Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= MFBP02_F_N18
(892 letters)
Database: uniref50
1,657,284 sequences; 575,637,011 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
UniRef50_Q9Y020 Cluster: 3-dehydroecdysone 3beta-reductase precu... 204 3e-51
UniRef50_UPI00015B56A2 Cluster: PREDICTED: similar to GA10458-PA... 192 8e-48
UniRef50_UPI00015B56A3 Cluster: PREDICTED: similar to aldo-keto ... 190 5e-47
UniRef50_Q8WRT0 Cluster: 3-dehydrecdysone 3b-reductase; n=1; Tri... 188 1e-46
UniRef50_Q54B70 Cluster: Aldehyde reductase; n=2; Dictyostelium ... 171 2e-41
UniRef50_Q7PCV3 Cluster: ENSANGP00000031808; n=9; Endopterygota|... 171 3e-41
UniRef50_Q8VC28 Cluster: Aldo-keto reductase family 1 member C13... 171 3e-41
UniRef50_A3U9Y0 Cluster: Aldehyde reductase; n=5; Bacteroidetes|... 170 4e-41
UniRef50_Q2LZ66 Cluster: GA19341-PA; n=2; Endopterygota|Rep: GA1... 167 3e-40
UniRef50_UPI0000588153 Cluster: PREDICTED: hypothetical protein;... 166 8e-40
UniRef50_Q17DN0 Cluster: Aldo-keto reductase; n=5; Culicidae|Rep... 164 2e-39
UniRef50_Q7JVH6 Cluster: LD24696p; n=2; Sophophora|Rep: LD24696p... 161 2e-38
UniRef50_Q9VTL0 Cluster: CG6083-PA; n=4; Diptera|Rep: CG6083-PA ... 161 2e-38
UniRef50_A5E082 Cluster: GCY protein; n=4; Saccharomycetales|Rep... 161 2e-38
UniRef50_UPI00015B4B22 Cluster: PREDICTED: similar to GA15457-PA... 160 5e-38
UniRef50_Q968S3 Cluster: Aldoketoreductase-like protein; n=1; Or... 159 9e-38
UniRef50_Q8K023 Cluster: Aldo-keto reductase family 1 member C18... 159 9e-38
UniRef50_Q41399 Cluster: Chalcone reductase; n=4; eudicotyledons... 158 2e-37
UniRef50_Q2UGR1 Cluster: Aldo/keto reductase family proteins; n=... 158 2e-37
UniRef50_Q6TY50 Cluster: Reductase 2; n=10; Magnoliophyta|Rep: R... 157 3e-37
UniRef50_Q0VGY1 Cluster: 3-alpha-hydroxysteroid dehydrogenase; n... 156 6e-37
UniRef50_Q9NAI5 Cluster: Putative uncharacterized protein; n=3; ... 156 6e-37
UniRef50_P14550 Cluster: Alcohol dehydrogenase [NADP+]; n=44; Bi... 156 6e-37
UniRef50_P45376 Cluster: Aldose reductase; n=21; Bilateria|Rep: ... 155 1e-36
UniRef50_P26690 Cluster: NAD(P)H-dependent 6'-deoxychalcone synt... 155 1e-36
UniRef50_P15121 Cluster: Aldose reductase; n=72; Eumetazoa|Rep: ... 155 2e-36
UniRef50_UPI000065D0BD Cluster: Homolog of Homo sapiens "AKR1B1 ... 101 2e-36
UniRef50_Q8CI22 Cluster: 2310005E10Rik protein; n=30; Tetrapoda|... 154 2e-36
UniRef50_Q2S340 Cluster: Aldehyde reductase; n=10; Bacteria|Rep:... 154 2e-36
UniRef50_Q96UH3 Cluster: Aldehyde reductase; n=13; Pezizomycotin... 154 3e-36
UniRef50_Q5BKE9 Cluster: LOC594893 protein; n=5; Xenopus tropica... 152 1e-35
UniRef50_Q16K66 Cluster: Aldo-keto reductase; n=2; Aedes aegypti... 152 1e-35
UniRef50_Q6CFG7 Cluster: Yarrowia lipolytica chromosome B of str... 151 2e-35
UniRef50_Q7QK25 Cluster: ENSANGP00000019775; n=2; Anopheles gamb... 151 3e-35
UniRef50_A2QBD7 Cluster: Catalytic activity: an alcohol + NADP(+... 149 7e-35
UniRef50_Q23320 Cluster: Putative uncharacterized protein; n=4; ... 149 9e-35
UniRef50_A2EYY6 Cluster: Oxidoreductase, aldo/keto reductase fam... 148 2e-34
UniRef50_Q8SSK6 Cluster: ALDOSE REDUCTASE; n=1; Encephalitozoon ... 148 2e-34
UniRef50_Q96JD6 Cluster: Aldo-keto reductase family 1 member C-l... 95 3e-34
UniRef50_Q88SL1 Cluster: Oxidoreductase; n=51; Lactobacillales|R... 147 4e-34
UniRef50_Q0IBY6 Cluster: Alcohol dehydrogenase; n=2; Chroococcal... 147 4e-34
UniRef50_A2R6Z3 Cluster: Catalytic activity: an alcohol + NADP(+... 147 4e-34
UniRef50_A7CUW0 Cluster: 2,5-didehydrogluconate reductase; n=6; ... 146 7e-34
UniRef50_P14065 Cluster: Protein GCY; n=13; Saccharomycetales|Re... 146 7e-34
UniRef50_P51857 Cluster: 3-oxo-5-beta-steroid 4-dehydrogenase (E... 146 7e-34
UniRef50_UPI00015B40FA Cluster: PREDICTED: similar to CG2767-PA;... 145 2e-33
UniRef50_A7SIT3 Cluster: Predicted protein; n=1; Nematostella ve... 144 3e-33
UniRef50_Q5FK98 Cluster: Oxidoreductase; n=8; Lactobacillales|Re... 143 6e-33
UniRef50_P27800 Cluster: Aldehyde reductase 1; n=18; root|Rep: A... 143 6e-33
UniRef50_Q7ZWA4 Cluster: Zgc:56622; n=6; cellular organisms|Rep:... 142 1e-32
UniRef50_Q83N50 Cluster: 2,5-diketo-D-gluconic acid reductase; n... 142 1e-32
UniRef50_Q17G72 Cluster: Aldo-keto reductase; n=9; Endopterygota... 142 1e-32
UniRef50_Q5KI95 Cluster: Aldo-keto reductase, putative; n=14; Di... 142 1e-32
UniRef50_UPI0000519CC2 Cluster: PREDICTED: similar to CG2767-PA;... 141 2e-32
UniRef50_UPI0000498F1F Cluster: oxidoreductase, aldo/keto reduct... 141 2e-32
UniRef50_Q01J82 Cluster: OSIGBa0152K17.5 protein; n=28; Magnolio... 141 2e-32
UniRef50_A5KSS3 Cluster: Aldehyde reductase; n=1; candidate divi... 141 2e-32
UniRef50_UPI000023D0F1 Cluster: hypothetical protein FG03517.1; ... 140 4e-32
UniRef50_Q9VHX4 Cluster: CG2767-PA; n=4; Endopterygota|Rep: CG27... 140 6e-32
UniRef50_Q7ZA52 Cluster: Aldose reductase; n=6; Pezizomycotina|R... 140 6e-32
UniRef50_UPI0000E4A7CE Cluster: PREDICTED: similar to LOC553452 ... 138 1e-31
UniRef50_Q7G764 Cluster: Probable NAD(P)H-dependent oxidoreducta... 138 1e-31
UniRef50_Q55FL3 Cluster: Aldo-keto reductase; n=2; Dictyostelium... 138 2e-31
UniRef50_Q7PLK6 Cluster: CG40064-PA; n=1; Drosophila melanogaste... 138 2e-31
UniRef50_UPI00015B4912 Cluster: PREDICTED: similar to aldo-keto ... 137 3e-31
UniRef50_Q9U2J5 Cluster: Putative uncharacterized protein; n=2; ... 137 3e-31
UniRef50_P23901 Cluster: Aldose reductase; n=9; Poaceae|Rep: Ald... 137 3e-31
UniRef50_A3C1Z7 Cluster: Putative uncharacterized protein; n=2; ... 137 4e-31
UniRef50_Q01HB5 Cluster: OSIGBa0136O08-OSIGBa0153H12.9 protein; ... 136 5e-31
UniRef50_Q1YPE5 Cluster: Aldehyde reductase; n=7; Bacteria|Rep: ... 136 7e-31
UniRef50_P06632 Cluster: 2,5-diketo-D-gluconic acid reductase A;... 136 9e-31
UniRef50_Q03TW0 Cluster: Aldo/keto reductase of diketogulonate r... 135 1e-30
UniRef50_Q0PGJ6 Cluster: Aldo-keto reductase; n=32; Magnoliophyt... 135 1e-30
UniRef50_UPI0000E45E29 Cluster: PREDICTED: similar to aldose red... 134 3e-30
UniRef50_A1UEC5 Cluster: 2,5-didehydrogluconate reductase; n=20;... 134 3e-30
UniRef50_Q7QVQ9 Cluster: GLP_302_44328_45269; n=1; Giardia lambl... 134 3e-30
UniRef50_Q1U9L6 Cluster: 2,5-didehydrogluconate reductase; n=3; ... 133 7e-30
UniRef50_Q6RZX1 Cluster: Gld1; n=22; Pezizomycotina|Rep: Gld1 - ... 133 7e-30
UniRef50_Q7WSY4 Cluster: Putative aldo-keto reductase; n=1; Prop... 132 9e-30
UniRef50_Q7G765 Cluster: Probable NAD(P)H-dependent oxidoreducta... 132 9e-30
UniRef50_A7CWF9 Cluster: Aldehyde reductase; n=2; Bacteria|Rep: ... 132 1e-29
UniRef50_Q9FJK0 Cluster: Aldose reductase-like protein; n=3; cor... 132 1e-29
UniRef50_Q4PAT5 Cluster: Putative uncharacterized protein; n=1; ... 132 1e-29
UniRef50_Q22352 Cluster: Putative uncharacterized protein T08H10... 132 2e-29
UniRef50_A6RKL9 Cluster: Putative uncharacterized protein; n=3; ... 132 2e-29
UniRef50_A5VK30 Cluster: 2,5-didehydrogluconate reductase; n=2; ... 131 2e-29
UniRef50_A2EHN6 Cluster: Oxidoreductase, aldo/keto reductase fam... 131 2e-29
UniRef50_P28475 Cluster: NADP-dependent D-sorbitol-6-phosphate d... 130 4e-29
UniRef50_Q41E86 Cluster: 2,5-didehydrogluconate reductase; n=2; ... 130 6e-29
UniRef50_Q68ST9 Cluster: Reductase AKOR2; n=2; Pleurotus djamor|... 130 6e-29
UniRef50_Q890A0 Cluster: Oxidoreductase; n=6; Lactobacillales|Re... 129 8e-29
UniRef50_Q9HGY0 Cluster: Glycerol dehydrogenase; n=8; Saccharomy... 129 8e-29
UniRef50_Q7PM68 Cluster: ENSANGP00000014386; n=1; Anopheles gamb... 129 1e-28
UniRef50_A7PNI3 Cluster: Chromosome chr1 scaffold_22, whole geno... 128 1e-28
UniRef50_A2FPE2 Cluster: Oxidoreductase, aldo/keto reductase fam... 128 1e-28
UniRef50_Q10494 Cluster: Probable oxidoreductase C26F1.07; n=2; ... 128 1e-28
UniRef50_Q28P63 Cluster: Aldo/keto reductase; n=4; Rhodobacterac... 128 2e-28
UniRef50_P22045 Cluster: Probable reductase; n=101; cellular org... 128 2e-28
UniRef50_Q03PG5 Cluster: Aldo/keto reductase of diketogulonate r... 127 4e-28
UniRef50_A7BA05 Cluster: Putative uncharacterized protein; n=1; ... 127 4e-28
UniRef50_A1D4E3 Cluster: D-xylose reductase (Xyl1), putative; n=... 127 4e-28
UniRef50_Q9ZBW7 Cluster: Putative oxidoreductase; n=2; Actinomyc... 126 6e-28
UniRef50_Q0CLQ2 Cluster: Putative uncharacterized protein; n=1; ... 126 6e-28
UniRef50_Q96JD6-2 Cluster: Isoform 2 of Q96JD6 ; n=4; Catarrhini... 95 6e-28
UniRef50_A5PDA8 Cluster: Putative oxidoreductase protein; n=1; E... 126 8e-28
UniRef50_Q8G7K9 Cluster: Dehydrogenase or reductase protein; n=4... 126 1e-27
UniRef50_A2QVE5 Cluster: Similarity: shows similarity to several... 126 1e-27
UniRef50_Q2V420 Cluster: Uncharacterized protein At2g37770.1; n=... 125 2e-27
UniRef50_A3LTU8 Cluster: D-arabinose dehydrogenase; n=5; Sacchar... 125 2e-27
UniRef50_Q1VRG6 Cluster: YvgN; n=1; Psychroflexus torquis ATCC 7... 124 3e-27
UniRef50_A4RQH8 Cluster: Predicted protein; n=2; Ostreococcus|Re... 124 3e-27
UniRef50_Q568D7 Cluster: Zgc:110366; n=7; Euteleostomi|Rep: Zgc:... 124 4e-27
UniRef50_Q7N0E4 Cluster: 2,5-diketo-D-gluconic acid reductase A;... 123 5e-27
UniRef50_Q24C22 Cluster: Oxidoreductase, aldo/keto reductase fam... 123 5e-27
UniRef50_P38715 Cluster: NADPH-dependent aldose reductase GRE3; ... 123 5e-27
UniRef50_UPI0000DB6EE9 Cluster: PREDICTED: similar to C35D10.6; ... 123 7e-27
UniRef50_Q5HR31 Cluster: Oxidoreductase, aldo/keto reductase fam... 122 9e-27
UniRef50_Q1IN88 Cluster: Aldehyde reductase; n=5; Bacteria|Rep: ... 122 9e-27
UniRef50_A6ESC0 Cluster: ARA1; n=1; unidentified eubacterium SCB... 122 9e-27
UniRef50_Q4Q5N9 Cluster: Prostaglandin f synthase, putative; n=7... 122 9e-27
UniRef50_Q6C2L0 Cluster: Yarrowia lipolytica chromosome F of str... 122 9e-27
UniRef50_Q8ZI40 Cluster: 2,5-diketo-D-gluconic acid reductase A;... 122 9e-27
UniRef50_UPI0000499B0E Cluster: oxidoreductase, aldo/keto reduct... 121 2e-26
UniRef50_Q235V6 Cluster: Oxidoreductase, aldo/keto reductase fam... 121 3e-26
UniRef50_UPI0000D9A956 Cluster: PREDICTED: similar to aldo-keto ... 120 5e-26
UniRef50_Q8F1G4 Cluster: Aldehyde reductase; n=8; Bacteria|Rep: ... 120 5e-26
UniRef50_Q5FKI1 Cluster: Reductase-dehydrogenase; n=1; Lactobaci... 120 5e-26
UniRef50_A6W8E7 Cluster: 2,5-didehydrogluconate reductase; n=3; ... 120 5e-26
UniRef50_UPI00006CD296 Cluster: oxidoreductase, aldo/keto reduct... 120 7e-26
UniRef50_A7RRF6 Cluster: Predicted protein; n=2; Nematostella ve... 119 9e-26
UniRef50_A0JRJ3 Cluster: 2,5-didehydrogluconate reductase; n=3; ... 119 1e-25
UniRef50_Q8J0K1 Cluster: 4-dihydromethyltrisporate dehydrogenase... 119 1e-25
UniRef50_Q5TNP1 Cluster: ENSANGP00000029046; n=2; Culicidae|Rep:... 118 2e-25
UniRef50_Q9P6D3 Cluster: Related to aldo-keto reductase YPR1; n=... 118 2e-25
UniRef50_A2UAH0 Cluster: Aldo/keto reductase; n=1; Bacillus coag... 118 3e-25
UniRef50_Q8ET73 Cluster: 2,5-diketo-D-gluconate reductase; n=12;... 117 5e-25
UniRef50_Q7NB44 Cluster: ARA1; n=3; Firmicutes|Rep: ARA1 - Mycop... 117 5e-25
UniRef50_Q6U5V3 Cluster: Putative uncharacterized protein; n=1; ... 117 5e-25
UniRef50_Q18483 Cluster: Putative uncharacterized protein; n=2; ... 117 5e-25
UniRef50_P38115 Cluster: D-arabinose dehydrogenase [NAD(P)+] hea... 116 6e-25
UniRef50_Q5K8C5 Cluster: Aldo-keto reductase, putative; n=1; Fil... 116 8e-25
UniRef50_Q4JX70 Cluster: Putative oxidoreductase; n=1; Corynebac... 116 1e-24
UniRef50_Q4PDR0 Cluster: Putative uncharacterized protein; n=1; ... 115 1e-24
UniRef50_Q4P4P1 Cluster: Putative uncharacterized protein; n=1; ... 115 1e-24
UniRef50_Q15NA5 Cluster: Aldo/keto reductase; n=2; Gammaproteoba... 114 2e-24
UniRef50_Q838E0 Cluster: Oxidoreductase, aldo/keto reductase fam... 114 3e-24
UniRef50_Q043M4 Cluster: Aldo/keto reductase of diketogulonate r... 114 3e-24
UniRef50_P47137 Cluster: Probable oxidoreductase YJR096W; n=8; S... 114 3e-24
UniRef50_Q5BLA6 Cluster: Zgc:110782; n=2; Danio rerio|Rep: Zgc:1... 113 6e-24
UniRef50_A0JRJ6 Cluster: Aldo/keto reductase; n=2; Micrococcinea... 113 6e-24
UniRef50_Q76L37 Cluster: Conjugated polyketone reductase C1; n=3... 113 6e-24
UniRef50_A6NPD6 Cluster: Putative uncharacterized protein; n=3; ... 113 8e-24
UniRef50_Q6CEJ0 Cluster: Yarrowia lipolytica chromosome B of str... 113 8e-24
UniRef50_A2QL02 Cluster: Putative frameshift; n=1; Aspergillus n... 113 8e-24
UniRef50_P15339 Cluster: 2,5-diketo-D-gluconic acid reductase B;... 113 8e-24
UniRef50_A0AWM8 Cluster: Aldo/keto reductase; n=4; Actinomycetal... 112 1e-23
UniRef50_Q2U219 Cluster: Aldo/keto reductase family proteins; n=... 112 1e-23
UniRef50_Q9X0A2 Cluster: Oxidoreductase, aldo/keto reductase fam... 111 2e-23
UniRef50_Q9ZUJ6 Cluster: T2K10.1 protein; n=16; core eudicotyled... 111 2e-23
UniRef50_UPI00015B5BD7 Cluster: PREDICTED: similar to aldo-keto ... 111 2e-23
UniRef50_Q07551 Cluster: NADPH-dependent alpha-keto amide reduct... 111 2e-23
UniRef50_Q7VG53 Cluster: Aldo-keto reductase; n=28; Bacteria|Rep... 111 3e-23
UniRef50_Q1Q8W8 Cluster: Aldo/keto reductase; n=1; Psychrobacter... 111 3e-23
UniRef50_Q5T2L2 Cluster: Aldo-keto reductase family 1 member C-l... 111 3e-23
UniRef50_Q9X265 Cluster: Oxidoreductase, aldo/keto reductase fam... 110 4e-23
UniRef50_Q05KR9 Cluster: Benzil reductase; n=5; Bacillales|Rep: ... 110 4e-23
UniRef50_Q03XK0 Cluster: Aldo/keto reductase of diketogulonate r... 110 4e-23
UniRef50_A6WDZ5 Cluster: Aldo/keto reductase; n=5; Bacteria|Rep:... 110 4e-23
UniRef50_A5ZYE6 Cluster: Putative uncharacterized protein; n=1; ... 110 4e-23
UniRef50_UPI00006CCCD7 Cluster: oxidoreductase, aldo/keto reduct... 110 5e-23
UniRef50_Q3E9M9 Cluster: Uncharacterized protein At5g01670.2; n=... 110 5e-23
UniRef50_Q8ZH36 Cluster: 2,5-diketo-D-gluconic acid reductase B;... 110 5e-23
UniRef50_Q88TV9 Cluster: Oxidoreductase; n=4; Lactobacillus|Rep:... 109 7e-23
UniRef50_A3LWP0 Cluster: Aldo/keto reductase; n=7; Saccharomycet... 109 7e-23
UniRef50_Q6NII7 Cluster: Putative oxidoreductase; n=2; Corynebac... 109 9e-23
UniRef50_Q4PHK0 Cluster: Putative uncharacterized protein; n=1; ... 109 9e-23
UniRef50_Q75E75 Cluster: ABL209Cp; n=1; Eremothecium gossypii|Re... 108 2e-22
UniRef50_Q03U37 Cluster: Aldo/keto reductase of diketogulonate r... 108 2e-22
UniRef50_Q7R2T6 Cluster: GLP_291_56367_57278; n=1; Giardia lambl... 108 2e-22
UniRef50_A3JU52 Cluster: 2,5-diketo-D-gluconic acid reductase A;... 107 3e-22
UniRef50_A0JX62 Cluster: 2,5-didehydrogluconate reductase; n=9; ... 107 5e-22
UniRef50_Q5FT75 Cluster: Putative 2,5-diketo-D-gluconic acid red... 106 7e-22
UniRef50_Q89JN4 Cluster: Oxidoreductase; n=8; Rhizobiales|Rep: O... 106 9e-22
UniRef50_A0L1A2 Cluster: Aldo/keto reductase; n=8; Gammaproteoba... 105 2e-21
UniRef50_Q17DN1 Cluster: Aldo-keto reductase; n=1; Aedes aegypti... 105 2e-21
UniRef50_Q6F7K7 Cluster: 2,5-diketo-D-gluconate reductase; n=20;... 105 2e-21
UniRef50_Q0CK00 Cluster: Predicted protein; n=1; Aspergillus ter... 105 2e-21
UniRef50_Q927P9 Cluster: Lin2739 protein; n=12; Bacteria|Rep: Li... 104 3e-21
UniRef50_A3VRL4 Cluster: Putative uncharacterized protein; n=1; ... 103 5e-21
UniRef50_O13848 Cluster: NADH/NADPH dependent indole-3-acetaldeh... 103 6e-21
UniRef50_Q4V008 Cluster: Oxidoreductase; n=4; Proteobacteria|Rep... 103 8e-21
UniRef50_Q0SFM4 Cluster: Probable 2,5-didehydrogluconate reducta... 103 8e-21
UniRef50_Q5XJM7 Cluster: Zgc:101765; n=5; Eumetazoa|Rep: Zgc:101... 102 1e-20
UniRef50_Q929C8 Cluster: Lin2349 protein; n=12; Listeria|Rep: Li... 102 1e-20
UniRef50_A7SGW6 Cluster: Predicted protein; n=1; Nematostella ve... 102 1e-20
UniRef50_Q8Y463 Cluster: Lmo2592 protein; n=40; Bacteria|Rep: Lm... 101 2e-20
UniRef50_Q1M4Z6 Cluster: Putative aldo-keto reductase/oxidase; n... 101 2e-20
UniRef50_A2QB88 Cluster: Contig An01c0460, complete genome. prec... 101 2e-20
UniRef50_Q5UX52 Cluster: Oxidoreductase aldo/keto reductase fami... 101 2e-20
UniRef50_Q927E1 Cluster: Lin2848 protein; n=13; Listeria|Rep: Li... 101 3e-20
UniRef50_Q7XY49 Cluster: Mannose 6-phosphate reductase; n=1; Gri... 91 3e-20
UniRef50_A7TLC4 Cluster: Putative uncharacterized protein; n=1; ... 100 6e-20
UniRef50_Q02198 Cluster: Morphine 6-dehydrogenase; n=5; Bacteria... 100 6e-20
UniRef50_Q5FK99 Cluster: Oxidoreductase aldo-keto reductase fami... 99 8e-20
UniRef50_Q1RFP0 Cluster: 2,5-diketo-D-gluconic acid reductase A;... 99 8e-20
UniRef50_UPI0000D56CE5 Cluster: PREDICTED: similar to CG6084-PA,... 100 1e-19
UniRef50_UPI00006CA3CB Cluster: oxidoreductase, aldo/keto reduct... 100 1e-19
UniRef50_P70883 Cluster: AkrI; n=1; Butyrivibrio fibrisolvens|Re... 100 1e-19
UniRef50_A3VHZ9 Cluster: Oxidoreductase; n=1; Rhodobacterales ba... 100 1e-19
UniRef50_A2RMU6 Cluster: Oxidoreductase, aldo/keto reductase fam... 100 1e-19
UniRef50_A7BES9 Cluster: Putative uncharacterized protein; n=1; ... 99 1e-19
UniRef50_A6LZ55 Cluster: 2,5-didehydrogluconate reductase; n=1; ... 99 1e-19
UniRef50_Q11B35 Cluster: Aldo/keto reductase; n=1; Mesorhizobium... 99 2e-19
UniRef50_Q1DLF1 Cluster: Putative uncharacterized protein; n=1; ... 99 2e-19
UniRef50_A3UJS6 Cluster: Oxidoreductase; n=3; Alphaproteobacteri... 98 3e-19
UniRef50_Q9HM42 Cluster: Alcohol dehydrogenase related protein; ... 98 3e-19
UniRef50_A7D6Q0 Cluster: Aldo/keto reductase; n=1; Halorubrum la... 98 3e-19
UniRef50_Q54NR2 Cluster: Aldo-keto reductase; n=3; Dictyostelium... 97 4e-19
UniRef50_A7P424 Cluster: Chromosome chr1 scaffold_5, whole genom... 97 5e-19
UniRef50_Q76L36 Cluster: Conjugated polyketone reductase C2; n=1... 97 5e-19
UniRef50_Q5V398 Cluster: Oxidoreductase aldo/keto reductase fami... 97 5e-19
UniRef50_Q14LA8 Cluster: Putative aldo/keto reductase oxidoreduc... 97 7e-19
UniRef50_Q03BE0 Cluster: Aldo/keto reductase family enzyme; n=5;... 97 7e-19
UniRef50_A7ALH6 Cluster: Putative uncharacterized protein; n=1; ... 97 7e-19
UniRef50_A6PR52 Cluster: Aldo/keto reductase; n=1; Victivallis v... 97 7e-19
UniRef50_Q4FY75 Cluster: Aldo-keto reductase-like protein; n=5; ... 97 7e-19
UniRef50_A6VNW9 Cluster: Aldo/keto reductase precursor; n=1; Act... 96 9e-19
UniRef50_Q5V663 Cluster: Aldehyde reductase; n=6; Halobacteriace... 96 9e-19
UniRef50_Q979I4 Cluster: Aldo / keto reductase; n=3; Archaea|Rep... 96 1e-18
UniRef50_Q11BF8 Cluster: Aldo/keto reductase; n=12; Bacteria|Rep... 95 2e-18
UniRef50_Q572D2 Cluster: Aldo-keto reductase, putative; n=1; Phy... 95 2e-18
UniRef50_Q5V6N9 Cluster: Alcohol dehydrogenase; n=2; Halobacteri... 95 2e-18
UniRef50_Q8DK16 Cluster: Tlr1054 protein; n=6; Cyanobacteria|Rep... 95 3e-18
UniRef50_Q1PV10 Cluster: Putative uncharacterized protein; n=1; ... 94 4e-18
UniRef50_Q5KKZ8 Cluster: Aldo-keto reductase, putative; n=2; Fil... 94 4e-18
UniRef50_A5DRJ6 Cluster: Putative uncharacterized protein; n=4; ... 94 4e-18
UniRef50_Q4P1G1 Cluster: Putative uncharacterized protein; n=1; ... 94 5e-18
UniRef50_A4YQ04 Cluster: 2,5-diketo-D-gluconate reductase B; n=1... 93 7e-18
UniRef50_Q09632 Cluster: Probable oxidoreductase ZK1290.5; n=2; ... 93 7e-18
UniRef50_UPI000155CAC7 Cluster: PREDICTED: hypothetical protein;... 93 9e-18
UniRef50_A6RMS0 Cluster: Putative uncharacterized protein; n=1; ... 93 9e-18
UniRef50_Q3CZS2 Cluster: Oxidoreductase, aldo/keto reductase fam... 92 2e-17
UniRef50_Q4WUF7 Cluster: Aldo-keto reductase, putative; n=3; Pez... 92 2e-17
UniRef50_Q5NLW3 Cluster: Putative oxidoreductase; n=1; Zymomonas... 92 2e-17
UniRef50_A4FEB9 Cluster: 2,5-diketo-D-gluconic acid reductase; n... 91 3e-17
UniRef50_P91997 Cluster: Putative uncharacterized protein; n=4; ... 91 3e-17
UniRef50_A1RB46 Cluster: 2,5-diketo-D-gluconate reductase; n=1; ... 91 3e-17
UniRef50_O14088 Cluster: Xylose and arabinose reductase; n=1; Sc... 91 3e-17
UniRef50_Q9C1X5 Cluster: Xylose and arabinose reductase; n=1; Sc... 91 5e-17
UniRef50_Q59ZT1 Cluster: Putative uncharacterized protein; n=1; ... 91 5e-17
UniRef50_Q00XM4 Cluster: Aldo/keto reductase family proteins; n=... 90 8e-17
UniRef50_Q5UYI9 Cluster: Oxidoreductase; n=1; Haloarcula marismo... 90 8e-17
UniRef50_A7D7K7 Cluster: Aldo/keto reductase; n=1; Halorubrum la... 90 8e-17
UniRef50_Q21274 Cluster: Putative uncharacterized protein; n=1; ... 89 1e-16
UniRef50_Q4WI64 Cluster: Aldehyde reductase, putative; n=22; Pez... 89 1e-16
UniRef50_A1CAM7 Cluster: Aldo-keto reductase, putative; n=9; Dik... 89 1e-16
UniRef50_Q7VHE1 Cluster: Putative uncharacterized protein; n=1; ... 89 1e-16
UniRef50_Q97U17 Cluster: Oxidoreductase, aldo/keto reductase fam... 89 2e-16
UniRef50_Q6L139 Cluster: 2,5-diketo-D-gluconic acid reductase; n... 89 2e-16
UniRef50_Q4JCC1 Cluster: 2,5-diketo-D-gluconic acid reductase A;... 89 2e-16
UniRef50_Q17568 Cluster: Putative uncharacterized protein; n=1; ... 88 2e-16
UniRef50_Q2BBN7 Cluster: YvgN; n=1; Bacillus sp. NRRL B-14911|Re... 88 3e-16
UniRef50_Q11DV1 Cluster: Aldo/keto reductase; n=10; Alphaproteob... 88 3e-16
UniRef50_A7D6I8 Cluster: Aldo/keto reductase; n=1; Halorubrum la... 87 4e-16
UniRef50_Q5FLI5 Cluster: Aldehyde reductase; n=2; Bacteria|Rep: ... 87 6e-16
UniRef50_A7RUA2 Cluster: Predicted protein; n=1; Nematostella ve... 87 6e-16
UniRef50_Q2H7A8 Cluster: Putative uncharacterized protein; n=1; ... 87 6e-16
UniRef50_A4IJ00 Cluster: LOC548351 protein; n=1; Xenopus tropica... 67 7e-16
UniRef50_Q68A33 Cluster: Aldo-keto reductase 1a; n=1; Ciona inte... 87 7e-16
UniRef50_Q9P734 Cluster: Related to 2, 5-diketo-D-gluconic acid ... 87 7e-16
UniRef50_Q2CAL9 Cluster: 2,5-didehydrogluconate reductase; n=2; ... 86 1e-15
UniRef50_Q9A2X8 Cluster: Oxidoreductase, aldo/keto reductase fam... 85 2e-15
UniRef50_Q9V2P1 Cluster: Myo-inositol degradation; n=5; Archaea|... 85 2e-15
UniRef50_UPI000023DF27 Cluster: hypothetical protein FG07276.1; ... 85 3e-15
UniRef50_Q6WGK4 Cluster: Aldose reductase; n=1; Pristionchus pac... 85 3e-15
UniRef50_Q5KCN9 Cluster: Putative uncharacterized protein; n=1; ... 85 3e-15
UniRef50_Q8EUH6 Cluster: Oxidoreductase; n=1; Mycoplasma penetra... 84 4e-15
UniRef50_Q4DJ59 Cluster: Aldo/keto reductase, putative; n=2; Try... 84 4e-15
UniRef50_Q03X85 Cluster: Aldo/keto reductase of diketogulonate r... 83 7e-15
UniRef50_A3WP89 Cluster: Aldo/keto reductase; n=1; Idiomarina ba... 81 3e-14
UniRef50_A3T261 Cluster: Putative uncharacterized protein; n=1; ... 79 1e-13
UniRef50_Q9USV2 Cluster: Xylose and arabinose reductase; n=2; Sc... 79 2e-13
UniRef50_Q8EVT8 Cluster: Oxidoreductase-aldo/keto reductase fami... 79 2e-13
UniRef50_Q59Z55 Cluster: Potential aldo/keto reductase; n=6; Sac... 78 3e-13
UniRef50_Q16CS5 Cluster: 2,5-diketo-D-gluconic acid reductase B,... 78 3e-13
UniRef50_Q5B5R6 Cluster: Putative uncharacterized protein; n=1; ... 78 3e-13
UniRef50_UPI000038E317 Cluster: hypothetical protein Faci_030017... 77 5e-13
UniRef50_A0LJ47 Cluster: Aldo/keto reductase; n=1; Syntrophobact... 77 5e-13
UniRef50_Q5KD52 Cluster: Oxidoreductase, putative; n=1; Filobasi... 77 5e-13
UniRef50_Q14LU6 Cluster: Putative aldo/keto reductase oxidoreduc... 77 6e-13
UniRef50_A6SI80 Cluster: Putative uncharacterized protein; n=1; ... 77 8e-13
UniRef50_Q5V1M9 Cluster: Oxidoreductase aldo/keto reductase fami... 77 8e-13
UniRef50_Q013C5 Cluster: Glycerol dehydrogenase, putative; n=2; ... 76 1e-12
UniRef50_Q4WP69 Cluster: Aldehyde reductase, putative; n=1; Aspe... 76 1e-12
UniRef50_Q89RG2 Cluster: Aldo/keto reductase; n=11; Bacteria|Rep... 76 1e-12
UniRef50_Q7M4N1 Cluster: Dihydrodiol dehydrogenase DD2; n=2; Hom... 75 2e-12
UniRef50_A7D761 Cluster: Aldo/keto reductase; n=2; Halobacteriac... 75 2e-12
UniRef50_A2G4I3 Cluster: Oxidoreductase, aldo/keto reductase fam... 75 2e-12
UniRef50_Q5KPU6 Cluster: Putative uncharacterized protein; n=2; ... 75 3e-12
UniRef50_Q8EUX1 Cluster: Aldo/keto reductase family oxidoreducta... 74 4e-12
UniRef50_A3DNU7 Cluster: Aldo/keto reductase; n=3; Desulfurococc... 74 6e-12
UniRef50_Q7NK63 Cluster: Gll1617 protein; n=1; Gloeobacter viola... 73 1e-11
UniRef50_Q4PE96 Cluster: Putative uncharacterized protein; n=1; ... 73 1e-11
UniRef50_Q1IQ78 Cluster: Aldo/keto reductase; n=1; Acidobacteria... 73 1e-11
UniRef50_Q5KKC5 Cluster: Putative uncharacterized protein; n=2; ... 72 2e-11
UniRef50_Q8EVS8 Cluster: Oxidoreductase; n=1; Mycoplasma penetra... 71 4e-11
UniRef50_A1CHK2 Cluster: Aldose 1-epimerase, putative; n=11; Pez... 71 4e-11
UniRef50_A5BF24 Cluster: Putative uncharacterized protein; n=1; ... 71 5e-11
UniRef50_Q04TM6 Cluster: Aryl-alcohol dehydrogenase-related oxid... 69 1e-10
UniRef50_A5V463 Cluster: Aldo/keto reductase; n=1; Sphingomonas ... 69 2e-10
UniRef50_Q97UV9 Cluster: Oxidoreductase; n=1; Sulfolobus solfata... 69 2e-10
UniRef50_Q4Q5X1 Cluster: Aldehyde reductase, putative; n=75; cel... 68 4e-10
UniRef50_Q6CWB9 Cluster: Similarities with sp|Q12458 Saccharomyc... 68 4e-10
UniRef50_P76234 Cluster: Uncharacterized protein yeaE; n=39; Bac... 68 4e-10
UniRef50_A3H9Y8 Cluster: Aldo/keto reductase; n=2; Caldivirga ma... 67 5e-10
UniRef50_A7HEV1 Cluster: Aldo/keto reductase; n=13; Bacteria|Rep... 66 9e-10
UniRef50_Q6NKP1 Cluster: At5g53580; n=18; cellular organisms|Rep... 66 9e-10
UniRef50_UPI0000DAE567 Cluster: hypothetical protein Rgryl_01000... 66 1e-09
UniRef50_Q5FHT2 Cluster: Aldehyde reductase; n=4; Lactobacillus|... 66 1e-09
UniRef50_Q3ZWR6 Cluster: Oxidoreductase, aldo reductase; n=3; De... 66 1e-09
UniRef50_Q97V56 Cluster: Dehydrogenase; n=8; Thermoprotei|Rep: D... 66 1e-09
UniRef50_P80874 Cluster: General stress protein 69; n=16; cellul... 66 1e-09
UniRef50_Q64W37 Cluster: 2,5-diketo-D-gluconic acid reductase; n... 65 2e-09
UniRef50_Q8YXI8 Cluster: All1225 protein; n=9; Cyanobacteria|Rep... 65 3e-09
UniRef50_A4M6J9 Cluster: Aldo/keto reductase; n=1; Petrotoga mob... 65 3e-09
UniRef50_A5AD50 Cluster: Putative uncharacterized protein; n=3; ... 65 3e-09
UniRef50_Q61U89 Cluster: Putative uncharacterized protein CBG054... 65 3e-09
UniRef50_Q1EZH4 Cluster: Aldo/keto reductase:4Fe-4S ferredoxin, ... 64 3e-09
UniRef50_A6QXT4 Cluster: Predicted protein; n=1; Ajellomyces cap... 64 3e-09
UniRef50_A7LSN6 Cluster: Putative uncharacterized protein; n=3; ... 64 5e-09
UniRef50_Q391C9 Cluster: Aldo/keto reductase; n=10; Proteobacter... 64 6e-09
UniRef50_Q0GU15 Cluster: ORF28; n=3; Bacteria|Rep: ORF28 - Lacto... 64 6e-09
UniRef50_Q8ZU65 Cluster: Aldo-keto reductase, putative; n=4; The... 64 6e-09
UniRef50_Q5B034 Cluster: Putative uncharacterized protein; n=1; ... 63 8e-09
UniRef50_A7EW94 Cluster: Putative uncharacterized protein; n=1; ... 63 8e-09
UniRef50_Q21EY6 Cluster: Aldo/keto reductase; n=1; Saccharophagu... 62 1e-08
UniRef50_Q6CGE9 Cluster: Similar to sp|P47137 Saccharomyces cere... 62 1e-08
UniRef50_Q94A68 Cluster: Uncharacterized oxidoreductase At1g0669... 62 1e-08
UniRef50_UPI00005F9591 Cluster: COG0656: Aldo/keto reductases, r... 62 2e-08
UniRef50_Q88TP1 Cluster: Oxidoreductase; n=3; Bacteria|Rep: Oxid... 62 2e-08
UniRef50_UPI00015BB020 Cluster: aldo/keto reductase; n=1; Ignico... 62 2e-08
UniRef50_Q8EVP7 Cluster: Putative oxidoreductase; n=3; Bacteria|... 62 2e-08
UniRef50_Q18903 Cluster: Putative uncharacterized protein C56G3.... 61 3e-08
UniRef50_A6R5B4 Cluster: NAD(P)H-dependent D-xylose reductase; n... 61 3e-08
UniRef50_A6QVW8 Cluster: Predicted protein; n=1; Ajellomyces cap... 61 3e-08
UniRef50_Q4Q973 Cluster: Aldo/keto reductase, putative; n=3; Lei... 60 6e-08
UniRef50_Q09923 Cluster: Aldo-keto reductase yakc [NADP+]; n=13;... 60 6e-08
UniRef50_Q54CX8 Cluster: Putative uncharacterized protein; n=1; ... 60 1e-07
UniRef50_A1S0T5 Cluster: Aldo/keto reductase; n=2; Thermoprotei|... 59 1e-07
UniRef50_Q8PN61 Cluster: Oxidoreductase; n=5; Proteobacteria|Rep... 59 2e-07
UniRef50_Q55493 Cluster: Auxin-induced protein; n=2; Bacteria|Re... 59 2e-07
UniRef50_A2UBC7 Cluster: Aldo/keto reductase; n=3; cellular orga... 59 2e-07
UniRef50_A4R217 Cluster: Putative uncharacterized protein; n=1; ... 59 2e-07
UniRef50_Q31SB1 Cluster: Putative uncharacterized protein; n=2; ... 58 3e-07
UniRef50_A6C9W8 Cluster: Aldo/keto reductase; n=2; Planctomyceta... 58 3e-07
UniRef50_Q8Y5Q1 Cluster: Lmo2005 protein; n=34; cellular organis... 57 7e-07
UniRef50_Q60BI7 Cluster: Oxidoreductase, aldo/keto reductase fam... 56 9e-07
UniRef50_Q5ZTU6 Cluster: D-xylose reductase III; n=5; Legionella... 56 9e-07
UniRef50_Q1VSU3 Cluster: Aryl-alcohol dehydrogenase; n=1; Psychr... 56 9e-07
UniRef50_A6BIJ0 Cluster: Putative uncharacterized protein; n=1; ... 56 9e-07
UniRef50_Q660Z5 Cluster: Aldose reductase, putative; n=3; Borrel... 56 1e-06
UniRef50_Q64UK5 Cluster: Aldo/keto reductase family oxidoreducta... 56 2e-06
UniRef50_Q97UJ7 Cluster: Oxidoreductase; n=4; Archaea|Rep: Oxido... 56 2e-06
UniRef50_P46905 Cluster: Uncharacterized oxidoreductase yccK; n=... 56 2e-06
UniRef50_Q31DD1 Cluster: Aldo/keto reductase family; n=5; Prochl... 55 2e-06
UniRef50_A1SLH1 Cluster: Aldo/keto reductase; n=27; Bacteria|Rep... 55 2e-06
UniRef50_Q46851 Cluster: Uncharacterized protein yghZ; n=126; Ba... 55 2e-06
UniRef50_Q3WEJ4 Cluster: Aldo/keto reductase; n=9; Bacteria|Rep:... 55 3e-06
UniRef50_A6VXX8 Cluster: Aldo/keto reductase; n=2; Marinomonas|R... 55 3e-06
UniRef50_Q55FL2 Cluster: Putative uncharacterized protein; n=1; ... 55 3e-06
UniRef50_P82125 Cluster: 1,5-anhydro-D-fructose reductase; n=1; ... 55 3e-06
UniRef50_A7BLU0 Cluster: Aldo/keto reductase family; n=1; Beggia... 54 4e-06
UniRef50_P91021 Cluster: Putative uncharacterized protein; n=1; ... 54 4e-06
UniRef50_A7RXR1 Cluster: Predicted protein; n=3; Eumetazoa|Rep: ... 54 4e-06
UniRef50_Q2NGB6 Cluster: Predicted oxidoreductase; n=1; Methanos... 54 4e-06
UniRef50_Q2J8X9 Cluster: Aldo/keto reductase; n=3; Frankia|Rep: ... 54 5e-06
UniRef50_Q55ML8 Cluster: Putative uncharacterized protein; n=2; ... 54 6e-06
UniRef50_Q2H1Q3 Cluster: Putative uncharacterized protein; n=1; ... 54 6e-06
UniRef50_Q0TYC7 Cluster: Predicted protein; n=1; Phaeosphaeria n... 54 6e-06
UniRef50_A4RPC9 Cluster: Putative uncharacterized protein; n=1; ... 54 6e-06
UniRef50_A6X3I0 Cluster: Aldo/keto reductase; n=3; Bacteria|Rep:... 53 9e-06
UniRef50_A6RYK4 Cluster: Putative uncharacterized protein; n=1; ... 53 9e-06
UniRef50_A7AFQ7 Cluster: Putative uncharacterized protein; n=1; ... 53 1e-05
UniRef50_Q9W2X0 Cluster: CG32688-PA, isoform A; n=4; Sophophora|... 53 1e-05
UniRef50_P77256 Cluster: Uncharacterized oxidoreductase ydjG; n=... 53 1e-05
UniRef50_UPI00005A2CCB Cluster: PREDICTED: similar to Aldose red... 52 1e-05
UniRef50_Q81RN9 Cluster: Oxidoreductase, aldo/keto reductase fam... 52 1e-05
UniRef50_A6FYX9 Cluster: Oxidoreductase; n=1; Plesiocystis pacif... 52 1e-05
UniRef50_A5CYR4 Cluster: Predicted oxidoreductases; n=2; Clostri... 52 1e-05
UniRef50_A4CIJ8 Cluster: Putative uncharacterized protein; n=2; ... 52 3e-05
UniRef50_A7RPK2 Cluster: Predicted protein; n=1; Nematostella ve... 52 3e-05
UniRef50_Q0CV71 Cluster: Putative uncharacterized protein; n=2; ... 52 3e-05
UniRef50_A0RYR0 Cluster: Oxidoreductase; n=2; cellular organisms... 52 3e-05
UniRef50_Q38Z15 Cluster: Putative aldo/keto reductase; n=2; Bact... 51 5e-05
UniRef50_Q1FEK2 Cluster: Aldo/keto reductase:4Fe-4S ferredoxin, ... 51 5e-05
UniRef50_Q03I00 Cluster: Aryl-alcohol dehydrogenase related enzy... 51 5e-05
UniRef50_Q1FGT1 Cluster: Aldo/keto reductase:4Fe-4S ferredoxin, ... 50 6e-05
UniRef50_A3U5K6 Cluster: Oxidoreductase, aldo/keto reductase fam... 50 6e-05
UniRef50_A5BYJ4 Cluster: Putative uncharacterized protein; n=1; ... 50 6e-05
UniRef50_Q4WF80 Cluster: Glycerol dehydrogenase (GCY1), putative... 50 6e-05
UniRef50_Q1GHE2 Cluster: Aldo/keto reductase; n=8; Alphaproteoba... 50 8e-05
UniRef50_A1RA11 Cluster: Oxidoreductase, aldo/keto reductase fam... 50 8e-05
UniRef50_Q27ST7 Cluster: Oxidoreductase; n=2; Eukaryota|Rep: Oxi... 50 8e-05
UniRef50_Q4WE75 Cluster: Aldehyde reductase (GliO), putative; n=... 50 8e-05
UniRef50_Q2BBT9 Cluster: Probable oxidoreductase protein; n=2; B... 50 1e-04
UniRef50_Q0DHN0 Cluster: Os05g0456200 protein; n=2; Oryza sativa... 50 1e-04
UniRef50_UPI00003C85A8 Cluster: hypothetical protein Faci_030001... 49 1e-04
UniRef50_Q03UP2 Cluster: Aryl-alcohol dehydrogenase family enzym... 49 1e-04
UniRef50_A7HL79 Cluster: Aldo/keto reductase; n=1; Fervidobacter... 49 1e-04
UniRef50_A0QHX8 Cluster: General stress protein 69; n=2; Mycobac... 49 1e-04
UniRef50_A7PNT1 Cluster: Chromosome chr8 scaffold_23, whole geno... 49 1e-04
UniRef50_Q93KW0 Cluster: Putative oxidoreductase; n=1; Streptomy... 49 2e-04
UniRef50_A0Q648 Cluster: Aldo/keto reductase family protein; n=1... 49 2e-04
UniRef50_A7T149 Cluster: Predicted protein; n=1; Nematostella ve... 49 2e-04
UniRef50_A6XQ31 Cluster: Putative uncharacterized protein; n=1; ... 49 2e-04
UniRef50_Q97UG6 Cluster: Oxidoreductase; n=5; Archaea|Rep: Oxido... 49 2e-04
UniRef50_UPI0000DB6B5C Cluster: PREDICTED: similar to glutamate-... 48 2e-04
UniRef50_Q0B0F0 Cluster: Oxidoreductase; n=1; Syntrophomonas wol... 48 2e-04
UniRef50_A7B2Y7 Cluster: Putative uncharacterized protein; n=1; ... 48 2e-04
UniRef50_A4AP98 Cluster: Putative uncharacterized protein; n=1; ... 48 2e-04
UniRef50_Q5KYH6 Cluster: K+ channel beta subunit; n=5; Bacteria|... 48 3e-04
UniRef50_A6CMV7 Cluster: Putative uncharacterized protein; n=2; ... 48 3e-04
UniRef50_Q88ZU3 Cluster: Oxidoreductase; n=1; Lactobacillus plan... 48 4e-04
UniRef50_Q1U6R9 Cluster: Aldo/keto reductase; n=25; Bacilli|Rep:... 48 4e-04
UniRef50_Q9X0R5 Cluster: Oxidoreductase, aldo/keto reductase fam... 47 6e-04
UniRef50_A6SUJ2 Cluster: Uncharacterized conserved protein; n=2;... 47 6e-04
UniRef50_A3K469 Cluster: Aldo/keto reductase; n=3; Rhodobacterac... 47 6e-04
UniRef50_Q7Q0Y6 Cluster: ENSANGP00000006086; n=7; Coelomata|Rep:... 47 6e-04
UniRef50_Q2NFN7 Cluster: Predicted oxidoreductase; n=1; Methanos... 47 6e-04
UniRef50_Q67NQ1 Cluster: Oxidoreductase; n=1; Symbiobacterium th... 47 7e-04
UniRef50_Q08NK7 Cluster: Aldo/keto reductase; n=1; Stigmatella a... 47 7e-04
UniRef50_A7GIW7 Cluster: Oxidoreductase, aldo/keto reductase fam... 47 7e-04
UniRef50_Q5ASJ7 Cluster: Putative uncharacterized protein; n=1; ... 47 7e-04
UniRef50_Q97ZZ1 Cluster: Oxidoreductase; n=4; Sulfolobaceae|Rep:... 47 7e-04
UniRef50_Q8R6G2 Cluster: Oxidoreductase; n=1; Fusobacterium nucl... 46 0.001
UniRef50_Q5ZRR0 Cluster: Aldo/keto reductase; n=3; Legionella pn... 46 0.001
UniRef50_Q7D3N9 Cluster: AGR_pAT_274p; n=3; Proteobacteria|Rep: ... 46 0.001
UniRef50_A1VNV6 Cluster: Aldo/keto reductase precursor; n=7; Pro... 46 0.001
UniRef50_Q87SA8 Cluster: Oxidoreductase Tas, aldo/keto reductase... 46 0.001
UniRef50_Q0LP88 Cluster: Aldo/keto reductase; n=4; Bacteria|Rep:... 46 0.001
UniRef50_Q034L5 Cluster: Aryl-alcohol dehydrogenase related enzy... 46 0.001
UniRef50_A4A767 Cluster: Aldo/keto reductase/Endoribonuclease L-... 46 0.001
UniRef50_A0K203 Cluster: Aldo/keto reductase; n=2; Arthrobacter|... 46 0.001
UniRef50_P42972 Cluster: Uncharacterized oxidoreductase ycsN; n=... 46 0.001
UniRef50_A5EX65 Cluster: Aldo/keto reductase family protein; n=1... 46 0.002
UniRef50_A1SY15 Cluster: Aldo/keto reductase; n=1; Psychromonas ... 46 0.002
UniRef50_A0ZZJ3 Cluster: Oxidoreductase; n=2; Bifidobacterium ad... 46 0.002
UniRef50_A0LHW7 Cluster: Aldo/keto reductase precursor; n=1; Syn... 46 0.002
UniRef50_A0JVH3 Cluster: Aldo/keto reductase; n=17; Bacteria|Rep... 46 0.002
UniRef50_Q00T51 Cluster: Aldo/keto reductase; n=2; Ostreococcus|... 46 0.002
UniRef50_O43448 Cluster: Voltage-gated potassium channel subunit... 46 0.002
UniRef50_Q2JHT1 Cluster: Aldo/keto reductase Tas; n=25; cellular... 45 0.002
UniRef50_Q8VV02 Cluster: Putative oxidoreductase; n=1; Streptomy... 45 0.002
UniRef50_A6W292 Cluster: Aldo/keto reductase; n=9; Bacteria|Rep:... 45 0.002
UniRef50_A6LWU9 Cluster: Aldo/keto reductase; n=3; Clostridium|R... 45 0.002
UniRef50_A6C2P2 Cluster: Oxidoreductase, aldo/keto reductase fam... 45 0.002
UniRef50_A4MAE7 Cluster: Aldo/keto reductase; n=1; Petrotoga mob... 45 0.002
UniRef50_P73573 Cluster: Sll0867 protein; n=15; Bacteria|Rep: Sl... 45 0.003
UniRef50_Q13GB1 Cluster: Aldo/keto reductase; n=1; Burkholderia ... 45 0.003
UniRef50_A5VEK4 Cluster: Aldo/keto reductase; n=5; Bacteria|Rep:... 45 0.003
UniRef50_A5FZX7 Cluster: Aldo/keto reductase precursor; n=4; Bac... 45 0.003
UniRef50_Q9ZUX0 Cluster: Expressed protein; n=11; cellular organ... 45 0.003
UniRef50_A3H9H5 Cluster: Aldo/keto reductase; n=2; Archaea|Rep: ... 45 0.003
UniRef50_Q8YAN3 Cluster: Lmo0084 protein; n=11; Listeria monocyt... 44 0.004
UniRef50_Q3I1P2 Cluster: Aldo-keto oxidoreductase; n=6; Bacteria... 44 0.004
UniRef50_A6SJ74 Cluster: Putative uncharacterized protein; n=1; ... 44 0.004
UniRef50_Q8PVL5 Cluster: Oxidoreductase, ALDO/KETO reductase fam... 44 0.004
UniRef50_Q4SFJ7 Cluster: Chromosome 7 SCAF14601, whole genome sh... 44 0.005
UniRef50_Q8UIN0 Cluster: Oxidoreductase; n=3; Alphaproteobacteri... 44 0.005
UniRef50_Q6GIV4 Cluster: Aldo/keto reductase family protein; n=1... 44 0.005
UniRef50_Q84M96 Cluster: At1g60680; n=19; cellular organisms|Rep... 44 0.005
UniRef50_A1DD54 Cluster: Aldo/keto reductase; n=3; Trichocomacea... 44 0.005
UniRef50_A1CCJ1 Cluster: Aldo/keto reductase; n=2; Trichocomacea... 44 0.005
UniRef50_Q8TTK4 Cluster: Aldo/keto reductase; n=28; cellular org... 44 0.005
UniRef50_Q0SJ60 Cluster: Possible aldo/keto reductase; n=50; Bac... 44 0.007
UniRef50_A7CVG9 Cluster: Aldo/keto reductase; n=1; Opitutaceae b... 44 0.007
UniRef50_A1RJL6 Cluster: Aldo/keto reductase; n=37; Bacteria|Rep... 44 0.007
UniRef50_Q338B1 Cluster: Auxin-induced protein PCNT115, putative... 44 0.007
UniRef50_Q75DD3 Cluster: ABR094Wp; n=1; Eremothecium gossypii|Re... 44 0.007
UniRef50_A3LSR5 Cluster: D-threo-aldose 1-dehydrogenase; n=5; Sa... 44 0.007
UniRef50_Q8ZXA1 Cluster: Aldo-keto reductase family protein; n=3... 44 0.007
UniRef50_Q3AD20 Cluster: Oxidoreductase, aldo/keto reductase fam... 43 0.009
UniRef50_Q022Y6 Cluster: Aldo/keto reductase precursor; n=2; Sol... 43 0.009
UniRef50_A6WAE5 Cluster: Aldo/keto reductase; n=1; Kineococcus r... 43 0.009
UniRef50_A0GAJ5 Cluster: Aldo/keto reductase precursor; n=9; Pro... 43 0.009
UniRef50_P49261 Cluster: Rho beta-crystallin; n=1; Lepidodactylu... 43 0.009
UniRef50_Q8A1P5 Cluster: Putative oxidoreductase; n=3; Bacteroid... 43 0.012
UniRef50_Q0AL14 Cluster: Aldo/keto reductase; n=1; Maricaulis ma... 43 0.012
UniRef50_Q097V7 Cluster: MocA; n=1; Stigmatella aurantiaca DW4/3... 43 0.012
UniRef50_A6VXU3 Cluster: Aldo/keto reductase; n=14; Proteobacter... 43 0.012
UniRef50_A5FAZ9 Cluster: Aldo/keto reductase; n=1; Flavobacteriu... 43 0.012
UniRef50_A4QYA4 Cluster: Putative uncharacterized protein; n=1; ... 43 0.012
UniRef50_Q1YPT8 Cluster: Aldo/keto reductase; n=1; gamma proteob... 42 0.016
UniRef50_Q01U06 Cluster: Aldo/keto reductase; n=1; Solibacter us... 42 0.016
UniRef50_A1SGJ5 Cluster: Aldo/keto reductase precursor; n=1; Noc... 42 0.016
UniRef50_A0UVR1 Cluster: Aldo/keto reductase; n=3; Bacteria|Rep:... 42 0.016
UniRef50_A7TT39 Cluster: Putative uncharacterized protein; n=1; ... 42 0.016
UniRef50_Q8F4Y9 Cluster: Aldo/keto reductase family protein; n=4... 42 0.021
UniRef50_Q8A955 Cluster: Aldo/keto reductase; n=8; Bacteroidales... 42 0.021
UniRef50_Q09D95 Cluster: Ydhf chain A; n=1; Stigmatella aurantia... 42 0.021
>UniRef50_Q9Y020 Cluster: 3-dehydroecdysone 3beta-reductase
precursor; n=1; Spodoptera littoralis|Rep:
3-dehydroecdysone 3beta-reductase precursor - Spodoptera
littoralis (Egyptian cotton leafworm)
Length = 345
Score = 204 bits (497), Expect = 3e-51
Identities = 99/230 (43%), Positives = 144/230 (62%), Gaps = 1/230 (0%)
Frame = +2
Query: 68 AGFLFCLSALCFTSADLIVPTLQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIY 247
A F+ L+ SA + VP L++ + +P +ALGT+LG G V V+
Sbjct: 4 ASFILLLACCGAMSATIDVPMLKMLNDREMPAIALGTYLGFDKGGAVTSKDKQLRNVVMQ 63
Query: 248 ALEAGYTHIDTAYKYGIEDQVGRALTKKFSEG-LKRESIFITTKLWNSYHEREQVIPALR 424
A++ GY H DTA Y E +VG A+ K EG +KRE +F+TTKLWN++H+REQV A++
Sbjct: 64 AIDLGYRHFDTAAIYNTEAEVGEAIRMKIDEGVIKREDVFLTTKLWNTHHKREQVAVAMK 123
Query: 425 KSLENLNLEYVDLYLIHWPIAMFENDTLLDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQ 604
++L L+YVDL+L+HWPIA+ E D N D+L+TWR + KLG TKSIG+SNFN+
Sbjct: 124 ETLNKTGLDYVDLFLMHWPIALNE-DYSHSNTDYLETWRATEEMVKLGYTKSIGLSNFNK 182
Query: 605 EQIQRIIDSGLEXPSALQIELNLNLQQPELFKFCRENDIVVMAYTPFGSL 754
Q+ ++ P ALQIE++ + Q +L + ++ I+VM Y+PFGSL
Sbjct: 183 LQVATVLQECTIKPVALQIEVHPQIIQEDLITYAKDEGIIVMGYSPFGSL 232
>UniRef50_UPI00015B56A2 Cluster: PREDICTED: similar to GA10458-PA;
n=2; Nasonia vitripennis|Rep: PREDICTED: similar to
GA10458-PA - Nasonia vitripennis
Length = 569
Score = 192 bits (469), Expect = 8e-48
Identities = 93/220 (42%), Positives = 143/220 (65%), Gaps = 11/220 (5%)
Frame = +2
Query: 122 VPTLQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIE 301
VPT+ + G +P++ LGT+L +P G+V + AV YA+E GY H+DTA+ Y E
Sbjct: 3 VPTVTFNDGYKMPMIGLGTFLS-KP-GEVAE-------AVKYAIEVGYRHVDTAFFYENE 53
Query: 302 DQVGRALTKKFSEG-LKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHW 478
++G A+ +K ++G +KRE IF+TTKLW + H+ ++V+PA +KSLENL +Y+DL+L+HW
Sbjct: 54 KEIGSAIREKINDGTIKREDIFVTTKLWCNSHKEDEVVPACKKSLENLGFDYIDLFLVHW 113
Query: 479 PIAMFENDTL----------LDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIID 628
P A D L + D+L+TW+GM + K+ GL +SIG+SNFN EQI R++
Sbjct: 114 PFAFKSGDALTPRDAAGKIEFSDTDYLETWKGMEECKRQGLARSIGLSNFNSEQIARLLS 173
Query: 629 SGLEXPSALQIELNLNLQQPELFKFCRENDIVVMAYTPFG 748
S P Q+E+ +NL Q L +FC++++I V ++P G
Sbjct: 174 SAKIKPVNNQVEVTMNLNQKPLIEFCKKHEITVTGFSPLG 213
Score = 165 bits (400), Expect = 2e-39
Identities = 76/170 (44%), Positives = 112/170 (65%), Gaps = 8/170 (4%)
Frame = +2
Query: 263 YTHIDTAYKYGIEDQVGRALTKKFSEG-LKRESIFITTKLWNSYHEREQVIPALRKSLEN 439
Y HIDTAY Y E +G A+ +K +G +KRE +F+TTKL H+ +V+PA ++SL +
Sbjct: 301 YRHIDTAYLYDNEKYIGNAIREKIKDGTVKREDLFVTTKLSYYAHKESEVVPACKQSLND 360
Query: 440 LNLEYVDLYLIHWPIAMF-------ENDTLLDNVDFLDTWRGMIDAKKLGLTKSIGISNF 598
L L+Y+DLYLIHWPI + LL + D+L+TW+GM + K+ GL +SIG+SNF
Sbjct: 361 LGLDYIDLYLIHWPIRRYFRHNKNASGKLLLSDTDYLETWKGMEECKRQGLARSIGVSNF 420
Query: 599 NQEQIQRIIDSGLEXPSALQIELNLNLQQPELFKFCRENDIVVMAYTPFG 748
N EQI R++++ P Q+E++L L Q L +FC+++DI V Y+P G
Sbjct: 421 NSEQITRLLEAAKIKPVNNQVEVSLKLNQKALIEFCKKHDITVTGYSPLG 470
>UniRef50_UPI00015B56A3 Cluster: PREDICTED: similar to aldo-keto
reductase; n=1; Nasonia vitripennis|Rep: PREDICTED:
similar to aldo-keto reductase - Nasonia vitripennis
Length = 321
Score = 190 bits (462), Expect = 5e-47
Identities = 94/221 (42%), Positives = 139/221 (62%), Gaps = 11/221 (4%)
Frame = +2
Query: 122 VPTLQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIE 301
V + LS G +PV+ LGTW G +V E AV A++AGY H D A YG E
Sbjct: 5 VDEITLSDGNKVPVLGLGTWQGGNDPDEV-------ENAVKLAIDAGYRHFDCASFYGNE 57
Query: 302 DQVGRALTKKFSEGL-KRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHW 478
++G+A+ +K +G+ KRE +F+ TK+WN ++E V+ A ++SL+ L L Y+DLYL+HW
Sbjct: 58 AEIGKAIQEKIDQGVVKREDLFVVTKVWNDERKQELVVAACKRSLKKLGLGYIDLYLVHW 117
Query: 479 PIA---MFE-------NDTLLDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIID 628
P + +++ N LD VD+++TWRGM + KLGLT+SIG+SNFN +Q+ R+++
Sbjct: 118 PFSYPILYQYIVLPTYNAVTLDEVDYIETWRGMEECIKLGLTRSIGVSNFNSQQLTRLLE 177
Query: 629 SGLEXPSALQIELNLNLQQPELFKFCRENDIVVMAYTPFGS 751
S P QIEL++NL Q +L +FC I V Y+PFG+
Sbjct: 178 SASIKPVMNQIELHINLNQKKLREFCASKSIAVTGYSPFGA 218
>UniRef50_Q8WRT0 Cluster: 3-dehydrecdysone 3b-reductase; n=1;
Trichoplusia ni|Rep: 3-dehydrecdysone 3b-reductase -
Trichoplusia ni (Cabbage looper)
Length = 308
Score = 188 bits (459), Expect = 1e-46
Identities = 103/210 (49%), Positives = 133/210 (63%), Gaps = 2/210 (0%)
Frame = +2
Query: 125 PTLQLSSGGNIPVVALGTW-LGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIE 301
P QL+ G IP +ALGT+ G PK QAV++A++AGY HIDTA YG E
Sbjct: 25 PLKQLNDGNAIPSLALGTFGFGDIPK---------VRQAVLWAIQAGYRHIDTAALYGNE 75
Query: 302 DQVGRALTKKFSEGL-KRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHW 478
++VG+ + +GL KRE +F+TTKLWN H R QV+PALR+SL L L YVDLYLIH
Sbjct: 76 EEVGKGIADAIQQGLVKREELFVTTKLWNDKHGRHQVVPALRESLTKLGLSYVDLYLIHS 135
Query: 479 PIAMFENDTLLDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGLEXPSALQ 658
P A EN +D +D L+TW GM +AKKLGL KSIG+SNF+ + R+I P+ Q
Sbjct: 136 PEATNENGDPVD-IDVLNTWNGMEEAKKLGLAKSIGVSNFDTALLDRLIAGSNTVPAVNQ 194
Query: 659 IELNLNLQQPELFKFCRENDIVVMAYTPFG 748
IE++ + Q +L E I VMAY+PFG
Sbjct: 195 IEVHPSKTQEKLVADSHERGIEVMAYSPFG 224
>UniRef50_Q54B70 Cluster: Aldehyde reductase; n=2; Dictyostelium
discoideum|Rep: Aldehyde reductase - Dictyostelium
discoideum AX4
Length = 297
Score = 171 bits (417), Expect = 2e-41
Identities = 95/219 (43%), Positives = 133/219 (60%), Gaps = 10/219 (4%)
Frame = +2
Query: 125 PTLQLSSGGNIPVVALGTWLGHRPK-GKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIE 301
P+ +LSSG IP+V GTW GK V+V AL+AGY HID A Y E
Sbjct: 3 PSFKLSSGHKIPLVGFGTWKAETTLVGKAVEV----------ALDAGYRHIDCAAVYLNE 52
Query: 302 DQVGRALTKKFSEG--LKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIH 475
+VG A TKKF+ +KRE +FIT+KLWN++H++E V PAL ++L +L L+Y+DLYL+H
Sbjct: 53 KEVGEAFTKKFTTEATVKREDVFITSKLWNTFHKKEHVRPALERTLSDLGLQYLDLYLVH 112
Query: 476 WPIAM--FEND-----TLLDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSG 634
WP+A ND + + V +TW M GL KSIG+SNFN + + ++
Sbjct: 113 WPVAFEYTSNDIQTSGSTQEFVSIRETWEEMEKLVDAGLVKSIGLSNFNVQGLMEVLSYA 172
Query: 635 LEXPSALQIELNLNLQQPELFKFCRENDIVVMAYTPFGS 751
P+A Q+EL+ L QPEL KFC +++I + AY+P G+
Sbjct: 173 RIKPAANQVELHPFLSQPELKKFCDKHNIHLTAYSPLGN 211
>UniRef50_Q7PCV3 Cluster: ENSANGP00000031808; n=9;
Endopterygota|Rep: ENSANGP00000031808 - Anopheles
gambiae str. PEST
Length = 316
Score = 171 bits (415), Expect = 3e-41
Identities = 88/223 (39%), Positives = 129/223 (57%), Gaps = 12/223 (5%)
Frame = +2
Query: 119 IVPTLQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGI 298
+VP +G +IP+ LGTW + P G+V Q D A++ GY HID A+ Y
Sbjct: 5 VVPNAIFKNGNSIPMFGLGTW--NSPPGQVAQAVKD-------AIDVGYRHIDCAHVYQN 55
Query: 299 EDQVGRALTKKFSEGL-KRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIH 475
E +VG + K +EG+ KRE +F+T+KLWN++H + V A + +L+NL L+Y+DLYLIH
Sbjct: 56 EHEVGEGIAAKIAEGVVKREDLFVTSKLWNTFHRPDLVEGACKTTLQNLKLDYLDLYLIH 115
Query: 476 WPIAMFENDTLL-----------DNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRI 622
WP+ E L + D++DTW M GL ++IG+SNFN +Q+QR+
Sbjct: 116 WPVGYQEGTELFPMGPDGKTFLFSDADYVDTWPEMEKLVDAGLVRNIGVSNFNAKQVQRV 175
Query: 623 IDSGLEXPSALQIELNLNLQQPELFKFCRENDIVVMAYTPFGS 751
+D P+ QIE + L Q ++ FC E I+V AY+P GS
Sbjct: 176 LDVARIPPATNQIECHPYLHQSKITTFCAEKGIIVTAYSPLGS 218
>UniRef50_Q8VC28 Cluster: Aldo-keto reductase family 1 member C13;
n=11; Theria|Rep: Aldo-keto reductase family 1 member
C13 - Mus musculus (Mouse)
Length = 323
Score = 171 bits (415), Expect = 3e-41
Identities = 94/220 (42%), Positives = 134/220 (60%), Gaps = 13/220 (5%)
Frame = +2
Query: 131 LQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQV 310
++L+ G IP + GT+ K K V + E A + AL+ GY H+DTAY Y +E+++
Sbjct: 8 VKLNDGHLIPALGFGTY-----KPKEVPKSKSLEAACL-ALDVGYRHVDTAYAYQVEEEI 61
Query: 311 GRALTKKFSEGL-KRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPIA 487
G+A+ K G+ KRE +FITTKLW + E V PAL KSL+ L L+YVDLY++H+P+
Sbjct: 62 GQAIQSKIKAGVVKREDLFITTKLWCTCFRPELVKPALEKSLKKLQLDYVDLYIMHYPVP 121
Query: 488 MFEND----------TLLDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDS-G 634
M D +LLD VDF DTW + + K GL KSIG+SNFN Q++RI++ G
Sbjct: 122 MKSGDNDFPVNEQGKSLLDTVDFCDTWERLEECKDAGLVKSIGVSNFNHRQLERILNKPG 181
Query: 635 LE-XPSALQIELNLNLQQPELFKFCRENDIVVMAYTPFGS 751
L+ P Q+E +L L Q +L +C DIV++AY G+
Sbjct: 182 LKYKPVCNQVECHLYLNQRKLLDYCESKDIVLVAYGALGT 221
>UniRef50_A3U9Y0 Cluster: Aldehyde reductase; n=5;
Bacteroidetes|Rep: Aldehyde reductase - Croceibacter
atlanticus HTCC2559
Length = 316
Score = 170 bits (414), Expect = 4e-41
Identities = 91/219 (41%), Positives = 132/219 (60%), Gaps = 11/219 (5%)
Frame = +2
Query: 128 TLQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQ 307
TL+ G +IP + LGTW D ++AV ALE GY HID A Y ED
Sbjct: 3 TLKFRDGDSIPSIGLGTWKSD---------PEDVKKAVKIALENGYKHIDCAAAYDNEDA 53
Query: 308 VGRALTKKFSEG-LKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPI 484
VG A + F G +KRE IF+T+KLWN+ H++E VIPAL+K+L++LNL+Y+DLYL+HWP+
Sbjct: 54 VGEAFKESFESGNVKREDIFVTSKLWNNAHKKEDVIPALKKTLKDLNLDYLDLYLMHWPV 113
Query: 485 AM---------FENDTL-LDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSG 634
A + D L L+ +T MI+AKK GL K +G+SNF++E+++ +
Sbjct: 114 AFKPSVNGFPEKDEDYLSLEEAPLHETLNAMIEAKKQGLIKHVGVSNFSKEKLESLKGKV 173
Query: 635 LEXPSALQIELNLNLQQPELFKFCRENDIVVMAYTPFGS 751
E P Q+EL+ L Q +L+ +C + I++ Y+P GS
Sbjct: 174 EEMPEMNQVELHPYLPQNDLYSYCSKEGILLTGYSPLGS 212
>UniRef50_Q2LZ66 Cluster: GA19341-PA; n=2; Endopterygota|Rep:
GA19341-PA - Drosophila pseudoobscura (Fruit fly)
Length = 315
Score = 167 bits (407), Expect = 3e-40
Identities = 95/221 (42%), Positives = 130/221 (58%), Gaps = 12/221 (5%)
Frame = +2
Query: 125 PTLQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIED 304
P+ LSSG N+P+V LGTW R +VV QAV A++ GY H D A+ YG E
Sbjct: 4 PSFLLSSGRNMPMVGLGTW---RSPPEVVA------QAVKDAIDIGYRHFDCAHIYGNEL 54
Query: 305 QVGRALTKKFSEGL-KRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWP 481
VG A+ +K EGL R+ +FIT+KLWN++H+ E V A SL NL ++Y+DLYL+HWP
Sbjct: 55 HVGVAIREKIQEGLVTRDELFITSKLWNTFHKPELVRAACETSLRNLGIDYLDLYLMHWP 114
Query: 482 IAMFENDTL-----------LDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIID 628
+A D L +++D+LDTW+ M D GL +IG+SNFN++QI R++
Sbjct: 115 MAYKSGDNLYPTCPDTGKAVFEDIDYLDTWKAMEDLVDSGLVNAIGVSNFNEKQINRLLC 174
Query: 629 SGLEXPSALQIELNLNLQQPELFKFCRENDIVVMAYTPFGS 751
P LQIE + L+Q L C +N I V AY+ GS
Sbjct: 175 LAKLKPVMLQIECHPYLRQKSLITLCYDNAIGVTAYSSLGS 215
>UniRef50_UPI0000588153 Cluster: PREDICTED: hypothetical protein;
n=1; Strongylocentrotus purpuratus|Rep: PREDICTED:
hypothetical protein - Strongylocentrotus purpuratus
Length = 333
Score = 166 bits (403), Expect = 8e-40
Identities = 91/221 (41%), Positives = 128/221 (57%), Gaps = 14/221 (6%)
Frame = +2
Query: 128 TLQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQ 307
++ L SG +P+V LGTW K K +V A+ A++AGY H D A YG E +
Sbjct: 4 SVTLPSGHAMPLVGLGTW-----KLKADEVAG----AIGAAVDAGYRHFDCALIYGNEKE 54
Query: 308 VGRALTKKFSE-GLKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPI 484
VG AL + GLKRE +FITTK+WN++H +E V +SL +L L+Y+DLY++HWP+
Sbjct: 55 VGVALREAMQRLGLKREDVFITTKVWNTFHAKEDVAECFNRSLTDLQLDYIDLYIMHWPL 114
Query: 485 AMFEN-------------DTLLDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRII 625
F+N D + +V +L+TW M D K G KS+G+SNFN +Q+ ++
Sbjct: 115 G-FQNLGPTVMFPRTETGDIVYSDVHYLETWSAMEDLVKTGKCKSLGLSNFNSKQLDDVL 173
Query: 626 DSGLEXPSALQIELNLNLQQPELFKFCRENDIVVMAYTPFG 748
PS LQ+E + L Q EL FCRE +VV AY+P G
Sbjct: 174 QHSTVPPSVLQVESHPFLPQVELLNFCRERSVVVSAYSPLG 214
>UniRef50_Q17DN0 Cluster: Aldo-keto reductase; n=5; Culicidae|Rep:
Aldo-keto reductase - Aedes aegypti (Yellowfever
mosquito)
Length = 324
Score = 164 bits (399), Expect = 2e-39
Identities = 95/224 (42%), Positives = 135/224 (60%), Gaps = 15/224 (6%)
Frame = +2
Query: 122 VPTLQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIE 301
+PT++L++G +P + LGT + KG ++ +AV+ A++ G+ HIDTAY Y E
Sbjct: 6 IPTVKLNNGLEMPAIGLGTSMS---KG------DECCKAVMTAIDEGFRHIDTAYNYRNE 56
Query: 302 DQVGRALTKKFSEGL-KRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHW 478
D VGRA+ K EG+ RE +F+TTKLWN++H + V A KSLE+L L+YVDL+LIH
Sbjct: 57 DVVGRAIRAKIEEGVVTREELFVTTKLWNTFHHPDHVPMAFGKSLEHLGLDYVDLFLIHM 116
Query: 479 PIAMF------ENDTLLD---NV-----DFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQ 616
P E T LD NV D++DTW+ M + G SIG+SNFN EQ++
Sbjct: 117 PFGYEFNGWDPEKRTPLDDNGNVLCSDDDYVDTWKAMEKLLESGRVHSIGVSNFNSEQLE 176
Query: 617 RIIDSGLEXPSALQIELNLNLQQPELFKFCRENDIVVMAYTPFG 748
RI+ + P Q+E + + Q L +FC E DIVV A++PFG
Sbjct: 177 RILANCRVKPVTNQVECSARINQKLLIEFCMERDIVVTAHSPFG 220
>UniRef50_Q7JVH6 Cluster: LD24696p; n=2; Sophophora|Rep: LD24696p -
Drosophila melanogaster (Fruit fly)
Length = 311
Score = 161 bits (392), Expect = 2e-38
Identities = 90/227 (39%), Positives = 134/227 (59%), Gaps = 8/227 (3%)
Frame = +2
Query: 119 IVPTLQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGI 298
+ PT++L++G +P + LGTW +D + +AL+ GY H+DTA+ Y
Sbjct: 4 LAPTIRLNNGREMPTLGLGTWKSFE---------SDAYHSTRHALDVGYRHLDTAFVYEN 54
Query: 299 EDQVGRALTKKFSEGL-KRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIH 475
E +VG+A+++K +EG+ RE +F+TTKL +H+ V A R SL NL LEYVDLYL+H
Sbjct: 55 EAEVGQAISEKIAEGVVTREEVFVTTKLGGIHHDPALVERACRLSLSNLGLEYVDLYLMH 114
Query: 476 WPIAM-FEND-----TL-LDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSG 634
P+ F ND TL L +VD+LDTWR M LGLT+SIG+SNFN Q +R++ +
Sbjct: 115 MPVGQKFHNDSNVHGTLELTDVDYLDTWREMEKLVDLGLTRSIGLSNFNAAQTERVLANC 174
Query: 635 LEXPSALQIELNLNLQQPELFKFCRENDIVVMAYTPFGSLFPSKAQP 775
P Q+E + QQ +L + + + +V+ AY P P++ P
Sbjct: 175 RIRPVVNQVECHPGFQQRQLREHAKRHGLVICAYCPLARPQPARQWP 221
>UniRef50_Q9VTL0 Cluster: CG6083-PA; n=4; Diptera|Rep: CG6083-PA -
Drosophila melanogaster (Fruit fly)
Length = 322
Score = 161 bits (391), Expect = 2e-38
Identities = 91/232 (39%), Positives = 133/232 (57%), Gaps = 13/232 (5%)
Frame = +2
Query: 125 PTLQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIED 304
P LS+G N+P++ LGTW R +VV QAV A++ GY H D A+ YG E
Sbjct: 4 PNFLLSNGKNMPMLGLGTW---RSPPEVVT------QAVKDAIDIGYRHFDCAHIYGNEA 54
Query: 305 QVGRALTKKFSEGL-KRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWP 481
QVG AL +K EG+ R+ +FIT+KLWN++H+ + V PA S+ NL ++Y++LYL+HWP
Sbjct: 55 QVGAALREKMDEGVVTRDELFITSKLWNTHHKPDLVRPACETSIRNLGVKYLNLYLMHWP 114
Query: 482 IAMFE------------NDTLLDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRII 625
+A N +++D++DTWR M + GL ++IG+SNFN++Q+ R++
Sbjct: 115 MAYKSGSDNLYPTCPDTNKAAFEDIDYVDTWRAMENLVDEGLCQAIGVSNFNEQQMNRLL 174
Query: 626 DSGLEXPSALQIELNLNLQQPELFKFCRENDIVVMAYTPFGSLFPSKAQPDA 781
P LQIE + L Q L C +N I V AY+ GS +P A
Sbjct: 175 SVAKLKPVVLQIECHPYLSQKPLITLCYDNAIAVTAYSCLGSGHTPYEKPGA 226
>UniRef50_A5E082 Cluster: GCY protein; n=4; Saccharomycetales|Rep:
GCY protein - Lodderomyces elongisporus (Yeast)
(Saccharomyces elongisporus)
Length = 295
Score = 161 bits (391), Expect = 2e-38
Identities = 90/211 (42%), Positives = 129/211 (61%), Gaps = 4/211 (1%)
Frame = +2
Query: 128 TLQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQ 307
T L++G IP + LGTWL +A + AL+ GY HIDTA YG EDQ
Sbjct: 11 TYTLNNGLKIPAIGLGTWLADEEDAAY--------KATLTALKNGYKHIDTAAAYGNEDQ 62
Query: 308 VGRALTKKFSEGLKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPIA 487
VGRA+ G+ R+ IF+TTKLWN H+ + AL +SL+ L LEYVDLYLIHWP++
Sbjct: 63 VGRAIA---DSGVSRDEIFVTTKLWNDQHKDPE--GALDESLKKLGLEYVDLYLIHWPLS 117
Query: 488 MF-ENDTLLDNVDFLDTWRGMIDAKKLG-LTKSIGISNFNQEQIQRIIDS-GLE-XPSAL 655
+ + + D+ DF+DTWR + K G K+IG+SNFN++++ ++++S G+ P
Sbjct: 118 VDPKTEKPYDDYDFVDTWRNLQKIYKEGKKVKAIGVSNFNKKKLDKLLNSEGVNVVPVIN 177
Query: 656 QIELNLNLQQPELFKFCRENDIVVMAYTPFG 748
QIE + L QP+LF + + DI + AY+P G
Sbjct: 178 QIEAHPLLTQPDLFDYLKSKDIYITAYSPLG 208
>UniRef50_UPI00015B4B22 Cluster: PREDICTED: similar to GA15457-PA;
n=1; Nasonia vitripennis|Rep: PREDICTED: similar to
GA15457-PA - Nasonia vitripennis
Length = 388
Score = 160 bits (388), Expect = 5e-38
Identities = 94/221 (42%), Positives = 131/221 (59%), Gaps = 11/221 (4%)
Frame = +2
Query: 122 VPTLQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIE 301
V L+LSSG IP V LGT +++ ++ + A+ ALE GY HIDTA+ Y E
Sbjct: 23 VEKLKLSSGHEIPAVGLGT--------STIKL-DEMDNAISSALENGYRHIDTAFSYDNE 73
Query: 302 DQVGRALTKKFSEGLKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWP 481
+G+ L K F +G KRE IFIT+KL + + + V L++SL++L L+YVD+YLIH P
Sbjct: 74 AAIGKILKKWFDKGGKREDIFITSKLPSQGNRPQSVETYLKRSLKDLGLDYVDMYLIHTP 133
Query: 482 IAMFENDT-----------LLDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIID 628
A+ E + L D+VD W+ M K G KSIG+SNFNQ Q+ I +
Sbjct: 134 FAVKEGENLSSKQDKDGNDLFDDVDHKALWKAMERQVKEGRAKSIGLSNFNQSQVLNIYN 193
Query: 629 SGLEXPSALQIELNLNLQQPELFKFCRENDIVVMAYTPFGS 751
+ PS LQ+E + LQQ +L KFC+E++IV+ AY P GS
Sbjct: 194 NAEIKPSNLQVETHAYLQQKQLRKFCKEHNIVMTAYAPLGS 234
>UniRef50_Q968S3 Cluster: Aldoketoreductase-like protein; n=1;
Orconectes limosus|Rep: Aldoketoreductase-like protein -
Orconectes limosus (Spinycheek crayfish)
Length = 336
Score = 159 bits (386), Expect = 9e-38
Identities = 95/223 (42%), Positives = 128/223 (57%), Gaps = 11/223 (4%)
Frame = +2
Query: 122 VPTLQLSSGGNIPVVALGTW-LGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGI 298
+PT+ L+SG +IPV+ LGT LG K VT E A LE GY H D+A YG
Sbjct: 11 IPTILLNSGSHIPVMGLGTGSLGRNGKMSEEAVTAVLETA----LECGYRHFDSAAYYGN 66
Query: 299 EDQVGRALTKKFSEG-LKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIH 475
E +G+ L + SEG +KRE +FITTKL + + V L+KSL+NL L YVDLYL+H
Sbjct: 67 EAIIGQVLRRWISEGKVKREELFITTKLPTRGNREKDVARFLQKSLDNLRLPYVDLYLVH 126
Query: 476 WPIAMFEND---------TLLDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIID 628
+P + + D T+ D WR M G TK+IG+SNFN +Q+QRII
Sbjct: 127 YPCGILDTDRERLSADEVTVDPTTDIHAIWRAMEAQLAAGKTKNIGLSNFNADQVQRIIK 186
Query: 629 SGLEXPSALQIELNLNLQQPELFKFCRENDIVVMAYTPFGSLF 757
P+ LQ+E+++ +QQ L FC ++DIVV A+ P G F
Sbjct: 187 GCQVRPAVLQVEVHVYMQQGALRAFCAQHDIVVCAFCPLGGPF 229
>UniRef50_Q8K023 Cluster: Aldo-keto reductase family 1 member C18;
n=72; Tetrapoda|Rep: Aldo-keto reductase family 1 member
C18 - Mus musculus (Mouse)
Length = 323
Score = 159 bits (386), Expect = 9e-38
Identities = 85/223 (38%), Positives = 133/223 (59%), Gaps = 13/223 (5%)
Frame = +2
Query: 122 VPTLQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIE 301
+ ++L+ G +IPV+ GT+ + + ++ A++ G+ HID ++ Y E
Sbjct: 5 IQKIELNDGHSIPVLGFGTYATEE------HLKKKSMESTKIAIDVGFCHIDCSHLYQNE 58
Query: 302 DQVGRALTKKFSEG-LKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHW 478
+++G+A+ K +G +KRE IF T+KLW++ H E V P+L SL LNL+YVDLYLIH+
Sbjct: 59 EEIGQAILSKIEDGTVKREDIFYTSKLWSTSHRPELVRPSLENSLRKLNLDYVDLYLIHF 118
Query: 479 PIAMFENDTLL----------DNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIID 628
P+++ + LL D VD DTW M K GL KSIG+SNFN+ Q++ I++
Sbjct: 119 PVSLKPGNELLPKDEHGNLIFDTVDLCDTWEAMEKCKDAGLAKSIGVSNFNRRQLEMILN 178
Query: 629 S-GLE-XPSALQIELNLNLQQPELFKFCRENDIVVMAYTPFGS 751
GL+ P Q+E +L L Q +L +C+ NDIV++AY G+
Sbjct: 179 KPGLKYKPVCNQVECHLYLNQSKLLAYCKMNDIVLVAYGALGT 221
>UniRef50_Q41399 Cluster: Chalcone reductase; n=4;
eudicotyledons|Rep: Chalcone reductase - Sesbania
rostrata
Length = 322
Score = 158 bits (383), Expect = 2e-37
Identities = 79/224 (35%), Positives = 132/224 (58%), Gaps = 10/224 (4%)
Frame = +2
Query: 110 ADLIVPTLQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYK 289
A+ +P + L+SG +PV+ +GT + RP V+ + A++ GY H D+A
Sbjct: 2 AEKKIPEVLLNSGHKMPVIGMGTSVESRPSNDVLA------SIFVDAIQVGYRHFDSASV 55
Query: 290 YGIEDQVGRALTKKFSEGL--KRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDL 463
YG E+ +G A++K +GL R+ +FIT+K WN+ + ++PAL+ +L+ L +EYVDL
Sbjct: 56 YGTEEAIGMAVSKAIEQGLIKSRDEVFITSKPWNTDAHHDLIVPALKTTLKKLGMEYVDL 115
Query: 464 YLIHWPIAM---FENDTLLDNVDFLD-----TWRGMIDAKKLGLTKSIGISNFNQEQIQR 619
YLIHWP+ + EN + D L TW+ M + +LGL KSIGI N+ +++ +
Sbjct: 116 YLIHWPVRLRHDLENPVIFSKEDLLPFDIEGTWKAMEECYRLGLAKSIGICNYGTKKLTK 175
Query: 620 IIDSGLEXPSALQIELNLNLQQPELFKFCRENDIVVMAYTPFGS 751
+++ P+ Q+E+N + QQ L +FC++ I V A++P G+
Sbjct: 176 LLEIATIPPAVNQVEMNPSWQQGNLREFCKQKGIHVSAWSPLGA 219
>UniRef50_Q2UGR1 Cluster: Aldo/keto reductase family proteins; n=2;
Ascomycota|Rep: Aldo/keto reductase family proteins -
Aspergillus oryzae
Length = 323
Score = 158 bits (383), Expect = 2e-37
Identities = 94/223 (42%), Positives = 134/223 (60%), Gaps = 15/223 (6%)
Frame = +2
Query: 128 TLQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQ 307
T +L+SG NIP + LGTWL +P ++ E AV AL AGY HID A Y E++
Sbjct: 6 TFKLNSGYNIPAIGLGTWLS-KP--------HEVENAVEAALRAGYRHIDAAACYQNENE 56
Query: 308 VGRALTKKFSEGLKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPIA 487
VG K G+ R+ IFIT+KLWN++H E V A+ K+L++L +Y+DLYLIHWP+A
Sbjct: 57 VGNGWKKS---GVPRDQIFITSKLWNTHHHPEHVEEAVNKTLKDLQTDYLDLYLIHWPVA 113
Query: 488 M-FENDTL-----------LDNVDFLDTWRG---MIDAKKLGLTKSIGISNFNQEQIQRI 622
N+TL L NV DTW +++AKK+ +SIGISNF Q++I +
Sbjct: 114 FEHTNETLTPIDPVTKRFRLANVPIADTWAALEKLVEAKKI---RSIGISNFTQDKIDDL 170
Query: 623 IDSGLEXPSALQIELNLNLQQPELFKFCRENDIVVMAYTPFGS 751
+ + P+ QIE + LQQP L K+ +E +I+ +AY+P G+
Sbjct: 171 LKTAKIPPAVNQIEAHPYLQQPGLHKYLKEKNILSVAYSPLGN 213
>UniRef50_Q6TY50 Cluster: Reductase 2; n=10; Magnoliophyta|Rep:
Reductase 2 - Hydrangea macrophylla (Bigleaf hydrangea)
Length = 321
Score = 157 bits (382), Expect = 3e-37
Identities = 87/221 (39%), Positives = 134/221 (60%), Gaps = 10/221 (4%)
Frame = +2
Query: 122 VPTLQLSSGGN-IPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGI 298
+P + LSSGG +PV+ LGT + V+ +AV AL+ GY H DTA Y
Sbjct: 5 IPEVPLSSGGRKMPVLGLGTAADPPVDPETVR------KAVTEALKLGYRHFDTAALYNS 58
Query: 299 EDQVGRALTKKFSEGL--KRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLI 472
E +G A+ + EGL R+ +FIT+KLW S RE V PAL+K+L+NL LEY+D+YLI
Sbjct: 59 EQPLGDAIAEALGEGLIKSRDELFITSKLWCSDAHRENVEPALQKTLKNLKLEYIDMYLI 118
Query: 473 HWPIAM----FENDTLLDN---VDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDS 631
HWP++ +E ++ +D+ W M + +KLGLTK+IG+SNF+ +++ ++ +
Sbjct: 119 HWPVSSKPGNYEYPIKKEDFLQMDYKSVWEAMEECQKLGLTKAIGVSNFSCKKLSDVLAN 178
Query: 632 GLEXPSALQIELNLNLQQPELFKFCRENDIVVMAYTPFGSL 754
P+ Q+E+N QQ +L +FC+ N I+V+AY G++
Sbjct: 179 AKVPPAVNQVEVNPCWQQKQLTEFCKSNGILVVAYAALGAV 219
>UniRef50_Q0VGY1 Cluster: 3-alpha-hydroxysteroid dehydrogenase;
n=13; Tetrapoda|Rep: 3-alpha-hydroxysteroid
dehydrogenase - Xenopus tropicalis (Western clawed frog)
(Silurana tropicalis)
Length = 324
Score = 156 bits (379), Expect = 6e-37
Identities = 85/221 (38%), Positives = 132/221 (59%), Gaps = 14/221 (6%)
Frame = +2
Query: 131 LQLSSGGNIPVVALGTWLGHR-PKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQ 307
++L+ G +PV+ GT+ + PK E+ A++ GY HID A+ YG E++
Sbjct: 9 VELNDGHKMPVIGFGTYAPPKFPKSLA-------EEGTKVAIDVGYRHIDCAFLYGNEEE 61
Query: 308 VGRALTKKFSEG-LKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPI 484
VGRA+ K ++G +KRE +F T KLW++ H E+V PAL KSL++L L+Y+DL++IH P+
Sbjct: 62 VGRAIRAKIADGTVKREDVFYTGKLWSTSHTPERVRPALEKSLKDLQLDYMDLFIIHMPM 121
Query: 485 AMFENDTLL----------DNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIID-S 631
D L N D DTW+ + K GL +SIG+SNFN +Q++ I++
Sbjct: 122 EFKPGDDLFPADENGKFIYHNTDLRDTWKALEKCKDAGLVRSIGVSNFNHKQLELILNMP 181
Query: 632 GLE-XPSALQIELNLNLQQPELFKFCRENDIVVMAYTPFGS 751
GL+ P Q+E ++ L Q +L +FC+ DIV++ Y+ GS
Sbjct: 182 GLKYKPVCNQVECHVYLNQSKLLEFCKSKDIVLVGYSVLGS 222
>UniRef50_Q9NAI5 Cluster: Putative uncharacterized protein; n=3;
Caenorhabditis|Rep: Putative uncharacterized protein -
Caenorhabditis elegans
Length = 316
Score = 156 bits (379), Expect = 6e-37
Identities = 89/222 (40%), Positives = 130/222 (58%), Gaps = 11/222 (4%)
Frame = +2
Query: 119 IVPTLQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGI 298
+V +L+L+SG +IP + LGTW +P G+V A+ A+ AGY HID A+ Y
Sbjct: 1 MVQSLKLNSGYSIPAIGLGTWQS-KP-GEVAA-------AIKTAVAAGYRHIDCAHVYQN 51
Query: 299 EDQVGRALTKKFSEG-LKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIH 475
+ +VG AL + EG +KRE +FIT+K+WN++H + + L +L L YVDL LIH
Sbjct: 52 QKEVGEALKEILDEGKVKREELFITSKVWNTFHSEAKAHENIDIILSDLQLSYVDLMLIH 111
Query: 476 WPIAMFENDTLL----------DNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRII 625
WP E L +VD+L+TW+ A+K G +SIG+SNF QIQR+
Sbjct: 112 WPQGYAEGAELFPAGENGKMRYSDVDYLETWKAFEAAQKAGKCRSIGLSNFTHSQIQRVW 171
Query: 626 DSGLEXPSALQIELNLNLQQPELFKFCRENDIVVMAYTPFGS 751
D+ P+ LQ+EL+ Q +L +FC+E IVV+ Y+P G+
Sbjct: 172 DAAEVKPACLQVELHPYFTQVKLREFCKEKGIVVVGYSPLGN 213
>UniRef50_P14550 Cluster: Alcohol dehydrogenase [NADP+]; n=44;
Bilateria|Rep: Alcohol dehydrogenase [NADP+] - Homo
sapiens (Human)
Length = 325
Score = 156 bits (379), Expect = 6e-37
Identities = 89/228 (39%), Positives = 124/228 (54%), Gaps = 12/228 (5%)
Frame = +2
Query: 137 LSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQVGR 316
L +G +P++ LGTW K + QV + AV YAL GY HID A YG E ++G
Sbjct: 8 LHTGQKMPLIGLGTW-----KSEPGQV----KAAVKYALSVGYRHIDCAAIYGNEPEIGE 58
Query: 317 ALTKKFSEG--LKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPIAM 490
AL + G + RE +F+T+KLWN+ H E V PALRK+L +L LEY+DLYL+HWP A
Sbjct: 59 ALKEDVGPGKAVPREELFVTSKLWNTKHHPEDVEPALRKTLADLQLEYLDLYLMHWPYAF 118
Query: 491 FENDT----------LLDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGLE 640
D D+ + +TW+ + GL +++G+SNFN QI I+
Sbjct: 119 ERGDNPFPKNADGTICYDSTHYKETWKALEALVAKGLVQALGLSNFNSRQIDDILSVASV 178
Query: 641 XPSALQIELNLNLQQPELFKFCRENDIVVMAYTPFGSLFPSKAQPDAP 784
P+ LQ+E + L Q EL C+ + V AY+P GS + PD P
Sbjct: 179 RPAVLQVECHPYLAQNELIAHCQARGLEVTAYSPLGSSDRAWRDPDEP 226
>UniRef50_P45376 Cluster: Aldose reductase; n=21; Bilateria|Rep:
Aldose reductase - Mus musculus (Mouse)
Length = 316
Score = 155 bits (377), Expect = 1e-36
Identities = 91/231 (39%), Positives = 133/231 (57%), Gaps = 13/231 (5%)
Frame = +2
Query: 131 LQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQV 310
L+L++G +P + LGTW P G+V + AV A++ GY HID A Y E +V
Sbjct: 5 LELNNGTKMPTLGLGTWKS--PPGQVTE-------AVKVAIDLGYRHIDCAQVYQNEKEV 55
Query: 311 GRALTKKFSEGL-KRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPIA 487
G AL +K E + KR+ +FI +KLW ++H++ V A +K+L +L L+Y+DLYLIHWP
Sbjct: 56 GVALQEKLKEQVVKRQDLFIVSKLWCTFHDKSMVKGAFQKTLSDLQLDYLDLYLIHWPTG 115
Query: 488 M----------FENDTLLDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDS-G 634
+ + + DF+DTW M GL K+IG+SNFN QI+RI++ G
Sbjct: 116 FKPGPDYFPLDASGNVIPSDTDFVDTWTAMEQLVDEGLVKTIGVSNFNPLQIERILNKPG 175
Query: 635 LE-XPSALQIELNLNLQQPELFKFCRENDIVVMAYTPFGSLFPSKAQPDAP 784
L+ P+ QIE + L Q +L ++C IVV AY+P GS A+P+ P
Sbjct: 176 LKYKPAVNQIECHPYLTQEKLIEYCHSKGIVVTAYSPLGSPDRPWAKPEDP 226
>UniRef50_P26690 Cluster: NAD(P)H-dependent 6'-deoxychalcone
synthase; n=3; Papilionoideae|Rep: NAD(P)H-dependent
6'-deoxychalcone synthase - Glycine max (Soybean)
Length = 315
Score = 155 bits (376), Expect = 1e-36
Identities = 79/182 (43%), Positives = 116/182 (63%), Gaps = 9/182 (4%)
Frame = +2
Query: 224 DTEQAVIYALEAGYTHIDTAYKYGIEDQVGRALTKKFSEGL-KRESIFITTKLWNSYHER 400
DT++A+I A++ GY H DTA YG E +G AL + GL R+ +F+T+KLW + +
Sbjct: 37 DTKEAIIEAVKQGYRHFDTAAAYGSEQALGEALKEAIHLGLVSRQDLFVTSKLWVTENHP 96
Query: 401 EQVIPALRKSLENLNLEYVDLYLIHWPIAM--------FENDTLLDNVDFLDTWRGMIDA 556
V+PALRKSL+ L LEY+DLYLIHWP++ E + LL D W M +
Sbjct: 97 HLVLPALRKSLKTLQLEYLDLYLIHWPLSSQPGKFSFPIEVEDLLP-FDVKGVWESMEEC 155
Query: 557 KKLGLTKSIGISNFNQEQIQRIIDSGLEXPSALQIELNLNLQQPELFKFCRENDIVVMAY 736
+KLGLTK+IG+SNF+ +++Q ++ P Q+E+NL QQ +L +FC+EN I+V A+
Sbjct: 156 QKLGLTKAIGVSNFSVKKLQNLLSVATIRPVVDQVEMNLAWQQKKLREFCKENGIIVTAF 215
Query: 737 TP 742
+P
Sbjct: 216 SP 217
>UniRef50_P15121 Cluster: Aldose reductase; n=72; Eumetazoa|Rep:
Aldose reductase - Homo sapiens (Human)
Length = 316
Score = 155 bits (375), Expect = 2e-36
Identities = 93/231 (40%), Positives = 136/231 (58%), Gaps = 13/231 (5%)
Frame = +2
Query: 131 LQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQV 310
L L++G +P++ LGTW P G+V + AV A++ GY HID A+ Y E++V
Sbjct: 5 LLLNNGAKMPILGLGTWKS--PPGQVTE-------AVKVAIDVGYRHIDCAHVYQNENEV 55
Query: 311 GRALTKKFSEGL-KRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPIA 487
G A+ +K E + KRE +FI +KLW +YHE+ V A +K+L +L L+Y+DLYLIHWP
Sbjct: 56 GVAIQEKLREQVVKREELFIVSKLWCTYHEKGLVKGACQKTLSDLKLDYLDLYLIHWPTG 115
Query: 488 ------MFEND----TLLDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDS-G 634
F D + + + LDTW M + GL K+IGISNFN Q++ I++ G
Sbjct: 116 FKPGKEFFPLDESGNVVPSDTNILDTWAAMEELVDEGLVKAIGISNFNHLQVEMILNKPG 175
Query: 635 LE-XPSALQIELNLNLQQPELFKFCRENDIVVMAYTPFGSLFPSKAQPDAP 784
L+ P+ QIE + L Q +L ++C+ IVV AY+P GS A+P+ P
Sbjct: 176 LKYKPAVNQIECHPYLTQEKLIQYCQSKGIVVTAYSPLGSPDRPWAKPEDP 226
>UniRef50_UPI000065D0BD Cluster: Homolog of Homo sapiens "AKR1B1
protein.; n=1; Takifugu rubripes|Rep: Homolog of Homo
sapiens "AKR1B1 protein. - Takifugu rubripes
Length = 330
Score = 101 bits (241), Expect(2) = 2e-36
Identities = 54/123 (43%), Positives = 78/123 (63%), Gaps = 1/123 (0%)
Frame = +2
Query: 119 IVPTLQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGI 298
++P++ L++G +PV+ LGTW GK V T +AV A+ AGY HIDTAY Y
Sbjct: 1 MIPSVTLNTGALMPVLGLGTW----KSGKGV-----TTEAVKVAIGAGYRHIDTAYVYEN 51
Query: 299 EDQVGRALTKKFSEGL-KRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIH 475
E +VG + +G+ KRE +FI +KLW ++H V A K+L +LNL+YVDLYL+H
Sbjct: 52 ETEVGAGVQAMIDQGVVKREELFIVSKLWCTFHTPSLVRGACEKTLSSLNLDYVDLYLMH 111
Query: 476 WPI 484
+P+
Sbjct: 112 FPM 114
Score = 74.9 bits (176), Expect(2) = 2e-36
Identities = 41/98 (41%), Positives = 56/98 (57%), Gaps = 2/98 (2%)
Frame = +2
Query: 497 NDTLLDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDS-GLE-XPSALQIELN 670
N + D FLDTW M + GL K+IGISNFN++QI+ +++ GL+ P+ QIE +
Sbjct: 153 NQLICDGTSFLDTWEAMEELVDDGLAKAIGISNFNKDQIEAVLNKPGLKHKPATNQIECH 212
Query: 671 LNLQQPELFKFCRENDIVVMAYTPFGSLFPSKAQPDAP 784
+L Q +L FCR I V A+ GS S A D P
Sbjct: 213 PHLNQEKLIHFCRSRGISVTAFACLGSADRSWASADEP 250
>UniRef50_Q8CI22 Cluster: 2310005E10Rik protein; n=30;
Tetrapoda|Rep: 2310005E10Rik protein - Mus musculus
(Mouse)
Length = 316
Score = 154 bits (374), Expect = 2e-36
Identities = 88/229 (38%), Positives = 128/229 (55%), Gaps = 13/229 (5%)
Frame = +2
Query: 137 LSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQVGR 316
L +G +P+V LGTW P KV +AV A++AGY HID AY Y E +VG
Sbjct: 7 LLTGAKMPIVGLGTWKS--PPAKV-------REAVKVAIDAGYRHIDCAYVYQNESEVGE 57
Query: 317 ALTKKFSE-GLKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPIAMF 493
A+ +K E +KRE +FI +KLW+++ E+ V A + +L +L L+Y+DLYLIHWP
Sbjct: 58 AIQEKIQEKAVKREDLFIVSKLWSTFFEKSLVKKAFQNTLSDLKLDYLDLYLIHWPQGFQ 117
Query: 494 ENDTLLDNVD----------FLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDS-GLE 640
+ L D FLD W M + GL K++G+SNFN QI+R+++ GL+
Sbjct: 118 SGNVFLPTDDKGSILSSKYTFLDAWEAMEELVDQGLVKALGVSNFNHFQIERLLNKPGLK 177
Query: 641 -XPSALQIELNLNLQQPELFKFCRENDIVVMAYTPFGSLFPSKAQPDAP 784
P Q+E + L Q +L ++C I + AY+P GS A+P+ P
Sbjct: 178 HKPVTNQVECHPYLTQEKLTQYCHSKGITITAYSPLGSPDRPSAKPEDP 226
>UniRef50_Q2S340 Cluster: Aldehyde reductase; n=10; Bacteria|Rep:
Aldehyde reductase - Salinibacter ruber (strain DSM
13855)
Length = 321
Score = 154 bits (374), Expect = 2e-36
Identities = 86/218 (39%), Positives = 128/218 (58%), Gaps = 10/218 (4%)
Frame = +2
Query: 128 TLQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQ 307
++ +G +P++ LGTW P G+V + AV ALEAGY H+D A Y E +
Sbjct: 3 SISFENGDEMPMIGLGTWKS--PPGEVYE-------AVTTALEAGYRHVDCAPIYKNETE 53
Query: 308 VGRALTKKFSEG-LKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPI 484
VG AL+ F G ++R+ +++T+KLWN+ H + V PAL ++L +L L+ +DLYLIHWP+
Sbjct: 54 VGAALSDSFDAGGIRRDDVWVTSKLWNNAHHPDDVRPALEQTLSDLRLDALDLYLIHWPV 113
Query: 485 AMF-ENDTLLDNVDFL--------DTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGL 637
A+ E D DF+ +TW M KK GL + IG+SNF+ +Q I+D+G
Sbjct: 114 ALQPEVDFPESPDDFVSPEAVPLTETWAAMEALKKDGLVRHIGVSNFSVPNLQMILDAGE 173
Query: 638 EXPSALQIELNLNLQQPELFKFCRENDIVVMAYTPFGS 751
P Q+E++ L QPEL F ++I + AY+P GS
Sbjct: 174 VRPEMNQVEMHPYLPQPELVSFAEAHNIPITAYSPLGS 211
>UniRef50_Q96UH3 Cluster: Aldehyde reductase; n=13;
Pezizomycotina|Rep: Aldehyde reductase - Coccidioides
posadasii
Length = 314
Score = 154 bits (373), Expect = 3e-36
Identities = 84/218 (38%), Positives = 129/218 (59%), Gaps = 10/218 (4%)
Frame = +2
Query: 128 TLQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQ 307
T +L++G +IP + GTW Q N E AV+ AL AGY HIDTA YG E
Sbjct: 7 TFRLNTGEDIPAIGFGTW----------QDENAQEDAVLTALSAGYRHIDTAAVYGTEKA 56
Query: 308 VGRALTKKFSEGLKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPIA 487
+GRAL + L R+ +FIT+KLWN+ H E V A+ +SL+NL ++Y+DLYL+HWP A
Sbjct: 57 IGRALARS---RLSRDELFITSKLWNNKHRPEDVEQAIDQSLKNLEIDYLDLYLMHWPAA 113
Query: 488 MFENDTLLD----------NVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGL 637
D + ++D++DT++ M K G TK+IGISNF++ +++R+++S
Sbjct: 114 FAPGDDMFPKDSQGNSKTVDIDYVDTYKAMEKLVKSGKTKAIGISNFSKGEMERLLESCS 173
Query: 638 EXPSALQIELNLNLQQPELFKFCRENDIVVMAYTPFGS 751
P+ +Q+EL+ LQQ + ++ + I V Y+ G+
Sbjct: 174 IVPAVMQMELHPWLQQNDFVEWLKSKGIHVTQYSSLGN 211
>UniRef50_Q5BKE9 Cluster: LOC594893 protein; n=5; Xenopus
tropicalis|Rep: LOC594893 protein - Xenopus tropicalis
(Western clawed frog) (Silurana tropicalis)
Length = 345
Score = 152 bits (369), Expect = 1e-35
Identities = 94/236 (39%), Positives = 135/236 (57%), Gaps = 28/236 (11%)
Frame = +2
Query: 128 TLQLSSGGNIPVVALGTWL------------GH---RPKGKVVQVTNDTEQAVIYALEAG 262
++QL G +PVVA GT+ GH G +D A AL+ G
Sbjct: 8 SIQLHDGRWMPVVAFGTFYPFTFPGDSQANPGHCAGTKHGTEKSFIDDVRVATKMALDLG 67
Query: 263 YTHIDTAYKYGIEDQVGRALTKKFSEG-LKRESIFITTKLWNSYHEREQVIPALRKSLEN 439
Y H+D A+ Y E VG+A +KF++G LKRE +F T+KLWN++H+ V PAL K+L
Sbjct: 68 YRHVDGAFLYSSETGVGQAFREKFADGTLKREDLFYTSKLWNTFHQPHLVRPALEKTLSF 127
Query: 440 LNLEYVDLYLIHWPIA------MF---ENDT-LLDNVDFLDTWRGMIDAKKLGLTKSIGI 589
L ++YVDLYLIH P++ +F E+ T D D L TW+ + + + GL KSIG+
Sbjct: 128 LQMDYVDLYLIHMPMSFKPAEELFPKNEDGTCAFDQPDLLQTWQALEECRDAGLVKSIGV 187
Query: 590 SNFNQEQIQRIIDS-GLE-XPSALQIELNLNLQQPELFKFCRENDIVVMAYTPFGS 751
SNFN+ Q++ I++ GL+ P QIE + L Q ++ +FC+ DIVV+AY GS
Sbjct: 188 SNFNRRQLEMILNKPGLKYKPVCNQIECHPYLNQKQMLEFCKSKDIVVVAYGVLGS 243
>UniRef50_Q16K66 Cluster: Aldo-keto reductase; n=2; Aedes
aegypti|Rep: Aldo-keto reductase - Aedes aegypti
(Yellowfever mosquito)
Length = 303
Score = 152 bits (368), Expect = 1e-35
Identities = 88/220 (40%), Positives = 129/220 (58%), Gaps = 8/220 (3%)
Frame = +2
Query: 131 LQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQV 310
L L++G +IP + LGT+ K+ +D A+ A+E GY IDTA+ Y E V
Sbjct: 2 LALNNGHSIPPIGLGTY-------KITG--SDGVAAIKSAVEFGYRLIDTAFVYNNEQVV 52
Query: 311 GRALTKKFSEG--LKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPI 484
G+AL + FS+G + RE +FI +KL ++H E V R SLE L L+YVDLYL+H P+
Sbjct: 53 GQALREIFSQGNDINREDVFIVSKLGPTFHRPEAVEKGCRLSLERLGLDYVDLYLMHTPV 112
Query: 485 AMFE----NDT--LLDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGLEXP 646
A + ND + D V L+TW+ + + ++ GL +SIG+SNFN+EQ+ I+ G P
Sbjct: 113 AARDSGDGNDRSEIDDEVTPLETWKALEECQRKGLVRSIGVSNFNEEQLMEIVTHGSIRP 172
Query: 647 SALQIELNLNLQQPELFKFCRENDIVVMAYTPFGSLFPSK 766
Q+E ++ Q +L KFC I++MAY+P G P K
Sbjct: 173 VVNQVECSIGFHQVKLRKFCNREGILIMAYSPLGKPKPGK 212
>UniRef50_Q6CFG7 Cluster: Yarrowia lipolytica chromosome B of strain
CLIB122 of Yarrowia lipolytica; n=9; Ascomycota|Rep:
Yarrowia lipolytica chromosome B of strain CLIB122 of
Yarrowia lipolytica - Yarrowia lipolytica (Candida
lipolytica)
Length = 337
Score = 151 bits (366), Expect = 2e-35
Identities = 88/219 (40%), Positives = 126/219 (57%), Gaps = 13/219 (5%)
Frame = +2
Query: 137 LSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQVGR 316
L++G IP + LGTW K +V E A+ E GY HIDTA+ Y ED VG
Sbjct: 36 LNNGKTIPAIGLGTW-----KSTTEEVAGAVECALT---EGGYRHIDTAFNYRNEDAVGL 87
Query: 317 ALTKKFSEGLKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPIAMFE 496
+ + +G+KRE IF+TTK+W +YH+R V L SLE L L+YVD+ LIHWP+ +
Sbjct: 88 GIKRAMEKGVKREDIFVTTKIWVTYHDR--VEENLDMSLERLGLDYVDMLLIHWPVPLNP 145
Query: 497 N--DTLL----DNVDFLD-------TWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGL 637
N D + D +D TW+ M K G TKSIG+SNF+ ++ ++
Sbjct: 146 NGNDPVYPLRPDGSRDIDESGSQPKTWKQMEAVLKTGKTKSIGVSNFSIPYLEELLKEAE 205
Query: 638 EXPSALQIELNLNLQQPELFKFCRENDIVVMAYTPFGSL 754
P+ Q+EL+ L Q EL +FC++N+IV+ A++PFGS+
Sbjct: 206 VVPAVNQVELHPLLPQLELMEFCKKNNIVMTAFSPFGSV 244
>UniRef50_Q7QK25 Cluster: ENSANGP00000019775; n=2; Anopheles gambiae
str. PEST|Rep: ENSANGP00000019775 - Anopheles gambiae
str. PEST
Length = 319
Score = 151 bits (365), Expect = 3e-35
Identities = 84/225 (37%), Positives = 131/225 (58%), Gaps = 16/225 (7%)
Frame = +2
Query: 122 VPTLQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIE 301
VPT++ S+G IPV+ GT+L KG+ V++ A++ GY HIDTA+ Y E
Sbjct: 5 VPTVRFSNGYEIPVLGYGTYLAQ--KGQCVELVKK-------AIDLGYRHIDTAFLYENE 55
Query: 302 DQVGRALTKKFSEG-LKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHW 478
++G+A+ K +EG ++RE +F+TTKLWN++H+ + V A R+S + L++ Y+DL+L+H
Sbjct: 56 VEIGQAIRDKIAEGVIRREDVFVTTKLWNTFHDPQHVEEAFRRSFDMLDIGYIDLFLMHS 115
Query: 479 PIAM----FE----------NDTLLDNVDFLDTWRGMIDAKKL-GLTKSIGISNFNQEQI 613
P+ + +E + L +VD+++TW+ M G +SIG+SNFN EQI
Sbjct: 116 PMGVQFSGYEYADMQPKDAAGNMLFSDVDYVETWKAMEKLVTAGGRVRSIGLSNFNSEQI 175
Query: 614 QRIIDSGLEXPSALQIELNLNLQQPELFKFCRENDIVVMAYTPFG 748
+RI+ P Q+E N Q +L FC+ I V AY P G
Sbjct: 176 ERILQIATVKPVNNQVEANPGYDQRKLIAFCQARGITVTAYGPMG 220
>UniRef50_A2QBD7 Cluster: Catalytic activity: an alcohol + NADP(+)
<=> an aldehyde + NADPH; n=4; Trichocomaceae|Rep:
Catalytic activity: an alcohol + NADP(+) <=> an aldehyde
+ NADPH - Aspergillus niger
Length = 323
Score = 149 bits (362), Expect = 7e-35
Identities = 84/215 (39%), Positives = 123/215 (57%), Gaps = 10/215 (4%)
Frame = +2
Query: 137 LSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQVGR 316
+++G IP V GTW + K ++V N AV AL GY HID A Y E +VG
Sbjct: 9 INTGAKIPAVGFGTW-----QAKPLEVEN----AVEVALREGYRHIDCAAIYRNETEVGN 59
Query: 317 ALTKKFSEGLKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPIAM-- 490
+ K G+ RE IFIT KLWN+ H E V PAL K+L++L + Y+DLYL+HWP A
Sbjct: 60 GIRKS---GVPREEIFITGKLWNTKHAPEDVEPALDKTLQDLGVAYLDLYLMHWPCAFKG 116
Query: 491 ------FENDTLLD--NVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGLEXP 646
+D + D N+D++ T+R M G ++IG+SNFN +++ ++ P
Sbjct: 117 GDKWFPLNDDGVFDLANIDYITTYRAMEKLLATGKVRAIGVSNFNIRRLEELLGQVSVVP 176
Query: 647 SALQIELNLNLQQPELFKFCRENDIVVMAYTPFGS 751
+ QIE + LQQP+L +FC+ I++ AY+P G+
Sbjct: 177 AVNQIEAHPYLQQPDLLQFCQSKGILIEAYSPLGN 211
>UniRef50_Q23320 Cluster: Putative uncharacterized protein; n=4;
Caenorhabditis|Rep: Putative uncharacterized protein -
Caenorhabditis elegans
Length = 320
Score = 149 bits (361), Expect = 9e-35
Identities = 91/211 (43%), Positives = 123/211 (58%), Gaps = 1/211 (0%)
Frame = +2
Query: 122 VPTLQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIE 301
VP LS+G +P + LGTW +GK V + N A+ AGY HIDTA Y E
Sbjct: 5 VPIFTLSNGVLMPSIGLGTWQMTGEEGKTV-IRN--------AVLAGYRHIDTATLYQNE 55
Query: 302 DQVGRALTKKFSEG-LKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHW 478
Q+G AL + F+EG LKRE IFITTK + + V ALR SL+ L L+YVDLYL H
Sbjct: 56 HQIGDALAELFAEGILKREDIFITTKAFCHEVAPDVVEEALRNSLKRLRLDYVDLYLAHI 115
Query: 479 PIAMFENDTLLDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGLEXPSALQ 658
P + ++ + +V D WRG LGLTK+IG+SNFN+ QI RI++ A Q
Sbjct: 116 PASTKDDGSFRSDVKVEDIWRGFEKVYGLGLTKAIGVSNFNESQIVRIMNIQKVPIHASQ 175
Query: 659 IELNLNLQQPELFKFCRENDIVVMAYTPFGS 751
+EL+L L Q + C++++I++ AY GS
Sbjct: 176 LELHLYLPQKAHRELCKKHNILITAYATLGS 206
>UniRef50_A2EYY6 Cluster: Oxidoreductase, aldo/keto reductase family
protein; n=9; Trichomonas vaginalis G3|Rep:
Oxidoreductase, aldo/keto reductase family protein -
Trichomonas vaginalis G3
Length = 308
Score = 148 bits (359), Expect = 2e-34
Identities = 90/227 (39%), Positives = 132/227 (58%), Gaps = 17/227 (7%)
Frame = +2
Query: 155 IPVVALGTWLGHRPKGKVVQVTNDTEQAVIYAL-EAGYTHIDTAYKYGIEDQVGRALTKK 331
IP + LGTW R + D A+ YA+ EAGY HID A Y ED VG+AL +
Sbjct: 4 IPTIGLGTWKSPR--------SEDLVNAITYAIKEAGYVHIDCALCYENEDIVGQALQQC 55
Query: 332 FSEGLKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPIAMFEN---- 499
+ G+KRE+I+IT+KLWN++H E V A RK+L++L L+Y+DLYL+H+P A F+N
Sbjct: 56 WDSGIKRENIWITSKLWNTHHRLEIVEEACRKTLKDLRLDYLDLYLMHYPFA-FQNTGIG 114
Query: 500 ----------DTLLDN-VDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGLE-X 643
+T+ D+ V +DTW+ M + GL K IG+SN+ Q++R+ S +
Sbjct: 115 GSLNPLDEKGNTIFDDGVSLIDTWKAMEKLVEKGLVKRIGVSNWTINQLERLKYSDAKTT 174
Query: 644 PSALQIELNLNLQQPELFKFCRENDIVVMAYTPFGSLFPSKAQPDAP 784
P Q+E NL +QQ L ++ + I+V Y+ G+ P A+PD P
Sbjct: 175 PYTNQVEFNLYMQQGPLREYMHKEGIIVTGYSTLGT--PDWAKPDEP 219
>UniRef50_Q8SSK6 Cluster: ALDOSE REDUCTASE; n=1; Encephalitozoon
cuniculi|Rep: ALDOSE REDUCTASE - Encephalitozoon
cuniculi
Length = 301
Score = 148 bits (359), Expect = 2e-34
Identities = 92/230 (40%), Positives = 131/230 (56%), Gaps = 11/230 (4%)
Frame = +2
Query: 116 LIVPTLQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYG 295
+I T +L++G IP V LGTW G + + E A+ AL GY HIDTA+ YG
Sbjct: 1 MICKTQKLNNGKEIPTVGLGTW-GMEDEAVL-------EGAIRNALSLGYRHIDTAFIYG 52
Query: 296 IEDQVGRALTKKFSEGL-KRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLI 472
E +G L K F EG+ +R+ +FIT+KLWN++H + LR+SL +L ++YVDLYLI
Sbjct: 53 NEKMIGNILKKLFDEGVVQRKDLFITSKLWNTFHGCPE--DGLRRSLNDLQMDYVDLYLI 110
Query: 473 HWPIAM-------FENDTLLDNV---DFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRI 622
HWP+ E+ NV D + W+ M LGL KSIGISNF + ++I
Sbjct: 111 HWPVTFDPAPDGTVESCGKKYNVGKFDAVGVWKKMEALVDLGLAKSIGISNFGKANTEKI 170
Query: 623 IDSGLEXPSALQIELNLNLQQPELFKFCRENDIVVMAYTPFGSLFPSKAQ 772
+ + P+A+QIEL+ L Q EL +F + I V++Y+ GS S A+
Sbjct: 171 LGTCRICPAAIQIELHPYLNQKELVEFMKSKGIQVISYSSLGSAPGSSAK 220
>UniRef50_Q96JD6 Cluster: Aldo-keto reductase family 1 member C-like
protein 2; n=37; Euteleostomi|Rep: Aldo-keto reductase
family 1 member C-like protein 2 - Homo sapiens (Human)
Length = 320
Score = 94.7 bits (225), Expect(2) = 3e-34
Identities = 52/113 (46%), Positives = 68/113 (60%), Gaps = 1/113 (0%)
Frame = +2
Query: 149 GNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQVGRALTK 328
G+IP V L +W GKV + AV A++AGY H D AY Y E +VG +
Sbjct: 2 GDIPAVGLSSWKAS--PGKVTE-------AVKEAIDAGYRHFDCAYFYHNEREVGAGIRC 52
Query: 329 KFSEG-LKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPI 484
K EG ++RE +FI TKLW + H++ V A RKSL+ L L Y+DLYLIHWP+
Sbjct: 53 KIKEGAVRREDLFIATKLWCTCHKKSLVETACRKSLKALKLNYLDLYLIHWPM 105
Score = 74.5 bits (175), Expect(2) = 3e-34
Identities = 38/86 (44%), Positives = 50/86 (58%), Gaps = 2/86 (2%)
Frame = +2
Query: 497 NDTLLDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDS-GLE-XPSALQIELN 670
N + + DFLDTW M D GL K+IG+SNFN EQ++R+++ GL P QIE +
Sbjct: 139 NMVIPSDTDFLDTWEAMEDLVITGLVKNIGVSNFNHEQLERLLNKPGLRFKPLTNQIECH 198
Query: 671 LNLQQPELFKFCRENDIVVMAYTPFG 748
L Q L FC+ D+ V AY P G
Sbjct: 199 PYLTQKNLISFCQSRDVSVTAYRPLG 224
>UniRef50_Q88SL1 Cluster: Oxidoreductase; n=51; Lactobacillales|Rep:
Oxidoreductase - Lactobacillus plantarum
Length = 286
Score = 147 bits (356), Expect = 4e-34
Identities = 85/218 (38%), Positives = 124/218 (56%), Gaps = 2/218 (0%)
Frame = +2
Query: 104 TSADLIVPTLQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTA 283
T+ + T L++G IP+V GTW P G+V +V+ AL+AGY HIDTA
Sbjct: 2 TALTKLTDTYTLNNGTKIPIVGFGTW--QTPDGQVAY------DSVLAALKAGYRHIDTA 53
Query: 284 YKYGIEDQVGRALTKKFSEGLKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDL 463
YG E+ VG+A+ G+ RE +F+TTKLWN+ H + AL SL L L+YVDL
Sbjct: 54 AAYGNEESVGKAIA---DSGVAREDLFVTTKLWNADHGYDAAKKALDTSLAKLGLDYVDL 110
Query: 464 YLIHW--PIAMFENDTLLDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGL 637
YLIHW P AM +N L+ DTWR M +A ++IG+SNF + + ++ +
Sbjct: 111 YLIHWPNPAAMRDNWEQLN----ADTWRAMEEAYTARKARAIGVSNFRPKHLDALLKTAK 166
Query: 638 EXPSALQIELNLNLQQPELFKFCRENDIVVMAYTPFGS 751
P+ QI LN + + E+ + R++DI+ AY+P G+
Sbjct: 167 VVPAVNQIFLNPSDMEDEVVAYNRKHDILSEAYSPLGT 204
>UniRef50_Q0IBY6 Cluster: Alcohol dehydrogenase; n=2;
Chroococcales|Rep: Alcohol dehydrogenase - Synechococcus
sp. (strain CC9311)
Length = 336
Score = 147 bits (356), Expect = 4e-34
Identities = 80/225 (35%), Positives = 131/225 (58%), Gaps = 13/225 (5%)
Frame = +2
Query: 119 IVPTLQ---LSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYK 289
++PT+Q LS+G +P++ LGT K + QV +A+ + GY HID A
Sbjct: 15 VIPTMQYASLSNGDRMPLLGLGTG-----KSESRQVYKSVREAI----KIGYRHIDCASI 65
Query: 290 YGIEDQVGRALTKKF-SEGLKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLY 466
YG E++VG A+ + + R ++IT+KLW++ H + V AL +SL+NL ++Y++LY
Sbjct: 66 YGNEEEVGDAIRDAIQNHEITRSELWITSKLWSNCHGKNHVEAALSQSLQNLGVDYLNLY 125
Query: 467 LIHWPIAMFENDTLLDNVDFL---------DTWRGMIDAKKLGLTKSIGISNFNQEQIQR 619
LIHWP+ + T ++VD L +TW M + GLTK IG+SNF +++Q+
Sbjct: 126 LIHWPVGIRPEKTFAESVDDLLTPEESPISETWEAMESTRDKGLTKHIGVSNFTVKKLQQ 185
Query: 620 IIDSGLEXPSALQIELNLNLQQPELFKFCRENDIVVMAYTPFGSL 754
++ + P Q+E + LQQP L ++C +I++ AY+P GS+
Sbjct: 186 LVSHCKQKPEVNQVEHHPLLQQPTLIEYCASEEILITAYSPLGSM 230
>UniRef50_A2R6Z3 Cluster: Catalytic activity: an alcohol + NADP(+)
<=> an aldehyde + NADPH; n=9; Pezizomycotina|Rep:
Catalytic activity: an alcohol + NADP(+) <=> an aldehyde
+ NADPH - Aspergillus niger
Length = 345
Score = 147 bits (356), Expect = 4e-34
Identities = 85/220 (38%), Positives = 125/220 (56%), Gaps = 12/220 (5%)
Frame = +2
Query: 128 TLQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQ 307
T +L++G ++P V LGTW + ++ AVI AL+ GY HID A YG E +
Sbjct: 6 TFKLNTGYDMPAVGLGTWQSKK---------DEVRDAVIAALKCGYRHIDAAAVYGNEQE 56
Query: 308 VGRALTKKFSEGLKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPIA 487
VG + G+ RE IF+T+KLWN++H E V A+ KSL +L +Y+DLYLIHWP+A
Sbjct: 57 VGDGMRLS---GVPREEIFLTSKLWNTHHHPENVEEAVDKSLADLQTDYLDLYLIHWPVA 113
Query: 488 ----------MFENDTLLDNVD--FLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDS 631
+ E L+D VD DTW M + G +SIG+SNF +E+I+ ++ +
Sbjct: 114 FRYSTTTIQPVNEQTGLIDVVDVPIKDTWAAMEKLVEKGKVRSIGVSNFTREKIEELLKT 173
Query: 632 GLEXPSALQIELNLNLQQPELFKFCRENDIVVMAYTPFGS 751
P+ QIE + LQQ +L ++ + IVV Y+P G+
Sbjct: 174 AKITPAVNQIEAHPFLQQRDLLEWSTQKGIVVAGYSPLGN 213
>UniRef50_A7CUW0 Cluster: 2,5-didehydrogluconate reductase; n=6;
Bacteria|Rep: 2,5-didehydrogluconate reductase -
Opitutaceae bacterium TAV2
Length = 334
Score = 146 bits (354), Expect = 7e-34
Identities = 89/220 (40%), Positives = 123/220 (55%), Gaps = 1/220 (0%)
Frame = +2
Query: 92 ALCFTSADLIVPTLQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYA-LEAGYT 268
A C+T ++PTL LS G +IP + LG W Q+ +D I A AGY
Sbjct: 51 AWCYTMR--MIPTLPLSDGTSIPQLGLGVW----------QMPDDGAGVPIQAAFNAGYR 98
Query: 269 HIDTAYKYGIEDQVGRALTKKFSEGLKRESIFITTKLWNSYHEREQVIPALRKSLENLNL 448
IDTA YG E+ VGRA+ + GL R+ ++ITTK+WNS + + A+R+SL L L
Sbjct: 99 AIDTAPIYGNEEGVGRAIR---ASGLPRKELYITTKVWNSAQGYDSTLRAVRESLGRLQL 155
Query: 449 EYVDLYLIHWPIAMFENDTLLDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIID 628
EYVDLYLIHWP+ + ++DTW+ + K GL +SIG+SNF +QR+ D
Sbjct: 156 EYVDLYLIHWPVPKIDR--------YVDTWKALAKIKADGLARSIGVSNFTPVYLQRLFD 207
Query: 629 SGLEXPSALQIELNLNLQQPELFKFCRENDIVVMAYTPFG 748
P Q+EL+ LQQ EL F ++ IV A++P G
Sbjct: 208 ETGIVPVVNQVELHPRLQQHELRAFHAKHRIVTEAWSPLG 247
>UniRef50_P14065 Cluster: Protein GCY; n=13; Saccharomycetales|Rep:
Protein GCY - Saccharomyces cerevisiae (Baker's yeast)
Length = 312
Score = 146 bits (354), Expect = 7e-34
Identities = 91/227 (40%), Positives = 127/227 (55%), Gaps = 20/227 (8%)
Frame = +2
Query: 131 LQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQV 310
L L++G IP + LGTW ND +AV+ AL+ GY HIDTA Y EDQV
Sbjct: 12 LSLNTGAQIPQIGLGTWQSKE---------NDAYKAVLTALKDGYRHIDTAAIYRNEDQV 62
Query: 311 GRALTKKFSEGLKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPI-- 484
G+A+ G+ RE IF+TTKLW + H +V AL +SL+ L L+YVDLYL+HWP
Sbjct: 63 GQAIK---DSGVPREEIFVTTKLWCTQHHEPEV--ALDQSLKRLGLDYVDLYLMHWPARL 117
Query: 485 --AMFENDTLLD--------------NVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQ 616
A +N+ +L N +F+ TW M + K G TK++G+SNF+ ++
Sbjct: 118 DPAYIKNEDILSVPTKKDGSRAVDITNWNFIKTWELMQELPKTGKTKAVGVSNFSINNLK 177
Query: 617 RIIDS--GLEXPSALQIELNLNLQQPELFKFCRENDIVVMAYTPFGS 751
++ S P+A Q+E++ L Q EL FC+ IVV AY+P GS
Sbjct: 178 DLLASQGNKLTPAANQVEIHPLLPQDELINFCKSKGIVVEAYSPLGS 224
>UniRef50_P51857 Cluster: 3-oxo-5-beta-steroid 4-dehydrogenase (EC
1.3.1.3) (Delta(4)-3- ketosteroid 5-beta-reductase);
n=124; cellular organisms|Rep: 3-oxo-5-beta-steroid
4-dehydrogenase (EC 1.3.1.3) (Delta(4)-3- ketosteroid
5-beta-reductase) - Homo sapiens (Human)
Length = 326
Score = 146 bits (354), Expect = 7e-34
Identities = 86/220 (39%), Positives = 128/220 (58%), Gaps = 13/220 (5%)
Frame = +2
Query: 131 LQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQV 310
+ LS G +IP++ LGT+ + K T+ V A++ GY HID AY Y E +V
Sbjct: 10 IPLSDGNSIPIIGLGTYSEPKSTPKGACATS-----VKVAIDTGYRHIDGAYIYQNEHEV 64
Query: 311 GRALTKKFSEG-LKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPIA 487
G A+ +K +EG ++RE IF KLW + H E V P L ++L L L+YVDLY+I P+A
Sbjct: 65 GEAIREKIAEGKVRREDIFYCGKLWATNHVPEMVRPTLERTLRVLQLDYVDLYIIEVPMA 124
Query: 488 MFENDTLL---DNVDFL-------DTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDS-G 634
D + +N +L TW M K GL KS+G+SNFN+ Q++ I++ G
Sbjct: 125 FKPGDEIYPRDENGKWLYHKSNLCATWEAMEACKDAGLVKSLGVSNFNRRQLELILNKPG 184
Query: 635 LE-XPSALQIELNLNLQQPELFKFCRENDIVVMAYTPFGS 751
L+ P + Q+E + QP+L KFC+++DIV+ AY+P G+
Sbjct: 185 LKHKPVSNQVECHPYFTQPKLLKFCQQHDIVITAYSPLGT 224
>UniRef50_UPI00015B40FA Cluster: PREDICTED: similar to CG2767-PA;
n=2; Nasonia vitripennis|Rep: PREDICTED: similar to
CG2767-PA - Nasonia vitripennis
Length = 356
Score = 145 bits (351), Expect = 2e-33
Identities = 90/221 (40%), Positives = 122/221 (55%), Gaps = 13/221 (5%)
Frame = +2
Query: 128 TLQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQ 307
T++LSSG ++P++ LGTW P + E AV ALE+GY HIDTA+ YG E+
Sbjct: 27 TIKLSSGHDMPMIGLGTW--QMPPEAI-------EVAVTAALESGYRHIDTAFTYGNEEA 77
Query: 308 VGRALTKKFSEGLKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPIA 487
+G+ L K F +G KRE +FITTKL E V L+ SLE L LEYV++YLIH P A
Sbjct: 78 IGKTLKKWFDKGGKREDLFITTKLPPIGMRAEYVESYLKLSLEKLGLEYVNMYLIHKPFA 137
Query: 488 MF------------ENDTLLD-NVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIID 628
+ +LD + D + WR M K G +SIG+SNFN+ Q+ + +
Sbjct: 138 FVKDKYKYEPALNPDGSVVLDTDTDHVAIWRAMEKQVKAGRVRSIGLSNFNKSQLLNVYE 197
Query: 629 SGLEXPSALQIELNLNLQQPELFKFCRENDIVVMAYTPFGS 751
PS LQIEL QQ + + C E +I V A++ GS
Sbjct: 198 HAEIKPSNLQIELQAYNQQRPMRELCAERNITVTAFSTLGS 238
>UniRef50_A7SIT3 Cluster: Predicted protein; n=1; Nematostella
vectensis|Rep: Predicted protein - Nematostella
vectensis
Length = 323
Score = 144 bits (349), Expect = 3e-33
Identities = 80/217 (36%), Positives = 130/217 (59%), Gaps = 11/217 (5%)
Frame = +2
Query: 134 QLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQVG 313
+L++G +IP +ALGTW + +V N AV A+E GY HID A YG E ++G
Sbjct: 9 KLNTGASIPAMALGTWQSSKE-----EVGN----AVRLAIELGYRHIDCAEIYGNEGEIG 59
Query: 314 RALTKKFSEG-LKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPIAM 490
AL++ +EG +KRE +F+T+KLW H + V+PA + +L+NL L+Y+DLYLIH P+A
Sbjct: 60 EALSEVLTEGKVKREELFVTSKLWCDSHHPDDVLPACQATLKNLQLDYLDLYLIHIPVAF 119
Query: 491 FENDTLLDNV----------DFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGLE 640
+ L ++ +TW+ M GL K+IG+SNF+ +++ +++++
Sbjct: 120 KKGVRLPHSIAEGIIGYTPEGVQNTWQAMEGLVAKGLCKAIGVSNFSVKRLNKLLETASI 179
Query: 641 XPSALQIELNLNLQQPELFKFCRENDIVVMAYTPFGS 751
P+ Q+EL+ L Q +L +FC I++ AY+P G+
Sbjct: 180 VPACNQVELHPYLPQEKLKEFCDSKGILLTAYSPLGN 216
>UniRef50_Q5FK98 Cluster: Oxidoreductase; n=8; Lactobacillales|Rep:
Oxidoreductase - Lactobacillus acidophilus
Length = 285
Score = 143 bits (346), Expect = 6e-33
Identities = 80/208 (38%), Positives = 122/208 (58%)
Frame = +2
Query: 128 TLQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQ 307
T L++G IP++ GTW P G+V E++V+ AL GY HIDTA YG ED
Sbjct: 9 TYTLNNGVKIPIIGFGTW--QTPDGEVA------EESVLAALNCGYRHIDTASAYGNEDS 60
Query: 308 VGRALTKKFSEGLKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPIA 487
VGRA+ K G+ R +FITTKLWNS H E+ A+ +SL +L L+Y+D+YLIHWP
Sbjct: 61 VGRAIQKS---GINRHELFITTKLWNSDHGYEKTKKAIDQSLLDLKLDYLDMYLIHWPNP 117
Query: 488 MFENDTLLDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGLEXPSALQIEL 667
D + ++ ++WR M +A + G ++IG+SNF + + ++++ P QI L
Sbjct: 118 SSMRDHWAE-IN-AESWRAMEEAVRAGKIRAIGVSNFRKHHLDALMETAEIKPVVNQIFL 175
Query: 668 NLNLQQPELFKFCRENDIVVMAYTPFGS 751
N + Q E+ ++ D++ AY+P G+
Sbjct: 176 NPSDLQSEVVTENKKLDLLSEAYSPLGT 203
>UniRef50_P27800 Cluster: Aldehyde reductase 1; n=18; root|Rep:
Aldehyde reductase 1 - Sporobolomyces salmonicolor
Length = 323
Score = 143 bits (346), Expect = 6e-33
Identities = 85/226 (37%), Positives = 125/226 (55%), Gaps = 15/226 (6%)
Frame = +2
Query: 119 IVPTLQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGI 298
+V T L++G ++ +V GTW + Q V A+E GY H+D A Y
Sbjct: 1 MVGTTTLNTGASLELVGYGTWQA---------APGEVGQGVKVAIETGYRHLDLAKVYSN 51
Query: 299 EDQVGRALTKKFSEGLKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHW 478
+ +VG A+ + G+KRE +FIT+KLWN+ H EQV PAL +L+ L LEY+DLYLIHW
Sbjct: 52 QPEVGAAIKEA---GVKREDLFITSKLWNNSHRPEQVEPALDDTLKELGLEYLDLYLIHW 108
Query: 479 PIA----------MF----ENDTLLD-NVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQI 613
P+A +F + + LD V +DTW+ M+ G K+IG+SNF+ + +
Sbjct: 109 PVAFPPEGDITQNLFPKANDKEVKLDLEVSLVDTWKAMVKLLDTGKVKAIGVSNFDAKMV 168
Query: 614 QRIIDSGLEXPSALQIELNLNLQQPELFKFCRENDIVVMAYTPFGS 751
II++ PS QIE + L QPEL + +I + AY+P G+
Sbjct: 169 DAIIEATGVTPSVNQIERHPLLLQPELIAHHKAKNIHITAYSPLGN 214
>UniRef50_Q7ZWA4 Cluster: Zgc:56622; n=6; cellular organisms|Rep:
Zgc:56622 - Danio rerio (Zebrafish) (Brachydanio rerio)
Length = 289
Score = 142 bits (344), Expect = 1e-32
Identities = 72/185 (38%), Positives = 110/185 (59%), Gaps = 11/185 (5%)
Frame = +2
Query: 230 EQAVIYALEAGYTHIDTAYKYGIEDQVGRALTKKFSEGL-KRESIFITTKLWNSYHEREQ 406
++A A+ AGY HIDTA+ Y E VG A+ K +G+ +R+ +FI +KLW ++H E
Sbjct: 3 QRACEAAIAAGYRHIDTAFCYRNEVDVGMAIQNKIQQGIIRRQDMFIVSKLWGTHHAPED 62
Query: 407 VIPALRKSLENLNLEYVDLYLIHWPIAMF--------END--TLLDNVDFLDTWRGMIDA 556
+ KSL +L L+Y+D YL+H+P+ + E D L ++D++D WRGM
Sbjct: 63 IPVCFNKSLSDLQLDYLDQYLVHFPVGLKKVGDELFPERDGKILTTDIDYVDVWRGMEAL 122
Query: 557 KKLGLTKSIGISNFNQEQIQRIIDSGLEXPSALQIELNLNLQQPELFKFCRENDIVVMAY 736
K G KSIG+SNF EQI R++ P+ Q+EL+ L Q +L +C+ +I + A+
Sbjct: 123 KATGKVKSIGVSNFTMEQIDRLLSVAKIPPAVNQVELHPYLVQSDLIDYCKSKNIALTAH 182
Query: 737 TPFGS 751
+PFGS
Sbjct: 183 SPFGS 187
>UniRef50_Q83N50 Cluster: 2,5-diketo-D-gluconic acid reductase; n=2;
Tropheryma whipplei|Rep: 2,5-diketo-D-gluconic acid
reductase - Tropheryma whipplei (strain Twist)
(Whipple's bacillus)
Length = 283
Score = 142 bits (343), Expect = 1e-32
Identities = 85/208 (40%), Positives = 118/208 (56%)
Frame = +2
Query: 122 VPTLQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIE 301
VP++ L G +IP LGT+ P N+ V A+E GY HIDTA Y E
Sbjct: 9 VPSVLLGDGVSIPQFGLGTY--ELPP-------NEASSVVQSAIELGYRHIDTASLYANE 59
Query: 302 DQVGRALTKKFSEGLKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWP 481
+VGRA+ S G+KRE F+TTKLWNS + + A +SL+ L+L+YVDLYLIHWP
Sbjct: 60 REVGRAIA---SSGIKREEFFVTTKLWNSDQPKPR--EAFERSLDLLSLDYVDLYLIHWP 114
Query: 482 IAMFENDTLLDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGLEXPSALQI 661
E +++ W +++ K+ G KS+G+SNF E I +I ++G PS QI
Sbjct: 115 CPPSEL--------YINVWEVLLELKESGRAKSVGVSNFLSEHIDKIKEAGFPLPSVNQI 166
Query: 662 ELNLNLQQPELFKFCRENDIVVMAYTPF 745
EL+ LQQ EL CR + I + ++ PF
Sbjct: 167 ELHPWLQQRELVLSCRNDGIQIESWGPF 194
>UniRef50_Q17G72 Cluster: Aldo-keto reductase; n=9;
Endopterygota|Rep: Aldo-keto reductase - Aedes aegypti
(Yellowfever mosquito)
Length = 316
Score = 142 bits (343), Expect = 1e-32
Identities = 86/218 (39%), Positives = 118/218 (54%), Gaps = 11/218 (5%)
Frame = +2
Query: 131 LQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQV 310
+ +G +P + GTW + E+A+ ALEAGY HIDTA Y E +
Sbjct: 7 ITFENGTTMPALGFGTWRAS---------DEEVEKALNEALEAGYRHIDTAPVYLNEKTI 57
Query: 311 GRALTKKFSEG-LKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPIA 487
G+ L + G + R+ +FI TKL V L+ SL++L LEYVDLY +H P
Sbjct: 58 GKVLKEWMDAGKVTRDELFIVTKLPPHGTRASTVEKFLKNSLDDLQLEYVDLYHVHVPFT 117
Query: 488 MFEND----------TLLDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGL 637
+ E D L D + W+ M + + GL ++IG+SNFNQ QIQRI+D+
Sbjct: 118 VPEVDGPFLVEDGLIVLETTTDHVALWKAMEEVYEAGLARNIGLSNFNQRQIQRILDNCQ 177
Query: 638 EXPSALQIELNLNLQQPELFKFCRENDIVVMAYTPFGS 751
P+ LQIE ++ LQQPEL KFC+ N I V AY+P GS
Sbjct: 178 IKPANLQIENHIYLQQPELVKFCKANGITVTAYSPLGS 215
>UniRef50_Q5KI95 Cluster: Aldo-keto reductase, putative; n=14;
Dikarya|Rep: Aldo-keto reductase, putative -
Cryptococcus neoformans (Filobasidiella neoformans)
Length = 353
Score = 142 bits (343), Expect = 1e-32
Identities = 93/241 (38%), Positives = 131/241 (54%), Gaps = 15/241 (6%)
Frame = +2
Query: 101 FTSADLIVPT-LQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHID 277
F S + PT +L++G +IP + LGTW + K +V QAV +AL+AGY HID
Sbjct: 28 FNSLIMSAPTSFKLNTGASIPAIGLGTW-----QAKAGEV----RQAVAHALKAGYRHID 78
Query: 278 TAYKYGIEDQVGRALTKKFSEGLKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYV 457
A Y ED+VG + G+ R IF+T+K+W+SYH+R V L +L++L +Y+
Sbjct: 79 GALCYQNEDEVGLGIK---DSGVPRSEIFLTSKVWSSYHDR--VEECLDTTLKSLQTDYL 133
Query: 458 DLYLIHWPIAMFENDT------------LLD-NVDFLDTWRGMIDAKKLGLTKSIGISNF 598
DLYLIHWP+ + N T LD + D TW M D K G K+IG+SN
Sbjct: 134 DLYLIHWPVRLAPNGTHPLFPVKPDGSRNLDWDWDQAKTWAQMEDVLKKGKAKAIGLSNA 193
Query: 599 NQEQIQRIIDSGLEXPSALQIELNLNLQQPELFKFCRENDIVVMAYTPFGSL-FPSKAQP 775
I+ II +G P+ Q+EL+ Q L K+C+E I++ AY+P GS P P
Sbjct: 194 GIPIIEHIIKTGKVTPAVNQVELHPYCPQHALLKYCKEKGILLEAYSPLGSTSSPLHEDP 253
Query: 776 D 778
D
Sbjct: 254 D 254
>UniRef50_UPI0000519CC2 Cluster: PREDICTED: similar to CG2767-PA;
n=1; Apis mellifera|Rep: PREDICTED: similar to CG2767-PA
- Apis mellifera
Length = 321
Score = 141 bits (342), Expect = 2e-32
Identities = 92/221 (41%), Positives = 122/221 (55%), Gaps = 13/221 (5%)
Frame = +2
Query: 128 TLQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQ 307
T+ L +G +P++ GTW + E A+ ALEAGY HIDTA Y E
Sbjct: 5 TILLPNGELMPIIGFGTWQAQE---------KELEDALNIALEAGYRHIDTATSYENEKV 55
Query: 308 VGRALTKKF-SEGLKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPI 484
+G L F S+ LKR IFI TKL + E V ++ SL+NL LEY+DLYLIH PI
Sbjct: 56 IGDVLKNWFDSKKLKRSDIFIVTKLPAVGNRAEDVEKWIKTSLQNLRLEYLDLYLIHVPI 115
Query: 485 AMFE-NDTL----------LDN-VDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIID 628
+ D L LDN + ++ W M K G TK+IG+SNFN QI+RI+
Sbjct: 116 GFEKVGDILHPFDENGHIRLDNSTNHVEIWAEMEKQVKCGRTKAIGLSNFNISQIKRILK 175
Query: 629 SGLEXPSALQIELNLNLQQPELFKFCRENDIVVMAYTPFGS 751
+ S LQIEL++ QQ EL KFC++ +I + AY+P GS
Sbjct: 176 NTKMKISMLQIELHVYFQQKELVKFCKQENIPITAYSPLGS 216
>UniRef50_UPI0000498F1F Cluster: oxidoreductase, aldo/keto reductase
family; n=2; Entamoeba histolytica HM-1:IMSS|Rep:
oxidoreductase, aldo/keto reductase family - Entamoeba
histolytica HM-1:IMSS
Length = 305
Score = 141 bits (342), Expect = 2e-32
Identities = 74/208 (35%), Positives = 122/208 (58%), Gaps = 3/208 (1%)
Frame = +2
Query: 137 LSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQVGR 316
L++G IP + LGTW+ + +AV A++ GY HID A YG E +VG
Sbjct: 7 LNNGYKIPKLGLGTWMS---------ANGEVGKAVEIAIKNGYRHIDCAKAYGNEKEVGD 57
Query: 317 ALTKKFSEG-LKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPIAMF 493
+ ++G +KRE +F+TTKLW++ +E V PA +SL+ L LEY+DLY+IH P+
Sbjct: 58 GIKSAIAKGYVKREELFVTTKLWSTDKHKEDVRPACLESLKKLQLEYLDLYIIHIPLTAD 117
Query: 494 EN--DTLLDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGLEXPSALQIEL 667
+ + + + +TWR M + GL KSIG+SNFN ++++ ++ P+ Q E
Sbjct: 118 KKTGEFTEEIIPIEETWREMEKLVEEGLVKSIGVSNFNIKKLEELLAIAKIQPAVNQFEF 177
Query: 668 NLNLQQPELFKFCRENDIVVMAYTPFGS 751
++ Q+P+L +FC++++I + Y P G+
Sbjct: 178 HIYYQRPKLHQFCKKHNIHITGYCPLGN 205
>UniRef50_Q01J82 Cluster: OSIGBa0152K17.5 protein; n=28;
Magnoliophyta|Rep: OSIGBa0152K17.5 protein - Oryza
sativa (Rice)
Length = 323
Score = 141 bits (342), Expect = 2e-32
Identities = 82/218 (37%), Positives = 118/218 (54%), Gaps = 9/218 (4%)
Frame = +2
Query: 122 VPTLQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIE 301
VP + L G P+ A+G +G T A + ALE G+ H DTA YG E
Sbjct: 4 VPEVALRHGAGRPMPAVG--VGTADSAATSPETK--RGAALAALEVGFRHFDTAALYGTE 59
Query: 302 DQVGRALTKKFSEGL--KRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIH 475
+G A+ + GL RE +F+TTKLW + V+P+LR+SL NL +EYVDLYL+H
Sbjct: 60 APLGEAIAEATRRGLVASREEVFVTTKLWCTQCHPGLVLPSLRESLRNLQMEYVDLYLVH 119
Query: 476 WPIAMFENDTLL-----DNV--DFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSG 634
WPI++ +L D V DF WR M + +LGL K+IG+SNF + + +++
Sbjct: 120 WPISVKPGPPMLPVKREDAVPFDFEGVWRAMEECHRLGLAKAIGVSNFTTKHLDKLLAVA 179
Query: 635 LEXPSALQIELNLNLQQPELFKFCRENDIVVMAYTPFG 748
P+ Q+E+N QQ + ++C I V AY+P G
Sbjct: 180 TIPPAVNQVEMNPVWQQRTVREYCAAKGIRVAAYSPLG 217
>UniRef50_A5KSS3 Cluster: Aldehyde reductase; n=1; candidate
division TM7 genomosp. GTL1|Rep: Aldehyde reductase -
candidate division TM7 genomosp. GTL1
Length = 299
Score = 141 bits (341), Expect = 2e-32
Identities = 82/218 (37%), Positives = 120/218 (55%), Gaps = 11/218 (5%)
Frame = +2
Query: 131 LQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQV 310
L L + +P++ GTW P G T V A++AGY HID A YG E +V
Sbjct: 4 LTLRNKQTLPLLGYGTW--ELPTGT-------TADLVETAIKAGYRHIDCAMIYGNEKEV 54
Query: 311 GRALTKKFSEGL-KRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPIA 487
G + + +G+ KRE +F+T+KLWN+ H + V A RK+L +L L+Y+DLYLIHW +A
Sbjct: 55 GEGIRRTIDQGVVKREDLFVTSKLWNTDHAQVDVGVACRKTLNDLGLDYLDLYLIHWGVA 114
Query: 488 MFENDTL--LDN--------VDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGL 637
D L LD+ + +TW+ M + + GL KS+G++NF + ++
Sbjct: 115 FEHGDNLEPLDDDGVAKFSFISMKETWQAMEELVEQGLVKSMGVANFTAPMLLDLLSYAK 174
Query: 638 EXPSALQIELNLNLQQPELFKFCRENDIVVMAYTPFGS 751
P+ QIEL+ L Q +L FC +I V AY+PFGS
Sbjct: 175 IKPAVHQIELHPYLAQNDLVAFCYSQNIAVTAYSPFGS 212
>UniRef50_UPI000023D0F1 Cluster: hypothetical protein FG03517.1;
n=1; Gibberella zeae PH-1|Rep: hypothetical protein
FG03517.1 - Gibberella zeae PH-1
Length = 364
Score = 140 bits (339), Expect = 4e-32
Identities = 80/205 (39%), Positives = 118/205 (57%), Gaps = 1/205 (0%)
Frame = +2
Query: 152 NIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQVGRALTKK 331
+IP LGTWL KG VV AV YAL+ GY HIDTA + ED+VG+ +
Sbjct: 59 DIPAFGLGTWLAG--KGVVVP-------AVEYALKGGYRHIDTALIWRNEDEVGKGIK-- 107
Query: 332 FSEGLKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPIAMF-ENDTL 508
+ G+ R+ I++T KLWN+ H E V A+ S+ NL +EY+DLYLIH+P+A E +
Sbjct: 108 -ASGVSRDEIWVTGKLWNTDHRPELVRKAIETSIANLGVEYLDLYLIHYPVAWVPETRDV 166
Query: 509 LDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGLEXPSALQIELNLNLQQP 688
+N +DTW+ M + + GLT++IG SNF + I +I+ P A + E + LQQ
Sbjct: 167 DNNTSLIDTWKAMEELVRAGLTRNIGFSNFAPKDINKILKIASIQPYAHEFETHPYLQQQ 226
Query: 689 ELFKFCRENDIVVMAYTPFGSLFPS 763
F ++ +I V+A +P + P+
Sbjct: 227 SFVDFHKKENIKVIAASPLANTNPT 251
>UniRef50_Q9VHX4 Cluster: CG2767-PA; n=4; Endopterygota|Rep:
CG2767-PA - Drosophila melanogaster (Fruit fly)
Length = 329
Score = 140 bits (338), Expect = 6e-32
Identities = 84/220 (38%), Positives = 123/220 (55%), Gaps = 13/220 (5%)
Frame = +2
Query: 131 LQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQV 310
L ++G +PV+ +GTW + E A+ ALEAGY HIDTA YG E +
Sbjct: 7 LTFNNGEKMPVIGIGTWQAS---------DEEIETAIDAALEAGYRHIDTAPVYGNEKAI 57
Query: 311 GRALTKKFSEG-LKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPIA 487
GR L + G +KRE +FI TK+ + +V P ++KSLE+L L+YVDLYL+H P
Sbjct: 58 GRVLKRWLDAGKVKREELFIVTKVPPVSNRPHEVEPTIKKSLEDLQLDYVDLYLVHTPFT 117
Query: 488 MFENDT---LLDNVDFLDT---------WRGMIDAKKLGLTKSIGISNFNQEQIQRIIDS 631
+ N+ LD ++ W M + GLTKSIG+SNF+++Q+ R++ +
Sbjct: 118 ININEDGSFKLDKEGLMEVDVTTNHAAIWVAMEALVEKGLTKSIGVSNFSKDQVARLLKN 177
Query: 632 GLEXPSALQIELNLNLQQPELFKFCRENDIVVMAYTPFGS 751
P+ QIE ++ LQQ +L FC+ +I V AY+P GS
Sbjct: 178 CKIRPANNQIEHHVYLQQRDLVDFCKSENITVTAYSPLGS 217
>UniRef50_Q7ZA52 Cluster: Aldose reductase; n=6; Pezizomycotina|Rep:
Aldose reductase - Magnaporthe grisea (Rice blast
fungus) (Pyricularia grisea)
Length = 312
Score = 140 bits (338), Expect = 6e-32
Identities = 80/219 (36%), Positives = 127/219 (57%), Gaps = 14/219 (6%)
Frame = +2
Query: 137 LSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQVGR 316
L++G IP LGTW G KG + ++AV+ A+++GY ID AY YG E++VG+
Sbjct: 8 LNTGAKIPAFGLGTWQGD--KGVI-------KEAVLTAIKSGYRLIDGAYVYGNEEEVGQ 58
Query: 317 ALTKKFSEGL-KRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPIAMF 493
+ + S G+ KRE +F+ +K W +Y R ++ L +SL+ L L+YVDLYL+HWPI M
Sbjct: 59 GIREAISSGIVKREDLFVVSKCWATYTTRCEL--GLDQSLKLLGLDYVDLYLVHWPILMN 116
Query: 494 E--NDT-----------LLDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSG 634
ND ++ + +DTW+ M G TK++G+SN+++ +++++
Sbjct: 117 PEGNDEKFPKHADGSRDIIHTHNHVDTWKLMEKLPATGKTKAVGVSNYSKAWLEQLLPHA 176
Query: 635 LEXPSALQIELNLNLQQPELFKFCRENDIVVMAYTPFGS 751
P+ Q+E + L Q EL FC+E I +MAY+P GS
Sbjct: 177 TTVPAVNQVENHPQLPQQELVDFCKEKGIHIMAYSPLGS 215
>UniRef50_UPI0000E4A7CE Cluster: PREDICTED: similar to LOC553452
protein; n=6; Strongylocentrotus purpuratus|Rep:
PREDICTED: similar to LOC553452 protein -
Strongylocentrotus purpuratus
Length = 321
Score = 138 bits (335), Expect = 1e-31
Identities = 82/219 (37%), Positives = 123/219 (56%), Gaps = 14/219 (6%)
Frame = +2
Query: 137 LSSGGNIPVVALGTW-LGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQVG 313
L G +P++ GTW + G+V++ A++ GY HID A YG E VG
Sbjct: 10 LPGGRKLPLLGFGTWQIKPEEVGRVIET----------AIDCGYRHIDEASLYGNEKGVG 59
Query: 314 RALTKKFSEG-LKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPIA- 487
+ K +G +KRE +F+T+KLW + +V P+ R+SL +L L Y+DL+LIH P +
Sbjct: 60 DGIKAKIDDGTIKREDLFVTSKLWVTDSHPSRVEPSCRQSLSDLGLAYLDLFLIHCPTSA 119
Query: 488 --------MFENDTLL--DNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGL 637
M +N + D +D++DTWR M GL ++IG+SNF QIQR++D
Sbjct: 120 VGGKGPFPMDDNGLFIGDDTIDYVDTWRIMESLVDKGLVRAIGVSNFTVAQIQRVLDLPP 179
Query: 638 EXPSA-LQIELNLNLQQPELFKFCRENDIVVMAYTPFGS 751
+ P A +Q+E + L Q EL +FC++ I V AY+P GS
Sbjct: 180 KYPIANVQVECHPFLAQNELIEFCKKQGITVTAYSPLGS 218
>UniRef50_Q7G764 Cluster: Probable NAD(P)H-dependent oxidoreductase
1; n=32; Eukaryota|Rep: Probable NAD(P)H-dependent
oxidoreductase 1 - Oryza sativa subsp. japonica (Rice)
Length = 321
Score = 138 bits (335), Expect = 1e-31
Identities = 66/188 (35%), Positives = 110/188 (58%), Gaps = 10/188 (5%)
Frame = +2
Query: 218 TNDTEQAVIYALEAGYTHIDTAYKYGIEDQVGRALTKKFSEGL--KRESIFITTKLWNSY 391
+ DT A++ A+E GY H DTA Y E VG A+ + GL R +F+T+K+W S
Sbjct: 31 SEDTTAAMLRAIELGYRHFDTARIYATEGCVGEAVAEAVRRGLIASRADVFVTSKIWCSD 90
Query: 392 HEREQVIPALRKSLENLNLEYVDLYLIHWPIAM--------FENDTLLDNVDFLDTWRGM 547
+V+PA R++L NL ++YVDL L+HWP+++ F + +L + D WRGM
Sbjct: 91 LHAGRVVPAARETLRNLGMDYVDLLLVHWPVSLTPGNYDFPFPKEVILPSFDMEGVWRGM 150
Query: 548 IDAKKLGLTKSIGISNFNQEQIQRIIDSGLEXPSALQIELNLNLQQPELFKFCRENDIVV 727
+ +LGL ++IG+SNF+ +++++++ P+ Q+E+N QQ L + CR + +
Sbjct: 151 EECHRLGLARAIGVSNFSAKKLEQLLSLAAVRPAVNQVEVNPMWQQRTLREVCRREGVQL 210
Query: 728 MAYTPFGS 751
Y+P G+
Sbjct: 211 CGYSPLGA 218
>UniRef50_Q55FL3 Cluster: Aldo-keto reductase; n=2; Dictyostelium
discoideum AX4|Rep: Aldo-keto reductase - Dictyostelium
discoideum AX4
Length = 321
Score = 138 bits (334), Expect = 2e-31
Identities = 84/222 (37%), Positives = 124/222 (55%), Gaps = 17/222 (7%)
Frame = +2
Query: 134 QLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQVG 313
+L+ G IP + LGT+ P G+V N+ AL+ GY HID A YG E +G
Sbjct: 18 KLNDGNQIPSIGLGTYYSENP-GEVGDAINN-------ALKNGYRHIDGAAFYGNEKVIG 69
Query: 314 RALTKKFSEG-LKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPIAM 490
+L + F EG +KRE IF T+KLWNS H V+ K++E+L + Y+DLYLIHWPIA
Sbjct: 70 NSLKEIFKEGEIKREDIFYTSKLWNSCHNSNLVVKHCVKTIEDLGIGYLDLYLIHWPIA- 128
Query: 491 FEN----------------DTLLDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRI 622
FEN + ++ V +TW+ M +LGL KSIG+SNFN + + +
Sbjct: 129 FENSNPLGLTIEPLRDQNGNPIIAPVSIRETWQEMEKLVELGLVKSIGVSNFNVQNLVDL 188
Query: 623 IDSGLEXPSALQIELNLNLQQPELFKFCRENDIVVMAYTPFG 748
+ P Q+E++ L Q +L ++C + +I ++AY+P G
Sbjct: 189 LTYAKIKPVVNQVEIHPYLTQFKLQEYCDKYEIKLVAYSPLG 230
>UniRef50_Q7PLK6 Cluster: CG40064-PA; n=1; Drosophila
melanogaster|Rep: CG40064-PA - Drosophila melanogaster
(Fruit fly)
Length = 361
Score = 138 bits (333), Expect = 2e-31
Identities = 72/172 (41%), Positives = 99/172 (57%), Gaps = 12/172 (6%)
Frame = +2
Query: 236 AVIYALEAGYTHIDTAYKYGIEDQVGRALTKKFSEG-LKRESIFITTKLWNSYHEREQVI 412
AV A+E G+ H DTAY Y E ++G AL + G + RE+IF+TTKLWN++H+ V
Sbjct: 49 AVHCAIETGFRHFDTAYYYENEKEIGEALRTQIKMGNISRENIFLTTKLWNTHHDPRDVR 108
Query: 413 PALRKSLENLNLEYVDLYLIHWPIA-----------MFENDTLLDNVDFLDTWRGMIDAK 559
K LE L Y+DLYL+H+P+ M ++ +D+LDTWR M +
Sbjct: 109 RICEKQLELLGFSYIDLYLMHFPVGYKYVCDEILMPMSGDELQTVEIDYLDTWRAMENLV 168
Query: 560 KLGLTKSIGISNFNQEQIQRIIDSGLEXPSALQIELNLNLQQPELFKFCREN 715
KLG+ +SIG+SNFN EQIQRII P Q+E+ Q +L +CR N
Sbjct: 169 KLGMVRSIGLSNFNMEQIQRIIQCSSSKPVVNQVEIWPGFLQKDLVDYCRYN 220
>UniRef50_UPI00015B4912 Cluster: PREDICTED: similar to aldo-keto
reductase; n=1; Nasonia vitripennis|Rep: PREDICTED:
similar to aldo-keto reductase - Nasonia vitripennis
Length = 353
Score = 137 bits (332), Expect = 3e-31
Identities = 89/219 (40%), Positives = 121/219 (55%), Gaps = 13/219 (5%)
Frame = +2
Query: 134 QLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQVG 313
+LSSG N P+V LGT H V+ E + ALE G HIDT++ Y E+ +G
Sbjct: 32 RLSSGHNFPIVGLGT---HGLNEDVL------ETVLTGALEKGIGHIDTSFVYKNEETIG 82
Query: 314 RALTKKFSEGLKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPIAM- 490
+ L F++G KRE IF+T+KL + E V ++ SLE L L+Y+D+YLIH P A+
Sbjct: 83 KVLKDWFAKGGKREDIFVTSKLPYYDNHPESVEKYIKLSLEKLGLQYLDMYLIHAPFAVH 142
Query: 491 -----FENDTLLDNVDFLDT-------WRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSG 634
+E T D LDT W+ M K G TKSIG+SNFN+ QI I+
Sbjct: 143 HKEDSYELATNEDGSVVLDTQTDPIAVWKEMEKQVKEGRTKSIGLSNFNETQITNILKEA 202
Query: 635 LEXPSALQIELNLNLQQPELFKFCRENDIVVMAYTPFGS 751
PS LQ+E++ QQ L +FC++N I+V Y P GS
Sbjct: 203 KIKPSNLQVEVHAYHQQKPLIEFCQKNGIIVTGYAPLGS 241
>UniRef50_Q9U2J5 Cluster: Putative uncharacterized protein; n=2;
Caenorhabditis|Rep: Putative uncharacterized protein -
Caenorhabditis elegans
Length = 339
Score = 137 bits (332), Expect = 3e-31
Identities = 75/227 (33%), Positives = 124/227 (54%), Gaps = 16/227 (7%)
Frame = +2
Query: 119 IVPTLQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGI 298
I T+ L+SG +PV+ GTW PK + D ALEAGY HID+A +
Sbjct: 3 IADTVTLNSGYEMPVIGYGTW--QLPKNLAAERVRD-------ALEAGYRHIDSALSFKN 53
Query: 299 EDQVGRALTKKFS-EGLKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIH 475
+++V + ++RE +F+++K+WN+YH R + + + + LE Y+DL +IH
Sbjct: 54 QEEVAAGIKDWCKIRKVRREELFLSSKIWNTYHSRNRCMQQIDEMLEIFETTYMDLIVIH 113
Query: 476 WPIAMFEND---------------TLLDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQ 610
WP E++ +VD+L+TW+ + DA + G +SIG++NFN Q
Sbjct: 114 WPFGWAEDEPPGERGLWPRGANGKMRYSDVDYLETWKALEDAHRSGKIRSIGLANFNIGQ 173
Query: 611 IQRIIDSGLEXPSALQIELNLNLQQPELFKFCRENDIVVMAYTPFGS 751
++++ GL P+ LQ+E+N L Q E+ +FCRE I++ A+ G+
Sbjct: 174 VEQVWTKGLIKPAVLQVEMNPFLDQEEIRQFCREKGIILTAFMLTGN 220
>UniRef50_P23901 Cluster: Aldose reductase; n=9; Poaceae|Rep: Aldose
reductase - Hordeum vulgare (Barley)
Length = 320
Score = 137 bits (332), Expect = 3e-31
Identities = 73/212 (34%), Positives = 120/212 (56%), Gaps = 7/212 (3%)
Frame = +2
Query: 137 LSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYAL-EAGYTHIDTAYKYGIEDQVG 313
L SG +P V LGTW + +DT +V A+ EAGY H+DTA +YG+E +VG
Sbjct: 18 LKSGHAMPAVGLGTW----------RAGSDTAHSVRTAITEAGYRHVDTAAEYGVEKEVG 67
Query: 314 RALTKKFSEGLKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPIAMF 493
+ L G+ R+ +F+T+K+W + E+V PAL +L++L L+Y+DLY IHWP +
Sbjct: 68 KGLKAAMEAGIDRKDLFVTSKIWCTNLAPERVRPALENTLKDLQLDYIDLYHIHWPFRLK 127
Query: 494 ENDTL------LDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGLEXPSAL 655
+ + + D W+ M + K GL K IG+ N+ ++ R++ S P+
Sbjct: 128 DGAHMPPEAGEVLEFDMEGVWKEMENLVKDGLVKDIGVCNYTVTKLNRLLRSAKIPPAVC 187
Query: 656 QIELNLNLQQPELFKFCRENDIVVMAYTPFGS 751
Q+E++ + ++F+ C+++ I V AY+P GS
Sbjct: 188 QMEMHPGWKNDKIFEACKKHGIHVTAYSPLGS 219
>UniRef50_A3C1Z7 Cluster: Putative uncharacterized protein; n=2;
Oryza sativa (japonica cultivar-group)|Rep: Putative
uncharacterized protein - Oryza sativa subsp. japonica
(Rice)
Length = 288
Score = 137 bits (331), Expect = 4e-31
Identities = 78/221 (35%), Positives = 129/221 (58%), Gaps = 12/221 (5%)
Frame = +2
Query: 122 VPTLQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIE 301
+P LSSG +P V +GT P G T + V+ A+EAGY H DTA Y E
Sbjct: 1 MPEAALSSGKPMPRVGMGT--ASFPLGATDPST--VKDVVLRAIEAGYRHFDTAAVYQTE 56
Query: 302 DQVGRALTKKFSEGL--KRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIH 475
+G A+ + GL R+ ++IT+KLW ++ V+P+LR++L + +EY+DLYLIH
Sbjct: 57 AILGDAVAEAVRAGLVASRDELYITSKLWVAHAHPGHVLPSLRRALRKMQMEYLDLYLIH 116
Query: 476 WPIAM----------FENDTLLDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRII 625
+P++M + D L+ +D W+ M + ++LGLTK+IG+SNF+ ++++ ++
Sbjct: 117 FPVSMRLAEDPESMTYSKDDLV-MMDMEGVWKEMEECQRLGLTKAIGVSNFSCKKLETLL 175
Query: 626 DSGLEXPSALQIELNLNLQQPELFKFCRENDIVVMAYTPFG 748
P+A Q+E++ +Q +L +FC+E I + AY+P G
Sbjct: 176 SFATISPAANQVEVHPYCRQNKLREFCKEKGIQLCAYSPLG 216
>UniRef50_Q01HB5 Cluster: OSIGBa0136O08-OSIGBa0153H12.9 protein;
n=4; Oryza sativa|Rep: OSIGBa0136O08-OSIGBa0153H12.9
protein - Oryza sativa (Rice)
Length = 337
Score = 136 bits (330), Expect = 5e-31
Identities = 80/228 (35%), Positives = 122/228 (53%), Gaps = 13/228 (5%)
Frame = +2
Query: 107 SADLIVPTLQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAY 286
+A VP + L+SG +PV+ GT P D + +A+ GY H+DTA
Sbjct: 15 AAATAVPCVTLNSGHAMPVLGFGTGSSTPPA--------DLAATIAHAVRLGYRHLDTAA 66
Query: 287 KYGIEDQVGRALTKKFSEGL--KRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVD 460
YG E VG A+ + G R +F+TTKL + +V+ ALR+SL L L+YVD
Sbjct: 67 VYGTEGAVGAAVAEAVRCGAVASRGELFVTTKLSMADAHPPRVVAALRESLSRLGLDYVD 126
Query: 461 LYLIHWPIAMFENDTL-----------LDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQE 607
L+LIHWP+A+ + D L D WRGM + +LGL +SIG+SNF+
Sbjct: 127 LFLIHWPVAIGKKDAAGELTWDDLSRGLVPFDMEGVWRGMEECHRLGLARSIGVSNFSAA 186
Query: 608 QIQRIIDSGLEXPSALQIELNLNLQQPELFKFCRENDIVVMAYTPFGS 751
++ R++ P+ Q+E+N+ +Q ++ + C E +VV AY+P G+
Sbjct: 187 KMSRLLALAAVPPAVNQVEMNVGWRQEKVREVCGEGGVVVAAYSPLGA 234
>UniRef50_Q1YPE5 Cluster: Aldehyde reductase; n=7; Bacteria|Rep:
Aldehyde reductase - gamma proteobacterium HTCC2207
Length = 330
Score = 136 bits (329), Expect = 7e-31
Identities = 83/231 (35%), Positives = 127/231 (54%), Gaps = 20/231 (8%)
Frame = +2
Query: 122 VPTLQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIE 301
VP +++SS ++P V LG W K+ Q + QAV A++ GY H+D+A YG E
Sbjct: 7 VPGVKVSSK-SMPAVGLGLW-------KITQ--DSAAQAVYEAIKVGYRHLDSAADYGNE 56
Query: 302 DQVGRALTKKFSEGL-KRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHW 478
QVG + + +EGL RE ++ITTKLWN+YH E V A R+S+++L L+Y+DLYL+H+
Sbjct: 57 QQVGEGIARAIAEGLCSREELWITTKLWNTYHRAEHVEAACRRSMDDLGLDYIDLYLVHF 116
Query: 479 PIAM--------------FENDT-----LLDNVDFLDTWRGMIDAKKLGLTKSIGISNFN 601
PIA+ F++ LD V +TW M + GL + IG+ N++
Sbjct: 117 PIALRYVDFNDRYPAEWIFDHSAEDPAMELDQVPLSETWGAMEQLVESGLVRQIGVCNYS 176
Query: 602 QEQIQRIIDSGLEXPSALQIELNLNLQQPELFKFCRENDIVVMAYTPFGSL 754
+ ++ P+ LQIE + L Q L + R ++ V A++P GSL
Sbjct: 177 AVLLHDLMSYARIKPAMLQIESHPYLTQEALLRTARSYNMAVTAFSPLGSL 227
>UniRef50_P06632 Cluster: 2,5-diketo-D-gluconic acid reductase A;
n=8; Actinomycetales|Rep: 2,5-diketo-D-gluconic acid
reductase A - Corynebacterium sp. (strain ATCC 31090)
Length = 278
Score = 136 bits (328), Expect = 9e-31
Identities = 78/211 (36%), Positives = 120/211 (56%)
Frame = +2
Query: 116 LIVPTLQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYG 295
+ VP++ L+ G +IP + G + KV DT++AV ALE GY HIDTA YG
Sbjct: 1 MTVPSIVLNDGNSIPQLGYGVF-------KVPPA--DTQRAVEEALEVGYRHIDTAAIYG 51
Query: 296 IEDQVGRALTKKFSEGLKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIH 475
E+ VG A+ + G+ R+ +FITTKLWN H+ ++ A+ +SL L L+ VDLYL+H
Sbjct: 52 NEEGVGAAIA---ASGIARDDLFITTKLWNDRHDGDEPAAAIAESLAKLALDQVDLYLVH 108
Query: 476 WPIAMFENDTLLDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGLEXPSAL 655
WP +N ++ W MI+ + GLT+SIG+SN ++RI+ + P+
Sbjct: 109 WPTPAADN--------YVHAWEKMIELRAAGLTRSIGVSNHLVPHLERIVAATGVVPAVN 160
Query: 656 QIELNLNLQQPELFKFCRENDIVVMAYTPFG 748
QIEL+ QQ E+ + +D+ + ++ P G
Sbjct: 161 QIELHPAYQQREITDWAAAHDVKIESWGPLG 191
>UniRef50_Q03TW0 Cluster: Aldo/keto reductase of diketogulonate
reductase family; n=1; Lactobacillus brevis ATCC
367|Rep: Aldo/keto reductase of diketogulonate reductase
family - Lactobacillus brevis (strain ATCC 367 / JCM
1170)
Length = 293
Score = 135 bits (327), Expect = 1e-30
Identities = 78/209 (37%), Positives = 114/209 (54%)
Frame = +2
Query: 122 VPTLQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIE 301
+P L +++G IP + LG + V DT+ A+ +AL AGY HIDTA YG E
Sbjct: 11 IPDLPMNNGHQIPQLGLGVFQ--------VDNAEDTKNAIKWALAAGYRHIDTAAYYGNE 62
Query: 302 DQVGRALTKKFSEGLKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWP 481
VG A+ + + R+ IF+T+KLWNS ++ A +++L+ L L+Y+DLYLIHWP
Sbjct: 63 QWVGEAIRES---DVPRDQIFVTSKLWNSVRGYDETQAAFQETLDKLGLDYLDLYLIHWP 119
Query: 482 IAMFENDTLLDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGLEXPSALQI 661
+LD+WR M D K G K+IG+SNFNQ Q+ I+ G P QI
Sbjct: 120 AP-----------GYLDSWRAMEDLYKAGKIKNIGVSNFNQTQMADILAHGTVKPVVDQI 168
Query: 662 ELNLNLQQPELFKFCRENDIVVMAYTPFG 748
E + QQ ++ + I+ A++P G
Sbjct: 169 ETHPYFQQNDMHAYLESQGILHEAWSPLG 197
>UniRef50_Q0PGJ6 Cluster: Aldo-keto reductase; n=32;
Magnoliophyta|Rep: Aldo-keto reductase - Arabidopsis
thaliana (Mouse-ear cress)
Length = 315
Score = 135 bits (327), Expect = 1e-30
Identities = 78/213 (36%), Positives = 121/213 (56%), Gaps = 7/213 (3%)
Frame = +2
Query: 134 QLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQVG 313
+L++G P V LGTW G V AV A++ GY HID A YG E ++G
Sbjct: 9 KLNTGAKFPSVGLGTW--QASPGLV-------GDAVAAAVKIGYRHIDCAQIYGNEKEIG 59
Query: 314 RALTKKFSEGL-KRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPIAM 490
L K F + + KRE +FIT+KLW + H+ + V AL ++L++L LEYVDLYLIHWP +
Sbjct: 60 AVLKKLFEDRVVKREDLFITSKLWCTDHDPQDVPEALNRTLKDLQLEYVDLYLIHWPARI 119
Query: 491 ------FENDTLLDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGLEXPSA 652
+ + LL VD TW+ M G ++IG+SNF+ +++ +++ P+
Sbjct: 120 KKGSVGIKPENLLP-VDIPSTWKAMEALYDSGKARAIGVSNFSTKKLADLLELARVPPAV 178
Query: 653 LQIELNLNLQQPELFKFCRENDIVVMAYTPFGS 751
Q+E + + +Q +L +FC+ + + AY+P GS
Sbjct: 179 NQVECHPSWRQTKLQEFCKSKGVHLSAYSPLGS 211
>UniRef50_UPI0000E45E29 Cluster: PREDICTED: similar to aldose
reductase; n=1; Strongylocentrotus purpuratus|Rep:
PREDICTED: similar to aldose reductase -
Strongylocentrotus purpuratus
Length = 274
Score = 134 bits (324), Expect = 3e-30
Identities = 74/187 (39%), Positives = 111/187 (59%), Gaps = 1/187 (0%)
Frame = +2
Query: 230 EQAVIYALEAGYTHIDTAYKYGIEDQVGRALTKKFSEGL-KRESIFITTKLWNSYHEREQ 406
E AV A++ GY HID A+ YG E +VG L +KF + KRE IFIT+KLWN+ H +
Sbjct: 13 EAAVKAAIDCGYRHIDCAHVYGNEAEVGAGLKEKFDANVVKREDIFITSKLWNNKHHPDD 72
Query: 407 VIPALRKSLENLNLEYVDLYLIHWPIAMFENDTLLDNVDFLDTWRGMIDAKKLGLTKSIG 586
V A +L+NL L YVDLYL+HWP+A + L+ + G K+IG
Sbjct: 73 VEQACDITLKNLQLSYVDLYLMHWPMAYQAMEKLVTS----------------GKCKAIG 116
Query: 587 ISNFNQEQIQRIIDSGLEXPSALQIELNLNLQQPELFKFCRENDIVVMAYTPFGSLFPSK 766
+SNF+ + ++R+I+ P+ LQ+EL+ L Q +L +FC+E+++ V AY+P G+
Sbjct: 117 LSNFSMKMMKRVIEKATIQPANLQVELHPLLTQEKLIEFCKEHNMTVTAYSPLGAPDRPW 176
Query: 767 AQPDAPR 787
+ D P+
Sbjct: 177 VKDDDPK 183
>UniRef50_A1UEC5 Cluster: 2,5-didehydrogluconate reductase; n=20;
Corynebacterineae|Rep: 2,5-didehydrogluconate reductase
- Mycobacterium sp. (strain KMS)
Length = 283
Score = 134 bits (324), Expect = 3e-30
Identities = 85/209 (40%), Positives = 118/209 (56%)
Frame = +2
Query: 122 VPTLQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIE 301
+P++ L+ G +IPV+ LG G++ + + E++V ALEAGY IDTA YG E
Sbjct: 11 IPSVSLNDGHSIPVLGLGV-------GELSEA--EAERSVAAALEAGYRLIDTAAVYGNE 61
Query: 302 DQVGRALTKKFSEGLKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWP 481
VGRA+ + G+ RE I++TTKL + A R SLE L L+YVDLYLIHWP
Sbjct: 62 AAVGRAVN---ASGIPREEIYVTTKLAVADQGFGTSQDAARASLERLGLDYVDLYLIHWP 118
Query: 482 IAMFENDTLLDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGLEXPSALQI 661
D+ ++D+W G++ AK+ G+ +SIG+ NFN E + IID P+ QI
Sbjct: 119 AG--------DHGKYIDSWGGLMKAKQDGVARSIGVCNFNAEHLSNIIDLSFFTPAINQI 170
Query: 662 ELNLNLQQPELFKFCRENDIVVMAYTPFG 748
EL+ L Q EL + IV AY P G
Sbjct: 171 ELHPLLNQAELREVNAGYGIVTEAYGPLG 199
>UniRef50_Q7QVQ9 Cluster: GLP_302_44328_45269; n=1; Giardia lamblia
ATCC 50803|Rep: GLP_302_44328_45269 - Giardia lamblia
ATCC 50803
Length = 313
Score = 134 bits (324), Expect = 3e-30
Identities = 73/211 (34%), Positives = 110/211 (52%), Gaps = 15/211 (7%)
Frame = +2
Query: 230 EQAVIYALEAGYTHIDTAYKYGIEDQVGRALTKKF---SEGLKRESIFITTKLWNSYHER 400
+ AV AL GY HID AY Y E+ +GRA K F S G+KRE ++IT+KLWN H
Sbjct: 20 QTAVETALMTGYRHIDCAYVYQNEEAIGRAFGKIFKDASSGIKREDVWITSKLWNYNHRP 79
Query: 401 EQVIPALRKSLENLNLEYVDLYLIHWPIAMFEND------------TLLDNVDFLDTWRG 544
E V +K++ +L ++Y+DL+L+HWP+A ND +L+ V DTWR
Sbjct: 80 ELVREQCKKTMSDLQVDYLDLFLVHWPLAFVRNDVGDLFPKDAEGRAMLEKVPLADTWRA 139
Query: 545 MIDAKKLGLTKSIGISNFNQEQIQRIIDSGLEXPSALQIELNLNLQQPELFKFCRENDIV 724
M + GL K IG+SN+ + +++ P QIE++ KFC +N I
Sbjct: 140 MEQLVEEGLVKHIGVSNYTVPLLADLLNYAKIKPLVNQIEIHPWHPNDATVKFCLDNGIG 199
Query: 725 VMAYTPFGSLFPSKAQPDAPRRGLTMNVSSV 817
V AY+P G + P ++ + + ++
Sbjct: 200 VTAYSPMGGSYADPRDPSGTQKNVILECKTL 230
>UniRef50_Q1U9L6 Cluster: 2,5-didehydrogluconate reductase; n=3;
Lactobacillus|Rep: 2,5-didehydrogluconate reductase -
Lactobacillus reuteri 100-23
Length = 288
Score = 133 bits (321), Expect = 7e-30
Identities = 78/209 (37%), Positives = 115/209 (55%), Gaps = 2/209 (0%)
Frame = +2
Query: 128 TLQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQ 307
T L++G IP V GT+ R V EQAV A+E GY HIDTA YG E+
Sbjct: 10 TFNLNNGVKIPCVGYGTF---RTPADVA------EQAVKEAIETGYRHIDTAAVYGNEEA 60
Query: 308 VGRALTKKFSEGLKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPI- 484
VG+ + G+KRE +F+T+KLWN+ EQ A +++L+ L ++Y+DLYLIHWP
Sbjct: 61 VGKGIK---DSGIKREDLFVTSKLWNTNRGYEQTKKAFQETLDRLQMDYLDLYLIHWPAN 117
Query: 485 -AMFENDTLLDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGLEXPSALQI 661
F +D N +TWR M D G ++IG+SNF I ++ + P+ QI
Sbjct: 118 EKQFGDDAAKINA---ETWRAMEDLYNEGKIRAIGVSNFMPHHIAELMKTAKVAPAVDQI 174
Query: 662 ELNLNLQQPELFKFCRENDIVVMAYTPFG 748
E++ E+ K+ + ++I+V A+ P G
Sbjct: 175 EVHPGWPHTEVVKYLQAHNILVEAWAPLG 203
>UniRef50_Q6RZX1 Cluster: Gld1; n=22; Pezizomycotina|Rep: Gld1 -
Trichoderma atroviride (Hypocrea atroviridis)
Length = 327
Score = 133 bits (321), Expect = 7e-30
Identities = 80/226 (35%), Positives = 122/226 (53%), Gaps = 18/226 (7%)
Frame = +2
Query: 128 TLQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQ 307
T L++G IP V GT+ KG +T AV AL+ GY H+D A+ Y ED+
Sbjct: 14 TYTLNTGAKIPAVGFGTFANEGAKG-------ETYAAVTKALDVGYRHLDCAWFYLNEDE 66
Query: 308 VGRALTKKFSE--GLKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWP 481
VG A+ + + R+ +FI TK+WN HE E V + + S ENL ++Y+DL+L+HWP
Sbjct: 67 VGDAIRDFLARRPDVTRKDLFICTKVWNHLHEPEDVKWSAKNSCENLKVDYIDLFLVHWP 126
Query: 482 IAMFE----------------NDTLLDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQI 613
IA + N L +N + TWR M + G+ K+IG+SN+ +
Sbjct: 127 IAAEKNADRTVKIGPDGKYVINKALTENPE--PTWRAMEELVDSGIVKAIGVSNWTIPGL 184
Query: 614 QRIIDSGLEXPSALQIELNLNLQQPELFKFCRENDIVVMAYTPFGS 751
+++++ P+ QIE++ L EL +FC +NDI+ AY+P GS
Sbjct: 185 KQLLEFARIKPAVNQIEIHPFLPNTELVEFCFQNDILPEAYSPLGS 230
>UniRef50_Q7WSY4 Cluster: Putative aldo-keto reductase; n=1;
Propionibacterium freudenreichii subsp. shermanii|Rep:
Putative aldo-keto reductase - Propionibacterium
freudenreichii subsp. shermanii
Length = 280
Score = 132 bits (320), Expect = 9e-30
Identities = 78/208 (37%), Positives = 118/208 (56%)
Frame = +2
Query: 125 PTLQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIED 304
PT++LS G +P++ +GTW KG+ + AV A+E GY +DTA YG E+
Sbjct: 9 PTVELSGGTRMPMLGMGTW---PLKGE------ECRAAVASAIEQGYRLVDTAEAYGNEE 59
Query: 305 QVGRALTKKFSEGLKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPI 484
VG+A+ + G R IF+TTK +H R+ V AL SLE L L+YVDL+L+HWP+
Sbjct: 60 AVGKAVREA---GPDRAEIFVTTKFSKQWHSRKGVHEALEHSLERLGLDYVDLFLMHWPM 116
Query: 485 AMFENDTLLDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGLEXPSALQIE 664
++D +RGM++ K+ GL K+IG+SNF + +I G+ P QI+
Sbjct: 117 P--------GEGSYVDAYRGMVELKEQGLAKAIGVSNFKVHHLDDLITEGM-TPEVNQIQ 167
Query: 665 LNLNLQQPELFKFCRENDIVVMAYTPFG 748
L+ + + E+ F +DIV A++P G
Sbjct: 168 LDPSRPRLEVRDFLDNHDIVTEAWSPLG 195
>UniRef50_Q7G765 Cluster: Probable NAD(P)H-dependent oxidoreductase
2; n=6; Magnoliophyta|Rep: Probable NAD(P)H-dependent
oxidoreductase 2 - Oryza sativa subsp. japonica (Rice)
Length = 322
Score = 132 bits (320), Expect = 9e-30
Identities = 65/188 (34%), Positives = 107/188 (56%), Gaps = 10/188 (5%)
Frame = +2
Query: 218 TNDTEQAVIYALEAGYTHIDTAYKYGIEDQVGRALTKKFSEGL--KRESIFITTKLWNSY 391
+ +T A++ A+E GY H DTA Y E V A+ + GL R +F+T+KLW S
Sbjct: 33 SEETTAALLRAIELGYRHFDTARLYATEGCVSEAVAEAVRRGLVASRADVFVTSKLWCSD 92
Query: 392 HEREQVIPALRKSLENLNLEYVDLYLIHWPIAM--------FENDTLLDNVDFLDTWRGM 547
+V+PA R++L NL ++YVDL L+HWP + F + + D WRGM
Sbjct: 93 LHAGRVVPAARETLRNLGMDYVDLLLVHWPATVAPGSYDFPFPKEEMAPAFDMEGVWRGM 152
Query: 548 IDAKKLGLTKSIGISNFNQEQIQRIIDSGLEXPSALQIELNLNLQQPELFKFCRENDIVV 727
+ +LGL ++IG+SNF+ +++++++ + P+A Q+E+N QQ L + CR + +
Sbjct: 153 EECHRLGLARAIGVSNFSAKKLEQLLSFAVVRPAANQVEMNPMWQQRTLREVCRREGVQL 212
Query: 728 MAYTPFGS 751
Y+P G+
Sbjct: 213 CGYSPLGA 220
>UniRef50_A7CWF9 Cluster: Aldehyde reductase; n=2; Bacteria|Rep:
Aldehyde reductase - Opitutaceae bacterium TAV2
Length = 347
Score = 132 bits (319), Expect = 1e-29
Identities = 79/233 (33%), Positives = 119/233 (51%), Gaps = 14/233 (6%)
Frame = +2
Query: 122 VPTLQLSSGGNIPVVALGTW-LGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGI 298
+P L+SG +P + +GT+ H G+V +V A E GY H D A Y
Sbjct: 16 IPQRTLASGARMPAIGMGTFGSDHAAPGEVAA-------SVYAAAELGYRHFDCAAVYSN 68
Query: 299 EDQVGRALTKKFSE--GLKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLI 472
E ++G + + G++RE ++IT+KLWN H VIPA KSL +L L+Y+DLYLI
Sbjct: 69 EREIGATFRRILTSNTGIRREDLWITSKLWNDKHAEADVIPAFEKSLRDLGLDYLDLYLI 128
Query: 473 HWPIAMFE------NDTLLD-----NVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQR 619
HWP F + D + +F+ TWR + GL + IG SN ++Q
Sbjct: 129 HWPFPNFHPPGCDVSSRSPDARPYIHAEFMKTWRQLETLHDRGLVRHIGTSNMTIAKLQL 188
Query: 620 IIDSGLEXPSALQIELNLNLQQPELFKFCRENDIVVMAYTPFGSLFPSKAQPD 778
++ P+ ++EL+ + QQP LF + R +IV + Y P GS P + + D
Sbjct: 189 LLRDARVRPAVNEMELHPHFQQPALFDYVRVRNIVPVGYCPLGS--PGRPERD 239
>UniRef50_Q9FJK0 Cluster: Aldose reductase-like protein; n=3; core
eudicotyledons|Rep: Aldose reductase-like protein -
Arabidopsis thaliana (Mouse-ear cress)
Length = 316
Score = 132 bits (319), Expect = 1e-29
Identities = 75/214 (35%), Positives = 123/214 (57%), Gaps = 9/214 (4%)
Frame = +2
Query: 134 QLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQVG 313
+L G IP++ +GT+ + + T AV A++ GY H DTA YG E+ +G
Sbjct: 7 RLRCGETIPLLGMGTYCPQKDR-------ESTISAVHQAIKIGYRHFDTAKIYGSEEALG 59
Query: 314 RALTKKFSEG-LKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPIAM 490
AL + S G ++R+ +F+T+KLW+S H I AL ++L+ + L+Y+D YL+HWPI +
Sbjct: 60 TALGQAISYGTVQRDDLFVTSKLWSSDHH--DPISALIQTLKTMGLDYLDNYLVHWPIKL 117
Query: 491 F--------ENDTLLDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGLEXP 646
+ D ++ +TW+GM ++GL +SIG+SNF+ ++I ++D P
Sbjct: 118 KPGVSEPIPKEDEFEKDLGIEETWQGMERCLEMGLCRSIGVSNFSSKKIFDLLDFASVSP 177
Query: 647 SALQIELNLNLQQPELFKFCRENDIVVMAYTPFG 748
S Q+E++ +Q +L K C EN+I V Y+P G
Sbjct: 178 SVNQVEMHPLWRQRKLRKVCEENNIHVSGYSPLG 211
>UniRef50_Q4PAT5 Cluster: Putative uncharacterized protein; n=1;
Ustilago maydis|Rep: Putative uncharacterized protein -
Ustilago maydis (Smut fungus)
Length = 700
Score = 132 bits (319), Expect = 1e-29
Identities = 76/221 (34%), Positives = 119/221 (53%), Gaps = 16/221 (7%)
Frame = +2
Query: 137 LSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQVGR 316
L++G IP + GTW K Q T AV +A++ GY HID A+ Y ED V
Sbjct: 14 LANGAQIPKLGFGTW-----KMSKEQAT----PAVAHAIKTGYRHIDCAWAYRNEDAVAA 64
Query: 317 ALTKKFSEGLKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPIAMFE 496
+ K G+ R +++T+KLWNS+H E V AL SL++L +Y+DLYL+HWP+A
Sbjct: 65 GIKKA---GVPRSQLWLTSKLWNSFHHPEHVEKALDASLKDLGTDYLDLYLMHWPVAFLN 121
Query: 497 N-DTLLDNV---------------DFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIID 628
+ +++ ++ DF+ T+R M + K G ++IG+SNFN + ++D
Sbjct: 122 SKGSMVPSIRSTGGHPVESEDLSRDFMATYRVMEEMVKKGKVRNIGVSNFNIRRTSEVVD 181
Query: 629 SGLEXPSALQIELNLNLQQPELFKFCRENDIVVMAYTPFGS 751
P Q+E+NL + EL + + + + AY+PFGS
Sbjct: 182 EASIKPVVNQVEVNLGVHNEELRNYAHAHGVTLQAYSPFGS 222
>UniRef50_Q22352 Cluster: Putative uncharacterized protein T08H10.1;
n=2; Caenorhabditis|Rep: Putative uncharacterized
protein T08H10.1 - Caenorhabditis elegans
Length = 333
Score = 132 bits (318), Expect = 2e-29
Identities = 84/235 (35%), Positives = 124/235 (52%), Gaps = 14/235 (5%)
Frame = +2
Query: 116 LIVPTLQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIY--ALEAGYTHIDTAYK 289
+ V ++ L++G +P+ LGTW QV ++ E V AL+AGY IDTA+
Sbjct: 1 MTVDSIPLNTGAQLPLFGLGTW----------QVKDEAELTVALRAALDAGYRLIDTAHL 50
Query: 290 YGIEDQVGRALTKKFSEG-LKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLY 466
Y E +G+ L + S G LKRE IF+T+KL + H E V + L+ L LEY+DLY
Sbjct: 51 YQNEHIIGKVLHEYISSGKLKREDIFVTSKLPFTAHAPEDVPKCVESQLKALQLEYIDLY 110
Query: 467 LIHWPIA----------MFENDTL-LDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQI 613
LIH P + EN L + + +DTWR + K G K++G+SNF+ Q+
Sbjct: 111 LIHCPFPFKHQEGSFAPLMENGELAVTEIAHIDTWRALEKLYKEGKLKALGVSNFSCNQL 170
Query: 614 QRIIDSGLEXPSALQIELNLNLQQPELFKFCRENDIVVMAYTPFGSLFPSKAQPD 778
Q + D+ P+ Q+E ++ Q EL C++ + V AY P GS A+PD
Sbjct: 171 QALYDAAEVKPANQQVECHIYWPQQELRALCKKLGVTVTAYAPLGSPGRKAARPD 225
>UniRef50_A6RKL9 Cluster: Putative uncharacterized protein; n=3;
Sclerotiniaceae|Rep: Putative uncharacterized protein -
Botryotinia fuckeliana B05.10
Length = 360
Score = 132 bits (318), Expect = 2e-29
Identities = 81/211 (38%), Positives = 115/211 (54%), Gaps = 2/211 (0%)
Frame = +2
Query: 158 PVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQVGRALTKKFS 337
P++ GTW V N TE AV YA+E GY ID A YG E VGR + +
Sbjct: 40 PLIGFGTW------NLKVSPENTTE-AVAYAIEIGYRQIDCAAVYGNEVAVGRGIEEGLK 92
Query: 338 E-GLKRESIFITTKLWNSYH-EREQVIPALRKSLENLNLEYVDLYLIHWPIAMFENDTLL 511
GLKRE I++T+KLWN +H E V L ++L++L LEY+DLYLIHWPI N
Sbjct: 93 RAGLKREDIWVTSKLWNDHHGSYENVEKGLNQTLQDLGLEYLDLYLIHWPIGFSSNGA-- 150
Query: 512 DNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGLEXPSALQIELNLNLQQPE 691
N+D + T++ MI K +IG+SNF+ Q++ ++ +G P Q+EL+ LQQ
Sbjct: 151 KNLDHVQTYKSMISLPK-SRVLNIGVSNFSPLQLKNVVSTG-TIPYMHQMELHPYLQQSA 208
Query: 692 LFKFCRENDIVVMAYTPFGSLFPSKAQPDAP 784
+ I + AY+P G+ P+ +P
Sbjct: 209 WVATHKALGIKMTAYSPLGNTNPTYHSSTSP 239
>UniRef50_A5VK30 Cluster: 2,5-didehydrogluconate reductase; n=2;
Lactobacillus reuteri|Rep: 2,5-didehydrogluconate
reductase - Lactobacillus reuteri F275
Length = 300
Score = 131 bits (317), Expect = 2e-29
Identities = 77/211 (36%), Positives = 121/211 (57%), Gaps = 2/211 (0%)
Frame = +2
Query: 125 PTLQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIED 304
P ++L++G IP + LG W K + + T+Q V A+ Y IDTA +YG E
Sbjct: 11 PKIKLNNGHLIPQLGLGVW-----KASLAE----TQQMVKEAIMNDYVLIDTAKQYGNEA 61
Query: 305 QVGRALTKKF-SEGLKRESIFITTKLWNSYH-EREQVIPALRKSLENLNLEYVDLYLIHW 478
VG+ + F + G KR+SIF+TTK++N + +++ A+ + L+ L YVDL L+HW
Sbjct: 62 AVGQGIQDGFKATGRKRDSIFLTTKIFNGDQGDYDKLRQAVNEQLKKLQTNYVDLLLLHW 121
Query: 479 PIAMFENDTLLDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGLEXPSALQ 658
P+ N + ++WR + D K G K+IG+ NFN E++ ++D P+ Q
Sbjct: 122 PV----------NDKYNESWRALEDIYKDGQAKAIGVCNFNVERMTDLLDHAKIKPAINQ 171
Query: 659 IELNLNLQQPELFKFCRENDIVVMAYTPFGS 751
IE N + QP++ KFCRENDI + A++P G+
Sbjct: 172 IEFNPLIHQPKIVKFCRENDIQLEAWSPLGN 202
>UniRef50_A2EHN6 Cluster: Oxidoreductase, aldo/keto reductase family
protein; n=10; Trichomonas vaginalis|Rep:
Oxidoreductase, aldo/keto reductase family protein -
Trichomonas vaginalis G3
Length = 312
Score = 131 bits (317), Expect = 2e-29
Identities = 79/214 (36%), Positives = 124/214 (57%), Gaps = 16/214 (7%)
Frame = +2
Query: 155 IPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALE-AGYTHIDTAYKYGIEDQVGRALTKK 331
IP + GT+L + P + A+ YA+E G HIDTA+ Y ++ +G L +
Sbjct: 3 IPQLGFGTYLANDPA--------KLKAALHYAIEECGVRHIDTAFAYYNQNVIGETLKEI 54
Query: 332 FSEG-LKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPIAM----FE 496
F++G +KRE +FITTKLW ++H ++ V P L ++L L L YVDL+LIH PIA +
Sbjct: 55 FAKGKIKREDMFITTKLWCTHHRKDLVEPELHENLAQLQLSYVDLFLIHQPIAFKSLPAK 114
Query: 497 NDTLL----------DNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGLEXP 646
+ T++ + +D L+T+ M + +K GLT+ IG+SNF+ EQ++RI + P
Sbjct: 115 DGTMMPKDEKGKIQYEQIDILETYHAMEECQKKGLTRHIGVSNFSIEQLERIWFNCEIKP 174
Query: 647 SALQIELNLNLQQPELFKFCRENDIVVMAYTPFG 748
A Q+E N+ Q L +C ++I +MA+T G
Sbjct: 175 YANQVECNIYRQFKPLLSYCESHNIYLMAHTTIG 208
>UniRef50_P28475 Cluster: NADP-dependent D-sorbitol-6-phosphate
dehydrogenase; n=71; Magnoliophyta|Rep: NADP-dependent
D-sorbitol-6-phosphate dehydrogenase - Malus domestica
(Apple) (Malus sylvestris)
Length = 310
Score = 130 bits (315), Expect = 4e-29
Identities = 78/228 (34%), Positives = 119/228 (52%), Gaps = 15/228 (6%)
Frame = +2
Query: 128 TLQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQ 307
T+ LSSG +PV+ LG W + ++ ++ ++ A++ GY H D A Y E
Sbjct: 3 TVTLSSGYEMPVIGLGLWRLEK---------DELKEVILNAIKIGYRHFDCAAHYKSEAD 53
Query: 308 VGRALTKKFSEGL-KRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPI 484
VG AL + F GL KRE +FITTK+WNS H V+ A + SLE L ++Y+DLYL+H+P+
Sbjct: 54 VGEALAEAFKTGLVKREELFITTKIWNSDHGH--VVEACKNSLEKLQIDYLDLYLVHYPM 111
Query: 485 -----------AMFENDTLLD---NVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRI 622
++ D +LD + TW GM LGL +SIG+SN+ +
Sbjct: 112 PTKHNAIGKTASLLGEDKVLDIDVTISLQQTWEGMEKTVSLGLVRSIGLSNYELFLTRDC 171
Query: 623 IDSGLEXPSALQIELNLNLQQPELFKFCRENDIVVMAYTPFGSLFPSK 766
+ P+ Q E + Q+ L KFC ++ ++ A+TP G +K
Sbjct: 172 LAYSKIKPAVSQFETHPYFQRDSLVKFCMKHGVLPTAHTPLGGAAANK 219
>UniRef50_Q41E86 Cluster: 2,5-didehydrogluconate reductase; n=2;
Bacteria|Rep: 2,5-didehydrogluconate reductase -
Exiguobacterium sibiricum 255-15
Length = 274
Score = 130 bits (313), Expect = 6e-29
Identities = 71/170 (41%), Positives = 99/170 (58%)
Frame = +2
Query: 233 QAVIYALEAGYTHIDTAYKYGIEDQVGRALTKKFSEGLKRESIFITTKLWNSYHEREQVI 412
+AV AL GY IDTA Y E VGRAL G+ RE IF+TTK+WN E+ +
Sbjct: 29 EAVREALRVGYRSIDTAMIYENEAGVGRALK---DSGIPREDIFLTTKVWNKDQGYERTL 85
Query: 413 PALRKSLENLNLEYVDLYLIHWPIAMFENDTLLDNVDFLDTWRGMIDAKKLGLTKSIGIS 592
A SL+ L ++YVDLYLIHWP+ D ++DTWR + + G K+IG+S
Sbjct: 86 AAFETSLQKLGVDYVDLYLIHWPMP--------DEDLYMDTWRALEQLYRDGKAKAIGVS 137
Query: 593 NFNQEQIQRIIDSGLEXPSALQIELNLNLQQPELFKFCRENDIVVMAYTP 742
NF+ + R+++ G P+ QIEL+ L Q + FC++N IVV A++P
Sbjct: 138 NFHIPHLTRVLEEGTVVPAVNQIELHPFLSQEAIRAFCQKNGIVVEAWSP 187
>UniRef50_Q68ST9 Cluster: Reductase AKOR2; n=2; Pleurotus
djamor|Rep: Reductase AKOR2 - Pleurotus djamor
Length = 306
Score = 130 bits (313), Expect = 6e-29
Identities = 77/221 (34%), Positives = 123/221 (55%), Gaps = 13/221 (5%)
Frame = +2
Query: 125 PTLQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIED 304
P + L++G +P +ALG W G + + ++ + AL++GY HIDTA Y E
Sbjct: 5 PPIVLNTGARMPALALGGWAGLTEEERT-----QAKEWFLTALKSGYRHIDTAQIYYTEK 59
Query: 305 QVGRALTKKFSEGLKRESIFITTKL-WNSYHEREQVIPALRKSLENLNLEYVDLYLIHWP 481
VG A+ + G+ RE +FITTKL WN +H R V + +KSLENL EY+DLYL+H+P
Sbjct: 60 SVGNAIRES---GIPREELFITTKLPWN-HHSR--VAESFQKSLENLGTEYIDLYLVHFP 113
Query: 482 IAMFENDT------------LLDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRII 625
+F ++T ++++ D W + G K+IG+SN++ + ++ ++
Sbjct: 114 QRVFYDETTDFPRNPDGSIKVVNSPTLNDVWADVETLLDTGKVKAIGVSNYSIKTLEELL 173
Query: 626 DSGLEXPSALQIELNLNLQQPELFKFCRENDIVVMAYTPFG 748
+ P+ Q+EL+ L Q +L +C+E I V AYTP G
Sbjct: 174 KTAKVVPAVNQVELHPFLAQSKLLAYCKEKGIAVTAYTPTG 214
>UniRef50_Q890A0 Cluster: Oxidoreductase; n=6; Lactobacillales|Rep:
Oxidoreductase - Lactobacillus plantarum
Length = 282
Score = 129 bits (312), Expect = 8e-29
Identities = 79/206 (38%), Positives = 112/206 (54%)
Frame = +2
Query: 134 QLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQVG 313
QL++G NIP VA GTW P G+ T QAV AL AGY HIDTA Y E VG
Sbjct: 9 QLANGVNIPKVAFGTW--QIPGGEA------TYQAVRAALAAGYRHIDTALAYQNEASVG 60
Query: 314 RALTKKFSEGLKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPIAMF 493
+A+ G+ RE IF+TTKL + + +SL+NL L+YVDLYL+H P
Sbjct: 61 QAIR---DSGIPREQIFVTTKLPAETKSYQGALNDFDRSLKNLGLDYVDLYLVHAPWPWG 117
Query: 494 ENDTLLDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGLEXPSALQIELNL 673
+ + D + LD W+ M + G K+IG+SNF ++ I++ P QI+ L
Sbjct: 118 QVGRVYDEAN-LDVWQAMEAIYQSGRAKAIGVSNFAVRDLKNILNQATIPPMVNQIQYYL 176
Query: 674 NLQQPELFKFCRENDIVVMAYTPFGS 751
+P++ KF E+ ++V AY+P +
Sbjct: 177 GFTEPKITKFSEEHAMLVEAYSPLAT 202
>UniRef50_Q9HGY0 Cluster: Glycerol dehydrogenase; n=8;
Saccharomycetaceae|Rep: Glycerol dehydrogenase -
Zygosaccharomyces rouxii (Candida mogii)
Length = 310
Score = 129 bits (312), Expect = 8e-29
Identities = 86/226 (38%), Positives = 125/226 (55%), Gaps = 19/226 (8%)
Frame = +2
Query: 128 TLQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQ 307
TL+L++G IP V LGTW R K N+ +AVI AL+AGY HID A YG E +
Sbjct: 10 TLKLNTGQTIPQVGLGTW---RSK------ENEGYKAVIEALKAGYRHIDGAAVYGNEGE 60
Query: 308 VGRALTKKFSEGLKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPIA 487
VG+A+ G+ R IF+TTKLW ++ Q AL +SL+ L L+YV LYL+HWP+
Sbjct: 61 VGKAIQ---DSGVPRNEIFLTTKLWCTHQRNPQ--EALDQSLQRLGLDYVGLYLVHWPVP 115
Query: 488 M----FENDTLLD---------NVD----FLDTWRGMIDAKKLGLTKSIGISNFNQEQIQ 616
+ ++ L +VD F+ TW M + G TK+IG+SNF+ ++
Sbjct: 116 LRTENIKDGNLFQFAEKPDGSKDVDLEWNFIKTWELMQKLLESGKTKAIGVSNFSVNNLK 175
Query: 617 RIIDSGLE--XPSALQIELNLNLQQPELFKFCRENDIVVMAYTPFG 748
++ + P+ Q+E + L Q EL ++C E IV+ AY+P G
Sbjct: 176 DLLAAPTTKVTPAVNQVEFHPLLPQEELIQYCSEKGIVIEAYSPLG 221
>UniRef50_Q7PM68 Cluster: ENSANGP00000014386; n=1; Anopheles gambiae
str. PEST|Rep: ENSANGP00000014386 - Anopheles gambiae
str. PEST
Length = 310
Score = 129 bits (311), Expect = 1e-28
Identities = 70/187 (37%), Positives = 106/187 (56%), Gaps = 12/187 (6%)
Frame = +2
Query: 224 DTEQAVIYALEAGYTHIDTAYKYGIEDQVGRALTKKFSE--GLKRESIFITTKLWNSYHE 397
D ++A+ A++ GY DTA YG E VG A+ +K E L R+ FI +KL SYH
Sbjct: 31 DGKEAIRTAIDVGYRMFDTAVAYGNEAIVGEAIREKIRECNNLTRDDFFIISKLSGSYHR 90
Query: 398 REQVIPALRKSLENLNLEYVDLYLIHWPIAM------FENDTLLDNVDF----LDTWRGM 547
++ V R +L+ L ++YVDLYL+H P+A+ N T L+ +D + W G+
Sbjct: 91 QDLVEKCCRMTLDRLGMDYVDLYLMHTPVALQSEKKCARNGTKLNAIDDSIAPTEAWIGL 150
Query: 548 IDAKKLGLTKSIGISNFNQEQIQRIIDSGLEXPSALQIELNLNLQQPELFKFCRENDIVV 727
+ GL +SIG+SNFN+ QI ++ P+ QIE ++ Q + KFC++ +I+V
Sbjct: 151 EQCYQEGLCRSIGVSNFNEHQINALLSDASIVPAVNQIECSIGFNQRPMRKFCQQQNILV 210
Query: 728 MAYTPFG 748
M YTP G
Sbjct: 211 MGYTPLG 217
>UniRef50_A7PNI3 Cluster: Chromosome chr1 scaffold_22, whole genome
shotgun sequence; n=2; Vitis vinifera|Rep: Chromosome
chr1 scaffold_22, whole genome shotgun sequence - Vitis
vinifera (Grape)
Length = 360
Score = 128 bits (310), Expect = 1e-28
Identities = 79/215 (36%), Positives = 123/215 (57%), Gaps = 11/215 (5%)
Frame = +2
Query: 137 LSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQVGR 316
L++ IP + LGTW G + V +AV AL GY ID A+ YG E +VG
Sbjct: 14 LNTKAKIPAIGLGTW----QSGGDLCV-----EAVKRALSEGYRQIDCAHLYGNEVEVGE 64
Query: 317 ALTKKFSEGLKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWP-IAMF 493
AL + F+ LKRE +F+T+KL+ + + ++ ++R SL+NL + Y+DLYL+HWP I F
Sbjct: 65 ALAEAFNGSLKREDVFLTSKLYCTMNSLNKIENSVRVSLKNLGVTYLDLYLMHWPDITAF 124
Query: 494 ------ENDTLLDNVDFLD----TWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGLEX 643
+++ D+ FL+ W+ M +LGL ++IG+SNF +QI+ ++
Sbjct: 125 GDATDPPSNSGNDHRQFLNRLKKAWKAMEGLIELGLVRAIGVSNFGVQQIKELLKFAKIV 184
Query: 644 PSALQIELNLNLQQPELFKFCRENDIVVMAYTPFG 748
P+ Q++L+ +Q EL KFC+ I V A+TP G
Sbjct: 185 PAVNQVKLHPFWRQDELVKFCQSKGIHVSAHTPLG 219
>UniRef50_A2FPE2 Cluster: Oxidoreductase, aldo/keto reductase family
protein; n=3; Trichomonas vaginalis G3|Rep:
Oxidoreductase, aldo/keto reductase family protein -
Trichomonas vaginalis G3
Length = 309
Score = 128 bits (310), Expect = 1e-28
Identities = 73/213 (34%), Positives = 124/213 (58%), Gaps = 15/213 (7%)
Frame = +2
Query: 155 IPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQVGRALTKKF 334
IP + LGT+L P V + E ++GY H+D A Y ++ +G AL++ F
Sbjct: 4 IPSIGLGTFLAEDPAALKAAVHSAIE-------DSGYRHVDCAAYYKNQEIIGEALSEIF 56
Query: 335 SEG-LKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPIAM--FENDT 505
++G +KRE ++IT+K+WN+ H + ++ ++K+L+ L LEY+DL L+HW A E+D
Sbjct: 57 AKGQVKREEVWITSKVWNTKHRPDLLVKDVKKTLKELKLEYLDLVLVHWACAFQSREDDE 116
Query: 506 LL----------DNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRI-IDSGLE-XPS 649
L +N+D L+TW+ M + LGL K IG+SNF+ EQ++R+ D G++ P
Sbjct: 117 YLPRDETGKIITENIDILETWKAMEECYNLGLAKHIGVSNFSIEQLERMRYDPGVKIQPY 176
Query: 650 ALQIELNLNLQQPELFKFCRENDIVVMAYTPFG 748
Q+E ++ LQQ + + + + +++YT G
Sbjct: 177 CNQVESHMYLQQQPMLDYLTQRKMYMISYTCLG 209
>UniRef50_Q10494 Cluster: Probable oxidoreductase C26F1.07; n=2;
Schizosaccharomyces pombe|Rep: Probable oxidoreductase
C26F1.07 - Schizosaccharomyces pombe (Fission yeast)
Length = 321
Score = 128 bits (310), Expect = 1e-28
Identities = 78/215 (36%), Positives = 116/215 (53%), Gaps = 10/215 (4%)
Frame = +2
Query: 137 LSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQVGR 316
L+ G IP + LGTW N T+ AV AL+ GY HID A YG ED+VG
Sbjct: 18 LADGSKIPGLGLGTWRSE---------PNQTKNAVKTALQYGYRHIDAAAIYGNEDEVGD 68
Query: 317 ALTKKFSEGLKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPIAM-- 490
+ + G+ R+ I++T+KLW + H E V AL K+L++L L+Y+D YLIHWP++
Sbjct: 69 GIKES---GVPRKDIWVTSKLWCNAHAPEAVPKALEKTLKDLKLDYLDEYLIHWPVSFKT 125
Query: 491 ----FEND----TLLDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGLEXP 646
F D + + +TW+ M + G + IG+SNFN ++RI+ P
Sbjct: 126 GEDKFPKDKDGNLIYEKNPIEETWKAMEKLLETGKVRHIGLSNFNDTNLERILKVAKVKP 185
Query: 647 SALQIELNLNLQQPELFKFCRENDIVVMAYTPFGS 751
+ Q+EL+ L Q E + ++ I V AY+PFG+
Sbjct: 186 AVHQMELHPFLPQTEFVEKHKKLGIHVTAYSPFGN 220
>UniRef50_Q28P63 Cluster: Aldo/keto reductase; n=4;
Rhodobacteraceae|Rep: Aldo/keto reductase - Jannaschia
sp. (strain CCS1)
Length = 276
Score = 128 bits (309), Expect = 2e-28
Identities = 78/218 (35%), Positives = 114/218 (52%), Gaps = 1/218 (0%)
Frame = +2
Query: 125 PTLQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTE-QAVIYALEAGYTHIDTAYKYGIE 301
P ++ G IP V G W QV D + V A+E GY ID AY Y E
Sbjct: 5 PVIKFHDGAQIPQVGFGIW----------QVPQDIAGETVRSAIEIGYRMIDGAYLYMNE 54
Query: 302 DQVGRALTKKFSEGLKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWP 481
+G L + GL R+ +F+TTK+WN+ + ++ +SL+ + +E +DL LIHWP
Sbjct: 55 AGLGEGLR---ASGLPRDEVFVTTKVWNNEQGAAKARASVERSLKTIGVEQLDLVLIHWP 111
Query: 482 IAMFENDTLLDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGLEXPSALQI 661
+ D +L+TW+ D + GL +SIG SNFN + ++RII E P QI
Sbjct: 112 VP--SQDL------YLETWKAFQDMRDEGLMRSIGTSNFNADHLERIIAETGEAPVLNQI 163
Query: 662 ELNLNLQQPELFKFCRENDIVVMAYTPFGSLFPSKAQP 775
ELN LQQPE+ + + +V A+TP G+ +A+P
Sbjct: 164 ELNPMLQQPEMRAVHKAHGVVTQAWTPLGNARSFEAEP 201
>UniRef50_P22045 Cluster: Probable reductase; n=101; cellular
organisms|Rep: Probable reductase - Leishmania major
Length = 284
Score = 128 bits (309), Expect = 2e-28
Identities = 76/204 (37%), Positives = 109/204 (53%)
Frame = +2
Query: 137 LSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQVGR 316
LS+G +P LG W P G+V TE AV +AL AGY HIDTA Y E+ VG
Sbjct: 11 LSNGVKMPQFGLGVW--QSPAGEV------TENAVNWALCAGYRHIDTAAIYKNEESVGA 62
Query: 317 ALTKKFSEGLKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPIAMFE 496
L + G+ RE +FITTKLWN+ E + A +S + L ++Y+DLYLIHWP +
Sbjct: 63 GLR---ASGVPREDVFITTKLWNTEQGYESTLAAFEESRQKLGVDYIDLYLIHWPRG--K 117
Query: 497 NDTLLDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGLEXPSALQIELNLN 676
+ + +LD+WR K ++IG+SNF+ ++ ++ P Q+EL+
Sbjct: 118 DILSKEGKKYLDSWRAFEQLYKEKKVRAIGVSNFHIHHLEDVLAMCTVTPMVNQVELHPL 177
Query: 677 LQQPELFKFCRENDIVVMAYTPFG 748
Q +L FC I V A++P G
Sbjct: 178 NNQADLRAFCDAKQIKVEAWSPLG 201
>UniRef50_Q03PG5 Cluster: Aldo/keto reductase of diketogulonate
reductase family; n=1; Lactobacillus brevis ATCC
367|Rep: Aldo/keto reductase of diketogulonate reductase
family - Lactobacillus brevis (strain ATCC 367 / JCM
1170)
Length = 268
Score = 127 bits (306), Expect = 4e-28
Identities = 75/207 (36%), Positives = 118/207 (57%)
Frame = +2
Query: 128 TLQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQ 307
T QLS+G IP++ GT+L + D A+ AL+AGY H+D A+ YG E
Sbjct: 3 TTQLSNGVTIPMLGFGTYLID---------SKDVPAAIKTALDAGYRHLDCAHIYGNEPA 53
Query: 308 VGRALTKKFSEGLKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPIA 487
VG A+ + G+ R +FIT+K+WN+ ++ + A ++L +L L+Y+DLYLIHWP
Sbjct: 54 VGEAIK---ASGIDRSDLFITSKVWNADQGYDKTLAAFDQTLSDLQLDYLDLYLIHWP-- 108
Query: 488 MFENDTLLDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGLEXPSALQIEL 667
E+D L LDTWR + + ++IG+SNF+++Q++++ + P QIE
Sbjct: 109 -NEDDFELT----LDTWRVLETLYQQKKVRAIGVSNFSEDQLKQVFEMATVKPMINQIER 163
Query: 668 NLNLQQPELFKFCRENDIVVMAYTPFG 748
+ Q +L +F +NDIV Y+P G
Sbjct: 164 HPYKVQADLGQFDTDNDIVNEGYSPIG 190
>UniRef50_A7BA05 Cluster: Putative uncharacterized protein; n=1;
Actinomyces odontolyticus ATCC 17982|Rep: Putative
uncharacterized protein - Actinomyces odontolyticus ATCC
17982
Length = 292
Score = 127 bits (306), Expect = 4e-28
Identities = 76/208 (36%), Positives = 114/208 (54%), Gaps = 1/208 (0%)
Frame = +2
Query: 122 VPTLQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIE 301
+PT L +G IPV+ GT+ KV DT AV ALE GY HIDTA YG E
Sbjct: 16 IPTFMLPTGSPIPVLGFGTY-------KVAP--EDTYDAVSRALEVGYRHIDTAQMYGNE 66
Query: 302 DQVGRALTKKFSEGLKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWP 481
+VG AL + G+ RE +FITTK+ NS HE ++ ++R+SLE+L +YVDL L+HWP
Sbjct: 67 AEVGAALE---ASGIAREDLFITTKVDNSNHEPDRAAASIRRSLEDLRTDYVDLLLVHWP 123
Query: 482 I-AMFENDTLLDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGLEXPSALQ 658
+ ++ D L W + DA G ++IG+SN+ +E ++ + + P LQ
Sbjct: 124 LPTLYGGDVAL-------PWPALEDAFNAGGARAIGLSNYEREHVEAVREVATVAPHVLQ 176
Query: 659 IELNLNLQQPELFKFCRENDIVVMAYTP 742
+E + +L + + +V A++P
Sbjct: 177 VESHPFFPNADLRAYAQGLGMVFEAWSP 204
>UniRef50_A1D4E3 Cluster: D-xylose reductase (Xyl1), putative; n=5;
Pezizomycotina|Rep: D-xylose reductase (Xyl1), putative
- Neosartorya fischeri (strain ATCC 1020 / DSM 3700 /
NRRL 181)(Aspergillus fischerianus (strain ATCC 1020 /
DSM 3700 / NRRL 181))
Length = 321
Score = 127 bits (306), Expect = 4e-28
Identities = 78/230 (33%), Positives = 122/230 (53%), Gaps = 17/230 (7%)
Frame = +2
Query: 116 LIVPTLQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIY-ALEAGYTHIDTAYKY 292
+ P+ +L+SG ++P+V G W +V N+T IY A++AGY D A Y
Sbjct: 1 MTTPSTKLNSGYDMPLVGFGLW----------KVNNETCADQIYHAIKAGYRLFDGACDY 50
Query: 293 GIEDQVGRALTKKFSEGL-KRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYL 469
G E + G+ + + EG+ KRE +FI +KLWNS+H+ ++V P RK L + L+Y DL++
Sbjct: 51 GNEVEAGKGVARAIQEGIVKREDLFIVSKLWNSFHDGDRVEPICRKQLADWGLDYFDLFI 110
Query: 470 IHWPIAM--------------FENDTL-LDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQ 604
+H+PIA+ EN+ L N +TW M L +SIG+SNF+
Sbjct: 111 VHFPIALKYVDPAVRYPPGWLSENNKLEFSNASIQETWTAMESLVDKKLARSIGVSNFSA 170
Query: 605 EQIQRIIDSGLEXPSALQIELNLNLQQPELFKFCRENDIVVMAYTPFGSL 754
+ + ++ P+ LQIE + L Q L + ++ I V AY+ FG L
Sbjct: 171 QLLMDLLRYARIRPATLQIEHHPYLTQERLVTYAQKEGIAVTAYSSFGPL 220
>UniRef50_Q9ZBW7 Cluster: Putative oxidoreductase; n=2;
Actinomycetales|Rep: Putative oxidoreductase -
Streptomyces coelicolor
Length = 277
Score = 126 bits (305), Expect = 6e-28
Identities = 80/211 (37%), Positives = 112/211 (53%), Gaps = 1/211 (0%)
Frame = +2
Query: 122 VPTLQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQ-AVIYALEAGYTHIDTAYKYGI 298
VP + L++G +P + G W QV +D Q AV ALEAGY IDTA YG
Sbjct: 5 VPPIILNNGVEMPQLGFGVW----------QVPDDDAQTAVALALEAGYRSIDTAAIYGN 54
Query: 299 EDQVGRALTKKFSEGLKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHW 478
E+ GRA+ + GL RE +F+TTKLWNS + + A S+ L LEY+DLYLIHW
Sbjct: 55 EEGTGRAIA---ASGLAREDLFVTTKLWNSDQGYDSTLRAFDTSMAKLGLEYLDLYLIHW 111
Query: 479 PIAMFENDTLLDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGLEXPSALQ 658
P+ E ++DT++ G ++IG+SNF E ++R+ P+ Q
Sbjct: 112 PMPAKER--------YVDTYKAFEKLLADGRVRAIGVSNFLPEHLERLTAETSVIPAVNQ 163
Query: 659 IELNLNLQQPELFKFCRENDIVVMAYTPFGS 751
IEL+ +LQQ + E I A++P GS
Sbjct: 164 IELHPHLQQHAAREVHAEQGIATEAWSPLGS 194
>UniRef50_Q0CLQ2 Cluster: Putative uncharacterized protein; n=1;
Aspergillus terreus NIH2624|Rep: Putative
uncharacterized protein - Aspergillus terreus (strain
NIH 2624)
Length = 301
Score = 126 bits (305), Expect = 6e-28
Identities = 87/242 (35%), Positives = 128/242 (52%), Gaps = 34/242 (14%)
Frame = +2
Query: 128 TLQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQ 307
+ +LSSG ++P V LGTWL +P ++ E AV AL GY HID A Y E++
Sbjct: 6 SFKLSSGYDMPAVGLGTWLS-KP--------HEVENAVETALRLGYRHIDAAACYLNENE 56
Query: 308 VGRALTKKFSEGLKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYL------ 469
VG K G+ R+ IFIT+KLWN++H + V A+ K+L++L +Y+DLYL
Sbjct: 57 VGNGWKKS---GVPRDQIFITSKLWNTHHHPDHVEEAVNKTLKDLQTDYLDLYLVFPSLL 113
Query: 470 --------------IHWPIAM-FENDTL-----------LDNVDFLDTWRGMIDAKKLGL 571
IHWP+A N+TL L N+ DTW + G
Sbjct: 114 VLIHDLLSLLTNNKIHWPVAFEHTNETLTPIDPVSKRFRLANIPIADTWAALEKLVDAGK 173
Query: 572 TKSIGISNFNQEQIQRIIDSGLEXPSALQIELNLNLQQPELFKFCRE--NDIVVMAYTPF 745
+SIG+SNF E+I+ ++ + P+ QIE + LQQP L K+ +E +I+ +AY+P
Sbjct: 174 VRSIGVSNFTIEKIEELLKTARIPPAVNQIEAHPYLQQPALHKYLKEKVTNILSVAYSPL 233
Query: 746 GS 751
G+
Sbjct: 234 GN 235
>UniRef50_Q96JD6-2 Cluster: Isoform 2 of Q96JD6 ; n=4;
Catarrhini|Rep: Isoform 2 of Q96JD6 - Homo sapiens
(Human)
Length = 263
Score = 94.7 bits (225), Expect(2) = 6e-28
Identities = 52/113 (46%), Positives = 68/113 (60%), Gaps = 1/113 (0%)
Frame = +2
Query: 149 GNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQVGRALTK 328
G+IP V L +W GKV + AV A++AGY H D AY Y E +VG +
Sbjct: 2 GDIPAVGLSSWKAS--PGKVTE-------AVKEAIDAGYRHFDCAYFYHNEREVGAGIRC 52
Query: 329 KFSEG-LKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPI 484
K EG ++RE +FI TKLW + H++ V A RKSL+ L L Y+DLYLIHWP+
Sbjct: 53 KIKEGAVRREDLFIATKLWCTCHKKSLVETACRKSLKALKLNYLDLYLIHWPM 105
Score = 53.2 bits (122), Expect(2) = 6e-28
Identities = 27/65 (41%), Positives = 39/65 (60%), Gaps = 2/65 (3%)
Frame = +2
Query: 497 NDTLLDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDS-GLE-XPSALQIELN 670
N + + DFLDTW M D GL K+IG+SNFN EQ++R+++ GL P QI +
Sbjct: 139 NMVIPSDTDFLDTWEAMEDLVITGLVKNIGVSNFNHEQLERLLNKPGLRFKPLTNQILIR 198
Query: 671 LNLQQ 685
+Q+
Sbjct: 199 FQIQR 203
>UniRef50_A5PDA8 Cluster: Putative oxidoreductase protein; n=1;
Erythrobacter sp. SD-21|Rep: Putative oxidoreductase
protein - Erythrobacter sp. SD-21
Length = 272
Score = 126 bits (304), Expect = 8e-28
Identities = 78/208 (37%), Positives = 112/208 (53%)
Frame = +2
Query: 125 PTLQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIED 304
PTL L+ G IP + GTW D QAV A++ GY IDTA YG E
Sbjct: 5 PTLNLNDGRQIPQLGFGTWQMEE---------EDAPQAVSTAIDVGYWLIDTAAIYGNEK 55
Query: 305 QVGRALTKKFSEGLKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPI 484
VG+ + + +S+ IF+ TK+WN ++ + A K LE L E+VD+ LIHWP
Sbjct: 56 GVGKGVGE-WSD------IFLQTKIWNDSQGYDRTLRAAEKCLERLGREHVDMLLIHWPC 108
Query: 485 AMFENDTLLDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGLEXPSALQIE 664
E D F+DTW+ +I+ + G KSIG+SNF +E ++RIID P+ QIE
Sbjct: 109 P--EKD------QFVDTWKALIELRDAGKAKSIGVSNFREEDLKRIIDETGVTPALNQIE 160
Query: 665 LNLNLQQPELFKFCRENDIVVMAYTPFG 748
L+ + QQ ++ K + IV +++P G
Sbjct: 161 LHPSFQQRDMRKVHEDLGIVTQSWSPLG 188
>UniRef50_Q8G7K9 Cluster: Dehydrogenase or reductase protein; n=4;
Bifidobacterium|Rep: Dehydrogenase or reductase protein
- Bifidobacterium longum
Length = 289
Score = 126 bits (303), Expect = 1e-27
Identities = 77/208 (37%), Positives = 113/208 (54%), Gaps = 1/208 (0%)
Frame = +2
Query: 122 VPTLQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIE 301
VP + L G +IP V LG L +G V V + ALEAGY HID A Y E
Sbjct: 11 VPDIALKDGHSIPQVGLGV-LRIDDEGVVPVVES--------ALEAGYRHIDGAAGYNNE 61
Query: 302 DQVGRALTKK-FSEGLKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHW 478
VGRAL +++G KRE++++TTKL +S + + A SL+ L L+YVD+Y+IHW
Sbjct: 62 AGVGRALAASGYNKGAKRETLWVTTKLRDSQQGYDSALKAFDNSLKLLQLDYVDMYMIHW 121
Query: 479 PIAMFENDTLLDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGLEXPSALQ 658
P T DTW+ + + G+ +++G+ NF ++R+ + P+ Q
Sbjct: 122 PTPFDWRST--------DTWKAFVKLRDEGMARTLGVCNFMPADLKRLHEETGAWPAVNQ 173
Query: 659 IELNLNLQQPELFKFCRENDIVVMAYTP 742
IEL+ QQ E+ FC+E+ I V AY+P
Sbjct: 174 IELHPTWQQREVVAFCKEHGIAVEAYSP 201
>UniRef50_A2QVE5 Cluster: Similarity: shows similarity to several
dehydrogenases of different specificities; n=4;
Pezizomycotina|Rep: Similarity: shows similarity to
several dehydrogenases of different specificities -
Aspergillus niger
Length = 381
Score = 126 bits (303), Expect = 1e-27
Identities = 78/223 (34%), Positives = 117/223 (52%), Gaps = 18/223 (8%)
Frame = +2
Query: 137 LSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQVGR 316
L+SG IP + GTW G+V AV AL+AGY H+D A Y + +V
Sbjct: 9 LNSGAQIPQLGFGTW--QSAPGQV-------GDAVYEALKAGYRHLDLATIYQNQREVAE 59
Query: 317 ALTKKFSE--GLKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPIAM 490
+ + + + GLKRE IFIT+KLWNS H+ V AL + L L L+Y+DLYL+HWP++
Sbjct: 60 GIKRAYKDVPGLKREDIFITSKLWNSQHDPAVVEKALDECLAELELDYLDLYLVHWPVSF 119
Query: 491 FENDTLL----------------DNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRI 622
L D++ +DTW+ M K +++G+SN ++ I
Sbjct: 120 TTGSELFPLVKDSSVEGGDVVINDDISIVDTWKAMTQLPK-SKARTVGVSNHMIPHLEAI 178
Query: 623 IDSGLEXPSALQIELNLNLQQPELFKFCRENDIVVMAYTPFGS 751
I++ P+ QIE + LQ EL ++C++ I V AY+ FG+
Sbjct: 179 INATGVVPAVNQIERHPVLQSNELIEYCQKKGIHVTAYSAFGN 221
>UniRef50_Q2V420 Cluster: Uncharacterized protein At2g37770.1; n=1;
Arabidopsis thaliana|Rep: Uncharacterized protein
At2g37770.1 - Arabidopsis thaliana (Mouse-ear cress)
Length = 283
Score = 125 bits (301), Expect = 2e-27
Identities = 73/203 (35%), Positives = 114/203 (56%), Gaps = 7/203 (3%)
Frame = +2
Query: 134 QLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQVG 313
+L++G P V LGTW G V AV A++ GY HID A YG E ++G
Sbjct: 9 KLNTGAKFPSVGLGTW--QASPGLV-------GDAVAAAVKIGYRHIDCAQIYGNEKEIG 59
Query: 314 RALTKKFSEGL-KRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPIAM 490
L K F + + KRE +FIT+KLW + H+ + V AL ++L++L LEYVDLYLIHWP +
Sbjct: 60 AVLKKLFEDRVVKREDLFITSKLWCTDHDPQDVPEALNRTLKDLQLEYVDLYLIHWPARI 119
Query: 491 ------FENDTLLDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGLEXPSA 652
+ + LL VD TW+ M G ++IG+SNF+ +++ +++ P+
Sbjct: 120 KKGSVGIKPENLLP-VDIPSTWKAMEALYDSGKARAIGVSNFSTKKLADLLELARVPPAV 178
Query: 653 LQIELNLNLQQPELFKFCRENDI 721
Q+E + + +Q +L +FC+ +
Sbjct: 179 NQVECHPSWRQTKLQEFCKSKGV 201
>UniRef50_A3LTU8 Cluster: D-arabinose dehydrogenase; n=5;
Saccharomycetales|Rep: D-arabinose dehydrogenase -
Pichia stipitis (Yeast)
Length = 326
Score = 125 bits (301), Expect = 2e-27
Identities = 79/226 (34%), Positives = 126/226 (55%), Gaps = 21/226 (9%)
Frame = +2
Query: 137 LSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQVGR 316
LS+G IP + LGT P ++ ++ VI A++AGY HIDTA+ YG E+ +G+
Sbjct: 12 LSNGKTIPALGLGTVPPEDP--------HELKEQVITAVKAGYRHIDTAWYYGTEEYIGQ 63
Query: 317 ALTKKFSEGL-KRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPIAMF 493
AL + F EG+ KRE +FITTK+W S+ + +L KSL +L L+YVDL+L HWP+ +
Sbjct: 64 ALKQLFEEGIVKREDLFITTKVWPSFWRNPE--KSLDKSLADLGLDYVDLFLQHWPVVLH 121
Query: 494 --EN----------------DTLLDNVDFLDTWRGMID-AKKLGLTKSIGISNFNQEQIQ 616
EN D + + ++D + + D KSIG+SN++ +++
Sbjct: 122 GDENGLPPQPRDKDGKLIYDDDPVSGIKYIDAYHSLEDIMDNTSKVKSIGVSNYSIPKLR 181
Query: 617 RIIDS-GLEXPSALQIELNLNLQQPELFKFCRENDIVVMAYTPFGS 751
+++ + P QIE + L Q +L K+C +N + + AY+P GS
Sbjct: 182 KLLAAVRKHKPVVNQIEYHPLLPQQDLVKYCYDNGVHISAYSPVGS 227
>UniRef50_Q1VRG6 Cluster: YvgN; n=1; Psychroflexus torquis ATCC
700755|Rep: YvgN - Psychroflexus torquis ATCC 700755
Length = 280
Score = 124 bits (299), Expect = 3e-27
Identities = 76/204 (37%), Positives = 111/204 (54%), Gaps = 2/204 (0%)
Frame = +2
Query: 137 LSSGGNIPVVALGTWLGHRPKG-KVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQVG 313
L+ G IP+V GT+ + +G K +Q + AL GY IDT Y E+ VG
Sbjct: 5 LNDGNRIPIVGFGTYKANEEEGIKSIQKS---------ALTLGYRLIDTVAIYQNEEAVG 55
Query: 314 RALTKKFSEGLKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPI-AM 490
+A+ + G+ RE IF+TTKLW +Q AL +SL L+L Y+DLYLIHWP A+
Sbjct: 56 KAIKAR---GVLREEIFVTTKLWRENLGYKQTRIALDESLRKLDLNYIDLYLIHWPANAI 112
Query: 491 FENDTLLDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGLEXPSALQIELN 670
D N DTWR M + + G KS+G+SNF E ++ + + PS QIE +
Sbjct: 113 NYKDWQKTNA---DTWRAMEELQAEGKIKSLGVSNFWPEHLEALFQTAKVSPSVNQIEFH 169
Query: 671 LNLQQPELFKFCRENDIVVMAYTP 742
QP++ +FC+ + I V +++P
Sbjct: 170 PGYWQPQVTEFCKNHGIAVESWSP 193
>UniRef50_A4RQH8 Cluster: Predicted protein; n=2; Ostreococcus|Rep:
Predicted protein - Ostreococcus lucimarinus CCE9901
Length = 337
Score = 124 bits (299), Expect = 3e-27
Identities = 78/217 (35%), Positives = 109/217 (50%), Gaps = 8/217 (3%)
Frame = +2
Query: 140 SSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQVGRA 319
++G IP V LGTW RP N+ AV AL AGY H+D A Y E +VG A
Sbjct: 11 ANGLRIPRVGLGTWKA-RP--------NEVRDAVRDALGAGYAHVDCAAAYANESEVGEA 61
Query: 320 LTKKFSEG-LKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPIAMFE 496
L + F G KRE +F+T+KLWN V AL +L +L + Y+DLYLIHWP+A
Sbjct: 62 LREAFERGDAKREDVFVTSKLWNDRRRPRDVREALMTTLNDLGVGYLDLYLIHWPVAWKR 121
Query: 497 NDTLLDNVD--FLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGLE--XPSALQIE 664
L + + + W + GL + IG+SNFN+ Q+ + D P+ QIE
Sbjct: 122 GTVLQPDAEASIAECWSELERCVADGLVRHIGVSNFNEAQLAALCDDPRTKIQPACNQIE 181
Query: 665 LNLNLQQPELFKFCRENDIVVMAYTPF---GSLFPSK 766
+ L K+ + + V AY+P G LF ++
Sbjct: 182 SHPLWSNDSLVKYSQSKGLTVTAYSPLAQGGELFENE 218
>UniRef50_Q568D7 Cluster: Zgc:110366; n=7; Euteleostomi|Rep:
Zgc:110366 - Danio rerio (Zebrafish) (Brachydanio rerio)
Length = 289
Score = 124 bits (298), Expect = 4e-27
Identities = 75/210 (35%), Positives = 115/210 (54%), Gaps = 1/210 (0%)
Frame = +2
Query: 116 LIVPTLQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYAL-EAGYTHIDTAYKY 292
L P + L +G NIP++ LGT H + +AV+YAL E G HIDTA +Y
Sbjct: 11 LSCPAVPLHNGLNIPILGLGT--SH--------YGGYSHEAVLYALQECGIRHIDTAKRY 60
Query: 293 GIEDQVGRALTKKFSEGLKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLI 472
G E+ +G+A+T+ G++RE +++TTKLW + + A R S L ++Y+DLYL+
Sbjct: 61 GCEEALGKAVTES---GVQREELWVTTKLWPGDYGYQSTKQACRDSRARLGVDYLDLYLM 117
Query: 473 HWPIAMFENDTLLDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGLEXPSA 652
HWP +M + L+TWR + + GL ++IG+SNF + + DSG P
Sbjct: 118 HWPDSMVPGRS--SQEVRLETWRALEELYDEGLCRAIGVSNFLIPHLNELKDSGGIVPHV 175
Query: 653 LQIELNLNLQQPELFKFCRENDIVVMAYTP 742
Q+E + Q +L + CR+ +IV Y P
Sbjct: 176 NQVEFHPFQQPMKLVEHCRKENIVFEGYCP 205
>UniRef50_Q7N0E4 Cluster: 2,5-diketo-D-gluconic acid reductase A;
n=2; Bacteria|Rep: 2,5-diketo-D-gluconic acid reductase
A - Photorhabdus luminescens subsp. laumondii
Length = 292
Score = 123 bits (297), Expect = 5e-27
Identities = 80/206 (38%), Positives = 114/206 (55%)
Frame = +2
Query: 125 PTLQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIED 304
P ++L+ G ++P + LG+W Q +T A AL+ GY IDTA Y E
Sbjct: 5 PIIRLADGNHMPQLGLGSWASDD------QQIAETIHA---ALDIGYRAIDTAAIYNNEK 55
Query: 305 QVGRALTKKFSEGLKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPI 484
VG AL + + RE IF+TTKLWN H + AL +SLE L L+YVDLYLIHWP
Sbjct: 56 GVGNALQET---DIPREDIFVTTKLWNDRHLDARA--ALTESLEKLQLDYVDLYLIHWPA 110
Query: 485 AMFENDTLLDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGLEXPSALQIE 664
+ ++ W+ +I+ +K GL +SIG+SNF E IQR+I+ P QIE
Sbjct: 111 PPQDQ--------YVGAWQQLIELQKEGLIRSIGVSNFQPEHIQRLINETGVHPVINQIE 162
Query: 665 LNLNLQQPELFKFCRENDIVVMAYTP 742
L+ LQQ +L + ++IV +++P
Sbjct: 163 LHPLLQQRQLHAWNATHNIVTESWSP 188
>UniRef50_Q24C22 Cluster: Oxidoreductase, aldo/keto reductase family
protein; n=4; Oligohymenophorea|Rep: Oxidoreductase,
aldo/keto reductase family protein - Tetrahymena
thermophila SB210
Length = 297
Score = 123 bits (297), Expect = 5e-27
Identities = 74/209 (35%), Positives = 113/209 (54%), Gaps = 2/209 (0%)
Frame = +2
Query: 122 VPTLQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIE 301
VP L GG+IP + GT+ ++ Q ND V AL+ GYTHIDTA Y E
Sbjct: 13 VPILNFREGGSIPQIGYGTY-------ELRQ--NDCIIGVTEALKIGYTHIDTASVYRNE 63
Query: 302 DQVGRALTKKFSEGLKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWP 481
+ + + + G+KRE +FIT+K+ EQ A++ L LN++Y+D LIHWP
Sbjct: 64 QDIAKVIHNP-AYGIKREDLFITSKISPGEQGYEQAKKAVQDMLTRLNIKYLDCVLIHWP 122
Query: 482 --IAMFENDTLLDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGLEXPSAL 655
+ ND + L+TW+ +I+ +K G+ K IG+SNFN +Q +I+ P
Sbjct: 123 GVSKLPPNDPKNAQIR-LETWKALIELRKAGVIKHIGVSNFNINHLQHLIEKSEFKPEMN 181
Query: 656 QIELNLNLQQPELFKFCRENDIVVMAYTP 742
Q E++ + +FC++N I+V AY+P
Sbjct: 182 QFEIHPLCFNKKTIEFCQKNGILVEAYSP 210
>UniRef50_P38715 Cluster: NADPH-dependent aldose reductase GRE3;
n=39; cellular organisms|Rep: NADPH-dependent aldose
reductase GRE3 - Saccharomyces cerevisiae (Baker's
yeast)
Length = 327
Score = 123 bits (297), Expect = 5e-27
Identities = 92/262 (35%), Positives = 133/262 (50%), Gaps = 28/262 (10%)
Frame = +2
Query: 137 LSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQVGR 316
L++G +P+V LG W + KV + A++ GY D A YG E +VG
Sbjct: 7 LNNGLKMPLVGLGCW---KIDKKVCA------NQIYEAIKLGYRLFDGACDYGNEKEVGE 57
Query: 317 ALTKKFSEGL-KRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPIAM- 490
+ K SEGL R+ IF+ +KLWN++H + V AL+K+L ++ L+Y+DLY IH+PIA
Sbjct: 58 GIRKAISEGLVSRKDIFVVSKLWNNFHHPDHVKLALKKTLSDMGLDYLDLYYIHFPIAFK 117
Query: 491 ---FEND------TLLD----------NVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQI 613
FE T D +V +DT+R + + GL KSIG+SNF I
Sbjct: 118 YVPFEEKYPPGFYTGADDEKKGHITEAHVPIIDTYRALEECVDEGLIKSIGVSNFQGSLI 177
Query: 614 QRIIDSGLEXPSALQIELNLNLQQPELFKFCRENDIVVMAYTPFG-------SLFPSKAQ 772
Q ++ P ALQIE + L Q L +FC+ +DI V+AY+ FG L +K
Sbjct: 178 QDLLRGCRIKPVALQIEHHPYLTQEHLVEFCKLHDIQVVAYSSFGPQSFIEMDLQLAKTT 237
Query: 773 PDAPRRGLTMNVSSVSPXNTTN 838
P + VS P +TT+
Sbjct: 238 PTLFENDVIKKVSQNHPGSTTS 259
>UniRef50_UPI0000DB6EE9 Cluster: PREDICTED: similar to C35D10.6;
n=2; Endopterygota|Rep: PREDICTED: similar to C35D10.6 -
Apis mellifera
Length = 292
Score = 123 bits (296), Expect = 7e-27
Identities = 76/215 (35%), Positives = 118/215 (54%), Gaps = 4/215 (1%)
Frame = +2
Query: 119 IVPTLQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGI 298
IV + LSSG ++P++ GT+ +Q Q V +L G+ IDTA Y
Sbjct: 4 IVRNVCLSSGYDMPLIGFGTYK--------IQGRELVYQVVDESLNVGFRSIDTAVGYRN 55
Query: 299 EDQVGRALTKKFSE-GLKRESIFITTKLWNSYH-EREQVIPALRKSLENLNLEYVDLYLI 472
E+ +G AL + L+R IFITTKL S + + + + ++KSL+ N Y+DLYLI
Sbjct: 56 EEDIGYALKNLLPKYNLQRSDIFITTKLPPSVNGDPKGIEQCVQKSLKAFNTTYIDLYLI 115
Query: 473 HWPIAMFENDTLLDNVDF-LDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGLE-XP 646
HWP A +T +N TW ++D KK G +SIG+SNF + +Q ++ + + P
Sbjct: 116 HWPGATRIPETSTNNPSLRAKTWNKLVDLKKQGFIRSIGVSNFTIKHLQELLQNCKDILP 175
Query: 647 SALQIELNLNLQQPELFKFCRENDIVVMAYTPFGS 751
+ Q+EL+ + +Q EL K+C E I + AY+ G+
Sbjct: 176 AVNQVELHPHYRQEELIKYCNEKGIHIQAYSSLGT 210
>UniRef50_Q5HR31 Cluster: Oxidoreductase, aldo/keto reductase
family; n=3; Staphylococcus|Rep: Oxidoreductase,
aldo/keto reductase family - Staphylococcus epidermidis
(strain ATCC 35984 / RP62A)
Length = 279
Score = 122 bits (295), Expect = 9e-27
Identities = 75/202 (37%), Positives = 113/202 (55%)
Frame = +2
Query: 137 LSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQVGR 316
L++G +P V LG + K+ E+ V AL+AGY DTAY YG E +G
Sbjct: 8 LNNGYPMPAVGLGVY-------KIAD--EQMEEVVRTALDAGYRAFDTAYFYGNEKALGS 58
Query: 317 ALTKKFSEGLKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPIAMFE 496
AL K S ++R+ +FIT+KLWN Y +Q I KSL+NL L+Y+DL+LIHWP E
Sbjct: 59 AL--KHSN-VERDELFITSKLWNDYQGYDQTIEYFNKSLDNLGLDYLDLFLIHWPC---E 112
Query: 497 NDTLLDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGLEXPSALQIELNLN 676
ND L ++++++ + + G K+IG+ NF +++++ P QIEL+
Sbjct: 113 NDQL-----YIESYKALEHLYEEGKIKAIGVCNFKIHHLEKLMKETKITPQVNQIELHPY 167
Query: 677 LQQPELFKFCRENDIVVMAYTP 742
Q ++ FC E+DI V A+ P
Sbjct: 168 FNQQDVQDFCDEHDIKVTAWMP 189
>UniRef50_Q1IN88 Cluster: Aldehyde reductase; n=5; Bacteria|Rep:
Aldehyde reductase - Acidobacteria bacterium (strain
Ellin345)
Length = 313
Score = 122 bits (295), Expect = 9e-27
Identities = 72/212 (33%), Positives = 115/212 (54%), Gaps = 12/212 (5%)
Frame = +2
Query: 149 GNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQVGRALTK 328
G+IP + GT + + T D AL AG+ H D A +Y E +VG AL
Sbjct: 18 GHIPALGFGTLIAD--PALTITATRD-------ALAAGFRHFDCAERYRNEREVGEALRA 68
Query: 329 KFSEG-LKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPIAM----- 490
+ G + RE IF+TTKLWN+ H E+V PA SL+ L L+Y+DLYLIH P A
Sbjct: 69 GRAAGNIAREEIFVTTKLWNTNHRPERVEPAFEASLDRLGLDYLDLYLIHTPFAFQPGDE 128
Query: 491 ----FENDTLL--DNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGLEXPSA 652
+N +++ + V +TW + + G ++IG+S+ + +++ I ++ P+
Sbjct: 129 QDPRDQNGSVIYDEGVTLRETWSALENLVDRGRCRAIGLSDISMDRLAPIYEAARIKPAV 188
Query: 653 LQIELNLNLQQPELFKFCRENDIVVMAYTPFG 748
+Q+E + L + EL +FC+ N IV++A+ P G
Sbjct: 189 VQVESHPYLPETELLEFCKRNGIVLLAFAPLG 220
>UniRef50_A6ESC0 Cluster: ARA1; n=1; unidentified eubacterium
SCB49|Rep: ARA1 - unidentified eubacterium SCB49
Length = 280
Score = 122 bits (295), Expect = 9e-27
Identities = 70/207 (33%), Positives = 108/207 (52%), Gaps = 2/207 (0%)
Frame = +2
Query: 134 QLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQVG 313
+L++ NIP + GTW P G+ A+ A++AGY HID A Y E VG
Sbjct: 6 KLNNNINIPAIGFGTW--QTPDGQTAI------NAIKTAIDAGYKHIDAAAIYKNEKGVG 57
Query: 314 RALTKKFSEGLKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPIA-- 487
+ + + R+ +F+T+K+WN E + A ++ +L L+Y+DLYLIHWP A
Sbjct: 58 LGIKEA---NIDRKDLFVTSKVWNEQRGYENTLKAFDNTINDLQLDYLDLYLIHWPAAAH 114
Query: 488 MFENDTLLDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGLEXPSALQIEL 667
FEN L+N DTW M K G K++G+SNF + + ++ P+ QIE
Sbjct: 115 QFENWKQLNN----DTWSAMEKLYKDGKIKALGVSNFMEHHLTPLLQHATIKPTVNQIEY 170
Query: 668 NLNLQQPELFKFCRENDIVVMAYTPFG 748
+ Q + +FC +N+I V ++P G
Sbjct: 171 HPGYMQQDCVQFCNDNNIQVEGWSPLG 197
>UniRef50_Q4Q5N9 Cluster: Prostaglandin f synthase, putative; n=7;
cellular organisms|Rep: Prostaglandin f synthase,
putative - Leishmania major
Length = 279
Score = 122 bits (295), Expect = 9e-27
Identities = 69/204 (33%), Positives = 109/204 (53%)
Frame = +2
Query: 137 LSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQVGR 316
LS+G +P + +GTW + +VV + +A+ AGY H+DTA+ Y E VG+
Sbjct: 10 LSNGVQVPQLGIGTWEA-KDGNEVVNIK--------WAVNAGYRHVDTAHYYKNEKGVGQ 60
Query: 317 ALTKKFSEGLKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPIAMFE 496
+++ G+ R IF+TTKLWN H E + A +S + L +EYVDLYLIHWP
Sbjct: 61 GISEC---GVPRSDIFVTTKLWNYDHGYESALAAFEQSRQALGVEYVDLYLIHWP----- 112
Query: 497 NDTLLDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGLEXPSALQIELNLN 676
N +++TWR ++ ++IG+SNF + ++ + P Q+E++ +
Sbjct: 113 ----GPNRSYIETWRAFEKLYEMKKVRAIGVSNFEPHHLDDLLANCTVPPMVNQVEMHPH 168
Query: 677 LQQPELFKFCRENDIVVMAYTPFG 748
QQ L +C E +I V A+ P G
Sbjct: 169 FQQKALRAYCAEKNIAVTAWRPLG 192
>UniRef50_Q6C2L0 Cluster: Yarrowia lipolytica chromosome F of strain
CLIB122 of Yarrowia lipolytica; n=3; Yarrowia
lipolytica|Rep: Yarrowia lipolytica chromosome F of
strain CLIB122 of Yarrowia lipolytica - Yarrowia
lipolytica (Candida lipolytica)
Length = 324
Score = 122 bits (295), Expect = 9e-27
Identities = 80/228 (35%), Positives = 128/228 (56%), Gaps = 17/228 (7%)
Frame = +2
Query: 119 IVPTLQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGI 298
I + +L+ G +IP + LGT G V E+ V A++ GY HIDTA+ YG
Sbjct: 3 ITDSFKLNDGHSIPALGLGT----ASDGNV-------EEVVYAAIKNGYRHIDTAFIYGS 51
Query: 299 EDQVGRALTKKFSEGL-KRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIH 475
E VG+ + + E L KRE++F+TTK+W +++ R V +L SL++L+L+YVDL L+H
Sbjct: 52 EVDVGKGIKRAIDEELVKRENLFVTTKVWPTFYNR--VSESLDISLKDLSLDYVDLLLVH 109
Query: 476 WPIAMF------------ENDTLLDNVDFLDTW---RGMIDAKKL-GLTKSIGISNFNQE 607
WP+++ D + D LD W I+ +KL G TKSIG+SN ++
Sbjct: 110 WPVSLLADSDDPRAIYLVNTDGSVRYSDSLDDWITTYKQIEEEKLSGRTKSIGVSNVSEV 169
Query: 608 QIQRIIDSGLEXPSALQIELNLNLQQPELFKFCRENDIVVMAYTPFGS 751
++R++D P+ Q E++ L Q + +F ++ I+V A++P GS
Sbjct: 170 YLKRLLDQVKTVPAVNQFEIHPYLPQKKEIEFNEKHGILVTAFSPLGS 217
>UniRef50_Q8ZI40 Cluster: 2,5-diketo-D-gluconic acid reductase A;
n=74; Bacteria|Rep: 2,5-diketo-D-gluconic acid reductase
A - Yersinia pestis
Length = 277
Score = 122 bits (295), Expect = 9e-27
Identities = 79/206 (38%), Positives = 111/206 (53%)
Frame = +2
Query: 125 PTLQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIED 304
P ++L G +P + LG W +TE AV ALE GY IDTA Y E+
Sbjct: 5 PLIKLYDGRLMPQLGLGVWQAS---------IQETELAVSKALEVGYRSIDTAAIYKNEE 55
Query: 305 QVGRALTKKFSEGLKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPI 484
VG+AL + + R+ +FITTKLWN Q AL SL+ L L+YVDLYLIHWP
Sbjct: 56 GVGKALK---AAAVARDELFITTKLWNDDQHNPQ--QALETSLQKLQLDYVDLYLIHWP- 109
Query: 485 AMFENDTLLDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGLEXPSALQIE 664
D D+ ++ WR ++ K+ GL +SIG+ NF+ +QR+ID P+ QIE
Sbjct: 110 -----DPKQDH--YVSAWRELVTLKEQGLIRSIGVCNFHIPHLQRLIDETGIAPTVNQIE 162
Query: 665 LNLNLQQPELFKFCRENDIVVMAYTP 742
L+ LQQ +L + + I +++P
Sbjct: 163 LHPLLQQRQLHAWNATHHIATESWSP 188
>UniRef50_UPI0000499B0E Cluster: oxidoreductase, aldo/keto reductase
family; n=1; Entamoeba histolytica HM-1:IMSS|Rep:
oxidoreductase, aldo/keto reductase family - Entamoeba
histolytica HM-1:IMSS
Length = 307
Score = 121 bits (292), Expect = 2e-26
Identities = 77/211 (36%), Positives = 114/211 (54%), Gaps = 7/211 (3%)
Frame = +2
Query: 137 LSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQVGR 316
L++G +P + LGTWL + +AV ALE GY ID A Y E ++G
Sbjct: 8 LNNGKFMPAIGLGTWLA---------APGEVGKAVTLALENGYRLIDCARFYKNEKEIGE 58
Query: 317 ALTKKFSEGLKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPIAMFE 496
+ F + RE +F+T+KLW R + + +S+++L +Y+DLYLIHWPIA+
Sbjct: 59 MGIEPFLKNHPREELFVTSKLWMDQVTR--IRESCLESIQDLKCKYLDLYLIHWPIALKV 116
Query: 497 N-------DTLLDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGLEXPSAL 655
+ + LD +D + W+ M GL KSIG+SNF QI++I+ P
Sbjct: 117 DASNPPKPEDFLD-MDITEIWQEMERLVDEGLVKSIGLSNFTIPQIEKIMKMCRIKPVIN 175
Query: 656 QIELNLNLQQPELFKFCRENDIVVMAYTPFG 748
Q+ELN+ LQQ +L + C+ +IVV AY P G
Sbjct: 176 QVELNVYLQQNKLREVCKSYNIVVEAYRPIG 206
>UniRef50_Q235V6 Cluster: Oxidoreductase, aldo/keto reductase family
protein; n=2; Tetrahymena thermophila SB210|Rep:
Oxidoreductase, aldo/keto reductase family protein -
Tetrahymena thermophila SB210
Length = 332
Score = 121 bits (291), Expect = 3e-26
Identities = 71/215 (33%), Positives = 120/215 (55%), Gaps = 1/215 (0%)
Frame = +2
Query: 134 QLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQVG 313
+L++G +P+V LGT+L + + ++TN + AL+AGY HIDTA Y E +G
Sbjct: 9 KLNNGQIMPLVGLGTYLLNSKE----EMTN----LLRTALDAGYRHIDTAVNYQNEAMIG 60
Query: 314 RALTKKFSEG-LKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPIAM 490
+L F EG R+ +FI +K++ + + ++ +++KSL+ L L+YVDLY +H+P+
Sbjct: 61 ESLKTIFKEGKYSRKDLFIVSKVFPN--KGINMLESVKKSLKELQLDYVDLYYLHFPLGF 118
Query: 491 FENDTLLDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGLEXPSALQIELN 670
++ W + +A +LGL KSIG+SNFN + ++ P + Q+E++
Sbjct: 119 LSEKEEFVHLPVHVAWAQLEEAHRLGLAKSIGVSNFNVMALADLLSYAKVKPVSNQVEVS 178
Query: 671 LNLQQPELFKFCRENDIVVMAYTPFGSLFPSKAQP 775
+ +QQ L KFC+ I V AY P ++ P
Sbjct: 179 VFIQQKNLIKFCQRFGIHVTAYAPLAKYTDVESNP 213
>UniRef50_UPI0000D9A956 Cluster: PREDICTED: similar to aldo-keto
reductase family 1, member B10, partial; n=1; Macaca
mulatta|Rep: PREDICTED: similar to aldo-keto reductase
family 1, member B10, partial - Macaca mulatta
Length = 275
Score = 120 bits (289), Expect = 5e-26
Identities = 73/194 (37%), Positives = 109/194 (56%), Gaps = 9/194 (4%)
Frame = +2
Query: 230 EQAVIYALEAGYTHIDTAYKYGIEDQVGRALTKKFSE-GLKRESIFITTK------LWNS 388
++AV A++AGY HID AY Y E +VG A+ +K E +KRE +FI +K LW +
Sbjct: 49 KEAVKVAIDAGYRHIDCAYVYQNEHEVGEAIQEKIQEQAVKREDLFIVSKVHMAHWLWTT 108
Query: 389 YHEREQVIPALRKSLENLNLEYVDLYLIHWPIAMFENDTLLDNVDFLDTWRGMIDAKKLG 568
+ ER V A K+L++L L Y+D+YLIHWP + L+D G
Sbjct: 109 FFERPLVRKAFEKTLKDLKLSYLDVYLIHWPQGFKAMEELVDE----------------G 152
Query: 569 LTKSIGISNFNQEQIQRIIDS-GLE-XPSALQIELNLNLQQPELFKFCRENDIVVMAYTP 742
L K++GISNFN QI+++++ GL+ P Q+E + L Q +L ++C I + AY+P
Sbjct: 153 LVKALGISNFNHFQIEKLLNKPGLKYKPVTNQVECHPYLTQEKLIQYCHSKGITITAYSP 212
Query: 743 FGSLFPSKAQPDAP 784
GS A+P+ P
Sbjct: 213 LGSPDRPWAKPEDP 226
>UniRef50_Q8F1G4 Cluster: Aldehyde reductase; n=8; Bacteria|Rep:
Aldehyde reductase - Leptospira interrogans
Length = 278
Score = 120 bits (289), Expect = 5e-26
Identities = 70/205 (34%), Positives = 116/205 (56%)
Frame = +2
Query: 128 TLQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQ 307
T+ L++G ++P++ LG W GK + ++AV+ ALEAGY HIDTA Y E
Sbjct: 11 TIMLNNGISMPILGLGVW--KTKSGK------ECKEAVLNALEAGYRHIDTARIYDNEVD 62
Query: 308 VGRALTKKFSEGLKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPIA 487
VG+A+ + G+ R+ IFITTKLWN+ ++ AL SL+ L +++VDLYLIH+P+
Sbjct: 63 VGQAIRES---GIPRKEIFITTKLWNADQGSDKTRKALENSLDRLGIDFVDLYLIHFPVT 119
Query: 488 MFENDTLLDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGLEXPSALQIEL 667
+D+W+ + L K+IG+SN+ + ++ + P+ Q+E
Sbjct: 120 SKR----------MDSWKELEKLYHDKLCKAIGVSNYTIIHLTELLKNSQITPAVNQVEF 169
Query: 668 NLNLQQPELFKFCRENDIVVMAYTP 742
+ L Q L ++C+++ I + AY+P
Sbjct: 170 HPFLNQIHLLEYCKKHKIQLEAYSP 194
>UniRef50_Q5FKI1 Cluster: Reductase-dehydrogenase; n=1;
Lactobacillus acidophilus|Rep: Reductase-dehydrogenase -
Lactobacillus acidophilus
Length = 271
Score = 120 bits (289), Expect = 5e-26
Identities = 73/205 (35%), Positives = 110/205 (53%), Gaps = 3/205 (1%)
Frame = +2
Query: 137 LSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVI-YALEAGYTHIDTAYKYGIEDQVG 313
L++G IP + LGTWL + ND V+ A+ GY DTA YG E VG
Sbjct: 9 LNNGEKIPQIQLGTWL----------INNDEVNKVVRQAVNIGYRGFDTAKDYGNESGVG 58
Query: 314 RALTKKFSEGLKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPIAMF 493
+ + ++ ++R IF+TTKL + + E A+ +L+ LEY+DL LIH P
Sbjct: 59 KGI---WNSDIERSDIFLTTKLPTAVKDYEGTKKAIDAALDKFGLEYIDLLLIHSPQPWI 115
Query: 494 ENDTLLDN--VDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGLEXPSALQIEL 667
E + D L+ WR M +A K G +SIG+SNF QE I+ I+++G P+ QIE+
Sbjct: 116 EVNRTNDRHFKGNLENWRAMEEAVKAGKVRSIGVSNFLQEDIENIVNNGTITPAVNQIEV 175
Query: 668 NLNLQQPELFKFCRENDIVVMAYTP 742
++ EL +C++ I + AY+P
Sbjct: 176 HIGKVPVELMDYCKKLGIKIEAYSP 200
>UniRef50_A6W8E7 Cluster: 2,5-didehydrogluconate reductase; n=3;
Actinomycetales|Rep: 2,5-didehydrogluconate reductase -
Kineococcus radiotolerans SRS30216
Length = 289
Score = 120 bits (289), Expect = 5e-26
Identities = 76/210 (36%), Positives = 113/210 (53%), Gaps = 1/210 (0%)
Frame = +2
Query: 116 LIVPTLQLSSGGNIPVVALGTWLGHRPKGKVVQVT-NDTEQAVIYALEAGYTHIDTAYKY 292
+ VPT+ L+ G IP + G V Q+ DT QAV AL+ GY HIDTA Y
Sbjct: 10 MTVPTILLNDGREIPQLGFG----------VFQIEPGDTAQAVKTALDLGYRHIDTAQMY 59
Query: 293 GIEDQVGRALTKKFSEGLKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLI 472
G E +V + + G+ R+ I++T+KL N +HE + A+ S+E L +DLYLI
Sbjct: 60 GNEAEVAQGIA---DSGVPRDEIWVTSKLNNGFHEPDAARKAVDDSVEKLRGP-IDLYLI 115
Query: 473 HWPIAMFENDTLLDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGLEXPSA 652
HWP+ TL DF+ TW+ + +A+ G +SIG+SNF +QR+ P+
Sbjct: 116 HWPLP-----TLYGG-DFVSTWKVLEEARAAGKLRSIGVSNFQVNHLQRLAQEATVVPAV 169
Query: 653 LQIELNLNLQQPELFKFCRENDIVVMAYTP 742
QIE++ E+ + C E+ I V A++P
Sbjct: 170 NQIEVHPYFGNEEVRRHCGEHQIGVEAWSP 199
>UniRef50_UPI00006CD296 Cluster: oxidoreductase, aldo/keto reductase
family protein; n=1; Tetrahymena thermophila SB210|Rep:
oxidoreductase, aldo/keto reductase family protein -
Tetrahymena thermophila SB210
Length = 295
Score = 120 bits (288), Expect = 7e-26
Identities = 73/206 (35%), Positives = 113/206 (54%), Gaps = 1/206 (0%)
Frame = +2
Query: 128 TLQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQ 307
T +L +G +PV LGT+ KVV + + AL+ GY HIDTA Y E Q
Sbjct: 7 TTELCNGSKLPVFGLGTY-------KVVS-KEEMVTFLRTALDLGYRHIDTAIMYENEKQ 58
Query: 308 VGRALTKKFSEG-LKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPI 484
+G AL + + EG KRE +F+ TKL+++ + +V +R+SL+NL Y+DLYL+H+
Sbjct: 59 IGDALQEIYKEGKYKREDLFLVTKLFSN--KNTKVEDQVRQSLQNLQTNYIDLYLLHYAS 116
Query: 485 AMFENDTLLDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGLEXPSALQIE 664
+ + L + W + + GL ++IGISNFN + + + P QIE
Sbjct: 117 SPPTDQFELTHKPVFQVWAEFEELVQKGLIRNIGISNFNVQMLLDLYSYCKIKPVVNQIE 176
Query: 665 LNLNLQQPELFKFCRENDIVVMAYTP 742
+N+ QQP L +FC++ ++ V AY P
Sbjct: 177 VNVYCQQPRLLEFCKKLNLHVTAYCP 202
>UniRef50_A7RRF6 Cluster: Predicted protein; n=2; Nematostella
vectensis|Rep: Predicted protein - Nematostella
vectensis
Length = 275
Score = 119 bits (287), Expect = 9e-26
Identities = 64/172 (37%), Positives = 100/172 (58%)
Frame = +2
Query: 227 TEQAVIYALEAGYTHIDTAYKYGIEDQVGRALTKKFSEGLKRESIFITTKLWNSYHEREQ 406
T+QAV++ALE GY IDTA Y E +VG AL + + R +++ TK++++ H E+
Sbjct: 30 TKQAVLWALENGYRMIDTAASYNNEKRVGEALRES---AVPRSEVYLVTKVYHTDHGYEK 86
Query: 407 VIPALRKSLENLNLEYVDLYLIHWPIAMFENDTLLDNVDFLDTWRGMIDAKKLGLTKSIG 586
+ A +SL L ++YVDLYLIH+P+ + +W M + + GLT+SIG
Sbjct: 87 TMKAYDRSLSALGVDYVDLYLIHFPVP----------AGVVGSWEAMAELQGKGLTRSIG 136
Query: 587 ISNFNQEQIQRIIDSGLEXPSALQIELNLNLQQPELFKFCRENDIVVMAYTP 742
+SNFN ++ + + P QIE++ LQ EL FCR++ I + AY+P
Sbjct: 137 VSNFNIHHLEALQKHSVIPPVVNQIEVHPYLQMEELVDFCRKHSIAIQAYSP 188
>UniRef50_A0JRJ3 Cluster: 2,5-didehydrogluconate reductase; n=3;
Actinobacteria (class)|Rep: 2,5-didehydrogluconate
reductase - Arthrobacter sp. (strain FB24)
Length = 276
Score = 119 bits (286), Expect = 1e-25
Identities = 71/209 (33%), Positives = 111/209 (53%)
Frame = +2
Query: 125 PTLQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIED 304
P ++L+ G IP + LGTW P + AV+ A+E GY HIDTA KYG E
Sbjct: 5 PVIELNDGHRIPQIGLGTW----PLDD-----HQVAAAVVNAVEGGYRHIDTAVKYGNEK 55
Query: 305 QVGRALTKKFSEGLKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPI 484
VG + S GL R +FITTKL + +++ + L SL+ L L+YVDL LIHWP+
Sbjct: 56 GVGNGIR---SSGLDRSELFITTKLDGEFQGQDRAVAGLDGSLKRLGLDYVDLLLIHWPL 112
Query: 485 AMFENDTLLDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGLEXPSALQIE 664
+ +F+ TW+ + G +SIG+SNF ++R++ + P+ QI+
Sbjct: 113 PRRD--------EFISTWKTFERLQADGKVRSIGVSNFKPAHLERLMAACDVVPAVNQIQ 164
Query: 665 LNLNLQQPELFKFCRENDIVVMAYTPFGS 751
++ + + + R + IV +Y+P G+
Sbjct: 165 VSPAITRIVDIAYNRRHGIVTESYSPLGA 193
>UniRef50_Q8J0K1 Cluster: 4-dihydromethyltrisporate dehydrogenase;
n=2; Parasitella parasitica|Rep:
4-dihydromethyltrisporate dehydrogenase - Parasitella
parasitica
Length = 321
Score = 119 bits (286), Expect = 1e-25
Identities = 71/192 (36%), Positives = 104/192 (54%), Gaps = 17/192 (8%)
Frame = +2
Query: 224 DTEQAVIYALEAGYTHIDTAYKYGIEDQVGRALTKKFSEGL-KRESIFITTKLWNSYHER 400
D E + A++ GY D A YG E +VGR + K EGL KRE +FI TKLWN++H +
Sbjct: 29 DAENTIYQAIKIGYRLFDGACDYGNEVEVGRGINKAIKEGLVKREELFIVTKLWNTFHSK 88
Query: 401 EQVIPALRKSLENLNLEYVDLYLIHWPIAMFENDTLL-----------DNVDF-----LD 532
+ V A + L++ LEY DLYLIH+PI + D + D ++F +
Sbjct: 89 QHVRTAFDRQLKDWGLEYFDLYLIHFPIPLQYVDPAVSYPPEWYVPHADKLNFERSPIHE 148
Query: 533 TWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGLEXPSALQIELNLNLQQPELFKFCRE 712
W M + LT++IG++NFN + I ++ P+ LQIE++ L Q L K+ +E
Sbjct: 149 CWAEMEKLVQAKLTRNIGVANFNCQAILDLLSYAKIKPAVLQIEIHPLLPQERLVKWVQE 208
Query: 713 NDIVVMAYTPFG 748
I V AY+ FG
Sbjct: 209 QGIQVTAYSSFG 220
>UniRef50_Q5TNP1 Cluster: ENSANGP00000029046; n=2; Culicidae|Rep:
ENSANGP00000029046 - Anopheles gambiae str. PEST
Length = 331
Score = 118 bits (285), Expect = 2e-25
Identities = 81/231 (35%), Positives = 126/231 (54%), Gaps = 14/231 (6%)
Frame = +2
Query: 128 TLQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQ 307
T +L++G +IP+ GT+ H + + QV + YALEAGY HIDTA Y E+
Sbjct: 33 TFKLNTGFDIPLAGFGTYQIHGQE-LIYQVLD-------YALEAGYRHIDTAVVYRNEEY 84
Query: 308 VGRALTKKFSE-GLKRESIFITTKLWNSYHEREQVIPAL-RKSLENLNLEYVDLYLIHWP 481
+G AL + LKRE IFIT+KL + + E + + RKSL NL +Y+DLYLIHWP
Sbjct: 85 IGTALKTLLPKYNLKREDIFITSKLISQSGKDEAFVEQMVRKSLANLQTDYLDLYLIHWP 144
Query: 482 IA---------MFEND-TLLDNVDF-LDTWRGMIDAKKLGLTKSIGISNFNQEQIQRII- 625
+F T DNV + +W + ++ G +SIG+SN+ + ++ ++
Sbjct: 145 GVSGKCGRWKWLFGMQVTHPDNVKYRAASWNALSKLEREGCLRSIGVSNYTVKHLKEMLA 204
Query: 626 DSGLEXPSALQIELNLNLQQPELFKFCRENDIVVMAYTPFGSLFPSKAQPD 778
D P+ Q+E + QPEL ++CR++ I + AY+ GS ++ + D
Sbjct: 205 DCKGIVPAVNQVEWHPYYYQPELLEYCRQHGIFLQAYSSLGSSNTAELRED 255
>UniRef50_Q9P6D3 Cluster: Related to aldo-keto reductase YPR1; n=10;
Pezizomycotina|Rep: Related to aldo-keto reductase YPR1
- Neurospora crassa
Length = 322
Score = 118 bits (284), Expect = 2e-25
Identities = 80/230 (34%), Positives = 117/230 (50%), Gaps = 8/230 (3%)
Frame = +2
Query: 119 IVPTLQLSSGGNIPVVALGTWLGHRPKGKVVQ-VTNDTEQAVIYALEAGYTHIDTAYKYG 295
++P+L+LS G IP++ G + G ++ A + AL AGY H+D A YG
Sbjct: 23 LIPSLKLSDGNEIPMLGYGLGTANYKSGDSADTISEPIVNATLTALNAGYAHLDGAEVYG 82
Query: 296 IEDQVGRALTKKFSEGLKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIH 475
E ++GRA+ + L R S++ITTK + V + +SLE L L+YVDLYL+H
Sbjct: 83 NEVELGRAIAQ---SKLPRSSLYITTK--TIVRAGDTVTQSFNRSLEKLGLDYVDLYLLH 137
Query: 476 WPIAMFENDTLLDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIID--SGLEXPS 649
P +N L WR M K G+ KSIG+SNF +Q + D GL+ P
Sbjct: 138 SPF-FAKNPEQLQ-----AAWREMEKIKDSGMAKSIGVSNFLISHLQTLFDIPGGLQYPP 191
Query: 650 AL-QIELNLNLQQ----PELFKFCRENDIVVMAYTPFGSLFPSKAQPDAP 784
+ QIE + LQ +L FCRE I + AY+P ++ ++ P P
Sbjct: 192 VVNQIEYHPYLQHVVEGEDLVAFCREKHIAIAAYSPLTAITKARPGPVDP 241
>UniRef50_A2UAH0 Cluster: Aldo/keto reductase; n=1; Bacillus
coagulans 36D1|Rep: Aldo/keto reductase - Bacillus
coagulans 36D1
Length = 273
Score = 118 bits (283), Expect = 3e-25
Identities = 69/210 (32%), Positives = 112/210 (53%), Gaps = 2/210 (0%)
Frame = +2
Query: 128 TLQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQ 307
T L +G IP + LGTW P G+ T AV +AL+ GY HIDTAY Y E+
Sbjct: 7 TFVLENGVAIPKIGLGTW--QVPNGET------TYHAVSFALKNGYRHIDTAYAYHNEES 58
Query: 308 VGRALTKKFSEGLKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIH--WP 481
VG+A+ G+ R IF+T+KL ++ + +++ N LE +DLYLIH WP
Sbjct: 59 VGKAVR---DSGIDRRDIFVTSKLPAEIKSYDKALKTFDETMGNFGLEQLDLYLIHAPWP 115
Query: 482 IAMFENDTLLDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGLEXPSALQI 661
+ D +N++ W+ M + + G ++IG+SNF+ ++ ++++ P QI
Sbjct: 116 WSEKGADYTKENIE---VWKAMEEIYESGRCRAIGVSNFSVSDLKAVMENAKIKPMVNQI 172
Query: 662 ELNLNLQQPELFKFCRENDIVVMAYTPFGS 751
+ Q ++ FC++N I+V AY+P +
Sbjct: 173 RYFIGHTQEDVTAFCQDNGILVEAYSPLAT 202
>UniRef50_Q8ET73 Cluster: 2,5-diketo-D-gluconate reductase; n=12;
Bacteria|Rep: 2,5-diketo-D-gluconate reductase -
Oceanobacillus iheyensis
Length = 280
Score = 117 bits (281), Expect = 5e-25
Identities = 72/207 (34%), Positives = 113/207 (54%)
Frame = +2
Query: 122 VPTLQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIE 301
+P + L G IP V GT+ R G ND QA+ A++ GY IDTAY Y E
Sbjct: 5 IPNVTLHDGLTIPKVGFGTY---RLNG------NDGVQAINNAIDHGYRLIDTAYNYENE 55
Query: 302 DQVGRALTKKFSEGLKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWP 481
VG A+ + + RE + IT+KL YH ++ + +++SL NL+Y DLYLIHWP
Sbjct: 56 GTVGEAVRRSSTP---REQLLITSKLPGRYHHYDKAVTTIQESLYRANLDYYDLYLIHWP 112
Query: 482 IAMFENDTLLDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGLEXPSALQI 661
+ + D +++ W+ +I+AK+ G +SIG+ NF E ++R+ E P+ QI
Sbjct: 113 ------NPIQD--IYVEAWQALIEAKRRGYIRSIGVCNFLPEHLERLKQETGELPTINQI 164
Query: 662 ELNLNLQQPELFKFCRENDIVVMAYTP 742
EL+ Q + K+ +E+ I +++P
Sbjct: 165 ELHPFFNQEDQRKWHQEHQIATESWSP 191
>UniRef50_Q7NB44 Cluster: ARA1; n=3; Firmicutes|Rep: ARA1 -
Mycoplasma gallisepticum
Length = 289
Score = 117 bits (281), Expect = 5e-25
Identities = 69/173 (39%), Positives = 99/173 (57%)
Frame = +2
Query: 227 TEQAVIYALEAGYTHIDTAYKYGIEDQVGRALTKKFSEGLKRESIFITTKLWNSYHEREQ 406
T +AV ALE GY H+D A Y E+Q+ + K S G+ R+ IFIT+K+WN E
Sbjct: 38 TVEAVKTALEVGYRHLDCAEIY--ENQLSVSQGIKLS-GVNRKEIFITSKIWNDDKGYES 94
Query: 407 VIPALRKSLENLNLEYVDLYLIHWPIAMFENDTLLDNVDFLDTWRGMIDAKKLGLTKSIG 586
A K L++L+LEY+DL LIHWPI D V+ TW+ M + G K+IG
Sbjct: 95 TKKAFHKILKDLDLEYLDLLLIHWPIGKGFKDN-WQEVN-AQTWKAMEEFYLEGKIKAIG 152
Query: 587 ISNFNQEQIQRIIDSGLEXPSALQIELNLNLQQPELFKFCRENDIVVMAYTPF 745
+SNF I+ + S P Q+E + QPE+ ++C++N+IVV A++PF
Sbjct: 153 LSNFLVHHIEALKKSAKILPMVNQLEFHPGYLQPEIVEYCQKNNIVVQAWSPF 205
>UniRef50_Q6U5V3 Cluster: Putative uncharacterized protein; n=1;
Klebsiella pneumoniae|Rep: Putative uncharacterized
protein - Klebsiella pneumoniae
Length = 279
Score = 117 bits (281), Expect = 5e-25
Identities = 64/176 (36%), Positives = 106/176 (60%)
Frame = +2
Query: 224 DTEQAVIYALEAGYTHIDTAYKYGIEDQVGRALTKKFSEGLKRESIFITTKLWNSYHERE 403
D + + AL+AG+ H DTA Y ED VGRAL +++E + RE +FIT+K+
Sbjct: 28 DVDSLIRQALKAGFRHFDTAQAYFNEDGVGRAL--RYTE-VPREQLFITSKIRGRDMGYA 84
Query: 404 QVIPALRKSLENLNLEYVDLYLIHWPIAMFENDTLLDNVDFLDTWRGMIDAKKLGLTKSI 583
+ + + ++LE L +EY++L+LIHWPI N+ +++TW I+ + GL +SI
Sbjct: 85 RTLVSFNETLERLGVEYLELFLIHWPIPA-------KNL-YVETWEASIELEASGLIRSI 136
Query: 584 GISNFNQEQIQRIIDSGLEXPSALQIELNLNLQQPELFKFCRENDIVVMAYTPFGS 751
G+SNF + I+R+I+ P+ Q+EL+ + QQ ++ + E I + +Y+PFGS
Sbjct: 137 GVSNFTCQHIERLIEDTGVVPAVNQLELHPHFQQCDVRDYHHEAGIAIQSYSPFGS 192
>UniRef50_Q18483 Cluster: Putative uncharacterized protein; n=2;
Caenorhabditis|Rep: Putative uncharacterized protein -
Caenorhabditis elegans
Length = 287
Score = 117 bits (281), Expect = 5e-25
Identities = 66/201 (32%), Positives = 107/201 (53%), Gaps = 1/201 (0%)
Frame = +2
Query: 152 NIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQVGRALTKK 331
N+P++ +GTW VQ Q + + GY IDTA Y E ++GR L K
Sbjct: 10 NMPLIGIGTWQ--------VQKEEILRQVIDAGFKEGYRFIDTAQVYNNEAKIGRILEKL 61
Query: 332 F-SEGLKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPIAMFENDTL 508
+ GLKRE I+IT+KL S ++ ++ +SL NL +EY+DL LIHWP + +++
Sbjct: 62 LPANGLKREDIWITSKLAPSNAGVKKARESIEESLSNLKVEYLDLLLIHWPGSSLKSENP 121
Query: 509 LDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGLEXPSALQIELNLNLQQP 688
+ +++W M + G +S+G+SNF ++ + P+ Q+E + + Q
Sbjct: 122 ANKKLRVESWNVMCEMMAEGKLRSVGVSNFEICHLEELKKDSNVVPAVNQVEYHPHFHQD 181
Query: 689 ELFKFCRENDIVVMAYTPFGS 751
+L K+C EN+I AY+ GS
Sbjct: 182 DLVKYCNENNIHFQAYSSLGS 202
>UniRef50_P38115 Cluster: D-arabinose dehydrogenase [NAD(P)+] heavy
chain; n=3; Saccharomycetaceae|Rep: D-arabinose
dehydrogenase [NAD(P)+] heavy chain - Saccharomyces
cerevisiae (Baker's yeast)
Length = 344
Score = 116 bits (280), Expect = 6e-25
Identities = 85/230 (36%), Positives = 129/230 (56%), Gaps = 25/230 (10%)
Frame = +2
Query: 137 LSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQVGR 316
L++G IP + LGT P K+ + T+QAV A++AGY HIDTA+ Y E VG
Sbjct: 27 LNNGVRIPALGLGT---ANPHEKLAE----TKQAVKAAIKAGYRHIDTAWAYETEPFVGE 79
Query: 317 ALTKKFSEG-LKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPIAMF 493
A+ + +G +KRE +FITTK+W ++V +L +SL+ L LEYVDL L HWP+ F
Sbjct: 80 AIKELLEDGSIKREDLFITTKVWPVLW--DEVDRSLNESLKALGLEYVDLLLQHWPLC-F 136
Query: 494 EN-----------DTLLDNV---------DFLDTWRGM----IDAKKLGLTKSIGISNFN 601
E T +D+ D+L+T++ + +D ++IG+SNF+
Sbjct: 137 EKIKDPKGISGLVKTPVDDSGKTMYAADGDYLETYKQLEKIYLDPND-HRVRAIGVSNFS 195
Query: 602 QEQIQRIIDSGLEXPSALQIELNLNLQQPELFKFCRENDIVVMAYTPFGS 751
E ++R+I P+ Q+E + +L Q EL KFC +DI++ AY+P GS
Sbjct: 196 IEYLERLIKECRVKPTVNQVETHPHLPQMELRKFCFMHDILLTAYSPLGS 245
>UniRef50_Q5K8C5 Cluster: Aldo-keto reductase, putative; n=1;
Filobasidiella neoformans|Rep: Aldo-keto reductase,
putative - Cryptococcus neoformans (Filobasidiella
neoformans)
Length = 303
Score = 116 bits (279), Expect = 8e-25
Identities = 66/174 (37%), Positives = 100/174 (57%), Gaps = 1/174 (0%)
Frame = +2
Query: 224 DTEQAVIYALEAGYTHIDTAYKYGIEDQVGRALTKKF-SEGLKRESIFITTKLWNSYHER 400
+T V +ALEAGY H+DTA Y E G+A+ + G RE IF+T+KL N+
Sbjct: 55 ETYDCVKWALEAGYRHVDTAEWYENEAPCGKAIADFLKATGTSREEIFLTSKLKNN-SSY 113
Query: 401 EQVIPALRKSLENLNLEYVDLYLIHWPIAMFENDTLLDNVDFLDTWRGMIDAKKLGLTKS 580
EQ L+ SL+ +EY DLYL+H I + NV W+ + DA+ GL KS
Sbjct: 114 EQAFVDLKGSLKRSGVEYFDLYLMHSAIG---GPVIRKNV-----WKALCDAQSQGLVKS 165
Query: 581 IGISNFNQEQIQRIIDSGLEXPSALQIELNLNLQQPELFKFCRENDIVVMAYTP 742
IG+SNF ++ IQ ID + P+ Q++L+ ++ PE+ + C +N+I++ A+ P
Sbjct: 166 IGVSNFGKKHIQEFIDQKVPLPTVNQVDLHPFMRHPEIVEICEQNEILLEAWGP 219
>UniRef50_Q4JX70 Cluster: Putative oxidoreductase; n=1;
Corynebacterium jeikeium K411|Rep: Putative
oxidoreductase - Corynebacterium jeikeium (strain K411)
Length = 285
Score = 116 bits (278), Expect = 1e-24
Identities = 74/211 (35%), Positives = 113/211 (53%), Gaps = 2/211 (0%)
Frame = +2
Query: 122 VPTLQLSSGGNIPVVALGTWLGHRPKGKVVQVTN-DTEQAVIYALEAGYTHIDTAYKYGI 298
VPTL+++ G P + LG W Q+++ DT +V A+E GY HIDTA YG
Sbjct: 8 VPTLEMNDGKTTPQLGLGVW----------QLSDEDTYTSVRAAIETGYRHIDTAAIYGN 57
Query: 299 EDQVGRALTKKFSEG-LKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIH 475
E+ VGRA+ G ++RE +FITTKLWN+ ++ A +S + L ++YVDLYL+H
Sbjct: 58 EEAVGRAVADAVKAGDVQREELFITTKLWNA--DQACGKEAFAESQKKLGMDYVDLYLLH 115
Query: 476 WPIAMFENDTLLDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGLEXPSAL 655
WP ++ F+ + M + ++ G SIG+ NF E + + +G P+
Sbjct: 116 WPCPQADS--------FVQAYDSMAEIQQSGGATSIGVCNFYPEALDALKQAG-HTPAVN 166
Query: 656 QIELNLNLQQPELFKFCRENDIVVMAYTPFG 748
QIE++ Q E R+ IV A++P G
Sbjct: 167 QIEIHPGFSQAEQRSDNRDRGIVTEAWSPLG 197
>UniRef50_Q4PDR0 Cluster: Putative uncharacterized protein; n=1;
Ustilago maydis|Rep: Putative uncharacterized protein -
Ustilago maydis (Smut fungus)
Length = 339
Score = 115 bits (277), Expect = 1e-24
Identities = 72/226 (31%), Positives = 116/226 (51%), Gaps = 17/226 (7%)
Frame = +2
Query: 122 VPTLQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIE 301
+P+ L++G +P V +G W G G+ N+ A++ A++ GY H+DTA Y E
Sbjct: 5 IPSFTLNTGAKLPSVGMGCWQGQPGPGR----DNELVDALVRAIKVGYRHLDTATGYRNE 60
Query: 302 DQVGRALTKKFSEGLKRESIFITTKLW-NSYHEREQVIPALRKSLENLNLEYVDLYLIHW 478
+VG+A+ + G+ R IF+TTKL H+ V+ L SL L ++Y+DL+L+HW
Sbjct: 61 AEVGQAVRQS---GVARSEIFVTTKLRPGGVHD---VVQELENSLNELGIDYIDLWLLHW 114
Query: 479 PIAMFENDTLLDNVD-------------FLDTWRGMIDA---KKLGLTKSIGISNFNQEQ 610
P ++D + F +TW M D G K+IG+SNF+ +
Sbjct: 115 PQGFTKDDGGFGTGESFGLEHQKHLGPTFNETWAKMEDVFLNSHKGKVKAIGVSNFSIKN 174
Query: 611 IQRIIDSGLEXPSALQIELNLNLQQPELFKFCRENDIVVMAYTPFG 748
++ + + P+ QIE + L + EL K+C+ I V AY+P G
Sbjct: 175 LEILAKTSKVTPAVNQIEAHPYLPEHELVKYCKHKSIHVTAYSPLG 220
>UniRef50_Q4P4P1 Cluster: Putative uncharacterized protein; n=1;
Ustilago maydis|Rep: Putative uncharacterized protein -
Ustilago maydis (Smut fungus)
Length = 322
Score = 115 bits (277), Expect = 1e-24
Identities = 74/215 (34%), Positives = 117/215 (54%), Gaps = 3/215 (1%)
Frame = +2
Query: 107 SADLIVPTLQLSSGGNIPVVALGTWLGHRPKGKVVQVTND--TEQAVIYALEAGYTHIDT 280
S ++ ++L++G IP VALG V + ND TE A +A +AGY HID+
Sbjct: 11 SGNISTQRIKLNNGQEIPQVALG----------VYKAPNDGSTENACKWAFDAGYRHIDS 60
Query: 281 AYKYGIEDQVGRALTKKFSEG-LKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYV 457
A +Y E+ VGRAL + E + R IFIT+KLW++ H++ A+ SL+ LN++Y+
Sbjct: 61 AARYMNEESVGRALAEWTKENNVPRSEIFITSKLWDADHDKAAA--AIEDSLKKLNVDYM 118
Query: 458 DLYLIHWPIAMFENDTLLDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGL 637
D+YL+H P M L + W+ + +A G K+IG+SNF+ E++ ++ +
Sbjct: 119 DMYLMHSPGTMGAEKRL-------EAWKALEEAVDAGKIKTIGVSNFDVEELDHLLANCR 171
Query: 638 EXPSALQIELNLNLQQPELFKFCRENDIVVMAYTP 742
P+ QIE + EL + C I + AY+P
Sbjct: 172 IKPAVNQIESHPFFAHEELREACISRGIHIQAYSP 206
>UniRef50_Q15NA5 Cluster: Aldo/keto reductase; n=2;
Gammaproteobacteria|Rep: Aldo/keto reductase -
Pseudoalteromonas atlantica (strain T6c / BAA-1087)
Length = 273
Score = 114 bits (275), Expect = 2e-24
Identities = 65/177 (36%), Positives = 98/177 (55%), Gaps = 1/177 (0%)
Frame = +2
Query: 221 NDTEQAVIYALEAGYTHIDTAYKYGIEDQVGRALTKKFSEGLKRESIFITTKLWNSYHER 400
+D + AV AL+ GY HIDTA Y E +VG A++ + + R +F+TTK+W
Sbjct: 24 DDAKLAVENALDVGYRHIDTAQAYENEAEVGDAIS---ASKISRGELFVTTKVWFDNLSA 80
Query: 401 EQVIPALRKSLENLNLEYVDLYLIHWPIAMFENDTLLDNVDFLDTWRGMIDAKKLGLTKS 580
++ I +++ SL LN +YVDL L+HWP D + ++L + K+ GLT+
Sbjct: 81 DKFITSVQNSLTQLNTDYVDLLLVHWP----SPDNKVSMAEYLKELKA---CKERGLTRH 133
Query: 581 IGISNFNQEQIQRIID-SGLEXPSALQIELNLNLQQPELFKFCRENDIVVMAYTPFG 748
IG+SNF Q Q+ + G + QIE++ N Q EL +C+ N+I V AY P G
Sbjct: 134 IGVSNFTQSQLDEALSILGKDHILTNQIEVHPNFQNKELVAYCQRNNIQVTAYMPLG 190
>UniRef50_Q838E0 Cluster: Oxidoreductase, aldo/keto reductase
family; n=24; Bacilli|Rep: Oxidoreductase, aldo/keto
reductase family - Enterococcus faecalis (Streptococcus
faecalis)
Length = 279
Score = 114 bits (274), Expect = 3e-24
Identities = 69/209 (33%), Positives = 109/209 (52%), Gaps = 1/209 (0%)
Frame = +2
Query: 119 IVPTLQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGI 298
+ T+ L++G IP + LG + P + +V E+ +I GY IDTA YG
Sbjct: 5 LADTVTLNNGTKIPGMGLGVF--QIPDEETAKVV---EEGIIN----GYRLIDTAQIYGN 55
Query: 299 EDQVGRALTKKFSE-GLKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIH 475
E G + + GL RE +F+T+K+WN++ ++ I A SLE L L+Y+DLYLIH
Sbjct: 56 ESGTGAGIKAGLAATGLNREDLFVTSKVWNAHISYDETIQAFNDSLERLGLDYLDLYLIH 115
Query: 476 WPIAMFENDTLLDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGLEXPSAL 655
WP N + ++W+ + G K+IG+SNF ++ ++ P
Sbjct: 116 WP----------GNNSYKESWQALETLYAEGKVKAIGVSNFQVHHLEDLLSYAKVVPVIN 165
Query: 656 QIELNLNLQQPELFKFCRENDIVVMAYTP 742
Q+EL+ L Q E+ FC ++DI V A++P
Sbjct: 166 QVELHPKLDQKEVRDFCEKHDIKVQAWSP 194
>UniRef50_Q043M4 Cluster: Aldo/keto reductase of diketogulonate
reductase family; n=2; Lactobacillus|Rep: Aldo/keto
reductase of diketogulonate reductase family -
Lactobacillus gasseri (strain ATCC 33323 / DSM 20243)
Length = 273
Score = 114 bits (274), Expect = 3e-24
Identities = 70/177 (39%), Positives = 99/177 (55%)
Frame = +2
Query: 221 NDTEQAVIYALEAGYTHIDTAYKYGIEDQVGRALTKKFSEGLKRESIFITTKLWNSYHER 400
+ T+QAV+ A E GY IDTA Y E QVG A+ + GL R+ +FITTK +E
Sbjct: 25 DQTKQAVLSAFEEGYRLIDTAQYYQNEQQVGEAVK---ASGLNRDEVFITTKTMTDGYED 81
Query: 401 EQVIPALRKSLENLNLEYVDLYLIHWPIAMFENDTLLDNVDFLDTWRGMIDAKKLGLTKS 580
++ L +SL + L+Y DL LIHWP+ +D +DTW + A K G T++
Sbjct: 82 TKI--GLDESLRRIGLDYFDLVLIHWPMG---HD--------IDTWHALEAAYKAGKTRA 128
Query: 581 IGISNFNQEQIQRIIDSGLEXPSALQIELNLNLQQPELFKFCRENDIVVMAYTPFGS 751
IGISNFN Q +I P QIE +L LQQ ++ +F + +IV +Y+P G+
Sbjct: 129 IGISNFNSRQTLDLIHQSSVRPMVDQIETHLFLQQWKMHEFLEKENIVHESYSPLGN 185
>UniRef50_P47137 Cluster: Probable oxidoreductase YJR096W; n=8;
Saccharomycetales|Rep: Probable oxidoreductase YJR096W -
Saccharomyces cerevisiae (Baker's yeast)
Length = 282
Score = 114 bits (274), Expect = 3e-24
Identities = 75/209 (35%), Positives = 115/209 (55%), Gaps = 6/209 (2%)
Frame = +2
Query: 134 QLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQVG 313
+LS+G IP +ALGT+ P+ + ++ V ++ GY H DTA YG E +VG
Sbjct: 7 KLSNGFKIPSIALGTY--DIPRSQTAEI-------VYEGVKCGYRHFDTAVLYGNEKEVG 57
Query: 314 RALTKKFSE---GLKRESIFITTKLWNSYHEREQVIPALRKSLENLN-LEYVDLYLIHWP 481
+ K +E KRE IF TTKLWNS + ++ A+R+ L ++ L+Y+DL LIH P
Sbjct: 58 DGIIKWLNEDPGNHKREEIFYTTKLWNSQNGYKRAKAAIRQCLNEVSGLQYIDLLLIHSP 117
Query: 482 IAMFENDTLLDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIID--SGLEXPSAL 655
+ E L L+TWR M +A GL KSIG+SN+ ++ I +++ P
Sbjct: 118 L---EGSKLR-----LETWRAMQEAVDEGLVKSIGVSNYGKKHIDELLNWPELKHKPVVN 169
Query: 656 QIELNLNLQQPELFKFCRENDIVVMAYTP 742
QIE++ + + EL +C+ +VV A+ P
Sbjct: 170 QIEISPWIMRQELADYCKSKGLVVEAFAP 198
>UniRef50_Q5BLA6 Cluster: Zgc:110782; n=2; Danio rerio|Rep:
Zgc:110782 - Danio rerio (Zebrafish) (Brachydanio rerio)
Length = 287
Score = 113 bits (272), Expect = 6e-24
Identities = 76/213 (35%), Positives = 112/213 (52%), Gaps = 2/213 (0%)
Frame = +2
Query: 116 LIVPTLQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYG 295
+IVP+++L SG +P++ LGT+ +Q +Q+V AL+AGY DTA YG
Sbjct: 1 MIVPSVRLMSGTQMPLLGLGTYK--------LQDHEQLKQSVSCALQAGYRAFDTAAVYG 52
Query: 296 IEDQVGRALTKKFSE-GLKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLI 472
E +G+ L + + GL RE +FI +KL S H LR SLE L+ EY+DLYLI
Sbjct: 53 NEAHLGQVLKELLPKYGLIREDVFIISKLAPSDHGLRAKEGCLR-SLEQLDCEYIDLYLI 111
Query: 473 HWP-IAMFENDTLLDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGLEXPS 649
HWP + + + + +W + + G K+IG+SN+ + I+ ++ S P+
Sbjct: 112 HWPGMEGLDPEDSRHSEYRAQSWATLEEFHASGQFKAIGVSNYTAKHIRELLASCRVPPA 171
Query: 650 ALQIELNLNLQQPELFKFCRENDIVVMAYTPFG 748
LQIE L Q EL C E I AY+ G
Sbjct: 172 VLQIECQPKLIQRELRDLCMETGIHFQAYSSLG 204
>UniRef50_A0JRJ6 Cluster: Aldo/keto reductase; n=2;
Micrococcineae|Rep: Aldo/keto reductase - Arthrobacter
sp. (strain FB24)
Length = 281
Score = 113 bits (272), Expect = 6e-24
Identities = 78/210 (37%), Positives = 111/210 (52%), Gaps = 1/210 (0%)
Frame = +2
Query: 122 VPTLQLSSGGNIPVVALGTWLGHRPKGKVVQVT-NDTEQAVIYALEAGYTHIDTAYKYGI 298
+P L L++G IP + G V QV +T++ V ALEAGY HIDTA Y
Sbjct: 9 IPQLTLNNGVKIPQLGFG----------VFQVPPEETQRIVEDALEAGYRHIDTAAAYRN 58
Query: 299 EDQVGRALTKKFSEGLKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHW 478
E VG A++ + G+ RE IFITTKL N E+ A + S + L +E+VDLYLIHW
Sbjct: 59 EAGVGAAIS---ASGIPREDIFITTKLRNG--EQGNAHEAFQNSRKALGVEFVDLYLIHW 113
Query: 479 PIAMFENDTLLDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGLEXPSALQ 658
P+ + L + + W+ M ++IG+SNF E + ++ + P+ Q
Sbjct: 114 PVP---SQGL-----YTEAWKAMEKLYANSQIRAIGVSNFLGEHLDTLLPAADVVPAVNQ 165
Query: 659 IELNLNLQQPELFKFCRENDIVVMAYTPFG 748
+E++ QQ EL CRE I V AY+P G
Sbjct: 166 VEIHPTFQQQELAAKCRELGIAVEAYSPLG 195
>UniRef50_Q76L37 Cluster: Conjugated polyketone reductase C1; n=3;
Saccharomycetales|Rep: Conjugated polyketone reductase
C1 - Candida parapsilosis (Yeast)
Length = 304
Score = 113 bits (272), Expect = 6e-24
Identities = 78/228 (34%), Positives = 121/228 (53%), Gaps = 14/228 (6%)
Frame = +2
Query: 134 QLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVI----YALEAGYTHIDTAYKYGIE 301
+LS+G IP VA GT + +G ND ++ +I AL +G+ HID A YG
Sbjct: 9 KLSNGNKIPAVAFGTGTKYFKRGH-----NDLDKQLIGTLELALRSGFRHIDGAEIYGTN 63
Query: 302 DQVGRALTKKFSEGLKRESIFITTKL------WNSYHEREQ-VIPALRKSLENLNLEYVD 460
++G AL + GL R+ +FIT K ++ H + Q AL+ LE+L LEYVD
Sbjct: 64 KEIGIALK---NVGLNRKDVFITDKYNSGNHTYDGKHSKHQNPYNALKADLEDLGLEYVD 120
Query: 461 LYLIHWPIAMFENDTLLDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGLE 640
LYLIH+P ++ D ++ WR + AK GL ++IG+SNF E ++ I+D+ +
Sbjct: 121 LYLIHFPYISEKSH----GFDLVEAWRYLERAKNEGLARNIGVSNFTIENLKSILDANTD 176
Query: 641 -XPSALQIELNLNLQQ--PELFKFCRENDIVVMAYTPFGSLFPSKAQP 775
P QIE + LQ P + ++ ++ I++ AY P G + + P
Sbjct: 177 SIPVVNQIEFSAYLQDQTPGIVEYSQQQGILIEAYGPLGPITQGRPGP 224
>UniRef50_A6NPD6 Cluster: Putative uncharacterized protein; n=3;
Bacteria|Rep: Putative uncharacterized protein -
Bacteroides capillosus ATCC 29799
Length = 287
Score = 113 bits (271), Expect = 8e-24
Identities = 72/207 (34%), Positives = 108/207 (52%), Gaps = 3/207 (1%)
Frame = +2
Query: 137 LSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIY-ALEAGYTHIDTAYKYGIEDQVG 313
LS+G +IP V GT+ T D + AV+ A+ GY H DTA YG E +G
Sbjct: 10 LSNGLSIPAVGFGTYK-----------TGDGDSAVLSNAIAQGYRHFDTASFYGTETALG 58
Query: 314 RALTKKFSEGLKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPIAMF 493
+A+ + + RE F+T+KLW + + + A +LE L +Y+DLYLIHWP
Sbjct: 59 QAVAES---DIPREDFFLTSKLWKTEMGYDAALRAFDATLERLGTDYLDLYLIHWP---- 111
Query: 494 ENDTLLDNVDFLD--TWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGLEXPSALQIEL 667
D L++ LD TWR + + GL ++IG+SNF ++ I+ S P Q+E
Sbjct: 112 RPDLELEDWAKLDRETWRALERLYESGLVRAIGVSNFLPHHLEPILASANVAPMVDQLEF 171
Query: 668 NLNLQQPELFKFCRENDIVVMAYTPFG 748
+ Q E FC+ + I+V A++P G
Sbjct: 172 HPGYTQDEAVAFCQNHSILVEAWSPLG 198
>UniRef50_Q6CEJ0 Cluster: Yarrowia lipolytica chromosome B of strain
CLIB122 of Yarrowia lipolytica; n=1; Yarrowia
lipolytica|Rep: Yarrowia lipolytica chromosome B of
strain CLIB122 of Yarrowia lipolytica - Yarrowia
lipolytica (Candida lipolytica)
Length = 302
Score = 113 bits (271), Expect = 8e-24
Identities = 79/242 (32%), Positives = 127/242 (52%), Gaps = 6/242 (2%)
Frame = +2
Query: 116 LIVPTLQLSSGGNIPVVALGTWLG-HRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKY 292
+ VP ++LS+G IP + G+ RP G+ + + AV+ A+ AG+ HIDTA Y
Sbjct: 1 MTVPKVKLSNGLEIPAIGFGSGTKWKRPPGEKEE--RELIDAVVSAINAGHLHIDTAEFY 58
Query: 293 GIEDQVGRALTKKFSEGLKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLI 472
G E Q+G A+ + G+ R+ IF+T+K + I ++ L+ L +Y DL+LI
Sbjct: 59 GTEKQIGEAIKE---SGVPRKDIFLTSKTLFGL-LADDPIESISNQLKTLQTDYFDLFLI 114
Query: 473 HWPIAMFENDTLLDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGLEXPSA 652
H P ND + N D W + + GL K+IG+SN + +++ II P
Sbjct: 115 HVP----PNDDI--NYDLAKAWGVLEQLYEKGLAKAIGVSNHSPAELETIIKVAKIKPHV 168
Query: 653 LQIELNLNLQQPE--LFKFCRENDIVVMAYTPFGSLFPSKAQPDAPRRGLTMNVS---SV 817
QIE + LQ+P + FC+++DIVV Y+P S ++ + + P + NV+ +V
Sbjct: 169 NQIEFHPLLQEPTPGIVDFCKQHDIVVEGYSPLAS---NELEGEKPLDAVVANVAKNHNV 225
Query: 818 SP 823
SP
Sbjct: 226 SP 227
>UniRef50_A2QL02 Cluster: Putative frameshift; n=1; Aspergillus
niger|Rep: Putative frameshift - Aspergillus niger
Length = 357
Score = 113 bits (271), Expect = 8e-24
Identities = 74/220 (33%), Positives = 115/220 (52%), Gaps = 11/220 (5%)
Frame = +2
Query: 128 TLQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQ 307
T L++G IP + +GT+ Q + E+ V L+ G IDTA YG+E Q
Sbjct: 37 TYTLNTGAKIPALGVGTF----------QDPDSQEETVCQVLQRGMRLIDTARVYGVEQQ 86
Query: 308 VGRALTKKFSEGLKRESIFITTKLW-NSYHEREQVIPALRKSLENLNLEYVDLYLIHWPI 484
VGR + K G+ RE IF+ TKLW N +H + V A+ SL +L YVDL L+H+P
Sbjct: 87 VGRGIKKS---GVPREEIFLGTKLWCNDFHP-DDVERAVDDSLRDLYTPYVDLLLMHYPC 142
Query: 485 AM------FENDT----LLDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSG 634
F D + F+DTWR + K G ++IG+SNF++ +I+ ++
Sbjct: 143 TFKRGEDRFPRDAEGRMIHGETTFVDTWRALEKVVKTGKVRAIGVSNFSKGEIETLLRET 202
Query: 635 LEXPSALQIELNLNLQQPELFKFCRENDIVVMAYTPFGSL 754
P+ Q+E++ LQQ ++ RE I V+ ++P G++
Sbjct: 203 STVPAVHQMEVHPYLQQKGFNEWLREKGIHVVQFSPLGNM 242
>UniRef50_P15339 Cluster: 2,5-diketo-D-gluconic acid reductase B;
n=6; Actinomycetales|Rep: 2,5-diketo-D-gluconic acid
reductase B - Corynebacterium sp. (strain SHS752001)
Length = 277
Score = 113 bits (271), Expect = 8e-24
Identities = 68/207 (32%), Positives = 113/207 (54%)
Frame = +2
Query: 122 VPTLQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIE 301
+PT+ L+ G LGT+ +G A++ A+++GY +DTA Y E
Sbjct: 4 IPTISLNDGRPFAEPGLGTYNLRGDEGVA---------AMVAAIDSGYRLLDTAVNYENE 54
Query: 302 DQVGRALTKKFSEGLKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWP 481
+VGRA+ + + R+ + + +K+ H R + + ++R SL+ L L+ +DL LIHWP
Sbjct: 55 SEVGRAVR---ASSVDRDELIVASKIPGRQHGRAEAVDSIRGSLDRLGLDVIDLQLIHWP 111
Query: 482 IAMFENDTLLDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGLEXPSALQI 661
N ++ +LDTWRGMIDA++ GL +SIG+SNF + ++ +ID P+ Q+
Sbjct: 112 -----NPSV---GRWLDTWRGMIDAREAGLVRSIGVSNFTEPMLKTLIDETGVTPAVNQV 163
Query: 662 ELNLNLQQPELFKFCRENDIVVMAYTP 742
EL+ Q L F E+ I +++P
Sbjct: 164 ELHPYFPQAALRAFHDEHGIRTESWSP 190
>UniRef50_A0AWM8 Cluster: Aldo/keto reductase; n=4;
Actinomycetales|Rep: Aldo/keto reductase - Arthrobacter
sp. (strain FB24)
Length = 287
Score = 112 bits (269), Expect = 1e-23
Identities = 68/218 (31%), Positives = 114/218 (52%)
Frame = +2
Query: 122 VPTLQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIE 301
+P L+L G IP + LGTW + ++ E AV +AL++GY +DTA++Y E
Sbjct: 13 IPRLKLPHGHTIPRLGLGTW---------PMLEDECETAVRFALQSGYRLVDTAFQYRNE 63
Query: 302 DQVGRALTKKFSEGLKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWP 481
+ VGR + + G+ R +FI++K H + V A +SL L L+++D+++ HWP
Sbjct: 64 EAVGRGIR---TAGVPRSELFISSKFNKESHSIDGVQRAYDESLRKLGLDHLDMFMCHWP 120
Query: 482 IAMFENDTLLDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGLEXPSALQI 661
+ ++D W+G++ + G K+IG+SNF ++ IID+ P QI
Sbjct: 121 VPALGK--------YVDAWKGLVKLLEEGRVKAIGVSNFKPAHLKDIIDATGVVPDVNQI 172
Query: 662 ELNLNLQQPELFKFCRENDIVVMAYTPFGSLFPSKAQP 775
+L+ +L + E R IV A++P G +A P
Sbjct: 173 QLSPDLARTEPRAVHRLLGIVTEAWSPIGRSSGLRANP 210
>UniRef50_Q2U219 Cluster: Aldo/keto reductase family proteins; n=6;
Pezizomycotina|Rep: Aldo/keto reductase family proteins
- Aspergillus oryzae
Length = 294
Score = 112 bits (269), Expect = 1e-23
Identities = 69/221 (31%), Positives = 114/221 (51%)
Frame = +2
Query: 125 PTLQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIED 304
P ++L+ +IP++ GT + V + +A+ A+ GY H+D A YG E
Sbjct: 10 PRVKLNDNVSIPILGYGTGTAWYKQAGDDSVNRELVEAIKTAIRLGYRHLDGAEVYGTEA 69
Query: 305 QVGRALTKKFSEGLKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPI 484
++G A+ + G+ RE +F+TTK+ + + + A+ +SL L L YVDLYLIH P
Sbjct: 70 ELGVAIKES---GIPREELFVTTKVITNIAD---IPSAIDQSLRKLQLNYVDLYLIHSPF 123
Query: 485 AMFENDTLLDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGLEXPSALQIE 664
++D L W M ++ G K+IG+SN++Q ++ + + + P QIE
Sbjct: 124 -FAKSDGELQQA-----WAAMEKVQQAGKAKAIGVSNYHQSHLEATLKTAVIAPVINQIE 177
Query: 665 LNLNLQQPELFKFCRENDIVVMAYTPFGSLFPSKAQPDAPR 787
+ LQQ EL +F RE DI + +Y P + + P P+
Sbjct: 178 HHPYLQQEELLRFQREKDIKIASYGPLTPILRAPGGPVDPK 218
>UniRef50_Q9X0A2 Cluster: Oxidoreductase, aldo/keto reductase
family; n=21; Bacteria|Rep: Oxidoreductase, aldo/keto
reductase family - Thermotoga maritima
Length = 286
Score = 111 bits (268), Expect = 2e-23
Identities = 74/209 (35%), Positives = 110/209 (52%), Gaps = 1/209 (0%)
Frame = +2
Query: 122 VPTLQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIE 301
VP + L++G +P++ G + P K TE+ V A++ GY IDTA Y E
Sbjct: 3 VPKVTLNNGVEMPILGYGVF--QIPPEK-------TEECVYEAIKVGYRLIDTAASYMNE 53
Query: 302 DQVGRALTKKFSEGL-KRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHW 478
+ VGRA+ + EG+ +RE +F+TTKLW S E A KSL+ L LEY+DLYLIH
Sbjct: 54 EGVGRAIKRAIDEGIVRREELFVTTKLWVSDVGYESTKKAFEKSLKKLQLEYIDLYLIHQ 113
Query: 479 PIAMFENDTLLDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGLEXPSALQ 658
P D W+ M + K GL ++IG+SNF +++ ++ P+ Q
Sbjct: 114 PFG-----------DVHCAWKAMEEMYKDGLVRAIGVSNFYPDRLMDLMVHHEIVPAVNQ 162
Query: 659 IELNLNLQQPELFKFCRENDIVVMAYTPF 745
IE++ Q+ E +F R +I A+ PF
Sbjct: 163 IEIHPFYQRQEEIEFMRNYNIQPEAWGPF 191
>UniRef50_Q9ZUJ6 Cluster: T2K10.1 protein; n=16; core
eudicotyledons|Rep: T2K10.1 protein - Arabidopsis
thaliana (Mouse-ear cress)
Length = 176
Score = 111 bits (268), Expect = 2e-23
Identities = 65/178 (36%), Positives = 103/178 (57%), Gaps = 14/178 (7%)
Frame = +2
Query: 122 VPTLQLSSGGN----IPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYK 289
VPTL + SG + +PV+ GT P+ +++ T VI A++ GY H DT+ +
Sbjct: 6 VPTLAIRSGPSGHHSMPVLGFGTAASPLPEPTMLKET------VIEAIKLGYRHFDTSPR 59
Query: 290 YGIEDQVGRALTKKFSEGL--KRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDL 463
Y E+ +G AL + S GL R F+TTKLW + V+PA+++SL+NL L+Y+DL
Sbjct: 60 YQTEEPIGEALAEAVSLGLVRSRSEFFVTTKLWCADAHGGLVVPAIKRSLKNLKLDYLDL 119
Query: 464 YLIHWPIAM--------FENDTLLDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQI 613
Y+IHWP++ + D + +DF W M + ++LGL K IG+SNF+ +++
Sbjct: 120 YIIHWPVSSKPGKYKFPIDEDDFMP-MDFEVVWSEMEECQRLGLAKCIGVSNFSCKKL 176
>UniRef50_UPI00015B5BD7 Cluster: PREDICTED: similar to aldo-keto
reductase; n=1; Nasonia vitripennis|Rep: PREDICTED:
similar to aldo-keto reductase - Nasonia vitripennis
Length = 310
Score = 111 bits (267), Expect = 2e-23
Identities = 69/212 (32%), Positives = 125/212 (58%), Gaps = 5/212 (2%)
Frame = +2
Query: 131 LQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQV 310
L+L++G ++P+V +GT+ + +G+ V ++ + + G+ IDTA Y E+ +
Sbjct: 26 LRLNNGYDMPLVGIGTY---KVRGREV-----IKRVIDESFAVGFRSIDTAVVYRNEEDI 77
Query: 311 GRALTKKFSE-GLKRESIFITTKLWNSYH-EREQVIPALRKSLENLNLEYVDLYLIHWPI 484
G AL + + LKRE IFIT+KL S + + +++ ++ SL+ L+ Y+DLYLIHWP
Sbjct: 78 GLALKELLPKYNLKREDIFITSKLSPSDNGDPDKIRKSVEDSLKALDTSYLDLYLIHWPG 137
Query: 485 AMFENDTLLDNVDF-LDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIID--SGLEXPSAL 655
A + DN + TW +++ ++ GL +SIG+SN+ ++ +++ SG++ P
Sbjct: 138 ASRILENSPDNPKLRVTTWATLVELQQKGLLRSIGVSNYTVGHLEHLLEHCSGVK-PDVN 196
Query: 656 QIELNLNLQQPELFKFCRENDIVVMAYTPFGS 751
Q+E + + +Q EL +FC + I V AY+ G+
Sbjct: 197 QVECHPHFRQDELIEFCTKQGIHVQAYSSLGT 228
>UniRef50_Q07551 Cluster: NADPH-dependent alpha-keto amide
reductase; n=4; Saccharomycetales|Rep: NADPH-dependent
alpha-keto amide reductase - Saccharomyces cerevisiae
(Baker's yeast)
Length = 312
Score = 111 bits (267), Expect = 2e-23
Identities = 74/220 (33%), Positives = 115/220 (52%), Gaps = 5/220 (2%)
Frame = +2
Query: 137 LSSGGNIPVVAL-GTWLG-HRPKGKVVQVTNDTEQAVIYALEA-GYTHIDTAYKYGIEDQ 307
L++G IP +A+ GT ++ + +N + ++YAL+ G HID A Y +
Sbjct: 10 LNNGNKIPAIAIIGTGTRWYKNEETDATFSNSLVEQIVYALKLPGIIHIDAAEIYRTYPE 69
Query: 308 VGRALTKKFSEGLKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPIA 487
VG+AL+ +E R +IF+T K + L +L+ + +YVDLYL+H P
Sbjct: 70 VGKALS--LTEK-PRNAIFLTDKYSPQIKMSDSPADGLDLALKKMGTDYVDLYLLHSPFV 126
Query: 488 MFENDTLLDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGLEXPSALQIEL 667
E ++ + + W+ M K G K+IG+SNF E +QRI+ P QIE
Sbjct: 127 SKE----VNGLSLEEAWKDMEQLYKSGKAKNIGVSNFAVEDLQRILKVAEVKPQVNQIEF 182
Query: 668 N--LNLQQPELFKFCRENDIVVMAYTPFGSLFPSKAQPDA 781
+ L Q P ++KFC+E+DI+V AY+P G L AQ D+
Sbjct: 183 SPFLQNQTPGIYKFCQEHDILVEAYSPLGPLQKKTAQDDS 222
>UniRef50_Q7VG53 Cluster: Aldo-keto reductase; n=28; Bacteria|Rep:
Aldo-keto reductase - Helicobacter hepaticus
Length = 292
Score = 111 bits (266), Expect = 3e-23
Identities = 71/205 (34%), Positives = 112/205 (54%), Gaps = 3/205 (1%)
Frame = +2
Query: 137 LSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQVGR 316
L++G IP + LGTW R VV E AV A + GY HIDTA YG E VG
Sbjct: 17 LNNGNKIPKLGLGTW---RIDDNVV------EAAVREAFKVGYRHIDTAQAYGNERGVGE 67
Query: 317 ALTKKFSEGLKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPI---A 487
A+ K +KRE +FIT+K+ Y + + ++ SL+ + L+++DL LIH P +
Sbjct: 68 AVRKS---KIKREELFITSKIRAEYKDYKSASASIDTSLKTMKLDFIDLMLIHSPQPWNS 124
Query: 488 MFENDTLLDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGLEXPSALQIEL 667
+ D +NV+ + + DA+K G +SIG+SNF Q+ ++ I+ + P+A QI
Sbjct: 125 FRKGDYFKENVE---VYNALEDAQKAGKVRSIGVSNFLQKDLENILKNCKTKPAANQILC 181
Query: 668 NLNLQQPELFKFCRENDIVVMAYTP 742
++ L +C++ +I+ AY+P
Sbjct: 182 HIGNTPFTLLDYCKKQNILAEAYSP 206
>UniRef50_Q1Q8W8 Cluster: Aldo/keto reductase; n=1; Psychrobacter
cryohalolentis K5|Rep: Aldo/keto reductase -
Psychrobacter cryohalolentis (strain K5)
Length = 282
Score = 111 bits (266), Expect = 3e-23
Identities = 79/231 (34%), Positives = 126/231 (54%), Gaps = 8/231 (3%)
Frame = +2
Query: 131 LQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQV 310
++ + NIPV+ LGTW + G+ D V L GY HIDTA YG E +V
Sbjct: 8 IRTAGQANIPVLGLGTW---QSTGQ------DCIDVVSQGLRMGYEHIDTAQAYGNEVEV 58
Query: 311 GRALTKKFSEGLKRESIFITTKLW--NSYHEREQVIPALRKSLENLNLEYVDLYLIHWPI 484
G+ + + G+ R+ F+TTK++ + E E+++ A ++SLENL+ +YVDL L+HWP
Sbjct: 59 GKGIKQS---GVARDKFFLTTKIFPDDMKFEPEKLVAAAKRSLENLDTDYVDLLLLHWPD 115
Query: 485 AMFENDTLLDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSG--LEXPSAL- 655
D V +T + + +K GLT++IG+SNFN I II++ + P +
Sbjct: 116 ---------DRVPLSETIPALCELQKQGLTRNIGVSNFN---IANIIEAKRYADVPIVVN 163
Query: 656 QIELNLNLQQPELFKFCRENDIVVMAYTPF--GSLFPSKAQPD-APRRGLT 799
Q+E + ++Q L F + I++ AY+P G +F +K D A + G+T
Sbjct: 164 QVEFHPFIKQKTLQTFLNNHHILLEAYSPLARGDVFDNKIIKDIADKHGIT 214
>UniRef50_Q5T2L2 Cluster: Aldo-keto reductase family 1 member C-like
protein 1; n=14; Eutheria|Rep: Aldo-keto reductase
family 1 member C-like protein 1 - Homo sapiens (Human)
Length = 302
Score = 111 bits (266), Expect = 3e-23
Identities = 81/259 (31%), Positives = 130/259 (50%), Gaps = 14/259 (5%)
Frame = +2
Query: 128 TLQLSSGGNIPVVALGTWL-GHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIED 304
+++L+ G +PV+ GT+ H PK + + T A++ G+ HID+AY Y E+
Sbjct: 10 SVRLNDGPFMPVLGFGTYAPDHTPKSQAAEATK-------VAIDVGFRHIDSAYLYQNEE 62
Query: 305 QVGRALTKKFSEG-LKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWP 481
+VG+A+ +K ++G +KRE IF T KLW ++ E V PAL +SL+ L +YVDL++IH P
Sbjct: 63 EVGQAIWEKIADGTVKREEIFYTIKLWATFFRAELVHPALERSLKKLGPDYVDLFIIHVP 122
Query: 482 IAMFE-----------NDTLLDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIID 628
AM + + +L+ V+ DTW + K GL NQ
Sbjct: 123 FAMKQPGKELLPKDASGEIILETVELCDTWELELILNKPGLRYK---PTCNQ-------- 171
Query: 629 SGLEXPSALQIELNLNLQQPELFKFCRENDIVVMAYTPFGS-LFPSKAQPDAPRRGLTMN 805
+E + L Q +L +FC+ DIV++AY+ GS P PD P
Sbjct: 172 ---------VVECHPYLNQSKLLEFCKSKDIVLVAYSALGSQRDPQWVDPDCPHLLEEPI 222
Query: 806 VSSVSPXNTTNCPPVALXF 862
+ S++ ++ + VAL +
Sbjct: 223 LKSIAKKHSRSPGQVALRY 241
>UniRef50_Q9X265 Cluster: Oxidoreductase, aldo/keto reductase
family; n=2; Thermotoga|Rep: Oxidoreductase, aldo/keto
reductase family - Thermotoga maritima
Length = 274
Score = 110 bits (265), Expect = 4e-23
Identities = 68/209 (32%), Positives = 115/209 (55%), Gaps = 9/209 (4%)
Frame = +2
Query: 143 SGGNIPVVALGTW-LGHRPKGKVVQVTNDTEQAVIY--ALEAGYTHIDTAYKYG---IED 304
+G IP + LGTW +G + + D E + A++ GYTHIDTA YG E+
Sbjct: 9 TGEEIPALGLGTWGIGGF---ETPDYSRDEEMVELLKTAIKMGYTHIDTAEYYGGGHTEE 65
Query: 305 QVGRALTKKFSEGLKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPI 484
+G+A+ K F +RE +FI +K+W ++ R+ ++ +L +L+ L+ +YVDLYLIHWP
Sbjct: 66 LIGKAI-KDF----RREDLFIVSKVWPTHLRRDDLLRSLENTLKRLDTDYVDLYLIHWP- 119
Query: 485 AMFENDTLLDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGLEXPSALQIE 664
+ +T M + + GL + IG+SNF++ ++ I E Q++
Sbjct: 120 --------NPEIPLEETLSAMAEGVRQGLIRYIGVSNFDRRLLEEAISKSQEPIVCDQVK 171
Query: 665 LNLNLQQPE---LFKFCRENDIVVMAYTP 742
N+ + PE L +FC++N + ++AY+P
Sbjct: 172 YNIEDRDPERDGLLEFCQKNGVTLVAYSP 200
>UniRef50_Q05KR9 Cluster: Benzil reductase; n=5; Bacillales|Rep:
Benzil reductase - Bacillus subtilis
Length = 276
Score = 110 bits (265), Expect = 4e-23
Identities = 68/205 (33%), Positives = 105/205 (51%)
Frame = +2
Query: 128 TLQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQ 307
T++L +G +P LG + V+ N+ ++V A++ GY IDTA Y E+
Sbjct: 8 TVKLHNGVEMPWFGLGVFK--------VENGNEATESVKAAIKNGYRSIDTAAIYKNEEG 59
Query: 308 VGRALTKKFSEGLKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPIA 487
VG + + G+ RE +FIT+K+WN E + A KSLE L L+Y+DLYLIHWP
Sbjct: 60 VGIGIKES---GVAREELFITSKVWNEDQGYETTLAAFEKSLERLQLDYLDLYLIHWP-- 114
Query: 488 MFENDTLLDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGLEXPSALQIEL 667
+ DTWR + K G ++IG+SNF ++ ++ P Q+E
Sbjct: 115 --------GKDKYKDTWRALEKLYKDGKIRAIGVSNFQVHHLEELLKDAEIKPMVNQVEF 166
Query: 668 NLNLQQPELFKFCRENDIVVMAYTP 742
+ L Q EL +C+ I + A++P
Sbjct: 167 HPRLTQKELRDYCKAQGIQLEAWSP 191
>UniRef50_Q03XK0 Cluster: Aldo/keto reductase of diketogulonate
reductase family; n=3; Lactobacillales|Rep: Aldo/keto
reductase of diketogulonate reductase family -
Leuconostoc mesenteroides subsp. mesenteroides (strain
ATCC 8293 /NCDO 523)
Length = 292
Score = 110 bits (265), Expect = 4e-23
Identities = 69/204 (33%), Positives = 107/204 (52%), Gaps = 1/204 (0%)
Frame = +2
Query: 137 LSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQVGR 316
L+SG +P++ G + VQ +QAV+ A++ GY IDTA YG E +VG
Sbjct: 6 LASGIEMPLLGFGVFQ--------VQEKGAAKQAVLDAIKTGYRLIDTAASYGNEREVGE 57
Query: 317 ALTKKFSEGL-KRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPIAMF 493
A+ + ++G+ KRE +F+T+K+W +Q A++ SL+ LNL+Y+DLYLIH P
Sbjct: 58 AILEAINQGIVKREELFVTSKMWVQDVSAQQATAAIQSSLQRLNLDYLDLYLIHQPYN-- 115
Query: 494 ENDTLLDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGLEXPSALQIELNL 673
D WR M A + G K+IG+SNF+ Q+ + + P QIE+N
Sbjct: 116 ---------DVFGAWRAMESAYRSGQLKAIGVSNFDIAQLTNLAEFSDIKPMLNQIEVNP 166
Query: 674 NLQQPELFKFCRENDIVVMAYTPF 745
Q + + + + V A+ PF
Sbjct: 167 FQQNKKDITYFSQYGVQVEAWAPF 190
>UniRef50_A6WDZ5 Cluster: Aldo/keto reductase; n=5; Bacteria|Rep:
Aldo/keto reductase - Kineococcus radiotolerans SRS30216
Length = 343
Score = 110 bits (265), Expect = 4e-23
Identities = 68/231 (29%), Positives = 111/231 (48%), Gaps = 11/231 (4%)
Frame = +2
Query: 119 IVPTLQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGI 298
+VP +L G +P + +GT+ R V AV A+ AGY +D A YG
Sbjct: 12 LVPRRELRGGATVPAIGIGTFGSDRYSPAEVAA------AVAGAVAAGYRLVDCAAVYGN 65
Query: 299 EDQVGRALTKKFSEGLKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHW 478
E QVG AL + G+ R+ +F+ +K+WN H + ++ +SL +L L+++D +HW
Sbjct: 66 EAQVGEALAGAVAGGVDRDELFVVSKVWNDAHAPADAVASVHRSLRDLRLDHLDAVFVHW 125
Query: 479 PI-----AMFENDTL------LDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRII 625
P M + D D+ +L W + GL + +G SN ++ ++
Sbjct: 126 PFPNHHPPMADTDARDPRARPYDHDAYLALWGALEGLVDSGLVRHLGTSNTTVAKLDLLL 185
Query: 626 DSGLEXPSALQIELNLNLQQPELFKFCRENDIVVMAYTPFGSLFPSKAQPD 778
P+ ++EL+ QQPELF C + I + Y+P GS PS+ + D
Sbjct: 186 RDARIPPALNEMELHPCFQQPELFAHCVRHGIQPVGYSPLGS--PSRPERD 234
>UniRef50_A5ZYE6 Cluster: Putative uncharacterized protein; n=1;
Ruminococcus obeum ATCC 29174|Rep: Putative
uncharacterized protein - Ruminococcus obeum ATCC 29174
Length = 263
Score = 110 bits (265), Expect = 4e-23
Identities = 67/176 (38%), Positives = 100/176 (56%), Gaps = 3/176 (1%)
Frame = +2
Query: 224 DTEQAVIYALEAGYTHIDTAYKYGIEDQVGRALTKKFSEGLKRESIFITTKLWNSYHERE 403
+ E A+ A++ GY +DTA Y E+ VG + K G+ R+ +FITTK+WN+
Sbjct: 16 EAEDAIAAAVQNGYRLLDTASAYKNEEFVGCGIAKC---GVPRKDLFITTKIWNNAQRLG 72
Query: 404 QVIPALRKSLENLNLEYVDLYLIHWPIAMFENDTLLDNVDFLDTWRGMIDAKKLGLTKSI 583
V A ++SL+ L L+Y+DLYLIHWP+ FL+TW+ M + G SI
Sbjct: 73 DVEGAFQRSLDRLGLDYIDLYLIHWPVPGC----------FLNTWKDMEKILESGRALSI 122
Query: 584 GISNF---NQEQIQRIIDSGLEXPSALQIELNLNLQQPELFKFCRENDIVVMAYTP 742
G+SNF + E+++R+ SG+ P+ QIE + EL ++C+ NDI V AY P
Sbjct: 123 GVSNFEIRHLEELRRV--SGI-VPAVNQIECHPLCYPKELIEYCQANDIQVQAYAP 175
>UniRef50_UPI00006CCCD7 Cluster: oxidoreductase, aldo/keto reductase
family protein; n=1; Tetrahymena thermophila SB210|Rep:
oxidoreductase, aldo/keto reductase family protein -
Tetrahymena thermophila SB210
Length = 323
Score = 110 bits (264), Expect = 5e-23
Identities = 66/212 (31%), Positives = 116/212 (54%), Gaps = 6/212 (2%)
Frame = +2
Query: 131 LQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIY-ALEAGYTHIDTAYKYGIEDQ 307
+QL++G +P++ LGT +P V +VT + ++ AL+ GY + DTA +Y E +
Sbjct: 15 VQLNNGYKMPLLGLGT----QPYDIVTRVTVEEMTTLLSNALDFGYRNFDTAKQYRNEVE 70
Query: 308 VGRALTKKFSEG-LKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWP- 481
+G+A F +G KRE +FITTKL+ + +++ ++ SL+ L Y+DLYLI W
Sbjct: 71 IGQAFQNIFQQGKYKREDVFITTKLF-PFKIEKKIKEVVQNSLDQLQTSYIDLYLIQWSF 129
Query: 482 ---IAMFENDTLLDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGLEXPSA 652
+ F+ +++ + WR + + +LG+ +SIG++NFN + + ++ P
Sbjct: 130 TPVLTNFDGSVAVNHRPIHEVWRELEECVELGMIRSIGVANFNCQMVLDLLSYAKIKPVV 189
Query: 653 LQIELNLNLQQPELFKFCRENDIVVMAYTPFG 748
QIE+ L Q +L F + I +A +P G
Sbjct: 190 NQIEVTPYLPQIDLINFLKRCKIETVAISPLG 221
>UniRef50_Q3E9M9 Cluster: Uncharacterized protein At5g01670.2; n=7;
Magnoliophyta|Rep: Uncharacterized protein At5g01670.2 -
Arabidopsis thaliana (Mouse-ear cress)
Length = 349
Score = 110 bits (264), Expect = 5e-23
Identities = 80/251 (31%), Positives = 128/251 (50%), Gaps = 34/251 (13%)
Frame = +2
Query: 101 FTSADLIVPTLQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYAL-EAGYTHID 277
FTS + + +L SG IP V LGTW + + AV+ A+ E GY HID
Sbjct: 6 FTSEGQNMESFRLLSGHKIPAVGLGTW----------RSGSQAAHAVVTAIVEGGYRHID 55
Query: 278 TAYKYGIEDQVGRALTKKFSEGLK----------------RESIFITTKLWN-----SYH 394
TA++YG + +VG+ + + GL+ R+ I +++ L N +
Sbjct: 56 TAWEYGDQREVGQGIKRAMHAGLERRDLFVTSKLWYTLILRKMINLSSPLMNVLVGTCLN 115
Query: 395 ER------EQVIPALRKSLENLNLEYVDLYLIHWPIAMFENDTLLDNV-DFLD-----TW 538
+R E+V PAL+ +L+ L LEY+DLYLIHWPI + E + D LD W
Sbjct: 116 KRCTELSPERVRPALQNTLKELQLEYLDLYLIHWPIRLREGASKPPKAGDVLDFDMEGVW 175
Query: 539 RGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGLEXPSALQIELNLNLQQPELFKFCREND 718
R M + K L ++IG+ NF ++ +++ P+ Q+E++ + + +FC++N+
Sbjct: 176 REMENLSKDSLVRNIGVCNFTVTKLNKLLGFAELIPAVCQMEMHPGWRNDRILEFCKKNE 235
Query: 719 IVVMAYTPFGS 751
I V AY+P GS
Sbjct: 236 IHVTAYSPLGS 246
>UniRef50_Q8ZH36 Cluster: 2,5-diketo-D-gluconic acid reductase B;
n=91; Proteobacteria|Rep: 2,5-diketo-D-gluconic acid
reductase B - Yersinia pestis
Length = 267
Score = 110 bits (264), Expect = 5e-23
Identities = 73/196 (37%), Positives = 112/196 (57%), Gaps = 1/196 (0%)
Frame = +2
Query: 152 NIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQVGRALTKK 331
+IPV LGT+ R + ++V +V AL GY IDTA Y E VG+A+ +
Sbjct: 2 SIPVFGLGTF---RLQDQIVI------DSVSQALTLGYRAIDTAQIYENEAPVGQAIQES 52
Query: 332 FSEGLKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPIAMFENDTLL 511
G+ R+ +FITTK+W + ++++IP+LR+S++ L +YVDL LIHWP +
Sbjct: 53 ---GINRDELFITTKIWIANLSKDKLIPSLRESIQKLKTDYVDLTLIHWP-------SPN 102
Query: 512 DNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDS-GLEXPSALQIELNLNLQQP 688
D V + ++ AK LGLT+ IGISNF + +++ I + G E + QIEL+ LQ
Sbjct: 103 DEVSVAEFMSELLKAKGLGLTRQIGISNFTIDLMKQAIAAVGAEEIATNQIELSPLLQNR 162
Query: 689 ELFKFCRENDIVVMAY 736
+ F ++N I V +Y
Sbjct: 163 NVVDFAKQNGIAVTSY 178
>UniRef50_Q88TV9 Cluster: Oxidoreductase; n=4; Lactobacillus|Rep:
Oxidoreductase - Lactobacillus plantarum
Length = 288
Score = 109 bits (263), Expect = 7e-23
Identities = 73/210 (34%), Positives = 104/210 (49%), Gaps = 2/210 (0%)
Frame = +2
Query: 125 PTLQLSSGGNIPVVALGTWLGHRPKGKVVQVTND--TEQAVIYALEAGYTHIDTAYKYGI 298
PT+ L+ G IP + GT+ Q+ +D T QAV AL GY HIDTA Y
Sbjct: 5 PTITLNDGRAIPAIGFGTF----------QIPDDGSTYQAVKEALVIGYRHIDTAVAYFN 54
Query: 299 EDQVGRALTKKFSEGLKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHW 478
ED+VG+A+ G+ R+ I++T+KLW + + A+ +SL L L+Y+DLYLIH
Sbjct: 55 EDEVGQAIK---DSGIPRDQIWVTSKLWLQDYGFDAASRAIDRSLTKLRLDYIDLYLIHQ 111
Query: 479 PIAMFENDTLLDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGLEXPSALQ 658
P D W+ M A+K G KSIG+SN Q+ + P+ Q
Sbjct: 112 PYG-----------DVPGAWQAMEAAQKAGKLKSIGVSNMTPTLWQKFVPQFETIPAVNQ 160
Query: 659 IELNLNLQQPELFKFCRENDIVVMAYTPFG 748
+E N QQ L + D+ + A+ P G
Sbjct: 161 VEFNPYFQQQPLRQLLAAQDVKLEAWAPLG 190
>UniRef50_A3LWP0 Cluster: Aldo/keto reductase; n=7;
Saccharomycetales|Rep: Aldo/keto reductase - Pichia
stipitis (Yeast)
Length = 323
Score = 109 bits (263), Expect = 7e-23
Identities = 71/206 (34%), Positives = 107/206 (51%), Gaps = 10/206 (4%)
Frame = +2
Query: 179 WLGH-RPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQVGRALTKKFSEGLKRE 355
WL RP+ + +T + +++ ALE GY HIDTA Y +V A+ K G+ RE
Sbjct: 35 WLKKGRPEEEQNTLTTELVDSILLALENGYNHIDTAEVYTTHPEVAAAVKKS---GIARE 91
Query: 356 SIFITTKLWNSYHEREQVIPA----LRKSLENLNLEYVDLYLIHWPIAMFENDTLLDNVD 523
+FITTK + + + ++L+ L +YVDL+LIH P F + +
Sbjct: 92 DLFITTKYTPGFRTFPAISSGPTEFIDRALKELETDYVDLFLIHSP---FFEEKVSRGQT 148
Query: 524 FLDTWRGMIDAKKLGLTKSIGISNFNQEQIQR---IIDSGLEXPSALQIELN--LNLQQP 688
W +IDAKK G + IG+SNF++E ++R + + P QIE + L Q P
Sbjct: 149 LESAWAEVIDAKKAGKVRHIGVSNFSKEHLERTFKVAGNPDFYPKVNQIEFHPYLQNQSP 208
Query: 689 ELFKFCRENDIVVMAYTPFGSLFPSK 766
+ KF +ENDI++ AY P +LF K
Sbjct: 209 GIIKFAQENDILIEAYGPLSTLFRIK 234
>UniRef50_Q6NII7 Cluster: Putative oxidoreductase; n=2;
Corynebacterium|Rep: Putative oxidoreductase -
Corynebacterium diphtheriae
Length = 290
Score = 109 bits (262), Expect = 9e-23
Identities = 66/211 (31%), Positives = 112/211 (53%), Gaps = 1/211 (0%)
Frame = +2
Query: 119 IVPTLQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGI 298
I+PT+ L+ G +P + GT+ K+ + D +AV A+E GY HIDTA Y
Sbjct: 10 IIPTITLNDGTEMPAIGFGTY-------KLRE--QDAYRAVRSAIEVGYRHIDTASLYKN 60
Query: 299 EDQVGRALTKKFSEG-LKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIH 475
E++VGRA+ + G + R+ +FITTK+WN H + + ++SL L L+Y+D ++H
Sbjct: 61 EEEVGRAVADAITAGEVARDELFITTKVWNDMHGDQLTQRSFQESLHRLGLDYIDCCMVH 120
Query: 476 WPIAMFENDTLLDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGLEXPSAL 655
WP + L +++++ + + LG +S+ ++NF E ++ I+ P
Sbjct: 121 WP---WPQKGL-----YVESFAALAKIQGLGQLQSVAVANFYPEVLREIVAETGIAPVLN 172
Query: 656 QIELNLNLQQPELFKFCRENDIVVMAYTPFG 748
Q+EL+ Q E RE +V A++P G
Sbjct: 173 QVELHPGFSQAEQRAVDRELGVVTEAWSPLG 203
>UniRef50_Q4PHK0 Cluster: Putative uncharacterized protein; n=1;
Ustilago maydis|Rep: Putative uncharacterized protein -
Ustilago maydis (Smut fungus)
Length = 355
Score = 109 bits (262), Expect = 9e-23
Identities = 75/240 (31%), Positives = 121/240 (50%), Gaps = 32/240 (13%)
Frame = +2
Query: 128 TLQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQA----------VIYALEAGYTHI- 274
T +L++G IPV+ LGTW G+V + +A + L GY +
Sbjct: 13 TFKLNTGAEIPVIGLGTW--QSAPGEVAKAVESAIKAGYRHIVSMLTSLLTLTLGYVALH 70
Query: 275 ---------DTAYKYGIEDQVGRALTKKFSEGLKRESIFITTKLWNSYHEREQVIPALRK 427
D A+ YG E++VG+ + + G+ R +F+TTK+W +YH + + L +
Sbjct: 71 PLYIPFLAKDAAWIYGNENEVGQGIK---ASGVPRSELFVTTKIWCTYHRQPEA--CLDE 125
Query: 428 SLENLNLEYVDLYLIHWPIAMFEN-DTLL----DNVDFLD-------TWRGMIDAKKLGL 571
SL+ L L+YVDL L+HWP+ + + D + D +D TW M G
Sbjct: 126 SLQRLGLDYVDLLLVHWPVPLVKRGDEKIPLNEDGSRAIDRDWSPEQTWELMEKLPATGK 185
Query: 572 TKSIGISNFNQEQIQRIIDSGLEXPSALQIELNLNLQQPELFKFCRENDIVVMAYTPFGS 751
TK+IG+SN++ + +++ P+A Q+EL+ L Q EL K+C + I+ AY+P GS
Sbjct: 186 TKAIGVSNWSIAFLDKLLAKAKIVPAANQVELHPFLPQHELVKYCHDKGILPQAYSPLGS 245
>UniRef50_Q75E75 Cluster: ABL209Cp; n=1; Eremothecium gossypii|Rep:
ABL209Cp - Ashbya gossypii (Yeast) (Eremothecium
gossypii)
Length = 310
Score = 108 bits (260), Expect = 2e-22
Identities = 75/209 (35%), Positives = 110/209 (52%), Gaps = 6/209 (2%)
Frame = +2
Query: 134 QLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIY-ALEAGYTHIDTAYKYGIEDQV 310
+LS G IP V LG V QV+ T Q ++Y ALE GY D+A Y ED V
Sbjct: 14 RLSDGTQIPSVGLG----------VYQVSEQTVQDLVYEALEVGYRLFDSAQAYHNEDGV 63
Query: 311 GRALTK--KFSEGLKRESIFITTKLWNSYHEREQVIPALRKSLENLN-LEYVDLYLIHWP 481
R + K + G +RE ++ TTK+ H E +L KSL L Y+DL L+H P
Sbjct: 64 ARGIAAWLKHAPGRRREDVYFTTKINTQNHGYEATKKSLEKSLHAAGPLGYIDLVLVHAP 123
Query: 482 IAMFENDTLLDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIID-SGLEX-PSAL 655
++ D L TW+ + +A G +SIG+SN+ Q+ + ++ GL+ P
Sbjct: 124 MS--------DRTRRLGTWQALEEAVVEGQVRSIGVSNYGQQHLSELLGWEGLKIRPVVN 175
Query: 656 QIELNLNLQQPELFKFCRENDIVVMAYTP 742
Q+E+N L + EL ++CREN+I V A++P
Sbjct: 176 QVEINPWLCRQELVQYCRENNIAVQAFSP 204
>UniRef50_Q03U37 Cluster: Aldo/keto reductase of diketogulonate
reductase family; n=5; Lactobacillus|Rep: Aldo/keto
reductase of diketogulonate reductase family -
Lactobacillus brevis (strain ATCC 367 / JCM 1170)
Length = 282
Score = 108 bits (259), Expect = 2e-22
Identities = 72/210 (34%), Positives = 108/210 (51%)
Frame = +2
Query: 119 IVPTLQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGI 298
I T +L+ G +PV+ GT+L + Q T +T A+ A +AGY DTA Y
Sbjct: 6 ITATRKLADGRQMPVMGFGTYLLND------QPTMNT--AIQTAWDAGYRMFDTAMLYRN 57
Query: 299 EDQVGRALTKKFSEGLKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHW 478
ED +G A+ + GL RE +F+T+K+ +Q + A+ SL+ L +Y+DL LIHW
Sbjct: 58 EDILGPAIQQL---GLPREGLFLTSKVAEIVQGYDQTMKAVEGSLKRLQTDYLDLLLIHW 114
Query: 479 PIAMFENDTLLDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGLEXPSALQ 658
P+ F DTWR + K G KSIG+SN+ ++ + E P Q
Sbjct: 115 PV----------REHFFDTWRALEQLKADGQVKSIGVSNYTIAHLELLATKAKEMPVVNQ 164
Query: 659 IELNLNLQQPELFKFCRENDIVVMAYTPFG 748
+E + L Q L + +E+DIV A++P G
Sbjct: 165 VEYHPYLNQQALADYDQEHDIVTEAWSPLG 194
>UniRef50_Q7R2T6 Cluster: GLP_291_56367_57278; n=1; Giardia lamblia
ATCC 50803|Rep: GLP_291_56367_57278 - Giardia lamblia
ATCC 50803
Length = 303
Score = 108 bits (259), Expect = 2e-22
Identities = 61/187 (32%), Positives = 94/187 (50%), Gaps = 15/187 (8%)
Frame = +2
Query: 233 QAVIYALEAGYTHIDTAYKYGIEDQVGRALTKKFSE---GLKRESIFITTKLWNSYHERE 403
+A+ A++ GY H D AY+YG E +G + F++ G+KRE ++I +KLW ++HE E
Sbjct: 19 EAIRSAVKLGYRHFDCAYRYGNERMIGEVFKEIFNDDSYGVKREDLWIVSKLWPNFHEPE 78
Query: 404 QVIPALRKSLENLNLEYVDLYLIHWPIA---MFEND---------TLLDNVDFLDTWRGM 547
+V + ++L +L LEY+D++L+HWP+A + + D TLL TW M
Sbjct: 79 KVAYQISETLRDLQLEYLDVFLMHWPLAIKHLADRDYASSDGKGGTLLGTTPIRKTWEAM 138
Query: 548 IDAKKLGLTKSIGISNFNQEQIQRIIDSGLEXPSALQIELNLNLQQPELFKFCRENDIVV 727
T+ IG+SN + ++ P Q E L +FC N I V
Sbjct: 139 EACVDKKQTRFIGVSNMGTAMLVDLLSYCRIKPFTNQFESQPYFPNDRLIEFCNSNGIYV 198
Query: 728 MAYTPFG 748
AY P G
Sbjct: 199 TAYRPLG 205
>UniRef50_A3JU52 Cluster: 2,5-diketo-D-gluconic acid reductase A;
n=1; Rhodobacterales bacterium HTCC2150|Rep:
2,5-diketo-D-gluconic acid reductase A - Rhodobacterales
bacterium HTCC2150
Length = 334
Score = 107 bits (258), Expect = 3e-22
Identities = 73/213 (34%), Positives = 111/213 (52%), Gaps = 9/213 (4%)
Frame = +2
Query: 128 TLQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYA-LEAGYTHIDTAYKYGIED 304
T L++ IP V GT+L ++ND ++ I A ++AGY HIDTA Y E
Sbjct: 39 TFTLNTTTTIPAVGFGTYL----------ISNDDAKSTISAAIQAGYRHIDTASGYQNEK 88
Query: 305 QVGRALTKKF-SEGLKRESIFITTKLW-------NSYHEREQVIPALRKSLENLNLEYVD 460
VG + S G+ R+ +F+T KLW ++ + Q + SL L L+YVD
Sbjct: 89 TVGAGIKAGLQSAGITRKDLFVTAKLWPGNPAWGDAPKTKAQTLDECDASLARLGLDYVD 148
Query: 461 LYLIHWPIAMFENDTLLDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGLE 640
LYLIH P + D L+ WR +++ + G +SIG+SNFN+ + I +GL
Sbjct: 149 LYLIHAP---YGGDMRLEQ------WRALLELQANGKARSIGVSNFNESHLNEIKAAGLP 199
Query: 641 XPSALQIELNLNLQQPELFKFCRENDIVVMAYT 739
P A QIEL+ Q+P+L + ++ I +AY+
Sbjct: 200 MPDANQIELHPWSQKPDLLAYMDQHAIAPIAYS 232
>UniRef50_A0JX62 Cluster: 2,5-didehydrogluconate reductase; n=9;
Bacteria|Rep: 2,5-didehydrogluconate reductase -
Arthrobacter sp. (strain FB24)
Length = 291
Score = 107 bits (256), Expect = 5e-22
Identities = 67/189 (35%), Positives = 97/189 (51%), Gaps = 14/189 (7%)
Frame = +2
Query: 224 DTEQAVIYALEAGYTHIDTAYKYGIEDQVGRAL--------------TKKFSEGLKRESI 361
D V ALEAGY H DTA YG E VG+A+ + + + L RE +
Sbjct: 29 DAAGLVTMALEAGYRHFDTAAMYGNETGVGKAIGALAGFAGGGPAGGSGEAAPSLSREDL 88
Query: 362 FITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPIAMFENDTLLDNVDFLDTWR 541
F+TTK+WN H + + A S+ NL +EYVDLYLIHWP A F +++R
Sbjct: 89 FVTTKVWNDDHGYDATMRAFDTSMSNLGMEYVDLYLIHWPCAR--------RGLFTESYR 140
Query: 542 GMIDAKKLGLTKSIGISNFNQEQIQRIIDSGLEXPSALQIELNLNLQQPELFKFCRENDI 721
M + G ++IG+SNF ++ ++++ P+ QIEL+ LQQ EL + I
Sbjct: 141 AMETLYREGRIRAIGVSNFQPAHLEHLLETAEVVPAVNQIELHPWLQQDELRQLHDRLGI 200
Query: 722 VVMAYTPFG 748
A++P G
Sbjct: 201 RTEAWSPLG 209
>UniRef50_Q5FT75 Cluster: Putative 2,5-diketo-D-gluconic acid
reductase; n=1; Gluconobacter oxydans|Rep: Putative
2,5-diketo-D-gluconic acid reductase - Gluconobacter
oxydans (Gluconobacter suboxydans)
Length = 279
Score = 106 bits (255), Expect = 7e-22
Identities = 65/206 (31%), Positives = 102/206 (49%)
Frame = +2
Query: 131 LQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQV 310
+ G +P + LG W P + +V + A++ GY +DTA Y E+ V
Sbjct: 14 ISFHDGHTMPQIGLGVW--ETPPDETAEVVKE-------AVKLGYRSVDTARLYKNEEGV 64
Query: 311 GRALTKKFSEGLKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPIAM 490
G+ L IF+TTKLWN + + A +S L +DLYLIHWP+
Sbjct: 65 GKGLED-------HPEIFLTTKLWNDEQGYDSTLRAYEESARLLRRPVLDLYLIHWPMPA 117
Query: 491 FENDTLLDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGLEXPSALQIELN 670
+++TW+ +++ KK G KSIG+SNF E ++RI+D+ P QIEL+
Sbjct: 118 --------QGQYVETWKALVELKKSGRVKSIGVSNFESEHLERIMDATGVVPVVNQIELH 169
Query: 671 LNLQQPELFKFCRENDIVVMAYTPFG 748
+ QQ L +F +++I ++ P G
Sbjct: 170 PDFQQRALREFHEKHNIRTESWRPLG 195
>UniRef50_Q89JN4 Cluster: Oxidoreductase; n=8; Rhizobiales|Rep:
Oxidoreductase - Bradyrhizobium japonicum
Length = 272
Score = 106 bits (254), Expect = 9e-22
Identities = 64/202 (31%), Positives = 108/202 (53%), Gaps = 1/202 (0%)
Frame = +2
Query: 140 SSGGNIPVVALGTW-LGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQVGR 316
++G IP + LGTW L RP +VV+ AL GY HIDTA Y E +VG
Sbjct: 6 ANGARIPAIGLGTWELSGRPCARVVE----------QALRLGYRHIDTAQVYDNEREVGD 55
Query: 317 ALTKKFSEGLKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPIAMFE 496
+ + G++R+ +F+TTK+W ++ + ++++SL L L VDL L+HWP +
Sbjct: 56 GVR---ASGVRRDDVFLTTKVWTNHFAPNDLERSVKESLARLRLPSVDLLLLHWPNS--- 109
Query: 497 NDTLLDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGLEXPSALQIELNLN 676
+V +T + A+++GLT+ IG+SNF I++ + E Q+E +
Sbjct: 110 ------HVPLAETLGALSHARQMGLTRHIGVSNFTVALIEQAVALSPEPLVCNQVEFHPY 163
Query: 677 LQQPELFKFCRENDIVVMAYTP 742
L Q ++ C ++ + ++AY+P
Sbjct: 164 LDQAKVRAACDQHGLALVAYSP 185
>UniRef50_A0L1A2 Cluster: Aldo/keto reductase; n=8;
Gammaproteobacteria|Rep: Aldo/keto reductase -
Shewanella sp. (strain ANA-3)
Length = 280
Score = 105 bits (252), Expect = 2e-21
Identities = 65/176 (36%), Positives = 96/176 (54%), Gaps = 1/176 (0%)
Frame = +2
Query: 221 NDTEQAVIYALEAGYTHIDTAYKYGIEDQVGRALTKKFSEGLKRESIFITTKLWNSYHER 400
N AV+ ALE G HIDTA YG E VG A+ + G+ RE +FITTK+W +
Sbjct: 30 NAAFDAVLMALEEGSRHIDTAQIYGNEQAVGDAIN---TSGIPREELFITTKVWTENLTK 86
Query: 401 EQVIPALRKSLENLNLEYVDLYLIHWPIAMFENDTLLDNVDFLDTWRGMIDAKKLGLTKS 580
E+ ++ SL L +Y+DL LIHWP+ N V++L + ++D GLT+
Sbjct: 87 ERFETSVIDSLTALQTKYLDLLLIHWPL----NSDEPSMVEYLSELKAVLDK---GLTRR 139
Query: 581 IGISNFNQEQI-QRIIDSGLEXPSALQIELNLNLQQPELFKFCRENDIVVMAYTPF 745
IG+SNF Q+ Q I G Q+E++ L ++ FCR+++++V Y PF
Sbjct: 140 IGVSNFTNAQLAQAIAILGEGVIYTNQVEVHPYLINRKVTDFCRQHNVLVTGYMPF 195
>UniRef50_Q17DN1 Cluster: Aldo-keto reductase; n=1; Aedes
aegypti|Rep: Aldo-keto reductase - Aedes aegypti
(Yellowfever mosquito)
Length = 284
Score = 105 bits (252), Expect = 2e-21
Identities = 74/220 (33%), Positives = 112/220 (50%), Gaps = 2/220 (0%)
Frame = +2
Query: 125 PTLQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIED 304
P ++L++G +PV+ LGTWL +G +A+ A++AGY HIDTAY Y E
Sbjct: 6 PMVKLNNGLEMPVLGLGTWLSKEGEGV---------EAIKAAIDAGYRHIDTAYFYQNEK 56
Query: 305 QVGRALTKKFSEGLK-RESIFITTKLWNSYHEREQVIP-ALRKSLENLNLEYVDLYLIHW 478
+VG A+ K EG+ RE +F+TTK + + + ++P L+ +++Y+D
Sbjct: 57 EVGEAIRAKIEEGVVCREDLFVTTKFID--WDTKNLMPYDADGKLQFSDVDYID------ 108
Query: 479 PIAMFENDTLLDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGLEXPSALQ 658
TW+ M K G KSIG+SNFN EQI R++ P Q
Sbjct: 109 ------------------TWKAMEKLLKTGKVKSIGVSNFNSEQITRLLAECEIKPVTNQ 150
Query: 659 IELNLNLQQPELFKFCRENDIVVMAYTPFGSLFPSKAQPD 778
+E N +L Q +L +FC+ DI + AY+P G + PD
Sbjct: 151 VECNPSLNQRKLTEFCKNLDITLTAYSPLGRPNYYEKDPD 190
>UniRef50_Q6F7K7 Cluster: 2,5-diketo-D-gluconate reductase; n=20;
Bacteria|Rep: 2,5-diketo-D-gluconate reductase -
Acinetobacter sp. (strain ADP1)
Length = 297
Score = 105 bits (251), Expect = 2e-21
Identities = 67/209 (32%), Positives = 107/209 (51%)
Frame = +2
Query: 122 VPTLQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIE 301
+P L L G +IP + GT+ +G DT ++ AL GY +D+A+ Y E
Sbjct: 22 IPDLILHDGHSIPALGFGTYTLKGQQGV------DT---MLRALGHGYRMLDSAFNYENE 72
Query: 302 DQVGRALTKKFSEGLKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWP 481
VG A+ + GL R+ IFIT+KL +H ++ + + +SL + +Y+DLYLIHWP
Sbjct: 73 GAVGAAVRQS---GLLRDEIFITSKLPGRHHAYDKAMETIEESLYRMQFDYLDLYLIHWP 129
Query: 482 IAMFENDTLLDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGLEXPSALQI 661
+++ W+ +IDA+K G +SIG+SNF + I+ + P Q+
Sbjct: 130 NP--------QQGLYIEAWQALIDAQKKGYIRSIGVSNFLPKHIETLRRETGVIPVINQV 181
Query: 662 ELNLNLQQPELFKFCRENDIVVMAYTPFG 748
EL+ Q E + I+ MA++P G
Sbjct: 182 ELHPYFNQAEQRAYDESQQIITMAWSPLG 210
>UniRef50_Q0CK00 Cluster: Predicted protein; n=1; Aspergillus
terreus NIH2624|Rep: Predicted protein - Aspergillus
terreus (strain NIH 2624)
Length = 292
Score = 105 bits (251), Expect = 2e-21
Identities = 72/222 (32%), Positives = 109/222 (49%), Gaps = 2/222 (0%)
Frame = +2
Query: 125 PTLQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIED 304
P L L G +P++ GT + + + ALE G+ HID A YG E
Sbjct: 4 PALSLKDGNLVPILGFGTGTAWYKDDPNDPTNPELIEVLKAALEKGFHHIDAADSYGTER 63
Query: 305 QVGRALTKKFSEGLKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPI 484
+VG A+ + G+ RE +FITTK+ + + V AL SLE L L+YVDLYL+H P
Sbjct: 64 EVGIAIRES---GIPREQLFITTKVLEGWKD---VPGALDASLERLQLDYVDLYLLHNPY 117
Query: 485 AMFENDTLLDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGLEXPSALQIE 664
+ N T D W+G+ K G +SIG+SNF + ++ I+++ P+ Q+E
Sbjct: 118 VI-PNLT-----DIQSAWKGLEAVKATGKARSIGVSNFQRNHLEAILETCSVVPAINQLE 171
Query: 665 LNLNLQQP-ELFKFCRENDIVVMAYTPFGSLFPSKAQP-DAP 784
+ LQ+ + + RE I V ++ + K P D P
Sbjct: 172 YHPYLQRSHDFIPWMRERGIEVSSFKTLAPVTVGKGGPLDEP 213
>UniRef50_Q927P9 Cluster: Lin2739 protein; n=12; Bacteria|Rep:
Lin2739 protein - Listeria innocua
Length = 283
Score = 104 bits (250), Expect = 3e-21
Identities = 66/206 (32%), Positives = 105/206 (50%)
Frame = +2
Query: 128 TLQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQ 307
T++L++G +P++ GT+ + + EQAV A+ AGY HIDTA Y E+
Sbjct: 3 TVKLNNGIEVPILGFGTYQ--------ITDAGEAEQAVKEAIAAGYRHIDTAQSYMNEEA 54
Query: 308 VGRALTKKFSEGLKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPIA 487
VGR + + G+ R+ +FITTK+W + V+ + +SL+ L L+Y+DL LIH P
Sbjct: 55 VGRGIA---ASGVDRKELFITTKIWVENVSYKGVMSSFDRSLKRLGLDYIDLLLIHQPYN 111
Query: 488 MFENDTLLDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGLEXPSALQIEL 667
D W M + + G K+IG+SNF +++ + P QIE+
Sbjct: 112 -----------DVYGAWMAMEELQAQGKIKAIGVSNFGVDRVVDLAAFNDITPQVNQIEI 160
Query: 668 NLNLQQPELFKFCRENDIVVMAYTPF 745
N QQ + + R+ + V A+ PF
Sbjct: 161 NPFQQQSKNIEALRKEGVAVEAWAPF 186
>UniRef50_A3VRL4 Cluster: Putative uncharacterized protein; n=1;
Parvularcula bermudensis HTCC2503|Rep: Putative
uncharacterized protein - Parvularcula bermudensis
HTCC2503
Length = 278
Score = 103 bits (248), Expect = 5e-21
Identities = 66/198 (33%), Positives = 104/198 (52%)
Frame = +2
Query: 155 IPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQVGRALTKKF 334
IP + GTW + +G+ + + T A+E GY HID A Y E +VG +
Sbjct: 11 IPRLGFGTW---QLEGEDARTSTRT------AIETGYRHIDGAAIYKNEKKVGEGIK--- 58
Query: 335 SEGLKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPIAMFENDTLLD 514
G+ R+ +F+TTK+WN ++ + A+ +SL+ L L+YV+L L+HWPI ND
Sbjct: 59 DSGIPRDELFVTTKIWNEDIQKGRHSEAVDESLDRLGLDYVNLILLHWPI----ND---- 110
Query: 515 NVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGLEXPSALQIELNLNLQQPEL 694
+ D + + K+ G K IGISN+NQ Q + + E +A+Q E + L Q +
Sbjct: 111 -MPIADQVGPLAEIKRSGRAKLIGISNYNQAQFLEAVSASEEPLAAIQCEYHPMLDQDPI 169
Query: 695 FKFCRENDIVVMAYTPFG 748
K R D++ +Y+P G
Sbjct: 170 LKTARGFDMMFTSYSPLG 187
>UniRef50_O13848 Cluster: NADH/NADPH dependent indole-3-acetaldehyde
reductase AKR3C2; n=1; Schizosaccharomyces pombe|Rep:
NADH/NADPH dependent indole-3-acetaldehyde reductase
AKR3C2 - Schizosaccharomyces pombe (Fission yeast)
Length = 284
Score = 103 bits (247), Expect = 6e-21
Identities = 67/211 (31%), Positives = 105/211 (49%), Gaps = 2/211 (0%)
Frame = +2
Query: 155 IPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQVGRALTKKF 334
+P +GT L + KG++ + D+ V AL AG+ HID A YG E++VG AL +
Sbjct: 12 VPAYGVGTALFKKEKGEINRTIVDS---VKNALAAGFIHIDCAEVYGNEEEVGVALKEA- 67
Query: 335 SEGLKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPIAMFENDTLLD 514
+ R +FIT+K+ H + + AL +SL L +Y+DLYL+H PI +E
Sbjct: 68 --NVPRSKLFITSKVM---HNVDNIPEALNESLRKLGTDYLDLYLLHSPIPFYEK----- 117
Query: 515 NVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGLEXPSALQIELNLNLQQ--P 688
+ + W+ M A GL S+G+SNF ++ ++ + P QIE + + +
Sbjct: 118 KIPISEGWKAMETALGTGLVHSVGVSNFRIPDLEELLKTSTITPRVNQIEFHPQVYKAAK 177
Query: 689 ELFKFCRENDIVVMAYTPFGSLFPSKAQPDA 781
L +FC+ I+V Y P L P A
Sbjct: 178 PLVEFCQSKGIIVEGYGPLSPLVRDAQGPVA 208
>UniRef50_Q4V008 Cluster: Oxidoreductase; n=4; Proteobacteria|Rep:
Oxidoreductase - Xanthomonas campestris pv. campestris
(strain 8004)
Length = 267
Score = 103 bits (246), Expect = 8e-21
Identities = 72/195 (36%), Positives = 103/195 (52%), Gaps = 1/195 (0%)
Frame = +2
Query: 155 IPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQVGRALTKKF 334
+P LGT+ R K +VV +V AL GY IDTA Y E QVG+A+
Sbjct: 3 VPAFGLGTF---RLKDQVVI------DSVRNALALGYRAIDTAQIYDNEAQVGQAIA--- 50
Query: 335 SEGLKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPIAMFENDTLLD 514
G+ R+ +F+TTK+W R+ + P+L++SL L +YVDL LIHWP + D
Sbjct: 51 DAGVPRDQLFVTTKIWVDRFSRDTLQPSLQESLRKLGTDYVDLTLIHWP-------SPKD 103
Query: 515 NVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIID-SGLEXPSALQIELNLNLQQPE 691
V + + DAK GLT++IG+SNF ++ I+ G + + QIE++ LQ
Sbjct: 104 QVPMREYLEALADAKAQGLTRAIGVSNFTIALTRQAIEILGADAIATNQIEVHPYLQNRT 163
Query: 692 LFKFCRENDIVVMAY 736
L F RE I V +Y
Sbjct: 164 LIAFLREQGIHVTSY 178
>UniRef50_Q0SFM4 Cluster: Probable 2,5-didehydrogluconate reductase;
n=1; Rhodococcus sp. RHA1|Rep: Probable
2,5-didehydrogluconate reductase - Rhodococcus sp.
(strain RHA1)
Length = 265
Score = 103 bits (246), Expect = 8e-21
Identities = 64/199 (32%), Positives = 106/199 (53%)
Frame = +2
Query: 152 NIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQVGRALTKK 331
+IP + LGTW P D +AV+ +EAGY IDTA Y ED VG AL +
Sbjct: 3 DIPPLGLGTWPLTGP---------DATRAVLSGIEAGYRLIDTATIYDNEDAVGVALAEC 53
Query: 332 FSEGLKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPIAMFENDTLL 511
G+ RE +F+TTKL S H + A+ +SL+NL L+ +DL+LIHWP+
Sbjct: 54 ---GVPREELFVTTKLRGSDHVSGDIRGAVERSLKNLGLDRLDLFLIHWPLPRHNR---- 106
Query: 512 DNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGLEXPSALQIELNLNLQQPE 691
++ + M+ + GL + +G+SNF + ++R++ E P+ QI+++ +L +
Sbjct: 107 ----YVAAFEAMLACRDAGLVRHVGVSNFLETHLRRVVAETGESPAVNQIQMDPSLARLP 162
Query: 692 LFKFCRENDIVVMAYTPFG 748
+ + E + +++P G
Sbjct: 163 VRRADDELGVSTQSWSPLG 181
>UniRef50_Q5XJM7 Cluster: Zgc:101765; n=5; Eumetazoa|Rep: Zgc:101765
- Danio rerio (Zebrafish) (Brachydanio rerio)
Length = 288
Score = 102 bits (244), Expect = 1e-20
Identities = 70/211 (33%), Positives = 109/211 (51%), Gaps = 2/211 (0%)
Frame = +2
Query: 125 PTLQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIED 304
P++ L++ +P++ LGT+ R +G+ DT AV AL+AGY DTA Y E
Sbjct: 6 PSVLLNNDIQMPLLGLGTF---RLQGQ-----EDTYSAVDAALKAGYRAFDTAAVYRNEA 57
Query: 305 QVGRALTKKFSE-GLKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWP 481
+G AL + GL RE +FIT+KL + + +KSLE L L Y+DLYLIHWP
Sbjct: 58 HLGHALRCLLPKHGLSREDVFITSKL-GPKDQGSKARNGCQKSLEQLGLGYIDLYLIHWP 116
Query: 482 IAM-FENDTLLDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGLEXPSALQ 658
+ + +WR + + G ++IG+SN+ E +Q ++ S P+ LQ
Sbjct: 117 GTQGLPVGDKRNPENRAQSWRVLEEFYSEGKFRAIGVSNYTVEHMQELLKSCKVPPAVLQ 176
Query: 659 IELNLNLQQPELFKFCRENDIVVMAYTPFGS 751
+E + L Q +L C+ + AY+ G+
Sbjct: 177 VEFHPKLLQNDLRGLCKIRGVCFQAYSSLGT 207
>UniRef50_Q929C8 Cluster: Lin2349 protein; n=12; Listeria|Rep:
Lin2349 protein - Listeria innocua
Length = 294
Score = 102 bits (244), Expect = 1e-20
Identities = 60/169 (35%), Positives = 91/169 (53%)
Frame = +2
Query: 236 AVIYALEAGYTHIDTAYKYGIEDQVGRALTKKFSEGLKRESIFITTKLWNSYHEREQVIP 415
AV A+E GY DTA Y E VG+A+ + RE +FI++K+WN ++ +
Sbjct: 36 AVEKAIEVGYRLFDTAAVYNNEAIVGQAI---LDSAVPREELFISSKVWNGDLGYDETLF 92
Query: 416 ALRKSLENLNLEYVDLYLIHWPIAMFENDTLLDNVDFLDTWRGMIDAKKLGLTKSIGISN 595
A ++L NL L+Y+DLYLIHWP+A + D+WR M L KSIG++N
Sbjct: 93 AFERTLRNLKLDYLDLYLIHWPVA----------GKYRDSWRAMERLHDEKLIKSIGVAN 142
Query: 596 FNQEQIQRIIDSGLEXPSALQIELNLNLQQPELFKFCRENDIVVMAYTP 742
F Q + ++ + E P Q+E + L Q +L K+ E +I A++P
Sbjct: 143 FKQHHLSDLLVAANEKPVLNQVETHPLLPQNDLRKYLAEQNIAHAAWSP 191
>UniRef50_A7SGW6 Cluster: Predicted protein; n=1; Nematostella
vectensis|Rep: Predicted protein - Nematostella
vectensis
Length = 264
Score = 102 bits (244), Expect = 1e-20
Identities = 59/179 (32%), Positives = 97/179 (54%)
Frame = +2
Query: 206 VVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQVGRALTKKFSEGLKRESIFITTKLWN 385
V ++ E ++AL+ GY +DTA Y E +VG A+ K GLKRE I++TTKL
Sbjct: 28 VFRLETGCEDVCLFALKNGYRMLDTADIYQNEKEVGSAVRKS---GLKREDIYVTTKLKP 84
Query: 386 SYHEREQVIPALRKSLENLNLEYVDLYLIHWPIAMFENDTLLDNVDFLDTWRGMIDAKKL 565
S + ++S++ L++ YVDL+LIH P N+ + + ++ K+
Sbjct: 85 SEEGHSNALKYAKESIKKLDIGYVDLFLIHTPRP--------GNI--IAAYDALLTLKEE 134
Query: 566 GLTKSIGISNFNQEQIQRIIDSGLEXPSALQIELNLNLQQPELFKFCRENDIVVMAYTP 742
GL +S+G+SNF ++ + +G P+ QIE+N +Q E+ K+C ++ I V Y P
Sbjct: 135 GLIRSVGVSNFGVHHLEELRKAGCRTPAINQIEINPFWRQEEIIKYCNKHGITVEGYAP 193
>UniRef50_Q8Y463 Cluster: Lmo2592 protein; n=40; Bacteria|Rep:
Lmo2592 protein - Listeria monocytogenes
Length = 283
Score = 101 bits (243), Expect = 2e-20
Identities = 66/208 (31%), Positives = 107/208 (51%), Gaps = 2/208 (0%)
Frame = +2
Query: 128 TLQLSSGGNIPVVALGTWLGHRPKGKVVQVTN--DTEQAVIYALEAGYTHIDTAYKYGIE 301
T++L++G +P++ GT+ Q+T+ + E AV A++AGY HIDTA Y E
Sbjct: 3 TVKLNNGVEVPILGFGTY----------QITDAAEAEHAVKDAIKAGYRHIDTAQSYMNE 52
Query: 302 DQVGRALTKKFSEGLKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWP 481
+ VGR + + G+ R+ +FITTK+W + V+ + +SL+ L L+YVDL LIH P
Sbjct: 53 EAVGRGIA---ASGVDRKELFITTKIWVENVSYKGVMSSFDRSLKRLGLDYVDLLLIHQP 109
Query: 482 IAMFENDTLLDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGLEXPSALQI 661
D W M + + G ++IG+SNF+ +++ + P QI
Sbjct: 110 FN-----------DVYGAWIAMEELQASGKIRAIGVSNFSPDRVIDLAAFNEVTPQVNQI 158
Query: 662 ELNLNLQQPELFKFCRENDIVVMAYTPF 745
E+N QQ R+ + + A+ PF
Sbjct: 159 EVNPFQQQTANLAILRKEGVAIEAWAPF 186
>UniRef50_Q1M4Z6 Cluster: Putative aldo-keto reductase/oxidase; n=1;
Rhizobium leguminosarum bv. viciae 3841|Rep: Putative
aldo-keto reductase/oxidase - Rhizobium leguminosarum
bv. viciae (strain 3841)
Length = 274
Score = 101 bits (243), Expect = 2e-20
Identities = 65/177 (36%), Positives = 97/177 (54%), Gaps = 3/177 (1%)
Frame = +2
Query: 221 NDTEQAVIYALEAGYTHIDTAYKYGIEDQVGRALTKKFSEGLKRESIFITTKLWNSYHER 400
++ Q VI+ALEAG HIDTA YG E V R + G+ R IFITTK+ +
Sbjct: 23 DEAHQGVIWALEAGCRHIDTAQGYGNEQDVARGIK---DAGVARNEIFITTKVKPDNYGP 79
Query: 401 EQVIPALRKSLENLNLEYVDLYLIHWPIAMFENDTLLDNVDFLDTWRGMIDAKKLGLTKS 580
V+P++R+SLE L ++ VDL L+HWP N L D+L + + D+ GL +
Sbjct: 80 GAVMPSVRESLEKLRVDQVDLLLLHWPSP--HNKYPL--ADYLGQFAEVFDS---GLARQ 132
Query: 581 IGISNFNQEQIQ---RIIDSGLEXPSALQIELNLNLQQPELFKFCRENDIVVMAYTP 742
IG+SNF + I R++DS + Q+E ++ +Q + +C+ I V AY+P
Sbjct: 133 IGVSNFTKAMIDESIRLLDS--RTITTNQVECHVYMQNRPIIDYCQNLGIAVTAYSP 187
>UniRef50_A2QB88 Cluster: Contig An01c0460, complete genome.
precursor; n=1; Aspergillus niger|Rep: Contig An01c0460,
complete genome. precursor - Aspergillus niger
Length = 351
Score = 101 bits (243), Expect = 2e-20
Identities = 80/230 (34%), Positives = 114/230 (49%), Gaps = 20/230 (8%)
Frame = +2
Query: 158 PVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQVGRALTKKFS 337
P V LGT+ G V ++AV+ AL GY HIDTA YG E +VG A+ +
Sbjct: 47 PAVGLGTFQGDAGNRGV-------KEAVLQALRCGYRHIDTATAYGNEIEVGEAIKES-- 97
Query: 338 EGLKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEY---VDLY------LIHWPIAM 490
+ RE I +TTKL ++H V AL SLE L L Y + LY + H
Sbjct: 98 -RIPREEIIVTTKLAQTWHRVSDVERALDLSLERLQLNYGLSMHLYSASSYSVPHAYSPG 156
Query: 491 FENDTL--------LDNV---DFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGL 637
+N+T+ +D+ D+ TW M G K IG+SNFN +++R++ S
Sbjct: 157 PDNNTIRHPNGKPIIDHELSRDYPSTWAAMESLVDKGKLKMIGVSNFNILKLERLLGSAR 216
Query: 638 EXPSALQIELNLNLQQPELFKFCRENDIVVMAYTPFGSLFPSKAQPDAPR 787
P+ QIEL+ L Q EL +FC+ N I ++A+ P G + P+A R
Sbjct: 217 IPPAVNQIELHPYLPQVELVRFCKANGIHLVAHQPLGGKPVAAVNPNADR 266
>UniRef50_Q5UX52 Cluster: Oxidoreductase aldo/keto reductase family;
n=1; Haloarcula marismortui|Rep: Oxidoreductase
aldo/keto reductase family - Haloarcula marismortui
(Halobacterium marismortui)
Length = 274
Score = 101 bits (243), Expect = 2e-20
Identities = 67/200 (33%), Positives = 102/200 (51%), Gaps = 1/200 (0%)
Frame = +2
Query: 146 GGNIPVVALGTWLGHRPKGKVVQVTNDT-EQAVIYALEAGYTHIDTAYKYGIEDQVGRAL 322
G ++P + LGTW Q+T + + V AL GY HIDTA YG E QVG +
Sbjct: 8 GTSVPALGLGTW----------QLTGQSCRETVETALGMGYRHIDTAQAYGNERQVGLGM 57
Query: 323 TKKFSEGLKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPIAMFEND 502
+ + RE +F+TTKL S + V + R+SL L +Y+DL LIHWP N
Sbjct: 58 D---AAAVDREDVFLTTKLDGSNRDERSVRRSTRESLNKLGTDYLDLLLIHWP-----NT 109
Query: 503 TLLDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGLEXPSALQIELNLNLQ 682
+ ++ +T M D + GL + IG+SNF+ + R D Q++ +
Sbjct: 110 PWMASLS--ETLGAMNDVVEEGLVRHIGVSNFSPSLLDRARDISSAPIFTDQVQYHPYWD 167
Query: 683 QPELFKFCRENDIVVMAYTP 742
Q +L +CR +D+++ AY+P
Sbjct: 168 QRKLLDYCRIHDVLLTAYSP 187
>UniRef50_Q927E1 Cluster: Lin2848 protein; n=13; Listeria|Rep:
Lin2848 protein - Listeria innocua
Length = 280
Score = 101 bits (241), Expect = 3e-20
Identities = 58/167 (34%), Positives = 87/167 (52%)
Frame = +2
Query: 248 ALEAGYTHIDTAYKYGIEDQVGRALTKKFSEGLKRESIFITTKLWNSYHEREQVIPALRK 427
A++ GY DTA Y E ++G S GLKR+ F+TTK+WN+ ++ + A K
Sbjct: 40 AVDVGYRLFDTASFYHNEKELGDFFA---SSGLKRDEFFVTTKMWNTEQGYDETLRAFEK 96
Query: 428 SLENLNLEYVDLYLIHWPIAMFENDTLLDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQE 607
S + L L+ VDLYL+HWP + DT F +TWR + GL ++IG+SNF
Sbjct: 97 SQKKLQLDQVDLYLVHWP----KQDT------FFETWRAVEKLYDEGLVRAIGVSNFEAH 146
Query: 608 QIQRIIDSGLEXPSALQIELNLNLQQPELFKFCRENDIVVMAYTPFG 748
+ R+ S P Q+E + + L ++ E IV A++P G
Sbjct: 147 HLDRLRTSANVLPVVDQLETHPHFPNQLLHRYLEELHIVHQAWSPLG 193
>UniRef50_Q7XY49 Cluster: Mannose 6-phosphate reductase; n=1;
Griffithsia japonica|Rep: Mannose 6-phosphate reductase
- Griffithsia japonica (Red alga)
Length = 174
Score = 90.6 bits (215), Expect(2) = 3e-20
Identities = 50/116 (43%), Positives = 71/116 (61%), Gaps = 1/116 (0%)
Frame = +2
Query: 128 TLQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQ 307
T L SG +P+ GTW K V +TEQAV AL AGY HID A Y E
Sbjct: 5 TATLQSGAKMPLNGFGTW-----KASV----EETEQAVTAALRAGYRHIDCAAVYWNEAA 55
Query: 308 VGRALTKKFSEGL-KRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLI 472
VG A++K S G+ KRE +FIT+K+WN+ H ++V+ + R+SL++ ++Y DL+L+
Sbjct: 56 VGTAISKAISGGVVKREDLFITSKVWNTCHATDKVVDSCRQSLKDHQVDYFDLFLV 111
Score = 31.1 bits (67), Expect(2) = 3e-20
Identities = 16/55 (29%), Positives = 28/55 (50%)
Frame = +2
Query: 548 IDAKKLGLTKSIGISNFNQEQIQRIIDSGLEXPSALQIELNLNLQQPELFKFCRE 712
+D L L + IG+SN++ + ++ PS Q E ++ +P+L CRE
Sbjct: 103 VDYFDLFLVRDIGVSNYSVALLVDTLNYARIKPSVNQCEAHVYFARPQLRDVCRE 157
>UniRef50_A7TLC4 Cluster: Putative uncharacterized protein; n=1;
Vanderwaltozyma polyspora DSM 70294|Rep: Putative
uncharacterized protein - Vanderwaltozyma polyspora DSM
70294
Length = 313
Score = 100 bits (239), Expect = 6e-20
Identities = 73/212 (34%), Positives = 105/212 (49%), Gaps = 6/212 (2%)
Frame = +2
Query: 137 LSSGGNIP---VVALGTWLGHRPKGKVVQVTNDTEQAVIYALEA-GYTHIDTAYKYGIED 304
L++G IP ++ GT RP G +++ + + YAL G HID A YG
Sbjct: 10 LNNGNQIPSISIIGTGTRWFKRP-GSEHTFSDELVEQIKYALSLPGIIHIDAAECYGTYP 68
Query: 305 QVGRALTKKFSEGLKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPI 484
++ +AL K+ S+ R IFIT K I L L+ L L+YVDLYLIH P
Sbjct: 69 ELAKAL-KESSK--PRSEIFITDKYSTQTKFTNDPIEGLNTGLKTLGLDYVDLYLIHSP- 124
Query: 485 AMFENDTLLDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGLEXPSALQIE 664
F + ++ W+ M K G KSIG+SNF+ + I+ I+ P QIE
Sbjct: 125 --FFDPEFKGSLTLEKVWKDMETLYKEGKAKSIGVSNFSVKNIEEILKIAGIKPQVNQIE 182
Query: 665 LN--LNLQQPELFKFCRENDIVVMAYTPFGSL 754
N L Q P + +C++N+I + AY+P G L
Sbjct: 183 FNAFLQNQTPGIVNYCQKNNIQLEAYSPLGPL 214
>UniRef50_Q02198 Cluster: Morphine 6-dehydrogenase; n=5;
Bacteria|Rep: Morphine 6-dehydrogenase - Pseudomonas
putida
Length = 296
Score = 100 bits (239), Expect = 6e-20
Identities = 66/208 (31%), Positives = 104/208 (50%)
Frame = +2
Query: 125 PTLQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIED 304
P + L++G +P + LG + +T A+ A+ +GY IDTA Y E
Sbjct: 6 PLINLNNGVKMPALGLGVFAAS---------AEETASAIASAISSGYRLIDTARSYNNEA 56
Query: 305 QVGRALTKKFSEGLKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPI 484
QVG + + G+ R +F+TTKL+N + E+ + A +SL L L+YVDLYL+HWP
Sbjct: 57 QVGEGIR---NSGVDRAEMFVTTKLFNCDYGYERALRAFDESLGRLGLDYVDLYLLHWPT 113
Query: 485 AMFENDTLLDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGLEXPSALQIE 664
+ N T + +W+ G ++IG+ NF ++Q+ +I + P+ QIE
Sbjct: 114 KDW-NAT-------IQSWKAAEKILGDGRARAIGVCNFLEDQLDELIAASDVVPAVNQIE 165
Query: 665 LNLNLQQPELFKFCRENDIVVMAYTPFG 748
L+ Q L R IV A++P G
Sbjct: 166 LHPYFAQKPLLAKNRALGIVTEAWSPIG 193
>UniRef50_Q5FK99 Cluster: Oxidoreductase aldo-keto reductase family;
n=5; Lactobacillus|Rep: Oxidoreductase aldo-keto
reductase family - Lactobacillus acidophilus
Length = 289
Score = 99 bits (238), Expect = 8e-20
Identities = 68/210 (32%), Positives = 105/210 (50%), Gaps = 2/210 (0%)
Frame = +2
Query: 122 VPTLQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTE--QAVIYALEAGYTHIDTAYKYG 295
+P ++L+ G IP + G V Q++N E +AV A+ GY IDTA Y
Sbjct: 4 IPKIKLNDGNEIPQLGFG----------VFQISNHDEAVKAVESAISNGYRLIDTAEAYN 53
Query: 296 IEDQVGRALTKKFSEGLKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIH 475
+ VG A+ + + R+ IF+TTKLW S E+ A+ + L+ L +Y+D+ L+H
Sbjct: 54 NQTAVGEAIK---NSDVNRDDIFLTTKLWVSNFTYEKASKAIDEDLKELGTDYIDMMLLH 110
Query: 476 WPIAMFENDTLLDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGLEXPSAL 655
D WR + DA+K G TKSIG+SNF +Q+ + P
Sbjct: 111 QAYG-----------DVAGAWRALEDAQKAGKTKSIGVSNFWPDQLMNLQLMSNVKPVVN 159
Query: 656 QIELNLNLQQPELFKFCRENDIVVMAYTPF 745
QIE+N Q+ K+ +++D+ V A+ PF
Sbjct: 160 QIEVNPWFQREPEVKWNQKDDVAVEAWAPF 189
>UniRef50_Q1RFP0 Cluster: 2,5-diketo-D-gluconic acid reductase A;
n=21; Bacteria|Rep: 2,5-diketo-D-gluconic acid reductase
A - Escherichia coli (strain UTI89 / UPEC)
Length = 294
Score = 99 bits (238), Expect = 8e-20
Identities = 65/185 (35%), Positives = 94/185 (50%), Gaps = 4/185 (2%)
Frame = +2
Query: 206 VVQVTNDT--EQAVIYALEAGYTHIDTAYKYGIEDQVGRALTKKFSEGL-KRESIFITTK 376
V QVT+ +Q+V+ A+ GY IDTA YG ED VG A+ + SEGL RE +FIT+K
Sbjct: 24 VFQVTDKDVCKQSVLNAIRTGYRLIDTAAVYGNEDAVGEAVREAISEGLCTREELFITSK 83
Query: 377 LWNSYHEREQVIPA-LRKSLENLNLEYVDLYLIHWPIAMFENDTLLDNVDFLDTWRGMID 553
LW + + A + SL+ LEY DLYL+H + D+ WR + D
Sbjct: 84 LWVQDMLNQDIAAAGIEASLKKSGLEYFDLYLLHQAMR-----------DYFSAWRALED 132
Query: 554 AKKLGLTKSIGISNFNQEQIQRIIDSGLEXPSALQIELNLNLQQPELFKFCRENDIVVMA 733
A + G K+IG+SNF + ++ P Q+EL+ QPE + ++ A
Sbjct: 133 AYEEGKLKAIGVSNFYPHVLANFCETVRVKPMVNQVELHPYFAQPEALATMKYYNVQPEA 192
Query: 734 YTPFG 748
+ P G
Sbjct: 193 WAPLG 197
>UniRef50_UPI0000D56CE5 Cluster: PREDICTED: similar to CG6084-PA,
isoform A; n=1; Tribolium castaneum|Rep: PREDICTED:
similar to CG6084-PA, isoform A - Tribolium castaneum
Length = 493
Score = 99.5 bits (237), Expect = 1e-19
Identities = 54/120 (45%), Positives = 74/120 (61%), Gaps = 11/120 (9%)
Frame = +2
Query: 425 KSLENLNLEYVDLYLIHWPIAMFENDTL--LD---------NVDFLDTWRGMIDAKKLGL 571
+SL+NL L+Y+D+YL+HWP A+ E +L +D +VDF+DTW+ M + L
Sbjct: 271 ESLKNLQLDYLDVYLMHWPHALKEGPSLHPIDPKTGLFIPSDVDFVDTWKAMEKMHEKDL 330
Query: 572 TKSIGISNFNQEQIQRIIDSGLEXPSALQIELNLNLQQPELFKFCRENDIVVMAYTPFGS 751
TKSIGISNFN QI R++ S P QIE + L Q +L KFC + I V +Y+P GS
Sbjct: 331 TKSIGISNFNSNQIDRLLKSAKIAPVINQIECHPYLNQSKLRKFCSDRGITVTSYSPLGS 390
Score = 81.8 bits (193), Expect = 2e-14
Identities = 50/152 (32%), Positives = 85/152 (55%), Gaps = 1/152 (0%)
Frame = +2
Query: 299 EDQVGRALTKKFSEG-LKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIH 475
E + G AL + G ++R+ +F+ +K + + V AL +L+ L + Y+DLYLI
Sbjct: 55 EKRFGVALQQLIEGGKIRRKDLFLMSKFCCT-NTTNLVKAALLDTLKKLQVAYLDLYLIE 113
Query: 476 WPIAMFENDTLLDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGLEXPSAL 655
P A +++ ++TW M LT++IG+SNFN +QI+RI+++ P
Sbjct: 114 RPPACKDHN-------LIETWEAMEGLYSEKLTRAIGLSNFNSKQIERILENCTIRPQVN 166
Query: 656 QIELNLNLQQPELFKFCRENDIVVMAYTPFGS 751
QI+ + L Q +L K+C N I V++Y+P G+
Sbjct: 167 QIQCHPYLNQAKLRKYCSNNGIAVISYSPLGA 198
>UniRef50_UPI00006CA3CB Cluster: oxidoreductase, aldo/keto reductase
family protein; n=3; Tetrahymena thermophila SB210|Rep:
oxidoreductase, aldo/keto reductase family protein -
Tetrahymena thermophila SB210
Length = 299
Score = 99.5 bits (237), Expect = 1e-19
Identities = 69/214 (32%), Positives = 107/214 (50%), Gaps = 2/214 (0%)
Frame = +2
Query: 107 SADLIVPTLQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAY 286
S+ I + LS+G +P LG+ VQ + + AL+ GY HIDTA
Sbjct: 2 SSQEIQKVITLSNGQKMPAFGLGS--------SRVQSVEEVTNLIRKALDVGYRHIDTAQ 53
Query: 287 KYGIEDQVGRALTKKFSEG-LKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDL 463
Y E +G AL F EG KRE IF+ TK + + + +++ L+ L ++YVDL
Sbjct: 54 MYENEQFIGAALKTIFGEGKYKREDIFLVTK--QASIKGVSCLEIMKEQLQKLQVDYVDL 111
Query: 464 YLIHWPIAMFEND-TLLDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGLE 640
LIH P+A +D ++ W + LGL K +G+SNFN + I ++
Sbjct: 112 LLIHVPLAAPSDDYQQWNHKPVHQIWAEFEEIHSLGLAKGLGVSNFNCQMIIDLLAYCKI 171
Query: 641 XPSALQIELNLNLQQPELFKFCRENDIVVMAYTP 742
P QIEL++ QQ L +F ++ +I +A++P
Sbjct: 172 KPLVNQIELHVFNQQKNLVEFLKKVNIYPVAFSP 205
>UniRef50_P70883 Cluster: AkrI; n=1; Butyrivibrio fibrisolvens|Rep:
AkrI - Butyrivibrio fibrisolvens
Length = 172
Score = 99.5 bits (237), Expect = 1e-19
Identities = 57/167 (34%), Positives = 90/167 (53%), Gaps = 1/167 (0%)
Frame = +2
Query: 131 LQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQV 310
++L++G IP+ GT+ ++ N+ +V AL+ GY HIDTA Y E V
Sbjct: 8 IKLNNGTAIPMFGYGTYK--------IKDQNEAYNSVRLALKNGYRHIDTAAFYENEKFV 59
Query: 311 GRALTKKFSEG-LKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPIA 487
A+ E KRE IF+T+K W + ++ + A K++ + ++Y+DLYL+HWP A
Sbjct: 60 ANAIKDFMEESQTKREDIFVTSKAWKTELGYDKTLAAFEKTMNEMQMDYLDLYLVHWP-A 118
Query: 488 MFENDTLLDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIID 628
+ D +N + TW+ M + K G K+IG+SNF + IID
Sbjct: 119 SYAFDDDWENTN-RQTWKAMTEIYKSGRVKAIGVSNFLTHHLDTIID 164
>UniRef50_A3VHZ9 Cluster: Oxidoreductase; n=1; Rhodobacterales
bacterium HTCC2654|Rep: Oxidoreductase - Rhodobacterales
bacterium HTCC2654
Length = 278
Score = 99.5 bits (237), Expect = 1e-19
Identities = 66/221 (29%), Positives = 105/221 (47%)
Frame = +2
Query: 125 PTLQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIED 304
PT+ L++G +P + LGTW ++ +AV A+E GY IDTA Y E
Sbjct: 8 PTVTLANGVEMPQLGLGTW---------PMTDDEAAKAVATAIETGYRLIDTAENYKNET 58
Query: 305 QVGRALTKKFSEGLKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPI 484
VG+ + G+ R+ +F+TTK+ +H + A SLE L L+Y+DL+LIHWP
Sbjct: 59 GVGQGIR---DAGVARDEVFLTTKMNKQWHSVDGARRACEASLERLGLDYIDLFLIHWPN 115
Query: 485 AMFENDTLLDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGLEXPSALQIE 664
D +++ + G+ GL ++IG SNF + + +G P QI+
Sbjct: 116 P--------DQGTYVEAFEGLTRLLDAGLVRAIGTSNFLPHHLNDLFAAGF-VPHVNQIQ 166
Query: 665 LNLNLQQPELFKFCRENDIVVMAYTPFGSLFPSKAQPDAPR 787
L+ +P++ IV +++P G A P R
Sbjct: 167 LDPYHLRPDITAIHAAKGIVTESWSPIGRAGEMLADPAITR 207
>UniRef50_A2RMU6 Cluster: Oxidoreductase, aldo/keto reductase
family; n=3; Lactococcus lactis|Rep: Oxidoreductase,
aldo/keto reductase family - Lactococcus lactis subsp.
cremoris (strain MG1363)
Length = 281
Score = 99.5 bits (237), Expect = 1e-19
Identities = 72/204 (35%), Positives = 104/204 (50%)
Frame = +2
Query: 137 LSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQVGR 316
L+ G IP LG + P+G+ TE AV AL GY HIDTA+ Y E VGR
Sbjct: 7 LNDGNIIPQFGLGVY--QIPEGEA------TENAVKEALRLGYRHIDTAHAYQNERSVGR 58
Query: 317 ALTKKFSEGLKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPIAMFE 496
A+ S G+ I+IT+KLW S + + A+ + LE LNL+ +DL L+H + +
Sbjct: 59 AI---HSSGIPISEIWITSKLWPS--DYDDASQAIERMLELLNLKQIDLLLLHQQVGNYR 113
Query: 497 NDTLLDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGLEXPSALQIELNLN 676
W + +A K G KSIGISNF+ E++ + + PSALQ+E +
Sbjct: 114 K-----------AWIALENAVKSGKVKSIGISNFDGERLVDLFNFADIKPSALQVETHPY 162
Query: 677 LQQPELFKFCRENDIVVMAYTPFG 748
QQ EL +F + + ++ P G
Sbjct: 163 HQQKELQEFLKPYGTKIESWYPLG 186
>UniRef50_A7BES9 Cluster: Putative uncharacterized protein; n=1;
Actinomyces odontolyticus ATCC 17982|Rep: Putative
uncharacterized protein - Actinomyces odontolyticus ATCC
17982
Length = 282
Score = 99.1 bits (236), Expect = 1e-19
Identities = 70/206 (33%), Positives = 106/206 (51%)
Frame = +2
Query: 131 LQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQV 310
+ L++G IP V LGT+L +D + AV YAL+ YT IDTA Y E V
Sbjct: 4 ITLNNGITIPQVGLGTYLLE---------PDDAQSAVTYALDNDYTLIDTANVYVNERAV 54
Query: 311 GRALTKKFSEGLKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPIAM 490
GR + + R+ IF+ TKLW S+ ER A+ ++LE L +Y+DL ++H P
Sbjct: 55 GRGMR---ASSKARDEIFLETKLWPSFFERAS---AVEETLERLGTDYIDLMILHQPAG- 107
Query: 491 FENDTLLDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGLEXPSALQIELN 670
D + +R + A K G ++IG+SNF+ Q QRI+D P+ Q+E +
Sbjct: 108 ----------DTVAGYRILEKAHKEGKIRAIGLSNFDVAQTQRILDECEVVPTINQVECH 157
Query: 671 LNLQQPELFKFCRENDIVVMAYTPFG 748
Q EL ++++I + A+ P G
Sbjct: 158 PYFPQTELKALLKDHNITLQAWYPLG 183
>UniRef50_A6LZ55 Cluster: 2,5-didehydrogluconate reductase; n=1;
Clostridium beijerinckii NCIMB 8052|Rep:
2,5-didehydrogluconate reductase - Clostridium
beijerinckii NCIMB 8052
Length = 289
Score = 99.1 bits (236), Expect = 1e-19
Identities = 67/212 (31%), Positives = 107/212 (50%)
Frame = +2
Query: 113 DLIVPTLQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKY 292
+LI ++ +G IP V G + + KG+ D E AV A++ GY H DTA Y
Sbjct: 2 NLINKEIKAVNGIKIPQVGFGVYKLN--KGE------DFETAVGEAIKIGYRHFDTAKIY 53
Query: 293 GIEDQVGRALTKKFSEGLKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLI 472
G E +G A+ K + RE FIT+K+WN+ H E A ++ + LN+EY+D+YLI
Sbjct: 54 GNEKDLGLAIEKS---QIPREEFFITSKVWNTDHGYEATKKAFEQTCKKLNVEYLDMYLI 110
Query: 473 HWPIAMFENDTLLDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGLEXPSA 652
H+ + +L+TW M + G K IG++NF + ++ ++ P
Sbjct: 111 HFASSY-----------YLETWHAMEELYLQGKIKVIGVANFQIQHLEELMKHSRITPMI 159
Query: 653 LQIELNLNLQQPELFKFCRENDIVVMAYTPFG 748
QIE + Q EL ++ ++ I+ A+ P G
Sbjct: 160 NQIETHPEFPQNELHQYLTKHKILHEAWAPLG 191
>UniRef50_Q11B35 Cluster: Aldo/keto reductase; n=1; Mesorhizobium
sp. BNC1|Rep: Aldo/keto reductase - Mesorhizobium sp.
(strain BNC1)
Length = 253
Score = 98.7 bits (235), Expect = 2e-19
Identities = 64/196 (32%), Positives = 102/196 (52%)
Frame = +2
Query: 155 IPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQVGRALTKKF 334
+P++ LGTW Q+T++T + V A + GY +DT+ YG + +G A+
Sbjct: 1 MPILGLGTW----------QLTHETARTVRAAFDLGYRMVDTSGDYGTQSAIGEAIR--- 47
Query: 335 SEGLKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPIAMFENDTLLD 514
+ GL R+ I++ TK+ E E A + +L L L+Y DL LIH P + L
Sbjct: 48 ASGLDRDDIYLVTKV----EETEDAYNATQANLRELGLDYADLILIHRPPRHGAGEEL-- 101
Query: 515 NVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGLEXPSALQIELNLNLQQPEL 694
WR +I A++ GLT+ IG+SN++ E I+ ++D+ E P Q+E + EL
Sbjct: 102 -------WRALIRAREDGLTRDIGVSNYSIELIEELVDATGEIPVVNQVEWSPFGHDLEL 154
Query: 695 FKFCRENDIVVMAYTP 742
+ N IV+ AY+P
Sbjct: 155 KHYADFNGIVIQAYSP 170
>UniRef50_Q1DLF1 Cluster: Putative uncharacterized protein; n=1;
Coccidioides immitis|Rep: Putative uncharacterized
protein - Coccidioides immitis
Length = 324
Score = 98.7 bits (235), Expect = 2e-19
Identities = 61/183 (33%), Positives = 96/183 (52%), Gaps = 10/183 (5%)
Frame = +2
Query: 230 EQAVIYALEAGYTHIDTAYKYG---IEDQVGRALTKKFSEGLKRESIFITTKLWNSYHER 400
+ +V++AL+ GY HID A YG +E +G A+ + G+ RE +F+ TKL N +H
Sbjct: 37 KDSVLHALKIGYRHIDAALAYGWGSVERGIGAAIR---ASGVPREDVFVVTKLHNCFHAP 93
Query: 401 EQVIPALRKSLENLNLEYVDLYLI----HWPIAMFENDTLLD---NVDFLDTWRGMIDAK 559
E V + SL+NL L YV + + + ++D + F TW+ M +
Sbjct: 94 EDVEVGMNMSLKNLGLGYVPYAYTKGENYSTVRKPDGKPVVDIELSRAFDTTWKAMENLV 153
Query: 560 KLGLTKSIGISNFNQEQIQRIIDSGLEXPSALQIELNLNLQQPELFKFCRENDIVVMAYT 739
G K IG+SNF+ +++R++ P Q+ELN Q +L +FC E++I V AY
Sbjct: 154 DQGKAKLIGVSNFSTPKLKRLLSVCRIFPVVNQVELNPYFPQKQLLRFCHEHEIHVTAYG 213
Query: 740 PFG 748
P G
Sbjct: 214 PLG 216
>UniRef50_A3UJS6 Cluster: Oxidoreductase; n=3;
Alphaproteobacteria|Rep: Oxidoreductase - Oceanicaulis
alexandrii HTCC2633
Length = 275
Score = 97.9 bits (233), Expect = 3e-19
Identities = 62/201 (30%), Positives = 95/201 (47%)
Frame = +2
Query: 140 SSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQVGRA 319
++G +IP + GTW D + V AL+ GY HIDTA YG E VG
Sbjct: 7 ANGADIPKLGFGTWQLE---------DEDAARGVATALKTGYRHIDTAQIYGNEAAVGDG 57
Query: 320 LTKKFSEGLKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPIAMFEN 499
+ G+KRE F+TTK+W + ++++SL+ L +YVDL L+HWP+
Sbjct: 58 WKQS---GVKREDFFLTTKVWRDKFRDGDLQASVKESLDKLKTDYVDLLLLHWPV----- 109
Query: 500 DTLLDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGLEXPSALQIELNLNL 679
V +T + M + K+ G + IG+SNF + + A Q+E + L
Sbjct: 110 ----PEVPIAETMKAMNEVKEAGQVRHIGVSNFTVDLLDEARAHSGAPLVANQVEYHPYL 165
Query: 680 QQPELFKFCRENDIVVMAYTP 742
Q + CR + + AY+P
Sbjct: 166 DQNAVLTACRAAGMAMTAYSP 186
>UniRef50_Q9HM42 Cluster: Alcohol dehydrogenase related protein;
n=1; Thermoplasma acidophilum|Rep: Alcohol dehydrogenase
related protein - Thermoplasma acidophilum
Length = 284
Score = 97.9 bits (233), Expect = 3e-19
Identities = 64/211 (30%), Positives = 111/211 (52%), Gaps = 6/211 (2%)
Frame = +2
Query: 143 SGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQVGRAL 322
+G + V+ +GTW + + V+ ++ YAL+ G IDTA YG ED VG A+
Sbjct: 12 TGRKVSVIGVGTWSLEGSRSENVR-------SIRYALDHGVNFIDTAEMYGTEDIVGEAI 64
Query: 323 TKKFSEGLKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPIAMFEND 502
+G +RE +FI TK+W ++ V+ + +SL+ L +YVDLY +HWP
Sbjct: 65 -----KGYRREDLFIATKVWPTHFAYHDVLKSCEESLKKLGTDYVDLYQLHWP------- 112
Query: 503 TLLDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGLEXP-SALQIELNLNL 679
+V +T M G + IGISNF+ ++++ + + + + Q+E N+
Sbjct: 113 --NPSVSIKETMSAMEKLVDEGRIRYIGISNFSVKEMKEAMSALAKYRIVSNQLEYNVAT 170
Query: 680 QQPE---LFKFCRENDIVVMAYTPF--GSLF 757
++ E ++ FCR+N + ++AY+P G +F
Sbjct: 171 REIEDEGIYDFCRKNGMAIIAYSPLSHGKIF 201
>UniRef50_A7D6Q0 Cluster: Aldo/keto reductase; n=1; Halorubrum
lacusprofundi ATCC 49239|Rep: Aldo/keto reductase -
Halorubrum lacusprofundi ATCC 49239
Length = 309
Score = 97.9 bits (233), Expect = 3e-19
Identities = 67/208 (32%), Positives = 104/208 (50%), Gaps = 1/208 (0%)
Frame = +2
Query: 122 VPTLQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIE 301
+PT L SG +P + LGT+ + +V AL +GYTHIDTA Y E
Sbjct: 34 IPTQTLPSGDTLPALGLGTY---------ALDDDQIADSVRAALSSGYTHIDTAEGYHNE 84
Query: 302 DQVGRALTKKFSEGLKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWP 481
+ +G L + R+ +F+T+K+ E +I + SLE L +Y+DLYLIHWP
Sbjct: 85 EAIGEVLAE-----YDRDDVFLTSKVLAKNLGYESLIQSCEASLERLETDYLDLYLIHWP 139
Query: 482 IAMFENDTLLDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGLEXPSAL-Q 658
N + ++ + M + GL +++G+SNF+ Q+ + E P A+ Q
Sbjct: 140 -----NPA----ISLRESLQAMAELHDRGLVRNVGVSNFSAYQLS-CANHISEVPIAVNQ 189
Query: 659 IELNLNLQQPELFKFCRENDIVVMAYTP 742
IE + Q+P L +C E+D V+ A P
Sbjct: 190 IEFHPWFQRPNLVDYCHESDTVIEAAAP 217
>UniRef50_Q54NR2 Cluster: Aldo-keto reductase; n=3; Dictyostelium
discoideum AX4|Rep: Aldo-keto reductase - Dictyostelium
discoideum AX4
Length = 305
Score = 97.5 bits (232), Expect = 4e-19
Identities = 58/183 (31%), Positives = 97/183 (53%), Gaps = 11/183 (6%)
Frame = +2
Query: 221 NDTEQAVIYALEAGYTHIDTAYKYGIEDQVGRALTKKFSEG-------LKRESIFITTKL 379
ND E + LE GY IDTA Y E+++G+ L + ++ +KRE +FIT+K
Sbjct: 38 NDIENIIKVGLENGYRRIDTASMYNNEERIGKVLNEMVTKNDGLDGKKIKREDLFITSKC 97
Query: 380 WNSYHEREQVIPALRKSLENLNLEYVDLYLIHWP-IAMFENDTLLDNVDFLDTWRGMIDA 556
E + A SL+ L L+Y+D YLIHWP + + +++ TWR +
Sbjct: 98 SFMEQGYENALKAFESSLKKLQLDYLDCYLIHWPGVKGLDGSDSGNSIQRAQTWRALEKL 157
Query: 557 KKLGLTKSIGISNFNQEQIQRIIDS-GLE-XPSALQIELN-LNLQQPELFKFCRENDIVV 727
+ +SIG+SN+ + ++ S L+ P+ Q+E + LN Q+ +L +FC+ N I++
Sbjct: 158 YQDKKVRSIGVSNYTINHLTELLSSPNLQIKPAINQVEFHPLNFQK-DLLEFCKNNKIIL 216
Query: 728 MAY 736
+Y
Sbjct: 217 ESY 219
>UniRef50_A7P424 Cluster: Chromosome chr1 scaffold_5, whole genome
shotgun sequence; n=1; Vitis vinifera|Rep: Chromosome
chr1 scaffold_5, whole genome shotgun sequence - Vitis
vinifera (Grape)
Length = 247
Score = 97.1 bits (231), Expect = 5e-19
Identities = 56/156 (35%), Positives = 88/156 (56%), Gaps = 11/156 (7%)
Frame = +2
Query: 236 AVIYALEAGYTHIDTAYKYGIEDQVGRALTKKFSEGL--KRESIFITTKLWNSYHEREQV 409
+++ A+E GY H D Y E +G A+ K GL R+ +FIT+KLW S ++V
Sbjct: 37 SILTAIELGYRHFDCVAAYLSEKPLGEAIKKAVKLGLIKSRDELFITSKLWCSDAHHDRV 96
Query: 410 IPALRKSLE---------NLNLEYVDLYLIHWPIAMFENDTLLDNVDFLDTWRGMIDAKK 562
+PAL+ +L+ NL L+Y+DLYLIHW +D L +D W+ M D +K
Sbjct: 97 LPALQNTLKISSILSFSKNLQLDYLDLYLIHW------SDGHLP-IDLGSVWKAMEDFQK 149
Query: 563 LGLTKSIGISNFNQEQIQRIIDSGLEXPSALQIELN 670
L LTK+IG+SNF+ +++ ++ + P+ Q+ N
Sbjct: 150 LSLTKAIGVSNFSCNKLEELLQTASILPAVNQVSEN 185
>UniRef50_Q76L36 Cluster: Conjugated polyketone reductase C2; n=1;
Candida parapsilosis|Rep: Conjugated polyketone
reductase C2 - Candida parapsilosis (Yeast)
Length = 307
Score = 97.1 bits (231), Expect = 5e-19
Identities = 68/226 (30%), Positives = 110/226 (48%), Gaps = 9/226 (3%)
Frame = +2
Query: 104 TSADLIVPTLQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTA 283
T ++L+ T + SG I + ALGT + + V+ + ++ L+ G+ HIDTA
Sbjct: 2 TQSNLLPKTFRTKSGKEISI-ALGTGTKWKQAQTINDVSTELVDNILLGLKLGFRHIDTA 60
Query: 284 YKYGIEDQVGRALTKKFSEGLKRESIFITTKL---WNSYHE-REQVIPALRKSLENLNLE 451
Y + +VG AL + + RE I++TTK W S + ++ K+L L ++
Sbjct: 61 EAYNTQKEVGEALKR---TDVPREDIWVTTKYSPGWGSIKAYSKSPSDSIDKALAQLGVD 117
Query: 452 YVDLYLIHWPIAMFENDTLLDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRII-- 625
YVDL+LIH P E W +++AKK G + IGISN ++++
Sbjct: 118 YVDLFLIHSPFFTTEQ---THGYTLEQAWEALVEAKKAGKVREIGISNAAIPHLEKLFAA 174
Query: 626 -DSGLEXPSALQIELN--LNLQQPELFKFCRENDIVVMAYTPFGSL 754
S P QIE + L Q + +FC+E+ I+V A++P L
Sbjct: 175 SPSPEYYPVVNQIEFHPFLQNQSKNIVRFCQEHGILVEAFSPLAPL 220
>UniRef50_Q5V398 Cluster: Oxidoreductase aldo/keto reductase family;
n=1; Haloarcula marismortui|Rep: Oxidoreductase
aldo/keto reductase family - Haloarcula marismortui
(Halobacterium marismortui)
Length = 302
Score = 97.1 bits (231), Expect = 5e-19
Identities = 65/173 (37%), Positives = 98/173 (56%), Gaps = 4/173 (2%)
Frame = +2
Query: 236 AVIYALEAGYTHIDTAYKYGIEDQVGRALTKKFSEGLKRESIFITTKL--WNSYHEREQV 409
AV AL+ GYTHIDTA Y E VGRA+ + + RE IF+TTK+ + E E++
Sbjct: 38 AVKNALDCGYTHIDTAMAYENEAAVGRAIEQS---SVDREDIFLTTKIKGYPEMVEYERL 94
Query: 410 IPALRKSLENLNLEYVDLYLIHW--PIAMFENDTLLDNVDFLDTWRGMIDAKKLGLTKSI 583
I A + LE L EY+DL L+HW P+A E + + L+T ++D GL I
Sbjct: 95 IEAAKGCLERLGTEYLDLLLVHWWNPLADME-----ETFNALNT---LVDD---GLVGQI 143
Query: 584 GISNFNQEQIQRIIDSGLEXPSALQIELNLNLQQPELFKFCRENDIVVMAYTP 742
G+SNF+ +++++ + + QIE + EL +FC++ND+ V AY+P
Sbjct: 144 GVSNFSIKELKQAMRLSDAPIATNQIEYHPYWGDEELVRFCQDNDVTVTAYSP 196
>UniRef50_Q14LA8 Cluster: Putative aldo/keto reductase
oxidoreductase protein; n=1; Spiroplasma citri|Rep:
Putative aldo/keto reductase oxidoreductase protein -
Spiroplasma citri
Length = 263
Score = 96.7 bits (230), Expect = 7e-19
Identities = 61/175 (34%), Positives = 95/175 (54%), Gaps = 1/175 (0%)
Frame = +2
Query: 230 EQAVIYALEAGYTHIDTAYKYGIEDQVGRALTKKF-SEGLKRESIFITTKLWNSYHEREQ 406
E+A+I AL+ GY IDTA Y E+ VGRA+ K S +RE I I TK+W E
Sbjct: 18 EEAIINALQNGYKIIDTAKVYQNEEIVGRAIKKYLNSNNQRREDIIIETKIWCDDVEAGN 77
Query: 407 VIPALRKSLENLNLEYVDLYLIHWPIAMFENDTLLDNVDFLDTWRGMIDAKKLGLTKSIG 586
A+ +SL+ LN+ Y+D+ LIH P F T+ V+ L K GL +G
Sbjct: 78 TTNAVLESLKRLNVTYLDIVLIHRPNLNFYK-TIKAYVELLQ-------CKAKGLINVVG 129
Query: 587 ISNFNQEQIQRIIDSGLEXPSALQIELNLNLQQPELFKFCRENDIVVMAYTPFGS 751
+SNF+++ I+ + + P+ QIE N Q+ + ++C+ +I+V +Y+P +
Sbjct: 130 VSNFDKDMIEILFEETGAYPNLNQIEFNPFNQRWDRVQYCQNKNILVQSYSPIAN 184
>UniRef50_Q03BE0 Cluster: Aldo/keto reductase family enzyme; n=5;
Lactobacillus|Rep: Aldo/keto reductase family enzyme -
Lactobacillus casei (strain ATCC 334)
Length = 281
Score = 96.7 bits (230), Expect = 7e-19
Identities = 61/205 (29%), Positives = 108/205 (52%), Gaps = 3/205 (1%)
Frame = +2
Query: 146 GGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQVGRALT 325
G N+P++ +GTW + +G Q + A+ Y L G T IDTA YG + +L
Sbjct: 8 GVNVPIMGMGTW--YLGEGNAAQSEQEAA-ALKYGLNHGLTVIDTAEMYG--NGAAESLI 62
Query: 326 KKFSEGLKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPIAMFENDT 505
F R +I++ +K + S+ ++ Q++ AL+ SL+ L +Y+DLYL+HW
Sbjct: 63 GSFLGDYDRANIYLISKFYPSHADKRQMLTALKNSLKRLQTDYLDLYLLHW--------- 113
Query: 506 LLDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRI-IDSGLEXPSALQIELNLNLQ 682
+ +T G+ D +K GL K G+SNF+ + + ++ ++ G + +A ++ NL +
Sbjct: 114 -RGSTPLAETLEGLQDLQKEGLIKQYGVSNFDVDDMDQLTLEPGGDQIAANEVLYNLQSR 172
Query: 683 QPE--LFKFCRENDIVVMAYTPFGS 751
E L ++ +I + Y+PFGS
Sbjct: 173 SIEYDLLPQQKQANITTIGYSPFGS 197
>UniRef50_A7ALH6 Cluster: Putative uncharacterized protein; n=1;
Parabacteroides merdae ATCC 43184|Rep: Putative
uncharacterized protein - Parabacteroides merdae ATCC
43184
Length = 301
Score = 96.7 bits (230), Expect = 7e-19
Identities = 63/209 (30%), Positives = 105/209 (50%)
Frame = +2
Query: 122 VPTLQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIE 301
VPT++L++G +P + +GT+L V ++ + V +A++ G+ IDTA YG E
Sbjct: 29 VPTVKLNNGMEMPQLGVGTFL----------VKDNAAERVCHAIKVGFRLIDTAQGYGNE 78
Query: 302 DQVGRALTKKFSEGLKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWP 481
+VG + + G+ R +FITTK+ V +L KSL +L +Y+DL LIHWP
Sbjct: 79 KEVGEGICRS---GIDRRELFITTKVNTMEMRGGTVRQSLDKSLADLGTDYIDLVLIHWP 135
Query: 482 IAMFENDTLLDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGLEXPSALQI 661
+ +TW+ + + G +SIG+SNFN + +++ P QI
Sbjct: 136 V----------KGHIKETWQILEEYVDKGKIRSIGVSNFNPHHLDELLEYARIRPVVNQI 185
Query: 662 ELNLNLQQPELFKFCRENDIVVMAYTPFG 748
E+ + Q ++ + I V A+ P G
Sbjct: 186 EIEPYMTQHDVVGYTFRKGIQVEAWGPLG 214
>UniRef50_A6PR52 Cluster: Aldo/keto reductase; n=1; Victivallis
vadensis ATCC BAA-548|Rep: Aldo/keto reductase -
Victivallis vadensis ATCC BAA-548
Length = 287
Score = 96.7 bits (230), Expect = 7e-19
Identities = 71/220 (32%), Positives = 110/220 (50%), Gaps = 9/220 (4%)
Frame = +2
Query: 122 VPTLQLSSGGNIPVVALGTWLGHRPKG-KVVQVTNDTEQ--AVIYALEAGYTHIDTAYKY 292
VP L +G IPV+ GTW R G ND A+ + G HIDTA Y
Sbjct: 4 VPWKSLKNGFAIPVLGQGTW---RMGGVDTPDTANDDADIAAIRRGIATGLCHIDTAEMY 60
Query: 293 G---IEDQVGRALTKKFSEGLKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDL 463
E+ VG A+ +G++R F+T K+W ++ + V+ A SL+ L +Y+DL
Sbjct: 61 AGGHAEELVGIAMK---GQGIRRADYFLTDKVWKTHLRYDDVLRAAEASLKRLGTDYIDL 117
Query: 464 YLIHWPIAMFENDTLLDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGLEX 643
YLIH + +V +T R M K+ G+ + IG+SNF++E+++R +
Sbjct: 118 YLIH---------QVNPDVPEEETIRAMNRLKREGVIRHIGVSNFSEERLKRAQAASDAP 168
Query: 644 PSALQIELNLNLQQPE---LFKFCRENDIVVMAYTPFGSL 754
A Q+ NL +++ E L +CR DI+V+A+ P L
Sbjct: 169 IVANQLHYNLRIREIEQCGLLDYCRSQDIMVIAWRPLRGL 208
>UniRef50_Q4FY75 Cluster: Aldo-keto reductase-like protein; n=5;
Trypanosomatidae|Rep: Aldo-keto reductase-like protein -
Leishmania major strain Friedlin
Length = 372
Score = 96.7 bits (230), Expect = 7e-19
Identities = 63/199 (31%), Positives = 97/199 (48%), Gaps = 23/199 (11%)
Frame = +2
Query: 221 NDTEQAVIYALEAGYTHIDTAYKYGIEDQVGRALTKKF-SEGLKRESIFITTKLWNSYHE 397
++ AV +AL GY H+D A YG E VG AL + + +RE +F+T+KLW +
Sbjct: 43 SEATDAVAFALSCGYRHVDCAKAYGNEAAVGEALAQALRTRCTRREDLFVTSKLWPTDQH 102
Query: 398 REQVIPALRKSLENLNLEYVDLYLIHWPIAM-----FEND------------TLLDNVDF 526
+ V A R +L L L+Y+DLYLIHWP+ M + +D + +V
Sbjct: 103 PDHVEAACRATLAALQLDYLDLYLIHWPVCMRHTPHWTSDEDRYPRHRDGTPAIDTSVTL 162
Query: 527 LDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGLE-----XPSALQIELNLNLQQPE 691
LDTW M GL KSIG++N + ++ + E P Q+E + + +
Sbjct: 163 LDTWTAMNRLVDRGLVKSIGLANCTTAHVNDLVKAVAEAKLAHLPVLNQVEHHPGIVDGD 222
Query: 692 LFKFCRENDIVVMAYTPFG 748
L +D+++ AY P G
Sbjct: 223 LIGCLGSHDMLMAAYCPLG 241
>UniRef50_A6VNW9 Cluster: Aldo/keto reductase precursor; n=1;
Actinobacillus succinogenes 130Z|Rep: Aldo/keto
reductase precursor - Actinobacillus succinogenes 130Z
Length = 315
Score = 96.3 bits (229), Expect = 9e-19
Identities = 65/207 (31%), Positives = 107/207 (51%)
Frame = +2
Query: 128 TLQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQ 307
T++L++G +P++ +G W TE++V AL+AGY IDTA Y E
Sbjct: 44 TVKLNNGIEMPIIGIGVW---------TLTPEQTEKSVGEALKAGYRLIDTARMYRNEQA 94
Query: 308 VGRALTKKFSEGLKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPIA 487
VGRA+ G+ RE IFITTK++ S + A+ + L L+ +Y+DL L+H+P
Sbjct: 95 VGRAVR---DSGIPREEIFITTKIYGS-GDYANAEAAINERLRLLDTDYIDLLLLHYPD- 149
Query: 488 MFENDTLLDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGLEXPSALQIEL 667
+NDT W+ M K G ++IG+SN++++ RI+ + P+ +Q E+
Sbjct: 150 --QNDT--------KAWKVMEQFVKAGKIRAIGLSNYHRKTFNRIMQAATITPAVVQNEV 199
Query: 668 NLNLQQPELFKFCRENDIVVMAYTPFG 748
++ Q + F R + A+ P G
Sbjct: 200 HIYNQDKQTKAFLRNYGTQMEAWYPLG 226
>UniRef50_Q5V663 Cluster: Aldehyde reductase; n=6;
Halobacteriaceae|Rep: Aldehyde reductase - Haloarcula
marismortui (Halobacterium marismortui)
Length = 279
Score = 96.3 bits (229), Expect = 9e-19
Identities = 66/197 (33%), Positives = 100/197 (50%), Gaps = 1/197 (0%)
Frame = +2
Query: 155 IPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQVGRALTKKF 334
+P++ LGTW + ++V ALEAGY HIDTA Y E VG +
Sbjct: 17 MPMLGLGTWQN--------EDAEQCAESVRTALEAGYRHIDTAQAYDNESAVGDGIA--- 65
Query: 335 SEGLKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPIAMFENDTLLD 514
+ + R+ IF+ TK+W S + VI +SL+ L ++ VDL +HW +E + L
Sbjct: 66 AADVDRDDIFLATKVWISNLSHDDVIETTEESLDKLGVDSVDLLYVHWAAGEYEPEETLP 125
Query: 515 NVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGLEXP-SALQIELNLNLQQPE 691
D L RG+ID ++G+SNF ++ +D L+ P A Q+E + LQQ E
Sbjct: 126 AFDEL-VDRGLID--------NVGVSNFEPHHVETAMDV-LDAPVFANQVETHPFLQQSE 175
Query: 692 LFKFCRENDIVVMAYTP 742
L + E D ++AY+P
Sbjct: 176 LREHAAEQDYELVAYSP 192
>UniRef50_Q979I4 Cluster: Aldo / keto reductase; n=3; Archaea|Rep:
Aldo / keto reductase - Thermoplasma volcanium
Length = 288
Score = 95.9 bits (228), Expect = 1e-18
Identities = 67/202 (33%), Positives = 105/202 (51%), Gaps = 5/202 (2%)
Frame = +2
Query: 233 QAVIYALEAGYTHIDTAYKYGIEDQVGRALTKKFSEGLKRESIFITTKLWNSYHEREQVI 412
QA+ A++AG T IDTA YG ED V +A+ EG RE +FI TK+W ++ ++VI
Sbjct: 50 QAIRTAIDAGVTLIDTAEIYGSEDLVAKAI-----EGHNREELFIATKVWINHLRYDKVI 104
Query: 413 PALRKSLENLNLEYVDLYLIHWPIAMFENDTLLDNVDFLDTWRGMIDAKKLGLTKSIGIS 592
A + SL LN +YVDLY IH+P + +T++ M GL K IG+S
Sbjct: 105 KACKASLSRLNTKYVDLYQIHFP---------SPTANLQETFKAMEKLVDDGLVKFIGVS 155
Query: 593 NFNQEQIQRIIDSGLEXP-SALQIELNLNLQQPE--LFKFCRENDIVVMAYTPF--GSLF 757
NF++ ++++ ++ + + QI +L + E + KFC N + V+A+ P GSL
Sbjct: 156 NFSRGKLEKSMEYVKKYEIVSNQIHYSLKKRDAEEDIVKFCENNGMAVLAWYPLEHGSLV 215
Query: 758 PSKAQPDAPRRGLTMNVSSVSP 823
P + S++P
Sbjct: 216 RESDYPSEILARIKAKHPSITP 237
>UniRef50_Q11BF8 Cluster: Aldo/keto reductase; n=12; Bacteria|Rep:
Aldo/keto reductase - Mesorhizobium sp. (strain BNC1)
Length = 308
Score = 95.5 bits (227), Expect = 2e-18
Identities = 57/178 (32%), Positives = 93/178 (52%)
Frame = +2
Query: 221 NDTEQAVIYALEAGYTHIDTAYKYGIEDQVGRALTKKFSEGLKRESIFITTKLWNSYHER 400
++T AV AL GY HIDTA YG E +VG + + G+ R+ +FI TK+W S +
Sbjct: 42 DETTAAVEEALRLGYRHIDTAAAYGNEREVGEGIRRA---GIARDEVFIETKIWISDYGY 98
Query: 401 EQVIPALRKSLENLNLEYVDLYLIHWPIAMFENDTLLDNVDFLDTWRGMIDAKKLGLTKS 580
++ + A KS L ++ +DL L+H P+ + T L +R + G ++
Sbjct: 99 DETLHAFDKSAGKLGVDQIDLLLLHQPLPSAFDRT-------LGAYRALEKLLADGKVRA 151
Query: 581 IGISNFNQEQIQRIIDSGLEXPSALQIELNLNLQQPELFKFCRENDIVVMAYTPFGSL 754
IG+SNF E + R++ P+ QIE++ QQ L + E+ I+ A++P G +
Sbjct: 152 IGVSNFMPEHLTRLLTETSIVPAVNQIEVHPYFQQRALQRLHAEHGILTQAWSPIGGI 209
>UniRef50_Q572D2 Cluster: Aldo-keto reductase, putative; n=1;
Phytophthora infestans|Rep: Aldo-keto reductase,
putative - Phytophthora infestans (Potato late blight
fungus)
Length = 255
Score = 95.5 bits (227), Expect = 2e-18
Identities = 62/194 (31%), Positives = 99/194 (51%)
Frame = +2
Query: 122 VPTLQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIE 301
VPT L SG IP++ LG + + +T A++ +L+ GY HIDTA YG E
Sbjct: 5 VPTKILPSGARIPMIGLGVYQS--------EPGPETYNAILTSLKLGYRHIDTAEIYGNE 56
Query: 302 DQVGRALTKKFSEGLKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWP 481
+ VGRA+ G+ RE IF+TTKL+ + + + A + S + L + Y+ LYL+H P
Sbjct: 57 EDVGRAVR---DSGIPREEIFVTTKLFTTNWGYSKALAAGKASNDRLGIVYIYLYLLHAP 113
Query: 482 IAMFENDTLLDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGLEXPSALQI 661
E DTWR + D ++ + IG+SNFN+ + + + P+ Q+
Sbjct: 114 GPPKER---------ADTWRAVEDLREQETLRDIGVSNFNETLLATLRKTAHIKPAVNQV 164
Query: 662 ELNLNLQQPELFKF 703
EL+ + + L +
Sbjct: 165 ELHPWMMRQSLVNY 178
>UniRef50_Q5V6N9 Cluster: Alcohol dehydrogenase; n=2;
Halobacteriaceae|Rep: Alcohol dehydrogenase - Haloarcula
marismortui (Halobacterium marismortui)
Length = 667
Score = 95.5 bits (227), Expect = 2e-18
Identities = 55/201 (27%), Positives = 100/201 (49%), Gaps = 25/201 (12%)
Frame = +2
Query: 224 DTEQAVIYALEAGYTHIDTAYKYGIEDQVGRALTKKFSEGLKRESIFITTKLWNSYHERE 403
D ++ AL+AGY +D+A YG E ++GR L + +R +FI K+W + H R+
Sbjct: 395 DRADSIAAALDAGYRLLDSAELYGNEHRIGRILAAPGAPDRRR--VFILGKVWRTNHRRK 452
Query: 404 QVIPALRKSLENLNLEYVDLYLIHWPIAMFENDTL------------------------- 508
++ A R SL+ L ++ D Y +HWP A+ +L
Sbjct: 453 HMLTACRSSLDELGIDAFDCYALHWPEALAHRGSLTRLAEKSVARQEALTFPKNDRGDIE 512
Query: 509 LDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGLEXPSALQIELNLNLQQP 688
D+V W + + G T+++G+ N +Q Q++ +I++G P+ +Q+E + Q
Sbjct: 513 TDSVSLQRAWENLEALHERGWTRTLGLCNVSQTQLETVIETGTVRPALVQVERHPYQPQT 572
Query: 689 ELFKFCRENDIVVMAYTPFGS 751
+L ++C E I V+A++P +
Sbjct: 573 DLIEYCHERGIRVVAHSPLSA 593
>UniRef50_Q8DK16 Cluster: Tlr1054 protein; n=6; Cyanobacteria|Rep:
Tlr1054 protein - Synechococcus elongatus
(Thermosynechococcus elongatus)
Length = 320
Score = 94.7 bits (225), Expect = 3e-18
Identities = 61/196 (31%), Positives = 100/196 (51%)
Frame = +2
Query: 155 IPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQVGRALTKKF 334
I + LGTW + ++ ++ + + A+EAG T IDTA YG E R +
Sbjct: 13 ITPLILGTWQAGKRWWVGIE-DEESIRTIRAAVEAGMTTIDTAEVYG-EGHSERIVAA-- 68
Query: 335 SEGLKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPIAMFENDTLLD 514
+ G R+ TK++ ++ + VI A +SL NLN +Y+DLY IHWP F ++
Sbjct: 69 AVGDLRDRCVYATKVFANHLRYKDVIAACERSLRNLNTDYIDLYQIHWPAGSFGSEI--- 125
Query: 515 NVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGLEXPSALQIELNLNLQQPEL 694
V +T + M++ + G ++IG+SNF++ Q+ + G L + EL
Sbjct: 126 -VPIEETMQAMVELQAAGKIRAIGVSNFSRAQLAEAMQYGRIESVQPPYSLFWRWAEAEL 184
Query: 695 FKFCRENDIVVMAYTP 742
FC E++I V+AY+P
Sbjct: 185 IPFCIEHEITVLAYSP 200
>UniRef50_Q1PV10 Cluster: Putative uncharacterized protein; n=1;
Candidatus Kuenenia stuttgartiensis|Rep: Putative
uncharacterized protein - Candidatus Kuenenia
stuttgartiensis
Length = 284
Score = 94.3 bits (224), Expect = 4e-18
Identities = 73/217 (33%), Positives = 113/217 (52%), Gaps = 15/217 (6%)
Frame = +2
Query: 137 LSSGGNIPVVALGTW-LGHRPKGKVVQVTNDTEQ--AVIYALEAGYTHIDTAYKYG---I 298
LS+ IPV+ LGTW +G G T D E A+ A++ G THID A Y
Sbjct: 6 LSNNIKIPVIGLGTWTIGG---GDEADTTYDKENISAIKTAIKLGITHIDNAEAYAQGHS 62
Query: 299 EDQVGRALTKKFSEGLKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHW 478
E+ VGRA+ GL R+S+FIT+K+ + + ++ + + SL+ LN +Y+DLYLIH
Sbjct: 63 EELVGRAIV-----GLDRKSLFITSKVSPEHLSYDNLLASAKGSLQRLNTDYIDLYLIHA 117
Query: 479 PIAMFENDTLLDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGLEXPSALQ 658
P + +DFL ++ K L + IG+SNF+ +QI+ A Q
Sbjct: 118 PNPDIPIQETMKAMDFL------VEQK---LVRCIGVSNFSVDQIKEAQKYTKNKIVANQ 168
Query: 659 IELNLNLQ---------QPELFKFCRENDIVVMAYTP 742
IE NL ++ + E+ +C+EN+I ++A+ P
Sbjct: 169 IEYNLLVRDKGRVTENMESEIIPYCQENNIFIIAWRP 205
>UniRef50_Q5KKZ8 Cluster: Aldo-keto reductase, putative; n=2;
Filobasidiella neoformans|Rep: Aldo-keto reductase,
putative - Cryptococcus neoformans (Filobasidiella
neoformans)
Length = 293
Score = 94.3 bits (224), Expect = 4e-18
Identities = 67/212 (31%), Positives = 108/212 (50%), Gaps = 7/212 (3%)
Frame = +2
Query: 128 TLQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQ 307
T++L+SG IP + G + + + E AV A++ GY H+DTA Y E+
Sbjct: 8 TIKLASGNLIPRLGFGVYQAR---------SKECEDAVKKAIDTGYRHVDTAQAYHNEEN 58
Query: 308 VGRALTKKFSEGLKRESIFITTKLWNSY--HEREQVIPALRKSLENL-----NLEYVDLY 466
VGRA+ + G+ R S+F+T+K S+ + +V+ +RKSL+ + + Y+DL
Sbjct: 59 VGRAIR---NSGVPRPSVFLTSKYMPSHTVYSPTEVLDVVRKSLKKVDRCGDDKPYIDLM 115
Query: 467 LIHWPIAMFENDTLLDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGLEXP 646
LIH P E + W + A+K G K IG+SNF ++ + P
Sbjct: 116 LIHAPWGGEEGRK--------NNWEALTIAQKEGWVKDIGVSNFGIHHLKALPP---PVP 164
Query: 647 SALQIELNLNLQQPELFKFCRENDIVVMAYTP 742
+ QIEL+ QQ ++ K+C E+ I + AY+P
Sbjct: 165 AVNQIELHPFCQQRDIVKYCEEHGIAIEAYSP 196
>UniRef50_A5DRJ6 Cluster: Putative uncharacterized protein; n=4;
Pichia guilliermondii|Rep: Putative uncharacterized
protein - Pichia guilliermondii (Yeast) (Candida
guilliermondii)
Length = 287
Score = 94.3 bits (224), Expect = 4e-18
Identities = 69/207 (33%), Positives = 104/207 (50%), Gaps = 5/207 (2%)
Frame = +2
Query: 137 LSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQVGR 316
L +G IP +G +L + T V AL+ GY IDTA +Y E + G
Sbjct: 12 LLNGSRIPACGVGVYL---------LPASQTAGIVEKALDVGYRLIDTAQEYENERETGE 62
Query: 317 ALTKKFSEGL--KRESIFITTKLWNSYHEREQVIPALRKSLENL-NLEYVDLYLIHWPIA 487
+ + KRE + TTK+ N ++ +L++SL + +LEY+DL LIH
Sbjct: 63 GIKAWLGKDKNNKREDVLYTTKITNLNQGYDRTWRSLKESLNKVKHLEYIDLVLIH---- 118
Query: 488 MFENDTLLDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIID-SGLE-XPSALQI 661
D L D ++TW+ + +A G+ KSIG+SNF + IQ + D GL+ P QI
Sbjct: 119 ----DPLSDKKTRIETWKALQEAVDSGMVKSIGVSNFGKHHIQELYDWEGLKYKPIVNQI 174
Query: 662 ELNLNLQQPELFKFCRENDIVVMAYTP 742
EL+ L + +L +C+ IV+ AY P
Sbjct: 175 ELSPWLMRKDLVDYCQNLGIVLEAYCP 201
>UniRef50_Q4P1G1 Cluster: Putative uncharacterized protein; n=1;
Ustilago maydis|Rep: Putative uncharacterized protein -
Ustilago maydis (Smut fungus)
Length = 320
Score = 93.9 bits (223), Expect = 5e-18
Identities = 64/186 (34%), Positives = 99/186 (53%), Gaps = 1/186 (0%)
Frame = +2
Query: 122 VPTLQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIE 301
+PT++L+SG +P +A GT G + +D + V AL++G+ ID A Y E
Sbjct: 3 IPTVRLASGLELPRLAFGT-------GTALY-NSDAAKQVTMALDSGFRFIDGAEVYANE 54
Query: 302 DQVGRALTKKF-SEGLKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHW 478
+G + S GLKR I++ TK+ + Q A++ L+ L ++ +D YL+H
Sbjct: 55 ASMGAGIESFLASSGLKRNDIYVLTKVGKEGMKDLQ--SAIKVELQKLKVDQLDSYLLHL 112
Query: 479 PIAMFENDTLLDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGLEXPSALQ 658
P D L NVD W+ + K+ GLTKSIG+SN+ IQ+++D+GL P Q
Sbjct: 113 PPR--GQDGLPSNVD---AWKELEKIKQAGLTKSIGVSNWLASDIQQLLDAGLSVPDINQ 167
Query: 659 IELNLN 676
IE + N
Sbjct: 168 IEFHNN 173
>UniRef50_A4YQ04 Cluster: 2,5-diketo-D-gluconate reductase B; n=15;
Proteobacteria|Rep: 2,5-diketo-D-gluconate reductase B -
Bradyrhizobium sp. (strain ORS278)
Length = 273
Score = 93.5 bits (222), Expect = 7e-18
Identities = 63/202 (31%), Positives = 104/202 (51%), Gaps = 1/202 (0%)
Frame = +2
Query: 140 SSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQVGRA 319
+ G +P + LGT+ R +G V + AV AL GY HIDTA Y ED +G A
Sbjct: 6 TQGVRLPKLGLGTF---RMQGTVCR------DAVESALALGYRHIDTAEMYANEDAIGAA 56
Query: 320 LTKKFSEGLKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPIAMFEN 499
L + + RE + +TTK+W + + A SL+ L L++VDLYLIHWP
Sbjct: 57 LA---AAQIAREDLHVTTKVWPENLAPDAIRRAFDTSLKKLRLDFVDLYLIHWPATGMNL 113
Query: 500 DTLLDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGLEXPSAL-QIELNLN 676
++ ++ K+ G T++IG++NF +++ ++ ++ P A Q+E ++
Sbjct: 114 PAAMET---------LMALKQEGRTRAIGVANFTVALLKQAVED-IQAPVACNQVEYHVM 163
Query: 677 LQQPELFKFCRENDIVVMAYTP 742
L Q +L + + I ++AY P
Sbjct: 164 LDQSKLMAYMKSRSIPLVAYCP 185
>UniRef50_Q09632 Cluster: Probable oxidoreductase ZK1290.5; n=2;
Caenorhabditis|Rep: Probable oxidoreductase ZK1290.5 -
Caenorhabditis elegans
Length = 321
Score = 93.5 bits (222), Expect = 7e-18
Identities = 66/210 (31%), Positives = 111/210 (52%), Gaps = 2/210 (0%)
Frame = +2
Query: 119 IVPTLQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALE-AGYTHIDTAYKYG 295
++PT LS+ +P++ LGT AV+++++ GY IDTA +YG
Sbjct: 1 MIPTTVLSNNVEMPLIGLGT----------THSGGYYHDAVLHSIKKCGYRLIDTAKRYG 50
Query: 296 IEDQVGRALTKKFSEGLKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIH 475
+E Q+G A+ K S + RE +F++TKLW ++V A + S E L +Y+D+Y+IH
Sbjct: 51 VEKQLGIAV-KNCS--VPREEMFLSTKLW-PVDCGDEVYNAFQTSCEKLQTDYLDMYMIH 106
Query: 476 WPIAMFENDTLLDNVDFLD-TWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGLEXPSA 652
P D +++ + + TWR M + +SIG+SN++ E + +++ P A
Sbjct: 107 MPQLP---DWIVNQKETKEKTWRQMELLYEDEHVRSIGVSNYSIEDLDELLEFASILPHA 163
Query: 653 LQIELNLNLQQPELFKFCRENDIVVMAYTP 742
Q+EL+ Q +L +C E I+ M Y P
Sbjct: 164 NQVELHPWFHQADLKNYCDELGILTMGYCP 193
>UniRef50_UPI000155CAC7 Cluster: PREDICTED: hypothetical protein;
n=1; Ornithorhynchus anatinus|Rep: PREDICTED:
hypothetical protein - Ornithorhynchus anatinus
Length = 419
Score = 93.1 bits (221), Expect = 9e-18
Identities = 59/145 (40%), Positives = 82/145 (56%), Gaps = 1/145 (0%)
Frame = +2
Query: 116 LIVPTLQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYAL-EAGYTHIDTAYKY 292
L VPT+ L++G NIP++ LGT H V + AVIYAL E G HIDTA +Y
Sbjct: 10 LPVPTVPLANGLNIPILGLGT--SH--------VGGYSHDAVIYALKECGIRHIDTAKRY 59
Query: 293 GIEDQVGRALTKKFSEGLKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLI 472
G E +G+A+ + G+KRE ++ITTKLW + + E + +S L +EY+DL+LI
Sbjct: 60 GCELLLGKAIQES---GVKREELWITTKLWLTDYGYESAKQSCLESCNRLGVEYLDLFLI 116
Query: 473 HWPIAMFENDTLLDNVDFLDTWRGM 547
HWP A + +TWR M
Sbjct: 117 HWPDAQLPGKS--SREARAETWRAM 139
>UniRef50_A6RMS0 Cluster: Putative uncharacterized protein; n=1;
Botryotinia fuckeliana B05.10|Rep: Putative
uncharacterized protein - Botryotinia fuckeliana B05.10
Length = 286
Score = 93.1 bits (221), Expect = 9e-18
Identities = 67/207 (32%), Positives = 102/207 (49%)
Frame = +2
Query: 128 TLQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQ 307
+ +L +G +P + LGT+ G KV + V A++AGY HID A YG E+
Sbjct: 7 SFRLVNGSTLPAIGLGTFQGDDGNEKVKNI-------VKAAIQAGYRHIDGAAAYGNEEA 59
Query: 308 VGRALTKKFSEGLKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPIA 487
+G A+ + G+ R+ +L +HE + V AL SLE L LEYV + P
Sbjct: 60 IGDAIKES---GISRD------ELAQPWHEPKDVERALDLSLEALGLEYVPHAYLPGP-- 108
Query: 488 MFENDTLLDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGLEXPSALQIEL 667
N + + +TW+ M G K+IG+SNFN + +RI++ P+ Q+E
Sbjct: 109 --NNVDYERSRKYTETWQAMEKLVDSGKAKAIGLSNFNILKTKRILEIARIRPAVNQVEA 166
Query: 668 NLNLQQPELFKFCRENDIVVMAYTPFG 748
+ Q EL FC + I +MA+ P G
Sbjct: 167 HPYFPQHELLAFCEKEHIHLMAHQPLG 193
>UniRef50_Q3CZS2 Cluster: Oxidoreductase, aldo/keto reductase
family; n=2; Streptococcus agalactiae|Rep:
Oxidoreductase, aldo/keto reductase family -
Streptococcus agalactiae H36B
Length = 245
Score = 92.3 bits (219), Expect = 2e-17
Identities = 58/174 (33%), Positives = 93/174 (53%)
Frame = +2
Query: 224 DTEQAVIYALEAGYTHIDTAYKYGIEDQVGRALTKKFSEGLKRESIFITTKLWNSYHERE 403
+ EQ+V+ AL+ GY IDTA Y E+ VGRA+ K G+ R+ IF+ TKLW E
Sbjct: 30 ECEQSVLDALQVGYRLIDTASGYLNEEAVGRAIKKS---GIPRKEIFVVTKLWIQDASEE 86
Query: 404 QVIPALRKSLENLNLEYVDLYLIHWPIAMFENDTLLDNVDFLDTWRGMIDAKKLGLTKSI 583
+ PA+ ++L+ L L+Y++LYLIH P+ D+ R + A + +I
Sbjct: 87 KAGPAIDRALKRLQLDYINLYLIHQPMG-----------DYYGACRALEKAYEERKALAI 135
Query: 584 GISNFNQEQIQRIIDSGLEXPSALQIELNLNLQQPELFKFCRENDIVVMAYTPF 745
G+SNF+ ++Q +I P+ QI++N + ++ + I MA+ PF
Sbjct: 136 GVSNFSNGRVQDLILHNKIIPAVNQIQMNPFHPAKDQVEWLSKKGIHTMAWGPF 189
>UniRef50_Q4WUF7 Cluster: Aldo-keto reductase, putative; n=3;
Pezizomycotina|Rep: Aldo-keto reductase, putative -
Aspergillus fumigatus (Sartorya fumigata)
Length = 283
Score = 92.3 bits (219), Expect = 2e-17
Identities = 70/215 (32%), Positives = 107/215 (49%), Gaps = 3/215 (1%)
Frame = +2
Query: 107 SADLIVPTLQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAY 286
S+ L + L ++ + LG + P G+ VQ + + ALEAGY HIDTA
Sbjct: 2 SSKLTITDLLPLPNSDVKIPRLGFGVYRSPTGQCVQSS-------LRALEAGYRHIDTAQ 54
Query: 287 KYGIEDQVGRALTKKFSEGLKRESIFITTKLWNSYHEREQVIPALRKSLENLNLE--YVD 460
YG E +VG AL K G+ R +F+TTK+ + E L +S+E + YVD
Sbjct: 55 FYGNEKEVGEALRKC---GIPRSDVFVTTKILSPAGSPEATYQKLLESVEKIGGRDGYVD 111
Query: 461 LYLIHWPIAMFENDTLLDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRI-IDSGL 637
L+LIH + + + W+ + + G T+SIG+SNF + I+ + + +
Sbjct: 112 LFLIH--------SSSSGSAGRKELWQALERLLEEGKTRSIGVSNFGVKHIEEMKAYAKV 163
Query: 638 EXPSALQIELNLNLQQPELFKFCRENDIVVMAYTP 742
P QIEL+ QQ + +C+ N IVV AY+P
Sbjct: 164 WPPHVNQIELHPWCQQRVIEAYCKRNGIVVEAYSP 198
>UniRef50_Q5NLW3 Cluster: Putative oxidoreductase; n=1; Zymomonas
mobilis|Rep: Putative oxidoreductase - Zymomonas mobilis
Length = 273
Score = 91.9 bits (218), Expect = 2e-17
Identities = 62/174 (35%), Positives = 87/174 (50%), Gaps = 1/174 (0%)
Frame = +2
Query: 230 EQAVIYALEAGYTHIDTAYKYGIEDQVGRALTKKFSEGLKRESIFITTKLWNSYHEREQV 409
E V + GY +DTA Y E+ VG L + + FITTKL R
Sbjct: 31 ESMVALGYDLGYRAVDTAAWYENEEGVGEGLRSRHARS------FITTKLMPQDMGRVNC 84
Query: 410 IPALRKSLENLNLEYVDLYLIHWPIAMFENDTLLDNVDFLDTWRGMIDAKKLGLTKSIGI 589
AL KS+ NL + ++LYLIHWP D + +TW+ +I + +G SIG+
Sbjct: 85 FVALDKSIRNLGVTSLNLYLIHWPGQ--------DRKRYEETWQTLIQIRAIGKASSIGV 136
Query: 590 SNFNQEQIQRII-DSGLEXPSALQIELNLNLQQPELFKFCRENDIVVMAYTPFG 748
SNF + + II DSG+ P+ QIEL+ QQ EL + E IV +++P G
Sbjct: 137 SNFTIDHLDHIIADSGV-VPAVNQIELHPYFQQKELRAYHAERGIVTTSWSPLG 189
>UniRef50_A4FEB9 Cluster: 2,5-diketo-D-gluconic acid reductase; n=1;
Saccharopolyspora erythraea NRRL 2338|Rep:
2,5-diketo-D-gluconic acid reductase - Saccharopolyspora
erythraea (strain NRRL 23338)
Length = 159
Score = 91.5 bits (217), Expect = 3e-17
Identities = 56/121 (46%), Positives = 70/121 (57%), Gaps = 1/121 (0%)
Frame = +2
Query: 122 VPTLQLSSGGNIPVVALGTWLGHRPKGKVVQVTND-TEQAVIYALEAGYTHIDTAYKYGI 298
VPT+ L++G +P + G V QV D T AV ALEAGY IDTA YG
Sbjct: 4 VPTVTLNNGVEMPQLGYG----------VFQVPEDETAAAVGAALEAGYRSIDTAAAYGN 53
Query: 299 EDQVGRALTKKFSEGLKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHW 478
E VGRAL GL R+ +F+TTKLWN+ + + A SLE L L+++DLYLIHW
Sbjct: 54 EAAVGRALA---GSGLARDELFVTTKLWNADQGYDNALRAFDTSLELLGLDHLDLYLIHW 110
Query: 479 P 481
P
Sbjct: 111 P 111
>UniRef50_P91997 Cluster: Putative uncharacterized protein; n=4;
Caenorhabditis|Rep: Putative uncharacterized protein -
Caenorhabditis elegans
Length = 297
Score = 91.5 bits (217), Expect = 3e-17
Identities = 62/206 (30%), Positives = 109/206 (52%), Gaps = 4/206 (1%)
Frame = +2
Query: 134 QLSSGGNIPVVALGTWLGHRPKGKVVQVTNDT-EQAVIYALEAGYTHIDTAYKYGIEDQV 310
+L+SG NIP V GT+ +VT + A+ AL AGY DTA Y E ++
Sbjct: 14 KLNSGYNIPFVGFGTY----------KVTGENVPPAIDAALTAGYRMFDTAKYYLNEKEL 63
Query: 311 GRALTKKFSE-GLKRESIFITTKLW-NSYHEREQVIPALRKSLENLNLEYVDLYLIHWPI 484
G AL + GL R +F+T+K + S + RE + +SL++L +Y+D+YL+H+P
Sbjct: 64 GEALKILLPKHGLSRSDVFLTSKFFPESKNCREACRGFVEESLQSLQTDYIDMYLVHYPK 123
Query: 485 AMFENDTLLDNVDFLD-TWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGLEXPSALQI 661
++ ++N ++ + + +AK G +SIG+SN+ ++ + P A Q+
Sbjct: 124 PNDSDNDDVNNAEYRKIAYEVLEEAKAAGKVRSIGVSNYEIVHLEELKTYAKVPPCANQL 183
Query: 662 ELNLNLQQPELFKFCRENDIVVMAYT 739
E + + + L K+C+E +I A++
Sbjct: 184 EYHPHFARIPLQKYCKEKNIFFQAFS 209
>UniRef50_A1RB46 Cluster: 2,5-diketo-D-gluconate reductase; n=1;
Arthrobacter aurescens TC1|Rep: 2,5-diketo-D-gluconate
reductase - Arthrobacter aurescens (strain TC1)
Length = 273
Score = 91.1 bits (216), Expect = 3e-17
Identities = 62/202 (30%), Positives = 97/202 (48%), Gaps = 1/202 (0%)
Frame = +2
Query: 134 QLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQVG 313
Q S+G +P + LGT G RP D + V +AL+ GY DTA YG E +G
Sbjct: 3 QHSAGTALPAITLGT--GLRPP-------TDVYRLVGWALDMGYRSFDTAALYGTEAAIG 53
Query: 314 RALTKKFSEGLKRESIFITTKL-WNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPIAM 490
RA+ G+ R +FIT K+ N Y R +V A+ +SLE L + D+ + HWP+ M
Sbjct: 54 RAIR---DSGIDRRELFITVKVRGNEYGSRARVHQAIERSLEALGTSFADMVVPHWPLPM 110
Query: 491 FENDTLLDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGLEXPSALQIELN 670
T+ M+DA+ GL + +G+SN + ++ + E P Q+ L+
Sbjct: 111 VR--------ALPSTFAQMLDARSEGLVRGVGLSNASSAMVRAVRTETGEWPVVNQLHLS 162
Query: 671 LNLQQPELFKFCRENDIVVMAY 736
+ Q + +F + + AY
Sbjct: 163 PIVGQTDFTRFAETVPVGIQAY 184
>UniRef50_O14088 Cluster: Xylose and arabinose reductase; n=1;
Schizosaccharomyces pombe|Rep: Xylose and arabinose
reductase - Schizosaccharomyces pombe (Fission yeast)
Length = 275
Score = 91.1 bits (216), Expect = 3e-17
Identities = 66/216 (30%), Positives = 107/216 (49%), Gaps = 4/216 (1%)
Frame = +2
Query: 131 LQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQV 310
++L++G P A G+++ +R K +V AL+ GY HID+A Y E
Sbjct: 6 VKLNNGLKCPQFAYGSYMVNRTK---------CFDSVYAALQCGYRHIDSAQMYHNEADC 56
Query: 311 GRALTKKFSE-GLKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPIA 487
GRA+ K E G KRE I+ T+KL N + + ++ S++ L Y+DL+L+H P
Sbjct: 57 GRAILKFMEETGTKREDIWFTSKL-NDLSGYKSTLSSIDASVKACGLGYIDLFLLHSPYG 115
Query: 488 MFENDTLLDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGLE-XPSALQIE 664
D +++W+ + + G ++IG+SNF IQ ++DS + P QIE
Sbjct: 116 -----------DRIESWKALEKGVEEGKLRAIGVSNFGPHHIQELLDSHPKIIPCVNQIE 164
Query: 665 LNLNLQQPELFKFCRENDIVVMAYTPF--GSLFPSK 766
L+ Q ++ +C I + AY P G F +K
Sbjct: 165 LHPFCSQQKVVDYCESKGIQLAAYAPLVHGEKFGNK 200
>UniRef50_Q9C1X5 Cluster: Xylose and arabinose reductase; n=1;
Schizosaccharomyces pombe|Rep: Xylose and arabinose
reductase - Schizosaccharomyces pombe (Fission yeast)
Length = 283
Score = 90.6 bits (215), Expect = 5e-17
Identities = 59/176 (33%), Positives = 93/176 (52%), Gaps = 2/176 (1%)
Frame = +2
Query: 221 NDTEQAVIYALEAGYTHIDTAYKYGIEDQVGRALTKKFSE-GLKRESIFITTKLWNSYHE 397
N+ V AL++GY HIDTA YG ED G+A+ + +KR IF+T+KL N +
Sbjct: 32 NECYGLVTQALDSGYRHIDTAAVYGNEDICGKAIVDWCEKNNVKRTDIFLTSKLANC-SD 90
Query: 398 REQVIPALRKSLENLNLEYVDLYLIHWPIAMFENDTLLDNVDFLDTWRGMIDAKKLGLTK 577
A+R SL +L Y+DL+LI P + +W+ M + G +
Sbjct: 91 YYSTRAAIRSSLHHLG-TYIDLFLIQSPAG--------GKKSRIASWKAMEEFVDSGDIR 141
Query: 578 SIGISNFNQEQIQRIIDSGLE-XPSALQIELNLNLQQPELFKFCRENDIVVMAYTP 742
S+G+SN+ + +Q + S + P QIEL+ L Q ++ K+C+ +DI + AY+P
Sbjct: 142 SVGVSNYGVKHLQELYASNPKFYPCVNQIELHPFLSQDDIVKYCQSHDIAIEAYSP 197
>UniRef50_Q59ZT1 Cluster: Putative uncharacterized protein; n=1;
Candida albicans|Rep: Putative uncharacterized protein -
Candida albicans (Yeast)
Length = 259
Score = 90.6 bits (215), Expect = 5e-17
Identities = 69/227 (30%), Positives = 112/227 (49%), Gaps = 9/227 (3%)
Frame = +2
Query: 128 TLQLSSGGNIPV-VALGTWLGHRPKGKVVQVTNDTEQAVI----YALEAGYTHIDTAYKY 292
TL SG I + + GT + +G Q T + + ++ YAL GY HIDTA Y
Sbjct: 2 TLTTVSGDPITIGIGTGTSIKDLKRG---QPTAENKARIVDILRYALSIGYNHIDTAEVY 58
Query: 293 GIEDQVGRALTKKFSEGLKRESIFITTK--LWNSYHEREQVIPA--LRKSLENLNLEYVD 460
+ +VG A+ G +RE ++ITTK + +S +++ P + ++L+ +N Y+D
Sbjct: 59 TTQPEVGTAIA-----GFQREKLWITTKYSVTSSMIKKKSFTPTDFVEQALDEMNTNYID 113
Query: 461 LYLIHWPIAMFENDTLLDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGLE 640
L LIH+P ND W+ + K G + IG+SNF+ Q+ +++ G
Sbjct: 114 LLLIHFPPK--PNDP----YTIQSLWQEFVSIKATGKVRYIGVSNFDIPQLNTLLEIG-- 165
Query: 641 XPSALQIELNLNLQQPELFKFCRENDIVVMAYTPFGSLFPSKAQPDA 781
P+ QI+ L E+ +FC+ + I+V AY P L + DA
Sbjct: 166 TPTINQIQYYLGSDNLEVVEFCKNHGILVEAYGPLTPLRNPNPKTDA 212
Database: uniref50
Posted date: Oct 5, 2007 11:19 AM
Number of letters in database: 575,637,011
Number of sequences in database: 1,657,284
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 901,559,251
Number of Sequences: 1657284
Number of extensions: 19549415
Number of successful extensions: 60470
Number of sequences better than 10.0: 500
Number of HSP's better than 10.0 without gapping: 56984
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 59503
length of database: 575,637,011
effective HSP length: 100
effective length of database: 409,908,611
effective search space used: 80342087756
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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