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Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= MFBP02_F_N07
         (899 letters)

Database: uniref50 
           1,657,284 sequences; 575,637,011 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

UniRef50_UPI00015B4325 Cluster: PREDICTED: similar to aconitase,...   206   4e-52
UniRef50_Q99798 Cluster: Aconitate hydratase, mitochondrial prec...   198   2e-49
UniRef50_Q9VIE8 Cluster: CG9244-PB; n=37; cellular organisms|Rep...   195   1e-48
UniRef50_Q0CSK9 Cluster: Aconitate hydratase, mitochondrial; n=2...   184   2e-45
UniRef50_P19414 Cluster: Aconitate hydratase, mitochondrial prec...   175   2e-42
UniRef50_O13966 Cluster: Aconitate hydratase, mitochondrial prec...   172   1e-41
UniRef50_Q4PB22 Cluster: Putative uncharacterized protein; n=5; ...   135   2e-30
UniRef50_Q4AHJ7 Cluster: Aconitate hydratase; n=1; Chlorobium ph...   128   3e-28
UniRef50_Q2UTF0 Cluster: Aconitase/homoaconitase; n=9; cellular ...   124   4e-27
UniRef50_Q0USA6 Cluster: Putative uncharacterized protein; n=2; ...   122   2e-26
UniRef50_A0RTP9 Cluster: 3-isopropylmalate isomerase/aconitase A...   106   9e-22
UniRef50_Q5AVN8 Cluster: Putative uncharacterized protein; n=1; ...    68   3e-10
UniRef50_Q5A379 Cluster: Putative uncharacterized protein; n=1; ...    49   1e-04
UniRef50_Q74AD1 Cluster: Aconitate hydratase, putative; n=12; Ba...    41   0.049
UniRef50_O67656 Cluster: Aconitase; n=17; cellular organisms|Rep...    41   0.049
UniRef50_Q7NDZ5 Cluster: Aconitate hydratase; n=28; Bacteria|Rep...    40   0.065
UniRef50_Q5V0F1 Cluster: Aconitate hydratase; n=8; cellular orga...    40   0.11 
UniRef50_A5ZNE1 Cluster: Putative uncharacterized protein; n=1; ...    35   2.5  
UniRef50_Q6BX71 Cluster: 5-aminolevulinate synthase, mitochondri...    35   2.5  
UniRef50_O75944 Cluster: Aconitase; n=34; cellular organisms|Rep...    34   4.3  
UniRef50_A0HK99 Cluster: Aconitate hydratase-like; n=3; Burkhold...    34   5.7  
UniRef50_Q9WYC7 Cluster: 3-isopropylmalate dehydratase large sub...    34   5.7  
UniRef50_Q58409 Cluster: 3-isopropylmalate dehydratase large sub...    34   5.7  
UniRef50_UPI0000498C9D Cluster: conserved hypothetical protein; ...    33   7.5  
UniRef50_A6G875 Cluster: 3-isopropylmalate dehydratase; n=1; Ple...    33   7.5  
UniRef50_Q5ULN8 Cluster: Orf76; n=1; Lactobacillus phage LP65|Re...    33   7.5  

>UniRef50_UPI00015B4325 Cluster: PREDICTED: similar to aconitase,
           mitochondrial; n=1; Nasonia vitripennis|Rep: PREDICTED:
           similar to aconitase, mitochondrial - Nasonia
           vitripennis
          Length = 917

 Score =  206 bits (504), Expect = 4e-52
 Identities = 100/127 (78%), Positives = 112/127 (88%)
 Frame = +2

Query: 386 STRYPXPYEKLTKNLEVVKKRLGRELTLSEKILYSHLDDPKGQEIERGASYLRLRPDRVA 565
           ST Y  PY+KL +N+++VKKRL R LTLSEKILYSHLD+P+ Q+I RG SYLRLRPDRVA
Sbjct: 173 STAY-LPYDKLDENIKIVKKRLDRPLTLSEKILYSHLDEPQKQDIVRGTSYLRLRPDRVA 231

Query: 566 MQDATAQMAMLQFISSGLPRVAVPSTIHCDHLIEAQVGGEKDLARAKDLNKEVYKFLETA 745
           MQDATAQMAMLQFISSGLPRVAVPSTIHCDHLIEAQ+GG+KDL RAKD+NKEVY FL+TA
Sbjct: 232 MQDATAQMAMLQFISSGLPRVAVPSTIHCDHLIEAQLGGDKDLKRAKDINKEVYSFLKTA 291

Query: 746 GANMESG 766
           GA    G
Sbjct: 292 GAKYGVG 298



 Score = 65.3 bits (152), Expect = 2e-09
 Identities = 31/41 (75%), Positives = 31/41 (75%)
 Frame = +3

Query: 774 PGSGIIHQIILENYASLXLLMIGTDSHTPNXXXXXXXCIGV 896
           PGSGIIHQIILENYA   LLMIGTDSHTPN       CIGV
Sbjct: 302 PGSGIIHQIILENYAFPGLLMIGTDSHTPNGGGLGGLCIGV 342



 Score = 47.6 bits (108), Expect = 4e-04
 Identities = 21/26 (80%), Positives = 24/26 (92%)
 Frame = +1

Query: 313 SEIQQRCFSVSPLTAAAAQVAMSKFD 390
           +E+QQRCFS SPLT AAA+VAMSKFD
Sbjct: 147 AEVQQRCFSTSPLTFAAAKVAMSKFD 172


>UniRef50_Q99798 Cluster: Aconitate hydratase, mitochondrial
           precursor; n=28; cellular organisms|Rep: Aconitate
           hydratase, mitochondrial precursor - Homo sapiens
           (Human)
          Length = 780

 Score =  198 bits (483), Expect = 2e-49
 Identities = 95/120 (79%), Positives = 103/120 (85%)
 Frame = +2

Query: 407 YEKLTKNLEVVKKRLGRELTLSEKILYSHLDDPKGQEIERGASYLRLRPDRVAMQDATAQ 586
           Y+ L KN+ +V+KRL R LTLSEKI+Y HLDDP  QEIERG SYLRLRPDRVAMQDATAQ
Sbjct: 45  YDLLEKNINIVRKRLNRPLTLSEKIVYGHLDDPASQEIERGKSYLRLRPDRVAMQDATAQ 104

Query: 587 MAMLQFISSGLPRVAVPSTIHCDHLIEAQVGGEKDLARAKDLNKEVYKFLETAGANMESG 766
           MAMLQFISSGL +VAVPSTIHCDHLIEAQVGGEKDL RAKD+N+EVY FL TAGA    G
Sbjct: 105 MAMLQFISSGLSKVAVPSTIHCDHLIEAQVGGEKDLRRAKDINQEVYNFLATAGAKYGVG 164



 Score = 63.3 bits (147), Expect = 8e-09
 Identities = 29/42 (69%), Positives = 32/42 (76%)
 Frame = +3

Query: 771 EPGSGIIHQIILENYASLXLLMIGTDSHTPNXXXXXXXCIGV 896
           +PGSGIIHQIILENYA   +L+IGTDSHTPN       CIGV
Sbjct: 167 KPGSGIIHQIILENYAYPGVLLIGTDSHTPNGGGLGGICIGV 208


>UniRef50_Q9VIE8 Cluster: CG9244-PB; n=37; cellular organisms|Rep:
           CG9244-PB - Drosophila melanogaster (Fruit fly)
          Length = 787

 Score =  195 bits (475), Expect = 1e-48
 Identities = 94/121 (77%), Positives = 102/121 (84%)
 Frame = +2

Query: 404 PYEKLTKNLEVVKKRLGRELTLSEKILYSHLDDPKGQEIERGASYLRLRPDRVAMQDATA 583
           PYEKL K LEVV+ RL R LTLSEK+LYSHLDDP  Q+I RG SYLRLRPDRVAMQDATA
Sbjct: 51  PYEKLNKRLEVVRGRLNRPLTLSEKVLYSHLDDPANQDIVRGTSYLRLRPDRVAMQDATA 110

Query: 584 QMAMLQFISSGLPRVAVPSTIHCDHLIEAQVGGEKDLARAKDLNKEVYKFLETAGANMES 763
           QMA+LQFISSGL +VAVPST+HCDHLIEAQ+GG KDLARAKDLNKEVY FL +  A    
Sbjct: 111 QMALLQFISSGLKKVAVPSTVHCDHLIEAQIGGPKDLARAKDLNKEVYDFLASTCAKYGL 170

Query: 764 G 766
           G
Sbjct: 171 G 171



 Score = 65.7 bits (153), Expect = 2e-09
 Identities = 31/42 (73%), Positives = 32/42 (76%)
 Frame = +3

Query: 771 EPGSGIIHQIILENYASLXLLMIGTDSHTPNXXXXXXXCIGV 896
           +PGSGIIHQIILENYA   LLMIGTDSHTPN       CIGV
Sbjct: 174 KPGSGIIHQIILENYAFPGLLMIGTDSHTPNGGGLGGLCIGV 215


>UniRef50_Q0CSK9 Cluster: Aconitate hydratase, mitochondrial; n=2;
           Pezizomycotina|Rep: Aconitate hydratase, mitochondrial -
           Aspergillus terreus (strain NIH 2624)
          Length = 781

 Score =  184 bits (449), Expect = 2e-45
 Identities = 83/118 (70%), Positives = 102/118 (86%)
 Frame = +2

Query: 413 KLTKNLEVVKKRLGRELTLSEKILYSHLDDPKGQEIERGASYLRLRPDRVAMQDATAQMA 592
           K+++NL++V++RL R LT +EK+LYSHLDDP GQ+IERG SYL+LRPDRVA QDATAQMA
Sbjct: 77  KMSENLDIVRRRLSRPLTYAEKVLYSHLDDPHGQDIERGVSYLKLRPDRVACQDATAQMA 136

Query: 593 MLQFISSGLPRVAVPSTIHCDHLIEAQVGGEKDLARAKDLNKEVYKFLETAGANMESG 766
           +LQF+S+G+P VA P+T+HCDHLIEAQVGGEKDLARA ++NKEVY FL TA A    G
Sbjct: 137 ILQFMSAGMPSVATPTTVHCDHLIEAQVGGEKDLARANEINKEVYDFLATATAKYNIG 194



 Score = 58.4 bits (135), Expect = 2e-07
 Identities = 28/42 (66%), Positives = 30/42 (71%)
 Frame = +3

Query: 771 EPGSGIIHQIILENYASLXLLMIGTDSHTPNXXXXXXXCIGV 896
           +PGSGIIHQI+LENYA    LMIGTDSHTPN        IGV
Sbjct: 197 KPGSGIIHQIVLENYAFPGGLMIGTDSHTPNAGGLAMAAIGV 238


>UniRef50_P19414 Cluster: Aconitate hydratase, mitochondrial
           precursor; n=41; cellular organisms|Rep: Aconitate
           hydratase, mitochondrial precursor - Saccharomyces
           cerevisiae (Baker's yeast)
          Length = 778

 Score =  175 bits (425), Expect = 2e-42
 Identities = 81/120 (67%), Positives = 98/120 (81%)
 Frame = +2

Query: 407 YEKLTKNLEVVKKRLGRELTLSEKILYSHLDDPKGQEIERGASYLRLRPDRVAMQDATAQ 586
           Y++  + L++V+KRL R  T +EKILY HLDDP GQ+I+RG SYL+LRPDRVA QDATAQ
Sbjct: 41  YKQNVETLDIVRKRLNRPFTYAEKILYGHLDDPHGQDIQRGVSYLKLRPDRVACQDATAQ 100

Query: 587 MAMLQFISSGLPRVAVPSTIHCDHLIEAQVGGEKDLARAKDLNKEVYKFLETAGANMESG 766
           MA+LQF+S+GLP+VA P T+HCDHLI+AQVGGEKDL RA DLNKEVY FL +A A    G
Sbjct: 101 MAILQFMSAGLPQVAKPVTVHCDHLIQAQVGGEKDLKRAIDLNKEVYDFLASATAKYNMG 160



 Score = 58.0 bits (134), Expect = 3e-07
 Identities = 27/42 (64%), Positives = 30/42 (71%)
 Frame = +3

Query: 771 EPGSGIIHQIILENYASLXLLMIGTDSHTPNXXXXXXXCIGV 896
           +PGSGIIHQI+LENYA    L+IGTDSHTPN        IGV
Sbjct: 163 KPGSGIIHQIVLENYAFPGALIIGTDSHTPNAGGLGQLAIGV 204


>UniRef50_O13966 Cluster: Aconitate hydratase, mitochondrial
           precursor; n=21; cellular organisms|Rep: Aconitate
           hydratase, mitochondrial precursor - Schizosaccharomyces
           pombe (Fission yeast)
          Length = 778

 Score =  172 bits (418), Expect = 1e-41
 Identities = 82/120 (68%), Positives = 94/120 (78%)
 Frame = +2

Query: 407 YEKLTKNLEVVKKRLGRELTLSEKILYSHLDDPKGQEIERGASYLRLRPDRVAMQDATAQ 586
           Y+++  NLE+VKKRL R LT SEKILY HLDDP  Q+IERG SYL+LRPDRVA QDATAQ
Sbjct: 41  YQRIKDNLEIVKKRLNRPLTYSEKILYGHLDDPVNQDIERGVSYLKLRPDRVACQDATAQ 100

Query: 587 MAMLQFISSGLPRVAVPSTIHCDHLIEAQVGGEKDLARAKDLNKEVYKFLETAGANMESG 766
           MA+LQF+S+G+P VAVP T+HCDHLIEA  GG  DL RA   NKEVY FL+TA A    G
Sbjct: 101 MAILQFMSAGMPEVAVPVTVHCDHLIEAYEGGPIDLERANVTNKEVYDFLQTACAKYNIG 160



 Score = 56.8 bits (131), Expect = 7e-07
 Identities = 27/41 (65%), Positives = 29/41 (70%)
 Frame = +3

Query: 774 PGSGIIHQIILENYASLXLLMIGTDSHTPNXXXXXXXCIGV 896
           PGSGIIHQI+LENYA    L+IGTDSHTPN        IGV
Sbjct: 164 PGSGIIHQIVLENYAFPGGLLIGTDSHTPNAGGLGMVAIGV 204


>UniRef50_Q4PB22 Cluster: Putative uncharacterized protein; n=5;
           Fungi/Metazoa group|Rep: Putative uncharacterized
           protein - Ustilago maydis (Smut fungus)
          Length = 1041

 Score =  135 bits (326), Expect = 2e-30
 Identities = 70/127 (55%), Positives = 93/127 (73%), Gaps = 8/127 (6%)
 Frame = +2

Query: 389 TRYPXPYEKLTKNLEVVKKRLGRELTLSEKILYSHLDDPK------GQEIE--RGASYLR 544
           +R P PY +L  NLE V+ +L R LTLSEKILYSHL +P+      G ++   RG  YL+
Sbjct: 148 SRVP-PYTELLTNLETVRAQLNRPLTLSEKILYSHLRNPEHDLAGVGADVSAIRGKKYLK 206

Query: 545 LRPDRVAMQDATAQMAMLQFISSGLPRVAVPSTIHCDHLIEAQVGGEKDLARAKDLNKEV 724
           L+ DR+AMQDA+AQMA+LQF++ GLPR A+PS++HCDHLI+A  G E DL R+   N+EV
Sbjct: 207 LKIDRLAMQDASAQMALLQFMTCGLPRTAIPSSVHCDHLIQAFEGAEADLKRSIASNQEV 266

Query: 725 YKFLETA 745
           + FLE+A
Sbjct: 267 FAFLESA 273



 Score = 61.7 bits (143), Expect = 2e-08
 Identities = 28/41 (68%), Positives = 31/41 (75%)
 Frame = +3

Query: 774 PGSGIIHQIILENYASLXLLMIGTDSHTPNXXXXXXXCIGV 896
           PGSGIIHQI+LENYA+  LLM+GTDSHTPN        IGV
Sbjct: 284 PGSGIIHQIVLENYAAPGLLMLGTDSHTPNASGLGCLAIGV 324


>UniRef50_Q4AHJ7 Cluster: Aconitate hydratase; n=1; Chlorobium
           phaeobacteroides BS1|Rep: Aconitate hydratase -
           Chlorobium phaeobacteroides BS1
          Length = 141

 Score =  128 bits (308), Expect = 3e-28
 Identities = 61/111 (54%), Positives = 80/111 (72%), Gaps = 1/111 (0%)
 Frame = +2

Query: 407 YEKLTKNLEVVKKRLGRELTLSEKILYSHLD-DPKGQEIERGASYLRLRPDRVAMQDATA 583
           YEK    ++  +  L + +TL+EKILY+HLD +      +RG SY+  RPDRVAMQDATA
Sbjct: 25  YEKFPGRVKAARALLNKPMTLAEKILYAHLDGELPSASFDRGNSYVDFRPDRVAMQDATA 84

Query: 584 QMAMLQFISSGLPRVAVPSTIHCDHLIEAQVGGEKDLARAKDLNKEVYKFL 736
           QMA+LQF+ +G P+ AV S++HCDHLI+A+ G E+DLA A   NKEVY FL
Sbjct: 85  QMALLQFMQAGKPQAAVSSSVHCDHLIQAKSGAEQDLANADFTNKEVYDFL 135


>UniRef50_Q2UTF0 Cluster: Aconitase/homoaconitase; n=9; cellular
           organisms|Rep: Aconitase/homoaconitase - Aspergillus
           oryzae
          Length = 806

 Score =  124 bits (298), Expect = 4e-27
 Identities = 66/118 (55%), Positives = 84/118 (71%), Gaps = 5/118 (4%)
 Frame = +2

Query: 407 YEKLTKNLEVVKKRLGRELTLSEKILYSHL---DDPKG--QEIERGASYLRLRPDRVAMQ 571
           Y +   NL+ V++   R LTL+EK+LYSHL   DD     QEI+RG + L LRPDRVA  
Sbjct: 49  YGEQLSNLDTVRQSSRRPLTLTEKLLYSHLIPSDDKVWSLQEIDRGKTILELRPDRVACH 108

Query: 572 DATAQMAMLQFISSGLPRVAVPSTIHCDHLIEAQVGGEKDLARAKDLNKEVYKFLETA 745
           DATA MA+LQFIS+GLPRVAVP+T+H DHLI ++ G E D+ RA   + EVY+FL +A
Sbjct: 109 DATATMALLQFISAGLPRVAVPTTVHGDHLIVSEKGAEPDMKRALTEHAEVYEFLSSA 166



 Score = 49.6 bits (113), Expect = 1e-04
 Identities = 24/42 (57%), Positives = 28/42 (66%)
 Frame = +3

Query: 771 EPGSGIIHQIILENYASLXLLMIGTDSHTPNXXXXXXXCIGV 896
           +PGSGIIH +I EN+A    L+IGTDSHTPN        IGV
Sbjct: 176 KPGSGIIHTVIFENHAVPGGLIIGTDSHTPNAGGLAMMGIGV 217


>UniRef50_Q0USA6 Cluster: Putative uncharacterized protein; n=2;
           Pezizomycotina|Rep: Putative uncharacterized protein -
           Phaeosphaeria nodorum (Septoria nodorum)
          Length = 781

 Score =  122 bits (293), Expect = 2e-26
 Identities = 68/131 (51%), Positives = 94/131 (71%), Gaps = 11/131 (8%)
 Frame = +2

Query: 386 STRYPXPYEKLTKNLEVVKKRLG--RELTLSEKILYSHLDDPK---------GQEIERGA 532
           S+R P PY KL   L  V++ LG  R LTL+EKILY+HL++P+         G++I RG 
Sbjct: 45  SSRTP-PYPKLLARLADVRRVLGSTRHLTLAEKILYAHLENPEESLLSNTNNGRDI-RGQ 102

Query: 533 SYLRLRPDRVAMQDATAQMAMLQFISSGLPRVAVPSTIHCDHLIEAQVGGEKDLARAKDL 712
           + L+L+PDRVAMQDA+AQMA+LQF+S GL + AVP++IHCDH+I  + G + DL ++   
Sbjct: 103 ANLKLKPDRVAMQDASAQMALLQFMSCGLGKTAVPASIHCDHMIVGEKGADLDLPQSIKG 162

Query: 713 NKEVYKFLETA 745
           NKEV+ FLE+A
Sbjct: 163 NKEVFDFLESA 173



 Score = 54.0 bits (124), Expect = 5e-06
 Identities = 23/41 (56%), Positives = 30/41 (73%)
 Frame = +3

Query: 774 PGSGIIHQIILENYASLXLLMIGTDSHTPNXXXXXXXCIGV 896
           PG+GIIHQ +LENY++  L+M+GTDSH+PN        IGV
Sbjct: 184 PGAGIIHQSVLENYSAPGLMMLGTDSHSPNAGGLGAIVIGV 224


>UniRef50_A0RTP9 Cluster: 3-isopropylmalate isomerase/aconitase A;
           n=7; cellular organisms|Rep: 3-isopropylmalate
           isomerase/aconitase A - Cenarchaeum symbiosum
          Length = 754

 Score =  106 bits (254), Expect = 9e-22
 Identities = 53/120 (44%), Positives = 74/120 (61%)
 Frame = +2

Query: 407 YEKLTKNLEVVKKRLGRELTLSEKILYSHLDDPKGQEIERGASYLRLRPDRVAMQDATAQ 586
           YE+L + ++  +K  GR LTLSEKI+  H+             Y+ L PDRVA+QD T Q
Sbjct: 14  YERLREGIDRYRKDAGRPLTLSEKIMAGHMVRDGTDIPVENKDYVHLTPDRVALQDVTGQ 73

Query: 587 MAMLQFISSGLPRVAVPSTIHCDHLIEAQVGGEKDLARAKDLNKEVYKFLETAGANMESG 766
           M MLQF+ +     A+P+TIHCDHLI A+V G +D+  + D N EV++FL++A A    G
Sbjct: 74  MVMLQFMVTRHEETALPTTIHCDHLIRAKVEGGEDMRVSLDENSEVFRFLKSAAARYGCG 133



 Score = 56.4 bits (130), Expect = 9e-07
 Identities = 25/42 (59%), Positives = 30/42 (71%)
 Frame = +3

Query: 771 EPGSGIIHQIILENYASLXLLMIGTDSHTPNXXXXXXXCIGV 896
           +PG+GIIHQ++LENYA    LMIGTDSHTPN        +GV
Sbjct: 136 KPGAGIIHQVVLENYAFPGGLMIGTDSHTPNAGGLGMIAVGV 177


>UniRef50_Q5AVN8 Cluster: Putative uncharacterized protein; n=1;
           Emericella nidulans|Rep: Putative uncharacterized
           protein - Emericella nidulans (Aspergillus nidulans)
          Length = 326

 Score = 68.1 bits (159), Expect = 3e-10
 Identities = 31/65 (47%), Positives = 45/65 (69%)
 Frame = +2

Query: 407 YEKLTKNLEVVKKRLGRELTLSEKILYSHLDDPKGQEIERGASYLRLRPDRVAMQDATAQ 586
           + K +  +  +++RL R LT +EK+LY+HLDD     I RG + LR +P R+A QDATAQ
Sbjct: 37  FSKFSSKIGTLRRRLKRPLTYAEKVLYNHLDDEFDGNIVRGQTQLRSKPVRIACQDATAQ 96

Query: 587 MAMLQ 601
           MA++Q
Sbjct: 97  MALIQ 101


>UniRef50_Q5A379 Cluster: Putative uncharacterized protein; n=1;
           Candida albicans|Rep: Putative uncharacterized protein -
           Candida albicans (Yeast)
          Length = 115

 Score = 49.2 bits (112), Expect = 1e-04
 Identities = 31/108 (28%), Positives = 53/108 (49%)
 Frame = -2

Query: 778 PGSRTXLHISSGSL*KLVYFFVEVLSPGQILLASDLGFDQVITMNGGRYSYTGKAGRDKL 599
           P ++     SSG   ++V F V+V   GQI   ++L  DQ++T++             KL
Sbjct: 9   PETQVIFGTSSGQ--EIVNFLVQVNGSGQIFWTTNLSLDQMVTVDSRWSGNLWNTSGHKL 66

Query: 598 *HCHLCSGVLHGHTVGTQAEITCAAFNFLSFGVIQVRI*DFLRQGQFS 455
            + HL   +L  + V +Q ++   +FNFL   +IQ+ +  F    Q+S
Sbjct: 67  QNGHLGGSILTSNPVWSQFQVRDTSFNFLVMRIIQMTVQKFFSISQWS 114


>UniRef50_Q74AD1 Cluster: Aconitate hydratase, putative; n=12;
           Bacteria|Rep: Aconitate hydratase, putative - Geobacter
           sulfurreducens
          Length = 645

 Score = 40.7 bits (91), Expect = 0.049
 Identities = 28/65 (43%), Positives = 39/65 (60%), Gaps = 1/65 (1%)
 Frame = +2

Query: 467 LSEKILYSHLDDPKGQEIERGASYLRLRPDRVAMQDATAQMAMLQFISSGLPRVAVP-ST 643
           L+ KIL +HL   KG E+  G   + L+ D   +QDAT  MAML+FI+ G+ RV V  + 
Sbjct: 5   LATKILEAHL--VKG-ELTPGTE-IALKIDHALLQDATGTMAMLEFIAMGVDRVKVELAA 60

Query: 644 IHCDH 658
            + DH
Sbjct: 61  QYIDH 65



 Score = 35.1 bits (77), Expect = 2.5
 Identities = 15/41 (36%), Positives = 22/41 (53%)
 Frame = +3

Query: 771 EPGSGIIHQIILENYASLXLLMIGTDSHTPNXXXXXXXCIG 893
           +PG+G+ HQ+ LE +      M+G DSHT +        IG
Sbjct: 94  KPGNGVSHQVHLERFGVPGRTMLGADSHTTSAAGLSMIAIG 134


>UniRef50_O67656 Cluster: Aconitase; n=17; cellular organisms|Rep:
           Aconitase - Aquifex aeolicus
          Length = 659

 Score = 40.7 bits (91), Expect = 0.049
 Identities = 19/47 (40%), Positives = 27/47 (57%)
 Frame = +3

Query: 753 IWSXVLEPGSGIIHQIILENYASLXLLMIGTDSHTPNXXXXXXXCIG 893
           IW  + +PG+GI HQ+ LE +A     ++G+DSHTP         IG
Sbjct: 91  IW--LSKPGNGICHQVHLERFAKPGKTLLGSDSHTPTAGGMGMLAIG 135


>UniRef50_Q7NDZ5 Cluster: Aconitate hydratase; n=28; Bacteria|Rep:
           Aconitate hydratase - Gloeobacter violaceus
          Length = 645

 Score = 40.3 bits (90), Expect = 0.065
 Identities = 28/67 (41%), Positives = 37/67 (55%), Gaps = 1/67 (1%)
 Frame = +2

Query: 461 LTLSEKILYSHLDDPKGQEIERGASYLRLRPDRVAMQDATAQMAMLQFISSGLPRVAVP- 637
           + L+ KIL +HL      E+  G S + +R D+   QDAT  MA LQF + GLPRV    
Sbjct: 1   MNLTCKILQAHL---MSGELRPG-SEIGIRIDQTLTQDATGTMAYLQFEAMGLPRVRTKL 56

Query: 638 STIHCDH 658
           S  + DH
Sbjct: 57  SVSYIDH 63



 Score = 36.7 bits (81), Expect = 0.81
 Identities = 16/40 (40%), Positives = 22/40 (55%)
 Frame = +3

Query: 774 PGSGIIHQIILENYASLXLLMIGTDSHTPNXXXXXXXCIG 893
           PG+GI HQ+  E +A     ++G+DSHTP         IG
Sbjct: 93  PGNGICHQVHRERFAVPAQTLLGSDSHTPTCGGLGMLAIG 132


>UniRef50_Q5V0F1 Cluster: Aconitate hydratase; n=8; cellular
           organisms|Rep: Aconitate hydratase - Haloarcula
           marismortui (Halobacterium marismortui)
          Length = 677

 Score = 39.5 bits (88), Expect = 0.11
 Identities = 17/40 (42%), Positives = 23/40 (57%)
 Frame = +3

Query: 774 PGSGIIHQIILENYASLXLLMIGTDSHTPNXXXXXXXCIG 893
           PG+GI H +  EN+A+    M+G+DSHTP         IG
Sbjct: 115 PGNGICHNVHKENFAAPGKTMLGSDSHTPTPGGLGELAIG 154


>UniRef50_A5ZNE1 Cluster: Putative uncharacterized protein; n=1;
           Ruminococcus obeum ATCC 29174|Rep: Putative
           uncharacterized protein - Ruminococcus obeum ATCC 29174
          Length = 416

 Score = 35.1 bits (77), Expect = 2.5
 Identities = 13/27 (48%), Positives = 18/27 (66%)
 Frame = +3

Query: 777 GSGIIHQIILENYASLXLLMIGTDSHT 857
           G G+ HQ+++ENY     L+ G DSHT
Sbjct: 97  GKGVCHQVMIENYVRPGELIFGADSHT 123


>UniRef50_Q6BX71 Cluster: 5-aminolevulinate synthase, mitochondrial
           precursor; n=4; cellular organisms|Rep:
           5-aminolevulinate synthase, mitochondrial precursor -
           Debaryomyces hansenii (Yeast) (Torulaspora hansenii)
          Length = 575

 Score = 35.1 bits (77), Expect = 2.5
 Identities = 16/61 (26%), Positives = 29/61 (47%)
 Frame = +2

Query: 545 LRPDRVAMQDATAQMAMLQFISSGLPRVAVPSTIHCDHLIEAQVGGEKDLARAKDLNKEV 724
           +R  R  +QD  AQ    +++ + L  + +P   +  H++   VG   D  +A DL  + 
Sbjct: 408 IRYQRSTLQDRIAQQTNTRYVKNNLTDIGIPVIPNPSHIVPVLVGNALDAKKASDLLLDK 467

Query: 725 Y 727
           Y
Sbjct: 468 Y 468


>UniRef50_O75944 Cluster: Aconitase; n=34; cellular organisms|Rep:
           Aconitase - Homo sapiens (Human)
          Length = 600

 Score = 34.3 bits (75), Expect = 4.3
 Identities = 16/29 (55%), Positives = 18/29 (62%)
 Frame = +3

Query: 810 NYASLXLLMIGTDSHTPNXXXXXXXCIGV 896
           NYA   +L+IGTDSHTPN        IGV
Sbjct: 1   NYAYPGVLLIGTDSHTPNGGGLGGISIGV 29


>UniRef50_A0HK99 Cluster: Aconitate hydratase-like; n=3;
           Burkholderiales|Rep: Aconitate hydratase-like -
           Comamonas testosteroni KF-1
          Length = 659

 Score = 33.9 bits (74), Expect = 5.7
 Identities = 15/39 (38%), Positives = 22/39 (56%)
 Frame = +3

Query: 780 SGIIHQIILENYASLXLLMIGTDSHTPNXXXXXXXCIGV 896
           +GI H ++ E YA    L++GTDSHTP+         G+
Sbjct: 325 AGISHAMMAECYALPGQLVVGTDSHTPHSGALGCVAFGI 363


>UniRef50_Q9WYC7 Cluster: 3-isopropylmalate dehydratase large
           subunit 1; n=8; cellular organisms|Rep:
           3-isopropylmalate dehydratase large subunit 1 -
           Thermotoga maritima
          Length = 418

 Score = 33.9 bits (74), Expect = 5.7
 Identities = 15/31 (48%), Positives = 18/31 (58%)
 Frame = +3

Query: 765 VLEPGSGIIHQIILENYASLXLLMIGTDSHT 857
           V + G GI HQI+ E Y     L+ G DSHT
Sbjct: 91  VFDAGDGISHQILAEKYVKPGDLVAGADSHT 121


>UniRef50_Q58409 Cluster: 3-isopropylmalate dehydratase large
           subunit 1; n=7; cellular organisms|Rep:
           3-isopropylmalate dehydratase large subunit 1 -
           Methanococcus jannaschii
          Length = 420

 Score = 33.9 bits (74), Expect = 5.7
 Identities = 14/27 (51%), Positives = 17/27 (62%)
 Frame = +3

Query: 777 GSGIIHQIILENYASLXLLMIGTDSHT 857
           G GI HQI+ ENY    + + G DSHT
Sbjct: 94  GEGICHQILAENYVLPNMFVAGGDSHT 120


>UniRef50_UPI0000498C9D Cluster: conserved hypothetical protein;
           n=1; Entamoeba histolytica HM-1:IMSS|Rep: conserved
           hypothetical protein - Entamoeba histolytica HM-1:IMSS
          Length = 905

 Score = 33.5 bits (73), Expect = 7.5
 Identities = 16/36 (44%), Positives = 24/36 (66%), Gaps = 3/36 (8%)
 Frame = +2

Query: 407 YEKLTKNLEVVKKRLGRELTLSE---KILYSHLDDP 505
           YE+  K +E +KK +GRELTL E   K+ Y +++ P
Sbjct: 667 YEESVKRVEELKKSIGRELTLKEQWYKVKYDYINIP 702


>UniRef50_A6G875 Cluster: 3-isopropylmalate dehydratase; n=1;
           Plesiocystis pacifica SIR-1|Rep: 3-isopropylmalate
           dehydratase - Plesiocystis pacifica SIR-1
          Length = 643

 Score = 33.5 bits (73), Expect = 7.5
 Identities = 14/38 (36%), Positives = 22/38 (57%)
 Frame = +3

Query: 783 GIIHQIILENYASLXLLMIGTDSHTPNXXXXXXXCIGV 896
           G+ H+I++E+YA    +++ TDSHTP          GV
Sbjct: 317 GVCHRIVVEDYARPGDIIVLTDSHTPTAGVMNAFAFGV 354


>UniRef50_Q5ULN8 Cluster: Orf76; n=1; Lactobacillus phage LP65|Rep:
           Orf76 - Lactobacillus phage LP65
          Length = 496

 Score = 33.5 bits (73), Expect = 7.5
 Identities = 22/74 (29%), Positives = 36/74 (48%), Gaps = 2/74 (2%)
 Frame = +2

Query: 560 VAMQDATAQMAMLQFISSGLPRVAVPSTIHCDHLIEAQVGGEKDLAR--AKDLNKEVYKF 733
           V ++D  A  A+L+    G  R+A  +    D + +  +GG K+ A   AKD NK+ Y +
Sbjct: 119 VYIKDKLASAAILEEAGKGNERLAERTQKAMDDINDIDIGGNKNPAINIAKDFNKKAYFY 178

Query: 734 LETAGANMESGSGT 775
                  ++SG  T
Sbjct: 179 KHDYEGRIKSGLST 192


  Database: uniref50
    Posted date:  Oct 5, 2007 11:19 AM
  Number of letters in database: 575,637,011
  Number of sequences in database:  1,657,284
  
Lambda     K      H
   0.318    0.134    0.401 

Gapped
Lambda     K      H
   0.279   0.0580    0.190 


Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 862,654,542
Number of Sequences: 1657284
Number of extensions: 17377845
Number of successful extensions: 40334
Number of sequences better than 10.0: 27
Number of HSP's better than 10.0 without gapping: 38938
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 40323
length of database: 575,637,011
effective HSP length: 100
effective length of database: 409,908,611
effective search space used: 81571813589
frameshift window, decay const: 40,  0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)

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