Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= MFBP01_F_I13
(991 letters)
Database: uniref50
1,657,284 sequences; 575,637,011 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
UniRef50_Q9Y020 Cluster: 3-dehydroecdysone 3beta-reductase precu... 93 1e-17
UniRef50_Q8WRT0 Cluster: 3-dehydrecdysone 3b-reductase; n=1; Tri... 89 1e-16
UniRef50_UPI00015B56A3 Cluster: PREDICTED: similar to aldo-keto ... 87 5e-16
UniRef50_UPI00015B56A2 Cluster: PREDICTED: similar to GA10458-PA... 83 1e-14
UniRef50_Q7PLK6 Cluster: CG40064-PA; n=1; Drosophila melanogaste... 79 2e-13
UniRef50_UPI0000588153 Cluster: PREDICTED: hypothetical protein;... 77 9e-13
UniRef50_Q8VC28 Cluster: Aldo-keto reductase family 1 member C13... 75 4e-12
UniRef50_Q54B70 Cluster: Aldehyde reductase; n=2; Dictyostelium ... 73 9e-12
UniRef50_Q0VGY1 Cluster: 3-alpha-hydroxysteroid dehydrogenase; n... 72 2e-11
UniRef50_A3U9Y0 Cluster: Aldehyde reductase; n=5; Bacteroidetes|... 72 3e-11
UniRef50_Q5BKE9 Cluster: LOC594893 protein; n=5; Xenopus tropica... 71 3e-11
UniRef50_Q8K023 Cluster: Aldo-keto reductase family 1 member C18... 69 2e-10
UniRef50_Q7ZWA4 Cluster: Zgc:56622; n=6; cellular organisms|Rep:... 68 3e-10
UniRef50_Q2LZ66 Cluster: GA19341-PA; n=2; Endopterygota|Rep: GA1... 68 3e-10
UniRef50_Q7QK25 Cluster: ENSANGP00000019775; n=2; Anopheles gamb... 68 4e-10
UniRef50_A2EHN6 Cluster: Oxidoreductase, aldo/keto reductase fam... 67 6e-10
UniRef50_Q7PCV3 Cluster: ENSANGP00000031808; n=9; Endopterygota|... 67 8e-10
UniRef50_Q9VTL0 Cluster: CG6083-PA; n=4; Diptera|Rep: CG6083-PA ... 66 1e-09
UniRef50_Q9NAI5 Cluster: Putative uncharacterized protein; n=3; ... 65 2e-09
UniRef50_Q6TY50 Cluster: Reductase 2; n=10; Magnoliophyta|Rep: R... 65 3e-09
UniRef50_Q5FT75 Cluster: Putative 2,5-diketo-D-gluconic acid red... 64 4e-09
UniRef50_Q7JVH6 Cluster: LD24696p; n=2; Sophophora|Rep: LD24696p... 64 4e-09
UniRef50_A2FPE2 Cluster: Oxidoreductase, aldo/keto reductase fam... 64 7e-09
UniRef50_P45376 Cluster: Aldose reductase; n=21; Bilateria|Rep: ... 63 9e-09
UniRef50_Q17DN0 Cluster: Aldo-keto reductase; n=5; Culicidae|Rep... 63 1e-08
UniRef50_P27800 Cluster: Aldehyde reductase 1; n=18; root|Rep: A... 62 2e-08
UniRef50_Q03TW0 Cluster: Aldo/keto reductase of diketogulonate r... 62 3e-08
UniRef50_Q23320 Cluster: Putative uncharacterized protein; n=4; ... 62 3e-08
UniRef50_A3C1Z7 Cluster: Putative uncharacterized protein; n=2; ... 61 4e-08
UniRef50_Q2S340 Cluster: Aldehyde reductase; n=10; Bacteria|Rep:... 61 5e-08
UniRef50_P14550 Cluster: Alcohol dehydrogenase [NADP+]; n=44; Bi... 61 5e-08
UniRef50_P26690 Cluster: NAD(P)H-dependent 6'-deoxychalcone synt... 61 5e-08
UniRef50_UPI0000498F1F Cluster: oxidoreductase, aldo/keto reduct... 60 7e-08
UniRef50_A7CUW0 Cluster: 2,5-didehydrogluconate reductase; n=6; ... 60 7e-08
UniRef50_Q9U2J5 Cluster: Putative uncharacterized protein; n=2; ... 60 7e-08
UniRef50_Q8SSK6 Cluster: ALDOSE REDUCTASE; n=1; Encephalitozoon ... 60 7e-08
UniRef50_Q41E86 Cluster: 2,5-didehydrogluconate reductase; n=2; ... 60 1e-07
UniRef50_Q16K66 Cluster: Aldo-keto reductase; n=2; Aedes aegypti... 60 1e-07
UniRef50_A5PDA8 Cluster: Putative oxidoreductase protein; n=1; E... 59 2e-07
UniRef50_Q2UGR1 Cluster: Aldo/keto reductase family proteins; n=... 59 2e-07
UniRef50_Q28P63 Cluster: Aldo/keto reductase; n=4; Rhodobacterac... 59 2e-07
UniRef50_A6W8E7 Cluster: 2,5-didehydrogluconate reductase; n=3; ... 59 2e-07
UniRef50_P15339 Cluster: 2,5-diketo-D-gluconic acid reductase B;... 59 2e-07
UniRef50_Q7N0E4 Cluster: 2,5-diketo-D-gluconic acid reductase A;... 58 3e-07
UniRef50_Q5K8C5 Cluster: Aldo-keto reductase, putative; n=1; Fil... 58 3e-07
UniRef50_A2R6Z3 Cluster: Catalytic activity: an alcohol + NADP(+... 58 3e-07
UniRef50_UPI000023D0F1 Cluster: hypothetical protein FG03517.1; ... 58 3e-07
UniRef50_Q83N50 Cluster: 2,5-diketo-D-gluconic acid reductase; n... 58 3e-07
UniRef50_Q5FK98 Cluster: Oxidoreductase; n=8; Lactobacillales|Re... 58 3e-07
UniRef50_P38715 Cluster: NADPH-dependent aldose reductase GRE3; ... 58 3e-07
UniRef50_P06632 Cluster: 2,5-diketo-D-gluconic acid reductase A;... 58 3e-07
UniRef50_Q96UH3 Cluster: Aldehyde reductase; n=13; Pezizomycotin... 58 5e-07
UniRef50_P15121 Cluster: Aldose reductase; n=72; Eumetazoa|Rep: ... 58 5e-07
UniRef50_P51857 Cluster: 3-oxo-5-beta-steroid 4-dehydrogenase (E... 57 6e-07
UniRef50_Q01J82 Cluster: OSIGBa0152K17.5 protein; n=28; Magnolio... 56 1e-06
UniRef50_A7P424 Cluster: Chromosome chr1 scaffold_5, whole genom... 56 1e-06
UniRef50_Q968S3 Cluster: Aldoketoreductase-like protein; n=1; Or... 56 2e-06
UniRef50_Q7QVQ9 Cluster: GLP_302_44328_45269; n=1; Giardia lambl... 56 2e-06
UniRef50_Q8CI22 Cluster: 2310005E10Rik protein; n=30; Tetrapoda|... 55 2e-06
UniRef50_Q927E1 Cluster: Lin2848 protein; n=13; Listeria|Rep: Li... 55 2e-06
UniRef50_Q41399 Cluster: Chalcone reductase; n=4; eudicotyledons... 55 2e-06
UniRef50_UPI00015B40FA Cluster: PREDICTED: similar to CG2767-PA;... 55 3e-06
UniRef50_Q88SL1 Cluster: Oxidoreductase; n=51; Lactobacillales|R... 55 3e-06
UniRef50_Q5FKI1 Cluster: Reductase-dehydrogenase; n=1; Lactobaci... 55 3e-06
UniRef50_Q8J0K1 Cluster: 4-dihydromethyltrisporate dehydrogenase... 55 3e-06
UniRef50_Q7G765 Cluster: Probable NAD(P)H-dependent oxidoreducta... 55 3e-06
UniRef50_P47137 Cluster: Probable oxidoreductase YJR096W; n=8; S... 54 4e-06
UniRef50_Q8ZI40 Cluster: 2,5-diketo-D-gluconic acid reductase A;... 54 4e-06
UniRef50_UPI0000D56CE5 Cluster: PREDICTED: similar to CG6084-PA,... 54 6e-06
UniRef50_Q1VRG6 Cluster: YvgN; n=1; Psychroflexus torquis ATCC 7... 54 6e-06
UniRef50_A1UEC5 Cluster: 2,5-didehydrogluconate reductase; n=20;... 54 6e-06
UniRef50_Q1U9L6 Cluster: 2,5-didehydrogluconate reductase; n=3; ... 54 7e-06
UniRef50_Q0IBY6 Cluster: Alcohol dehydrogenase; n=2; Chroococcal... 54 7e-06
UniRef50_A7CWF9 Cluster: Aldehyde reductase; n=2; Bacteria|Rep: ... 54 7e-06
UniRef50_Q17G72 Cluster: Aldo-keto reductase; n=9; Endopterygota... 54 7e-06
UniRef50_A7SIT3 Cluster: Predicted protein; n=1; Nematostella ve... 54 7e-06
UniRef50_Q96JD6 Cluster: Aldo-keto reductase family 1 member C-l... 54 7e-06
UniRef50_UPI0000E4A7CE Cluster: PREDICTED: similar to LOC553452 ... 53 1e-05
UniRef50_Q9HGY0 Cluster: Glycerol dehydrogenase; n=8; Saccharomy... 53 1e-05
UniRef50_Q8ZH36 Cluster: 2,5-diketo-D-gluconic acid reductase B;... 53 1e-05
UniRef50_UPI00015B4B22 Cluster: PREDICTED: similar to GA15457-PA... 52 2e-05
UniRef50_UPI00015B4912 Cluster: PREDICTED: similar to aldo-keto ... 52 2e-05
UniRef50_Q7WSY4 Cluster: Putative aldo-keto reductase; n=1; Prop... 52 2e-05
UniRef50_Q17DN1 Cluster: Aldo-keto reductase; n=1; Aedes aegypti... 52 2e-05
UniRef50_Q9P6D3 Cluster: Related to aldo-keto reductase YPR1; n=... 52 2e-05
UniRef50_Q4PDR0 Cluster: Putative uncharacterized protein; n=1; ... 52 2e-05
UniRef50_A5E082 Cluster: GCY protein; n=4; Saccharomycetales|Rep... 52 2e-05
UniRef50_A7BA05 Cluster: Putative uncharacterized protein; n=1; ... 52 2e-05
UniRef50_Q55FL3 Cluster: Aldo-keto reductase; n=2; Dictyostelium... 52 2e-05
UniRef50_P14065 Cluster: Protein GCY; n=13; Saccharomycetales|Re... 52 2e-05
UniRef50_UPI000065D0BD Cluster: Homolog of Homo sapiens "AKR1B1 ... 52 3e-05
UniRef50_Q96JD6-2 Cluster: Isoform 2 of Q96JD6 ; n=4; Catarrhini... 52 3e-05
UniRef50_A5VK30 Cluster: 2,5-didehydrogluconate reductase; n=2; ... 52 3e-05
UniRef50_Q05KR9 Cluster: Benzil reductase; n=5; Bacillales|Rep: ... 51 4e-05
UniRef50_A3JU52 Cluster: 2,5-diketo-D-gluconic acid reductase A;... 51 4e-05
UniRef50_Q6CEJ0 Cluster: Yarrowia lipolytica chromosome B of str... 51 4e-05
UniRef50_Q7G764 Cluster: Probable NAD(P)H-dependent oxidoreducta... 51 4e-05
UniRef50_Q9FJK0 Cluster: Aldose reductase-like protein; n=3; cor... 51 5e-05
UniRef50_Q5KI95 Cluster: Aldo-keto reductase, putative; n=14; Di... 51 5e-05
UniRef50_Q4PAT5 Cluster: Putative uncharacterized protein; n=1; ... 51 5e-05
UniRef50_Q890A0 Cluster: Oxidoreductase; n=6; Lactobacillales|Re... 50 7e-05
UniRef50_Q5FK99 Cluster: Oxidoreductase aldo-keto reductase fami... 50 7e-05
UniRef50_Q24C22 Cluster: Oxidoreductase, aldo/keto reductase fam... 50 7e-05
UniRef50_UPI000155CAC7 Cluster: PREDICTED: hypothetical protein;... 50 9e-05
UniRef50_Q0SFM4 Cluster: Probable 2,5-didehydrogluconate reducta... 50 9e-05
UniRef50_A2UAH0 Cluster: Aldo/keto reductase; n=1; Bacillus coag... 50 9e-05
UniRef50_A0JRJ3 Cluster: 2,5-didehydrogluconate reductase; n=3; ... 50 9e-05
UniRef50_A2EYY6 Cluster: Oxidoreductase, aldo/keto reductase fam... 50 9e-05
UniRef50_UPI0000E45E29 Cluster: PREDICTED: similar to aldose red... 50 1e-04
UniRef50_Q4JX70 Cluster: Putative oxidoreductase; n=1; Corynebac... 50 1e-04
UniRef50_A6RKL9 Cluster: Putative uncharacterized protein; n=3; ... 50 1e-04
UniRef50_A2QBD7 Cluster: Catalytic activity: an alcohol + NADP(+... 50 1e-04
UniRef50_A1D4E3 Cluster: D-xylose reductase (Xyl1), putative; n=... 50 1e-04
UniRef50_Q6F7K7 Cluster: 2,5-diketo-D-gluconate reductase; n=20;... 49 2e-04
UniRef50_Q1YPE5 Cluster: Aldehyde reductase; n=7; Bacteria|Rep: ... 49 2e-04
UniRef50_Q9USV2 Cluster: Xylose and arabinose reductase; n=2; Sc... 49 2e-04
UniRef50_P22045 Cluster: Probable reductase; n=101; cellular org... 49 2e-04
UniRef50_Q8F1G4 Cluster: Aldehyde reductase; n=8; Bacteria|Rep: ... 49 2e-04
UniRef50_Q8ET73 Cluster: 2,5-diketo-D-gluconate reductase; n=12;... 49 2e-04
UniRef50_Q2V420 Cluster: Uncharacterized protein At2g37770.1; n=... 49 2e-04
UniRef50_Q0PGJ6 Cluster: Aldo-keto reductase; n=32; Magnoliophyt... 49 2e-04
UniRef50_A3LWP0 Cluster: Aldo/keto reductase; n=7; Saccharomycet... 49 2e-04
UniRef50_A3LTU8 Cluster: D-arabinose dehydrogenase; n=5; Sacchar... 49 2e-04
UniRef50_Q10494 Cluster: Probable oxidoreductase C26F1.07; n=2; ... 49 2e-04
UniRef50_A2RMU6 Cluster: Oxidoreductase, aldo/keto reductase fam... 48 3e-04
UniRef50_A0JX62 Cluster: 2,5-didehydrogluconate reductase; n=9; ... 48 3e-04
UniRef50_Q4P1G1 Cluster: Putative uncharacterized protein; n=1; ... 48 3e-04
UniRef50_Q89JN4 Cluster: Oxidoreductase; n=8; Rhizobiales|Rep: O... 48 4e-04
UniRef50_Q6NII7 Cluster: Putative oxidoreductase; n=2; Corynebac... 48 4e-04
UniRef50_Q03PG5 Cluster: Aldo/keto reductase of diketogulonate r... 48 4e-04
UniRef50_Q7ZA52 Cluster: Aldose reductase; n=6; Pezizomycotina|R... 48 4e-04
UniRef50_Q6RZX1 Cluster: Gld1; n=22; Pezizomycotina|Rep: Gld1 - ... 48 4e-04
UniRef50_Q5B034 Cluster: Putative uncharacterized protein; n=1; ... 48 4e-04
UniRef50_Q5T2L2 Cluster: Aldo-keto reductase family 1 member C-l... 48 4e-04
UniRef50_A5KSS3 Cluster: Aldehyde reductase; n=1; candidate divi... 48 5e-04
UniRef50_Q572D2 Cluster: Aldo-keto reductase, putative; n=1; Phy... 48 5e-04
UniRef50_Q22352 Cluster: Putative uncharacterized protein T08H10... 48 5e-04
UniRef50_Q6CFG7 Cluster: Yarrowia lipolytica chromosome B of str... 48 5e-04
UniRef50_P23901 Cluster: Aldose reductase; n=9; Poaceae|Rep: Ald... 48 5e-04
UniRef50_UPI0000519CC2 Cluster: PREDICTED: similar to CG2767-PA;... 47 7e-04
UniRef50_Q9ZBW7 Cluster: Putative oxidoreductase; n=2; Actinomyc... 47 7e-04
UniRef50_Q03XK0 Cluster: Aldo/keto reductase of diketogulonate r... 47 7e-04
UniRef50_A0AWM8 Cluster: Aldo/keto reductase; n=4; Actinomycetal... 47 7e-04
UniRef50_Q7VG53 Cluster: Aldo-keto reductase; n=28; Bacteria|Rep... 47 9e-04
UniRef50_Q14LU6 Cluster: Putative aldo/keto reductase oxidoreduc... 47 9e-04
UniRef50_Q9VHX4 Cluster: CG2767-PA; n=4; Endopterygota|Rep: CG27... 47 9e-04
UniRef50_Q3E9M9 Cluster: Uncharacterized protein At5g01670.2; n=... 46 0.001
UniRef50_Q4Q5N9 Cluster: Prostaglandin f synthase, putative; n=7... 46 0.001
UniRef50_Q235V6 Cluster: Oxidoreductase, aldo/keto reductase fam... 46 0.001
UniRef50_A7SGW6 Cluster: Predicted protein; n=1; Nematostella ve... 46 0.001
UniRef50_Q4P4P1 Cluster: Putative uncharacterized protein; n=1; ... 46 0.001
UniRef50_A2QVE5 Cluster: Similarity: shows similarity to several... 46 0.001
UniRef50_Q9X0A2 Cluster: Oxidoreductase, aldo/keto reductase fam... 46 0.002
UniRef50_Q1IN88 Cluster: Aldehyde reductase; n=5; Bacteria|Rep: ... 46 0.002
UniRef50_Q7XY49 Cluster: Mannose 6-phosphate reductase; n=1; Gri... 46 0.002
UniRef50_Q0CK00 Cluster: Predicted protein; n=1; Aspergillus ter... 46 0.002
UniRef50_P28475 Cluster: NADP-dependent D-sorbitol-6-phosphate d... 46 0.002
UniRef50_Q568D7 Cluster: Zgc:110366; n=7; Euteleostomi|Rep: Zgc:... 46 0.002
UniRef50_A5DRJ6 Cluster: Putative uncharacterized protein; n=4; ... 46 0.002
UniRef50_Q88TV9 Cluster: Oxidoreductase; n=4; Lactobacillus|Rep:... 45 0.003
UniRef50_Q1RFP0 Cluster: 2,5-diketo-D-gluconic acid reductase A;... 45 0.003
UniRef50_A6ESC0 Cluster: ARA1; n=1; unidentified eubacterium SCB... 45 0.003
UniRef50_Q01HB5 Cluster: OSIGBa0136O08-OSIGBa0153H12.9 protein; ... 45 0.003
UniRef50_Q76L37 Cluster: Conjugated polyketone reductase C1; n=3... 45 0.003
UniRef50_Q4WP69 Cluster: Aldehyde reductase, putative; n=1; Aspe... 45 0.003
UniRef50_Q043M4 Cluster: Aldo/keto reductase of diketogulonate r... 45 0.003
UniRef50_Q03U37 Cluster: Aldo/keto reductase of diketogulonate r... 45 0.003
UniRef50_A3VRL4 Cluster: Putative uncharacterized protein; n=1; ... 45 0.003
UniRef50_Q68ST9 Cluster: Reductase AKOR2; n=2; Pleurotus djamor|... 45 0.003
UniRef50_P38115 Cluster: D-arabinose dehydrogenase [NAD(P)+] hea... 45 0.003
UniRef50_Q927P9 Cluster: Lin2739 protein; n=12; Bacteria|Rep: Li... 44 0.005
UniRef50_Q8EUH6 Cluster: Oxidoreductase; n=1; Mycoplasma penetra... 44 0.005
UniRef50_Q4V008 Cluster: Oxidoreductase; n=4; Proteobacteria|Rep... 44 0.005
UniRef50_P70883 Cluster: AkrI; n=1; Butyrivibrio fibrisolvens|Re... 44 0.005
UniRef50_A4RQH8 Cluster: Predicted protein; n=2; Ostreococcus|Re... 44 0.005
UniRef50_Q5TNP1 Cluster: ENSANGP00000029046; n=2; Culicidae|Rep:... 44 0.005
UniRef50_Q6C2L0 Cluster: Yarrowia lipolytica chromosome F of str... 44 0.005
UniRef50_A2QL02 Cluster: Putative frameshift; n=1; Aspergillus n... 44 0.005
UniRef50_UPI00006CCCD7 Cluster: oxidoreductase, aldo/keto reduct... 44 0.006
UniRef50_Q5BLA6 Cluster: Zgc:110782; n=2; Danio rerio|Rep: Zgc:1... 44 0.006
UniRef50_Q11B35 Cluster: Aldo/keto reductase; n=1; Mesorhizobium... 44 0.006
UniRef50_A4FEB9 Cluster: 2,5-diketo-D-gluconic acid reductase; n... 44 0.006
UniRef50_Q9ZUJ6 Cluster: T2K10.1 protein; n=16; core eudicotyled... 44 0.006
UniRef50_Q75E75 Cluster: ABL209Cp; n=1; Eremothecium gossypii|Re... 44 0.006
UniRef50_A2QB88 Cluster: Contig An01c0460, complete genome. prec... 44 0.006
UniRef50_A4IJ00 Cluster: LOC548351 protein; n=1; Xenopus tropica... 44 0.008
UniRef50_Q5B5R6 Cluster: Putative uncharacterized protein; n=1; ... 44 0.008
UniRef50_Q0CLQ2 Cluster: Putative uncharacterized protein; n=1; ... 44 0.008
UniRef50_Q8Y463 Cluster: Lmo2592 protein; n=40; Bacteria|Rep: Lm... 43 0.011
UniRef50_A6LZ55 Cluster: 2,5-didehydrogluconate reductase; n=1; ... 43 0.011
UniRef50_A5AD50 Cluster: Putative uncharacterized protein; n=3; ... 43 0.011
UniRef50_Q1DLF1 Cluster: Putative uncharacterized protein; n=1; ... 43 0.011
UniRef50_Q838E0 Cluster: Oxidoreductase, aldo/keto reductase fam... 43 0.014
UniRef50_Q7PM68 Cluster: ENSANGP00000014386; n=1; Anopheles gamb... 43 0.014
UniRef50_Q76L36 Cluster: Conjugated polyketone reductase C2; n=1... 43 0.014
UniRef50_UPI00006CD296 Cluster: oxidoreductase, aldo/keto reduct... 42 0.018
UniRef50_Q929C8 Cluster: Lin2349 protein; n=12; Listeria|Rep: Li... 42 0.018
UniRef50_Q5FLI5 Cluster: Aldehyde reductase; n=2; Bacteria|Rep: ... 42 0.018
UniRef50_Q1Q8W8 Cluster: Aldo/keto reductase; n=1; Psychrobacter... 42 0.018
UniRef50_Q4WI64 Cluster: Aldehyde reductase, putative; n=22; Pez... 42 0.018
UniRef50_A6SI80 Cluster: Putative uncharacterized protein; n=1; ... 42 0.018
UniRef50_A6RMS0 Cluster: Putative uncharacterized protein; n=1; ... 42 0.018
UniRef50_P82125 Cluster: 1,5-anhydro-D-fructose reductase; n=1; ... 42 0.018
UniRef50_A7RRF6 Cluster: Predicted protein; n=2; Nematostella ve... 42 0.024
UniRef50_UPI00015B5BD7 Cluster: PREDICTED: similar to aldo-keto ... 42 0.032
UniRef50_UPI0000D9A956 Cluster: PREDICTED: similar to aldo-keto ... 42 0.032
UniRef50_Q6U5V3 Cluster: Putative uncharacterized protein; n=1; ... 42 0.032
UniRef50_A5BYJ4 Cluster: Putative uncharacterized protein; n=1; ... 42 0.032
UniRef50_Q4WUF7 Cluster: Aldo-keto reductase, putative; n=3; Pez... 42 0.032
UniRef50_Q4WF80 Cluster: Glycerol dehydrogenase (GCY1), putative... 42 0.032
UniRef50_A6VNW9 Cluster: Aldo/keto reductase precursor; n=1; Act... 41 0.043
UniRef50_A0L1A2 Cluster: Aldo/keto reductase; n=8; Gammaproteoba... 41 0.043
UniRef50_Q5KKZ8 Cluster: Aldo-keto reductase, putative; n=2; Fil... 41 0.043
UniRef50_Q5HR31 Cluster: Oxidoreductase, aldo/keto reductase fam... 41 0.056
UniRef50_A7PNI3 Cluster: Chromosome chr1 scaffold_22, whole geno... 41 0.056
UniRef50_O13848 Cluster: NADH/NADPH dependent indole-3-acetaldeh... 41 0.056
UniRef50_A7RUA2 Cluster: Predicted protein; n=1; Nematostella ve... 40 0.075
UniRef50_Q2U219 Cluster: Aldo/keto reductase family proteins; n=... 40 0.075
UniRef50_A7ALH6 Cluster: Putative uncharacterized protein; n=1; ... 40 0.099
UniRef50_A5BF24 Cluster: Putative uncharacterized protein; n=1; ... 40 0.099
UniRef50_Q4FY75 Cluster: Aldo-keto reductase-like protein; n=5; ... 40 0.099
UniRef50_A7D6Q0 Cluster: Aldo/keto reductase; n=1; Halorubrum la... 40 0.099
UniRef50_Q07551 Cluster: NADPH-dependent alpha-keto amide reduct... 40 0.099
UniRef50_UPI0000499B0E Cluster: oxidoreductase, aldo/keto reduct... 40 0.13
UniRef50_Q1M4Z6 Cluster: Putative aldo-keto reductase/oxidase; n... 40 0.13
UniRef50_Q2H7A8 Cluster: Putative uncharacterized protein; n=1; ... 40 0.13
UniRef50_Q8EVT8 Cluster: Oxidoreductase-aldo/keto reductase fami... 39 0.17
UniRef50_A7BES9 Cluster: Putative uncharacterized protein; n=1; ... 39 0.17
UniRef50_A6WDZ5 Cluster: Aldo/keto reductase; n=5; Bacteria|Rep:... 39 0.17
UniRef50_Q5V398 Cluster: Oxidoreductase aldo/keto reductase fami... 39 0.17
UniRef50_Q11BF8 Cluster: Aldo/keto reductase; n=12; Bacteria|Rep... 39 0.23
UniRef50_A3VHZ9 Cluster: Oxidoreductase; n=1; Rhodobacterales ba... 39 0.23
UniRef50_A0JRJ6 Cluster: Aldo/keto reductase; n=2; Micrococcinea... 39 0.23
UniRef50_P91021 Cluster: Putative uncharacterized protein; n=1; ... 39 0.23
UniRef50_Q979I4 Cluster: Aldo / keto reductase; n=3; Archaea|Rep... 39 0.23
UniRef50_Q8G7K9 Cluster: Dehydrogenase or reductase protein; n=4... 38 0.30
UniRef50_Q1PV10 Cluster: Putative uncharacterized protein; n=1; ... 38 0.30
UniRef50_A1RB46 Cluster: 2,5-diketo-D-gluconate reductase; n=1; ... 38 0.30
UniRef50_Q5UX52 Cluster: Oxidoreductase aldo/keto reductase fami... 38 0.30
UniRef50_UPI0000DB6EE9 Cluster: PREDICTED: similar to C35D10.6; ... 38 0.40
UniRef50_Q7NB44 Cluster: ARA1; n=3; Firmicutes|Rep: ARA1 - Mycop... 38 0.40
UniRef50_Q2CAL9 Cluster: 2,5-didehydrogluconate reductase; n=2; ... 38 0.40
UniRef50_Q03X85 Cluster: Aldo/keto reductase of diketogulonate r... 38 0.40
UniRef50_A6PR52 Cluster: Aldo/keto reductase; n=1; Victivallis v... 38 0.40
UniRef50_A3UJS6 Cluster: Oxidoreductase; n=3; Alphaproteobacteri... 38 0.40
UniRef50_Q9A2X8 Cluster: Oxidoreductase, aldo/keto reductase fam... 38 0.53
UniRef50_Q5NLW3 Cluster: Putative oxidoreductase; n=1; Zymomonas... 38 0.53
UniRef50_Q5KCN9 Cluster: Putative uncharacterized protein; n=1; ... 38 0.53
UniRef50_UPI00005A2CCB Cluster: PREDICTED: similar to Aldose red... 37 0.70
UniRef50_Q7R2T6 Cluster: GLP_291_56367_57278; n=1; Giardia lambl... 37 0.70
UniRef50_Q9C1X5 Cluster: Xylose and arabinose reductase; n=1; Sc... 37 0.70
UniRef50_Q9HM42 Cluster: Alcohol dehydrogenase related protein; ... 37 0.70
UniRef50_Q9QWA5 Cluster: Aldose reductase; n=5; Euarchontoglires... 37 0.92
UniRef50_Q9X265 Cluster: Oxidoreductase, aldo/keto reductase fam... 37 0.92
UniRef50_A7RPK2 Cluster: Predicted protein; n=1; Nematostella ve... 37 0.92
UniRef50_Q8EVS8 Cluster: Oxidoreductase; n=1; Mycoplasma penetra... 36 1.2
UniRef50_Q8DK16 Cluster: Tlr1054 protein; n=6; Cyanobacteria|Rep... 36 1.2
UniRef50_A6NPD6 Cluster: Putative uncharacterized protein; n=3; ... 36 1.2
UniRef50_A4YQ04 Cluster: 2,5-diketo-D-gluconate reductase B; n=1... 36 1.2
UniRef50_Q00XM4 Cluster: Aldo/keto reductase family proteins; n=... 36 1.2
UniRef50_Q55FL2 Cluster: Putative uncharacterized protein; n=1; ... 36 1.2
UniRef50_Q21274 Cluster: Putative uncharacterized protein; n=1; ... 36 1.2
UniRef50_Q7M4N1 Cluster: Dihydrodiol dehydrogenase DD2; n=2; Hom... 36 1.2
UniRef50_Q9P734 Cluster: Related to 2, 5-diketo-D-gluconic acid ... 36 1.2
UniRef50_Q4PE96 Cluster: Putative uncharacterized protein; n=1; ... 36 1.2
UniRef50_O14088 Cluster: Xylose and arabinose reductase; n=1; Sc... 36 1.2
UniRef50_A7TLC4 Cluster: Putative uncharacterized protein; n=1; ... 36 1.2
UniRef50_Q5V663 Cluster: Aldehyde reductase; n=6; Halobacteriace... 36 1.2
UniRef50_UPI00006CA3CB Cluster: oxidoreductase, aldo/keto reduct... 36 1.6
UniRef50_Q3CZS2 Cluster: Oxidoreductase, aldo/keto reductase fam... 36 1.6
UniRef50_Q2BBN7 Cluster: YvgN; n=1; Bacillus sp. NRRL B-14911|Re... 36 1.6
UniRef50_Q11DV1 Cluster: Aldo/keto reductase; n=10; Alphaproteob... 36 1.6
UniRef50_A3WP89 Cluster: Aldo/keto reductase; n=1; Idiomarina ba... 36 1.6
UniRef50_A3T261 Cluster: Putative uncharacterized protein; n=1; ... 36 1.6
UniRef50_Q9ZUX0 Cluster: Expressed protein; n=11; cellular organ... 36 1.6
UniRef50_Q54NR2 Cluster: Aldo-keto reductase; n=3; Dictyostelium... 36 1.6
UniRef50_Q59Z55 Cluster: Potential aldo/keto reductase; n=6; Sac... 36 1.6
UniRef50_Q0TYC7 Cluster: Predicted protein; n=1; Phaeosphaeria n... 36 1.6
UniRef50_Q15NA5 Cluster: Aldo/keto reductase; n=2; Gammaproteoba... 36 2.1
UniRef50_Q03BE0 Cluster: Aldo/keto reductase family enzyme; n=5;... 36 2.1
UniRef50_A5ZYE6 Cluster: Putative uncharacterized protein; n=1; ... 36 2.1
UniRef50_A6R5B4 Cluster: NAD(P)H-dependent D-xylose reductase; n... 36 2.1
UniRef50_A1CAM7 Cluster: Aldo-keto reductase, putative; n=9; Dik... 36 2.1
UniRef50_Q5KKC5 Cluster: Putative uncharacterized protein; n=2; ... 35 2.8
UniRef50_Q2H1Q3 Cluster: Putative uncharacterized protein; n=1; ... 35 2.8
UniRef50_Q6L139 Cluster: 2,5-diketo-D-gluconic acid reductase; n... 35 2.8
UniRef50_Q02198 Cluster: Morphine 6-dehydrogenase; n=5; Bacteria... 35 2.8
UniRef50_Q5XJM7 Cluster: Zgc:101765; n=5; Eumetazoa|Rep: Zgc:101... 35 3.7
UniRef50_Q5KPU6 Cluster: Putative uncharacterized protein; n=2; ... 35 3.7
UniRef50_Q7UN76 Cluster: Putative uncharacterized protein; n=1; ... 34 4.9
UniRef50_Q14LA8 Cluster: Putative aldo/keto reductase oxidoreduc... 34 4.9
UniRef50_Q6CWB9 Cluster: Similarities with sp|Q12458 Saccharomyc... 34 4.9
UniRef50_A6QVW8 Cluster: Predicted protein; n=1; Ajellomyces cap... 34 4.9
UniRef50_A0LJ47 Cluster: Aldo/keto reductase; n=1; Syntrophobact... 34 6.5
UniRef50_Q4U2V7 Cluster: Hydroxyproline-rich glycoprotein GAS31 ... 34 6.5
UniRef50_A7PNT1 Cluster: Chromosome chr8 scaffold_23, whole geno... 34 6.5
UniRef50_Q18483 Cluster: Putative uncharacterized protein; n=2; ... 34 6.5
UniRef50_Q59ZT1 Cluster: Putative uncharacterized protein; n=1; ... 34 6.5
UniRef50_Q97U17 Cluster: Oxidoreductase, aldo/keto reductase fam... 34 6.5
UniRef50_Q4JCC1 Cluster: 2,5-diketo-D-gluconic acid reductase A;... 34 6.5
UniRef50_P55804 Cluster: NADP(+)-dependent glycerol dehydrogenas... 34 6.5
UniRef50_UPI0000F30DFE Cluster: UPI0000F30DFE related cluster; n... 33 8.6
UniRef50_Q2FAU0 Cluster: Rh31; n=2; Cercopithecine herpesvirus 8... 33 8.6
UniRef50_A5FMX5 Cluster: Putative uncharacterized protein precur... 33 8.6
UniRef50_Q18903 Cluster: Putative uncharacterized protein C56G3.... 33 8.6
UniRef50_Q4PHK0 Cluster: Putative uncharacterized protein; n=1; ... 33 8.6
UniRef50_A6RYK4 Cluster: Putative uncharacterized protein; n=1; ... 33 8.6
UniRef50_A1CLD1 Cluster: Gamma-cysteine synthetase regulatory su... 33 8.6
>UniRef50_Q9Y020 Cluster: 3-dehydroecdysone 3beta-reductase
precursor; n=1; Spodoptera littoralis|Rep:
3-dehydroecdysone 3beta-reductase precursor - Spodoptera
littoralis (Egyptian cotton leafworm)
Length = 345
Score = 93.1 bits (221), Expect = 1e-17
Identities = 50/113 (44%), Positives = 72/113 (63%), Gaps = 1/113 (0%)
Frame = +3
Query: 345 KFSEG-LKRESIFITTKLWNSYHEREQVIPALRKSLXKSQLGIRRPVFDSLAHSYV*ERY 521
K EG +KRE +F+TTKLWN++H+REQV A++++L K+ L +F + E Y
Sbjct: 91 KIDEGVIKREDVFLTTKLWNTHHKREQVAVAMKETLNKTGLDYV-DLFLMHWPIALNEDY 149
Query: 522 LARHVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGLEKPSALQIE 680
+ D+L+TWR + KLG TKSIG+SNFN+ Q+ ++ KP ALQIE
Sbjct: 150 SHSNTDYLETWRATEEMVKLGYTKSIGLSNFNKLQVATVLQECTIKPVALQIE 202
Score = 60.9 bits (141), Expect = 5e-08
Identities = 31/89 (34%), Positives = 46/89 (51%)
Frame = +2
Query: 83 AGFLFCLSALCFTSADLIVPTLQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIY 262
A F+ L+ SA + VP L++ + +P +ALGT+LG G V V+
Sbjct: 4 ASFILLLACCGAMSATIDVPMLKMLNDREMPAIALGTYLGFDKGGAVTSKDKQLRNVVMQ 63
Query: 263 ALEAGYTHIDTAYKYGIEDQVGRALXQEI 349
A++ GY H DTA Y E +VG A+ +I
Sbjct: 64 AIDLGYRHFDTAAIYNTEAEVGEAIRMKI 92
>UniRef50_Q8WRT0 Cluster: 3-dehydrecdysone 3b-reductase; n=1;
Trichoplusia ni|Rep: 3-dehydrecdysone 3b-reductase -
Trichoplusia ni (Cabbage looper)
Length = 308
Score = 89.4 bits (212), Expect = 1e-16
Identities = 53/109 (48%), Positives = 67/109 (61%), Gaps = 2/109 (1%)
Frame = +3
Query: 360 LKRESIFITTKLWNSYHEREQVIPALRKSLXKSQLGIRRPVFDSLAHS--YV*ERYLARH 533
+KRE +F+TTKLWN H R QV+PALR+SL K LG+ V L HS E
Sbjct: 91 VKREELFVTTKLWNDKHGRHQVVPALRESLTK--LGLSY-VDLYLIHSPEATNENGDPVD 147
Query: 534 VDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGLEKPSALQIE 680
+D L+TW GM +AKKLGL KSIG+SNF+ + R+I P+ QIE
Sbjct: 148 IDVLNTWNGMEEAKKLGLAKSIGVSNFDTALLDRLIAGSNTVPAVNQIE 196
Score = 55.2 bits (127), Expect = 2e-06
Identities = 34/82 (41%), Positives = 47/82 (57%), Gaps = 1/82 (1%)
Frame = +2
Query: 140 PTLQLSSGGNIPVVALGTW-LGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIE 316
P QL+ G IP +ALGT+ G PK QAV++A++AGY HIDTA YG E
Sbjct: 25 PLKQLNDGNAIPSLALGTFGFGDIPK---------VRQAVLWAIQAGYRHIDTAALYGNE 75
Query: 317 DQVGRALXQEILRRT*KRIYLY 382
++VG+ + I + KR L+
Sbjct: 76 EEVGKGIADAIQQGLVKREELF 97
>UniRef50_UPI00015B56A3 Cluster: PREDICTED: similar to aldo-keto
reductase; n=1; Nasonia vitripennis|Rep: PREDICTED:
similar to aldo-keto reductase - Nasonia vitripennis
Length = 321
Score = 87.4 bits (207), Expect = 5e-16
Identities = 50/124 (40%), Positives = 75/124 (60%), Gaps = 11/124 (8%)
Frame = +3
Query: 342 KKFSEGL-KRESIFITTKLWNSYHEREQVIPALRKSLXKSQLG------IRRPVFDSLAH 500
+K +G+ KRE +F+ TK+WN ++E V+ A ++SL K LG + P + +
Sbjct: 66 EKIDQGVVKREDLFVVTKVWNDERKQELVVAACKRSLKKLGLGYIDLYLVHWPFSYPILY 125
Query: 501 SY-V*ERYLA---RHVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGLEKPSA 668
Y V Y A VD+++TWRGM + KLGLT+SIG+SNFN +Q+ R+++S KP
Sbjct: 126 QYIVLPTYNAVTLDEVDYIETWRGMEECIKLGLTRSIGVSNFNSQQLTRLLESASIKPVM 185
Query: 669 LQIE 680
QIE
Sbjct: 186 NQIE 189
Score = 54.0 bits (124), Expect = 6e-06
Identities = 31/82 (37%), Positives = 45/82 (54%)
Frame = +2
Query: 137 VPTLQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIE 316
V + LS G +PV+ LGTW G +V E AV A++AGY H D A YG E
Sbjct: 5 VDEITLSDGNKVPVLGLGTWQGGNDPDEV-------ENAVKLAIDAGYRHFDCASFYGNE 57
Query: 317 DQVGRALXQEILRRT*KRIYLY 382
++G+A+ ++I + KR L+
Sbjct: 58 AEIGKAIQEKIDQGVVKREDLF 79
>UniRef50_UPI00015B56A2 Cluster: PREDICTED: similar to GA10458-PA;
n=2; Nasonia vitripennis|Rep: PREDICTED: similar to
GA10458-PA - Nasonia vitripennis
Length = 569
Score = 82.6 bits (195), Expect = 1e-14
Identities = 47/124 (37%), Positives = 71/124 (57%), Gaps = 11/124 (8%)
Frame = +3
Query: 342 KKFSEG-LKRESIFITTKLWNSYHEREQVIPALRKSLXKSQLG------IRRPVF----D 488
+K ++G +KRE IF+TTKLW + H+ ++V+PA +KSL + P D
Sbjct: 62 EKINDGTIKREDIFVTTKLWCNSHKEDEVVPACKKSLENLGFDYIDLFLVHWPFAFKSGD 121
Query: 489 SLAHSYV*ERYLARHVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGLEKPSA 668
+L + D+L+TW+GM + K+ GL +SIG+SNFN EQI R++ S KP
Sbjct: 122 ALTPRDAAGKIEFSDTDYLETWKGMEECKRQGLARSIGLSNFNSEQIARLLSSAKIKPVN 181
Query: 669 LQIE 680
Q+E
Sbjct: 182 NQVE 185
Score = 79.4 bits (187), Expect = 1e-13
Identities = 45/121 (37%), Positives = 70/121 (57%), Gaps = 8/121 (6%)
Frame = +3
Query: 342 KKFSEG-LKRESIFITTKLWNSYHEREQVIPALRKSLXKSQLG------IRRPVFDSLAH 500
+K +G +KRE +F+TTKL H+ +V+PA ++SL L I P+ H
Sbjct: 322 EKIKDGTVKREDLFVTTKLSYYAHKESEVVPACKQSLNDLGLDYIDLYLIHWPIRRYFRH 381
Query: 501 SY-V*ERYLARHVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGLEKPSALQI 677
+ + L D+L+TW+GM + K+ GL +SIG+SNFN EQI R++++ KP Q+
Sbjct: 382 NKNASGKLLLSDTDYLETWKGMEECKRQGLARSIGVSNFNSEQITRLLEAAKIKPVNNQV 441
Query: 678 E 680
E
Sbjct: 442 E 442
Score = 53.2 bits (122), Expect = 1e-05
Identities = 31/78 (39%), Positives = 48/78 (61%)
Frame = +2
Query: 137 VPTLQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIE 316
VPT+ + G +P++ LGT+L +P G+V + AV YA+E GY H+DTA+ Y E
Sbjct: 3 VPTVTFNDGYKMPMIGLGTFLS-KP-GEVAE-------AVKYAIEVGYRHVDTAFFYENE 53
Query: 317 DQVGRALXQEILRRT*KR 370
++G A+ ++I T KR
Sbjct: 54 KEIGSAIREKINDGTIKR 71
>UniRef50_Q7PLK6 Cluster: CG40064-PA; n=1; Drosophila
melanogaster|Rep: CG40064-PA - Drosophila melanogaster
(Fruit fly)
Length = 361
Score = 78.6 bits (185), Expect = 2e-13
Identities = 47/119 (39%), Positives = 65/119 (54%), Gaps = 12/119 (10%)
Frame = +3
Query: 360 LKRESIFITTKLWNSYHEREQVIPALRKSLXK---SQLGIRRPVFDSLAHSYV*ERYLAR 530
+ RE+IF+TTKLWN++H+ V K L S + + F + + YV + L
Sbjct: 86 ISRENIFLTTKLWNTHHDPRDVRRICEKQLELLGFSYIDLYLMHFP-VGYKYVCDEILMP 144
Query: 531 ---------HVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGLEKPSALQIE 680
+D+LDTWR M + KLG+ +SIG+SNFN EQIQRII KP Q+E
Sbjct: 145 MSGDELQTVEIDYLDTWRAMENLVKLGMVRSIGLSNFNMEQIQRIIQCSSSKPVVNQVE 203
Score = 35.9 bits (79), Expect = 1.6
Identities = 16/33 (48%), Positives = 21/33 (63%)
Frame = +2
Query: 251 AVIYALEAGYTHIDTAYKYGIEDQVGRALXQEI 349
AV A+E G+ H DTAY Y E ++G AL +I
Sbjct: 49 AVHCAIETGFRHFDTAYYYENEKEIGEALRTQI 81
>UniRef50_UPI0000588153 Cluster: PREDICTED: hypothetical protein;
n=1; Strongylocentrotus purpuratus|Rep: PREDICTED:
hypothetical protein - Strongylocentrotus purpuratus
Length = 333
Score = 76.6 bits (180), Expect = 9e-13
Identities = 44/120 (36%), Positives = 65/120 (54%), Gaps = 12/120 (10%)
Frame = +3
Query: 357 GLKRESIFITTKLWNSYHEREQVIPALRKSLXKSQLG------IRRPV-FDSLAHSYV*E 515
GLKRE +FITTK+WN++H +E V +SL QL + P+ F +L + +
Sbjct: 67 GLKREDVFITTKVWNTFHAKEDVAECFNRSLTDLQLDYIDLYIMHWPLGFQNLGPTVMFP 126
Query: 516 R-----YLARHVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGLEKPSALQIE 680
R + V +L+TW M D K G KS+G+SNFN +Q+ ++ PS LQ+E
Sbjct: 127 RTETGDIVYSDVHYLETWSAMEDLVKTGKCKSLGLSNFNSKQLDDVLQHSTVPPSVLQVE 186
Score = 42.7 bits (96), Expect = 0.014
Identities = 30/76 (39%), Positives = 41/76 (53%)
Frame = +2
Query: 143 TLQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQ 322
++ L SG +P+V LGTW K K +V A+ A++AGY H D A YG E +
Sbjct: 4 SVTLPSGHAMPLVGLGTW-----KLKADEVAG----AIGAAVDAGYRHFDCALIYGNEKE 54
Query: 323 VGRALXQEILRRT*KR 370
VG AL + + R KR
Sbjct: 55 VGVALREAMQRLGLKR 70
>UniRef50_Q8VC28 Cluster: Aldo-keto reductase family 1 member C13;
n=11; Theria|Rep: Aldo-keto reductase family 1 member
C13 - Mus musculus (Mouse)
Length = 323
Score = 74.5 bits (175), Expect = 4e-12
Identities = 53/119 (44%), Positives = 69/119 (57%), Gaps = 12/119 (10%)
Frame = +3
Query: 360 LKRESIFITTKLWNSYHEREQVIPALRKSLXKSQLG------IRRPV-FDSLAHSY-V*E 515
+KRE +FITTKLW + E V PAL KSL K QL + PV S + + V E
Sbjct: 74 VKREDLFITTKLWCTCFRPELVKPALEKSLKKLQLDYVDLYIMHYPVPMKSGDNDFPVNE 133
Query: 516 --RYLARHVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDS-GLE-KPSALQIE 680
+ L VDF DTW + + K GL KSIG+SNFN Q++RI++ GL+ KP Q+E
Sbjct: 134 QGKSLLDTVDFCDTWERLEECKDAGLVKSIGVSNFNHRQLERILNKPGLKYKPVCNQVE 192
Score = 49.2 bits (112), Expect = 2e-04
Identities = 28/79 (35%), Positives = 45/79 (56%)
Frame = +2
Query: 146 LQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQV 325
++L+ G IP + GT+ K K V + E A + AL+ GY H+DTAY Y +E+++
Sbjct: 8 VKLNDGHLIPALGFGTY-----KPKEVPKSKSLEAACL-ALDVGYRHVDTAYAYQVEEEI 61
Query: 326 GRALXQEILRRT*KRIYLY 382
G+A+ +I KR L+
Sbjct: 62 GQAIQSKIKAGVVKREDLF 80
>UniRef50_Q54B70 Cluster: Aldehyde reductase; n=2; Dictyostelium
discoideum|Rep: Aldehyde reductase - Dictyostelium
discoideum AX4
Length = 297
Score = 73.3 bits (172), Expect = 9e-12
Identities = 46/125 (36%), Positives = 69/125 (55%), Gaps = 11/125 (8%)
Frame = +3
Query: 339 TKKFSEG--LKRESIFITTKLWNSYHEREQVIPALRKSLXKSQLGIRR--------PV-F 485
TKKF+ +KRE +FIT+KLWN++H++E V PAL ++L S LG++ PV F
Sbjct: 60 TKKFTTEATVKREDVFITSKLWNTFHKKEHVRPALERTL--SDLGLQYLDLYLVHWPVAF 117
Query: 486 DSLAHSYV*ERYLARHVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGLEKPS 665
+ ++ V +TW M GL KSIG+SNFN + + ++ KP+
Sbjct: 118 EYTSNDIQTSGSTQEFVSIRETWEEMEKLVDAGLVKSIGLSNFNVQGLMEVLSYARIKPA 177
Query: 666 ALQIE 680
A Q+E
Sbjct: 178 ANQVE 182
Score = 45.2 bits (102), Expect = 0.003
Identities = 29/70 (41%), Positives = 37/70 (52%), Gaps = 1/70 (1%)
Frame = +2
Query: 140 PTLQLSSGGNIPVVALGTWLGHRPK-GKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIE 316
P+ +LSSG IP+V GTW GK V+V AL+AGY HID A Y E
Sbjct: 3 PSFKLSSGHKIPLVGFGTWKAETTLVGKAVEV----------ALDAGYRHIDCAAVYLNE 52
Query: 317 DQVGRALXQE 346
+VG A ++
Sbjct: 53 KEVGEAFTKK 62
>UniRef50_Q0VGY1 Cluster: 3-alpha-hydroxysteroid dehydrogenase;
n=13; Tetrapoda|Rep: 3-alpha-hydroxysteroid
dehydrogenase - Xenopus tropicalis (Western clawed frog)
(Silurana tropicalis)
Length = 324
Score = 72.1 bits (169), Expect = 2e-11
Identities = 47/125 (37%), Positives = 71/125 (56%), Gaps = 13/125 (10%)
Frame = +3
Query: 345 KFSEG-LKRESIFITTKLWNSYHEREQVIPALRKSLXKSQLG------IRRPVF----DS 491
K ++G +KRE +F T KLW++ H E+V PAL KSL QL I P+ D
Sbjct: 69 KIADGTVKREDVFYTGKLWSTSHTPERVRPALEKSLKDLQLDYMDLFIIHMPMEFKPGDD 128
Query: 492 LAHSYV*ERYLARHVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIID-SGLE-KPS 665
L + +++ + D DTW+ + K GL +SIG+SNFN +Q++ I++ GL+ KP
Sbjct: 129 LFPADENGKFIYHNTDLRDTWKALEKCKDAGLVRSIGVSNFNHKQLELILNMPGLKYKPV 188
Query: 666 ALQIE 680
Q+E
Sbjct: 189 CNQVE 193
Score = 47.2 bits (107), Expect = 7e-04
Identities = 27/76 (35%), Positives = 42/76 (55%), Gaps = 1/76 (1%)
Frame = +2
Query: 146 LQLSSGGNIPVVALGTWLGHR-PKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQ 322
++L+ G +PV+ GT+ + PK E+ A++ GY HID A+ YG E++
Sbjct: 9 VELNDGHKMPVIGFGTYAPPKFPKSLA-------EEGTKVAIDVGYRHIDCAFLYGNEEE 61
Query: 323 VGRALXQEILRRT*KR 370
VGRA+ +I T KR
Sbjct: 62 VGRAIRAKIADGTVKR 77
>UniRef50_A3U9Y0 Cluster: Aldehyde reductase; n=5;
Bacteroidetes|Rep: Aldehyde reductase - Croceibacter
atlanticus HTCC2559
Length = 316
Score = 71.7 bits (168), Expect = 3e-11
Identities = 45/120 (37%), Positives = 68/120 (56%), Gaps = 10/120 (8%)
Frame = +3
Query: 351 SEGLKRESIFITTKLWNSYHEREQVIPALRKSLXKSQLG------IRRPV-FDSLAHSY- 506
S +KRE IF+T+KLWN+ H++E VIPAL+K+L L + PV F + +
Sbjct: 64 SGNVKREDIFVTSKLWNNAHKKEDVIPALKKTLKDLNLDYLDLYLMHWPVAFKPSVNGFP 123
Query: 507 -V*ERYLA-RHVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGLEKPSALQIE 680
E YL+ +T MI+AKK GL K +G+SNF++E+++ + E P Q+E
Sbjct: 124 EKDEDYLSLEEAPLHETLNAMIEAKKQGLIKHVGVSNFSKEKLESLKGKVEEMPEMNQVE 183
Score = 45.6 bits (103), Expect = 0.002
Identities = 27/67 (40%), Positives = 33/67 (49%)
Frame = +2
Query: 143 TLQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQ 322
TL+ G +IP + LGTW D ++AV ALE GY HID A Y ED
Sbjct: 3 TLKFRDGDSIPSIGLGTWKSD---------PEDVKKAVKIALENGYKHIDCAAAYDNEDA 53
Query: 323 VGRALXQ 343
VG A +
Sbjct: 54 VGEAFKE 60
>UniRef50_Q5BKE9 Cluster: LOC594893 protein; n=5; Xenopus
tropicalis|Rep: LOC594893 protein - Xenopus tropicalis
(Western clawed frog) (Silurana tropicalis)
Length = 345
Score = 71.3 bits (167), Expect = 3e-11
Identities = 47/126 (37%), Positives = 70/126 (55%), Gaps = 13/126 (10%)
Frame = +3
Query: 342 KKFSEG-LKRESIFITTKLWNSYHEREQVIPALRKSLXKSQLG------IRRPVFDSLAH 500
+KF++G LKRE +F T+KLWN++H+ V PAL K+L Q+ I P+ A
Sbjct: 89 EKFADGTLKREDLFYTSKLWNTFHQPHLVRPALEKTLSFLQMDYVDLYLIHMPMSFKPAE 148
Query: 501 SYV*ERYLAR----HVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDS-GLE-KP 662
+ D L TW+ + + + GL KSIG+SNFN+ Q++ I++ GL+ KP
Sbjct: 149 ELFPKNEDGTCAFDQPDLLQTWQALEECRDAGLVKSIGVSNFNRRQLEMILNKPGLKYKP 208
Query: 663 SALQIE 680
QIE
Sbjct: 209 VCNQIE 214
Score = 36.7 bits (81), Expect = 0.92
Identities = 30/95 (31%), Positives = 42/95 (44%), Gaps = 15/95 (15%)
Frame = +2
Query: 143 TLQLSSGGNIPVVALGTWL------------GH---RPKGKVVQVTNDTEQAVIYALEAG 277
++QL G +PVVA GT+ GH G +D A AL+ G
Sbjct: 8 SIQLHDGRWMPVVAFGTFYPFTFPGDSQANPGHCAGTKHGTEKSFIDDVRVATKMALDLG 67
Query: 278 YTHIDTAYKYGIEDQVGRALXQEILRRT*KRIYLY 382
Y H+D A+ Y E VG+A ++ T KR L+
Sbjct: 68 YRHVDGAFLYSSETGVGQAFREKFADGTLKREDLF 102
>UniRef50_Q8K023 Cluster: Aldo-keto reductase family 1 member C18;
n=72; Tetrapoda|Rep: Aldo-keto reductase family 1 member
C18 - Mus musculus (Mouse)
Length = 323
Score = 68.5 bits (160), Expect = 2e-10
Identities = 48/125 (38%), Positives = 66/125 (52%), Gaps = 13/125 (10%)
Frame = +3
Query: 345 KFSEG-LKRESIFITTKLWNSYHEREQVIPALRKSLXKSQLG------IRRPVFDSLAHS 503
K +G +KRE IF T+KLW++ H E V P+L SL K L I PV +
Sbjct: 68 KIEDGTVKREDIFYTSKLWSTSHRPELVRPSLENSLRKLNLDYVDLYLIHFPVSLKPGNE 127
Query: 504 YV*E----RYLARHVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDS-GLE-KPS 665
+ + + VD DTW M K GL KSIG+SNFN+ Q++ I++ GL+ KP
Sbjct: 128 LLPKDEHGNLIFDTVDLCDTWEAMEKCKDAGLAKSIGVSNFNRRQLEMILNKPGLKYKPV 187
Query: 666 ALQIE 680
Q+E
Sbjct: 188 CNQVE 192
Score = 38.7 bits (86), Expect = 0.23
Identities = 20/78 (25%), Positives = 42/78 (53%)
Frame = +2
Query: 137 VPTLQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIE 316
+ ++L+ G +IPV+ GT+ + + ++ A++ G+ HID ++ Y E
Sbjct: 5 IQKIELNDGHSIPVLGFGTYATEE------HLKKKSMESTKIAIDVGFCHIDCSHLYQNE 58
Query: 317 DQVGRALXQEILRRT*KR 370
+++G+A+ +I T KR
Sbjct: 59 EEIGQAILSKIEDGTVKR 76
Score = 36.7 bits (81), Expect = 0.92
Identities = 15/27 (55%), Positives = 21/27 (77%)
Frame = +1
Query: 448 LXNLNLEYVDLYLIHWPIAMFENDTLL 528
L LNL+YVDLYLIH+P+++ + LL
Sbjct: 103 LRKLNLDYVDLYLIHFPVSLKPGNELL 129
>UniRef50_Q7ZWA4 Cluster: Zgc:56622; n=6; cellular organisms|Rep:
Zgc:56622 - Danio rerio (Zebrafish) (Brachydanio rerio)
Length = 289
Score = 68.1 bits (159), Expect = 3e-10
Identities = 42/123 (34%), Positives = 61/123 (49%), Gaps = 11/123 (8%)
Frame = +3
Query: 345 KFSEGL-KRESIFITTKLWNSYHEREQVIPALRKSLXKSQLG------IRRPV-FDSLAH 500
K +G+ +R+ +FI +KLW ++H E + KSL QL + PV +
Sbjct: 36 KIQQGIIRRQDMFIVSKLWGTHHAPEDIPVCFNKSLSDLQLDYLDQYLVHFPVGLKKVGD 95
Query: 501 SYV*ER---YLARHVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGLEKPSAL 671
ER L +D++D WRGM K G KSIG+SNF EQI R++ P+
Sbjct: 96 ELFPERDGKILTTDIDYVDVWRGMEALKATGKVKSIGVSNFTMEQIDRLLSVAKIPPAVN 155
Query: 672 QIE 680
Q+E
Sbjct: 156 QVE 158
>UniRef50_Q2LZ66 Cluster: GA19341-PA; n=2; Endopterygota|Rep:
GA19341-PA - Drosophila pseudoobscura (Fruit fly)
Length = 315
Score = 68.1 bits (159), Expect = 3e-10
Identities = 45/125 (36%), Positives = 68/125 (54%), Gaps = 12/125 (9%)
Frame = +3
Query: 342 KKFSEGL-KRESIFITTKLWNSYHEREQVIPALRKSLXKSQLG------IRRPV-FDSLA 497
+K EGL R+ +FIT+KLWN++H+ E V A SL + + P+ + S
Sbjct: 62 EKIQEGLVTRDELFITSKLWNTFHKPELVRAACETSLRNLGIDYLDLYLMHWPMAYKSGD 121
Query: 498 HSYV*----ERYLARHVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGLEKPS 665
+ Y + + +D+LDTW+ M D GL +IG+SNFN++QI R++ KP
Sbjct: 122 NLYPTCPDTGKAVFEDIDYLDTWKAMEDLVDSGLVNAIGVSNFNEKQINRLLCLAKLKPV 181
Query: 666 ALQIE 680
LQIE
Sbjct: 182 MLQIE 186
Score = 49.2 bits (112), Expect = 2e-04
Identities = 31/70 (44%), Positives = 41/70 (58%)
Frame = +2
Query: 140 PTLQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIED 319
P+ LSSG N+P+V LGTW R +VV QAV A++ GY H D A+ YG E
Sbjct: 4 PSFLLSSGRNMPMVGLGTW---RSPPEVVA------QAVKDAIDIGYRHFDCAHIYGNEL 54
Query: 320 QVGRALXQEI 349
VG A+ ++I
Sbjct: 55 HVGVAIREKI 64
Score = 39.1 bits (87), Expect = 0.17
Identities = 15/29 (51%), Positives = 20/29 (68%)
Frame = +1
Query: 448 LXNLNLEYVDLYLIHWPIAMFENDTLLDT 534
L NL ++Y+DLYL+HWP+A D L T
Sbjct: 98 LRNLGIDYLDLYLMHWPMAYKSGDNLYPT 126
>UniRef50_Q7QK25 Cluster: ENSANGP00000019775; n=2; Anopheles gambiae
str. PEST|Rep: ENSANGP00000019775 - Anopheles gambiae
str. PEST
Length = 319
Score = 67.7 bits (158), Expect = 4e-10
Identities = 43/128 (33%), Positives = 70/128 (54%), Gaps = 16/128 (12%)
Frame = +3
Query: 345 KFSEG-LKRESIFITTKLWNSYHEREQVIPALRKSLXKSQLG------IRRPV---FDSL 494
K +EG ++RE +F+TTKLWN++H+ + V A R+S +G + P+ F
Sbjct: 65 KIAEGVIRREDVFVTTKLWNTFHDPQHVEEAFRRSFDMLDIGYIDLFLMHSPMGVQFSGY 124
Query: 495 AHSYV*ERYLARH-----VDFLDTWRGMIDAKKLG-LTKSIGISNFNQEQIQRIIDSGLE 656
++ + + A + VD+++TW+ M G +SIG+SNFN EQI+RI+
Sbjct: 125 EYADMQPKDAAGNMLFSDVDYVETWKAMEKLVTAGGRVRSIGLSNFNSEQIERILQIATV 184
Query: 657 KPSALQIE 680
KP Q+E
Sbjct: 185 KPVNNQVE 192
Score = 49.2 bits (112), Expect = 2e-04
Identities = 27/71 (38%), Positives = 43/71 (60%)
Frame = +2
Query: 137 VPTLQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIE 316
VPT++ S+G IPV+ GT+L KG+ V++ A++ GY HIDTA+ Y E
Sbjct: 5 VPTVRFSNGYEIPVLGYGTYLAQ--KGQCVELVKK-------AIDLGYRHIDTAFLYENE 55
Query: 317 DQVGRALXQEI 349
++G+A+ +I
Sbjct: 56 VEIGQAIRDKI 66
>UniRef50_A2EHN6 Cluster: Oxidoreductase, aldo/keto reductase family
protein; n=10; Trichomonas vaginalis|Rep:
Oxidoreductase, aldo/keto reductase family protein -
Trichomonas vaginalis G3
Length = 312
Score = 67.3 bits (157), Expect = 6e-10
Identities = 46/126 (36%), Positives = 72/126 (57%), Gaps = 15/126 (11%)
Frame = +3
Query: 348 FSEG-LKRESIFITTKLWNSYHEREQVIPALRKSLXKSQLG------IRRPV-FDSLAHS 503
F++G +KRE +FITTKLW ++H ++ V P L ++L + QL I +P+ F SL
Sbjct: 55 FAKGKIKREDMFITTKLWCTHHRKDLVEPELHENLAQLQLSYVDLFLIHQPIAFKSLPAK 114
Query: 504 Y-------V*ERYLARHVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGLEKP 662
+ +D L+T+ M + +K GLT+ IG+SNF+ EQ++RI + KP
Sbjct: 115 DGTMMPKDEKGKIQYEQIDILETYHAMEECQKKGLTRHIGVSNFSIEQLERIWFNCEIKP 174
Query: 663 SALQIE 680
A Q+E
Sbjct: 175 YANQVE 180
>UniRef50_Q7PCV3 Cluster: ENSANGP00000031808; n=9;
Endopterygota|Rep: ENSANGP00000031808 - Anopheles
gambiae str. PEST
Length = 316
Score = 66.9 bits (156), Expect = 8e-10
Identities = 42/124 (33%), Positives = 66/124 (53%), Gaps = 12/124 (9%)
Frame = +3
Query: 345 KFSEGL-KRESIFITTKLWNSYHEREQVIPALRKSLXKSQLG------IRRPV-----FD 488
K +EG+ KRE +F+T+KLWN++H + V A + +L +L I PV +
Sbjct: 66 KIAEGVVKREDLFVTSKLWNTFHRPDLVEGACKTTLQNLKLDYLDLYLIHWPVGYQEGTE 125
Query: 489 SLAHSYV*ERYLARHVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGLEKPSA 668
+ +L D++DTW M GL ++IG+SNFN +Q+QR++D P+
Sbjct: 126 LFPMGPDGKTFLFSDADYVDTWPEMEKLVDAGLVRNIGVSNFNAKQVQRVLDVARIPPAT 185
Query: 669 LQIE 680
QIE
Sbjct: 186 NQIE 189
Score = 50.4 bits (115), Expect = 7e-05
Identities = 29/83 (34%), Positives = 42/83 (50%)
Frame = +2
Query: 134 IVPTLQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGI 313
+VP +G +IP+ LGTW + P G+V Q D A++ GY HID A+ Y
Sbjct: 5 VVPNAIFKNGNSIPMFGLGTW--NSPPGQVAQAVKD-------AIDVGYRHIDCAHVYQN 55
Query: 314 EDQVGRALXQEILRRT*KRIYLY 382
E +VG + +I KR L+
Sbjct: 56 EHEVGEGIAAKIAEGVVKREDLF 78
Score = 37.9 bits (84), Expect = 0.40
Identities = 15/26 (57%), Positives = 18/26 (69%)
Frame = +1
Query: 448 LXNLNLEYVDLYLIHWPIAMFENDTL 525
L NL L+Y+DLYLIHWP+ E L
Sbjct: 101 LQNLKLDYLDLYLIHWPVGYQEGTEL 126
>UniRef50_Q9VTL0 Cluster: CG6083-PA; n=4; Diptera|Rep: CG6083-PA -
Drosophila melanogaster (Fruit fly)
Length = 322
Score = 66.5 bits (155), Expect = 1e-09
Identities = 43/128 (33%), Positives = 70/128 (54%), Gaps = 15/128 (11%)
Frame = +3
Query: 342 KKFSEGL-KRESIFITTKLWNSYHEREQVIPALRKSLXKSQLGIR-------------RP 479
+K EG+ R+ +FIT+KLWN++H+ + V PA S+ LG++ +
Sbjct: 62 EKMDEGVVTRDELFITSKLWNTHHKPDLVRPACETSIRN--LGVKYLNLYLMHWPMAYKS 119
Query: 480 VFDSLAHSYV*ERYLA-RHVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGLE 656
D+L + A +D++DTWR M + GL ++IG+SNFN++Q+ R++
Sbjct: 120 GSDNLYPTCPDTNKAAFEDIDYVDTWRAMENLVDEGLCQAIGVSNFNEQQMNRLLSVAKL 179
Query: 657 KPSALQIE 680
KP LQIE
Sbjct: 180 KPVVLQIE 187
Score = 49.6 bits (113), Expect = 1e-04
Identities = 30/70 (42%), Positives = 41/70 (58%)
Frame = +2
Query: 140 PTLQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIED 319
P LS+G N+P++ LGTW R +VV QAV A++ GY H D A+ YG E
Sbjct: 4 PNFLLSNGKNMPMLGLGTW---RSPPEVVT------QAVKDAIDIGYRHFDCAHIYGNEA 54
Query: 320 QVGRALXQEI 349
QVG AL +++
Sbjct: 55 QVGAALREKM 64
>UniRef50_Q9NAI5 Cluster: Putative uncharacterized protein; n=3;
Caenorhabditis|Rep: Putative uncharacterized protein -
Caenorhabditis elegans
Length = 316
Score = 65.3 bits (152), Expect = 2e-09
Identities = 40/117 (34%), Positives = 60/117 (51%), Gaps = 10/117 (8%)
Frame = +3
Query: 360 LKRESIFITTKLWNSYHEREQVIPALRKSLXKSQLGIRRPVFDSLAHSYV*--------E 515
+KRE +FIT+K+WN++H + + L QL + Y E
Sbjct: 68 VKREELFITSKVWNTFHSEAKAHENIDIILSDLQLSYVDLMLIHWPQGYAEGAELFPAGE 127
Query: 516 RYLARH--VDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGLEKPSALQIE 680
R+ VD+L+TW+ A+K G +SIG+SNF QIQR+ D+ KP+ LQ+E
Sbjct: 128 NGKMRYSDVDYLETWKAFEAAQKAGKCRSIGLSNFTHSQIQRVWDAAEVKPACLQVE 184
Score = 46.0 bits (104), Expect = 0.002
Identities = 31/73 (42%), Positives = 45/73 (61%)
Frame = +2
Query: 134 IVPTLQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGI 313
+V +L+L+SG +IP + LGTW +P G+V A+ A+ AGY HID A+ Y
Sbjct: 1 MVQSLKLNSGYSIPAIGLGTWQS-KP-GEVAA-------AIKTAVAAGYRHIDCAHVYQN 51
Query: 314 EDQVGRALXQEIL 352
+ +VG AL +EIL
Sbjct: 52 QKEVGEAL-KEIL 63
>UniRef50_Q6TY50 Cluster: Reductase 2; n=10; Magnoliophyta|Rep:
Reductase 2 - Hydrangea macrophylla (Bigleaf hydrangea)
Length = 321
Score = 64.9 bits (151), Expect = 3e-09
Identities = 41/118 (34%), Positives = 65/118 (55%), Gaps = 9/118 (7%)
Frame = +3
Query: 354 EGL--KRESIFITTKLWNSYHEREQVIPALRKSLXKSQLG------IRRPVFDSLA-HSY 506
EGL R+ +FIT+KLW S RE V PAL+K+L +L I PV + Y
Sbjct: 72 EGLIKSRDELFITSKLWCSDAHRENVEPALQKTLKNLKLEYIDMYLIHWPVSSKPGNYEY 131
Query: 507 V*ERYLARHVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGLEKPSALQIE 680
++ +D+ W M + +KLGLTK+IG+SNF+ +++ ++ + P+ Q+E
Sbjct: 132 PIKKEDFLQMDYKSVWEAMEECQKLGLTKAIGVSNFSCKKLSDVLANAKVPPAVNQVE 189
Score = 39.5 bits (88), Expect = 0.13
Identities = 26/72 (36%), Positives = 38/72 (52%), Gaps = 1/72 (1%)
Frame = +2
Query: 137 VPTLQLSSGGN-IPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGI 313
+P + LSSGG +PV+ LGT + V+ +AV AL+ GY H DTA Y
Sbjct: 5 IPEVPLSSGGRKMPVLGLGTAADPPVDPETVR------KAVTEALKLGYRHFDTAALYNS 58
Query: 314 EDQVGRALXQEI 349
E +G A+ + +
Sbjct: 59 EQPLGDAIAEAL 70
>UniRef50_Q5FT75 Cluster: Putative 2,5-diketo-D-gluconic acid
reductase; n=1; Gluconobacter oxydans|Rep: Putative
2,5-diketo-D-gluconic acid reductase - Gluconobacter
oxydans (Gluconobacter suboxydans)
Length = 279
Score = 64.5 bits (150), Expect = 4e-09
Identities = 37/102 (36%), Positives = 57/102 (55%)
Frame = +3
Query: 375 IFITTKLWNSYHEREQVIPALRKSLXKSQLGIRRPVFDSLAHSYV*ERYLARHVDFLDTW 554
IF+TTKLWN EQ + ++ +S +RRPV D Y+ + +++TW
Sbjct: 74 IFLTTKLWND----EQGYDSTLRAYEESARLLRRPVLDL----YLIHWPMPAQGQYVETW 125
Query: 555 RGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGLEKPSALQIE 680
+ +++ KK G KSIG+SNF E ++RI+D+ P QIE
Sbjct: 126 KALVELKKSGRVKSIGVSNFESEHLERIMDATGVVPVVNQIE 167
>UniRef50_Q7JVH6 Cluster: LD24696p; n=2; Sophophora|Rep: LD24696p -
Drosophila melanogaster (Fruit fly)
Length = 311
Score = 64.5 bits (150), Expect = 4e-09
Identities = 47/124 (37%), Positives = 66/124 (53%), Gaps = 10/124 (8%)
Frame = +3
Query: 339 TKKFSEGL-KRESIFITTKLWNSYHEREQVIPALRKSLXKSQLGIR--------RPVFDS 491
++K +EG+ RE +F+TTKL +H+ V A R SL S LG+ PV
Sbjct: 63 SEKIAEGVVTREEVFVTTKLGGIHHDPALVERACRLSL--SNLGLEYVDLYLMHMPVGQK 120
Query: 492 LAH-SYV*ERYLARHVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGLEKPSA 668
+ S V VD+LDTWR M LGLT+SIG+SNFN Q +R++ + +P
Sbjct: 121 FHNDSNVHGTLELTDVDYLDTWREMEKLVDLGLTRSIGLSNFNAAQTERVLANCRIRPVV 180
Query: 669 LQIE 680
Q+E
Sbjct: 181 NQVE 184
Score = 50.4 bits (115), Expect = 7e-05
Identities = 24/72 (33%), Positives = 42/72 (58%)
Frame = +2
Query: 134 IVPTLQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGI 313
+ PT++L++G +P + LGTW +D + +AL+ GY H+DTA+ Y
Sbjct: 4 LAPTIRLNNGREMPTLGLGTWKSFE---------SDAYHSTRHALDVGYRHLDTAFVYEN 54
Query: 314 EDQVGRALXQEI 349
E +VG+A+ ++I
Sbjct: 55 EAEVGQAISEKI 66
>UniRef50_A2FPE2 Cluster: Oxidoreductase, aldo/keto reductase family
protein; n=3; Trichomonas vaginalis G3|Rep:
Oxidoreductase, aldo/keto reductase family protein -
Trichomonas vaginalis G3
Length = 309
Score = 63.7 bits (148), Expect = 7e-09
Identities = 42/126 (33%), Positives = 73/126 (57%), Gaps = 15/126 (11%)
Frame = +3
Query: 348 FSEG-LKRESIFITTKLWNSYHEREQVIPALRKSLXKSQLGIRRPVFDSLA---HSYV*E 515
F++G +KRE ++IT+K+WN+ H + ++ ++K+L + +L V A S +
Sbjct: 56 FAKGQVKREEVWITSKVWNTKHRPDLLVKDVKKTLKELKLEYLDLVLVHWACAFQSREDD 115
Query: 516 RYLAR---------HVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRI-IDSGLE-KP 662
YL R ++D L+TW+ M + LGL K IG+SNF+ EQ++R+ D G++ +P
Sbjct: 116 EYLPRDETGKIITENIDILETWKAMEECYNLGLAKHIGVSNFSIEQLERMRYDPGVKIQP 175
Query: 663 SALQIE 680
Q+E
Sbjct: 176 YCNQVE 181
>UniRef50_P45376 Cluster: Aldose reductase; n=21; Bilateria|Rep:
Aldose reductase - Mus musculus (Mouse)
Length = 316
Score = 63.3 bits (147), Expect = 9e-09
Identities = 43/119 (36%), Positives = 62/119 (52%), Gaps = 12/119 (10%)
Frame = +3
Query: 360 LKRESIFITTKLWNSYHEREQVIPALRKSLXKSQLG------IRRPVFDSLAHSY----V 509
+KR+ +FI +KLW ++H++ V A +K+L QL I P Y
Sbjct: 68 VKRQDLFIVSKLWCTFHDKSMVKGAFQKTLSDLQLDYLDLYLIHWPTGFKPGPDYFPLDA 127
Query: 510 *ERYLARHVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDS-GLE-KPSALQIE 680
+ DF+DTW M GL K+IG+SNFN QI+RI++ GL+ KP+ QIE
Sbjct: 128 SGNVIPSDTDFVDTWTAMEQLVDEGLVKTIGVSNFNPLQIERILNKPGLKYKPAVNQIE 186
Score = 46.8 bits (106), Expect = 9e-04
Identities = 29/79 (36%), Positives = 44/79 (55%)
Frame = +2
Query: 146 LQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQV 325
L+L++G +P + LGTW P G+V + AV A++ GY HID A Y E +V
Sbjct: 5 LELNNGTKMPTLGLGTWKS--PPGQVTE-------AVKVAIDLGYRHIDCAQVYQNEKEV 55
Query: 326 GRALXQEILRRT*KRIYLY 382
G AL +++ + KR L+
Sbjct: 56 GVALQEKLKEQVVKRQDLF 74
Score = 33.5 bits (73), Expect = 8.6
Identities = 12/17 (70%), Positives = 15/17 (88%)
Frame = +1
Query: 448 LXNLNLEYVDLYLIHWP 498
L +L L+Y+DLYLIHWP
Sbjct: 97 LSDLQLDYLDLYLIHWP 113
>UniRef50_Q17DN0 Cluster: Aldo-keto reductase; n=5; Culicidae|Rep:
Aldo-keto reductase - Aedes aegypti (Yellowfever
mosquito)
Length = 324
Score = 62.9 bits (146), Expect = 1e-08
Identities = 44/127 (34%), Positives = 64/127 (50%), Gaps = 15/127 (11%)
Frame = +3
Query: 345 KFSEGL-KRESIFITTKLWNSYHEREQVIPALRKSLXKSQLG------IRRPV------F 485
K EG+ RE +F+TTKLWN++H + V A KSL L I P +
Sbjct: 66 KIEEGVVTREELFVTTKLWNTFHHPDHVPMAFGKSLEHLGLDYVDLFLIHMPFGYEFNGW 125
Query: 486 DSLAHSYV*ER--YLARHVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGLEK 659
D + + + L D++DTW+ M + G SIG+SNFN EQ++RI+ + K
Sbjct: 126 DPEKRTPLDDNGNVLCSDDDYVDTWKAMEKLLESGRVHSIGVSNFNSEQLERILANCRVK 185
Query: 660 PSALQIE 680
P Q+E
Sbjct: 186 PVTNQVE 192
Score = 50.4 bits (115), Expect = 7e-05
Identities = 28/71 (39%), Positives = 45/71 (63%)
Frame = +2
Query: 137 VPTLQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIE 316
+PT++L++G +P + LGT + KG ++ +AV+ A++ G+ HIDTAY Y E
Sbjct: 6 IPTVKLNNGLEMPAIGLGTSMS---KG------DECCKAVMTAIDEGFRHIDTAYNYRNE 56
Query: 317 DQVGRALXQEI 349
D VGRA+ +I
Sbjct: 57 DVVGRAIRAKI 67
>UniRef50_P27800 Cluster: Aldehyde reductase 1; n=18; root|Rep:
Aldehyde reductase 1 - Sporobolomyces salmonicolor
Length = 323
Score = 62.5 bits (145), Expect = 2e-08
Identities = 44/123 (35%), Positives = 62/123 (50%), Gaps = 15/123 (12%)
Frame = +3
Query: 357 GLKRESIFITTKLWNSYHEREQVIPALRKSLXKSQLG------IRRPVF---------DS 491
G+KRE +FIT+KLWN+ H EQV PAL +L + L I PV +
Sbjct: 63 GVKREDLFITSKLWNNSHRPEQVEPALDDTLKELGLEYLDLYLIHWPVAFPPEGDITQNL 122
Query: 492 LAHSYV*ERYLARHVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGLEKPSAL 671
+ E L V +DTW+ M+ G K+IG+SNF+ + + II++ PS
Sbjct: 123 FPKANDKEVKLDLEVSLVDTWKAMVKLLDTGKVKAIGVSNFDAKMVDAIIEATGVTPSVN 182
Query: 672 QIE 680
QIE
Sbjct: 183 QIE 185
Score = 38.3 bits (85), Expect = 0.30
Identities = 22/75 (29%), Positives = 37/75 (49%)
Frame = +2
Query: 134 IVPTLQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGI 313
+V T L++G ++ +V GTW + Q V A+E GY H+D A Y
Sbjct: 1 MVGTTTLNTGASLELVGYGTWQA---------APGEVGQGVKVAIETGYRHLDLAKVYSN 51
Query: 314 EDQVGRALXQEILRR 358
+ +VG A+ + ++R
Sbjct: 52 QPEVGAAIKEAGVKR 66
Score = 37.1 bits (82), Expect = 0.70
Identities = 14/19 (73%), Positives = 16/19 (84%)
Frame = +1
Query: 448 LXNLNLEYVDLYLIHWPIA 504
L L LEY+DLYLIHWP+A
Sbjct: 93 LKELGLEYLDLYLIHWPVA 111
>UniRef50_Q03TW0 Cluster: Aldo/keto reductase of diketogulonate
reductase family; n=1; Lactobacillus brevis ATCC
367|Rep: Aldo/keto reductase of diketogulonate reductase
family - Lactobacillus brevis (strain ATCC 367 / JCM
1170)
Length = 293
Score = 61.7 bits (143), Expect = 3e-08
Identities = 43/122 (35%), Positives = 64/122 (52%), Gaps = 2/122 (1%)
Frame = +3
Query: 321 KWEGPXTKKFSEGLKRESIFITTKLWNSYHEREQVIPALRKSLXKSQLGIRRPVFDSLAH 500
+W G ++ + R+ IF+T+KLWNS ++ A +++L K LG+
Sbjct: 63 QWVGEAIRE--SDVPRDQIFVTSKLWNSVRGYDETQAAFQETLDK--LGL---------- 108
Query: 501 SYV*ERYLARHV--DFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGLEKPSALQ 674
Y+ + YL +LD+WR M D K G K+IG+SNFNQ Q+ I+ G KP Q
Sbjct: 109 DYL-DLYLIHWPAPGYLDSWRAMEDLYKAGKIKNIGVSNFNQTQMADILAHGTVKPVVDQ 167
Query: 675 IE 680
IE
Sbjct: 168 IE 169
Score = 48.4 bits (110), Expect = 3e-04
Identities = 28/74 (37%), Positives = 40/74 (54%)
Frame = +2
Query: 137 VPTLQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIE 316
+P L +++G IP + LG + V DT+ A+ +AL AGY HIDTA YG E
Sbjct: 11 IPDLPMNNGHQIPQLGLGVFQ--------VDNAEDTKNAIKWALAAGYRHIDTAAYYGNE 62
Query: 317 DQVGRALXQEILRR 358
VG A+ + + R
Sbjct: 63 QWVGEAIRESDVPR 76
>UniRef50_Q23320 Cluster: Putative uncharacterized protein; n=4;
Caenorhabditis|Rep: Putative uncharacterized protein -
Caenorhabditis elegans
Length = 320
Score = 61.7 bits (143), Expect = 3e-08
Identities = 44/112 (39%), Positives = 57/112 (50%), Gaps = 1/112 (0%)
Frame = +3
Query: 348 FSEG-LKRESIFITTKLWNSYHEREQVIPALRKSLXKSQLGIRRPVFDSLAHSYV*ERYL 524
F+EG LKRE IFITTK + + V ALR SL + +L + S +
Sbjct: 66 FAEGILKREDIFITTKAFCHEVAPDVVEEALRNSLKRLRLDYVDLYLAHIPASTKDDGSF 125
Query: 525 ARHVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGLEKPSALQIE 680
V D WRG LGLTK+IG+SNFN+ QI RI++ A Q+E
Sbjct: 126 RSDVKVEDIWRGFEKVYGLGLTKAIGVSNFNESQIVRIMNIQKVPIHASQLE 177
Score = 44.0 bits (99), Expect = 0.006
Identities = 29/69 (42%), Positives = 37/69 (53%)
Frame = +2
Query: 137 VPTLQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIE 316
VP LS+G +P + LGTW +GK V + N A+ AGY HIDTA Y E
Sbjct: 5 VPIFTLSNGVLMPSIGLGTWQMTGEEGKTV-IRN--------AVLAGYRHIDTATLYQNE 55
Query: 317 DQVGRALXQ 343
Q+G AL +
Sbjct: 56 HQIGDALAE 64
>UniRef50_A3C1Z7 Cluster: Putative uncharacterized protein; n=2;
Oryza sativa (japonica cultivar-group)|Rep: Putative
uncharacterized protein - Oryza sativa subsp. japonica
(Rice)
Length = 288
Score = 61.3 bits (142), Expect = 4e-08
Identities = 36/114 (31%), Positives = 64/114 (56%), Gaps = 9/114 (7%)
Frame = +3
Query: 366 RESIFITTKLWNSYHEREQVIPALRKSLXKSQLG------IRRPVFDSLAHSYV*ERYLA 527
R+ ++IT+KLW ++ V+P+LR++L K Q+ I PV LA Y
Sbjct: 75 RDELYITSKLWVAHAHPGHVLPSLRRALRKMQMEYLDLYLIHFPVSMRLAEDPESMTYSK 134
Query: 528 RHVDFLD---TWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGLEKPSALQIE 680
+ +D W+ M + ++LGLTK+IG+SNF+ ++++ ++ P+A Q+E
Sbjct: 135 DDLVMMDMEGVWKEMEECQRLGLTKAIGVSNFSCKKLETLLSFATISPAANQVE 188
Score = 39.5 bits (88), Expect = 0.13
Identities = 26/71 (36%), Positives = 36/71 (50%)
Frame = +2
Query: 137 VPTLQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIE 316
+P LSSG +P V +GT P G T + V+ A+EAGY H DTA Y E
Sbjct: 1 MPEAALSSGKPMPRVGMGT--ASFPLGATDPST--VKDVVLRAIEAGYRHFDTAAVYQTE 56
Query: 317 DQVGRALXQEI 349
+G A+ + +
Sbjct: 57 AILGDAVAEAV 67
>UniRef50_Q2S340 Cluster: Aldehyde reductase; n=10; Bacteria|Rep:
Aldehyde reductase - Salinibacter ruber (strain DSM
13855)
Length = 321
Score = 60.9 bits (141), Expect = 5e-08
Identities = 37/117 (31%), Positives = 63/117 (53%), Gaps = 9/117 (7%)
Frame = +3
Query: 357 GLKRESIFITTKLWNSYHEREQVIPALRKSLXKSQLG------IRRPVF--DSLAHSYV* 512
G++R+ +++T+KLWN+ H + V PAL ++L +L I PV +
Sbjct: 66 GIRRDDVWVTSKLWNNAHHPDDVRPALEQTLSDLRLDALDLYLIHWPVALQPEVDFPESP 125
Query: 513 ERYLARH-VDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGLEKPSALQIE 680
+ +++ V +TW M KK GL + IG+SNF+ +Q I+D+G +P Q+E
Sbjct: 126 DDFVSPEAVPLTETWAAMEALKKDGLVRHIGVSNFSVPNLQMILDAGEVRPEMNQVE 182
Score = 44.4 bits (100), Expect = 0.005
Identities = 26/65 (40%), Positives = 36/65 (55%)
Frame = +2
Query: 143 TLQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQ 322
++ +G +P++ LGTW P G+V + AV ALEAGY H+D A Y E +
Sbjct: 3 SISFENGDEMPMIGLGTWKS--PPGEVYE-------AVTTALEAGYRHVDCAPIYKNETE 53
Query: 323 VGRAL 337
VG AL
Sbjct: 54 VGAAL 58
Score = 33.5 bits (73), Expect = 8.6
Identities = 12/20 (60%), Positives = 17/20 (85%)
Frame = +1
Query: 448 LXNLNLEYVDLYLIHWPIAM 507
L +L L+ +DLYLIHWP+A+
Sbjct: 96 LSDLRLDALDLYLIHWPVAL 115
>UniRef50_P14550 Cluster: Alcohol dehydrogenase [NADP+]; n=44;
Bilateria|Rep: Alcohol dehydrogenase [NADP+] - Homo
sapiens (Human)
Length = 325
Score = 60.9 bits (141), Expect = 5e-08
Identities = 36/119 (30%), Positives = 61/119 (51%), Gaps = 10/119 (8%)
Frame = +3
Query: 354 EGLKRESIFITTKLWNSYHEREQVIPALRKSLXKSQLGIRRPVFDSLAHSYV-*ERYLAR 530
+ + RE +F+T+KLWN+ H E V PALRK+L QL +++ + +
Sbjct: 68 KAVPREELFVTSKLWNTKHHPEDVEPALRKTLADLQLEYLDLYLMHWPYAFERGDNPFPK 127
Query: 531 HVD---------FLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGLEKPSALQIE 680
+ D + +TW+ + GL +++G+SNFN QI I+ +P+ LQ+E
Sbjct: 128 NADGTICYDSTHYKETWKALEALVAKGLVQALGLSNFNSRQIDDILSVASVRPAVLQVE 186
Score = 47.2 bits (107), Expect = 7e-04
Identities = 27/66 (40%), Positives = 38/66 (57%)
Frame = +2
Query: 152 LSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQVGR 331
L +G +P++ LGTW K + QV + AV YAL GY HID A YG E ++G
Sbjct: 8 LHTGQKMPLIGLGTW-----KSEPGQV----KAAVKYALSVGYRHIDCAAIYGNEPEIGE 58
Query: 332 ALXQEI 349
AL +++
Sbjct: 59 ALKEDV 64
Score = 35.9 bits (79), Expect = 1.6
Identities = 14/24 (58%), Positives = 17/24 (70%)
Frame = +1
Query: 448 LXNLNLEYVDLYLIHWPIAMFEND 519
L +L LEY+DLYL+HWP A D
Sbjct: 99 LADLQLEYLDLYLMHWPYAFERGD 122
>UniRef50_P26690 Cluster: NAD(P)H-dependent 6'-deoxychalcone
synthase; n=3; Papilionoideae|Rep: NAD(P)H-dependent
6'-deoxychalcone synthase - Glycine max (Soybean)
Length = 315
Score = 60.9 bits (141), Expect = 5e-08
Identities = 38/114 (33%), Positives = 60/114 (52%), Gaps = 7/114 (6%)
Frame = +3
Query: 360 LKRESIFITTKLWNSYHEREQVIPALRKSLXKSQLG------IRRPVFDSLAH-SYV*ER 518
+ R+ +F+T+KLW + + V+PALRKSL QL I P+ S+ E
Sbjct: 78 VSRQDLFVTSKLWVTENHPHLVLPALRKSLKTLQLEYLDLYLIHWPLSSQPGKFSFPIEV 137
Query: 519 YLARHVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGLEKPSALQIE 680
D W M + +KLGLTK+IG+SNF+ +++Q ++ +P Q+E
Sbjct: 138 EDLLPFDVKGVWESMEECQKLGLTKAIGVSNFSVKKLQNLLSVATIRPVVDQVE 191
Score = 41.9 bits (94), Expect = 0.024
Identities = 18/37 (48%), Positives = 25/37 (67%)
Frame = +2
Query: 239 DTEQAVIYALEAGYTHIDTAYKYGIEDQVGRALXQEI 349
DT++A+I A++ GY H DTA YG E +G AL + I
Sbjct: 37 DTKEAIIEAVKQGYRHFDTAAAYGSEQALGEALKEAI 73
Score = 35.5 bits (78), Expect = 2.1
Identities = 13/19 (68%), Positives = 16/19 (84%)
Frame = +1
Query: 448 LXNLNLEYVDLYLIHWPIA 504
L L LEY+DLYLIHWP++
Sbjct: 107 LKTLQLEYLDLYLIHWPLS 125
>UniRef50_UPI0000498F1F Cluster: oxidoreductase, aldo/keto reductase
family; n=2; Entamoeba histolytica HM-1:IMSS|Rep:
oxidoreductase, aldo/keto reductase family - Entamoeba
histolytica HM-1:IMSS
Length = 305
Score = 60.5 bits (140), Expect = 7e-08
Identities = 36/109 (33%), Positives = 57/109 (52%), Gaps = 2/109 (1%)
Frame = +3
Query: 360 LKRESIFITTKLWNSYHEREQVIPALRKSLXKSQLGI--RRPVFDSLAHSYV*ERYLARH 533
+KRE +F+TTKLW++ +E V PA +SL K QL + L +
Sbjct: 68 VKREELFVTTKLWSTDKHKEDVRPACLESLKKLQLEYLDLYIIHIPLTADKKTGEFTEEI 127
Query: 534 VDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGLEKPSALQIE 680
+ +TWR M + GL KSIG+SNFN ++++ ++ +P+ Q E
Sbjct: 128 IPIEETWREMEKLVEEGLVKSIGVSNFNIKKLEELLAIAKIQPAVNQFE 176
Score = 41.5 bits (93), Expect = 0.032
Identities = 26/77 (33%), Positives = 38/77 (49%)
Frame = +2
Query: 152 LSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQVGR 331
L++G IP + LGTW+ + +AV A++ GY HID A YG E +VG
Sbjct: 7 LNNGYKIPKLGLGTWMS---------ANGEVGKAVEIAIKNGYRHIDCAKAYGNEKEVGD 57
Query: 332 ALXQEILRRT*KRIYLY 382
+ I + KR L+
Sbjct: 58 GIKSAIAKGYVKREELF 74
>UniRef50_A7CUW0 Cluster: 2,5-didehydrogluconate reductase; n=6;
Bacteria|Rep: 2,5-didehydrogluconate reductase -
Opitutaceae bacterium TAV2
Length = 334
Score = 60.5 bits (140), Expect = 7e-08
Identities = 35/110 (31%), Positives = 57/110 (51%)
Frame = +3
Query: 351 SEGLKRESIFITTKLWNSYHEREQVIPALRKSLXKSQLGIRRPVFDSLAHSYV*ERYLAR 530
+ GL R+ ++ITTK+WNS + + A+R+SL + QL Y+ + +
Sbjct: 118 ASGLPRKELYITTKVWNSAQGYDSTLRAVRESLGRLQL--------EYVDLYLIHWPVPK 169
Query: 531 HVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGLEKPSALQIE 680
++DTW+ + K GL +SIG+SNF +QR+ D P Q+E
Sbjct: 170 IDRYVDTWKALAKIKADGLARSIGVSNFTPVYLQRLFDETGIVPVVNQVE 219
Score = 46.8 bits (106), Expect = 9e-04
Identities = 36/92 (39%), Positives = 47/92 (51%), Gaps = 1/92 (1%)
Frame = +2
Query: 107 ALCFTSADLIVPTLQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYA-LEAGYT 283
A C+T ++PTL LS G +IP + LG W Q+ +D I A AGY
Sbjct: 51 AWCYTMR--MIPTLPLSDGTSIPQLGLGVW----------QMPDDGAGVPIQAAFNAGYR 98
Query: 284 HIDTAYKYGIEDQVGRALXQEILRRT*KRIYL 379
IDTA YG E+ VGRA+ L R K +Y+
Sbjct: 99 AIDTAPIYGNEEGVGRAIRASGLPR--KELYI 128
>UniRef50_Q9U2J5 Cluster: Putative uncharacterized protein; n=2;
Caenorhabditis|Rep: Putative uncharacterized protein -
Caenorhabditis elegans
Length = 339
Score = 60.5 bits (140), Expect = 7e-08
Identities = 39/123 (31%), Positives = 68/123 (55%), Gaps = 16/123 (13%)
Frame = +3
Query: 360 LKRESIFITTKLWNSYHEREQVIPALRKSLXKSQ------LGIRRPVFDSLAHSYV*ERY 521
++RE +F+++K+WN+YH R + + + + L + + I P F ER
Sbjct: 70 VRREELFLSSKIWNTYHSRNRCMQQIDEMLEIFETTYMDLIVIHWP-FGWAEDEPPGERG 128
Query: 522 L--------ARH--VDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGLEKPSAL 671
L R+ VD+L+TW+ + DA + G +SIG++NFN Q++++ GL KP+ L
Sbjct: 129 LWPRGANGKMRYSDVDYLETWKALEDAHRSGKIRSIGLANFNIGQVEQVWTKGLIKPAVL 188
Query: 672 QIE 680
Q+E
Sbjct: 189 QVE 191
Score = 41.5 bits (93), Expect = 0.032
Identities = 24/68 (35%), Positives = 35/68 (51%)
Frame = +2
Query: 134 IVPTLQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGI 313
I T+ L+SG +PV+ GTW PK + D ALEAGY HID+A +
Sbjct: 3 IADTVTLNSGYEMPVIGYGTW--QLPKNLAAERVRD-------ALEAGYRHIDSALSFKN 53
Query: 314 EDQVGRAL 337
+++V +
Sbjct: 54 QEEVAAGI 61
>UniRef50_Q8SSK6 Cluster: ALDOSE REDUCTASE; n=1; Encephalitozoon
cuniculi|Rep: ALDOSE REDUCTASE - Encephalitozoon
cuniculi
Length = 301
Score = 60.5 bits (140), Expect = 7e-08
Identities = 45/124 (36%), Positives = 66/124 (53%), Gaps = 11/124 (8%)
Frame = +3
Query: 342 KKFSEGL-KRESIFITTKLWNSYHEREQVIPALRKSLXKSQLG------IRRPV-FDSLA 497
K F EG+ +R+ +FIT+KLWN++H + LR+SL Q+ I PV FD
Sbjct: 63 KLFDEGVVQRKDLFITSKLWNTFHGCPE--DGLRRSLNDLQMDYVDLYLIHWPVTFDPAP 120
Query: 498 HSYV*---ERYLARHVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGLEKPSA 668
V ++Y D + W+ M LGL KSIGISNF + ++I+ + P+A
Sbjct: 121 DGTVESCGKKYNVGKFDAVGVWKKMEALVDLGLAKSIGISNFGKANTEKILGTCRICPAA 180
Query: 669 LQIE 680
+QIE
Sbjct: 181 IQIE 184
Score = 46.4 bits (105), Expect = 0.001
Identities = 28/69 (40%), Positives = 37/69 (53%)
Frame = +2
Query: 131 LIVPTLQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYG 310
+I T +L++G IP V LGTW G + + E A+ AL GY HIDTA+ YG
Sbjct: 1 MICKTQKLNNGKEIPTVGLGTW-GMEDEAVL-------EGAIRNALSLGYRHIDTAFIYG 52
Query: 311 IEDQVGRAL 337
E +G L
Sbjct: 53 NEKMIGNIL 61
>UniRef50_Q41E86 Cluster: 2,5-didehydrogluconate reductase; n=2;
Bacteria|Rep: 2,5-didehydrogluconate reductase -
Exiguobacterium sibiricum 255-15
Length = 274
Score = 59.7 bits (138), Expect = 1e-07
Identities = 38/108 (35%), Positives = 58/108 (53%)
Frame = +3
Query: 357 GLKRESIFITTKLWNSYHEREQVIPALRKSLXKSQLGIRRPVFDSLAHSYV*ERYLARHV 536
G+ RE IF+TTK+WN E+ + A SL K LG+ V L H + + L
Sbjct: 62 GIPREDIFLTTKVWNKDQGYERTLAAFETSLQK--LGVDY-VDLYLIHWPMPDEDL---- 114
Query: 537 DFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGLEKPSALQIE 680
++DTWR + + G K+IG+SNF+ + R+++ G P+ QIE
Sbjct: 115 -YMDTWRALEQLYRDGKAKAIGVSNFHIPHLTRVLEEGTVVPAVNQIE 161
>UniRef50_Q16K66 Cluster: Aldo-keto reductase; n=2; Aedes
aegypti|Rep: Aldo-keto reductase - Aedes aegypti
(Yellowfever mosquito)
Length = 303
Score = 59.7 bits (138), Expect = 1e-07
Identities = 38/119 (31%), Positives = 61/119 (51%), Gaps = 8/119 (6%)
Frame = +3
Query: 348 FSEG--LKRESIFITTKLWNSYHEREQVIPALRKSLXKSQLG------IRRPVFDSLAHS 503
FS+G + RE +FI +KL ++H E V R SL + L + PV +
Sbjct: 60 FSQGNDINREDVFIVSKLGPTFHRPEAVEKGCRLSLERLGLDYVDLYLMHTPVAARDSGD 119
Query: 504 YV*ERYLARHVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGLEKPSALQIE 680
+ V L+TW+ + + ++ GL +SIG+SNFN+EQ+ I+ G +P Q+E
Sbjct: 120 GNDRSEIDDEVTPLETWKALEECQRKGLVRSIGVSNFNEEQLMEIVTHGSIRPVVNQVE 178
Score = 36.7 bits (81), Expect = 0.92
Identities = 25/66 (37%), Positives = 37/66 (56%)
Frame = +2
Query: 146 LQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQV 325
L L++G +IP + LGT+ K+ +D A+ A+E GY IDTA+ Y E V
Sbjct: 2 LALNNGHSIPPIGLGTY-------KITG--SDGVAAIKSAVEFGYRLIDTAFVYNNEQVV 52
Query: 326 GRALXQ 343
G+AL +
Sbjct: 53 GQALRE 58
>UniRef50_A5PDA8 Cluster: Putative oxidoreductase protein; n=1;
Erythrobacter sp. SD-21|Rep: Putative oxidoreductase
protein - Erythrobacter sp. SD-21
Length = 272
Score = 59.3 bits (137), Expect = 2e-07
Identities = 38/102 (37%), Positives = 55/102 (53%)
Frame = +3
Query: 375 IFITTKLWNSYHEREQVIPALRKSLXKSQLGIRRPVFDSLAHSYV*ERYLARHVDFLDTW 554
IF+ TK+WN ++ + A K L + LG R V L H E+ F+DTW
Sbjct: 67 IFLQTKIWNDSQGYDRTLRAAEKCLER--LG-REHVDMLLIHWPCPEKD-----QFVDTW 118
Query: 555 RGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGLEKPSALQIE 680
+ +I+ + G KSIG+SNF +E ++RIID P+ QIE
Sbjct: 119 KALIELRDAGKAKSIGVSNFREEDLKRIIDETGVTPALNQIE 160
Score = 42.3 bits (95), Expect = 0.018
Identities = 26/68 (38%), Positives = 33/68 (48%)
Frame = +2
Query: 140 PTLQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIED 319
PTL L+ G IP + GTW D QAV A++ GY IDTA YG E
Sbjct: 5 PTLNLNDGRQIPQLGFGTWQMEE---------EDAPQAVSTAIDVGYWLIDTAAIYGNEK 55
Query: 320 QVGRALXQ 343
VG+ + +
Sbjct: 56 GVGKGVGE 63
>UniRef50_Q2UGR1 Cluster: Aldo/keto reductase family proteins; n=2;
Ascomycota|Rep: Aldo/keto reductase family proteins -
Aspergillus oryzae
Length = 323
Score = 59.3 bits (137), Expect = 2e-07
Identities = 43/123 (34%), Positives = 66/123 (53%), Gaps = 15/123 (12%)
Frame = +3
Query: 357 GLKRESIFITTKLWNSYHEREQVIPALRKSLXKSQLG------IRRPV-FDSLAHSY--- 506
G+ R+ IFIT+KLWN++H E V A+ K+L Q I PV F+ +
Sbjct: 65 GVPRDQIFITSKLWNTHHHPEHVEEAVNKTLKDLQTDYLDLYLIHWPVAFEHTNETLTPI 124
Query: 507 --V*ERYLARHVDFLDTWRG---MIDAKKLGLTKSIGISNFNQEQIQRIIDSGLEKPSAL 671
V +R+ +V DTW +++AKK+ +SIGISNF Q++I ++ + P+
Sbjct: 125 DPVTKRFRLANVPIADTWAALEKLVEAKKI---RSIGISNFTQDKIDDLLKTAKIPPAVN 181
Query: 672 QIE 680
QIE
Sbjct: 182 QIE 184
Score = 49.6 bits (113), Expect = 1e-04
Identities = 29/62 (46%), Positives = 37/62 (59%)
Frame = +2
Query: 143 TLQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQ 322
T +L+SG NIP + LGTWL +P ++ E AV AL AGY HID A Y E++
Sbjct: 6 TFKLNSGYNIPAIGLGTWLS-KP--------HEVENAVEAALRAGYRHIDAAACYQNENE 56
Query: 323 VG 328
VG
Sbjct: 57 VG 58
>UniRef50_Q28P63 Cluster: Aldo/keto reductase; n=4;
Rhodobacteraceae|Rep: Aldo/keto reductase - Jannaschia
sp. (strain CCS1)
Length = 276
Score = 58.8 bits (136), Expect = 2e-07
Identities = 41/111 (36%), Positives = 58/111 (52%), Gaps = 1/111 (0%)
Frame = +3
Query: 351 SEGLKRESIFITTKLWNSYHEREQVIPALRKSLXKSQLGIRRPVFDS-LAHSYV*ERYLA 527
+ GL R+ +F+TTK+WN+ EQ R S+ +S I D L H V + L
Sbjct: 63 ASGLPRDEVFVTTKVWNN----EQGAAKARASVERSLKTIGVEQLDLVLIHWPVPSQDL- 117
Query: 528 RHVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGLEKPSALQIE 680
+L+TW+ D + GL +SIG SNFN + ++RII E P QIE
Sbjct: 118 ----YLETWKAFQDMRDEGLMRSIGTSNFNADHLERIIAETGEAPVLNQIE 164
>UniRef50_A6W8E7 Cluster: 2,5-didehydrogluconate reductase; n=3;
Actinomycetales|Rep: 2,5-didehydrogluconate reductase -
Kineococcus radiotolerans SRS30216
Length = 289
Score = 58.8 bits (136), Expect = 2e-07
Identities = 36/108 (33%), Positives = 58/108 (53%)
Frame = +3
Query: 357 GLKRESIFITTKLWNSYHEREQVIPALRKSLXKSQLGIRRPVFDSLAHSYV*ERYLARHV 536
G+ R+ I++T+KL N +HE + A RK++ S +R P+ L H + Y
Sbjct: 73 GVPRDEIWVTSKLNNGFHEPD----AARKAVDDSVEKLRGPIDLYLIHWPLPTLYGG--- 125
Query: 537 DFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGLEKPSALQIE 680
DF+ TW+ + +A+ G +SIG+SNF +QR+ P+ QIE
Sbjct: 126 DFVSTWKVLEEARAAGKLRSIGVSNFQVNHLQRLAQEATVVPAVNQIE 173
Score = 43.6 bits (98), Expect = 0.008
Identities = 28/70 (40%), Positives = 37/70 (52%), Gaps = 1/70 (1%)
Frame = +2
Query: 131 LIVPTLQLSSGGNIPVVALGTWLGHRPKGKVVQVT-NDTEQAVIYALEAGYTHIDTAYKY 307
+ VPT+ L+ G IP + G V Q+ DT QAV AL+ GY HIDTA Y
Sbjct: 10 MTVPTILLNDGREIPQLGFG----------VFQIEPGDTAQAVKTALDLGYRHIDTAQMY 59
Query: 308 GIEDQVGRAL 337
G E +V + +
Sbjct: 60 GNEAEVAQGI 69
>UniRef50_P15339 Cluster: 2,5-diketo-D-gluconic acid reductase B;
n=6; Actinomycetales|Rep: 2,5-diketo-D-gluconic acid
reductase B - Corynebacterium sp. (strain SHS752001)
Length = 277
Score = 58.8 bits (136), Expect = 2e-07
Identities = 36/110 (32%), Positives = 62/110 (56%)
Frame = +3
Query: 351 SEGLKRESIFITTKLWNSYHEREQVIPALRKSLXKSQLGIRRPVFDSLAHSYV*ERYLAR 530
+ + R+ + + +K+ H R + + ++R SL + LG+ V D L + + R
Sbjct: 63 ASSVDRDELIVASKIPGRQHGRAEAVDSIRGSLDR--LGL--DVID-LQLIHWPNPSVGR 117
Query: 531 HVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGLEKPSALQIE 680
+LDTWRGMIDA++ GL +SIG+SNF + ++ +ID P+ Q+E
Sbjct: 118 ---WLDTWRGMIDAREAGLVRSIGVSNFTEPMLKTLIDETGVTPAVNQVE 164
Score = 33.5 bits (73), Expect = 8.6
Identities = 21/67 (31%), Positives = 34/67 (50%)
Frame = +2
Query: 137 VPTLQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIE 316
+PT+ L+ G LGT+ +G A++ A+++GY +DTA Y E
Sbjct: 4 IPTISLNDGRPFAEPGLGTYNLRGDEGVA---------AMVAAIDSGYRLLDTAVNYENE 54
Query: 317 DQVGRAL 337
+VGRA+
Sbjct: 55 SEVGRAV 61
>UniRef50_Q7N0E4 Cluster: 2,5-diketo-D-gluconic acid reductase A;
n=2; Bacteria|Rep: 2,5-diketo-D-gluconic acid reductase
A - Photorhabdus luminescens subsp. laumondii
Length = 292
Score = 58.4 bits (135), Expect = 3e-07
Identities = 39/107 (36%), Positives = 54/107 (50%)
Frame = +3
Query: 360 LKRESIFITTKLWNSYHEREQVIPALRKSLXKSQLGIRRPVFDSLAHSYV*ERYLARHVD 539
+ RE IF+TTKLWN H + AL +SL K QL Y+
Sbjct: 66 IPREDIFVTTKLWNDRHLDARA--ALTESLEKLQL--------DYVDLYLIHWPAPPQDQ 115
Query: 540 FLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGLEKPSALQIE 680
++ W+ +I+ +K GL +SIG+SNF E IQR+I+ P QIE
Sbjct: 116 YVGAWQQLIELQKEGLIRSIGVSNFQPEHIQRLINETGVHPVINQIE 162
Score = 35.1 bits (77), Expect = 2.8
Identities = 25/73 (34%), Positives = 36/73 (49%)
Frame = +2
Query: 140 PTLQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIED 319
P ++L+ G ++P + LG+W Q +T A AL+ GY IDTA Y E
Sbjct: 5 PIIRLADGNHMPQLGLGSWASDD------QQIAETIHA---ALDIGYRAIDTAAIYNNEK 55
Query: 320 QVGRALXQEILRR 358
VG AL + + R
Sbjct: 56 GVGNALQETDIPR 68
Score = 34.3 bits (75), Expect = 4.9
Identities = 13/17 (76%), Positives = 14/17 (82%)
Frame = +1
Query: 448 LXNLNLEYVDLYLIHWP 498
L L L+YVDLYLIHWP
Sbjct: 93 LEKLQLDYVDLYLIHWP 109
>UniRef50_Q5K8C5 Cluster: Aldo-keto reductase, putative; n=1;
Filobasidiella neoformans|Rep: Aldo-keto reductase,
putative - Cryptococcus neoformans (Filobasidiella
neoformans)
Length = 303
Score = 58.4 bits (135), Expect = 3e-07
Identities = 40/109 (36%), Positives = 60/109 (55%), Gaps = 1/109 (0%)
Frame = +3
Query: 357 GLKRESIFITTKLWNSYHEREQVIPALRKSLXKSQLGIRRPVFDS-LAHSYV*ERYLARH 533
G RE IF+T+KL N+ EQ L+ SL +S G+ FD L HS + + ++
Sbjct: 95 GTSREEIFLTSKLKNN-SSYEQAFVDLKGSLKRS--GVE--YFDLYLMHSAIGGPVIRKN 149
Query: 534 VDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGLEKPSALQIE 680
V W+ + DA+ GL KSIG+SNF ++ IQ ID + P+ Q++
Sbjct: 150 V-----WKALCDAQSQGLVKSIGVSNFGKKHIQEFIDQKVPLPTVNQVD 193
Score = 34.3 bits (75), Expect = 4.9
Identities = 16/33 (48%), Positives = 21/33 (63%)
Frame = +2
Query: 239 DTEQAVIYALEAGYTHIDTAYKYGIEDQVGRAL 337
+T V +ALEAGY H+DTA Y E G+A+
Sbjct: 55 ETYDCVKWALEAGYRHVDTAEWYENEAPCGKAI 87
>UniRef50_A2R6Z3 Cluster: Catalytic activity: an alcohol + NADP(+)
<=> an aldehyde + NADPH; n=9; Pezizomycotina|Rep:
Catalytic activity: an alcohol + NADP(+) <=> an aldehyde
+ NADPH - Aspergillus niger
Length = 345
Score = 58.4 bits (135), Expect = 3e-07
Identities = 43/120 (35%), Positives = 62/120 (51%), Gaps = 12/120 (10%)
Frame = +3
Query: 357 GLKRESIFITTKLWNSYHEREQVIPALRKSLXKSQLG------IRRPV---FDSLAHSYV 509
G+ RE IF+T+KLWN++H E V A+ KSL Q I PV + + V
Sbjct: 65 GVPREEIFLTSKLWNTHHHPENVEEAVDKSLADLQTDYLDLYLIHWPVAFRYSTTTIQPV 124
Query: 510 *ERY-LARHVD--FLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGLEKPSALQIE 680
E+ L VD DTW M + G +SIG+SNF +E+I+ ++ + P+ QIE
Sbjct: 125 NEQTGLIDVVDVPIKDTWAAMEKLVEKGKVRSIGVSNFTREKIEELLKTAKITPAVNQIE 184
Score = 46.4 bits (105), Expect = 0.001
Identities = 25/62 (40%), Positives = 35/62 (56%)
Frame = +2
Query: 143 TLQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQ 322
T +L++G ++P V LGTW + ++ AVI AL+ GY HID A YG E +
Sbjct: 6 TFKLNTGYDMPAVGLGTWQSKK---------DEVRDAVIAALKCGYRHIDAAAVYGNEQE 56
Query: 323 VG 328
VG
Sbjct: 57 VG 58
Score = 34.7 bits (76), Expect = 3.7
Identities = 13/27 (48%), Positives = 19/27 (70%)
Frame = +1
Query: 448 LXNLNLEYVDLYLIHWPIAMFENDTLL 528
L +L +Y+DLYLIHWP+A + T +
Sbjct: 95 LADLQTDYLDLYLIHWPVAFRYSTTTI 121
>UniRef50_UPI000023D0F1 Cluster: hypothetical protein FG03517.1;
n=1; Gibberella zeae PH-1|Rep: hypothetical protein
FG03517.1 - Gibberella zeae PH-1
Length = 364
Score = 58.0 bits (134), Expect = 3e-07
Identities = 35/113 (30%), Positives = 62/113 (54%), Gaps = 3/113 (2%)
Frame = +3
Query: 351 SEGLKRESIFITTKLWNSYHEREQVIPALRKSLXKSQLGIRRPVFDSLAH--SYV*E-RY 521
+ G+ R+ I++T KLWN+ H E V A+ S+ + LG+ + + ++V E R
Sbjct: 108 ASGVSRDEIWVTGKLWNTDHRPELVRKAIETSI--ANLGVEYLDLYLIHYPVAWVPETRD 165
Query: 522 LARHVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGLEKPSALQIE 680
+ + +DTW+ M + + GLT++IG SNF + I +I+ +P A + E
Sbjct: 166 VDNNTSLIDTWKAMEELVRAGLTRNIGFSNFAPKDINKILKIASIQPYAHEFE 218
Score = 44.0 bits (99), Expect = 0.006
Identities = 27/57 (47%), Positives = 33/57 (57%)
Frame = +2
Query: 167 NIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQVGRAL 337
+IP LGTWL KG VV AV YAL+ GY HIDTA + ED+VG+ +
Sbjct: 59 DIPAFGLGTWLAG--KGVVVP-------AVEYALKGGYRHIDTALIWRNEDEVGKGI 106
>UniRef50_Q83N50 Cluster: 2,5-diketo-D-gluconic acid reductase; n=2;
Tropheryma whipplei|Rep: 2,5-diketo-D-gluconic acid
reductase - Tropheryma whipplei (strain Twist)
(Whipple's bacillus)
Length = 283
Score = 58.0 bits (134), Expect = 3e-07
Identities = 41/115 (35%), Positives = 61/115 (53%), Gaps = 5/115 (4%)
Frame = +3
Query: 351 SEGLKRESIFITTKLWNSYHEREQVIPALRKSLXKSQLGIRRPVFDSLAHSYV*ERYLAR 530
S G+KRE F+TTKLWNS +Q P R++ +S D L+ YV + YL
Sbjct: 68 SSGIKREEFFVTTKLWNS----DQ--PKPREAFERS--------LDLLSLDYV-DLYLIH 112
Query: 531 HVD-----FLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGLEKPSALQIE 680
+++ W +++ K+ G KS+G+SNF E I +I ++G PS QIE
Sbjct: 113 WPCPPSELYINVWEVLLELKESGRAKSVGVSNFLSEHIDKIKEAGFPLPSVNQIE 167
Score = 43.6 bits (98), Expect = 0.008
Identities = 28/74 (37%), Positives = 38/74 (51%)
Frame = +2
Query: 137 VPTLQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIE 316
VP++ L G +IP LGT+ P N+ V A+E GY HIDTA Y E
Sbjct: 9 VPSVLLGDGVSIPQFGLGTY--ELPP-------NEASSVVQSAIELGYRHIDTASLYANE 59
Query: 317 DQVGRALXQEILRR 358
+VGRA+ ++R
Sbjct: 60 REVGRAIASSGIKR 73
Score = 33.5 bits (73), Expect = 8.6
Identities = 12/14 (85%), Positives = 14/14 (100%)
Frame = +1
Query: 457 LNLEYVDLYLIHWP 498
L+L+YVDLYLIHWP
Sbjct: 101 LSLDYVDLYLIHWP 114
>UniRef50_Q5FK98 Cluster: Oxidoreductase; n=8; Lactobacillales|Rep:
Oxidoreductase - Lactobacillus acidophilus
Length = 285
Score = 58.0 bits (134), Expect = 3e-07
Identities = 31/72 (43%), Positives = 42/72 (58%)
Frame = +2
Query: 143 TLQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQ 322
T L++G IP++ GTW P G+V E++V+ AL GY HIDTA YG ED
Sbjct: 9 TYTLNNGVKIPIIGFGTW--QTPDGEVA------EESVLAALNCGYRHIDTASAYGNEDS 60
Query: 323 VGRALXQEILRR 358
VGRA+ + + R
Sbjct: 61 VGRAIQKSGINR 72
Score = 55.6 bits (128), Expect = 2e-06
Identities = 32/109 (29%), Positives = 57/109 (52%), Gaps = 2/109 (1%)
Frame = +3
Query: 357 GLKRESIFITTKLWNSYHEREQVIPALRKSLXKSQLGIRRPVFDSLAHSYV*ERYLARHV 536
G+ R +FITTKLWNS H E+ +K++ +S L ++ D + + H
Sbjct: 69 GINRHELFITTKLWNSDHGYEKT----KKAIDQSLLDLKLDYLDMYLIHWPNPSSMRDHW 124
Query: 537 DFL--DTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGLEKPSALQI 677
+ ++WR M +A + G ++IG+SNF + + ++++ KP QI
Sbjct: 125 AEINAESWRAMEEAVRAGKIRAIGVSNFRKHHLDALMETAEIKPVVNQI 173
>UniRef50_P38715 Cluster: NADPH-dependent aldose reductase GRE3;
n=39; cellular organisms|Rep: NADPH-dependent aldose
reductase GRE3 - Saccharomyces cerevisiae (Baker's
yeast)
Length = 327
Score = 58.0 bits (134), Expect = 3e-07
Identities = 47/134 (35%), Positives = 65/134 (48%), Gaps = 21/134 (15%)
Frame = +3
Query: 342 KKFSEGL-KRESIFITTKLWNSYHEREQVIPALRKSLXKSQLGIRRPVFDS--LAHSYV* 512
K SEGL R+ IF+ +KLWN++H + V AL+K+L L + +A YV
Sbjct: 61 KAISEGLVSRKDIFVVSKLWNNFHHPDHVKLALKKTLSDMGLDYLDLYYIHFPIAFKYVP 120
Query: 513 --ERY----------------LARHVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRI 638
E+Y HV +DT+R + + GL KSIG+SNF IQ +
Sbjct: 121 FEEKYPPGFYTGADDEKKGHITEAHVPIIDTYRALEECVDEGLIKSIGVSNFQGSLIQDL 180
Query: 639 IDSGLEKPSALQIE 680
+ KP ALQIE
Sbjct: 181 LRGCRIKPVALQIE 194
>UniRef50_P06632 Cluster: 2,5-diketo-D-gluconic acid reductase A;
n=8; Actinomycetales|Rep: 2,5-diketo-D-gluconic acid
reductase A - Corynebacterium sp. (strain ATCC 31090)
Length = 278
Score = 58.0 bits (134), Expect = 3e-07
Identities = 36/118 (30%), Positives = 58/118 (49%)
Frame = +3
Query: 327 EGPXTKKFSEGLKRESIFITTKLWNSYHEREQVIPALRKSLXKSQLGIRRPVFDSLAHSY 506
EG + G+ R+ +FITTKLWN H+ ++ A+ +SL K L Y
Sbjct: 54 EGVGAAIAASGIARDDLFITTKLWNDRHDGDEPAAAIAESLAKLAL--------DQVDLY 105
Query: 507 V*ERYLARHVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGLEKPSALQIE 680
+ +++ W MI+ + GLT+SIG+SN ++RI+ + P+ QIE
Sbjct: 106 LVHWPTPAADNYVHAWEKMIELRAAGLTRSIGVSNHLVPHLERIVAATGVVPAVNQIE 163
Score = 46.4 bits (105), Expect = 0.001
Identities = 29/69 (42%), Positives = 40/69 (57%)
Frame = +2
Query: 131 LIVPTLQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYG 310
+ VP++ L+ G +IP + G + KV DT++AV ALE GY HIDTA YG
Sbjct: 1 MTVPSIVLNDGNSIPQLGYGVF-------KVPPA--DTQRAVEEALEVGYRHIDTAAIYG 51
Query: 311 IEDQVGRAL 337
E+ VG A+
Sbjct: 52 NEEGVGAAI 60
>UniRef50_Q96UH3 Cluster: Aldehyde reductase; n=13;
Pezizomycotina|Rep: Aldehyde reductase - Coccidioides
posadasii
Length = 314
Score = 57.6 bits (133), Expect = 5e-07
Identities = 36/117 (30%), Positives = 63/117 (53%), Gaps = 10/117 (8%)
Frame = +3
Query: 360 LKRESIFITTKLWNSYHEREQVIPALRKSLXKSQLG------IRRPVF----DSLAHSYV 509
L R+ +FIT+KLWN+ H E V A+ +SL ++ + P D +
Sbjct: 66 LSRDELFITSKLWNNKHRPEDVEQAIDQSLKNLEIDYLDLYLMHWPAAFAPGDDMFPKDS 125
Query: 510 *ERYLARHVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGLEKPSALQIE 680
+D++DT++ M K G TK+IGISNF++ +++R+++S P+ +Q+E
Sbjct: 126 QGNSKTVDIDYVDTYKAMEKLVKSGKTKAIGISNFSKGEMERLLESCSIVPAVMQME 182
Score = 56.4 bits (130), Expect = 1e-06
Identities = 32/72 (44%), Positives = 40/72 (55%)
Frame = +2
Query: 143 TLQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQ 322
T +L++G +IP + GTW Q N E AV+ AL AGY HIDTA YG E
Sbjct: 7 TFRLNTGEDIPAIGFGTW----------QDENAQEDAVLTALSAGYRHIDTAAVYGTEKA 56
Query: 323 VGRALXQEILRR 358
+GRAL + L R
Sbjct: 57 IGRALARSRLSR 68
Score = 36.3 bits (80), Expect = 1.2
Identities = 13/26 (50%), Positives = 18/26 (69%)
Frame = +1
Query: 448 LXNLNLEYVDLYLIHWPIAMFENDTL 525
L NL ++Y+DLYL+HWP A D +
Sbjct: 95 LKNLEIDYLDLYLMHWPAAFAPGDDM 120
>UniRef50_P15121 Cluster: Aldose reductase; n=72; Eumetazoa|Rep:
Aldose reductase - Homo sapiens (Human)
Length = 316
Score = 57.6 bits (133), Expect = 5e-07
Identities = 43/119 (36%), Positives = 63/119 (52%), Gaps = 12/119 (10%)
Frame = +3
Query: 360 LKRESIFITTKLWNSYHEREQVIPALRKSLXKSQLG------IRRPV-FDSLAHSYV*ER 518
+KRE +FI +KLW +YHE+ V A +K+L +L I P F + +
Sbjct: 68 VKREELFIVSKLWCTYHEKGLVKGACQKTLSDLKLDYLDLYLIHWPTGFKPGKEFFPLDE 127
Query: 519 ---YLARHVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDS-GLE-KPSALQIE 680
+ + LDTW M + GL K+IGISNFN Q++ I++ GL+ KP+ QIE
Sbjct: 128 SGNVVPSDTNILDTWAAMEELVDEGLVKAIGISNFNHLQVEMILNKPGLKYKPAVNQIE 186
Score = 49.2 bits (112), Expect = 2e-04
Identities = 28/79 (35%), Positives = 46/79 (58%)
Frame = +2
Query: 146 LQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQV 325
L L++G +P++ LGTW P G+V + AV A++ GY HID A+ Y E++V
Sbjct: 5 LLLNNGAKMPILGLGTWKS--PPGQVTE-------AVKVAIDVGYRHIDCAHVYQNENEV 55
Query: 326 GRALXQEILRRT*KRIYLY 382
G A+ +++ + KR L+
Sbjct: 56 GVAIQEKLREQVVKREELF 74
Score = 33.5 bits (73), Expect = 8.6
Identities = 12/17 (70%), Positives = 15/17 (88%)
Frame = +1
Query: 448 LXNLNLEYVDLYLIHWP 498
L +L L+Y+DLYLIHWP
Sbjct: 97 LSDLKLDYLDLYLIHWP 113
>UniRef50_P51857 Cluster: 3-oxo-5-beta-steroid 4-dehydrogenase (EC
1.3.1.3) (Delta(4)-3- ketosteroid 5-beta-reductase);
n=124; cellular organisms|Rep: 3-oxo-5-beta-steroid
4-dehydrogenase (EC 1.3.1.3) (Delta(4)-3- ketosteroid
5-beta-reductase) - Homo sapiens (Human)
Length = 326
Score = 57.2 bits (132), Expect = 6e-07
Identities = 43/126 (34%), Positives = 65/126 (51%), Gaps = 13/126 (10%)
Frame = +3
Query: 342 KKFSEG-LKRESIFITTKLWNSYHEREQVIPALRKSLXKSQLG------IRRPVF----D 488
+K +EG ++RE IF KLW + H E V P L ++L QL I P+ D
Sbjct: 70 EKIAEGKVRREDIFYCGKLWATNHVPEMVRPTLERTLRVLQLDYVDLYIIEVPMAFKPGD 129
Query: 489 SLAHSYV*ERYLARHVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDS-GLE-KP 662
+ ++L + TW M K GL KS+G+SNFN+ Q++ I++ GL+ KP
Sbjct: 130 EIYPRDENGKWLYHKSNLCATWEAMEACKDAGLVKSLGVSNFNRRQLELILNKPGLKHKP 189
Query: 663 SALQIE 680
+ Q+E
Sbjct: 190 VSNQVE 195
Score = 45.2 bits (102), Expect = 0.003
Identities = 25/68 (36%), Positives = 38/68 (55%)
Frame = +2
Query: 146 LQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQV 325
+ LS G +IP++ LGT+ + K T+ V A++ GY HID AY Y E +V
Sbjct: 10 IPLSDGNSIPIIGLGTYSEPKSTPKGACATS-----VKVAIDTGYRHIDGAYIYQNEHEV 64
Query: 326 GRALXQEI 349
G A+ ++I
Sbjct: 65 GEAIREKI 72
>UniRef50_Q01J82 Cluster: OSIGBa0152K17.5 protein; n=28;
Magnoliophyta|Rep: OSIGBa0152K17.5 protein - Oryza
sativa (Rice)
Length = 323
Score = 56.4 bits (130), Expect = 1e-06
Identities = 35/112 (31%), Positives = 57/112 (50%), Gaps = 7/112 (6%)
Frame = +3
Query: 366 RESIFITTKLWNSYHEREQVIPALRKSLXKSQLG------IRRPVFDSLAHSYV*-ERYL 524
RE +F+TTKLW + V+P+LR+SL Q+ + P+ + +R
Sbjct: 78 REEVFVTTKLWCTQCHPGLVLPSLRESLRNLQMEYVDLYLVHWPISVKPGPPMLPVKRED 137
Query: 525 ARHVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGLEKPSALQIE 680
A DF WR M + +LGL K+IG+SNF + + +++ P+ Q+E
Sbjct: 138 AVPFDFEGVWRAMEECHRLGLAKAIGVSNFTTKHLDKLLAVATIPPAVNQVE 189
Score = 39.1 bits (87), Expect = 0.17
Identities = 14/20 (70%), Positives = 18/20 (90%)
Frame = +1
Query: 448 LXNLNLEYVDLYLIHWPIAM 507
L NL +EYVDLYL+HWPI++
Sbjct: 105 LRNLQMEYVDLYLVHWPISV 124
Score = 35.9 bits (79), Expect = 1.6
Identities = 24/73 (32%), Positives = 33/73 (45%)
Frame = +2
Query: 137 VPTLQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIE 316
VP + L G P+ A+G +G T A + ALE G+ H DTA YG E
Sbjct: 4 VPEVALRHGAGRPMPAVG--VGTADSAATSPETK--RGAALAALEVGFRHFDTAALYGTE 59
Query: 317 DQVGRALXQEILR 355
+G A+ + R
Sbjct: 60 APLGEAIAEATRR 72
>UniRef50_A7P424 Cluster: Chromosome chr1 scaffold_5, whole genome
shotgun sequence; n=1; Vitis vinifera|Rep: Chromosome
chr1 scaffold_5, whole genome shotgun sequence - Vitis
vinifera (Grape)
Length = 247
Score = 56.0 bits (129), Expect = 1e-06
Identities = 35/110 (31%), Positives = 61/110 (55%), Gaps = 6/110 (5%)
Frame = +3
Query: 366 RESIFITTKLWNSYHEREQVIPALRKSLXKSQLGIRRPVFDSLAHSYV*ERYLAR----H 533
R+ +FIT+KLW S ++V+PAL+ +L S + +L Y+ + YL H
Sbjct: 77 RDELFITSKLWCSDAHHDRVLPALQNTLKISSI---LSFSKNLQLDYL-DLYLIHWSDGH 132
Query: 534 --VDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGLEKPSALQI 677
+D W+ M D +KL LTK+IG+SNF+ +++ ++ + P+ Q+
Sbjct: 133 LPIDLGSVWKAMEDFQKLSLTKAIGVSNFSCNKLEELLQTASILPAVNQV 182
>UniRef50_Q968S3 Cluster: Aldoketoreductase-like protein; n=1;
Orconectes limosus|Rep: Aldoketoreductase-like protein -
Orconectes limosus (Spinycheek crayfish)
Length = 336
Score = 55.6 bits (128), Expect = 2e-06
Identities = 47/124 (37%), Positives = 60/124 (48%), Gaps = 14/124 (11%)
Frame = +3
Query: 351 SEG-LKRESIFITTKLWNSYHEREQVIPALRKSLXKSQLGIRRPVFDSLAHSYV*----- 512
SEG +KRE +FITTKL + + V L+KSL +R P D Y
Sbjct: 79 SEGKVKREELFITTKLPTRGNREKDVARFLQKSLDN----LRLPYVDLYLVHYPCGILDT 134
Query: 513 --ERYLARHV------DFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGLEKPSA 668
ER A V D WR M G TK+IG+SNFN +Q+QRII +P+
Sbjct: 135 DRERLSADEVTVDPTTDIHAIWRAMEAQLAAGKTKNIGLSNFNADQVQRIIKGCQVRPAV 194
Query: 669 LQIE 680
LQ+E
Sbjct: 195 LQVE 198
Score = 49.2 bits (112), Expect = 2e-04
Identities = 34/83 (40%), Positives = 44/83 (53%), Gaps = 1/83 (1%)
Frame = +2
Query: 137 VPTLQLSSGGNIPVVALGTW-LGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGI 313
+PT+ L+SG +IPV+ LGT LG K VT E A LE GY H D+A YG
Sbjct: 11 IPTILLNSGSHIPVMGLGTGSLGRNGKMSEEAVTAVLETA----LECGYRHFDSAAYYGN 66
Query: 314 EDQVGRALXQEILRRT*KRIYLY 382
E +G+ L + I KR L+
Sbjct: 67 EAIIGQVLRRWISEGKVKREELF 89
Score = 34.7 bits (76), Expect = 3.7
Identities = 13/24 (54%), Positives = 17/24 (70%)
Frame = +1
Query: 448 LXNLNLEYVDLYLIHWPIAMFEND 519
L NL L YVDLYL+H+P + + D
Sbjct: 112 LDNLRLPYVDLYLVHYPCGILDTD 135
>UniRef50_Q7QVQ9 Cluster: GLP_302_44328_45269; n=1; Giardia lamblia
ATCC 50803|Rep: GLP_302_44328_45269 - Giardia lamblia
ATCC 50803
Length = 313
Score = 55.6 bits (128), Expect = 2e-06
Identities = 43/141 (30%), Positives = 63/141 (44%), Gaps = 13/141 (9%)
Frame = +3
Query: 297 HTNMESRTKWEGPXTKKFSEGLKRESIFITTKLWNSYHEREQVIPALRKSLXKSQLG--- 467
+ N E+ + G K S G+KRE ++IT+KLWN H E V +K++ Q+
Sbjct: 40 YQNEEAIGRAFGKIFKDASSGIKREDVWITSKLWNYNHRPELVREQCKKTMSDLQVDYLD 99
Query: 468 ----------IRRPVFDSLAHSYV*ERYLARHVDFLDTWRGMIDAKKLGLTKSIGISNFN 617
+R V D L R + V DTWR M + GL K IG+SN+
Sbjct: 100 LFLVHWPLAFVRNDVGD-LFPKDAEGRAMLEKVPLADTWRAMEQLVEEGLVKHIGVSNYT 158
Query: 618 QEQIQRIIDSGLEKPSALQIE 680
+ +++ KP QIE
Sbjct: 159 VPLLADLLNYAKIKPLVNQIE 179
Score = 36.3 bits (80), Expect = 1.2
Identities = 11/24 (45%), Positives = 19/24 (79%)
Frame = +1
Query: 448 LXNLNLEYVDLYLIHWPIAMFEND 519
+ +L ++Y+DL+L+HWP+A ND
Sbjct: 90 MSDLQVDYLDLFLVHWPLAFVRND 113
Score = 33.9 bits (74), Expect = 6.5
Identities = 16/30 (53%), Positives = 19/30 (63%)
Frame = +2
Query: 245 EQAVIYALEAGYTHIDTAYKYGIEDQVGRA 334
+ AV AL GY HID AY Y E+ +GRA
Sbjct: 20 QTAVETALMTGYRHIDCAYVYQNEEAIGRA 49
>UniRef50_Q8CI22 Cluster: 2310005E10Rik protein; n=30;
Tetrapoda|Rep: 2310005E10Rik protein - Mus musculus
(Mouse)
Length = 316
Score = 55.2 bits (127), Expect = 2e-06
Identities = 38/121 (31%), Positives = 63/121 (52%), Gaps = 12/121 (9%)
Frame = +3
Query: 354 EGLKRESIFITTKLWNSYHEREQVIPALRKSLXKSQLG------IRRPVFDSLAHSYV*E 515
+ +KRE +FI +KLW+++ E+ V A + +L +L I P + ++
Sbjct: 66 KAVKREDLFIVSKLWSTFFEKSLVKKAFQNTLSDLKLDYLDLYLIHWPQGFQSGNVFLPT 125
Query: 516 ----RYLARHVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDS-GLE-KPSALQI 677
L+ FLD W M + GL K++G+SNFN QI+R+++ GL+ KP Q+
Sbjct: 126 DDKGSILSSKYTFLDAWEAMEELVDQGLVKALGVSNFNHFQIERLLNKPGLKHKPVTNQV 185
Query: 678 E 680
E
Sbjct: 186 E 186
Score = 52.8 bits (121), Expect = 1e-05
Identities = 31/77 (40%), Positives = 43/77 (55%)
Frame = +2
Query: 152 LSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQVGR 331
L +G +P+V LGTW P KV +AV A++AGY HID AY Y E +VG
Sbjct: 7 LLTGAKMPIVGLGTWKS--PPAKV-------REAVKVAIDAGYRHIDCAYVYQNESEVGE 57
Query: 332 ALXQEILRRT*KRIYLY 382
A+ ++I + KR L+
Sbjct: 58 AIQEKIQEKAVKREDLF 74
Score = 34.7 bits (76), Expect = 3.7
Identities = 14/29 (48%), Positives = 18/29 (62%)
Frame = +1
Query: 448 LXNLNLEYVDLYLIHWPIAMFENDTLLDT 534
L +L L+Y+DLYLIHWP + L T
Sbjct: 97 LSDLKLDYLDLYLIHWPQGFQSGNVFLPT 125
>UniRef50_Q927E1 Cluster: Lin2848 protein; n=13; Listeria|Rep:
Lin2848 protein - Listeria innocua
Length = 280
Score = 55.2 bits (127), Expect = 2e-06
Identities = 36/110 (32%), Positives = 52/110 (47%)
Frame = +3
Query: 351 SEGLKRESIFITTKLWNSYHEREQVIPALRKSLXKSQLGIRRPVFDSLAHSYV*ERYLAR 530
S GLKR+ F+TTK+WN+ ++ + A KS K QL V L H +
Sbjct: 66 SSGLKRDEFFVTTKMWNTEQGYDETLRAFEKSQKKLQLD---QVDLYLVH-------WPK 115
Query: 531 HVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGLEKPSALQIE 680
F +TWR + GL ++IG+SNF + R+ S P Q+E
Sbjct: 116 QDTFFETWRAVEKLYDEGLVRAIGVSNFEAHHLDRLRTSANVLPVVDQLE 165
>UniRef50_Q41399 Cluster: Chalcone reductase; n=4;
eudicotyledons|Rep: Chalcone reductase - Sesbania
rostrata
Length = 322
Score = 55.2 bits (127), Expect = 2e-06
Identities = 35/124 (28%), Positives = 63/124 (50%), Gaps = 10/124 (8%)
Frame = +3
Query: 339 TKKFSEGL--KRESIFITTKLWNSYHEREQVIPALRKSLXKSQLG------IRRPVF--D 488
+K +GL R+ +FIT+K WN+ + ++PAL+ +L K + I PV
Sbjct: 67 SKAIEQGLIKSRDEVFITSKPWNTDAHHDLIVPALKTTLKKLGMEYVDLYLIHWPVRLRH 126
Query: 489 SLAHSYV*ERYLARHVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGLEKPSA 668
L + + + D TW+ M + +LGL KSIGI N+ +++ ++++ P+
Sbjct: 127 DLENPVIFSKEDLLPFDIEGTWKAMEECYRLGLAKSIGICNYGTKKLTKLLEIATIPPAV 186
Query: 669 LQIE 680
Q+E
Sbjct: 187 NQVE 190
Score = 46.8 bits (106), Expect = 9e-04
Identities = 24/75 (32%), Positives = 41/75 (54%)
Frame = +2
Query: 125 ADLIVPTLQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYK 304
A+ +P + L+SG +PV+ +GT + RP V+ + A++ GY H D+A
Sbjct: 2 AEKKIPEVLLNSGHKMPVIGMGTSVESRPSNDVLA------SIFVDAIQVGYRHFDSASV 55
Query: 305 YGIEDQVGRALXQEI 349
YG E+ +G A+ + I
Sbjct: 56 YGTEEAIGMAVSKAI 70
Score = 36.3 bits (80), Expect = 1.2
Identities = 13/20 (65%), Positives = 16/20 (80%)
Frame = +1
Query: 448 LXNLNLEYVDLYLIHWPIAM 507
L L +EYVDLYLIHWP+ +
Sbjct: 105 LKKLGMEYVDLYLIHWPVRL 124
>UniRef50_UPI00015B40FA Cluster: PREDICTED: similar to CG2767-PA;
n=2; Nasonia vitripennis|Rep: PREDICTED: similar to
CG2767-PA - Nasonia vitripennis
Length = 356
Score = 54.8 bits (126), Expect = 3e-06
Identities = 29/65 (44%), Positives = 41/65 (63%)
Frame = +2
Query: 143 TLQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQ 322
T++LSSG ++P++ LGTW P + E AV ALE+GY HIDTA+ YG E+
Sbjct: 27 TIKLSSGHDMPMIGLGTW--QMPPEAI-------EVAVTAALESGYRHIDTAFTYGNEEA 77
Query: 323 VGRAL 337
+G+ L
Sbjct: 78 IGKTL 82
Score = 54.0 bits (124), Expect = 6e-06
Identities = 43/126 (34%), Positives = 57/126 (45%), Gaps = 13/126 (10%)
Frame = +3
Query: 342 KKFSEGLKRESIFITTKLWNSYHEREQVIPALRKSLXKSQLGIRRPVFDSLAHSYV*ERY 521
K F +G KRE +FITTKL E V L+ SL K L ++V ++Y
Sbjct: 84 KWFDKGGKREDLFITTKLPPIGMRAEYVESYLKLSLEKLGLEYVNMYLIHKPFAFVKDKY 143
Query: 522 -------------LARHVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGLEKP 662
L D + WR M K G +SIG+SNFN+ Q+ + + KP
Sbjct: 144 KYEPALNPDGSVVLDTDTDHVAIWRAMEKQVKAGRVRSIGLSNFNKSQLLNVYEHAEIKP 203
Query: 663 SALQIE 680
S LQIE
Sbjct: 204 SNLQIE 209
>UniRef50_Q88SL1 Cluster: Oxidoreductase; n=51; Lactobacillales|Rep:
Oxidoreductase - Lactobacillus plantarum
Length = 286
Score = 54.8 bits (126), Expect = 3e-06
Identities = 30/73 (41%), Positives = 42/73 (57%)
Frame = +2
Query: 119 TSADLIVPTLQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTA 298
T+ + T L++G IP+V GTW P G+V +V+ AL+AGY HIDTA
Sbjct: 2 TALTKLTDTYTLNNGTKIPIVGFGTW--QTPDGQVAY------DSVLAALKAGYRHIDTA 53
Query: 299 YKYGIEDQVGRAL 337
YG E+ VG+A+
Sbjct: 54 AAYGNEESVGKAI 66
Score = 48.8 bits (111), Expect = 2e-04
Identities = 34/109 (31%), Positives = 54/109 (49%), Gaps = 2/109 (1%)
Frame = +3
Query: 357 GLKRESIFITTKLWNSYHEREQVIPALRKSLXKSQLGIRRPVFDSLAHSYV*ERYLARHV 536
G+ RE +F+TTKLWN+ H + AL SL K LG+ D + + +
Sbjct: 70 GVAREDLFVTTKLWNADHGYDAAKKALDTSLAK--LGL--DYVDLYLIHWPNPAAMRDNW 125
Query: 537 DFL--DTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGLEKPSALQI 677
+ L DTWR M +A ++IG+SNF + + ++ + P+ QI
Sbjct: 126 EQLNADTWRAMEEAYTARKARAIGVSNFRPKHLDALLKTAKVVPAVNQI 174
Score = 36.7 bits (81), Expect = 0.92
Identities = 20/34 (58%), Positives = 22/34 (64%), Gaps = 4/34 (11%)
Frame = +1
Query: 448 LXNLNLEYVDLYLIHW--PIAMFENDTLL--DTW 537
L L L+YVDLYLIHW P AM +N L DTW
Sbjct: 100 LAKLGLDYVDLYLIHWPNPAAMRDNWEQLNADTW 133
>UniRef50_Q5FKI1 Cluster: Reductase-dehydrogenase; n=1;
Lactobacillus acidophilus|Rep: Reductase-dehydrogenase -
Lactobacillus acidophilus
Length = 271
Score = 54.8 bits (126), Expect = 3e-06
Identities = 37/113 (32%), Positives = 58/113 (51%), Gaps = 2/113 (1%)
Frame = +3
Query: 348 FSEGLKRESIFITTKLWNSYHEREQVIPALRKSLXKSQLGIRRPVFDSLAHSYV*-ERYL 524
++ ++R IF+TTKL + + E A+ +L K L + ++ R
Sbjct: 62 WNSDIERSDIFLTTKLPTAVKDYEGTKKAIDAALDKFGLEYIDLLLIHSPQPWIEVNRTN 121
Query: 525 ARHVDF-LDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGLEKPSALQIE 680
RH L+ WR M +A K G +SIG+SNF QE I+ I+++G P+ QIE
Sbjct: 122 DRHFKGNLENWRAMEEAVKAGKVRSIGVSNFLQEDIENIVNNGTITPAVNQIE 174
Score = 38.3 bits (85), Expect = 0.30
Identities = 24/71 (33%), Positives = 34/71 (47%), Gaps = 1/71 (1%)
Frame = +2
Query: 152 LSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVI-YALEAGYTHIDTAYKYGIEDQVG 328
L++G IP + LGTWL + ND V+ A+ GY DTA YG E VG
Sbjct: 9 LNNGEKIPQIQLGTWL----------INNDEVNKVVRQAVNIGYRGFDTAKDYGNESGVG 58
Query: 329 RALXQEILRRT 361
+ + + R+
Sbjct: 59 KGIWNSDIERS 69
>UniRef50_Q8J0K1 Cluster: 4-dihydromethyltrisporate dehydrogenase;
n=2; Parasitella parasitica|Rep:
4-dihydromethyltrisporate dehydrogenase - Parasitella
parasitica
Length = 321
Score = 54.8 bits (126), Expect = 3e-06
Identities = 45/131 (34%), Positives = 64/131 (48%), Gaps = 18/131 (13%)
Frame = +3
Query: 342 KKFSEGL-KRESIFITTKLWNSYHEREQVIPALRKSLXKSQLG------IRRPV---FDS 491
K EGL KRE +FI TKLWN++H ++ V A + L L I P+ +
Sbjct: 63 KAIKEGLVKREELFIVTKLWNTFHSKQHVRTAFDRQLKDWGLEYFDLYLIHFPIPLQYVD 122
Query: 492 LAHSYV*ERYLARHVDFL--------DTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDS 647
A SY E Y+ H D L + W M + LT++IG++NFN + I ++
Sbjct: 123 PAVSYPPEWYVP-HADKLNFERSPIHECWAEMEKLVQAKLTRNIGVANFNCQAILDLLSY 181
Query: 648 GLEKPSALQIE 680
KP+ LQIE
Sbjct: 182 AKIKPAVLQIE 192
>UniRef50_Q7G765 Cluster: Probable NAD(P)H-dependent oxidoreductase
2; n=6; Magnoliophyta|Rep: Probable NAD(P)H-dependent
oxidoreductase 2 - Oryza sativa subsp. japonica (Rice)
Length = 322
Score = 54.8 bits (126), Expect = 3e-06
Identities = 34/114 (29%), Positives = 62/114 (54%), Gaps = 9/114 (7%)
Frame = +3
Query: 366 RESIFITTKLWNSYHEREQVIPALRKSLXK------SQLGIRRPVFDSLAHSY---V*ER 518
R +F+T+KLW S +V+PA R++L L + P + SY +
Sbjct: 79 RADVFVTSKLWCSDLHAGRVVPAARETLRNLGMDYVDLLLVHWPATVAPG-SYDFPFPKE 137
Query: 519 YLARHVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGLEKPSALQIE 680
+A D WRGM + +LGL ++IG+SNF+ +++++++ + +P+A Q+E
Sbjct: 138 EMAPAFDMEGVWRGMEECHRLGLARAIGVSNFSAKKLEQLLSFAVVRPAANQVE 191
Score = 33.9 bits (74), Expect = 6.5
Identities = 15/41 (36%), Positives = 23/41 (56%)
Frame = +2
Query: 233 TNDTEQAVIYALEAGYTHIDTAYKYGIEDQVGRALXQEILR 355
+ +T A++ A+E GY H DTA Y E V A+ + + R
Sbjct: 33 SEETTAALLRAIELGYRHFDTARLYATEGCVSEAVAEAVRR 73
>UniRef50_P47137 Cluster: Probable oxidoreductase YJR096W; n=8;
Saccharomycetales|Rep: Probable oxidoreductase YJR096W -
Saccharomyces cerevisiae (Baker's yeast)
Length = 282
Score = 54.4 bits (125), Expect = 4e-06
Identities = 40/108 (37%), Positives = 59/108 (54%), Gaps = 2/108 (1%)
Frame = +3
Query: 363 KRESIFITTKLWNSYHEREQVIPALRKSLXKSQLGIRRPVFDSLAHSYV*ERYLARHVDF 542
KRE IF TTKLWNS + ++ A+R+ L + G++ + L HS + L
Sbjct: 72 KREEIFYTTKLWNSQNGYKRAKAAIRQCLNEVS-GLQY-IDLLLIHSPLEGSKLR----- 124
Query: 543 LDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIID--SGLEKPSALQIE 680
L+TWR M +A GL KSIG+SN+ ++ I +++ KP QIE
Sbjct: 125 LETWRAMQEAVDEGLVKSIGVSNYGKKHIDELLNWPELKHKPVVNQIE 172
Score = 37.1 bits (82), Expect = 0.70
Identities = 22/60 (36%), Positives = 33/60 (55%)
Frame = +2
Query: 149 QLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQVG 328
+LS+G IP +ALGT+ P+ + ++ V ++ GY H DTA YG E +VG
Sbjct: 7 KLSNGFKIPSIALGTY--DIPRSQTAEI-------VYEGVKCGYRHFDTAVLYGNEKEVG 57
>UniRef50_Q8ZI40 Cluster: 2,5-diketo-D-gluconic acid reductase A;
n=74; Bacteria|Rep: 2,5-diketo-D-gluconic acid reductase
A - Yersinia pestis
Length = 277
Score = 54.4 bits (125), Expect = 4e-06
Identities = 38/118 (32%), Positives = 55/118 (46%)
Frame = +3
Query: 327 EGPXTKKFSEGLKRESIFITTKLWNSYHEREQVIPALRKSLXKSQLGIRRPVFDSLAHSY 506
EG + + R+ +FITTKLWN Q AL SL K QL Y
Sbjct: 55 EGVGKALKAAAVARDELFITTKLWNDDQHNPQ--QALETSLQKLQL--------DYVDLY 104
Query: 507 V*ERYLARHVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGLEKPSALQIE 680
+ + ++ WR ++ K+ GL +SIG+ NF+ +QR+ID P+ QIE
Sbjct: 105 LIHWPDPKQDHYVSAWRELVTLKEQGLIRSIGVCNFHIPHLQRLIDETGIAPTVNQIE 162
Score = 39.9 bits (89), Expect = 0.099
Identities = 27/73 (36%), Positives = 35/73 (47%)
Frame = +2
Query: 140 PTLQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIED 319
P ++L G +P + LG W +TE AV ALE GY IDTA Y E+
Sbjct: 5 PLIKLYDGRLMPQLGLGVWQAS---------IQETELAVSKALEVGYRSIDTAAIYKNEE 55
Query: 320 QVGRALXQEILRR 358
VG+AL + R
Sbjct: 56 GVGKALKAAAVAR 68
Score = 34.3 bits (75), Expect = 4.9
Identities = 13/17 (76%), Positives = 14/17 (82%)
Frame = +1
Query: 448 LXNLNLEYVDLYLIHWP 498
L L L+YVDLYLIHWP
Sbjct: 93 LQKLQLDYVDLYLIHWP 109
>UniRef50_UPI0000D56CE5 Cluster: PREDICTED: similar to CG6084-PA,
isoform A; n=1; Tribolium castaneum|Rep: PREDICTED:
similar to CG6084-PA, isoform A - Tribolium castaneum
Length = 493
Score = 54.0 bits (124), Expect = 6e-06
Identities = 26/54 (48%), Positives = 33/54 (61%)
Frame = +3
Query: 519 YLARHVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGLEKPSALQIE 680
++ VDF+DTW+ M + LTKSIGISNFN QI R++ S P QIE
Sbjct: 308 FIPSDVDFVDTWKAMEKMHEKDLTKSIGISNFNSNQIDRLLKSAKIAPVINQIE 361
Score = 42.7 bits (96), Expect = 0.014
Identities = 18/48 (37%), Positives = 31/48 (64%)
Frame = +3
Query: 537 DFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGLEKPSALQIE 680
+ ++TW M LT++IG+SNFN +QI+RI+++ +P QI+
Sbjct: 122 NLIETWEAMEGLYSEKLTRAIGLSNFNSKQIERILENCTIRPQVNQIQ 169
Score = 36.7 bits (81), Expect = 0.92
Identities = 14/26 (53%), Positives = 20/26 (76%)
Frame = +1
Query: 448 LXNLNLEYVDLYLIHWPIAMFENDTL 525
L NL L+Y+D+YL+HWP A+ E +L
Sbjct: 273 LKNLQLDYLDVYLMHWPHALKEGPSL 298
>UniRef50_Q1VRG6 Cluster: YvgN; n=1; Psychroflexus torquis ATCC
700755|Rep: YvgN - Psychroflexus torquis ATCC 700755
Length = 280
Score = 54.0 bits (124), Expect = 6e-06
Identities = 36/110 (32%), Positives = 51/110 (46%)
Frame = +3
Query: 351 SEGLKRESIFITTKLWNSYHEREQVIPALRKSLXKSQLGIRRPVFDSLAHSYV*ERYLAR 530
+ G+ RE IF+TTKLW +Q AL +SL K L + + Y
Sbjct: 60 ARGVLREEIFVTTKLWRENLGYKQTRIALDESLRKLDLNYIDLYLIHWPANAI--NYKDW 117
Query: 531 HVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGLEKPSALQIE 680
DTWR M + + G KS+G+SNF E ++ + + PS QIE
Sbjct: 118 QKTNADTWRAMEELQAEGKIKSLGVSNFWPEHLEALFQTAKVSPSVNQIE 167
>UniRef50_A1UEC5 Cluster: 2,5-didehydrogluconate reductase; n=20;
Corynebacterineae|Rep: 2,5-didehydrogluconate reductase
- Mycobacterium sp. (strain KMS)
Length = 283
Score = 54.0 bits (124), Expect = 6e-06
Identities = 36/110 (32%), Positives = 55/110 (50%)
Frame = +3
Query: 351 SEGLKRESIFITTKLWNSYHEREQVIPALRKSLXKSQLGIRRPVFDSLAHSYV*ERYLAR 530
+ G+ RE I++TTKL + A R SL + LG+ Y+
Sbjct: 70 ASGIPREEIYVTTKLAVADQGFGTSQDAARASLER--LGL------DYVDLYLIHWPAGD 121
Query: 531 HVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGLEKPSALQIE 680
H ++D+W G++ AK+ G+ +SIG+ NFN E + IID P+ QIE
Sbjct: 122 HGKYIDSWGGLMKAKQDGVARSIGVCNFNAEHLSNIIDLSFFTPAINQIE 171
Score = 45.6 bits (103), Expect = 0.002
Identities = 28/67 (41%), Positives = 41/67 (61%)
Frame = +2
Query: 137 VPTLQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIE 316
+P++ L+ G +IPV+ LG G++ + + E++V ALEAGY IDTA YG E
Sbjct: 11 IPSVSLNDGHSIPVLGLGV-------GELSEA--EAERSVAAALEAGYRLIDTAAVYGNE 61
Query: 317 DQVGRAL 337
VGRA+
Sbjct: 62 AAVGRAV 68
>UniRef50_Q1U9L6 Cluster: 2,5-didehydrogluconate reductase; n=3;
Lactobacillus|Rep: 2,5-didehydrogluconate reductase -
Lactobacillus reuteri 100-23
Length = 288
Score = 53.6 bits (123), Expect = 7e-06
Identities = 34/110 (30%), Positives = 55/110 (50%), Gaps = 2/110 (1%)
Frame = +3
Query: 357 GLKRESIFITTKLWNSYHEREQVIPALRKSLXKSQLGIRRPVFDSLAHSYV*ERYLARHV 536
G+KRE +F+T+KLWN+ EQ A +++L + Q+ + L H E+
Sbjct: 69 GIKREDLFVTSKLWNTNRGYEQTKKAFQETLDRLQMDY---LDLYLIHWPANEKQFGDDA 125
Query: 537 DFL--DTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGLEKPSALQIE 680
+ +TWR M D G ++IG+SNF I ++ + P+ QIE
Sbjct: 126 AKINAETWRAMEDLYNEGKIRAIGVSNFMPHHIAELMKTAKVAPAVDQIE 175
Score = 45.2 bits (102), Expect = 0.003
Identities = 29/72 (40%), Positives = 38/72 (52%)
Frame = +2
Query: 143 TLQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQ 322
T L++G IP V GT+ R V EQAV A+E GY HIDTA YG E+
Sbjct: 10 TFNLNNGVKIPCVGYGTF---RTPADVA------EQAVKEAIETGYRHIDTAAVYGNEEA 60
Query: 323 VGRALXQEILRR 358
VG+ + ++R
Sbjct: 61 VGKGIKDSGIKR 72
>UniRef50_Q0IBY6 Cluster: Alcohol dehydrogenase; n=2;
Chroococcales|Rep: Alcohol dehydrogenase - Synechococcus
sp. (strain CC9311)
Length = 336
Score = 53.6 bits (123), Expect = 7e-06
Identities = 34/116 (29%), Positives = 55/116 (47%), Gaps = 9/116 (7%)
Frame = +3
Query: 360 LKRESIFITTKLWNSYHEREQVIPALRKSLXKSQLGIRRPVFDSLAHSYV*ERYLARHVD 539
+ R ++IT+KLW++ H + V AL +SL + E+ A VD
Sbjct: 85 ITRSELWITSKLWSNCHGKNHVEAALSQSLQNLGVDYLNLYLIHWPVGIRPEKTFAESVD 144
Query: 540 FL---------DTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGLEKPSALQIE 680
L +TW M + GLTK IG+SNF +++Q+++ +KP Q+E
Sbjct: 145 DLLTPEESPISETWEAMESTRDKGLTKHIGVSNFTVKKLQQLVSHCKQKPEVNQVE 200
Score = 40.7 bits (91), Expect = 0.056
Identities = 27/75 (36%), Positives = 41/75 (54%), Gaps = 3/75 (4%)
Frame = +2
Query: 134 IVPTLQ---LSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYK 304
++PT+Q LS+G +P++ LGT K + QV +A+ + GY HID A
Sbjct: 15 VIPTMQYASLSNGDRMPLLGLGTG-----KSESRQVYKSVREAI----KIGYRHIDCASI 65
Query: 305 YGIEDQVGRALXQEI 349
YG E++VG A+ I
Sbjct: 66 YGNEEEVGDAIRDAI 80
Score = 34.7 bits (76), Expect = 3.7
Identities = 12/29 (41%), Positives = 20/29 (68%)
Frame = +1
Query: 448 LXNLNLEYVDLYLIHWPIAMFENDTLLDT 534
L NL ++Y++LYLIHWP+ + T ++
Sbjct: 114 LQNLGVDYLNLYLIHWPVGIRPEKTFAES 142
>UniRef50_A7CWF9 Cluster: Aldehyde reductase; n=2; Bacteria|Rep:
Aldehyde reductase - Opitutaceae bacterium TAV2
Length = 347
Score = 53.6 bits (123), Expect = 7e-06
Identities = 36/121 (29%), Positives = 55/121 (45%), Gaps = 13/121 (10%)
Frame = +3
Query: 357 GLKRESIFITTKLWNSYHEREQVIPALRKSLXKSQL-------------GIRRPVFDSLA 497
G++RE ++IT+KLWN H VIPA KSL L P D +
Sbjct: 85 GIRREDLWITSKLWNDKHAEADVIPAFEKSLRDLGLDYLDLYLIHWPFPNFHPPGCDVSS 144
Query: 498 HSYV*ERYLARHVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGLEKPSALQI 677
S Y+ H +F+ TWR + GL + IG SN ++Q ++ +P+ ++
Sbjct: 145 RSPDARPYI--HAEFMKTWRQLETLHDRGLVRHIGTSNMTIAKLQLLLRDARVRPAVNEM 202
Query: 678 E 680
E
Sbjct: 203 E 203
Score = 35.1 bits (77), Expect = 2.8
Identities = 22/76 (28%), Positives = 34/76 (44%), Gaps = 1/76 (1%)
Frame = +2
Query: 137 VPTLQLSSGGNIPVVALGTW-LGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGI 313
+P L+SG +P + +GT+ H G+V +V A E GY H D A Y
Sbjct: 16 IPQRTLASGARMPAIGMGTFGSDHAAPGEVAA-------SVYAAAELGYRHFDCAAVYSN 68
Query: 314 EDQVGRALXQEILRRT 361
E ++G + + T
Sbjct: 69 EREIGATFRRILTSNT 84
Score = 34.7 bits (76), Expect = 3.7
Identities = 13/21 (61%), Positives = 16/21 (76%)
Frame = +1
Query: 448 LXNLNLEYVDLYLIHWPIAMF 510
L +L L+Y+DLYLIHWP F
Sbjct: 115 LRDLGLDYLDLYLIHWPFPNF 135
>UniRef50_Q17G72 Cluster: Aldo-keto reductase; n=9;
Endopterygota|Rep: Aldo-keto reductase - Aedes aegypti
(Yellowfever mosquito)
Length = 316
Score = 53.6 bits (123), Expect = 7e-06
Identities = 24/48 (50%), Positives = 34/48 (70%)
Frame = +3
Query: 537 DFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGLEKPSALQIE 680
D + W+ M + + GL ++IG+SNFNQ QIQRI+D+ KP+ LQIE
Sbjct: 139 DHVALWKAMEEVYEAGLARNIGLSNFNQRQIQRILDNCQIKPANLQIE 186
Score = 37.9 bits (84), Expect = 0.40
Identities = 22/66 (33%), Positives = 32/66 (48%)
Frame = +2
Query: 146 LQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQV 325
+ +G +P + GTW + E+A+ ALEAGY HIDTA Y E +
Sbjct: 7 ITFENGTTMPALGFGTWRAS---------DEEVEKALNEALEAGYRHIDTAPVYLNEKTI 57
Query: 326 GRALXQ 343
G+ L +
Sbjct: 58 GKVLKE 63
>UniRef50_A7SIT3 Cluster: Predicted protein; n=1; Nematostella
vectensis|Rep: Predicted protein - Nematostella
vectensis
Length = 323
Score = 53.6 bits (123), Expect = 7e-06
Identities = 39/122 (31%), Positives = 67/122 (54%), Gaps = 12/122 (9%)
Frame = +3
Query: 351 SEG-LKRESIFITTKLWNSYHEREQVIPALRKSLXKSQLG------IRRPV-FDS---LA 497
+EG +KRE +F+T+KLW H + V+PA + +L QL I PV F L
Sbjct: 67 TEGKVKREELFVTSKLWCDSHHPDDVLPACQATLKNLQLDYLDLYLIHIPVAFKKGVRLP 126
Query: 498 HSYV*ERYLARHVDFL-DTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGLEKPSALQ 674
HS + E + + + +TW+ M GL K+IG+SNF+ +++ +++++ P+ Q
Sbjct: 127 HS-IAEGIIGYTPEGVQNTWQAMEGLVAKGLCKAIGVSNFSVKRLNKLLETASIVPACNQ 185
Query: 675 IE 680
+E
Sbjct: 186 VE 187
Score = 47.6 bits (108), Expect = 5e-04
Identities = 30/78 (38%), Positives = 43/78 (55%)
Frame = +2
Query: 149 QLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQVG 328
+L++G +IP +ALGTW + +V N AV A+E GY HID A YG E ++G
Sbjct: 9 KLNTGASIPAMALGTWQSSKE-----EVGN----AVRLAIELGYRHIDCAEIYGNEGEIG 59
Query: 329 RALXQEILRRT*KRIYLY 382
AL + + KR L+
Sbjct: 60 EALSEVLTEGKVKREELF 77
>UniRef50_Q96JD6 Cluster: Aldo-keto reductase family 1 member C-like
protein 2; n=37; Euteleostomi|Rep: Aldo-keto reductase
family 1 member C-like protein 2 - Homo sapiens (Human)
Length = 320
Score = 53.6 bits (123), Expect = 7e-06
Identities = 27/50 (54%), Positives = 34/50 (68%), Gaps = 2/50 (4%)
Frame = +3
Query: 537 DFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDS-GLE-KPSALQIE 680
DFLDTW M D GL K+IG+SNFN EQ++R+++ GL KP QIE
Sbjct: 147 DFLDTWEAMEDLVITGLVKNIGVSNFNHEQLERLLNKPGLRFKPLTNQIE 196
Score = 37.1 bits (82), Expect = 0.70
Identities = 24/62 (38%), Positives = 32/62 (51%)
Frame = +2
Query: 164 GNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQVGRALXQ 343
G+IP V L +W GKV + AV A++AGY H D AY Y E +VG +
Sbjct: 2 GDIPAVGLSSWKAS--PGKVTE-------AVKEAIDAGYRHFDCAYFYHNEREVGAGIRC 52
Query: 344 EI 349
+I
Sbjct: 53 KI 54
Score = 37.1 bits (82), Expect = 0.70
Identities = 19/41 (46%), Positives = 26/41 (63%), Gaps = 1/41 (2%)
Frame = +3
Query: 345 KFSEG-LKRESIFITTKLWNSYHEREQVIPALRKSLXKSQL 464
K EG ++RE +FI TKLW + H++ V A RKSL +L
Sbjct: 53 KIKEGAVRREDLFIATKLWCTCHKKSLVETACRKSLKALKL 93
>UniRef50_UPI0000E4A7CE Cluster: PREDICTED: similar to LOC553452
protein; n=6; Strongylocentrotus purpuratus|Rep:
PREDICTED: similar to LOC553452 protein -
Strongylocentrotus purpuratus
Length = 321
Score = 52.8 bits (121), Expect = 1e-05
Identities = 40/125 (32%), Positives = 63/125 (50%), Gaps = 13/125 (10%)
Frame = +3
Query: 345 KFSEG-LKRESIFITTKLWNSYHEREQVIPALRKSLXKSQLGIRRPVFDSLAHSYV*ER- 518
K +G +KRE +F+T+KLW + +V P+ R+SL L S V +
Sbjct: 65 KIDDGTIKREDLFVTSKLWVTDSHPSRVEPSCRQSLSDLGLAYLDLFLIHCPTSAVGGKG 124
Query: 519 ---------YLARH-VDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGLEKPSA 668
++ +D++DTWR M GL ++IG+SNF QIQR++D + P A
Sbjct: 125 PFPMDDNGLFIGDDTIDYVDTWRIMESLVDKGLVRAIGVSNFTVAQIQRVLDLPPKYPIA 184
Query: 669 -LQIE 680
+Q+E
Sbjct: 185 NVQVE 189
Score = 35.5 bits (78), Expect = 2.1
Identities = 25/78 (32%), Positives = 37/78 (47%), Gaps = 1/78 (1%)
Frame = +2
Query: 152 LSSGGNIPVVALGTW-LGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQVG 328
L G +P++ GTW + G+V++ A++ GY HID A YG E VG
Sbjct: 10 LPGGRKLPLLGFGTWQIKPEEVGRVIET----------AIDCGYRHIDEASLYGNEKGVG 59
Query: 329 RALXQEILRRT*KRIYLY 382
+ +I T KR L+
Sbjct: 60 DGIKAKIDDGTIKREDLF 77
>UniRef50_Q9HGY0 Cluster: Glycerol dehydrogenase; n=8;
Saccharomycetaceae|Rep: Glycerol dehydrogenase -
Zygosaccharomyces rouxii (Candida mogii)
Length = 310
Score = 52.8 bits (121), Expect = 1e-05
Identities = 32/65 (49%), Positives = 41/65 (63%)
Frame = +2
Query: 143 TLQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQ 322
TL+L++G IP V LGTW R K N+ +AVI AL+AGY HID A YG E +
Sbjct: 10 TLKLNTGQTIPQVGLGTW---RSK------ENEGYKAVIEALKAGYRHIDGAAVYGNEGE 60
Query: 323 VGRAL 337
VG+A+
Sbjct: 61 VGKAI 65
>UniRef50_Q8ZH36 Cluster: 2,5-diketo-D-gluconic acid reductase B;
n=91; Proteobacteria|Rep: 2,5-diketo-D-gluconic acid
reductase B - Yersinia pestis
Length = 267
Score = 52.8 bits (121), Expect = 1e-05
Identities = 37/120 (30%), Positives = 65/120 (54%), Gaps = 2/120 (1%)
Frame = +3
Query: 327 EGPXTKKFSE-GLKRESIFITTKLWNSYHEREQVIPALRKSLXKSQLGIRRPVFDSLAHS 503
E P + E G+ R+ +FITTK+W + ++++IP+LR+S+ K ++ D
Sbjct: 42 EAPVGQAIQESGINRDELFITTKIWIANLSKDKLIPSLRESIQK----LKTDYVDLTLIH 97
Query: 504 YV*ERYLARHVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDS-GLEKPSALQIE 680
+ +F+ ++ AK LGLT+ IGISNF + +++ I + G E+ + QIE
Sbjct: 98 WPSPNDEVSVAEFMSE---LLKAKGLGLTRQIGISNFTIDLMKQAIAAVGAEEIATNQIE 154
>UniRef50_UPI00015B4B22 Cluster: PREDICTED: similar to GA15457-PA;
n=1; Nasonia vitripennis|Rep: PREDICTED: similar to
GA15457-PA - Nasonia vitripennis
Length = 388
Score = 52.4 bits (120), Expect = 2e-05
Identities = 44/124 (35%), Positives = 61/124 (49%), Gaps = 11/124 (8%)
Frame = +3
Query: 342 KKFSEGLKRESIFITTKLWNSYHEREQVIPALRKSLXKSQLG------IRRPVF----DS 491
K F +G KRE IFIT+KL + + + V L++SL L I P ++
Sbjct: 82 KWFDKGGKREDIFITSKLPSQGNRPQSVETYLKRSLKDLGLDYVDMYLIHTPFAVKEGEN 141
Query: 492 LAHSYV*E-RYLARHVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGLEKPSA 668
L+ + L VD W+ M K G KSIG+SNFNQ Q+ I ++ KPS
Sbjct: 142 LSSKQDKDGNDLFDDVDHKALWKAMERQVKEGRAKSIGLSNFNQSQVLNIYNNAEIKPSN 201
Query: 669 LQIE 680
LQ+E
Sbjct: 202 LQVE 205
Score = 44.8 bits (101), Expect = 0.003
Identities = 27/67 (40%), Positives = 38/67 (56%)
Frame = +2
Query: 137 VPTLQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIE 316
V L+LSSG IP V LGT +++ ++ + A+ ALE GY HIDTA+ Y E
Sbjct: 23 VEKLKLSSGHEIPAVGLGT--------STIKL-DEMDNAISSALENGYRHIDTAFSYDNE 73
Query: 317 DQVGRAL 337
+G+ L
Sbjct: 74 AAIGKIL 80
Score = 33.9 bits (74), Expect = 6.5
Identities = 14/26 (53%), Positives = 19/26 (73%)
Frame = +1
Query: 448 LXNLNLEYVDLYLIHWPIAMFENDTL 525
L +L L+YVD+YLIH P A+ E + L
Sbjct: 117 LKDLGLDYVDMYLIHTPFAVKEGENL 142
>UniRef50_UPI00015B4912 Cluster: PREDICTED: similar to aldo-keto
reductase; n=1; Nasonia vitripennis|Rep: PREDICTED:
similar to aldo-keto reductase - Nasonia vitripennis
Length = 353
Score = 52.4 bits (120), Expect = 2e-05
Identities = 46/124 (37%), Positives = 60/124 (48%), Gaps = 13/124 (10%)
Frame = +3
Query: 348 FSEGLKRESIFITTKLWNSYHEREQVIPALRKSLXKSQLG------IRRPVF-----DS- 491
F++G KRE IF+T+KL + E V ++ SL K L I P DS
Sbjct: 89 FAKGGKREDIFVTSKLPYYDNHPESVEKYIKLSLEKLGLQYLDMYLIHAPFAVHHKEDSY 148
Query: 492 -LAHSYV*ERYLARHVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGLEKPSA 668
LA + L D + W+ M K G TKSIG+SNFN+ QI I+ KPS
Sbjct: 149 ELATNEDGSVVLDTQTDPIAVWKEMEKQVKEGRTKSIGLSNFNETQITNILKEAKIKPSN 208
Query: 669 LQIE 680
LQ+E
Sbjct: 209 LQVE 212
Score = 38.3 bits (85), Expect = 0.30
Identities = 25/63 (39%), Positives = 34/63 (53%)
Frame = +2
Query: 149 QLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQVG 328
+LSSG N P+V LGT H V+ E + ALE G HIDT++ Y E+ +G
Sbjct: 32 RLSSGHNFPIVGLGT---HGLNEDVL------ETVLTGALEKGIGHIDTSFVYKNEETIG 82
Query: 329 RAL 337
+ L
Sbjct: 83 KVL 85
>UniRef50_Q7WSY4 Cluster: Putative aldo-keto reductase; n=1;
Propionibacterium freudenreichii subsp. shermanii|Rep:
Putative aldo-keto reductase - Propionibacterium
freudenreichii subsp. shermanii
Length = 280
Score = 52.4 bits (120), Expect = 2e-05
Identities = 34/108 (31%), Positives = 54/108 (50%)
Frame = +3
Query: 357 GLKRESIFITTKLWNSYHEREQVIPALRKSLXKSQLGIRRPVFDSLAHSYV*ERYLARHV 536
G R IF+TTK +H R+ V AL SL + LG+ ++ +
Sbjct: 69 GPDRAEIFVTTKFSKQWHSRKGVHEALEHSLER--LGL------DYVDLFLMHWPMPGEG 120
Query: 537 DFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGLEKPSALQIE 680
++D +RGM++ K+ GL K+IG+SNF + +I G+ P QI+
Sbjct: 121 SYVDAYRGMVELKEQGLAKAIGVSNFKVHHLDDLITEGM-TPEVNQIQ 167
Score = 46.4 bits (105), Expect = 0.001
Identities = 26/68 (38%), Positives = 40/68 (58%)
Frame = +2
Query: 140 PTLQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIED 319
PT++LS G +P++ +GTW KG+ + AV A+E GY +DTA YG E+
Sbjct: 9 PTVELSGGTRMPMLGMGTW---PLKGE------ECRAAVASAIEQGYRLVDTAEAYGNEE 59
Query: 320 QVGRALXQ 343
VG+A+ +
Sbjct: 60 AVGKAVRE 67
>UniRef50_Q17DN1 Cluster: Aldo-keto reductase; n=1; Aedes
aegypti|Rep: Aldo-keto reductase - Aedes aegypti
(Yellowfever mosquito)
Length = 284
Score = 52.4 bits (120), Expect = 2e-05
Identities = 28/70 (40%), Positives = 42/70 (60%)
Frame = +2
Query: 140 PTLQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIED 319
P ++L++G +PV+ LGTWL +G +A+ A++AGY HIDTAY Y E
Sbjct: 6 PMVKLNNGLEMPVLGLGTWLSKEGEGV---------EAIKAAIDAGYRHIDTAYFYQNEK 56
Query: 320 QVGRALXQEI 349
+VG A+ +I
Sbjct: 57 EVGEAIRAKI 66
Score = 52.4 bits (120), Expect = 2e-05
Identities = 24/49 (48%), Positives = 31/49 (63%)
Frame = +3
Query: 534 VDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGLEKPSALQIE 680
VD++DTW+ M K G KSIG+SNFN EQI R++ KP Q+E
Sbjct: 104 VDYIDTWKAMEKLLKTGKVKSIGVSNFNSEQITRLLAECEIKPVTNQVE 152
>UniRef50_Q9P6D3 Cluster: Related to aldo-keto reductase YPR1; n=10;
Pezizomycotina|Rep: Related to aldo-keto reductase YPR1
- Neurospora crassa
Length = 322
Score = 52.4 bits (120), Expect = 2e-05
Identities = 27/77 (35%), Positives = 42/77 (54%), Gaps = 1/77 (1%)
Frame = +2
Query: 134 IVPTLQLSSGGNIPVVALGTWLGHRPKGKVVQ-VTNDTEQAVIYALEAGYTHIDTAYKYG 310
++P+L+LS G IP++ G + G ++ A + AL AGY H+D A YG
Sbjct: 23 LIPSLKLSDGNEIPMLGYGLGTANYKSGDSADTISEPIVNATLTALNAGYAHLDGAEVYG 82
Query: 311 IEDQVGRALXQEILRRT 361
E ++GRA+ Q L R+
Sbjct: 83 NEVELGRAIAQSKLPRS 99
Score = 39.1 bits (87), Expect = 0.17
Identities = 39/111 (35%), Positives = 55/111 (49%), Gaps = 4/111 (3%)
Frame = +3
Query: 360 LKRESIFITTKLWNSYHEREQVIPALRKSLXKSQLGIRRPVFDSLAHSYV*ERYLARHVD 539
L R S++ITTK + V + +SL K LG+ V L HS + A++ +
Sbjct: 96 LPRSSLYITTK--TIVRAGDTVTQSFNRSLEK--LGLDY-VDLYLLHS----PFFAKNPE 146
Query: 540 FLDT-WRGMIDAKKLGLTKSIGISNFNQEQIQRIID--SGLEKPSAL-QIE 680
L WR M K G+ KSIG+SNF +Q + D GL+ P + QIE
Sbjct: 147 QLQAAWREMEKIKDSGMAKSIGVSNFLISHLQTLFDIPGGLQYPPVVNQIE 197
>UniRef50_Q4PDR0 Cluster: Putative uncharacterized protein; n=1;
Ustilago maydis|Rep: Putative uncharacterized protein -
Ustilago maydis (Smut fungus)
Length = 339
Score = 52.4 bits (120), Expect = 2e-05
Identities = 25/75 (33%), Positives = 43/75 (57%)
Frame = +2
Query: 137 VPTLQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIE 316
+P+ L++G +P V +G W G G+ N+ A++ A++ GY H+DTA Y E
Sbjct: 5 IPSFTLNTGAKLPSVGMGCWQGQPGPGR----DNELVDALVRAIKVGYRHLDTATGYRNE 60
Query: 317 DQVGRALXQEILRRT 361
+VG+A+ Q + R+
Sbjct: 61 AEVGQAVRQSGVARS 75
>UniRef50_A5E082 Cluster: GCY protein; n=4; Saccharomycetales|Rep:
GCY protein - Lodderomyces elongisporus (Yeast)
(Saccharomyces elongisporus)
Length = 295
Score = 52.4 bits (120), Expect = 2e-05
Identities = 29/65 (44%), Positives = 36/65 (55%)
Frame = +2
Query: 143 TLQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQ 322
T L++G IP + LGTWL +A + AL+ GY HIDTA YG EDQ
Sbjct: 11 TYTLNNGLKIPAIGLGTWLADEEDAAY--------KATLTALKNGYKHIDTAAAYGNEDQ 62
Query: 323 VGRAL 337
VGRA+
Sbjct: 63 VGRAI 67
Score = 52.0 bits (119), Expect = 2e-05
Identities = 31/99 (31%), Positives = 52/99 (52%), Gaps = 2/99 (2%)
Frame = +3
Query: 357 GLKRESIFITTKLWNSYH-EREQVIPALRKSLXKSQLGIRRPVFDSLAHSYV*ERYLARH 533
G+ R+ IF+TTKLWN H + E + K L + + + + Y
Sbjct: 71 GVSRDEIFVTTKLWNDQHKDPEGALDESLKKLGLEYVDLYLIHWPLSVDPKTEKPY--DD 128
Query: 534 VDFLDTWRGMIDAKKLG-LTKSIGISNFNQEQIQRIIDS 647
DF+DTWR + K G K+IG+SNFN++++ ++++S
Sbjct: 129 YDFVDTWRNLQKIYKEGKKVKAIGVSNFNKKKLDKLLNS 167
Score = 37.9 bits (84), Expect = 0.40
Identities = 17/37 (45%), Positives = 24/37 (64%), Gaps = 7/37 (18%)
Frame = +1
Query: 448 LXNLNLEYVDLYLIHWPIAM-------FENDTLLDTW 537
L L LEYVDLYLIHWP+++ +++ +DTW
Sbjct: 99 LKKLGLEYVDLYLIHWPLSVDPKTEKPYDDYDFVDTW 135
>UniRef50_A7BA05 Cluster: Putative uncharacterized protein; n=1;
Actinomyces odontolyticus ATCC 17982|Rep: Putative
uncharacterized protein - Actinomyces odontolyticus ATCC
17982
Length = 292
Score = 52.0 bits (119), Expect = 2e-05
Identities = 32/67 (47%), Positives = 37/67 (55%)
Frame = +2
Query: 137 VPTLQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIE 316
+PT L +G IPV+ GT+ KV DT AV ALE GY HIDTA YG E
Sbjct: 16 IPTFMLPTGSPIPVLGFGTY-------KVAP--EDTYDAVSRALEVGYRHIDTAQMYGNE 66
Query: 317 DQVGRAL 337
+VG AL
Sbjct: 67 AEVGAAL 73
Score = 51.2 bits (117), Expect = 4e-05
Identities = 34/111 (30%), Positives = 56/111 (50%), Gaps = 1/111 (0%)
Frame = +3
Query: 351 SEGLKRESIFITTKLWNSYHEREQVIPALRKSLXKSQLGIRRPVFD-SLAHSYV*ERYLA 527
+ G+ RE +FITTK+ NS HE ++ ++R+SL +R D L H + Y
Sbjct: 75 ASGIAREDLFITTKVDNSNHEPDRAAASIRRSLE----DLRTDYVDLLLVHWPLPTLYGG 130
Query: 528 RHVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGLEKPSALQIE 680
D W + DA G ++IG+SN+ +E ++ + + P LQ+E
Sbjct: 131 ---DVALPWPALEDAFNAGGARAIGLSNYEREHVEAVREVATVAPHVLQVE 178
>UniRef50_Q55FL3 Cluster: Aldo-keto reductase; n=2; Dictyostelium
discoideum AX4|Rep: Aldo-keto reductase - Dictyostelium
discoideum AX4
Length = 321
Score = 52.0 bits (119), Expect = 2e-05
Identities = 41/127 (32%), Positives = 63/127 (49%), Gaps = 16/127 (12%)
Frame = +3
Query: 348 FSEG-LKRESIFITTKLWNSYHEREQVIPALRKSLXKSQLG------IRRPV-FDS---- 491
F EG +KRE IF T+KLWNS H V+ K++ +G I P+ F++
Sbjct: 76 FKEGEIKREDIFYTSKLWNSCHNSNLVVKHCVKTIEDLGIGYLDLYLIHWPIAFENSNPL 135
Query: 492 -LAHSYV*ERY---LARHVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGLEK 659
L + ++ + V +TW+ M +LGL KSIG+SNFN + + ++ K
Sbjct: 136 GLTIEPLRDQNGNPIIAPVSIRETWQEMEKLVELGLVKSIGVSNFNVQNLVDLLTYAKIK 195
Query: 660 PSALQIE 680
P Q+E
Sbjct: 196 PVVNQVE 202
Score = 39.5 bits (88), Expect = 0.13
Identities = 24/65 (36%), Positives = 34/65 (52%)
Frame = +2
Query: 149 QLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQVG 328
+L+ G IP + LGT+ P G+V N+ AL+ GY HID A YG E +G
Sbjct: 18 KLNDGNQIPSIGLGTYYSENP-GEVGDAINN-------ALKNGYRHIDGAAFYGNEKVIG 69
Query: 329 RALXQ 343
+L +
Sbjct: 70 NSLKE 74
Score = 36.3 bits (80), Expect = 1.2
Identities = 16/27 (59%), Positives = 20/27 (74%)
Frame = +1
Query: 448 LXNLNLEYVDLYLIHWPIAMFENDTLL 528
+ +L + Y+DLYLIHWPIA FEN L
Sbjct: 110 IEDLGIGYLDLYLIHWPIA-FENSNPL 135
>UniRef50_P14065 Cluster: Protein GCY; n=13; Saccharomycetales|Rep:
Protein GCY - Saccharomyces cerevisiae (Baker's yeast)
Length = 312
Score = 52.0 bits (119), Expect = 2e-05
Identities = 29/64 (45%), Positives = 37/64 (57%)
Frame = +2
Query: 146 LQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQV 325
L L++G IP + LGTW ND +AV+ AL+ GY HIDTA Y EDQV
Sbjct: 12 LSLNTGAQIPQIGLGTWQSKE---------NDAYKAVLTALKDGYRHIDTAAIYRNEDQV 62
Query: 326 GRAL 337
G+A+
Sbjct: 63 GQAI 66
Score = 45.2 bits (102), Expect = 0.003
Identities = 38/126 (30%), Positives = 62/126 (49%), Gaps = 18/126 (14%)
Frame = +3
Query: 357 GLKRESIFITTKLW-NSYHEREQVIPALRKSLXKSQLGIRRPVFDS-LAHSYV*ERYL-- 524
G+ RE IF+TTKLW +HE E + K L + + + + L +Y+ +
Sbjct: 70 GVPREEIFVTTKLWCTQHHEPEVALDQSLKRLGLDYVDLYLMHWPARLDPAYIKNEDILS 129
Query: 525 -------ARHVD-----FLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGLEK--P 662
+R VD F+ TW M + K G TK++G+SNF+ ++ ++ S K P
Sbjct: 130 VPTKKDGSRAVDITNWNFIKTWELMQELPKTGKTKAVGVSNFSINNLKDLLASQGNKLTP 189
Query: 663 SALQIE 680
+A Q+E
Sbjct: 190 AANQVE 195
>UniRef50_UPI000065D0BD Cluster: Homolog of Homo sapiens "AKR1B1
protein.; n=1; Takifugu rubripes|Rep: Homolog of Homo
sapiens "AKR1B1 protein. - Takifugu rubripes
Length = 330
Score = 51.6 bits (118), Expect = 3e-05
Identities = 33/83 (39%), Positives = 47/83 (56%)
Frame = +2
Query: 134 IVPTLQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGI 313
++P++ L++G +PV+ LGTW GK V T +AV A+ AGY HIDTAY Y
Sbjct: 1 MIPSVTLNTGALMPVLGLGTW----KSGKGV-----TTEAVKVAIGAGYRHIDTAYVYEN 51
Query: 314 EDQVGRALXQEILRRT*KRIYLY 382
E +VG + I + KR L+
Sbjct: 52 ETEVGAGVQAMIDQGVVKREELF 74
Score = 49.2 bits (112), Expect = 2e-04
Identities = 25/49 (51%), Positives = 35/49 (71%), Gaps = 2/49 (4%)
Frame = +3
Query: 540 FLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDS-GLE-KPSALQIE 680
FLDTW M + GL K+IGISNFN++QI+ +++ GL+ KP+ QIE
Sbjct: 162 FLDTWEAMEELVDDGLAKAIGISNFNKDQIEAVLNKPGLKHKPATNQIE 210
>UniRef50_Q96JD6-2 Cluster: Isoform 2 of Q96JD6 ; n=4;
Catarrhini|Rep: Isoform 2 of Q96JD6 - Homo sapiens
(Human)
Length = 263
Score = 51.6 bits (118), Expect = 3e-05
Identities = 26/49 (53%), Positives = 33/49 (67%), Gaps = 2/49 (4%)
Frame = +3
Query: 537 DFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDS-GLE-KPSALQI 677
DFLDTW M D GL K+IG+SNFN EQ++R+++ GL KP QI
Sbjct: 147 DFLDTWEAMEDLVITGLVKNIGVSNFNHEQLERLLNKPGLRFKPLTNQI 195
Score = 37.1 bits (82), Expect = 0.70
Identities = 24/62 (38%), Positives = 32/62 (51%)
Frame = +2
Query: 164 GNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQVGRALXQ 343
G+IP V L +W GKV + AV A++AGY H D AY Y E +VG +
Sbjct: 2 GDIPAVGLSSWKAS--PGKVTE-------AVKEAIDAGYRHFDCAYFYHNEREVGAGIRC 52
Query: 344 EI 349
+I
Sbjct: 53 KI 54
Score = 37.1 bits (82), Expect = 0.70
Identities = 19/41 (46%), Positives = 26/41 (63%), Gaps = 1/41 (2%)
Frame = +3
Query: 345 KFSEG-LKRESIFITTKLWNSYHEREQVIPALRKSLXKSQL 464
K EG ++RE +FI TKLW + H++ V A RKSL +L
Sbjct: 53 KIKEGAVRREDLFIATKLWCTCHKKSLVETACRKSLKALKL 93
>UniRef50_A5VK30 Cluster: 2,5-didehydrogluconate reductase; n=2;
Lactobacillus reuteri|Rep: 2,5-didehydrogluconate
reductase - Lactobacillus reuteri F275
Length = 300
Score = 51.6 bits (118), Expect = 3e-05
Identities = 37/109 (33%), Positives = 59/109 (54%), Gaps = 1/109 (0%)
Frame = +3
Query: 357 GLKRESIFITTKLWNSYH-EREQVIPALRKSLXKSQLGIRRPVFDSLAHSYV*ERYLARH 533
G KR+SIF+TTK++N + +++ A+ + L K Q V L H V ++Y
Sbjct: 75 GRKRDSIFLTTKIFNGDQGDYDKLRQAVNEQLKKLQTNY---VDLLLLHWPVNDKYN--- 128
Query: 534 VDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGLEKPSALQIE 680
++WR + D K G K+IG+ NFN E++ ++D KP+ QIE
Sbjct: 129 ----ESWRALEDIYKDGQAKAIGVCNFNVERMTDLLDHAKIKPAINQIE 173
Score = 35.1 bits (77), Expect = 2.8
Identities = 23/66 (34%), Positives = 35/66 (53%)
Frame = +2
Query: 140 PTLQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIED 319
P ++L++G IP + LG W K + + T+Q V A+ Y IDTA +YG E
Sbjct: 11 PKIKLNNGHLIPQLGLGVW-----KASLAE----TQQMVKEAIMNDYVLIDTAKQYGNEA 61
Query: 320 QVGRAL 337
VG+ +
Sbjct: 62 AVGQGI 67
>UniRef50_Q05KR9 Cluster: Benzil reductase; n=5; Bacillales|Rep:
Benzil reductase - Bacillus subtilis
Length = 276
Score = 51.2 bits (117), Expect = 4e-05
Identities = 34/108 (31%), Positives = 52/108 (48%)
Frame = +3
Query: 357 GLKRESIFITTKLWNSYHEREQVIPALRKSLXKSQLGIRRPVFDSLAHSYV*ERYLARHV 536
G+ RE +FIT+K+WN E + A KSL + QL + L H ++Y
Sbjct: 68 GVAREELFITSKVWNEDQGYETTLAAFEKSLERLQLDY---LDLYLIHWPGKDKY----- 119
Query: 537 DFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGLEKPSALQIE 680
DTWR + K G ++IG+SNF ++ ++ KP Q+E
Sbjct: 120 --KDTWRALEKLYKDGKIRAIGVSNFQVHHLEELLKDAEIKPMVNQVE 165
Score = 35.1 bits (77), Expect = 2.8
Identities = 16/30 (53%), Positives = 18/30 (60%)
Frame = +1
Query: 448 LXNLNLEYVDLYLIHWPIAMFENDTLLDTW 537
L L L+Y+DLYLIHWP D DTW
Sbjct: 98 LERLQLDYLDLYLIHWP----GKDKYKDTW 123
>UniRef50_A3JU52 Cluster: 2,5-diketo-D-gluconic acid reductase A;
n=1; Rhodobacterales bacterium HTCC2150|Rep:
2,5-diketo-D-gluconic acid reductase A - Rhodobacterales
bacterium HTCC2150
Length = 334
Score = 51.2 bits (117), Expect = 4e-05
Identities = 35/115 (30%), Positives = 55/115 (47%), Gaps = 5/115 (4%)
Frame = +3
Query: 351 SEGLKRESIFITTKLWNSYHEREQVIPALRKSLXKSQLGIRRPVFDSLAHSYV*ERYLAR 530
S G+ R+ +F+T KLW ++L + + R L YV + YL
Sbjct: 100 SAGITRKDLFVTAKLWPGNPAWGDAPKTKAQTLDECDASLAR-----LGLDYV-DLYLI- 152
Query: 531 HVDF-----LDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGLEKPSALQIE 680
H + L+ WR +++ + G +SIG+SNFN+ + I +GL P A QIE
Sbjct: 153 HAPYGGDMRLEQWRALLELQANGKARSIGVSNFNESHLNEIKAAGLPMPDANQIE 207
Score = 35.9 bits (79), Expect = 1.6
Identities = 24/66 (36%), Positives = 34/66 (51%), Gaps = 1/66 (1%)
Frame = +2
Query: 143 TLQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYA-LEAGYTHIDTAYKYGIED 319
T L++ IP V GT+L ++ND ++ I A ++AGY HIDTA Y E
Sbjct: 39 TFTLNTTTTIPAVGFGTYL----------ISNDDAKSTISAAIQAGYRHIDTASGYQNEK 88
Query: 320 QVGRAL 337
VG +
Sbjct: 89 TVGAGI 94
>UniRef50_Q6CEJ0 Cluster: Yarrowia lipolytica chromosome B of strain
CLIB122 of Yarrowia lipolytica; n=1; Yarrowia
lipolytica|Rep: Yarrowia lipolytica chromosome B of
strain CLIB122 of Yarrowia lipolytica - Yarrowia
lipolytica (Candida lipolytica)
Length = 302
Score = 51.2 bits (117), Expect = 4e-05
Identities = 38/115 (33%), Positives = 59/115 (51%), Gaps = 1/115 (0%)
Frame = +2
Query: 131 LIVPTLQLSSGGNIPVVALGTWLG-HRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKY 307
+ VP ++LS+G IP + G+ RP G+ + + AV+ A+ AG+ HIDTA Y
Sbjct: 1 MTVPKVKLSNGLEIPAIGFGSGTKWKRPPGEKEE--RELIDAVVSAINAGHLHIDTAEFY 58
Query: 308 GIEDQVGRALXQEILRRT*KRIYLYNYQALEFLPRERASDPSAEEVPXKISTWNT 472
G E Q+G A+ + + R K I+L + L A DP E + ++ T T
Sbjct: 59 GTEKQIGEAIKESGVPR--KDIFLTSKTLFGLL----ADDP-IESISNQLKTLQT 106
>UniRef50_Q7G764 Cluster: Probable NAD(P)H-dependent oxidoreductase
1; n=32; Eukaryota|Rep: Probable NAD(P)H-dependent
oxidoreductase 1 - Oryza sativa subsp. japonica (Rice)
Length = 321
Score = 51.2 bits (117), Expect = 4e-05
Identities = 31/114 (27%), Positives = 59/114 (51%), Gaps = 9/114 (7%)
Frame = +3
Query: 366 RESIFITTKLWNSYHEREQVIPALRKSLXK------SQLGIRRPVFDSLAHSY---V*ER 518
R +F+T+K+W S +V+PA R++L L + PV +Y +
Sbjct: 77 RADVFVTSKIWCSDLHAGRVVPAARETLRNLGMDYVDLLLVHWPV-SLTPGNYDFPFPKE 135
Query: 519 YLARHVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGLEKPSALQIE 680
+ D WRGM + +LGL ++IG+SNF+ +++++++ +P+ Q+E
Sbjct: 136 VILPSFDMEGVWRGMEECHRLGLARAIGVSNFSAKKLEQLLSLAAVRPAVNQVE 189
Score = 37.5 bits (83), Expect = 0.53
Identities = 17/41 (41%), Positives = 24/41 (58%)
Frame = +2
Query: 233 TNDTEQAVIYALEAGYTHIDTAYKYGIEDQVGRALXQEILR 355
+ DT A++ A+E GY H DTA Y E VG A+ + + R
Sbjct: 31 SEDTTAAMLRAIELGYRHFDTARIYATEGCVGEAVAEAVRR 71
Score = 34.7 bits (76), Expect = 3.7
Identities = 11/20 (55%), Positives = 17/20 (85%)
Frame = +1
Query: 448 LXNLNLEYVDLYLIHWPIAM 507
L NL ++YVDL L+HWP+++
Sbjct: 104 LRNLGMDYVDLLLVHWPVSL 123
>UniRef50_Q9FJK0 Cluster: Aldose reductase-like protein; n=3; core
eudicotyledons|Rep: Aldose reductase-like protein -
Arabidopsis thaliana (Mouse-ear cress)
Length = 316
Score = 50.8 bits (116), Expect = 5e-05
Identities = 30/113 (26%), Positives = 60/113 (53%), Gaps = 6/113 (5%)
Frame = +3
Query: 360 LKRESIFITTKLWNS-YHEREQVIPALRKSLXKSQLG---IRRPVF--DSLAHSYV*ERY 521
++R+ +F+T+KLW+S +H+ + K++ L + P+ ++ E
Sbjct: 71 VQRDDLFVTSKLWSSDHHDPISALIQTLKTMGLDYLDNYLVHWPIKLKPGVSEPIPKEDE 130
Query: 522 LARHVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGLEKPSALQIE 680
+ + +TW+GM ++GL +SIG+SNF+ ++I ++D PS Q+E
Sbjct: 131 FEKDLGIEETWQGMERCLEMGLCRSIGVSNFSSKKIFDLLDFASVSPSVNQVE 183
Score = 41.9 bits (94), Expect = 0.024
Identities = 27/78 (34%), Positives = 40/78 (51%)
Frame = +2
Query: 149 QLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQVG 328
+L G IP++ +GT+ + + T AV A++ GY H DTA YG E+ +G
Sbjct: 7 RLRCGETIPLLGMGTYCPQKDR-------ESTISAVHQAIKIGYRHFDTAKIYGSEEALG 59
Query: 329 RALXQEILRRT*KRIYLY 382
AL Q I T +R L+
Sbjct: 60 TALGQAISYGTVQRDDLF 77
>UniRef50_Q5KI95 Cluster: Aldo-keto reductase, putative; n=14;
Dikarya|Rep: Aldo-keto reductase, putative -
Cryptococcus neoformans (Filobasidiella neoformans)
Length = 353
Score = 50.8 bits (116), Expect = 5e-05
Identities = 41/119 (34%), Positives = 56/119 (47%), Gaps = 11/119 (9%)
Frame = +3
Query: 357 GLKRESIFITTKLWNSYHER-EQVIPALRKSLXKSQLG---IRRPV--FDSLAHSYV--- 509
G+ R IF+T+K+W+SYH+R E+ + KSL L I PV + H
Sbjct: 97 GVPRSEIFLTSKVWSSYHDRVEECLDTTLKSLQTDYLDLYLIHWPVRLAPNGTHPLFPVK 156
Query: 510 --*ERYLARHVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGLEKPSALQIE 680
R L D TW M D K G K+IG+SN I+ II +G P+ Q+E
Sbjct: 157 PDGSRNLDWDWDQAKTWAQMEDVLKKGKAKAIGLSNAGIPIIEHIIKTGKVTPAVNQVE 215
Score = 50.0 bits (114), Expect = 9e-05
Identities = 31/72 (43%), Positives = 42/72 (58%), Gaps = 1/72 (1%)
Frame = +2
Query: 116 FTSADLIVPT-LQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHID 292
F S + PT +L++G +IP + LGTW + K +V QAV +AL+AGY HID
Sbjct: 28 FNSLIMSAPTSFKLNTGASIPAIGLGTW-----QAKAGEV----RQAVAHALKAGYRHID 78
Query: 293 TAYKYGIEDQVG 328
A Y ED+VG
Sbjct: 79 GALCYQNEDEVG 90
Score = 35.9 bits (79), Expect = 1.6
Identities = 13/25 (52%), Positives = 18/25 (72%)
Frame = +1
Query: 448 LXNLNLEYVDLYLIHWPIAMFENDT 522
L +L +Y+DLYLIHWP+ + N T
Sbjct: 125 LKSLQTDYLDLYLIHWPVRLAPNGT 149
>UniRef50_Q4PAT5 Cluster: Putative uncharacterized protein; n=1;
Ustilago maydis|Rep: Putative uncharacterized protein -
Ustilago maydis (Smut fungus)
Length = 700
Score = 50.8 bits (116), Expect = 5e-05
Identities = 39/126 (30%), Positives = 57/126 (45%), Gaps = 18/126 (14%)
Frame = +3
Query: 357 GLKRESIFITTKLWNSYHEREQVIPALRKSLXK------------------SQLGIRRPV 482
G+ R +++T+KLWNS+H E V AL SL + G P
Sbjct: 70 GVPRSQLWLTSKLWNSFHHPEHVEKALDASLKDLGTDYLDLYLMHWPVAFLNSKGSMVPS 129
Query: 483 FDSLAHSYV*ERYLARHVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGLEKP 662
S V L+R DF+ T+R M + K G ++IG+SNFN + ++D KP
Sbjct: 130 IRSTGGHPVESEDLSR--DFMATYRVMEEMVKKGKVRNIGVSNFNIRRTSEVVDEASIKP 187
Query: 663 SALQIE 680
Q+E
Sbjct: 188 VVNQVE 193
Score = 37.1 bits (82), Expect = 0.70
Identities = 23/62 (37%), Positives = 31/62 (50%)
Frame = +2
Query: 152 LSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQVGR 331
L++G IP + GTW K Q T AV +A++ GY HID A+ Y ED V
Sbjct: 14 LANGAQIPKLGFGTW-----KMSKEQAT----PAVAHAIKTGYRHIDCAWAYRNEDAVAA 64
Query: 332 AL 337
+
Sbjct: 65 GI 66
Score = 33.5 bits (73), Expect = 8.6
Identities = 11/23 (47%), Positives = 17/23 (73%)
Frame = +1
Query: 448 LXNLNLEYVDLYLIHWPIAMFEN 516
L +L +Y+DLYL+HWP+A +
Sbjct: 100 LKDLGTDYLDLYLMHWPVAFLNS 122
>UniRef50_Q890A0 Cluster: Oxidoreductase; n=6; Lactobacillales|Rep:
Oxidoreductase - Lactobacillus plantarum
Length = 282
Score = 50.4 bits (115), Expect = 7e-05
Identities = 32/63 (50%), Positives = 37/63 (58%)
Frame = +2
Query: 149 QLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQVG 328
QL++G NIP VA GTW P G+ T QAV AL AGY HIDTA Y E VG
Sbjct: 9 QLANGVNIPKVAFGTW--QIPGGEA------TYQAVRAALAAGYRHIDTALAYQNEASVG 60
Query: 329 RAL 337
+A+
Sbjct: 61 QAI 63
Score = 37.9 bits (84), Expect = 0.40
Identities = 33/110 (30%), Positives = 50/110 (45%), Gaps = 2/110 (1%)
Frame = +3
Query: 357 GLKRESIFITTKLWNSYHEREQVIPALRKSLXKSQLGIRRPVFDSLAHSYV*ERYLARHV 536
G+ RE IF+TTKL + + +SL LG+ V L H+ + R
Sbjct: 67 GIPREQIFVTTKLPAETKSYQGALNDFDRSL--KNLGLDY-VDLYLVHAPWPWGQVGRVY 123
Query: 537 DF--LDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGLEKPSALQIE 680
D LD W+ M + G K+IG+SNF ++ I++ P QI+
Sbjct: 124 DEANLDVWQAMEAIYQSGRAKAIGVSNFAVRDLKNILNQATIPPMVNQIQ 173
>UniRef50_Q5FK99 Cluster: Oxidoreductase aldo-keto reductase family;
n=5; Lactobacillus|Rep: Oxidoreductase aldo-keto
reductase family - Lactobacillus acidophilus
Length = 289
Score = 50.4 bits (115), Expect = 7e-05
Identities = 37/107 (34%), Positives = 53/107 (49%)
Frame = +3
Query: 360 LKRESIFITTKLWNSYHEREQVIPALRKSLXKSQLGIRRPVFDSLAHSYV*ERYLARHVD 539
+ R+ IF+TTKLW S E+ A+ + L +LG D + + + Y D
Sbjct: 67 VNRDDIFLTTKLWVSNFTYEKASKAIDEDL--KELGT-----DYIDMMLLHQAY----GD 115
Query: 540 FLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGLEKPSALQIE 680
WR + DA+K G TKSIG+SNF +Q+ + KP QIE
Sbjct: 116 VAGAWRALEDAQKAGKTKSIGVSNFWPDQLMNLQLMSNVKPVVNQIE 162
Score = 33.5 bits (73), Expect = 8.6
Identities = 24/76 (31%), Positives = 36/76 (47%), Gaps = 2/76 (2%)
Frame = +2
Query: 137 VPTLQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTE--QAVIYALEAGYTHIDTAYKYG 310
+P ++L+ G IP + G V Q++N E +AV A+ GY IDTA Y
Sbjct: 4 IPKIKLNDGNEIPQLGFG----------VFQISNHDEAVKAVESAISNGYRLIDTAEAYN 53
Query: 311 IEDQVGRALXQEILRR 358
+ VG A+ + R
Sbjct: 54 NQTAVGEAIKNSDVNR 69
>UniRef50_Q24C22 Cluster: Oxidoreductase, aldo/keto reductase family
protein; n=4; Oligohymenophorea|Rep: Oxidoreductase,
aldo/keto reductase family protein - Tetrahymena
thermophila SB210
Length = 297
Score = 50.4 bits (115), Expect = 7e-05
Identities = 32/109 (29%), Positives = 52/109 (47%), Gaps = 1/109 (0%)
Frame = +3
Query: 357 GLKRESIFITTKLWNSYHEREQVIPALRKSLXKSQLGIRRPVFDSLAHSYV*ERYLARHV 536
G+KRE +FIT+K+ EQ A++ L + + V ++
Sbjct: 76 GIKREDLFITSKISPGEQGYEQAKKAVQDMLTRLNIKYLDCVLIHWPGVSKLPPNDPKNA 135
Query: 537 DF-LDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGLEKPSALQIE 680
L+TW+ +I+ +K G+ K IG+SNFN +Q +I+ KP Q E
Sbjct: 136 QIRLETWKALIELRKAGVIKHIGVSNFNINHLQHLIEKSEFKPEMNQFE 184
Score = 39.1 bits (87), Expect = 0.17
Identities = 25/67 (37%), Positives = 34/67 (50%)
Frame = +2
Query: 137 VPTLQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIE 316
VP L GG+IP + GT+ ++ Q ND V AL+ GYTHIDTA Y E
Sbjct: 13 VPILNFREGGSIPQIGYGTY-------ELRQ--NDCIIGVTEALKIGYTHIDTASVYRNE 63
Query: 317 DQVGRAL 337
+ + +
Sbjct: 64 QDIAKVI 70
>UniRef50_UPI000155CAC7 Cluster: PREDICTED: hypothetical protein;
n=1; Ornithorhynchus anatinus|Rep: PREDICTED:
hypothetical protein - Ornithorhynchus anatinus
Length = 419
Score = 50.0 bits (114), Expect = 9e-05
Identities = 33/77 (42%), Positives = 46/77 (59%), Gaps = 1/77 (1%)
Frame = +2
Query: 131 LIVPTLQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYAL-EAGYTHIDTAYKY 307
L VPT+ L++G NIP++ LGT H V + AVIYAL E G HIDTA +Y
Sbjct: 10 LPVPTVPLANGLNIPILGLGT--SH--------VGGYSHDAVIYALKECGIRHIDTAKRY 59
Query: 308 GIEDQVGRALXQEILRR 358
G E +G+A+ + ++R
Sbjct: 60 GCELLLGKAIQESGVKR 76
>UniRef50_Q0SFM4 Cluster: Probable 2,5-didehydrogluconate reductase;
n=1; Rhodococcus sp. RHA1|Rep: Probable
2,5-didehydrogluconate reductase - Rhodococcus sp.
(strain RHA1)
Length = 265
Score = 50.0 bits (114), Expect = 9e-05
Identities = 31/108 (28%), Positives = 55/108 (50%)
Frame = +3
Query: 357 GLKRESIFITTKLWNSYHEREQVIPALRKSLXKSQLGIRRPVFDSLAHSYV*ERYLARHV 536
G+ RE +F+TTKL S H + A+ +SL LG+ R ++ L RH
Sbjct: 54 GVPREELFVTTKLRGSDHVSGDIRGAVERSL--KNLGLDR------LDLFLIHWPLPRHN 105
Query: 537 DFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGLEKPSALQIE 680
++ + M+ + GL + +G+SNF + ++R++ E P+ QI+
Sbjct: 106 RYVAAFEAMLACRDAGLVRHVGVSNFLETHLRRVVAETGESPAVNQIQ 153
Score = 37.5 bits (83), Expect = 0.53
Identities = 25/59 (42%), Positives = 31/59 (52%)
Frame = +2
Query: 167 NIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQVGRALXQ 343
+IP + LGTW P D +AV+ +EAGY IDTA Y ED VG AL +
Sbjct: 3 DIPPLGLGTWPLTGP---------DATRAVLSGIEAGYRLIDTATIYDNEDAVGVALAE 52
>UniRef50_A2UAH0 Cluster: Aldo/keto reductase; n=1; Bacillus
coagulans 36D1|Rep: Aldo/keto reductase - Bacillus
coagulans 36D1
Length = 273
Score = 50.0 bits (114), Expect = 9e-05
Identities = 29/65 (44%), Positives = 37/65 (56%)
Frame = +2
Query: 143 TLQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQ 322
T L +G IP + LGTW P G+ T AV +AL+ GY HIDTAY Y E+
Sbjct: 7 TFVLENGVAIPKIGLGTW--QVPNGET------TYHAVSFALKNGYRHIDTAYAYHNEES 58
Query: 323 VGRAL 337
VG+A+
Sbjct: 59 VGKAV 63
>UniRef50_A0JRJ3 Cluster: 2,5-didehydrogluconate reductase; n=3;
Actinobacteria (class)|Rep: 2,5-didehydrogluconate
reductase - Arthrobacter sp. (strain FB24)
Length = 276
Score = 50.0 bits (114), Expect = 9e-05
Identities = 33/94 (35%), Positives = 47/94 (50%)
Frame = +2
Query: 140 PTLQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIED 319
P ++L+ G IP + LGTW P + AV+ A+E GY HIDTA KYG E
Sbjct: 5 PVIELNDGHRIPQIGLGTW----PLDD-----HQVAAAVVNAVEGGYRHIDTAVKYGNEK 55
Query: 320 QVGRALXQEILRRT*KRIYLYNYQALEFLPRERA 421
VG + L R+ +++ EF ++RA
Sbjct: 56 GVGNGIRSSGLDRS--ELFITTKLDGEFQGQDRA 87
Score = 46.0 bits (104), Expect = 0.002
Identities = 33/110 (30%), Positives = 55/110 (50%)
Frame = +3
Query: 351 SEGLKRESIFITTKLWNSYHEREQVIPALRKSLXKSQLGIRRPVFDSLAHSYV*ERYLAR 530
S GL R +FITTKL + +++ + L SL + LG+ D L + L R
Sbjct: 63 SSGLDRSELFITTKLDGEFQGQDRAVAGLDGSLKR--LGL--DYVDLLLIHWP----LPR 114
Query: 531 HVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGLEKPSALQIE 680
+F+ TW+ + G +SIG+SNF ++R++ + P+ QI+
Sbjct: 115 RDEFISTWKTFERLQADGKVRSIGVSNFKPAHLERLMAACDVVPAVNQIQ 164
>UniRef50_A2EYY6 Cluster: Oxidoreductase, aldo/keto reductase family
protein; n=9; Trichomonas vaginalis G3|Rep:
Oxidoreductase, aldo/keto reductase family protein -
Trichomonas vaginalis G3
Length = 308
Score = 50.0 bits (114), Expect = 9e-05
Identities = 36/111 (32%), Positives = 59/111 (53%), Gaps = 14/111 (12%)
Frame = +3
Query: 348 FSEGLKRESIFITTKLWNSYHEREQVIPALRKSLXKSQLG------IRRP-VFDSL---- 494
+ G+KRE+I+IT+KLWN++H E V A RK+L +L + P F +
Sbjct: 56 WDSGIKRENIWITSKLWNTHHRLEIVEEACRKTLKDLRLDYLDLYLMHYPFAFQNTGIGG 115
Query: 495 AHSYV*ER---YLARHVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRI 638
+ + + E+ V +DTW+ M + GL K IG+SN+ Q++R+
Sbjct: 116 SLNPLDEKGNTIFDDGVSLIDTWKAMEKLVEKGLVKRIGVSNWTINQLERL 166
Score = 44.4 bits (100), Expect = 0.005
Identities = 27/59 (45%), Positives = 32/59 (54%), Gaps = 1/59 (1%)
Frame = +2
Query: 170 IPVVALGTWLGHRPKGKVVQVTNDTEQAVIYAL-EAGYTHIDTAYKYGIEDQVGRALXQ 343
IP + LGTW R + D A+ YA+ EAGY HID A Y ED VG+AL Q
Sbjct: 4 IPTIGLGTWKSPR--------SEDLVNAITYAIKEAGYVHIDCALCYENEDIVGQALQQ 54
>UniRef50_UPI0000E45E29 Cluster: PREDICTED: similar to aldose
reductase; n=1; Strongylocentrotus purpuratus|Rep:
PREDICTED: similar to aldose reductase -
Strongylocentrotus purpuratus
Length = 274
Score = 49.6 bits (113), Expect = 1e-04
Identities = 36/107 (33%), Positives = 57/107 (53%)
Frame = +3
Query: 360 LKRESIFITTKLWNSYHEREQVIPALRKSLXKSQLGIRRPVFDSLAHSYV*ERYLARHVD 539
+KRE IFIT+KLWN+ H + V A +L QL SYV + YL +
Sbjct: 52 VKREDIFITSKLWNNKHHPDDVEQACDITLKNLQL------------SYV-DLYL---MH 95
Query: 540 FLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGLEKPSALQIE 680
+ ++ M G K+IG+SNF+ + ++R+I+ +P+ LQ+E
Sbjct: 96 WPMAYQAMEKLVTSGKCKAIGLSNFSMKMMKRVIEKATIQPANLQVE 142
Score = 36.7 bits (81), Expect = 0.92
Identities = 14/19 (73%), Positives = 16/19 (84%)
Frame = +1
Query: 448 LXNLNLEYVDLYLIHWPIA 504
L NL L YVDLYL+HWP+A
Sbjct: 81 LKNLQLSYVDLYLMHWPMA 99
Score = 35.9 bits (79), Expect = 1.6
Identities = 18/42 (42%), Positives = 24/42 (57%)
Frame = +2
Query: 245 EQAVIYALEAGYTHIDTAYKYGIEDQVGRALXQEILRRT*KR 370
E AV A++ GY HID A+ YG E +VG L ++ KR
Sbjct: 13 EAAVKAAIDCGYRHIDCAHVYGNEAEVGAGLKEKFDANVVKR 54
>UniRef50_Q4JX70 Cluster: Putative oxidoreductase; n=1;
Corynebacterium jeikeium K411|Rep: Putative
oxidoreductase - Corynebacterium jeikeium (strain K411)
Length = 285
Score = 49.6 bits (113), Expect = 1e-04
Identities = 29/72 (40%), Positives = 41/72 (56%), Gaps = 1/72 (1%)
Frame = +2
Query: 137 VPTLQLSSGGNIPVVALGTWLGHRPKGKVVQVTN-DTEQAVIYALEAGYTHIDTAYKYGI 313
VPTL+++ G P + LG W Q+++ DT +V A+E GY HIDTA YG
Sbjct: 8 VPTLEMNDGKTTPQLGLGVW----------QLSDEDTYTSVRAAIETGYRHIDTAAIYGN 57
Query: 314 EDQVGRALXQEI 349
E+ VGRA+ +
Sbjct: 58 EEAVGRAVADAV 69
>UniRef50_A6RKL9 Cluster: Putative uncharacterized protein; n=3;
Sclerotiniaceae|Rep: Putative uncharacterized protein -
Botryotinia fuckeliana B05.10
Length = 360
Score = 49.6 bits (113), Expect = 1e-04
Identities = 31/99 (31%), Positives = 53/99 (53%), Gaps = 1/99 (1%)
Frame = +3
Query: 357 GLKRESIFITTKLWNSYH-EREQVIPALRKSLXKSQLGIRRPVFDSLAHSYV*ERYLARH 533
GLKRE I++T+KLWN +H E V L ++L LG+ + A++
Sbjct: 95 GLKREDIWVTSKLWNDHHGSYENVEKGLNQTL--QDLGLEYLDLYLIHWPIGFSSNGAKN 152
Query: 534 VDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSG 650
+D + T++ MI K +IG+SNF+ Q++ ++ +G
Sbjct: 153 LDHVQTYKSMISLPK-SRVLNIGVSNFSPLQLKNVVSTG 190
Score = 41.5 bits (93), Expect = 0.032
Identities = 27/66 (40%), Positives = 33/66 (50%)
Frame = +2
Query: 173 PVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQVGRALXQEIL 352
P++ GTW V N TE AV YA+E GY ID A YG E VGR + + +
Sbjct: 40 PLIGFGTW------NLKVSPENTTE-AVAYAIEIGYRQIDCAAVYGNEVAVGRGIEEGLK 92
Query: 353 RRT*KR 370
R KR
Sbjct: 93 RAGLKR 98
Score = 37.9 bits (84), Expect = 0.40
Identities = 15/23 (65%), Positives = 17/23 (73%)
Frame = +1
Query: 448 LXNLNLEYVDLYLIHWPIAMFEN 516
L +L LEY+DLYLIHWPI N
Sbjct: 126 LQDLGLEYLDLYLIHWPIGFSSN 148
>UniRef50_A2QBD7 Cluster: Catalytic activity: an alcohol + NADP(+)
<=> an aldehyde + NADPH; n=4; Trichocomaceae|Rep:
Catalytic activity: an alcohol + NADP(+) <=> an aldehyde
+ NADPH - Aspergillus niger
Length = 323
Score = 49.6 bits (113), Expect = 1e-04
Identities = 35/118 (29%), Positives = 56/118 (47%), Gaps = 10/118 (8%)
Frame = +3
Query: 357 GLKRESIFITTKLWNSYHEREQVIPALRKSLXKSQLG------IRRPVFDSLAHSYV*ER 518
G+ RE IFIT KLWN+ H E V PAL K+L + + P +
Sbjct: 65 GVPREEIFITGKLWNTKHAPEDVEPALDKTLQDLGVAYLDLYLMHWPCAFKGGDKWFPLN 124
Query: 519 ----YLARHVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGLEKPSALQIE 680
+ ++D++ T+R M G ++IG+SNFN +++ ++ P+ QIE
Sbjct: 125 DDGVFDLANIDYITTYRAMEKLLATGKVRAIGVSNFNIRRLEELLGQVSVVPAVNQIE 182
Score = 38.7 bits (86), Expect = 0.23
Identities = 24/62 (38%), Positives = 32/62 (51%)
Frame = +2
Query: 152 LSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQVGR 331
+++G IP V GTW + K ++V N AV AL GY HID A Y E +VG
Sbjct: 9 INTGAKIPAVGFGTW-----QAKPLEVEN----AVEVALREGYRHIDCAAIYRNETEVGN 59
Query: 332 AL 337
+
Sbjct: 60 GI 61
>UniRef50_A1D4E3 Cluster: D-xylose reductase (Xyl1), putative; n=5;
Pezizomycotina|Rep: D-xylose reductase (Xyl1), putative
- Neosartorya fischeri (strain ATCC 1020 / DSM 3700 /
NRRL 181)(Aspergillus fischerianus (strain ATCC 1020 /
DSM 3700 / NRRL 181))
Length = 321
Score = 49.6 bits (113), Expect = 1e-04
Identities = 41/129 (31%), Positives = 62/129 (48%), Gaps = 16/129 (12%)
Frame = +3
Query: 342 KKFSEGL-KRESIFITTKLWNSYHEREQVIPALRKSLXKSQLGI--RRPVFDSLAHSYV* 512
+ EG+ KRE +FI +KLWNS+H+ ++V P RK L L V +A YV
Sbjct: 62 RAIQEGIVKREDLFIVSKLWNSFHDGDRVEPICRKQLADWGLDYFDLFIVHFPIALKYVD 121
Query: 513 E--RY----LAR-------HVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGL 653
RY L+ + +TW M L +SIG+SNF+ + + ++
Sbjct: 122 PAVRYPPGWLSENNKLEFSNASIQETWTAMESLVDKKLARSIGVSNFSAQLLMDLLRYAR 181
Query: 654 EKPSALQIE 680
+P+ LQIE
Sbjct: 182 IRPATLQIE 190
Score = 37.9 bits (84), Expect = 0.40
Identities = 27/85 (31%), Positives = 43/85 (50%), Gaps = 1/85 (1%)
Frame = +2
Query: 131 LIVPTLQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIY-ALEAGYTHIDTAYKY 307
+ P+ +L+SG ++P+V G W +V N+T IY A++AGY D A Y
Sbjct: 1 MTTPSTKLNSGYDMPLVGFGLW----------KVNNETCADQIYHAIKAGYRLFDGACDY 50
Query: 308 GIEDQVGRALXQEILRRT*KRIYLY 382
G E + G+ + + I KR L+
Sbjct: 51 GNEVEAGKGVARAIQEGIVKREDLF 75
>UniRef50_Q6F7K7 Cluster: 2,5-diketo-D-gluconate reductase; n=20;
Bacteria|Rep: 2,5-diketo-D-gluconate reductase -
Acinetobacter sp. (strain ADP1)
Length = 297
Score = 49.2 bits (112), Expect = 2e-04
Identities = 30/94 (31%), Positives = 52/94 (55%)
Frame = +3
Query: 357 GLKRESIFITTKLWNSYHEREQVIPALRKSLXKSQLGIRRPVFDSLAHSYV*ERYLARHV 536
GL R+ IFIT+KL +H ++ + + +SL + Q FD L Y+ +
Sbjct: 83 GLLRDEIFITSKLPGRHHAYDKAMETIEESLYRMQ-------FDYL-DLYLIHWPNPQQG 134
Query: 537 DFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRI 638
+++ W+ +IDA+K G +SIG+SNF + I+ +
Sbjct: 135 LYIEAWQALIDAQKKGYIRSIGVSNFLPKHIETL 168
>UniRef50_Q1YPE5 Cluster: Aldehyde reductase; n=7; Bacteria|Rep:
Aldehyde reductase - gamma proteobacterium HTCC2207
Length = 330
Score = 49.2 bits (112), Expect = 2e-04
Identities = 42/133 (31%), Positives = 61/133 (45%), Gaps = 20/133 (15%)
Frame = +3
Query: 342 KKFSEGL-KRESIFITTKLWNSYHEREQVIPALRKSLXKSQLGI--RRPVFDSLAHSYV- 509
+ +EGL RE ++ITTKLWN+YH E V A R+S+ L V +A YV
Sbjct: 65 RAIAEGLCSREELWITTKLWNTYHRAEHVEAACRRSMDDLGLDYIDLYLVHFPIALRYVD 124
Query: 510 -*ERYLAR---------------HVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRII 641
+RY A V +TW M + GL + IG+ N++ + ++
Sbjct: 125 FNDRYPAEWIFDHSAEDPAMELDQVPLSETWGAMEQLVESGLVRQIGVCNYSAVLLHDLM 184
Query: 642 DSGLEKPSALQIE 680
KP+ LQIE
Sbjct: 185 SYARIKPAMLQIE 197
Score = 44.0 bits (99), Expect = 0.006
Identities = 27/71 (38%), Positives = 40/71 (56%)
Frame = +2
Query: 137 VPTLQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIE 316
VP +++SS ++P V LG W K+ Q + QAV A++ GY H+D+A YG E
Sbjct: 7 VPGVKVSSK-SMPAVGLGLW-------KITQ--DSAAQAVYEAIKVGYRHLDSAADYGNE 56
Query: 317 DQVGRALXQEI 349
QVG + + I
Sbjct: 57 QQVGEGIARAI 67
>UniRef50_Q9USV2 Cluster: Xylose and arabinose reductase; n=2;
Schizosaccharomyces pombe|Rep: Xylose and arabinose
reductase - Schizosaccharomyces pombe (Fission yeast)
Length = 276
Score = 49.2 bits (112), Expect = 2e-04
Identities = 34/108 (31%), Positives = 57/108 (52%), Gaps = 1/108 (0%)
Frame = +3
Query: 360 LKRESIFITTKLWNSYHEREQVIPALRKSLXKSQLGIRRPVFDS-LAHSYV*ERYLARHV 536
+KRE I + TK+ +S E+ A+ +SL ++ RP D L HS ++ R +
Sbjct: 67 IKREDITLITKIPDSLQGFERTWKAVEQSLRRTG----RPKLDVVLIHS---PKWPVRRI 119
Query: 537 DFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGLEKPSALQIE 680
+ +WR ++ +K G IG+SN+N ++ II GL P+ Q+E
Sbjct: 120 E---SWRALLQHQKEGRINKIGVSNYNIHHLEEIISLGLPLPAINQVE 164
>UniRef50_P22045 Cluster: Probable reductase; n=101; cellular
organisms|Rep: Probable reductase - Leishmania major
Length = 284
Score = 49.2 bits (112), Expect = 2e-04
Identities = 32/111 (28%), Positives = 56/111 (50%), Gaps = 1/111 (0%)
Frame = +3
Query: 351 SEGLKRESIFITTKLWNSYHEREQVIPALRKSLXKSQLGIRRPVFDSLAHSYV*ERYLAR 530
+ G+ RE +FITTKLWN+ E + A +S + +LG+ + L H + L++
Sbjct: 66 ASGVPREDVFITTKLWNTEQGYESTLAAFEES--RQKLGVDY-IDLYLIHWPRGKDILSK 122
Query: 531 H-VDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGLEKPSALQIE 680
+LD+WR K ++IG+SNF+ ++ ++ P Q+E
Sbjct: 123 EGKKYLDSWRAFEQLYKEKKVRAIGVSNFHIHHLEDVLAMCTVTPMVNQVE 173
Score = 44.8 bits (101), Expect = 0.003
Identities = 29/62 (46%), Positives = 34/62 (54%)
Frame = +2
Query: 152 LSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQVGR 331
LS+G +P LG W P G+V TE AV +AL AGY HIDTA Y E+ VG
Sbjct: 11 LSNGVKMPQFGLGVW--QSPAGEV------TENAVNWALCAGYRHIDTAAIYKNEESVGA 62
Query: 332 AL 337
L
Sbjct: 63 GL 64
>UniRef50_Q8F1G4 Cluster: Aldehyde reductase; n=8; Bacteria|Rep:
Aldehyde reductase - Leptospira interrogans
Length = 278
Score = 48.8 bits (111), Expect = 2e-04
Identities = 30/79 (37%), Positives = 47/79 (59%)
Frame = +2
Query: 143 TLQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQ 322
T+ L++G ++P++ LG W GK + ++AV+ ALEAGY HIDTA Y E
Sbjct: 11 TIMLNNGISMPILGLGVW--KTKSGK------ECKEAVLNALEAGYRHIDTARIYDNEVD 62
Query: 323 VGRALXQEILRRT*KRIYL 379
VG+A+ + + R K I++
Sbjct: 63 VGQAIRESGIPR--KEIFI 79
Score = 40.7 bits (91), Expect = 0.056
Identities = 33/108 (30%), Positives = 53/108 (49%)
Frame = +3
Query: 357 GLKRESIFITTKLWNSYHEREQVIPALRKSLXKSQLGIRRPVFDSLAHSYV*ERYLARHV 536
G+ R+ IFITTKLWN+ ++ AL SL +LGI V L H V +
Sbjct: 71 GIPRKEIFITTKLWNADQGSDKTRKALENSL--DRLGIDF-VDLYLIHFPVTSKR----- 122
Query: 537 DFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGLEKPSALQIE 680
+D+W+ + L K+IG+SN+ + ++ + P+ Q+E
Sbjct: 123 --MDSWKELEKLYHDKLCKAIGVSNYTIIHLTELLKNSQITPAVNQVE 168
>UniRef50_Q8ET73 Cluster: 2,5-diketo-D-gluconate reductase; n=12;
Bacteria|Rep: 2,5-diketo-D-gluconate reductase -
Oceanobacillus iheyensis
Length = 280
Score = 48.8 bits (111), Expect = 2e-04
Identities = 30/105 (28%), Positives = 55/105 (52%)
Frame = +3
Query: 366 RESIFITTKLWNSYHEREQVIPALRKSLXKSQLGIRRPVFDSLAHSYV*ERYLARHVDFL 545
RE + IT+KL YH ++ + +++SL ++ L +D Y+ ++
Sbjct: 69 REQLLITSKLPGRYHHYDKAVTTIQESLYRANLDY----YDL----YLIHWPNPIQDIYV 120
Query: 546 DTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGLEKPSALQIE 680
+ W+ +I+AK+ G +SIG+ NF E ++R+ E P+ QIE
Sbjct: 121 EAWQALIEAKRRGYIRSIGVCNFLPEHLERLKQETGELPTINQIE 165
Score = 39.9 bits (89), Expect = 0.099
Identities = 27/67 (40%), Positives = 34/67 (50%)
Frame = +2
Query: 137 VPTLQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIE 316
+P + L G IP V GT+ R G ND QA+ A++ GY IDTAY Y E
Sbjct: 5 IPNVTLHDGLTIPKVGFGTY---RLNG------NDGVQAINNAIDHGYRLIDTAYNYENE 55
Query: 317 DQVGRAL 337
VG A+
Sbjct: 56 GTVGEAV 62
Score = 33.5 bits (73), Expect = 8.6
Identities = 14/30 (46%), Positives = 18/30 (60%)
Frame = +1
Query: 448 LXNLNLEYVDLYLIHWPIAMFENDTLLDTW 537
L NL+Y DLYLIHWP + D ++ W
Sbjct: 96 LYRANLDYYDLYLIHWPNPI--QDIYVEAW 123
>UniRef50_Q2V420 Cluster: Uncharacterized protein At2g37770.1; n=1;
Arabidopsis thaliana|Rep: Uncharacterized protein
At2g37770.1 - Arabidopsis thaliana (Mouse-ear cress)
Length = 283
Score = 48.8 bits (111), Expect = 2e-04
Identities = 37/125 (29%), Positives = 59/125 (47%), Gaps = 8/125 (6%)
Frame = +3
Query: 330 GPXTKKFSEG--LKRESIFITTKLWNSYHEREQVIPALRKSLXKSQLG------IRRPVF 485
G KK E +KRE +FIT+KLW + H+ + V AL ++L QL I P
Sbjct: 59 GAVLKKLFEDRVVKREDLFITSKLWCTDHDPQDVPEALNRTLKDLQLEYVDLYLIHWPAR 118
Query: 486 DSLAHSYV*ERYLARHVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGLEKPS 665
+ L VD TW+ M G ++IG+SNF+ +++ +++ P+
Sbjct: 119 IKKGSVGIKPENLL-PVDIPSTWKAMEALYDSGKARAIGVSNFSTKKLADLLELARVPPA 177
Query: 666 ALQIE 680
Q+E
Sbjct: 178 VNQVE 182
Score = 38.7 bits (86), Expect = 0.23
Identities = 28/78 (35%), Positives = 37/78 (47%)
Frame = +2
Query: 149 QLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQVG 328
+L++G P V LGTW G V AV A++ GY HID A YG E ++G
Sbjct: 9 KLNTGAKFPSVGLGTW--QASPGLV-------GDAVAAAVKIGYRHIDCAQIYGNEKEIG 59
Query: 329 RALXQEILRRT*KRIYLY 382
L + R KR L+
Sbjct: 60 AVLKKLFEDRVVKREDLF 77
Score = 35.9 bits (79), Expect = 1.6
Identities = 14/17 (82%), Positives = 15/17 (88%)
Frame = +1
Query: 448 LXNLNLEYVDLYLIHWP 498
L +L LEYVDLYLIHWP
Sbjct: 100 LKDLQLEYVDLYLIHWP 116
>UniRef50_Q0PGJ6 Cluster: Aldo-keto reductase; n=32;
Magnoliophyta|Rep: Aldo-keto reductase - Arabidopsis
thaliana (Mouse-ear cress)
Length = 315
Score = 48.8 bits (111), Expect = 2e-04
Identities = 37/125 (29%), Positives = 59/125 (47%), Gaps = 8/125 (6%)
Frame = +3
Query: 330 GPXTKKFSEG--LKRESIFITTKLWNSYHEREQVIPALRKSLXKSQLG------IRRPVF 485
G KK E +KRE +FIT+KLW + H+ + V AL ++L QL I P
Sbjct: 59 GAVLKKLFEDRVVKREDLFITSKLWCTDHDPQDVPEALNRTLKDLQLEYVDLYLIHWPAR 118
Query: 486 DSLAHSYV*ERYLARHVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGLEKPS 665
+ L VD TW+ M G ++IG+SNF+ +++ +++ P+
Sbjct: 119 IKKGSVGIKPENLL-PVDIPSTWKAMEALYDSGKARAIGVSNFSTKKLADLLELARVPPA 177
Query: 666 ALQIE 680
Q+E
Sbjct: 178 VNQVE 182
Score = 38.7 bits (86), Expect = 0.23
Identities = 28/78 (35%), Positives = 37/78 (47%)
Frame = +2
Query: 149 QLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQVG 328
+L++G P V LGTW G V AV A++ GY HID A YG E ++G
Sbjct: 9 KLNTGAKFPSVGLGTW--QASPGLV-------GDAVAAAVKIGYRHIDCAQIYGNEKEIG 59
Query: 329 RALXQEILRRT*KRIYLY 382
L + R KR L+
Sbjct: 60 AVLKKLFEDRVVKREDLF 77
Score = 35.9 bits (79), Expect = 1.6
Identities = 14/17 (82%), Positives = 15/17 (88%)
Frame = +1
Query: 448 LXNLNLEYVDLYLIHWP 498
L +L LEYVDLYLIHWP
Sbjct: 100 LKDLQLEYVDLYLIHWP 116
>UniRef50_A3LWP0 Cluster: Aldo/keto reductase; n=7;
Saccharomycetales|Rep: Aldo/keto reductase - Pichia
stipitis (Yeast)
Length = 323
Score = 48.8 bits (111), Expect = 2e-04
Identities = 28/94 (29%), Positives = 46/94 (48%), Gaps = 1/94 (1%)
Frame = +3
Query: 357 GLKRESIFITTKLWNSYHEREQVIPALRKSLXKSQLGIRRPVFDS-LAHSYV*ERYLARH 533
G+ RE +FITTK + + + + ++ + D L HS E ++R
Sbjct: 87 GIAREDLFITTKYTPGFRTFPAISSGPTEFIDRALKELETDYVDLFLIHSPFFEEKVSRG 146
Query: 534 VDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQR 635
W +IDAKK G + IG+SNF++E ++R
Sbjct: 147 QTLESAWAEVIDAKKAGKVRHIGVSNFSKEHLER 180
Score = 35.9 bits (79), Expect = 1.6
Identities = 19/56 (33%), Positives = 30/56 (53%), Gaps = 1/56 (1%)
Frame = +2
Query: 194 WLGH-RPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQVGRALXQEILRR 358
WL RP+ + +T + +++ ALE GY HIDTA Y +V A+ + + R
Sbjct: 35 WLKKGRPEEEQNTLTTELVDSILLALENGYNHIDTAEVYTTHPEVAAAVKKSGIAR 90
>UniRef50_A3LTU8 Cluster: D-arabinose dehydrogenase; n=5;
Saccharomycetales|Rep: D-arabinose dehydrogenase -
Pichia stipitis (Yeast)
Length = 326
Score = 48.8 bits (111), Expect = 2e-04
Identities = 27/64 (42%), Positives = 39/64 (60%)
Frame = +2
Query: 152 LSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQVGR 331
LS+G IP + LGT P ++ ++ VI A++AGY HIDTA+ YG E+ +G+
Sbjct: 12 LSNGKTIPALGLGTVPPEDP--------HELKEQVITAVKAGYRHIDTAWYYGTEEYIGQ 63
Query: 332 ALXQ 343
AL Q
Sbjct: 64 ALKQ 67
>UniRef50_Q10494 Cluster: Probable oxidoreductase C26F1.07; n=2;
Schizosaccharomyces pombe|Rep: Probable oxidoreductase
C26F1.07 - Schizosaccharomyces pombe (Fission yeast)
Length = 321
Score = 48.8 bits (111), Expect = 2e-04
Identities = 35/118 (29%), Positives = 58/118 (49%), Gaps = 10/118 (8%)
Frame = +3
Query: 357 GLKRESIFITTKLWNSYHEREQVIPALRKSLXKSQLG------IRRPV-FDSLAHSYV*E 515
G+ R+ I++T+KLW + H E V AL K+L +L I PV F + + +
Sbjct: 74 GVPRKDIWVTSKLWCNAHAPEAVPKALEKTLKDLKLDYLDEYLIHWPVSFKTGEDKFPKD 133
Query: 516 R---YLARHVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGLEKPSALQIE 680
+ + +TW+ M + G + IG+SNFN ++RI+ KP+ Q+E
Sbjct: 134 KDGNLIYEKNPIEETWKAMEKLLETGKVRHIGLSNFNDTNLERILKVAKVKPAVHQME 191
Score = 45.2 bits (102), Expect = 0.003
Identities = 26/64 (40%), Positives = 33/64 (51%)
Frame = +2
Query: 152 LSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQVGR 331
L+ G IP + LGTW N T+ AV AL+ GY HID A YG ED+VG
Sbjct: 18 LADGSKIPGLGLGTWRSE---------PNQTKNAVKTALQYGYRHIDAAAIYGNEDEVGD 68
Query: 332 ALXQ 343
+ +
Sbjct: 69 GIKE 72
>UniRef50_A2RMU6 Cluster: Oxidoreductase, aldo/keto reductase
family; n=3; Lactococcus lactis|Rep: Oxidoreductase,
aldo/keto reductase family - Lactococcus lactis subsp.
cremoris (strain MG1363)
Length = 281
Score = 48.4 bits (110), Expect = 3e-04
Identities = 37/111 (33%), Positives = 55/111 (49%), Gaps = 1/111 (0%)
Frame = +3
Query: 351 SEGLKRESIFITTKLWNS-YHEREQVIPALRKSLXKSQLGIRRPVFDSLAHSYV*ERYLA 527
S G+ I+IT+KLW S Y + Q I + + L Q+ + L H V
Sbjct: 62 SSGIPISEIWITSKLWPSDYDDASQAIERMLELLNLKQIDLL------LLHQQV------ 109
Query: 528 RHVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGLEKPSALQIE 680
++ W + +A K G KSIGISNF+ E++ + + KPSALQ+E
Sbjct: 110 --GNYRKAWIALENAVKSGKVKSIGISNFDGERLVDLFNFADIKPSALQVE 158
Score = 41.1 bits (92), Expect = 0.043
Identities = 27/62 (43%), Positives = 33/62 (53%)
Frame = +2
Query: 152 LSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQVGR 331
L+ G IP LG + P+G+ TE AV AL GY HIDTA+ Y E VGR
Sbjct: 7 LNDGNIIPQFGLGVY--QIPEGEA------TENAVKEALRLGYRHIDTAHAYQNERSVGR 58
Query: 332 AL 337
A+
Sbjct: 59 AI 60
>UniRef50_A0JX62 Cluster: 2,5-didehydrogluconate reductase; n=9;
Bacteria|Rep: 2,5-didehydrogluconate reductase -
Arthrobacter sp. (strain FB24)
Length = 291
Score = 48.4 bits (110), Expect = 3e-04
Identities = 31/107 (28%), Positives = 53/107 (49%)
Frame = +3
Query: 360 LKRESIFITTKLWNSYHEREQVIPALRKSLXKSQLGIRRPVFDSLAHSYV*ERYLARHVD 539
L RE +F+TTK+WN H + + A S+ S LG+ Y+ AR
Sbjct: 83 LSREDLFVTTKVWNDDHGYDATMRAFDTSM--SNLGME------YVDLYLIHWPCARRGL 134
Query: 540 FLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGLEKPSALQIE 680
F +++R M + G ++IG+SNF ++ ++++ P+ QIE
Sbjct: 135 FTESYRAMETLYREGRIRAIGVSNFQPAHLEHLLETAEVVPAVNQIE 181
Score = 37.5 bits (83), Expect = 0.53
Identities = 18/33 (54%), Positives = 20/33 (60%)
Frame = +2
Query: 239 DTEQAVIYALEAGYTHIDTAYKYGIEDQVGRAL 337
D V ALEAGY H DTA YG E VG+A+
Sbjct: 29 DAAGLVTMALEAGYRHFDTAAMYGNETGVGKAI 61
Score = 37.5 bits (83), Expect = 0.53
Identities = 14/19 (73%), Positives = 16/19 (84%)
Frame = +1
Query: 448 LXNLNLEYVDLYLIHWPIA 504
+ NL +EYVDLYLIHWP A
Sbjct: 112 MSNLGMEYVDLYLIHWPCA 130
>UniRef50_Q4P1G1 Cluster: Putative uncharacterized protein; n=1;
Ustilago maydis|Rep: Putative uncharacterized protein -
Ustilago maydis (Smut fungus)
Length = 320
Score = 48.4 bits (110), Expect = 3e-04
Identities = 21/46 (45%), Positives = 31/46 (67%)
Frame = +3
Query: 543 LDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGLEKPSALQIE 680
+D W+ + K+ GLTKSIG+SN+ IQ+++D+GL P QIE
Sbjct: 124 VDAWKELEKIKQAGLTKSIGVSNWLASDIQQLLDAGLSVPDINQIE 169
>UniRef50_Q89JN4 Cluster: Oxidoreductase; n=8; Rhizobiales|Rep:
Oxidoreductase - Bradyrhizobium japonicum
Length = 272
Score = 48.0 bits (109), Expect = 4e-04
Identities = 29/110 (26%), Positives = 57/110 (51%)
Frame = +3
Query: 351 SEGLKRESIFITTKLWNSYHEREQVIPALRKSLXKSQLGIRRPVFDSLAHSYV*ERYLAR 530
+ G++R+ +F+TTK+W ++ + ++++SL + +R P D L +
Sbjct: 59 ASGVRRDDVFLTTKVWTNHFAPNDLERSVKESLAR----LRLPSVDLLLLHWP-----NS 109
Query: 531 HVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGLEKPSALQIE 680
HV +T + A+++GLT+ IG+SNF I++ + E Q+E
Sbjct: 110 HVPLAETLGALSHARQMGLTRHIGVSNFTVALIEQAVALSPEPLVCNQVE 159
Score = 42.3 bits (95), Expect = 0.018
Identities = 27/69 (39%), Positives = 35/69 (50%), Gaps = 1/69 (1%)
Frame = +2
Query: 155 SSGGNIPVVALGTW-LGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQVGR 331
++G IP + LGTW L RP +VV+ AL GY HIDTA Y E +VG
Sbjct: 6 ANGARIPAIGLGTWELSGRPCARVVE----------QALRLGYRHIDTAQVYDNEREVGD 55
Query: 332 ALXQEILRR 358
+ +RR
Sbjct: 56 GVRASGVRR 64
>UniRef50_Q6NII7 Cluster: Putative oxidoreductase; n=2;
Corynebacterium|Rep: Putative oxidoreductase -
Corynebacterium diphtheriae
Length = 290
Score = 48.0 bits (109), Expect = 4e-04
Identities = 28/72 (38%), Positives = 41/72 (56%)
Frame = +2
Query: 134 IVPTLQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGI 313
I+PT+ L+ G +P + GT+ K+ + D +AV A+E GY HIDTA Y
Sbjct: 10 IIPTITLNDGTEMPAIGFGTY-------KLRE--QDAYRAVRSAIEVGYRHIDTASLYKN 60
Query: 314 EDQVGRALXQEI 349
E++VGRA+ I
Sbjct: 61 EEEVGRAVADAI 72
Score = 33.5 bits (73), Expect = 8.6
Identities = 25/105 (23%), Positives = 53/105 (50%)
Frame = +3
Query: 366 RESIFITTKLWNSYHEREQVIPALRKSLXKSQLGIRRPVFDSLAHSYV*ERYLARHVDFL 545
R+ +FITTK+WN H + + ++SL + LG+ + + H ++ L ++
Sbjct: 79 RDELFITTKVWNDMHGDQLTQRSFQESLHR--LGLDY-IDCCMVHWPWPQKGL-----YV 130
Query: 546 DTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGLEKPSALQIE 680
+++ + + LG +S+ ++NF E ++ I+ P Q+E
Sbjct: 131 ESFAALAKIQGLGQLQSVAVANFYPEVLREIVAETGIAPVLNQVE 175
>UniRef50_Q03PG5 Cluster: Aldo/keto reductase of diketogulonate
reductase family; n=1; Lactobacillus brevis ATCC
367|Rep: Aldo/keto reductase of diketogulonate reductase
family - Lactobacillus brevis (strain ATCC 367 / JCM
1170)
Length = 268
Score = 48.0 bits (109), Expect = 4e-04
Identities = 32/113 (28%), Positives = 58/113 (51%), Gaps = 3/113 (2%)
Frame = +3
Query: 351 SEGLKRESIFITTKLWNSYHEREQVIPALRKSLXKSQLGIRRPVFDSLAHSYV*ERYLAR 530
+ G+ R +FIT+K+WN+ ++ + A ++L QL D L + +
Sbjct: 60 ASGIDRSDLFITSKVWNADQGYDKTLAAFDQTLSDLQL-------DYLDLYLI---HWPN 109
Query: 531 HVDF---LDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGLEKPSALQIE 680
DF LDTWR + + ++IG+SNF+++Q++++ + KP QIE
Sbjct: 110 EDDFELTLDTWRVLETLYQQKKVRAIGVSNFSEDQLKQVFEMATVKPMINQIE 162
Score = 44.0 bits (99), Expect = 0.006
Identities = 26/65 (40%), Positives = 36/65 (55%)
Frame = +2
Query: 143 TLQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQ 322
T QLS+G IP++ GT+L + D A+ AL+AGY H+D A+ YG E
Sbjct: 3 TTQLSNGVTIPMLGFGTYLID---------SKDVPAAIKTALDAGYRHLDCAHIYGNEPA 53
Query: 323 VGRAL 337
VG A+
Sbjct: 54 VGEAI 58
Score = 36.3 bits (80), Expect = 1.2
Identities = 16/30 (53%), Positives = 21/30 (70%)
Frame = +1
Query: 448 LXNLNLEYVDLYLIHWPIAMFENDTLLDTW 537
L +L L+Y+DLYLIHWP + + LDTW
Sbjct: 92 LSDLQLDYLDLYLIHWP-NEDDFELTLDTW 120
>UniRef50_Q7ZA52 Cluster: Aldose reductase; n=6; Pezizomycotina|Rep:
Aldose reductase - Magnaporthe grisea (Rice blast
fungus) (Pyricularia grisea)
Length = 312
Score = 48.0 bits (109), Expect = 4e-04
Identities = 29/77 (37%), Positives = 44/77 (57%)
Frame = +2
Query: 152 LSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQVGR 331
L++G IP LGTW G KG + ++AV+ A+++GY ID AY YG E++VG+
Sbjct: 8 LNTGAKIPAFGLGTWQGD--KGVI-------KEAVLTAIKSGYRLIDGAYVYGNEEEVGQ 58
Query: 332 ALXQEILRRT*KRIYLY 382
+ + I KR L+
Sbjct: 59 GIREAISSGIVKREDLF 75
Score = 39.1 bits (87), Expect = 0.17
Identities = 27/118 (22%), Positives = 54/118 (45%), Gaps = 11/118 (9%)
Frame = +3
Query: 360 LKRESIFITTKLWNSYHER-EQVIPALRKSLXKSQLGIRRPVFDSLAHSYV*ERYLARHV 536
+KRE +F+ +K W +Y R E + K L + + + L + + +H
Sbjct: 69 VKREDLFVVSKCWATYTTRCELGLDQSLKLLGLDYVDLYLVHWPILMNPEGNDEKFPKHA 128
Query: 537 D----------FLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGLEKPSALQIE 680
D +DTW+ M G TK++G+SN+++ +++++ P+ Q+E
Sbjct: 129 DGSRDIIHTHNHVDTWKLMEKLPATGKTKAVGVSNYSKAWLEQLLPHATTVPAVNQVE 186
Score = 35.9 bits (79), Expect = 1.6
Identities = 13/17 (76%), Positives = 15/17 (88%)
Frame = +1
Query: 457 LNLEYVDLYLIHWPIAM 507
L L+YVDLYL+HWPI M
Sbjct: 99 LGLDYVDLYLVHWPILM 115
>UniRef50_Q6RZX1 Cluster: Gld1; n=22; Pezizomycotina|Rep: Gld1 -
Trichoderma atroviride (Hypocrea atroviridis)
Length = 327
Score = 48.0 bits (109), Expect = 4e-04
Identities = 28/72 (38%), Positives = 38/72 (52%)
Frame = +2
Query: 143 TLQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQ 322
T L++G IP V GT+ KG +T AV AL+ GY H+D A+ Y ED+
Sbjct: 14 TYTLNTGAKIPAVGFGTFANEGAKG-------ETYAAVTKALDVGYRHLDCAWFYLNEDE 66
Query: 323 VGRALXQEILRR 358
VG A+ + RR
Sbjct: 67 VGDAIRDFLARR 78
Score = 39.5 bits (88), Expect = 0.13
Identities = 32/121 (26%), Positives = 54/121 (44%), Gaps = 16/121 (13%)
Frame = +3
Query: 366 RESIFITTKLWNSYHEREQVIPALRKSLXK----------------SQLGIRRPVFDSLA 497
R+ +FI TK+WN HE E V + + S ++ R V
Sbjct: 83 RKDLFICTKVWNHLHEPEDVKWSAKNSCENLKVDYIDLFLVHWPIAAEKNADRTVKIGPD 142
Query: 498 HSYV*ERYLARHVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGLEKPSALQI 677
YV + L + + TWR M + G+ K+IG+SN+ ++++++ KP+ QI
Sbjct: 143 GKYVINKALTENPE--PTWRAMEELVDSGIVKAIGVSNWTIPGLKQLLEFARIKPAVNQI 200
Query: 678 E 680
E
Sbjct: 201 E 201
Score = 36.3 bits (80), Expect = 1.2
Identities = 12/21 (57%), Positives = 18/21 (85%)
Frame = +1
Query: 454 NLNLEYVDLYLIHWPIAMFEN 516
NL ++Y+DL+L+HWPIA +N
Sbjct: 112 NLKVDYIDLFLVHWPIAAEKN 132
>UniRef50_Q5B034 Cluster: Putative uncharacterized protein; n=1;
Emericella nidulans|Rep: Putative uncharacterized
protein - Emericella nidulans (Aspergillus nidulans)
Length = 186
Score = 48.0 bits (109), Expect = 4e-04
Identities = 29/96 (30%), Positives = 50/96 (52%), Gaps = 1/96 (1%)
Frame = +3
Query: 357 GLKRESIFITTKLWNSYHER-EQVIPALRKSLXKSQLGIRRPVFDSLAHSYV*ERYLARH 533
G+ RE IFIT+KLWN++ ++ + +L L + D L + R + R
Sbjct: 50 GVPREEIFITSKLWNTHQPNIKEGLQKTLDALGVDCLDLYNETSDLLPVNPDGTRAVDRS 109
Query: 534 VDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRII 641
D +TWR M D K G K+IG++N++ ++ ++
Sbjct: 110 WDQSETWRQMEDFYKSGKAKAIGVANWSIPYLEELL 145
>UniRef50_Q5T2L2 Cluster: Aldo-keto reductase family 1 member C-like
protein 1; n=14; Eutheria|Rep: Aldo-keto reductase
family 1 member C-like protein 1 - Homo sapiens (Human)
Length = 302
Score = 48.0 bits (109), Expect = 4e-04
Identities = 26/77 (33%), Positives = 45/77 (58%), Gaps = 1/77 (1%)
Frame = +2
Query: 143 TLQLSSGGNIPVVALGTWL-GHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIED 319
+++L+ G +PV+ GT+ H PK + + T A++ G+ HID+AY Y E+
Sbjct: 10 SVRLNDGPFMPVLGFGTYAPDHTPKSQAAEATK-------VAIDVGFRHIDSAYLYQNEE 62
Query: 320 QVGRALXQEILRRT*KR 370
+VG+A+ ++I T KR
Sbjct: 63 EVGQAIWEKIADGTVKR 79
Score = 38.7 bits (86), Expect = 0.23
Identities = 19/39 (48%), Positives = 26/39 (66%), Gaps = 1/39 (2%)
Frame = +3
Query: 342 KKFSEG-LKRESIFITTKLWNSYHEREQVIPALRKSLXK 455
+K ++G +KRE IF T KLW ++ E V PAL +SL K
Sbjct: 70 EKIADGTVKREEIFYTIKLWATFFRAELVHPALERSLKK 108
>UniRef50_A5KSS3 Cluster: Aldehyde reductase; n=1; candidate
division TM7 genomosp. GTL1|Rep: Aldehyde reductase -
candidate division TM7 genomosp. GTL1
Length = 299
Score = 47.6 bits (108), Expect = 5e-04
Identities = 34/117 (29%), Positives = 55/117 (47%), Gaps = 10/117 (8%)
Frame = +3
Query: 360 LKRESIFITTKLWNSYHEREQVIPALRKSLXKSQL----------GIRRPVFDSLAHSYV 509
+KRE +F+T+KLWN+ H + V A RK+L L G+ D+L
Sbjct: 67 VKREDLFVTSKLWNTDHAQVDVGVACRKTLNDLGLDYLDLYLIHWGVAFEHGDNLEPLDD 126
Query: 510 *ERYLARHVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGLEKPSALQIE 680
+ +TW+ M + + GL KS+G++NF + ++ KP+ QIE
Sbjct: 127 DGVAKFSFISMKETWQAMEELVEQGLVKSMGVANFTAPMLLDLLSYAKIKPAVHQIE 183
Score = 37.5 bits (83), Expect = 0.53
Identities = 27/79 (34%), Positives = 38/79 (48%)
Frame = +2
Query: 146 LQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQV 325
L L + +P++ GTW P G T V A++AGY HID A YG E +V
Sbjct: 4 LTLRNKQTLPLLGYGTW--ELPTGT-------TADLVETAIKAGYRHIDCAMIYGNEKEV 54
Query: 326 GRALXQEILRRT*KRIYLY 382
G + + I + KR L+
Sbjct: 55 GEGIRRTIDQGVVKREDLF 73
Score = 35.5 bits (78), Expect = 2.1
Identities = 14/26 (53%), Positives = 18/26 (69%)
Frame = +1
Query: 448 LXNLNLEYVDLYLIHWPIAMFENDTL 525
L +L L+Y+DLYLIHW +A D L
Sbjct: 96 LNDLGLDYLDLYLIHWGVAFEHGDNL 121
>UniRef50_Q572D2 Cluster: Aldo-keto reductase, putative; n=1;
Phytophthora infestans|Rep: Aldo-keto reductase,
putative - Phytophthora infestans (Potato late blight
fungus)
Length = 255
Score = 47.6 bits (108), Expect = 5e-04
Identities = 27/67 (40%), Positives = 38/67 (56%)
Frame = +2
Query: 137 VPTLQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIE 316
VPT L SG IP++ LG + + +T A++ +L+ GY HIDTA YG E
Sbjct: 5 VPTKILPSGARIPMIGLGVYQS--------EPGPETYNAILTSLKLGYRHIDTAEIYGNE 56
Query: 317 DQVGRAL 337
+ VGRA+
Sbjct: 57 EDVGRAV 63
Score = 43.2 bits (97), Expect = 0.011
Identities = 32/108 (29%), Positives = 55/108 (50%)
Frame = +3
Query: 357 GLKRESIFITTKLWNSYHEREQVIPALRKSLXKSQLGIRRPVFDSLAHSYV*ERYLARHV 536
G+ RE IF+TTKL+ + + + A + S +LGI ++ L H+ + A
Sbjct: 67 GIPREEIFVTTKLFTTNWGYSKALAAGKAS--NDRLGIVY-IYLYLLHAPGPPKERA--- 120
Query: 537 DFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGLEKPSALQIE 680
DTWR + D ++ + IG+SNFN+ + + + KP+ Q+E
Sbjct: 121 ---DTWRAVEDLREQETLRDIGVSNFNETLLATLRKTAHIKPAVNQVE 165
>UniRef50_Q22352 Cluster: Putative uncharacterized protein T08H10.1;
n=2; Caenorhabditis|Rep: Putative uncharacterized
protein T08H10.1 - Caenorhabditis elegans
Length = 333
Score = 47.6 bits (108), Expect = 5e-04
Identities = 37/118 (31%), Positives = 53/118 (44%), Gaps = 11/118 (9%)
Frame = +3
Query: 360 LKRESIFITTKLWNSYHEREQVIPALRKSLXKSQLG------IRRPV-----FDSLAHSY 506
LKRE IF+T+KL + H E V + L QL I P S A
Sbjct: 70 LKREDIFVTSKLPFTAHAPEDVPKCVESQLKALQLEYIDLYLIHCPFPFKHQEGSFAPLM 129
Query: 507 V*ERYLARHVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGLEKPSALQIE 680
+ +DTWR + K G K++G+SNF+ Q+Q + D+ KP+ Q+E
Sbjct: 130 ENGELAVTEIAHIDTWRALEKLYKEGKLKALGVSNFSCNQLQALYDAAEVKPANQQVE 187
Score = 41.9 bits (94), Expect = 0.024
Identities = 33/110 (30%), Positives = 49/110 (44%), Gaps = 2/110 (1%)
Frame = +2
Query: 131 LIVPTLQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIY--ALEAGYTHIDTAYK 304
+ V ++ L++G +P+ LGTW QV ++ E V AL+AGY IDTA+
Sbjct: 1 MTVDSIPLNTGAQLPLFGLGTW----------QVKDEAELTVALRAALDAGYRLIDTAHL 50
Query: 305 YGIEDQVGRALXQEILRRT*KRIYLYNYQALEFLPRERASDPSAEEVPXK 454
Y E +G+ L + I KR ++ L F P E K
Sbjct: 51 YQNEHIIGKVLHEYISSGKLKREDIFVTSKLPFTAHAPEDVPKCVESQLK 100
>UniRef50_Q6CFG7 Cluster: Yarrowia lipolytica chromosome B of strain
CLIB122 of Yarrowia lipolytica; n=9; Ascomycota|Rep:
Yarrowia lipolytica chromosome B of strain CLIB122 of
Yarrowia lipolytica - Yarrowia lipolytica (Candida
lipolytica)
Length = 337
Score = 47.6 bits (108), Expect = 5e-04
Identities = 38/124 (30%), Positives = 61/124 (49%), Gaps = 11/124 (8%)
Frame = +3
Query: 342 KKFSEGLKRESIFITTKLWNSYHER-EQVIPALRKSL---XKSQLGIRRPV-FDSLAHS- 503
+ +G+KRE IF+TTK+W +YH+R E+ + + L L I PV + +
Sbjct: 91 RAMEKGVKREDIFVTTKIWVTYHDRVEENLDMSLERLGLDYVDMLLIHWPVPLNPNGNDP 150
Query: 504 -YV*ERYLARHVDFL----DTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGLEKPSA 668
Y +R +D TW+ M K G TKSIG+SNF+ ++ ++ P+
Sbjct: 151 VYPLRPDGSRDIDESGSQPKTWKQMEAVLKTGKTKSIGVSNFSIPYLEELLKEAEVVPAV 210
Query: 669 LQIE 680
Q+E
Sbjct: 211 NQVE 214
Score = 43.2 bits (97), Expect = 0.011
Identities = 25/59 (42%), Positives = 31/59 (52%)
Frame = +2
Query: 152 LSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQVG 328
L++G IP + LGTW K +V E A+ E GY HIDTA+ Y ED VG
Sbjct: 36 LNNGKTIPAIGLGTW-----KSTTEEVAGAVECALT---EGGYRHIDTAFNYRNEDAVG 86
>UniRef50_P23901 Cluster: Aldose reductase; n=9; Poaceae|Rep: Aldose
reductase - Hordeum vulgare (Barley)
Length = 320
Score = 47.6 bits (108), Expect = 5e-04
Identities = 27/63 (42%), Positives = 37/63 (58%), Gaps = 1/63 (1%)
Frame = +2
Query: 152 LSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYAL-EAGYTHIDTAYKYGIEDQVG 328
L SG +P V LGTW + +DT +V A+ EAGY H+DTA +YG+E +VG
Sbjct: 18 LKSGHAMPAVGLGTW----------RAGSDTAHSVRTAITEAGYRHVDTAAEYGVEKEVG 67
Query: 329 RAL 337
+ L
Sbjct: 68 KGL 70
Score = 45.2 bits (102), Expect = 0.003
Identities = 32/114 (28%), Positives = 51/114 (44%), Gaps = 6/114 (5%)
Frame = +3
Query: 357 GLKRESIFITTKLWNSYHEREQVIPALRKSLXKSQLG------IRRPVFDSLAHSYV*ER 518
G+ R+ +F+T+K+W + E+V PAL +L QL I P E
Sbjct: 77 GIDRKDLFVTSKIWCTNLAPERVRPALENTLKDLQLDYIDLYHIHWPFRLKDGAHMPPEA 136
Query: 519 YLARHVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGLEKPSALQIE 680
D W+ M + K GL K IG+ N+ ++ R++ S P+ Q+E
Sbjct: 137 GEVLEFDMEGVWKEMENLVKDGLVKDIGVCNYTVTKLNRLLRSAKIPPAVCQME 190
>UniRef50_UPI0000519CC2 Cluster: PREDICTED: similar to CG2767-PA;
n=1; Apis mellifera|Rep: PREDICTED: similar to CG2767-PA
- Apis mellifera
Length = 321
Score = 47.2 bits (107), Expect = 7e-04
Identities = 42/122 (34%), Positives = 60/122 (49%), Gaps = 12/122 (9%)
Frame = +3
Query: 351 SEGLKRESIFITTKLWNSYHEREQVIPALRKSLXKSQLG------IRRPV-FDSLA---H 500
S+ LKR IFI TKL + E V ++ SL +L I P+ F+ + H
Sbjct: 66 SKKLKRSDIFIVTKLPAVGNRAEDVEKWIKTSLQNLRLEYLDLYLIHVPIGFEKVGDILH 125
Query: 501 SYV*ERY--LARHVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGLEKPSALQ 674
+ + L + ++ W M K G TK+IG+SNFN QI+RI+ + K S LQ
Sbjct: 126 PFDENGHIRLDNSTNHVEIWAEMEKQVKCGRTKAIGLSNFNISQIKRILKNTKMKISMLQ 185
Query: 675 IE 680
IE
Sbjct: 186 IE 187
Score = 41.5 bits (93), Expect = 0.032
Identities = 24/65 (36%), Positives = 32/65 (49%)
Frame = +2
Query: 143 TLQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQ 322
T+ L +G +P++ GTW + E A+ ALEAGY HIDTA Y E
Sbjct: 5 TILLPNGELMPIIGFGTWQAQE---------KELEDALNIALEAGYRHIDTATSYENEKV 55
Query: 323 VGRAL 337
+G L
Sbjct: 56 IGDVL 60
>UniRef50_Q9ZBW7 Cluster: Putative oxidoreductase; n=2;
Actinomycetales|Rep: Putative oxidoreductase -
Streptomyces coelicolor
Length = 277
Score = 47.2 bits (107), Expect = 7e-04
Identities = 34/118 (28%), Positives = 54/118 (45%)
Frame = +3
Query: 327 EGPXTKKFSEGLKRESIFITTKLWNSYHEREQVIPALRKSLXKSQLGIRRPVFDSLAHSY 506
EG + GL RE +F+TTKLWNS + + A S+ K LG+ Y
Sbjct: 56 EGTGRAIAASGLAREDLFVTTKLWNSDQGYDSTLRAFDTSMAK--LGL------EYLDLY 107
Query: 507 V*ERYLARHVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGLEKPSALQIE 680
+ + ++DT++ G ++IG+SNF E ++R+ P+ QIE
Sbjct: 108 LIHWPMPAKERYVDTYKAFEKLLADGRVRAIGVSNFLPEHLERLTAETSVIPAVNQIE 165
Score = 45.2 bits (102), Expect = 0.003
Identities = 31/75 (41%), Positives = 39/75 (52%), Gaps = 1/75 (1%)
Frame = +2
Query: 137 VPTLQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQ-AVIYALEAGYTHIDTAYKYGI 313
VP + L++G +P + G W QV +D Q AV ALEAGY IDTA YG
Sbjct: 5 VPPIILNNGVEMPQLGFGVW----------QVPDDDAQTAVALALEAGYRSIDTAAIYGN 54
Query: 314 EDQVGRALXQEILRR 358
E+ GRA+ L R
Sbjct: 55 EEGTGRAIAASGLAR 69
>UniRef50_Q03XK0 Cluster: Aldo/keto reductase of diketogulonate
reductase family; n=3; Lactobacillales|Rep: Aldo/keto
reductase of diketogulonate reductase family -
Leuconostoc mesenteroides subsp. mesenteroides (strain
ATCC 8293 /NCDO 523)
Length = 292
Score = 47.2 bits (107), Expect = 7e-04
Identities = 33/107 (30%), Positives = 51/107 (47%)
Frame = +3
Query: 360 LKRESIFITTKLWNSYHEREQVIPALRKSLXKSQLGIRRPVFDSLAHSYV*ERYLARHVD 539
+KRE +F+T+K+W +Q A++ SL + L D L + + Y D
Sbjct: 68 VKREELFVTSKMWVQDVSAQQATAAIQSSLQRLNL-------DYLDLYLIHQPYN----D 116
Query: 540 FLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGLEKPSALQIE 680
WR M A + G K+IG+SNF+ Q+ + + KP QIE
Sbjct: 117 VFGAWRAMESAYRSGQLKAIGVSNFDIAQLTNLAEFSDIKPMLNQIE 163
Score = 39.9 bits (89), Expect = 0.099
Identities = 27/77 (35%), Positives = 41/77 (53%)
Frame = +2
Query: 152 LSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQVGR 331
L+SG +P++ G + VQ +QAV+ A++ GY IDTA YG E +VG
Sbjct: 6 LASGIEMPLLGFGVFQ--------VQEKGAAKQAVLDAIKTGYRLIDTAASYGNEREVGE 57
Query: 332 ALXQEILRRT*KRIYLY 382
A+ + I + KR L+
Sbjct: 58 AILEAINQGIVKREELF 74
>UniRef50_A0AWM8 Cluster: Aldo/keto reductase; n=4;
Actinomycetales|Rep: Aldo/keto reductase - Arthrobacter
sp. (strain FB24)
Length = 287
Score = 47.2 bits (107), Expect = 7e-04
Identities = 25/67 (37%), Positives = 39/67 (58%)
Frame = +2
Query: 137 VPTLQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIE 316
+P L+L G IP + LGTW + ++ E AV +AL++GY +DTA++Y E
Sbjct: 13 IPRLKLPHGHTIPRLGLGTW---------PMLEDECETAVRFALQSGYRLVDTAFQYRNE 63
Query: 317 DQVGRAL 337
+ VGR +
Sbjct: 64 EAVGRGI 70
Score = 40.7 bits (91), Expect = 0.056
Identities = 33/108 (30%), Positives = 53/108 (49%)
Frame = +3
Query: 357 GLKRESIFITTKLWNSYHEREQVIPALRKSLXKSQLGIRRPVFDSLAHSYV*ERYLARHV 536
G+ R +FI++K H + V A +SL K L +F + H V L ++V
Sbjct: 74 GVPRSELFISSKFNKESHSIDGVQRAYDESLRKLGLD-HLDMF--MCHWPV--PALGKYV 128
Query: 537 DFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGLEKPSALQIE 680
D W+G++ + G K+IG+SNF ++ IID+ P QI+
Sbjct: 129 D---AWKGLVKLLEEGRVKAIGVSNFKPAHLKDIIDATGVVPDVNQIQ 173
>UniRef50_Q7VG53 Cluster: Aldo-keto reductase; n=28; Bacteria|Rep:
Aldo-keto reductase - Helicobacter hepaticus
Length = 292
Score = 46.8 bits (106), Expect = 9e-04
Identities = 29/106 (27%), Positives = 54/106 (50%)
Frame = +3
Query: 360 LKRESIFITTKLWNSYHEREQVIPALRKSLXKSQLGIRRPVFDSLAHSYV*ERYLARHVD 539
+KRE +FIT+K+ Y + + ++ SL +L + + R +
Sbjct: 74 IKREELFITSKIRAEYKDYKSASASIDTSLKTMKLDFIDLMLIHSPQPWNSFRKGDYFKE 133
Query: 540 FLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGLEKPSALQI 677
++ + + DA+K G +SIG+SNF Q+ ++ I+ + KP+A QI
Sbjct: 134 NVEVYNALEDAQKAGKVRSIGVSNFLQKDLENILKNCKTKPAANQI 179
Score = 44.8 bits (101), Expect = 0.003
Identities = 29/69 (42%), Positives = 37/69 (53%)
Frame = +2
Query: 152 LSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQVGR 331
L++G IP + LGTW R VV E AV A + GY HIDTA YG E VG
Sbjct: 17 LNNGNKIPKLGLGTW---RIDDNVV------EAAVREAFKVGYRHIDTAQAYGNERGVGE 67
Query: 332 ALXQEILRR 358
A+ + ++R
Sbjct: 68 AVRKSKIKR 76
>UniRef50_Q14LU6 Cluster: Putative aldo/keto reductase
oxidoreductase protein; n=1; Spiroplasma citri|Rep:
Putative aldo/keto reductase oxidoreductase protein -
Spiroplasma citri
Length = 138
Score = 46.8 bits (106), Expect = 9e-04
Identities = 30/78 (38%), Positives = 46/78 (58%)
Frame = +2
Query: 146 LQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQV 325
L+L +G IP++ LGT+ K+ ++ QA+I AL+ GY HIDTA YG E+ +
Sbjct: 8 LKLFNGVEIPLIGLGTY-------KMTD-EHEVYQAIITALQNGYRHIDTAQIYGNEELI 59
Query: 326 GRALXQEILRRT*KRIYL 379
G+A+ + R K I+L
Sbjct: 60 GKAIKDSGVPR--KEIFL 75
>UniRef50_Q9VHX4 Cluster: CG2767-PA; n=4; Endopterygota|Rep:
CG2767-PA - Drosophila melanogaster (Fruit fly)
Length = 329
Score = 46.8 bits (106), Expect = 9e-04
Identities = 26/64 (40%), Positives = 34/64 (53%)
Frame = +2
Query: 146 LQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQV 325
L ++G +PV+ +GTW + E A+ ALEAGY HIDTA YG E +
Sbjct: 7 LTFNNGEKMPVIGIGTWQAS---------DEEIETAIDAALEAGYRHIDTAPVYGNEKAI 57
Query: 326 GRAL 337
GR L
Sbjct: 58 GRVL 61
Score = 46.0 bits (104), Expect = 0.002
Identities = 36/119 (30%), Positives = 60/119 (50%), Gaps = 12/119 (10%)
Frame = +3
Query: 360 LKRESIFITTKLWNSYHEREQVIPALRKSLXKSQLG------IRRPVFDSLAH--SYV*E 515
+KRE +FI TK+ + +V P ++KSL QL + P ++ S+ +
Sbjct: 70 VKREELFIVTKVPPVSNRPHEVEPTIKKSLEDLQLDYVDLYLVHTPFTININEDGSFKLD 129
Query: 516 RYLARHVDFLDT----WRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGLEKPSALQIE 680
+ VD W M + GLTKSIG+SNF+++Q+ R++ + +P+ QIE
Sbjct: 130 KEGLMEVDVTTNHAAIWVAMEALVEKGLTKSIGVSNFSKDQVARLLKNCKIRPANNQIE 188
>UniRef50_Q3E9M9 Cluster: Uncharacterized protein At5g01670.2; n=7;
Magnoliophyta|Rep: Uncharacterized protein At5g01670.2 -
Arabidopsis thaliana (Mouse-ear cress)
Length = 349
Score = 46.4 bits (105), Expect = 0.001
Identities = 28/75 (37%), Positives = 41/75 (54%), Gaps = 1/75 (1%)
Frame = +2
Query: 116 FTSADLIVPTLQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYAL-EAGYTHID 292
FTS + + +L SG IP V LGTW + + AV+ A+ E GY HID
Sbjct: 6 FTSEGQNMESFRLLSGHKIPAVGLGTW----------RSGSQAAHAVVTAIVEGGYRHID 55
Query: 293 TAYKYGIEDQVGRAL 337
TA++YG + +VG+ +
Sbjct: 56 TAWEYGDQREVGQGI 70
Score = 37.1 bits (82), Expect = 0.70
Identities = 15/22 (68%), Positives = 17/22 (77%)
Frame = +1
Query: 448 LXNLNLEYVDLYLIHWPIAMFE 513
L L LEY+DLYLIHWPI + E
Sbjct: 134 LKELQLEYLDLYLIHWPIRLRE 155
>UniRef50_Q4Q5N9 Cluster: Prostaglandin f synthase, putative; n=7;
cellular organisms|Rep: Prostaglandin f synthase,
putative - Leishmania major
Length = 279
Score = 46.4 bits (105), Expect = 0.001
Identities = 30/108 (27%), Positives = 51/108 (47%)
Frame = +3
Query: 357 GLKRESIFITTKLWNSYHEREQVIPALRKSLXKSQLGIRRPVFDSLAHSYV*ERYLARHV 536
G+ R IF+TTKLWN H E + A +S + LG+ V L H + +
Sbjct: 66 GVPRSDIFVTTKLWNYDHGYESALAAFEQS--RQALGVEY-VDLYLIH------WPGPNR 116
Query: 537 DFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGLEKPSALQIE 680
+++TWR ++ ++IG+SNF + ++ + P Q+E
Sbjct: 117 SYIETWRAFEKLYEMKKVRAIGVSNFEPHHLDDLLANCTVPPMVNQVE 164
Score = 37.5 bits (83), Expect = 0.53
Identities = 21/64 (32%), Positives = 35/64 (54%)
Frame = +2
Query: 152 LSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQVGR 331
LS+G +P + +GTW + +VV + +A+ AGY H+DTA+ Y E VG+
Sbjct: 10 LSNGVQVPQLGIGTWEA-KDGNEVVNIK--------WAVNAGYRHVDTAHYYKNEKGVGQ 60
Query: 332 ALXQ 343
+ +
Sbjct: 61 GISE 64
>UniRef50_Q235V6 Cluster: Oxidoreductase, aldo/keto reductase family
protein; n=2; Tetrahymena thermophila SB210|Rep:
Oxidoreductase, aldo/keto reductase family protein -
Tetrahymena thermophila SB210
Length = 332
Score = 46.4 bits (105), Expect = 0.001
Identities = 31/112 (27%), Positives = 58/112 (51%), Gaps = 1/112 (0%)
Frame = +3
Query: 348 FSEG-LKRESIFITTKLWNSYHEREQVIPALRKSLXKSQLGIRRPVFDSLAHSYV*ERYL 524
F EG R+ +FI +K++ + + ++ +++KSL + QL + ++ E+
Sbjct: 67 FKEGKYSRKDLFIVSKVFPN--KGINMLESVKKSLKELQLDYVDLYYLHFPLGFLSEKEE 124
Query: 525 ARHVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGLEKPSALQIE 680
H+ W + +A +LGL KSIG+SNFN + ++ KP + Q+E
Sbjct: 125 FVHLPVHVAWAQLEEAHRLGLAKSIGVSNFNVMALADLLSYAKVKPVSNQVE 176
Score = 37.9 bits (84), Expect = 0.40
Identities = 24/63 (38%), Positives = 38/63 (60%)
Frame = +2
Query: 149 QLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQVG 328
+L++G +P+V LGT+L + + ++TN + AL+AGY HIDTA Y E +G
Sbjct: 9 KLNNGQIMPLVGLGTYLLNSKE----EMTN----LLRTALDAGYRHIDTAVNYQNEAMIG 60
Query: 329 RAL 337
+L
Sbjct: 61 ESL 63
>UniRef50_A7SGW6 Cluster: Predicted protein; n=1; Nematostella
vectensis|Rep: Predicted protein - Nematostella
vectensis
Length = 264
Score = 46.4 bits (105), Expect = 0.001
Identities = 31/108 (28%), Positives = 53/108 (49%)
Frame = +3
Query: 357 GLKRESIFITTKLWNSYHEREQVIPALRKSLXKSQLGIRRPVFDSLAHSYV*ERYLARHV 536
GLKRE I++TTKL S + ++S+ K +G V L H+ R
Sbjct: 70 GLKREDIYVTTKLKPSEEGHSNALKYAKESIKKLDIGY---VDLFLIHT-------PRPG 119
Query: 537 DFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGLEKPSALQIE 680
+ + + ++ K+ GL +S+G+SNF ++ + +G P+ QIE
Sbjct: 120 NIIAAYDALLTLKEEGLIRSVGVSNFGVHHLEELRKAGCRTPAINQIE 167
>UniRef50_Q4P4P1 Cluster: Putative uncharacterized protein; n=1;
Ustilago maydis|Rep: Putative uncharacterized protein -
Ustilago maydis (Smut fungus)
Length = 322
Score = 46.4 bits (105), Expect = 0.001
Identities = 30/76 (39%), Positives = 43/76 (56%), Gaps = 2/76 (2%)
Frame = +2
Query: 122 SADLIVPTLQLSSGGNIPVVALGTWLGHRPKGKVVQVTND--TEQAVIYALEAGYTHIDT 295
S ++ ++L++G IP VALG V + ND TE A +A +AGY HID+
Sbjct: 11 SGNISTQRIKLNNGQEIPQVALG----------VYKAPNDGSTENACKWAFDAGYRHIDS 60
Query: 296 AYKYGIEDQVGRALXQ 343
A +Y E+ VGRAL +
Sbjct: 61 AARYMNEESVGRALAE 76
Score = 45.6 bits (103), Expect = 0.002
Identities = 38/128 (29%), Positives = 62/128 (48%)
Frame = +3
Query: 297 HTNMESRTKWEGPXTKKFSEGLKRESIFITTKLWNSYHEREQVIPALRKSLXKSQLGIRR 476
+ N ES + TK+ + R IFIT+KLW++ H++ A+ SL K +
Sbjct: 64 YMNEESVGRALAEWTKE--NNVPRSEIFITSKLWDADHDKAAA--AIEDSLKKLNVDYMD 119
Query: 477 PVFDSLAHSYV*ERYLARHVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGLE 656
L HS R L+ W+ + +A G K+IG+SNF+ E++ ++ +
Sbjct: 120 MY---LMHSPGTMGAEKR----LEAWKALEEAVDAGKIKTIGVSNFDVEELDHLLANCRI 172
Query: 657 KPSALQIE 680
KP+ QIE
Sbjct: 173 KPAVNQIE 180
>UniRef50_A2QVE5 Cluster: Similarity: shows similarity to several
dehydrogenases of different specificities; n=4;
Pezizomycotina|Rep: Similarity: shows similarity to
several dehydrogenases of different specificities -
Aspergillus niger
Length = 381
Score = 46.4 bits (105), Expect = 0.001
Identities = 39/124 (31%), Positives = 60/124 (48%), Gaps = 16/124 (12%)
Frame = +3
Query: 357 GLKRESIFITTKLWNSYHEREQVIPALRKSLXKSQLG------IRRPV--------FDSL 494
GLKRE IFIT+KLWNS H+ V AL + L + +L + PV F +
Sbjct: 70 GLKREDIFITSKLWNSQHDPAVVEKALDECLAELELDYLDLYLVHWPVSFTTGSELFPLV 129
Query: 495 AHSYV--*ERYLARHVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGLEKPSA 668
S V + + + +DTW+ M K +++G+SN ++ II++ P+
Sbjct: 130 KDSSVEGGDVVINDDISIVDTWKAMTQLPK-SKARTVGVSNHMIPHLEAIINATGVVPAV 188
Query: 669 LQIE 680
QIE
Sbjct: 189 NQIE 192
Score = 34.3 bits (75), Expect = 4.9
Identities = 11/19 (57%), Positives = 16/19 (84%)
Frame = +1
Query: 448 LXNLNLEYVDLYLIHWPIA 504
L L L+Y+DLYL+HWP++
Sbjct: 100 LAELELDYLDLYLVHWPVS 118
>UniRef50_Q9X0A2 Cluster: Oxidoreductase, aldo/keto reductase
family; n=21; Bacteria|Rep: Oxidoreductase, aldo/keto
reductase family - Thermotoga maritima
Length = 286
Score = 46.0 bits (104), Expect = 0.002
Identities = 39/117 (33%), Positives = 57/117 (48%), Gaps = 4/117 (3%)
Frame = +3
Query: 342 KKFSEGL-KRESIFITTKLWNSYHEREQVIPALRKSLXKSQLGIRRPVFDSLAHSYV*ER 518
+ EG+ +RE +F+TTKLW S E A KSL K QL Y+ +
Sbjct: 62 RAIDEGIVRREELFVTTKLWVSDVGYESTKKAFEKSLKKLQL------------EYI-DL 108
Query: 519 YLARHVDFLD---TWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGLEKPSALQIE 680
YL H F D W+ M + K GL ++IG+SNF +++ ++ P+ QIE
Sbjct: 109 YLI-HQPFGDVHCAWKAMEEMYKDGLVRAIGVSNFYPDRLMDLMVHHEIVPAVNQIE 164
Score = 37.5 bits (83), Expect = 0.53
Identities = 25/71 (35%), Positives = 38/71 (53%)
Frame = +2
Query: 137 VPTLQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIE 316
VP + L++G +P++ G + P K TE+ V A++ GY IDTA Y E
Sbjct: 3 VPKVTLNNGVEMPILGYGVF--QIPPEK-------TEECVYEAIKVGYRLIDTAASYMNE 53
Query: 317 DQVGRALXQEI 349
+ VGRA+ + I
Sbjct: 54 EGVGRAIKRAI 64
>UniRef50_Q1IN88 Cluster: Aldehyde reductase; n=5; Bacteria|Rep:
Aldehyde reductase - Acidobacteria bacterium (strain
Ellin345)
Length = 313
Score = 46.0 bits (104), Expect = 0.002
Identities = 31/118 (26%), Positives = 54/118 (45%), Gaps = 11/118 (9%)
Frame = +3
Query: 360 LKRESIFITTKLWNSYHEREQVIPALRKSLXKSQLGIR-----------RPVFDSLAHSY 506
+ RE IF+TTKLWN+ H E+V PA SL + L +P +
Sbjct: 75 IAREEIFVTTKLWNTNHRPERVEPAFEASLDRLGLDYLDLYLIHTPFAFQPGDEQDPRDQ 134
Query: 507 V*ERYLARHVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGLEKPSALQIE 680
V +TW + + G ++IG+S+ + +++ I ++ KP+ +Q+E
Sbjct: 135 NGSVIYDEGVTLRETWSALENLVDRGRCRAIGLSDISMDRLAPIYEAARIKPAVVQVE 192
>UniRef50_Q7XY49 Cluster: Mannose 6-phosphate reductase; n=1;
Griffithsia japonica|Rep: Mannose 6-phosphate reductase
- Griffithsia japonica (Red alga)
Length = 174
Score = 46.0 bits (104), Expect = 0.002
Identities = 33/80 (41%), Positives = 39/80 (48%)
Frame = +2
Query: 143 TLQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQ 322
T L SG +P+ GTW K V +TEQAV AL AGY HID A Y E
Sbjct: 5 TATLQSGAKMPLNGFGTW-----KASV----EETEQAVTAALRAGYRHIDCAAVYWNEAA 55
Query: 323 VGRALXQEILRRT*KRIYLY 382
VG A+ + I KR L+
Sbjct: 56 VGTAISKAISGGVVKREDLF 75
Score = 40.3 bits (90), Expect(2) = 0.006
Identities = 18/43 (41%), Positives = 30/43 (69%), Gaps = 1/43 (2%)
Frame = +3
Query: 339 TKKFSEGL-KRESIFITTKLWNSYHEREQVIPALRKSLXKSQL 464
+K S G+ KRE +FIT+K+WN+ H ++V+ + R+SL Q+
Sbjct: 61 SKAISGGVVKREDLFITSKVWNTCHATDKVVDSCRQSLKDHQV 103
Score = 23.0 bits (47), Expect(2) = 0.006
Identities = 12/39 (30%), Positives = 20/39 (51%)
Frame = +3
Query: 564 IDAKKLGLTKSIGISNFNQEQIQRIIDSGLEKPSALQIE 680
+D L L + IG+SN++ + ++ KPS Q E
Sbjct: 103 VDYFDLFLVRDIGVSNYSVALLVDTLNYARIKPSVNQCE 141
>UniRef50_Q0CK00 Cluster: Predicted protein; n=1; Aspergillus
terreus NIH2624|Rep: Predicted protein - Aspergillus
terreus (strain NIH 2624)
Length = 292
Score = 46.0 bits (104), Expect = 0.002
Identities = 35/109 (32%), Positives = 55/109 (50%), Gaps = 1/109 (0%)
Frame = +3
Query: 357 GLKRESIFITTKLWNSYHEREQVIPALRKSLXKSQLGIRRPVFDSLAHS-YV*ERYLARH 533
G+ RE +FITTK+ + + V AL SL + QL V L H+ YV +
Sbjct: 73 GIPREQLFITTKVLEGWKD---VPGALDASLERLQLDY---VDLYLLHNPYV----IPNL 122
Query: 534 VDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGLEKPSALQIE 680
D W+G+ K G +SIG+SNF + ++ I+++ P+ Q+E
Sbjct: 123 TDIQSAWKGLEAVKATGKARSIGVSNFQRNHLEAILETCSVVPAINQLE 171
Score = 39.9 bits (89), Expect = 0.099
Identities = 22/73 (30%), Positives = 33/73 (45%)
Frame = +2
Query: 140 PTLQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIED 319
P L L G +P++ GT + + + ALE G+ HID A YG E
Sbjct: 4 PALSLKDGNLVPILGFGTGTAWYKDDPNDPTNPELIEVLKAALEKGFHHIDAADSYGTER 63
Query: 320 QVGRALXQEILRR 358
+VG A+ + + R
Sbjct: 64 EVGIAIRESGIPR 76
>UniRef50_P28475 Cluster: NADP-dependent D-sorbitol-6-phosphate
dehydrogenase; n=71; Magnoliophyta|Rep: NADP-dependent
D-sorbitol-6-phosphate dehydrogenase - Malus domestica
(Apple) (Malus sylvestris)
Length = 310
Score = 46.0 bits (104), Expect = 0.002
Identities = 41/126 (32%), Positives = 56/126 (44%), Gaps = 15/126 (11%)
Frame = +3
Query: 348 FSEGL-KRESIFITTKLWNSYHEREQVIPALRKSLXKSQLG------IRRPV------FD 488
F GL KRE +FITTK+WNS H V+ A + SL K Q+ + P+
Sbjct: 62 FKTGLVKREELFITTKIWNSDH--GHVVEACKNSLEKLQIDYLDLYLVHYPMPTKHNAIG 119
Query: 489 SLAHSYV*ERYLARHV--DFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGLEKP 662
A ++ L V TW GM LGL +SIG+SN+ + + KP
Sbjct: 120 KTASLLGEDKVLDIDVTISLQQTWEGMEKTVSLGLVRSIGLSNYELFLTRDCLAYSKIKP 179
Query: 663 SALQIE 680
+ Q E
Sbjct: 180 AVSQFE 185
Score = 40.3 bits (90), Expect = 0.075
Identities = 25/80 (31%), Positives = 39/80 (48%)
Frame = +2
Query: 143 TLQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQ 322
T+ LSSG +PV+ LG W + ++ ++ ++ A++ GY H D A Y E
Sbjct: 3 TVTLSSGYEMPVIGLGLWRLEK---------DELKEVILNAIKIGYRHFDCAAHYKSEAD 53
Query: 323 VGRALXQEILRRT*KRIYLY 382
VG AL + KR L+
Sbjct: 54 VGEALAEAFKTGLVKREELF 73
>UniRef50_Q568D7 Cluster: Zgc:110366; n=7; Euteleostomi|Rep:
Zgc:110366 - Danio rerio (Zebrafish) (Brachydanio rerio)
Length = 289
Score = 45.6 bits (103), Expect = 0.002
Identities = 29/77 (37%), Positives = 44/77 (57%), Gaps = 1/77 (1%)
Frame = +2
Query: 131 LIVPTLQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYAL-EAGYTHIDTAYKY 307
L P + L +G NIP++ LGT H + +AV+YAL E G HIDTA +Y
Sbjct: 11 LSCPAVPLHNGLNIPILGLGT--SH--------YGGYSHEAVLYALQECGIRHIDTAKRY 60
Query: 308 GIEDQVGRALXQEILRR 358
G E+ +G+A+ + ++R
Sbjct: 61 GCEEALGKAVTESGVQR 77
Score = 45.2 bits (102), Expect = 0.003
Identities = 37/131 (28%), Positives = 60/131 (45%), Gaps = 3/131 (2%)
Frame = +3
Query: 297 HTNMESRTKWEGPXTKKFSE-GLKRESIFITTKLWNSYHEREQVIPALRKSLXKSQLGIR 473
H + R E K +E G++RE +++TTKLW + + A R S +++LG+
Sbjct: 53 HIDTAKRYGCEEALGKAVTESGVQREELWVTTKLWPGDYGYQSTKQACRDS--RARLGV- 109
Query: 474 RPVFDSLAHSYV*ERYLARHVDF--LDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDS 647
D + R L+TWR + + GL ++IG+SNF + + DS
Sbjct: 110 -DYLDLYLMHWPDSMVPGRSSQEVRLETWRALEELYDEGLCRAIGVSNFLIPHLNELKDS 168
Query: 648 GLEKPSALQIE 680
G P Q+E
Sbjct: 169 GGIVPHVNQVE 179
>UniRef50_A5DRJ6 Cluster: Putative uncharacterized protein; n=4;
Pichia guilliermondii|Rep: Putative uncharacterized
protein - Pichia guilliermondii (Yeast) (Candida
guilliermondii)
Length = 287
Score = 45.6 bits (103), Expect = 0.002
Identities = 34/108 (31%), Positives = 56/108 (51%), Gaps = 2/108 (1%)
Frame = +3
Query: 363 KRESIFITTKLWNSYHEREQVIPALRKSLXKSQLGIRRPVFDSLAHSYV*ERYLARHVDF 542
KRE + TTK+ N ++ +L++SL K ++ + L + L+
Sbjct: 75 KREDVLYTTKITNLNQGYDRTWRSLKESLNK----VKHLEYIDLVLIH---DPLSDKKTR 127
Query: 543 LDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIID-SGLE-KPSALQIE 680
++TW+ + +A G+ KSIG+SNF + IQ + D GL+ KP QIE
Sbjct: 128 IETWKALQEAVDSGMVKSIGVSNFGKHHIQELYDWEGLKYKPIVNQIE 175
>UniRef50_Q88TV9 Cluster: Oxidoreductase; n=4; Lactobacillus|Rep:
Oxidoreductase - Lactobacillus plantarum
Length = 288
Score = 45.2 bits (102), Expect = 0.003
Identities = 29/68 (42%), Positives = 38/68 (55%), Gaps = 2/68 (2%)
Frame = +2
Query: 140 PTLQLSSGGNIPVVALGTWLGHRPKGKVVQVTND--TEQAVIYALEAGYTHIDTAYKYGI 313
PT+ L+ G IP + GT+ Q+ +D T QAV AL GY HIDTA Y
Sbjct: 5 PTITLNDGRAIPAIGFGTF----------QIPDDGSTYQAVKEALVIGYRHIDTAVAYFN 54
Query: 314 EDQVGRAL 337
ED+VG+A+
Sbjct: 55 EDEVGQAI 62
Score = 38.7 bits (86), Expect = 0.23
Identities = 31/110 (28%), Positives = 51/110 (46%), Gaps = 2/110 (1%)
Frame = +3
Query: 357 GLKRESIFITTKLWNSYHEREQVIPALRKSLXKSQLGIRRPVFDSLAHSYV*ERYLAR-- 530
G+ R+ I++T+KLW + + A+ +SL K +L Y+ + YL
Sbjct: 66 GIPRDQIWVTSKLWLQDYGFDAASRAIDRSLTKLRL------------DYI-DLYLIHQP 112
Query: 531 HVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGLEKPSALQIE 680
+ D W+ M A+K G KSIG+SN Q+ + P+ Q+E
Sbjct: 113 YGDVPGAWQAMEAAQKAGKLKSIGVSNMTPTLWQKFVPQFETIPAVNQVE 162
>UniRef50_Q1RFP0 Cluster: 2,5-diketo-D-gluconic acid reductase A;
n=21; Bacteria|Rep: 2,5-diketo-D-gluconic acid reductase
A - Escherichia coli (strain UTI89 / UPEC)
Length = 294
Score = 45.2 bits (102), Expect = 0.003
Identities = 37/112 (33%), Positives = 54/112 (48%), Gaps = 2/112 (1%)
Frame = +3
Query: 351 SEGL-KRESIFITTKLWNSYHEREQVIPA-LRKSLXKSQLGIRRPVFDSLAHSYV*ERYL 524
SEGL RE +FIT+KLW + + A + SL KS L FD Y+ + +
Sbjct: 69 SEGLCTREELFITSKLWVQDMLNQDIAAAGIEASLKKSGL----EYFDL----YLLHQAM 120
Query: 525 ARHVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGLEKPSALQIE 680
D+ WR + DA + G K+IG+SNF + ++ KP Q+E
Sbjct: 121 R---DYFSAWRALEDAYEEGKLKAIGVSNFYPHVLANFCETVRVKPMVNQVE 169
Score = 37.5 bits (83), Expect = 0.53
Identities = 21/45 (46%), Positives = 28/45 (62%), Gaps = 2/45 (4%)
Frame = +2
Query: 221 VVQVTNDT--EQAVIYALEAGYTHIDTAYKYGIEDQVGRALXQEI 349
V QVT+ +Q+V+ A+ GY IDTA YG ED VG A+ + I
Sbjct: 24 VFQVTDKDVCKQSVLNAIRTGYRLIDTAAVYGNEDAVGEAVREAI 68
>UniRef50_A6ESC0 Cluster: ARA1; n=1; unidentified eubacterium
SCB49|Rep: ARA1 - unidentified eubacterium SCB49
Length = 280
Score = 45.2 bits (102), Expect = 0.003
Identities = 29/110 (26%), Positives = 51/110 (46%), Gaps = 3/110 (2%)
Frame = +3
Query: 360 LKRESIFITTKLWNSYHEREQVIPALRKSLXKSQLG---IRRPVFDSLAHSYV*ERYLAR 530
+ R+ +F+T+K+WN E + A ++ QL + + + AH + + L
Sbjct: 65 IDRKDLFVTSKVWNEQRGYENTLKAFDNTINDLQLDYLDLYLIHWPAAAHQFENWKQLNN 124
Query: 531 HVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGLEKPSALQIE 680
DTW M K G K++G+SNF + + ++ KP+ QIE
Sbjct: 125 -----DTWSAMEKLYKDGKIKALGVSNFMEHHLTPLLQHATIKPTVNQIE 169
Score = 35.9 bits (79), Expect = 1.6
Identities = 23/70 (32%), Positives = 34/70 (48%)
Frame = +2
Query: 149 QLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQVG 328
+L++ NIP + GTW P G+ A+ A++AGY HID A Y E VG
Sbjct: 6 KLNNNINIPAIGFGTW--QTPDGQTAI------NAIKTAIDAGYKHIDAAAIYKNEKGVG 57
Query: 329 RALXQEILRR 358
+ + + R
Sbjct: 58 LGIKEANIDR 67
>UniRef50_Q01HB5 Cluster: OSIGBa0136O08-OSIGBa0153H12.9 protein;
n=4; Oryza sativa|Rep: OSIGBa0136O08-OSIGBa0153H12.9
protein - Oryza sativa (Rice)
Length = 337
Score = 45.2 bits (102), Expect = 0.003
Identities = 37/116 (31%), Positives = 58/116 (50%), Gaps = 11/116 (9%)
Frame = +3
Query: 366 RESIFITTKLWNSYHEREQVIPALRKSLXKSQLG------IRRPVFDSL--AHSYV*ERY 521
R +F+TTKL + +V+ ALR+SL + L I PV A +
Sbjct: 90 RGELFVTTKLSMADAHPPRVVAALRESLSRLGLDYVDLFLIHWPVAIGKKDAAGELTWDD 149
Query: 522 LARHV---DFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGLEKPSALQIE 680
L+R + D WRGM + +LGL +SIG+SNF+ ++ R++ P+ Q+E
Sbjct: 150 LSRGLVPFDMEGVWRGMEECHRLGLARSIGVSNFSAAKMSRLLALAAVPPAVNQVE 205
Score = 42.3 bits (95), Expect = 0.018
Identities = 25/76 (32%), Positives = 37/76 (48%)
Frame = +2
Query: 122 SADLIVPTLQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAY 301
+A VP + L+SG +PV+ GT P D + +A+ GY H+DTA
Sbjct: 15 AAATAVPCVTLNSGHAMPVLGFGTGSSTPPA--------DLAATIAHAVRLGYRHLDTAA 66
Query: 302 KYGIEDQVGRALXQEI 349
YG E VG A+ + +
Sbjct: 67 VYGTEGAVGAAVAEAV 82
Score = 40.7 bits (91), Expect = 0.056
Identities = 18/37 (48%), Positives = 25/37 (67%), Gaps = 1/37 (2%)
Frame = +1
Query: 448 LXNLNLEYVDLYLIHWPIAMFENDTLLD-TWTFWTRG 555
L L L+YVDL+LIHWP+A+ + D + TW +RG
Sbjct: 117 LSRLGLDYVDLFLIHWPVAIGKKDAAGELTWDDLSRG 153
>UniRef50_Q76L37 Cluster: Conjugated polyketone reductase C1; n=3;
Saccharomycetales|Rep: Conjugated polyketone reductase
C1 - Candida parapsilosis (Yeast)
Length = 304
Score = 45.2 bits (102), Expect = 0.003
Identities = 35/116 (30%), Positives = 57/116 (49%), Gaps = 8/116 (6%)
Frame = +3
Query: 357 GLKRESIFITTKL------WNSYHEREQ-VIPALRKSLXKSQLGIRRPVFDSLAHSYV*E 515
GL R+ +FIT K ++ H + Q AL+ L LG+ + Y+ E
Sbjct: 74 GLNRKDVFITDKYNSGNHTYDGKHSKHQNPYNALKADL--EDLGLEYVDLYLIHFPYISE 131
Query: 516 RYLARHVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGLEK-PSALQIE 680
+ + D ++ WR + AK GL ++IG+SNF E ++ I+D+ + P QIE
Sbjct: 132 K--SHGFDLVEAWRYLERAKNEGLARNIGVSNFTIENLKSILDANTDSIPVVNQIE 185
Score = 39.5 bits (88), Expect = 0.13
Identities = 27/74 (36%), Positives = 38/74 (51%), Gaps = 4/74 (5%)
Frame = +2
Query: 149 QLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVI----YALEAGYTHIDTAYKYGIE 316
+LS+G IP VA GT + +G ND ++ +I AL +G+ HID A YG
Sbjct: 9 KLSNGNKIPAVAFGTGTKYFKRGH-----NDLDKQLIGTLELALRSGFRHIDGAEIYGTN 63
Query: 317 DQVGRALXQEILRR 358
++G AL L R
Sbjct: 64 KEIGIALKNVGLNR 77
>UniRef50_Q4WP69 Cluster: Aldehyde reductase, putative; n=1;
Aspergillus fumigatus|Rep: Aldehyde reductase, putative
- Aspergillus fumigatus (Sartorya fumigata)
Length = 350
Score = 45.2 bits (102), Expect = 0.003
Identities = 35/123 (28%), Positives = 60/123 (48%), Gaps = 15/123 (12%)
Frame = +3
Query: 357 GLKRESIFITTKLWNSYHEREQVIPALRKSLXKSQ-----LGIRRPVFDSLAHSYV---- 509
G+ RE IF+T+KLWN++H V AL K++ Q L + P+ + H+Y
Sbjct: 97 GVPREGIFLTSKLWNTHHHPSHVEEALDKTVKDLQTNYLDLYLLYPL-GHILHTYQRHIP 155
Query: 510 -----*ERYLARHVDFLDTWRGMIDAKKLGLTKSIGISN-FNQEQIQRIIDSGLEKPSAL 671
+R+ + DTW G +S+G+SN F E+++ ++++ P+
Sbjct: 156 ASRPGHKRFRLVDIPIGDTWAAREKLVNAGKIRSLGVSNLFTIEKMEELLNTADIPPAVN 215
Query: 672 QIE 680
QIE
Sbjct: 216 QIE 218
>UniRef50_Q043M4 Cluster: Aldo/keto reductase of diketogulonate
reductase family; n=2; Lactobacillus|Rep: Aldo/keto
reductase of diketogulonate reductase family -
Lactobacillus gasseri (strain ATCC 33323 / DSM 20243)
Length = 273
Score = 44.8 bits (101), Expect = 0.003
Identities = 37/110 (33%), Positives = 54/110 (49%)
Frame = +3
Query: 351 SEGLKRESIFITTKLWNSYHEREQVIPALRKSLXKSQLGIRRPVFDSLAHSYV*ERYLAR 530
+ GL R+ +FITTK +E ++ L +SL + +G+ FD V +
Sbjct: 60 ASGLNRDEVFITTKTMTDGYEDTKI--GLDESLRR--IGL--DYFD-----LVLIHWPMG 108
Query: 531 HVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGLEKPSALQIE 680
H +DTW + A K G T++IGISNFN Q +I +P QIE
Sbjct: 109 H--DIDTWHALEAAYKAGKTRAIGISNFNSRQTLDLIHQSSVRPMVDQIE 156
Score = 37.5 bits (83), Expect = 0.53
Identities = 20/41 (48%), Positives = 24/41 (58%)
Frame = +2
Query: 236 NDTEQAVIYALEAGYTHIDTAYKYGIEDQVGRALXQEILRR 358
+ T+QAV+ A E GY IDTA Y E QVG A+ L R
Sbjct: 25 DQTKQAVLSAFEEGYRLIDTAQYYQNEQQVGEAVKASGLNR 65
>UniRef50_Q03U37 Cluster: Aldo/keto reductase of diketogulonate
reductase family; n=5; Lactobacillus|Rep: Aldo/keto
reductase of diketogulonate reductase family -
Lactobacillus brevis (strain ATCC 367 / JCM 1170)
Length = 282
Score = 44.8 bits (101), Expect = 0.003
Identities = 33/108 (30%), Positives = 49/108 (45%)
Frame = +3
Query: 357 GLKRESIFITTKLWNSYHEREQVIPALRKSLXKSQLGIRRPVFDSLAHSYV*ERYLARHV 536
GL RE +F+T+K+ +Q + A+ SL + Q + L H V E
Sbjct: 69 GLPREGLFLTSKVAEIVQGYDQTMKAVEGSLKRLQTDYLDLL---LIHWPVREH------ 119
Query: 537 DFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGLEKPSALQIE 680
F DTWR + K G KSIG+SN+ ++ + E P Q+E
Sbjct: 120 -FFDTWRALEQLKADGQVKSIGVSNYTIAHLELLATKAKEMPVVNQVE 166
Score = 34.7 bits (76), Expect = 3.7
Identities = 26/70 (37%), Positives = 37/70 (52%)
Frame = +2
Query: 134 IVPTLQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGI 313
I T +L+ G +PV+ GT+L + Q T +T A+ A +AGY DTA Y
Sbjct: 6 ITATRKLADGRQMPVMGFGTYLLND------QPTMNT--AIQTAWDAGYRMFDTAMLYRN 57
Query: 314 EDQVGRALXQ 343
ED +G A+ Q
Sbjct: 58 EDILGPAIQQ 67
>UniRef50_A3VRL4 Cluster: Putative uncharacterized protein; n=1;
Parvularcula bermudensis HTCC2503|Rep: Putative
uncharacterized protein - Parvularcula bermudensis
HTCC2503
Length = 278
Score = 44.8 bits (101), Expect = 0.003
Identities = 36/118 (30%), Positives = 58/118 (49%), Gaps = 5/118 (4%)
Frame = +3
Query: 342 KKFSEGLK-----RESIFITTKLWNSYHEREQVIPALRKSLXKSQLGIRRPVFDSLAHSY 506
KK EG+K R+ +F+TTK+WN ++ + A+ +SL + L + L H
Sbjct: 51 KKVGEGIKDSGIPRDELFVTTKIWNEDIQKGRHSEAVDESLDRLGLDYVNLI---LLHWP 107
Query: 507 V*ERYLARHVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGLEKPSALQIE 680
+ + +A V L + K+ G K IGISN+NQ Q + + E +A+Q E
Sbjct: 108 INDMPIADQVGPL------AEIKRSGRAKLIGISNYNQAQFLEAVSASEEPLAAIQCE 159
>UniRef50_Q68ST9 Cluster: Reductase AKOR2; n=2; Pleurotus
djamor|Rep: Reductase AKOR2 - Pleurotus djamor
Length = 306
Score = 44.8 bits (101), Expect = 0.003
Identities = 24/73 (32%), Positives = 39/73 (53%)
Frame = +2
Query: 140 PTLQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIED 319
P + L++G +P +ALG W G + + ++ + AL++GY HIDTA Y E
Sbjct: 5 PPIVLNTGARMPALALGGWAGLTEEERT-----QAKEWFLTALKSGYRHIDTAQIYYTEK 59
Query: 320 QVGRALXQEILRR 358
VG A+ + + R
Sbjct: 60 SVGNAIRESGIPR 72
Score = 36.3 bits (80), Expect = 1.2
Identities = 15/41 (36%), Positives = 25/41 (60%)
Frame = +1
Query: 400 IPTTRESK*SQR*GSPLXNLNLEYVDLYLIHWPIAMFENDT 522
+P S+ ++ L NL EY+DLYL+H+P +F ++T
Sbjct: 81 LPWNHHSRVAESFQKSLENLGTEYIDLYLVHFPQRVFYDET 121
>UniRef50_P38115 Cluster: D-arabinose dehydrogenase [NAD(P)+] heavy
chain; n=3; Saccharomycetaceae|Rep: D-arabinose
dehydrogenase [NAD(P)+] heavy chain - Saccharomyces
cerevisiae (Baker's yeast)
Length = 344
Score = 44.8 bits (101), Expect = 0.003
Identities = 27/64 (42%), Positives = 38/64 (59%)
Frame = +2
Query: 152 LSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQVGR 331
L++G IP + LGT P K+ + T+QAV A++AGY HIDTA+ Y E VG
Sbjct: 27 LNNGVRIPALGLGT---ANPHEKLAE----TKQAVKAAIKAGYRHIDTAWAYETEPFVGE 79
Query: 332 ALXQ 343
A+ +
Sbjct: 80 AIKE 83
>UniRef50_Q927P9 Cluster: Lin2739 protein; n=12; Bacteria|Rep:
Lin2739 protein - Listeria innocua
Length = 283
Score = 44.4 bits (100), Expect = 0.005
Identities = 24/65 (36%), Positives = 37/65 (56%)
Frame = +2
Query: 143 TLQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQ 322
T++L++G +P++ GT+ + + EQAV A+ AGY HIDTA Y E+
Sbjct: 3 TVKLNNGIEVPILGFGTYQ--------ITDAGEAEQAVKEAIAAGYRHIDTAQSYMNEEA 54
Query: 323 VGRAL 337
VGR +
Sbjct: 55 VGRGI 59
Score = 35.9 bits (79), Expect = 1.6
Identities = 29/110 (26%), Positives = 51/110 (46%)
Frame = +3
Query: 351 SEGLKRESIFITTKLWNSYHEREQVIPALRKSLXKSQLGIRRPVFDSLAHSYV*ERYLAR 530
+ G+ R+ +FITTK+W + V+ + +SL + LG+ D + + + Y
Sbjct: 61 ASGVDRKELFITTKIWVENVSYKGVMSSFDRSLKR--LGL-----DYIDLLLIHQPYN-- 111
Query: 531 HVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGLEKPSALQIE 680
D W M + + G K+IG+SNF +++ + P QIE
Sbjct: 112 --DVYGAWMAMEELQAQGKIKAIGVSNFGVDRVVDLAAFNDITPQVNQIE 159
>UniRef50_Q8EUH6 Cluster: Oxidoreductase; n=1; Mycoplasma
penetrans|Rep: Oxidoreductase - Mycoplasma penetrans
Length = 285
Score = 44.4 bits (100), Expect = 0.005
Identities = 37/110 (33%), Positives = 52/110 (47%), Gaps = 3/110 (2%)
Frame = +3
Query: 360 LKRESIFITTKLWNSYHEREQVIPALRKSLXKSQLGIRRPVFDSLAHSYV*ERYLARHVD 539
+KRE IFITTK+W S + + ++ KSL K Q V L H D
Sbjct: 64 IKREDIFITTKVWISNYGYNNTMYSISKSLKKLQTNYIDLV---LLHQ--------PFGD 112
Query: 540 FLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGLE---KPSALQIE 680
+ W+ + K G+ K+IG+SNF + R++D L KP QIE
Sbjct: 113 YYSAWKALEVLYKKGIVKAIGVSNF---EADRLVDFCLHVDVKPVINQIE 159
>UniRef50_Q4V008 Cluster: Oxidoreductase; n=4; Proteobacteria|Rep:
Oxidoreductase - Xanthomonas campestris pv. campestris
(strain 8004)
Length = 267
Score = 44.4 bits (100), Expect = 0.005
Identities = 33/109 (30%), Positives = 56/109 (51%), Gaps = 1/109 (0%)
Frame = +3
Query: 357 GLKRESIFITTKLWNSYHEREQVIPALRKSLXKSQLGIRRPVFDSLAHSYV*ERYLARHV 536
G+ R+ +F+TTK+W R+ + P+L++SL K LG D + + + V
Sbjct: 53 GVPRDQLFVTTKIWVDRFSRDTLQPSLQESLRK--LGT-----DYVDLTLIHWPSPKDQV 105
Query: 537 DFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIID-SGLEKPSALQIE 680
+ + DAK GLT++IG+SNF ++ I+ G + + QIE
Sbjct: 106 PMREYLEALADAKAQGLTRAIGVSNFTIALTRQAIEILGADAIATNQIE 154
>UniRef50_P70883 Cluster: AkrI; n=1; Butyrivibrio fibrisolvens|Rep:
AkrI - Butyrivibrio fibrisolvens
Length = 172
Score = 44.4 bits (100), Expect = 0.005
Identities = 27/94 (28%), Positives = 43/94 (45%)
Frame = +3
Query: 363 KRESIFITTKLWNSYHEREQVIPALRKSLXKSQLGIRRPVFDSLAHSYV*ERYLARHVDF 542
KRE IF+T+K W + ++ + A K++ + Q+ SY +
Sbjct: 73 KREDIFVTSKAWKTELGYDKTLAAFEKTMNEMQMDYLDLYLVHWPASYAFDDDWEN--TN 130
Query: 543 LDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIID 644
TW+ M + K G K+IG+SNF + IID
Sbjct: 131 RQTWKAMTEIYKSGRVKAIGVSNFLTHHLDTIID 164
>UniRef50_A4RQH8 Cluster: Predicted protein; n=2; Ostreococcus|Rep:
Predicted protein - Ostreococcus lucimarinus CCE9901
Length = 337
Score = 44.4 bits (100), Expect = 0.005
Identities = 30/72 (41%), Positives = 36/72 (50%)
Frame = +2
Query: 155 SSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQVGRA 334
++G IP V LGTW RP N+ AV AL AGY H+D A Y E +VG A
Sbjct: 11 ANGLRIPRVGLGTWKA-RP--------NEVRDAVRDALGAGYAHVDCAAAYANESEVGEA 61
Query: 335 LXQEILRRT*KR 370
L + R KR
Sbjct: 62 LREAFERGDAKR 73
Score = 33.5 bits (73), Expect = 8.6
Identities = 12/19 (63%), Positives = 16/19 (84%)
Frame = +1
Query: 448 LXNLNLEYVDLYLIHWPIA 504
L +L + Y+DLYLIHWP+A
Sbjct: 100 LNDLGVGYLDLYLIHWPVA 118
>UniRef50_Q5TNP1 Cluster: ENSANGP00000029046; n=2; Culicidae|Rep:
ENSANGP00000029046 - Anopheles gambiae str. PEST
Length = 331
Score = 44.4 bits (100), Expect = 0.005
Identities = 27/65 (41%), Positives = 38/65 (58%)
Frame = +2
Query: 143 TLQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQ 322
T +L++G +IP+ GT+ H + + QV + YALEAGY HIDTA Y E+
Sbjct: 33 TFKLNTGFDIPLAGFGTYQIHGQE-LIYQVLD-------YALEAGYRHIDTAVVYRNEEY 84
Query: 323 VGRAL 337
+G AL
Sbjct: 85 IGTAL 89
Score = 33.5 bits (73), Expect = 8.6
Identities = 12/17 (70%), Positives = 14/17 (82%)
Frame = +1
Query: 448 LXNLNLEYVDLYLIHWP 498
L NL +Y+DLYLIHWP
Sbjct: 128 LANLQTDYLDLYLIHWP 144
>UniRef50_Q6C2L0 Cluster: Yarrowia lipolytica chromosome F of strain
CLIB122 of Yarrowia lipolytica; n=3; Yarrowia
lipolytica|Rep: Yarrowia lipolytica chromosome F of
strain CLIB122 of Yarrowia lipolytica - Yarrowia
lipolytica (Candida lipolytica)
Length = 324
Score = 44.4 bits (100), Expect = 0.005
Identities = 38/123 (30%), Positives = 61/123 (49%), Gaps = 14/123 (11%)
Frame = +3
Query: 354 EGLKRESIFITTKLWNSYHER-EQVIPALRKSLXKSQLG---IRRPVF------DSLAHS 503
E +KRE++F+TTK+W +++ R + + K L + + PV D A
Sbjct: 66 ELVKRENLFVTTKVWPTFYNRVSESLDISLKDLSLDYVDLLLVHWPVSLLADSDDPRAIY 125
Query: 504 YV*ERYLARHVDFLDTW---RGMIDAKKL-GLTKSIGISNFNQEQIQRIIDSGLEKPSAL 671
V R+ D LD W I+ +KL G TKSIG+SN ++ ++R++D P+
Sbjct: 126 LVNTDGSVRYSDSLDDWITTYKQIEEEKLSGRTKSIGVSNVSEVYLKRLLDQVKTVPAVN 185
Query: 672 QIE 680
Q E
Sbjct: 186 QFE 188
Score = 41.9 bits (94), Expect = 0.024
Identities = 29/79 (36%), Positives = 43/79 (54%), Gaps = 4/79 (5%)
Frame = +2
Query: 134 IVPTLQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGI 313
I + +L+ G +IP + LGT G V E+ V A++ GY HIDTA+ YG
Sbjct: 3 ITDSFKLNDGHSIPALGLGT----ASDGNV-------EEVVYAAIKNGYRHIDTAFIYGS 51
Query: 314 EDQVG----RALXQEILRR 358
E VG RA+ +E+++R
Sbjct: 52 EVDVGKGIKRAIDEELVKR 70
Score = 33.9 bits (74), Expect = 6.5
Identities = 11/20 (55%), Positives = 18/20 (90%)
Frame = +1
Query: 448 LXNLNLEYVDLYLIHWPIAM 507
L +L+L+YVDL L+HWP+++
Sbjct: 95 LKDLSLDYVDLLLVHWPVSL 114
>UniRef50_A2QL02 Cluster: Putative frameshift; n=1; Aspergillus
niger|Rep: Putative frameshift - Aspergillus niger
Length = 357
Score = 44.4 bits (100), Expect = 0.005
Identities = 33/123 (26%), Positives = 56/123 (45%), Gaps = 15/123 (12%)
Frame = +3
Query: 357 GLKRESIFITTKLW-NSYHEREQVIPALRKSLXKSQLGIRRPVFDSLAHSY--------- 506
G+ RE IF+ TKLW N +H + + +++ S + P D L Y
Sbjct: 95 GVPREEIFLGTKLWCNDFHPDD-----VERAVDDSLRDLYTPYVDLLLMHYPCTFKRGED 149
Query: 507 -----V*ERYLARHVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGLEKPSAL 671
R + F+DTWR + K G ++IG+SNF++ +I+ ++ P+
Sbjct: 150 RFPRDAEGRMIHGETTFVDTWRALEKVVKTGKVRAIGVSNFSKGEIETLLRETSTVPAVH 209
Query: 672 QIE 680
Q+E
Sbjct: 210 QME 212
Score = 38.3 bits (85), Expect = 0.30
Identities = 23/65 (35%), Positives = 33/65 (50%)
Frame = +2
Query: 143 TLQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQ 322
T L++G IP + +GT+ Q + E+ V L+ G IDTA YG+E Q
Sbjct: 37 TYTLNTGAKIPALGVGTF----------QDPDSQEETVCQVLQRGMRLIDTARVYGVEQQ 86
Query: 323 VGRAL 337
VGR +
Sbjct: 87 VGRGI 91
>UniRef50_UPI00006CCCD7 Cluster: oxidoreductase, aldo/keto reductase
family protein; n=1; Tetrahymena thermophila SB210|Rep:
oxidoreductase, aldo/keto reductase family protein -
Tetrahymena thermophila SB210
Length = 323
Score = 44.0 bits (99), Expect = 0.006
Identities = 31/116 (26%), Positives = 56/116 (48%), Gaps = 5/116 (4%)
Frame = +3
Query: 348 FSEG-LKRESIFITTKLWNSYHEREQVIPALRKSLXKSQLGIRRPVFDSLAHSYV*ERY- 521
F +G KRE +FITTKL+ + +++ ++ SL + Q + + V +
Sbjct: 79 FQQGKYKREDVFITTKLF-PFKIEKKIKEVVQNSLDQLQTSYIDLYLIQWSFTPVLTNFD 137
Query: 522 ---LARHVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGLEKPSALQIE 680
H + WR + + +LG+ +SIG++NFN + + ++ KP QIE
Sbjct: 138 GSVAVNHRPIHEVWRELEECVELGMIRSIGVANFNCQMVLDLLSYAKIKPVVNQIE 193
Score = 35.9 bits (79), Expect = 1.6
Identities = 22/64 (34%), Positives = 39/64 (60%), Gaps = 1/64 (1%)
Frame = +2
Query: 146 LQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIY-ALEAGYTHIDTAYKYGIEDQ 322
+QL++G +P++ LGT +P V +VT + ++ AL+ GY + DTA +Y E +
Sbjct: 15 VQLNNGYKMPLLGLGT----QPYDIVTRVTVEEMTTLLSNALDFGYRNFDTAKQYRNEVE 70
Query: 323 VGRA 334
+G+A
Sbjct: 71 IGQA 74
>UniRef50_Q5BLA6 Cluster: Zgc:110782; n=2; Danio rerio|Rep:
Zgc:110782 - Danio rerio (Zebrafish) (Brachydanio rerio)
Length = 287
Score = 44.0 bits (99), Expect = 0.006
Identities = 26/71 (36%), Positives = 41/71 (57%)
Frame = +2
Query: 131 LIVPTLQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYG 310
+IVP+++L SG +P++ LGT+ +Q +Q+V AL+AGY DTA YG
Sbjct: 1 MIVPSVRLMSGTQMPLLGLGTYK--------LQDHEQLKQSVSCALQAGYRAFDTAAVYG 52
Query: 311 IEDQVGRALXQ 343
E +G+ L +
Sbjct: 53 NEAHLGQVLKE 63
Score = 33.5 bits (73), Expect = 8.6
Identities = 12/17 (70%), Positives = 14/17 (82%)
Frame = +1
Query: 448 LXNLNLEYVDLYLIHWP 498
L L+ EY+DLYLIHWP
Sbjct: 98 LEQLDCEYIDLYLIHWP 114
>UniRef50_Q11B35 Cluster: Aldo/keto reductase; n=1; Mesorhizobium
sp. BNC1|Rep: Aldo/keto reductase - Mesorhizobium sp.
(strain BNC1)
Length = 253
Score = 44.0 bits (99), Expect = 0.006
Identities = 20/51 (39%), Positives = 33/51 (64%)
Frame = +3
Query: 528 RHVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGLEKPSALQIE 680
RH + WR +I A++ GLT+ IG+SN++ E I+ ++D+ E P Q+E
Sbjct: 94 RHGAGEELWRALIRAREDGLTRDIGVSNYSIELIEELVDATGEIPVVNQVE 144
Score = 37.1 bits (82), Expect = 0.70
Identities = 20/63 (31%), Positives = 33/63 (52%)
Frame = +2
Query: 170 IPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQVGRALXQEI 349
+P++ LGTW Q+T++T + V A + GY +DT+ YG + +G A+
Sbjct: 1 MPILGLGTW----------QLTHETARTVRAAFDLGYRMVDTSGDYGTQSAIGEAIRASG 50
Query: 350 LRR 358
L R
Sbjct: 51 LDR 53
>UniRef50_A4FEB9 Cluster: 2,5-diketo-D-gluconic acid reductase; n=1;
Saccharopolyspora erythraea NRRL 2338|Rep:
2,5-diketo-D-gluconic acid reductase - Saccharopolyspora
erythraea (strain NRRL 23338)
Length = 159
Score = 44.0 bits (99), Expect = 0.006
Identities = 34/75 (45%), Positives = 39/75 (52%), Gaps = 1/75 (1%)
Frame = +2
Query: 137 VPTLQLSSGGNIPVVALGTWLGHRPKGKVVQVTND-TEQAVIYALEAGYTHIDTAYKYGI 313
VPT+ L++G +P + G V QV D T AV ALEAGY IDTA YG
Sbjct: 4 VPTVTLNNGVEMPQLGYG----------VFQVPEDETAAAVGAALEAGYRSIDTAAAYGN 53
Query: 314 EDQVGRALXQEILRR 358
E VGRAL L R
Sbjct: 54 EAAVGRALAGSGLAR 68
>UniRef50_Q9ZUJ6 Cluster: T2K10.1 protein; n=16; core
eudicotyledons|Rep: T2K10.1 protein - Arabidopsis
thaliana (Mouse-ear cress)
Length = 176
Score = 44.0 bits (99), Expect = 0.006
Identities = 29/95 (30%), Positives = 48/95 (50%), Gaps = 7/95 (7%)
Frame = +3
Query: 366 RESIFITTKLWNSYHEREQVIPALRKSLXKSQLG------IRRPVFDSLA-HSYV*ERYL 524
R F+TTKLW + V+PA+++SL +L I PV + + +
Sbjct: 82 RSEFFVTTKLWCADAHGGLVVPAIKRSLKNLKLDYLDLYIIHWPVSSKPGKYKFPIDEDD 141
Query: 525 ARHVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQI 629
+DF W M + ++LGL K IG+SNF+ +++
Sbjct: 142 FMPMDFEVVWSEMEECQRLGLAKCIGVSNFSCKKL 176
Score = 40.7 bits (91), Expect = 0.056
Identities = 25/75 (33%), Positives = 41/75 (54%), Gaps = 4/75 (5%)
Frame = +2
Query: 137 VPTLQLSSGGN----IPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYK 304
VPTL + SG + +PV+ GT P+ +++ T VI A++ GY H DT+ +
Sbjct: 6 VPTLAIRSGPSGHHSMPVLGFGTAASPLPEPTMLKET------VIEAIKLGYRHFDTSPR 59
Query: 305 YGIEDQVGRALXQEI 349
Y E+ +G AL + +
Sbjct: 60 YQTEEPIGEALAEAV 74
Score = 36.3 bits (80), Expect = 1.2
Identities = 12/19 (63%), Positives = 17/19 (89%)
Frame = +1
Query: 448 LXNLNLEYVDLYLIHWPIA 504
L NL L+Y+DLY+IHWP++
Sbjct: 109 LKNLKLDYLDLYIIHWPVS 127
>UniRef50_Q75E75 Cluster: ABL209Cp; n=1; Eremothecium gossypii|Rep:
ABL209Cp - Ashbya gossypii (Yeast) (Eremothecium
gossypii)
Length = 310
Score = 44.0 bits (99), Expect = 0.006
Identities = 36/115 (31%), Positives = 59/115 (51%), Gaps = 3/115 (2%)
Frame = +3
Query: 345 KFSEGLKRESIFITTKLWNSYHEREQVIPALRKSLXKS-QLGIRRPVFDSLAHSYV*ERY 521
K + G +RE ++ TTK+ H E +L KSL + LG V L H+ + +R
Sbjct: 72 KHAPGRRREDVYFTTKINTQNHGYEATKKSLEKSLHAAGPLGYIDLV---LVHAPMSDR- 127
Query: 522 LARHVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIID-SGLE-KPSALQIE 680
R L TW+ + +A G +SIG+SN+ Q+ + ++ GL+ +P Q+E
Sbjct: 128 -TRR---LGTWQALEEAVVEGQVRSIGVSNYGQQHLSELLGWEGLKIRPVVNQVE 178
Score = 35.9 bits (79), Expect = 1.6
Identities = 26/64 (40%), Positives = 32/64 (50%), Gaps = 1/64 (1%)
Frame = +2
Query: 149 QLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIY-ALEAGYTHIDTAYKYGIEDQV 325
+LS G IP V LG V QV+ T Q ++Y ALE GY D+A Y ED V
Sbjct: 14 RLSDGTQIPSVGLG----------VYQVSEQTVQDLVYEALEVGYRLFDSAQAYHNEDGV 63
Query: 326 GRAL 337
R +
Sbjct: 64 ARGI 67
>UniRef50_A2QB88 Cluster: Contig An01c0460, complete genome.
precursor; n=1; Aspergillus niger|Rep: Contig An01c0460,
complete genome. precursor - Aspergillus niger
Length = 351
Score = 44.0 bits (99), Expect = 0.006
Identities = 39/127 (30%), Positives = 58/127 (45%), Gaps = 20/127 (15%)
Frame = +3
Query: 360 LKRESIFITTKLWNSYHEREQVIPALRKSLXKSQL--GIRRPVFD----SLAHSYV*--E 515
+ RE I +TTKL ++H V AL SL + QL G+ ++ S+ H+Y +
Sbjct: 99 IPREEIIVTTKLAQTWHRVSDVERALDLSLERLQLNYGLSMHLYSASSYSVPHAYSPGPD 158
Query: 516 RYLARHV------------DFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGLEK 659
RH D+ TW M G K IG+SNFN +++R++ S
Sbjct: 159 NNTIRHPNGKPIIDHELSRDYPSTWAAMESLVDKGKLKMIGVSNFNILKLERLLGSARIP 218
Query: 660 PSALQIE 680
P+ QIE
Sbjct: 219 PAVNQIE 225
Score = 41.5 bits (93), Expect = 0.032
Identities = 25/62 (40%), Positives = 33/62 (53%)
Frame = +2
Query: 173 PVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQVGRALXQEIL 352
P V LGT+ G V ++AV+ AL GY HIDTA YG E +VG A+ + +
Sbjct: 47 PAVGLGTFQGDAGNRGV-------KEAVLQALRCGYRHIDTATAYGNEIEVGEAIKESRI 99
Query: 353 RR 358
R
Sbjct: 100 PR 101
>UniRef50_A4IJ00 Cluster: LOC548351 protein; n=1; Xenopus
tropicalis|Rep: LOC548351 protein - Xenopus tropicalis
(Western clawed frog) (Silurana tropicalis)
Length = 248
Score = 43.6 bits (98), Expect = 0.008
Identities = 28/75 (37%), Positives = 43/75 (57%), Gaps = 1/75 (1%)
Frame = +2
Query: 137 VPTLQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEA-GYTHIDTAYKYGI 313
+PT+ L+SG +IP++ LG + H V A++YAL G HIDTA +YG
Sbjct: 6 IPTVPLASGKHIPLLGLG--MSH--------VGGYCHNALLYALTTCGIRHIDTAKRYGN 55
Query: 314 EDQVGRALXQEILRR 358
E VG+A+ + ++R
Sbjct: 56 EVMVGKAICESGVKR 70
Score = 30.7 bits (66), Expect(2) = 2.0
Identities = 18/45 (40%), Positives = 24/45 (53%), Gaps = 3/45 (6%)
Frame = +3
Query: 357 GLKRESIFITTKLWNSYHEREQVIPALR---KSLXKSQLGIRRPV 482
G+KRE +++TTKLW + E I A K L LGI R +
Sbjct: 67 GVKREELWLTTKLWPGDYGYENAIQACLDSCKRLGVDYLGICRSI 111
Score = 23.8 bits (49), Expect(2) = 2.0
Identities = 11/34 (32%), Positives = 19/34 (55%)
Frame = +3
Query: 579 LGLTKSIGISNFNQEQIQRIIDSGLEKPSALQIE 680
LG+ +SIG+SNF + ++ + P Q+E
Sbjct: 105 LGICRSIGVSNFLIHHLDQLKEDCNMVPHLNQVE 138
>UniRef50_Q5B5R6 Cluster: Putative uncharacterized protein; n=1;
Emericella nidulans|Rep: Putative uncharacterized
protein - Emericella nidulans (Aspergillus nidulans)
Length = 682
Score = 43.6 bits (98), Expect = 0.008
Identities = 27/73 (36%), Positives = 41/73 (56%)
Frame = +2
Query: 143 TLQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQ 322
+ +L++G IP V LGT +P G V + AV AL+ GY HIDTA G+E +
Sbjct: 413 SFRLNTGALIPAVGLGTRRAQKP-GLVYR-------AVRSALKTGYRHIDTAMSSGVEHE 464
Query: 323 VGRALXQEILRRT 361
+G+A+ + R+
Sbjct: 465 IGQAVKDSGVSRS 477
>UniRef50_Q0CLQ2 Cluster: Putative uncharacterized protein; n=1;
Aspergillus terreus NIH2624|Rep: Putative
uncharacterized protein - Aspergillus terreus (strain
NIH 2624)
Length = 301
Score = 43.6 bits (98), Expect = 0.008
Identities = 27/62 (43%), Positives = 36/62 (58%)
Frame = +2
Query: 143 TLQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQ 322
+ +LSSG ++P V LGTWL +P ++ E AV AL GY HID A Y E++
Sbjct: 6 SFKLSSGYDMPAVGLGTWLS-KP--------HEVENAVETALRLGYRHIDAAACYLNENE 56
Query: 323 VG 328
VG
Sbjct: 57 VG 58
Score = 38.7 bits (86), Expect = 0.23
Identities = 16/35 (45%), Positives = 24/35 (68%)
Frame = +3
Query: 357 GLKRESIFITTKLWNSYHEREQVIPALRKSLXKSQ 461
G+ R+ IFIT+KLWN++H + V A+ K+L Q
Sbjct: 65 GVPRDQIFITSKLWNTHHHPDHVEEAVNKTLKDLQ 99
Score = 38.7 bits (86), Expect = 0.23
Identities = 17/56 (30%), Positives = 30/56 (53%)
Frame = +3
Query: 513 ERYLARHVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGLEKPSALQIE 680
+R+ ++ DTW + G +SIG+SNF E+I+ ++ + P+ QIE
Sbjct: 149 KRFRLANIPIADTWAALEKLVDAGKVRSIGVSNFTIEKIEELLKTARIPPAVNQIE 204
>UniRef50_Q8Y463 Cluster: Lmo2592 protein; n=40; Bacteria|Rep:
Lmo2592 protein - Listeria monocytogenes
Length = 283
Score = 43.2 bits (97), Expect = 0.011
Identities = 25/67 (37%), Positives = 40/67 (59%), Gaps = 2/67 (2%)
Frame = +2
Query: 143 TLQLSSGGNIPVVALGTWLGHRPKGKVVQVTN--DTEQAVIYALEAGYTHIDTAYKYGIE 316
T++L++G +P++ GT+ Q+T+ + E AV A++AGY HIDTA Y E
Sbjct: 3 TVKLNNGVEVPILGFGTY----------QITDAAEAEHAVKDAIKAGYRHIDTAQSYMNE 52
Query: 317 DQVGRAL 337
+ VGR +
Sbjct: 53 EAVGRGI 59
Score = 33.9 bits (74), Expect = 6.5
Identities = 31/113 (27%), Positives = 52/113 (46%), Gaps = 3/113 (2%)
Frame = +3
Query: 351 SEGLKRESIFITTKLWNSYHEREQVIPALRKSLXKSQLGIRRPVFDSLAHSYV*ERYLAR 530
+ G+ R+ +FITTK+W + V+ + +SL +LG+ YV L
Sbjct: 61 ASGVDRKELFITTKIWVENVSYKGVMSSFDRSL--KRLGL----------DYV--DLLLI 106
Query: 531 HVDFLD---TWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGLEKPSALQIE 680
H F D W M + + G ++IG+SNF+ +++ + P QIE
Sbjct: 107 HQPFNDVYGAWIAMEELQASGKIRAIGVSNFSPDRVIDLAAFNEVTPQVNQIE 159
>UniRef50_A6LZ55 Cluster: 2,5-didehydrogluconate reductase; n=1;
Clostridium beijerinckii NCIMB 8052|Rep:
2,5-didehydrogluconate reductase - Clostridium
beijerinckii NCIMB 8052
Length = 289
Score = 43.2 bits (97), Expect = 0.011
Identities = 29/107 (27%), Positives = 46/107 (42%)
Frame = +3
Query: 360 LKRESIFITTKLWNSYHEREQVIPALRKSLXKSQLGIRRPVFDSLAHSYV*ERYLARHVD 539
+ RE FIT+K+WN+ H E A ++ K + A SY
Sbjct: 68 IPREEFFITSKVWNTDHGYEATKKAFEQTCKKLNVEYLDMYLIHFASSY----------- 116
Query: 540 FLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGLEKPSALQIE 680
+L+TW M + G K IG++NF + ++ ++ P QIE
Sbjct: 117 YLETWHAMEELYLQGKIKVIGVANFQIQHLEELMKHSRITPMINQIE 163
Score = 33.9 bits (74), Expect = 6.5
Identities = 26/77 (33%), Positives = 39/77 (50%)
Frame = +2
Query: 128 DLIVPTLQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKY 307
+LI ++ +G IP V G + + KG+ D E AV A++ GY H DTA Y
Sbjct: 2 NLINKEIKAVNGIKIPQVGFGVYKLN--KGE------DFETAVGEAIKIGYRHFDTAKIY 53
Query: 308 GIEDQVGRALXQEILRR 358
G E +G A+ + + R
Sbjct: 54 GNEKDLGLAIEKSQIPR 70
>UniRef50_A5AD50 Cluster: Putative uncharacterized protein; n=3;
Magnoliophyta|Rep: Putative uncharacterized protein -
Vitis vinifera (Grape)
Length = 304
Score = 43.2 bits (97), Expect = 0.011
Identities = 26/63 (41%), Positives = 34/63 (53%)
Frame = +2
Query: 149 QLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQVG 328
QL++G +P V LGTW G V QAV A++ GY HID A YG E+++G
Sbjct: 9 QLNTGAKMPSVGLGTW--QSDPGLV-------GQAVAIAIKVGYRHIDCAQVYGNEEEIG 59
Query: 329 RAL 337
L
Sbjct: 60 IVL 62
>UniRef50_Q1DLF1 Cluster: Putative uncharacterized protein; n=1;
Coccidioides immitis|Rep: Putative uncharacterized
protein - Coccidioides immitis
Length = 324
Score = 43.2 bits (97), Expect = 0.011
Identities = 35/120 (29%), Positives = 55/120 (45%), Gaps = 10/120 (8%)
Frame = +3
Query: 351 SEGLKRESIFITTKLWNSYHEREQVIPALRKSLXKSQLGIRRPVFDSLAHSY-------- 506
+ G+ RE +F+ TKL N +H E V + SL LG P + +Y
Sbjct: 72 ASGVPREDVFVVTKLHNCFHAPEDVEVGMNMSLKNLGLGY-VPYAYTKGENYSTVRKPDG 130
Query: 507 --V*ERYLARHVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGLEKPSALQIE 680
V + L+R D TW+ M + G K IG+SNF+ +++R++ P Q+E
Sbjct: 131 KPVVDIELSRAFD--TTWKAMENLVDQGKAKLIGVSNFSTPKLKRLLSVCRIFPVVNQVE 188
>UniRef50_Q838E0 Cluster: Oxidoreductase, aldo/keto reductase
family; n=24; Bacilli|Rep: Oxidoreductase, aldo/keto
reductase family - Enterococcus faecalis (Streptococcus
faecalis)
Length = 279
Score = 42.7 bits (96), Expect = 0.014
Identities = 28/108 (25%), Positives = 53/108 (49%)
Frame = +3
Query: 357 GLKRESIFITTKLWNSYHEREQVIPALRKSLXKSQLGIRRPVFDSLAHSYV*ERYLARHV 536
GL RE +F+T+K+WN++ ++ I A SL +LG+ D L + + +
Sbjct: 71 GLNREDLFVTSKVWNAHISYDETIQAFNDSL--ERLGL-----DYLDLYLI---HWPGNN 120
Query: 537 DFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGLEKPSALQIE 680
+ ++W+ + G K+IG+SNF ++ ++ P Q+E
Sbjct: 121 SYKESWQALETLYAEGKVKAIGVSNFQVHHLEDLLSYAKVVPVINQVE 168
>UniRef50_Q7PM68 Cluster: ENSANGP00000014386; n=1; Anopheles gambiae
str. PEST|Rep: ENSANGP00000014386 - Anopheles gambiae
str. PEST
Length = 310
Score = 42.7 bits (96), Expect = 0.014
Identities = 33/117 (28%), Positives = 52/117 (44%), Gaps = 10/117 (8%)
Frame = +3
Query: 360 LKRESIFITTKLWNSYHEREQVIPALRKSLXKSQLGIRRPVFDSLAHSYV*ERYLARHVD 539
L R+ FI +KL SYH ++ V R +L + + + E+ AR+
Sbjct: 73 LTRDDFFIISKLSGSYHRQDLVEKCCRMTLDRLGMDYVDLYLMHTPVALQSEKKCARNGT 132
Query: 540 FL----------DTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGLEKPSALQIE 680
L + W G+ + GL +SIG+SNFN+ QI ++ P+ QIE
Sbjct: 133 KLNAIDDSIAPTEAWIGLEQCYQEGLCRSIGVSNFNEHQINALLSDASIVPAVNQIE 189
>UniRef50_Q76L36 Cluster: Conjugated polyketone reductase C2; n=1;
Candida parapsilosis|Rep: Conjugated polyketone
reductase C2 - Candida parapsilosis (Yeast)
Length = 307
Score = 42.7 bits (96), Expect = 0.014
Identities = 23/73 (31%), Positives = 38/73 (52%)
Frame = +2
Query: 119 TSADLIVPTLQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTA 298
T ++L+ T + SG I + ALGT + + V+ + ++ L+ G+ HIDTA
Sbjct: 2 TQSNLLPKTFRTKSGKEISI-ALGTGTKWKQAQTINDVSTELVDNILLGLKLGFRHIDTA 60
Query: 299 YKYGIEDQVGRAL 337
Y + +VG AL
Sbjct: 61 EAYNTQKEVGEAL 73
>UniRef50_UPI00006CD296 Cluster: oxidoreductase, aldo/keto reductase
family protein; n=1; Tetrahymena thermophila SB210|Rep:
oxidoreductase, aldo/keto reductase family protein -
Tetrahymena thermophila SB210
Length = 295
Score = 42.3 bits (95), Expect = 0.018
Identities = 32/112 (28%), Positives = 52/112 (46%), Gaps = 1/112 (0%)
Frame = +3
Query: 348 FSEG-LKRESIFITTKLWNSYHEREQVIPALRKSLXKSQLGIRRPVFDSLAHSYV*ERYL 524
+ EG KRE +F+ TKL+++ + +V +R+SL Q A S +++
Sbjct: 67 YKEGKYKREDLFLVTKLFSN--KNTKVEDQVRQSLQNLQTNYIDLYLLHYASSPPTDQFE 124
Query: 525 ARHVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGLEKPSALQIE 680
H W + + GL ++IGISNFN + + + KP QIE
Sbjct: 125 LTHKPVFQVWAEFEELVQKGLIRNIGISNFNVQMLLDLYSYCKIKPVVNQIE 176
Score = 40.7 bits (91), Expect = 0.056
Identities = 29/71 (40%), Positives = 38/71 (53%)
Frame = +2
Query: 143 TLQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQ 322
T +L +G +PV LGT+ KVV + + AL+ GY HIDTA Y E Q
Sbjct: 7 TTELCNGSKLPVFGLGTY-------KVVS-KEEMVTFLRTALDLGYRHIDTAIMYENEKQ 58
Query: 323 VGRALXQEILR 355
+G AL QEI +
Sbjct: 59 IGDAL-QEIYK 68
>UniRef50_Q929C8 Cluster: Lin2349 protein; n=12; Listeria|Rep:
Lin2349 protein - Listeria innocua
Length = 294
Score = 42.3 bits (95), Expect = 0.018
Identities = 31/105 (29%), Positives = 50/105 (47%)
Frame = +3
Query: 366 RESIFITTKLWNSYHEREQVIPALRKSLXKSQLGIRRPVFDSLAHSYV*ERYLARHVDFL 545
RE +FI++K+WN ++ + A ++L +L L H V +Y
Sbjct: 71 REELFISSKVWNGDLGYDETLFAFERTLRNLKLDYLDLY---LIHWPVAGKYR------- 120
Query: 546 DTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGLEKPSALQIE 680
D+WR M L KSIG++NF Q + ++ + EKP Q+E
Sbjct: 121 DSWRAMERLHDEKLIKSIGVANFKQHHLSDLLVAANEKPVLNQVE 165
Score = 38.3 bits (85), Expect = 0.30
Identities = 14/19 (73%), Positives = 17/19 (89%)
Frame = +1
Query: 448 LXNLNLEYVDLYLIHWPIA 504
L NL L+Y+DLYLIHWP+A
Sbjct: 98 LRNLKLDYLDLYLIHWPVA 116
>UniRef50_Q5FLI5 Cluster: Aldehyde reductase; n=2; Bacteria|Rep:
Aldehyde reductase - Lactobacillus acidophilus
Length = 278
Score = 42.3 bits (95), Expect = 0.018
Identities = 32/107 (29%), Positives = 52/107 (48%), Gaps = 2/107 (1%)
Frame = +3
Query: 366 RESIFITTKLWNSYHEREQVIPALRKSLXKSQLGIRRPVFDSLAHSYV*ERYLAR--HVD 539
RE IFIT+K+W + + + A S+ K QL Y+ + YL + D
Sbjct: 67 REDIFITSKIWVDDYGYDNTLKAFDDSMKKLQL------------DYI-DLYLIHKPYND 113
Query: 540 FLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGLEKPSALQIE 680
+ TWR + + G ++IG+S+F E++ +I KP+ QIE
Sbjct: 114 YYGTWRALERLYQEGRIRAIGVSSFWNERLADLITFNDVKPAVNQIE 160
>UniRef50_Q1Q8W8 Cluster: Aldo/keto reductase; n=1; Psychrobacter
cryohalolentis K5|Rep: Aldo/keto reductase -
Psychrobacter cryohalolentis (strain K5)
Length = 282
Score = 42.3 bits (95), Expect = 0.018
Identities = 26/71 (36%), Positives = 36/71 (50%)
Frame = +2
Query: 146 LQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQV 325
++ + NIPV+ LGTW + G+ D V L GY HIDTA YG E +V
Sbjct: 8 IRTAGQANIPVLGLGTW---QSTGQ------DCIDVVSQGLRMGYEHIDTAQAYGNEVEV 58
Query: 326 GRALXQEILRR 358
G+ + Q + R
Sbjct: 59 GKGIKQSGVAR 69
Score = 35.1 bits (77), Expect = 2.8
Identities = 26/89 (29%), Positives = 47/89 (52%), Gaps = 2/89 (2%)
Frame = +3
Query: 357 GLKRESIFITTKLW--NSYHEREQVIPALRKSLXKSQLGIRRPVFDSLAHSYV*ERYLAR 530
G+ R+ F+TTK++ + E E+++ A ++SL + D L + +R
Sbjct: 66 GVARDKFFLTTKIFPDDMKFEPEKLVAAAKRSLEN----LDTDYVDLLLLHWPDDR---- 117
Query: 531 HVDFLDTWRGMIDAKKLGLTKSIGISNFN 617
V +T + + +K GLT++IG+SNFN
Sbjct: 118 -VPLSETIPALCELQKQGLTRNIGVSNFN 145
>UniRef50_Q4WI64 Cluster: Aldehyde reductase, putative; n=22;
Pezizomycotina|Rep: Aldehyde reductase, putative -
Aspergillus fumigatus (Sartorya fumigata)
Length = 295
Score = 42.3 bits (95), Expect = 0.018
Identities = 31/102 (30%), Positives = 54/102 (52%), Gaps = 3/102 (2%)
Frame = +3
Query: 357 GLKRESIFITTKLWNSYHEREQVIPALRKSLXKSQLGIRRPVFDSLAHSYV*ERYLARHV 536
G+ R IF TTK+ S E+ A+ +S+ + LG + L H+ Y +
Sbjct: 81 GIDRSKIFFTTKVPASSMSYEKAKEAIEQSVAATDLGYIDLI---LLHA----PYGGKE- 132
Query: 537 DFLDTWRGMIDAKKLGLTKSIGISNF---NQEQIQRIIDSGL 653
L WR +++A+K G +SIG+SN+ + E+++ I+SG+
Sbjct: 133 GRLGAWRALVEAQKAGHVRSIGVSNYGIHHLEELEEYINSGV 174
Score = 33.5 bits (73), Expect = 8.6
Identities = 16/40 (40%), Positives = 24/40 (60%)
Frame = +2
Query: 242 TEQAVIYALEAGYTHIDTAYKYGIEDQVGRALXQEILRRT 361
TE+A + ALE GY HID+A Y E + A+ + + R+
Sbjct: 46 TEKATLKALETGYRHIDSAKYYANEKECAVAMKKSGIDRS 85
>UniRef50_A6SI80 Cluster: Putative uncharacterized protein; n=1;
Botryotinia fuckeliana B05.10|Rep: Putative
uncharacterized protein - Botryotinia fuckeliana B05.10
Length = 253
Score = 42.3 bits (95), Expect = 0.018
Identities = 39/123 (31%), Positives = 57/123 (46%), Gaps = 21/123 (17%)
Frame = +3
Query: 375 IFITTKLWNSYHEREQVIPALRKSLXKSQLGIRRPVFD-SLAHSYV*ERYLARHVDF--- 542
+FI +KLWNS+H+ ++V P RK L + GI FD + H V RY+ V +
Sbjct: 50 LFIVSKLWNSFHDGDRVGPITRKQL--ADWGI--DYFDLFIVHFPVALRYVDPAVRYPPG 105
Query: 543 -----------------LDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGLEKPSAL 671
+TW+ M GL KSIG+SNF + ++ +P+ L
Sbjct: 106 WQYSDKEGDVQQSKASIQETWQAMEKLVDEGLAKSIGVSNFQGALLIDLLRYARIRPATL 165
Query: 672 QIE 680
QIE
Sbjct: 166 QIE 168
>UniRef50_A6RMS0 Cluster: Putative uncharacterized protein; n=1;
Botryotinia fuckeliana B05.10|Rep: Putative
uncharacterized protein - Botryotinia fuckeliana B05.10
Length = 286
Score = 42.3 bits (95), Expect = 0.018
Identities = 24/72 (33%), Positives = 38/72 (52%)
Frame = +2
Query: 143 TLQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQ 322
+ +L +G +P + LGT+ G KV + V A++AGY HID A YG E+
Sbjct: 7 SFRLVNGSTLPAIGLGTFQGDDGNEKVKNI-------VKAAIQAGYRHIDGAAAYGNEEA 59
Query: 323 VGRALXQEILRR 358
+G A+ + + R
Sbjct: 60 IGDAIKESGISR 71
Score = 36.7 bits (81), Expect = 0.92
Identities = 16/47 (34%), Positives = 28/47 (59%)
Frame = +3
Query: 540 FLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGLEKPSALQIE 680
+ +TW+ M G K+IG+SNFN + +RI++ +P+ Q+E
Sbjct: 119 YTETWQAMEKLVDSGKAKAIGLSNFNILKTKRILEIARIRPAVNQVE 165
>UniRef50_P82125 Cluster: 1,5-anhydro-D-fructose reductase; n=1; Sus
scrofa|Rep: 1,5-anhydro-D-fructose reductase - Sus
scrofa (Pig)
Length = 206
Score = 42.3 bits (95), Expect = 0.018
Identities = 25/60 (41%), Positives = 34/60 (56%)
Frame = +2
Query: 170 IPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQVGRALXQEI 349
IPV+ LGTW P G+V + AV A++ GY H D+AY Y ED+VG + +I
Sbjct: 2 IPVLGLGTWQA-APGGEVTE-------AVKVAIDTGYRHPDSAYLYHNEDEVGVGIQAKI 53
>UniRef50_A7RRF6 Cluster: Predicted protein; n=2; Nematostella
vectensis|Rep: Predicted protein - Nematostella
vectensis
Length = 275
Score = 41.9 bits (94), Expect = 0.024
Identities = 22/46 (47%), Positives = 30/46 (65%)
Frame = +2
Query: 242 TEQAVIYALEAGYTHIDTAYKYGIEDQVGRALXQEILRRT*KRIYL 379
T+QAV++ALE GY IDTA Y E +VG AL + + R+ +YL
Sbjct: 30 TKQAVLWALENGYRMIDTAASYNNEKRVGEALRESAVPRS--EVYL 73
Score = 41.1 bits (92), Expect = 0.043
Identities = 31/105 (29%), Positives = 52/105 (49%)
Frame = +3
Query: 366 RESIFITTKLWNSYHEREQVIPALRKSLXKSQLGIRRPVFDSLAHSYV*ERYLARHVDFL 545
R +++ TK++++ H E+ + A +SL S LG+ V L H V +
Sbjct: 68 RSEVYLVTKVYHTDHGYEKTMKAYDRSL--SALGVDY-VDLYLIHFPV-------PAGVV 117
Query: 546 DTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGLEKPSALQIE 680
+W M + + GLT+SIG+SNFN ++ + + P QIE
Sbjct: 118 GSWEAMAELQGKGLTRSIGVSNFNIHHLEALQKHSVIPPVVNQIE 162
>UniRef50_UPI00015B5BD7 Cluster: PREDICTED: similar to aldo-keto
reductase; n=1; Nasonia vitripennis|Rep: PREDICTED:
similar to aldo-keto reductase - Nasonia vitripennis
Length = 310
Score = 41.5 bits (93), Expect = 0.032
Identities = 37/114 (32%), Positives = 57/114 (50%), Gaps = 7/114 (6%)
Frame = +3
Query: 360 LKRESIFITTKLWNSYHEREQVIPALRKSLXKSQLGIRRPVFDS-LAHSYV*ERYLARHV 536
LKRE IFIT+KL S + I RKS+ S + D L H R L
Sbjct: 90 LKREDIFITSKLSPSDNGDPDKI---RKSVEDSLKALDTSYLDLYLIHWPGASRILENSP 146
Query: 537 DF----LDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIID--SGLEKPSALQIE 680
D + TW +++ ++ GL +SIG+SN+ ++ +++ SG+ KP Q+E
Sbjct: 147 DNPKLRVTTWATLVELQQKGLLRSIGVSNYTVGHLEHLLEHCSGV-KPDVNQVE 199
>UniRef50_UPI0000D9A956 Cluster: PREDICTED: similar to aldo-keto
reductase family 1, member B10, partial; n=1; Macaca
mulatta|Rep: PREDICTED: similar to aldo-keto reductase
family 1, member B10, partial - Macaca mulatta
Length = 275
Score = 41.5 bits (93), Expect = 0.032
Identities = 20/46 (43%), Positives = 30/46 (65%)
Frame = +2
Query: 245 EQAVIYALEAGYTHIDTAYKYGIEDQVGRALXQEILRRT*KRIYLY 382
++AV A++AGY HID AY Y E +VG A+ ++I + KR L+
Sbjct: 49 KEAVKVAIDAGYRHIDCAYVYQNEHEVGEAIQEKIQEQAVKREDLF 94
Score = 40.7 bits (91), Expect = 0.056
Identities = 37/117 (31%), Positives = 59/117 (50%), Gaps = 8/117 (6%)
Frame = +3
Query: 354 EGLKRESIFITTK------LWNSYHEREQVIPALRKSLXKSQLGIRRPVFDSLAHSYV*E 515
+ +KRE +FI +K LW ++ ER P +RK+ K+ L SY+ +
Sbjct: 86 QAVKREDLFIVSKVHMAHWLWTTFFER----PLVRKAFEKT--------LKDLKLSYL-D 132
Query: 516 RYLARHVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDS-GLE-KPSALQIE 680
YL ++D GL K++GISNFN QI+++++ GL+ KP Q+E
Sbjct: 133 VYLIHWPQGFKAMEELVDE---GLVKALGISNFNHFQIEKLLNKPGLKYKPVTNQVE 186
>UniRef50_Q6U5V3 Cluster: Putative uncharacterized protein; n=1;
Klebsiella pneumoniae|Rep: Putative uncharacterized
protein - Klebsiella pneumoniae
Length = 279
Score = 41.5 bits (93), Expect = 0.032
Identities = 17/47 (36%), Positives = 30/47 (63%)
Frame = +3
Query: 540 FLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGLEKPSALQIE 680
+++TW I+ + GL +SIG+SNF + I+R+I+ P+ Q+E
Sbjct: 117 YVETWEASIELEASGLIRSIGVSNFTCQHIERLIEDTGVVPAVNQLE 163
Score = 36.7 bits (81), Expect = 0.92
Identities = 17/33 (51%), Positives = 21/33 (63%)
Frame = +2
Query: 239 DTEQAVIYALEAGYTHIDTAYKYGIEDQVGRAL 337
D + + AL+AG+ H DTA Y ED VGRAL
Sbjct: 28 DVDSLIRQALKAGFRHFDTAQAYFNEDGVGRAL 60
>UniRef50_A5BYJ4 Cluster: Putative uncharacterized protein; n=1;
Vitis vinifera|Rep: Putative uncharacterized protein -
Vitis vinifera (Grape)
Length = 107
Score = 41.5 bits (93), Expect = 0.032
Identities = 23/73 (31%), Positives = 40/73 (54%)
Frame = +2
Query: 137 VPTLQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIE 316
+P + L SG +P++ +GT P+ ++T+ ++ A+E GY H DTA Y E
Sbjct: 7 IPGVLLRSGXEMPLIGMGTATSPFPQPH--RLTS----ILVDAIEVGYRHFDTAAHYASE 60
Query: 317 DQVGRALXQEILR 355
+ +GRA+ + R
Sbjct: 61 EPLGRAVAXAVAR 73
>UniRef50_Q4WUF7 Cluster: Aldo-keto reductase, putative; n=3;
Pezizomycotina|Rep: Aldo-keto reductase, putative -
Aspergillus fumigatus (Sartorya fumigata)
Length = 283
Score = 41.5 bits (93), Expect = 0.032
Identities = 27/72 (37%), Positives = 37/72 (51%)
Frame = +2
Query: 122 SADLIVPTLQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAY 301
S+ L + L ++ + LG + P G+ VQ + + ALEAGY HIDTA
Sbjct: 2 SSKLTITDLLPLPNSDVKIPRLGFGVYRSPTGQCVQSS-------LRALEAGYRHIDTAQ 54
Query: 302 KYGIEDQVGRAL 337
YG E +VG AL
Sbjct: 55 FYGNEKEVGEAL 66
>UniRef50_Q4WF80 Cluster: Glycerol dehydrogenase (GCY1), putative;
n=1; Aspergillus fumigatus|Rep: Glycerol dehydrogenase
(GCY1), putative - Aspergillus fumigatus (Sartorya
fumigata)
Length = 274
Score = 41.5 bits (93), Expect = 0.032
Identities = 24/58 (41%), Positives = 35/58 (60%), Gaps = 1/58 (1%)
Frame = +2
Query: 131 LIVPT-LQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAY 301
+ +PT +L++G IP + LGTW G+V QAV +AL+ GY+HIDTA+
Sbjct: 1 MALPTHFKLNTGAQIPAIGLGTWRSE--PGQV-------RQAVSFALKNGYSHIDTAF 49
>UniRef50_A6VNW9 Cluster: Aldo/keto reductase precursor; n=1;
Actinobacillus succinogenes 130Z|Rep: Aldo/keto
reductase precursor - Actinobacillus succinogenes 130Z
Length = 315
Score = 41.1 bits (92), Expect = 0.043
Identities = 24/65 (36%), Positives = 36/65 (55%)
Frame = +2
Query: 143 TLQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQ 322
T++L++G +P++ +G W TE++V AL+AGY IDTA Y E
Sbjct: 44 TVKLNNGIEMPIIGIGVW---------TLTPEQTEKSVGEALKAGYRLIDTARMYRNEQA 94
Query: 323 VGRAL 337
VGRA+
Sbjct: 95 VGRAV 99
Score = 35.1 bits (77), Expect = 2.8
Identities = 30/110 (27%), Positives = 53/110 (48%), Gaps = 2/110 (1%)
Frame = +3
Query: 357 GLKRESIFITTKLWNSYHEREQVIPALRKSLXKSQLGIRRPVFDSLAHSYV*ERYLARHV 536
G+ RE IFITTK++ S ++ + R + D+ Y+ + L +
Sbjct: 103 GIPREEIFITTKIYGSGDYANA----------EAAINERLRLLDT---DYI-DLLLLHYP 148
Query: 537 DFLDT--WRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGLEKPSALQIE 680
D DT W+ M K G ++IG+SN++++ RI+ + P+ +Q E
Sbjct: 149 DQNDTKAWKVMEQFVKAGKIRAIGLSNYHRKTFNRIMQAATITPAVVQNE 198
>UniRef50_A0L1A2 Cluster: Aldo/keto reductase; n=8;
Gammaproteobacteria|Rep: Aldo/keto reductase -
Shewanella sp. (strain ANA-3)
Length = 280
Score = 41.1 bits (92), Expect = 0.043
Identities = 27/97 (27%), Positives = 46/97 (47%)
Frame = +3
Query: 351 SEGLKRESIFITTKLWNSYHEREQVIPALRKSLXKSQLGIRRPVFDSLAHSYV*ERYLAR 530
+ G+ RE +FITTK+W +E+ S+ S ++ D L +
Sbjct: 65 TSGIPREELFITTKVWTENLTKER----FETSVIDSLTALQTKYLDLLLIHWPLNSDEPS 120
Query: 531 HVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRII 641
V++L + ++D GLT+ IG+SNF Q+ + I
Sbjct: 121 MVEYLSELKAVLDK---GLTRRIGVSNFTNAQLAQAI 154
Score = 35.1 bits (77), Expect = 2.8
Identities = 23/61 (37%), Positives = 31/61 (50%)
Frame = +2
Query: 236 NDTEQAVIYALEAGYTHIDTAYKYGIEDQVGRALXQEILRRT*KRIYLYNYQALEFLPRE 415
N AV+ ALE G HIDTA YG E VG A+ + R + +++ E L +E
Sbjct: 30 NAAFDAVLMALEEGSRHIDTAQIYGNEQAVGDAINTSGIPR--EELFITTKVWTENLTKE 87
Query: 416 R 418
R
Sbjct: 88 R 88
>UniRef50_Q5KKZ8 Cluster: Aldo-keto reductase, putative; n=2;
Filobasidiella neoformans|Rep: Aldo-keto reductase,
putative - Cryptococcus neoformans (Filobasidiella
neoformans)
Length = 293
Score = 41.1 bits (92), Expect = 0.043
Identities = 23/65 (35%), Positives = 35/65 (53%)
Frame = +2
Query: 143 TLQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQ 322
T++L+SG IP + G + + + E AV A++ GY H+DTA Y E+
Sbjct: 8 TIKLASGNLIPRLGFGVYQAR---------SKECEDAVKKAIDTGYRHVDTAQAYHNEEN 58
Query: 323 VGRAL 337
VGRA+
Sbjct: 59 VGRAI 63
Score = 36.7 bits (81), Expect = 0.92
Identities = 28/100 (28%), Positives = 48/100 (48%), Gaps = 4/100 (4%)
Frame = +3
Query: 351 SEGLKRESIFITTKLWNSY--HEREQVIPALRKSLXK-SQLGIRRPVFD-SLAHSYV*ER 518
+ G+ R S+F+T+K S+ + +V+ +RKSL K + G +P D L H+
Sbjct: 65 NSGVPRPSVFLTSKYMPSHTVYSPTEVLDVVRKSLKKVDRCGDDKPYIDLMLIHAP---- 120
Query: 519 YLARHVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRI 638
+ W + A+K G K IG+SNF ++ +
Sbjct: 121 -WGGEEGRKNNWEALTIAQKEGWVKDIGVSNFGIHHLKAL 159
>UniRef50_Q5HR31 Cluster: Oxidoreductase, aldo/keto reductase
family; n=3; Staphylococcus|Rep: Oxidoreductase,
aldo/keto reductase family - Staphylococcus epidermidis
(strain ATCC 35984 / RP62A)
Length = 279
Score = 40.7 bits (91), Expect = 0.056
Identities = 28/107 (26%), Positives = 51/107 (47%)
Frame = +3
Query: 360 LKRESIFITTKLWNSYHEREQVIPALRKSLXKSQLGIRRPVFDSLAHSYV*ERYLARHVD 539
++R+ +FIT+KLWN Y +Q I KSL LG+ D + E
Sbjct: 65 VERDELFITSKLWNDYQGYDQTIEYFNKSL--DNLGL--DYLDLFLIHWPCENDQL---- 116
Query: 540 FLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGLEKPSALQIE 680
++++++ + + G K+IG+ NF +++++ P QIE
Sbjct: 117 YIESYKALEHLYEEGKIKAIGVCNFKIHHLEKLMKETKITPQVNQIE 163
Score = 36.3 bits (80), Expect = 1.2
Identities = 25/69 (36%), Positives = 34/69 (49%)
Frame = +2
Query: 152 LSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQVGR 331
L++G +P V LG + K+ E+ V AL+AGY DTAY YG E +G
Sbjct: 8 LNNGYPMPAVGLGVY-------KIAD--EQMEEVVRTALDAGYRAFDTAYFYGNEKALGS 58
Query: 332 ALXQEILRR 358
AL + R
Sbjct: 59 ALKHSNVER 67
Score = 35.5 bits (78), Expect = 2.1
Identities = 16/26 (61%), Positives = 19/26 (73%)
Frame = +1
Query: 448 LXNLNLEYVDLYLIHWPIAMFENDTL 525
L NL L+Y+DL+LIHWP END L
Sbjct: 94 LDNLGLDYLDLFLIHWPC---ENDQL 116
>UniRef50_A7PNI3 Cluster: Chromosome chr1 scaffold_22, whole genome
shotgun sequence; n=2; Vitis vinifera|Rep: Chromosome
chr1 scaffold_22, whole genome shotgun sequence - Vitis
vinifera (Grape)
Length = 360
Score = 40.7 bits (91), Expect = 0.056
Identities = 33/122 (27%), Positives = 59/122 (48%), Gaps = 11/122 (9%)
Frame = +3
Query: 348 FSEGLKRESIFITTKLW---NSYHEREQVIPALRKSLXKSQLGI---RRPVFDSLAHSYV 509
F+ LKRE +F+T+KL+ NS ++ E + K+L + L + P + +
Sbjct: 70 FNGSLKREDVFLTSKLYCTMNSLNKIENSVRVSLKNLGVTYLDLYLMHWPDITAFGDATD 129
Query: 510 *ERYLAR-HVDFLD----TWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGLEKPSALQ 674
H FL+ W+ M +LGL ++IG+SNF +QI+ ++ P+ Q
Sbjct: 130 PPSNSGNDHRQFLNRLKKAWKAMEGLIELGLVRAIGVSNFGVQQIKELLKFAKIVPAVNQ 189
Query: 675 IE 680
++
Sbjct: 190 VK 191
Score = 36.3 bits (80), Expect = 1.2
Identities = 25/64 (39%), Positives = 33/64 (51%)
Frame = +2
Query: 152 LSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQVGR 331
L++ IP + LGTW G + V +AV AL GY ID A+ YG E +VG
Sbjct: 14 LNTKAKIPAIGLGTW----QSGGDLCV-----EAVKRALSEGYRQIDCAHLYGNEVEVGE 64
Query: 332 ALXQ 343
AL +
Sbjct: 65 ALAE 68
>UniRef50_O13848 Cluster: NADH/NADPH dependent indole-3-acetaldehyde
reductase AKR3C2; n=1; Schizosaccharomyces pombe|Rep:
NADH/NADPH dependent indole-3-acetaldehyde reductase
AKR3C2 - Schizosaccharomyces pombe (Fission yeast)
Length = 284
Score = 40.7 bits (91), Expect = 0.056
Identities = 24/64 (37%), Positives = 37/64 (57%)
Frame = +2
Query: 170 IPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQVGRALXQEI 349
+P +GT L + KG++ + D+ V AL AG+ HID A YG E++VG AL +
Sbjct: 12 VPAYGVGTALFKKEKGEINRTIVDS---VKNALAAGFIHIDCAEVYGNEEEVGVALKEAN 68
Query: 350 LRRT 361
+ R+
Sbjct: 69 VPRS 72
Score = 38.7 bits (86), Expect = 0.23
Identities = 31/106 (29%), Positives = 50/106 (47%), Gaps = 1/106 (0%)
Frame = +3
Query: 366 RESIFITTKLWNSYHEREQVIPALRKSLXKSQLGIRRPVFDS-LAHSYV*ERYLARHVDF 542
R +FIT+K+ H + + AL +SL K LG D L HS + + + +
Sbjct: 71 RSKLFITSKVM---HNVDNIPEALNESLRK--LGT--DYLDLYLLHSPI--PFYEKKIPI 121
Query: 543 LDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGLEKPSALQIE 680
+ W+ M A GL S+G+SNF ++ ++ + P QIE
Sbjct: 122 SEGWKAMETALGTGLVHSVGVSNFRIPDLEELLKTSTITPRVNQIE 167
>UniRef50_A7RUA2 Cluster: Predicted protein; n=1; Nematostella
vectensis|Rep: Predicted protein - Nematostella
vectensis
Length = 246
Score = 40.3 bits (90), Expect = 0.075
Identities = 32/107 (29%), Positives = 53/107 (49%), Gaps = 1/107 (0%)
Frame = +3
Query: 357 GLKRESIFITTKLWNSYHEREQVIPALRKSLXKSQLGIRRPVFDS-LAHSYV*ERYLARH 533
G+ R+ IFI TKL Y E P L KS+ S + D L HS +
Sbjct: 51 GIPRKDIFIITKLHPRYLGYE---PTL-KSVEMSLRALSTDYIDLFLIHS--------KT 98
Query: 534 VDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGLEKPSALQ 674
+ ++W+ M + + G +S+G+SNFN +++Q +++ SA+Q
Sbjct: 99 GTWKESWKAMEELHRQGKIRSLGVSNFNVDELQELVNFATVPVSAVQ 145
>UniRef50_Q2U219 Cluster: Aldo/keto reductase family proteins; n=6;
Pezizomycotina|Rep: Aldo/keto reductase family proteins
- Aspergillus oryzae
Length = 294
Score = 40.3 bits (90), Expect = 0.075
Identities = 30/108 (27%), Positives = 52/108 (48%)
Frame = +3
Query: 357 GLKRESIFITTKLWNSYHEREQVIPALRKSLXKSQLGIRRPVFDSLAHSYV*ERYLARHV 536
G+ RE +F+TTK+ + + + A+ +SL K QL V L HS +
Sbjct: 79 GIPREELFVTTKVITNIAD---IPSAIDQSLRKLQLNY---VDLYLIHSPF---FAKSDG 129
Query: 537 DFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGLEKPSALQIE 680
+ W M ++ G K+IG+SN++Q ++ + + + P QIE
Sbjct: 130 ELQQAWAAMEKVQQAGKAKAIGVSNYHQSHLEATLKTAVIAPVINQIE 177
Score = 39.5 bits (88), Expect = 0.13
Identities = 20/73 (27%), Positives = 37/73 (50%)
Frame = +2
Query: 140 PTLQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIED 319
P ++L+ +IP++ GT + V + +A+ A+ GY H+D A YG E
Sbjct: 10 PRVKLNDNVSIPILGYGTGTAWYKQAGDDSVNRELVEAIKTAIRLGYRHLDGAEVYGTEA 69
Query: 320 QVGRALXQEILRR 358
++G A+ + + R
Sbjct: 70 ELGVAIKESGIPR 82
>UniRef50_A7ALH6 Cluster: Putative uncharacterized protein; n=1;
Parabacteroides merdae ATCC 43184|Rep: Putative
uncharacterized protein - Parabacteroides merdae ATCC
43184
Length = 301
Score = 39.9 bits (89), Expect = 0.099
Identities = 23/74 (31%), Positives = 42/74 (56%)
Frame = +2
Query: 137 VPTLQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIE 316
VPT++L++G +P + +GT+L V ++ + V +A++ G+ IDTA YG E
Sbjct: 29 VPTVKLNNGMEMPQLGVGTFL----------VKDNAAERVCHAIKVGFRLIDTAQGYGNE 78
Query: 317 DQVGRALXQEILRR 358
+VG + + + R
Sbjct: 79 KEVGEGICRSGIDR 92
Score = 38.7 bits (86), Expect = 0.23
Identities = 30/108 (27%), Positives = 52/108 (48%)
Frame = +3
Query: 357 GLKRESIFITTKLWNSYHEREQVIPALRKSLXKSQLGIRRPVFDSLAHSYV*ERYLARHV 536
G+ R +FITTK+ N+ R + R+SL KS + D + + + H+
Sbjct: 89 GIDRRELFITTKV-NTMEMRGGTV---RQSLDKSLADLGTDYIDLVLIHWP----VKGHI 140
Query: 537 DFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGLEKPSALQIE 680
+TW+ + + G +SIG+SNFN + +++ +P QIE
Sbjct: 141 K--ETWQILEEYVDKGKIRSIGVSNFNPHHLDELLEYARIRPVVNQIE 186
>UniRef50_A5BF24 Cluster: Putative uncharacterized protein; n=1;
Vitis vinifera|Rep: Putative uncharacterized protein -
Vitis vinifera (Grape)
Length = 212
Score = 39.9 bits (89), Expect = 0.099
Identities = 16/47 (34%), Positives = 29/47 (61%)
Frame = +3
Query: 534 VDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGLEKPSALQ 674
+D W+ M D +KL LTK+IG+SNF+ +++ ++ + P+ Q
Sbjct: 116 IDLGSVWKAMEDFQKLSLTKAIGVSNFSCNKLEELLQTASILPAVNQ 162
Score = 33.5 bits (73), Expect = 8.6
Identities = 11/18 (61%), Positives = 16/18 (88%)
Frame = +1
Query: 454 NLNLEYVDLYLIHWPIAM 507
NL L+Y+DLYLIHW +++
Sbjct: 82 NLQLDYLDLYLIHWSVSL 99
>UniRef50_Q4FY75 Cluster: Aldo-keto reductase-like protein; n=5;
Trypanosomatidae|Rep: Aldo-keto reductase-like protein -
Leishmania major strain Friedlin
Length = 372
Score = 39.9 bits (89), Expect = 0.099
Identities = 20/49 (40%), Positives = 27/49 (55%)
Frame = +2
Query: 236 NDTEQAVIYALEAGYTHIDTAYKYGIEDQVGRALXQEILRRT*KRIYLY 382
++ AV +AL GY H+D A YG E VG AL Q + R +R L+
Sbjct: 43 SEATDAVAFALSCGYRHVDCAKAYGNEAAVGEALAQALRTRCTRREDLF 91
Score = 35.5 bits (78), Expect = 2.1
Identities = 13/20 (65%), Positives = 16/20 (80%)
Frame = +1
Query: 448 LXNLNLEYVDLYLIHWPIAM 507
L L L+Y+DLYLIHWP+ M
Sbjct: 114 LAALQLDYLDLYLIHWPVCM 133
>UniRef50_A7D6Q0 Cluster: Aldo/keto reductase; n=1; Halorubrum
lacusprofundi ATCC 49239|Rep: Aldo/keto reductase -
Halorubrum lacusprofundi ATCC 49239
Length = 309
Score = 39.9 bits (89), Expect = 0.099
Identities = 24/69 (34%), Positives = 34/69 (49%)
Frame = +2
Query: 137 VPTLQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIE 316
+PT L SG +P + LGT+ + +V AL +GYTHIDTA Y E
Sbjct: 34 IPTQTLPSGDTLPALGLGTY---------ALDDDQIADSVRAALSSGYTHIDTAEGYHNE 84
Query: 317 DQVGRALXQ 343
+ +G L +
Sbjct: 85 EAIGEVLAE 93
>UniRef50_Q07551 Cluster: NADPH-dependent alpha-keto amide
reductase; n=4; Saccharomycetales|Rep: NADPH-dependent
alpha-keto amide reductase - Saccharomyces cerevisiae
(Baker's yeast)
Length = 312
Score = 39.9 bits (89), Expect = 0.099
Identities = 19/45 (42%), Positives = 25/45 (55%)
Frame = +3
Query: 546 DTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGLEKPSALQIE 680
+ W+ M K G K+IG+SNF E +QRI+ KP QIE
Sbjct: 137 EAWKDMEQLYKSGKAKNIGVSNFAVEDLQRILKVAEVKPQVNQIE 181
Score = 35.1 bits (77), Expect = 2.8
Identities = 14/26 (53%), Positives = 19/26 (73%)
Frame = +2
Query: 689 QPATTELFKFCRENDIXVMAYTPSGP 766
Q T ++KFC+E+DI V AY+P GP
Sbjct: 187 QNQTPGIYKFCQEHDILVEAYSPLGP 212
>UniRef50_UPI0000499B0E Cluster: oxidoreductase, aldo/keto reductase
family; n=1; Entamoeba histolytica HM-1:IMSS|Rep:
oxidoreductase, aldo/keto reductase family - Entamoeba
histolytica HM-1:IMSS
Length = 307
Score = 39.5 bits (88), Expect = 0.13
Identities = 33/115 (28%), Positives = 52/115 (45%), Gaps = 4/115 (3%)
Frame = +3
Query: 348 FSEGLKRESIFITTKLWNSY--HEREQVIPALRKSLXK--SQLGIRRPVFDSLAHSYV*E 515
F + RE +F+T+KLW RE + +++ K I P+ + S +
Sbjct: 64 FLKNHPREELFVTSKLWMDQVTRIRESCLESIQDLKCKYLDLYLIHWPIALKVDASNPPK 123
Query: 516 RYLARHVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGLEKPSALQIE 680
+D + W+ M GL KSIG+SNF QI++I+ KP Q+E
Sbjct: 124 PEDFLDMDITEIWQEMERLVDEGLVKSIGLSNFTIPQIEKIMKMCRIKPVINQVE 178
Score = 34.3 bits (75), Expect = 4.9
Identities = 12/20 (60%), Positives = 17/20 (85%)
Frame = +1
Query: 448 LXNLNLEYVDLYLIHWPIAM 507
+ +L +Y+DLYLIHWPIA+
Sbjct: 95 IQDLKCKYLDLYLIHWPIAL 114
Score = 33.5 bits (73), Expect = 8.6
Identities = 22/68 (32%), Positives = 32/68 (47%)
Frame = +2
Query: 152 LSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQVGR 331
L++G +P + LGTWL + +AV ALE GY ID A Y E ++G
Sbjct: 8 LNNGKFMPAIGLGTWLA---------APGEVGKAVTLALENGYRLIDCARFYKNEKEIGE 58
Query: 332 ALXQEILR 355
+ L+
Sbjct: 59 MGIEPFLK 66
>UniRef50_Q1M4Z6 Cluster: Putative aldo-keto reductase/oxidase; n=1;
Rhizobium leguminosarum bv. viciae 3841|Rep: Putative
aldo-keto reductase/oxidase - Rhizobium leguminosarum
bv. viciae (strain 3841)
Length = 274
Score = 39.5 bits (88), Expect = 0.13
Identities = 18/34 (52%), Positives = 22/34 (64%)
Frame = +2
Query: 236 NDTEQAVIYALEAGYTHIDTAYKYGIEDQVGRAL 337
++ Q VI+ALEAG HIDTA YG E V R +
Sbjct: 23 DEAHQGVIWALEAGCRHIDTAQGYGNEQDVARGI 56
Score = 37.1 bits (82), Expect = 0.70
Identities = 31/100 (31%), Positives = 49/100 (49%), Gaps = 3/100 (3%)
Frame = +3
Query: 357 GLKRESIFITTKLWNSYHEREQVIPALRKSLXKSQLGIRRPVFDSLAHSYV*ERYLARHV 536
G+ R IFITTK+ + V+P++R+SL K +R D L +
Sbjct: 60 GVARNEIFITTKVKPDNYGPGAVMPSVRESLEK----LRVDQVDLLLLHWPSPHNKYPLA 115
Query: 537 DFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQ---RIIDS 647
D+L + + D+ GL + IG+SNF + I R++DS
Sbjct: 116 DYLGQFAEVFDS---GLARQIGVSNFTKAMIDESIRLLDS 152
>UniRef50_Q2H7A8 Cluster: Putative uncharacterized protein; n=1;
Chaetomium globosum|Rep: Putative uncharacterized
protein - Chaetomium globosum (Soil fungus)
Length = 289
Score = 39.5 bits (88), Expect = 0.13
Identities = 33/109 (30%), Positives = 48/109 (44%), Gaps = 1/109 (0%)
Frame = +3
Query: 357 GLKRESIFITTKLWNSYHEREQVIPALRKSLXKSQLGIRRPVFDS-LAHSYV*ERYLARH 533
G+ RE +FIT K+ + E A+ +SL K Q FD L H +
Sbjct: 62 GVPREKLFITNKVAQGIDDIEA---AIDQSLQKMQTNY----FDLYLIHIPF---FAKSE 111
Query: 534 VDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGLEKPSALQIE 680
DF W+ M +K G +SIG+SN+ + I+ + P QIE
Sbjct: 112 EDFQRAWKTMEGIQKAGKARSIGVSNYMRPHIEATLKGATSPPVTNQIE 160
Score = 34.3 bits (75), Expect = 4.9
Identities = 31/103 (30%), Positives = 51/103 (49%)
Frame = +2
Query: 137 VPTLQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIE 316
+P L+L G IP+ T G +G V D +AVI E G+ H+D A YG E
Sbjct: 3 IPLLRLRDGNQIPLDLGDTTFG---QGLV-----DLTKAVI---EKGFYHLDCAEMYGTE 51
Query: 317 DQVGRALXQEILRRT*KRIYLYNYQALEFLPRERASDPSAEEV 445
++V A+ + + R +++++ N A E A D S +++
Sbjct: 52 EEVAIAIKESGVPR--EKLFITNKVAQGIDDIEAAIDQSLQKM 92
>UniRef50_Q8EVT8 Cluster: Oxidoreductase-aldo/keto reductase family;
n=1; Mycoplasma penetrans|Rep: Oxidoreductase-aldo/keto
reductase family - Mycoplasma penetrans
Length = 299
Score = 39.1 bits (87), Expect = 0.17
Identities = 29/102 (28%), Positives = 44/102 (43%)
Frame = +2
Query: 140 PTLQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIED 319
P L L+ G IP++ LGT H K A+ ALE G DTA YG E
Sbjct: 35 PLLTLNDGYQIPIIGLGTTSLHNQTCK---------NAIKAALEIGIRLFDTASLYGNEK 85
Query: 320 QVGRALXQEILRRT*KRIYLYNYQALEFLPRERASDPSAEEV 445
+VG + + + R + Y +F E+A + + ++
Sbjct: 86 EVGETIRESNINRNEIFVITKLYPGAQFANPEKAIEEALNKL 127
>UniRef50_A7BES9 Cluster: Putative uncharacterized protein; n=1;
Actinomyces odontolyticus ATCC 17982|Rep: Putative
uncharacterized protein - Actinomyces odontolyticus ATCC
17982
Length = 282
Score = 39.1 bits (87), Expect = 0.17
Identities = 31/108 (28%), Positives = 50/108 (46%), Gaps = 3/108 (2%)
Frame = +3
Query: 366 RESIFITTKLWNSYHEREQVIPALRKSLXKSQLGI---RRPVFDSLAHSYV*ERYLARHV 536
R+ IF+ TKLW S+ ER + + L + + +P D++A + E+
Sbjct: 65 RDEIFLETKLWPSFFERASAVEETLERLGTDYIDLMILHQPAGDTVAGYRILEK------ 118
Query: 537 DFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGLEKPSALQIE 680
A K G ++IG+SNF+ Q QRI+D P+ Q+E
Sbjct: 119 -----------AHKEGKIRAIGLSNFDVAQTQRILDECEVVPTINQVE 155
Score = 38.3 bits (85), Expect = 0.30
Identities = 26/64 (40%), Positives = 34/64 (53%)
Frame = +2
Query: 146 LQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQV 325
+ L++G IP V LGT+L +D + AV YAL+ YT IDTA Y E V
Sbjct: 4 ITLNNGITIPQVGLGTYLLE---------PDDAQSAVTYALDNDYTLIDTANVYVNERAV 54
Query: 326 GRAL 337
GR +
Sbjct: 55 GRGM 58
>UniRef50_A6WDZ5 Cluster: Aldo/keto reductase; n=5; Bacteria|Rep:
Aldo/keto reductase - Kineococcus radiotolerans SRS30216
Length = 343
Score = 39.1 bits (87), Expect = 0.17
Identities = 25/68 (36%), Positives = 33/68 (48%)
Frame = +2
Query: 134 IVPTLQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGI 313
+VP +L G +P + +GT+ R V AV A+ AGY +D A YG
Sbjct: 12 LVPRRELRGGATVPAIGIGTFGSDRYSPAEVAA------AVAGAVAAGYRLVDCAAVYGN 65
Query: 314 EDQVGRAL 337
E QVG AL
Sbjct: 66 EAQVGEAL 73
>UniRef50_Q5V398 Cluster: Oxidoreductase aldo/keto reductase family;
n=1; Haloarcula marismortui|Rep: Oxidoreductase
aldo/keto reductase family - Haloarcula marismortui
(Halobacterium marismortui)
Length = 302
Score = 39.1 bits (87), Expect = 0.17
Identities = 20/36 (55%), Positives = 23/36 (63%)
Frame = +2
Query: 251 AVIYALEAGYTHIDTAYKYGIEDQVGRALXQEILRR 358
AV AL+ GYTHIDTA Y E VGRA+ Q + R
Sbjct: 38 AVKNALDCGYTHIDTAMAYENEAAVGRAIEQSSVDR 73
>UniRef50_Q11BF8 Cluster: Aldo/keto reductase; n=12; Bacteria|Rep:
Aldo/keto reductase - Mesorhizobium sp. (strain BNC1)
Length = 308
Score = 38.7 bits (86), Expect = 0.23
Identities = 29/108 (26%), Positives = 51/108 (47%)
Frame = +3
Query: 357 GLKRESIFITTKLWNSYHEREQVIPALRKSLXKSQLGIRRPVFDSLAHSYV*ERYLARHV 536
G+ R+ +FI TK+W S + ++ + A KS K LG+ D + + + +
Sbjct: 79 GIARDEVFIETKIWISDYGYDETLHAFDKSAGK--LGV-----DQIDLLLLHQPLPSAFD 131
Query: 537 DFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGLEKPSALQIE 680
L +R + G ++IG+SNF E + R++ P+ QIE
Sbjct: 132 RTLGAYRALEKLLADGKVRAIGVSNFMPEHLTRLLTETSIVPAVNQIE 179
Score = 36.3 bits (80), Expect = 1.2
Identities = 18/41 (43%), Positives = 24/41 (58%)
Frame = +2
Query: 236 NDTEQAVIYALEAGYTHIDTAYKYGIEDQVGRALXQEILRR 358
++T AV AL GY HIDTA YG E +VG + + + R
Sbjct: 42 DETTAAVEEALRLGYRHIDTAAAYGNEREVGEGIRRAGIAR 82
>UniRef50_A3VHZ9 Cluster: Oxidoreductase; n=1; Rhodobacterales
bacterium HTCC2654|Rep: Oxidoreductase - Rhodobacterales
bacterium HTCC2654
Length = 278
Score = 38.7 bits (86), Expect = 0.23
Identities = 23/66 (34%), Positives = 34/66 (51%)
Frame = +2
Query: 140 PTLQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIED 319
PT+ L++G +P + LGTW ++ +AV A+E GY IDTA Y E
Sbjct: 8 PTVTLANGVEMPQLGLGTW---------PMTDDEAAKAVATAIETGYRLIDTAENYKNET 58
Query: 320 QVGRAL 337
VG+ +
Sbjct: 59 GVGQGI 64
>UniRef50_A0JRJ6 Cluster: Aldo/keto reductase; n=2;
Micrococcineae|Rep: Aldo/keto reductase - Arthrobacter
sp. (strain FB24)
Length = 281
Score = 38.7 bits (86), Expect = 0.23
Identities = 28/68 (41%), Positives = 36/68 (52%), Gaps = 1/68 (1%)
Frame = +2
Query: 137 VPTLQLSSGGNIPVVALGTWLGHRPKGKVVQVT-NDTEQAVIYALEAGYTHIDTAYKYGI 313
+P L L++G IP + G V QV +T++ V ALEAGY HIDTA Y
Sbjct: 9 IPQLTLNNGVKIPQLGFG----------VFQVPPEETQRIVEDALEAGYRHIDTAAAYRN 58
Query: 314 EDQVGRAL 337
E VG A+
Sbjct: 59 EAGVGAAI 66
Score = 34.3 bits (75), Expect = 4.9
Identities = 32/110 (29%), Positives = 51/110 (46%)
Frame = +3
Query: 351 SEGLKRESIFITTKLWNSYHEREQVIPALRKSLXKSQLGIRRPVFDSLAHSYV*ERYLAR 530
+ G+ RE IFITTKL N E+ A + S + LG+ V L H V + L
Sbjct: 68 ASGIPREDIFITTKLRNG--EQGNAHEAFQNS--RKALGVEF-VDLYLIHWPVPSQGL-- 120
Query: 531 HVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGLEKPSALQIE 680
+ + W+ M ++IG+SNF E + ++ + P+ Q+E
Sbjct: 121 ---YTEAWKAMEKLYANSQIRAIGVSNFLGEHLDTLLPAADVVPAVNQVE 167
>UniRef50_P91021 Cluster: Putative uncharacterized protein; n=1;
Caenorhabditis elegans|Rep: Putative uncharacterized
protein - Caenorhabditis elegans
Length = 134
Score = 38.7 bits (86), Expect = 0.23
Identities = 27/79 (34%), Positives = 39/79 (49%)
Frame = +2
Query: 146 LQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQV 325
L LS+ ++P V LGTW + D AV A++ GY+ IDTA Y E+ +
Sbjct: 48 LTLSNAHSMPAVGLGTWQSN---------AEDVISAVKAAVKNGYSLIDTASGYNNEEFI 98
Query: 326 GRALXQEILRRT*KRIYLY 382
G A+ + I KR L+
Sbjct: 99 GTAIKEVIAEGVVKREDLF 117
>UniRef50_Q979I4 Cluster: Aldo / keto reductase; n=3; Archaea|Rep:
Aldo / keto reductase - Thermoplasma volcanium
Length = 288
Score = 38.7 bits (86), Expect = 0.23
Identities = 28/100 (28%), Positives = 54/100 (54%)
Frame = +3
Query: 345 KFSEGLKRESIFITTKLWNSYHEREQVIPALRKSLXKSQLGIRRPVFDSLAHSYV*ERYL 524
K EG RE +FI TK+W ++ ++VI A + SL S+L + + L + +
Sbjct: 77 KAIEGHNREELFIATKVWINHLRYDKVIKACKASL--SRLNTK---YVDLYQIH----FP 127
Query: 525 ARHVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIID 644
+ + +T++ M GL K IG+SNF++ ++++ ++
Sbjct: 128 SPTANLQETFKAMEKLVDDGLVKFIGVSNFSRGKLEKSME 167
>UniRef50_Q8G7K9 Cluster: Dehydrogenase or reductase protein; n=4;
Bifidobacterium|Rep: Dehydrogenase or reductase protein
- Bifidobacterium longum
Length = 289
Score = 38.3 bits (85), Expect = 0.30
Identities = 30/67 (44%), Positives = 34/67 (50%)
Frame = +2
Query: 137 VPTLQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIE 316
VP + L G +IP V LG L +G V V + ALEAGY HID A Y E
Sbjct: 11 VPDIALKDGHSIPQVGLGV-LRIDDEGVVPVVES--------ALEAGYRHIDGAAGYNNE 61
Query: 317 DQVGRAL 337
VGRAL
Sbjct: 62 AGVGRAL 68
Score = 33.9 bits (74), Expect = 6.5
Identities = 14/27 (51%), Positives = 17/27 (62%)
Frame = +1
Query: 457 LNLEYVDLYLIHWPIAMFENDTLLDTW 537
L L+YVD+Y+IHWP T DTW
Sbjct: 109 LQLDYVDMYMIHWPTPFDWRST--DTW 133
>UniRef50_Q1PV10 Cluster: Putative uncharacterized protein; n=1;
Candidatus Kuenenia stuttgartiensis|Rep: Putative
uncharacterized protein - Candidatus Kuenenia
stuttgartiensis
Length = 284
Score = 38.3 bits (85), Expect = 0.30
Identities = 28/68 (41%), Positives = 36/68 (52%), Gaps = 6/68 (8%)
Frame = +2
Query: 152 LSSGGNIPVVALGTW-LGHRPKGKVVQVTNDTE--QAVIYALEAGYTHIDTAYKYG---I 313
LS+ IPV+ LGTW +G G T D E A+ A++ G THID A Y
Sbjct: 6 LSNNIKIPVIGLGTWTIG---GGDEADTTYDKENISAIKTAIKLGITHIDNAEAYAQGHS 62
Query: 314 EDQVGRAL 337
E+ VGRA+
Sbjct: 63 EELVGRAI 70
>UniRef50_A1RB46 Cluster: 2,5-diketo-D-gluconate reductase; n=1;
Arthrobacter aurescens TC1|Rep: 2,5-diketo-D-gluconate
reductase - Arthrobacter aurescens (strain TC1)
Length = 273
Score = 38.3 bits (85), Expect = 0.30
Identities = 25/63 (39%), Positives = 33/63 (52%)
Frame = +2
Query: 149 QLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQVG 328
Q S+G +P + LGT G RP D + V +AL+ GY DTA YG E +G
Sbjct: 3 QHSAGTALPAITLGT--GLRPP-------TDVYRLVGWALDMGYRSFDTAALYGTEAAIG 53
Query: 329 RAL 337
RA+
Sbjct: 54 RAI 56
Score = 34.3 bits (75), Expect = 4.9
Identities = 31/108 (28%), Positives = 48/108 (44%), Gaps = 1/108 (0%)
Frame = +3
Query: 357 GLKRESIFITTKL-WNSYHEREQVIPALRKSLXKSQLGIRRPVFDSLAHSYV*ERYLARH 533
G+ R +FIT K+ N Y R +V A+ +SL LG S A V L
Sbjct: 60 GIDRRELFITVKVRGNEYGSRARVHQAIERSL--EALGT------SFADMVVPHWPLPMV 111
Query: 534 VDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGLEKPSALQI 677
T+ M+DA+ GL + +G+SN + ++ + E P Q+
Sbjct: 112 RALPSTFAQMLDARSEGLVRGVGLSNASSAMVRAVRTETGEWPVVNQL 159
>UniRef50_Q5UX52 Cluster: Oxidoreductase aldo/keto reductase family;
n=1; Haloarcula marismortui|Rep: Oxidoreductase
aldo/keto reductase family - Haloarcula marismortui
(Halobacterium marismortui)
Length = 274
Score = 38.3 bits (85), Expect = 0.30
Identities = 24/57 (42%), Positives = 30/57 (52%), Gaps = 1/57 (1%)
Frame = +2
Query: 161 GGNIPVVALGTWLGHRPKGKVVQVTNDT-EQAVIYALEAGYTHIDTAYKYGIEDQVG 328
G ++P + LGTW Q+T + + V AL GY HIDTA YG E QVG
Sbjct: 8 GTSVPALGLGTW----------QLTGQSCRETVETALGMGYRHIDTAQAYGNERQVG 54
Score = 35.9 bits (79), Expect = 1.6
Identities = 30/93 (32%), Positives = 44/93 (47%)
Frame = +3
Query: 366 RESIFITTKLWNSYHEREQVIPALRKSLXKSQLGIRRPVFDSLAHSYV*ERYLARHVDFL 545
RE +F+TTKL S + V + R+SL K LG D L + ++A
Sbjct: 64 REDVFLTTKLDGSNRDERSVRRSTRESLNK--LG--TDYLDLLLIHWPNTPWMA---SLS 116
Query: 546 DTWRGMIDAKKLGLTKSIGISNFNQEQIQRIID 644
+T M D + GL + IG+SNF+ + R D
Sbjct: 117 ETLGAMNDVVEEGLVRHIGVSNFSPSLLDRARD 149
>UniRef50_UPI0000DB6EE9 Cluster: PREDICTED: similar to C35D10.6;
n=2; Endopterygota|Rep: PREDICTED: similar to C35D10.6 -
Apis mellifera
Length = 292
Score = 37.9 bits (84), Expect = 0.40
Identities = 16/45 (35%), Positives = 28/45 (62%), Gaps = 1/45 (2%)
Frame = +3
Query: 549 TWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGLE-KPSALQIE 680
TW ++D KK G +SIG+SNF + +Q ++ + + P+ Q+E
Sbjct: 137 TWNKLVDLKKQGFIRSIGVSNFTIKHLQELLQNCKDILPAVNQVE 181
>UniRef50_Q7NB44 Cluster: ARA1; n=3; Firmicutes|Rep: ARA1 -
Mycoplasma gallisepticum
Length = 289
Score = 37.9 bits (84), Expect = 0.40
Identities = 31/109 (28%), Positives = 47/109 (43%), Gaps = 1/109 (0%)
Frame = +3
Query: 357 GLKRESIFITTKLWNSYHEREQVIPALRKSLXKSQLGIRRPVFDSLAHSYV*ERYLARHV 536
G+ R+ IFIT+K+WN E A K L L + L H + + +
Sbjct: 73 GVNRKEIFITSKIWNDDKGYESTKKAFHKILKDLDLEYLDLL---LIHWPIGKGFKDNWQ 129
Query: 537 DF-LDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGLEKPSALQIE 680
+ TW+ M + G K+IG+SNF I+ + S P Q+E
Sbjct: 130 EVNAQTWKAMEEFYLEGKIKAIGLSNFLVHHIEALKKSAKILPMVNQLE 178
Score = 33.5 bits (73), Expect = 8.6
Identities = 13/18 (72%), Positives = 16/18 (88%)
Frame = +1
Query: 448 LXNLNLEYVDLYLIHWPI 501
L +L+LEY+DL LIHWPI
Sbjct: 103 LKDLDLEYLDLLLIHWPI 120
>UniRef50_Q2CAL9 Cluster: 2,5-didehydrogluconate reductase; n=2;
Oceanicola granulosus HTCC2516|Rep:
2,5-didehydrogluconate reductase - Oceanicola granulosus
HTCC2516
Length = 275
Score = 37.9 bits (84), Expect = 0.40
Identities = 18/40 (45%), Positives = 24/40 (60%)
Frame = +2
Query: 239 DTEQAVIYALEAGYTHIDTAYKYGIEDQVGRALXQEILRR 358
D A++ ALE GY H+DTA Y E +VG A+ + L R
Sbjct: 26 DGISAILCALETGYRHLDTAQDYDTEAEVGEAIRRAGLPR 65
>UniRef50_Q03X85 Cluster: Aldo/keto reductase of diketogulonate
reductase family; n=1; Leuconostoc mesenteroides subsp.
mesenteroides ATCC 8293|Rep: Aldo/keto reductase of
diketogulonate reductase family - Leuconostoc
mesenteroides subsp. mesenteroides (strain ATCC 8293
/NCDO 523)
Length = 288
Score = 37.9 bits (84), Expect = 0.40
Identities = 17/37 (45%), Positives = 25/37 (67%)
Frame = +2
Query: 239 DTEQAVIYALEAGYTHIDTAYKYGIEDQVGRALXQEI 349
+T+QAV+ A+ AGY IDTA YG E + G+ + + I
Sbjct: 26 ETKQAVVDAINAGYRSIDTARVYGNEAETGQGVNEAI 62
Score = 33.9 bits (74), Expect = 6.5
Identities = 29/83 (34%), Positives = 37/83 (44%)
Frame = +3
Query: 366 RESIFITTKLWNSYHEREQVIPALRKSLXKSQLGIRRPVFDSLAHSYV*ERYLARHVDFL 545
RE +F+TTKLW S E A+ SL K LG L Y D
Sbjct: 69 REELFLTTKLWLSEFSYEAAKGAIDDSLKK--LGTDYADLILLHQPY---------GDVY 117
Query: 546 DTWRGMIDAKKLGLTKSIGISNF 614
++ + +A+ G KSIGISNF
Sbjct: 118 GAYKALAEAQADGKVKSIGISNF 140
>UniRef50_A6PR52 Cluster: Aldo/keto reductase; n=1; Victivallis
vadensis ATCC BAA-548|Rep: Aldo/keto reductase -
Victivallis vadensis ATCC BAA-548
Length = 287
Score = 37.9 bits (84), Expect = 0.40
Identities = 27/98 (27%), Positives = 50/98 (51%), Gaps = 4/98 (4%)
Frame = +3
Query: 354 EGLKRESIFITTKLWNSYHEREQVIPALRKSLXKSQLGIRRPVFDSLAHSYV*ERYLARH 533
+G++R F+T K+W ++ + V+ A SL + L Y+ + YL
Sbjct: 76 QGIRRADYFLTDKVWKTHLRYDDVLRAAEASLKR------------LGTDYI-DLYLIHQ 122
Query: 534 VD----FLDTWRGMIDAKKLGLTKSIGISNFNQEQIQR 635
V+ +T R M K+ G+ + IG+SNF++E+++R
Sbjct: 123 VNPDVPEEETIRAMNRLKREGVIRHIGVSNFSEERLKR 160
>UniRef50_A3UJS6 Cluster: Oxidoreductase; n=3;
Alphaproteobacteria|Rep: Oxidoreductase - Oceanicaulis
alexandrii HTCC2633
Length = 275
Score = 37.9 bits (84), Expect = 0.40
Identities = 24/68 (35%), Positives = 32/68 (47%)
Frame = +2
Query: 155 SSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQVGRA 334
++G +IP + GTW D + V AL+ GY HIDTA YG E VG
Sbjct: 7 ANGADIPKLGFGTWQLE---------DEDAARGVATALKTGYRHIDTAQIYGNEAAVGDG 57
Query: 335 LXQEILRR 358
Q ++R
Sbjct: 58 WKQSGVKR 65
Score = 37.1 bits (82), Expect = 0.70
Identities = 24/86 (27%), Positives = 41/86 (47%)
Frame = +3
Query: 357 GLKRESIFITTKLWNSYHEREQVIPALRKSLXKSQLGIRRPVFDSLAHSYV*ERYLARHV 536
G+KRE F+TTK+W + ++++SL K ++ D L + V
Sbjct: 62 GVKREDFFLTTKVWRDKFRDGDLQASVKESLDK----LKTDYVDLLL-----LHWPVPEV 112
Query: 537 DFLDTWRGMIDAKKLGLTKSIGISNF 614
+T + M + K+ G + IG+SNF
Sbjct: 113 PIAETMKAMNEVKEAGQVRHIGVSNF 138
>UniRef50_Q9A2X8 Cluster: Oxidoreductase, aldo/keto reductase
family; n=3; Caulobacter|Rep: Oxidoreductase, aldo/keto
reductase family - Caulobacter crescentus (Caulobacter
vibrioides)
Length = 279
Score = 37.5 bits (83), Expect = 0.53
Identities = 27/76 (35%), Positives = 38/76 (50%), Gaps = 1/76 (1%)
Frame = +2
Query: 134 IVPTLQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIY-ALEAGYTHIDTAYKYG 310
+VP ++ S +P + GTW Q+ N T ++ ALE GY HIDTA YG
Sbjct: 4 LVPAVR-SGDVLMPALGFGTW----------QLENGTAVPLVEKALEIGYRHIDTAQIYG 52
Query: 311 IEDQVGRALXQEILRR 358
E VG A+ ++R
Sbjct: 53 NERDVGAAIRNSGVKR 68
Score = 37.1 bits (82), Expect = 0.70
Identities = 28/94 (29%), Positives = 47/94 (50%)
Frame = +3
Query: 351 SEGLKRESIFITTKLWNSYHEREQVIPALRKSLXKSQLGIRRPVFDSLAHSYV*ERYLAR 530
+ G+KR+ IF+TTK+W + + KSL K LG+ + V L H +
Sbjct: 63 NSGVKRDEIFLTTKVWIDQFADGDLQRSAEKSLEK--LGVDQ-VDLLLLH------WPKP 113
Query: 531 HVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQ 632
V +T + + + G T++IG+SNF Q++
Sbjct: 114 EVPLAETLKALNAVRAKGWTRAIGLSNFPSAQLE 147
>UniRef50_Q5NLW3 Cluster: Putative oxidoreductase; n=1; Zymomonas
mobilis|Rep: Putative oxidoreductase - Zymomonas mobilis
Length = 273
Score = 37.5 bits (83), Expect = 0.53
Identities = 19/46 (41%), Positives = 29/46 (63%), Gaps = 1/46 (2%)
Frame = +3
Query: 546 DTWRGMIDAKKLGLTKSIGISNFNQEQIQRII-DSGLEKPSALQIE 680
+TW+ +I + +G SIG+SNF + + II DSG+ P+ QIE
Sbjct: 117 ETWQTLIQIRAIGKASSIGVSNFTIDHLDHIIADSGV-VPAVNQIE 161
>UniRef50_Q5KCN9 Cluster: Putative uncharacterized protein; n=1;
Filobasidiella neoformans|Rep: Putative uncharacterized
protein - Cryptococcus neoformans (Filobasidiella
neoformans)
Length = 295
Score = 37.5 bits (83), Expect = 0.53
Identities = 35/110 (31%), Positives = 51/110 (46%), Gaps = 2/110 (1%)
Frame = +3
Query: 357 GLKRESIFITTKLWNSY--HEREQVIPALRKSLXKSQLGIRRPVFDSLAHSYV*ERYLAR 530
G KRE IF+ K + E E+ + K L + ++G+ V L HS + A
Sbjct: 65 GGKREDIFLLQKCGSGGGDSESEKNPKVILKGLLQ-EMGVDY-VDLYLLHSPL---LFAP 119
Query: 531 HVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGLEKPSALQIE 680
+ W M + K GL KSIG+SNF +E + + + PS QIE
Sbjct: 120 KYSINEAWAIMEEIKSEGLAKSIGVSNFREEDLMELQKTWKIVPSVNQIE 169
>UniRef50_UPI00005A2CCB Cluster: PREDICTED: similar to Aldose
reductase (AR) (Aldehyde reductase); n=1; Canis lupus
familiaris|Rep: PREDICTED: similar to Aldose reductase
(AR) (Aldehyde reductase) - Canis familiaris
Length = 182
Score = 37.1 bits (82), Expect = 0.70
Identities = 28/106 (26%), Positives = 50/106 (47%)
Frame = +2
Query: 122 SADLIVPTLQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAY 301
S+ ++ L L +G +P++ L TW P KV + AV ++ GY HID +
Sbjct: 15 SSAVLASHLVLGNGIKVPIMGLATWKS--PPSKVTE-------AVKVVMDLGYCHIDCTH 65
Query: 302 KYGIEDQVGRALXQEILRRT*KRIYLYNYQALEFLPRERASDPSAE 439
K + +VG A+ +++ + KR L L+ E+ +A+
Sbjct: 66 KLQNKREVGLAVQEKLKGQGVKREDLSILSELQHTHHEKTCHCAAK 111
>UniRef50_Q7R2T6 Cluster: GLP_291_56367_57278; n=1; Giardia lamblia
ATCC 50803|Rep: GLP_291_56367_57278 - Giardia lamblia
ATCC 50803
Length = 303
Score = 37.1 bits (82), Expect = 0.70
Identities = 16/38 (42%), Positives = 26/38 (68%)
Frame = +3
Query: 351 SEGLKRESIFITTKLWNSYHEREQVIPALRKSLXKSQL 464
S G+KRE ++I +KLW ++HE E+V + ++L QL
Sbjct: 56 SYGVKREDLWIVSKLWPNFHEPEKVAYQISETLRDLQL 93
Score = 33.5 bits (73), Expect = 8.6
Identities = 11/20 (55%), Positives = 18/20 (90%)
Frame = +1
Query: 448 LXNLNLEYVDLYLIHWPIAM 507
L +L LEY+D++L+HWP+A+
Sbjct: 88 LRDLQLEYLDVFLMHWPLAI 107
Database: uniref50
Posted date: Oct 5, 2007 11:19 AM
Number of letters in database: 575,637,011
Number of sequences in database: 1,657,284
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 854,188,186
Number of Sequences: 1657284
Number of extensions: 17767751
Number of successful extensions: 58640
Number of sequences better than 10.0: 309
Number of HSP's better than 10.0 without gapping: 47676
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 54759
length of database: 575,637,011
effective HSP length: 101
effective length of database: 408,251,327
effective search space used: 93081302556
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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