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Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= MFBP01_F_L05
         (962 letters)

Database: uniref50 
           1,657,284 sequences; 575,637,011 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

UniRef50_UPI0000D569A3 Cluster: PREDICTED: similar to 5-formylte...   111   3e-23
UniRef50_P49914 Cluster: 5-formyltetrahydrofolate cyclo-ligase; ...   109   1e-22
UniRef50_A7SFC3 Cluster: Predicted protein; n=1; Nematostella ve...   100   5e-20
UniRef50_P80405 Cluster: 5-formyltetrahydrofolate cyclo-ligase; ...    97   4e-19
UniRef50_Q16S54 Cluster: 5-formyltetrahydrofolate cyclo-ligase; ...    87   8e-16
UniRef50_Q9W1R6 Cluster: CG11079-PA, isoform A; n=6; Diptera|Rep...    86   1e-15
UniRef50_Q9XWE6 Cluster: Putative 5-formyltetrahydrofolate cyclo...    82   2e-14
UniRef50_UPI0000E47106 Cluster: PREDICTED: hypothetical protein;...    79   2e-13
UniRef50_UPI0001553191 Cluster: PREDICTED: hypothetical protein;...    56   1e-06
UniRef50_A0L5J2 Cluster: 5-formyltetrahydrofolate cyclo-ligase; ...    56   2e-06
UniRef50_Q18VM6 Cluster: 5-formyltetrahydrofolate cyclo-ligase; ...    55   2e-06
UniRef50_A5DWB9 Cluster: Putative uncharacterized protein; n=1; ...    54   7e-06
UniRef50_Q97K31 Cluster: 5-formyltetrahydrofolate cyclo-ligase; ...    53   1e-05
UniRef50_Q97NE8 Cluster: 5-formyltetrahydrofolate cyclo-ligase f...    53   1e-05
UniRef50_A3LUI4 Cluster: 5,10-methenyltetrahydrofolate synthetas...    52   2e-05
UniRef50_A6LQ49 Cluster: 5-formyltetrahydrofolate cyclo-ligase; ...    52   2e-05
UniRef50_Q4AQ84 Cluster: 5-formyltetrahydrofolate cyclo-ligase; ...    52   3e-05
UniRef50_A5DQN3 Cluster: Putative uncharacterized protein; n=1; ...    51   4e-05
UniRef50_Q65HC6 Cluster: YqgN; n=1; Bacillus licheniformis ATCC ...    50   1e-04
UniRef50_Q21EV7 Cluster: 5-formyltetrahydrofolate cyclo-ligase; ...    50   1e-04
UniRef50_Q83F82 Cluster: 5-formyltetrahydrofolate cyclo-ligase f...    49   2e-04
UniRef50_Q7URX2 Cluster: 5-formyltetrahydrofolate cyclo-ligase; ...    48   4e-04
UniRef50_Q3AE50 Cluster: 5-formyltetrahydrofolate cyclo-ligase f...    48   4e-04
UniRef50_A6EYV6 Cluster: 5-formyltetrahydrofolate cyclo-ligase f...    48   5e-04
UniRef50_Q6CAN2 Cluster: Similar to sp|P40099 Saccharomyces cere...    48   5e-04
UniRef50_A3CVT9 Cluster: 5-formyltetrahydrofolate cyclo-ligase; ...    48   5e-04
UniRef50_Q9KD02 Cluster: 5-formyltetrahydrofolate cyclo-ligase; ...    47   8e-04
UniRef50_Q896J3 Cluster: 5-formyltetrahydrofolate cyclo-ligase; ...    47   8e-04
UniRef50_Q041X5 Cluster: 5-formyltetrahydrofolate cyclo-ligase; ...    46   0.001
UniRef50_Q1AWE3 Cluster: 5-formyltetrahydrofolate cyclo-ligase; ...    46   0.001
UniRef50_A3EWC9 Cluster: 5-formyltetrahydrofolate cyclo-ligase; ...    46   0.001
UniRef50_A6CNU5 Cluster: Possible 5-formyltetrahydrofolate cyclo...    46   0.002
UniRef50_A7I701 Cluster: 5-formyltetrahydrofolate cyclo-ligase; ...    46   0.002
UniRef50_A6VM34 Cluster: 5-formyltetrahydrofolate cyclo-ligase; ...    45   0.003
UniRef50_A6S3W0 Cluster: Putative uncharacterized protein; n=5; ...    45   0.003
UniRef50_A5Z6A8 Cluster: Putative uncharacterized protein; n=1; ...    45   0.003
UniRef50_Q03Y24 Cluster: 5-formyltetrahydrofolate cyclo-ligase; ...    44   0.004
UniRef50_Q6AQJ8 Cluster: Probable 5-formyltetrahydrofolate cyclo...    44   0.006
UniRef50_Q603N0 Cluster: 5-formyltetrahydrofolate cyclo-ligase f...    44   0.006
UniRef50_Q1WUH7 Cluster: 5-formyltetrahydrofolate cyclo-ligase; ...    44   0.006
UniRef50_Q1MQA3 Cluster: 5-formyltetrahydrofolate cyclo-ligase; ...    44   0.006
UniRef50_A3IGL7 Cluster: 5-formyltetrahydrofolate cyclo-ligase; ...    44   0.006
UniRef50_Q3XWC2 Cluster: 5-formyltetrahydrofolate cyclo-ligase; ...    44   0.008
UniRef50_A5N8A1 Cluster: 5-formyltetrahydrofolate cyclo-ligase-r...    44   0.008
UniRef50_A1SSJ1 Cluster: 5-formyltetrahydrofolate cyclo-ligase; ...    44   0.008
UniRef50_Q6FTS7 Cluster: Similar to sp|P40099 Saccharomyces cere...    44   0.008
UniRef50_Q41FV0 Cluster: 5-formyltetrahydrofolate cyclo-ligase; ...    43   0.010
UniRef50_A6NRP0 Cluster: Putative uncharacterized protein; n=1; ...    43   0.010
UniRef50_A4A119 Cluster: 5-formyltetrahydrofolate cyclo-ligase; ...    43   0.010
UniRef50_A3DEZ8 Cluster: 5-formyltetrahydrofolate cyclo-ligase; ...    43   0.010
UniRef50_A1U687 Cluster: 5-formyltetrahydrofolate cyclo-ligase; ...    43   0.010
UniRef50_Q6CX89 Cluster: Similarities with sp|P40099 Saccharomyc...    43   0.010
UniRef50_Q14L13 Cluster: Putative 5-formyltetrahydrofolate cyclo...    43   0.013
UniRef50_Q03G82 Cluster: 5-formyltetrahydrofolate cyclo-ligase; ...    42   0.018
UniRef50_A4AI88 Cluster: 5-formyltetrahydrofolate cyclo-ligase-r...    42   0.018
UniRef50_Q4K404 Cluster: 5-formyltetrahydrofolate cyclo-ligase f...    42   0.023
UniRef50_A6TVJ5 Cluster: 5-formyltetrahydrofolate cyclo-ligase; ...    42   0.023
UniRef50_A4SLF4 Cluster: 5-formyltetrahydrofolate cyclo-ligase f...    42   0.023
UniRef50_A1URD6 Cluster: 5,10-methenyltetrahydrofolate synthetas...    42   0.023
UniRef50_Q5KX52 Cluster: 5-formyltetrahydrofolate cyclo-ligase; ...    42   0.031
UniRef50_Q180V5 Cluster: Putative 5-formyltetrahydrofolate cyclo...    42   0.031
UniRef50_Q0YQW9 Cluster: 5-formyltetrahydrofolate cyclo-ligase; ...    42   0.031
UniRef50_Q0ALV8 Cluster: 5-formyltetrahydrofolate cyclo-ligase; ...    42   0.031
UniRef50_A4WE63 Cluster: 5-formyltetrahydrofolate cyclo-ligase; ...    42   0.031
UniRef50_Q7P0R7 Cluster: Probable 5-formyltetrahydrofolate cyclo...    41   0.041
UniRef50_Q57BF7 Cluster: 5-formyltetrahydrofolate cyclo-ligase f...    41   0.041
UniRef50_Q0SQM2 Cluster: 5-formyltetrahydrofolate cyclo-ligase f...    41   0.041
UniRef50_A1WW94 Cluster: 5-formyltetrahydrofolate cyclo-ligase; ...    41   0.041
UniRef50_A2SSS2 Cluster: 5-formyltetrahydrofolate cyclo-ligase; ...    41   0.041
UniRef50_Q8G439 Cluster: Putative uncharacterized protein; n=1; ...    41   0.054
UniRef50_Q7MTT7 Cluster: 5-formyltetrahydrofolate cyclo-ligase f...    41   0.054
UniRef50_Q5WH98 Cluster: 5-formyltetrahydrofolate cyclo-ligase; ...    41   0.054
UniRef50_A0W837 Cluster: 5-formyltetrahydrofolate cyclo-ligase; ...    41   0.054
UniRef50_P0AC29 Cluster: Uncharacterized protein ygfA; n=23; Ent...    41   0.054
UniRef50_A0RTU2 Cluster: 5-formyltetrahydrofolate cyclo-ligase; ...    40   0.072
UniRef50_Q72F49 Cluster: 5-formyltetrahydrofolate cyclo-ligase f...    40   0.095
UniRef50_Q31FB9 Cluster: 5-formyltetrahydrofolate cyclo-ligase; ...    40   0.095
UniRef50_Q2RGK7 Cluster: 5-formyltetrahydrofolate cyclo-ligase p...    40   0.095
UniRef50_O67621 Cluster: Putative uncharacterized protein; n=1; ...    40   0.095
UniRef50_Q40JH2 Cluster: 5-formyltetrahydrofolate cyclo-ligase; ...    40   0.095
UniRef50_Q3VT50 Cluster: 5-formyltetrahydrofolate cyclo-ligase; ...    40   0.095
UniRef50_Q1YVJ4 Cluster: 5-formyltetrahydrofolate cyclo-ligase f...    40   0.095
UniRef50_Q1V201 Cluster: 5-formyltetrahydrofolate cyclo-ligase; ...    40   0.095
UniRef50_A7IJU7 Cluster: 5-formyltetrahydrofolate cyclo-ligase; ...    40   0.095
UniRef50_A5VKU2 Cluster: 5-formyltetrahydrofolate cyclo-ligase; ...    40   0.095
UniRef50_Q83FP9 Cluster: Putative uncharacterized protein; n=2; ...    40   0.13 
UniRef50_Q74E28 Cluster: 5-formyltetrahydrofolate cyclo-ligase f...    40   0.13 
UniRef50_O83692 Cluster: 5,10-methenyltetrahydrofolate synthetas...    40   0.13 
UniRef50_Q0HZ35 Cluster: 5-formyltetrahydrofolate cyclo-ligase; ...    40   0.13 
UniRef50_A4E9T0 Cluster: Putative uncharacterized protein; n=1; ...    40   0.13 
UniRef50_P44905 Cluster: Uncharacterized protein HI0858; n=16; G...    40   0.13 
UniRef50_Q5HNZ9 Cluster: 5-formyltetrahydrofolate cyclo-ligase f...    39   0.17 
UniRef50_Q5FIZ8 Cluster: 5-formyltetrahydrofolate cyclo-ligase; ...    39   0.17 
UniRef50_Q1MZK4 Cluster: 5-formyltetrahydrofolate cyclo-ligase f...    39   0.17 
UniRef50_Q0RC09 Cluster: Putative ligase; n=1; Frankia alni ACN1...    39   0.17 
UniRef50_Q049I2 Cluster: 5-formyltetrahydrofolate cyclo-ligase; ...    39   0.17 
UniRef50_A0JYX4 Cluster: 5-formyltetrahydrofolate cyclo-ligase; ...    39   0.17 
UniRef50_Q9FYA5 Cluster: 5-formyltetrahydrofolate cyclo-ligase-l...    39   0.17 
UniRef50_Q011H2 Cluster: Predicted methyltransferase; n=2; Ostre...    39   0.17 
UniRef50_UPI0000384628 Cluster: COG0212: 5-formyltetrahydrofolat...    39   0.22 
UniRef50_Q0TWV8 Cluster: Predicted protein; n=1; Phaeosphaeria n...    39   0.22 
UniRef50_Q2FMV3 Cluster: 5-formyltetrahydrofolate cyclo-ligase; ...    39   0.22 
UniRef50_UPI00006CBD0D Cluster: 5-formyltetrahydrofolate cyclo-l...    38   0.29 
UniRef50_Q67Q66 Cluster: 5-formyltetrahydrofolate cyclo-ligase; ...    38   0.29 
UniRef50_A4J8I3 Cluster: 5-formyltetrahydrofolate cyclo-ligase; ...    38   0.29 
UniRef50_A0Y9S2 Cluster: 5-formyltetrahydrofolate cyclo-ligase f...    38   0.29 
UniRef50_Q81LX0 Cluster: 5-formyltetrahydrofolate cyclo-ligase f...    38   0.38 
UniRef50_Q3SFD5 Cluster: 5-formyltetrahydrofolate cyclo-ligase f...    38   0.38 
UniRef50_A6VUD0 Cluster: 5-formyltetrahydrofolate cyclo-ligase; ...    38   0.38 
UniRef50_A6QH93 Cluster: 5-formyltetrahydrofolate cyclo-ligase; ...    38   0.38 
UniRef50_A1IE08 Cluster: 5-formyltetrahydrofolate cyclo-ligase f...    38   0.38 
UniRef50_Q7VRG0 Cluster: Ligase;5-formyltetrahydrofolate cycloli...    38   0.51 
UniRef50_Q3AS61 Cluster: 5-formyltetrahydrofolate cyclo-ligase, ...    38   0.51 
UniRef50_A5P2B9 Cluster: 5-formyltetrahydrofolate cyclo-ligase; ...    38   0.51 
UniRef50_A1HT82 Cluster: 5-formyltetrahydrofolate cyclo-ligase; ...    38   0.51 
UniRef50_A0V3Q2 Cluster: 5-formyltetrahydrofolate cyclo-ligase; ...    38   0.51 
UniRef50_Q1DNE6 Cluster: Putative uncharacterized protein; n=2; ...    38   0.51 
UniRef50_Q7NBA0 Cluster: Putative uncharacterized protein; n=1; ...    37   0.67 
UniRef50_Q73P08 Cluster: 5-formyltetrahydrofolate cyclo-ligase f...    37   0.67 
UniRef50_Q5PAS2 Cluster: 5-formyltetrahydrofolate cyclo-ligase; ...    37   0.67 
UniRef50_Q2G6W2 Cluster: 5-formyltetrahydrofolate cyclo-ligase p...    37   0.67 
UniRef50_A4B8C7 Cluster: 5-formyltetrahydrofolate cyclo-ligase; ...    37   0.67 
UniRef50_A1S972 Cluster: 5-formyltetrahydrofolate cyclo-ligase f...    37   0.67 
UniRef50_A1BG38 Cluster: 5-formyltetrahydrofolate cyclo-ligase; ...    37   0.67 
UniRef50_Q8RF22 Cluster: 5-formyltetrahydrofolate cyclo-ligase; ...    37   0.88 
UniRef50_Q44SK2 Cluster: 5-formyltetrahydrofolate cyclo-ligase; ...    37   0.88 
UniRef50_Q2BL70 Cluster: Putative uncharacterized protein; n=1; ...    37   0.88 
UniRef50_Q1VME8 Cluster: 5-formyltetrahydrofolate cyclo-ligase; ...    37   0.88 
UniRef50_Q1FEZ7 Cluster: 5-formyltetrahydrofolate cyclo-ligase; ...    37   0.88 
UniRef50_Q0KWG0 Cluster: 5-formyltetrahydrofolate cyclo-ligase; ...    37   0.88 
UniRef50_A7HUZ2 Cluster: 5-formyltetrahydrofolate cyclo-ligase; ...    37   0.88 
UniRef50_A7DEJ5 Cluster: 5-formyltetrahydrofolate cyclo-ligase; ...    37   0.88 
UniRef50_P40099 Cluster: 5-formyltetrahydrofolate cyclo-ligase; ...    37   0.88 
UniRef50_Q8DC92 Cluster: 5-formyltetrahydrofolate cyclo-ligase; ...    36   1.2  
UniRef50_Q5QVB4 Cluster: 5-formyltetrahydrofolate cyclo-ligase f...    36   1.2  
UniRef50_Q0EWY4 Cluster: 5-formyltetrahydrofolate cyclo-ligase f...    36   1.2  
UniRef50_A4B9S4 Cluster: Putative carbon-nitrogen ligase; n=1; R...    36   1.2  
UniRef50_A3VP85 Cluster: 5-formyltetrahydrofolate cyclo-ligase; ...    36   1.2  
UniRef50_A0NJT9 Cluster: 5-formyltetrahydrofolate cyclo-ligase; ...    36   1.2  
UniRef50_Q4P9A6 Cluster: Putative uncharacterized protein; n=1; ...    36   1.2  
UniRef50_Q38VZ7 Cluster: 5-formyltetrahydrofolate cyclo-ligase; ...    36   1.5  
UniRef50_Q3B454 Cluster: 5-formyltetrahydrofolate cyclo-ligase, ...    36   2.0  
UniRef50_Q2J5Q1 Cluster: 5-formyltetrahydrofolate cyclo-ligase; ...    36   2.0  
UniRef50_A6BE49 Cluster: Putative uncharacterized protein; n=1; ...    36   2.0  
UniRef50_A4TWG6 Cluster: 5-formyltetrahydrofolate cyclo-ligase; ...    36   2.0  
UniRef50_Q75BE9 Cluster: ADL385Cp; n=1; Eremothecium gossypii|Re...    36   2.0  
UniRef50_Q2B5W6 Cluster: Possible 5-formyltetrahydrofolate cyclo...    35   2.7  
UniRef50_A7B2U8 Cluster: Putative uncharacterized protein; n=1; ...    35   2.7  
UniRef50_A6L8H7 Cluster: Putative 5-formyltetrahydrofolate cyclo...    35   2.7  
UniRef50_A6DB91 Cluster: 5-formyltetrahydrofolate cyclo-ligase; ...    35   2.7  
UniRef50_Q2ADA7 Cluster: 5-formyltetrahydrofolate cyclo-ligase; ...    35   3.6  
UniRef50_Q1LSJ3 Cluster: 5-formyltetrahydrofolate cyclo-ligase f...    35   3.6  
UniRef50_Q1GFD0 Cluster: 5-formyltetrahydrofolate cyclo-ligase; ...    35   3.6  
UniRef50_Q0BZ02 Cluster: 5-formyltetrahydrofolate cyclo-ligase f...    35   3.6  
UniRef50_A6DHI6 Cluster: Putative uncharacterized protein; n=1; ...    35   3.6  
UniRef50_A5CEL8 Cluster: 5-Formyltetrahydrofolate cyclo-ligase; ...    35   3.6  
UniRef50_A4SEK3 Cluster: 5-formyltetrahydrofolate cyclo-ligase; ...    35   3.6  
UniRef50_A4F7U0 Cluster: 5-formyltetrahydrofolate cyclo-ligase; ...    35   3.6  
UniRef50_A3MYI1 Cluster: Putative uncharacterized protein; n=1; ...    35   3.6  
UniRef50_A4RB99 Cluster: Putative uncharacterized protein; n=2; ...    35   3.6  
UniRef50_A7DNA8 Cluster: 5-formyltetrahydrofolate cyclo-ligase; ...    35   3.6  
UniRef50_Q89ZW3 Cluster: Putative 5-formyltetrahydrofolate cyclo...    34   4.7  
UniRef50_Q6F1L6 Cluster: 5-formyltetrahydrofolate cyclo-ligase f...    34   4.7  
UniRef50_Q5ZXY7 Cluster: 5-formyltetrahydrofolate cyclo-ligase; ...    34   4.7  
UniRef50_Q0VL96 Cluster: 5-formyltetrahydrofolate cyclo-ligase f...    34   4.7  
UniRef50_Q0A5K9 Cluster: 5-formyltetrahydrofolate cyclo-ligase; ...    34   4.7  
UniRef50_A5ZYS6 Cluster: Putative uncharacterized protein; n=3; ...    34   4.7  
UniRef50_A4XKH5 Cluster: 5-formyltetrahydrofolate cyclo-ligase; ...    34   4.7  
UniRef50_A4ABX0 Cluster: 5-formyltetrahydrofolate cyclo-ligase f...    34   4.7  
UniRef50_A1CDT2 Cluster: 5-formyltetrahydrofolate cyclo-ligase, ...    34   4.7  
UniRef50_Q9Z7E3 Cluster: Formyltetrahydrofolate Cycloligase; n=4...    34   6.2  
UniRef50_Q2NB11 Cluster: Possible 5-formyltetrahydrofolate cyclo...    34   6.2  
UniRef50_A7H9A8 Cluster: 5-formyltetrahydrofolate cyclo-ligase; ...    34   6.2  
UniRef50_A3V9L4 Cluster: 5-formyltetrahydrofolate cyclo-ligase f...    34   6.2  
UniRef50_A3UGX7 Cluster: 5-formyltetrahydrofolate cyclo-ligase; ...    34   6.2  
UniRef50_A1KWH4 Cluster: Putative uncharacterized protein; n=4; ...    34   6.2  
UniRef50_A0NNE7 Cluster: Putative uncharacterized protein; n=1; ...    34   6.2  
UniRef50_Q4JBH0 Cluster: 5-formyltetrahydrofolate cyclo-ligase; ...    34   6.2  
UniRef50_Q8N3X1 Cluster: Formin-binding protein 4; n=28; Eumetaz...    34   6.2  
UniRef50_Q31NN9 Cluster: Putative uncharacterized protein; n=2; ...    33   8.2  
UniRef50_Q2SN29 Cluster: 5-formyltetrahydrofolate cyclo-ligase; ...    33   8.2  
UniRef50_Q7D907 Cluster: 5-formyltetrahydrofolate cyclo-ligase-r...    33   8.2  
UniRef50_A4BS87 Cluster: 5-formyltetrahydrofolate cyclo-ligase; ...    33   8.2  
UniRef50_A4A1P3 Cluster: Putative uncharacterized protein; n=1; ...    33   8.2  
UniRef50_A3K0D8 Cluster: 5-formyltetrahydrofolate cyclo-ligase f...    33   8.2  
UniRef50_A2U6F2 Cluster: 5-formyltetrahydrofolate cyclo-ligase p...    33   8.2  
UniRef50_A2RHQ0 Cluster: 5-formyltetrahydrofolate cyclo-ligase f...    33   8.2  
UniRef50_Q55ZD6 Cluster: Putative uncharacterized protein; n=1; ...    33   8.2  

>UniRef50_UPI0000D569A3 Cluster: PREDICTED: similar to
           5-formyltetrahydrofolate cyclo-ligase
           (5,10-methenyl-tetrahydrofolate synthetase)
           (Methenyl-THF synthetase) (MTHFS); n=1; Tribolium
           castaneum|Rep: PREDICTED: similar to
           5-formyltetrahydrofolate cyclo-ligase
           (5,10-methenyl-tetrahydrofolate synthetase)
           (Methenyl-THF synthetase) (MTHFS) - Tribolium castaneum
          Length = 197

 Score =  111 bits (267), Expect = 3e-23
 Identities = 56/130 (43%), Positives = 84/130 (64%), Gaps = 4/130 (3%)
 Frame = +2

Query: 137 KALLRNEIAAKIAALTNEEKKRQSQIVYEKVINHSWYKSSSRIALYMSTENEIDTAPLIK 316
           K  +R EI+ ++  LT+EEK+ QS+IV+EK++N   ++ S R++ Y+S +NEIDT P+++
Sbjct: 8   KEAVRREISERLKHLTSEEKQTQSKIVFEKLLNLPSFQKSKRVSTYLSIDNEIDTEPIVR 67

Query: 317 HIQARGAAAFVPQY----AGGRMRMLHLETGDEQTMPKTKHGISQHGKDQARDDALETGG 484
            I   G   FVP+Y    AG  M  +H    D +T+P T  GI Q G  + R+DAL+TGG
Sbjct: 68  KIFETGKECFVPRYRYSKAGMEMVKIH-SYQDWETLPVTSWGIKQPGLKEQREDALKTGG 126

Query: 485 LDLIIAPGGG 514
           LD ++ PG G
Sbjct: 127 LDFVVVPGVG 136



 Score = 65.3 bits (152), Expect = 2e-09
 Identities = 28/63 (44%), Positives = 40/63 (63%)
 Frame = +1

Query: 508 GWRFLXSGDRLGHGXGYYDKFITNLRLNPETAPKIVAVAFNCQVVDEVPTTEQDXKVXEV 687
           G  F   G RLGHG GYYD+++ +LR N +  P +V +AF  Q+ D++P TE D ++  V
Sbjct: 134 GVGFTAKGLRLGHGGGYYDRYMADLRKNQDVPPALVGLAFKEQICDDLPVTELDVQIDLV 193

Query: 688 XFP 696
            FP
Sbjct: 194 LFP 196


>UniRef50_P49914 Cluster: 5-formyltetrahydrofolate cyclo-ligase;
           n=16; Euteleostomi|Rep: 5-formyltetrahydrofolate
           cyclo-ligase - Homo sapiens (Human)
          Length = 203

 Score =  109 bits (261), Expect = 1e-22
 Identities = 56/138 (40%), Positives = 87/138 (63%), Gaps = 3/138 (2%)
 Frame = +2

Query: 110 MSPIKPNPAKALLRNEIAAKIAALTNEEKKRQSQIVYEKVINHSWYKSSSRIALYMSTEN 289
           M+    + AK  LR E+  ++ A++ EE+ RQS+++ +KVI HS Y+ S RI++++S ++
Sbjct: 1   MAAAAVSSAKRSLRGELKQRLRAMSAEERLRQSRVLSQKVIAHSEYQKSKRISIFLSMQD 60

Query: 290 EIDTAPLIKHIQARGAAAFVPQY--AGGRMRMLHLETGDE-QTMPKTKHGISQHGKDQAR 460
           EI+T  +IK I  RG   F+P+Y      M M+ +E+ +E   +PKT   I Q G+   R
Sbjct: 61  EIETEEIIKDIFQRGKICFIPRYRFQSNHMDMVRIESPEEISLLPKTSWNIPQPGEGDVR 120

Query: 461 DDALETGGLDLIIAPGGG 514
           ++AL TGGLDLI  PG G
Sbjct: 121 EEALSTGGLDLIFMPGLG 138



 Score = 51.6 bits (118), Expect = 3e-05
 Identities = 25/62 (40%), Positives = 34/62 (54%)
 Frame = +1

Query: 508 GWRFLXSGDRLGHGXGYYDKFITNLRLNPETAPKIVAVAFNCQVVDEVPTTEQDXKVXEV 687
           G  F   G+RLG G GYYD ++     + E  P  +A+AF  Q+  +VP  E D KV EV
Sbjct: 136 GLGFDKHGNRLGRGKGYYDAYLKRCLQHQEVKPYTLALAFKEQICLQVPVNENDMKVDEV 195

Query: 688 XF 693
            +
Sbjct: 196 LY 197


>UniRef50_A7SFC3 Cluster: Predicted protein; n=1; Nematostella
           vectensis|Rep: Predicted protein - Nematostella
           vectensis
          Length = 205

 Score =  100 bits (240), Expect = 5e-20
 Identities = 50/128 (39%), Positives = 80/128 (62%), Gaps = 1/128 (0%)
 Frame = +2

Query: 134 AKALLRNEIAAKIAALTNEEKKRQSQIVYEKVINHSWYKSSSRIALYMSTENEIDTAPLI 313
           AK LLR +I  +I A++ E K+++S ++ EK++    YKSS RI++Y+S  +E+ T  ++
Sbjct: 10  AKKLLRRQIKKRILAMSEEAKRKESAMITEKLLAMEEYKSSHRISVYLSMPSEVSTFDIL 69

Query: 314 KHIQARGAAAFVPQYAGGRMRMLHLET-GDEQTMPKTKHGISQHGKDQARDDALETGGLD 490
           + I       ++P+Y G +M ML L +  D Q++P T   I Q   D  R++AL TGGLD
Sbjct: 70  RDIFNSNKKCYIPRYIGHQMDMLRLHSLEDMQSLPLTPWNIHQPADDDIREEALNTGGLD 129

Query: 491 LIIAPGGG 514
           +I+ PG G
Sbjct: 130 VILVPGLG 137



 Score = 51.6 bits (118), Expect = 3e-05
 Identities = 24/62 (38%), Positives = 33/62 (53%)
 Frame = +1

Query: 508 GWRFLXSGDRLGHGXGYYDKFITNLRLNPETAPKIVAVAFNCQVVDEVPTTEQDXKVXEV 687
           G  F  +G RLG G GYYD +I          P ++ +AF+ Q+ D+VP TE D  +  V
Sbjct: 135 GLGFSKNGQRLGRGKGYYDNYIQKCIELCHKKPHLIGLAFSTQMYDQVPVTENDMTLDHV 194

Query: 688 XF 693
            F
Sbjct: 195 VF 196


>UniRef50_P80405 Cluster: 5-formyltetrahydrofolate cyclo-ligase;
           n=12; Euteleostomi|Rep: 5-formyltetrahydrofolate
           cyclo-ligase - Oryctolagus cuniculus (Rabbit)
          Length = 201

 Score = 97.5 bits (232), Expect = 4e-19
 Identities = 51/130 (39%), Positives = 79/130 (60%), Gaps = 3/130 (2%)
 Frame = +2

Query: 134 AKALLRNEIAAKIAALTNEEKKRQSQIVYEKVINHSWYKSSSRIALYMSTENEIDTAPLI 313
           AK  LR E+  ++ A++ EE+ R  +++ +KVI H  Y+ S RI++++S  +EI+T  +I
Sbjct: 9   AKRSLRAELKQRLRAISAEERLRCQRLLTQKVIAHRQYQKSQRISIFLSMPDEIETEEII 68

Query: 314 KHIQARGAAAFVPQY--AGGRMRMLHLETGDE-QTMPKTKHGISQHGKDQARDDALETGG 484
           K I  +G   F+P+Y      M M+ L + DE  ++PKT   I Q  +   R++AL TGG
Sbjct: 69  KDIFQQGKVCFIPRYRLQSNHMDMVKLASADEISSLPKTSWNIHQPSESDTREEALATGG 128

Query: 485 LDLIIAPGGG 514
           LDLI  PG G
Sbjct: 129 LDLIFMPGLG 138



 Score = 47.2 bits (107), Expect = 6e-04
 Identities = 22/62 (35%), Positives = 32/62 (51%)
 Frame = +1

Query: 508 GWRFLXSGDRLGHGXGYYDKFITNLRLNPETAPKIVAVAFNCQVVDEVPTTEQDXKVXEV 687
           G  F  +G+RLG G GYYD ++          P  +A+AF  Q+  +VP  + D  V EV
Sbjct: 136 GLGFDRNGNRLGRGRGYYDTYLQRCLQQQGAKPYTIALAFREQICPQVPVDDTDVSVDEV 195

Query: 688 XF 693
            +
Sbjct: 196 LY 197


>UniRef50_Q16S54 Cluster: 5-formyltetrahydrofolate cyclo-ligase;
           n=3; Culicidae|Rep: 5-formyltetrahydrofolate
           cyclo-ligase - Aedes aegypti (Yellowfever mosquito)
          Length = 208

 Score = 86.6 bits (205), Expect = 8e-16
 Identities = 49/131 (37%), Positives = 75/131 (57%), Gaps = 2/131 (1%)
 Frame = +2

Query: 128 NPAKALLRNEIAAKIAALTNEEKKRQSQIVYEKVINHSWYKSSSRIALYMSTENEIDTAP 307
           NPAK  LR ++   ++ +++  +  QS+I+  KV    +Y  S RI +Y+STE E++T P
Sbjct: 6   NPAKVALRQQLKTVMSNMSSTARITQSKIIANKVQQLPFYHDSQRICIYLSTEREVNTVP 65

Query: 308 LIKHIQARGAAAFVPQYAGGRMRMLHL-ETGDEQTMPKTKHGISQ-HGKDQARDDALETG 481
           L++ +  R    FVP Y    MRM+ + +  D   +P T   I Q +  D +R+D L T 
Sbjct: 66  LLQDMFHRSKEVFVPTYNRTAMRMVKINDMVDYDRLPTTSWNIKQPNFGDNSREDCLAT- 124

Query: 482 GLDLIIAPGGG 514
           GLD+II PG G
Sbjct: 125 GLDMIILPGVG 135



 Score = 44.8 bits (101), Expect = 0.003
 Identities = 27/70 (38%), Positives = 37/70 (52%), Gaps = 7/70 (10%)
 Frame = +1

Query: 508 GWRFLXSGDRLGHGXGYYDKFITN-LRLNPETAPK----IVAVAFNCQVV--DEVPTTEQ 666
           G  F  SG RLGHG GYYD+F+    +  P  +      +V VAF  Q+V  D++P  E 
Sbjct: 133 GVGFTRSGHRLGHGGGYYDRFLLEYFKKFPNASDNRKTYLVGVAFREQIVPEDQLPIAEH 192

Query: 667 DXKVXEVXFP 696
           D  +  V +P
Sbjct: 193 DFPLDMVIWP 202


>UniRef50_Q9W1R6 Cluster: CG11079-PA, isoform A; n=6; Diptera|Rep:
           CG11079-PA, isoform A - Drosophila melanogaster (Fruit
           fly)
          Length = 318

 Score = 86.2 bits (204), Expect = 1e-15
 Identities = 46/129 (35%), Positives = 71/129 (55%), Gaps = 2/129 (1%)
 Frame = +2

Query: 128 NPAKALLRNEIAAKIAALTNEEKKRQSQIVYEKVINHSWYKSSSRIALYMSTENEIDTAP 307
           N  K  LR  +   +  +  E   RQSQ V  KV+    ++ + R+++Y+ST +E+DT  
Sbjct: 124 NTLKVALRKRMKDALKGIDAEAIARQSQAVTAKVLQSEIFRQAQRVSIYLSTASELDTTA 183

Query: 308 LIKHIQARGAAAFVPQYAGGRMRMLHLETGDE-QTMPKTKHGISQHGKDQARDDALETG- 481
           L+  +       FVP Y G RM+M+ L   +E +++P TK  I Q    +AR+DA+  G 
Sbjct: 184 LLSEMFRLEKMVFVPTYEGSRMKMVRLRGMEEYESLPLTKWNIKQPDFKEAREDAMTNGH 243

Query: 482 GLDLIIAPG 508
           G+DL I PG
Sbjct: 244 GIDLFIVPG 252



 Score = 41.9 bits (94), Expect = 0.023
 Identities = 22/63 (34%), Positives = 34/63 (53%), Gaps = 3/63 (4%)
 Frame = +1

Query: 508 GWRFLXSGDRLGHGXGYYDKFI-TNLRLNPETAPKIVAVAFNCQVV--DEVPTTEQDXKV 678
           G  F   G R+GHG GYYDKF+  +    P     ++A++ N Q+V  +E+P    D ++
Sbjct: 252 GVAFTRCGARMGHGMGYYDKFLKQHAEKYPHKKISLMALSLNEQIVSNEELPMESHDVRL 311

Query: 679 XEV 687
             V
Sbjct: 312 HSV 314


>UniRef50_Q9XWE6 Cluster: Putative 5-formyltetrahydrofolate
           cyclo-ligase; n=2; Caenorhabditis|Rep: Putative
           5-formyltetrahydrofolate cyclo-ligase - Caenorhabditis
           elegans
          Length = 206

 Score = 82.2 bits (194), Expect = 2e-14
 Identities = 47/136 (34%), Positives = 71/136 (52%), Gaps = 3/136 (2%)
 Frame = +2

Query: 110 MSPIKPNPAKALLRNEIAAKIAALTNEEKKRQSQIVYEKVINHSWYKSSSRIALYMSTEN 289
           MS IK    K+ LR  +   +  ++ EE +RQ++ V+EK+I   W++ S R+++Y+ST  
Sbjct: 1   MSAIKE--VKSELRQFMKTLLGKISKEETQRQTEAVFEKIIESKWFQESKRLSVYVSTSG 58

Query: 290 EIDTAPLIKHIQARGAAAFVPQYAGGRMRMLHLETGDE---QTMPKTKHGISQHGKDQAR 460
           EI T  +I+     G   F+PQ+  G   M  +   D+     +P T  GI Q       
Sbjct: 59  EIQTDSIIQKALEMGKEVFIPQFTKGSTAMDMVRVPDQTAFDNLPSTLWGIRQPEPKWKW 118

Query: 461 DDALETGGLDLIIAPG 508
               ETG LDLI+APG
Sbjct: 119 QSYHETGPLDLILAPG 134



 Score = 50.8 bits (116), Expect = 5e-05
 Identities = 24/63 (38%), Positives = 37/63 (58%), Gaps = 1/63 (1%)
 Frame = +1

Query: 508 GWRFLXSGDRLGHGXGYYDKFI-TNLRLNPETAPKIVAVAFNCQVVDEVPTTEQDXKVXE 684
           G  F   G R GHG GYYD+F  T+ +  PE +PK + +A   Q++  +P +E D ++ E
Sbjct: 134 GVAFSPYGLRCGHGKGYYDRFFSTHHKHFPENSPKKIGLALREQIIGTIPISETDVELDE 193

Query: 685 VXF 693
           V +
Sbjct: 194 VIY 196


>UniRef50_UPI0000E47106 Cluster: PREDICTED: hypothetical protein;
           n=1; Strongylocentrotus purpuratus|Rep: PREDICTED:
           hypothetical protein - Strongylocentrotus purpuratus
          Length = 161

 Score = 79.0 bits (186), Expect = 2e-13
 Identities = 38/97 (39%), Positives = 62/97 (63%), Gaps = 2/97 (2%)
 Frame = +2

Query: 230 INHSWYKSSSRIALYMSTENE-IDTAPLIKHIQARGAAAFVPQYAGGRMRMLHLET-GDE 403
           + H  Y+ S RI++Y++ + E +DT  +++ + ++    +VPQY G +M M+ + +  D 
Sbjct: 1   MEHPAYQKSQRISVYLAMKKEEVDTDGILRKMFSQNKLCYVPQYIGPKMNMMKMSSMEDY 60

Query: 404 QTMPKTKHGISQHGKDQARDDALETGGLDLIIAPGGG 514
           + +P+TK  I Q   D  R+DAL+TGGLDLII PG G
Sbjct: 61  EALPETKWKIKQPADDDVREDALKTGGLDLIIIPGLG 97



 Score = 43.6 bits (98), Expect = 0.008
 Identities = 21/62 (33%), Positives = 29/62 (46%)
 Frame = +1

Query: 508 GWRFLXSGDRLGHGXGYYDKFITNLRLNPETAPKIVAVAFNCQVVDEVPTTEQDXKVXEV 687
           G  F   G RLG G GYYD +           P  +A+AF  Q+ + +P TE D  +  V
Sbjct: 95  GLGFSKEGHRLGRGKGYYDIYQNRCVEETGVKPVTIALAFKEQICESIPITENDVTIDYV 154

Query: 688 XF 693
            +
Sbjct: 155 LY 156


>UniRef50_UPI0001553191 Cluster: PREDICTED: hypothetical protein;
           n=1; Mus musculus|Rep: PREDICTED: hypothetical protein -
           Mus musculus
          Length = 86

 Score = 56.4 bits (130), Expect = 1e-06
 Identities = 25/64 (39%), Positives = 46/64 (71%)
 Frame = +2

Query: 110 MSPIKPNPAKALLRNEIAAKIAALTNEEKKRQSQIVYEKVINHSWYKSSSRIALYMSTEN 289
           M+ +  N AK  LR E+  ++ AL+ EE+ RQS ++ +KVI H+ Y++S RI++++S ++
Sbjct: 1   MAAVTVNSAKRGLRAELKQRLRALSAEERLRQSLLLTQKVIAHNQYQNSKRISIFLSMQD 60

Query: 290 EIDT 301
           E++T
Sbjct: 61  EVET 64


>UniRef50_A0L5J2 Cluster: 5-formyltetrahydrofolate cyclo-ligase;
           n=1; Magnetococcus sp. MC-1|Rep:
           5-formyltetrahydrofolate cyclo-ligase - Magnetococcus
           sp. (strain MC-1)
          Length = 196

 Score = 55.6 bits (128), Expect = 2e-06
 Identities = 31/123 (25%), Positives = 57/123 (46%)
 Frame = +2

Query: 137 KALLRNEIAAKIAALTNEEKKRQSQIVYEKVINHSWYKSSSRIALYMSTENEIDTAPLIK 316
           K  LR  + A   AL    +   +      +++H+W   + R+ALY +   E+D APL+ 
Sbjct: 6   KEALRKTLLAWRGALDPAWRASANAAAVAHLLSHAWLGQAERVALYCAIRGELDPAPLLA 65

Query: 317 HIQARGAAAFVPQYAGGRMRMLHLETGDEQTMPKTKHGISQHGKDQARDDALETGGLDLI 496
            +   G   ++P+   G  ++        +   +   GI Q G D+A+   +E G +DL+
Sbjct: 66  PLWQMGKILYLPRLEAGASQIRFARHQQGEVWQRGPFGIPQPGPDRAQ---IEPGAVDLM 122

Query: 497 IAP 505
           + P
Sbjct: 123 LVP 125


>UniRef50_Q18VM6 Cluster: 5-formyltetrahydrofolate cyclo-ligase;
           n=2; Desulfitobacterium hafniense|Rep:
           5-formyltetrahydrofolate cyclo-ligase -
           Desulfitobacterium hafniense (strain DCB-2)
          Length = 194

 Score = 55.2 bits (127), Expect = 2e-06
 Identities = 28/57 (49%), Positives = 36/57 (63%)
 Frame = +1

Query: 508 GWRFLXSGDRLGHGXGYYDKFITNLRLNPETAPKIVAVAFNCQVVDEVPTTEQDXKV 678
           G  F   G+RLG+G GYYD+F   +R   E  PKI A+AF+CQ+VD +P    D KV
Sbjct: 126 GAAFDGQGNRLGYGGGYYDRFFERVR---EGTPKI-ALAFHCQIVDRIPVEVYDKKV 178



 Score = 37.9 bits (84), Expect = 0.38
 Identities = 21/75 (28%), Positives = 39/75 (52%)
 Frame = +2

Query: 137 KALLRNEIAAKIAALTNEEKKRQSQIVYEKVINHSWYKSSSRIALYMSTENEIDTAPLIK 316
           K LLR  + +  +ALT EE+  +SQ +   V     ++ +  I L+M+  +E++T  L +
Sbjct: 5   KRLLREHVLSLRSALTPEERASKSQRIRAIVTQTREFQEAGTIMLFMNFRDEVETTELAQ 64

Query: 317 HIQARGAAAFVPQYA 361
            +   G    +P+ A
Sbjct: 65  KVLDLGKRLVLPRCA 79


>UniRef50_A5DWB9 Cluster: Putative uncharacterized protein; n=1;
           Lodderomyces elongisporus NRRL YB-4239|Rep: Putative
           uncharacterized protein - Lodderomyces elongisporus
           (Yeast) (Saccharomyces elongisporus)
          Length = 216

 Score = 53.6 bits (123), Expect = 7e-06
 Identities = 37/136 (27%), Positives = 74/136 (54%), Gaps = 11/136 (8%)
 Frame = +2

Query: 134 AKALLRNEIAAKIAALTNEEKKRQSQIVYEKVINHSWYKSSSRIALYMSTEN-EIDTAPL 310
           AK LLR +I  K+A ++ E   +QSQ + ++++    +K++ ++AL+M+  + E+ T P+
Sbjct: 10  AKKLLRVKIKHKLATISQESLSQQSQEILDRLVQSPIFKNAQKVALFMNMPDLEVKTLPI 69

Query: 311 IKHIQARGAAAF--------VPQYAGGRMRMLHLETGDE--QTMPKTKHGISQHGKDQAR 460
           I+    +    +        VP      + ML++ T  +  +  P+ K+ + +  + +  
Sbjct: 70  IQECYNQKKEVYLPRCNTISVPNRKRNYLSMLNVPTFQDILELRPQGKYQLLEPIEGK-- 127

Query: 461 DDALETGGLDLIIAPG 508
            DAL++G LDLI+ PG
Sbjct: 128 -DALDSGDLDLILMPG 142



 Score = 39.1 bits (87), Expect = 0.17
 Identities = 19/65 (29%), Positives = 32/65 (49%), Gaps = 2/65 (3%)
 Frame = +1

Query: 508 GWRFLXSGDRLGHGXGYYDKFITNLRLNPETAPKIVAVAFNCQVVDE--VPTTEQDXKVX 681
           G  F    +RLGHG G+YD+++   +   E  P +V +A   Q+     +P    D K+ 
Sbjct: 142 GVAFNQQRERLGHGAGFYDEYLYTYKTKWEHLPLLVGLALEEQITTNGLIPVELHDFKLD 201

Query: 682 EVXFP 696
           ++  P
Sbjct: 202 QIITP 206


>UniRef50_Q97K31 Cluster: 5-formyltetrahydrofolate cyclo-ligase;
           n=1; Clostridium acetobutylicum|Rep:
           5-formyltetrahydrofolate cyclo-ligase - Clostridium
           acetobutylicum
          Length = 182

 Score = 53.2 bits (122), Expect = 1e-05
 Identities = 34/125 (27%), Positives = 62/125 (49%)
 Frame = +2

Query: 134 AKALLRNEIAAKIAALTNEEKKRQSQIVYEKVINHSWYKSSSRIALYMSTENEIDTAPLI 313
           +K  LR  +  K  +L  + K  +  ++Y KVIN   YKS++ I +++S ++E+DT  +I
Sbjct: 4   SKKELRKNMVLKRDSLEPDLKSIKDNMIYNKVINSIQYKSANNIFVFVSYKSEVDTHNII 63

Query: 314 KHIQARGAAAFVPQYAGGRMRMLHLETGDEQTMPKTKHGISQHGKDQARDDALETGGLDL 493
           +   A G   FVP+       M   E      + K+ +GI     +    + +E   ++L
Sbjct: 64  RTAIADGKKVFVPKVISKEKGMEAAEIRGFFDLEKSAYGI----LEPKSSNYIEPESIEL 119

Query: 494 IIAPG 508
           ++ PG
Sbjct: 120 LLVPG 124



 Score = 36.7 bits (81), Expect = 0.88
 Identities = 20/60 (33%), Positives = 36/60 (60%)
 Frame = +1

Query: 508 GWRFLXSGDRLGHGXGYYDKFITNLRLNPETAPKIVAVAFNCQVVDEVPTTEQDXKVXEV 687
           G  F  SG R+G+G G+YD++++   L  ++A K V + ++ QV+D+V     D  V ++
Sbjct: 124 GLAFDESGGRIGYGGGFYDRYMS---LLDKSAVK-VGICYDFQVIDKVIMNINDVPVDKI 179


>UniRef50_Q97NE8 Cluster: 5-formyltetrahydrofolate cyclo-ligase
           family protein; n=29; Streptococcus|Rep:
           5-formyltetrahydrofolate cyclo-ligase family protein -
           Streptococcus pneumoniae
          Length = 179

 Score = 52.8 bits (121), Expect = 1e-05
 Identities = 34/125 (27%), Positives = 63/125 (50%), Gaps = 1/125 (0%)
 Frame = +2

Query: 137 KALLRNEIAAKIAALTNEEKKRQSQIVYEKVINHSWYKSSSRIALYMSTENEIDTAPLIK 316
           K+ LR ++  ++ A++ E+K+   Q + E+++ H +Y+ +  IA Y+S  +E  T  LI+
Sbjct: 2   KSELRKQVLHEMKAISQEQKQAIDQALTERLLQHPFYQEAKVIATYLSFSHEFQTQELIE 61

Query: 317 HIQARGAAAFVPQ-YAGGRMRMLHLETGDEQTMPKTKHGISQHGKDQARDDALETGGLDL 493
                G    +P+ Y  GRM  +     D Q + KT   + +   D    + ++   +DL
Sbjct: 62  QALKDGKKVLIPKTYPKGRMDFV---VYDPQQLVKTFFALLELQGDL---EVVDASQIDL 115

Query: 494 IIAPG 508
           I  PG
Sbjct: 116 IHVPG 120



 Score = 34.7 bits (76), Expect = 3.6
 Identities = 18/60 (30%), Positives = 31/60 (51%)
 Frame = +1

Query: 508 GWRFLXSGDRLGHGXGYYDKFITNLRLNPETAPKIVAVAFNCQVVDEVPTTEQDXKVXEV 687
           G  F   G R+G+G GYYD+++ +       + + ++  + CQ+ D +P    D  V EV
Sbjct: 120 GLAFTTKGYRIGYGGGYYDRYLEHF------SGRTLSTIYPCQIQDFIP-ENHDIPVQEV 172


>UniRef50_A3LUI4 Cluster: 5,10-methenyltetrahydrofolate synthetase;
           n=3; Saccharomycetales|Rep:
           5,10-methenyltetrahydrofolate synthetase - Pichia
           stipitis (Yeast)
          Length = 207

 Score = 52.4 bits (120), Expect = 2e-05
 Identities = 40/143 (27%), Positives = 72/143 (50%), Gaps = 10/143 (6%)
 Frame = +2

Query: 110 MSPIKPNPAKALLRNEIAAKIAALTNEEKKRQSQIVYEKVINHSWYKSSSRIALYMS-TE 286
           MS +K   AK  LR +I   + A++ E  + QS  +++K++ H  ++ +++IALYM+  +
Sbjct: 1   MSSLKQ--AKTQLRRQIKESLRAISQESLQTQSNDIHKKLLGHPVFQKATKIALYMNMPD 58

Query: 287 NEIDTAPLIKHIQARGAAAFVP----QYAGGRMRMLHLETGDEQTMPKTKHGISQHGKDQ 454
           +E+ T  +I      G   ++P    +   GR +  HL      +    K  +   GK Q
Sbjct: 59  SEVKTDAIIHSCYQMGKQVYLPRCKTEVVEGR-KNCHLVMLRVPSYEDVK-ALKPQGKYQ 116

Query: 455 ARD-----DALETGGLDLIIAPG 508
             +     DA++ G LD++I PG
Sbjct: 117 LLEPIEGVDAMDEGDLDVVIVPG 139



 Score = 40.7 bits (91), Expect = 0.054
 Identities = 17/51 (33%), Positives = 27/51 (52%)
 Frame = +1

Query: 517 FLXSGDRLGHGXGYYDKFITNLRLNPETAPKIVAVAFNCQVVDEVPTTEQD 669
           F  +  R+GHG G+YD+FI          P ++ +  + Q V+ +PT E D
Sbjct: 142 FSTTKQRMGHGAGFYDEFIKFYNSKHNRRPYLIGLGLHQQFVNSLPTEEHD 192


>UniRef50_A6LQ49 Cluster: 5-formyltetrahydrofolate cyclo-ligase;
           n=1; Clostridium beijerinckii NCIMB 8052|Rep:
           5-formyltetrahydrofolate cyclo-ligase - Clostridium
           beijerinckii NCIMB 8052
          Length = 196

 Score = 52.0 bits (119), Expect = 2e-05
 Identities = 34/124 (27%), Positives = 57/124 (45%)
 Frame = +2

Query: 137 KALLRNEIAAKIAALTNEEKKRQSQIVYEKVINHSWYKSSSRIALYMSTENEIDTAPLIK 316
           K +LR EI  K   +   EK++  + + E V +  +YK +  I +Y+S + EI+T   IK
Sbjct: 7   KKILRKEILDKRKKIDVTEKEKMDERILETVYSSEYYKLAKNIFVYISFDTEINTRDFIK 66

Query: 317 HIQARGAAAFVPQYAGGRMRMLHLETGDEQTMPKTKHGISQHGKDQARDDALETGGLDLI 496
                    +VP+       M  +E      + ++ +GI +       D  ++   LDLI
Sbjct: 67  ESLNNNKRIYVPRTEIKTRLMDAVEIKSLDNLSESSYGIPE---PSINDPYIDPNELDLI 123

Query: 497 IAPG 508
           I PG
Sbjct: 124 IVPG 127



 Score = 41.1 bits (92), Expect = 0.041
 Identities = 21/59 (35%), Positives = 37/59 (62%), Gaps = 2/59 (3%)
 Frame = +1

Query: 508 GWRFLXSGDRLGHGXGYYDKFITNLRLNPETAPKI--VAVAFNCQVVDEVPTTEQDXKV 678
           G  F   G R+G+G G+YD++    ++N +   +I  +A+A++ QV+D+VPT+  D  V
Sbjct: 127 GVAFDKRGGRVGYGAGFYDRYFK--KVNKDNIKRITKLALAYDFQVLDKVPTSYHDVPV 183


>UniRef50_Q4AQ84 Cluster: 5-formyltetrahydrofolate cyclo-ligase;
           n=1; Chlorobium phaeobacteroides BS1|Rep:
           5-formyltetrahydrofolate cyclo-ligase - Chlorobium
           phaeobacteroides BS1
          Length = 194

 Score = 51.6 bits (118), Expect = 3e-05
 Identities = 26/50 (52%), Positives = 32/50 (64%)
 Frame = +1

Query: 529 GDRLGHGXGYYDKFITNLRLNPETAPKIVAVAFNCQVVDEVPTTEQDXKV 678
           G RLG+G GYYD+FI  LRL   T P  +AVAF+ Q+V  VP    D K+
Sbjct: 134 GRRLGYGKGYYDRFIAGLRLQGAT-PFTLAVAFSFQLVSHVPEDPWDEKI 182



 Score = 45.2 bits (102), Expect = 0.003
 Identities = 27/95 (28%), Positives = 49/95 (51%), Gaps = 3/95 (3%)
 Frame = +2

Query: 134 AKALLRNEIAAKIAALTNEEKKRQSQIVYEKVINHSWYKSSSRIALYMSTEN--EIDTAP 307
           +K  +R E   + A++ +EE +  S ++ E V     ++ +  + +Y+S     E+DTAP
Sbjct: 6   SKERIRRECRERRASMDSEEWRSASSLIAENVAGIQEFREARTVMMYLSMNERREVDTAP 65

Query: 308 LIKHIQARG-AAAFVPQYAGGRMRMLHLETGDEQT 409
           LI    + G ++ +VP   G  + M+    GDE T
Sbjct: 66  LISLCASFGNSSLYVPVTRGETLCMVPFNEGDEVT 100


>UniRef50_A5DQN3 Cluster: Putative uncharacterized protein; n=1;
           Pichia guilliermondii|Rep: Putative uncharacterized
           protein - Pichia guilliermondii (Yeast) (Candida
           guilliermondii)
          Length = 214

 Score = 51.2 bits (117), Expect = 4e-05
 Identities = 23/54 (42%), Positives = 33/54 (61%)
 Frame = +1

Query: 508 GWRFLXSGDRLGHGXGYYDKFITNLRLNPETAPKIVAVAFNCQVVDEVPTTEQD 669
           G  F  SG RLGHG G+YD+F+T  + +    P +V +A   Q+VD++P  E D
Sbjct: 138 GMAFTKSGRRLGHGAGFYDEFLTVYQSHFARVPYLVGLALLEQIVDDIPHEEHD 191



 Score = 41.9 bits (94), Expect = 0.023
 Identities = 35/137 (25%), Positives = 67/137 (48%), Gaps = 12/137 (8%)
 Frame = +2

Query: 134 AKALLRNEIAAKIAALTNEEKKRQSQIVYEKVINHSWYKSSSRIALYMSTEN-EIDTAPL 310
           AK  LR+ +   ++ +T+     QS +V   ++    ++S+  + +YM+    E+ T  +
Sbjct: 5   AKRDLRSRVRKVLSGVTSGSLHGQSTVVCRTLLESEQFRSAKSVGVYMNMPTMEVQTESI 64

Query: 311 IKHIQARGAAAFVPQYAG-----GR----MRMLHLET-GDEQTM-PKTKHGISQHGKDQA 457
           IK    +  A F+P+ +      GR    M M+H+ + GD   + P+ K+ + +  +   
Sbjct: 65  IKACFDQQKAVFLPKCSSNARCEGRKKNYMSMIHVPSLGDVHNLEPQGKYRLLEPTEGT- 123

Query: 458 RDDALETGGLDLIIAPG 508
             +   T GLDL+I PG
Sbjct: 124 --EVFNTAGLDLLILPG 138


>UniRef50_Q65HC6 Cluster: YqgN; n=1; Bacillus licheniformis ATCC
           14580|Rep: YqgN - Bacillus licheniformis (strain DSM 13
           / ATCC 14580)
          Length = 190

 Score = 49.6 bits (113), Expect = 1e-04
 Identities = 28/124 (22%), Positives = 58/124 (46%)
 Frame = +2

Query: 137 KALLRNEIAAKIAALTNEEKKRQSQIVYEKVINHSWYKSSSRIALYMSTENEIDTAPLIK 316
           K  LR+E+  ++A +  +E   +++ ++ K+     +K +S IAL +S   E+ T P+I+
Sbjct: 2   KRSLRSEVRKRLANMPEQEFHLKAEAIHRKLFQSKQWKKASVIALTVSRNREVPTKPIIE 61

Query: 317 HIQARGAAAFVPQYAGGRMRMLHLETGDEQTMPKTKHGISQHGKDQARDDALETGGLDLI 496
             +  G    +P+      +M      DE  +     G+ +      + + +E   +D I
Sbjct: 62  QARLEGKTVCIPKCMPETKKMHFRSYQDESDLEVVYFGLQE--PIVHKTERMEPEDIDFI 119

Query: 497 IAPG 508
           + PG
Sbjct: 120 LVPG 123



 Score = 40.3 bits (90), Expect = 0.072
 Identities = 20/53 (37%), Positives = 30/53 (56%)
 Frame = +1

Query: 529 GDRLGHGXGYYDKFITNLRLNPETAPKIVAVAFNCQVVDEVPTTEQDXKVXEV 687
           G R+G+G GYYD+++       +TA    ++AF CQV+  VP    D  V +V
Sbjct: 130 GYRIGYGGGYYDRYLAG--FTKDTA----SLAFECQVIGHVPNEPHDIPVKQV 176


>UniRef50_Q21EV7 Cluster: 5-formyltetrahydrofolate cyclo-ligase;
           n=1; Saccharophagus degradans 2-40|Rep:
           5-formyltetrahydrofolate cyclo-ligase - Saccharophagus
           degradans (strain 2-40 / ATCC 43961 / DSM 17024)
          Length = 194

 Score = 49.6 bits (113), Expect = 1e-04
 Identities = 32/123 (26%), Positives = 61/123 (49%)
 Frame = +2

Query: 137 KALLRNEIAAKIAALTNEEKKRQSQIVYEKVINHSWYKSSSRIALYMSTENEIDTAPLIK 316
           K  LR  + AK  ALT  ++   S+ V   +   S Y+ ++ IA Y++ + E+D  P +K
Sbjct: 3   KDTLRQTMRAKRNALTPSQQAFASEQVATHLAQSSDYQQATHIAFYLACDGELDLTPALK 62

Query: 317 HIQARGAAAFVPQYAGGRMRMLHLETGDEQTMPKTKHGISQHGKDQARDDALETGGLDLI 496
              A   A ++P  A  R ++      +  ++   ++GI++   D   +  ++   LDL+
Sbjct: 63  QALADNKACYLPVIAPNR-QLRFRRYNEGCSLVTNRYGIAEPSAD---NPEIQPNRLDLV 118

Query: 497 IAP 505
           +AP
Sbjct: 119 LAP 121


>UniRef50_Q83F82 Cluster: 5-formyltetrahydrofolate cyclo-ligase
           family protein; n=3; Coxiella burnetii|Rep:
           5-formyltetrahydrofolate cyclo-ligase family protein -
           Coxiella burnetii
          Length = 197

 Score = 48.8 bits (111), Expect = 2e-04
 Identities = 34/125 (27%), Positives = 61/125 (48%), Gaps = 1/125 (0%)
 Frame = +2

Query: 134 AKALLRNEIAAKIAALTNEEKKRQSQIVYEKVINHSWYKSSSRIALYMSTENEIDTAPLI 313
           +K  LR+++  +   L+ +EK + S+I+ +K++  S +KSS R+A Y+S + E+D    +
Sbjct: 6   SKKQLRDQLRQRRNELSFQEKNKASEIICKKIMGLSIFKSSERLAFYLSHDGEVDIRIAL 65

Query: 314 KHIQARGAAAFVPQYAGGRMRMLHLETGD-EQTMPKTKHGISQHGKDQARDDALETGGLD 490
                   A F+P         L   +   +  + K + GI +   D  R+  + T  LD
Sbjct: 66  SKALEVKKACFLPLLHCTLDHHLDFYSYHLKSELIKNRFGIGE--PDPTRETPIATKELD 123

Query: 491 LIIAP 505
           LI  P
Sbjct: 124 LIFLP 128



 Score = 41.1 bits (92), Expect = 0.041
 Identities = 18/57 (31%), Positives = 31/57 (54%)
 Frame = +1

Query: 517 FLXSGDRLGHGXGYYDKFITNLRLNPETAPKIVAVAFNCQVVDEVPTTEQDXKVXEV 687
           F   G+RLG G GYYD+ +  L+ +    PK++ VA+  Q ++ +   + D  +  V
Sbjct: 132 FDKDGNRLGRGAGYYDRALAFLKDSNAQKPKLIGVAYEFQKINSITAEKWDIPLNSV 188


>UniRef50_Q7URX2 Cluster: 5-formyltetrahydrofolate cyclo-ligase;
           n=1; Pirellula sp.|Rep: 5-formyltetrahydrofolate
           cyclo-ligase - Rhodopirellula baltica
          Length = 205

 Score = 48.0 bits (109), Expect = 4e-04
 Identities = 23/60 (38%), Positives = 34/60 (56%)
 Frame = +1

Query: 508 GWRFLXSGDRLGHGXGYYDKFITNLRLNPETAPKIVAVAFNCQVVDEVPTTEQDXKVXEV 687
           G  F   G R+GHG GYYDK + N+R    +  +++ +AF CQ+V  VP    D ++  V
Sbjct: 136 GVAFDRHGGRVGHGKGYYDKLLGNVR----SDTRLIGLAFECQMVGAVPVQAHDIRMDMV 191


>UniRef50_Q3AE50 Cluster: 5-formyltetrahydrofolate cyclo-ligase
           family protein; n=1; Carboxydothermus hydrogenoformans
           Z-2901|Rep: 5-formyltetrahydrofolate cyclo-ligase family
           protein - Carboxydothermus hydrogenoformans (strain
           Z-2901 / DSM 6008)
          Length = 192

 Score = 48.0 bits (109), Expect = 4e-04
 Identities = 24/54 (44%), Positives = 34/54 (62%)
 Frame = +1

Query: 508 GWRFLXSGDRLGHGXGYYDKFITNLRLNPETAPKIVAVAFNCQVVDEVPTTEQD 669
           G  F   G+RLG+G G+YD+F+ NL    + A K VA+AF  Q+V ++PT   D
Sbjct: 125 GVAFDLKGNRLGYGAGFYDRFLPNL----QPAVKKVALAFELQIVPKIPTGPHD 174


>UniRef50_A6EYV6 Cluster: 5-formyltetrahydrofolate cyclo-ligase
           family protein; n=2; Gammaproteobacteria|Rep:
           5-formyltetrahydrofolate cyclo-ligase family protein -
           Marinobacter algicola DG893
          Length = 216

 Score = 47.6 bits (108), Expect = 5e-04
 Identities = 21/53 (39%), Positives = 30/53 (56%)
 Frame = +1

Query: 529 GDRLGHGXGYYDKFITNLRLNPETAPKIVAVAFNCQVVDEVPTTEQDXKVXEV 687
           G RLG G G+YD+     R+ P  APK++ +A +CQ V E+P    D  +  V
Sbjct: 149 GGRLGMGGGFYDRTFAFTRIRPRLAPKLIGLAHDCQKVLELPLEPWDIPLHSV 201


>UniRef50_Q6CAN2 Cluster: Similar to sp|P40099 Saccharomyces
           cerevisiae YER183c FAU1 similarity to human 5; n=1;
           Yarrowia lipolytica|Rep: Similar to sp|P40099
           Saccharomyces cerevisiae YER183c FAU1 similarity to
           human 5 - Yarrowia lipolytica (Candida lipolytica)
          Length = 212

 Score = 47.6 bits (108), Expect = 5e-04
 Identities = 40/142 (28%), Positives = 70/142 (49%), Gaps = 16/142 (11%)
 Frame = +2

Query: 131 PAKALLRNEIAAKIAALTNEEKKRQSQIVYEKVINHSWYKSSSRIALYMSTEN-EIDTAP 307
           PAK  LR  IA ++A ++ +  ++QS      +   + YKS+  IA YM+ ++ E++T  
Sbjct: 4   PAKQQLRKLIAQRVADVSKDSIQKQSLATTAALRTLNEYKSAQNIAFYMNMDSGELETMD 63

Query: 308 LIKHIQARGAAAFVPQY-------------AGGRMRMLHL-ETGDEQTM-PKTKHGISQH 442
           +I++        F+P+                  +RML + +  D Q + P+  + + + 
Sbjct: 64  MIRNAFEDKKRVFLPRIEKLADTADKIHPCQKSELRMLEIVDFKDVQNLQPRGPYKLKEP 123

Query: 443 GKDQARDDALETGGLDLIIAPG 508
            KD    D LE+GGL LI+ PG
Sbjct: 124 TKD--AKDVLESGGLGLIVLPG 143



 Score = 39.9 bits (89), Expect = 0.095
 Identities = 20/45 (44%), Positives = 26/45 (57%)
 Frame = +1

Query: 535 RLGHGXGYYDKFITNLRLNPETAPKIVAVAFNCQVVDEVPTTEQD 669
           RLGHG G+YD +I +        PK+V V    Q+VDE+P  E D
Sbjct: 152 RLGHGVGFYDAYI-HKHEKLLGVPKLVGVCLREQLVDELPLEEHD 195


>UniRef50_A3CVT9 Cluster: 5-formyltetrahydrofolate cyclo-ligase;
           n=1; Methanoculleus marisnigri JR1|Rep:
           5-formyltetrahydrofolate cyclo-ligase - Methanoculleus
           marisnigri (strain ATCC 35101 / DSM 1498 / JR1)
          Length = 203

 Score = 47.6 bits (108), Expect = 5e-04
 Identities = 22/54 (40%), Positives = 32/54 (59%)
 Frame = +1

Query: 517 FLXSGDRLGHGXGYYDKFITNLRLNPETAPKIVAVAFNCQVVDEVPTTEQDXKV 678
           F   G+RLG+G GYYD+F     L+    PK + +AF+CQ  + +P  E D K+
Sbjct: 138 FDAEGNRLGYGAGYYDRF-----LHRYPHPKKIGIAFSCQQAERIPADENDVKM 186


>UniRef50_Q9KD02 Cluster: 5-formyltetrahydrofolate cyclo-ligase;
           n=1; Bacillus halodurans|Rep: 5-formyltetrahydrofolate
           cyclo-ligase - Bacillus halodurans
          Length = 186

 Score = 46.8 bits (106), Expect = 8e-04
 Identities = 23/57 (40%), Positives = 37/57 (64%)
 Frame = +1

Query: 508 GWRFLXSGDRLGHGXGYYDKFITNLRLNPETAPKIVAVAFNCQVVDEVPTTEQDXKV 678
           G  F   G+RLG+G GYYD+F+ + +       K +A+A++ Q+V+ VPT E+D +V
Sbjct: 125 GVAFDQKGNRLGYGGGYYDRFLHSYK------GKTIALAYSQQLVESVPTDERDERV 175


>UniRef50_Q896J3 Cluster: 5-formyltetrahydrofolate cyclo-ligase;
           n=6; Clostridium|Rep: 5-formyltetrahydrofolate
           cyclo-ligase - Clostridium tetani
          Length = 183

 Score = 46.8 bits (106), Expect = 8e-04
 Identities = 24/60 (40%), Positives = 36/60 (60%)
 Frame = +1

Query: 508 GWRFLXSGDRLGHGXGYYDKFITNLRLNPETAPKIVAVAFNCQVVDEVPTTEQDXKVXEV 687
           G  F   G RLG+G G+YDKF   L+   +  PK V +A++ Q+VD VP  E D ++ ++
Sbjct: 124 GLAFDNKGGRLGYGGGFYDKFFKRLK---KDTPK-VGLAYSFQIVDFVPMYEWDVRINDI 179



 Score = 37.9 bits (84), Expect = 0.38
 Identities = 27/124 (21%), Positives = 55/124 (44%)
 Frame = +2

Query: 137 KALLRNEIAAKIAALTNEEKKRQSQIVYEKVINHSWYKSSSRIALYMSTENEIDTAPLIK 316
           K  LR +   K   L+ ++       ++E+VI   +YK ++ I +++S ++E+ T  +IK
Sbjct: 4   KKELREKSMVKRDGLSKDKINEYDGNIFERVIESKYYKEANCIFIFVSYKSEVHTHEIIK 63

Query: 317 HIQARGAAAFVPQYAGGRMRMLHLETGDEQTMPKTKHGISQHGKDQARDDALETGGLDLI 496
                     VP+    +  M  +E      +   + GI +      + D +E   +D++
Sbjct: 64  RALKDNKRVCVPKIISLKDGMEVIEIKSFSELKPGEKGILEPVDFSRKVDPME---IDIV 120

Query: 497 IAPG 508
             PG
Sbjct: 121 FTPG 124


>UniRef50_Q041X5 Cluster: 5-formyltetrahydrofolate cyclo-ligase;
           n=2; Lactobacillus|Rep: 5-formyltetrahydrofolate
           cyclo-ligase - Lactobacillus gasseri (strain ATCC 33323
           / DSM 20243)
          Length = 195

 Score = 46.4 bits (105), Expect = 0.001
 Identities = 34/127 (26%), Positives = 61/127 (48%), Gaps = 2/127 (1%)
 Frame = +2

Query: 134 AKALLRNEIAAKIAALTNEEKK-RQSQIVYEKVINHSWYKSSSRIALYMSTENEIDTAPL 310
           +K  LR     K+    N ++K  + +I+ EK++  S    +  I + +S   E++TAP+
Sbjct: 15  SKKELRKLQIKKLTEFANSKQKLSEDKILKEKLLRSSLLTKAESIGISVSMPIEVNTAPI 74

Query: 311 IKHIQARGAAAFVPQYAGGRMRMLHLETGDEQT-MPKTKHGISQHGKDQARDDALETGGL 487
           I  +   G   ++P+      R +     D+ T + KTK G+ ++       +A+    L
Sbjct: 75  IASLWKMGKRVYIPRCL--PKRKMEFTLYDKNTILVKTKFGVLENHD----SEAIVNNNL 128

Query: 488 DLIIAPG 508
           DLII PG
Sbjct: 129 DLIIVPG 135


>UniRef50_Q1AWE3 Cluster: 5-formyltetrahydrofolate cyclo-ligase;
           n=1; Rubrobacter xylanophilus DSM 9941|Rep:
           5-formyltetrahydrofolate cyclo-ligase - Rubrobacter
           xylanophilus (strain DSM 9941 / NBRC 16129)
          Length = 196

 Score = 46.0 bits (104), Expect = 0.001
 Identities = 24/57 (42%), Positives = 29/57 (50%)
 Frame = +1

Query: 508 GWRFLXSGDRLGHGXGYYDKFITNLRLNPETAPKIVAVAFNCQVVDEVPTTEQDXKV 678
           G  F   G RLGHG GYYD+ +   R      P +VA AF  Q+V+ VP    D  V
Sbjct: 129 GVAFDRRGGRLGHGAGYYDRLLGGAR----RLPPLVAAAFEAQIVERVPMEPHDVPV 181


>UniRef50_A3EWC9 Cluster: 5-formyltetrahydrofolate cyclo-ligase;
           n=1; Leptospirillum sp. Group II UBA|Rep:
           5-formyltetrahydrofolate cyclo-ligase - Leptospirillum
           sp. Group II UBA
          Length = 206

 Score = 46.0 bits (104), Expect = 0.001
 Identities = 25/60 (41%), Positives = 35/60 (58%)
 Frame = +1

Query: 508 GWRFLXSGDRLGHGXGYYDKFITNLRLNPETAPKIVAVAFNCQVVDEVPTTEQDXKVXEV 687
           G  F   G R+G+G GYYD+ + N      TAP ++A+AF  Q+VD VP +E D  V  +
Sbjct: 138 GLGFDRRGGRIGYGRGYYDRLLRN-----TTAP-LIALAFQEQIVDRVPLSETDILVDTI 191


>UniRef50_A6CNU5 Cluster: Possible 5-formyltetrahydrofolate
           cyclo-ligase; n=1; Bacillus sp. SG-1|Rep: Possible
           5-formyltetrahydrofolate cyclo-ligase - Bacillus sp.
           SG-1
          Length = 187

 Score = 45.6 bits (103), Expect = 0.002
 Identities = 24/60 (40%), Positives = 35/60 (58%)
 Frame = +1

Query: 508 GWRFLXSGDRLGHGXGYYDKFITNLRLNPETAPKIVAVAFNCQVVDEVPTTEQDXKVXEV 687
           G  F+ SG RLG G GYYD+F+ N +         +++AF  Q+V+EVP  E D  V ++
Sbjct: 124 GLAFMNSGYRLGFGGGYYDRFLVNYQ------GSTLSLAFQEQLVEEVPVQEFDIPVDKI 177


>UniRef50_A7I701 Cluster: 5-formyltetrahydrofolate cyclo-ligase;
           n=1; Candidatus Methanoregula boonei 6A8|Rep:
           5-formyltetrahydrofolate cyclo-ligase - Methanoregula
           boonei (strain 6A8)
          Length = 188

 Score = 45.6 bits (103), Expect = 0.002
 Identities = 21/54 (38%), Positives = 32/54 (59%)
 Frame = +1

Query: 517 FLXSGDRLGHGXGYYDKFITNLRLNPETAPKIVAVAFNCQVVDEVPTTEQDXKV 678
           F  +G R+G+G GYYD+F+     NP+     + VAF CQ ++ +P  E D K+
Sbjct: 126 FDRTGGRIGYGAGYYDRFLAQ---NPDLVK--IGVAFGCQEMEHLPVDENDIKM 174


>UniRef50_A6VM34 Cluster: 5-formyltetrahydrofolate cyclo-ligase;
           n=3; Pasteurellaceae|Rep: 5-formyltetrahydrofolate
           cyclo-ligase - Actinobacillus succinogenes 130Z
          Length = 189

 Score = 45.2 bits (102), Expect = 0.003
 Identities = 31/96 (32%), Positives = 48/96 (50%), Gaps = 3/96 (3%)
 Frame = +2

Query: 137 KALLRNEIAAKIAALTNEEKKRQSQIVYEKVINHSWYKSSSRIALYMSTENEIDTAPLIK 316
           +A LR +I      LT  E+ R +Q V +K +N    + +  I LY+S + EI T PLI 
Sbjct: 8   RAQLRRQIRKTRQNLTALEQIRAAQTVTQKALNLIAQRHAEHIGLYLSFDGEISTRPLID 67

Query: 317 HIQARGAAAFVP---QYAGGRMRMLHLETGDEQTMP 415
            + A+    ++P    +  G M  LH  T + + MP
Sbjct: 68  ALWAQRKNVYLPVLHPFCKGYMLFLHY-TPETELMP 102



 Score = 35.1 bits (77), Expect = 2.7
 Identities = 19/57 (33%), Positives = 29/57 (50%)
 Frame = +1

Query: 517 FLXSGDRLGHGXGYYDKFITNLRLNPETAPKIVAVAFNCQVVDEVPTTEQDXKVXEV 687
           F   G+RLG G G+YD+ + +       A   V +A  CQ VDE+P    D  + ++
Sbjct: 133 FDKQGNRLGMGGGFYDRTLQDWHEKNFIA---VGLAHQCQQVDELPVENWDIPLFDI 186


>UniRef50_A6S3W0 Cluster: Putative uncharacterized protein; n=5;
           Pezizomycotina|Rep: Putative uncharacterized protein -
           Botryotinia fuckeliana B05.10
          Length = 246

 Score = 45.2 bits (102), Expect = 0.003
 Identities = 40/143 (27%), Positives = 65/143 (45%), Gaps = 18/143 (12%)
 Frame = +2

Query: 134 AKALLRNEIAAKIAALTNEEKKRQSQIVYEKVINHSWYKSSSRIALYMSTEN-EIDTAPL 310
           +K  LR  I   ++ +TNE    QS  V  ++IN   Y+ + RI +Y++    E+ T  +
Sbjct: 10  SKKELRLSIKKLLSTVTNESVHAQSAAVLHRLINFQPYQQAKRIGIYLAMPTGELQTDAI 69

Query: 311 IKHIQARGAAAFVP-----QYAG-----GRMRMLHLET-GDEQTMPKTKHGISQHGKDQA 457
           ++H    G   FVP      Y         M M+ L +  D + + +   GI     +  
Sbjct: 70  VRHALESGKQVFVPYLHKSSYQSPDTPRSVMDMVDLRSLADFEALKRDSWGIPTIPAETV 129

Query: 458 --RDDALET----GGLDLIIAPG 508
             R+  L+T    GGLD+I+ PG
Sbjct: 130 GERESILKTVSSKGGLDMILLPG 152


>UniRef50_A5Z6A8 Cluster: Putative uncharacterized protein; n=1;
           Eubacterium ventriosum ATCC 27560|Rep: Putative
           uncharacterized protein - Eubacterium ventriosum ATCC
           27560
          Length = 175

 Score = 44.8 bits (101), Expect = 0.003
 Identities = 20/60 (33%), Positives = 37/60 (61%)
 Frame = +1

Query: 508 GWRFLXSGDRLGHGXGYYDKFITNLRLNPETAPKIVAVAFNCQVVDEVPTTEQDXKVXEV 687
           G  F   G+RLG+G G+YD+F+ + ++        + VA++ Q+++ +PT E D K+ E+
Sbjct: 119 GVAFSKKGERLGYGGGFYDRFLEHHKV------YTIGVAYDFQIMNSLPTEEHDRKLNEI 172


>UniRef50_Q03Y24 Cluster: 5-formyltetrahydrofolate cyclo-ligase;
           n=1; Leuconostoc mesenteroides subsp. mesenteroides ATCC
           8293|Rep: 5-formyltetrahydrofolate cyclo-ligase -
           Leuconostoc mesenteroides subsp. mesenteroides (strain
           ATCC 8293 /NCDO 523)
          Length = 178

 Score = 44.4 bits (100), Expect = 0.004
 Identities = 22/62 (35%), Positives = 34/62 (54%)
 Frame = +1

Query: 508 GWRFLXSGDRLGHGXGYYDKFITNLRLNPETAPKIVAVAFNCQVVDEVPTTEQDXKVXEV 687
           G  F  SG RLG G GYYD+F+ +       A   ++VA + Q++D++PT   D  V  +
Sbjct: 121 GLAFTVSGKRLGFGAGYYDRFLEHY------AGHTISVALSTQLLDDLPTENHDQTVQRI 174

Query: 688 XF 693
            +
Sbjct: 175 LY 176



 Score = 37.5 bits (83), Expect = 0.51
 Identities = 31/124 (25%), Positives = 61/124 (49%)
 Frame = +2

Query: 137 KALLRNEIAAKIAALTNEEKKRQSQIVYEKVINHSWYKSSSRIALYMSTENEIDTAPLIK 316
           K+ LR +  A +A     ++KR+ + +Y  +     ++S+  IA+ +S E E++T+P+I 
Sbjct: 4   KSELRIQQKAALARENLMKRKREEEQLYALLFQTPEWQSADSIAVTLSMEFELNTSPIII 63

Query: 317 HIQARGAAAFVPQYAGGRMRMLHLETGDEQTMPKTKHGISQHGKDQARDDALETGGLDLI 496
               +     VP+    +M  + +   D  T  +T  G+  + ++   D+      LDL+
Sbjct: 64  KAWEKSKRVLVPKIINHKMIFVEI---DSNTRYQT--GM-LNIREPLIDNYQAVEQLDLV 117

Query: 497 IAPG 508
           I PG
Sbjct: 118 IVPG 121


>UniRef50_Q6AQJ8 Cluster: Probable 5-formyltetrahydrofolate
           cyclo-ligase; n=1; Desulfotalea psychrophila|Rep:
           Probable 5-formyltetrahydrofolate cyclo-ligase -
           Desulfotalea psychrophila
          Length = 191

 Score = 44.0 bits (99), Expect = 0.006
 Identities = 29/125 (23%), Positives = 62/125 (49%), Gaps = 3/125 (2%)
 Frame = +2

Query: 143 LLRNEIAAKIAALTNEEKKRQSQIVYEKVINHSWYKSSSRIALYMSTENEIDTAPLIKHI 322
           LLR E+  K   L++ E+  QS+   +K+ +  +   +  + +Y+S   E++T  L+  +
Sbjct: 4   LLRREVLIKRKNLSDAERFEQSKRAVQKLSD--FLAEAQTVFVYLSYNGEVETFELVDKL 61

Query: 323 QARGAAAFVPQYAGGRMRMLHLETGD---EQTMPKTKHGISQHGKDQARDDALETGGLDL 493
            ARG    +P  +    +++ +E  +      + +  +GISQ       +++L    +D+
Sbjct: 62  LARGFRVTIPWTSLVDKKIIPVEIFENNFRMLLEEGPYGISQPSSTYMEENSLLAEEIDV 121

Query: 494 IIAPG 508
           +I PG
Sbjct: 122 VICPG 126


>UniRef50_Q603N0 Cluster: 5-formyltetrahydrofolate cyclo-ligase
           family protein; n=1; Methylococcus capsulatus|Rep:
           5-formyltetrahydrofolate cyclo-ligase family protein -
           Methylococcus capsulatus
          Length = 221

 Score = 44.0 bits (99), Expect = 0.006
 Identities = 16/52 (30%), Positives = 32/52 (61%)
 Frame = +2

Query: 197 KRQSQIVYEKVINHSWYKSSSRIALYMSTENEIDTAPLIKHIQARGAAAFVP 352
           +R S ++  + I+  W   ++R+A Y+  + E+DT  L ++++ RG  AF+P
Sbjct: 45  RRTSLLIAGRCIDAGWLDGAARMAAYLPNDGEVDTTVLFEYLRERGRTAFIP 96



 Score = 33.9 bits (74), Expect = 6.2
 Identities = 17/48 (35%), Positives = 25/48 (52%), Gaps = 1/48 (2%)
 Frame = +1

Query: 529 GDRLGHGXGYYDK-FITNLRLNPETAPKIVAVAFNCQVVDEVPTTEQD 669
           G RLG G GYYD+ F   L      +P+++ +AF  Q V+ +     D
Sbjct: 151 GHRLGMGGGYYDRTFAFRLAEPARASPRLIGLAFEGQKVERLEARPWD 198


>UniRef50_Q1WUH7 Cluster: 5-formyltetrahydrofolate cyclo-ligase;
           n=1; Lactobacillus salivarius subsp. salivarius
           UCC118|Rep: 5-formyltetrahydrofolate cyclo-ligase -
           Lactobacillus salivarius subsp. salivarius (strain
           UCC118)
          Length = 182

 Score = 44.0 bits (99), Expect = 0.006
 Identities = 32/125 (25%), Positives = 62/125 (49%), Gaps = 1/125 (0%)
 Frame = +2

Query: 137 KALLRNEIAAKIAALTNE-EKKRQSQIVYEKVINHSWYKSSSRIALYMSTENEIDTAPLI 313
           K   +N+I  K+  L+   EKK     +Y+++   + ++ +  +A+ +S + E+DT P+I
Sbjct: 6   KEFRKNQIQ-KLQKLSKTWEKKLDELNLYKELFKTTEWEKADNVAITLSEDFELDTFPII 64

Query: 314 KHIQARGAAAFVPQYAGGRMRMLHLETGDEQTMPKTKHGISQHGKDQARDDALETGGLDL 493
              Q +     VP+    RM M  +E   +  + +TK G+     +   ++ +    +DL
Sbjct: 65  STAQQQNKKVLVPKTFPNRM-MEFVELTPDVKIVRTKFGV----LEPESENYVNKENIDL 119

Query: 494 IIAPG 508
           II PG
Sbjct: 120 IIVPG 124


>UniRef50_Q1MQA3 Cluster: 5-formyltetrahydrofolate cyclo-ligase;
           n=1; Lawsonia intracellularis PHE/MN1-00|Rep:
           5-formyltetrahydrofolate cyclo-ligase - Lawsonia
           intracellularis (strain PHE/MN1-00)
          Length = 193

 Score = 44.0 bits (99), Expect = 0.006
 Identities = 21/73 (28%), Positives = 38/73 (52%)
 Frame = +2

Query: 137 KALLRNEIAAKIAALTNEEKKRQSQIVYEKVINHSWYKSSSRIALYMSTENEIDTAPLIK 316
           K  +RN    +  AL++EE    S+I+  K+ N   ++ +  +ALY S +NE+ T  L++
Sbjct: 6   KDFVRNSCIIRRQALSSEEVHSASRIIAAKLFNDDVWRRARSVALYSSIKNEVSTESLLR 65

Query: 317 HIQARGAAAFVPQ 355
                G    +P+
Sbjct: 66  QAWQEGKQVLLPR 78


>UniRef50_A3IGL7 Cluster: 5-formyltetrahydrofolate cyclo-ligase;
           n=1; Bacillus sp. B14905|Rep: 5-formyltetrahydrofolate
           cyclo-ligase - Bacillus sp. B14905
          Length = 197

 Score = 44.0 bits (99), Expect = 0.006
 Identities = 21/73 (28%), Positives = 41/73 (56%)
 Frame = +2

Query: 137 KALLRNEIAAKIAALTNEEKKRQSQIVYEKVINHSWYKSSSRIALYMSTENEIDTAPLIK 316
           K  LRN++   +A + +E  +RQS+ V ++V+   +   ++ I + +S + E+DT  LI+
Sbjct: 3   KTTLRNKVRETLAIMNDEVYRRQSKAVVKRVLQEPYIIEANTIGITISNQPEVDTILLIE 62

Query: 317 HIQARGAAAFVPQ 355
            +   G    VP+
Sbjct: 63  ELWQLGKKVAVPK 75



 Score = 43.6 bits (98), Expect = 0.008
 Identities = 20/56 (35%), Positives = 34/56 (60%)
 Frame = +1

Query: 529 GDRLGHGXGYYDKFITNLRLNPETAPKIVAVAFNCQVVDEVPTTEQDXKVXEVXFP 696
           G R+G+G GYYD+++ N +       K++++ F+ Q+V+ VPT E D  V  +  P
Sbjct: 131 GYRIGYGGGYYDRYVLNYKKG-----KLMSLLFDEQIVNRVPTEEHDCPVDIIVTP 181


>UniRef50_Q3XWC2 Cluster: 5-formyltetrahydrofolate cyclo-ligase;
           n=1; Enterococcus faecium DO|Rep:
           5-formyltetrahydrofolate cyclo-ligase - Enterococcus
           faecium DO
          Length = 180

 Score = 43.6 bits (98), Expect = 0.008
 Identities = 30/125 (24%), Positives = 60/125 (48%), Gaps = 1/125 (0%)
 Frame = +2

Query: 137 KALLRNEIAAKIAALTNEEKKRQS-QIVYEKVINHSWYKSSSRIALYMSTENEIDTAPLI 313
           K  LR +   K+  L    KK++  Q +Y+++    ++KS+  I   +S E E+DT P+I
Sbjct: 5   KVRLRRKGIEKLKNLAKSGKKKEKEQRIYKQLFASEYWKSAKVIGTTLSNEFELDTQPVI 64

Query: 314 KHIQARGAAAFVPQYAGGRMRMLHLETGDEQTMPKTKHGISQHGKDQARDDALETGGLDL 493
           +  +       VP+    R +M   E  ++  + ++  G+ +   ++     +    +DL
Sbjct: 65  QRAEKEQKKIVVPKTLPKR-QMAFYEMDEQSVLVRSSFGVLEPQSEKLYLPEM----IDL 119

Query: 494 IIAPG 508
           +I PG
Sbjct: 120 LIVPG 124


>UniRef50_A5N8A1 Cluster: 5-formyltetrahydrofolate
           cyclo-ligase-related protein; n=1; Clostridium kluyveri
           DSM 555|Rep: 5-formyltetrahydrofolate
           cyclo-ligase-related protein - Clostridium kluyveri DSM
           555
          Length = 181

 Score = 43.6 bits (98), Expect = 0.008
 Identities = 21/54 (38%), Positives = 33/54 (61%)
 Frame = +1

Query: 508 GWRFLXSGDRLGHGXGYYDKFITNLRLNPETAPKIVAVAFNCQVVDEVPTTEQD 669
           G  F  SG R+G+G GYYD+F+  LR       K + +A++ Q++D+VP  + D
Sbjct: 123 GLAFDKSGGRVGYGGGYYDRFLKKLR----NDSKKIGLAYSFQILDKVPMGKYD 172


>UniRef50_A1SSJ1 Cluster: 5-formyltetrahydrofolate cyclo-ligase;
           n=3; Gammaproteobacteria|Rep: 5-formyltetrahydrofolate
           cyclo-ligase - Psychromonas ingrahamii (strain 37)
          Length = 196

 Score = 43.6 bits (98), Expect = 0.008
 Identities = 20/60 (33%), Positives = 32/60 (53%)
 Frame = +1

Query: 517 FLXSGDRLGHGXGYYDKFITNLRLNPETAPKIVAVAFNCQVVDEVPTTEQDXKVXEVXFP 696
           F   G+R+G G GYYD+ +       +T P  + +A +CQ V ++P  E D  + E+  P
Sbjct: 132 FDTQGNRIGMGGGYYDRMLAPW-FKDKTGPYPIGLAHDCQQVQQLPVEEWDVPLPEIITP 190



 Score = 43.2 bits (97), Expect = 0.010
 Identities = 28/121 (23%), Positives = 60/121 (49%), Gaps = 1/121 (0%)
 Frame = +2

Query: 146 LRNEIAAKIAALTNEEKKRQSQIVYEKVINHSWYKSSSRIALYMSTENEIDTAPLIKHIQ 325
           +R++I      L+  ++K+ +  ++ ++I HS  + + +I++ ++ + EIDT   ++   
Sbjct: 10  IRHQIRTARRDLSGLQQKQDADSLFSRLIKHSRVQQAGKISVTLAYDGEIDTLRFVEWCW 69

Query: 326 ARGAAAFVPQ-YAGGRMRMLHLETGDEQTMPKTKHGISQHGKDQARDDALETGGLDLIIA 502
            +    ++P  +   +  +L LE   +  M   +HGI +   +Q   DA     LDLI  
Sbjct: 70  QKNKKIYLPVIHPFNKGHLLFLEYTTKTEMVLNQHGIFEPKLNQL--DACPMKELDLIFT 127

Query: 503 P 505
           P
Sbjct: 128 P 128


>UniRef50_Q6FTS7 Cluster: Similar to sp|P40099 Saccharomyces
           cerevisiae YER183c FAU1; n=2; Saccharomycetales|Rep:
           Similar to sp|P40099 Saccharomyces cerevisiae YER183c
           FAU1 - Candida glabrata (Yeast) (Torulopsis glabrata)
          Length = 229

 Score = 43.6 bits (98), Expect = 0.008
 Identities = 19/55 (34%), Positives = 29/55 (52%), Gaps = 1/55 (1%)
 Frame = +1

Query: 508 GWRFLXSGDRLGHGXGYYDKFITNLRL-NPETAPKIVAVAFNCQVVDEVPTTEQD 669
           G  F     RLGHG GYYD F +  +L +    P ++ +A   Q+V+++P    D
Sbjct: 153 GVAFTSGCSRLGHGAGYYDDFFSRYKLQHSNQLPLLIGIALKQQIVEDIPMDAHD 207


>UniRef50_Q41FV0 Cluster: 5-formyltetrahydrofolate cyclo-ligase;
           n=1; Exiguobacterium sibiricum 255-15|Rep:
           5-formyltetrahydrofolate cyclo-ligase - Exiguobacterium
           sibiricum 255-15
          Length = 182

 Score = 43.2 bits (97), Expect = 0.010
 Identities = 34/124 (27%), Positives = 59/124 (47%)
 Frame = +2

Query: 137 KALLRNEIAAKIAALTNEEKKRQSQIVYEKVINHSWYKSSSRIALYMSTENEIDTAPLIK 316
           K  +R  I  ++  L N E+K   Q +Y+++     +K++  IA+ +S  NE  T P+I 
Sbjct: 3   KQEIRRWITDQLNRLENREQK--QQQIYDQLFELPEWKNAQSIAVTLSFRNECATDPIIL 60

Query: 317 HIQARGAAAFVPQYAGGRMRMLHLETGDEQTMPKTKHGISQHGKDQARDDALETGGLDLI 496
                G    +P+    +  M   E      + +TK GI +   DQA + +L +  +DL 
Sbjct: 61  KAWQLGKQVVIPKVI--QQEMKFFEYVPNSPLIETKMGI-REPDDQANEQSLRS--VDLC 115

Query: 497 IAPG 508
           + PG
Sbjct: 116 LVPG 119



 Score = 33.5 bits (73), Expect = 8.2
 Identities = 19/60 (31%), Positives = 30/60 (50%)
 Frame = +1

Query: 508 GWRFLXSGDRLGHGXGYYDKFITNLRLNPETAPKIVAVAFNCQVVDEVPTTEQDXKVXEV 687
           G  F  +G R+G G G+YD+ +T      +     VAV F+CQ+V +      D  V ++
Sbjct: 119 GRAFTRAGYRIGWGGGFYDRALT------DYPGHTVAVTFDCQLVSDFEVEPFDQPVQKI 172


>UniRef50_A6NRP0 Cluster: Putative uncharacterized protein; n=1;
           Bacteroides capillosus ATCC 29799|Rep: Putative
           uncharacterized protein - Bacteroides capillosus ATCC
           29799
          Length = 186

 Score = 43.2 bits (97), Expect = 0.010
 Identities = 28/124 (22%), Positives = 60/124 (48%)
 Frame = +2

Query: 137 KALLRNEIAAKIAALTNEEKKRQSQIVYEKVINHSWYKSSSRIALYMSTENEIDTAPLIK 316
           KA LR  + A+++A++ EE++    I++ + +      ++ R+ L+     E DTA LI 
Sbjct: 10  KAALRRVVRARLSAMSPEEREESDGILFRRFLALPEVAAADRVLLFYGMGAEPDTARLIP 69

Query: 317 HIQARGAAAFVPQYAGGRMRMLHLETGDEQTMPKTKHGISQHGKDQARDDALETGGLDLI 496
            +   G    +P+   G   +      ++  + + ++G+ + G+D      +    +DLI
Sbjct: 70  VLLDMGKQVLLPRCLPGH-GLEARRVAEKSVLIRHRYGMLEPGED---CPVVPREAIDLI 125

Query: 497 IAPG 508
           + PG
Sbjct: 126 LVPG 129


>UniRef50_A4A119 Cluster: 5-formyltetrahydrofolate cyclo-ligase;
           n=1; Blastopirellula marina DSM 3645|Rep:
           5-formyltetrahydrofolate cyclo-ligase - Blastopirellula
           marina DSM 3645
          Length = 197

 Score = 43.2 bits (97), Expect = 0.010
 Identities = 20/57 (35%), Positives = 32/57 (56%)
 Frame = +1

Query: 508 GWRFLXSGDRLGHGXGYYDKFITNLRLNPETAPKIVAVAFNCQVVDEVPTTEQDXKV 678
           G  F   G+RLG+G GY+D+ ++ +R    T     A+AF CQ+  ++PT   D  +
Sbjct: 129 GVAFDLHGNRLGYGKGYFDRLLSEMRPQAVTC----ALAFECQLTAQIPTEPHDLPI 181


>UniRef50_A3DEZ8 Cluster: 5-formyltetrahydrofolate cyclo-ligase;
           n=1; Clostridium thermocellum ATCC 27405|Rep:
           5-formyltetrahydrofolate cyclo-ligase - Clostridium
           thermocellum (strain ATCC 27405 / DSM 1237)
          Length = 191

 Score = 43.2 bits (97), Expect = 0.010
 Identities = 34/127 (26%), Positives = 60/127 (47%), Gaps = 3/127 (2%)
 Frame = +2

Query: 137 KALLRNEIAAKIAALTNEEKKRQSQIVYEKVINHSWYKSSSRIALYMSTENEIDTAPLIK 316
           K  LR E       L+ EE   +S+++ EK+I+   + +S  +  YM  +NE+ T  LI+
Sbjct: 4   KRELRKEALNIRKGLSEEEIIEKSKLITEKLISLDGFYNSKCVMAYMDFKNEVMTRFLIE 63

Query: 317 HIQARGAAAFVP--QYAGGRMRMLHLE-TGDEQTMPKTKHGISQHGKDQARDDALETGGL 487
           H    G    +P      G  ++   E T  E  +    +GI +  K+ +R   ++   +
Sbjct: 64  HCLNLGKIVALPLIDCVDGVKKIFPYELTNQEGCLKPGTYGILEPVKEFSR--KIDPKDI 121

Query: 488 DLIIAPG 508
           DL++ PG
Sbjct: 122 DLVVVPG 128



 Score = 37.5 bits (83), Expect = 0.51
 Identities = 21/54 (38%), Positives = 29/54 (53%)
 Frame = +1

Query: 508 GWRFLXSGDRLGHGXGYYDKFITNLRLNPETAPKIVAVAFNCQVVDEVPTTEQD 669
           G  F   G R+G+G GYYD F+  +R   +   KI  +AF+ QV   +P  E D
Sbjct: 128 GVAFDVKGGRIGYGAGYYDIFLREVR---KDCLKI-GIAFDIQVFPSIPKEEHD 177


>UniRef50_A1U687 Cluster: 5-formyltetrahydrofolate cyclo-ligase;
           n=4; Gammaproteobacteria|Rep: 5-formyltetrahydrofolate
           cyclo-ligase - Marinobacter aquaeolei (strain ATCC
           700491 / DSM 11845 / VT8)(Marinobacter
           hydrocarbonoclasticus (strain DSM 11845))
          Length = 211

 Score = 43.2 bits (97), Expect = 0.010
 Identities = 19/51 (37%), Positives = 30/51 (58%)
 Frame = +1

Query: 517 FLXSGDRLGHGXGYYDKFITNLRLNPETAPKIVAVAFNCQVVDEVPTTEQD 669
           F  +G RLG G G+YD+     R+ P  APK++ +A + Q V+++P    D
Sbjct: 144 FDETGGRLGMGGGFYDRTFAFSRIRPGMAPKLIGLAHDFQRVEQLPVEPWD 194


>UniRef50_Q6CX89 Cluster: Similarities with sp|P40099 Saccharomyces
           cerevisiae YER183c FAU1 singleton; n=1; Kluyveromyces
           lactis|Rep: Similarities with sp|P40099 Saccharomyces
           cerevisiae YER183c FAU1 singleton - Kluyveromyces lactis
           (Yeast) (Candida sphaerica)
          Length = 291

 Score = 43.2 bits (97), Expect = 0.010
 Identities = 20/51 (39%), Positives = 29/51 (56%)
 Frame = +1

Query: 526 SGDRLGHGXGYYDKFITNLRLNPETAPKIVAVAFNCQVVDEVPTTEQDXKV 678
           +G R+GHG GYYD +I+         P +V +A   Q+VD+VP  + D  V
Sbjct: 227 NGARMGHGAGYYDDYISRHIHYTGKKPLLVGLALEEQLVDDVPLEQHDYTV 277


>UniRef50_Q14L13 Cluster: Putative 5-formyltetrahydrofolate
           cyclo-ligase protein; n=1; Spiroplasma citri|Rep:
           Putative 5-formyltetrahydrofolate cyclo-ligase protein -
           Spiroplasma citri
          Length = 183

 Score = 42.7 bits (96), Expect = 0.013
 Identities = 20/84 (23%), Positives = 44/84 (52%)
 Frame = +2

Query: 137 KALLRNEIAAKIAALTNEEKKRQSQIVYEKVINHSWYKSSSRIALYMSTENEIDTAPLIK 316
           K  +R E     + +++E ++++   +++    H   ++S  IALY S +NE++T  +IK
Sbjct: 6   KQEIRQEKLLARSKISSELRQQKETKIFDTFFQHPGVQNSKTIALYYSIKNEVNTLLIIK 65

Query: 317 HIQARGAAAFVPQYAGGRMRMLHL 388
            + A      +P+  G  ++  H+
Sbjct: 66  RLFALKVNILLPRMDGNNLKFYHI 89


>UniRef50_Q03G82 Cluster: 5-formyltetrahydrofolate cyclo-ligase;
           n=1; Pediococcus pentosaceus ATCC 25745|Rep:
           5-formyltetrahydrofolate cyclo-ligase - Pediococcus
           pentosaceus (strain ATCC 25745 / 183-1w)
          Length = 187

 Score = 42.3 bits (95), Expect = 0.018
 Identities = 30/124 (24%), Positives = 55/124 (44%)
 Frame = +2

Query: 137 KALLRNEIAAKIAALTNEEKKRQSQIVYEKVINHSWYKSSSRIALYMSTENEIDTAPLIK 316
           K + R     ++  +    K+ +  ++ E   +    K++ ++A+ MS   E+DTAP+I+
Sbjct: 3   KNIFRQTQIKRLNQIDITSKRAKEALILESFFDQHEVKNARKLAITMSHGFELDTAPIIQ 62

Query: 317 HIQARGAAAFVPQYAGGRMRMLHLETGDEQTMPKTKHGISQHGKDQARDDALETGGLDLI 496
            +   G   +VP+    R         +    PK +  +   G +  R +A     LDLI
Sbjct: 63  RLIENGKCVYVPRTLPERQMEFVEYNLNTPMQPKFQGILEPVGGNVVRPEA-----LDLI 117

Query: 497 IAPG 508
           I PG
Sbjct: 118 IVPG 121


>UniRef50_A4AI88 Cluster: 5-formyltetrahydrofolate
           cyclo-ligase-related protein; n=3; Actinobacteria
           (class)|Rep: 5-formyltetrahydrofolate
           cyclo-ligase-related protein - marine actinobacterium
           PHSC20C1
          Length = 196

 Score = 42.3 bits (95), Expect = 0.018
 Identities = 23/57 (40%), Positives = 31/57 (54%)
 Frame = +1

Query: 526 SGDRLGHGXGYYDKFITNLRLNPETAPKIVAVAFNCQVVDEVPTTEQDXKVXEVXFP 696
           +G R+G G GY+DK + ++    ET P I AV F  + VD VPT   D  V  +  P
Sbjct: 134 TGMRMGWGRGYFDKTLGSM----ETKPPIYAVIFESEYVDAVPTELHDQPVNGIVTP 186


>UniRef50_Q4K404 Cluster: 5-formyltetrahydrofolate cyclo-ligase
           family protein; n=16; Pseudomonadaceae|Rep:
           5-formyltetrahydrofolate cyclo-ligase family protein -
           Pseudomonas fluorescens (strain Pf-5 / ATCC BAA-477)
          Length = 230

 Score = 41.9 bits (94), Expect = 0.023
 Identities = 31/130 (23%), Positives = 64/130 (49%), Gaps = 2/130 (1%)
 Frame = +2

Query: 122 KPNP-AKALLRNEIAAKIAALTNEEKKRQSQIVYEKVINHSWYKSSSRIALYMSTENEID 298
           +P P ++  LR  +     AL+  E+++ +  +Y ++     ++ +  ++LY+ T+ EID
Sbjct: 32  EPAPLSRPQLRRMLRKARRALSPAEQRQAALGLYRQLAQDPVFRRARHLSLYLPTDGEID 91

Query: 299 TAPLIKHIQARGAAAFVPQY-AGGRMRMLHLETGDEQTMPKTKHGISQHGKDQARDDALE 475
              L++  Q RG A ++P   A  R +M+       +T+   +  I +   + AR    +
Sbjct: 92  PRLLLRAAQRRGKATYLPVLSAWPRTKMVFQRVLPGETLRPNRFRILEPRVNCARQ--RK 149

Query: 476 TGGLDLIIAP 505
              LDL++ P
Sbjct: 150 VWALDLVLLP 159



 Score = 33.5 bits (73), Expect = 8.2
 Identities = 18/52 (34%), Positives = 26/52 (50%), Gaps = 1/52 (1%)
 Frame = +1

Query: 517 FLXSGDRLGHGXGYYDKFITNL-RLNPETAPKIVAVAFNCQVVDEVPTTEQD 669
           F   G RLG G G+YD+ +  L R      PK++ +A  CQ V ++     D
Sbjct: 163 FDEEGGRLGMGGGFYDRSLAYLARRQNWRKPKLLGLAHECQKVGKLDQASWD 214


>UniRef50_A6TVJ5 Cluster: 5-formyltetrahydrofolate cyclo-ligase;
           n=2; Clostridiaceae|Rep: 5-formyltetrahydrofolate
           cyclo-ligase - Alkaliphilus metalliredigens QYMF
          Length = 192

 Score = 41.9 bits (94), Expect = 0.023
 Identities = 31/125 (24%), Positives = 58/125 (46%), Gaps = 1/125 (0%)
 Frame = +2

Query: 137 KALLRNEIAAKIAALTNEEKKRQSQIVYEKVINHSWYKSSSRIALYMSTENEIDTAPLIK 316
           K  LR ++ A+   L++   + +SQ V   + N S YK +  + LY+S   E+ T  +I+
Sbjct: 2   KNTLRKQLLAQREILSSVHMETKSQQVRSSLFNFSPYKKAQHVMLYVSFGKEVITRGIIQ 61

Query: 317 HIQARGAAAFVPQYAGGRMRMLHLETGD-EQTMPKTKHGISQHGKDQARDDALETGGLDL 493
            +  +    F+P        ++  E  D ++ +     G+ +  K+  R   ++   LD 
Sbjct: 62  DLLDQNKRVFIPVCVPKTKELIISELLDFDEDLEIGHFGVLEPKKEALR--PVDPKILDF 119

Query: 494 IIAPG 508
           II PG
Sbjct: 120 IIVPG 124



 Score = 41.5 bits (93), Expect = 0.031
 Identities = 23/57 (40%), Positives = 33/57 (57%)
 Frame = +1

Query: 508 GWRFLXSGDRLGHGXGYYDKFITNLRLNPETAPKIVAVAFNCQVVDEVPTTEQDXKV 678
           G  F   G R+G+G GYYD+F+  +    +  PK V++AF+  V+D VPT   D  V
Sbjct: 124 GLAFDSQGYRIGYGGGYYDRFLPKI---SDKVPK-VSLAFDEFVIDSVPTDSFDIPV 176


>UniRef50_A4SLF4 Cluster: 5-formyltetrahydrofolate cyclo-ligase
           family protein; n=10; Gammaproteobacteria|Rep:
           5-formyltetrahydrofolate cyclo-ligase family protein -
           Aeromonas salmonicida (strain A449)
          Length = 202

 Score = 41.9 bits (94), Expect = 0.023
 Identities = 21/60 (35%), Positives = 33/60 (55%)
 Frame = +1

Query: 517 FLXSGDRLGHGXGYYDKFITNLRLNPETAPKIVAVAFNCQVVDEVPTTEQDXKVXEVXFP 696
           F   G+RLG G GYYD+ +     + +  PK + +A +CQ VD VP  + D  + ++  P
Sbjct: 137 FDAEGNRLGMGGGYYDRTLACWHEH-KLGPKPLGLAHDCQQVDAVPQEQWDVPLPQIITP 195



 Score = 39.5 bits (88), Expect = 0.13
 Identities = 29/121 (23%), Positives = 58/121 (47%), Gaps = 1/121 (0%)
 Frame = +2

Query: 146 LRNEIAAKIAALTNEEKKRQSQIVYEKVINHSWYKSSSRIALYMSTENEIDTAPLIKHIQ 325
           LR  I  +  +L+  E++  +Q +  +   HS   ++ RIALY++ + E++  P I  + 
Sbjct: 15  LRQLIRLRRKSLSQAEQQEAAQQLVAQFKQHSEILAARRIALYLANDGELNPLPAIHWLW 74

Query: 326 ARGAAAFVP-QYAGGRMRMLHLETGDEQTMPKTKHGISQHGKDQARDDALETGGLDLIIA 502
           A+    ++P  +      +L L       M + ++GI++   D ++   +    LDLI  
Sbjct: 75  AQQKEVYLPVLHPFTPGHLLFLRYTATSPMTRNRYGIAEPELDMSQ--VVPHSTLDLICT 132

Query: 503 P 505
           P
Sbjct: 133 P 133


>UniRef50_A1URD6 Cluster: 5,10-methenyltetrahydrofolate synthetase;
           n=3; Bartonella|Rep: 5,10-methenyltetrahydrofolate
           synthetase - Bartonella bacilliformis (strain ATCC 35685
           / KC583)
          Length = 212

 Score = 41.9 bits (94), Expect = 0.023
 Identities = 18/46 (39%), Positives = 28/46 (60%)
 Frame = +1

Query: 532 DRLGHGXGYYDKFITNLRLNPETAPKIVAVAFNCQVVDEVPTTEQD 669
           +RLG+G GYYD+ I  L+        +  + F+CQ V+ +P+TE D
Sbjct: 153 NRLGYGKGYYDRAIAALKAEGHCI-DLFGLGFSCQEVESIPSTEHD 197


>UniRef50_Q5KX52 Cluster: 5-formyltetrahydrofolate cyclo-ligase;
           n=2; Geobacillus|Rep: 5-formyltetrahydrofolate
           cyclo-ligase - Geobacillus kaustophilus
          Length = 190

 Score = 41.5 bits (93), Expect = 0.031
 Identities = 19/54 (35%), Positives = 32/54 (59%)
 Frame = +1

Query: 517 FLXSGDRLGHGXGYYDKFITNLRLNPETAPKIVAVAFNCQVVDEVPTTEQDXKV 678
           F  +G R+G+G GYYD+++      P  +    A+A++ QV+D++P  E D  V
Sbjct: 129 FAKTGYRIGYGGGYYDRYL------PGASAVTAALAYSFQVMDDIPAEEHDVPV 176


>UniRef50_Q180V5 Cluster: Putative 5-formyltetrahydrofolate
           cyclo-ligase; n=2; Clostridium difficile|Rep: Putative
           5-formyltetrahydrofolate cyclo-ligase - Clostridium
           difficile (strain 630)
          Length = 189

 Score = 41.5 bits (93), Expect = 0.031
 Identities = 18/48 (37%), Positives = 30/48 (62%)
 Frame = +1

Query: 535 RLGHGXGYYDKFITNLRLNPETAPKIVAVAFNCQVVDEVPTTEQDXKV 678
           RLG+G G+YD+F+ NLR +  T    + +AF+ Q+ D +P    D ++
Sbjct: 132 RLGYGGGFYDRFLENLRKDAIT----IGIAFDFQIFDSIPKETHDAQL 175


>UniRef50_Q0YQW9 Cluster: 5-formyltetrahydrofolate cyclo-ligase;
           n=2; Chlorobium/Pelodictyon group|Rep:
           5-formyltetrahydrofolate cyclo-ligase - Chlorobium
           ferrooxidans DSM 13031
          Length = 207

 Score = 41.5 bits (93), Expect = 0.031
 Identities = 21/51 (41%), Positives = 30/51 (58%)
 Frame = +1

Query: 517 FLXSGDRLGHGXGYYDKFITNLRLNPETAPKIVAVAFNCQVVDEVPTTEQD 669
           F  SG RLG+G G+YD+F+  L L     P  + +AF+ Q++D VP    D
Sbjct: 142 FDRSGYRLGYGKGFYDRFLHRLSLE-GFRPLRIGLAFSMQMIDTVPHDSWD 191


>UniRef50_Q0ALV8 Cluster: 5-formyltetrahydrofolate cyclo-ligase;
           n=1; Maricaulis maris MCS10|Rep:
           5-formyltetrahydrofolate cyclo-ligase - Maricaulis maris
           (strain MCS10)
          Length = 199

 Score = 41.5 bits (93), Expect = 0.031
 Identities = 20/48 (41%), Positives = 28/48 (58%)
 Frame = +1

Query: 526 SGDRLGHGXGYYDKFITNLRLNPETAPKIVAVAFNCQVVDEVPTTEQD 669
           SG+RLG G GYYD  +  LR   +   + V +AF+CQV+  +P    D
Sbjct: 129 SGNRLGFGKGYYDYTLAALRAAGQV--RAVGLAFDCQVLATIPAERHD 174


>UniRef50_A4WE63 Cluster: 5-formyltetrahydrofolate cyclo-ligase;
           n=25; Gammaproteobacteria|Rep: 5-formyltetrahydrofolate
           cyclo-ligase - Enterobacter sp. 638
          Length = 198

 Score = 41.5 bits (93), Expect = 0.031
 Identities = 33/136 (24%), Positives = 65/136 (47%), Gaps = 4/136 (2%)
 Frame = +2

Query: 110 MSPIKPNPA-KALLRNEIAAKIAALTNEEKKRQSQIVYEKVINHSWYKSSSRIALYMSTE 286
           M+ +   PA +  +R  I  +   LT +++   +Q    +++ +S    +  +AL++S +
Sbjct: 1   MTQLSEVPASRQEIRQFIRKQRRTLTPDQQAHFAQQASARMMAYSPVVMAHTVALFLSFD 60

Query: 287 NEIDTAPLIKHIQARGAAAFVP---QYAGGRMRMLHLETGDEQTMPKTKHGISQHGKDQA 457
            E+DT PLI+ +   G   ++P    ++ G +  LH     E  + + K  I++   D  
Sbjct: 61  GELDTQPLIEQLWRAGKKVYLPVLHPFSPGNLLFLHYHPHSELVVNRLK--ITEPKLDVR 118

Query: 458 RDDALETGGLDLIIAP 505
             D L    LD++I P
Sbjct: 119 --DVLPLNELDVLITP 132



 Score = 34.3 bits (75), Expect = 4.7
 Identities = 19/56 (33%), Positives = 29/56 (51%)
 Frame = +1

Query: 529 GDRLGHGXGYYDKFITNLRLNPETAPKIVAVAFNCQVVDEVPTTEQDXKVXEVXFP 696
           G RLG G G+YD+ + N +   +   + V  A +CQ VD +P  + D  +  V  P
Sbjct: 140 GQRLGMGGGFYDRTLQNWQ---QHGLQPVGYAHDCQGVDMLPVEKWDIPLPAVVTP 192


>UniRef50_Q7P0R7 Cluster: Probable 5-formyltetrahydrofolate
           cyclo-ligase; n=1; Chromobacterium violaceum|Rep:
           Probable 5-formyltetrahydrofolate cyclo-ligase -
           Chromobacterium violaceum
          Length = 203

 Score = 41.1 bits (92), Expect = 0.041
 Identities = 20/51 (39%), Positives = 30/51 (58%), Gaps = 1/51 (1%)
 Frame = +1

Query: 529 GDRLGHGXGYYDKFITNLRLNPETA-PKIVAVAFNCQVVDEVPTTEQDXKV 678
           G R+G G G+YD  +   R +  +  P +V VAF+CQ+VD VP    D ++
Sbjct: 134 GYRMGQGGGFYDSTLAFRRRHALSGKPLLVGVAFDCQLVDAVPREAWDVRL 184


>UniRef50_Q57BF7 Cluster: 5-formyltetrahydrofolate cyclo-ligase
           family protein; n=15; Rhizobiales|Rep:
           5-formyltetrahydrofolate cyclo-ligase family protein -
           Brucella abortus
          Length = 198

 Score = 41.1 bits (92), Expect = 0.041
 Identities = 18/53 (33%), Positives = 29/53 (54%)
 Frame = +1

Query: 529 GDRLGHGXGYYDKFITNLRLNPETAPKIVAVAFNCQVVDEVPTTEQDXKVXEV 687
           G RLG+G G+YD+ +          P ++ +AF+CQ VD VP    D  + ++
Sbjct: 135 GHRLGYGAGHYDRALARF-AERGLQPLLIGMAFDCQEVDYVPNEPHDIALHQI 186


>UniRef50_Q0SQM2 Cluster: 5-formyltetrahydrofolate cyclo-ligase
           family protein; n=3; Clostridium perfringens|Rep:
           5-formyltetrahydrofolate cyclo-ligase family protein -
           Clostridium perfringens (strain SM101 / Type A)
          Length = 192

 Score = 41.1 bits (92), Expect = 0.041
 Identities = 23/57 (40%), Positives = 34/57 (59%)
 Frame = +1

Query: 508 GWRFLXSGDRLGHGXGYYDKFITNLRLNPETAPKIVAVAFNCQVVDEVPTTEQDXKV 678
           G  F   G+RLG+G G+YD+F++     P +  K VA+ ++ QV DE+P    D KV
Sbjct: 126 GLAFDLKGNRLGYGGGFYDRFLSKY---PNS--KRVALCYDFQVFDEIPHEFFDEKV 177



 Score = 35.9 bits (79), Expect = 1.5
 Identities = 18/73 (24%), Positives = 36/73 (49%)
 Frame = +2

Query: 137 KALLRNEIAAKIAALTNEEKKRQSQIVYEKVINHSWYKSSSRIALYMSTENEIDTAPLIK 316
           K  LR EI  K   +    K    + + + ++    YK+S  + +Y++ ++E++T  +IK
Sbjct: 3   KGELRKEIKLKRENIDRNTKLMADEKIRKTLLESEIYKNSKVVFIYVNMDSEVNTVEIIK 62

Query: 317 HIQARGAAAFVPQ 355
            + A      VP+
Sbjct: 63  ELLASDKKVAVPK 75


>UniRef50_A1WW94 Cluster: 5-formyltetrahydrofolate cyclo-ligase;
           n=1; Halorhodospira halophila SL1|Rep:
           5-formyltetrahydrofolate cyclo-ligase - Halorhodospira
           halophila (strain DSM 244 / SL1)
           (Ectothiorhodospirahalophila (strain DSM 244 / SL1))
          Length = 203

 Score = 41.1 bits (92), Expect = 0.041
 Identities = 20/46 (43%), Positives = 27/46 (58%)
 Frame = +1

Query: 517 FLXSGDRLGHGXGYYDKFITNLRLNPETAPKIVAVAFNCQVVDEVP 654
           F  +G RLG G G+YD     LR  P   P+IV +AF+ Q V ++P
Sbjct: 128 FDPAGRRLGMGGGFYDATFARLRRYPWHPPRIVGLAFSSQEVAQLP 173


>UniRef50_A2SSS2 Cluster: 5-formyltetrahydrofolate cyclo-ligase;
           n=1; Methanocorpusculum labreanum Z|Rep:
           5-formyltetrahydrofolate cyclo-ligase -
           Methanocorpusculum labreanum (strain ATCC 43576 / DSM
           4855 / Z)
          Length = 196

 Score = 41.1 bits (92), Expect = 0.041
 Identities = 23/57 (40%), Positives = 34/57 (59%)
 Frame = +1

Query: 517 FLXSGDRLGHGXGYYDKFITNLRLNPETAPKIVAVAFNCQVVDEVPTTEQDXKVXEV 687
           F  +G RLG+G GYYD+F      NP+  P+I  +A+ CQ V+ +PT   D ++  V
Sbjct: 125 FDRAGHRLGYGAGYYDRFFEK---NPD-IPRI-GMAYACQEVELIPTEPFDARMDYV 176


>UniRef50_Q8G439 Cluster: Putative uncharacterized protein; n=1;
           Bifidobacterium longum|Rep: Putative uncharacterized
           protein - Bifidobacterium longum
          Length = 249

 Score = 40.7 bits (91), Expect = 0.054
 Identities = 21/77 (27%), Positives = 40/77 (51%)
 Frame = +2

Query: 137 KALLRNEIAAKIAALTNEEKKRQSQIVYEKVINHSWYKSSSRIALYMSTENEIDTAPLIK 316
           KA LR+ I ++   +  EE+    +++  +   H   +    +A Y+S  +EI+T PL++
Sbjct: 28  KATLRHHILSRRKRVPAEERGAAGELLVRRFPAHM-IQDGPTVAAYVSMGSEIETRPLLR 86

Query: 317 HIQARGAAAFVPQYAGG 367
            ++A G    VP+   G
Sbjct: 87  WLRAHGCHVLVPRLGSG 103


>UniRef50_Q7MTT7 Cluster: 5-formyltetrahydrofolate cyclo-ligase
           family protein; n=1; Porphyromonas gingivalis|Rep:
           5-formyltetrahydrofolate cyclo-ligase family protein -
           Porphyromonas gingivalis (Bacteroides gingivalis)
          Length = 185

 Score = 40.7 bits (91), Expect = 0.054
 Identities = 19/54 (35%), Positives = 31/54 (57%)
 Frame = +1

Query: 508 GWRFLXSGDRLGHGXGYYDKFITNLRLNPETAPKIVAVAFNCQVVDEVPTTEQD 669
           G  F   G R+G G GYYD+F+      P T  +++ V F+ ++++E+PT   D
Sbjct: 123 GVAFDRKGSRMGRGKGYYDRFL------PATQVRLIGVTFSYRLLEELPTDPWD 170


>UniRef50_Q5WH98 Cluster: 5-formyltetrahydrofolate cyclo-ligase;
           n=1; Bacillus clausii KSM-K16|Rep:
           5-formyltetrahydrofolate cyclo-ligase - Bacillus clausii
           (strain KSM-K16)
          Length = 187

 Score = 40.7 bits (91), Expect = 0.054
 Identities = 27/125 (21%), Positives = 60/125 (48%)
 Frame = +2

Query: 134 AKALLRNEIAAKIAALTNEEKKRQSQIVYEKVINHSWYKSSSRIALYMSTENEIDTAPLI 313
           +K  +RN+++ ++  L     K++S  + + ++    +  ++ IAL +S   E++TAPLI
Sbjct: 3   SKQNIRNDVSKQLNMLPAHVYKQRSTRLADLLMQQDVWNQATTIALTVSRFPEVETAPLI 62

Query: 314 KHIQARGAAAFVPQYAGGRMRMLHLETGDEQTMPKTKHGISQHGKDQARDDALETGGLDL 493
               A      +P+       M        + + + K+G+ +  +++A    +    L+L
Sbjct: 63  AGALAENKKVVLPRINMKERTMAFFYITSTEELVENKYGLFEPKQEEA--CLVRPDELEL 120

Query: 494 IIAPG 508
           I+ PG
Sbjct: 121 IVVPG 125



 Score = 36.7 bits (81), Expect = 0.88
 Identities = 20/60 (33%), Positives = 31/60 (51%)
 Frame = +1

Query: 508 GWRFLXSGDRLGHGXGYYDKFITNLRLNPETAPKIVAVAFNCQVVDEVPTTEQDXKVXEV 687
           G  F  +G RLG G G+YD+F+      P  +   VA+ F  Q+  ++PT   D  + +V
Sbjct: 125 GVAFTKAGKRLGLGGGFYDRFL------PSCSGLTVALCFREQLFSDLPTEPHDVLIDKV 178


>UniRef50_A0W837 Cluster: 5-formyltetrahydrofolate cyclo-ligase;
           n=2; Desulfuromonadales|Rep: 5-formyltetrahydrofolate
           cyclo-ligase - Geobacter lovleyi SZ
          Length = 197

 Score = 40.7 bits (91), Expect = 0.054
 Identities = 34/124 (27%), Positives = 57/124 (45%)
 Frame = +2

Query: 137 KALLRNEIAAKIAALTNEEKKRQSQIVYEKVINHSWYKSSSRIALYMSTENEIDTAPLIK 316
           K  LR+++ A   A+ +   +  S     ++I+   ++ ++ IALY   + EIDT  L  
Sbjct: 3   KKSLRSDLLAHRRAIDHALWQDASTAAQLRLISLEAFQRAACIALYSPIQREIDTGLLFS 62

Query: 317 HIQARGAAAFVPQYAGGRMRMLHLETGDEQTMPKTKHGISQHGKDQARDDALETGGLDLI 496
             +++G     P   G  ++   +    EQ  P    GI +  +    D ALET   DLI
Sbjct: 63  KARSKGKRVLYPLVCGATLQFREV-NAPEQCTPGA-FGILEPCR-LGEDHALETA--DLI 117

Query: 497 IAPG 508
           + PG
Sbjct: 118 VVPG 121


>UniRef50_P0AC29 Cluster: Uncharacterized protein ygfA; n=23;
           Enterobacteriaceae|Rep: Uncharacterized protein ygfA -
           Escherichia coli O157:H7
          Length = 182

 Score = 40.7 bits (91), Expect = 0.054
 Identities = 28/113 (24%), Positives = 54/113 (47%), Gaps = 3/113 (2%)
 Frame = +2

Query: 176 ALTNEEKKRQSQIVYEKVINHSWYKSSSRIALYMSTENEIDTAPLIKHIQARGAAAFVP- 352
           ALT E+++   Q    +++ +     +  +A+++S + E+DT PLI+ +   G   ++P 
Sbjct: 8   ALTPEQQQEMGQQAATRMMTYPPVVMAHTVAVFLSFDGELDTQPLIEQLWRAGKRVYLPV 67

Query: 353 --QYAGGRMRMLHLETGDEQTMPKTKHGISQHGKDQARDDALETGGLDLIIAP 505
              ++ G +  L+     E  M + K  I +   D    D L    LD++I P
Sbjct: 68  LHPFSAGNLLFLNYHPQSELVMNRLK--IHEPKLDVR--DVLPLSRLDVLITP 116



 Score = 39.5 bits (88), Expect = 0.13
 Identities = 21/56 (37%), Positives = 33/56 (58%)
 Frame = +1

Query: 529 GDRLGHGXGYYDKFITNLRLNPETAPKIVAVAFNCQVVDEVPTTEQDXKVXEVXFP 696
           G RLG G G+YD+ + N + + +T P  V  A +CQ+V+++P  E D  +  V  P
Sbjct: 124 GQRLGMGGGFYDRTLQNWQ-HYKTQP--VGYAHDCQLVEKLPVEEWDIPLPAVVTP 176


>UniRef50_A0RTU2 Cluster: 5-formyltetrahydrofolate cyclo-ligase;
           n=1; Cenarchaeum symbiosum|Rep: 5-formyltetrahydrofolate
           cyclo-ligase - Cenarchaeum symbiosum
          Length = 173

 Score = 40.3 bits (90), Expect = 0.072
 Identities = 22/50 (44%), Positives = 29/50 (58%)
 Frame = +1

Query: 529 GDRLGHGXGYYDKFITNLRLNPETAPKIVAVAFNCQVVDEVPTTEQDXKV 678
           G RLG+G GYYD+F+  L +     P IV   ++ Q+V  VPT E D  V
Sbjct: 118 GSRLGYGRGYYDRFLAGLDI-----PSIVP-CYSKQLVKSVPTEEHDIPV 161


>UniRef50_Q72F49 Cluster: 5-formyltetrahydrofolate cyclo-ligase
           family protein; n=2; Desulfovibrio vulgaris subsp.
           vulgaris|Rep: 5-formyltetrahydrofolate cyclo-ligase
           family protein - Desulfovibrio vulgaris (strain
           Hildenborough / ATCC 29579 / NCIMB8303)
          Length = 283

 Score = 39.9 bits (89), Expect = 0.095
 Identities = 19/74 (25%), Positives = 37/74 (50%)
 Frame = +2

Query: 134 AKALLRNEIAAKIAALTNEEKKRQSQIVYEKVINHSWYKSSSRIALYMSTENEIDTAPLI 313
           AK  LR E+  +   L  EE +R   +    ++ H  + ++ ++ LY++  NE+DT  L+
Sbjct: 91  AKTALRREMLQRRRDLDREEAQRHGALAQAALLAHPAWVTARQVVLYVAVRNELDTDLLL 150

Query: 314 KHIQARGAAAFVPQ 355
           +     G    +P+
Sbjct: 151 RTAWEAGKEVLLPR 164



 Score = 39.1 bits (87), Expect = 0.17
 Identities = 21/57 (36%), Positives = 31/57 (54%)
 Frame = +1

Query: 508 GWRFLXSGDRLGHGXGYYDKFITNLRLNPETAPKIVAVAFNCQVVDEVPTTEQDXKV 678
           G  F   G+RLG+G GYYD+F++   +   +A  +V  A   Q+VD +P    D  V
Sbjct: 218 GVAFDRQGNRLGYGGGYYDRFLSTPGM---SATPLVGFAHAFQIVDALPAEAWDRPV 271


>UniRef50_Q31FB9 Cluster: 5-formyltetrahydrofolate cyclo-ligase;
           n=1; Thiomicrospira crunogena XCL-2|Rep:
           5-formyltetrahydrofolate cyclo-ligase - Thiomicrospira
           crunogena (strain XCL-2)
          Length = 192

 Score = 39.9 bits (89), Expect = 0.095
 Identities = 32/122 (26%), Positives = 54/122 (44%), Gaps = 2/122 (1%)
 Frame = +2

Query: 146 LRNEIAAKIAALTNEEKKRQSQIVYEKVINHSWYKSSSRIALYMSTENEIDTAPLIKHIQ 325
           LRN    K   L+ E++   ++     ++  +W +   RIA+Y S + E+ T  LI  + 
Sbjct: 3   LRNTCREKRNQLSPEQQFHHAKKASRLLLRSNWLQRPKRIAVYFSQDGELSTESLIDALW 62

Query: 326 ARGAAAFVPQYAGGRMR-MLHLETGDEQTMPKTKHGISQHGKDQARDDALETG-GLDLII 499
            R    F+P     R R M   E   +  +   + GI +    Q ++    TG  LDL++
Sbjct: 63  QRNHQVFLPVLKTLRGRHMAFAEYTPQSVLASNRFGILE---PQVQNQHHLTGQQLDLVL 119

Query: 500 AP 505
            P
Sbjct: 120 MP 121


>UniRef50_Q2RGK7 Cluster: 5-formyltetrahydrofolate cyclo-ligase
           precursor; n=1; Moorella thermoacetica ATCC 39073|Rep:
           5-formyltetrahydrofolate cyclo-ligase precursor -
           Moorella thermoacetica (strain ATCC 39073)
          Length = 202

 Score = 39.9 bits (89), Expect = 0.095
 Identities = 24/60 (40%), Positives = 33/60 (55%)
 Frame = +1

Query: 508 GWRFLXSGDRLGHGXGYYDKFITNLRLNPETAPKIVAVAFNCQVVDEVPTTEQDXKVXEV 687
           G  F  +G+RLG+G GYYD+F+  LR    T    +A+AF  Q+V +V     D  V  V
Sbjct: 124 GVAFDRAGNRLGYGGGYYDRFLATLRPGALT----IALAFAEQIVADVYPEVHDRPVDMV 179


>UniRef50_O67621 Cluster: Putative uncharacterized protein; n=1;
           Aquifex aeolicus|Rep: Putative uncharacterized protein -
           Aquifex aeolicus
          Length = 186

 Score = 39.9 bits (89), Expect = 0.095
 Identities = 21/86 (24%), Positives = 43/86 (50%)
 Frame = +2

Query: 137 KALLRNEIAAKIAALTNEEKKRQSQIVYEKVINHSWYKSSSRIALYMSTENEIDTAPLIK 316
           K+ LR ++  K   L+ EE++R S+ V   + +   +K S ++ALY   + E+D  PL  
Sbjct: 3   KSELRKKVLHKRINLSEEERRRLSEKVISNLKSLPEFKKSKKVALYCPIKGEVDLTPLFP 62

Query: 317 HIQARGAAAFVPQYAGGRMRMLHLET 394
            +  +     +P+  G  + +  + +
Sbjct: 63  EV-LKEKELILPKVEGNEISLYRVHS 87


>UniRef50_Q40JH2 Cluster: 5-formyltetrahydrofolate cyclo-ligase;
           n=5; canis group|Rep: 5-formyltetrahydrofolate
           cyclo-ligase - Ehrlichia chaffeensis str. Sapulpa
          Length = 180

 Score = 39.9 bits (89), Expect = 0.095
 Identities = 20/46 (43%), Positives = 28/46 (60%)
 Frame = +1

Query: 532 DRLGHGXGYYDKFITNLRLNPETAPKIVAVAFNCQVVDEVPTTEQD 669
           +RLG G GYYD  I+ L+ N     K++ VA++ Q+ D VPT   D
Sbjct: 123 NRLGFGGGYYDNTISKLKPN----CKVIGVAYDIQLCDIVPTESHD 164


>UniRef50_Q3VT50 Cluster: 5-formyltetrahydrofolate cyclo-ligase;
           n=1; Prosthecochloris aestuarii DSM 271|Rep:
           5-formyltetrahydrofolate cyclo-ligase - Prosthecochloris
           aestuarii DSM 271
          Length = 197

 Score = 39.9 bits (89), Expect = 0.095
 Identities = 20/51 (39%), Positives = 29/51 (56%)
 Frame = +1

Query: 526 SGDRLGHGXGYYDKFITNLRLNPETAPKIVAVAFNCQVVDEVPTTEQDXKV 678
           SG R+G+G G YD+F   L+    T P  V + F+ QV+D +P    D K+
Sbjct: 135 SGTRIGYGAGCYDRFFAALQKRGFT-PHAVGICFSFQVLDTLPFDPWDRKL 184


>UniRef50_Q1YVJ4 Cluster: 5-formyltetrahydrofolate cyclo-ligase
           family protein; n=1; gamma proteobacterium HTCC2207|Rep:
           5-formyltetrahydrofolate cyclo-ligase family protein -
           gamma proteobacterium HTCC2207
          Length = 195

 Score = 39.9 bits (89), Expect = 0.095
 Identities = 31/124 (25%), Positives = 59/124 (47%), Gaps = 4/124 (3%)
 Frame = +2

Query: 146 LRNEIAAKIAALTNEEKKRQSQIVYEKVINHSWYKSSSRIALYMSTENEIDTAPLIKHIQ 325
           +R+ I  K  AL   +++  S+ + + +    +++ + RI +Y++ + EID + ++    
Sbjct: 6   IRSNIREKRRALNPSQQRTASEQLAKLLCRQDFFQRAKRIGIYLANDGEIDPSAIVTAAF 65

Query: 326 ARGAAAFVPQYAGGRMRMLHL---ETGDEQTMPKTKHGISQHGKDQARDDAL-ETGGLDL 493
               A F+P     +   LH    + GD  T+ K + GI +    Q R  A+     LDL
Sbjct: 66  RAKKACFLPLIDPLKANSLHFAEYQLGD--TLHKNRFGILE---PQFRSTAITPPWSLDL 120

Query: 494 IIAP 505
           I+ P
Sbjct: 121 ILLP 124


>UniRef50_Q1V201 Cluster: 5-formyltetrahydrofolate cyclo-ligase;
           n=2; Candidatus Pelagibacter ubique|Rep:
           5-formyltetrahydrofolate cyclo-ligase - Candidatus
           Pelagibacter ubique HTCC1002
          Length = 182

 Score = 39.9 bits (89), Expect = 0.095
 Identities = 19/49 (38%), Positives = 28/49 (57%)
 Frame = +1

Query: 532 DRLGHGXGYYDKFITNLRLNPETAPKIVAVAFNCQVVDEVPTTEQDXKV 678
           +RLG+G GYYD+ I  L          + +AF+ Q +D+VPT   D K+
Sbjct: 125 NRLGYGGGYYDRLIEKLSKKKNIIK--IGLAFSIQEIDKVPTNMYDKKL 171


>UniRef50_A7IJU7 Cluster: 5-formyltetrahydrofolate cyclo-ligase;
           n=1; Xanthobacter autotrophicus Py2|Rep:
           5-formyltetrahydrofolate cyclo-ligase - Xanthobacter sp.
           (strain Py2)
          Length = 195

 Score = 39.9 bits (89), Expect = 0.095
 Identities = 19/50 (38%), Positives = 28/50 (56%)
 Frame = +1

Query: 529 GDRLGHGXGYYDKFITNLRLNPETAPKIVAVAFNCQVVDEVPTTEQDXKV 678
           G R+G+G G+YD+ +  LR   +   + +  AF CQ VD+VP    D  V
Sbjct: 132 GFRIGYGAGFYDRTLALLR--AQRPVRAIGFAFACQEVDQVPVETHDEPV 179


>UniRef50_A5VKU2 Cluster: 5-formyltetrahydrofolate cyclo-ligase;
           n=2; Lactobacillus reuteri|Rep: 5-formyltetrahydrofolate
           cyclo-ligase - Lactobacillus reuteri F275
          Length = 184

 Score = 39.9 bits (89), Expect = 0.095
 Identities = 31/127 (24%), Positives = 60/127 (47%), Gaps = 2/127 (1%)
 Frame = +2

Query: 134 AKALLRNEIAAKIAALTNEEKKRQSQIVYEKVINHSWYKSSSRIALYMSTENEIDTAPLI 313
           +K  LR    A++  L    +  + + +   + +   +  +  IA+ +S   EIDTAP+I
Sbjct: 4   SKKELRQAYIARLQQLDLNTRLYEERKLASLLYDQPEWTGAKTIAVTLSQSFEIDTAPII 63

Query: 314 KHIQARGAAAFVPQYAGGRMRMLHLETGDEQTMPKTKHGISQ--HGKDQARDDALETGGL 487
            H + +G    +P+    R +M  +E  ++    +T  GI +   GK  + D+      +
Sbjct: 64  LHARHKGQQIVIPRTLPHR-QMEFVELNEDTDFDETSFGILEPHDGKVYSPDE------I 116

Query: 488 DLIIAPG 508
           DL++ PG
Sbjct: 117 DLMVVPG 123



 Score = 35.9 bits (79), Expect = 1.5
 Identities = 19/47 (40%), Positives = 28/47 (59%)
 Frame = +1

Query: 508 GWRFLXSGDRLGHGXGYYDKFITNLRLNPETAPKIVAVAFNCQVVDE 648
           G  F  SG+RLG G GYYD+++ N +      PK V++A   Q+ +E
Sbjct: 123 GVAFTASGNRLGFGGGYYDRYLKNYK-----GPK-VSMALTTQLAEE 163


>UniRef50_Q83FP9 Cluster: Putative uncharacterized protein; n=2;
           Tropheryma whipplei|Rep: Putative uncharacterized
           protein - Tropheryma whipplei (strain Twist) (Whipple's
           bacillus)
          Length = 203

 Score = 39.5 bits (88), Expect = 0.13
 Identities = 19/53 (35%), Positives = 32/53 (60%)
 Frame = +1

Query: 529 GDRLGHGXGYYDKFITNLRLNPETAPKIVAVAFNCQVVDEVPTTEQDXKVXEV 687
           G RLG G GYYD+++  ++    + P + AV F+ ++ DE+P  + D K+  V
Sbjct: 133 GYRLGWGKGYYDRYLARVK---RSIP-VFAVVFDNEIFDEIPINDWDKKLTGV 181


>UniRef50_Q74E28 Cluster: 5-formyltetrahydrofolate cyclo-ligase
           family protein; n=2; Geobacter|Rep:
           5-formyltetrahydrofolate cyclo-ligase family protein -
           Geobacter sulfurreducens
          Length = 187

 Score = 39.5 bits (88), Expect = 0.13
 Identities = 31/127 (24%), Positives = 55/127 (43%), Gaps = 3/127 (2%)
 Frame = +2

Query: 137 KALLRNEIAAKIAALTNEEKKRQSQIVYEKVINHSWYKSSSRIALYMSTENEIDTAPLIK 316
           K +LR  + A   +L   E +  S+ +    +    ++++  IALY     E+DT+ +++
Sbjct: 3   KRVLRQSMLALRKSLAPVEARWASEAIQRSFVESEGFRNARVIALYAPIRGEVDTSDVLR 62

Query: 317 HIQARGAAAFVPQYAGGRMRMLHLETGDEQTMPKTKHGISQ---HGKDQARDDALETGGL 487
               +G    +P   G  +R   +E  D   +     GI +    GK  A D A      
Sbjct: 63  LALDQGKTVLLPAVCGDELRF--IEVTDPAGLRSGSFGIPEPCLTGKAVAPDCA------ 114

Query: 488 DLIIAPG 508
           D+I+ PG
Sbjct: 115 DIIVVPG 121



 Score = 33.5 bits (73), Expect = 8.2
 Identities = 16/48 (33%), Positives = 29/48 (60%)
 Frame = +1

Query: 508 GWRFLXSGDRLGHGXGYYDKFITNLRLNPETAPKIVAVAFNCQVVDEV 651
           G  F  +G R+G+G G+YD+ + +L    E   ++V   ++ Q+VDE+
Sbjct: 121 GVAFDLAGHRIGYGKGFYDRALHHL----EGTGRLVGFCYDFQLVDEI 164


>UniRef50_O83692 Cluster: 5,10-methenyltetrahydrofolate synthetase,
           putative; n=1; Treponema pallidum|Rep:
           5,10-methenyltetrahydrofolate synthetase, putative -
           Treponema pallidum
          Length = 225

 Score = 39.5 bits (88), Expect = 0.13
 Identities = 18/58 (31%), Positives = 30/58 (51%), Gaps = 1/58 (1%)
 Frame = +1

Query: 517 FLXSGDRLGHGXGYYDKFITNLRLN-PETAPKIVAVAFNCQVVDEVPTTEQDXKVXEV 687
           F  +G RLG G G+YD+F+  +    P  +   + + F+CQ++  +P    D  V  V
Sbjct: 147 FSTNGARLGRGGGHYDRFLARIAATIPAGSYYTLGLCFDCQIMAVIPQEAHDQSVHAV 204


>UniRef50_Q0HZ35 Cluster: 5-formyltetrahydrofolate cyclo-ligase;
           n=10; Gammaproteobacteria|Rep: 5-formyltetrahydrofolate
           cyclo-ligase - Shewanella sp. (strain MR-7)
          Length = 228

 Score = 39.5 bits (88), Expect = 0.13
 Identities = 31/136 (22%), Positives = 65/136 (47%), Gaps = 4/136 (2%)
 Frame = +2

Query: 110 MSP-IKPNPAKALLRNEIAAKIAALTNEEKKRQSQIVYEKVINHSWYKSSSRIALYMSTE 286
           +SP + P  ++A LR +I     +L  E +   S     +++      ++  +ALY++ +
Sbjct: 30  LSPNLSPTLSRAELRKQIRLARRSLPIEVQTEASLAAGLRMLEKLSALNAQHVALYLTHD 89

Query: 287 NEIDTAPLIKHIQARGAAAFVPQ---YAGGRMRMLHLETGDEQTMPKTKHGISQHGKDQA 457
            E+ TAPLI+ +  +G   ++P+   +  G++  LH     +  M   + GI +   D  
Sbjct: 90  GELATAPLIEALWQQGIQTYLPRLHPFNAGQLLFLHYHA--DSPMQPNQFGILEPKLDVR 147

Query: 458 RDDALETGGLDLIIAP 505
               +E   +D+++ P
Sbjct: 148 AVMPIE--HIDVVVTP 161



 Score = 35.5 bits (78), Expect = 2.0
 Identities = 18/60 (30%), Positives = 28/60 (46%)
 Frame = +1

Query: 517 FLXSGDRLGHGXGYYDKFITNLRLNPETAPKIVAVAFNCQVVDEVPTTEQDXKVXEVXFP 696
           F   G+R+G G GYYD+ + N     +  P  +  A +CQ V  +P    D  +  +  P
Sbjct: 165 FDIKGNRMGMGGGYYDRTLANWHAKGKPLP--MGYAHDCQQVTTLPCEHWDVPLPAIITP 222


>UniRef50_A4E9T0 Cluster: Putative uncharacterized protein; n=1;
           Collinsella aerofaciens ATCC 25986|Rep: Putative
           uncharacterized protein - Collinsella aerofaciens ATCC
           25986
          Length = 198

 Score = 39.5 bits (88), Expect = 0.13
 Identities = 22/57 (38%), Positives = 34/57 (59%)
 Frame = +1

Query: 517 FLXSGDRLGHGXGYYDKFITNLRLNPETAPKIVAVAFNCQVVDEVPTTEQDXKVXEV 687
           F  +G RLG+G G YD+++    L+P  A +I+ +AF+ Q VD VPT   D  +  +
Sbjct: 143 FDQTGARLGYGGGCYDRYLP--MLSP--ACQIIGIAFDEQRVDRVPTDAHDLPLPHI 195


>UniRef50_P44905 Cluster: Uncharacterized protein HI0858; n=16;
           Gammaproteobacteria|Rep: Uncharacterized protein HI0858
           - Haemophilus influenzae
          Length = 187

 Score = 39.5 bits (88), Expect = 0.13
 Identities = 20/57 (35%), Positives = 32/57 (56%)
 Frame = +1

Query: 517 FLXSGDRLGHGXGYYDKFITNLRLNPETAPKIVAVAFNCQVVDEVPTTEQDXKVXEV 687
           F   G+RLG G G+YD+ + N + N    P  V +A+ CQ V+ +PT   D  + ++
Sbjct: 131 FDKKGNRLGMGGGFYDRTLQNWQ-NKSFIP--VGLAYQCQQVENLPTEHWDVPLFDI 184


>UniRef50_Q5HNZ9 Cluster: 5-formyltetrahydrofolate cyclo-ligase
           family protein; n=4; Staphylococcus|Rep:
           5-formyltetrahydrofolate cyclo-ligase family protein -
           Staphylococcus epidermidis (strain ATCC 35984 / RP62A)
          Length = 183

 Score = 39.1 bits (87), Expect = 0.17
 Identities = 28/121 (23%), Positives = 51/121 (42%)
 Frame = +2

Query: 146 LRNEIAAKIAALTNEEKKRQSQIVYEKVINHSWYKSSSRIALYMSTENEIDTAPLIKHIQ 325
           LR  I  K+ +   E+K    + + +K+     Y+ ++ I   +S  +E++T P+I H  
Sbjct: 6   LRRNIIKKMKSYDKEQKYLADEWLAKKLYQSEAYRKANTIGFVLSMPHEVNTYPIITHSL 65

Query: 326 ARGAAAFVPQYAGGRMRMLHLETGDEQTMPKTKHGISQHGKDQARDDALETGGLDLIIAP 505
                 FVP+    +  M   +    + + K   GI  H           T  +DL++ P
Sbjct: 66  NNNKKIFVPETNYQQQDMTFKQLLSIEDIEKDSKGI-YHSISPVG----TTNKMDLVVVP 120

Query: 506 G 508
           G
Sbjct: 121 G 121


>UniRef50_Q5FIZ8 Cluster: 5-formyltetrahydrofolate cyclo-ligase;
           n=1; Lactobacillus acidophilus|Rep:
           5-formyltetrahydrofolate cyclo-ligase - Lactobacillus
           acidophilus
          Length = 187

 Score = 39.1 bits (87), Expect = 0.17
 Identities = 30/110 (27%), Positives = 51/110 (46%), Gaps = 1/110 (0%)
 Frame = +2

Query: 182 TNEEKKRQSQIVYEKVINHSWYKSSSRIALYMSTENEIDTAPLIKHIQARGAAAFVPQYA 361
           T EEKK +  ++ EK++  +  K+S  I +  S   E+DT+ LI  +   G   ++ +  
Sbjct: 19  TTEEKKIEDAVLLEKLMGTNLIKNSQTIGVTASMPFEVDTSELIARLWDLGKEVYLAKAR 78

Query: 362 GGRMRML-HLETGDEQTMPKTKHGISQHGKDQARDDALETGGLDLIIAPG 508
             +   L  L       + K+K G+    ++ A   A     LDL+I PG
Sbjct: 79  TDQNHTLDFLHYTYMSKLVKSKFGV----EEIADKSAKVNNELDLVIVPG 124


>UniRef50_Q1MZK4 Cluster: 5-formyltetrahydrofolate cyclo-ligase
           family protein; n=1; Oceanobacter sp. RED65|Rep:
           5-formyltetrahydrofolate cyclo-ligase family protein -
           Oceanobacter sp. RED65
          Length = 239

 Score = 39.1 bits (87), Expect = 0.17
 Identities = 19/51 (37%), Positives = 28/51 (54%)
 Frame = +1

Query: 517 FLXSGDRLGHGXGYYDKFITNLRLNPETAPKIVAVAFNCQVVDEVPTTEQD 669
           F   G RLG G G+YD+    LR +    PK++ +A + Q V+ +P  E D
Sbjct: 174 FDQQGGRLGMGGGFYDRSFEFLRHSTLPKPKLIGLAHSFQQVESLPIEEWD 224


>UniRef50_Q0RC09 Cluster: Putative ligase; n=1; Frankia alni
           ACN14a|Rep: Putative ligase - Frankia alni (strain
           ACN14a)
          Length = 262

 Score = 39.1 bits (87), Expect = 0.17
 Identities = 22/65 (33%), Positives = 35/65 (53%)
 Frame = +1

Query: 526 SGDRLGHGXGYYDKFITNLRLNPETAPKIVAVAFNCQVVDEVPTTEQDXKVXEVXFPXXX 705
           +G RLG G G YD+ +   R+ P+    ++AV ++ +++D VPT E D  V  +  P   
Sbjct: 189 AGRRLGRGGGSYDRALR--RVAPDV--PVIAVLYDQELLDLVPTEEHDRSVKIIVTPSRT 244

Query: 706 LXLXP 720
           L   P
Sbjct: 245 LRCEP 249


>UniRef50_Q049I2 Cluster: 5-formyltetrahydrofolate cyclo-ligase;
           n=1; Lactobacillus delbrueckii subsp. bulgaricus ATCC
           BAA-365|Rep: 5-formyltetrahydrofolate cyclo-ligase -
           Lactobacillus delbrueckii subsp. bulgaricus (strain ATCC
           BAA-365)
          Length = 190

 Score = 39.1 bits (87), Expect = 0.17
 Identities = 27/106 (25%), Positives = 52/106 (49%), Gaps = 1/106 (0%)
 Frame = +2

Query: 194 KKRQSQIVYEKVINHSWYKSSSRIALYMSTENEIDTAPLIKHIQARGAAAFVPQ-YAGGR 370
           KKRQ Q +    + H   + + +I L +    E+D   LIK ++  G   ++ + + G +
Sbjct: 27  KKRQDQELTSLALQHPLVQEAKKIGLTLPMLLEVDINGLIKELRGEGKELYLAKCHPGWQ 86

Query: 371 MRMLHLETGDEQTMPKTKHGISQHGKDQARDDALETGGLDLIIAPG 508
           +  L  + G    + +TK G+ +  +++  D+A     LDL+  PG
Sbjct: 87  LDFLKWDEG--APLMQTKFGVWELAEEKEADNA-----LDLLFVPG 125


>UniRef50_A0JYX4 Cluster: 5-formyltetrahydrofolate cyclo-ligase;
           n=2; Arthrobacter|Rep: 5-formyltetrahydrofolate
           cyclo-ligase - Arthrobacter sp. (strain FB24)
          Length = 198

 Score = 39.1 bits (87), Expect = 0.17
 Identities = 22/65 (33%), Positives = 31/65 (47%), Gaps = 2/65 (3%)
 Frame = +1

Query: 526 SGDRLGHGXGYYDKFITNLRLNPETAPKIVAVAFNCQVV--DEVPTTEQDXKVXEVXFPX 699
           SG+R+G G GYYDKF+  L       P   AV F+ +++    +P    D KV     P 
Sbjct: 134 SGNRIGQGGGYYDKFLAGLEAAGRPVP-AAAVVFDGEILPAGTIPAESFDRKVPVAVTPS 192

Query: 700 XXLXL 714
             + L
Sbjct: 193 RLMQL 197


>UniRef50_Q9FYA5 Cluster: 5-formyltetrahydrofolate cyclo-ligase-like
           protein; n=10; Magnoliophyta|Rep:
           5-formyltetrahydrofolate cyclo-ligase-like protein -
           Arabidopsis thaliana (Mouse-ear cress)
          Length = 287

 Score = 39.1 bits (87), Expect = 0.17
 Identities = 32/138 (23%), Positives = 62/138 (44%), Gaps = 14/138 (10%)
 Frame = +2

Query: 137 KALLRNEIAAKIAALTNEEKKRQSQIVYEKVINHSWYKSSSRIALYMSTE--NEIDTAPL 310
           K ++R+ +   + A+    + +Q + + + V+   W+KS   +  Y+S +  NE+DT+ +
Sbjct: 18  KRVVRSTVRKSLKAMDPSLRTQQDEAIQKTVLEAPWFKSCKGLCAYISCKSLNEVDTSKI 77

Query: 311 IKHIQARGAA-----AFVP--QYAGGRMRMLHLETGDEQTMPKTK----HGISQHGKDQA 457
           +  I     +      +VP  +     MRMLH+   ++             +   G D  
Sbjct: 78  LSEILQHPDSNTQKKLYVPWVEDKNSNMRMLHISHMEDLVANSMNILEPAPVDAQGND-- 135

Query: 458 RDDALETG-GLDLIIAPG 508
           R+D L+    +DL I PG
Sbjct: 136 REDVLQADEPIDLFILPG 153



 Score = 36.7 bits (81), Expect = 0.88
 Identities = 21/77 (27%), Positives = 38/77 (49%), Gaps = 6/77 (7%)
 Frame = +1

Query: 508 GWRFLXSGDRLGHGXGYYDKFITNLRLNPETA----PKIVAVAFNCQVVDE--VPTTEQD 669
           G  F   G RLG G GYYD F+   +   +      P +VA++++ Q++++  +P T  D
Sbjct: 153 GLAFDRCGRRLGRGGGYYDTFLKRYQDRAKEKGWRYPLMVALSYSPQILEDGSIPVTPND 212

Query: 670 XKVXEVXFPXXXLXLXP 720
             +  +  P   + + P
Sbjct: 213 VLIDALVTPSGVVPITP 229


>UniRef50_Q011H2 Cluster: Predicted methyltransferase; n=2;
           Ostreococcus|Rep: Predicted methyltransferase -
           Ostreococcus tauri
          Length = 515

 Score = 39.1 bits (87), Expect = 0.17
 Identities = 20/49 (40%), Positives = 29/49 (59%), Gaps = 5/49 (10%)
 Frame = +1

Query: 508 GWRFLXSGDRLGHGXGYYDKFITN-----LRLNPETAPKIVAVAFNCQV 639
           G+ F   G RLG G GYYD F+       +R+N  + P +VA+A+ CQ+
Sbjct: 123 GFAFGEDGRRLGRGGGYYDAFLARYADACVRVN-ASPPLVVALAYECQI 170


>UniRef50_UPI0000384628 Cluster: COG0212: 5-formyltetrahydrofolate
           cyclo-ligase; n=1; Magnetospirillum magnetotacticum
           MS-1|Rep: COG0212: 5-formyltetrahydrofolate cyclo-ligase
           - Magnetospirillum magnetotacticum MS-1
          Length = 193

 Score = 38.7 bits (86), Expect = 0.22
 Identities = 20/47 (42%), Positives = 28/47 (59%)
 Frame = +1

Query: 529 GDRLGHGXGYYDKFITNLRLNPETAPKIVAVAFNCQVVDEVPTTEQD 669
           G RLG+G GYYD+ +++LR     A   + +AF  Q V+ VPT   D
Sbjct: 131 GFRLGYGGGYYDRTLSDLR--RRGAVPAIGLAFAAQEVERVPTDPWD 175


>UniRef50_Q0TWV8 Cluster: Predicted protein; n=1; Phaeosphaeria
           nodorum|Rep: Predicted protein - Phaeosphaeria nodorum
           (Septoria nodorum)
          Length = 742

 Score = 38.7 bits (86), Expect = 0.22
 Identities = 18/54 (33%), Positives = 30/54 (55%)
 Frame = +2

Query: 317 HIQARGAAAFVPQYAGGRMRMLHLETGDEQTMPKTKHGISQHGKDQARDDALET 478
           H Q  G  A  P++ GG++   HL  G ++ MP  +   SQ G+ QAR+  +++
Sbjct: 4   HQQGHGGGAHQPEFHGGQVPQQHLNAGQQRQMPTMQQKASQ-GQQQARNPYVDS 56


>UniRef50_Q2FMV3 Cluster: 5-formyltetrahydrofolate cyclo-ligase;
           n=1; Methanospirillum hungatei JF-1|Rep:
           5-formyltetrahydrofolate cyclo-ligase - Methanospirillum
           hungatei (strain JF-1 / DSM 864)
          Length = 193

 Score = 38.7 bits (86), Expect = 0.22
 Identities = 19/54 (35%), Positives = 32/54 (59%)
 Frame = +1

Query: 517 FLXSGDRLGHGXGYYDKFITNLRLNPETAPKIVAVAFNCQVVDEVPTTEQDXKV 678
           F  SG R+G+G GYYD+F++    +P    K + VA++ Q V  +P  + D ++
Sbjct: 126 FDRSGGRIGYGAGYYDRFLSE---HPHI--KRIGVAYSVQEVPTIPVQDHDIRM 174


>UniRef50_UPI00006CBD0D Cluster: 5-formyltetrahydrofolate
           cyclo-ligase family protein; n=1; Tetrahymena
           thermophila SB210|Rep: 5-formyltetrahydrofolate
           cyclo-ligase family protein - Tetrahymena thermophila
           SB210
          Length = 186

 Score = 38.3 bits (85), Expect = 0.29
 Identities = 16/45 (35%), Positives = 26/45 (57%)
 Frame = +1

Query: 535 RLGHGXGYYDKFITNLRLNPETAPKIVAVAFNCQVVDEVPTTEQD 669
           R+G G G++D+ I   + N +   K V + F CQ + ++P  EQD
Sbjct: 128 RIGFGGGHFDRTIKYFKEN-QIKLKFVGIGFQCQYIQDLPAEEQD 171


>UniRef50_Q67Q66 Cluster: 5-formyltetrahydrofolate cyclo-ligase;
           n=1; Symbiobacterium thermophilum|Rep:
           5-formyltetrahydrofolate cyclo-ligase - Symbiobacterium
           thermophilum
          Length = 197

 Score = 38.3 bits (85), Expect = 0.29
 Identities = 31/126 (24%), Positives = 53/126 (42%), Gaps = 1/126 (0%)
 Frame = +2

Query: 134 AKALLRNEIAAKIAALTNEEKKRQSQIVYEKVINHSWYKSSSRIALYMSTENEIDTAPLI 313
           +K  LR  + A   AL   E+ R S      V+    +  +  + LY+    E+DTA L 
Sbjct: 4   SKQELRRRMIAARQALDPAERARLSGRAQRAVLAAPEWARARTVLLYIPVRGEVDTAALA 63

Query: 314 KHIQARGAAAFVPQY-AGGRMRMLHLETGDEQTMPKTKHGISQHGKDQARDDALETGGLD 490
              +  G    +P+     R   LH   G  + + +  +GI +   D  ++D      +D
Sbjct: 64  AAGRQAGKRLLLPRVERAERGLRLHRWDGTPEQLVRGAYGIPEPRPDLPQED---PRAVD 120

Query: 491 LIIAPG 508
           L++ PG
Sbjct: 121 LVVVPG 126


>UniRef50_A4J8I3 Cluster: 5-formyltetrahydrofolate cyclo-ligase;
           n=1; Desulfotomaculum reducens MI-1|Rep:
           5-formyltetrahydrofolate cyclo-ligase - Desulfotomaculum
           reducens MI-1
          Length = 191

 Score = 38.3 bits (85), Expect = 0.29
 Identities = 21/44 (47%), Positives = 27/44 (61%)
 Frame = +1

Query: 508 GWRFLXSGDRLGHGXGYYDKFITNLRLNPETAPKIVAVAFNCQV 639
           G  F   G+R+G+G GYYD+FI  LR +  T    VA+AF  QV
Sbjct: 125 GTVFDHQGNRMGYGGGYYDRFIPRLRKDAVT----VALAFEFQV 164


>UniRef50_A0Y9S2 Cluster: 5-formyltetrahydrofolate cyclo-ligase
           family protein; n=1; marine gamma proteobacterium
           HTCC2143|Rep: 5-formyltetrahydrofolate cyclo-ligase
           family protein - marine gamma proteobacterium HTCC2143
          Length = 197

 Score = 38.3 bits (85), Expect = 0.29
 Identities = 18/52 (34%), Positives = 28/52 (53%), Gaps = 1/52 (1%)
 Frame = +1

Query: 517 FLXSGDRLGHGXGYYDKFITNLRLNPE-TAPKIVAVAFNCQVVDEVPTTEQD 669
           F   G RLG G G+YD+   N R  P  + P+++ +A +CQ V  +   + D
Sbjct: 129 FDRQGGRLGMGGGFYDRTFANTRSAPAMSKPQLIGLAHHCQEVPSLQLAQWD 180


>UniRef50_Q81LX0 Cluster: 5-formyltetrahydrofolate cyclo-ligase
           family protein; n=11; Bacillus cereus group|Rep:
           5-formyltetrahydrofolate cyclo-ligase family protein -
           Bacillus anthracis
          Length = 192

 Score = 37.9 bits (84), Expect = 0.38
 Identities = 16/60 (26%), Positives = 35/60 (58%)
 Frame = +1

Query: 508 GWRFLXSGDRLGHGXGYYDKFITNLRLNPETAPKIVAVAFNCQVVDEVPTTEQDXKVXEV 687
           G  +   G+R+G+G GYYD+++ + +       K +++A++ Q+V+ +P    D  V ++
Sbjct: 126 GVAYTERGERIGYGGGYYDRYLVHYK------GKTLSLAYSFQMVEHIPVEPFDKNVEKI 179



 Score = 35.1 bits (77), Expect = 2.7
 Identities = 22/74 (29%), Positives = 37/74 (50%), Gaps = 1/74 (1%)
 Frame = +2

Query: 137 KALLRNEIAAKIAALTNEEKKRQS-QIVYEKVINHSWYKSSSRIALYMSTENEIDTAPLI 313
           K  LR +I   + +L+ E     S QIV+       W ++ + I + +S ENE++T P+I
Sbjct: 5   KLRLRKQIIEHMNSLSKERYTTLSEQIVFSLYEQKEWAEAKT-IGITLSMENEVNTYPII 63

Query: 314 KHIQARGAAAFVPQ 355
           +     G    VP+
Sbjct: 64  EKAWKEGKRVVVPK 77


>UniRef50_Q3SFD5 Cluster: 5-formyltetrahydrofolate cyclo-ligase
           family protein; n=1; Thiobacillus denitrificans ATCC
           25259|Rep: 5-formyltetrahydrofolate cyclo-ligase family
           protein - Thiobacillus denitrificans (strain ATCC 25259)
          Length = 199

 Score = 37.9 bits (84), Expect = 0.38
 Identities = 21/58 (36%), Positives = 29/58 (50%), Gaps = 1/58 (1%)
 Frame = +1

Query: 517 FLXSGDRLGHGXGYYDKFITNLRLNPE-TAPKIVAVAFNCQVVDEVPTTEQDXKVXEV 687
           F   G RLG G GYYD  +  ++       P++V VA+ CQ VD +P    D  +  V
Sbjct: 125 FDTDGYRLGMGGGYYDATLAFMQHRRHWRKPRLVGVAYECQRVDTLPHDPWDMPLDAV 182


>UniRef50_A6VUD0 Cluster: 5-formyltetrahydrofolate cyclo-ligase;
           n=2; Marinomonas|Rep: 5-formyltetrahydrofolate
           cyclo-ligase - Marinomonas sp. MWYL1
          Length = 194

 Score = 37.9 bits (84), Expect = 0.38
 Identities = 19/60 (31%), Positives = 30/60 (50%)
 Frame = +1

Query: 517 FLXSGDRLGHGXGYYDKFITNLRLNPETAPKIVAVAFNCQVVDEVPTTEQDXKVXEVXFP 696
           F   G RLG G G+YD+   N R + +  P ++ +A +CQ V  +P    D  +  +  P
Sbjct: 131 FDSKGGRLGMGGGFYDRTFENKRADQK--PLLIGLAHDCQEVKSLPVEGWDVPLQAIITP 188


>UniRef50_A6QH93 Cluster: 5-formyltetrahydrofolate cyclo-ligase;
           n=12; Staphylococcus aureus|Rep:
           5-formyltetrahydrofolate cyclo-ligase - Staphylococcus
           aureus (strain Newman)
          Length = 197

 Score = 37.9 bits (84), Expect = 0.38
 Identities = 31/135 (22%), Positives = 54/135 (40%)
 Frame = +2

Query: 110 MSPIKPNPAKALLRNEIAAKIAALTNEEKKRQSQIVYEKVINHSWYKSSSRIALYMSTEN 289
           ++ +  N  K  +R  I  K+      EK++    +  +      YK ++ IAL +S  +
Sbjct: 12  LNKVGDNVTKNEIRKYILHKMKNFNKAEKRKADTWLRNQFFATEEYKEANAIALVLSFNH 71

Query: 290 EIDTAPLIKHIQARGAAAFVPQYAGGRMRMLHLETGDEQTMPKTKHGISQHGKDQARDDA 469
           E+DT  +I+         FVP     +M  L+ +   ++        +   G        
Sbjct: 72  EVDTFSIIEQALMDHKRIFVP-----KMDYLNHQMTFKEIFNLKDIDVDNKGIYYPTSKG 126

Query: 470 LETGGLDLIIAPGGG 514
             T  LDLI+ PG G
Sbjct: 127 ETTNNLDLIVVPGVG 141


>UniRef50_A1IE08 Cluster: 5-formyltetrahydrofolate cyclo-ligase
           family protein; n=1; Candidatus Desulfococcus oleovorans
           Hxd3|Rep: 5-formyltetrahydrofolate cyclo-ligase family
           protein - Candidatus Desulfococcus oleovorans Hxd3
          Length = 195

 Score = 37.9 bits (84), Expect = 0.38
 Identities = 24/57 (42%), Positives = 30/57 (52%)
 Frame = +1

Query: 508 GWRFLXSGDRLGHGXGYYDKFITNLRLNPETAPKIVAVAFNCQVVDEVPTTEQDXKV 678
           G  F   G R+G G GYYDK I  L   P T  K V++AF  Q++ +VP    D  V
Sbjct: 130 GLVFDEKGARIGLGTGYYDKLIPKL---PATTRK-VSLAFEDQIIAQVPKGSIDRHV 182



 Score = 37.5 bits (83), Expect = 0.51
 Identities = 19/81 (23%), Positives = 39/81 (48%)
 Frame = +2

Query: 158 IAAKIAALTNEEKKRQSQIVYEKVINHSWYKSSSRIALYMSTENEIDTAPLIKHIQARGA 337
           +  KI A T +E  ++S+ +  ++   + +  +  + +Y++   E+DT  +IKH  +   
Sbjct: 15  VVKKIGAFTKDELSQKSRQILTRLFGFANFMEARVVFIYLNKPGEVDTRSIIKHCFSCNK 74

Query: 338 AAFVPQYAGGRMRMLHLETGD 400
            A VP     R  +  L+  D
Sbjct: 75  VAVVPYDDTNRKDLRLLKLND 95


>UniRef50_Q7VRG0 Cluster: Ligase;5-formyltetrahydrofolate
           cycloligase family; n=2; Candidatus Blochmannia|Rep:
           Ligase;5-formyltetrahydrofolate cycloligase family -
           Blochmannia floridanus
          Length = 195

 Score = 37.5 bits (83), Expect = 0.51
 Identities = 20/75 (26%), Positives = 39/75 (52%)
 Frame = +2

Query: 128 NPAKALLRNEIAAKIAALTNEEKKRQSQIVYEKVINHSWYKSSSRIALYMSTENEIDTAP 307
           N  K  +R+ I +   +L   E+ + +Q++  K+IN      ++ I +Y+S + EI T  
Sbjct: 2   NLNKKAIRSYIRSLRQSLNYSEQYKSAQLITNKIINLDCIHKATHIGIYISFDGEIYTDL 61

Query: 308 LIKHIQARGAAAFVP 352
           LIK + +     ++P
Sbjct: 62  LIKFLLSMKKKIYIP 76


>UniRef50_Q3AS61 Cluster: 5-formyltetrahydrofolate cyclo-ligase,
           putative; n=1; Chlorobium chlorochromatii CaD3|Rep:
           5-formyltetrahydrofolate cyclo-ligase, putative -
           Chlorobium chlorochromatii (strain CaD3)
          Length = 194

 Score = 37.5 bits (83), Expect = 0.51
 Identities = 20/57 (35%), Positives = 29/57 (50%)
 Frame = +1

Query: 517 FLXSGDRLGHGXGYYDKFITNLRLNPETAPKIVAVAFNCQVVDEVPTTEQDXKVXEV 687
           F   G RLG+G GYYD+ +    L+  T P  + +AF+ Q V  +P    D  +  V
Sbjct: 130 FDEKGQRLGYGKGYYDRMLERFTLHHVT-PYCIGLAFSLQQVAALPADFWDKPLDAV 185


>UniRef50_A5P2B9 Cluster: 5-formyltetrahydrofolate cyclo-ligase;
           n=2; Methylobacterium sp. 4-46|Rep:
           5-formyltetrahydrofolate cyclo-ligase - Methylobacterium
           sp. 4-46
          Length = 260

 Score = 37.5 bits (83), Expect = 0.51
 Identities = 25/107 (23%), Positives = 47/107 (43%)
 Frame = +2

Query: 137 KALLRNEIAAKIAALTNEEKKRQSQIVYEKVINHSWYKSSSRIALYMSTENEIDTAPLIK 316
           KA LR E  A+   L    +   S+ + E V+       +  ++ Y    +E+D  PLI 
Sbjct: 69  KASLRREALARRDGLDAAYRAEASRRIAEAVLALPALAGAGLVSAYWPIRSEVDVRPLIA 128

Query: 317 HIQARGAAAFVPQYAGGRMRMLHLETGDEQTMPKTKHGISQHGKDQA 457
            ++ RG A  +PQ       ++  +  ++  +     G+S+ G + A
Sbjct: 129 ALRDRGQAVALPQVTPA--GLVFRQVAEDDALSAGGFGLSEPGPEAA 173


>UniRef50_A1HT82 Cluster: 5-formyltetrahydrofolate cyclo-ligase;
           n=1; Thermosinus carboxydivorans Nor1|Rep:
           5-formyltetrahydrofolate cyclo-ligase - Thermosinus
           carboxydivorans Nor1
          Length = 197

 Score = 37.5 bits (83), Expect = 0.51
 Identities = 21/54 (38%), Positives = 27/54 (50%)
 Frame = +1

Query: 508 GWRFLXSGDRLGHGXGYYDKFITNLRLNPETAPKIVAVAFNCQVVDEVPTTEQD 669
           G  F   G+RLG G GYYD+F+T            V +A++ QV D VP    D
Sbjct: 129 GVAFDREGNRLGMGAGYYDRFLTR-----ALQALFVGMAWSFQVADAVPAATHD 177


>UniRef50_A0V3Q2 Cluster: 5-formyltetrahydrofolate cyclo-ligase;
           n=1; Clostridium cellulolyticum H10|Rep:
           5-formyltetrahydrofolate cyclo-ligase - Clostridium
           cellulolyticum H10
          Length = 182

 Score = 37.5 bits (83), Expect = 0.51
 Identities = 20/54 (37%), Positives = 32/54 (59%)
 Frame = +1

Query: 508 GWRFLXSGDRLGHGXGYYDKFITNLRLNPETAPKIVAVAFNCQVVDEVPTTEQD 669
           G  F  + +R+G+G GYYD+F   L+L      K V +AF+ Q++ ++P  E D
Sbjct: 120 GCAFDLNRNRMGYGAGYYDRF---LKLISHNCLK-VGIAFDFQIMGKIPCNELD 169


>UniRef50_Q1DNE6 Cluster: Putative uncharacterized protein; n=2;
           Pezizomycotina|Rep: Putative uncharacterized protein -
           Coccidioides immitis
          Length = 233

 Score = 37.5 bits (83), Expect = 0.51
 Identities = 24/63 (38%), Positives = 30/63 (47%), Gaps = 6/63 (9%)
 Frame = +1

Query: 508 GWRFLXSGDRLGHGXGYYDKFITNLR---LNPETAPKIVAVAFNCQVV---DEVPTTEQD 669
           G  F  S  RLGHG GYYD F    R    +    P + A+A   Q++   + VP  EQD
Sbjct: 157 GLAFDESFGRLGHGKGYYDHFFMRCRDDTTSTSRKPYLAALALQEQILPPPERVPAGEQD 216

Query: 670 XKV 678
             V
Sbjct: 217 YPV 219


>UniRef50_Q7NBA0 Cluster: Putative uncharacterized protein; n=1;
           Mycoplasma gallisepticum|Rep: Putative uncharacterized
           protein - Mycoplasma gallisepticum
          Length = 186

 Score = 37.1 bits (82), Expect = 0.67
 Identities = 16/51 (31%), Positives = 30/51 (58%)
 Frame = +1

Query: 535 RLGHGXGYYDKFITNLRLNPETAPKIVAVAFNCQVVDEVPTTEQDXKVXEV 687
           RLGHG GYYD+F  NL+ +       ++VA++  + ++    + D K+ ++
Sbjct: 133 RLGHGKGYYDRFFNNLKYSNYK----ISVAYDFMLNNQFQAQDHDVKIDKI 179


>UniRef50_Q73P08 Cluster: 5-formyltetrahydrofolate cyclo-ligase
           family protein; n=1; Treponema denticola|Rep:
           5-formyltetrahydrofolate cyclo-ligase family protein -
           Treponema denticola
          Length = 229

 Score = 37.1 bits (82), Expect = 0.67
 Identities = 19/58 (32%), Positives = 31/58 (53%), Gaps = 1/58 (1%)
 Frame = +1

Query: 508 GWRFLXSGDRLGHGXGYYDKFITNLRLNPETAPKIVA-VAFNCQVVDEVPTTEQDXKV 678
           G  F   G+R+G G G+YD+F   L  + +     +A + F+ Q++D +P  E D  V
Sbjct: 158 GRAFSKKGERMGRGGGFYDRFFEKLFKSIKKEEVCLAGLCFSGQILDTIPMGEFDHPV 215


>UniRef50_Q5PAS2 Cluster: 5-formyltetrahydrofolate cyclo-ligase;
           n=2; Anaplasma|Rep: 5-formyltetrahydrofolate
           cyclo-ligase - Anaplasma marginale (strain St. Maries)
          Length = 178

 Score = 37.1 bits (82), Expect = 0.67
 Identities = 21/54 (38%), Positives = 29/54 (53%)
 Frame = +1

Query: 517 FLXSGDRLGHGXGYYDKFITNLRLNPETAPKIVAVAFNCQVVDEVPTTEQDXKV 678
           F  S +RLG G GYYD  I   R +       + VA+N Q+  ++P TE D K+
Sbjct: 109 FDRSLNRLGFGGGYYDYTIAFFRRSFRCL--CIGVAYNAQLHHKIPVTEHDQKL 160


>UniRef50_Q2G6W2 Cluster: 5-formyltetrahydrofolate cyclo-ligase
           precursor; n=3; Sphingomonadales|Rep:
           5-formyltetrahydrofolate cyclo-ligase precursor -
           Novosphingobium aromaticivorans (strain DSM 12444)
          Length = 195

 Score = 37.1 bits (82), Expect = 0.67
 Identities = 20/60 (33%), Positives = 30/60 (50%)
 Frame = +1

Query: 517 FLXSGDRLGHGXGYYDKFITNLRLNPETAPKIVAVAFNCQVVDEVPTTEQDXKVXEVXFP 696
           F   G RLG G G+YD++I         A   + +A++CQ+VD +P    D  +  V  P
Sbjct: 130 FDAEGGRLGQGGGHYDRWI-----EAHPAAVRIGLAWDCQLVDRLPRETHDRALHAVVTP 184


>UniRef50_A4B8C7 Cluster: 5-formyltetrahydrofolate cyclo-ligase;
           n=17; Gammaproteobacteria|Rep: 5-formyltetrahydrofolate
           cyclo-ligase - Alteromonas macleodii 'Deep ecotype'
          Length = 229

 Score = 37.1 bits (82), Expect = 0.67
 Identities = 22/71 (30%), Positives = 35/71 (49%), Gaps = 7/71 (9%)
 Frame = +1

Query: 517 FLXSGDRLGHGXGYYDKFI--TNLRLNPE-----TAPKIVAVAFNCQVVDEVPTTEQDXK 675
           F  +G+RLG G GYYD+ +  T   + P+       PK+V +A + Q V+ +P    D  
Sbjct: 153 FDTNGNRLGMGGGYYDRTLAFTQRNVYPQKNISSNKPKLVGIAHDMQEVEALPVASWDVP 212

Query: 676 VXEVXFPXXXL 708
           +  +  P   L
Sbjct: 213 LDAIVTPTRTL 223


>UniRef50_A1S972 Cluster: 5-formyltetrahydrofolate cyclo-ligase
           family protein; n=1; Shewanella amazonensis SB2B|Rep:
           5-formyltetrahydrofolate cyclo-ligase family protein -
           Shewanella amazonensis (strain ATCC BAA-1098 / SB2B)
          Length = 228

 Score = 37.1 bits (82), Expect = 0.67
 Identities = 20/68 (29%), Positives = 35/68 (51%)
 Frame = +1

Query: 517 FLXSGDRLGHGXGYYDKFITNLRLNPETAPKIVAVAFNCQVVDEVPTTEQDXKVXEVXFP 696
           F  SG+RLG G G+YD+ +  L   P++  +++ +A +CQ +  +P    D  +  +  P
Sbjct: 163 FDDSGNRLGMGGGFYDRTLAQL---PDST-RVIGLAHDCQRLPALPVEAWDVPLTTIVTP 218

Query: 697 XXXLXLXP 720
                L P
Sbjct: 219 SRIHRLPP 226



 Score = 34.3 bits (75), Expect = 4.7
 Identities = 18/80 (22%), Positives = 39/80 (48%)
 Frame = +2

Query: 113 SPIKPNPAKALLRNEIAAKIAALTNEEKKRQSQIVYEKVINHSWYKSSSRIALYMSTENE 292
           S I  N +++ +R  + A    L+ + +   +    + ++       + R+ALY+  + E
Sbjct: 32  SGISANSSRSAIRKHVRALRRTLSGDVQTAAAIQAAQHLLTE--LADARRVALYLENDGE 89

Query: 293 IDTAPLIKHIQARGAAAFVP 352
           I T PLI+ +  +G   ++P
Sbjct: 90  ISTRPLIEALWQQGVEVYLP 109


>UniRef50_A1BG38 Cluster: 5-formyltetrahydrofolate cyclo-ligase;
           n=1; Chlorobium phaeobacteroides DSM 266|Rep:
           5-formyltetrahydrofolate cyclo-ligase - Chlorobium
           phaeobacteroides (strain DSM 266)
          Length = 216

 Score = 37.1 bits (82), Expect = 0.67
 Identities = 17/47 (36%), Positives = 26/47 (55%)
 Frame = +1

Query: 529 GDRLGHGXGYYDKFITNLRLNPETAPKIVAVAFNCQVVDEVPTTEQD 669
           G RLG+G G+YD+F + L    E  P  + +AF  Q++  +P    D
Sbjct: 152 GYRLGYGKGFYDRFFSRL-AKAECNPLRIGLAFYMQILPRIPVDPWD 197


>UniRef50_Q8RF22 Cluster: 5-formyltetrahydrofolate cyclo-ligase;
           n=3; Fusobacterium nucleatum|Rep:
           5-formyltetrahydrofolate cyclo-ligase - Fusobacterium
           nucleatum subsp. nucleatum
          Length = 181

 Score = 36.7 bits (81), Expect = 0.88
 Identities = 21/58 (36%), Positives = 31/58 (53%), Gaps = 1/58 (1%)
 Frame = +1

Query: 508 GWRFLXSGDRLGHGXGYYDKFITNLRLNPETAPKIVAVAFNCQVVDE-VPTTEQDXKV 678
           G  F    +R+G G GYYD+F        +   K +A+AF  Q++DE + T + D KV
Sbjct: 118 GVAFDRDKNRVGFGRGYYDRFFVK-----QPNAKKIAIAFEKQIIDEGIETDKYDKKV 170


>UniRef50_Q44SK2 Cluster: 5-formyltetrahydrofolate cyclo-ligase;
           n=1; Chlorobium limicola DSM 245|Rep:
           5-formyltetrahydrofolate cyclo-ligase - Chlorobium
           limicola DSM 245
          Length = 195

 Score = 36.7 bits (81), Expect = 0.88
 Identities = 17/47 (36%), Positives = 27/47 (57%)
 Frame = +1

Query: 529 GDRLGHGXGYYDKFITNLRLNPETAPKIVAVAFNCQVVDEVPTTEQD 669
           G R+G+G G+YD+F+  L  + +  P    +AF  Q+V E+P    D
Sbjct: 134 GCRMGYGMGFYDRFLAEL-ASHKCFPCRAGLAFRLQIVPELPCDSWD 179


>UniRef50_Q2BL70 Cluster: Putative uncharacterized protein; n=1;
           Neptuniibacter caesariensis|Rep: Putative
           uncharacterized protein - Neptuniibacter caesariensis
          Length = 194

 Score = 36.7 bits (81), Expect = 0.88
 Identities = 18/69 (26%), Positives = 34/69 (49%)
 Frame = +2

Query: 146 LRNEIAAKIAALTNEEKKRQSQIVYEKVINHSWYKSSSRIALYMSTENEIDTAPLIKHIQ 325
           LR +I +   +LT  ++   +Q +   +     ++ +  IA+Y+  + EID  PLIK   
Sbjct: 7   LRKQIRSLRRSLTPSQQNTAAQALLRNMRTRQDFRRAKSIAMYLPNDGEIDPTPLIKLCW 66

Query: 326 ARGAAAFVP 352
             G   ++P
Sbjct: 67  KLGKEVYLP 75


>UniRef50_Q1VME8 Cluster: 5-formyltetrahydrofolate cyclo-ligase;
           n=1; Psychroflexus torquis ATCC 700755|Rep:
           5-formyltetrahydrofolate cyclo-ligase - Psychroflexus
           torquis ATCC 700755
          Length = 184

 Score = 36.7 bits (81), Expect = 0.88
 Identities = 17/51 (33%), Positives = 29/51 (56%)
 Frame = +1

Query: 535 RLGHGXGYYDKFITNLRLNPETAPKIVAVAFNCQVVDEVPTTEQDXKVXEV 687
           RLG+G GYYDK++ N  +        + VAF+ Q   ++P +  D K+ ++
Sbjct: 125 RLGYGKGYYDKYLKNC-IKKNKKIFTIGVAFSFQKYKKLPISNFDVKLDQI 174


>UniRef50_Q1FEZ7 Cluster: 5-formyltetrahydrofolate cyclo-ligase;
           n=1; Clostridium phytofermentans ISDg|Rep:
           5-formyltetrahydrofolate cyclo-ligase - Clostridium
           phytofermentans ISDg
          Length = 190

 Score = 36.7 bits (81), Expect = 0.88
 Identities = 20/53 (37%), Positives = 32/53 (60%)
 Frame = +1

Query: 508 GWRFLXSGDRLGHGXGYYDKFITNLRLNPETAPKIVAVAFNCQVVDEVPTTEQ 666
           G  F   G+R+G+G GYYD++      +P    K VA+A++ Q +++V  TEQ
Sbjct: 124 GLAFDLMGNRIGYGGGYYDRYFIE---HPNPNLKKVAIAYDFQ-IEKVLQTEQ 172


>UniRef50_Q0KWG0 Cluster: 5-formyltetrahydrofolate cyclo-ligase;
           n=4; Shewanella baltica|Rep: 5-formyltetrahydrofolate
           cyclo-ligase - Shewanella baltica OS195
          Length = 235

 Score = 36.7 bits (81), Expect = 0.88
 Identities = 19/60 (31%), Positives = 30/60 (50%)
 Frame = +1

Query: 529 GDRLGHGXGYYDKFITNLRLNPETAPKIVAVAFNCQVVDEVPTTEQDXKVXEVXFPXXXL 708
           G+R+G G GYYD+ + N +L  +  P  +  A +CQ V  +P    D  +  +  P   L
Sbjct: 176 GNRMGMGGGYYDRTLANWQLKGKPLP--MGYAHDCQQVVSLPCEHWDVPLPFIITPSRVL 233



 Score = 35.9 bits (79), Expect = 1.5
 Identities = 27/123 (21%), Positives = 57/123 (46%), Gaps = 3/123 (2%)
 Frame = +2

Query: 146 LRNEIAAKIAALTNEEKKRQSQIVYEKVINHSWYKSSSRIALYMSTENEIDTAPLIKHIQ 325
           LR  I     +L+  E+ + S    +++++    +++  +ALY++ + E+ T PLI  + 
Sbjct: 50  LRKSIRTARKSLSETEQIQASLSASQRMLDALQAQNAQHVALYLTHDGELATPPLIAALW 109

Query: 326 ARGAAAFVPQ---YAGGRMRMLHLETGDEQTMPKTKHGISQHGKDQARDDALETGGLDLI 496
             G   ++P+   +  G++  LH     +  M   + GI +   D      +    LD++
Sbjct: 110 QLGIRTYLPRLHPFNAGQLLFLHYSA--DTPMQANQFGILEPKLDVRA--IIPVTELDVV 165

Query: 497 IAP 505
           I P
Sbjct: 166 ITP 168


>UniRef50_A7HUZ2 Cluster: 5-formyltetrahydrofolate cyclo-ligase;
           n=1; Parvibaculum lavamentivorans DS-1|Rep:
           5-formyltetrahydrofolate cyclo-ligase - Parvibaculum
           lavamentivorans DS-1
          Length = 199

 Score = 36.7 bits (81), Expect = 0.88
 Identities = 18/50 (36%), Positives = 27/50 (54%)
 Frame = +1

Query: 529 GDRLGHGXGYYDKFITNLRLNPETAPKIVAVAFNCQVVDEVPTTEQDXKV 678
           G RLG+G GYYD+ +  LR         V VAF+ Q   ++P  + D ++
Sbjct: 130 GRRLGYGGGYYDRTLAALR-EDRAGVLAVGVAFSAQEAQDLPEEQFDERL 178


>UniRef50_A7DEJ5 Cluster: 5-formyltetrahydrofolate cyclo-ligase;
           n=2; Methylobacterium extorquens PA1|Rep:
           5-formyltetrahydrofolate cyclo-ligase - Methylobacterium
           extorquens PA1
          Length = 262

 Score = 36.7 bits (81), Expect = 0.88
 Identities = 19/51 (37%), Positives = 26/51 (50%)
 Frame = +1

Query: 517 FLXSGDRLGHGXGYYDKFITNLRLNPETAPKIVAVAFNCQVVDEVPTTEQD 669
           F  +G R+G+G GYYD+ I  L  N       V +AF+ Q +  VP    D
Sbjct: 196 FDRAGQRIGYGAGYYDQAIERLSKNGPVL--TVGIAFSVQEIAHVPAEPHD 244


>UniRef50_P40099 Cluster: 5-formyltetrahydrofolate cyclo-ligase;
           n=2; Saccharomyces cerevisiae|Rep:
           5-formyltetrahydrofolate cyclo-ligase - Saccharomyces
           cerevisiae (Baker's yeast)
          Length = 211

 Score = 36.7 bits (81), Expect = 0.88
 Identities = 17/51 (33%), Positives = 26/51 (50%), Gaps = 1/51 (1%)
 Frame = +1

Query: 520 LXSGDRLGHGXGYYDKFITNLR-LNPETAPKIVAVAFNCQVVDEVPTTEQD 669
           + +G R+GHG GYYD F    + L+    P +V +    QV   +P  + D
Sbjct: 144 IKTGARMGHGAGYYDDFFQRYKILHEGQKPLLVGLCLMEQVASPIPLEKHD 194



 Score = 35.1 bits (77), Expect = 2.7
 Identities = 23/74 (31%), Positives = 38/74 (51%), Gaps = 1/74 (1%)
 Frame = +2

Query: 137 KALLRNEIAAKIAALTNEEKKRQSQIVYEKVINHSWYKSSSRIALYMSTE-NEIDTAPLI 313
           K LLR +I   I AL  +    +S  + + V +     +S R+A YMS +  E+ T  +I
Sbjct: 4   KQLLRRQIKRVINALDYDIIAAESHTISQAVRSLIASANSRRVACYMSMDKGEVTTGEII 63

Query: 314 KHIQARGAAAFVPQ 355
           K++   G   F+P+
Sbjct: 64  KNLFQDGQEVFLPR 77


>UniRef50_Q8DC92 Cluster: 5-formyltetrahydrofolate cyclo-ligase;
           n=5; Vibrio|Rep: 5-formyltetrahydrofolate cyclo-ligase -
           Vibrio vulnificus
          Length = 199

 Score = 36.3 bits (80), Expect = 1.2
 Identities = 18/60 (30%), Positives = 30/60 (50%)
 Frame = +1

Query: 517 FLXSGDRLGHGXGYYDKFITNLRLNPETAPKIVAVAFNCQVVDEVPTTEQDXKVXEVXFP 696
           F  +G RLG G GYYD+ +           K + +A +CQ V+++P    D  + ++  P
Sbjct: 131 FDSTGQRLGMGGGYYDRTLERW-FRTGLGAKPIGIAHDCQHVEQLPCEVWDIPLPKIVTP 189



 Score = 35.9 bits (79), Expect = 1.5
 Identities = 24/87 (27%), Positives = 43/87 (49%), Gaps = 3/87 (3%)
 Frame = +2

Query: 254 SSRIALYMSTENEIDTAPLIKHIQARGAAAFVP---QYAGGRMRMLHLETGDEQTMPKTK 424
           +  IALY+S + E+DT PLI+ +   G   ++P    ++ G++  LH     +  +   +
Sbjct: 45  AQHIALYLSADGELDTKPLIEWLWELGKQVYLPVIHPFSKGQLLFLHYHRHTD--LIYNR 102

Query: 425 HGISQHGKDQARDDALETGGLDLIIAP 505
           +GI +   D+     +    LDLI  P
Sbjct: 103 YGILEPKLDKRH--IIPLAELDLICTP 127


>UniRef50_Q5QVB4 Cluster: 5-formyltetrahydrofolate cyclo-ligase
           family protein; n=2; Idiomarina|Rep:
           5-formyltetrahydrofolate cyclo-ligase family protein -
           Idiomarina loihiensis
          Length = 195

 Score = 36.3 bits (80), Expect = 1.2
 Identities = 18/60 (30%), Positives = 29/60 (48%)
 Frame = +1

Query: 517 FLXSGDRLGHGXGYYDKFITNLRLNPETAPKIVAVAFNCQVVDEVPTTEQDXKVXEVXFP 696
           F  +G+RLG G GYYD+ +             + +++N Q V+ +P    D  + EV  P
Sbjct: 130 FDQNGNRLGMGGGYYDRTLAQWHNGNRPNLFPIGLSYNQQQVEHIPVESWDIPLPEVITP 189


>UniRef50_Q0EWY4 Cluster: 5-formyltetrahydrofolate cyclo-ligase
           family protein; n=1; Mariprofundus ferrooxydans
           PV-1|Rep: 5-formyltetrahydrofolate cyclo-ligase family
           protein - Mariprofundus ferrooxydans PV-1
          Length = 190

 Score = 36.3 bits (80), Expect = 1.2
 Identities = 17/47 (36%), Positives = 27/47 (57%)
 Frame = +1

Query: 529 GDRLGHGXGYYDKFITNLRLNPETAPKIVAVAFNCQVVDEVPTTEQD 669
           G+RLG G G +D ++   R    +  +++ +AF+CQ V EVP    D
Sbjct: 129 GNRLGMGKGCFDFWLAQYR---SSIDQVIGLAFSCQQVAEVPAERHD 172


>UniRef50_A4B9S4 Cluster: Putative carbon-nitrogen ligase; n=1;
           Reinekea sp. MED297|Rep: Putative carbon-nitrogen ligase
           - Reinekea sp. MED297
          Length = 196

 Score = 36.3 bits (80), Expect = 1.2
 Identities = 17/101 (16%), Positives = 48/101 (47%)
 Frame = +2

Query: 137 KALLRNEIAAKIAALTNEEKKRQSQIVYEKVINHSWYKSSSRIALYMSTENEIDTAPLIK 316
           K  LR ++  +  +L+ + +++    V E+++N++ +   +++A+Y++ + E+D    + 
Sbjct: 7   KQQLRRDLRQRRQSLSAQVQEQARYAVVEQLLNNALFPLPAKVAVYIAQDGELDLCAFVA 66

Query: 317 HIQARGAAAFVPQYAGGRMRMLHLETGDEQTMPKTKHGISQ 439
               RG   ++P     +  M       +  +   + GI +
Sbjct: 67  LCWERGIEVYLPVLHADKPEMWFAGYQPDSALTPNRFGIPE 107


>UniRef50_A3VP85 Cluster: 5-formyltetrahydrofolate cyclo-ligase;
           n=1; Parvularcula bermudensis HTCC2503|Rep:
           5-formyltetrahydrofolate cyclo-ligase - Parvularcula
           bermudensis HTCC2503
          Length = 159

 Score = 36.3 bits (80), Expect = 1.2
 Identities = 18/47 (38%), Positives = 24/47 (51%)
 Frame = +1

Query: 529 GDRLGHGXGYYDKFITNLRLNPETAPKIVAVAFNCQVVDEVPTTEQD 669
           G RLGHG GYYD+ ++ LR     A   +   +  QV+D  P    D
Sbjct: 94  GARLGHGGGYYDRTLSALRTEGPGA-LAIGYGYEGQVMDRFPVETHD 139



 Score = 34.3 bits (75), Expect = 4.7
 Identities = 16/32 (50%), Positives = 19/32 (59%)
 Frame = +2

Query: 257 SRIALYMSTENEIDTAPLIKHIQARGAAAFVP 352
           S IALY     E+DTAPL K +  RG A  +P
Sbjct: 10  SAIALYAPKGQELDTAPLAKRLSERGHAILLP 41


>UniRef50_A0NJT9 Cluster: 5-formyltetrahydrofolate cyclo-ligase;
           n=2; Oenococcus oeni|Rep: 5-formyltetrahydrofolate
           cyclo-ligase - Oenococcus oeni ATCC BAA-1163
          Length = 182

 Score = 36.3 bits (80), Expect = 1.2
 Identities = 16/63 (25%), Positives = 34/63 (53%)
 Frame = +1

Query: 508 GWRFLXSGDRLGHGXGYYDKFITNLRLNPETAPKIVAVAFNCQVVDEVPTTEQDXKVXEV 687
           G  F  SG RLG G G+YD+++       + + + V++    Q+++ +P  + D ++ ++
Sbjct: 124 GLAFTKSGKRLGFGAGFYDRYLA------DYSGRTVSLVLKDQLLENIPNDKLDIRIKKI 177

Query: 688 XFP 696
             P
Sbjct: 178 LTP 180



 Score = 35.9 bits (79), Expect = 1.5
 Identities = 19/79 (24%), Positives = 40/79 (50%)
 Frame = +2

Query: 137 KALLRNEIAAKIAALTNEEKKRQSQIVYEKVINHSWYKSSSRIALYMSTENEIDTAPLIK 316
           K  LR +   ++ +   ++KK QS ++Y+ +   + + +S  IA+ +S   E++T P++K
Sbjct: 7   KQKLRRQQKKRLDSYDPDDKKDQSILLYQALFESNDWLNSETIAVTLSLPLELNTKPIVK 66

Query: 317 HIQARGAAAFVPQYAGGRM 373
                     VP+    +M
Sbjct: 67  QAWELDKRVLVPKIIDKKM 85


>UniRef50_Q4P9A6 Cluster: Putative uncharacterized protein; n=1;
           Ustilago maydis|Rep: Putative uncharacterized protein -
           Ustilago maydis (Smut fungus)
          Length = 254

 Score = 36.3 bits (80), Expect = 1.2
 Identities = 23/70 (32%), Positives = 35/70 (50%), Gaps = 7/70 (10%)
 Frame = +1

Query: 508 GWRFLXSGDRLGHGXGYYDKFITNLR----LNPETAPKIVAVAFNCQVV---DEVPTTEQ 666
           G  F  +G RLGHG GYYD+++T           + P  +A+A   QV+   + VP  E+
Sbjct: 171 GVAFDQTGGRLGHGKGYYDRYLTRAEEWASQCGASPPVTMALALREQVLPASERVPADER 230

Query: 667 DXKVXEVXFP 696
           D  +  +  P
Sbjct: 231 DRVLDGIISP 240


>UniRef50_Q38VZ7 Cluster: 5-formyltetrahydrofolate cyclo-ligase;
           n=1; Lactobacillus sakei subsp. sakei 23K|Rep:
           5-formyltetrahydrofolate cyclo-ligase - Lactobacillus
           sakei subsp. sakei (strain 23K)
          Length = 180

 Score = 35.9 bits (79), Expect = 1.5
 Identities = 35/137 (25%), Positives = 66/137 (48%), Gaps = 2/137 (1%)
 Frame = +2

Query: 137 KALLRNEIAAKIAALTNE--EKKRQSQIVYEKVINHSWYKSSSRIALYMSTENEIDTAPL 310
           K  +R +  A +  L  +   K++Q  I+ +K+I+ + ++S++ I + ++   E+ T P+
Sbjct: 4   KQQVRQQGLAALQRLAQQPANKQQQEAILLQKLIDSAAFQSATVIGMTLNQPIEVATQPI 63

Query: 311 IKHIQARGAAAFVPQYAGGRMRMLHLETGDEQTMPKTKHGISQHGKDQARDDALETGGLD 490
           I+  QA G    VP+    R +M   E      + ++  G+ +    Q   + +     D
Sbjct: 64  IEATQAAGKRIVVPRTLPKR-QMAFYELTPTTVLERSHFGVLE---PQITGEPIVP---D 116

Query: 491 LIIAPGGGVFSXPETGW 541
           L+I P G VFS    GW
Sbjct: 117 LMIVP-GVVFSL--DGW 130


>UniRef50_Q3B454 Cluster: 5-formyltetrahydrofolate cyclo-ligase,
           putative; n=1; Pelodictyon luteolum DSM 273|Rep:
           5-formyltetrahydrofolate cyclo-ligase, putative -
           Pelodictyon luteolum (strain DSM 273) (Chlorobium
           luteolum (strain DSM273))
          Length = 213

 Score = 35.5 bits (78), Expect = 2.0
 Identities = 17/48 (35%), Positives = 27/48 (56%)
 Frame = +1

Query: 526 SGDRLGHGXGYYDKFITNLRLNPETAPKIVAVAFNCQVVDEVPTTEQD 669
           SG RLG+G G+YD+F+  L+ +    P  +   F+ Q+ D +P    D
Sbjct: 142 SGYRLGYGKGFYDRFLARLQ-HMGVRPCRIGFGFSMQLHDRLPCDPWD 188


>UniRef50_Q2J5Q1 Cluster: 5-formyltetrahydrofolate cyclo-ligase;
           n=2; Frankia|Rep: 5-formyltetrahydrofolate cyclo-ligase
           - Frankia sp. (strain CcI3)
          Length = 259

 Score = 35.5 bits (78), Expect = 2.0
 Identities = 20/65 (30%), Positives = 32/65 (49%)
 Frame = +1

Query: 526 SGDRLGHGXGYYDKFITNLRLNPETAPKIVAVAFNCQVVDEVPTTEQDXKVXEVXFPXXX 705
           +G RLG G G YD+ +   R+  +    ++AV  + +V+DE+P    D  V  +  P   
Sbjct: 186 TGRRLGRGGGSYDRVLA--RVGADV--PVIAVLHDQEVLDEIPMESHDHNVKIIITPSRT 241

Query: 706 LXLXP 720
           L   P
Sbjct: 242 LRCEP 246


>UniRef50_A6BE49 Cluster: Putative uncharacterized protein; n=1;
           Dorea longicatena DSM 13814|Rep: Putative
           uncharacterized protein - Dorea longicatena DSM 13814
          Length = 174

 Score = 35.5 bits (78), Expect = 2.0
 Identities = 19/51 (37%), Positives = 29/51 (56%)
 Frame = +1

Query: 535 RLGHGXGYYDKFITNLRLNPETAPKIVAVAFNCQVVDEVPTTEQDXKVXEV 687
           R+G+G G+YDK+   L  +P      +A+AF  Q+  E+P  E D K  +V
Sbjct: 112 RIGYGGGFYDKY---LEKHPNL--HAIAIAFELQMYRELPFEEHDIKPEKV 157


>UniRef50_A4TWG6 Cluster: 5-formyltetrahydrofolate cyclo-ligase;
           n=3; Alphaproteobacteria|Rep: 5-formyltetrahydrofolate
           cyclo-ligase - Magnetospirillum gryphiswaldense
          Length = 200

 Score = 35.5 bits (78), Expect = 2.0
 Identities = 20/51 (39%), Positives = 25/51 (49%)
 Frame = +1

Query: 517 FLXSGDRLGHGXGYYDKFITNLRLNPETAPKIVAVAFNCQVVDEVPTTEQD 669
           F  +G RLG+G GYYD+ +  LR         + VAF  Q V  VP    D
Sbjct: 134 FDAAGYRLGYGGGYYDRTLDQLRRQSHVT--AIGVAFAAQRVGAVPRGPHD 182


>UniRef50_Q75BE9 Cluster: ADL385Cp; n=1; Eremothecium gossypii|Rep:
           ADL385Cp - Ashbya gossypii (Yeast) (Eremothecium
           gossypii)
          Length = 218

 Score = 35.5 bits (78), Expect = 2.0
 Identities = 16/48 (33%), Positives = 26/48 (54%)
 Frame = +1

Query: 526 SGDRLGHGXGYYDKFITNLRLNPETAPKIVAVAFNCQVVDEVPTTEQD 669
           +G RLG G GYYD +++  +      P +V +A + Q++  VP    D
Sbjct: 145 TGARLGRGAGYYDNYVSRTQQLHGRRPLLVGLALSQQLMLHVPLEPHD 192


>UniRef50_Q2B5W6 Cluster: Possible 5-formyltetrahydrofolate
           cyclo-ligase; n=1; Bacillus sp. NRRL B-14911|Rep:
           Possible 5-formyltetrahydrofolate cyclo-ligase -
           Bacillus sp. NRRL B-14911
          Length = 175

 Score = 35.1 bits (77), Expect = 2.7
 Identities = 18/57 (31%), Positives = 28/57 (49%)
 Frame = +1

Query: 508 GWRFLXSGDRLGHGXGYYDKFITNLRLNPETAPKIVAVAFNCQVVDEVPTTEQDXKV 678
           G  +   G RLG G GYYD+++             +++AF  Q+V E+P    D K+
Sbjct: 115 GLAYCSGGLRLGFGGGYYDRWLAGY------GGDTISLAFRMQMVPEMPVEPHDKKI 165


>UniRef50_A7B2U8 Cluster: Putative uncharacterized protein; n=1;
           Ruminococcus gnavus ATCC 29149|Rep: Putative
           uncharacterized protein - Ruminococcus gnavus ATCC 29149
          Length = 179

 Score = 35.1 bits (77), Expect = 2.7
 Identities = 28/112 (25%), Positives = 54/112 (48%), Gaps = 2/112 (1%)
 Frame = +2

Query: 179 LTNEEKKRQSQIVYEKVINHSWYKSSSRIALYMSTENEIDTAPLIKHIQARGAAAFVPQY 358
           LT+ E +  S  + E+V++H  +  +  I  Y+S   E+ T  ++      G    VP+ 
Sbjct: 8   LTDREWETYSDRITEQVVSHPLFVQAKEIWCYVSMGKEVCTEQILVSAWRAGKRTAVPKV 67

Query: 359 AGGR-MRMLHLETGDEQTMPKTKHGISQHGKD-QARDDALETGGLDLIIAPG 508
            G R M+  ++E+ ++  +     GI +  ++ +  D  LE   L L++ PG
Sbjct: 68  TGKREMKFYYIESLND--LETGAFGILEPKEEKKGADCCLEKSDL-LMLVPG 116


>UniRef50_A6L8H7 Cluster: Putative 5-formyltetrahydrofolate
           cyclo-ligase; n=2; Parabacteroides|Rep: Putative
           5-formyltetrahydrofolate cyclo-ligase - Parabacteroides
           distasonis (strain ATCC 8503 / DSM 20701 / NCTC11152)
          Length = 184

 Score = 35.1 bits (77), Expect = 2.7
 Identities = 20/60 (33%), Positives = 31/60 (51%)
 Frame = +1

Query: 508 GWRFLXSGDRLGHGXGYYDKFITNLRLNPETAPKIVAVAFNCQVVDEVPTTEQDXKVXEV 687
           G  F    +R+G G G+YD+ ++ L      APK V + F  Q++ +VP    D K+  V
Sbjct: 124 GVAFDKDKNRMGRGRGFYDRLLSTL-----NAPK-VGICFGFQMIPQVPVEPLDKKMDYV 177


>UniRef50_A6DB91 Cluster: 5-formyltetrahydrofolate cyclo-ligase;
           n=1; Caminibacter mediatlanticus TB-2|Rep:
           5-formyltetrahydrofolate cyclo-ligase - Caminibacter
           mediatlanticus TB-2
          Length = 203

 Score = 35.1 bits (77), Expect = 2.7
 Identities = 20/68 (29%), Positives = 34/68 (50%), Gaps = 3/68 (4%)
 Frame = +2

Query: 188 EEKKRQSQIVYEKVINHSWY---KSSSRIALYMSTENEIDTAPLIKHIQARGAAAFVPQY 358
           +E  + ++ ++ K+I+   Y   K    I L++  ENE D  PLIK ++      FVP  
Sbjct: 16  KENLKINRYLFSKIISKELYNISKEYKNILLFIPLENEADIKPLIKKLRREKKNIFVPFM 75

Query: 359 AGGRMRML 382
            G   +M+
Sbjct: 76  EGLSFKMV 83


>UniRef50_Q2ADA7 Cluster: 5-formyltetrahydrofolate cyclo-ligase;
           n=1; Halothermothrix orenii H 168|Rep:
           5-formyltetrahydrofolate cyclo-ligase - Halothermothrix
           orenii H 168
          Length = 193

 Score = 34.7 bits (76), Expect = 3.6
 Identities = 19/57 (33%), Positives = 28/57 (49%)
 Frame = +1

Query: 517 FLXSGDRLGHGXGYYDKFITNLRLNPETAPKIVAVAFNCQVVDEVPTTEQDXKVXEV 687
           F   G R+G+G GYYD+F+  L  N  T    V   ++  ++D +P    D  V  V
Sbjct: 127 FSRDGYRIGYGGGYYDRFLVKLPDNVLT----VGFTYHALLLDNLPIDRYDQPVDMV 179


>UniRef50_Q1LSJ3 Cluster: 5-formyltetrahydrofolate cyclo-ligase
           family protein; n=1; Baumannia cicadellinicola str. Hc
           (Homalodisca coagulata)|Rep: 5-formyltetrahydrofolate
           cyclo-ligase family protein - Baumannia cicadellinicola
           subsp. Homalodisca coagulata
          Length = 202

 Score = 34.7 bits (76), Expect = 3.6
 Identities = 20/57 (35%), Positives = 31/57 (54%), Gaps = 1/57 (1%)
 Frame = +1

Query: 529 GDRLGHGXGYYDKFITNLRLNPETAPKIVAVAFNCQVVDE-VPTTEQDXKVXEVXFP 696
           G+RLG G G+YD+ + +      T   I  +A++CQ   E +PT + D  + EV  P
Sbjct: 136 GNRLGMGGGFYDRMLYSWYTGEFTFCPI-GLAYDCQYQTEAIPTEKWDIPLPEVITP 191


>UniRef50_Q1GFD0 Cluster: 5-formyltetrahydrofolate cyclo-ligase;
           n=20; Rhodobacterales|Rep: 5-formyltetrahydrofolate
           cyclo-ligase - Silicibacter sp. (strain TM1040)
          Length = 195

 Score = 34.7 bits (76), Expect = 3.6
 Identities = 17/51 (33%), Positives = 28/51 (54%)
 Frame = +1

Query: 517 FLXSGDRLGHGXGYYDKFITNLRLNPETAPKIVAVAFNCQVVDEVPTTEQD 669
           F  +G+RLG+G G+YD+ +   RL  + A   +  AF+ Q  + +P    D
Sbjct: 129 FDAAGNRLGYGGGFYDRTLD--RLRAQRATLAIGFAFDAQEAEGLPLEPTD 177


>UniRef50_Q0BZ02 Cluster: 5-formyltetrahydrofolate cyclo-ligase
           family protein; n=1; Hyphomonas neptunium ATCC
           15444|Rep: 5-formyltetrahydrofolate cyclo-ligase family
           protein - Hyphomonas neptunium (strain ATCC 15444)
          Length = 207

 Score = 34.7 bits (76), Expect = 3.6
 Identities = 17/47 (36%), Positives = 25/47 (53%)
 Frame = +1

Query: 529 GDRLGHGXGYYDKFITNLRLNPETAPKIVAVAFNCQVVDEVPTTEQD 669
           G+RLG+G G+YD  +  LR          A+A+  Q +D+VP    D
Sbjct: 128 GNRLGYGRGHYDAALEKLRAKGRAF--ACAIAYAAQQIDKVPCEPHD 172


>UniRef50_A6DHI6 Cluster: Putative uncharacterized protein; n=1;
           Lentisphaera araneosa HTCC2155|Rep: Putative
           uncharacterized protein - Lentisphaera araneosa HTCC2155
          Length = 181

 Score = 34.7 bits (76), Expect = 3.6
 Identities = 17/60 (28%), Positives = 30/60 (50%)
 Frame = +1

Query: 529 GDRLGHGXGYYDKFITNLRLNPETAPKIVAVAFNCQVVDEVPTTEQDXKVXEVXFPXXXL 708
           G+RLG G G+YD+ +    +  +     V V ++ Q++ EVP  + D  +  +  P   L
Sbjct: 121 GNRLGRGGGFYDRLLAKYSIGVK-----VGVCYDFQLIGEVPKEDHDFTMDFILSPSGLL 175


>UniRef50_A5CEL8 Cluster: 5-Formyltetrahydrofolate cyclo-ligase;
           n=1; Orientia tsutsugamushi Boryong|Rep:
           5-Formyltetrahydrofolate cyclo-ligase - Orientia
           tsutsugamushi (strain Boryong) (Rickettsia
           tsutsugamushi)
          Length = 190

 Score = 34.7 bits (76), Expect = 3.6
 Identities = 20/58 (34%), Positives = 32/58 (55%), Gaps = 1/58 (1%)
 Frame = +1

Query: 508 GWRFLXSGDRLGHGXGYYDKFITNLR-LNPETAPKIVAVAFNCQVVDEVPTTEQDXKV 678
           G  F  +G R+G G GYYD++I+ +R +N       + V F+ Q+ + VP    D K+
Sbjct: 123 GLVFDVAGYRIGFGKGYYDQYISQVRSINSNNI--AIGVCFDVQLRNFVPRELHDQKM 178


>UniRef50_A4SEK3 Cluster: 5-formyltetrahydrofolate cyclo-ligase;
           n=1; Prosthecochloris vibrioformis DSM 265|Rep:
           5-formyltetrahydrofolate cyclo-ligase - Prosthecochloris
           vibrioformis DSM 265
          Length = 200

 Score = 34.7 bits (76), Expect = 3.6
 Identities = 17/47 (36%), Positives = 26/47 (55%)
 Frame = +1

Query: 529 GDRLGHGXGYYDKFITNLRLNPETAPKIVAVAFNCQVVDEVPTTEQD 669
           G RLG G GYYD+F++ L       P  +  A++ Q+ D +P+   D
Sbjct: 132 GRRLGFGKGYYDRFLSRLS-REGFRPWRIGYAYSFQMTDCIPSDPWD 177


>UniRef50_A4F7U0 Cluster: 5-formyltetrahydrofolate cyclo-ligase;
           n=3; Actinomycetales|Rep: 5-formyltetrahydrofolate
           cyclo-ligase - Saccharopolyspora erythraea (strain NRRL
           23338)
          Length = 301

 Score = 34.7 bits (76), Expect = 3.6
 Identities = 22/58 (37%), Positives = 31/58 (53%), Gaps = 2/58 (3%)
 Frame = +1

Query: 529 GDRLGHGXGYYDKFITNLRLNPETAP--KIVAVAFNCQVVDEVPTTEQDXKVXEVXFP 696
           G RLG G GYYD+ +      P  AP   +VAV  + + V+E+P  + D +V  V  P
Sbjct: 241 GVRLGRGAGYYDRSL------PMAAPAAALVAVVRDEEFVEELPGEDHDVRVGAVLTP 292


>UniRef50_A3MYI1 Cluster: Putative uncharacterized protein; n=1;
           Actinobacillus pleuropneumoniae L20|Rep: Putative
           uncharacterized protein - Actinobacillus
           pleuropneumoniae serotype 5b (strain L20)
          Length = 191

 Score = 34.7 bits (76), Expect = 3.6
 Identities = 19/48 (39%), Positives = 28/48 (58%)
 Frame = +1

Query: 526 SGDRLGHGXGYYDKFITNLRLNPETAPKIVAVAFNCQVVDEVPTTEQD 669
           SG+RLG+G G+YD+    L L P+     V +A+  Q V+ +PT   D
Sbjct: 137 SGNRLGYGGGFYDR---TLALTPQAIS--VGLAYPFQFVENLPTEPWD 179


>UniRef50_A4RB99 Cluster: Putative uncharacterized protein; n=2;
            Magnaporthe grisea|Rep: Putative uncharacterized protein
            - Magnaporthe grisea (Rice blast fungus) (Pyricularia
            grisea)
          Length = 1934

 Score = 34.7 bits (76), Expect = 3.6
 Identities = 14/42 (33%), Positives = 23/42 (54%)
 Frame = +2

Query: 233  NHSWYKSSSRIALYMSTENEIDTAPLIKHIQARGAAAFVPQY 358
            + +W+ + S + L   TE +IDT  + +HI +     F PQY
Sbjct: 1721 HETWFNALSYLLLRTETEGQIDTESMAEHITSEDVDEFNPQY 1762


>UniRef50_A7DNA8 Cluster: 5-formyltetrahydrofolate cyclo-ligase;
           n=1; Candidatus Nitrosopumilus maritimus SCM1|Rep:
           5-formyltetrahydrofolate cyclo-ligase - Candidatus
           Nitrosopumilus maritimus SCM1
          Length = 187

 Score = 34.7 bits (76), Expect = 3.6
 Identities = 15/47 (31%), Positives = 29/47 (61%)
 Frame = +1

Query: 529 GDRLGHGXGYYDKFITNLRLNPETAPKIVAVAFNCQVVDEVPTTEQD 669
           G RLG+G G+YD+F++N +++       +++    QVV  +P ++ D
Sbjct: 130 GIRLGYGHGFYDRFLSNHKIS------TISLTLEKQVVKNIPKSDHD 170


>UniRef50_Q89ZW3 Cluster: Putative 5-formyltetrahydrofolate
           cyclo-ligase; n=6; Bacteroides|Rep: Putative
           5-formyltetrahydrofolate cyclo-ligase - Bacteroides
           thetaiotaomicron
          Length = 196

 Score = 34.3 bits (75), Expect = 4.7
 Identities = 19/54 (35%), Positives = 26/54 (48%)
 Frame = +1

Query: 508 GWRFLXSGDRLGHGXGYYDKFITNLRLNPETAPKIVAVAFNCQVVDEVPTTEQD 669
           G  F   G+RLG G GYYD+ +  +      A     + F  Q+V+EVP    D
Sbjct: 121 GVAFDRKGNRLGRGKGYYDRLLPRI-----PAAYKAGICFPFQIVEEVPAEAFD 169


>UniRef50_Q6F1L6 Cluster: 5-formyltetrahydrofolate cyclo-ligase
           family protein; n=1; Mesoplasma florum|Rep:
           5-formyltetrahydrofolate cyclo-ligase family protein -
           Mesoplasma florum (Acholeplasma florum)
          Length = 215

 Score = 34.3 bits (75), Expect = 4.7
 Identities = 19/72 (26%), Positives = 38/72 (52%)
 Frame = +2

Query: 137 KALLRNEIAAKIAALTNEEKKRQSQIVYEKVINHSWYKSSSRIALYMSTENEIDTAPLIK 316
           K  +R +     + L+   K+  ++I+  KV ++    +  + A+Y+STENE +T  +I+
Sbjct: 4   KNQIREKFLKTRSFLSKSYKEEVNKIIERKVNHYIDRYNLEKYAIYLSTENEPNTLNIIE 63

Query: 317 HIQARGAAAFVP 352
               +G   +VP
Sbjct: 64  TSLKKGIEVYVP 75


>UniRef50_Q5ZXY7 Cluster: 5-formyltetrahydrofolate cyclo-ligase;
           n=4; Legionella pneumophila|Rep:
           5-formyltetrahydrofolate cyclo-ligase - Legionella
           pneumophila subsp. pneumophila (strain Philadelphia 1
           /ATCC 33152 / DSM 7513)
          Length = 193

 Score = 34.3 bits (75), Expect = 4.7
 Identities = 31/123 (25%), Positives = 48/123 (39%)
 Frame = +2

Query: 137 KALLRNEIAAKIAALTNEEKKRQSQIVYEKVINHSWYKSSSRIALYMSTENEIDTAPLIK 316
           K  LRN I    + L+   +   S  +  ++ +   Y+ + RIALY +   E+D   L K
Sbjct: 6   KVALRNTIKQVRSKLSVPYRTASSNQICTRIRSLEQYRQAKRIALYFAVNGEVDLTFLWK 65

Query: 317 HIQARGAAAFVPQYAGGRMRMLHLETGDEQTMPKTKHGISQHGKDQARDDALETGGLDLI 496
               +G   + P        +  L           K+ I +   D   + AL    LDLI
Sbjct: 66  SAPLQGKYCYFP-VLNNDSTLSFLPATPSTPFKTNKYDIPE--PDVDIELALPIDELDLI 122

Query: 497 IAP 505
           I P
Sbjct: 123 IMP 125


>UniRef50_Q0VL96 Cluster: 5-formyltetrahydrofolate cyclo-ligase
           family protein; n=1; Alcanivorax borkumensis SK2|Rep:
           5-formyltetrahydrofolate cyclo-ligase family protein -
           Alcanivorax borkumensis (strain SK2 / ATCC 700651 / DSM
           11573)
          Length = 193

 Score = 34.3 bits (75), Expect = 4.7
 Identities = 19/56 (33%), Positives = 30/56 (53%), Gaps = 2/56 (3%)
 Frame = +1

Query: 517 FLXSGDRLGHGXGYYDKFITNLRLNPETAPKIVAVAFNCQVVD--EVPTTEQDXKV 678
           F  +G RLG G GYYD+ +  L   P   P+++A  ++ Q ++  E+P    D  V
Sbjct: 130 FDEAGYRLGMGGGYYDRTLEQLTRYPR-RPRLIAAGYDFQKMEQGELPVAPWDQPV 184


>UniRef50_Q0A5K9 Cluster: 5-formyltetrahydrofolate cyclo-ligase;
           n=1; Alkalilimnicola ehrlichei MLHE-1|Rep:
           5-formyltetrahydrofolate cyclo-ligase - Alkalilimnicola
           ehrlichei (strain MLHE-1)
          Length = 209

 Score = 34.3 bits (75), Expect = 4.7
 Identities = 15/69 (21%), Positives = 36/69 (52%)
 Frame = +2

Query: 146 LRNEIAAKIAALTNEEKKRQSQIVYEKVINHSWYKSSSRIALYMSTENEIDTAPLIKHIQ 325
           +R+ + A+  A     ++  ++ +  +V  H   ++  R+A +M  + E+D  PL++ + 
Sbjct: 15  VRHAMRARRRAQPMAVRRWAARQLARRVARHPLLRNVRRLAAFMPADGEMDPLPLMRRLH 74

Query: 326 ARGAAAFVP 352
            RG   ++P
Sbjct: 75  RRGITLYLP 83



 Score = 33.9 bits (74), Expect = 6.2
 Identities = 19/48 (39%), Positives = 26/48 (54%), Gaps = 1/48 (2%)
 Frame = +1

Query: 529 GDRLGHGXGYYDKFITNL-RLNPETAPKIVAVAFNCQVVDEVPTTEQD 669
           G RLG G G+YD     L R    T P+++ VA++ Q V E+P    D
Sbjct: 140 GGRLGMGGGFYDASFAFLGRWRWRTHPRLLGVAWSFQHVPELPLAPWD 187


>UniRef50_A5ZYS6 Cluster: Putative uncharacterized protein; n=3;
           Bacteria|Rep: Putative uncharacterized protein -
           Ruminococcus obeum ATCC 29174
          Length = 249

 Score = 34.3 bits (75), Expect = 4.7
 Identities = 24/73 (32%), Positives = 33/73 (45%)
 Frame = +1

Query: 451 PSQGRCSRNRWIRSDHSSRGWRFLXSGDRLGHGXGYYDKFITNLRLNPETAPKIVAVAFN 630
           P   R    +W  +     G  F     R+G+G G+YD+F   L  +P      VAVAF 
Sbjct: 168 PEPARGEIVQWEEALMIMPGVAFDRQNHRVGYGGGFYDRF---LEKHPYITR--VAVAFE 222

Query: 631 CQVVDEVPTTEQD 669
            Q++ EVP    D
Sbjct: 223 FQMMSEVPVEPTD 235


>UniRef50_A4XKH5 Cluster: 5-formyltetrahydrofolate cyclo-ligase;
           n=1; Caldicellulosiruptor saccharolyticus DSM 8903|Rep:
           5-formyltetrahydrofolate cyclo-ligase -
           Caldicellulosiruptor saccharolyticus (strain ATCC 43494
           / DSM 8903)
          Length = 199

 Score = 34.3 bits (75), Expect = 4.7
 Identities = 22/99 (22%), Positives = 47/99 (47%)
 Frame = +2

Query: 137 KALLRNEIAAKIAALTNEEKKRQSQIVYEKVINHSWYKSSSRIALYMSTENEIDTAPLIK 316
           K  +R  I  +   ++N +K     +VY  +       + + + +YMS   E+DT+ +I 
Sbjct: 3   KKKIRKIIGIRRRLISNFQKLHLDILVYLNLKKFLSKLNFNTVFVYMSLPYEVDTSRIIN 62

Query: 317 HIQARGAAAFVPQYAGGRMRMLHLETGDEQTMPKTKHGI 433
           ++  +G    VP+    ++RM+  E   +  + + + GI
Sbjct: 63  YLSVKGKRICVPKIV-DKIRMIAGEYRKDGKLKRNRFGI 100



 Score = 33.9 bits (74), Expect = 6.2
 Identities = 17/49 (34%), Positives = 28/49 (57%)
 Frame = +1

Query: 532 DRLGHGXGYYDKFITNLRLNPETAPKIVAVAFNCQVVDEVPTTEQDXKV 678
           +R+G G GYYD+F+    + P      V VA++ Q V ++P+   D K+
Sbjct: 129 NRIGFGKGYYDRFLK--EVGPSCLK--VGVAYHFQKVPKIPSERHDVKL 173


>UniRef50_A4ABX0 Cluster: 5-formyltetrahydrofolate cyclo-ligase
           family protein; n=1; Congregibacter litoralis KT71|Rep:
           5-formyltetrahydrofolate cyclo-ligase family protein -
           Congregibacter litoralis KT71
          Length = 217

 Score = 34.3 bits (75), Expect = 4.7
 Identities = 25/112 (22%), Positives = 49/112 (43%)
 Frame = +2

Query: 104 GRMSPIKPNPAKALLRNEIAAKIAALTNEEKKRQSQIVYEKVINHSWYKSSSRIALYMST 283
           G  S   P  ++   R+ +  +  A+     +   + V   + N S++ S+  IALY++ 
Sbjct: 23  GTNSAANPTLSRQACRSHLRQQRRAIAPSYAREAGERVAHYLRNSSFW-SADHIALYLAN 81

Query: 284 ENEIDTAPLIKHIQARGAAAFVPQYAGGRMRMLHLETGDEQTMPKTKHGISQ 439
           + E+D A + +  ++ G   ++P      M      T DE   P  + GI +
Sbjct: 82  DGELDPAVIARAARSSGKHLYLPVITAEAMAFCEWRT-DEPLRP-NRFGIGE 131


>UniRef50_A1CDT2 Cluster: 5-formyltetrahydrofolate cyclo-ligase,
           putative; n=6; Trichocomaceae|Rep:
           5-formyltetrahydrofolate cyclo-ligase, putative -
           Aspergillus clavatus
          Length = 243

 Score = 34.3 bits (75), Expect = 4.7
 Identities = 20/58 (34%), Positives = 29/58 (50%), Gaps = 10/58 (17%)
 Frame = +1

Query: 535 RLGHGXGYYDKFITNL-------RLNPETAPKIVAVAFNCQVV---DEVPTTEQDXKV 678
           RLGHG GYYD F+T         +      P +VA+A   Q++   +E+P  + D  V
Sbjct: 171 RLGHGKGYYDHFLTRYSKKQAKSKTTTSKMPLLVALALKEQMLPLTEEIPVADHDWPV 228


>UniRef50_Q9Z7E3 Cluster: Formyltetrahydrofolate Cycloligase; n=4;
           Chlamydophila|Rep: Formyltetrahydrofolate Cycloligase -
           Chlamydia pneumoniae (Chlamydophila pneumoniae)
          Length = 180

 Score = 33.9 bits (74), Expect = 6.2
 Identities = 15/60 (25%), Positives = 31/60 (51%)
 Frame = +1

Query: 508 GWRFLXSGDRLGHGXGYYDKFITNLRLNPETAPKIVAVAFNCQVVDEVPTTEQDXKVXEV 687
           G  F   G RLG+G G+YD+++     +P  + + + + +  Q +D +P    D  + ++
Sbjct: 121 GLAFDQQGYRLGYGHGFYDRWLAQ---HPYPSIRTIGIGYCEQKIDRLPQESHDIPLSQI 177


>UniRef50_Q2NB11 Cluster: Possible 5-formyltetrahydrofolate
           cyclo-ligase; n=1; Erythrobacter litoralis HTCC2594|Rep:
           Possible 5-formyltetrahydrofolate cyclo-ligase -
           Erythrobacter litoralis (strain HTCC2594)
          Length = 180

 Score = 33.9 bits (74), Expect = 6.2
 Identities = 16/60 (26%), Positives = 34/60 (56%)
 Frame = +1

Query: 517 FLXSGDRLGHGXGYYDKFITNLRLNPETAPKIVAVAFNCQVVDEVPTTEQDXKVXEVXFP 696
           F  +G+RLG G G+YD+++ + +   +     + +A++ Q+V+ +P    D ++  V  P
Sbjct: 119 FTATGERLGQGGGHYDQWLADHQGRTK-----IGLAWDVQLVESLPIEPHDQRLDAVVTP 173


>UniRef50_A7H9A8 Cluster: 5-formyltetrahydrofolate cyclo-ligase;
           n=2; Anaeromyxobacter|Rep: 5-formyltetrahydrofolate
           cyclo-ligase - Anaeromyxobacter sp. Fw109-5
          Length = 205

 Score = 33.9 bits (74), Expect = 6.2
 Identities = 21/57 (36%), Positives = 27/57 (47%)
 Frame = +1

Query: 508 GWRFLXSGDRLGHGXGYYDKFITNLRLNPETAPKIVAVAFNCQVVDEVPTTEQDXKV 678
           G  F   G RLG G GYYD     L   P  A   V +AF+ Q+V  +P    D ++
Sbjct: 137 GVAFSPDGHRLGRGGGYYD---ATLEAMPRAAR--VGLAFDLQLVPALPAEGHDARL 188


>UniRef50_A3V9L4 Cluster: 5-formyltetrahydrofolate cyclo-ligase
           family protein; n=1; Rhodobacterales bacterium
           HTCC2654|Rep: 5-formyltetrahydrofolate cyclo-ligase
           family protein - Rhodobacterales bacterium HTCC2654
          Length = 182

 Score = 33.9 bits (74), Expect = 6.2
 Identities = 19/52 (36%), Positives = 29/52 (55%), Gaps = 1/52 (1%)
 Frame = +1

Query: 517 FLXSGDRLGHGXGYYDKFITNLR-LNPETAPKIVAVAFNCQVVDEVPTTEQD 669
           F  +G+RLG+G G+YD+ +  LR L P  A   +  AF  Q + ++P    D
Sbjct: 118 FDRAGNRLGYGGGFYDRTLAALRALRPTLA---IGYAFAAQELPDLPLEPTD 166


>UniRef50_A3UGX7 Cluster: 5-formyltetrahydrofolate cyclo-ligase;
           n=1; Oceanicaulis alexandrii HTCC2633|Rep:
           5-formyltetrahydrofolate cyclo-ligase - Oceanicaulis
           alexandrii HTCC2633
          Length = 191

 Score = 33.9 bits (74), Expect = 6.2
 Identities = 18/55 (32%), Positives = 31/55 (56%), Gaps = 1/55 (1%)
 Frame = +1

Query: 517 FLXSGDRLGHGXGYYDKFITNLRL-NPETAPKIVAVAFNCQVVDEVPTTEQDXKV 678
           F   G RLG+G G+YD+ +  L+   P T   +V +A+  Q +++VP    D ++
Sbjct: 126 FDLKGRRLGYGGGFYDRTLEALKAQGPLT---VVGLAYEAQRLNKVPAESHDVRM 177


>UniRef50_A1KWH4 Cluster: Putative uncharacterized protein; n=4;
           Neisseria|Rep: Putative uncharacterized protein -
           Neisseria meningitidis serogroup C / serotype 2a (strain
           ATCC 700532 /FAM18)
          Length = 219

 Score = 33.9 bits (74), Expect = 6.2
 Identities = 17/47 (36%), Positives = 23/47 (48%)
 Frame = +1

Query: 529 GDRLGHGXGYYDKFITNLRLNPETAPKIVAVAFNCQVVDEVPTTEQD 669
           G RLG   GYYD  +  ++   +   K V V F CQ+VD +     D
Sbjct: 160 GYRLGQAGGYYDATLAAMKYRLQA--KTVGVGFACQLVDRLSVEAHD 204


>UniRef50_A0NNE7 Cluster: Putative uncharacterized protein; n=1;
           Stappia aggregata IAM 12614|Rep: Putative
           uncharacterized protein - Stappia aggregata IAM 12614
          Length = 192

 Score = 33.9 bits (74), Expect = 6.2
 Identities = 17/48 (35%), Positives = 28/48 (58%), Gaps = 1/48 (2%)
 Frame = +1

Query: 529 GDRLGHGXGYYDKFITNLRLNPETAPKI-VAVAFNCQVVDEVPTTEQD 669
           G R+G+G  +YD  I  L+   ++ P + + +AF+ Q VD VP+   D
Sbjct: 132 GTRIGYGKAFYDTTIAKLQ---QSGPLLCIGLAFSVQEVDHVPSEAHD 176


>UniRef50_Q4JBH0 Cluster: 5-formyltetrahydrofolate cyclo-ligase;
           n=3; Sulfolobaceae|Rep: 5-formyltetrahydrofolate
           cyclo-ligase - Sulfolobus acidocaldarius
          Length = 242

 Score = 33.9 bits (74), Expect = 6.2
 Identities = 22/59 (37%), Positives = 29/59 (49%), Gaps = 3/59 (5%)
 Frame = +1

Query: 529 GDRLGHGXGYYDKFITNLR---LNPETAPKIVAVAFNCQVVDEVPTTEQDXKVXEVXFP 696
           GDR+G G GY +     LR      ET P +V    + Q+VDE+PT   D  V  +  P
Sbjct: 141 GDRVGKGEGYSELEYAILREIGKIDETTP-VVTTIHDIQIVDEIPTEVFDVPVDIIVTP 198


>UniRef50_Q8N3X1 Cluster: Formin-binding protein 4; n=28;
           Eumetazoa|Rep: Formin-binding protein 4 - Homo sapiens
           (Human)
          Length = 1017

 Score = 33.9 bits (74), Expect = 6.2
 Identities = 13/36 (36%), Positives = 16/36 (44%)
 Frame = +3

Query: 666 RPXSGRGXIPXXXIVXXPPPXTPXXXPPQXXPXXAP 773
           +P   RG +P   I+  PPP  P   PP   P   P
Sbjct: 889 QPVQARGAVPTATIIEPPPPPPPPPPPPPPAPKMPP 924


>UniRef50_Q31NN9 Cluster: Putative uncharacterized protein; n=2;
           Synechococcus elongatus|Rep: Putative uncharacterized
           protein - Synechococcus sp. (strain PCC 7942) (Anacystis
           nidulans R2)
          Length = 189

 Score = 33.5 bits (73), Expect = 8.2
 Identities = 20/44 (45%), Positives = 28/44 (63%), Gaps = 2/44 (4%)
 Frame = +1

Query: 529 GDRLGHGXGYYDKFITNLRLNP--ETAPKIVAVAFNCQVVDEVP 654
           G RLG+G GYYD+    LR +P   + P IV VA+  Q++ E+P
Sbjct: 130 GYRLGYGGGYYDR----LRADPAWRSIPAIV-VAYAAQIMSELP 168


>UniRef50_Q2SN29 Cluster: 5-formyltetrahydrofolate cyclo-ligase;
           n=1; Hahella chejuensis KCTC 2396|Rep:
           5-formyltetrahydrofolate cyclo-ligase - Hahella
           chejuensis (strain KCTC 2396)
          Length = 190

 Score = 33.5 bits (73), Expect = 8.2
 Identities = 19/57 (33%), Positives = 29/57 (50%)
 Frame = +1

Query: 517 FLXSGDRLGHGXGYYDKFITNLRLNPETAPKIVAVAFNCQVVDEVPTTEQDXKVXEV 687
           F   G+RLG G GYYD+   + R+  +  PK++  A + Q   E+P    D  +  V
Sbjct: 119 FDKQGNRLGMGGGYYDRTFADRRVIIK-RPKLIGFAHHFQQFPELPHEPWDIPLSAV 174


>UniRef50_Q7D907 Cluster: 5-formyltetrahydrofolate
           cyclo-ligase-related protein; n=18; Mycobacterium|Rep:
           5-formyltetrahydrofolate cyclo-ligase-related protein -
           Mycobacterium tuberculosis
          Length = 195

 Score = 33.5 bits (73), Expect = 8.2
 Identities = 21/64 (32%), Positives = 31/64 (48%)
 Frame = +1

Query: 529 GDRLGHGXGYYDKFITNLRLNPETAPKIVAVAFNCQVVDEVPTTEQDXKVXEVXFPXXXL 708
           G RLG G G+YD+   +LR     A ++VAV    ++VD +P+   D  +     P   L
Sbjct: 133 GVRLGRGRGFYDR---SLRCRDPHA-RLVAVVRTVELVDVLPSEPHDVPMTHALTPERGL 188

Query: 709 XLXP 720
              P
Sbjct: 189 IALP 192


>UniRef50_A4BS87 Cluster: 5-formyltetrahydrofolate cyclo-ligase;
           n=1; Nitrococcus mobilis Nb-231|Rep:
           5-formyltetrahydrofolate cyclo-ligase - Nitrococcus
           mobilis Nb-231
          Length = 210

 Score = 33.5 bits (73), Expect = 8.2
 Identities = 27/125 (21%), Positives = 53/125 (42%), Gaps = 1/125 (0%)
 Frame = +2

Query: 134 AKALLRNEIAAKIAALTNEEKKRQSQIVYEKVINHSWYKSSSRIALYMSTENEIDTAPLI 313
           +KA LR+ +  +   L   E+ R ++ +   +    WY  S RIA Y + + E+D    +
Sbjct: 3   SKAELRHRMRRQRRQLGLCERTRAARQLTAVLRRSRWYHHSHRIACYWAMDGEMDLGAFL 62

Query: 314 KHIQARGAAAFVPQYAGGRMRMLHL-ETGDEQTMPKTKHGISQHGKDQARDDALETGGLD 490
           +     G   ++P       + L   +    + +   + GI +    QA  + +    LD
Sbjct: 63  QRAHQDGRVIYLPVLQKKPTKSLRFYQYRPGERLRANRFGIPEPRPRQA--NRIACRDLD 120

Query: 491 LIIAP 505
           L++ P
Sbjct: 121 LVLVP 125


>UniRef50_A4A1P3 Cluster: Putative uncharacterized protein; n=1;
           Blastopirellula marina DSM 3645|Rep: Putative
           uncharacterized protein - Blastopirellula marina DSM
           3645
          Length = 527

 Score = 33.5 bits (73), Expect = 8.2
 Identities = 29/94 (30%), Positives = 41/94 (43%)
 Frame = +2

Query: 86  YLVQLGGRMSPIKPNPAKALLRNEIAAKIAALTNEEKKRQSQIVYEKVINHSWYKSSSRI 265
           Y    GGR  P K  PA+   ++E   K  A   E KKR   +V  +   H W  +S  +
Sbjct: 139 YFTGHGGRSKPTKEKPAETEKKSEPTEKGDAKEEEPKKRAKPLVNNR--THLW--NSHEM 194

Query: 266 ALYMSTENEIDTAPLIKHIQARGAAAFVPQYAGG 367
            +   TE ++D  P    + A   A  V  Y+GG
Sbjct: 195 TVTEWTE-KLDELP----VDAPVIAVMVQCYSGG 223


>UniRef50_A3K0D8 Cluster: 5-formyltetrahydrofolate cyclo-ligase
           family protein; n=1; Sagittula stellata E-37|Rep:
           5-formyltetrahydrofolate cyclo-ligase family protein -
           Sagittula stellata E-37
          Length = 136

 Score = 33.5 bits (73), Expect = 8.2
 Identities = 17/51 (33%), Positives = 27/51 (52%)
 Frame = +1

Query: 517 FLXSGDRLGHGXGYYDKFITNLRLNPETAPKIVAVAFNCQVVDEVPTTEQD 669
           F  SG RLG+G G+YD+ +  +R    T    +  AF  Q + ++P  + D
Sbjct: 73  FSRSGGRLGYGGGFYDRTLERMRAKRPTL--AIGFAFAGQEMVDLPLEDTD 121


>UniRef50_A2U6F2 Cluster: 5-formyltetrahydrofolate cyclo-ligase
           precursor; n=1; Bacillus coagulans 36D1|Rep:
           5-formyltetrahydrofolate cyclo-ligase precursor -
           Bacillus coagulans 36D1
          Length = 191

 Score = 33.5 bits (73), Expect = 8.2
 Identities = 19/60 (31%), Positives = 30/60 (50%)
 Frame = +1

Query: 508 GWRFLXSGDRLGHGXGYYDKFITNLRLNPETAPKIVAVAFNCQVVDEVPTTEQDXKVXEV 687
           G  F   G R+G G GYYD+F+      P    + V++  +CQ+   VP+   D  V ++
Sbjct: 124 GLVFDKKGFRIGFGGGYYDRFLAGF---PN---QTVSLIHSCQLKAHVPSESYDIPVRQI 177


>UniRef50_A2RHQ0 Cluster: 5-formyltetrahydrofolate cyclo-ligase
           family protein; n=2; Lactococcus lactis|Rep:
           5-formyltetrahydrofolate cyclo-ligase family protein -
           Lactococcus lactis subsp. cremoris (strain MG1363)
          Length = 177

 Score = 33.5 bits (73), Expect = 8.2
 Identities = 26/103 (25%), Positives = 49/103 (47%)
 Frame = +2

Query: 149 RNEIAAKIAALTNEEKKRQSQIVYEKVINHSWYKSSSRIALYMSTENEIDTAPLIKHIQA 328
           R +I   +   ++ EK  Q++ V E++   S +KS+ +IALYMS   E +   L    Q+
Sbjct: 8   RKKILQMLKKFSDYEKGCQNKEVLEQLTASSDWKSAKKIALYMSMPIEFNLTELFD--QS 65

Query: 329 RGAAAFVPQYAGGRMRMLHLETGDEQTMPKTKHGISQHGKDQA 457
                 +P+      R +     D++ + ++K G+ +   D A
Sbjct: 66  DDKEILIPKCL--PQRQMIFAKYDKENLVRSKFGLLEPKSDLA 106


>UniRef50_Q55ZD6 Cluster: Putative uncharacterized protein; n=1;
           Filobasidiella neoformans|Rep: Putative uncharacterized
           protein - Cryptococcus neoformans (Filobasidiella
           neoformans)
          Length = 234

 Score = 33.5 bits (73), Expect = 8.2
 Identities = 17/58 (29%), Positives = 32/58 (55%), Gaps = 3/58 (5%)
 Frame = +1

Query: 532 DRLGHGXGYYDKFITNLRLNPETAPKIVAVAFNCQVV---DEVPTTEQDXKVXEVXFP 696
           +RLG G  YYD+F+ +   +    P ++A+A   Q++   + VPT + D ++  +  P
Sbjct: 168 NRLGRGKAYYDRFLQSY-TSTRPRPLLMAIALEPQILPHGERVPTWDWDFQLDGIISP 224


  Database: uniref50
    Posted date:  Oct 5, 2007 11:19 AM
  Number of letters in database: 575,637,011
  Number of sequences in database:  1,657,284
  
Lambda     K      H
   0.318    0.134    0.401 

Gapped
Lambda     K      H
   0.279   0.0580    0.190 


Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 850,984,444
Number of Sequences: 1657284
Number of extensions: 17104824
Number of successful extensions: 55614
Number of sequences better than 10.0: 188
Number of HSP's better than 10.0 without gapping: 42802
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 51888
length of database: 575,637,011
effective HSP length: 101
effective length of database: 408,251,327
effective search space used: 89407040613
frameshift window, decay const: 40,  0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)

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