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Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= MFBP01_F_L05
         (962 letters)

Database: human 
           237,096 sequences; 76,859,062 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

L38928-1|AAC41945.1|  203|Homo sapiens 5,10-methenyltetrahydrofo...   109   2e-23
BC019921-1|AAH19921.1|  203|Homo sapiens 5,10-methenyltetrahydro...   109   2e-23
BC012417-1|AAH12417.1|  193|Homo sapiens MTHFS protein protein.       106   1e-22
BC037852-1|AAH37852.1|   94|Homo sapiens MTHFS protein protein.        52   4e-06
BX537864-1|CAD97867.1|  270|Homo sapiens hypothetical protein pr...    34   0.89 
BC037404-1|AAH37404.1| 1015|Homo sapiens formin binding protein ...    34   0.89 
AK022987-1|BAB14348.1|  560|Homo sapiens protein ( Homo sapiens ...    34   0.89 
AB023231-1|BAA76858.2| 1050|Homo sapiens KIAA1014 protein protein.     34   0.89 
Z97054-12|CAI42656.1| 3407|Homo sapiens upstream regulatory elem...    32   2.7  
Z97054-10|CAI42654.1| 4374|Homo sapiens upstream regulatory elem...    32   2.7  
Z94044-4|CAI42354.1| 4374|Homo sapiens upstream regulatory eleme...    32   2.7  
DQ097177-1|AAY98258.1| 4374|Homo sapiens Mcl-1 ubiquitin ligase ...    32   2.7  
AY929612-1|AAX24125.1| 4374|Homo sapiens LASU1 protein.                32   2.7  
AY772009-1|AAV90838.1| 4374|Homo sapiens ARF-binding protein 1 p...    32   2.7  
AL592046-4|CAI39581.1| 3407|Homo sapiens upstream regulatory ele...    32   2.7  
AL592046-3|CAI39580.1| 4374|Homo sapiens upstream regulatory ele...    32   2.7  
AB071605-1|BAC06833.1| 3360|Homo sapiens HECT domain protein LAS...    32   2.7  
AB002310-1|BAA20771.2| 3192|Homo sapiens KIAA0312 protein.             32   2.7  

>L38928-1|AAC41945.1|  203|Homo sapiens
           5,10-methenyltetrahydrofolate synthetase protein.
          Length = 203

 Score =  109 bits (261), Expect = 2e-23
 Identities = 56/138 (40%), Positives = 87/138 (63%), Gaps = 3/138 (2%)
 Frame = +2

Query: 110 MSPIKPNPAKALLRNEIAAKIAALTNEEKKRQSQIVYEKVINHSWYKSSSRIALYMSTEN 289
           M+    + AK  LR E+  ++ A++ EE+ RQS+++ +KVI HS Y+ S RI++++S ++
Sbjct: 1   MAAAAVSSAKRSLRGELKQRLRAMSAEERLRQSRVLSQKVIAHSEYQKSKRISIFLSMQD 60

Query: 290 EIDTAPLIKHIQARGAAAFVPQY--AGGRMRMLHLETGDE-QTMPKTKHGISQHGKDQAR 460
           EI+T  +IK I  RG   F+P+Y      M M+ +E+ +E   +PKT   I Q G+   R
Sbjct: 61  EIETEEIIKDIFQRGKICFIPRYRFQSNHMDMVRIESPEEISLLPKTSWNIPQPGEGDVR 120

Query: 461 DDALETGGLDLIIAPGGG 514
           ++AL TGGLDLI  PG G
Sbjct: 121 EEALSTGGLDLIFMPGLG 138



 Score = 51.6 bits (118), Expect = 4e-06
 Identities = 25/62 (40%), Positives = 34/62 (54%)
 Frame = +1

Query: 508 GWRFLXSGDRLGHGXGYYDKFITNLRLNPETAPKIVAVAFNCQVVDEVPTTEQDXKVXEV 687
           G  F   G+RLG G GYYD ++     + E  P  +A+AF  Q+  +VP  E D KV EV
Sbjct: 136 GLGFDKHGNRLGRGKGYYDAYLKRCLQHQEVKPYTLALAFKEQICLQVPVNENDMKVDEV 195

Query: 688 XF 693
            +
Sbjct: 196 LY 197


>BC019921-1|AAH19921.1|  203|Homo sapiens
           5,10-methenyltetrahydrofolate synthetase
           (5-formyltetrahydrofolate cyclo-ligase protein.
          Length = 203

 Score =  109 bits (261), Expect = 2e-23
 Identities = 56/138 (40%), Positives = 87/138 (63%), Gaps = 3/138 (2%)
 Frame = +2

Query: 110 MSPIKPNPAKALLRNEIAAKIAALTNEEKKRQSQIVYEKVINHSWYKSSSRIALYMSTEN 289
           M+    + AK  LR E+  ++ A++ EE+ RQS+++ +KVI HS Y+ S RI++++S ++
Sbjct: 1   MAAAAVSSAKRSLRGELKQRLRAMSAEERLRQSRVLSQKVIAHSEYQKSKRISIFLSMQD 60

Query: 290 EIDTAPLIKHIQARGAAAFVPQY--AGGRMRMLHLETGDE-QTMPKTKHGISQHGKDQAR 460
           EI+T  +IK I  RG   F+P+Y      M M+ +E+ +E   +PKT   I Q G+   R
Sbjct: 61  EIETEEIIKDIFQRGKICFIPRYRFQSNHMDMVRIESPEEISLLPKTSWNIPQPGEGDVR 120

Query: 461 DDALETGGLDLIIAPGGG 514
           ++AL TGGLDLI  PG G
Sbjct: 121 EEALSTGGLDLIFMPGLG 138



 Score = 51.6 bits (118), Expect = 4e-06
 Identities = 25/62 (40%), Positives = 34/62 (54%)
 Frame = +1

Query: 508 GWRFLXSGDRLGHGXGYYDKFITNLRLNPETAPKIVAVAFNCQVVDEVPTTEQDXKVXEV 687
           G  F   G+RLG G GYYD ++     + E  P  +A+AF  Q+  +VP  E D KV EV
Sbjct: 136 GLGFDKHGNRLGRGKGYYDAYLKRCLQHQEVKPYTLALAFKEQICLQVPVNENDMKVDEV 195

Query: 688 XF 693
            +
Sbjct: 196 LY 197


>BC012417-1|AAH12417.1|  193|Homo sapiens MTHFS protein protein.
          Length = 193

 Score =  106 bits (254), Expect = 1e-22
 Identities = 53/126 (42%), Positives = 82/126 (65%), Gaps = 3/126 (2%)
 Frame = +2

Query: 146 LRNEIAAKIAALTNEEKKRQSQIVYEKVINHSWYKSSSRIALYMSTENEIDTAPLIKHIQ 325
           LR E+  ++ A++ EE+ RQS+++ +KVI HS Y+ S RI++++S ++EI+T  +IK I 
Sbjct: 3   LRGELKQRLRAMSAEERLRQSRVLSQKVIAHSEYQKSKRISIFLSMQDEIETEEIIKDIF 62

Query: 326 ARGAAAFVPQY--AGGRMRMLHLETGDE-QTMPKTKHGISQHGKDQARDDALETGGLDLI 496
            RG   F+P+Y      M M+ +E+ +E   +PKT   I Q G+   R++AL TGGLDLI
Sbjct: 63  QRGKICFIPRYRFQSNHMDMVRIESPEEISLLPKTSWNIPQPGEGDVREEALSTGGLDLI 122

Query: 497 IAPGGG 514
             PG G
Sbjct: 123 FMPGLG 128



 Score = 51.6 bits (118), Expect = 4e-06
 Identities = 25/62 (40%), Positives = 34/62 (54%)
 Frame = +1

Query: 508 GWRFLXSGDRLGHGXGYYDKFITNLRLNPETAPKIVAVAFNCQVVDEVPTTEQDXKVXEV 687
           G  F   G+RLG G GYYD ++     + E  P  +A+AF  Q+  +VP  E D KV EV
Sbjct: 126 GLGFDKHGNRLGRGKGYYDAYLKRCLQHQEVKPYTLALAFKEQICLQVPVNENDMKVDEV 185

Query: 688 XF 693
            +
Sbjct: 186 LY 187


>BC037852-1|AAH37852.1|   94|Homo sapiens MTHFS protein protein.
          Length = 94

 Score = 51.6 bits (118), Expect = 4e-06
 Identities = 25/62 (40%), Positives = 34/62 (54%)
 Frame = +1

Query: 508 GWRFLXSGDRLGHGXGYYDKFITNLRLNPETAPKIVAVAFNCQVVDEVPTTEQDXKVXEV 687
           G  F   G+RLG G GYYD ++     + E  P  +A+AF  Q+  +VP  E D KV EV
Sbjct: 27  GLGFDKHGNRLGRGKGYYDAYLKRCLQHQEVKPYTLALAFKEQICLQVPVNENDMKVDEV 86

Query: 688 XF 693
            +
Sbjct: 87  LY 88


>BX537864-1|CAD97867.1|  270|Homo sapiens hypothetical protein
           protein.
          Length = 270

 Score = 33.9 bits (74), Expect = 0.89
 Identities = 13/36 (36%), Positives = 16/36 (44%)
 Frame = +3

Query: 666 RPXSGRGXIPXXXIVXXPPPXTPXXXPPQXXPXXAP 773
           +P   RG +P   I+  PPP  P   PP   P   P
Sbjct: 226 QPVQARGAVPTATIIEPPPPPPPPPPPPPPAPKMPP 261


>BC037404-1|AAH37404.1| 1015|Homo sapiens formin binding protein 4
           protein.
          Length = 1015

 Score = 33.9 bits (74), Expect = 0.89
 Identities = 13/36 (36%), Positives = 16/36 (44%)
 Frame = +3

Query: 666 RPXSGRGXIPXXXIVXXPPPXTPXXXPPQXXPXXAP 773
           +P   RG +P   I+  PPP  P   PP   P   P
Sbjct: 887 QPVQARGAVPTATIIEPPPPPPPPPPPPPPAPKMPP 922


>AK022987-1|BAB14348.1|  560|Homo sapiens protein ( Homo sapiens
           cDNA FLJ12925 fis, clone NT2RP2004710, highly similar to
           Mus musculus formin binding protein 30 mRNA. ).
          Length = 560

 Score = 33.9 bits (74), Expect = 0.89
 Identities = 13/36 (36%), Positives = 16/36 (44%)
 Frame = +3

Query: 666 RPXSGRGXIPXXXIVXXPPPXTPXXXPPQXXPXXAP 773
           +P   RG +P   I+  PPP  P   PP   P   P
Sbjct: 432 QPVQARGAVPTATIIEPPPPPPPPPPPPPPAPKMPP 467


>AB023231-1|BAA76858.2| 1050|Homo sapiens KIAA1014 protein protein.
          Length = 1050

 Score = 33.9 bits (74), Expect = 0.89
 Identities = 13/36 (36%), Positives = 16/36 (44%)
 Frame = +3

Query: 666  RPXSGRGXIPXXXIVXXPPPXTPXXXPPQXXPXXAP 773
            +P   RG +P   I+  PPP  P   PP   P   P
Sbjct: 922  QPVQARGAVPTATIIEPPPPPPPPPPPPPPAPKMPP 957


>Z97054-12|CAI42656.1| 3407|Homo sapiens upstream regulatory element
            binding protein 1 (UREB1) protein.
          Length = 3407

 Score = 32.3 bits (70), Expect = 2.7
 Identities = 15/42 (35%), Positives = 27/42 (64%)
 Frame = +2

Query: 140  ALLRNEIAAKIAALTNEEKKRQSQIVYEKVINHSWYKSSSRI 265
            A++  +IAA+  AL  E++ RQ Q+++E++  HS   + S I
Sbjct: 2116 AVMPPDIAAEAQALRREQEARQRQLMHERLFGHSSTSALSAI 2157


>Z97054-10|CAI42654.1| 4374|Homo sapiens upstream regulatory element
            binding protein 1 (UREB1) protein.
          Length = 4374

 Score = 32.3 bits (70), Expect = 2.7
 Identities = 15/42 (35%), Positives = 27/42 (64%)
 Frame = +2

Query: 140  ALLRNEIAAKIAALTNEEKKRQSQIVYEKVINHSWYKSSSRI 265
            A++  +IAA+  AL  E++ RQ Q+++E++  HS   + S I
Sbjct: 3083 AVMPPDIAAEAQALRREQEARQRQLMHERLFGHSSTSALSAI 3124


>Z94044-4|CAI42354.1| 4374|Homo sapiens upstream regulatory element
            binding protein 1 (UREB1) protein.
          Length = 4374

 Score = 32.3 bits (70), Expect = 2.7
 Identities = 15/42 (35%), Positives = 27/42 (64%)
 Frame = +2

Query: 140  ALLRNEIAAKIAALTNEEKKRQSQIVYEKVINHSWYKSSSRI 265
            A++  +IAA+  AL  E++ RQ Q+++E++  HS   + S I
Sbjct: 3083 AVMPPDIAAEAQALRREQEARQRQLMHERLFGHSSTSALSAI 3124


>DQ097177-1|AAY98258.1| 4374|Homo sapiens Mcl-1 ubiquitin ligase
            protein.
          Length = 4374

 Score = 32.3 bits (70), Expect = 2.7
 Identities = 15/42 (35%), Positives = 27/42 (64%)
 Frame = +2

Query: 140  ALLRNEIAAKIAALTNEEKKRQSQIVYEKVINHSWYKSSSRI 265
            A++  +IAA+  AL  E++ RQ Q+++E++  HS   + S I
Sbjct: 3083 AVMPPDIAAEAQALRREQEARQRQLMHERLFGHSSTSALSAI 3124


>AY929612-1|AAX24125.1| 4374|Homo sapiens LASU1 protein.
          Length = 4374

 Score = 32.3 bits (70), Expect = 2.7
 Identities = 15/42 (35%), Positives = 27/42 (64%)
 Frame = +2

Query: 140  ALLRNEIAAKIAALTNEEKKRQSQIVYEKVINHSWYKSSSRI 265
            A++  +IAA+  AL  E++ RQ Q+++E++  HS   + S I
Sbjct: 3083 AVMPPDIAAEAQALRREQEARQRQLMHERLFGHSSTSALSAI 3124


>AY772009-1|AAV90838.1| 4374|Homo sapiens ARF-binding protein 1
            protein.
          Length = 4374

 Score = 32.3 bits (70), Expect = 2.7
 Identities = 15/42 (35%), Positives = 27/42 (64%)
 Frame = +2

Query: 140  ALLRNEIAAKIAALTNEEKKRQSQIVYEKVINHSWYKSSSRI 265
            A++  +IAA+  AL  E++ RQ Q+++E++  HS   + S I
Sbjct: 3083 AVMPPDIAAEAQALRREQEARQRQLMHERLFGHSSTSALSAI 3124


>AL592046-4|CAI39581.1| 3407|Homo sapiens upstream regulatory element
            binding protein 1 (UREB1) protein.
          Length = 3407

 Score = 32.3 bits (70), Expect = 2.7
 Identities = 15/42 (35%), Positives = 27/42 (64%)
 Frame = +2

Query: 140  ALLRNEIAAKIAALTNEEKKRQSQIVYEKVINHSWYKSSSRI 265
            A++  +IAA+  AL  E++ RQ Q+++E++  HS   + S I
Sbjct: 2116 AVMPPDIAAEAQALRREQEARQRQLMHERLFGHSSTSALSAI 2157


>AL592046-3|CAI39580.1| 4374|Homo sapiens upstream regulatory element
            binding protein 1 (UREB1) protein.
          Length = 4374

 Score = 32.3 bits (70), Expect = 2.7
 Identities = 15/42 (35%), Positives = 27/42 (64%)
 Frame = +2

Query: 140  ALLRNEIAAKIAALTNEEKKRQSQIVYEKVINHSWYKSSSRI 265
            A++  +IAA+  AL  E++ RQ Q+++E++  HS   + S I
Sbjct: 3083 AVMPPDIAAEAQALRREQEARQRQLMHERLFGHSSTSALSAI 3124


>AB071605-1|BAC06833.1| 3360|Homo sapiens HECT domain protein LASU1
            protein.
          Length = 3360

 Score = 32.3 bits (70), Expect = 2.7
 Identities = 15/42 (35%), Positives = 27/42 (64%)
 Frame = +2

Query: 140  ALLRNEIAAKIAALTNEEKKRQSQIVYEKVINHSWYKSSSRI 265
            A++  +IAA+  AL  E++ RQ Q+++E++  HS   + S I
Sbjct: 2069 AVMPPDIAAEAQALRREQEARQRQLMHERLFGHSSTSALSAI 2110


>AB002310-1|BAA20771.2| 3192|Homo sapiens KIAA0312 protein.
          Length = 3192

 Score = 32.3 bits (70), Expect = 2.7
 Identities = 15/42 (35%), Positives = 27/42 (64%)
 Frame = +2

Query: 140  ALLRNEIAAKIAALTNEEKKRQSQIVYEKVINHSWYKSSSRI 265
            A++  +IAA+  AL  E++ RQ Q+++E++  HS   + S I
Sbjct: 1901 AVMPPDIAAEAQALRREQEARQRQLMHERLFGHSSTSALSAI 1942


  Database: human
    Posted date:  Oct 23, 2007  1:18 PM
  Number of letters in database: 76,859,062
  Number of sequences in database:  237,096
  
Lambda     K      H
   0.318    0.134    0.401 

Gapped
Lambda     K      H
   0.279   0.0580    0.190 


Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 131,519,841
Number of Sequences: 237096
Number of extensions: 2971256
Number of successful extensions: 8333
Number of sequences better than 10.0: 18
Number of HSP's better than 10.0 without gapping: 5844
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 7832
length of database: 76,859,062
effective HSP length: 90
effective length of database: 55,520,422
effective search space used: 12769697060
frameshift window, decay const: 40,  0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)

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