Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= MFBP01_F_P16
(953 letters)
Database: human
237,096 sequences; 76,859,062 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
X68836-1|CAA48726.1| 395|Homo sapiens S-adenosylmethionine synt... 244 4e-64
DQ083239-1|AAY85355.1| 395|Homo sapiens methionine adenosyltran... 244 4e-64
BC001854-1|AAH01854.1| 395|Homo sapiens methionine adenosyltran... 244 4e-64
BC001686-1|AAH01686.1| 395|Homo sapiens methionine adenosyltran... 244 4e-64
AC016753-1|AAY24339.1| 395|Homo sapiens unknown protein. 244 4e-64
X69078-1|CAA48822.1| 395|Homo sapiens methionine adenosyltransf... 234 4e-61
D49357-1|BAA08355.1| 395|Homo sapiens S-adenosylmethionine synt... 234 4e-61
BC018359-1|AAH18359.1| 395|Homo sapiens methionine adenosyltran... 234 4e-61
AL359195-2|CAI13695.1| 395|Homo sapiens methionine adenosyltran... 234 4e-61
AL359195-3|CAI13696.1| 145|Homo sapiens methionine adenosyltran... 90 1e-17
>X68836-1|CAA48726.1| 395|Homo sapiens S-adenosylmethionine
synthetase protein.
Length = 395
Score = 244 bits (597), Expect = 4e-64
Identities = 128/209 (61%), Positives = 150/209 (71%), Gaps = 1/209 (0%)
Frame = +3
Query: 132 MNGYAKTNG-HSYDMEDGSVFLFTSESVGEGHPDKMCDQISXAILDXHLNQDPDAKVACE 308
MNG + NG H +E+G+ FLFTSESVGEGHPDK+CDQIS A+LD HL QDPDAKVACE
Sbjct: 1 MNG--QLNGFHEAFIEEGT-FLFTSESVGEGHPDKICDQISDAVLDAHLQQDPDAKVACE 57
Query: 309 TITKTGMVLLCGEITSKANVDYQKVVRETVKHIGYDDSSKGFDWRTLNLLVAIEEQVQIL 488
T+ KTGM+LL GEITS+A VDYQKVVRE VKHIGYDDSSKGFD++T N+LVA+E+Q +
Sbjct: 58 TVAKTGMILLAGEITSRAAVDYQKVVREAVKHIGYDDSSKGFDYKTCNVLVALEQQSPDI 117
Query: 489 LRVCILTXXK*I*GLEIRA*CSVMQPDETEECMPLTXXLAHKLNXKIAELTRNGEFWXXR 668
+ L + G + DETEECMPLT LAHKLN K+AEL RNG R
Sbjct: 118 AQGVHLDRNEEDIGAGDQGLMFGYATDETEECMPLTIVLAHKLNAKLAELRRNGTLPWLR 177
Query: 669 PHSKTQVTCQYVFAGGAXSPXXVHTVXLS 755
P SKTQVT QY+ GA P VHT+ +S
Sbjct: 178 PDSKTQVTVQYMQDRGAVLPIRVHTIVIS 206
>DQ083239-1|AAY85355.1| 395|Homo sapiens methionine
adenosyltransferase II protein.
Length = 395
Score = 244 bits (597), Expect = 4e-64
Identities = 128/209 (61%), Positives = 150/209 (71%), Gaps = 1/209 (0%)
Frame = +3
Query: 132 MNGYAKTNG-HSYDMEDGSVFLFTSESVGEGHPDKMCDQISXAILDXHLNQDPDAKVACE 308
MNG + NG H +E+G+ FLFTSESVGEGHPDK+CDQIS A+LD HL QDPDAKVACE
Sbjct: 1 MNG--QLNGFHEAFIEEGT-FLFTSESVGEGHPDKICDQISDAVLDAHLQQDPDAKVACE 57
Query: 309 TITKTGMVLLCGEITSKANVDYQKVVRETVKHIGYDDSSKGFDWRTLNLLVAIEEQVQIL 488
T+ KTGM+LL GEITS+A VDYQKVVRE VKHIGYDDSSKGFD++T N+LVA+E+Q +
Sbjct: 58 TVAKTGMILLAGEITSRAAVDYQKVVREAVKHIGYDDSSKGFDYKTCNVLVALEQQSPDI 117
Query: 489 LRVCILTXXK*I*GLEIRA*CSVMQPDETEECMPLTXXLAHKLNXKIAELTRNGEFWXXR 668
+ L + G + DETEECMPLT LAHKLN K+AEL RNG R
Sbjct: 118 AQGVHLDRNEEDIGAGDQGLMFGYATDETEECMPLTIVLAHKLNAKLAELRRNGTLPWLR 177
Query: 669 PHSKTQVTCQYVFAGGAXSPXXVHTVXLS 755
P SKTQVT QY+ GA P VHT+ +S
Sbjct: 178 PDSKTQVTVQYMQDRGAVLPIRVHTIVIS 206
>BC001854-1|AAH01854.1| 395|Homo sapiens methionine
adenosyltransferase II, alpha protein.
Length = 395
Score = 244 bits (597), Expect = 4e-64
Identities = 128/209 (61%), Positives = 150/209 (71%), Gaps = 1/209 (0%)
Frame = +3
Query: 132 MNGYAKTNG-HSYDMEDGSVFLFTSESVGEGHPDKMCDQISXAILDXHLNQDPDAKVACE 308
MNG + NG H +E+G+ FLFTSESVGEGHPDK+CDQIS A+LD HL QDPDAKVACE
Sbjct: 1 MNG--QLNGFHEAFIEEGT-FLFTSESVGEGHPDKICDQISDAVLDAHLQQDPDAKVACE 57
Query: 309 TITKTGMVLLCGEITSKANVDYQKVVRETVKHIGYDDSSKGFDWRTLNLLVAIEEQVQIL 488
T+ KTGM+LL GEITS+A VDYQKVVRE VKHIGYDDSSKGFD++T N+LVA+E+Q +
Sbjct: 58 TVAKTGMILLAGEITSRAAVDYQKVVREAVKHIGYDDSSKGFDYKTCNVLVALEQQSPDI 117
Query: 489 LRVCILTXXK*I*GLEIRA*CSVMQPDETEECMPLTXXLAHKLNXKIAELTRNGEFWXXR 668
+ L + G + DETEECMPLT LAHKLN K+AEL RNG R
Sbjct: 118 AQGVHLDRNEEDIGAGDQGLMFGYATDETEECMPLTIVLAHKLNAKLAELRRNGTLPWLR 177
Query: 669 PHSKTQVTCQYVFAGGAXSPXXVHTVXLS 755
P SKTQVT QY+ GA P VHT+ +S
Sbjct: 178 PDSKTQVTVQYMQDRGAVLPIRVHTIVIS 206
>BC001686-1|AAH01686.1| 395|Homo sapiens methionine
adenosyltransferase II, alpha protein.
Length = 395
Score = 244 bits (597), Expect = 4e-64
Identities = 128/209 (61%), Positives = 150/209 (71%), Gaps = 1/209 (0%)
Frame = +3
Query: 132 MNGYAKTNG-HSYDMEDGSVFLFTSESVGEGHPDKMCDQISXAILDXHLNQDPDAKVACE 308
MNG + NG H +E+G+ FLFTSESVGEGHPDK+CDQIS A+LD HL QDPDAKVACE
Sbjct: 1 MNG--QLNGFHEAFIEEGT-FLFTSESVGEGHPDKICDQISDAVLDAHLQQDPDAKVACE 57
Query: 309 TITKTGMVLLCGEITSKANVDYQKVVRETVKHIGYDDSSKGFDWRTLNLLVAIEEQVQIL 488
T+ KTGM+LL GEITS+A VDYQKVVRE VKHIGYDDSSKGFD++T N+LVA+E+Q +
Sbjct: 58 TVAKTGMILLAGEITSRAAVDYQKVVREAVKHIGYDDSSKGFDYKTCNVLVALEQQSPDI 117
Query: 489 LRVCILTXXK*I*GLEIRA*CSVMQPDETEECMPLTXXLAHKLNXKIAELTRNGEFWXXR 668
+ L + G + DETEECMPLT LAHKLN K+AEL RNG R
Sbjct: 118 AQGVHLDRNEEDIGAGDQGLMFGYATDETEECMPLTIVLAHKLNAKLAELRRNGTLPWLR 177
Query: 669 PHSKTQVTCQYVFAGGAXSPXXVHTVXLS 755
P SKTQVT QY+ GA P VHT+ +S
Sbjct: 178 PDSKTQVTVQYMQDRGAVLPIRVHTIVIS 206
>AC016753-1|AAY24339.1| 395|Homo sapiens unknown protein.
Length = 395
Score = 244 bits (597), Expect = 4e-64
Identities = 128/209 (61%), Positives = 150/209 (71%), Gaps = 1/209 (0%)
Frame = +3
Query: 132 MNGYAKTNG-HSYDMEDGSVFLFTSESVGEGHPDKMCDQISXAILDXHLNQDPDAKVACE 308
MNG + NG H +E+G+ FLFTSESVGEGHPDK+CDQIS A+LD HL QDPDAKVACE
Sbjct: 1 MNG--QLNGFHEAFIEEGT-FLFTSESVGEGHPDKICDQISDAVLDAHLQQDPDAKVACE 57
Query: 309 TITKTGMVLLCGEITSKANVDYQKVVRETVKHIGYDDSSKGFDWRTLNLLVAIEEQVQIL 488
T+ KTGM+LL GEITS+A VDYQKVVRE VKHIGYDDSSKGFD++T N+LVA+E+Q +
Sbjct: 58 TVAKTGMILLAGEITSRAAVDYQKVVREAVKHIGYDDSSKGFDYKTCNVLVALEQQSPDI 117
Query: 489 LRVCILTXXK*I*GLEIRA*CSVMQPDETEECMPLTXXLAHKLNXKIAELTRNGEFWXXR 668
+ L + G + DETEECMPLT LAHKLN K+AEL RNG R
Sbjct: 118 AQGVHLDRNEEDIGAGDQGLMFGYATDETEECMPLTIVLAHKLNAKLAELRRNGTLPWLR 177
Query: 669 PHSKTQVTCQYVFAGGAXSPXXVHTVXLS 755
P SKTQVT QY+ GA P VHT+ +S
Sbjct: 178 PDSKTQVTVQYMQDRGAVLPIRVHTIVIS 206
>X69078-1|CAA48822.1| 395|Homo sapiens methionine
adenosyltransferase protein.
Length = 395
Score = 234 bits (572), Expect = 4e-61
Identities = 115/197 (58%), Positives = 144/197 (73%)
Frame = +3
Query: 165 YDMEDGSVFLFTSESVGEGHPDKMCDQISXAILDXHLNQDPDAKVACETITKTGMVLLCG 344
+ + +G VF+FTSESVGEGHPDK+CDQIS A+LD HL QDP+AKVACET+ KTGMVLLCG
Sbjct: 11 HSLSEG-VFMFTSESVGEGHPDKICDQISDAVLDAHLKQDPNAKVACETVCKTGMVLLCG 69
Query: 345 EITSKANVDYQKVVRETVKHIGYDDSSKGFDWRTLNLLVAIEEQVQILLRVCILTXXK*I 524
EITS A VDYQ+VVR+T+KHIGYDDS+KGFD++T N+LVA+E+Q + + L +
Sbjct: 70 EITSMAMVDYQRVVRDTIKHIGYDDSAKGFDFKTCNVLVALEQQSPDIAQCVHLDRNEED 129
Query: 525 *GLEIRA*CSVMQPDETEECMPLTXXLAHKLNXKIAELTRNGEFWXXRPHSKTQVTCQYV 704
G + DETEECMPLT LAHKLN ++A+L R+G RP SKTQVT QY+
Sbjct: 130 VGAGDQGLMFGYATDETEECMPLTIILAHKLNARMADLRRSGLLPWLRPDSKTQVTVQYM 189
Query: 705 FAGGAXSPXXVHTVXLS 755
GA P +HT+ +S
Sbjct: 190 QDNGAVIPVRIHTIVIS 206
>D49357-1|BAA08355.1| 395|Homo sapiens S-adenosylmethionine
synthetase protein.
Length = 395
Score = 234 bits (572), Expect = 4e-61
Identities = 115/197 (58%), Positives = 144/197 (73%)
Frame = +3
Query: 165 YDMEDGSVFLFTSESVGEGHPDKMCDQISXAILDXHLNQDPDAKVACETITKTGMVLLCG 344
+ + +G VF+FTSESVGEGHPDK+CDQIS A+LD HL QDP+AKVACET+ KTGMVLLCG
Sbjct: 11 HSLSEG-VFMFTSESVGEGHPDKICDQISDAVLDAHLKQDPNAKVACETVCKTGMVLLCG 69
Query: 345 EITSKANVDYQKVVRETVKHIGYDDSSKGFDWRTLNLLVAIEEQVQILLRVCILTXXK*I 524
EITS A VDYQ+VVR+T+KHIGYDDS+KGFD++T N+LVA+E+Q + + L +
Sbjct: 70 EITSMAMVDYQRVVRDTIKHIGYDDSAKGFDFKTCNVLVALEQQSPDIAQCVHLDRNEED 129
Query: 525 *GLEIRA*CSVMQPDETEECMPLTXXLAHKLNXKIAELTRNGEFWXXRPHSKTQVTCQYV 704
G + DETEECMPLT LAHKLN ++A+L R+G RP SKTQVT QY+
Sbjct: 130 VGAGDQGLMFGYATDETEECMPLTIILAHKLNARMADLRRSGLLPWLRPDSKTQVTVQYM 189
Query: 705 FAGGAXSPXXVHTVXLS 755
GA P +HT+ +S
Sbjct: 190 QDNGAVIPVRIHTIVIS 206
>BC018359-1|AAH18359.1| 395|Homo sapiens methionine
adenosyltransferase I, alpha protein.
Length = 395
Score = 234 bits (572), Expect = 4e-61
Identities = 115/197 (58%), Positives = 144/197 (73%)
Frame = +3
Query: 165 YDMEDGSVFLFTSESVGEGHPDKMCDQISXAILDXHLNQDPDAKVACETITKTGMVLLCG 344
+ + +G VF+FTSESVGEGHPDK+CDQIS A+LD HL QDP+AKVACET+ KTGMVLLCG
Sbjct: 11 HSLSEG-VFMFTSESVGEGHPDKICDQISDAVLDAHLKQDPNAKVACETVCKTGMVLLCG 69
Query: 345 EITSKANVDYQKVVRETVKHIGYDDSSKGFDWRTLNLLVAIEEQVQILLRVCILTXXK*I 524
EITS A VDYQ+VVR+T+KHIGYDDS+KGFD++T N+LVA+E+Q + + L +
Sbjct: 70 EITSMAMVDYQRVVRDTIKHIGYDDSAKGFDFKTCNVLVALEQQSPDIAQCVHLDRNEED 129
Query: 525 *GLEIRA*CSVMQPDETEECMPLTXXLAHKLNXKIAELTRNGEFWXXRPHSKTQVTCQYV 704
G + DETEECMPLT LAHKLN ++A+L R+G RP SKTQVT QY+
Sbjct: 130 VGAGDQGLMFGYATDETEECMPLTIILAHKLNARMADLRRSGLLPWLRPDSKTQVTVQYM 189
Query: 705 FAGGAXSPXXVHTVXLS 755
GA P +HT+ +S
Sbjct: 190 QDNGAVIPVRIHTIVIS 206
>AL359195-2|CAI13695.1| 395|Homo sapiens methionine
adenosyltransferase I, alpha protein.
Length = 395
Score = 234 bits (572), Expect = 4e-61
Identities = 115/197 (58%), Positives = 144/197 (73%)
Frame = +3
Query: 165 YDMEDGSVFLFTSESVGEGHPDKMCDQISXAILDXHLNQDPDAKVACETITKTGMVLLCG 344
+ + +G VF+FTSESVGEGHPDK+CDQIS A+LD HL QDP+AKVACET+ KTGMVLLCG
Sbjct: 11 HSLSEG-VFMFTSESVGEGHPDKICDQISDAVLDAHLKQDPNAKVACETVCKTGMVLLCG 69
Query: 345 EITSKANVDYQKVVRETVKHIGYDDSSKGFDWRTLNLLVAIEEQVQILLRVCILTXXK*I 524
EITS A VDYQ+VVR+T+KHIGYDDS+KGFD++T N+LVA+E+Q + + L +
Sbjct: 70 EITSMAMVDYQRVVRDTIKHIGYDDSAKGFDFKTCNVLVALEQQSPDIAQCVHLDRNEED 129
Query: 525 *GLEIRA*CSVMQPDETEECMPLTXXLAHKLNXKIAELTRNGEFWXXRPHSKTQVTCQYV 704
G + DETEECMPLT LAHKLN ++A+L R+G RP SKTQVT QY+
Sbjct: 130 VGAGDQGLMFGYATDETEECMPLTIILAHKLNARMADLRRSGLLPWLRPDSKTQVTVQYM 189
Query: 705 FAGGAXSPXXVHTVXLS 755
GA P +HT+ +S
Sbjct: 190 QDNGAVIPVRIHTIVIS 206
>AL359195-3|CAI13696.1| 145|Homo sapiens methionine
adenosyltransferase I, alpha protein.
Length = 145
Score = 89.8 bits (213), Expect = 1e-17
Identities = 51/121 (42%), Positives = 71/121 (58%), Gaps = 3/121 (2%)
Frame = +3
Query: 402 HIGYDDSSK---GFDWRTLNLLVAIEEQVQILLRVCILTXXK*I*GLEIRA*CSVMQPDE 572
H+ D ++K GFD++T N+LVA+E+Q + + L + G + DE
Sbjct: 23 HLKQDPNAKVACGFDFKTCNVLVALEQQSPDIAQCVHLDRNEEDVGAGDQGLMFGYATDE 82
Query: 573 TEECMPLTXXLAHKLNXKIAELTRNGEFWXXRPHSKTQVTCQYVFAGGAXSPXXVHTVXL 752
TEECMPLT LAHKLN ++A+L R+G RP SKTQVT QY+ GA P +HT+ +
Sbjct: 83 TEECMPLTIILAHKLNARMADLRRSGLLPWLRPDSKTQVTVQYMQDNGAVIPVRIHTIVI 142
Query: 753 S 755
S
Sbjct: 143 S 143
Score = 69.7 bits (163), Expect = 1e-11
Identities = 33/48 (68%), Positives = 37/48 (77%)
Frame = +3
Query: 204 ESVGEGHPDKMCDQISXAILDXHLNQDPDAKVACETITKTGMVLLCGE 347
ESVGEGHPDK+CDQIS A+LD HL QDP+AKVAC KT VL+ E
Sbjct: 1 ESVGEGHPDKICDQISDAVLDAHLKQDPNAKVACGFDFKTCNVLVALE 48
Database: human
Posted date: Oct 23, 2007 1:18 PM
Number of letters in database: 76,859,062
Number of sequences in database: 237,096
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 117,191,598
Number of Sequences: 237096
Number of extensions: 2334546
Number of successful extensions: 7670
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 7233
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 7650
length of database: 76,859,062
effective HSP length: 90
effective length of database: 55,520,422
effective search space used: 12603135794
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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