Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= MFBP02_F_O16
(901 letters)
Database: human
237,096 sequences; 76,859,062 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
X15414-1|CAA33460.1| 316|Homo sapiens protein ( Human mRNA for ... 163 6e-40
M59783-1|AAA51712.1| 316|Homo sapiens aldose reductase protein. 163 6e-40
M34720-1|AAA35560.1| 316|Homo sapiens protein ( Human aldose re... 163 6e-40
J05474-1|AAA51715.1| 316|Homo sapiens aldose reductase protein. 163 6e-40
J05017-1|AAA51714.1| 316|Homo sapiens ALDR1 protein. 163 6e-40
J04795-1|AAA51713.1| 316|Homo sapiens ALDR1 protein. 163 6e-40
BT019859-1|AAV38662.1| 316|Homo sapiens aldo-keto reductase fam... 163 6e-40
BC010391-1|AAH10391.1| 316|Homo sapiens aldo-keto reductase fam... 163 6e-40
BC000260-1|AAH00260.1| 316|Homo sapiens aldo-keto reductase fam... 163 6e-40
AF328729-1|AAN09721.1| 316|Homo sapiens CTCL tumor antigen HD-C... 163 6e-40
AF032455-1|AAB88851.1| 316|Homo sapiens aldose reductase protein. 163 6e-40
AB209796-1|BAD93033.1| 260|Homo sapiens aldo-keto reductase fam... 163 6e-40
CR542203-1|CAG47000.1| 316|Homo sapiens AKR1B1 protein. 163 1e-39
CR450351-1|CAG29347.1| 316|Homo sapiens AKR1B1 protein. 162 1e-39
BC005387-1|AAH05387.1| 316|Homo sapiens aldo-keto reductase fam... 158 3e-38
U37100-1|AAC17469.1| 316|Homo sapiens aldose reductase-like pep... 156 1e-37
CR541801-1|CAG46600.1| 316|Homo sapiens AKR1B10 protein. 156 1e-37
BT006794-1|AAP35440.1| 316|Homo sapiens aldo-keto reductase fam... 156 1e-37
BC008837-1|AAH08837.1| 316|Homo sapiens aldo-keto reductase fam... 156 1e-37
AF052577-1|AAC36465.1| 316|Homo sapiens aldo-keto reductase pro... 156 1e-37
AF524864-1|AAO13380.1| 316|Homo sapiens aldo-ketoreductase prot... 154 5e-37
J04794-1|AAA51711.1| 325|Homo sapiens ALDR1 protein. 148 3e-35
CR457010-1|CAG33291.1| 325|Homo sapiens AKR1A1 protein. 148 3e-35
BT007003-1|AAP35649.1| 325|Homo sapiens aldo-keto reductase fam... 148 3e-35
BC005394-1|AAH05394.1| 325|Homo sapiens aldo-keto reductase fam... 148 3e-35
BC000670-1|AAH00670.1| 325|Homo sapiens aldo-keto reductase fam... 148 3e-35
AL355480-3|CAI22459.1| 325|Homo sapiens aldo-keto reductase fam... 148 3e-35
AF112485-1|AAF01260.1| 325|Homo sapiens aldehyde reductase prot... 148 3e-35
AF036683-1|AAB92369.1| 325|Homo sapiens aldehyde reductase prot... 148 3e-35
U05861-1|AAA18115.1| 323|Homo sapiens hepatic dihydrodiol dehyd... 131 3e-30
U05684-1|AAA16227.1| 323|Homo sapiens dihydrodiol dehydrogenase... 131 3e-30
M86609-1|AAB02880.1| 323|Homo sapiens dihydrodiol dehydrogenase... 131 3e-30
D26124-1|BAA05121.1| 306|Homo sapiens dihydrodiol dehydrogenase... 131 3e-30
BT007197-1|AAP35861.1| 323|Homo sapiens aldo-keto reductase fam... 131 3e-30
BC040210-1|AAH40210.1| 323|Homo sapiens aldo-keto reductase fam... 131 3e-30
BC020216-1|AAH20216.1| 323|Homo sapiens aldo-keto reductase fam... 131 3e-30
BC015490-1|AAH15490.1| 323|Homo sapiens aldo-keto reductase fam... 131 3e-30
AL713867-3|CAI16410.1| 247|Homo sapiens aldo-keto reductase fam... 131 3e-30
AL713867-2|CAI16409.1| 323|Homo sapiens aldo-keto reductase fam... 131 3e-30
AB032150-1|BAA92886.1| 323|Homo sapiens 20 alph-hydroxysteroid ... 131 3e-30
AB031083-1|BAA92883.1| 323|Homo sapiens 20 alpha-hydroxysteroid... 131 3e-30
S68330-1|AAD14013.1| 323|Homo sapiens chlordecone reductase hom... 130 5e-30
U05598-1|AAA20937.1| 323|Homo sapiens dihydrodiol dehydrogenase... 130 7e-30
BT006653-1|AAP35299.1| 323|Homo sapiens aldo-keto reductase fam... 130 7e-30
BC063574-1|AAH63574.1| 323|Homo sapiens aldo-keto reductase fam... 130 7e-30
BC007024-1|AAH07024.1| 323|Homo sapiens aldo-keto reductase fam... 130 7e-30
AL713867-1|CAI16408.1| 323|Homo sapiens aldo-keto reductase fam... 130 7e-30
AL391427-1|CAI14726.1| 323|Homo sapiens aldo-keto reductase fam... 130 7e-30
AB209017-1|BAD92254.1| 286|Homo sapiens aldo-keto reductase fam... 130 7e-30
AB032153-1|BAA92891.1| 323|Homo sapiens bile acid-binding prote... 130 7e-30
AB031084-1|BAA92884.1| 323|Homo sapiens bile acid-binding prote... 130 7e-30
AB021654-1|BAA36169.1| 323|Homo sapiens DD2/bile acid-binding p... 130 7e-30
L32592-1|AAB38486.1| 323|Homo sapiens dihydrodiol dehydrogenase... 130 9e-30
S68290-1|AAD14012.1| 320|Homo sapiens chlordecone reductase hom... 126 8e-29
D17793-1|BAA04619.2| 325|Homo sapiens KIAA0119 protein. 126 8e-29
DQ269985-1|ABB76132.1| 323|Homo sapiens type II 3a-hydroxystero... 126 8e-29
BT007286-1|AAP35950.1| 323|Homo sapiens aldo-keto reductase fam... 126 8e-29
BC019230-1|AAH19230.1| 323|Homo sapiens aldo-keto reductase fam... 126 8e-29
BC001479-1|AAH01479.1| 323|Homo sapiens aldo-keto reductase fam... 126 8e-29
AL391427-4|CAI14729.1| 323|Homo sapiens aldo-keto reductase fam... 126 8e-29
AF149416-1|AAF07272.2| 323|Homo sapiens 3-alpha hydroxysteroid ... 126 8e-29
AB032157-1|BAA92892.1| 323|Homo sapiens prostaglandin F synthas... 126 8e-29
AB018580-1|BAA88488.1| 323|Homo sapiens hluPGFS protein. 126 8e-29
S68288-1|AAD14011.1| 323|Homo sapiens chlordecone reductase hom... 126 1e-28
L43839-1|AAB41916.1| 323|Homo sapiens 3-alpha-hydroxysteroid de... 126 1e-28
BC002862-1|AAH02862.1| 307|Homo sapiens AKR1CL2 protein protein. 125 2e-28
AF263242-1|AAK58523.1| 320|Homo sapiens aldo-keto reductase loo... 125 2e-28
AB055603-1|BAC54568.1| 307|Homo sapiens aldo-keto reductase rel... 125 2e-28
Z28339-1|CAA82193.1| 326|Homo sapiens delta 4-3-oxosteroid 5 be... 123 1e-27
BC130627-1|AAI30628.1| 326|Homo sapiens aldo-keto reductase fam... 123 1e-27
BC130625-1|AAI30626.1| 326|Homo sapiens aldo-keto reductase fam... 123 1e-27
AF283659-1|AAG39381.1| 326|Homo sapiens 5-beta steroid reductas... 123 1e-27
AB045829-1|BAA99542.1| 323|Homo sapiens 3alpha-hydroxysteroid d... 122 2e-27
S68287-1|AAD14010.1| 323|Homo sapiens chlordecone reductase pro... 122 2e-27
M33375-1|AAA35658.1| 308|Homo sapiens protein ( Human chlordeco... 122 2e-27
D26125-1|BAA05122.1| 321|Homo sapiens 3 alpha-hydroxysteroid/di... 122 2e-27
AL355303-2|CAI14202.1| 323|Homo sapiens aldo-keto reductase fam... 122 2e-27
AB032163-1|BAA92893.1| 323|Homo sapiens dihydrodiol dehydrogena... 122 2e-27
AB031085-1|BAA92885.1| 323|Homo sapiens dihydrodiol dehydrogena... 122 2e-27
BC020744-1|AAH20744.1| 323|Homo sapiens aldo-keto reductase fam... 121 3e-27
AK058142-1|BAB71682.1| 146|Homo sapiens protein ( Homo sapiens ... 105 3e-22
AL355480-2|CAI22458.1| 147|Homo sapiens aldo-keto reductase fam... 93 9e-19
AB040822-1|BAC54567.1| 222|Homo sapiens aldo-keto reductase rel... 89 2e-17
AB040821-1|BAC54566.1| 263|Homo sapiens aldo-keto reductase rel... 89 2e-17
AB040820-1|BAC54565.1| 250|Homo sapiens aldo-keto reductase rel... 89 2e-17
BC101205-1|AAI01206.1| 129|Homo sapiens aldo-keto reductase fam... 76 2e-13
BC101204-1|AAI01205.1| 129|Homo sapiens aldo-keto reductase fam... 76 2e-13
AL391427-2|CAI14727.1| 302|Homo sapiens aldo-keto reductase fam... 76 2e-13
AL355303-1|CAI14201.1| 302|Homo sapiens aldo-keto reductase fam... 76 2e-13
AK131335-1|BAD18494.1| 129|Homo sapiens protein ( Homo sapiens ... 76 2e-13
AB037902-1|BAA92887.1| 130|Homo sapiens truncated aldo-keto red... 75 3e-13
AB028065-1|BAA88489.1| 67|Homo sapiens prostaglandin F synthas... 66 2e-10
L35546-1|AAA65028.1| 274|Homo sapiens gamma-glutamylcysteine sy... 40 0.016
CR541833-1|CAG46632.1| 274|Homo sapiens GCLM protein. 40 0.016
BC041809-1|AAH41809.1| 274|Homo sapiens glutamate-cysteine liga... 40 0.016
AY773965-1|AAV28733.1| 274|Homo sapiens glutamate-cysteine liga... 40 0.016
AL117351-10|CAI22976.1| 274|Homo sapiens glutamate-cysteine lig... 40 0.016
AL049796-2|CAI21813.1| 274|Homo sapiens glutamate-cysteine liga... 40 0.016
BC030254-1|AAH30254.1| 433|Homo sapiens chromosome 20 open read... 35 0.35
AL031658-5|CAI42581.1| 433|Homo sapiens chromosome 20 open read... 35 0.35
AF044961-1|AAC15671.1| 85|Homo sapiens aldose reductase-relate... 35 0.35
AB058756-1|BAB47482.1| 708|Homo sapiens KIAA1853 protein protein. 33 1.1
EF471359-1|ABO86192.1| 270|Homo sapiens MHC class I antigen pro... 32 2.5
U30826-1|AAA93070.1| 272|Homo sapiens SRp40-1 protein. 31 7.5
BT007089-1|AAP35752.1| 272|Homo sapiens splicing factor, argini... 31 7.5
BC040209-1|AAH40209.1| 272|Homo sapiens splicing factor, argini... 31 7.5
BC018823-1|AAH18823.1| 272|Homo sapiens splicing factor, argini... 31 7.5
AY130006-1|AAN05090.1| 90|Homo sapiens MU-MB-2.76 protein. 31 7.5
AB209804-1|BAD93041.1| 326|Homo sapiens CS0DF038YO05 variant pr... 31 7.5
AL162417-13|CAI13418.1| 294|Homo sapiens globoside alpha-1,3-N-... 30 10.0
AK074639-1|BAC11106.1| 294|Homo sapiens 40). protein. 30 10.0
AF117899-1|AAF27280.1| 363|Homo sapiens LDLR-FUT fusion protein... 30 10.0
>X15414-1|CAA33460.1| 316|Homo sapiens protein ( Human mRNA for
aldose reductase (EC 1.1.1.2). ).
Length = 316
Score = 163 bits (397), Expect = 6e-40
Identities = 70/134 (52%), Positives = 94/134 (70%), Gaps = 2/134 (1%)
Frame = +1
Query: 388 CRXPWXNLNVQYLDLYLIHWPQAYKEDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEG 567
C+ +L + YLDLYLIHWP +K FP D+SG + SD + +DTW AME LV EG
Sbjct: 93 CQKTLSDLKLDYLDLYLIHWPTGFKPGKEFFPLDESGNVVPSDTNILDTWAAMEELVDEG 152
Query: 568 LVKSIGVSNFNSKQLERLLQHATV--KPVVNQVECHPYLNQKRLKEFCEARGVKITXYSP 741
LVK+IG+SNFN Q+E +L + KP VNQ+ECHPYL Q++L ++C+++G+ +T YSP
Sbjct: 153 LVKAIGISNFNHLQVEMILNKPGLKYKPAVNQIECHPYLTQEKLIQYCQSKGIVVTAYSP 212
Query: 742 LGSPDRPWGQARRP 783
LGSPDRPW + P
Sbjct: 213 LGSPDRPWAKPEDP 226
Score = 106 bits (255), Expect = 9e-23
Identities = 50/88 (56%), Positives = 58/88 (65%)
Frame = +3
Query: 138 GASXPVFGXGXWXSKPGXVXXAVKXAIDIGXRHIDCAYVYGNXXXVGXAITSKIKEGVVT 317
GA P+ G G W S PG V AVK AID+G RHIDCA+VY N VG AI K++E VV
Sbjct: 10 GAKMPILGLGTWKSPPGQVTEAVKVAIDVGYRHIDCAHVYQNENEVGVAIQEKLREQVVK 69
Query: 318 RXXLFITSKLWNTFHRPDLVRGALQEXL 401
R LFI SKLW T+H LV+GA Q+ L
Sbjct: 70 REELFIVSKLWCTYHEKGLVKGACQKTL 97
Score = 52.0 bits (119), Expect = 3e-06
Identities = 22/45 (48%), Positives = 31/45 (68%)
Frame = +2
Query: 761 PGAKPDDPQXMEDPKLKXIADRLGKTVAQVLIRYQIDXGXIVXPE 895
P AKP+DP +EDP++K IA + KT AQVLIR+ + +V P+
Sbjct: 219 PWAKPEDPSLLEDPRIKAIAAKHNKTTAQVLIRFPMQRNLVVIPK 263
>M59783-1|AAA51712.1| 316|Homo sapiens aldose reductase protein.
Length = 316
Score = 163 bits (397), Expect = 6e-40
Identities = 70/134 (52%), Positives = 94/134 (70%), Gaps = 2/134 (1%)
Frame = +1
Query: 388 CRXPWXNLNVQYLDLYLIHWPQAYKEDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEG 567
C+ +L + YLDLYLIHWP +K FP D+SG + SD + +DTW AME LV EG
Sbjct: 93 CQKTLSDLKLDYLDLYLIHWPTGFKPGKEFFPLDESGNVVPSDTNILDTWAAMEELVDEG 152
Query: 568 LVKSIGVSNFNSKQLERLLQHATV--KPVVNQVECHPYLNQKRLKEFCEARGVKITXYSP 741
LVK+IG+SNFN Q+E +L + KP VNQ+ECHPYL Q++L ++C+++G+ +T YSP
Sbjct: 153 LVKAIGISNFNHLQVEMILNKPGLKYKPAVNQIECHPYLTQEKLIQYCQSKGIVVTAYSP 212
Query: 742 LGSPDRPWGQARRP 783
LGSPDRPW + P
Sbjct: 213 LGSPDRPWAKPEDP 226
Score = 106 bits (255), Expect = 9e-23
Identities = 50/88 (56%), Positives = 58/88 (65%)
Frame = +3
Query: 138 GASXPVFGXGXWXSKPGXVXXAVKXAIDIGXRHIDCAYVYGNXXXVGXAITSKIKEGVVT 317
GA P+ G G W S PG V AVK AID+G RHIDCA+VY N VG AI K++E VV
Sbjct: 10 GAKMPILGLGTWKSPPGQVTEAVKVAIDVGYRHIDCAHVYQNENEVGVAIQEKLREQVVK 69
Query: 318 RXXLFITSKLWNTFHRPDLVRGALQEXL 401
R LFI SKLW T+H LV+GA Q+ L
Sbjct: 70 REELFIVSKLWCTYHEKGLVKGACQKTL 97
Score = 52.0 bits (119), Expect = 3e-06
Identities = 22/45 (48%), Positives = 31/45 (68%)
Frame = +2
Query: 761 PGAKPDDPQXMEDPKLKXIADRLGKTVAQVLIRYQIDXGXIVXPE 895
P AKP+DP +EDP++K IA + KT AQVLIR+ + +V P+
Sbjct: 219 PWAKPEDPSLLEDPRIKAIAAKHNKTTAQVLIRFPMQRNLVVIPK 263
>M34720-1|AAA35560.1| 316|Homo sapiens protein ( Human aldose
reductase mRNA, complete cds. ).
Length = 316
Score = 163 bits (397), Expect = 6e-40
Identities = 70/134 (52%), Positives = 94/134 (70%), Gaps = 2/134 (1%)
Frame = +1
Query: 388 CRXPWXNLNVQYLDLYLIHWPQAYKEDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEG 567
C+ +L + YLDLYLIHWP +K FP D+SG + SD + +DTW AME LV EG
Sbjct: 93 CQKTLSDLKLDYLDLYLIHWPTGFKPGKEFFPLDESGNVVPSDTNILDTWAAMEELVDEG 152
Query: 568 LVKSIGVSNFNSKQLERLLQHATV--KPVVNQVECHPYLNQKRLKEFCEARGVKITXYSP 741
LVK+IG+SNFN Q+E +L + KP VNQ+ECHPYL Q++L ++C+++G+ +T YSP
Sbjct: 153 LVKAIGISNFNHLQVEMILNKPGLKYKPAVNQIECHPYLTQEKLIQYCQSKGIVVTAYSP 212
Query: 742 LGSPDRPWGQARRP 783
LGSPDRPW + P
Sbjct: 213 LGSPDRPWAKPEDP 226
Score = 106 bits (255), Expect = 9e-23
Identities = 50/88 (56%), Positives = 58/88 (65%)
Frame = +3
Query: 138 GASXPVFGXGXWXSKPGXVXXAVKXAIDIGXRHIDCAYVYGNXXXVGXAITSKIKEGVVT 317
GA P+ G G W S PG V AVK AID+G RHIDCA+VY N VG AI K++E VV
Sbjct: 10 GAKMPILGLGTWKSPPGQVTEAVKVAIDVGYRHIDCAHVYQNENEVGVAIQEKLREQVVK 69
Query: 318 RXXLFITSKLWNTFHRPDLVRGALQEXL 401
R LFI SKLW T+H LV+GA Q+ L
Sbjct: 70 REELFIVSKLWCTYHEKGLVKGACQKTL 97
Score = 52.0 bits (119), Expect = 3e-06
Identities = 22/45 (48%), Positives = 31/45 (68%)
Frame = +2
Query: 761 PGAKPDDPQXMEDPKLKXIADRLGKTVAQVLIRYQIDXGXIVXPE 895
P AKP+DP +EDP++K IA + KT AQVLIR+ + +V P+
Sbjct: 219 PWAKPEDPSLLEDPRIKAIAAKHNKTTAQVLIRFPMQRNLVVIPK 263
>J05474-1|AAA51715.1| 316|Homo sapiens aldose reductase protein.
Length = 316
Score = 163 bits (397), Expect = 6e-40
Identities = 70/134 (52%), Positives = 94/134 (70%), Gaps = 2/134 (1%)
Frame = +1
Query: 388 CRXPWXNLNVQYLDLYLIHWPQAYKEDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEG 567
C+ +L + YLDLYLIHWP +K FP D+SG + SD + +DTW AME LV EG
Sbjct: 93 CQKTLSDLKLDYLDLYLIHWPTGFKPGKEFFPLDESGNVVPSDTNILDTWAAMEELVDEG 152
Query: 568 LVKSIGVSNFNSKQLERLLQHATV--KPVVNQVECHPYLNQKRLKEFCEARGVKITXYSP 741
LVK+IG+SNFN Q+E +L + KP VNQ+ECHPYL Q++L ++C+++G+ +T YSP
Sbjct: 153 LVKAIGISNFNHLQVEMILNKPGLKYKPAVNQIECHPYLTQEKLIQYCQSKGIVVTAYSP 212
Query: 742 LGSPDRPWGQARRP 783
LGSPDRPW + P
Sbjct: 213 LGSPDRPWAKPEDP 226
Score = 106 bits (255), Expect = 9e-23
Identities = 50/88 (56%), Positives = 58/88 (65%)
Frame = +3
Query: 138 GASXPVFGXGXWXSKPGXVXXAVKXAIDIGXRHIDCAYVYGNXXXVGXAITSKIKEGVVT 317
GA P+ G G W S PG V AVK AID+G RHIDCA+VY N VG AI K++E VV
Sbjct: 10 GAKMPILGLGTWKSPPGQVTEAVKVAIDVGYRHIDCAHVYQNENEVGVAIQEKLREQVVK 69
Query: 318 RXXLFITSKLWNTFHRPDLVRGALQEXL 401
R LFI SKLW T+H LV+GA Q+ L
Sbjct: 70 REELFIVSKLWCTYHEKGLVKGACQKTL 97
Score = 52.0 bits (119), Expect = 3e-06
Identities = 22/45 (48%), Positives = 31/45 (68%)
Frame = +2
Query: 761 PGAKPDDPQXMEDPKLKXIADRLGKTVAQVLIRYQIDXGXIVXPE 895
P AKP+DP +EDP++K IA + KT AQVLIR+ + +V P+
Sbjct: 219 PWAKPEDPSLLEDPRIKAIAAKHNKTTAQVLIRFPMQRNLVVIPK 263
>J05017-1|AAA51714.1| 316|Homo sapiens ALDR1 protein.
Length = 316
Score = 163 bits (397), Expect = 6e-40
Identities = 70/134 (52%), Positives = 94/134 (70%), Gaps = 2/134 (1%)
Frame = +1
Query: 388 CRXPWXNLNVQYLDLYLIHWPQAYKEDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEG 567
C+ +L + YLDLYLIHWP +K FP D+SG + SD + +DTW AME LV EG
Sbjct: 93 CQKTLSDLKLDYLDLYLIHWPTGFKPGKEFFPLDESGNVVPSDTNILDTWAAMEELVDEG 152
Query: 568 LVKSIGVSNFNSKQLERLLQHATV--KPVVNQVECHPYLNQKRLKEFCEARGVKITXYSP 741
LVK+IG+SNFN Q+E +L + KP VNQ+ECHPYL Q++L ++C+++G+ +T YSP
Sbjct: 153 LVKAIGISNFNHLQVEMILNKPGLKYKPAVNQIECHPYLTQEKLIQYCQSKGIVVTAYSP 212
Query: 742 LGSPDRPWGQARRP 783
LGSPDRPW + P
Sbjct: 213 LGSPDRPWAKPEDP 226
Score = 106 bits (255), Expect = 9e-23
Identities = 50/88 (56%), Positives = 58/88 (65%)
Frame = +3
Query: 138 GASXPVFGXGXWXSKPGXVXXAVKXAIDIGXRHIDCAYVYGNXXXVGXAITSKIKEGVVT 317
GA P+ G G W S PG V AVK AID+G RHIDCA+VY N VG AI K++E VV
Sbjct: 10 GAKMPILGLGTWKSPPGQVTEAVKVAIDVGYRHIDCAHVYQNENEVGVAIQEKLREQVVK 69
Query: 318 RXXLFITSKLWNTFHRPDLVRGALQEXL 401
R LFI SKLW T+H LV+GA Q+ L
Sbjct: 70 REELFIVSKLWCTYHEKGLVKGACQKTL 97
Score = 52.0 bits (119), Expect = 3e-06
Identities = 22/45 (48%), Positives = 31/45 (68%)
Frame = +2
Query: 761 PGAKPDDPQXMEDPKLKXIADRLGKTVAQVLIRYQIDXGXIVXPE 895
P AKP+DP +EDP++K IA + KT AQVLIR+ + +V P+
Sbjct: 219 PWAKPEDPSLLEDPRIKAIAAKHNKTTAQVLIRFPMQRNLVVIPK 263
>J04795-1|AAA51713.1| 316|Homo sapiens ALDR1 protein.
Length = 316
Score = 163 bits (397), Expect = 6e-40
Identities = 70/134 (52%), Positives = 94/134 (70%), Gaps = 2/134 (1%)
Frame = +1
Query: 388 CRXPWXNLNVQYLDLYLIHWPQAYKEDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEG 567
C+ +L + YLDLYLIHWP +K FP D+SG + SD + +DTW AME LV EG
Sbjct: 93 CQKTLSDLKLDYLDLYLIHWPTGFKPGKEFFPLDESGNVVPSDTNILDTWAAMEELVDEG 152
Query: 568 LVKSIGVSNFNSKQLERLLQHATV--KPVVNQVECHPYLNQKRLKEFCEARGVKITXYSP 741
LVK+IG+SNFN Q+E +L + KP VNQ+ECHPYL Q++L ++C+++G+ +T YSP
Sbjct: 153 LVKAIGISNFNHLQVEMILNKPGLKYKPAVNQIECHPYLTQEKLIQYCQSKGIVVTAYSP 212
Query: 742 LGSPDRPWGQARRP 783
LGSPDRPW + P
Sbjct: 213 LGSPDRPWAKPEDP 226
Score = 106 bits (255), Expect = 9e-23
Identities = 50/88 (56%), Positives = 58/88 (65%)
Frame = +3
Query: 138 GASXPVFGXGXWXSKPGXVXXAVKXAIDIGXRHIDCAYVYGNXXXVGXAITSKIKEGVVT 317
GA P+ G G W S PG V AVK AID+G RHIDCA+VY N VG AI K++E VV
Sbjct: 10 GAKMPILGLGTWKSPPGQVTEAVKVAIDVGYRHIDCAHVYQNENEVGVAIQEKLREQVVK 69
Query: 318 RXXLFITSKLWNTFHRPDLVRGALQEXL 401
R LFI SKLW T+H LV+GA Q+ L
Sbjct: 70 REELFIVSKLWCTYHEKGLVKGACQKTL 97
Score = 52.0 bits (119), Expect = 3e-06
Identities = 22/45 (48%), Positives = 31/45 (68%)
Frame = +2
Query: 761 PGAKPDDPQXMEDPKLKXIADRLGKTVAQVLIRYQIDXGXIVXPE 895
P AKP+DP +EDP++K IA + KT AQVLIR+ + +V P+
Sbjct: 219 PWAKPEDPSLLEDPRIKAIAAKHNKTTAQVLIRFPMQRNLVVIPK 263
>BT019859-1|AAV38662.1| 316|Homo sapiens aldo-keto reductase family
1, member B1 (aldose reductase) protein.
Length = 316
Score = 163 bits (397), Expect = 6e-40
Identities = 70/134 (52%), Positives = 94/134 (70%), Gaps = 2/134 (1%)
Frame = +1
Query: 388 CRXPWXNLNVQYLDLYLIHWPQAYKEDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEG 567
C+ +L + YLDLYLIHWP +K FP D+SG + SD + +DTW AME LV EG
Sbjct: 93 CQKTLSDLKLDYLDLYLIHWPTGFKPGKEFFPLDESGNVVPSDTNILDTWAAMEELVDEG 152
Query: 568 LVKSIGVSNFNSKQLERLLQHATV--KPVVNQVECHPYLNQKRLKEFCEARGVKITXYSP 741
LVK+IG+SNFN Q+E +L + KP VNQ+ECHPYL Q++L ++C+++G+ +T YSP
Sbjct: 153 LVKAIGISNFNHLQVEMILNKPGLKYKPAVNQIECHPYLTQEKLIQYCQSKGIVVTAYSP 212
Query: 742 LGSPDRPWGQARRP 783
LGSPDRPW + P
Sbjct: 213 LGSPDRPWAKPEDP 226
Score = 106 bits (255), Expect = 9e-23
Identities = 50/88 (56%), Positives = 58/88 (65%)
Frame = +3
Query: 138 GASXPVFGXGXWXSKPGXVXXAVKXAIDIGXRHIDCAYVYGNXXXVGXAITSKIKEGVVT 317
GA P+ G G W S PG V AVK AID+G RHIDCA+VY N VG AI K++E VV
Sbjct: 10 GAKMPILGLGTWKSPPGQVTEAVKVAIDVGYRHIDCAHVYQNENEVGVAIQEKLREQVVK 69
Query: 318 RXXLFITSKLWNTFHRPDLVRGALQEXL 401
R LFI SKLW T+H LV+GA Q+ L
Sbjct: 70 REELFIVSKLWCTYHEKGLVKGACQKTL 97
Score = 52.0 bits (119), Expect = 3e-06
Identities = 22/45 (48%), Positives = 31/45 (68%)
Frame = +2
Query: 761 PGAKPDDPQXMEDPKLKXIADRLGKTVAQVLIRYQIDXGXIVXPE 895
P AKP+DP +EDP++K IA + KT AQVLIR+ + +V P+
Sbjct: 219 PWAKPEDPSLLEDPRIKAIAAKHNKTTAQVLIRFPMQRNLVVIPK 263
>BC010391-1|AAH10391.1| 316|Homo sapiens aldo-keto reductase family
1, member B1 (aldose reductase) protein.
Length = 316
Score = 163 bits (397), Expect = 6e-40
Identities = 70/134 (52%), Positives = 94/134 (70%), Gaps = 2/134 (1%)
Frame = +1
Query: 388 CRXPWXNLNVQYLDLYLIHWPQAYKEDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEG 567
C+ +L + YLDLYLIHWP +K FP D+SG + SD + +DTW AME LV EG
Sbjct: 93 CQKTLSDLKLDYLDLYLIHWPTGFKPGKEFFPLDESGNVVPSDTNILDTWAAMEELVDEG 152
Query: 568 LVKSIGVSNFNSKQLERLLQHATV--KPVVNQVECHPYLNQKRLKEFCEARGVKITXYSP 741
LVK+IG+SNFN Q+E +L + KP VNQ+ECHPYL Q++L ++C+++G+ +T YSP
Sbjct: 153 LVKAIGISNFNHLQVEMILNKPGLKYKPAVNQIECHPYLTQEKLIQYCQSKGIVVTAYSP 212
Query: 742 LGSPDRPWGQARRP 783
LGSPDRPW + P
Sbjct: 213 LGSPDRPWAKPEDP 226
Score = 106 bits (255), Expect = 9e-23
Identities = 50/88 (56%), Positives = 58/88 (65%)
Frame = +3
Query: 138 GASXPVFGXGXWXSKPGXVXXAVKXAIDIGXRHIDCAYVYGNXXXVGXAITSKIKEGVVT 317
GA P+ G G W S PG V AVK AID+G RHIDCA+VY N VG AI K++E VV
Sbjct: 10 GAKMPILGLGTWKSPPGQVTEAVKVAIDVGYRHIDCAHVYQNENEVGVAIQEKLREQVVK 69
Query: 318 RXXLFITSKLWNTFHRPDLVRGALQEXL 401
R LFI SKLW T+H LV+GA Q+ L
Sbjct: 70 REELFIVSKLWCTYHEKGLVKGACQKTL 97
Score = 52.0 bits (119), Expect = 3e-06
Identities = 22/45 (48%), Positives = 31/45 (68%)
Frame = +2
Query: 761 PGAKPDDPQXMEDPKLKXIADRLGKTVAQVLIRYQIDXGXIVXPE 895
P AKP+DP +EDP++K IA + KT AQVLIR+ + +V P+
Sbjct: 219 PWAKPEDPSLLEDPRIKAIAAKHNKTTAQVLIRFPMQRNLVVIPK 263
>BC000260-1|AAH00260.1| 316|Homo sapiens aldo-keto reductase family
1, member B1 (aldose reductase) protein.
Length = 316
Score = 163 bits (397), Expect = 6e-40
Identities = 70/134 (52%), Positives = 94/134 (70%), Gaps = 2/134 (1%)
Frame = +1
Query: 388 CRXPWXNLNVQYLDLYLIHWPQAYKEDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEG 567
C+ +L + YLDLYLIHWP +K FP D+SG + SD + +DTW AME LV EG
Sbjct: 93 CQKTLSDLKLDYLDLYLIHWPTGFKPGKEFFPLDESGNVVPSDTNILDTWAAMEELVDEG 152
Query: 568 LVKSIGVSNFNSKQLERLLQHATV--KPVVNQVECHPYLNQKRLKEFCEARGVKITXYSP 741
LVK+IG+SNFN Q+E +L + KP VNQ+ECHPYL Q++L ++C+++G+ +T YSP
Sbjct: 153 LVKAIGISNFNHLQVEMILNKPGLKYKPAVNQIECHPYLTQEKLIQYCQSKGIVVTAYSP 212
Query: 742 LGSPDRPWGQARRP 783
LGSPDRPW + P
Sbjct: 213 LGSPDRPWAKPEDP 226
Score = 106 bits (255), Expect = 9e-23
Identities = 50/88 (56%), Positives = 58/88 (65%)
Frame = +3
Query: 138 GASXPVFGXGXWXSKPGXVXXAVKXAIDIGXRHIDCAYVYGNXXXVGXAITSKIKEGVVT 317
GA P+ G G W S PG V AVK AID+G RHIDCA+VY N VG AI K++E VV
Sbjct: 10 GAKMPILGLGTWKSPPGQVTEAVKVAIDVGYRHIDCAHVYQNENEVGVAIQEKLREQVVK 69
Query: 318 RXXLFITSKLWNTFHRPDLVRGALQEXL 401
R LFI SKLW T+H LV+GA Q+ L
Sbjct: 70 REELFIVSKLWCTYHEKGLVKGACQKTL 97
Score = 52.0 bits (119), Expect = 3e-06
Identities = 22/45 (48%), Positives = 31/45 (68%)
Frame = +2
Query: 761 PGAKPDDPQXMEDPKLKXIADRLGKTVAQVLIRYQIDXGXIVXPE 895
P AKP+DP +EDP++K IA + KT AQVLIR+ + +V P+
Sbjct: 219 PWAKPEDPSLLEDPRIKAIAAKHNKTTAQVLIRFPMQRNLVVIPK 263
>AF328729-1|AAN09721.1| 316|Homo sapiens CTCL tumor antigen
HD-CL-07 protein.
Length = 316
Score = 163 bits (397), Expect = 6e-40
Identities = 70/134 (52%), Positives = 94/134 (70%), Gaps = 2/134 (1%)
Frame = +1
Query: 388 CRXPWXNLNVQYLDLYLIHWPQAYKEDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEG 567
C+ +L + YLDLYLIHWP +K FP D+SG + SD + +DTW AME LV EG
Sbjct: 93 CQKTLSDLKLDYLDLYLIHWPTGFKPGKEFFPLDESGNVVPSDTNILDTWAAMEELVDEG 152
Query: 568 LVKSIGVSNFNSKQLERLLQHATV--KPVVNQVECHPYLNQKRLKEFCEARGVKITXYSP 741
LVK+IG+SNFN Q+E +L + KP VNQ+ECHPYL Q++L ++C+++G+ +T YSP
Sbjct: 153 LVKAIGISNFNHLQVEMILNKPGLKYKPAVNQIECHPYLTQEKLIQYCQSKGIVVTAYSP 212
Query: 742 LGSPDRPWGQARRP 783
LGSPDRPW + P
Sbjct: 213 LGSPDRPWAKPEDP 226
Score = 106 bits (255), Expect = 9e-23
Identities = 50/88 (56%), Positives = 58/88 (65%)
Frame = +3
Query: 138 GASXPVFGXGXWXSKPGXVXXAVKXAIDIGXRHIDCAYVYGNXXXVGXAITSKIKEGVVT 317
GA P+ G G W S PG V AVK AID+G RHIDCA+VY N VG AI K++E VV
Sbjct: 10 GAKMPILGLGTWKSPPGQVTEAVKVAIDVGYRHIDCAHVYQNENEVGVAIQEKLREQVVK 69
Query: 318 RXXLFITSKLWNTFHRPDLVRGALQEXL 401
R LFI SKLW T+H LV+GA Q+ L
Sbjct: 70 REELFIVSKLWCTYHEKGLVKGACQKTL 97
Score = 52.0 bits (119), Expect = 3e-06
Identities = 22/45 (48%), Positives = 31/45 (68%)
Frame = +2
Query: 761 PGAKPDDPQXMEDPKLKXIADRLGKTVAQVLIRYQIDXGXIVXPE 895
P AKP+DP +EDP++K IA + KT AQVLIR+ + +V P+
Sbjct: 219 PWAKPEDPSLLEDPRIKAIAAKHNKTTAQVLIRFPMQRNLVVIPK 263
>AF032455-1|AAB88851.1| 316|Homo sapiens aldose reductase protein.
Length = 316
Score = 163 bits (397), Expect = 6e-40
Identities = 70/134 (52%), Positives = 94/134 (70%), Gaps = 2/134 (1%)
Frame = +1
Query: 388 CRXPWXNLNVQYLDLYLIHWPQAYKEDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEG 567
C+ +L + YLDLYLIHWP +K FP D+SG + SD + +DTW AME LV EG
Sbjct: 93 CQKTLSDLKLDYLDLYLIHWPTGFKPGKEFFPLDESGNVVPSDTNILDTWAAMEELVDEG 152
Query: 568 LVKSIGVSNFNSKQLERLLQHATV--KPVVNQVECHPYLNQKRLKEFCEARGVKITXYSP 741
LVK+IG+SNFN Q+E +L + KP VNQ+ECHPYL Q++L ++C+++G+ +T YSP
Sbjct: 153 LVKAIGISNFNHLQVEMILNKPGLKYKPAVNQIECHPYLTQEKLIQYCQSKGIVVTAYSP 212
Query: 742 LGSPDRPWGQARRP 783
LGSPDRPW + P
Sbjct: 213 LGSPDRPWAKPEDP 226
Score = 106 bits (255), Expect = 9e-23
Identities = 50/88 (56%), Positives = 58/88 (65%)
Frame = +3
Query: 138 GASXPVFGXGXWXSKPGXVXXAVKXAIDIGXRHIDCAYVYGNXXXVGXAITSKIKEGVVT 317
GA P+ G G W S PG V AVK AID+G RHIDCA+VY N VG AI K++E VV
Sbjct: 10 GAKMPILGLGTWKSPPGQVTEAVKVAIDVGYRHIDCAHVYQNENEVGVAIQEKLREQVVK 69
Query: 318 RXXLFITSKLWNTFHRPDLVRGALQEXL 401
R LFI SKLW T+H LV+GA Q+ L
Sbjct: 70 REELFIVSKLWCTYHEKGLVKGACQKTL 97
Score = 52.0 bits (119), Expect = 3e-06
Identities = 22/45 (48%), Positives = 31/45 (68%)
Frame = +2
Query: 761 PGAKPDDPQXMEDPKLKXIADRLGKTVAQVLIRYQIDXGXIVXPE 895
P AKP+DP +EDP++K IA + KT AQVLIR+ + +V P+
Sbjct: 219 PWAKPEDPSLLEDPRIKAIAAKHNKTTAQVLIRFPMQRNLVVIPK 263
>AB209796-1|BAD93033.1| 260|Homo sapiens aldo-keto reductase family
1, member B1 variant protein.
Length = 260
Score = 163 bits (397), Expect = 6e-40
Identities = 70/134 (52%), Positives = 94/134 (70%), Gaps = 2/134 (1%)
Frame = +1
Query: 388 CRXPWXNLNVQYLDLYLIHWPQAYKEDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEG 567
C+ +L + YLDLYLIHWP +K FP D+SG + SD + +DTW AME LV EG
Sbjct: 90 CQKTLSDLKLDYLDLYLIHWPTGFKPGKEFFPLDESGNVVPSDTNILDTWAAMEELVDEG 149
Query: 568 LVKSIGVSNFNSKQLERLLQHATV--KPVVNQVECHPYLNQKRLKEFCEARGVKITXYSP 741
LVK+IG+SNFN Q+E +L + KP VNQ+ECHPYL Q++L ++C+++G+ +T YSP
Sbjct: 150 LVKAIGISNFNHLQVEMILNKPGLKYKPAVNQIECHPYLTQEKLIQYCQSKGIVVTAYSP 209
Query: 742 LGSPDRPWGQARRP 783
LGSPDRPW + P
Sbjct: 210 LGSPDRPWAKPEDP 223
Score = 106 bits (255), Expect = 9e-23
Identities = 50/88 (56%), Positives = 58/88 (65%)
Frame = +3
Query: 138 GASXPVFGXGXWXSKPGXVXXAVKXAIDIGXRHIDCAYVYGNXXXVGXAITSKIKEGVVT 317
GA P+ G G W S PG V AVK AID+G RHIDCA+VY N VG AI K++E VV
Sbjct: 7 GAKMPILGLGTWKSPPGQVTEAVKVAIDVGYRHIDCAHVYQNENEVGVAIQEKLREQVVK 66
Query: 318 RXXLFITSKLWNTFHRPDLVRGALQEXL 401
R LFI SKLW T+H LV+GA Q+ L
Sbjct: 67 REELFIVSKLWCTYHEKGLVKGACQKTL 94
Score = 40.7 bits (91), Expect = 0.007
Identities = 17/30 (56%), Positives = 22/30 (73%)
Frame = +2
Query: 761 PGAKPDDPQXMEDPKLKXIADRLGKTVAQV 850
P AKP+DP +EDP++K IA + KT AQV
Sbjct: 216 PWAKPEDPSLLEDPRIKAIAAKHNKTTAQV 245
>CR542203-1|CAG47000.1| 316|Homo sapiens AKR1B1 protein.
Length = 316
Score = 163 bits (395), Expect = 1e-39
Identities = 70/134 (52%), Positives = 94/134 (70%), Gaps = 2/134 (1%)
Frame = +1
Query: 388 CRXPWXNLNVQYLDLYLIHWPQAYKEDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEG 567
C+ +L + YLDLYLIHWP +K FP D+SG + SD + +DTW AME LV EG
Sbjct: 93 CQKTLSDLKLDYLDLYLIHWPIGFKPGKEFFPLDESGNVVPSDTNILDTWAAMEELVDEG 152
Query: 568 LVKSIGVSNFNSKQLERLLQHATV--KPVVNQVECHPYLNQKRLKEFCEARGVKITXYSP 741
LVK+IG+SNFN Q+E +L + KP VNQ+ECHPYL Q++L ++C+++G+ +T YSP
Sbjct: 153 LVKAIGISNFNHLQVEMILNKPGLKYKPAVNQIECHPYLTQEKLIQYCQSKGIVVTAYSP 212
Query: 742 LGSPDRPWGQARRP 783
LGSPDRPW + P
Sbjct: 213 LGSPDRPWAKPEDP 226
Score = 106 bits (255), Expect = 9e-23
Identities = 50/88 (56%), Positives = 58/88 (65%)
Frame = +3
Query: 138 GASXPVFGXGXWXSKPGXVXXAVKXAIDIGXRHIDCAYVYGNXXXVGXAITSKIKEGVVT 317
GA P+ G G W S PG V AVK AID+G RHIDCA+VY N VG AI K++E VV
Sbjct: 10 GAKMPILGLGTWKSPPGQVTEAVKVAIDVGYRHIDCAHVYQNENEVGVAIQEKLREQVVK 69
Query: 318 RXXLFITSKLWNTFHRPDLVRGALQEXL 401
R LFI SKLW T+H LV+GA Q+ L
Sbjct: 70 REELFIVSKLWCTYHEKGLVKGACQKTL 97
Score = 52.0 bits (119), Expect = 3e-06
Identities = 22/45 (48%), Positives = 31/45 (68%)
Frame = +2
Query: 761 PGAKPDDPQXMEDPKLKXIADRLGKTVAQVLIRYQIDXGXIVXPE 895
P AKP+DP +EDP++K IA + KT AQVLIR+ + +V P+
Sbjct: 219 PWAKPEDPSLLEDPRIKAIAAKHNKTTAQVLIRFPMQRNLVVIPK 263
>CR450351-1|CAG29347.1| 316|Homo sapiens AKR1B1 protein.
Length = 316
Score = 162 bits (394), Expect = 1e-39
Identities = 69/134 (51%), Positives = 94/134 (70%), Gaps = 2/134 (1%)
Frame = +1
Query: 388 CRXPWXNLNVQYLDLYLIHWPQAYKEDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEG 567
C+ +L + YLDLYLIHWP ++ FP D+SG + SD + +DTW AME LV EG
Sbjct: 93 CQKTLSDLKLDYLDLYLIHWPTGFRPGKEFFPLDESGNVVPSDTNILDTWAAMEELVDEG 152
Query: 568 LVKSIGVSNFNSKQLERLLQHATV--KPVVNQVECHPYLNQKRLKEFCEARGVKITXYSP 741
LVK+IG+SNFN Q+E +L + KP VNQ+ECHPYL Q++L ++C+++G+ +T YSP
Sbjct: 153 LVKAIGISNFNHLQVEMILSKPGLKYKPAVNQIECHPYLTQEKLIQYCQSKGIVVTAYSP 212
Query: 742 LGSPDRPWGQARRP 783
LGSPDRPW + P
Sbjct: 213 LGSPDRPWAKPEDP 226
Score = 106 bits (255), Expect = 9e-23
Identities = 50/88 (56%), Positives = 58/88 (65%)
Frame = +3
Query: 138 GASXPVFGXGXWXSKPGXVXXAVKXAIDIGXRHIDCAYVYGNXXXVGXAITSKIKEGVVT 317
GA P+ G G W S PG V AVK AID+G RHIDCA+VY N VG AI K++E VV
Sbjct: 10 GAKMPILGLGTWKSPPGQVTEAVKVAIDVGYRHIDCAHVYQNENEVGVAIQEKLREQVVK 69
Query: 318 RXXLFITSKLWNTFHRPDLVRGALQEXL 401
R LFI SKLW T+H LV+GA Q+ L
Sbjct: 70 REELFIVSKLWCTYHEKGLVKGACQKTL 97
Score = 52.0 bits (119), Expect = 3e-06
Identities = 22/45 (48%), Positives = 31/45 (68%)
Frame = +2
Query: 761 PGAKPDDPQXMEDPKLKXIADRLGKTVAQVLIRYQIDXGXIVXPE 895
P AKP+DP +EDP++K IA + KT AQVLIR+ + +V P+
Sbjct: 219 PWAKPEDPSLLEDPRIKAIAAKHNKTTAQVLIRFPMQRNLVVIPK 263
>BC005387-1|AAH05387.1| 316|Homo sapiens aldo-keto reductase family
1, member B1 (aldose reductase) protein.
Length = 316
Score = 158 bits (383), Expect = 3e-38
Identities = 69/134 (51%), Positives = 93/134 (69%), Gaps = 2/134 (1%)
Frame = +1
Query: 388 CRXPWXNLNVQYLDLYLIHWPQAYKEDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEG 567
C+ +L + YLDLYLIHWP +K FP D+SG + SD + +DT AME LV EG
Sbjct: 93 CQKTLSDLKLDYLDLYLIHWPTGFKPGKEFFPLDESGNVVPSDTNILDTRAAMEELVDEG 152
Query: 568 LVKSIGVSNFNSKQLERLLQHATV--KPVVNQVECHPYLNQKRLKEFCEARGVKITXYSP 741
LVK+IG+SNFN Q+E +L + KP VNQ+ECHPYL Q++L ++C+++G+ +T YSP
Sbjct: 153 LVKAIGISNFNHLQVEMILNKPGLKYKPAVNQIECHPYLTQEKLIQYCQSKGIVVTAYSP 212
Query: 742 LGSPDRPWGQARRP 783
LGSPDRPW + P
Sbjct: 213 LGSPDRPWAKPEDP 226
Score = 106 bits (255), Expect = 9e-23
Identities = 50/88 (56%), Positives = 58/88 (65%)
Frame = +3
Query: 138 GASXPVFGXGXWXSKPGXVXXAVKXAIDIGXRHIDCAYVYGNXXXVGXAITSKIKEGVVT 317
GA P+ G G W S PG V AVK AID+G RHIDCA+VY N VG AI K++E VV
Sbjct: 10 GAKMPILGLGTWKSPPGQVTEAVKVAIDVGYRHIDCAHVYQNENEVGVAIQEKLREQVVK 69
Query: 318 RXXLFITSKLWNTFHRPDLVRGALQEXL 401
R LFI SKLW T+H LV+GA Q+ L
Sbjct: 70 REELFIVSKLWCTYHEKGLVKGACQKTL 97
Score = 52.0 bits (119), Expect = 3e-06
Identities = 22/45 (48%), Positives = 31/45 (68%)
Frame = +2
Query: 761 PGAKPDDPQXMEDPKLKXIADRLGKTVAQVLIRYQIDXGXIVXPE 895
P AKP+DP +EDP++K IA + KT AQVLIR+ + +V P+
Sbjct: 219 PWAKPEDPSLLEDPRIKAIAAKHNKTTAQVLIRFPMQRNLVVIPK 263
>U37100-1|AAC17469.1| 316|Homo sapiens aldose reductase-like
peptide protein.
Length = 316
Score = 156 bits (378), Expect = 1e-37
Identities = 67/128 (52%), Positives = 89/128 (69%), Gaps = 2/128 (1%)
Frame = +1
Query: 406 NLNVQYLDLYLIHWPQAYKEDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIG 585
+L + YLD+YLIHWPQ +K LFP D G ++D W+AME LV EGLVK++G
Sbjct: 99 DLKLSYLDVYLIHWPQGFKSGDDLFPKDDKGNAIGGKATFLDAWEAMEELVDEGLVKALG 158
Query: 586 VSNFNSKQLERLLQHATV--KPVVNQVECHPYLNQKRLKEFCEARGVKITXYSPLGSPDR 759
VSNF+ Q+E+LL + KPV NQVECHPYL Q++L ++C ++G+ +T YSPLGSPDR
Sbjct: 159 VSNFSHFQIEKLLNKPGLKYKPVTNQVECHPYLTQEKLIQYCHSKGITVTAYSPLGSPDR 218
Query: 760 PWGQARRP 783
PW + P
Sbjct: 219 PWAKPEDP 226
Score = 95.1 bits (226), Expect = 3e-19
Identities = 50/95 (52%), Positives = 55/95 (57%)
Frame = +3
Query: 141 ASXPVFGXGXWXSKPGXVXXAVKXAIDIGXRHIDCAYVYGNXXXVGXAITSKIKEGVVTR 320
A P+ G G W S G V AVK AID G RHIDCAYVY N VG AI KI+E V R
Sbjct: 11 AKMPIVGLGTWKSPLGKVKEAVKVAIDAGYRHIDCAYVYQNEHEVGEAIQEKIQEKAVKR 70
Query: 321 XXLFITSKLWNTFHRPDLVRGALQEXLXQSERSVL 425
LFI SKLW TF LVR A ++ L + S L
Sbjct: 71 EDLFIVSKLWPTFFERPLVRKAFEKTLKDLKLSYL 105
Score = 54.4 bits (125), Expect = 5e-07
Identities = 25/45 (55%), Positives = 31/45 (68%)
Frame = +2
Query: 761 PGAKPDDPQXMEDPKLKXIADRLGKTVAQVLIRYQIDXGXIVXPE 895
P AKP+DP +EDPK+K IA + KT AQVLIR+ I IV P+
Sbjct: 219 PWAKPEDPSLLEDPKIKEIAAKHKKTAAQVLIRFHIQRNVIVIPK 263
>CR541801-1|CAG46600.1| 316|Homo sapiens AKR1B10 protein.
Length = 316
Score = 156 bits (378), Expect = 1e-37
Identities = 67/128 (52%), Positives = 89/128 (69%), Gaps = 2/128 (1%)
Frame = +1
Query: 406 NLNVQYLDLYLIHWPQAYKEDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIG 585
+L + YLD+YLIHWPQ +K LFP D G ++D W+AME LV EGLVK++G
Sbjct: 99 DLKLSYLDVYLIHWPQGFKSGDDLFPKDDKGNAIGGKATFLDAWEAMEELVDEGLVKALG 158
Query: 586 VSNFNSKQLERLLQHATV--KPVVNQVECHPYLNQKRLKEFCEARGVKITXYSPLGSPDR 759
VSNF+ Q+E+LL + KPV NQVECHPYL Q++L ++C ++G+ +T YSPLGSPDR
Sbjct: 159 VSNFSHFQIEKLLNKPGLKYKPVTNQVECHPYLTQEKLIQYCHSKGITVTAYSPLGSPDR 218
Query: 760 PWGQARRP 783
PW + P
Sbjct: 219 PWAKPEDP 226
Score = 95.1 bits (226), Expect = 3e-19
Identities = 50/95 (52%), Positives = 55/95 (57%)
Frame = +3
Query: 141 ASXPVFGXGXWXSKPGXVXXAVKXAIDIGXRHIDCAYVYGNXXXVGXAITSKIKEGVVTR 320
A P+ G G W S G V AVK AID G RHIDCAYVY N VG AI KI+E V R
Sbjct: 11 AKMPIVGLGTWKSPLGKVKEAVKVAIDAGYRHIDCAYVYQNEHEVGEAIQEKIQEKAVKR 70
Query: 321 XXLFITSKLWNTFHRPDLVRGALQEXLXQSERSVL 425
LFI SKLW TF LVR A ++ L + S L
Sbjct: 71 EDLFIVSKLWPTFFERPLVRKAFEKTLKDLKLSYL 105
Score = 54.4 bits (125), Expect = 5e-07
Identities = 25/45 (55%), Positives = 31/45 (68%)
Frame = +2
Query: 761 PGAKPDDPQXMEDPKLKXIADRLGKTVAQVLIRYQIDXGXIVXPE 895
P AKP+DP +EDPK+K IA + KT AQVLIR+ I IV P+
Sbjct: 219 PWAKPEDPSLLEDPKIKEIAAKHKKTAAQVLIRFHIQRNVIVIPK 263
>BT006794-1|AAP35440.1| 316|Homo sapiens aldo-keto reductase family
1, member B10 (aldose reductase) protein.
Length = 316
Score = 156 bits (378), Expect = 1e-37
Identities = 67/128 (52%), Positives = 89/128 (69%), Gaps = 2/128 (1%)
Frame = +1
Query: 406 NLNVQYLDLYLIHWPQAYKEDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIG 585
+L + YLD+YLIHWPQ +K LFP D G ++D W+AME LV EGLVK++G
Sbjct: 99 DLKLSYLDVYLIHWPQGFKSGDDLFPKDDKGNAIGGKATFLDAWEAMEELVDEGLVKALG 158
Query: 586 VSNFNSKQLERLLQHATV--KPVVNQVECHPYLNQKRLKEFCEARGVKITXYSPLGSPDR 759
VSNF+ Q+E+LL + KPV NQVECHPYL Q++L ++C ++G+ +T YSPLGSPDR
Sbjct: 159 VSNFSHFQIEKLLNKPGLKYKPVTNQVECHPYLTQEKLIQYCHSKGITVTAYSPLGSPDR 218
Query: 760 PWGQARRP 783
PW + P
Sbjct: 219 PWAKPEDP 226
Score = 95.1 bits (226), Expect = 3e-19
Identities = 50/95 (52%), Positives = 55/95 (57%)
Frame = +3
Query: 141 ASXPVFGXGXWXSKPGXVXXAVKXAIDIGXRHIDCAYVYGNXXXVGXAITSKIKEGVVTR 320
A P+ G G W S G V AVK AID G RHIDCAYVY N VG AI KI+E V R
Sbjct: 11 AKMPIVGLGTWKSPLGKVKEAVKVAIDAGYRHIDCAYVYQNEHEVGEAIQEKIQEKAVKR 70
Query: 321 XXLFITSKLWNTFHRPDLVRGALQEXLXQSERSVL 425
LFI SKLW TF LVR A ++ L + S L
Sbjct: 71 EDLFIVSKLWPTFFERPLVRKAFEKTLKDLKLSYL 105
Score = 54.4 bits (125), Expect = 5e-07
Identities = 25/45 (55%), Positives = 31/45 (68%)
Frame = +2
Query: 761 PGAKPDDPQXMEDPKLKXIADRLGKTVAQVLIRYQIDXGXIVXPE 895
P AKP+DP +EDPK+K IA + KT AQVLIR+ I IV P+
Sbjct: 219 PWAKPEDPSLLEDPKIKEIAAKHKKTAAQVLIRFHIQRNVIVIPK 263
>BC008837-1|AAH08837.1| 316|Homo sapiens aldo-keto reductase family
1, member B10 (aldose reductase) protein.
Length = 316
Score = 156 bits (378), Expect = 1e-37
Identities = 67/128 (52%), Positives = 89/128 (69%), Gaps = 2/128 (1%)
Frame = +1
Query: 406 NLNVQYLDLYLIHWPQAYKEDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIG 585
+L + YLD+YLIHWPQ +K LFP D G ++D W+AME LV EGLVK++G
Sbjct: 99 DLKLSYLDVYLIHWPQGFKSGDDLFPKDDKGNAIGGKATFLDAWEAMEELVDEGLVKALG 158
Query: 586 VSNFNSKQLERLLQHATV--KPVVNQVECHPYLNQKRLKEFCEARGVKITXYSPLGSPDR 759
VSNF+ Q+E+LL + KPV NQVECHPYL Q++L ++C ++G+ +T YSPLGSPDR
Sbjct: 159 VSNFSHFQIEKLLNKPGLKYKPVTNQVECHPYLTQEKLIQYCHSKGITVTAYSPLGSPDR 218
Query: 760 PWGQARRP 783
PW + P
Sbjct: 219 PWAKPEDP 226
Score = 95.1 bits (226), Expect = 3e-19
Identities = 50/95 (52%), Positives = 55/95 (57%)
Frame = +3
Query: 141 ASXPVFGXGXWXSKPGXVXXAVKXAIDIGXRHIDCAYVYGNXXXVGXAITSKIKEGVVTR 320
A P+ G G W S G V AVK AID G RHIDCAYVY N VG AI KI+E V R
Sbjct: 11 AKMPIVGLGTWKSPLGKVKEAVKVAIDAGYRHIDCAYVYQNEHEVGEAIQEKIQEKAVKR 70
Query: 321 XXLFITSKLWNTFHRPDLVRGALQEXLXQSERSVL 425
LFI SKLW TF LVR A ++ L + S L
Sbjct: 71 EDLFIVSKLWPTFFERPLVRKAFEKTLKDLKLSYL 105
Score = 54.4 bits (125), Expect = 5e-07
Identities = 25/45 (55%), Positives = 31/45 (68%)
Frame = +2
Query: 761 PGAKPDDPQXMEDPKLKXIADRLGKTVAQVLIRYQIDXGXIVXPE 895
P AKP+DP +EDPK+K IA + KT AQVLIR+ I IV P+
Sbjct: 219 PWAKPEDPSLLEDPKIKEIAAKHKKTAAQVLIRFHIQRNVIVIPK 263
>AF052577-1|AAC36465.1| 316|Homo sapiens aldo-keto reductase
protein.
Length = 316
Score = 156 bits (378), Expect = 1e-37
Identities = 67/128 (52%), Positives = 89/128 (69%), Gaps = 2/128 (1%)
Frame = +1
Query: 406 NLNVQYLDLYLIHWPQAYKEDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIG 585
+L + YLD+YLIHWPQ +K LFP D G ++D W+AME LV EGLVK++G
Sbjct: 99 DLKLSYLDVYLIHWPQGFKSGDDLFPKDDKGNAIGGKATFLDAWEAMEELVDEGLVKALG 158
Query: 586 VSNFNSKQLERLLQHATV--KPVVNQVECHPYLNQKRLKEFCEARGVKITXYSPLGSPDR 759
VSNF+ Q+E+LL + KPV NQVECHPYL Q++L ++C ++G+ +T YSPLGSPDR
Sbjct: 159 VSNFSHFQIEKLLNKPGLKYKPVTNQVECHPYLTQEKLIQYCHSKGITVTAYSPLGSPDR 218
Query: 760 PWGQARRP 783
PW + P
Sbjct: 219 PWAKPEDP 226
Score = 95.1 bits (226), Expect = 3e-19
Identities = 50/95 (52%), Positives = 55/95 (57%)
Frame = +3
Query: 141 ASXPVFGXGXWXSKPGXVXXAVKXAIDIGXRHIDCAYVYGNXXXVGXAITSKIKEGVVTR 320
A P+ G G W S G V AVK AID G RHIDCAYVY N VG AI KI+E V R
Sbjct: 11 AKMPIVGLGTWKSPLGKVKEAVKVAIDAGYRHIDCAYVYQNEHEVGEAIQEKIQEKAVKR 70
Query: 321 XXLFITSKLWNTFHRPDLVRGALQEXLXQSERSVL 425
LFI SKLW TF LVR A ++ L + S L
Sbjct: 71 EDLFIVSKLWPTFFERPLVRKAFEKTLKDLKLSYL 105
Score = 54.4 bits (125), Expect = 5e-07
Identities = 25/45 (55%), Positives = 31/45 (68%)
Frame = +2
Query: 761 PGAKPDDPQXMEDPKLKXIADRLGKTVAQVLIRYQIDXGXIVXPE 895
P AKP+DP +EDPK+K IA + KT AQVLIR+ I IV P+
Sbjct: 219 PWAKPEDPSLLEDPKIKEIAAKHKKTAAQVLIRFHIQRNVIVIPK 263
>AF524864-1|AAO13380.1| 316|Homo sapiens aldo-ketoreductase
protein.
Length = 316
Score = 154 bits (373), Expect = 5e-37
Identities = 66/125 (52%), Positives = 87/125 (69%), Gaps = 2/125 (1%)
Frame = +1
Query: 415 VQYLDLYLIHWPQAYKEDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSN 594
+ YLD+YLIHWPQ +K LFP D G ++D W+AME LV EGLVK++GVSN
Sbjct: 102 LSYLDVYLIHWPQGFKSGDDLFPKDDKGNAIGGKATFLDAWEAMEELVDEGLVKALGVSN 161
Query: 595 FNSKQLERLLQHATV--KPVVNQVECHPYLNQKRLKEFCEARGVKITXYSPLGSPDRPWG 768
F+ Q+E+LL + KPV NQVECHPYL Q++L ++C ++G+ +T YSPLGSPDRPW
Sbjct: 162 FSHFQIEKLLNKPGLKYKPVTNQVECHPYLTQEKLIQYCHSKGITVTAYSPLGSPDRPWA 221
Query: 769 QARRP 783
+ P
Sbjct: 222 KPEDP 226
Score = 95.5 bits (227), Expect = 2e-19
Identities = 50/95 (52%), Positives = 55/95 (57%)
Frame = +3
Query: 141 ASXPVFGXGXWXSKPGXVXXAVKXAIDIGXRHIDCAYVYGNXXXVGXAITSKIKEGVVTR 320
A P+ G G W S G V AVK AID G RHIDCAYVY N VG AI KI+E V R
Sbjct: 11 AKMPIVGLGTWKSPLGKVKEAVKVAIDAGYRHIDCAYVYQNEHEVGEAIQEKIQEKAVKR 70
Query: 321 XXLFITSKLWNTFHRPDLVRGALQEXLXQSERSVL 425
LFI SKLW TF LVR A ++ L + S L
Sbjct: 71 EDLFIASKLWPTFFERPLVRKAFEKTLKDPKLSYL 105
Score = 54.4 bits (125), Expect = 5e-07
Identities = 25/45 (55%), Positives = 31/45 (68%)
Frame = +2
Query: 761 PGAKPDDPQXMEDPKLKXIADRLGKTVAQVLIRYQIDXGXIVXPE 895
P AKP+DP +EDPK+K IA + KT AQVLIR+ I IV P+
Sbjct: 219 PWAKPEDPSLLEDPKIKEIAAKHKKTAAQVLIRFHIQRNVIVIPK 263
>J04794-1|AAA51711.1| 325|Homo sapiens ALDR1 protein.
Length = 325
Score = 148 bits (358), Expect = 3e-35
Identities = 63/126 (50%), Positives = 89/126 (70%)
Frame = +1
Query: 406 NLNVQYLDLYLIHWPQAYKEDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIG 585
+L ++YLDLYL+HWP A++ + FP + G I + Y +TWKA+E LV +GLV+++G
Sbjct: 101 DLQLEYLDLYLMHWPYAFERGDNPFPKNADGTICYDSTHYKETWKALEALVAKGLVQALG 160
Query: 586 VSNFNSKQLERLLQHATVKPVVNQVECHPYLNQKRLKEFCEARGVKITXYSPLGSPDRPW 765
+SNFNS+Q++ +L A+V+P V QVECHPYL Q L C+ARG+++T YSPLGS DR W
Sbjct: 161 LSNFNSRQIDDILSVASVRPAVLQVECHPYLAQNELIAHCQARGLEVTAYSPLGSSDRAW 220
Query: 766 GQARRP 783
P
Sbjct: 221 RDPDEP 226
Score = 93.5 bits (222), Expect = 9e-19
Identities = 44/94 (46%), Positives = 56/94 (59%), Gaps = 1/94 (1%)
Frame = +3
Query: 123 VXFXXGASXPVFGXGXWXSKPGXVXXAVKXAIDIGXRHIDCAYVYGNXXXVGXAITSKIK 302
V G P+ G G W S+PG V AVK A+ +G RHIDCA +YGN +G A+ +
Sbjct: 6 VLLHTGQKMPLIGLGTWKSEPGQVKAAVKYALSVGYRHIDCAAIYGNEPEIGEALKEDVG 65
Query: 303 EG-VVTRXXLFITSKLWNTFHRPDLVRGALQEXL 401
G V R LF+TSKLWNT H P+ V AL++ L
Sbjct: 66 PGKAVPREELFVTSKLWNTKHHPEDVEPALRKTL 99
Score = 38.7 bits (86), Expect = 0.028
Identities = 14/41 (34%), Positives = 28/41 (68%)
Frame = +2
Query: 773 PDDPQXMEDPKLKXIADRLGKTVAQVLIRYQIDXGXIVXPE 895
PD+P +E+P + +A++ G++ AQ+L+R+Q+ I P+
Sbjct: 223 PDEPVLLEEPVVLALAEKYGRSPAQILLRWQVQRKVICIPK 263
>CR457010-1|CAG33291.1| 325|Homo sapiens AKR1A1 protein.
Length = 325
Score = 148 bits (358), Expect = 3e-35
Identities = 63/126 (50%), Positives = 89/126 (70%)
Frame = +1
Query: 406 NLNVQYLDLYLIHWPQAYKEDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIG 585
+L ++YLDLYL+HWP A++ + FP + G I + Y +TWKA+E LV +GLV+++G
Sbjct: 101 DLQLEYLDLYLMHWPYAFERGDNPFPKNADGTICYDSTHYKETWKALEALVAKGLVQALG 160
Query: 586 VSNFNSKQLERLLQHATVKPVVNQVECHPYLNQKRLKEFCEARGVKITXYSPLGSPDRPW 765
+SNFNS+Q++ +L A+V+P V QVECHPYL Q L C+ARG+++T YSPLGS DR W
Sbjct: 161 LSNFNSRQIDDILSVASVRPAVLQVECHPYLAQNELIAHCQARGLEVTAYSPLGSSDRAW 220
Query: 766 GQARRP 783
P
Sbjct: 221 RDPDEP 226
Score = 93.5 bits (222), Expect = 9e-19
Identities = 44/94 (46%), Positives = 56/94 (59%), Gaps = 1/94 (1%)
Frame = +3
Query: 123 VXFXXGASXPVFGXGXWXSKPGXVXXAVKXAIDIGXRHIDCAYVYGNXXXVGXAITSKIK 302
V G P+ G G W S+PG V AVK A+ +G RHIDCA +YGN +G A+ +
Sbjct: 6 VLLHTGQKMPLIGLGTWKSEPGQVKAAVKYALSVGYRHIDCAAIYGNEPEIGEALKEDVG 65
Query: 303 EG-VVTRXXLFITSKLWNTFHRPDLVRGALQEXL 401
G V R LF+TSKLWNT H P+ V AL++ L
Sbjct: 66 PGKAVPREELFVTSKLWNTKHHPEDVEPALRKTL 99
Score = 38.7 bits (86), Expect = 0.028
Identities = 14/41 (34%), Positives = 28/41 (68%)
Frame = +2
Query: 773 PDDPQXMEDPKLKXIADRLGKTVAQVLIRYQIDXGXIVXPE 895
PD+P +E+P + +A++ G++ AQ+L+R+Q+ I P+
Sbjct: 223 PDEPVLLEEPVVLALAEKYGRSPAQILLRWQVQRKVICIPK 263
>BT007003-1|AAP35649.1| 325|Homo sapiens aldo-keto reductase family
1, member A1 (aldehyde reductase) protein.
Length = 325
Score = 148 bits (358), Expect = 3e-35
Identities = 63/126 (50%), Positives = 89/126 (70%)
Frame = +1
Query: 406 NLNVQYLDLYLIHWPQAYKEDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIG 585
+L ++YLDLYL+HWP A++ + FP + G I + Y +TWKA+E LV +GLV+++G
Sbjct: 101 DLQLEYLDLYLMHWPYAFERGDNPFPKNADGTICYDSTHYKETWKALEALVAKGLVQALG 160
Query: 586 VSNFNSKQLERLLQHATVKPVVNQVECHPYLNQKRLKEFCEARGVKITXYSPLGSPDRPW 765
+SNFNS+Q++ +L A+V+P V QVECHPYL Q L C+ARG+++T YSPLGS DR W
Sbjct: 161 LSNFNSRQIDDILSVASVRPAVLQVECHPYLAQNELIAHCQARGLEVTAYSPLGSSDRAW 220
Query: 766 GQARRP 783
P
Sbjct: 221 RDPDEP 226
Score = 93.5 bits (222), Expect = 9e-19
Identities = 44/94 (46%), Positives = 56/94 (59%), Gaps = 1/94 (1%)
Frame = +3
Query: 123 VXFXXGASXPVFGXGXWXSKPGXVXXAVKXAIDIGXRHIDCAYVYGNXXXVGXAITSKIK 302
V G P+ G G W S+PG V AVK A+ +G RHIDCA +YGN +G A+ +
Sbjct: 6 VLLHTGQKMPLIGLGTWKSEPGQVKAAVKYALSVGYRHIDCAAIYGNEPEIGEALKEDVG 65
Query: 303 EG-VVTRXXLFITSKLWNTFHRPDLVRGALQEXL 401
G V R LF+TSKLWNT H P+ V AL++ L
Sbjct: 66 PGKAVPREELFVTSKLWNTKHHPEDVEPALRKTL 99
Score = 38.7 bits (86), Expect = 0.028
Identities = 14/41 (34%), Positives = 28/41 (68%)
Frame = +2
Query: 773 PDDPQXMEDPKLKXIADRLGKTVAQVLIRYQIDXGXIVXPE 895
PD+P +E+P + +A++ G++ AQ+L+R+Q+ I P+
Sbjct: 223 PDEPVLLEEPVVLALAEKYGRSPAQILLRWQVQRKVICIPK 263
>BC005394-1|AAH05394.1| 325|Homo sapiens aldo-keto reductase family
1, member A1 (aldehyde reductase) protein.
Length = 325
Score = 148 bits (358), Expect = 3e-35
Identities = 63/126 (50%), Positives = 89/126 (70%)
Frame = +1
Query: 406 NLNVQYLDLYLIHWPQAYKEDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIG 585
+L ++YLDLYL+HWP A++ + FP + G I + Y +TWKA+E LV +GLV+++G
Sbjct: 101 DLQLEYLDLYLMHWPYAFERGDNPFPKNADGTICYDSTHYKETWKALEALVAKGLVQALG 160
Query: 586 VSNFNSKQLERLLQHATVKPVVNQVECHPYLNQKRLKEFCEARGVKITXYSPLGSPDRPW 765
+SNFNS+Q++ +L A+V+P V QVECHPYL Q L C+ARG+++T YSPLGS DR W
Sbjct: 161 LSNFNSRQIDDILSVASVRPAVLQVECHPYLAQNELIAHCQARGLEVTAYSPLGSSDRAW 220
Query: 766 GQARRP 783
P
Sbjct: 221 RDPDEP 226
Score = 93.5 bits (222), Expect = 9e-19
Identities = 44/94 (46%), Positives = 56/94 (59%), Gaps = 1/94 (1%)
Frame = +3
Query: 123 VXFXXGASXPVFGXGXWXSKPGXVXXAVKXAIDIGXRHIDCAYVYGNXXXVGXAITSKIK 302
V G P+ G G W S+PG V AVK A+ +G RHIDCA +YGN +G A+ +
Sbjct: 6 VLLHTGQKMPLIGLGTWKSEPGQVKAAVKYALSVGYRHIDCAAIYGNEPEIGEALKEDVG 65
Query: 303 EG-VVTRXXLFITSKLWNTFHRPDLVRGALQEXL 401
G V R LF+TSKLWNT H P+ V AL++ L
Sbjct: 66 PGKAVPREELFVTSKLWNTKHHPEDVEPALRKTL 99
Score = 38.7 bits (86), Expect = 0.028
Identities = 14/41 (34%), Positives = 28/41 (68%)
Frame = +2
Query: 773 PDDPQXMEDPKLKXIADRLGKTVAQVLIRYQIDXGXIVXPE 895
PD+P +E+P + +A++ G++ AQ+L+R+Q+ I P+
Sbjct: 223 PDEPVLLEEPVVLALAEKYGRSPAQILLRWQVQRKVICIPK 263
>BC000670-1|AAH00670.1| 325|Homo sapiens aldo-keto reductase family
1, member A1 (aldehyde reductase) protein.
Length = 325
Score = 148 bits (358), Expect = 3e-35
Identities = 63/126 (50%), Positives = 89/126 (70%)
Frame = +1
Query: 406 NLNVQYLDLYLIHWPQAYKEDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIG 585
+L ++YLDLYL+HWP A++ + FP + G I + Y +TWKA+E LV +GLV+++G
Sbjct: 101 DLQLEYLDLYLMHWPYAFERGDNPFPKNADGTICYDSTHYKETWKALEALVAKGLVQALG 160
Query: 586 VSNFNSKQLERLLQHATVKPVVNQVECHPYLNQKRLKEFCEARGVKITXYSPLGSPDRPW 765
+SNFNS+Q++ +L A+V+P V QVECHPYL Q L C+ARG+++T YSPLGS DR W
Sbjct: 161 LSNFNSRQIDDILSVASVRPAVLQVECHPYLAQNELIAHCQARGLEVTAYSPLGSSDRAW 220
Query: 766 GQARRP 783
P
Sbjct: 221 RDPDEP 226
Score = 93.5 bits (222), Expect = 9e-19
Identities = 44/94 (46%), Positives = 56/94 (59%), Gaps = 1/94 (1%)
Frame = +3
Query: 123 VXFXXGASXPVFGXGXWXSKPGXVXXAVKXAIDIGXRHIDCAYVYGNXXXVGXAITSKIK 302
V G P+ G G W S+PG V AVK A+ +G RHIDCA +YGN +G A+ +
Sbjct: 6 VLLHTGQKMPLIGLGTWKSEPGQVKAAVKYALSVGYRHIDCAAIYGNEPEIGEALKEDVG 65
Query: 303 EG-VVTRXXLFITSKLWNTFHRPDLVRGALQEXL 401
G V R LF+TSKLWNT H P+ V AL++ L
Sbjct: 66 PGKAVPREELFVTSKLWNTKHHPEDVEPALRKTL 99
Score = 38.7 bits (86), Expect = 0.028
Identities = 14/41 (34%), Positives = 28/41 (68%)
Frame = +2
Query: 773 PDDPQXMEDPKLKXIADRLGKTVAQVLIRYQIDXGXIVXPE 895
PD+P +E+P + +A++ G++ AQ+L+R+Q+ I P+
Sbjct: 223 PDEPVLLEEPVVLALAEKYGRSPAQILLRWQVQRKVICIPK 263
>AL355480-3|CAI22459.1| 325|Homo sapiens aldo-keto reductase family
1, member A1 (aldehydetase, 1 protein.
Length = 325
Score = 148 bits (358), Expect = 3e-35
Identities = 63/126 (50%), Positives = 89/126 (70%)
Frame = +1
Query: 406 NLNVQYLDLYLIHWPQAYKEDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIG 585
+L ++YLDLYL+HWP A++ + FP + G I + Y +TWKA+E LV +GLV+++G
Sbjct: 101 DLQLEYLDLYLMHWPYAFERGDNPFPKNADGTICYDSTHYKETWKALEALVAKGLVQALG 160
Query: 586 VSNFNSKQLERLLQHATVKPVVNQVECHPYLNQKRLKEFCEARGVKITXYSPLGSPDRPW 765
+SNFNS+Q++ +L A+V+P V QVECHPYL Q L C+ARG+++T YSPLGS DR W
Sbjct: 161 LSNFNSRQIDDILSVASVRPAVLQVECHPYLAQNELIAHCQARGLEVTAYSPLGSSDRAW 220
Query: 766 GQARRP 783
P
Sbjct: 221 RDPDEP 226
Score = 93.5 bits (222), Expect = 9e-19
Identities = 44/94 (46%), Positives = 56/94 (59%), Gaps = 1/94 (1%)
Frame = +3
Query: 123 VXFXXGASXPVFGXGXWXSKPGXVXXAVKXAIDIGXRHIDCAYVYGNXXXVGXAITSKIK 302
V G P+ G G W S+PG V AVK A+ +G RHIDCA +YGN +G A+ +
Sbjct: 6 VLLHTGQKMPLIGLGTWKSEPGQVKAAVKYALSVGYRHIDCAAIYGNEPEIGEALKEDVG 65
Query: 303 EG-VVTRXXLFITSKLWNTFHRPDLVRGALQEXL 401
G V R LF+TSKLWNT H P+ V AL++ L
Sbjct: 66 PGKAVPREELFVTSKLWNTKHHPEDVEPALRKTL 99
Score = 38.7 bits (86), Expect = 0.028
Identities = 14/41 (34%), Positives = 28/41 (68%)
Frame = +2
Query: 773 PDDPQXMEDPKLKXIADRLGKTVAQVLIRYQIDXGXIVXPE 895
PD+P +E+P + +A++ G++ AQ+L+R+Q+ I P+
Sbjct: 223 PDEPVLLEEPVVLALAEKYGRSPAQILLRWQVQRKVICIPK 263
>AF112485-1|AAF01260.1| 325|Homo sapiens aldehyde reductase
protein.
Length = 325
Score = 148 bits (358), Expect = 3e-35
Identities = 63/126 (50%), Positives = 89/126 (70%)
Frame = +1
Query: 406 NLNVQYLDLYLIHWPQAYKEDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIG 585
+L ++YLDLYL+HWP A++ + FP + G I + Y +TWKA+E LV +GLV+++G
Sbjct: 101 DLQLEYLDLYLMHWPYAFERGDNPFPKNADGTICYDSTHYKETWKALEALVAKGLVQALG 160
Query: 586 VSNFNSKQLERLLQHATVKPVVNQVECHPYLNQKRLKEFCEARGVKITXYSPLGSPDRPW 765
+SNFNS+Q++ +L A+V+P V QVECHPYL Q L C+ARG+++T YSPLGS DR W
Sbjct: 161 LSNFNSRQIDDILSVASVRPAVLQVECHPYLAQNELIAHCQARGLEVTAYSPLGSSDRAW 220
Query: 766 GQARRP 783
P
Sbjct: 221 RDPDEP 226
Score = 93.5 bits (222), Expect = 9e-19
Identities = 44/94 (46%), Positives = 56/94 (59%), Gaps = 1/94 (1%)
Frame = +3
Query: 123 VXFXXGASXPVFGXGXWXSKPGXVXXAVKXAIDIGXRHIDCAYVYGNXXXVGXAITSKIK 302
V G P+ G G W S+PG V AVK A+ +G RHIDCA +YGN +G A+ +
Sbjct: 6 VLLHTGQKMPLIGLGTWKSEPGQVKAAVKYALSVGYRHIDCAAIYGNEPEIGEALKEDVG 65
Query: 303 EG-VVTRXXLFITSKLWNTFHRPDLVRGALQEXL 401
G V R LF+TSKLWNT H P+ V AL++ L
Sbjct: 66 PGKAVPREELFVTSKLWNTKHHPEDVEPALRKTL 99
Score = 38.7 bits (86), Expect = 0.028
Identities = 14/41 (34%), Positives = 28/41 (68%)
Frame = +2
Query: 773 PDDPQXMEDPKLKXIADRLGKTVAQVLIRYQIDXGXIVXPE 895
PD+P +E+P + +A++ G++ AQ+L+R+Q+ I P+
Sbjct: 223 PDEPVLLEEPVVLALAEKYGRSPAQILLRWQVQRKVICIPK 263
>AF036683-1|AAB92369.1| 325|Homo sapiens aldehyde reductase
protein.
Length = 325
Score = 148 bits (358), Expect = 3e-35
Identities = 63/126 (50%), Positives = 89/126 (70%)
Frame = +1
Query: 406 NLNVQYLDLYLIHWPQAYKEDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIG 585
+L ++YLDLYL+HWP A++ + FP + G I + Y +TWKA+E LV +GLV+++G
Sbjct: 101 DLQLEYLDLYLMHWPYAFERGDNPFPKNADGTICYDSTHYKETWKALEALVAKGLVQALG 160
Query: 586 VSNFNSKQLERLLQHATVKPVVNQVECHPYLNQKRLKEFCEARGVKITXYSPLGSPDRPW 765
+SNFNS+Q++ +L A+V+P V QVECHPYL Q L C+ARG+++T YSPLGS DR W
Sbjct: 161 LSNFNSRQIDDILSVASVRPAVLQVECHPYLAQNELIAHCQARGLEVTAYSPLGSSDRAW 220
Query: 766 GQARRP 783
P
Sbjct: 221 RDPDEP 226
Score = 93.5 bits (222), Expect = 9e-19
Identities = 44/94 (46%), Positives = 56/94 (59%), Gaps = 1/94 (1%)
Frame = +3
Query: 123 VXFXXGASXPVFGXGXWXSKPGXVXXAVKXAIDIGXRHIDCAYVYGNXXXVGXAITSKIK 302
V G P+ G G W S+PG V AVK A+ +G RHIDCA +YGN +G A+ +
Sbjct: 6 VLLHTGQKMPLIGLGTWKSEPGQVKAAVKYALSVGYRHIDCAAIYGNEPEIGEALKEDVG 65
Query: 303 EG-VVTRXXLFITSKLWNTFHRPDLVRGALQEXL 401
G V R LF+TSKLWNT H P+ V AL++ L
Sbjct: 66 PGKAVPREELFVTSKLWNTKHHPEDVEPALRKTL 99
Score = 38.7 bits (86), Expect = 0.028
Identities = 14/41 (34%), Positives = 28/41 (68%)
Frame = +2
Query: 773 PDDPQXMEDPKLKXIADRLGKTVAQVLIRYQIDXGXIVXPE 895
PD+P +E+P + +A++ G++ AQ+L+R+Q+ I P+
Sbjct: 223 PDEPVLLEEPVVLALAEKYGRSPAQILLRWQVQRKVICIPK 263
>U05861-1|AAA18115.1| 323|Homo sapiens hepatic dihydrodiol
dehydrogenase protein.
Length = 323
Score = 131 bits (317), Expect = 3e-30
Identities = 62/129 (48%), Positives = 83/129 (64%), Gaps = 3/129 (2%)
Frame = +1
Query: 406 NLNVQYLDLYLIHWPQAYKEDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIG 585
NL + Y+DLYLIH+P + K + P D++GKI F VD TW+A+E GL KSIG
Sbjct: 105 NLQLDYVDLYLIHFPVSVKPGEEVIPKDENGKILFDTVDLCATWEAVEKCKDAGLAKSIG 164
Query: 586 VSNFNSKQLERLLQHATV--KPVVNQVECHPYLNQKRLKEFCEARGVKITXYSPLGS-PD 756
VSNFN +QLE +L + KPV NQVECHPY NQ++L +FC+++ + + YS LGS +
Sbjct: 165 VSNFNRRQLEMILNKPGLKYKPVCNQVECHPYFNQRKLLDFCKSKDIVLVAYSALGSHRE 224
Query: 757 RPWGQARRP 783
PW P
Sbjct: 225 EPWVDPNSP 233
Score = 77.0 bits (181), Expect = 9e-14
Identities = 43/96 (44%), Positives = 51/96 (53%), Gaps = 3/96 (3%)
Frame = +3
Query: 123 VXFXXGASXPVFGXGXWXSKP---GXVXXAVKXAIDIGXRHIDCAYVYGNXXXVGXAITS 293
V G PV G G + A K AI+ G RHID A++Y N VG AI S
Sbjct: 8 VKLNDGHFMPVLGFGTYAPAEVPKSKALEATKLAIEAGFRHIDSAHLYNNEEQVGLAIRS 67
Query: 294 KIKEGVVTRXXLFITSKLWNTFHRPDLVRGALQEXL 401
KI +G V R +F TSKLW HRP+LVR AL+ L
Sbjct: 68 KIADGSVKREDIFYTSKLWCNSHRPELVRPALERSL 103
Score = 37.9 bits (84), Expect = 0.050
Identities = 16/47 (34%), Positives = 27/47 (57%)
Frame = +2
Query: 746 ARRTDPGAKPDDPQXMEDPKLKXIADRLGKTVAQVLIRYQIDXGXIV 886
+ R +P P+ P +EDP L +A + +T A + +RYQ+ G +V
Sbjct: 221 SHREEPWVDPNSPVLLEDPVLCALAKKHKRTPALIALRYQLQRGVVV 267
>U05684-1|AAA16227.1| 323|Homo sapiens dihydrodiol dehydrogenase
protein.
Length = 323
Score = 131 bits (317), Expect = 3e-30
Identities = 62/129 (48%), Positives = 83/129 (64%), Gaps = 3/129 (2%)
Frame = +1
Query: 406 NLNVQYLDLYLIHWPQAYKEDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIG 585
NL + Y+DLYLIH+P + K + P D++GKI F VD TW+A+E GL KSIG
Sbjct: 105 NLQLDYVDLYLIHFPVSVKPGEEVIPKDENGKILFDTVDLCATWEAVEKCKDAGLAKSIG 164
Query: 586 VSNFNSKQLERLLQHATV--KPVVNQVECHPYLNQKRLKEFCEARGVKITXYSPLGS-PD 756
VSNFN +QLE +L + KPV NQVECHPY NQ++L +FC+++ + + YS LGS +
Sbjct: 165 VSNFNRRQLEMILNKPGLKYKPVCNQVECHPYFNQRKLLDFCKSKDIVLVAYSALGSHRE 224
Query: 757 RPWGQARRP 783
PW P
Sbjct: 225 EPWVDPNSP 233
Score = 77.0 bits (181), Expect = 9e-14
Identities = 43/96 (44%), Positives = 51/96 (53%), Gaps = 3/96 (3%)
Frame = +3
Query: 123 VXFXXGASXPVFGXGXWXSKP---GXVXXAVKXAIDIGXRHIDCAYVYGNXXXVGXAITS 293
V G PV G G + A K AI+ G RHID A++Y N VG AI S
Sbjct: 8 VKLNDGHFMPVLGFGTYAPAEVPKSKALEATKLAIEAGFRHIDSAHLYNNEEQVGLAIRS 67
Query: 294 KIKEGVVTRXXLFITSKLWNTFHRPDLVRGALQEXL 401
KI +G V R +F TSKLW HRP+LVR AL+ L
Sbjct: 68 KIADGSVKREDIFYTSKLWCNSHRPELVRPALERSL 103
Score = 37.9 bits (84), Expect = 0.050
Identities = 16/47 (34%), Positives = 27/47 (57%)
Frame = +2
Query: 746 ARRTDPGAKPDDPQXMEDPKLKXIADRLGKTVAQVLIRYQIDXGXIV 886
+ R +P P+ P +EDP L +A + +T A + +RYQ+ G +V
Sbjct: 221 SHREEPWVDPNSPVLLEDPVLCALAKKHKRTPALIALRYQLQRGVVV 267
>M86609-1|AAB02880.1| 323|Homo sapiens dihydrodiol dehydrogenase
protein.
Length = 323
Score = 131 bits (317), Expect = 3e-30
Identities = 62/129 (48%), Positives = 83/129 (64%), Gaps = 3/129 (2%)
Frame = +1
Query: 406 NLNVQYLDLYLIHWPQAYKEDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIG 585
NL + Y+DLYLIH+P + K + P D++GKI F VD TW+A+E GL KSIG
Sbjct: 105 NLQLDYVDLYLIHFPVSVKPGEEVIPKDENGKILFDTVDLCATWEAVEKCKDAGLAKSIG 164
Query: 586 VSNFNSKQLERLLQHATV--KPVVNQVECHPYLNQKRLKEFCEARGVKITXYSPLGS-PD 756
VSNFN +QLE +L + KPV NQVECHPY NQ++L +FC+++ + + YS LGS +
Sbjct: 165 VSNFNRRQLEMILNKPGLKYKPVCNQVECHPYFNQRKLLDFCKSKDIVLVAYSALGSHRE 224
Query: 757 RPWGQARRP 783
PW P
Sbjct: 225 EPWVDPNSP 233
Score = 77.0 bits (181), Expect = 9e-14
Identities = 43/96 (44%), Positives = 51/96 (53%), Gaps = 3/96 (3%)
Frame = +3
Query: 123 VXFXXGASXPVFGXGXWXSKP---GXVXXAVKXAIDIGXRHIDCAYVYGNXXXVGXAITS 293
V G PV G G + A K AI+ G RHID A++Y N VG AI S
Sbjct: 8 VKLNDGHFMPVLGFGTYAPAEVPKSKALEATKLAIEAGFRHIDSAHLYNNEEQVGLAIRS 67
Query: 294 KIKEGVVTRXXLFITSKLWNTFHRPDLVRGALQEXL 401
KI +G V R +F TSKLW HRP+LVR AL+ L
Sbjct: 68 KIADGSVKREDIFYTSKLWCNSHRPELVRPALERSL 103
Score = 37.9 bits (84), Expect = 0.050
Identities = 16/47 (34%), Positives = 27/47 (57%)
Frame = +2
Query: 746 ARRTDPGAKPDDPQXMEDPKLKXIADRLGKTVAQVLIRYQIDXGXIV 886
+ R +P P+ P +EDP L +A + +T A + +RYQ+ G +V
Sbjct: 221 SHREEPWVDPNSPVLLEDPVLCALAKKHKRTPALIALRYQLQRGVVV 267
>D26124-1|BAA05121.1| 306|Homo sapiens dihydrodiol dehydrogenase
isoform DD1 protein.
Length = 306
Score = 131 bits (317), Expect = 3e-30
Identities = 62/129 (48%), Positives = 83/129 (64%), Gaps = 3/129 (2%)
Frame = +1
Query: 406 NLNVQYLDLYLIHWPQAYKEDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIG 585
NL + Y+DLYLIH+P + K + P D++GKI F VD TW+A+E GL KSIG
Sbjct: 88 NLQLDYVDLYLIHFPVSVKPGEEVIPKDENGKILFDTVDLCATWEAVEKCKDAGLAKSIG 147
Query: 586 VSNFNSKQLERLLQHATV--KPVVNQVECHPYLNQKRLKEFCEARGVKITXYSPLGS-PD 756
VSNFN +QLE +L + KPV NQVECHPY NQ++L +FC+++ + + YS LGS +
Sbjct: 148 VSNFNRRQLEMILNKPGLKYKPVCNQVECHPYFNQRKLLDFCKSKDIVLVAYSALGSHRE 207
Query: 757 RPWGQARRP 783
PW P
Sbjct: 208 EPWVDPNSP 216
Score = 75.8 bits (178), Expect = 2e-13
Identities = 37/67 (55%), Positives = 44/67 (65%)
Frame = +3
Query: 201 AVKXAIDIGXRHIDCAYVYGNXXXVGXAITSKIKEGVVTRXXLFITSKLWNTFHRPDLVR 380
A K AI+ G RHID A++Y N VG AI SKI +G V R +F TSKLW HRP+LVR
Sbjct: 20 ATKLAIEAGFRHIDSAHLYNNEEQVGLAIRSKIADGSVKREDIFYTSKLWCNSHRPELVR 79
Query: 381 GALQEXL 401
AL+ L
Sbjct: 80 PALERSL 86
Score = 37.9 bits (84), Expect = 0.050
Identities = 16/47 (34%), Positives = 27/47 (57%)
Frame = +2
Query: 746 ARRTDPGAKPDDPQXMEDPKLKXIADRLGKTVAQVLIRYQIDXGXIV 886
+ R +P P+ P +EDP L +A + +T A + +RYQ+ G +V
Sbjct: 204 SHREEPWVDPNSPVLLEDPVLCALAKKHKRTPALIALRYQLQRGVVV 250
>BT007197-1|AAP35861.1| 323|Homo sapiens aldo-keto reductase family
1, member C1 (dihydrodiol dehydrogenase 1; 20-alpha
protein.
Length = 323
Score = 131 bits (317), Expect = 3e-30
Identities = 62/129 (48%), Positives = 83/129 (64%), Gaps = 3/129 (2%)
Frame = +1
Query: 406 NLNVQYLDLYLIHWPQAYKEDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIG 585
NL + Y+DLYLIH+P + K + P D++GKI F VD TW+A+E GL KSIG
Sbjct: 105 NLQLDYVDLYLIHFPVSVKPGEEVIPKDENGKILFDTVDLCATWEAVEKCKDAGLAKSIG 164
Query: 586 VSNFNSKQLERLLQHATV--KPVVNQVECHPYLNQKRLKEFCEARGVKITXYSPLGS-PD 756
VSNFN +QLE +L + KPV NQVECHPY NQ++L +FC+++ + + YS LGS +
Sbjct: 165 VSNFNRRQLEMILNKPGLKYKPVCNQVECHPYFNQRKLLDFCKSKDIVLVAYSALGSHRE 224
Query: 757 RPWGQARRP 783
PW P
Sbjct: 225 EPWVDPNSP 233
Score = 77.0 bits (181), Expect = 9e-14
Identities = 43/96 (44%), Positives = 51/96 (53%), Gaps = 3/96 (3%)
Frame = +3
Query: 123 VXFXXGASXPVFGXGXWXSKP---GXVXXAVKXAIDIGXRHIDCAYVYGNXXXVGXAITS 293
V G PV G G + A K AI+ G RHID A++Y N VG AI S
Sbjct: 8 VKLNDGHFMPVLGFGTYAPAEVPKSKALEATKLAIEAGFRHIDSAHLYNNEEQVGLAIRS 67
Query: 294 KIKEGVVTRXXLFITSKLWNTFHRPDLVRGALQEXL 401
KI +G V R +F TSKLW HRP+LVR AL+ L
Sbjct: 68 KIADGSVKREDIFYTSKLWCNSHRPELVRPALERSL 103
Score = 37.9 bits (84), Expect = 0.050
Identities = 16/47 (34%), Positives = 27/47 (57%)
Frame = +2
Query: 746 ARRTDPGAKPDDPQXMEDPKLKXIADRLGKTVAQVLIRYQIDXGXIV 886
+ R +P P+ P +EDP L +A + +T A + +RYQ+ G +V
Sbjct: 221 SHREEPWVDPNSPVLLEDPVLCALAKKHKRTPALIALRYQLQRGVVV 267
>BC040210-1|AAH40210.1| 323|Homo sapiens aldo-keto reductase family
1, member C1 (dihydrodiol dehydrogenase 1; 20-alpha
protein.
Length = 323
Score = 131 bits (317), Expect = 3e-30
Identities = 62/129 (48%), Positives = 83/129 (64%), Gaps = 3/129 (2%)
Frame = +1
Query: 406 NLNVQYLDLYLIHWPQAYKEDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIG 585
NL + Y+DLYLIH+P + K + P D++GKI F VD TW+A+E GL KSIG
Sbjct: 105 NLQLDYVDLYLIHFPVSVKPGEEVIPKDENGKILFDTVDLCATWEAVEKCKDAGLAKSIG 164
Query: 586 VSNFNSKQLERLLQHATV--KPVVNQVECHPYLNQKRLKEFCEARGVKITXYSPLGS-PD 756
VSNFN +QLE +L + KPV NQVECHPY NQ++L +FC+++ + + YS LGS +
Sbjct: 165 VSNFNRRQLEMILNKPGLKYKPVCNQVECHPYFNQRKLLDFCKSKDIVLVAYSALGSHRE 224
Query: 757 RPWGQARRP 783
PW P
Sbjct: 225 EPWVDPNSP 233
Score = 77.0 bits (181), Expect = 9e-14
Identities = 43/96 (44%), Positives = 51/96 (53%), Gaps = 3/96 (3%)
Frame = +3
Query: 123 VXFXXGASXPVFGXGXWXSKP---GXVXXAVKXAIDIGXRHIDCAYVYGNXXXVGXAITS 293
V G PV G G + A K AI+ G RHID A++Y N VG AI S
Sbjct: 8 VKLNDGHFMPVLGFGTYAPAEVPKSKALEATKLAIEAGFRHIDSAHLYNNEEQVGLAIRS 67
Query: 294 KIKEGVVTRXXLFITSKLWNTFHRPDLVRGALQEXL 401
KI +G V R +F TSKLW HRP+LVR AL+ L
Sbjct: 68 KIADGSVKREDIFYTSKLWCNSHRPELVRPALERSL 103
Score = 37.9 bits (84), Expect = 0.050
Identities = 16/47 (34%), Positives = 27/47 (57%)
Frame = +2
Query: 746 ARRTDPGAKPDDPQXMEDPKLKXIADRLGKTVAQVLIRYQIDXGXIV 886
+ R +P P+ P +EDP L +A + +T A + +RYQ+ G +V
Sbjct: 221 SHREEPWVDPNSPVLLEDPVLCALAKKHKRTPALIALRYQLQRGVVV 267
>BC020216-1|AAH20216.1| 323|Homo sapiens aldo-keto reductase family
1, member C1 (dihydrodiol dehydrogenase 1; 20-alpha
protein.
Length = 323
Score = 131 bits (317), Expect = 3e-30
Identities = 62/129 (48%), Positives = 83/129 (64%), Gaps = 3/129 (2%)
Frame = +1
Query: 406 NLNVQYLDLYLIHWPQAYKEDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIG 585
NL + Y+DLYLIH+P + K + P D++GKI F VD TW+A+E GL KSIG
Sbjct: 105 NLQLDYVDLYLIHFPVSVKPGEEVIPKDENGKILFDTVDLCATWEAVEKCKDAGLAKSIG 164
Query: 586 VSNFNSKQLERLLQHATV--KPVVNQVECHPYLNQKRLKEFCEARGVKITXYSPLGS-PD 756
VSNFN +QLE +L + KPV NQVECHPY NQ++L +FC+++ + + YS LGS +
Sbjct: 165 VSNFNRRQLEMILNKPGLKYKPVCNQVECHPYFNQRKLLDFCKSKDIVLVAYSALGSHRE 224
Query: 757 RPWGQARRP 783
PW P
Sbjct: 225 EPWVDPNSP 233
Score = 77.0 bits (181), Expect = 9e-14
Identities = 43/96 (44%), Positives = 51/96 (53%), Gaps = 3/96 (3%)
Frame = +3
Query: 123 VXFXXGASXPVFGXGXWXSKP---GXVXXAVKXAIDIGXRHIDCAYVYGNXXXVGXAITS 293
V G PV G G + A K AI+ G RHID A++Y N VG AI S
Sbjct: 8 VKLNDGHFMPVLGFGTYAPAEVPKSKALEATKLAIEAGFRHIDSAHLYNNEEQVGLAIRS 67
Query: 294 KIKEGVVTRXXLFITSKLWNTFHRPDLVRGALQEXL 401
KI +G V R +F TSKLW HRP+LVR AL+ L
Sbjct: 68 KIADGSVKREDIFYTSKLWCNSHRPELVRPALERSL 103
Score = 37.9 bits (84), Expect = 0.050
Identities = 16/47 (34%), Positives = 27/47 (57%)
Frame = +2
Query: 746 ARRTDPGAKPDDPQXMEDPKLKXIADRLGKTVAQVLIRYQIDXGXIV 886
+ R +P P+ P +EDP L +A + +T A + +RYQ+ G +V
Sbjct: 221 SHREEPWVDPNSPVLLEDPVLCALAKKHKRTPALIALRYQLQRGVVV 267
>BC015490-1|AAH15490.1| 323|Homo sapiens aldo-keto reductase family
1, member C1 (dihydrodiol dehydrogenase 1; 20-alpha
protein.
Length = 323
Score = 131 bits (317), Expect = 3e-30
Identities = 62/129 (48%), Positives = 83/129 (64%), Gaps = 3/129 (2%)
Frame = +1
Query: 406 NLNVQYLDLYLIHWPQAYKEDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIG 585
NL + Y+DLYLIH+P + K + P D++GKI F VD TW+A+E GL KSIG
Sbjct: 105 NLQLDYVDLYLIHFPVSVKPGEEVIPKDENGKILFDTVDLCATWEAVEKCKDAGLAKSIG 164
Query: 586 VSNFNSKQLERLLQHATV--KPVVNQVECHPYLNQKRLKEFCEARGVKITXYSPLGS-PD 756
VSNFN +QLE +L + KPV NQVECHPY NQ++L +FC+++ + + YS LGS +
Sbjct: 165 VSNFNRRQLEMILNKPGLKYKPVCNQVECHPYFNQRKLLDFCKSKDIVLVAYSALGSHRE 224
Query: 757 RPWGQARRP 783
PW P
Sbjct: 225 EPWVDPNSP 233
Score = 77.0 bits (181), Expect = 9e-14
Identities = 43/96 (44%), Positives = 51/96 (53%), Gaps = 3/96 (3%)
Frame = +3
Query: 123 VXFXXGASXPVFGXGXWXSKP---GXVXXAVKXAIDIGXRHIDCAYVYGNXXXVGXAITS 293
V G PV G G + A K AI+ G RHID A++Y N VG AI S
Sbjct: 8 VKLNDGHFMPVLGFGTYAPAEVPKSKALEATKLAIEAGFRHIDSAHLYNNEEQVGLAIRS 67
Query: 294 KIKEGVVTRXXLFITSKLWNTFHRPDLVRGALQEXL 401
KI +G V R +F TSKLW HRP+LVR AL+ L
Sbjct: 68 KIADGSVKREDIFYTSKLWCNSHRPELVRPALERSL 103
Score = 37.9 bits (84), Expect = 0.050
Identities = 16/47 (34%), Positives = 27/47 (57%)
Frame = +2
Query: 746 ARRTDPGAKPDDPQXMEDPKLKXIADRLGKTVAQVLIRYQIDXGXIV 886
+ R +P P+ P +EDP L +A + +T A + +RYQ+ G +V
Sbjct: 221 SHREEPWVDPNSPVLLEDPVLCALAKKHKRTPALIALRYQLQRGVVV 267
>AL713867-3|CAI16410.1| 247|Homo sapiens aldo-keto reductase family
1, member C1 (dihydrodiol dehydrogenase 1; 20-alpha
protein.
Length = 247
Score = 131 bits (317), Expect = 3e-30
Identities = 62/129 (48%), Positives = 83/129 (64%), Gaps = 3/129 (2%)
Frame = +1
Query: 406 NLNVQYLDLYLIHWPQAYKEDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIG 585
NL + Y+DLYLIH+P + K + P D++GKI F VD TW+A+E GL KSIG
Sbjct: 71 NLQLDYVDLYLIHFPVSVKPGEEVIPKDENGKILFDTVDLCATWEAVEKCKDAGLAKSIG 130
Query: 586 VSNFNSKQLERLLQHATV--KPVVNQVECHPYLNQKRLKEFCEARGVKITXYSPLGS-PD 756
VSNFN +QLE +L + KPV NQVECHPY NQ++L +FC+++ + + YS LGS +
Sbjct: 131 VSNFNRRQLEMILNKPGLKYKPVCNQVECHPYFNQRKLLDFCKSKDIVLVAYSALGSHRE 190
Query: 757 RPWGQARRP 783
PW P
Sbjct: 191 EPWVDPNSP 199
Score = 51.2 bits (117), Expect = 5e-06
Identities = 25/43 (58%), Positives = 29/43 (67%)
Frame = +3
Query: 273 VGXAITSKIKEGVVTRXXLFITSKLWNTFHRPDLVRGALQEXL 401
VG AI SKI +G V R +F TSKLW HRP+LVR AL+ L
Sbjct: 27 VGLAIRSKIADGSVKREDIFYTSKLWCNSHRPELVRPALERSL 69
Score = 37.9 bits (84), Expect = 0.050
Identities = 16/47 (34%), Positives = 27/47 (57%)
Frame = +2
Query: 746 ARRTDPGAKPDDPQXMEDPKLKXIADRLGKTVAQVLIRYQIDXGXIV 886
+ R +P P+ P +EDP L +A + +T A + +RYQ+ G +V
Sbjct: 187 SHREEPWVDPNSPVLLEDPVLCALAKKHKRTPALIALRYQLQRGVVV 233
>AL713867-2|CAI16409.1| 323|Homo sapiens aldo-keto reductase family
1, member C1 (dihydrodiol dehydrogenase 1; 20-alpha
protein.
Length = 323
Score = 131 bits (317), Expect = 3e-30
Identities = 62/129 (48%), Positives = 83/129 (64%), Gaps = 3/129 (2%)
Frame = +1
Query: 406 NLNVQYLDLYLIHWPQAYKEDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIG 585
NL + Y+DLYLIH+P + K + P D++GKI F VD TW+A+E GL KSIG
Sbjct: 105 NLQLDYVDLYLIHFPVSVKPGEEVIPKDENGKILFDTVDLCATWEAVEKCKDAGLAKSIG 164
Query: 586 VSNFNSKQLERLLQHATV--KPVVNQVECHPYLNQKRLKEFCEARGVKITXYSPLGS-PD 756
VSNFN +QLE +L + KPV NQVECHPY NQ++L +FC+++ + + YS LGS +
Sbjct: 165 VSNFNRRQLEMILNKPGLKYKPVCNQVECHPYFNQRKLLDFCKSKDIVLVAYSALGSHRE 224
Query: 757 RPWGQARRP 783
PW P
Sbjct: 225 EPWVDPNSP 233
Score = 77.0 bits (181), Expect = 9e-14
Identities = 43/96 (44%), Positives = 51/96 (53%), Gaps = 3/96 (3%)
Frame = +3
Query: 123 VXFXXGASXPVFGXGXWXSKP---GXVXXAVKXAIDIGXRHIDCAYVYGNXXXVGXAITS 293
V G PV G G + A K AI+ G RHID A++Y N VG AI S
Sbjct: 8 VKLNDGHFMPVLGFGTYAPAEVPKSKALEATKLAIEAGFRHIDSAHLYNNEEQVGLAIRS 67
Query: 294 KIKEGVVTRXXLFITSKLWNTFHRPDLVRGALQEXL 401
KI +G V R +F TSKLW HRP+LVR AL+ L
Sbjct: 68 KIADGSVKREDIFYTSKLWCNSHRPELVRPALERSL 103
Score = 37.9 bits (84), Expect = 0.050
Identities = 16/47 (34%), Positives = 27/47 (57%)
Frame = +2
Query: 746 ARRTDPGAKPDDPQXMEDPKLKXIADRLGKTVAQVLIRYQIDXGXIV 886
+ R +P P+ P +EDP L +A + +T A + +RYQ+ G +V
Sbjct: 221 SHREEPWVDPNSPVLLEDPVLCALAKKHKRTPALIALRYQLQRGVVV 267
>AB032150-1|BAA92886.1| 323|Homo sapiens 20 alph-hydroxysteroid
dehydrogenase protein.
Length = 323
Score = 131 bits (317), Expect = 3e-30
Identities = 62/129 (48%), Positives = 83/129 (64%), Gaps = 3/129 (2%)
Frame = +1
Query: 406 NLNVQYLDLYLIHWPQAYKEDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIG 585
NL + Y+DLYLIH+P + K + P D++GKI F VD TW+A+E GL KSIG
Sbjct: 105 NLQLDYVDLYLIHFPVSVKPGEEVIPKDENGKILFDTVDLCATWEAVEKCKDAGLAKSIG 164
Query: 586 VSNFNSKQLERLLQHATV--KPVVNQVECHPYLNQKRLKEFCEARGVKITXYSPLGS-PD 756
VSNFN +QLE +L + KPV NQVECHPY NQ++L +FC+++ + + YS LGS +
Sbjct: 165 VSNFNRRQLEMILNKPGLKYKPVCNQVECHPYFNQRKLLDFCKSKDIVLVAYSALGSHRE 224
Query: 757 RPWGQARRP 783
PW P
Sbjct: 225 EPWVDPNSP 233
Score = 77.0 bits (181), Expect = 9e-14
Identities = 43/96 (44%), Positives = 51/96 (53%), Gaps = 3/96 (3%)
Frame = +3
Query: 123 VXFXXGASXPVFGXGXWXSKP---GXVXXAVKXAIDIGXRHIDCAYVYGNXXXVGXAITS 293
V G PV G G + A K AI+ G RHID A++Y N VG AI S
Sbjct: 8 VKLNDGHFMPVLGFGTYAPAEVPKSKALEATKLAIEAGFRHIDSAHLYNNEEQVGLAIRS 67
Query: 294 KIKEGVVTRXXLFITSKLWNTFHRPDLVRGALQEXL 401
KI +G V R +F TSKLW HRP+LVR AL+ L
Sbjct: 68 KIADGSVKREDIFYTSKLWCNSHRPELVRPALERSL 103
Score = 37.9 bits (84), Expect = 0.050
Identities = 16/47 (34%), Positives = 27/47 (57%)
Frame = +2
Query: 746 ARRTDPGAKPDDPQXMEDPKLKXIADRLGKTVAQVLIRYQIDXGXIV 886
+ R +P P+ P +EDP L +A + +T A + +RYQ+ G +V
Sbjct: 221 SHREEPWVDPNSPVLLEDPVLCALAKKHKRTPALIALRYQLQRGVVV 267
>AB031083-1|BAA92883.1| 323|Homo sapiens 20 alpha-hydroxysteroid
dehydrogenase protein.
Length = 323
Score = 131 bits (317), Expect = 3e-30
Identities = 62/129 (48%), Positives = 83/129 (64%), Gaps = 3/129 (2%)
Frame = +1
Query: 406 NLNVQYLDLYLIHWPQAYKEDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIG 585
NL + Y+DLYLIH+P + K + P D++GKI F VD TW+A+E GL KSIG
Sbjct: 105 NLQLDYVDLYLIHFPVSVKPGEEVIPKDENGKILFDTVDLCATWEAVEKCKDAGLAKSIG 164
Query: 586 VSNFNSKQLERLLQHATV--KPVVNQVECHPYLNQKRLKEFCEARGVKITXYSPLGS-PD 756
VSNFN +QLE +L + KPV NQVECHPY NQ++L +FC+++ + + YS LGS +
Sbjct: 165 VSNFNRRQLEMILNKPGLKYKPVCNQVECHPYFNQRKLLDFCKSKDIVLVAYSALGSHRE 224
Query: 757 RPWGQARRP 783
PW P
Sbjct: 225 EPWVDPNSP 233
Score = 77.0 bits (181), Expect = 9e-14
Identities = 43/96 (44%), Positives = 51/96 (53%), Gaps = 3/96 (3%)
Frame = +3
Query: 123 VXFXXGASXPVFGXGXWXSKP---GXVXXAVKXAIDIGXRHIDCAYVYGNXXXVGXAITS 293
V G PV G G + A K AI+ G RHID A++Y N VG AI S
Sbjct: 8 VKLNDGHFMPVLGFGTYAPAEVPKSKALEATKLAIEAGFRHIDSAHLYNNEEQVGLAIRS 67
Query: 294 KIKEGVVTRXXLFITSKLWNTFHRPDLVRGALQEXL 401
KI +G V R +F TSKLW HRP+LVR AL+ L
Sbjct: 68 KIADGSVKREDIFYTSKLWCNSHRPELVRPALERSL 103
Score = 37.9 bits (84), Expect = 0.050
Identities = 16/47 (34%), Positives = 27/47 (57%)
Frame = +2
Query: 746 ARRTDPGAKPDDPQXMEDPKLKXIADRLGKTVAQVLIRYQIDXGXIV 886
+ R +P P+ P +EDP L +A + +T A + +RYQ+ G +V
Sbjct: 221 SHREEPWVDPNSPVLLEDPVLCALAKKHKRTPALIALRYQLQRGVVV 267
>S68330-1|AAD14013.1| 323|Homo sapiens chlordecone reductase
homolog protein.
Length = 323
Score = 130 bits (315), Expect = 5e-30
Identities = 62/129 (48%), Positives = 82/129 (63%), Gaps = 3/129 (2%)
Frame = +1
Query: 406 NLNVQYLDLYLIHWPQAYKEDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIG 585
NL + Y+DLYLIH+P + K + P D++GKI F VD TW+AME GL KSIG
Sbjct: 105 NLQLDYVDLYLIHFPVSVKPGEEVIPKDENGKILFDTVDLCATWEAMEKCKDAGLAKSIG 164
Query: 586 VSNFNSKQLERLLQHATVK--PVVNQVECHPYLNQKRLKEFCEARGVKITXYSPLGS-PD 756
VSNFN + LE +L +K PV NQVECHPY NQ++L +FC+++ + + YS LGS +
Sbjct: 165 VSNFNHRLLEMILNEPGLKYEPVCNQVECHPYFNQRKLLDFCKSKDIVLVAYSALGSHRE 224
Query: 757 RPWGQARRP 783
PW P
Sbjct: 225 EPWVDPNSP 233
Score = 79.4 bits (187), Expect = 2e-14
Identities = 44/96 (45%), Positives = 52/96 (54%), Gaps = 3/96 (3%)
Frame = +3
Query: 123 VXFXXGASXPVFGXGXWXSKP---GXVXXAVKXAIDIGXRHIDCAYVYGNXXXVGXAITS 293
V G PV G G + AVK AI+ G HID A+VY N VG AI S
Sbjct: 8 VKLNDGHFMPVLGFGTYAPAEVPKSKALEAVKLAIEAGFHHIDSAHVYNNEEQVGLAIRS 67
Query: 294 KIKEGVVTRXXLFITSKLWNTFHRPDLVRGALQEXL 401
KI +G V R +F TSKLW+ HRP+LVR AL+ L
Sbjct: 68 KIADGSVKREDIFYTSKLWSNSHRPELVRPALERSL 103
Score = 37.9 bits (84), Expect = 0.050
Identities = 16/47 (34%), Positives = 27/47 (57%)
Frame = +2
Query: 746 ARRTDPGAKPDDPQXMEDPKLKXIADRLGKTVAQVLIRYQIDXGXIV 886
+ R +P P+ P +EDP L +A + +T A + +RYQ+ G +V
Sbjct: 221 SHREEPWVDPNSPVLLEDPVLCALAKKHKRTPALIALRYQLQRGVVV 267
>U05598-1|AAA20937.1| 323|Homo sapiens dihydrodiol dehydrogenase
protein.
Length = 323
Score = 130 bits (314), Expect = 7e-30
Identities = 62/129 (48%), Positives = 82/129 (63%), Gaps = 3/129 (2%)
Frame = +1
Query: 406 NLNVQYLDLYLIHWPQAYKEDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIG 585
NL + Y+DLYLIH+P + K + P D++GKI F VD TW+AME GL KSIG
Sbjct: 105 NLQLDYVDLYLIHFPVSVKPGEEVIPKDENGKILFDTVDLCATWEAMEKCKDAGLAKSIG 164
Query: 586 VSNFNSKQLERLLQHATV--KPVVNQVECHPYLNQKRLKEFCEARGVKITXYSPLGS-PD 756
VSNFN + LE +L + KPV NQVECHPY NQ++L +FC+++ + + YS LGS +
Sbjct: 165 VSNFNHRLLEMILNKPGLKYKPVCNQVECHPYFNQRKLLDFCKSKDIVLVAYSALGSHRE 224
Query: 757 RPWGQARRP 783
PW P
Sbjct: 225 EPWVDPNSP 233
Score = 79.4 bits (187), Expect = 2e-14
Identities = 44/96 (45%), Positives = 52/96 (54%), Gaps = 3/96 (3%)
Frame = +3
Query: 123 VXFXXGASXPVFGXGXWXSKP---GXVXXAVKXAIDIGXRHIDCAYVYGNXXXVGXAITS 293
V G PV G G + AVK AI+ G HID A+VY N VG AI S
Sbjct: 8 VKLNDGHFMPVLGFGTYAPAEVPKSKALEAVKLAIEAGFHHIDSAHVYNNEEQVGLAIRS 67
Query: 294 KIKEGVVTRXXLFITSKLWNTFHRPDLVRGALQEXL 401
KI +G V R +F TSKLW+ HRP+LVR AL+ L
Sbjct: 68 KIADGSVKREDIFYTSKLWSNSHRPELVRPALERSL 103
Score = 37.9 bits (84), Expect = 0.050
Identities = 16/47 (34%), Positives = 27/47 (57%)
Frame = +2
Query: 746 ARRTDPGAKPDDPQXMEDPKLKXIADRLGKTVAQVLIRYQIDXGXIV 886
+ R +P P+ P +EDP L +A + +T A + +RYQ+ G +V
Sbjct: 221 SHREEPWVDPNSPVLLEDPVLCALAKKHKRTPALIALRYQLQRGVVV 267
>BT006653-1|AAP35299.1| 323|Homo sapiens aldo-keto reductase family
1, member C2 (dihydrodiol dehydrogenase 2; bile acid
protein.
Length = 323
Score = 130 bits (314), Expect = 7e-30
Identities = 62/129 (48%), Positives = 82/129 (63%), Gaps = 3/129 (2%)
Frame = +1
Query: 406 NLNVQYLDLYLIHWPQAYKEDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIG 585
NL + Y+DLYLIH+P + K + P D++GKI F VD TW+AME GL KSIG
Sbjct: 105 NLQLDYVDLYLIHFPVSVKPGEEVIPKDENGKILFDTVDLCATWEAMEKCKDAGLAKSIG 164
Query: 586 VSNFNSKQLERLLQHATV--KPVVNQVECHPYLNQKRLKEFCEARGVKITXYSPLGS-PD 756
VSNFN + LE +L + KPV NQVECHPY NQ++L +FC+++ + + YS LGS +
Sbjct: 165 VSNFNHRLLEMILNKPGLKYKPVCNQVECHPYFNQRKLLDFCKSKDIVLVAYSALGSHRE 224
Query: 757 RPWGQARRP 783
PW P
Sbjct: 225 EPWVDPNSP 233
Score = 79.4 bits (187), Expect = 2e-14
Identities = 44/96 (45%), Positives = 52/96 (54%), Gaps = 3/96 (3%)
Frame = +3
Query: 123 VXFXXGASXPVFGXGXWXSKP---GXVXXAVKXAIDIGXRHIDCAYVYGNXXXVGXAITS 293
V G PV G G + AVK AI+ G HID A+VY N VG AI S
Sbjct: 8 VKLNDGHFMPVLGFGTYAPAEVPKSKALEAVKLAIEAGFHHIDSAHVYNNEEQVGLAIRS 67
Query: 294 KIKEGVVTRXXLFITSKLWNTFHRPDLVRGALQEXL 401
KI +G V R +F TSKLW+ HRP+LVR AL+ L
Sbjct: 68 KIADGSVKREDIFYTSKLWSNSHRPELVRPALERSL 103
Score = 37.9 bits (84), Expect = 0.050
Identities = 16/47 (34%), Positives = 27/47 (57%)
Frame = +2
Query: 746 ARRTDPGAKPDDPQXMEDPKLKXIADRLGKTVAQVLIRYQIDXGXIV 886
+ R +P P+ P +EDP L +A + +T A + +RYQ+ G +V
Sbjct: 221 SHREEPWVDPNSPVLLEDPVLCALAKKHKRTPALIALRYQLQRGVVV 267
>BC063574-1|AAH63574.1| 323|Homo sapiens aldo-keto reductase family
1, member C2 (dihydrodiol dehydrogenase 2; bile acid
protein.
Length = 323
Score = 130 bits (314), Expect = 7e-30
Identities = 62/129 (48%), Positives = 82/129 (63%), Gaps = 3/129 (2%)
Frame = +1
Query: 406 NLNVQYLDLYLIHWPQAYKEDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIG 585
NL + Y+DLYLIH+P + K + P D++GKI F VD TW+AME GL KSIG
Sbjct: 105 NLQLDYVDLYLIHFPVSVKPGEEVIPKDENGKILFDTVDLCATWEAMEKCKDAGLAKSIG 164
Query: 586 VSNFNSKQLERLLQHATV--KPVVNQVECHPYLNQKRLKEFCEARGVKITXYSPLGS-PD 756
VSNFN + LE +L + KPV NQVECHPY NQ++L +FC+++ + + YS LGS +
Sbjct: 165 VSNFNHRLLEMILNKPGLKYKPVCNQVECHPYFNQRKLLDFCKSKDIVLVAYSALGSHRE 224
Query: 757 RPWGQARRP 783
PW P
Sbjct: 225 EPWVDPNSP 233
Score = 79.4 bits (187), Expect = 2e-14
Identities = 44/96 (45%), Positives = 52/96 (54%), Gaps = 3/96 (3%)
Frame = +3
Query: 123 VXFXXGASXPVFGXGXWXSKP---GXVXXAVKXAIDIGXRHIDCAYVYGNXXXVGXAITS 293
V G PV G G + AVK AI+ G HID A+VY N VG AI S
Sbjct: 8 VKLNDGHFMPVLGFGTYAPAEVPKSKALEAVKLAIEAGFHHIDSAHVYNNEEQVGLAIRS 67
Query: 294 KIKEGVVTRXXLFITSKLWNTFHRPDLVRGALQEXL 401
KI +G V R +F TSKLW+ HRP+LVR AL+ L
Sbjct: 68 KIADGSVKREDIFYTSKLWSNSHRPELVRPALERSL 103
Score = 37.9 bits (84), Expect = 0.050
Identities = 16/47 (34%), Positives = 27/47 (57%)
Frame = +2
Query: 746 ARRTDPGAKPDDPQXMEDPKLKXIADRLGKTVAQVLIRYQIDXGXIV 886
+ R +P P+ P +EDP L +A + +T A + +RYQ+ G +V
Sbjct: 221 SHREEPWVDPNSPVLLEDPVLCALAKKHKRTPALIALRYQLQRGVVV 267
>BC007024-1|AAH07024.1| 323|Homo sapiens aldo-keto reductase family
1, member C2 (dihydrodiol dehydrogenase 2; bile acid
protein.
Length = 323
Score = 130 bits (314), Expect = 7e-30
Identities = 62/129 (48%), Positives = 82/129 (63%), Gaps = 3/129 (2%)
Frame = +1
Query: 406 NLNVQYLDLYLIHWPQAYKEDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIG 585
NL + Y+DLYLIH+P + K + P D++GKI F VD TW+AME GL KSIG
Sbjct: 105 NLQLDYVDLYLIHFPVSVKPGEEVIPKDENGKILFDTVDLCATWEAMEKCKDAGLAKSIG 164
Query: 586 VSNFNSKQLERLLQHATV--KPVVNQVECHPYLNQKRLKEFCEARGVKITXYSPLGS-PD 756
VSNFN + LE +L + KPV NQVECHPY NQ++L +FC+++ + + YS LGS +
Sbjct: 165 VSNFNHRLLEMILNKPGLKYKPVCNQVECHPYFNQRKLLDFCKSKDIVLVAYSALGSHRE 224
Query: 757 RPWGQARRP 783
PW P
Sbjct: 225 EPWVDPNSP 233
Score = 79.4 bits (187), Expect = 2e-14
Identities = 44/96 (45%), Positives = 52/96 (54%), Gaps = 3/96 (3%)
Frame = +3
Query: 123 VXFXXGASXPVFGXGXWXSKP---GXVXXAVKXAIDIGXRHIDCAYVYGNXXXVGXAITS 293
V G PV G G + AVK AI+ G HID A+VY N VG AI S
Sbjct: 8 VKLNDGHFMPVLGFGTYAPAEVPKSKALEAVKLAIEAGFHHIDSAHVYNNEEQVGLAIRS 67
Query: 294 KIKEGVVTRXXLFITSKLWNTFHRPDLVRGALQEXL 401
KI +G V R +F TSKLW+ HRP+LVR AL+ L
Sbjct: 68 KIADGSVKREDIFYTSKLWSNSHRPELVRPALERSL 103
Score = 37.9 bits (84), Expect = 0.050
Identities = 16/47 (34%), Positives = 27/47 (57%)
Frame = +2
Query: 746 ARRTDPGAKPDDPQXMEDPKLKXIADRLGKTVAQVLIRYQIDXGXIV 886
+ R +P P+ P +EDP L +A + +T A + +RYQ+ G +V
Sbjct: 221 SHREEPWVDPNSPVLLEDPVLCALAKKHKRTPALIALRYQLQRGVVV 267
>AL713867-1|CAI16408.1| 323|Homo sapiens aldo-keto reductase family
1, member C2 (dihydrodiol dehydrogenase 2; bile acid
protein.
Length = 323
Score = 130 bits (314), Expect = 7e-30
Identities = 62/129 (48%), Positives = 82/129 (63%), Gaps = 3/129 (2%)
Frame = +1
Query: 406 NLNVQYLDLYLIHWPQAYKEDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIG 585
NL + Y+DLYLIH+P + K + P D++GKI F VD TW+AME GL KSIG
Sbjct: 105 NLQLDYVDLYLIHFPVSVKPGEEVIPKDENGKILFDTVDLCATWEAMEKCKDAGLAKSIG 164
Query: 586 VSNFNSKQLERLLQHATV--KPVVNQVECHPYLNQKRLKEFCEARGVKITXYSPLGS-PD 756
VSNFN + LE +L + KPV NQVECHPY NQ++L +FC+++ + + YS LGS +
Sbjct: 165 VSNFNHRLLEMILNKPGLKYKPVCNQVECHPYFNQRKLLDFCKSKDIVLVAYSALGSHRE 224
Query: 757 RPWGQARRP 783
PW P
Sbjct: 225 EPWVDPNSP 233
Score = 79.4 bits (187), Expect = 2e-14
Identities = 44/96 (45%), Positives = 52/96 (54%), Gaps = 3/96 (3%)
Frame = +3
Query: 123 VXFXXGASXPVFGXGXWXSKP---GXVXXAVKXAIDIGXRHIDCAYVYGNXXXVGXAITS 293
V G PV G G + AVK AI+ G HID A+VY N VG AI S
Sbjct: 8 VKLNDGHFMPVLGFGTYAPAEVPKSKALEAVKLAIEAGFHHIDSAHVYNNEEQVGLAIRS 67
Query: 294 KIKEGVVTRXXLFITSKLWNTFHRPDLVRGALQEXL 401
KI +G V R +F TSKLW+ HRP+LVR AL+ L
Sbjct: 68 KIADGSVKREDIFYTSKLWSNSHRPELVRPALERSL 103
Score = 37.9 bits (84), Expect = 0.050
Identities = 16/47 (34%), Positives = 27/47 (57%)
Frame = +2
Query: 746 ARRTDPGAKPDDPQXMEDPKLKXIADRLGKTVAQVLIRYQIDXGXIV 886
+ R +P P+ P +EDP L +A + +T A + +RYQ+ G +V
Sbjct: 221 SHREEPWVDPNSPVLLEDPVLCALAKKHKRTPALIALRYQLQRGVVV 267
>AL391427-1|CAI14726.1| 323|Homo sapiens aldo-keto reductase family
1, member C2 (dihydrodiol dehydrogenase 2; bile acid
protein.
Length = 323
Score = 130 bits (314), Expect = 7e-30
Identities = 62/129 (48%), Positives = 82/129 (63%), Gaps = 3/129 (2%)
Frame = +1
Query: 406 NLNVQYLDLYLIHWPQAYKEDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIG 585
NL + Y+DLYLIH+P + K + P D++GKI F VD TW+AME GL KSIG
Sbjct: 105 NLQLDYVDLYLIHFPVSVKPGEEVIPKDENGKILFDTVDLCATWEAMEKCKDAGLAKSIG 164
Query: 586 VSNFNSKQLERLLQHATV--KPVVNQVECHPYLNQKRLKEFCEARGVKITXYSPLGS-PD 756
VSNFN + LE +L + KPV NQVECHPY NQ++L +FC+++ + + YS LGS +
Sbjct: 165 VSNFNHRLLEMILNKPGLKYKPVCNQVECHPYFNQRKLLDFCKSKDIVLVAYSALGSHRE 224
Query: 757 RPWGQARRP 783
PW P
Sbjct: 225 EPWVDPNSP 233
Score = 79.4 bits (187), Expect = 2e-14
Identities = 44/96 (45%), Positives = 52/96 (54%), Gaps = 3/96 (3%)
Frame = +3
Query: 123 VXFXXGASXPVFGXGXWXSKP---GXVXXAVKXAIDIGXRHIDCAYVYGNXXXVGXAITS 293
V G PV G G + AVK AI+ G HID A+VY N VG AI S
Sbjct: 8 VKLNDGHFMPVLGFGTYAPAEVPKSKALEAVKLAIEAGFHHIDSAHVYNNEEQVGLAIRS 67
Query: 294 KIKEGVVTRXXLFITSKLWNTFHRPDLVRGALQEXL 401
KI +G V R +F TSKLW+ HRP+LVR AL+ L
Sbjct: 68 KIADGSVKREDIFYTSKLWSNSHRPELVRPALERSL 103
Score = 37.9 bits (84), Expect = 0.050
Identities = 16/47 (34%), Positives = 27/47 (57%)
Frame = +2
Query: 746 ARRTDPGAKPDDPQXMEDPKLKXIADRLGKTVAQVLIRYQIDXGXIV 886
+ R +P P+ P +EDP L +A + +T A + +RYQ+ G +V
Sbjct: 221 SHREEPWVDPNSPVLLEDPVLCALAKKHKRTPALIALRYQLQRGVVV 267
>AB209017-1|BAD92254.1| 286|Homo sapiens aldo-keto reductase family
1, member C2 variant protein.
Length = 286
Score = 130 bits (314), Expect = 7e-30
Identities = 62/129 (48%), Positives = 82/129 (63%), Gaps = 3/129 (2%)
Frame = +1
Query: 406 NLNVQYLDLYLIHWPQAYKEDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIG 585
NL + Y+DLYLIH+P + K + P D++GKI F VD TW+AME GL KSIG
Sbjct: 118 NLQLDYVDLYLIHFPVSVKPGEEVIPKDENGKILFDTVDLCATWEAMEKCKDAGLAKSIG 177
Query: 586 VSNFNSKQLERLLQHATV--KPVVNQVECHPYLNQKRLKEFCEARGVKITXYSPLGS-PD 756
VSNFN + LE +L + KPV NQVECHPY NQ++L +FC+++ + + YS LGS +
Sbjct: 178 VSNFNHRLLEMILNKPGLKYKPVCNQVECHPYFNQRKLLDFCKSKDIVLVAYSALGSHRE 237
Query: 757 RPWGQARRP 783
PW P
Sbjct: 238 EPWVDPNSP 246
Score = 80.6 bits (190), Expect = 7e-15
Identities = 46/115 (40%), Positives = 57/115 (49%), Gaps = 3/115 (2%)
Frame = +3
Query: 66 RSSQAAAQLINKMAPXIPVVXFXXGASXPVFGXGXWXSKP---GXVXXAVKXAIDIGXRH 236
R + + +M V G PV G G + AVK AI+ G H
Sbjct: 2 RKKHLLTRPVTEMDSKYQCVKLNDGHFMPVLGFGTYAPAEVPKSKALEAVKLAIEAGFHH 61
Query: 237 IDCAYVYGNXXXVGXAITSKIKEGVVTRXXLFITSKLWNTFHRPDLVRGALQEXL 401
ID A+VY N VG AI SKI +G V R +F TSKLW+ HRP+LVR AL+ L
Sbjct: 62 IDSAHVYNNEEQVGLAIRSKIADGSVKREDIFYTSKLWSNSHRPELVRPALERSL 116
>AB032153-1|BAA92891.1| 323|Homo sapiens bile acid-binding protein
protein.
Length = 323
Score = 130 bits (314), Expect = 7e-30
Identities = 62/129 (48%), Positives = 82/129 (63%), Gaps = 3/129 (2%)
Frame = +1
Query: 406 NLNVQYLDLYLIHWPQAYKEDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIG 585
NL + Y+DLYLIH+P + K + P D++GKI F VD TW+AME GL KSIG
Sbjct: 105 NLQLDYVDLYLIHFPVSVKPGEEVIPKDENGKILFDTVDLCATWEAMEKCKDAGLAKSIG 164
Query: 586 VSNFNSKQLERLLQHATV--KPVVNQVECHPYLNQKRLKEFCEARGVKITXYSPLGS-PD 756
VSNFN + LE +L + KPV NQVECHPY NQ++L +FC+++ + + YS LGS +
Sbjct: 165 VSNFNHRLLEMILNKPGLKYKPVCNQVECHPYFNQRKLLDFCKSKDIVLVAYSALGSHRE 224
Query: 757 RPWGQARRP 783
PW P
Sbjct: 225 EPWVDPNSP 233
Score = 79.4 bits (187), Expect = 2e-14
Identities = 44/96 (45%), Positives = 52/96 (54%), Gaps = 3/96 (3%)
Frame = +3
Query: 123 VXFXXGASXPVFGXGXWXSKP---GXVXXAVKXAIDIGXRHIDCAYVYGNXXXVGXAITS 293
V G PV G G + AVK AI+ G HID A+VY N VG AI S
Sbjct: 8 VKLNDGHFMPVLGFGTYAPAEVPKSKALEAVKLAIEAGFHHIDSAHVYNNEEQVGLAIRS 67
Query: 294 KIKEGVVTRXXLFITSKLWNTFHRPDLVRGALQEXL 401
KI +G V R +F TSKLW+ HRP+LVR AL+ L
Sbjct: 68 KIADGSVKREDIFYTSKLWSNSHRPELVRPALERSL 103
Score = 37.9 bits (84), Expect = 0.050
Identities = 16/47 (34%), Positives = 27/47 (57%)
Frame = +2
Query: 746 ARRTDPGAKPDDPQXMEDPKLKXIADRLGKTVAQVLIRYQIDXGXIV 886
+ R +P P+ P +EDP L +A + +T A + +RYQ+ G +V
Sbjct: 221 SHREEPWVDPNSPVLLEDPVLCALAKKHKRTPALIALRYQLQRGVVV 267
>AB031084-1|BAA92884.1| 323|Homo sapiens bile acid-binding protein
protein.
Length = 323
Score = 130 bits (314), Expect = 7e-30
Identities = 62/129 (48%), Positives = 82/129 (63%), Gaps = 3/129 (2%)
Frame = +1
Query: 406 NLNVQYLDLYLIHWPQAYKEDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIG 585
NL + Y+DLYLIH+P + K + P D++GKI F VD TW+AME GL KSIG
Sbjct: 105 NLQLDYVDLYLIHFPVSVKPGEEVIPKDENGKILFDTVDLCATWEAMEKCKDAGLAKSIG 164
Query: 586 VSNFNSKQLERLLQHATV--KPVVNQVECHPYLNQKRLKEFCEARGVKITXYSPLGS-PD 756
VSNFN + LE +L + KPV NQVECHPY NQ++L +FC+++ + + YS LGS +
Sbjct: 165 VSNFNHRLLEMILNKPGLKYKPVCNQVECHPYFNQRKLLDFCKSKDIVLVAYSALGSHRE 224
Query: 757 RPWGQARRP 783
PW P
Sbjct: 225 EPWVDPNSP 233
Score = 79.4 bits (187), Expect = 2e-14
Identities = 44/96 (45%), Positives = 52/96 (54%), Gaps = 3/96 (3%)
Frame = +3
Query: 123 VXFXXGASXPVFGXGXWXSKP---GXVXXAVKXAIDIGXRHIDCAYVYGNXXXVGXAITS 293
V G PV G G + AVK AI+ G HID A+VY N VG AI S
Sbjct: 8 VKLNDGHFMPVLGFGTYAPAEVPKSKALEAVKLAIEAGFHHIDSAHVYNNEEQVGLAIRS 67
Query: 294 KIKEGVVTRXXLFITSKLWNTFHRPDLVRGALQEXL 401
KI +G V R +F TSKLW+ HRP+LVR AL+ L
Sbjct: 68 KIADGSVKREDIFYTSKLWSNSHRPELVRPALERSL 103
Score = 37.9 bits (84), Expect = 0.050
Identities = 16/47 (34%), Positives = 27/47 (57%)
Frame = +2
Query: 746 ARRTDPGAKPDDPQXMEDPKLKXIADRLGKTVAQVLIRYQIDXGXIV 886
+ R +P P+ P +EDP L +A + +T A + +RYQ+ G +V
Sbjct: 221 SHREEPWVDPNSPVLLEDPVLCALAKKHKRTPALIALRYQLQRGVVV 267
>AB021654-1|BAA36169.1| 323|Homo sapiens DD2/bile acid-binding
protein/AKR1C2/3alpha-hydroxysteroid dehydrogenase type
3 protein.
Length = 323
Score = 130 bits (314), Expect = 7e-30
Identities = 62/129 (48%), Positives = 82/129 (63%), Gaps = 3/129 (2%)
Frame = +1
Query: 406 NLNVQYLDLYLIHWPQAYKEDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIG 585
NL + Y+DLYLIH+P + K + P D++GKI F VD TW+AME GL KSIG
Sbjct: 105 NLQLDYVDLYLIHFPVSVKPGEEVIPKDENGKILFDTVDLCATWEAMEKCKDAGLAKSIG 164
Query: 586 VSNFNSKQLERLLQHATV--KPVVNQVECHPYLNQKRLKEFCEARGVKITXYSPLGS-PD 756
VSNFN + LE +L + KPV NQVECHPY NQ++L +FC+++ + + YS LGS +
Sbjct: 165 VSNFNHRLLEMILNKPGLKYKPVCNQVECHPYFNQRKLLDFCKSKDIVLVAYSALGSHRE 224
Query: 757 RPWGQARRP 783
PW P
Sbjct: 225 EPWVDPNSP 233
Score = 79.4 bits (187), Expect = 2e-14
Identities = 44/96 (45%), Positives = 52/96 (54%), Gaps = 3/96 (3%)
Frame = +3
Query: 123 VXFXXGASXPVFGXGXWXSKP---GXVXXAVKXAIDIGXRHIDCAYVYGNXXXVGXAITS 293
V G PV G G + AVK AI+ G HID A+VY N VG AI S
Sbjct: 8 VKLNDGHFMPVLGFGTYAPAEVPKSKALEAVKLAIEAGFHHIDSAHVYNNEEQVGLAIRS 67
Query: 294 KIKEGVVTRXXLFITSKLWNTFHRPDLVRGALQEXL 401
KI +G V R +F TSKLW+ HRP+LVR AL+ L
Sbjct: 68 KIADGSVKREDIFYTSKLWSNSHRPELVRPALERSL 103
Score = 37.9 bits (84), Expect = 0.050
Identities = 16/47 (34%), Positives = 27/47 (57%)
Frame = +2
Query: 746 ARRTDPGAKPDDPQXMEDPKLKXIADRLGKTVAQVLIRYQIDXGXIV 886
+ R +P P+ P +EDP L +A + +T A + +RYQ+ G +V
Sbjct: 221 SHREEPWVDPNSPVLLEDPVLCALAKKHKRTPALIALRYQLQRGVVV 267
>L32592-1|AAB38486.1| 323|Homo sapiens dihydrodiol
dehydrogenase/bile acid-binding protein protein.
Length = 323
Score = 130 bits (313), Expect = 9e-30
Identities = 62/129 (48%), Positives = 81/129 (62%), Gaps = 3/129 (2%)
Frame = +1
Query: 406 NLNVQYLDLYLIHWPQAYKEDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIG 585
NL + Y DLYLIH+P + K + P D++GKI F VD TW+AME GL KSIG
Sbjct: 105 NLQLDYADLYLIHFPVSVKPGEEVIPKDENGKILFDTVDLCATWEAMEKCKDAGLAKSIG 164
Query: 586 VSNFNSKQLERLLQHATVK--PVVNQVECHPYLNQKRLKEFCEARGVKITXYSPLGS-PD 756
VSNFN + LE +L +K PV NQVECHPY NQ++L +FC+++ + + YS LGS +
Sbjct: 165 VSNFNHRLLEMILNEPGLKYEPVCNQVECHPYFNQRKLLDFCKSKDIVLVAYSALGSHRE 224
Query: 757 RPWGQARRP 783
PW P
Sbjct: 225 EPWVDPNSP 233
Score = 79.4 bits (187), Expect = 2e-14
Identities = 44/96 (45%), Positives = 52/96 (54%), Gaps = 3/96 (3%)
Frame = +3
Query: 123 VXFXXGASXPVFGXGXWXSKP---GXVXXAVKXAIDIGXRHIDCAYVYGNXXXVGXAITS 293
V G PV G G + AVK AI+ G HID A+VY N VG AI S
Sbjct: 8 VKLNDGHFMPVLGFGTYAPAEVPKSKALEAVKLAIEAGYHHIDSAHVYNNEEQVGLAIRS 67
Query: 294 KIKEGVVTRXXLFITSKLWNTFHRPDLVRGALQEXL 401
KI +G V R +F TSKLW+ HRP+LVR AL+ L
Sbjct: 68 KIADGSVKREDIFYTSKLWSNSHRPELVRPALERSL 103
Score = 37.9 bits (84), Expect = 0.050
Identities = 16/47 (34%), Positives = 27/47 (57%)
Frame = +2
Query: 746 ARRTDPGAKPDDPQXMEDPKLKXIADRLGKTVAQVLIRYQIDXGXIV 886
+ R +P P+ P +EDP L +A + +T A + +RYQ+ G +V
Sbjct: 221 SHREEPWVDPNSPVLLEDPVLCALAKKHKRTPALIALRYQLQRGVVV 267
>S68290-1|AAD14012.1| 320|Homo sapiens chlordecone reductase
homolog protein.
Length = 320
Score = 126 bits (305), Expect = 8e-29
Identities = 61/129 (47%), Positives = 80/129 (62%), Gaps = 3/129 (2%)
Frame = +1
Query: 406 NLNVQYLDLYLIHWPQAYKEDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIG 585
NL + Y+DLYLIH+P + K + P D++GKI F VD TW+A+E L KSIG
Sbjct: 102 NLQLDYVDLYLIHFPVSVKPGEEVIPKDENGKILFDTVDLCATWEAVEKCKDAELAKSIG 161
Query: 586 VSNFNSKQLERLLQH--ATVKPVVNQVECHPYLNQKRLKEFCEARGVKITXYSPLGS-PD 756
VSNFN LE +L VKPV NQVECHPY NQ++L +FC+++ + + YS LGS +
Sbjct: 162 VSNFNRSTLEMILNKPGLQVKPVCNQVECHPYFNQRKLLDFCKSKDIVLVAYSALGSLRE 221
Query: 757 RPWGQARRP 783
PW P
Sbjct: 222 EPWVDPNSP 230
Score = 74.1 bits (174), Expect = 6e-13
Identities = 42/96 (43%), Positives = 50/96 (52%), Gaps = 3/96 (3%)
Frame = +3
Query: 123 VXFXXGASXPVFGXGXWXSKP---GXVXXAVKXAIDIGXRHIDCAYVYGNXXXVGXAITS 293
V G PV G G + A K AI+ G RHID A++Y N VG AI S
Sbjct: 5 VKLNDGHFMPVLGFGTYAPAEVPKSKALEATKLAIEAGFRHIDSAHLYNNEEQVGLAIRS 64
Query: 294 KIKEGVVTRXXLFITSKLWNTFHRPDLVRGALQEXL 401
KI +G V R +F TSKLW HRP+L R AL+ L
Sbjct: 65 KIADGSVKREDIFYTSKLWCNSHRPELDRPALERSL 100
Score = 37.5 bits (83), Expect = 0.066
Identities = 16/45 (35%), Positives = 26/45 (57%)
Frame = +2
Query: 752 RTDPGAKPDDPQXMEDPKLKXIADRLGKTVAQVLIRYQIDXGXIV 886
R +P P+ P +EDP L +A + +T A + +RYQ+ G +V
Sbjct: 220 REEPWVDPNSPVLLEDPVLCALAKKHKRTPALIALRYQLQRGVVV 264
>D17793-1|BAA04619.2| 325|Homo sapiens KIAA0119 protein.
Length = 325
Score = 126 bits (305), Expect = 8e-29
Identities = 61/126 (48%), Positives = 80/126 (63%), Gaps = 3/126 (2%)
Frame = +1
Query: 415 VQYLDLYLIHWPQAYKEDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSN 594
+ Y+DLYLIH P + K L PTD++GK+ F VD TW+AME GL KSIGVSN
Sbjct: 110 LDYVDLYLIHSPMSLKPGEELSPTDENGKVIFDIVDLCTTWEAMEKCKDAGLAKSIGVSN 169
Query: 595 FNSKQLERLLQHATV--KPVVNQVECHPYLNQKRLKEFCEARGVKITXYSPLGSP-DRPW 765
FN +QLE +L + KPV NQVECHPY N+ +L +FC+++ + + YS LGS D+ W
Sbjct: 170 FNRRQLEMILNKPGLKYKPVCNQVECHPYFNRSKLLDFCKSKDIVLVAYSALGSQRDKRW 229
Query: 766 GQARRP 783
P
Sbjct: 230 VDPNSP 235
Score = 83.4 bits (197), Expect = 1e-15
Identities = 44/100 (44%), Positives = 56/100 (56%), Gaps = 3/100 (3%)
Frame = +3
Query: 123 VXFXXGASXPVFGXGXWXSKP---GXVXXAVKXAIDIGXRHIDCAYVYGNXXXVGXAITS 293
V G PV G G + K AI+ G RHID A++Y N VG AI S
Sbjct: 10 VKLNDGHFMPVLGFGTYAPPEVPRSKALEVTKLAIEAGFRHIDSAHLYNNEEQVGLAIRS 69
Query: 294 KIKEGVVTRXXLFITSKLWNTFHRPDLVRGALQEXLXQSE 413
KI +G V R +F TSKLW+TFHRP+LVR AL+ L +++
Sbjct: 70 KIADGSVKREDIFYTSKLWSTFHRPELVRPALENSLKKAQ 109
Score = 33.5 bits (73), Expect = 1.1
Identities = 14/38 (36%), Positives = 23/38 (60%)
Frame = +2
Query: 773 PDDPQXMEDPKLKXIADRLGKTVAQVLIRYQIDXGXIV 886
P+ P +EDP L +A + +T A + +RYQ+ G +V
Sbjct: 232 PNSPVLLEDPVLCALAKKHKRTPALIALRYQLQRGVVV 269
>DQ269985-1|ABB76132.1| 323|Homo sapiens type II 3a-hydroxysteroid
dehydrogenase variant protein.
Length = 323
Score = 126 bits (305), Expect = 8e-29
Identities = 61/126 (48%), Positives = 80/126 (63%), Gaps = 3/126 (2%)
Frame = +1
Query: 415 VQYLDLYLIHWPQAYKEDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSN 594
+ Y+DLYLIH P + K L PTD++GK+ F VD TW+AME GL KSIGVSN
Sbjct: 108 LDYVDLYLIHSPMSLKPGEELSPTDENGKVIFDIVDLCTTWEAMEKCKDAGLAKSIGVSN 167
Query: 595 FNSKQLERLLQHATV--KPVVNQVECHPYLNQKRLKEFCEARGVKITXYSPLGSP-DRPW 765
FN +QLE +L + KPV NQVECHPY N+ +L +FC+++ + + YS LGS D+ W
Sbjct: 168 FNRRQLEMILNKPGLKYKPVCNQVECHPYFNRSKLLDFCKSKDIVLVAYSALGSQRDKRW 227
Query: 766 GQARRP 783
P
Sbjct: 228 VDPNSP 233
Score = 77.8 bits (183), Expect = 5e-14
Identities = 42/100 (42%), Positives = 54/100 (54%), Gaps = 3/100 (3%)
Frame = +3
Query: 123 VXFXXGASXPVFGXGXWXSKP---GXVXXAVKXAIDIGXRHIDCAYVYGNXXXVGXAITS 293
V G PV G G + A K AI+ G RHID A++Y N VG A+ S
Sbjct: 8 VKLNDGHFMPVLGFGTYAPAEVPKSKALEATKLAIEAGFRHIDSAHLYNNEEQVGLAVRS 67
Query: 294 KIKEGVVTRXXLFITSKLWNTFHRPDLVRGALQEXLXQSE 413
KI +G V R +F TSKLW HRP+LVR AL+ L +++
Sbjct: 68 KIADGSVKREDIFYTSKLWCNSHRPELVRPALERSLKKAQ 107
Score = 33.5 bits (73), Expect = 1.1
Identities = 14/38 (36%), Positives = 23/38 (60%)
Frame = +2
Query: 773 PDDPQXMEDPKLKXIADRLGKTVAQVLIRYQIDXGXIV 886
P+ P +EDP L +A + +T A + +RYQ+ G +V
Sbjct: 230 PNSPVLLEDPVLCALAKKHKRTPALIALRYQLQRGVVV 267
>BT007286-1|AAP35950.1| 323|Homo sapiens aldo-keto reductase family
1, member C3 (3-alpha hydroxysteroid dehydrogenase,
protein.
Length = 323
Score = 126 bits (305), Expect = 8e-29
Identities = 61/126 (48%), Positives = 80/126 (63%), Gaps = 3/126 (2%)
Frame = +1
Query: 415 VQYLDLYLIHWPQAYKEDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSN 594
+ Y+DLYLIH P + K L PTD++GK+ F VD TW+AME GL KSIGVSN
Sbjct: 108 LDYVDLYLIHSPMSLKPGEELSPTDENGKVIFDIVDLCTTWEAMEKCKDAGLAKSIGVSN 167
Query: 595 FNSKQLERLLQHATV--KPVVNQVECHPYLNQKRLKEFCEARGVKITXYSPLGSP-DRPW 765
FN +QLE +L + KPV NQVECHPY N+ +L +FC+++ + + YS LGS D+ W
Sbjct: 168 FNRRQLEMILNKPGLKYKPVCNQVECHPYFNRSKLLDFCKSKDIVLVAYSALGSQRDKRW 227
Query: 766 GQARRP 783
P
Sbjct: 228 VDPNSP 233
Score = 83.4 bits (197), Expect = 1e-15
Identities = 44/100 (44%), Positives = 56/100 (56%), Gaps = 3/100 (3%)
Frame = +3
Query: 123 VXFXXGASXPVFGXGXWXSKP---GXVXXAVKXAIDIGXRHIDCAYVYGNXXXVGXAITS 293
V G PV G G + K AI+ G RHID A++Y N VG AI S
Sbjct: 8 VKLNDGHFMPVLGFGTYAPPEVPRSKALEVTKLAIEAGFRHIDSAHLYNNEEQVGLAIRS 67
Query: 294 KIKEGVVTRXXLFITSKLWNTFHRPDLVRGALQEXLXQSE 413
KI +G V R +F TSKLW+TFHRP+LVR AL+ L +++
Sbjct: 68 KIADGSVKREDIFYTSKLWSTFHRPELVRPALENSLKKAQ 107
Score = 33.5 bits (73), Expect = 1.1
Identities = 14/38 (36%), Positives = 23/38 (60%)
Frame = +2
Query: 773 PDDPQXMEDPKLKXIADRLGKTVAQVLIRYQIDXGXIV 886
P+ P +EDP L +A + +T A + +RYQ+ G +V
Sbjct: 230 PNSPVLLEDPVLCALAKKHKRTPALIALRYQLQRGVVV 267
>BC019230-1|AAH19230.1| 323|Homo sapiens aldo-keto reductase family
1, member C3 (3-alpha hydroxysteroid dehydrogenase,
protein.
Length = 323
Score = 126 bits (305), Expect = 8e-29
Identities = 61/126 (48%), Positives = 80/126 (63%), Gaps = 3/126 (2%)
Frame = +1
Query: 415 VQYLDLYLIHWPQAYKEDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSN 594
+ Y+DLYLIH P + K L PTD++GK+ F VD TW+AME GL KSIGVSN
Sbjct: 108 LDYVDLYLIHSPMSLKPGEELSPTDENGKVIFDIVDLCTTWEAMEKCKDAGLAKSIGVSN 167
Query: 595 FNSKQLERLLQHATV--KPVVNQVECHPYLNQKRLKEFCEARGVKITXYSPLGSP-DRPW 765
FN +QLE +L + KPV NQVECHPY N+ +L +FC+++ + + YS LGS D+ W
Sbjct: 168 FNRRQLEMILNKPGLKYKPVCNQVECHPYFNRSKLLDFCKSKDIVLVAYSALGSQRDKRW 227
Query: 766 GQARRP 783
P
Sbjct: 228 VDPNSP 233
Score = 83.4 bits (197), Expect = 1e-15
Identities = 44/100 (44%), Positives = 56/100 (56%), Gaps = 3/100 (3%)
Frame = +3
Query: 123 VXFXXGASXPVFGXGXWXSKP---GXVXXAVKXAIDIGXRHIDCAYVYGNXXXVGXAITS 293
V G PV G G + K AI+ G RHID A++Y N VG AI S
Sbjct: 8 VKLNDGHFMPVLGFGTYAPPEVPRSKALEVTKLAIEAGFRHIDSAHLYNNEEQVGLAIRS 67
Query: 294 KIKEGVVTRXXLFITSKLWNTFHRPDLVRGALQEXLXQSE 413
KI +G V R +F TSKLW+TFHRP+LVR AL+ L +++
Sbjct: 68 KIADGSVKREDIFYTSKLWSTFHRPELVRPALENSLKKAQ 107
Score = 33.5 bits (73), Expect = 1.1
Identities = 14/38 (36%), Positives = 23/38 (60%)
Frame = +2
Query: 773 PDDPQXMEDPKLKXIADRLGKTVAQVLIRYQIDXGXIV 886
P+ P +EDP L +A + +T A + +RYQ+ G +V
Sbjct: 230 PNSPVLLEDPVLCALAKKHKRTPALIALRYQLQRGVVV 267
>BC001479-1|AAH01479.1| 323|Homo sapiens aldo-keto reductase family
1, member C3 (3-alpha hydroxysteroid dehydrogenase,
protein.
Length = 323
Score = 126 bits (305), Expect = 8e-29
Identities = 61/126 (48%), Positives = 80/126 (63%), Gaps = 3/126 (2%)
Frame = +1
Query: 415 VQYLDLYLIHWPQAYKEDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSN 594
+ Y+DLYLIH P + K L PTD++GK+ F VD TW+AME GL KSIGVSN
Sbjct: 108 LDYVDLYLIHSPMSLKPGEELSPTDENGKVIFDIVDLCTTWEAMEKCKDAGLAKSIGVSN 167
Query: 595 FNSKQLERLLQHATV--KPVVNQVECHPYLNQKRLKEFCEARGVKITXYSPLGSP-DRPW 765
FN +QLE +L + KPV NQVECHPY N+ +L +FC+++ + + YS LGS D+ W
Sbjct: 168 FNRRQLEMILNKPGLKYKPVCNQVECHPYFNRSKLLDFCKSKDIVLVAYSALGSQRDKRW 227
Query: 766 GQARRP 783
P
Sbjct: 228 VDPNSP 233
Score = 83.4 bits (197), Expect = 1e-15
Identities = 44/100 (44%), Positives = 56/100 (56%), Gaps = 3/100 (3%)
Frame = +3
Query: 123 VXFXXGASXPVFGXGXWXSKP---GXVXXAVKXAIDIGXRHIDCAYVYGNXXXVGXAITS 293
V G PV G G + K AI+ G RHID A++Y N VG AI S
Sbjct: 8 VKLNDGHFMPVLGFGTYAPPEVPRSKALEVTKLAIEAGFRHIDSAHLYNNEEQVGLAIRS 67
Query: 294 KIKEGVVTRXXLFITSKLWNTFHRPDLVRGALQEXLXQSE 413
KI +G V R +F TSKLW+TFHRP+LVR AL+ L +++
Sbjct: 68 KIADGSVKREDIFYTSKLWSTFHRPELVRPALENSLKKAQ 107
Score = 33.5 bits (73), Expect = 1.1
Identities = 14/38 (36%), Positives = 23/38 (60%)
Frame = +2
Query: 773 PDDPQXMEDPKLKXIADRLGKTVAQVLIRYQIDXGXIV 886
P+ P +EDP L +A + +T A + +RYQ+ G +V
Sbjct: 230 PNSPVLLEDPVLCALAKKHKRTPALIALRYQLQRGVVV 267
>AL391427-4|CAI14729.1| 323|Homo sapiens aldo-keto reductase family
1, member C3 (3-alpha hydroxysteroid dehydrogenase,
protein.
Length = 323
Score = 126 bits (305), Expect = 8e-29
Identities = 61/126 (48%), Positives = 80/126 (63%), Gaps = 3/126 (2%)
Frame = +1
Query: 415 VQYLDLYLIHWPQAYKEDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSN 594
+ Y+DLYLIH P + K L PTD++GK+ F VD TW+AME GL KSIGVSN
Sbjct: 108 LDYVDLYLIHSPMSLKPGEELSPTDENGKVIFDIVDLCTTWEAMEKCKDAGLAKSIGVSN 167
Query: 595 FNSKQLERLLQHATV--KPVVNQVECHPYLNQKRLKEFCEARGVKITXYSPLGSP-DRPW 765
FN +QLE +L + KPV NQVECHPY N+ +L +FC+++ + + YS LGS D+ W
Sbjct: 168 FNRRQLEMILNKPGLKYKPVCNQVECHPYFNRSKLLDFCKSKDIVLVAYSALGSQRDKRW 227
Query: 766 GQARRP 783
P
Sbjct: 228 VDPNSP 233
Score = 83.4 bits (197), Expect = 1e-15
Identities = 44/100 (44%), Positives = 56/100 (56%), Gaps = 3/100 (3%)
Frame = +3
Query: 123 VXFXXGASXPVFGXGXWXSKP---GXVXXAVKXAIDIGXRHIDCAYVYGNXXXVGXAITS 293
V G PV G G + K AI+ G RHID A++Y N VG AI S
Sbjct: 8 VKLNDGHFMPVLGFGTYAPPEVPRSKALEVTKLAIEAGFRHIDSAHLYNNEEQVGLAIRS 67
Query: 294 KIKEGVVTRXXLFITSKLWNTFHRPDLVRGALQEXLXQSE 413
KI +G V R +F TSKLW+TFHRP+LVR AL+ L +++
Sbjct: 68 KIADGSVKREDIFYTSKLWSTFHRPELVRPALENSLKKAQ 107
Score = 33.5 bits (73), Expect = 1.1
Identities = 14/38 (36%), Positives = 23/38 (60%)
Frame = +2
Query: 773 PDDPQXMEDPKLKXIADRLGKTVAQVLIRYQIDXGXIV 886
P+ P +EDP L +A + +T A + +RYQ+ G +V
Sbjct: 230 PNSPVLLEDPVLCALAKKHKRTPALIALRYQLQRGVVV 267
>AF149416-1|AAF07272.2| 323|Homo sapiens 3-alpha hydroxysteroid
dehydrogenase type IIb protein.
Length = 323
Score = 126 bits (305), Expect = 8e-29
Identities = 61/126 (48%), Positives = 80/126 (63%), Gaps = 3/126 (2%)
Frame = +1
Query: 415 VQYLDLYLIHWPQAYKEDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSN 594
+ Y+DLYLIH P + K L PTD++GK+ F VD TW+AME GL KSIGVSN
Sbjct: 108 LDYVDLYLIHSPMSLKPGEELSPTDENGKVIFDIVDLCTTWEAMEKCKDAGLAKSIGVSN 167
Query: 595 FNSKQLERLLQHATV--KPVVNQVECHPYLNQKRLKEFCEARGVKITXYSPLGSP-DRPW 765
FN +QLE +L + KPV NQVECHPY N+ +L +FC+++ + + YS LGS D+ W
Sbjct: 168 FNRRQLEMILNKPGLKYKPVCNQVECHPYFNRSKLLDFCKSKDIVLVAYSALGSQRDKRW 227
Query: 766 GQARRP 783
P
Sbjct: 228 VDPNSP 233
Score = 79.8 bits (188), Expect = 1e-14
Identities = 44/100 (44%), Positives = 57/100 (57%), Gaps = 3/100 (3%)
Frame = +3
Query: 123 VXFXXGASXPVFGXGXWXSKPGXVXXAV---KXAIDIGXRHIDCAYVYGNXXXVGXAITS 293
V G PV G G + A+ K AI+ G RHID A++Y N VG AI S
Sbjct: 8 VKLNDGHFMPVLGFGTYAPPEVPRSKALEVSKLAIEAGFRHIDSAHLYNNEEQVGLAIRS 67
Query: 294 KIKEGVVTRXXLFITSKLWNTFHRPDLVRGALQEXLXQSE 413
KI +G V R +F TSKLW+T HRP+LVR AL+ L +++
Sbjct: 68 KIADGSVKREDIFYTSKLWSTSHRPELVRPALENSLKKAQ 107
Score = 33.5 bits (73), Expect = 1.1
Identities = 14/38 (36%), Positives = 23/38 (60%)
Frame = +2
Query: 773 PDDPQXMEDPKLKXIADRLGKTVAQVLIRYQIDXGXIV 886
P+ P +EDP L +A + +T A + +RYQ+ G +V
Sbjct: 230 PNSPVLLEDPVLCALAKKHKRTPALIALRYQLQRGVVV 267
>AB032157-1|BAA92892.1| 323|Homo sapiens prostaglandin F synthase
protein.
Length = 323
Score = 126 bits (305), Expect = 8e-29
Identities = 61/126 (48%), Positives = 80/126 (63%), Gaps = 3/126 (2%)
Frame = +1
Query: 415 VQYLDLYLIHWPQAYKEDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSN 594
+ Y+DLYLIH P + K L PTD++GK+ F VD TW+AME GL KSIGVSN
Sbjct: 108 LDYVDLYLIHSPMSLKPGEELSPTDENGKVIFDIVDLCTTWEAMEKCKDAGLAKSIGVSN 167
Query: 595 FNSKQLERLLQHATV--KPVVNQVECHPYLNQKRLKEFCEARGVKITXYSPLGSP-DRPW 765
FN +QLE +L + KPV NQVECHPY N+ +L +FC+++ + + YS LGS D+ W
Sbjct: 168 FNRRQLEMILNKPGLKYKPVCNQVECHPYFNRSKLLDFCKSKDIVLVAYSALGSQRDKRW 227
Query: 766 GQARRP 783
P
Sbjct: 228 VDPNSP 233
Score = 83.4 bits (197), Expect = 1e-15
Identities = 44/100 (44%), Positives = 56/100 (56%), Gaps = 3/100 (3%)
Frame = +3
Query: 123 VXFXXGASXPVFGXGXWXSKP---GXVXXAVKXAIDIGXRHIDCAYVYGNXXXVGXAITS 293
V G PV G G + K AI+ G RHID A++Y N VG AI S
Sbjct: 8 VKLNDGHFMPVLGFGTYAPPEVPRSKALEVTKLAIEAGFRHIDSAHLYNNEEQVGLAIRS 67
Query: 294 KIKEGVVTRXXLFITSKLWNTFHRPDLVRGALQEXLXQSE 413
KI +G V R +F TSKLW+TFHRP+LVR AL+ L +++
Sbjct: 68 KIADGSVKREDIFYTSKLWSTFHRPELVRPALENSLKKAQ 107
Score = 33.5 bits (73), Expect = 1.1
Identities = 14/38 (36%), Positives = 23/38 (60%)
Frame = +2
Query: 773 PDDPQXMEDPKLKXIADRLGKTVAQVLIRYQIDXGXIV 886
P+ P +EDP L +A + +T A + +RYQ+ G +V
Sbjct: 230 PNSPVLLEDPVLCALAKKHKRTPALIALRYQLQRGVVV 267
>AB018580-1|BAA88488.1| 323|Homo sapiens hluPGFS protein.
Length = 323
Score = 126 bits (305), Expect = 8e-29
Identities = 61/126 (48%), Positives = 80/126 (63%), Gaps = 3/126 (2%)
Frame = +1
Query: 415 VQYLDLYLIHWPQAYKEDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSN 594
+ Y+DLYLIH P + K L PTD++GK+ F VD TW+AME GL KSIGVSN
Sbjct: 108 LDYVDLYLIHSPMSLKPGEELSPTDENGKVIFDIVDLCTTWEAMEKCKDAGLAKSIGVSN 167
Query: 595 FNSKQLERLLQHATV--KPVVNQVECHPYLNQKRLKEFCEARGVKITXYSPLGSP-DRPW 765
FN +QLE +L + KPV NQVECHPY N+ +L +FC+++ + + YS LGS D+ W
Sbjct: 168 FNRRQLEMILNKPGLKYKPVCNQVECHPYFNRSKLLDFCKSKDIVLVAYSALGSQRDKRW 227
Query: 766 GQARRP 783
P
Sbjct: 228 VDPNSP 233
Score = 83.4 bits (197), Expect = 1e-15
Identities = 44/100 (44%), Positives = 56/100 (56%), Gaps = 3/100 (3%)
Frame = +3
Query: 123 VXFXXGASXPVFGXGXWXSKP---GXVXXAVKXAIDIGXRHIDCAYVYGNXXXVGXAITS 293
V G PV G G + K AI+ G RHID A++Y N VG AI S
Sbjct: 8 VKLNDGHFMPVLGFGTYAPPEVPRSKALEVTKLAIEAGFRHIDSAHLYNNEEQVGLAIRS 67
Query: 294 KIKEGVVTRXXLFITSKLWNTFHRPDLVRGALQEXLXQSE 413
KI +G V R +F TSKLW+TFHRP+LVR AL+ L +++
Sbjct: 68 KIADGSVKREDIFYTSKLWSTFHRPELVRPALENSLKKAQ 107
Score = 33.5 bits (73), Expect = 1.1
Identities = 14/38 (36%), Positives = 23/38 (60%)
Frame = +2
Query: 773 PDDPQXMEDPKLKXIADRLGKTVAQVLIRYQIDXGXIV 886
P+ P +EDP L +A + +T A + +RYQ+ G +V
Sbjct: 230 PNSPVLLEDPVLCALAKKHKRTPALIALRYQLQRGVVV 267
>S68288-1|AAD14011.1| 323|Homo sapiens chlordecone reductase
homolog protein.
Length = 323
Score = 126 bits (303), Expect = 1e-28
Identities = 61/126 (48%), Positives = 80/126 (63%), Gaps = 3/126 (2%)
Frame = +1
Query: 415 VQYLDLYLIHWPQAYKEDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSN 594
+ Y+DLYLIH P + K L PTD++GK+ F VD TW+AME GL KSIGVSN
Sbjct: 108 LDYVDLYLIHSPMSLKPGEELSPTDENGKVIFDIVDLCTTWEAMEKCKDAGLAKSIGVSN 167
Query: 595 FNSKQLERLLQHATV--KPVVNQVECHPYLNQKRLKEFCEARGVKITXYSPLGSP-DRPW 765
FN +QLE +L + KPV NQVECHPY N+ +L +FC+++ + + YS LGS D+ W
Sbjct: 168 FNRRQLEIILNKPGLKYKPVCNQVECHPYFNRSKLLDFCKSKDIVLVAYSALGSQRDKRW 227
Query: 766 GQARRP 783
P
Sbjct: 228 VDPNSP 233
Score = 83.4 bits (197), Expect = 1e-15
Identities = 44/100 (44%), Positives = 56/100 (56%), Gaps = 3/100 (3%)
Frame = +3
Query: 123 VXFXXGASXPVFGXGXWXSKP---GXVXXAVKXAIDIGXRHIDCAYVYGNXXXVGXAITS 293
V G PV G G + K AI+ G RHID A++Y N VG AI S
Sbjct: 8 VKLNDGHFMPVLGFGTYAPPEVPRSKALEVTKLAIEAGFRHIDSAHLYNNEEQVGLAIRS 67
Query: 294 KIKEGVVTRXXLFITSKLWNTFHRPDLVRGALQEXLXQSE 413
KI +G V R +F TSKLW+TFHRP+LVR AL+ L +++
Sbjct: 68 KIADGSVEREDIFYTSKLWSTFHRPELVRPALENSLKKAQ 107
Score = 33.5 bits (73), Expect = 1.1
Identities = 14/38 (36%), Positives = 23/38 (60%)
Frame = +2
Query: 773 PDDPQXMEDPKLKXIADRLGKTVAQVLIRYQIDXGXIV 886
P+ P +EDP L +A + +T A + +RYQ+ G +V
Sbjct: 230 PNSPVLLEDPVLCALAKKHKRTPALIALRYQLQRGVVV 267
>L43839-1|AAB41916.1| 323|Homo sapiens 3-alpha-hydroxysteroid
dehydrogenase protein.
Length = 323
Score = 126 bits (303), Expect = 1e-28
Identities = 61/126 (48%), Positives = 80/126 (63%), Gaps = 3/126 (2%)
Frame = +1
Query: 415 VQYLDLYLIHWPQAYKEDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSN 594
+ Y+DLYLIH P + K L PTD++GK+ F VD TW+AME GL KSIGVSN
Sbjct: 108 LDYVDLYLIHSPMSLKPGEELSPTDENGKVIFDIVDLCTTWEAMEKCKDAGLAKSIGVSN 167
Query: 595 FNSKQLERLLQHATV--KPVVNQVECHPYLNQKRLKEFCEARGVKITXYSPLGSP-DRPW 765
FN +QLE +L + KPV NQVECHPY N+ +L +FC+++ + + YS LGS D+ W
Sbjct: 168 FNRRQLEIILNKPGLKYKPVCNQVECHPYFNRSKLLDFCKSKDIVLVAYSALGSQRDKRW 227
Query: 766 GQARRP 783
P
Sbjct: 228 VDPNSP 233
Score = 83.4 bits (197), Expect = 1e-15
Identities = 44/100 (44%), Positives = 56/100 (56%), Gaps = 3/100 (3%)
Frame = +3
Query: 123 VXFXXGASXPVFGXGXWXSKP---GXVXXAVKXAIDIGXRHIDCAYVYGNXXXVGXAITS 293
V G PV G G + K AI+ G RHID A++Y N VG AI S
Sbjct: 8 VKLNDGHFMPVLGFGTYAPPEVPRSKALEVTKLAIEAGFRHIDSAHLYNNEEQVGLAIRS 67
Query: 294 KIKEGVVTRXXLFITSKLWNTFHRPDLVRGALQEXLXQSE 413
KI +G V R +F TSKLW+TFHRP+LVR AL+ L +++
Sbjct: 68 KIADGSVMREDIFYTSKLWSTFHRPELVRPALENSLKKAQ 107
Score = 33.5 bits (73), Expect = 1.1
Identities = 14/38 (36%), Positives = 23/38 (60%)
Frame = +2
Query: 773 PDDPQXMEDPKLKXIADRLGKTVAQVLIRYQIDXGXIV 886
P+ P +EDP L +A + +T A + +RYQ+ G +V
Sbjct: 230 PNSPVLLEDPVLCALAKKHKRTPALIALRYQLQRGVVV 267
>BC002862-1|AAH02862.1| 307|Homo sapiens AKR1CL2 protein protein.
Length = 307
Score = 125 bits (302), Expect = 2e-28
Identities = 67/141 (47%), Positives = 83/141 (58%), Gaps = 21/141 (14%)
Frame = +1
Query: 388 CRXPWXNLNVQYLDLYLIHWPQAYKEDGSLF-------------------PTDQSGKIQF 510
CR L + YLDLYLIHWP +K + P D+S +
Sbjct: 84 CRKSLKALKLNYLDLYLIHWPMGFKPPHPEWIMSCSELSFCLSHPRVQDLPLDESNMVIP 143
Query: 511 SDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQHATV--KPVVNQVECHPYLNQ 684
SD D++DTW+AME LV GLVK+IGVSNFN +QLERLL + KP+ NQ+ECHPYL Q
Sbjct: 144 SDTDFLDTWEAMEDLVITGLVKNIGVSNFNHEQLERLLNKPGLRFKPLTNQIECHPYLTQ 203
Query: 685 KRLKEFCEARGVKITXYSPLG 747
K L FC++R V +T Y PLG
Sbjct: 204 KNLISFCQSRDVSVTAYRPLG 224
Score = 89.0 bits (211), Expect = 2e-17
Identities = 43/84 (51%), Positives = 48/84 (57%)
Frame = +3
Query: 150 PVFGXGXWXSKPGXVXXAVKXAIDIGXRHIDCAYVYGNXXXVGXAITSKIKEGVVTRXXL 329
P G W + PG V AVK AID G RH DCAY Y N VG I KIKEG V R L
Sbjct: 5 PAVGLSSWKASPGKVTEAVKEAIDAGYRHFDCAYFYHNEREVGAGIRCKIKEGAVRREDL 64
Query: 330 FITSKLWNTFHRPDLVRGALQEXL 401
FI +KLW T H+ LV A ++ L
Sbjct: 65 FIATKLWCTCHKKSLVETACRKSL 88
Score = 35.9 bits (79), Expect = 0.20
Identities = 17/43 (39%), Positives = 25/43 (58%)
Frame = +2
Query: 764 GAKPDDPQXMEDPKLKXIADRLGKTVAQVLIRYQIDXGXIVXP 892
G + +++P +K IA GK+ AQ+LIR+QI IV P
Sbjct: 224 GGSCEGVDLIDNPVIKRIAKEHGKSPAQILIRFQIQRNVIVIP 266
>AF263242-1|AAK58523.1| 320|Homo sapiens aldo-keto reductase
loopADR protein.
Length = 320
Score = 125 bits (302), Expect = 2e-28
Identities = 67/141 (47%), Positives = 83/141 (58%), Gaps = 21/141 (14%)
Frame = +1
Query: 388 CRXPWXNLNVQYLDLYLIHWPQAYKEDGSLF-------------------PTDQSGKIQF 510
CR L + YLDLYLIHWP +K + P D+S +
Sbjct: 84 CRKSLKALKLNYLDLYLIHWPMGFKPPHPEWIMSCSELSFCLSHPRVQDLPLDESNMVIP 143
Query: 511 SDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQHATV--KPVVNQVECHPYLNQ 684
SD D++DTW+AME LV GLVK+IGVSNFN +QLERLL + KP+ NQ+ECHPYL Q
Sbjct: 144 SDTDFLDTWEAMEDLVITGLVKNIGVSNFNHEQLERLLNKPGLRFKPLTNQIECHPYLTQ 203
Query: 685 KRLKEFCEARGVKITXYSPLG 747
K L FC++R V +T Y PLG
Sbjct: 204 KNLISFCQSRDVSVTAYRPLG 224
Score = 89.0 bits (211), Expect = 2e-17
Identities = 43/84 (51%), Positives = 48/84 (57%)
Frame = +3
Query: 150 PVFGXGXWXSKPGXVXXAVKXAIDIGXRHIDCAYVYGNXXXVGXAITSKIKEGVVTRXXL 329
P G W + PG V AVK AID G RH DCAY Y N VG I KIKEG V R L
Sbjct: 5 PAVGLSSWKASPGKVTEAVKEAIDAGYRHFDCAYFYHNEREVGAGIRCKIKEGAVRREDL 64
Query: 330 FITSKLWNTFHRPDLVRGALQEXL 401
FI +KLW T H+ LV A ++ L
Sbjct: 65 FIATKLWCTCHKKSLVETACRKSL 88
Score = 35.9 bits (79), Expect = 0.20
Identities = 17/43 (39%), Positives = 25/43 (58%)
Frame = +2
Query: 764 GAKPDDPQXMEDPKLKXIADRLGKTVAQVLIRYQIDXGXIVXP 892
G + +++P +K IA GK+ AQ+LIR+QI IV P
Sbjct: 224 GGSCEGVDLIDNPVIKRIAKEHGKSPAQILIRFQIQRNVIVIP 266
>AB055603-1|BAC54568.1| 307|Homo sapiens aldo-keto reductase
related protein 4 protein.
Length = 307
Score = 125 bits (302), Expect = 2e-28
Identities = 67/141 (47%), Positives = 83/141 (58%), Gaps = 21/141 (14%)
Frame = +1
Query: 388 CRXPWXNLNVQYLDLYLIHWPQAYKEDGSLF-------------------PTDQSGKIQF 510
CR L + YLDLYLIHWP +K + P D+S +
Sbjct: 84 CRKSLKALKLNYLDLYLIHWPMGFKPPHPEWIMSCSELSFCLSHPRVQDLPLDESNMVIP 143
Query: 511 SDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQHATV--KPVVNQVECHPYLNQ 684
SD D++DTW+AME LV GLVK+IGVSNFN +QLERLL + KP+ NQ+ECHPYL Q
Sbjct: 144 SDTDFLDTWEAMEDLVITGLVKNIGVSNFNHEQLERLLNKPGLRFKPLTNQIECHPYLTQ 203
Query: 685 KRLKEFCEARGVKITXYSPLG 747
K L FC++R V +T Y PLG
Sbjct: 204 KNLISFCQSRDVSVTAYRPLG 224
Score = 89.0 bits (211), Expect = 2e-17
Identities = 43/84 (51%), Positives = 48/84 (57%)
Frame = +3
Query: 150 PVFGXGXWXSKPGXVXXAVKXAIDIGXRHIDCAYVYGNXXXVGXAITSKIKEGVVTRXXL 329
P G W + PG V AVK AID G RH DCAY Y N VG I KIKEG V R L
Sbjct: 5 PAVGLSSWKASPGKVTEAVKEAIDAGYRHFDCAYFYHNEREVGAGIRCKIKEGAVRREDL 64
Query: 330 FITSKLWNTFHRPDLVRGALQEXL 401
FI +KLW T H+ LV A ++ L
Sbjct: 65 FIATKLWCTCHKKSLVETACRKSL 88
Score = 35.9 bits (79), Expect = 0.20
Identities = 17/43 (39%), Positives = 25/43 (58%)
Frame = +2
Query: 764 GAKPDDPQXMEDPKLKXIADRLGKTVAQVLIRYQIDXGXIVXP 892
G + +++P +K IA GK+ AQ+LIR+QI IV P
Sbjct: 224 GGSCEGVDLIDNPVIKRIAKEHGKSPAQILIRFQIQRNVIVIP 266
>Z28339-1|CAA82193.1| 326|Homo sapiens delta 4-3-oxosteroid 5
beta-reductase protein.
Length = 326
Score = 123 bits (296), Expect = 1e-27
Identities = 59/129 (45%), Positives = 79/129 (61%), Gaps = 3/129 (2%)
Frame = +1
Query: 409 LNVQYLDLYLIHWPQAYKEDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGV 588
L + Y+DLY+I P A+K ++P D++GK + + TW+AME GLVKS+GV
Sbjct: 109 LQLDYVDLYIIEVPMAFKPGDEIYPRDENGKWLYHKSNLCATWEAMEACKDAGLVKSLGV 168
Query: 589 SNFNSKQLERLLQHATV--KPVVNQVECHPYLNQKRLKEFCEARGVKITXYSPLGSPDRP 762
SNFN +QLE +L + KPV NQVECHPY Q +L +FC+ + IT YSPLG+ P
Sbjct: 169 SNFNRRQLELILNKPGLKHKPVSNQVECHPYFTQPKLLKFCQQHDIVITAYSPLGTSRNP 228
Query: 763 -WGQARRPP 786
W PP
Sbjct: 229 IWVNVSSPP 237
Score = 76.6 bits (180), Expect = 1e-13
Identities = 43/92 (46%), Positives = 51/92 (55%), Gaps = 4/92 (4%)
Frame = +3
Query: 138 GASXPVFGXGXWX---SKP-GXVXXAVKXAIDIGXRHIDCAYVYGNXXXVGXAITSKIKE 305
G S P+ G G + S P G +VK AID G RHID AY+Y N VG AI KI E
Sbjct: 15 GNSIPIIGLGTYSEPKSTPKGACATSVKVAIDTGYRHIDGAYIYQNEHEVGEAIREKIAE 74
Query: 306 GVVTRXXLFITSKLWNTFHRPDLVRGALQEXL 401
G V R +F KLW T H P++VR L+ L
Sbjct: 75 GKVRREDIFYCGKLWATNHVPEMVRPTLERTL 106
>BC130627-1|AAI30628.1| 326|Homo sapiens aldo-keto reductase family
1, member D1 (delta 4-3-ketosteroid-5-beta-reductase
protein.
Length = 326
Score = 123 bits (296), Expect = 1e-27
Identities = 59/129 (45%), Positives = 79/129 (61%), Gaps = 3/129 (2%)
Frame = +1
Query: 409 LNVQYLDLYLIHWPQAYKEDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGV 588
L + Y+DLY+I P A+K ++P D++GK + + TW+AME GLVKS+GV
Sbjct: 109 LQLDYVDLYIIEVPMAFKPGDEIYPRDENGKWLYHKSNLCATWEAMEACKDAGLVKSLGV 168
Query: 589 SNFNSKQLERLLQHATV--KPVVNQVECHPYLNQKRLKEFCEARGVKITXYSPLGSPDRP 762
SNFN +QLE +L + KPV NQVECHPY Q +L +FC+ + IT YSPLG+ P
Sbjct: 169 SNFNRRQLELILNKPGLKHKPVSNQVECHPYFTQPKLLKFCQQHDIVITAYSPLGTSRNP 228
Query: 763 -WGQARRPP 786
W PP
Sbjct: 229 IWVNVSSPP 237
Score = 76.6 bits (180), Expect = 1e-13
Identities = 43/92 (46%), Positives = 51/92 (55%), Gaps = 4/92 (4%)
Frame = +3
Query: 138 GASXPVFGXGXWX---SKP-GXVXXAVKXAIDIGXRHIDCAYVYGNXXXVGXAITSKIKE 305
G S P+ G G + S P G +VK AID G RHID AY+Y N VG AI KI E
Sbjct: 15 GNSIPIIGLGTYSEPKSTPKGACATSVKVAIDTGYRHIDGAYIYQNEHEVGEAIREKIAE 74
Query: 306 GVVTRXXLFITSKLWNTFHRPDLVRGALQEXL 401
G V R +F KLW T H P++VR L+ L
Sbjct: 75 GKVRREDIFYCGKLWATNHVPEMVRPTLERTL 106
>BC130625-1|AAI30626.1| 326|Homo sapiens aldo-keto reductase family
1, member D1 (delta 4-3-ketosteroid-5-beta-reductase
protein.
Length = 326
Score = 123 bits (296), Expect = 1e-27
Identities = 59/129 (45%), Positives = 79/129 (61%), Gaps = 3/129 (2%)
Frame = +1
Query: 409 LNVQYLDLYLIHWPQAYKEDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGV 588
L + Y+DLY+I P A+K ++P D++GK + + TW+AME GLVKS+GV
Sbjct: 109 LQLDYVDLYIIEVPMAFKPGDEIYPRDENGKWLYHKSNLCATWEAMEACKDAGLVKSLGV 168
Query: 589 SNFNSKQLERLLQHATV--KPVVNQVECHPYLNQKRLKEFCEARGVKITXYSPLGSPDRP 762
SNFN +QLE +L + KPV NQVECHPY Q +L +FC+ + IT YSPLG+ P
Sbjct: 169 SNFNRRQLELILNKPGLKHKPVSNQVECHPYFTQPKLLKFCQQHDIVITAYSPLGTSRNP 228
Query: 763 -WGQARRPP 786
W PP
Sbjct: 229 IWVNVSSPP 237
Score = 76.6 bits (180), Expect = 1e-13
Identities = 43/92 (46%), Positives = 51/92 (55%), Gaps = 4/92 (4%)
Frame = +3
Query: 138 GASXPVFGXGXWX---SKP-GXVXXAVKXAIDIGXRHIDCAYVYGNXXXVGXAITSKIKE 305
G S P+ G G + S P G +VK AID G RHID AY+Y N VG AI KI E
Sbjct: 15 GNSIPIIGLGTYSEPKSTPKGACATSVKVAIDTGYRHIDGAYIYQNEHEVGEAIREKIAE 74
Query: 306 GVVTRXXLFITSKLWNTFHRPDLVRGALQEXL 401
G V R +F KLW T H P++VR L+ L
Sbjct: 75 GKVRREDIFYCGKLWATNHVPEMVRPTLERTL 106
>AF283659-1|AAG39381.1| 326|Homo sapiens 5-beta steroid reductase
protein.
Length = 326
Score = 123 bits (296), Expect = 1e-27
Identities = 59/129 (45%), Positives = 79/129 (61%), Gaps = 3/129 (2%)
Frame = +1
Query: 409 LNVQYLDLYLIHWPQAYKEDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGV 588
L + Y+DLY+I P A+K ++P D++GK + + TW+AME GLVKS+GV
Sbjct: 109 LQLDYVDLYIIEVPMAFKPGDEIYPRDENGKWLYHKSNLCATWEAMEACKDAGLVKSLGV 168
Query: 589 SNFNSKQLERLLQHATV--KPVVNQVECHPYLNQKRLKEFCEARGVKITXYSPLGSPDRP 762
SNFN +QLE +L + KPV NQVECHPY Q +L +FC+ + IT YSPLG+ P
Sbjct: 169 SNFNRRQLELILNKPGLKHKPVSNQVECHPYFTQPKLLKFCQQHDIVITAYSPLGTSRNP 228
Query: 763 -WGQARRPP 786
W PP
Sbjct: 229 IWVNVSSPP 237
Score = 76.6 bits (180), Expect = 1e-13
Identities = 43/92 (46%), Positives = 51/92 (55%), Gaps = 4/92 (4%)
Frame = +3
Query: 138 GASXPVFGXGXWX---SKP-GXVXXAVKXAIDIGXRHIDCAYVYGNXXXVGXAITSKIKE 305
G S P+ G G + S P G +VK AID G RHID AY+Y N VG AI KI E
Sbjct: 15 GNSIPIIGLGTYSEPKSTPKGACATSVKVAIDTGYRHIDGAYIYQNEHEVGEAIREKIAE 74
Query: 306 GVVTRXXLFITSKLWNTFHRPDLVRGALQEXL 401
G V R +F KLW T H P++VR L+ L
Sbjct: 75 GKVRREDIFYCGKLWATNHVPEMVRPTLERTL 106
>AB045829-1|BAA99542.1| 323|Homo sapiens 3alpha-hydroxysteroid
dehydrogenase variant protein.
Length = 323
Score = 122 bits (294), Expect = 2e-27
Identities = 56/116 (48%), Positives = 77/116 (66%), Gaps = 2/116 (1%)
Frame = +1
Query: 409 LNVQYLDLYLIHWPQAYKEDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGV 588
L + Y+DLYL+H+P A K + P D++GK+ F VD TW+ ME GL KSIGV
Sbjct: 106 LQLDYVDLYLLHFPMALKPGETPLPKDENGKVIFDTVDLCATWEVMEKCKDAGLAKSIGV 165
Query: 589 SNFNSKQLERLLQHATV--KPVVNQVECHPYLNQKRLKEFCEARGVKITXYSPLGS 750
SNFN +QLE +L + KPV NQVECHPYLNQ +L +FC+++ + + +S LG+
Sbjct: 166 SNFNCRQLEMILNKPGLKYKPVCNQVECHPYLNQSKLLDFCKSKDIVLVAHSALGT 221
Score = 76.6 bits (180), Expect = 1e-13
Identities = 45/103 (43%), Positives = 54/103 (52%), Gaps = 3/103 (2%)
Frame = +3
Query: 102 MAPXIPVVXFXXGASXPVFGXGXWXSKPGXVXXAV---KXAIDIGXRHIDCAYVYGNXXX 272
M P V G PV G G + AV K AI+ G RHID AY+Y N
Sbjct: 1 MDPKYQRVELNDGHFMPVLGFGTYAPPEVPRNRAVEVTKLAIEAGFRHIDSAYLYNNEEQ 60
Query: 273 VGXAITSKIKEGVVTRXXLFITSKLWNTFHRPDLVRGALQEXL 401
VG AI SKI +G V R +F TSKLW TF +P +V+ AL+ L
Sbjct: 61 VGLAIRSKIADGSVKREDIFYTSKLWCTFFQPQMVQPALESSL 103
Score = 33.5 bits (73), Expect = 1.1
Identities = 14/38 (36%), Positives = 23/38 (60%)
Frame = +2
Query: 773 PDDPQXMEDPKLKXIADRLGKTVAQVLIRYQIDXGXIV 886
P+ P +EDP L +A + +T A + +RYQ+ G +V
Sbjct: 230 PNSPVLLEDPVLCALAKKHKRTPALIALRYQLQRGVVV 267
>S68287-1|AAD14010.1| 323|Homo sapiens chlordecone reductase
protein.
Length = 323
Score = 122 bits (293), Expect = 2e-27
Identities = 56/116 (48%), Positives = 77/116 (66%), Gaps = 2/116 (1%)
Frame = +1
Query: 409 LNVQYLDLYLIHWPQAYKEDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGV 588
L + Y+DLYL+H+P A K + P D++GK+ F VD TW+ ME GL KSIGV
Sbjct: 106 LQLDYVDLYLLHFPMALKPGETPLPKDENGKVIFDTVDLSATWEVMEKCKDAGLAKSIGV 165
Query: 589 SNFNSKQLERLLQHATV--KPVVNQVECHPYLNQKRLKEFCEARGVKITXYSPLGS 750
SNFN +QLE +L + KPV NQVECHPYLNQ +L +FC+++ + + +S LG+
Sbjct: 166 SNFNCRQLEMILNKPGLKYKPVCNQVECHPYLNQSKLLDFCKSKDIVLVAHSALGT 221
Score = 76.6 bits (180), Expect = 1e-13
Identities = 45/103 (43%), Positives = 54/103 (52%), Gaps = 3/103 (2%)
Frame = +3
Query: 102 MAPXIPVVXFXXGASXPVFGXGXWXSKPGXVXXAV---KXAIDIGXRHIDCAYVYGNXXX 272
M P V G PV G G + AV K AI+ G RHID AY+Y N
Sbjct: 1 MDPKYQRVELNDGHFMPVLGFGTYAPPEVPRNRAVEVTKLAIEAGFRHIDSAYLYNNEEQ 60
Query: 273 VGXAITSKIKEGVVTRXXLFITSKLWNTFHRPDLVRGALQEXL 401
VG AI SKI +G V R +F TSKLW TF +P +V+ AL+ L
Sbjct: 61 VGLAIRSKIADGSVKREDIFYTSKLWCTFFQPQMVQPALESSL 103
Score = 33.5 bits (73), Expect = 1.1
Identities = 14/38 (36%), Positives = 23/38 (60%)
Frame = +2
Query: 773 PDDPQXMEDPKLKXIADRLGKTVAQVLIRYQIDXGXIV 886
P+ P +EDP L +A + +T A + +RYQ+ G +V
Sbjct: 230 PNSPVLLEDPVLCALAKKHKRTPALIALRYQLQRGVVV 267
>M33375-1|AAA35658.1| 308|Homo sapiens protein ( Human chlordecone
reductase mRNA, complete cds. ).
Length = 308
Score = 122 bits (293), Expect = 2e-27
Identities = 56/116 (48%), Positives = 77/116 (66%), Gaps = 2/116 (1%)
Frame = +1
Query: 409 LNVQYLDLYLIHWPQAYKEDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGV 588
L + Y+DLYL+H+P A K + P D++GK+ F VD TW+ ME GL KSIGV
Sbjct: 91 LQLDYVDLYLLHFPMALKPGETPLPKDENGKVIFDTVDLSATWEVMEKCKDAGLAKSIGV 150
Query: 589 SNFNSKQLERLLQHATV--KPVVNQVECHPYLNQKRLKEFCEARGVKITXYSPLGS 750
SNFN +QLE +L + KPV NQVECHPYLNQ +L +FC+++ + + +S LG+
Sbjct: 151 SNFNCRQLEMILNKPGLKYKPVCNQVECHPYLNQSKLLDFCKSKDIVLVAHSALGT 206
Score = 74.1 bits (174), Expect = 6e-13
Identities = 41/87 (47%), Positives = 50/87 (57%), Gaps = 3/87 (3%)
Frame = +3
Query: 150 PVFGXGXWXSKPGXVXXAV---KXAIDIGXRHIDCAYVYGNXXXVGXAITSKIKEGVVTR 320
PV G G + AV K AI+ G RHID AY+Y N VG AI SKI +G V R
Sbjct: 2 PVLGFGTYAPPEVPRNRAVEVTKLAIEAGFRHIDSAYLYNNEEQVGLAIRSKIADGSVKR 61
Query: 321 XXLFITSKLWNTFHRPDLVRGALQEXL 401
+F TSKLW TF +P +V+ AL+ L
Sbjct: 62 EDIFYTSKLWCTFFQPQMVQPALESSL 88
Score = 33.5 bits (73), Expect = 1.1
Identities = 14/38 (36%), Positives = 23/38 (60%)
Frame = +2
Query: 773 PDDPQXMEDPKLKXIADRLGKTVAQVLIRYQIDXGXIV 886
P+ P +EDP L +A + +T A + +RYQ+ G +V
Sbjct: 215 PNSPVLLEDPVLCALAKKHKRTPALIALRYQLQRGVVV 252
>D26125-1|BAA05122.1| 321|Homo sapiens 3
alpha-hydroxysteroid/dihydrodiol dehydrogenase DD4
protein.
Length = 321
Score = 122 bits (293), Expect = 2e-27
Identities = 56/116 (48%), Positives = 77/116 (66%), Gaps = 2/116 (1%)
Frame = +1
Query: 409 LNVQYLDLYLIHWPQAYKEDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGV 588
L + Y+DLYL+H+P A K + P D++GK+ F VD TW+ ME GL KSIGV
Sbjct: 104 LQLDYVDLYLLHFPMALKPGETPLPKDENGKVIFDTVDLSATWEVMEKCKDAGLAKSIGV 163
Query: 589 SNFNSKQLERLLQHATV--KPVVNQVECHPYLNQKRLKEFCEARGVKITXYSPLGS 750
SNFN +QLE +L + KPV NQVECHPYLNQ +L +FC+++ + + +S LG+
Sbjct: 164 SNFNCRQLEMILNKPGLKYKPVCNQVECHPYLNQSKLLDFCKSKDIVLVAHSALGT 219
Score = 75.4 bits (177), Expect = 3e-13
Identities = 44/101 (43%), Positives = 53/101 (52%), Gaps = 3/101 (2%)
Frame = +3
Query: 108 PXIPVVXFXXGASXPVFGXGXWXSKPGXVXXAV---KXAIDIGXRHIDCAYVYGNXXXVG 278
P V G PV G G + AV K AI+ G RHID AY+Y N VG
Sbjct: 1 PKYQRVELNDGHFMPVLGFGTYAPPEVPRNRAVEVTKLAIEAGFRHIDSAYLYNNEEQVG 60
Query: 279 XAITSKIKEGVVTRXXLFITSKLWNTFHRPDLVRGALQEXL 401
AI SKI +G V R +F TSKLW TF +P +V+ AL+ L
Sbjct: 61 LAIRSKIADGSVKREDIFYTSKLWCTFFQPQMVQPALESSL 101
Score = 33.5 bits (73), Expect = 1.1
Identities = 14/38 (36%), Positives = 23/38 (60%)
Frame = +2
Query: 773 PDDPQXMEDPKLKXIADRLGKTVAQVLIRYQIDXGXIV 886
P+ P +EDP L +A + +T A + +RYQ+ G +V
Sbjct: 228 PNSPVLLEDPVLCALAKKHKRTPALIALRYQLQRGVVV 265
>AL355303-2|CAI14202.1| 323|Homo sapiens aldo-keto reductase family
1, member C4 (chlordecone reductase; 3-alpha hydroxy
protein.
Length = 323
Score = 122 bits (293), Expect = 2e-27
Identities = 56/116 (48%), Positives = 77/116 (66%), Gaps = 2/116 (1%)
Frame = +1
Query: 409 LNVQYLDLYLIHWPQAYKEDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGV 588
L + Y+DLYL+H+P A K + P D++GK+ F VD TW+ ME GL KSIGV
Sbjct: 106 LQLDYVDLYLLHFPMALKPGETPLPKDENGKVIFDTVDLSATWEVMEKCKDAGLAKSIGV 165
Query: 589 SNFNSKQLERLLQHATV--KPVVNQVECHPYLNQKRLKEFCEARGVKITXYSPLGS 750
SNFN +QLE +L + KPV NQVECHPYLNQ +L +FC+++ + + +S LG+
Sbjct: 166 SNFNCRQLEMILNKPGLKYKPVCNQVECHPYLNQSKLLDFCKSKDIVLVAHSALGT 221
Score = 76.6 bits (180), Expect = 1e-13
Identities = 45/103 (43%), Positives = 54/103 (52%), Gaps = 3/103 (2%)
Frame = +3
Query: 102 MAPXIPVVXFXXGASXPVFGXGXWXSKPGXVXXAV---KXAIDIGXRHIDCAYVYGNXXX 272
M P V G PV G G + AV K AI+ G RHID AY+Y N
Sbjct: 1 MDPKYQRVELNDGHFMPVLGFGTYAPPEVPRNRAVEVTKLAIEAGFRHIDSAYLYNNEEQ 60
Query: 273 VGXAITSKIKEGVVTRXXLFITSKLWNTFHRPDLVRGALQEXL 401
VG AI SKI +G V R +F TSKLW TF +P +V+ AL+ L
Sbjct: 61 VGLAIRSKIADGSVKREDIFYTSKLWCTFFQPQMVQPALESSL 103
Score = 33.1 bits (72), Expect = 1.4
Identities = 14/38 (36%), Positives = 23/38 (60%)
Frame = +2
Query: 773 PDDPQXMEDPKLKXIADRLGKTVAQVLIRYQIDXGXIV 886
P+ P +EDP L +A + +T A + +RYQ+ G +V
Sbjct: 230 PNSPVLLEDPVLCALAKKHKQTPALIALRYQLQRGVVV 267
>AB032163-1|BAA92893.1| 323|Homo sapiens dihydrodiol dehydrogenase
4 protein.
Length = 323
Score = 122 bits (293), Expect = 2e-27
Identities = 56/116 (48%), Positives = 77/116 (66%), Gaps = 2/116 (1%)
Frame = +1
Query: 409 LNVQYLDLYLIHWPQAYKEDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGV 588
L + Y+DLYL+H+P A K + P D++GK+ F VD TW+ ME GL KSIGV
Sbjct: 106 LQLDYVDLYLLHFPMALKPGETPLPKDENGKVIFDTVDLSATWEVMEKCKDAGLAKSIGV 165
Query: 589 SNFNSKQLERLLQHATV--KPVVNQVECHPYLNQKRLKEFCEARGVKITXYSPLGS 750
SNFN +QLE +L + KPV NQVECHPYLNQ +L +FC+++ + + +S LG+
Sbjct: 166 SNFNCRQLEMILNKPGLKYKPVCNQVECHPYLNQSKLLDFCKSKDIVLVAHSALGT 221
Score = 76.6 bits (180), Expect = 1e-13
Identities = 45/103 (43%), Positives = 54/103 (52%), Gaps = 3/103 (2%)
Frame = +3
Query: 102 MAPXIPVVXFXXGASXPVFGXGXWXSKPGXVXXAV---KXAIDIGXRHIDCAYVYGNXXX 272
M P V G PV G G + AV K AI+ G RHID AY+Y N
Sbjct: 1 MDPKYQRVELNDGHFMPVLGFGTYAPPEVPRNRAVEVTKLAIEAGFRHIDSAYLYNNEEQ 60
Query: 273 VGXAITSKIKEGVVTRXXLFITSKLWNTFHRPDLVRGALQEXL 401
VG AI SKI +G V R +F TSKLW TF +P +V+ AL+ L
Sbjct: 61 VGLAIRSKIADGSVKREDIFYTSKLWCTFFQPQMVQPALESSL 103
Score = 33.5 bits (73), Expect = 1.1
Identities = 14/38 (36%), Positives = 23/38 (60%)
Frame = +2
Query: 773 PDDPQXMEDPKLKXIADRLGKTVAQVLIRYQIDXGXIV 886
P+ P +EDP L +A + +T A + +RYQ+ G +V
Sbjct: 230 PNSPVLLEDPVLCALAKKHKRTPALIALRYQLQRGVVV 267
>AB031085-1|BAA92885.1| 323|Homo sapiens dihydrodiol dehydrogenase
4 protein.
Length = 323
Score = 122 bits (293), Expect = 2e-27
Identities = 56/116 (48%), Positives = 77/116 (66%), Gaps = 2/116 (1%)
Frame = +1
Query: 409 LNVQYLDLYLIHWPQAYKEDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGV 588
L + Y+DLYL+H+P A K + P D++GK+ F VD TW+ ME GL KSIGV
Sbjct: 106 LQLDYVDLYLLHFPMALKPGETPLPKDENGKVIFDTVDLSATWEVMEKCKDAGLAKSIGV 165
Query: 589 SNFNSKQLERLLQHATV--KPVVNQVECHPYLNQKRLKEFCEARGVKITXYSPLGS 750
SNFN +QLE +L + KPV NQVECHPYLNQ +L +FC+++ + + +S LG+
Sbjct: 166 SNFNCRQLEMILNKPGLKYKPVCNQVECHPYLNQSKLLDFCKSKDIVLVAHSALGT 221
Score = 76.6 bits (180), Expect = 1e-13
Identities = 45/103 (43%), Positives = 54/103 (52%), Gaps = 3/103 (2%)
Frame = +3
Query: 102 MAPXIPVVXFXXGASXPVFGXGXWXSKPGXVXXAV---KXAIDIGXRHIDCAYVYGNXXX 272
M P V G PV G G + AV K AI+ G RHID AY+Y N
Sbjct: 1 MDPKYQRVELNDGHFMPVLGFGTYAPPEVPRNRAVEVTKLAIEAGFRHIDSAYLYNNEEQ 60
Query: 273 VGXAITSKIKEGVVTRXXLFITSKLWNTFHRPDLVRGALQEXL 401
VG AI SKI +G V R +F TSKLW TF +P +V+ AL+ L
Sbjct: 61 VGLAIRSKIADGSVKREDIFYTSKLWCTFFQPQMVQPALESSL 103
Score = 33.5 bits (73), Expect = 1.1
Identities = 14/38 (36%), Positives = 23/38 (60%)
Frame = +2
Query: 773 PDDPQXMEDPKLKXIADRLGKTVAQVLIRYQIDXGXIV 886
P+ P +EDP L +A + +T A + +RYQ+ G +V
Sbjct: 230 PNSPVLLEDPVLCALAKKHKRTPALIALRYQLQRGVVV 267
>BC020744-1|AAH20744.1| 323|Homo sapiens aldo-keto reductase family
1, member C4 (chlordecone reductase; 3-alpha hydroxy
protein.
Length = 323
Score = 121 bits (292), Expect = 3e-27
Identities = 56/116 (48%), Positives = 77/116 (66%), Gaps = 2/116 (1%)
Frame = +1
Query: 409 LNVQYLDLYLIHWPQAYKEDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGV 588
L + Y+DLYL+H+P A K + P D++GK+ F VD TW+ ME GL KSIGV
Sbjct: 106 LQLDYVDLYLLHFPMALKPGETPLPKDENGKVIFDTVDLSATWEVMEKCKDAGLAKSIGV 165
Query: 589 SNFNSKQLERLLQHATV--KPVVNQVECHPYLNQKRLKEFCEARGVKITXYSPLGS 750
SNFN +QLE +L + KPV NQVECHPYLNQ +L +FC+++ + + +S LG+
Sbjct: 166 SNFNYRQLEMILNKPGLKYKPVCNQVECHPYLNQSKLLDFCKSKDIVLVAHSALGT 221
Score = 76.6 bits (180), Expect = 1e-13
Identities = 45/103 (43%), Positives = 54/103 (52%), Gaps = 3/103 (2%)
Frame = +3
Query: 102 MAPXIPVVXFXXGASXPVFGXGXWXSKPGXVXXAV---KXAIDIGXRHIDCAYVYGNXXX 272
M P V G PV G G + AV K AI+ G RHID AY+Y N
Sbjct: 1 MDPKYQRVELNDGHFMPVLGFGTYAPPEVPRNRAVEVTKLAIEAGFRHIDSAYLYNNEEQ 60
Query: 273 VGXAITSKIKEGVVTRXXLFITSKLWNTFHRPDLVRGALQEXL 401
VG AI SKI +G V R +F TSKLW TF +P +V+ AL+ L
Sbjct: 61 VGLAIRSKIADGSVKREDIFYTSKLWCTFFQPQMVQPALESSL 103
Score = 33.5 bits (73), Expect = 1.1
Identities = 14/38 (36%), Positives = 23/38 (60%)
Frame = +2
Query: 773 PDDPQXMEDPKLKXIADRLGKTVAQVLIRYQIDXGXIV 886
P+ P +EDP L +A + +T A + +RYQ+ G +V
Sbjct: 230 PNSPVLLEDPVLCALAKKHKRTPALIALRYQLQRGVVV 267
>AK058142-1|BAB71682.1| 146|Homo sapiens protein ( Homo sapiens
cDNA FLJ25413 fis, clone TST03402, highly similar to
3-OXO-5-BETA-STEROID 4-DEHYDROGENASE (EC 1.3.99.6). ).
Length = 146
Score = 105 bits (251), Expect = 3e-22
Identities = 51/112 (45%), Positives = 69/112 (61%), Gaps = 3/112 (2%)
Frame = +1
Query: 454 AYKEDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQHA 633
A+K ++P D++GK + + TW+AME GLVKS+GVSNFN +QLE +L
Sbjct: 2 AFKPGDEIYPRDENGKWLYHKSNLCATWEAMEACKDAGLVKSLGVSNFNRRQLELILNKP 61
Query: 634 TV--KPVVNQVECHPYLNQKRLKEFCEARGVKITXYSPLGSPDRP-WGQARR 780
+ KPV NQVECHPY Q +L +FC+ + IT YSPLG+ P W Q +
Sbjct: 62 GLKHKPVSNQVECHPYFTQPKLLKFCQQHDIVITAYSPLGTSRNPIWRQLHK 113
>AL355480-2|CAI22458.1| 147|Homo sapiens aldo-keto reductase family
1, member A1 (aldehydela) protein.
Length = 147
Score = 93.5 bits (222), Expect = 9e-19
Identities = 44/94 (46%), Positives = 56/94 (59%), Gaps = 1/94 (1%)
Frame = +3
Query: 123 VXFXXGASXPVFGXGXWXSKPGXVXXAVKXAIDIGXRHIDCAYVYGNXXXVGXAITSKIK 302
V G P+ G G W S+PG V AVK A+ +G RHIDCA +YGN +G A+ +
Sbjct: 6 VLLHTGQKMPLIGLGTWKSEPGQVKAAVKYALSVGYRHIDCAAIYGNEPEIGEALKEDVG 65
Query: 303 EG-VVTRXXLFITSKLWNTFHRPDLVRGALQEXL 401
G V R LF+TSKLWNT H P+ V AL++ L
Sbjct: 66 PGKAVPREELFVTSKLWNTKHHPEDVEPALRKTL 99
Score = 54.0 bits (124), Expect = 7e-07
Identities = 20/47 (42%), Positives = 31/47 (65%)
Frame = +1
Query: 406 NLNVQYLDLYLIHWPQAYKEDGSLFPTDQSGKIQFSDVDYVDTWKAM 546
+L ++YLDLYL+HWP A++ + FP + G I + Y +TWKA+
Sbjct: 101 DLQLEYLDLYLMHWPYAFERGDNPFPKNADGTICYDSTHYKETWKAL 147
>AB040822-1|BAC54567.1| 222|Homo sapiens aldo-keto reductase
related protein 3 protein.
Length = 222
Score = 89.0 bits (211), Expect = 2e-17
Identities = 43/84 (51%), Positives = 48/84 (57%)
Frame = +3
Query: 150 PVFGXGXWXSKPGXVXXAVKXAIDIGXRHIDCAYVYGNXXXVGXAITSKIKEGVVTRXXL 329
P G W + PG V AVK AID G RH DCAY Y N VG I KIKEG V R L
Sbjct: 5 PAVGLSSWKASPGKVTEAVKEAIDAGYRHFDCAYFYHNEREVGAGIRCKIKEGAVRREDL 64
Query: 330 FITSKLWNTFHRPDLVRGALQEXL 401
FI +KLW T H+ LV A ++ L
Sbjct: 65 FIATKLWCTCHKKSLVETACRKSL 88
Score = 38.3 bits (85), Expect = 0.038
Identities = 24/72 (33%), Positives = 32/72 (44%), Gaps = 19/72 (26%)
Frame = +1
Query: 388 CRXPWXNLNVQYLDLYLIHWPQAYKED--------GSL-----------FPTDQSGKIQF 510
CR L + YLDLYLIHWP +K L P D+S +
Sbjct: 84 CRKSLKALKLNYLDLYLIHWPMGFKPPHPEWIMSCSELSFCLSHPRVQDLPLDESNMVIP 143
Query: 511 SDVDYVDTWKAM 546
SD D++DTW+ +
Sbjct: 144 SDTDFLDTWEIL 155
>AB040821-1|BAC54566.1| 263|Homo sapiens aldo-keto reductase
related protein 2 protein.
Length = 263
Score = 89.0 bits (211), Expect = 2e-17
Identities = 43/84 (51%), Positives = 48/84 (57%)
Frame = +3
Query: 150 PVFGXGXWXSKPGXVXXAVKXAIDIGXRHIDCAYVYGNXXXVGXAITSKIKEGVVTRXXL 329
P G W + PG V AVK AID G RH DCAY Y N VG I KIKEG V R L
Sbjct: 5 PAVGLSSWKASPGKVTEAVKEAIDAGYRHFDCAYFYHNEREVGAGIRCKIKEGAVRREDL 64
Query: 330 FITSKLWNTFHRPDLVRGALQEXL 401
FI +KLW T H+ LV A ++ L
Sbjct: 65 FIATKLWCTCHKKSLVETACRKSL 88
Score = 82.6 bits (195), Expect = 2e-15
Identities = 49/112 (43%), Positives = 62/112 (55%), Gaps = 21/112 (18%)
Frame = +1
Query: 388 CRXPWXNLNVQYLDLYLIHWPQAYKEDGSLF-------------------PTDQSGKIQF 510
CR L + YLDLYLIHWP +K + P D+S +
Sbjct: 84 CRKSLKALKLNYLDLYLIHWPMGFKPPHPEWIMSCSELSFCLSHPRVQDLPLDESNMVIP 143
Query: 511 SDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQHATV--KPVVNQV 660
SD D++DTW+AME LV GLVK+IGVSNFN +QLERLL + KP+ NQ+
Sbjct: 144 SDTDFLDTWEAMEDLVITGLVKNIGVSNFNHEQLERLLNKPGLRFKPLTNQI 195
>AB040820-1|BAC54565.1| 250|Homo sapiens aldo-keto reductase
related protein 1 protein.
Length = 250
Score = 89.0 bits (211), Expect = 2e-17
Identities = 43/84 (51%), Positives = 48/84 (57%)
Frame = +3
Query: 150 PVFGXGXWXSKPGXVXXAVKXAIDIGXRHIDCAYVYGNXXXVGXAITSKIKEGVVTRXXL 329
P G W + PG V AVK AID G RH DCAY Y N VG I KIKEG V R L
Sbjct: 5 PAVGLSSWKASPGKVTEAVKEAIDAGYRHFDCAYFYHNEREVGAGIRCKIKEGAVRREDL 64
Query: 330 FITSKLWNTFHRPDLVRGALQEXL 401
FI +KLW T H+ LV A ++ L
Sbjct: 65 FIATKLWCTCHKKSLVETACRKSL 88
Score = 82.6 bits (195), Expect = 2e-15
Identities = 49/112 (43%), Positives = 62/112 (55%), Gaps = 21/112 (18%)
Frame = +1
Query: 388 CRXPWXNLNVQYLDLYLIHWPQAYKEDGSLF-------------------PTDQSGKIQF 510
CR L + YLDLYLIHWP +K + P D+S +
Sbjct: 84 CRKSLKALKLNYLDLYLIHWPMGFKPPHPEWIMSCSELSFCLSHPRVQDLPLDESNMVIP 143
Query: 511 SDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQHATV--KPVVNQV 660
SD D++DTW+AME LV GLVK+IGVSNFN +QLERLL + KP+ NQ+
Sbjct: 144 SDTDFLDTWEAMEDLVITGLVKNIGVSNFNHEQLERLLNKPGLRFKPLTNQI 195
>BC101205-1|AAI01206.1| 129|Homo sapiens aldo-keto reductase family
1, member C-like 1 protein.
Length = 129
Score = 75.8 bits (178), Expect = 2e-13
Identities = 42/96 (43%), Positives = 50/96 (52%), Gaps = 3/96 (3%)
Frame = +3
Query: 123 VXFXXGASXPVFGXGXWX---SKPGXVXXAVKXAIDIGXRHIDCAYVYGNXXXVGXAITS 293
V G PV G G + + A K AID+G RHID AY+Y N VG AI
Sbjct: 11 VRLNDGPFMPVLGFGTYAPDHTPKSQAAEATKVAIDVGFRHIDSAYLYQNEEEVGQAIWE 70
Query: 294 KIKEGVVTRXXLFITSKLWNTFHRPDLVRGALQEXL 401
KI +G V R +F T KLW TF R +LV AL+ L
Sbjct: 71 KIADGTVKREEIFYTIKLWATFFRAELVHPALERSL 106
>BC101204-1|AAI01205.1| 129|Homo sapiens aldo-keto reductase family
1, member C-like 1 protein.
Length = 129
Score = 75.8 bits (178), Expect = 2e-13
Identities = 42/96 (43%), Positives = 50/96 (52%), Gaps = 3/96 (3%)
Frame = +3
Query: 123 VXFXXGASXPVFGXGXWX---SKPGXVXXAVKXAIDIGXRHIDCAYVYGNXXXVGXAITS 293
V G PV G G + + A K AID+G RHID AY+Y N VG AI
Sbjct: 11 VRLNDGPFMPVLGFGTYAPDHTPKSQAAEATKVAIDVGFRHIDSAYLYQNEEEVGQAIWE 70
Query: 294 KIKEGVVTRXXLFITSKLWNTFHRPDLVRGALQEXL 401
KI +G V R +F T KLW TF R +LV AL+ L
Sbjct: 71 KIADGTVKREEIFYTIKLWATFFRAELVHPALERSL 106
>AL391427-2|CAI14727.1| 302|Homo sapiens aldo-keto reductase family
1, member C-like 1 protein.
Length = 302
Score = 75.8 bits (178), Expect = 2e-13
Identities = 42/96 (43%), Positives = 50/96 (52%), Gaps = 3/96 (3%)
Frame = +3
Query: 123 VXFXXGASXPVFGXGXWX---SKPGXVXXAVKXAIDIGXRHIDCAYVYGNXXXVGXAITS 293
V G PV G G + + A K AID+G RHID AY+Y N VG AI
Sbjct: 11 VRLNDGPFMPVLGFGTYAPDHTPKSQAAEATKVAIDVGFRHIDSAYLYQNEEEVGQAIWE 70
Query: 294 KIKEGVVTRXXLFITSKLWNTFHRPDLVRGALQEXL 401
KI +G V R +F T KLW TF R +LV AL+ L
Sbjct: 71 KIADGTVKREEIFYTIKLWATFFRAELVHPALERSL 106
Score = 72.1 bits (169), Expect = 2e-12
Identities = 47/120 (39%), Positives = 60/120 (50%), Gaps = 2/120 (1%)
Frame = +1
Query: 409 LNVQYLDLYLIHWPQAYKEDGS-LFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIG 585
L Y+DL++IH P A K+ G L P D SG+I V+ DTW+ L K GL
Sbjct: 109 LGPDYVDLFIIHVPFAMKQPGKELLPKDASGEIILETVELCDTWELELILNKPGL----- 163
Query: 586 VSNFNSKQLERLLQHATVKPVVNQV-ECHPYLNQKRLKEFCEARGVKITXYSPLGSPDRP 762
KP NQV ECHPYLNQ +L EFC+++ + + YS LGS P
Sbjct: 164 ----------------RYKPTCNQVVECHPYLNQSKLLEFCKSKDIVLVAYSALGSQRDP 207
Score = 38.3 bits (85), Expect = 0.038
Identities = 17/47 (36%), Positives = 27/47 (57%)
Frame = +2
Query: 746 ARRTDPGAKPDDPQXMEDPKLKXIADRLGKTVAQVLIRYQIDXGXIV 886
++R PD P +E+P LK IA + ++ QV +RYQ+ G +V
Sbjct: 203 SQRDPQWVDPDCPHLLEEPILKSIAKKHSRSPGQVALRYQLQRGVVV 249
>AL355303-1|CAI14201.1| 302|Homo sapiens aldo-keto reductase family
1, member C-like 1 protein.
Length = 302
Score = 75.8 bits (178), Expect = 2e-13
Identities = 42/96 (43%), Positives = 50/96 (52%), Gaps = 3/96 (3%)
Frame = +3
Query: 123 VXFXXGASXPVFGXGXWX---SKPGXVXXAVKXAIDIGXRHIDCAYVYGNXXXVGXAITS 293
V G PV G G + + A K AID+G RHID AY+Y N VG AI
Sbjct: 11 VRLNDGPFMPVLGFGTYAPDHTPKSQAAEATKVAIDVGFRHIDSAYLYQNEEEVGQAIWE 70
Query: 294 KIKEGVVTRXXLFITSKLWNTFHRPDLVRGALQEXL 401
KI +G V R +F T KLW TF R +LV AL+ L
Sbjct: 71 KIADGTVKREEIFYTIKLWATFFRAELVHPALERSL 106
Score = 72.1 bits (169), Expect = 2e-12
Identities = 47/120 (39%), Positives = 60/120 (50%), Gaps = 2/120 (1%)
Frame = +1
Query: 409 LNVQYLDLYLIHWPQAYKEDGS-LFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIG 585
L Y+DL++IH P A K+ G L P D SG+I V+ DTW+ L K GL
Sbjct: 109 LGPDYVDLFIIHVPFAMKQPGKELLPKDASGEIILETVELCDTWELELILNKPGL----- 163
Query: 586 VSNFNSKQLERLLQHATVKPVVNQV-ECHPYLNQKRLKEFCEARGVKITXYSPLGSPDRP 762
KP NQV ECHPYLNQ +L EFC+++ + + YS LGS P
Sbjct: 164 ----------------RYKPTCNQVVECHPYLNQSKLLEFCKSKDIVLVAYSALGSQRDP 207
Score = 38.3 bits (85), Expect = 0.038
Identities = 17/47 (36%), Positives = 27/47 (57%)
Frame = +2
Query: 746 ARRTDPGAKPDDPQXMEDPKLKXIADRLGKTVAQVLIRYQIDXGXIV 886
++R PD P +E+P LK IA + ++ QV +RYQ+ G +V
Sbjct: 203 SQRDPQWVDPDCPHLLEEPILKSIAKKHSRSPGQVALRYQLQRGVVV 249
>AK131335-1|BAD18494.1| 129|Homo sapiens protein ( Homo sapiens
cDNA FLJ16347 fis, clone TESTI2036288, moderately
similar to PROSTAGLANDIN-F SYNTHASE 1 (EC 1.1.1.188). ).
Length = 129
Score = 75.8 bits (178), Expect = 2e-13
Identities = 42/96 (43%), Positives = 50/96 (52%), Gaps = 3/96 (3%)
Frame = +3
Query: 123 VXFXXGASXPVFGXGXWX---SKPGXVXXAVKXAIDIGXRHIDCAYVYGNXXXVGXAITS 293
V G PV G G + + A K AID+G RHID AY+Y N VG AI
Sbjct: 11 VRLNDGPFMPVLGFGTYAPDHTPKSQAAEATKVAIDVGFRHIDSAYLYQNEEEVGQAIWE 70
Query: 294 KIKEGVVTRXXLFITSKLWNTFHRPDLVRGALQEXL 401
KI +G V R +F T KLW TF R +LV AL+ L
Sbjct: 71 KIADGTVKREEIFYTIKLWATFFRAELVHPALERSL 106
>AB037902-1|BAA92887.1| 130|Homo sapiens truncated aldo-keto
reductase protein.
Length = 130
Score = 75.4 bits (177), Expect = 3e-13
Identities = 40/104 (38%), Positives = 56/104 (53%), Gaps = 3/104 (2%)
Frame = +3
Query: 123 VXFXXGASXPVFGXGXWXSKP---GXVXXAVKXAIDIGXRHIDCAYVYGNXXXVGXAITS 293
V G P+ G G ++ V AV+ AID+G RHID AY + N +G AI
Sbjct: 9 VKLNDGKFMPILGFGTSVARKVAMSNVEEAVQVAIDVGYRHIDSAYTHLNEEGIGQAIRK 68
Query: 294 KIKEGVVTRXXLFITSKLWNTFHRPDLVRGALQEXLXQSERSVL 425
KI G V R +F T+K+W TF RP+LV+ L+ L + + S +
Sbjct: 69 KIANGTVKRKDIFYTTKVWGTFSRPELVQRGLEMSLKKLQLSYM 112
>AB028065-1|BAA88489.1| 67|Homo sapiens prostaglandin F synthase
protein.
Length = 67
Score = 66.1 bits (154), Expect = 2e-10
Identities = 34/63 (53%), Positives = 41/63 (65%), Gaps = 2/63 (3%)
Frame = +1
Query: 475 LFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQHATV--KPV 648
L PTD++GK+ F VD TW+AME GL KSIGVSNFN +QLE +L + KPV
Sbjct: 5 LSPTDENGKVIFDIVDLCTTWEAMEKCKDAGLAKSIGVSNFNRRQLEMILNKPGLKYKPV 64
Query: 649 VNQ 657
NQ
Sbjct: 65 CNQ 67
>L35546-1|AAA65028.1| 274|Homo sapiens gamma-glutamylcysteine
synthetase light subunit protein.
Length = 274
Score = 39.5 bits (88), Expect = 0.016
Identities = 19/42 (45%), Positives = 27/42 (64%)
Frame = +1
Query: 535 WKAMEPLVKEGLVKSIGVSNFNSKQLERLLQHATVKPVVNQV 660
W+ +E LV+ + +IG S+ + QLE+L Q A VKP NQV
Sbjct: 147 WEELENLVQSKKIVAIGTSDLDKTQLEQLYQWAQVKPNSNQV 188
>CR541833-1|CAG46632.1| 274|Homo sapiens GCLM protein.
Length = 274
Score = 39.5 bits (88), Expect = 0.016
Identities = 19/42 (45%), Positives = 27/42 (64%)
Frame = +1
Query: 535 WKAMEPLVKEGLVKSIGVSNFNSKQLERLLQHATVKPVVNQV 660
W+ +E LV+ + +IG S+ + QLE+L Q A VKP NQV
Sbjct: 147 WEELENLVQSKKIVAIGTSDLDKTQLEQLYQWAQVKPNSNQV 188
>BC041809-1|AAH41809.1| 274|Homo sapiens glutamate-cysteine ligase,
modifier subunit protein.
Length = 274
Score = 39.5 bits (88), Expect = 0.016
Identities = 19/42 (45%), Positives = 27/42 (64%)
Frame = +1
Query: 535 WKAMEPLVKEGLVKSIGVSNFNSKQLERLLQHATVKPVVNQV 660
W+ +E LV+ + +IG S+ + QLE+L Q A VKP NQV
Sbjct: 147 WEELENLVQSKKIVAIGTSDLDKTQLEQLYQWAQVKPNSNQV 188
>AY773965-1|AAV28733.1| 274|Homo sapiens glutamate-cysteine ligase,
modifier subunit protein.
Length = 274
Score = 39.5 bits (88), Expect = 0.016
Identities = 19/42 (45%), Positives = 27/42 (64%)
Frame = +1
Query: 535 WKAMEPLVKEGLVKSIGVSNFNSKQLERLLQHATVKPVVNQV 660
W+ +E LV+ + +IG S+ + QLE+L Q A VKP NQV
Sbjct: 147 WEELENLVQSKKIVAIGTSDLDKTQLEQLYQWAQVKPNSNQV 188
>AL117351-10|CAI22976.1| 274|Homo sapiens glutamate-cysteine
ligase, modifier subunit protein.
Length = 274
Score = 39.5 bits (88), Expect = 0.016
Identities = 19/42 (45%), Positives = 27/42 (64%)
Frame = +1
Query: 535 WKAMEPLVKEGLVKSIGVSNFNSKQLERLLQHATVKPVVNQV 660
W+ +E LV+ + +IG S+ + QLE+L Q A VKP NQV
Sbjct: 147 WEELENLVQSKKIVAIGTSDLDKTQLEQLYQWAQVKPNSNQV 188
>AL049796-2|CAI21813.1| 274|Homo sapiens glutamate-cysteine ligase,
modifier subunit protein.
Length = 274
Score = 39.5 bits (88), Expect = 0.016
Identities = 19/42 (45%), Positives = 27/42 (64%)
Frame = +1
Query: 535 WKAMEPLVKEGLVKSIGVSNFNSKQLERLLQHATVKPVVNQV 660
W+ +E LV+ + +IG S+ + QLE+L Q A VKP NQV
Sbjct: 147 WEELENLVQSKKIVAIGTSDLDKTQLEQLYQWAQVKPNSNQV 188
>BC030254-1|AAH30254.1| 433|Homo sapiens chromosome 20 open reading
frame 160 protein.
Length = 433
Score = 35.1 bits (77), Expect = 0.35
Identities = 23/68 (33%), Positives = 34/68 (50%), Gaps = 1/68 (1%)
Frame = +2
Query: 425 WICT*YTGPRPTRKTALSSRPTNQVKSSSRTSITWTPGRLWSRSSKRV-WSRASESPTST 601
W+C+ PR K ++RP + S + T+ T +W+ SS R+ WSR S +
Sbjct: 352 WLCSRIMAPRTPLKHVTAARP--HLLSMAPTAAAATTA-VWAWSSYRITWSRCGVSWGPS 408
Query: 602 RSSWRGCC 625
RSS CC
Sbjct: 409 RSSSLRCC 416
>AL031658-5|CAI42581.1| 433|Homo sapiens chromosome 20 open reading
frame 160 protein.
Length = 433
Score = 35.1 bits (77), Expect = 0.35
Identities = 23/68 (33%), Positives = 34/68 (50%), Gaps = 1/68 (1%)
Frame = +2
Query: 425 WICT*YTGPRPTRKTALSSRPTNQVKSSSRTSITWTPGRLWSRSSKRV-WSRASESPTST 601
W+C+ PR K ++RP + S + T+ T +W+ SS R+ WSR S +
Sbjct: 352 WLCSRIMAPRTPLKHVTAARP--HLLSMAPTAAAATTA-VWAWSSYRITWSRCGVSWGPS 408
Query: 602 RSSWRGCC 625
RSS CC
Sbjct: 409 RSSSLRCC 416
>AF044961-1|AAC15671.1| 85|Homo sapiens aldose reductase-related
protein protein.
Length = 85
Score = 35.1 bits (77), Expect = 0.35
Identities = 17/32 (53%), Positives = 21/32 (65%)
Frame = +2
Query: 800 PKLKXIADRLGKTVAQVLIRYQIDXGXIVXPE 895
PK+K IA + KT AQVLIR+ I IV P+
Sbjct: 1 PKIKEIAAKHKKTAAQVLIRFHIQRNVIVIPK 32
>AB058756-1|BAB47482.1| 708|Homo sapiens KIAA1853 protein protein.
Length = 708
Score = 33.5 bits (73), Expect = 1.1
Identities = 27/73 (36%), Positives = 35/73 (47%)
Frame = +2
Query: 440 YTGPRPTRKTALSSRPTNQVKSSSRTSITWTPGRLWSRSSKRVWSRASESPTSTRSSWRG 619
Y P P+ +LSS + SSSR S + + R WSRS R SR S +S+ S
Sbjct: 616 YYRPSPSSSGSLSSTSSWYSSSSSR-SASRSYSRSWSRSRSRRRSRTRTSSSSSSRSPSP 674
Query: 620 CCSTRLSSRSSIR 658
+R SRS R
Sbjct: 675 GSRSRSRSRSRSR 687
>EF471359-1|ABO86192.1| 270|Homo sapiens MHC class I antigen
protein.
Length = 270
Score = 32.3 bits (70), Expect = 2.5
Identities = 22/75 (29%), Positives = 32/75 (42%)
Frame = +2
Query: 464 KTALSSRPTNQVKSSSRTSITWTPGRLWSRSSKRVWSRASESPTSTRSSWRGCCSTRLSS 643
KT ++ P + +++ R W G + W R E T TRSSWR S
Sbjct: 185 KTHMTHHPISDHEATLRC---WALG-FYPAEITLTWQRDGEDQTHTRSSWRPGLQGMEPS 240
Query: 644 RSSIRWNVILTSTRN 688
RS W +L +R+
Sbjct: 241 RSGRLWWCLLERSRD 255
>U30826-1|AAA93070.1| 272|Homo sapiens SRp40-1 protein.
Length = 272
Score = 30.7 bits (66), Expect = 7.5
Identities = 26/69 (37%), Positives = 37/69 (53%), Gaps = 1/69 (1%)
Frame = +2
Query: 452 RPTRKTALSSRPTNQVKSSSRTSITWTPGRLWSRSSKRVWSRA-SESPTSTRSSWRGCCS 628
R +T SSR ++ +S SR S ++ R SRS R SR+ S SP +S RG S
Sbjct: 189 RSRSRTRSSSRSRSRSRSRSRKS--YSRSRSRSRSRSRSKSRSVSRSPVPEKSQKRG-SS 245
Query: 629 TRLSSRSSI 655
+R S +S+
Sbjct: 246 SRSKSPASV 254
>BT007089-1|AAP35752.1| 272|Homo sapiens splicing factor,
arginine/serine-rich 5 protein.
Length = 272
Score = 30.7 bits (66), Expect = 7.5
Identities = 26/69 (37%), Positives = 37/69 (53%), Gaps = 1/69 (1%)
Frame = +2
Query: 452 RPTRKTALSSRPTNQVKSSSRTSITWTPGRLWSRSSKRVWSRA-SESPTSTRSSWRGCCS 628
R +T SSR ++ +S SR S ++ R SRS R SR+ S SP +S RG S
Sbjct: 189 RSRSRTRSSSRSRSRSRSRSRKS--YSRSRSRSRSRSRSKSRSVSRSPVPEKSQKRG-SS 245
Query: 629 TRLSSRSSI 655
+R S +S+
Sbjct: 246 SRSKSPASV 254
>BC040209-1|AAH40209.1| 272|Homo sapiens splicing factor,
arginine/serine-rich 5 protein.
Length = 272
Score = 30.7 bits (66), Expect = 7.5
Identities = 26/69 (37%), Positives = 37/69 (53%), Gaps = 1/69 (1%)
Frame = +2
Query: 452 RPTRKTALSSRPTNQVKSSSRTSITWTPGRLWSRSSKRVWSRA-SESPTSTRSSWRGCCS 628
R +T SSR ++ +S SR S ++ R SRS R SR+ S SP +S RG S
Sbjct: 189 RSRSRTRSSSRSRSRSRSRSRKS--YSRSRSRSRSRSRSKSRSVSRSPVPEKSQKRG-SS 245
Query: 629 TRLSSRSSI 655
+R S +S+
Sbjct: 246 SRSKSPASV 254
>BC018823-1|AAH18823.1| 272|Homo sapiens splicing factor,
arginine/serine-rich 5 protein.
Length = 272
Score = 30.7 bits (66), Expect = 7.5
Identities = 26/69 (37%), Positives = 37/69 (53%), Gaps = 1/69 (1%)
Frame = +2
Query: 452 RPTRKTALSSRPTNQVKSSSRTSITWTPGRLWSRSSKRVWSRA-SESPTSTRSSWRGCCS 628
R +T SSR ++ +S SR S ++ R SRS R SR+ S SP +S RG S
Sbjct: 189 RSRSRTRSSSRSRSRSRSRSRKS--YSRSRSRSRSRSRSKSRSVSRSPVPEKSQKRG-SS 245
Query: 629 TRLSSRSSI 655
+R S +S+
Sbjct: 246 SRSKSPASV 254
>AY130006-1|AAN05090.1| 90|Homo sapiens MU-MB-2.76 protein.
Length = 90
Score = 30.7 bits (66), Expect = 7.5
Identities = 25/71 (35%), Positives = 36/71 (50%), Gaps = 1/71 (1%)
Frame = +2
Query: 449 PRPTRKTALSSRPTNQVKSSSRT-SITWTPGRLWSRSSKRVWSRASESPTSTRSSWRGCC 625
P P+ +LSS + SSSR+ S +++ R SRS +R +R S S +S S
Sbjct: 1 PSPSSSGSLSSTSSWYSSSSSRSASRSYSRSRSRSRSRRRSRTRTSSSSSSRSPSPGSRS 60
Query: 626 STRLSSRSSIR 658
+R SRS R
Sbjct: 61 RSRSRSRSRSR 71
>AB209804-1|BAD93041.1| 326|Homo sapiens CS0DF038YO05 variant
protein.
Length = 326
Score = 30.7 bits (66), Expect = 7.5
Identities = 26/69 (37%), Positives = 37/69 (53%), Gaps = 1/69 (1%)
Frame = +2
Query: 452 RPTRKTALSSRPTNQVKSSSRTSITWTPGRLWSRSSKRVWSRA-SESPTSTRSSWRGCCS 628
R +T SSR ++ +S SR S ++ R SRS R SR+ S SP +S RG S
Sbjct: 243 RSRSRTRSSSRSRSRSRSRSRKS--YSRSRSRSRSRSRSKSRSVSRSPVPEKSQKRG-SS 299
Query: 629 TRLSSRSSI 655
+R S +S+
Sbjct: 300 SRSKSPASV 308
>AL162417-13|CAI13418.1| 294|Homo sapiens globoside
alpha-1,3-N-acetylgalactosaminyltransferase 1 protein.
Length = 294
Score = 30.3 bits (65), Expect = 10.0
Identities = 17/53 (32%), Positives = 27/53 (50%), Gaps = 1/53 (1%)
Frame = +2
Query: 419 STWICT*YTGPRPTRKTALSSR-PTNQVKSSSRTSITWTPGRLWSRSSKRVWS 574
S W+ T ++ P P+R T R P + S+ T + GR W+ SS +W+
Sbjct: 151 SRWVPTGFSAPSPSRVTPTGRRHPCAGWRPSASTLLRGLTGR-WTTSSALMWT 202
>AK074639-1|BAC11106.1| 294|Homo sapiens 40). protein.
Length = 294
Score = 30.3 bits (65), Expect = 10.0
Identities = 17/53 (32%), Positives = 27/53 (50%), Gaps = 1/53 (1%)
Frame = +2
Query: 419 STWICT*YTGPRPTRKTALSSR-PTNQVKSSSRTSITWTPGRLWSRSSKRVWS 574
S W+ T ++ P P+R T R P + S+ T + GR W+ SS +W+
Sbjct: 151 SRWVPTGFSAPSPSRVTPTGRRHPCAGWRPSASTLLRGLTGR-WTTSSALMWT 202
>AF117899-1|AAF27280.1| 363|Homo sapiens LDLR-FUT fusion protein
protein.
Length = 363
Score = 30.3 bits (65), Expect = 10.0
Identities = 23/61 (37%), Positives = 29/61 (47%)
Frame = +3
Query: 411 ERSVLGSVPDTLAPGLQGRRLSLPDRPIR*NPVLGRRLRGHLEGYGAARQRGSGQEHRSL 590
ER++ P APG G RLS P PV R EG G +RG G+E RS+
Sbjct: 243 ERTLRKGRPHPAAPGTPGVRLSGPAALPSAQPV-----RTGSEGLGRRGRRGRGRESRSV 297
Query: 591 Q 593
+
Sbjct: 298 R 298
Database: human
Posted date: Oct 23, 2007 1:18 PM
Number of letters in database: 76,859,062
Number of sequences in database: 237,096
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 116,576,337
Number of Sequences: 237096
Number of extensions: 2359139
Number of successful extensions: 7967
Number of sequences better than 10.0: 112
Number of HSP's better than 10.0 without gapping: 6923
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 7833
length of database: 76,859,062
effective HSP length: 90
effective length of database: 55,520,422
effective search space used: 11603768198
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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