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Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= MFBP02_F_B06
         (900 letters)

Database: uniref50 
           1,657,284 sequences; 575,637,011 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

UniRef50_P48596 Cluster: GTP cyclohydrolase I; n=6; cellular org...   159   1e-37
UniRef50_Q19980 Cluster: GTP cyclohydrolase I; n=89; cellular or...   142   8e-33
UniRef50_P30793 Cluster: GTP cyclohydrolase I; n=78; cellular or...   141   2e-32
UniRef50_A6QSY1 Cluster: GTP cyclohydrolase I; n=3; cellular org...   126   8e-28
UniRef50_P51599 Cluster: GTP cyclohydrolase I; n=14; Ascomycota|...   124   3e-27
UniRef50_Q4SEZ7 Cluster: Chromosome 1 SCAF14609, whole genome sh...   123   7e-27
UniRef50_Q6F9M5 Cluster: GTP cyclohydrolase I; n=3; cellular org...   120   4e-26
UniRef50_Q94465 Cluster: GTP cyclohydrolase I; n=2; Dictyosteliu...   120   4e-26
UniRef50_Q8KEA8 Cluster: GTP cyclohydrolase I; n=46; Bacteria|Re...   116   8e-25
UniRef50_Q2GYY2 Cluster: Putative uncharacterized protein; n=1; ...   116   1e-24
UniRef50_Q8YLL1 Cluster: GTP cyclohydrolase I 1; n=29; Bacteria|...   115   2e-24
UniRef50_A5WE14 Cluster: GTP cyclohydrolase I; n=4; Pseudomonada...   108   2e-22
UniRef50_Q9RYB4 Cluster: GTP cyclohydrolase I; n=5; Bacteria|Rep...   103   5e-21
UniRef50_A5UR68 Cluster: GTP cyclohydrolase I; n=7; Bacteria|Rep...    99   1e-19
UniRef50_A6RNT4 Cluster: Putative uncharacterized protein; n=2; ...    93   9e-18
UniRef50_Q2Q448 Cluster: GTP cyclohydrolase I; n=1; Toxoplasma g...    87   4e-16
UniRef50_Q7VFG4 Cluster: GTP cyclohydrolase I; n=6; Helicobacter...    87   4e-16
UniRef50_A6SZ52 Cluster: GTP cyclohydrolase I; n=2; root|Rep: GT...    85   3e-15
UniRef50_Q8G0L4 Cluster: GTP cyclohydrolase I; n=20; Bacteria|Re...    85   3e-15
UniRef50_Q8G3S1 Cluster: GTP cyclohydrolase I; n=4; Bifidobacter...    84   5e-15
UniRef50_P0C0C1 Cluster: GTP cyclohydrolase I; n=23; Bacteria|Re...    82   2e-14
UniRef50_A4G565 Cluster: GTP cyclohydrolase I; n=2; Betaproteoba...    81   4e-14
UniRef50_A7QSC6 Cluster: Chromosome chr3 scaffold_158, whole gen...    80   9e-14
UniRef50_Q3WEZ6 Cluster: GTP cyclohydrolase I; n=7; Bacteria|Rep...    79   2e-13
UniRef50_Q82Z12 Cluster: GTP cyclohydrolase I; n=1; Enterococcus...    78   4e-13
UniRef50_Q5NN57 Cluster: GTP cyclohydrolase I; n=4; Sphingomonad...    77   5e-13
UniRef50_Q6NF93 Cluster: GTP cyclohydrolase I; n=8; Bacteria|Rep...    77   6e-13
UniRef50_Q89IW2 Cluster: GTP cyclohydrolase I; n=13; Bacteria|Re...    77   6e-13
UniRef50_O69531 Cluster: GTP cyclohydrolase I; n=98; Bacteria|Re...    77   8e-13
UniRef50_A2U8J6 Cluster: GTP cyclohydrolase I; n=2; Bacillus|Rep...    76   1e-12
UniRef50_Q1IAJ6 Cluster: Putative GTP cyclohydrolase I; n=1; Pse...    75   2e-12
UniRef50_Q68WZ4 Cluster: GTP cyclohydrolase 1; n=25; Bacteria|Re...    74   4e-12
UniRef50_A5EFZ1 Cluster: GTP cyclohydrolase I; n=6; Proteobacter...    73   1e-11
UniRef50_Q92QB4 Cluster: GTP cyclohydrolase I; n=49; Proteobacte...    73   1e-11
UniRef50_A0RYT5 Cluster: GTP cyclohydrolase I; n=2; Thermoprotei...    70   7e-11
UniRef50_Q8T649 Cluster: GTP cyclohydrolase I; n=3; Plasmodium y...    70   9e-11
UniRef50_UPI0000DADB56 Cluster: hypothetical protein RcanM_01000...    69   1e-10
UniRef50_Q88ST4 Cluster: GTP cyclohydrolase I; n=11; Lactobacill...    69   1e-10
UniRef50_Q5HBC9 Cluster: GTP cyclohydrolase I; n=4; canis group|...    69   2e-10
UniRef50_Q9PC02 Cluster: GTP cyclohydrolase I; n=16; Bacteria|Re...    69   2e-10
UniRef50_A5Z385 Cluster: Putative uncharacterized protein; n=1; ...    69   2e-10
UniRef50_A2BL58 Cluster: GTP cyclohydrolase I; n=2; Thermoprotei...    68   3e-10
UniRef50_Q6SIF0 Cluster: GTP cyclohydrolase I; n=1; Plasmodium k...    68   4e-10
UniRef50_Q01A10 Cluster: GTP cyclohydrolase I; n=2; Ostreococcus...    66   1e-09
UniRef50_Q8S3C2 Cluster: GTP cyclohydrolase I; n=7; core eudicot...    65   3e-09
UniRef50_A4CGT7 Cluster: GTP cyclohydrolase I; n=1; Robiginitale...    64   4e-09
UniRef50_A5K040 Cluster: GTP cyclohydrolase I, putative; n=1; Pl...    64   5e-09
UniRef50_O97071 Cluster: GTP cyclohydrolase I; n=6; Plasmodium|R...    62   1e-08
UniRef50_Q2GK14 Cluster: GTP cyclohydrolase I; n=2; Anaplasma ph...    62   2e-08
UniRef50_Q0CVT9 Cluster: GTP cyclohydrolase I; n=1; Aspergillus ...    62   2e-08
UniRef50_Q97D54 Cluster: GTP cyclohydrolase I; n=7; Clostridium|...    61   3e-08
UniRef50_Q2JC68 Cluster: GTP cyclohydrolase I; n=1; Frankia sp. ...    60   8e-08
UniRef50_Q8RH43 Cluster: GTP cyclohydrolase I; n=3; Fusobacteriu...    59   2e-07
UniRef50_A1SM21 Cluster: GTP cyclohydrolase I precursor; n=7; Ac...    58   2e-07
UniRef50_A4QTK3 Cluster: Putative uncharacterized protein; n=1; ...    58   2e-07
UniRef50_Q8ZWW5 Cluster: GTP cyclohydrolase I; n=4; Pyrobaculum|...    58   4e-07
UniRef50_Q971G9 Cluster: GTP cyclohydrolase I; n=4; Sulfolobacea...    57   5e-07
UniRef50_Q6MK87 Cluster: FolE protein; n=1; Bdellovibrio bacteri...    57   7e-07
UniRef50_UPI00015BB290 Cluster: GTP cyclohydrolase; n=1; Ignicoc...    56   1e-06
UniRef50_Q8ZG15 Cluster: GTP cyclohydrolase I; n=129; root|Rep: ...    56   2e-06
UniRef50_Q6ME26 Cluster: Probable GTP cyclohydrolase I; n=1; Can...    55   2e-06
UniRef50_UPI000038E307 Cluster: hypothetical protein Faci_030017...    54   4e-06
UniRef50_Q5PAR5 Cluster: GTP cyclohydrolase; n=1; Anaplasma marg...    54   5e-06
UniRef50_Q5V5Y0 Cluster: GTP cyclohydrolase I; n=1; Haloarcula m...    54   7e-06
UniRef50_Q23AG3 Cluster: GTP cyclohydrolase I family protein; n=...    51   3e-05
UniRef50_Q1FI35 Cluster: GTP cyclohydrolase I; n=1; Clostridium ...    51   5e-05
UniRef50_A3J0S0 Cluster: GTP cyclohydrolase I; n=28; Bacteroidet...    50   1e-04
UniRef50_Q1Q0A8 Cluster: Strongly similar to GTP cyclohydrolase ...    49   2e-04
UniRef50_Q08SR8 Cluster: GTP cyclohydrolase I 2; n=2; Cystobacte...    49   2e-04
UniRef50_Q19Z80 Cluster: Gp6; n=4; root|Rep: Gp6 - Mycobacterium...    49   2e-04
UniRef50_Q83FV8 Cluster: GTP cyclohydrolase I; n=2; Tropheryma w...    48   3e-04
UniRef50_Q54768 Cluster: Putative uncharacterized protein; n=1; ...    47   6e-04
UniRef50_Q8XZK8 Cluster: GTP cyclohydrolase I; n=29; Betaproteob...    47   6e-04
UniRef50_A7HBJ5 Cluster: GTP cyclohydrolase I; n=2; Anaeromyxoba...    47   8e-04
UniRef50_Q7XM20 Cluster: OSJNBa0084K01.11 protein; n=4; Oryza sa...    46   0.002
UniRef50_Q2GDH9 Cluster: GTP cyclohydrolase I; n=1; Neorickettsi...    45   0.002
UniRef50_A5GUC6 Cluster: GTP cyclohydrolase I; n=28; Cyanobacter...    42   0.028
UniRef50_UPI0000F1DBDC Cluster: PREDICTED: similar to GTP cycloh...    41   0.049
UniRef50_A7JLM6 Cluster: GTP cyclohydrolase I; n=11; Francisella...    39   0.15 
UniRef50_A4SVK2 Cluster: GTP cyclohydrolase I; n=20; Bacteria|Re...    39   0.15 
UniRef50_Q7N3C4 Cluster: Similarities with GTP cyclohydrolase I;...    36   1.4  
UniRef50_A7INF0 Cluster: Rare lipoprotein A; n=1; Xanthobacter a...    35   2.5  
UniRef50_Q5AW97 Cluster: Putative uncharacterized protein; n=1; ...    35   2.5  
UniRef50_Q02495 Cluster: Homeodomain protein; n=1; Schizophyllum...    35   3.3  
UniRef50_UPI00015B6146 Cluster: PREDICTED: similar to ENSANGP000...    34   5.7  
UniRef50_UPI00006C1A5A Cluster: PREDICTED: hypothetical protein;...    34   5.7  
UniRef50_A6RXW6 Cluster: Putative uncharacterized protein; n=1; ...    34   5.7  
UniRef50_UPI00005A0D93 Cluster: PREDICTED: similar to Zinc finge...    33   7.5  
UniRef50_Q9AB50 Cluster: Hydrolase, alpha/beta hydrolase fold fa...    33   7.5  
UniRef50_Q74K42 Cluster: Levansucrase; n=1; Lactobacillus johnso...    33   7.5  
UniRef50_A6Q395 Cluster: 2-oxoglutarate ferredoxin oxidoreductas...    33   7.5  
UniRef50_A3YCH8 Cluster: Lipid A biosynthesis acyltransferase; n...    33   7.5  
UniRef50_A5AVA6 Cluster: Putative uncharacterized protein; n=3; ...    33   9.9  

>UniRef50_P48596 Cluster: GTP cyclohydrolase I; n=6; cellular
           organisms|Rep: GTP cyclohydrolase I - Drosophila
           melanogaster (Fruit fly)
          Length = 324

 Score =  159 bits (385), Expect = 1e-37
 Identities = 79/107 (73%), Positives = 85/107 (79%)
 Frame = +1

Query: 580 QGLLKTPERAAKAMLFFTKGYXQSLEEVLNNAIFDEDTDEMVVVKDIEMFSMCEHHLVPF 759
           QGL+KTPERAAKAML+FTKGY QSLE+VLN A+FDED DEMVVVKDIEMFSMCEHHLVPF
Sbjct: 162 QGLIKTPERAAKAMLYFTKGYDQSLEDVLNGAVFDEDHDEMVVVKDIEMFSMCEHHLVPF 221

Query: 760 YGKVSIGYLPQGXILGLSNWPGSWKYSPAGLQVXXRLTXXIAIAXTQ 900
           YGKVSIGYLP   ILGLS      +     LQV  RLT  IA+A TQ
Sbjct: 222 YGKVSIGYLPCNKILGLSKLARIVEIFSRRLQVQERLTKQIAVAVTQ 268



 Score =  121 bits (291), Expect = 3e-26
 Identities = 53/80 (66%), Positives = 63/80 (78%)
 Frame = +3

Query: 354 PEALKSFNLADAESELEVPGTPMTPRTSTTPGHENCTFHHDLELDHRPPTREALLPDMAN 533
           P  +   N +  +S+   P TP+TPRTSTTPGHE CTFHHDLELDH+PPTREALLPDMA 
Sbjct: 87  PRLILKTNGSSPDSDGTQPKTPLTPRTSTTPGHEKCTFHHDLELDHKPPTREALLPDMAR 146

Query: 534 SYRLLLTGLGEDPERAGALE 593
           SYRLLL GLGE+P+R G ++
Sbjct: 147 SYRLLLGGLGENPDRQGLIK 166


>UniRef50_Q19980 Cluster: GTP cyclohydrolase I; n=89; cellular
           organisms|Rep: GTP cyclohydrolase I - Caenorhabditis
           elegans
          Length = 223

 Score =  142 bits (345), Expect = 8e-33
 Identities = 70/113 (61%), Positives = 80/113 (70%)
 Frame = +1

Query: 562 GRTLKGQGLLKTPERAAKAMLFFTKGYXQSLEEVLNNAIFDEDTDEMVVVKDIEMFSMCE 741
           G  +  QGLLKTPERAAKAM+ FTKGY   L+E+LN A+FDED DEMV+VKDIEMFS+CE
Sbjct: 55  GEDINRQGLLKTPERAAKAMMAFTKGYDDQLDELLNEAVFDEDHDEMVIVKDIEMFSLCE 114

Query: 742 HHLVPFYGKVSIGYLPQGXILGLSNWPGSWKYSPAGLQVXXRLTXXIAIAXTQ 900
           HHLVPF GKV IGY+P   +LGLS      +     LQV  RLT  IA A  Q
Sbjct: 115 HHLVPFMGKVHIGYIPNKKVLGLSKLARIVEMFSRRLQVQERLTKQIATAMVQ 167


>UniRef50_P30793 Cluster: GTP cyclohydrolase I; n=78; cellular
           organisms|Rep: GTP cyclohydrolase I - Homo sapiens
           (Human)
          Length = 250

 Score =  141 bits (342), Expect = 2e-32
 Identities = 70/113 (61%), Positives = 82/113 (72%)
 Frame = +1

Query: 562 GRTLKGQGLLKTPERAAKAMLFFTKGYXQSLEEVLNNAIFDEDTDEMVVVKDIEMFSMCE 741
           G   + QGLLKTP RAA AM FFTKGY +++ +VLN+AIFDED DEMV+VKDI+MFSMCE
Sbjct: 83  GENPQRQGLLKTPWRAASAMQFFTKGYQETISDVLNDAIFDEDHDEMVIVKDIDMFSMCE 142

Query: 742 HHLVPFYGKVSIGYLPQGXILGLSNWPGSWKYSPAGLQVXXRLTXXIAIAXTQ 900
           HHLVPF GKV IGYLP   +LGLS      +     LQV  RLT  IA+A T+
Sbjct: 143 HHLVPFVGKVHIGYLPNKQVLGLSKLARIVEIYSRRLQVQERLTKQIAVAITE 195


>UniRef50_A6QSY1 Cluster: GTP cyclohydrolase I; n=3; cellular
           organisms|Rep: GTP cyclohydrolase I - Ajellomyces
           capsulatus NAm1
          Length = 390

 Score =  126 bits (304), Expect = 8e-28
 Identities = 57/113 (50%), Positives = 82/113 (72%)
 Frame = +1

Query: 562 GRTLKGQGLLKTPERAAKAMLFFTKGYXQSLEEVLNNAIFDEDTDEMVVVKDIEMFSMCE 741
           G   + +GLL TPER AKA+++FTKGY +++ +++N A+F ED DE+V+VKDIE+FS+CE
Sbjct: 222 GEDPEREGLLGTPERYAKALMYFTKGYEENVRDLVNGAVFHEDHDELVIVKDIEIFSLCE 281

Query: 742 HHLVPFYGKVSIGYLPQGXILGLSNWPGSWKYSPAGLQVXXRLTXXIAIAXTQ 900
           HHLVPF GK+ IGY+P   +LGLS +    +     LQV  RLT  +A+A ++
Sbjct: 282 HHLVPFTGKMHIGYIPDRRVLGLSKFARLAEMFSRRLQVQERLTKQVALAISE 334


>UniRef50_P51599 Cluster: GTP cyclohydrolase I; n=14;
           Ascomycota|Rep: GTP cyclohydrolase I - Neurospora crassa
          Length = 313

 Score =  124 bits (299), Expect = 3e-27
 Identities = 57/104 (54%), Positives = 75/104 (72%)
 Frame = +1

Query: 580 QGLLKTPERAAKAMLFFTKGYXQSLEEVLNNAIFDEDTDEMVVVKDIEMFSMCEHHLVPF 759
           +GLL TPER AKAMLF TKGY +++ +++N AIF E  +EMV+VKDIE+FSMCEHHLVPF
Sbjct: 150 EGLLATPERYAKAMLFLTKGYQENVRDIVNGAIFQEGHNEMVIVKDIEVFSMCEHHLVPF 209

Query: 760 YGKVSIGYLPQGXILGLSNWPGSWKYSPAGLQVXXRLTXXIAIA 891
            GK+ IGY+P   ++G+S  P   +     LQ+  RLT  +A A
Sbjct: 210 TGKMHIGYIPSNAVIGISKLPRIAELFARRLQIQERLTKEVANA 253


>UniRef50_Q4SEZ7 Cluster: Chromosome 1 SCAF14609, whole genome
           shotgun sequence; n=2; Tetraodontidae|Rep: Chromosome 1
           SCAF14609, whole genome shotgun sequence - Tetraodon
           nigroviridis (Green puffer)
          Length = 263

 Score =  123 bits (296), Expect = 7e-27
 Identities = 60/113 (53%), Positives = 77/113 (68%)
 Frame = +1

Query: 562 GRTLKGQGLLKTPERAAKAMLFFTKGYXQSLEEVLNNAIFDEDTDEMVVVKDIEMFSMCE 741
           G     +GL +TP RAAKAM F TKGY +S++E+LN+AIFDE+  E+V+VKDIEMFS+CE
Sbjct: 51  GEDATREGLQRTPLRAAKAMQFLTKGYNESVKEILNDAIFDENHQEVVIVKDIEMFSLCE 110

Query: 742 HHLVPFYGKVSIGYLPQGXILGLSNWPGSWKYSPAGLQVXXRLTXXIAIAXTQ 900
           HHLVPF+GK  I YLP   ++GLS      +      QV  RLT  IA A ++
Sbjct: 111 HHLVPFFGKAHIAYLPNKKVVGLSKLARIVEVYSRRFQVQERLTKQIASAISE 163


>UniRef50_Q6F9M5 Cluster: GTP cyclohydrolase I; n=3; cellular
           organisms|Rep: GTP cyclohydrolase I - Acinetobacter sp.
           (strain ADP1)
          Length = 197

 Score =  120 bits (290), Expect = 4e-26
 Identities = 60/112 (53%), Positives = 73/112 (65%)
 Frame = +1

Query: 556 AWGRTLKGQGLLKTPERAAKAMLFFTKGYXQSLEEVLNNAIFDEDTDEMVVVKDIEMFSM 735
           A G  L   GL  TP RAAKA  F T GY +SLEEV NNA+F  D  EMV+VK+IE +S+
Sbjct: 26  AVGEDLNRPGLKDTPIRAAKAFSFLTSGYGKSLEEVTNNAVFPSDNHEMVLVKNIEFYSL 85

Query: 736 CEHHLVPFYGKVSIGYLPQGXILGLSNWPGSWKYSPAGLQVXXRLTXXIAIA 891
           CEHHL+PFYG+V I YLP+G +LGLS +    +     LQ+   LT  IA A
Sbjct: 86  CEHHLLPFYGRVHIAYLPEGQVLGLSKFARITEMFARRLQIQENLTQQIAQA 137


>UniRef50_Q94465 Cluster: GTP cyclohydrolase I; n=2; Dictyostelium
           discoideum|Rep: GTP cyclohydrolase I - Dictyostelium
           discoideum (Slime mold)
          Length = 232

 Score =  120 bits (290), Expect = 4e-26
 Identities = 58/104 (55%), Positives = 76/104 (73%)
 Frame = +1

Query: 580 QGLLKTPERAAKAMLFFTKGYXQSLEEVLNNAIFDEDTDEMVVVKDIEMFSMCEHHLVPF 759
           +GLLKTP R +KA+LFFT+GY QS++EV+  AIF+E+  EMVVV+DI++FS+CEHH+VPF
Sbjct: 69  EGLLKTPLRMSKALLFFTQGYEQSVDEVIGEAIFNENHHEMVVVRDIDIFSLCEHHMVPF 128

Query: 760 YGKVSIGYLPQGXILGLSNWPGSWKYSPAGLQVXXRLTXXIAIA 891
           +GK  IGY+P   +LGLS      +     LQV  RLT  IA A
Sbjct: 129 HGKCHIGYIPDQKVLGLSKLARVAEIFARRLQVQERLTRQIAQA 172


>UniRef50_Q8KEA8 Cluster: GTP cyclohydrolase I; n=46; Bacteria|Rep:
           GTP cyclohydrolase I - Chlorobium tepidum
          Length = 224

 Score =  116 bits (279), Expect = 8e-25
 Identities = 54/107 (50%), Positives = 72/107 (67%)
 Frame = +1

Query: 562 GRTLKGQGLLKTPERAAKAMLFFTKGYXQSLEEVLNNAIFDEDTDEMVVVKDIEMFSMCE 741
           G   + +GLL TPER AK++ F TKGY Q  E++L  A+F E  DEMV+VKDI+++SMCE
Sbjct: 56  GEDPEREGLLLTPERVAKSLRFLTKGYRQDPEQLLKKAVFTESYDEMVLVKDIDIYSMCE 115

Query: 742 HHLVPFYGKVSIGYLPQGXILGLSNWPGSWKYSPAGLQVXXRLTXXI 882
           HH++PF+GK  + Y+P G I+GLS  P   +     LQV  RLT  I
Sbjct: 116 HHMLPFFGKAHVAYIPDGKIVGLSKIPRVVEVFARRLQVQERLTQQI 162


>UniRef50_Q2GYY2 Cluster: Putative uncharacterized protein; n=1;
           Chaetomium globosum|Rep: Putative uncharacterized
           protein - Chaetomium globosum (Soil fungus)
          Length = 233

 Score =  116 bits (278), Expect = 1e-24
 Identities = 51/101 (50%), Positives = 72/101 (71%)
 Frame = +1

Query: 583 GLLKTPERAAKAMLFFTKGYXQSLEEVLNNAIFDEDTDEMVVVKDIEMFSMCEHHLVPFY 762
           G+L TPER AKAM+F T+GY Q++ E++NNAIF E   EMV+VKDI++FS+CEHH++PF 
Sbjct: 109 GVLNTPERYAKAMMFLTQGYGQNIHEIVNNAIFHEGHHEMVIVKDIDIFSICEHHMLPFI 168

Query: 763 GKVSIGYLPQGXILGLSNWPGSWKYSPAGLQVXXRLTXXIA 885
           GK+ I Y+P   ++G+S  P   +     LQ+  RLT  +A
Sbjct: 169 GKMHIAYIPYHSVIGISKLPRIAEMFSRRLQIQERLTKDVA 209


>UniRef50_Q8YLL1 Cluster: GTP cyclohydrolase I 1; n=29;
           Bacteria|Rep: GTP cyclohydrolase I 1 - Anabaena sp.
           (strain PCC 7120)
          Length = 235

 Score =  115 bits (276), Expect = 2e-24
 Identities = 55/110 (50%), Positives = 73/110 (66%)
 Frame = +1

Query: 562 GRTLKGQGLLKTPERAAKAMLFFTKGYXQSLEEVLNNAIFDEDTDEMVVVKDIEMFSMCE 741
           G   + +GLLKTP+R A+AM F T GY QSLEE+LN A+FDE  +EMV+V+DI  FS+CE
Sbjct: 63  GEDPEREGLLKTPKRVAEAMRFLTSGYNQSLEELLNGAVFDEGHNEMVLVRDINFFSLCE 122

Query: 742 HHLVPFYGKVSIGYLPQGXILGLSNWPGSWKYSPAGLQVXXRLTXXIAIA 891
           HH++PF G+  + Y+P   ++GLS      +     LQV  RLT  IA A
Sbjct: 123 HHMLPFMGRAHVAYIPNQKVVGLSKLARIVEMYSRRLQVQERLTRQIAEA 172



 Score = 33.1 bits (72), Expect = 9.9
 Identities = 17/54 (31%), Positives = 28/54 (51%)
 Frame = +3

Query: 468 HHDLELDHRPPTREALLPDMANSYRLLLTGLGEDPERAGALEDARTCRQSYALL 629
           H+  E +   P+ E +   M  + R +L G+GEDPER G L+  +   ++   L
Sbjct: 33  HNGREPELHQPSEEDM-ESMMGAVRSILVGVGEDPEREGLLKTPKRVAEAMRFL 85


>UniRef50_A5WE14 Cluster: GTP cyclohydrolase I; n=4;
           Pseudomonadales|Rep: GTP cyclohydrolase I -
           Psychrobacter sp. PRwf-1
          Length = 201

 Score =  108 bits (259), Expect = 2e-22
 Identities = 53/110 (48%), Positives = 68/110 (61%)
 Frame = +1

Query: 562 GRTLKGQGLLKTPERAAKAMLFFTKGYXQSLEEVLNNAIFDEDTDEMVVVKDIEMFSMCE 741
           G  L   GLL TP RAAKA  + T+GY QSL EV NNA+F  D  E+V+V +IE +S+CE
Sbjct: 31  GEDLNRPGLLDTPTRAAKAFGYLTQGYHQSLTEVTNNAVFPTDNSELVLVHNIEFYSLCE 90

Query: 742 HHLVPFYGKVSIGYLPQGXILGLSNWPGSWKYSPAGLQVXXRLTXXIAIA 891
           HHL+PF+G   +GYLP G +LGLS            LQ+   L+  +A A
Sbjct: 91  HHLLPFHGVAHVGYLPDGKVLGLSKVARIIDMYARRLQIQESLSQQVAEA 140


>UniRef50_Q9RYB4 Cluster: GTP cyclohydrolase I; n=5; Bacteria|Rep:
           GTP cyclohydrolase I - Deinococcus radiodurans
          Length = 216

 Score =  103 bits (248), Expect = 5e-21
 Identities = 47/104 (45%), Positives = 67/104 (64%)
 Frame = +1

Query: 580 QGLLKTPERAAKAMLFFTKGYXQSLEEVLNNAIFDEDTDEMVVVKDIEMFSMCEHHLVPF 759
           +GL +TP+R AKA  + T+GY Q+L +V+   +F  +  EMV+VKDIE +SMCEHH++PF
Sbjct: 50  EGLQRTPQRVAKAWAYMTEGYGQTLAQVVGEGVFAAEGSEMVIVKDIEFYSMCEHHMLPF 109

Query: 760 YGKVSIGYLPQGXILGLSNWPGSWKYSPAGLQVXXRLTXXIAIA 891
           YG+  + Y+P   ILGLS +          LQV  R+T  +A A
Sbjct: 110 YGRAHVAYIPGTRILGLSKFARIVDLYSRRLQVQERITTQVADA 153


>UniRef50_A5UR68 Cluster: GTP cyclohydrolase I; n=7; Bacteria|Rep:
           GTP cyclohydrolase I - Roseiflexus sp. RS-1
          Length = 226

 Score = 99.1 bits (236), Expect = 1e-19
 Identities = 48/108 (44%), Positives = 66/108 (61%)
 Frame = +1

Query: 562 GRTLKGQGLLKTPERAAKAMLFFTKGYXQSLEEVLNNAIFDEDTDEMVVVKDIEMFSMCE 741
           G   + +GLLKTP R AK     T GY    + ++N+AIF    DEMV+VK+IE  S+CE
Sbjct: 58  GENPEREGLLKTPSRVAKMYAELTAGYHIDPDALINDAIFSVSYDEMVLVKNIEFASLCE 117

Query: 742 HHLVPFYGKVSIGYLPQGXILGLSNWPGSWKYSPAGLQVXXRLTXXIA 885
           HH++PF G+V + Y+P G ++GLS  P   +     LQV  R+T  IA
Sbjct: 118 HHMLPFMGRVHVAYIPNGKVVGLSKIPRIVEMFARRLQVQERMTVQIA 165


>UniRef50_A6RNT4 Cluster: Putative uncharacterized protein; n=2;
           Sclerotiniaceae|Rep: Putative uncharacterized protein -
           Botryotinia fuckeliana B05.10
          Length = 1504

 Score = 93.1 bits (221), Expect = 9e-18
 Identities = 38/69 (55%), Positives = 53/69 (76%)
 Frame = +1

Query: 562 GRTLKGQGLLKTPERAAKAMLFFTKGYXQSLEEVLNNAIFDEDTDEMVVVKDIEMFSMCE 741
           G      GL KTPER AKA+ FFT+GY +   E++N AIF+EDT++MV+V  I++FS+CE
Sbjct: 111 GEDTNRDGLKKTPERYAKALQFFTQGYKEKSNELINGAIFNEDTEDMVIVSGIDVFSLCE 170

Query: 742 HHLVPFYGK 768
           HH++PF+GK
Sbjct: 171 HHMLPFFGK 179


>UniRef50_Q2Q448 Cluster: GTP cyclohydrolase I; n=1; Toxoplasma
           gondii|Rep: GTP cyclohydrolase I - Toxoplasma gondii
          Length = 262

 Score = 87.4 bits (207), Expect = 4e-16
 Identities = 49/123 (39%), Positives = 71/123 (57%), Gaps = 11/123 (8%)
 Frame = +1

Query: 556 AWGRTLKGQGLLKTPERAAKAMLFFTKGYXQSLEEVLNNAIFD-EDTDE----------M 702
           A G  +   GL +TP+R A AM FF++GY    ++V+ NA+F  E+  E          M
Sbjct: 76  AMGEDVTRAGLRETPKRVAAAMEFFSRGYRADPKDVIRNALFSVEEGHEDGQYLAGKQGM 135

Query: 703 VVVKDIEMFSMCEHHLVPFYGKVSIGYLPQGXILGLSNWPGSWKYSPAGLQVXXRLTXXI 882
           V V  I++ S+CEHHL+PF+GK  IGY+P   +LG+S +    +     LQ+  RLT  I
Sbjct: 136 VTVGRIDISSLCEHHLLPFFGKCHIGYIPDKHVLGISKFARIMEIYSRRLQIQERLTQQI 195

Query: 883 AIA 891
           A+A
Sbjct: 196 ALA 198


>UniRef50_Q7VFG4 Cluster: GTP cyclohydrolase I; n=6;
           Helicobacter|Rep: GTP cyclohydrolase I - Helicobacter
           hepaticus
          Length = 206

 Score = 87.4 bits (207), Expect = 4e-16
 Identities = 42/104 (40%), Positives = 62/104 (59%)
 Frame = +1

Query: 580 QGLLKTPERAAKAMLFFTKGYXQSLEEVLNNAIFDEDTDEMVVVKDIEMFSMCEHHLVPF 759
           +GLL TP+R A A      GY +S ++ L +   D   DEM+V+K +  +S+CEHHL+PF
Sbjct: 46  EGLLHTPKRIASAFSDMLNGYAKSPKQALGSVFEDGVCDEMIVLKKLHFYSICEHHLLPF 105

Query: 760 YGKVSIGYLPQGXILGLSNWPGSWKYSPAGLQVXXRLTXXIAIA 891
           +G +SIGY+P   ++G+S      +     LQ+  RLT  IA A
Sbjct: 106 FGHISIGYIPDKKLVGISGLARLTEVFTHRLQIQERLTAQIADA 149


>UniRef50_A6SZ52 Cluster: GTP cyclohydrolase I; n=2; root|Rep: GTP
           cyclohydrolase I - Janthinobacterium sp. (strain
           Marseille) (Minibacterium massiliensis)
          Length = 198

 Score = 84.6 bits (200), Expect = 3e-15
 Identities = 47/111 (42%), Positives = 62/111 (55%), Gaps = 3/111 (2%)
 Frame = +1

Query: 562 GRTLKGQGLLKTPERAAKAMLFFTKGYXQSLEEVLNNAIFD---EDTDEMVVVKDIEMFS 732
           G     QGL +TP+R  KA   +T GY Q   E+L   +F+   E  +E++VV+ I ++S
Sbjct: 28  GENADRQGLRETPQRVEKAWKHWTSGYDQDPAEILK--VFEDGAEQYNELIVVRGIPVYS 85

Query: 733 MCEHHLVPFYGKVSIGYLPQGXILGLSNWPGSWKYSPAGLQVXXRLTXXIA 885
            CEHHL PF+G  +IGY P G I+GLS            LQV  RLT  IA
Sbjct: 86  HCEHHLAPFFGTATIGYTPNGKIVGLSKLTRLVDCFAKRLQVQERLTIQIA 136


>UniRef50_Q8G0L4 Cluster: GTP cyclohydrolase I; n=20; Bacteria|Rep:
           GTP cyclohydrolase I - Brucella suis
          Length = 213

 Score = 84.6 bits (200), Expect = 3e-15
 Identities = 42/80 (52%), Positives = 54/80 (67%), Gaps = 2/80 (2%)
 Frame = +1

Query: 580 QGLLKTPERAAKAMLFFTKGYXQSLEEVLNNAIFDEDT--DEMVVVKDIEMFSMCEHHLV 753
           +GLL+TP+R AKA      GY +S EEVL    F+E    D+MV+VKDI  FS CEHH+V
Sbjct: 51  EGLLETPKRVAKAYQELFGGYSESPEEVLGTT-FEEVAGYDDMVLVKDISFFSHCEHHMV 109

Query: 754 PFYGKVSIGYLPQGXILGLS 813
           P  GK  + YLP+G ++GLS
Sbjct: 110 PIIGKAHVAYLPEGRVVGLS 129


>UniRef50_Q8G3S1 Cluster: GTP cyclohydrolase I; n=4;
           Bifidobacterium|Rep: GTP cyclohydrolase I -
           Bifidobacterium longum
          Length = 199

 Score = 83.8 bits (198), Expect = 5e-15
 Identities = 46/114 (40%), Positives = 67/114 (58%), Gaps = 1/114 (0%)
 Frame = +1

Query: 562 GRTLKGQGLLKTPERAAKAMLFFTKGYXQSLEEVLNNAIFDEDTDEMVVVKDIEMFSMCE 741
           G   + +GL++TP+R A+A      G   S  + L    FD DTDE+V+VKDIE++S+CE
Sbjct: 32  GEDPEREGLVETPDRIARACRELFTGLQASPADALEKH-FDVDTDELVLVKDIELYSVCE 90

Query: 742 HHLVPFYGKVSIGYLP-QGXILGLSNWPGSWKYSPAGLQVXXRLTXXIAIAXTQ 900
           HHL+PF+G   +GY+P +  ++GLS      +      QV  RLT  IA A  +
Sbjct: 91  HHLLPFHGVAHVGYIPAKDGVMGLSKLARLVEVYARRPQVQERLTQQIADALVE 144


>UniRef50_P0C0C1 Cluster: GTP cyclohydrolase I; n=23; Bacteria|Rep:
           GTP cyclohydrolase I - Streptococcus pyogenes
          Length = 194

 Score = 82.2 bits (194), Expect = 2e-14
 Identities = 47/116 (40%), Positives = 63/116 (54%), Gaps = 1/116 (0%)
 Frame = +1

Query: 556 AWGRTLKGQGLLKTPERAAKAMLFFTKGYXQSLEEVLNNAIFDEDTDEMVVVKDIEMFSM 735
           A G     +GLL TP+R AK       G  +  +E    A+F E  +++V+VKDI  +SM
Sbjct: 24  AIGENPNREGLLDTPKRVAKMYAEMFAGLKKDPKEEFT-AVFTEHHEDVVIVKDISFYSM 82

Query: 736 CEHHLVPFYGKVSIGYLP-QGXILGLSNWPGSWKYSPAGLQVXXRLTXXIAIAXTQ 900
           CEHH VPFYGK  I YLP  G + GLS    + + +    Q+  RLT  IA A  +
Sbjct: 83  CEHHQVPFYGKAHIAYLPSDGRVTGLSKLARAVEVASKRPQLQERLTAQIADALVE 138


>UniRef50_A4G565 Cluster: GTP cyclohydrolase I; n=2;
           Betaproteobacteria|Rep: GTP cyclohydrolase I -
           Herminiimonas arsenicoxydans
          Length = 215

 Score = 81.0 bits (191), Expect = 4e-14
 Identities = 45/111 (40%), Positives = 61/111 (54%), Gaps = 3/111 (2%)
 Frame = +1

Query: 562 GRTLKGQGLLKTPERAAKAMLFFTKGYXQSLEEVLNNAIFDEDTD---EMVVVKDIEMFS 732
           G     QGL +TP+R  KA   +T GY Q   E+L   +F +  +   E+++V+ I ++S
Sbjct: 45  GENPNRQGLQETPKRVQKAWQQWTAGYAQDPAEILK--VFSDGAEQYKELIIVRGIPVYS 102

Query: 733 MCEHHLVPFYGKVSIGYLPQGXILGLSNWPGSWKYSPAGLQVXXRLTXXIA 885
            CEHHL PF+G  +IGY P G I+GLS            LQV  RLT  IA
Sbjct: 103 HCEHHLAPFFGTATIGYTPNGKIVGLSKLTRLVDCYARRLQVQERLTIQIA 153


>UniRef50_A7QSC6 Cluster: Chromosome chr3 scaffold_158, whole genome
           shotgun sequence; n=2; Vitis vinifera|Rep: Chromosome
           chr3 scaffold_158, whole genome shotgun sequence - Vitis
           vinifera (Grape)
          Length = 214

 Score = 79.8 bits (188), Expect = 9e-14
 Identities = 41/110 (37%), Positives = 65/110 (59%), Gaps = 2/110 (1%)
 Frame = +1

Query: 562 GRTLKGQGLLKTPERAAKAMLFFTKGYXQSLEEVLNNAIFDEDTDEMVVVKDIEMFSMCE 741
           G  +  +G+ KTP R AKA+   T+GY Q  ++++  A+F E    +V+V+D+++FS CE
Sbjct: 42  GEDINREGIRKTPARVAKALCEGTRGYRQKAKDIVQGALFPEAVGGLVIVRDLDLFSYCE 101

Query: 742 HHLVPFYGKVSIGYLPQG-XILGLSNWPGS-WKYSPAGLQVXXRLTXXIA 885
             L+PF  K  +GY+P G  ++GLS    S   +    LQV  RLT  ++
Sbjct: 102 SCLLPFQVKCHVGYVPSGQQVVGLSKLSRSIVHFYGFKLQVQERLTRQVS 151


>UniRef50_Q3WEZ6 Cluster: GTP cyclohydrolase I; n=7; Bacteria|Rep:
           GTP cyclohydrolase I - Frankia sp. EAN1pec
          Length = 257

 Score = 78.6 bits (185), Expect = 2e-13
 Identities = 46/106 (43%), Positives = 60/106 (56%), Gaps = 2/106 (1%)
 Frame = +1

Query: 580 QGLLKTPERAAKAMLFFTKGYXQSLEEVLNNAIFDEDTDEMVVVKDIEMFSMCEHHLVPF 759
           +GL KTP+R A+A     +G  +   EVL   +FDE  DEMV+V+DI+  S+CEHHLV F
Sbjct: 94  EGLRKTPDRVARAYQEAVEGLGRDPAEVLTT-VFDEGHDEMVLVRDIDFSSLCEHHLVVF 152

Query: 760 YGKVSIGYLP--QGXILGLSNWPGSWKYSPAGLQVXXRLTXXIAIA 891
            GK  + Y+P  +G I GLS             QV  RLT  +A A
Sbjct: 153 AGKAHVAYIPNEKGQITGLSKLARLVDLYARRPQVQERLTSQVADA 198


>UniRef50_Q82Z12 Cluster: GTP cyclohydrolase I; n=1; Enterococcus
           faecalis|Rep: GTP cyclohydrolase I - Enterococcus
           faecalis (Streptococcus faecalis)
          Length = 186

 Score = 77.8 bits (183), Expect = 4e-13
 Identities = 47/112 (41%), Positives = 62/112 (55%), Gaps = 2/112 (1%)
 Frame = +1

Query: 556 AWGRTLKGQGLLKTPERAAKAMLFFTKGYXQSLEEVLNNAIFDE-DTDEMVVVKDIEMFS 732
           A G   +  GL+ TP+R AK       G  +   E  +  +FD  +  EMV+VKDI  +S
Sbjct: 19  AVGEDTQRAGLIDTPKRVAKMYAEVFSGLTEP--EFDDYKLFDSLNEGEMVLVKDIAFYS 76

Query: 733 MCEHHLVPFYGKVSIGYLPQ-GXILGLSNWPGSWKYSPAGLQVXXRLTXXIA 885
           MCEHHL+PFYGKV + YLP+ G +LGLS  P   ++      V   LT  IA
Sbjct: 77  MCEHHLLPFYGKVHVAYLPEGGKVLGLSKLPRLVEHCAKRPTVQEDLTVTIA 128


>UniRef50_Q5NN57 Cluster: GTP cyclohydrolase I; n=4;
           Sphingomonadales|Rep: GTP cyclohydrolase I - Zymomonas
           mobilis
          Length = 220

 Score = 77.4 bits (182), Expect = 5e-13
 Identities = 40/104 (38%), Positives = 59/104 (56%), Gaps = 2/104 (1%)
 Frame = +1

Query: 580 QGLLKTPERAAKAMLFFTKGYXQSLEEVLNNAIFDE--DTDEMVVVKDIEMFSMCEHHLV 753
           +GL+ TP+R AKA  ++ +GY +  E  L   +F+E    D++V++KDI  +S CEHH+ 
Sbjct: 58  EGLIDTPKRVAKAWKYYCRGYREDPENHLKT-VFEEVGGYDDIVLLKDIPFYSHCEHHMA 116

Query: 754 PFYGKVSIGYLPQGXILGLSNWPGSWKYSPAGLQVXXRLTXXIA 885
           P  G   I YLP   ++GLS      K     LQ+  RLT  +A
Sbjct: 117 PIMGHAHIAYLPDKKVVGLSKLARVLKGYAHRLQIQERLTAQVA 160


>UniRef50_Q6NF93 Cluster: GTP cyclohydrolase I; n=8; Bacteria|Rep:
           GTP cyclohydrolase I - Corynebacterium diphtheriae
          Length = 190

 Score = 77.0 bits (181), Expect = 6e-13
 Identities = 46/106 (43%), Positives = 57/106 (53%), Gaps = 2/106 (1%)
 Frame = +1

Query: 580 QGLLKTPERAAKAMLFFTKGYXQSLEEVLNNAIFDEDTDEMVVVKDIEMFSMCEHHLVPF 759
           +GL +TP R AKA      G      EVL    F ED  E+V+V+DI ++S CEHHLVPF
Sbjct: 28  EGLQETPARVAKAYAEMFAGLHTDPTEVLAKT-FSEDHREVVLVRDIPIYSTCEHHLVPF 86

Query: 760 YGKVSIGYLP--QGXILGLSNWPGSWKYSPAGLQVXXRLTXXIAIA 891
           +GK  IGY+P   G + GLS             QV  RLT  +A A
Sbjct: 87  FGKAHIGYIPGESGKVTGLSKLARLVDLYAKRPQVQERLTTQVADA 132


>UniRef50_Q89IW2 Cluster: GTP cyclohydrolase I; n=13; Bacteria|Rep:
           GTP cyclohydrolase I - Bradyrhizobium japonicum
          Length = 229

 Score = 77.0 bits (181), Expect = 6e-13
 Identities = 45/112 (40%), Positives = 57/112 (50%), Gaps = 2/112 (1%)
 Frame = +1

Query: 562 GRTLKGQGLLKTPERAAKAMLFFTKGYXQSLEEVLNNAIFDEDT--DEMVVVKDIEMFSM 735
           G   + +GLL TP R  +A     +GY Q   EVL+   F E    D+ V+V+DIE  S 
Sbjct: 59  GENTEREGLLDTPRRVVEAFDELYQGYHQCPAEVLDRT-FGETAGYDDFVLVRDIEFTSQ 117

Query: 736 CEHHLVPFYGKVSIGYLPQGXILGLSNWPGSWKYSPAGLQVXXRLTXXIAIA 891
           CEHH++PFYGK  I Y P   ++GLS            LQ    LT  IA A
Sbjct: 118 CEHHMMPFYGKAHIAYTPVERVVGLSKLARLTDIFARRLQTQEHLTAQIAAA 169


>UniRef50_O69531 Cluster: GTP cyclohydrolase I; n=98; Bacteria|Rep:
           GTP cyclohydrolase I - Mycobacterium leprae
          Length = 205

 Score = 76.6 bits (180), Expect = 8e-13
 Identities = 46/106 (43%), Positives = 58/106 (54%), Gaps = 2/106 (1%)
 Frame = +1

Query: 580 QGLLKTPERAAKAMLFFTKGYXQSLEEVLNNAIFDEDTDEMVVVKDIEMFSMCEHHLVPF 759
           +GL  TP R A+A      G     + VLN  +FDE+ +E+V+VK+I M+S CEHHLV F
Sbjct: 42  EGLADTPARVARACRELFSGLYTDPQTVLNT-MFDEEHNELVIVKEIPMYSTCEHHLVSF 100

Query: 760 YGKVSIGYLP--QGXILGLSNWPGSWKYSPAGLQVXXRLTXXIAIA 891
           +G   IGYLP   G + GLS             QV  RLT  IA A
Sbjct: 101 HGVAHIGYLPGADGRVTGLSKIARLVDLYAKRPQVQERLTSQIADA 146


>UniRef50_A2U8J6 Cluster: GTP cyclohydrolase I; n=2; Bacillus|Rep:
           GTP cyclohydrolase I - Bacillus coagulans 36D1
          Length = 215

 Score = 76.2 bits (179), Expect = 1e-12
 Identities = 43/104 (41%), Positives = 54/104 (51%), Gaps = 1/104 (0%)
 Frame = +1

Query: 583 GLLKTPERAAKAMLFFTKGYXQSLEEVLNNAI-FDEDTDEMVVVKDIEMFSMCEHHLVPF 759
           GL +TP R  KA L +T+GY +  +  L      D D  E+V+VKDIE +S+CEHH  PF
Sbjct: 55  GLQETPYRVLKAFLEYTEGYREDPKLHLAKTFDVDHDHKELVLVKDIEFYSICEHHFAPF 114

Query: 760 YGKVSIGYLPQGXILGLSNWPGSWKYSPAGLQVXXRLTXXIAIA 891
           +G   + Y P   I GLS             QV  RLT  IA A
Sbjct: 115 FGVAHVAYFPNEKITGLSKIARMVDGYARRFQVQERLTKQIADA 158


>UniRef50_Q1IAJ6 Cluster: Putative GTP cyclohydrolase I; n=1;
           Pseudomonas entomophila L48|Rep: Putative GTP
           cyclohydrolase I - Pseudomonas entomophila (strain L48)
          Length = 202

 Score = 75.4 bits (177), Expect = 2e-12
 Identities = 42/112 (37%), Positives = 59/112 (52%), Gaps = 2/112 (1%)
 Frame = +1

Query: 562 GRTLKGQGLLKTPERAAKAMLFFTKGYXQSLEEVLNNAIFDEDTD--EMVVVKDIEMFSM 735
           G     QGL +TPER  K+M+  T GY Q    VL    F+E      ++++++I   SM
Sbjct: 24  GEDTNRQGLHETPERFLKSMVAQTVGYSQDPYRVLEK-FFEEVAGYKNLIMLQNIHFESM 82

Query: 736 CEHHLVPFYGKVSIGYLPQGXILGLSNWPGSWKYSPAGLQVXXRLTXXIAIA 891
           CEHHL P  G  ++GY+P G ++GLS            LQ+  RLT  I +A
Sbjct: 83  CEHHLAPIVGNATVGYIPNGRVVGLSKLARVVDIFAKRLQIQERLTSEIGLA 134


>UniRef50_Q68WZ4 Cluster: GTP cyclohydrolase 1; n=25; Bacteria|Rep:
           GTP cyclohydrolase 1 - Rickettsia typhi
          Length = 190

 Score = 74.1 bits (174), Expect = 4e-12
 Identities = 34/103 (33%), Positives = 58/103 (56%), Gaps = 1/103 (0%)
 Frame = +1

Query: 580 QGLLKTPERAAKAMLFFTKGYXQSLEEVLNNAIFDE-DTDEMVVVKDIEMFSMCEHHLVP 756
           +GLLKTP+R   + +    GY + ++E+LN   +D  +  +++ ++ I+  S CEHH++P
Sbjct: 27  EGLLKTPDRVINSYMEIFSGYGKDVQEILNTKFYDTYNFQDLISLEGIKFTSFCEHHILP 86

Query: 757 FYGKVSIGYLPQGXILGLSNWPGSWKYSPAGLQVXXRLTXXIA 885
           F G V I Y+P   I+G+S            LQ+  ++T  IA
Sbjct: 87  FNGTVHIAYIPDNCIIGVSKLARIVNIFSRRLQIQEKMTVQIA 129


>UniRef50_A5EFZ1 Cluster: GTP cyclohydrolase I; n=6;
           Proteobacteria|Rep: GTP cyclohydrolase I -
           Bradyrhizobium sp. (strain BTAi1 / ATCC BAA-1182)
          Length = 206

 Score = 72.9 bits (171), Expect = 1e-11
 Identities = 38/104 (36%), Positives = 60/104 (57%), Gaps = 2/104 (1%)
 Frame = +1

Query: 580 QGLLKTPERAAKAMLFFTKGYXQSLEEVLNNAIFDEDT--DEMVVVKDIEMFSMCEHHLV 753
           +GL +TP R A+A   +  GY Q+ EE L    F+E    DEMV++++I   S CEHH+ 
Sbjct: 40  EGLSETPARVARAYKSYFAGYDQNPEEYLRKT-FEETAGYDEMVLLRNIPFQSHCEHHMA 98

Query: 754 PFYGKVSIGYLPQGXILGLSNWPGSWKYSPAGLQVXXRLTXXIA 885
           P  G+  +GY+P+  ++G+S      +   + LQ+  R+T  IA
Sbjct: 99  PIIGRAWVGYVPRSRVVGISKLARVVEAYASRLQIQERMTAEIA 142


>UniRef50_Q92QB4 Cluster: GTP cyclohydrolase I; n=49;
           Proteobacteria|Rep: GTP cyclohydrolase I - Rhizobium
           meliloti (Sinorhizobium meliloti)
          Length = 204

 Score = 72.5 bits (170), Expect = 1e-11
 Identities = 44/106 (41%), Positives = 55/106 (51%), Gaps = 2/106 (1%)
 Frame = +1

Query: 580 QGLLKTPERAAKAMLFFTKGYXQSLEEVLNNAIFDEDT--DEMVVVKDIEMFSMCEHHLV 753
           +GL  TP R AKA      GY    E+VL    F+E +  D++V+ KDI  +S CEHH+V
Sbjct: 40  EGLKDTPSRVAKAYREIFGGYDLVAEDVLGRT-FEEVSGYDDIVLEKDIPFYSHCEHHMV 98

Query: 754 PFYGKVSIGYLPQGXILGLSNWPGSWKYSPAGLQVXXRLTXXIAIA 891
           P  GK  I YLP G +LGLS            LQ    +T  IA A
Sbjct: 99  PIIGKAHIAYLPNGRVLGLSKIARVVDIYARRLQTQEAMTAQIAKA 144


>UniRef50_A0RYT5 Cluster: GTP cyclohydrolase I; n=2;
           Thermoprotei|Rep: GTP cyclohydrolase I - Cenarchaeum
           symbiosum
          Length = 189

 Score = 70.1 bits (164), Expect = 7e-11
 Identities = 39/102 (38%), Positives = 55/102 (53%)
 Frame = +1

Query: 580 QGLLKTPERAAKAMLFFTKGYXQSLEEVLNNAIFDEDTDEMVVVKDIEMFSMCEHHLVPF 759
           +GL +TP R A+       GY    E  +    F ED+D  VV +DI  +S+CEHH++PF
Sbjct: 24  EGLRETPARMARMYGEIFGGYESDAELSVQ---FSEDSDA-VVARDIGFYSVCEHHMLPF 79

Query: 760 YGKVSIGYLPQGXILGLSNWPGSWKYSPAGLQVXXRLTXXIA 885
           +G + I YLP G + G+S      +     LQ+  RLT  IA
Sbjct: 80  FGSIHIAYLPDGKVFGVSKLVRLVEKYSRRLQIQERLTRNIA 121


>UniRef50_Q8T649 Cluster: GTP cyclohydrolase I; n=3; Plasmodium
           yoelii|Rep: GTP cyclohydrolase I - Plasmodium yoelii
           yoelii
          Length = 315

 Score = 69.7 bits (163), Expect = 9e-11
 Identities = 37/104 (35%), Positives = 57/104 (54%), Gaps = 2/104 (1%)
 Frame = +1

Query: 586 LLKTPERAAKAMLFFTKGYXQSLEEVLNNAIFDED--TDEMVVVKDIEMFSMCEHHLVPF 759
           L +T  R AKA L+ T+GY  S++ V+  +I+      + ++ +KDI ++S+C+HHL+PF
Sbjct: 142 LKRTNNRFAKAFLYLTEGYKMSVKNVIKKSIYKRKYKNNTLIKIKDIHVYSLCKHHLLPF 201

Query: 760 YGKVSIGYLPQGXILGLSNWPGSWKYSPAGLQVXXRLTXXIAIA 891
            G   I Y P   I+GLS +          LQ+   LT  I  A
Sbjct: 202 EGLCDIEYNPDKYIMGLSKFSRITDIYARRLQLQEDLTNDICNA 245


>UniRef50_UPI0000DADB56 Cluster: hypothetical protein
           RcanM_01000666; n=1; Rickettsia canadensis str.
           McKiel|Rep: hypothetical protein RcanM_01000666 -
           Rickettsia canadensis str. McKiel
          Length = 222

 Score = 69.3 bits (162), Expect = 1e-10
 Identities = 33/103 (32%), Positives = 54/103 (52%), Gaps = 1/103 (0%)
 Frame = +1

Query: 580 QGLLKTPERAAKAMLFFTKGYXQSLEEVLNNAIFDE-DTDEMVVVKDIEMFSMCEHHLVP 756
           +GLLKTP+R   + +    GY + + E+L+   +D  +  + + +  I   S CEHH++P
Sbjct: 59  EGLLKTPDRVINSYMEIFSGYEKDVAEILSTKFYDTCNFQDFISLDGIRFTSFCEHHMLP 118

Query: 757 FYGKVSIGYLPQGXILGLSNWPGSWKYSPAGLQVXXRLTXXIA 885
           F G V I Y+P   I+G+S            LQ+  ++T  IA
Sbjct: 119 FNGTVHISYIPDNCIIGISKLARIVNVFARRLQIQEKMTVQIA 161


>UniRef50_Q88ST4 Cluster: GTP cyclohydrolase I; n=11;
           Lactobacillales|Rep: GTP cyclohydrolase I -
           Lactobacillus plantarum
          Length = 189

 Score = 69.3 bits (162), Expect = 1e-10
 Identities = 44/105 (41%), Positives = 59/105 (56%), Gaps = 4/105 (3%)
 Frame = +1

Query: 583 GLLKTPERAAK--AMLFFTKGYXQSLEEVLNNAIFD-EDTDEMVVVKDIEMFSMCEHHLV 753
           GL++TP R A+  A +F TK    +     N  +F  E   EMV++KDI  +SMCEHHL+
Sbjct: 29  GLVETPARVARMYAEVFATK----TAAPFDNYKLFKVEHPTEMVLLKDIPFYSMCEHHLL 84

Query: 754 PFYGKVSIGYLPQ-GXILGLSNWPGSWKYSPAGLQVXXRLTXXIA 885
           PF+G V + Y+PQ   ++GLS  P    Y      V  RLT  IA
Sbjct: 85  PFFGTVQVAYVPQHEQVIGLSKIPRLIDYCSQQPNVQERLTVSIA 129


>UniRef50_Q5HBC9 Cluster: GTP cyclohydrolase I; n=4; canis
           group|Rep: GTP cyclohydrolase I - Ehrlichia ruminantium
           (strain Welgevonden)
          Length = 190

 Score = 68.9 bits (161), Expect = 2e-10
 Identities = 40/102 (39%), Positives = 52/102 (50%), Gaps = 1/102 (0%)
 Frame = +1

Query: 583 GLLKTPERAAKAMLFFTKGYXQSLEEVLNNAIF-DEDTDEMVVVKDIEMFSMCEHHLVPF 759
           GL+ TP R   A   F  GY Q +  V+  ++  +E  D M+  KDI   S CEHH++P 
Sbjct: 31  GLIGTPRRMLNAYKKFFIGY-QDISLVIGGSVLPNEGYDSMITFKDIGFVSYCEHHIIPM 89

Query: 760 YGKVSIGYLPQGXILGLSNWPGSWKYSPAGLQVXXRLTXXIA 885
            GKV+IGY+P   I  +        Y    LQV  RLT  IA
Sbjct: 90  RGKVNIGYVPDKVIFTIGQVIRLVNYFSKRLQVQERLTVDIA 131


>UniRef50_Q9PC02 Cluster: GTP cyclohydrolase I; n=16; Bacteria|Rep:
           GTP cyclohydrolase I - Xylella fastidiosa
          Length = 203

 Score = 68.9 bits (161), Expect = 2e-10
 Identities = 37/104 (35%), Positives = 57/104 (54%), Gaps = 2/104 (1%)
 Frame = +1

Query: 580 QGLLKTPERAAKAMLFFTKGYXQSLEEVLNNAIFDEDT--DEMVVVKDIEMFSMCEHHLV 753
           +GLL TP R  +A   +  GY +   + L    F+E +  DE++V+++I   S CEHH+ 
Sbjct: 34  EGLLDTPRRVVEAYGDWFSGYREDPHDYLQRT-FEEISGYDELIVLRNITYESHCEHHMA 92

Query: 754 PFYGKVSIGYLPQGXILGLSNWPGSWKYSPAGLQVXXRLTXXIA 885
           P  GKV IGYLP G ++G+S      +      Q+  ++T  IA
Sbjct: 93  PIIGKVHIGYLPNGKVVGISKLARVVESYARRFQIQEKMTAQIA 136


>UniRef50_A5Z385 Cluster: Putative uncharacterized protein; n=1;
           Eubacterium ventriosum ATCC 27560|Rep: Putative
           uncharacterized protein - Eubacterium ventriosum ATCC
           27560
          Length = 151

 Score = 68.5 bits (160), Expect = 2e-10
 Identities = 34/85 (40%), Positives = 51/85 (60%)
 Frame = +1

Query: 637 GYXQSLEEVLNNAIFDEDTDEMVVVKDIEMFSMCEHHLVPFYGKVSIGYLPQGXILGLSN 816
           G  +S +E L+   F  D + +V+ KDI  +S CEHHL+PFYGKV I Y+P G ++G+S 
Sbjct: 8   GMNRSPKEHLSKT-FTCDNENVVIEKDITFYSTCEHHLMPFYGKVHIAYIPNGKVVGISK 66

Query: 817 WPGSWKYSPAGLQVXXRLTXXIAIA 891
              + +     LQ+  ++T  IA A
Sbjct: 67  LARTVEVYARRLQIQEQMTNQIAKA 91


>UniRef50_A2BL58 Cluster: GTP cyclohydrolase I; n=2;
           Thermoprotei|Rep: GTP cyclohydrolase I - Hyperthermus
           butylicus (strain DSM 5456 / JCM 9403)
          Length = 193

 Score = 68.1 bits (159), Expect = 3e-10
 Identities = 41/110 (37%), Positives = 57/110 (51%)
 Frame = +1

Query: 556 AWGRTLKGQGLLKTPERAAKAMLFFTKGYXQSLEEVLNNAIFDEDTDEMVVVKDIEMFSM 735
           A G   + +GL +TP R A       +GY  + E       F E TD +VVV  I  +S+
Sbjct: 18  AIGEDPEREGLRETPRRVADMFEELLEGYDFTEEYTW----FTEATD-LVVVSGIRFYSL 72

Query: 736 CEHHLVPFYGKVSIGYLPQGXILGLSNWPGSWKYSPAGLQVXXRLTXXIA 885
           CEHHL+PF+G   + YLP+G ++GLS            LQ+  R+T  IA
Sbjct: 73  CEHHLLPFFGVAHVAYLPRGKVIGLSKIVRIVNKYSRRLQIQERMTKQIA 122


>UniRef50_Q6SIF0 Cluster: GTP cyclohydrolase I; n=1; Plasmodium
           knowlesi|Rep: GTP cyclohydrolase I - Plasmodium knowlesi
          Length = 451

 Score = 67.7 bits (158), Expect = 4e-10
 Identities = 34/104 (32%), Positives = 58/104 (55%), Gaps = 2/104 (1%)
 Frame = +1

Query: 586 LLKTPERAAKAMLFFTKGYXQSLEEVLNNAIFDED--TDEMVVVKDIEMFSMCEHHLVPF 759
           L KT  R +   L+ TKGY  S+E+V+  +++  +   + ++ +  I ++S+C+HHL+PF
Sbjct: 275 LKKTGRRFSDTFLYLTKGYHMSVEKVIKKSLYKRNYKNNSVIKISGIHIYSLCKHHLLPF 334

Query: 760 YGKVSIGYLPQGXILGLSNWPGSWKYSPAGLQVXXRLTXXIAIA 891
            G+ +I Y+P   I+GLS +          LQ+   LT  I  A
Sbjct: 335 EGECTIEYIPNKYIMGLSKFSRVIDIFARRLQLQEDLTNDICNA 378


>UniRef50_Q01A10 Cluster: GTP cyclohydrolase I; n=2;
           Ostreococcus|Rep: GTP cyclohydrolase I - Ostreococcus
           tauri
          Length = 504

 Score = 66.1 bits (154), Expect = 1e-09
 Identities = 38/104 (36%), Positives = 57/104 (54%), Gaps = 18/104 (17%)
 Frame = +1

Query: 556 AWGRTLKGQGLLKTPERAAKAMLFFTKGYXQSLEEVLNNAIFDED--------------- 690
           A G  ++ +GL+ TP R AKA+ F  +GY       L  A+F+ED               
Sbjct: 67  AMGEDVEREGLMDTPARVAKALAFAMRGYDACPTAALGTALFNEDGLARASSASTKEDVE 126

Query: 691 --TDEMVVVKDIEMFSMCEHHLVPFYGKVSIGYLPQ-GXILGLS 813
             T+++V+V+DI +FS C    +PFYG + +GY P+ G I+GLS
Sbjct: 127 LGTNDVVLVRDIPVFSTCARTFMPFYGVIHVGYAPRAGVIVGLS 170



 Score = 47.2 bits (107), Expect = 6e-04
 Identities = 27/70 (38%), Positives = 35/70 (50%), Gaps = 2/70 (2%)
 Frame = +1

Query: 682 DEDTDEMVVVKDIEMFSMCEHHLVPFYGKVSIGYL--PQGXILGLSNWPGSWKYSPAGLQ 855
           DE  D + V +D+ M ++CEHHL+PF+G VS  Y+  P    L               LQ
Sbjct: 371 DEIEDGVCVTRDLHMSTVCEHHLLPFHGTVSAAYMTGPGAQPLSRDTLQAIVSRHSRRLQ 430

Query: 856 VXXRLTXXIA 885
           V  RLT  IA
Sbjct: 431 VQERLTRDIA 440


>UniRef50_Q8S3C2 Cluster: GTP cyclohydrolase I; n=7; core
           eudicotyledons|Rep: GTP cyclohydrolase I - Arabidopsis
           thaliana (Mouse-ear cress)
          Length = 466

 Score = 64.9 bits (151), Expect = 3e-09
 Identities = 43/116 (37%), Positives = 63/116 (54%), Gaps = 12/116 (10%)
 Frame = +1

Query: 580 QGLLKTPERAAKAMLFFTKGYXQSLEEVLNNAIFDE-DTDE----------MVVVKDIEM 726
           +G+ KTP R AKA+   T+GY Q +++ + +A+F E   DE          +VVV+D++ 
Sbjct: 53  EGIKKTPFRVAKALREGTRGYKQKVKDYVQSALFPEAGLDEGVGQAGGVGGLVVVRDLDH 112

Query: 727 FSMCEHHLVPFYGKVSIGYLPQG-XILGLSNWPGSWKYSPAGLQVXXRLTXXIAIA 891
           +S CE  L+PF+ K  IGY+P G  +LGLS +          LQ   RL   I  A
Sbjct: 113 YSYCESCLLPFHVKCHIGYVPSGQRVLGLSKFSRVTDVFAKRLQDPQRLADDICSA 168



 Score = 47.2 bits (107), Expect = 6e-04
 Identities = 27/68 (39%), Positives = 37/68 (54%), Gaps = 2/68 (2%)
 Frame = +1

Query: 586 LLKTPERAAKAMLFFTKGYXQSLEEVLNNAIFDEDTDEMVVVKDIEM--FSMCEHHLVPF 759
           L+ TP R  K ML F +   +      N A  + +  E  +  ++ M  +SMCEHHL+PF
Sbjct: 290 LIATPTRFLKWMLNFQRTNLEMKLNSFNPAKVNGEVKEKRLHCELNMPFWSMCEHHLLPF 349

Query: 760 YGKVSIGY 783
           YG V IGY
Sbjct: 350 YGVVHIGY 357


>UniRef50_A4CGT7 Cluster: GTP cyclohydrolase I; n=1; Robiginitalea
           biformata HTCC2501|Rep: GTP cyclohydrolase I -
           Robiginitalea biformata HTCC2501
          Length = 176

 Score = 64.5 bits (150), Expect = 4e-09
 Identities = 42/113 (37%), Positives = 57/113 (50%), Gaps = 3/113 (2%)
 Frame = +1

Query: 556 AWGRTLKGQGLLKTPERAAKAMLFFT-KGYXQSLEEVLNNAIFDE--DTDEMVVVKDIEM 726
           A G  L    L  TP R A+  +  T +G   S +     + F++   T EM+VV DI +
Sbjct: 3   ALGMDLSDTSLADTPMRVARMYVNETFRGL--SAKNFPRISFFEKAPGTPEMIVVNDITL 60

Query: 727 FSMCEHHLVPFYGKVSIGYLPQGXILGLSNWPGSWKYSPAGLQVXXRLTXXIA 885
           +S CEHH VPF+GKV + Y+P   +LGLS       Y      +  RLT  IA
Sbjct: 61  YSYCEHHFVPFFGKVHVAYIPGDRLLGLSKVNRVVDYLSRKPHLQERLTREIA 113


>UniRef50_A5K040 Cluster: GTP cyclohydrolase I, putative; n=1;
           Plasmodium vivax|Rep: GTP cyclohydrolase I, putative -
           Plasmodium vivax
          Length = 423

 Score = 64.1 bits (149), Expect = 5e-09
 Identities = 32/104 (30%), Positives = 55/104 (52%), Gaps = 2/104 (1%)
 Frame = +1

Query: 586 LLKTPERAAKAMLFFTKGYXQSLEEVLNNAIFDED--TDEMVVVKDIEMFSMCEHHLVPF 759
           L +T +R     L+ TKGY  ++ +V+  +++      D  + +  I ++S+C+HHL+PF
Sbjct: 245 LKRTSKRFTDTFLYLTKGYHMNVGKVIKKSLYKRKYKNDSRIKISGIHIYSLCKHHLLPF 304

Query: 760 YGKVSIGYLPQGXILGLSNWPGSWKYSPAGLQVXXRLTXXIAIA 891
            G+ SI Y+P   ++GLS +          LQ+   LT  I  A
Sbjct: 305 EGECSIEYVPNRYVMGLSKFSRVINIFARRLQLQEDLTNDICNA 348


>UniRef50_O97071 Cluster: GTP cyclohydrolase I; n=6; Plasmodium|Rep:
           GTP cyclohydrolase I - Plasmodium falciparum
          Length = 389

 Score = 62.5 bits (145), Expect = 1e-08
 Identities = 32/104 (30%), Positives = 54/104 (51%), Gaps = 2/104 (1%)
 Frame = +1

Query: 586 LLKTPERAAKAMLFFTKGYXQSLEEVLNNAIFDE--DTDEMVVVKDIEMFSMCEHHLVPF 759
           L +T  R A+  L+ T GY   +E+++  +++      + ++ V  I ++S+C+HHL+PF
Sbjct: 225 LKRTNRRYAETFLYLTNGYNLDIEQIIKRSLYKRMYKNNSIIKVTGIHIYSLCKHHLLPF 284

Query: 760 YGKVSIGYLPQGXILGLSNWPGSWKYSPAGLQVXXRLTXXIAIA 891
            G   I Y+P   I+GLS +          LQ+   LT  I  A
Sbjct: 285 EGTCDIEYIPNKYIIGLSKFSRIVDVFSRRLQLQEDLTNDICNA 328


>UniRef50_Q2GK14 Cluster: GTP cyclohydrolase I; n=2; Anaplasma
           phagocytophilum HZ|Rep: GTP cyclohydrolase I - Anaplasma
           phagocytophilum (strain HZ)
          Length = 202

 Score = 61.7 bits (143), Expect = 2e-08
 Identities = 37/102 (36%), Positives = 49/102 (48%)
 Frame = +1

Query: 580 QGLLKTPERAAKAMLFFTKGYXQSLEEVLNNAIFDEDTDEMVVVKDIEMFSMCEHHLVPF 759
           +GLLKTP R          GY   L    +   +D  + EMV+VK+I   S CEHHL P 
Sbjct: 35  EGLLKTPRRVLDYYKKSCSGYAPELLSHYSILPYDGSSSEMVLVKNIGFSSNCEHHLSPI 94

Query: 760 YGKVSIGYLPQGXILGLSNWPGSWKYSPAGLQVXXRLTXXIA 885
            G   I Y+P+  ILG+ +           LQ+  RLT  +A
Sbjct: 95  CGVAHIAYMPKEKILGIGSIAHIVGCFSKRLQLQERLTNQVA 136


>UniRef50_Q0CVT9 Cluster: GTP cyclohydrolase I; n=1; Aspergillus
           terreus NIH2624|Rep: GTP cyclohydrolase I - Aspergillus
           terreus (strain NIH 2624)
          Length = 216

 Score = 61.7 bits (143), Expect = 2e-08
 Identities = 42/104 (40%), Positives = 54/104 (51%)
 Frame = +1

Query: 580 QGLLKTPERAAKAMLFFTKGYXQSLEEVLNNAIFDEDTDEMVVVKDIEMFSMCEHHLVPF 759
           +GL  TPER AKAML+FTKGY +++ +  N AIF ED   ++V                 
Sbjct: 74  EGLRATPERYAKAMLYFTKGYSENIFDRANGAIFHEDYKGLIV----------------- 116

Query: 760 YGKVSIGYLPQGXILGLSNWPGSWKYSPAGLQVXXRLTXXIAIA 891
              + IGY+P G ILGLS      +     LQV  RLT  +AIA
Sbjct: 117 ---MHIGYIPDGRILGLSKMAHLAEVFSRRLQVQERLTEQVAIA 157


>UniRef50_Q97D54 Cluster: GTP cyclohydrolase I; n=7;
           Clostridium|Rep: GTP cyclohydrolase I - Clostridium
           acetobutylicum
          Length = 195

 Score = 61.3 bits (142), Expect = 3e-08
 Identities = 35/86 (40%), Positives = 50/86 (58%), Gaps = 8/86 (9%)
 Frame = +1

Query: 580 QGLLKTPERAAKAMLFFTKGYXQSLEEVLN--NAIFDEDT-----DEMVVVKDIEMFSMC 738
           +GL +TP+R AK      KG   S +++    N  F+ED      D +V+VKDIE+FS C
Sbjct: 26  EGLKETPKRVAKMYEEVFKGMEYSNDDIAEMFNKTFEEDLKESEEDNIVLVKDIEIFSHC 85

Query: 739 EHHLVPFYG-KVSIGYLPQGXILGLS 813
           EHHL   Y   V++ Y+P   ++GLS
Sbjct: 86  EHHLTLMYNMTVAVAYIPNKRLIGLS 111


>UniRef50_Q2JC68 Cluster: GTP cyclohydrolase I; n=1; Frankia sp.
           CcI3|Rep: GTP cyclohydrolase I - Frankia sp. (strain
           CcI3)
          Length = 192

 Score = 60.1 bits (139), Expect = 8e-08
 Identities = 39/103 (37%), Positives = 55/103 (53%)
 Frame = +1

Query: 583 GLLKTPERAAKAMLFFTKGYXQSLEEVLNNAIFDEDTDEMVVVKDIEMFSMCEHHLVPFY 762
           GL +TP R A+    F  G+     E    A    +  ++V V DI ++S+CEHHL+PF+
Sbjct: 42  GLRETPARYARWWREFV-GFDPGNTET---AFEQVNHGQLVQVNDIRVWSLCEHHLLPFW 97

Query: 763 GKVSIGYLPQGXILGLSNWPGSWKYSPAGLQVXXRLTXXIAIA 891
             +SI YL +  +LGLS +     +    LQV  RLT  IA A
Sbjct: 98  CDISIAYLAKDKLLGLSKFARIAHHHAHRLQVQERLTGAIADA 140


>UniRef50_Q8RH43 Cluster: GTP cyclohydrolase I; n=3; Fusobacterium
           nucleatum|Rep: GTP cyclohydrolase I - Fusobacterium
           nucleatum subsp. nucleatum
          Length = 187

 Score = 58.8 bits (136), Expect = 2e-07
 Identities = 33/100 (33%), Positives = 53/100 (53%)
 Frame = +1

Query: 586 LLKTPERAAKAMLFFTKGYXQSLEEVLNNAIFDEDTDEMVVVKDIEMFSMCEHHLVPFYG 765
           L  TP+R A +      G     +EVL    F+ +++E+++ K+++ +SMCEHH +PF+G
Sbjct: 30  LKDTPKRIADSYKEIFYGIDIDPKEVLTKT-FEVNSNELIMEKNMDFYSMCEHHFLPFFG 88

Query: 766 KVSIGYLPQGXILGLSNWPGSWKYSPAGLQVXXRLTXXIA 885
            V I Y+P   I G  +     +      Q+  RLT  IA
Sbjct: 89  TVCIAYVPNKKIFGFGDILKLIEILSRRPQLQERLTEEIA 128


>UniRef50_A1SM21 Cluster: GTP cyclohydrolase I precursor; n=7;
           Actinomycetales|Rep: GTP cyclohydrolase I precursor -
           Nocardioides sp. (strain BAA-499 / JS614)
          Length = 219

 Score = 58.4 bits (135), Expect = 2e-07
 Identities = 37/110 (33%), Positives = 53/110 (48%)
 Frame = +1

Query: 556 AWGRTLKGQGLLKTPERAAKAMLFFTKGYXQSLEEVLNNAIFDEDTDEMVVVKDIEMFSM 735
           A G  ++   +++TP R   A      G    L    N     E  DE+V+V +I + S+
Sbjct: 50  ALGLDIETDEMVETPRRLVAAYHELLTGPDVDLTTFPNT----EGYDELVLVANIPVRSV 105

Query: 736 CEHHLVPFYGKVSIGYLPQGXILGLSNWPGSWKYSPAGLQVXXRLTXXIA 885
           CEHH++PF G   +GYLP   ILGLS +    +      Q   RLT  +A
Sbjct: 106 CEHHMLPFVGVAHVGYLPDERILGLSKFARLVELVARRPQTQERLTTEVA 155


>UniRef50_A4QTK3 Cluster: Putative uncharacterized protein; n=1;
           Magnaporthe grisea|Rep: Putative uncharacterized protein
           - Magnaporthe grisea (Rice blast fungus) (Pyricularia
           grisea)
          Length = 216

 Score = 58.4 bits (135), Expect = 2e-07
 Identities = 37/107 (34%), Positives = 56/107 (52%)
 Frame = +1

Query: 580 QGLLKTPERAAKAMLFFTKGYXQSLEEVLNNAIFDEDTDEMVVVKDIEMFSMCEHHLVPF 759
           +GL +TP R A+A+ FFT+GY +++ EV N+AIF  D+ E+V+                 
Sbjct: 71  EGLAETPNRYAEALQFFTQGYSKNIHEVSNDAIFSIDSRELVI----------------- 113

Query: 760 YGKVSIGYLPQGXILGLSNWPGSWKYSPAGLQVXXRLTXXIAIAXTQ 900
              + IGY+P G +LGLS  P   +     LQ+  RLT  +  A  +
Sbjct: 114 ---MHIGYVPNGRVLGLSKLPRIAEVYARRLQIQERLTKQVGEAINE 157


>UniRef50_Q8ZWW5 Cluster: GTP cyclohydrolase I; n=4;
           Pyrobaculum|Rep: GTP cyclohydrolase I - Pyrobaculum
           aerophilum
          Length = 187

 Score = 57.6 bits (133), Expect = 4e-07
 Identities = 35/108 (32%), Positives = 56/108 (51%)
 Frame = +1

Query: 562 GRTLKGQGLLKTPERAAKAMLFFTKGYXQSLEEVLNNAIFDEDTDEMVVVKDIEMFSMCE 741
           G  L   G+L TP+R  KAM   T+G  +   EV+   +  +     VV+++I   S+CE
Sbjct: 23  GEDLTKPGVLNTPKRFVKAMEELTRGLREPPPEVVFFPLEYDVELGPVVIENIGAVSLCE 82

Query: 742 HHLVPFYGKVSIGYLPQGXILGLSNWPGSWKYSPAGLQVXXRLTXXIA 885
           HHL+P   ++S+ Y+P   + GLS      K++ A   +  R T  +A
Sbjct: 83  HHLLPILLRISVAYVPGDGVPGLSKVIRLVKWAAARPIMQERFTEWLA 130


>UniRef50_Q971G9 Cluster: GTP cyclohydrolase I; n=4;
           Sulfolobaceae|Rep: GTP cyclohydrolase I - Sulfolobus
           tokodaii
          Length = 215

 Score = 57.2 bits (132), Expect = 5e-07
 Identities = 36/110 (32%), Positives = 56/110 (50%), Gaps = 6/110 (5%)
 Frame = +1

Query: 580 QGLLKTPERAAKAMLFFTKGYXQSLEEV----LNNAIFDEDTDEMVVVKDIEMFSMCEHH 747
           +GL +TP R A+A+L  T G      ++    L+     E  D++++VK+I   S+CEHH
Sbjct: 40  EGLRETPLRVARALLEMTSGLRTPQPQIKTFNLSEDGISEVEDQIILVKNIGFSSLCEHH 99

Query: 748 LVPFYGKVSIGYL--PQGXILGLSNWPGSWKYSPAGLQVXXRLTXXIAIA 891
           L+P  GKV + Y+   +  + G S       Y  +  Q+  RL   IA A
Sbjct: 100 LLPIIGKVHVAYIVGQERKVAGFSKIIRIVNYYASRPQIQERLVQQIADA 149


>UniRef50_Q6MK87 Cluster: FolE protein; n=1; Bdellovibrio
           bacteriovorus|Rep: FolE protein - Bdellovibrio
           bacteriovorus
          Length = 242

 Score = 56.8 bits (131), Expect = 7e-07
 Identities = 36/109 (33%), Positives = 53/109 (48%), Gaps = 1/109 (0%)
 Frame = +1

Query: 562 GRTLKGQGLLKTPERAAKAMLFFTKGYXQSLEEVLNNAIFDE-DTDEMVVVKDIEMFSMC 738
           G  LK   L +TP+R AK  +    G     +      I ++ + D+M+VV+ I   S C
Sbjct: 72  GLDLKDDSLRETPKRVAKMYVNEVFGGLDPKKFPKMTVIDNKMNYDQMIVVQSIGCLSFC 131

Query: 739 EHHLVPFYGKVSIGYLPQGXILGLSNWPGSWKYSPAGLQVXXRLTXXIA 885
           EHH +P  G  ++ Y+P   ++GLS      +Y     QV  RLT  IA
Sbjct: 132 EHHFLPIDGFATVAYIPNKKVIGLSKINRIVQYFSRRPQVQERLTKQIA 180


>UniRef50_UPI00015BB290 Cluster: GTP cyclohydrolase; n=1; Ignicoccus
           hospitalis KIN4/I|Rep: GTP cyclohydrolase - Ignicoccus
           hospitalis KIN4/I
          Length = 186

 Score = 56.0 bits (129), Expect = 1e-06
 Identities = 34/103 (33%), Positives = 53/103 (51%), Gaps = 2/103 (1%)
 Frame = +1

Query: 583 GLLKTPERAAKAMLFFTKGYXQSLEEVLN-NAIFDEDTDEMVVVKDIEMFSMCEHHLVPF 759
           GL +TPER  +A+    KG      E+      +    ++++VVK++   S+CEHHL+P 
Sbjct: 25  GLSETPERYVRALRELFKGLETPKPELKTFKTEYLLGENDLIVVKNVSFSSLCEHHLLPI 84

Query: 760 YGKVSIGYLP-QGXILGLSNWPGSWKYSPAGLQVXXRLTXXIA 885
            G+ SI Y P +  ++GLS  P   K+      +  R T  IA
Sbjct: 85  LGRASIVYHPKRDEVIGLSKIPRIVKWLAKRPMLQERFTAMIA 127


>UniRef50_Q8ZG15 Cluster: GTP cyclohydrolase I; n=129; root|Rep: GTP
           cyclohydrolase I - Yersinia pestis
          Length = 220

 Score = 55.6 bits (128), Expect = 2e-06
 Identities = 27/66 (40%), Positives = 38/66 (57%)
 Frame = +1

Query: 694 DEMVVVKDIEMFSMCEHHLVPFYGKVSIGYLPQGXILGLSNWPGSWKYSPAGLQVXXRLT 873
           DEMV V+DI + S CEHH V   GK ++ Y+P+  ++GLS      ++     QV  RLT
Sbjct: 95  DEMVTVRDITLTSTCEHHFVTIDGKATVAYIPKDSVIGLSKINRIVQFFAQRPQVQERLT 154

Query: 874 XXIAIA 891
             I +A
Sbjct: 155 QQILLA 160


>UniRef50_Q6ME26 Cluster: Probable GTP cyclohydrolase I; n=1;
           Candidatus Protochlamydia amoebophila UWE25|Rep:
           Probable GTP cyclohydrolase I - Protochlamydia
           amoebophila (strain UWE25)
          Length = 224

 Score = 55.2 bits (127), Expect = 2e-06
 Identities = 36/109 (33%), Positives = 53/109 (48%), Gaps = 4/109 (3%)
 Frame = +1

Query: 571 LKGQGLLKTPERAAKAML--FFTKGYXQSLEEV--LNNAIFDEDTDEMVVVKDIEMFSMC 738
           ++ + L +TPER AK  +   F+    ++  E+    + I  E    MV VK +   S C
Sbjct: 53  VEDESLARTPERVAKMYVNEIFSGLDEENFPEISFFKDEIHHEHKANMVFVK-VGFTSFC 111

Query: 739 EHHLVPFYGKVSIGYLPQGXILGLSNWPGSWKYSPAGLQVXXRLTXXIA 885
           EHH VP  G   + Y+P   ++GLS  P   +Y     Q+  RLT  IA
Sbjct: 112 EHHFVPMSGFAYVAYIPTNQLIGLSKIPRLVRYFAKRPQLQERLTAQIA 160


>UniRef50_UPI000038E307 Cluster: hypothetical protein Faci_03001748;
           n=1; Ferroplasma acidarmanus fer1|Rep: hypothetical
           protein Faci_03001748 - Ferroplasma acidarmanus fer1
          Length = 191

 Score = 54.4 bits (125), Expect = 4e-06
 Identities = 22/42 (52%), Positives = 32/42 (76%), Gaps = 2/42 (4%)
 Frame = +1

Query: 694 DEMVVVKDIEMFSMCEHHLVPFYGKVSIGYLPQ--GXILGLS 813
           + MV+VK+I  +SMC HHL+PF+G ++I YLP+  G I G+S
Sbjct: 63  ESMVIVKNISFYSMCSHHLLPFFGNINIAYLPRPAGYIAGVS 104


>UniRef50_Q5PAR5 Cluster: GTP cyclohydrolase; n=1; Anaplasma
           marginale str. St. Maries|Rep: GTP cyclohydrolase -
           Anaplasma marginale (strain St. Maries)
          Length = 198

 Score = 54.0 bits (124), Expect = 5e-06
 Identities = 30/103 (29%), Positives = 49/103 (47%), Gaps = 1/103 (0%)
 Frame = +1

Query: 580 QGLLKTPERAAKAMLFFTKGYXQSLEEVLNNAIF-DEDTDEMVVVKDIEMFSMCEHHLVP 756
           +GL  T  R   A     +GY         N++F +E   +M++++ +   S CEHH+ P
Sbjct: 32  EGLSLTAGRVLNAYKESFQGYALESSHDFRNSVFANEGYSDMILLRGVNFSSTCEHHMSP 91

Query: 757 FYGKVSIGYLPQGXILGLSNWPGSWKYSPAGLQVXXRLTXXIA 885
             G V+I Y+P+  ++G+             LQV  R+T  IA
Sbjct: 92  MAGVVNISYIPKATVIGVGTVVRVVDIFAKRLQVQERMTVQIA 134


>UniRef50_Q5V5Y0 Cluster: GTP cyclohydrolase I; n=1; Haloarcula
           marismortui|Rep: GTP cyclohydrolase I - Haloarcula
           marismortui (Halobacterium marismortui)
          Length = 210

 Score = 53.6 bits (123), Expect = 7e-06
 Identities = 35/111 (31%), Positives = 50/111 (45%), Gaps = 1/111 (0%)
 Frame = +1

Query: 556 AWGRTLKGQGLLKTPERAAKAML-FFTKGYXQSLEEVLNNAIFDEDTDEMVVVKDIEMFS 732
           A GR     GL  T  R    M    T+G     + ++    FD +TD ++V   I + S
Sbjct: 37  AAGRDPDSAGLSDTWSRRVPDMFETLTEGARSESKPIMRT--FDAETDGLIVKTGIPLHS 94

Query: 733 MCEHHLVPFYGKVSIGYLPQGXILGLSNWPGSWKYSPAGLQVXXRLTXXIA 885
           MCEHH++PF G   + Y P   ++GLS      ++    L     LT  IA
Sbjct: 95  MCEHHMLPFRGVAHVAYRPGDQMVGLSKLIRYVRWQSRQLTTQETLTRDIA 145


>UniRef50_Q23AG3 Cluster: GTP cyclohydrolase I family protein; n=1;
           Tetrahymena thermophila SB210|Rep: GTP cyclohydrolase I
           family protein - Tetrahymena thermophila SB210
          Length = 223

 Score = 51.2 bits (117), Expect = 3e-05
 Identities = 24/66 (36%), Positives = 38/66 (57%)
 Frame = +1

Query: 694 DEMVVVKDIEMFSMCEHHLVPFYGKVSIGYLPQGXILGLSNWPGSWKYSPAGLQVXXRLT 873
           +EMV ++DI + + CEHH + F G  ++ Y+P+  +LGLS      ++     QV  RLT
Sbjct: 99  NEMVQIQDIALTTTCEHHFITFDGFATVAYIPKDKVLGLSKINRLVRFFSKRPQVQERLT 158

Query: 874 XXIAIA 891
             I +A
Sbjct: 159 KQILVA 164


>UniRef50_Q1FI35 Cluster: GTP cyclohydrolase I; n=1; Clostridium
           phytofermentans ISDg|Rep: GTP cyclohydrolase I -
           Clostridium phytofermentans ISDg
          Length = 194

 Score = 50.8 bits (116), Expect = 5e-05
 Identities = 29/86 (33%), Positives = 47/86 (54%), Gaps = 8/86 (9%)
 Frame = +1

Query: 580 QGLLKTPERAAKAMLFFTKGYXQSLEEVLN--NAIFDEDTDE-----MVVVKDIEMFSMC 738
           +GL+ TP+R A        G   + ++++   N  F+ED +      +V +KDIE FS C
Sbjct: 26  EGLIDTPKRVANMYEEVFLGIQYTNDDIVTMFNKCFEEDQNTFLANGIVWIKDIECFSFC 85

Query: 739 EHHLVPFYG-KVSIGYLPQGXILGLS 813
           EHH+   Y   ++IGY P   ++G+S
Sbjct: 86  EHHMTLIYDMHITIGYKPLHKVIGIS 111


>UniRef50_A3J0S0 Cluster: GTP cyclohydrolase I; n=28;
           Bacteroidetes|Rep: GTP cyclohydrolase I - Flavobacteria
           bacterium BAL38
          Length = 249

 Score = 49.6 bits (113), Expect = 1e-04
 Identities = 36/111 (32%), Positives = 47/111 (42%), Gaps = 4/111 (3%)
 Frame = +1

Query: 562 GRTLKGQGLLKTPERAAKAMLFFTKGYXQSLEEVLNN--AIFDEDT--DEMVVVKDIEMF 729
           G  L    L  TP R AK    F +     L        ++FD     D+M+V  +I   
Sbjct: 81  GLDLTDDSLQGTPHRVAK---MFVQEIFSGLNPANKPKISVFDNSYQYDKMLVEANISFN 137

Query: 730 SMCEHHLVPFYGKVSIGYLPQGXILGLSNWPGSWKYSPAGLQVXXRLTXXI 882
           S CEHH +P  GK  IGY+  G ++GLS       Y     QV  R+   I
Sbjct: 138 STCEHHFLPIVGKAHIGYVSSGKVIGLSKLNRIVDYYARRPQVQERMIMQI 188


>UniRef50_Q1Q0A8 Cluster: Strongly similar to GTP cyclohydrolase I;
           n=1; Candidatus Kuenenia stuttgartiensis|Rep: Strongly
           similar to GTP cyclohydrolase I - Candidatus Kuenenia
           stuttgartiensis
          Length = 212

 Score = 48.8 bits (111), Expect = 2e-04
 Identities = 28/88 (31%), Positives = 42/88 (47%), Gaps = 4/88 (4%)
 Frame = +1

Query: 562 GRTLKGQGLLKTPERAAKAMLFFTKGYX--QSLEEVLNNAIFDEDTDEM--VVVKDIEMF 729
           G  L      +TP R   A++  T+GY     L +V            +  ++   I  F
Sbjct: 40  GLNLNTAATKETPHRFINALIESTEGYDGDPKLVKVFETECRGGPDCRLSQIIEGPIRFF 99

Query: 730 SMCEHHLVPFYGKVSIGYLPQGXILGLS 813
           ++CEHH +PFYG V +GY+    I+GLS
Sbjct: 100 ALCEHHCLPFYGVVYVGYISHEHIIGLS 127


>UniRef50_Q08SR8 Cluster: GTP cyclohydrolase I 2; n=2;
           Cystobacterineae|Rep: GTP cyclohydrolase I 2 -
           Stigmatella aurantiaca DW4/3-1
          Length = 153

 Score = 48.8 bits (111), Expect = 2e-04
 Identities = 23/65 (35%), Positives = 34/65 (52%), Gaps = 2/65 (3%)
 Frame = +1

Query: 619 MLFFTKGYXQSLEEVLNNAIF--DEDTDEMVVVKDIEMFSMCEHHLVPFYGKVSIGYLPQ 792
           M  F  GY  + EE +        +   EMVVV D+   SMC HHL+P+ G+  + Y+P 
Sbjct: 1   MTEFLDGYALTPEEAIGTVYPAPPDSAGEMVVVTDLRFHSMCPHHLLPYEGRAHVAYVPG 60

Query: 793 GXILG 807
             ++G
Sbjct: 61  KHVVG 65


>UniRef50_Q19Z80 Cluster: Gp6; n=4; root|Rep: Gp6 - Mycobacterium
           phage Qyrzula
          Length = 191

 Score = 48.8 bits (111), Expect = 2e-04
 Identities = 25/75 (33%), Positives = 38/75 (50%), Gaps = 2/75 (2%)
 Frame = +1

Query: 595 TPERAAKAMLFFTKGYXQSLEEVLNNAIFDEDTDEMVVVKDIEMFSMCEHHLVPFYGKVS 774
           TP R+AKA      GY +   + L       D    V++  +++ SMC HHL+PF G  +
Sbjct: 29  TPLRSAKAWSDILSGYREDPADHLEVTFSAPDDPGQVILAGVQLQSMCAHHLLPFTGMAT 88

Query: 775 IGYLPQ--GXILGLS 813
           + Y P     ++GLS
Sbjct: 89  VAYRPSPGDRVVGLS 103


>UniRef50_Q83FV8 Cluster: GTP cyclohydrolase I; n=2; Tropheryma
           whipplei|Rep: GTP cyclohydrolase I - Tropheryma whipplei
           (strain Twist) (Whipple's bacillus)
          Length = 181

 Score = 48.0 bits (109), Expect = 3e-04
 Identities = 30/102 (29%), Positives = 50/102 (49%)
 Frame = +1

Query: 586 LLKTPERAAKAMLFFTKGYXQSLEEVLNNAIFDEDTDEMVVVKDIEMFSMCEHHLVPFYG 765
           L +TP  A+  +     G   +  + L + I +     +V+++DI   S+CEHHL+PF G
Sbjct: 30  LKETPSIASSGLESLISGSETNPADCLVDLIPNTQKG-IVILRDIPFRSICEHHLLPFVG 88

Query: 766 KVSIGYLPQGXILGLSNWPGSWKYSPAGLQVXXRLTXXIAIA 891
             ++ Y P   + GL N     + +   L +  R+T  IA A
Sbjct: 89  TANLLYEPGKFLAGLGNLTSLVRCAARRLSIQERVTDQIADA 130


>UniRef50_Q54768 Cluster: Putative uncharacterized protein; n=1;
           Synechococcus elongatus PCC 7942|Rep: Putative
           uncharacterized protein - Synechococcus sp. (strain PCC
           7942) (Anacystis nidulans R2)
          Length = 227

 Score = 47.2 bits (107), Expect = 6e-04
 Identities = 23/79 (29%), Positives = 38/79 (48%)
 Frame = -1

Query: 813 AETQNXXLWQVPDGDLSVKRHQMMFAH*KHLDILNDHHLVRVFIEDGVVQNLFQALXVSF 634
           A+  N  +  V D + + +R  ++F   +  D+ + HH V  F+EDG V  + Q L V+ 
Sbjct: 97  AQADNLLVGDVSDVNFAHERQHVVFTKAEGGDVTHQHHFVVTFVEDGAVDQVIQGLAVAA 156

Query: 633 REEEHSFGGTFGRLQEPLP 577
            ++       F   QEP P
Sbjct: 157 GQKAIGLSDPFRGFQEPFP 175


>UniRef50_Q8XZK8 Cluster: GTP cyclohydrolase I; n=29;
           Betaproteobacteria|Rep: GTP cyclohydrolase I - Ralstonia
           solanacearum (Pseudomonas solanacearum)
          Length = 209

 Score = 47.2 bits (107), Expect = 6e-04
 Identities = 20/57 (35%), Positives = 32/57 (56%)
 Frame = +1

Query: 637 GYXQSLEEVLNNAIFDEDTDEMVVVKDIEMFSMCEHHLVPFYGKVSIGYLPQGXILG 807
           GY     E L +  F++   +MV+++ I +  +C HHL+PF G   + YLP G + G
Sbjct: 68  GYDIDPAEALGHG-FEDPRRDMVIIRSIAVHGVCPHHLLPFRGVAHVAYLPDGRLHG 123


>UniRef50_A7HBJ5 Cluster: GTP cyclohydrolase I; n=2;
           Anaeromyxobacter|Rep: GTP cyclohydrolase I -
           Anaeromyxobacter sp. Fw109-5
          Length = 219

 Score = 46.8 bits (106), Expect = 8e-04
 Identities = 27/72 (37%), Positives = 37/72 (51%), Gaps = 1/72 (1%)
 Frame = +1

Query: 595 TPERAAKAMLF-FTKGYXQSLEEVLNNAIFDEDTDEMVVVKDIEMFSMCEHHLVPFYGKV 771
           T  R A+A L     GY +   E+L +AI     D +V V  I   S+C HHL+P  G  
Sbjct: 49  THRRVAQAWLEDLVDGYRRDPAEILADAIPSPSRD-LVAVTGIAFHSVCPHHLLPSRGVA 107

Query: 772 SIGYLPQGXILG 807
            + YLP G ++G
Sbjct: 108 HVAYLPGGRVVG 119


>UniRef50_Q7XM20 Cluster: OSJNBa0084K01.11 protein; n=4; Oryza
           sativa|Rep: OSJNBa0084K01.11 protein - Oryza sativa
           subsp. japonica (Rice)
          Length = 451

 Score = 45.6 bits (103), Expect = 0.002
 Identities = 24/56 (42%), Positives = 32/56 (57%), Gaps = 2/56 (3%)
 Frame = +1

Query: 730 SMCEHHLVPFYGKVSIGYLP--QGXILGLSNWPGSWKYSPAGLQVXXRLTXXIAIA 891
           + CEHHL+PFYG V IGYL    G ++  S++     +    LQV  R+T  IA A
Sbjct: 333 AQCEHHLLPFYGVVHIGYLDGGDGEVIDRSHFQALVHFYGCKLQVQERMTRQIAEA 388


>UniRef50_Q2GDH9 Cluster: GTP cyclohydrolase I; n=1; Neorickettsia
           sennetsu str. Miyayama|Rep: GTP cyclohydrolase I -
           Neorickettsia sennetsu (strain Miyayama)
          Length = 180

 Score = 45.2 bits (102), Expect = 0.002
 Identities = 22/66 (33%), Positives = 34/66 (51%)
 Frame = +1

Query: 694 DEMVVVKDIEMFSMCEHHLVPFYGKVSIGYLPQGXILGLSNWPGSWKYSPAGLQVXXRLT 873
           + ++V+K     S CEHH++P  G +SIGY+P   I  L +           LQ+  R+ 
Sbjct: 62  ESLLVLKRTPFLSFCEHHVLPISGYISIGYIPDKSITSLGSLGRLVSACTKRLQLQERIC 121

Query: 874 XXIAIA 891
             IA+A
Sbjct: 122 AQIALA 127


>UniRef50_A5GUC6 Cluster: GTP cyclohydrolase I; n=28;
           Cyanobacteria|Rep: GTP cyclohydrolase I - Synechococcus
           sp. (strain RCC307)
          Length = 262

 Score = 41.5 bits (93), Expect = 0.028
 Identities = 21/59 (35%), Positives = 30/59 (50%), Gaps = 2/59 (3%)
 Frame = +1

Query: 685 EDTDEMVVVKDIEMFSMCEHHLVPFYGKVSIGYLPQGXILGLSNWP--GSWKYSPAGLQ 855
           ++ DE+  V  I + S C HHLVP  G   IG  P   ++GLS +     W +S   +Q
Sbjct: 130 KNLDEIYTVGPITVRSACSHHLVPILGNCWIGIKPGSSVIGLSKFARVADWVFSRPHIQ 188


>UniRef50_UPI0000F1DBDC Cluster: PREDICTED: similar to GTP
           cyclohydrolase I (form A; N-terminus), partial; n=1;
           Danio rerio|Rep: PREDICTED: similar to GTP
           cyclohydrolase I (form A; N-terminus), partial - Danio
           rerio
          Length = 115

 Score = 40.7 bits (91), Expect = 0.049
 Identities = 19/31 (61%), Positives = 22/31 (70%)
 Frame = +1

Query: 562 GRTLKGQGLLKTPERAAKAMLFFTKGYXQSL 654
           G   + QGLLKTP RAA AM FFTKGY + +
Sbjct: 84  GEDPQRQGLLKTPWRAATAMQFFTKGYQEKI 114



 Score = 35.1 bits (77), Expect = 2.5
 Identities = 15/29 (51%), Positives = 20/29 (68%)
 Frame = +3

Query: 507 EALLPDMANSYRLLLTGLGEDPERAGALE 593
           E  LP +A +Y  +L GLGEDP+R G L+
Sbjct: 66  EMSLPSIAAAYTTILRGLGEDPQRQGLLK 94


>UniRef50_A7JLM6 Cluster: GTP cyclohydrolase I; n=11; Francisella
           tularensis|Rep: GTP cyclohydrolase I - Francisella
           tularensis subsp. novicida GA99-3548
          Length = 207

 Score = 39.1 bits (87), Expect = 0.15
 Identities = 19/58 (32%), Positives = 29/58 (50%), Gaps = 1/58 (1%)
 Frame = +1

Query: 712 KDIEMFSMCEHHLVPFYGKVSIGYLPQ-GXILGLSNWPGSWKYSPAGLQVXXRLTXXI 882
           K+I + S CEHH VPF G   + ++P+   I+GL        +     Q+  R+T  I
Sbjct: 103 KNITIMSFCEHHFVPFEGTAEVSFIPKNNNIIGLCRINSICDFFSRRPQIQERMTAQI 160


>UniRef50_A4SVK2 Cluster: GTP cyclohydrolase I; n=20; Bacteria|Rep:
           GTP cyclohydrolase I - Polynucleobacter sp. QLW-P1DMWA-1
          Length = 262

 Score = 39.1 bits (87), Expect = 0.15
 Identities = 17/44 (38%), Positives = 28/44 (63%), Gaps = 2/44 (4%)
 Frame = +1

Query: 694 DEMVVVKDIEMFSMCEHHLVPFYGKVSIGYLP--QGXILGLSNW 819
           +E+++V  I + S C HHL P  G++ IG LP  +  ++GLS +
Sbjct: 136 NELMIVGPITIRSACSHHLCPIMGRIWIGVLPSKESALIGLSKY 179


>UniRef50_Q7N3C4 Cluster: Similarities with GTP cyclohydrolase I;
           n=1; Photorhabdus luminescens subsp. laumondii|Rep:
           Similarities with GTP cyclohydrolase I - Photorhabdus
           luminescens subsp. laumondii
          Length = 234

 Score = 35.9 bits (79), Expect = 1.4
 Identities = 27/77 (35%), Positives = 37/77 (48%), Gaps = 4/77 (5%)
 Frame = +1

Query: 595 TPERAAKA-MLFFTKGYXQSLEEVLNNAIFDEDTDEMVVVKD-IEMFSMCEHHLVPFYGK 768
           TP R AKA +L   KG  + +  +     F  D  + +V    I + SMC HH     G 
Sbjct: 73  TPRRVAKAYVLDLWKGRYKPMGPITT---FPADNYDGIVFDGWIALDSMCSHHHQAISGY 129

Query: 769 VSIGYLPQ--GXILGLS 813
           V + Y+P   G +LGLS
Sbjct: 130 VHVAYMPSQYGRVLGLS 146


>UniRef50_A7INF0 Cluster: Rare lipoprotein A; n=1; Xanthobacter
           autotrophicus Py2|Rep: Rare lipoprotein A - Xanthobacter
           sp. (strain Py2)
          Length = 314

 Score = 35.1 bits (77), Expect = 2.5
 Identities = 26/65 (40%), Positives = 32/65 (49%)
 Frame = -3

Query: 604 VRASSRAPALSGSSPRPVSRSLYELAMSGNNASLVGGLWSSSRSWWKVQFS*PGVVEVLG 425
           VRA   +   S  +P P SR  Y+L  SG+ AS  G +  +S S W    S P  V  LG
Sbjct: 249 VRAVPASAPPSAEAPIPPSRP-YDLGTSGSPASNAGSVAVASASGWS---SGPAPVSGLG 304

Query: 424 VIGVP 410
             GVP
Sbjct: 305 FAGVP 309


>UniRef50_Q5AW97 Cluster: Putative uncharacterized protein; n=1;
           Emericella nidulans|Rep: Putative uncharacterized
           protein - Emericella nidulans (Aspergillus nidulans)
          Length = 643

 Score = 35.1 bits (77), Expect = 2.5
 Identities = 28/82 (34%), Positives = 37/82 (45%), Gaps = 8/82 (9%)
 Frame = +3

Query: 303 NGDAPQ---KGSFVGKYKKA-----PEALKSFNLADAESELEVPGTPMTPRTSTTPGHEN 458
           NG  P+    GS + K+ K      P+A K    AD E   ++P  P T  +ST      
Sbjct: 385 NGALPEGSDTGSVLPKFSKTISRRFPKA-KLVTKADVEVAEDMPTRPSTGVSSTLKSFRK 443

Query: 459 CTFHHDLELDHRPPTREALLPD 524
               H  +L  + PTREAL PD
Sbjct: 444 SRHGHCQQLKQQEPTREALPPD 465


>UniRef50_Q02495 Cluster: Homeodomain protein; n=1; Schizophyllum
           commune|Rep: Homeodomain protein - Schizophyllum commune
           (Bracket fungus)
          Length = 640

 Score = 34.7 bits (76), Expect = 3.3
 Identities = 22/49 (44%), Positives = 22/49 (44%), Gaps = 1/49 (2%)
 Frame = -1

Query: 585 PLPFQGPPPGR*VEACMS*PCPVTTPPWWAVC-GPVPGHGGRCSSRDQA 442
           PLP   PPPGR      S PCP T      VC G  P    R S R QA
Sbjct: 276 PLPSYVPPPGRSDPPAPSQPCPTTLGSSPQVCAGKFPAPSTRESRRSQA 324


>UniRef50_UPI00015B6146 Cluster: PREDICTED: similar to
           ENSANGP00000009149; n=1; Nasonia vitripennis|Rep:
           PREDICTED: similar to ENSANGP00000009149 - Nasonia
           vitripennis
          Length = 1329

 Score = 33.9 bits (74), Expect = 5.7
 Identities = 17/47 (36%), Positives = 22/47 (46%)
 Frame = +1

Query: 742 HHLVPFYGKVSIGYLPQGXILGLSNWPGSWKYSPAGLQVXXRLTXXI 882
           H L+   G V+      G I G    PG W+YS  GLQ+   +T  I
Sbjct: 19  HALLDGSGSVNAETFTLGYITGSKRRPGDWEYSRPGLQISGAITLAI 65


>UniRef50_UPI00006C1A5A Cluster: PREDICTED: hypothetical protein;
           n=2; Homo/Pan/Gorilla group|Rep: PREDICTED: hypothetical
           protein - Homo sapiens
          Length = 312

 Score = 33.9 bits (74), Expect = 5.7
 Identities = 25/74 (33%), Positives = 31/74 (41%), Gaps = 1/74 (1%)
 Frame = -1

Query: 570 GPPPGR*VEACMS*PCPVTTPPWWAVCGPVPGHGGRCSSRDQAWSKSSASLAFRALQVHF 391
           GPPP    E  +  P      P  + CGP  GHGG  ++      KSS       L    
Sbjct: 20  GPPPVNKPEMRLLCPSGHNDSPQLSTCGPTKGHGGDVTASLLPVLKSSHQTP--TLSARL 77

Query: 390 P-HRPS*SSSGLLE 352
           P +RP  SS G L+
Sbjct: 78  PANRPDMSSHGALQ 91


>UniRef50_A6RXW6 Cluster: Putative uncharacterized protein; n=1;
           Botryotinia fuckeliana B05.10|Rep: Putative
           uncharacterized protein - Botryotinia fuckeliana B05.10
          Length = 1213

 Score = 33.9 bits (74), Expect = 5.7
 Identities = 16/49 (32%), Positives = 26/49 (53%)
 Frame = +3

Query: 345 KKAPEALKSFNLADAESELEVPGTPMTPRTSTTPGHENCTFHHDLELDH 491
           +KAPEAL   N   +     +P TP +PR+       +   HH++E+D+
Sbjct: 127 QKAPEALTVSNYPLSPKNTSIPNTP-SPRSEANDKINSIITHHEIEIDN 174


>UniRef50_UPI00005A0D93 Cluster: PREDICTED: similar to Zinc finger
            protein 469; n=2; Canis lupus familiaris|Rep: PREDICTED:
            similar to Zinc finger protein 469 - Canis familiaris
          Length = 3682

 Score = 33.5 bits (73), Expect = 7.5
 Identities = 30/94 (31%), Positives = 40/94 (42%), Gaps = 1/94 (1%)
 Frame = +3

Query: 327  SFVGKYKKAPEALKSFNLADAESELEVPGTPMTPRTSTTPGHENCTFHHDLELDHRPPTR 506
            +F+G   +    +K   +A+ ES+L+  G   TP    T GH   T       D   PT 
Sbjct: 1454 AFMGNLSEDELEIKRL-VAELESQLQSKGVHDTPELLCTAGHAGRT---HTGTDAPLPTH 1509

Query: 507  EALLPDMANSYRLLLTGLGED-PERAGALEDART 605
            +A  P   +     LTGLGE  P   GA   A T
Sbjct: 1510 QAASPPRDSFPEADLTGLGESTPHPEGAEAAAAT 1543


>UniRef50_Q9AB50 Cluster: Hydrolase, alpha/beta hydrolase fold
           family; n=1; Caulobacter vibrioides|Rep: Hydrolase,
           alpha/beta hydrolase fold family - Caulobacter
           crescentus (Caulobacter vibrioides)
          Length = 276

 Score = 33.5 bits (73), Expect = 7.5
 Identities = 15/44 (34%), Positives = 20/44 (45%)
 Frame = +1

Query: 433 LRPRLVTRTAPSTMTWNWTTDRPPGRRCYRTWLTHTGFYSPAWG 564
           L P L   TAP+T+ W W +  P     +  W  + G Y P  G
Sbjct: 204 LTPELAKITAPTTVVWAWNSSMPAPAAMFSGW--YQGAYGPLKG 245


>UniRef50_Q74K42 Cluster: Levansucrase; n=1; Lactobacillus
           johnsonii|Rep: Levansucrase - Lactobacillus johnsonii
          Length = 797

 Score = 33.5 bits (73), Expect = 7.5
 Identities = 19/70 (27%), Positives = 29/70 (41%), Gaps = 2/70 (2%)
 Frame = +3

Query: 309 DAPQKGSFVGKYKKAPE--ALKSFNLADAESELEVPGTPMTPRTSTTPGHENCTFHHDLE 482
           DAP   +  G++ K  +   +  +NL   +    +P  P TP T TTP         ++ 
Sbjct: 679 DAPNSAALPGEWGKPVDWDLIGGYNLKPHQPVTPIPNVPTTPETPTTPDKPEVPTTPEVP 738

Query: 483 LDHRPPTREA 512
                PT EA
Sbjct: 739 TTPETPTPEA 748


>UniRef50_A6Q395 Cluster: 2-oxoglutarate ferredoxin oxidoreductase,
           alpha subunit; n=21; root|Rep: 2-oxoglutarate ferredoxin
           oxidoreductase, alpha subunit - Nitratiruptor sp.
           (strain SB155-2)
          Length = 382

 Score = 33.5 bits (73), Expect = 7.5
 Identities = 18/49 (36%), Positives = 23/49 (46%)
 Frame = +3

Query: 495 PPTREALLPDMANSYRLLLTGLGEDPERAGALEDARTCRQSYALLHERI 641
           P  + A++P M   YR  LTGL   P      EDA  C+     LH +I
Sbjct: 213 PQDKPAVIPPMFQGYRFHLTGLHHGP-TGFPTEDAEICQNLIERLHRKI 260


>UniRef50_A3YCH8 Cluster: Lipid A biosynthesis acyltransferase; n=1;
           Marinomonas sp. MED121|Rep: Lipid A biosynthesis
           acyltransferase - Marinomonas sp. MED121
          Length = 297

 Score = 33.5 bits (73), Expect = 7.5
 Identities = 21/70 (30%), Positives = 32/70 (45%), Gaps = 1/70 (1%)
 Frame = +1

Query: 544 FYSP-AWGRTLKGQGLLKTPERAAKAMLFFTKGYXQSLEEVLNNAIFDEDTDEMVVVKDI 720
           FY   A+  TL  Q + KT  +A     F  KG  + + E ++   + ED DE V   + 
Sbjct: 205 FYGQQAYSMTLTSQLVNKTGAKAFIGAAFRVKGGYKVIMEPVDEGFYSEDVDESVAAMNR 264

Query: 721 EMFSMCEHHL 750
            +  + EH L
Sbjct: 265 SIEKLAEHGL 274


>UniRef50_A5AVA6 Cluster: Putative uncharacterized protein; n=3;
           Vitis vinifera|Rep: Putative uncharacterized protein -
           Vitis vinifera (Grape)
          Length = 987

 Score = 33.1 bits (72), Expect = 9.9
 Identities = 23/88 (26%), Positives = 41/88 (46%), Gaps = 2/88 (2%)
 Frame = +1

Query: 583 GLLKTPERAAKAMLFFTKGYXQSLEEVLNN--AIFDEDTDEMVVVKDIEMFSMCEHHLVP 756
           GL   P    K ML       + + EV  +   I+    DE +V  ++ +    E  LV 
Sbjct: 93  GLCNAPATFQKCMLSIFSDMVERIMEVFMDDITIYGSAFDECLVNLEVVLNRCIEKDLVL 152

Query: 757 FYGKVSIGYLPQGXILGLSNWPGSWKYS 840
            +G+ +I + P+G  LG+S+   + K++
Sbjct: 153 NWGRNAISWYPKGLSLGISSQRKALKWT 180


  Database: uniref50
    Posted date:  Oct 5, 2007 11:19 AM
  Number of letters in database: 575,637,011
  Number of sequences in database:  1,657,284
  
Lambda     K      H
   0.318    0.134    0.401 

Gapped
Lambda     K      H
   0.279   0.0580    0.190 


Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 883,695,047
Number of Sequences: 1657284
Number of extensions: 19520031
Number of successful extensions: 54860
Number of sequences better than 10.0: 93
Number of HSP's better than 10.0 without gapping: 51310
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 54696
length of database: 575,637,011
effective HSP length: 100
effective length of database: 409,908,611
effective search space used: 81571813589
frameshift window, decay const: 40,  0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)

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