Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= MFBP02_F_K09
(910 letters)
Database: uniref50
1,657,284 sequences; 575,637,011 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
UniRef50_UPI0000D55F1F Cluster: PREDICTED: similar to CG33113-PF... 115 2e-24
UniRef50_Q17NG9 Cluster: Reticulon/nogo; n=2; Endopterygota|Rep:... 109 7e-23
UniRef50_Q4G5V7 Cluster: Reticulon 5-a1; n=12; Danio rerio|Rep: ... 109 1e-22
UniRef50_Q9VMV9 Cluster: CG33113-PF, isoform F; n=11; Endopteryg... 109 1e-22
UniRef50_Q29L12 Cluster: GA17292-PA; n=1; Drosophila pseudoobscu... 109 1e-22
UniRef50_Q4G5X5 Cluster: Reticulon 1-A1; n=3; Tetraodontidae|Rep... 109 1e-22
UniRef50_UPI0000EB300C Cluster: reticulon 1; n=1; Canis lupus fa... 107 3e-22
UniRef50_Q16799 Cluster: Reticulon-1; n=53; Euteleostomi|Rep: Re... 107 4e-22
UniRef50_Q4G5W7 Cluster: Reticulon 1-a1; n=3; Danio rerio|Rep: R... 107 5e-22
UniRef50_Q7L7Q6 Cluster: RTN4; n=42; Tetrapoda|Rep: RTN4 - Homo ... 106 9e-22
UniRef50_Q9NQC3 Cluster: Reticulon-4; n=72; Euteleostomi|Rep: Re... 106 9e-22
UniRef50_Q4FZ68 Cluster: RTN4-L; n=6; Euteleostei|Rep: RTN4-L - ... 105 1e-21
UniRef50_Q4S2Q0 Cluster: Chromosome 17 SCAF14760, whole genome s... 105 2e-21
UniRef50_Q4G5W2 Cluster: Reticulon 4-l; n=3; Danio rerio|Rep: Re... 104 3e-21
UniRef50_Q6JRV1 Cluster: RTN4.1-A2; n=11; Xenopus|Rep: RTN4.1-A2... 98 3e-19
UniRef50_Q4T187 Cluster: Chromosome undetermined SCAF10698, whol... 97 5e-19
UniRef50_O95197 Cluster: Reticulon-3; n=77; Euteleostomi|Rep: Re... 94 5e-18
UniRef50_Q9ES97 Cluster: Reticulon-3; n=7; Murinae|Rep: Reticulo... 93 7e-18
UniRef50_Q4G5V0 Cluster: Reticulon 6-a1; n=22; Danio rerio|Rep: ... 92 2e-17
UniRef50_UPI0000E4A8E3 Cluster: PREDICTED: similar to reticulon ... 91 4e-17
UniRef50_A7SZV0 Cluster: Predicted protein; n=1; Nematostella ve... 78 3e-13
UniRef50_Q7RTJ4 Cluster: RTN-B2; n=11; Ciona intestinalis|Rep: R... 77 8e-13
UniRef50_O75298 Cluster: Reticulon-2; n=8; Mammalia|Rep: Reticul... 73 1e-11
UniRef50_O70622 Cluster: Reticulon-2; n=20; Eutheria|Rep: Reticu... 73 1e-11
UniRef50_Q4FZ76 Cluster: RTN2-A; n=7; Xenopus|Rep: RTN2-A - Xeno... 71 4e-11
UniRef50_Q4TTE6 Cluster: Reticulon; n=7; Caenorhabditis|Rep: Ret... 61 4e-08
UniRef50_UPI000155BB4D Cluster: PREDICTED: similar to RTN2 prote... 58 3e-07
UniRef50_Q4G5T7 Cluster: Reticulon 8-c; n=6; Clupeocephala|Rep: ... 55 3e-06
UniRef50_A7SJN6 Cluster: Predicted protein; n=1; Nematostella ve... 54 7e-06
UniRef50_Q4G5K8 Cluster: Reticulon 2c; n=6; Clupeocephala|Rep: R... 52 2e-05
UniRef50_Q5DE04 Cluster: SJCHGC02814 protein; n=1; Schistosoma j... 45 0.003
UniRef50_Q24199 Cluster: Tropomyosin-like protein; n=2; Drosophi... 41 0.050
UniRef50_UPI0000E822BE Cluster: PREDICTED: similar to RTN3w; n=1... 39 0.20
UniRef50_Q5DDK2 Cluster: SJCHGC06495 protein; n=1; Schistosoma j... 37 0.62
UniRef50_Q55HN1 Cluster: Putative uncharacterized protein; n=3; ... 34 4.4
>UniRef50_UPI0000D55F1F Cluster: PREDICTED: similar to CG33113-PF,
isoform F; n=1; Tribolium castaneum|Rep: PREDICTED:
similar to CG33113-PF, isoform F - Tribolium castaneum
Length = 479
Score = 115 bits (276), Expect = 2e-24
Identities = 64/141 (45%), Positives = 74/141 (52%)
Frame = +1
Query: 121 GPVESLIYWRNXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXFRLYKNVLQ 300
G VESLIYWR+ FR+YKN++Q
Sbjct: 286 GLVESLIYWRDPKKSGPVFGGVLLVLLALTYFSLISVVAYLSLLGLTGTISFRIYKNIVQ 345
Query: 301 AVQKTNDGHPFKWLLEAEVSVSXXXXXXXXXXXXXXXXXXXYELRRLFLVEDLVDSLKFG 480
AVQKT DGHPFK LLE +VS+ ELRRLFLVEDLVDS+KFG
Sbjct: 346 AVQKTGDGHPFKDLLEFDVSLPQEKVKEVSEVAVAHINAAVVELRRLFLVEDLVDSIKFG 405
Query: 481 VLLWCLTYVGACFNGITLIIL 543
VLLW LTY+GA FNG+TLII+
Sbjct: 406 VLLWTLTYLGAWFNGMTLIII 426
Score = 58.8 bits (136), Expect = 2e-07
Identities = 26/50 (52%), Positives = 35/50 (70%)
Frame = +2
Query: 551 IALFTLXKAYEMNKAQVDANLELAXAKINXITAKVRAAVPLGXXAXGXXD 700
+ALF+L K YE NK Q+DANLE+ K+ IT+KV+AA+P+G A D
Sbjct: 429 VALFSLPKVYETNKTQIDANLEIVRTKLAEITSKVKAAIPIGKKAEEKKD 478
>UniRef50_Q17NG9 Cluster: Reticulon/nogo; n=2; Endopterygota|Rep:
Reticulon/nogo - Aedes aegypti (Yellowfever mosquito)
Length = 493
Score = 109 bits (263), Expect = 7e-23
Identities = 59/139 (42%), Positives = 74/139 (53%)
Frame = +1
Query: 127 VESLIYWRNXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXFRLYKNVLQAV 306
VESLIYWR+ FR+YKNVLQAV
Sbjct: 302 VESLIYWRDVKKSGAVFGAGLTILIAMSLFSLISVFSYVSLLALFGTVSFRIYKNVLQAV 361
Query: 307 QKTNDGHPFKWLLEAEVSVSXXXXXXXXXXXXXXXXXXXYELRRLFLVEDLVDSLKFGVL 486
QKT++GHPFK L+ ++++S ELRRLFLVEDLVDS+KFGV+
Sbjct: 362 QKTSEGHPFKEYLDTDLTLSQEKVQQLSTVAVAHVNALLTELRRLFLVEDLVDSIKFGVV 421
Query: 487 LWCLTYVGACFNGITLIIL 543
L+CLTYVGA FNG+T +I+
Sbjct: 422 LYCLTYVGAIFNGMTCVII 440
Score = 52.8 bits (121), Expect = 1e-05
Identities = 25/50 (50%), Positives = 33/50 (66%)
Frame = +2
Query: 551 IALFTLXKAYEMNKAQVDANLELAXAKINXITAKVRAAVPLGXXAXGXXD 700
+ALFTL K YE NK +DA LEL +KI ++ K++AAVP+G A D
Sbjct: 443 VALFTLPKVYENNKQSIDAYLELVRSKILEVSDKIKAAVPIGKKAETEKD 492
>UniRef50_Q4G5V7 Cluster: Reticulon 5-a1; n=12; Danio rerio|Rep:
Reticulon 5-a1 - Danio rerio (Zebrafish) (Brachydanio
rerio)
Length = 818
Score = 109 bits (262), Expect = 1e-22
Identities = 54/94 (57%), Positives = 66/94 (70%)
Frame = +1
Query: 274 FRLYKNVLQAVQKTNDGHPFKWLLEAEVSVSXXXXXXXXXXXXXXXXXXXYELRRLFLVE 453
FR+YK+VLQAVQKT++GHPFK LE E+S+S ELRRLFLV+
Sbjct: 681 FRVYKSVLQAVQKTDEGHPFKSYLEVEISLSADQISKYVDKTQLYINTTMKELRRLFLVQ 740
Query: 454 DLVDSLKFGVLLWCLTYVGACFNGITLIILXLDS 555
DLVDS+KF VL+W LTYVGA FNG+TL+IL + S
Sbjct: 741 DLVDSIKFAVLMWLLTYVGALFNGLTLLILAVIS 774
>UniRef50_Q9VMV9 Cluster: CG33113-PF, isoform F; n=11;
Endopterygota|Rep: CG33113-PF, isoform F - Drosophila
melanogaster (Fruit fly)
Length = 595
Score = 109 bits (262), Expect = 1e-22
Identities = 63/168 (37%), Positives = 84/168 (50%), Gaps = 1/168 (0%)
Frame = +1
Query: 43 KXLTQSPWHARVQTPRFTSQADLPPR-GPVESLIYWRNXXXXXXXXXXXXXXXXXXXXXX 219
K + +P + P+ S ++ + G VESLIYWR+
Sbjct: 370 KVVPVAPVESTQPQPKIASVEEIFCKYGLVESLIYWRDVKKSGIVFGAGLITLAAISSFS 429
Query: 220 XXXXXXXXXXXXXXXXXXFRLYKNVLQAVQKTNDGHPFKWLLEAEVSVSXXXXXXXXXXX 399
FR+YK+V QAVQKTN+GHPFK LE ++++S
Sbjct: 430 VISVFAYLSLLTLFGTVAFRIYKSVTQAVQKTNEGHPFKDYLELDLTLSHEKVQNIAGVA 489
Query: 400 XXXXXXXXYELRRLFLVEDLVDSLKFGVLLWCLTYVGACFNGITLIIL 543
ELRRLFLVED++DS+KFGV+LW TYVGA FNG+TL+IL
Sbjct: 490 VAHINGFISELRRLFLVEDIIDSIKFGVILWVFTYVGAWFNGMTLVIL 537
Score = 50.4 bits (115), Expect = 6e-05
Identities = 20/42 (47%), Positives = 30/42 (71%)
Frame = +2
Query: 551 IALFTLXKAYEMNKAQVDANLELAXAKINXITAKVRAAVPLG 676
++LFTL K YE NK +D +L+L +K+ IT K+R A+P+G
Sbjct: 540 VSLFTLPKVYENNKQSIDTHLDLVRSKLTEITDKIRVAIPIG 581
>UniRef50_Q29L12 Cluster: GA17292-PA; n=1; Drosophila
pseudoobscura|Rep: GA17292-PA - Drosophila pseudoobscura
(Fruit fly)
Length = 547
Score = 109 bits (262), Expect = 1e-22
Identities = 59/141 (41%), Positives = 73/141 (51%)
Frame = +1
Query: 121 GPVESLIYWRNXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXFRLYKNVLQ 300
G VESLIYWR+ FR+YK+V Q
Sbjct: 349 GLVESLIYWRDVKKSGIVFGAGLITLVAISSFSVISVFAYLSLLALFGTVAFRIYKSVTQ 408
Query: 301 AVQKTNDGHPFKWLLEAEVSVSXXXXXXXXXXXXXXXXXXXYELRRLFLVEDLVDSLKFG 480
AVQKT+DGHPFK LE ++++S ELRRLFLVEDL+DS+KFG
Sbjct: 409 AVQKTSDGHPFKEYLELDLTLSQEKVQNIAGVAVAHINGFTAELRRLFLVEDLIDSIKFG 468
Query: 481 VLLWCLTYVGACFNGITLIIL 543
V+LW TY+GA FNG+TL+IL
Sbjct: 469 VILWVFTYIGAWFNGMTLVIL 489
Score = 49.2 bits (112), Expect = 1e-04
Identities = 20/42 (47%), Positives = 29/42 (69%)
Frame = +2
Query: 551 IALFTLXKAYEMNKAQVDANLELAXAKINXITAKVRAAVPLG 676
++LFTL K YE NK +D L+L +K+ IT K+R A+P+G
Sbjct: 492 VSLFTLPKVYENNKQSIDTYLDLVRSKLTEITDKIRVAIPIG 533
>UniRef50_Q4G5X5 Cluster: Reticulon 1-A1; n=3; Tetraodontidae|Rep:
Reticulon 1-A1 - Fugu rubripes (Japanese pufferfish)
(Takifugu rubripes)
Length = 729
Score = 109 bits (261), Expect = 1e-22
Identities = 54/94 (57%), Positives = 66/94 (70%)
Frame = +1
Query: 274 FRLYKNVLQAVQKTNDGHPFKWLLEAEVSVSXXXXXXXXXXXXXXXXXXXYELRRLFLVE 453
FR+YK+VLQAVQKT++GHPFK LE E+++S ELRRLFLV+
Sbjct: 591 FRIYKSVLQAVQKTDEGHPFKSYLEMEITLSQDQISKYADKILLYSNTCVKELRRLFLVQ 650
Query: 454 DLVDSLKFGVLLWCLTYVGACFNGITLIILXLDS 555
DLVDSLKF VL+W LTYVGA FNG+TL+IL + S
Sbjct: 651 DLVDSLKFAVLMWLLTYVGALFNGLTLLILAVVS 684
Score = 35.1 bits (77), Expect = 2.5
Identities = 12/40 (30%), Positives = 25/40 (62%)
Frame = +2
Query: 551 IALFTLXKAYEMNKAQVDANLELAXAKINXITAKVRAAVP 670
+++FT+ YE ++AQ+D + L +N + K++A +P
Sbjct: 683 VSMFTMPVVYEKHQAQIDQYVGLIRTHVNSVVGKIQAKIP 722
>UniRef50_UPI0000EB300C Cluster: reticulon 1; n=1; Canis lupus
familiaris|Rep: reticulon 1 - Canis familiaris
Length = 689
Score = 107 bits (258), Expect = 3e-22
Identities = 52/94 (55%), Positives = 66/94 (70%)
Frame = +1
Query: 274 FRLYKNVLQAVQKTNDGHPFKWLLEAEVSVSXXXXXXXXXXXXXXXXXXXYELRRLFLVE 453
FR+YK+VLQAVQKT++GHPFK LE E+++S ELRRLFLV+
Sbjct: 551 FRIYKSVLQAVQKTDEGHPFKTYLELEITLSQEQIQKYTDCLQFYVNNTLKELRRLFLVQ 610
Query: 454 DLVDSLKFGVLLWCLTYVGACFNGITLIILXLDS 555
DLVDSLKF VL+W LTYVGA FNG+TL+++ + S
Sbjct: 611 DLVDSLKFAVLMWLLTYVGALFNGLTLLLMAVVS 644
Score = 36.7 bits (81), Expect = 0.82
Identities = 15/40 (37%), Positives = 25/40 (62%)
Frame = +2
Query: 551 IALFTLXKAYEMNKAQVDANLELAXAKINXITAKVRAAVP 670
+++FTL Y ++AQ+D L L IN + AK++A +P
Sbjct: 643 VSMFTLPVVYVKHQAQIDQYLGLVRTHINTVVAKIQAKIP 682
>UniRef50_Q16799 Cluster: Reticulon-1; n=53; Euteleostomi|Rep:
Reticulon-1 - Homo sapiens (Human)
Length = 776
Score = 107 bits (257), Expect = 4e-22
Identities = 52/94 (55%), Positives = 66/94 (70%)
Frame = +1
Query: 274 FRLYKNVLQAVQKTNDGHPFKWLLEAEVSVSXXXXXXXXXXXXXXXXXXXYELRRLFLVE 453
FR+YK+VLQAVQKT++GHPFK LE E+++S ELRRLFLV+
Sbjct: 638 FRIYKSVLQAVQKTDEGHPFKAYLELEITLSQEQIQKYTDCLQFYVNSTLKELRRLFLVQ 697
Query: 454 DLVDSLKFGVLLWCLTYVGACFNGITLIILXLDS 555
DLVDSLKF VL+W LTYVGA FNG+TL+++ + S
Sbjct: 698 DLVDSLKFAVLMWLLTYVGALFNGLTLLLMAVVS 731
Score = 36.7 bits (81), Expect = 0.82
Identities = 15/40 (37%), Positives = 25/40 (62%)
Frame = +2
Query: 551 IALFTLXKAYEMNKAQVDANLELAXAKINXITAKVRAAVP 670
+++FTL Y ++AQ+D L L IN + AK++A +P
Sbjct: 730 VSMFTLPVVYVKHQAQIDQYLGLVRTHINAVVAKIQAKIP 769
>UniRef50_Q4G5W7 Cluster: Reticulon 1-a1; n=3; Danio rerio|Rep:
Reticulon 1-a1 - Danio rerio (Zebrafish) (Brachydanio
rerio)
Length = 767
Score = 107 bits (256), Expect = 5e-22
Identities = 52/90 (57%), Positives = 64/90 (71%)
Frame = +1
Query: 274 FRLYKNVLQAVQKTNDGHPFKWLLEAEVSVSXXXXXXXXXXXXXXXXXXXYELRRLFLVE 453
FR+YK+VLQAVQKT++GHPFK L+ E+S+S ELRRLFLV+
Sbjct: 629 FRVYKSVLQAVQKTDEGHPFKVYLDVEMSLSHDQMQKYAENVQYYINSTLKELRRLFLVQ 688
Query: 454 DLVDSLKFGVLLWCLTYVGACFNGITLIIL 543
DLVDSLKF VL+W LTYVGA FNG+TL+I+
Sbjct: 689 DLVDSLKFAVLMWLLTYVGALFNGLTLLIM 718
Score = 34.3 bits (75), Expect = 4.4
Identities = 12/40 (30%), Positives = 25/40 (62%)
Frame = +2
Query: 551 IALFTLXKAYEMNKAQVDANLELAXAKINXITAKVRAAVP 670
+ +F++ YE +AQ+D ++L ++N + AK++ VP
Sbjct: 721 VCMFSMPVVYEKYQAQIDQYVDLIRTQVNSVVAKIQEKVP 760
>UniRef50_Q7L7Q6 Cluster: RTN4; n=42; Tetrapoda|Rep: RTN4 - Homo
sapiens (Human)
Length = 373
Score = 106 bits (254), Expect = 9e-22
Identities = 51/94 (54%), Positives = 65/94 (69%)
Frame = +1
Query: 274 FRLYKNVLQAVQKTNDGHPFKWLLEAEVSVSXXXXXXXXXXXXXXXXXXXYELRRLFLVE 453
FR+YK V+QA+QK+++GHPF+ LE+EV++S ELRRLFLV+
Sbjct: 235 FRIYKGVIQAIQKSDEGHPFRAYLESEVAISEELVQKYSNSALGHVNCTIKELRRLFLVD 294
Query: 454 DLVDSLKFGVLLWCLTYVGACFNGITLIILXLDS 555
DLVDSLKF VL+W TYVGA FNG+TL+IL L S
Sbjct: 295 DLVDSLKFAVLMWVFTYVGALFNGLTLLILALIS 328
Score = 33.9 bits (74), Expect = 5.8
Identities = 15/40 (37%), Positives = 25/40 (62%)
Frame = +2
Query: 551 IALFTLXKAYEMNKAQVDANLELAXAKINXITAKVRAAVP 670
I+LF++ YE ++AQ+D L LA + AK++A +P
Sbjct: 327 ISLFSVPVIYERHQAQIDHYLGLANKNVKDAMAKIQAKIP 366
>UniRef50_Q9NQC3 Cluster: Reticulon-4; n=72; Euteleostomi|Rep:
Reticulon-4 - Homo sapiens (Human)
Length = 1192
Score = 106 bits (254), Expect = 9e-22
Identities = 51/94 (54%), Positives = 65/94 (69%)
Frame = +1
Query: 274 FRLYKNVLQAVQKTNDGHPFKWLLEAEVSVSXXXXXXXXXXXXXXXXXXXYELRRLFLVE 453
FR+YK V+QA+QK+++GHPF+ LE+EV++S ELRRLFLV+
Sbjct: 1054 FRIYKGVIQAIQKSDEGHPFRAYLESEVAISEELVQKYSNSALGHVNCTIKELRRLFLVD 1113
Query: 454 DLVDSLKFGVLLWCLTYVGACFNGITLIILXLDS 555
DLVDSLKF VL+W TYVGA FNG+TL+IL L S
Sbjct: 1114 DLVDSLKFAVLMWVFTYVGALFNGLTLLILALIS 1147
Score = 33.9 bits (74), Expect = 5.8
Identities = 15/40 (37%), Positives = 25/40 (62%)
Frame = +2
Query: 551 IALFTLXKAYEMNKAQVDANLELAXAKINXITAKVRAAVP 670
I+LF++ YE ++AQ+D L LA + AK++A +P
Sbjct: 1146 ISLFSVPVIYERHQAQIDHYLGLANKNVKDAMAKIQAKIP 1185
>UniRef50_Q4FZ68 Cluster: RTN4-L; n=6; Euteleostei|Rep: RTN4-L -
Oncorhynchus mykiss (Rainbow trout) (Salmo gairdneri)
Length = 383
Score = 105 bits (253), Expect = 1e-21
Identities = 51/92 (55%), Positives = 63/92 (68%)
Frame = +1
Query: 274 FRLYKNVLQAVQKTNDGHPFKWLLEAEVSVSXXXXXXXXXXXXXXXXXXXYELRRLFLVE 453
FR+YK +LQA+QK+++GHPFK L+ +V++S ELRRLFLVE
Sbjct: 244 FRIYKGILQAIQKSDEGHPFKLYLDQDVALSEGTVHKYSDCVLARFNTTVTELRRLFLVE 303
Query: 454 DLVDSLKFGVLLWCLTYVGACFNGITLIILXL 549
DLVDSLKF VL+W LTYVGA FNG+TL IL L
Sbjct: 304 DLVDSLKFAVLMWILTYVGALFNGLTLFILGL 335
>UniRef50_Q4S2Q0 Cluster: Chromosome 17 SCAF14760, whole genome
shotgun sequence; n=2; Tetraodon nigroviridis|Rep:
Chromosome 17 SCAF14760, whole genome shotgun sequence -
Tetraodon nigroviridis (Green puffer)
Length = 991
Score = 105 bits (251), Expect = 2e-21
Identities = 50/92 (54%), Positives = 63/92 (68%)
Frame = +1
Query: 274 FRLYKNVLQAVQKTNDGHPFKWLLEAEVSVSXXXXXXXXXXXXXXXXXXXYELRRLFLVE 453
FR+YK +LQA+QK+++GHPF+ LE EV++S E+RRLFLVE
Sbjct: 853 FRIYKGILQAIQKSDEGHPFRQYLEEEVALSEEVVHKYSDLVLAKLNRSVAEVRRLFLVE 912
Query: 454 DLVDSLKFGVLLWCLTYVGACFNGITLIILXL 549
DLVDSLKF L+W LTYVGA FNG+TL+IL L
Sbjct: 913 DLVDSLKFAALMWILTYVGALFNGLTLLILGL 944
>UniRef50_Q4G5W2 Cluster: Reticulon 4-l; n=3; Danio rerio|Rep:
Reticulon 4-l - Danio rerio (Zebrafish) (Brachydanio
rerio)
Length = 322
Score = 104 bits (250), Expect = 3e-21
Identities = 51/90 (56%), Positives = 60/90 (66%)
Frame = +1
Query: 274 FRLYKNVLQAVQKTNDGHPFKWLLEAEVSVSXXXXXXXXXXXXXXXXXXXYELRRLFLVE 453
FR+YK +LQAVQK+ DGHPFK L+ + ++ ELRRLFLVE
Sbjct: 184 FRIYKGILQAVQKSEDGHPFKMYLDKDTALPAEMVHKYSDSTLVHINTVIKELRRLFLVE 243
Query: 454 DLVDSLKFGVLLWCLTYVGACFNGITLIIL 543
DLVDSLKF VL+W LTYVGA FNG+TLIIL
Sbjct: 244 DLVDSLKFAVLMWILTYVGALFNGLTLIIL 273
>UniRef50_Q6JRV1 Cluster: RTN4.1-A2; n=11; Xenopus|Rep: RTN4.1-A2 -
Xenopus laevis (African clawed frog)
Length = 1055
Score = 97.9 bits (233), Expect = 3e-19
Identities = 46/93 (49%), Positives = 61/93 (65%)
Frame = +1
Query: 277 RLYKNVLQAVQKTNDGHPFKWLLEAEVSVSXXXXXXXXXXXXXXXXXXXYELRRLFLVED 456
R+YK +LQA+QK+ +GHPF+ +LE+ ++V ELR LFLVED
Sbjct: 918 RIYKGILQAIQKSEEGHPFRSILESNLAVPEDLVQKYCNVALNHVNCTVKELRHLFLVED 977
Query: 457 LVDSLKFGVLLWCLTYVGACFNGITLIILXLDS 555
LVDSLKF VL+W TY+GA FNG+TL+I+ L S
Sbjct: 978 LVDSLKFAVLMWVFTYIGALFNGLTLLIVALIS 1010
>UniRef50_Q4T187 Cluster: Chromosome undetermined SCAF10698, whole
genome shotgun sequence; n=1; Tetraodon
nigroviridis|Rep: Chromosome undetermined SCAF10698,
whole genome shotgun sequence - Tetraodon nigroviridis
(Green puffer)
Length = 214
Score = 97.1 bits (231), Expect = 5e-19
Identities = 45/90 (50%), Positives = 61/90 (67%)
Frame = +1
Query: 274 FRLYKNVLQAVQKTNDGHPFKWLLEAEVSVSXXXXXXXXXXXXXXXXXXXYELRRLFLVE 453
FR+YK+V+QAVQK++DGHPF+ LL+ ++SVS + RRL LVE
Sbjct: 74 FRVYKSVIQAVQKSDDGHPFRSLLDRDISVSSEWIRALADQSLVYVNWFVSQTRRLILVE 133
Query: 454 DLVDSLKFGVLLWCLTYVGACFNGITLIIL 543
DLVDSLK ++W +TYVGA FNG+TL+I+
Sbjct: 134 DLVDSLKVATVMWVMTYVGAIFNGVTLLII 163
>UniRef50_O95197 Cluster: Reticulon-3; n=77; Euteleostomi|Rep:
Reticulon-3 - Homo sapiens (Human)
Length = 1032
Score = 93.9 bits (223), Expect = 5e-18
Identities = 45/90 (50%), Positives = 59/90 (65%)
Frame = +1
Query: 274 FRLYKNVLQAVQKTNDGHPFKWLLEAEVSVSXXXXXXXXXXXXXXXXXXXYELRRLFLVE 453
FR+YK+V+QAVQK+ +GHPFK L+ ++++S + RLFLVE
Sbjct: 893 FRIYKSVIQAVQKSEEGHPFKAYLDVDITLSSEAFHNYMNAAMVHINRALKLIIRLFLVE 952
Query: 454 DLVDSLKFGVLLWCLTYVGACFNGITLIIL 543
DLVDSLK V +W +TYVGA FNGITL+IL
Sbjct: 953 DLVDSLKLAVFMWLMTYVGAVFNGITLLIL 982
>UniRef50_Q9ES97 Cluster: Reticulon-3; n=7; Murinae|Rep: Reticulon-3 -
Mus musculus (Mouse)
Length = 964
Score = 93.5 bits (222), Expect = 7e-18
Identities = 45/90 (50%), Positives = 59/90 (65%)
Frame = +1
Query: 274 FRLYKNVLQAVQKTNDGHPFKWLLEAEVSVSXXXXXXXXXXXXXXXXXXXYELRRLFLVE 453
FR+YK+V+QAVQK+ +GHPFK L+ ++++S + RLFLVE
Sbjct: 825 FRVYKSVIQAVQKSEEGHPFKAYLDVDITLSSEAFHNYMNAAMVHVNKALKLIIRLFLVE 884
Query: 454 DLVDSLKFGVLLWCLTYVGACFNGITLIIL 543
DLVDSLK V +W +TYVGA FNGITL+IL
Sbjct: 885 DLVDSLKLAVFMWLMTYVGAVFNGITLLIL 914
>UniRef50_Q4G5V0 Cluster: Reticulon 6-a1; n=22; Danio rerio|Rep:
Reticulon 6-a1 - Danio rerio (Zebrafish) (Brachydanio
rerio)
Length = 875
Score = 92.3 bits (219), Expect = 2e-17
Identities = 48/94 (51%), Positives = 59/94 (62%)
Frame = +1
Query: 277 RLYKNVLQAVQKTNDGHPFKWLLEAEVSVSXXXXXXXXXXXXXXXXXXXYELRRLFLVED 456
R++ VLQA++KT DGHPF+ LE +V +S ELRRLFLVED
Sbjct: 738 RVFTAVLQAMRKTEDGHPFRQYLERDVLLSADAVHTHSEALLRRINTALVELRRLFLVED 797
Query: 457 LVDSLKFGVLLWCLTYVGACFNGITLIILXLDSA 558
LVDSLK V LW LTYVG+ FNG+TL+I+ L A
Sbjct: 798 LVDSLKLAVGLWLLTYVGSWFNGLTLLIIALIGA 831
>UniRef50_UPI0000E4A8E3 Cluster: PREDICTED: similar to reticulon 4
isoform B2; n=3; Strongylocentrotus purpuratus|Rep:
PREDICTED: similar to reticulon 4 isoform B2 -
Strongylocentrotus purpuratus
Length = 943
Score = 91.1 bits (216), Expect = 4e-17
Identities = 48/90 (53%), Positives = 57/90 (63%)
Frame = +1
Query: 274 FRLYKNVLQAVQKTNDGHPFKWLLEAEVSVSXXXXXXXXXXXXXXXXXXXYELRRLFLVE 453
FR+YK VL AVQK+++G PFK LE +V++S LR L LVE
Sbjct: 805 FRVYKTVLAAVQKSDEGSPFKPYLEIDVTLSEDQIESYSKKAVQKINVCITSLRHLLLVE 864
Query: 454 DLVDSLKFGVLLWCLTYVGACFNGITLIIL 543
DLVDS+KF V LW LTYVGA FNG+TLIIL
Sbjct: 865 DLVDSIKFAVGLWLLTYVGAWFNGLTLIIL 894
>UniRef50_A7SZV0 Cluster: Predicted protein; n=1; Nematostella
vectensis|Rep: Predicted protein - Nematostella
vectensis
Length = 177
Score = 78.2 bits (184), Expect = 3e-13
Identities = 39/89 (43%), Positives = 54/89 (60%)
Frame = +1
Query: 274 FRLYKNVLQAVQKTNDGHPFKWLLEAEVSVSXXXXXXXXXXXXXXXXXXXYELRRLFLVE 453
+R+ V+ A+QK+ +PFK LL+ E+ + LRRLFLVE
Sbjct: 52 YRVGMTVMGAIQKSGTENPFKTLLDKEIEIPKEKAVEMAESLAEHINCLTKSLRRLFLVE 111
Query: 454 DLVDSLKFGVLLWCLTYVGACFNGITLII 540
D+VDS+KFGV+LW L+YVGA F+ +TLII
Sbjct: 112 DIVDSIKFGVMLWVLSYVGAWFSMLTLII 140
>UniRef50_Q7RTJ4 Cluster: RTN-B2; n=11; Ciona intestinalis|Rep:
RTN-B2 - Ciona intestinalis (Transparent sea squirt)
Length = 377
Score = 76.6 bits (180), Expect = 8e-13
Identities = 40/95 (42%), Positives = 55/95 (57%)
Frame = +1
Query: 274 FRLYKNVLQAVQKTNDGHPFKWLLEAEVSVSXXXXXXXXXXXXXXXXXXXYELRRLFLVE 453
FRLYK VLQ + T +PF+ LL+ EV++S R L LV+
Sbjct: 239 FRLYKLVLQTLNGTQQPNPFQSLLDMEVTLSKDQIHKYADVILDHLNCTLVCTRDLVLVK 298
Query: 454 DLVDSLKFGVLLWCLTYVGACFNGITLIILXLDSA 558
++V SLKF V +W LTY+G CFNG+TL+IL + +A
Sbjct: 299 NMVASLKFAVFMWLLTYIGCCFNGLTLLILGVIAA 333
>UniRef50_O75298 Cluster: Reticulon-2; n=8; Mammalia|Rep:
Reticulon-2 - Homo sapiens (Human)
Length = 545
Score = 72.9 bits (171), Expect = 1e-11
Identities = 36/89 (40%), Positives = 54/89 (60%)
Frame = +1
Query: 277 RLYKNVLQAVQKTNDGHPFKWLLEAEVSVSXXXXXXXXXXXXXXXXXXXYELRRLFLVED 456
R+Y+ VLQAV + + +PF+ L+ +++++ +LR FLVED
Sbjct: 395 RVYRKVLQAVHRGDGANPFQAYLDVDLTLTREQTERLSHQITSRVVSAATQLRHFFLVED 454
Query: 457 LVDSLKFGVLLWCLTYVGACFNGITLIIL 543
LVDSLK +L + LT+VGA FNG+TL+IL
Sbjct: 455 LVDSLKLALLFYILTFVGAIFNGLTLLIL 483
Score = 35.1 bits (77), Expect = 2.5
Identities = 15/40 (37%), Positives = 25/40 (62%)
Frame = +2
Query: 551 IALFTLXKAYEMNKAQVDANLELAXAKINXITAKVRAAVP 670
I LFT+ Y ++AQ+D + L +++ I AK+RA +P
Sbjct: 486 IGLFTIPLLYRQHQAQIDQYVGLVTNQLSHIKAKIRAKIP 525
>UniRef50_O70622 Cluster: Reticulon-2; n=20; Eutheria|Rep:
Reticulon-2 - Mus musculus (Mouse)
Length = 471
Score = 72.5 bits (170), Expect = 1e-11
Identities = 48/174 (27%), Positives = 75/174 (43%)
Frame = +1
Query: 22 SLLVEFLKXLTQSPWHARVQTPRFTSQADLPPRGPVESLIYWRNXXXXXXXXXXXXXXXX 201
+++ E + L Q P A+ S+ L P V L+YW++
Sbjct: 237 NVVEEHWRLLEQEPITAQCLDSTDQSEFMLEPLLLVADLLYWKDTRTSGAVFTGLMASLL 296
Query: 202 XXXXXXXXXXXXXXXXXXXXXXXXFRLYKNVLQAVQKTNDGHPFKWLLEAEVSVSXXXXX 381
R+Y+ VLQAV + + +PF+ L+ +++++
Sbjct: 297 CLLHFSIVSVAAHLALLGLCATISLRVYRKVLQAVHRGDGTNPFQAYLDMDLTLTREQTE 356
Query: 382 XXXXXXXXXXXXXXYELRRLFLVEDLVDSLKFGVLLWCLTYVGACFNGITLIIL 543
+LR FLVEDLVDSLK +L + LT+VGA FNG+TL+IL
Sbjct: 357 RLSQQIASHVVSTATQLRHFFLVEDLVDSLKLALLFYILTFVGAIFNGLTLVIL 410
Score = 35.9 bits (79), Expect = 1.4
Identities = 15/40 (37%), Positives = 26/40 (65%)
Frame = +2
Query: 551 IALFTLXKAYEMNKAQVDANLELAXAKINXITAKVRAAVP 670
+ALFT+ Y ++AQ+D + L +++ I AK+RA +P
Sbjct: 413 VALFTVPLLYRQHQAQIDQYVGLVTNQLSHIKAKIRAKIP 452
>UniRef50_Q4FZ76 Cluster: RTN2-A; n=7; Xenopus|Rep: RTN2-A - Xenopus
laevis (African clawed frog)
Length = 321
Score = 70.9 bits (166), Expect = 4e-11
Identities = 36/94 (38%), Positives = 56/94 (59%)
Frame = +1
Query: 277 RLYKNVLQAVQKTNDGHPFKWLLEAEVSVSXXXXXXXXXXXXXXXXXXXYELRRLFLVED 456
RLY +L A+++ N +PF++ L+ ++ ++ LR LFLVE+
Sbjct: 184 RLYTKLLHALKRGNGANPFQYYLDTDLKLTTKQAEEIVARAFSLASTTLCTLRSLFLVEE 243
Query: 457 LVDSLKFGVLLWCLTYVGACFNGITLIILXLDSA 558
L DSLKF V+++ LTYVGA FNGIT+++L + A
Sbjct: 244 LKDSLKFLVIVYLLTYVGAVFNGITVLLLCVIGA 277
>UniRef50_Q4TTE6 Cluster: Reticulon; n=7; Caenorhabditis|Rep:
Reticulon - Caenorhabditis remanei
Length = 222
Score = 60.9 bits (141), Expect = 4e-08
Identities = 29/92 (31%), Positives = 50/92 (54%)
Frame = +1
Query: 274 FRLYKNVLQAVQKTNDGHPFKWLLEAEVSVSXXXXXXXXXXXXXXXXXXXYELRRLFLVE 453
FR YK + ++KT+ +PF +L ++++ +L++L VE
Sbjct: 76 FRAYKKIEAQIKKTDTENPFNEILAKDLALPQEKVHAQADVITEHATCVANKLKKLIFVE 135
Query: 454 DLVDSLKFGVLLWCLTYVGACFNGITLIILXL 549
++S+KFG++LW LTYV + F+G TL +L L
Sbjct: 136 SPLESIKFGLILWSLTYVASWFSGCTLAVLAL 167
>UniRef50_UPI000155BB4D Cluster: PREDICTED: similar to RTN2 protein,
partial; n=1; Ornithorhynchus anatinus|Rep: PREDICTED:
similar to RTN2 protein, partial - Ornithorhynchus
anatinus
Length = 188
Score = 58.0 bits (134), Expect = 3e-07
Identities = 27/42 (64%), Positives = 34/42 (80%)
Frame = +1
Query: 430 LRRLFLVEDLVDSLKFGVLLWCLTYVGACFNGITLIILXLDS 555
LR LFLVED+VDSLK +L + LT+VGA FNG+TL+IL + S
Sbjct: 107 LRHLFLVEDIVDSLKLALLFYILTFVGAVFNGLTLLILGVIS 148
>UniRef50_Q4G5T7 Cluster: Reticulon 8-c; n=6; Clupeocephala|Rep:
Reticulon 8-c - Danio rerio (Zebrafish) (Brachydanio
rerio)
Length = 208
Score = 54.8 bits (126), Expect = 3e-06
Identities = 31/88 (35%), Positives = 49/88 (55%), Gaps = 1/88 (1%)
Frame = +1
Query: 280 LYKNVLQAVQKTNDG-HPFKWLLEAEVSVSXXXXXXXXXXXXXXXXXXXYELRRLFLVED 456
LYK + V + NDG HPF+ L+ + +++ EL+RLF ++
Sbjct: 57 LYKAM--TVTRLNDGSHPFQSYLDEDHTLTDEDTVRMAEQMVLLIATAVSELKRLFFIDS 114
Query: 457 LVDSLKFGVLLWCLTYVGACFNGITLII 540
++DS+KF V L+ LTYVG NG+TL++
Sbjct: 115 IMDSVKFIVFLYLLTYVGVQANGLTLVM 142
>UniRef50_A7SJN6 Cluster: Predicted protein; n=1; Nematostella
vectensis|Rep: Predicted protein - Nematostella
vectensis
Length = 208
Score = 53.6 bits (123), Expect = 7e-06
Identities = 31/89 (34%), Positives = 42/89 (47%)
Frame = +1
Query: 277 RLYKNVLQAVQKTNDGHPFKWLLEAEVSVSXXXXXXXXXXXXXXXXXXXYELRRLFLVED 456
RL A KT HP L +++VS +RRLFLVED
Sbjct: 54 RLLFTARSAFMKTEFQHPLNSYLSKDINVSKDRADLIGERAAGYIVDSTVSVRRLFLVED 113
Query: 457 LVDSLKFGVLLWCLTYVGACFNGITLIIL 543
L DS+K V+L+ L+Y+ F+GITL +
Sbjct: 114 LADSIKLLVVLYILSYLAQWFSGITLTFI 142
Score = 35.1 bits (77), Expect = 2.5
Identities = 14/41 (34%), Positives = 26/41 (63%)
Frame = +2
Query: 551 IALFTLXKAYEMNKAQVDANLELAXAKINXITAKVRAAVPL 673
I LFT+ KAY+M + ++++ + ++ + K+ AAVPL
Sbjct: 145 IGLFTVPKAYDMYREEINSAMSTIKVAVDDLLDKINAAVPL 185
>UniRef50_Q4G5K8 Cluster: Reticulon 2c; n=6; Clupeocephala|Rep:
Reticulon 2c - Danio rerio (Zebrafish) (Brachydanio
rerio)
Length = 203
Score = 52.0 bits (119), Expect = 2e-05
Identities = 28/89 (31%), Positives = 46/89 (51%)
Frame = +1
Query: 277 RLYKNVLQAVQKTNDGHPFKWLLEAEVSVSXXXXXXXXXXXXXXXXXXXYELRRLFLVED 456
R+Y +L +Q + HPF+ L+ ++S+S LR L V +
Sbjct: 55 RIYYKLLHVLQLGDGVHPFQSYLDLDISLSGEEAEHCLQRAIVLSCSALETLRNLIFVGN 114
Query: 457 LVDSLKFGVLLWCLTYVGACFNGITLIIL 543
L SLKF +L++ +T++G NG+TLII+
Sbjct: 115 LFSSLKFWLLMYVVTFLGNLCNGLTLIII 143
>UniRef50_Q5DE04 Cluster: SJCHGC02814 protein; n=1; Schistosoma
japonicum|Rep: SJCHGC02814 protein - Schistosoma
japonicum (Blood fluke)
Length = 214
Score = 44.8 bits (101), Expect = 0.003
Identities = 21/37 (56%), Positives = 27/37 (72%)
Frame = +1
Query: 433 RRLFLVEDLVDSLKFGVLLWCLTYVGACFNGITLIIL 543
R +FL+ D S+KF VLL+ LTY+GA FN +TL IL
Sbjct: 121 REIFLLTDPAASIKFAVLLYLLTYIGAQFNFLTLCIL 157
>UniRef50_Q24199 Cluster: Tropomyosin-like protein; n=2; Drosophila
melanogaster|Rep: Tropomyosin-like protein - Drosophila
melanogaster (Fruit fly)
Length = 158
Score = 40.7 bits (91), Expect = 0.050
Identities = 20/37 (54%), Positives = 25/37 (67%)
Frame = +1
Query: 439 LFLVEDLVDSLKFGVLLWCLTYVGACFNGITLIILXL 549
L LVE DSLKF VLL + +G CFNG+TL+I +
Sbjct: 112 LLLVEKWEDSLKFLVLLCGINLLGDCFNGLTLLIFGM 148
>UniRef50_UPI0000E822BE Cluster: PREDICTED: similar to RTN3w; n=1;
Gallus gallus|Rep: PREDICTED: similar to RTN3w - Gallus
gallus
Length = 115
Score = 38.7 bits (86), Expect = 0.20
Identities = 14/21 (66%), Positives = 20/21 (95%)
Frame = +1
Query: 274 FRLYKNVLQAVQKTNDGHPFK 336
FR+YK+V+QAVQK+ +GHPF+
Sbjct: 95 FRVYKSVIQAVQKSEEGHPFR 115
>UniRef50_Q5DDK2 Cluster: SJCHGC06495 protein; n=1; Schistosoma
japonicum|Rep: SJCHGC06495 protein - Schistosoma
japonicum (Blood fluke)
Length = 165
Score = 37.1 bits (82), Expect = 0.62
Identities = 27/92 (29%), Positives = 44/92 (47%), Gaps = 5/92 (5%)
Frame = +1
Query: 277 RLYKNVL---QAVQKTNDG--HPFKWLLEAEVSVSXXXXXXXXXXXXXXXXXXXYELRRL 441
+LY VL +A Q+T++ H F LE ++ S +LRR+
Sbjct: 22 KLYNVVLGSNKAEQETSNSSKHSFHSWLEYDILFSEDKIAQRAAAASEHLSEKLNQLRRI 81
Query: 442 FLVEDLVDSLKFGVLLWCLTYVGACFNGITLI 537
L+ D ++ K + L+ L+ VG+ FN +TLI
Sbjct: 82 LLMHDYFETAKLAICLYLLSIVGSWFNLLTLI 113
>UniRef50_Q55HN1 Cluster: Putative uncharacterized protein; n=3;
Filobasidiella neoformans|Rep: Putative uncharacterized
protein - Cryptococcus neoformans (Filobasidiella
neoformans)
Length = 2272
Score = 34.3 bits (75), Expect = 4.4
Identities = 14/31 (45%), Positives = 18/31 (58%)
Frame = -2
Query: 144 VDQRLHWSTGRQVCLGSESRRLHSSVPWRLS 52
V QR+ W TG+ LG + H VPWR+S
Sbjct: 566 VAQRMKWETGQFSVLGEDETEEHHFVPWRVS 596
Database: uniref50
Posted date: Oct 5, 2007 11:19 AM
Number of letters in database: 575,637,011
Number of sequences in database: 1,657,284
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 389,668,352
Number of Sequences: 1657284
Number of extensions: 4463139
Number of successful extensions: 19047
Number of sequences better than 10.0: 35
Number of HSP's better than 10.0 without gapping: 18285
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 18989
length of database: 575,637,011
effective HSP length: 100
effective length of database: 409,908,611
effective search space used: 82801539422
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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