Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= MFBP02_F_N24
(898 letters)
Database: human
237,096 sequences; 76,859,062 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
D90228-1|BAA14278.1| 427|Homo sapiens mitochondrial acetoacetyl... 255 1e-67
D10511-1|BAA01387.1| 427|Homo sapiens mitochondrial acetoacetyl... 255 1e-67
AL135914-6|CAI21850.1| 397|Homo sapiens acetyl-Coenzyme A acety... 144 5e-34
AF356877-1|AAM00223.1| 397|Homo sapiens acetyl CoA transferase-... 144 5e-34
BC000408-1|AAH00408.1| 397|Homo sapiens ACAT2 protein protein. 143 7e-34
AB208993-1|BAD92230.1| 404|Homo sapiens Acetyl-CoA acetyltransf... 143 7e-34
S70154-1|AAB30856.1| 397|Homo sapiens cytosolic acetoacetyl-coe... 143 9e-34
BC010942-1|AAH10942.1| 162|Homo sapiens ACAT1 protein protein. 120 7e-27
BC063853-1|AAH63853.1| 289|Homo sapiens ACAT1 protein protein. 118 2e-26
BC001918-1|AAH01918.1| 397|Homo sapiens acetyl-Coenzyme A acylt... 96 2e-19
D16294-1|BAA03800.1| 397|Homo sapiens mitochondrial 3-oxoacyl-C... 94 5e-19
X65140-1|CAA46270.1| 424|Homo sapiens peroxisomal 3-oxoacyl-CoA... 71 4e-12
X14813-1|CAA32918.1| 424|Homo sapiens protein ( Human liver mRN... 71 4e-12
X12966-1|CAA31412.1| 424|Homo sapiens protein ( Human mRNA for ... 71 4e-12
BC011977-1|AAH11977.1| 424|Homo sapiens acetyl-Coenzyme A acylt... 71 4e-12
BC000635-1|AAH00635.1| 424|Homo sapiens acetyl-Coenzyme A acylt... 71 4e-12
BC014572-1|AAH14572.1| 475|Homo sapiens hydroxyacyl-Coenzyme A ... 66 1e-10
D16481-1|BAA03942.1| 474|Homo sapiens 3-ketoacyl-CoA thiolase b... 66 2e-10
BC066963-1|AAH66963.1| 475|Homo sapiens hydroxyacyl-Coenzyme A ... 66 2e-10
BC030824-1|AAH30824.1| 475|Homo sapiens hydroxyacyl-Coenzyme A ... 66 2e-10
BC017564-1|AAH17564.1| 475|Homo sapiens hydroxyacyl-Coenzyme A ... 66 2e-10
AC010896-2|AAY14644.1| 474|Homo sapiens unknown protein. 66 2e-10
BC014474-1|AAH14474.1| 331|Homo sapiens ACAA1 protein protein. 54 7e-10
X51460-1|CAA35825.1| 326|Homo sapiens 3-oxoacyl-CoA thiolase pr... 58 4e-08
U49441-1|AAB09424.1| 224|Homo sapiens mitochondrial trifunction... 48 5e-05
D86850-1|BAA22061.1| 410|Homo sapiens 3-ketoacyl-CoA thiolase b... 46 1e-04
AF035295-1|AAB88181.1| 132|Homo sapiens protein ( Homo sapiens ... 41 0.007
>D90228-1|BAA14278.1| 427|Homo sapiens mitochondrial
acetoacetyl-CoA thiolase precursor protein.
Length = 427
Score = 255 bits (625), Expect = 1e-67
Identities = 126/230 (54%), Positives = 157/230 (68%)
Frame = +3
Query: 174 AFSTKVSLNEVVIASAVRTPMXXXXXXXXXXXXXXXXXXXVNAAIERAGIPKEEIKEVYI 353
++ +K +L EVVI SA RTP+ + AIE+AGIPKEE+KE Y+
Sbjct: 32 SYVSKPTLKEVVIVSATRTPIGSFLGSLSLLPATKLGSIAIQGAIEKAGIPKEEVKEAYM 91
Query: 354 GNVCSANLGQAPARQAVIFAGLPKSTICTTVNKVCASGMKSIMLAAQGLQTGAQDIILAG 533
GNV GQAP RQAV+ AGLP ST CTT+NKVCASGMK+IM+A+Q L G QD+++AG
Sbjct: 92 GNVLQGGEGQAPTRQAVLGAGLPISTPCTTINKVCASGMKAIMMASQSLMCGHQDVMVAG 151
Query: 534 GMESMSNVPFYLKRGETSYGGMQLVDGIVFDGLTDVYNKFHMGNCAENTAQKLQITRXDQ 713
GMESMSNVP+ + RG T YGG++L D IV DGLTDVYNK HMG+CAENTA+KL I R +Q
Sbjct: 152 GMESMSNVPYVMNRGSTPYGGVKLEDLIVKDGLTDVYNKIHMGSCAENTAKKLNIARNEQ 211
Query: 714 DXYAVHSYXRSXXXXXXXXFVDELVPVPVPXKEGLLLIFAEDEEYKXVXF 863
D YA++SY RS F +E++PV V K ++ EDEEYK V F
Sbjct: 212 DAYAINSYTRSKAAWEAGKFGNEVIPVTVTVKGQPDVVVKEDEEYKRVDF 261
>D10511-1|BAA01387.1| 427|Homo sapiens mitochondrial
acetoacetyl-CoA thiolase protein.
Length = 427
Score = 255 bits (625), Expect = 1e-67
Identities = 126/230 (54%), Positives = 157/230 (68%)
Frame = +3
Query: 174 AFSTKVSLNEVVIASAVRTPMXXXXXXXXXXXXXXXXXXXVNAAIERAGIPKEEIKEVYI 353
++ +K +L EVVI SA RTP+ + AIE+AGIPKEE+KE Y+
Sbjct: 32 SYVSKPTLKEVVIVSATRTPIGSFLGSLSLLPATKLGSIAIQGAIEKAGIPKEEVKEAYM 91
Query: 354 GNVCSANLGQAPARQAVIFAGLPKSTICTTVNKVCASGMKSIMLAAQGLQTGAQDIILAG 533
GNV GQAP RQAV+ AGLP ST CTT+NKVCASGMK+IM+A+Q L G QD+++AG
Sbjct: 92 GNVLQGGEGQAPTRQAVLGAGLPISTPCTTINKVCASGMKAIMMASQSLMCGHQDVMVAG 151
Query: 534 GMESMSNVPFYLKRGETSYGGMQLVDGIVFDGLTDVYNKFHMGNCAENTAQKLQITRXDQ 713
GMESMSNVP+ + RG T YGG++L D IV DGLTDVYNK HMG+CAENTA+KL I R +Q
Sbjct: 152 GMESMSNVPYVMNRGSTPYGGVKLEDLIVKDGLTDVYNKIHMGSCAENTAKKLNIARNEQ 211
Query: 714 DXYAVHSYXRSXXXXXXXXFVDELVPVPVPXKEGLLLIFAEDEEYKXVXF 863
D YA++SY RS F +E++PV V K ++ EDEEYK V F
Sbjct: 212 DAYAINSYTRSKAAWEAGKFGNEVIPVTVTVKGQPDVVVKEDEEYKRVDF 261
>AL135914-6|CAI21850.1| 397|Homo sapiens acetyl-Coenzyme A
acetyltransferase 2 (acetoacetyl Coenzyme A thiolase)
protein.
Length = 397
Score = 144 bits (348), Expect = 5e-34
Identities = 80/214 (37%), Positives = 115/214 (53%), Gaps = 2/214 (0%)
Frame = +3
Query: 204 VVIASAVRTPMXXXXXXXXXXXXXXXXXXXVNAAIERAGIPKEEIKEVYIGNVCSANLGQ 383
VVI SA RT + + ++RA + E++ EV G+V +A GQ
Sbjct: 8 VVIVSAARTIIGSFNGALAAVPVQDLGSTVIKEVLKRATVAPEDVSEVIFGHVLAAGCGQ 67
Query: 384 APARQAVIFAGLPKSTICTTVNKVCASGMKSIMLAAQGLQTGAQDIILAGGMESMSNVPF 563
P RQA + AG+P S + +C SG+K++ LA Q + G I++AGGME+MS P
Sbjct: 68 NPVRQASVGAGIPYSVPAWSCQMICGSGLKAVCLAVQSIGIGDSSIVVAGGMENMSKAPH 127
Query: 564 --YLKRGETSYGGMQLVDGIVFDGLTDVYNKFHMGNCAENTAQKLQITRXDQDXYAVHSY 737
YL+ G G M L D I+ DGLTD ++ HMG AEN A+K Q++R DQD AV S
Sbjct: 128 LAYLRTG-VKIGEMPLTDSILCDGLTDAFHNCHMGITAENVAKKWQVSREDQDKVAVLSQ 186
Query: 738 XRSXXXXXXXXFVDELVPVPVPXKEGLLLIFAED 839
R+ F E+VPV V ++GL+ + ++
Sbjct: 187 NRTENAQKAGHFDKEIVPVLVSTRKGLIEVKTDE 220
>AF356877-1|AAM00223.1| 397|Homo sapiens acetyl CoA
transferase-like protein protein.
Length = 397
Score = 144 bits (348), Expect = 5e-34
Identities = 80/214 (37%), Positives = 115/214 (53%), Gaps = 2/214 (0%)
Frame = +3
Query: 204 VVIASAVRTPMXXXXXXXXXXXXXXXXXXXVNAAIERAGIPKEEIKEVYIGNVCSANLGQ 383
VVI SA RT + + ++RA + E++ EV G+V +A GQ
Sbjct: 8 VVIVSAARTIIGSFNGALAAVPVQDLGSTVIKEVLKRATVAPEDVSEVIFGHVLAAGCGQ 67
Query: 384 APARQAVIFAGLPKSTICTTVNKVCASGMKSIMLAAQGLQTGAQDIILAGGMESMSNVPF 563
P RQA + AG+P S + +C SG+K++ LA Q + G I++AGGME+MS P
Sbjct: 68 NPVRQASVGAGIPYSVPAWSCQMICGSGLKAVCLAVQSIGIGDSSIVVAGGMENMSKAPH 127
Query: 564 --YLKRGETSYGGMQLVDGIVFDGLTDVYNKFHMGNCAENTAQKLQITRXDQDXYAVHSY 737
YL+ G G M L D I+ DGLTD ++ HMG AEN A+K Q++R DQD AV S
Sbjct: 128 LAYLRTG-VKIGEMPLTDSILCDGLTDAFHNCHMGITAENVAKKWQVSREDQDKVAVLSQ 186
Query: 738 XRSXXXXXXXXFVDELVPVPVPXKEGLLLIFAED 839
R+ F E+VPV V ++GL+ + ++
Sbjct: 187 NRTENAQKAGHFDKEIVPVLVSTRKGLIEVKTDE 220
>BC000408-1|AAH00408.1| 397|Homo sapiens ACAT2 protein protein.
Length = 397
Score = 143 bits (347), Expect = 7e-34
Identities = 80/214 (37%), Positives = 114/214 (53%), Gaps = 2/214 (0%)
Frame = +3
Query: 204 VVIASAVRTPMXXXXXXXXXXXXXXXXXXXVNAAIERAGIPKEEIKEVYIGNVCSANLGQ 383
VVI SA RT + + ++RA + E++ EV G+V +A GQ
Sbjct: 8 VVIVSAARTIIGSFNGALAAVPVQDLGSTVIKEVLKRATVAPEDVSEVIFGHVLAAGCGQ 67
Query: 384 APARQAVIFAGLPKSTICTTVNKVCASGMKSIMLAAQGLQTGAQDIILAGGMESMSNVPF 563
P RQA + AG+P S + +C SG+K++ LA Q + G I++AGGME+MS P
Sbjct: 68 NPVRQASVGAGIPYSVPAWSCQMICGSGLKAVCLAVQSIGIGDSSIVVAGGMENMSKAPH 127
Query: 564 --YLKRGETSYGGMQLVDGIVFDGLTDVYNKFHMGNCAENTAQKLQITRXDQDXYAVHSY 737
YL+ G G M L D I+ DGLTD ++ HMG AEN A+K Q++R DQD AV S
Sbjct: 128 LAYLRTG-VKIGEMPLTDSILCDGLTDAFHNCHMGITAENVAKKWQVSREDQDKVAVLSQ 186
Query: 738 XRSXXXXXXXXFVDELVPVPVPXKEGLLLIFAED 839
R+ F E+VPV V + GL+ + ++
Sbjct: 187 NRTENAQKAGHFDKEIVPVLVSTRRGLIEVKTDE 220
>AB208993-1|BAD92230.1| 404|Homo sapiens Acetyl-CoA
acetyltransferase, cytosolic variant protein.
Length = 404
Score = 143 bits (347), Expect = 7e-34
Identities = 80/214 (37%), Positives = 114/214 (53%), Gaps = 2/214 (0%)
Frame = +3
Query: 204 VVIASAVRTPMXXXXXXXXXXXXXXXXXXXVNAAIERAGIPKEEIKEVYIGNVCSANLGQ 383
VVI SA RT + + ++RA + E++ EV G+V +A GQ
Sbjct: 15 VVIVSAARTIIGSFNGALAAVPVQDLGSTVIKEVLKRATVAPEDVSEVIFGHVLAAGCGQ 74
Query: 384 APARQAVIFAGLPKSTICTTVNKVCASGMKSIMLAAQGLQTGAQDIILAGGMESMSNVPF 563
P RQA + AG+P S + +C SG+K++ LA Q + G I++AGGME+MS P
Sbjct: 75 NPVRQASVGAGIPYSVPAWSCQMICGSGLKAVCLAVQSIGIGDSSIVVAGGMENMSKAPH 134
Query: 564 --YLKRGETSYGGMQLVDGIVFDGLTDVYNKFHMGNCAENTAQKLQITRXDQDXYAVHSY 737
YL+ G G M L D I+ DGLTD ++ HMG AEN A+K Q++R DQD AV S
Sbjct: 135 LAYLRTG-VKIGEMPLTDSILCDGLTDAFHNCHMGITAENVAKKWQVSREDQDKVAVLSQ 193
Query: 738 XRSXXXXXXXXFVDELVPVPVPXKEGLLLIFAED 839
R+ F E+VPV V + GL+ + ++
Sbjct: 194 NRTENAQKAGHFDKEIVPVLVSTRRGLIEVKTDE 227
>S70154-1|AAB30856.1| 397|Homo sapiens cytosolic
acetoacetyl-coenzyme A thiolase protein.
Length = 397
Score = 143 bits (346), Expect = 9e-34
Identities = 80/214 (37%), Positives = 114/214 (53%), Gaps = 2/214 (0%)
Frame = +3
Query: 204 VVIASAVRTPMXXXXXXXXXXXXXXXXXXXVNAAIERAGIPKEEIKEVYIGNVCSANLGQ 383
VVI SA RT + + ++RA + E++ EV G+V +A GQ
Sbjct: 8 VVIVSAARTIIGSFNGALAAVPVQDLGSTVIKEVLKRATVAPEDVSEVIFGHVLAAGCGQ 67
Query: 384 APARQAVIFAGLPKSTICTTVNKVCASGMKSIMLAAQGLQTGAQDIILAGGMESMSNVPF 563
P RQA + AG+P S + +C SG+K++ LA Q + G I++AGGME+MS P
Sbjct: 68 NPVRQASVGAGIPYSVPAWSCQMICGSGLKAVCLAVQSIGIGDSSIVVAGGMENMSKAPH 127
Query: 564 --YLKRGETSYGGMQLVDGIVFDGLTDVYNKFHMGNCAENTAQKLQITRXDQDXYAVHSY 737
YL+ G G M L D I+ DGLTD ++ HMG AEN A K Q++R DQD AV S
Sbjct: 128 LAYLRTG-VKIGEMPLTDSILCDGLTDAFHNCHMGITAENVATKWQVSREDQDKVAVLSQ 186
Query: 738 XRSXXXXXXXXFVDELVPVPVPXKEGLLLIFAED 839
R+ F E+VPV V ++GL+ + ++
Sbjct: 187 NRTENAQKAGHFDKEIVPVLVSTRKGLIEVKTDE 220
>BC010942-1|AAH10942.1| 162|Homo sapiens ACAT1 protein protein.
Length = 162
Score = 120 bits (289), Expect = 7e-27
Identities = 60/114 (52%), Positives = 74/114 (64%)
Frame = +3
Query: 174 AFSTKVSLNEVVIASAVRTPMXXXXXXXXXXXXXXXXXXXVNAAIERAGIPKEEIKEVYI 353
++ +K +L EVVI SA RTP+ + AIE+AGIPKEE+KE Y+
Sbjct: 32 SYVSKPTLKEVVIVSATRTPIGSFLGSLSLLPATKLGSIAIQGAIEKAGIPKEEVKEAYM 91
Query: 354 GNVCSANLGQAPARQAVIFAGLPKSTICTTVNKVCASGMKSIMLAAQGLQTGAQ 515
GNV GQAP RQAV+ AGLP ST CTT+NKVCASGMK+IM+A+Q L G Q
Sbjct: 92 GNVLQGGEGQAPTRQAVLGAGLPISTPCTTINKVCASGMKAIMMASQSLMCGHQ 145
>BC063853-1|AAH63853.1| 289|Homo sapiens ACAT1 protein protein.
Length = 289
Score = 118 bits (285), Expect = 2e-26
Identities = 69/172 (40%), Positives = 97/172 (56%), Gaps = 6/172 (3%)
Frame = +3
Query: 366 SANLGQAPARQAVIFAGLPKSTICTTVNKVCASGMKSIMLAAQGLQTGAQDIILAGGMES 545
+ LG + A+ AG+PK +V + M +++ +G Q + +L G +
Sbjct: 64 ATKLGSIAIQGAIEKAGIPKE-------EVKEAYMGNVLQGGEG-QAPTRQAVLGAGCDG 115
Query: 546 MS------NVPFYLKRGETSYGGMQLVDGIVFDGLTDVYNKFHMGNCAENTAQKLQITRX 707
+VP+ + RG T YGG++L D IV DGLTDVYNK HMG+CAENTA+KL I R
Sbjct: 116 GRWDGEHVHVPYVMNRGSTPYGGVKLEDLIVKDGLTDVYNKIHMGSCAENTAKKLNIARN 175
Query: 708 DQDXYAVHSYXRSXXXXXXXXFVDELVPVPVPXKEGLLLIFAEDEEYKXVXF 863
+QD YA++SY RS F +E++PV V K ++ EDEEYK V F
Sbjct: 176 EQDAYAINSYTRSKAAWEAGKFGNEVIPVTVTVKGQPDVVVKEDEEYKRVDF 227
Score = 72.9 bits (171), Expect = 1e-12
Identities = 37/81 (45%), Positives = 47/81 (58%)
Frame = +3
Query: 174 AFSTKVSLNEVVIASAVRTPMXXXXXXXXXXXXXXXXXXXVNAAIERAGIPKEEIKEVYI 353
++ +K +L EVVI SA RTP+ + AIE+AGIPKEE+KE Y+
Sbjct: 32 SYVSKPTLKEVVIVSATRTPIGSFLGSLSLLPATKLGSIAIQGAIEKAGIPKEEVKEAYM 91
Query: 354 GNVCSANLGQAPARQAVIFAG 416
GNV GQAP RQAV+ AG
Sbjct: 92 GNVLQGGEGQAPTRQAVLGAG 112
>BC001918-1|AAH01918.1| 397|Homo sapiens acetyl-Coenzyme A
acyltransferase 2 (mitochondrial 3-oxoacyl-Coenzyme A
thiolas protein.
Length = 397
Score = 95.9 bits (228), Expect = 2e-19
Identities = 64/230 (27%), Positives = 102/230 (44%), Gaps = 3/230 (1%)
Frame = +3
Query: 195 LNEVVIASAVRTPMXXXXXXXXXXXXXXXXXXXVNAAIERAGIPKEEIKEVYIGNVCSAN 374
L V + +A RTP AA+ + E + V +GNV ++
Sbjct: 4 LRGVFVVAAKRTPFGAYGGLLKDFTATDLSEFAAKAALSAGKVSPETVDSVIMGNVLQSS 63
Query: 375 LGQAP-ARQAVIFAGLPKSTICTTVNKVCASGMKSIMLAAQGLQTGAQDIILAGGMESMS 551
AR + G+PK T T+N++C SG +SI+ Q + +++L GG ESMS
Sbjct: 64 SDAIYLARHVGLRVGIPKETPALTINRLCGSGFQSIVNGCQEICVKEAEVVLCGGTESMS 123
Query: 552 NVPFYLK--RGETSYGGMQLVDGIVFDGLTDVYNKFHMGNCAENTAQKLQITRXDQDXYA 725
P+ ++ R T G ++ ++ LTD + + M AEN A K +I+R + D YA
Sbjct: 124 QAPYCVRNVRFGTKLGSDIKLEDSLWVSLTDQHVQLPMAMTAENLAVKHKISREECDKYA 183
Query: 726 VHSYXRSXXXXXXXXFVDELVPVPVPXKEGLLLIFAEDEEYKXVXFEXLQ 875
+ S R F DE+ P+ V K+G + ++ E LQ
Sbjct: 184 LQSQQRWKAANDAGYFNDEMAPIEVKTKKGKQTMQVDEHARPQTTLEQLQ 233
>D16294-1|BAA03800.1| 397|Homo sapiens mitochondrial 3-oxoacyl-CoA
thiolase protein.
Length = 397
Score = 94.3 bits (224), Expect = 5e-19
Identities = 63/230 (27%), Positives = 101/230 (43%), Gaps = 3/230 (1%)
Frame = +3
Query: 195 LNEVVIASAVRTPMXXXXXXXXXXXXXXXXXXXVNAAIERAGIPKEEIKEVYIGNVCSAN 374
L V + +A RTP AA+ + E + V +GNV ++
Sbjct: 4 LRGVFVVAAKRTPFGAYGGLLKDFTATDLSEFAAKAALSAGKVSPETVDSVIMGNVLQSS 63
Query: 375 LGQAP-ARQAVIFAGLPKSTICTTVNKVCASGMKSIMLAAQGLQTGAQDIILAGGMESMS 551
AR + G+PK T T+N++C SG +SI+ Q + +++L GG ESMS
Sbjct: 64 SDAIYLARHVGLRVGIPKETPALTINRLCGSGFQSIVNGCQEICVKEAEVVLCGGTESMS 123
Query: 552 NVPFYLK--RGETSYGGMQLVDGIVFDGLTDVYNKFHMGNCAENTAQKLQITRXDQDXYA 725
P+ ++ R T G ++ ++ LTD + + M AEN K +I+R + D YA
Sbjct: 124 QAPYCVRNVRFGTKLGSDIKLEDSLWVSLTDQHVQLPMAMTAENLTVKHKISREECDKYA 183
Query: 726 VHSYXRSXXXXXXXXFVDELVPVPVPXKEGLLLIFAEDEEYKXVXFEXLQ 875
+ S R F DE+ P+ V K+G + ++ E LQ
Sbjct: 184 LQSQQRWKAANDAGYFNDEMAPIEVKTKKGKQTMQVDEHARPQTTLEQLQ 233
>X65140-1|CAA46270.1| 424|Homo sapiens peroxisomal 3-oxoacyl-CoA
thiolase protein.
Length = 424
Score = 71.3 bits (167), Expect = 4e-12
Identities = 47/167 (28%), Positives = 85/167 (50%)
Frame = +3
Query: 294 VNAAIERAGIPKEEIKEVYIGNVCSANLGQAPARQAVIFAGLPKSTICTTVNKVCASGMK 473
+ A ++ + E++ ++ +GNV G AR A + +P++ +TVN+ C+SG++
Sbjct: 69 MTAVLKDVNLRPEQLGDICVGNVLQPGAGAIMARIAQFLSDIPETVPLSTVNRQCSSGLQ 128
Query: 474 SIMLAAQGLQTGAQDIILAGGMESMSNVPFYLKRGETSYGGMQLVDGIVFDGLTDVYNKF 653
++ A G++ G+ DI +A G+ESMS RG +L++ + D
Sbjct: 129 AVASIAGGIRNGSYDIGMACGVESMS----LADRGNPGNITSRLMEK---EKARDCL--I 179
Query: 654 HMGNCAENTAQKLQITRXDQDXYAVHSYXRSXXXXXXXXFVDELVPV 794
MG +EN A++ I+R QD +A+ S ++ F E+VPV
Sbjct: 180 PMGITSENVAERFGISREKQDTFALASQQKAARAQSKGCFQAEIVPV 226
>X14813-1|CAA32918.1| 424|Homo sapiens protein ( Human liver mRNA
for 3-oxoacyl-CoA thiolase. ).
Length = 424
Score = 71.3 bits (167), Expect = 4e-12
Identities = 47/167 (28%), Positives = 85/167 (50%)
Frame = +3
Query: 294 VNAAIERAGIPKEEIKEVYIGNVCSANLGQAPARQAVIFAGLPKSTICTTVNKVCASGMK 473
+ A ++ + E++ ++ +GNV G AR A + +P++ +TVN+ C+SG++
Sbjct: 69 MTAVLKDVNLRPEQLGDICVGNVLQPGAGAIMARIAQFLSDIPETVPLSTVNRQCSSGLQ 128
Query: 474 SIMLAAQGLQTGAQDIILAGGMESMSNVPFYLKRGETSYGGMQLVDGIVFDGLTDVYNKF 653
++ A G++ G+ DI +A G+ESMS RG +L++ + D
Sbjct: 129 AVASIAGGIRNGSYDIGMACGVESMS----LADRGNPGNITSRLMEK---EKARDCL--I 179
Query: 654 HMGNCAENTAQKLQITRXDQDXYAVHSYXRSXXXXXXXXFVDELVPV 794
MG +EN A++ I+R QD +A+ S ++ F E+VPV
Sbjct: 180 PMGITSENVAERFGISREKQDTFALASQQKAARAQSKGCFQAEIVPV 226
>X12966-1|CAA31412.1| 424|Homo sapiens protein ( Human mRNA for
3-oxoacyl-CoA peroxisomal thiolase. ).
Length = 424
Score = 71.3 bits (167), Expect = 4e-12
Identities = 47/167 (28%), Positives = 85/167 (50%)
Frame = +3
Query: 294 VNAAIERAGIPKEEIKEVYIGNVCSANLGQAPARQAVIFAGLPKSTICTTVNKVCASGMK 473
+ A ++ + E++ ++ +GNV G AR A + +P++ +TVN+ C+SG++
Sbjct: 69 MTAVLKDVNLRPEQLGDICVGNVLQPGAGAIMARIAQFLSDIPETVPLSTVNRQCSSGLQ 128
Query: 474 SIMLAAQGLQTGAQDIILAGGMESMSNVPFYLKRGETSYGGMQLVDGIVFDGLTDVYNKF 653
++ A G++ G+ DI +A G+ESMS RG +L++ + D
Sbjct: 129 AVASIAGGIRNGSYDIGMACGVESMS----LADRGNPGNITSRLMEK---EKARDCL--I 179
Query: 654 HMGNCAENTAQKLQITRXDQDXYAVHSYXRSXXXXXXXXFVDELVPV 794
MG +EN A++ I+R QD +A+ S ++ F E+VPV
Sbjct: 180 PMGITSENVAERFGISREKQDTFALASQQKAARAQSKGCFQAEIVPV 226
>BC011977-1|AAH11977.1| 424|Homo sapiens acetyl-Coenzyme A
acyltransferase 1 (peroxisomal 3-oxoacyl-Coenzyme A
thiolase) protein.
Length = 424
Score = 71.3 bits (167), Expect = 4e-12
Identities = 47/167 (28%), Positives = 85/167 (50%)
Frame = +3
Query: 294 VNAAIERAGIPKEEIKEVYIGNVCSANLGQAPARQAVIFAGLPKSTICTTVNKVCASGMK 473
+ A ++ + E++ ++ +GNV G AR A + +P++ +TVN+ C+SG++
Sbjct: 69 MTAVLKDVNLRPEQLGDICVGNVLQPGAGAIMARIAQFLSDIPETVPLSTVNRQCSSGLQ 128
Query: 474 SIMLAAQGLQTGAQDIILAGGMESMSNVPFYLKRGETSYGGMQLVDGIVFDGLTDVYNKF 653
++ A G++ G+ DI +A G+ESMS RG +L++ + D
Sbjct: 129 AVASIAGGIRNGSYDIGMACGVESMS----LADRGNPGNITSRLMEK---EKARDCL--I 179
Query: 654 HMGNCAENTAQKLQITRXDQDXYAVHSYXRSXXXXXXXXFVDELVPV 794
MG +EN A++ I+R QD +A+ S ++ F E+VPV
Sbjct: 180 PMGITSENVAERFGISREKQDTFALASQQKAARAQSKGCFQAEIVPV 226
>BC000635-1|AAH00635.1| 424|Homo sapiens acetyl-Coenzyme A
acyltransferase 1 (peroxisomal 3-oxoacyl-Coenzyme A
thiolase) protein.
Length = 424
Score = 71.3 bits (167), Expect = 4e-12
Identities = 47/167 (28%), Positives = 85/167 (50%)
Frame = +3
Query: 294 VNAAIERAGIPKEEIKEVYIGNVCSANLGQAPARQAVIFAGLPKSTICTTVNKVCASGMK 473
+ A ++ + E++ ++ +GNV G AR A + +P++ +TVN+ C+SG++
Sbjct: 69 MTAVLKDVNLRPEQLGDICVGNVLQPGAGAIMARIAQFLSDIPETVPLSTVNRQCSSGLQ 128
Query: 474 SIMLAAQGLQTGAQDIILAGGMESMSNVPFYLKRGETSYGGMQLVDGIVFDGLTDVYNKF 653
++ A G++ G+ DI +A G+ESMS RG +L++ + D
Sbjct: 129 AVASIAGGIRNGSYDIGMACGVESMS----LADRGNPGNITSRLMEK---EKARDCL--I 179
Query: 654 HMGNCAENTAQKLQITRXDQDXYAVHSYXRSXXXXXXXXFVDELVPV 794
MG +EN A++ I+R QD +A+ S ++ F E+VPV
Sbjct: 180 PMGITSENVAERFGISREKQDTFALASQQKAARAQSKGCFQAEIVPV 226
>BC014572-1|AAH14572.1| 475|Homo sapiens hydroxyacyl-Coenzyme A
dehydrogenase/3-ketoacyl-Coenzyme A thiolase/enoyl-Coenz
protein.
Length = 475
Score = 66.5 bits (155), Expect = 1e-10
Identities = 54/227 (23%), Positives = 93/227 (40%), Gaps = 18/227 (7%)
Frame = +3
Query: 186 KVSLNEVVIASAVRTPMXXXXXXXXXXXXXXXXXXXVNAAIERAGIPKEEIKEVYIGNVC 365
K ++ VV+ VRTP + + R +PKE + + G V
Sbjct: 49 KPNIRNVVVVDGVRTPFLLSGTSYKDLMPHDLARAALTGLLHRTSVPKEVVDYIIFGTVI 108
Query: 366 SANLGQAPARQAVIFAGLPKSTICTTVNKVCASGMKSIMLAAQGLQTGAQDIILAGGMES 545
AR+A + AG T TV C S +++ + +G D+I+AGG+E
Sbjct: 109 QEVKTSNVAREAALGAGFSDKTPAHTVTMACISANQAMTTGVGLIASGQCDVIVAGGVEL 168
Query: 546 MSNVPFY-----------LKRGETSYGGMQLVDGIVFDGLTD---VYNKFH----MGNCA 671
MS+VP L + ++ + L+ F+ L ++F MG+ A
Sbjct: 169 MSDVPIRHSRKMRKLMLDLNKAKSMGQRLSLISKFRFNFLASELPAVSEFSTSETMGHSA 228
Query: 672 ENTAQKLQITRXDQDXYAVHSYXRSXXXXXXXXFVDELVPVPVPXKE 812
+ A ++R +QD YA+ S+ + + ++VP VP K+
Sbjct: 229 DRLAAAFAVSRLEQDEYALRSHSLA-KKAQDEGLLSDVVPFKVPGKD 274
>D16481-1|BAA03942.1| 474|Homo sapiens 3-ketoacyl-CoA thiolase
beta-subunit of trifunctional protein protein.
Length = 474
Score = 66.1 bits (154), Expect = 2e-10
Identities = 54/227 (23%), Positives = 93/227 (40%), Gaps = 18/227 (7%)
Frame = +3
Query: 186 KVSLNEVVIASAVRTPMXXXXXXXXXXXXXXXXXXXVNAAIERAGIPKEEIKEVYIGNVC 365
K ++ VV+ VRTP + + R +PKE + + G V
Sbjct: 48 KPNIRNVVVVDGVRTPFLLSGTSYKDLMPHDLARAALTGLLHRTSVPKEVVDYIIFGTVI 107
Query: 366 SANLGQAPARQAVIFAGLPKSTICTTVNKVCASGMKSIMLAAQGLQTGAQDIILAGGMES 545
AR+A + AG T TV C S +++ + +G D+I+AGG+E
Sbjct: 108 QEVKTSNVAREAALGAGFSDKTPAHTVTMACISANQAMTTGVGLIASGQCDVIVAGGVEL 167
Query: 546 MSNVPFY-----------LKRGETSYGGMQLVDGIVFDGLT---DVYNKFH----MGNCA 671
MS+VP L + ++ + L+ F+ L ++F MG+ A
Sbjct: 168 MSDVPIRHSRKMRKLMLDLNKAKSMGQRLSLISKFRFNFLAPELPAVSEFSTSETMGHSA 227
Query: 672 ENTAQKLQITRXDQDXYAVHSYXRSXXXXXXXXFVDELVPVPVPXKE 812
+ A ++R +QD YA+ S+ + + ++VP VP K+
Sbjct: 228 DRLAAAFAVSRLEQDEYALRSHSLA-KKAQDEGLLSDVVPFKVPGKD 273
>BC066963-1|AAH66963.1| 475|Homo sapiens hydroxyacyl-Coenzyme A
dehydrogenase/3-ketoacyl-Coenzyme A thiolase/enoyl-Coenz
protein.
Length = 475
Score = 66.1 bits (154), Expect = 2e-10
Identities = 54/227 (23%), Positives = 93/227 (40%), Gaps = 18/227 (7%)
Frame = +3
Query: 186 KVSLNEVVIASAVRTPMXXXXXXXXXXXXXXXXXXXVNAAIERAGIPKEEIKEVYIGNVC 365
K ++ VV+ VRTP + + R +PKE + + G V
Sbjct: 49 KPNIRNVVVVDGVRTPFLLSGTSYKDLMPHDLARAALTGLLHRTSVPKEVVDYIIFGTVI 108
Query: 366 SANLGQAPARQAVIFAGLPKSTICTTVNKVCASGMKSIMLAAQGLQTGAQDIILAGGMES 545
AR+A + AG T TV C S +++ + +G D+I+AGG+E
Sbjct: 109 QEVKTSNVAREAALGAGFSDKTPAHTVTMACISANQAMTTGVGLIASGQCDVIVAGGVEL 168
Query: 546 MSNVPFY-----------LKRGETSYGGMQLVDGIVFDGLT---DVYNKFH----MGNCA 671
MS+VP L + ++ + L+ F+ L ++F MG+ A
Sbjct: 169 MSDVPIRHSRKMRKLMLDLNKAKSMGQRLSLISKFRFNFLAPELPAVSEFSTSETMGHSA 228
Query: 672 ENTAQKLQITRXDQDXYAVHSYXRSXXXXXXXXFVDELVPVPVPXKE 812
+ A ++R +QD YA+ S+ + + ++VP VP K+
Sbjct: 229 DRLAAAFAVSRLEQDEYALRSHSLA-KKAQDEGLLSDVVPFKVPGKD 274
>BC030824-1|AAH30824.1| 475|Homo sapiens hydroxyacyl-Coenzyme A
dehydrogenase/3-ketoacyl-Coenzyme A thiolase/enoyl-Coenz
protein.
Length = 475
Score = 66.1 bits (154), Expect = 2e-10
Identities = 54/227 (23%), Positives = 93/227 (40%), Gaps = 18/227 (7%)
Frame = +3
Query: 186 KVSLNEVVIASAVRTPMXXXXXXXXXXXXXXXXXXXVNAAIERAGIPKEEIKEVYIGNVC 365
K ++ VV+ VRTP + + R +PKE + + G V
Sbjct: 49 KPNIRNVVVVDGVRTPFLLSGTSYKDLMPHDLARAALTGLLHRTSVPKEVVDYIIFGTVI 108
Query: 366 SANLGQAPARQAVIFAGLPKSTICTTVNKVCASGMKSIMLAAQGLQTGAQDIILAGGMES 545
AR+A + AG T TV C S +++ + +G D+I+AGG+E
Sbjct: 109 QEVKTSNVAREAALGAGFSDKTPAHTVTMACISANQAMTTGVGLIASGQCDVIVAGGVEL 168
Query: 546 MSNVPFY-----------LKRGETSYGGMQLVDGIVFDGLT---DVYNKFH----MGNCA 671
MS+VP L + ++ + L+ F+ L ++F MG+ A
Sbjct: 169 MSDVPIRHSRKMRKLMLDLNKAKSMGQRLSLISKFRFNFLAPELPAVSEFSTSETMGHSA 228
Query: 672 ENTAQKLQITRXDQDXYAVHSYXRSXXXXXXXXFVDELVPVPVPXKE 812
+ A ++R +QD YA+ S+ + + ++VP VP K+
Sbjct: 229 DRLAAAFAVSRLEQDEYALRSHSLA-KKAQDEGLLSDVVPFKVPGKD 274
>BC017564-1|AAH17564.1| 475|Homo sapiens hydroxyacyl-Coenzyme A
dehydrogenase/3-ketoacyl-Coenzyme A thiolase/enoyl-Coenz
protein.
Length = 475
Score = 66.1 bits (154), Expect = 2e-10
Identities = 54/227 (23%), Positives = 93/227 (40%), Gaps = 18/227 (7%)
Frame = +3
Query: 186 KVSLNEVVIASAVRTPMXXXXXXXXXXXXXXXXXXXVNAAIERAGIPKEEIKEVYIGNVC 365
K ++ VV+ VRTP + + R +PKE + + G V
Sbjct: 49 KPNIRNVVVVDGVRTPFLLSGTSYKDLMPHDLARAALTGLLHRTSVPKEVVDYIIFGTVI 108
Query: 366 SANLGQAPARQAVIFAGLPKSTICTTVNKVCASGMKSIMLAAQGLQTGAQDIILAGGMES 545
AR+A + AG T TV C S +++ + +G D+I+AGG+E
Sbjct: 109 QEVKTSNVAREAALGAGFSDKTPAHTVTMACISANQAMTTGVGLIASGQCDVIVAGGVEL 168
Query: 546 MSNVPFY-----------LKRGETSYGGMQLVDGIVFDGLT---DVYNKFH----MGNCA 671
MS+VP L + ++ + L+ F+ L ++F MG+ A
Sbjct: 169 MSDVPIRHSRKMRKLMLDLNKAKSMGQRLSLISKFRFNFLAPELPAVSEFSTSETMGHSA 228
Query: 672 ENTAQKLQITRXDQDXYAVHSYXRSXXXXXXXXFVDELVPVPVPXKE 812
+ A ++R +QD YA+ S+ + + ++VP VP K+
Sbjct: 229 DRLAAAFAVSRLEQDEYALRSHSLA-KKAQDEGLLSDVVPFKVPGKD 274
>AC010896-2|AAY14644.1| 474|Homo sapiens unknown protein.
Length = 474
Score = 66.1 bits (154), Expect = 2e-10
Identities = 54/227 (23%), Positives = 93/227 (40%), Gaps = 18/227 (7%)
Frame = +3
Query: 186 KVSLNEVVIASAVRTPMXXXXXXXXXXXXXXXXXXXVNAAIERAGIPKEEIKEVYIGNVC 365
K ++ VV+ VRTP + + R +PKE + + G V
Sbjct: 48 KPNIRNVVVVDGVRTPFLLSGTSYKDLMPHDLARAALTGLLHRTSVPKEVVDYIIFGTVI 107
Query: 366 SANLGQAPARQAVIFAGLPKSTICTTVNKVCASGMKSIMLAAQGLQTGAQDIILAGGMES 545
AR+A + AG T TV C S +++ + +G D+I+AGG+E
Sbjct: 108 QEVKTSNVAREAALGAGFSDKTPAHTVTMACISANQAMTTGVGLIASGQCDVIVAGGVEL 167
Query: 546 MSNVPFY-----------LKRGETSYGGMQLVDGIVFDGLT---DVYNKFH----MGNCA 671
MS+VP L + ++ + L+ F+ L ++F MG+ A
Sbjct: 168 MSDVPIRHSRKMRKLMLDLNKAKSMGQRLSLISKFRFNFLAPELPAVSEFSTSETMGHSA 227
Query: 672 ENTAQKLQITRXDQDXYAVHSYXRSXXXXXXXXFVDELVPVPVPXKE 812
+ A ++R +QD YA+ S+ + + ++VP VP K+
Sbjct: 228 DRLAAAFAVSRLEQDEYALRSHSLA-KKAQDEGLLSDVVPFKVPGKD 273
>BC014474-1|AAH14474.1| 331|Homo sapiens ACAA1 protein protein.
Length = 331
Score = 53.6 bits (123), Expect(2) = 7e-10
Identities = 24/84 (28%), Positives = 49/84 (58%)
Frame = +3
Query: 294 VNAAIERAGIPKEEIKEVYIGNVCSANLGQAPARQAVIFAGLPKSTICTTVNKVCASGMK 473
+ A ++ + E++ ++ +GNV G AR A + +P++ +TVN+ C+SG++
Sbjct: 69 MTAVLKDVNLRPEQLGDICVGNVLQPGAGAIMARIAQFLSDIPETVPLSTVNRQCSSGLQ 128
Query: 474 SIMLAAQGLQTGAQDIILAGGMES 545
++ A G++ G+ DI +A G+ S
Sbjct: 129 AVASIAGGIRNGSYDIGMACGITS 152
Score = 30.3 bits (65), Expect(2) = 7e-10
Identities = 15/45 (33%), Positives = 24/45 (53%)
Frame = +3
Query: 660 GNCAENTAQKLQITRXDQDXYAVHSYXRSXXXXXXXXFVDELVPV 794
G +EN A++ I+R QD +A+ S ++ F E+VPV
Sbjct: 149 GITSENVAERFGISREKQDTFALASQQKAARAQSKGCFQAEIVPV 193
>X51460-1|CAA35825.1| 326|Homo sapiens 3-oxoacyl-CoA thiolase
protein.
Length = 326
Score = 58.0 bits (134), Expect = 4e-08
Identities = 41/135 (30%), Positives = 70/135 (51%)
Frame = +3
Query: 390 ARQAVIFAGLPKSTICTTVNKVCASGMKSIMLAAQGLQTGAQDIILAGGMESMSNVPFYL 569
AR A + +P++ +TVN+ C+SG++++ A G++ G+ DI +A G+ESMS
Sbjct: 3 ARIAQFLSDIPETVPLSTVNRQCSSGLQAVASIAGGIRNGSYDIGMACGVESMS----LA 58
Query: 570 KRGETSYGGMQLVDGIVFDGLTDVYNKFHMGNCAENTAQKLQITRXDQDXYAVHSYXRSX 749
RG +L++ + D MG +EN A++ I+R QD +A+ S ++
Sbjct: 59 DRGNPGNITSRLMEK---EKARDCL--IPMGITSENVAERFGISREKQDTFALASQQKAA 113
Query: 750 XXXXXXXFVDELVPV 794
F E+VPV
Sbjct: 114 RAQSKGCFQAEIVPV 128
>U49441-1|AAB09424.1| 224|Homo sapiens mitochondrial trifunctional
protein beta subunit protein.
Length = 224
Score = 48.0 bits (109), Expect = 5e-05
Identities = 41/159 (25%), Positives = 70/159 (44%), Gaps = 18/159 (11%)
Frame = +3
Query: 390 ARQAVIFAGLPKSTICTTVNKVCASGMKSIMLAAQGLQTGAQDIILAGGMESMSNVPFY- 566
AR+A + AG T TV C S +++ A + +G D+++AGG+E MS+VP
Sbjct: 15 AREAALGAGFSDKTPAHTVTMACISSNQAMTTAVGLIASGQCDVVVAGGVELMSDVPIRH 74
Query: 567 ----------LKRGETSYGGMQLVDGIVFDGLT-------DVYNKFHMGNCAENTAQKLQ 695
L + +T + L+ + L+ + MG+ A+ A
Sbjct: 75 SRNMRKMMLDLNKAKTLGQRLSLLSKFRLNFLSPELPAVAEFSTNETMGHSADRLAAAFA 134
Query: 696 ITRXDQDXYAVHSYXRSXXXXXXXXFVDELVPVPVPXKE 812
++R +QD YA+ S+ + D +VP VP K+
Sbjct: 135 VSRMEQDEYALRSHSLAKKAQDEGHLSD-IVPFKVPGKD 172
>D86850-1|BAA22061.1| 410|Homo sapiens 3-ketoacyl-CoA thiolase
beta-subunit of mitochondrial trifunctional protein
protein.
Length = 410
Score = 46.4 bits (105), Expect = 1e-04
Identities = 45/182 (24%), Positives = 80/182 (43%), Gaps = 18/182 (9%)
Frame = +3
Query: 321 IPKEEIKEVYIGNVCSANLGQAPARQAVIFAGLPKSTICTTVNKVCASGMKSIMLAAQGL 500
+ + + KE G CS ++ A A + AG T TV C S +++ +
Sbjct: 30 VSQTQYKECCGGGWCSHSIF-AVWHFAALGAGFSDKTPAHTVTMACISANQAMTTGVGLI 88
Query: 501 QTGAQDIILAGGMESMSNVPFY-----------LKRGETSYGGMQLVDGIVFDGLT---D 638
+G D+I+AGG+E MS+VP L + ++ + L+ F+ L
Sbjct: 89 ASGQCDVIVAGGVELMSDVPIRHSRKMRKLMLDLNKAKSMGQRLSLISKFRFNFLAPELP 148
Query: 639 VYNKFH----MGNCAENTAQKLQITRXDQDXYAVHSYXRSXXXXXXXXFVDELVPVPVPX 806
++F MG+ A+ A ++R +QD YA+ S+ + + ++VP VP
Sbjct: 149 AVSEFSTSETMGHSADRLAAAFAVSRLEQDEYALRSHSLA-KKAQDEGLLSDVVPFKVPG 207
Query: 807 KE 812
K+
Sbjct: 208 KD 209
>AF035295-1|AAB88181.1| 132|Homo sapiens protein ( Homo sapiens
clone 23623 mRNA, partial cds. ).
Length = 132
Score = 40.7 bits (91), Expect = 0.007
Identities = 16/62 (25%), Positives = 36/62 (58%)
Frame = +3
Query: 294 VNAAIERAGIPKEEIKEVYIGNVCSANLGQAPARQAVIFAGLPKSTICTTVNKVCASGMK 473
+ A ++ + E++ ++ +GNV G AR A + +P++ +TVN+ C+SG++
Sbjct: 48 MTAVLKDVNLRPEQLGDICVGNVLQPGAGAIMARIAQFLSDIPETVPLSTVNRQCSSGLQ 107
Query: 474 SI 479
++
Sbjct: 108 AV 109
Database: human
Posted date: Oct 23, 2007 1:18 PM
Number of letters in database: 76,859,062
Number of sequences in database: 237,096
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 109,820,095
Number of Sequences: 237096
Number of extensions: 2249279
Number of successful extensions: 7782
Number of sequences better than 10.0: 27
Number of HSP's better than 10.0 without gapping: 7622
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 7771
length of database: 76,859,062
effective HSP length: 90
effective length of database: 55,520,422
effective search space used: 11548247776
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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