BLASTX 2.2.12 [Aug-07-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= MFBP02_F_N18 (892 letters) Database: human 237,096 sequences; 76,859,062 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value AB209017-1|BAD92254.1| 286|Homo sapiens aldo-keto reductase fam... 159 9e-39 U05861-1|AAA18115.1| 323|Homo sapiens hepatic dihydrodiol dehyd... 159 1e-38 U05684-1|AAA16227.1| 323|Homo sapiens dihydrodiol dehydrogenase... 159 1e-38 M86609-1|AAB02880.1| 323|Homo sapiens dihydrodiol dehydrogenase... 159 1e-38 BT007197-1|AAP35861.1| 323|Homo sapiens aldo-keto reductase fam... 159 1e-38 BC040210-1|AAH40210.1| 323|Homo sapiens aldo-keto reductase fam... 159 1e-38 BC020216-1|AAH20216.1| 323|Homo sapiens aldo-keto reductase fam... 159 1e-38 BC015490-1|AAH15490.1| 323|Homo sapiens aldo-keto reductase fam... 159 1e-38 AL713867-2|CAI16409.1| 323|Homo sapiens aldo-keto reductase fam... 159 1e-38 AB032150-1|BAA92886.1| 323|Homo sapiens 20 alph-hydroxysteroid ... 159 1e-38 AB031083-1|BAA92883.1| 323|Homo sapiens 20 alpha-hydroxysteroid... 159 1e-38 U05598-1|AAA20937.1| 323|Homo sapiens dihydrodiol dehydrogenase... 159 2e-38 S68330-1|AAD14013.1| 323|Homo sapiens chlordecone reductase hom... 159 2e-38 L32592-1|AAB38486.1| 323|Homo sapiens dihydrodiol dehydrogenase... 159 2e-38 BT006653-1|AAP35299.1| 323|Homo sapiens aldo-keto reductase fam... 159 2e-38 BC063574-1|AAH63574.1| 323|Homo sapiens aldo-keto reductase fam... 159 2e-38 BC007024-1|AAH07024.1| 323|Homo sapiens aldo-keto reductase fam... 159 2e-38 AL713867-1|CAI16408.1| 323|Homo sapiens aldo-keto reductase fam... 159 2e-38 AL391427-1|CAI14726.1| 323|Homo sapiens aldo-keto reductase fam... 159 2e-38 AB032153-1|BAA92891.1| 323|Homo sapiens bile acid-binding prote... 159 2e-38 AB031084-1|BAA92884.1| 323|Homo sapiens bile acid-binding prote... 159 2e-38 AB021654-1|BAA36169.1| 323|Homo sapiens DD2/bile acid-binding p... 159 2e-38 CR542203-1|CAG47000.1| 316|Homo sapiens AKR1B1 protein. 157 7e-38 J04794-1|AAA51711.1| 325|Homo sapiens ALDR1 protein. 156 9e-38 CR457010-1|CAG33291.1| 325|Homo sapiens AKR1A1 protein. 156 9e-38 BT007003-1|AAP35649.1| 325|Homo sapiens aldo-keto reductase fam... 156 9e-38 BC005394-1|AAH05394.1| 325|Homo sapiens aldo-keto reductase fam... 156 9e-38 BC000670-1|AAH00670.1| 325|Homo sapiens aldo-keto reductase fam... 156 9e-38 AL355480-3|CAI22459.1| 325|Homo sapiens aldo-keto reductase fam... 156 9e-38 AF112485-1|AAF01260.1| 325|Homo sapiens aldehyde reductase prot... 156 9e-38 AF036683-1|AAB92369.1| 325|Homo sapiens aldehyde reductase prot... 156 9e-38 BC020744-1|AAH20744.1| 323|Homo sapiens aldo-keto reductase fam... 156 1e-37 AB045829-1|BAA99542.1| 323|Homo sapiens 3alpha-hydroxysteroid d... 155 2e-37 S68287-1|AAD14010.1| 323|Homo sapiens chlordecone reductase pro... 155 2e-37 D26125-1|BAA05122.1| 321|Homo sapiens 3 alpha-hydroxysteroid/di... 155 2e-37 AL355303-2|CAI14202.1| 323|Homo sapiens aldo-keto reductase fam... 155 2e-37 AB032163-1|BAA92893.1| 323|Homo sapiens dihydrodiol dehydrogena... 155 2e-37 AB031085-1|BAA92885.1| 323|Homo sapiens dihydrodiol dehydrogena... 155 2e-37 X15414-1|CAA33460.1| 316|Homo sapiens protein ( Human mRNA for ... 155 3e-37 M59783-1|AAA51712.1| 316|Homo sapiens aldose reductase protein. 155 3e-37 M34720-1|AAA35560.1| 316|Homo sapiens protein ( Human aldose re... 155 3e-37 J05474-1|AAA51715.1| 316|Homo sapiens aldose reductase protein. 155 3e-37 J04795-1|AAA51713.1| 316|Homo sapiens ALDR1 protein. 155 3e-37 D17793-1|BAA04619.2| 325|Homo sapiens KIAA0119 protein. 155 3e-37 BT019859-1|AAV38662.1| 316|Homo sapiens aldo-keto reductase fam... 155 3e-37 BT007286-1|AAP35950.1| 323|Homo sapiens aldo-keto reductase fam... 155 3e-37 BC019230-1|AAH19230.1| 323|Homo sapiens aldo-keto reductase fam... 155 3e-37 BC010391-1|AAH10391.1| 316|Homo sapiens aldo-keto reductase fam... 155 3e-37 BC001479-1|AAH01479.1| 323|Homo sapiens aldo-keto reductase fam... 155 3e-37 BC000260-1|AAH00260.1| 316|Homo sapiens aldo-keto reductase fam... 155 3e-37 AL391427-4|CAI14729.1| 323|Homo sapiens aldo-keto reductase fam... 155 3e-37 AF328729-1|AAN09721.1| 316|Homo sapiens CTCL tumor antigen HD-C... 155 3e-37 AF032455-1|AAB88851.1| 316|Homo sapiens aldose reductase protein. 155 3e-37 AB209796-1|BAD93033.1| 260|Homo sapiens aldo-keto reductase fam... 155 3e-37 AB032157-1|BAA92892.1| 323|Homo sapiens prostaglandin F synthas... 155 3e-37 AB018580-1|BAA88488.1| 323|Homo sapiens hluPGFS protein. 155 3e-37 U37100-1|AAC17469.1| 316|Homo sapiens aldose reductase-like pep... 154 4e-37 CR541801-1|CAG46600.1| 316|Homo sapiens AKR1B10 protein. 154 4e-37 CR450351-1|CAG29347.1| 316|Homo sapiens AKR1B1 protein. 154 4e-37 BT006794-1|AAP35440.1| 316|Homo sapiens aldo-keto reductase fam... 154 4e-37 BC008837-1|AAH08837.1| 316|Homo sapiens aldo-keto reductase fam... 154 4e-37 AF052577-1|AAC36465.1| 316|Homo sapiens aldo-keto reductase pro... 154 4e-37 J05017-1|AAA51714.1| 316|Homo sapiens ALDR1 protein. 154 5e-37 S68290-1|AAD14012.1| 320|Homo sapiens chlordecone reductase hom... 153 1e-36 D26124-1|BAA05121.1| 306|Homo sapiens dihydrodiol dehydrogenase... 153 1e-36 S68288-1|AAD14011.1| 323|Homo sapiens chlordecone reductase hom... 152 1e-36 M33375-1|AAA35658.1| 308|Homo sapiens protein ( Human chlordeco... 151 3e-36 L43839-1|AAB41916.1| 323|Homo sapiens 3-alpha-hydroxysteroid de... 151 3e-36 DQ269985-1|ABB76132.1| 323|Homo sapiens type II 3a-hydroxystero... 151 3e-36 AF524864-1|AAO13380.1| 316|Homo sapiens aldo-ketoreductase prot... 151 3e-36 AF149416-1|AAF07272.2| 323|Homo sapiens 3-alpha hydroxysteroid ... 151 3e-36 BC005387-1|AAH05387.1| 316|Homo sapiens aldo-keto reductase fam... 149 1e-35 AF263242-1|AAK58523.1| 320|Homo sapiens aldo-keto reductase loo... 95 4e-35 BC002862-1|AAH02862.1| 307|Homo sapiens AKR1CL2 protein protein. 95 4e-35 AB055603-1|BAC54568.1| 307|Homo sapiens aldo-keto reductase rel... 95 4e-35 Z28339-1|CAA82193.1| 326|Homo sapiens delta 4-3-oxosteroid 5 be... 146 9e-35 BC130627-1|AAI30628.1| 326|Homo sapiens aldo-keto reductase fam... 146 9e-35 BC130625-1|AAI30626.1| 326|Homo sapiens aldo-keto reductase fam... 146 9e-35 AF283659-1|AAG39381.1| 326|Homo sapiens 5-beta steroid reductas... 146 9e-35 AL713867-3|CAI16410.1| 247|Homo sapiens aldo-keto reductase fam... 127 6e-29 AB040821-1|BAC54566.1| 263|Homo sapiens aldo-keto reductase rel... 95 8e-29 AB040820-1|BAC54565.1| 250|Homo sapiens aldo-keto reductase rel... 95 8e-29 AL391427-2|CAI14727.1| 302|Homo sapiens aldo-keto reductase fam... 111 4e-24 AL355303-1|CAI14201.1| 302|Homo sapiens aldo-keto reductase fam... 111 4e-24 AL355480-2|CAI22458.1| 147|Homo sapiens aldo-keto reductase fam... 108 2e-23 BC101205-1|AAI01206.1| 129|Homo sapiens aldo-keto reductase fam... 97 6e-20 BC101204-1|AAI01205.1| 129|Homo sapiens aldo-keto reductase fam... 97 6e-20 AK131335-1|BAD18494.1| 129|Homo sapiens protein ( Homo sapiens ... 97 6e-20 AB040822-1|BAC54567.1| 222|Homo sapiens aldo-keto reductase rel... 95 2e-19 AB037902-1|BAA92887.1| 130|Homo sapiens truncated aldo-keto red... 90 9e-18 AK058142-1|BAB71682.1| 146|Homo sapiens protein ( Homo sapiens ... 71 4e-12 U33429-1|AAC50955.1| 367|Homo sapiens K+ channel beta 2 subunit... 49 2e-05 CR542287-1|CAG47082.1| 353|Homo sapiens KCNAB2 protein. 49 2e-05 BC130413-1|AAI30414.1| 367|Homo sapiens potassium voltage-gated... 49 2e-05 BC126424-1|AAI26425.1| 367|Homo sapiens potassium voltage-gated... 49 2e-05 BC110351-1|AAI10352.1| 395|Homo sapiens KCNAB2 protein protein. 49 2e-05 AL035406-6|CAI19886.1| 253|Homo sapiens potassium voltage-gated... 49 2e-05 AL035406-5|CAI19887.1| 254|Homo sapiens potassium voltage-gated... 49 2e-05 AL035406-4|CAC08512.1| 367|Homo sapiens potassium voltage-gated... 49 2e-05 AL035406-3|CAI19885.1| 353|Homo sapiens potassium voltage-gated... 49 2e-05 AK131252-1|BAD18431.1| 415|Homo sapiens protein ( Homo sapiens ... 49 2e-05 AF044253-1|AAB99859.1| 353|Homo sapiens potassium channel beta ... 49 2e-05 AF029749-1|AAB84170.1| 367|Homo sapiens potassium channel beta ... 49 2e-05 CR542264-1|CAG47060.1| 353|Homo sapiens KCNAB2 protein. 47 1e-04 BC099634-1|AAH99634.1| 404|Homo sapiens potassium voltage-gated... 46 2e-04 BC096234-1|AAH96234.1| 404|Homo sapiens potassium voltage-gated... 46 2e-04 BC096232-1|AAH96232.1| 404|Homo sapiens potassium voltage-gated... 46 2e-04 AB028065-1|BAA88489.1| 67|Homo sapiens prostaglandin F synthas... 46 2e-04 AF016411-1|AAB92499.1| 404|Homo sapiens KCNA3.1B protein. 44 6e-04 AB037905-2|BAA92890.1| 45|Homo sapiens truncated aldo-keto red... 38 0.049 AF026947-1|AAC52104.1| 330|Homo sapiens aflatoxin aldehyde redu... 36 0.20 Y16675-1|CAA76347.1| 330|Homo sapiens aflatoxin B1-aldehyde red... 36 0.26 BT007347-1|AAP36011.1| 330|Homo sapiens aldo-keto reductase fam... 36 0.26 BC013996-1|AAH13996.1| 330|Homo sapiens AKR7A2 protein protein. 36 0.26 BC012171-1|AAH12171.1| 330|Homo sapiens AKR7A2 protein protein. 36 0.26 BC011586-1|AAH11586.1| 330|Homo sapiens AKR7A2 protein protein. 36 0.26 BC010852-1|AAH10852.1| 330|Homo sapiens AKR7A2 protein protein. 36 0.26 BC007352-1|AAH07352.2| 358|Homo sapiens AKR7A2 protein protein. 36 0.26 BC004111-1|AAH04111.3| 330|Homo sapiens AKR7A2 protein protein. 36 0.26 AL035413-8|CAB72321.1| 330|Homo sapiens aldo-keto reductase fam... 36 0.26 M64590-1|AAA36463.1| 1020|Homo sapiens glycine decarboxylase pro... 31 5.6 M63635-1|AAA36478.1| 1020|Homo sapiens glycine decarboxylase pro... 31 5.6 D90239-1|BAA14286.1| 1020|Homo sapiens glycine decarboxylase pre... 31 5.6 BC111995-1|AAI11996.1| 1020|Homo sapiens glycine dehydrogenase (... 31 5.6 BC111993-1|AAI11994.1| 1020|Homo sapiens glycine dehydrogenase (... 31 5.6 BC042420-1|AAH42420.2| 331|Homo sapiens aldo-keto reductase fam... 31 5.6 BC031562-1|AAH31562.1| 331|Homo sapiens aldo-keto reductase fam... 31 5.6 AL353718-2|CAH74116.1| 1036|Homo sapiens glycine dehydrogenase (... 31 5.6 AL162411-3|CAH69992.1| 1036|Homo sapiens glycine dehydrogenase (... 31 5.6 AJ271799-1|CAC81076.1| 331|Homo sapiens aflatoxin B1 aldehyde r... 31 5.6 AF246134-1|AAK28443.2| 331|Homo sapiens glycine decarboxylase P... 31 5.6 AF040639-1|AAD02195.1| 331|Homo sapiens aflatoxin B1-aldehyde r... 31 5.6 BC029488-1|AAH29488.1| 294|Homo sapiens sperm acrosome associat... 31 7.4 BC025709-1|AAH25709.1| 331|Homo sapiens aldo-keto reductase fam... 31 7.4 AL136096-1|CAI19915.1| 294|Homo sapiens sperm acrosome associat... 31 7.4 AL035413-11|CAI22232.1| 331|Homo sapiens aldo-keto reductase fa... 31 7.4 AK092420-1|BAC03884.1| 357|Homo sapiens protein ( Homo sapiens ... 31 7.4 AF203447-1|AAG31422.1| 294|Homo sapiens sperm acrosome membrane... 31 7.4 >AB209017-1|BAD92254.1| 286|Homo sapiens aldo-keto reductase family 1, member C2 variant protein. Length = 286 Score = 159 bits (387), Expect = 9e-39 Identities = 95/230 (41%), Positives = 136/230 (59%), Gaps = 14/230 (6%) Frame = +2 Query: 104 TSADLIVPTLQLSSGGNIPVVALGTWL-GHRPKGKVVQVTNDTEQAVIYALEAGYTHIDT 280 T D ++L+ G +PV+ GT+ PK K ++ AV A+EAG+ HID+ Sbjct: 12 TEMDSKYQCVKLNDGHFMPVLGFGTYAPAEVPKSKALE-------AVKLAIEAGFHHIDS 64 Query: 281 AYKYGIEDQVGRALTKKFSEG-LKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYV 457 A+ Y E+QVG A+ K ++G +KRE IF T+KLW++ H E V PAL +SL+NL L+YV Sbjct: 65 AHVYNNEEQVGLAIRSKIADGSVKREDIFYTSKLWSNSHRPELVRPALERSLKNLQLDYV 124 Query: 458 DLYLIHWPIAM---------FENDTLL-DNVDFLDTWRGMIDAKKLGLTKSIGISNFNQE 607 DLYLIH+P+++ EN +L D VD TW M K GL KSIG+SNFN Sbjct: 125 DLYLIHFPVSVKPGEEVIPKDENGKILFDTVDLCATWEAMEKCKDAGLAKSIGVSNFNHR 184 Query: 608 QIQRIIDS-GLE-XPSALQIELNLNLQQPELFKFCRENDIVVMAYTPFGS 751 ++ I++ GL+ P Q+E + Q +L FC+ DIV++AY+ GS Sbjct: 185 LLEMILNKPGLKYKPVCNQVECHPYFNQRKLLDFCKSKDIVLVAYSALGS 234 >U05861-1|AAA18115.1| 323|Homo sapiens hepatic dihydrodiol dehydrogenase protein. Length = 323 Score = 159 bits (386), Expect = 1e-38 Identities = 92/221 (41%), Positives = 134/221 (60%), Gaps = 14/221 (6%) Frame = +2 Query: 131 LQLSSGGNIPVVALGTWL-GHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQ 307 ++L+ G +PV+ GT+ PK K ++ T A+EAG+ HID+A+ Y E+Q Sbjct: 8 VKLNDGHFMPVLGFGTYAPAEVPKSKALEATK-------LAIEAGFRHIDSAHLYNNEEQ 60 Query: 308 VGRALTKKFSEG-LKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPI 484 VG A+ K ++G +KRE IF T+KLW + H E V PAL +SL+NL L+YVDLYLIH+P+ Sbjct: 61 VGLAIRSKIADGSVKREDIFYTSKLWCNSHRPELVRPALERSLKNLQLDYVDLYLIHFPV 120 Query: 485 AM---------FENDTLL-DNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDS- 631 ++ EN +L D VD TW + K GL KSIG+SNFN+ Q++ I++ Sbjct: 121 SVKPGEEVIPKDENGKILFDTVDLCATWEAVEKCKDAGLAKSIGVSNFNRRQLEMILNKP 180 Query: 632 GLE-XPSALQIELNLNLQQPELFKFCRENDIVVMAYTPFGS 751 GL+ P Q+E + Q +L FC+ DIV++AY+ GS Sbjct: 181 GLKYKPVCNQVECHPYFNQRKLLDFCKSKDIVLVAYSALGS 221 >U05684-1|AAA16227.1| 323|Homo sapiens dihydrodiol dehydrogenase protein. Length = 323 Score = 159 bits (386), Expect = 1e-38 Identities = 92/221 (41%), Positives = 134/221 (60%), Gaps = 14/221 (6%) Frame = +2 Query: 131 LQLSSGGNIPVVALGTWL-GHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQ 307 ++L+ G +PV+ GT+ PK K ++ T A+EAG+ HID+A+ Y E+Q Sbjct: 8 VKLNDGHFMPVLGFGTYAPAEVPKSKALEATK-------LAIEAGFRHIDSAHLYNNEEQ 60 Query: 308 VGRALTKKFSEG-LKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPI 484 VG A+ K ++G +KRE IF T+KLW + H E V PAL +SL+NL L+YVDLYLIH+P+ Sbjct: 61 VGLAIRSKIADGSVKREDIFYTSKLWCNSHRPELVRPALERSLKNLQLDYVDLYLIHFPV 120 Query: 485 AM---------FENDTLL-DNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDS- 631 ++ EN +L D VD TW + K GL KSIG+SNFN+ Q++ I++ Sbjct: 121 SVKPGEEVIPKDENGKILFDTVDLCATWEAVEKCKDAGLAKSIGVSNFNRRQLEMILNKP 180 Query: 632 GLE-XPSALQIELNLNLQQPELFKFCRENDIVVMAYTPFGS 751 GL+ P Q+E + Q +L FC+ DIV++AY+ GS Sbjct: 181 GLKYKPVCNQVECHPYFNQRKLLDFCKSKDIVLVAYSALGS 221 >M86609-1|AAB02880.1| 323|Homo sapiens dihydrodiol dehydrogenase protein. Length = 323 Score = 159 bits (386), Expect = 1e-38 Identities = 92/221 (41%), Positives = 134/221 (60%), Gaps = 14/221 (6%) Frame = +2 Query: 131 LQLSSGGNIPVVALGTWL-GHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQ 307 ++L+ G +PV+ GT+ PK K ++ T A+EAG+ HID+A+ Y E+Q Sbjct: 8 VKLNDGHFMPVLGFGTYAPAEVPKSKALEATK-------LAIEAGFRHIDSAHLYNNEEQ 60 Query: 308 VGRALTKKFSEG-LKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPI 484 VG A+ K ++G +KRE IF T+KLW + H E V PAL +SL+NL L+YVDLYLIH+P+ Sbjct: 61 VGLAIRSKIADGSVKREDIFYTSKLWCNSHRPELVRPALERSLKNLQLDYVDLYLIHFPV 120 Query: 485 AM---------FENDTLL-DNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDS- 631 ++ EN +L D VD TW + K GL KSIG+SNFN+ Q++ I++ Sbjct: 121 SVKPGEEVIPKDENGKILFDTVDLCATWEAVEKCKDAGLAKSIGVSNFNRRQLEMILNKP 180 Query: 632 GLE-XPSALQIELNLNLQQPELFKFCRENDIVVMAYTPFGS 751 GL+ P Q+E + Q +L FC+ DIV++AY+ GS Sbjct: 181 GLKYKPVCNQVECHPYFNQRKLLDFCKSKDIVLVAYSALGS 221 >BT007197-1|AAP35861.1| 323|Homo sapiens aldo-keto reductase family 1, member C1 (dihydrodiol dehydrogenase 1; 20-alpha protein. Length = 323 Score = 159 bits (386), Expect = 1e-38 Identities = 92/221 (41%), Positives = 134/221 (60%), Gaps = 14/221 (6%) Frame = +2 Query: 131 LQLSSGGNIPVVALGTWL-GHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQ 307 ++L+ G +PV+ GT+ PK K ++ T A+EAG+ HID+A+ Y E+Q Sbjct: 8 VKLNDGHFMPVLGFGTYAPAEVPKSKALEATK-------LAIEAGFRHIDSAHLYNNEEQ 60 Query: 308 VGRALTKKFSEG-LKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPI 484 VG A+ K ++G +KRE IF T+KLW + H E V PAL +SL+NL L+YVDLYLIH+P+ Sbjct: 61 VGLAIRSKIADGSVKREDIFYTSKLWCNSHRPELVRPALERSLKNLQLDYVDLYLIHFPV 120 Query: 485 AM---------FENDTLL-DNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDS- 631 ++ EN +L D VD TW + K GL KSIG+SNFN+ Q++ I++ Sbjct: 121 SVKPGEEVIPKDENGKILFDTVDLCATWEAVEKCKDAGLAKSIGVSNFNRRQLEMILNKP 180 Query: 632 GLE-XPSALQIELNLNLQQPELFKFCRENDIVVMAYTPFGS 751 GL+ P Q+E + Q +L FC+ DIV++AY+ GS Sbjct: 181 GLKYKPVCNQVECHPYFNQRKLLDFCKSKDIVLVAYSALGS 221 >BC040210-1|AAH40210.1| 323|Homo sapiens aldo-keto reductase family 1, member C1 (dihydrodiol dehydrogenase 1; 20-alpha protein. Length = 323 Score = 159 bits (386), Expect = 1e-38 Identities = 92/221 (41%), Positives = 134/221 (60%), Gaps = 14/221 (6%) Frame = +2 Query: 131 LQLSSGGNIPVVALGTWL-GHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQ 307 ++L+ G +PV+ GT+ PK K ++ T A+EAG+ HID+A+ Y E+Q Sbjct: 8 VKLNDGHFMPVLGFGTYAPAEVPKSKALEATK-------LAIEAGFRHIDSAHLYNNEEQ 60 Query: 308 VGRALTKKFSEG-LKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPI 484 VG A+ K ++G +KRE IF T+KLW + H E V PAL +SL+NL L+YVDLYLIH+P+ Sbjct: 61 VGLAIRSKIADGSVKREDIFYTSKLWCNSHRPELVRPALERSLKNLQLDYVDLYLIHFPV 120 Query: 485 AM---------FENDTLL-DNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDS- 631 ++ EN +L D VD TW + K GL KSIG+SNFN+ Q++ I++ Sbjct: 121 SVKPGEEVIPKDENGKILFDTVDLCATWEAVEKCKDAGLAKSIGVSNFNRRQLEMILNKP 180 Query: 632 GLE-XPSALQIELNLNLQQPELFKFCRENDIVVMAYTPFGS 751 GL+ P Q+E + Q +L FC+ DIV++AY+ GS Sbjct: 181 GLKYKPVCNQVECHPYFNQRKLLDFCKSKDIVLVAYSALGS 221 >BC020216-1|AAH20216.1| 323|Homo sapiens aldo-keto reductase family 1, member C1 (dihydrodiol dehydrogenase 1; 20-alpha protein. Length = 323 Score = 159 bits (386), Expect = 1e-38 Identities = 92/221 (41%), Positives = 134/221 (60%), Gaps = 14/221 (6%) Frame = +2 Query: 131 LQLSSGGNIPVVALGTWL-GHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQ 307 ++L+ G +PV+ GT+ PK K ++ T A+EAG+ HID+A+ Y E+Q Sbjct: 8 VKLNDGHFMPVLGFGTYAPAEVPKSKALEATK-------LAIEAGFRHIDSAHLYNNEEQ 60 Query: 308 VGRALTKKFSEG-LKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPI 484 VG A+ K ++G +KRE IF T+KLW + H E V PAL +SL+NL L+YVDLYLIH+P+ Sbjct: 61 VGLAIRSKIADGSVKREDIFYTSKLWCNSHRPELVRPALERSLKNLQLDYVDLYLIHFPV 120 Query: 485 AM---------FENDTLL-DNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDS- 631 ++ EN +L D VD TW + K GL KSIG+SNFN+ Q++ I++ Sbjct: 121 SVKPGEEVIPKDENGKILFDTVDLCATWEAVEKCKDAGLAKSIGVSNFNRRQLEMILNKP 180 Query: 632 GLE-XPSALQIELNLNLQQPELFKFCRENDIVVMAYTPFGS 751 GL+ P Q+E + Q +L FC+ DIV++AY+ GS Sbjct: 181 GLKYKPVCNQVECHPYFNQRKLLDFCKSKDIVLVAYSALGS 221 >BC015490-1|AAH15490.1| 323|Homo sapiens aldo-keto reductase family 1, member C1 (dihydrodiol dehydrogenase 1; 20-alpha protein. Length = 323 Score = 159 bits (386), Expect = 1e-38 Identities = 92/221 (41%), Positives = 134/221 (60%), Gaps = 14/221 (6%) Frame = +2 Query: 131 LQLSSGGNIPVVALGTWL-GHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQ 307 ++L+ G +PV+ GT+ PK K ++ T A+EAG+ HID+A+ Y E+Q Sbjct: 8 VKLNDGHFMPVLGFGTYAPAEVPKSKALEATK-------LAIEAGFRHIDSAHLYNNEEQ 60 Query: 308 VGRALTKKFSEG-LKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPI 484 VG A+ K ++G +KRE IF T+KLW + H E V PAL +SL+NL L+YVDLYLIH+P+ Sbjct: 61 VGLAIRSKIADGSVKREDIFYTSKLWCNSHRPELVRPALERSLKNLQLDYVDLYLIHFPV 120 Query: 485 AM---------FENDTLL-DNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDS- 631 ++ EN +L D VD TW + K GL KSIG+SNFN+ Q++ I++ Sbjct: 121 SVKPGEEVIPKDENGKILFDTVDLCATWEAVEKCKDAGLAKSIGVSNFNRRQLEMILNKP 180 Query: 632 GLE-XPSALQIELNLNLQQPELFKFCRENDIVVMAYTPFGS 751 GL+ P Q+E + Q +L FC+ DIV++AY+ GS Sbjct: 181 GLKYKPVCNQVECHPYFNQRKLLDFCKSKDIVLVAYSALGS 221 >AL713867-2|CAI16409.1| 323|Homo sapiens aldo-keto reductase family 1, member C1 (dihydrodiol dehydrogenase 1; 20-alpha protein. Length = 323 Score = 159 bits (386), Expect = 1e-38 Identities = 92/221 (41%), Positives = 134/221 (60%), Gaps = 14/221 (6%) Frame = +2 Query: 131 LQLSSGGNIPVVALGTWL-GHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQ 307 ++L+ G +PV+ GT+ PK K ++ T A+EAG+ HID+A+ Y E+Q Sbjct: 8 VKLNDGHFMPVLGFGTYAPAEVPKSKALEATK-------LAIEAGFRHIDSAHLYNNEEQ 60 Query: 308 VGRALTKKFSEG-LKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPI 484 VG A+ K ++G +KRE IF T+KLW + H E V PAL +SL+NL L+YVDLYLIH+P+ Sbjct: 61 VGLAIRSKIADGSVKREDIFYTSKLWCNSHRPELVRPALERSLKNLQLDYVDLYLIHFPV 120 Query: 485 AM---------FENDTLL-DNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDS- 631 ++ EN +L D VD TW + K GL KSIG+SNFN+ Q++ I++ Sbjct: 121 SVKPGEEVIPKDENGKILFDTVDLCATWEAVEKCKDAGLAKSIGVSNFNRRQLEMILNKP 180 Query: 632 GLE-XPSALQIELNLNLQQPELFKFCRENDIVVMAYTPFGS 751 GL+ P Q+E + Q +L FC+ DIV++AY+ GS Sbjct: 181 GLKYKPVCNQVECHPYFNQRKLLDFCKSKDIVLVAYSALGS 221 >AB032150-1|BAA92886.1| 323|Homo sapiens 20 alph-hydroxysteroid dehydrogenase protein. Length = 323 Score = 159 bits (386), Expect = 1e-38 Identities = 92/221 (41%), Positives = 134/221 (60%), Gaps = 14/221 (6%) Frame = +2 Query: 131 LQLSSGGNIPVVALGTWL-GHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQ 307 ++L+ G +PV+ GT+ PK K ++ T A+EAG+ HID+A+ Y E+Q Sbjct: 8 VKLNDGHFMPVLGFGTYAPAEVPKSKALEATK-------LAIEAGFRHIDSAHLYNNEEQ 60 Query: 308 VGRALTKKFSEG-LKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPI 484 VG A+ K ++G +KRE IF T+KLW + H E V PAL +SL+NL L+YVDLYLIH+P+ Sbjct: 61 VGLAIRSKIADGSVKREDIFYTSKLWCNSHRPELVRPALERSLKNLQLDYVDLYLIHFPV 120 Query: 485 AM---------FENDTLL-DNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDS- 631 ++ EN +L D VD TW + K GL KSIG+SNFN+ Q++ I++ Sbjct: 121 SVKPGEEVIPKDENGKILFDTVDLCATWEAVEKCKDAGLAKSIGVSNFNRRQLEMILNKP 180 Query: 632 GLE-XPSALQIELNLNLQQPELFKFCRENDIVVMAYTPFGS 751 GL+ P Q+E + Q +L FC+ DIV++AY+ GS Sbjct: 181 GLKYKPVCNQVECHPYFNQRKLLDFCKSKDIVLVAYSALGS 221 >AB031083-1|BAA92883.1| 323|Homo sapiens 20 alpha-hydroxysteroid dehydrogenase protein. Length = 323 Score = 159 bits (386), Expect = 1e-38 Identities = 92/221 (41%), Positives = 134/221 (60%), Gaps = 14/221 (6%) Frame = +2 Query: 131 LQLSSGGNIPVVALGTWL-GHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQ 307 ++L+ G +PV+ GT+ PK K ++ T A+EAG+ HID+A+ Y E+Q Sbjct: 8 VKLNDGHFMPVLGFGTYAPAEVPKSKALEATK-------LAIEAGFRHIDSAHLYNNEEQ 60 Query: 308 VGRALTKKFSEG-LKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPI 484 VG A+ K ++G +KRE IF T+KLW + H E V PAL +SL+NL L+YVDLYLIH+P+ Sbjct: 61 VGLAIRSKIADGSVKREDIFYTSKLWCNSHRPELVRPALERSLKNLQLDYVDLYLIHFPV 120 Query: 485 AM---------FENDTLL-DNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDS- 631 ++ EN +L D VD TW + K GL KSIG+SNFN+ Q++ I++ Sbjct: 121 SVKPGEEVIPKDENGKILFDTVDLCATWEAVEKCKDAGLAKSIGVSNFNRRQLEMILNKP 180 Query: 632 GLE-XPSALQIELNLNLQQPELFKFCRENDIVVMAYTPFGS 751 GL+ P Q+E + Q +L FC+ DIV++AY+ GS Sbjct: 181 GLKYKPVCNQVECHPYFNQRKLLDFCKSKDIVLVAYSALGS 221 >U05598-1|AAA20937.1| 323|Homo sapiens dihydrodiol dehydrogenase protein. Length = 323 Score = 159 bits (385), Expect = 2e-38 Identities = 93/221 (42%), Positives = 134/221 (60%), Gaps = 14/221 (6%) Frame = +2 Query: 131 LQLSSGGNIPVVALGTWL-GHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQ 307 ++L+ G +PV+ GT+ PK K ++ AV A+EAG+ HID+A+ Y E+Q Sbjct: 8 VKLNDGHFMPVLGFGTYAPAEVPKSKALE-------AVKLAIEAGFHHIDSAHVYNNEEQ 60 Query: 308 VGRALTKKFSEG-LKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPI 484 VG A+ K ++G +KRE IF T+KLW++ H E V PAL +SL+NL L+YVDLYLIH+P+ Sbjct: 61 VGLAIRSKIADGSVKREDIFYTSKLWSNSHRPELVRPALERSLKNLQLDYVDLYLIHFPV 120 Query: 485 AM---------FENDTLL-DNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDS- 631 ++ EN +L D VD TW M K GL KSIG+SNFN ++ I++ Sbjct: 121 SVKPGEEVIPKDENGKILFDTVDLCATWEAMEKCKDAGLAKSIGVSNFNHRLLEMILNKP 180 Query: 632 GLE-XPSALQIELNLNLQQPELFKFCRENDIVVMAYTPFGS 751 GL+ P Q+E + Q +L FC+ DIV++AY+ GS Sbjct: 181 GLKYKPVCNQVECHPYFNQRKLLDFCKSKDIVLVAYSALGS 221 >S68330-1|AAD14013.1| 323|Homo sapiens chlordecone reductase homolog protein. Length = 323 Score = 159 bits (385), Expect = 2e-38 Identities = 93/221 (42%), Positives = 134/221 (60%), Gaps = 14/221 (6%) Frame = +2 Query: 131 LQLSSGGNIPVVALGTWL-GHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQ 307 ++L+ G +PV+ GT+ PK K ++ AV A+EAG+ HID+A+ Y E+Q Sbjct: 8 VKLNDGHFMPVLGFGTYAPAEVPKSKALE-------AVKLAIEAGFHHIDSAHVYNNEEQ 60 Query: 308 VGRALTKKFSEG-LKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPI 484 VG A+ K ++G +KRE IF T+KLW++ H E V PAL +SL+NL L+YVDLYLIH+P+ Sbjct: 61 VGLAIRSKIADGSVKREDIFYTSKLWSNSHRPELVRPALERSLKNLQLDYVDLYLIHFPV 120 Query: 485 AM---------FENDTLL-DNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRII-DS 631 ++ EN +L D VD TW M K GL KSIG+SNFN ++ I+ + Sbjct: 121 SVKPGEEVIPKDENGKILFDTVDLCATWEAMEKCKDAGLAKSIGVSNFNHRLLEMILNEP 180 Query: 632 GLE-XPSALQIELNLNLQQPELFKFCRENDIVVMAYTPFGS 751 GL+ P Q+E + Q +L FC+ DIV++AY+ GS Sbjct: 181 GLKYEPVCNQVECHPYFNQRKLLDFCKSKDIVLVAYSALGS 221 >L32592-1|AAB38486.1| 323|Homo sapiens dihydrodiol dehydrogenase/bile acid-binding protein protein. Length = 323 Score = 159 bits (385), Expect = 2e-38 Identities = 93/221 (42%), Positives = 133/221 (60%), Gaps = 14/221 (6%) Frame = +2 Query: 131 LQLSSGGNIPVVALGTWL-GHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQ 307 ++L+ G +PV+ GT+ PK K ++ AV A+EAGY HID+A+ Y E+Q Sbjct: 8 VKLNDGHFMPVLGFGTYAPAEVPKSKALE-------AVKLAIEAGYHHIDSAHVYNNEEQ 60 Query: 308 VGRALTKKFSEG-LKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPI 484 VG A+ K ++G +KRE IF T+KLW++ H E V PAL +SL+NL L+Y DLYLIH+P+ Sbjct: 61 VGLAIRSKIADGSVKREDIFYTSKLWSNSHRPELVRPALERSLKNLQLDYADLYLIHFPV 120 Query: 485 AM---------FENDTLL-DNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRII-DS 631 ++ EN +L D VD TW M K GL KSIG+SNFN ++ I+ + Sbjct: 121 SVKPGEEVIPKDENGKILFDTVDLCATWEAMEKCKDAGLAKSIGVSNFNHRLLEMILNEP 180 Query: 632 GLE-XPSALQIELNLNLQQPELFKFCRENDIVVMAYTPFGS 751 GL+ P Q+E + Q +L FC+ DIV++AY+ GS Sbjct: 181 GLKYEPVCNQVECHPYFNQRKLLDFCKSKDIVLVAYSALGS 221 >BT006653-1|AAP35299.1| 323|Homo sapiens aldo-keto reductase family 1, member C2 (dihydrodiol dehydrogenase 2; bile acid protein. Length = 323 Score = 159 bits (385), Expect = 2e-38 Identities = 93/221 (42%), Positives = 134/221 (60%), Gaps = 14/221 (6%) Frame = +2 Query: 131 LQLSSGGNIPVVALGTWL-GHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQ 307 ++L+ G +PV+ GT+ PK K ++ AV A+EAG+ HID+A+ Y E+Q Sbjct: 8 VKLNDGHFMPVLGFGTYAPAEVPKSKALE-------AVKLAIEAGFHHIDSAHVYNNEEQ 60 Query: 308 VGRALTKKFSEG-LKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPI 484 VG A+ K ++G +KRE IF T+KLW++ H E V PAL +SL+NL L+YVDLYLIH+P+ Sbjct: 61 VGLAIRSKIADGSVKREDIFYTSKLWSNSHRPELVRPALERSLKNLQLDYVDLYLIHFPV 120 Query: 485 AM---------FENDTLL-DNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDS- 631 ++ EN +L D VD TW M K GL KSIG+SNFN ++ I++ Sbjct: 121 SVKPGEEVIPKDENGKILFDTVDLCATWEAMEKCKDAGLAKSIGVSNFNHRLLEMILNKP 180 Query: 632 GLE-XPSALQIELNLNLQQPELFKFCRENDIVVMAYTPFGS 751 GL+ P Q+E + Q +L FC+ DIV++AY+ GS Sbjct: 181 GLKYKPVCNQVECHPYFNQRKLLDFCKSKDIVLVAYSALGS 221 >BC063574-1|AAH63574.1| 323|Homo sapiens aldo-keto reductase family 1, member C2 (dihydrodiol dehydrogenase 2; bile acid protein. Length = 323 Score = 159 bits (385), Expect = 2e-38 Identities = 93/221 (42%), Positives = 134/221 (60%), Gaps = 14/221 (6%) Frame = +2 Query: 131 LQLSSGGNIPVVALGTWL-GHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQ 307 ++L+ G +PV+ GT+ PK K ++ AV A+EAG+ HID+A+ Y E+Q Sbjct: 8 VKLNDGHFMPVLGFGTYAPAEVPKSKALE-------AVKLAIEAGFHHIDSAHVYNNEEQ 60 Query: 308 VGRALTKKFSEG-LKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPI 484 VG A+ K ++G +KRE IF T+KLW++ H E V PAL +SL+NL L+YVDLYLIH+P+ Sbjct: 61 VGLAIRSKIADGSVKREDIFYTSKLWSNSHRPELVRPALERSLKNLQLDYVDLYLIHFPV 120 Query: 485 AM---------FENDTLL-DNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDS- 631 ++ EN +L D VD TW M K GL KSIG+SNFN ++ I++ Sbjct: 121 SVKPGEEVIPKDENGKILFDTVDLCATWEAMEKCKDAGLAKSIGVSNFNHRLLEMILNKP 180 Query: 632 GLE-XPSALQIELNLNLQQPELFKFCRENDIVVMAYTPFGS 751 GL+ P Q+E + Q +L FC+ DIV++AY+ GS Sbjct: 181 GLKYKPVCNQVECHPYFNQRKLLDFCKSKDIVLVAYSALGS 221 >BC007024-1|AAH07024.1| 323|Homo sapiens aldo-keto reductase family 1, member C2 (dihydrodiol dehydrogenase 2; bile acid protein. Length = 323 Score = 159 bits (385), Expect = 2e-38 Identities = 93/221 (42%), Positives = 134/221 (60%), Gaps = 14/221 (6%) Frame = +2 Query: 131 LQLSSGGNIPVVALGTWL-GHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQ 307 ++L+ G +PV+ GT+ PK K ++ AV A+EAG+ HID+A+ Y E+Q Sbjct: 8 VKLNDGHFMPVLGFGTYAPAEVPKSKALE-------AVKLAIEAGFHHIDSAHVYNNEEQ 60 Query: 308 VGRALTKKFSEG-LKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPI 484 VG A+ K ++G +KRE IF T+KLW++ H E V PAL +SL+NL L+YVDLYLIH+P+ Sbjct: 61 VGLAIRSKIADGSVKREDIFYTSKLWSNSHRPELVRPALERSLKNLQLDYVDLYLIHFPV 120 Query: 485 AM---------FENDTLL-DNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDS- 631 ++ EN +L D VD TW M K GL KSIG+SNFN ++ I++ Sbjct: 121 SVKPGEEVIPKDENGKILFDTVDLCATWEAMEKCKDAGLAKSIGVSNFNHRLLEMILNKP 180 Query: 632 GLE-XPSALQIELNLNLQQPELFKFCRENDIVVMAYTPFGS 751 GL+ P Q+E + Q +L FC+ DIV++AY+ GS Sbjct: 181 GLKYKPVCNQVECHPYFNQRKLLDFCKSKDIVLVAYSALGS 221 >AL713867-1|CAI16408.1| 323|Homo sapiens aldo-keto reductase family 1, member C2 (dihydrodiol dehydrogenase 2; bile acid protein. Length = 323 Score = 159 bits (385), Expect = 2e-38 Identities = 93/221 (42%), Positives = 134/221 (60%), Gaps = 14/221 (6%) Frame = +2 Query: 131 LQLSSGGNIPVVALGTWL-GHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQ 307 ++L+ G +PV+ GT+ PK K ++ AV A+EAG+ HID+A+ Y E+Q Sbjct: 8 VKLNDGHFMPVLGFGTYAPAEVPKSKALE-------AVKLAIEAGFHHIDSAHVYNNEEQ 60 Query: 308 VGRALTKKFSEG-LKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPI 484 VG A+ K ++G +KRE IF T+KLW++ H E V PAL +SL+NL L+YVDLYLIH+P+ Sbjct: 61 VGLAIRSKIADGSVKREDIFYTSKLWSNSHRPELVRPALERSLKNLQLDYVDLYLIHFPV 120 Query: 485 AM---------FENDTLL-DNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDS- 631 ++ EN +L D VD TW M K GL KSIG+SNFN ++ I++ Sbjct: 121 SVKPGEEVIPKDENGKILFDTVDLCATWEAMEKCKDAGLAKSIGVSNFNHRLLEMILNKP 180 Query: 632 GLE-XPSALQIELNLNLQQPELFKFCRENDIVVMAYTPFGS 751 GL+ P Q+E + Q +L FC+ DIV++AY+ GS Sbjct: 181 GLKYKPVCNQVECHPYFNQRKLLDFCKSKDIVLVAYSALGS 221 >AL391427-1|CAI14726.1| 323|Homo sapiens aldo-keto reductase family 1, member C2 (dihydrodiol dehydrogenase 2; bile acid protein. Length = 323 Score = 159 bits (385), Expect = 2e-38 Identities = 93/221 (42%), Positives = 134/221 (60%), Gaps = 14/221 (6%) Frame = +2 Query: 131 LQLSSGGNIPVVALGTWL-GHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQ 307 ++L+ G +PV+ GT+ PK K ++ AV A+EAG+ HID+A+ Y E+Q Sbjct: 8 VKLNDGHFMPVLGFGTYAPAEVPKSKALE-------AVKLAIEAGFHHIDSAHVYNNEEQ 60 Query: 308 VGRALTKKFSEG-LKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPI 484 VG A+ K ++G +KRE IF T+KLW++ H E V PAL +SL+NL L+YVDLYLIH+P+ Sbjct: 61 VGLAIRSKIADGSVKREDIFYTSKLWSNSHRPELVRPALERSLKNLQLDYVDLYLIHFPV 120 Query: 485 AM---------FENDTLL-DNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDS- 631 ++ EN +L D VD TW M K GL KSIG+SNFN ++ I++ Sbjct: 121 SVKPGEEVIPKDENGKILFDTVDLCATWEAMEKCKDAGLAKSIGVSNFNHRLLEMILNKP 180 Query: 632 GLE-XPSALQIELNLNLQQPELFKFCRENDIVVMAYTPFGS 751 GL+ P Q+E + Q +L FC+ DIV++AY+ GS Sbjct: 181 GLKYKPVCNQVECHPYFNQRKLLDFCKSKDIVLVAYSALGS 221 >AB032153-1|BAA92891.1| 323|Homo sapiens bile acid-binding protein protein. Length = 323 Score = 159 bits (385), Expect = 2e-38 Identities = 93/221 (42%), Positives = 134/221 (60%), Gaps = 14/221 (6%) Frame = +2 Query: 131 LQLSSGGNIPVVALGTWL-GHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQ 307 ++L+ G +PV+ GT+ PK K ++ AV A+EAG+ HID+A+ Y E+Q Sbjct: 8 VKLNDGHFMPVLGFGTYAPAEVPKSKALE-------AVKLAIEAGFHHIDSAHVYNNEEQ 60 Query: 308 VGRALTKKFSEG-LKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPI 484 VG A+ K ++G +KRE IF T+KLW++ H E V PAL +SL+NL L+YVDLYLIH+P+ Sbjct: 61 VGLAIRSKIADGSVKREDIFYTSKLWSNSHRPELVRPALERSLKNLQLDYVDLYLIHFPV 120 Query: 485 AM---------FENDTLL-DNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDS- 631 ++ EN +L D VD TW M K GL KSIG+SNFN ++ I++ Sbjct: 121 SVKPGEEVIPKDENGKILFDTVDLCATWEAMEKCKDAGLAKSIGVSNFNHRLLEMILNKP 180 Query: 632 GLE-XPSALQIELNLNLQQPELFKFCRENDIVVMAYTPFGS 751 GL+ P Q+E + Q +L FC+ DIV++AY+ GS Sbjct: 181 GLKYKPVCNQVECHPYFNQRKLLDFCKSKDIVLVAYSALGS 221 >AB031084-1|BAA92884.1| 323|Homo sapiens bile acid-binding protein protein. Length = 323 Score = 159 bits (385), Expect = 2e-38 Identities = 93/221 (42%), Positives = 134/221 (60%), Gaps = 14/221 (6%) Frame = +2 Query: 131 LQLSSGGNIPVVALGTWL-GHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQ 307 ++L+ G +PV+ GT+ PK K ++ AV A+EAG+ HID+A+ Y E+Q Sbjct: 8 VKLNDGHFMPVLGFGTYAPAEVPKSKALE-------AVKLAIEAGFHHIDSAHVYNNEEQ 60 Query: 308 VGRALTKKFSEG-LKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPI 484 VG A+ K ++G +KRE IF T+KLW++ H E V PAL +SL+NL L+YVDLYLIH+P+ Sbjct: 61 VGLAIRSKIADGSVKREDIFYTSKLWSNSHRPELVRPALERSLKNLQLDYVDLYLIHFPV 120 Query: 485 AM---------FENDTLL-DNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDS- 631 ++ EN +L D VD TW M K GL KSIG+SNFN ++ I++ Sbjct: 121 SVKPGEEVIPKDENGKILFDTVDLCATWEAMEKCKDAGLAKSIGVSNFNHRLLEMILNKP 180 Query: 632 GLE-XPSALQIELNLNLQQPELFKFCRENDIVVMAYTPFGS 751 GL+ P Q+E + Q +L FC+ DIV++AY+ GS Sbjct: 181 GLKYKPVCNQVECHPYFNQRKLLDFCKSKDIVLVAYSALGS 221 >AB021654-1|BAA36169.1| 323|Homo sapiens DD2/bile acid-binding protein/AKR1C2/3alpha-hydroxysteroid dehydrogenase type 3 protein. Length = 323 Score = 159 bits (385), Expect = 2e-38 Identities = 93/221 (42%), Positives = 134/221 (60%), Gaps = 14/221 (6%) Frame = +2 Query: 131 LQLSSGGNIPVVALGTWL-GHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQ 307 ++L+ G +PV+ GT+ PK K ++ AV A+EAG+ HID+A+ Y E+Q Sbjct: 8 VKLNDGHFMPVLGFGTYAPAEVPKSKALE-------AVKLAIEAGFHHIDSAHVYNNEEQ 60 Query: 308 VGRALTKKFSEG-LKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPI 484 VG A+ K ++G +KRE IF T+KLW++ H E V PAL +SL+NL L+YVDLYLIH+P+ Sbjct: 61 VGLAIRSKIADGSVKREDIFYTSKLWSNSHRPELVRPALERSLKNLQLDYVDLYLIHFPV 120 Query: 485 AM---------FENDTLL-DNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDS- 631 ++ EN +L D VD TW M K GL KSIG+SNFN ++ I++ Sbjct: 121 SVKPGEEVIPKDENGKILFDTVDLCATWEAMEKCKDAGLAKSIGVSNFNHRLLEMILNKP 180 Query: 632 GLE-XPSALQIELNLNLQQPELFKFCRENDIVVMAYTPFGS 751 GL+ P Q+E + Q +L FC+ DIV++AY+ GS Sbjct: 181 GLKYKPVCNQVECHPYFNQRKLLDFCKSKDIVLVAYSALGS 221 >CR542203-1|CAG47000.1| 316|Homo sapiens AKR1B1 protein. Length = 316 Score = 157 bits (380), Expect = 7e-38 Identities = 94/231 (40%), Positives = 137/231 (59%), Gaps = 13/231 (5%) Frame = +2 Query: 131 LQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQV 310 L L++G +P++ LGTW P G+V + AV A++ GY HID A+ Y E++V Sbjct: 5 LLLNNGAKMPILGLGTWKS--PPGQVTE-------AVKVAIDVGYRHIDCAHVYQNENEV 55 Query: 311 GRALTKKFSEGL-KRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPIA 487 G A+ +K E + KRE +FI +KLW +YHE+ V A +K+L +L L+Y+DLYLIHWPI Sbjct: 56 GVAIQEKLREQVVKREELFIVSKLWCTYHEKGLVKGACQKTLSDLKLDYLDLYLIHWPIG 115 Query: 488 ------MFEND----TLLDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDS-G 634 F D + + + LDTW M + GL K+IGISNFN Q++ I++ G Sbjct: 116 FKPGKEFFPLDESGNVVPSDTNILDTWAAMEELVDEGLVKAIGISNFNHLQVEMILNKPG 175 Query: 635 LE-XPSALQIELNLNLQQPELFKFCRENDIVVMAYTPFGSLFPSKAQPDAP 784 L+ P+ QIE + L Q +L ++C+ IVV AY+P GS A+P+ P Sbjct: 176 LKYKPAVNQIECHPYLTQEKLIQYCQSKGIVVTAYSPLGSPDRPWAKPEDP 226 >J04794-1|AAA51711.1| 325|Homo sapiens ALDR1 protein. Length = 325 Score = 156 bits (379), Expect = 9e-38 Identities = 89/228 (39%), Positives = 124/228 (54%), Gaps = 12/228 (5%) Frame = +2 Query: 137 LSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQVGR 316 L +G +P++ LGTW K + QV + AV YAL GY HID A YG E ++G Sbjct: 8 LHTGQKMPLIGLGTW-----KSEPGQV----KAAVKYALSVGYRHIDCAAIYGNEPEIGE 58 Query: 317 ALTKKFSEG--LKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPIAM 490 AL + G + RE +F+T+KLWN+ H E V PALRK+L +L LEY+DLYL+HWP A Sbjct: 59 ALKEDVGPGKAVPREELFVTSKLWNTKHHPEDVEPALRKTLADLQLEYLDLYLMHWPYAF 118 Query: 491 FENDT----------LLDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGLE 640 D D+ + +TW+ + GL +++G+SNFN QI I+ Sbjct: 119 ERGDNPFPKNADGTICYDSTHYKETWKALEALVAKGLVQALGLSNFNSRQIDDILSVASV 178 Query: 641 XPSALQIELNLNLQQPELFKFCRENDIVVMAYTPFGSLFPSKAQPDAP 784 P+ LQ+E + L Q EL C+ + V AY+P GS + PD P Sbjct: 179 RPAVLQVECHPYLAQNELIAHCQARGLEVTAYSPLGSSDRAWRDPDEP 226 >CR457010-1|CAG33291.1| 325|Homo sapiens AKR1A1 protein. Length = 325 Score = 156 bits (379), Expect = 9e-38 Identities = 89/228 (39%), Positives = 124/228 (54%), Gaps = 12/228 (5%) Frame = +2 Query: 137 LSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQVGR 316 L +G +P++ LGTW K + QV + AV YAL GY HID A YG E ++G Sbjct: 8 LHTGQKMPLIGLGTW-----KSEPGQV----KAAVKYALSVGYRHIDCAAIYGNEPEIGE 58 Query: 317 ALTKKFSEG--LKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPIAM 490 AL + G + RE +F+T+KLWN+ H E V PALRK+L +L LEY+DLYL+HWP A Sbjct: 59 ALKEDVGPGKAVPREELFVTSKLWNTKHHPEDVEPALRKTLADLQLEYLDLYLMHWPYAF 118 Query: 491 FENDT----------LLDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGLE 640 D D+ + +TW+ + GL +++G+SNFN QI I+ Sbjct: 119 ERGDNPFPKNADGTICYDSTHYKETWKALEALVAKGLVQALGLSNFNSRQIDDILSVASV 178 Query: 641 XPSALQIELNLNLQQPELFKFCRENDIVVMAYTPFGSLFPSKAQPDAP 784 P+ LQ+E + L Q EL C+ + V AY+P GS + PD P Sbjct: 179 RPAVLQVECHPYLAQNELIAHCQARGLEVTAYSPLGSSDRAWRDPDEP 226 >BT007003-1|AAP35649.1| 325|Homo sapiens aldo-keto reductase family 1, member A1 (aldehyde reductase) protein. Length = 325 Score = 156 bits (379), Expect = 9e-38 Identities = 89/228 (39%), Positives = 124/228 (54%), Gaps = 12/228 (5%) Frame = +2 Query: 137 LSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQVGR 316 L +G +P++ LGTW K + QV + AV YAL GY HID A YG E ++G Sbjct: 8 LHTGQKMPLIGLGTW-----KSEPGQV----KAAVKYALSVGYRHIDCAAIYGNEPEIGE 58 Query: 317 ALTKKFSEG--LKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPIAM 490 AL + G + RE +F+T+KLWN+ H E V PALRK+L +L LEY+DLYL+HWP A Sbjct: 59 ALKEDVGPGKAVPREELFVTSKLWNTKHHPEDVEPALRKTLADLQLEYLDLYLMHWPYAF 118 Query: 491 FENDT----------LLDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGLE 640 D D+ + +TW+ + GL +++G+SNFN QI I+ Sbjct: 119 ERGDNPFPKNADGTICYDSTHYKETWKALEALVAKGLVQALGLSNFNSRQIDDILSVASV 178 Query: 641 XPSALQIELNLNLQQPELFKFCRENDIVVMAYTPFGSLFPSKAQPDAP 784 P+ LQ+E + L Q EL C+ + V AY+P GS + PD P Sbjct: 179 RPAVLQVECHPYLAQNELIAHCQARGLEVTAYSPLGSSDRAWRDPDEP 226 >BC005394-1|AAH05394.1| 325|Homo sapiens aldo-keto reductase family 1, member A1 (aldehyde reductase) protein. Length = 325 Score = 156 bits (379), Expect = 9e-38 Identities = 89/228 (39%), Positives = 124/228 (54%), Gaps = 12/228 (5%) Frame = +2 Query: 137 LSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQVGR 316 L +G +P++ LGTW K + QV + AV YAL GY HID A YG E ++G Sbjct: 8 LHTGQKMPLIGLGTW-----KSEPGQV----KAAVKYALSVGYRHIDCAAIYGNEPEIGE 58 Query: 317 ALTKKFSEG--LKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPIAM 490 AL + G + RE +F+T+KLWN+ H E V PALRK+L +L LEY+DLYL+HWP A Sbjct: 59 ALKEDVGPGKAVPREELFVTSKLWNTKHHPEDVEPALRKTLADLQLEYLDLYLMHWPYAF 118 Query: 491 FENDT----------LLDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGLE 640 D D+ + +TW+ + GL +++G+SNFN QI I+ Sbjct: 119 ERGDNPFPKNADGTICYDSTHYKETWKALEALVAKGLVQALGLSNFNSRQIDDILSVASV 178 Query: 641 XPSALQIELNLNLQQPELFKFCRENDIVVMAYTPFGSLFPSKAQPDAP 784 P+ LQ+E + L Q EL C+ + V AY+P GS + PD P Sbjct: 179 RPAVLQVECHPYLAQNELIAHCQARGLEVTAYSPLGSSDRAWRDPDEP 226 >BC000670-1|AAH00670.1| 325|Homo sapiens aldo-keto reductase family 1, member A1 (aldehyde reductase) protein. Length = 325 Score = 156 bits (379), Expect = 9e-38 Identities = 89/228 (39%), Positives = 124/228 (54%), Gaps = 12/228 (5%) Frame = +2 Query: 137 LSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQVGR 316 L +G +P++ LGTW K + QV + AV YAL GY HID A YG E ++G Sbjct: 8 LHTGQKMPLIGLGTW-----KSEPGQV----KAAVKYALSVGYRHIDCAAIYGNEPEIGE 58 Query: 317 ALTKKFSEG--LKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPIAM 490 AL + G + RE +F+T+KLWN+ H E V PALRK+L +L LEY+DLYL+HWP A Sbjct: 59 ALKEDVGPGKAVPREELFVTSKLWNTKHHPEDVEPALRKTLADLQLEYLDLYLMHWPYAF 118 Query: 491 FENDT----------LLDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGLE 640 D D+ + +TW+ + GL +++G+SNFN QI I+ Sbjct: 119 ERGDNPFPKNADGTICYDSTHYKETWKALEALVAKGLVQALGLSNFNSRQIDDILSVASV 178 Query: 641 XPSALQIELNLNLQQPELFKFCRENDIVVMAYTPFGSLFPSKAQPDAP 784 P+ LQ+E + L Q EL C+ + V AY+P GS + PD P Sbjct: 179 RPAVLQVECHPYLAQNELIAHCQARGLEVTAYSPLGSSDRAWRDPDEP 226 >AL355480-3|CAI22459.1| 325|Homo sapiens aldo-keto reductase family 1, member A1 (aldehydetase, 1 protein. Length = 325 Score = 156 bits (379), Expect = 9e-38 Identities = 89/228 (39%), Positives = 124/228 (54%), Gaps = 12/228 (5%) Frame = +2 Query: 137 LSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQVGR 316 L +G +P++ LGTW K + QV + AV YAL GY HID A YG E ++G Sbjct: 8 LHTGQKMPLIGLGTW-----KSEPGQV----KAAVKYALSVGYRHIDCAAIYGNEPEIGE 58 Query: 317 ALTKKFSEG--LKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPIAM 490 AL + G + RE +F+T+KLWN+ H E V PALRK+L +L LEY+DLYL+HWP A Sbjct: 59 ALKEDVGPGKAVPREELFVTSKLWNTKHHPEDVEPALRKTLADLQLEYLDLYLMHWPYAF 118 Query: 491 FENDT----------LLDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGLE 640 D D+ + +TW+ + GL +++G+SNFN QI I+ Sbjct: 119 ERGDNPFPKNADGTICYDSTHYKETWKALEALVAKGLVQALGLSNFNSRQIDDILSVASV 178 Query: 641 XPSALQIELNLNLQQPELFKFCRENDIVVMAYTPFGSLFPSKAQPDAP 784 P+ LQ+E + L Q EL C+ + V AY+P GS + PD P Sbjct: 179 RPAVLQVECHPYLAQNELIAHCQARGLEVTAYSPLGSSDRAWRDPDEP 226 >AF112485-1|AAF01260.1| 325|Homo sapiens aldehyde reductase protein. Length = 325 Score = 156 bits (379), Expect = 9e-38 Identities = 89/228 (39%), Positives = 124/228 (54%), Gaps = 12/228 (5%) Frame = +2 Query: 137 LSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQVGR 316 L +G +P++ LGTW K + QV + AV YAL GY HID A YG E ++G Sbjct: 8 LHTGQKMPLIGLGTW-----KSEPGQV----KAAVKYALSVGYRHIDCAAIYGNEPEIGE 58 Query: 317 ALTKKFSEG--LKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPIAM 490 AL + G + RE +F+T+KLWN+ H E V PALRK+L +L LEY+DLYL+HWP A Sbjct: 59 ALKEDVGPGKAVPREELFVTSKLWNTKHHPEDVEPALRKTLADLQLEYLDLYLMHWPYAF 118 Query: 491 FENDT----------LLDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGLE 640 D D+ + +TW+ + GL +++G+SNFN QI I+ Sbjct: 119 ERGDNPFPKNADGTICYDSTHYKETWKALEALVAKGLVQALGLSNFNSRQIDDILSVASV 178 Query: 641 XPSALQIELNLNLQQPELFKFCRENDIVVMAYTPFGSLFPSKAQPDAP 784 P+ LQ+E + L Q EL C+ + V AY+P GS + PD P Sbjct: 179 RPAVLQVECHPYLAQNELIAHCQARGLEVTAYSPLGSSDRAWRDPDEP 226 >AF036683-1|AAB92369.1| 325|Homo sapiens aldehyde reductase protein. Length = 325 Score = 156 bits (379), Expect = 9e-38 Identities = 89/228 (39%), Positives = 124/228 (54%), Gaps = 12/228 (5%) Frame = +2 Query: 137 LSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQVGR 316 L +G +P++ LGTW K + QV + AV YAL GY HID A YG E ++G Sbjct: 8 LHTGQKMPLIGLGTW-----KSEPGQV----KAAVKYALSVGYRHIDCAAIYGNEPEIGE 58 Query: 317 ALTKKFSEG--LKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPIAM 490 AL + G + RE +F+T+KLWN+ H E V PALRK+L +L LEY+DLYL+HWP A Sbjct: 59 ALKEDVGPGKAVPREELFVTSKLWNTKHHPEDVEPALRKTLADLQLEYLDLYLMHWPYAF 118 Query: 491 FENDT----------LLDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGLE 640 D D+ + +TW+ + GL +++G+SNFN QI I+ Sbjct: 119 ERGDNPFPKNADGTICYDSTHYKETWKALEALVAKGLVQALGLSNFNSRQIDDILSVASV 178 Query: 641 XPSALQIELNLNLQQPELFKFCRENDIVVMAYTPFGSLFPSKAQPDAP 784 P+ LQ+E + L Q EL C+ + V AY+P GS + PD P Sbjct: 179 RPAVLQVECHPYLAQNELIAHCQARGLEVTAYSPLGSSDRAWRDPDEP 226 >BC020744-1|AAH20744.1| 323|Homo sapiens aldo-keto reductase family 1, member C4 (chlordecone reductase; 3-alpha hydroxy protein. Length = 323 Score = 156 bits (378), Expect = 1e-37 Identities = 88/221 (39%), Positives = 133/221 (60%), Gaps = 14/221 (6%) Frame = +2 Query: 131 LQLSSGGNIPVVALGTWLGHR-PKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQ 307 ++L+ G +PV+ GT+ P+ + V+VT A+EAG+ HID+AY Y E+Q Sbjct: 8 VELNDGHFMPVLGFGTYAPPEVPRNRAVEVTK-------LAIEAGFRHIDSAYLYNNEEQ 60 Query: 308 VGRALTKKFSEG-LKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPI 484 VG A+ K ++G +KRE IF T+KLW ++ + + V PAL SL+ L L+YVDLYL+H+P+ Sbjct: 61 VGLAIRSKIADGSVKREDIFYTSKLWCTFFQPQMVQPALESSLKKLQLDYVDLYLLHFPM 120 Query: 485 AMFENDT----------LLDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDS- 631 A+ +T + D VD TW M K GL KSIG+SNFN Q++ I++ Sbjct: 121 ALKPGETPLPKDENGKVIFDTVDLSATWEVMEKCKDAGLAKSIGVSNFNYRQLEMILNKP 180 Query: 632 GLE-XPSALQIELNLNLQQPELFKFCRENDIVVMAYTPFGS 751 GL+ P Q+E + L Q +L FC+ DIV++A++ G+ Sbjct: 181 GLKYKPVCNQVECHPYLNQSKLLDFCKSKDIVLVAHSALGT 221 >AB045829-1|BAA99542.1| 323|Homo sapiens 3alpha-hydroxysteroid dehydrogenase variant protein. Length = 323 Score = 155 bits (377), Expect = 2e-37 Identities = 88/221 (39%), Positives = 133/221 (60%), Gaps = 14/221 (6%) Frame = +2 Query: 131 LQLSSGGNIPVVALGTWLGHR-PKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQ 307 ++L+ G +PV+ GT+ P+ + V+VT A+EAG+ HID+AY Y E+Q Sbjct: 8 VELNDGHFMPVLGFGTYAPPEVPRNRAVEVTK-------LAIEAGFRHIDSAYLYNNEEQ 60 Query: 308 VGRALTKKFSEG-LKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPI 484 VG A+ K ++G +KRE IF T+KLW ++ + + V PAL SL+ L L+YVDLYL+H+P+ Sbjct: 61 VGLAIRSKIADGSVKREDIFYTSKLWCTFFQPQMVQPALESSLKKLQLDYVDLYLLHFPM 120 Query: 485 AMFENDT----------LLDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDS- 631 A+ +T + D VD TW M K GL KSIG+SNFN Q++ I++ Sbjct: 121 ALKPGETPLPKDENGKVIFDTVDLCATWEVMEKCKDAGLAKSIGVSNFNCRQLEMILNKP 180 Query: 632 GLE-XPSALQIELNLNLQQPELFKFCRENDIVVMAYTPFGS 751 GL+ P Q+E + L Q +L FC+ DIV++A++ G+ Sbjct: 181 GLKYKPVCNQVECHPYLNQSKLLDFCKSKDIVLVAHSALGT 221 >S68287-1|AAD14010.1| 323|Homo sapiens chlordecone reductase protein. Length = 323 Score = 155 bits (376), Expect = 2e-37 Identities = 88/221 (39%), Positives = 133/221 (60%), Gaps = 14/221 (6%) Frame = +2 Query: 131 LQLSSGGNIPVVALGTWLGHR-PKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQ 307 ++L+ G +PV+ GT+ P+ + V+VT A+EAG+ HID+AY Y E+Q Sbjct: 8 VELNDGHFMPVLGFGTYAPPEVPRNRAVEVTK-------LAIEAGFRHIDSAYLYNNEEQ 60 Query: 308 VGRALTKKFSEG-LKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPI 484 VG A+ K ++G +KRE IF T+KLW ++ + + V PAL SL+ L L+YVDLYL+H+P+ Sbjct: 61 VGLAIRSKIADGSVKREDIFYTSKLWCTFFQPQMVQPALESSLKKLQLDYVDLYLLHFPM 120 Query: 485 AMFENDT----------LLDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDS- 631 A+ +T + D VD TW M K GL KSIG+SNFN Q++ I++ Sbjct: 121 ALKPGETPLPKDENGKVIFDTVDLSATWEVMEKCKDAGLAKSIGVSNFNCRQLEMILNKP 180 Query: 632 GLE-XPSALQIELNLNLQQPELFKFCRENDIVVMAYTPFGS 751 GL+ P Q+E + L Q +L FC+ DIV++A++ G+ Sbjct: 181 GLKYKPVCNQVECHPYLNQSKLLDFCKSKDIVLVAHSALGT 221 >D26125-1|BAA05122.1| 321|Homo sapiens 3 alpha-hydroxysteroid/dihydrodiol dehydrogenase DD4 protein. Length = 321 Score = 155 bits (376), Expect = 2e-37 Identities = 88/221 (39%), Positives = 133/221 (60%), Gaps = 14/221 (6%) Frame = +2 Query: 131 LQLSSGGNIPVVALGTWLGHR-PKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQ 307 ++L+ G +PV+ GT+ P+ + V+VT A+EAG+ HID+AY Y E+Q Sbjct: 6 VELNDGHFMPVLGFGTYAPPEVPRNRAVEVTK-------LAIEAGFRHIDSAYLYNNEEQ 58 Query: 308 VGRALTKKFSEG-LKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPI 484 VG A+ K ++G +KRE IF T+KLW ++ + + V PAL SL+ L L+YVDLYL+H+P+ Sbjct: 59 VGLAIRSKIADGSVKREDIFYTSKLWCTFFQPQMVQPALESSLKKLQLDYVDLYLLHFPM 118 Query: 485 AMFENDT----------LLDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDS- 631 A+ +T + D VD TW M K GL KSIG+SNFN Q++ I++ Sbjct: 119 ALKPGETPLPKDENGKVIFDTVDLSATWEVMEKCKDAGLAKSIGVSNFNCRQLEMILNKP 178 Query: 632 GLE-XPSALQIELNLNLQQPELFKFCRENDIVVMAYTPFGS 751 GL+ P Q+E + L Q +L FC+ DIV++A++ G+ Sbjct: 179 GLKYKPVCNQVECHPYLNQSKLLDFCKSKDIVLVAHSALGT 219 >AL355303-2|CAI14202.1| 323|Homo sapiens aldo-keto reductase family 1, member C4 (chlordecone reductase; 3-alpha hydroxy protein. Length = 323 Score = 155 bits (376), Expect = 2e-37 Identities = 88/221 (39%), Positives = 133/221 (60%), Gaps = 14/221 (6%) Frame = +2 Query: 131 LQLSSGGNIPVVALGTWLGHR-PKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQ 307 ++L+ G +PV+ GT+ P+ + V+VT A+EAG+ HID+AY Y E+Q Sbjct: 8 VELNDGHFMPVLGFGTYAPPEVPRNRAVEVTK-------LAIEAGFRHIDSAYLYNNEEQ 60 Query: 308 VGRALTKKFSEG-LKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPI 484 VG A+ K ++G +KRE IF T+KLW ++ + + V PAL SL+ L L+YVDLYL+H+P+ Sbjct: 61 VGLAIRSKIADGSVKREDIFYTSKLWCTFFQPQMVQPALESSLKKLQLDYVDLYLLHFPM 120 Query: 485 AMFENDT----------LLDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDS- 631 A+ +T + D VD TW M K GL KSIG+SNFN Q++ I++ Sbjct: 121 ALKPGETPLPKDENGKVIFDTVDLSATWEVMEKCKDAGLAKSIGVSNFNCRQLEMILNKP 180 Query: 632 GLE-XPSALQIELNLNLQQPELFKFCRENDIVVMAYTPFGS 751 GL+ P Q+E + L Q +L FC+ DIV++A++ G+ Sbjct: 181 GLKYKPVCNQVECHPYLNQSKLLDFCKSKDIVLVAHSALGT 221 >AB032163-1|BAA92893.1| 323|Homo sapiens dihydrodiol dehydrogenase 4 protein. Length = 323 Score = 155 bits (376), Expect = 2e-37 Identities = 88/221 (39%), Positives = 133/221 (60%), Gaps = 14/221 (6%) Frame = +2 Query: 131 LQLSSGGNIPVVALGTWLGHR-PKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQ 307 ++L+ G +PV+ GT+ P+ + V+VT A+EAG+ HID+AY Y E+Q Sbjct: 8 VELNDGHFMPVLGFGTYAPPEVPRNRAVEVTK-------LAIEAGFRHIDSAYLYNNEEQ 60 Query: 308 VGRALTKKFSEG-LKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPI 484 VG A+ K ++G +KRE IF T+KLW ++ + + V PAL SL+ L L+YVDLYL+H+P+ Sbjct: 61 VGLAIRSKIADGSVKREDIFYTSKLWCTFFQPQMVQPALESSLKKLQLDYVDLYLLHFPM 120 Query: 485 AMFENDT----------LLDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDS- 631 A+ +T + D VD TW M K GL KSIG+SNFN Q++ I++ Sbjct: 121 ALKPGETPLPKDENGKVIFDTVDLSATWEVMEKCKDAGLAKSIGVSNFNCRQLEMILNKP 180 Query: 632 GLE-XPSALQIELNLNLQQPELFKFCRENDIVVMAYTPFGS 751 GL+ P Q+E + L Q +L FC+ DIV++A++ G+ Sbjct: 181 GLKYKPVCNQVECHPYLNQSKLLDFCKSKDIVLVAHSALGT 221 >AB031085-1|BAA92885.1| 323|Homo sapiens dihydrodiol dehydrogenase 4 protein. Length = 323 Score = 155 bits (376), Expect = 2e-37 Identities = 88/221 (39%), Positives = 133/221 (60%), Gaps = 14/221 (6%) Frame = +2 Query: 131 LQLSSGGNIPVVALGTWLGHR-PKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQ 307 ++L+ G +PV+ GT+ P+ + V+VT A+EAG+ HID+AY Y E+Q Sbjct: 8 VELNDGHFMPVLGFGTYAPPEVPRNRAVEVTK-------LAIEAGFRHIDSAYLYNNEEQ 60 Query: 308 VGRALTKKFSEG-LKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPI 484 VG A+ K ++G +KRE IF T+KLW ++ + + V PAL SL+ L L+YVDLYL+H+P+ Sbjct: 61 VGLAIRSKIADGSVKREDIFYTSKLWCTFFQPQMVQPALESSLKKLQLDYVDLYLLHFPM 120 Query: 485 AMFENDT----------LLDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDS- 631 A+ +T + D VD TW M K GL KSIG+SNFN Q++ I++ Sbjct: 121 ALKPGETPLPKDENGKVIFDTVDLSATWEVMEKCKDAGLAKSIGVSNFNCRQLEMILNKP 180 Query: 632 GLE-XPSALQIELNLNLQQPELFKFCRENDIVVMAYTPFGS 751 GL+ P Q+E + L Q +L FC+ DIV++A++ G+ Sbjct: 181 GLKYKPVCNQVECHPYLNQSKLLDFCKSKDIVLVAHSALGT 221 >X15414-1|CAA33460.1| 316|Homo sapiens protein ( Human mRNA for aldose reductase (EC 1.1.1.2). ). Length = 316 Score = 155 bits (375), Expect = 3e-37 Identities = 93/231 (40%), Positives = 136/231 (58%), Gaps = 13/231 (5%) Frame = +2 Query: 131 LQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQV 310 L L++G +P++ LGTW P G+V + AV A++ GY HID A+ Y E++V Sbjct: 5 LLLNNGAKMPILGLGTWKS--PPGQVTE-------AVKVAIDVGYRHIDCAHVYQNENEV 55 Query: 311 GRALTKKFSEGL-KRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPIA 487 G A+ +K E + KRE +FI +KLW +YHE+ V A +K+L +L L+Y+DLYLIHWP Sbjct: 56 GVAIQEKLREQVVKREELFIVSKLWCTYHEKGLVKGACQKTLSDLKLDYLDLYLIHWPTG 115 Query: 488 ------MFEND----TLLDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDS-G 634 F D + + + LDTW M + GL K+IGISNFN Q++ I++ G Sbjct: 116 FKPGKEFFPLDESGNVVPSDTNILDTWAAMEELVDEGLVKAIGISNFNHLQVEMILNKPG 175 Query: 635 LE-XPSALQIELNLNLQQPELFKFCRENDIVVMAYTPFGSLFPSKAQPDAP 784 L+ P+ QIE + L Q +L ++C+ IVV AY+P GS A+P+ P Sbjct: 176 LKYKPAVNQIECHPYLTQEKLIQYCQSKGIVVTAYSPLGSPDRPWAKPEDP 226 >M59783-1|AAA51712.1| 316|Homo sapiens aldose reductase protein. Length = 316 Score = 155 bits (375), Expect = 3e-37 Identities = 93/231 (40%), Positives = 136/231 (58%), Gaps = 13/231 (5%) Frame = +2 Query: 131 LQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQV 310 L L++G +P++ LGTW P G+V + AV A++ GY HID A+ Y E++V Sbjct: 5 LLLNNGAKMPILGLGTWKS--PPGQVTE-------AVKVAIDVGYRHIDCAHVYQNENEV 55 Query: 311 GRALTKKFSEGL-KRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPIA 487 G A+ +K E + KRE +FI +KLW +YHE+ V A +K+L +L L+Y+DLYLIHWP Sbjct: 56 GVAIQEKLREQVVKREELFIVSKLWCTYHEKGLVKGACQKTLSDLKLDYLDLYLIHWPTG 115 Query: 488 ------MFEND----TLLDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDS-G 634 F D + + + LDTW M + GL K+IGISNFN Q++ I++ G Sbjct: 116 FKPGKEFFPLDESGNVVPSDTNILDTWAAMEELVDEGLVKAIGISNFNHLQVEMILNKPG 175 Query: 635 LE-XPSALQIELNLNLQQPELFKFCRENDIVVMAYTPFGSLFPSKAQPDAP 784 L+ P+ QIE + L Q +L ++C+ IVV AY+P GS A+P+ P Sbjct: 176 LKYKPAVNQIECHPYLTQEKLIQYCQSKGIVVTAYSPLGSPDRPWAKPEDP 226 >M34720-1|AAA35560.1| 316|Homo sapiens protein ( Human aldose reductase mRNA, complete cds. ). Length = 316 Score = 155 bits (375), Expect = 3e-37 Identities = 93/231 (40%), Positives = 136/231 (58%), Gaps = 13/231 (5%) Frame = +2 Query: 131 LQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQV 310 L L++G +P++ LGTW P G+V + AV A++ GY HID A+ Y E++V Sbjct: 5 LLLNNGAKMPILGLGTWKS--PPGQVTE-------AVKVAIDVGYRHIDCAHVYQNENEV 55 Query: 311 GRALTKKFSEGL-KRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPIA 487 G A+ +K E + KRE +FI +KLW +YHE+ V A +K+L +L L+Y+DLYLIHWP Sbjct: 56 GVAIQEKLREQVVKREELFIVSKLWCTYHEKGLVKGACQKTLSDLKLDYLDLYLIHWPTG 115 Query: 488 ------MFEND----TLLDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDS-G 634 F D + + + LDTW M + GL K+IGISNFN Q++ I++ G Sbjct: 116 FKPGKEFFPLDESGNVVPSDTNILDTWAAMEELVDEGLVKAIGISNFNHLQVEMILNKPG 175 Query: 635 LE-XPSALQIELNLNLQQPELFKFCRENDIVVMAYTPFGSLFPSKAQPDAP 784 L+ P+ QIE + L Q +L ++C+ IVV AY+P GS A+P+ P Sbjct: 176 LKYKPAVNQIECHPYLTQEKLIQYCQSKGIVVTAYSPLGSPDRPWAKPEDP 226 >J05474-1|AAA51715.1| 316|Homo sapiens aldose reductase protein. Length = 316 Score = 155 bits (375), Expect = 3e-37 Identities = 93/231 (40%), Positives = 136/231 (58%), Gaps = 13/231 (5%) Frame = +2 Query: 131 LQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQV 310 L L++G +P++ LGTW P G+V + AV A++ GY HID A+ Y E++V Sbjct: 5 LLLNNGAKMPILGLGTWKS--PPGQVTE-------AVKVAIDVGYRHIDCAHVYQNENEV 55 Query: 311 GRALTKKFSEGL-KRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPIA 487 G A+ +K E + KRE +FI +KLW +YHE+ V A +K+L +L L+Y+DLYLIHWP Sbjct: 56 GVAIQEKLREQVVKREELFIVSKLWCTYHEKGLVKGACQKTLSDLKLDYLDLYLIHWPTG 115 Query: 488 ------MFEND----TLLDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDS-G 634 F D + + + LDTW M + GL K+IGISNFN Q++ I++ G Sbjct: 116 FKPGKEFFPLDESGNVVPSDTNILDTWAAMEELVDEGLVKAIGISNFNHLQVEMILNKPG 175 Query: 635 LE-XPSALQIELNLNLQQPELFKFCRENDIVVMAYTPFGSLFPSKAQPDAP 784 L+ P+ QIE + L Q +L ++C+ IVV AY+P GS A+P+ P Sbjct: 176 LKYKPAVNQIECHPYLTQEKLIQYCQSKGIVVTAYSPLGSPDRPWAKPEDP 226 >J04795-1|AAA51713.1| 316|Homo sapiens ALDR1 protein. Length = 316 Score = 155 bits (375), Expect = 3e-37 Identities = 93/231 (40%), Positives = 136/231 (58%), Gaps = 13/231 (5%) Frame = +2 Query: 131 LQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQV 310 L L++G +P++ LGTW P G+V + AV A++ GY HID A+ Y E++V Sbjct: 5 LLLNNGAKMPILGLGTWKS--PPGQVTE-------AVKVAIDVGYRHIDCAHVYQNENEV 55 Query: 311 GRALTKKFSEGL-KRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPIA 487 G A+ +K E + KRE +FI +KLW +YHE+ V A +K+L +L L+Y+DLYLIHWP Sbjct: 56 GVAIQEKLREQVVKREELFIVSKLWCTYHEKGLVKGACQKTLSDLKLDYLDLYLIHWPTG 115 Query: 488 ------MFEND----TLLDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDS-G 634 F D + + + LDTW M + GL K+IGISNFN Q++ I++ G Sbjct: 116 FKPGKEFFPLDESGNVVPSDTNILDTWAAMEELVDEGLVKAIGISNFNHLQVEMILNKPG 175 Query: 635 LE-XPSALQIELNLNLQQPELFKFCRENDIVVMAYTPFGSLFPSKAQPDAP 784 L+ P+ QIE + L Q +L ++C+ IVV AY+P GS A+P+ P Sbjct: 176 LKYKPAVNQIECHPYLTQEKLIQYCQSKGIVVTAYSPLGSPDRPWAKPEDP 226 >D17793-1|BAA04619.2| 325|Homo sapiens KIAA0119 protein. Length = 325 Score = 155 bits (375), Expect = 3e-37 Identities = 90/233 (38%), Positives = 136/233 (58%), Gaps = 15/233 (6%) Frame = +2 Query: 131 LQLSSGGNIPVVALGTWLGHR-PKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQ 307 ++L+ G +PV+ GT+ P+ K ++VT A+EAG+ HID+A+ Y E+Q Sbjct: 10 VKLNDGHFMPVLGFGTYAPPEVPRSKALEVTK-------LAIEAGFRHIDSAHLYNNEEQ 62 Query: 308 VGRALTKKFSEG-LKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPI 484 VG A+ K ++G +KRE IF T+KLW+++H E V PAL SL+ L+YVDLYLIH P+ Sbjct: 63 VGLAIRSKIADGSVKREDIFYTSKLWSTFHRPELVRPALENSLKKAQLDYVDLYLIHSPM 122 Query: 485 AMFENDTL----------LDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDS- 631 ++ + L D VD TW M K GL KSIG+SNFN+ Q++ I++ Sbjct: 123 SLKPGEELSPTDENGKVIFDIVDLCTTWEAMEKCKDAGLAKSIGVSNFNRRQLEMILNKP 182 Query: 632 GLE-XPSALQIELNLNLQQPELFKFCRENDIVVMAYTPFGSLFPSK-AQPDAP 784 GL+ P Q+E + + +L FC+ DIV++AY+ GS + P++P Sbjct: 183 GLKYKPVCNQVECHPYFNRSKLLDFCKSKDIVLVAYSALGSQRDKRWVDPNSP 235 >BT019859-1|AAV38662.1| 316|Homo sapiens aldo-keto reductase family 1, member B1 (aldose reductase) protein. Length = 316 Score = 155 bits (375), Expect = 3e-37 Identities = 93/231 (40%), Positives = 136/231 (58%), Gaps = 13/231 (5%) Frame = +2 Query: 131 LQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQV 310 L L++G +P++ LGTW P G+V + AV A++ GY HID A+ Y E++V Sbjct: 5 LLLNNGAKMPILGLGTWKS--PPGQVTE-------AVKVAIDVGYRHIDCAHVYQNENEV 55 Query: 311 GRALTKKFSEGL-KRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPIA 487 G A+ +K E + KRE +FI +KLW +YHE+ V A +K+L +L L+Y+DLYLIHWP Sbjct: 56 GVAIQEKLREQVVKREELFIVSKLWCTYHEKGLVKGACQKTLSDLKLDYLDLYLIHWPTG 115 Query: 488 ------MFEND----TLLDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDS-G 634 F D + + + LDTW M + GL K+IGISNFN Q++ I++ G Sbjct: 116 FKPGKEFFPLDESGNVVPSDTNILDTWAAMEELVDEGLVKAIGISNFNHLQVEMILNKPG 175 Query: 635 LE-XPSALQIELNLNLQQPELFKFCRENDIVVMAYTPFGSLFPSKAQPDAP 784 L+ P+ QIE + L Q +L ++C+ IVV AY+P GS A+P+ P Sbjct: 176 LKYKPAVNQIECHPYLTQEKLIQYCQSKGIVVTAYSPLGSPDRPWAKPEDP 226 >BT007286-1|AAP35950.1| 323|Homo sapiens aldo-keto reductase family 1, member C3 (3-alpha hydroxysteroid dehydrogenase, protein. Length = 323 Score = 155 bits (375), Expect = 3e-37 Identities = 90/233 (38%), Positives = 136/233 (58%), Gaps = 15/233 (6%) Frame = +2 Query: 131 LQLSSGGNIPVVALGTWLGHR-PKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQ 307 ++L+ G +PV+ GT+ P+ K ++VT A+EAG+ HID+A+ Y E+Q Sbjct: 8 VKLNDGHFMPVLGFGTYAPPEVPRSKALEVTK-------LAIEAGFRHIDSAHLYNNEEQ 60 Query: 308 VGRALTKKFSEG-LKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPI 484 VG A+ K ++G +KRE IF T+KLW+++H E V PAL SL+ L+YVDLYLIH P+ Sbjct: 61 VGLAIRSKIADGSVKREDIFYTSKLWSTFHRPELVRPALENSLKKAQLDYVDLYLIHSPM 120 Query: 485 AMFENDTL----------LDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDS- 631 ++ + L D VD TW M K GL KSIG+SNFN+ Q++ I++ Sbjct: 121 SLKPGEELSPTDENGKVIFDIVDLCTTWEAMEKCKDAGLAKSIGVSNFNRRQLEMILNKP 180 Query: 632 GLE-XPSALQIELNLNLQQPELFKFCRENDIVVMAYTPFGSLFPSK-AQPDAP 784 GL+ P Q+E + + +L FC+ DIV++AY+ GS + P++P Sbjct: 181 GLKYKPVCNQVECHPYFNRSKLLDFCKSKDIVLVAYSALGSQRDKRWVDPNSP 233 >BC019230-1|AAH19230.1| 323|Homo sapiens aldo-keto reductase family 1, member C3 (3-alpha hydroxysteroid dehydrogenase, protein. Length = 323 Score = 155 bits (375), Expect = 3e-37 Identities = 90/233 (38%), Positives = 136/233 (58%), Gaps = 15/233 (6%) Frame = +2 Query: 131 LQLSSGGNIPVVALGTWLGHR-PKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQ 307 ++L+ G +PV+ GT+ P+ K ++VT A+EAG+ HID+A+ Y E+Q Sbjct: 8 VKLNDGHFMPVLGFGTYAPPEVPRSKALEVTK-------LAIEAGFRHIDSAHLYNNEEQ 60 Query: 308 VGRALTKKFSEG-LKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPI 484 VG A+ K ++G +KRE IF T+KLW+++H E V PAL SL+ L+YVDLYLIH P+ Sbjct: 61 VGLAIRSKIADGSVKREDIFYTSKLWSTFHRPELVRPALENSLKKAQLDYVDLYLIHSPM 120 Query: 485 AMFENDTL----------LDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDS- 631 ++ + L D VD TW M K GL KSIG+SNFN+ Q++ I++ Sbjct: 121 SLKPGEELSPTDENGKVIFDIVDLCTTWEAMEKCKDAGLAKSIGVSNFNRRQLEMILNKP 180 Query: 632 GLE-XPSALQIELNLNLQQPELFKFCRENDIVVMAYTPFGSLFPSK-AQPDAP 784 GL+ P Q+E + + +L FC+ DIV++AY+ GS + P++P Sbjct: 181 GLKYKPVCNQVECHPYFNRSKLLDFCKSKDIVLVAYSALGSQRDKRWVDPNSP 233 >BC010391-1|AAH10391.1| 316|Homo sapiens aldo-keto reductase family 1, member B1 (aldose reductase) protein. Length = 316 Score = 155 bits (375), Expect = 3e-37 Identities = 93/231 (40%), Positives = 136/231 (58%), Gaps = 13/231 (5%) Frame = +2 Query: 131 LQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQV 310 L L++G +P++ LGTW P G+V + AV A++ GY HID A+ Y E++V Sbjct: 5 LLLNNGAKMPILGLGTWKS--PPGQVTE-------AVKVAIDVGYRHIDCAHVYQNENEV 55 Query: 311 GRALTKKFSEGL-KRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPIA 487 G A+ +K E + KRE +FI +KLW +YHE+ V A +K+L +L L+Y+DLYLIHWP Sbjct: 56 GVAIQEKLREQVVKREELFIVSKLWCTYHEKGLVKGACQKTLSDLKLDYLDLYLIHWPTG 115 Query: 488 ------MFEND----TLLDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDS-G 634 F D + + + LDTW M + GL K+IGISNFN Q++ I++ G Sbjct: 116 FKPGKEFFPLDESGNVVPSDTNILDTWAAMEELVDEGLVKAIGISNFNHLQVEMILNKPG 175 Query: 635 LE-XPSALQIELNLNLQQPELFKFCRENDIVVMAYTPFGSLFPSKAQPDAP 784 L+ P+ QIE + L Q +L ++C+ IVV AY+P GS A+P+ P Sbjct: 176 LKYKPAVNQIECHPYLTQEKLIQYCQSKGIVVTAYSPLGSPDRPWAKPEDP 226 >BC001479-1|AAH01479.1| 323|Homo sapiens aldo-keto reductase family 1, member C3 (3-alpha hydroxysteroid dehydrogenase, protein. Length = 323 Score = 155 bits (375), Expect = 3e-37 Identities = 90/233 (38%), Positives = 136/233 (58%), Gaps = 15/233 (6%) Frame = +2 Query: 131 LQLSSGGNIPVVALGTWLGHR-PKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQ 307 ++L+ G +PV+ GT+ P+ K ++VT A+EAG+ HID+A+ Y E+Q Sbjct: 8 VKLNDGHFMPVLGFGTYAPPEVPRSKALEVTK-------LAIEAGFRHIDSAHLYNNEEQ 60 Query: 308 VGRALTKKFSEG-LKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPI 484 VG A+ K ++G +KRE IF T+KLW+++H E V PAL SL+ L+YVDLYLIH P+ Sbjct: 61 VGLAIRSKIADGSVKREDIFYTSKLWSTFHRPELVRPALENSLKKAQLDYVDLYLIHSPM 120 Query: 485 AMFENDTL----------LDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDS- 631 ++ + L D VD TW M K GL KSIG+SNFN+ Q++ I++ Sbjct: 121 SLKPGEELSPTDENGKVIFDIVDLCTTWEAMEKCKDAGLAKSIGVSNFNRRQLEMILNKP 180 Query: 632 GLE-XPSALQIELNLNLQQPELFKFCRENDIVVMAYTPFGSLFPSK-AQPDAP 784 GL+ P Q+E + + +L FC+ DIV++AY+ GS + P++P Sbjct: 181 GLKYKPVCNQVECHPYFNRSKLLDFCKSKDIVLVAYSALGSQRDKRWVDPNSP 233 >BC000260-1|AAH00260.1| 316|Homo sapiens aldo-keto reductase family 1, member B1 (aldose reductase) protein. Length = 316 Score = 155 bits (375), Expect = 3e-37 Identities = 93/231 (40%), Positives = 136/231 (58%), Gaps = 13/231 (5%) Frame = +2 Query: 131 LQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQV 310 L L++G +P++ LGTW P G+V + AV A++ GY HID A+ Y E++V Sbjct: 5 LLLNNGAKMPILGLGTWKS--PPGQVTE-------AVKVAIDVGYRHIDCAHVYQNENEV 55 Query: 311 GRALTKKFSEGL-KRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPIA 487 G A+ +K E + KRE +FI +KLW +YHE+ V A +K+L +L L+Y+DLYLIHWP Sbjct: 56 GVAIQEKLREQVVKREELFIVSKLWCTYHEKGLVKGACQKTLSDLKLDYLDLYLIHWPTG 115 Query: 488 ------MFEND----TLLDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDS-G 634 F D + + + LDTW M + GL K+IGISNFN Q++ I++ G Sbjct: 116 FKPGKEFFPLDESGNVVPSDTNILDTWAAMEELVDEGLVKAIGISNFNHLQVEMILNKPG 175 Query: 635 LE-XPSALQIELNLNLQQPELFKFCRENDIVVMAYTPFGSLFPSKAQPDAP 784 L+ P+ QIE + L Q +L ++C+ IVV AY+P GS A+P+ P Sbjct: 176 LKYKPAVNQIECHPYLTQEKLIQYCQSKGIVVTAYSPLGSPDRPWAKPEDP 226 >AL391427-4|CAI14729.1| 323|Homo sapiens aldo-keto reductase family 1, member C3 (3-alpha hydroxysteroid dehydrogenase, protein. Length = 323 Score = 155 bits (375), Expect = 3e-37 Identities = 90/233 (38%), Positives = 136/233 (58%), Gaps = 15/233 (6%) Frame = +2 Query: 131 LQLSSGGNIPVVALGTWLGHR-PKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQ 307 ++L+ G +PV+ GT+ P+ K ++VT A+EAG+ HID+A+ Y E+Q Sbjct: 8 VKLNDGHFMPVLGFGTYAPPEVPRSKALEVTK-------LAIEAGFRHIDSAHLYNNEEQ 60 Query: 308 VGRALTKKFSEG-LKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPI 484 VG A+ K ++G +KRE IF T+KLW+++H E V PAL SL+ L+YVDLYLIH P+ Sbjct: 61 VGLAIRSKIADGSVKREDIFYTSKLWSTFHRPELVRPALENSLKKAQLDYVDLYLIHSPM 120 Query: 485 AMFENDTL----------LDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDS- 631 ++ + L D VD TW M K GL KSIG+SNFN+ Q++ I++ Sbjct: 121 SLKPGEELSPTDENGKVIFDIVDLCTTWEAMEKCKDAGLAKSIGVSNFNRRQLEMILNKP 180 Query: 632 GLE-XPSALQIELNLNLQQPELFKFCRENDIVVMAYTPFGSLFPSK-AQPDAP 784 GL+ P Q+E + + +L FC+ DIV++AY+ GS + P++P Sbjct: 181 GLKYKPVCNQVECHPYFNRSKLLDFCKSKDIVLVAYSALGSQRDKRWVDPNSP 233 >AF328729-1|AAN09721.1| 316|Homo sapiens CTCL tumor antigen HD-CL-07 protein. Length = 316 Score = 155 bits (375), Expect = 3e-37 Identities = 93/231 (40%), Positives = 136/231 (58%), Gaps = 13/231 (5%) Frame = +2 Query: 131 LQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQV 310 L L++G +P++ LGTW P G+V + AV A++ GY HID A+ Y E++V Sbjct: 5 LLLNNGAKMPILGLGTWKS--PPGQVTE-------AVKVAIDVGYRHIDCAHVYQNENEV 55 Query: 311 GRALTKKFSEGL-KRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPIA 487 G A+ +K E + KRE +FI +KLW +YHE+ V A +K+L +L L+Y+DLYLIHWP Sbjct: 56 GVAIQEKLREQVVKREELFIVSKLWCTYHEKGLVKGACQKTLSDLKLDYLDLYLIHWPTG 115 Query: 488 ------MFEND----TLLDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDS-G 634 F D + + + LDTW M + GL K+IGISNFN Q++ I++ G Sbjct: 116 FKPGKEFFPLDESGNVVPSDTNILDTWAAMEELVDEGLVKAIGISNFNHLQVEMILNKPG 175 Query: 635 LE-XPSALQIELNLNLQQPELFKFCRENDIVVMAYTPFGSLFPSKAQPDAP 784 L+ P+ QIE + L Q +L ++C+ IVV AY+P GS A+P+ P Sbjct: 176 LKYKPAVNQIECHPYLTQEKLIQYCQSKGIVVTAYSPLGSPDRPWAKPEDP 226 >AF032455-1|AAB88851.1| 316|Homo sapiens aldose reductase protein. Length = 316 Score = 155 bits (375), Expect = 3e-37 Identities = 93/231 (40%), Positives = 136/231 (58%), Gaps = 13/231 (5%) Frame = +2 Query: 131 LQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQV 310 L L++G +P++ LGTW P G+V + AV A++ GY HID A+ Y E++V Sbjct: 5 LLLNNGAKMPILGLGTWKS--PPGQVTE-------AVKVAIDVGYRHIDCAHVYQNENEV 55 Query: 311 GRALTKKFSEGL-KRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPIA 487 G A+ +K E + KRE +FI +KLW +YHE+ V A +K+L +L L+Y+DLYLIHWP Sbjct: 56 GVAIQEKLREQVVKREELFIVSKLWCTYHEKGLVKGACQKTLSDLKLDYLDLYLIHWPTG 115 Query: 488 ------MFEND----TLLDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDS-G 634 F D + + + LDTW M + GL K+IGISNFN Q++ I++ G Sbjct: 116 FKPGKEFFPLDESGNVVPSDTNILDTWAAMEELVDEGLVKAIGISNFNHLQVEMILNKPG 175 Query: 635 LE-XPSALQIELNLNLQQPELFKFCRENDIVVMAYTPFGSLFPSKAQPDAP 784 L+ P+ QIE + L Q +L ++C+ IVV AY+P GS A+P+ P Sbjct: 176 LKYKPAVNQIECHPYLTQEKLIQYCQSKGIVVTAYSPLGSPDRPWAKPEDP 226 >AB209796-1|BAD93033.1| 260|Homo sapiens aldo-keto reductase family 1, member B1 variant protein. Length = 260 Score = 155 bits (375), Expect = 3e-37 Identities = 93/231 (40%), Positives = 136/231 (58%), Gaps = 13/231 (5%) Frame = +2 Query: 131 LQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQV 310 L L++G +P++ LGTW P G+V + AV A++ GY HID A+ Y E++V Sbjct: 2 LLLNNGAKMPILGLGTWKS--PPGQVTE-------AVKVAIDVGYRHIDCAHVYQNENEV 52 Query: 311 GRALTKKFSEGL-KRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPIA 487 G A+ +K E + KRE +FI +KLW +YHE+ V A +K+L +L L+Y+DLYLIHWP Sbjct: 53 GVAIQEKLREQVVKREELFIVSKLWCTYHEKGLVKGACQKTLSDLKLDYLDLYLIHWPTG 112 Query: 488 ------MFEND----TLLDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDS-G 634 F D + + + LDTW M + GL K+IGISNFN Q++ I++ G Sbjct: 113 FKPGKEFFPLDESGNVVPSDTNILDTWAAMEELVDEGLVKAIGISNFNHLQVEMILNKPG 172 Query: 635 LE-XPSALQIELNLNLQQPELFKFCRENDIVVMAYTPFGSLFPSKAQPDAP 784 L+ P+ QIE + L Q +L ++C+ IVV AY+P GS A+P+ P Sbjct: 173 LKYKPAVNQIECHPYLTQEKLIQYCQSKGIVVTAYSPLGSPDRPWAKPEDP 223 >AB032157-1|BAA92892.1| 323|Homo sapiens prostaglandin F synthase protein. Length = 323 Score = 155 bits (375), Expect = 3e-37 Identities = 90/233 (38%), Positives = 136/233 (58%), Gaps = 15/233 (6%) Frame = +2 Query: 131 LQLSSGGNIPVVALGTWLGHR-PKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQ 307 ++L+ G +PV+ GT+ P+ K ++VT A+EAG+ HID+A+ Y E+Q Sbjct: 8 VKLNDGHFMPVLGFGTYAPPEVPRSKALEVTK-------LAIEAGFRHIDSAHLYNNEEQ 60 Query: 308 VGRALTKKFSEG-LKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPI 484 VG A+ K ++G +KRE IF T+KLW+++H E V PAL SL+ L+YVDLYLIH P+ Sbjct: 61 VGLAIRSKIADGSVKREDIFYTSKLWSTFHRPELVRPALENSLKKAQLDYVDLYLIHSPM 120 Query: 485 AMFENDTL----------LDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDS- 631 ++ + L D VD TW M K GL KSIG+SNFN+ Q++ I++ Sbjct: 121 SLKPGEELSPTDENGKVIFDIVDLCTTWEAMEKCKDAGLAKSIGVSNFNRRQLEMILNKP 180 Query: 632 GLE-XPSALQIELNLNLQQPELFKFCRENDIVVMAYTPFGSLFPSK-AQPDAP 784 GL+ P Q+E + + +L FC+ DIV++AY+ GS + P++P Sbjct: 181 GLKYKPVCNQVECHPYFNRSKLLDFCKSKDIVLVAYSALGSQRDKRWVDPNSP 233 >AB018580-1|BAA88488.1| 323|Homo sapiens hluPGFS protein. Length = 323 Score = 155 bits (375), Expect = 3e-37 Identities = 90/233 (38%), Positives = 136/233 (58%), Gaps = 15/233 (6%) Frame = +2 Query: 131 LQLSSGGNIPVVALGTWLGHR-PKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQ 307 ++L+ G +PV+ GT+ P+ K ++VT A+EAG+ HID+A+ Y E+Q Sbjct: 8 VKLNDGHFMPVLGFGTYAPPEVPRSKALEVTK-------LAIEAGFRHIDSAHLYNNEEQ 60 Query: 308 VGRALTKKFSEG-LKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPI 484 VG A+ K ++G +KRE IF T+KLW+++H E V PAL SL+ L+YVDLYLIH P+ Sbjct: 61 VGLAIRSKIADGSVKREDIFYTSKLWSTFHRPELVRPALENSLKKAQLDYVDLYLIHSPM 120 Query: 485 AMFENDTL----------LDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDS- 631 ++ + L D VD TW M K GL KSIG+SNFN+ Q++ I++ Sbjct: 121 SLKPGEELSPTDENGKVIFDIVDLCTTWEAMEKCKDAGLAKSIGVSNFNRRQLEMILNKP 180 Query: 632 GLE-XPSALQIELNLNLQQPELFKFCRENDIVVMAYTPFGSLFPSK-AQPDAP 784 GL+ P Q+E + + +L FC+ DIV++AY+ GS + P++P Sbjct: 181 GLKYKPVCNQVECHPYFNRSKLLDFCKSKDIVLVAYSALGSQRDKRWVDPNSP 233 >U37100-1|AAC17469.1| 316|Homo sapiens aldose reductase-like peptide protein. Length = 316 Score = 154 bits (374), Expect = 4e-37 Identities = 90/231 (38%), Positives = 131/231 (56%), Gaps = 13/231 (5%) Frame = +2 Query: 131 LQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQV 310 ++LS+ +P+V LGTW P GKV ++AV A++AGY HID AY Y E +V Sbjct: 5 VELSTKAKMPIVGLGTWKS--PLGKV-------KEAVKVAIDAGYRHIDCAYVYQNEHEV 55 Query: 311 GRALTKKFSE-GLKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPIA 487 G A+ +K E +KRE +FI +KLW ++ ER V A K+L++L L Y+D+YLIHWP Sbjct: 56 GEAIQEKIQEKAVKREDLFIVSKLWPTFFERPLVRKAFEKTLKDLKLSYLDVYLIHWPQG 115 Query: 488 MFENDTLLDNVD----------FLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDS-G 634 D L D FLD W M + GL K++G+SNF+ QI+++++ G Sbjct: 116 FKSGDDLFPKDDKGNAIGGKATFLDAWEAMEELVDEGLVKALGVSNFSHFQIEKLLNKPG 175 Query: 635 LE-XPSALQIELNLNLQQPELFKFCRENDIVVMAYTPFGSLFPSKAQPDAP 784 L+ P Q+E + L Q +L ++C I V AY+P GS A+P+ P Sbjct: 176 LKYKPVTNQVECHPYLTQEKLIQYCHSKGITVTAYSPLGSPDRPWAKPEDP 226 >CR541801-1|CAG46600.1| 316|Homo sapiens AKR1B10 protein. Length = 316 Score = 154 bits (374), Expect = 4e-37 Identities = 90/231 (38%), Positives = 131/231 (56%), Gaps = 13/231 (5%) Frame = +2 Query: 131 LQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQV 310 ++LS+ +P+V LGTW P GKV ++AV A++AGY HID AY Y E +V Sbjct: 5 VELSTKAKMPIVGLGTWKS--PLGKV-------KEAVKVAIDAGYRHIDCAYVYQNEHEV 55 Query: 311 GRALTKKFSE-GLKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPIA 487 G A+ +K E +KRE +FI +KLW ++ ER V A K+L++L L Y+D+YLIHWP Sbjct: 56 GEAIQEKIQEKAVKREDLFIVSKLWPTFFERPLVRKAFEKTLKDLKLSYLDVYLIHWPQG 115 Query: 488 MFENDTLLDNVD----------FLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDS-G 634 D L D FLD W M + GL K++G+SNF+ QI+++++ G Sbjct: 116 FKSGDDLFPKDDKGNAIGGKATFLDAWEAMEELVDEGLVKALGVSNFSHFQIEKLLNKPG 175 Query: 635 LE-XPSALQIELNLNLQQPELFKFCRENDIVVMAYTPFGSLFPSKAQPDAP 784 L+ P Q+E + L Q +L ++C I V AY+P GS A+P+ P Sbjct: 176 LKYKPVTNQVECHPYLTQEKLIQYCHSKGITVTAYSPLGSPDRPWAKPEDP 226 >CR450351-1|CAG29347.1| 316|Homo sapiens AKR1B1 protein. Length = 316 Score = 154 bits (374), Expect = 4e-37 Identities = 93/231 (40%), Positives = 135/231 (58%), Gaps = 13/231 (5%) Frame = +2 Query: 131 LQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQV 310 L L++G +P++ LGTW P G+V + AV A++ GY HID A+ Y E++V Sbjct: 5 LLLNNGAKMPILGLGTWKS--PPGQVTE-------AVKVAIDVGYRHIDCAHVYQNENEV 55 Query: 311 GRALTKKFSEGL-KRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPIA 487 G A+ +K E + KRE +FI +KLW +YHE+ V A +K+L +L L+Y+DLYLIHWP Sbjct: 56 GVAIQEKLREQVVKREELFIVSKLWCTYHEKGLVKGACQKTLSDLKLDYLDLYLIHWPTG 115 Query: 488 ------MFEND----TLLDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDS-G 634 F D + + + LDTW M + GL K+IGISNFN Q++ I+ G Sbjct: 116 FRPGKEFFPLDESGNVVPSDTNILDTWAAMEELVDEGLVKAIGISNFNHLQVEMILSKPG 175 Query: 635 LE-XPSALQIELNLNLQQPELFKFCRENDIVVMAYTPFGSLFPSKAQPDAP 784 L+ P+ QIE + L Q +L ++C+ IVV AY+P GS A+P+ P Sbjct: 176 LKYKPAVNQIECHPYLTQEKLIQYCQSKGIVVTAYSPLGSPDRPWAKPEDP 226 >BT006794-1|AAP35440.1| 316|Homo sapiens aldo-keto reductase family 1, member B10 (aldose reductase) protein. Length = 316 Score = 154 bits (374), Expect = 4e-37 Identities = 90/231 (38%), Positives = 131/231 (56%), Gaps = 13/231 (5%) Frame = +2 Query: 131 LQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQV 310 ++LS+ +P+V LGTW P GKV ++AV A++AGY HID AY Y E +V Sbjct: 5 VELSTKAKMPIVGLGTWKS--PLGKV-------KEAVKVAIDAGYRHIDCAYVYQNEHEV 55 Query: 311 GRALTKKFSE-GLKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPIA 487 G A+ +K E +KRE +FI +KLW ++ ER V A K+L++L L Y+D+YLIHWP Sbjct: 56 GEAIQEKIQEKAVKREDLFIVSKLWPTFFERPLVRKAFEKTLKDLKLSYLDVYLIHWPQG 115 Query: 488 MFENDTLLDNVD----------FLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDS-G 634 D L D FLD W M + GL K++G+SNF+ QI+++++ G Sbjct: 116 FKSGDDLFPKDDKGNAIGGKATFLDAWEAMEELVDEGLVKALGVSNFSHFQIEKLLNKPG 175 Query: 635 LE-XPSALQIELNLNLQQPELFKFCRENDIVVMAYTPFGSLFPSKAQPDAP 784 L+ P Q+E + L Q +L ++C I V AY+P GS A+P+ P Sbjct: 176 LKYKPVTNQVECHPYLTQEKLIQYCHSKGITVTAYSPLGSPDRPWAKPEDP 226 >BC008837-1|AAH08837.1| 316|Homo sapiens aldo-keto reductase family 1, member B10 (aldose reductase) protein. Length = 316 Score = 154 bits (374), Expect = 4e-37 Identities = 90/231 (38%), Positives = 131/231 (56%), Gaps = 13/231 (5%) Frame = +2 Query: 131 LQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQV 310 ++LS+ +P+V LGTW P GKV ++AV A++AGY HID AY Y E +V Sbjct: 5 VELSTKAKMPIVGLGTWKS--PLGKV-------KEAVKVAIDAGYRHIDCAYVYQNEHEV 55 Query: 311 GRALTKKFSE-GLKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPIA 487 G A+ +K E +KRE +FI +KLW ++ ER V A K+L++L L Y+D+YLIHWP Sbjct: 56 GEAIQEKIQEKAVKREDLFIVSKLWPTFFERPLVRKAFEKTLKDLKLSYLDVYLIHWPQG 115 Query: 488 MFENDTLLDNVD----------FLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDS-G 634 D L D FLD W M + GL K++G+SNF+ QI+++++ G Sbjct: 116 FKSGDDLFPKDDKGNAIGGKATFLDAWEAMEELVDEGLVKALGVSNFSHFQIEKLLNKPG 175 Query: 635 LE-XPSALQIELNLNLQQPELFKFCRENDIVVMAYTPFGSLFPSKAQPDAP 784 L+ P Q+E + L Q +L ++C I V AY+P GS A+P+ P Sbjct: 176 LKYKPVTNQVECHPYLTQEKLIQYCHSKGITVTAYSPLGSPDRPWAKPEDP 226 >AF052577-1|AAC36465.1| 316|Homo sapiens aldo-keto reductase protein. Length = 316 Score = 154 bits (374), Expect = 4e-37 Identities = 90/231 (38%), Positives = 131/231 (56%), Gaps = 13/231 (5%) Frame = +2 Query: 131 LQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQV 310 ++LS+ +P+V LGTW P GKV ++AV A++AGY HID AY Y E +V Sbjct: 5 VELSTKAKMPIVGLGTWKS--PLGKV-------KEAVKVAIDAGYRHIDCAYVYQNEHEV 55 Query: 311 GRALTKKFSE-GLKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPIA 487 G A+ +K E +KRE +FI +KLW ++ ER V A K+L++L L Y+D+YLIHWP Sbjct: 56 GEAIQEKIQEKAVKREDLFIVSKLWPTFFERPLVRKAFEKTLKDLKLSYLDVYLIHWPQG 115 Query: 488 MFENDTLLDNVD----------FLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDS-G 634 D L D FLD W M + GL K++G+SNF+ QI+++++ G Sbjct: 116 FKSGDDLFPKDDKGNAIGGKATFLDAWEAMEELVDEGLVKALGVSNFSHFQIEKLLNKPG 175 Query: 635 LE-XPSALQIELNLNLQQPELFKFCRENDIVVMAYTPFGSLFPSKAQPDAP 784 L+ P Q+E + L Q +L ++C I V AY+P GS A+P+ P Sbjct: 176 LKYKPVTNQVECHPYLTQEKLIQYCHSKGITVTAYSPLGSPDRPWAKPEDP 226 >J05017-1|AAA51714.1| 316|Homo sapiens ALDR1 protein. Length = 316 Score = 154 bits (373), Expect = 5e-37 Identities = 92/229 (40%), Positives = 135/229 (58%), Gaps = 13/229 (5%) Frame = +2 Query: 137 LSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQVGR 316 L++G +P++ LGTW P G+V + AV A++ GY HID A+ Y E++VG Sbjct: 7 LNNGAKMPILGLGTWKS--PPGQVTE-------AVKVAIDVGYRHIDCAHVYQNENEVGV 57 Query: 317 ALTKKFSEGL-KRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPIA-- 487 A+ +K E + KRE +FI +KLW +YHE+ V A +K+L +L L+Y+DLYLIHWP Sbjct: 58 AIQEKLREQVVKREELFIVSKLWCTYHEKGLVKGACQKTLSDLKLDYLDLYLIHWPTGFK 117 Query: 488 ----MFEND----TLLDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDS-GLE 640 F D + + + LDTW M + GL K+IGISNFN Q++ I++ GL+ Sbjct: 118 PGKEFFPLDESGNVVPSDTNILDTWAAMEELVDEGLVKAIGISNFNHLQVEMILNKPGLK 177 Query: 641 -XPSALQIELNLNLQQPELFKFCRENDIVVMAYTPFGSLFPSKAQPDAP 784 P+ QIE + L Q +L ++C+ IVV AY+P GS A+P+ P Sbjct: 178 YKPAVNQIECHPYLTQEKLIQYCQSKGIVVTAYSPLGSPDRPWAKPEDP 226 >S68290-1|AAD14012.1| 320|Homo sapiens chlordecone reductase homolog protein. Length = 320 Score = 153 bits (370), Expect = 1e-36 Identities = 90/222 (40%), Positives = 132/222 (59%), Gaps = 14/222 (6%) Frame = +2 Query: 131 LQLSSGGNIPVVALGTWL-GHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQ 307 ++L+ G +PV+ GT+ PK K ++ T A+EAG+ HID+A+ Y E+Q Sbjct: 5 VKLNDGHFMPVLGFGTYAPAEVPKSKALEATK-------LAIEAGFRHIDSAHLYNNEEQ 57 Query: 308 VGRALTKKFSEG-LKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPI 484 VG A+ K ++G +KRE IF T+KLW + H E PAL +SL+NL L+YVDLYLIH+P+ Sbjct: 58 VGLAIRSKIADGSVKREDIFYTSKLWCNSHRPELDRPALERSLKNLQLDYVDLYLIHFPV 117 Query: 485 AM---------FENDTLL-DNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDS- 631 ++ EN +L D VD TW + K L KSIG+SNFN+ ++ I++ Sbjct: 118 SVKPGEEVIPKDENGKILFDTVDLCATWEAVEKCKDAELAKSIGVSNFNRSTLEMILNKP 177 Query: 632 GLE-XPSALQIELNLNLQQPELFKFCRENDIVVMAYTPFGSL 754 GL+ P Q+E + Q +L FC+ DIV++AY+ GSL Sbjct: 178 GLQVKPVCNQVECHPYFNQRKLLDFCKSKDIVLVAYSALGSL 219 >D26124-1|BAA05121.1| 306|Homo sapiens dihydrodiol dehydrogenase isoform DD1 protein. Length = 306 Score = 153 bits (370), Expect = 1e-36 Identities = 89/211 (42%), Positives = 127/211 (60%), Gaps = 14/211 (6%) Frame = +2 Query: 161 VVALGTWL-GHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQVGRALTKKFS 337 V+ GT+ PK K ++ T A+EAG+ HID+A+ Y E+QVG A+ K + Sbjct: 1 VLGFGTYAPAEVPKSKALEATK-------LAIEAGFRHIDSAHLYNNEEQVGLAIRSKIA 53 Query: 338 EG-LKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPIAM-------- 490 +G +KRE IF T+KLW + H E V PAL +SL+NL L+YVDLYLIH+P+++ Sbjct: 54 DGSVKREDIFYTSKLWCNSHRPELVRPALERSLKNLQLDYVDLYLIHFPVSVKPGEEVIP 113 Query: 491 -FENDTLL-DNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDS-GLE-XPSALQ 658 EN +L D VD TW + K GL KSIG+SNFN+ Q++ I++ GL+ P Q Sbjct: 114 KDENGKILFDTVDLCATWEAVEKCKDAGLAKSIGVSNFNRRQLEMILNKPGLKYKPVCNQ 173 Query: 659 IELNLNLQQPELFKFCRENDIVVMAYTPFGS 751 +E + Q +L FC+ DIV++AY+ GS Sbjct: 174 VECHPYFNQRKLLDFCKSKDIVLVAYSALGS 204 >S68288-1|AAD14011.1| 323|Homo sapiens chlordecone reductase homolog protein. Length = 323 Score = 152 bits (369), Expect = 1e-36 Identities = 89/233 (38%), Positives = 136/233 (58%), Gaps = 15/233 (6%) Frame = +2 Query: 131 LQLSSGGNIPVVALGTWLGHR-PKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQ 307 ++L+ G +PV+ GT+ P+ K ++VT A+EAG+ HID+A+ Y E+Q Sbjct: 8 VKLNDGHFMPVLGFGTYAPPEVPRSKALEVTK-------LAIEAGFRHIDSAHLYNNEEQ 60 Query: 308 VGRALTKKFSEG-LKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPI 484 VG A+ K ++G ++RE IF T+KLW+++H E V PAL SL+ L+YVDLYLIH P+ Sbjct: 61 VGLAIRSKIADGSVEREDIFYTSKLWSTFHRPELVRPALENSLKKAQLDYVDLYLIHSPM 120 Query: 485 AMFENDTL----------LDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDS- 631 ++ + L D VD TW M K GL KSIG+SNFN+ Q++ I++ Sbjct: 121 SLKPGEELSPTDENGKVIFDIVDLCTTWEAMEKCKDAGLAKSIGVSNFNRRQLEIILNKP 180 Query: 632 GLE-XPSALQIELNLNLQQPELFKFCRENDIVVMAYTPFGSLFPSK-AQPDAP 784 GL+ P Q+E + + +L FC+ DIV++AY+ GS + P++P Sbjct: 181 GLKYKPVCNQVECHPYFNRSKLLDFCKSKDIVLVAYSALGSQRDKRWVDPNSP 233 >M33375-1|AAA35658.1| 308|Homo sapiens protein ( Human chlordecone reductase mRNA, complete cds. ). Length = 308 Score = 151 bits (367), Expect = 3e-36 Identities = 86/213 (40%), Positives = 128/213 (60%), Gaps = 14/213 (6%) Frame = +2 Query: 155 IPVVALGTWLGHR-PKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQVGRALTKK 331 +PV+ GT+ P+ + V+VT A+EAG+ HID+AY Y E+QVG A+ K Sbjct: 1 MPVLGFGTYAPPEVPRNRAVEVTK-------LAIEAGFRHIDSAYLYNNEEQVGLAIRSK 53 Query: 332 FSEG-LKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPIAMFENDT- 505 ++G +KRE IF T+KLW ++ + + V PAL SL+ L L+YVDLYL+H+P+A+ +T Sbjct: 54 IADGSVKREDIFYTSKLWCTFFQPQMVQPALESSLKKLQLDYVDLYLLHFPMALKPGETP 113 Query: 506 ---------LLDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDS-GLE-XPSA 652 + D VD TW M K GL KSIG+SNFN Q++ I++ GL+ P Sbjct: 114 LPKDENGKVIFDTVDLSATWEVMEKCKDAGLAKSIGVSNFNCRQLEMILNKPGLKYKPVC 173 Query: 653 LQIELNLNLQQPELFKFCRENDIVVMAYTPFGS 751 Q+E + L Q +L FC+ DIV++A++ G+ Sbjct: 174 NQVECHPYLNQSKLLDFCKSKDIVLVAHSALGT 206 >L43839-1|AAB41916.1| 323|Homo sapiens 3-alpha-hydroxysteroid dehydrogenase protein. Length = 323 Score = 151 bits (367), Expect = 3e-36 Identities = 89/233 (38%), Positives = 135/233 (57%), Gaps = 15/233 (6%) Frame = +2 Query: 131 LQLSSGGNIPVVALGTWLGHR-PKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQ 307 ++L+ G +PV+ GT+ P+ K ++VT A+EAG+ HID+A+ Y E+Q Sbjct: 8 VKLNDGHFMPVLGFGTYAPPEVPRSKALEVTK-------LAIEAGFRHIDSAHLYNNEEQ 60 Query: 308 VGRALTKKFSEG-LKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPI 484 VG A+ K ++G + RE IF T+KLW+++H E V PAL SL+ L+YVDLYLIH P+ Sbjct: 61 VGLAIRSKIADGSVMREDIFYTSKLWSTFHRPELVRPALENSLKKAQLDYVDLYLIHSPM 120 Query: 485 AMFENDTL----------LDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDS- 631 ++ + L D VD TW M K GL KSIG+SNFN+ Q++ I++ Sbjct: 121 SLKPGEELSPTDENGKVIFDIVDLCTTWEAMEKCKDAGLAKSIGVSNFNRRQLEIILNKP 180 Query: 632 GLE-XPSALQIELNLNLQQPELFKFCRENDIVVMAYTPFGSLFPSK-AQPDAP 784 GL+ P Q+E + + +L FC+ DIV++AY+ GS + P++P Sbjct: 181 GLKYKPVCNQVECHPYFNRSKLLDFCKSKDIVLVAYSALGSQRDKRWVDPNSP 233 >DQ269985-1|ABB76132.1| 323|Homo sapiens type II 3a-hydroxysteroid dehydrogenase variant protein. Length = 323 Score = 151 bits (367), Expect = 3e-36 Identities = 90/233 (38%), Positives = 134/233 (57%), Gaps = 15/233 (6%) Frame = +2 Query: 131 LQLSSGGNIPVVALGTWL-GHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQ 307 ++L+ G +PV+ GT+ PK K ++ T A+EAG+ HID+A+ Y E+Q Sbjct: 8 VKLNDGHFMPVLGFGTYAPAEVPKSKALEATK-------LAIEAGFRHIDSAHLYNNEEQ 60 Query: 308 VGRALTKKFSEG-LKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPI 484 VG A+ K ++G +KRE IF T+KLW + H E V PAL +SL+ L+YVDLYLIH P+ Sbjct: 61 VGLAVRSKIADGSVKREDIFYTSKLWCNSHRPELVRPALERSLKKAQLDYVDLYLIHSPM 120 Query: 485 AMFENDTL----------LDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDS- 631 ++ + L D VD TW M K GL KSIG+SNFN+ Q++ I++ Sbjct: 121 SLKPGEELSPTDENGKVIFDIVDLCTTWEAMEKCKDAGLAKSIGVSNFNRRQLEMILNKP 180 Query: 632 GLE-XPSALQIELNLNLQQPELFKFCRENDIVVMAYTPFGSLFPSK-AQPDAP 784 GL+ P Q+E + + +L FC+ DIV++AY+ GS + P++P Sbjct: 181 GLKYKPVCNQVECHPYFNRSKLLDFCKSKDIVLVAYSALGSQRDKRWVDPNSP 233 >AF524864-1|AAO13380.1| 316|Homo sapiens aldo-ketoreductase protein. Length = 316 Score = 151 bits (367), Expect = 3e-36 Identities = 89/231 (38%), Positives = 130/231 (56%), Gaps = 13/231 (5%) Frame = +2 Query: 131 LQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQV 310 ++LS+ +P+V LGTW P GKV ++AV A++AGY HID AY Y E +V Sbjct: 5 VELSTKAKMPIVGLGTWKS--PLGKV-------KEAVKVAIDAGYRHIDCAYVYQNEHEV 55 Query: 311 GRALTKKFSE-GLKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPIA 487 G A+ +K E +KRE +FI +KLW ++ ER V A K+L++ L Y+D+YLIHWP Sbjct: 56 GEAIQEKIQEKAVKREDLFIASKLWPTFFERPLVRKAFEKTLKDPKLSYLDVYLIHWPQG 115 Query: 488 MFENDTLLDNVD----------FLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDS-G 634 D L D FLD W M + GL K++G+SNF+ QI+++++ G Sbjct: 116 FKSGDDLFPKDDKGNAIGGKATFLDAWEAMEELVDEGLVKALGVSNFSHFQIEKLLNKPG 175 Query: 635 LE-XPSALQIELNLNLQQPELFKFCRENDIVVMAYTPFGSLFPSKAQPDAP 784 L+ P Q+E + L Q +L ++C I V AY+P GS A+P+ P Sbjct: 176 LKYKPVTNQVECHPYLTQEKLIQYCHSKGITVTAYSPLGSPDRPWAKPEDP 226 >AF149416-1|AAF07272.2| 323|Homo sapiens 3-alpha hydroxysteroid dehydrogenase type IIb protein. Length = 323 Score = 151 bits (366), Expect = 3e-36 Identities = 89/233 (38%), Positives = 135/233 (57%), Gaps = 15/233 (6%) Frame = +2 Query: 131 LQLSSGGNIPVVALGTWLGHR-PKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQ 307 ++L+ G +PV+ GT+ P+ K ++V+ A+EAG+ HID+A+ Y E+Q Sbjct: 8 VKLNDGHFMPVLGFGTYAPPEVPRSKALEVSK-------LAIEAGFRHIDSAHLYNNEEQ 60 Query: 308 VGRALTKKFSEG-LKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPI 484 VG A+ K ++G +KRE IF T+KLW++ H E V PAL SL+ L+YVDLYLIH P+ Sbjct: 61 VGLAIRSKIADGSVKREDIFYTSKLWSTSHRPELVRPALENSLKKAQLDYVDLYLIHSPM 120 Query: 485 AMFENDTL----------LDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDS- 631 ++ + L D VD TW M K GL KSIG+SNFN+ Q++ I++ Sbjct: 121 SLKPGEELSPTDENGKVIFDIVDLCTTWEAMEKCKDAGLAKSIGVSNFNRRQLEMILNKP 180 Query: 632 GLE-XPSALQIELNLNLQQPELFKFCRENDIVVMAYTPFGSLFPSK-AQPDAP 784 GL+ P Q+E + + +L FC+ DIV++AY+ GS + P++P Sbjct: 181 GLKYKPVCNQVECHPYFNRSKLLDFCKSKDIVLVAYSALGSQRDKRWVDPNSP 233 >BC005387-1|AAH05387.1| 316|Homo sapiens aldo-keto reductase family 1, member B1 (aldose reductase) protein. Length = 316 Score = 149 bits (361), Expect = 1e-35 Identities = 92/231 (39%), Positives = 135/231 (58%), Gaps = 13/231 (5%) Frame = +2 Query: 131 LQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQV 310 L L++G +P++ LGTW P G+V + AV A++ GY HID A+ Y E++V Sbjct: 5 LLLNNGAKMPILGLGTWKS--PPGQVTE-------AVKVAIDVGYRHIDCAHVYQNENEV 55 Query: 311 GRALTKKFSEGL-KRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPIA 487 G A+ +K E + KRE +FI +KLW +YHE+ V A +K+L +L L+Y+DLYLIHWP Sbjct: 56 GVAIQEKLREQVVKREELFIVSKLWCTYHEKGLVKGACQKTLSDLKLDYLDLYLIHWPTG 115 Query: 488 ------MFEND----TLLDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDS-G 634 F D + + + LDT M + GL K+IGISNFN Q++ I++ G Sbjct: 116 FKPGKEFFPLDESGNVVPSDTNILDTRAAMEELVDEGLVKAIGISNFNHLQVEMILNKPG 175 Query: 635 LE-XPSALQIELNLNLQQPELFKFCRENDIVVMAYTPFGSLFPSKAQPDAP 784 L+ P+ QIE + L Q +L ++C+ IVV AY+P GS A+P+ P Sbjct: 176 LKYKPAVNQIECHPYLTQEKLIQYCQSKGIVVTAYSPLGSPDRPWAKPEDP 226 >AF263242-1|AAK58523.1| 320|Homo sapiens aldo-keto reductase loopADR protein. Length = 320 Score = 94.7 bits (225), Expect(2) = 4e-35 Identities = 52/113 (46%), Positives = 68/113 (60%), Gaps = 1/113 (0%) Frame = +2 Query: 149 GNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQVGRALTK 328 G+IP V L +W GKV + AV A++AGY H D AY Y E +VG + Sbjct: 2 GDIPAVGLSSWKAS--PGKVTE-------AVKEAIDAGYRHFDCAYFYHNEREVGAGIRC 52 Query: 329 KFSEG-LKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPI 484 K EG ++RE +FI TKLW + H++ V A RKSL+ L L Y+DLYLIHWP+ Sbjct: 53 KIKEGAVRREDLFIATKLWCTCHKKSLVETACRKSLKALKLNYLDLYLIHWPM 105 Score = 74.5 bits (175), Expect(2) = 4e-35 Identities = 38/86 (44%), Positives = 50/86 (58%), Gaps = 2/86 (2%) Frame = +2 Query: 497 NDTLLDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDS-GLE-XPSALQIELN 670 N + + DFLDTW M D GL K+IG+SNFN EQ++R+++ GL P QIE + Sbjct: 139 NMVIPSDTDFLDTWEAMEDLVITGLVKNIGVSNFNHEQLERLLNKPGLRFKPLTNQIECH 198 Query: 671 LNLQQPELFKFCRENDIVVMAYTPFG 748 L Q L FC+ D+ V AY P G Sbjct: 199 PYLTQKNLISFCQSRDVSVTAYRPLG 224 >BC002862-1|AAH02862.1| 307|Homo sapiens AKR1CL2 protein protein. Length = 307 Score = 94.7 bits (225), Expect(2) = 4e-35 Identities = 52/113 (46%), Positives = 68/113 (60%), Gaps = 1/113 (0%) Frame = +2 Query: 149 GNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQVGRALTK 328 G+IP V L +W GKV + AV A++AGY H D AY Y E +VG + Sbjct: 2 GDIPAVGLSSWKAS--PGKVTE-------AVKEAIDAGYRHFDCAYFYHNEREVGAGIRC 52 Query: 329 KFSEG-LKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPI 484 K EG ++RE +FI TKLW + H++ V A RKSL+ L L Y+DLYLIHWP+ Sbjct: 53 KIKEGAVRREDLFIATKLWCTCHKKSLVETACRKSLKALKLNYLDLYLIHWPM 105 Score = 74.5 bits (175), Expect(2) = 4e-35 Identities = 38/86 (44%), Positives = 50/86 (58%), Gaps = 2/86 (2%) Frame = +2 Query: 497 NDTLLDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDS-GLE-XPSALQIELN 670 N + + DFLDTW M D GL K+IG+SNFN EQ++R+++ GL P QIE + Sbjct: 139 NMVIPSDTDFLDTWEAMEDLVITGLVKNIGVSNFNHEQLERLLNKPGLRFKPLTNQIECH 198 Query: 671 LNLQQPELFKFCRENDIVVMAYTPFG 748 L Q L FC+ D+ V AY P G Sbjct: 199 PYLTQKNLISFCQSRDVSVTAYRPLG 224 >AB055603-1|BAC54568.1| 307|Homo sapiens aldo-keto reductase related protein 4 protein. Length = 307 Score = 94.7 bits (225), Expect(2) = 4e-35 Identities = 52/113 (46%), Positives = 68/113 (60%), Gaps = 1/113 (0%) Frame = +2 Query: 149 GNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQVGRALTK 328 G+IP V L +W GKV + AV A++AGY H D AY Y E +VG + Sbjct: 2 GDIPAVGLSSWKAS--PGKVTE-------AVKEAIDAGYRHFDCAYFYHNEREVGAGIRC 52 Query: 329 KFSEG-LKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPI 484 K EG ++RE +FI TKLW + H++ V A RKSL+ L L Y+DLYLIHWP+ Sbjct: 53 KIKEGAVRREDLFIATKLWCTCHKKSLVETACRKSLKALKLNYLDLYLIHWPM 105 Score = 74.5 bits (175), Expect(2) = 4e-35 Identities = 38/86 (44%), Positives = 50/86 (58%), Gaps = 2/86 (2%) Frame = +2 Query: 497 NDTLLDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDS-GLE-XPSALQIELN 670 N + + DFLDTW M D GL K+IG+SNFN EQ++R+++ GL P QIE + Sbjct: 139 NMVIPSDTDFLDTWEAMEDLVITGLVKNIGVSNFNHEQLERLLNKPGLRFKPLTNQIECH 198 Query: 671 LNLQQPELFKFCRENDIVVMAYTPFG 748 L Q L FC+ D+ V AY P G Sbjct: 199 PYLTQKNLISFCQSRDVSVTAYRPLG 224 >Z28339-1|CAA82193.1| 326|Homo sapiens delta 4-3-oxosteroid 5 beta-reductase protein. Length = 326 Score = 146 bits (354), Expect = 9e-35 Identities = 86/220 (39%), Positives = 128/220 (58%), Gaps = 13/220 (5%) Frame = +2 Query: 131 LQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQV 310 + LS G +IP++ LGT+ + K T+ V A++ GY HID AY Y E +V Sbjct: 10 IPLSDGNSIPIIGLGTYSEPKSTPKGACATS-----VKVAIDTGYRHIDGAYIYQNEHEV 64 Query: 311 GRALTKKFSEG-LKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPIA 487 G A+ +K +EG ++RE IF KLW + H E V P L ++L L L+YVDLY+I P+A Sbjct: 65 GEAIREKIAEGKVRREDIFYCGKLWATNHVPEMVRPTLERTLRVLQLDYVDLYIIEVPMA 124 Query: 488 MFENDTLL---DNVDFL-------DTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDS-G 634 D + +N +L TW M K GL KS+G+SNFN+ Q++ I++ G Sbjct: 125 FKPGDEIYPRDENGKWLYHKSNLCATWEAMEACKDAGLVKSLGVSNFNRRQLELILNKPG 184 Query: 635 LE-XPSALQIELNLNLQQPELFKFCRENDIVVMAYTPFGS 751 L+ P + Q+E + QP+L KFC+++DIV+ AY+P G+ Sbjct: 185 LKHKPVSNQVECHPYFTQPKLLKFCQQHDIVITAYSPLGT 224 >BC130627-1|AAI30628.1| 326|Homo sapiens aldo-keto reductase family 1, member D1 (delta 4-3-ketosteroid-5-beta-reductase protein. Length = 326 Score = 146 bits (354), Expect = 9e-35 Identities = 86/220 (39%), Positives = 128/220 (58%), Gaps = 13/220 (5%) Frame = +2 Query: 131 LQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQV 310 + LS G +IP++ LGT+ + K T+ V A++ GY HID AY Y E +V Sbjct: 10 IPLSDGNSIPIIGLGTYSEPKSTPKGACATS-----VKVAIDTGYRHIDGAYIYQNEHEV 64 Query: 311 GRALTKKFSEG-LKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPIA 487 G A+ +K +EG ++RE IF KLW + H E V P L ++L L L+YVDLY+I P+A Sbjct: 65 GEAIREKIAEGKVRREDIFYCGKLWATNHVPEMVRPTLERTLRVLQLDYVDLYIIEVPMA 124 Query: 488 MFENDTLL---DNVDFL-------DTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDS-G 634 D + +N +L TW M K GL KS+G+SNFN+ Q++ I++ G Sbjct: 125 FKPGDEIYPRDENGKWLYHKSNLCATWEAMEACKDAGLVKSLGVSNFNRRQLELILNKPG 184 Query: 635 LE-XPSALQIELNLNLQQPELFKFCRENDIVVMAYTPFGS 751 L+ P + Q+E + QP+L KFC+++DIV+ AY+P G+ Sbjct: 185 LKHKPVSNQVECHPYFTQPKLLKFCQQHDIVITAYSPLGT 224 >BC130625-1|AAI30626.1| 326|Homo sapiens aldo-keto reductase family 1, member D1 (delta 4-3-ketosteroid-5-beta-reductase protein. Length = 326 Score = 146 bits (354), Expect = 9e-35 Identities = 86/220 (39%), Positives = 128/220 (58%), Gaps = 13/220 (5%) Frame = +2 Query: 131 LQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQV 310 + LS G +IP++ LGT+ + K T+ V A++ GY HID AY Y E +V Sbjct: 10 IPLSDGNSIPIIGLGTYSEPKSTPKGACATS-----VKVAIDTGYRHIDGAYIYQNEHEV 64 Query: 311 GRALTKKFSEG-LKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPIA 487 G A+ +K +EG ++RE IF KLW + H E V P L ++L L L+YVDLY+I P+A Sbjct: 65 GEAIREKIAEGKVRREDIFYCGKLWATNHVPEMVRPTLERTLRVLQLDYVDLYIIEVPMA 124 Query: 488 MFENDTLL---DNVDFL-------DTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDS-G 634 D + +N +L TW M K GL KS+G+SNFN+ Q++ I++ G Sbjct: 125 FKPGDEIYPRDENGKWLYHKSNLCATWEAMEACKDAGLVKSLGVSNFNRRQLELILNKPG 184 Query: 635 LE-XPSALQIELNLNLQQPELFKFCRENDIVVMAYTPFGS 751 L+ P + Q+E + QP+L KFC+++DIV+ AY+P G+ Sbjct: 185 LKHKPVSNQVECHPYFTQPKLLKFCQQHDIVITAYSPLGT 224 >AF283659-1|AAG39381.1| 326|Homo sapiens 5-beta steroid reductase protein. Length = 326 Score = 146 bits (354), Expect = 9e-35 Identities = 86/220 (39%), Positives = 128/220 (58%), Gaps = 13/220 (5%) Frame = +2 Query: 131 LQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQV 310 + LS G +IP++ LGT+ + K T+ V A++ GY HID AY Y E +V Sbjct: 10 IPLSDGNSIPIIGLGTYSEPKSTPKGACATS-----VKVAIDTGYRHIDGAYIYQNEHEV 64 Query: 311 GRALTKKFSEG-LKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPIA 487 G A+ +K +EG ++RE IF KLW + H E V P L ++L L L+YVDLY+I P+A Sbjct: 65 GEAIREKIAEGKVRREDIFYCGKLWATNHVPEMVRPTLERTLRVLQLDYVDLYIIEVPMA 124 Query: 488 MFENDTLL---DNVDFL-------DTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDS-G 634 D + +N +L TW M K GL KS+G+SNFN+ Q++ I++ G Sbjct: 125 FKPGDEIYPRDENGKWLYHKSNLCATWEAMEACKDAGLVKSLGVSNFNRRQLELILNKPG 184 Query: 635 LE-XPSALQIELNLNLQQPELFKFCRENDIVVMAYTPFGS 751 L+ P + Q+E + QP+L KFC+++DIV+ AY+P G+ Sbjct: 185 LKHKPVSNQVECHPYFTQPKLLKFCQQHDIVITAYSPLGT 224 >AL713867-3|CAI16410.1| 247|Homo sapiens aldo-keto reductase family 1, member C1 (dihydrodiol dehydrogenase 1; 20-alpha protein. Length = 247 Score = 127 bits (306), Expect = 6e-29 Identities = 71/162 (43%), Positives = 101/162 (62%), Gaps = 13/162 (8%) Frame = +2 Query: 305 QVGRALTKKFSEG-LKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWP 481 +VG A+ K ++G +KRE IF T+KLW + H E V PAL +SL+NL L+YVDLYLIH+P Sbjct: 26 EVGLAIRSKIADGSVKREDIFYTSKLWCNSHRPELVRPALERSLKNLQLDYVDLYLIHFP 85 Query: 482 IAM---------FENDTLL-DNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDS 631 +++ EN +L D VD TW + K GL KSIG+SNFN+ Q++ I++ Sbjct: 86 VSVKPGEEVIPKDENGKILFDTVDLCATWEAVEKCKDAGLAKSIGVSNFNRRQLEMILNK 145 Query: 632 -GLE-XPSALQIELNLNLQQPELFKFCRENDIVVMAYTPFGS 751 GL+ P Q+E + Q +L FC+ DIV++AY+ GS Sbjct: 146 PGLKYKPVCNQVECHPYFNQRKLLDFCKSKDIVLVAYSALGS 187 >AB040821-1|BAC54566.1| 263|Homo sapiens aldo-keto reductase related protein 2 protein. Length = 263 Score = 94.7 bits (225), Expect(2) = 8e-29 Identities = 52/113 (46%), Positives = 68/113 (60%), Gaps = 1/113 (0%) Frame = +2 Query: 149 GNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQVGRALTK 328 G+IP V L +W GKV + AV A++AGY H D AY Y E +VG + Sbjct: 2 GDIPAVGLSSWKAS--PGKVTE-------AVKEAIDAGYRHFDCAYFYHNEREVGAGIRC 52 Query: 329 KFSEG-LKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPI 484 K EG ++RE +FI TKLW + H++ V A RKSL+ L L Y+DLYLIHWP+ Sbjct: 53 KIKEGAVRREDLFIATKLWCTCHKKSLVETACRKSLKALKLNYLDLYLIHWPM 105 Score = 53.2 bits (122), Expect(2) = 8e-29 Identities = 27/65 (41%), Positives = 39/65 (60%), Gaps = 2/65 (3%) Frame = +2 Query: 497 NDTLLDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDS-GLE-XPSALQIELN 670 N + + DFLDTW M D GL K+IG+SNFN EQ++R+++ GL P QI + Sbjct: 139 NMVIPSDTDFLDTWEAMEDLVITGLVKNIGVSNFNHEQLERLLNKPGLRFKPLTNQILIR 198 Query: 671 LNLQQ 685 +Q+ Sbjct: 199 FQIQR 203 >AB040820-1|BAC54565.1| 250|Homo sapiens aldo-keto reductase related protein 1 protein. Length = 250 Score = 94.7 bits (225), Expect(2) = 8e-29 Identities = 52/113 (46%), Positives = 68/113 (60%), Gaps = 1/113 (0%) Frame = +2 Query: 149 GNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQVGRALTK 328 G+IP V L +W GKV + AV A++AGY H D AY Y E +VG + Sbjct: 2 GDIPAVGLSSWKAS--PGKVTE-------AVKEAIDAGYRHFDCAYFYHNEREVGAGIRC 52 Query: 329 KFSEG-LKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPI 484 K EG ++RE +FI TKLW + H++ V A RKSL+ L L Y+DLYLIHWP+ Sbjct: 53 KIKEGAVRREDLFIATKLWCTCHKKSLVETACRKSLKALKLNYLDLYLIHWPM 105 Score = 53.2 bits (122), Expect(2) = 8e-29 Identities = 27/65 (41%), Positives = 39/65 (60%), Gaps = 2/65 (3%) Frame = +2 Query: 497 NDTLLDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDS-GLE-XPSALQIELN 670 N + + DFLDTW M D GL K+IG+SNFN EQ++R+++ GL P QI + Sbjct: 139 NMVIPSDTDFLDTWEAMEDLVITGLVKNIGVSNFNHEQLERLLNKPGLRFKPLTNQILIR 198 Query: 671 LNLQQ 685 +Q+ Sbjct: 199 FQIQR 203 >AL391427-2|CAI14727.1| 302|Homo sapiens aldo-keto reductase family 1, member C-like 1 protein. Length = 302 Score = 111 bits (266), Expect = 4e-24 Identities = 81/259 (31%), Positives = 130/259 (50%), Gaps = 14/259 (5%) Frame = +2 Query: 128 TLQLSSGGNIPVVALGTWL-GHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIED 304 +++L+ G +PV+ GT+ H PK + + T A++ G+ HID+AY Y E+ Sbjct: 10 SVRLNDGPFMPVLGFGTYAPDHTPKSQAAEATK-------VAIDVGFRHIDSAYLYQNEE 62 Query: 305 QVGRALTKKFSEG-LKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWP 481 +VG+A+ +K ++G +KRE IF T KLW ++ E V PAL +SL+ L +YVDL++IH P Sbjct: 63 EVGQAIWEKIADGTVKREEIFYTIKLWATFFRAELVHPALERSLKKLGPDYVDLFIIHVP 122 Query: 482 IAMFE-----------NDTLLDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIID 628 AM + + +L+ V+ DTW + K GL NQ Sbjct: 123 FAMKQPGKELLPKDASGEIILETVELCDTWELELILNKPGLRYK---PTCNQ-------- 171 Query: 629 SGLEXPSALQIELNLNLQQPELFKFCRENDIVVMAYTPFGS-LFPSKAQPDAPRRGLTMN 805 +E + L Q +L +FC+ DIV++AY+ GS P PD P Sbjct: 172 ---------VVECHPYLNQSKLLEFCKSKDIVLVAYSALGSQRDPQWVDPDCPHLLEEPI 222 Query: 806 VSSVSPXNTTNCPPVALXF 862 + S++ ++ + VAL + Sbjct: 223 LKSIAKKHSRSPGQVALRY 241 >AL355303-1|CAI14201.1| 302|Homo sapiens aldo-keto reductase family 1, member C-like 1 protein. Length = 302 Score = 111 bits (266), Expect = 4e-24 Identities = 81/259 (31%), Positives = 130/259 (50%), Gaps = 14/259 (5%) Frame = +2 Query: 128 TLQLSSGGNIPVVALGTWL-GHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIED 304 +++L+ G +PV+ GT+ H PK + + T A++ G+ HID+AY Y E+ Sbjct: 10 SVRLNDGPFMPVLGFGTYAPDHTPKSQAAEATK-------VAIDVGFRHIDSAYLYQNEE 62 Query: 305 QVGRALTKKFSEG-LKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWP 481 +VG+A+ +K ++G +KRE IF T KLW ++ E V PAL +SL+ L +YVDL++IH P Sbjct: 63 EVGQAIWEKIADGTVKREEIFYTIKLWATFFRAELVHPALERSLKKLGPDYVDLFIIHVP 122 Query: 482 IAMFE-----------NDTLLDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIID 628 AM + + +L+ V+ DTW + K GL NQ Sbjct: 123 FAMKQPGKELLPKDASGEIILETVELCDTWELELILNKPGLRYK---PTCNQ-------- 171 Query: 629 SGLEXPSALQIELNLNLQQPELFKFCRENDIVVMAYTPFGS-LFPSKAQPDAPRRGLTMN 805 +E + L Q +L +FC+ DIV++AY+ GS P PD P Sbjct: 172 ---------VVECHPYLNQSKLLEFCKSKDIVLVAYSALGSQRDPQWVDPDCPHLLEEPI 222 Query: 806 VSSVSPXNTTNCPPVALXF 862 + S++ ++ + VAL + Sbjct: 223 LKSIAKKHSRSPGQVALRY 241 >AL355480-2|CAI22458.1| 147|Homo sapiens aldo-keto reductase family 1, member A1 (aldehydela) protein. Length = 147 Score = 108 bits (260), Expect = 2e-23 Identities = 58/124 (46%), Positives = 76/124 (61%), Gaps = 2/124 (1%) Frame = +2 Query: 137 LSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQVGR 316 L +G +P++ LGTW K + QV + AV YAL GY HID A YG E ++G Sbjct: 8 LHTGQKMPLIGLGTW-----KSEPGQV----KAAVKYALSVGYRHIDCAAIYGNEPEIGE 58 Query: 317 ALTKKFSEG--LKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPIAM 490 AL + G + RE +F+T+KLWN+ H E V PALRK+L +L LEY+DLYL+HWP A Sbjct: 59 ALKEDVGPGKAVPREELFVTSKLWNTKHHPEDVEPALRKTLADLQLEYLDLYLMHWPYAF 118 Query: 491 FEND 502 D Sbjct: 119 ERGD 122 >BC101205-1|AAI01206.1| 129|Homo sapiens aldo-keto reductase family 1, member C-like 1 protein. Length = 129 Score = 97.5 bits (232), Expect = 6e-20 Identities = 50/123 (40%), Positives = 78/123 (63%), Gaps = 2/123 (1%) Frame = +2 Query: 128 TLQLSSGGNIPVVALGTWL-GHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIED 304 +++L+ G +PV+ GT+ H PK + + T A++ G+ HID+AY Y E+ Sbjct: 10 SVRLNDGPFMPVLGFGTYAPDHTPKSQAAEATK-------VAIDVGFRHIDSAYLYQNEE 62 Query: 305 QVGRALTKKFSEG-LKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWP 481 +VG+A+ +K ++G +KRE IF T KLW ++ E V PAL +SL+ L +YVDL++IH P Sbjct: 63 EVGQAIWEKIADGTVKREEIFYTIKLWATFFRAELVHPALERSLKKLGPDYVDLFIIHVP 122 Query: 482 IAM 490 AM Sbjct: 123 FAM 125 >BC101204-1|AAI01205.1| 129|Homo sapiens aldo-keto reductase family 1, member C-like 1 protein. Length = 129 Score = 97.5 bits (232), Expect = 6e-20 Identities = 50/123 (40%), Positives = 78/123 (63%), Gaps = 2/123 (1%) Frame = +2 Query: 128 TLQLSSGGNIPVVALGTWL-GHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIED 304 +++L+ G +PV+ GT+ H PK + + T A++ G+ HID+AY Y E+ Sbjct: 10 SVRLNDGPFMPVLGFGTYAPDHTPKSQAAEATK-------VAIDVGFRHIDSAYLYQNEE 62 Query: 305 QVGRALTKKFSEG-LKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWP 481 +VG+A+ +K ++G +KRE IF T KLW ++ E V PAL +SL+ L +YVDL++IH P Sbjct: 63 EVGQAIWEKIADGTVKREEIFYTIKLWATFFRAELVHPALERSLKKLGPDYVDLFIIHVP 122 Query: 482 IAM 490 AM Sbjct: 123 FAM 125 >AK131335-1|BAD18494.1| 129|Homo sapiens protein ( Homo sapiens cDNA FLJ16347 fis, clone TESTI2036288, moderately similar to PROSTAGLANDIN-F SYNTHASE 1 (EC 1.1.1.188). ). Length = 129 Score = 97.5 bits (232), Expect = 6e-20 Identities = 50/123 (40%), Positives = 78/123 (63%), Gaps = 2/123 (1%) Frame = +2 Query: 128 TLQLSSGGNIPVVALGTWL-GHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIED 304 +++L+ G +PV+ GT+ H PK + + T A++ G+ HID+AY Y E+ Sbjct: 10 SVRLNDGPFMPVLGFGTYAPDHTPKSQAAEATK-------VAIDVGFRHIDSAYLYQNEE 62 Query: 305 QVGRALTKKFSEG-LKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWP 481 +VG+A+ +K ++G +KRE IF T KLW ++ E V PAL +SL+ L +YVDL++IH P Sbjct: 63 EVGQAIWEKIADGTVKREEIFYTIKLWATFFRAELVHPALERSLKKLGPDYVDLFIIHVP 122 Query: 482 IAM 490 AM Sbjct: 123 FAM 125 >AB040822-1|BAC54567.1| 222|Homo sapiens aldo-keto reductase related protein 3 protein. Length = 222 Score = 94.7 bits (225), Expect(2) = 2e-19 Identities = 52/113 (46%), Positives = 68/113 (60%), Gaps = 1/113 (0%) Frame = +2 Query: 149 GNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQVGRALTK 328 G+IP V L +W GKV + AV A++AGY H D AY Y E +VG + Sbjct: 2 GDIPAVGLSSWKAS--PGKVTE-------AVKEAIDAGYRHFDCAYFYHNEREVGAGIRC 52 Query: 329 KFSEG-LKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPI 484 K EG ++RE +FI TKLW + H++ V A RKSL+ L L Y+DLYLIHWP+ Sbjct: 53 KIKEGAVRREDLFIATKLWCTCHKKSLVETACRKSLKALKLNYLDLYLIHWPM 105 Score = 21.4 bits (43), Expect(2) = 2e-19 Identities = 8/18 (44%), Positives = 11/18 (61%) Frame = +2 Query: 497 NDTLLDNVDFLDTWRGMI 550 N + + DFLDTW +I Sbjct: 139 NMVIPSDTDFLDTWEILI 156 >AB037902-1|BAA92887.1| 130|Homo sapiens truncated aldo-keto reductase protein. Length = 130 Score = 90.2 bits (214), Expect = 9e-18 Identities = 46/122 (37%), Positives = 77/122 (63%), Gaps = 1/122 (0%) Frame = +2 Query: 128 TLQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQ 307 +++L+ G +P++ GT + + V ++N E+AV A++ GY HID+AY + E+ Sbjct: 8 SVKLNDGKFMPILGFGTSVARK-----VAMSN-VEEAVQVAIDVGYRHIDSAYTHLNEEG 61 Query: 308 VGRALTKKFSEG-LKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPI 484 +G+A+ KK + G +KR+ IF TTK+W ++ E V L SL+ L L Y+DLYL H+P+ Sbjct: 62 IGQAIRKKIANGTVKRKDIFYTTKVWGTFSRPELVQRGLEMSLKKLQLSYMDLYLFHFPV 121 Query: 485 AM 490 + Sbjct: 122 PL 123 >AK058142-1|BAB71682.1| 146|Homo sapiens protein ( Homo sapiens cDNA FLJ25413 fis, clone TST03402, highly similar to 3-OXO-5-BETA-STEROID 4-DEHYDROGENASE (EC 1.3.99.6). ). Length = 146 Score = 71.3 bits (167), Expect = 4e-12 Identities = 33/75 (44%), Positives = 51/75 (68%), Gaps = 2/75 (2%) Frame = +2 Query: 533 TWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDS-GLEX-PSALQIELNLNLQQPELFKFC 706 TW M K GL KS+G+SNFN+ Q++ I++ GL+ P + Q+E + QP+L KFC Sbjct: 28 TWEAMEACKDAGLVKSLGVSNFNRRQLELILNKPGLKHKPVSNQVECHPYFTQPKLLKFC 87 Query: 707 RENDIVVMAYTPFGS 751 +++DIV+ AY+P G+ Sbjct: 88 QQHDIVITAYSPLGT 102 >U33429-1|AAC50955.1| 367|Homo sapiens K+ channel beta 2 subunit protein. Length = 367 Score = 49.2 bits (112), Expect = 2e-05 Identities = 42/124 (33%), Positives = 60/124 (48%), Gaps = 11/124 (8%) Frame = +2 Query: 143 SGGNIPVVALGTWLGHRPKGKVVQVTND-TEQAVIYALEAGYTHIDTAYKYGI---EDQV 310 SG + + LGTW+ Q+T++ EQ + A + G DTA Y E + Sbjct: 45 SGLRVSCLGLGTWVTFGG-----QITDEMAEQLMTLAYDNGINLFDTAEVYAAGKAEVVL 99 Query: 311 GRALTKKFSEGLKRESIFITTKL-WNSYHE------REQVIPALRKSLENLNLEYVDLYL 469 G + KK G +R S+ ITTK+ W E R+ +I L+ SLE L LEYVD+ Sbjct: 100 GNIIKKK---GWRRSSLVITTKIFWGGKAETERGLSRKHIIEGLKASLERLQLEYVDVVF 156 Query: 470 IHWP 481 + P Sbjct: 157 ANRP 160 >CR542287-1|CAG47082.1| 353|Homo sapiens KCNAB2 protein. Length = 353 Score = 49.2 bits (112), Expect = 2e-05 Identities = 42/124 (33%), Positives = 60/124 (48%), Gaps = 11/124 (8%) Frame = +2 Query: 143 SGGNIPVVALGTWLGHRPKGKVVQVTND-TEQAVIYALEAGYTHIDTAYKYGI---EDQV 310 SG + + LGTW+ Q+T++ EQ + A + G DTA Y E + Sbjct: 31 SGLRVSCLGLGTWVTFGG-----QITDEMAEQLMTLAYDNGINLFDTAEVYAAGKAEVVL 85 Query: 311 GRALTKKFSEGLKRESIFITTKL-WNSYHE------REQVIPALRKSLENLNLEYVDLYL 469 G + KK G +R S+ ITTK+ W E R+ +I L+ SLE L LEYVD+ Sbjct: 86 GNIIKKK---GWRRSSLVITTKIFWGGKAETERGLSRKHIIEGLKASLERLQLEYVDVVF 142 Query: 470 IHWP 481 + P Sbjct: 143 ANRP 146 >BC130413-1|AAI30414.1| 367|Homo sapiens potassium voltage-gated channel, shaker-related subfamily, beta member 2 protein. Length = 367 Score = 49.2 bits (112), Expect = 2e-05 Identities = 42/124 (33%), Positives = 60/124 (48%), Gaps = 11/124 (8%) Frame = +2 Query: 143 SGGNIPVVALGTWLGHRPKGKVVQVTND-TEQAVIYALEAGYTHIDTAYKYGI---EDQV 310 SG + + LGTW+ Q+T++ EQ + A + G DTA Y E + Sbjct: 45 SGLRVSCLGLGTWVTFGG-----QITDEMAEQLMTLAYDNGINLFDTAEVYAAGKAEVVL 99 Query: 311 GRALTKKFSEGLKRESIFITTKL-WNSYHE------REQVIPALRKSLENLNLEYVDLYL 469 G + KK G +R S+ ITTK+ W E R+ +I L+ SLE L LEYVD+ Sbjct: 100 GNIIKKK---GWRRSSLVITTKIFWGGKAETERGLSRKHIIEGLKASLERLQLEYVDVVF 156 Query: 470 IHWP 481 + P Sbjct: 157 ANRP 160 >BC126424-1|AAI26425.1| 367|Homo sapiens potassium voltage-gated channel, shaker-related subfamily, beta member 2 protein. Length = 367 Score = 49.2 bits (112), Expect = 2e-05 Identities = 42/124 (33%), Positives = 60/124 (48%), Gaps = 11/124 (8%) Frame = +2 Query: 143 SGGNIPVVALGTWLGHRPKGKVVQVTND-TEQAVIYALEAGYTHIDTAYKYGI---EDQV 310 SG + + LGTW+ Q+T++ EQ + A + G DTA Y E + Sbjct: 45 SGLRVSCLGLGTWVTFGG-----QITDEMAEQLMTLAYDNGINLFDTAEVYAAGKAEVVL 99 Query: 311 GRALTKKFSEGLKRESIFITTKL-WNSYHE------REQVIPALRKSLENLNLEYVDLYL 469 G + KK G +R S+ ITTK+ W E R+ +I L+ SLE L LEYVD+ Sbjct: 100 GNIIKKK---GWRRSSLVITTKIFWGGKAETERGLSRKHIIEGLKASLERLQLEYVDVVF 156 Query: 470 IHWP 481 + P Sbjct: 157 ANRP 160 >BC110351-1|AAI10352.1| 395|Homo sapiens KCNAB2 protein protein. Length = 395 Score = 49.2 bits (112), Expect = 2e-05 Identities = 42/124 (33%), Positives = 60/124 (48%), Gaps = 11/124 (8%) Frame = +2 Query: 143 SGGNIPVVALGTWLGHRPKGKVVQVTND-TEQAVIYALEAGYTHIDTAYKYGI---EDQV 310 SG + + LGTW+ Q+T++ EQ + A + G DTA Y E + Sbjct: 45 SGLRVSCLGLGTWVTFGG-----QITDEMAEQLMTLAYDNGINLFDTAEVYAAGKAEVVL 99 Query: 311 GRALTKKFSEGLKRESIFITTKL-WNSYHE------REQVIPALRKSLENLNLEYVDLYL 469 G + KK G +R S+ ITTK+ W E R+ +I L+ SLE L LEYVD+ Sbjct: 100 GNIIKKK---GWRRSSLVITTKIFWGGKAETERGLSRKHIIEGLKASLERLQLEYVDVVF 156 Query: 470 IHWP 481 + P Sbjct: 157 ANRP 160 >AL035406-6|CAI19886.1| 253|Homo sapiens potassium voltage-gated channel, shaker-related subfamily, beta member 2 protein. Length = 253 Score = 49.2 bits (112), Expect = 2e-05 Identities = 42/124 (33%), Positives = 60/124 (48%), Gaps = 11/124 (8%) Frame = +2 Query: 143 SGGNIPVVALGTWLGHRPKGKVVQVTND-TEQAVIYALEAGYTHIDTAYKYGI---EDQV 310 SG + + LGTW+ Q+T++ EQ + A + G DTA Y E + Sbjct: 45 SGLRVSCLGLGTWVTFGG-----QITDEMAEQLMTLAYDNGINLFDTAEVYAAGKAEVVL 99 Query: 311 GRALTKKFSEGLKRESIFITTKL-WNSYHE------REQVIPALRKSLENLNLEYVDLYL 469 G + KK G +R S+ ITTK+ W E R+ +I L+ SLE L LEYVD+ Sbjct: 100 GNIIKKK---GWRRSSLVITTKIFWGGKAETERGLSRKHIIEGLKASLERLQLEYVDVVF 156 Query: 470 IHWP 481 + P Sbjct: 157 ANRP 160 >AL035406-5|CAI19887.1| 254|Homo sapiens potassium voltage-gated channel, shaker-related subfamily, beta member 2 protein. Length = 254 Score = 49.2 bits (112), Expect = 2e-05 Identities = 42/124 (33%), Positives = 60/124 (48%), Gaps = 11/124 (8%) Frame = +2 Query: 143 SGGNIPVVALGTWLGHRPKGKVVQVTND-TEQAVIYALEAGYTHIDTAYKYGI---EDQV 310 SG + + LGTW+ Q+T++ EQ + A + G DTA Y E + Sbjct: 31 SGLRVSCLGLGTWVTFGG-----QITDEMAEQLMTLAYDNGINLFDTAEVYAAGKAEVVL 85 Query: 311 GRALTKKFSEGLKRESIFITTKL-WNSYHE------REQVIPALRKSLENLNLEYVDLYL 469 G + KK G +R S+ ITTK+ W E R+ +I L+ SLE L LEYVD+ Sbjct: 86 GNIIKKK---GWRRSSLVITTKIFWGGKAETERGLSRKHIIEGLKASLERLQLEYVDVVF 142 Query: 470 IHWP 481 + P Sbjct: 143 ANRP 146 >AL035406-4|CAC08512.1| 367|Homo sapiens potassium voltage-gated channel, shaker-related subfamily, beta member 2 protein. Length = 367 Score = 49.2 bits (112), Expect = 2e-05 Identities = 42/124 (33%), Positives = 60/124 (48%), Gaps = 11/124 (8%) Frame = +2 Query: 143 SGGNIPVVALGTWLGHRPKGKVVQVTND-TEQAVIYALEAGYTHIDTAYKYGI---EDQV 310 SG + + LGTW+ Q+T++ EQ + A + G DTA Y E + Sbjct: 45 SGLRVSCLGLGTWVTFGG-----QITDEMAEQLMTLAYDNGINLFDTAEVYAAGKAEVVL 99 Query: 311 GRALTKKFSEGLKRESIFITTKL-WNSYHE------REQVIPALRKSLENLNLEYVDLYL 469 G + KK G +R S+ ITTK+ W E R+ +I L+ SLE L LEYVD+ Sbjct: 100 GNIIKKK---GWRRSSLVITTKIFWGGKAETERGLSRKHIIEGLKASLERLQLEYVDVVF 156 Query: 470 IHWP 481 + P Sbjct: 157 ANRP 160 >AL035406-3|CAI19885.1| 353|Homo sapiens potassium voltage-gated channel, shaker-related subfamily, beta member 2 protein. Length = 353 Score = 49.2 bits (112), Expect = 2e-05 Identities = 42/124 (33%), Positives = 60/124 (48%), Gaps = 11/124 (8%) Frame = +2 Query: 143 SGGNIPVVALGTWLGHRPKGKVVQVTND-TEQAVIYALEAGYTHIDTAYKYGI---EDQV 310 SG + + LGTW+ Q+T++ EQ + A + G DTA Y E + Sbjct: 31 SGLRVSCLGLGTWVTFGG-----QITDEMAEQLMTLAYDNGINLFDTAEVYAAGKAEVVL 85 Query: 311 GRALTKKFSEGLKRESIFITTKL-WNSYHE------REQVIPALRKSLENLNLEYVDLYL 469 G + KK G +R S+ ITTK+ W E R+ +I L+ SLE L LEYVD+ Sbjct: 86 GNIIKKK---GWRRSSLVITTKIFWGGKAETERGLSRKHIIEGLKASLERLQLEYVDVVF 142 Query: 470 IHWP 481 + P Sbjct: 143 ANRP 146 >AK131252-1|BAD18431.1| 415|Homo sapiens protein ( Homo sapiens cDNA FLJ16180 fis, clone BRHIP3000240, highly similar to Homo sapiens potassium channel beta 2 subunit (HKvbeta2.2) mRNA. ). Length = 415 Score = 49.2 bits (112), Expect = 2e-05 Identities = 42/124 (33%), Positives = 60/124 (48%), Gaps = 11/124 (8%) Frame = +2 Query: 143 SGGNIPVVALGTWLGHRPKGKVVQVTND-TEQAVIYALEAGYTHIDTAYKYGI---EDQV 310 SG + + LGTW+ Q+T++ EQ + A + G DTA Y E + Sbjct: 78 SGLRVSCLGLGTWVTFGG-----QITDEMAEQLMTLAYDNGINLFDTAEVYAAGKAEVVL 132 Query: 311 GRALTKKFSEGLKRESIFITTKL-WNSYHE------REQVIPALRKSLENLNLEYVDLYL 469 G + KK G +R S+ ITTK+ W E R+ +I L+ SLE L LEYVD+ Sbjct: 133 GNIIKKK---GWRRSSLVITTKIFWGGKAETERGLSRKHIIEGLKASLERLQLEYVDVVF 189 Query: 470 IHWP 481 + P Sbjct: 190 ANRP 193 >AF044253-1|AAB99859.1| 353|Homo sapiens potassium channel beta 2 subunit protein. Length = 353 Score = 49.2 bits (112), Expect = 2e-05 Identities = 42/124 (33%), Positives = 60/124 (48%), Gaps = 11/124 (8%) Frame = +2 Query: 143 SGGNIPVVALGTWLGHRPKGKVVQVTND-TEQAVIYALEAGYTHIDTAYKYGI---EDQV 310 SG + + LGTW+ Q+T++ EQ + A + G DTA Y E + Sbjct: 31 SGLRVSCLGLGTWVTFGG-----QITDEMAEQLMTLAYDNGINLFDTAEVYAAGKAEVVL 85 Query: 311 GRALTKKFSEGLKRESIFITTKL-WNSYHE------REQVIPALRKSLENLNLEYVDLYL 469 G + KK G +R S+ ITTK+ W E R+ +I L+ SLE L LEYVD+ Sbjct: 86 GNIIKKK---GWRRSSLVITTKIFWGGKAETERGLSRKHIIEGLKASLERLQLEYVDVVF 142 Query: 470 IHWP 481 + P Sbjct: 143 ANRP 146 >AF029749-1|AAB84170.1| 367|Homo sapiens potassium channel beta 2 subunit protein. Length = 367 Score = 49.2 bits (112), Expect = 2e-05 Identities = 42/124 (33%), Positives = 60/124 (48%), Gaps = 11/124 (8%) Frame = +2 Query: 143 SGGNIPVVALGTWLGHRPKGKVVQVTND-TEQAVIYALEAGYTHIDTAYKYGI---EDQV 310 SG + + LGTW+ Q+T++ EQ + A + G DTA Y E + Sbjct: 45 SGLRVSCLGLGTWVTFGG-----QITDEMAEQLMTLAYDNGINLFDTAEVYAAGKAEVVL 99 Query: 311 GRALTKKFSEGLKRESIFITTKL-WNSYHE------REQVIPALRKSLENLNLEYVDLYL 469 G + KK G +R S+ ITTK+ W E R+ +I L+ SLE L LEYVD+ Sbjct: 100 GNIIKKK---GWRRSSLVITTKIFWGGKAETERGLSRKHIIEGLKASLERLQLEYVDVVF 156 Query: 470 IHWP 481 + P Sbjct: 157 ANRP 160 >CR542264-1|CAG47060.1| 353|Homo sapiens KCNAB2 protein. Length = 353 Score = 46.8 bits (106), Expect = 1e-04 Identities = 41/124 (33%), Positives = 59/124 (47%), Gaps = 11/124 (8%) Frame = +2 Query: 143 SGGNIPVVALGTWLGHRPKGKVVQVTND-TEQAVIYALEAGYTHIDTAYKYGI---EDQV 310 SG + + LGTW+ Q+T++ EQ + A + G DTA Y E + Sbjct: 31 SGLRVSCLGLGTWVTFGG-----QITDEMAEQLMTLAYDNGINLFDTAEVYAAGKAEVVL 85 Query: 311 GRALTKKFSEGLKRESIFITTKL-WNSYHE------REQVIPALRKSLENLNLEYVDLYL 469 G + KK G +R S+ ITTK+ W E R+ +I L+ SLE LEYVD+ Sbjct: 86 GNIIKKK---GWRRSSLVITTKIFWGGKAETERGLSRKHIIEGLKASLERRQLEYVDVVF 142 Query: 470 IHWP 481 + P Sbjct: 143 ANRP 146 >BC099634-1|AAH99634.1| 404|Homo sapiens potassium voltage-gated channel, shaker-related subfamily, beta member 3 protein. Length = 404 Score = 45.6 bits (103), Expect = 2e-04 Identities = 41/118 (34%), Positives = 56/118 (47%), Gaps = 11/118 (9%) Frame = +2 Query: 143 SGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVI-YALEAGYTHIDTAYKYGI---EDQV 310 SG + + LGTW+ Q++++T + V+ A E G DTA Y E + Sbjct: 86 SGLRVSCLGLGTWVTFGS-----QISDETAEDVLTVAYEHGVNLFDTAEVYAAGKAERTL 140 Query: 311 GRALTKKFSEGLKRESIFITTKL-WNSYHE------REQVIPALRKSLENLNLEYVDL 463 G L K G +R S ITTK+ W E R+ +I LR SLE L L YVD+ Sbjct: 141 GNILKSK---GWRRSSYVITTKIFWGGQAETERGLSRKHIIEGLRGSLERLQLGYVDI 195 >BC096234-1|AAH96234.1| 404|Homo sapiens potassium voltage-gated channel, shaker-related subfamily, beta member 3 protein. Length = 404 Score = 45.6 bits (103), Expect = 2e-04 Identities = 41/118 (34%), Positives = 56/118 (47%), Gaps = 11/118 (9%) Frame = +2 Query: 143 SGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVI-YALEAGYTHIDTAYKYGI---EDQV 310 SG + + LGTW+ Q++++T + V+ A E G DTA Y E + Sbjct: 86 SGLRVSCLGLGTWVTFGS-----QISDETAEDVLTVAYEHGVNLFDTAEVYAAGKAERTL 140 Query: 311 GRALTKKFSEGLKRESIFITTKL-WNSYHE------REQVIPALRKSLENLNLEYVDL 463 G L K G +R S ITTK+ W E R+ +I LR SLE L L YVD+ Sbjct: 141 GNILKSK---GWRRSSYVITTKIFWGGQAETERGLSRKHIIEGLRGSLERLQLGYVDI 195 >BC096232-1|AAH96232.1| 404|Homo sapiens potassium voltage-gated channel, shaker-related subfamily, beta member 3 protein. Length = 404 Score = 45.6 bits (103), Expect = 2e-04 Identities = 41/118 (34%), Positives = 56/118 (47%), Gaps = 11/118 (9%) Frame = +2 Query: 143 SGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVI-YALEAGYTHIDTAYKYGI---EDQV 310 SG + + LGTW+ Q++++T + V+ A E G DTA Y E + Sbjct: 86 SGLRVSCLGLGTWVTFGS-----QISDETAEDVLTVAYEHGVNLFDTAEVYAAGKAERTL 140 Query: 311 GRALTKKFSEGLKRESIFITTKL-WNSYHE------REQVIPALRKSLENLNLEYVDL 463 G L K G +R S ITTK+ W E R+ +I LR SLE L L YVD+ Sbjct: 141 GNILKSK---GWRRSSYVITTKIFWGGQAETERGLSRKHIIEGLRGSLERLQLGYVDI 195 >AB028065-1|BAA88489.1| 67|Homo sapiens prostaglandin F synthase protein. Length = 67 Score = 45.6 bits (103), Expect = 2e-04 Identities = 19/41 (46%), Positives = 26/41 (63%) Frame = +2 Query: 506 LLDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIID 628 + D VD TW M K GL KSIG+SNFN+ Q++ I++ Sbjct: 15 IFDIVDLCTTWEAMEKCKDAGLAKSIGVSNFNRRQLEMILN 55 >AF016411-1|AAB92499.1| 404|Homo sapiens KCNA3.1B protein. Length = 404 Score = 44.4 bits (100), Expect = 6e-04 Identities = 40/117 (34%), Positives = 55/117 (47%), Gaps = 11/117 (9%) Frame = +2 Query: 146 GGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVI-YALEAGYTHIDTAYKYGI---EDQVG 313 G + + LGTW+ Q++++T + V+ A E G DTA Y E +G Sbjct: 87 GVRVSCLGLGTWVTFGS-----QISDETAEDVLTVAYEHGVNLFDTAEVYAAGKAERTLG 141 Query: 314 RALTKKFSEGLKRESIFITTKL-WNSYHE------REQVIPALRKSLENLNLEYVDL 463 L K G +R S ITTK+ W E R+ +I LR SLE L L YVD+ Sbjct: 142 NILKSK---GWRRSSYVITTKIFWGGQAETERGLSRKHIIEGLRGSLERLQLGYVDI 195 >AB037905-2|BAA92890.1| 45|Homo sapiens truncated aldo-keto reductase protein. Length = 45 Score = 37.9 bits (84), Expect = 0.049 Identities = 15/38 (39%), Positives = 23/38 (60%) Frame = +2 Query: 377 LWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPIAM 490 +W ++ E V L SL+ L L Y+DLYL H+P+ + Sbjct: 1 VWGTFSRPELVQRGLEMSLKKLQLSYMDLYLFHFPVPL 38 >AF026947-1|AAC52104.1| 330|Homo sapiens aflatoxin aldehyde reductase AFAR protein. Length = 330 Score = 35.9 bits (79), Expect = 0.20 Identities = 48/187 (25%), Positives = 74/187 (39%), Gaps = 10/187 (5%) Frame = +2 Query: 236 AVIYALEAGYTHIDTAYKY--GIEDQVGRALTKKFSEGLKRESIFITTKLWNSYH-EREQ 406 AV LE G+T +DTA+ Y G + + L G R I W+ + + Sbjct: 30 AVRAFLERGHTELDTAFMYSDGQSETILGGLGLGLGGGDCRVKIATKANPWDGKSLKPDS 89 Query: 407 VIPALRKSLENLNLEYVDLYLIHWPIAMFENDTLLDNVDFLDTWRGMIDAKKLGLTKSIG 586 V L SL+ L VDL+ +H P ++ T ++ +T + G +G Sbjct: 90 VRSQLETSLKRLQCPQVDLFYLHTP----DHGTPVE-----ETLHACQRLHQEGKFVELG 140 Query: 587 ISNFNQEQIQRII----DSGLEXPSALQIELNLNLQQ--PELFKFCRENDIVVMAYTPF- 745 +SN+ ++ I +G P+ Q N +Q ELF R + AY P Sbjct: 141 LSNYASWEVAEICTLCKSNGWILPTVYQGMYNATTRQVETELFPCLRHFGLRFYAYNPLA 200 Query: 746 GSLFPSK 766 G L K Sbjct: 201 GGLLTGK 207 >Y16675-1|CAA76347.1| 330|Homo sapiens aflatoxin B1-aldehyde reductase protein. Length = 330 Score = 35.5 bits (78), Expect = 0.26 Identities = 48/187 (25%), Positives = 74/187 (39%), Gaps = 10/187 (5%) Frame = +2 Query: 236 AVIYALEAGYTHIDTAYKY--GIEDQVGRALTKKFSEGLKRESIFITTKLWNSYH-EREQ 406 AV LE G+T +DTA+ Y G + + L G R I W+ + + Sbjct: 30 AVRAFLERGHTELDTAFMYSDGQSETILGGLGLGLGGGDCRVKIATKANPWDGKSLKPDS 89 Query: 407 VIPALRKSLENLNLEYVDLYLIHWPIAMFENDTLLDNVDFLDTWRGMIDAKKLGLTKSIG 586 V L SL+ L VDL+ +H P ++ T ++ +T + G +G Sbjct: 90 VRSQLETSLKRLQCPQVDLFYLHAP----DHGTPVE-----ETLHACQRLHQEGKFVELG 140 Query: 587 ISNFNQEQIQRII----DSGLEXPSALQIELNLNLQQ--PELFKFCRENDIVVMAYTPF- 745 +SN+ ++ I +G P+ Q N +Q ELF R + AY P Sbjct: 141 LSNYASWEVAEICTLCKSNGWILPTVYQGMYNATTRQVETELFPCLRHFGLRFYAYNPLA 200 Query: 746 GSLFPSK 766 G L K Sbjct: 201 GGLLTGK 207 >BT007347-1|AAP36011.1| 330|Homo sapiens aldo-keto reductase family 7, member A2 (aflatoxin aldehyde reductase) protein. Length = 330 Score = 35.5 bits (78), Expect = 0.26 Identities = 48/187 (25%), Positives = 74/187 (39%), Gaps = 10/187 (5%) Frame = +2 Query: 236 AVIYALEAGYTHIDTAYKY--GIEDQVGRALTKKFSEGLKRESIFITTKLWNSYH-EREQ 406 AV LE G+T +DTA+ Y G + + L G R I W+ + + Sbjct: 30 AVRAFLERGHTELDTAFMYSDGQSETILGGLGLGLGGGDCRVKIATKANPWDGKSLKPDS 89 Query: 407 VIPALRKSLENLNLEYVDLYLIHWPIAMFENDTLLDNVDFLDTWRGMIDAKKLGLTKSIG 586 V L SL+ L VDL+ +H P ++ T ++ +T + G +G Sbjct: 90 VRSQLETSLKRLQCPQVDLFYLHAP----DHGTPVE-----ETLHACQRLHQEGKFVELG 140 Query: 587 ISNFNQEQIQRII----DSGLEXPSALQIELNLNLQQ--PELFKFCRENDIVVMAYTPF- 745 +SN+ ++ I +G P+ Q N +Q ELF R + AY P Sbjct: 141 LSNYASWEVAEICTLCKSNGWILPTVYQGMYNATTRQVETELFPCLRHFGLRFYAYNPLA 200 Query: 746 GSLFPSK 766 G L K Sbjct: 201 GGLLTGK 207 >BC013996-1|AAH13996.1| 330|Homo sapiens AKR7A2 protein protein. Length = 330 Score = 35.5 bits (78), Expect = 0.26 Identities = 48/187 (25%), Positives = 74/187 (39%), Gaps = 10/187 (5%) Frame = +2 Query: 236 AVIYALEAGYTHIDTAYKY--GIEDQVGRALTKKFSEGLKRESIFITTKLWNSYH-EREQ 406 AV LE G+T +DTA+ Y G + + L G R I W+ + + Sbjct: 30 AVRAFLERGHTELDTAFMYSDGQSETILGGLGLGLGGGDCRVKIATKANPWDGKSLKPDS 89 Query: 407 VIPALRKSLENLNLEYVDLYLIHWPIAMFENDTLLDNVDFLDTWRGMIDAKKLGLTKSIG 586 V L SL+ L VDL+ +H P ++ T ++ +T + G +G Sbjct: 90 VRSQLETSLKRLQCPQVDLFYLHAP----DHGTPVE-----ETLHACQRLHQEGKFVELG 140 Query: 587 ISNFNQEQIQRII----DSGLEXPSALQIELNLNLQQ--PELFKFCRENDIVVMAYTPF- 745 +SN+ ++ I +G P+ Q N +Q ELF R + AY P Sbjct: 141 LSNYASWEVAEICTLCKSNGWILPTVYQGMYNATTRQVETELFPCLRHFGLRFYAYNPLA 200 Query: 746 GSLFPSK 766 G L K Sbjct: 201 GGLLTGK 207 >BC012171-1|AAH12171.1| 330|Homo sapiens AKR7A2 protein protein. Length = 330 Score = 35.5 bits (78), Expect = 0.26 Identities = 48/187 (25%), Positives = 74/187 (39%), Gaps = 10/187 (5%) Frame = +2 Query: 236 AVIYALEAGYTHIDTAYKY--GIEDQVGRALTKKFSEGLKRESIFITTKLWNSYH-EREQ 406 AV LE G+T +DTA+ Y G + + L G R I W+ + + Sbjct: 30 AVRAFLERGHTELDTAFMYSDGQSETILGGLGLGLGGGDCRVKIATKANPWDGKSLKPDS 89 Query: 407 VIPALRKSLENLNLEYVDLYLIHWPIAMFENDTLLDNVDFLDTWRGMIDAKKLGLTKSIG 586 V L SL+ L VDL+ +H P ++ T ++ +T + G +G Sbjct: 90 VRSQLETSLKRLQCPQVDLFYLHAP----DHGTPVE-----ETLHACQRLHQEGKFVELG 140 Query: 587 ISNFNQEQIQRII----DSGLEXPSALQIELNLNLQQ--PELFKFCRENDIVVMAYTPF- 745 +SN+ ++ I +G P+ Q N +Q ELF R + AY P Sbjct: 141 LSNYASWEVAEICTLCKSNGWILPTVYQGMYNATTRQVETELFPCLRHFGLRFYAYNPLA 200 Query: 746 GSLFPSK 766 G L K Sbjct: 201 GGLLTGK 207 >BC011586-1|AAH11586.1| 330|Homo sapiens AKR7A2 protein protein. Length = 330 Score = 35.5 bits (78), Expect = 0.26 Identities = 48/187 (25%), Positives = 74/187 (39%), Gaps = 10/187 (5%) Frame = +2 Query: 236 AVIYALEAGYTHIDTAYKY--GIEDQVGRALTKKFSEGLKRESIFITTKLWNSYH-EREQ 406 AV LE G+T +DTA+ Y G + + L G R I W+ + + Sbjct: 30 AVRAFLERGHTELDTAFMYSDGQSETILGGLGLGLGGGDCRVKIATKANPWDGKSLKPDS 89 Query: 407 VIPALRKSLENLNLEYVDLYLIHWPIAMFENDTLLDNVDFLDTWRGMIDAKKLGLTKSIG 586 V L SL+ L VDL+ +H P ++ T ++ +T + G +G Sbjct: 90 VRSQLETSLKRLQCPQVDLFYLHAP----DHGTPVE-----ETLHACQRLHQEGKFVELG 140 Query: 587 ISNFNQEQIQRII----DSGLEXPSALQIELNLNLQQ--PELFKFCRENDIVVMAYTPF- 745 +SN+ ++ I +G P+ Q N +Q ELF R + AY P Sbjct: 141 LSNYASWEVAEICTLCKSNGWILPTVYQGMYNATTRQVETELFPCLRHFGLRFYAYNPLA 200 Query: 746 GSLFPSK 766 G L K Sbjct: 201 GGLLTGK 207 >BC010852-1|AAH10852.1| 330|Homo sapiens AKR7A2 protein protein. Length = 330 Score = 35.5 bits (78), Expect = 0.26 Identities = 48/187 (25%), Positives = 74/187 (39%), Gaps = 10/187 (5%) Frame = +2 Query: 236 AVIYALEAGYTHIDTAYKY--GIEDQVGRALTKKFSEGLKRESIFITTKLWNSYH-EREQ 406 AV LE G+T +DTA+ Y G + + L G R I W+ + + Sbjct: 30 AVRAFLERGHTELDTAFMYSDGQSETILGGLGLGLGGGDCRVKIATKANPWDGKSLKPDS 89 Query: 407 VIPALRKSLENLNLEYVDLYLIHWPIAMFENDTLLDNVDFLDTWRGMIDAKKLGLTKSIG 586 V L SL+ L VDL+ +H P ++ T ++ +T + G +G Sbjct: 90 VRSQLETSLKRLQCPQVDLFYLHAP----DHGTPVE-----ETLHACQRLHQEGKFVELG 140 Query: 587 ISNFNQEQIQRII----DSGLEXPSALQIELNLNLQQ--PELFKFCRENDIVVMAYTPF- 745 +SN+ ++ I +G P+ Q N +Q ELF R + AY P Sbjct: 141 LSNYASWEVAEICTLCKSNGWILPTVYQGMYNATTRQVETELFPCLRHFGLRFYAYNPLA 200 Query: 746 GSLFPSK 766 G L K Sbjct: 201 GGLLTGK 207 >BC007352-1|AAH07352.2| 358|Homo sapiens AKR7A2 protein protein. Length = 358 Score = 35.5 bits (78), Expect = 0.26 Identities = 48/187 (25%), Positives = 74/187 (39%), Gaps = 10/187 (5%) Frame = +2 Query: 236 AVIYALEAGYTHIDTAYKY--GIEDQVGRALTKKFSEGLKRESIFITTKLWNSYH-EREQ 406 AV LE G+T +DTA+ Y G + + L G R I W+ + + Sbjct: 58 AVRAFLERGHTELDTAFMYSDGQSETILGGLGLGLGGGDCRVKIATKANPWDGKSLKPDS 117 Query: 407 VIPALRKSLENLNLEYVDLYLIHWPIAMFENDTLLDNVDFLDTWRGMIDAKKLGLTKSIG 586 V L SL+ L VDL+ +H P ++ T ++ +T + G +G Sbjct: 118 VRSQLETSLKRLQCPQVDLFYLHAP----DHGTPVE-----ETLHACQRLHQEGKFVELG 168 Query: 587 ISNFNQEQIQRII----DSGLEXPSALQIELNLNLQQ--PELFKFCRENDIVVMAYTPF- 745 +SN+ ++ I +G P+ Q N +Q ELF R + AY P Sbjct: 169 LSNYASWEVAEICTLCKSNGWILPTVYQGMYNATTRQVETELFPCLRHFGLRFYAYNPLA 228 Query: 746 GSLFPSK 766 G L K Sbjct: 229 GGLLTGK 235 >BC004111-1|AAH04111.3| 330|Homo sapiens AKR7A2 protein protein. Length = 330 Score = 35.5 bits (78), Expect = 0.26 Identities = 48/187 (25%), Positives = 74/187 (39%), Gaps = 10/187 (5%) Frame = +2 Query: 236 AVIYALEAGYTHIDTAYKY--GIEDQVGRALTKKFSEGLKRESIFITTKLWNSYH-EREQ 406 AV LE G+T +DTA+ Y G + + L G R I W+ + + Sbjct: 30 AVRAFLERGHTELDTAFMYSDGQSETILGGLGLGLGGGDCRVKIATKANPWDGKSLKPDS 89 Query: 407 VIPALRKSLENLNLEYVDLYLIHWPIAMFENDTLLDNVDFLDTWRGMIDAKKLGLTKSIG 586 V L SL+ L VDL+ +H P ++ T ++ +T + G +G Sbjct: 90 VRSQLETSLKRLQCPQVDLFYLHAP----DHGTPVE-----ETLHACQRLHQEGKFVELG 140 Query: 587 ISNFNQEQIQRII----DSGLEXPSALQIELNLNLQQ--PELFKFCRENDIVVMAYTPF- 745 +SN+ ++ I +G P+ Q N +Q ELF R + AY P Sbjct: 141 LSNYASWEVAEICTLCKSNGWILPTVYQGMYNATTRQVETELFPCLRHFGLRFYAYNPLA 200 Query: 746 GSLFPSK 766 G L K Sbjct: 201 GGLLTGK 207 >AL035413-8|CAB72321.1| 330|Homo sapiens aldo-keto reductase family 7, member A2 (aflatoxin aldehyde reductase) protein. Length = 330 Score = 35.5 bits (78), Expect = 0.26 Identities = 48/187 (25%), Positives = 74/187 (39%), Gaps = 10/187 (5%) Frame = +2 Query: 236 AVIYALEAGYTHIDTAYKY--GIEDQVGRALTKKFSEGLKRESIFITTKLWNSYH-EREQ 406 AV LE G+T +DTA+ Y G + + L G R I W+ + + Sbjct: 30 AVRAFLERGHTELDTAFMYSDGQSETILGGLGLGLGGGDCRVKIATKANPWDGKSLKPDS 89 Query: 407 VIPALRKSLENLNLEYVDLYLIHWPIAMFENDTLLDNVDFLDTWRGMIDAKKLGLTKSIG 586 V L SL+ L VDL+ +H P ++ T ++ +T + G +G Sbjct: 90 VRSQLETSLKRLQCPQVDLFYLHAP----DHGTPVE-----ETLHACQRLHQEGKFVELG 140 Query: 587 ISNFNQEQIQRII----DSGLEXPSALQIELNLNLQQ--PELFKFCRENDIVVMAYTPF- 745 +SN+ ++ I +G P+ Q N +Q ELF R + AY P Sbjct: 141 LSNYASWEVAEICTLCKSNGWILPTVYQGMYNATTRQVETELFPCLRHFGLRFYAYNPLA 200 Query: 746 GSLFPSK 766 G L K Sbjct: 201 GGLLTGK 207 >M64590-1|AAA36463.1| 1020|Homo sapiens glycine decarboxylase protein. Length = 1020 Score = 31.1 bits (67), Expect = 5.6 Identities = 14/37 (37%), Positives = 24/37 (64%) Frame = +2 Query: 347 KRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYV 457 KR S F+T +++NSYH ++ ++K LEN ++ V Sbjct: 514 KRTSPFLTHQVFNSYHSETNIVRYMKK-LENKDISLV 549 >M63635-1|AAA36478.1| 1020|Homo sapiens glycine decarboxylase protein. Length = 1020 Score = 31.1 bits (67), Expect = 5.6 Identities = 14/37 (37%), Positives = 24/37 (64%) Frame = +2 Query: 347 KRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYV 457 KR S F+T +++NSYH ++ ++K LEN ++ V Sbjct: 514 KRTSPFLTHQVFNSYHSETNIVRYMKK-LENKDISLV 549 >D90239-1|BAA14286.1| 1020|Homo sapiens glycine decarboxylase precursor protein. Length = 1020 Score = 31.1 bits (67), Expect = 5.6 Identities = 14/37 (37%), Positives = 24/37 (64%) Frame = +2 Query: 347 KRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYV 457 KR S F+T +++NSYH ++ ++K LEN ++ V Sbjct: 514 KRTSPFLTHQVFNSYHSETNIVRYMKK-LENKDISLV 549 >BC111995-1|AAI11996.1| 1020|Homo sapiens glycine dehydrogenase (decarboxylating) protein. Length = 1020 Score = 31.1 bits (67), Expect = 5.6 Identities = 14/37 (37%), Positives = 24/37 (64%) Frame = +2 Query: 347 KRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYV 457 KR S F+T +++NSYH ++ ++K LEN ++ V Sbjct: 514 KRTSPFLTHQVFNSYHSETNIVRYMKK-LENKDISLV 549 >BC111993-1|AAI11994.1| 1020|Homo sapiens glycine dehydrogenase (decarboxylating) protein. Length = 1020 Score = 31.1 bits (67), Expect = 5.6 Identities = 14/37 (37%), Positives = 24/37 (64%) Frame = +2 Query: 347 KRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYV 457 KR S F+T +++NSYH ++ ++K LEN ++ V Sbjct: 514 KRTSPFLTHQVFNSYHSETNIVRYMKK-LENKDISLV 549 >BC042420-1|AAH42420.2| 331|Homo sapiens aldo-keto reductase family 7, member A3 (aflatoxin aldehyde reductase) protein. Length = 331 Score = 31.1 bits (67), Expect = 5.6 Identities = 49/191 (25%), Positives = 78/191 (40%), Gaps = 11/191 (5%) Frame = +2 Query: 227 TEQAVIYA-LEAGYTHIDTAYKY--GIEDQVGRALTKKFSEGLKRESIFI-TTKLWNSYH 394 T AV A LE G+T IDTA+ Y G + + L + R I L+ + Sbjct: 27 TSAAVTRAFLERGHTEIDTAFVYSEGQSETILGGLGLRLGGSDCRVKIDTKAIPLFGNSL 86 Query: 395 EREQVIPALRKSLENLNLEYVDLYLIHWPIAMFENDTLLDNVDFLDTWRGMIDAKKLGLT 574 + + + L SL+ L VDL+ +H P ++ T ++ +T R + G Sbjct: 87 KPDSLRFQLETSLKRLQCPRVDLFYLHMP----DHSTPVE-----ETLRACHQLHQEGKF 137 Query: 575 KSIGISNFNQEQIQRII----DSGLEXPSALQIELNLNLQQ--PELFKFCRENDIVVMAY 736 +G+SN+ ++ I +G P+ Q N +Q ELF R + A+ Sbjct: 138 MELGLSNYAAWEVAEICTLCKSNGWILPTVYQGMYNAITRQVETELFPCLRHFGLRFYAF 197 Query: 737 TPF-GSLFPSK 766 P G L K Sbjct: 198 NPLAGGLLTGK 208 >BC031562-1|AAH31562.1| 331|Homo sapiens aldo-keto reductase family 7, member A3 (aflatoxin aldehyde reductase) protein. Length = 331 Score = 31.1 bits (67), Expect = 5.6 Identities = 49/191 (25%), Positives = 78/191 (40%), Gaps = 11/191 (5%) Frame = +2 Query: 227 TEQAVIYA-LEAGYTHIDTAYKY--GIEDQVGRALTKKFSEGLKRESIFI-TTKLWNSYH 394 T AV A LE G+T IDTA+ Y G + + L + R I L+ + Sbjct: 27 TSAAVTRAFLERGHTEIDTAFVYSEGQSETILGGLGLRLGGSDCRVKIDTKAIPLFGNSL 86 Query: 395 EREQVIPALRKSLENLNLEYVDLYLIHWPIAMFENDTLLDNVDFLDTWRGMIDAKKLGLT 574 + + + L SL+ L VDL+ +H P ++ T ++ +T R + G Sbjct: 87 KPDSLRFQLETSLKRLQCPRVDLFYLHMP----DHSTPVE-----ETLRACHQLHQEGKF 137 Query: 575 KSIGISNFNQEQIQRII----DSGLEXPSALQIELNLNLQQ--PELFKFCRENDIVVMAY 736 +G+SN+ ++ I +G P+ Q N +Q ELF R + A+ Sbjct: 138 MELGLSNYAAWEVAEICTLCKSNGWILPTVYQGMYNAITRQVETELFPCLRHFGLRFYAF 197 Query: 737 TPF-GSLFPSK 766 P G L K Sbjct: 198 NPLAGGLLTGK 208 >AL353718-2|CAH74116.1| 1036|Homo sapiens glycine dehydrogenase (decarboxylating) protein. Length = 1036 Score = 31.1 bits (67), Expect = 5.6 Identities = 14/37 (37%), Positives = 24/37 (64%) Frame = +2 Query: 347 KRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYV 457 KR S F+T +++NSYH ++ ++K LEN ++ V Sbjct: 514 KRTSPFLTHQVFNSYHSETNIVRYMKK-LENKDISLV 549 >AL162411-3|CAH69992.1| 1036|Homo sapiens glycine dehydrogenase (decarboxylating) protein. Length = 1036 Score = 31.1 bits (67), Expect = 5.6 Identities = 14/37 (37%), Positives = 24/37 (64%) Frame = +2 Query: 347 KRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYV 457 KR S F+T +++NSYH ++ ++K LEN ++ V Sbjct: 514 KRTSPFLTHQVFNSYHSETNIVRYMKK-LENKDISLV 549 >AJ271799-1|CAC81076.1| 331|Homo sapiens aflatoxin B1 aldehyde reductase 2 protein. Length = 331 Score = 31.1 bits (67), Expect = 5.6 Identities = 49/191 (25%), Positives = 78/191 (40%), Gaps = 11/191 (5%) Frame = +2 Query: 227 TEQAVIYA-LEAGYTHIDTAYKY--GIEDQVGRALTKKFSEGLKRESIFI-TTKLWNSYH 394 T AV A LE G+T IDTA+ Y G + + L + R I L+ + Sbjct: 27 TSAAVTRAFLERGHTEIDTAFVYSEGQSETILGGLGLRLGGSDCRVKIDTKAIPLFGNSL 86 Query: 395 EREQVIPALRKSLENLNLEYVDLYLIHWPIAMFENDTLLDNVDFLDTWRGMIDAKKLGLT 574 + + + L SL+ L VDL+ +H P ++ T ++ +T R + G Sbjct: 87 KPDSLRFQLETSLKRLQCPRVDLFYLHMP----DHSTPVE-----ETLRACHQLHQEGKF 137 Query: 575 KSIGISNFNQEQIQRII----DSGLEXPSALQIELNLNLQQ--PELFKFCRENDIVVMAY 736 +G+SN+ ++ I +G P+ Q N +Q ELF R + A+ Sbjct: 138 MELGLSNYAAWEVAEICTLCKSNGWILPTVYQGMYNAITRQVETELFPCLRHFGLRFYAF 197 Query: 737 TPF-GSLFPSK 766 P G L K Sbjct: 198 NPLAGGLLTGK 208 >AF246134-1|AAK28443.2| 331|Homo sapiens glycine decarboxylase P-protein protein. Length = 331 Score = 31.1 bits (67), Expect = 5.6 Identities = 14/37 (37%), Positives = 24/37 (64%) Frame = +2 Query: 347 KRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYV 457 KR S F+T +++NSYH ++ ++K LEN ++ V Sbjct: 276 KRTSPFLTHQVFNSYHSETNIVRYMKK-LENKDISLV 311 >AF040639-1|AAD02195.1| 331|Homo sapiens aflatoxin B1-aldehyde reductase protein. Length = 331 Score = 31.1 bits (67), Expect = 5.6 Identities = 49/191 (25%), Positives = 78/191 (40%), Gaps = 11/191 (5%) Frame = +2 Query: 227 TEQAVIYA-LEAGYTHIDTAYKY--GIEDQVGRALTKKFSEGLKRESIFI-TTKLWNSYH 394 T AV A LE G+T IDTA+ Y G + + L + R I L+ + Sbjct: 27 TSAAVTRAFLERGHTEIDTAFVYSDGQSETILGGLGLRLGGSDCRVKIDTKAIPLFGNSL 86 Query: 395 EREQVIPALRKSLENLNLEYVDLYLIHWPIAMFENDTLLDNVDFLDTWRGMIDAKKLGLT 574 + + + L SL+ L VDL+ +H P ++ T ++ +T R + G Sbjct: 87 KPDSLRFQLETSLKRLQCPRVDLFYLHMP----DHSTPVE-----ETLRACHQLHQEGKF 137 Query: 575 KSIGISNFNQEQIQRII----DSGLEXPSALQIELNLNLQQ--PELFKFCRENDIVVMAY 736 +G+SN+ ++ I +G P+ Q N +Q ELF R + A+ Sbjct: 138 MELGLSNYAAWEVAEICTLCKSNGWILPTVYQGMYNAITRQVETELFPCLRHFGLRFYAF 197 Query: 737 TPF-GSLFPSK 766 P G L K Sbjct: 198 NPLAGGLLTGK 208 >BC029488-1|AAH29488.1| 294|Homo sapiens sperm acrosome associated 1 protein. Length = 294 Score = 30.7 bits (66), Expect = 7.4 Identities = 17/56 (30%), Positives = 25/56 (44%) Frame = +2 Query: 83 CLSALCFTSADLIVPTLQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYA 250 C + L T L++ LQ + G N+ L H +G+ ND+E A YA Sbjct: 8 CSAGLLMTVGWLLLAGLQSARGTNVTAAVQDAGLAHEGEGEEETENNDSETAENYA 63 >BC025709-1|AAH25709.1| 331|Homo sapiens aldo-keto reductase family 7, member A3 (aflatoxin aldehyde reductase) protein. Length = 331 Score = 30.7 bits (66), Expect = 7.4 Identities = 49/191 (25%), Positives = 78/191 (40%), Gaps = 11/191 (5%) Frame = +2 Query: 227 TEQAVIYA-LEAGYTHIDTAYKY--GIEDQVGRALTKKFSEGLKRESIFI-TTKLWNSYH 394 T AV A LE G+T IDTA+ Y G + + L + R I L+ + Sbjct: 27 TSAAVTRAFLERGHTEIDTAFVYSEGQSETILGGLGLRLGGSDCRVKIDTKAIPLFGNSL 86 Query: 395 EREQVIPALRKSLENLNLEYVDLYLIHWPIAMFENDTLLDNVDFLDTWRGMIDAKKLGLT 574 + + + L SL+ L VDL+ +H P ++ T ++ +T R + G Sbjct: 87 KPDSLRFQLETSLKRLQCPRVDLFYLHMP----DHSTPVE-----ETLRACHQLHQEGKF 137 Query: 575 KSIGISNFNQEQIQRII----DSGLEXPSALQIELNLNLQQ--PELFKFCRENDIVVMAY 736 +G+SN+ ++ I +G P+ Q N +Q ELF R + A+ Sbjct: 138 VELGLSNYAAWEVAEICTLCKSNGWILPTVYQGMYNAITRQVETELFPCLRHFGLRFYAF 197 Query: 737 TPF-GSLFPSK 766 P G L K Sbjct: 198 NPLAGGLLTGK 208 >AL136096-1|CAI19915.1| 294|Homo sapiens sperm acrosome associated 1 protein. Length = 294 Score = 30.7 bits (66), Expect = 7.4 Identities = 17/56 (30%), Positives = 25/56 (44%) Frame = +2 Query: 83 CLSALCFTSADLIVPTLQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYA 250 C + L T L++ LQ + G N+ L H +G+ ND+E A YA Sbjct: 8 CSAGLLMTVGWLLLAGLQSARGTNVTAAVQDAGLAHEGEGEEETENNDSETAENYA 63 >AL035413-11|CAI22232.1| 331|Homo sapiens aldo-keto reductase family 7, member A3 (aflatoxin aldehyde reductase) protein. Length = 331 Score = 30.7 bits (66), Expect = 7.4 Identities = 49/191 (25%), Positives = 78/191 (40%), Gaps = 11/191 (5%) Frame = +2 Query: 227 TEQAVIYA-LEAGYTHIDTAYKY--GIEDQVGRALTKKFSEGLKRESIFI-TTKLWNSYH 394 T AV A LE G+T IDTA+ Y G + + L + R I L+ + Sbjct: 27 TSAAVTRAFLERGHTEIDTAFVYSEGQSETILGGLGLRLGGSDCRVKIDTKAIPLFGNSL 86 Query: 395 EREQVIPALRKSLENLNLEYVDLYLIHWPIAMFENDTLLDNVDFLDTWRGMIDAKKLGLT 574 + + + L SL+ L VDL+ +H P ++ T ++ +T R + G Sbjct: 87 KPDSLRFQLETSLKRLQCPRVDLFYLHMP----DHSTPVE-----ETLRACHQLHQEGKF 137 Query: 575 KSIGISNFNQEQIQRII----DSGLEXPSALQIELNLNLQQ--PELFKFCRENDIVVMAY 736 +G+SN+ ++ I +G P+ Q N +Q ELF R + A+ Sbjct: 138 VELGLSNYAAWEVAEICTLCKSNGWILPTVYQGMYNAITRQVETELFPCLRHFGLRFYAF 197 Query: 737 TPF-GSLFPSK 766 P G L K Sbjct: 198 NPLAGGLLTGK 208 >AK092420-1|BAC03884.1| 357|Homo sapiens protein ( Homo sapiens cDNA FLJ35101 fis, clone PLACE6006418, weakly similar to PUTATIVE PRE-MRNA SPLICING FACTOR ATP-DEPENDENT RNA HELICASE. ). Length = 357 Score = 30.7 bits (66), Expect = 7.4 Identities = 15/40 (37%), Positives = 25/40 (62%) Frame = +2 Query: 548 IDAKKLGLTKSIGISNFNQEQIQRIIDSGLEXPSALQIEL 667 +DA+K+ +T + +F+ IQ +IDSGLE S + E+ Sbjct: 315 MDARKVVVTHWLADFSFSLPSIQHVIDSGLELRSVSEREI 354 >AF203447-1|AAG31422.1| 294|Homo sapiens sperm acrosome membrane protein SAMP32 protein. Length = 294 Score = 30.7 bits (66), Expect = 7.4 Identities = 17/56 (30%), Positives = 25/56 (44%) Frame = +2 Query: 83 CLSALCFTSADLIVPTLQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYA 250 C + L T L++ LQ + G N+ L H +G+ ND+E A YA Sbjct: 8 CSAGLLMTVGWLLLAGLQSARGTNVTAAVQDAGLAHEGEGEEETENNDSETAENYA 63 Database: human Posted date: Oct 23, 2007 1:18 PM Number of letters in database: 76,859,062 Number of sequences in database: 237,096 Lambda K H 0.318 0.134 0.401 Gapped Lambda K H 0.279 0.0580 0.190 Matrix: BLOSUM62 Gap Penalties: Existence: 9, Extension: 2 Number of Hits to DB: 131,130,359 Number of Sequences: 237096 Number of extensions: 3048644 Number of successful extensions: 11717 Number of sequences better than 10.0: 138 Number of HSP's better than 10.0 without gapping: 11080 Number of HSP's successfully gapped in prelim test: 0 Number of HSP's that attempted gapping in prelim test: 0 Number of HSP's gapped (non-prelim): 11441 length of database: 76,859,062 effective HSP length: 90 effective length of database: 55,520,422 effective search space used: 11437206932 frameshift window, decay const: 40, 0.1 T: 12 A: 40 X1: 16 ( 7.3 bits) X2: 37 (14.9 bits) X3: 62 (25.0 bits) S1: 41 (21.7 bits)
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