Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= MFBP02_F_J24
(900 letters)
Database: uniref50
1,657,284 sequences; 575,637,011 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
UniRef50_Q7NWA9 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=7... 195 1e-48
UniRef50_UPI0000D56743 Cluster: PREDICTED: similar to 3-hydroxyi... 189 1e-46
UniRef50_Q54CX6 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=3... 188 2e-46
UniRef50_P28811 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=7... 176 5e-43
UniRef50_P31937 Cluster: 3-hydroxyisobutyrate dehydrogenase, mit... 173 5e-42
UniRef50_Q399N0 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=7... 170 5e-41
UniRef50_A7UBP6 Cluster: Putative 3-hydroxyisobutyrate dehydroge... 169 1e-40
UniRef50_A7JGH8 Cluster: Predicted protein; n=1; Francisella tul... 165 1e-39
UniRef50_A1QPH6 Cluster: 3-hydroxyisobutyrate dehydrogenase mmsB... 159 1e-37
UniRef50_P63936 Cluster: Probable 3-hydroxyisobutyrate dehydroge... 159 1e-37
UniRef50_Q9V8M5 Cluster: Probable 3-hydroxyisobutyrate dehydroge... 157 4e-37
UniRef50_A0QSJ0 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=3... 154 3e-36
UniRef50_Q0K0E2 Cluster: 3-Hydroxyisobutyrate dehydrogenase; n=1... 153 6e-36
UniRef50_Q22B54 Cluster: 3-hydroxyisobutyrate dehydrogenase fami... 153 6e-36
UniRef50_Q83D20 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=9... 152 1e-35
UniRef50_Q55702 Cluster: Uncharacterized oxidoreductase slr0229;... 150 4e-35
UniRef50_A0JUJ6 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=2... 150 5e-35
UniRef50_A0UF54 Cluster: 6-phosphogluconate dehydrogenase, NAD-b... 146 9e-34
UniRef50_A3I4V2 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=1... 144 2e-33
UniRef50_Q0QLF5 Cluster: 2-hydroxymethyl glutarate dehydrogenase... 144 3e-33
UniRef50_A6NVP0 Cluster: Putative uncharacterized protein; n=1; ... 144 3e-33
UniRef50_Q4FMJ3 Cluster: 6-phosphogluconate dehydrogenase; n=2; ... 143 5e-33
UniRef50_Q1AVA4 Cluster: 2-hydroxy-3-oxopropionate reductase; n=... 143 6e-33
UniRef50_Q9SUC0 Cluster: Probable 3-hydroxyisobutyrate dehydroge... 142 8e-33
UniRef50_Q9A8J9 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=2... 141 2e-32
UniRef50_Q8KL12 Cluster: Probable 6-phosphogluconate dehydrogena... 141 2e-32
UniRef50_Q4ZQL5 Cluster: 3-hydroxyisobutyrate dehydrogenase prec... 141 3e-32
UniRef50_Q9K9L1 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=2... 140 3e-32
UniRef50_A1SIN3 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=1... 140 4e-32
UniRef50_Q67QX0 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=1... 138 2e-31
UniRef50_O34948 Cluster: Uncharacterized oxidoreductase ykwC; n=... 138 2e-31
UniRef50_Q1V2R0 Cluster: MmsB-like protein; n=2; Candidatus Pela... 134 2e-30
UniRef50_A2SP40 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=1... 134 2e-30
UniRef50_A0GVR3 Cluster: 6-phosphogluconate dehydrogenase, NAD-b... 133 5e-30
UniRef50_Q41DK0 Cluster: 6-phosphogluconate dehydrogenase, NAD-b... 133 7e-30
UniRef50_A5V0D4 Cluster: 6-phosphogluconate dehydrogenase, NAD-b... 133 7e-30
UniRef50_Q1QWU9 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=1... 132 1e-29
UniRef50_Q8ES28 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=1... 130 4e-29
UniRef50_Q58PL4 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=1... 130 4e-29
UniRef50_Q0SBQ9 Cluster: 2-hydroxy-3-oxopropionate reductase; n=... 130 4e-29
UniRef50_A4IN46 Cluster: 3-hydroxyisobutyrate dehydrogenase-like... 130 4e-29
UniRef50_A0C2T7 Cluster: Chromosome undetermined scaffold_145, w... 130 4e-29
UniRef50_Q97XZ7 Cluster: Oxidoreductase; n=6; Thermoprotei|Rep: ... 130 5e-29
UniRef50_Q11FC5 Cluster: 6-phosphogluconate dehydrogenase, NAD-b... 128 2e-28
UniRef50_A3RRS1 Cluster: 2-hydroxy-3-oxopropionate reductase; n=... 128 2e-28
UniRef50_Q92D17 Cluster: Lin1004 protein; n=10; Bacilli|Rep: Lin... 126 6e-28
UniRef50_A3SJ77 Cluster: Probable oxidoreductase; n=1; Roseovari... 125 1e-27
UniRef50_Q89UN2 Cluster: Bll1384 protein; n=9; Bacteria|Rep: Bll... 125 2e-27
UniRef50_A6SW62 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=1... 124 2e-27
UniRef50_Q183P5 Cluster: 2-hydroxy-3-oxopropionate reductase; n=... 123 7e-27
UniRef50_Q930C6 Cluster: Probable; n=8; Alphaproteobacteria|Rep:... 122 1e-26
UniRef50_A6LT11 Cluster: 6-phosphogluconate dehydrogenase, NAD-b... 122 1e-26
UniRef50_P0ABQ3 Cluster: 2-hydroxy-3-oxopropionate reductase; n=... 122 1e-26
UniRef50_Q18X68 Cluster: 6-phosphogluconate dehydrogenase, NAD-b... 122 2e-26
UniRef50_Q12CU4 Cluster: 2-hydroxy-3-oxopropionate reductase; n=... 122 2e-26
UniRef50_A6GTB5 Cluster: 6-phosphogluconate dehydrogenase, NAD-b... 121 2e-26
UniRef50_A3K497 Cluster: Probable 6-phosphogluconate dehydrogena... 121 2e-26
UniRef50_Q01ZG6 Cluster: 2-hydroxy-3-oxopropionate reductase; n=... 121 3e-26
UniRef50_Q1GJB9 Cluster: 6-phosphogluconate dehydrogenase NAD-bi... 120 4e-26
UniRef50_A0G5G5 Cluster: 6-phosphogluconate dehydrogenase, NAD-b... 120 7e-26
UniRef50_A0N0V2 Cluster: BtdhL; n=1; Azoarcus anaerobius|Rep: Bt... 119 9e-26
UniRef50_A6P2M7 Cluster: Putative uncharacterized protein; n=2; ... 119 1e-25
UniRef50_Q1QWQ5 Cluster: 6-phosphogluconate dehydrogenase, NAD-b... 118 2e-25
UniRef50_A2U9T6 Cluster: 6-phosphogluconate dehydrogenase, NAD-b... 118 2e-25
UniRef50_Q5L168 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=1... 118 2e-25
UniRef50_Q03UI4 Cluster: 3-hydroxyisobutyrate dehydrogenase rela... 117 4e-25
UniRef50_Q01QM2 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=1... 117 5e-25
UniRef50_A0LMG6 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=9... 117 5e-25
UniRef50_Q2JEV5 Cluster: 6-phosphogluconate dehydrogenase, NAD-b... 116 6e-25
UniRef50_Q0S5S3 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=1... 116 6e-25
UniRef50_Q89R44 Cluster: Oxidoreductase; n=23; Bacteria|Rep: Oxi... 116 1e-24
UniRef50_Q5WBB8 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=1... 116 1e-24
UniRef50_Q4PCH4 Cluster: Putative uncharacterized protein; n=1; ... 115 1e-24
UniRef50_Q4Q7T9 Cluster: 2-hydroxy-3-oxopropionate reductase, pu... 114 3e-24
UniRef50_A1B741 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=3... 113 4e-24
UniRef50_Q84VC8 Cluster: Gamma hydroxybutyrate dehydrogenase-lik... 113 4e-24
UniRef50_A5USN9 Cluster: 6-phosphogluconate dehydrogenase, NAD-b... 113 6e-24
UniRef50_Q94B07 Cluster: Gamma hydroxybutyrate dehydrogenase; n=... 113 6e-24
UniRef50_Q4KH51 Cluster: 3-hydroxyisobutyrate dehydrogenase fami... 112 1e-23
UniRef50_Q2UHA9 Cluster: Predicted dehydrogenase; n=16; Pezizomy... 112 1e-23
UniRef50_Q0LNZ7 Cluster: 3-hydroxyisobutyrate dehydrogenase prec... 111 2e-23
UniRef50_A1WM48 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=1... 111 2e-23
UniRef50_Q0URA2 Cluster: Putative uncharacterized protein; n=1; ... 111 2e-23
UniRef50_Q0F1Y7 Cluster: 6-phosphogluconate dehydrogenase, NAD-b... 111 2e-23
UniRef50_A5P0V0 Cluster: 6-phosphogluconate dehydrogenase, NAD-b... 111 2e-23
UniRef50_Q6C351 Cluster: Yarrowia lipolytica chromosome F of str... 111 2e-23
UniRef50_Q7WCG3 Cluster: Putative uncharacterized protein; n=2; ... 111 3e-23
UniRef50_Q39MY1 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=2... 111 3e-23
UniRef50_Q13PY3 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=2... 110 4e-23
UniRef50_A0K0Z6 Cluster: 6-phosphogluconate dehydrogenase, NAD-b... 110 4e-23
UniRef50_A0FZ96 Cluster: 6-phosphogluconate dehydrogenase, NAD-b... 110 4e-23
UniRef50_Q84H84 Cluster: Putative oxidoreductase; n=1; Arthrobac... 110 5e-23
UniRef50_A3H5R1 Cluster: 6-phosphogluconate dehydrogenase, NAD-b... 109 9e-23
UniRef50_A3VLN6 Cluster: Oxidoreductase; n=1; Rhodobacterales ba... 109 1e-22
UniRef50_A0LTQ8 Cluster: 6-phosphogluconate dehydrogenase, NAD-b... 109 1e-22
UniRef50_Q7WG50 Cluster: Probable oxidoreductase; n=1; Bordetell... 108 2e-22
UniRef50_Q3DYV4 Cluster: NADP oxidoreductase, coenzyme F420-depe... 107 3e-22
UniRef50_A5GPC0 Cluster: Hydroxyacid dehydrogenase/reductase fam... 107 3e-22
UniRef50_A0G5F9 Cluster: 6-phosphogluconate dehydrogenase, NAD-b... 107 3e-22
UniRef50_Q89HA0 Cluster: Oxidoreductase; n=1; Bradyrhizobium jap... 107 4e-22
UniRef50_Q1YHQ4 Cluster: Putative 2-hydroxy-3-oxopropionate redu... 107 4e-22
UniRef50_Q13LQ9 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=1... 107 4e-22
UniRef50_A5VEA3 Cluster: 2-hydroxy-3-oxopropionate reductase; n=... 107 4e-22
UniRef50_Q8TT25 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=2... 107 4e-22
UniRef50_A5FTT0 Cluster: 6-phosphogluconate dehydrogenase, NAD-b... 107 5e-22
UniRef50_A1UP64 Cluster: 6-phosphogluconate dehydrogenase, NAD-b... 106 9e-22
UniRef50_Q0UVR9 Cluster: Putative uncharacterized protein; n=1; ... 105 1e-21
UniRef50_UPI00015B4162 Cluster: PREDICTED: similar to MGC108315 ... 104 3e-21
UniRef50_A6SUL3 Cluster: 2-hydroxy-3-oxopropionate reductase; n=... 104 3e-21
UniRef50_A3WAC4 Cluster: Dehydrogenase; n=4; Bacteria|Rep: Dehyd... 104 4e-21
UniRef50_Q8VYC5 Cluster: Fructose-bisphosphate aldolase; n=12; c... 104 4e-21
UniRef50_A1ZWM5 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=1... 103 5e-21
UniRef50_Q656T5 Cluster: Oxidoreductase-like; n=3; Oryza sativa|... 103 5e-21
UniRef50_Q606G9 Cluster: Oxidoreductase, Gfo/Idh/MocA family; n=... 103 6e-21
UniRef50_Q121N3 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=1... 103 6e-21
UniRef50_A7IE35 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=2... 103 6e-21
UniRef50_Q9L7S0 Cluster: Uncharacterized oxidoreductase yihU; n=... 103 6e-21
UniRef50_A3JU55 Cluster: Predicted dehydrogenase, with NAD(P)-bi... 102 1e-20
UniRef50_A5VBF0 Cluster: 2-hydroxy-3-oxopropionate reductase pre... 102 1e-20
UniRef50_A3X9R7 Cluster: 3-hydroxyisobutyrate dehydrogenase fami... 102 1e-20
UniRef50_A7PEG7 Cluster: Chromosome chr11 scaffold_13, whole gen... 102 1e-20
UniRef50_A0JXR2 Cluster: 2-hydroxy-3-oxopropionate reductase; n=... 101 2e-20
UniRef50_Q8UBW3 Cluster: Oxidoredutase; n=1; Agrobacterium tumef... 101 3e-20
UniRef50_Q1IQE6 Cluster: 2-hydroxy-3-oxopropionate reductase pre... 101 3e-20
UniRef50_A7DSF1 Cluster: 2-hydroxy-3-oxopropionate reductase; n=... 101 3e-20
UniRef50_Q0RCX7 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=1... 100 4e-20
UniRef50_A1R2J4 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=1... 100 4e-20
UniRef50_Q47AR2 Cluster: NADP oxidoreductase, coenzyme F420-depe... 99 8e-20
UniRef50_Q39FA8 Cluster: 2-hydroxy-3-oxopropionate reductase; n=... 99 8e-20
UniRef50_Q1N6I0 Cluster: Putative oxidoreductase protein; n=1; O... 99 8e-20
UniRef50_A1WJN2 Cluster: 6-phosphogluconate dehydrogenase, NAD-b... 99 8e-20
UniRef50_Q8PK98 Cluster: 3-hydroxyisobutirate dehydrogenase; n=3... 100 1e-19
UniRef50_A1UJF2 Cluster: 6-phosphogluconate dehydrogenase, NAD-b... 100 1e-19
UniRef50_A3WMG5 Cluster: Probable 3-hydroxyisobutyrate dehydroge... 99 2e-19
UniRef50_Q830A7 Cluster: 2-hydroxy-3-oxopropionate reductase; n=... 98 2e-19
UniRef50_Q0FFH2 Cluster: Putative 2-hydroxyacid dehydrogenase; n... 98 2e-19
UniRef50_A6EH53 Cluster: Putative uncharacterized protein; n=1; ... 98 2e-19
UniRef50_Q49A26 Cluster: Cytokine-like nuclear factor n-pac; n=4... 98 2e-19
UniRef50_Q73P00 Cluster: 3-hydroxyacid dehydrogenase family prot... 97 5e-19
UniRef50_A0R1N4 Cluster: 6-phosphogluconate dehydrogenase, NAD-b... 97 7e-19
UniRef50_A0QUD5 Cluster: 3-hydroxyisobutyrate dehydrogenase fami... 97 7e-19
UniRef50_A0NRG5 Cluster: 6-phosphogluconate dehydrogenase, NAD-b... 97 7e-19
UniRef50_Q4WV01 Cluster: Oxidoreductase, acting on the CH-OH gro... 97 7e-19
UniRef50_A0LDJ3 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=1... 96 9e-19
UniRef50_O33730 Cluster: Uncharacterized oxidoreductase Sfri_150... 96 9e-19
UniRef50_Q8EW87 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=1... 95 2e-18
UniRef50_Q89RT2 Cluster: Bll2680 protein; n=1; Bradyrhizobium ja... 95 2e-18
UniRef50_Q9LM23 Cluster: Fructose-bisphosphate aldolase; n=2; Ar... 95 2e-18
UniRef50_Q7WNK6 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=1... 95 2e-18
UniRef50_A6VYD9 Cluster: 2-hydroxy-3-oxopropionate reductase pre... 95 3e-18
UniRef50_Q46TQ0 Cluster: UDP-glucose/GDP-mannose dehydrogenase:P... 94 4e-18
UniRef50_Q2BFK1 Cluster: Oxidoreductase; n=1; Bacillus sp. NRRL ... 94 4e-18
UniRef50_Q1B326 Cluster: 6-phosphogluconate dehydrogenase, NAD-b... 94 4e-18
UniRef50_Q7NR40 Cluster: Probable 3-hydroxyisobutyrate dehydroge... 94 5e-18
UniRef50_Q6UCZ9 Cluster: Predicted oxidoreductase; n=2; environm... 94 5e-18
UniRef50_Q3W9W7 Cluster: 6-phosphogluconate dehydrogenase, NAD b... 94 5e-18
UniRef50_A4SWE8 Cluster: 2-hydroxy-3-oxopropionate reductase pre... 93 9e-18
UniRef50_Q9JYH6 Cluster: 3-hydroxyacid dehydrogenase; n=5; Prote... 93 1e-17
UniRef50_A1CAY2 Cluster: Oxidoreductase, acting on the CH-OH gro... 93 1e-17
UniRef50_Q89M84 Cluster: Blr4309 protein; n=6; Bradyrhizobiaceae... 92 2e-17
UniRef50_O66454 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=3... 91 3e-17
UniRef50_P77161 Cluster: 2-hydroxy-3-oxopropionate reductase; n=... 91 3e-17
UniRef50_Q20XN2 Cluster: 6-phosphogluconate dehydrogenase, NAD-b... 91 4e-17
UniRef50_Q0KC92 Cluster: 3-Hydroxyisobutyrate dehydrogenase; n=1... 91 4e-17
UniRef50_Q019Z7 Cluster: Oxidoreductase-like; n=1; Ostreococcus ... 91 4e-17
UniRef50_Q9LNP0 Cluster: F1L3.35; n=8; Magnoliophyta|Rep: F1L3.3... 91 5e-17
UniRef50_Q98I20 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=2... 90 6e-17
UniRef50_Q7VYY0 Cluster: Putative oxidoreductase; n=4; Bordetell... 90 6e-17
UniRef50_Q5LQR0 Cluster: 6-phosphogluconate dehydrogenase domain... 90 6e-17
UniRef50_Q5FQ06 Cluster: Putative oxidoreductase; n=1; Gluconoba... 90 6e-17
UniRef50_Q3W3N3 Cluster: Putative uncharacterized protein; n=1; ... 90 6e-17
UniRef50_Q2CHC8 Cluster: Oxidoreductase; n=1; Oceanicola granulo... 90 8e-17
UniRef50_A0GPK7 Cluster: 6-phosphogluconate dehydrogenase, NAD-b... 89 1e-16
UniRef50_A6VLT0 Cluster: 2-hydroxy-3-oxopropionate reductase; n=... 89 1e-16
UniRef50_A6F020 Cluster: Putative uncharacterized protein; n=1; ... 89 1e-16
UniRef50_Q3W9L4 Cluster: Putative uncharacterized protein; n=1; ... 89 2e-16
UniRef50_A6G049 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=1... 89 2e-16
UniRef50_Q12H32 Cluster: 6-phosphogluconate dehydrogenase, NAD-b... 88 2e-16
UniRef50_A2C1U6 Cluster: 3-hydroxyisobutyrate dehydrogenase and ... 87 6e-16
UniRef50_Q0C8I2 Cluster: Predicted protein; n=3; Pezizomycotina|... 86 1e-15
UniRef50_Q1EPJ1 Cluster: 6-phosphogluconate dehydrogenase NAD-bi... 85 2e-15
UniRef50_Q74D68 Cluster: 3-hydroxyisobutyrate dehydrogenase fami... 85 3e-15
UniRef50_Q1GF31 Cluster: 6-phosphogluconate dehydrogenase NAD-bi... 85 3e-15
UniRef50_UPI0001597301 Cluster: YfjR; n=1; Bacillus amyloliquefa... 84 5e-15
UniRef50_Q9HLR4 Cluster: Putative uncharacterized protein Ta0161... 84 5e-15
UniRef50_A3EW86 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=1... 83 9e-15
UniRef50_A7H7Z5 Cluster: 6-phosphogluconate dehydrogenase NAD-bi... 83 1e-14
UniRef50_A6RMW8 Cluster: Putative uncharacterized protein; n=2; ... 83 1e-14
UniRef50_A7DWL2 Cluster: Putative dehydrogenase; n=1; Streptomyc... 82 2e-14
UniRef50_A5WG80 Cluster: 6-phosphogluconate dehydrogenase, NAD-b... 82 2e-14
UniRef50_A3Y8R5 Cluster: Putative dehydrogenase; n=1; Marinomona... 82 2e-14
UniRef50_Q7Q161 Cluster: ENSANGP00000013149; n=11; Culicidae|Rep... 82 2e-14
UniRef50_A3LTC4 Cluster: 3-hydroxyisobutyrate dehydrogenase-like... 82 2e-14
UniRef50_Q5LNV6 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=2... 81 4e-14
UniRef50_Q3WJ00 Cluster: 6-phosphogluconate dehydrogenase, NAD b... 81 4e-14
UniRef50_A7RG59 Cluster: Predicted protein; n=1; Nematostella ve... 81 5e-14
UniRef50_P71825 Cluster: Uncharacterized oxidoreductase Rv0770/M... 81 5e-14
UniRef50_A0JRK4 Cluster: 6-phosphogluconate dehydrogenase, NAD-b... 80 7e-14
UniRef50_A0R1N5 Cluster: 6-phosphogluconate dehydrogenase, NAD-b... 80 9e-14
UniRef50_Q55JR1 Cluster: Putative uncharacterized protein; n=2; ... 80 9e-14
UniRef50_Q9RX16 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=6... 79 1e-13
UniRef50_Q8F4I7 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=4... 79 1e-13
UniRef50_A0YMN9 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=3... 79 1e-13
UniRef50_Q98K09 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=7... 79 2e-13
UniRef50_A1UJF3 Cluster: 6-phosphogluconate dehydrogenase, NAD-b... 79 2e-13
UniRef50_A0RU56 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=1... 79 2e-13
UniRef50_Q0BTJ3 Cluster: 2-hydroxy-3-oxopropionate reductase; n=... 78 3e-13
UniRef50_A1GFG2 Cluster: 6-phosphogluconate dehydrogenase, NAD-b... 78 3e-13
UniRef50_Q97ZE5 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=4... 78 4e-13
UniRef50_Q6F842 Cluster: Putative 3-hydroxyisobutyrate dehydroge... 77 5e-13
UniRef50_A5P600 Cluster: 6-phosphogluconate dehydrogenase, NAD-b... 77 5e-13
UniRef50_A4ECY9 Cluster: Putative uncharacterized protein; n=1; ... 77 8e-13
UniRef50_A1SQ87 Cluster: 6-phosphogluconate dehydrogenase, NAD-b... 77 8e-13
UniRef50_Q4WXG9 Cluster: 3-hydroxyisobutyrate dehydrogenase, put... 77 8e-13
UniRef50_Q4Q9Z1 Cluster: Dehydrogenase-like protein; n=6; Trypan... 76 1e-12
UniRef50_Q6RXW5 Cluster: Succinic semialdehyde dehydrogenase; n=... 75 2e-12
UniRef50_Q21ZN3 Cluster: 6-phosphogluconate dehydrogenase, NAD-b... 75 2e-12
UniRef50_A3Q3U7 Cluster: 6-phosphogluconate dehydrogenase, NAD-b... 75 2e-12
UniRef50_UPI0000E49FD0 Cluster: PREDICTED: similar to gamma hydr... 75 3e-12
UniRef50_Q120Q9 Cluster: 6-phosphogluconate dehydrogenase, NAD-b... 75 3e-12
UniRef50_Q0RIL5 Cluster: Putative uncharacterized protein; n=1; ... 75 3e-12
UniRef50_A0GI22 Cluster: 6-phosphogluconate dehydrogenase, NAD-b... 75 3e-12
UniRef50_A0AWL7 Cluster: 6-phosphogluconate dehydrogenase, NAD-b... 75 3e-12
UniRef50_Q392H4 Cluster: 6-phosphogluconate dehydrogenase, NAD-b... 74 4e-12
UniRef50_Q221W9 Cluster: 2-hydroxy-3-oxopropionate reductase; n=... 74 4e-12
UniRef50_Q7NEW9 Cluster: Glr3759 protein; n=3; Bacteria|Rep: Glr... 74 6e-12
UniRef50_A3ES45 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=1... 74 6e-12
UniRef50_Q9I1R8 Cluster: Probable dehydrogenase; n=7; Pseudomona... 73 8e-12
UniRef50_Q21ZT0 Cluster: 6-phosphogluconate dehydrogenase, NAD-b... 73 8e-12
UniRef50_Q033P2 Cluster: 3-hydroxyisobutyrate dehydrogenase rela... 73 8e-12
UniRef50_A6R0U9 Cluster: Predicted protein; n=1; Ajellomyces cap... 73 1e-11
UniRef50_Q2JEN4 Cluster: 6-phosphogluconate dehydrogenase, NAD-b... 73 1e-11
UniRef50_Q39KK8 Cluster: 6-phosphogluconate dehydrogenase, NAD-b... 72 2e-11
UniRef50_A3H9B3 Cluster: 6-phosphogluconate dehydrogenase, NAD-b... 72 2e-11
UniRef50_A3ET09 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=3... 72 2e-11
UniRef50_Q8U2W2 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=1... 72 2e-11
UniRef50_Q21AH6 Cluster: 6-phosphogluconate dehydrogenase, NAD-b... 71 5e-11
UniRef50_Q55W03 Cluster: Putative uncharacterized protein; n=2; ... 71 5e-11
UniRef50_Q3W031 Cluster: Putative dehydrogenase; n=1; Frankia sp... 70 9e-11
UniRef50_A1UDJ6 Cluster: 6-phosphogluconate dehydrogenase, NAD-b... 69 1e-10
UniRef50_Q1V2K7 Cluster: NADP oxidoreductase, coenzyme F420-depe... 69 2e-10
UniRef50_A5CN67 Cluster: Putative beta-hydroxyacid dehydrogenase... 69 2e-10
UniRef50_A4FKN9 Cluster: 2-hydroxy-3-oxopropionate reductase; n=... 69 2e-10
UniRef50_A0VSV4 Cluster: 6-phosphogluconate dehydrogenase, NAD-b... 69 2e-10
UniRef50_A7I8V1 Cluster: 6-phosphogluconate dehydrogenase, NAD-b... 69 2e-10
UniRef50_A0K107 Cluster: 2-hydroxy-3-oxopropionate reductase; n=... 68 3e-10
UniRef50_Q13VQ8 Cluster: Putative dehydrogenase/oxidoreductase p... 68 4e-10
UniRef50_UPI0000D55E08 Cluster: PREDICTED: similar to CG4747-PA;... 67 5e-10
UniRef50_Q5GUM4 Cluster: Dehydrogenase; n=5; Gammaproteobacteria... 66 9e-10
UniRef50_Q01PV6 Cluster: 6-phosphogluconate dehydrogenase, NAD-b... 66 9e-10
UniRef50_Q1GM24 Cluster: 6-phosphogluconate dehydrogenase NAD-bi... 66 1e-09
UniRef50_Q82ZC2 Cluster: 6-phosphogluconate dehydrogenase family... 65 3e-09
UniRef50_Q89GM2 Cluster: Bll6323 protein; n=6; Proteobacteria|Re... 64 4e-09
UniRef50_Q1INE9 Cluster: 6-phosphogluconate dehydrogenase, NAD-b... 64 6e-09
UniRef50_Q8YRT5 Cluster: 3-hydroxyacid dehydrogenase; n=5; Cyano... 62 2e-08
UniRef50_A5FVG0 Cluster: 6-phosphogluconate dehydrogenase, NAD-b... 62 2e-08
UniRef50_A1WEB7 Cluster: 6-phosphogluconate dehydrogenase, NAD-b... 62 2e-08
UniRef50_Q0W2D7 Cluster: Putative 6-phosphogluconate dehydrogena... 61 3e-08
UniRef50_A0QZR7 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=1... 60 6e-08
UniRef50_Q0SAG5 Cluster: Phosphogluconate dehydrogenase; n=23; A... 60 8e-08
UniRef50_A3H6C3 Cluster: 6-phosphogluconate dehydrogenase, NAD-b... 60 8e-08
UniRef50_A3PRM1 Cluster: 6-phosphogluconate dehydrogenase, NAD-b... 59 1e-07
UniRef50_Q6D9X4 Cluster: Putative 2-hydroxy-3-oxopropionate redu... 59 2e-07
UniRef50_Q9RBX6 Cluster: IgiB; n=1; Vogesella indigofera|Rep: Ig... 58 2e-07
UniRef50_A4EEN1 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=1... 58 2e-07
UniRef50_Q5FU44 Cluster: Putative oxidoreductase; n=1; Gluconoba... 58 3e-07
UniRef50_Q0RMX6 Cluster: Putative reductase; n=1; Frankia alni A... 57 5e-07
UniRef50_Q9RU02 Cluster: 6-phosphogluconate dehydrogenase; n=24;... 57 7e-07
UniRef50_Q19TN0 Cluster: 3-hydroxyisobutyrate dehydrogenase fami... 57 7e-07
UniRef50_O66788 Cluster: 6-phosphogluconate dehydrogenase; n=2; ... 56 9e-07
UniRef50_Q1NHF5 Cluster: Putative oxidoreductase; n=1; Sphingomo... 56 1e-06
UniRef50_A4S5A4 Cluster: Predicted protein; n=2; Ostreococcus|Re... 56 1e-06
UniRef50_Q1NHG5 Cluster: Putative uncharacterized protein; n=1; ... 56 2e-06
UniRef50_A3PSD9 Cluster: 6-phosphogluconate dehydrogenase, decar... 55 2e-06
UniRef50_Q6KZX0 Cluster: 2-hydroxy-3-oxopropionate reductase; n=... 55 2e-06
UniRef50_Q92P61 Cluster: 6-phosphogluconate dehydrogenase, decar... 55 3e-06
UniRef50_Q9K9H3 Cluster: 6-phosphogluconate dehydrogenase; n=7; ... 54 4e-06
UniRef50_Q3J9H5 Cluster: 6-phosphogluconate dehydrogenase, decar... 54 7e-06
UniRef50_O34969 Cluster: Uncharacterized oxidoreductase yfjR; n=... 54 7e-06
UniRef50_Q220G7 Cluster: 6-phosphogluconate dehydrogenase, NAD-b... 53 9e-06
UniRef50_Q4WSB8 Cluster: 6-phosphogluconate dehydrogenase family... 53 1e-05
UniRef50_A1RWA6 Cluster: 6-phosphogluconate dehydrogenase, NAD-b... 53 1e-05
UniRef50_P80859 Cluster: 6-phosphogluconate dehydrogenase, decar... 52 2e-05
UniRef50_UPI0000EBE4FC Cluster: PREDICTED: hypothetical protein;... 52 2e-05
UniRef50_A4BV63 Cluster: 3-hydroxyacid dehydrogenase; n=1; Nitro... 52 3e-05
UniRef50_Q0QWD5 Cluster: Putative 3-hydroxyisobutyrate dehydroge... 52 3e-05
UniRef50_Q5FHQ8 Cluster: 6-phosphogluconate dehydrogenase, decar... 50 6e-05
UniRef50_A6ELE2 Cluster: 6-phosphogluconate dehydrogenase, decar... 50 6e-05
UniRef50_A7CWR7 Cluster: 6-phosphogluconate dehydrogenase NAD-bi... 50 8e-05
UniRef50_A4JSC3 Cluster: 6-phosphogluconate dehydrogenase, NAD-b... 50 8e-05
UniRef50_Q9V8M5-2 Cluster: Isoform C of Q9V8M5 ; n=1; Drosophila... 50 1e-04
UniRef50_Q0U6Q6 Cluster: Putative uncharacterized protein; n=5; ... 50 1e-04
UniRef50_P54448 Cluster: Uncharacterized protein yqeC; n=13; Bac... 50 1e-04
UniRef50_P37754 Cluster: 6-phosphogluconate dehydrogenase, decar... 50 1e-04
UniRef50_A0FZ97 Cluster: 6-phosphogluconate dehydrogenase, NAD-b... 49 2e-04
UniRef50_Q0V6D4 Cluster: Putative uncharacterized protein; n=1; ... 49 2e-04
UniRef50_A2BJA4 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=1... 49 2e-04
UniRef50_Q5MZU3 Cluster: 3-hydroxyacid dehydrogenase; n=3; Cyano... 48 3e-04
UniRef50_A6T947 Cluster: Putative dehydrogenase; n=1; Klebsiella... 48 3e-04
UniRef50_Q660W3 Cluster: 6-phosphogluconate dehydrogenase, decar... 48 4e-04
UniRef50_Q64V77 Cluster: 6-phosphogluconate dehydrogenase, decar... 48 4e-04
UniRef50_Q629W3 Cluster: 2-hydroxy-3-oxopropionate reductase; n=... 47 6e-04
UniRef50_Q2UET7 Cluster: Predicted protein; n=7; Eurotiomycetida... 47 8e-04
UniRef50_Q836Q9 Cluster: 6-phosphogluconate dehydrogenase, decar... 46 0.001
UniRef50_A0PKN6 Cluster: 6-phosphogluconate dehydrogenase, decar... 46 0.001
UniRef50_Q17761 Cluster: 6-phosphogluconate dehydrogenase, decar... 46 0.001
UniRef50_A5GJY3 Cluster: 3-hydroxyisobutyrate dehydrogenase rela... 44 0.004
UniRef50_Q53WI1 Cluster: Putative uncharacterized protein TTHB24... 44 0.005
UniRef50_Q8TUC1 Cluster: Predicted protein; n=4; Methanosarcinac... 44 0.005
UniRef50_Q9F3P6 Cluster: Putative dehydrogenase; n=1; Streptomyc... 43 0.009
UniRef50_P21577 Cluster: 6-phosphogluconate dehydrogenase, decar... 43 0.009
UniRef50_P31072 Cluster: 6-phosphogluconate dehydrogenase, decar... 43 0.012
UniRef50_Q9CDN4 Cluster: 6-phosphogluconate dehydrogenase; n=12;... 42 0.016
UniRef50_Q7TZG1 Cluster: 6-phosphogluconate dehydrogenase, decar... 42 0.028
UniRef50_Q1AZK2 Cluster: 6-phosphogluconate dehydrogenase, NAD-b... 42 0.028
UniRef50_O32911 Cluster: 6-phosphogluconate dehydrogenase, decar... 42 0.028
UniRef50_Q9YE14 Cluster: Putative dehydrogenase; n=1; Aeropyrum ... 42 0.028
UniRef50_A5K3L2 Cluster: 6-phosphogluconate dehydrogenase, decar... 40 0.065
UniRef50_A0Y665 Cluster: 6-phosphogluconate dehydrogenase; n=3; ... 40 0.086
UniRef50_A2Q7E9 Cluster: Function: mmsB of P. aeruginosa is invo... 40 0.086
UniRef50_Q11JE9 Cluster: 6-phosphogluconate dehydrogenase, NAD-b... 40 0.11
UniRef50_A1FPN2 Cluster: 6-phosphogluconate dehydrogenase, NAD-b... 39 0.15
UniRef50_A4ENK2 Cluster: 3-demethylubiquinone-9 3-methyltransfer... 39 0.20
UniRef50_Q5B0A2 Cluster: Putative uncharacterized protein; n=1; ... 38 0.26
UniRef50_Q9YFQ6 Cluster: L-lysine 6-dehydrogenase; n=1; Aeropyru... 38 0.35
UniRef50_Q2LGT9 Cluster: 6-phosphogluconate dehydrogenase; n=6; ... 38 0.35
UniRef50_Q8SRX1 Cluster: 6-PHOSPHOGLUCONATE DEHYDROGENASE; n=1; ... 38 0.46
UniRef50_A6RYG0 Cluster: Putative uncharacterized protein; n=1; ... 38 0.46
UniRef50_P41572 Cluster: 6-phosphogluconate dehydrogenase, decar... 37 0.81
UniRef50_Q988C8 Cluster: 3-hydroxybutyryl-coA dehydrogenase; n=1... 36 1.1
UniRef50_Q8EW86 Cluster: HAD superfamily hydrolase; n=1; Mycopla... 36 1.1
UniRef50_Q6N3Q8 Cluster: 6-phosphogluconate dehydrogenase; n=57;... 36 1.1
UniRef50_Q1YFU0 Cluster: Posibble methylase involved in ubiquino... 36 1.1
UniRef50_A6W129 Cluster: 6-phosphogluconate dehydrogenase, decar... 36 1.4
UniRef50_A4ES45 Cluster: Methyltransferase type 11; n=1; Roseoba... 36 1.4
UniRef50_A4ARS6 Cluster: 6-phosphogluconate dehydrogenase, NAD-b... 36 1.4
UniRef50_Q944B6 Cluster: Arogenate dehydrogenase 1, chloroplast ... 36 1.4
UniRef50_Q5PAV2 Cluster: 3-demethylubiquinone-9 3-methyltransfer... 35 2.5
UniRef50_Q39LP6 Cluster: 6-phosphogluconate dehydrogenase, NAD-b... 35 2.5
UniRef50_Q1N6E5 Cluster: Erythronate-4-phosphate dehydrogenase; ... 35 2.5
UniRef50_A6VZU5 Cluster: D-isomer specific 2-hydroxyacid dehydro... 35 2.5
UniRef50_A4SGI3 Cluster: NAD-dependent epimerase/dehydratase; n=... 35 2.5
UniRef50_A1U1I8 Cluster: Erythronate-4-phosphate dehydrogenase; ... 35 2.5
UniRef50_UPI0000E46E06 Cluster: PREDICTED: similar to MGC107852 ... 35 3.3
UniRef50_Q2S7E0 Cluster: Phosphoglycerate dehydrogenase and rela... 35 3.3
UniRef50_A4XCN7 Cluster: Methyltransferase type 11; n=2; Salinis... 35 3.3
UniRef50_A3Y0Y8 Cluster: Putative tartronate semialdehyde reduct... 35 3.3
UniRef50_A3U721 Cluster: Putative uncharacterized protein; n=1; ... 35 3.3
UniRef50_UPI0000E221EA Cluster: PREDICTED: similar to NMDAR1 sub... 34 4.3
UniRef50_UPI000050FDFD Cluster: COG0569: K+ transport systems, N... 34 4.3
UniRef50_Q7WCB1 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=4... 34 4.3
UniRef50_Q3DWX0 Cluster: 6-phosphogluconate dehydrogenase, NAD-b... 34 5.7
UniRef50_A6G079 Cluster: Leucine dehydrogenase; n=1; Plesiocysti... 34 5.7
UniRef50_UPI0000E8153F Cluster: PREDICTED: hypothetical protein;... 33 7.5
UniRef50_Q0S6F7 Cluster: 3-demethylubiquinone-9 3-O-methyltransf... 33 7.5
UniRef50_Q0HQ96 Cluster: CHAP domain containing protein precurso... 33 7.5
UniRef50_A0Z3U5 Cluster: Putative uncharacterized protein; n=1; ... 33 7.5
UniRef50_A7QQA4 Cluster: Chromosome undetermined scaffold_141, w... 33 7.5
UniRef50_Q5KFL3 Cluster: Putative uncharacterized protein; n=2; ... 33 7.5
UniRef50_Q0VQC3 Cluster: Erythronate-4-phosphate dehydrogenase; ... 33 7.5
UniRef50_Q88ZU6 Cluster: Phosphoglycerate dehydrogenase; n=2; La... 33 9.9
UniRef50_Q6F272 Cluster: 1-pyrroline-5-carboxylate reductase; n=... 33 9.9
UniRef50_O67636 Cluster: Prephenate dehydrogenase; n=1; Aquifex ... 33 9.9
UniRef50_Q9RQV3 Cluster: Putative prephenate dehydrogenase TyrC;... 33 9.9
UniRef50_Q2BJD5 Cluster: Probable UDP-glucose/GDP-mannose dehydr... 33 9.9
UniRef50_A6TCR4 Cluster: 2-ketoacid reductase; n=1; Klebsiella p... 33 9.9
UniRef50_A6NX21 Cluster: Putative uncharacterized protein; n=1; ... 33 9.9
UniRef50_A0Q3X1 Cluster: Putative uncharacterized protein; n=1; ... 33 9.9
UniRef50_A0GGU8 Cluster: Putative uncharacterized protein; n=1; ... 33 9.9
>UniRef50_Q7NWA9 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=7;
Proteobacteria|Rep: 3-hydroxyisobutyrate dehydrogenase -
Chromobacterium violaceum
Length = 296
Score = 195 bits (476), Expect = 1e-48
Identities = 99/215 (46%), Positives = 131/215 (60%)
Frame = +3
Query: 180 KNVAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGVTPANSIXXXXXXXXXX 359
+N+AF+GLGNMGG MA NL+ KGF V +D S DAL A G A+S
Sbjct: 2 ENIAFIGLGNMGGPMAVNLLNKGFKVSAFDLSADALAKVAAAGGRAASSAADAAESASVV 61
Query: 360 XSILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAPV 539
S+L + K V +YLG +G+ A KG+L+ID STID +++ A EKGL DAPV
Sbjct: 62 ISMLPAGKHVAGLYLGDNGLFARLPKGALVIDCSTIDAGTARKVAEGAREKGLSMLDAPV 121
Query: 540 SGGVMGAQNATLAFMAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMGIT 719
SGG GA TL F+ GG ED + P+L+ MG FH G G+GQ AK+ NNML+GI
Sbjct: 122 SGGTAGAAAGTLTFIVGGAAEDLAHARPVLEAMGKNIFHAGGAGAGQTAKICNNMLLGIL 181
Query: 720 GMAXAECMXMGIKMGLXPKVLLDVLNNSSXRSWST 824
AE + +G+K GL PKVL ++++ SS R+W+T
Sbjct: 182 MAGTAEALALGVKNGLDPKVLSEIISKSSGRNWAT 216
>UniRef50_UPI0000D56743 Cluster: PREDICTED: similar to
3-hydroxyisobutyrate dehydrogenase; n=1; Tribolium
castaneum|Rep: PREDICTED: similar to
3-hydroxyisobutyrate dehydrogenase - Tribolium castaneum
Length = 315
Score = 189 bits (460), Expect = 1e-46
Identities = 97/213 (45%), Positives = 129/213 (60%)
Frame = +3
Query: 186 VAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGVTPANSIXXXXXXXXXXXS 365
+AF+G+GNMG MA NLVKKG TVR +D + NA + G N+ +
Sbjct: 26 LAFIGIGNMGSRMANNLVKKGETVRVFDLTP--ANAKSVPGAQVCNNQEEAVKDASVIIT 83
Query: 366 ILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAPVSG 545
+L + +V D LG +G++ HA KGSLLID STI P V +++ G F DAPVSG
Sbjct: 84 MLPNGDIVKDTVLGTNGILKHASKGSLLIDCSTIQPQVAQEVSKATYSAGFKFLDAPVSG 143
Query: 546 GVMGAQNATLAFMAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMGITGM 725
GV GA+ TL FM GG K+ + P+L MGA HCG G+GQ+AKL NN+++ IT +
Sbjct: 144 GVTGAEAGTLTFMVGGDKQVLNSADPILMKMGANVLHCGDSGAGQIAKLCNNLILAITMI 203
Query: 726 AXAECMXMGIKMGLXPKVLLDVLNNSSXRSWST 824
E M +GIKMGL PK L ++N S+ RSWS+
Sbjct: 204 GTCEGMNLGIKMGLDPKTLASIINVSTGRSWSS 236
>UniRef50_Q54CX6 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=3;
cellular organisms|Rep: 3-hydroxyisobutyrate
dehydrogenase - Dictyostelium discoideum AX4
Length = 321
Score = 188 bits (457), Expect = 2e-46
Identities = 91/223 (40%), Positives = 135/223 (60%)
Frame = +3
Query: 156 RAYSSNTDKNVAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGVTPANSIXX 335
R S+++ K V F+GLGNMGG A NL+KKG + +D SKD +N + G ANS
Sbjct: 15 RYMSTSSSKTVGFIGLGNMGGHQAINLIKKGHNLIVFDMSKDNMNRLKEKGAKIANSPAE 74
Query: 336 XXXXXXXXXSILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKG 515
++L ++ V +VY G++G+ + G+LL+DSSTIDP +++ IA +
Sbjct: 75 VAKEADVIVTMLPASAHVKNVYCGENGIFQTVRPGTLLLDSSTIDPATAREVASIAKKHQ 134
Query: 516 LGFTDAPVSGGVMGAQNATLAFMAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLT 695
D PVSGG GA+ TL FM GG ++DF + L+ MG HCG +G+GQVAK+
Sbjct: 135 STMLDCPVSGGTGGAEAGTLTFMVGGSEQDFNTAKTYLECMGKNIVHCGDVGTGQVAKVC 194
Query: 696 NNMLMGITGMAXAECMXMGIKMGLXPKVLLDVLNNSSXRSWST 824
NN+++GI+ +A +E M +G+K G+ PK L + N SS R W++
Sbjct: 195 NNLVLGISMIAVSEAMNLGVKQGMDPKKLAGIFNTSSARCWTS 237
>UniRef50_P28811 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=72;
Proteobacteria|Rep: 3-hydroxyisobutyrate dehydrogenase -
Pseudomonas aeruginosa
Length = 298
Score = 176 bits (429), Expect = 5e-43
Identities = 94/213 (44%), Positives = 126/213 (59%)
Frame = +3
Query: 183 NVAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGVTPANSIXXXXXXXXXXX 362
++AFLGLGNMGG MAANL+K G V +D A+ + G A+S
Sbjct: 3 DIAFLGLGNMGGPMAANLLKAGHRVNVFDLQPKAVLGLVEQGAQGADSALQCCEGAEVVI 62
Query: 363 SILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAPVS 542
S+L + + V +YLG DG++A LLID STI P +++ A KGL DAPVS
Sbjct: 63 SMLPAGQHVESLYLGDDGLLARVAGKPLLIDCSTIAPETARKVAEAAAAKGLTLLDAPVS 122
Query: 543 GGVMGAQNATLAFMAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMGITG 722
GGV GA+ TL+F+ GG E F R+ P+L+ MG FH G G+GQVAK+ NNML+GI
Sbjct: 123 GGVGGARAGTLSFIVGGPAEGFARARPVLENMGRNIFHAGDHGAGQVAKICNNMLLGILM 182
Query: 723 MAXAECMXMGIKMGLXPKVLLDVLNNSSXRSWS 821
AE + +G+K GL P VL +V+ SS +W+
Sbjct: 183 AGTAEALALGVKNGLDPAVLSEVMKQSSGGNWA 215
>UniRef50_P31937 Cluster: 3-hydroxyisobutyrate dehydrogenase,
mitochondrial precursor; n=38; Eumetazoa|Rep:
3-hydroxyisobutyrate dehydrogenase, mitochondrial
precursor - Homo sapiens (Human)
Length = 336
Score = 173 bits (421), Expect = 5e-42
Identities = 93/223 (41%), Positives = 132/223 (59%)
Frame = +3
Query: 156 RAYSSNTDKNVAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGVTPANSIXX 335
R+ +S T V F+GLGNMG MA NL+K G+ + YD DA G +S
Sbjct: 34 RSVASKTP--VGFIGLGNMGNPMAKNLMKHGYPLIIYDVFPDACKEFQDAGEQVVSSPAD 91
Query: 336 XXXXXXXXXSILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKG 515
++L ++ ++ Y G +G++ KKGSLLIDSSTIDP V K++ + G
Sbjct: 92 VAEKADRIITMLPTSINAIEAYSGANGILKKVKKGSLLIDSSTIDPAVSKELAKEVEKMG 151
Query: 516 LGFTDAPVSGGVMGAQNATLAFMAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLT 695
F DAPVSGGV A++ L FM GG +++F + LL MG+ +CG +G+GQ AK+
Sbjct: 152 AVFMDAPVSGGVGAARSGNLTFMVGGVEDEFAAAQELLGCMGSNVVYCGAVGTGQAAKIC 211
Query: 696 NNMLMGITGMAXAECMXMGIKMGLXPKVLLDVLNNSSXRSWST 824
NNML+ I+ + AE M +GI++GL PK+L +LN SS R WS+
Sbjct: 212 NNMLLAISMIGTAEAMNLGIRLGLDPKLLAKILNMSSGRCWSS 254
>UniRef50_Q399N0 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=72;
cellular organisms|Rep: 3-hydroxyisobutyrate
dehydrogenase - Burkholderia sp. (strain 383)
(Burkholderia cepacia (strain ATCC 17760/ NCIB 9086 /
R18194))
Length = 299
Score = 170 bits (413), Expect = 5e-41
Identities = 91/213 (42%), Positives = 121/213 (56%)
Frame = +3
Query: 186 VAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGVTPANSIXXXXXXXXXXXS 365
+ F+GLG+MG MA NL+K G V +D S DAL A G A S +
Sbjct: 3 IGFIGLGHMGAPMALNLLKAGHEVHAFDLSADALRALQDAGAQVAASPRDAASGATFVIT 62
Query: 366 ILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAPVSG 545
+L + V V G++GV+A G+ +IDSSTIDP + + E G F DAPVSG
Sbjct: 63 MLPAAPHVRSVLSGENGVLAGLGAGATVIDSSTIDPASAQAFGALVREHGGAFVDAPVSG 122
Query: 546 GVMGAQNATLAFMAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMGITGM 725
G GA TL FM GG DFER P+L MG HCG G GQVAK+ NN+++GI+
Sbjct: 123 GTGGAAAGTLTFMVGGSDADFERVKPVLAGMGKNIVHCGATGMGQVAKVCNNLVLGISMA 182
Query: 726 AXAECMXMGIKMGLXPKVLLDVLNNSSXRSWST 824
A +E M +G+ +G+ PKVL ++N S+ R WS+
Sbjct: 183 AVSEAMSLGVALGIDPKVLAGIVNTSTGRCWSS 215
>UniRef50_A7UBP6 Cluster: Putative 3-hydroxyisobutyrate
dehydrogenase; n=1; Paracoccus methylutens|Rep: Putative
3-hydroxyisobutyrate dehydrogenase - Paracoccus
methylutens
Length = 302
Score = 169 bits (410), Expect = 1e-40
Identities = 86/202 (42%), Positives = 122/202 (60%)
Frame = +3
Query: 186 VAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGVTPANSIXXXXXXXXXXXS 365
V FLGLG MG MA NL G V YDPS++ AAK G+ A+ + +
Sbjct: 4 VGFLGLGRMGFPMARNLATAGHDVHVYDPSEEVGRKAAKAGLKTASRVDVAVEGADFVIT 63
Query: 366 ILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAPVSG 545
++ + + VL+++LG DGV+A KGS+ IDSSTID +++ E+G+ DAPVSG
Sbjct: 64 MVPTGRHVLEIFLGDDGVLAKMAKGSMAIDSSTIDTADARRLHAAGRERGIAVLDAPVSG 123
Query: 546 GVMGAQNATLAFMAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMGITGM 725
GVMGA+ TL FM GG ED ER+ P+L+ MG + FH G+ G GQ AKL NN+L GI+ +
Sbjct: 124 GVMGAEAGTLTFMVGGSAEDLERARPVLEAMGRRIFHAGEPGVGQAAKLCNNLLAGISMI 183
Query: 726 AXAECMXMGIKMGLXPKVLLDV 791
A +E + +GL + + ++
Sbjct: 184 AVSEAFALARHLGLDARKMQEI 205
>UniRef50_A7JGH8 Cluster: Predicted protein; n=1; Francisella
tularensis subsp. novicida GA99-3549|Rep: Predicted
protein - Francisella tularensis subsp. novicida
GA99-3549
Length = 293
Score = 165 bits (402), Expect = 1e-39
Identities = 91/214 (42%), Positives = 117/214 (54%)
Frame = +3
Query: 180 KNVAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGVTPANSIXXXXXXXXXX 359
KN+AF+GLG MG MA NL+ G+ V G+D S D LN NG A SI
Sbjct: 2 KNIAFIGLGCMGLHMAKNLIDNGYKVYGFDMSLDQLNKHQNNGGIAAKSIKEACGYADAI 61
Query: 360 XSILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAPV 539
L V +V DG++ AK G+++ID+STID N + A + L DAPV
Sbjct: 62 ILSLPGPNQVSNVCDSSDGILKIAKAGTIIIDTSTIDANTSVLLAKKAKQNNLHMLDAPV 121
Query: 540 SGGVMGAQNATLAFMAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMGIT 719
SGG++GAQNATL FM GG KE FER L MG K H G G G + KL NNML+GI
Sbjct: 122 SGGIIGAQNATLTFMVGGDKEIFERCKNLFNSMGKKYLHVGDNGKGLIIKLINNMLLGIN 181
Query: 720 GMAXAECMXMGIKMGLXPKVLLDVLNNSSXRSWS 821
+A +E K G+ K D++ +S+ SW+
Sbjct: 182 MIAASEACNFAEKTGINLKTFYDIVASSTGSSWA 215
>UniRef50_A1QPH6 Cluster: 3-hydroxyisobutyrate dehydrogenase mmsB;
n=5; Mycobacterium|Rep: 3-hydroxyisobutyrate
dehydrogenase mmsB - Mycobacterium tuberculosis (strain
F11)
Length = 315
Score = 159 bits (385), Expect = 1e-37
Identities = 86/212 (40%), Positives = 121/212 (57%)
Frame = +3
Query: 186 VAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGVTPANSIXXXXXXXXXXXS 365
+AFLGLGNMG M+ANLV G VRG+DP+ A + AA +GV S +
Sbjct: 4 IAFLGLGNMGAPMSANLVGAGHVVRGFDPAPTAASGAAAHGVAVFRSAPEAVAEADVVIT 63
Query: 366 ILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAPVSG 545
+L + +VV Y V+A A+ +L IDSSTI +++ +A G+ DAPVSG
Sbjct: 64 MLPTGEVVRRCYTD---VLAAARPATLFIDSSTISVTDAREVHALAESHGMLQLDAPVSG 120
Query: 546 GVMGAQNATLAFMAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMGITGM 725
GV GA ATLAFM GG + R+ P+L+ M K HCG G+GQ AK+ NNM++ + +
Sbjct: 121 GVKGAAAATLAFMVGGDESTLRRARPVLEPMAGKIIHCGAAGAGQAAKVCNNMVLAVQQI 180
Query: 726 AXAECMXMGIKMGLXPKVLLDVLNNSSXRSWS 821
A AE + K+GL + L DV+ ++ W+
Sbjct: 181 AIAEAFVLAEKLGLSAQSLFDVITGATGNCWA 212
>UniRef50_P63936 Cluster: Probable 3-hydroxyisobutyrate
dehydrogenase; n=25; Bacteria|Rep: Probable
3-hydroxyisobutyrate dehydrogenase - Mycobacterium bovis
Length = 294
Score = 159 bits (385), Expect = 1e-37
Identities = 86/212 (40%), Positives = 121/212 (57%)
Frame = +3
Query: 186 VAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGVTPANSIXXXXXXXXXXXS 365
+AFLGLGNMG M+ANLV G VRG+DP+ A + AA +GV S +
Sbjct: 4 IAFLGLGNMGAPMSANLVGAGHVVRGFDPAPTAASGAAAHGVAVFRSAPEAVAEADVVIT 63
Query: 366 ILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAPVSG 545
+L + +VV Y V+A A+ +L IDSSTI +++ +A G+ DAPVSG
Sbjct: 64 MLPTGEVVRRCYTD---VLAAARPATLFIDSSTISVTDAREVHALAESHGMLQLDAPVSG 120
Query: 546 GVMGAQNATLAFMAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMGITGM 725
GV GA ATLAFM GG + R+ P+L+ M K HCG G+GQ AK+ NNM++ + +
Sbjct: 121 GVKGAAAATLAFMVGGDESTLRRARPVLEPMAGKIIHCGAAGAGQAAKVCNNMVLAVQQI 180
Query: 726 AXAECMXMGIKMGLXPKVLLDVLNNSSXRSWS 821
A AE + K+GL + L DV+ ++ W+
Sbjct: 181 AIAEAFVLAEKLGLSAQSLFDVITGATGNCWA 212
>UniRef50_Q9V8M5 Cluster: Probable 3-hydroxyisobutyrate
dehydrogenase, mitochondrial precursor; n=4;
Diptera|Rep: Probable 3-hydroxyisobutyrate
dehydrogenase, mitochondrial precursor - Drosophila
melanogaster (Fruit fly)
Length = 324
Score = 157 bits (381), Expect = 4e-37
Identities = 86/229 (37%), Positives = 125/229 (54%), Gaps = 2/229 (0%)
Frame = +3
Query: 144 TAARRAYSSNTDKNVAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGVTPAN 323
T R + KN+ F+GLGNMG MA+NL+K G + +D SK A + A G T
Sbjct: 17 TLVRAMSTQGGAKNIGFVGLGNMGANMASNLIKAGHKLHVFDISKPACDGLAAKGATVYA 76
Query: 324 SIXXXXXXXXXXXSILTSNKVVLDVY--LGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFP 497
++L +N +V Y + DGV K ++ IDSSTI P++ K +
Sbjct: 77 KTSELAKNSDFVITMLPNNAIVDASYDEMTADGV----NKDTIFIDSSTISPDLVKSLQK 132
Query: 498 IALEKGLGFTDAPVSGGVMGAQNATLAFMAGGRKEDFERSLPLLKVMGAKQFHCGQIGSG 677
KG F DAPVSGGV GA+ ATL FM GG + ++ +L+ MG K HCG G G
Sbjct: 133 KISAKGARFIDAPVSGGVPGAEQATLTFMVGGTEAEYNAVKAVLECMGKKITHCGVYGMG 192
Query: 678 QVAKLTNNMLMGITGMAXAECMXMGIKMGLXPKVLLDVLNNSSXRSWST 824
Q AKL NNM++ I+ + +E M + ++ GL V +++N+S+ R W++
Sbjct: 193 QAAKLCNNMMLAISMIGVSEAMNLAVRQGLDANVFAEIINSSTGRCWAS 241
>UniRef50_A0QSJ0 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=3;
Bacteria|Rep: 3-hydroxyisobutyrate dehydrogenase -
Mycobacterium smegmatis (strain ATCC 700084 / mc(2)155)
Length = 290
Score = 154 bits (373), Expect = 3e-36
Identities = 86/212 (40%), Positives = 115/212 (54%)
Frame = +3
Query: 186 VAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGVTPANSIXXXXXXXXXXXS 365
+AFLGLG+MGG MAANL G TVRG+DP + AA G+ + +
Sbjct: 4 IAFLGLGHMGGPMAANLAAAGHTVRGFDPMPASREAAEAKGIKVFGTGAEAASEAEVVIT 63
Query: 366 ILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAPVSG 545
L + +V Y V+ A G+L ID+STI + + + ALEKG DAPVSG
Sbjct: 64 SLPNGDIVKSCYAE---VLPAAPTGTLFIDTSTISVDDARTVHTQALEKGHAQLDAPVSG 120
Query: 546 GVMGAQNATLAFMAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMGITGM 725
GV GA TLAFM GG + ER+ P+L M K HCG G+GQ AKL NNM++ + +
Sbjct: 121 GVKGATAGTLAFMVGGEDDAVERARPILDPMAGKIIHCGGSGTGQAAKLCNNMVLAVQQI 180
Query: 726 AXAECMXMGIKMGLXPKVLLDVLNNSSXRSWS 821
A E + K+GL + L DV+ ++ WS
Sbjct: 181 AIGEAFVLAEKLGLSAQSLFDVITGATGNCWS 212
>UniRef50_Q0K0E2 Cluster: 3-Hydroxyisobutyrate dehydrogenase; n=1;
Ralstonia eutropha H16|Rep: 3-Hydroxyisobutyrate
dehydrogenase - Ralstonia eutropha (strain ATCC 17699 /
H16 / DSM 428 / Stanier 337)(Cupriavidus necator (strain
ATCC 17699 / H16 / DSM 428 / Stanier337))
Length = 299
Score = 153 bits (371), Expect = 6e-36
Identities = 79/212 (37%), Positives = 122/212 (57%)
Frame = +3
Query: 186 VAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGVTPANSIXXXXXXXXXXXS 365
+AF+GLGNMG MA NLV+ G V+G+D S+ AL A G S+ S
Sbjct: 4 IAFIGLGNMGMPMALNLVRAGHDVQGFDISEAALAGFAGQGGQSQRSVAAAVDGASIVIS 63
Query: 366 ILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAPVSG 545
I+ + V ++Y GV+ A G+LLI+SSTI P + + A + G DAPV+G
Sbjct: 64 IVRNADDVKNLYCTAGGVLDVAAPGALLIESSTIGPAAARAVAAEAAQAGFAMLDAPVAG 123
Query: 546 GVMGAQNATLAFMAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMGITGM 725
G GA+ A L FM GG + F+R+ P+L+ MGA+ F+ G G+GQ+AKL NN++ ++
Sbjct: 124 GQAGAREARLTFMVGGARTAFDRAEPVLRQMGARIFYAGASGNGQIAKLCNNLIACVSSA 183
Query: 726 AXAECMXMGIKMGLXPKVLLDVLNNSSXRSWS 821
+E +G K+G+ + + D++ S+ + W+
Sbjct: 184 VVSEAFILGSKLGMDYQTMYDIITQSTGQCWT 215
>UniRef50_Q22B54 Cluster: 3-hydroxyisobutyrate dehydrogenase family
protein; n=1; Tetrahymena thermophila SB210|Rep:
3-hydroxyisobutyrate dehydrogenase family protein -
Tetrahymena thermophila SB210
Length = 316
Score = 153 bits (371), Expect = 6e-36
Identities = 86/217 (39%), Positives = 124/217 (57%), Gaps = 2/217 (0%)
Frame = +3
Query: 180 KNVAFLGLGNMGGFMAANLVKKG-FTVRGYDPSKDALNAAAKNGVTPANSIXXXXXXXXX 356
+ V F+GLGNMGG MA NL +KG F V +D +KD+L AK G+ +
Sbjct: 17 ETVGFIGLGNMGGPMALNLARKGGFEVIAFDVNKDSLKKYAKEGLAVCEDVTVLARKANK 76
Query: 357 XXSILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAP 536
++L ++ V V G++G+ + K SL IDSSTI + +I+ A + + DAP
Sbjct: 77 FVTMLPNSSHVSSVLEGENGLFQKSAKNSLFIDSSTISYHAAIKIYENAKKVNQRYIDAP 136
Query: 537 VSGGVMGAQNATLAFMAGG-RKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMG 713
VSGGV A TL FM G KE F+ LL+ MG +C + G+G +AK+ NNM +G
Sbjct: 137 VSGGVGAATAGTLTFMVGAENKELFQECKNLLQHMGKNIANCEKPGAGSIAKICNNMALG 196
Query: 714 ITGMAXAECMXMGIKMGLXPKVLLDVLNNSSXRSWST 824
I +A AE + +G K+G+ PKVL ++N +S R WS+
Sbjct: 197 IEMIAVAEAISLGKKLGIDPKVLSSIMNTASGRCWSS 233
>UniRef50_Q83D20 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=9;
Proteobacteria|Rep: 3-hydroxyisobutyrate dehydrogenase -
Coxiella burnetii
Length = 297
Score = 152 bits (368), Expect = 1e-35
Identities = 79/212 (37%), Positives = 121/212 (57%)
Frame = +3
Query: 186 VAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGVTPANSIXXXXXXXXXXXS 365
+ F+GLG+MG M NL+K V+ YD +A+ A K G T A S +
Sbjct: 4 IGFIGLGHMGQPMVNNLIKNNCLVKVYDVIDEAVEKAVKTGATAAASPAEVAEEADVVFT 63
Query: 366 ILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAPVSG 545
+L ++ V + L G+ A + ++ IDSS+ID +++ A ++G+ DAPVSG
Sbjct: 64 MLQTSDQVRNCCLSAKGIFATINRQAIYIDSSSIDIEGSRELHKEAKKRGISMLDAPVSG 123
Query: 546 GVMGAQNATLAFMAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMGITGM 725
GV A+ A L FM GG KEDFER+ +L ++G K + G G+G AK+ NNML+GI+ +
Sbjct: 124 GVAAAEAAGLTFMVGGEKEDFERAKRVLGILGKKIIYAGSDGAGAAAKICNNMLLGISMI 183
Query: 726 AXAECMXMGIKMGLXPKVLLDVLNNSSXRSWS 821
A +E + K+GL P+ L ++ +N+S WS
Sbjct: 184 AVSEAFVLADKLGLDPQKLFEISSNASGECWS 215
>UniRef50_Q55702 Cluster: Uncharacterized oxidoreductase slr0229;
n=4; Cyanobacteria|Rep: Uncharacterized oxidoreductase
slr0229 - Synechocystis sp. (strain PCC 6803)
Length = 290
Score = 150 bits (364), Expect = 4e-35
Identities = 82/214 (38%), Positives = 118/214 (55%), Gaps = 2/214 (0%)
Frame = +3
Query: 186 VAFLGLGNMGGFMAANLVKKGFTVRGYDPS--KDALNAAAKNGVTPANSIXXXXXXXXXX 359
+A GLG MG MA NLVK G+ GY+ + + ++ AAK GV SI
Sbjct: 6 IAVFGLGVMGSPMAQNLVKNGYQTVGYNRTLERPSVQEAAKAGVKVVTSIAVAAANADII 65
Query: 360 XSILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAPV 539
+ + K V + LG G+ +AK +L+ID STI ++ +GL F DAPV
Sbjct: 66 LTCVGDEKDVQQLILGSGGIAEYAKPQALIIDCSTIGKTAAYELATNLKLQGLRFLDAPV 125
Query: 540 SGGVMGAQNATLAFMAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMGIT 719
+GG +GA N TL M GG DFE +LP+LK +G K HCG GSGQ KL N +L GI
Sbjct: 126 TGGDVGAINGTLTIMVGGDISDFEEALPVLKSIGEKIVHCGPSGSGQAVKLCNQVLCGIH 185
Query: 720 GMAXAECMXMGIKMGLXPKVLLDVLNNSSXRSWS 821
+A AE + + ++G+ P++++D + + SW+
Sbjct: 186 AIAAAEAIQLSEQLGIAPELVIDTCGSGAAGSWA 219
>UniRef50_A0JUJ6 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=2;
Micrococcineae|Rep: 3-hydroxyisobutyrate dehydrogenase -
Arthrobacter sp. (strain FB24)
Length = 300
Score = 150 bits (363), Expect = 5e-35
Identities = 83/212 (39%), Positives = 119/212 (56%)
Frame = +3
Query: 186 VAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGVTPANSIXXXXXXXXXXXS 365
VA++GLGNMGG M+ANL K G VRG+D + +A+ AA GV P SI +
Sbjct: 4 VAWIGLGNMGGSMSANLAKAGHDVRGFDLNPEAVAAAEAGGVKPVASIAAAVDGADVVFT 63
Query: 366 ILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAPVSG 545
+L + VYLG+DGV+AHA + +LL+DSSTID + + A G F DAPVSG
Sbjct: 64 MLPKGEHARAVYLGEDGVLAHADRRTLLVDSSTIDIASAQALHDAAAAAGFRFVDAPVSG 123
Query: 546 GVMGAQNATLAFMAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMGITGM 725
G+ GA+ TL FM GG + ++ M + G +GQ AK+ NN+++ I
Sbjct: 124 GMSGAKAGTLTFMIGGDAGAVAEATEYIRPMASNIIPTGGPTTGQAAKICNNLMLFINLA 183
Query: 726 AXAECMXMGIKMGLXPKVLLDVLNNSSXRSWS 821
+ AE + ++GL +V D+ + SS SW+
Sbjct: 184 STAEGAVLAERLGLDKQVFWDIASVSSGDSWA 215
>UniRef50_A0UF54 Cluster: 6-phosphogluconate dehydrogenase,
NAD-binding; n=1; Burkholderia multivorans ATCC
17616|Rep: 6-phosphogluconate dehydrogenase, NAD-binding
- Burkholderia multivorans ATCC 17616
Length = 289
Score = 146 bits (353), Expect = 9e-34
Identities = 76/215 (35%), Positives = 116/215 (53%)
Frame = +3
Query: 180 KNVAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGVTPANSIXXXXXXXXXX 359
K V +GLGNMG +A++L + GF V G+D + +++ A GV P S+
Sbjct: 2 KTVGVIGLGNMGRGIASSLKRAGFDVLGFDANAESVRQLADEGVRPCASVAEIASAVDVL 61
Query: 360 XSILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAPV 539
L ++ +V V LG GV +HAK+G ++ID++T DPN +++ G+GF D PV
Sbjct: 62 ILSLPTSAIVEAVVLGDGGVASHAKRGLIVIDTTTADPNSTRKVAAALDAHGIGFIDGPV 121
Query: 540 SGGVMGAQNATLAFMAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMGIT 719
SGG GA AT+ + GG E P+L + AKQ H G G+G V KL NN+L G+
Sbjct: 122 SGGPKGAATATMTMVLGGADEHIAAVQPVLSAISAKQVHVGPAGAGHVTKLLNNLLTGVH 181
Query: 720 GMAXAECMXMGIKMGLXPKVLLDVLNNSSXRSWST 824
+ +E + G+ L++ L+ S R+ +T
Sbjct: 182 LLVTSEAVRAAEAAGVDKARLIEALSGGSGRNSAT 216
>UniRef50_A3I4V2 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=1;
Bacillus sp. B14905|Rep: 3-hydroxyisobutyrate
dehydrogenase - Bacillus sp. B14905
Length = 316
Score = 144 bits (350), Expect = 2e-33
Identities = 78/214 (36%), Positives = 123/214 (57%), Gaps = 1/214 (0%)
Frame = +3
Query: 177 DKNVAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGVTPANSIXXXXXXXXX 356
++ + F+GLGNMG M+ NL+K + V G+D + A+ + G S
Sbjct: 21 NRKLGFIGLGNMGLPMSINLLKANYEVYGFDTNAKAVELFTEAGGIGLASAKDVAKQCDV 80
Query: 357 XXSILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAP 536
+ L + ++V VYL ++G++ HAKKG+LL+D ST++P++ + A GL + AP
Sbjct: 81 VMTSLPTPQIVEMVYLSEEGIIHHAKKGALLVDFSTVNPDLNDSLHKEASTLGLRYLGAP 140
Query: 537 VSGGVMGAQNATLAFMAGGRKEDFERSLPLLKVMGAKQFHCGQIGS-GQVAKLTNNMLMG 713
VSGGV+GA NATL M GG K+D++ + + ++G +H G S G KL NN+++G
Sbjct: 141 VSGGVIGAVNATLTIMVGGGKDDYDSASEIFGIVGKNIYHLGLSSSVGTRLKLLNNLMIG 200
Query: 714 ITGMAXAECMXMGIKMGLXPKVLLDVLNNSSXRS 815
A AE + +G KMG+ L +VL+NS +S
Sbjct: 201 FYTEAVAETIVLGEKMGIDADTLYEVLSNSYGQS 234
>UniRef50_Q0QLF5 Cluster: 2-hydroxymethyl glutarate dehydrogenase;
n=1; Eubacterium barkeri|Rep: 2-hydroxymethyl glutarate
dehydrogenase - Eubacterium barkeri (Clostridium
barkeri)
Length = 301
Score = 144 bits (349), Expect = 3e-33
Identities = 71/212 (33%), Positives = 117/212 (55%)
Frame = +3
Query: 186 VAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGVTPANSIXXXXXXXXXXXS 365
+ F+GLG MG MA NL+K+G TV +D + + A G + +
Sbjct: 7 IGFIGLGAMGKPMAINLLKEGVTVYAFDLMEANVAAVVAQGAQACENNQKVAAASDIIFT 66
Query: 366 ILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAPVSG 545
L + +V V G GV++ K G++++D S++ P+ ++ +A EKG+ + DAPVSG
Sbjct: 67 SLPNAGIVETVMNGPGGVLSACKAGTVIVDMSSVSPSSTLKMAKVAAEKGIDYVDAPVSG 126
Query: 546 GVMGAQNATLAFMAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMGITGM 725
G GA+ TL M G + FE+ P+L V+G +H G G+G K+ NN+L+G
Sbjct: 127 GTKGAEAGTLTIMVGASEAVFEKIQPVLSVIGKDIYHVGDTGAGDAVKIVNNLLLGCNMA 186
Query: 726 AXAECMXMGIKMGLXPKVLLDVLNNSSXRSWS 821
+ AE + +G+K GL P+ + +++ SS RS++
Sbjct: 187 SLAEALVLGVKCGLKPETMQEIIGKSSGRSYA 218
>UniRef50_A6NVP0 Cluster: Putative uncharacterized protein; n=1;
Bacteroides capillosus ATCC 29799|Rep: Putative
uncharacterized protein - Bacteroides capillosus ATCC
29799
Length = 306
Score = 144 bits (349), Expect = 3e-33
Identities = 75/212 (35%), Positives = 113/212 (53%)
Frame = +3
Query: 186 VAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGVTPANSIXXXXXXXXXXXS 365
+ F+GLG MG MA NL+ G+ V +D + A+ G S
Sbjct: 8 IGFIGLGAMGRPMATNLLTAGYEVHAFDVVEAAVKEMEGKGAIGHPSAGEMAGHVDVIIC 67
Query: 366 ILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAPVSG 545
L + K+V GK+GV + K+G+++ID S++ PN K + A EKG+ + DAPVSG
Sbjct: 68 SLPNAKIVEGTMCGKNGVFENCKEGTVIIDMSSVAPNTTKAMAKKAAEKGIHYIDAPVSG 127
Query: 546 GVMGAQNATLAFMAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMGITGM 725
GV GA TL M G E F + P+ V+G +H G+ G G K+ NN+L+G
Sbjct: 128 GVSGAAAGTLTIMVGADDETFNKVKPIFDVLGKNIYHVGEAGGGDAIKMVNNLLLGCNMA 187
Query: 726 AXAECMXMGIKMGLXPKVLLDVLNNSSXRSWS 821
A AE + +G+K GL + + +V++ SS RS++
Sbjct: 188 ALAEALTLGVKCGLSVETMKEVISVSSGRSYA 219
>UniRef50_Q4FMJ3 Cluster: 6-phosphogluconate dehydrogenase; n=2;
Candidatus Pelagibacter ubique|Rep: 6-phosphogluconate
dehydrogenase - Pelagibacter ubique
Length = 289
Score = 143 bits (347), Expect = 5e-33
Identities = 74/206 (35%), Positives = 124/206 (60%)
Frame = +3
Query: 180 KNVAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGVTPANSIXXXXXXXXXX 359
+N++F+G+G MG MA NL+K GF +R Y+ S+D + + G + SI
Sbjct: 2 QNISFIGIGLMGFPMAKNLLKSGFNLRAYNRSQDKADRLKEFGAEISTSIKDVVTNSDVI 61
Query: 360 XSILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAPV 539
++LT + V V +G D +++ K+G+ +ID S+++P + K+ F I EK + + DAPV
Sbjct: 62 ITMLTDDAAVEKV-MGSDEFISNIKEGATVIDMSSVNPVITKKYFKILKEKNINYLDAPV 120
Query: 540 SGGVMGAQNATLAFMAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMGIT 719
SGG +GA+ A+LA M GG +E F++ LLK++G G + SGQ++KL N +++G+T
Sbjct: 121 SGGTIGAEEASLAIMVGGDEETFKQCYDLLKILGNPTL-VGPVTSGQISKLANQIIVGVT 179
Query: 720 GMAXAECMXMGIKMGLXPKVLLDVLN 797
A AE + + K G P +++ L+
Sbjct: 180 IGAVAEAVTLCEKSGTNPNKMIEALS 205
>UniRef50_Q1AVA4 Cluster: 2-hydroxy-3-oxopropionate reductase; n=6;
Bacteria|Rep: 2-hydroxy-3-oxopropionate reductase -
Rubrobacter xylanophilus (strain DSM 9941 / NBRC 16129)
Length = 309
Score = 143 bits (346), Expect = 6e-33
Identities = 79/217 (36%), Positives = 122/217 (56%), Gaps = 1/217 (0%)
Frame = +3
Query: 147 AARRAYSSNTDKNVAFLGLGNMGGFMAANLVKKGFTVRGYDPS-KDALNAAAKNGVTPAN 323
A R + + V F+GLG MG MA NL++ G+++ ++ + + A A + G A
Sbjct: 4 APRERRKAGMAEKVGFIGLGIMGRPMAENLIRAGYSLTVHNRTHQKAEEFAQQTGARTAK 63
Query: 324 SIXXXXXXXXXXXSILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIA 503
S ++L + V V G+ GV+ ++GSLLID STI P V +Q+ A
Sbjct: 64 SPKEVAGQSDIIITMLPDSPDVESVVAGEGGVLEGMREGSLLIDMSTISPAVARQLAAKA 123
Query: 504 LEKGLGFTDAPVSGGVMGAQNATLAFMAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQV 683
E+G DAPVSGG +GA+ TL+ M GG +EDF R+ PL +VMG H G G+GQ+
Sbjct: 124 RERGASMLDAPVSGGDVGAREGTLSIMVGGSEEDFGRARPLFEVMGKTVTHVGPSGAGQI 183
Query: 684 AKLTNNMLMGITGMAXAECMXMGIKMGLXPKVLLDVL 794
K N +++G+T A E + +G++ G+ P+ + +VL
Sbjct: 184 VKAANQIVVGLTIEAVCEALVLGLRGGVEPQKIFEVL 220
>UniRef50_Q9SUC0 Cluster: Probable 3-hydroxyisobutyrate
dehydrogenase, mitochondrial precursor; n=13;
Magnoliophyta|Rep: Probable 3-hydroxyisobutyrate
dehydrogenase, mitochondrial precursor - Arabidopsis
thaliana (Mouse-ear cress)
Length = 347
Score = 142 bits (345), Expect = 8e-33
Identities = 80/241 (33%), Positives = 129/241 (53%), Gaps = 12/241 (4%)
Frame = +3
Query: 138 LYTAARRAYSSNTDKNVAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGVTP 317
L+ + + +SN +NV F+GLGNMG M NL++ G+ V +D ++D + + GV+
Sbjct: 24 LHRFSSSSQNSNQFQNVGFIGLGNMGFRMVNNLIRAGYKVTVHDINRDVMKMFTEMGVSS 83
Query: 318 ANSIXXXXXXXXXXXSILTSNKVVLDVYLGKDGVVAHAK--KGSLLIDSSTIDPNVPKQI 491
+ ++L S+ V+DVY G +G++ + +L IDSSTIDP ++I
Sbjct: 84 RETPYEVAQDSEVVITMLPSSSHVMDVYTGTNGLLLGENDIRPALFIDSSTIDPQTTRKI 143
Query: 492 FPIALEKGLG----------FTDAPVSGGVMGAQNATLAFMAGGRKEDFERSLPLLKVMG 641
L DAPVSGGV+ A+ TL FM GG ++ + + P+L+ MG
Sbjct: 144 SLAVSNCNLKEKRDNWEKPVMLDAPVSGGVLAAEAGTLTFMVGGPEDAYLAARPILQSMG 203
Query: 642 AKQFHCGQIGSGQVAKLTNNMLMGITGMAXAECMXMGIKMGLXPKVLLDVLNNSSXRSWS 821
+CG G+G AK+ NN+ M ++ + +E + +G +G+ L +VLN SS R WS
Sbjct: 204 RTSIYCGGSGNGSAAKICNNLAMAVSMLGTSEALALGQSLGISASTLTEVLNTSSGRCWS 263
Query: 822 T 824
+
Sbjct: 264 S 264
>UniRef50_Q9A8J9 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=24;
Alphaproteobacteria|Rep: 3-hydroxyisobutyrate
dehydrogenase - Caulobacter crescentus (Caulobacter
vibrioides)
Length = 298
Score = 141 bits (342), Expect = 2e-32
Identities = 82/223 (36%), Positives = 112/223 (50%)
Frame = +3
Query: 186 VAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGVTPANSIXXXXXXXXXXXS 365
+AF+GLGNMGG MAAN K VR +D S A+ A G A S+ +
Sbjct: 4 IAFIGLGNMGGGMAANQAKAQHQVRAFDLSAAAVERAVAAGCLAAASVAEAVAEAEIVIT 63
Query: 366 ILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAPVSG 545
+L + V VY + ++ +A K +LLID STID + + + A E G F DAPVSG
Sbjct: 64 MLPAGPHVRAVYA--EQILPNAPKSALLIDCSTIDVDSARVVARQAAEAGFRFADAPVSG 121
Query: 546 GVMGAQNATLAFMAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMGITGM 725
G+M A+ TLAFM G DF L M H G G+GQ AK+ NNML+G++ +
Sbjct: 122 GIMAAEAGTLAFMVGCEASDFAAVEAALAPMSRVTIHAGDHGAGQAAKICNNMLLGVSML 181
Query: 726 AXAECMXMGIKMGLXPKVLLDVLNNSSXRSWSTXXVLSXPRTG 854
E + K+GL ++ + SS + WS P G
Sbjct: 182 GTCEAFALAEKLGLAADRFFEIASKSSGQCWSITSYCPVPGVG 224
>UniRef50_Q8KL12 Cluster: Probable 6-phosphogluconate dehydrogenase
protein; n=1; Rhizobium etli CFN 42|Rep: Probable
6-phosphogluconate dehydrogenase protein - Rhizobium
etli (strain CFN 42 / ATCC 51251)
Length = 294
Score = 141 bits (342), Expect = 2e-32
Identities = 81/220 (36%), Positives = 119/220 (54%)
Frame = +3
Query: 165 SSNTDKNVAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGVTPANSIXXXXX 344
S + VAF+GLG MGG MA +L+ F V G+D S +A A G PA ++
Sbjct: 2 SPRKNLRVAFIGLGAMGGPMAQHLLSAQFEVTGFDLSAEARERFAAVGGVPAETVAEAFN 61
Query: 345 XXXXXXSILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGF 524
++L + K+V D L KDG +L+ID S+ PN +++ +KGL
Sbjct: 62 GADVAVTMLPNGKIVQDA-LFKDGAWQSLSADALVIDMSSSAPNDTRELAERLHQKGLRL 120
Query: 525 TDAPVSGGVMGAQNATLAFMAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNM 704
DAPVSGGV A +L MAGG +D +++ P+L MG + F G IGSG K NN
Sbjct: 121 VDAPVSGGVKRAVEGSLTIMAGGASDDIDQADPILCAMGGQIFRTGPIGSGHAMKAINNF 180
Query: 705 LMGITGMAXAECMXMGIKMGLXPKVLLDVLNNSSXRSWST 824
+ G +A E + +G GL P+ ++D+LN+SS ++ +T
Sbjct: 181 VSGAGVLAAIEGVLLGRTFGLDPRTIVDILNSSSGKNNAT 220
>UniRef50_Q4ZQL5 Cluster: 3-hydroxyisobutyrate dehydrogenase
precursor; n=11; Proteobacteria|Rep:
3-hydroxyisobutyrate dehydrogenase precursor -
Pseudomonas syringae pv. syringae (strain B728a)
Length = 296
Score = 141 bits (341), Expect = 3e-32
Identities = 77/210 (36%), Positives = 112/210 (53%)
Frame = +3
Query: 195 LGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGVTPANSIXXXXXXXXXXXSILT 374
+GLGNMGG MAA L KGF V G+D S+ AL A GV P L
Sbjct: 8 IGLGNMGGGMAATLAGKGFDVSGFDLSQAALAQAESKGVKPVADRTQLIQGVDILILSLP 67
Query: 375 SNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAPVSGGVM 554
+ V V LG G+ +KG +++D++T P + +++ + G+ F DAPVSGG
Sbjct: 68 KAEHVESVCLGAGGINEVGRKGLIVVDTTTSTPEMSRKVAAELAKNGIAFIDAPVSGGPK 127
Query: 555 GAQNATLAFMAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMGITGMAXA 734
GA +++ + G D R++P+L+ M + H GQ G+G VAK+ NNML ++ A
Sbjct: 128 GAATGSMSMVIGAEDADLARAMPVLEGMSGTRVHVGQCGAGNVAKIANNMLAACHLISTA 187
Query: 735 ECMXMGIKMGLXPKVLLDVLNNSSXRSWST 824
E + M + G+ P+ LL LN S RS +T
Sbjct: 188 EAVAMAARAGVDPEKLLQGLNAGSGRSGAT 217
>UniRef50_Q9K9L1 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=2;
Bacillus|Rep: 3-hydroxyisobutyrate dehydrogenase -
Bacillus halodurans
Length = 299
Score = 140 bits (340), Expect = 3e-32
Identities = 81/223 (36%), Positives = 111/223 (49%), Gaps = 4/223 (1%)
Frame = +3
Query: 180 KNVAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGVTPANSIXXXXXXXXXX 359
+ V F+GLG MG M +LV KGF S+ + A + G S
Sbjct: 3 QKVGFVGLGTMGLPMTKHLVDKGFETYVKSRSRGPIEEAIQYGAIEVESYKELMETADIV 62
Query: 360 XSILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAPV 539
+ L + V+DVY G+DG++A +G +LID ST+D ++ EKG F DAPV
Sbjct: 63 MTCLPLPETVIDVYEGEDGLIAGLSQGKILIDHSTVDRETNVRVAEQIKEKGGAFLDAPV 122
Query: 540 SGGVMGAQNATLAFMAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMGIT 719
SGG MGA+ TL M GG + FERS +L G H G IGSG V KL NNM++G+
Sbjct: 123 SGGPMGAKAGTLTIMCGGEADSFERSKEVLGAYGDYIVHVGPIGSGTVVKLANNMVIGVH 182
Query: 720 GMAXAECMXMGIKMGLXPKVLLDVLNNSSXRS----WSTXXVL 836
EC K G+ P + +++ S+ S WS +L
Sbjct: 183 QAVLGECYLFVEKAGVDPAIAYEIIKRSAGFSKSMEWSVDAIL 225
>UniRef50_A1SIN3 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=1;
Nocardioides sp. JS614|Rep: 3-hydroxyisobutyrate
dehydrogenase - Nocardioides sp. (strain BAA-499 /
JS614)
Length = 308
Score = 140 bits (339), Expect = 4e-32
Identities = 77/217 (35%), Positives = 115/217 (52%), Gaps = 3/217 (1%)
Frame = +3
Query: 180 KNVAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGVTPANSIXXXXXXXXXX 359
+ +AF+GLGNMG MA NL+ GF V G+D +A+ G+ A +
Sbjct: 2 ERIAFIGLGNMGNSMAKNLIAAGFDVVGFDADSRTNQRSAETGIPVAADVVDAVTGADVV 61
Query: 360 XSILTSNKVVLDVYLG---KDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTD 530
++L + ++ V LG + GV+ + G+L+IDSS+ID + A G+ F D
Sbjct: 62 ITMLPNGDILRQVLLGAGAESGVLNYLAPGALVIDSSSIDVANCLAVHESAASAGIAFLD 121
Query: 531 APVSGGVMGAQNATLAFMAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLM 710
APVSGGV GA TL FM GG + R+ PL + MG K G +GQ K+ N M+
Sbjct: 122 APVSGGVGGAAAGTLTFMVGGDEAHVRRAWPLFEAMGKKVVRVGGPSTGQAVKMCNQMIY 181
Query: 711 GITGMAXAECMXMGIKMGLXPKVLLDVLNNSSXRSWS 821
+ +A AE + K+G+ PK+L +V+ +SS W+
Sbjct: 182 ASSLVAVAEAFSLADKLGVAPKMLFEVVTSSSGDCWA 218
>UniRef50_Q67QX0 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=1;
Symbiobacterium thermophilum|Rep: 3-hydroxyisobutyrate
dehydrogenase - Symbiobacterium thermophilum
Length = 294
Score = 138 bits (334), Expect = 2e-31
Identities = 79/211 (37%), Positives = 112/211 (53%)
Frame = +3
Query: 183 NVAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGVTPANSIXXXXXXXXXXX 362
N+ F+GLG MG MA NL++ G TV Y+ S+ ++ G A
Sbjct: 4 NLGFIGLGRMGRHMARNLIRAGHTVTLYNRSQAVVDELVAEGGRRAAGPAEVARDARVLF 63
Query: 363 SILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAPVS 542
+ LT+ VV + + A+ G + +D STI K+I + EKG+ F DAPVS
Sbjct: 64 TCLTTPDVVESILRQ---ALEGAQPGDIFVDHSTIGVRDAKRIAAMCAEKGVQFIDAPVS 120
Query: 543 GGVMGAQNATLAFMAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMGITG 722
GG GA+ TL M GG + FE LP L+V G H G +G+G VAKL NN+L+GI
Sbjct: 121 GGPWGAEAGTLTIMCGGDRAAFEAVLPYLQVEGKAIHHLGPVGAGSVAKLCNNLLVGIHT 180
Query: 723 MAXAECMXMGIKMGLXPKVLLDVLNNSSXRS 815
A AE +G K G+ PK L ++++N++ S
Sbjct: 181 AAMAEAFVLGTKAGVDPKALYEIISNATGHS 211
>UniRef50_O34948 Cluster: Uncharacterized oxidoreductase ykwC; n=19;
cellular organisms|Rep: Uncharacterized oxidoreductase
ykwC - Bacillus subtilis
Length = 288
Score = 138 bits (334), Expect = 2e-31
Identities = 75/214 (35%), Positives = 115/214 (53%)
Frame = +3
Query: 180 KNVAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGVTPANSIXXXXXXXXXX 359
K + F+GLG MG MA++++ G V Y +K+ + + G +++
Sbjct: 3 KTIGFIGLGVMGKSMASHILNDGHPVLVYTRTKEKAESILQKGAIWKDTVKDLSKEADVI 62
Query: 360 XSILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAPV 539
+++ V +VY G +G++ +AK+G+ LID +T P++ K+I A EK L DAPV
Sbjct: 63 ITMVGYPSDVEEVYFGSNGIIENAKEGAYLIDMTTSKPSLAKKIAEAAKEKALFALDAPV 122
Query: 540 SGGVMGAQNATLAFMAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMGIT 719
SGG +GAQN TLA M GG KE FE +P+ +MG + G GSGQ K+ N + +
Sbjct: 123 SGGDIGAQNGTLAIMVGGEKEAFEACMPIFSLMGENIQYQGPAGSGQHTKMCNQIAIAAG 182
Query: 720 GMAXAECMXMGIKMGLXPKVLLDVLNNSSXRSWS 821
+ AE M K GL P+ +L + + SWS
Sbjct: 183 MIGVAEAMAYAQKSGLEPENVLKSITTGAAGSWS 216
>UniRef50_Q1V2R0 Cluster: MmsB-like protein; n=2; Candidatus
Pelagibacter ubique|Rep: MmsB-like protein - Candidatus
Pelagibacter ubique HTCC1002
Length = 308
Score = 134 bits (325), Expect = 2e-30
Identities = 72/213 (33%), Positives = 117/213 (54%)
Frame = +3
Query: 183 NVAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGVTPANSIXXXXXXXXXXX 362
++AF+G+GNMG MA LVK G V+ +D S + + A ++G+ ++I
Sbjct: 4 HIAFIGVGNMGNPMADQLVKAGKEVKAFDVSPEVIKIAKESGLNVVSTIDELLDGASTVI 63
Query: 363 SILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAPVS 542
S+L K V +YLG G++ K L+ID STID ++ + + G+ DAPV+
Sbjct: 64 SMLPEGKHVRSLYLGDKGILNKIPKECLIIDCSTIDIETSLELGNESKKLGIKMIDAPVT 123
Query: 543 GGVMGAQNATLAFMAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMGITG 722
GGVMGA+ L F+ GG E + PL +MG K H G GSG K+ NNM +GI+
Sbjct: 124 GGVMGARIGKLNFLVGGSDEAVALAKPLFDIMGQKILHAGVQGSGVGVKICNNMSLGISM 183
Query: 723 MAXAECMXMGIKMGLXPKVLLDVLNNSSXRSWS 821
+A +E + + ++ + K + +++ +S +W+
Sbjct: 184 IAASESLMLAKRLKMDIKKVHEIIKAASGNNWA 216
>UniRef50_A2SP40 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=1;
Methylibium petroleiphilum PM1|Rep: 3-hydroxyisobutyrate
dehydrogenase - Methylibium petroleiphilum (strain PM1)
Length = 297
Score = 134 bits (325), Expect = 2e-30
Identities = 79/213 (37%), Positives = 116/213 (54%), Gaps = 1/213 (0%)
Frame = +3
Query: 180 KNVAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGVTPANSIXXXXXXXXXX 359
K + +GLGN+GG M L+ +G V G+D S A AAA++G S
Sbjct: 2 KEIGLIGLGNIGGGMCRRLLDRGIGVVGFDLSPAATKAAAEHGARIEVSPAAVAQQVDVV 61
Query: 360 XSILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAPV 539
+ L + +V DVYLGK G+VA A+ GS LI++STIDPN +++ A + G+ D +
Sbjct: 62 VTSLPNPPIVRDVYLGKQGLVAQARPGSTLIETSTIDPNTIREVAQAATKSGIRILDIAL 121
Query: 540 SGGVMGAQNATLAFMAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNML-MGI 716
SG A L F GG E ++ L LL+V+ K G IG+ + KL NN++ +G
Sbjct: 122 SGEPPQAVLGELVFQVGGPDELIDQHLELLQVLAKKINRTGGIGTAKTVKLVNNLMSLGN 181
Query: 717 TGMAXAECMXMGIKMGLXPKVLLDVLNNSSXRS 815
+A AE +G+K G+ PK L ++L+ S RS
Sbjct: 182 VAVA-AEAFVLGVKCGMEPKRLYEILSVSGGRS 213
>UniRef50_A0GVR3 Cluster: 6-phosphogluconate dehydrogenase,
NAD-binding; n=1; Burkholderia phytofirmans PsJN|Rep:
6-phosphogluconate dehydrogenase, NAD-binding -
Burkholderia phytofirmans PsJN
Length = 311
Score = 133 bits (322), Expect = 5e-30
Identities = 72/211 (34%), Positives = 112/211 (53%)
Frame = +3
Query: 186 VAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGVTPANSIXXXXXXXXXXXS 365
+ F+G G MG M +NL+K V D ++DA + A G T A ++ +
Sbjct: 3 IGFIGAGRMGHRMISNLLKGSHAVLVLDGARDARDRVASLGATLAMNLADLVTGQDIVIT 62
Query: 366 ILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAPVSG 545
+L + V L VY G G+ + +LL++ ST+D +++ A G DAP++G
Sbjct: 63 MLPTPDVSLSVYEGAGGLFSITPPETLLLECSTVDVKTIERLGEGARASGTQLIDAPLTG 122
Query: 546 GVMGAQNATLAFMAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMGITGM 725
G+ GA ATL FM GG +E E + P L+ MG++ H G+ GSG KL NNM+ M
Sbjct: 123 GIEGAALATLTFMVGGSEEQLEYARPALQSMGSRIVHAGRFGSGTKLKLVNNMICATNLM 182
Query: 726 AXAECMXMGIKMGLXPKVLLDVLNNSSXRSW 818
+E + +G+K+GL + + DV+ N + SW
Sbjct: 183 VASEALTLGLKLGLDAQPMYDVIANGTGASW 213
>UniRef50_Q41DK0 Cluster: 6-phosphogluconate dehydrogenase,
NAD-binding; n=2; Bacillaceae|Rep: 6-phosphogluconate
dehydrogenase, NAD-binding - Exiguobacterium sibiricum
255-15
Length = 293
Score = 133 bits (321), Expect = 7e-30
Identities = 73/214 (34%), Positives = 115/214 (53%)
Frame = +3
Query: 180 KNVAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGVTPANSIXXXXXXXXXX 359
K + F+GLG MG M NL+K GF+V+GY+ +K+ ++G ++I
Sbjct: 3 KTIGFIGLGVMGQGMVRNLLKAGFSVKGYNRTKEKGLPLEQDGAVIVDTIQEAVTDVDVV 62
Query: 360 XSILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAPV 539
SI+ + V ++YL +DG++A A G+++ID +T P + +I A + GL DAPV
Sbjct: 63 ISIVGYPQDVEEIYLAEDGILASANPGTIVIDMTTSSPALAIRIAEQAAQTGLHALDAPV 122
Query: 540 SGGVMGAQNATLAFMAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMGIT 719
+GG +GA+N TLA + GG + F+ PL + MG G G GQ AKL N + + +
Sbjct: 123 TGGDLGAKNGTLAILVGGEEAAFDTVKPLFEAMGKSIARFGGPGQGQSAKLANQIAIAGS 182
Query: 720 GMAXAECMXMGIKMGLXPKVLLDVLNNSSXRSWS 821
+ AE + K G+ P + + + S SWS
Sbjct: 183 MIGTAEMLLFVTKSGIDPTQFVATIKSGSAGSWS 216
>UniRef50_A5V0D4 Cluster: 6-phosphogluconate dehydrogenase,
NAD-binding; n=4; Chloroflexaceae|Rep:
6-phosphogluconate dehydrogenase, NAD-binding -
Roseiflexus sp. RS-1
Length = 303
Score = 133 bits (321), Expect = 7e-30
Identities = 74/213 (34%), Positives = 112/213 (52%)
Frame = +3
Query: 180 KNVAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGVTPANSIXXXXXXXXXX 359
+ V F+GLG MG MA N++K GF +R ++ + ++ A G PA+S
Sbjct: 5 ERVGFIGLGIMGRGMARNILKAGFPLRVWNRTASRMDELAAEGAGPASSPGDLAFHSDII 64
Query: 360 XSILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAPV 539
+ ++ V V LG+ GV+ A+ GSL+ID STI P ++I E+ + DAPV
Sbjct: 65 ITCVSDTPDVEQVLLGEGGVIHGARPGSLVIDMSTISPRATQRIAAHLAERHIHMLDAPV 124
Query: 540 SGGVMGAQNATLAFMAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMGIT 719
SGG GA TL+ M GG FER+LP+ + MG H G IG+GQ KL N +L+
Sbjct: 125 SGGSEGAARGTLSIMVGGDVTQFERALPVFQAMGTTITHLGPIGAGQTTKLVNQILVVGH 184
Query: 720 GMAXAECMXMGIKMGLXPKVLLDVLNNSSXRSW 818
+A +E + G+ + L+ ++ + SW
Sbjct: 185 ALAMSEALLFAQAGGVDLRKALEAVSGGAAGSW 217
>UniRef50_Q1QWU9 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=1;
Chromohalobacter salexigens DSM 3043|Rep:
3-hydroxyisobutyrate dehydrogenase - Chromohalobacter
salexigens (strain DSM 3043 / ATCC BAA-138 / NCIMB13768)
Length = 310
Score = 132 bits (319), Expect = 1e-29
Identities = 78/213 (36%), Positives = 109/213 (51%)
Frame = +3
Query: 177 DKNVAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGVTPANSIXXXXXXXXX 356
D N+ +GLG MGG MA L GFTV G D + A + A G++ +
Sbjct: 10 DMNIVVIGLGQMGGNMAMTLHAAGFTVTGTDVADAARDNLAARGLS-VTRLDALPEADVY 68
Query: 357 XXSILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAP 536
S+ TS V +V G++ A KGS+++D+ST DP V +++ +E GL + DAP
Sbjct: 69 LLSLPTSAHV-REVIETSPGLLQRAPKGSVIVDTSTSDPAVTRELAGKVVEAGLEWLDAP 127
Query: 537 VSGGVMGAQNATLAFMAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMGI 716
VSGG GA + L + GG ER P+L+ M A+ H G GSG V KL NN L
Sbjct: 128 VSGGPAGAASGALGMLLGGESATIERLAPMLEAMSARHTHVGPAGSGHVVKLANNYLCAA 187
Query: 717 TGMAXAECMXMGIKMGLXPKVLLDVLNNSSXRS 815
+ AE + + + G+ P L LN+ S RS
Sbjct: 188 HLLTTAEAVTLAARAGVDPAACLAGLNSGSGRS 220
>UniRef50_Q8ES28 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=13;
Bacillaceae|Rep: 3-hydroxyisobutyrate dehydrogenase -
Oceanobacillus iheyensis
Length = 299
Score = 130 bits (315), Expect = 4e-29
Identities = 73/211 (34%), Positives = 113/211 (53%), Gaps = 1/211 (0%)
Frame = +3
Query: 186 VAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGVTPANSIXXXXXXXXXXXS 365
+ F+GLGNMG M+ L+ G+ V G+D +++ K+G A S +
Sbjct: 4 IGFIGLGNMGLPMSIGLMNSGYEVIGFDVNEERSLLFKKSGGNIALSSADLVAESDVILT 63
Query: 366 ILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAPVSG 545
L SNK V VYL K G++ H ++ID+ST+ P + +Q+ E+ + F APVSG
Sbjct: 64 SLPSNKAVEAVYLNKGGLLDHCNSSQVVIDTSTVAPELNQQLEASLSERSIPFLAAPVSG 123
Query: 546 GVMGAQNATLAFMAGGRKEDFERSLPLLKVMGAKQFHCG-QIGSGQVAKLTNNMLMGITG 722
GV+GA+N TL M GG++E F++ +L V+G FH G QI G KL NN+L+G
Sbjct: 124 GVVGAENQTLTVMVGGKEETFQKVKDILNVIGGNVFHVGEQIDKGTTVKLINNLLIGFYT 183
Query: 723 MAXAECMXMGIKMGLXPKVLLDVLNNSSXRS 815
+E + + + + L ++N S +S
Sbjct: 184 AGVSEALQIANQKDIDLNDLFSMMNVSYGQS 214
>UniRef50_Q58PL4 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=1;
uncultured proteobacterium DelRiverFos06H03|Rep:
3-hydroxyisobutyrate dehydrogenase - uncultured
proteobacterium DelRiverFos06H03
Length = 299
Score = 130 bits (315), Expect = 4e-29
Identities = 71/209 (33%), Positives = 110/209 (52%)
Frame = +3
Query: 192 FLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGVTPANSIXXXXXXXXXXXSIL 371
F+G+GNMG MAANLVK G+ V +D S+ G T S+ + L
Sbjct: 10 FIGVGNMGNPMAANLVKAGYPVTVFDVSRAKAENLIALGATWVGSLAEGAVNADVVMASL 69
Query: 372 TSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAPVSGGV 551
V +V LG+ GV+AH K G+ +ID+ST + +++ +A KG+ F +APV+ V
Sbjct: 70 PGPVQVREVMLGEQGVLAHVKAGATVIDTSTSAVELVQELVALAKSKGVDFLEAPVTNAV 129
Query: 552 MGAQNATLAFMAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMGITGMAX 731
A L+ GG K+ FE+ P+ V+G K FH G+ G+G KL N+L ++ A
Sbjct: 130 DMAALGRLSIFVGGDKDCFEKHKPIFDVIGEKIFHVGEPGNGATIKLLTNLLWFVSAAAI 189
Query: 732 AECMXMGIKMGLXPKVLLDVLNNSSXRSW 818
E + +G K G+ + + + +S+ SW
Sbjct: 190 GEGLMLGAKAGIPLHTVWEAIKSSAGNSW 218
>UniRef50_Q0SBQ9 Cluster: 2-hydroxy-3-oxopropionate reductase; n=12;
Actinomycetales|Rep: 2-hydroxy-3-oxopropionate reductase
- Rhodococcus sp. (strain RHA1)
Length = 294
Score = 130 bits (315), Expect = 4e-29
Identities = 77/203 (37%), Positives = 103/203 (50%)
Frame = +3
Query: 186 VAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGVTPANSIXXXXXXXXXXXS 365
+AF+GLG MG MA NL K G V GY+ D A + G T A+SI
Sbjct: 4 IAFIGLGIMGSPMACNLAKAGHQVVGYNLIPDRTAALVEAGGTAADSIAKAVAGADVVAV 63
Query: 366 ILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAPVSG 545
++ + V V G+DGV H G+L+ID S+I P+V + A E+G DAPVSG
Sbjct: 64 MVPDSPDVQAVLTGEDGVFEHTPSGALIIDFSSIRPDVTTALAAQATERGFRLIDAPVSG 123
Query: 546 GVMGAQNATLAFMAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMGITGM 725
G GA NA L+ M GG EDFE + P+L V+G H G GSGQ K N +++
Sbjct: 124 GEAGAVNAALSIMVGGAPEDFESARPILDVVGKTVVHVGPNGSGQTVKAANQLIVAGNIQ 183
Query: 726 AXAECMXMGIKMGLXPKVLLDVL 794
AE + G+ ++VL
Sbjct: 184 LLAEAIIFLEAYGVDTAAAVEVL 206
>UniRef50_A4IN46 Cluster: 3-hydroxyisobutyrate dehydrogenase-like
protein; n=2; Geobacillus|Rep: 3-hydroxyisobutyrate
dehydrogenase-like protein - Geobacillus
thermodenitrificans (strain NG80-2)
Length = 304
Score = 130 bits (315), Expect = 4e-29
Identities = 71/207 (34%), Positives = 110/207 (53%)
Frame = +3
Query: 183 NVAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGVTPANSIXXXXXXXXXXX 362
NV F+GLG MG MA L+ GF V Y+ + + ++G A +I
Sbjct: 3 NVGFIGLGMMGSRMAKRLLDAGFPVTVYNRTPEKAAILVESGARQAETIAALASEVDVIC 62
Query: 363 SILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAPVS 542
+ L+ V++VY G+ GV++ A++G + +D +T+ P + + A E+G+ + DAPVS
Sbjct: 63 TCLSMPDDVINVYTGEGGVLSAARRGVICLDFTTVGPKTSRFVAGRAGERGVAYLDAPVS 122
Query: 543 GGVMGAQNATLAFMAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMGITG 722
GG GA+ TL M GG + +ER PLL V+G + G+ G+G AK+ N L+ +
Sbjct: 123 GGPEGAEQGTLTIMVGGDQAAWERVRPLLSVLGKTVEYLGESGAGSAAKILNQYLVAVHS 182
Query: 723 MAXAECMXMGIKMGLXPKVLLDVLNNS 803
+A AE M G+ GL L +L S
Sbjct: 183 VAAAEAMVAGVAYGLDAGKLYRLLKES 209
>UniRef50_A0C2T7 Cluster: Chromosome undetermined scaffold_145,
whole genome shotgun sequence; n=2; Paramecium
tetraurelia|Rep: Chromosome undetermined scaffold_145,
whole genome shotgun sequence - Paramecium tetraurelia
Length = 299
Score = 130 bits (315), Expect = 4e-29
Identities = 75/212 (35%), Positives = 114/212 (53%)
Frame = +3
Query: 186 VAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGVTPANSIXXXXXXXXXXXS 365
+ F+GLGNMG MA NL K V YD S + + + P N + +
Sbjct: 14 IGFIGLGNMGIGMAHNLAKTR-VVYAYDVSPAWQSNIESSNIKPVNQVADVAANADTIIT 72
Query: 366 ILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAPVSG 545
+L ++K+V V + +KK +LIDSSTI P ++ +A + + DAPVSG
Sbjct: 73 MLPNDKIVKSV---AQEIFKKSKK--ILIDSSTISPYTSYELAKMAQDTQNIYADAPVSG 127
Query: 546 GVMGAQNATLAFMAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMGITGM 725
V A+ T+ FM G KE +E+ P+LK MG F+CG+IG GQ+AK+ NM + I +
Sbjct: 128 SVSEAKLGTITFMVGAEKELYEKISPILKEMGKNIFNCGKIGEGQIAKMCGNMALAIQMI 187
Query: 726 AXAECMXMGIKMGLXPKVLLDVLNNSSXRSWS 821
+ E + +G MG+ P +L +++ SS R W+
Sbjct: 188 SVCEALALGKNMGMDPAMLSSIMSVSSSRCWT 219
>UniRef50_Q97XZ7 Cluster: Oxidoreductase; n=6; Thermoprotei|Rep:
Oxidoreductase - Sulfolobus solfataricus
Length = 289
Score = 130 bits (314), Expect = 5e-29
Identities = 71/217 (32%), Positives = 113/217 (52%)
Frame = +3
Query: 186 VAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGVTPANSIXXXXXXXXXXXS 365
V F+GLG MG MA+NL+K G+ + Y+ + + K G A+S S
Sbjct: 3 VGFIGLGIMGFPMASNLLKAGYDLTVYNRTIEKAEKLGKMGAKVAHSPKEVAEVSEIVIS 62
Query: 366 ILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAPVSG 545
++T V +V G++GVV K+G + +D ST P K++ E G+ F DAPV+G
Sbjct: 63 MVTDAPDVEEVLFGENGVVKSNKRGLIFVDMSTNSPEFAKKVTKRLSEYGMEFLDAPVTG 122
Query: 546 GVMGAQNATLAFMAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMGITGM 725
G GA+ TL M GG+++ F+R P+ K MG H G +GSGQ KL N +++ + +
Sbjct: 123 GDKGAREGTLTIMVGGKEDVFKRVEPIFKAMGKNIIHVGDVGSGQALKLCNQVVVALNMV 182
Query: 726 AXAECMXMGIKMGLXPKVLLDVLNNSSXRSWSTXXVL 836
+ E + + +G+ L VL+ + S++ L
Sbjct: 183 SVVEGLLLARSLGIDDDKLFSVLSTGAANSFTVQYYL 219
>UniRef50_Q11FC5 Cluster: 6-phosphogluconate dehydrogenase,
NAD-binding; n=2; Rhizobiales|Rep: 6-phosphogluconate
dehydrogenase, NAD-binding - Mesorhizobium sp. (strain
BNC1)
Length = 292
Score = 128 bits (309), Expect = 2e-28
Identities = 75/211 (35%), Positives = 107/211 (50%)
Frame = +3
Query: 186 VAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGVTPANSIXXXXXXXXXXXS 365
+AF+G G MG M ANL K GF ++ YD S AL +GVT A+S+ +
Sbjct: 4 LAFIGAGVMGRPMIANLRKAGFALKAYDRSPAALENLRSDGVTVADSLAAAVAGADVVVT 63
Query: 366 ILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAPVSG 545
+L V V LG+DG+ G+L+ID STI + + I +G+ DAPVSG
Sbjct: 64 MLPDTPHVQSVLLGEDGIGTLLPTGTLVIDMSTISASGIRAIGQDLASRGVDLVDAPVSG 123
Query: 546 GVMGAQNATLAFMAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMGITGM 725
GV GA L+ M GG E F ++ P+L+ MG H G +G GQV K+ N +++G+
Sbjct: 124 GVRGAIAGELSIMCGGSPEAFAKARPVLEGMGTTIIHAGDLGMGQVFKMCNQLMVGVHIQ 183
Query: 726 AXAECMXMGIKMGLXPKVLLDVLNNSSXRSW 818
A E + G +L + L + SW
Sbjct: 184 AMCEAFALCRAQGGDLNLLRETLMGGAAGSW 214
>UniRef50_A3RRS1 Cluster: 2-hydroxy-3-oxopropionate reductase; n=11;
Betaproteobacteria|Rep: 2-hydroxy-3-oxopropionate
reductase - Ralstonia solanacearum UW551
Length = 298
Score = 128 bits (309), Expect = 2e-28
Identities = 80/204 (39%), Positives = 103/204 (50%), Gaps = 4/204 (1%)
Frame = +3
Query: 186 VAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGVTPANSIXXXXXXXXXXXS 365
+AF+GLGNMG M +LV G VR Y +A + A G P +S +
Sbjct: 4 IAFIGLGNMGSPMVGHLVAAGHAVRAYVRRPEAADRARALGAEPCDSPADAARDAEVVFT 63
Query: 366 ILTSNKVVLDVYLGKDGVVAHAKKG----SLLIDSSTIDPNVPKQIFPIALEKGLGFTDA 533
+TS V V LG DGV+ A +G ++ ID STI ++I GL F DA
Sbjct: 64 NVTSTADVEAVLLGPDGVIHGAPRGKPGSAVCIDHSTISAVATRRIAAELETAGLDFLDA 123
Query: 534 PVSGGVMGAQNATLAFMAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMG 713
PVSGG MGAQ ATL+ M GG+ E ER PLL+++G H G G+GQVAK N ++
Sbjct: 124 PVSGGTMGAQKATLSIMVGGKAEVLERVRPLLQLLGTTITHIGDHGAGQVAKACNQIVQV 183
Query: 714 ITGMAXAECMXMGIKMGLXPKVLL 785
I AE M G P +L
Sbjct: 184 INIQGIAEAMLFARAQGTDPSRVL 207
>UniRef50_Q92D17 Cluster: Lin1004 protein; n=10; Bacilli|Rep:
Lin1004 protein - Listeria innocua
Length = 286
Score = 126 bits (305), Expect = 6e-28
Identities = 69/214 (32%), Positives = 111/214 (51%)
Frame = +3
Query: 180 KNVAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGVTPANSIXXXXXXXXXX 359
+ + F+G G MG MA +L++ G+ V Y +K+ A G +
Sbjct: 2 EKIGFVGTGVMGSSMAKHLLEAGYEVHIYTRTKEKAEALLSQGALWESDPGSLGAKVDIL 61
Query: 360 XSILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAPV 539
S++ K V +YLG++G + + K GS+ ID +T P + K+I EKG+G DAPV
Sbjct: 62 ISMVGYPKDVEQLYLGENGFLDNLKAGSVAIDMTTSSPALAKKIAEAGHEKGIGVLDAPV 121
Query: 540 SGGVMGAQNATLAFMAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMGIT 719
SGG +GA+N TLA M GG ++ F + P+ +++G+ G GSGQ K+ N + +
Sbjct: 122 SGGDIGAKNGTLAIMVGGAEDVFLKVKPIFEILGSSVILQGDAGSGQHTKMVNQIAIASN 181
Query: 720 GMAXAECMXMGIKMGLXPKVLLDVLNNSSXRSWS 821
+ E + + GL P +LD ++ + SWS
Sbjct: 182 MIGVTEAIIYAERAGLNPSRVLDSISGGAAGSWS 215
>UniRef50_A3SJ77 Cluster: Probable oxidoreductase; n=1; Roseovarius
nubinhibens ISM|Rep: Probable oxidoreductase -
Roseovarius nubinhibens ISM
Length = 320
Score = 125 bits (302), Expect = 1e-27
Identities = 76/209 (36%), Positives = 101/209 (48%)
Frame = +3
Query: 180 KNVAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGVTPANSIXXXXXXXXXX 359
+ VAF+GLG MG MAA LV G VRG D L A + G PA S+
Sbjct: 12 RRVAFIGLGTMGSGMAARLVAAGHEVRGVDIDSARLAAFEEVGGLPAASVAEACDGAEII 71
Query: 360 XSILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAPV 539
+IL + V + LG G+ A G+L+I+ STI P I KGL DAPV
Sbjct: 72 MTILPRDTHVRQICLGAGGIADSAAPGTLVIEMSTISPEASLDIHDALTSKGLRVLDAPV 131
Query: 540 SGGVMGAQNATLAFMAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMGIT 719
AQN L MAGGR EDF + P+ + K H G GSG K+ NN + ++
Sbjct: 132 GRTPKDAQNGALLIMAGGRAEDFADAAPVFAPLADKIVHLGPKGSGIRMKIANNYMSMVS 191
Query: 720 GMAXAECMXMGIKMGLXPKVLLDVLNNSS 806
+ AE + M K G+ ++VL N++
Sbjct: 192 MVLTAETLAMARKAGIDTDAAVEVLQNTT 220
>UniRef50_Q89UN2 Cluster: Bll1384 protein; n=9; Bacteria|Rep:
Bll1384 protein - Bradyrhizobium japonicum
Length = 356
Score = 125 bits (301), Expect = 2e-27
Identities = 73/222 (32%), Positives = 113/222 (50%)
Frame = +3
Query: 141 YTAARRAYSSNTDKNVAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGVTPA 320
++ +R ++ ++ F+GLGNMG MA L++ G + +D K+ ++ G TPA
Sbjct: 42 FSRQQRIINTRNTMDIGFIGLGNMGFPMARRLIEAGNRLVVFDTRKEVVDKLVARGATPA 101
Query: 321 NSIXXXXXXXXXXXSILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPI 500
S + L S + L+V G +GV+ + ID ST+ + +I +
Sbjct: 102 TSPKDVADQVETVMASLPSLQASLEVATGTNGVI-EGSRVKRFIDLSTVGSTMASKIHGL 160
Query: 501 ALEKGLGFTDAPVSGGVMGAQNATLAFMAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQ 680
++ + D PVSGGV GA+ TLA M G K +FE P L V+G F + G+ Q
Sbjct: 161 LAKRDIVQIDCPVSGGVGGAEKGTLAVMVSGPKAEFELLKPALDVIGKVFFIGEKPGAAQ 220
Query: 681 VAKLTNNMLMGITGMAXAECMXMGIKMGLXPKVLLDVLNNSS 806
KL NN L +A +E + MG+K GL P V++DV+N S
Sbjct: 221 TMKLANNFLSATAIVATSEAVVMGVKAGLDPAVMIDVINAGS 262
>UniRef50_A6SW62 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=1;
Janthinobacterium sp. Marseille|Rep:
3-hydroxyisobutyrate dehydrogenase - Janthinobacterium
sp. (strain Marseille) (Minibacterium massiliensis)
Length = 298
Score = 124 bits (300), Expect = 2e-27
Identities = 74/207 (35%), Positives = 103/207 (49%), Gaps = 1/207 (0%)
Frame = +3
Query: 180 KNVAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNA-AAKNGVTPANSIXXXXXXXXX 356
+N+ F+G+GNMG MA L +KGF++ YD NA A ++G A S
Sbjct: 5 RNIGFIGIGNMGAPMAGQLARKGFSLTVYDTHATTANAFAQEHGARVARSAAEVGIGADA 64
Query: 357 XXSILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAP 536
+L S++VV V L DG+ GS+ ID T P V + I G+G+ DAP
Sbjct: 65 VIFMLPSDQVVRQV-LFTDGLATQLAPGSIAIDMGTSAPAVTRSISAELATLGIGYLDAP 123
Query: 537 VSGGVMGAQNATLAFMAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMGI 716
V GGV+ A++A+L M G ER PL MG K + CG IGS V K N +
Sbjct: 124 VMGGVVFAKDASLDIMVSGDDASIERCRPLFDAMGRKLWPCGDIGSAHVLKAMTNYINAC 183
Query: 717 TGMAXAECMXMGIKMGLXPKVLLDVLN 797
+ E M +G K GL KV+ + ++
Sbjct: 184 ALINTLEAMTIGRKFGLDSKVMAEAID 210
>UniRef50_Q183P5 Cluster: 2-hydroxy-3-oxopropionate reductase; n=5;
Bacteria|Rep: 2-hydroxy-3-oxopropionate reductase -
Clostridium difficile (strain 630)
Length = 296
Score = 123 bits (296), Expect = 7e-27
Identities = 69/197 (35%), Positives = 105/197 (53%)
Frame = +3
Query: 186 VAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGVTPANSIXXXXXXXXXXXS 365
+ F+GLG MG MA NL+K G + YD +K A++ G A S+ +
Sbjct: 3 LGFIGLGIMGKPMAKNLLKDGCNLLVYDINKSAVDELISCGAKYA-SVLEMGQECDIVFT 61
Query: 366 ILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAPVSG 545
IL + +V D+ G DG+ K+GS+++D S++ P + GL F D+PVSG
Sbjct: 62 ILPNGTIVQDILFGMDGLAKTLKEGSIVVDMSSVTPTESILCANKLKDMGLEFIDSPVSG 121
Query: 546 GVMGAQNATLAFMAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMGITGM 725
G A + TLAFMAGG++E +++ P +MG+ G GSG V KLTN +++ +T
Sbjct: 122 GEPKAIDGTLAFMAGGKEEIYKKVEPFFNIMGSSSILIGDNGSGSVTKLTNQVIVNLTIA 181
Query: 726 AXAECMXMGIKMGLXPK 776
A +E + K G P+
Sbjct: 182 AVSEAFVLAAKAGADPE 198
>UniRef50_Q930C6 Cluster: Probable; n=8; Alphaproteobacteria|Rep:
Probable - Rhizobium meliloti (Sinorhizobium meliloti)
Length = 295
Score = 122 bits (294), Expect = 1e-26
Identities = 68/194 (35%), Positives = 99/194 (51%)
Frame = +3
Query: 186 VAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGVTPANSIXXXXXXXXXXXS 365
VA +G G MGG + A LV+ G + +DP D + A G A S
Sbjct: 5 VALIGAGAMGGSIGARLVETGNRLTVFDPGPDKVQALVDKGAFAAPSAAEAAAVSDYVIL 64
Query: 366 ILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAPVSG 545
L + +V G GV A A+ G+L+ID S+IDPN KQ+ A EKGL + D+P+SG
Sbjct: 65 SLNAPAIVRQAVFGDAGVAAGAQAGTLIIDMSSIDPNATKQLAADAAEKGLRWVDSPLSG 124
Query: 546 GVMGAQNATLAFMAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMGITGM 725
G A L MAGG +D + + +L+ + + H G +G+GQ KL N +L G+ +
Sbjct: 125 GAPKALIGELTLMAGGTAQDVKDAHAVLRHVASNYTHMGSVGAGQTTKLINQVLCGLGFL 184
Query: 726 AXAECMXMGIKMGL 767
A AE + + G+
Sbjct: 185 AVAEATQLALDAGV 198
>UniRef50_A6LT11 Cluster: 6-phosphogluconate dehydrogenase,
NAD-binding; n=3; Clostridiales|Rep: 6-phosphogluconate
dehydrogenase, NAD-binding - Clostridium beijerinckii
NCIMB 8052
Length = 291
Score = 122 bits (294), Expect = 1e-26
Identities = 67/213 (31%), Positives = 112/213 (52%)
Frame = +3
Query: 180 KNVAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGVTPANSIXXXXXXXXXX 359
K + F+G+G MG M NL+KKG+ V Y +K+ + G + +
Sbjct: 2 KTIGFIGVGVMGKSMVRNLMKKGYEVSIYTRTKEKVLDVINEGAKWCDDVKSCANNRDVI 61
Query: 360 XSILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAPV 539
+I+ K V +VY G++G++ +AKK S +ID +T P + +I+ A ++ + DAPV
Sbjct: 62 ITIVGYPKDVEEVYFGENGILENAKKESCIIDMTTTSPKLSIKIYNEAKKREIYALDAPV 121
Query: 540 SGGVMGAQNATLAFMAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMGIT 719
SGG +GA+NATL+ M GG E FE+ +L +G + G+ G+GQ K+ N + +
Sbjct: 122 SGGDVGAKNATLSIMVGGDLEVFEKHKDVLSALGTNIIYEGKAGNGQHTKMANQIALAGA 181
Query: 720 GMAXAECMXMGIKMGLXPKVLLDVLNNSSXRSW 818
E + +GL + +LD ++ + SW
Sbjct: 182 IAGVCEAITYAKGVGLDVQTMLDSISEGAAGSW 214
>UniRef50_P0ABQ3 Cluster: 2-hydroxy-3-oxopropionate reductase; n=25;
Bacteria|Rep: 2-hydroxy-3-oxopropionate reductase -
Escherichia coli O6
Length = 294
Score = 122 bits (294), Expect = 1e-26
Identities = 66/203 (32%), Positives = 110/203 (54%)
Frame = +3
Query: 186 VAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGVTPANSIXXXXXXXXXXXS 365
V F+GLG MG M+ NL+K G+++ D + +A+ G A++ +
Sbjct: 3 VGFIGLGIMGKPMSKNLLKAGYSLVVADRNPEAIADVIAAGAETASTAKAIAEQCDVIIT 62
Query: 366 ILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAPVSG 545
+L ++ V +V LG++G++ AK G++LID S+I P ++I KG+ DAPVSG
Sbjct: 63 MLPNSPHVKEVALGENGIIEGAKPGTVLIDMSSIAPLASREISEALKAKGIDMLDAPVSG 122
Query: 546 GVMGAQNATLAFMAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMGITGM 725
G A + TL+ M GG K F++ L+K M H G+IG+G V KL N +++ +
Sbjct: 123 GEPKAIDGTLSVMVGGDKAIFDKYYDLMKAMAGSVVHTGEIGAGNVTKLANQVIVALNIA 182
Query: 726 AXAECMXMGIKMGLXPKVLLDVL 794
A +E + + K G+ P ++ +
Sbjct: 183 AMSEALTLATKAGVNPDLVYQAI 205
>UniRef50_Q18X68 Cluster: 6-phosphogluconate dehydrogenase,
NAD-binding; n=2; Desulfitobacterium hafniense|Rep:
6-phosphogluconate dehydrogenase, NAD-binding -
Desulfitobacterium hafniense (strain DCB-2)
Length = 298
Score = 122 bits (293), Expect = 2e-26
Identities = 74/213 (34%), Positives = 112/213 (52%)
Frame = +3
Query: 186 VAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGVTPANSIXXXXXXXXXXXS 365
+ F+GLG MG MA NL+K G + YD + + G A I S
Sbjct: 3 LGFIGLGQMGKHMALNLLKSGEELIVYDQRPASYPEFEQRGARTAAQIRDVAEADIIFCS 62
Query: 366 ILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAPVSG 545
L +++VV V LG+ G+ + G +++D+STI+ + +I G+ F DAPVSG
Sbjct: 63 -LPNSEVVCQVVLGETGLKKVLRAGQIIVDTSTINYSTTLEIGKQLESVGVEFIDAPVSG 121
Query: 546 GVMGAQNATLAFMAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMGITGM 725
A+ TL M GG++E FE P L+ K + GQ GSGQ+ KL N +L I
Sbjct: 122 MESRAKEGTLTTMCGGKQELFENVKPYLQCFADKILYMGQPGSGQLTKLINQLLFDINVA 181
Query: 726 AXAECMXMGIKMGLXPKVLLDVLNNSSXRSWST 824
A AE + M +K+GL P+ + V+N+ + RS+++
Sbjct: 182 ALAEILPMSVKLGLDPEKVGAVVNSGTGRSYAS 214
>UniRef50_Q12CU4 Cluster: 2-hydroxy-3-oxopropionate reductase; n=17;
Proteobacteria|Rep: 2-hydroxy-3-oxopropionate reductase
- Polaromonas sp. (strain JS666 / ATCC BAA-500)
Length = 298
Score = 122 bits (293), Expect = 2e-26
Identities = 74/195 (37%), Positives = 101/195 (51%)
Frame = +3
Query: 180 KNVAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGVTPANSIXXXXXXXXXX 359
+ + FLG G+MG MA L + G+ ++ ++ + + A G T
Sbjct: 10 RKITFLGTGSMGLPMARRLCEAGYALQVWNRTPARAASLAALGATIHEQARAAARDADIV 69
Query: 360 XSILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAPV 539
S+L + VV DV + GV A K GSL +D ++I P + G+ D PV
Sbjct: 70 VSMLENGAVVQDVLFAQ-GVAAAMKPGSLFLDMASITPREARDHAARLGALGIAHLDTPV 128
Query: 540 SGGVMGAQNATLAFMAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMGIT 719
SGG +GA+ TL MAGG+ DFERSLPLLKV G + H G GSGQ+ KL N M++GIT
Sbjct: 129 SGGTVGAEQGTLVIMAGGKPADFERSLPLLKVFG-RATHVGPHGSGQLTKLANQMIVGIT 187
Query: 720 GMAXAECMXMGIKMG 764
A AE + K G
Sbjct: 188 IGAVAEALLFATKGG 202
>UniRef50_A6GTB5 Cluster: 6-phosphogluconate dehydrogenase,
NAD-binding protein; n=1; Limnobacter sp. MED105|Rep:
6-phosphogluconate dehydrogenase, NAD-binding protein -
Limnobacter sp. MED105
Length = 299
Score = 121 bits (292), Expect = 2e-26
Identities = 71/207 (34%), Positives = 101/207 (48%)
Frame = +3
Query: 174 TDKNVAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGVTPANSIXXXXXXXX 353
T + F+GLGNMG MA +L K G+TV + + A A + P SI
Sbjct: 7 TLNTIGFIGLGNMGAAMAGHLCKAGYTVLAWARNASTFEALADIPLVPQPSIEALCASTR 66
Query: 354 XXXSILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDA 533
+T+ V + G+ HA+ GS+++D STID I +G+ + D
Sbjct: 67 LVALNVTNTADVQSLLFRDGGIAQHAQPGSIIVDFSTIDAAAVADIARQLKSRGVDYIDC 126
Query: 534 PVSGGVMGAQNATLAFMAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMG 713
PVSGG GA+ ATL+ MAGG F R P+LK +G H G G+GQ K N M +
Sbjct: 127 PVSGGAAGARAATLSMMAGGDLAAFNRIEPMLKHLGKTIRHVGPSGAGQAIKAANQMALC 186
Query: 714 ITGMAXAECMXMGIKMGLXPKVLLDVL 794
I + AE M ++ G V+L++L
Sbjct: 187 IQLVGIAEAMNYALEQGAELSVVLELL 213
>UniRef50_A3K497 Cluster: Probable 6-phosphogluconate dehydrogenase
protein; n=1; Sagittula stellata E-37|Rep: Probable
6-phosphogluconate dehydrogenase protein - Sagittula
stellata E-37
Length = 298
Score = 121 bits (292), Expect = 2e-26
Identities = 75/227 (33%), Positives = 119/227 (52%), Gaps = 3/227 (1%)
Frame = +3
Query: 177 DKNVAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGVTPANSIXXXXXXXXX 356
DK + F+GLGNMG MA +LV+ GF V YD + A A+ +
Sbjct: 3 DKLIGFIGLGNMGTAMARHLVRGGFEVLAYDIDAEKRAAFAEETGMRNPATVAELAEATV 62
Query: 357 XXSILTSNKVVLDVYL--GKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTD 530
++L + +V V G+ G++ + G+L+ID+++ P +++ + +G D
Sbjct: 63 LLTMLPNGAIVRKVLDEGGEAGLLGQMQPGTLMIDTTSSPPEATRELAAVLNARGCHLVD 122
Query: 531 APVSGGVMGAQNATLAFMAGGRKED-FERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNML 707
APVSG GA+ A L FM G + ER+ +L +G + FH G +G+G K NN +
Sbjct: 123 APVSGARAGAEAADLVFMIGCDDDAVLERTRAVLSCLGNRLFHLGPVGAGHAMKALNNYV 182
Query: 708 MGITGMAXAECMXMGIKMGLXPKVLLDVLNNSSXRSWSTXXVLSXPR 848
+A AE M +G ++GL P ++DVLN S+ R++ST +S PR
Sbjct: 183 SAAGYVAAAEAMIIGTEVGLDPAQIVDVLNVSTGRNFSTE--VSMPR 227
>UniRef50_Q01ZG6 Cluster: 2-hydroxy-3-oxopropionate reductase; n=6;
Bacteria|Rep: 2-hydroxy-3-oxopropionate reductase -
Solibacter usitatus (strain Ellin6076)
Length = 298
Score = 121 bits (291), Expect = 3e-26
Identities = 69/204 (33%), Positives = 105/204 (51%)
Frame = +3
Query: 183 NVAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGVTPANSIXXXXXXXXXXX 362
++ F+GLG MG M+ NL+K G+++ YD + + G S
Sbjct: 3 DIGFIGLGIMGKPMSRNLMKAGYSLVVYDIFPGPVAELKEAGAGAGASCAATAAAAPIVI 62
Query: 363 SILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAPVS 542
++L V LG GV+ AK G++++D S+I P V +++ KG+ F DAPVS
Sbjct: 63 TMLPDGPEVETAVLGPGGVLEGAKAGTVVVDMSSISPMVSQKVAAACAAKGVEFLDAPVS 122
Query: 543 GGVMGAQNATLAFMAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMGITG 722
GG A + TLA M GG+ E FER P+L MGA G +G+G V KL N +++
Sbjct: 123 GGEPKAIDGTLAIMVGGKPEVFERVQPVLAKMGASVTLTGAVGAGNVTKLANQIMVACNI 182
Query: 723 MAXAECMXMGIKMGLXPKVLLDVL 794
A E + + K GL P+V+ + +
Sbjct: 183 AAMGEALVLATKAGLDPEVVFNAV 206
>UniRef50_Q1GJB9 Cluster: 6-phosphogluconate dehydrogenase
NAD-binding; n=1; Silicibacter sp. TM1040|Rep:
6-phosphogluconate dehydrogenase NAD-binding -
Silicibacter sp. (strain TM1040)
Length = 304
Score = 120 bits (290), Expect = 4e-26
Identities = 75/215 (34%), Positives = 112/215 (52%), Gaps = 2/215 (0%)
Frame = +3
Query: 177 DKNVAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGV-TPANSIXXXXXXXX 353
+K +GLG MG MA +L+K GF V GYDP++ A AA GV A++
Sbjct: 6 NKRAGVIGLGAMGLGMARSLLKAGFAVSGYDPAETARENAAAAGVWLTADTDAVFADCDV 65
Query: 354 XXXSILTSNKVVLDVYLGKD-GVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTD 530
S+ T+ V+ V + G +A +++D+ST + + + G GF D
Sbjct: 66 IVLSLPTAQHVLAVVQAAQAAGHLAQTGAARVIVDTSTSEAATSRTLAAELSALGHGFLD 125
Query: 531 APVSGGVMGAQNATLAFMAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLM 710
APVSGG GA + L+ M GG + E + P L+ M AK H G G+G VAKL NNML+
Sbjct: 126 APVSGGPAGAASGQLSVMLGGETQWLEAARPALEAMAAKILHVGPSGAGNVAKLVNNMLV 185
Query: 711 GITGMAXAECMXMGIKMGLXPKVLLDVLNNSSXRS 815
+ E + +G G+ K +L+V+N+++ RS
Sbjct: 186 ANHMVTTLEALRLGEAAGVAAKEMLEVVNSATGRS 220
>UniRef50_A0G5G5 Cluster: 6-phosphogluconate dehydrogenase,
NAD-binding; n=3; Proteobacteria|Rep: 6-phosphogluconate
dehydrogenase, NAD-binding - Burkholderia phymatum
STM815
Length = 306
Score = 120 bits (288), Expect = 7e-26
Identities = 73/215 (33%), Positives = 107/215 (49%)
Frame = +3
Query: 180 KNVAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGVTPANSIXXXXXXXXXX 359
+ + F+GLGNMGG M LV G +V GYD + + + AA G A+SI
Sbjct: 4 ERIGFIGLGNMGGRMTRRLVDAGISVLGYDTAPERVKAA---GAQAASSIADVMKFADVV 60
Query: 360 XSILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAPV 539
L +KVV V G GV+AH + +++D ST + ++ + G+ + DA +
Sbjct: 61 MMSLPDSKVVEAVVEGDGGVLAHCRARQIVVDLSTAAASSTIRLARRFTQSGVQYVDAGI 120
Query: 540 SGGVMGAQNATLAFMAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMGIT 719
SGG A+ L M GG + + +K H G+ G+G KL NN L ++
Sbjct: 121 SGGAAAAEKGALTLMVGGDASAVDALKWAFAPISSKVAHMGESGAGHTTKLLNNFLNAVS 180
Query: 720 GMAXAECMXMGIKMGLXPKVLLDVLNNSSXRSWST 824
A AE M G K GL +LLDVLN+SS +++T
Sbjct: 181 LSASAEVMVAGKKAGLDLHLLLDVLNSSSGVNFAT 215
>UniRef50_A0N0V2 Cluster: BtdhL; n=1; Azoarcus anaerobius|Rep: BtdhL
- Azoarcus anaerobius
Length = 303
Score = 119 bits (287), Expect = 9e-26
Identities = 66/209 (31%), Positives = 106/209 (50%)
Frame = +3
Query: 177 DKNVAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGVTPANSIXXXXXXXXX 356
D V ++GLG MG MAANL+ G + Y+ S +A + G A S+
Sbjct: 6 DTRVGWIGLGKMGTPMAANLLAAGHAITVYNRSAARADALVEKGAALAPSVAALARDCAI 65
Query: 357 XXSILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAP 536
S+++ + + + L GV A G + ID ST+ P + ++I A KG+ + AP
Sbjct: 66 VISMVSDDAALQGITLDAGGVFEAATPGMVFIDMSTVSPALSERIAAAASAKGIHYLRAP 125
Query: 537 VSGGVMGAQNATLAFMAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMGI 716
VSG A L +A G K+ +ER LPLL+ MG K ++ G + K+ NM++G+
Sbjct: 126 VSGSTTTAAAGALTILASGPKDAYERCLPLLQAMGKKLYYLGPAEQARYLKVAINMMLGV 185
Query: 717 TGMAXAECMXMGIKMGLXPKVLLDVLNNS 803
T E + +G + G+ +++V+NNS
Sbjct: 186 TAGMLGEALALGERGGVEWAQMIEVINNS 214
>UniRef50_A6P2M7 Cluster: Putative uncharacterized protein; n=2;
Bacteria|Rep: Putative uncharacterized protein -
Bacteroides capillosus ATCC 29799
Length = 321
Score = 119 bits (286), Expect = 1e-25
Identities = 68/211 (32%), Positives = 108/211 (51%)
Frame = +3
Query: 186 VAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGVTPANSIXXXXXXXXXXXS 365
+AF+G+G MG M NL+K G+++ Y +K G A+++ S
Sbjct: 38 IAFIGVGIMGKSMVRNLMKAGYSLTIYSRTKAKCEDVIAEGAVWADTVADCVRDAEAVFS 97
Query: 366 ILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAPVSG 545
I+ K V +VY G G++++A+ G+L++D +T P + ++I+ KGL DAPV+G
Sbjct: 98 IVGYPKDVEEVYFGDGGIISNAQPGALIVDMTTSSPALAERIWEAGKAKGLRPLDAPVTG 157
Query: 546 GVMGAQNATLAFMAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMGITGM 725
G GA+ TL+ + GG K DF+ LPL + MG H G G+GQ AKL N + +
Sbjct: 158 GDTGAKAGTLSILVGGDKVDFDACLPLFQAMGKIIVHMGSAGAGQHAKLANQIAIAGALS 217
Query: 726 AXAECMXMGIKMGLXPKVLLDVLNNSSXRSW 818
E + GL LL ++ + S+
Sbjct: 218 GVCEALTYARANGLNLDDLLSAISAGAAGSF 248
>UniRef50_Q1QWQ5 Cluster: 6-phosphogluconate dehydrogenase,
NAD-binding; n=4; Proteobacteria|Rep: 6-phosphogluconate
dehydrogenase, NAD-binding - Chromohalobacter salexigens
(strain DSM 3043 / ATCC BAA-138 / NCIMB13768)
Length = 315
Score = 118 bits (285), Expect = 2e-25
Identities = 72/217 (33%), Positives = 107/217 (49%)
Frame = +3
Query: 144 TAARRAYSSNTDKNVAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGVTPAN 323
T AR + +G G MG MA L + G+ VR ++ S D A +G+ A+
Sbjct: 13 TTAREDRDMQDTTTIGVIGTGLMGAPMARRLAEAGYAVRAWNRSNDKARALTAHGIDIAD 72
Query: 324 SIXXXXXXXXXXXSILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIA 503
S +L+S V D+ LG +GV+AH + L+ S+I + ++ A
Sbjct: 73 S-PRDAAGADIVVVMLSSGPVCDDILLGPEGVIAHMAPHATLVVMSSIPVDTAQRQAQAA 131
Query: 504 LEKGLGFTDAPVSGGVMGAQNATLAFMAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQV 683
+G+G+ DAPVSGG GA + TLA M GG FER PL +G + H G GSGQ+
Sbjct: 132 EARGIGYLDAPVSGGERGAIDGTLAIMVGGDPATFERHRPLFAPLG-RAVHVGPAGSGQL 190
Query: 684 AKLTNNMLMGITGMAXAECMXMGIKMGLXPKVLLDVL 794
AKL N ++ T AE + + + G P+ + + L
Sbjct: 191 AKLANQSIVANTIATVAEALLLAERGGADPRKVREAL 227
>UniRef50_A2U9T6 Cluster: 6-phosphogluconate dehydrogenase,
NAD-binding; n=2; Bacillaceae|Rep: 6-phosphogluconate
dehydrogenase, NAD-binding - Bacillus coagulans 36D1
Length = 294
Score = 118 bits (285), Expect = 2e-25
Identities = 67/207 (32%), Positives = 109/207 (52%)
Frame = +3
Query: 186 VAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGVTPANSIXXXXXXXXXXXS 365
+ ++GLG+MG MA L+ F + Y+ + A+ G + +
Sbjct: 8 IGWIGLGHMGSPMARRLLDAHFDLFVYNRTIKKTEKLAEAGAAVCKTPKDIAENADVIVT 67
Query: 366 ILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAPVSG 545
+LT+ V +V G+DGV+A KG ++D ST+ P+ + EK F DAPVSG
Sbjct: 68 MLTNAAAVENVLQGEDGVLAGLTKGKTVVDMSTVSPSDSIRFAKWVEEKRGHFIDAPVSG 127
Query: 546 GVMGAQNATLAFMAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMGITGM 725
V A+ L +AGGRKE+ + P+ +V+G H G+ G G AKL+ N+L+G+T
Sbjct: 128 SVQPAKEGNLVILAGGRKEEIDAVRPMFEVLGKTIIHFGENGKGSAAKLSINLLLGLTIE 187
Query: 726 AXAECMXMGIKMGLXPKVLLDVLNNSS 806
+E + G K+GL K L+++++ S+
Sbjct: 188 GASEAILFGEKLGLEKKDLIEMISASA 214
>UniRef50_Q5L168 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=15;
Bacteria|Rep: 3-hydroxyisobutyrate dehydrogenase -
Geobacillus kaustophilus
Length = 288
Score = 118 bits (284), Expect = 2e-25
Identities = 63/214 (29%), Positives = 108/214 (50%)
Frame = +3
Query: 180 KNVAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGVTPANSIXXXXXXXXXX 359
K + F+GLG MG MA +L+K G+ + Y +K+ + G ++
Sbjct: 2 KTIGFIGLGVMGKSMARHLLKAGYPLLAYTRTKEKAEDLLQEGAVWKETVADLAREADVV 61
Query: 360 XSILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAPV 539
+++ + V VY G+ G++ +A+ G+ +ID +T P + + I+ A +KG+ DAPV
Sbjct: 62 MTMVGDPRDVEQVYFGEGGILENARPGTYVIDMTTSTPTLAQSIYEAAKQKGIHALDAPV 121
Query: 540 SGGVMGAQNATLAFMAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMGIT 719
SGG +GA+ TL M GG ++ F P+L+ +G G G+GQ K+ N + +
Sbjct: 122 SGGDIGAREGTLTIMVGGDEDVFLACKPILERLGTNIVRQGGAGAGQHTKMCNQIAIATN 181
Query: 720 GMAXAECMXMGIKMGLXPKVLLDVLNNSSXRSWS 821
+ E M + GL P +L+ + + SWS
Sbjct: 182 MIGVCEAMAYAKRAGLDPFKVLESIAKGAAGSWS 215
>UniRef50_Q03UI4 Cluster: 3-hydroxyisobutyrate dehydrogenase related
enzyme; n=2; Lactobacillales|Rep: 3-hydroxyisobutyrate
dehydrogenase related enzyme - Leuconostoc mesenteroides
subsp. mesenteroides (strain ATCC 8293 /NCDO 523)
Length = 287
Score = 117 bits (282), Expect = 4e-25
Identities = 66/213 (30%), Positives = 108/213 (50%)
Frame = +3
Query: 183 NVAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGVTPANSIXXXXXXXXXXX 362
N+ F+G G MG + NL++ G+ V ++ + N NG ++
Sbjct: 2 NIGFIGTGVMGTGIINNLLQAGYEVSVFNRTHSKANTVLNNGAIWRDTPAKVAQYSDITF 61
Query: 363 SILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAPVS 542
+++ K V +V+ +DGV A AK+GS+L+D +T P + +Q+ + G DAPVS
Sbjct: 62 TMVGYPKDVEEVWTSEDGVFAGAKEGSILVDMTTSTPRLAEQLAQTGADLGFKVLDAPVS 121
Query: 543 GGVMGAQNATLAFMAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMGITG 722
GG +GA+N TLA M GG ++ + P+L V+G + G G GQ K++NN+ + T
Sbjct: 122 GGDIGAKNGTLAIMVGGEQQVLDEIKPVLSVIGQQIVFAGSAGKGQHMKMSNNIGVAATV 181
Query: 723 MAXAECMXMGIKMGLXPKVLLDVLNNSSXRSWS 821
+ AE + GL + +V + SWS
Sbjct: 182 ITMAESLVYAKAAGLDLESAYNVWRKGAAGSWS 214
>UniRef50_Q01QM2 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=1;
Solibacter usitatus Ellin6076|Rep: 3-hydroxyisobutyrate
dehydrogenase - Solibacter usitatus (strain Ellin6076)
Length = 298
Score = 117 bits (281), Expect = 5e-25
Identities = 72/213 (33%), Positives = 109/213 (51%), Gaps = 2/213 (0%)
Frame = +3
Query: 183 NVAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAA--KNGVTPANSIXXXXXXXXX 356
N+ FLGLG MG MA NL++ G V + + D A + GV A
Sbjct: 3 NLGFLGLGLMGYPMARNLLRAGHNVAVWSHTSDKARKLADEEKGVFCATPRDVGAGADVV 62
Query: 357 XXSILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAP 536
+ + +V LG G++ + G++++D STI ++I K + F DAP
Sbjct: 63 FLCV-GDTAMAREVILGGQGLIQGLRAGAVVVDCSTIAVADSREIGAALKAKSVDFLDAP 121
Query: 537 VSGGVMGAQNATLAFMAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMGI 716
V+G GA++ L FM GG + F + PLL MG K + CG G G AKLT N+++
Sbjct: 122 VTGSTPGAESGNLTFMIGGDEAVFSKIRPLLDPMGKKIYFCGGAGMGLQAKLTQNLVLSN 181
Query: 717 TGMAXAECMXMGIKMGLXPKVLLDVLNNSSXRS 815
MA E M + K G+ PK++L++L+NS+ +S
Sbjct: 182 ILMAFNEGMVLATKGGMDPKLMLEILDNSAAKS 214
>UniRef50_A0LMG6 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=9;
cellular organisms|Rep: 3-hydroxyisobutyrate
dehydrogenase - Syntrophobacter fumaroxidans (strain DSM
10017 / MPOB)
Length = 309
Score = 117 bits (281), Expect = 5e-25
Identities = 62/212 (29%), Positives = 115/212 (54%)
Frame = +3
Query: 186 VAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGVTPANSIXXXXXXXXXXXS 365
+ ++G G MG M ++++KG+ ++ ++ ++G A+S +
Sbjct: 16 IGWIGTGVMGLSMCGHVMRKGYATSVHNRTRHKAAPLVESGAGWADSPRQVAEQSDVVFT 75
Query: 366 ILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAPVSG 545
+L + V +VY G++G++ A+ G +L+D +T +P++ ++I A E+G DAPVSG
Sbjct: 76 MLGFPQDVREVYFGRNGLLQAARPGIILVDMTTTEPSLAREIHQAAGEQGAFAVDAPVSG 135
Query: 546 GVMGAQNATLAFMAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMGITGM 725
G +GA+NA L+ M GG +E + P+L+ MG + G GSGQ AK+ N +++ T +
Sbjct: 136 GDVGARNAALSIMLGGDREVVDAIRPILEAMGKNLVYLGPAGSGQHAKVCNQIVITGTMI 195
Query: 726 AXAECMXMGIKMGLXPKVLLDVLNNSSXRSWS 821
E + G K GL +L + + + + W+
Sbjct: 196 GVCESLMYGFKAGLDLPTMLSSIKDGAAKCWT 227
>UniRef50_Q2JEV5 Cluster: 6-phosphogluconate dehydrogenase,
NAD-binding; n=6; Bacteria|Rep: 6-phosphogluconate
dehydrogenase, NAD-binding - Frankia sp. (strain CcI3)
Length = 302
Score = 116 bits (280), Expect = 6e-25
Identities = 69/212 (32%), Positives = 106/212 (50%), Gaps = 1/212 (0%)
Frame = +3
Query: 186 VAFLGLGNMGGFMAANLVKKGFTVRGYD-PSKDALNAAAKNGVTPANSIXXXXXXXXXXX 362
VAF+GLG MG MA +LV+ GF+ ++ + A A ++ A S
Sbjct: 3 VAFVGLGTMGFPMAGHLVRAGFSTTAFNRTAATAARWAEEHSGRIAPSPAAAATEVDVVC 62
Query: 363 SILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAPVS 542
+ ++ V +V LG DGV+ + G++++D +T + ++I E G+GF DAPVS
Sbjct: 63 LCVGADDDVREVVLGADGVLGALRPGAIIVDHTTTSAELAEEIAARTAEVGVGFVDAPVS 122
Query: 543 GGVMGAQNATLAFMAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMGITG 722
GG GA L+ M GG E ER+ P+L GA G +GSGQ+ K+ N +L+
Sbjct: 123 GGEAGAMAGRLSIMCGGDPETIERARPVLAAYGATITRIGPVGSGQLTKMVNQILVAGAV 182
Query: 723 MAXAECMXMGIKMGLXPKVLLDVLNNSSXRSW 818
AE + I GL ++L + + SW
Sbjct: 183 EGAAEAINFAIAAGLDTDLVLSAVAGGAANSW 214
>UniRef50_Q0S5S3 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=1;
Rhodococcus sp. RHA1|Rep: 3-hydroxyisobutyrate
dehydrogenase - Rhodococcus sp. (strain RHA1)
Length = 299
Score = 116 bits (280), Expect = 6e-25
Identities = 72/210 (34%), Positives = 103/210 (49%)
Frame = +3
Query: 186 VAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGVTPANSIXXXXXXXXXXXS 365
V F+GLGN+GG + A+LVK G V YD + A++AA G S
Sbjct: 5 VGFVGLGNIGGRVVAHLVKAGHDVAVYDLNTAAVDAAVALGARSVASPGEAARKAEALFL 64
Query: 366 ILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAPVSG 545
L + +V V V+ +G +++D STIDP+ +++ A G F DAPVSG
Sbjct: 65 SLPTPAIVEGVVAD---VLQQGNQGLVIVDHSTIDPDTTRRLAQDAQVAGACFLDAPVSG 121
Query: 546 GVMGAQNATLAFMAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMGITGM 725
GV GA+ TLA M GG + ++ +PL++ FH G GSGQ KL NN + +
Sbjct: 122 GVQGAEAGTLAVMLGGDEASVKKVIPLIETYAGNIFHVGPSGSGQAIKLANNQITAANIV 181
Query: 726 AXAECMXMGIKMGLXPKVLLDVLNNSSXRS 815
A E + + G+ + VL SS S
Sbjct: 182 ALGEGLSSAVAAGVDLDTAVAVLTKSSANS 211
>UniRef50_Q89R44 Cluster: Oxidoreductase; n=23; Bacteria|Rep:
Oxidoreductase - Bradyrhizobium japonicum
Length = 305
Score = 116 bits (278), Expect = 1e-24
Identities = 67/219 (30%), Positives = 106/219 (48%), Gaps = 1/219 (0%)
Frame = +3
Query: 165 SSNTDKNVAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGVTPANSIXXXXX 344
S++ ++ +A +GLG+MG MA +L + G V G D S DA+ K+G A +
Sbjct: 4 STSQNQRIAVVGLGSMGFGMATSLKRAGHAVTGCDVSADAVARFVKDGGAGAKTPAEAAR 63
Query: 345 XXXXXXSILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGF 524
S++ + + GKDGV K S+ + S+T+DP+V +++ G +
Sbjct: 64 GADVVVSVVVNAAQTETILFGKDGVAETMPKDSVFLSSATMDPDVARRLAKQLEATGRHY 123
Query: 525 TDAPVSGGVMGAQNATLAFMAGGRKEDFERSLPLLKVMGAKQFHCGQ-IGSGQVAKLTNN 701
DAP+SGG A L +A G F ++ P L M AK + G G G K+ N
Sbjct: 124 LDAPISGGAQRAAQGELTILASGSPAAFAKARPALDAMAAKLYELGDAAGQGAAFKMINQ 183
Query: 702 MLMGITGMAXAECMXMGIKMGLXPKVLLDVLNNSSXRSW 818
+L G+ A +E M K GL + + +V+ S+ SW
Sbjct: 184 LLAGVHIAAASEAMAFAAKQGLDIRKVYEVITASAGNSW 222
>UniRef50_Q5WBB8 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=1;
Bacillus clausii KSM-K16|Rep: 3-hydroxyisobutyrate
dehydrogenase - Bacillus clausii (strain KSM-K16)
Length = 283
Score = 116 bits (278), Expect = 1e-24
Identities = 71/210 (33%), Positives = 99/210 (47%), Gaps = 1/210 (0%)
Frame = +3
Query: 180 KNVAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGVTPANSIXXXXXXXXXX 359
K V +G G MG MA +L+ G+TV YD K G +
Sbjct: 2 KTVGLIGCGAMGKGMATSLLSAGYTVYIYDDMSKWREPLEKQGACFVENSAAVAKKAKYV 61
Query: 360 XSILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAPV 539
L S +V D GK+GV+ H + G L+D ST D + A KG+ + D PV
Sbjct: 62 LLSLPSPNIVADTVAGKEGVLCHLQTGGFLLDLSTTDVQTTLAMEKAAAAKGIYYLDCPV 121
Query: 540 SGGVMGAQNATLAFMAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLM-GI 716
SGG GA TL M GG K+ + PLL ++G + G G+GQ KL NNML+ GI
Sbjct: 122 SGGPAGADAGTLTIMVGGDKQAYFSVKPLLDILGDTILYVGDSGAGQTVKLCNNMLVAGI 181
Query: 717 TGMAXAECMXMGIKMGLXPKVLLDVLNNSS 806
T + +E M + G+ ++L ++ SS
Sbjct: 182 TTL-LSETMAVASDHGVSRRLLAQIIQQSS 210
>UniRef50_Q4PCH4 Cluster: Putative uncharacterized protein; n=1;
Ustilago maydis|Rep: Putative uncharacterized protein -
Ustilago maydis (Smut fungus)
Length = 366
Score = 115 bits (277), Expect = 1e-24
Identities = 89/283 (31%), Positives = 136/283 (48%), Gaps = 33/283 (11%)
Frame = +3
Query: 126 STQC-LYTAARRAYSSNTDKNVAFLGLGNMGGFMAANLVKK--------GFTVRGYDPSK 278
+T+C L+ RR + K + F+GLG MG MA NL+ K T +D +
Sbjct: 4 TTRCMLHHTIRRCVPHDRSKTIGFIGLGAMGKEMANNLLSKTLASNPDPAVTFVVHDAFE 63
Query: 279 DALNA--AAKNGVTP------ANSIXXXXXXXXXXXSILTSNKVVLDVYLGKDGV----- 419
++ A + P A+S ++L S+ V VY ++G+
Sbjct: 64 QSITRFLTANTSLYPNRNILAASSPAGIAKLSGTIVTMLPSSPQVESVYTHENGILDGLE 123
Query: 420 ------VAHAKKGSLLIDSSTIDPNVPKQ----IFPIALEKGLGFTDAPVSGGVMGAQNA 569
V A+ +L ID +T+DP+V Q I DAPVSGGV+GA A
Sbjct: 124 SFQAAAVDDAQAKTLCIDCTTLDPDVAVQTATAIKNANANGAFDMIDAPVSGGVVGANAA 183
Query: 570 TLAFMAGGRKED-FERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMGITGMAXAECMX 746
TL+FM G F + P L +MG++ HCG+ G+G +AK+ NN+L+GI+ + E M
Sbjct: 184 TLSFMVGSDSSTTFASAEPYLSLMGSRAVHCGKNGNGLIAKIANNLLLGISMLGVTEAML 243
Query: 747 MGIKMGLXPKVLLDVLNNSSXRSWSTXXVLSXPRTGAHRSVQY 875
+G GL P VL ++N S+ + WS+ ++ P GA +Y
Sbjct: 244 LGTAHGLPPAVLAGIINTSTGKCWSSE--VNNPCPGALEGTKY 284
>UniRef50_Q4Q7T9 Cluster: 2-hydroxy-3-oxopropionate reductase,
putative; n=6; Trypanosomatidae|Rep:
2-hydroxy-3-oxopropionate reductase, putative -
Leishmania major
Length = 299
Score = 114 bits (274), Expect = 3e-24
Identities = 66/213 (30%), Positives = 109/213 (51%), Gaps = 1/213 (0%)
Frame = +3
Query: 186 VAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGVTPANSIXXXXXXXXXXXS 365
V ++GLG MG MA N++K GF V ++ + + G T + +
Sbjct: 3 VGYIGLGLMGKPMAVNILKAGFPVSVWNRTASKCDDLVAAGATACATPAELAAASDVVFT 62
Query: 366 ILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFP-IALEKGLGFTDAPVS 542
L+ + V++V G +GV A +G++ +D+STI P+V ++I + EK + DAPVS
Sbjct: 63 NLSDSPDVMEVVFGPNGVAAGICEGAIFVDNSTIKPSVAQEIARRLWKEKKVRALDAPVS 122
Query: 543 GGVMGAQNATLAFMAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMGITG 722
GG +GA+N TL M GG LP+L +G K H G G+GQV K N +++
Sbjct: 123 GGDIGARNGTLTVMVGGDAAALATVLPVLLAVGKKVTHIGDCGAGQVCKAANQIMVAAQM 182
Query: 723 MAXAECMXMGIKMGLXPKVLLDVLNNSSXRSWS 821
+A E + K G+ +++ + + S + W+
Sbjct: 183 VALGEILVFCEKCGVSGPTVIEAIKSGSAQCWT 215
>UniRef50_A1B741 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=3;
Bacteria|Rep: 3-hydroxyisobutyrate dehydrogenase -
Paracoccus denitrificans (strain Pd 1222)
Length = 309
Score = 113 bits (273), Expect = 4e-24
Identities = 71/207 (34%), Positives = 100/207 (48%)
Frame = +3
Query: 186 VAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGVTPANSIXXXXXXXXXXXS 365
+ F+GLG MG MAANL G + D S+ A G T A + +
Sbjct: 3 IGFIGLGKMGRGMAANLQTGGAALVVADLSRTAAEEFTVRGATWAETPADLARDCGIVFT 62
Query: 366 ILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAPVSG 545
L + V + G G+V G++ +D ST +V +QI KG+ F DAPVSG
Sbjct: 63 SLPTPADVRNAGFGPRGLVEGMAPGTVWLDLSTNSVDVVRQIHAELAPKGIHFIDAPVSG 122
Query: 546 GVMGAQNATLAFMAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMGITGM 725
G GA + LA GG +E ++R LP L+ M + + G IG+G +AKL NNM
Sbjct: 123 GPAGAASGQLAIWCGGEREVYDRCLPWLEKMADQPRYIGDIGAGTIAKLVNNMASTAIIS 182
Query: 726 AXAECMXMGIKMGLXPKVLLDVLNNSS 806
AE + MG+K GL P L + + +
Sbjct: 183 VLAEALSMGVKAGLEPGPLWEAIRTGA 209
>UniRef50_Q84VC8 Cluster: Gamma hydroxybutyrate dehydrogenase-like
protein; n=3; Magnoliophyta|Rep: Gamma hydroxybutyrate
dehydrogenase-like protein - Oryza sativa subsp.
japonica (Rice)
Length = 293
Score = 113 bits (273), Expect = 4e-24
Identities = 68/204 (33%), Positives = 99/204 (48%)
Frame = +3
Query: 186 VAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGVTPANSIXXXXXXXXXXXS 365
V FLGLG MG MAANL++ GF V ++ + G + +
Sbjct: 3 VGFLGLGIMGKAMAANLLRHGFRVTVWNRTLSKCQELVALGAAVGETPAAVVAKCRYTIA 62
Query: 366 ILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAPVSG 545
+L+ L V KDGV+ +G +D ST+D +I +KG F +APVSG
Sbjct: 63 MLSDPSAALSVVFDKDGVLEQIGEGKGYVDMSTVDAATSCKISEAIKQKGGAFVEAPVSG 122
Query: 546 GVMGAQNATLAFMAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMGITGM 725
A++ L +A G K ++ +P V+G K F G+IG+G KL NM+MG
Sbjct: 123 SKKPAEDGQLVILAAGDKVLYDDMVPAFDVLGKKSFFLGEIGNGAKMKLVVNMIMGSMMN 182
Query: 726 AXAECMXMGIKMGLXPKVLLDVLN 797
A +E + + GL P+ LLDVL+
Sbjct: 183 ALSEGLSLADNSGLSPQTLLDVLD 206
>UniRef50_A5USN9 Cluster: 6-phosphogluconate dehydrogenase,
NAD-binding; n=2; Roseiflexus|Rep: 6-phosphogluconate
dehydrogenase, NAD-binding - Roseiflexus sp. RS-1
Length = 302
Score = 113 bits (272), Expect = 6e-24
Identities = 68/209 (32%), Positives = 103/209 (49%)
Frame = +3
Query: 180 KNVAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGVTPANSIXXXXXXXXXX 359
+ + F+GLG MG MA L+ GF + ++ ++ A G A +
Sbjct: 2 ERLGFIGLGRMGQVMAGRLLAAGFPLTVHNRTRARAEALLAGGAAWAETPAEVTARSDLV 61
Query: 360 XSILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAPV 539
+ILT + V VY G+DG+++ G L I+ STI + + + ++G DAPV
Sbjct: 62 FTILTDDHAVETVYCGRDGLLSTDASGRLFIEMSTIRTSTILSLAGMVDQRGARLLDAPV 121
Query: 540 SGGVMGAQNATLAFMAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMGIT 719
SG V A+ L + GGR D ER+ P L V+G + H G G+G KL NM M
Sbjct: 122 SGTVAPAREGQLLVLVGGRTSDLERARPALGVLGRRIIHLGGQGAGTTMKLVLNMTMACF 181
Query: 720 GMAXAECMXMGIKMGLXPKVLLDVLNNSS 806
A AE + +G + GL + +LDV +S+
Sbjct: 182 WGALAESLAVGQQFGLNIETMLDVYLDSA 210
>UniRef50_Q94B07 Cluster: Gamma hydroxybutyrate dehydrogenase; n=16;
cellular organisms|Rep: Gamma hydroxybutyrate
dehydrogenase - Arabidopsis thaliana (Mouse-ear cress)
Length = 289
Score = 113 bits (272), Expect = 6e-24
Identities = 68/204 (33%), Positives = 100/204 (49%)
Frame = +3
Query: 186 VAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGVTPANSIXXXXXXXXXXXS 365
V FLGLG MG M+ NL+K GF V ++ + + ++G + S +
Sbjct: 3 VGFLGLGIMGKAMSMNLLKNGFKVTVWNRTLSKCDELVEHGASVCESPAEVIKKCKYTIA 62
Query: 366 ILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAPVSG 545
+L+ L V K GV+ +G ID ST+D +I KG F + PVSG
Sbjct: 63 MLSDPCAALSVVFDKGGVLEQICEGKGYIDMSTVDAETSLKINEAITGKGGRFVEGPVSG 122
Query: 546 GVMGAQNATLAFMAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMGITGM 725
A++ L +A G K FE S+P V+G + F+ GQ+G+G KL NM+MG
Sbjct: 123 SKKPAEDGQLIILAAGDKALFEESIPAFDVLGKRSFYLGQVGNGAKMKLIVNMIMGSMMN 182
Query: 726 AXAECMXMGIKMGLXPKVLLDVLN 797
A +E + + K GL LLD+L+
Sbjct: 183 AFSEGLVLADKSGLSSDTLLDILD 206
>UniRef50_Q4KH51 Cluster: 3-hydroxyisobutyrate dehydrogenase family
protein; n=16; Gammaproteobacteria|Rep:
3-hydroxyisobutyrate dehydrogenase family protein -
Pseudomonas fluorescens (strain Pf-5 / ATCC BAA-477)
Length = 298
Score = 112 bits (269), Expect = 1e-23
Identities = 66/209 (31%), Positives = 108/209 (51%), Gaps = 5/209 (2%)
Frame = +3
Query: 183 NVAFLGLGNMGGFMAANLVKKGF--TVRGYDPSKDA--LNAAAKNGVTPANSIXXXXXXX 350
++ F G+G MG M L+ G+ TV +P K A + A A+ TPA
Sbjct: 7 SLGFAGIGLMGLPMCRRLLAAGYPLTVWNRNPEKCAPLVAAGARQVATPAQ----LCADA 62
Query: 351 XXXXSILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFP-IALEKGLGFT 527
L + +VV +V G G+ A+ G LL+D S+++P +++ +A +G+ +
Sbjct: 63 DLMLMCLANTEVVREVVFGPQGIAQGARAGQLLLDLSSLEPTATREMAAELAASRGVAWV 122
Query: 528 DAPVSGGVMGAQNATLAFMAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNML 707
DAPVSGG GA+ +LA M GG D ER P+L +G + H G +G+GQV K N M+
Sbjct: 123 DAPVSGGTPGAEAGSLAIMVGGEATDVERVRPVLLTLGQRVTHMGAVGAGQVTKACNQMI 182
Query: 708 MGITGMAXAECMXMGIKMGLXPKVLLDVL 794
+ + AE + + + G+ +++ + L
Sbjct: 183 VACNALVIAEVVALAERSGVDARLIAEAL 211
>UniRef50_Q2UHA9 Cluster: Predicted dehydrogenase; n=16;
Pezizomycotina|Rep: Predicted dehydrogenase -
Aspergillus oryzae
Length = 363
Score = 112 bits (269), Expect = 1e-23
Identities = 87/249 (34%), Positives = 126/249 (50%), Gaps = 26/249 (10%)
Frame = +3
Query: 150 ARRAYSSNT--DKNVAFLGLGNMGGFMAANL--------------VKKGFTVRGYDPSKD 281
A RA+SS+ D F+GLG MG MA NL + + R + +++
Sbjct: 30 ATRAFSSSLRRDDTWGFIGLGQMGYAMAKNLRAKIPASDTLIIRDINENTAKRFVEETQE 89
Query: 282 AL-NAAAKNGVTPANSIXXXXXXXXXXXSILTS---NKVVLDVY--LGKDGVVAHAKKGS 443
A+ N+ AK + I+TS + V +V+ + + G + +K
Sbjct: 90 AVRNSGAKEDTSKVLIAQNAREVAEQSTVIVTSLPEPEHVKNVFYCMLRHGELPALEKER 149
Query: 444 LLIDSSTIDPNVPKQIFPIALEKGLG-FTDAPVSGGVMGAQNATLAFMAGGRKEDFE--- 611
L ID+STIDP ++I G F DAP+SGGV+GA+ TL+FM G + E
Sbjct: 150 LFIDTSTIDPASSREIANAIHTTRQGRFVDAPMSGGVVGARAGTLSFMFGASSQTGELVD 209
Query: 612 RSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMGITGMAXAECMXMGIKMGLXPKVLLDV 791
R +L +MG K +H G G+G AKL NN L+ I +A AE M +GI+ GL PKVL D+
Sbjct: 210 RVQSVLMLMGKKAWHMGNSGTGVSAKLANNYLLAINNIATAEVMNLGIRCGLDPKVLADM 269
Query: 792 LNNSSXRSW 818
+N S+ R W
Sbjct: 270 INTSTGRCW 278
>UniRef50_Q0LNZ7 Cluster: 3-hydroxyisobutyrate dehydrogenase
precursor; n=1; Herpetosiphon aurantiacus ATCC
23779|Rep: 3-hydroxyisobutyrate dehydrogenase precursor
- Herpetosiphon aurantiacus ATCC 23779
Length = 301
Score = 111 bits (268), Expect = 2e-23
Identities = 67/212 (31%), Positives = 101/212 (47%), Gaps = 1/212 (0%)
Frame = +3
Query: 186 VAFLGLGNMGGFMAANLVKKGFTVR-GYDPSKDALNAAAKNGVTPANSIXXXXXXXXXXX 362
+ +GLG MG MA+NL++ G+ + G ++A A G A S
Sbjct: 6 IGLIGLGAMGAPMASNLLQAGYQLTVGVHQRREAAEQLALQGAIIAESYQALGENSDIVI 65
Query: 363 SILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAPVS 542
+++ V LG +G GS+ ID STI P + I E+ + DAPVS
Sbjct: 66 TMVPDAPQVEAALLGTNGAAYGMAAGSICIDMSTIAPTASRAIAAKLAERQIAMLDAPVS 125
Query: 543 GGVMGAQNATLAFMAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMGITG 722
GG A+ LA M GG FER +L+V+G + G GSG V KL NN+ + I
Sbjct: 126 GGPARAKTGELAIMVGGEPSTFERCQAVLEVLGGAVSYIGASGSGSVVKLCNNLAISIIA 185
Query: 723 MAXAECMXMGIKMGLXPKVLLDVLNNSSXRSW 818
MA E + G+ G+ + + +VL N++ ++
Sbjct: 186 MANIEALAFGVANGVEAETIRNVLLNATASNY 217
>UniRef50_A1WM48 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=1;
Verminephrobacter eiseniae EF01-2|Rep:
3-hydroxyisobutyrate dehydrogenase - Verminephrobacter
eiseniae (strain EF01-2)
Length = 301
Score = 111 bits (268), Expect = 2e-23
Identities = 70/211 (33%), Positives = 99/211 (46%)
Frame = +3
Query: 192 FLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGVTPANSIXXXXXXXXXXXSIL 371
F+GLGNMGG M L+ G TV +D AL A +G +S L
Sbjct: 9 FIGLGNMGGPMVKRLLHAGHTVLVFDRDAAALARAVADGAQARSSALDVADAAATIFLSL 68
Query: 372 TSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAPVSGGV 551
V V +DG++ K+ ++D STI P +G+ + D+PVSGG+
Sbjct: 69 PDGPAVQHVISAQDGLL-QGKRVKCVVDLSTIGPRAAVAASQALGARGIAYVDSPVSGGI 127
Query: 552 MGAQNATLAFMAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMGITGMAX 731
GA+ TLA M + ++ P+LK G + G GQ KL NN+L
Sbjct: 128 GGAERGTLAVMTACPQPLYDELAPVLKNFGRLFYMGAGPGLGQTMKLANNLLSAAAVAIT 187
Query: 732 AECMXMGIKMGLXPKVLLDVLNNSSXRSWST 824
+E M MG K GL P V+L+V+N S R+ +T
Sbjct: 188 SEAMAMGAKAGLDPGVMLEVINAGSGRNSAT 218
>UniRef50_Q0URA2 Cluster: Putative uncharacterized protein; n=1;
Phaeosphaeria nodorum|Rep: Putative uncharacterized
protein - Phaeosphaeria nodorum (Septoria nodorum)
Length = 325
Score = 111 bits (268), Expect = 2e-23
Identities = 93/256 (36%), Positives = 124/256 (48%), Gaps = 22/256 (8%)
Frame = +3
Query: 168 SNTDKNVAFLGLGNMGGFMAANLVK---KGFTVRGYDPSKDALNAAAKN--GVTPANSIX 332
S +K VAF+GLG MG MA NL K T+ D S DAL + G P +++
Sbjct: 2 SPPEKTVAFIGLGVMGYPMALNLRKGLDDSHTLLVCDVSSDALARFQNDAKGHGPVSTVD 61
Query: 333 XXXXXXXXXXSILT---SNKVVLDVYLGKD-GVVAHAKKGS------LLIDSSTIDPN-- 476
+++T + V VYL G++A A+ S L+++ TI+ +
Sbjct: 62 GGYQAVQLADTVITMLPDSNAVKKVYLDPSTGILAGAEANSGTKSDKLIMECGTIETSTI 121
Query: 477 --VPKQIFPIALEKGLGFTDAPVSGGVMGAQNATLAFMAGGR-KEDFERSLPLLKVMGAK 647
V K + L F DAPVSGG MGAQ+ TLAFMAG K F R L MG
Sbjct: 122 LEVAKATSSSKAAENLTFVDAPVSGGPMGAQDGTLAFMAGANNKAIFPRVKGYLSHMGKP 181
Query: 648 Q--FHCGQIGSGQVAKLTNNMLMGITGMAXAECMXMGIKMGLXPKVLLDVLNNSSXRSWS 821
F CG IG+G K+ NN L IT +A +E + +G KMGL +L DV+N S + W
Sbjct: 182 DAIFLCGDIGAGTAFKVINNYLSAITSLAASEALNIGTKMGLDVALLTDVINVSGGQCWV 241
Query: 822 TXXVLSXPRTGAHRSV 869
T S P G +V
Sbjct: 242 TSK--SNPVPGVQANV 255
>UniRef50_Q0F1Y7 Cluster: 6-phosphogluconate dehydrogenase,
NAD-binding protein; n=1; Mariprofundus ferrooxydans
PV-1|Rep: 6-phosphogluconate dehydrogenase, NAD-binding
protein - Mariprofundus ferrooxydans PV-1
Length = 289
Score = 111 bits (267), Expect = 2e-23
Identities = 66/205 (32%), Positives = 101/205 (49%)
Frame = +3
Query: 180 KNVAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGVTPANSIXXXXXXXXXX 359
+N+ F+GLG MG MAAN++K+G + Y+ + + A G A+
Sbjct: 3 QNIGFIGLGIMGEAMAANILKQGHPLIVYNRTVEKAAALVDAGAMVADKPSLVADASDVI 62
Query: 360 XSILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAPV 539
+LT + V V G++G+++ +G +I+ ST+ K+ + G+ DAPV
Sbjct: 63 ILMLTGEEAVDAVLFGEEGLLSGDCEGKTVINMSTVPVECSKRWAKELADHGMTLIDAPV 122
Query: 540 SGGVMGAQNATLAFMAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMGIT 719
SG + AQ TL +AGG + PLL MG K +CG GSG KL N+L+GI
Sbjct: 123 SGSKVPAQTGTLVILAGGPEAAVRAQEPLLLSMGKKVIYCGPTGSGSAMKLAINLLLGIM 182
Query: 720 GMAXAECMXMGIKMGLXPKVLLDVL 794
AE + + GL + LLD +
Sbjct: 183 TEGIAEALHLAESSGLASETLLDAV 207
>UniRef50_A5P0V0 Cluster: 6-phosphogluconate dehydrogenase,
NAD-binding precursor; n=3; Rhizobiales|Rep:
6-phosphogluconate dehydrogenase, NAD-binding precursor
- Methylobacterium sp. 4-46
Length = 299
Score = 111 bits (267), Expect = 2e-23
Identities = 73/216 (33%), Positives = 107/216 (49%), Gaps = 5/216 (2%)
Frame = +3
Query: 186 VAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGVTPANSIXXXXXXXXXXXS 365
VAF+GLG MG MA NLV KGF VRGYD ++ A A+ G A+++
Sbjct: 6 VAFVGLGAMGLPMAQNLVAKGFPVRGYDVRPESRAALARAGGEAADTLRAAAAGAGALVL 65
Query: 366 ILTSNKVVLDVYLG----KDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDA 533
++ + V G +G + + +I +T P + + G F DA
Sbjct: 66 MVVNAAQAEAVLFGGGAPAEGALEVLAPDAAVILMATCPPQAVEGLAARVAAAGRRFVDA 125
Query: 534 PVSGGVMGAQNATLAFMAGGRKEDFERSLPLLKVMGAKQFHCG-QIGSGQVAKLTNNMLM 710
PVSGGV+GA+ +L MA E F PLL +GA+ FH G + G G K N +L
Sbjct: 126 PVSGGVVGAEAGSLTVMAAAPAEVFGAVRPLLDAVGARIFHVGTRPGQGATVKAVNQLLC 185
Query: 711 GITGMAXAECMXMGIKMGLXPKVLLDVLNNSSXRSW 818
G+ A AE + + ++G+ V+L++L+ SS SW
Sbjct: 186 GVHIAAAAEALSLAERVGVDLPVVLEILSGSSAASW 221
>UniRef50_Q6C351 Cluster: Yarrowia lipolytica chromosome F of strain
CLIB122 of Yarrowia lipolytica; n=1; Yarrowia
lipolytica|Rep: Yarrowia lipolytica chromosome F of
strain CLIB122 of Yarrowia lipolytica - Yarrowia
lipolytica (Candida lipolytica)
Length = 334
Score = 111 bits (267), Expect = 2e-23
Identities = 81/242 (33%), Positives = 116/242 (47%), Gaps = 17/242 (7%)
Frame = +3
Query: 150 ARRAYSSNTDKNVAFLGLGNMGGFMAANLVKK------GFTVRGYDPSKDALNAAAKNG- 308
A R ++ D + F+GLG MG MA NL KK V +D +K AL AK+
Sbjct: 12 ALRPLRASRDLSYGFIGLGRMGLPMALNLQKKLPGVDADSKVNVFDMNKAALEQIAKDKD 71
Query: 309 -----VTPANSIXXXXXXXXXXXSILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDP 473
+ S ++L V VY + K + +D STID
Sbjct: 72 PKGAQLEVLGSAVDVASKSDVIFTMLPEPVHVRGVYTDLVNNLGD-KTSKIFVDCSTIDT 130
Query: 474 NVPKQIFPIALEK--GLGFTDAPVSGGVMGAQNATLAFMAGGRKED---FERSLPLLKVM 638
+ + +K F DAPVSGGV+GA+ TL FM G K+ +++ LLK+M
Sbjct: 131 QTSIECGKLVTDKDASAAFVDAPVSGGVVGAEKGTLTFMVGCNKDKQQVYKQVEELLKLM 190
Query: 639 GAKQFHCGQIGSGQVAKLTNNMLMGITGMAXAECMXMGIKMGLXPKVLLDVLNNSSXRSW 818
G + +CG G G AKL NN L+ +T +A AE + K+G K+ D++N+SS RSW
Sbjct: 191 GGRIVNCGTQGQGLAAKLANNYLLAVTNVATAEAFHLAEKLGCDLKLFSDIVNSSSGRSW 250
Query: 819 ST 824
S+
Sbjct: 251 SS 252
>UniRef50_Q7WCG3 Cluster: Putative uncharacterized protein; n=2;
Bordetella|Rep: Putative uncharacterized protein -
Bordetella parapertussis
Length = 296
Score = 111 bits (266), Expect = 3e-23
Identities = 70/217 (32%), Positives = 107/217 (49%), Gaps = 2/217 (0%)
Frame = +3
Query: 180 KNVAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGVTPANSIXXXXXXXXXX 359
K VAF+G+GNMG MA + GF + D + D L A A+ GV SI
Sbjct: 5 KTVAFIGVGNMGAPMARCARRAGFELIVCDRNPDVLAAFAQEGVRVTASISDCAAADAVV 64
Query: 360 XSILTSNKVVLDVYLGKDGVVAHAKKGS--LLIDSSTIDPNVPKQIFPIALEKGLGFTDA 533
+L ++ +++ LG G+ G ++ ST P+ + + G DA
Sbjct: 65 V-LLANDAQIMETMLGGQGLAQAVPAGHRPIVCMMSTTLPDTLRALEAPLAAVGARLVDA 123
Query: 534 PVSGGVMGAQNATLAFMAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMG 713
PVSGG++GA+ TL M GG D E PL++ MG + FHCG +GS ++AK+ NNML
Sbjct: 124 PVSGGIVGAEAGTLTIMMGGETADVEAVRPLMQAMGERLFHCGALGSAEIAKVINNMLCV 183
Query: 714 ITGMAXAECMXMGIKMGLXPKVLLDVLNNSSXRSWST 824
AE + + G+ + L +L+ S+ ++ T
Sbjct: 184 ANMFLTAEAIELAESHGVAFESLTPILSVSTGLNFLT 220
>UniRef50_Q39MY1 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=2;
Burkholderia sp. 383|Rep: 3-hydroxyisobutyrate
dehydrogenase - Burkholderia sp. (strain 383)
(Burkholderia cepacia (strain ATCC 17760/ NCIB 9086 /
R18194))
Length = 303
Score = 111 bits (266), Expect = 3e-23
Identities = 71/226 (31%), Positives = 113/226 (50%), Gaps = 1/226 (0%)
Frame = +3
Query: 183 NVAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGVTPANSIXXXXXXXXXXX 362
++ FLGLG MG MA L+ + + YDPS A+ G S
Sbjct: 6 DIGFLGLGKMGAPMAERLLGQACRLHVYDPSAQAVAPFVDGGAVAHASPRAVADAASIVF 65
Query: 363 SILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAPVS 542
+ L + V L V LG DGVV H L ++ STI ++ ++I ++G+ DAPVS
Sbjct: 66 ACLPNRDVSLAVGLGPDGVV-HGSAVRLYVEMSTIGQDMIERIGEGLAQRGIDIVDAPVS 124
Query: 543 GGVMGAQNATLAFMAGGRKEDFERSLPLLKVMGAKQFHCG-QIGSGQVAKLTNNMLMGIT 719
GG A+ TLA + G E+ PLL+ +G + F G + G Q+ K+ NN++M
Sbjct: 125 GGPSAARAGTLAMLVSGMPSAVEQVSPLLERIGKEVFPMGDRPGMAQIMKIVNNVVMAAN 184
Query: 720 GMAXAECMXMGIKMGLXPKVLLDVLNNSSXRSWSTXXVLSXPRTGA 857
+ AE + MG K GL ++ ++++ S +S++ ++S +GA
Sbjct: 185 LVVCAEGLAMGAKAGLDADRMMRLIDSGSGQSFACSKIMSRAVSGA 230
>UniRef50_Q13PY3 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=2;
Burkholderiales|Rep: 3-hydroxyisobutyrate dehydrogenase
- Burkholderia xenovorans (strain LB400)
Length = 302
Score = 110 bits (265), Expect = 4e-23
Identities = 70/214 (32%), Positives = 101/214 (47%), Gaps = 1/214 (0%)
Frame = +3
Query: 186 VAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGVTPANSIXXXXXXXXXXXS 365
+ +GLGN+G A L+ G + YD +A+ G A
Sbjct: 3 IGLIGLGNIGQHFATRLLAAGHPLVVYDTRDEAMQRFGALGAELAKDTVDLASRAEVVFL 62
Query: 366 ILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAPVSG 545
L VV +V G GV + +++D ST P+V I ++ + F APVSG
Sbjct: 63 SLPLPSVVEEVATGPHGV-SQGSSVRIVVDLSTTGPSVSNVIARKLADRHIQFLGAPVSG 121
Query: 546 GVMGAQNATLAFMAGGRKEDFERSLPLLKVMGAKQFHCGQ-IGSGQVAKLTNNMLMGITG 722
G + A+ TL MA G E FE P L+V+G F+ G G GQ K+ NN L +
Sbjct: 122 GTVAAEKGTLTVMAAGPMEAFETVEPWLRVIGKNIFYLGSGAGLGQTMKIINNTLCAVGM 181
Query: 723 MAXAECMXMGIKMGLXPKVLLDVLNNSSXRSWST 824
+A E + G+K GL ++LD+LN SS RS++T
Sbjct: 182 VASCEALVFGVKAGLDSAMMLDILNVSSGRSFAT 215
>UniRef50_A0K0Z6 Cluster: 6-phosphogluconate dehydrogenase,
NAD-binding precursor; n=2; Micrococcineae|Rep:
6-phosphogluconate dehydrogenase, NAD-binding precursor
- Arthrobacter sp. (strain FB24)
Length = 301
Score = 110 bits (265), Expect = 4e-23
Identities = 73/204 (35%), Positives = 102/204 (50%), Gaps = 3/204 (1%)
Frame = +3
Query: 171 NTDKNVAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGVTPANSIXXXXXXX 350
NT +A +GLG MGG MAA L K G+ V G+DPS+ A AAA+ G+ S+
Sbjct: 2 NTSTRIAVIGLGAMGGAMAATLHKAGWDVTGFDPSEAARTAAAQTGIATTASLDDVAGTP 61
Query: 351 XXXXSILTSNKVVLDV--YLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGF 524
S+ ++ V V L G VA +ID++T +P KQ+ +A +G F
Sbjct: 62 YAVLSLPAASIVETTVPRLLAVPGTVA-------IIDTTTSEPATSKQMAHLADTQGAAF 114
Query: 525 TDAPVSGGVMGAQNATLAFMAGGRKEDFERSLP-LLKVMGAKQFHCGQIGSGQVAKLTNN 701
DAPVSGG GA + +L+ GG + P LL + G K H G GSG V KL NN
Sbjct: 115 VDAPVSGGRDGAASGSLSAFVGGTDAALAAAEPVLLALTGGKYSHIGGPGSGNVVKLLNN 174
Query: 702 MLMGITGMAXAECMXMGIKMGLXP 773
+L ++ E + + G+ P
Sbjct: 175 VLAAANLVSVGEALGVAKAYGIDP 198
>UniRef50_A0FZ96 Cluster: 6-phosphogluconate dehydrogenase,
NAD-binding; n=1; Burkholderia phymatum STM815|Rep:
6-phosphogluconate dehydrogenase, NAD-binding -
Burkholderia phymatum STM815
Length = 305
Score = 110 bits (265), Expect = 4e-23
Identities = 64/218 (29%), Positives = 114/218 (52%), Gaps = 1/218 (0%)
Frame = +3
Query: 186 VAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGVTPANSIXXXXXXXXXXXS 365
+ ++GLG MGG +A +L+ K + + +D ++ A+ A + G T A +
Sbjct: 3 IGYIGLGAMGGALARHLIGK-YPLSVFDLNRKAVEAFVELGATAAATPAELARNSDVVLL 61
Query: 366 ILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAPVSG 545
L + V V G DG V G ++ID ++ P + + G+ DAPVSG
Sbjct: 62 CLPRSSDVHSVLFGPDGAVEGLSDGKIVIDQTSGVPAETRDFARQLADIGVALFDAPVSG 121
Query: 546 GVMGAQNATLAFMAGGRKEDFERSLPLLKVMGAKQFHCGQ-IGSGQVAKLTNNMLMGITG 722
+ A T++ +A G K+ FE++LP+L+ + FHCG+ +G+GQ K NNM+
Sbjct: 122 AMATAIAGTISIIASGPKDAFEKTLPVLQSISPNVFHCGERVGNGQTMKTVNNMMNVSCR 181
Query: 723 MAXAECMXMGIKMGLXPKVLLDVLNNSSXRSWSTXXVL 836
+A E + MG K GL +++ + +N ++ R++++ +L
Sbjct: 182 LATLEVVAMGRKFGLPLELMTEAINATTARNYTSQGML 219
>UniRef50_Q84H84 Cluster: Putative oxidoreductase; n=1; Arthrobacter
sp. BP2|Rep: Putative oxidoreductase - Arthrobacter sp.
BP2
Length = 278
Score = 110 bits (264), Expect = 5e-23
Identities = 71/216 (32%), Positives = 110/216 (50%), Gaps = 3/216 (1%)
Frame = +3
Query: 180 KNVAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGVTPANSI-XXXXXXXXX 356
K + F+GLG MG MA NL + GF V GYD + + A G+T A ++
Sbjct: 3 KKIGFVGLGTMGLPMAVNLNRAGFEVIGYDAFEGSRQKAIAAGITMAETLKDVAEQADDA 62
Query: 357 XXSILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKG-LGFTDA 533
S++ +DV LG+DG+++ K +I ST+DP+ ++ E G + A
Sbjct: 63 IVSMVRDYAQNVDVILGQDGLLSANPKNLTIIVMSTLDPDTMNELGQQVEEHGEVRLIAA 122
Query: 534 PVSGGVMGAQNATLAFMAGGRKEDFERSLPLLKVMGAKQFHCG-QIGSGQVAKLTNNMLM 710
VSGG GA+ TL+ MA G ++ + P +G+ F+ G + G+ Q AKL NN+++
Sbjct: 123 AVSGGSTGAEAGTLSIMASGAEDVVTAASPYFDAVGSNTFYYGSKPGNSQAAKLVNNLVL 182
Query: 711 GITGMAXAECMXMGIKMGLXPKVLLDVLNNSSXRSW 818
GI A AE + G + L LL++ S+ SW
Sbjct: 183 GINMNAVAEGLKFGAQYNLPEAELLNLFKVSTGDSW 218
>UniRef50_A3H5R1 Cluster: 6-phosphogluconate dehydrogenase,
NAD-binding; n=1; Caldivirga maquilingensis IC-167|Rep:
6-phosphogluconate dehydrogenase, NAD-binding -
Caldivirga maquilingensis IC-167
Length = 295
Score = 109 bits (262), Expect = 9e-23
Identities = 71/213 (33%), Positives = 107/213 (50%), Gaps = 2/213 (0%)
Frame = +3
Query: 183 NVAFLGLGNMGGFMAANLVKKGFTVRGYDPSKD-ALNAAAKNGVTPANSIXXXXXXXXXX 359
NV +GLG MG +A NL G + ++ + A+ A +N V N+
Sbjct: 3 NVGLIGLGTMGWRIAKNLKDDGLLIGVFNRTMSKAIKFAEENKVNVFNNPAELARNVDVV 62
Query: 360 XSILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAPV 539
SI++ + V + LG++GV+ K+GSL+I+ STI P+ ++ EKG DAP+
Sbjct: 63 LSIVSDDDAVKSIMLGENGVINGIKQGSLVIEMSTISPSTSIELANKIKEKGGLMVDAPI 122
Query: 540 SGGVMGAQNATLAFMAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMGIT 719
G + + + GG +E +ER+ ++K H G G G AKL NN L+G
Sbjct: 123 IGTSILIEKREAVVLIGGEREAYERAYEVVKHFARYVVHVGPNGYGLYAKLINNALLGSY 182
Query: 720 GMAXAECMXMGIKMGLXPKVLLDVLNN-SSXRS 815
A AE + +G MGL V++DVL SS RS
Sbjct: 183 VAALAEVVNLGEAMGLSSSVIMDVLTKLSSARS 215
>UniRef50_A3VLN6 Cluster: Oxidoreductase; n=1; Rhodobacterales
bacterium HTCC2654|Rep: Oxidoreductase - Rhodobacterales
bacterium HTCC2654
Length = 293
Score = 109 bits (261), Expect = 1e-22
Identities = 64/200 (32%), Positives = 98/200 (49%), Gaps = 1/200 (0%)
Frame = +3
Query: 186 VAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGVTPANSIXXXXXXXXXXXS 365
V F GLGN+G MA L ++G + ++ S+ + GV A S
Sbjct: 3 VGFAGLGNIGALMAWRLQERGHDLVVWNRSQAKTQSFRDAGVPVAPSPADLARQVDVLCL 62
Query: 366 ILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFP-IALEKGLGFTDAPVS 542
+T K + V G DG+V + ++++D ST+ P+ +QI + E G + DAPVS
Sbjct: 63 CVTDAKALDAVLFGSDGIVGAGRVPAMIVDHSTVPPDATRQIAARVRAEAGAAWVDAPVS 122
Query: 543 GGVMGAQNATLAFMAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMGITG 722
GG+ GA LA GG D R+ P+L +G H G GSGQVAK N ++ ++
Sbjct: 123 GGLAGAAAGQLAIFVGGEDADVTRAWPVLTTLGTTVTHLGPTGSGQVAKACNQVIGFLSF 182
Query: 723 MAXAECMXMGIKMGLXPKVL 782
A AE + + + + P+ L
Sbjct: 183 AALAEALALAARYDIAPRDL 202
>UniRef50_A0LTQ8 Cluster: 6-phosphogluconate dehydrogenase,
NAD-binding precursor; n=1; Acidothermus cellulolyticus
11B|Rep: 6-phosphogluconate dehydrogenase, NAD-binding
precursor - Acidothermus cellulolyticus (strain ATCC
43068 / 11B)
Length = 305
Score = 109 bits (261), Expect = 1e-22
Identities = 70/212 (33%), Positives = 104/212 (49%), Gaps = 5/212 (2%)
Frame = +3
Query: 186 VAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNA-----AAKNGVTPANSIXXXXXXX 350
VA LGLG MG MAA L G + ++ +++ A AK TPA ++
Sbjct: 4 VAVLGLGAMGSAMAARLHDAGAELILWNRTRERAQALGERLGAKVAATPAEAVADVPVAL 63
Query: 351 XXXXSILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTD 530
+ L + V DV+LG DGVVA A+ G ++ + ST++P V + I P KG D
Sbjct: 64 ----TSLADRRAVEDVFLGPDGVVAGARPGLVVAELSTVEPEVARAIAPELRAKGADILD 119
Query: 531 APVSGGVMGAQNATLAFMAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLM 710
PVSG V A+ L M GG + P+L ++G + FH G +GSG KL N ++
Sbjct: 120 VPVSGSVAVAREGGLTLMVGGEDASLDAIRPVLDIIGRRIFHLGPLGSGAAMKLAVNTVI 179
Query: 711 GITGMAXAECMXMGIKMGLXPKVLLDVLNNSS 806
A AE + + + G+ + DV +S+
Sbjct: 180 HGLNAALAEGLVLAERAGIPRSLAYDVFASSA 211
>UniRef50_Q7WG50 Cluster: Probable oxidoreductase; n=1; Bordetella
bronchiseptica|Rep: Probable oxidoreductase - Bordetella
bronchiseptica (Alcaligenes bronchisepticus)
Length = 316
Score = 108 bits (259), Expect = 2e-22
Identities = 71/207 (34%), Positives = 100/207 (48%), Gaps = 1/207 (0%)
Frame = +3
Query: 186 VAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGVTPANSIXXXXXXXXXXXS 365
+AFLGLG MG MA NLVK G V GYD + AL+A A+ G A S +
Sbjct: 6 IAFLGLGAMGLPMACNLVKGGHAVTGYDLNPQALDALAQAGGQRAASAREAAAGAALVIA 65
Query: 366 ILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAPVSG 545
+L + + G DG + G+L I+ STI P I E+G+ D+PV
Sbjct: 66 MLPTATHIQAALEGADGALQGMDPGALFINMSTILPQETDLIAQRLAERGMRMLDSPVGR 125
Query: 546 GVMGAQNATLAFMAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMGIT-G 722
M AQ TL +A G +D R+ L MG + CG++G G K+ NN MGI+
Sbjct: 126 SAMEAQRGTLLILASGSAQDKARARDALLCMGNQVIDCGEVGGGSRVKVVNN-FMGISLN 184
Query: 723 MAXAECMXMGIKMGLXPKVLLDVLNNS 803
AE + + GL ++ L+V+ +
Sbjct: 185 ALTAEALTLAEASGLSVELALEVMRGT 211
>UniRef50_Q3DYV4 Cluster: NADP oxidoreductase, coenzyme
F420-dependent:6-phosphogluconate dehydrogenase,
NAD-binding; n=2; Chloroflexus|Rep: NADP oxidoreductase,
coenzyme F420-dependent:6-phosphogluconate
dehydrogenase, NAD-binding - Chloroflexus aurantiacus
J-10-fl
Length = 289
Score = 107 bits (258), Expect = 3e-22
Identities = 67/203 (33%), Positives = 104/203 (51%)
Frame = +3
Query: 186 VAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGVTPANSIXXXXXXXXXXXS 365
+A +GLG MG MA L+K GF V G++ S L+ A G+ P +
Sbjct: 3 IALIGLGLMGRPMARTLLKAGFNVTGWNRSP--LDPALTEGI-PLAATLAEAAQAETLIL 59
Query: 366 ILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAPVSG 545
+L+ + V ++ D ++ ++G L+ID + DP + +G+G+ DAPVSG
Sbjct: 60 MLSDSTAVAELLSRLDPLL---REGQLIIDMGSSDPRHSQTHATTLANRGIGWVDAPVSG 116
Query: 546 GVMGAQNATLAFMAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMGITGM 725
G GA TLA M GG D ER+ P+L+ +G + H G G+G K+ N +++G+T
Sbjct: 117 GPEGAAAGTLAIMVGGTASDVERAEPILRALG-RPTHVGPPGAGHTVKVINQLIVGLTIQ 175
Query: 726 AXAECMXMGIKMGLXPKVLLDVL 794
A AE M + G+ P +L L
Sbjct: 176 AVAEAMVLAEAYGIDPALLRTAL 198
>UniRef50_A5GPC0 Cluster: Hydroxyacid dehydrogenase/reductase family
protein; n=14; Cyanobacteria|Rep: Hydroxyacid
dehydrogenase/reductase family protein - Synechococcus
sp. (strain WH7803)
Length = 302
Score = 107 bits (258), Expect = 3e-22
Identities = 64/218 (29%), Positives = 115/218 (52%), Gaps = 6/218 (2%)
Frame = +3
Query: 186 VAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGVTPANSIXXXXXXXXXXXS 365
+AF+GLG +G +AANL + G++++ + S+ A N + + PA +
Sbjct: 12 LAFVGLGALGLPIAANLHRAGYSLQVHTRSRSAENDPSLHQGDPAAATLCCASPADAVQG 71
Query: 366 -----ILTSNKVVLDVYL-GKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFT 527
+ S+ ++ L G +G +GSL+ID STI P+ +++ +G+ +
Sbjct: 72 CQALVLCVSDDAAVEAVLWGDNGAGPALAEGSLVIDCSTISPSTSQRMARRLAHRGVRYL 131
Query: 528 DAPVSGGVMGAQNATLAFMAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNML 707
DAPV+GG GA+ TL + GG D +R++P+L+ +G H G +GSGQ K N +L
Sbjct: 132 DAPVTGGTEGAKAGTLTVLCGGSDADLDRAMPVLETIGGSIHHFGAVGSGQQVKAVNQVL 191
Query: 708 MGITGMAXAECMXMGIKMGLXPKVLLDVLNNSSXRSWS 821
+ + A AE + +G + L + +++ L + + SW+
Sbjct: 192 VAGSYAAVAEAIALGQHLQLPMQQVVNALRHGAAGSWA 229
>UniRef50_A0G5F9 Cluster: 6-phosphogluconate dehydrogenase,
NAD-binding; n=2; Burkholderia|Rep: 6-phosphogluconate
dehydrogenase, NAD-binding - Burkholderia phymatum
STM815
Length = 307
Score = 107 bits (258), Expect = 3e-22
Identities = 72/227 (31%), Positives = 109/227 (48%), Gaps = 1/227 (0%)
Frame = +3
Query: 147 AARRAYSSNTDKNVAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGVTPANS 326
++ +A S + F+G+G MG MA L++ G + +D + A+ G A S
Sbjct: 2 SSSQASSQQRGPLLGFVGVGTMGRPMARRLIEAGHALVVFDRDEAAVAELKAIGAQAAAS 61
Query: 327 IXXXXXXXXXXXSILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIAL 506
+ + L + + V LG DG + +L+D ST+ V K++ L
Sbjct: 62 VREIADSARIVFTSLPTPAIFRQVALG-DGGLIEGSAIKVLVDLSTVGSRVEKEVAQGLL 120
Query: 507 EKGLGFTDAPVSGGVMGAQNATLAFMAGGRKEDFERSLPLLKVMGAKQFHCG-QIGSGQV 683
KG+ DAPVSGG GA+ TLA MA G E L V+G K F G + G GQ+
Sbjct: 121 AKGVETVDAPVSGGAAGAKKGTLAIMAAGSPVALEEVRGLFDVLG-KAFVVGDKAGQGQL 179
Query: 684 AKLTNNMLMGITGMAXAECMXMGIKMGLXPKVLLDVLNNSSXRSWST 824
KL NNML +E G++ GL P+V++ V+N S ++ +T
Sbjct: 180 LKLLNNMLSSTAFAITSEAFVAGVRGGLDPEVMMSVINAGSGKNGAT 226
>UniRef50_Q89HA0 Cluster: Oxidoreductase; n=1; Bradyrhizobium
japonicum|Rep: Oxidoreductase - Bradyrhizobium japonicum
Length = 313
Score = 107 bits (257), Expect = 4e-22
Identities = 64/207 (30%), Positives = 96/207 (46%), Gaps = 1/207 (0%)
Frame = +3
Query: 177 DKNVAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGVTPANSIXXXXXXXXX 356
D+ +LGLG MG M L+K G+ V ++ S+ + + G S
Sbjct: 23 DERFGYLGLGLMGTPMTRRLLKAGYQVSVWNRSEGKVVPIVEAGARHGASPRDVMAGSDI 82
Query: 357 XXSILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFP-IALEKGLGFTDA 533
+T V +V G +G+ G L++D S+I P+ + + + G G+ DA
Sbjct: 83 VFMCVTDAAAVEEVIFGAEGLSTAPGAGKLVVDFSSIHPDAARDLATRLKAANGAGWIDA 142
Query: 534 PVSGGVMGAQNATLAFMAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMG 713
PVSGG GA+ TLA MAGG D ER P + M + H G G+GQ AKL N +++G
Sbjct: 143 PVSGGTKGAEEGTLAIMAGGDASDIERVRPYVLTMARRFTHMGPTGAGQTAKLCNQVIVG 202
Query: 714 ITGMAXAECMXMGIKMGLXPKVLLDVL 794
AE + + G+ L + L
Sbjct: 203 CAMAVLAEATRLAVNAGIDANRLPEAL 229
>UniRef50_Q1YHQ4 Cluster: Putative 2-hydroxy-3-oxopropionate
reductase; n=1; Aurantimonas sp. SI85-9A1|Rep: Putative
2-hydroxy-3-oxopropionate reductase - Aurantimonas sp.
SI85-9A1
Length = 292
Score = 107 bits (257), Expect = 4e-22
Identities = 72/212 (33%), Positives = 102/212 (48%), Gaps = 5/212 (2%)
Frame = +3
Query: 186 VAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGVTPANSIXXXXXXXXXXXS 365
+ F+GLG MG L + + V G+D + ++AAA GV PA S+
Sbjct: 4 IGFIGLGLMGSGFTKRLRELDYRVIGHDREAEKVSAAAAWGVEPAGSLAALCAEADIIAL 63
Query: 366 ILTSNKVVLDVYLGKDGVVAHAK-KGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAPVS 542
LT++ V V G DG+VA K G ++D ST + V Q+ G F DAPVS
Sbjct: 64 CLTTSDAVASVVTGADGLVASRKLSGRTVVDFSTTEMAVTHQVAAAIEAVGGRFVDAPVS 123
Query: 543 GGVMGAQNATLAFMAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMGITG 722
GG A+ TLA M GG ++ E + P+L+ +G + H G IG+GQ KL N +L
Sbjct: 124 GGPGAAETGTLAIMFGGSEQAAEAARPMLEQLG-RATHMGAIGTGQATKLVNQVLCLTNY 182
Query: 723 MAXAECMXM----GIKMGLXPKVLLDVLNNSS 806
AE + + G+ P L L NS+
Sbjct: 183 CVAAEALRLAQAYGVDAAKIPHALEPGLGNSA 214
>UniRef50_Q13LQ9 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=11;
Proteobacteria|Rep: 3-hydroxyisobutyrate dehydrogenase -
Burkholderia xenovorans (strain LB400)
Length = 296
Score = 107 bits (257), Expect = 4e-22
Identities = 73/218 (33%), Positives = 106/218 (48%), Gaps = 6/218 (2%)
Frame = +3
Query: 180 KNVAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNA---AAKNGVTPANSIXXXXXXX 350
K V F+GLG MG M L K GF + + DA A A ++G N+
Sbjct: 5 KRVGFIGLGMMGAPMVQCLRKAGFEL--FIDDADAARADTLAEQSGSHRLNA--DNAGSL 60
Query: 351 XXXXSILTSNKVVLDVYLG---KDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLG 521
++L ++ +V V LG G A KG+++ID S+ +P + + + L
Sbjct: 61 DALITMLPNSAIVEAVVLGDGNNTGWAARLAKGAVVIDMSSSEPERSRALGKTLEAQRLA 120
Query: 522 FTDAPVSGGVMGAQNATLAFMAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNN 701
+ DAPVSGGV A+ TLA + GG + R PLL MG H G G+G AK NN
Sbjct: 121 YLDAPVSGGVKRAKEGTLAILVGGHADVLARCKPLLDAMGTNVLHIGTAGAGHAAKALNN 180
Query: 702 MLMGITGMAXAECMXMGIKMGLXPKVLLDVLNNSSXRS 815
+ + A E + + + G+ P+V+ DVLN S+ RS
Sbjct: 181 YVSAASVAATVEALQIASRFGIDPQVMTDVLNASTGRS 218
>UniRef50_A5VEA3 Cluster: 2-hydroxy-3-oxopropionate reductase; n=1;
Sphingomonas wittichii RW1|Rep:
2-hydroxy-3-oxopropionate reductase - Sphingomonas
wittichii RW1
Length = 264
Score = 107 bits (257), Expect = 4e-22
Identities = 62/211 (29%), Positives = 104/211 (49%)
Frame = +3
Query: 186 VAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGVTPANSIXXXXXXXXXXXS 365
+ F+GLG G +A NL+ G + G+D + L+ G T A S
Sbjct: 3 IGFIGLGVQGLPLALNLLDGGHELHGFDVRPEPLDELRDRGGTVAASPAELGAACEVVMI 62
Query: 366 ILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAPVSG 545
+ S++ V DV G+DGV+A A+ G +++ S++ + + ++G+ DAPVSG
Sbjct: 63 CVVSDQQVRDVLAGEDGVLASARPGLIVVLHSSVSTDTIAEAAKATRDRGVVLVDAPVSG 122
Query: 546 GVMGAQNATLAFMAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMGITGM 725
G GA+ T++FM GG + +R PL ++ G G G+ +AKL + + + M
Sbjct: 123 GAQGARARTMSFMVGGEEAALDRCQPLFELSGPNILRTGPAGTATLAKLAHQVAIIGNIM 182
Query: 726 AXAECMXMGIKMGLXPKVLLDVLNNSSXRSW 818
A AE + +G GL +++ + RSW
Sbjct: 183 AMAEAVRLGTAGGLSAEMVKQAVAGGLARSW 213
>UniRef50_Q8TT25 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=2;
Methanosarcina|Rep: 3-hydroxyisobutyrate dehydrogenase -
Methanosarcina acetivorans
Length = 300
Score = 107 bits (257), Expect = 4e-22
Identities = 66/220 (30%), Positives = 104/220 (47%), Gaps = 2/220 (0%)
Frame = +3
Query: 165 SSNTDKN--VAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGVTPANSIXXX 338
+S DKN V +GLG MG A+NL+ +G+ V Y+ +K+ + G T ++
Sbjct: 3 TSGCDKNITVGVIGLGIMGSSFASNLLSRGYNVHVYNRTKEKAQPLIERGATFHSTPREL 62
Query: 339 XXXXXXXXSILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGL 518
+ LT V V G+DG++ AKKG L ID STIDP+ + A + GL
Sbjct: 63 ASVADIIMTSLTDEAAVNSVAFGEDGLLNGAKKGCLWIDLSTIDPSSSVKHAEAAKKAGL 122
Query: 519 GFTDAPVSGGVMGAQNATLAFMAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTN 698
D PV G A L + GG +E + L +G + G G+G KL
Sbjct: 123 ERLDTPVVGSKDLASKGELIILVGGSQEVLRKHEKFLNKLGKSVIYLGADGNGHKMKLAI 182
Query: 699 NMLMGITGMAXAECMXMGIKMGLXPKVLLDVLNNSSXRSW 818
N+ +G+ + +E + K+G K ++ +NN+ R++
Sbjct: 183 NLHLGLLAESFSEALVFSQKLGFDAKTFVETINNTPIRNY 222
>UniRef50_A5FTT0 Cluster: 6-phosphogluconate dehydrogenase,
NAD-binding; n=3; Alphaproteobacteria|Rep:
6-phosphogluconate dehydrogenase, NAD-binding -
Acidiphilium cryptum (strain JF-5)
Length = 305
Score = 107 bits (256), Expect = 5e-22
Identities = 74/216 (34%), Positives = 107/216 (49%), Gaps = 1/216 (0%)
Frame = +3
Query: 180 KNVAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKN-GVTPANSIXXXXXXXXX 356
+ VAF+GLGNMG MAA LV G V G D + A A+ G T A
Sbjct: 3 QRVAFIGLGNMGWPMAARLVGGGCEVTGCDAVEGRAEAFAREVGGTAAADADAAARGAEF 62
Query: 357 XXSILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAP 536
++L ++ +V V + G+LLI+ S+ P V ++I + DAP
Sbjct: 63 IVTMLPNSALVESVVAAMRPSLG---AGALLIEMSSGIPGVTRRIAAGLEAAKVAMIDAP 119
Query: 537 VSGGVMGAQNATLAFMAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMGI 716
VSGGV A+ L+ M GG +D R+ LL++MG H G IG+GQ K NN++
Sbjct: 120 VSGGVARAKTGDLSIMTGGSADDCARAETLLRLMGTTITHVGDIGAGQAMKALNNLVSAG 179
Query: 717 TGMAXAECMXMGIKMGLXPKVLLDVLNNSSXRSWST 824
+ E + +G + GL P ++DVLN S+ + ST
Sbjct: 180 GFLIGVEALLIGQRFGLDPAQMVDVLNASTGMNNST 215
>UniRef50_A1UP64 Cluster: 6-phosphogluconate dehydrogenase,
NAD-binding; n=3; Mycobacterium|Rep: 6-phosphogluconate
dehydrogenase, NAD-binding - Mycobacterium sp. (strain
KMS)
Length = 305
Score = 106 bits (254), Expect = 9e-22
Identities = 68/204 (33%), Positives = 96/204 (47%)
Frame = +3
Query: 183 NVAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGVTPANSIXXXXXXXXXXX 362
NV F+GLG MG MA +LV G V ++ S+ ++ G A S
Sbjct: 2 NVGFIGLGVMGKPMAGHLVDAGHHVVVFNRSRAKVDELEARGAVGATSPAHAGEKADVVI 61
Query: 363 SILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAPVS 542
++L + V +V G GV + GSL+ID STI P+ I EK + F DAPVS
Sbjct: 62 TMLPDSPEVEEVLFGPAGVTTTLRPGSLVIDCSTISPDAAVAIGARLAEKDIAFVDAPVS 121
Query: 543 GGVMGAQNATLAFMAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMGITG 722
GG GA LA M GG ++ R+ +L + A H G +G+GQ+ K N ML+
Sbjct: 122 GGEAGAIAGALAVMMGGDEDAVRRAATVLDAVAATSVHVGPVGAGQLVKAANQMLVAGNI 181
Query: 723 MAXAECMXMGIKMGLXPKVLLDVL 794
E + + + G+ L VL
Sbjct: 182 ALVGEAVTLLQRTGVDVDAALAVL 205
>UniRef50_Q0UVR9 Cluster: Putative uncharacterized protein; n=1;
Phaeosphaeria nodorum|Rep: Putative uncharacterized
protein - Phaeosphaeria nodorum (Septoria nodorum)
Length = 288
Score = 105 bits (253), Expect = 1e-21
Identities = 67/167 (40%), Positives = 95/167 (56%), Gaps = 6/167 (3%)
Frame = +3
Query: 363 SILTSNKVVLDVYLG-KDGVVAHAK-KGSLLIDSSTIDPNVPKQIFPIALEKGLG-FTDA 533
SI+ K V VYL K GV+A K +G L+++ STID K++ E+GLG + DA
Sbjct: 27 SIVPGGKDVKTVYLDEKTGVIAARKDEGRLMLECSTIDVESTKEVGRKLKEEGLGTYIDA 86
Query: 534 PVSGGVMGAQNATLAFMAGGRKEDFERSLP-LLKVMG--AKQFHCGQIGSGQVAKLTNNM 704
PVSGGV A+ TL+ + G D LP L ++G +K F+ +G+G AK++NN
Sbjct: 87 PVSGGVPAAEAGTLSMLIGAPPPDPTSLLPSTLSLLGTPSKFFYLHTLGAGLTAKISNNY 146
Query: 705 LMGITGMAXAECMXMGIKMGLXPKVLLDVLNNSSXRSWSTXXVLSXP 845
L G +A AE + +G+K GL P L V+ NS+ +SW VL P
Sbjct: 147 LSGTILLATAEALAIGVKHGLDPAALYSVIKNSTGQSWMCDHVLPIP 193
>UniRef50_UPI00015B4162 Cluster: PREDICTED: similar to MGC108315
protein; n=1; Nasonia vitripennis|Rep: PREDICTED:
similar to MGC108315 protein - Nasonia vitripennis
Length = 276
Score = 104 bits (250), Expect = 3e-21
Identities = 52/122 (42%), Positives = 73/122 (59%)
Frame = +3
Query: 138 LYTAARRAYSSNTDKNVAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGVTP 317
+YT R NV F+GLGNMGGFMA NL+KKG+ + +D +K A++ G
Sbjct: 13 IYTVGR--VGQRDFSNVGFVGLGNMGGFMAKNLLKKGYKLTVFDINKTAIDNVVSAGAKG 70
Query: 318 ANSIXXXXXXXXXXXSILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFP 497
A S+ ++L N+ VLD Y GKDG+++ AKKG+ L+DSSTIDP+V + +F
Sbjct: 71 AESVAEVSQNSEVIVTMLPMNQHVLDTYTGKDGIISSAKKGTFLVDSSTIDPSVSQTVFK 130
Query: 498 IA 503
A
Sbjct: 131 AA 132
Score = 70.9 bits (166), Expect = 4e-11
Identities = 29/60 (48%), Positives = 42/60 (70%)
Frame = +3
Query: 645 KQFHCGQIGSGQVAKLTNNMLMGITGMAXAECMXMGIKMGLXPKVLLDVLNNSSXRSWST 824
K HCG G GQVAK+ NNML+ I+ + +E + +G K+GL PK+L D++N S+ R WS+
Sbjct: 134 KAVHCGDTGMGQVAKICNNMLLAISMIGVSEALSLGEKLGLDPKILTDIVNTSTGRCWSS 193
>UniRef50_A6SUL3 Cluster: 2-hydroxy-3-oxopropionate reductase; n=1;
Janthinobacterium sp. Marseille|Rep:
2-hydroxy-3-oxopropionate reductase - Janthinobacterium
sp. (strain Marseille) (Minibacterium massiliensis)
Length = 304
Score = 104 bits (250), Expect = 3e-21
Identities = 63/196 (32%), Positives = 102/196 (52%)
Frame = +3
Query: 186 VAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGVTPANSIXXXXXXXXXXXS 365
+AFLG+G MG MA+ L++ G+ V ++ ++ + A G + A + +
Sbjct: 10 IAFLGIGLMGKPMASRLLQAGYPVTAWNRTRSKADELAPLGASVAERVADAVAAADIVIT 69
Query: 366 ILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAPVSG 545
+L + +V V D + K G+L+ID S+ + +++ +G+ F DAPVSG
Sbjct: 70 MLEAGPIVAQVI---DAALPGLKHGALVIDMSSTRQSEAQEVHAKLAAQGVRFIDAPVSG 126
Query: 546 GVMGAQNATLAFMAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMGITGM 725
GV+GA+ +LA MAGG +DF + +L VMG G G GQ+AKL N +++G T
Sbjct: 127 GVVGAEAGSLAIMAGGSAQDFAEAEAVLTVMGRPTL-VGPAGCGQIAKLCNQLIVGGTLN 185
Query: 726 AXAECMXMGIKMGLXP 773
AE + + G P
Sbjct: 186 IVAEALLLAQAGGADP 201
>UniRef50_A3WAC4 Cluster: Dehydrogenase; n=4; Bacteria|Rep:
Dehydrogenase - Erythrobacter sp. NAP1
Length = 301
Score = 104 bits (249), Expect = 4e-21
Identities = 64/219 (29%), Positives = 109/219 (49%), Gaps = 6/219 (2%)
Frame = +3
Query: 180 KNVAFLGLGNMGGFMAANLVKKGFTVRGYD----PSKDALNAAAKNG-VTPANS-IXXXX 341
K +AFLGLG MGG M +LV+ G GY+ +++ + G V P S
Sbjct: 5 KRIAFLGLGVMGGPMWGHLVRAGHEATGYNRNFAKAEEWSDRLGDEGLVAPIESDAATAV 64
Query: 342 XXXXXXXSILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLG 521
+ L ++ V V G++GV+A K+G+ ID +++ P + ++I GL
Sbjct: 65 RGKDVVLACLGNDDDVASVLFGENGVLAAMKRGATFIDHTSVSPGLARRIADECERLGLH 124
Query: 522 FTDAPVSGGVMGAQNATLAFMAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNN 701
DAPVSGG GA+N L+ M GG +E + P+++ A+ H G+ G+GQ AK N
Sbjct: 125 AVDAPVSGGQAGAENGKLSIMCGGSEEAMASAQPVMQAYAARIVHIGEAGAGQTAKAINQ 184
Query: 702 MLMGITGMAXAECMXMGIKMGLXPKVLLDVLNNSSXRSW 818
+ + +E + + G+ +++ ++ + +SW
Sbjct: 185 VCIAGVLAGLSEGVRLAQATGVDTYKVVEAISGGAAQSW 223
>UniRef50_Q8VYC5 Cluster: Fructose-bisphosphate aldolase; n=12;
cellular organisms|Rep: Fructose-bisphosphate aldolase -
Arabidopsis thaliana (Mouse-ear cress)
Length = 1373
Score = 104 bits (249), Expect = 4e-21
Identities = 70/214 (32%), Positives = 101/214 (47%), Gaps = 3/214 (1%)
Frame = +3
Query: 186 VAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGVTPANSIXXXXXXXXXXXS 365
+ F+GLG MG MAA+L+K F+V GYD K L G ANS
Sbjct: 324 IGFIGLGAMGFGMAAHLLKSNFSVCGYDVYKPTLVRFENAGGLAANSPAEVTKDVDVLVI 383
Query: 366 ILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKG--LGFTDAPV 539
++T+ DV G G V G+ ++ +ST+ P Q+ +G L DAPV
Sbjct: 384 MVTNEVQAEDVLYGHLGAVEAIPSGATVVLASTVSPAFVSQLERRLENEGKDLKLVDAPV 443
Query: 540 SGGVMGAQNATLAFMAGGRKEDFERSLPLLKVMGAKQFHC-GQIGSGQVAKLTNNMLMGI 716
SGGV A L MA G E + + +L + K + G G+G K+ N +L G+
Sbjct: 444 SGGVKRAAMGELTIMASGTDEALKSAGLVLSALSEKLYVIKGGCGAGSGVKMVNQLLAGV 503
Query: 717 TGMAXAECMXMGIKMGLXPKVLLDVLNNSSXRSW 818
+ AE M G ++GL + L +V++NS SW
Sbjct: 504 HIASAAEAMAFGARLGLNTRKLFNVISNSGGTSW 537
Score = 86.2 bits (204), Expect = 1e-15
Identities = 57/214 (26%), Positives = 105/214 (49%), Gaps = 3/214 (1%)
Frame = +3
Query: 186 VAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGVTPANSIXXXXXXXXXXXS 365
V F+GL + +A++L++ GF V+ ++ S + + + G +S
Sbjct: 5 VGFVGLDSFSFELASSLLRSGFKVQAFEISTELVEKFIELGGHKCDSPADVGKAAAAVVV 64
Query: 366 ILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKG--LGFTDAPV 539
+L+ + DV G +GV+ +K ++L+ SSTI +++ EK + DA V
Sbjct: 65 VLSHPDQIQDVIFGDEGVMKGLQKDAVLLLSSTISTLQLQKLEKQLTEKREQIFVVDAYV 124
Query: 540 SGGVMGAQNATLAFMAGGRKEDFERSLPLLKVMGAKQFHC-GQIGSGQVAKLTNNMLMGI 716
G+ + L +A GR + R+ P L M + G+IG+G K+ N +L GI
Sbjct: 125 LKGMSELLDGKLMIIASGRSDSITRAQPYLTAMCQNLYTFEGEIGAGSKVKMVNELLEGI 184
Query: 717 TGMAXAECMXMGIKMGLXPKVLLDVLNNSSXRSW 818
+A E + +G + G+ P +L D+++N++ SW
Sbjct: 185 HLVAAVEAISLGSQAGVHPWILYDIISNAAGNSW 218
>UniRef50_A1ZWM5 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=1;
Microscilla marina ATCC 23134|Rep: 3-hydroxyisobutyrate
dehydrogenase - Microscilla marina ATCC 23134
Length = 295
Score = 103 bits (248), Expect = 5e-21
Identities = 67/205 (32%), Positives = 99/205 (48%)
Frame = +3
Query: 186 VAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGVTPANSIXXXXXXXXXXXS 365
+AF+GLG MG MA+NL+K + Y+ S A G A++ S
Sbjct: 3 IAFIGLGIMGSRMASNLLKHKVDLTVYNRSLAATTPLVALGAKVAHTTTEAVKEADIVFS 62
Query: 366 ILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAPVSG 545
+L S +VV V G+ G ++ K +L ID STI P A + + F +APV+G
Sbjct: 63 MLASPQVVKAVAYGQTGFLSKMKSKALWIDCSTISPAFALASAQEASKHEVVFVEAPVAG 122
Query: 546 GVMGAQNATLAFMAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMGITGM 725
A+NA L F+ GG ++ P +++MG K H G I K+ N L+ +
Sbjct: 123 TKSHAENAELVFLVGGGTTAIAQATPYMEMMGKKVVHIGAISKASALKILINYLLAQGML 182
Query: 726 AXAECMXMGIKMGLXPKVLLDVLNN 800
A AE + +G K GL + LL+ L N
Sbjct: 183 AFAEALVVGEKQGLDRRFLLEFLPN 207
>UniRef50_Q656T5 Cluster: Oxidoreductase-like; n=3; Oryza
sativa|Rep: Oxidoreductase-like - Oryza sativa subsp.
japonica (Rice)
Length = 341
Score = 103 bits (248), Expect = 5e-21
Identities = 71/253 (28%), Positives = 111/253 (43%)
Frame = +3
Query: 48 LLCARAHGRTLN*EKNKFKMAARTILSTQCLYTAARRAYSSNTDKNVAFLGLGNMGGFMA 227
LLCARA AR + S C +++ + V FLGLG MG MA
Sbjct: 9 LLCARAAAAAPTLRLRGGGRGARLVFS--CSASSSSPSGEGGFSGKVGFLGLGIMGAPMA 66
Query: 228 ANLVKKGFTVRGYDPSKDALNAAAKNGVTPANSIXXXXXXXXXXXSILTSNKVVLDVYLG 407
+NL+ G V ++ ++ + G S ++L + ++V G
Sbjct: 67 SNLINAGCDVTVWNRTRSKCDPLLSLGAKYEPSPADVASSCDVTFAMLADPESAVEVACG 126
Query: 408 KDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAPVSGGVMGAQNATLAFMA 587
+G G +D ST+D K I G F +APVSG A++ L F+
Sbjct: 127 ANGAAQGMAPGKGYVDVSTVDAATSKLIGKHITSTGASFLEAPVSGSKKPAEDGLLIFLT 186
Query: 588 GGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMGITGMAXAECMXMGIKMGL 767
G + + R LL VMG +F G +G G KL NM+MG ++ +E + + K+GL
Sbjct: 187 AGDESLYNRVASLLDVMGKSRFFLGDVGKGADMKLVVNMVMGSMMVSFSEGLLLSEKVGL 246
Query: 768 XPKVLLDVLNNSS 806
P L++V++ +
Sbjct: 247 DPNTLVEVISQGA 259
>UniRef50_Q606G9 Cluster: Oxidoreductase, Gfo/Idh/MocA family; n=6;
Proteobacteria|Rep: Oxidoreductase, Gfo/Idh/MocA family
- Methylococcus capsulatus
Length = 289
Score = 103 bits (247), Expect = 6e-21
Identities = 62/210 (29%), Positives = 104/210 (49%), Gaps = 1/210 (0%)
Frame = +3
Query: 192 FLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGVTPA-NSIXXXXXXXXXXXSI 368
F+GLG MG MA NL + G ++ + + A A TPA ++ +
Sbjct: 5 FVGLGAMGLGMARNLRRAGLLAGVWNRTPEKARAFAAETGTPAWATLTEMAPACDVIVTC 64
Query: 369 LTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAPVSGG 548
++++ VL+V + + G++++D ST+ ++ + + G F DAPVSGG
Sbjct: 65 VSADADVLEVIAA---LTPGLRPGAVIVDCSTVGVATARRAAEVVRQAGGDFLDAPVSGG 121
Query: 549 VMGAQNATLAFMAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMGITGMA 728
V GA++ TLA M GGR E E+ P+L MG++ H G G+GQ K N ++ A
Sbjct: 122 VEGARDGTLALMIGGRAETVEKVRPVLAAMGSRLMHMGDTGAGQATKAVNQVMCAGINQA 181
Query: 729 XAECMXMGIKMGLXPKVLLDVLNNSSXRSW 818
E + G + L ++DV++ + +W
Sbjct: 182 VTEALAFGQALDLDLDKVIDVVSGGAAGNW 211
>UniRef50_Q121N3 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=19;
Burkholderiales|Rep: 3-hydroxyisobutyrate dehydrogenase
- Polaromonas sp. (strain JS666 / ATCC BAA-500)
Length = 298
Score = 103 bits (247), Expect = 6e-21
Identities = 60/213 (28%), Positives = 98/213 (46%), Gaps = 1/213 (0%)
Frame = +3
Query: 183 NVAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGVTPANSIXXXXXXXXXXX 362
NV +GLG MG +A L G+ V YD A+ G +++
Sbjct: 5 NVGVIGLGAMGRGIAQTLRSAGYAVHVYDVRAQAVQEFVAAGGVACDTLTQLAAACEVVV 64
Query: 363 SILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAPVS 542
S++ + DV + GV + K GS+ + ST+DP + G+ + DAP+S
Sbjct: 65 SVVVNAAQTEDVLWSEQGVASAMKSGSVFVMCSTVDPQWSIATEARLDKLGIHYVDAPIS 124
Query: 543 GGVMGAQNATLAFMAGGRKEDFERSLPLLKVMGAKQFHCGQ-IGSGQVAKLTNNMLMGIT 719
GG A + M+ R +E++ +L M K + G G+G K+ N +L G+
Sbjct: 125 GGAAKAAAGQMTVMSSARPAAYEKAGDVLAAMAGKVYRLGDCAGAGSKVKIINQLLAGVH 184
Query: 720 GMAXAECMXMGIKMGLXPKVLLDVLNNSSXRSW 818
A AE M +G++ G+ P L +V+ +S+ SW
Sbjct: 185 IAAAAEAMALGLREGVDPNALYEVITHSAGNSW 217
>UniRef50_A7IE35 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=2;
Proteobacteria|Rep: 3-hydroxyisobutyrate dehydrogenase -
Xanthobacter sp. (strain Py2)
Length = 330
Score = 103 bits (247), Expect = 6e-21
Identities = 61/211 (28%), Positives = 97/211 (45%), Gaps = 1/211 (0%)
Frame = +3
Query: 189 AFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGVTPANSIXXXXXXXXXXXSI 368
A +GLG+MG MA +L + GF V G+D + A+ A G A+S S+
Sbjct: 36 AVIGLGSMGYGMAQSLKRAGFDVAGFDVNAAAVERFAAEGGRGASSPAEAARDADVVVSV 95
Query: 369 LTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAPVSGG 548
+ + + G DGV G++ + S+T+DP + + + G + DAP+SGG
Sbjct: 96 VVNAAQTETILFGADGVAQTLADGAVFLSSATMDPEIARTLAARLEATGRLYLDAPISGG 155
Query: 549 VMGAQNATLAFMAGGRKEDFERSLPLLKVMGAKQFHCGQI-GSGQVAKLTNNMLMGITGM 725
A L +A G F ++ P L M AK + G G G K+ N +L G+
Sbjct: 156 AQRAAEGALTILASGSPAAFAKARPALDAMAAKLYELGDAPGQGAAFKMINQLLAGVHIA 215
Query: 726 AXAECMXMGIKMGLXPKVLLDVLNNSSXRSW 818
A +E + + GL + +V+ S+ SW
Sbjct: 216 AASEAVAFAARQGLDIAKVYEVITASAGNSW 246
>UniRef50_Q9L7S0 Cluster: Uncharacterized oxidoreductase yihU; n=24;
Gammaproteobacteria|Rep: Uncharacterized oxidoreductase
yihU - Salmonella typhimurium
Length = 298
Score = 103 bits (247), Expect = 6e-21
Identities = 64/207 (30%), Positives = 96/207 (46%)
Frame = +3
Query: 186 VAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGVTPANSIXXXXXXXXXXXS 365
+AF+GLG MG MA+NL+K+G + +D + DA+ G PA+S +
Sbjct: 4 IAFIGLGQMGSPMASNLLKQGHQLSVFDVNPDAVQRLVDKGAQPASSPAQATIGAEFVIT 63
Query: 366 ILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAPVSG 545
+L + +V V G+ GV + +L+ID STI P + KG D P+
Sbjct: 64 MLPNGDLVRSVLFGEQGVCETLSREALVIDMSTIHPLQTDNLIADMQSKGFSMMDVPIGR 123
Query: 546 GVMGAQNATLAFMAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMGITGM 725
A TL +AGG E ER+ P+L MG + + G G G KL NN +
Sbjct: 124 TSDNAITGTLLLLAGGTAEQVERATPVLMAMGNELVNTGGPGMGIRVKLINNYMSIALNA 183
Query: 726 AXAECMXMGIKMGLXPKVLLDVLNNSS 806
AE + +GL V L V++ ++
Sbjct: 184 LSAEAAVLCEALGLSFDVALKVMSGTA 210
>UniRef50_A3JU55 Cluster: Predicted dehydrogenase, with
NAD(P)-binding Rossmann-fold domain; n=2; Bacteria|Rep:
Predicted dehydrogenase, with NAD(P)-binding
Rossmann-fold domain - Rhodobacterales bacterium
HTCC2150
Length = 302
Score = 102 bits (245), Expect = 1e-20
Identities = 64/205 (31%), Positives = 97/205 (47%), Gaps = 1/205 (0%)
Frame = +3
Query: 195 LGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGVTPANSIXXXXXXXXXXXSILT 374
+GLG+MG +A NL+K GF G D + + A + G A + ++
Sbjct: 6 IGLGDMGSGLAKNLLKAGFETTGIDMKPERMAAFVEMGGRAAVDVADVGANADAVFVMVM 65
Query: 375 SNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAPVSGGVM 554
+ V V G+ G++AH KG +I S+TI P ++I + G+ D PVSGG
Sbjct: 66 NGDQVKSVLFGEGGLLAHMPKGGAVILSATIKPVEAEEIGAAMADSGIHLIDTPVSGGFP 125
Query: 555 GAQNATLAFMAGGRKEDFERSLPLLKVMGAKQFHCG-QIGSGQVAKLTNNMLMGITGMAX 731
GAQ TL MA G E + P+++ + A + G + G GQ K L+G A
Sbjct: 126 GAQGGTLTMMAAGVDEVLDTYAPVMEAVSATIWCVGTEAGQGQTVKACLQSLLGAMFSAT 185
Query: 732 AECMXMGIKMGLXPKVLLDVLNNSS 806
E + K G+ +V +V+ NSS
Sbjct: 186 FEASVLAAKAGINGEVFHNVVANSS 210
>UniRef50_A5VBF0 Cluster: 2-hydroxy-3-oxopropionate reductase
precursor; n=1; Sphingomonas wittichii RW1|Rep:
2-hydroxy-3-oxopropionate reductase precursor -
Sphingomonas wittichii RW1
Length = 298
Score = 102 bits (244), Expect = 1e-20
Identities = 65/197 (32%), Positives = 94/197 (47%), Gaps = 1/197 (0%)
Frame = +3
Query: 180 KNVAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGVTPANSIXXXXXXXXXX 359
+ +AFLG+G MG MAA L+ G + ++ S D L G
Sbjct: 3 QRMAFLGIGLMGRPMAARLLDSGHELALWNRSADKLAPLVAAGGRACAIPAEAVEGAAVV 62
Query: 360 XSILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKG-LGFTDAP 536
LT V V G+ G G+L++D STI P+ + E G + D P
Sbjct: 63 CLCLTDADAVEQVMFGEGGAARALAPGALVVDFSTIGPDATRGFAKRLAETGDAQWLDCP 122
Query: 537 VSGGVMGAQNATLAFMAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMGI 716
VSGGV GA+ TLA +AGG +R PLL ++ A+ G +G+GQ AKL N +++
Sbjct: 123 VSGGVAGAEAGTLAILAGGDAAAIDRVRPLLALLSARVTRMGGVGAGQAAKLCNQLIVAT 182
Query: 717 TGMAXAECMXMGIKMGL 767
+A AE M +G +G+
Sbjct: 183 NMLAIAEAMHVGEALGI 199
>UniRef50_A3X9R7 Cluster: 3-hydroxyisobutyrate dehydrogenase family
protein; n=2; Rhodobacterales|Rep: 3-hydroxyisobutyrate
dehydrogenase family protein - Roseobacter sp. MED193
Length = 300
Score = 102 bits (244), Expect = 1e-20
Identities = 62/210 (29%), Positives = 101/210 (48%)
Frame = +3
Query: 186 VAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGVTPANSIXXXXXXXXXXXS 365
+ +GLG MGG + L+ + + +D +A AA G A+S+ S
Sbjct: 17 IGLVGLGAMGGGYLSRLMAQNCDLMCFDAMPEARARAAAAGAKVADSLADFSACDTVILS 76
Query: 366 ILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAPVSG 545
+ ++ + + G + KKGS+++D+ST +P+ K++ A G F D PVSG
Sbjct: 77 L--PKAAIVSAVMEELG--PYLKKGSIVVDTSTSEPDTTKRLAAAAESNGYTFLDGPVSG 132
Query: 546 GVMGAQNATLAFMAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMGITGM 725
G +GA+ T+ + GG + F + PLL+ M K H G G+G K+ NN+L +
Sbjct: 133 GPLGARTGTMTMVVGGDEAGFTKVRPLLEKMTGKLVHIGPSGAGHTVKIANNLLCAANLV 192
Query: 726 AXAECMXMGIKMGLXPKVLLDVLNNSSXRS 815
+E M + G+ LL +N S RS
Sbjct: 193 LMSEMAQMAERAGISLTELLTGINAGSGRS 222
>UniRef50_A7PEG7 Cluster: Chromosome chr11 scaffold_13, whole genome
shotgun sequence; n=2; Vitis vinifera|Rep: Chromosome
chr11 scaffold_13, whole genome shotgun sequence - Vitis
vinifera (Grape)
Length = 348
Score = 102 bits (244), Expect = 1e-20
Identities = 73/227 (32%), Positives = 108/227 (47%), Gaps = 1/227 (0%)
Frame = +3
Query: 144 TAARRAYSSNTDKNVAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGVTPAN 323
TAA S ++ V ++G G MG M A+L+K G+TV ++ + G A+
Sbjct: 37 TAAVAEPVSPSNTRVGWIGTGVMGRSMCAHLMKAGYTVTIFNRTISKAQPLLDMGAHHAS 96
Query: 324 SIXXXXXXXXXXXSILTSNKVVLDVYLG-KDGVVAHAKKGSLLIDSSTIDPNVPKQIFPI 500
S SI+ V V L G ++ + G +L+D +T DP++ +I
Sbjct: 97 SPLALASQSDVVFSIVGFPSDVRSVLLDPSSGALSGLRPGGVLVDMTTSDPSLAAEIASS 156
Query: 501 ALEKGLGFTDAPVSGGVMGAQNATLAFMAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQ 680
A +G DAPVSGG GA+NATLA AGG + R PL +G K + G G GQ
Sbjct: 157 AASRGCFSVDAPVSGGDRGAKNATLAIFAGGDESVVRRLNPLFSHLG-KVNYMGGPGKGQ 215
Query: 681 VAKLTNNMLMGITGMAXAECMXMGIKMGLXPKVLLDVLNNSSXRSWS 821
AKL N +++ T + E M K GL + L+ ++ + S S
Sbjct: 216 YAKLANQIIIASTMLGLIEGMMYAYKSGLDVALFLNAISTGAAGSKS 262
>UniRef50_A0JXR2 Cluster: 2-hydroxy-3-oxopropionate reductase; n=2;
Arthrobacter|Rep: 2-hydroxy-3-oxopropionate reductase -
Arthrobacter sp. (strain FB24)
Length = 333
Score = 101 bits (243), Expect = 2e-20
Identities = 69/210 (32%), Positives = 102/210 (48%), Gaps = 5/210 (2%)
Frame = +3
Query: 180 KNVAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGVTPANSIXXXXXXXXXX 359
K F+GLG MGG MAANL+K G+ V G++ S AL+ A G A +
Sbjct: 16 KRAGFVGLGLMGGPMAANLLKAGWNVTGWNRSAAALDDLAARGGMRAADVASLRDEPVII 75
Query: 360 XSILTSNKVVLDVYLGKDGVVAHAKKG--SLLIDSSTIDPNVPKQ--IFPIALEKGLGFT 527
+L + D G A G ++++ S++ P + + A +G
Sbjct: 76 F-MLPDLSYIEDAAAGLLAGWADEPPGPGTVVVVMSSVSPAAVRDFGVKVSAASRGNAVV 134
Query: 528 -DAPVSGGVMGAQNATLAFMAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNM 704
DAPVSGG GA++ TLA M G ++DF+R LPL MG G +GSG +AK N +
Sbjct: 135 VDAPVSGGTKGAEDGTLAIMVGAGEQDFQRLLPLFNAMGGTVRRLGPLGSGSLAKACNQL 194
Query: 705 LMGITGMAXAECMXMGIKMGLXPKVLLDVL 794
++G T A AE + + G+ L ++L
Sbjct: 195 IVGTTTAALAEAAELAERSGMDVAALYELL 224
>UniRef50_Q8UBW3 Cluster: Oxidoredutase; n=1; Agrobacterium
tumefaciens str. C58|Rep: Oxidoredutase - Agrobacterium
tumefaciens (strain C58 / ATCC 33970)
Length = 300
Score = 101 bits (242), Expect = 3e-20
Identities = 67/190 (35%), Positives = 99/190 (52%)
Frame = +3
Query: 180 KNVAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGVTPANSIXXXXXXXXXX 359
++VAF+G G MGG MA L+ GF+V+ ++ S D A +G A S
Sbjct: 10 RSVAFIGTGLMGGPMARRLLGTGFSVKVWNRSVDKAQALVADGAVLAASPAEAARGADIV 69
Query: 360 XSILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAPV 539
++L+ V +V L + GV KG+++IDSS+I P + ++ G+ DAPV
Sbjct: 70 ITMLSDGNAVGEV-LFEAGVAEALAKGAVVIDSSSIAPPIAREHSSRLQAMGIHHVDAPV 128
Query: 540 SGGVMGAQNATLAFMAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMGIT 719
SGGV GA TLA MAGG + + + MG + + G G+GQ+ KL N ++ IT
Sbjct: 129 SGGVPGATAGTLAIMAGGDEALISGLVDVFAPMG-RLTYVGPSGAGQLCKLANQQIVAIT 187
Query: 720 GMAXAECMXM 749
A AE M +
Sbjct: 188 IGAVAEAMML 197
>UniRef50_Q1IQE6 Cluster: 2-hydroxy-3-oxopropionate reductase
precursor; n=1; Acidobacteria bacterium Ellin345|Rep:
2-hydroxy-3-oxopropionate reductase precursor -
Acidobacteria bacterium (strain Ellin345)
Length = 282
Score = 101 bits (241), Expect = 3e-20
Identities = 66/211 (31%), Positives = 104/211 (49%), Gaps = 1/211 (0%)
Frame = +3
Query: 186 VAFLGLGNMGGFMAANLVKKGFTVRGYDPS-KDALNAAAKNGVTPANSIXXXXXXXXXXX 362
VAFLGLG MG MAANL K G V ++ + KD A TPA +
Sbjct: 3 VAFLGLGIMGRPMAANLAKAGNEVTVWNRTPKDVEGAHVAK--TPAEAAKHADVVWMC-- 58
Query: 363 SILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAPVS 542
++ V V G GV + G +++DSSTI P + KG + DAP++
Sbjct: 59 --VSDTNAVERVLFGDGGVEPVLRAGMVVVDSSTISPVETLKFAERVRAKGADYIDAPIT 116
Query: 543 GGVMGAQNATLAFMAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMGITG 722
G +GA++A L FM G + E ++ PL MG K H G++G GQ +K++ N+ +
Sbjct: 117 GSKIGAESAQLIFMVGAKDETLKKLEPLFLQMGKKIVHMGEVGKGQASKISLNLQIACIY 176
Query: 723 MAXAECMXMGIKMGLXPKVLLDVLNNSSXRS 815
E + ++G+ P+ ++++ ++ RS
Sbjct: 177 EGFIEGFKVATQLGVNPEKFVELVQSTMVRS 207
>UniRef50_A7DSF1 Cluster: 2-hydroxy-3-oxopropionate reductase; n=1;
Candidatus Nitrosopumilus maritimus SCM1|Rep:
2-hydroxy-3-oxopropionate reductase - Candidatus
Nitrosopumilus maritimus SCM1
Length = 292
Score = 101 bits (241), Expect = 3e-20
Identities = 60/208 (28%), Positives = 99/208 (47%)
Frame = +3
Query: 180 KNVAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGVTPANSIXXXXXXXXXX 359
K + +GLG +G + +L++ GF V ++ SKD A + G T +S
Sbjct: 2 KKIGIVGLGMLGNAVGLHLLESGFEVTVFNRSKDKTIQAKEKGATVVDSPKEVAEKSDLV 61
Query: 360 XSILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAPV 539
++ V +V ++G++ K ++ D STIDP+ K I LE G+ D PV
Sbjct: 62 IIVVKDADAVKEVSFEREGIIKSENKKLIVADMSTIDPSESKNISDKFLEFGIHKLDIPV 121
Query: 540 SGGVMGAQNATLAFMAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMGIT 719
GG A L MA G KE FE + + + K F G+ G KL N+ + +
Sbjct: 122 MGGPNVAITGDLVMMASGNKESFEECKKVFEKIANKVFFLGEKGVAHSIKLAMNLQITML 181
Query: 720 GMAXAECMXMGIKMGLXPKVLLDVLNNS 803
+A +E + + K + PK+ L++LN++
Sbjct: 182 ALALSEGITLVKKADVDPKIFLEILNST 209
>UniRef50_Q0RCX7 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=1;
Frankia alni ACN14a|Rep: 3-hydroxyisobutyrate
dehydrogenase - Frankia alni (strain ACN14a)
Length = 313
Score = 100 bits (240), Expect = 4e-20
Identities = 65/213 (30%), Positives = 98/213 (46%), Gaps = 2/213 (0%)
Frame = +3
Query: 186 VAFLGLGNMGGFMAANLVKKGFTVRGYDPSKD--ALNAAAKNGVTPANSIXXXXXXXXXX 359
V F+GLG MG MA +L + GF Y+ ++ A +A + G A
Sbjct: 3 VGFVGLGTMGFPMAGHLARAGFDTVVYNRTETTAARWSAVQRGRVAATPAQAAAGSDVVC 62
Query: 360 XSILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAPV 539
+ + V V LG DG + G+ ++D +T + +I A E G+GF DAPV
Sbjct: 63 VCVGADDDV-RSVLLGPDGALGALAPGATIVDHTTTSAELAVEIAARAAEVGVGFVDAPV 121
Query: 540 SGGVMGAQNATLAFMAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMGIT 719
SGG GA+ L+ M GG + ER P+L GA G +G+GQ+ K+ N +L+
Sbjct: 122 SGGQAGAEAGRLSVMCGGEVDTVERVRPVLAAYGATITRIGPVGTGQLTKMVNQILVAGA 181
Query: 720 GMAXAECMXMGIKMGLXPKVLLDVLNNSSXRSW 818
AE + GL +L ++ + SW
Sbjct: 182 IEGAAEALNFAAAAGLDLDQVLPAVSGGAASSW 214
>UniRef50_A1R2J4 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=1;
Arthrobacter aurescens TC1|Rep: 3-hydroxyisobutyrate
dehydrogenase - Arthrobacter aurescens (strain TC1)
Length = 332
Score = 100 bits (240), Expect = 4e-20
Identities = 68/212 (32%), Positives = 94/212 (44%), Gaps = 2/212 (0%)
Frame = +3
Query: 186 VAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGVTPANSIXXXXXXXXXXXS 365
+ F+GLGNMG M NL GF + D K++ NG A +
Sbjct: 26 IGFIGLGNMGSGMTRNLQAAGFHLVVNDVRKESAAELLANGAEWAEDAAAVAAGSDVVIT 85
Query: 366 ILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAPVSG 545
+L + K V V +G G++A G +D ST P V ++ +G+ DAPVSG
Sbjct: 86 MLPTPKHVETVAMGPGGILAGMPDGGTWVDMSTSVPEVANRVREAGSVRGIRVLDAPVSG 145
Query: 546 GVMGAQNATLAFMAGGRKEDFERSLPLLKVMGAKQ--FHCGQIGSGQVAKLTNNMLMGIT 719
+GA N L GG D ER P+ + MG + H G G+G KL N L
Sbjct: 146 MSVGAANGMLQIFVGGEPADVERLRPVFEAMGDPERILHVGGHGAGYAVKLMINQLWFSH 205
Query: 720 GMAXAECMXMGIKMGLXPKVLLDVLNNSSXRS 815
+A AE + G+K G+ +VL L S S
Sbjct: 206 LVATAEVLSTGVKAGVDLEVLRQALIASPANS 237
>UniRef50_Q47AR2 Cluster: NADP oxidoreductase, coenzyme
F420-dependent:6-phosphogluconate dehydrogenase,
NAD-binding; n=1; Dechloromonas aromatica RCB|Rep: NADP
oxidoreductase, coenzyme
F420-dependent:6-phosphogluconate dehydrogenase,
NAD-binding - Dechloromonas aromatica (strain RCB)
Length = 287
Score = 99 bits (238), Expect = 8e-20
Identities = 67/198 (33%), Positives = 97/198 (48%), Gaps = 4/198 (2%)
Frame = +3
Query: 186 VAFLGLGNMGGFMAANLVKKGFTV----RGYDPSKDALNAAAKNGVTPANSIXXXXXXXX 353
+ F+GLG MG MA NL+K G V R + + L+A AK +PA +
Sbjct: 3 IGFIGLGIMGRPMALNLIKGGHQVTVWARRAESMQPLLDAGAKGAASPAEAARGNELVI- 61
Query: 354 XXXSILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDA 533
S++ V +V G V + + G + +D STI P ++I G+ F DA
Sbjct: 62 ---SMVADAPDVAEVMRG---VASAGESGLVAVDMSTIAPAAARRIGEDLAAAGIDFIDA 115
Query: 534 PVSGGVMGAQNATLAFMAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMG 713
PVSGG +GA +L+ MAGG F ++ P + MG H G G+GQVAK N ++ G
Sbjct: 116 PVSGGEVGAIAGSLSIMAGGSDAAFAKAKPAFECMGKNIVHVGASGAGQVAKAANQIVTG 175
Query: 714 ITGMAXAECMXMGIKMGL 767
+ +A AE K G+
Sbjct: 176 MGVLAVAEAFAFAAKNGV 193
>UniRef50_Q39FA8 Cluster: 2-hydroxy-3-oxopropionate reductase; n=22;
Burkholderiales|Rep: 2-hydroxy-3-oxopropionate reductase
- Burkholderia sp. (strain 383) (Burkholderia cepacia
(strain ATCC 17760/ NCIB 9086 / R18194))
Length = 287
Score = 99 bits (238), Expect = 8e-20
Identities = 63/198 (31%), Positives = 94/198 (47%), Gaps = 3/198 (1%)
Frame = +3
Query: 210 MGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGVTPANSIXXXXXXXXXXXSILTSNKVV 389
MG M +L+ G V ++ S+D A K+G + + + V
Sbjct: 1 MGAPMIRHLLAAGHRVSVWNRSRDKAEALVKDGAQVVGTPRELAERVDTVFVCVLDGRAV 60
Query: 390 LDVYLGKDGVV---AHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAPVSGGVMGA 560
DV G+ G++ A A++ ++D S+I P + A G+G+ DAPVSGGV GA
Sbjct: 61 GDVVFGEHGLLSGDAAARRLQRIVDHSSIPPAATRDYAARATALGVGWVDAPVSGGVPGA 120
Query: 561 QNATLAFMAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMGITGMAXAEC 740
Q TLA MAGGR D + PL+ ++ H G G+GQ AKL N ++ T A AE
Sbjct: 121 QAGTLAVMAGGRAADLDAVRPLIDTYASRITHMGDAGAGQTAKLCNQAIVTATVTAIAEA 180
Query: 741 MXMGIKMGLXPKVLLDVL 794
+ + G+ L + L
Sbjct: 181 VGLAQASGIDAARLAEAL 198
>UniRef50_Q1N6I0 Cluster: Putative oxidoreductase protein; n=1;
Oceanobacter sp. RED65|Rep: Putative oxidoreductase
protein - Oceanobacter sp. RED65
Length = 289
Score = 99 bits (238), Expect = 8e-20
Identities = 63/214 (29%), Positives = 106/214 (49%), Gaps = 2/214 (0%)
Frame = +3
Query: 183 NVAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKN--GVTPANSIXXXXXXXXX 356
N++F+GLG MG MA +LV+ + ++ S +N T ANS+
Sbjct: 2 NISFIGLGKMGYPMAKHLVQANHQLEVFNRSPSKSEDFKRNFEQCTIANSLTDCGKHSEI 61
Query: 357 XXSILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAP 536
+ +++ V + GKD + ++ K G+L+ID +T + ++ LEK + + DAP
Sbjct: 62 IILCIGNDEDVRNTLTGKDSLYSNLKPGTLVIDHTTTSAELACEMQAKLLEKQVDYVDAP 121
Query: 537 VSGGVMGAQNATLAFMAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMGI 716
VSGG GA + L M GG+ ER+ + + H G IGSGQ+ K+ N + +
Sbjct: 122 VSGGEQGAISGQLTIMCGGQALAAERAQGITQAYSKSFTHMGPIGSGQLTKMVNQICVAG 181
Query: 717 TGMAXAECMXMGIKMGLXPKVLLDVLNNSSXRSW 818
A AE + G + GL + ++ V+ + + SW
Sbjct: 182 LIEALAEGIHFGQQAGLDMEKVMKVVGSGAASSW 215
>UniRef50_A1WJN2 Cluster: 6-phosphogluconate dehydrogenase,
NAD-binding; n=3; Proteobacteria|Rep: 6-phosphogluconate
dehydrogenase, NAD-binding - Verminephrobacter eiseniae
(strain EF01-2)
Length = 297
Score = 99 bits (238), Expect = 8e-20
Identities = 67/213 (31%), Positives = 99/213 (46%), Gaps = 1/213 (0%)
Frame = +3
Query: 186 VAFLGLGNMGGFMAANLVKK-GFTVRGYDPSKDALNAAAKNGVTPANSIXXXXXXXXXXX 362
+ F+GLG MG + NL +K G V +D L A +GV S
Sbjct: 9 IGFIGLGVMGEPICRNLARKSGAQVLAFDLDAAPLQRLAADGVQGQGSASAVMAQSDTVF 68
Query: 363 SILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAPVS 542
L S +V + +DG++A A+ G +++D T + +Q+ + F DAPV+
Sbjct: 69 LSLPSGAIVAQLCRQQDGLLASARPGHIVVDLGTSSVDGTRQLAAEFAARQAKFADAPVA 128
Query: 543 GGVMGAQNATLAFMAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMGITG 722
AQ TLA M G E F PL+ + CG +G GQV K+ NNM++ T
Sbjct: 129 RTRAAAQAGTLAVMVGADPELFGVIEPLIATFASDIALCGPVGCGQVLKILNNMILFETV 188
Query: 723 MAXAECMXMGIKMGLXPKVLLDVLNNSSXRSWS 821
+A +E +G K G+ VL D L N S S++
Sbjct: 189 VAISEAKAIGEKAGVDASVLFDTLANGSADSFA 221
>UniRef50_Q8PK98 Cluster: 3-hydroxyisobutirate dehydrogenase; n=3;
Proteobacteria|Rep: 3-hydroxyisobutirate dehydrogenase -
Xanthomonas axonopodis pv. citri
Length = 300
Score = 99.5 bits (237), Expect = 1e-19
Identities = 65/217 (29%), Positives = 95/217 (43%), Gaps = 3/217 (1%)
Frame = +3
Query: 183 NVAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGVTPANSIXXXXXXXXXXX 362
++ +G+GN+G A + +G V +D AL A + G T A +
Sbjct: 2 DIGLVGMGNIGRHFVARWLAQGHRVIVHDTRAQALQQAKEAGATTAAGMADVLANAEVIA 61
Query: 363 SILTSNKVVLDVY--LGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAP 536
L VVL+V L + L++D ST ++ + + F AP
Sbjct: 62 LSLPLPSVVLEVARTLAAAAAATEMRDSLLVVDLSTTGAQTTSEVGHLLERADVSFLSAP 121
Query: 537 VSGGVMGAQNATLAFMAGGRKEDFERSLPLLKVMGAKQFHC-GQIGSGQVAKLTNNMLMG 713
VSGG A L MA G +ER+ PLL +G F+ G + GQ KL NN L
Sbjct: 122 VSGGTAAAAQGVLTVMAAGPLAAYERARPLLDAVGRHIFYLGGDVRLGQTLKLINNTLYA 181
Query: 714 ITGMAXAECMXMGIKMGLXPKVLLDVLNNSSXRSWST 824
+A E + G K GL + +LDV+N SS R ++T
Sbjct: 182 SAMLASCEALVCGAKAGLDARTMLDVINRSSGRCFAT 218
>UniRef50_A1UJF2 Cluster: 6-phosphogluconate dehydrogenase,
NAD-binding; n=6; Actinomycetales|Rep:
6-phosphogluconate dehydrogenase, NAD-binding -
Mycobacterium sp. (strain KMS)
Length = 272
Score = 99.5 bits (237), Expect = 1e-19
Identities = 60/210 (28%), Positives = 95/210 (45%)
Frame = +3
Query: 186 VAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGVTPANSIXXXXXXXXXXXS 365
V F+GLG+ GG MA +V+ G+ + + +L A A S
Sbjct: 3 VGFIGLGSQGGPMARRIVEGGYELTLWARRPASLEPYADTAAKTAGSPAELAAASDLVCV 62
Query: 366 ILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAPVSG 545
+ + V +V G GV+A G+++ ST+ P+ ++I A + + DAPVSG
Sbjct: 63 CVVGDDDVREVLYGDTGVLAGLAPGAMIAIHSTVHPDTCREIAEKAAAQNVSVIDAPVSG 122
Query: 546 GVMGAQNATLAFMAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMGITGM 725
G + L M GG + D E++ P+ H G +GSGQV K+ NN+L
Sbjct: 123 GAPAVEQGKLLVMVGGEEADVEKARPVFATYADPIVHLGPLGSGQVTKILNNLLFTANLG 182
Query: 726 AXAECMXMGIKMGLXPKVLLDVLNNSSXRS 815
+ + +G +G+ L +VLN S S
Sbjct: 183 SALSTLELGESLGIPRTQLAEVLNGGSATS 212
>UniRef50_A3WMG5 Cluster: Probable 3-hydroxyisobutyrate
dehydrogenase; n=1; Idiomarina baltica OS145|Rep:
Probable 3-hydroxyisobutyrate dehydrogenase - Idiomarina
baltica OS145
Length = 284
Score = 98.7 bits (235), Expect = 2e-19
Identities = 61/207 (29%), Positives = 104/207 (50%), Gaps = 1/207 (0%)
Frame = +3
Query: 186 VAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGVTPANSIXXXXXXXXXXXS 365
+AFLGLG MG MA +L+ G ++ ++ ++ + G A++ +
Sbjct: 4 IAFLGLGAMGIRMAQHLIDAGHSLTVWNRTESRAEPLLEQGAQWADTPAEAAQGAELVIA 63
Query: 366 ILTSNKVVLDVYLGKD-GVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAPVS 542
++ + V+L + G ++ I+SST+ + K++ A ++G +APVS
Sbjct: 64 MVRDDDASAAVWLDEQTGAFKGMSDNAIAIESSTLSVDWVKELAQQAQQRGKQLIEAPVS 123
Query: 543 GGVMGAQNATLAFMAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMGITG 722
G AQNA L ++ GG R+ P+L +MG K H G++GSG +AKL N LMGI
Sbjct: 124 GSRPQAQNAELVYLVGGDAHLVNRAEPVLSLMGKKVNHTGEMGSGALAKLVTNTLMGIQV 183
Query: 723 MAXAECMXMGIKMGLXPKVLLDVLNNS 803
AE + M + G P +L+ ++ +
Sbjct: 184 TTIAELIGMLKRQGQDPDAILEAVSTT 210
>UniRef50_Q830A7 Cluster: 2-hydroxy-3-oxopropionate reductase; n=7;
Firmicutes|Rep: 2-hydroxy-3-oxopropionate reductase -
Enterococcus faecalis (Streptococcus faecalis)
Length = 296
Score = 98.3 bits (234), Expect = 2e-19
Identities = 57/212 (26%), Positives = 96/212 (45%)
Frame = +3
Query: 186 VAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGVTPANSIXXXXXXXXXXXS 365
+ F+G G MG + N++K +V Y+ +K + G ++ +
Sbjct: 4 IGFIGTGVMGKSIIRNMMKNNLSVNVYNRTKSKTDDLVAEGAVWYDTPKAIAEASDIIFT 63
Query: 366 ILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAPVSG 545
++ V VY + G+ G +++D +T P + ++I A E G DAPVSG
Sbjct: 64 MVGFPSDVEGVYFNETGIFQADLTGKIVVDLTTSTPTLAEKIAKKAAEVGAHALDAPVSG 123
Query: 546 GVMGAQNATLAFMAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMGITGM 725
G +GA+N TL M GG +E ++ LP+ K G G G GQ K+ N +++ T
Sbjct: 124 GDLGAKNGTLTIMVGGDQESYDTVLPIFKTFGKTFMLHGSAGKGQHTKMANQLMIAGTMT 183
Query: 726 AXAECMXMGIKMGLXPKVLLDVLNNSSXRSWS 821
E + GL + +L+ + S +WS
Sbjct: 184 GLTEMLVYANATGLTLEKVLETVGGGSAANWS 215
>UniRef50_Q0FFH2 Cluster: Putative 2-hydroxyacid dehydrogenase; n=2;
Alphaproteobacteria|Rep: Putative 2-hydroxyacid
dehydrogenase - alpha proteobacterium HTCC2255
Length = 303
Score = 98.3 bits (234), Expect = 2e-19
Identities = 57/211 (27%), Positives = 99/211 (46%)
Frame = +3
Query: 186 VAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGVTPANSIXXXXXXXXXXXS 365
+ F+GLG MGG + NL++ G + D + G A++ +
Sbjct: 3 IGFIGLGTMGGAASLNLIRGGHQLTVCDLDLKRATKHLELGAKWADTPSEAAKDVDIVFT 62
Query: 366 ILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAPVSG 545
++ K + + G++G++ G + +D +T P + +++ ++ G DAPV+G
Sbjct: 63 MVFGPKQIEQIIRGENGLLHSMGPGQVWVDLTTNQPELARELAQEIIDTGAIAIDAPVTG 122
Query: 546 GVMGAQNATLAFMAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMGITGM 725
V GA+N + AGG KE ER P++++MG + G GSG + KL +N L I
Sbjct: 123 AVDGARNGNMTQFAGGDKETIERIRPVMELMGPVHY-MGSNGSGSITKLASNQLWAIHAT 181
Query: 726 AXAECMXMGIKMGLXPKVLLDVLNNSSXRSW 818
A E + M +K G+ + L + SW
Sbjct: 182 AMGEALVMAVKSGVELSRAWEALKIGASESW 212
>UniRef50_A6EH53 Cluster: Putative uncharacterized protein; n=1;
Pedobacter sp. BAL39|Rep: Putative uncharacterized
protein - Pedobacter sp. BAL39
Length = 292
Score = 98.3 bits (234), Expect = 2e-19
Identities = 57/205 (27%), Positives = 96/205 (46%)
Frame = +3
Query: 192 FLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGVTPANSIXXXXXXXXXXXSIL 371
++GLGNMG MA ++ KG+++ Y+ + G A + ++
Sbjct: 17 WIGLGNMGVPMAGQVLNKGYSLTVYNRTLSKTEPLVAQGAKVAGTPGELIAATDIVFLMV 76
Query: 372 TSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAPVSGGV 551
+ + V ++ G DG+++ G ++++ ST+ P + ++ G+ + DAPVSG V
Sbjct: 77 SDDHAVASLFEGADGLLSKELHGKVIVNMSTVSPAISIKMAAACSAVGIEYLDAPVSGSV 136
Query: 552 MGAQNATLAFMAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMGITGMAX 731
A + L M GG ++ F + PLL MG H G G G AKL N L+ I
Sbjct: 137 KQATDGQLVIMVGGEEQAFHAAEPLLSCMGKLVMHLGASGIGNKAKLAINTLLAIYTEGL 196
Query: 732 AECMXMGIKMGLXPKVLLDVLNNSS 806
AE + K + + LL +L N +
Sbjct: 197 AEIVTFSRKHQINTEDLLTLLGNGA 221
>UniRef50_Q49A26 Cluster: Cytokine-like nuclear factor n-pac; n=46;
Euteleostomi|Rep: Cytokine-like nuclear factor n-pac -
Homo sapiens (Human)
Length = 553
Score = 98.3 bits (234), Expect = 2e-19
Identities = 60/230 (26%), Positives = 102/230 (44%)
Frame = +3
Query: 126 STQCLYTAARRAYSSNTDKNVAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKN 305
S Q + A + TDK + FLGLG MG + +NL+K G TV ++ + + + +
Sbjct: 250 SIQAADSTAVNGSITPTDKKIGFLGLGLMGSGIVSNLLKMGHTVTVWNRTAEKCDLFIQE 309
Query: 306 GVTPANSIXXXXXXXXXXXSILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPK 485
G + + ++ K D+ LG GV+ + G +D ST+D +
Sbjct: 310 GARLGRTPAEVVSTCDITFACVSDPKAAKDLVLGPSGVLQGIRPGKCYVDMSTVDADTVT 369
Query: 486 QIFPIALEKGLGFTDAPVSGGVMGAQNATLAFMAGGRKEDFERSLPLLKVMGAKQFHCGQ 665
++ + + +G F +APVSG + + L +A G + +E + MG F G+
Sbjct: 370 ELAQVIVSRGGRFLEAPVSGNQQLSNDGMLVILAAGDRGLYEDCSSCFQTMGKTSFFLGE 429
Query: 666 IGSGQVAKLTNNMLMGITGMAXAECMXMGIKMGLXPKVLLDVLNNSSXRS 815
+G+ L NM+ G AE + + G + LLD+LN S
Sbjct: 430 VGNAAKMMLIVNMVQGSFMATIAEGLTLAQVTGRSQQTLLDILNQGQLAS 479
>UniRef50_Q73P00 Cluster: 3-hydroxyacid dehydrogenase family
protein; n=4; Bacteria|Rep: 3-hydroxyacid dehydrogenase
family protein - Treponema denticola
Length = 292
Score = 97.1 bits (231), Expect = 5e-19
Identities = 61/212 (28%), Positives = 95/212 (44%)
Frame = +3
Query: 183 NVAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGVTPANSIXXXXXXXXXXX 362
+V F+GLG MG MA L G + + +K + G +
Sbjct: 7 DVGFIGLGVMGKSMAERLRAAGAKMHVFTRTKKSAEEILSKGAIWYDDPASLAPNCKIIF 66
Query: 363 SILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAPVS 542
+I+ + V + Y G+ G++ AK G++ D +T P + K+I+ A +K DAPVS
Sbjct: 67 TIVGYPQDVEETYFGEKGLLKTAKPGTIFADMTTSSPILAKKIYDEAKKKECFSVDAPVS 126
Query: 543 GGVMGAQNATLAFMAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMGITG 722
GG +GA+N TL+ MAGG + F+ P MG G G+GQ K+ N + +
Sbjct: 127 GGDIGAKNGTLSIMAGGDESAFKELEPFFACMGKTWALQGGAGAGQHTKMANQIAVAANL 186
Query: 723 MAXAECMXMGIKMGLXPKVLLDVLNNSSXRSW 818
E + GL P +L + + SW
Sbjct: 187 FGTVEAVCYAEAAGLDPHKMLSAIGGGAAGSW 218
>UniRef50_A0R1N4 Cluster: 6-phosphogluconate dehydrogenase,
NAD-binding; n=3; Mycobacterium|Rep: 6-phosphogluconate
dehydrogenase, NAD-binding - Mycobacterium smegmatis
(strain ATCC 700084 / mc(2)155)
Length = 272
Score = 96.7 bits (230), Expect = 7e-19
Identities = 61/210 (29%), Positives = 94/210 (44%)
Frame = +3
Query: 186 VAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGVTPANSIXXXXXXXXXXXS 365
V F+GLG+ G MA +V+ GF + +L A A +
Sbjct: 3 VGFIGLGSQGAPMARRIVEGGFETTLWARRPASLEPFADTAAKVAGTPAELAAASDLVCL 62
Query: 366 ILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAPVSG 545
+ + V +V G+ GV+A G ++ ST+ P+ +I EKG+ DAPVSG
Sbjct: 63 CVVGDDDVREVLDGETGVLAGLAPGGIIAIHSTVHPDTCTEIAEQVAEKGISLIDAPVSG 122
Query: 546 GVMGAQNATLAFMAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMGITGM 725
G A+ TL MAGG ++ ++ P+ G +GSGQVAK+ NN+L
Sbjct: 123 GEPAAKAGTLLVMAGGDEDIVDKVRPVFATYADPVVRLGGVGSGQVAKILNNLLFSANLG 182
Query: 726 AXAECMXMGIKMGLXPKVLLDVLNNSSXRS 815
A + +G +G+ L +V+ S S
Sbjct: 183 AAMSALELGEALGVPRSALCEVITRGSANS 212
>UniRef50_A0QUD5 Cluster: 3-hydroxyisobutyrate dehydrogenase family
protein; n=1; Mycobacterium smegmatis str. MC2 155|Rep:
3-hydroxyisobutyrate dehydrogenase family protein -
Mycobacterium smegmatis (strain ATCC 700084 / mc(2)155)
Length = 326
Score = 96.7 bits (230), Expect = 7e-19
Identities = 62/212 (29%), Positives = 102/212 (48%)
Frame = +3
Query: 180 KNVAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGVTPANSIXXXXXXXXXX 359
+ V FLGLGNMG MA LV G + Y+ + A G A S+
Sbjct: 11 QRVGFLGLGNMGRPMARRLVASGTPLTVYNRTAAKCAEFADLGCEVAESVARMGHCSVLL 70
Query: 360 XSILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAPV 539
+ T + V VYLG DG+VA+A+ G++L+D STI P++ ++ G+ F APV
Sbjct: 71 TMLGTDDDVA-QVYLGDDGLVANARAGAVLVDCSTISPDMSARVRARCDRAGVHFLAAPV 129
Query: 540 SGGVMGAQNATLAFMAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMGIT 719
+GG ++ LA G ++ FE + +L+V+ + G + ++ K+ +N+L+ T
Sbjct: 130 AGGPPVIESGGLAMAVSGDRQAFEHAADVLRVVAPNLIYVGPGDTSRLVKICHNLLVAAT 189
Query: 720 GMAXAECMXMGIKMGLXPKVLLDVLNNSSXRS 815
E + G + LL L +++ S
Sbjct: 190 LEVLGELCVLAESHGASRQALLSFLRSTAISS 221
>UniRef50_A0NRG5 Cluster: 6-phosphogluconate dehydrogenase,
NAD-binding protein; n=1; Stappia aggregata IAM
12614|Rep: 6-phosphogluconate dehydrogenase, NAD-binding
protein - Stappia aggregata IAM 12614
Length = 291
Score = 96.7 bits (230), Expect = 7e-19
Identities = 62/208 (29%), Positives = 95/208 (45%), Gaps = 1/208 (0%)
Frame = +3
Query: 186 VAFLGLGNMGGFMAANLVKKGFTVRGYDPSKD-ALNAAAKNGVTPANSIXXXXXXXXXXX 362
V F GLG MG MAANL G V ++ + + A A+ + PA +
Sbjct: 3 VGFAGLGRMGVRMAANLAAAGLEVSIWNRTAETARTFASAHNAFPAATPKDLAERSDIVI 62
Query: 363 SILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAPVS 542
++L + VY G DG+ + +L++ T+ + +++ A EKG F DAPVS
Sbjct: 63 TMLADDAAAETVYFGPDGLFEASSGAQVLVEMGTLSVPMAERLARAAQEKGRRFVDAPVS 122
Query: 543 GGVMGAQNATLAFMAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMGITG 722
G A++A L MAG D L V+G K G+ G+G KL NML+
Sbjct: 123 GATQAAKDAKLLIMAGATASDAPELAALFDVLGRKTIWLGKAGAGAAMKLGVNMLIHGLN 182
Query: 723 MAXAECMXMGIKMGLXPKVLLDVLNNSS 806
AE + + G+ + +V+ NS+
Sbjct: 183 QTLAEALSLTTAAGIPQEQAYEVVENSA 210
>UniRef50_Q4WV01 Cluster: Oxidoreductase, acting on the CH-OH group
of donors, NAD or NADP as acceptor; n=7;
Pezizomycotina|Rep: Oxidoreductase, acting on the CH-OH
group of donors, NAD or NADP as acceptor - Aspergillus
fumigatus (Sartorya fumigata)
Length = 435
Score = 96.7 bits (230), Expect = 7e-19
Identities = 63/217 (29%), Positives = 100/217 (46%), Gaps = 6/217 (2%)
Frame = +3
Query: 186 VAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGVTPANSIXXXXXXXXXXXS 365
+ F+GLG MG MA NLV++G+ V G+D ++ G PA+S+
Sbjct: 6 IGFVGLGAMGFGMATNLVREGYPVVGFDVFPASVQRFQSQGGIPASSLRESAEGKDFYIC 65
Query: 366 ILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKG---LGFTDAP 536
++ S V V G DGVV K + L ST+ + + + +G + F D P
Sbjct: 66 MVASAPQVQSVLFGDDGVVQFLPKNATLFLCSTVPASYAQSVAAELQSRGRADIRFIDCP 125
Query: 537 VSGGVMGAQNATLAFMAGGRKEDFERSLPLLKVMGAKQ---FHCGQIGSGQVAKLTNNML 707
VSGG A + TL+ MAG +E +L+VM + G +G+G K+ + +L
Sbjct: 126 VSGGAKRAADGTLSIMAGASEEALNSGREILQVMSDQNKLYLVPGGVGAGSNMKMVHQVL 185
Query: 708 MGITGMAXAECMXMGIKMGLXPKVLLDVLNNSSXRSW 818
GI + +E M ++GL K + + S +W
Sbjct: 186 AGIHILGASEAMGFAAQLGLDAKTTAEKIIGSEAWTW 222
>UniRef50_A0LDJ3 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=1;
Magnetococcus sp. MC-1|Rep: 3-hydroxyisobutyrate
dehydrogenase - Magnetococcus sp. (strain MC-1)
Length = 292
Score = 96.3 bits (229), Expect = 9e-19
Identities = 60/208 (28%), Positives = 95/208 (45%)
Frame = +3
Query: 180 KNVAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGVTPANSIXXXXXXXXXX 359
+ + F+GLG MG MA + G+ + Y+ L + A +
Sbjct: 2 QKIGFIGLGIMGSAMANSCHHAGYQLCVYNRGHARLKPFIDRSIPTAATPQALATQSDYM 61
Query: 360 XSILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAPV 539
+++ +L+V G GV + G ++I++ST+ +Q + + G F DAPV
Sbjct: 62 VIMVSDPAALLEVLQGPVGVCSADLTGKVVINASTVSVEASQQAATLVEQVGGAFLDAPV 121
Query: 540 SGGVMGAQNATLAFMAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMGIT 719
SG + AQ L F+AGG +R PLL MG+ CG +G G KL N+LM
Sbjct: 122 SGSKIPAQTGKLVFLAGGHHAVIQRCEPLLLSMGSAVIPCGAVGDGTRMKLAMNLLMSGM 181
Query: 720 GMAXAECMXMGIKMGLXPKVLLDVLNNS 803
A AE + + GL ++ +D + NS
Sbjct: 182 VQALAESLLLVRNSGLEDQLFMDAIKNS 209
>UniRef50_O33730 Cluster: Uncharacterized oxidoreductase Sfri_1503;
n=167; Bacteria|Rep: Uncharacterized oxidoreductase
Sfri_1503 - Shewanella frigidimarina (strain NCIMB 400)
Length = 291
Score = 96.3 bits (229), Expect = 9e-19
Identities = 60/212 (28%), Positives = 102/212 (48%), Gaps = 1/212 (0%)
Frame = +3
Query: 186 VAFLGLGNMGGFMAANLVKKGFTVRGYDPS-KDALNAAAKNGVTPANSIXXXXXXXXXXX 362
VAF+GLG MG MA +LVK+G V Y+ + A + G A++
Sbjct: 4 VAFIGLGVMGFPMAGHLVKQGHDVTVYNRTGAKATQWVEQYGGKKADTPKDAAQGQDIVF 63
Query: 363 SILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAPVS 542
+ + ++ + V LG+ G+V G++L+D +T +V ++I + F DAPVS
Sbjct: 64 TCVGNDDDLRQVVLGEHGIVHGMHAGAILVDHTTASADVAREIAAYIEPLNIAFLDAPVS 123
Query: 543 GGVMGAQNATLAFMAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMGITG 722
GG GA+N L M GG + F+ P++ G +G+GQ+ K+ N + +
Sbjct: 124 GGQAGAENGALTVMMGGDQAHFDTVKPVISAYSRCAELLGPVGAGQLTKMVNQICIAGVV 183
Query: 723 MAXAECMXMGIKMGLXPKVLLDVLNNSSXRSW 818
AE + GL +++V++ + +SW
Sbjct: 184 QGLAEGLHFAKSAGLDGLKVIEVISKGAAQSW 215
>UniRef50_Q8EW87 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=1;
Mycoplasma penetrans|Rep: 3-hydroxyisobutyrate
dehydrogenase - Mycoplasma penetrans
Length = 288
Score = 95.5 bits (227), Expect = 2e-18
Identities = 60/212 (28%), Positives = 99/212 (46%), Gaps = 1/212 (0%)
Frame = +3
Query: 186 VAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGVTPANSIXXXXXXXXXXXS 365
+ ++G G MG M L G + Y+ + + +N + SI +
Sbjct: 3 ITWIGTGIMGKAMLNRLASHGHIIHAYNRTYEKMNDLNHPNILKFRSIKDAVKDTNIIMT 62
Query: 366 ILTSNKVVLDVYLGKD-GVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAPVS 542
++ VLD+YL + G+ + + ID +T PN Q+ + KG+ DAPV+
Sbjct: 63 MVGYPSDVLDIYLNDEYGIFNYVSSEQICIDFTTSSPNFAVQLANNS--KGIKVLDAPVT 120
Query: 543 GGVMGAQNATLAFMAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMGITG 722
GG +GA N TL+ M GG E F++ +LK++G K + G G GQ AKL N +L+ +
Sbjct: 121 GGDIGALNGTLSIMVGGDFETFKKVESILKILGNKINYFGSAGKGQHAKLFNQILVAVNT 180
Query: 723 MAXAECMXMGIKMGLXPKVLLDVLNNSSXRSW 818
A AE + K + + V + + +W
Sbjct: 181 FATAEVLNYCKKNNVDIEAAYKVFDKTIGNNW 212
>UniRef50_Q89RT2 Cluster: Bll2680 protein; n=1; Bradyrhizobium
japonicum|Rep: Bll2680 protein - Bradyrhizobium
japonicum
Length = 300
Score = 95.5 bits (227), Expect = 2e-18
Identities = 57/216 (26%), Positives = 101/216 (46%)
Frame = +3
Query: 168 SNTDKNVAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGVTPANSIXXXXXX 347
++ +NVAF+G+G MG M+ + K G+ V +D S N A G++ A S
Sbjct: 2 TDASRNVAFIGIGKMGLPMSVLVAKAGYAVTAFDRSAARTNEARAQGISIAASPDDAVSG 61
Query: 348 XXXXXSILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFT 527
+ L + + LG GV+A G++LI++ST+ ++ A +G+ +
Sbjct: 62 KEAVITSLPDDTALRGALLGPAGVIAAMAPGAVLIETSTVSVEASTEVAASAQARGVLYL 121
Query: 528 DAPVSGGVMGAQNATLAFMAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNML 707
APVSG L G K+ F+ + PL + + G + AKL N++
Sbjct: 122 RAPVSGNASIVHTGALTCFVSGPKDAFDNAKPLFAAFTRARTYLGPAEEARYAKLAVNLM 181
Query: 708 MGITGMAXAECMXMGIKMGLXPKVLLDVLNNSSXRS 815
+ ++ AE + + K G+ + +L VL++S+ S
Sbjct: 182 IAVSAAMMAESLALARKGGIAWQDILKVLDDSAVAS 217
>UniRef50_Q9LM23 Cluster: Fructose-bisphosphate aldolase; n=2;
Arabidopsis thaliana|Rep: Fructose-bisphosphate aldolase
- Arabidopsis thaliana (Mouse-ear cress)
Length = 1486
Score = 95.5 bits (227), Expect = 2e-18
Identities = 71/223 (31%), Positives = 102/223 (45%), Gaps = 12/223 (5%)
Frame = +3
Query: 186 VAFLGLGNMGGFMAANLVKKGFTVRGYDPS---------KDALNAAAKNGVTPANSIXXX 338
+ F+GLG MG MAA+L+K F+V GYD S K L G ANS
Sbjct: 348 IGFIGLGAMGFGMAAHLLKSNFSVCGYDISLRLAVSSVYKPTLVRFENAGGLAANSPAEV 407
Query: 339 XXXXXXXXSILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKG- 515
++T+ DV G G V G+ ++ +ST+ P Q+ +G
Sbjct: 408 TKDVDVLVIMVTNEVQAEDVLYGHLGAVEAIPSGATVVLASTVSPAFVSQLERRLENEGK 467
Query: 516 -LGFTDAPVSGGVMGAQNATLAFMAGGRKEDFERSLPLLKVMGAKQFHC-GQIGSGQVAK 689
L DAPVSGGV A L MA G E + + +L + K + G G+G K
Sbjct: 468 DLKLVDAPVSGGVKRAAMGELTIMASGTDEALKSAGLVLSALSEKLYVIKGGCGAGSGVK 527
Query: 690 LTNNMLMGITGMAXAECMXMGIKMGLXPKVLLDVLNNSSXRSW 818
+ N +L G+ + AE M G ++GL + L +V++NS SW
Sbjct: 528 MVNQLLAGVHIASAAEAMAFGARLGLNTRKLFNVISNSGGTSW 570
Score = 59.3 bits (137), Expect = 1e-07
Identities = 31/98 (31%), Positives = 52/98 (53%), Gaps = 1/98 (1%)
Frame = +3
Query: 528 DAPVSGGVMGAQNATLAFMAGGRKEDFERSLPLLKVMGAKQFHC-GQIGSGQVAKLTNNM 704
DA V G+ + L +A GR + R+ P L M + G+IG+G K+ N +
Sbjct: 145 DAYVLKGMSELLDGKLMIIASGRSDSITRAQPYLTAMCQNLYTFEGEIGAGSKVKMVNEL 204
Query: 705 LMGITGMAXAECMXMGIKMGLXPKVLLDVLNNSSXRSW 818
L GI +A E + +G + G+ P +L D+++N++ SW
Sbjct: 205 LEGIHLVAAVEAISLGSQAGVHPWILYDIISNAAGNSW 242
>UniRef50_Q7WNK6 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=1;
Bordetella bronchiseptica|Rep: 3-hydroxyisobutyrate
dehydrogenase - Bordetella bronchiseptica (Alcaligenes
bronchisepticus)
Length = 306
Score = 95.1 bits (226), Expect = 2e-18
Identities = 60/211 (28%), Positives = 94/211 (44%), Gaps = 1/211 (0%)
Frame = +3
Query: 186 VAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGVTPANSIXXXXXXXXXXXS 365
+ F+GLG MGG + +L G V YD A+ AAA G PA S+
Sbjct: 9 IGFIGLGAMGGPICGHLAAAGHDVAAYDIQPAAVQAAAARGARPAASVREAADGAALLVV 68
Query: 366 ILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAPVSG 545
++ + V G+ G A G+ + +ST+ P + + E G G D PVSG
Sbjct: 69 MVHNAGQADAVLFGEGGAAAALPAGATVWLASTVAPAYARGLQARLREHGAGLVDGPVSG 128
Query: 546 GVMGAQNATLAFMAGGRKEDFERSLPLLKVMGAKQFHCG-QIGSGQVAKLTNNMLMGITG 722
G GAQ L +A G+ + + P ++ + G + G+ KL N +L
Sbjct: 129 GATGAQAGALTIIASGQAQALAAAEPAMRACSSIIHRVGEEAGAASTVKLVNQLLTASHI 188
Query: 723 MAXAECMXMGIKMGLXPKVLLDVLNNSSXRS 815
AE + +G + G+ P VL+ V++ S+ S
Sbjct: 189 ALTAEALALGARAGVDPDVLVKVISQSAGTS 219
>UniRef50_A6VYD9 Cluster: 2-hydroxy-3-oxopropionate reductase
precursor; n=5; Gammaproteobacteria|Rep:
2-hydroxy-3-oxopropionate reductase precursor -
Marinomonas sp. MWYL1
Length = 300
Score = 94.7 bits (225), Expect = 3e-18
Identities = 63/218 (28%), Positives = 98/218 (44%), Gaps = 1/218 (0%)
Frame = +3
Query: 168 SNTDKNVAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGVTPANSIXXXXXX 347
+N K+V +GLG+MG A + + G V G+D + AL G S
Sbjct: 2 TNKAKSVGVIGLGSMGMGAAKSCINAGLDVYGFDLNPKALEELNLAGAKAVASSALDFAD 61
Query: 348 XXXXXSILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFT 527
+L N ++ L G+ A K + ++ S+TI K I + L
Sbjct: 62 QLDAVLVLVVNAKQVNSVLFDSGLAAALKPQTAVMVSATISAEDAKAIHQKLSQYQLLML 121
Query: 528 DAPVSGGVMGAQNATLAFMAGGRKEDFERSLPLLKVMGAKQFHCG-QIGSGQVAKLTNNM 704
DAPVSGG A + MA G E FE+ P+L AK ++ G +IG G K+ + +
Sbjct: 122 DAPVSGGAAKAATGDMTVMASGSVEAFEKLQPVLDATAAKVYNIGEEIGLGATVKIIHQL 181
Query: 705 LMGITGMAXAECMXMGIKMGLXPKVLLDVLNNSSXRSW 818
L G+ A AE M + + + ++ DV+ N++ SW
Sbjct: 182 LAGVHIAAGAEAMALAARANIPLDLMYDVVTNAAGNSW 219
>UniRef50_Q46TQ0 Cluster: UDP-glucose/GDP-mannose
dehydrogenase:Prephenate dehydrogenase:NADP
oxidoreductase, coenzyme
F420-dependent:6-phosphogluconate dehydrogenase,
NAD-binding; n=1; Ralstonia eutropha JMP134|Rep:
UDP-glucose/GDP-mannose dehydrogenase:Prephenate
dehydrogenase:NADP oxidoreductase, coenzyme
F420-dependent:6-phosphogluconate dehydrogenase,
NAD-binding - Ralstonia eutropha (strain JMP134)
(Alcaligenes eutrophus)
Length = 294
Score = 94.3 bits (224), Expect = 4e-18
Identities = 60/210 (28%), Positives = 98/210 (46%)
Frame = +3
Query: 186 VAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGVTPANSIXXXXXXXXXXXS 365
+ F+G G MG MA ++ G V YD + + +AA G+ A S+ S
Sbjct: 3 IGFIGTGKMGLPMARHIAAAGHDVVAYDIAPEQASAARHAGLAVAPSLADAVSAAEVIFS 62
Query: 366 ILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAPVSG 545
+ N G+ + A+ G+L ID+ST+ P + P+ + + + VSG
Sbjct: 63 SMP-NDGAFSAVAGQ--IAKAARPGALYIDTSTVSPAASAAVAPLLAARDIAYLRVTVSG 119
Query: 546 GVMGAQNATLAFMAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMGITGM 725
A+ A L + G + +ER PLL +G QF+ G ++ KL N+L+ +TG
Sbjct: 120 NNHMAEAAKLTALVSGPADAYERIKPLLAALGPAQFYLGDAEQARLMKLVVNLLIALTGG 179
Query: 726 AXAECMXMGIKMGLXPKVLLDVLNNSSXRS 815
AE + +G K GL + + DV+ S+ S
Sbjct: 180 MLAEALTLGSKGGLEWQAMWDVITASAVAS 209
>UniRef50_Q2BFK1 Cluster: Oxidoreductase; n=1; Bacillus sp. NRRL
B-14911|Rep: Oxidoreductase - Bacillus sp. NRRL B-14911
Length = 270
Score = 94.3 bits (224), Expect = 4e-18
Identities = 61/200 (30%), Positives = 94/200 (47%), Gaps = 1/200 (0%)
Frame = +3
Query: 222 MAANLVKKGFTVR-GYDPSKDALNAAAKNGVTPANSIXXXXXXXXXXXSILTSNKVVLDV 398
MA NL K G+ + ++ + G +S SIL ++K + V
Sbjct: 1 MAKNLQKNGYDLHITAHNNRKPVEELTSMGAVEHSSAADVVSNSEVIISILPADKEMESV 60
Query: 399 YLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAPVSGGVMGAQNATLA 578
L ++ V+ G LI+ ++ P + K++ +KG+ D PVSGG GA+N TL
Sbjct: 61 LLSEE-VLNVLNPGQFLIEMTSGSPEMMKKVHAAYQQKGIPVLDGPVSGGTAGAENGTLT 119
Query: 579 FMAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMGITGMAXAECMXMGIK 758
MAGG + ER P+L+ M + G +G G+ K N ML GI A AE + + K
Sbjct: 120 VMAGGDADVLERLRPVLESMATNIYLVGSVGDGKAIKAINQMLAGIHMAAAAEAVALAEK 179
Query: 759 MGLXPKVLLDVLNNSSXRSW 818
+ + L V+ +SS SW
Sbjct: 180 LEIDMDKLKAVVGSSSGNSW 199
>UniRef50_Q1B326 Cluster: 6-phosphogluconate dehydrogenase,
NAD-binding protein precursor; n=7; Bacteria|Rep:
6-phosphogluconate dehydrogenase, NAD-binding protein
precursor - Mycobacterium sp. (strain MCS)
Length = 299
Score = 94.3 bits (224), Expect = 4e-18
Identities = 60/211 (28%), Positives = 103/211 (48%), Gaps = 1/211 (0%)
Frame = +3
Query: 174 TDKNVAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGVTPANSIXXXXXXXX 353
++ ++ F+GLGNMG MAANL+ G V Y+ S D ++A + G PA ++
Sbjct: 2 SNMHIGFIGLGNMGSAMAANLLAAGHDVTAYNRSPDKVDALSAEGARPARTV-AEACQGD 60
Query: 354 XXXSILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDA 533
++L ++ V V G DG+VA + ++ + SSTI + +++ E G F A
Sbjct: 61 VVVTMLANDDAVEAVSFGDDGIVASLRPDAIHVSSSTISLALAERLTAAHAEGGSRFVSA 120
Query: 534 PVSGGVMGAQNATLAFMAGGRKEDFERSLPLLKVMGAKQFHCG-QIGSGQVAKLTNNMLM 710
PV G A A L +A G + E P+ + +G + F G + + + K++ N L+
Sbjct: 121 PVFGRPEAAAAAKLFVVAAGAPDTVEALAPVFEAIGQRTFVVGTEPKAANLVKVSGNFLI 180
Query: 711 GITGMAXAECMXMGIKMGLXPKVLLDVLNNS 803
+ E M + K G+ LD+L ++
Sbjct: 181 ASVIESLGEAMALVAKGGVDVDQYLDLLTST 211
>UniRef50_Q7NR40 Cluster: Probable 3-hydroxyisobutyrate
dehydrogenase; n=1; Chromobacterium violaceum|Rep:
Probable 3-hydroxyisobutyrate dehydrogenase -
Chromobacterium violaceum
Length = 296
Score = 93.9 bits (223), Expect = 5e-18
Identities = 63/219 (28%), Positives = 99/219 (45%), Gaps = 4/219 (1%)
Frame = +3
Query: 171 NTDKNVAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDAL----NAAAKNGVTPANSIXXX 338
N K +A +G G MG + L+ G+ VR Y+ S + +A A TPA ++
Sbjct: 5 NAGKRLALIGCGAMGTALGLRLLGLGWEVRVYNRSPERTAPLRDAGASAHATPAEAVAGA 64
Query: 339 XXXXXXXXSILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGL 518
++LT + + + G +G+ + G L+D T P + A G
Sbjct: 65 DWVA----TVLTDSAALRALLFGDNGIASAPAAGRRLVDLGTHQPTQLAALGAEAAAAGW 120
Query: 519 GFTDAPVSGGVMGAQNATLAFMAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTN 698
+AP++G V A + TL F+ GG + D E + PLL +G H G +G+G AKL
Sbjct: 121 PLVEAPMTGSVHDASHGTLHFLVGGAEADVEWASPLLWALGRGVHHLGGLGAGNTAKLAL 180
Query: 699 NMLMGITGMAXAECMXMGIKMGLXPKVLLDVLNNSSXRS 815
N+L+G+ E + + GL LD L+ S S
Sbjct: 181 NLLVGVMAGGLGEAIALLRAHGLAVDSFLDALDGSGLAS 219
>UniRef50_Q6UCZ9 Cluster: Predicted oxidoreductase; n=2;
environmental samples|Rep: Predicted oxidoreductase -
uncultured marine proteobacterium ANT32C12
Length = 309
Score = 93.9 bits (223), Expect = 5e-18
Identities = 57/212 (26%), Positives = 104/212 (49%), Gaps = 1/212 (0%)
Frame = +3
Query: 186 VAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGVTPANSIXXXXXXXXXXXS 365
+ F+GLG MG MA +L K+ + ++ S++ + A +
Sbjct: 23 IGFIGLGVMGYPMAGHLSKEFSNICIFNRSQEKVTKWLNQYSGTAFDTPEELSSQCNVIA 82
Query: 366 ILTS-NKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAPVS 542
+ ++ V ++ GK G++ G+++ID +T + K++ +AL+K + F DAP+S
Sbjct: 83 LCVGRDEDVREMMSGKKGILNSVNPGTIIIDHTTTSATLSKEMNELALQKDVIFLDAPIS 142
Query: 543 GGVMGAQNATLAFMAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMGITG 722
GG GA++ L+ M GG K +E P+L + G GSGQ+ K+ N + +
Sbjct: 143 GGQAGAESGQLSVMVGGDKASYESVKPILDNYSKFTKYMGPSGSGQLTKMVNQICIAGLV 202
Query: 723 MAXAECMXMGIKMGLXPKVLLDVLNNSSXRSW 818
A AE + K+GL +++V+ + +SW
Sbjct: 203 QALAEGVNFSEKVGLNTSDVMEVITKGAAQSW 234
>UniRef50_Q3W9W7 Cluster: 6-phosphogluconate dehydrogenase, NAD
binding domain; n=2; Frankia sp. EAN1pec|Rep:
6-phosphogluconate dehydrogenase, NAD binding domain -
Frankia sp. EAN1pec
Length = 286
Score = 93.9 bits (223), Expect = 5e-18
Identities = 64/218 (29%), Positives = 106/218 (48%), Gaps = 1/218 (0%)
Frame = +3
Query: 174 TDKNVAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGVTPANSIXXXXXXXX 353
T +V F+GLGNMGG +AAN+ + G + +D + A G T + +
Sbjct: 2 TAPSVGFVGLGNMGGALAANVAQFGLDLVVHDAAGPE---RAPEGTTHLDDLAAVARHAE 58
Query: 354 XXXSILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDA 533
+L+ V+ + + ++ + ++D+STI + ++I + G+G+ DA
Sbjct: 59 VV--VLSLPDGVISEKVARGLAETADRRVTHVVDTSTIGVSAAQRITDLLAASGIGYVDA 116
Query: 534 PVSGGVMGAQNATLAFMAGGRKEDFERSLPLLKVMGAKQFHCG-QIGSGQVAKLTNNMLM 710
PVSGGV GA+ TL M G + R P+L + ++ G + G Q KL NN L
Sbjct: 117 PVSGGVTGARARTLTVMYAGTDDACARVEPVLAALSDRRRRVGDRPGLAQALKLANNFLA 176
Query: 711 GITGMAXAECMXMGIKMGLXPKVLLDVLNNSSXRSWST 824
+ A +E + G GL +LDVLN +S ++ +T
Sbjct: 177 AVALAATSEAVAFGTSAGLDMGTMLDVLNTASGQNNAT 214
>UniRef50_A4SWE8 Cluster: 2-hydroxy-3-oxopropionate reductase
precursor; n=7; Proteobacteria|Rep:
2-hydroxy-3-oxopropionate reductase precursor -
Polynucleobacter sp. QLW-P1DMWA-1
Length = 299
Score = 93.1 bits (221), Expect = 9e-18
Identities = 63/206 (30%), Positives = 96/206 (46%), Gaps = 3/206 (1%)
Frame = +3
Query: 186 VAFLGLGNMGGFMAANLVKKGFTVRGYDPSK---DALNAAAKNGVTPANSIXXXXXXXXX 356
+ F+GLG MG MA++L+ G + SK + N+AA TPA
Sbjct: 6 LGFIGLGIMGAPMASHLMAAGHALFINTRSKVPEELANSAAVVCATPAE----VAKMADI 61
Query: 357 XXSILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAP 536
+++ V V G+ GV KG +++D S+I P K G + DAP
Sbjct: 62 IFTMVPDTPDVEKVLFGEHGVAHGLSKGKIVVDMSSISPIATKDFAKKINALGCEYLDAP 121
Query: 537 VSGGVMGAQNATLAFMAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMGI 716
VSGG +GA+ TL M GG++ F+ P+ +MG G G+GQV K+ N +++ +
Sbjct: 122 VSGGQVGAKGGTLTIMVGGKESVFQTVKPMFDLMGKNITLVGDNGAGQVTKVANQIIVAL 181
Query: 717 TGMAXAECMXMGIKMGLXPKVLLDVL 794
A AE + K G P + + L
Sbjct: 182 NIEAVAEALLFASKAGADPARVREAL 207
>UniRef50_Q9JYH6 Cluster: 3-hydroxyacid dehydrogenase; n=5;
Proteobacteria|Rep: 3-hydroxyacid dehydrogenase -
Neisseria meningitidis serogroup B
Length = 289
Score = 92.7 bits (220), Expect = 1e-17
Identities = 61/218 (27%), Positives = 97/218 (44%), Gaps = 1/218 (0%)
Frame = +3
Query: 165 SSNTDKNVAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGVTPANSIXXXXX 344
S+N + ++GLG MG M L+ G V Y+ S D + G +
Sbjct: 2 SANEYAQIGWIGLGQMGLPMVTRLLDGGIEVGVYNRSPDKTAPISAKGAKVYGNTAELVR 61
Query: 345 XXXXXXSILTSNKVVLDVYLG-KDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLG 521
+++ V D+ G +DG+ G ++++ STI P + + G
Sbjct: 62 DYPVIFLMVSDYAAVCDILNGVRDGLA-----GKIIVNMSTISPTENLAVKALVEAAGGQ 116
Query: 522 FTDAPVSGGVMGAQNATLAFMAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNN 701
F +APVSG V A N TL + GG + + ++G K FH G +G G AKL N
Sbjct: 117 FAEAPVSGSVGPATNGTLLILFGGSEAVLNPLQKIFSLVGKKTFHFGDVGKGSGAKLVLN 176
Query: 702 MLMGITGMAXAECMXMGIKMGLXPKVLLDVLNNSSXRS 815
L+GI G A +E M M + G+ +++ + S+ S
Sbjct: 177 SLLGIFGEAYSEAMLMARQFGIDTDTIVEAIGGSAMDS 214
>UniRef50_A1CAY2 Cluster: Oxidoreductase, acting on the CH-OH group
of donors, NAD or NADP as acceptor; n=2;
Aspergillus|Rep: Oxidoreductase, acting on the CH-OH
group of donors, NAD or NADP as acceptor - Aspergillus
clavatus
Length = 436
Score = 92.7 bits (220), Expect = 1e-17
Identities = 63/217 (29%), Positives = 100/217 (46%), Gaps = 6/217 (2%)
Frame = +3
Query: 186 VAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGVTPANSIXXXXXXXXXXXS 365
+ F+GLG MG MA NLV++G+ V GYD ++ G PA+S+
Sbjct: 6 IGFVGLGAMGFGMATNLVREGYPVVGYDVFPASVQRFQTAGGIPASSLRESAEGKDFYVC 65
Query: 366 ILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKG---LGFTDAP 536
++ S V V G DG+V + + L ST+ + + + G + F D P
Sbjct: 66 MVASAPQVQSVLFGDDGIVQYLPPNATLFLCSTVPASYAQSVAAELQSLGRADIRFIDCP 125
Query: 537 VSGGVMGAQNATLAFMAGGRKEDFERSLPLLKVMG-AKQFHC--GQIGSGQVAKLTNNML 707
VSGG A + TL+ MAG +E +L+VM K+ + G IG+G K+ + +L
Sbjct: 126 VSGGAKRAADGTLSIMAGAPEEALNSGREILQVMSDQKKLYLVPGGIGAGSNMKMVHQVL 185
Query: 708 MGITGMAXAECMXMGIKMGLXPKVLLDVLNNSSXRSW 818
GI + +E M ++GL K + + +W
Sbjct: 186 AGIHILGASEAMGFAAQLGLDAKTTAAKIIGTEAWTW 222
>UniRef50_Q89M84 Cluster: Blr4309 protein; n=6;
Bradyrhizobiaceae|Rep: Blr4309 protein - Bradyrhizobium
japonicum
Length = 293
Score = 91.9 bits (218), Expect = 2e-17
Identities = 60/201 (29%), Positives = 95/201 (47%)
Frame = +3
Query: 186 VAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGVTPANSIXXXXXXXXXXXS 365
VAF+GLG MG MA + GFTV ++ SK G A S +
Sbjct: 4 VAFIGLGRMGHGMAGRYLDAGFTVTLWNRSKTKAEDLIARGAHWATSPEDAAIDADAVVT 63
Query: 366 ILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAPVSG 545
++ ++ V+LG G AK G++ I+ ST+ + +++ +GL + D PV+G
Sbjct: 64 MVADDEASRAVWLGPKGAAKTAKAGTIAIECSTVSYDHAREMGRELNARGLIYIDCPVTG 123
Query: 546 GVMGAQNATLAFMAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMGITGM 725
A L + G D ER+ P L+ +G+ H G +GSG V KL NN++ I
Sbjct: 124 LPDAAAAGKLTLLVGADAADLERARPYLEPIGSTIRHFGAVGSGTVYKLINNLMGAIQIA 183
Query: 726 AXAECMXMGIKMGLXPKVLLD 788
AE + + + GL ++L+
Sbjct: 184 GLAEGLAIAEQAGLDMTLVLE 204
>UniRef50_O66454 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=3;
cellular organisms|Rep: 3-hydroxyisobutyrate
dehydrogenase - Aquifex aeolicus
Length = 288
Score = 91.5 bits (217), Expect = 3e-17
Identities = 58/212 (27%), Positives = 104/212 (49%), Gaps = 1/212 (0%)
Frame = +3
Query: 186 VAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKN-GVTPANSIXXXXXXXXXXX 362
V F+GLG++G +A L+++G + ++ + + AK G +S
Sbjct: 3 VGFIGLGHLGRAIAKRLIEQGVELIVWNRTLSKAHEFAKETGAEVTSSPADLINKVDRVF 62
Query: 363 SILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAPVS 542
I+ ++ +V G+ G+V KG +ID +T ++ + + G + DAPV
Sbjct: 63 VIVFDSQASEEVIFGEKGLVKGDIKGKTVIDMTTNHYLYAQKAYEELKKLGAFYLDAPVL 122
Query: 543 GGVMGAQNATLAFMAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMGITG 722
G V+ A L + GG KE FE + PL + ++ G+ G G KL NN+++G
Sbjct: 123 GSVIPALKGELTIVVGGDKEKFEENKPLFEKFCRAIYYLGEAGMGSKMKLVNNIVLGGIM 182
Query: 723 MAXAECMXMGIKMGLXPKVLLDVLNNSSXRSW 818
AE + +G K G+ + L++VLN+ + +S+
Sbjct: 183 EVLAEAIAIGEKAGIDKETLINVLNDGAGKSY 214
>UniRef50_P77161 Cluster: 2-hydroxy-3-oxopropionate reductase; n=99;
Proteobacteria|Rep: 2-hydroxy-3-oxopropionate reductase
- Escherichia coli (strain K12)
Length = 292
Score = 91.5 bits (217), Expect = 3e-17
Identities = 61/198 (30%), Positives = 91/198 (45%), Gaps = 2/198 (1%)
Frame = +3
Query: 186 VAFLGLGNMGGFMAANLVKKGFT--VRGYDPSKDALNAAAKNGVTPANSIXXXXXXXXXX 359
+ F+GLG MG MA NL + G V P D L + V A +
Sbjct: 3 LGFIGLGIMGTPMAINLARAGHQLHVTTIGPVADELLSLGAVSVETARQVTEASDIIFI- 61
Query: 360 XSILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAPV 539
++ V +V G++G + KG ++D S+I P K+ E G + DAPV
Sbjct: 62 --MVPDTPQVEEVLFGENGCTKASLKGKTIVDMSSISPIETKRFARQVNELGGDYLDAPV 119
Query: 540 SGGVMGAQNATLAFMAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMGIT 719
SGG +GA+ TL+ M GG + FER PL +++G G G GQ K+ N +++ +
Sbjct: 120 SGGEIGAREGTLSIMVGGDEAVFERVKPLFELLGKNITLVGGNGDGQTCKVANQIIVALN 179
Query: 720 GMAXAECMXMGIKMGLXP 773
A +E + K G P
Sbjct: 180 IEAVSEALLFASKAGADP 197
>UniRef50_Q20XN2 Cluster: 6-phosphogluconate dehydrogenase,
NAD-binding; n=1; Rhodopseudomonas palustris BisB18|Rep:
6-phosphogluconate dehydrogenase, NAD-binding -
Rhodopseudomonas palustris (strain BisB18)
Length = 365
Score = 91.1 bits (216), Expect = 4e-17
Identities = 62/207 (29%), Positives = 98/207 (47%), Gaps = 1/207 (0%)
Frame = +3
Query: 186 VAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGVTPANSIXXXXXXXXXXXS 365
V +GLG MG A NL+ G + +D + ++A A+ GV A + S
Sbjct: 23 VGVVGLGRMGRAFAENLLADGHPIVVWDAFQTQIDAMARPGVVAATKLADLAECDVVFSS 82
Query: 366 ILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAPVSG 545
L ++ V V G G+V K G++ I STI P + +++ E G G+ APV G
Sbjct: 83 -LPDDEAVTAVAAGAGGLVKIMKAGAVHISMSTISPTMSRRLAAWHGECGQGYVAAPVLG 141
Query: 546 GVMGAQNATLAFMAGGRKEDFERSLPLLKVMGAKQFHCGQ-IGSGQVAKLTNNMLMGITG 722
A+ TL +A G +++ PLL +G K F G+ + + KL N+L +T
Sbjct: 142 NPDLARARTLFILAAGPDAAMQKARPLLDRLGQKLFVIGEDAAAANLVKLAGNVLTALTL 201
Query: 723 MAXAECMXMGIKMGLXPKVLLDVLNNS 803
+ E + + K G+ P+V D+ NS
Sbjct: 202 QSMGEVLALLRKSGIDPRVGFDIFTNS 228
>UniRef50_Q0KC92 Cluster: 3-Hydroxyisobutyrate dehydrogenase; n=1;
Ralstonia eutropha H16|Rep: 3-Hydroxyisobutyrate
dehydrogenase - Ralstonia eutropha (strain ATCC 17699 /
H16 / DSM 428 / Stanier 337)(Cupriavidus necator (strain
ATCC 17699 / H16 / DSM 428 / Stanier337))
Length = 305
Score = 91.1 bits (216), Expect = 4e-17
Identities = 54/206 (26%), Positives = 95/206 (46%)
Frame = +3
Query: 186 VAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGVTPANSIXXXXXXXXXXXS 365
+ ++G+G MG M NL+K G+ + +D A A G A + S
Sbjct: 15 LGWIGVGAMGRPMCLNLLKAGYRLTVFDRVPAQCEAVAAAGAAVAPAAQALVADSDVVFS 74
Query: 366 ILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAPVSG 545
+ + + D++L GV A + +D ST+ P+ ++ +G F APVSG
Sbjct: 75 TIFDDGGLRDLFLASGGVAGAATADKVFVDMSTVSPDASAEVAAALARRGAAFLRAPVSG 134
Query: 546 GVMGAQNATLAFMAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMGITGM 725
V A +A L+ G + F+ P+L + A+Q + G +V KL NM++ ++
Sbjct: 135 TVSLAASAQLSCFVSGPRPAFDAVQPVLACLTARQSYVGGADEARVIKLMINMMVFMSTA 194
Query: 726 AXAECMXMGIKMGLXPKVLLDVLNNS 803
E + G + GL +++D +N+S
Sbjct: 195 VIGEGLAFGARAGLNRALMVDAINDS 220
>UniRef50_Q019Z7 Cluster: Oxidoreductase-like; n=1; Ostreococcus
tauri|Rep: Oxidoreductase-like - Ostreococcus tauri
Length = 325
Score = 91.1 bits (216), Expect = 4e-17
Identities = 62/211 (29%), Positives = 97/211 (45%), Gaps = 1/211 (0%)
Frame = +3
Query: 168 SNTDKNVAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGVTPANSIXXXXXX 347
++T +AFLG G MG MA NL+ G V ++ ++ A + G T A +
Sbjct: 39 TSTPMKLAFLGCGIMGVPMAKNLIAAGHDVTVWNRTESATKPVVEAGATLAKTASEAARA 98
Query: 348 XXXXXSILTSNKVVLDV-YLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGF 524
++++ + L V + K+G+ G +D ST+D + I + G F
Sbjct: 99 ADVVFVMVSTPEAALAVAHAAKEGL----SSGKGYVDVSTVDAGTSRAIAEVVRSTGAEF 154
Query: 525 TDAPVSGGVMGAQNATLAFMAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNM 704
+APVSG A++ L F+ G + + R L VMG F G +G G KL NM
Sbjct: 155 LEAPVSGSKKPAEDGALIFLCAGDEGLYTRCTDPLDVMGKAHFFLGDVGQGAKMKLVVNM 214
Query: 705 LMGITGMAXAECMXMGIKMGLXPKVLLDVLN 797
+MG A AE + + K L + LL V++
Sbjct: 215 IMGSMMGAFAEGLTLADKSDLSQETLLQVIS 245
>UniRef50_Q9LNP0 Cluster: F1L3.35; n=8; Magnoliophyta|Rep: F1L3.35 -
Arabidopsis thaliana (Mouse-ear cress)
Length = 387
Score = 90.6 bits (215), Expect = 5e-17
Identities = 47/139 (33%), Positives = 76/139 (54%)
Frame = +3
Query: 390 LDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAPVSGGVMGAQNA 569
+DV GK+G + G +D ST+D I + G F +APVSG A++
Sbjct: 166 IDVACGKNGAIFGISSGKGYVDVSTVDVASSILISKQIKDTGALFLEAPVSGSKKPAEDG 225
Query: 570 TLAFMAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMGITGMAXAECMXM 749
L F+ G K +E++ P L +MG +F+ G++G+G KL NM+MG + AE + +
Sbjct: 226 QLIFLTAGDKPLYEKAAPFLDIMGKSKFYLGEVGNGAAMKLVVNMIMGSMMASFAEGILL 285
Query: 750 GIKMGLXPKVLLDVLNNSS 806
K+GL P VL++V++ +
Sbjct: 286 SQKVGLDPNVLVEVVSQGA 304
>UniRef50_Q98I20 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=2;
Alphaproteobacteria|Rep: 3-hydroxyisobutyrate
dehydrogenase - Rhizobium loti (Mesorhizobium loti)
Length = 305
Score = 90.2 bits (214), Expect = 6e-17
Identities = 58/196 (29%), Positives = 94/196 (47%)
Frame = +3
Query: 180 KNVAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGVTPANSIXXXXXXXXXX 359
++ AF+GLG++GG +A +L++ GF + +D A+ G T ANS
Sbjct: 3 ESYAFIGLGHLGGNLAPSLIRNGFAITVFDRDPAAVERLVTLGATAANSPAEAAARAGNA 62
Query: 360 XSILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAPV 539
+ L S K+ V G G++ KG I+ ST + ++ +A +G+ + PV
Sbjct: 63 ITCLPSPKISEAVLAGPGGLLEGLPKGGTWIEMSTNGRDEIMRLAALASAEGVETLECPV 122
Query: 540 SGGVMGAQNATLAFMAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMGIT 719
+GGV A + + GG +ER ++ M A+ F G IGS V K+ NML I
Sbjct: 123 TGGVHLAAVGKITALVGGDAALYERHRAAIEAMCARSFLMGPIGSAAVIKVITNMLAFIH 182
Query: 720 GMAXAECMXMGIKMGL 767
+A E + + + GL
Sbjct: 183 LVAAGEALMLAKQGGL 198
>UniRef50_Q7VYY0 Cluster: Putative oxidoreductase; n=4;
Bordetella|Rep: Putative oxidoreductase - Bordetella
pertussis
Length = 305
Score = 90.2 bits (214), Expect = 6e-17
Identities = 66/220 (30%), Positives = 102/220 (46%), Gaps = 8/220 (3%)
Frame = +3
Query: 180 KNVAFLGLGNMGGFMAANLV-KKGFTVRGYDPSKDALNAAAKNGV----TPANSIXXXXX 344
+ + F+GLG MG M NL + + + YD S A + A +
Sbjct: 3 QTLGFVGLGMMGLPMLENLAGDERWQILAYDRSPAPFERLAGHPAWGKRLRAAAGLQELA 62
Query: 345 XXXXXXSILTSNKVVLDVYLGKDG---VVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKG 515
++L ++ + V LG DG ++ + G+ ++D + +P +++ +G
Sbjct: 63 ACDTVITMLPNSAITNAVVLGGDGQPGLIDLLESGAAIVDMGSSNPADTRRLSEQLAARG 122
Query: 516 LGFTDAPVSGGVMGAQNATLAFMAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLT 695
L DAPVSG V A TLA MAG + D R P+L+ MGA H G +GS K
Sbjct: 123 LTLIDAPVSGAVAKASTGTLAIMAGAAEADLRRVRPILERMGAAIIHTGAVGSAHAMKAL 182
Query: 696 NNMLMGITGMAXAECMXMGIKMGLXPKVLLDVLNNSSXRS 815
NN + +A +E M + +M L +V DVLN SS R+
Sbjct: 183 NNYVYAAGLLAVSEAMVIARRMELDLEVFTDVLNASSGRN 222
>UniRef50_Q5LQR0 Cluster: 6-phosphogluconate dehydrogenase domain
protein; n=14; Proteobacteria|Rep: 6-phosphogluconate
dehydrogenase domain protein - Silicibacter pomeroyi
Length = 302
Score = 90.2 bits (214), Expect = 6e-17
Identities = 67/213 (31%), Positives = 98/213 (46%), Gaps = 4/213 (1%)
Frame = +3
Query: 168 SNTDK-NVAFLGLGNMGGFMAANLVKKGF--TVRGYDPSKDALNAAAKNGVTPANSIXXX 338
+N DK ++ F+GLG MG M L K G TV G + + + AA G T A
Sbjct: 4 NNMDKAHIGFIGLGLMGAAMVECLQKAGHAVTVLG-NRDRTGVEAALARGATEAAHARAV 62
Query: 339 XXXXXXXXSIL-TSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKG 515
+ TS +V +Y G DGV+A ++G ++ID T P ++I KG
Sbjct: 63 AEASDIVMLCMGTSAQVESRIY-GDDGVLAGTREGQVVIDFGTSLPASTRRIGGDLAGKG 121
Query: 516 LGFTDAPVSGGVMGAQNATLAFMAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLT 695
+ DAP+ A++ L M G K F+R P+L +G FH G +G+G KL
Sbjct: 122 ATYLDAPLGRTPAHARDGLLNIMCSGDKATFDRVKPVLHTLGENVFHLGALGNGHTIKLI 181
Query: 696 NNMLMGITGMAXAECMXMGIKMGLXPKVLLDVL 794
NN T A AE + G+ + L +V+
Sbjct: 182 NNCYSMTTACAMAEAFAIADATGIERQALYNVM 214
>UniRef50_Q5FQ06 Cluster: Putative oxidoreductase; n=1;
Gluconobacter oxydans|Rep: Putative oxidoreductase -
Gluconobacter oxydans (Gluconobacter suboxydans)
Length = 290
Score = 90.2 bits (214), Expect = 6e-17
Identities = 60/203 (29%), Positives = 90/203 (44%)
Frame = +3
Query: 186 VAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGVTPANSIXXXXXXXXXXXS 365
+ F+G G M M ANL K G+ V Y PS K+ S
Sbjct: 6 IGFIGYGAMAQRMGANLRKAGYPVVAYAPS------GGKDETEMLPSPRAIAEAAEIIIF 59
Query: 366 ILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAPVSG 545
+ ++ + G++G +A G L++D+ST+ P+ +A+E G DAP+SG
Sbjct: 60 CVPNDAAENESLHGENGALAALTPGKLVLDTSTVSPDQADAFASLAVEHGFSLLDAPMSG 119
Query: 546 GVMGAQNATLAFMAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMGITGM 725
A+ L + GG + +R+ P+L V+G H G GS KL N +MG T
Sbjct: 120 STPEAETGDLVMLVGGDEAVVKRAQPVLDVIGKLTIHAGPAGSAARLKLVVNGVMGATLN 179
Query: 726 AXAECMXMGIKMGLXPKVLLDVL 794
AE + G+ GL V+ D L
Sbjct: 180 VIAEGVSYGLAAGLDRDVVFDTL 202
>UniRef50_Q3W3N3 Cluster: Putative uncharacterized protein; n=1;
Frankia sp. EAN1pec|Rep: Putative uncharacterized
protein - Frankia sp. EAN1pec
Length = 315
Score = 90.2 bits (214), Expect = 6e-17
Identities = 62/238 (26%), Positives = 99/238 (41%)
Frame = +3
Query: 147 AARRAYSSNTDKNVAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGVTPANS 326
AA + SS ++ F+GLG+ G + G + YD D G++ A +
Sbjct: 3 AAPQGDSSLANETYGFVGLGHQGSQIVRRCASAGRHLVVYDTQTDRAEQFRPAGMSVAGT 62
Query: 327 IXXXXXXXXXXXSILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIAL 506
+ + S++ V V G G++ + GSL++ ST P + A
Sbjct: 63 LAELGRRVTVASVCVYSDEDVRTVVAGPGGLLETMRSGSLVVIHSTCSPRTCVDLAARAR 122
Query: 507 EKGLGFTDAPVSGGVMGAQNATLAFMAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVA 686
+G+ DAPVS G L +AGG + D +R P+ ++ G + G +GS Q+
Sbjct: 123 GRGITVLDAPVSNGAPDESGRQLVVLAGGDRRDVDRCAPVFELFGRTVVYTGDVGSAQLT 182
Query: 687 KLTNNMLMGITGMAXAECMXMGIKMGLXPKVLLDVLNNSSXRSWSTXXVLSXPRTGAH 860
KL NN L + A E + +GL P + L S + S + P G H
Sbjct: 183 KLVNNALFIVHRSAAIEALRAAGTLGLDPDGVRVALQECSANARS-LPIPGGPPIGGH 239
>UniRef50_Q2CHC8 Cluster: Oxidoreductase; n=1; Oceanicola granulosus
HTCC2516|Rep: Oxidoreductase - Oceanicola granulosus
HTCC2516
Length = 288
Score = 89.8 bits (213), Expect = 8e-17
Identities = 57/203 (28%), Positives = 91/203 (44%)
Frame = +3
Query: 186 VAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGVTPANSIXXXXXXXXXXXS 365
V +GLG MG M L ++GF R ++ + + G +S
Sbjct: 3 VGVIGLGIMGAPMVRRLRERGFETRVWNLEPERFAQVSDAGALWCDSPAGVRAASDIVVL 62
Query: 366 ILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAPVSG 545
+ + V DV G G+ A A +++D ST+ P + I A + DAPVSG
Sbjct: 63 CVLDGRAVEDVCFGAQGL-AGAGGAEIVVDCSTVPPEATRDI---AGRMDAAWIDAPVSG 118
Query: 546 GVMGAQNATLAFMAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMGITGM 725
G A+ L + GG++ D ER+ ++ + A H G +G+GQ AK N ++G+ +
Sbjct: 119 GPQLAETGELTMLLGGQERDIERARAVIDALAANATHLGPLGAGQAAKTLNQAIVGVNYV 178
Query: 726 AXAECMXMGIKMGLXPKVLLDVL 794
AE + + K G+ P L L
Sbjct: 179 LMAELLALARKSGIDPARLPQAL 201
>UniRef50_A0GPK7 Cluster: 6-phosphogluconate dehydrogenase,
NAD-binding; n=4; Burkholderia|Rep: 6-phosphogluconate
dehydrogenase, NAD-binding - Burkholderia phytofirmans
PsJN
Length = 297
Score = 89.4 bits (212), Expect = 1e-16
Identities = 67/202 (33%), Positives = 91/202 (45%), Gaps = 4/202 (1%)
Frame = +3
Query: 174 TDKNVAFLGLGNMGGFMAANLVKKGFTVRGYDPSKD---ALNAAAKNGVTPANSIXXXXX 344
T + F GLG MG MA L G +R ++ S + AL A+A N V S
Sbjct: 2 TSARLGFCGLGKMGWPMAQRLADAGHALRVWNRSNEKAAALQASATNCVA-CESPAQVAA 60
Query: 345 XXXXXXSILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEK-GLG 521
L V V G DG+ A++G+ L+D ST+ P+ + E+ G
Sbjct: 61 GAGIVMLCLADAAAVEAVAFGVDGLANRARRGATLVDHSTLAPSQTRAFARRWREQTGGD 120
Query: 522 FTDAPVSGGVMGAQNATLAFMAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNN 701
+ DAPVSGG GA TLA MAGG E P+L+ A+ G G+GQ KL N
Sbjct: 121 WIDAPVSGGTSGAAAGTLAIMAGGDATLIETLTPILRGYAARVTRMGGSGAGQATKLANQ 180
Query: 702 MLMGITGMAXAECMXMGIKMGL 767
++ T A AE + G+
Sbjct: 181 TIVMTTIAALAEATRLARHAGI 202
>UniRef50_A6VLT0 Cluster: 2-hydroxy-3-oxopropionate reductase; n=2;
Pasteurellaceae|Rep: 2-hydroxy-3-oxopropionate reductase
- Actinobacillus succinogenes 130Z
Length = 289
Score = 89.0 bits (211), Expect = 1e-16
Identities = 56/212 (26%), Positives = 104/212 (49%)
Frame = +3
Query: 180 KNVAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGVTPANSIXXXXXXXXXX 359
+ V ++GLG MG MAA+L++ G V Y+ + + A G + +S+
Sbjct: 7 REVGWIGLGQMGEPMAAHLLEHGVKVGVYNRTAEKCQNVAAKGASVYSSVLELVKAYDVI 66
Query: 360 XSILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAPV 539
++ ++ V++ L ++ V A KG L+++ ST+ P +Q+ + + G F +APV
Sbjct: 67 F-VMVADFPVIESLLSEE--VLTALKGKLVVNMSTVSPTQNQQLEFLLAKHGAEFIEAPV 123
Query: 540 SGGVMGAQNATLAFMAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMGIT 719
SG A+ L +A G++E E+ PL + F+ G++G KL N L+GI
Sbjct: 124 SGSSKVAEAGKLLVLAAGKEEIVEQLKPLFAAFSTQTFYYGEVGKAGGVKLMINSLLGIF 183
Query: 720 GMAXAECMXMGIKMGLXPKVLLDVLNNSSXRS 815
A E + + G+ ++++++ S S
Sbjct: 184 IQAYGEALLFAEQFGIPKDQVIEMISGSFMNS 215
>UniRef50_A6F020 Cluster: Putative uncharacterized protein; n=1;
Marinobacter algicola DG893|Rep: Putative
uncharacterized protein - Marinobacter algicola DG893
Length = 286
Score = 89.0 bits (211), Expect = 1e-16
Identities = 57/203 (28%), Positives = 96/203 (47%)
Frame = +3
Query: 186 VAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGVTPANSIXXXXXXXXXXXS 365
V+ +G+G+MG +A ++ KG V YD S++ + AKNG+ S+
Sbjct: 3 VSIIGVGDMGRDIAVHVRDKGHDVIAYDISEERRSDVAKNGIKVVESLAEAVAKAEVHLV 62
Query: 366 ILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAPVSG 545
I+ +++ V ++ GS ++ +T P + + +KGLGF DAPV
Sbjct: 63 IVATDEQSETV---TREILESGPAGSTVVILATNSPKTMQVLAAECEDKGLGFVDAPVVF 119
Query: 546 GVMGAQNATLAFMAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMGITGM 725
G GA+ L + GG + + P+L+ H G +GSGQVAK NNML +
Sbjct: 120 GRQGAKEGQLGSLCGGDDKQVAKITPVLESYSKAVHHVGPVGSGQVAKACNNMLHWAACV 179
Query: 726 AXAECMXMGIKMGLXPKVLLDVL 794
A E + + + G+ + + + L
Sbjct: 180 ANFEVLSLAKRYGIDAQQMRETL 202
>UniRef50_Q3W9L4 Cluster: Putative uncharacterized protein; n=1;
Frankia sp. EAN1pec|Rep: Putative uncharacterized
protein - Frankia sp. EAN1pec
Length = 294
Score = 88.6 bits (210), Expect = 2e-16
Identities = 61/208 (29%), Positives = 93/208 (44%), Gaps = 1/208 (0%)
Frame = +3
Query: 186 VAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGVTPANSIXXXXXXXXXXXS 365
V F+GLG+ GG MA + +G+ + + ++ A + GV S
Sbjct: 18 VGFIGLGSQGGPMARRIADEGYPLTIW--ARRAASVEPLAGVAAVASTPAEVGESSDVVG 75
Query: 366 I-LTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAPVS 542
I + ++ V DV L DGV+A G +++ STI P +++ A ++ + DAPVS
Sbjct: 76 ICVVADADVEDVLLRADGVLAGMAAGGVVVIHSTIRPETCQRLATEAAKQEISIIDAPVS 135
Query: 543 GGVMGAQNATLAFMAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMGITG 722
GG A L M GG + R P+L+ H G +GSGQVAKL NN +
Sbjct: 136 GGGDAAAQRRLLVMVGGEDDAVARCRPVLETFACPVIHLGPLGSGQVAKLVNNFVFTAQV 195
Query: 723 MAXAECMXMGIKMGLXPKVLLDVLNNSS 806
E ++G+ VL + S
Sbjct: 196 GLALETFSFAQRLGMDRAAAAQVLAHGS 223
>UniRef50_A6G049 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=1;
Plesiocystis pacifica SIR-1|Rep: 3-hydroxyisobutyrate
dehydrogenase - Plesiocystis pacifica SIR-1
Length = 307
Score = 88.6 bits (210), Expect = 2e-16
Identities = 59/222 (26%), Positives = 97/222 (43%), Gaps = 12/222 (5%)
Frame = +3
Query: 186 VAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAK-----------NGVTPANSIX 332
+AFLG G MG M NL G +R Y+ +K AAA V +
Sbjct: 4 IAFLGTGTMGAGMVRNLAAAGHELRIYNRTKSRAEAAADVVADTVDLSSGGSVRVVDEPV 63
Query: 333 XXXXXXXXXXSILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEK 512
+ + S+ V LG+ G +A +G+L+ID T + +Q+ +
Sbjct: 64 YAARGAEFIIACVGSDAATFAVLLGEGGALAGVGQGALVIDCGTTSLKLTEQLAAACEGE 123
Query: 513 GLGFTDAPVSGGVMGAQNATLAFMAGGRKEDFERSLPLLKVMGAKQFHCGQ-IGSGQVAK 689
G F DAP++G +GA+ L M G +E R++PL ++MG H + +G GQ AK
Sbjct: 124 GASFLDAPITGSKLGAEGGKLTIMVAGEEEIVARAMPLFEIMGKHTVHVSERLGDGQRAK 183
Query: 690 LTNNMLMGITGMAXAECMXMGIKMGLXPKVLLDVLNNSSXRS 815
NM + E + + + + ++L NS+ ++
Sbjct: 184 YCLNMTQAVVLQGLLEGYTLAKLLDVPLTKMAEILENSAGKT 225
>UniRef50_Q12H32 Cluster: 6-phosphogluconate dehydrogenase,
NAD-binding precursor; n=1; Polaromonas sp. JS666|Rep:
6-phosphogluconate dehydrogenase, NAD-binding precursor
- Polaromonas sp. (strain JS666 / ATCC BAA-500)
Length = 297
Score = 88.2 bits (209), Expect = 2e-16
Identities = 63/218 (28%), Positives = 102/218 (46%), Gaps = 6/218 (2%)
Frame = +3
Query: 180 KNVAFLGL-GNMGGFMAANLVKKGFTV-----RGYDPSKDALNAAAKNGVTPANSIXXXX 341
K++ +G G MG +A NL KGF + R + D L A AK +PA
Sbjct: 2 KHIGMIGASGLMGHGIARNLQAKGFDLSLTVHRNTERVADLLAAGAKQVASPAG-----L 56
Query: 342 XXXXXXXSILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLG 521
+T + V G DGV++ A G ++ID+ST +P +++ + E+G+
Sbjct: 57 GDCDAVIICVTGSPQVEQTLSGPDGVLSRALAGLIVIDTSTSEPESTRRLAALCAERGVT 116
Query: 522 FTDAPVSGGVMGAQNATLAFMAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNN 701
DAP++ + A+ L M G + F++ P+L FH G G+G V KL NN
Sbjct: 117 LVDAPLARTPVEAELGRLNTMVGAEQAVFDKIRPVLAAYCENIFHVGGPGAGHVIKLLNN 176
Query: 702 MLMGITGMAXAECMXMGIKMGLXPKVLLDVLNNSSXRS 815
+ A AE +G G+ P+ L++V++ + S
Sbjct: 177 FIGQAICTATAEAFAVGALAGINPQKLVEVISAGAVNS 214
>UniRef50_A2C1U6 Cluster: 3-hydroxyisobutyrate dehydrogenase and
related beta-hydroxyacid dehydrogenases; n=2;
Prochlorococcus marinus|Rep: 3-hydroxyisobutyrate
dehydrogenase and related beta-hydroxyacid
dehydrogenases - Prochlorococcus marinus (strain NATL1A)
Length = 287
Score = 87.0 bits (206), Expect = 6e-16
Identities = 59/211 (27%), Positives = 95/211 (45%)
Frame = +3
Query: 186 VAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGVTPANSIXXXXXXXXXXXS 365
+AF+GLG +G M+ L+ G+ + Y +K ++ K P ++
Sbjct: 3 LAFIGLGAIGKPMSQRLIDNGYDLNLYQRNKLNNDSKRKYFFDPIEAVSDCDGLLIC--- 59
Query: 366 ILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAPVSG 545
+T + V V G +GV K S +ID STI P+ I E+ + + D PVSG
Sbjct: 60 -VTDDNAVESVLFGDNGVSGSLKPNSFVIDFSTISPDKSISIHKRLGEQNIFYVDCPVSG 118
Query: 546 GVMGAQNATLAFMAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMGITGM 725
G GA N +L+ G ++D + +V+G + +G GQ K N +L+ T
Sbjct: 119 GTEGAHNGSLSLFIGASEKDCLSFENIFQVLGKSINYFNGVGKGQQVKALNQILVAGTYA 178
Query: 726 AXAECMXMGIKMGLXPKVLLDVLNNSSXRSW 818
A AE M +G + L ++ L + SW
Sbjct: 179 AVAEAMELGKMLELPMDDVVAALKVGAANSW 209
>UniRef50_Q0C8I2 Cluster: Predicted protein; n=3;
Pezizomycotina|Rep: Predicted protein - Aspergillus
terreus (strain NIH 2624)
Length = 320
Score = 86.2 bits (204), Expect = 1e-15
Identities = 72/222 (32%), Positives = 104/222 (46%), Gaps = 13/222 (5%)
Frame = +3
Query: 165 SSNTDKNVAFLGLGNMGGFMAANLVKK---GFTVRGYDPSKDALN---AAAKNGVTPANS 326
SS + ++ F+GLG MG MA L+ + +D + A+N A + S
Sbjct: 2 SSLSSDDIGFIGLGAMGLPMAQQLIANVPAPTRLYVFDIADQAMNDFVAMYPHKAVAGKS 61
Query: 327 IXXXXXXXXXXXSILTSNKVVLDVYLGKD-GVVAHAKKGSLLIDSSTIDP--NVPKQIFP 497
+++ V VYL + GV + LLID STID ++ +
Sbjct: 62 PRDVAEHSKTIITMVPEGSHVRAVYLDESTGVCSTPLDTRLLIDCSTIDTATSLAVKAHI 121
Query: 498 IALEKGLGFTDAPVSGGVMGAQNATLAFMAGGRKEDFERSLPLL----KVMGAKQFHCGQ 665
F DAPVSGGV+GAQ +AF G K D +LPLL ++MG + CG
Sbjct: 122 TTHHASASFYDAPVSGGVLGAQKGAIAFFLGCAKTD--PNLPLLTDTLRLMGKEVIPCGG 179
Query: 666 IGSGQVAKLTNNMLMGITGMAXAECMXMGIKMGLXPKVLLDV 791
G AKL NN L G+ +A +E + +G++ GL P+VL V
Sbjct: 180 PSLGLSAKLCNNYLSGLIAIANSEALNIGMRAGLDPRVLSSV 221
>UniRef50_Q1EPJ1 Cluster: 6-phosphogluconate dehydrogenase
NAD-binding domain-containing protein; n=8;
Magnoliophyta|Rep: 6-phosphogluconate dehydrogenase
NAD-binding domain-containing protein - Musa acuminata
(Banana)
Length = 314
Score = 85.0 bits (201), Expect = 2e-15
Identities = 64/214 (29%), Positives = 101/214 (47%), Gaps = 4/214 (1%)
Frame = +3
Query: 186 VAFLGLGNMGGFMAANLVKKGFTVRGY--DPSK-DALNAAAKNGV-TPANSIXXXXXXXX 353
V ++G G MG MAA L G+ V Y PSK D L + V +PA++
Sbjct: 18 VGWIGAGVMGAAMAARLQTAGYAVAIYARTPSKADHLRRLGAHLVPSPADAARSADVLFT 77
Query: 354 XXXSILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDA 533
+ +LD G +A G +L+D ++ DP + +++ A +G DA
Sbjct: 78 MVGHPFDVREALLDP---ASGALAAIPPGGVLVDCTSSDPALAREVAAAARARGCWAVDA 134
Query: 534 PVSGGVMGAQNATLAFMAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMG 713
PVSGG +GA++ TLA +AGG + PL + +G + G GSGQ +K+ N + +G
Sbjct: 135 PVSGGDVGARDGTLAILAGGDEGVVHWLSPLFEALGRATW-MGPAGSGQSSKIANQITIG 193
Query: 714 ITGMAXAECMXMGIKMGLXPKVLLDVLNNSSXRS 815
T + +E + + GL LD + + S
Sbjct: 194 GTILGLSEAIVFAGRAGLDVPRFLDAVRGGAAGS 227
>UniRef50_Q74D68 Cluster: 3-hydroxyisobutyrate dehydrogenase family
protein; n=7; Desulfuromonadales|Rep:
3-hydroxyisobutyrate dehydrogenase family protein -
Geobacter sulfurreducens
Length = 288
Score = 84.6 bits (200), Expect = 3e-15
Identities = 61/212 (28%), Positives = 87/212 (41%)
Frame = +3
Query: 180 KNVAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGVTPANSIXXXXXXXXXX 359
+ V FLGLG +G MAANL+K + + YD A+ A G T A +
Sbjct: 3 RKVGFLGLGTVGRHMAANLLKGNYELAVYDSDPAAVADLAALGATGAATPREVAKGRDIV 62
Query: 360 XSILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAPV 539
I + + G DG+ A G++L+D T ++ A + + F DAPV
Sbjct: 63 IHIRPEKERLRPDIYGPDGIFAGIDPGTILVDMGTHSLTSTMEMADEAAKHRVMFLDAPV 122
Query: 540 SGGVMGAQNATLAFMAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMGIT 719
G A N L +AGG R L G H G IG K N++
Sbjct: 123 WGTKEHAANGLLTILAGGDPSLVGRCRELFSFFGLNIIHVGSIGDATRMKFVVNLVQAEL 182
Query: 720 GMAXAECMXMGIKMGLXPKVLLDVLNNSSXRS 815
A AE + G K+G +L+VL++ S
Sbjct: 183 MQALAESIVFGEKLGFTADRILEVLDSGGVAS 214
>UniRef50_Q1GF31 Cluster: 6-phosphogluconate dehydrogenase
NAD-binding; n=17; Proteobacteria|Rep:
6-phosphogluconate dehydrogenase NAD-binding -
Silicibacter sp. (strain TM1040)
Length = 325
Score = 84.6 bits (200), Expect = 3e-15
Identities = 53/211 (25%), Positives = 89/211 (42%)
Frame = +3
Query: 186 VAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGVTPANSIXXXXXXXXXXXS 365
+ F+GLGN+GG +A +L++ GF + YD + D + + G P +
Sbjct: 3 IGFIGLGNVGGKLAGSLLRNGFDLTVYDLNPDLVAEYVEKGAQPGTGPLAIMRACDAVIT 62
Query: 366 ILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAPVSG 545
L S V + ++ + ++ ST D K++ + E+G + PVSG
Sbjct: 63 CLPSPAACATVV---EEMLPAVDSSKIWMEMSTTDAAEVKRLAALVSERGGSAMECPVSG 119
Query: 546 GVMGAQNATLAFMAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMGITGM 725
G A ++ AG + FER LP L +G + H G IGS + K+ N L +
Sbjct: 120 GCHRADTGNISIFAGCDRATFERMLPTLTTLGRRVLHTGDIGSASILKVMTNYLATANLL 179
Query: 726 AXAECMXMGIKMGLXPKVLLDVLNNSSXRSW 818
E + G+ + + SS S+
Sbjct: 180 TCCEALVTMKAAGIDLNTTYEAMKISSGTSF 210
>UniRef50_UPI0001597301 Cluster: YfjR; n=1; Bacillus
amyloliquefaciens FZB42|Rep: YfjR - Bacillus
amyloliquefaciens FZB42
Length = 286
Score = 83.8 bits (198), Expect = 5e-15
Identities = 56/203 (27%), Positives = 95/203 (46%), Gaps = 1/203 (0%)
Frame = +3
Query: 186 VAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGVTPANSIXXXXXXXXXXXS 365
+A +GLGNMG +A N++K G+++ Y+ +K+ G A + S
Sbjct: 3 IAIVGLGNMGRPIAENIMKAGYSLTVYNRTKEKAADLLDKGAEYAETPRQAAEHADIVLS 62
Query: 366 ILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAPVSG 545
+L+ + V DV G G++A + + I STI + +Q+ +G F APV G
Sbjct: 63 MLSDDDAVTDVTFGACGIIAGLSENGIHISMSTISTALSEQLSAAHSGRGQSFIAAPVLG 122
Query: 546 GVMGAQNATLAFMAGGRKEDFERSLPLLKVMGAKQFHCG-QIGSGQVAKLTNNMLMGITG 722
A+ A L + G E +++ PLL ++ + F G + + AK++ N L+
Sbjct: 123 RPDAAEKAELRIITAGPAEAKKKAEPLLNILSQQVFDTGEETKTANAAKISVNFLLVSML 182
Query: 723 MAXAECMXMGIKMGLXPKVLLDV 791
A +E M K GL K L++
Sbjct: 183 EALSESFLMMEKYGLEQKQFLEI 205
>UniRef50_Q9HLR4 Cluster: Putative uncharacterized protein Ta0161;
n=2; Thermoplasma|Rep: Putative uncharacterized protein
Ta0161 - Thermoplasma acidophilum
Length = 290
Score = 83.8 bits (198), Expect = 5e-15
Identities = 65/214 (30%), Positives = 94/214 (43%), Gaps = 2/214 (0%)
Frame = +3
Query: 180 KNVAFLGLGNMGGFMAANLVKKGFTVRGYDPSKD-ALNAAAKNGVTPANSIXXXXXXXXX 356
K V +GLG MG +AAN G YD + D A N A+ V +
Sbjct: 8 KKVLLVGLGVMGSRIAANFASAGKLAGVYDRNVDKAKNTASMLKVGFYRDLGEAVKNSDI 67
Query: 357 XXSILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAP 536
++L ++ V +VY + V +G + ID STI P+ +I EKG DAP
Sbjct: 68 IVTMLYDDRSVKEVYSQMEQGV----QGKVFIDMSTISPDTSIEIAKRIKEKGGKMYDAP 123
Query: 537 VSGGVMGAQNATLAFMAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMGI 716
V G + + L + GG ++ L+ + + G GSG AKL NN+ +G
Sbjct: 124 VIGTSIAVEKKALVVLVGGDLSGYDEVRDLISATANQVVYMGDNGSGLYAKLVNNLFLGS 183
Query: 717 TGMAXAECMXMGIKMGLXPKVLLDVLNN-SSXRS 815
+ AE + G K G+ + DVL SS RS
Sbjct: 184 YMASLAEAVRFGRKNGIPDSTISDVLTKYSSARS 217
>UniRef50_A3EW86 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=1;
Leptospirillum sp. Group II UBA|Rep:
3-hydroxyisobutyrate dehydrogenase - Leptospirillum sp.
Group II UBA
Length = 279
Score = 83.0 bits (196), Expect = 9e-15
Identities = 60/200 (30%), Positives = 96/200 (48%), Gaps = 2/200 (1%)
Frame = +3
Query: 210 MGGFMAANLVKKGFTVRGYDPSKDAL--NAAAKNGVTPANSIXXXXXXXXXXXSILTSNK 383
MG M L+ G V GY+ + L + TPA+ I + ++++
Sbjct: 1 MGVRMVRRLLDNGIPVTGYNRTAGRLPSHPLFHAAHTPAD-IAEKSDLIFLMVTDGSASR 59
Query: 384 VVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAPVSGGVMGAQ 563
+L+ G DG+ + GSL+I+ STI P ++ L KG G+ D PVSG ++ A+
Sbjct: 60 ALLE---GPDGIARGLRPGSLVINMSTIAPEEAQEEALSLLAKGAGYLDVPVSGSLVPAE 116
Query: 564 NATLAFMAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMGITGMAXAECM 743
L +AGG ER+ P+L G K H G GSG AKL N+L+ + + +
Sbjct: 117 KGELLLLAGGDGAALERARPILLHFGKKILHFGPTGSGMKAKLVINLLLASHVESLVQTV 176
Query: 744 XMGIKMGLXPKVLLDVLNNS 803
+G +GL +L ++ +S
Sbjct: 177 LVGESLGLDGHQVLGMILDS 196
>UniRef50_A7H7Z5 Cluster: 6-phosphogluconate dehydrogenase
NAD-binding; n=2; Anaeromyxobacter|Rep:
6-phosphogluconate dehydrogenase NAD-binding -
Anaeromyxobacter sp. Fw109-5
Length = 293
Score = 82.6 bits (195), Expect = 1e-14
Identities = 63/212 (29%), Positives = 92/212 (43%), Gaps = 2/212 (0%)
Frame = +3
Query: 186 VAFLGLGNMGGFMAANLVKKG--FTVRGYDPSKDALNAAAKNGVTPANSIXXXXXXXXXX 359
+ F+GLG +G +A NL K G TV PSK A + +K G A S
Sbjct: 5 IGFVGLGTIGEPIANNLRKAGHDLTVWNRTPSK-AAHIVSKGGKL-AGSARECATGRDLV 62
Query: 360 XSILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAPV 539
+ ++ K + V G DGV+ + G +L+D ST + + A +G GF PV
Sbjct: 63 ITCVSDEKALDTVLEGPDGVLEALRDGDVLVDMSTAGVRAARSVSERAAARGAGFVACPV 122
Query: 540 SGGVMGAQNATLAFMAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMGIT 719
G A+ A L +AGG ER+ P L + A+ F + KL N + G
Sbjct: 123 LGSRSAAEQAQLVLVAGGPAVARERARPALHAVSARIFELEDAAQAALMKLCVNAIGGAM 182
Query: 720 GMAXAECMXMGIKMGLXPKVLLDVLNNSSXRS 815
E + +G G+ L++VL SS S
Sbjct: 183 ITGFGEALALGQAGGVPVAKLVEVLQASSFHS 214
>UniRef50_A6RMW8 Cluster: Putative uncharacterized protein; n=2;
Sclerotiniaceae|Rep: Putative uncharacterized protein -
Botryotinia fuckeliana B05.10
Length = 446
Score = 82.6 bits (195), Expect = 1e-14
Identities = 70/227 (30%), Positives = 107/227 (47%), Gaps = 10/227 (4%)
Frame = +3
Query: 168 SNTDKN-VAFLGLGNMGGFMAANLVKKGFTVRG---YDPSKDALNAAAKNGVTPANSIXX 335
S++DK VAF+GLG MG MA NL+K F+V G Y+P+ + +A N T S
Sbjct: 2 SSSDKPAVAFIGLGAMGMGMATNLLKT-FSVTGFDVYEPTLEKFRSAGGNTATTPRS--A 58
Query: 336 XXXXXXXXXSILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDP-NVP--KQIFPIAL 506
+ T+ + + ++ G + + + +I SST P +VP +++
Sbjct: 59 VANAQYIVIMVATAAQTLAVLFDDVTGAIHELQPNATIILSSTAFPEHVPEVRELLDNKY 118
Query: 507 -EKGLGFTDAPVSGGVMGAQNATLAFMAGGRKEDFERSLPLLKVMGAKQFHC--GQIGSG 677
K + DAPVSGG A TL +A G ++ + + P+L M A H G +G+G
Sbjct: 119 NRKDVELVDAPVSGGTSRAALGTLVILASGPEKSLDAAKPVLDAM-ADPLHMIPGGLGAG 177
Query: 678 QVAKLTNNMLMGITGMAXAECMXMGIKMGLXPKVLLDVLNNSSXRSW 818
K+ + L GI + +E M +GL K D L SS SW
Sbjct: 178 TKVKMVHQALAGIHMIMASEAMGFAAFLGLNTKQAFDYLVKSSGESW 224
>UniRef50_A7DWL2 Cluster: Putative dehydrogenase; n=1; Streptomyces
tendae|Rep: Putative dehydrogenase - Streptomyces tendae
Length = 293
Score = 82.2 bits (194), Expect = 2e-14
Identities = 59/210 (28%), Positives = 90/210 (42%)
Frame = +3
Query: 186 VAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGVTPANSIXXXXXXXXXXXS 365
VA +GLG MG MA L++ GF V ++ S AA+ G A S
Sbjct: 5 VAVIGLGGMGSGMALALLRAGFQVTVFNRSPQKAEQAARAGAAVAPSAGAAGAAARVVLL 64
Query: 366 ILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAPVSG 545
L V +V G+ VV + G++L+D++T+ P+ + G+ +A V G
Sbjct: 65 SLADEPAVDEVLFGE--VVWQLQPGTVLVDTTTVSPSFARNTAVRLAASGVERLEACVMG 122
Query: 546 GVMGAQNATLAFMAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMGITGM 725
A++ L G + + +L +G + H G G KL N+L+GI
Sbjct: 123 NPEMAESGRLRIFTSGSHSAVDAAGDVLSALGQEVRHLGDAGRASALKLALNLLLGIQTA 182
Query: 726 AXAECMXMGIKMGLXPKVLLDVLNNSSXRS 815
AE + GL +LL+VL S RS
Sbjct: 183 GLAEAVAFAEAAGLGRDLLLEVLLGSGWRS 212
>UniRef50_A5WG80 Cluster: 6-phosphogluconate dehydrogenase,
NAD-binding; n=2; Moraxellaceae|Rep: 6-phosphogluconate
dehydrogenase, NAD-binding - Psychrobacter sp. PRwf-1
Length = 309
Score = 82.2 bits (194), Expect = 2e-14
Identities = 65/218 (29%), Positives = 95/218 (43%)
Frame = +3
Query: 183 NVAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGVTPANSIXXXXXXXXXXX 362
+V+F+GLG MG MA +LV TV Y+ + D A A T A S+
Sbjct: 17 SVSFIGLGAMGHHMAKHLVGSFDTVMVYNRNFDKATAHAAEFGTQAVSLEQAVSADVIF- 75
Query: 363 SILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAPVS 542
S L +++VV D+ + + H GS+ +D ++ P K G F DAPVS
Sbjct: 76 SCLPTSQVVDDLI---EQALPHLNDGSVWVDCTSGVPENAKASQAKLNAAGCEFLDAPVS 132
Query: 543 GGVMGAQNATLAFMAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMGITG 722
G GA + TL M GG + + + H G G+G K NN L I
Sbjct: 133 GQTSGADSGTLTVMVGGSAKALAYAKSAIDCFAGLIVHVGDSGAGFAVKAVNNTLFAINA 192
Query: 723 MAXAECMXMGIKMGLXPKVLLDVLNNSSXRSWSTXXVL 836
A E + + G+ P L +N +S +S++T L
Sbjct: 193 WAAVEGLSVLKAHGVNPSDALACINKASGQSFATLVTL 230
>UniRef50_A3Y8R5 Cluster: Putative dehydrogenase; n=1; Marinomonas
sp. MED121|Rep: Putative dehydrogenase - Marinomonas sp.
MED121
Length = 297
Score = 81.8 bits (193), Expect = 2e-14
Identities = 58/215 (26%), Positives = 99/215 (46%), Gaps = 4/215 (1%)
Frame = +3
Query: 186 VAFLGLGNMGGFMAANLVK----KGFTVRGYDPSKDALNAAAKNGVTPANSIXXXXXXXX 353
+ F+GLGNMG MAANL++ + D +++ ++ G A+S+
Sbjct: 3 IGFIGLGNMGSGMAANLLEYCKANHNELLVLDLNQEVVSQFVDKGARKADSVKHVAQECD 62
Query: 354 XXXSILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDA 533
+ L S+ V + G++G++ +A+ G+ ++ST + + +++ IA L DA
Sbjct: 63 VIFTSLPSSVQVNHIAFGEEGILENAQAGATWFETSTNELSEWEKVKAIA-PSHLSLIDA 121
Query: 534 PVSGGVMGAQNATLAFMAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMG 713
PV+GG GA TL + G ++ + +L G G+G V KL L
Sbjct: 122 PVTGGAEGAAAGTLTMLLGIDEQILTKFTSMLNAFTKNAIRMGPSGAGYVTKLAQLHLNY 181
Query: 714 ITGMAXAECMXMGIKMGLXPKVLLDVLNNSSXRSW 818
+ E + MG K L VL +L NS +S+
Sbjct: 182 LVAQGIGEALMMGAKAELNLDVLHKILQNSCAQSY 216
>UniRef50_Q7Q161 Cluster: ENSANGP00000013149; n=11; Culicidae|Rep:
ENSANGP00000013149 - Anopheles gambiae str. PEST
Length = 581
Score = 81.8 bits (193), Expect = 2e-14
Identities = 54/208 (25%), Positives = 91/208 (43%)
Frame = +3
Query: 192 FLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGVTPANSIXXXXXXXXXXXSIL 371
FLGLG MG + NL+K G +V ++ S + G A++ S +
Sbjct: 300 FLGLGVMGCGIVKNLIKSGHSVVVWNRSAHKCRKFQEVGAEVADTPSDVVEMTDVTYSCV 359
Query: 372 TSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAPVSGGV 551
+ +V D+ G GV++ G ++ + +DP I + KG + +A + G
Sbjct: 360 SDPQVAKDMVFGNCGVMSANLAGKGYVEMTGVDPETSNDINEAIISKGGRYLEAQIQGSK 419
Query: 552 MGAQNATLAFMAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMGITGMAX 731
A+ TL +A G + FE + + F+ G +G+ L M+ GIT
Sbjct: 420 NQAEEGTLIILASGDRLLFEECQSCFEAISRNSFYLGDVGNATKMNLILQMISGITLAGV 479
Query: 732 AECMXMGIKMGLXPKVLLDVLNNSSXRS 815
AE M + + GL K +L+VL ++ S
Sbjct: 480 AEAMALADRAGLQQKDVLEVLELTNMSS 507
>UniRef50_A3LTC4 Cluster: 3-hydroxyisobutyrate dehydrogenase-like
protein; n=6; Saccharomycetales|Rep:
3-hydroxyisobutyrate dehydrogenase-like protein - Pichia
stipitis (Yeast)
Length = 355
Score = 81.8 bits (193), Expect = 2e-14
Identities = 79/271 (29%), Positives = 124/271 (45%), Gaps = 30/271 (11%)
Frame = +3
Query: 138 LYTAAR---RAYSSNT--DKNVAFLGLGNMGGFMAANLVKK-------------GFTVRG 263
+Y A+R R +SS + + F+GLG MG MA ++ K +
Sbjct: 1 MYKASRICTRHFSSTSMASTSYGFIGLGQMGQHMARHIYNKLEATDKLYVNDNVAAATQS 60
Query: 264 YDPSKDALNAAAKNGVTPANSIXXXXXXXXXXXS-ILTSNKVVLDVYLGKDGVVAHAKKG 440
+ + N A K+ + P NS+ I+T V +V+H +K
Sbjct: 61 FIKNVTDENPANKDALKPLNSLEEFVTSVDEPLDFIITMVPEGKHVKGVVSELVSHYQKN 120
Query: 441 SL------LIDSSTIDPNVPKQIFPIALEK--GLGFTDAPVSGGVMGAQNATLAFM-AGG 593
++ +DSSTID +++ ++ G F D PVSGGV GA+ ATL+FM +
Sbjct: 121 NVSGTKTTFLDSSTIDIPTSREVHEFVKKELPGADFIDTPVSGGVAGARKATLSFMLSRP 180
Query: 594 RKEDFERSL-PLLKVMGAKQFHCGQI-GSGQVAKLTNNMLMGITGMAXAECMXMGIKMGL 767
E L LL MGA F CG+ G+G AKL+NN L+ +T +A A+ + GL
Sbjct: 181 NNESISADLRTLLNKMGANIFACGETHGAGLAAKLSNNYLLAVTNLAVADSFQLAKSFGL 240
Query: 768 XPKVLLDVLNNSSXRSWSTXXVLSXPRTGAH 860
K +++ S+ + W+ V + P GA+
Sbjct: 241 NLKDYAKLVSVSTGKCWAA--VDNCPIPGAY 269
>UniRef50_Q5LNV6 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=2;
Rhodobacteraceae|Rep: 3-hydroxyisobutyrate dehydrogenase
- Silicibacter pomeroyi
Length = 269
Score = 81.0 bits (191), Expect = 4e-14
Identities = 57/211 (27%), Positives = 90/211 (42%)
Frame = +3
Query: 186 VAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGVTPANSIXXXXXXXXXXXS 365
+ G G MG M A L + GF +G+D + +G+T + + +
Sbjct: 2 IGVAGCGRMGAPMLAALRRAGFQAQGFDIRPSSDFPGTDHGIT--DGVAVFSQNLCTLIT 59
Query: 366 ILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAPVSG 545
++ V L D + HAK +I ST+ P + + + + DAP+SG
Sbjct: 60 VVRDISQTEQV-LFTDQKLIHAKHLDCVIICSTLSPRYVRDL-RARVPDHIALIDAPMSG 117
Query: 546 GVMGAQNATLAFMAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMGITGM 725
+ AQ A L+FM GG D + + PL MG+ G GSG AK+ NN+L
Sbjct: 118 AQIAAQEARLSFMLGGEPADLDAAQPLFAAMGSHFHRMGPYGSGMQAKVLNNLLAAANTA 177
Query: 726 AXAECMXMGIKMGLXPKVLLDVLNNSSXRSW 818
+ GL LL +++ SS ++W
Sbjct: 178 MTRLVLDWADAAGLDEVALLRLIHTSSGQNW 208
>UniRef50_Q3WJ00 Cluster: 6-phosphogluconate dehydrogenase, NAD
binding domain; n=1; Frankia sp. EAN1pec|Rep:
6-phosphogluconate dehydrogenase, NAD binding domain -
Frankia sp. EAN1pec
Length = 438
Score = 81.0 bits (191), Expect = 4e-14
Identities = 61/216 (28%), Positives = 86/216 (39%)
Frame = +3
Query: 159 AYSSNTDKNVAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGVTPANSIXXX 338
+Y F+GLG+MG MA L +G + Y +L A T A +
Sbjct: 163 SYHDEDTVKTGFIGLGSMGLPMAQRLQSQGHDLTLYARRPASLEPFAGTSATIAATPAEM 222
Query: 339 XXXXXXXXSILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGL 518
+ V +V G DG+ G++++ ST+ P ++I A GL
Sbjct: 223 GASVDAVGICVFDAAGVEEVMFGPDGLAGTLNPGAVVLVHSTVAPAQIRRIAGRAATHGL 282
Query: 519 GFTDAPVSGGVMGAQNATLAFMAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTN 698
DAPVSGG A L M GG + LL + H G +G+G AKL N
Sbjct: 283 RVLDAPVSGGQPRALAGELTIMIGGDADTLADVAELLSALSNHVVHLGAVGAGSYAKLIN 342
Query: 699 NMLMGITGMAXAECMXMGIKMGLXPKVLLDVLNNSS 806
N + + M G +G+ P L VL SS
Sbjct: 343 NTMFAAQIALADDAMKAGESLGIDPAGLAAVLATSS 378
>UniRef50_A7RG59 Cluster: Predicted protein; n=1; Nematostella
vectensis|Rep: Predicted protein - Nematostella
vectensis
Length = 341
Score = 80.6 bits (190), Expect = 5e-14
Identities = 61/236 (25%), Positives = 104/236 (44%)
Frame = +3
Query: 111 ARTILSTQCLYTAARRAYSSNTDKNVAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALN 290
AR + L+ AA +S + + V +G GN+G +A L K +V+ +D ++ N
Sbjct: 4 ARFLARNAFLWRAAFSMSTSASPRTVGLVGTGNVGSAVAVGLRKIDVSVKAFDLQQNNYN 63
Query: 291 AAAKNGVTPANSIXXXXXXXXXXXSILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTID 470
G T NS + L + V L G+++ K+GS+ ID +T D
Sbjct: 64 FLESTGTTLVNSPEEVTKDVDVLITALPKPQHVKSA-LEDTGMLSMLKEGSVWIDHTTTD 122
Query: 471 PNVPKQIFPIALEKGLGFTDAPVSGGVMGAQNATLAFMAGGRKEDFERSLPLLKVMGAKQ 650
N ++ +A KG+ +AP++GG + GG ++ + PL+ A
Sbjct: 123 YNETIRLGELATSKGVHAVEAPLTGG-----QGLMTVFVGGEEKVVQDVKPLMDSYTATF 177
Query: 651 FHCGQIGSGQVAKLTNNMLMGITGMAXAECMXMGIKMGLXPKVLLDVLNNSSXRSW 818
+ G +G VAK+ +NML +A E + + K GL D + S+ S+
Sbjct: 178 LYFGPLGKATVAKVISNMLCAAHLVAAGEALMLAKKAGLDMSNFFDGIRYSAGNSY 233
>UniRef50_P71825 Cluster: Uncharacterized oxidoreductase
Rv0770/MT0794; n=18; Corynebacterineae|Rep:
Uncharacterized oxidoreductase Rv0770/MT0794 -
Mycobacterium tuberculosis
Length = 295
Score = 80.6 bits (190), Expect = 5e-14
Identities = 57/206 (27%), Positives = 87/206 (42%)
Frame = +3
Query: 186 VAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGVTPANSIXXXXXXXXXXXS 365
+ ++GLGN G MA L+ + +D +A+ + G T A S+ +
Sbjct: 10 LGYIGLGNQGAPMAKRLLDWPGGLTVFDVRVEAMAPFVEGGATAAASVSDVAEADIISIT 69
Query: 366 ILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAPVSG 545
+ +V V +G+ HAK G+++ STI + +G+ DAPVSG
Sbjct: 70 VFDDAQVS-SVITADNGLATHAKPGTIVAIHSTIADTTAVDLAEKLKPQGIHIVDAPVSG 128
Query: 546 GVMGAQNATLAFMAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMGITGM 725
G A LA M G E F+R + H G+ G+G KL NML ++
Sbjct: 129 GAAAAAKGELAVMVGADDEAFQRIKEPFSRWASLLIHAGEPGAGTRMKLARNMLTFVSYA 188
Query: 726 AXAECMXMGIKMGLXPKVLLDVLNNS 803
A AE + GL L V+ +S
Sbjct: 189 AAAEAQRLAEACGLDLVALGKVVRHS 214
>UniRef50_A0JRK4 Cluster: 6-phosphogluconate dehydrogenase,
NAD-binding precursor; n=3; Actinomycetales|Rep:
6-phosphogluconate dehydrogenase, NAD-binding precursor
- Arthrobacter sp. (strain FB24)
Length = 299
Score = 80.2 bits (189), Expect = 7e-14
Identities = 60/213 (28%), Positives = 99/213 (46%), Gaps = 2/213 (0%)
Frame = +3
Query: 186 VAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGVTPANSIXXXXXXXXXXXS 365
+ LGLG MG MA L + TV G+D ++ L A + G+ S
Sbjct: 7 ITVLGLGAMGLPMATRLASQ-LTVHGFDIAEPRLKLAEEAGIRTFASAREASEGADALLL 65
Query: 366 ILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPN-VPKQIFPIALEKGLGFTDAPVS 542
+ + + + DV G +GV + K G+++I ST+ + +P + +A E G+ DAP+S
Sbjct: 66 AVRNGEQLNDVLFGANGVASVLKPGAVVILGSTVGTDAIPATVDRLA-EYGVELVDAPLS 124
Query: 543 GGVMGAQNATLAFMAGGRKEDFERSLPLLKVMGAKQFHCG-QIGSGQVAKLTNNMLMGIT 719
GG A L + G E E++ P L+++ + G + G GQ K N +L G+
Sbjct: 125 GGPKRAGEGDLLIVVGASPEAQEKARPALELLASTLTVVGDKPGDGQALKTVNQLLCGVH 184
Query: 720 GMAXAECMXMGIKMGLXPKVLLDVLNNSSXRSW 818
A AE + + +GL + L L + S+
Sbjct: 185 IAAAAEALALADALGLDQEKTLKALEAGAAGSF 217
>UniRef50_A0R1N5 Cluster: 6-phosphogluconate dehydrogenase,
NAD-binding; n=3; Mycobacterium|Rep: 6-phosphogluconate
dehydrogenase, NAD-binding - Mycobacterium smegmatis
(strain ATCC 700084 / mc(2)155)
Length = 263
Score = 79.8 bits (188), Expect = 9e-14
Identities = 58/211 (27%), Positives = 87/211 (41%), Gaps = 1/211 (0%)
Frame = +3
Query: 186 VAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGVTP-ANSIXXXXXXXXXXX 362
+ FLG G MG M L G V + + A A +G TP A +
Sbjct: 3 IGFLGAGRMGAPMVQRLTAAGHDVHALGRTDEKRTAVAGSGATPVAAATDAVHGADVVIV 62
Query: 363 SILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAPVS 542
+ T +V L D ++ G++L+ +T P + I A ++G+ DAPVS
Sbjct: 63 CVFTDEQVRT---LCTDTLLDAMAPGAVLVLHTTGSPRTAEDIAARAADRGVAVVDAPVS 119
Query: 543 GGVMGAQNATLAFMAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMGITG 722
GG ++ AGG + ER P L H G +GSGQ KL NN +
Sbjct: 120 GGPHDIAAGSVTVFAGGDADVVERVRPALVAYAEPLLHVGPLGSGQRVKLVNNTMFAAQI 179
Query: 723 MAXAECMXMGIKMGLXPKVLLDVLNNSSXRS 815
AE + + ++G+ +L L + S S
Sbjct: 180 GVVAEGVRLARELGVDEPTVLSALTHGSAAS 210
>UniRef50_Q55JR1 Cluster: Putative uncharacterized protein; n=2;
Filobasidiella neoformans|Rep: Putative uncharacterized
protein - Cryptococcus neoformans (Filobasidiella
neoformans)
Length = 605
Score = 79.8 bits (188), Expect = 9e-14
Identities = 56/219 (25%), Positives = 101/219 (46%), Gaps = 8/219 (3%)
Frame = +3
Query: 186 VAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGVTPANSIXXXXXXXXXXXS 365
V ++GLG MG MAA+LV +G+ V+ +D +L A+ G P++S
Sbjct: 9 VGWIGLGAMGSGMAASLVSQGYKVQAFDVYPPSLKRVAEQGAIPSSSPRDAAEGVQVLCL 68
Query: 366 ILTSNKVVLDVYLGKDGVVAH-AKKGSLLIDSSTIDPNVPKQIFP--IALEKGLGFTDAP 536
++ + + V + GKDG VA K G+ +I ST+ P+ ++ L K +G D+P
Sbjct: 69 MVVNAQQVEETLFGKDGGVAEILKNGASIIVFSTVPPSFLVEVARRLDKLGKNIGLVDSP 128
Query: 537 VSGGVMGAQNATLAFMAGGRKEDFERSLPLLKVM-----GAKQFHCGQIGSGQVAKLTNN 701
VSGG A LA M+ G + +L + G ++G K+ N
Sbjct: 129 VSGGSTRAAQGQLAIMSSGTPSSIATARTVLDSLTLPPQGGLTLVGDRVGIASDFKMINQ 188
Query: 702 MLMGITGMAXAECMXMGIKMGLXPKVLLDVLNNSSXRSW 818
+ ++ A E + + +GL + + +++ ++ S+
Sbjct: 189 VFCAVSIAAQGEALGLAKALGLNVRTVYEIVKQTTGDSF 227
Score = 36.3 bits (80), Expect = 1.1
Identities = 31/115 (26%), Positives = 47/115 (40%), Gaps = 8/115 (6%)
Frame = +3
Query: 498 IALE-KGLGFTDAPVSGGVMGAQNATLAFMAGGRKEDFERS---LPLLKVMGAK----QF 653
+A+E K L DAP +GG A+ +L A G + S L L + G F
Sbjct: 411 LAIEIKPLQLIDAPTAGGSKEAKGGSLTVFASGEADALSASHSILSALSIQGGDPTKLHF 470
Query: 654 HCGQIGSGQVAKLTNNMLMGITGMAXAECMXMGIKMGLXPKVLLDVLNNSSXRSW 818
G +GS K N++L I E G+ + + VL+ + RS+
Sbjct: 471 IAGGVGSATKVKAVNSLLEAIHLAVTGEGFAFAKHKGMDIEKVFKVLSGGAARSF 525
>UniRef50_Q9RX16 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=6;
Bacteria|Rep: 3-hydroxyisobutyrate dehydrogenase -
Deinococcus radiodurans
Length = 310
Score = 79.4 bits (187), Expect = 1e-13
Identities = 61/209 (29%), Positives = 93/209 (44%)
Frame = +3
Query: 189 AFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGVTPANSIXXXXXXXXXXXSI 368
AFLGLG MG MAA+L + + G + A A++ A S +
Sbjct: 21 AFLGLGAMGFPMAAHLAAQAASGGGRALVWNRTEAKAQDHAARAGSEAVSLADTAQADVL 80
Query: 369 LTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAPVSGG 548
T +V + H + G++ +D ++ P+ ++ G+ F DAPVSGG
Sbjct: 81 FTCLPTSAEVDEIIAALSPHLRPGTVWVDCTSGHPDAARRQRETLDALGVKFLDAPVSGG 140
Query: 549 VMGAQNATLAFMAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMGITGMA 728
GA+ TL M GG ++ + + P L G K G+ G+G K NNML+ + A
Sbjct: 141 TSGAEAGTLTVMLGGPADEIDAASPHLAFAG-KVVRVGETGAGFAVKAVNNMLLAVNLWA 199
Query: 729 XAECMXMGIKMGLXPKVLLDVLNNSSXRS 815
E + + G+ L V+N SS RS
Sbjct: 200 AGEGLAALGRSGVDLGAALSVINASSGRS 228
>UniRef50_Q8F4I7 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=4;
Leptospira|Rep: 3-hydroxyisobutyrate dehydrogenase -
Leptospira interrogans
Length = 296
Score = 79.4 bits (187), Expect = 1e-13
Identities = 55/210 (26%), Positives = 95/210 (45%)
Frame = +3
Query: 186 VAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGVTPANSIXXXXXXXXXXXS 365
++ +G G MG MA NL K G ++R Y + + K+ V +S
Sbjct: 7 ISIIGTGIMGRGMAVNLAKAGHSLRLYTRNLSKIQDLKKDNVQIFDSPIEAAKNSDLVVL 66
Query: 366 ILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAPVSG 545
LT +++V + G++ K +LID T ++ ++ + EK + F D+P++G
Sbjct: 67 CLTEDQIVEKETISS-GLLD--TKPPILIDCGTTSLSLTLKLSKLCSEKKIRFYDSPMTG 123
Query: 546 GVMGAQNATLAFMAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMGITGM 725
A++ + FM G ++ D + +V G +CG IG GQ AKL NM+
Sbjct: 124 SKNAARDGQILFMIGAKQVDIKDIQFFFEVCGKNAVYCGSIGGGQKAKLALNMIQAGIFQ 183
Query: 726 AXAECMXMGIKMGLXPKVLLDVLNNSSXRS 815
E + L P +L ++L S+ +S
Sbjct: 184 VYMEGFELAKNSELDPSILKEILLQSAAKS 213
>UniRef50_A0YMN9 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=3;
Cyanobacteria|Rep: 3-hydroxyisobutyrate dehydrogenase -
Lyngbya sp. PCC 8106
Length = 371
Score = 79.4 bits (187), Expect = 1e-13
Identities = 55/211 (26%), Positives = 92/211 (43%), Gaps = 4/211 (1%)
Frame = +3
Query: 186 VAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGVTPANSIXXXXXXXXXXXS 365
+ +G GN+G AAN + G++V YD + + G +S +
Sbjct: 19 LGIIGCGNIGKRQAANFLAHGYSVYVYDINPARMAQLQSLGAHITHSCAELATHCEVIFT 78
Query: 366 IL-TSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAPV- 539
L T + + V G+ + + GS+ ID +T P ++ G+ D P
Sbjct: 79 ALPTPSDTIKAVLEGEQNLSQGLRSGSIYIDITTNSPETIHRLHQAISPLGVEMLDVPFN 138
Query: 540 --SGGVMGAQNATLAFMAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMG 713
S G LA +A G + FER PLL++M + +CG+IGSG KL +N +
Sbjct: 139 DCSEGATSEGGMGLAVLASGSRATFERVEPLLQLMADQVLYCGEIGSGTRCKLIHNAVNA 198
Query: 714 ITGMAXAECMXMGIKMGLXPKVLLDVLNNSS 806
+ A +E + +G+ G+ + + D L S
Sbjct: 199 VAVQAVSEGITLGLAQGISLETIWDTLRFGS 229
>UniRef50_Q98K09 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=7;
Alphaproteobacteria|Rep: 3-hydroxyisobutyrate
dehydrogenase - Rhizobium loti (Mesorhizobium loti)
Length = 312
Score = 79.0 bits (186), Expect = 2e-13
Identities = 57/209 (27%), Positives = 90/209 (43%), Gaps = 2/209 (0%)
Frame = +3
Query: 180 KNVAFLGLGNMGGFMAANLVKKGF--TVRGYDPSKDALNAAAKNGVTPANSIXXXXXXXX 353
+ + F+GLG MG +A N+V KG+ T G K A + + G A++
Sbjct: 8 EKIGFIGLGLMGHGIAKNIVDKGYPLTFLGRKNRKPAEDLLGR-GAREASTSRDVAVASD 66
Query: 354 XXXSILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDA 533
+T ++ V + G G+ KKGS+++D ST DP + G+ + DA
Sbjct: 67 IVFICVTGSREVEAIIRGPGGLKEGLKKGSVVVDCSTSDPVSTVALAAELKALGIDYVDA 126
Query: 534 PVSGGVMGAQNATLAFMAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMG 713
P+S A TL M G F R P+++ + H G G G KL NN +
Sbjct: 127 PLSRTPKEAWEGTLDAMVGAPDAVFARVKPVIETWAGRIVHIGDTGDGHRMKLLNNFISL 186
Query: 714 ITGMAXAECMXMGIKMGLXPKVLLDVLNN 800
+E + + K+G+ P V+ N
Sbjct: 187 GYAAIYSEALALAEKVGISPPRFDSVIRN 215
>UniRef50_A1UJF3 Cluster: 6-phosphogluconate dehydrogenase,
NAD-binding; n=4; Actinomycetales|Rep:
6-phosphogluconate dehydrogenase, NAD-binding -
Mycobacterium sp. (strain KMS)
Length = 272
Score = 78.6 bits (185), Expect = 2e-13
Identities = 58/211 (27%), Positives = 88/211 (41%), Gaps = 1/211 (0%)
Frame = +3
Query: 186 VAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGV-TPANSIXXXXXXXXXXX 362
V F+G G MG M LV G TV + + AA+ G T A +
Sbjct: 4 VGFVGAGRMGAPMVRRLVGAGHTVTALGRTPEKRAAASDLGAATAAEPVDVATGADIVVV 63
Query: 363 SILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAPVS 542
+ T ++V G G++A G+ L+ +T P+ + + + G+ DAPVS
Sbjct: 64 CVFTDDQVRAVCLDG--GLLAAMAPGATLVIHTTGSPDTARLLAARGRDHGVDVVDAPVS 121
Query: 543 GGVMGAQNATLAFMAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMGITG 722
GG + GG + ER+ P+L G H G +G+GQ KL NN +
Sbjct: 122 GGPHDIAAGAVTLFVGGSEAAVERARPVLAAYGDPILHVGPLGAGQSVKLVNNTVFAAQI 181
Query: 723 MAXAECMXMGIKMGLXPKVLLDVLNNSSXRS 815
E + +G +G+ LL L + S S
Sbjct: 182 GLLREAVRLGGALGVAEPDLLTALTHGSSSS 212
>UniRef50_A0RU56 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=1;
Cenarchaeum symbiosum|Rep: 3-hydroxyisobutyrate
dehydrogenase - Cenarchaeum symbiosum
Length = 282
Score = 78.6 bits (185), Expect = 2e-13
Identities = 52/198 (26%), Positives = 84/198 (42%)
Frame = +3
Query: 210 MGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGVTPANSIXXXXXXXXXXXSILTSNKVV 389
+G + L+K G V Y+ + D A G A S + +T +
Sbjct: 2 LGTGIGLRLLKTGINVIAYNRTADKTKALEDAGARIAKSPGEAAGLSDTVITCVTDADAL 61
Query: 390 LDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAPVSGGVMGAQNA 569
V G++G+ A K +L D STI+P I + G+ DAPV GG A
Sbjct: 62 EQVSFGENGIAQGAHKDLVLCDMSTINPEGAVSISKKLADAGIRMVDAPVMGGPGAAMRG 121
Query: 570 TLAFMAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMGITGMAXAECMXM 749
L MA G K +E +L + K F+ G G+ KL N+ + + ++ +E + +
Sbjct: 122 ELVIMASGDKGAYEERRGILGAVSRKMFYLGGSGTAYSIKLAMNLQIAMLAISLSEGITL 181
Query: 750 GIKMGLXPKVLLDVLNNS 803
+ P L+VLN++
Sbjct: 182 ARGASVDPHKFLEVLNST 199
>UniRef50_Q0BTJ3 Cluster: 2-hydroxy-3-oxopropionate reductase; n=1;
Granulibacter bethesdensis CGDNIH1|Rep:
2-hydroxy-3-oxopropionate reductase - Granulobacter
bethesdensis (strain ATCC BAA-1260 / CGDNIH1)
Length = 293
Score = 78.2 bits (184), Expect = 3e-13
Identities = 62/203 (30%), Positives = 93/203 (45%)
Frame = +3
Query: 186 VAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGVTPANSIXXXXXXXXXXXS 365
+A LG G MG +MA L G V ++ + AA+ G+ A S
Sbjct: 9 IAVLGTGIMGRWMACRLADAGHEVTVWNRNPVR---AAELGLPVATSAPDAAHGADVAL- 64
Query: 366 ILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAPVSG 545
++ S+ D L V A+ G++L+ SS Q ++ + DAPVSG
Sbjct: 65 LMVSDGPACDAVLETGFVDTMAQNGTVLVMSSIEPWRARAQAKKVSPRF---YVDAPVSG 121
Query: 546 GVMGAQNATLAFMAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMGITGM 725
G GA+N TLA MAGG + R P+ +G + G IG+GQ+AKL N +++G+T
Sbjct: 122 GEGGARNGTLAIMAGGEEAVLNRLAPVFAALG-RMTRIGDIGAGQLAKLANQLIVGVTIG 180
Query: 726 AXAECMXMGIKMGLXPKVLLDVL 794
A +E + G P D +
Sbjct: 181 AVSEAFVLAEAGGASPARFRDAV 203
>UniRef50_A1GFG2 Cluster: 6-phosphogluconate dehydrogenase,
NAD-binding; n=1; Salinispora arenicola CNS205|Rep:
6-phosphogluconate dehydrogenase, NAD-binding -
Salinispora arenicola CNS205
Length = 315
Score = 78.2 bits (184), Expect = 3e-13
Identities = 52/187 (27%), Positives = 80/187 (42%), Gaps = 2/187 (1%)
Frame = +3
Query: 183 NVAFLGLGNMGGFMAANLVKKG-FTVRGYDPSKDALNAAAKNGVTPANSIXXXXXXXXXX 359
++ LGLG MG M L+ G + ++ + +A + G A +
Sbjct: 2 HITMLGLGAMGSRMTRRLIATGEHDITVWNRTAEATRPLVEAGAVAAPTPAAATAQSDLV 61
Query: 360 XSILTSNKVVLDVYLGKD-GVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAP 536
S+L + V+L D G + G+L +D ST+ P +++ ++G F DAP
Sbjct: 62 ISMLRDVEAGRSVWLDPDVGALTSLAPGTLAVDCSTVTPTFSRELAACCAQRGAEFLDAP 121
Query: 537 VSGGVMGAQNATLAFMAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMGI 716
V G A TL F+AGG R P+L+ +G H G G+G KL N L +
Sbjct: 122 VLGSRPQADAGTLIFLAGGDLAVLHRIEPVLRQVGGAVHHMGPAGTGTQMKLLTNSLFAV 181
Query: 717 TGMAXAE 737
AE
Sbjct: 182 QVATVAE 188
>UniRef50_Q97ZE5 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=4;
Sulfolobaceae|Rep: 3-hydroxyisobutyrate dehydrogenase -
Sulfolobus solfataricus
Length = 289
Score = 77.8 bits (183), Expect = 4e-13
Identities = 63/216 (29%), Positives = 97/216 (44%), Gaps = 3/216 (1%)
Frame = +3
Query: 186 VAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGVTPANSIXXXXXXXXXXXS 365
+ +GLG MG +AANL K YD +++ + + K N +
Sbjct: 3 IGLIGLGIMGYRIAANLAKANKLNLVYDRTQEKIESFVKE--YKVNGVQNTKDLVESSDV 60
Query: 366 ILTSNKVVLDVYLGKDGV--VAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAPV 539
I+T ++ D Y K V + KG +LID STI P + + G DAPV
Sbjct: 61 IIT---MLADDYAVKSVVEPLIPLMKGKILIDMSTISPTLSISLAKRIESNGGTMFDAPV 117
Query: 540 SGGVMGAQNATLAFMAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMGIT 719
G + + L + GG K+ F+ + K + + G G G +KL NN+L+
Sbjct: 118 IGTSVFVEQKKLVVLVGGPKDKFDIVNDIAKETASLVVYMGPNGMGLYSKLVNNLLLASY 177
Query: 720 GMAXAECMXMGIKMGLXPKVLLDVLNN-SSXRSWST 824
A AE GI+ GL P+ ++++L SS RS +T
Sbjct: 178 VAAIAEAYNFGIRAGLEPQQVVNILTTLSSARSPTT 213
>UniRef50_Q6F842 Cluster: Putative 3-hydroxyisobutyrate
dehydrogenase or 2-hydroxy-3- oxopropionate reductase;
n=2; Acinetobacter|Rep: Putative 3-hydroxyisobutyrate
dehydrogenase or 2-hydroxy-3- oxopropionate reductase -
Acinetobacter sp. (strain ADP1)
Length = 291
Score = 77.4 bits (182), Expect = 5e-13
Identities = 51/205 (24%), Positives = 92/205 (44%)
Frame = +3
Query: 186 VAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGVTPANSIXXXXXXXXXXXS 365
+AF+G+G MG MA LV+ GF+V ++ ++ A + G +
Sbjct: 9 IAFIGMGLMGSRMATRLVQAGFSVAVWNRTQSACDVLLDMGAQALS--LEKIADYPVILM 66
Query: 366 ILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAPVSG 545
L ++ V VY + V + +++D S++ N K + A ++ + D+PVSG
Sbjct: 67 CLADDQAVNHVY---EQVHHLVRPQQIIVDFSSLSVNQTKYLADRAQQQQAIWIDSPVSG 123
Query: 546 GVMGAQNATLAFMAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMGITGM 725
G GA+ TL AGG + + + V+ + G G+GQ K+ N +++
Sbjct: 124 GTSGAEQGTLVIFAGGNESTIQDLGLIYNVLSQRVTRMGDTGTGQATKICNQLIVAANSA 183
Query: 726 AXAECMXMGIKMGLXPKVLLDVLNN 800
AE + + + G+ +L L N
Sbjct: 184 LIAEAVALAHRAGVDTTLLAPALAN 208
>UniRef50_A5P600 Cluster: 6-phosphogluconate dehydrogenase,
NAD-binding; n=1; Methylobacterium sp. 4-46|Rep:
6-phosphogluconate dehydrogenase, NAD-binding -
Methylobacterium sp. 4-46
Length = 290
Score = 77.4 bits (182), Expect = 5e-13
Identities = 60/209 (28%), Positives = 95/209 (45%), Gaps = 3/209 (1%)
Frame = +3
Query: 186 VAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGVTPANSIXXXXXXXXXXXS 365
+ ++GLG +G MA +LV G V +D +D AA G A+ +
Sbjct: 3 IGWIGLGKLGAPMARHLVAAGHAVLAFD--RDPGRLAAVPGAEAAD--LPGVAACGVVVT 58
Query: 366 ILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAPVSG 545
L + + V LG +G++A +L+++ST+ P + A G+ + APVSG
Sbjct: 59 SLPDDAALAAVALGPEGLLARMAPDGVLVETSTVSPETSAALREAAEAGGILYLAAPVSG 118
Query: 546 GVMGAQNATLAFMAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVA---KLTNNMLMGI 716
A+ ATL G + ER+ PLL A+ H +G G+ A KL N +G
Sbjct: 119 STATAEAATLTLFCSGPETALERARPLLATF-ARTIHA--VGPGEEARFLKLAINHFVGS 175
Query: 717 TGMAXAECMXMGIKMGLXPKVLLDVLNNS 803
T AE + + + G+ +L VL +S
Sbjct: 176 TAQVAAEALTLARRGGVAWDTVLAVLGSS 204
>UniRef50_A4ECY9 Cluster: Putative uncharacterized protein; n=1;
Collinsella aerofaciens ATCC 25986|Rep: Putative
uncharacterized protein - Collinsella aerofaciens ATCC
25986
Length = 359
Score = 76.6 bits (180), Expect = 8e-13
Identities = 53/195 (27%), Positives = 84/195 (43%)
Frame = +3
Query: 183 NVAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGVTPANSIXXXXXXXXXXX 362
+VAF+G G MG +A +++ G+ V + +K A + G A +
Sbjct: 6 SVAFIGTGIMGAPIAGHILDAGYPVTVNNRTKSKAAALIERGAVWAETPADAVVNADVVF 65
Query: 363 SILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAPVS 542
+++ V ++YL DG++ K G++LID +T P + + I A G D PV+
Sbjct: 66 TMVGYPSEVEELYLAGDGLLTCTKPGAVLIDLTTSSPELARDIAEAAQVSGRMAFDCPVT 125
Query: 543 GGVMGAQNATLAFMAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMGITG 722
GG GA TL + G + D +L A G GQ AKL N + +
Sbjct: 126 GGESGAIAGTLTAIVGATENDIAPVRDVLSTFAANICCFDGAGKGQAAKLANQVSLAACM 185
Query: 723 MAXAECMXMGIKMGL 767
+ A+ M GL
Sbjct: 186 VGMADAMAFAELSGL 200
>UniRef50_A1SQ87 Cluster: 6-phosphogluconate dehydrogenase,
NAD-binding; n=4; Bacteria|Rep: 6-phosphogluconate
dehydrogenase, NAD-binding - Nocardioides sp. (strain
BAA-499 / JS614)
Length = 318
Score = 76.6 bits (180), Expect = 8e-13
Identities = 52/207 (25%), Positives = 98/207 (47%), Gaps = 1/207 (0%)
Frame = +3
Query: 186 VAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGVTPANSIXXXXXXXXXXXS 365
V ++G G MG MA+ L + G V ++ ++ A ++ G A++I
Sbjct: 13 VGWIGAGRMGAAMASRLARAGEDVTVWNRTRAKAEALSEVGCGVADTIADLRGHDVVFTM 72
Query: 366 ILTSNKVVLDVYLGKDGVVAH-AKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAPVS 542
+ T + V +G+ G++A A+ ++++D ST+ + E+G+ F APVS
Sbjct: 73 VSTPADLE-QVLVGEGGLLADPARVPAVVVDCSTVSTESSAAMRAACSERGVAFLAAPVS 131
Query: 543 GGVMGAQNATLAFMAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMGITG 722
G + L+ + G +E +ER LL +G + G+ ++AK+ +N+++G+
Sbjct: 132 GNGKVVRAGGLSLVVSGPEETYERVAHLLDHLGKGATYVGEGELARLAKICHNVMLGVVT 191
Query: 723 MAXAECMXMGIKMGLXPKVLLDVLNNS 803
AE + K G+ L+ LN S
Sbjct: 192 QCLAEITVLAEKGGMSRAAFLEFLNKS 218
>UniRef50_Q4WXG9 Cluster: 3-hydroxyisobutyrate dehydrogenase,
putative; n=1; Aspergillus fumigatus|Rep:
3-hydroxyisobutyrate dehydrogenase, putative -
Aspergillus fumigatus (Sartorya fumigata)
Length = 317
Score = 76.6 bits (180), Expect = 8e-13
Identities = 54/154 (35%), Positives = 77/154 (50%), Gaps = 3/154 (1%)
Frame = +3
Query: 363 SILTSNKVVLDVYLGKD-GVVAHAKKGSLLIDSSTIDPNVPKQIFPIALE--KGLGFTDA 533
+++ + V VYL GV+ + +L+D STID + + K F DA
Sbjct: 84 TMVPEGRHVRSVYLDSHAGVLTTSVDDKILVDCSTIDTATSMDVGAAVCQNSKTAAFYDA 143
Query: 534 PVSGGVMGAQNATLAFMAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMG 713
PVSGG +GA TL FM G ++D P L+++ F CG G AKL NN G
Sbjct: 144 PVSGGSLGAVAGTLTFMVGCVEDD-----PNLELL---IFPCGGFLLGLTAKLCNNYCSG 195
Query: 714 ITGMAXAECMXMGIKMGLXPKVLLDVLNNSSXRS 815
+ +A AE M +GIK G+ P +L V S+ +S
Sbjct: 196 LIAIATAEAMNIGIKSGMKPSLLARVFATSTAQS 229
>UniRef50_Q4Q9Z1 Cluster: Dehydrogenase-like protein; n=6;
Trypanosomatidae|Rep: Dehydrogenase-like protein -
Leishmania major
Length = 431
Score = 76.2 bits (179), Expect = 1e-12
Identities = 60/223 (26%), Positives = 100/223 (44%), Gaps = 16/223 (7%)
Frame = +3
Query: 183 NVAFLGLGNMGGFMAANLVKKGFTV-------RGYDPSKDALNAAAKNGVTPANSIXXXX 341
NV +G+GNMG + NL K + R ++ + + +G T A I
Sbjct: 9 NVGVVGMGNMGIPITRNLAFKARSAMYLQIHSRTLSKARQVCDDMSADGATCAMRIHDRY 68
Query: 342 XXXXXXXSIL--------TSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFP 497
++ S KV+L+ + +V +A+ G +++D +T+D + ++
Sbjct: 69 STMTKWCDVILLTLAHRAASRKVLLE---DSEALVTNARPGQIIVDHTTVDMELSRECAH 125
Query: 498 IALEKGLGFTDAPVSGGVMGAQNATLAFMAGGRKEDFERSLPLLKVMGAKQFHCGQIGSG 677
A +G F DAP+SG A N L M GG E +R P+ ++ H G GSG
Sbjct: 126 EAERRGAVFLDAPMSGSPKQAFNNQLVLMVGGPAEQVQRVSPIFRMYADHIHHMGANGSG 185
Query: 678 QVAKLTNNMLMGITGMAXAECMXMGIKMGLXP-KVLLDVLNNS 803
AKL + L+ A AE M + ++G+ + L+ VL+ S
Sbjct: 186 TAAKLLSQALVASHNAAAAEAMTIANRLGIEDYQKLIQVLDAS 228
>UniRef50_Q6RXW5 Cluster: Succinic semialdehyde dehydrogenase; n=2;
Rhodococcus|Rep: Succinic semialdehyde dehydrogenase -
Rhodococcus sp. TK6
Length = 262
Score = 75.4 bits (177), Expect = 2e-12
Identities = 57/209 (27%), Positives = 99/209 (47%), Gaps = 1/209 (0%)
Frame = +3
Query: 195 LGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGVTPANSIXXXXXXXXXXXSILT 374
+GLG +GG + A+L + G V GYD +++ L ++ +PA S S+
Sbjct: 5 IGLGPIGGKIGAHLAELGRKVYGYDFNQERLREWSEETASPAGS-DLAAVDWPSIDSVHV 63
Query: 375 SNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAPVSGGVM 554
+ ++ V + + AH + + +T+ P ++I P A G +APVSGG
Sbjct: 64 AVRLADQVSSVFEALAAHTAQPLTVFVHTTLAPADARKILPSA-PAGWRVFEAPVSGGPQ 122
Query: 555 GAQNATL-AFMAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMGITGMAX 731
GA++ ++ F+AG D E + LL+ + + F G + KL NN L A
Sbjct: 123 GARHGSMTVFLAGPAPTDAENA--LLEDISGRVFQMESYGQPALVKLLNNALATYNLAAT 180
Query: 732 AECMXMGIKMGLXPKVLLDVLNNSSXRSW 818
A + + + G+ K L +V+ S+ +SW
Sbjct: 181 ARMLNLAAEHGVPAKDLFEVIGVSTGQSW 209
>UniRef50_Q21ZN3 Cluster: 6-phosphogluconate dehydrogenase,
NAD-binding; n=1; Rhodoferax ferrireducens T118|Rep:
6-phosphogluconate dehydrogenase, NAD-binding -
Rhodoferax ferrireducens (strain DSM 15236 / ATCC
BAA-621 / T118)
Length = 292
Score = 75.4 bits (177), Expect = 2e-12
Identities = 54/212 (25%), Positives = 92/212 (43%), Gaps = 2/212 (0%)
Frame = +3
Query: 168 SNTDKNVAFLGLGNMGGFMAANLVKKGF--TVRGYDPSKDALNAAAKNGVTPANSIXXXX 341
SNT + +GLG MG + NL+K GF TV G + ++ +++ G + S+
Sbjct: 3 SNTSLRIGLIGLGLMGHGIGRNLLKNGFALTVMG-NVNRAPVDSLVSLGANESKSVAELV 61
Query: 342 XXXXXXXSILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLG 521
+T + V + G++ + G ++ID ST P+ I LE G
Sbjct: 62 DASDVVMLCVTGSPQVESLMNRDQGILQSIRPGQIVIDCSTSQPSSSAIINAALLEAGAL 121
Query: 522 FTDAPVSGGVMGAQNATLAFMAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNN 701
F DAP+ A+ L M G + E P+L+ H G++ S Q KL NN
Sbjct: 122 FVDAPLGRTPAEAEAGKLNVMVGATPQLLEHIRPVLQAFCENIIHVGEVISAQKLKLINN 181
Query: 702 MLMGITGMAXAECMXMGIKMGLXPKVLLDVLN 797
+ T E + ++G+ + + D+++
Sbjct: 182 FAVVGTAALLTEALRACDQVGVSRQAMYDLMS 213
>UniRef50_A3Q3U7 Cluster: 6-phosphogluconate dehydrogenase,
NAD-binding; n=3; Mycobacterium|Rep: 6-phosphogluconate
dehydrogenase, NAD-binding - Mycobacterium sp. (strain
JLS)
Length = 279
Score = 74.9 bits (176), Expect = 2e-12
Identities = 58/210 (27%), Positives = 82/210 (39%)
Frame = +3
Query: 186 VAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGVTPANSIXXXXXXXXXXXS 365
V FLG G +G M L+ G V Y +DA G A+S+ S
Sbjct: 5 VGFLGAGQLGEPMVERLLGAGHDVLVYARREDARRRLEAKGAALADSVADLAHGSDVLIS 64
Query: 366 ILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAPVSG 545
L S+ + + LG +G +A+AK ++ + S T G DAPVSG
Sbjct: 65 CLFSDAQLRETGLGPNGFIANAKPAAVFV-SHTTGTVATLTALRDHSSSGPVVLDAPVSG 123
Query: 546 GVMGAQNATLAFMAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMGITGM 725
TL + GG + P+L G +GS KL NN+L
Sbjct: 124 TADDIAAGTLTVLLGGPADAVAAVTPVLAAYADPLVPTGTLGSALALKLINNLLFAANAQ 183
Query: 726 AXAECMXMGIKMGLXPKVLLDVLNNSSXRS 815
A +G ++G+ P+VLL L S S
Sbjct: 184 LLAAATELGTQLGVDPEVLLSTLQVCSAGS 213
>UniRef50_UPI0000E49FD0 Cluster: PREDICTED: similar to gamma
hydroxybutyrate dehydrogenase; n=3; Strongylocentrotus
purpuratus|Rep: PREDICTED: similar to gamma
hydroxybutyrate dehydrogenase - Strongylocentrotus
purpuratus
Length = 219
Score = 74.5 bits (175), Expect = 3e-12
Identities = 43/137 (31%), Positives = 64/137 (46%)
Frame = +3
Query: 396 VYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAPVSGGVMGAQNATL 575
+ G++GV+ +G +D ST+D + + F +APV G V A +L
Sbjct: 6 IVFGENGVLEGITEGKAFVDMSTVDIGTVTGVSEAVQARDGRFMEAPVCGSVQPAMEGSL 65
Query: 576 AFMAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMGITGMAXAECMXMGI 755
+A G KE ++ + MG K F+ G+ KL NM++G AE M +
Sbjct: 66 IIIAAGDKELYDECESCFQAMGKKAFYLSDTGNAARMKLVINMIIGGVMCCFAEGMALAD 125
Query: 756 KMGLXPKVLLDVLNNSS 806
K GL VLLD+LN S
Sbjct: 126 KSGLSQSVLLDILNLGS 142
>UniRef50_Q120Q9 Cluster: 6-phosphogluconate dehydrogenase,
NAD-binding; n=7; Burkholderiales|Rep:
6-phosphogluconate dehydrogenase, NAD-binding -
Polaromonas sp. (strain JS666 / ATCC BAA-500)
Length = 297
Score = 74.5 bits (175), Expect = 3e-12
Identities = 54/206 (26%), Positives = 87/206 (42%), Gaps = 1/206 (0%)
Frame = +3
Query: 180 KNVAFLGLGNMGGFMAANLVKKGFTVRGYD-PSKDALNAAAKNGVTPANSIXXXXXXXXX 356
K + +G+G MG +A+N++K G+ + + P L G T +S
Sbjct: 2 KKIGMVGIGMMGHGIASNIIKHGYPMVLLEHPGNQPLQGLIAAGATTTDSAATLAGVVDI 61
Query: 357 XXSILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAP 536
+T V DV K G++ K G+++ID ST P+ +I + G F DAP
Sbjct: 62 IILCVTGTPEVEDVLYRKGGLLEGIKPGTIVIDCSTAIPSSTIRIAESVEKAGGRFLDAP 121
Query: 537 VSGGVMGAQNATLAFMAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMGI 716
++ A L + GG FE P+L+ G +GSG KL +N +
Sbjct: 122 MTRTPKEAAEGRLNLIVGGDPALFESCKPVLECYAENIVLAGPVGSGHRLKLLHNFVSLG 181
Query: 717 TGMAXAECMXMGIKMGLXPKVLLDVL 794
AE G+ P+V +++L
Sbjct: 182 FSAVLAEAAACADCSGIDPQVFVEIL 207
>UniRef50_Q0RIL5 Cluster: Putative uncharacterized protein; n=1;
Frankia alni ACN14a|Rep: Putative uncharacterized
protein - Frankia alni (strain ACN14a)
Length = 493
Score = 74.5 bits (175), Expect = 3e-12
Identities = 50/203 (24%), Positives = 97/203 (47%)
Frame = +3
Query: 195 LGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGVTPANSIXXXXXXXXXXXSILT 374
+GLG +GG +A ++ ++G +D DA A G + +++T
Sbjct: 13 VGLGMIGGGVAVSMARRGRVPAVHDVRPDASAALPGVGDPLGSPAEVARSSDVVMVAVVT 72
Query: 375 SNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAPVSGGVM 554
+++ DV G++G++A A G ++ ST++ V ++ + E +GF D V+ G
Sbjct: 73 ADQA-RDVIGGENGLLAGAHPGLTIVLLSTVELAVVHELAALCAEHDVGFLDCGVTPGDR 131
Query: 555 GAQNATLAFMAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMGITGMAXA 734
A + +A + GG + E + P+L + HCG +G+G V K+ N++ + A
Sbjct: 132 AADHGMVAIV-GGDEATVEAARPVLDDWARRVVHCGPLGAGMVTKIARNVVTYGSWRAVF 190
Query: 735 ECMXMGIKMGLXPKVLLDVLNNS 803
E + G+ P L +V++ +
Sbjct: 191 EASALARAAGVNPARLAEVIDTA 213
>UniRef50_A0GI22 Cluster: 6-phosphogluconate dehydrogenase,
NAD-binding; n=1; Burkholderia phytofirmans PsJN|Rep:
6-phosphogluconate dehydrogenase, NAD-binding -
Burkholderia phytofirmans PsJN
Length = 355
Score = 74.5 bits (175), Expect = 3e-12
Identities = 40/93 (43%), Positives = 52/93 (55%)
Frame = +3
Query: 516 LGFTDAPVSGGVMGAQNATLAFMAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLT 695
+G+ DAPVSGGV GA TLA MAGG D E PLL ++ H G +G+GQ AKL
Sbjct: 175 IGWIDAPVSGGVAGATAGTLAVMAGGAAADVEAVKPLLGAYASRVTHMGDVGAGQTAKLC 234
Query: 696 NNMLMGITGMAXAECMXMGIKMGLXPKVLLDVL 794
N ++ T A AE + + + GL L + L
Sbjct: 235 NQTIVTATLAAIAEAVSLAQRSGLDASRLTEGL 267
>UniRef50_A0AWL7 Cluster: 6-phosphogluconate dehydrogenase,
NAD-binding precursor; n=1; Arthrobacter sp. FB24|Rep:
6-phosphogluconate dehydrogenase, NAD-binding precursor
- Arthrobacter sp. (strain FB24)
Length = 297
Score = 74.5 bits (175), Expect = 3e-12
Identities = 58/211 (27%), Positives = 97/211 (45%), Gaps = 3/211 (1%)
Frame = +3
Query: 183 NVAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGVTPANSIXXXXXXXXXXX 362
+V +GLG MG +AA+L+ +V +D D + A G P+ S
Sbjct: 5 HVGVVGLGGMGKALAASLIAADHSVAVWDRHTDRVATTAMIGAAPSVSPRQLAEQSHVIF 64
Query: 363 SILTSNKVVLDVYLGKD-GVVAHAKKGSLLIDSSTIDPNVPKQIFP--IALEKGLGFTDA 533
L + V +V ++ GV+A + G+L++D +T DP + + + AL G + DA
Sbjct: 65 LALPNPTAVREVLYDEEAGVLAGLRAGALIVDMTTGDPELAQDVAQRVAALGNGARYVDA 124
Query: 534 PVSGGVMGAQNATLAFMAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMG 713
PVSG A N T+ M GG + +++ + + G +G G KL + +
Sbjct: 125 PVSGT---APNLTV--MIGGEAGVLGGAESIVQDVAGTLLYAGALGDGFATKLVHQHVKY 179
Query: 714 ITGMAXAECMXMGIKMGLXPKVLLDVLNNSS 806
T +A AE + + + GL ++D L SS
Sbjct: 180 ATHLAVAEALVIAQQAGLDVAKVIDALERSS 210
>UniRef50_Q392H4 Cluster: 6-phosphogluconate dehydrogenase,
NAD-binding; n=8; Bacteria|Rep: 6-phosphogluconate
dehydrogenase, NAD-binding - Burkholderia sp. (strain
383) (Burkholderia cepacia (strain ATCC 17760/ NCIB 9086
/ R18194))
Length = 292
Score = 74.1 bits (174), Expect = 4e-12
Identities = 56/207 (27%), Positives = 91/207 (43%), Gaps = 3/207 (1%)
Frame = +3
Query: 186 VAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGVTPANSIXXXXXXXXXXXS 365
VA LG+G MG +A NL ++GFTVR ++ ++ +A A +GV + +
Sbjct: 12 VAVLGIGVMGAPIARNLARQGFTVRAWNRTRAKADALAADGVAAFATPAETVSDARVVVT 71
Query: 366 ILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAPVSG 545
+L VL + G++ + ST+ ++ A L F DAPV G
Sbjct: 72 VLNDADGVLK---AMEAAAPKLAAGTIWVQVSTVGVRGIARLAAFARTHDLVFYDAPVQG 128
Query: 546 GVMGAQNATLAFMAGGRKEDFERSLPLLKVMGAKQFHC---GQIGSGQVAKLTNNMLMGI 716
A+NA L +A G + D + PL +G + G G+G KL N
Sbjct: 129 SRQPAENAQLVVLAAGPESDRAQVQPLFDAIGRRTLWVADDGSTGAGSRLKLALNHYAFT 188
Query: 717 TGMAXAECMXMGIKMGLXPKVLLDVLN 797
A AE + + +G P+ ++DV++
Sbjct: 189 LTHAIAESLKLAGALGADPRDVIDVVS 215
>UniRef50_Q221W9 Cluster: 2-hydroxy-3-oxopropionate reductase; n=1;
Rhodoferax ferrireducens T118|Rep:
2-hydroxy-3-oxopropionate reductase - Rhodoferax
ferrireducens (strain DSM 15236 / ATCC BAA-621 / T118)
Length = 303
Score = 74.1 bits (174), Expect = 4e-12
Identities = 54/219 (24%), Positives = 89/219 (40%), Gaps = 3/219 (1%)
Frame = +3
Query: 168 SNTDKNVAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAK---NGVTPANSIXXX 338
S + V F+G+G MG MA +++ KG V K A +G P +
Sbjct: 5 STSSLKVGFIGVGMMGCGMAKHVLAKGHPVALLIRKKADEERCADLLTHGAQPLKTAAEV 64
Query: 339 XXXXXXXXSILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGL 518
+T + V +V G G++ K G +++D ST P+ +++ KG
Sbjct: 65 AATADVIIICVTGSPQVEEVVFGDTGILQTLKPGCVVVDCSTSLPDSTRRVAQAIAAKGG 124
Query: 519 GFTDAPVSGGVMGAQNATLAFMAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTN 698
F DA ++G A L + GG E P+ + F+CG + +G KL +
Sbjct: 125 QFLDAAMTGTPKHADEGKLNLLVGGDPEVLTSVRPVFALFAENIFYCGAVSAGHTTKLLH 184
Query: 699 NMLMGITGMAXAECMXMGIKMGLXPKVLLDVLNNSSXRS 815
++ AE K G+ +VL DV+ + S
Sbjct: 185 QFVVLGNAAILAEAFSCASKTGVNLEVLCDVIASGGANS 223
>UniRef50_Q7NEW9 Cluster: Glr3759 protein; n=3; Bacteria|Rep:
Glr3759 protein - Gloeobacter violaceus
Length = 290
Score = 73.7 bits (173), Expect = 6e-12
Identities = 53/207 (25%), Positives = 92/207 (44%), Gaps = 1/207 (0%)
Frame = +3
Query: 189 AFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGVTPANSIXXXXXXXXXXXSI 368
A LG+G MG MAA L+K G V ++ + A+ G A + +
Sbjct: 5 AVLGMGAMGSRMAAALLKAGHQVTVWNRNSQKTAPLAEMGAKAAQTPRAAVEEVDFAVCM 64
Query: 369 LTSNKVVLDVYLG-KDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAPVSG 545
+ + V+L + G +A ++ I+SST+ +++ +G DAPVSG
Sbjct: 65 VRDDAASRFVWLDFETGALAGLPADAVAIESSTLSVAGVQELAEHFQARGKTLLDAPVSG 124
Query: 546 GVMGAQNATLAFMAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMGITGM 725
A+ L F+ GG ++ P+L MG H G +G+G KL N L+G+
Sbjct: 125 SRPQAEAGQLIFLVGGDAGAVAKAGPILNAMGGTVHHAGPLGNGAAVKLAINALLGVQVA 184
Query: 726 AXAECMXMGIKMGLXPKVLLDVLNNSS 806
A E + + G+ ++++ ++S
Sbjct: 185 AMGELIALLRHCGIDEVRAVEIIGSTS 211
>UniRef50_A3ES45 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=1;
Leptospirillum sp. Group II UBA|Rep:
3-hydroxyisobutyrate dehydrogenase - Leptospirillum sp.
Group II UBA
Length = 307
Score = 73.7 bits (173), Expect = 6e-12
Identities = 53/214 (24%), Positives = 96/214 (44%), Gaps = 2/214 (0%)
Frame = +3
Query: 180 KNVAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGVTPANSIXXXXXXXXXX 359
K ++G GNMG MA NL++ G + ++ + L K G +
Sbjct: 12 KEAVWIGTGNMGLPMAKNLLRSGIRLGVHNRTPQRLAPLLKAGAHAIADLRGSLSGTPLV 71
Query: 360 XSILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAPV 539
++L + V + L + G++ +G + + T+ P ++ E+G APV
Sbjct: 72 FTMLADDAAVKETVLKEGGLLDSLPQGGVHVSMGTLSPGFVLELSKTHTERGQILVSAPV 131
Query: 540 SGGVMGAQNATLAFMAGGRKEDFERSLPLLKVMGAKQFHCGQIGS--GQVAKLTNNMLMG 713
G A+ TL +A G ++ E LPLL+ +G+ F G+ S + L N L G
Sbjct: 132 FGRPDRAEAGTLTIVAAGPQKTLESLLPLLEHLGSPVFCVGEDPSLANHIKVLGNFTLAG 191
Query: 714 ITGMAXAECMXMGIKMGLXPKVLLDVLNNSSXRS 815
+ AE + + ++G+ P L+++L+ + RS
Sbjct: 192 LL-ETLAESLSLARRVGVSPGQLVEILDTALYRS 224
>UniRef50_Q9I1R8 Cluster: Probable dehydrogenase; n=7; Pseudomonas
aeruginosa|Rep: Probable dehydrogenase - Pseudomonas
aeruginosa
Length = 291
Score = 73.3 bits (172), Expect = 8e-12
Identities = 53/207 (25%), Positives = 96/207 (46%), Gaps = 1/207 (0%)
Frame = +3
Query: 186 VAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGVTPANSIXXXXXXXXXXXS 365
V FLGLG MG MA LV+ G V ++ S A G A + S
Sbjct: 3 VGFLGLGGMGAAMATRLVQAGLEVTVWNRSAAACEPLVALGAARAEEVGELFGLDVVI-S 61
Query: 366 ILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAPVSG 545
+L ++ + V L G + A+ G + + ST+ + + + +GL F APV G
Sbjct: 62 MLADDQAIRGVLLDS-GALERARPGLIHLSMSTLSLDCVEALDQAHQRQGLAFVAAPVFG 120
Query: 546 GVMGAQNATLAFMAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVA-KLTNNMLMGITG 722
A+ L + GG +E E+ LL++MG K + G+ G +A K++ N ++
Sbjct: 121 RTDVAEAGKLNIVVGGPEEAIEQVKALLEIMGQKTWFFGKDPRGAMAVKISGNFMIASAI 180
Query: 723 MAXAECMXMGIKMGLXPKVLLDVLNNS 803
+ E + + ++G+ P +++++++
Sbjct: 181 ESMGESVALVKRLGVEPGRFMELMSST 207
>UniRef50_Q21ZT0 Cluster: 6-phosphogluconate dehydrogenase,
NAD-binding; n=1; Rhodoferax ferrireducens T118|Rep:
6-phosphogluconate dehydrogenase, NAD-binding -
Rhodoferax ferrireducens (strain DSM 15236 / ATCC
BAA-621 / T118)
Length = 315
Score = 73.3 bits (172), Expect = 8e-12
Identities = 60/236 (25%), Positives = 102/236 (43%), Gaps = 2/236 (0%)
Frame = +3
Query: 180 KNVAFLGLGNMGGFMAANLVKKGFTVRGYD-PSKDALNAAAKNGV-TPANSIXXXXXXXX 353
+ + F+G+G MG +A NL+K+G + D P ++ K G T A
Sbjct: 5 RKLGFIGVGLMGHGLAKNLLKQGHAMTLLDHPGNQPIDDLMKMGAQTVATPKEVATAADV 64
Query: 354 XXXSILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDA 533
+ S +V VY G DG++ + G +++D++T DP ++ +G + DA
Sbjct: 65 VFLCVNGSPQVEACVY-GADGLLEGLRAGGVVVDATTADPVSTLKVAAAVQARGGRYVDA 123
Query: 534 PVSGGVMGAQNATLAFMAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMG 713
P++ A++ + M GG PL++ F G++GSG KL +N +
Sbjct: 124 PMTRTSQHAEDGCVNAMLGGDAVTIAEVRPLIEAYAENIFIGGEVGSGHRLKLLHNYISL 183
Query: 714 ITGMAXAECMXMGIKMGLXPKVLLDVLNNSSXRSWSTXXVLSXPRTGAHRSVQYKL 881
T AE K G+ KVL +VL S ++ +G S+ + L
Sbjct: 184 GTLALLAEAYTCAGKAGVDRKVLTEVLATGGGDSVVLKRLMPFLDSGEPGSMMFSL 239
>UniRef50_Q033P2 Cluster: 3-hydroxyisobutyrate dehydrogenase related
beta-hydroxyacid dehydrogenase; n=1; Lactobacillus casei
ATCC 334|Rep: 3-hydroxyisobutyrate dehydrogenase related
beta-hydroxyacid dehydrogenase - Lactobacillus casei
(strain ATCC 334)
Length = 285
Score = 73.3 bits (172), Expect = 8e-12
Identities = 56/206 (27%), Positives = 94/206 (45%), Gaps = 3/206 (1%)
Frame = +3
Query: 186 VAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGVTPANSIXXXXXXXXXXXS 365
+ F+G+G+MG M +L K G+ V +D + A A + V A S+ +
Sbjct: 3 ITFIGVGDMGSHMVPHLAKAGYDVTVWDKVPAKMAAVAGDHVRTATSLEDAVTASRVIIT 62
Query: 366 ILTSNKVVLDVYLGKD---GVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAP 536
+ S+ V +++G G+V + + GS LI +ST+DP I + K D P
Sbjct: 63 SVMSDDVPA-LHIGTTETPGIVHYLQPGSTLIVTSTLDPRKITAIQAVMPTK-THLLDVP 120
Query: 537 VSGGVMGAQNATLAFMAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMGI 716
+ GGV A+ A L +A G K+ P+LK G ++ G+ G+G KL N+ +
Sbjct: 121 MIGGVKYAREAGLVLIAAGDKQAVADVTPILKTFGTVKY-VGEQGNGAKLKLITNVAIMA 179
Query: 717 TGMAXAECMXMGIKMGLXPKVLLDVL 794
E + + + + LD+L
Sbjct: 180 AEAGIRETLDLADAYDIDYQTTLDLL 205
>UniRef50_A6R0U9 Cluster: Predicted protein; n=1; Ajellomyces
capsulatus NAm1|Rep: Predicted protein - Ajellomyces
capsulatus NAm1
Length = 444
Score = 72.9 bits (171), Expect = 1e-11
Identities = 61/207 (29%), Positives = 93/207 (44%), Gaps = 9/207 (4%)
Frame = +3
Query: 174 TDK-NVAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGVTPANSI-XXXXXX 347
T+K ++ F+GLG MG MA NL+K G+ V+GYD + + G A+S
Sbjct: 3 TEKPSIGFVGLGLMGFGMATNLIKLGYVVKGYDIQETTMARFKDAGGQIASSPGGAAGGN 62
Query: 348 XXXXXSILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTID----PNVPKQIFPIALEKG 515
+ T+ + + ++ ++G+ G+ LI ST+ + Q+ I E
Sbjct: 63 MFCVCMVATAAQAQVAIFDHENGIAKGLPSGATLILCSTVSAVSAQSYRDQLVSIGRE-D 121
Query: 516 LGFTDAPVSGGVMGAQNATLAFMAGGRKEDFERSLPLLKVMGAKQ---FHCGQIGSGQVA 686
+ F DAPVSGG A TL MAGG E LL M F G +G+G
Sbjct: 122 VYFIDAPVSGGARKAGEGTLTIMAGGSDAALEEGKFLLTEMADTNKLYFVPGGVGAGSNM 181
Query: 687 KLTNNMLMGITGMAXAECMXMGIKMGL 767
K+ + + I +A +E M +GL
Sbjct: 182 KMIHQVFAAIHILAASEVMGFAAHLGL 208
>UniRef50_Q2JEN4 Cluster: 6-phosphogluconate dehydrogenase,
NAD-binding; n=1; Frankia sp. CcI3|Rep:
6-phosphogluconate dehydrogenase, NAD-binding - Frankia
sp. (strain CcI3)
Length = 290
Score = 72.5 bits (170), Expect = 1e-11
Identities = 55/207 (26%), Positives = 89/207 (42%), Gaps = 1/207 (0%)
Frame = +3
Query: 186 VAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGVTPANSIXXXXXXXXXXXS 365
+ F+GLG MG MA NL+ G TV ++ S D + A G PA+ S
Sbjct: 3 IGFIGLGGMGSAMARNLIDAGHTVLAWNRSPDPVTELAAAGAVPAS--ISEAFATGIVLS 60
Query: 366 ILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAPVSG 545
+L ++ V D L V+ A G+L ++ +T+ + Q E GL + APV G
Sbjct: 61 MLADDQAVTDRLL-DPRVLTAAPAGALHVNMATVSTALAIQARREHAEHGLRYLAAPVFG 119
Query: 546 GVMGAQNATLAFMAGGRKEDFERSLPLLKVMGAKQFHCGQIGS-GQVAKLTNNMLMGITG 722
A+ L + G + PL V+G + + G + K+ N L+ +
Sbjct: 120 RTDAARAGNLTIVTSGDPDTIAEVQPLFDVLGRRTWTVGDAPEHANLVKILGNYLIACSI 179
Query: 723 MAXAECMXMGIKMGLXPKVLLDVLNNS 803
A AE + G+ P ++VL ++
Sbjct: 180 EAMAEASAVIEAGGMNPATFIEVLTDN 206
>UniRef50_Q39KK8 Cluster: 6-phosphogluconate dehydrogenase,
NAD-binding; n=34; Bacteria|Rep: 6-phosphogluconate
dehydrogenase, NAD-binding - Burkholderia sp. (strain
383) (Burkholderia cepacia (strain ATCC 17760/ NCIB 9086
/ R18194))
Length = 289
Score = 72.1 bits (169), Expect = 2e-11
Identities = 53/208 (25%), Positives = 92/208 (44%), Gaps = 1/208 (0%)
Frame = +3
Query: 183 NVAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGVTPANSIXXXXXXXXXXX 362
++ F+GLG MG +A NL+K G TVR ++ S++ A G ++
Sbjct: 2 DLGFIGLGEMGQAIATNLLKAGHTVRVWNRSRERAEPLAAIGAQIVDT-PADAFRGDAVF 60
Query: 363 SILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAPVS 542
S+L + ++ D ++A A +G + ++ +T+ + + + +G+ + APV
Sbjct: 61 SMLADDAAARAIF--DDALLAQAPRGLIHVNMATVSVALAESLAHAHASRGIHYVAAPVM 118
Query: 543 GGVMGAQNATLAFMAGGRKEDFERSLPLLKVMGAKQFHCGQIGS-GQVAKLTNNMLMGIT 719
G A A L MAGG E +R PL +G K + G + VAK+ N +
Sbjct: 119 GRPDVAAAARLTIMAGGPAEAIDRVQPLFDAIGQKTWRFGSLPQHANVAKIAANFTLASA 178
Query: 720 GMAXAECMXMGIKMGLXPKVLLDVLNNS 803
E + G+ + LDV+ S
Sbjct: 179 IETLGEASALLGAHGVAMRDFLDVITGS 206
>UniRef50_A3H9B3 Cluster: 6-phosphogluconate dehydrogenase,
NAD-binding; n=1; Caldivirga maquilingensis IC-167|Rep:
6-phosphogluconate dehydrogenase, NAD-binding -
Caldivirga maquilingensis IC-167
Length = 293
Score = 72.1 bits (169), Expect = 2e-11
Identities = 43/141 (30%), Positives = 68/141 (48%)
Frame = +3
Query: 186 VAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGVTPANSIXXXXXXXXXXXS 365
V +GLG MGG L+ KGF + YD +D +N K G T A+S +
Sbjct: 3 VGLVGLGRMGGAFGRVLLSKGFNLVVYDVVRDKVNEFVKLGATGASSPADLASRVDIVLT 62
Query: 366 ILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAPVSG 545
+ ++ VLDVYLG +G+++ AK G + +++ST D ++ + +GF A +
Sbjct: 63 NVPRSEDVLDVYLGGNGILSGAKPGLIAVETSTTDIKTKLRVAEECRRRNVGFIVAMLGK 122
Query: 546 GVMGAQNATLAFMAGGRKEDF 608
V A+ GG +E F
Sbjct: 123 TVPQAERGETPLFVGGPEEVF 143
>UniRef50_A3ET09 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=3;
Bacteria|Rep: 3-hydroxyisobutyrate dehydrogenase -
Leptospirillum sp. Group II UBA
Length = 311
Score = 71.7 bits (168), Expect = 2e-11
Identities = 48/209 (22%), Positives = 95/209 (45%), Gaps = 2/209 (0%)
Frame = +3
Query: 195 LGLGNMGGFMAANLVKKGFTVRG-YDPSKDALNAAA-KNGVTPANSIXXXXXXXXXXXSI 368
+G+G MG MA L G+ V YD +A A + G + A ++ ++
Sbjct: 14 VGVGRMGSNMALRLNDVGYRVASVYDVRLEAARRVADETGASVARTLAEVTAQSDVIITV 73
Query: 369 LTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAPVSGG 548
+ +++ + ++ + G + ++ +T+ P++ ++ + ++G +A ++
Sbjct: 74 VGTDREMDALFAETGDSLLVGASGRVFVNCATLSPDIHVEVERRSNDRGADCLEASMASS 133
Query: 549 VMGAQNATLAFMAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMGITGMA 728
+ A+ TL M GG+KE FER P+L+ M A G G K NM+M I
Sbjct: 134 ITQAREGTLYLMVGGKKEAFERVRPVLEAMSASLRWIGPAGQAAKIKALVNMVMNINTAG 193
Query: 729 XAECMXMGIKMGLXPKVLLDVLNNSSXRS 815
AE + + +GL ++ +V + + S
Sbjct: 194 LAEGLGLADALGLDLAMVREVFSQTGAAS 222
>UniRef50_Q8U2W2 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=17;
Pyrococcus|Rep: 3-hydroxyisobutyrate dehydrogenase -
Pyrococcus furiosus
Length = 278
Score = 71.7 bits (168), Expect = 2e-11
Identities = 36/127 (28%), Positives = 65/127 (51%)
Frame = +3
Query: 435 KGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAPVSGGVMGAQNATLAFMAGGRKEDFER 614
+G +++D++T + I G + ++PV G V+ A+N L + G +E FER
Sbjct: 77 RGKIIVDTTTNHHEKVLEFHEIYRNVGAFYLESPVIGSVIPARNGQLTILVSGEREAFER 136
Query: 615 SLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMGITGMAXAECMXMGIKMGLXPKVLLDVL 794
P L+ +G + F+ + G KL NN ++G A E + +G K GL + ++++L
Sbjct: 137 VRPYLQKLGKRIFYFNEPGKATKLKLINNFVLGAFMAALGEAIALGEKAGLSREEIIEIL 196
Query: 795 NNSSXRS 815
N + S
Sbjct: 197 ENGAGNS 203
>UniRef50_Q21AH6 Cluster: 6-phosphogluconate dehydrogenase,
NAD-binding; n=3; Bacteria|Rep: 6-phosphogluconate
dehydrogenase, NAD-binding - Rhodopseudomonas palustris
(strain BisB18)
Length = 292
Score = 70.5 bits (165), Expect = 5e-11
Identities = 57/221 (25%), Positives = 94/221 (42%), Gaps = 2/221 (0%)
Frame = +3
Query: 168 SNTDKNVAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGVTPANSIXXXXXX 347
S + N+ +GLG MGG +A L +++ YD SK A+ +G + A S
Sbjct: 2 SRSIDNIGIIGLGAMGGAVATRLTSGPWSLAVYDLSKAAIERLVSHGASAAASARDAVAG 61
Query: 348 XXXXXSILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLG-F 524
S L + V + A +G++ +D STIDP +++ + + G F
Sbjct: 62 RAVVFSCLPTPDHVEAFWTEH---AADLAEGAIAVDLSTIDPATSRRVSDMIAKGGRARF 118
Query: 525 TDAPVSGGVMGAQNATLAFMAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNM 704
+ A+ + GG + E P+ K M + F G + + KL +N
Sbjct: 119 VACTMGKTPAMAEKGEIPLFVGGDQVSLEALAPVFKHMSSVVFDMGSVEGATMFKLISN- 177
Query: 705 LMGITGMA-XAECMXMGIKMGLXPKVLLDVLNNSSXRSWST 824
L+G+T +A AE + K G+ P+V L + WST
Sbjct: 178 LVGMTNLAILAEGYLLARKAGIDPEVFSSALKTTG--GWST 216
>UniRef50_Q55W03 Cluster: Putative uncharacterized protein; n=2;
Filobasidiella neoformans|Rep: Putative uncharacterized
protein - Cryptococcus neoformans (Filobasidiella
neoformans)
Length = 414
Score = 70.5 bits (165), Expect = 5e-11
Identities = 46/150 (30%), Positives = 76/150 (50%), Gaps = 9/150 (6%)
Frame = +3
Query: 441 SLLIDSSTIDPNVPKQIFPI---ALEKGLGFTDAPVSGGVMGAQNATLAFMAGGRKEDFE 611
++L+D +T+DP V I + + + DAPVSGG + A+ L M G
Sbjct: 170 TMLVDQTTLDPTVSLSISSLIHDSTSRAALMIDAPVSGGTVAAERGELTIMFGSPAPIAT 229
Query: 612 R-SLPLLKVMGAKQ--FHCGQIGSGQVAKLTNNMLMGITGMAXAECMXMGIKMGLXPKVL 782
R ++PLL++M + CG G+G K+ NN+++ +A +E + +G + + +L
Sbjct: 230 RLAMPLLQMMAREGGVIECGGSGTGVGVKVCNNLVLASNQIALSEGLALGRSLNIDIALL 289
Query: 783 LDVLNNSSXRSWST---XXVLSXPRTGAHR 863
V+N SS SWS+ + S P T A R
Sbjct: 290 QSVINTSSGSSWSSRVNPPISSIPGTPASR 319
>UniRef50_Q3W031 Cluster: Putative dehydrogenase; n=1; Frankia sp.
EAN1pec|Rep: Putative dehydrogenase - Frankia sp.
EAN1pec
Length = 285
Score = 69.7 bits (163), Expect = 9e-11
Identities = 53/205 (25%), Positives = 87/205 (42%), Gaps = 2/205 (0%)
Frame = +3
Query: 186 VAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGVTPANSIXXXXXXXXXXXS 365
VAFLGLG MG MA +++ G + ++ + G + A
Sbjct: 3 VAFLGLGRMGVRMAHHILAAGHELAVWNRTPGRAGELTARGASEAADPAGAVRGADACVL 62
Query: 366 ILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAPVSG 545
+L DV V+ A G L+I+ +T+ P ++ +AL GL + DAPV G
Sbjct: 63 MLFDPASAADVLA---AVIPAAPPGLLVINCTTVGPAAAREQGSVALAAGLRYLDAPVIG 119
Query: 546 GVMGAQNATLAFMAGGRKEDFERSLPLLKVMG--AKQFHCGQIGSGQVAKLTNNMLMGIT 719
+ A+ TL + G D + +L+ G + H G +G+ K N+ +
Sbjct: 120 TIGPAEAGTLRVLVGAADADLAAARGILETFGDPGRIDHVGPVGAASALKTVFNLGLAEA 179
Query: 720 GMAXAECMXMGIKMGLXPKVLLDVL 794
A AE + G ++G+ +LL L
Sbjct: 180 TAAAAEVLRYGTELGVDRSLLLSEL 204
>UniRef50_A1UDJ6 Cluster: 6-phosphogluconate dehydrogenase,
NAD-binding precursor; n=7; Mycobacterium|Rep:
6-phosphogluconate dehydrogenase, NAD-binding precursor
- Mycobacterium sp. (strain KMS)
Length = 292
Score = 69.3 bits (162), Expect = 1e-10
Identities = 59/210 (28%), Positives = 85/210 (40%), Gaps = 1/210 (0%)
Frame = +3
Query: 180 KNVAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGVTPANSIXXXXXXXXXX 359
+ V +GLG MG +AA+L+ V +D D L + G A
Sbjct: 2 RRVGVIGLGGMGSALAASLLATDHYVVCFDIRPDVLRPIVELGAEAAADARELAGACDVV 61
Query: 360 XSILTSNKVVLDVYLGKD-GVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAP 536
+ L VL+V LG + GV+A G+ L+D ST +P V I G F D P
Sbjct: 62 LTFLPGPSQVLEVALGSERGVLAGLADGAALLDMSTCNPEVAAIIGQAYDAAGRRFVDCP 121
Query: 537 VSGGVMGAQNATLAFMAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMGI 716
VS A N T+ + GG +L + +CG G+G KL N +
Sbjct: 122 VS---RKAPNMTV--LVGGPSGVLGPDADVLAAVSRTLVYCGHRGAGYATKLLNQHIKYS 176
Query: 717 TGMAXAECMXMGIKMGLXPKVLLDVLNNSS 806
+A AE + + MGL + D + S
Sbjct: 177 WYLASAEALLIAEAMGLNAGEVADAIAECS 206
>UniRef50_Q1V2K7 Cluster: NADP oxidoreductase, coenzyme
F420-dependent:6- phosphogluconatedehydrogenase,
NAD-binding:3-hydroxyacyl-CoA; n=1; Candidatus
Pelagibacter ubique HTCC1002|Rep: NADP oxidoreductase,
coenzyme F420-dependent:6-
phosphogluconatedehydrogenase,
NAD-binding:3-hydroxyacyl-CoA - Candidatus Pelagibacter
ubique HTCC1002
Length = 284
Score = 68.9 bits (161), Expect = 2e-10
Identities = 52/213 (24%), Positives = 88/213 (41%), Gaps = 1/213 (0%)
Frame = +3
Query: 180 KNVAFLGLGNMGGFMAANLVK-KGFTVRGYDPSKDALNAAAKNGVTPANSIXXXXXXXXX 356
KNV F+G+G MG +A N++K K + ++ + G S
Sbjct: 2 KNVGFIGVGYMGYGIAKNILKNKNNLFVIANKNRSPIEKIVSEGAVEVKSYDELCSKDLD 61
Query: 357 XXSILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAP 536
+ +N + + K ++ +L+ID +T D N + I K + + + P
Sbjct: 62 CLFLCVTNTPIAHSIIEK--ILPLLNSDTLIIDITTHDQNGSIEANKIFKSKNINYIECP 119
Query: 537 VSGGVMGAQNATLAFMAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMGI 716
V GG + A+ L + GG +E+F+++ LK F+ G++G G +KL NN L
Sbjct: 120 VMGGPVQAEEGVLGGIIGGSEENFKKAEVFLKAFCKDYFYFGEVGMGTKSKLLNNFLTLG 179
Query: 717 TGMAXAECMXMGIKMGLXPKVLLDVLNNSSXRS 815
+ K + K L DV S S
Sbjct: 180 NATLIVHMIKGAKKFDIDLKKLYDVAKLGSGNS 212
>UniRef50_A5CN67 Cluster: Putative beta-hydroxyacid dehydrogenase;
n=1; Clavibacter michiganensis subsp. michiganensis
NCPPB 382|Rep: Putative beta-hydroxyacid dehydrogenase -
Clavibacter michiganensis subsp. michiganensis (strain
NCPPB 382)
Length = 291
Score = 68.9 bits (161), Expect = 2e-10
Identities = 49/204 (24%), Positives = 89/204 (43%), Gaps = 1/204 (0%)
Frame = +3
Query: 186 VAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGVTPANSIXXXXXXXXXXXS 365
+ LG G MG M+ ++++ G + ++ S + A G T A S
Sbjct: 1 MTLLGTGVMGSGMSRSILRAGLPLTVWNRSAEKAAPLADAGATVAESAADAVRDADVVVV 60
Query: 366 ILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAPVSG 545
+L VL+V V + G++++ SST+ ++I +A E + F DAPV G
Sbjct: 61 MLFDADAVLEVLAE---VAPALRPGAVVLQSSTVGVEGTRRIAALAAEHAVRFVDAPVLG 117
Query: 546 GVMGAQNATLAFMAGGRKEDFERSLPLLKVMGAKQFHCG-QIGSGQVAKLTNNMLMGITG 722
A+ L + G ++D + P+L+ G++ G G G KL N +
Sbjct: 118 TRGPAEQGLLVHLVSGSEDDLAVARPVLEATGSRTVVAGSDAGPGSALKLACNAWIASIT 177
Query: 723 MAXAECMXMGIKMGLXPKVLLDVL 794
A + + + +G+ P++ LD +
Sbjct: 178 AATGQSLGLARLLGVEPRLFLDAI 201
>UniRef50_A4FKN9 Cluster: 2-hydroxy-3-oxopropionate reductase; n=1;
Saccharopolyspora erythraea NRRL 2338|Rep:
2-hydroxy-3-oxopropionate reductase - Saccharopolyspora
erythraea (strain NRRL 23338)
Length = 297
Score = 68.9 bits (161), Expect = 2e-10
Identities = 52/207 (25%), Positives = 89/207 (42%), Gaps = 4/207 (1%)
Frame = +3
Query: 186 VAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGVTPANSIXXXXXXXXXXXS 365
V +GLG MG +A L + G V S+ AAA+ GV + +
Sbjct: 5 VGVIGLGPMGANLALRLAEAGLDVVATSRSQGTREAAAREGVRVVDDVRALAGRLRAASP 64
Query: 366 ---ILTSNKVVLDVYLG-KDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDA 533
++ S V DG++A + +++D+ST P + + +G DA
Sbjct: 65 KPVVVVSLPSGPQVRAAVVDGLLADGGE-FVVVDTSTCAPADARSLADDLHARGCAVVDA 123
Query: 534 PVSGGVMGAQNATLAFMAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMG 713
PVSGG A+ +L+ M GG + D + +++ + CG G+GQ+AK N +++
Sbjct: 124 PVSGGPTAARAGSLSVMVGGTEADVAAADEVIRAFAGRVVVCGGPGAGQIAKACNQLVVT 183
Query: 714 ITGMAXAECMXMGIKMGLXPKVLLDVL 794
AE + +G P + + L
Sbjct: 184 AGIAVVAEALVTASALGADPAAVREAL 210
>UniRef50_A0VSV4 Cluster: 6-phosphogluconate dehydrogenase,
NAD-binding precursor; n=1; Dinoroseobacter shibae DFL
12|Rep: 6-phosphogluconate dehydrogenase, NAD-binding
precursor - Dinoroseobacter shibae DFL 12
Length = 289
Score = 68.5 bits (160), Expect = 2e-10
Identities = 54/233 (23%), Positives = 92/233 (39%), Gaps = 1/233 (0%)
Frame = +3
Query: 186 VAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDA-LNAAAKNGVTPANSIXXXXXXXXXXX 362
V F+G+G MG MA L+ G V A L G A
Sbjct: 6 VGFIGVGMMGAGMAGCLLSAGHPVTLLAHRNRAPLTPLLDRGAREAPDAVTLLDGCDVLF 65
Query: 363 SILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAPVS 542
+ L + V + D ++ H + G + ID++T P + G F+DAPV+
Sbjct: 66 TCLPDAEAVAGL---ADTLLPHTRPGQIWIDTTTSRPETSATLAHRLDAAGAVFSDAPVT 122
Query: 543 GGVMGAQNATLAFMAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMGITG 722
GG AQ+ L + G F+ L+ G G+G AKL NN++ T
Sbjct: 123 GGPKQAQDGALTSLVGCAAAQFDTIASLVGTYSTAIRRFGDAGTGHAAKLLNNLVTQGTM 182
Query: 723 MAXAECMXMGIKMGLXPKVLLDVLNNSSXRSWSTXXVLSXPRTGAHRSVQYKL 881
+ ++ ++G+ P+ L +V+ + RS + + G + ++ +
Sbjct: 183 VLLSDAFQAAGRLGVDPRALYEVMMTGAARSGTLQKAVPPALDGDYTGARFSI 235
>UniRef50_A7I8V1 Cluster: 6-phosphogluconate dehydrogenase,
NAD-binding; n=1; Candidatus Methanoregula boonei
6A8|Rep: 6-phosphogluconate dehydrogenase, NAD-binding -
Methanoregula boonei (strain 6A8)
Length = 288
Score = 68.5 bits (160), Expect = 2e-10
Identities = 50/213 (23%), Positives = 95/213 (44%)
Frame = +3
Query: 177 DKNVAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGVTPANSIXXXXXXXXX 356
++ V +GLG++G +A L+ +G V ++ + A+ GV A S
Sbjct: 4 EQTVGCIGLGHLGHTIARRLIDQGVPVAVWNRTP---KKASDLGVPVAASPRDLVGRVDV 60
Query: 357 XXSILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAP 536
L + V V G +G+++ G ++ID++T + A + G + + P
Sbjct: 61 VLINLFDSDAVESVLSGPEGLLSGPCTGKIIIDTTTNHFGRVSDFYAGARDHGATYLECP 120
Query: 537 VSGGVMGAQNATLAFMAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMGI 716
V G V+ A L + G + +E PLL +G+ ++ G+ KL NN+++G
Sbjct: 121 VLGSVVPASQGKLTVLVSGDEGTYEVVKPLLSRIGSTLYYLGEPALATKMKLINNLVLGS 180
Query: 717 TGMAXAECMXMGIKMGLXPKVLLDVLNNSSXRS 815
AE + +G G+ ++D+L + + S
Sbjct: 181 FMATCAEAVALGEAAGIDRGEVIDILLSGAGNS 213
>UniRef50_A0K107 Cluster: 2-hydroxy-3-oxopropionate reductase; n=1;
Arthrobacter sp. FB24|Rep: 2-hydroxy-3-oxopropionate
reductase - Arthrobacter sp. (strain FB24)
Length = 302
Score = 68.1 bits (159), Expect = 3e-10
Identities = 54/196 (27%), Positives = 87/196 (44%), Gaps = 7/196 (3%)
Frame = +3
Query: 183 NVAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGV--TPANSIXXXXXXXXX 356
+VA +G G MG +A N++ + ++ + + A V TPA +
Sbjct: 17 SVALIGTGPMGAPIARNILAGHVPLTLWNRTAEKARAIGGGTVVATPAAAASEVVL---- 72
Query: 357 XXSILTSNKVVLDVYLGKDGVVAHAKKGSL----LIDSSTIDPNVPKQIFPIALEK-GLG 521
++L V + G+DG++A K + L+ T+ P + L GL
Sbjct: 73 --TVLPDLPQVAALLPGEDGLLAGWKAAGIEHPVLVIHGTVSPVAVAEFADDCLRNWGLT 130
Query: 522 FTDAPVSGGVMGAQNATLAFMAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNN 701
DAP+SGG +GA+ L+ M GG E ER PL + + H G+ G+G K N
Sbjct: 131 VVDAPLSGGTIGAEEGRLSIMVGGPAEAVERLTPLFGLYSSTAVHFGKTGAGSTVKACNQ 190
Query: 702 MLMGITGMAXAECMXM 749
+++ T A AE M +
Sbjct: 191 IVVAATVNALAEAMAL 206
>UniRef50_Q13VQ8 Cluster: Putative dehydrogenase/oxidoreductase
protein; n=2; Burkholderiales|Rep: Putative
dehydrogenase/oxidoreductase protein - Burkholderia
xenovorans (strain LB400)
Length = 300
Score = 67.7 bits (158), Expect = 4e-10
Identities = 48/204 (23%), Positives = 82/204 (40%)
Frame = +3
Query: 186 VAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGVTPANSIXXXXXXXXXXXS 365
V +G+G +G +A+NL+ G+ V GY +++ A G ++
Sbjct: 9 VGIIGIGQLGSAIASNLLDMGYRVVGYRRNRNEAQAFVDAGGELVDTPSLVVQQADFIFL 68
Query: 366 ILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAPVSG 545
L + V G G++ K G +++ T + G +A +SG
Sbjct: 69 CLPNESASNAVLEGVGGILPLLKDGKTVVEVGTYRKSFKLMQAEKIQATGANILEAELSG 128
Query: 546 GVMGAQNATLAFMAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMGITGM 725
F GG +E+ PLL+ + +F G G+ KL N L+ + +
Sbjct: 129 SPSLVLARKACFYVGGTDSVYEKCEPLLQAITDNRFFLGAFGTAVSMKLIANYLVTVNTL 188
Query: 726 AXAECMXMGIKMGLXPKVLLDVLN 797
A AE M +G + G P +L VL+
Sbjct: 189 AAAEAMNLGTRAGFSPDLLARVLS 212
>UniRef50_UPI0000D55E08 Cluster: PREDICTED: similar to CG4747-PA;
n=1; Tribolium castaneum|Rep: PREDICTED: similar to
CG4747-PA - Tribolium castaneum
Length = 267
Score = 67.3 bits (157), Expect = 5e-10
Identities = 45/156 (28%), Positives = 72/156 (46%), Gaps = 5/156 (3%)
Frame = +3
Query: 363 SILTSNKVVLDVYLGKDGVVAHAKKGSLL-----IDSSTIDPNVPKQIFPIALEKGLGFT 527
S L + +V +G GV+ A+ + L ++ ++IDP+ K I I KG +
Sbjct: 37 SCLADPRSAKEVVIGNCGVIHQAEGPAALAGKGYVEMTSIDPDTSKDICNIIESKGGRYL 96
Query: 528 DAPVSGGVMGAQNATLAFMAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNML 707
+A + G A++ +L +A G K F+ K +G F+ G +GS L NM
Sbjct: 97 EAQMQGSKKQAEDGSLIILAAGDKSLFDDCQTCFKAIGKTAFYLGTVGSATKMNLCINMA 156
Query: 708 MGITGMAXAECMXMGIKMGLXPKVLLDVLNNSSXRS 815
+GI AE M + + GL K L++ N S S
Sbjct: 157 LGIGLAGLAESMVLAERCGLSCKDFLEIFNLSEGAS 192
>UniRef50_Q5GUM4 Cluster: Dehydrogenase; n=5;
Gammaproteobacteria|Rep: Dehydrogenase - Xanthomonas
oryzae pv. oryzae
Length = 335
Score = 66.5 bits (155), Expect = 9e-10
Identities = 54/207 (26%), Positives = 88/207 (42%), Gaps = 1/207 (0%)
Frame = +3
Query: 186 VAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGVTPANSIXXXXXXXXXXXS 365
+ FLGLG MG MA NL++ GF + ++ S + G T S
Sbjct: 46 IGFLGLGTMGLPMAHNLLRGGFELSVWNRSPERAQPLRDAGATVVEQ-PCGAAHGPLLFS 104
Query: 366 ILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAPVSG 545
+L + V L + GV+ GS+ ++ +TI + + + E+G+ + APV G
Sbjct: 105 MLADDDAVRQTLLER-GVLDALPAGSVHVNMATISVALAHALTALHAERGVAYVAAPVLG 163
Query: 546 GVMGAQNATLAFMAGGRKEDFERSLPLLKVMGAKQFHCGQI-GSGQVAKLTNNMLMGITG 722
V A+ L +AGG R P+ +G K +H G+ AKL N+ +
Sbjct: 164 RVDVAEAGKLNILAGGDDVAVARVQPMFDALGQKTWHIGRAPEQANAAKLAANVCLASAI 223
Query: 723 MAXAECMXMGIKMGLXPKVLLDVLNNS 803
A AE + G+ L +L ++
Sbjct: 224 GAMAEASALARGHGVDTTQFLGMLTST 250
>UniRef50_Q01PV6 Cluster: 6-phosphogluconate dehydrogenase,
NAD-binding; n=1; Solibacter usitatus Ellin6076|Rep:
6-phosphogluconate dehydrogenase, NAD-binding -
Solibacter usitatus (strain Ellin6076)
Length = 267
Score = 66.5 bits (155), Expect = 9e-10
Identities = 53/198 (26%), Positives = 85/198 (42%)
Frame = +3
Query: 201 LGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGVTPANSIXXXXXXXXXXXSILTSN 380
+G +G +A L G+TV GYD L + G A + L ++
Sbjct: 1 MGLLGSAIADRLSAAGYTVVGYD-----LIPERRRGADSAQEVIGKCQTTFLC---LPTS 52
Query: 381 KVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAPVSGGVMGA 560
VV V G V A G ++D +T +P + + G+ + DA V G
Sbjct: 53 DVVAQVI----GSVKPAA-GITMVDCTTGEPESMAAMGEKLAKSGVDYLDATVLGSSKVV 107
Query: 561 QNATLAFMAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMGITGMAXAEC 740
++ MAGGR+E F+ + PL + ++ F+ G G+G KL N+ +G+ AE
Sbjct: 108 RSGAAVVMAGGRRESFDAASPLFRTFASRAFYLGPFGAGARMKLVVNLALGLHRAVLAET 167
Query: 741 MXMGIKMGLXPKVLLDVL 794
+ + P V L+VL
Sbjct: 168 LAFAHACEVSPTVALEVL 185
Database: uniref50
Posted date: Oct 5, 2007 11:19 AM
Number of letters in database: 575,637,011
Number of sequences in database: 1,657,284
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 944,744,762
Number of Sequences: 1657284
Number of extensions: 20453526
Number of successful extensions: 56807
Number of sequences better than 10.0: 369
Number of HSP's better than 10.0 without gapping: 53781
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 56572
length of database: 575,637,011
effective HSP length: 100
effective length of database: 409,908,611
effective search space used: 81571813589
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
- SilkBase 1999-2023 -