKHLDEVMSAPFKIKPLVNQIECHPFNTQPEIRAACE 194 Query: 709 ARGVKITXYSPL 744 G+ I Y+PL Sbjct: 195 KYGIVIEAYAPL 206 >UniRef50_Q9C1X5 Cluster: Xylose and arabinose reductase; n=1; Schizosaccharomyces pombe|Rep: Xylose and arabinose reductase - Schizosaccharomyces pombe (Fission yeast) Length = 283 Score = 69.3 bits (162), Expect = 1e-10 Identities = 30/74 (40%), Positives = 47/74 (63%), Gaps = 1/74 (1%) Frame = +1 Query: 526 VDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLL-QHATVKPVVNQVECHPYLNQKRLKEF 702 + +WKAME V G ++S+GVSN+ K L+ L + P VNQ+E HP+L+Q + ++ Sbjct: 125 IASWKAMEEFVDSGDIRSVGVSNYGVKHLQELYASNPKFYPCVNQIELHPFLSQDDIVKY 184 Query: 703 CEARGVKITXYSPL 744 C++ + I YSPL Sbjct: 185 CQSHDIAIEAYSPL 198 Score = 51.2 bits (117), Expect = 3e-05 Identities = 30/77 (38%), Positives = 36/77 (46%) Frame = +3 Query: 123 VXFXXGASXPVFGXGXWXSKPGXVXXAVKXAIDIGXRHIDCAYVYGNXXXVGXAITSKIK 302 V G P G G + K V A+D G RHID A VYGN G AI + Sbjct: 11 VTLTNGMVIPRIGFGAFMLKYNECYGLVTQALDSGYRHIDTAAVYGNEDICGKAIVDWCE 70 Query: 303 EGVVTRXXLFITSKLWN 353 + V R +F+TSKL N Sbjct: 71 KNNVKRTDIFLTSKLAN 87 >UniRef50_Q83N50 Cluster: 2,5-diketo-D-gluconic acid reductase; n=2; Tropheryma whipplei|Rep: 2,5-diketo-D-gluconic acid reductase - Tropheryma whipplei (strain Twist) (Whipple's bacillus) Length = 283 Score = 68.9 bits (161), Expect = 2e-10 Identities = 37/111 (33%), Positives = 60/111 (54%) Frame = +1 Query: 409 LNVQYLDLYLIHWPQAYKEDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGV 588 L++ Y+DLYLIHWP P++ Y++ W+ + L + G KS+GV Sbjct: 101 LSLDYVDLYLIHWPCP--------PSEL----------YINVWEVLLELKESGRAKSVGV 142 Query: 589 SNFNSKQLERLLQHATVKPVVNQVECHPYLNQKRLKEFCEARGVKITXYSP 741 SNF S+ ++++ + P VNQ+E HP+L Q+ L C G++I + P Sbjct: 143 SNFLSEHIDKIKEAGFPLPSVNQIELHPWLQQRELVLSCRNDGIQIESWGP 193 Score = 62.5 bits (145), Expect = 1e-08 Identities = 32/81 (39%), Positives = 42/81 (51%) Frame = +3 Query: 114 IPVVXFXXGASXPVFGXGXWXSKPGXVXXAVKXAIDIGXRHIDCAYVYGNXXXVGXAITS 293 +P V G S P FG G + P V+ AI++G RHID A +Y N VG AI S Sbjct: 9 VPSVLLGDGVSIPQFGLGTYELPPNEASSVVQSAIELGYRHIDTASLYANEREVGRAIAS 68 Query: 294 KIKEGVVTRXXLFITSKLWNT 356 + R F+T+KLWN+ Sbjct: 69 ----SGIKREEFFVTTKLWNS 85 >UniRef50_P06632 Cluster: 2,5-diketo-D-gluconic acid reductase A; n=8; Actinomycetales|Rep: 2,5-diketo-D-gluconic acid reductase A - Corynebacterium sp. (strain ATCC 31090) Length = 278 Score = 68.9 bits (161), Expect = 2e-10 Identities = 37/96 (38%), Positives = 49/96 (51%) Frame = +3 Query: 114 IPVVXFXXGASXPVFGXGXWXSKPGXVXXAVKXAIDIGXRHIDCAYVYGNXXXVGXAITS 293 +P + G S P G G + P AV+ A+++G RHID A +YGN VG AI + Sbjct: 3 VPSIVLNDGNSIPQLGYGVFKVPPADTQRAVEEALEVGYRHIDTAAIYGNEEGVGAAIAA 62 Query: 294 KIKEGVVTRXXLFITSKLWNTFHRPDLVRGALQEXL 401 + R LFIT+KLWN H D A+ E L Sbjct: 63 ----SGIARDDLFITTKLWNDRHDGDEPAAAIAESL 94 Score = 67.7 bits (158), Expect = 4e-10 Identities = 40/113 (35%), Positives = 55/113 (48%) Frame = +1 Query: 409 LNVQYLDLYLIHWPQAYKEDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGV 588 L + +DLYL+HWP ++ YV W+ M L GL +SIGV Sbjct: 97 LALDQVDLYLVHWPTPAADN------------------YVHAWEKMIELRAAGLTRSIGV 138 Query: 589 SNFNSKQLERLLQHATVKPVVNQVECHPYLNQKRLKEFCEARGVKITXYSPLG 747 SN LER++ V P VNQ+E HP Q+ + ++ A VKI + PLG Sbjct: 139 SNHLVPHLERIVAATGVVPAVNQIELHPAYQQREITDWAAAHDVKIESWGPLG 191 >UniRef50_A7BES9 Cluster: Putative uncharacterized protein; n=1; Actinomyces odontolyticus ATCC 17982|Rep: Putative uncharacterized protein - Actinomyces odontolyticus ATCC 17982 Length = 282 Score = 68.5 bits (160), Expect = 2e-10 Identities = 30/76 (39%), Positives = 45/76 (59%) Frame = +1 Query: 520 DYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQHATVKPVVNQVECHPYLNQKRLKE 699 D V ++ +E KEG +++IG+SNF+ Q +R+L V P +NQVECHPY Q LK Sbjct: 108 DTVAGYRILEKAHKEGKIRAIGLSNFDVAQTQRILDECEVVPTINQVECHPYFPQTELKA 167 Query: 700 FCEARGVKITXYSPLG 747 + + + + PLG Sbjct: 168 LLKDHNITLQAWYPLG 183 >UniRef50_Q75E75 Cluster: ABL209Cp; n=1; Eremothecium gossypii|Rep: ABL209Cp - Ashbya gossypii (Yeast) (Eremothecium gossypii) Length = 310 Score = 68.5 bits (160), Expect = 2e-10 Identities = 31/73 (42%), Positives = 48/73 (65%), Gaps = 2/73 (2%) Frame = +1 Query: 532 TWKAMEPLVKEGLVKSIGVSNFNSKQLERLL--QHATVKPVVNQVECHPYLNQKRLKEFC 705 TW+A+E V EG V+SIGVSN+ + L LL + ++PVVNQVE +P+L ++ L ++C Sbjct: 133 TWQALEEAVVEGQVRSIGVSNYGQQHLSELLGWEGLKIRPVVNQVEINPWLCRQELVQYC 192 Query: 706 EARGVKITXYSPL 744 + + +SPL Sbjct: 193 RENNIAVQAFSPL 205 Score = 35.9 bits (79), Expect = 1.4 Identities = 15/35 (42%), Positives = 24/35 (68%) Frame = +2 Query: 791 MEDPKLKXIADRLGKTVAQVLIRYQIDXGXIVXPE 895 ++DP L+ +A + K VAQ+L+R+ I G IV P+ Sbjct: 211 LDDPILQKVAHQYDKGVAQILVRWSIQMGFIVLPK 245 >UniRef50_Q5KCN9 Cluster: Putative uncharacterized protein; n=1; Filobasidiella neoformans|Rep: Putative uncharacterized protein - Cryptococcus neoformans (Filobasidiella neoformans) Length = 295 Score = 68.5 bits (160), Expect = 2e-10 Identities = 42/116 (36%), Positives = 57/116 (49%), Gaps = 4/116 (3%) Frame = +1 Query: 409 LNVQYLDLYLIHWPQAYKEDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGV 588 + V Y+DLYL+H P + S+ + W ME + EGL KSIGV Sbjct: 101 MGVDYVDLYLLHSPLLFAPKYSIN----------------EAWAIMEEIKSEGLAKSIGV 144 Query: 589 SNFNSKQLERLLQHATVKPVVNQVECHPYL----NQKRLKEFCEARGVKITXYSPL 744 SNF + L L + + P VNQ+E HPY N RL++FC + + I Y PL Sbjct: 145 SNFREEDLMELQKTWKIVPSVNQIEFHPYNYHADNMVRLQDFCHSNKITIQCYGPL 200 >UniRef50_Q4PE96 Cluster: Putative uncharacterized protein; n=1; Ustilago maydis|Rep: Putative uncharacterized protein - Ustilago maydis (Smut fungus) Length = 293 Score = 68.5 bits (160), Expect = 2e-10 Identities = 30/74 (40%), Positives = 45/74 (60%), Gaps = 1/74 (1%) Frame = +1 Query: 526 VDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQHAT-VKPVVNQVECHPYLNQKRLKEF 702 +D+W + LV+EG V+S+GVSNF ++ L+ V PV NQ+ECHP+ QK ++ Sbjct: 133 LDSWDTLTELVQEGKVRSLGVSNFGPHHIQELIDSKPKVLPVCNQIECHPFFAQKEVRAA 192 Query: 703 CEARGVKITXYSPL 744 EA + + Y PL Sbjct: 193 SEAHSIIVQAYCPL 206 Score = 35.1 bits (77), Expect = 2.5 Identities = 14/33 (42%), Positives = 21/33 (63%) Frame = +2 Query: 797 DPKLKXIADRLGKTVAQVLIRYQIDXGXIVXPE 895 DP LK +A GKT AQV++R+ + G + P+ Sbjct: 214 DPTLKKVAAETGKTEAQVMLRWLVQHGIVALPK 246 >UniRef50_Q5V398 Cluster: Oxidoreductase aldo/keto reductase family; n=1; Haloarcula marismortui|Rep: Oxidoreductase aldo/keto reductase family - Haloarcula marismortui (Halobacterium marismortui) Length = 302 Score = 68.5 bits (160), Expect = 2e-10 Identities = 31/75 (41%), Positives = 46/75 (61%) Frame = +1 Query: 520 DYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQHATVKPVVNQVECHPYLNQKRLKE 699 D +T+ A+ LV +GLV IGVSNF+ K+L++ ++ + NQ+E HPY + L Sbjct: 123 DMEETFNALNTLVDDGLVGQIGVSNFSIKELKQAMRLSDAPIATNQIEYHPYWGDEELVR 182 Query: 700 FCEARGVKITXYSPL 744 FC+ V +T YSPL Sbjct: 183 FCQDNDVTVTAYSPL 197 Score = 41.5 bits (93), Expect = 0.028 Identities = 24/66 (36%), Positives = 33/66 (50%) Frame = +3 Query: 150 PVFGXGXWXSKPGXVXXAVKXAIDIGXRHIDCAYVYGNXXXVGXAITSKIKEGVVTRXXL 329 P G G + + AVK A+D G HID A Y N VG A I++ V R + Sbjct: 21 PTLGFGTYRTGGYKCYNAVKNALDCGYTHIDTAMAYENEAAVGRA----IEQSSVDREDI 76 Query: 330 FITSKL 347 F+T+K+ Sbjct: 77 FLTTKI 82 >UniRef50_Q5UX52 Cluster: Oxidoreductase aldo/keto reductase family; n=1; Haloarcula marismortui|Rep: Oxidoreductase aldo/keto reductase family - Haloarcula marismortui (Halobacterium marismortui) Length = 274 Score = 68.5 bits (160), Expect = 2e-10 Identities = 41/112 (36%), Positives = 58/112 (51%) Frame = +1 Query: 409 LNVQYLDLYLIHWPQAYKEDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGV 588 L YLDL LIHWP T + +T AM +V+EGLV+ IGV Sbjct: 94 LGTDYLDLLLIHWPN----------TPWMASLS-------ETLGAMNDVVEEGLVRHIGV 136 Query: 589 SNFNSKQLERLLQHATVKPVVNQVECHPYLNQKRLKEFCEARGVKITXYSPL 744 SNF+ L+R ++ +QV+ HPY +Q++L ++C V +T YSPL Sbjct: 137 SNFSPSLLDRARDISSAPIFTDQVQYHPYWDQRKLLDYCRIHDVLLTAYSPL 188 Score = 47.2 bits (107), Expect = 6e-04 Identities = 29/88 (32%), Positives = 40/88 (45%) Frame = +3 Query: 138 GASXPVFGXGXWXSKPGXVXXAVKXAIDIGXRHIDCAYVYGNXXXVGXAITSKIKEGVVT 317 G S P G G W V+ A+ +G RHID A YGN VG + + V Sbjct: 8 GTSVPALGLGTWQLTGQSCRETVETALGMGYRHIDTAQAYGNERQVGLGMDA----AAVD 63 Query: 318 RXXLFITSKLWNTFHRPDLVRGALQEXL 401 R +F+T+KL + VR + +E L Sbjct: 64 REDVFLTTKLDGSNRDERSVRRSTRESL 91 >UniRef50_UPI00006CA3CB Cluster: oxidoreductase, aldo/keto reductase family protein; n=3; Tetrahymena thermophila SB210|Rep: oxidoreductase, aldo/keto reductase family protein - Tetrahymena thermophila SB210 Length = 299 Score = 68.1 bits (159), Expect = 3e-10 Identities = 40/112 (35%), Positives = 57/112 (50%) Frame = +1 Query: 409 LNVQYLDLYLIHWPQAYKEDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGV 588 L V Y+DL LIH P A P+D + V + W E + GL K +GV Sbjct: 104 LQVDYVDLLLIHVPLAA-------PSDDYQQWNHKPVHQI--WAEFEEIHSLGLAKGLGV 154 Query: 589 SNFNSKQLERLLQHATVKPVVNQVECHPYLNQKRLKEFCEARGVKITXYSPL 744 SNFN + + LL + +KP+VNQ+E H + QK L EF + + +SP+ Sbjct: 155 SNFNCQMIIDLLAYCKIKPLVNQIELHVFNQQKNLVEFLKKVNIYPVAFSPM 206 Score = 46.4 bits (105), Expect = 0.001 Identities = 24/76 (31%), Positives = 37/76 (48%), Gaps = 1/76 (1%) Frame = +3 Query: 120 VVXFXXGASXPVFGXGXWXSKP-GXVXXAVKXAIDIGXRHIDCAYVYGNXXXVGXAITSK 296 V+ G P FG G + V ++ A+D+G RHID A +Y N +G A+ + Sbjct: 9 VITLSNGQKMPAFGLGSSRVQSVEEVTNLIRKALDVGYRHIDTAQMYENEQFIGAALKTI 68 Query: 297 IKEGVVTRXXLFITSK 344 EG R +F+ +K Sbjct: 69 FGEGKYKREDIFLVTK 84 >UniRef50_Q5KD52 Cluster: Oxidoreductase, putative; n=1; Filobasidiella neoformans|Rep: Oxidoreductase, putative - Cryptococcus neoformans (Filobasidiella neoformans) Length = 321 Score = 68.1 bits (159), Expect = 3e-10 Identities = 55/146 (37%), Positives = 68/146 (46%), Gaps = 21/146 (14%) Frame = +1 Query: 409 LNVQYLDLYLIHWPQAYKEDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGV 588 L ++YLDLYLIH PQ K D WK +E L KEG KSIGV Sbjct: 98 LGLEYLDLYLIHSPQVTKGD------------------IKGAWKELETLQKEGKTKSIGV 139 Query: 589 S------------------NFNSKQLERLLQHATVKPVVNQVECHPYLNQKR--LKEFCE 708 S +FN +QL+ LL HATVKPVVNQ+ HPY+ + L E+ E Sbjct: 140 SKQVYYQTIFFASLSDVWDSFNKEQLQELLAHATVKPVVNQILLHPYVITRTAPLLEYLE 199 Query: 709 ARGVKITXYSPL-GSPDRPWGQARRP 783 + + YS L RP G +P Sbjct: 200 EQNIVAEGYSTLIPLTSRPGGPVDKP 225 Score = 37.5 bits (83), Expect = 0.46 Identities = 27/75 (36%), Positives = 34/75 (45%), Gaps = 3/75 (4%) Frame = +3 Query: 138 GASXPVFGXGXWXSKPGXVXXAVKXAIDIGXRHIDCA---YVYGNXXXVGXAITSKIKEG 308 G P G W V AID+G HID A VY N VG A IKE Sbjct: 11 GHRIPAIAFGTWKIPKEVTPFQVGQAIDVGFDHIDTAQGRIVYHNEEEVGQA----IKES 66 Query: 309 VVTRXXLFITSKLWN 353 ++R L++T+K W+ Sbjct: 67 GLSRNQLWVTTK-WS 80 >UniRef50_Q1Q8W8 Cluster: Aldo/keto reductase; n=1; Psychrobacter cryohalolentis K5|Rep: Aldo/keto reductase - Psychrobacter cryohalolentis (strain K5) Length = 282 Score = 67.7 bits (158), Expect = 4e-10 Identities = 42/117 (35%), Positives = 58/117 (49%) Frame = +1 Query: 406 NLNVQYLDLYLIHWPQAYKEDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIG 585 NL+ Y+DL L+HWP V +T A+ L K+GL ++IG Sbjct: 100 NLDTDYVDLLLLHWPD-------------------DRVPLSETIPALCELQKQGLTRNIG 140 Query: 586 VSNFNSKQLERLLQHATVKPVVNQVECHPYLNQKRLKEFCEARGVKITXYSPLGSPD 756 VSNFN + ++A V VVNQVE HP++ QK L+ F + + YSPL D Sbjct: 141 VSNFNIANIIEAKRYADVPIVVNQVEFHPFIKQKTLQTFLNNHHILLEAYSPLARGD 197 Score = 46.0 bits (104), Expect = 0.001 Identities = 25/70 (35%), Positives = 33/70 (47%) Frame = +3 Query: 141 ASXPVFGXGXWXSKPGXVXXAVKXAIDIGXRHIDCAYVYGNXXXVGXAITSKIKEGVVTR 320 A+ PV G G W S V + +G HID A YGN VG IK+ V R Sbjct: 14 ANIPVLGLGTWQSTGQDCIDVVSQGLRMGYEHIDTAQAYGNEVEVGKG----IKQSGVAR 69 Query: 321 XXLFITSKLW 350 F+T+K++ Sbjct: 70 DKFFLTTKIF 79 >UniRef50_Q11BF8 Cluster: Aldo/keto reductase; n=12; Bacteria|Rep: Aldo/keto reductase - Mesorhizobium sp. (strain BNC1) Length = 308 Score = 67.7 bits (158), Expect = 4e-10 Identities = 29/71 (40%), Positives = 45/71 (63%) Frame = +1 Query: 535 WKAMEPLVKEGLVKSIGVSNFNSKQLERLLQHATVKPVVNQVECHPYLNQKRLKEFCEAR 714 ++A+E L+ +G V++IGVSNF + L RLL ++ P VNQ+E HPY Q+ L+ Sbjct: 137 YRALEKLLADGKVRAIGVSNFMPEHLTRLLTETSIVPAVNQIEVHPYFQQRALQRLHAEH 196 Query: 715 GVKITXYSPLG 747 G+ +SP+G Sbjct: 197 GILTQAWSPIG 207 Score = 50.4 bits (115), Expect = 6e-05 Identities = 25/71 (35%), Positives = 36/71 (50%) Frame = +3 Query: 138 GASXPVFGXGXWXSKPGXVXXAVKXAIDIGXRHIDCAYVYGNXXXVGXAITSKIKEGVVT 317 G P+ G G + + P AV+ A+ +G RHID A YGN VG I+ + Sbjct: 26 GVEMPMIGLGVFQTPPDETTAAVEEALRLGYRHIDTAAAYGNEREVGEG----IRRAGIA 81 Query: 318 RXXLFITSKLW 350 R +FI +K+W Sbjct: 82 RDEVFIETKIW 92 Score = 34.7 bits (76), Expect = 3.3 Identities = 15/35 (42%), Positives = 23/35 (65%) Frame = +2 Query: 791 MEDPKLKXIADRLGKTVAQVLIRYQIDXGXIVXPE 895 +EDP L IA + GK+ AQV++R+ + G V P+ Sbjct: 220 LEDPVLLEIAQQHGKSAAQVMLRWHLQEGRSVIPK 254 >UniRef50_Q4DJ59 Cluster: Aldo/keto reductase, putative; n=2; Trypanosoma|Rep: Aldo/keto reductase, putative - Trypanosoma cruzi Length = 322 Score = 67.7 bits (158), Expect = 4e-10 Identities = 41/123 (33%), Positives = 58/123 (47%), Gaps = 11/123 (8%) Frame = +1 Query: 409 LNVQYLDLYLIHWPQAYKEDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGV 588 L + Y D LIHWP G L P + G WK M+ L KEG+++ +GV Sbjct: 110 LRIAYADCVLIHWPGC----GGLKPEEAEGHRAARH----RCWKVMQALKKEGIIRHLGV 161 Query: 589 SNFNSKQLERLLQHAT-----------VKPVVNQVECHPYLNQKRLKEFCEARGVKITXY 735 SNF + L+ +A +PV+NQ+E HP Q+ +FC R + + Y Sbjct: 162 SNFAPRHFPHLVGNAAEEAHLFDAANPCRPVINQIELHPLCVQQEACDFCRERDIILQQY 221 Query: 736 SPL 744 SPL Sbjct: 222 SPL 224 >UniRef50_Q8EUH6 Cluster: Oxidoreductase; n=1; Mycoplasma penetrans|Rep: Oxidoreductase - Mycoplasma penetrans Length = 285 Score = 67.3 bits (157), Expect = 5e-10 Identities = 31/76 (40%), Positives = 44/76 (57%) Frame = +1 Query: 520 DYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQHATVKPVVNQVECHPYLNQKRLKE 699 DY WKA+E L K+G+VK+IGVSNF + +L H VKPV+NQ+E HP + Sbjct: 112 DYYSAWKALEVLYKKGIVKAIGVSNFEADRLVDFCLHVDVKPVINQIELHPLRQRIEDLH 171 Query: 700 FCEARGVKITXYSPLG 747 + GV + ++ G Sbjct: 172 WNNKYGVAVESWASFG 187 Score = 41.5 bits (93), Expect = 0.028 Identities = 26/72 (36%), Positives = 36/72 (50%), Gaps = 1/72 (1%) Frame = +3 Query: 138 GASXPVFGXGXWXSKPGXVXXAVKXAID-IGXRHIDCAYVYGNXXXVGXAITSKIKEGVV 314 G P+ G G + ++ + AID G R ID A VY N VG AI K+ + Sbjct: 9 GLHMPIIGLGVYKAEGENCENTIIKAIDDYGYRMIDTAQVYFNEEFVGNAI----KQTKI 64 Query: 315 TRXXLFITSKLW 350 R +FIT+K+W Sbjct: 65 KREDIFITTKVW 76 Score = 33.1 bits (72), Expect = 9.9 Identities = 13/37 (35%), Positives = 24/37 (64%) Frame = +2 Query: 785 QXMEDPKLKXIADRLGKTVAQVLIRYQIDXGXIVXPE 895 + ME+P L +A++ KTV Q+++R+ I +V P+ Sbjct: 192 EIMENPILVSLAEKYNKTVPQIILRWLIQQNIVVIPK 228 >UniRef50_A3UJS6 Cluster: Oxidoreductase; n=3; Alphaproteobacteria|Rep: Oxidoreductase - Oceanicaulis alexandrii HTCC2633 Length = 275 Score = 67.3 bits (157), Expect = 5e-10 Identities = 40/112 (35%), Positives = 54/112 (48%) Frame = +1 Query: 409 LNVQYLDLYLIHWPQAYKEDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGV 588 L Y+DL L+HWP +V +T KAM + + G V+ IGV Sbjct: 95 LKTDYVDLLLLHWP-------------------VPEVPIAETMKAMNEVKEAGQVRHIGV 135 Query: 589 SNFNSKQLERLLQHATVKPVVNQVECHPYLNQKRLKEFCEARGVKITXYSPL 744 SNF L+ H+ V NQVE HPYL+Q + C A G+ +T YSP+ Sbjct: 136 SNFTVDLLDEARAHSGAPLVANQVEYHPYLDQNAVLTACRAAGMAMTAYSPI 187 Score = 52.0 bits (119), Expect = 2e-05 Identities = 29/88 (32%), Positives = 41/88 (46%) Frame = +3 Query: 138 GASXPVFGXGXWXSKPGXVXXAVKXAIDIGXRHIDCAYVYGNXXXVGXAITSKIKEGVVT 317 GA P G G W + V A+ G RHID A +YGN VG K+ V Sbjct: 9 GADIPKLGFGTWQLEDEDAARGVATALKTGYRHIDTAQIYGNEAAVGDG----WKQSGVK 64 Query: 318 RXXLFITSKLWNTFHRPDLVRGALQEXL 401 R F+T+K+W R ++ +++E L Sbjct: 65 REDFFLTTKVWRDKFRDGDLQASVKESL 92 >UniRef50_Q64UK5 Cluster: Aldo/keto reductase family oxidoreductase; n=1; Bacteroides fragilis|Rep: Aldo/keto reductase family oxidoreductase - Bacteroides fragilis Length = 151 Score = 66.9 bits (156), Expect = 7e-10 Identities = 36/102 (35%), Positives = 55/102 (53%) Frame = +1 Query: 421 YLDLYLIHWPQAYKEDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFN 600 Y+DL LIHWP A K + W+ ME V G +++IGVSNFN Sbjct: 69 YVDLMLIHWPVARKVK--------------------ERWRIMEKYVDVGKIRAIGVSNFN 108 Query: 601 SKQLERLLQHATVKPVVNQVECHPYLNQKRLKEFCEARGVKI 726 ++ LL +A +KPVVNQ++ HPY+ + + A+G+++ Sbjct: 109 PHHVDELLAYARIKPVVNQIKIHPYMEHQEVVGNTFAKGIQV 150 >UniRef50_A0JRJ3 Cluster: 2,5-didehydrogluconate reductase; n=3; Actinobacteria (class)|Rep: 2,5-didehydrogluconate reductase - Arthrobacter sp. (strain FB24) Length = 276 Score = 66.9 bits (156), Expect = 7e-10 Identities = 39/114 (34%), Positives = 56/114 (49%) Frame = +1 Query: 409 LNVQYLDLYLIHWPQAYKEDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGV 588 L + Y+DL LIHWP +++ ++ TWK E L +G V+SIGV Sbjct: 98 LGLDYVDLLLIHWPLPRRDE------------------FISTWKTFERLQADGKVRSIGV 139 Query: 589 SNFNSKQLERLLQHATVKPVVNQVECHPYLNQKRLKEFCEARGVKITXYSPLGS 750 SNF LERL+ V P VNQ++ P + + + G+ YSPLG+ Sbjct: 140 SNFKPAHLERLMAACDVVPAVNQIQVSPAITRIVDIAYNRRHGIVTESYSPLGA 193 Score = 52.0 bits (119), Expect = 2e-05 Identities = 33/85 (38%), Positives = 38/85 (44%) Frame = +3 Query: 117 PVVXFXXGASXPVFGXGXWXSKPGXVXXAVKXAIDIGXRHIDCAYVYGNXXXVGXAITSK 296 PV+ G P G G W V AV A++ G RHID A YGN VG I S Sbjct: 5 PVIELNDGHRIPQIGLGTWPLDDHQVAAAVVNAVEGGYRHIDTAVKYGNEKGVGNGIRS- 63 Query: 297 IKEGVVTRXXLFITSKLWNTFHRPD 371 + R LFIT+KL F D Sbjct: 64 ---SGLDRSELFITTKLDGEFQGQD 85 >UniRef50_A6VNW9 Cluster: Aldo/keto reductase precursor; n=1; Actinobacillus succinogenes 130Z|Rep: Aldo/keto reductase precursor - Actinobacillus succinogenes 130Z Length = 315 Score = 66.5 bits (155), Expect = 9e-10 Identities = 30/82 (36%), Positives = 46/82 (56%) Frame = +1 Query: 502 IQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQHATVKPVVNQVECHPYLN 681 + + D + WK ME VK G +++IG+SN++ K R++Q AT+ P V Q E H Y Sbjct: 145 LHYPDQNDTKAWKVMEQFVKAGKIRAIGLSNYHRKTFNRIMQAATITPAVVQNEVHIYNQ 204 Query: 682 QKRLKEFCEARGVKITXYSPLG 747 K+ K F G ++ + PLG Sbjct: 205 DKQTKAFLRNYGTQMEAWYPLG 226 >UniRef50_Q6L139 Cluster: 2,5-diketo-D-gluconic acid reductase; n=1; Picrophilus torridus|Rep: 2,5-diketo-D-gluconic acid reductase - Picrophilus torridus Length = 283 Score = 66.5 bits (155), Expect = 9e-10 Identities = 42/122 (34%), Positives = 60/122 (49%), Gaps = 3/122 (2%) Frame = +1 Query: 388 CRXPWXNLNVQYLDLYLIHWPQAYKEDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEG 567 C LNV+ +DLY +HWP + VD +T KAME LV G Sbjct: 84 CENSLKRLNVKTIDLYQLHWPNRH-------------------VDIKETMKAMEHLVDTG 124 Query: 568 LVKSIGVSNFNSKQLERLLQHATVKPVV-NQVECHPYLN--QKRLKEFCEARGVKITXYS 738 +++ IGVSNFN +L+ + + +V NQVE +P + + + EFC + I YS Sbjct: 125 MIRYIGVSNFNVNELKSAMSAMSKYEIVSNQVEYNPLVRYIEPEISEFCRKNSISIIAYS 184 Query: 739 PL 744 PL Sbjct: 185 PL 186 >UniRef50_Q9X0A2 Cluster: Oxidoreductase, aldo/keto reductase family; n=21; Bacteria|Rep: Oxidoreductase, aldo/keto reductase family - Thermotoga maritima Length = 286 Score = 66.1 bits (154), Expect = 1e-09 Identities = 40/111 (36%), Positives = 57/111 (51%) Frame = +1 Query: 409 LNVQYLDLYLIHWPQAYKEDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGV 588 L ++Y+DLYLIH P F DV WKAME + K+GLV++IGV Sbjct: 101 LQLEYIDLYLIHQP-------------------FGDVHCA--WKAMEEMYKDGLVRAIGV 139 Query: 589 SNFNSKQLERLLQHATVKPVVNQVECHPYLNQKRLKEFCEARGVKITXYSP 741 SNF +L L+ H + P VNQ+E HP+ ++ EF ++ + P Sbjct: 140 SNFYPDRLMDLMVHHEIVPAVNQIEIHPFYQRQEEIEFMRNYNIQPEAWGP 190 Score = 61.7 bits (143), Expect = 2e-08 Identities = 32/79 (40%), Positives = 39/79 (49%) Frame = +3 Query: 114 IPVVXFXXGASXPVFGXGXWXSKPGXVXXAVKXAIDIGXRHIDCAYVYGNXXXVGXAITS 293 +P V G P+ G G + P V AI +G R ID A Y N VG AI Sbjct: 3 VPKVTLNNGVEMPILGYGVFQIPPEKTEECVYEAIKVGYRLIDTAASYMNEEGVGRAIKR 62 Query: 294 KIKEGVVTRXXLFITSKLW 350 I EG+V R LF+T+KLW Sbjct: 63 AIDEGIVRREELFVTTKLW 81 >UniRef50_Q76L37 Cluster: Conjugated polyketone reductase C1; n=3; Saccharomycetales|Rep: Conjugated polyketone reductase C1 - Candida parapsilosis (Yeast) Length = 304 Score = 66.1 bits (154), Expect = 1e-09 Identities = 40/117 (34%), Positives = 62/117 (52%), Gaps = 3/117 (2%) Frame = +1 Query: 406 NLNVQYLDLYLIHWPQAYKEDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIG 585 +L ++Y+DLYLIH+P ++ D V+ W+ +E EGL ++IG Sbjct: 113 DLGLEYVDLYLIHFPYISEKSHGF--------------DLVEAWRYLERAKNEGLARNIG 158 Query: 586 VSNFNSKQLERLLQHATVK-PVVNQVECHPYLNQKR--LKEFCEARGVKITXYSPLG 747 VSNF + L+ +L T PVVNQ+E YL + + E+ + +G+ I Y PLG Sbjct: 159 VSNFTIENLKSILDANTDSIPVVNQIEFSAYLQDQTPGIVEYSQQQGILIEAYGPLG 215 >UniRef50_UPI000023DF27 Cluster: hypothetical protein FG07276.1; n=1; Gibberella zeae PH-1|Rep: hypothetical protein FG07276.1 - Gibberella zeae PH-1 Length = 284 Score = 65.7 bits (153), Expect = 2e-09 Identities = 30/76 (39%), Positives = 47/76 (61%), Gaps = 1/76 (1%) Frame = +1 Query: 535 WKAMEPLVKEGLVKSIGVSNFNSKQLERLLQHATV-KPVVNQVECHPYLNQKRLKEFCEA 711 W+AME +E ++IGVSNF + L+ + ++AT P VNQ+E HP+ QK + ++C+ Sbjct: 131 WEAMERAKREARARNIGVSNFRVRHLDEMKEYATEWPPSVNQIELHPWCQQKEVVKYCQD 190 Query: 712 RGVKITXYSPLGSPDR 759 + I YSPL + R Sbjct: 191 NEIIIEAYSPLATGAR 206 >UniRef50_Q03XK0 Cluster: Aldo/keto reductase of diketogulonate reductase family; n=3; Lactobacillales|Rep: Aldo/keto reductase of diketogulonate reductase family - Leuconostoc mesenteroides subsp. mesenteroides (strain ATCC 8293 /NCDO 523) Length = 292 Score = 65.3 bits (152), Expect = 2e-09 Identities = 38/111 (34%), Positives = 60/111 (54%) Frame = +1 Query: 409 LNVQYLDLYLIHWPQAYKEDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGV 588 LN+ YLDLYLIH P ++DV W+AME + G +K+IGV Sbjct: 100 LNLDYLDLYLIHQP-------------------YNDV--FGAWRAMESAYRSGQLKAIGV 138 Query: 589 SNFNSKQLERLLQHATVKPVVNQVECHPYLNQKRLKEFCEARGVKITXYSP 741 SNF+ QL L + + +KP++NQ+E +P+ K+ + GV++ ++P Sbjct: 139 SNFDIAQLTNLAEFSDIKPMLNQIEVNPFQQNKKDITYFSQYGVQVEAWAP 189 Score = 57.6 bits (133), Expect = 4e-07 Identities = 31/72 (43%), Positives = 38/72 (52%), Gaps = 1/72 (1%) Frame = +3 Query: 138 GASXPVFGXGXWX-SKPGXVXXAVKXAIDIGXRHIDCAYVYGNXXXVGXAITSKIKEGVV 314 G P+ G G + + G AV AI G R ID A YGN VG AI I +G+V Sbjct: 9 GIEMPLLGFGVFQVQEKGAAKQAVLDAIKTGYRLIDTAASYGNEREVGEAILEAINQGIV 68 Query: 315 TRXXLFITSKLW 350 R LF+TSK+W Sbjct: 69 KREELFVTSKMW 80 >UniRef50_Q5K8C5 Cluster: Aldo-keto reductase, putative; n=1; Filobasidiella neoformans|Rep: Aldo-keto reductase, putative - Cryptococcus neoformans (Filobasidiella neoformans) Length = 303 Score = 65.3 bits (152), Expect = 2e-09 Identities = 27/72 (37%), Positives = 40/72 (55%) Frame = +1 Query: 529 DTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQHATVKPVVNQVECHPYLNQKRLKEFCE 708 + WKA+ +GLVKSIGVSNF K ++ + P VNQV+ HP++ + E CE Sbjct: 149 NVWKALCDAQSQGLVKSIGVSNFGKKHIQEFIDQKVPLPTVNQVDLHPFMRHPEIVEICE 208 Query: 709 ARGVKITXYSPL 744 + + + PL Sbjct: 209 QNEILLEAWGPL 220 Score = 49.2 bits (112), Expect = 1e-04 Identities = 26/72 (36%), Positives = 35/72 (48%) Frame = +3 Query: 138 GASXPVFGXGXWXSKPGXVXXAVKXAIDIGXRHIDCAYVYGNXXXVGXAITSKIKEGVVT 317 G + P FG G + VK A++ G RH+D A Y N G AI +K + Sbjct: 38 GNAIPQFGLGVYEMNDKETYDCVKWALEAGYRHVDTAEWYENEAPCGKAIADFLKATGTS 97 Query: 318 RXXLFITSKLWN 353 R +F+TSKL N Sbjct: 98 REEIFLTSKLKN 109 >UniRef50_A6RYK4 Cluster: Putative uncharacterized protein; n=1; Botryotinia fuckeliana B05.10|Rep: Putative uncharacterized protein - Botryotinia fuckeliana B05.10 Length = 182 Score = 65.3 bits (152), Expect = 2e-09 Identities = 30/79 (37%), Positives = 42/79 (53%) Frame = +1 Query: 529 DTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQHATVKPVVNQVECHPYLNQKRLKEFCE 708 D W ME + G K+IGV NF LE ++ A+ P VNQ+E H YL Q L +C+ Sbjct: 20 DVWAEMEAVKASGKAKAIGVCNFAISHLETIIAGASEIPAVNQIEYHAYLQQSELSAYCQ 79 Query: 709 ARGVKITXYSPLGSPDRPW 765 G+K+ ++ L PW Sbjct: 80 KNGIKVEAFASLA----PW 94 >UniRef50_P91997 Cluster: Putative uncharacterized protein; n=4; Caenorhabditis|Rep: Putative uncharacterized protein - Caenorhabditis elegans Length = 297 Score = 64.9 bits (151), Expect = 3e-09 Identities = 34/113 (30%), Positives = 58/113 (51%) Frame = +1 Query: 406 NLNVQYLDLYLIHWPQAYKEDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIG 585 +L Y+D+YL+H+P+ D D ++ + Y + +E G V+SIG Sbjct: 108 SLQTDYIDMYLVHYPKPNDSDN-----DDVNNAEYRKIAY----EVLEEAKAAGKVRSIG 158 Query: 586 VSNFNSKQLERLLQHATVKPVVNQVECHPYLNQKRLKEFCEARGVKITXYSPL 744 VSN+ LE L +A V P NQ+E HP+ + L+++C+ + + +S L Sbjct: 159 VSNYEIVHLEELKTYAKVPPCANQLEYHPHFARIPLQKYCKEKNIFFQAFSSL 211 >UniRef50_A7BA05 Cluster: Putative uncharacterized protein; n=1; Actinomyces odontolyticus ATCC 17982|Rep: Putative uncharacterized protein - Actinomyces odontolyticus ATCC 17982 Length = 292 Score = 64.5 bits (150), Expect = 4e-09 Identities = 34/96 (35%), Positives = 49/96 (51%) Frame = +3 Query: 114 IPVVXFXXGASXPVFGXGXWXSKPGXVXXAVKXAIDIGXRHIDCAYVYGNXXXVGXAITS 293 IP G+ PV G G + P AV A+++G RHID A +YGN VG A Sbjct: 16 IPTFMLPTGSPIPVLGFGTYKVAPEDTYDAVSRALEVGYRHIDTAQMYGNEAEVGAA--- 72 Query: 294 KIKEGVVTRXXLFITSKLWNTFHRPDLVRGALQEXL 401 ++ + R LFIT+K+ N+ H PD +++ L Sbjct: 73 -LEASGIAREDLFITTKVDNSNHEPDRAAASIRRSL 107 Score = 60.5 bits (140), Expect = 6e-08 Identities = 37/122 (30%), Positives = 56/122 (45%) Frame = +1 Query: 379 AVPCRXPWXNLNVQYLDLYLIHWPQAYKEDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLV 558 A R +L Y+DL L+HWP PT G + W A+E Sbjct: 100 AASIRRSLEDLRTDYVDLLLVHWP---------LPTLYGGDVALP-------WPALEDAF 143 Query: 559 KEGLVKSIGVSNFNSKQLERLLQHATVKPVVNQVECHPYLNQKRLKEFCEARGVKITXYS 738 G ++IG+SN+ + +E + + ATV P V QVE HP+ L+ + + G+ +S Sbjct: 144 NAGGARAIGLSNYEREHVEAVREVATVAPHVLQVESHPFFPNADLRAYAQGLGMVFEAWS 203 Query: 739 PL 744 PL Sbjct: 204 PL 205 >UniRef50_Q7VG53 Cluster: Aldo-keto reductase; n=28; Bacteria|Rep: Aldo-keto reductase - Helicobacter hepaticus Length = 292 Score = 64.1 bits (149), Expect = 5e-09 Identities = 37/112 (33%), Positives = 57/112 (50%) Frame = +1 Query: 409 LNVQYLDLYLIHWPQAYKEDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGV 588 + + ++DL LIH PQ + F K + V+ + A+E K G V+SIGV Sbjct: 106 MKLDFIDLMLIHSPQPWNS----FRKGDYFK------ENVEVYNALEDAQKAGKVRSIGV 155 Query: 589 SNFNSKQLERLLQHATVKPVVNQVECHPYLNQKRLKEFCEARGVKITXYSPL 744 SNF K LE +L++ KP NQ+ CH L ++C+ + + YSP+ Sbjct: 156 SNFLQKDLENILKNCKTKPAANQILCHIGNTPFTLLDYCKKQNILAEAYSPI 207 Score = 53.2 bits (122), Expect = 9e-06 Identities = 32/71 (45%), Positives = 36/71 (50%), Gaps = 1/71 (1%) Frame = +3 Query: 138 GASXPVFGXGXWXSKPGXVXXAVKXAIDIGXRHIDCAYVYGNXXXVGXAI-TSKIKEGVV 314 G P G G W V AV+ A +G RHID A YGN VG A+ SKIK Sbjct: 20 GNKIPKLGLGTWRIDDNVVEAAVREAFKVGYRHIDTAQAYGNERGVGEAVRKSKIK---- 75 Query: 315 TRXXLFITSKL 347 R LFITSK+ Sbjct: 76 -REELFITSKI 85 >UniRef50_Q1RFP0 Cluster: 2,5-diketo-D-gluconic acid reductase A; n=21; Bacteria|Rep: 2,5-diketo-D-gluconic acid reductase A - Escherichia coli (strain UTI89 / UPEC) Length = 294 Score = 64.1 bits (149), Expect = 5e-09 Identities = 31/76 (40%), Positives = 42/76 (55%) Frame = +1 Query: 520 DYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQHATVKPVVNQVECHPYLNQKRLKE 699 DY W+A+E +EG +K+IGVSNF L + VKP+VNQVE HPY Q Sbjct: 122 DYFSAWRALEDAYEEGKLKAIGVSNFYPHVLANFCETVRVKPMVNQVELHPYFAQPEALA 181 Query: 700 FCEARGVKITXYSPLG 747 + V+ ++PLG Sbjct: 182 TMKYYNVQPEAWAPLG 197 Score = 55.6 bits (128), Expect = 2e-06 Identities = 35/89 (39%), Positives = 44/89 (49%), Gaps = 2/89 (2%) Frame = +3 Query: 150 PVFGXGXWXSKPGXVXX-AVKXAIDIGXRHIDCAYVYGNXXXVGXAITSKIKEGVVTRXX 326 P+ G G + V +V AI G R ID A VYGN VG A+ I EG+ TR Sbjct: 18 PMMGFGVFQVTDKDVCKQSVLNAIRTGYRLIDTAAVYGNEDAVGEAVREAISEGLCTREE 77 Query: 327 LFITSKLW-NTFHRPDLVRGALQEXLXQS 410 LFITSKLW D+ ++ L +S Sbjct: 78 LFITSKLWVQDMLNQDIAAAGIEASLKKS 106 >UniRef50_Q5KKZ8 Cluster: Aldo-keto reductase, putative; n=2; Filobasidiella neoformans|Rep: Aldo-keto reductase, putative - Cryptococcus neoformans (Filobasidiella neoformans) Length = 293 Score = 64.1 bits (149), Expect = 5e-09 Identities = 31/72 (43%), Positives = 42/72 (58%) Frame = +1 Query: 529 DTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQHATVKPVVNQVECHPYLNQKRLKEFCE 708 + W+A+ KEG VK IGVSNF L+ L P VNQ+E HP+ Q+ + ++CE Sbjct: 129 NNWEALTIAQKEGWVKDIGVSNFGIHHLKALPPPV---PAVNQIELHPFCQQRDIVKYCE 185 Query: 709 ARGVKITXYSPL 744 G+ I YSPL Sbjct: 186 EHGIAIEAYSPL 197 Score = 47.6 bits (108), Expect = 4e-04 Identities = 32/95 (33%), Positives = 46/95 (48%), Gaps = 2/95 (2%) Frame = +3 Query: 138 GASXPVFGXGXWXSKPGXVXXAVKXAIDIGXRHIDCAYVYGNXXXVGXAITSKIKEGVVT 317 G P G G + ++ AVK AID G RH+D A Y N VG A I+ V Sbjct: 14 GNLIPRLGFGVYQARSKECEDAVKKAIDTGYRHVDTAQAYHNEENVGRA----IRNSGVP 69 Query: 318 RXXLFITSKLW--NTFHRPDLVRGALQEXLXQSER 416 R +F+TSK +T + P V +++ L + +R Sbjct: 70 RPSVFLTSKYMPSHTVYSPTEVLDVVRKSLKKVDR 104 >UniRef50_Q9ZUJ6 Cluster: T2K10.1 protein; n=16; core eudicotyledons|Rep: T2K10.1 protein - Arabidopsis thaliana (Mouse-ear cress) Length = 176 Score = 63.7 bits (148), Expect = 6e-09 Identities = 31/69 (44%), Positives = 40/69 (57%) Frame = +1 Query: 406 NLNVQYLDLYLIHWPQAYKEDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIG 585 NL + YLDLY+IHWP + K FP D+ F +D+ W ME + GL K IG Sbjct: 111 NLKLDYLDLYIIHWPVSSKPGKYKFPIDED---DFMPMDFEVVWSEMEECQRLGLAKCIG 167 Query: 586 VSNFNSKQL 612 VSNF+ K+L Sbjct: 168 VSNFSCKKL 176 Score = 42.7 bits (96), Expect = 0.012 Identities = 29/90 (32%), Positives = 42/90 (46%), Gaps = 4/90 (4%) Frame = +3 Query: 144 SXPVFGXGXWXS---KPGXVXXAVKXAIDIGXRHIDCAYVYGNXXXVGXAITSKIKEGVV 314 S PV G G S +P + V AI +G RH D + Y +G A+ + G+V Sbjct: 20 SMPVLGFGTAASPLPEPTMLKETVIEAIKLGYRHFDTSPRYQTEEPIGEALAEAVSLGLV 79 Query: 315 -TRXXLFITSKLWNTFHRPDLVRGALQEXL 401 +R F+T+KLW LV A++ L Sbjct: 80 RSRSEFFVTTKLWCADAHGGLVVPAIKRSL 109 >UniRef50_A7RUA2 Cluster: Predicted protein; n=1; Nematostella vectensis|Rep: Predicted protein - Nematostella vectensis Length = 246 Score = 63.7 bits (148), Expect = 6e-09 Identities = 28/73 (38%), Positives = 44/73 (60%) Frame = +1 Query: 529 DTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQHATVKPVVNQVECHPYLNQKRLKEFCE 708 ++WKAME L ++G ++S+GVSNFN +L+ L+ ATV Q P+ ++ + FC Sbjct: 103 ESWKAMEELHRQGKIRSLGVSNFNVDELQELVNFATVPVSAVQNWFDPFHQDRKARRFCN 162 Query: 709 ARGVKITXYSPLG 747 G++ YS LG Sbjct: 163 KHGIRYIGYSTLG 175 >UniRef50_A7RPK2 Cluster: Predicted protein; n=1; Nematostella vectensis|Rep: Predicted protein - Nematostella vectensis Length = 151 Score = 63.7 bits (148), Expect = 6e-09 Identities = 29/73 (39%), Positives = 43/73 (58%) Frame = +1 Query: 529 DTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQHATVKPVVNQVECHPYLNQKRLKEFCE 708 D+W+A+E LV +G ++SIGVSNF K L++L A V P Q P+ K +++C+ Sbjct: 1 DSWRALEELVSQGKIRSIGVSNFEVKDLKKLKDIAKVPPSAIQNFFTPFYQDKATRQYCK 60 Query: 709 ARGVKITXYSPLG 747 +K YS LG Sbjct: 61 ENNIKYMGYSTLG 73 >UniRef50_Q88SL1 Cluster: Oxidoreductase; n=51; Lactobacillales|Rep: Oxidoreductase - Lactobacillus plantarum Length = 286 Score = 63.3 bits (147), Expect = 8e-09 Identities = 38/114 (33%), Positives = 57/114 (50%) Frame = +1 Query: 409 LNVQYLDLYLIHWPQAYKEDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGV 588 L + Y+DLYLIHWP + + + ++ DTW+AME ++IGV Sbjct: 103 LGLDYVDLYLIHWPNP-----------AAMRDNWEQLN-ADTWRAMEEAYTARKARAIGV 150 Query: 589 SNFNSKQLERLLQHATVKPVVNQVECHPYLNQKRLKEFCEARGVKITXYSPLGS 750 SNF K L+ LL+ A V P VNQ+ +P + + + + YSPLG+ Sbjct: 151 SNFRPKHLDALLKTAKVVPAVNQIFLNPSDMEDEVVAYNRKHDILSEAYSPLGT 204 Score = 62.9 bits (146), Expect = 1e-08 Identities = 36/89 (40%), Positives = 44/89 (49%), Gaps = 1/89 (1%) Frame = +3 Query: 138 GASXPVFGXGXWXSKPGXVXX-AVKXAIDIGXRHIDCAYVYGNXXXVGXAITSKIKEGVV 314 G P+ G G W + G V +V A+ G RHID A YGN VG AI + V Sbjct: 16 GTKIPIVGFGTWQTPDGQVAYDSVLAALKAGYRHIDTAAAYGNEESVGKAIA----DSGV 71 Query: 315 TRXXLFITSKLWNTFHRPDLVRGALQEXL 401 R LF+T+KLWN H D + AL L Sbjct: 72 AREDLFVTTKLWNADHGYDAAKKALDTSL 100 Score = 33.9 bits (74), Expect = 5.7 Identities = 13/32 (40%), Positives = 23/32 (71%) Frame = +2 Query: 800 PKLKXIADRLGKTVAQVLIRYQIDXGXIVXPE 895 P+LK +AD+ K+VAQV++R+ + G + P+ Sbjct: 211 PELKTLADKYDKSVAQVVLRWSLQHGFLPLPK 242 >UniRef50_UPI000023DA24 Cluster: hypothetical protein FG10036.1; n=1; Gibberella zeae PH-1|Rep: hypothetical protein FG10036.1 - Gibberella zeae PH-1 Length = 312 Score = 62.9 bits (146), Expect = 1e-08 Identities = 37/130 (28%), Positives = 66/130 (50%), Gaps = 1/130 (0%) Frame = +1 Query: 409 LNVQYLDLYLIHWPQAYKEDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGV 588 L + +DL ++ +P E + D++ Q + + + TWK E L K+GLVK + V Sbjct: 131 LGITTIDLLIVSFPGISFEGSCEWEADKTNAHQGNLEEELATWKVFESLHKQGLVKRLAV 190 Query: 589 SNFNSKQLERLLQHATVKPVVNQVECHPYLN-QKRLKEFCEARGVKITXYSPLGSPDRPW 765 + F S++L ++H TV+PV++Q+ + LK+ E GV++ ++ + P Sbjct: 191 AEFGSEKLSAFIKHTTVRPVIDQINLRNCCDVPPPLKKLAEDEGVELHVHNDC-TDILPH 249 Query: 766 GQARRPPXHG 795 G R HG Sbjct: 250 GTLRELLSHG 259 >UniRef50_Q88TV9 Cluster: Oxidoreductase; n=4; Lactobacillus|Rep: Oxidoreductase - Lactobacillus plantarum Length = 288 Score = 62.9 bits (146), Expect = 1e-08 Identities = 40/113 (35%), Positives = 56/113 (49%) Frame = +1 Query: 409 LNVQYLDLYLIHWPQAYKEDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGV 588 L + Y+DLYLIH P + DV W+AME K G +KSIGV Sbjct: 99 LRLDYIDLYLIHQP-------------------YGDVP--GAWQAMEAAQKAGKLKSIGV 137 Query: 589 SNFNSKQLERLLQHATVKPVVNQVECHPYLNQKRLKEFCEARGVKITXYSPLG 747 SN ++ + P VNQVE +PY Q+ L++ A+ VK+ ++PLG Sbjct: 138 SNMTPTLWQKFVPQFETIPAVNQVEFNPYFQQQPLRQLLAAQDVKLEAWAPLG 190 Score = 51.6 bits (118), Expect = 3e-05 Identities = 30/79 (37%), Positives = 39/79 (49%), Gaps = 1/79 (1%) Frame = +3 Query: 117 PVVXFXXGASXPVFGXGXWX-SKPGXVXXAVKXAIDIGXRHIDCAYVYGNXXXVGXAITS 293 P + G + P G G + G AVK A+ IG RHID A Y N VG A Sbjct: 5 PTITLNDGRAIPAIGFGTFQIPDDGSTYQAVKEALVIGYRHIDTAVAYFNEDEVGQA--- 61 Query: 294 KIKEGVVTRXXLFITSKLW 350 IK+ + R +++TSKLW Sbjct: 62 -IKDSGIPRDQIWVTSKLW 79 >UniRef50_Q15NA5 Cluster: Aldo/keto reductase; n=2; Gammaproteobacteria|Rep: Aldo/keto reductase - Pseudoalteromonas atlantica (strain T6c / BAA-1087) Length = 273 Score = 62.1 bits (144), Expect = 2e-08 Identities = 37/114 (32%), Positives = 55/114 (48%), Gaps = 1/114 (0%) Frame = +1 Query: 409 LNVQYLDLYLIHWPQAYKEDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGV 588 LN Y+DL L+HWP K+ ++ Y+ KA + + GL + IGV Sbjct: 94 LNTDYVDLLLVHWPSP------------DNKVSMAE--YLKELKACK---ERGLTRHIGV 136 Query: 589 SNFNSKQLERLLQHATVKPVV-NQVECHPYLNQKRLKEFCEARGVKITXYSPLG 747 SNF QL+ L ++ NQ+E HP K L +C+ +++T Y PLG Sbjct: 137 SNFTQSQLDEALSILGKDHILTNQIEVHPNFQNKELVAYCQRNNIQVTAYMPLG 190 Score = 50.4 bits (115), Expect = 6e-05 Identities = 26/67 (38%), Positives = 37/67 (55%) Frame = +3 Query: 150 PVFGXGXWXSKPGXVXXAVKXAIDIGXRHIDCAYVYGNXXXVGXAITSKIKEGVVTRXXL 329 P G G + K AV+ A+D+G RHID A Y N VG AI++ ++R L Sbjct: 12 PTPGFGTYRLKGDDAKLAVENALDVGYRHIDTAQAYENEAEVGDAISA----SKISRGEL 67 Query: 330 FITSKLW 350 F+T+K+W Sbjct: 68 FVTTKVW 74 >UniRef50_Q5UYI9 Cluster: Oxidoreductase; n=1; Haloarcula marismortui|Rep: Oxidoreductase - Haloarcula marismortui (Halobacterium marismortui) Length = 264 Score = 62.1 bits (144), Expect = 2e-08 Identities = 39/120 (32%), Positives = 57/120 (47%) Frame = +1 Query: 388 CRXPWXNLNVQYLDLYLIHWPQAYKEDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEG 567 C L YLDLYL+HWP + + I+ +T AM L +G Sbjct: 73 CEASLDRLGTDYLDLYLVHWP------------NPATSIR-------ETMNAMATLHDQG 113 Query: 568 LVKSIGVSNFNSKQLERLLQHATVKPVVNQVECHPYLNQKRLKEFCEARGVKITXYSPLG 747 ++++GVSNF++ QL A V VNQ+E HP+ Q ++ EFC + +PLG Sbjct: 114 KIRNVGVSNFSAYQLGAAQHVADVPIAVNQIEYHPWNTQDQVVEFCRDTDTVVEAAAPLG 173 Score = 34.3 bits (75), Expect = 4.3 Identities = 19/63 (30%), Positives = 30/63 (47%) Frame = +3 Query: 159 GXGXWXSKPGXVXXAVKXAIDIGXRHIDCAYVYGNXXXVGXAITSKIKEGVVTRXXLFIT 338 G G W V +V+ +++G H+D A Y N +G A+ +E V F+T Sbjct: 3 GVGTWDIDGDTVQKSVRAGLNVGYAHVDTAEGYKNESEIGEALADYDREDV------FLT 56 Query: 339 SKL 347 SK+ Sbjct: 57 SKV 59 >UniRef50_Q5FLI5 Cluster: Aldehyde reductase; n=2; Bacteria|Rep: Aldehyde reductase - Lactobacillus acidophilus Length = 278 Score = 61.7 bits (143), Expect = 2e-08 Identities = 27/74 (36%), Positives = 49/74 (66%) Frame = +1 Query: 520 DYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQHATVKPVVNQVECHPYLNQKRLKE 699 DY TW+A+E L +EG +++IGVS+F +++L L+ VKP VNQ+E + + + + ++ Sbjct: 113 DYYGTWRALERLYQEGRIRAIGVSSFWNERLADLITFNDVKPAVNQIETNVWNQEWKSQQ 172 Query: 700 FCEARGVKITXYSP 741 + E GV+ ++P Sbjct: 173 YMEKEGVQPEAWAP 186 Score = 43.2 bits (97), Expect = 0.009 Identities = 26/77 (33%), Positives = 35/77 (45%), Gaps = 1/77 (1%) Frame = +3 Query: 123 VXFXXGASXPVFGXGXWXSKP-GXVXXAVKXAIDIGXRHIDCAYVYGNXXXVGXAITSKI 299 V G P G G + V+ +++G R +D A +YGN VG AI Sbjct: 5 VTLNNGIKMPRLGFGVYQIDDLAQAQQVVEDGLEVGYRLVDTAQIYGNEQAVGDAI---- 60 Query: 300 KEGVVTRXXLFITSKLW 350 K V R +FITSK+W Sbjct: 61 KHSNVPREDIFITSKIW 77 >UniRef50_Q76L36 Cluster: Conjugated polyketone reductase C2; n=1; Candida parapsilosis|Rep: Conjugated polyketone reductase C2 - Candida parapsilosis (Yeast) Length = 307 Score = 61.7 bits (143), Expect = 2e-08 Identities = 42/117 (35%), Positives = 59/117 (50%), Gaps = 5/117 (4%) Frame = +1 Query: 409 LNVQYLDLYLIHWPQAYKEDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGV 588 L V Y+DL+LIH P F T+Q+ W+A+ K G V+ IG+ Sbjct: 114 LGVDYVDLFLIHSP--------FFTTEQTHGYTLEQA-----WEALVEAKKAGKVREIGI 160 Query: 589 SNFNSKQLERLLQHA---TVKPVVNQVECHPYL-NQ-KRLKEFCEARGVKITXYSPL 744 SN LE+L + PVVNQ+E HP+L NQ K + FC+ G+ + +SPL Sbjct: 161 SNAAIPHLEKLFAASPSPEYYPVVNQIEFHPFLQNQSKNIVRFCQEHGILVEAFSPL 217 >UniRef50_Q0UQ60 Cluster: Putative uncharacterized protein; n=1; Phaeosphaeria nodorum|Rep: Putative uncharacterized protein - Phaeosphaeria nodorum (Septoria nodorum) Length = 225 Score = 61.7 bits (143), Expect = 2e-08 Identities = 31/79 (39%), Positives = 43/79 (54%) Frame = +1 Query: 463 EDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQHATVK 642 E G FP + G D+D T+KA+E L+ G V++IGVSNF L LL ++ Sbjct: 26 ESGEWFPLREDGTFDLVDIDPAITYKAVEKLLLTGKVRAIGVSNFTVNALTDLLSKTSIV 85 Query: 643 PVVNQVECHPYLNQKRLKE 699 PVVNQ+E + L + E Sbjct: 86 PVVNQIEAYSPLGNNQTGE 104 >UniRef50_Q9A2X8 Cluster: Oxidoreductase, aldo/keto reductase family; n=3; Caulobacter|Rep: Oxidoreductase, aldo/keto reductase family - Caulobacter crescentus (Caulobacter vibrioides) Length = 279 Score = 60.9 bits (141), Expect = 4e-08 Identities = 39/112 (34%), Positives = 56/112 (50%) Frame = +1 Query: 409 LNVQYLDLYLIHWPQAYKEDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGV 588 L V +DL L+HWP+ +V +T KA+ + +G ++IG+ Sbjct: 98 LGVDQVDLLLLHWPKP-------------------EVPLAETLKALNAVRAKGWTRAIGL 138 Query: 589 SNFNSKQLERLLQHATVKPVVNQVECHPYLNQKRLKEFCEARGVKITXYSPL 744 SNF S QLE + + +QVE HPYL+ K LK + GV IT +SPL Sbjct: 139 SNFPSAQLEEAAKLSEAPIATDQVEYHPYLSLKTLKAKADQLGVSITAWSPL 190 Score = 58.4 bits (135), Expect = 2e-07 Identities = 32/80 (40%), Positives = 43/80 (53%), Gaps = 1/80 (1%) Frame = +3 Query: 150 PVFGXGXWXSKPGXVXXAVKXAIDIGXRHIDCAYVYGNXXXVGXAITSKIKEGVVTRXXL 329 P G G W + G V+ A++IG RHID A +YGN VG A I+ V R + Sbjct: 16 PALGFGTWQLENGTAVPLVEKALEIGYRHIDTAQIYGNERDVGAA----IRNSGVKRDEI 71 Query: 330 FITSKLW-NTFHRPDLVRGA 386 F+T+K+W + F DL R A Sbjct: 72 FLTTKVWIDQFADGDLQRSA 91 >UniRef50_A0L1A2 Cluster: Aldo/keto reductase; n=8; Gammaproteobacteria|Rep: Aldo/keto reductase - Shewanella sp. (strain ANA-3) Length = 280 Score = 60.9 bits (141), Expect = 4e-08 Identities = 40/112 (35%), Positives = 56/112 (50%), Gaps = 1/112 (0%) Frame = +1 Query: 409 LNVQYLDLYLIHWPQAYKEDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGV 588 L +YLDL LIHWP E S V+Y+ KA ++ +GL + IGV Sbjct: 100 LQTKYLDLLLIHWPLNSDEP--------------SMVEYLSELKA---VLDKGLTRRIGV 142 Query: 589 SNFNSKQLERLLQHATVKPV-VNQVECHPYLNQKRLKEFCEARGVKITXYSP 741 SNF + QL + + + NQVE HPYL +++ +FC V +T Y P Sbjct: 143 SNFTNAQLAQAIAILGEGVIYTNQVEVHPYLINRKVTDFCRQHNVLVTGYMP 194 Score = 50.8 bits (116), Expect = 5e-05 Identities = 27/67 (40%), Positives = 36/67 (53%) Frame = +3 Query: 150 PVFGXGXWXSKPGXVXXAVKXAIDIGXRHIDCAYVYGNXXXVGXAITSKIKEGVVTRXXL 329 P+ G G + K AV A++ G RHID A +YGN VG AI + + R L Sbjct: 18 PMLGTGTFRLKDNAAFDAVLMALEEGSRHIDTAQIYGNEQAVGDAINT----SGIPREEL 73 Query: 330 FITSKLW 350 FIT+K+W Sbjct: 74 FITTKVW 80 >UniRef50_A7PNT1 Cluster: Chromosome chr8 scaffold_23, whole genome shotgun sequence; n=1; Vitis vinifera|Rep: Chromosome chr8 scaffold_23, whole genome shotgun sequence - Vitis vinifera (Grape) Length = 219 Score = 60.9 bits (141), Expect = 4e-08 Identities = 34/79 (43%), Positives = 46/79 (58%) Frame = +1 Query: 409 LNVQYLDLYLIHWPQAYKEDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGV 588 L + ++DLYLIHWP K+ + T IQ D TW+AME L G V++IGV Sbjct: 25 LQLDFIDLYLIHWPVRMKKSSVV--TKPENLIQ---PDIPSTWRAMEALYDSGKVRAIGV 79 Query: 589 SNFNSKQLERLLQHATVKP 645 SN ++K+L LL+ A V P Sbjct: 80 SNLSTKKLGDLLEIARVPP 98 >UniRef50_A7SGW6 Cluster: Predicted protein; n=1; Nematostella vectensis|Rep: Predicted protein - Nematostella vectensis Length = 264 Score = 60.9 bits (141), Expect = 4e-08 Identities = 34/112 (30%), Positives = 59/112 (52%) Frame = +1 Query: 409 LNVQYLDLYLIHWPQAYKEDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGV 588 L++ Y+DL+LIH P + G I + + A+ L +EGL++S+GV Sbjct: 103 LDIGYVDLFLIHTP-------------RPGNI-------IAAYDALLTLKEEGLIRSVGV 142 Query: 589 SNFNSKQLERLLQHATVKPVVNQVECHPYLNQKRLKEFCEARGVKITXYSPL 744 SNF LE L + P +NQ+E +P+ Q+ + ++C G+ + Y+P+ Sbjct: 143 SNFGVHHLEELRKAGCRTPAINQIEINPFWRQEEIIKYCNKHGITVEGYAPV 194 >UniRef50_UPI00005A2CCB Cluster: PREDICTED: similar to Aldose reductase (AR) (Aldehyde reductase); n=1; Canis lupus familiaris|Rep: PREDICTED: similar to Aldose reductase (AR) (Aldehyde reductase) - Canis familiaris Length = 182 Score = 60.5 bits (140), Expect = 6e-08 Identities = 30/75 (40%), Positives = 38/75 (50%) Frame = +3 Query: 138 GASXPVFGXGXWXSKPGXVXXAVKXAIDIGXRHIDCAYVYGNXXXVGXAITSKIKEGVVT 317 G P+ G W S P V AVK +D+G HIDC + N VG A+ K+K V Sbjct: 28 GIKVPIMGLATWKSPPSKVTEAVKVVMDLGYCHIDCTHKLQNKREVGLAVQEKLKGQGVK 87 Query: 318 RXXLFITSKLWNTFH 362 R L I S+L +T H Sbjct: 88 REDLSILSELQHTHH 102 Database: uniref50 Posted date: Oct 5, 2007 11:19 AM Number of letters in database: 575,637,011 Number of sequences in database: 1,657,284 Lambda K H 0.318 0.134 0.401 Gapped Lambda K H 0.279 0.0580 0.190 Matrix: BLOSUM62 Gap Penalties: Existence: 9, Extension: 2 Number of Hits to DB: 781,763,039 Number of Sequences: 1657284 Number of extensions: 15031836 Number of successful extensions: 49935 Number of sequences better than 10.0: 472 Number of HSP's better than 10.0 without gapping: 45272 Number of HSP's successfully gapped in prelim test: 0 Number of HSP's that attempted gapping in prelim test: 0 Number of HSP's gapped (non-prelim): 49442 length of database: 575,637,011 effective HSP length: 100 effective length of database: 409,908,611 effective search space used: 81571813589 frameshift window, decay const: 40, 0.1 T: 12 A: 40 X1: 16 ( 7.3 bits) X2: 37 (14.9 bits) X3: 62 (25.0 bits) S1: 41 (21.7 bits)
- SilkBase 1999-2023 -