Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= MFBP01_F_I13
(991 letters)
Database: human
237,096 sequences; 76,859,062 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
D17793-1|BAA04619.2| 325|Homo sapiens KIAA0119 protein. 74 7e-13
BT007286-1|AAP35950.1| 323|Homo sapiens aldo-keto reductase fam... 74 7e-13
BC019230-1|AAH19230.1| 323|Homo sapiens aldo-keto reductase fam... 74 7e-13
BC001479-1|AAH01479.1| 323|Homo sapiens aldo-keto reductase fam... 74 7e-13
AL391427-4|CAI14729.1| 323|Homo sapiens aldo-keto reductase fam... 74 7e-13
AB032157-1|BAA92892.1| 323|Homo sapiens prostaglandin F synthas... 74 7e-13
AB018580-1|BAA88488.1| 323|Homo sapiens hluPGFS protein. 74 7e-13
AF149416-1|AAF07272.2| 323|Homo sapiens 3-alpha hydroxysteroid ... 72 3e-12
S68288-1|AAD14011.1| 323|Homo sapiens chlordecone reductase hom... 72 4e-12
DQ269985-1|ABB76132.1| 323|Homo sapiens type II 3a-hydroxystero... 71 5e-12
L43839-1|AAB41916.1| 323|Homo sapiens 3-alpha-hydroxysteroid de... 71 7e-12
U05861-1|AAA18115.1| 323|Homo sapiens hepatic dihydrodiol dehyd... 67 1e-10
U05684-1|AAA16227.1| 323|Homo sapiens dihydrodiol dehydrogenase... 67 1e-10
U05598-1|AAA20937.1| 323|Homo sapiens dihydrodiol dehydrogenase... 67 1e-10
M86609-1|AAB02880.1| 323|Homo sapiens dihydrodiol dehydrogenase... 67 1e-10
D26124-1|BAA05121.1| 306|Homo sapiens dihydrodiol dehydrogenase... 67 1e-10
BT007197-1|AAP35861.1| 323|Homo sapiens aldo-keto reductase fam... 67 1e-10
BT006653-1|AAP35299.1| 323|Homo sapiens aldo-keto reductase fam... 67 1e-10
BC063574-1|AAH63574.1| 323|Homo sapiens aldo-keto reductase fam... 67 1e-10
BC040210-1|AAH40210.1| 323|Homo sapiens aldo-keto reductase fam... 67 1e-10
BC020216-1|AAH20216.1| 323|Homo sapiens aldo-keto reductase fam... 67 1e-10
BC015490-1|AAH15490.1| 323|Homo sapiens aldo-keto reductase fam... 67 1e-10
BC007024-1|AAH07024.1| 323|Homo sapiens aldo-keto reductase fam... 67 1e-10
AL713867-3|CAI16410.1| 247|Homo sapiens aldo-keto reductase fam... 67 1e-10
AL713867-2|CAI16409.1| 323|Homo sapiens aldo-keto reductase fam... 67 1e-10
AL713867-1|CAI16408.1| 323|Homo sapiens aldo-keto reductase fam... 67 1e-10
AL391427-1|CAI14726.1| 323|Homo sapiens aldo-keto reductase fam... 67 1e-10
AB209017-1|BAD92254.1| 286|Homo sapiens aldo-keto reductase fam... 67 1e-10
AB032153-1|BAA92891.1| 323|Homo sapiens bile acid-binding prote... 67 1e-10
AB032150-1|BAA92886.1| 323|Homo sapiens 20 alph-hydroxysteroid ... 67 1e-10
AB031084-1|BAA92884.1| 323|Homo sapiens bile acid-binding prote... 67 1e-10
AB031083-1|BAA92883.1| 323|Homo sapiens 20 alpha-hydroxysteroid... 67 1e-10
AB021654-1|BAA36169.1| 323|Homo sapiens DD2/bile acid-binding p... 67 1e-10
S68330-1|AAD14013.1| 323|Homo sapiens chlordecone reductase hom... 65 3e-10
L32592-1|AAB38486.1| 323|Homo sapiens dihydrodiol dehydrogenase... 65 3e-10
BC020744-1|AAH20744.1| 323|Homo sapiens aldo-keto reductase fam... 62 4e-09
AB045829-1|BAA99542.1| 323|Homo sapiens 3alpha-hydroxysteroid d... 61 5e-09
S68287-1|AAD14010.1| 323|Homo sapiens chlordecone reductase pro... 61 7e-09
M33375-1|AAA35658.1| 308|Homo sapiens protein ( Human chlordeco... 61 7e-09
J04794-1|AAA51711.1| 325|Homo sapiens ALDR1 protein. 61 7e-09
D26125-1|BAA05122.1| 321|Homo sapiens 3 alpha-hydroxysteroid/di... 61 7e-09
CR457010-1|CAG33291.1| 325|Homo sapiens AKR1A1 protein. 61 7e-09
BT007003-1|AAP35649.1| 325|Homo sapiens aldo-keto reductase fam... 61 7e-09
BC005394-1|AAH05394.1| 325|Homo sapiens aldo-keto reductase fam... 61 7e-09
BC000670-1|AAH00670.1| 325|Homo sapiens aldo-keto reductase fam... 61 7e-09
AL355480-3|CAI22459.1| 325|Homo sapiens aldo-keto reductase fam... 61 7e-09
AL355303-2|CAI14202.1| 323|Homo sapiens aldo-keto reductase fam... 61 7e-09
AF112485-1|AAF01260.1| 325|Homo sapiens aldehyde reductase prot... 61 7e-09
AF036683-1|AAB92369.1| 325|Homo sapiens aldehyde reductase prot... 61 7e-09
AB032163-1|BAA92893.1| 323|Homo sapiens dihydrodiol dehydrogena... 61 7e-09
AB031085-1|BAA92885.1| 323|Homo sapiens dihydrodiol dehydrogena... 61 7e-09
S68290-1|AAD14012.1| 320|Homo sapiens chlordecone reductase hom... 59 3e-08
CR542203-1|CAG47000.1| 316|Homo sapiens AKR1B1 protein. 59 3e-08
X15414-1|CAA33460.1| 316|Homo sapiens protein ( Human mRNA for ... 58 7e-08
M59783-1|AAA51712.1| 316|Homo sapiens aldose reductase protein. 58 7e-08
M34720-1|AAA35560.1| 316|Homo sapiens protein ( Human aldose re... 58 7e-08
J05474-1|AAA51715.1| 316|Homo sapiens aldose reductase protein. 58 7e-08
J05017-1|AAA51714.1| 316|Homo sapiens ALDR1 protein. 58 7e-08
J04795-1|AAA51713.1| 316|Homo sapiens ALDR1 protein. 58 7e-08
BT019859-1|AAV38662.1| 316|Homo sapiens aldo-keto reductase fam... 58 7e-08
BC010391-1|AAH10391.1| 316|Homo sapiens aldo-keto reductase fam... 58 7e-08
BC000260-1|AAH00260.1| 316|Homo sapiens aldo-keto reductase fam... 58 7e-08
AF328729-1|AAN09721.1| 316|Homo sapiens CTCL tumor antigen HD-C... 58 7e-08
AF032455-1|AAB88851.1| 316|Homo sapiens aldose reductase protein. 58 7e-08
AB209796-1|BAD93033.1| 260|Homo sapiens aldo-keto reductase fam... 58 7e-08
Z28339-1|CAA82193.1| 326|Homo sapiens delta 4-3-oxosteroid 5 be... 57 9e-08
BC130627-1|AAI30628.1| 326|Homo sapiens aldo-keto reductase fam... 57 9e-08
BC130625-1|AAI30626.1| 326|Homo sapiens aldo-keto reductase fam... 57 9e-08
AF283659-1|AAG39381.1| 326|Homo sapiens 5-beta steroid reductas... 57 9e-08
CR450351-1|CAG29347.1| 316|Homo sapiens AKR1B1 protein. 57 1e-07
U37100-1|AAC17469.1| 316|Homo sapiens aldose reductase-like pep... 55 3e-07
CR541801-1|CAG46600.1| 316|Homo sapiens AKR1B10 protein. 55 3e-07
BT006794-1|AAP35440.1| 316|Homo sapiens aldo-keto reductase fam... 55 3e-07
BC008837-1|AAH08837.1| 316|Homo sapiens aldo-keto reductase fam... 55 3e-07
AF524864-1|AAO13380.1| 316|Homo sapiens aldo-ketoreductase prot... 55 3e-07
AF052577-1|AAC36465.1| 316|Homo sapiens aldo-keto reductase pro... 55 3e-07
BC002862-1|AAH02862.1| 307|Homo sapiens AKR1CL2 protein protein. 54 1e-06
AF263242-1|AAK58523.1| 320|Homo sapiens aldo-keto reductase loo... 54 1e-06
AB055603-1|BAC54568.1| 307|Homo sapiens aldo-keto reductase rel... 54 1e-06
BC005387-1|AAH05387.1| 316|Homo sapiens aldo-keto reductase fam... 52 3e-06
AB040821-1|BAC54566.1| 263|Homo sapiens aldo-keto reductase rel... 52 4e-06
AB040820-1|BAC54565.1| 250|Homo sapiens aldo-keto reductase rel... 52 4e-06
BC101205-1|AAI01206.1| 129|Homo sapiens aldo-keto reductase fam... 48 5e-05
BC101204-1|AAI01205.1| 129|Homo sapiens aldo-keto reductase fam... 48 5e-05
AL391427-2|CAI14727.1| 302|Homo sapiens aldo-keto reductase fam... 48 5e-05
AL355303-1|CAI14201.1| 302|Homo sapiens aldo-keto reductase fam... 48 5e-05
AK131335-1|BAD18494.1| 129|Homo sapiens protein ( Homo sapiens ... 48 5e-05
AL355480-2|CAI22458.1| 147|Homo sapiens aldo-keto reductase fam... 47 9e-05
AB037902-1|BAA92887.1| 130|Homo sapiens truncated aldo-keto red... 45 4e-04
AB028065-1|BAA88489.1| 67|Homo sapiens prostaglandin F synthas... 44 9e-04
AK058142-1|BAB71682.1| 146|Homo sapiens protein ( Homo sapiens ... 43 0.002
AB040822-1|BAC54567.1| 222|Homo sapiens aldo-keto reductase rel... 37 0.099
AJ421033-1|CAD13145.1| 326|Homo sapiens TPIP beta protein. 31 6.5
BC029488-1|AAH29488.1| 294|Homo sapiens sperm acrosome associat... 31 8.6
AL136096-1|CAI19915.1| 294|Homo sapiens sperm acrosome associat... 31 8.6
AF203447-1|AAG31422.1| 294|Homo sapiens sperm acrosome membrane... 31 8.6
>D17793-1|BAA04619.2| 325|Homo sapiens KIAA0119 protein.
Length = 325
Score = 74.1 bits (174), Expect = 7e-13
Identities = 49/125 (39%), Positives = 71/125 (56%), Gaps = 13/125 (10%)
Frame = +3
Query: 345 KFSEG-LKRESIFITTKLWNSYHEREQVIPALRKSLXKSQLG------IRRPVF----DS 491
K ++G +KRE IF T+KLW+++H E V PAL SL K+QL I P+ +
Sbjct: 70 KIADGSVKREDIFYTSKLWSTFHRPELVRPALENSLKKAQLDYVDLYLIHSPMSLKPGEE 129
Query: 492 LAHSYV*ERYLARHVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDS-GLE-KPS 665
L+ + + + VD TW M K GL KSIG+SNFN+ Q++ I++ GL+ KP
Sbjct: 130 LSPTDENGKVIFDIVDLCTTWEAMEKCKDAGLAKSIGVSNFNRRQLEMILNKPGLKYKPV 189
Query: 666 ALQIE 680
Q+E
Sbjct: 190 CNQVE 194
Score = 45.2 bits (102), Expect = 4e-04
Identities = 27/76 (35%), Positives = 44/76 (57%), Gaps = 1/76 (1%)
Frame = +2
Query: 146 LQLSSGGNIPVVALGTWLGHR-PKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQ 322
++L+ G +PV+ GT+ P+ K ++VT A+EAG+ HID+A+ Y E+Q
Sbjct: 10 VKLNDGHFMPVLGFGTYAPPEVPRSKALEVTK-------LAIEAGFRHIDSAHLYNNEEQ 62
Query: 323 VGRALXQEILRRT*KR 370
VG A+ +I + KR
Sbjct: 63 VGLAIRSKIADGSVKR 78
>BT007286-1|AAP35950.1| 323|Homo sapiens aldo-keto reductase family
1, member C3 (3-alpha hydroxysteroid dehydrogenase,
protein.
Length = 323
Score = 74.1 bits (174), Expect = 7e-13
Identities = 49/125 (39%), Positives = 71/125 (56%), Gaps = 13/125 (10%)
Frame = +3
Query: 345 KFSEG-LKRESIFITTKLWNSYHEREQVIPALRKSLXKSQLG------IRRPVF----DS 491
K ++G +KRE IF T+KLW+++H E V PAL SL K+QL I P+ +
Sbjct: 68 KIADGSVKREDIFYTSKLWSTFHRPELVRPALENSLKKAQLDYVDLYLIHSPMSLKPGEE 127
Query: 492 LAHSYV*ERYLARHVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDS-GLE-KPS 665
L+ + + + VD TW M K GL KSIG+SNFN+ Q++ I++ GL+ KP
Sbjct: 128 LSPTDENGKVIFDIVDLCTTWEAMEKCKDAGLAKSIGVSNFNRRQLEMILNKPGLKYKPV 187
Query: 666 ALQIE 680
Q+E
Sbjct: 188 CNQVE 192
Score = 45.2 bits (102), Expect = 4e-04
Identities = 27/76 (35%), Positives = 44/76 (57%), Gaps = 1/76 (1%)
Frame = +2
Query: 146 LQLSSGGNIPVVALGTWLGHR-PKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQ 322
++L+ G +PV+ GT+ P+ K ++VT A+EAG+ HID+A+ Y E+Q
Sbjct: 8 VKLNDGHFMPVLGFGTYAPPEVPRSKALEVTK-------LAIEAGFRHIDSAHLYNNEEQ 60
Query: 323 VGRALXQEILRRT*KR 370
VG A+ +I + KR
Sbjct: 61 VGLAIRSKIADGSVKR 76
>BC019230-1|AAH19230.1| 323|Homo sapiens aldo-keto reductase family
1, member C3 (3-alpha hydroxysteroid dehydrogenase,
protein.
Length = 323
Score = 74.1 bits (174), Expect = 7e-13
Identities = 49/125 (39%), Positives = 71/125 (56%), Gaps = 13/125 (10%)
Frame = +3
Query: 345 KFSEG-LKRESIFITTKLWNSYHEREQVIPALRKSLXKSQLG------IRRPVF----DS 491
K ++G +KRE IF T+KLW+++H E V PAL SL K+QL I P+ +
Sbjct: 68 KIADGSVKREDIFYTSKLWSTFHRPELVRPALENSLKKAQLDYVDLYLIHSPMSLKPGEE 127
Query: 492 LAHSYV*ERYLARHVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDS-GLE-KPS 665
L+ + + + VD TW M K GL KSIG+SNFN+ Q++ I++ GL+ KP
Sbjct: 128 LSPTDENGKVIFDIVDLCTTWEAMEKCKDAGLAKSIGVSNFNRRQLEMILNKPGLKYKPV 187
Query: 666 ALQIE 680
Q+E
Sbjct: 188 CNQVE 192
Score = 45.2 bits (102), Expect = 4e-04
Identities = 27/76 (35%), Positives = 44/76 (57%), Gaps = 1/76 (1%)
Frame = +2
Query: 146 LQLSSGGNIPVVALGTWLGHR-PKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQ 322
++L+ G +PV+ GT+ P+ K ++VT A+EAG+ HID+A+ Y E+Q
Sbjct: 8 VKLNDGHFMPVLGFGTYAPPEVPRSKALEVTK-------LAIEAGFRHIDSAHLYNNEEQ 60
Query: 323 VGRALXQEILRRT*KR 370
VG A+ +I + KR
Sbjct: 61 VGLAIRSKIADGSVKR 76
>BC001479-1|AAH01479.1| 323|Homo sapiens aldo-keto reductase family
1, member C3 (3-alpha hydroxysteroid dehydrogenase,
protein.
Length = 323
Score = 74.1 bits (174), Expect = 7e-13
Identities = 49/125 (39%), Positives = 71/125 (56%), Gaps = 13/125 (10%)
Frame = +3
Query: 345 KFSEG-LKRESIFITTKLWNSYHEREQVIPALRKSLXKSQLG------IRRPVF----DS 491
K ++G +KRE IF T+KLW+++H E V PAL SL K+QL I P+ +
Sbjct: 68 KIADGSVKREDIFYTSKLWSTFHRPELVRPALENSLKKAQLDYVDLYLIHSPMSLKPGEE 127
Query: 492 LAHSYV*ERYLARHVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDS-GLE-KPS 665
L+ + + + VD TW M K GL KSIG+SNFN+ Q++ I++ GL+ KP
Sbjct: 128 LSPTDENGKVIFDIVDLCTTWEAMEKCKDAGLAKSIGVSNFNRRQLEMILNKPGLKYKPV 187
Query: 666 ALQIE 680
Q+E
Sbjct: 188 CNQVE 192
Score = 45.2 bits (102), Expect = 4e-04
Identities = 27/76 (35%), Positives = 44/76 (57%), Gaps = 1/76 (1%)
Frame = +2
Query: 146 LQLSSGGNIPVVALGTWLGHR-PKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQ 322
++L+ G +PV+ GT+ P+ K ++VT A+EAG+ HID+A+ Y E+Q
Sbjct: 8 VKLNDGHFMPVLGFGTYAPPEVPRSKALEVTK-------LAIEAGFRHIDSAHLYNNEEQ 60
Query: 323 VGRALXQEILRRT*KR 370
VG A+ +I + KR
Sbjct: 61 VGLAIRSKIADGSVKR 76
>AL391427-4|CAI14729.1| 323|Homo sapiens aldo-keto reductase family
1, member C3 (3-alpha hydroxysteroid dehydrogenase,
protein.
Length = 323
Score = 74.1 bits (174), Expect = 7e-13
Identities = 49/125 (39%), Positives = 71/125 (56%), Gaps = 13/125 (10%)
Frame = +3
Query: 345 KFSEG-LKRESIFITTKLWNSYHEREQVIPALRKSLXKSQLG------IRRPVF----DS 491
K ++G +KRE IF T+KLW+++H E V PAL SL K+QL I P+ +
Sbjct: 68 KIADGSVKREDIFYTSKLWSTFHRPELVRPALENSLKKAQLDYVDLYLIHSPMSLKPGEE 127
Query: 492 LAHSYV*ERYLARHVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDS-GLE-KPS 665
L+ + + + VD TW M K GL KSIG+SNFN+ Q++ I++ GL+ KP
Sbjct: 128 LSPTDENGKVIFDIVDLCTTWEAMEKCKDAGLAKSIGVSNFNRRQLEMILNKPGLKYKPV 187
Query: 666 ALQIE 680
Q+E
Sbjct: 188 CNQVE 192
Score = 45.2 bits (102), Expect = 4e-04
Identities = 27/76 (35%), Positives = 44/76 (57%), Gaps = 1/76 (1%)
Frame = +2
Query: 146 LQLSSGGNIPVVALGTWLGHR-PKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQ 322
++L+ G +PV+ GT+ P+ K ++VT A+EAG+ HID+A+ Y E+Q
Sbjct: 8 VKLNDGHFMPVLGFGTYAPPEVPRSKALEVTK-------LAIEAGFRHIDSAHLYNNEEQ 60
Query: 323 VGRALXQEILRRT*KR 370
VG A+ +I + KR
Sbjct: 61 VGLAIRSKIADGSVKR 76
>AB032157-1|BAA92892.1| 323|Homo sapiens prostaglandin F synthase
protein.
Length = 323
Score = 74.1 bits (174), Expect = 7e-13
Identities = 49/125 (39%), Positives = 71/125 (56%), Gaps = 13/125 (10%)
Frame = +3
Query: 345 KFSEG-LKRESIFITTKLWNSYHEREQVIPALRKSLXKSQLG------IRRPVF----DS 491
K ++G +KRE IF T+KLW+++H E V PAL SL K+QL I P+ +
Sbjct: 68 KIADGSVKREDIFYTSKLWSTFHRPELVRPALENSLKKAQLDYVDLYLIHSPMSLKPGEE 127
Query: 492 LAHSYV*ERYLARHVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDS-GLE-KPS 665
L+ + + + VD TW M K GL KSIG+SNFN+ Q++ I++ GL+ KP
Sbjct: 128 LSPTDENGKVIFDIVDLCTTWEAMEKCKDAGLAKSIGVSNFNRRQLEMILNKPGLKYKPV 187
Query: 666 ALQIE 680
Q+E
Sbjct: 188 CNQVE 192
Score = 45.2 bits (102), Expect = 4e-04
Identities = 27/76 (35%), Positives = 44/76 (57%), Gaps = 1/76 (1%)
Frame = +2
Query: 146 LQLSSGGNIPVVALGTWLGHR-PKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQ 322
++L+ G +PV+ GT+ P+ K ++VT A+EAG+ HID+A+ Y E+Q
Sbjct: 8 VKLNDGHFMPVLGFGTYAPPEVPRSKALEVTK-------LAIEAGFRHIDSAHLYNNEEQ 60
Query: 323 VGRALXQEILRRT*KR 370
VG A+ +I + KR
Sbjct: 61 VGLAIRSKIADGSVKR 76
>AB018580-1|BAA88488.1| 323|Homo sapiens hluPGFS protein.
Length = 323
Score = 74.1 bits (174), Expect = 7e-13
Identities = 49/125 (39%), Positives = 71/125 (56%), Gaps = 13/125 (10%)
Frame = +3
Query: 345 KFSEG-LKRESIFITTKLWNSYHEREQVIPALRKSLXKSQLG------IRRPVF----DS 491
K ++G +KRE IF T+KLW+++H E V PAL SL K+QL I P+ +
Sbjct: 68 KIADGSVKREDIFYTSKLWSTFHRPELVRPALENSLKKAQLDYVDLYLIHSPMSLKPGEE 127
Query: 492 LAHSYV*ERYLARHVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDS-GLE-KPS 665
L+ + + + VD TW M K GL KSIG+SNFN+ Q++ I++ GL+ KP
Sbjct: 128 LSPTDENGKVIFDIVDLCTTWEAMEKCKDAGLAKSIGVSNFNRRQLEMILNKPGLKYKPV 187
Query: 666 ALQIE 680
Q+E
Sbjct: 188 CNQVE 192
Score = 45.2 bits (102), Expect = 4e-04
Identities = 27/76 (35%), Positives = 44/76 (57%), Gaps = 1/76 (1%)
Frame = +2
Query: 146 LQLSSGGNIPVVALGTWLGHR-PKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQ 322
++L+ G +PV+ GT+ P+ K ++VT A+EAG+ HID+A+ Y E+Q
Sbjct: 8 VKLNDGHFMPVLGFGTYAPPEVPRSKALEVTK-------LAIEAGFRHIDSAHLYNNEEQ 60
Query: 323 VGRALXQEILRRT*KR 370
VG A+ +I + KR
Sbjct: 61 VGLAIRSKIADGSVKR 76
>AF149416-1|AAF07272.2| 323|Homo sapiens 3-alpha hydroxysteroid
dehydrogenase type IIb protein.
Length = 323
Score = 72.1 bits (169), Expect = 3e-12
Identities = 49/125 (39%), Positives = 70/125 (56%), Gaps = 13/125 (10%)
Frame = +3
Query: 345 KFSEG-LKRESIFITTKLWNSYHEREQVIPALRKSLXKSQLG------IRRPVF----DS 491
K ++G +KRE IF T+KLW++ H E V PAL SL K+QL I P+ +
Sbjct: 68 KIADGSVKREDIFYTSKLWSTSHRPELVRPALENSLKKAQLDYVDLYLIHSPMSLKPGEE 127
Query: 492 LAHSYV*ERYLARHVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDS-GLE-KPS 665
L+ + + + VD TW M K GL KSIG+SNFN+ Q++ I++ GL+ KP
Sbjct: 128 LSPTDENGKVIFDIVDLCTTWEAMEKCKDAGLAKSIGVSNFNRRQLEMILNKPGLKYKPV 187
Query: 666 ALQIE 680
Q+E
Sbjct: 188 CNQVE 192
Score = 43.6 bits (98), Expect = 0.001
Identities = 26/76 (34%), Positives = 44/76 (57%), Gaps = 1/76 (1%)
Frame = +2
Query: 146 LQLSSGGNIPVVALGTWLGHR-PKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQ 322
++L+ G +PV+ GT+ P+ K ++V+ A+EAG+ HID+A+ Y E+Q
Sbjct: 8 VKLNDGHFMPVLGFGTYAPPEVPRSKALEVSK-------LAIEAGFRHIDSAHLYNNEEQ 60
Query: 323 VGRALXQEILRRT*KR 370
VG A+ +I + KR
Sbjct: 61 VGLAIRSKIADGSVKR 76
>S68288-1|AAD14011.1| 323|Homo sapiens chlordecone reductase
homolog protein.
Length = 323
Score = 71.7 bits (168), Expect = 4e-12
Identities = 48/125 (38%), Positives = 71/125 (56%), Gaps = 13/125 (10%)
Frame = +3
Query: 345 KFSEG-LKRESIFITTKLWNSYHEREQVIPALRKSLXKSQLG------IRRPVF----DS 491
K ++G ++RE IF T+KLW+++H E V PAL SL K+QL I P+ +
Sbjct: 68 KIADGSVEREDIFYTSKLWSTFHRPELVRPALENSLKKAQLDYVDLYLIHSPMSLKPGEE 127
Query: 492 LAHSYV*ERYLARHVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDS-GLE-KPS 665
L+ + + + VD TW M K GL KSIG+SNFN+ Q++ I++ GL+ KP
Sbjct: 128 LSPTDENGKVIFDIVDLCTTWEAMEKCKDAGLAKSIGVSNFNRRQLEIILNKPGLKYKPV 187
Query: 666 ALQIE 680
Q+E
Sbjct: 188 CNQVE 192
Score = 44.4 bits (100), Expect = 7e-04
Identities = 25/69 (36%), Positives = 41/69 (59%), Gaps = 1/69 (1%)
Frame = +2
Query: 146 LQLSSGGNIPVVALGTWLGHR-PKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQ 322
++L+ G +PV+ GT+ P+ K ++VT A+EAG+ HID+A+ Y E+Q
Sbjct: 8 VKLNDGHFMPVLGFGTYAPPEVPRSKALEVTK-------LAIEAGFRHIDSAHLYNNEEQ 60
Query: 323 VGRALXQEI 349
VG A+ +I
Sbjct: 61 VGLAIRSKI 69
>DQ269985-1|ABB76132.1| 323|Homo sapiens type II 3a-hydroxysteroid
dehydrogenase variant protein.
Length = 323
Score = 71.3 bits (167), Expect = 5e-12
Identities = 49/125 (39%), Positives = 70/125 (56%), Gaps = 13/125 (10%)
Frame = +3
Query: 345 KFSEG-LKRESIFITTKLWNSYHEREQVIPALRKSLXKSQLG------IRRPVF----DS 491
K ++G +KRE IF T+KLW + H E V PAL +SL K+QL I P+ +
Sbjct: 68 KIADGSVKREDIFYTSKLWCNSHRPELVRPALERSLKKAQLDYVDLYLIHSPMSLKPGEE 127
Query: 492 LAHSYV*ERYLARHVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDS-GLE-KPS 665
L+ + + + VD TW M K GL KSIG+SNFN+ Q++ I++ GL+ KP
Sbjct: 128 LSPTDENGKVIFDIVDLCTTWEAMEKCKDAGLAKSIGVSNFNRRQLEMILNKPGLKYKPV 187
Query: 666 ALQIE 680
Q+E
Sbjct: 188 CNQVE 192
Score = 44.8 bits (101), Expect = 5e-04
Identities = 27/76 (35%), Positives = 43/76 (56%), Gaps = 1/76 (1%)
Frame = +2
Query: 146 LQLSSGGNIPVVALGTWL-GHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQ 322
++L+ G +PV+ GT+ PK K ++ T A+EAG+ HID+A+ Y E+Q
Sbjct: 8 VKLNDGHFMPVLGFGTYAPAEVPKSKALEATK-------LAIEAGFRHIDSAHLYNNEEQ 60
Query: 323 VGRALXQEILRRT*KR 370
VG A+ +I + KR
Sbjct: 61 VGLAVRSKIADGSVKR 76
>L43839-1|AAB41916.1| 323|Homo sapiens 3-alpha-hydroxysteroid
dehydrogenase protein.
Length = 323
Score = 70.9 bits (166), Expect = 7e-12
Identities = 48/125 (38%), Positives = 70/125 (56%), Gaps = 13/125 (10%)
Frame = +3
Query: 345 KFSEG-LKRESIFITTKLWNSYHEREQVIPALRKSLXKSQLG------IRRPVF----DS 491
K ++G + RE IF T+KLW+++H E V PAL SL K+QL I P+ +
Sbjct: 68 KIADGSVMREDIFYTSKLWSTFHRPELVRPALENSLKKAQLDYVDLYLIHSPMSLKPGEE 127
Query: 492 LAHSYV*ERYLARHVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDS-GLE-KPS 665
L+ + + + VD TW M K GL KSIG+SNFN+ Q++ I++ GL+ KP
Sbjct: 128 LSPTDENGKVIFDIVDLCTTWEAMEKCKDAGLAKSIGVSNFNRRQLEIILNKPGLKYKPV 187
Query: 666 ALQIE 680
Q+E
Sbjct: 188 CNQVE 192
Score = 44.4 bits (100), Expect = 7e-04
Identities = 25/69 (36%), Positives = 41/69 (59%), Gaps = 1/69 (1%)
Frame = +2
Query: 146 LQLSSGGNIPVVALGTWLGHR-PKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQ 322
++L+ G +PV+ GT+ P+ K ++VT A+EAG+ HID+A+ Y E+Q
Sbjct: 8 VKLNDGHFMPVLGFGTYAPPEVPRSKALEVTK-------LAIEAGFRHIDSAHLYNNEEQ 60
Query: 323 VGRALXQEI 349
VG A+ +I
Sbjct: 61 VGLAIRSKI 69
>U05861-1|AAA18115.1| 323|Homo sapiens hepatic dihydrodiol
dehydrogenase protein.
Length = 323
Score = 66.9 bits (156), Expect = 1e-10
Identities = 48/125 (38%), Positives = 66/125 (52%), Gaps = 13/125 (10%)
Frame = +3
Query: 345 KFSEG-LKRESIFITTKLWNSYHEREQVIPALRKSLXKSQLG------IRRPVFDSLAHS 503
K ++G +KRE IF T+KLW + H E V PAL +SL QL I PV
Sbjct: 68 KIADGSVKREDIFYTSKLWCNSHRPELVRPALERSLKNLQLDYVDLYLIHFPVSVKPGEE 127
Query: 504 YV*E----RYLARHVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDS-GLE-KPS 665
+ + + L VD TW + K GL KSIG+SNFN+ Q++ I++ GL+ KP
Sbjct: 128 VIPKDENGKILFDTVDLCATWEAVEKCKDAGLAKSIGVSNFNRRQLEMILNKPGLKYKPV 187
Query: 666 ALQIE 680
Q+E
Sbjct: 188 CNQVE 192
Score = 45.2 bits (102), Expect = 4e-04
Identities = 27/76 (35%), Positives = 43/76 (56%), Gaps = 1/76 (1%)
Frame = +2
Query: 146 LQLSSGGNIPVVALGTWL-GHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQ 322
++L+ G +PV+ GT+ PK K ++ T A+EAG+ HID+A+ Y E+Q
Sbjct: 8 VKLNDGHFMPVLGFGTYAPAEVPKSKALEATK-------LAIEAGFRHIDSAHLYNNEEQ 60
Query: 323 VGRALXQEILRRT*KR 370
VG A+ +I + KR
Sbjct: 61 VGLAIRSKIADGSVKR 76
>U05684-1|AAA16227.1| 323|Homo sapiens dihydrodiol dehydrogenase
protein.
Length = 323
Score = 66.9 bits (156), Expect = 1e-10
Identities = 48/125 (38%), Positives = 66/125 (52%), Gaps = 13/125 (10%)
Frame = +3
Query: 345 KFSEG-LKRESIFITTKLWNSYHEREQVIPALRKSLXKSQLG------IRRPVFDSLAHS 503
K ++G +KRE IF T+KLW + H E V PAL +SL QL I PV
Sbjct: 68 KIADGSVKREDIFYTSKLWCNSHRPELVRPALERSLKNLQLDYVDLYLIHFPVSVKPGEE 127
Query: 504 YV*E----RYLARHVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDS-GLE-KPS 665
+ + + L VD TW + K GL KSIG+SNFN+ Q++ I++ GL+ KP
Sbjct: 128 VIPKDENGKILFDTVDLCATWEAVEKCKDAGLAKSIGVSNFNRRQLEMILNKPGLKYKPV 187
Query: 666 ALQIE 680
Q+E
Sbjct: 188 CNQVE 192
Score = 45.2 bits (102), Expect = 4e-04
Identities = 27/76 (35%), Positives = 43/76 (56%), Gaps = 1/76 (1%)
Frame = +2
Query: 146 LQLSSGGNIPVVALGTWL-GHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQ 322
++L+ G +PV+ GT+ PK K ++ T A+EAG+ HID+A+ Y E+Q
Sbjct: 8 VKLNDGHFMPVLGFGTYAPAEVPKSKALEATK-------LAIEAGFRHIDSAHLYNNEEQ 60
Query: 323 VGRALXQEILRRT*KR 370
VG A+ +I + KR
Sbjct: 61 VGLAIRSKIADGSVKR 76
>U05598-1|AAA20937.1| 323|Homo sapiens dihydrodiol dehydrogenase
protein.
Length = 323
Score = 66.9 bits (156), Expect = 1e-10
Identities = 48/125 (38%), Positives = 65/125 (52%), Gaps = 13/125 (10%)
Frame = +3
Query: 345 KFSEG-LKRESIFITTKLWNSYHEREQVIPALRKSLXKSQLG------IRRPVFDSLAHS 503
K ++G +KRE IF T+KLW++ H E V PAL +SL QL I PV
Sbjct: 68 KIADGSVKREDIFYTSKLWSNSHRPELVRPALERSLKNLQLDYVDLYLIHFPVSVKPGEE 127
Query: 504 YV*E----RYLARHVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDS-GLE-KPS 665
+ + + L VD TW M K GL KSIG+SNFN ++ I++ GL+ KP
Sbjct: 128 VIPKDENGKILFDTVDLCATWEAMEKCKDAGLAKSIGVSNFNHRLLEMILNKPGLKYKPV 187
Query: 666 ALQIE 680
Q+E
Sbjct: 188 CNQVE 192
Score = 44.8 bits (101), Expect = 5e-04
Identities = 28/76 (36%), Positives = 44/76 (57%), Gaps = 1/76 (1%)
Frame = +2
Query: 146 LQLSSGGNIPVVALGTWL-GHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQ 322
++L+ G +PV+ GT+ PK K ++ AV A+EAG+ HID+A+ Y E+Q
Sbjct: 8 VKLNDGHFMPVLGFGTYAPAEVPKSKALE-------AVKLAIEAGFHHIDSAHVYNNEEQ 60
Query: 323 VGRALXQEILRRT*KR 370
VG A+ +I + KR
Sbjct: 61 VGLAIRSKIADGSVKR 76
>M86609-1|AAB02880.1| 323|Homo sapiens dihydrodiol dehydrogenase
protein.
Length = 323
Score = 66.9 bits (156), Expect = 1e-10
Identities = 48/125 (38%), Positives = 66/125 (52%), Gaps = 13/125 (10%)
Frame = +3
Query: 345 KFSEG-LKRESIFITTKLWNSYHEREQVIPALRKSLXKSQLG------IRRPVFDSLAHS 503
K ++G +KRE IF T+KLW + H E V PAL +SL QL I PV
Sbjct: 68 KIADGSVKREDIFYTSKLWCNSHRPELVRPALERSLKNLQLDYVDLYLIHFPVSVKPGEE 127
Query: 504 YV*E----RYLARHVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDS-GLE-KPS 665
+ + + L VD TW + K GL KSIG+SNFN+ Q++ I++ GL+ KP
Sbjct: 128 VIPKDENGKILFDTVDLCATWEAVEKCKDAGLAKSIGVSNFNRRQLEMILNKPGLKYKPV 187
Query: 666 ALQIE 680
Q+E
Sbjct: 188 CNQVE 192
Score = 45.2 bits (102), Expect = 4e-04
Identities = 27/76 (35%), Positives = 43/76 (56%), Gaps = 1/76 (1%)
Frame = +2
Query: 146 LQLSSGGNIPVVALGTWL-GHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQ 322
++L+ G +PV+ GT+ PK K ++ T A+EAG+ HID+A+ Y E+Q
Sbjct: 8 VKLNDGHFMPVLGFGTYAPAEVPKSKALEATK-------LAIEAGFRHIDSAHLYNNEEQ 60
Query: 323 VGRALXQEILRRT*KR 370
VG A+ +I + KR
Sbjct: 61 VGLAIRSKIADGSVKR 76
>D26124-1|BAA05121.1| 306|Homo sapiens dihydrodiol dehydrogenase
isoform DD1 protein.
Length = 306
Score = 66.9 bits (156), Expect = 1e-10
Identities = 48/125 (38%), Positives = 66/125 (52%), Gaps = 13/125 (10%)
Frame = +3
Query: 345 KFSEG-LKRESIFITTKLWNSYHEREQVIPALRKSLXKSQLG------IRRPVFDSLAHS 503
K ++G +KRE IF T+KLW + H E V PAL +SL QL I PV
Sbjct: 51 KIADGSVKREDIFYTSKLWCNSHRPELVRPALERSLKNLQLDYVDLYLIHFPVSVKPGEE 110
Query: 504 YV*E----RYLARHVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDS-GLE-KPS 665
+ + + L VD TW + K GL KSIG+SNFN+ Q++ I++ GL+ KP
Sbjct: 111 VIPKDENGKILFDTVDLCATWEAVEKCKDAGLAKSIGVSNFNRRQLEMILNKPGLKYKPV 170
Query: 666 ALQIE 680
Q+E
Sbjct: 171 CNQVE 175
Score = 38.7 bits (86), Expect = 0.032
Identities = 24/66 (36%), Positives = 36/66 (54%), Gaps = 1/66 (1%)
Frame = +2
Query: 176 VVALGTWL-GHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQVGRALXQEIL 352
V+ GT+ PK K ++ T A+EAG+ HID+A+ Y E+QVG A+ +I
Sbjct: 1 VLGFGTYAPAEVPKSKALEATK-------LAIEAGFRHIDSAHLYNNEEQVGLAIRSKIA 53
Query: 353 RRT*KR 370
+ KR
Sbjct: 54 DGSVKR 59
>BT007197-1|AAP35861.1| 323|Homo sapiens aldo-keto reductase family
1, member C1 (dihydrodiol dehydrogenase 1; 20-alpha
protein.
Length = 323
Score = 66.9 bits (156), Expect = 1e-10
Identities = 48/125 (38%), Positives = 66/125 (52%), Gaps = 13/125 (10%)
Frame = +3
Query: 345 KFSEG-LKRESIFITTKLWNSYHEREQVIPALRKSLXKSQLG------IRRPVFDSLAHS 503
K ++G +KRE IF T+KLW + H E V PAL +SL QL I PV
Sbjct: 68 KIADGSVKREDIFYTSKLWCNSHRPELVRPALERSLKNLQLDYVDLYLIHFPVSVKPGEE 127
Query: 504 YV*E----RYLARHVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDS-GLE-KPS 665
+ + + L VD TW + K GL KSIG+SNFN+ Q++ I++ GL+ KP
Sbjct: 128 VIPKDENGKILFDTVDLCATWEAVEKCKDAGLAKSIGVSNFNRRQLEMILNKPGLKYKPV 187
Query: 666 ALQIE 680
Q+E
Sbjct: 188 CNQVE 192
Score = 45.2 bits (102), Expect = 4e-04
Identities = 27/76 (35%), Positives = 43/76 (56%), Gaps = 1/76 (1%)
Frame = +2
Query: 146 LQLSSGGNIPVVALGTWL-GHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQ 322
++L+ G +PV+ GT+ PK K ++ T A+EAG+ HID+A+ Y E+Q
Sbjct: 8 VKLNDGHFMPVLGFGTYAPAEVPKSKALEATK-------LAIEAGFRHIDSAHLYNNEEQ 60
Query: 323 VGRALXQEILRRT*KR 370
VG A+ +I + KR
Sbjct: 61 VGLAIRSKIADGSVKR 76
>BT006653-1|AAP35299.1| 323|Homo sapiens aldo-keto reductase family
1, member C2 (dihydrodiol dehydrogenase 2; bile acid
protein.
Length = 323
Score = 66.9 bits (156), Expect = 1e-10
Identities = 48/125 (38%), Positives = 65/125 (52%), Gaps = 13/125 (10%)
Frame = +3
Query: 345 KFSEG-LKRESIFITTKLWNSYHEREQVIPALRKSLXKSQLG------IRRPVFDSLAHS 503
K ++G +KRE IF T+KLW++ H E V PAL +SL QL I PV
Sbjct: 68 KIADGSVKREDIFYTSKLWSNSHRPELVRPALERSLKNLQLDYVDLYLIHFPVSVKPGEE 127
Query: 504 YV*E----RYLARHVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDS-GLE-KPS 665
+ + + L VD TW M K GL KSIG+SNFN ++ I++ GL+ KP
Sbjct: 128 VIPKDENGKILFDTVDLCATWEAMEKCKDAGLAKSIGVSNFNHRLLEMILNKPGLKYKPV 187
Query: 666 ALQIE 680
Q+E
Sbjct: 188 CNQVE 192
Score = 44.8 bits (101), Expect = 5e-04
Identities = 28/76 (36%), Positives = 44/76 (57%), Gaps = 1/76 (1%)
Frame = +2
Query: 146 LQLSSGGNIPVVALGTWL-GHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQ 322
++L+ G +PV+ GT+ PK K ++ AV A+EAG+ HID+A+ Y E+Q
Sbjct: 8 VKLNDGHFMPVLGFGTYAPAEVPKSKALE-------AVKLAIEAGFHHIDSAHVYNNEEQ 60
Query: 323 VGRALXQEILRRT*KR 370
VG A+ +I + KR
Sbjct: 61 VGLAIRSKIADGSVKR 76
>BC063574-1|AAH63574.1| 323|Homo sapiens aldo-keto reductase family
1, member C2 (dihydrodiol dehydrogenase 2; bile acid
protein.
Length = 323
Score = 66.9 bits (156), Expect = 1e-10
Identities = 48/125 (38%), Positives = 65/125 (52%), Gaps = 13/125 (10%)
Frame = +3
Query: 345 KFSEG-LKRESIFITTKLWNSYHEREQVIPALRKSLXKSQLG------IRRPVFDSLAHS 503
K ++G +KRE IF T+KLW++ H E V PAL +SL QL I PV
Sbjct: 68 KIADGSVKREDIFYTSKLWSNSHRPELVRPALERSLKNLQLDYVDLYLIHFPVSVKPGEE 127
Query: 504 YV*E----RYLARHVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDS-GLE-KPS 665
+ + + L VD TW M K GL KSIG+SNFN ++ I++ GL+ KP
Sbjct: 128 VIPKDENGKILFDTVDLCATWEAMEKCKDAGLAKSIGVSNFNHRLLEMILNKPGLKYKPV 187
Query: 666 ALQIE 680
Q+E
Sbjct: 188 CNQVE 192
Score = 44.8 bits (101), Expect = 5e-04
Identities = 28/76 (36%), Positives = 44/76 (57%), Gaps = 1/76 (1%)
Frame = +2
Query: 146 LQLSSGGNIPVVALGTWL-GHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQ 322
++L+ G +PV+ GT+ PK K ++ AV A+EAG+ HID+A+ Y E+Q
Sbjct: 8 VKLNDGHFMPVLGFGTYAPAEVPKSKALE-------AVKLAIEAGFHHIDSAHVYNNEEQ 60
Query: 323 VGRALXQEILRRT*KR 370
VG A+ +I + KR
Sbjct: 61 VGLAIRSKIADGSVKR 76
>BC040210-1|AAH40210.1| 323|Homo sapiens aldo-keto reductase family
1, member C1 (dihydrodiol dehydrogenase 1; 20-alpha
protein.
Length = 323
Score = 66.9 bits (156), Expect = 1e-10
Identities = 48/125 (38%), Positives = 66/125 (52%), Gaps = 13/125 (10%)
Frame = +3
Query: 345 KFSEG-LKRESIFITTKLWNSYHEREQVIPALRKSLXKSQLG------IRRPVFDSLAHS 503
K ++G +KRE IF T+KLW + H E V PAL +SL QL I PV
Sbjct: 68 KIADGSVKREDIFYTSKLWCNSHRPELVRPALERSLKNLQLDYVDLYLIHFPVSVKPGEE 127
Query: 504 YV*E----RYLARHVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDS-GLE-KPS 665
+ + + L VD TW + K GL KSIG+SNFN+ Q++ I++ GL+ KP
Sbjct: 128 VIPKDENGKILFDTVDLCATWEAVEKCKDAGLAKSIGVSNFNRRQLEMILNKPGLKYKPV 187
Query: 666 ALQIE 680
Q+E
Sbjct: 188 CNQVE 192
Score = 45.2 bits (102), Expect = 4e-04
Identities = 27/76 (35%), Positives = 43/76 (56%), Gaps = 1/76 (1%)
Frame = +2
Query: 146 LQLSSGGNIPVVALGTWL-GHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQ 322
++L+ G +PV+ GT+ PK K ++ T A+EAG+ HID+A+ Y E+Q
Sbjct: 8 VKLNDGHFMPVLGFGTYAPAEVPKSKALEATK-------LAIEAGFRHIDSAHLYNNEEQ 60
Query: 323 VGRALXQEILRRT*KR 370
VG A+ +I + KR
Sbjct: 61 VGLAIRSKIADGSVKR 76
>BC020216-1|AAH20216.1| 323|Homo sapiens aldo-keto reductase family
1, member C1 (dihydrodiol dehydrogenase 1; 20-alpha
protein.
Length = 323
Score = 66.9 bits (156), Expect = 1e-10
Identities = 48/125 (38%), Positives = 66/125 (52%), Gaps = 13/125 (10%)
Frame = +3
Query: 345 KFSEG-LKRESIFITTKLWNSYHEREQVIPALRKSLXKSQLG------IRRPVFDSLAHS 503
K ++G +KRE IF T+KLW + H E V PAL +SL QL I PV
Sbjct: 68 KIADGSVKREDIFYTSKLWCNSHRPELVRPALERSLKNLQLDYVDLYLIHFPVSVKPGEE 127
Query: 504 YV*E----RYLARHVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDS-GLE-KPS 665
+ + + L VD TW + K GL KSIG+SNFN+ Q++ I++ GL+ KP
Sbjct: 128 VIPKDENGKILFDTVDLCATWEAVEKCKDAGLAKSIGVSNFNRRQLEMILNKPGLKYKPV 187
Query: 666 ALQIE 680
Q+E
Sbjct: 188 CNQVE 192
Score = 45.2 bits (102), Expect = 4e-04
Identities = 27/76 (35%), Positives = 43/76 (56%), Gaps = 1/76 (1%)
Frame = +2
Query: 146 LQLSSGGNIPVVALGTWL-GHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQ 322
++L+ G +PV+ GT+ PK K ++ T A+EAG+ HID+A+ Y E+Q
Sbjct: 8 VKLNDGHFMPVLGFGTYAPAEVPKSKALEATK-------LAIEAGFRHIDSAHLYNNEEQ 60
Query: 323 VGRALXQEILRRT*KR 370
VG A+ +I + KR
Sbjct: 61 VGLAIRSKIADGSVKR 76
>BC015490-1|AAH15490.1| 323|Homo sapiens aldo-keto reductase family
1, member C1 (dihydrodiol dehydrogenase 1; 20-alpha
protein.
Length = 323
Score = 66.9 bits (156), Expect = 1e-10
Identities = 48/125 (38%), Positives = 66/125 (52%), Gaps = 13/125 (10%)
Frame = +3
Query: 345 KFSEG-LKRESIFITTKLWNSYHEREQVIPALRKSLXKSQLG------IRRPVFDSLAHS 503
K ++G +KRE IF T+KLW + H E V PAL +SL QL I PV
Sbjct: 68 KIADGSVKREDIFYTSKLWCNSHRPELVRPALERSLKNLQLDYVDLYLIHFPVSVKPGEE 127
Query: 504 YV*E----RYLARHVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDS-GLE-KPS 665
+ + + L VD TW + K GL KSIG+SNFN+ Q++ I++ GL+ KP
Sbjct: 128 VIPKDENGKILFDTVDLCATWEAVEKCKDAGLAKSIGVSNFNRRQLEMILNKPGLKYKPV 187
Query: 666 ALQIE 680
Q+E
Sbjct: 188 CNQVE 192
Score = 45.2 bits (102), Expect = 4e-04
Identities = 27/76 (35%), Positives = 43/76 (56%), Gaps = 1/76 (1%)
Frame = +2
Query: 146 LQLSSGGNIPVVALGTWL-GHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQ 322
++L+ G +PV+ GT+ PK K ++ T A+EAG+ HID+A+ Y E+Q
Sbjct: 8 VKLNDGHFMPVLGFGTYAPAEVPKSKALEATK-------LAIEAGFRHIDSAHLYNNEEQ 60
Query: 323 VGRALXQEILRRT*KR 370
VG A+ +I + KR
Sbjct: 61 VGLAIRSKIADGSVKR 76
>BC007024-1|AAH07024.1| 323|Homo sapiens aldo-keto reductase family
1, member C2 (dihydrodiol dehydrogenase 2; bile acid
protein.
Length = 323
Score = 66.9 bits (156), Expect = 1e-10
Identities = 48/125 (38%), Positives = 65/125 (52%), Gaps = 13/125 (10%)
Frame = +3
Query: 345 KFSEG-LKRESIFITTKLWNSYHEREQVIPALRKSLXKSQLG------IRRPVFDSLAHS 503
K ++G +KRE IF T+KLW++ H E V PAL +SL QL I PV
Sbjct: 68 KIADGSVKREDIFYTSKLWSNSHRPELVRPALERSLKNLQLDYVDLYLIHFPVSVKPGEE 127
Query: 504 YV*E----RYLARHVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDS-GLE-KPS 665
+ + + L VD TW M K GL KSIG+SNFN ++ I++ GL+ KP
Sbjct: 128 VIPKDENGKILFDTVDLCATWEAMEKCKDAGLAKSIGVSNFNHRLLEMILNKPGLKYKPV 187
Query: 666 ALQIE 680
Q+E
Sbjct: 188 CNQVE 192
Score = 44.8 bits (101), Expect = 5e-04
Identities = 28/76 (36%), Positives = 44/76 (57%), Gaps = 1/76 (1%)
Frame = +2
Query: 146 LQLSSGGNIPVVALGTWL-GHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQ 322
++L+ G +PV+ GT+ PK K ++ AV A+EAG+ HID+A+ Y E+Q
Sbjct: 8 VKLNDGHFMPVLGFGTYAPAEVPKSKALE-------AVKLAIEAGFHHIDSAHVYNNEEQ 60
Query: 323 VGRALXQEILRRT*KR 370
VG A+ +I + KR
Sbjct: 61 VGLAIRSKIADGSVKR 76
>AL713867-3|CAI16410.1| 247|Homo sapiens aldo-keto reductase family
1, member C1 (dihydrodiol dehydrogenase 1; 20-alpha
protein.
Length = 247
Score = 66.9 bits (156), Expect = 1e-10
Identities = 48/125 (38%), Positives = 66/125 (52%), Gaps = 13/125 (10%)
Frame = +3
Query: 345 KFSEG-LKRESIFITTKLWNSYHEREQVIPALRKSLXKSQLG------IRRPVFDSLAHS 503
K ++G +KRE IF T+KLW + H E V PAL +SL QL I PV
Sbjct: 34 KIADGSVKREDIFYTSKLWCNSHRPELVRPALERSLKNLQLDYVDLYLIHFPVSVKPGEE 93
Query: 504 YV*E----RYLARHVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDS-GLE-KPS 665
+ + + L VD TW + K GL KSIG+SNFN+ Q++ I++ GL+ KP
Sbjct: 94 VIPKDENGKILFDTVDLCATWEAVEKCKDAGLAKSIGVSNFNRRQLEMILNKPGLKYKPV 153
Query: 666 ALQIE 680
Q+E
Sbjct: 154 CNQVE 158
>AL713867-2|CAI16409.1| 323|Homo sapiens aldo-keto reductase family
1, member C1 (dihydrodiol dehydrogenase 1; 20-alpha
protein.
Length = 323
Score = 66.9 bits (156), Expect = 1e-10
Identities = 48/125 (38%), Positives = 66/125 (52%), Gaps = 13/125 (10%)
Frame = +3
Query: 345 KFSEG-LKRESIFITTKLWNSYHEREQVIPALRKSLXKSQLG------IRRPVFDSLAHS 503
K ++G +KRE IF T+KLW + H E V PAL +SL QL I PV
Sbjct: 68 KIADGSVKREDIFYTSKLWCNSHRPELVRPALERSLKNLQLDYVDLYLIHFPVSVKPGEE 127
Query: 504 YV*E----RYLARHVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDS-GLE-KPS 665
+ + + L VD TW + K GL KSIG+SNFN+ Q++ I++ GL+ KP
Sbjct: 128 VIPKDENGKILFDTVDLCATWEAVEKCKDAGLAKSIGVSNFNRRQLEMILNKPGLKYKPV 187
Query: 666 ALQIE 680
Q+E
Sbjct: 188 CNQVE 192
Score = 45.2 bits (102), Expect = 4e-04
Identities = 27/76 (35%), Positives = 43/76 (56%), Gaps = 1/76 (1%)
Frame = +2
Query: 146 LQLSSGGNIPVVALGTWL-GHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQ 322
++L+ G +PV+ GT+ PK K ++ T A+EAG+ HID+A+ Y E+Q
Sbjct: 8 VKLNDGHFMPVLGFGTYAPAEVPKSKALEATK-------LAIEAGFRHIDSAHLYNNEEQ 60
Query: 323 VGRALXQEILRRT*KR 370
VG A+ +I + KR
Sbjct: 61 VGLAIRSKIADGSVKR 76
>AL713867-1|CAI16408.1| 323|Homo sapiens aldo-keto reductase family
1, member C2 (dihydrodiol dehydrogenase 2; bile acid
protein.
Length = 323
Score = 66.9 bits (156), Expect = 1e-10
Identities = 48/125 (38%), Positives = 65/125 (52%), Gaps = 13/125 (10%)
Frame = +3
Query: 345 KFSEG-LKRESIFITTKLWNSYHEREQVIPALRKSLXKSQLG------IRRPVFDSLAHS 503
K ++G +KRE IF T+KLW++ H E V PAL +SL QL I PV
Sbjct: 68 KIADGSVKREDIFYTSKLWSNSHRPELVRPALERSLKNLQLDYVDLYLIHFPVSVKPGEE 127
Query: 504 YV*E----RYLARHVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDS-GLE-KPS 665
+ + + L VD TW M K GL KSIG+SNFN ++ I++ GL+ KP
Sbjct: 128 VIPKDENGKILFDTVDLCATWEAMEKCKDAGLAKSIGVSNFNHRLLEMILNKPGLKYKPV 187
Query: 666 ALQIE 680
Q+E
Sbjct: 188 CNQVE 192
Score = 44.8 bits (101), Expect = 5e-04
Identities = 28/76 (36%), Positives = 44/76 (57%), Gaps = 1/76 (1%)
Frame = +2
Query: 146 LQLSSGGNIPVVALGTWL-GHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQ 322
++L+ G +PV+ GT+ PK K ++ AV A+EAG+ HID+A+ Y E+Q
Sbjct: 8 VKLNDGHFMPVLGFGTYAPAEVPKSKALE-------AVKLAIEAGFHHIDSAHVYNNEEQ 60
Query: 323 VGRALXQEILRRT*KR 370
VG A+ +I + KR
Sbjct: 61 VGLAIRSKIADGSVKR 76
>AL391427-1|CAI14726.1| 323|Homo sapiens aldo-keto reductase family
1, member C2 (dihydrodiol dehydrogenase 2; bile acid
protein.
Length = 323
Score = 66.9 bits (156), Expect = 1e-10
Identities = 48/125 (38%), Positives = 65/125 (52%), Gaps = 13/125 (10%)
Frame = +3
Query: 345 KFSEG-LKRESIFITTKLWNSYHEREQVIPALRKSLXKSQLG------IRRPVFDSLAHS 503
K ++G +KRE IF T+KLW++ H E V PAL +SL QL I PV
Sbjct: 68 KIADGSVKREDIFYTSKLWSNSHRPELVRPALERSLKNLQLDYVDLYLIHFPVSVKPGEE 127
Query: 504 YV*E----RYLARHVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDS-GLE-KPS 665
+ + + L VD TW M K GL KSIG+SNFN ++ I++ GL+ KP
Sbjct: 128 VIPKDENGKILFDTVDLCATWEAMEKCKDAGLAKSIGVSNFNHRLLEMILNKPGLKYKPV 187
Query: 666 ALQIE 680
Q+E
Sbjct: 188 CNQVE 192
Score = 44.8 bits (101), Expect = 5e-04
Identities = 28/76 (36%), Positives = 44/76 (57%), Gaps = 1/76 (1%)
Frame = +2
Query: 146 LQLSSGGNIPVVALGTWL-GHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQ 322
++L+ G +PV+ GT+ PK K ++ AV A+EAG+ HID+A+ Y E+Q
Sbjct: 8 VKLNDGHFMPVLGFGTYAPAEVPKSKALE-------AVKLAIEAGFHHIDSAHVYNNEEQ 60
Query: 323 VGRALXQEILRRT*KR 370
VG A+ +I + KR
Sbjct: 61 VGLAIRSKIADGSVKR 76
>AB209017-1|BAD92254.1| 286|Homo sapiens aldo-keto reductase family
1, member C2 variant protein.
Length = 286
Score = 66.9 bits (156), Expect = 1e-10
Identities = 48/125 (38%), Positives = 65/125 (52%), Gaps = 13/125 (10%)
Frame = +3
Query: 345 KFSEG-LKRESIFITTKLWNSYHEREQVIPALRKSLXKSQLG------IRRPVFDSLAHS 503
K ++G +KRE IF T+KLW++ H E V PAL +SL QL I PV
Sbjct: 81 KIADGSVKREDIFYTSKLWSNSHRPELVRPALERSLKNLQLDYVDLYLIHFPVSVKPGEE 140
Query: 504 YV*E----RYLARHVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDS-GLE-KPS 665
+ + + L VD TW M K GL KSIG+SNFN ++ I++ GL+ KP
Sbjct: 141 VIPKDENGKILFDTVDLCATWEAMEKCKDAGLAKSIGVSNFNHRLLEMILNKPGLKYKPV 200
Query: 666 ALQIE 680
Q+E
Sbjct: 201 CNQVE 205
Score = 45.6 bits (103), Expect = 3e-04
Identities = 30/85 (35%), Positives = 46/85 (54%), Gaps = 1/85 (1%)
Frame = +2
Query: 119 TSADLIVPTLQLSSGGNIPVVALGTWL-GHRPKGKVVQVTNDTEQAVIYALEAGYTHIDT 295
T D ++L+ G +PV+ GT+ PK K ++ AV A+EAG+ HID+
Sbjct: 12 TEMDSKYQCVKLNDGHFMPVLGFGTYAPAEVPKSKALE-------AVKLAIEAGFHHIDS 64
Query: 296 AYKYGIEDQVGRALXQEILRRT*KR 370
A+ Y E+QVG A+ +I + KR
Sbjct: 65 AHVYNNEEQVGLAIRSKIADGSVKR 89
>AB032153-1|BAA92891.1| 323|Homo sapiens bile acid-binding protein
protein.
Length = 323
Score = 66.9 bits (156), Expect = 1e-10
Identities = 48/125 (38%), Positives = 65/125 (52%), Gaps = 13/125 (10%)
Frame = +3
Query: 345 KFSEG-LKRESIFITTKLWNSYHEREQVIPALRKSLXKSQLG------IRRPVFDSLAHS 503
K ++G +KRE IF T+KLW++ H E V PAL +SL QL I PV
Sbjct: 68 KIADGSVKREDIFYTSKLWSNSHRPELVRPALERSLKNLQLDYVDLYLIHFPVSVKPGEE 127
Query: 504 YV*E----RYLARHVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDS-GLE-KPS 665
+ + + L VD TW M K GL KSIG+SNFN ++ I++ GL+ KP
Sbjct: 128 VIPKDENGKILFDTVDLCATWEAMEKCKDAGLAKSIGVSNFNHRLLEMILNKPGLKYKPV 187
Query: 666 ALQIE 680
Q+E
Sbjct: 188 CNQVE 192
Score = 44.8 bits (101), Expect = 5e-04
Identities = 28/76 (36%), Positives = 44/76 (57%), Gaps = 1/76 (1%)
Frame = +2
Query: 146 LQLSSGGNIPVVALGTWL-GHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQ 322
++L+ G +PV+ GT+ PK K ++ AV A+EAG+ HID+A+ Y E+Q
Sbjct: 8 VKLNDGHFMPVLGFGTYAPAEVPKSKALE-------AVKLAIEAGFHHIDSAHVYNNEEQ 60
Query: 323 VGRALXQEILRRT*KR 370
VG A+ +I + KR
Sbjct: 61 VGLAIRSKIADGSVKR 76
>AB032150-1|BAA92886.1| 323|Homo sapiens 20 alph-hydroxysteroid
dehydrogenase protein.
Length = 323
Score = 66.9 bits (156), Expect = 1e-10
Identities = 48/125 (38%), Positives = 66/125 (52%), Gaps = 13/125 (10%)
Frame = +3
Query: 345 KFSEG-LKRESIFITTKLWNSYHEREQVIPALRKSLXKSQLG------IRRPVFDSLAHS 503
K ++G +KRE IF T+KLW + H E V PAL +SL QL I PV
Sbjct: 68 KIADGSVKREDIFYTSKLWCNSHRPELVRPALERSLKNLQLDYVDLYLIHFPVSVKPGEE 127
Query: 504 YV*E----RYLARHVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDS-GLE-KPS 665
+ + + L VD TW + K GL KSIG+SNFN+ Q++ I++ GL+ KP
Sbjct: 128 VIPKDENGKILFDTVDLCATWEAVEKCKDAGLAKSIGVSNFNRRQLEMILNKPGLKYKPV 187
Query: 666 ALQIE 680
Q+E
Sbjct: 188 CNQVE 192
Score = 45.2 bits (102), Expect = 4e-04
Identities = 27/76 (35%), Positives = 43/76 (56%), Gaps = 1/76 (1%)
Frame = +2
Query: 146 LQLSSGGNIPVVALGTWL-GHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQ 322
++L+ G +PV+ GT+ PK K ++ T A+EAG+ HID+A+ Y E+Q
Sbjct: 8 VKLNDGHFMPVLGFGTYAPAEVPKSKALEATK-------LAIEAGFRHIDSAHLYNNEEQ 60
Query: 323 VGRALXQEILRRT*KR 370
VG A+ +I + KR
Sbjct: 61 VGLAIRSKIADGSVKR 76
>AB031084-1|BAA92884.1| 323|Homo sapiens bile acid-binding protein
protein.
Length = 323
Score = 66.9 bits (156), Expect = 1e-10
Identities = 48/125 (38%), Positives = 65/125 (52%), Gaps = 13/125 (10%)
Frame = +3
Query: 345 KFSEG-LKRESIFITTKLWNSYHEREQVIPALRKSLXKSQLG------IRRPVFDSLAHS 503
K ++G +KRE IF T+KLW++ H E V PAL +SL QL I PV
Sbjct: 68 KIADGSVKREDIFYTSKLWSNSHRPELVRPALERSLKNLQLDYVDLYLIHFPVSVKPGEE 127
Query: 504 YV*E----RYLARHVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDS-GLE-KPS 665
+ + + L VD TW M K GL KSIG+SNFN ++ I++ GL+ KP
Sbjct: 128 VIPKDENGKILFDTVDLCATWEAMEKCKDAGLAKSIGVSNFNHRLLEMILNKPGLKYKPV 187
Query: 666 ALQIE 680
Q+E
Sbjct: 188 CNQVE 192
Score = 44.8 bits (101), Expect = 5e-04
Identities = 28/76 (36%), Positives = 44/76 (57%), Gaps = 1/76 (1%)
Frame = +2
Query: 146 LQLSSGGNIPVVALGTWL-GHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQ 322
++L+ G +PV+ GT+ PK K ++ AV A+EAG+ HID+A+ Y E+Q
Sbjct: 8 VKLNDGHFMPVLGFGTYAPAEVPKSKALE-------AVKLAIEAGFHHIDSAHVYNNEEQ 60
Query: 323 VGRALXQEILRRT*KR 370
VG A+ +I + KR
Sbjct: 61 VGLAIRSKIADGSVKR 76
>AB031083-1|BAA92883.1| 323|Homo sapiens 20 alpha-hydroxysteroid
dehydrogenase protein.
Length = 323
Score = 66.9 bits (156), Expect = 1e-10
Identities = 48/125 (38%), Positives = 66/125 (52%), Gaps = 13/125 (10%)
Frame = +3
Query: 345 KFSEG-LKRESIFITTKLWNSYHEREQVIPALRKSLXKSQLG------IRRPVFDSLAHS 503
K ++G +KRE IF T+KLW + H E V PAL +SL QL I PV
Sbjct: 68 KIADGSVKREDIFYTSKLWCNSHRPELVRPALERSLKNLQLDYVDLYLIHFPVSVKPGEE 127
Query: 504 YV*E----RYLARHVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDS-GLE-KPS 665
+ + + L VD TW + K GL KSIG+SNFN+ Q++ I++ GL+ KP
Sbjct: 128 VIPKDENGKILFDTVDLCATWEAVEKCKDAGLAKSIGVSNFNRRQLEMILNKPGLKYKPV 187
Query: 666 ALQIE 680
Q+E
Sbjct: 188 CNQVE 192
Score = 45.2 bits (102), Expect = 4e-04
Identities = 27/76 (35%), Positives = 43/76 (56%), Gaps = 1/76 (1%)
Frame = +2
Query: 146 LQLSSGGNIPVVALGTWL-GHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQ 322
++L+ G +PV+ GT+ PK K ++ T A+EAG+ HID+A+ Y E+Q
Sbjct: 8 VKLNDGHFMPVLGFGTYAPAEVPKSKALEATK-------LAIEAGFRHIDSAHLYNNEEQ 60
Query: 323 VGRALXQEILRRT*KR 370
VG A+ +I + KR
Sbjct: 61 VGLAIRSKIADGSVKR 76
>AB021654-1|BAA36169.1| 323|Homo sapiens DD2/bile acid-binding
protein/AKR1C2/3alpha-hydroxysteroid dehydrogenase type
3 protein.
Length = 323
Score = 66.9 bits (156), Expect = 1e-10
Identities = 48/125 (38%), Positives = 65/125 (52%), Gaps = 13/125 (10%)
Frame = +3
Query: 345 KFSEG-LKRESIFITTKLWNSYHEREQVIPALRKSLXKSQLG------IRRPVFDSLAHS 503
K ++G +KRE IF T+KLW++ H E V PAL +SL QL I PV
Sbjct: 68 KIADGSVKREDIFYTSKLWSNSHRPELVRPALERSLKNLQLDYVDLYLIHFPVSVKPGEE 127
Query: 504 YV*E----RYLARHVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDS-GLE-KPS 665
+ + + L VD TW M K GL KSIG+SNFN ++ I++ GL+ KP
Sbjct: 128 VIPKDENGKILFDTVDLCATWEAMEKCKDAGLAKSIGVSNFNHRLLEMILNKPGLKYKPV 187
Query: 666 ALQIE 680
Q+E
Sbjct: 188 CNQVE 192
Score = 44.8 bits (101), Expect = 5e-04
Identities = 28/76 (36%), Positives = 44/76 (57%), Gaps = 1/76 (1%)
Frame = +2
Query: 146 LQLSSGGNIPVVALGTWL-GHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQ 322
++L+ G +PV+ GT+ PK K ++ AV A+EAG+ HID+A+ Y E+Q
Sbjct: 8 VKLNDGHFMPVLGFGTYAPAEVPKSKALE-------AVKLAIEAGFHHIDSAHVYNNEEQ 60
Query: 323 VGRALXQEILRRT*KR 370
VG A+ +I + KR
Sbjct: 61 VGLAIRSKIADGSVKR 76
>S68330-1|AAD14013.1| 323|Homo sapiens chlordecone reductase
homolog protein.
Length = 323
Score = 65.3 bits (152), Expect = 3e-10
Identities = 47/125 (37%), Positives = 65/125 (52%), Gaps = 13/125 (10%)
Frame = +3
Query: 345 KFSEG-LKRESIFITTKLWNSYHEREQVIPALRKSLXKSQLG------IRRPVFDSLAHS 503
K ++G +KRE IF T+KLW++ H E V PAL +SL QL I PV
Sbjct: 68 KIADGSVKREDIFYTSKLWSNSHRPELVRPALERSLKNLQLDYVDLYLIHFPVSVKPGEE 127
Query: 504 YV*E----RYLARHVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRII-DSGLE-KPS 665
+ + + L VD TW M K GL KSIG+SNFN ++ I+ + GL+ +P
Sbjct: 128 VIPKDENGKILFDTVDLCATWEAMEKCKDAGLAKSIGVSNFNHRLLEMILNEPGLKYEPV 187
Query: 666 ALQIE 680
Q+E
Sbjct: 188 CNQVE 192
Score = 44.8 bits (101), Expect = 5e-04
Identities = 28/76 (36%), Positives = 44/76 (57%), Gaps = 1/76 (1%)
Frame = +2
Query: 146 LQLSSGGNIPVVALGTWL-GHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQ 322
++L+ G +PV+ GT+ PK K ++ AV A+EAG+ HID+A+ Y E+Q
Sbjct: 8 VKLNDGHFMPVLGFGTYAPAEVPKSKALE-------AVKLAIEAGFHHIDSAHVYNNEEQ 60
Query: 323 VGRALXQEILRRT*KR 370
VG A+ +I + KR
Sbjct: 61 VGLAIRSKIADGSVKR 76
>L32592-1|AAB38486.1| 323|Homo sapiens dihydrodiol
dehydrogenase/bile acid-binding protein protein.
Length = 323
Score = 65.3 bits (152), Expect = 3e-10
Identities = 47/125 (37%), Positives = 65/125 (52%), Gaps = 13/125 (10%)
Frame = +3
Query: 345 KFSEG-LKRESIFITTKLWNSYHEREQVIPALRKSLXKSQLG------IRRPVFDSLAHS 503
K ++G +KRE IF T+KLW++ H E V PAL +SL QL I PV
Sbjct: 68 KIADGSVKREDIFYTSKLWSNSHRPELVRPALERSLKNLQLDYADLYLIHFPVSVKPGEE 127
Query: 504 YV*E----RYLARHVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRII-DSGLE-KPS 665
+ + + L VD TW M K GL KSIG+SNFN ++ I+ + GL+ +P
Sbjct: 128 VIPKDENGKILFDTVDLCATWEAMEKCKDAGLAKSIGVSNFNHRLLEMILNEPGLKYEPV 187
Query: 666 ALQIE 680
Q+E
Sbjct: 188 CNQVE 192
Score = 46.4 bits (105), Expect = 2e-04
Identities = 29/76 (38%), Positives = 44/76 (57%), Gaps = 1/76 (1%)
Frame = +2
Query: 146 LQLSSGGNIPVVALGTWL-GHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQ 322
++L+ G +PV+ GT+ PK K ++ AV A+EAGY HID+A+ Y E+Q
Sbjct: 8 VKLNDGHFMPVLGFGTYAPAEVPKSKALE-------AVKLAIEAGYHHIDSAHVYNNEEQ 60
Query: 323 VGRALXQEILRRT*KR 370
VG A+ +I + KR
Sbjct: 61 VGLAIRSKIADGSVKR 76
>BC020744-1|AAH20744.1| 323|Homo sapiens aldo-keto reductase family
1, member C4 (chlordecone reductase; 3-alpha hydroxy
protein.
Length = 323
Score = 61.7 bits (143), Expect = 4e-09
Identities = 45/125 (36%), Positives = 67/125 (53%), Gaps = 13/125 (10%)
Frame = +3
Query: 345 KFSEG-LKRESIFITTKLWNSYHEREQVIPALRKSLXKSQLG------IRRPVFDSLAHS 503
K ++G +KRE IF T+KLW ++ + + V PAL SL K QL + P+ +
Sbjct: 68 KIADGSVKREDIFYTSKLWCTFFQPQMVQPALESSLKKLQLDYVDLYLLHFPMALKPGET 127
Query: 504 YV*E----RYLARHVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDS-GLE-KPS 665
+ + + + VD TW M K GL KSIG+SNFN Q++ I++ GL+ KP
Sbjct: 128 PLPKDENGKVIFDTVDLSATWEVMEKCKDAGLAKSIGVSNFNYRQLEMILNKPGLKYKPV 187
Query: 666 ALQIE 680
Q+E
Sbjct: 188 CNQVE 192
Score = 47.6 bits (108), Expect = 7e-05
Identities = 28/76 (36%), Positives = 44/76 (57%), Gaps = 1/76 (1%)
Frame = +2
Query: 146 LQLSSGGNIPVVALGTWLGHR-PKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQ 322
++L+ G +PV+ GT+ P+ + V+VT A+EAG+ HID+AY Y E+Q
Sbjct: 8 VELNDGHFMPVLGFGTYAPPEVPRNRAVEVTK-------LAIEAGFRHIDSAYLYNNEEQ 60
Query: 323 VGRALXQEILRRT*KR 370
VG A+ +I + KR
Sbjct: 61 VGLAIRSKIADGSVKR 76
Score = 35.1 bits (77), Expect = 0.40
Identities = 15/29 (51%), Positives = 21/29 (72%)
Frame = +1
Query: 442 SPLXNLNLEYVDLYLIHWPIAMFENDTLL 528
S L L L+YVDLYL+H+P+A+ +T L
Sbjct: 101 SSLKKLQLDYVDLYLLHFPMALKPGETPL 129
>AB045829-1|BAA99542.1| 323|Homo sapiens 3alpha-hydroxysteroid
dehydrogenase variant protein.
Length = 323
Score = 61.3 bits (142), Expect = 5e-09
Identities = 45/125 (36%), Positives = 67/125 (53%), Gaps = 13/125 (10%)
Frame = +3
Query: 345 KFSEG-LKRESIFITTKLWNSYHEREQVIPALRKSLXKSQLG------IRRPVFDSLAHS 503
K ++G +KRE IF T+KLW ++ + + V PAL SL K QL + P+ +
Sbjct: 68 KIADGSVKREDIFYTSKLWCTFFQPQMVQPALESSLKKLQLDYVDLYLLHFPMALKPGET 127
Query: 504 YV*E----RYLARHVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDS-GLE-KPS 665
+ + + + VD TW M K GL KSIG+SNFN Q++ I++ GL+ KP
Sbjct: 128 PLPKDENGKVIFDTVDLCATWEVMEKCKDAGLAKSIGVSNFNCRQLEMILNKPGLKYKPV 187
Query: 666 ALQIE 680
Q+E
Sbjct: 188 CNQVE 192
Score = 47.6 bits (108), Expect = 7e-05
Identities = 28/76 (36%), Positives = 44/76 (57%), Gaps = 1/76 (1%)
Frame = +2
Query: 146 LQLSSGGNIPVVALGTWLGHR-PKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQ 322
++L+ G +PV+ GT+ P+ + V+VT A+EAG+ HID+AY Y E+Q
Sbjct: 8 VELNDGHFMPVLGFGTYAPPEVPRNRAVEVTK-------LAIEAGFRHIDSAYLYNNEEQ 60
Query: 323 VGRALXQEILRRT*KR 370
VG A+ +I + KR
Sbjct: 61 VGLAIRSKIADGSVKR 76
Score = 35.1 bits (77), Expect = 0.40
Identities = 15/29 (51%), Positives = 21/29 (72%)
Frame = +1
Query: 442 SPLXNLNLEYVDLYLIHWPIAMFENDTLL 528
S L L L+YVDLYL+H+P+A+ +T L
Sbjct: 101 SSLKKLQLDYVDLYLLHFPMALKPGETPL 129
>S68287-1|AAD14010.1| 323|Homo sapiens chlordecone reductase
protein.
Length = 323
Score = 60.9 bits (141), Expect = 7e-09
Identities = 45/125 (36%), Positives = 67/125 (53%), Gaps = 13/125 (10%)
Frame = +3
Query: 345 KFSEG-LKRESIFITTKLWNSYHEREQVIPALRKSLXKSQLG------IRRPVFDSLAHS 503
K ++G +KRE IF T+KLW ++ + + V PAL SL K QL + P+ +
Sbjct: 68 KIADGSVKREDIFYTSKLWCTFFQPQMVQPALESSLKKLQLDYVDLYLLHFPMALKPGET 127
Query: 504 YV*E----RYLARHVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDS-GLE-KPS 665
+ + + + VD TW M K GL KSIG+SNFN Q++ I++ GL+ KP
Sbjct: 128 PLPKDENGKVIFDTVDLSATWEVMEKCKDAGLAKSIGVSNFNCRQLEMILNKPGLKYKPV 187
Query: 666 ALQIE 680
Q+E
Sbjct: 188 CNQVE 192
Score = 47.6 bits (108), Expect = 7e-05
Identities = 28/76 (36%), Positives = 44/76 (57%), Gaps = 1/76 (1%)
Frame = +2
Query: 146 LQLSSGGNIPVVALGTWLGHR-PKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQ 322
++L+ G +PV+ GT+ P+ + V+VT A+EAG+ HID+AY Y E+Q
Sbjct: 8 VELNDGHFMPVLGFGTYAPPEVPRNRAVEVTK-------LAIEAGFRHIDSAYLYNNEEQ 60
Query: 323 VGRALXQEILRRT*KR 370
VG A+ +I + KR
Sbjct: 61 VGLAIRSKIADGSVKR 76
Score = 35.1 bits (77), Expect = 0.40
Identities = 15/29 (51%), Positives = 21/29 (72%)
Frame = +1
Query: 442 SPLXNLNLEYVDLYLIHWPIAMFENDTLL 528
S L L L+YVDLYL+H+P+A+ +T L
Sbjct: 101 SSLKKLQLDYVDLYLLHFPMALKPGETPL 129
>M33375-1|AAA35658.1| 308|Homo sapiens protein ( Human chlordecone
reductase mRNA, complete cds. ).
Length = 308
Score = 60.9 bits (141), Expect = 7e-09
Identities = 45/125 (36%), Positives = 67/125 (53%), Gaps = 13/125 (10%)
Frame = +3
Query: 345 KFSEG-LKRESIFITTKLWNSYHEREQVIPALRKSLXKSQLG------IRRPVFDSLAHS 503
K ++G +KRE IF T+KLW ++ + + V PAL SL K QL + P+ +
Sbjct: 53 KIADGSVKREDIFYTSKLWCTFFQPQMVQPALESSLKKLQLDYVDLYLLHFPMALKPGET 112
Query: 504 YV*E----RYLARHVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDS-GLE-KPS 665
+ + + + VD TW M K GL KSIG+SNFN Q++ I++ GL+ KP
Sbjct: 113 PLPKDENGKVIFDTVDLSATWEVMEKCKDAGLAKSIGVSNFNCRQLEMILNKPGLKYKPV 172
Query: 666 ALQIE 680
Q+E
Sbjct: 173 CNQVE 177
Score = 44.0 bits (99), Expect = 9e-04
Identities = 26/68 (38%), Positives = 39/68 (57%), Gaps = 1/68 (1%)
Frame = +2
Query: 170 IPVVALGTWLGHR-PKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQVGRALXQE 346
+PV+ GT+ P+ + V+VT A+EAG+ HID+AY Y E+QVG A+ +
Sbjct: 1 MPVLGFGTYAPPEVPRNRAVEVTK-------LAIEAGFRHIDSAYLYNNEEQVGLAIRSK 53
Query: 347 ILRRT*KR 370
I + KR
Sbjct: 54 IADGSVKR 61
Score = 35.1 bits (77), Expect = 0.40
Identities = 15/29 (51%), Positives = 21/29 (72%)
Frame = +1
Query: 442 SPLXNLNLEYVDLYLIHWPIAMFENDTLL 528
S L L L+YVDLYL+H+P+A+ +T L
Sbjct: 86 SSLKKLQLDYVDLYLLHFPMALKPGETPL 114
>J04794-1|AAA51711.1| 325|Homo sapiens ALDR1 protein.
Length = 325
Score = 60.9 bits (141), Expect = 7e-09
Identities = 36/119 (30%), Positives = 61/119 (51%), Gaps = 10/119 (8%)
Frame = +3
Query: 354 EGLKRESIFITTKLWNSYHEREQVIPALRKSLXKSQLGIRRPVFDSLAHSYV-*ERYLAR 530
+ + RE +F+T+KLWN+ H E V PALRK+L QL +++ + +
Sbjct: 68 KAVPREELFVTSKLWNTKHHPEDVEPALRKTLADLQLEYLDLYLMHWPYAFERGDNPFPK 127
Query: 531 HVD---------FLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGLEKPSALQIE 680
+ D + +TW+ + GL +++G+SNFN QI I+ +P+ LQ+E
Sbjct: 128 NADGTICYDSTHYKETWKALEALVAKGLVQALGLSNFNSRQIDDILSVASVRPAVLQVE 186
Score = 47.2 bits (107), Expect = 9e-05
Identities = 27/66 (40%), Positives = 38/66 (57%)
Frame = +2
Query: 152 LSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQVGR 331
L +G +P++ LGTW K + QV + AV YAL GY HID A YG E ++G
Sbjct: 8 LHTGQKMPLIGLGTW-----KSEPGQV----KAAVKYALSVGYRHIDCAAIYGNEPEIGE 58
Query: 332 ALXQEI 349
AL +++
Sbjct: 59 ALKEDV 64
Score = 35.9 bits (79), Expect = 0.23
Identities = 14/24 (58%), Positives = 17/24 (70%)
Frame = +1
Query: 448 LXNLNLEYVDLYLIHWPIAMFEND 519
L +L LEY+DLYL+HWP A D
Sbjct: 99 LADLQLEYLDLYLMHWPYAFERGD 122
>D26125-1|BAA05122.1| 321|Homo sapiens 3
alpha-hydroxysteroid/dihydrodiol dehydrogenase DD4
protein.
Length = 321
Score = 60.9 bits (141), Expect = 7e-09
Identities = 45/125 (36%), Positives = 67/125 (53%), Gaps = 13/125 (10%)
Frame = +3
Query: 345 KFSEG-LKRESIFITTKLWNSYHEREQVIPALRKSLXKSQLG------IRRPVFDSLAHS 503
K ++G +KRE IF T+KLW ++ + + V PAL SL K QL + P+ +
Sbjct: 66 KIADGSVKREDIFYTSKLWCTFFQPQMVQPALESSLKKLQLDYVDLYLLHFPMALKPGET 125
Query: 504 YV*E----RYLARHVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDS-GLE-KPS 665
+ + + + VD TW M K GL KSIG+SNFN Q++ I++ GL+ KP
Sbjct: 126 PLPKDENGKVIFDTVDLSATWEVMEKCKDAGLAKSIGVSNFNCRQLEMILNKPGLKYKPV 185
Query: 666 ALQIE 680
Q+E
Sbjct: 186 CNQVE 190
Score = 47.6 bits (108), Expect = 7e-05
Identities = 28/76 (36%), Positives = 44/76 (57%), Gaps = 1/76 (1%)
Frame = +2
Query: 146 LQLSSGGNIPVVALGTWLGHR-PKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQ 322
++L+ G +PV+ GT+ P+ + V+VT A+EAG+ HID+AY Y E+Q
Sbjct: 6 VELNDGHFMPVLGFGTYAPPEVPRNRAVEVTK-------LAIEAGFRHIDSAYLYNNEEQ 58
Query: 323 VGRALXQEILRRT*KR 370
VG A+ +I + KR
Sbjct: 59 VGLAIRSKIADGSVKR 74
Score = 35.1 bits (77), Expect = 0.40
Identities = 15/29 (51%), Positives = 21/29 (72%)
Frame = +1
Query: 442 SPLXNLNLEYVDLYLIHWPIAMFENDTLL 528
S L L L+YVDLYL+H+P+A+ +T L
Sbjct: 99 SSLKKLQLDYVDLYLLHFPMALKPGETPL 127
>CR457010-1|CAG33291.1| 325|Homo sapiens AKR1A1 protein.
Length = 325
Score = 60.9 bits (141), Expect = 7e-09
Identities = 36/119 (30%), Positives = 61/119 (51%), Gaps = 10/119 (8%)
Frame = +3
Query: 354 EGLKRESIFITTKLWNSYHEREQVIPALRKSLXKSQLGIRRPVFDSLAHSYV-*ERYLAR 530
+ + RE +F+T+KLWN+ H E V PALRK+L QL +++ + +
Sbjct: 68 KAVPREELFVTSKLWNTKHHPEDVEPALRKTLADLQLEYLDLYLMHWPYAFERGDNPFPK 127
Query: 531 HVD---------FLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGLEKPSALQIE 680
+ D + +TW+ + GL +++G+SNFN QI I+ +P+ LQ+E
Sbjct: 128 NADGTICYDSTHYKETWKALEALVAKGLVQALGLSNFNSRQIDDILSVASVRPAVLQVE 186
Score = 47.2 bits (107), Expect = 9e-05
Identities = 27/66 (40%), Positives = 38/66 (57%)
Frame = +2
Query: 152 LSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQVGR 331
L +G +P++ LGTW K + QV + AV YAL GY HID A YG E ++G
Sbjct: 8 LHTGQKMPLIGLGTW-----KSEPGQV----KAAVKYALSVGYRHIDCAAIYGNEPEIGE 58
Query: 332 ALXQEI 349
AL +++
Sbjct: 59 ALKEDV 64
Score = 35.9 bits (79), Expect = 0.23
Identities = 14/24 (58%), Positives = 17/24 (70%)
Frame = +1
Query: 448 LXNLNLEYVDLYLIHWPIAMFEND 519
L +L LEY+DLYL+HWP A D
Sbjct: 99 LADLQLEYLDLYLMHWPYAFERGD 122
>BT007003-1|AAP35649.1| 325|Homo sapiens aldo-keto reductase family
1, member A1 (aldehyde reductase) protein.
Length = 325
Score = 60.9 bits (141), Expect = 7e-09
Identities = 36/119 (30%), Positives = 61/119 (51%), Gaps = 10/119 (8%)
Frame = +3
Query: 354 EGLKRESIFITTKLWNSYHEREQVIPALRKSLXKSQLGIRRPVFDSLAHSYV-*ERYLAR 530
+ + RE +F+T+KLWN+ H E V PALRK+L QL +++ + +
Sbjct: 68 KAVPREELFVTSKLWNTKHHPEDVEPALRKTLADLQLEYLDLYLMHWPYAFERGDNPFPK 127
Query: 531 HVD---------FLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGLEKPSALQIE 680
+ D + +TW+ + GL +++G+SNFN QI I+ +P+ LQ+E
Sbjct: 128 NADGTICYDSTHYKETWKALEALVAKGLVQALGLSNFNSRQIDDILSVASVRPAVLQVE 186
Score = 47.2 bits (107), Expect = 9e-05
Identities = 27/66 (40%), Positives = 38/66 (57%)
Frame = +2
Query: 152 LSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQVGR 331
L +G +P++ LGTW K + QV + AV YAL GY HID A YG E ++G
Sbjct: 8 LHTGQKMPLIGLGTW-----KSEPGQV----KAAVKYALSVGYRHIDCAAIYGNEPEIGE 58
Query: 332 ALXQEI 349
AL +++
Sbjct: 59 ALKEDV 64
Score = 35.9 bits (79), Expect = 0.23
Identities = 14/24 (58%), Positives = 17/24 (70%)
Frame = +1
Query: 448 LXNLNLEYVDLYLIHWPIAMFEND 519
L +L LEY+DLYL+HWP A D
Sbjct: 99 LADLQLEYLDLYLMHWPYAFERGD 122
>BC005394-1|AAH05394.1| 325|Homo sapiens aldo-keto reductase family
1, member A1 (aldehyde reductase) protein.
Length = 325
Score = 60.9 bits (141), Expect = 7e-09
Identities = 36/119 (30%), Positives = 61/119 (51%), Gaps = 10/119 (8%)
Frame = +3
Query: 354 EGLKRESIFITTKLWNSYHEREQVIPALRKSLXKSQLGIRRPVFDSLAHSYV-*ERYLAR 530
+ + RE +F+T+KLWN+ H E V PALRK+L QL +++ + +
Sbjct: 68 KAVPREELFVTSKLWNTKHHPEDVEPALRKTLADLQLEYLDLYLMHWPYAFERGDNPFPK 127
Query: 531 HVD---------FLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGLEKPSALQIE 680
+ D + +TW+ + GL +++G+SNFN QI I+ +P+ LQ+E
Sbjct: 128 NADGTICYDSTHYKETWKALEALVAKGLVQALGLSNFNSRQIDDILSVASVRPAVLQVE 186
Score = 47.2 bits (107), Expect = 9e-05
Identities = 27/66 (40%), Positives = 38/66 (57%)
Frame = +2
Query: 152 LSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQVGR 331
L +G +P++ LGTW K + QV + AV YAL GY HID A YG E ++G
Sbjct: 8 LHTGQKMPLIGLGTW-----KSEPGQV----KAAVKYALSVGYRHIDCAAIYGNEPEIGE 58
Query: 332 ALXQEI 349
AL +++
Sbjct: 59 ALKEDV 64
Score = 35.9 bits (79), Expect = 0.23
Identities = 14/24 (58%), Positives = 17/24 (70%)
Frame = +1
Query: 448 LXNLNLEYVDLYLIHWPIAMFEND 519
L +L LEY+DLYL+HWP A D
Sbjct: 99 LADLQLEYLDLYLMHWPYAFERGD 122
>BC000670-1|AAH00670.1| 325|Homo sapiens aldo-keto reductase family
1, member A1 (aldehyde reductase) protein.
Length = 325
Score = 60.9 bits (141), Expect = 7e-09
Identities = 36/119 (30%), Positives = 61/119 (51%), Gaps = 10/119 (8%)
Frame = +3
Query: 354 EGLKRESIFITTKLWNSYHEREQVIPALRKSLXKSQLGIRRPVFDSLAHSYV-*ERYLAR 530
+ + RE +F+T+KLWN+ H E V PALRK+L QL +++ + +
Sbjct: 68 KAVPREELFVTSKLWNTKHHPEDVEPALRKTLADLQLEYLDLYLMHWPYAFERGDNPFPK 127
Query: 531 HVD---------FLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGLEKPSALQIE 680
+ D + +TW+ + GL +++G+SNFN QI I+ +P+ LQ+E
Sbjct: 128 NADGTICYDSTHYKETWKALEALVAKGLVQALGLSNFNSRQIDDILSVASVRPAVLQVE 186
Score = 47.2 bits (107), Expect = 9e-05
Identities = 27/66 (40%), Positives = 38/66 (57%)
Frame = +2
Query: 152 LSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQVGR 331
L +G +P++ LGTW K + QV + AV YAL GY HID A YG E ++G
Sbjct: 8 LHTGQKMPLIGLGTW-----KSEPGQV----KAAVKYALSVGYRHIDCAAIYGNEPEIGE 58
Query: 332 ALXQEI 349
AL +++
Sbjct: 59 ALKEDV 64
Score = 35.9 bits (79), Expect = 0.23
Identities = 14/24 (58%), Positives = 17/24 (70%)
Frame = +1
Query: 448 LXNLNLEYVDLYLIHWPIAMFEND 519
L +L LEY+DLYL+HWP A D
Sbjct: 99 LADLQLEYLDLYLMHWPYAFERGD 122
>AL355480-3|CAI22459.1| 325|Homo sapiens aldo-keto reductase family
1, member A1 (aldehydetase, 1 protein.
Length = 325
Score = 60.9 bits (141), Expect = 7e-09
Identities = 36/119 (30%), Positives = 61/119 (51%), Gaps = 10/119 (8%)
Frame = +3
Query: 354 EGLKRESIFITTKLWNSYHEREQVIPALRKSLXKSQLGIRRPVFDSLAHSYV-*ERYLAR 530
+ + RE +F+T+KLWN+ H E V PALRK+L QL +++ + +
Sbjct: 68 KAVPREELFVTSKLWNTKHHPEDVEPALRKTLADLQLEYLDLYLMHWPYAFERGDNPFPK 127
Query: 531 HVD---------FLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGLEKPSALQIE 680
+ D + +TW+ + GL +++G+SNFN QI I+ +P+ LQ+E
Sbjct: 128 NADGTICYDSTHYKETWKALEALVAKGLVQALGLSNFNSRQIDDILSVASVRPAVLQVE 186
Score = 47.2 bits (107), Expect = 9e-05
Identities = 27/66 (40%), Positives = 38/66 (57%)
Frame = +2
Query: 152 LSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQVGR 331
L +G +P++ LGTW K + QV + AV YAL GY HID A YG E ++G
Sbjct: 8 LHTGQKMPLIGLGTW-----KSEPGQV----KAAVKYALSVGYRHIDCAAIYGNEPEIGE 58
Query: 332 ALXQEI 349
AL +++
Sbjct: 59 ALKEDV 64
Score = 35.9 bits (79), Expect = 0.23
Identities = 14/24 (58%), Positives = 17/24 (70%)
Frame = +1
Query: 448 LXNLNLEYVDLYLIHWPIAMFEND 519
L +L LEY+DLYL+HWP A D
Sbjct: 99 LADLQLEYLDLYLMHWPYAFERGD 122
>AL355303-2|CAI14202.1| 323|Homo sapiens aldo-keto reductase family
1, member C4 (chlordecone reductase; 3-alpha hydroxy
protein.
Length = 323
Score = 60.9 bits (141), Expect = 7e-09
Identities = 45/125 (36%), Positives = 67/125 (53%), Gaps = 13/125 (10%)
Frame = +3
Query: 345 KFSEG-LKRESIFITTKLWNSYHEREQVIPALRKSLXKSQLG------IRRPVFDSLAHS 503
K ++G +KRE IF T+KLW ++ + + V PAL SL K QL + P+ +
Sbjct: 68 KIADGSVKREDIFYTSKLWCTFFQPQMVQPALESSLKKLQLDYVDLYLLHFPMALKPGET 127
Query: 504 YV*E----RYLARHVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDS-GLE-KPS 665
+ + + + VD TW M K GL KSIG+SNFN Q++ I++ GL+ KP
Sbjct: 128 PLPKDENGKVIFDTVDLSATWEVMEKCKDAGLAKSIGVSNFNCRQLEMILNKPGLKYKPV 187
Query: 666 ALQIE 680
Q+E
Sbjct: 188 CNQVE 192
Score = 47.6 bits (108), Expect = 7e-05
Identities = 28/76 (36%), Positives = 44/76 (57%), Gaps = 1/76 (1%)
Frame = +2
Query: 146 LQLSSGGNIPVVALGTWLGHR-PKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQ 322
++L+ G +PV+ GT+ P+ + V+VT A+EAG+ HID+AY Y E+Q
Sbjct: 8 VELNDGHFMPVLGFGTYAPPEVPRNRAVEVTK-------LAIEAGFRHIDSAYLYNNEEQ 60
Query: 323 VGRALXQEILRRT*KR 370
VG A+ +I + KR
Sbjct: 61 VGLAIRSKIADGSVKR 76
Score = 35.1 bits (77), Expect = 0.40
Identities = 15/29 (51%), Positives = 21/29 (72%)
Frame = +1
Query: 442 SPLXNLNLEYVDLYLIHWPIAMFENDTLL 528
S L L L+YVDLYL+H+P+A+ +T L
Sbjct: 101 SSLKKLQLDYVDLYLLHFPMALKPGETPL 129
>AF112485-1|AAF01260.1| 325|Homo sapiens aldehyde reductase
protein.
Length = 325
Score = 60.9 bits (141), Expect = 7e-09
Identities = 36/119 (30%), Positives = 61/119 (51%), Gaps = 10/119 (8%)
Frame = +3
Query: 354 EGLKRESIFITTKLWNSYHEREQVIPALRKSLXKSQLGIRRPVFDSLAHSYV-*ERYLAR 530
+ + RE +F+T+KLWN+ H E V PALRK+L QL +++ + +
Sbjct: 68 KAVPREELFVTSKLWNTKHHPEDVEPALRKTLADLQLEYLDLYLMHWPYAFERGDNPFPK 127
Query: 531 HVD---------FLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGLEKPSALQIE 680
+ D + +TW+ + GL +++G+SNFN QI I+ +P+ LQ+E
Sbjct: 128 NADGTICYDSTHYKETWKALEALVAKGLVQALGLSNFNSRQIDDILSVASVRPAVLQVE 186
Score = 47.2 bits (107), Expect = 9e-05
Identities = 27/66 (40%), Positives = 38/66 (57%)
Frame = +2
Query: 152 LSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQVGR 331
L +G +P++ LGTW K + QV + AV YAL GY HID A YG E ++G
Sbjct: 8 LHTGQKMPLIGLGTW-----KSEPGQV----KAAVKYALSVGYRHIDCAAIYGNEPEIGE 58
Query: 332 ALXQEI 349
AL +++
Sbjct: 59 ALKEDV 64
Score = 35.9 bits (79), Expect = 0.23
Identities = 14/24 (58%), Positives = 17/24 (70%)
Frame = +1
Query: 448 LXNLNLEYVDLYLIHWPIAMFEND 519
L +L LEY+DLYL+HWP A D
Sbjct: 99 LADLQLEYLDLYLMHWPYAFERGD 122
>AF036683-1|AAB92369.1| 325|Homo sapiens aldehyde reductase
protein.
Length = 325
Score = 60.9 bits (141), Expect = 7e-09
Identities = 36/119 (30%), Positives = 61/119 (51%), Gaps = 10/119 (8%)
Frame = +3
Query: 354 EGLKRESIFITTKLWNSYHEREQVIPALRKSLXKSQLGIRRPVFDSLAHSYV-*ERYLAR 530
+ + RE +F+T+KLWN+ H E V PALRK+L QL +++ + +
Sbjct: 68 KAVPREELFVTSKLWNTKHHPEDVEPALRKTLADLQLEYLDLYLMHWPYAFERGDNPFPK 127
Query: 531 HVD---------FLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGLEKPSALQIE 680
+ D + +TW+ + GL +++G+SNFN QI I+ +P+ LQ+E
Sbjct: 128 NADGTICYDSTHYKETWKALEALVAKGLVQALGLSNFNSRQIDDILSVASVRPAVLQVE 186
Score = 47.2 bits (107), Expect = 9e-05
Identities = 27/66 (40%), Positives = 38/66 (57%)
Frame = +2
Query: 152 LSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQVGR 331
L +G +P++ LGTW K + QV + AV YAL GY HID A YG E ++G
Sbjct: 8 LHTGQKMPLIGLGTW-----KSEPGQV----KAAVKYALSVGYRHIDCAAIYGNEPEIGE 58
Query: 332 ALXQEI 349
AL +++
Sbjct: 59 ALKEDV 64
Score = 35.9 bits (79), Expect = 0.23
Identities = 14/24 (58%), Positives = 17/24 (70%)
Frame = +1
Query: 448 LXNLNLEYVDLYLIHWPIAMFEND 519
L +L LEY+DLYL+HWP A D
Sbjct: 99 LADLQLEYLDLYLMHWPYAFERGD 122
>AB032163-1|BAA92893.1| 323|Homo sapiens dihydrodiol dehydrogenase
4 protein.
Length = 323
Score = 60.9 bits (141), Expect = 7e-09
Identities = 45/125 (36%), Positives = 67/125 (53%), Gaps = 13/125 (10%)
Frame = +3
Query: 345 KFSEG-LKRESIFITTKLWNSYHEREQVIPALRKSLXKSQLG------IRRPVFDSLAHS 503
K ++G +KRE IF T+KLW ++ + + V PAL SL K QL + P+ +
Sbjct: 68 KIADGSVKREDIFYTSKLWCTFFQPQMVQPALESSLKKLQLDYVDLYLLHFPMALKPGET 127
Query: 504 YV*E----RYLARHVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDS-GLE-KPS 665
+ + + + VD TW M K GL KSIG+SNFN Q++ I++ GL+ KP
Sbjct: 128 PLPKDENGKVIFDTVDLSATWEVMEKCKDAGLAKSIGVSNFNCRQLEMILNKPGLKYKPV 187
Query: 666 ALQIE 680
Q+E
Sbjct: 188 CNQVE 192
Score = 47.6 bits (108), Expect = 7e-05
Identities = 28/76 (36%), Positives = 44/76 (57%), Gaps = 1/76 (1%)
Frame = +2
Query: 146 LQLSSGGNIPVVALGTWLGHR-PKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQ 322
++L+ G +PV+ GT+ P+ + V+VT A+EAG+ HID+AY Y E+Q
Sbjct: 8 VELNDGHFMPVLGFGTYAPPEVPRNRAVEVTK-------LAIEAGFRHIDSAYLYNNEEQ 60
Query: 323 VGRALXQEILRRT*KR 370
VG A+ +I + KR
Sbjct: 61 VGLAIRSKIADGSVKR 76
Score = 35.1 bits (77), Expect = 0.40
Identities = 15/29 (51%), Positives = 21/29 (72%)
Frame = +1
Query: 442 SPLXNLNLEYVDLYLIHWPIAMFENDTLL 528
S L L L+YVDLYL+H+P+A+ +T L
Sbjct: 101 SSLKKLQLDYVDLYLLHFPMALKPGETPL 129
>AB031085-1|BAA92885.1| 323|Homo sapiens dihydrodiol dehydrogenase
4 protein.
Length = 323
Score = 60.9 bits (141), Expect = 7e-09
Identities = 45/125 (36%), Positives = 67/125 (53%), Gaps = 13/125 (10%)
Frame = +3
Query: 345 KFSEG-LKRESIFITTKLWNSYHEREQVIPALRKSLXKSQLG------IRRPVFDSLAHS 503
K ++G +KRE IF T+KLW ++ + + V PAL SL K QL + P+ +
Sbjct: 68 KIADGSVKREDIFYTSKLWCTFFQPQMVQPALESSLKKLQLDYVDLYLLHFPMALKPGET 127
Query: 504 YV*E----RYLARHVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDS-GLE-KPS 665
+ + + + VD TW M K GL KSIG+SNFN Q++ I++ GL+ KP
Sbjct: 128 PLPKDENGKVIFDTVDLSATWEVMEKCKDAGLAKSIGVSNFNCRQLEMILNKPGLKYKPV 187
Query: 666 ALQIE 680
Q+E
Sbjct: 188 CNQVE 192
Score = 47.6 bits (108), Expect = 7e-05
Identities = 28/76 (36%), Positives = 44/76 (57%), Gaps = 1/76 (1%)
Frame = +2
Query: 146 LQLSSGGNIPVVALGTWLGHR-PKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQ 322
++L+ G +PV+ GT+ P+ + V+VT A+EAG+ HID+AY Y E+Q
Sbjct: 8 VELNDGHFMPVLGFGTYAPPEVPRNRAVEVTK-------LAIEAGFRHIDSAYLYNNEEQ 60
Query: 323 VGRALXQEILRRT*KR 370
VG A+ +I + KR
Sbjct: 61 VGLAIRSKIADGSVKR 76
Score = 35.1 bits (77), Expect = 0.40
Identities = 15/29 (51%), Positives = 21/29 (72%)
Frame = +1
Query: 442 SPLXNLNLEYVDLYLIHWPIAMFENDTLL 528
S L L L+YVDLYL+H+P+A+ +T L
Sbjct: 101 SSLKKLQLDYVDLYLLHFPMALKPGETPL 129
>S68290-1|AAD14012.1| 320|Homo sapiens chlordecone reductase
homolog protein.
Length = 320
Score = 58.8 bits (136), Expect = 3e-08
Identities = 45/125 (36%), Positives = 63/125 (50%), Gaps = 13/125 (10%)
Frame = +3
Query: 345 KFSEG-LKRESIFITTKLWNSYHEREQVIPALRKSLXKSQLG------IRRPVFDSLAHS 503
K ++G +KRE IF T+KLW + H E PAL +SL QL I PV
Sbjct: 65 KIADGSVKREDIFYTSKLWCNSHRPELDRPALERSLKNLQLDYVDLYLIHFPVSVKPGEE 124
Query: 504 YV*E----RYLARHVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDS-GLE-KPS 665
+ + + L VD TW + K L KSIG+SNFN+ ++ I++ GL+ KP
Sbjct: 125 VIPKDENGKILFDTVDLCATWEAVEKCKDAELAKSIGVSNFNRSTLEMILNKPGLQVKPV 184
Query: 666 ALQIE 680
Q+E
Sbjct: 185 CNQVE 189
Score = 45.2 bits (102), Expect = 4e-04
Identities = 27/76 (35%), Positives = 43/76 (56%), Gaps = 1/76 (1%)
Frame = +2
Query: 146 LQLSSGGNIPVVALGTWL-GHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQ 322
++L+ G +PV+ GT+ PK K ++ T A+EAG+ HID+A+ Y E+Q
Sbjct: 5 VKLNDGHFMPVLGFGTYAPAEVPKSKALEATK-------LAIEAGFRHIDSAHLYNNEEQ 57
Query: 323 VGRALXQEILRRT*KR 370
VG A+ +I + KR
Sbjct: 58 VGLAIRSKIADGSVKR 73
>CR542203-1|CAG47000.1| 316|Homo sapiens AKR1B1 protein.
Length = 316
Score = 58.8 bits (136), Expect = 3e-08
Identities = 43/119 (36%), Positives = 64/119 (53%), Gaps = 12/119 (10%)
Frame = +3
Query: 360 LKRESIFITTKLWNSYHEREQVIPALRKSLXKSQLG------IRRPV-FDSLAHSYV*ER 518
+KRE +FI +KLW +YHE+ V A +K+L +L I P+ F + +
Sbjct: 68 VKREELFIVSKLWCTYHEKGLVKGACQKTLSDLKLDYLDLYLIHWPIGFKPGKEFFPLDE 127
Query: 519 ---YLARHVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDS-GLE-KPSALQIE 680
+ + LDTW M + GL K+IGISNFN Q++ I++ GL+ KP+ QIE
Sbjct: 128 SGNVVPSDTNILDTWAAMEELVDEGLVKAIGISNFNHLQVEMILNKPGLKYKPAVNQIE 186
Score = 49.2 bits (112), Expect = 2e-05
Identities = 28/79 (35%), Positives = 46/79 (58%)
Frame = +2
Query: 146 LQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQV 325
L L++G +P++ LGTW P G+V + AV A++ GY HID A+ Y E++V
Sbjct: 5 LLLNNGAKMPILGLGTWKS--PPGQVTE-------AVKVAIDVGYRHIDCAHVYQNENEV 55
Query: 326 GRALXQEILRRT*KRIYLY 382
G A+ +++ + KR L+
Sbjct: 56 GVAIQEKLREQVVKREELF 74
Score = 35.1 bits (77), Expect = 0.40
Identities = 13/18 (72%), Positives = 16/18 (88%)
Frame = +1
Query: 448 LXNLNLEYVDLYLIHWPI 501
L +L L+Y+DLYLIHWPI
Sbjct: 97 LSDLKLDYLDLYLIHWPI 114
>X15414-1|CAA33460.1| 316|Homo sapiens protein ( Human mRNA for
aldose reductase (EC 1.1.1.2). ).
Length = 316
Score = 57.6 bits (133), Expect = 7e-08
Identities = 43/119 (36%), Positives = 63/119 (52%), Gaps = 12/119 (10%)
Frame = +3
Query: 360 LKRESIFITTKLWNSYHEREQVIPALRKSLXKSQLG------IRRPV-FDSLAHSYV*ER 518
+KRE +FI +KLW +YHE+ V A +K+L +L I P F + +
Sbjct: 68 VKREELFIVSKLWCTYHEKGLVKGACQKTLSDLKLDYLDLYLIHWPTGFKPGKEFFPLDE 127
Query: 519 ---YLARHVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDS-GLE-KPSALQIE 680
+ + LDTW M + GL K+IGISNFN Q++ I++ GL+ KP+ QIE
Sbjct: 128 SGNVVPSDTNILDTWAAMEELVDEGLVKAIGISNFNHLQVEMILNKPGLKYKPAVNQIE 186
Score = 49.2 bits (112), Expect = 2e-05
Identities = 28/79 (35%), Positives = 46/79 (58%)
Frame = +2
Query: 146 LQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQV 325
L L++G +P++ LGTW P G+V + AV A++ GY HID A+ Y E++V
Sbjct: 5 LLLNNGAKMPILGLGTWKS--PPGQVTE-------AVKVAIDVGYRHIDCAHVYQNENEV 55
Query: 326 GRALXQEILRRT*KRIYLY 382
G A+ +++ + KR L+
Sbjct: 56 GVAIQEKLREQVVKREELF 74
Score = 33.5 bits (73), Expect = 1.2
Identities = 12/17 (70%), Positives = 15/17 (88%)
Frame = +1
Query: 448 LXNLNLEYVDLYLIHWP 498
L +L L+Y+DLYLIHWP
Sbjct: 97 LSDLKLDYLDLYLIHWP 113
>M59783-1|AAA51712.1| 316|Homo sapiens aldose reductase protein.
Length = 316
Score = 57.6 bits (133), Expect = 7e-08
Identities = 43/119 (36%), Positives = 63/119 (52%), Gaps = 12/119 (10%)
Frame = +3
Query: 360 LKRESIFITTKLWNSYHEREQVIPALRKSLXKSQLG------IRRPV-FDSLAHSYV*ER 518
+KRE +FI +KLW +YHE+ V A +K+L +L I P F + +
Sbjct: 68 VKREELFIVSKLWCTYHEKGLVKGACQKTLSDLKLDYLDLYLIHWPTGFKPGKEFFPLDE 127
Query: 519 ---YLARHVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDS-GLE-KPSALQIE 680
+ + LDTW M + GL K+IGISNFN Q++ I++ GL+ KP+ QIE
Sbjct: 128 SGNVVPSDTNILDTWAAMEELVDEGLVKAIGISNFNHLQVEMILNKPGLKYKPAVNQIE 186
Score = 49.2 bits (112), Expect = 2e-05
Identities = 28/79 (35%), Positives = 46/79 (58%)
Frame = +2
Query: 146 LQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQV 325
L L++G +P++ LGTW P G+V + AV A++ GY HID A+ Y E++V
Sbjct: 5 LLLNNGAKMPILGLGTWKS--PPGQVTE-------AVKVAIDVGYRHIDCAHVYQNENEV 55
Query: 326 GRALXQEILRRT*KRIYLY 382
G A+ +++ + KR L+
Sbjct: 56 GVAIQEKLREQVVKREELF 74
Score = 33.5 bits (73), Expect = 1.2
Identities = 12/17 (70%), Positives = 15/17 (88%)
Frame = +1
Query: 448 LXNLNLEYVDLYLIHWP 498
L +L L+Y+DLYLIHWP
Sbjct: 97 LSDLKLDYLDLYLIHWP 113
>M34720-1|AAA35560.1| 316|Homo sapiens protein ( Human aldose
reductase mRNA, complete cds. ).
Length = 316
Score = 57.6 bits (133), Expect = 7e-08
Identities = 43/119 (36%), Positives = 63/119 (52%), Gaps = 12/119 (10%)
Frame = +3
Query: 360 LKRESIFITTKLWNSYHEREQVIPALRKSLXKSQLG------IRRPV-FDSLAHSYV*ER 518
+KRE +FI +KLW +YHE+ V A +K+L +L I P F + +
Sbjct: 68 VKREELFIVSKLWCTYHEKGLVKGACQKTLSDLKLDYLDLYLIHWPTGFKPGKEFFPLDE 127
Query: 519 ---YLARHVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDS-GLE-KPSALQIE 680
+ + LDTW M + GL K+IGISNFN Q++ I++ GL+ KP+ QIE
Sbjct: 128 SGNVVPSDTNILDTWAAMEELVDEGLVKAIGISNFNHLQVEMILNKPGLKYKPAVNQIE 186
Score = 49.2 bits (112), Expect = 2e-05
Identities = 28/79 (35%), Positives = 46/79 (58%)
Frame = +2
Query: 146 LQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQV 325
L L++G +P++ LGTW P G+V + AV A++ GY HID A+ Y E++V
Sbjct: 5 LLLNNGAKMPILGLGTWKS--PPGQVTE-------AVKVAIDVGYRHIDCAHVYQNENEV 55
Query: 326 GRALXQEILRRT*KRIYLY 382
G A+ +++ + KR L+
Sbjct: 56 GVAIQEKLREQVVKREELF 74
Score = 33.5 bits (73), Expect = 1.2
Identities = 12/17 (70%), Positives = 15/17 (88%)
Frame = +1
Query: 448 LXNLNLEYVDLYLIHWP 498
L +L L+Y+DLYLIHWP
Sbjct: 97 LSDLKLDYLDLYLIHWP 113
>J05474-1|AAA51715.1| 316|Homo sapiens aldose reductase protein.
Length = 316
Score = 57.6 bits (133), Expect = 7e-08
Identities = 43/119 (36%), Positives = 63/119 (52%), Gaps = 12/119 (10%)
Frame = +3
Query: 360 LKRESIFITTKLWNSYHEREQVIPALRKSLXKSQLG------IRRPV-FDSLAHSYV*ER 518
+KRE +FI +KLW +YHE+ V A +K+L +L I P F + +
Sbjct: 68 VKREELFIVSKLWCTYHEKGLVKGACQKTLSDLKLDYLDLYLIHWPTGFKPGKEFFPLDE 127
Query: 519 ---YLARHVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDS-GLE-KPSALQIE 680
+ + LDTW M + GL K+IGISNFN Q++ I++ GL+ KP+ QIE
Sbjct: 128 SGNVVPSDTNILDTWAAMEELVDEGLVKAIGISNFNHLQVEMILNKPGLKYKPAVNQIE 186
Score = 49.2 bits (112), Expect = 2e-05
Identities = 28/79 (35%), Positives = 46/79 (58%)
Frame = +2
Query: 146 LQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQV 325
L L++G +P++ LGTW P G+V + AV A++ GY HID A+ Y E++V
Sbjct: 5 LLLNNGAKMPILGLGTWKS--PPGQVTE-------AVKVAIDVGYRHIDCAHVYQNENEV 55
Query: 326 GRALXQEILRRT*KRIYLY 382
G A+ +++ + KR L+
Sbjct: 56 GVAIQEKLREQVVKREELF 74
Score = 33.5 bits (73), Expect = 1.2
Identities = 12/17 (70%), Positives = 15/17 (88%)
Frame = +1
Query: 448 LXNLNLEYVDLYLIHWP 498
L +L L+Y+DLYLIHWP
Sbjct: 97 LSDLKLDYLDLYLIHWP 113
>J05017-1|AAA51714.1| 316|Homo sapiens ALDR1 protein.
Length = 316
Score = 57.6 bits (133), Expect = 7e-08
Identities = 43/119 (36%), Positives = 63/119 (52%), Gaps = 12/119 (10%)
Frame = +3
Query: 360 LKRESIFITTKLWNSYHEREQVIPALRKSLXKSQLG------IRRPV-FDSLAHSYV*ER 518
+KRE +FI +KLW +YHE+ V A +K+L +L I P F + +
Sbjct: 68 VKREELFIVSKLWCTYHEKGLVKGACQKTLSDLKLDYLDLYLIHWPTGFKPGKEFFPLDE 127
Query: 519 ---YLARHVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDS-GLE-KPSALQIE 680
+ + LDTW M + GL K+IGISNFN Q++ I++ GL+ KP+ QIE
Sbjct: 128 SGNVVPSDTNILDTWAAMEELVDEGLVKAIGISNFNHLQVEMILNKPGLKYKPAVNQIE 186
Score = 48.4 bits (110), Expect = 4e-05
Identities = 27/77 (35%), Positives = 45/77 (58%)
Frame = +2
Query: 152 LSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQVGR 331
L++G +P++ LGTW P G+V + AV A++ GY HID A+ Y E++VG
Sbjct: 7 LNNGAKMPILGLGTWKS--PPGQVTE-------AVKVAIDVGYRHIDCAHVYQNENEVGV 57
Query: 332 ALXQEILRRT*KRIYLY 382
A+ +++ + KR L+
Sbjct: 58 AIQEKLREQVVKREELF 74
Score = 33.5 bits (73), Expect = 1.2
Identities = 12/17 (70%), Positives = 15/17 (88%)
Frame = +1
Query: 448 LXNLNLEYVDLYLIHWP 498
L +L L+Y+DLYLIHWP
Sbjct: 97 LSDLKLDYLDLYLIHWP 113
>J04795-1|AAA51713.1| 316|Homo sapiens ALDR1 protein.
Length = 316
Score = 57.6 bits (133), Expect = 7e-08
Identities = 43/119 (36%), Positives = 63/119 (52%), Gaps = 12/119 (10%)
Frame = +3
Query: 360 LKRESIFITTKLWNSYHEREQVIPALRKSLXKSQLG------IRRPV-FDSLAHSYV*ER 518
+KRE +FI +KLW +YHE+ V A +K+L +L I P F + +
Sbjct: 68 VKREELFIVSKLWCTYHEKGLVKGACQKTLSDLKLDYLDLYLIHWPTGFKPGKEFFPLDE 127
Query: 519 ---YLARHVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDS-GLE-KPSALQIE 680
+ + LDTW M + GL K+IGISNFN Q++ I++ GL+ KP+ QIE
Sbjct: 128 SGNVVPSDTNILDTWAAMEELVDEGLVKAIGISNFNHLQVEMILNKPGLKYKPAVNQIE 186
Score = 49.2 bits (112), Expect = 2e-05
Identities = 28/79 (35%), Positives = 46/79 (58%)
Frame = +2
Query: 146 LQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQV 325
L L++G +P++ LGTW P G+V + AV A++ GY HID A+ Y E++V
Sbjct: 5 LLLNNGAKMPILGLGTWKS--PPGQVTE-------AVKVAIDVGYRHIDCAHVYQNENEV 55
Query: 326 GRALXQEILRRT*KRIYLY 382
G A+ +++ + KR L+
Sbjct: 56 GVAIQEKLREQVVKREELF 74
Score = 33.5 bits (73), Expect = 1.2
Identities = 12/17 (70%), Positives = 15/17 (88%)
Frame = +1
Query: 448 LXNLNLEYVDLYLIHWP 498
L +L L+Y+DLYLIHWP
Sbjct: 97 LSDLKLDYLDLYLIHWP 113
>BT019859-1|AAV38662.1| 316|Homo sapiens aldo-keto reductase family
1, member B1 (aldose reductase) protein.
Length = 316
Score = 57.6 bits (133), Expect = 7e-08
Identities = 43/119 (36%), Positives = 63/119 (52%), Gaps = 12/119 (10%)
Frame = +3
Query: 360 LKRESIFITTKLWNSYHEREQVIPALRKSLXKSQLG------IRRPV-FDSLAHSYV*ER 518
+KRE +FI +KLW +YHE+ V A +K+L +L I P F + +
Sbjct: 68 VKREELFIVSKLWCTYHEKGLVKGACQKTLSDLKLDYLDLYLIHWPTGFKPGKEFFPLDE 127
Query: 519 ---YLARHVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDS-GLE-KPSALQIE 680
+ + LDTW M + GL K+IGISNFN Q++ I++ GL+ KP+ QIE
Sbjct: 128 SGNVVPSDTNILDTWAAMEELVDEGLVKAIGISNFNHLQVEMILNKPGLKYKPAVNQIE 186
Score = 49.2 bits (112), Expect = 2e-05
Identities = 28/79 (35%), Positives = 46/79 (58%)
Frame = +2
Query: 146 LQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQV 325
L L++G +P++ LGTW P G+V + AV A++ GY HID A+ Y E++V
Sbjct: 5 LLLNNGAKMPILGLGTWKS--PPGQVTE-------AVKVAIDVGYRHIDCAHVYQNENEV 55
Query: 326 GRALXQEILRRT*KRIYLY 382
G A+ +++ + KR L+
Sbjct: 56 GVAIQEKLREQVVKREELF 74
Score = 33.5 bits (73), Expect = 1.2
Identities = 12/17 (70%), Positives = 15/17 (88%)
Frame = +1
Query: 448 LXNLNLEYVDLYLIHWP 498
L +L L+Y+DLYLIHWP
Sbjct: 97 LSDLKLDYLDLYLIHWP 113
>BC010391-1|AAH10391.1| 316|Homo sapiens aldo-keto reductase family
1, member B1 (aldose reductase) protein.
Length = 316
Score = 57.6 bits (133), Expect = 7e-08
Identities = 43/119 (36%), Positives = 63/119 (52%), Gaps = 12/119 (10%)
Frame = +3
Query: 360 LKRESIFITTKLWNSYHEREQVIPALRKSLXKSQLG------IRRPV-FDSLAHSYV*ER 518
+KRE +FI +KLW +YHE+ V A +K+L +L I P F + +
Sbjct: 68 VKREELFIVSKLWCTYHEKGLVKGACQKTLSDLKLDYLDLYLIHWPTGFKPGKEFFPLDE 127
Query: 519 ---YLARHVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDS-GLE-KPSALQIE 680
+ + LDTW M + GL K+IGISNFN Q++ I++ GL+ KP+ QIE
Sbjct: 128 SGNVVPSDTNILDTWAAMEELVDEGLVKAIGISNFNHLQVEMILNKPGLKYKPAVNQIE 186
Score = 49.2 bits (112), Expect = 2e-05
Identities = 28/79 (35%), Positives = 46/79 (58%)
Frame = +2
Query: 146 LQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQV 325
L L++G +P++ LGTW P G+V + AV A++ GY HID A+ Y E++V
Sbjct: 5 LLLNNGAKMPILGLGTWKS--PPGQVTE-------AVKVAIDVGYRHIDCAHVYQNENEV 55
Query: 326 GRALXQEILRRT*KRIYLY 382
G A+ +++ + KR L+
Sbjct: 56 GVAIQEKLREQVVKREELF 74
Score = 33.5 bits (73), Expect = 1.2
Identities = 12/17 (70%), Positives = 15/17 (88%)
Frame = +1
Query: 448 LXNLNLEYVDLYLIHWP 498
L +L L+Y+DLYLIHWP
Sbjct: 97 LSDLKLDYLDLYLIHWP 113
>BC000260-1|AAH00260.1| 316|Homo sapiens aldo-keto reductase family
1, member B1 (aldose reductase) protein.
Length = 316
Score = 57.6 bits (133), Expect = 7e-08
Identities = 43/119 (36%), Positives = 63/119 (52%), Gaps = 12/119 (10%)
Frame = +3
Query: 360 LKRESIFITTKLWNSYHEREQVIPALRKSLXKSQLG------IRRPV-FDSLAHSYV*ER 518
+KRE +FI +KLW +YHE+ V A +K+L +L I P F + +
Sbjct: 68 VKREELFIVSKLWCTYHEKGLVKGACQKTLSDLKLDYLDLYLIHWPTGFKPGKEFFPLDE 127
Query: 519 ---YLARHVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDS-GLE-KPSALQIE 680
+ + LDTW M + GL K+IGISNFN Q++ I++ GL+ KP+ QIE
Sbjct: 128 SGNVVPSDTNILDTWAAMEELVDEGLVKAIGISNFNHLQVEMILNKPGLKYKPAVNQIE 186
Score = 49.2 bits (112), Expect = 2e-05
Identities = 28/79 (35%), Positives = 46/79 (58%)
Frame = +2
Query: 146 LQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQV 325
L L++G +P++ LGTW P G+V + AV A++ GY HID A+ Y E++V
Sbjct: 5 LLLNNGAKMPILGLGTWKS--PPGQVTE-------AVKVAIDVGYRHIDCAHVYQNENEV 55
Query: 326 GRALXQEILRRT*KRIYLY 382
G A+ +++ + KR L+
Sbjct: 56 GVAIQEKLREQVVKREELF 74
Score = 33.5 bits (73), Expect = 1.2
Identities = 12/17 (70%), Positives = 15/17 (88%)
Frame = +1
Query: 448 LXNLNLEYVDLYLIHWP 498
L +L L+Y+DLYLIHWP
Sbjct: 97 LSDLKLDYLDLYLIHWP 113
>AF328729-1|AAN09721.1| 316|Homo sapiens CTCL tumor antigen
HD-CL-07 protein.
Length = 316
Score = 57.6 bits (133), Expect = 7e-08
Identities = 43/119 (36%), Positives = 63/119 (52%), Gaps = 12/119 (10%)
Frame = +3
Query: 360 LKRESIFITTKLWNSYHEREQVIPALRKSLXKSQLG------IRRPV-FDSLAHSYV*ER 518
+KRE +FI +KLW +YHE+ V A +K+L +L I P F + +
Sbjct: 68 VKREELFIVSKLWCTYHEKGLVKGACQKTLSDLKLDYLDLYLIHWPTGFKPGKEFFPLDE 127
Query: 519 ---YLARHVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDS-GLE-KPSALQIE 680
+ + LDTW M + GL K+IGISNFN Q++ I++ GL+ KP+ QIE
Sbjct: 128 SGNVVPSDTNILDTWAAMEELVDEGLVKAIGISNFNHLQVEMILNKPGLKYKPAVNQIE 186
Score = 49.2 bits (112), Expect = 2e-05
Identities = 28/79 (35%), Positives = 46/79 (58%)
Frame = +2
Query: 146 LQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQV 325
L L++G +P++ LGTW P G+V + AV A++ GY HID A+ Y E++V
Sbjct: 5 LLLNNGAKMPILGLGTWKS--PPGQVTE-------AVKVAIDVGYRHIDCAHVYQNENEV 55
Query: 326 GRALXQEILRRT*KRIYLY 382
G A+ +++ + KR L+
Sbjct: 56 GVAIQEKLREQVVKREELF 74
Score = 33.5 bits (73), Expect = 1.2
Identities = 12/17 (70%), Positives = 15/17 (88%)
Frame = +1
Query: 448 LXNLNLEYVDLYLIHWP 498
L +L L+Y+DLYLIHWP
Sbjct: 97 LSDLKLDYLDLYLIHWP 113
>AF032455-1|AAB88851.1| 316|Homo sapiens aldose reductase protein.
Length = 316
Score = 57.6 bits (133), Expect = 7e-08
Identities = 43/119 (36%), Positives = 63/119 (52%), Gaps = 12/119 (10%)
Frame = +3
Query: 360 LKRESIFITTKLWNSYHEREQVIPALRKSLXKSQLG------IRRPV-FDSLAHSYV*ER 518
+KRE +FI +KLW +YHE+ V A +K+L +L I P F + +
Sbjct: 68 VKREELFIVSKLWCTYHEKGLVKGACQKTLSDLKLDYLDLYLIHWPTGFKPGKEFFPLDE 127
Query: 519 ---YLARHVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDS-GLE-KPSALQIE 680
+ + LDTW M + GL K+IGISNFN Q++ I++ GL+ KP+ QIE
Sbjct: 128 SGNVVPSDTNILDTWAAMEELVDEGLVKAIGISNFNHLQVEMILNKPGLKYKPAVNQIE 186
Score = 49.2 bits (112), Expect = 2e-05
Identities = 28/79 (35%), Positives = 46/79 (58%)
Frame = +2
Query: 146 LQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQV 325
L L++G +P++ LGTW P G+V + AV A++ GY HID A+ Y E++V
Sbjct: 5 LLLNNGAKMPILGLGTWKS--PPGQVTE-------AVKVAIDVGYRHIDCAHVYQNENEV 55
Query: 326 GRALXQEILRRT*KRIYLY 382
G A+ +++ + KR L+
Sbjct: 56 GVAIQEKLREQVVKREELF 74
Score = 33.5 bits (73), Expect = 1.2
Identities = 12/17 (70%), Positives = 15/17 (88%)
Frame = +1
Query: 448 LXNLNLEYVDLYLIHWP 498
L +L L+Y+DLYLIHWP
Sbjct: 97 LSDLKLDYLDLYLIHWP 113
>AB209796-1|BAD93033.1| 260|Homo sapiens aldo-keto reductase family
1, member B1 variant protein.
Length = 260
Score = 57.6 bits (133), Expect = 7e-08
Identities = 43/119 (36%), Positives = 63/119 (52%), Gaps = 12/119 (10%)
Frame = +3
Query: 360 LKRESIFITTKLWNSYHEREQVIPALRKSLXKSQLG------IRRPV-FDSLAHSYV*ER 518
+KRE +FI +KLW +YHE+ V A +K+L +L I P F + +
Sbjct: 65 VKREELFIVSKLWCTYHEKGLVKGACQKTLSDLKLDYLDLYLIHWPTGFKPGKEFFPLDE 124
Query: 519 ---YLARHVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDS-GLE-KPSALQIE 680
+ + LDTW M + GL K+IGISNFN Q++ I++ GL+ KP+ QIE
Sbjct: 125 SGNVVPSDTNILDTWAAMEELVDEGLVKAIGISNFNHLQVEMILNKPGLKYKPAVNQIE 183
Score = 49.2 bits (112), Expect = 2e-05
Identities = 28/79 (35%), Positives = 46/79 (58%)
Frame = +2
Query: 146 LQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQV 325
L L++G +P++ LGTW P G+V + AV A++ GY HID A+ Y E++V
Sbjct: 2 LLLNNGAKMPILGLGTWKS--PPGQVTE-------AVKVAIDVGYRHIDCAHVYQNENEV 52
Query: 326 GRALXQEILRRT*KRIYLY 382
G A+ +++ + KR L+
Sbjct: 53 GVAIQEKLREQVVKREELF 71
Score = 33.5 bits (73), Expect = 1.2
Identities = 12/17 (70%), Positives = 15/17 (88%)
Frame = +1
Query: 448 LXNLNLEYVDLYLIHWP 498
L +L L+Y+DLYLIHWP
Sbjct: 94 LSDLKLDYLDLYLIHWP 110
>Z28339-1|CAA82193.1| 326|Homo sapiens delta 4-3-oxosteroid 5
beta-reductase protein.
Length = 326
Score = 57.2 bits (132), Expect = 9e-08
Identities = 43/126 (34%), Positives = 65/126 (51%), Gaps = 13/126 (10%)
Frame = +3
Query: 342 KKFSEG-LKRESIFITTKLWNSYHEREQVIPALRKSLXKSQLG------IRRPVF----D 488
+K +EG ++RE IF KLW + H E V P L ++L QL I P+ D
Sbjct: 70 EKIAEGKVRREDIFYCGKLWATNHVPEMVRPTLERTLRVLQLDYVDLYIIEVPMAFKPGD 129
Query: 489 SLAHSYV*ERYLARHVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDS-GLE-KP 662
+ ++L + TW M K GL KS+G+SNFN+ Q++ I++ GL+ KP
Sbjct: 130 EIYPRDENGKWLYHKSNLCATWEAMEACKDAGLVKSLGVSNFNRRQLELILNKPGLKHKP 189
Query: 663 SALQIE 680
+ Q+E
Sbjct: 190 VSNQVE 195
Score = 45.2 bits (102), Expect = 4e-04
Identities = 25/68 (36%), Positives = 38/68 (55%)
Frame = +2
Query: 146 LQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQV 325
+ LS G +IP++ LGT+ + K T+ V A++ GY HID AY Y E +V
Sbjct: 10 IPLSDGNSIPIIGLGTYSEPKSTPKGACATS-----VKVAIDTGYRHIDGAYIYQNEHEV 64
Query: 326 GRALXQEI 349
G A+ ++I
Sbjct: 65 GEAIREKI 72
>BC130627-1|AAI30628.1| 326|Homo sapiens aldo-keto reductase family
1, member D1 (delta 4-3-ketosteroid-5-beta-reductase
protein.
Length = 326
Score = 57.2 bits (132), Expect = 9e-08
Identities = 43/126 (34%), Positives = 65/126 (51%), Gaps = 13/126 (10%)
Frame = +3
Query: 342 KKFSEG-LKRESIFITTKLWNSYHEREQVIPALRKSLXKSQLG------IRRPVF----D 488
+K +EG ++RE IF KLW + H E V P L ++L QL I P+ D
Sbjct: 70 EKIAEGKVRREDIFYCGKLWATNHVPEMVRPTLERTLRVLQLDYVDLYIIEVPMAFKPGD 129
Query: 489 SLAHSYV*ERYLARHVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDS-GLE-KP 662
+ ++L + TW M K GL KS+G+SNFN+ Q++ I++ GL+ KP
Sbjct: 130 EIYPRDENGKWLYHKSNLCATWEAMEACKDAGLVKSLGVSNFNRRQLELILNKPGLKHKP 189
Query: 663 SALQIE 680
+ Q+E
Sbjct: 190 VSNQVE 195
Score = 45.2 bits (102), Expect = 4e-04
Identities = 25/68 (36%), Positives = 38/68 (55%)
Frame = +2
Query: 146 LQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQV 325
+ LS G +IP++ LGT+ + K T+ V A++ GY HID AY Y E +V
Sbjct: 10 IPLSDGNSIPIIGLGTYSEPKSTPKGACATS-----VKVAIDTGYRHIDGAYIYQNEHEV 64
Query: 326 GRALXQEI 349
G A+ ++I
Sbjct: 65 GEAIREKI 72
>BC130625-1|AAI30626.1| 326|Homo sapiens aldo-keto reductase family
1, member D1 (delta 4-3-ketosteroid-5-beta-reductase
protein.
Length = 326
Score = 57.2 bits (132), Expect = 9e-08
Identities = 43/126 (34%), Positives = 65/126 (51%), Gaps = 13/126 (10%)
Frame = +3
Query: 342 KKFSEG-LKRESIFITTKLWNSYHEREQVIPALRKSLXKSQLG------IRRPVF----D 488
+K +EG ++RE IF KLW + H E V P L ++L QL I P+ D
Sbjct: 70 EKIAEGKVRREDIFYCGKLWATNHVPEMVRPTLERTLRVLQLDYVDLYIIEVPMAFKPGD 129
Query: 489 SLAHSYV*ERYLARHVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDS-GLE-KP 662
+ ++L + TW M K GL KS+G+SNFN+ Q++ I++ GL+ KP
Sbjct: 130 EIYPRDENGKWLYHKSNLCATWEAMEACKDAGLVKSLGVSNFNRRQLELILNKPGLKHKP 189
Query: 663 SALQIE 680
+ Q+E
Sbjct: 190 VSNQVE 195
Score = 45.2 bits (102), Expect = 4e-04
Identities = 25/68 (36%), Positives = 38/68 (55%)
Frame = +2
Query: 146 LQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQV 325
+ LS G +IP++ LGT+ + K T+ V A++ GY HID AY Y E +V
Sbjct: 10 IPLSDGNSIPIIGLGTYSEPKSTPKGACATS-----VKVAIDTGYRHIDGAYIYQNEHEV 64
Query: 326 GRALXQEI 349
G A+ ++I
Sbjct: 65 GEAIREKI 72
>AF283659-1|AAG39381.1| 326|Homo sapiens 5-beta steroid reductase
protein.
Length = 326
Score = 57.2 bits (132), Expect = 9e-08
Identities = 43/126 (34%), Positives = 65/126 (51%), Gaps = 13/126 (10%)
Frame = +3
Query: 342 KKFSEG-LKRESIFITTKLWNSYHEREQVIPALRKSLXKSQLG------IRRPVF----D 488
+K +EG ++RE IF KLW + H E V P L ++L QL I P+ D
Sbjct: 70 EKIAEGKVRREDIFYCGKLWATNHVPEMVRPTLERTLRVLQLDYVDLYIIEVPMAFKPGD 129
Query: 489 SLAHSYV*ERYLARHVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDS-GLE-KP 662
+ ++L + TW M K GL KS+G+SNFN+ Q++ I++ GL+ KP
Sbjct: 130 EIYPRDENGKWLYHKSNLCATWEAMEACKDAGLVKSLGVSNFNRRQLELILNKPGLKHKP 189
Query: 663 SALQIE 680
+ Q+E
Sbjct: 190 VSNQVE 195
Score = 45.2 bits (102), Expect = 4e-04
Identities = 25/68 (36%), Positives = 38/68 (55%)
Frame = +2
Query: 146 LQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQV 325
+ LS G +IP++ LGT+ + K T+ V A++ GY HID AY Y E +V
Sbjct: 10 IPLSDGNSIPIIGLGTYSEPKSTPKGACATS-----VKVAIDTGYRHIDGAYIYQNEHEV 64
Query: 326 GRALXQEI 349
G A+ ++I
Sbjct: 65 GEAIREKI 72
>CR450351-1|CAG29347.1| 316|Homo sapiens AKR1B1 protein.
Length = 316
Score = 56.8 bits (131), Expect = 1e-07
Identities = 43/119 (36%), Positives = 62/119 (52%), Gaps = 12/119 (10%)
Frame = +3
Query: 360 LKRESIFITTKLWNSYHEREQVIPALRKSLXKSQLG------IRRPV-FDSLAHSYV*ER 518
+KRE +FI +KLW +YHE+ V A +K+L +L I P F + +
Sbjct: 68 VKREELFIVSKLWCTYHEKGLVKGACQKTLSDLKLDYLDLYLIHWPTGFRPGKEFFPLDE 127
Query: 519 ---YLARHVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDS-GLE-KPSALQIE 680
+ + LDTW M + GL K+IGISNFN Q++ I+ GL+ KP+ QIE
Sbjct: 128 SGNVVPSDTNILDTWAAMEELVDEGLVKAIGISNFNHLQVEMILSKPGLKYKPAVNQIE 186
Score = 49.2 bits (112), Expect = 2e-05
Identities = 28/79 (35%), Positives = 46/79 (58%)
Frame = +2
Query: 146 LQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQV 325
L L++G +P++ LGTW P G+V + AV A++ GY HID A+ Y E++V
Sbjct: 5 LLLNNGAKMPILGLGTWKS--PPGQVTE-------AVKVAIDVGYRHIDCAHVYQNENEV 55
Query: 326 GRALXQEILRRT*KRIYLY 382
G A+ +++ + KR L+
Sbjct: 56 GVAIQEKLREQVVKREELF 74
Score = 33.5 bits (73), Expect = 1.2
Identities = 12/17 (70%), Positives = 15/17 (88%)
Frame = +1
Query: 448 LXNLNLEYVDLYLIHWP 498
L +L L+Y+DLYLIHWP
Sbjct: 97 LSDLKLDYLDLYLIHWP 113
>U37100-1|AAC17469.1| 316|Homo sapiens aldose reductase-like
peptide protein.
Length = 316
Score = 55.2 bits (127), Expect = 3e-07
Identities = 32/79 (40%), Positives = 47/79 (59%)
Frame = +2
Query: 146 LQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQV 325
++LS+ +P+V LGTW P GKV ++AV A++AGY HID AY Y E +V
Sbjct: 5 VELSTKAKMPIVGLGTWKS--PLGKV-------KEAVKVAIDAGYRHIDCAYVYQNEHEV 55
Query: 326 GRALXQEILRRT*KRIYLY 382
G A+ ++I + KR L+
Sbjct: 56 GEAIQEKIQEKAVKREDLF 74
Score = 52.4 bits (120), Expect = 2e-06
Identities = 39/121 (32%), Positives = 60/121 (49%), Gaps = 12/121 (9%)
Frame = +3
Query: 354 EGLKRESIFITTKLWNSYHEREQVIPALRKSLXKSQLG------IRRPVF----DSLAHS 503
+ +KRE +FI +KLW ++ ER V A K+L +L I P D L
Sbjct: 66 KAVKREDLFIVSKLWPTFFERPLVRKAFEKTLKDLKLSYLDVYLIHWPQGFKSGDDLFPK 125
Query: 504 YV*ERYLARHVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDS-GLE-KPSALQI 677
+ FLD W M + GL K++G+SNF+ QI+++++ GL+ KP Q+
Sbjct: 126 DDKGNAIGGKATFLDAWEAMEELVDEGLVKALGVSNFSHFQIEKLLNKPGLKYKPVTNQV 185
Query: 678 E 680
E
Sbjct: 186 E 186
Score = 32.7 bits (71), Expect = 2.1
Identities = 13/26 (50%), Positives = 16/26 (61%)
Frame = +1
Query: 448 LXNLNLEYVDLYLIHWPIAMFENDTL 525
L +L L Y+D+YLIHWP D L
Sbjct: 97 LKDLKLSYLDVYLIHWPQGFKSGDDL 122
>CR541801-1|CAG46600.1| 316|Homo sapiens AKR1B10 protein.
Length = 316
Score = 55.2 bits (127), Expect = 3e-07
Identities = 32/79 (40%), Positives = 47/79 (59%)
Frame = +2
Query: 146 LQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQV 325
++LS+ +P+V LGTW P GKV ++AV A++AGY HID AY Y E +V
Sbjct: 5 VELSTKAKMPIVGLGTWKS--PLGKV-------KEAVKVAIDAGYRHIDCAYVYQNEHEV 55
Query: 326 GRALXQEILRRT*KRIYLY 382
G A+ ++I + KR L+
Sbjct: 56 GEAIQEKIQEKAVKREDLF 74
Score = 52.4 bits (120), Expect = 2e-06
Identities = 39/121 (32%), Positives = 60/121 (49%), Gaps = 12/121 (9%)
Frame = +3
Query: 354 EGLKRESIFITTKLWNSYHEREQVIPALRKSLXKSQLG------IRRPVF----DSLAHS 503
+ +KRE +FI +KLW ++ ER V A K+L +L I P D L
Sbjct: 66 KAVKREDLFIVSKLWPTFFERPLVRKAFEKTLKDLKLSYLDVYLIHWPQGFKSGDDLFPK 125
Query: 504 YV*ERYLARHVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDS-GLE-KPSALQI 677
+ FLD W M + GL K++G+SNF+ QI+++++ GL+ KP Q+
Sbjct: 126 DDKGNAIGGKATFLDAWEAMEELVDEGLVKALGVSNFSHFQIEKLLNKPGLKYKPVTNQV 185
Query: 678 E 680
E
Sbjct: 186 E 186
Score = 32.7 bits (71), Expect = 2.1
Identities = 13/26 (50%), Positives = 16/26 (61%)
Frame = +1
Query: 448 LXNLNLEYVDLYLIHWPIAMFENDTL 525
L +L L Y+D+YLIHWP D L
Sbjct: 97 LKDLKLSYLDVYLIHWPQGFKSGDDL 122
>BT006794-1|AAP35440.1| 316|Homo sapiens aldo-keto reductase family
1, member B10 (aldose reductase) protein.
Length = 316
Score = 55.2 bits (127), Expect = 3e-07
Identities = 32/79 (40%), Positives = 47/79 (59%)
Frame = +2
Query: 146 LQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQV 325
++LS+ +P+V LGTW P GKV ++AV A++AGY HID AY Y E +V
Sbjct: 5 VELSTKAKMPIVGLGTWKS--PLGKV-------KEAVKVAIDAGYRHIDCAYVYQNEHEV 55
Query: 326 GRALXQEILRRT*KRIYLY 382
G A+ ++I + KR L+
Sbjct: 56 GEAIQEKIQEKAVKREDLF 74
Score = 52.4 bits (120), Expect = 2e-06
Identities = 39/121 (32%), Positives = 60/121 (49%), Gaps = 12/121 (9%)
Frame = +3
Query: 354 EGLKRESIFITTKLWNSYHEREQVIPALRKSLXKSQLG------IRRPVF----DSLAHS 503
+ +KRE +FI +KLW ++ ER V A K+L +L I P D L
Sbjct: 66 KAVKREDLFIVSKLWPTFFERPLVRKAFEKTLKDLKLSYLDVYLIHWPQGFKSGDDLFPK 125
Query: 504 YV*ERYLARHVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDS-GLE-KPSALQI 677
+ FLD W M + GL K++G+SNF+ QI+++++ GL+ KP Q+
Sbjct: 126 DDKGNAIGGKATFLDAWEAMEELVDEGLVKALGVSNFSHFQIEKLLNKPGLKYKPVTNQV 185
Query: 678 E 680
E
Sbjct: 186 E 186
Score = 32.7 bits (71), Expect = 2.1
Identities = 13/26 (50%), Positives = 16/26 (61%)
Frame = +1
Query: 448 LXNLNLEYVDLYLIHWPIAMFENDTL 525
L +L L Y+D+YLIHWP D L
Sbjct: 97 LKDLKLSYLDVYLIHWPQGFKSGDDL 122
>BC008837-1|AAH08837.1| 316|Homo sapiens aldo-keto reductase family
1, member B10 (aldose reductase) protein.
Length = 316
Score = 55.2 bits (127), Expect = 3e-07
Identities = 32/79 (40%), Positives = 47/79 (59%)
Frame = +2
Query: 146 LQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQV 325
++LS+ +P+V LGTW P GKV ++AV A++AGY HID AY Y E +V
Sbjct: 5 VELSTKAKMPIVGLGTWKS--PLGKV-------KEAVKVAIDAGYRHIDCAYVYQNEHEV 55
Query: 326 GRALXQEILRRT*KRIYLY 382
G A+ ++I + KR L+
Sbjct: 56 GEAIQEKIQEKAVKREDLF 74
Score = 52.4 bits (120), Expect = 2e-06
Identities = 39/121 (32%), Positives = 60/121 (49%), Gaps = 12/121 (9%)
Frame = +3
Query: 354 EGLKRESIFITTKLWNSYHEREQVIPALRKSLXKSQLG------IRRPVF----DSLAHS 503
+ +KRE +FI +KLW ++ ER V A K+L +L I P D L
Sbjct: 66 KAVKREDLFIVSKLWPTFFERPLVRKAFEKTLKDLKLSYLDVYLIHWPQGFKSGDDLFPK 125
Query: 504 YV*ERYLARHVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDS-GLE-KPSALQI 677
+ FLD W M + GL K++G+SNF+ QI+++++ GL+ KP Q+
Sbjct: 126 DDKGNAIGGKATFLDAWEAMEELVDEGLVKALGVSNFSHFQIEKLLNKPGLKYKPVTNQV 185
Query: 678 E 680
E
Sbjct: 186 E 186
Score = 32.7 bits (71), Expect = 2.1
Identities = 13/26 (50%), Positives = 16/26 (61%)
Frame = +1
Query: 448 LXNLNLEYVDLYLIHWPIAMFENDTL 525
L +L L Y+D+YLIHWP D L
Sbjct: 97 LKDLKLSYLDVYLIHWPQGFKSGDDL 122
>AF524864-1|AAO13380.1| 316|Homo sapiens aldo-ketoreductase
protein.
Length = 316
Score = 55.2 bits (127), Expect = 3e-07
Identities = 32/79 (40%), Positives = 47/79 (59%)
Frame = +2
Query: 146 LQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQV 325
++LS+ +P+V LGTW P GKV ++AV A++AGY HID AY Y E +V
Sbjct: 5 VELSTKAKMPIVGLGTWKS--PLGKV-------KEAVKVAIDAGYRHIDCAYVYQNEHEV 55
Query: 326 GRALXQEILRRT*KRIYLY 382
G A+ ++I + KR L+
Sbjct: 56 GEAIQEKIQEKAVKREDLF 74
Score = 52.8 bits (121), Expect = 2e-06
Identities = 39/121 (32%), Positives = 60/121 (49%), Gaps = 12/121 (9%)
Frame = +3
Query: 354 EGLKRESIFITTKLWNSYHEREQVIPALRKSLXKSQLG------IRRPVF----DSLAHS 503
+ +KRE +FI +KLW ++ ER V A K+L +L I P D L
Sbjct: 66 KAVKREDLFIASKLWPTFFERPLVRKAFEKTLKDPKLSYLDVYLIHWPQGFKSGDDLFPK 125
Query: 504 YV*ERYLARHVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDS-GLE-KPSALQI 677
+ FLD W M + GL K++G+SNF+ QI+++++ GL+ KP Q+
Sbjct: 126 DDKGNAIGGKATFLDAWEAMEELVDEGLVKALGVSNFSHFQIEKLLNKPGLKYKPVTNQV 185
Query: 678 E 680
E
Sbjct: 186 E 186
>AF052577-1|AAC36465.1| 316|Homo sapiens aldo-keto reductase
protein.
Length = 316
Score = 55.2 bits (127), Expect = 3e-07
Identities = 32/79 (40%), Positives = 47/79 (59%)
Frame = +2
Query: 146 LQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQV 325
++LS+ +P+V LGTW P GKV ++AV A++AGY HID AY Y E +V
Sbjct: 5 VELSTKAKMPIVGLGTWKS--PLGKV-------KEAVKVAIDAGYRHIDCAYVYQNEHEV 55
Query: 326 GRALXQEILRRT*KRIYLY 382
G A+ ++I + KR L+
Sbjct: 56 GEAIQEKIQEKAVKREDLF 74
Score = 52.4 bits (120), Expect = 2e-06
Identities = 39/121 (32%), Positives = 60/121 (49%), Gaps = 12/121 (9%)
Frame = +3
Query: 354 EGLKRESIFITTKLWNSYHEREQVIPALRKSLXKSQLG------IRRPVF----DSLAHS 503
+ +KRE +FI +KLW ++ ER V A K+L +L I P D L
Sbjct: 66 KAVKREDLFIVSKLWPTFFERPLVRKAFEKTLKDLKLSYLDVYLIHWPQGFKSGDDLFPK 125
Query: 504 YV*ERYLARHVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDS-GLE-KPSALQI 677
+ FLD W M + GL K++G+SNF+ QI+++++ GL+ KP Q+
Sbjct: 126 DDKGNAIGGKATFLDAWEAMEELVDEGLVKALGVSNFSHFQIEKLLNKPGLKYKPVTNQV 185
Query: 678 E 680
E
Sbjct: 186 E 186
Score = 32.7 bits (71), Expect = 2.1
Identities = 13/26 (50%), Positives = 16/26 (61%)
Frame = +1
Query: 448 LXNLNLEYVDLYLIHWPIAMFENDTL 525
L +L L Y+D+YLIHWP D L
Sbjct: 97 LKDLKLSYLDVYLIHWPQGFKSGDDL 122
>BC002862-1|AAH02862.1| 307|Homo sapiens AKR1CL2 protein protein.
Length = 307
Score = 53.6 bits (123), Expect = 1e-06
Identities = 27/50 (54%), Positives = 34/50 (68%), Gaps = 2/50 (4%)
Frame = +3
Query: 537 DFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDS-GLE-KPSALQIE 680
DFLDTW M D GL K+IG+SNFN EQ++R+++ GL KP QIE
Sbjct: 147 DFLDTWEAMEDLVITGLVKNIGVSNFNHEQLERLLNKPGLRFKPLTNQIE 196
Score = 37.1 bits (82), Expect = 0.099
Identities = 24/62 (38%), Positives = 32/62 (51%)
Frame = +2
Query: 164 GNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQVGRALXQ 343
G+IP V L +W GKV + AV A++AGY H D AY Y E +VG +
Sbjct: 2 GDIPAVGLSSWKAS--PGKVTE-------AVKEAIDAGYRHFDCAYFYHNEREVGAGIRC 52
Query: 344 EI 349
+I
Sbjct: 53 KI 54
Score = 37.1 bits (82), Expect = 0.099
Identities = 19/41 (46%), Positives = 26/41 (63%), Gaps = 1/41 (2%)
Frame = +3
Query: 345 KFSEG-LKRESIFITTKLWNSYHEREQVIPALRKSLXKSQL 464
K EG ++RE +FI TKLW + H++ V A RKSL +L
Sbjct: 53 KIKEGAVRREDLFIATKLWCTCHKKSLVETACRKSLKALKL 93
Score = 31.9 bits (69), Expect = 3.7
Identities = 12/18 (66%), Positives = 14/18 (77%)
Frame = +1
Query: 448 LXNLNLEYVDLYLIHWPI 501
L L L Y+DLYLIHWP+
Sbjct: 88 LKALKLNYLDLYLIHWPM 105
>AF263242-1|AAK58523.1| 320|Homo sapiens aldo-keto reductase
loopADR protein.
Length = 320
Score = 53.6 bits (123), Expect = 1e-06
Identities = 27/50 (54%), Positives = 34/50 (68%), Gaps = 2/50 (4%)
Frame = +3
Query: 537 DFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDS-GLE-KPSALQIE 680
DFLDTW M D GL K+IG+SNFN EQ++R+++ GL KP QIE
Sbjct: 147 DFLDTWEAMEDLVITGLVKNIGVSNFNHEQLERLLNKPGLRFKPLTNQIE 196
Score = 37.1 bits (82), Expect = 0.099
Identities = 24/62 (38%), Positives = 32/62 (51%)
Frame = +2
Query: 164 GNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQVGRALXQ 343
G+IP V L +W GKV + AV A++AGY H D AY Y E +VG +
Sbjct: 2 GDIPAVGLSSWKAS--PGKVTE-------AVKEAIDAGYRHFDCAYFYHNEREVGAGIRC 52
Query: 344 EI 349
+I
Sbjct: 53 KI 54
Score = 37.1 bits (82), Expect = 0.099
Identities = 19/41 (46%), Positives = 26/41 (63%), Gaps = 1/41 (2%)
Frame = +3
Query: 345 KFSEG-LKRESIFITTKLWNSYHEREQVIPALRKSLXKSQL 464
K EG ++RE +FI TKLW + H++ V A RKSL +L
Sbjct: 53 KIKEGAVRREDLFIATKLWCTCHKKSLVETACRKSLKALKL 93
Score = 31.9 bits (69), Expect = 3.7
Identities = 12/18 (66%), Positives = 14/18 (77%)
Frame = +1
Query: 448 LXNLNLEYVDLYLIHWPI 501
L L L Y+DLYLIHWP+
Sbjct: 88 LKALKLNYLDLYLIHWPM 105
>AB055603-1|BAC54568.1| 307|Homo sapiens aldo-keto reductase
related protein 4 protein.
Length = 307
Score = 53.6 bits (123), Expect = 1e-06
Identities = 27/50 (54%), Positives = 34/50 (68%), Gaps = 2/50 (4%)
Frame = +3
Query: 537 DFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDS-GLE-KPSALQIE 680
DFLDTW M D GL K+IG+SNFN EQ++R+++ GL KP QIE
Sbjct: 147 DFLDTWEAMEDLVITGLVKNIGVSNFNHEQLERLLNKPGLRFKPLTNQIE 196
Score = 37.1 bits (82), Expect = 0.099
Identities = 24/62 (38%), Positives = 32/62 (51%)
Frame = +2
Query: 164 GNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQVGRALXQ 343
G+IP V L +W GKV + AV A++AGY H D AY Y E +VG +
Sbjct: 2 GDIPAVGLSSWKAS--PGKVTE-------AVKEAIDAGYRHFDCAYFYHNEREVGAGIRC 52
Query: 344 EI 349
+I
Sbjct: 53 KI 54
Score = 37.1 bits (82), Expect = 0.099
Identities = 19/41 (46%), Positives = 26/41 (63%), Gaps = 1/41 (2%)
Frame = +3
Query: 345 KFSEG-LKRESIFITTKLWNSYHEREQVIPALRKSLXKSQL 464
K EG ++RE +FI TKLW + H++ V A RKSL +L
Sbjct: 53 KIKEGAVRREDLFIATKLWCTCHKKSLVETACRKSLKALKL 93
Score = 31.9 bits (69), Expect = 3.7
Identities = 12/18 (66%), Positives = 14/18 (77%)
Frame = +1
Query: 448 LXNLNLEYVDLYLIHWPI 501
L L L Y+DLYLIHWP+
Sbjct: 88 LKALKLNYLDLYLIHWPM 105
>BC005387-1|AAH05387.1| 316|Homo sapiens aldo-keto reductase family
1, member B1 (aldose reductase) protein.
Length = 316
Score = 52.0 bits (119), Expect = 3e-06
Identities = 42/119 (35%), Positives = 62/119 (52%), Gaps = 12/119 (10%)
Frame = +3
Query: 360 LKRESIFITTKLWNSYHEREQVIPALRKSLXKSQLG------IRRPV-FDSLAHSYV*ER 518
+KRE +FI +KLW +YHE+ V A +K+L +L I P F + +
Sbjct: 68 VKREELFIVSKLWCTYHEKGLVKGACQKTLSDLKLDYLDLYLIHWPTGFKPGKEFFPLDE 127
Query: 519 ---YLARHVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDS-GLE-KPSALQIE 680
+ + LDT M + GL K+IGISNFN Q++ I++ GL+ KP+ QIE
Sbjct: 128 SGNVVPSDTNILDTRAAMEELVDEGLVKAIGISNFNHLQVEMILNKPGLKYKPAVNQIE 186
Score = 49.2 bits (112), Expect = 2e-05
Identities = 28/79 (35%), Positives = 46/79 (58%)
Frame = +2
Query: 146 LQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQV 325
L L++G +P++ LGTW P G+V + AV A++ GY HID A+ Y E++V
Sbjct: 5 LLLNNGAKMPILGLGTWKS--PPGQVTE-------AVKVAIDVGYRHIDCAHVYQNENEV 55
Query: 326 GRALXQEILRRT*KRIYLY 382
G A+ +++ + KR L+
Sbjct: 56 GVAIQEKLREQVVKREELF 74
Score = 33.5 bits (73), Expect = 1.2
Identities = 12/17 (70%), Positives = 15/17 (88%)
Frame = +1
Query: 448 LXNLNLEYVDLYLIHWP 498
L +L L+Y+DLYLIHWP
Sbjct: 97 LSDLKLDYLDLYLIHWP 113
>AB040821-1|BAC54566.1| 263|Homo sapiens aldo-keto reductase
related protein 2 protein.
Length = 263
Score = 51.6 bits (118), Expect = 4e-06
Identities = 26/49 (53%), Positives = 33/49 (67%), Gaps = 2/49 (4%)
Frame = +3
Query: 537 DFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDS-GLE-KPSALQI 677
DFLDTW M D GL K+IG+SNFN EQ++R+++ GL KP QI
Sbjct: 147 DFLDTWEAMEDLVITGLVKNIGVSNFNHEQLERLLNKPGLRFKPLTNQI 195
Score = 37.1 bits (82), Expect = 0.099
Identities = 24/62 (38%), Positives = 32/62 (51%)
Frame = +2
Query: 164 GNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQVGRALXQ 343
G+IP V L +W GKV + AV A++AGY H D AY Y E +VG +
Sbjct: 2 GDIPAVGLSSWKAS--PGKVTE-------AVKEAIDAGYRHFDCAYFYHNEREVGAGIRC 52
Query: 344 EI 349
+I
Sbjct: 53 KI 54
Score = 37.1 bits (82), Expect = 0.099
Identities = 19/41 (46%), Positives = 26/41 (63%), Gaps = 1/41 (2%)
Frame = +3
Query: 345 KFSEG-LKRESIFITTKLWNSYHEREQVIPALRKSLXKSQL 464
K EG ++RE +FI TKLW + H++ V A RKSL +L
Sbjct: 53 KIKEGAVRREDLFIATKLWCTCHKKSLVETACRKSLKALKL 93
Score = 31.9 bits (69), Expect = 3.7
Identities = 12/18 (66%), Positives = 14/18 (77%)
Frame = +1
Query: 448 LXNLNLEYVDLYLIHWPI 501
L L L Y+DLYLIHWP+
Sbjct: 88 LKALKLNYLDLYLIHWPM 105
>AB040820-1|BAC54565.1| 250|Homo sapiens aldo-keto reductase
related protein 1 protein.
Length = 250
Score = 51.6 bits (118), Expect = 4e-06
Identities = 26/49 (53%), Positives = 33/49 (67%), Gaps = 2/49 (4%)
Frame = +3
Query: 537 DFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDS-GLE-KPSALQI 677
DFLDTW M D GL K+IG+SNFN EQ++R+++ GL KP QI
Sbjct: 147 DFLDTWEAMEDLVITGLVKNIGVSNFNHEQLERLLNKPGLRFKPLTNQI 195
Score = 37.1 bits (82), Expect = 0.099
Identities = 24/62 (38%), Positives = 32/62 (51%)
Frame = +2
Query: 164 GNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQVGRALXQ 343
G+IP V L +W GKV + AV A++AGY H D AY Y E +VG +
Sbjct: 2 GDIPAVGLSSWKAS--PGKVTE-------AVKEAIDAGYRHFDCAYFYHNEREVGAGIRC 52
Query: 344 EI 349
+I
Sbjct: 53 KI 54
Score = 37.1 bits (82), Expect = 0.099
Identities = 19/41 (46%), Positives = 26/41 (63%), Gaps = 1/41 (2%)
Frame = +3
Query: 345 KFSEG-LKRESIFITTKLWNSYHEREQVIPALRKSLXKSQL 464
K EG ++RE +FI TKLW + H++ V A RKSL +L
Sbjct: 53 KIKEGAVRREDLFIATKLWCTCHKKSLVETACRKSLKALKL 93
Score = 31.9 bits (69), Expect = 3.7
Identities = 12/18 (66%), Positives = 14/18 (77%)
Frame = +1
Query: 448 LXNLNLEYVDLYLIHWPI 501
L L L Y+DLYLIHWP+
Sbjct: 88 LKALKLNYLDLYLIHWPM 105
>BC101205-1|AAI01206.1| 129|Homo sapiens aldo-keto reductase family
1, member C-like 1 protein.
Length = 129
Score = 48.0 bits (109), Expect = 5e-05
Identities = 26/77 (33%), Positives = 45/77 (58%), Gaps = 1/77 (1%)
Frame = +2
Query: 143 TLQLSSGGNIPVVALGTWL-GHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIED 319
+++L+ G +PV+ GT+ H PK + + T A++ G+ HID+AY Y E+
Sbjct: 10 SVRLNDGPFMPVLGFGTYAPDHTPKSQAAEATK-------VAIDVGFRHIDSAYLYQNEE 62
Query: 320 QVGRALXQEILRRT*KR 370
+VG+A+ ++I T KR
Sbjct: 63 EVGQAIWEKIADGTVKR 79
Score = 38.7 bits (86), Expect = 0.032
Identities = 19/39 (48%), Positives = 26/39 (66%), Gaps = 1/39 (2%)
Frame = +3
Query: 342 KKFSEG-LKRESIFITTKLWNSYHEREQVIPALRKSLXK 455
+K ++G +KRE IF T KLW ++ E V PAL +SL K
Sbjct: 70 EKIADGTVKREEIFYTIKLWATFFRAELVHPALERSLKK 108
>BC101204-1|AAI01205.1| 129|Homo sapiens aldo-keto reductase family
1, member C-like 1 protein.
Length = 129
Score = 48.0 bits (109), Expect = 5e-05
Identities = 26/77 (33%), Positives = 45/77 (58%), Gaps = 1/77 (1%)
Frame = +2
Query: 143 TLQLSSGGNIPVVALGTWL-GHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIED 319
+++L+ G +PV+ GT+ H PK + + T A++ G+ HID+AY Y E+
Sbjct: 10 SVRLNDGPFMPVLGFGTYAPDHTPKSQAAEATK-------VAIDVGFRHIDSAYLYQNEE 62
Query: 320 QVGRALXQEILRRT*KR 370
+VG+A+ ++I T KR
Sbjct: 63 EVGQAIWEKIADGTVKR 79
Score = 38.7 bits (86), Expect = 0.032
Identities = 19/39 (48%), Positives = 26/39 (66%), Gaps = 1/39 (2%)
Frame = +3
Query: 342 KKFSEG-LKRESIFITTKLWNSYHEREQVIPALRKSLXK 455
+K ++G +KRE IF T KLW ++ E V PAL +SL K
Sbjct: 70 EKIADGTVKREEIFYTIKLWATFFRAELVHPALERSLKK 108
>AL391427-2|CAI14727.1| 302|Homo sapiens aldo-keto reductase family
1, member C-like 1 protein.
Length = 302
Score = 48.0 bits (109), Expect = 5e-05
Identities = 26/77 (33%), Positives = 45/77 (58%), Gaps = 1/77 (1%)
Frame = +2
Query: 143 TLQLSSGGNIPVVALGTWL-GHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIED 319
+++L+ G +PV+ GT+ H PK + + T A++ G+ HID+AY Y E+
Sbjct: 10 SVRLNDGPFMPVLGFGTYAPDHTPKSQAAEATK-------VAIDVGFRHIDSAYLYQNEE 62
Query: 320 QVGRALXQEILRRT*KR 370
+VG+A+ ++I T KR
Sbjct: 63 EVGQAIWEKIADGTVKR 79
Score = 38.7 bits (86), Expect = 0.032
Identities = 19/39 (48%), Positives = 26/39 (66%), Gaps = 1/39 (2%)
Frame = +3
Query: 342 KKFSEG-LKRESIFITTKLWNSYHEREQVIPALRKSLXK 455
+K ++G +KRE IF T KLW ++ E V PAL +SL K
Sbjct: 70 EKIADGTVKREEIFYTIKLWATFFRAELVHPALERSLKK 108
>AL355303-1|CAI14201.1| 302|Homo sapiens aldo-keto reductase family
1, member C-like 1 protein.
Length = 302
Score = 48.0 bits (109), Expect = 5e-05
Identities = 26/77 (33%), Positives = 45/77 (58%), Gaps = 1/77 (1%)
Frame = +2
Query: 143 TLQLSSGGNIPVVALGTWL-GHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIED 319
+++L+ G +PV+ GT+ H PK + + T A++ G+ HID+AY Y E+
Sbjct: 10 SVRLNDGPFMPVLGFGTYAPDHTPKSQAAEATK-------VAIDVGFRHIDSAYLYQNEE 62
Query: 320 QVGRALXQEILRRT*KR 370
+VG+A+ ++I T KR
Sbjct: 63 EVGQAIWEKIADGTVKR 79
Score = 38.7 bits (86), Expect = 0.032
Identities = 19/39 (48%), Positives = 26/39 (66%), Gaps = 1/39 (2%)
Frame = +3
Query: 342 KKFSEG-LKRESIFITTKLWNSYHEREQVIPALRKSLXK 455
+K ++G +KRE IF T KLW ++ E V PAL +SL K
Sbjct: 70 EKIADGTVKREEIFYTIKLWATFFRAELVHPALERSLKK 108
>AK131335-1|BAD18494.1| 129|Homo sapiens protein ( Homo sapiens
cDNA FLJ16347 fis, clone TESTI2036288, moderately
similar to PROSTAGLANDIN-F SYNTHASE 1 (EC 1.1.1.188). ).
Length = 129
Score = 48.0 bits (109), Expect = 5e-05
Identities = 26/77 (33%), Positives = 45/77 (58%), Gaps = 1/77 (1%)
Frame = +2
Query: 143 TLQLSSGGNIPVVALGTWL-GHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIED 319
+++L+ G +PV+ GT+ H PK + + T A++ G+ HID+AY Y E+
Sbjct: 10 SVRLNDGPFMPVLGFGTYAPDHTPKSQAAEATK-------VAIDVGFRHIDSAYLYQNEE 62
Query: 320 QVGRALXQEILRRT*KR 370
+VG+A+ ++I T KR
Sbjct: 63 EVGQAIWEKIADGTVKR 79
Score = 38.7 bits (86), Expect = 0.032
Identities = 19/39 (48%), Positives = 26/39 (66%), Gaps = 1/39 (2%)
Frame = +3
Query: 342 KKFSEG-LKRESIFITTKLWNSYHEREQVIPALRKSLXK 455
+K ++G +KRE IF T KLW ++ E V PAL +SL K
Sbjct: 70 EKIADGTVKREEIFYTIKLWATFFRAELVHPALERSLKK 108
>AL355480-2|CAI22458.1| 147|Homo sapiens aldo-keto reductase family
1, member A1 (aldehydela) protein.
Length = 147
Score = 47.2 bits (107), Expect = 9e-05
Identities = 27/66 (40%), Positives = 38/66 (57%)
Frame = +2
Query: 152 LSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQVGR 331
L +G +P++ LGTW K + QV + AV YAL GY HID A YG E ++G
Sbjct: 8 LHTGQKMPLIGLGTW-----KSEPGQV----KAAVKYALSVGYRHIDCAAIYGNEPEIGE 58
Query: 332 ALXQEI 349
AL +++
Sbjct: 59 ALKEDV 64
Score = 44.4 bits (100), Expect = 7e-04
Identities = 19/37 (51%), Positives = 26/37 (70%)
Frame = +3
Query: 354 EGLKRESIFITTKLWNSYHEREQVIPALRKSLXKSQL 464
+ + RE +F+T+KLWN+ H E V PALRK+L QL
Sbjct: 68 KAVPREELFVTSKLWNTKHHPEDVEPALRKTLADLQL 104
Score = 35.9 bits (79), Expect = 0.23
Identities = 14/24 (58%), Positives = 17/24 (70%)
Frame = +1
Query: 448 LXNLNLEYVDLYLIHWPIAMFEND 519
L +L LEY+DLYL+HWP A D
Sbjct: 99 LADLQLEYLDLYLMHWPYAFERGD 122
>AB037902-1|BAA92887.1| 130|Homo sapiens truncated aldo-keto
reductase protein.
Length = 130
Score = 45.2 bits (102), Expect = 4e-04
Identities = 25/76 (32%), Positives = 47/76 (61%)
Frame = +2
Query: 143 TLQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQ 322
+++L+ G +P++ GT + + V ++N E+AV A++ GY HID+AY + E+
Sbjct: 8 SVKLNDGKFMPILGFGTSVARK-----VAMSN-VEEAVQVAIDVGYRHIDSAYTHLNEEG 61
Query: 323 VGRALXQEILRRT*KR 370
+G+A+ ++I T KR
Sbjct: 62 IGQAIRKKIANGTVKR 77
Score = 35.9 bits (79), Expect = 0.23
Identities = 19/42 (45%), Positives = 25/42 (59%), Gaps = 1/42 (2%)
Frame = +3
Query: 342 KKFSEG-LKRESIFITTKLWNSYHEREQVIPALRKSLXKSQL 464
KK + G +KR+ IF TTK+W ++ E V L SL K QL
Sbjct: 68 KKIANGTVKRKDIFYTTKVWGTFSRPELVQRGLEMSLKKLQL 109
>AB028065-1|BAA88489.1| 67|Homo sapiens prostaglandin F synthase
protein.
Length = 67
Score = 44.0 bits (99), Expect = 9e-04
Identities = 22/45 (48%), Positives = 29/45 (64%), Gaps = 2/45 (4%)
Frame = +3
Query: 534 VDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDS-GLE-KP 662
VD TW M K GL KSIG+SNFN+ Q++ I++ GL+ KP
Sbjct: 19 VDLCTTWEAMEKCKDAGLAKSIGVSNFNRRQLEMILNKPGLKYKP 63
>AK058142-1|BAB71682.1| 146|Homo sapiens protein ( Homo sapiens
cDNA FLJ25413 fis, clone TST03402, highly similar to
3-OXO-5-BETA-STEROID 4-DEHYDROGENASE (EC 1.3.99.6). ).
Length = 146
Score = 43.2 bits (97), Expect = 0.002
Identities = 22/57 (38%), Positives = 35/57 (61%), Gaps = 2/57 (3%)
Frame = +3
Query: 516 RYLARHVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDS-GLE-KPSALQIE 680
++L + TW M K GL KS+G+SNFN+ Q++ I++ GL+ KP + Q+E
Sbjct: 17 KWLYHKSNLCATWEAMEACKDAGLVKSLGVSNFNRRQLELILNKPGLKHKPVSNQVE 73
>AB040822-1|BAC54567.1| 222|Homo sapiens aldo-keto reductase
related protein 3 protein.
Length = 222
Score = 37.1 bits (82), Expect = 0.099
Identities = 24/62 (38%), Positives = 32/62 (51%)
Frame = +2
Query: 164 GNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQVGRALXQ 343
G+IP V L +W GKV + AV A++AGY H D AY Y E +VG +
Sbjct: 2 GDIPAVGLSSWKAS--PGKVTE-------AVKEAIDAGYRHFDCAYFYHNEREVGAGIRC 52
Query: 344 EI 349
+I
Sbjct: 53 KI 54
Score = 37.1 bits (82), Expect = 0.099
Identities = 19/41 (46%), Positives = 26/41 (63%), Gaps = 1/41 (2%)
Frame = +3
Query: 345 KFSEG-LKRESIFITTKLWNSYHEREQVIPALRKSLXKSQL 464
K EG ++RE +FI TKLW + H++ V A RKSL +L
Sbjct: 53 KIKEGAVRREDLFIATKLWCTCHKKSLVETACRKSLKALKL 93
Score = 31.9 bits (69), Expect = 3.7
Identities = 12/18 (66%), Positives = 14/18 (77%)
Frame = +1
Query: 448 LXNLNLEYVDLYLIHWPI 501
L L L Y+DLYLIHWP+
Sbjct: 88 LKALKLNYLDLYLIHWPM 105
>AJ421033-1|CAD13145.1| 326|Homo sapiens TPIP beta protein.
Length = 326
Score = 31.1 bits (67), Expect = 6.5
Identities = 18/79 (22%), Positives = 42/79 (53%)
Frame = +3
Query: 291 TPHTNMESRTKWEGPXTKKFSEGLKRESIFITTKLWNSYHEREQVIPALRKSLXKSQLGI 470
+PHT+ P +K+++ ++ + I ++++ H++ Q+ +R+ + +++
Sbjct: 22 SPHTSEFKGAALVSPISKRWTHLVRLLRLIILIRIFHLLHQKRQLEKLMRRLVSENKRRY 81
Query: 471 RRPVFDSLAHSYV*ERYLA 527
R FD L +YV ER +A
Sbjct: 82 TRDGFD-LDLTYVTERIIA 99
>BC029488-1|AAH29488.1| 294|Homo sapiens sperm acrosome associated
1 protein.
Length = 294
Score = 30.7 bits (66), Expect = 8.6
Identities = 17/56 (30%), Positives = 25/56 (44%)
Frame = +2
Query: 98 CLSALCFTSADLIVPTLQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYA 265
C + L T L++ LQ + G N+ L H +G+ ND+E A YA
Sbjct: 8 CSAGLLMTVGWLLLAGLQSARGTNVTAAVQDAGLAHEGEGEEETENNDSETAENYA 63
>AL136096-1|CAI19915.1| 294|Homo sapiens sperm acrosome associated
1 protein.
Length = 294
Score = 30.7 bits (66), Expect = 8.6
Identities = 17/56 (30%), Positives = 25/56 (44%)
Frame = +2
Query: 98 CLSALCFTSADLIVPTLQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYA 265
C + L T L++ LQ + G N+ L H +G+ ND+E A YA
Sbjct: 8 CSAGLLMTVGWLLLAGLQSARGTNVTAAVQDAGLAHEGEGEEETENNDSETAENYA 63
>AF203447-1|AAG31422.1| 294|Homo sapiens sperm acrosome membrane
protein SAMP32 protein.
Length = 294
Score = 30.7 bits (66), Expect = 8.6
Identities = 17/56 (30%), Positives = 25/56 (44%)
Frame = +2
Query: 98 CLSALCFTSADLIVPTLQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYA 265
C + L T L++ LQ + G N+ L H +G+ ND+E A YA
Sbjct: 8 CSAGLLMTVGWLLLAGLQSARGTNVTAAVQDAGLAHEGEGEEETENNDSETAENYA 63
Database: human
Posted date: Oct 23, 2007 1:18 PM
Number of letters in database: 76,859,062
Number of sequences in database: 237,096
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 127,890,487
Number of Sequences: 237096
Number of extensions: 2876095
Number of successful extensions: 12329
Number of sequences better than 10.0: 96
Number of HSP's better than 10.0 without gapping: 10955
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 11965
length of database: 76,859,062
effective HSP length: 90
effective length of database: 55,520,422
effective search space used: 13269380858
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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