BLASTX 2.2.12 [Aug-07-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= MFBP01_F_I07 (921 letters) Database: uniref50 1,657,284 sequences; 575,637,011 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value UniRef50_Q7PCV3 Cluster: ENSANGP00000031808; n=9; Endopterygota|... 229 8e-59 UniRef50_Q2LZ66 Cluster: GA19341-PA; n=2; Endopterygota|Rep: GA1... 210 4e-53 UniRef50_Q9VTL0 Cluster: CG6083-PA; n=4; Diptera|Rep: CG6083-PA ... 204 2e-51 UniRef50_P45376 Cluster: Aldose reductase; n=21; Bilateria|Rep: ... 201 2e-50 UniRef50_P15121 Cluster: Aldose reductase; n=72; Eumetazoa|Rep: ... 197 3e-49 UniRef50_UPI00015B56A2 Cluster: PREDICTED: similar to GA10458-PA... 192 1e-47 UniRef50_Q9NAI5 Cluster: Putative uncharacterized protein; n=3; ... 187 4e-46 UniRef50_Q8CI22 Cluster: 2310005E10Rik protein; n=30; Tetrapoda|... 186 5e-46 UniRef50_P14550 Cluster: Alcohol dehydrogenase [NADP+]; n=44; Bi... 175 1e-42 UniRef50_Q17DN0 Cluster: Aldo-keto reductase; n=5; Culicidae|Rep... 170 5e-41 UniRef50_Q7QK25 Cluster: ENSANGP00000019775; n=2; Anopheles gamb... 166 6e-40 UniRef50_Q8K023 Cluster: Aldo-keto reductase family 1 member C18... 162 1e-38 UniRef50_UPI00015B56A3 Cluster: PREDICTED: similar to aldo-keto ... 161 2e-38 UniRef50_A5KSS3 Cluster: Aldehyde reductase; n=1; candidate divi... 161 2e-38 UniRef50_Q2S340 Cluster: Aldehyde reductase; n=10; Bacteria|Rep:... 160 5e-38 UniRef50_Q0VGY1 Cluster: 3-alpha-hydroxysteroid dehydrogenase; n... 159 7e-38 UniRef50_UPI0000588153 Cluster: PREDICTED: hypothetical protein;... 159 9e-38 UniRef50_A7SIT3 Cluster: Predicted protein; n=1; Nematostella ve... 157 3e-37 UniRef50_P27800 Cluster: Aldehyde reductase 1; n=18; root|Rep: A... 157 5e-37 UniRef50_Q54B70 Cluster: Aldehyde reductase; n=2; Dictyostelium ... 155 2e-36 UniRef50_Q96JD6-2 Cluster: Isoform 2 of Q96JD6 ; n=4; Catarrhini... 154 3e-36 UniRef50_Q96JD6 Cluster: Aldo-keto reductase family 1 member C-l... 154 3e-36 UniRef50_A2QBD7 Cluster: Catalytic activity: an alcohol + NADP(+... 154 3e-36 UniRef50_A3U9Y0 Cluster: Aldehyde reductase; n=5; Bacteroidetes|... 153 5e-36 UniRef50_Q7JVH6 Cluster: LD24696p; n=2; Sophophora|Rep: LD24696p... 153 5e-36 UniRef50_UPI000065D0BD Cluster: Homolog of Homo sapiens "AKR1B1 ... 151 2e-35 UniRef50_Q8VC28 Cluster: Aldo-keto reductase family 1 member C13... 151 3e-35 UniRef50_Q96UH3 Cluster: Aldehyde reductase; n=13; Pezizomycotin... 149 1e-34 UniRef50_A4RQH8 Cluster: Predicted protein; n=2; Ostreococcus|Re... 149 1e-34 UniRef50_UPI0000E4A7CE Cluster: PREDICTED: similar to LOC553452 ... 148 2e-34 UniRef50_Q7QVQ9 Cluster: GLP_302_44328_45269; n=1; Giardia lambl... 148 2e-34 UniRef50_Q10494 Cluster: Probable oxidoreductase C26F1.07; n=2; ... 148 2e-34 UniRef50_Q2V420 Cluster: Uncharacterized protein At2g37770.1; n=... 147 4e-34 UniRef50_Q0PGJ6 Cluster: Aldo-keto reductase; n=32; Magnoliophyt... 147 4e-34 UniRef50_P51857 Cluster: 3-oxo-5-beta-steroid 4-dehydrogenase (E... 146 7e-34 UniRef50_Q5BKE9 Cluster: LOC594893 protein; n=5; Xenopus tropica... 144 4e-33 UniRef50_Q0IBY6 Cluster: Alcohol dehydrogenase; n=2; Chroococcal... 144 4e-33 UniRef50_A2R6Z3 Cluster: Catalytic activity: an alcohol + NADP(+... 142 1e-32 UniRef50_UPI0000498F1F Cluster: oxidoreductase, aldo/keto reduct... 140 5e-32 UniRef50_A2QVE5 Cluster: Similarity: shows similarity to several... 140 6e-32 UniRef50_Q55FL3 Cluster: Aldo-keto reductase; n=2; Dictyostelium... 139 8e-32 UniRef50_Q8SSK6 Cluster: ALDOSE REDUCTASE; n=1; Encephalitozoon ... 139 8e-32 UniRef50_A2FPE2 Cluster: Oxidoreductase, aldo/keto reductase fam... 137 3e-31 UniRef50_Q9U2J5 Cluster: Putative uncharacterized protein; n=2; ... 137 4e-31 UniRef50_Q22352 Cluster: Putative uncharacterized protein T08H10... 136 6e-31 UniRef50_P38715 Cluster: NADPH-dependent aldose reductase GRE3; ... 134 3e-30 UniRef50_UPI0000E45E29 Cluster: PREDICTED: similar to aldose red... 134 4e-30 UniRef50_Q7ZA52 Cluster: Aldose reductase; n=6; Pezizomycotina|R... 134 4e-30 UniRef50_Q2UGR1 Cluster: Aldo/keto reductase family proteins; n=... 133 5e-30 UniRef50_Q1YPE5 Cluster: Aldehyde reductase; n=7; Bacteria|Rep: ... 133 7e-30 UniRef50_Q4PAT5 Cluster: Putative uncharacterized protein; n=1; ... 132 1e-29 UniRef50_Q1U9L6 Cluster: 2,5-didehydrogluconate reductase; n=3; ... 131 2e-29 UniRef50_Q5KI95 Cluster: Aldo-keto reductase, putative; n=14; Di... 131 2e-29 UniRef50_A2EYY6 Cluster: Oxidoreductase, aldo/keto reductase fam... 130 4e-29 UniRef50_Q9Y020 Cluster: 3-dehydroecdysone 3beta-reductase precu... 130 5e-29 UniRef50_Q9VHX4 Cluster: CG2767-PA; n=4; Endopterygota|Rep: CG27... 130 5e-29 UniRef50_Q7ZWA4 Cluster: Zgc:56622; n=6; cellular organisms|Rep:... 129 9e-29 UniRef50_Q5T2L2 Cluster: Aldo-keto reductase family 1 member C-l... 129 1e-28 UniRef50_UPI0000499B0E Cluster: oxidoreductase, aldo/keto reduct... 128 1e-28 UniRef50_Q4FY75 Cluster: Aldo-keto reductase-like protein; n=5; ... 127 3e-28 UniRef50_Q41399 Cluster: Chalcone reductase; n=4; eudicotyledons... 126 6e-28 UniRef50_Q8WRT0 Cluster: 3-dehydrecdysone 3b-reductase; n=1; Tri... 126 6e-28 UniRef50_Q7PLK6 Cluster: CG40064-PA; n=1; Drosophila melanogaste... 126 6e-28 UniRef50_Q6TY50 Cluster: Reductase 2; n=10; Magnoliophyta|Rep: R... 126 1e-27 UniRef50_A2EHN6 Cluster: Oxidoreductase, aldo/keto reductase fam... 126 1e-27 UniRef50_Q1IN88 Cluster: Aldehyde reductase; n=5; Bacteria|Rep: ... 125 1e-27 UniRef50_UPI000023D0F1 Cluster: hypothetical protein FG03517.1; ... 124 2e-27 UniRef50_Q16K66 Cluster: Aldo-keto reductase; n=2; Aedes aegypti... 124 2e-27 UniRef50_A7PNI3 Cluster: Chromosome chr1 scaffold_22, whole geno... 124 3e-27 UniRef50_Q6RZX1 Cluster: Gld1; n=22; Pezizomycotina|Rep: Gld1 - ... 122 1e-26 UniRef50_P28475 Cluster: NADP-dependent D-sorbitol-6-phosphate d... 122 1e-26 UniRef50_Q6CFG7 Cluster: Yarrowia lipolytica chromosome B of str... 122 1e-26 UniRef50_P23901 Cluster: Aldose reductase; n=9; Poaceae|Rep: Ald... 122 1e-26 UniRef50_Q17DN1 Cluster: Aldo-keto reductase; n=1; Aedes aegypti... 122 2e-26 UniRef50_UPI0000D9A956 Cluster: PREDICTED: similar to aldo-keto ... 121 3e-26 UniRef50_Q17G72 Cluster: Aldo-keto reductase; n=9; Endopterygota... 121 3e-26 UniRef50_P14065 Cluster: Protein GCY; n=13; Saccharomycetales|Re... 121 3e-26 UniRef50_Q23320 Cluster: Putative uncharacterized protein; n=4; ... 120 4e-26 UniRef50_Q6NII7 Cluster: Putative oxidoreductase; n=2; Corynebac... 120 5e-26 UniRef50_A1D4E3 Cluster: D-xylose reductase (Xyl1), putative; n=... 119 9e-26 UniRef50_P26690 Cluster: NAD(P)H-dependent 6'-deoxychalcone synt... 119 9e-26 UniRef50_P22045 Cluster: Probable reductase; n=101; cellular org... 119 1e-25 UniRef50_A7CWF9 Cluster: Aldehyde reductase; n=2; Bacteria|Rep: ... 117 4e-25 UniRef50_Q03TW0 Cluster: Aldo/keto reductase of diketogulonate r... 117 5e-25 UniRef50_UPI00015B4B22 Cluster: PREDICTED: similar to GA15457-PA... 116 6e-25 UniRef50_Q0CLQ2 Cluster: Putative uncharacterized protein; n=1; ... 116 6e-25 UniRef50_Q01J82 Cluster: OSIGBa0152K17.5 protein; n=28; Magnolio... 116 9e-25 UniRef50_A6W8E7 Cluster: 2,5-didehydrogluconate reductase; n=3; ... 116 1e-24 UniRef50_A6RKL9 Cluster: Putative uncharacterized protein; n=3; ... 116 1e-24 UniRef50_Q03PG5 Cluster: Aldo/keto reductase of diketogulonate r... 114 3e-24 UniRef50_Q01HB5 Cluster: OSIGBa0136O08-OSIGBa0153H12.9 protein; ... 114 3e-24 UniRef50_A5E082 Cluster: GCY protein; n=4; Saccharomycetales|Rep... 114 3e-24 UniRef50_UPI00015B40FA Cluster: PREDICTED: similar to CG2767-PA;... 114 3e-24 UniRef50_Q8F1G4 Cluster: Aldehyde reductase; n=8; Bacteria|Rep: ... 113 5e-24 UniRef50_Q7XY49 Cluster: Mannose 6-phosphate reductase; n=1; Gri... 113 6e-24 UniRef50_Q9HGY0 Cluster: Glycerol dehydrogenase; n=8; Saccharomy... 113 6e-24 UniRef50_Q6C2L0 Cluster: Yarrowia lipolytica chromosome F of str... 113 6e-24 UniRef50_P70883 Cluster: AkrI; n=1; Butyrivibrio fibrisolvens|Re... 113 8e-24 UniRef50_Q5FK98 Cluster: Oxidoreductase; n=8; Lactobacillales|Re... 112 1e-23 UniRef50_A6ESC0 Cluster: ARA1; n=1; unidentified eubacterium SCB... 112 1e-23 UniRef50_Q9FJK0 Cluster: Aldose reductase-like protein; n=3; cor... 112 1e-23 UniRef50_Q7PM68 Cluster: ENSANGP00000014386; n=1; Anopheles gamb... 112 1e-23 UniRef50_Q88SL1 Cluster: Oxidoreductase; n=51; Lactobacillales|R... 111 2e-23 UniRef50_P06632 Cluster: 2,5-diketo-D-gluconic acid reductase A;... 111 2e-23 UniRef50_Q5HR31 Cluster: Oxidoreductase, aldo/keto reductase fam... 111 3e-23 UniRef50_Q8J0K1 Cluster: 4-dihydromethyltrisporate dehydrogenase... 110 4e-23 UniRef50_P38115 Cluster: D-arabinose dehydrogenase [NAD(P)+] hea... 110 4e-23 UniRef50_UPI0000519CC2 Cluster: PREDICTED: similar to CG2767-PA;... 110 6e-23 UniRef50_Q7N0E4 Cluster: 2,5-diketo-D-gluconic acid reductase A;... 110 6e-23 UniRef50_Q4Q5N9 Cluster: Prostaglandin f synthase, putative; n=7... 109 1e-22 UniRef50_Q9ZBW7 Cluster: Putative oxidoreductase; n=2; Actinomyc... 109 1e-22 UniRef50_Q83N50 Cluster: 2,5-diketo-D-gluconic acid reductase; n... 108 2e-22 UniRef50_Q4JX70 Cluster: Putative oxidoreductase; n=1; Corynebac... 108 2e-22 UniRef50_A7BA05 Cluster: Putative uncharacterized protein; n=1; ... 108 2e-22 UniRef50_Q9X0A2 Cluster: Oxidoreductase, aldo/keto reductase fam... 107 4e-22 UniRef50_A6WDZ5 Cluster: Aldo/keto reductase; n=5; Bacteria|Rep:... 107 5e-22 UniRef50_A3LTU8 Cluster: D-arabinose dehydrogenase; n=5; Sacchar... 106 7e-22 UniRef50_Q05KR9 Cluster: Benzil reductase; n=5; Bacillales|Rep: ... 106 9e-22 UniRef50_A2QL02 Cluster: Putative frameshift; n=1; Aspergillus n... 106 9e-22 UniRef50_UPI00006CD296 Cluster: oxidoreductase, aldo/keto reduct... 105 2e-21 UniRef50_Q968S3 Cluster: Aldoketoreductase-like protein; n=1; Or... 105 2e-21 UniRef50_Q7R2T6 Cluster: GLP_291_56367_57278; n=1; Giardia lambl... 105 2e-21 UniRef50_Q838E0 Cluster: Oxidoreductase, aldo/keto reductase fam... 104 4e-21 UniRef50_Q41E86 Cluster: 2,5-didehydrogluconate reductase; n=2; ... 103 5e-21 UniRef50_Q03XK0 Cluster: Aldo/keto reductase of diketogulonate r... 103 5e-21 UniRef50_Q4PDR0 Cluster: Putative uncharacterized protein; n=1; ... 103 6e-21 UniRef50_Q8ET73 Cluster: 2,5-diketo-D-gluconate reductase; n=12;... 102 1e-20 UniRef50_A6LZ55 Cluster: 2,5-didehydrogluconate reductase; n=1; ... 102 1e-20 UniRef50_P82125 Cluster: 1,5-anhydro-D-fructose reductase; n=1; ... 102 1e-20 UniRef50_A2UAH0 Cluster: Aldo/keto reductase; n=1; Bacillus coag... 101 2e-20 UniRef50_A0JRJ3 Cluster: 2,5-didehydrogluconate reductase; n=3; ... 101 2e-20 UniRef50_A5AD50 Cluster: Putative uncharacterized protein; n=3; ... 101 2e-20 UniRef50_Q8ZI40 Cluster: 2,5-diketo-D-gluconic acid reductase A;... 101 2e-20 UniRef50_A7CUW0 Cluster: 2,5-didehydrogluconate reductase; n=6; ... 101 3e-20 UniRef50_Q9ZUJ6 Cluster: T2K10.1 protein; n=16; core eudicotyled... 101 3e-20 UniRef50_Q68ST9 Cluster: Reductase AKOR2; n=2; Pleurotus djamor|... 101 3e-20 UniRef50_Q03X85 Cluster: Aldo/keto reductase of diketogulonate r... 99 8e-20 UniRef50_A6NPD6 Cluster: Putative uncharacterized protein; n=3; ... 99 8e-20 UniRef50_UPI00015B5BD7 Cluster: PREDICTED: similar to aldo-keto ... 100 1e-19 UniRef50_UPI00015B4912 Cluster: PREDICTED: similar to aldo-keto ... 99 1e-19 UniRef50_Q88TV9 Cluster: Oxidoreductase; n=4; Lactobacillus|Rep:... 99 1e-19 UniRef50_Q7VG53 Cluster: Aldo-keto reductase; n=28; Bacteria|Rep... 99 1e-19 UniRef50_Q24C22 Cluster: Oxidoreductase, aldo/keto reductase fam... 98 2e-19 UniRef50_Q4P4P1 Cluster: Putative uncharacterized protein; n=1; ... 98 2e-19 UniRef50_Q929C8 Cluster: Lin2349 protein; n=12; Listeria|Rep: Li... 97 7e-19 UniRef50_A3C1Z7 Cluster: Putative uncharacterized protein; n=2; ... 97 7e-19 UniRef50_Q7G764 Cluster: Probable NAD(P)H-dependent oxidoreducta... 97 7e-19 UniRef50_Q7NB44 Cluster: ARA1; n=3; Firmicutes|Rep: ARA1 - Mycop... 96 1e-18 UniRef50_Q5FT75 Cluster: Putative 2,5-diketo-D-gluconic acid red... 96 1e-18 UniRef50_Q5TNP1 Cluster: ENSANGP00000029046; n=2; Culicidae|Rep:... 96 1e-18 UniRef50_Q4PHK0 Cluster: Putative uncharacterized protein; n=1; ... 96 1e-18 UniRef50_Q1VRG6 Cluster: YvgN; n=1; Psychroflexus torquis ATCC 7... 95 2e-18 UniRef50_A3UJS6 Cluster: Oxidoreductase; n=3; Alphaproteobacteri... 95 2e-18 UniRef50_O13848 Cluster: NADH/NADPH dependent indole-3-acetaldeh... 95 2e-18 UniRef50_Q7G765 Cluster: Probable NAD(P)H-dependent oxidoreducta... 95 2e-18 UniRef50_Q89JN4 Cluster: Oxidoreductase; n=8; Rhizobiales|Rep: O... 94 5e-18 UniRef50_Q890A0 Cluster: Oxidoreductase; n=6; Lactobacillales|Re... 93 7e-18 UniRef50_Q5FLI5 Cluster: Aldehyde reductase; n=2; Bacteria|Rep: ... 93 7e-18 UniRef50_A0JRJ6 Cluster: Aldo/keto reductase; n=2; Micrococcinea... 93 7e-18 UniRef50_Q3E9M9 Cluster: Uncharacterized protein At5g01670.2; n=... 93 7e-18 UniRef50_Q02198 Cluster: Morphine 6-dehydrogenase; n=5; Bacteria... 93 7e-18 UniRef50_Q7WSY4 Cluster: Putative aldo-keto reductase; n=1; Prop... 93 9e-18 UniRef50_A4FEB9 Cluster: 2,5-diketo-D-gluconic acid reductase; n... 93 9e-18 UniRef50_A7P424 Cluster: Chromosome chr1 scaffold_5, whole genom... 93 9e-18 UniRef50_Q5B034 Cluster: Putative uncharacterized protein; n=1; ... 93 9e-18 UniRef50_Q5FKI1 Cluster: Reductase-dehydrogenase; n=1; Lactobaci... 93 1e-17 UniRef50_Q1RFP0 Cluster: 2,5-diketo-D-gluconic acid reductase A;... 92 2e-17 UniRef50_A0JX62 Cluster: 2,5-didehydrogluconate reductase; n=9; ... 92 2e-17 UniRef50_UPI00006CCCD7 Cluster: oxidoreductase, aldo/keto reduct... 92 2e-17 UniRef50_Q28P63 Cluster: Aldo/keto reductase; n=4; Rhodobacterac... 92 2e-17 UniRef50_A5PDA8 Cluster: Putative oxidoreductase protein; n=1; E... 91 3e-17 UniRef50_Q4V008 Cluster: Oxidoreductase; n=4; Proteobacteria|Rep... 91 4e-17 UniRef50_Q15NA5 Cluster: Aldo/keto reductase; n=2; Gammaproteoba... 91 4e-17 UniRef50_Q14LU6 Cluster: Putative aldo/keto reductase oxidoreduc... 91 4e-17 UniRef50_A3VHZ9 Cluster: Oxidoreductase; n=1; Rhodobacterales ba... 91 4e-17 UniRef50_Q8ZH36 Cluster: 2,5-diketo-D-gluconic acid reductase B;... 91 4e-17 UniRef50_Q568D7 Cluster: Zgc:110366; n=7; Euteleostomi|Rep: Zgc:... 91 5e-17 UniRef50_Q17568 Cluster: Putative uncharacterized protein; n=1; ... 90 8e-17 UniRef50_A3VRL4 Cluster: Putative uncharacterized protein; n=1; ... 89 1e-16 UniRef50_Q9A2X8 Cluster: Oxidoreductase, aldo/keto reductase fam... 89 1e-16 UniRef50_A1UEC5 Cluster: 2,5-didehydrogluconate reductase; n=20;... 89 1e-16 UniRef50_Q5UX52 Cluster: Oxidoreductase aldo/keto reductase fami... 89 1e-16 UniRef50_P47137 Cluster: Probable oxidoreductase YJR096W; n=8; S... 89 1e-16 UniRef50_Q5BLA6 Cluster: Zgc:110782; n=2; Danio rerio|Rep: Zgc:1... 88 3e-16 UniRef50_Q235V6 Cluster: Oxidoreductase, aldo/keto reductase fam... 88 3e-16 UniRef50_Q2U219 Cluster: Aldo/keto reductase family proteins; n=... 88 3e-16 UniRef50_UPI00006CA3CB Cluster: oxidoreductase, aldo/keto reduct... 88 3e-16 UniRef50_Q043M4 Cluster: Aldo/keto reductase of diketogulonate r... 88 3e-16 UniRef50_Q5KD52 Cluster: Oxidoreductase, putative; n=1; Filobasi... 88 3e-16 UniRef50_Q9X265 Cluster: Oxidoreductase, aldo/keto reductase fam... 87 5e-16 UniRef50_Q572D2 Cluster: Aldo-keto reductase, putative; n=1; Phy... 87 5e-16 UniRef50_Q18483 Cluster: Putative uncharacterized protein; n=2; ... 87 5e-16 UniRef50_A0AWM8 Cluster: Aldo/keto reductase; n=4; Actinomycetal... 87 6e-16 UniRef50_UPI00005A2CCB Cluster: PREDICTED: similar to Aldose red... 87 8e-16 UniRef50_Q6F7K7 Cluster: 2,5-diketo-D-gluconate reductase; n=20;... 87 8e-16 UniRef50_A5VK30 Cluster: 2,5-didehydrogluconate reductase; n=2; ... 87 8e-16 UniRef50_UPI0000DB6EE9 Cluster: PREDICTED: similar to C35D10.6; ... 86 1e-15 UniRef50_A7ALH6 Cluster: Putative uncharacterized protein; n=1; ... 86 1e-15 UniRef50_Q1Q8W8 Cluster: Aldo/keto reductase; n=1; Psychrobacter... 86 1e-15 UniRef50_Q0SFM4 Cluster: Probable 2,5-didehydrogluconate reducta... 86 1e-15 UniRef50_A5ZYE6 Cluster: Putative uncharacterized protein; n=1; ... 86 1e-15 UniRef50_A4YQ04 Cluster: 2,5-diketo-D-gluconate reductase B; n=1... 86 1e-15 UniRef50_Q11BF8 Cluster: Aldo/keto reductase; n=12; Bacteria|Rep... 85 2e-15 UniRef50_Q7VHE1 Cluster: Putative uncharacterized protein; n=1; ... 85 2e-15 UniRef50_Q927P9 Cluster: Lin2739 protein; n=12; Bacteria|Rep: Li... 85 3e-15 UniRef50_P91997 Cluster: Putative uncharacterized protein; n=4; ... 84 4e-15 UniRef50_Q5XJM7 Cluster: Zgc:101765; n=5; Eumetazoa|Rep: Zgc:101... 84 6e-15 UniRef50_Q927E1 Cluster: Lin2848 protein; n=13; Listeria|Rep: Li... 83 1e-14 UniRef50_Q8EVT8 Cluster: Oxidoreductase-aldo/keto reductase fami... 83 1e-14 UniRef50_A3WP89 Cluster: Aldo/keto reductase; n=1; Idiomarina ba... 83 1e-14 UniRef50_A2RMU6 Cluster: Oxidoreductase, aldo/keto reductase fam... 83 1e-14 UniRef50_UPI000155CAC7 Cluster: PREDICTED: hypothetical protein;... 83 1e-14 UniRef50_A2QB88 Cluster: Contig An01c0460, complete genome. prec... 83 1e-14 UniRef50_Q8Y463 Cluster: Lmo2592 protein; n=40; Bacteria|Rep: Lm... 82 2e-14 UniRef50_Q8G7K9 Cluster: Dehydrogenase or reductase protein; n=4... 82 2e-14 UniRef50_P91021 Cluster: Putative uncharacterized protein; n=1; ... 82 2e-14 UniRef50_Q11DV1 Cluster: Aldo/keto reductase; n=10; Alphaproteob... 82 2e-14 UniRef50_Q5V663 Cluster: Aldehyde reductase; n=6; Halobacteriace... 82 2e-14 UniRef50_A7D6Q0 Cluster: Aldo/keto reductase; n=1; Halorubrum la... 82 2e-14 UniRef50_UPI0000D56CE5 Cluster: PREDICTED: similar to CG6084-PA,... 81 3e-14 UniRef50_A6VNW9 Cluster: Aldo/keto reductase precursor; n=1; Act... 81 3e-14 UniRef50_Q8EVS8 Cluster: Oxidoreductase; n=1; Mycoplasma penetra... 81 4e-14 UniRef50_Q8EUH6 Cluster: Oxidoreductase; n=1; Mycoplasma penetra... 81 4e-14 UniRef50_A3JU52 Cluster: 2,5-diketo-D-gluconic acid reductase A;... 81 4e-14 UniRef50_A0L1A2 Cluster: Aldo/keto reductase; n=8; Gammaproteoba... 81 4e-14 UniRef50_A7RRF6 Cluster: Predicted protein; n=2; Nematostella ve... 81 4e-14 UniRef50_Q5FK99 Cluster: Oxidoreductase aldo-keto reductase fami... 81 5e-14 UniRef50_Q1M4Z6 Cluster: Putative aldo-keto reductase/oxidase; n... 80 7e-14 UniRef50_Q54NR2 Cluster: Aldo-keto reductase; n=3; Dictyostelium... 80 9e-14 UniRef50_Q6CEJ0 Cluster: Yarrowia lipolytica chromosome B of str... 80 9e-14 UniRef50_Q4WUF7 Cluster: Aldo-keto reductase, putative; n=3; Pez... 80 9e-14 UniRef50_Q4WP69 Cluster: Aldehyde reductase, putative; n=1; Aspe... 79 1e-13 UniRef50_A5BF24 Cluster: Putative uncharacterized protein; n=1; ... 79 2e-13 UniRef50_Q4DJ59 Cluster: Aldo/keto reductase, putative; n=2; Try... 79 2e-13 UniRef50_P15339 Cluster: 2,5-diketo-D-gluconic acid reductase B;... 79 2e-13 UniRef50_A7BES9 Cluster: Putative uncharacterized protein; n=1; ... 78 3e-13 UniRef50_Q5K8C5 Cluster: Aldo-keto reductase, putative; n=1; Fil... 78 3e-13 UniRef50_Q5UYI9 Cluster: Oxidoreductase; n=1; Haloarcula marismo... 78 4e-13 UniRef50_Q5B5R6 Cluster: Putative uncharacterized protein; n=1; ... 77 8e-13 UniRef50_A7D761 Cluster: Aldo/keto reductase; n=2; Halobacteriac... 77 8e-13 UniRef50_Q6U5V3 Cluster: Putative uncharacterized protein; n=1; ... 76 1e-12 UniRef50_Q6WGK4 Cluster: Aldose reductase; n=1; Pristionchus pac... 76 1e-12 UniRef50_Q9C1X5 Cluster: Xylose and arabinose reductase; n=1; Sc... 76 1e-12 UniRef50_A6SI80 Cluster: Putative uncharacterized protein; n=1; ... 76 1e-12 UniRef50_Q5V6N9 Cluster: Alcohol dehydrogenase; n=2; Halobacteri... 76 1e-12 UniRef50_Q3CZS2 Cluster: Oxidoreductase, aldo/keto reductase fam... 75 3e-12 UniRef50_Q9HM42 Cluster: Alcohol dehydrogenase related protein; ... 75 3e-12 UniRef50_Q1DLF1 Cluster: Putative uncharacterized protein; n=1; ... 75 3e-12 UniRef50_A7SGW6 Cluster: Predicted protein; n=1; Nematostella ve... 74 4e-12 UniRef50_Q0CK00 Cluster: Predicted protein; n=1; Aspergillus ter... 74 4e-12 UniRef50_A5DRJ6 Cluster: Putative uncharacterized protein; n=4; ... 74 4e-12 UniRef50_Q5V398 Cluster: Oxidoreductase aldo/keto reductase fami... 74 4e-12 UniRef50_Q4PE96 Cluster: Putative uncharacterized protein; n=1; ... 74 6e-12 UniRef50_Q2H7A8 Cluster: Putative uncharacterized protein; n=1; ... 73 1e-11 UniRef50_A6RMS0 Cluster: Putative uncharacterized protein; n=1; ... 71 3e-11 UniRef50_A3T261 Cluster: Putative uncharacterized protein; n=1; ... 71 4e-11 UniRef50_Q9P734 Cluster: Related to 2, 5-diketo-D-gluconic acid ... 71 4e-11 UniRef50_A1CAM7 Cluster: Aldo-keto reductase, putative; n=9; Dik... 71 4e-11 UniRef50_Q09632 Cluster: Probable oxidoreductase ZK1290.5; n=2; ... 71 6e-11 UniRef50_Q68A33 Cluster: Aldo-keto reductase 1a; n=1; Ciona inte... 70 1e-10 UniRef50_Q61U89 Cluster: Putative uncharacterized protein CBG054... 69 1e-10 UniRef50_Q59Z55 Cluster: Potential aldo/keto reductase; n=6; Sac... 69 1e-10 UniRef50_Q5KKZ8 Cluster: Aldo-keto reductase, putative; n=2; Fil... 69 2e-10 UniRef50_A4R217 Cluster: Putative uncharacterized protein; n=1; ... 69 2e-10 UniRef50_Q03U37 Cluster: Aldo/keto reductase of diketogulonate r... 68 3e-10 UniRef50_O14088 Cluster: Xylose and arabinose reductase; n=1; Sc... 68 3e-10 UniRef50_Q9P6D3 Cluster: Related to aldo-keto reductase YPR1; n=... 68 4e-10 UniRef50_Q4Q973 Cluster: Aldo/keto reductase, putative; n=3; Lei... 67 5e-10 UniRef50_Q0DHN0 Cluster: Os05g0456200 protein; n=2; Oryza sativa... 67 7e-10 UniRef50_A5BYJ4 Cluster: Putative uncharacterized protein; n=1; ... 67 7e-10 UniRef50_Q00XM4 Cluster: Aldo/keto reductase family proteins; n=... 66 9e-10 UniRef50_Q7M4N1 Cluster: Dihydrodiol dehydrogenase DD2; n=2; Hom... 66 9e-10 UniRef50_A7D7K7 Cluster: Aldo/keto reductase; n=1; Halorubrum la... 66 9e-10 UniRef50_Q5NLW3 Cluster: Putative oxidoreductase; n=1; Zymomonas... 66 1e-09 UniRef50_Q21274 Cluster: Putative uncharacterized protein; n=1; ... 66 2e-09 UniRef50_A7EW94 Cluster: Putative uncharacterized protein; n=1; ... 66 2e-09 UniRef50_Q2CAL9 Cluster: 2,5-didehydrogluconate reductase; n=2; ... 65 2e-09 UniRef50_Q6L139 Cluster: 2,5-diketo-D-gluconic acid reductase; n... 65 2e-09 UniRef50_Q979I4 Cluster: Aldo / keto reductase; n=3; Archaea|Rep... 65 3e-09 UniRef50_A6PR52 Cluster: Aldo/keto reductase; n=1; Victivallis v... 64 4e-09 UniRef50_Q4P1G1 Cluster: Putative uncharacterized protein; n=1; ... 64 4e-09 UniRef50_A7LSN6 Cluster: Putative uncharacterized protein; n=3; ... 64 5e-09 UniRef50_Q2BBN7 Cluster: YvgN; n=1; Bacillus sp. NRRL B-14911|Re... 64 6e-09 UniRef50_Q16CS5 Cluster: 2,5-diketo-D-gluconic acid reductase B,... 64 6e-09 UniRef50_A1RB46 Cluster: 2,5-diketo-D-gluconate reductase; n=1; ... 64 6e-09 UniRef50_Q76L37 Cluster: Conjugated polyketone reductase C1; n=3... 64 6e-09 UniRef50_Q6CWB9 Cluster: Similarities with sp|Q12458 Saccharomyc... 64 6e-09 UniRef50_A7TLC4 Cluster: Putative uncharacterized protein; n=1; ... 64 6e-09 UniRef50_A3H9Y8 Cluster: Aldo/keto reductase; n=2; Caldivirga ma... 64 6e-09 UniRef50_A7D6I8 Cluster: Aldo/keto reductase; n=1; Halorubrum la... 62 1e-08 UniRef50_Q14LA8 Cluster: Putative aldo/keto reductase oxidoreduc... 62 2e-08 UniRef50_Q4WI64 Cluster: Aldehyde reductase, putative; n=22; Pez... 62 2e-08 UniRef50_UPI0001556575 Cluster: PREDICTED: similar to Aldo-keto ... 62 3e-08 UniRef50_A6QVW8 Cluster: Predicted protein; n=1; Ajellomyces cap... 62 3e-08 UniRef50_Q97UV9 Cluster: Oxidoreductase; n=1; Sulfolobus solfata... 62 3e-08 UniRef50_Q4JCC1 Cluster: 2,5-diketo-D-gluconic acid reductase A;... 61 3e-08 UniRef50_Q1PV10 Cluster: Putative uncharacterized protein; n=1; ... 61 4e-08 UniRef50_Q5KCN9 Cluster: Putative uncharacterized protein; n=1; ... 61 4e-08 UniRef50_Q5V1M9 Cluster: Oxidoreductase aldo/keto reductase fami... 61 4e-08 UniRef50_A6R5B4 Cluster: NAD(P)H-dependent D-xylose reductase; n... 60 6e-08 UniRef50_Q11B35 Cluster: Aldo/keto reductase; n=1; Mesorhizobium... 60 8e-08 UniRef50_A4IJ00 Cluster: LOC548351 protein; n=1; Xenopus tropica... 60 1e-07 UniRef50_A2WWZ1 Cluster: Putative uncharacterized protein; n=1; ... 59 1e-07 UniRef50_A2G4I3 Cluster: Oxidoreductase, aldo/keto reductase fam... 59 1e-07 UniRef50_Q75E75 Cluster: ABL209Cp; n=1; Eremothecium gossypii|Re... 59 1e-07 UniRef50_P76234 Cluster: Uncharacterized protein yeaE; n=39; Bac... 59 1e-07 UniRef50_UPI000023DF27 Cluster: hypothetical protein FG07276.1; ... 58 3e-07 UniRef50_Q0GU15 Cluster: ORF28; n=3; Bacteria|Rep: ORF28 - Lacto... 58 3e-07 UniRef50_Q97U17 Cluster: Oxidoreductase, aldo/keto reductase fam... 58 3e-07 UniRef50_Q5FHT2 Cluster: Aldehyde reductase; n=4; Lactobacillus|... 58 4e-07 UniRef50_UPI000038E317 Cluster: hypothetical protein Faci_030017... 56 1e-06 UniRef50_Q4Q5X1 Cluster: Aldehyde reductase, putative; n=75; cel... 56 1e-06 UniRef50_Q97V56 Cluster: Dehydrogenase; n=8; Thermoprotei|Rep: D... 56 2e-06 UniRef50_Q4WF80 Cluster: Glycerol dehydrogenase (GCY1), putative... 55 2e-06 UniRef50_Q64UK5 Cluster: Aldo/keto reductase family oxidoreducta... 55 3e-06 UniRef50_Q03BE0 Cluster: Aldo/keto reductase family enzyme; n=5;... 55 3e-06 UniRef50_Q76L36 Cluster: Conjugated polyketone reductase C2; n=1... 55 3e-06 UniRef50_A3LWP0 Cluster: Aldo/keto reductase; n=7; Saccharomycet... 55 3e-06 UniRef50_Q89RG2 Cluster: Aldo/keto reductase; n=11; Bacteria|Rep... 54 5e-06 UniRef50_Q660Z5 Cluster: Aldose reductase, putative; n=3; Borrel... 54 5e-06 UniRef50_Q9V2P1 Cluster: Myo-inositol degradation; n=5; Archaea|... 54 5e-06 UniRef50_A7RUA2 Cluster: Predicted protein; n=1; Nematostella ve... 54 7e-06 UniRef50_Q59ZT1 Cluster: Putative uncharacterized protein; n=1; ... 54 7e-06 UniRef50_Q55FL2 Cluster: Putative uncharacterized protein; n=1; ... 53 9e-06 UniRef50_A1S0T5 Cluster: Aldo/keto reductase; n=2; Thermoprotei|... 52 2e-05 UniRef50_Q07551 Cluster: NADPH-dependent alpha-keto amide reduct... 52 2e-05 UniRef50_Q8PN61 Cluster: Oxidoreductase; n=5; Proteobacteria|Rep... 52 3e-05 UniRef50_Q7NK63 Cluster: Gll1617 protein; n=1; Gloeobacter viola... 51 4e-05 UniRef50_A2FJN9 Cluster: Putative uncharacterized protein; n=4; ... 50 6e-05 UniRef50_UPI00005F9591 Cluster: COG0656: Aldo/keto reductases, r... 50 8e-05 UniRef50_Q55ML8 Cluster: Putative uncharacterized protein; n=2; ... 50 1e-04 UniRef50_Q64W37 Cluster: 2,5-diketo-D-gluconic acid reductase; n... 49 1e-04 UniRef50_A3DNU7 Cluster: Aldo/keto reductase; n=3; Desulfurococc... 49 2e-04 UniRef50_Q8YAN3 Cluster: Lmo0084 protein; n=11; Listeria monocyt... 48 3e-04 UniRef50_Q6L0T3 Cluster: Oxidoreductase; n=2; Thermoplasmatales|... 48 4e-04 UniRef50_Q18903 Cluster: Putative uncharacterized protein C56G3.... 47 6e-04 UniRef50_A6BIJ0 Cluster: Putative uncharacterized protein; n=1; ... 47 8e-04 UniRef50_UPI0000D9C1BD Cluster: PREDICTED: similar to aldo-keto ... 46 0.001 UniRef50_A0RWV1 Cluster: Oxidoreductase; n=4; Thermoprotei|Rep: ... 40 0.001 UniRef50_UPI00015BB020 Cluster: aldo/keto reductase; n=1; Ignico... 46 0.001 UniRef50_A5GMY9 Cluster: Aldo/keto reductase family protein; n=2... 46 0.001 UniRef50_Q2BBT9 Cluster: Probable oxidoreductase protein; n=2; B... 46 0.002 UniRef50_Q9USV2 Cluster: Xylose and arabinose reductase; n=2; Sc... 46 0.002 UniRef50_Q9X0R5 Cluster: Oxidoreductase, aldo/keto reductase fam... 45 0.002 UniRef50_A1ZPI5 Cluster: Oxidoreductase; n=1; Microscilla marina... 45 0.002 UniRef50_Q1IQ78 Cluster: Aldo/keto reductase; n=1; Acidobacteria... 45 0.003 UniRef50_Q1U6R9 Cluster: Aldo/keto reductase; n=25; Bacilli|Rep:... 44 0.004 UniRef50_Q03I00 Cluster: Aryl-alcohol dehydrogenase related enzy... 44 0.004 UniRef50_A6SUJ2 Cluster: Uncharacterized conserved protein; n=2;... 44 0.004 UniRef50_A6QXT4 Cluster: Predicted protein; n=1; Ajellomyces cap... 44 0.004 UniRef50_Q8DK16 Cluster: Tlr1054 protein; n=6; Cyanobacteria|Rep... 44 0.005 UniRef50_A2UBC7 Cluster: Aldo/keto reductase; n=3; cellular orga... 44 0.005 UniRef50_Q013C5 Cluster: Glycerol dehydrogenase, putative; n=2; ... 44 0.007 UniRef50_Q4HND9 Cluster: Oxidoreductase, aldo/keto reductase fam... 43 0.013 UniRef50_Q21EY6 Cluster: Aldo/keto reductase; n=1; Saccharophagu... 43 0.013 UniRef50_Q03UP2 Cluster: Aryl-alcohol dehydrogenase family enzym... 42 0.017 UniRef50_A7HEV1 Cluster: Aldo/keto reductase; n=13; Bacteria|Rep... 42 0.017 UniRef50_A0LHW7 Cluster: Aldo/keto reductase precursor; n=1; Syn... 42 0.017 UniRef50_A7PNT1 Cluster: Chromosome chr8 scaffold_23, whole geno... 42 0.017 UniRef50_Q5BC40 Cluster: Putative uncharacterized protein; n=1; ... 42 0.017 UniRef50_Q8ZU65 Cluster: Aldo-keto reductase, putative; n=4; The... 42 0.017 UniRef50_Q88SS2 Cluster: Oxidoreductase; n=13; Firmicutes|Rep: O... 42 0.022 UniRef50_Q11KU9 Cluster: Twin-arginine translocation pathway sig... 42 0.022 UniRef50_A0YSM3 Cluster: Probable oxidoreductase; n=1; Lyngbya s... 42 0.022 UniRef50_Q2NEM6 Cluster: Putative oxidoreductase; n=1; Methanosp... 42 0.022 UniRef50_A3H7G3 Cluster: Aldo/keto reductase; n=2; Caldivirga ma... 42 0.022 UniRef50_Q08P32 Cluster: Aldo/keto reductase; n=3; Proteobacteri... 42 0.029 UniRef50_A7HAM2 Cluster: Aldo/keto reductase; n=9; cellular orga... 42 0.029 UniRef50_A6W292 Cluster: Aldo/keto reductase; n=9; Bacteria|Rep:... 42 0.029 UniRef50_A4QYG8 Cluster: Putative uncharacterized protein; n=1; ... 42 0.029 UniRef50_Q1FHF4 Cluster: Aldo/keto reductase:4Fe-4S ferredoxin, ... 41 0.039 UniRef50_A6X3I0 Cluster: Aldo/keto reductase; n=3; Bacteria|Rep:... 41 0.039 UniRef50_A6LWU9 Cluster: Aldo/keto reductase; n=3; Clostridium|R... 41 0.039 UniRef50_A4M6J9 Cluster: Aldo/keto reductase; n=1; Petrotoga mob... 41 0.039 UniRef50_A0YC40 Cluster: Putative uncharacterized protein; n=1; ... 41 0.039 UniRef50_UPI0000447325 Cluster: PREDICTED: similar to aldo-keto ... 41 0.051 UniRef50_Q93KW0 Cluster: Putative oxidoreductase; n=1; Streptomy... 41 0.051 UniRef50_Q8PVL5 Cluster: Oxidoreductase, ALDO/KETO reductase fam... 41 0.051 UniRef50_Q6GIV4 Cluster: Aldo/keto reductase family protein; n=1... 40 0.068 UniRef50_Q01Z07 Cluster: Aldo/keto reductase; n=4; cellular orga... 40 0.068 UniRef50_A6AKU1 Cluster: Aldo/keto reductase; n=2; Gammaproteoba... 40 0.068 UniRef50_Q8EUX1 Cluster: Aldo/keto reductase family oxidoreducta... 40 0.089 UniRef50_Q03UP0 Cluster: Aryl-alcohol dehydrogenase family enzym... 40 0.089 UniRef50_A0QWF1 Cluster: Aldo/keto reductase; n=1; Mycobacterium... 40 0.089 UniRef50_Q9C2J8 Cluster: Related to D-xylose reductase II, III p... 40 0.089 UniRef50_P80874 Cluster: General stress protein 69; n=16; cellul... 40 0.089 UniRef50_UPI0000DAE567 Cluster: hypothetical protein Rgryl_01000... 40 0.12 UniRef50_Q82NW9 Cluster: Putative oxidoreductase; n=3; Streptomy... 40 0.12 UniRef50_Q2AI49 Cluster: Aldo/keto reductase; n=1; Halothermothr... 40 0.12 UniRef50_A0QHX8 Cluster: General stress protein 69; n=2; Mycobac... 40 0.12 UniRef50_A0LJ47 Cluster: Aldo/keto reductase; n=1; Syntrophobact... 40 0.12 UniRef50_Q88TP1 Cluster: Oxidoreductase; n=3; Bacteria|Rep: Oxid... 39 0.16 UniRef50_A7BLU0 Cluster: Aldo/keto reductase family; n=1; Beggia... 39 0.16 UniRef50_Q9YBV5 Cluster: Putative uncharacterized protein; n=1; ... 39 0.16 UniRef50_Q8UIN0 Cluster: Oxidoreductase; n=3; Alphaproteobacteri... 39 0.21 UniRef50_Q5ZTU6 Cluster: D-xylose reductase III; n=5; Legionella... 39 0.21 UniRef50_Q3A7S5 Cluster: Predicted oxidoreductases of the aldo/k... 39 0.21 UniRef50_A0Y7Y8 Cluster: Aldo/keto reductase; n=1; marine gamma ... 39 0.21 UniRef50_Q4TC86 Cluster: Chromosome undetermined SCAF7044, whole... 38 0.27 UniRef50_Q8Y5Q1 Cluster: Lmo2005 protein; n=34; cellular organis... 38 0.27 UniRef50_Q2J8X9 Cluster: Aldo/keto reductase; n=3; Frankia|Rep: ... 38 0.27 UniRef50_A1SGJ5 Cluster: Aldo/keto reductase precursor; n=1; Noc... 38 0.27 UniRef50_UPI000023DAA9 Cluster: hypothetical protein FG00321.1; ... 38 0.36 UniRef50_Q8EVP7 Cluster: Putative oxidoreductase; n=3; Bacteria|... 38 0.36 UniRef50_Q97UG6 Cluster: Oxidoreductase; n=5; Archaea|Rep: Oxido... 38 0.36 UniRef50_Q55493 Cluster: Auxin-induced protein; n=2; Bacteria|Re... 38 0.48 UniRef50_Q1VSU3 Cluster: Aryl-alcohol dehydrogenase; n=1; Psychr... 38 0.48 UniRef50_A7B5J6 Cluster: Putative uncharacterized protein; n=1; ... 38 0.48 UniRef50_Q2H7Q3 Cluster: Putative uncharacterized protein; n=1; ... 38 0.48 UniRef50_Q5V3K3 Cluster: Oxidoreductase aldo/keto reductase fami... 38 0.48 UniRef50_Q64UJ6 Cluster: Putative aldo/keto reductase; n=3; Bact... 37 0.63 UniRef50_Q11BU4 Cluster: Aldo/keto reductase; n=11; Proteobacter... 37 0.63 UniRef50_Q04TM6 Cluster: Aryl-alcohol dehydrogenase-related oxid... 37 0.63 UniRef50_A6WAE5 Cluster: Aldo/keto reductase; n=1; Kineococcus r... 37 0.63 UniRef50_A5Z5D1 Cluster: Putative uncharacterized protein; n=4; ... 37 0.63 UniRef50_Q2NGB6 Cluster: Predicted oxidoreductase; n=1; Methanos... 37 0.63 UniRef50_Q94A68 Cluster: Uncharacterized oxidoreductase At1g0669... 37 0.63 UniRef50_Q391C9 Cluster: Aldo/keto reductase; n=10; Proteobacter... 37 0.83 UniRef50_Q21F89 Cluster: Aldo/keto reductase; n=1; Saccharophagu... 37 0.83 UniRef50_Q2H1Q3 Cluster: Putative uncharacterized protein; n=1; ... 37 0.83 UniRef50_Q82JL9 Cluster: Putative oxidoreductase; n=2; Streptomy... 36 1.1 UniRef50_A6C2P2 Cluster: Oxidoreductase, aldo/keto reductase fam... 36 1.1 UniRef50_A5VEK4 Cluster: Aldo/keto reductase; n=5; Bacteria|Rep:... 36 1.1 UniRef50_A3EV07 Cluster: Putative oxidoreductase; n=1; Leptospir... 36 1.1 UniRef50_A1RA11 Cluster: Oxidoreductase, aldo/keto reductase fam... 36 1.1 UniRef50_Q386M7 Cluster: Putative uncharacterized protein; n=1; ... 36 1.1 UniRef50_Q8TTK4 Cluster: Aldo/keto reductase; n=28; cellular org... 36 1.1 UniRef50_P46905 Cluster: Uncharacterized oxidoreductase yccK; n=... 36 1.1 UniRef50_Q2JB77 Cluster: Aldo/keto reductase; n=1; Frankia sp. C... 36 1.5 UniRef50_Q3WEJ4 Cluster: Aldo/keto reductase; n=9; Bacteria|Rep:... 36 1.5 UniRef50_Q08NK7 Cluster: Aldo/keto reductase; n=1; Stigmatella a... 36 1.5 UniRef50_A1ZSV4 Cluster: Oxidoreductase, aldo/keto reductase fam... 36 1.5 UniRef50_O59826 Cluster: Potassium channel subunit; n=9; cellula... 36 1.5 UniRef50_Q97ZZ1 Cluster: Oxidoreductase; n=4; Sulfolobaceae|Rep:... 36 1.5 UniRef50_P49261 Cluster: Rho beta-crystallin; n=1; Lepidodactylu... 36 1.5 UniRef50_Q8DHB7 Cluster: Tlr2042 protein; n=16; Cyanobacteria|Re... 36 1.9 UniRef50_Q41CR8 Cluster: Aldo/keto reductase; n=1; Exiguobacteri... 36 1.9 UniRef50_Q016B0 Cluster: COG0667: Predicted oxidoreductases; n=4... 36 1.9 UniRef50_Q5KKC5 Cluster: Putative uncharacterized protein; n=2; ... 36 1.9 UniRef50_A6SJ74 Cluster: Putative uncharacterized protein; n=1; ... 36 1.9 UniRef50_A1GCG3 Cluster: Aldo/keto reductase; n=3; Bacteria|Rep:... 35 2.5 UniRef50_A0GAJ5 Cluster: Aldo/keto reductase precursor; n=9; Pro... 35 2.5 UniRef50_Q97UJ7 Cluster: Oxidoreductase; n=4; Archaea|Rep: Oxido... 35 2.5 UniRef50_Q837G5 Cluster: Oxidoreductase, aldo/keto reductase 2 f... 35 3.4 UniRef50_Q0SJ60 Cluster: Possible aldo/keto reductase; n=50; Bac... 35 3.4 UniRef50_Q4D2F6 Cluster: Putative uncharacterized protein; n=1; ... 35 3.4 UniRef50_A3LSR5 Cluster: D-threo-aldose 1-dehydrogenase; n=5; Sa... 35 3.4 UniRef50_UPI00015B403B Cluster: PREDICTED: similar to CG18547-PA... 34 4.4 UniRef50_Q034L5 Cluster: Aryl-alcohol dehydrogenase related enzy... 34 4.4 UniRef50_A6VX84 Cluster: Aldo/keto reductase; n=4; Gammaproteoba... 34 4.4 UniRef50_A5FGY2 Cluster: Aldo/keto reductase; n=5; Bacteria|Rep:... 34 4.4 UniRef50_A0K1H5 Cluster: Aldo/keto reductase; n=6; Actinomycetal... 34 4.4 UniRef50_P0A9T5 Cluster: Protein tas; n=88; Bacteria|Rep: Protei... 34 4.4 UniRef50_Q01102 Cluster: P-selectin precursor; n=26; Eutheria|Re... 34 4.4 UniRef50_Q4T380 Cluster: Chromosome 21 SCAF10109, whole genome s... 34 5.9 UniRef50_Q2SHV2 Cluster: Putative uncharacterized protein; n=1; ... 34 5.9 UniRef50_Q0BAM8 Cluster: Aldo/keto reductase; n=1; Burkholderia ... 34 5.9 UniRef50_Q0B0F0 Cluster: Oxidoreductase; n=1; Syntrophomonas wol... 34 5.9 UniRef50_Q096Q3 Cluster: Oxidoreductase, aldo reductase; n=1; St... 34 5.9 UniRef50_A5NUR1 Cluster: Aldo/keto reductase precursor; n=2; Alp... 34 5.9 UniRef50_A2SFD3 Cluster: Putative oxidoreductase protein; n=1; M... 34 5.9 UniRef50_Q0U5W4 Cluster: Putative uncharacterized protein; n=1; ... 34 5.9 UniRef50_A7D5V2 Cluster: Aldo/keto reductase; n=1; Halorubrum la... 34 5.9 UniRef50_A3H9H5 Cluster: Aldo/keto reductase; n=2; Archaea|Rep: ... 34 5.9 UniRef50_Q14722 Cluster: Voltage-gated potassium channel subunit... 34 5.9 UniRef50_Q986W6 Cluster: Mlr7180 protein; n=4; Alphaproteobacter... 33 7.8 UniRef50_Q97RL3 Cluster: Oxidoreductase, aldo/keto reductase fam... 33 7.8 UniRef50_Q8R6G2 Cluster: Oxidoreductase; n=1; Fusobacterium nucl... 33 7.8 >UniRef50_Q7PCV3 Cluster: ENSANGP00000031808; n=9; Endopterygota|Rep: ENSANGP00000031808 - Anopheles gambiae str. PEST Length = 316 Score = 229 bits (560), Expect = 8e-59 Identities = 106/159 (66%), Positives = 117/159 (73%), Gaps = 1/159 (0%) Frame = +1 Query: 118 IPVVTFNNGESIPVFGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITS 297 +P F NG SIP+FGLGTW S PG+V QAVKDAID+GYRHIDCA+VY NE EVGE I + Sbjct: 6 VPNAIFKNGNSIPMFGLGTWNSPPGQVAQAVKDAIDVGYRHIDCAHVYQNEHEVGEGIAA 65 Query: 298 KIKEGVVTREDLFITSKLWNTFHRPDLVXGXLQETLDNLNVQYLDLYLIHWPQAYKEDGS 477 KI EGVV REDLF+TSKLWNTFHRPDLV G + TL NL + YLDLYLIHWP Y+E Sbjct: 66 KIAEGVVKREDLFVTSKLWNTFHRPDLVEGACKTTLQNLKLDYLDLYLIHWPVGYQEGTE 125 Query: 478 LFPTXQSGK-IQFSDXDYVDXWKAMEPLXKEGLVXSIGV 591 LFP GK FSD DYVD W ME L GLV +IGV Sbjct: 126 LFPMGPDGKTFLFSDADYVDTWPEMEKLVDAGLVRNIGV 164 Score = 46.8 bits (106), Expect = 8e-04 Identities = 17/34 (50%), Positives = 24/34 (70%) Frame = +3 Query: 594 NFNSKQLERLLQXATVKPVVNQVECHPLPHQKXL 695 NFN+KQ++R+L A + P NQ+ECHP HQ + Sbjct: 166 NFNAKQVQRVLDVARIPPATNQIECHPYLHQSKI 199 >UniRef50_Q2LZ66 Cluster: GA19341-PA; n=2; Endopterygota|Rep: GA19341-PA - Drosophila pseudoobscura (Fruit fly) Length = 315 Score = 210 bits (513), Expect = 4e-53 Identities = 94/158 (59%), Positives = 117/158 (74%), Gaps = 1/158 (0%) Frame = +1 Query: 121 PVVTFNNGESIPVFGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSK 300 P ++G ++P+ GLGTW+S P V QAVKDAIDIGYRH DCA++YGNE VG AI K Sbjct: 4 PSFLLSSGRNMPMVGLGTWRSPPEVVAQAVKDAIDIGYRHFDCAHIYGNELHVGVAIREK 63 Query: 301 IKEGVVTREDLFITSKLWNTFHRPDLVXGXLQETLDNLNVQYLDLYLIHWPQAYKEDGSL 480 I+EG+VTR++LFITSKLWNTFH+P+LV + +L NL + YLDLYL+HWP AYK +L Sbjct: 64 IQEGLVTRDELFITSKLWNTFHKPELVRAACETSLRNLGIDYLDLYLMHWPMAYKSGDNL 123 Query: 481 FPT-XQSGKIQFSDXDYVDXWKAMEPLXKEGLVXSIGV 591 +PT +GK F D DY+D WKAME L GLV +IGV Sbjct: 124 YPTCPDTGKAVFEDIDYLDTWKAMEDLVDSGLVNAIGV 161 Score = 45.6 bits (103), Expect = 0.002 Identities = 20/34 (58%), Positives = 24/34 (70%) Frame = +3 Query: 594 NFNSKQLERLLQXATVKPVVNQVECHPLPHQKXL 695 NFN KQ+ RLL A +KPV+ Q+ECHP QK L Sbjct: 163 NFNEKQINRLLCLAKLKPVMLQIECHPYLRQKSL 196 >UniRef50_Q9VTL0 Cluster: CG6083-PA; n=4; Diptera|Rep: CG6083-PA - Drosophila melanogaster (Fruit fly) Length = 322 Score = 204 bits (498), Expect = 2e-51 Identities = 93/159 (58%), Positives = 118/159 (74%), Gaps = 2/159 (1%) Frame = +1 Query: 121 PVVTFNNGESIPVFGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSK 300 P +NG+++P+ GLGTW+S P VTQAVKDAIDIGYRH DCA++YGNE +VG A+ K Sbjct: 4 PNFLLSNGKNMPMLGLGTWRSPPEVVTQAVKDAIDIGYRHFDCAHIYGNEAQVGAALREK 63 Query: 301 IKEGVVTREDLFITSKLWNTFHRPDLVXGXLQETLDNLNVQYLDLYLIHWPQAYKE-DGS 477 + EGVVTR++LFITSKLWNT H+PDLV + ++ NL V+YL+LYL+HWP AYK + Sbjct: 64 MDEGVVTRDELFITSKLWNTHHKPDLVRPACETSIRNLGVKYLNLYLMHWPMAYKSGSDN 123 Query: 478 LFPT-XQSGKIQFSDXDYVDXWKAMEPLXKEGLVXSIGV 591 L+PT + K F D DYVD W+AME L EGL +IGV Sbjct: 124 LYPTCPDTNKAAFEDIDYVDTWRAMENLVDEGLCQAIGV 162 Score = 46.0 bits (104), Expect = 0.001 Identities = 20/34 (58%), Positives = 24/34 (70%) Frame = +3 Query: 594 NFNSKQLERLLQXATVKPVVNQVECHPLPHQKXL 695 NFN +Q+ RLL A +KPVV Q+ECHP QK L Sbjct: 164 NFNEQQMNRLLSVAKLKPVVLQIECHPYLSQKPL 197 >UniRef50_P45376 Cluster: Aldose reductase; n=21; Bilateria|Rep: Aldose reductase - Mus musculus (Mouse) Length = 316 Score = 201 bits (490), Expect = 2e-50 Identities = 93/152 (61%), Positives = 108/152 (71%) Frame = +1 Query: 136 NNGESIPVFGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIKEGV 315 NNG +P GLGTWKS PG+VT+AVK AID+GYRHIDCA VY NEKEVG A+ K+KE V Sbjct: 8 NNGTKMPTLGLGTWKSPPGQVTEAVKVAIDLGYRHIDCAQVYQNEKEVGVALQEKLKEQV 67 Query: 316 VTREDLFITSKLWNTFHRPDLVXGXLQETLDNLNVQYLDLYLIHWPQAYKEDGSLFPTXQ 495 V R+DLFI SKLW TFH +V G Q+TL +L + YLDLYLIHWP +K FP Sbjct: 68 VKRQDLFIVSKLWCTFHDKSMVKGAFQKTLSDLQLDYLDLYLIHWPTGFKPGPDYFPLDA 127 Query: 496 SGKIQFSDXDYVDXWKAMEPLXKEGLVXSIGV 591 SG + SD D+VD W AME L EGLV +IGV Sbjct: 128 SGNVIPSDTDFVDTWTAMEQLVDEGLVKTIGV 159 Score = 37.9 bits (84), Expect = 0.36 Identities = 18/36 (50%), Positives = 23/36 (63%), Gaps = 2/36 (5%) Frame = +3 Query: 594 NFNSKQLERLLQXATVK--PVVNQVECHPLPHQKXL 695 NFN Q+ER+L +K P VNQ+ECHP Q+ L Sbjct: 161 NFNPLQIERILNKPGLKYKPAVNQIECHPYLTQEKL 196 >UniRef50_P15121 Cluster: Aldose reductase; n=72; Eumetazoa|Rep: Aldose reductase - Homo sapiens (Human) Length = 316 Score = 197 bits (481), Expect = 3e-49 Identities = 89/152 (58%), Positives = 109/152 (71%) Frame = +1 Query: 136 NNGESIPVFGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIKEGV 315 NNG +P+ GLGTWKS PG+VT+AVK AID+GYRHIDCA+VY NE EVG AI K++E V Sbjct: 8 NNGAKMPILGLGTWKSPPGQVTEAVKVAIDVGYRHIDCAHVYQNENEVGVAIQEKLREQV 67 Query: 316 VTREDLFITSKLWNTFHRPDLVXGXLQETLDNLNVQYLDLYLIHWPQAYKEDGSLFPTXQ 495 V RE+LFI SKLW T+H LV G Q+TL +L + YLDLYLIHWP +K FP + Sbjct: 68 VKREELFIVSKLWCTYHEKGLVKGACQKTLSDLKLDYLDLYLIHWPTGFKPGKEFFPLDE 127 Query: 496 SGKIQFSDXDYVDXWKAMEPLXKEGLVXSIGV 591 SG + SD + +D W AME L EGLV +IG+ Sbjct: 128 SGNVVPSDTNILDTWAAMEELVDEGLVKAIGI 159 Score = 35.1 bits (77), Expect = 2.5 Identities = 17/36 (47%), Positives = 22/36 (61%), Gaps = 2/36 (5%) Frame = +3 Query: 594 NFNSKQLERLLQXATVK--PVVNQVECHPLPHQKXL 695 NFN Q+E +L +K P VNQ+ECHP Q+ L Sbjct: 161 NFNHLQVEMILNKPGLKYKPAVNQIECHPYLTQEKL 196 >UniRef50_UPI00015B56A2 Cluster: PREDICTED: similar to GA10458-PA; n=2; Nasonia vitripennis|Rep: PREDICTED: similar to GA10458-PA - Nasonia vitripennis Length = 569 Score = 192 bits (467), Expect = 1e-47 Identities = 81/158 (51%), Positives = 114/158 (72%) Frame = +1 Query: 118 IPVVTFNNGESIPVFGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITS 297 +P VTFN+G +P+ GLGT+ SKPGEV +AVK AI++GYRH+D A+ Y NEKE+G AI Sbjct: 3 VPTVTFNDGYKMPMIGLGTFLSKPGEVAEAVKYAIEVGYRHVDTAFFYENEKEIGSAIRE 62 Query: 298 KIKEGVVTREDLFITSKLWNTFHRPDLVXGXLQETLDNLNVQYLDLYLIHWPQAYKEDGS 477 KI +G + RED+F+T+KLW H+ D V +++L+NL Y+DL+L+HWP A+K + Sbjct: 63 KINDGTIKREDIFVTTKLWCNSHKEDEVVPACKKSLENLGFDYIDLFLVHWPFAFKSGDA 122 Query: 478 LFPTXQSGKIQFSDXDYVDXWKAMEPLXKEGLVXSIGV 591 L P +GKI+FSD DY++ WK ME ++GL SIG+ Sbjct: 123 LTPRDAAGKIEFSDTDYLETWKGMEECKRQGLARSIGL 160 Score = 118 bits (283), Expect = 3e-25 Identities = 58/121 (47%), Positives = 77/121 (63%), Gaps = 1/121 (0%) Frame = +1 Query: 232 YRHIDCAYVYGNEKEVGEAITSKIKEGVVTREDLFITSKLWNTFHRPDLVXGXLQETLDN 411 YRHID AY+Y NEK +G AI KIK+G V REDLF+T+KL H+ V +++L++ Sbjct: 301 YRHIDTAYLYDNEKYIGNAIREKIKDGTVKREDLFVTTKLSYYAHKESEVVPACKQSLND 360 Query: 412 LNVQYLDLYLIHWP-QAYKEDGSLFPTXQSGKIQFSDXDYVDXWKAMEPLXKEGLVXSIG 588 L + Y+DLYLIHWP + Y SGK+ SD DY++ WK ME ++GL SIG Sbjct: 361 LGLDYIDLYLIHWPIRRYFRHNK----NASGKLLLSDTDYLETWKGMEECKRQGLARSIG 416 Query: 589 V 591 V Sbjct: 417 V 417 Score = 38.7 bits (86), Expect = 0.21 Identities = 19/34 (55%), Positives = 24/34 (70%) Frame = +3 Query: 594 NFNSKQLERLLQXATVKPVVNQVECHPLPHQKXL 695 NFNS+Q+ RLL+ A +KPV NQVE +QK L Sbjct: 419 NFNSEQITRLLEAAKIKPVNNQVEVSLKLNQKAL 452 Score = 37.5 bits (83), Expect = 0.48 Identities = 19/34 (55%), Positives = 23/34 (67%) Frame = +3 Query: 594 NFNSKQLERLLQXATVKPVVNQVECHPLPHQKXL 695 NFNS+Q+ RLL A +KPV NQVE +QK L Sbjct: 162 NFNSEQIARLLSSAKIKPVNNQVEVTMNLNQKPL 195 >UniRef50_Q9NAI5 Cluster: Putative uncharacterized protein; n=3; Caenorhabditis|Rep: Putative uncharacterized protein - Caenorhabditis elegans Length = 316 Score = 187 bits (455), Expect = 4e-46 Identities = 83/152 (54%), Positives = 105/152 (69%) Frame = +1 Query: 136 NNGESIPVFGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIKEGV 315 N+G SIP GLGTW+SKPGEV A+K A+ GYRHIDCA+VY N+KEVGEA+ + EG Sbjct: 8 NSGYSIPAIGLGTWQSKPGEVAAAIKTAVAAGYRHIDCAHVYQNQKEVGEALKEILDEGK 67 Query: 316 VTREDLFITSKLWNTFHRPDLVXGXLQETLDNLNVQYLDLYLIHWPQAYKEDGSLFPTXQ 495 V RE+LFITSK+WNTFH + L +L + Y+DL LIHWPQ Y E LFP + Sbjct: 68 VKREELFITSKVWNTFHSEAKAHENIDIILSDLQLSYVDLMLIHWPQGYAEGAELFPAGE 127 Query: 496 SGKIQFSDXDYVDXWKAMEPLXKEGLVXSIGV 591 +GK+++SD DY++ WKA E K G SIG+ Sbjct: 128 NGKMRYSDVDYLETWKAFEAAQKAGKCRSIGL 159 >UniRef50_Q8CI22 Cluster: 2310005E10Rik protein; n=30; Tetrapoda|Rep: 2310005E10Rik protein - Mus musculus (Mouse) Length = 316 Score = 186 bits (454), Expect = 5e-46 Identities = 87/155 (56%), Positives = 103/155 (66%) Frame = +1 Query: 127 VTFNNGESIPVFGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIK 306 VT G +P+ GLGTWKS P +V +AVK AID GYRHIDCAYVY NE EVGEAI KI+ Sbjct: 5 VTLLTGAKMPIVGLGTWKSPPAKVREAVKVAIDAGYRHIDCAYVYQNESEVGEAIQEKIQ 64 Query: 307 EGVVTREDLFITSKLWNTFHRPDLVXGXLQETLDNLNVQYLDLYLIHWPQAYKEDGSLFP 486 E V REDLFI SKLW+TF LV Q TL +L + YLDLYLIHWPQ ++ P Sbjct: 65 EKAVKREDLFIVSKLWSTFFEKSLVKKAFQNTLSDLKLDYLDLYLIHWPQGFQSGNVFLP 124 Query: 487 TXQSGKIQFSDXDYVDXWKAMEPLXKEGLVXSIGV 591 T G I S ++D W+AME L +GLV ++GV Sbjct: 125 TDDKGSILSSKYTFLDAWEAMEELVDQGLVKALGV 159 Score = 38.7 bits (86), Expect = 0.21 Identities = 20/36 (55%), Positives = 23/36 (63%), Gaps = 2/36 (5%) Frame = +3 Query: 594 NFNSKQLERLLQXATVK--PVVNQVECHPLPHQKXL 695 NFN Q+ERLL +K PV NQVECHP Q+ L Sbjct: 161 NFNHFQIERLLNKPGLKHKPVTNQVECHPYLTQEKL 196 >UniRef50_P14550 Cluster: Alcohol dehydrogenase [NADP+]; n=44; Bilateria|Rep: Alcohol dehydrogenase [NADP+] - Homo sapiens (Human) Length = 325 Score = 175 bits (426), Expect = 1e-42 Identities = 77/156 (49%), Positives = 108/156 (69%), Gaps = 1/156 (0%) Frame = +1 Query: 127 VTFNNGESIPVFGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIK 306 V + G+ +P+ GLGTWKS+PG+V AVK A+ +GYRHIDCA +YGNE E+GEA+ + Sbjct: 6 VLLHTGQKMPLIGLGTWKSEPGQVKAAVKYALSVGYRHIDCAAIYGNEPEIGEALKEDVG 65 Query: 307 EG-VVTREDLFITSKLWNTFHRPDLVXGXLQETLDNLNVQYLDLYLIHWPQAYKEDGSLF 483 G V RE+LF+TSKLWNT H P+ V L++TL +L ++YLDLYL+HWP A++ + F Sbjct: 66 PGKAVPREELFVTSKLWNTKHHPEDVEPALRKTLADLQLEYLDLYLMHWPYAFERGDNPF 125 Query: 484 PTXQSGKIQFSDXDYVDXWKAMEPLXKEGLVXSIGV 591 P G I + Y + WKA+E L +GLV ++G+ Sbjct: 126 PKNADGTICYDSTHYKETWKALEALVAKGLVQALGL 161 Score = 43.6 bits (98), Expect = 0.007 Identities = 19/42 (45%), Positives = 27/42 (64%) Frame = +3 Query: 594 NFNSKQLERLLQXATVKPVVNQVECHPLPHQKXLXSSVRLAG 719 NFNS+Q++ +L A+V+P V QVECHP Q L + + G Sbjct: 163 NFNSRQIDDILSVASVRPAVLQVECHPYLAQNELIAHCQARG 204 >UniRef50_Q17DN0 Cluster: Aldo-keto reductase; n=5; Culicidae|Rep: Aldo-keto reductase - Aedes aegypti (Yellowfever mosquito) Length = 324 Score = 170 bits (413), Expect = 5e-41 Identities = 86/162 (53%), Positives = 106/162 (65%), Gaps = 4/162 (2%) Frame = +1 Query: 118 IPVVTFNNGESIPVFGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITS 297 IP V NNG +P GLGT SK E +AV AID G+RHID AY Y NE VG AI + Sbjct: 6 IPTVKLNNGLEMPAIGLGTSMSKGDECCKAVMTAIDEGFRHIDTAYNYRNEDVVGRAIRA 65 Query: 298 KIKEGVVTREDLFITSKLWNTFHRPDLVXGXLQETLDNLNVQYLDLYLIHWPQAYKEDG- 474 KI+EGVVTRE+LF+T+KLWNTFH PD V ++L++L + Y+DL+LIH P Y+ +G Sbjct: 66 KIEEGVVTREELFVTTKLWNTFHHPDHVPMAFGKSLEHLGLDYVDLFLIHMPFGYEFNGW 125 Query: 475 ---SLFPTXQSGKIQFSDXDYVDXWKAMEPLXKEGLVXSIGV 591 P +G + SD DYVD WKAME L + G V SIGV Sbjct: 126 DPEKRTPLDDNGNVLCSDDDYVDTWKAMEKLLESGRVHSIGV 167 Score = 44.8 bits (101), Expect = 0.003 Identities = 21/34 (61%), Positives = 24/34 (70%) Frame = +3 Query: 594 NFNSKQLERLLQXATVKPVVNQVECHPLPHQKXL 695 NFNS+QLER+L VKPV NQVEC +QK L Sbjct: 169 NFNSEQLERILANCRVKPVTNQVECSARINQKLL 202 >UniRef50_Q7QK25 Cluster: ENSANGP00000019775; n=2; Anopheles gambiae str. PEST|Rep: ENSANGP00000019775 - Anopheles gambiae str. PEST Length = 319 Score = 166 bits (404), Expect = 6e-40 Identities = 79/167 (47%), Positives = 110/167 (65%), Gaps = 5/167 (2%) Frame = +1 Query: 106 MAPKIPVVTFNNGESIPVFGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGE 285 M+ ++P V F+NG IPV G GT+ ++ G+ + VK AID+GYRHID A++Y NE E+G+ Sbjct: 1 MSTQVPTVRFSNGYEIPVLGYGTYLAQKGQCVELVKKAIDLGYRHIDTAFLYENEVEIGQ 60 Query: 286 AITSKIKEGVVTREDLFITSKLWNTFHRPDLVXGXLQETLDNLNVQYLDLYLIHWPQAYK 465 AI KI EGV+ RED+F+T+KLWNTFH P V + + D L++ Y+DL+L+H P + Sbjct: 61 AIRDKIAEGVIRREDVFVTTKLWNTFHDPQHVEEAFRRSFDMLDIGYIDLFLMHSPMGVQ 120 Query: 466 EDG----SLFPTXQSGKIQFSDXDYVDXWKAMEPLXKE-GLVXSIGV 591 G + P +G + FSD DYV+ WKAME L G V SIG+ Sbjct: 121 FSGYEYADMQPKDAAGNMLFSDVDYVETWKAMEKLVTAGGRVRSIGL 167 Score = 47.6 bits (108), Expect = 4e-04 Identities = 23/42 (54%), Positives = 30/42 (71%) Frame = +3 Query: 594 NFNSKQLERLLQXATVKPVVNQVECHPLPHQKXLXSSVRLAG 719 NFNS+Q+ER+LQ ATVKPV NQVE +P Q+ L + + G Sbjct: 169 NFNSEQIERILQIATVKPVNNQVEANPGYDQRKLIAFCQARG 210 >UniRef50_Q8K023 Cluster: Aldo-keto reductase family 1 member C18; n=72; Tetrapoda|Rep: Aldo-keto reductase family 1 member C18 - Mus musculus (Mouse) Length = 323 Score = 162 bits (394), Expect = 1e-38 Identities = 77/165 (46%), Positives = 107/165 (64%), Gaps = 3/165 (1%) Frame = +1 Query: 106 MAPKIPVVTFNNGESIPVFGLGTWKSKPG---EVTQAVKDAIDIGYRHIDCAYVYGNEKE 276 M KI + N+G SIPV G GT+ ++ + ++ K AID+G+ HIDC+++Y NE+E Sbjct: 1 MNSKIQKIELNDGHSIPVLGFGTYATEEHLKKKSMESTKIAIDVGFCHIDCSHLYQNEEE 60 Query: 277 VGEAITSKIKEGVVTREDLFITSKLWNTFHRPDLVXGXLQETLDNLNVQYLDLYLIHWPQ 456 +G+AI SKI++G V RED+F TSKLW+T HRP+LV L+ +L LN+ Y+DLYLIH+P Sbjct: 61 IGQAILSKIEDGTVKREDIFYTSKLWSTSHRPELVRPSLENSLRKLNLDYVDLYLIHFPV 120 Query: 457 AYKEDGSLFPTXQSGKIQFSDXDYVDXWKAMEPLXKEGLVXSIGV 591 + K L P + G + F D D W+AME GL SIGV Sbjct: 121 SLKPGNELLPKDEHGNLIFDTVDLCDTWEAMEKCKDAGLAKSIGV 165 Score = 35.1 bits (77), Expect = 2.5 Identities = 18/42 (42%), Positives = 25/42 (59%), Gaps = 2/42 (4%) Frame = +3 Query: 594 NFNSKQLERLLQXATVK--PVVNQVECHPLPHQKXLXSSVRL 713 NFN +QLE +L +K PV NQVECH +Q L + ++ Sbjct: 167 NFNRRQLEMILNKPGLKYKPVCNQVECHLYLNQSKLLAYCKM 208 >UniRef50_UPI00015B56A3 Cluster: PREDICTED: similar to aldo-keto reductase; n=1; Nasonia vitripennis|Rep: PREDICTED: similar to aldo-keto reductase - Nasonia vitripennis Length = 321 Score = 161 bits (392), Expect = 2e-38 Identities = 74/164 (45%), Positives = 101/164 (61%), Gaps = 2/164 (1%) Frame = +1 Query: 106 MAPKIPVVTFNNGESIPVFGLGTWK--SKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEV 279 M+PK+ +T ++G +PV GLGTW+ + P EV AVK AID GYRH DCA YGNE E+ Sbjct: 1 MSPKVDEITLSDGNKVPVLGLGTWQGGNDPDEVENAVKLAIDAGYRHFDCASFYGNEAEI 60 Query: 280 GEAITSKIKEGVVTREDLFITSKLWNTFHRPDLVXGXLQETLDNLNVQYLDLYLIHWPQA 459 G+AI KI +GVV REDLF+ +K+WN + +LV + +L L + Y+DLYL+HWP + Sbjct: 61 GKAIQEKIDQGVVKREDLFVVTKVWNDERKQELVVAACKRSLKKLGLGYIDLYLVHWPFS 120 Query: 460 YKEDGSLFPTXQSGKIQFSDXDYVDXWKAMEPLXKEGLVXSIGV 591 Y + + DY++ W+ ME K GL SIGV Sbjct: 121 YPILYQYIVLPTYNAVTLDEVDYIETWRGMEECIKLGLTRSIGV 164 Score = 44.8 bits (101), Expect = 0.003 Identities = 20/34 (58%), Positives = 27/34 (79%) Frame = +3 Query: 594 NFNSKQLERLLQXATVKPVVNQVECHPLPHQKXL 695 NFNS+QL RLL+ A++KPV+NQ+E H +QK L Sbjct: 166 NFNSQQLTRLLESASIKPVMNQIELHINLNQKKL 199 >UniRef50_A5KSS3 Cluster: Aldehyde reductase; n=1; candidate division TM7 genomosp. GTL1|Rep: Aldehyde reductase - candidate division TM7 genomosp. GTL1 Length = 299 Score = 161 bits (392), Expect = 2e-38 Identities = 76/155 (49%), Positives = 100/155 (64%) Frame = +1 Query: 127 VTFNNGESIPVFGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIK 306 +T N +++P+ G GTW+ G V+ AI GYRHIDCA +YGNEKEVGE I I Sbjct: 4 LTLRNKQTLPLLGYGTWELPTGTTADLVETAIKAGYRHIDCAMIYGNEKEVGEGIRRTID 63 Query: 307 EGVVTREDLFITSKLWNTFHRPDLVXGXLQETLDNLNVQYLDLYLIHWPQAYKEDGSLFP 486 +GVV REDLF+TSKLWNT H V ++TL++L + YLDLYLIHW A++ +L P Sbjct: 64 QGVVKREDLFVTSKLWNTDHAQVDVGVACRKTLNDLGLDYLDLYLIHWGVAFEHGDNLEP 123 Query: 487 TXQSGKIQFSDXDYVDXWKAMEPLXKEGLVXSIGV 591 G +FS + W+AME L ++GLV S+GV Sbjct: 124 LDDDGVAKFSFISMKETWQAMEELVEQGLVKSMGV 158 >UniRef50_Q2S340 Cluster: Aldehyde reductase; n=10; Bacteria|Rep: Aldehyde reductase - Salinibacter ruber (strain DSM 13855) Length = 321 Score = 160 bits (388), Expect = 5e-38 Identities = 73/155 (47%), Positives = 99/155 (63%) Frame = +1 Query: 127 VTFNNGESIPVFGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIK 306 ++F NG+ +P+ GLGTWKS PGEV +AV A++ GYRH+DCA +Y NE EVG A++ Sbjct: 4 ISFENGDEMPMIGLGTWKSPPGEVYEAVTTALEAGYRHVDCAPIYKNETEVGAALSDSFD 63 Query: 307 EGVVTREDLFITSKLWNTFHRPDLVXGXLQETLDNLNVQYLDLYLIHWPQAYKEDGSLFP 486 G + R+D+++TSKLWN H PD V L++TL +L + LDLYLIHWP A + + FP Sbjct: 64 AGGIRRDDVWVTSKLWNNAHHPDDVRPALEQTLSDLRLDALDLYLIHWPVALQPEVD-FP 122 Query: 487 TXQSGKIQFSDXDYVDXWKAMEPLXKEGLVXSIGV 591 + + W AME L K+GLV IGV Sbjct: 123 ESPDDFVSPEAVPLTETWAAMEALKKDGLVRHIGV 157 >UniRef50_Q0VGY1 Cluster: 3-alpha-hydroxysteroid dehydrogenase; n=13; Tetrapoda|Rep: 3-alpha-hydroxysteroid dehydrogenase - Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) Length = 324 Score = 159 bits (387), Expect = 7e-38 Identities = 74/158 (46%), Positives = 101/158 (63%), Gaps = 3/158 (1%) Frame = +1 Query: 127 VTFNNGESIPVFGLGTW---KSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITS 297 V N+G +PV G GT+ K + K AID+GYRHIDCA++YGNE+EVG AI + Sbjct: 9 VELNDGHKMPVIGFGTYAPPKFPKSLAEEGTKVAIDVGYRHIDCAFLYGNEEEVGRAIRA 68 Query: 298 KIKEGVVTREDLFITSKLWNTFHRPDLVXGXLQETLDNLNVQYLDLYLIHWPQAYKEDGS 477 KI +G V RED+F T KLW+T H P+ V L+++L +L + Y+DL++IH P +K Sbjct: 69 KIADGTVKREDVFYTGKLWSTSHTPERVRPALEKSLKDLQLDYMDLFIIHMPMEFKPGDD 128 Query: 478 LFPTXQSGKIQFSDXDYVDXWKAMEPLXKEGLVXSIGV 591 LFP ++GK + + D D WKA+E GLV SIGV Sbjct: 129 LFPADENGKFIYHNTDLRDTWKALEKCKDAGLVRSIGV 166 Score = 35.9 bits (79), Expect = 1.5 Identities = 19/36 (52%), Positives = 22/36 (61%), Gaps = 2/36 (5%) Frame = +3 Query: 594 NFNSKQLERLLQXATVK--PVVNQVECHPLPHQKXL 695 NFN KQLE +L +K PV NQVECH +Q L Sbjct: 168 NFNHKQLELILNMPGLKYKPVCNQVECHVYLNQSKL 203 >UniRef50_UPI0000588153 Cluster: PREDICTED: hypothetical protein; n=1; Strongylocentrotus purpuratus|Rep: PREDICTED: hypothetical protein - Strongylocentrotus purpuratus Length = 333 Score = 159 bits (386), Expect = 9e-38 Identities = 71/157 (45%), Positives = 102/157 (64%), Gaps = 2/157 (1%) Frame = +1 Query: 127 VTFNNGESIPVFGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIK 306 VT +G ++P+ GLGTWK K EV A+ A+D GYRH DCA +YGNEKEVG A+ ++ Sbjct: 5 VTLPSGHAMPLVGLGTWKLKADEVAGAIGAAVDAGYRHFDCALIYGNEKEVGVALREAMQ 64 Query: 307 EGVVTREDLFITSKLWNTFHRPDLVXGXLQETLDNLNVQYLDLYLIHWPQAYKEDGS--L 480 + RED+FIT+K+WNTFH + V +L +L + Y+DLY++HWP ++ G + Sbjct: 65 RLGLKREDVFITTKVWNTFHAKEDVAECFNRSLTDLQLDYIDLYIMHWPLGFQNLGPTVM 124 Query: 481 FPTXQSGKIQFSDXDYVDXWKAMEPLXKEGLVXSIGV 591 FP ++G I +SD Y++ W AME L K G S+G+ Sbjct: 125 FPRTETGDIVYSDVHYLETWSAMEDLVKTGKCKSLGL 161 Score = 40.7 bits (91), Expect = 0.051 Identities = 21/39 (53%), Positives = 25/39 (64%) Frame = +3 Query: 594 NFNSKQLERLLQXATVKPVVNQVECHPLPHQKXLXSSVR 710 NFNSKQL+ +LQ +TV P V QVE HP Q L + R Sbjct: 163 NFNSKQLDDVLQHSTVPPSVLQVESHPFLPQVELLNFCR 201 >UniRef50_A7SIT3 Cluster: Predicted protein; n=1; Nematostella vectensis|Rep: Predicted protein - Nematostella vectensis Length = 323 Score = 157 bits (382), Expect = 3e-37 Identities = 80/162 (49%), Positives = 101/162 (62%) Frame = +1 Query: 106 MAPKIPVVTFNNGESIPVFGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGE 285 MA K N G SIP LGTW+S EV AV+ AI++GYRHIDCA +YGNE E+GE Sbjct: 1 MAMKQIFCKLNTGASIPAMALGTWQSSKEEVGNAVRLAIELGYRHIDCAEIYGNEGEIGE 60 Query: 286 AITSKIKEGVVTREDLFITSKLWNTFHRPDLVXGXLQETLDNLNVQYLDLYLIHWPQAYK 465 A++ + EG V RE+LF+TSKLW H PD V Q TL NL + YLDLYLIH P A+K Sbjct: 61 ALSEVLTEGKVKREELFVTSKLWCDSHHPDDVLPACQATLKNLQLDYLDLYLIHIPVAFK 120 Query: 466 EDGSLFPTXQSGKIQFSDXDYVDXWKAMEPLXKEGLVXSIGV 591 + L + G I ++ + W+AME L +GL +IGV Sbjct: 121 KGVRLPHSIAEGIIGYTPEGVQNTWQAMEGLVAKGLCKAIGV 162 Score = 38.3 bits (85), Expect = 0.27 Identities = 17/33 (51%), Positives = 24/33 (72%), Gaps = 1/33 (3%) Frame = +3 Query: 594 NFNSKQLERLLQXATVKPVVNQVECHP-LPHQK 689 NF+ K+L +LL+ A++ P NQVE HP LP +K Sbjct: 164 NFSVKRLNKLLETASIVPACNQVELHPYLPQEK 196 >UniRef50_P27800 Cluster: Aldehyde reductase 1; n=18; root|Rep: Aldehyde reductase 1 - Sporobolomyces salmonicolor Length = 323 Score = 157 bits (380), Expect = 5e-37 Identities = 81/163 (49%), Positives = 101/163 (61%), Gaps = 5/163 (3%) Frame = +1 Query: 118 IPVVTFNNGESIPVFGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITS 297 + T N G S+ + G GTW++ PGEV Q VK AI+ GYRH+D A VY N+ EVG AI Sbjct: 2 VGTTTLNTGASLELVGYGTWQAAPGEVGQGVKVAIETGYRHLDLAKVYSNQPEVGAAI-- 59 Query: 298 KIKEGVVTREDLFITSKLWNTFHRPDLVXGXLQETLDNLNVQYLDLYLIHWPQAYKEDG- 474 KE V REDLFITSKLWN HRP+ V L +TL L ++YLDLYLIHWP A+ +G Sbjct: 60 --KEAGVKREDLFITSKLWNNSHRPEQVEPALDDTLKELGLEYLDLYLIHWPVAFPPEGD 117 Query: 475 ---SLFPTXQSGKIQFS-DXDYVDXWKAMEPLXKEGLVXSIGV 591 +LFP +++ + VD WKAM L G V +IGV Sbjct: 118 ITQNLFPKANDKEVKLDLEVSLVDTWKAMVKLLDTGKVKAIGV 160 >UniRef50_Q54B70 Cluster: Aldehyde reductase; n=2; Dictyostelium discoideum|Rep: Aldehyde reductase - Dictyostelium discoideum AX4 Length = 297 Score = 155 bits (375), Expect = 2e-36 Identities = 80/158 (50%), Positives = 101/158 (63%), Gaps = 1/158 (0%) Frame = +1 Query: 121 PVVTFNNGESIPVFGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSK 300 P ++G IP+ G GTWK++ V +AV+ A+D GYRHIDCA VY NEKEVGEA T K Sbjct: 3 PSFKLSSGHKIPLVGFGTWKAETTLVGKAVEVALDAGYRHIDCAAVYLNEKEVGEAFTKK 62 Query: 301 IK-EGVVTREDLFITSKLWNTFHRPDLVXGXLQETLDNLNVQYLDLYLIHWPQAYKEDGS 477 E V RED+FITSKLWNTFH+ + V L+ TL +L +QYLDLYL+HWP A++ + Sbjct: 63 FTTEATVKREDVFITSKLWNTFHKKEHVRPALERTLSDLGLQYLDLYLVHWPVAFEYTSN 122 Query: 478 LFPTXQSGKIQFSDXDYVDXWKAMEPLXKEGLVXSIGV 591 T SG Q + W+ ME L GLV SIG+ Sbjct: 123 DIQT--SGSTQ-EFVSIRETWEEMEKLVDAGLVKSIGL 157 Score = 34.7 bits (76), Expect = 3.4 Identities = 16/34 (47%), Positives = 19/34 (55%) Frame = +3 Query: 594 NFNSKQLERLLQXATVKPVVNQVECHPLPHQKXL 695 NFN + L +L A +KP NQVE HP Q L Sbjct: 159 NFNVQGLMEVLSYARIKPAANQVELHPFLSQPEL 192 >UniRef50_Q96JD6-2 Cluster: Isoform 2 of Q96JD6 ; n=4; Catarrhini|Rep: Isoform 2 of Q96JD6 - Homo sapiens (Human) Length = 263 Score = 154 bits (374), Expect = 3e-36 Identities = 81/166 (48%), Positives = 100/166 (60%), Gaps = 19/166 (11%) Frame = +1 Query: 151 IPVFGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIKEGVVTRED 330 IP GL +WK+ PG+VT+AVK+AID GYRH DCAY Y NE+EVG I KIKEG V RED Sbjct: 4 IPAVGLSSWKASPGKVTEAVKEAIDAGYRHFDCAYFYHNEREVGAGIRCKIKEGAVRRED 63 Query: 331 LFITSKLWNTFHRPDLVXGXLQETLDNLNVQYLDLYLIHWPQAYKED--------GSL-- 480 LFI +KLW T H+ LV +++L L + YLDLYLIHWP +K L Sbjct: 64 LFIATKLWCTCHKKSLVETACRKSLKALKLNYLDLYLIHWPMGFKPPHPEWIMSCSELSF 123 Query: 481 ---------FPTXQSGKIQFSDXDYVDXWKAMEPLXKEGLVXSIGV 591 P +S + SD D++D W+AME L GLV +IGV Sbjct: 124 CLSHPRVQDLPLDESNMVIPSDTDFLDTWEAMEDLVITGLVKNIGV 169 >UniRef50_Q96JD6 Cluster: Aldo-keto reductase family 1 member C-like protein 2; n=37; Euteleostomi|Rep: Aldo-keto reductase family 1 member C-like protein 2 - Homo sapiens (Human) Length = 320 Score = 154 bits (374), Expect = 3e-36 Identities = 81/166 (48%), Positives = 100/166 (60%), Gaps = 19/166 (11%) Frame = +1 Query: 151 IPVFGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIKEGVVTRED 330 IP GL +WK+ PG+VT+AVK+AID GYRH DCAY Y NE+EVG I KIKEG V RED Sbjct: 4 IPAVGLSSWKASPGKVTEAVKEAIDAGYRHFDCAYFYHNEREVGAGIRCKIKEGAVRRED 63 Query: 331 LFITSKLWNTFHRPDLVXGXLQETLDNLNVQYLDLYLIHWPQAYKED--------GSL-- 480 LFI +KLW T H+ LV +++L L + YLDLYLIHWP +K L Sbjct: 64 LFIATKLWCTCHKKSLVETACRKSLKALKLNYLDLYLIHWPMGFKPPHPEWIMSCSELSF 123 Query: 481 ---------FPTXQSGKIQFSDXDYVDXWKAMEPLXKEGLVXSIGV 591 P +S + SD D++D W+AME L GLV +IGV Sbjct: 124 CLSHPRVQDLPLDESNMVIPSDTDFLDTWEAMEDLVITGLVKNIGV 169 Score = 42.3 bits (95), Expect = 0.017 Identities = 21/38 (55%), Positives = 25/38 (65%), Gaps = 2/38 (5%) Frame = +3 Query: 594 NFNSKQLERLLQXATV--KPVVNQVECHPLPHQKXLXS 701 NFN +QLERLL + KP+ NQ+ECHP QK L S Sbjct: 171 NFNHEQLERLLNKPGLRFKPLTNQIECHPYLTQKNLIS 208 >UniRef50_A2QBD7 Cluster: Catalytic activity: an alcohol + NADP(+) <=> an aldehyde + NADPH; n=4; Trichocomaceae|Rep: Catalytic activity: an alcohol + NADP(+) <=> an aldehyde + NADPH - Aspergillus niger Length = 323 Score = 154 bits (373), Expect = 3e-36 Identities = 77/154 (50%), Positives = 95/154 (61%) Frame = +1 Query: 130 TFNNGESIPVFGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIKE 309 T N G IP G GTW++KP EV AV+ A+ GYRHIDCA +Y NE EVG I K Sbjct: 8 TINTGAKIPAVGFGTWQAKPLEVENAVEVALREGYRHIDCAAIYRNETEVGNGIR---KS 64 Query: 310 GVVTREDLFITSKLWNTFHRPDLVXGXLQETLDNLNVQYLDLYLIHWPQAYKEDGSLFPT 489 GV RE++FIT KLWNT H P+ V L +TL +L V YLDLYL+HWP A+K FP Sbjct: 65 GV-PREEIFITGKLWNTKHAPEDVEPALDKTLQDLGVAYLDLYLMHWPCAFKGGDKWFPL 123 Query: 490 XQSGKIQFSDXDYVDXWKAMEPLXKEGLVXSIGV 591 G ++ DY+ ++AME L G V +IGV Sbjct: 124 NDDGVFDLANIDYITTYRAMEKLLATGKVRAIGV 157 Score = 37.9 bits (84), Expect = 0.36 Identities = 17/34 (50%), Positives = 21/34 (61%) Frame = +3 Query: 594 NFNSKQLERLLQXATVKPVVNQVECHPLPHQKXL 695 NFN ++LE LL +V P VNQ+E HP Q L Sbjct: 159 NFNIRRLEELLGQVSVVPAVNQIEAHPYLQQPDL 192 >UniRef50_A3U9Y0 Cluster: Aldehyde reductase; n=5; Bacteroidetes|Rep: Aldehyde reductase - Croceibacter atlanticus HTCC2559 Length = 316 Score = 153 bits (372), Expect = 5e-36 Identities = 71/153 (46%), Positives = 96/153 (62%) Frame = +1 Query: 133 FNNGESIPVFGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIKEG 312 F +G+SIP GLGTWKS P +V +AVK A++ GY+HIDCA Y NE VGEA + G Sbjct: 6 FRDGDSIPSIGLGTWKSDPEDVKKAVKIALENGYKHIDCAAAYDNEDAVGEAFKESFESG 65 Query: 313 VVTREDLFITSKLWNTFHRPDLVXGXLQETLDNLNVQYLDLYLIHWPQAYKEDGSLFPTX 492 V RED+F+TSKLWN H+ + V L++TL +LN+ YLDLYL+HWP A+K + FP Sbjct: 66 NVKREDIFVTSKLWNNAHKKEDVIPALKKTLKDLNLDYLDLYLMHWPVAFKPSVNGFPEK 125 Query: 493 QSGKIQFSDXDYVDXWKAMEPLXKEGLVXSIGV 591 + + + AM K+GL+ +GV Sbjct: 126 DEDYLSLEEAPLHETLNAMIEAKKQGLIKHVGV 158 >UniRef50_Q7JVH6 Cluster: LD24696p; n=2; Sophophora|Rep: LD24696p - Drosophila melanogaster (Fruit fly) Length = 311 Score = 153 bits (372), Expect = 5e-36 Identities = 72/159 (45%), Positives = 102/159 (64%), Gaps = 2/159 (1%) Frame = +1 Query: 121 PVVTFNNGESIPVFGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSK 300 P + NNG +P GLGTWKS + + + A+D+GYRH+D A+VY NE EVG+AI+ K Sbjct: 6 PTIRLNNGREMPTLGLGTWKSFESDAYHSTRHALDVGYRHLDTAFVYENEAEVGQAISEK 65 Query: 301 IKEGVVTREDLFITSKLWNTFHRPDLVXGXLQETLDNLNVQYLDLYLIHWP--QAYKEDG 474 I EGVVTRE++F+T+KL H P LV + +L NL ++Y+DLYL+H P Q + D Sbjct: 66 IAEGVVTREEVFVTTKLGGIHHDPALVERACRLSLSNLGLEYVDLYLMHMPVGQKFHNDS 125 Query: 475 SLFPTXQSGKIQFSDXDYVDXWKAMEPLXKEGLVXSIGV 591 ++ G ++ +D DY+D W+ ME L GL SIG+ Sbjct: 126 NV-----HGTLELTDVDYLDTWREMEKLVDLGLTRSIGL 159 Score = 45.2 bits (102), Expect = 0.002 Identities = 20/42 (47%), Positives = 26/42 (61%) Frame = +3 Query: 594 NFNSKQLERLLQXATVKPVVNQVECHPLPHQKXLXSSVRLAG 719 NFN+ Q ER+L ++PVVNQVECHP Q+ L + G Sbjct: 161 NFNAAQTERVLANCRIRPVVNQVECHPGFQQRQLREHAKRHG 202 >UniRef50_UPI000065D0BD Cluster: Homolog of Homo sapiens "AKR1B1 protein.; n=1; Takifugu rubripes|Rep: Homolog of Homo sapiens "AKR1B1 protein. - Takifugu rubripes Length = 330 Score = 151 bits (366), Expect = 2e-35 Identities = 81/182 (44%), Positives = 106/182 (58%), Gaps = 24/182 (13%) Frame = +1 Query: 118 IPVVTFNNGESIPVFGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITS 297 IP VT N G +PV GLGTWKS G T+AVK AI GYRHID AYVY NE EVG + + Sbjct: 2 IPSVTLNTGALMPVLGLGTWKSGKGVTTEAVKVAIGAGYRHIDTAYVYENETEVGAGVQA 61 Query: 298 KIKEGVVTREDLFITSKLWNTFHRPDLVXGXLQETLDNLNVQYLDLYLIHWPQ------- 456 I +GVV RE+LFI SKLW TFH P LV G ++TL +LN+ Y+DLYL+H+P Sbjct: 62 MIDQGVVKREELFIVSKLWCTFHTPSLVRGACEKTLSSLNLDYVDLYLMHFPMGALSATL 121 Query: 457 -----------AYKEDGSL------FPTXQSGKIQFSDXDYVDXWKAMEPLXKEGLVXSI 585 +++ L FP + ++ ++D W+AME L +GL +I Sbjct: 122 DLTSLTDVIPTVFRDFSPLQPGEDPFPLDEHNQLICDGTSFLDTWEAMEELVDDGLAKAI 181 Query: 586 GV 591 G+ Sbjct: 182 GI 183 Score = 35.9 bits (79), Expect = 1.5 Identities = 18/44 (40%), Positives = 24/44 (54%), Gaps = 2/44 (4%) Frame = +3 Query: 594 NFNSKQLERLLQXATVK--PVVNQVECHPLPHQKXLXSSVRLAG 719 NFN Q+E +L +K P NQ+ECHP +Q+ L R G Sbjct: 185 NFNKDQIEAVLNKPGLKHKPATNQIECHPHLNQEKLIHFCRSRG 228 >UniRef50_Q8VC28 Cluster: Aldo-keto reductase family 1 member C13; n=11; Theria|Rep: Aldo-keto reductase family 1 member C13 - Mus musculus (Mouse) Length = 323 Score = 151 bits (365), Expect = 3e-35 Identities = 74/165 (44%), Positives = 103/165 (62%), Gaps = 3/165 (1%) Frame = +1 Query: 106 MAPKIPVVTFNNGESIPVFGLGTWKSKPGEVTQAVKDA---IDIGYRHIDCAYVYGNEKE 276 M+ K V N+G IP G GT+K K +++++ A +D+GYRH+D AY Y E+E Sbjct: 1 MSSKQHCVKLNDGHLIPALGFGTYKPKEVPKSKSLEAACLALDVGYRHVDTAYAYQVEEE 60 Query: 277 VGEAITSKIKEGVVTREDLFITSKLWNTFHRPDLVXGXLQETLDNLNVQYLDLYLIHWPQ 456 +G+AI SKIK GVV REDLFIT+KLW T RP+LV L+++L L + Y+DLY++H+P Sbjct: 61 IGQAIQSKIKAGVVKREDLFITTKLWCTCFRPELVKPALEKSLKKLQLDYVDLYIMHYPV 120 Query: 457 AYKEDGSLFPTXQSGKIQFSDXDYVDXWKAMEPLXKEGLVXSIGV 591 K + FP + GK D+ D W+ +E GLV SIGV Sbjct: 121 PMKSGDNDFPVNEQGKSLLDTVDFCDTWERLEECKDAGLVKSIGV 165 Score = 37.9 bits (84), Expect = 0.36 Identities = 19/36 (52%), Positives = 24/36 (66%), Gaps = 2/36 (5%) Frame = +3 Query: 594 NFNSKQLERLLQXATVK--PVVNQVECHPLPHQKXL 695 NFN +QLER+L +K PV NQVECH +Q+ L Sbjct: 167 NFNHRQLERILNKPGLKYKPVCNQVECHLYLNQRKL 202 >UniRef50_Q96UH3 Cluster: Aldehyde reductase; n=13; Pezizomycotina|Rep: Aldehyde reductase - Coccidioides posadasii Length = 314 Score = 149 bits (361), Expect = 1e-34 Identities = 72/162 (44%), Positives = 95/162 (58%) Frame = +1 Query: 106 MAPKIPVVTFNNGESIPVFGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGE 285 MA + N GE IP G GTW+ + + AV A+ GYRHID A VYG EK +G Sbjct: 1 MASRHTTFRLNTGEDIPAIGFGTWQDENAQ-EDAVLTALSAGYRHIDTAAVYGTEKAIGR 59 Query: 286 AITSKIKEGVVTREDLFITSKLWNTFHRPDLVXGXLQETLDNLNVQYLDLYLIHWPQAYK 465 A+ ++R++LFITSKLWN HRP+ V + ++L NL + YLDLYL+HWP A+ Sbjct: 60 ALA----RSRLSRDELFITSKLWNNKHRPEDVEQAIDQSLKNLEIDYLDLYLMHWPAAFA 115 Query: 466 EDGSLFPTXQSGKIQFSDXDYVDXWKAMEPLXKEGLVXSIGV 591 +FP G + D DYVD +KAME L K G +IG+ Sbjct: 116 PGDDMFPKDSQGNSKTVDIDYVDTYKAMEKLVKSGKTKAIGI 157 >UniRef50_A4RQH8 Cluster: Predicted protein; n=2; Ostreococcus|Rep: Predicted protein - Ostreococcus lucimarinus CCE9901 Length = 337 Score = 149 bits (360), Expect = 1e-34 Identities = 76/162 (46%), Positives = 94/162 (58%) Frame = +1 Query: 106 MAPKIPVVTFNNGESIPVFGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGE 285 MAP +V NG IP GLGTWK++P EV AV+DA+ GY H+DCA Y NE EVGE Sbjct: 1 MAPSTILVNDANGLRIPRVGLGTWKARPNEVRDAVRDALGAGYAHVDCAAAYANESEVGE 60 Query: 286 AITSKIKEGVVTREDLFITSKLWNTFHRPDLVXGXLQETLDNLNVQYLDLYLIHWPQAYK 465 A+ + G RED+F+TSKLWN RP V L TL++L V YLDLYLIHWP A+K Sbjct: 61 ALREAFERGDAKREDVFVTSKLWNDRRRPRDVREALMTTLNDLGVGYLDLYLIHWPVAWK 120 Query: 466 EDGSLFPTXQSGKIQFSDXDYVDXWKAMEPLXKEGLVXSIGV 591 L P ++ + W +E +GLV IGV Sbjct: 121 RGTVLQPD--------AEASIAECWSELERCVADGLVRHIGV 154 >UniRef50_UPI0000E4A7CE Cluster: PREDICTED: similar to LOC553452 protein; n=6; Strongylocentrotus purpuratus|Rep: PREDICTED: similar to LOC553452 protein - Strongylocentrotus purpuratus Length = 321 Score = 148 bits (359), Expect = 2e-34 Identities = 74/163 (45%), Positives = 98/163 (60%), Gaps = 1/163 (0%) Frame = +1 Query: 106 MAPKIPVVTFNNGESIPVFGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGE 285 MA + G +P+ G GTW+ KP EV + ++ AID GYRHID A +YGNEK VG+ Sbjct: 1 MASSNTHIVLPGGRKLPLLGFGTWQIKPEEVGRVIETAIDCGYRHIDEASLYGNEKGVGD 60 Query: 286 AITSKIKEGVVTREDLFITSKLWNTFHRPDLVXGXLQETLDNLNVQYLDLYLIHWPQAYK 465 I +KI +G + REDLF+TSKLW T P V +++L +L + YLDL+LIH P + Sbjct: 61 GIKAKIDDGTIKREDLFVTSKLWVTDSHPSRVEPSCRQSLSDLGLAYLDLFLIHCPTSAV 120 Query: 466 EDGSLFPTXQSGKIQFSD-XDYVDXWKAMEPLXKEGLVXSIGV 591 FP +G D DYVD W+ ME L +GLV +IGV Sbjct: 121 GGKGPFPMDDNGLFIGDDTIDYVDTWRIMESLVDKGLVRAIGV 163 >UniRef50_Q7QVQ9 Cluster: GLP_302_44328_45269; n=1; Giardia lamblia ATCC 50803|Rep: GLP_302_44328_45269 - Giardia lamblia ATCC 50803 Length = 313 Score = 148 bits (359), Expect = 2e-34 Identities = 71/150 (47%), Positives = 93/150 (62%), Gaps = 4/150 (2%) Frame = +1 Query: 154 PVFGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIKEGV--VTRE 327 P G GTW++ P V AV+ A+ GYRHIDCAYVY NE+ +G A K+ + RE Sbjct: 5 PRLGFGTWQAPPEAVQTAVETALMTGYRHIDCAYVYQNEEAIGRAFGKIFKDASSGIKRE 64 Query: 328 DLFITSKLWNTFHRPDLVXGXLQETLDNLNVQYLDLYLIHWPQAY--KEDGSLFPTXQSG 501 D++ITSKLWN HRP+LV ++T+ +L V YLDL+L+HWP A+ + G LFP G Sbjct: 65 DVWITSKLWNYNHRPELVREQCKKTMSDLQVDYLDLFLVHWPLAFVRNDVGDLFPKDAEG 124 Query: 502 KIQFSDXDYVDXWKAMEPLXKEGLVXSIGV 591 + D W+AME L +EGLV IGV Sbjct: 125 RAMLEKVPLADTWRAMEQLVEEGLVKHIGV 154 >UniRef50_Q10494 Cluster: Probable oxidoreductase C26F1.07; n=2; Schizosaccharomyces pombe|Rep: Probable oxidoreductase C26F1.07 - Schizosaccharomyces pombe (Fission yeast) Length = 321 Score = 148 bits (358), Expect = 2e-34 Identities = 70/154 (45%), Positives = 94/154 (61%) Frame = +1 Query: 130 TFNNGESIPVFGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIKE 309 T +G IP GLGTW+S+P + AVK A+ GYRHID A +YGNE EVG+ I KE Sbjct: 17 TLADGSKIPGLGLGTWRSEPNQTKNAVKTALQYGYRHIDAAAIYGNEDEVGDGI----KE 72 Query: 310 GVVTREDLFITSKLWNTFHRPDLVXGXLQETLDNLNVQYLDLYLIHWPQAYKEDGSLFPT 489 V R+D+++TSKLW H P+ V L++TL +L + YLD YLIHWP ++K FP Sbjct: 73 SGVPRKDIWVTSKLWCNAHAPEAVPKALEKTLKDLKLDYLDEYLIHWPVSFKTGEDKFPK 132 Query: 490 XQSGKIQFSDXDYVDXWKAMEPLXKEGLVXSIGV 591 + G + + + WKAME L + G V IG+ Sbjct: 133 DKDGNLIYEKNPIEETWKAMEKLLETGKVRHIGL 166 Score = 39.5 bits (88), Expect = 0.12 Identities = 19/41 (46%), Positives = 26/41 (63%), Gaps = 1/41 (2%) Frame = +3 Query: 594 NFNSKQLERLLQXATVKPVVNQVECHP-LPHQKXLXSSVRL 713 NFN LER+L+ A VKP V+Q+E HP LP + + +L Sbjct: 168 NFNDTNLERILKVAKVKPAVHQMELHPFLPQTEFVEKHKKL 208 >UniRef50_Q2V420 Cluster: Uncharacterized protein At2g37770.1; n=1; Arabidopsis thaliana|Rep: Uncharacterized protein At2g37770.1 - Arabidopsis thaliana (Mouse-ear cress) Length = 283 Score = 147 bits (356), Expect = 4e-34 Identities = 77/162 (47%), Positives = 94/162 (58%) Frame = +1 Query: 106 MAPKIPVVTFNNGESIPVFGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGE 285 MA I N G P GLGTW++ PG V AV A+ IGYRHIDCA +YGNEKE+G Sbjct: 1 MANAITFFKLNTGAKFPSVGLGTWQASPGLVGDAVAAAVKIGYRHIDCAQIYGNEKEIGA 60 Query: 286 AITSKIKEGVVTREDLFITSKLWNTFHRPDLVXGXLQETLDNLNVQYLDLYLIHWPQAYK 465 + ++ VV REDLFITSKLW T H P V L TL +L ++Y+DLYLIHWP K Sbjct: 61 VLKKLFEDRVVKREDLFITSKLWCTDHDPQDVPEALNRTLKDLQLEYVDLYLIHWPARIK 120 Query: 466 EDGSLFPTXQSGKIQFSDXDYVDXWKAMEPLXKEGLVXSIGV 591 + GS+ ++ D WKAME L G +IGV Sbjct: 121 K-GSVGIKPEN----LLPVDIPSTWKAMEALYDSGKARAIGV 157 Score = 41.5 bits (93), Expect = 0.029 Identities = 20/42 (47%), Positives = 25/42 (59%) Frame = +3 Query: 594 NFNSKQLERLLQXATVKPVVNQVECHPLPHQKXLXSSVRLAG 719 NF++K+L LL+ A V P VNQVECHP Q L + G Sbjct: 159 NFSTKKLADLLELARVPPAVNQVECHPSWRQTKLQEFCKSKG 200 >UniRef50_Q0PGJ6 Cluster: Aldo-keto reductase; n=32; Magnoliophyta|Rep: Aldo-keto reductase - Arabidopsis thaliana (Mouse-ear cress) Length = 315 Score = 147 bits (356), Expect = 4e-34 Identities = 77/162 (47%), Positives = 94/162 (58%) Frame = +1 Query: 106 MAPKIPVVTFNNGESIPVFGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGE 285 MA I N G P GLGTW++ PG V AV A+ IGYRHIDCA +YGNEKE+G Sbjct: 1 MANAITFFKLNTGAKFPSVGLGTWQASPGLVGDAVAAAVKIGYRHIDCAQIYGNEKEIGA 60 Query: 286 AITSKIKEGVVTREDLFITSKLWNTFHRPDLVXGXLQETLDNLNVQYLDLYLIHWPQAYK 465 + ++ VV REDLFITSKLW T H P V L TL +L ++Y+DLYLIHWP K Sbjct: 61 VLKKLFEDRVVKREDLFITSKLWCTDHDPQDVPEALNRTLKDLQLEYVDLYLIHWPARIK 120 Query: 466 EDGSLFPTXQSGKIQFSDXDYVDXWKAMEPLXKEGLVXSIGV 591 + GS+ ++ D WKAME L G +IGV Sbjct: 121 K-GSVGIKPEN----LLPVDIPSTWKAMEALYDSGKARAIGV 157 Score = 41.5 bits (93), Expect = 0.029 Identities = 20/42 (47%), Positives = 25/42 (59%) Frame = +3 Query: 594 NFNSKQLERLLQXATVKPVVNQVECHPLPHQKXLXSSVRLAG 719 NF++K+L LL+ A V P VNQVECHP Q L + G Sbjct: 159 NFSTKKLADLLELARVPPAVNQVECHPSWRQTKLQEFCKSKG 200 >UniRef50_P51857 Cluster: 3-oxo-5-beta-steroid 4-dehydrogenase (EC 1.3.1.3) (Delta(4)-3- ketosteroid 5-beta-reductase); n=124; cellular organisms|Rep: 3-oxo-5-beta-steroid 4-dehydrogenase (EC 1.3.1.3) (Delta(4)-3- ketosteroid 5-beta-reductase) - Homo sapiens (Human) Length = 326 Score = 146 bits (354), Expect = 7e-34 Identities = 75/159 (47%), Positives = 98/159 (61%), Gaps = 4/159 (2%) Frame = +1 Query: 127 VTFNNGESIPVFGLGTW---KSKP-GEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAIT 294 + ++G SIP+ GLGT+ KS P G +VK AID GYRHID AY+Y NE EVGEAI Sbjct: 10 IPLSDGNSIPIIGLGTYSEPKSTPKGACATSVKVAIDTGYRHIDGAYIYQNEHEVGEAIR 69 Query: 295 SKIKEGVVTREDLFITSKLWNTFHRPDLVXGXLQETLDNLNVQYLDLYLIHWPQAYKEDG 474 KI EG V RED+F KLW T H P++V L+ TL L + Y+DLY+I P A+K Sbjct: 70 EKIAEGKVRREDIFYCGKLWATNHVPEMVRPTLERTLRVLQLDYVDLYIIEVPMAFKPGD 129 Query: 475 SLFPTXQSGKIQFSDXDYVDXWKAMEPLXKEGLVXSIGV 591 ++P ++GK + + W+AME GLV S+GV Sbjct: 130 EIYPRDENGKWLYHKSNLCATWEAMEACKDAGLVKSLGV 168 Score = 35.9 bits (79), Expect = 1.5 Identities = 17/29 (58%), Positives = 20/29 (68%), Gaps = 2/29 (6%) Frame = +3 Query: 594 NFNSKQLERLLQXATVK--PVVNQVECHP 674 NFN +QLE +L +K PV NQVECHP Sbjct: 170 NFNRRQLELILNKPGLKHKPVSNQVECHP 198 >UniRef50_Q5BKE9 Cluster: LOC594893 protein; n=5; Xenopus tropicalis|Rep: LOC594893 protein - Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) Length = 345 Score = 144 bits (348), Expect = 4e-33 Identities = 68/141 (48%), Positives = 89/141 (63%) Frame = +1 Query: 169 GTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIKEGVVTREDLFITSK 348 GT KS +V A K A+D+GYRH+D A++Y +E VG+A K +G + REDLF TSK Sbjct: 47 GTEKSFIDDVRVATKMALDLGYRHVDGAFLYSSETGVGQAFREKFADGTLKREDLFYTSK 106 Query: 349 LWNTFHRPDLVXGXLQETLDNLNVQYLDLYLIHWPQAYKEDGSLFPTXQSGKIQFSDXDY 528 LWNTFH+P LV L++TL L + Y+DLYLIH P ++K LFP + G F D Sbjct: 107 LWNTFHQPHLVRPALEKTLSFLQMDYVDLYLIHMPMSFKPAEELFPKNEDGTCAFDQPDL 166 Query: 529 VDXWKAMEPLXKEGLVXSIGV 591 + W+A+E GLV SIGV Sbjct: 167 LQTWQALEECRDAGLVKSIGV 187 Score = 39.5 bits (88), Expect = 0.12 Identities = 18/36 (50%), Positives = 24/36 (66%), Gaps = 2/36 (5%) Frame = +3 Query: 594 NFNSKQLERLLQXATVK--PVVNQVECHPLPHQKXL 695 NFN +QLE +L +K PV NQ+ECHP +QK + Sbjct: 189 NFNRRQLEMILNKPGLKYKPVCNQIECHPYLNQKQM 224 >UniRef50_Q0IBY6 Cluster: Alcohol dehydrogenase; n=2; Chroococcales|Rep: Alcohol dehydrogenase - Synechococcus sp. (strain CC9311) Length = 336 Score = 144 bits (348), Expect = 4e-33 Identities = 70/174 (40%), Positives = 103/174 (59%) Frame = +1 Query: 70 RSSQAAAKLINKMAPKIPVVTFNNGESIPVFGLGTWKSKPGEVTQAVKDAIDIGYRHIDC 249 R + I + P + + +NG+ +P+ GLGT KS+ +V ++V++AI IGYRHIDC Sbjct: 3 RDLSTSVNNIKDVIPTMQYASLSNGDRMPLLGLGTGKSESRQVYKSVREAIKIGYRHIDC 62 Query: 250 AYVYGNEKEVGEAITSKIKEGVVTREDLFITSKLWNTFHRPDLVXGXLQETLDNLNVQYL 429 A +YGNE+EVG+AI I+ +TR +L+ITSKLW+ H + V L ++L NL V YL Sbjct: 63 ASIYGNEEEVGDAIRDAIQNHEITRSELWITSKLWSNCHGKNHVEAALSQSLQNLGVDYL 122 Query: 430 DLYLIHWPQAYKEDGSLFPTXQSGKIQFSDXDYVDXWKAMEPLXKEGLVXSIGV 591 +LYLIHWP + + F + + + W+AME +GL IGV Sbjct: 123 NLYLIHWPVGIRPE-KTFAESVDDLLTPEESPISETWEAMESTRDKGLTKHIGV 175 Score = 35.5 bits (78), Expect = 1.9 Identities = 17/34 (50%), Positives = 21/34 (61%) Frame = +3 Query: 594 NFNSKQLERLLQXATVKPVVNQVECHPLPHQKXL 695 NF K+L++L+ KP VNQVE HPL Q L Sbjct: 177 NFTVKKLQQLVSHCKQKPEVNQVEHHPLLQQPTL 210 >UniRef50_A2R6Z3 Cluster: Catalytic activity: an alcohol + NADP(+) <=> an aldehyde + NADPH; n=9; Pezizomycotina|Rep: Catalytic activity: an alcohol + NADP(+) <=> an aldehyde + NADPH - Aspergillus niger Length = 345 Score = 142 bits (344), Expect = 1e-32 Identities = 73/154 (47%), Positives = 94/154 (61%), Gaps = 2/154 (1%) Frame = +1 Query: 136 NNGESIPVFGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIKEGV 315 N G +P GLGTW+SK EV AV A+ GYRHID A VYGNE+EVG+ ++ Sbjct: 10 NTGYDMPAVGLGTWQSKKDEVRDAVIAALKCGYRHIDAAAVYGNEQEVGDG----MRLSG 65 Query: 316 VTREDLFITSKLWNTFHRPDLVXGXLQETLDNLNVQYLDLYLIHWPQAYKEDGSLFP--T 489 V RE++F+TSKLWNT H P+ V + ++L +L YLDLYLIHWP A++ + Sbjct: 66 VPREEIFLTSKLWNTHHHPENVEEAVDKSLADLQTDYLDLYLIHWPVAFRYSTTTIQPVN 125 Query: 490 XQSGKIQFSDXDYVDXWKAMEPLXKEGLVXSIGV 591 Q+G I D D W AME L ++G V SIGV Sbjct: 126 EQTGLIDVVDVPIKDTWAAMEKLVEKGKVRSIGV 159 Score = 38.3 bits (85), Expect = 0.27 Identities = 15/34 (44%), Positives = 22/34 (64%) Frame = +3 Query: 594 NFNSKQLERLLQXATVKPVVNQVECHPLPHQKXL 695 NF +++E LL+ A + P VNQ+E HP Q+ L Sbjct: 161 NFTREKIEELLKTAKITPAVNQIEAHPFLQQRDL 194 >UniRef50_UPI0000498F1F Cluster: oxidoreductase, aldo/keto reductase family; n=2; Entamoeba histolytica HM-1:IMSS|Rep: oxidoreductase, aldo/keto reductase family - Entamoeba histolytica HM-1:IMSS Length = 305 Score = 140 bits (339), Expect = 5e-32 Identities = 75/154 (48%), Positives = 94/154 (61%) Frame = +1 Query: 130 TFNNGESIPVFGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIKE 309 T NNG IP GLGTW S GEV +AV+ AI GYRHIDCA YGNEKEVG+ I S I + Sbjct: 6 TLNNGYKIPKLGLGTWMSANGEVGKAVEIAIKNGYRHIDCAKAYGNEKEVGDGIKSAIAK 65 Query: 310 GVVTREDLFITSKLWNTFHRPDLVXGXLQETLDNLNVQYLDLYLIHWPQAYKEDGSLFPT 489 G V RE+LF+T+KLW+T + V E+L L ++YLDLY+IH P L Sbjct: 66 GYVKREELFVTTKLWSTDKHKEDVRPACLESLKKLQLEYLDLYIIHIP--------LTAD 117 Query: 490 XQSGKIQFSDXDYVDXWKAMEPLXKEGLVXSIGV 591 ++G+ + W+ ME L +EGLV SIGV Sbjct: 118 KKTGEFTEEIIPIEETWREMEKLVEEGLVKSIGV 151 Score = 34.7 bits (76), Expect = 3.4 Identities = 15/26 (57%), Positives = 18/26 (69%) Frame = +3 Query: 594 NFNSKQLERLLQXATVKPVVNQVECH 671 NFN K+LE LL A ++P VNQ E H Sbjct: 153 NFNIKKLEELLAIAKIQPAVNQFEFH 178 >UniRef50_A2QVE5 Cluster: Similarity: shows similarity to several dehydrogenases of different specificities; n=4; Pezizomycotina|Rep: Similarity: shows similarity to several dehydrogenases of different specificities - Aspergillus niger Length = 381 Score = 140 bits (338), Expect = 6e-32 Identities = 69/153 (45%), Positives = 90/153 (58%), Gaps = 7/153 (4%) Frame = +1 Query: 127 VTFNNGESIPVFGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIK 306 VT N+G IP G GTW+S PG+V AV +A+ GYRH+D A +Y N++EV E I K Sbjct: 7 VTLNSGAQIPQLGFGTWQSAPGQVGDAVYEALKAGYRHLDLATIYQNQREVAEGIKRAYK 66 Query: 307 EGV-VTREDLFITSKLWNTFHRPDLVXGXLQETLDNLNVQYLDLYLIHWPQAYKEDGSLF 483 + + RED+FITSKLWN+ H P +V L E L L + YLDLYL+HWP ++ LF Sbjct: 67 DVPGLKREDIFITSKLWNSQHDPAVVEKALDECLAELELDYLDLYLVHWPVSFTTGSELF 126 Query: 484 PTXQSGKIQ------FSDXDYVDXWKAMEPLXK 564 P + ++ D VD WKAM L K Sbjct: 127 PLVKDSSVEGGDVVINDDISIVDTWKAMTQLPK 159 >UniRef50_Q55FL3 Cluster: Aldo-keto reductase; n=2; Dictyostelium discoideum AX4|Rep: Aldo-keto reductase - Dictyostelium discoideum AX4 Length = 321 Score = 139 bits (337), Expect = 8e-32 Identities = 72/158 (45%), Positives = 97/158 (61%), Gaps = 6/158 (3%) Frame = +1 Query: 136 NNGESIPVFGLGTWKSK-PGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIKEG 312 N+G IP GLGT+ S+ PGEV A+ +A+ GYRHID A YGNEK +G ++ KEG Sbjct: 20 NDGNQIPSIGLGTYYSENPGEVGDAINNALKNGYRHIDGAAFYGNEKVIGNSLKEIFKEG 79 Query: 313 VVTREDLFITSKLWNTFHRPDLVXGXLQETLDNLNVQYLDLYLIHWPQAYKEDGSLFPT- 489 + RED+F TSKLWN+ H +LV +T+++L + YLDLYLIHWP A++ L T Sbjct: 80 EIKREDIFYTSKLWNSCHNSNLVVKHCVKTIEDLGIGYLDLYLIHWPIAFENSNPLGLTI 139 Query: 490 ----XQSGKIQFSDXDYVDXWKAMEPLXKEGLVXSIGV 591 Q+G + + W+ ME L + GLV SIGV Sbjct: 140 EPLRDQNGNPIIAPVSIRETWQEMEKLVELGLVKSIGV 177 Score = 37.5 bits (83), Expect = 0.48 Identities = 17/27 (62%), Positives = 19/27 (70%) Frame = +3 Query: 594 NFNSKQLERLLQXATVKPVVNQVECHP 674 NFN + L LL A +KPVVNQVE HP Sbjct: 179 NFNVQNLVDLLTYAKIKPVVNQVEIHP 205 >UniRef50_Q8SSK6 Cluster: ALDOSE REDUCTASE; n=1; Encephalitozoon cuniculi|Rep: ALDOSE REDUCTASE - Encephalitozoon cuniculi Length = 301 Score = 139 bits (337), Expect = 8e-32 Identities = 71/155 (45%), Positives = 95/155 (61%), Gaps = 3/155 (1%) Frame = +1 Query: 136 NNGESIPVFGLGTWKSKPGEVTQ-AVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIKEG 312 NNG+ IP GLGTW + V + A+++A+ +GYRHID A++YGNEK +G + EG Sbjct: 9 NNGKEIPTVGLGTWGMEDEAVLEGAIRNALSLGYRHIDTAFIYGNEKMIGNILKKLFDEG 68 Query: 313 VVTREDLFITSKLWNTFHRPDLVXGXLQETLDNLNVQYLDLYLIHWPQAY--KEDGSLFP 486 VV R+DLFITSKLWNTFH L+ +L++L + Y+DLYLIHWP + DG++ Sbjct: 69 VVQRKDLFITSKLWNTFH--GCPEDGLRRSLNDLQMDYVDLYLIHWPVTFDPAPDGTVES 126 Query: 487 TXQSGKIQFSDXDYVDXWKAMEPLXKEGLVXSIGV 591 + K D V WK ME L GL SIG+ Sbjct: 127 CGK--KYNVGKFDAVGVWKKMEALVDLGLAKSIGI 159 >UniRef50_A2FPE2 Cluster: Oxidoreductase, aldo/keto reductase family protein; n=3; Trichomonas vaginalis G3|Rep: Oxidoreductase, aldo/keto reductase family protein - Trichomonas vaginalis G3 Length = 309 Score = 137 bits (332), Expect = 3e-31 Identities = 69/153 (45%), Positives = 98/153 (64%), Gaps = 4/153 (2%) Frame = +1 Query: 145 ESIPVFGLGTWKSK-PGEVTQAVKDAI-DIGYRHIDCAYVYGNEKEVGEAITSKIKEGVV 318 E IP GLGT+ ++ P + AV AI D GYRH+DCA Y N++ +GEA++ +G V Sbjct: 2 EVIPSIGLGTFLAEDPAALKAAVHSAIEDSGYRHVDCAAYYKNQEIIGEALSEIFAKGQV 61 Query: 319 TREDLFITSKLWNTFHRPDLVXGXLQETLDNLNVQYLDLYLIHWPQAY--KEDGSLFPTX 492 RE+++ITSK+WNT HRPDL+ +++TL L ++YLDL L+HW A+ +ED P Sbjct: 62 KREEVWITSKVWNTKHRPDLLVKDVKKTLKELKLEYLDLVLVHWACAFQSREDDEYLPRD 121 Query: 493 QSGKIQFSDXDYVDXWKAMEPLXKEGLVXSIGV 591 ++GKI + D ++ WKAME GL IGV Sbjct: 122 ETGKIITENIDILETWKAMEECYNLGLAKHIGV 154 >UniRef50_Q9U2J5 Cluster: Putative uncharacterized protein; n=2; Caenorhabditis|Rep: Putative uncharacterized protein - Caenorhabditis elegans Length = 339 Score = 137 bits (331), Expect = 4e-31 Identities = 64/165 (38%), Positives = 96/165 (58%), Gaps = 5/165 (3%) Frame = +1 Query: 112 PKIPVVTFNNGESIPVFGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAI 291 P VT N+G +PV G GTW+ + V+DA++ GYRHID A + N++EV I Sbjct: 2 PIADTVTLNSGYEMPVIGYGTWQLPKNLAAERVRDALEAGYRHIDSALSFKNQEEVAAGI 61 Query: 292 TSKIKEGVVTREDLFITSKLWNTFHRPDLVXGXLQETLDNLNVQYLDLYLIHWPQAYKED 471 K V RE+LF++SK+WNT+H + + E L+ Y+DL +IHWP + ED Sbjct: 62 KDWCKIRKVRREELFLSSKIWNTYHSRNRCMQQIDEMLEIFETTYMDLIVIHWPFGWAED 121 Query: 472 -----GSLFPTXQSGKIQFSDXDYVDXWKAMEPLXKEGLVXSIGV 591 L+P +GK+++SD DY++ WKA+E + G + SIG+ Sbjct: 122 EPPGERGLWPRGANGKMRYSDVDYLETWKALEDAHRSGKIRSIGL 166 >UniRef50_Q22352 Cluster: Putative uncharacterized protein T08H10.1; n=2; Caenorhabditis|Rep: Putative uncharacterized protein T08H10.1 - Caenorhabditis elegans Length = 333 Score = 136 bits (330), Expect = 6e-31 Identities = 64/157 (40%), Positives = 102/157 (64%), Gaps = 2/157 (1%) Frame = +1 Query: 127 VTFNNGESIPVFGLGTWKSKP-GEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKI 303 + N G +P+FGLGTW+ K E+T A++ A+D GYR ID A++Y NE +G+ + I Sbjct: 6 IPLNTGAQLPLFGLGTWQVKDEAELTVALRAALDAGYRLIDTAHLYQNEHIIGKVLHEYI 65 Query: 304 KEGVVTREDLFITSKLWNTFHRPDLVXGXLQETLDNLNVQYLDLYLIHWPQAYK-EDGSL 480 G + RED+F+TSKL T H P+ V ++ L L ++Y+DLYLIH P +K ++GS Sbjct: 66 SSGKLKREDIFVTSKLPFTAHAPEDVPKCVESQLKALQLEYIDLYLIHCPFPFKHQEGSF 125 Query: 481 FPTXQSGKIQFSDXDYVDXWKAMEPLXKEGLVXSIGV 591 P ++G++ ++ ++D W+A+E L KEG + ++GV Sbjct: 126 APLMENGELAVTEIAHIDTWRALEKLYKEGKLKALGV 162 >UniRef50_P38715 Cluster: NADPH-dependent aldose reductase GRE3; n=39; cellular organisms|Rep: NADPH-dependent aldose reductase GRE3 - Saccharomyces cerevisiae (Baker's yeast) Length = 327 Score = 134 bits (324), Expect = 3e-30 Identities = 71/166 (42%), Positives = 97/166 (58%), Gaps = 10/166 (6%) Frame = +1 Query: 124 VVTFNNGESIPVFGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKI 303 +VT NNG +P+ GLG WK + +AI +GYR D A YGNEKEVGE I I Sbjct: 4 LVTLNNGLKMPLVGLGCWKIDKKVCANQIYEAIKLGYRLFDGACDYGNEKEVGEGIRKAI 63 Query: 304 KEGVVTREDLFITSKLWNTFHRPDLVXGXLQETLDNLNVQYLDLYLIHWPQAYK--EDGS 477 EG+V+R+D+F+ SKLWN FH PD V L++TL ++ + YLDLY IH+P A+K Sbjct: 64 SEGLVSRKDIFVVSKLWNNFHHPDHVKLALKKTLSDMGLDYLDLYYIHFPIAFKYVPFEE 123 Query: 478 LFPTX--------QSGKIQFSDXDYVDXWKAMEPLXKEGLVXSIGV 591 +P + G I + +D ++A+E EGL+ SIGV Sbjct: 124 KYPPGFYTGADDEKKGHITEAHVPIIDTYRALEECVDEGLIKSIGV 169 >UniRef50_UPI0000E45E29 Cluster: PREDICTED: similar to aldose reductase; n=1; Strongylocentrotus purpuratus|Rep: PREDICTED: similar to aldose reductase - Strongylocentrotus purpuratus Length = 274 Score = 134 bits (323), Expect = 4e-30 Identities = 60/97 (61%), Positives = 68/97 (70%) Frame = +1 Query: 175 WKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIKEGVVTREDLFITSKLW 354 W SKPG+V AVK AID GYRHIDCA+VYGNE EVG + K VV RED+FITSKLW Sbjct: 5 WMSKPGQVEAAVKAAIDCGYRHIDCAHVYGNEAEVGAGLKEKFDANVVKREDIFITSKLW 64 Query: 355 NTFHRPDLVXGXLQETLDNLNVQYLDLYLIHWPQAYK 465 N H PD V TL NL + Y+DLYL+HWP AY+ Sbjct: 65 NNKHHPDDVEQACDITLKNLQLSYVDLYLMHWPMAYQ 101 Score = 35.9 bits (79), Expect = 1.5 Identities = 15/34 (44%), Positives = 24/34 (70%) Frame = +3 Query: 594 NFNSKQLERLLQXATVKPVVNQVECHPLPHQKXL 695 NF+ K ++R+++ AT++P QVE HPL Q+ L Sbjct: 119 NFSMKMMKRVIEKATIQPANLQVELHPLLTQEKL 152 >UniRef50_Q7ZA52 Cluster: Aldose reductase; n=6; Pezizomycotina|Rep: Aldose reductase - Magnaporthe grisea (Rice blast fungus) (Pyricularia grisea) Length = 312 Score = 134 bits (323), Expect = 4e-30 Identities = 71/158 (44%), Positives = 91/158 (57%), Gaps = 4/158 (2%) Frame = +1 Query: 130 TFNNGESIPVFGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIKE 309 T N G IP FGLGTW+ G + +AV AI GYR ID AYVYGNE+EVG+ I I Sbjct: 7 TLNTGAKIPAFGLGTWQGDKGVIKEAVLTAIKSGYRLIDGAYVYGNEEEVGQGIREAISS 66 Query: 310 GVVTREDLFITSKLWNTF-HRPDLVXGXLQETLDNLNVQYLDLYLIHWPQAYKEDGS--L 480 G+V REDLF+ SK W T+ R +L L ++L L + Y+DLYL+HWP +G+ Sbjct: 67 GIVKREDLFVVSKCWATYTTRCEL---GLDQSLKLLGLDYVDLYLVHWPILMNPEGNDEK 123 Query: 481 FPTXQSGKIQ-FSDXDYVDXWKAMEPLXKEGLVXSIGV 591 FP G ++VD WK ME L G ++GV Sbjct: 124 FPKHADGSRDIIHTHNHVDTWKLMEKLPATGKTKAVGV 161 Score = 35.9 bits (79), Expect = 1.5 Identities = 18/33 (54%), Positives = 22/33 (66%), Gaps = 1/33 (3%) Frame = +3 Query: 594 NFNSKQLERLLQXATVKPVVNQVECHP-LPHQK 689 N++ LE+LL AT P VNQVE HP LP Q+ Sbjct: 163 NYSKAWLEQLLPHATTVPAVNQVENHPQLPQQE 195 >UniRef50_Q2UGR1 Cluster: Aldo/keto reductase family proteins; n=2; Ascomycota|Rep: Aldo/keto reductase family proteins - Aspergillus oryzae Length = 323 Score = 133 bits (322), Expect = 5e-30 Identities = 69/154 (44%), Positives = 93/154 (60%), Gaps = 2/154 (1%) Frame = +1 Query: 136 NNGESIPVFGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIKEGV 315 N+G +IP GLGTW SKP EV AV+ A+ GYRHID A Y NE EVG K+ Sbjct: 10 NSGYNIPAIGLGTWLSKPHEVENAVEAALRAGYRHIDAAACYQNENEVGNGW----KKSG 65 Query: 316 VTREDLFITSKLWNTFHRPDLVXGXLQETLDNLNVQYLDLYLIHWPQAYKE-DGSLFPTX 492 V R+ +FITSKLWNT H P+ V + +TL +L YLDLYLIHWP A++ + +L P Sbjct: 66 VPRDQIFITSKLWNTHHHPEHVEEAVNKTLKDLQTDYLDLYLIHWPVAFEHTNETLTPID 125 Query: 493 Q-SGKIQFSDXDYVDXWKAMEPLXKEGLVXSIGV 591 + + + ++ D W A+E L + + SIG+ Sbjct: 126 PVTKRFRLANVPIADTWAALEKLVEAKKIRSIGI 159 Score = 34.3 bits (75), Expect = 4.4 Identities = 14/34 (41%), Positives = 20/34 (58%) Frame = +3 Query: 594 NFNSKQLERLLQXATVKPVVNQVECHPLPHQKXL 695 NF +++ LL+ A + P VNQ+E HP Q L Sbjct: 161 NFTQDKIDDLLKTAKIPPAVNQIEAHPYLQQPGL 194 >UniRef50_Q1YPE5 Cluster: Aldehyde reductase; n=7; Bacteria|Rep: Aldehyde reductase - gamma proteobacterium HTCC2207 Length = 330 Score = 133 bits (321), Expect = 7e-30 Identities = 71/170 (41%), Positives = 103/170 (60%), Gaps = 9/170 (5%) Frame = +1 Query: 109 APKIPVVTFNNGESIPVFGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEA 288 A ++P V ++ +S+P GLG WK QAV +AI +GYRH+D A YGNE++VGE Sbjct: 4 AIQVPGVKVSS-KSMPAVGLGLWKITQDSAAQAVYEAIKVGYRHLDSAADYGNEQQVGEG 62 Query: 289 ITSKIKEGVVTREDLFITSKLWNTFHRPDLVXGXLQETLDNLNVQYLDLYLIHWPQA--Y 462 I I EG+ +RE+L+IT+KLWNT+HR + V + ++D+L + Y+DLYL+H+P A Y Sbjct: 63 IARAIAEGLCSREELWITTKLWNTYHRAEHVEAACRRSMDDLGLDYIDLYLVHFPIALRY 122 Query: 463 KEDGSLFPT----XQSGKIQFSDXDYV---DXWKAMEPLXKEGLVXSIGV 591 + +P S + + D V + W AME L + GLV IGV Sbjct: 123 VDFNDRYPAEWIFDHSAEDPAMELDQVPLSETWGAMEQLVESGLVRQIGV 172 >UniRef50_Q4PAT5 Cluster: Putative uncharacterized protein; n=1; Ustilago maydis|Rep: Putative uncharacterized protein - Ustilago maydis (Smut fungus) Length = 700 Score = 132 bits (319), Expect = 1e-29 Identities = 69/160 (43%), Positives = 95/160 (59%), Gaps = 6/160 (3%) Frame = +1 Query: 130 TFNNGESIPVFGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIKE 309 T NG IP G GTWK + T AV AI GYRHIDCA+ Y NE +A+ + IK+ Sbjct: 13 TLANGAQIPKLGFGTWKMSKEQATPAVAHAIKTGYRHIDCAWAYRNE----DAVAAGIKK 68 Query: 310 GVVTREDLFITSKLWNTFHRPDLVXGXLQETLDNLNVQYLDLYLIHWPQAY-KEDGSLFP 486 V R L++TSKLWN+FH P+ V L +L +L YLDLYL+HWP A+ GS+ P Sbjct: 69 AGVPRSQLWLTSKLWNSFHHPEHVEKALDASLKDLGTDYLDLYLMHWPVAFLNSKGSMVP 128 Query: 487 TXQS---GKIQFSD--XDYVDXWKAMEPLXKEGLVXSIGV 591 + +S ++ D D++ ++ ME + K+G V +IGV Sbjct: 129 SIRSTGGHPVESEDLSRDFMATYRVMEEMVKKGKVRNIGV 168 >UniRef50_Q1U9L6 Cluster: 2,5-didehydrogluconate reductase; n=3; Lactobacillus|Rep: 2,5-didehydrogluconate reductase - Lactobacillus reuteri 100-23 Length = 288 Score = 131 bits (317), Expect = 2e-29 Identities = 72/152 (47%), Positives = 90/152 (59%) Frame = +1 Query: 136 NNGESIPVFGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIKEGV 315 NNG IP G GT+++ QAVK+AI+ GYRHID A VYGNE+ VG+ I K+ Sbjct: 14 NNGVKIPCVGYGTFRTPADVAEQAVKEAIETGYRHIDTAAVYGNEEAVGKGI----KDSG 69 Query: 316 VTREDLFITSKLWNTFHRPDLVXGXLQETLDNLNVQYLDLYLIHWPQAYKEDGSLFPTXQ 495 + REDLF+TSKLWNT + QETLD L + YLDLYLIHWP K+ G Sbjct: 70 IKREDLFVTSKLWNTNRGYEQTKKAFQETLDRLQMDYLDLYLIHWPANEKQFGD-----D 124 Query: 496 SGKIQFSDXDYVDXWKAMEPLXKEGLVXSIGV 591 + KI + W+AME L EG + +IGV Sbjct: 125 AAKIN------AETWRAMEDLYNEGKIRAIGV 150 >UniRef50_Q5KI95 Cluster: Aldo-keto reductase, putative; n=14; Dikarya|Rep: Aldo-keto reductase, putative - Cryptococcus neoformans (Filobasidiella neoformans) Length = 353 Score = 131 bits (317), Expect = 2e-29 Identities = 71/155 (45%), Positives = 89/155 (57%), Gaps = 3/155 (1%) Frame = +1 Query: 136 NNGESIPVFGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIKEGV 315 N G SIP GLGTW++K GEV QAV A+ GYRHID A Y NE EVG IK+ Sbjct: 42 NTGASIPAIGLGTWQAKAGEVRQAVAHALKAGYRHIDGALCYQNEDEVGLG----IKDSG 97 Query: 316 VTREDLFITSKLWNTFHRPDLVXGXLQETLDNLNVQYLDLYLIHWPQAYKEDGS--LFPT 489 V R ++F+TSK+W+++H D V L TL +L YLDLYLIHWP +G+ LFP Sbjct: 98 VPRSEIFLTSKVWSSYH--DRVEECLDTTLKSLQTDYLDLYLIHWPVRLAPNGTHPLFPV 155 Query: 490 XQSGKIQFS-DXDYVDXWKAMEPLXKEGLVXSIGV 591 G D D W ME + K+G +IG+ Sbjct: 156 KPDGSRNLDWDWDQAKTWAQMEDVLKKGKAKAIGL 190 >UniRef50_A2EYY6 Cluster: Oxidoreductase, aldo/keto reductase family protein; n=9; Trichomonas vaginalis G3|Rep: Oxidoreductase, aldo/keto reductase family protein - Trichomonas vaginalis G3 Length = 308 Score = 130 bits (315), Expect = 4e-29 Identities = 73/156 (46%), Positives = 96/156 (61%), Gaps = 9/156 (5%) Frame = +1 Query: 151 IPVFGLGTWKSKPGE-----VTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIKEGV 315 IP GLGTWKS E +T A+K+A GY HIDCA Y NE VG+A+ G+ Sbjct: 4 IPTIGLGTWKSPRSEDLVNAITYAIKEA---GYVHIDCALCYENEDIVGQALQQCWDSGI 60 Query: 316 VTREDLFITSKLWNTFHRPDLVXGXLQETLDNLNVQYLDLYLIHWPQAYKE---DGSLFP 486 RE+++ITSKLWNT HR ++V ++TL +L + YLDLYL+H+P A++ GSL P Sbjct: 61 -KRENIWITSKLWNTHHRLEIVEEACRKTLKDLRLDYLDLYLMHYPFAFQNTGIGGSLNP 119 Query: 487 TXQSGKIQFSD-XDYVDXWKAMEPLXKEGLVXSIGV 591 + G F D +D WKAME L ++GLV IGV Sbjct: 120 LDEKGNTIFDDGVSLIDTWKAMEKLVEKGLVKRIGV 155 >UniRef50_Q9Y020 Cluster: 3-dehydroecdysone 3beta-reductase precursor; n=1; Spodoptera littoralis|Rep: 3-dehydroecdysone 3beta-reductase precursor - Spodoptera littoralis (Egyptian cotton leafworm) Length = 345 Score = 130 bits (314), Expect = 5e-29 Identities = 68/167 (40%), Positives = 96/167 (57%), Gaps = 9/167 (5%) Frame = +1 Query: 118 IPVVTFNNGESIPVFGLGTW---------KSKPGEVTQAVKDAIDIGYRHIDCAYVYGNE 270 +P++ N +P LGT+ SK ++ V AID+GYRH D A +Y E Sbjct: 22 VPMLKMLNDREMPAIALGTYLGFDKGGAVTSKDKQLRNVVMQAIDLGYRHFDTAAIYNTE 81 Query: 271 KEVGEAITSKIKEGVVTREDLFITSKLWNTFHRPDLVXGXLQETLDNLNVQYLDLYLIHW 450 EVGEAI KI EGV+ RED+F+T+KLWNT H+ + V ++ETL+ + Y+DL+L+HW Sbjct: 82 AEVGEAIRMKIDEGVIKREDVFLTTKLWNTHHKREQVAVAMKETLNKTGLDYVDLFLMHW 141 Query: 451 PQAYKEDGSLFPTXQSGKIQFSDXDYVDXWKAMEPLXKEGLVXSIGV 591 P A ED S S+ DY++ W+A E + K G SIG+ Sbjct: 142 PIALNEDYS-----------HSNTDYLETWRATEEMVKLGYTKSIGL 177 Score = 35.9 bits (79), Expect = 1.5 Identities = 17/42 (40%), Positives = 24/42 (57%) Frame = +3 Query: 594 NFNSKQLERLLQXATVKPVVNQVECHPLPHQKXLXSSVRLAG 719 NFN Q+ +LQ T+KPV Q+E HP Q+ L + + G Sbjct: 179 NFNKLQVATVLQECTIKPVALQIEVHPQIIQEDLITYAKDEG 220 >UniRef50_Q9VHX4 Cluster: CG2767-PA; n=4; Endopterygota|Rep: CG2767-PA - Drosophila melanogaster (Fruit fly) Length = 329 Score = 130 bits (314), Expect = 5e-29 Identities = 66/158 (41%), Positives = 98/158 (62%), Gaps = 3/158 (1%) Frame = +1 Query: 127 VTFNNGESIPVFGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIK 306 +TFNNGE +PV G+GTW++ E+ A+ A++ GYRHID A VYGNEK +G + + Sbjct: 7 LTFNNGEKMPVIGIGTWQASDEEIETAIDAALEAGYRHIDTAPVYGNEKAIGRVLKRWLD 66 Query: 307 EGVVTREDLFITSKLWNTFHRPDLVXGXLQETLDNLNVQYLDLYLIHWPQA--YKEDGSL 480 G V RE+LFI +K+ +RP V ++++L++L + Y+DLYL+H P EDGS Sbjct: 67 AGKVKREELFIVTKVPPVSNRPHEVEPTIKKSLEDLQLDYVDLYLVHTPFTININEDGS- 125 Query: 481 FPTXQSGKIQFS-DXDYVDXWKAMEPLXKEGLVXSIGV 591 F + G ++ ++ W AME L ++GL SIGV Sbjct: 126 FKLDKEGLMEVDVTTNHAAIWVAMEALVEKGLTKSIGV 163 >UniRef50_Q7ZWA4 Cluster: Zgc:56622; n=6; cellular organisms|Rep: Zgc:56622 - Danio rerio (Zebrafish) (Brachydanio rerio) Length = 289 Score = 129 bits (312), Expect = 9e-29 Identities = 63/131 (48%), Positives = 86/131 (65%), Gaps = 1/131 (0%) Frame = +1 Query: 202 QAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIKEGVVTREDLFITSKLWNTFHRPDLV 381 +A + AI GYRHID A+ Y NE +VG AI +KI++G++ R+D+FI SKLW T H P+ + Sbjct: 4 RACEAAIAAGYRHIDTAFCYRNEVDVGMAIQNKIQQGIIRRQDMFIVSKLWGTHHAPEDI 63 Query: 382 XGXLQETLDNLNVQYLDLYLIHWPQAYKEDG-SLFPTXQSGKIQFSDXDYVDXWKAMEPL 558 ++L +L + YLD YL+H+P K+ G LFP + GKI +D DYVD W+ ME L Sbjct: 64 PVCFNKSLSDLQLDYLDQYLVHFPVGLKKVGDELFP-ERDGKILTTDIDYVDVWRGMEAL 122 Query: 559 XKEGLVXSIGV 591 G V SIGV Sbjct: 123 KATGKVKSIGV 133 Score = 37.9 bits (84), Expect = 0.36 Identities = 17/34 (50%), Positives = 21/34 (61%) Frame = +3 Query: 594 NFNSKQLERLLQXATVKPVVNQVECHPLPHQKXL 695 NF +Q++RLL A + P VNQVE HP Q L Sbjct: 135 NFTMEQIDRLLSVAKIPPAVNQVELHPYLVQSDL 168 >UniRef50_Q5T2L2 Cluster: Aldo-keto reductase family 1 member C-like protein 1; n=14; Eutheria|Rep: Aldo-keto reductase family 1 member C-like protein 1 - Homo sapiens (Human) Length = 302 Score = 129 bits (311), Expect = 1e-28 Identities = 67/153 (43%), Positives = 91/153 (59%), Gaps = 4/153 (2%) Frame = +1 Query: 127 VTFNNGESIPVFGLGTWK---SKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITS 297 V N+G +PV G GT+ + + +A K AID+G+RHID AY+Y NE+EVG+AI Sbjct: 11 VRLNDGPFMPVLGFGTYAPDHTPKSQAAEATKVAIDVGFRHIDSAYLYQNEEEVGQAIWE 70 Query: 298 KIKEGVVTREDLFITSKLWNTFHRPDLVXGXLQETLDNLNVQYLDLYLIHWPQAYKEDG- 474 KI +G V RE++F T KLW TF R +LV L+ +L L Y+DL++IH P A K+ G Sbjct: 71 KIADGTVKREEIFYTIKLWATFFRAELVHPALERSLKKLGPDYVDLFIIHVPFAMKQPGK 130 Query: 475 SLFPTXQSGKIQFSDXDYVDXWKAMEPLXKEGL 573 L P SG+I + D W+ L K GL Sbjct: 131 ELLPKDASGEIILETVELCDTWELELILNKPGL 163 >UniRef50_UPI0000499B0E Cluster: oxidoreductase, aldo/keto reductase family; n=1; Entamoeba histolytica HM-1:IMSS|Rep: oxidoreductase, aldo/keto reductase family - Entamoeba histolytica HM-1:IMSS Length = 307 Score = 128 bits (310), Expect = 1e-28 Identities = 72/153 (47%), Positives = 92/153 (60%), Gaps = 1/153 (0%) Frame = +1 Query: 136 NNGESIPVFGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGE-AITSKIKEG 312 NNG+ +P GLGTW + PGEV +AV A++ GYR IDCA Y NEKE+GE I +K Sbjct: 9 NNGKFMPAIGLGTWLAAPGEVGKAVTLALENGYRLIDCARFYKNEKEIGEMGIEPFLKNH 68 Query: 313 VVTREDLFITSKLWNTFHRPDLVXGXLQETLDNLNVQYLDLYLIHWPQAYKEDGSLFPTX 492 RE+LF+TSKLW + + E++ +L +YLDLYLIHWP A K D S P Sbjct: 69 --PREELFVTSKLW--MDQVTRIRESCLESIQDLKCKYLDLYLIHWPIALKVDASNPPKP 124 Query: 493 QSGKIQFSDXDYVDXWKAMEPLXKEGLVXSIGV 591 + F D D + W+ ME L EGLV SIG+ Sbjct: 125 E----DFLDMDITEIWQEMERLVDEGLVKSIGL 153 >UniRef50_Q4FY75 Cluster: Aldo-keto reductase-like protein; n=5; Trypanosomatidae|Rep: Aldo-keto reductase-like protein - Leishmania major strain Friedlin Length = 372 Score = 127 bits (307), Expect = 3e-28 Identities = 66/162 (40%), Positives = 85/162 (52%), Gaps = 7/162 (4%) Frame = +1 Query: 127 VTFNNGESIPVFGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIK 306 + + +IP G GT++ E T AV A+ GYRH+DCA YGNE VGEA+ ++ Sbjct: 22 IAMRDSHTIPQLGFGTYRLPVSEATDAVAFALSCGYRHVDCAKAYGNEAAVGEALAQALR 81 Query: 307 EGVVTREDLFITSKLWNTFHRPDLVXGXLQETLDNLNVQYLDLYLIHWPQA------YKE 468 REDLF+TSKLW T PD V + TL L + YLDLYLIHWP + Sbjct: 82 TRCTRREDLFVTSKLWPTDQHPDHVEAACRATLAALQLDYLDLYLIHWPVCMRHTPHWTS 141 Query: 469 DGSLFPTXQSGKIQF-SDXDYVDXWKAMEPLXKEGLVXSIGV 591 D +P + G + +D W AM L GLV SIG+ Sbjct: 142 DEDRYPRHRDGTPAIDTSVTLLDTWTAMNRLVDRGLVKSIGL 183 >UniRef50_Q41399 Cluster: Chalcone reductase; n=4; eudicotyledons|Rep: Chalcone reductase - Sesbania rostrata Length = 322 Score = 126 bits (305), Expect = 6e-28 Identities = 68/163 (41%), Positives = 95/163 (58%), Gaps = 4/163 (2%) Frame = +1 Query: 115 KIPVVTFNNGESIPVFGLGTW-KSKPGE--VTQAVKDAIDIGYRHIDCAYVYGNEKEVGE 285 KIP V N+G +PV G+GT +S+P + DAI +GYRH D A VYG E+ +G Sbjct: 5 KIPEVLLNSGHKMPVIGMGTSVESRPSNDVLASIFVDAIQVGYRHFDSASVYGTEEAIGM 64 Query: 286 AITSKIKEGVV-TREDLFITSKLWNTFHRPDLVXGXLQETLDNLNVQYLDLYLIHWPQAY 462 A++ I++G++ +R+++FITSK WNT DL+ L+ TL L ++Y+DLYLIHWP Sbjct: 65 AVSKAIEQGLIKSRDEVFITSKPWNTDAHHDLIVPALKTTLKKLGMEYVDLYLIHWPVRL 124 Query: 463 KEDGSLFPTXQSGKIQFSDXDYVDXWKAMEPLXKEGLVXSIGV 591 + D L K D WKAME + GL SIG+ Sbjct: 125 RHD--LENPVIFSKEDLLPFDIEGTWKAMEECYRLGLAKSIGI 165 Score = 36.3 bits (80), Expect = 1.1 Identities = 17/42 (40%), Positives = 25/42 (59%) Frame = +3 Query: 594 NFNSKQLERLLQXATVKPVVNQVECHPLPHQKXLXSSVRLAG 719 N+ +K+L +LL+ AT+ P VNQVE +P Q L + G Sbjct: 167 NYGTKKLTKLLEIATIPPAVNQVEMNPSWQQGNLREFCKQKG 208 >UniRef50_Q8WRT0 Cluster: 3-dehydrecdysone 3b-reductase; n=1; Trichoplusia ni|Rep: 3-dehydrecdysone 3b-reductase - Trichoplusia ni (Cabbage looper) Length = 308 Score = 126 bits (305), Expect = 6e-28 Identities = 72/160 (45%), Positives = 94/160 (58%), Gaps = 1/160 (0%) Frame = +1 Query: 115 KIPVVTFNNGESIPVFGLGTWK-SKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAI 291 K P+ N+G +IP LGT+ +V QAV AI GYRHID A +YGNE+EVG+ I Sbjct: 23 KAPLKQLNDGNAIPSLALGTFGFGDIPKVRQAVLWAIQAGYRHIDTAALYGNEEEVGKGI 82 Query: 292 TSKIKEGVVTREDLFITSKLWNTFHRPDLVXGXLQETLDNLNVQYLDLYLIHWPQAYKED 471 I++G+V RE+LF+T+KLWN H V L+E+L L + Y+DLYLIH P+A E+ Sbjct: 83 ADAIQQGLVKREELFVTTKLWNDKHGRHQVVPALRESLTKLGLSYVDLYLIHSPEATNEN 142 Query: 472 GSLFPTXQSGKIQFSDXDYVDXWKAMEPLXKEGLVXSIGV 591 G P D D ++ W ME K GL SIGV Sbjct: 143 GD--PV---------DIDVLNTWNGMEEAKKLGLAKSIGV 171 Score = 33.5 bits (73), Expect = 7.8 Identities = 14/34 (41%), Positives = 21/34 (61%) Frame = +3 Query: 594 NFNSKQLERLLQXATVKPVVNQVECHPLPHQKXL 695 NF++ L+RL+ + P VNQ+E HP Q+ L Sbjct: 173 NFDTALLDRLIAGSNTVPAVNQIEVHPSKTQEKL 206 >UniRef50_Q7PLK6 Cluster: CG40064-PA; n=1; Drosophila melanogaster|Rep: CG40064-PA - Drosophila melanogaster (Fruit fly) Length = 361 Score = 126 bits (305), Expect = 6e-28 Identities = 62/135 (45%), Positives = 89/135 (65%), Gaps = 2/135 (1%) Frame = +1 Query: 193 EVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIKEGVVTREDLFITSKLWNTFHRP 372 + + AV AI+ G+RH D AY Y NEKE+GEA+ ++IK G ++RE++F+T+KLWNT H P Sbjct: 45 QCSAAVHCAIETGFRHFDTAYYYENEKEIGEALRTQIKMGNISRENIFLTTKLWNTHHDP 104 Query: 373 DLVXGXLQETLDNLNVQYLDLYLIHWPQAYKE--DGSLFPTXQSGKIQFSDXDYVDXWKA 546 V ++ L+ L Y+DLYL+H+P YK D L P ++Q + DY+D W+A Sbjct: 105 RDVRRICEKQLELLGFSYIDLYLMHFPVGYKYVCDEILMP-MSGDELQTVEIDYLDTWRA 163 Query: 547 MEPLXKEGLVXSIGV 591 ME L K G+V SIG+ Sbjct: 164 MENLVKLGMVRSIGL 178 Score = 40.3 bits (90), Expect = 0.068 Identities = 20/42 (47%), Positives = 27/42 (64%) Frame = +3 Query: 594 NFNSKQLERLLQXATVKPVVNQVECHPLPHQKXLXSSVRLAG 719 NFN +Q++R++Q ++ KPVVNQVE P QK L R G Sbjct: 180 NFNMEQIQRIIQCSSSKPVVNQVEIWPGFLQKDLVDYCRYNG 221 >UniRef50_Q6TY50 Cluster: Reductase 2; n=10; Magnoliophyta|Rep: Reductase 2 - Hydrangea macrophylla (Bigleaf hydrangea) Length = 321 Score = 126 bits (303), Expect = 1e-27 Identities = 70/167 (41%), Positives = 100/167 (59%), Gaps = 5/167 (2%) Frame = +1 Query: 106 MAPKIPVVTFNNG-ESIPVFGLGTWKSKPGE---VTQAVKDAIDIGYRHIDCAYVYGNEK 273 MA IP V ++G +PV GLGT P + V +AV +A+ +GYRH D A +Y +E+ Sbjct: 1 MAFTIPEVPLSSGGRKMPVLGLGTAADPPVDPETVRKAVTEALKLGYRHFDTAALYNSEQ 60 Query: 274 EVGEAITSKIKEGVV-TREDLFITSKLWNTFHRPDLVXGXLQETLDNLNVQYLDLYLIHW 450 +G+AI + EG++ +R++LFITSKLW + + V LQ+TL NL ++Y+D+YLIHW Sbjct: 61 PLGDAIAEALGEGLIKSRDELFITSKLWCSDAHRENVEPALQKTLKNLKLEYIDMYLIHW 120 Query: 451 PQAYKEDGSLFPTXQSGKIQFSDXDYVDXWKAMEPLXKEGLVXSIGV 591 P + K +P K F DY W+AME K GL +IGV Sbjct: 121 PVSSKPGNYEYPIK---KEDFLQMDYKSVWEAMEECQKLGLTKAIGV 164 Score = 34.3 bits (75), Expect = 4.4 Identities = 17/34 (50%), Positives = 21/34 (61%) Frame = +3 Query: 594 NFNSKQLERLLQXATVKPVVNQVECHPLPHQKXL 695 NF+ K+L +L A V P VNQVE +P QK L Sbjct: 166 NFSCKKLSDVLANAKVPPAVNQVEVNPCWQQKQL 199 >UniRef50_A2EHN6 Cluster: Oxidoreductase, aldo/keto reductase family protein; n=10; Trichomonas vaginalis|Rep: Oxidoreductase, aldo/keto reductase family protein - Trichomonas vaginalis G3 Length = 312 Score = 126 bits (303), Expect = 1e-27 Identities = 65/153 (42%), Positives = 92/153 (60%), Gaps = 6/153 (3%) Frame = +1 Query: 151 IPVFGLGTWKSK-PGEVTQAVKDAID-IGYRHIDCAYVYGNEKEVGEAITSKIKEGVVTR 324 IP G GT+ + P ++ A+ AI+ G RHID A+ Y N+ +GE + +G + R Sbjct: 3 IPQLGFGTYLANDPAKLKAALHYAIEECGVRHIDTAFAYYNQNVIGETLKEIFAKGKIKR 62 Query: 325 EDLFITSKLWNTFHRPDLVXGXLQETLDNLNVQYLDLYLIHWPQAYK----EDGSLFPTX 492 ED+FIT+KLW T HR DLV L E L L + Y+DL+LIH P A+K +DG++ P Sbjct: 63 EDMFITTKLWCTHHRKDLVEPELHENLAQLQLSYVDLFLIHQPIAFKSLPAKDGTMMPKD 122 Query: 493 QSGKIQFSDXDYVDXWKAMEPLXKEGLVXSIGV 591 + GKIQ+ D ++ + AME K+GL IGV Sbjct: 123 EKGKIQYEQIDILETYHAMEECQKKGLTRHIGV 155 >UniRef50_Q1IN88 Cluster: Aldehyde reductase; n=5; Bacteria|Rep: Aldehyde reductase - Acidobacteria bacterium (strain Ellin345) Length = 313 Score = 125 bits (302), Expect = 1e-27 Identities = 60/148 (40%), Positives = 87/148 (58%), Gaps = 1/148 (0%) Frame = +1 Query: 151 IPVFGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIKEGVVTRED 330 IP G GT + P A +DA+ G+RH DCA Y NE+EVGEA+ + G + RE+ Sbjct: 20 IPALGFGTLIADPALTITATRDALAAGFRHFDCAERYRNEREVGEALRAGRAAGNIAREE 79 Query: 331 LFITSKLWNTFHRPDLVXGXLQETLDNLNVQYLDLYLIHWPQAYKEDGSLFPTXQSGKIQ 510 +F+T+KLWNT HRP+ V + +LD L + YLDLYLIH P A++ P Q+G + Sbjct: 80 IFVTTKLWNTNHRPERVEPAFEASLDRLGLDYLDLYLIHTPFAFQPGDEQDPRDQNGSVI 139 Query: 511 FSDXDYV-DXWKAMEPLXKEGLVXSIGV 591 + + + + W A+E L G +IG+ Sbjct: 140 YDEGVTLRETWSALENLVDRGRCRAIGL 167 >UniRef50_UPI000023D0F1 Cluster: hypothetical protein FG03517.1; n=1; Gibberella zeae PH-1|Rep: hypothetical protein FG03517.1 - Gibberella zeae PH-1 Length = 364 Score = 124 bits (300), Expect = 2e-27 Identities = 67/155 (43%), Positives = 96/155 (61%), Gaps = 3/155 (1%) Frame = +1 Query: 133 FNNGES---IPVFGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKI 303 FN E+ IP FGLGTW + G V AV+ A+ GYRHID A ++ NE EVG+ I Sbjct: 51 FNKNETVRDIPAFGLGTWLAGKGVVVPAVEYALKGGYRHIDTALIWRNEDEVGKGI---- 106 Query: 304 KEGVVTREDLFITSKLWNTFHRPDLVXGXLQETLDNLNVQYLDLYLIHWPQAYKEDGSLF 483 K V+R+++++T KLWNT HRP+LV ++ ++ NL V+YLDLYLIH+P A+ Sbjct: 107 KASGVSRDEIWVTGKLWNTDHRPELVRKAIETSIANLGVEYLDLYLIHYPVAW------- 159 Query: 484 PTXQSGKIQFSDXDYVDXWKAMEPLXKEGLVXSIG 588 ++ + ++ +D WKAME L + GL +IG Sbjct: 160 -VPETRDVD-NNTSLIDTWKAMEELVRAGLTRNIG 192 >UniRef50_Q16K66 Cluster: Aldo-keto reductase; n=2; Aedes aegypti|Rep: Aldo-keto reductase - Aedes aegypti (Yellowfever mosquito) Length = 303 Score = 124 bits (300), Expect = 2e-27 Identities = 65/157 (41%), Positives = 95/157 (60%), Gaps = 1/157 (0%) Frame = +1 Query: 124 VVTFNNGESIPVFGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKI 303 ++ NNG SIP GLGT+K + A+K A++ GYR ID A+VY NE+ VG+A+ Sbjct: 1 MLALNNGHSIPPIGLGTYKITGSDGVAAIKSAVEFGYRLIDTAFVYNNEQVVGQALREIF 60 Query: 304 KEG-VVTREDLFITSKLWNTFHRPDLVXGXLQETLDNLNVQYLDLYLIHWPQAYKEDGSL 480 +G + RED+FI SKL TFHRP+ V + +L+ L + Y+DLYL+H P A ++ G Sbjct: 61 SQGNDINREDVFIVSKLGPTFHRPEAVEKGCRLSLERLGLDYVDLYLMHTPVAARDSGD- 119 Query: 481 FPTXQSGKIQFSDXDYVDXWKAMEPLXKEGLVXSIGV 591 +I + ++ WKA+E ++GLV SIGV Sbjct: 120 --GNDRSEID-DEVTPLETWKALEECQRKGLVRSIGV 153 Score = 35.9 bits (79), Expect = 1.5 Identities = 16/34 (47%), Positives = 22/34 (64%) Frame = +3 Query: 594 NFNSKQLERLLQXATVKPVVNQVECHPLPHQKXL 695 NFN +QL ++ +++PVVNQVEC HQ L Sbjct: 155 NFNEEQLMEIVTHGSIRPVVNQVECSIGFHQVKL 188 >UniRef50_A7PNI3 Cluster: Chromosome chr1 scaffold_22, whole genome shotgun sequence; n=2; Vitis vinifera|Rep: Chromosome chr1 scaffold_22, whole genome shotgun sequence - Vitis vinifera (Grape) Length = 360 Score = 124 bits (299), Expect = 3e-27 Identities = 69/154 (44%), Positives = 90/154 (58%), Gaps = 2/154 (1%) Frame = +1 Query: 136 NNGESIPVFGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIKEGV 315 N IP GLGTW+S +AVK A+ GYR IDCA++YGNE EVGEA+ G Sbjct: 15 NTKAKIPAIGLGTWQSGGDLCVEAVKRALSEGYRQIDCAHLYGNEVEVGEALAEAF-NGS 73 Query: 316 VTREDLFITSKLWNTFHRPDLVXGXLQETLDNLNVQYLDLYLIHWPQAYKEDGSLFPTXQ 495 + RED+F+TSKL+ T + + + ++ +L NL V YLDLYL+HWP + P Sbjct: 74 LKREDVFLTSKLYCTMNSLNKIENSVRVSLKNLGVTYLDLYLMHWPDITAFGDATDPPSN 133 Query: 496 SGK--IQFSDXDYVDXWKAMEPLXKEGLVXSIGV 591 SG QF + WKAME L + GLV +IGV Sbjct: 134 SGNDHRQFLNR-LKKAWKAMEGLIELGLVRAIGV 166 Score = 34.3 bits (75), Expect = 4.4 Identities = 15/34 (44%), Positives = 21/34 (61%) Frame = +3 Query: 594 NFNSKQLERLLQXATVKPVVNQVECHPLPHQKXL 695 NF +Q++ LL+ A + P VNQV+ HP Q L Sbjct: 168 NFGVQQIKELLKFAKIVPAVNQVKLHPFWRQDEL 201 >UniRef50_Q6RZX1 Cluster: Gld1; n=22; Pezizomycotina|Rep: Gld1 - Trichoderma atroviride (Hypocrea atroviridis) Length = 327 Score = 122 bits (295), Expect = 1e-26 Identities = 66/161 (40%), Positives = 91/161 (56%), Gaps = 7/161 (4%) Frame = +1 Query: 130 TFNNGESIPVFGLGTWKSK--PGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKI 303 T N G IP G GT+ ++ GE AV A+D+GYRH+DCA+ Y NE EVG+AI + Sbjct: 16 TLNTGAKIPAVGFGTFANEGAKGETYAAVTKALDVGYRHLDCAWFYLNEDEVGDAIRDFL 75 Query: 304 -KEGVVTREDLFITSKLWNTFHRPDLVXGXLQETLDNLNVQYLDLYLIHWP-QAYKEDGS 477 + VTR+DLFI +K+WN H P+ V + + +NL V Y+DL+L+HWP A K Sbjct: 76 ARRPDVTRKDLFICTKVWNHLHEPEDVKWSAKNSCENLKVDYIDLFLVHWPIAAEKNADR 135 Query: 478 LFPTXQSGKIQFS---DXDYVDXWKAMEPLXKEGLVXSIGV 591 GK + + W+AME L G+V +IGV Sbjct: 136 TVKIGPDGKYVINKALTENPEPTWRAMEELVDSGIVKAIGV 176 Score = 33.5 bits (73), Expect = 7.8 Identities = 15/31 (48%), Positives = 22/31 (70%), Gaps = 1/31 (3%) Frame = +3 Query: 594 NFNSKQLERLLQXATVKPVVNQVECHP-LPH 683 N+ L++LL+ A +KP VNQ+E HP LP+ Sbjct: 178 NWTIPGLKQLLEFARIKPAVNQIEIHPFLPN 208 >UniRef50_P28475 Cluster: NADP-dependent D-sorbitol-6-phosphate dehydrogenase; n=71; Magnoliophyta|Rep: NADP-dependent D-sorbitol-6-phosphate dehydrogenase - Malus domestica (Apple) (Malus sylvestris) Length = 310 Score = 122 bits (295), Expect = 1e-26 Identities = 63/159 (39%), Positives = 91/159 (57%), Gaps = 4/159 (2%) Frame = +1 Query: 127 VTFNNGESIPVFGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIK 306 VT ++G +PV GLG W+ + E+ + + +AI IGYRH DCA Y +E +VGEA+ K Sbjct: 4 VTLSSGYEMPVIGLGLWRLEKDELKEVILNAIKIGYRHFDCAAHYKSEADVGEALAEAFK 63 Query: 307 EGVVTREDLFITSKLWNTFHRPDLVXGXLQETLDNLNVQYLDLYLIHWPQAYKEDGSLFP 486 G+V RE+LFIT+K+WN+ H V + +L+ L + YLDLYL+H+P K + Sbjct: 64 TGLVKREELFITTKIWNSDH--GHVVEACKNSLEKLQIDYLDLYLVHYPMPTKHNAIGKT 121 Query: 487 TXQSGKIQFSDXDYV----DXWKAMEPLXKEGLVXSIGV 591 G+ + D D W+ ME GLV SIG+ Sbjct: 122 ASLLGEDKVLDIDVTISLQQTWEGMEKTVSLGLVRSIGL 160 >UniRef50_Q6CFG7 Cluster: Yarrowia lipolytica chromosome B of strain CLIB122 of Yarrowia lipolytica; n=9; Ascomycota|Rep: Yarrowia lipolytica chromosome B of strain CLIB122 of Yarrowia lipolytica - Yarrowia lipolytica (Candida lipolytica) Length = 337 Score = 122 bits (294), Expect = 1e-26 Identities = 67/158 (42%), Positives = 92/158 (58%), Gaps = 4/158 (2%) Frame = +1 Query: 130 TFNNGESIPVFGLGTWKSKPGEVTQAVKDAI-DIGYRHIDCAYVYGNEKEVGEAITSKIK 306 T NNG++IP GLGTWKS EV AV+ A+ + GYRHID A+ Y NE VG I ++ Sbjct: 35 TLNNGKTIPAIGLGTWKSTTEEVAGAVECALTEGGYRHIDTAFNYRNEDAVGLGIKRAME 94 Query: 307 EGVVTREDLFITSKLWNTFHRPDLVXGXLQETLDNLNVQYLDLYLIHWPQAYKEDGS--L 480 +G V RED+F+T+K+W T+H D V L +L+ L + Y+D+ LIHWP +G+ + Sbjct: 95 KG-VKREDIFVTTKIWVTYH--DRVEENLDMSLERLGLDYVDMLLIHWPVPLNPNGNDPV 151 Query: 481 FPTXQSGKIQFSD-XDYVDXWKAMEPLXKEGLVXSIGV 591 +P G + WK ME + K G SIGV Sbjct: 152 YPLRPDGSRDIDESGSQPKTWKQMEAVLKTGKTKSIGV 189 Score = 36.7 bits (81), Expect = 0.83 Identities = 19/34 (55%), Positives = 21/34 (61%) Frame = +3 Query: 594 NFNSKQLERLLQXATVKPVVNQVECHPLPHQKXL 695 NF+ LE LL+ A V P VNQVE HPL Q L Sbjct: 191 NFSIPYLEELLKEAEVVPAVNQVELHPLLPQLEL 224 >UniRef50_P23901 Cluster: Aldose reductase; n=9; Poaceae|Rep: Aldose reductase - Hordeum vulgare (Barley) Length = 320 Score = 122 bits (294), Expect = 1e-26 Identities = 65/152 (42%), Positives = 93/152 (61%), Gaps = 1/152 (0%) Frame = +1 Query: 139 NGESIPVFGLGTWKSKPGEVTQAVKDAI-DIGYRHIDCAYVYGNEKEVGEAITSKIKEGV 315 +G ++P GLGTW++ + +V+ AI + GYRH+D A YG EKEVG+ + + ++ G+ Sbjct: 20 SGHAMPAVGLGTWRAG-SDTAHSVRTAITEAGYRHVDTAAEYGVEKEVGKGLKAAMEAGI 78 Query: 316 VTREDLFITSKLWNTFHRPDLVXGXLQETLDNLNVQYLDLYLIHWPQAYKEDGSLFPTXQ 495 R+DLF+TSK+W T P+ V L+ TL +L + Y+DLY IHWP K DG+ P Sbjct: 79 -DRKDLFVTSKIWCTNLAPERVRPALENTLKDLQLDYIDLYHIHWPFRLK-DGAHMPPEA 136 Query: 496 SGKIQFSDXDYVDXWKAMEPLXKEGLVXSIGV 591 ++F D WK ME L K+GLV IGV Sbjct: 137 GEVLEF---DMEGVWKEMENLVKDGLVKDIGV 165 >UniRef50_Q17DN1 Cluster: Aldo-keto reductase; n=1; Aedes aegypti|Rep: Aldo-keto reductase - Aedes aegypti (Yellowfever mosquito) Length = 284 Score = 122 bits (293), Expect = 2e-26 Identities = 62/113 (54%), Positives = 77/113 (68%), Gaps = 2/113 (1%) Frame = +1 Query: 106 MAPKIPVVTFNNGESIPVFGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGE 285 M+PK P+V NNG +PV GLGTW SK GE +A+K AID GYRHID AY Y NEKEVGE Sbjct: 1 MSPKAPMVKLNNGLEMPVLGLGTWLSKEGEGVEAIKAAIDAGYRHIDTAYFYQNEKEVGE 60 Query: 286 AITSKIKEGVVTREDLFITSKL--WNTFHRPDLVXGXLQETLDNLNVQYLDLY 438 AI +KI+EGVV REDLF+T+K W+T +L+ L +V Y+D + Sbjct: 61 AIRAKIEEGVVCREDLFVTTKFIDWDT---KNLMPYDADGKLQFSDVDYIDTW 110 Score = 53.6 bits (123), Expect = 7e-06 Identities = 24/39 (61%), Positives = 27/39 (69%) Frame = +1 Query: 475 SLFPTXQSGKIQFSDXDYVDXWKAMEPLXKEGLVXSIGV 591 +L P GK+QFSD DY+D WKAME L K G V SIGV Sbjct: 89 NLMPYDADGKLQFSDVDYIDTWKAMEKLLKTGKVKSIGV 127 Score = 44.8 bits (101), Expect = 0.003 Identities = 19/34 (55%), Positives = 25/34 (73%) Frame = +3 Query: 594 NFNSKQLERLLQXATVKPVVNQVECHPLPHQKXL 695 NFNS+Q+ RLL +KPV NQVEC+P +Q+ L Sbjct: 129 NFNSEQITRLLAECEIKPVTNQVECNPSLNQRKL 162 >UniRef50_UPI0000D9A956 Cluster: PREDICTED: similar to aldo-keto reductase family 1, member B10, partial; n=1; Macaca mulatta|Rep: PREDICTED: similar to aldo-keto reductase family 1, member B10, partial - Macaca mulatta Length = 275 Score = 121 bits (291), Expect = 3e-26 Identities = 61/102 (59%), Positives = 70/102 (68%), Gaps = 6/102 (5%) Frame = +1 Query: 178 KSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIKEGVVTREDLFITSK--- 348 KS G+V +AVK AID GYRHIDCAYVY NE EVGEAI KI+E V REDLFI SK Sbjct: 42 KSPLGKVKEAVKVAIDAGYRHIDCAYVYQNEHEVGEAIQEKIQEQAVKREDLFIVSKVHM 101 Query: 349 ---LWNTFHRPDLVXGXLQETLDNLNVQYLDLYLIHWPQAYK 465 LW TF LV ++TL +L + YLD+YLIHWPQ +K Sbjct: 102 AHWLWTTFFERPLVRKAFEKTLKDLKLSYLDVYLIHWPQGFK 143 Score = 37.5 bits (83), Expect = 0.48 Identities = 19/36 (52%), Positives = 23/36 (63%), Gaps = 2/36 (5%) Frame = +3 Query: 594 NFNSKQLERLLQXATVK--PVVNQVECHPLPHQKXL 695 NFN Q+E+LL +K PV NQVECHP Q+ L Sbjct: 161 NFNHFQIEKLLNKPGLKYKPVTNQVECHPYLTQEKL 196 >UniRef50_Q17G72 Cluster: Aldo-keto reductase; n=9; Endopterygota|Rep: Aldo-keto reductase - Aedes aegypti (Yellowfever mosquito) Length = 316 Score = 121 bits (291), Expect = 3e-26 Identities = 60/155 (38%), Positives = 91/155 (58%) Frame = +1 Query: 127 VTFNNGESIPVFGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIK 306 +TF NG ++P G GTW++ EV +A+ +A++ GYRHID A VY NEK +G+ + + Sbjct: 7 ITFENGTTMPALGFGTWRASDEEVEKALNEALEAGYRHIDTAPVYLNEKTIGKVLKEWMD 66 Query: 307 EGVVTREDLFITSKLWNTFHRPDLVXGXLQETLDNLNVQYLDLYLIHWPQAYKEDGSLFP 486 G VTR++LFI +KL R V L+ +LD+L ++Y+DLY +H P E F Sbjct: 67 AGKVTRDELFIVTKLPPHGTRASTVEKFLKNSLDDLQLEYVDLYHVHVPFTVPEVDGPFL 126 Query: 487 TXQSGKIQFSDXDYVDXWKAMEPLXKEGLVXSIGV 591 + + D+V WKAME + + GL +IG+ Sbjct: 127 VEDGLIVLETTTDHVALWKAMEEVYEAGLARNIGL 161 >UniRef50_P14065 Cluster: Protein GCY; n=13; Saccharomycetales|Rep: Protein GCY - Saccharomyces cerevisiae (Baker's yeast) Length = 312 Score = 121 bits (291), Expect = 3e-26 Identities = 65/165 (39%), Positives = 98/165 (59%), Gaps = 9/165 (5%) Frame = +1 Query: 124 VVTFNNGESIPVFGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKI 303 +++ N G IP GLGTW+SK + +AV A+ GYRHID A +Y NE +VG+A I Sbjct: 11 ILSLNTGAQIPQIGLGTWQSKENDAYKAVLTALKDGYRHIDTAAIYRNEDQVGQA----I 66 Query: 304 KEGVVTREDLFITSKLWNT-FHRPDLVXGXLQETLDNLNVQYLDLYLIHWP----QAY-- 462 K+ V RE++F+T+KLW T H P++ L ++L L + Y+DLYL+HWP AY Sbjct: 67 KDSGVPREEIFVTTKLWCTQHHEPEVA---LDQSLKRLGLDYVDLYLMHWPARLDPAYIK 123 Query: 463 KEDGSLFPTXQSGK--IQFSDXDYVDXWKAMEPLXKEGLVXSIGV 591 ED PT + G + ++ +++ W+ M+ L K G ++GV Sbjct: 124 NEDILSVPTKKDGSRAVDITNWNFIKTWELMQELPKTGKTKAVGV 168 >UniRef50_Q23320 Cluster: Putative uncharacterized protein; n=4; Caenorhabditis|Rep: Putative uncharacterized protein - Caenorhabditis elegans Length = 320 Score = 120 bits (290), Expect = 4e-26 Identities = 62/162 (38%), Positives = 92/162 (56%) Frame = +1 Query: 106 MAPKIPVVTFNNGESIPVFGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGE 285 M+ K+P+ T +NG +P GLGTW+ E +++A+ GYRHID A +Y NE ++G+ Sbjct: 1 MSSKVPIFTLSNGVLMPSIGLGTWQMTGEEGKTVIRNAVLAGYRHIDTATLYQNEHQIGD 60 Query: 286 AITSKIKEGVVTREDLFITSKLWNTFHRPDLVXGXLQETLDNLNVQYLDLYLIHWPQAYK 465 A+ EG++ RED+FIT+K + PD+V L+ +L L + Y+DLYL H P + K Sbjct: 61 ALAELFAEGILKREDIFITTKAFCHEVAPDVVEEALRNSLKRLRLDYVDLYLAHIPASTK 120 Query: 466 EDGSLFPTXQSGKIQFSDXDYVDXWKAMEPLXKEGLVXSIGV 591 +DGS SD D W+ E + GL +IGV Sbjct: 121 DDGSF----------RSDVKVEDIWRGFEKVYGLGLTKAIGV 152 >UniRef50_Q6NII7 Cluster: Putative oxidoreductase; n=2; Corynebacterium|Rep: Putative oxidoreductase - Corynebacterium diphtheriae Length = 290 Score = 120 bits (289), Expect = 5e-26 Identities = 51/116 (43%), Positives = 73/116 (62%) Frame = +1 Query: 118 IPVVTFNNGESIPVFGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITS 297 IP +T N+G +P G GT+K + + +AV+ AI++GYRHID A +Y NE+EVG A+ Sbjct: 11 IPTITLNDGTEMPAIGFGTYKLREQDAYRAVRSAIEVGYRHIDTASLYKNEEEVGRAVAD 70 Query: 298 KIKEGVVTREDLFITSKLWNTFHRPDLVXGXLQETLDNLNVQYLDLYLIHWPQAYK 465 I G V R++LFIT+K+WN H L QE+L L + Y+D ++HWP K Sbjct: 71 AITAGEVARDELFITTKVWNDMHGDQLTQRSFQESLHRLGLDYIDCCMVHWPWPQK 126 >UniRef50_A1D4E3 Cluster: D-xylose reductase (Xyl1), putative; n=5; Pezizomycotina|Rep: D-xylose reductase (Xyl1), putative - Neosartorya fischeri (strain ATCC 1020 / DSM 3700 / NRRL 181)(Aspergillus fischerianus (strain ATCC 1020 / DSM 3700 / NRRL 181)) Length = 321 Score = 119 bits (287), Expect = 9e-26 Identities = 62/162 (38%), Positives = 88/162 (54%), Gaps = 5/162 (3%) Frame = +1 Query: 121 PVVTFNNGESIPVFGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSK 300 P N+G +P+ G G WK + AI GYR D A YGNE E G+ + Sbjct: 4 PSTKLNSGYDMPLVGFGLWKVNNETCADQIYHAIKAGYRLFDGACDYGNEVEAGKGVARA 63 Query: 301 IKEGVVTREDLFITSKLWNTFHRPDLVXGXLQETLDNLNVQYLDLYLIHWPQA--YKEDG 474 I+EG+V REDLFI SKLWN+FH D V ++ L + + Y DL+++H+P A Y + Sbjct: 64 IQEGIVKREDLFIVSKLWNSFHDGDRVEPICRKQLADWGLDYFDLFIVHFPIALKYVDPA 123 Query: 475 SLFP---TXQSGKIQFSDXDYVDXWKAMEPLXKEGLVXSIGV 591 +P ++ K++FS+ + W AME L + L SIGV Sbjct: 124 VRYPPGWLSENNKLEFSNASIQETWTAMESLVDKKLARSIGV 165 >UniRef50_P26690 Cluster: NAD(P)H-dependent 6'-deoxychalcone synthase; n=3; Papilionoideae|Rep: NAD(P)H-dependent 6'-deoxychalcone synthase - Glycine max (Soybean) Length = 315 Score = 119 bits (287), Expect = 9e-26 Identities = 65/166 (39%), Positives = 97/166 (58%), Gaps = 5/166 (3%) Frame = +1 Query: 109 APKIPVVTFNNGES---IPVFGLGTWK--SKPGEVTQAVKDAIDIGYRHIDCAYVYGNEK 273 A +IP + F N + +PV G+G+ + + +A+ +A+ GYRH D A YG+E+ Sbjct: 4 AIEIPTIVFPNSSAQQRMPVVGMGSAPDFTCKKDTKEAIIEAVKQGYRHFDTAAAYGSEQ 63 Query: 274 EVGEAITSKIKEGVVTREDLFITSKLWNTFHRPDLVXGXLQETLDNLNVQYLDLYLIHWP 453 +GEA+ I G+V+R+DLF+TSKLW T + P LV L+++L L ++YLDLYLIHWP Sbjct: 64 ALGEALKEAIHLGLVSRQDLFVTSKLWVTENHPHLVLPALRKSLKTLQLEYLDLYLIHWP 123 Query: 454 QAYKEDGSLFPTXQSGKIQFSDXDYVDXWKAMEPLXKEGLVXSIGV 591 + + FP + F D W++ME K GL +IGV Sbjct: 124 LSSQPGKFSFPIEVEDLLPF---DVKGVWESMEECQKLGLTKAIGV 166 Score = 35.9 bits (79), Expect = 1.5 Identities = 17/34 (50%), Positives = 24/34 (70%) Frame = +3 Query: 594 NFNSKQLERLLQXATVKPVVNQVECHPLPHQKXL 695 NF+ K+L+ LL AT++PVV+QVE + QK L Sbjct: 168 NFSVKKLQNLLSVATIRPVVDQVEMNLAWQQKKL 201 >UniRef50_P22045 Cluster: Probable reductase; n=101; cellular organisms|Rep: Probable reductase - Leishmania major Length = 284 Score = 119 bits (286), Expect = 1e-25 Identities = 70/157 (44%), Positives = 92/157 (58%), Gaps = 1/157 (0%) Frame = +1 Query: 124 VVTFNNGESIPVFGLGTWKSKPGEVTQ-AVKDAIDIGYRHIDCAYVYGNEKEVGEAITSK 300 +VT +NG +P FGLG W+S GEVT+ AV A+ GYRHID A +Y NE+ VG + Sbjct: 8 MVTLSNGVKMPQFGLGVWQSPAGEVTENAVNWALCAGYRHIDTAAIYKNEESVGAGL--- 64 Query: 301 IKEGVVTREDLFITSKLWNTFHRPDLVXGXLQETLDNLNVQYLDLYLIHWPQAYKEDGSL 480 + V RED+FIT+KLWNT + +E+ L V Y+DLYLIHWP+ K+ S Sbjct: 65 -RASGVPREDVFITTKLWNTEQGYESTLAAFEESRQKLGVDYIDLYLIHWPRG-KDILS- 121 Query: 481 FPTXQSGKIQFSDXDYVDXWKAMEPLXKEGLVXSIGV 591 + GK Y+D W+A E L KE V +IGV Sbjct: 122 ----KEGK------KYLDSWRAFEQLYKEKKVRAIGV 148 Score = 37.9 bits (84), Expect = 0.36 Identities = 18/34 (52%), Positives = 22/34 (64%) Frame = +3 Query: 594 NFNSKQLERLLQXATVKPVVNQVECHPLPHQKXL 695 NF+ LE +L TV P+VNQVE HPL +Q L Sbjct: 150 NFHIHHLEDVLAMCTVTPMVNQVELHPLNNQADL 183 >UniRef50_A7CWF9 Cluster: Aldehyde reductase; n=2; Bacteria|Rep: Aldehyde reductase - Opitutaceae bacterium TAV2 Length = 347 Score = 117 bits (282), Expect = 4e-25 Identities = 63/163 (38%), Positives = 88/163 (53%), Gaps = 5/163 (3%) Frame = +1 Query: 115 KIPVVTFNNGESIPVFGLGTWKSK---PGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGE 285 KIP T +G +P G+GT+ S PGEV +V A ++GYRH DCA VY NE+E+G Sbjct: 15 KIPQRTLASGARMPAIGMGTFGSDHAAPGEVAASVYAAAELGYRHFDCAAVYSNEREIGA 74 Query: 286 AITSKIKEGV-VTREDLFITSKLWNTFHRPDLVXGXLQETLDNLNVQYLDLYLIHWP-QA 459 + + REDL+ITSKLWN H V +++L +L + YLDLYLIHWP Sbjct: 75 TFRRILTSNTGIRREDLWITSKLWNDKHAEADVIPAFEKSLRDLGLDYLDLYLIHWPFPN 134 Query: 460 YKEDGSLFPTXQSGKIQFSDXDYVDXWKAMEPLXKEGLVXSIG 588 + G + + +++ W+ +E L GLV IG Sbjct: 135 FHPPGCDVSSRSPDARPYIHAEFMKTWRQLETLHDRGLVRHIG 177 >UniRef50_Q03TW0 Cluster: Aldo/keto reductase of diketogulonate reductase family; n=1; Lactobacillus brevis ATCC 367|Rep: Aldo/keto reductase of diketogulonate reductase family - Lactobacillus brevis (strain ATCC 367 / JCM 1170) Length = 293 Score = 117 bits (281), Expect = 5e-25 Identities = 70/159 (44%), Positives = 87/159 (54%), Gaps = 1/159 (0%) Frame = +1 Query: 118 IPVVTFNNGESIPVFGLGTWKSKPGEVTQ-AVKDAIDIGYRHIDCAYVYGNEKEVGEAIT 294 IP + NNG IP GLG ++ E T+ A+K A+ GYRHID A YGNE+ VGEAI Sbjct: 11 IPDLPMNNGHQIPQLGLGVFQVDNAEDTKNAIKWALAAGYRHIDTAAYYGNEQWVGEAI- 69 Query: 295 SKIKEGVVTREDLFITSKLWNTFHRPDLVXGXLQETLDNLNVQYLDLYLIHWPQAYKEDG 474 +E V R+ +F+TSKLWN+ D QETLD L + YLDLYLIHWP Sbjct: 70 ---RESDVPRDQIFVTSKLWNSVRGYDETQAAFQETLDKLGLDYLDLYLIHWPA------ 120 Query: 475 SLFPTXQSGKIQFSDXDYVDXWKAMEPLXKEGLVXSIGV 591 Y+D W+AME L K G + +IGV Sbjct: 121 ---------------PGYLDSWRAMEDLYKAGKIKNIGV 144 Score = 38.3 bits (85), Expect = 0.27 Identities = 17/42 (40%), Positives = 24/42 (57%) Frame = +3 Query: 594 NFNSKQLERLLQXATVKPVVNQVECHPLPHQKXLXSSVRLAG 719 NFN Q+ +L TVKPVV+Q+E HP Q + + + G Sbjct: 146 NFNQTQMADILAHGTVKPVVDQIETHPYFQQNDMHAYLESQG 187 >UniRef50_UPI00015B4B22 Cluster: PREDICTED: similar to GA15457-PA; n=1; Nasonia vitripennis|Rep: PREDICTED: similar to GA15457-PA - Nasonia vitripennis Length = 388 Score = 116 bits (280), Expect = 6e-25 Identities = 65/162 (40%), Positives = 91/162 (56%), Gaps = 1/162 (0%) Frame = +1 Query: 109 APKIPVVTFNNGESIPVFGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEA 288 A + + ++G IP GLGT K E+ A+ A++ GYRHID A+ Y NE +G+ Sbjct: 20 AQAVEKLKLSSGHEIPAVGLGTSTIKLDEMDNAISSALENGYRHIDTAFSYDNEAAIGKI 79 Query: 289 ITSKIKEGVVTREDLFITSKLWNTFHRPDLVXGXLQETLDNLNVQYLDLYLIHWPQAYKE 468 + +G RED+FITSKL + +RP V L+ +L +L + Y+D+YLIH P A KE Sbjct: 80 LKKWFDKG-GKREDIFITSKLPSQGNRPQSVETYLKRSLKDLGLDYVDMYLIHTPFAVKE 138 Query: 469 DGSL-FPTXQSGKIQFSDXDYVDXWKAMEPLXKEGLVXSIGV 591 +L + G F D D+ WKAME KEG SIG+ Sbjct: 139 GENLSSKQDKDGNDLFDDVDHKALWKAMERQVKEGRAKSIGL 180 >UniRef50_Q0CLQ2 Cluster: Putative uncharacterized protein; n=1; Aspergillus terreus NIH2624|Rep: Putative uncharacterized protein - Aspergillus terreus (strain NIH 2624) Length = 301 Score = 116 bits (280), Expect = 6e-25 Identities = 72/174 (41%), Positives = 93/174 (53%), Gaps = 22/174 (12%) Frame = +1 Query: 136 NNGESIPVFGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIKEGV 315 ++G +P GLGTW SKP EV AV+ A+ +GYRHID A Y NE EVG K+ Sbjct: 10 SSGYDMPAVGLGTWLSKPHEVENAVETALRLGYRHIDAAACYLNENEVGNG----WKKSG 65 Query: 316 VTREDLFITSKLWNTFHRPDLVXGXLQETLDNLNVQYLDLYL------------------ 441 V R+ +FITSKLWNT H PD V + +TL +L YLDLYL Sbjct: 66 VPRDQIFITSKLWNTHHHPDHVEEAVNKTLKDLQTDYLDLYLVFPSLLVLIHDLLSLLTN 125 Query: 442 --IHWPQAYKE-DGSLFPTXQ-SGKIQFSDXDYVDXWKAMEPLXKEGLVXSIGV 591 IHWP A++ + +L P S + + ++ D W A+E L G V SIGV Sbjct: 126 NKIHWPVAFEHTNETLTPIDPVSKRFRLANIPIADTWAALEKLVDAGKVRSIGV 179 Score = 36.3 bits (80), Expect = 1.1 Identities = 15/34 (44%), Positives = 21/34 (61%) Frame = +3 Query: 594 NFNSKQLERLLQXATVKPVVNQVECHPLPHQKXL 695 NF +++E LL+ A + P VNQ+E HP Q L Sbjct: 181 NFTIEKIEELLKTARIPPAVNQIEAHPYLQQPAL 214 >UniRef50_Q01J82 Cluster: OSIGBa0152K17.5 protein; n=28; Magnoliophyta|Rep: OSIGBa0152K17.5 protein - Oryza sativa (Rice) Length = 323 Score = 116 bits (279), Expect = 9e-25 Identities = 60/154 (38%), Positives = 89/154 (57%), Gaps = 4/154 (2%) Frame = +1 Query: 142 GESIPVFGLGTWKS---KPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIKEG 312 G +P G+GT S P A A+++G+RH D A +YG E +GEAI + G Sbjct: 14 GRPMPAVGVGTADSAATSPETKRGAALAALEVGFRHFDTAALYGTEAPLGEAIAEATRRG 73 Query: 313 VV-TREDLFITSKLWNTFHRPDLVXGXLQETLDNLNVQYLDLYLIHWPQAYKEDGSLFPT 489 +V +RE++F+T+KLW T P LV L+E+L NL ++Y+DLYL+HWP + K + P Sbjct: 74 LVASREEVFVTTKLWCTQCHPGLVLPSLRESLRNLQMEYVDLYLVHWPISVKPGPPMLPV 133 Query: 490 XQSGKIQFSDXDYVDXWKAMEPLXKEGLVXSIGV 591 + + F D+ W+AME + GL +IGV Sbjct: 134 KREDAVPF---DFEGVWRAMEECHRLGLAKAIGV 164 Score = 38.3 bits (85), Expect = 0.27 Identities = 16/32 (50%), Positives = 23/32 (71%) Frame = +3 Query: 594 NFNSKQLERLLQXATVKPVVNQVECHPLPHQK 689 NF +K L++LL AT+ P VNQVE +P+ Q+ Sbjct: 166 NFTTKHLDKLLAVATIPPAVNQVEMNPVWQQR 197 >UniRef50_A6W8E7 Cluster: 2,5-didehydrogluconate reductase; n=3; Actinomycetales|Rep: 2,5-didehydrogluconate reductase - Kineococcus radiotolerans SRS30216 Length = 289 Score = 116 bits (278), Expect = 1e-24 Identities = 63/161 (39%), Positives = 89/161 (55%) Frame = +1 Query: 109 APKIPVVTFNNGESIPVFGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEA 288 A +P + N+G IP G G ++ +PG+ QAVK A+D+GYRHID A +YGNE EV + Sbjct: 9 AMTVPTILLNDGREIPQLGFGVFQIEPGDTAQAVKTALDLGYRHIDTAQMYGNEAEVAQG 68 Query: 289 ITSKIKEGVVTREDLFITSKLWNTFHRPDLVXGXLQETLDNLNVQYLDLYLIHWPQAYKE 468 I + V R+++++TSKL N FH PD + ++++ L +DLYLIHWP Sbjct: 69 IA----DSGVPRDEIWVTSKLNNGFHEPDAARKAVDDSVEKLRGP-IDLYLIHWP----- 118 Query: 469 DGSLFPTXQSGKIQFSDXDYVDXWKAMEPLXKEGLVXSIGV 591 PT G D+V WK +E G + SIGV Sbjct: 119 ----LPTLYGG-------DFVSTWKVLEEARAAGKLRSIGV 148 Score = 37.5 bits (83), Expect = 0.48 Identities = 16/27 (59%), Positives = 18/27 (66%) Frame = +3 Query: 594 NFNSKQLERLLQXATVKPVVNQVECHP 674 NF L+RL Q ATV P VNQ+E HP Sbjct: 150 NFQVNHLQRLAQEATVVPAVNQIEVHP 176 >UniRef50_A6RKL9 Cluster: Putative uncharacterized protein; n=3; Sclerotiniaceae|Rep: Putative uncharacterized protein - Botryotinia fuckeliana B05.10 Length = 360 Score = 116 bits (278), Expect = 1e-24 Identities = 59/128 (46%), Positives = 79/128 (61%), Gaps = 5/128 (3%) Frame = +1 Query: 109 APKIPVVTFNNGESI--PVFGLGTWKSK--PGEVTQAVKDAIDIGYRHIDCAYVYGNEKE 276 A + P+ + +SI P+ G GTW K P T+AV AI+IGYR IDCA VYGNE Sbjct: 23 AEQHPIAPPSQKQSISQPLIGFGTWNLKVSPENTTEAVAYAIEIGYRQIDCAAVYGNEVA 82 Query: 277 VGEAITSKIKEGVVTREDLFITSKLWNTFHRP-DLVXGXLQETLDNLNVQYLDLYLIHWP 453 VG I +K + RED+++TSKLWN H + V L +TL +L ++YLDLYLIHWP Sbjct: 83 VGRGIEEGLKRAGLKREDIWVTSKLWNDHHGSYENVEKGLNQTLQDLGLEYLDLYLIHWP 142 Query: 454 QAYKEDGS 477 + +G+ Sbjct: 143 IGFSSNGA 150 >UniRef50_Q03PG5 Cluster: Aldo/keto reductase of diketogulonate reductase family; n=1; Lactobacillus brevis ATCC 367|Rep: Aldo/keto reductase of diketogulonate reductase family - Lactobacillus brevis (strain ATCC 367 / JCM 1170) Length = 268 Score = 114 bits (275), Expect = 3e-24 Identities = 63/152 (41%), Positives = 86/152 (56%) Frame = +1 Query: 136 NNGESIPVFGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIKEGV 315 +NG +IP+ G GT+ +V A+K A+D GYRH+DCA++YGNE VGEA IK Sbjct: 7 SNGVTIPMLGFGTYLIDSKDVPAAIKTALDAGYRHLDCAHIYGNEPAVGEA----IKASG 62 Query: 316 VTREDLFITSKLWNTFHRPDLVXGXLQETLDNLNVQYLDLYLIHWPQAYKEDGSLFPTXQ 495 + R DLFITSK+WN D +TL +L + YLDLYLIHWP ++D L Sbjct: 63 IDRSDLFITSKVWNADQGYDKTLAAFDQTLSDLQLDYLDLYLIHWPN--EDDFEL----- 115 Query: 496 SGKIQFSDXDYVDXWKAMEPLXKEGLVXSIGV 591 +D W+ +E L ++ V +IGV Sbjct: 116 ----------TLDTWRVLETLYQQKKVRAIGV 137 Score = 39.1 bits (87), Expect = 0.16 Identities = 16/34 (47%), Positives = 24/34 (70%) Frame = +3 Query: 594 NFNSKQLERLLQXATVKPVVNQVECHPLPHQKXL 695 NF+ QL+++ + ATVKP++NQ+E HP Q L Sbjct: 139 NFSEDQLKQVFEMATVKPMINQIERHPYKVQADL 172 >UniRef50_Q01HB5 Cluster: OSIGBa0136O08-OSIGBa0153H12.9 protein; n=4; Oryza sativa|Rep: OSIGBa0136O08-OSIGBa0153H12.9 protein - Oryza sativa (Rice) Length = 337 Score = 114 bits (275), Expect = 3e-24 Identities = 63/164 (38%), Positives = 89/164 (54%), Gaps = 3/164 (1%) Frame = +1 Query: 109 APKIPVVTFNNGESIPVFGLGTWKSKP-GEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGE 285 A +P VT N+G ++PV G GT S P ++ + A+ +GYRH+D A VYG E VG Sbjct: 17 ATAVPCVTLNSGHAMPVLGFGTGSSTPPADLAATIAHAVRLGYRHLDTAAVYGTEGAVGA 76 Query: 286 AITSKIKEGVV-TREDLFITSKLWNTFHRPDLVXGXLQETLDNLNVQYLDLYLIHWPQAY 462 A+ ++ G V +R +LF+T+KL P V L+E+L L + Y+DL+LIHWP A Sbjct: 77 AVAEAVRCGAVASRGELFVTTKLSMADAHPPRVVAALRESLSRLGLDYVDLFLIHWPVAI 136 Query: 463 -KEDGSLFPTXQSGKIQFSDXDYVDXWKAMEPLXKEGLVXSIGV 591 K+D + T D W+ ME + GL SIGV Sbjct: 137 GKKDAAGELTWDDLSRGLVPFDMEGVWRGMEECHRLGLARSIGV 180 >UniRef50_A5E082 Cluster: GCY protein; n=4; Saccharomycetales|Rep: GCY protein - Lodderomyces elongisporus (Yeast) (Saccharomyces elongisporus) Length = 295 Score = 114 bits (275), Expect = 3e-24 Identities = 64/156 (41%), Positives = 91/156 (58%), Gaps = 2/156 (1%) Frame = +1 Query: 130 TFNNGESIPVFGLGTWKSKPGEVT-QAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIK 306 T NNG IP GLGTW + + +A A+ GY+HID A YGNE +VG AI Sbjct: 13 TLNNGLKIPAIGLGTWLADEEDAAYKATLTALKNGYKHIDTAAAYGNEDQVGRAIA---- 68 Query: 307 EGVVTREDLFITSKLWNTFHRPDLVXGXLQETLDNLNVQYLDLYLIHWPQAYKEDGSLFP 486 + V+R+++F+T+KLWN H+ G L E+L L ++Y+DLYLIHWP S+ P Sbjct: 69 DSGVSRDEIFVTTKLWNDQHKDP--EGALDESLKKLGLEYVDLYLIHWPL------SVDP 120 Query: 487 TXQSGKIQFSDXDYVDXWKAMEPLXKEG-LVXSIGV 591 + + D D+VD W+ ++ + KEG V +IGV Sbjct: 121 KTEK---PYDDYDFVDTWRNLQKIYKEGKKVKAIGV 153 Score = 37.9 bits (84), Expect = 0.36 Identities = 18/36 (50%), Positives = 24/36 (66%), Gaps = 2/36 (5%) Frame = +3 Query: 594 NFNSKQLERLL--QXATVKPVVNQVECHPLPHQKXL 695 NFN K+L++LL + V PV+NQ+E HPL Q L Sbjct: 155 NFNKKKLDKLLNSEGVNVVPVINQIEAHPLLTQPDL 190 >UniRef50_UPI00015B40FA Cluster: PREDICTED: similar to CG2767-PA; n=2; Nasonia vitripennis|Rep: PREDICTED: similar to CG2767-PA - Nasonia vitripennis Length = 356 Score = 114 bits (274), Expect = 3e-24 Identities = 61/158 (38%), Positives = 94/158 (59%), Gaps = 3/158 (1%) Frame = +1 Query: 127 VTFNNGESIPVFGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIK 306 + ++G +P+ GLGTW+ P + AV A++ GYRHID A+ YGNE+ +G+ + Sbjct: 28 IKLSSGHDMPMIGLGTWQMPPEAIEVAVTAALESGYRHIDTAFTYGNEEAIGKTLKKWFD 87 Query: 307 EGVVTREDLFITSKLWNTFHRPDLVXGXLQETLDNLNVQYLDLYLIHWPQAYKEDGSLF- 483 +G REDLFIT+KL R + V L+ +L+ L ++Y+++YLIH P A+ +D + Sbjct: 88 KG-GKREDLFITTKLPPIGMRAEYVESYLKLSLEKLGLEYVNMYLIHKPFAFVKDKYKYE 146 Query: 484 PTXQ-SGKIQF-SDXDYVDXWKAMEPLXKEGLVXSIGV 591 P G + +D D+V W+AME K G V SIG+ Sbjct: 147 PALNPDGSVVLDTDTDHVAIWRAMEKQVKAGRVRSIGL 184 >UniRef50_Q8F1G4 Cluster: Aldehyde reductase; n=8; Bacteria|Rep: Aldehyde reductase - Leptospira interrogans Length = 278 Score = 113 bits (273), Expect = 5e-24 Identities = 55/123 (44%), Positives = 78/123 (63%), Gaps = 1/123 (0%) Frame = +1 Query: 100 NKMAPKIPVVTFNNGESIPVFGLGTWKSKPG-EVTQAVKDAIDIGYRHIDCAYVYGNEKE 276 NK P + NNG S+P+ GLG WK+K G E +AV +A++ GYRHID A +Y NE + Sbjct: 3 NKENPLKQTIMLNNGISMPILGLGVWKTKSGKECKEAVLNALEAGYRHIDTARIYDNEVD 62 Query: 277 VGEAITSKIKEGVVTREDLFITSKLWNTFHRPDLVXGXLQETLDNLNVQYLDLYLIHWPQ 456 VG+AI +E + R+++FIT+KLWN D L+ +LD L + ++DLYLIH+P Sbjct: 63 VGQAI----RESGIPRKEIFITTKLWNADQGSDKTRKALENSLDRLGIDFVDLYLIHFPV 118 Query: 457 AYK 465 K Sbjct: 119 TSK 121 >UniRef50_Q7XY49 Cluster: Mannose 6-phosphate reductase; n=1; Griffithsia japonica|Rep: Mannose 6-phosphate reductase - Griffithsia japonica (Red alga) Length = 174 Score = 113 bits (272), Expect = 6e-24 Identities = 54/105 (51%), Positives = 67/105 (63%) Frame = +1 Query: 130 TFNNGESIPVFGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIKE 309 T +G +P+ G GTWK+ E QAV A+ GYRHIDCA VY NE VG AI+ I Sbjct: 7 TLQSGAKMPLNGFGTWKASVEETEQAVTAALRAGYRHIDCAAVYWNEAAVGTAISKAISG 66 Query: 310 GVVTREDLFITSKLWNTFHRPDLVXGXLQETLDNLNVQYLDLYLI 444 GVV REDLFITSK+WNT H D V +++L + V Y DL+L+ Sbjct: 67 GVVKREDLFITSKVWNTCHATDKVVDSCRQSLKDHQVDYFDLFLV 111 >UniRef50_Q9HGY0 Cluster: Glycerol dehydrogenase; n=8; Saccharomycetaceae|Rep: Glycerol dehydrogenase - Zygosaccharomyces rouxii (Candida mogii) Length = 310 Score = 113 bits (272), Expect = 6e-24 Identities = 63/159 (39%), Positives = 93/159 (58%), Gaps = 7/159 (4%) Frame = +1 Query: 136 NNGESIPVFGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIKEGV 315 N G++IP GLGTW+SK E +AV +A+ GYRHID A VYGNE EVG+A I++ Sbjct: 14 NTGQTIPQVGLGTWRSKENEGYKAVIEALKAGYRHIDGAAVYGNEGEVGKA----IQDSG 69 Query: 316 VTREDLFITSKLWNTFHRPDLVXGXLQETLDNLNVQYLDLYLIHWPQAYK----EDGSLF 483 V R ++F+T+KLW T R L ++L L + Y+ LYL+HWP + +DG+LF Sbjct: 70 VPRNEIFLTTKLWCTHQRNP--QEALDQSLQRLGLDYVGLYLVHWPVPLRTENIKDGNLF 127 Query: 484 PTXQ---SGKIQFSDXDYVDXWKAMEPLXKEGLVXSIGV 591 + K + +++ W+ M+ L + G +IGV Sbjct: 128 QFAEKPDGSKDVDLEWNFIKTWELMQKLLESGKTKAIGV 166 >UniRef50_Q6C2L0 Cluster: Yarrowia lipolytica chromosome F of strain CLIB122 of Yarrowia lipolytica; n=3; Yarrowia lipolytica|Rep: Yarrowia lipolytica chromosome F of strain CLIB122 of Yarrowia lipolytica - Yarrowia lipolytica (Candida lipolytica) Length = 324 Score = 113 bits (272), Expect = 6e-24 Identities = 62/158 (39%), Positives = 94/158 (59%), Gaps = 6/158 (3%) Frame = +1 Query: 136 NNGESIPVFGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIKEGV 315 N+G SIP GLGT + G V + V AI GYRHID A++YG+E +VG+ I I E + Sbjct: 10 NDGHSIPALGLGT--ASDGNVEEVVYAAIKNGYRHIDTAFIYGSEVDVGKGIKRAIDEEL 67 Query: 316 VTREDLFITSKLWNTFHRPDLVXGXLQETLDNLNVQYLDLYLIHWPQAYKEDG----SLF 483 V RE+LF+T+K+W TF+ + V L +L +L++ Y+DL L+HWP + D +++ Sbjct: 68 VKRENLFVTTKVWPTFY--NRVSESLDISLKDLSLDYVDLLLVHWPVSLLADSDDPRAIY 125 Query: 484 PTXQSGKIQFSD--XDYVDXWKAMEPLXKEGLVXSIGV 591 G +++SD D++ +K +E G SIGV Sbjct: 126 LVNTDGSVRYSDSLDDWITTYKQIEEEKLSGRTKSIGV 163 >UniRef50_P70883 Cluster: AkrI; n=1; Butyrivibrio fibrisolvens|Rep: AkrI - Butyrivibrio fibrisolvens Length = 172 Score = 113 bits (271), Expect = 8e-24 Identities = 62/156 (39%), Positives = 84/156 (53%), Gaps = 1/156 (0%) Frame = +1 Query: 127 VTFNNGESIPVFGLGTWKSKP-GEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKI 303 + NNG +IP+FG GT+K K E +V+ A+ GYRHID A Y NEK V AI + Sbjct: 8 IKLNNGTAIPMFGYGTYKIKDQNEAYNSVRLALKNGYRHIDTAAFYENEKFVANAIKDFM 67 Query: 304 KEGVVTREDLFITSKLWNTFHRPDLVXGXLQETLDNLNVQYLDLYLIHWPQAYKEDGSLF 483 +E RED+F+TSK W T D ++T++ + + YLDLYL+HWP +Y D Sbjct: 68 EESQTKREDIFVTSKAWKTELGYDKTLAAFEKTMNEMQMDYLDLYLVHWPASYAFDDDWE 127 Query: 484 PTXQSGKIQFSDXDYVDXWKAMEPLXKEGLVXSIGV 591 T + WKAM + K G V +IGV Sbjct: 128 NTNR------------QTWKAMTEIYKSGRVKAIGV 151 >UniRef50_Q5FK98 Cluster: Oxidoreductase; n=8; Lactobacillales|Rep: Oxidoreductase - Lactobacillus acidophilus Length = 285 Score = 112 bits (270), Expect = 1e-23 Identities = 62/155 (40%), Positives = 90/155 (58%), Gaps = 1/155 (0%) Frame = +1 Query: 130 TFNNGESIPVFGLGTWKSKPGEVTQ-AVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIK 306 T NNG IP+ G GTW++ GEV + +V A++ GYRHID A YGNE VG AI K Sbjct: 11 TLNNGVKIPIIGFGTWQTPDGEVAEESVLAALNCGYRHIDTASAYGNEDSVGRAIQ---K 67 Query: 307 EGVVTREDLFITSKLWNTFHRPDLVXGXLQETLDNLNVQYLDLYLIHWPQAYKEDGSLFP 486 G+ R +LFIT+KLWN+ H + + ++L +L + YLD+YLIHWP Sbjct: 68 SGI-NRHELFITTKLWNSDHGYEKTKKAIDQSLLDLKLDYLDMYLIHWPNP--------- 117 Query: 487 TXQSGKIQFSDXDYVDXWKAMEPLXKEGLVXSIGV 591 S + +++ + + W+AME + G + +IGV Sbjct: 118 --SSMRDHWAEIN-AESWRAMEEAVRAGKIRAIGV 149 >UniRef50_A6ESC0 Cluster: ARA1; n=1; unidentified eubacterium SCB49|Rep: ARA1 - unidentified eubacterium SCB49 Length = 280 Score = 112 bits (270), Expect = 1e-23 Identities = 63/153 (41%), Positives = 87/153 (56%), Gaps = 1/153 (0%) Frame = +1 Query: 136 NNGESIPVFGLGTWKSKPGEVT-QAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIKEG 312 NN +IP G GTW++ G+ A+K AID GY+HID A +Y NEK VG I KE Sbjct: 8 NNNINIPAIGFGTWQTPDGQTAINAIKTAIDAGYKHIDAAAIYKNEKGVGLGI----KEA 63 Query: 313 VVTREDLFITSKLWNTFHRPDLVXGXLQETLDNLNVQYLDLYLIHWPQAYKEDGSLFPTX 492 + R+DLF+TSK+WN + T+++L + YLDLYLIHWP A + F Sbjct: 64 NIDRKDLFVTSKVWNEQRGYENTLKAFDNTINDLQLDYLDLYLIHWPAAAHQ----FENW 119 Query: 493 QSGKIQFSDXDYVDXWKAMEPLXKEGLVXSIGV 591 + Q ++ D W AME L K+G + ++GV Sbjct: 120 K----QLNN----DTWSAMEKLYKDGKIKALGV 144 Score = 37.1 bits (82), Expect = 0.63 Identities = 16/27 (59%), Positives = 18/27 (66%) Frame = +3 Query: 594 NFNSKQLERLLQXATVKPVVNQVECHP 674 NF L LLQ AT+KP VNQ+E HP Sbjct: 146 NFMEHHLTPLLQHATIKPTVNQIEYHP 172 >UniRef50_Q9FJK0 Cluster: Aldose reductase-like protein; n=3; core eudicotyledons|Rep: Aldose reductase-like protein - Arabidopsis thaliana (Mouse-ear cress) Length = 316 Score = 112 bits (270), Expect = 1e-23 Identities = 63/152 (41%), Positives = 87/152 (57%), Gaps = 2/152 (1%) Frame = +1 Query: 142 GESIPVFGLGTW-KSKPGEVT-QAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIKEGV 315 GE+IP+ G+GT+ K E T AV AI IGYRH D A +YG+E+ +G A+ I G Sbjct: 11 GETIPLLGMGTYCPQKDRESTISAVHQAIKIGYRHFDTAKIYGSEEALGTALGQAISYGT 70 Query: 316 VTREDLFITSKLWNTFHRPDLVXGXLQETLDNLNVQYLDLYLIHWPQAYKEDGSLFPTXQ 495 V R+DLF+TSKLW++ H + L +TL + + YLD YL+HWP K G P + Sbjct: 71 VQRDDLFVTSKLWSSDHHDPI--SALIQTLKTMGLDYLDNYLVHWPIKLK-PGVSEPIPK 127 Query: 496 SGKIQFSDXDYVDXWKAMEPLXKEGLVXSIGV 591 + + D + W+ ME + GL SIGV Sbjct: 128 EDEFE-KDLGIEETWQGMERCLEMGLCRSIGV 158 Score = 39.9 bits (89), Expect = 0.089 Identities = 19/34 (55%), Positives = 24/34 (70%) Frame = +3 Query: 594 NFNSKQLERLLQXATVKPVVNQVECHPLPHQKXL 695 NF+SK++ LL A+V P VNQVE HPL Q+ L Sbjct: 160 NFSSKKIFDLLDFASVSPSVNQVEMHPLWRQRKL 193 >UniRef50_Q7PM68 Cluster: ENSANGP00000014386; n=1; Anopheles gambiae str. PEST|Rep: ENSANGP00000014386 - Anopheles gambiae str. PEST Length = 310 Score = 112 bits (270), Expect = 1e-23 Identities = 65/166 (39%), Positives = 92/166 (55%), Gaps = 4/166 (2%) Frame = +1 Query: 106 MAPKIPV-VTFNNGESIPVFGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVG 282 M PK + ++ + ++P GLGT+ + +A++ AID+GYR D A YGNE VG Sbjct: 1 MIPKTCINLSDQHSIALPTIGLGTYSILGADGKEAIRTAIDVGYRMFDTAVAYGNEAIVG 60 Query: 283 EAITSKIKE-GVVTREDLFITSKLWNTFHRPDLVXGXLQETLDNLNVQYLDLYLIHWPQA 459 EAI KI+E +TR+D FI SKL ++HR DLV + TLD L + Y+DLYL+H P A Sbjct: 61 EAIREKIRECNNLTRDDFFIISKLSGSYHRQDLVEKCCRMTLDRLGMDYVDLYLMHTPVA 120 Query: 460 YKEDGSLFPTXQSGKIQFSDXDY--VDXWKAMEPLXKEGLVXSIGV 591 + + K+ D + W +E +EGL SIGV Sbjct: 121 LQSEKKC--ARNGTKLNAIDDSIAPTEAWIGLEQCYQEGLCRSIGV 164 Score = 34.3 bits (75), Expect = 4.4 Identities = 13/25 (52%), Positives = 17/25 (68%) Frame = +3 Query: 594 NFNSKQLERLLQXATVKPVVNQVEC 668 NFN Q+ LL A++ P VNQ+EC Sbjct: 166 NFNEHQINALLSDASIVPAVNQIEC 190 >UniRef50_Q88SL1 Cluster: Oxidoreductase; n=51; Lactobacillales|Rep: Oxidoreductase - Lactobacillus plantarum Length = 286 Score = 111 bits (268), Expect = 2e-23 Identities = 54/109 (49%), Positives = 68/109 (62%), Gaps = 1/109 (0%) Frame = +1 Query: 130 TFNNGESIPVFGLGTWKSKPGEVT-QAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIK 306 T NNG IP+ G GTW++ G+V +V A+ GYRHID A YGNE+ VG+AI Sbjct: 12 TLNNGTKIPIVGFGTWQTPDGQVAYDSVLAALKAGYRHIDTAAAYGNEESVGKAIA---- 67 Query: 307 EGVVTREDLFITSKLWNTFHRPDLVXGXLQETLDNLNVQYLDLYLIHWP 453 + V REDLF+T+KLWN H D L +L L + Y+DLYLIHWP Sbjct: 68 DSGVAREDLFVTTKLWNADHGYDAAKKALDTSLAKLGLDYVDLYLIHWP 116 >UniRef50_P06632 Cluster: 2,5-diketo-D-gluconic acid reductase A; n=8; Actinomycetales|Rep: 2,5-diketo-D-gluconic acid reductase A - Corynebacterium sp. (strain ATCC 31090) Length = 278 Score = 111 bits (268), Expect = 2e-23 Identities = 61/158 (38%), Positives = 86/158 (54%) Frame = +1 Query: 118 IPVVTFNNGESIPVFGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITS 297 +P + N+G SIP G G +K P + +AV++A+++GYRHID A +YGNE+ VG AI + Sbjct: 3 VPSIVLNDGNSIPQLGYGVFKVPPADTQRAVEEALEVGYRHIDTAAIYGNEEGVGAAIAA 62 Query: 298 KIKEGVVTREDLFITSKLWNTFHRPDLVXGXLQETLDNLNVQYLDLYLIHWPQAYKEDGS 477 + R+DLFIT+KLWN H D + E+L L + +DLYL+HWP + Sbjct: 63 ----SGIARDDLFITTKLWNDRHDGDEPAAAIAESLAKLALDQVDLYLVHWPTPAAD--- 115 Query: 478 LFPTXQSGKIQFSDXDYVDXWKAMEPLXKEGLVXSIGV 591 +YV W+ M L GL SIGV Sbjct: 116 ---------------NYVHAWEKMIELRAAGLTRSIGV 138 >UniRef50_Q5HR31 Cluster: Oxidoreductase, aldo/keto reductase family; n=3; Staphylococcus|Rep: Oxidoreductase, aldo/keto reductase family - Staphylococcus epidermidis (strain ATCC 35984 / RP62A) Length = 279 Score = 111 bits (266), Expect = 3e-23 Identities = 62/156 (39%), Positives = 86/156 (55%) Frame = +1 Query: 124 VVTFNNGESIPVFGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKI 303 V NNG +P GLG +K ++ + V+ A+D GYR D AY YGNEK +G A+ Sbjct: 5 VQILNNGYPMPAVGLGVYKIADEQMEEVVRTALDAGYRAFDTAYFYGNEKALGSAL---- 60 Query: 304 KEGVVTREDLFITSKLWNTFHRPDLVXGXLQETLDNLNVQYLDLYLIHWPQAYKEDGSLF 483 K V R++LFITSKLWN + D ++LDNL + YLDL+LIHWP Sbjct: 61 KHSNVERDELFITSKLWNDYQGYDQTIEYFNKSLDNLGLDYLDLFLIHWPCE-------- 112 Query: 484 PTXQSGKIQFSDXDYVDXWKAMEPLXKEGLVXSIGV 591 +D Y++ +KA+E L +EG + +IGV Sbjct: 113 ----------NDQLYIESYKALEHLYEEGKIKAIGV 138 >UniRef50_Q8J0K1 Cluster: 4-dihydromethyltrisporate dehydrogenase; n=2; Parasitella parasitica|Rep: 4-dihydromethyltrisporate dehydrogenase - Parasitella parasitica Length = 321 Score = 110 bits (265), Expect = 4e-23 Identities = 60/155 (38%), Positives = 80/155 (51%), Gaps = 6/155 (3%) Frame = +1 Query: 145 ESIPVFGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIKEGVVTR 324 + +P+ G G WK + + + AI IGYR D A YGNE EVG I IKEG+V R Sbjct: 13 DKMPLRGFGCWKIEKKDAENTIYQAIKIGYRLFDGACDYGNEVEVGRGINKAIKEGLVKR 72 Query: 325 EDLFITSKLWNTFHRPDLVXGXLQETLDNLNVQYLDLYLIHW--PQAYKEDGSLFP---- 486 E+LFI +KLWNTFH V L + ++Y DLYLIH+ P Y + +P Sbjct: 73 EELFIVTKLWNTFHSKQHVRTAFDRQLKDWGLEYFDLYLIHFPIPLQYVDPAVSYPPEWY 132 Query: 487 TXQSGKIQFSDXDYVDXWKAMEPLXKEGLVXSIGV 591 + K+ F + W ME L + L +IGV Sbjct: 133 VPHADKLNFERSPIHECWAEMEKLVQAKLTRNIGV 167 Score = 35.5 bits (78), Expect = 1.9 Identities = 18/42 (42%), Positives = 24/42 (57%) Frame = +3 Query: 594 NFNSKQLERLLQXATVKPVVNQVECHPLPHQKXLXSSVRLAG 719 NFN + + LL A +KP V Q+E HPL Q+ L V+ G Sbjct: 169 NFNCQAILDLLSYAKIKPAVLQIEIHPLLPQERLVKWVQEQG 210 >UniRef50_P38115 Cluster: D-arabinose dehydrogenase [NAD(P)+] heavy chain; n=3; Saccharomycetaceae|Rep: D-arabinose dehydrogenase [NAD(P)+] heavy chain - Saccharomyces cerevisiae (Baker's yeast) Length = 344 Score = 110 bits (265), Expect = 4e-23 Identities = 72/179 (40%), Positives = 99/179 (55%), Gaps = 15/179 (8%) Frame = +1 Query: 67 LRSSQAAAKLI--NKMAPKIPVVTF--NNGESIPVFGLGTWK--SKPGEVTQAVKDAIDI 228 + SS A+ + I N + PK + F NNG IP GLGT K E QAVK AI Sbjct: 1 MSSSVASTENIVENMLHPKTTEIYFSLNNGVRIPALGLGTANPHEKLAETKQAVKAAIKA 60 Query: 229 GYRHIDCAYVYGNEKEVGEAITSKIKEGVVTREDLFITSKLWNTFHRPDLVXGXLQETLD 408 GYRHID A+ Y E VGEAI +++G + REDLFIT+K+W D V L E+L Sbjct: 61 GYRHIDTAWAYETEPFVGEAIKELLEDGSIKREDLFITTKVWPVLW--DEVDRSLNESLK 118 Query: 409 NLNVQYLDLYLIHWPQAYKE-------DGSL-FPTXQSGKIQF-SDXDYVDXWKAMEPL 558 L ++Y+DL L HWP +++ G + P SGK + +D DY++ +K +E + Sbjct: 119 ALGLEYVDLLLQHWPLCFEKIKDPKGISGLVKTPVDDSGKTMYAADGDYLETYKQLEKI 177 Score = 38.3 bits (85), Expect = 0.27 Identities = 18/33 (54%), Positives = 23/33 (69%), Gaps = 1/33 (3%) Frame = +3 Query: 594 NFNSKQLERLLQXATVKPVVNQVECHP-LPHQK 689 NF+ + LERL++ VKP VNQVE HP LP + Sbjct: 193 NFSIEYLERLIKECRVKPTVNQVETHPHLPQME 225 >UniRef50_UPI0000519CC2 Cluster: PREDICTED: similar to CG2767-PA; n=1; Apis mellifera|Rep: PREDICTED: similar to CG2767-PA - Apis mellifera Length = 321 Score = 110 bits (264), Expect = 6e-23 Identities = 56/153 (36%), Positives = 91/153 (59%), Gaps = 2/153 (1%) Frame = +1 Query: 139 NGESIPVFGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIKEGVV 318 NGE +P+ G GTW+++ E+ A+ A++ GYRHID A Y NEK +G+ + + + Sbjct: 10 NGELMPIIGFGTWQAQEKELEDALNIALEAGYRHIDTATSYENEKVIGDVLKNWFDSKKL 69 Query: 319 TREDLFITSKLWNTFHRPDLVXGXLQETLDNLNVQYLDLYLIHWPQAYKEDGS-LFPTXQ 495 R D+FI +KL +R + V ++ +L NL ++YLDLYLIH P +++ G L P + Sbjct: 70 KRSDIFIVTKLPAVGNRAEDVEKWIKTSLQNLRLEYLDLYLIHVPIGFEKVGDILHPFDE 129 Query: 496 SGKIQF-SDXDYVDXWKAMEPLXKEGLVXSIGV 591 +G I+ + ++V+ W ME K G +IG+ Sbjct: 130 NGHIRLDNSTNHVEIWAEMEKQVKCGRTKAIGL 162 >UniRef50_Q7N0E4 Cluster: 2,5-diketo-D-gluconic acid reductase A; n=2; Bacteria|Rep: 2,5-diketo-D-gluconic acid reductase A - Photorhabdus luminescens subsp. laumondii Length = 292 Score = 110 bits (264), Expect = 6e-23 Identities = 62/157 (39%), Positives = 87/157 (55%) Frame = +1 Query: 121 PVVTFNNGESIPVFGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSK 300 P++ +G +P GLG+W S ++ + + A+DIGYR ID A +Y NEK VG A Sbjct: 5 PIIRLADGNHMPQLGLGSWASDDQQIAETIHAALDIGYRAIDTAAIYNNEKGVGNA---- 60 Query: 301 IKEGVVTREDLFITSKLWNTFHRPDLVXGXLQETLDNLNVQYLDLYLIHWPQAYKEDGSL 480 ++E + RED+F+T+KLWN H L E+L+ L + Y+DLYLIHWP A +D Sbjct: 61 LQETDIPREDIFVTTKLWNDRHLD--ARAALTESLEKLQLDYVDLYLIHWP-APPQD--- 114 Query: 481 FPTXQSGKIQFSDXDYVDXWKAMEPLXKEGLVXSIGV 591 YV W+ + L KEGL+ SIGV Sbjct: 115 --------------QYVGAWQQLIELQKEGLIRSIGV 137 Score = 38.3 bits (85), Expect = 0.27 Identities = 15/34 (44%), Positives = 22/34 (64%) Frame = +3 Query: 594 NFNSKQLERLLQXATVKPVVNQVECHPLPHQKXL 695 NF + ++RL+ V PV+NQ+E HPL Q+ L Sbjct: 139 NFQPEHIQRLINETGVHPVINQIELHPLLQQRQL 172 >UniRef50_Q4Q5N9 Cluster: Prostaglandin f synthase, putative; n=7; cellular organisms|Rep: Prostaglandin f synthase, putative - Leishmania major Length = 279 Score = 109 bits (262), Expect = 1e-22 Identities = 51/116 (43%), Positives = 72/116 (62%) Frame = +1 Query: 106 MAPKIPVVTFNNGESIPVFGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGE 285 MA K VT +NG +P G+GTW++K G +K A++ GYRH+D A+ Y NEK VG+ Sbjct: 1 MAVKCTHVTLSNGVQVPQLGIGTWEAKDGNEVVNIKWAVNAGYRHVDTAHYYKNEKGVGQ 60 Query: 286 AITSKIKEGVVTREDLFITSKLWNTFHRPDLVXGXLQETLDNLNVQYLDLYLIHWP 453 I+ E V R D+F+T+KLWN H + +++ L V+Y+DLYLIHWP Sbjct: 61 GIS----ECGVPRSDIFVTTKLWNYDHGYESALAAFEQSRQALGVEYVDLYLIHWP 112 Score = 36.3 bits (80), Expect = 1.1 Identities = 18/34 (52%), Positives = 20/34 (58%) Frame = +3 Query: 594 NFNSKQLERLLQXATVKPVVNQVECHPLPHQKXL 695 NF L+ LL TV P+VNQVE HP QK L Sbjct: 141 NFEPHHLDDLLANCTVPPMVNQVEMHPHFQQKAL 174 >UniRef50_Q9ZBW7 Cluster: Putative oxidoreductase; n=2; Actinomycetales|Rep: Putative oxidoreductase - Streptomyces coelicolor Length = 277 Score = 109 bits (261), Expect = 1e-22 Identities = 62/162 (38%), Positives = 84/162 (51%) Frame = +1 Query: 106 MAPKIPVVTFNNGESIPVFGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGE 285 M+ K+P + NNG +P G G W+ + AV A++ GYR ID A +YGNE+ G Sbjct: 1 MSSKVPPIILNNGVEMPQLGFGVWQVPDDDAQTAVALALEAGYRSIDTAAIYGNEEGTGR 60 Query: 286 AITSKIKEGVVTREDLFITSKLWNTFHRPDLVXGXLQETLDNLNVQYLDLYLIHWPQAYK 465 AI + + REDLF+T+KLWN+ D ++ L ++YLDLYLIHWP K Sbjct: 61 AIAA----SGLAREDLFVTTKLWNSDQGYDSTLRAFDTSMAKLGLEYLDLYLIHWPMPAK 116 Query: 466 EDGSLFPTXQSGKIQFSDXDYVDXWKAMEPLXKEGLVXSIGV 591 E YVD +KA E L +G V +IGV Sbjct: 117 E------------------RYVDTYKAFEKLLADGRVRAIGV 140 >UniRef50_Q83N50 Cluster: 2,5-diketo-D-gluconic acid reductase; n=2; Tropheryma whipplei|Rep: 2,5-diketo-D-gluconic acid reductase - Tropheryma whipplei (strain Twist) (Whipple's bacillus) Length = 283 Score = 108 bits (260), Expect = 2e-22 Identities = 53/112 (47%), Positives = 74/112 (66%) Frame = +1 Query: 118 IPVVTFNNGESIPVFGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITS 297 +P V +G SIP FGLGT++ P E + V+ AI++GYRHID A +Y NE+EVG AI S Sbjct: 9 VPSVLLGDGVSIPQFGLGTYELPPNEASSVVQSAIELGYRHIDTASLYANEREVGRAIAS 68 Query: 298 KIKEGVVTREDLFITSKLWNTFHRPDLVXGXLQETLDNLNVQYLDLYLIHWP 453 + RE+ F+T+KLWN+ +P + +LD L++ Y+DLYLIHWP Sbjct: 69 ----SGIKREEFFVTTKLWNS-DQPK-PREAFERSLDLLSLDYVDLYLIHWP 114 >UniRef50_Q4JX70 Cluster: Putative oxidoreductase; n=1; Corynebacterium jeikeium K411|Rep: Putative oxidoreductase - Corynebacterium jeikeium (strain K411) Length = 285 Score = 108 bits (260), Expect = 2e-22 Identities = 51/121 (42%), Positives = 73/121 (60%), Gaps = 2/121 (1%) Frame = +1 Query: 97 INKMAPKIPVVTFNNGESIPVFGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKE 276 +N+ +P + N+G++ P GLG W+ + +V+ AI+ GYRHID A +YGNE+ Sbjct: 1 MNEKNNAVPTLEMNDGKTTPQLGLGVWQLSDEDTYTSVRAAIETGYRHIDTAAIYGNEEA 60 Query: 277 VGEAITSKIKEGVVTREDLFITSKLWNTFHRPDLVXG--XLQETLDNLNVQYLDLYLIHW 450 VG A+ +K G V RE+LFIT+KLWN D G E+ L + Y+DLYL+HW Sbjct: 61 VGRAVADAVKAGDVQREELFITTKLWNA----DQACGKEAFAESQKKLGMDYVDLYLLHW 116 Query: 451 P 453 P Sbjct: 117 P 117 >UniRef50_A7BA05 Cluster: Putative uncharacterized protein; n=1; Actinomyces odontolyticus ATCC 17982|Rep: Putative uncharacterized protein - Actinomyces odontolyticus ATCC 17982 Length = 292 Score = 108 bits (259), Expect = 2e-22 Identities = 50/112 (44%), Positives = 69/112 (61%) Frame = +1 Query: 118 IPVVTFNNGESIPVFGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITS 297 IP G IPV G GT+K P + AV A+++GYRHID A +YGNE EVG A Sbjct: 16 IPTFMLPTGSPIPVLGFGTYKVAPEDTYDAVSRALEVGYRHIDTAQMYGNEAEVGAA--- 72 Query: 298 KIKEGVVTREDLFITSKLWNTFHRPDLVXGXLQETLDNLNVQYLDLYLIHWP 453 ++ + REDLFIT+K+ N+ H PD ++ +L++L Y+DL L+HWP Sbjct: 73 -LEASGIAREDLFITTKVDNSNHEPDRAAASIRRSLEDLRTDYVDLLLVHWP 123 >UniRef50_Q9X0A2 Cluster: Oxidoreductase, aldo/keto reductase family; n=21; Bacteria|Rep: Oxidoreductase, aldo/keto reductase family - Thermotoga maritima Length = 286 Score = 107 bits (257), Expect = 4e-22 Identities = 62/159 (38%), Positives = 88/159 (55%) Frame = +1 Query: 115 KIPVVTFNNGESIPVFGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAIT 294 ++P VT NNG +P+ G G ++ P + + V +AI +GYR ID A Y NE+ VG AI Sbjct: 2 QVPKVTLNNGVEMPILGYGVFQIPPEKTEECVYEAIKVGYRLIDTAASYMNEEGVGRAIK 61 Query: 295 SKIKEGVVTREDLFITSKLWNTFHRPDLVXGXLQETLDNLNVQYLDLYLIHWPQAYKEDG 474 I EG+V RE+LF+T+KLW + + +++L L ++Y+DLYLIH P Sbjct: 62 RAIDEGIVRREELFVTTKLWVSDVGYESTKKAFEKSLKKLQLEYIDLYLIHQP------- 114 Query: 475 SLFPTXQSGKIQFSDXDYVDXWKAMEPLXKEGLVXSIGV 591 F D WKAME + K+GLV +IGV Sbjct: 115 ------------FGDVHCA--WKAMEEMYKDGLVRAIGV 139 >UniRef50_A6WDZ5 Cluster: Aldo/keto reductase; n=5; Bacteria|Rep: Aldo/keto reductase - Kineococcus radiotolerans SRS30216 Length = 343 Score = 107 bits (256), Expect = 5e-22 Identities = 57/161 (35%), Positives = 83/161 (51%), Gaps = 4/161 (2%) Frame = +1 Query: 118 IPVVTFNNGESIPVFGLGTWKS---KPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEA 288 +P G ++P G+GT+ S P EV AV A+ GYR +DCA VYGNE +VGEA Sbjct: 13 VPRRELRGGATVPAIGIGTFGSDRYSPAEVAAAVAGAVAAGYRLVDCAAVYGNEAQVGEA 72 Query: 289 ITSKIKEGVVTREDLFITSKLWNTFHRPDLVXGXLQETLDNLNVQYLDLYLIHWPQAYKE 468 + + G V R++LF+ SK+WN H P + +L +L + +LD +HWP Sbjct: 73 LAGAVAGG-VDRDELFVVSKVWNDAHAPADAVASVHRSLRDLRLDHLDAVFVHWPFPNHH 131 Query: 469 DGSLFPTXQSGKIQFSDXD-YVDXWKAMEPLXKEGLVXSIG 588 + + + D D Y+ W A+E L GLV +G Sbjct: 132 PPMADTDARDPRARPYDHDAYLALWGALEGLVDSGLVRHLG 172 >UniRef50_A3LTU8 Cluster: D-arabinose dehydrogenase; n=5; Saccharomycetales|Rep: D-arabinose dehydrogenase - Pichia stipitis (Yeast) Length = 326 Score = 106 bits (255), Expect = 7e-22 Identities = 61/162 (37%), Positives = 93/162 (57%), Gaps = 10/162 (6%) Frame = +1 Query: 136 NNGESIPVFGLGTWKSK-PGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIKEG 312 +NG++IP GLGT + P E+ + V A+ GYRHID A+ YG E+ +G+A+ +EG Sbjct: 13 SNGKTIPALGLGTVPPEDPHELKEQVITAVKAGYRHIDTAWYYGTEEYIGQALKQLFEEG 72 Query: 313 VVTREDLFITSKLWNTFHRPDLVXGXLQETLDNLNVQYLDLYLIHWPQAYKEDGSLF--- 483 +V REDLFIT+K+W +F R L ++L +L + Y+DL+L HWP D + Sbjct: 73 IVKREDLFITTKVWPSFWRNP--EKSLDKSLADLGLDYVDLFLQHWPVVLHGDENGLPPQ 130 Query: 484 PTXQSGKIQFSD-----XDYVDXWKAMEP-LXKEGLVXSIGV 591 P + GK+ + D Y+D + ++E + V SIGV Sbjct: 131 PRDKDGKLIYDDDPVSGIKYIDAYHSLEDIMDNTSKVKSIGV 172 >UniRef50_Q05KR9 Cluster: Benzil reductase; n=5; Bacillales|Rep: Benzil reductase - Bacillus subtilis Length = 276 Score = 106 bits (254), Expect = 9e-22 Identities = 66/156 (42%), Positives = 87/156 (55%), Gaps = 1/156 (0%) Frame = +1 Query: 127 VTFNNGESIPVFGLGTWKSKPG-EVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKI 303 V +NG +P FGLG +K + G E T++VK AI GYR ID A +Y NE+ VG I Sbjct: 9 VKLHNGVEMPWFGLGVFKVENGNEATESVKAAIKNGYRSIDTAAIYKNEEGVGIGI---- 64 Query: 304 KEGVVTREDLFITSKLWNTFHRPDLVXGXLQETLDNLNVQYLDLYLIHWPQAYKEDGSLF 483 KE V RE+LFITSK+WN + +++L+ L + YLDLYLIHWP Sbjct: 65 KESGVAREELFITSKVWNEDQGYETTLAAFEKSLERLQLDYLDLYLIHWP---------- 114 Query: 484 PTXQSGKIQFSDXDYVDXWKAMEPLXKEGLVXSIGV 591 GK Y D W+A+E L K+G + +IGV Sbjct: 115 -----GK-----DKYKDTWRALEKLYKDGKIRAIGV 140 Score = 40.3 bits (90), Expect = 0.068 Identities = 20/42 (47%), Positives = 24/42 (57%) Frame = +3 Query: 594 NFNSKQLERLLQXATVKPVVNQVECHPLPHQKXLXSSVRLAG 719 NF LE LL+ A +KP+VNQVE HP QK L + G Sbjct: 142 NFQVHHLEELLKDAEIKPMVNQVEFHPRLTQKELRDYCKAQG 183 >UniRef50_A2QL02 Cluster: Putative frameshift; n=1; Aspergillus niger|Rep: Putative frameshift - Aspergillus niger Length = 357 Score = 106 bits (254), Expect = 9e-22 Identities = 59/155 (38%), Positives = 87/155 (56%), Gaps = 1/155 (0%) Frame = +1 Query: 130 TFNNGESIPVFGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIKE 309 T N G IP G+GT++ P + V + G R ID A VYG E++VG I K+ Sbjct: 39 TLNTGAKIPALGVGTFQD-PDSQEETVCQVLQRGMRLIDTARVYGVEQQVGRGI----KK 93 Query: 310 GVVTREDLFITSKLW-NTFHRPDLVXGXLQETLDNLNVQYLDLYLIHWPQAYKEDGSLFP 486 V RE++F+ +KLW N FH PD V + ++L +L Y+DL L+H+P +K FP Sbjct: 94 SGVPREEIFLGTKLWCNDFH-PDDVERAVDDSLRDLYTPYVDLLLMHYPCTFKRGEDRFP 152 Query: 487 TXQSGKIQFSDXDYVDXWKAMEPLXKEGLVXSIGV 591 G++ + +VD W+A+E + K G V +IGV Sbjct: 153 RDAEGRMIHGETTFVDTWRALEKVVKTGKVRAIGV 187 >UniRef50_UPI00006CD296 Cluster: oxidoreductase, aldo/keto reductase family protein; n=1; Tetrahymena thermophila SB210|Rep: oxidoreductase, aldo/keto reductase family protein - Tetrahymena thermophila SB210 Length = 295 Score = 105 bits (252), Expect = 2e-21 Identities = 57/152 (37%), Positives = 89/152 (58%), Gaps = 1/152 (0%) Frame = +1 Query: 139 NGESIPVFGLGTWKS-KPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIKEGV 315 NG +PVFGLGT+K E+ ++ A+D+GYRHID A +Y NEK++G+A+ KEG Sbjct: 12 NGSKLPVFGLGTYKVVSKEEMVTFLRTALDLGYRHIDTAIMYENEKQIGDALQEIYKEGK 71 Query: 316 VTREDLFITSKLWNTFHRPDLVXGXLQETLDNLNVQYLDLYLIHWPQAYKEDGSLFPTXQ 495 REDLF+ +KL++ ++ V ++++L NL Y+DLYL+H+ S PT Q Sbjct: 72 YKREDLFLVTKLFS--NKNTKVEDQVRQSLQNLQTNYIDLYLLHY-------ASSPPTDQ 122 Query: 496 SGKIQFSDXDYVDXWKAMEPLXKEGLVXSIGV 591 + + W E L ++GL+ +IG+ Sbjct: 123 ---FELTHKPVFQVWAEFEELVQKGLIRNIGI 151 >UniRef50_Q968S3 Cluster: Aldoketoreductase-like protein; n=1; Orconectes limosus|Rep: Aldoketoreductase-like protein - Orconectes limosus (Spinycheek crayfish) Length = 336 Score = 105 bits (252), Expect = 2e-21 Identities = 62/165 (37%), Positives = 86/165 (52%), Gaps = 6/165 (3%) Frame = +1 Query: 115 KIPVVTFNNGESIPVFGLGTW------KSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKE 276 KIP + N+G IPV GLGT K VT ++ A++ GYRH D A YGNE Sbjct: 10 KIPTILLNSGSHIPVMGLGTGSLGRNGKMSEEAVTAVLETALECGYRHFDSAAYYGNEAI 69 Query: 277 VGEAITSKIKEGVVTREDLFITSKLWNTFHRPDLVXGXLQETLDNLNVQYLDLYLIHWPQ 456 +G+ + I EG V RE+LFIT+KL +R V LQ++LDNL + Y+DLYL+H+P Sbjct: 70 IGQVLRRWISEGKVKREELFITTKLPTRGNREKDVARFLQKSLDNLRLPYVDLYLVHYPC 129 Query: 457 AYKEDGSLFPTXQSGKIQFSDXDYVDXWKAMEPLXKEGLVXSIGV 591 + + + D W+AME G +IG+ Sbjct: 130 GILDTDRERLSADEVTVD-PTTDIHAIWRAMEAQLAAGKTKNIGL 173 >UniRef50_Q7R2T6 Cluster: GLP_291_56367_57278; n=1; Giardia lamblia ATCC 50803|Rep: GLP_291_56367_57278 - Giardia lamblia ATCC 50803 Length = 303 Score = 105 bits (251), Expect = 2e-21 Identities = 57/150 (38%), Positives = 78/150 (52%), Gaps = 4/150 (2%) Frame = +1 Query: 154 PVFGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIKEGV--VTRE 327 P G GT+ + E A++ A+ +GYRH DCAY YGNE+ +GE + V RE Sbjct: 6 PCVGFGTYLVEDPE---AIRSAVKLGYRHFDCAYRYGNERMIGEVFKEIFNDDSYGVKRE 62 Query: 328 DLFITSKLWNTFHRPDLVXGXLQETLDNLNVQYLDLYLIHWPQAYKE--DGSLFPTXQSG 501 DL+I SKLW FH P+ V + ETL +L ++YLD++L+HWP A K D + G Sbjct: 63 DLWIVSKLWPNFHEPEKVAYQISETLRDLQLEYLDVFLMHWPLAIKHLADRDYASSDGKG 122 Query: 502 KIQFSDXDYVDXWKAMEPLXKEGLVXSIGV 591 W+AME + IGV Sbjct: 123 GTLLGTTPIRKTWEAMEACVDKKQTRFIGV 152 >UniRef50_Q838E0 Cluster: Oxidoreductase, aldo/keto reductase family; n=24; Bacilli|Rep: Oxidoreductase, aldo/keto reductase family - Enterococcus faecalis (Streptococcus faecalis) Length = 279 Score = 104 bits (249), Expect = 4e-21 Identities = 54/131 (41%), Positives = 73/131 (55%), Gaps = 3/131 (2%) Frame = +1 Query: 127 VTFNNGESIPVFGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIK 306 VT NNG IP GLG ++ E + V++ I GYR ID A +YGNE G I + + Sbjct: 9 VTLNNGTKIPGMGLGVFQIPDEETAKVVEEGIINGYRLIDTAQIYGNESGTGAGIKAGLA 68 Query: 307 EGVVTREDLFITSKLWNTFHRPDLVXGXLQETLDNLNVQYLDLYLIHWP--QAYKEDGSL 480 + REDLF+TSK+WN D ++L+ L + YLDLYLIHWP +YKE Sbjct: 69 ATGLNREDLFVTSKVWNAHISYDETIQAFNDSLERLGLDYLDLYLIHWPGNNSYKESWQA 128 Query: 481 FPTXQS-GKIQ 510 T + GK++ Sbjct: 129 LETLYAEGKVK 139 Score = 36.3 bits (80), Expect = 1.1 Identities = 18/32 (56%), Positives = 19/32 (59%) Frame = +3 Query: 594 NFNSKQLERLLQXATVKPVVNQVECHPLPHQK 689 NF LE LL A V PV+NQVE HP QK Sbjct: 145 NFQVHHLEDLLSYAKVVPVINQVELHPKLDQK 176 >UniRef50_Q41E86 Cluster: 2,5-didehydrogluconate reductase; n=2; Bacteria|Rep: 2,5-didehydrogluconate reductase - Exiguobacterium sibiricum 255-15 Length = 274 Score = 103 bits (248), Expect = 5e-21 Identities = 59/155 (38%), Positives = 84/155 (54%) Frame = +1 Query: 127 VTFNNGESIPVFGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIK 306 VT NNG +P G G +K EV +AV++A+ +GYR ID A +Y NE VG A +K Sbjct: 4 VTLNNGLVMPQLGYGVFKVPEQEVYEAVREALRVGYRSIDTAMIYENEAGVGRA----LK 59 Query: 307 EGVVTREDLFITSKLWNTFHRPDLVXGXLQETLDNLNVQYLDLYLIHWPQAYKEDGSLFP 486 + + RED+F+T+K+WN + + +L L V Y+DLYLIHWP D L Sbjct: 60 DSGIPREDIFLTTKVWNKDQGYERTLAAFETSLQKLGVDYVDLYLIHWPM---PDEDL-- 114 Query: 487 TXQSGKIQFSDXDYVDXWKAMEPLXKEGLVXSIGV 591 Y+D W+A+E L ++G +IGV Sbjct: 115 -------------YMDTWRALEQLYRDGKAKAIGV 136 Score = 35.5 bits (78), Expect = 1.9 Identities = 15/34 (44%), Positives = 21/34 (61%) Frame = +3 Query: 594 NFNSKQLERLLQXATVKPVVNQVECHPLPHQKXL 695 NF+ L R+L+ TV P VNQ+E HP Q+ + Sbjct: 138 NFHIPHLTRVLEEGTVVPAVNQIELHPFLSQEAI 171 >UniRef50_Q03XK0 Cluster: Aldo/keto reductase of diketogulonate reductase family; n=3; Lactobacillales|Rep: Aldo/keto reductase of diketogulonate reductase family - Leuconostoc mesenteroides subsp. mesenteroides (strain ATCC 8293 /NCDO 523) Length = 292 Score = 103 bits (248), Expect = 5e-21 Identities = 52/109 (47%), Positives = 67/109 (61%), Gaps = 1/109 (0%) Frame = +1 Query: 130 TFNNGESIPVFGLGTWK-SKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIK 306 T +G +P+ G G ++ + G QAV DAI GYR ID A YGNE+EVGEAI I Sbjct: 5 TLASGIEMPLLGFGVFQVQEKGAAKQAVLDAIKTGYRLIDTAASYGNEREVGEAILEAIN 64 Query: 307 EGVVTREDLFITSKLWNTFHRPDLVXGXLQETLDNLNVQYLDLYLIHWP 453 +G+V RE+LF+TSK+W +Q +L LN+ YLDLYLIH P Sbjct: 65 QGIVKREELFVTSKMWVQDVSAQQATAAIQSSLQRLNLDYLDLYLIHQP 113 >UniRef50_Q4PDR0 Cluster: Putative uncharacterized protein; n=1; Ustilago maydis|Rep: Putative uncharacterized protein - Ustilago maydis (Smut fungus) Length = 339 Score = 103 bits (247), Expect = 6e-21 Identities = 63/176 (35%), Positives = 96/176 (54%), Gaps = 14/176 (7%) Frame = +1 Query: 106 MAPKIPVVTFNNGESIPVFGLGTWKSKPG-----EVTQAVKDAIDIGYRHIDCAYVYGNE 270 MA IP T N G +P G+G W+ +PG E+ A+ AI +GYRH+D A Y NE Sbjct: 1 MAANIPSFTLNTGAKLPSVGMGCWQGQPGPGRDNELVDALVRAIKVGYRHLDTATGYRNE 60 Query: 271 KEVGEAITSKIKEGVVTREDLFITSKLWNTFHRPDLVXGXLQE---TLDNLNVQYLDLYL 441 EVG+A+ ++ V R ++F+T+KL RP V +QE +L+ L + Y+DL+L Sbjct: 61 AEVGQAV----RQSGVARSEIFVTTKL-----RPGGVHDVVQELENSLNELGIDYIDLWL 111 Query: 442 IHWPQAYKEDGSLFPTXQSGKIQFS---DXDYVDXWKAMEPL---XKEGLVXSIGV 591 +HWPQ + +D F T +S ++ + + W ME + +G V +IGV Sbjct: 112 LHWPQGFTKDDGGFGTGESFGLEHQKHLGPTFNETWAKMEDVFLNSHKGKVKAIGV 167 Score = 33.9 bits (74), Expect = 5.9 Identities = 16/33 (48%), Positives = 21/33 (63%), Gaps = 1/33 (3%) Frame = +3 Query: 594 NFNSKQLERLLQXATVKPVVNQVECHP-LPHQK 689 NF+ K LE L + + V P VNQ+E HP LP + Sbjct: 169 NFSIKNLEILAKTSKVTPAVNQIEAHPYLPEHE 201 >UniRef50_Q8ET73 Cluster: 2,5-diketo-D-gluconate reductase; n=12; Bacteria|Rep: 2,5-diketo-D-gluconate reductase - Oceanobacillus iheyensis Length = 280 Score = 102 bits (244), Expect = 1e-20 Identities = 62/162 (38%), Positives = 84/162 (51%) Frame = +1 Query: 106 MAPKIPVVTFNNGESIPVFGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGE 285 M +IP VT ++G +IP G GT++ + QA+ +AID GYR ID AY Y NE VGE Sbjct: 1 MVNQIPNVTLHDGLTIPKVGFGTYRLNGNDGVQAINNAIDHGYRLIDTAYNYENEGTVGE 60 Query: 286 AITSKIKEGVVTREDLFITSKLWNTFHRPDLVXGXLQETLDNLNVQYLDLYLIHWPQAYK 465 A ++ RE L ITSKL +H D +QE+L N+ Y DLYLIHWP + Sbjct: 61 A----VRRSSTPREQLLITSKLPGRYHHYDKAVTTIQESLYRANLDYYDLYLIHWPNPIQ 116 Query: 466 EDGSLFPTXQSGKIQFSDXDYVDXWKAMEPLXKEGLVXSIGV 591 + YV+ W+A+ + G + SIGV Sbjct: 117 D------------------IYVEAWQALIEAKRRGYIRSIGV 140 >UniRef50_A6LZ55 Cluster: 2,5-didehydrogluconate reductase; n=1; Clostridium beijerinckii NCIMB 8052|Rep: 2,5-didehydrogluconate reductase - Clostridium beijerinckii NCIMB 8052 Length = 289 Score = 102 bits (244), Expect = 1e-20 Identities = 61/152 (40%), Positives = 83/152 (54%), Gaps = 1/152 (0%) Frame = +1 Query: 139 NGESIPVFGLGTWKSKPGEVTQ-AVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIKEGV 315 NG IP G G +K GE + AV +AI IGYRH D A +YGNEK++G AI ++ Sbjct: 12 NGIKIPQVGFGVYKLNKGEDFETAVGEAIKIGYRHFDTAKIYGNEKDLGLAI----EKSQ 67 Query: 316 VTREDLFITSKLWNTFHRPDLVXGXLQETLDNLNVQYLDLYLIHWPQAYKEDGSLFPTXQ 495 + RE+ FITSK+WNT H + ++T LNV+YLD+YLIH+ +Y Sbjct: 68 IPREEFFITSKVWNTDHGYEATKKAFEQTCKKLNVEYLDMYLIHFASSY----------- 116 Query: 496 SGKIQFSDXDYVDXWKAMEPLXKEGLVXSIGV 591 Y++ W AME L +G + IGV Sbjct: 117 ----------YLETWHAMEELYLQGKIKVIGV 138 >UniRef50_P82125 Cluster: 1,5-anhydro-D-fructose reductase; n=1; Sus scrofa|Rep: 1,5-anhydro-D-fructose reductase - Sus scrofa (Pig) Length = 206 Score = 102 bits (244), Expect = 1e-20 Identities = 62/127 (48%), Positives = 71/127 (55%), Gaps = 1/127 (0%) Frame = +1 Query: 151 IPVFGLGTWKSKPG-EVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIKEGVVTRE 327 IPV GLGTW++ PG EVT+AVK AID GYRH D AY+Y NE EVG I +KI EGVV RE Sbjct: 2 IPVLGLGTWQAAPGGEVTEAVKVAIDTGYRHPDSAYLYHNEDEVGVGIQAKIDEGVVRRE 61 Query: 328 DLFITSKLWNTFHRPDLVXGXLQETLDNLNVQYLDLYLIHWPQAYKEDGSLFPTXQSGKI 507 DLFI SK YLDL IHWP +K P +SG I Sbjct: 62 DLFIVSK----------------------KXXYLDLXNIHWPMQFKPGEVDLPVDRSGMI 99 Query: 508 QFSDXDY 528 S+ D+ Sbjct: 100 VASNTDF 106 >UniRef50_A2UAH0 Cluster: Aldo/keto reductase; n=1; Bacillus coagulans 36D1|Rep: Aldo/keto reductase - Bacillus coagulans 36D1 Length = 273 Score = 101 bits (243), Expect = 2e-20 Identities = 59/152 (38%), Positives = 82/152 (53%), Gaps = 1/152 (0%) Frame = +1 Query: 139 NGESIPVFGLGTWKSKPGEVT-QAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIKEGV 315 NG +IP GLGTW+ GE T AV A+ GYRHID AY Y NE+ VG+A+ ++ Sbjct: 12 NGVAIPKIGLGTWQVPNGETTYHAVSFALKNGYRHIDTAYAYHNEESVGKAV----RDSG 67 Query: 316 VTREDLFITSKLWNTFHRPDLVXGXLQETLDNLNVQYLDLYLIHWPQAYKEDGSLFPTXQ 495 + R D+F+TSKL D ET+ N ++ LDLYLIH P + E G+ + Sbjct: 68 IDRRDIFVTSKLPAEIKSYDKALKTFDETMGNFGLEQLDLYLIHAPWPWSEKGADY---- 123 Query: 496 SGKIQFSDXDYVDXWKAMEPLXKEGLVXSIGV 591 + ++ WKAME + + G +IGV Sbjct: 124 -------TKENIEVWKAMEEIYESGRCRAIGV 148 >UniRef50_A0JRJ3 Cluster: 2,5-didehydrogluconate reductase; n=3; Actinobacteria (class)|Rep: 2,5-didehydrogluconate reductase - Arthrobacter sp. (strain FB24) Length = 276 Score = 101 bits (243), Expect = 2e-20 Identities = 61/157 (38%), Positives = 79/157 (50%) Frame = +1 Query: 121 PVVTFNNGESIPVFGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSK 300 PV+ N+G IP GLGTW +V AV +A++ GYRHID A YGNEK VG I S Sbjct: 5 PVIELNDGHRIPQIGLGTWPLDDHQVAAAVVNAVEGGYRHIDTAVKYGNEKGVGNGIRS- 63 Query: 301 IKEGVVTREDLFITSKLWNTFHRPDLVXGXLQETLDNLNVQYLDLYLIHWPQAYKEDGSL 480 + R +LFIT+KL F D L +L L + Y+DL LIHWP ++ Sbjct: 64 ---SGLDRSELFITTKLDGEFQGQDRAVAGLDGSLKRLGLDYVDLLLIHWPLPRRD---- 116 Query: 481 FPTXQSGKIQFSDXDYVDXWKAMEPLXKEGLVXSIGV 591 +++ WK E L +G V SIGV Sbjct: 117 --------------EFISTWKTFERLQADGKVRSIGV 139 >UniRef50_A5AD50 Cluster: Putative uncharacterized protein; n=3; Magnoliophyta|Rep: Putative uncharacterized protein - Vitis vinifera (Grape) Length = 304 Score = 101 bits (243), Expect = 2e-20 Identities = 48/85 (56%), Positives = 57/85 (67%) Frame = +1 Query: 106 MAPKIPVVTFNNGESIPVFGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGE 285 M+ I N G +P GLGTW+S PG V QAV AI +GYRHIDCA VYGNE+E+G Sbjct: 1 MSDDIRFFQLNTGAKMPSVGLGTWQSDPGLVGQAVAIAIKVGYRHIDCAQVYGNEEEIGI 60 Query: 286 AITSKIKEGVVTREDLFITSKLWNT 360 + +GVV REDL+ITSKLW T Sbjct: 61 VLKKLFDDGVVKREDLWITSKLWCT 85 >UniRef50_Q8ZI40 Cluster: 2,5-diketo-D-gluconic acid reductase A; n=74; Bacteria|Rep: 2,5-diketo-D-gluconic acid reductase A - Yersinia pestis Length = 277 Score = 101 bits (243), Expect = 2e-20 Identities = 60/158 (37%), Positives = 86/158 (54%), Gaps = 1/158 (0%) Frame = +1 Query: 121 PVVTFNNGESIPVFGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSK 300 P++ +G +P GLG W++ E AV A+++GYR ID A +Y NE+ VG+A Sbjct: 5 PLIKLYDGRLMPQLGLGVWQASIQETELAVSKALEVGYRSIDTAAIYKNEEGVGKA---- 60 Query: 301 IKEGVVTREDLFITSKLWN-TFHRPDLVXGXLQETLDNLNVQYLDLYLIHWPQAYKEDGS 477 +K V R++LFIT+KLWN H P L+ +L L + Y+DLYLIHWP K+D Sbjct: 61 LKAAAVARDELFITTKLWNDDQHNPQQA---LETSLQKLQLDYVDLYLIHWPDP-KQD-- 114 Query: 478 LFPTXQSGKIQFSDXDYVDXWKAMEPLXKEGLVXSIGV 591 YV W+ + L ++GL+ SIGV Sbjct: 115 ---------------HYVSAWRELVTLKEQGLIRSIGV 137 Score = 36.7 bits (81), Expect = 0.83 Identities = 15/34 (44%), Positives = 21/34 (61%) Frame = +3 Query: 594 NFNSKQLERLLQXATVKPVVNQVECHPLPHQKXL 695 NF+ L+RL+ + P VNQ+E HPL Q+ L Sbjct: 139 NFHIPHLQRLIDETGIAPTVNQIELHPLLQQRQL 172 >UniRef50_A7CUW0 Cluster: 2,5-didehydrogluconate reductase; n=6; Bacteria|Rep: 2,5-didehydrogluconate reductase - Opitutaceae bacterium TAV2 Length = 334 Score = 101 bits (242), Expect = 3e-20 Identities = 64/182 (35%), Positives = 95/182 (52%), Gaps = 8/182 (4%) Frame = +1 Query: 70 RSSQAAAKLINKMAPK--------IPVVTFNNGESIPVFGLGTWKSKPGEVTQAVKDAID 225 R+S+ K+ K+ P+ IP + ++G SIP GLG W+ ++ A + Sbjct: 35 RNSEKGRKVWRKLQPRAWCYTMRMIPTLPLSDGTSIPQLGLGVWQMPDDGAGVPIQAAFN 94 Query: 226 IGYRHIDCAYVYGNEKEVGEAITSKIKEGVVTREDLFITSKLWNTFHRPDLVXGXLQETL 405 GYR ID A +YGNE+ VG AI + + R++L+IT+K+WN+ D ++E+L Sbjct: 95 AGYRAIDTAPIYGNEEGVGRAI----RASGLPRKELYITTKVWNSAQGYDSTLRAVRESL 150 Query: 406 DNLNVQYLDLYLIHWPQAYKEDGSLFPTXQSGKIQFSDXDYVDXWKAMEPLXKEGLVXSI 585 L ++Y+DLYLIHWP KI YVD WKA+ + +GL SI Sbjct: 151 GRLQLEYVDLYLIHWPVP--------------KID----RYVDTWKALAKIKADGLARSI 192 Query: 586 GV 591 GV Sbjct: 193 GV 194 >UniRef50_Q9ZUJ6 Cluster: T2K10.1 protein; n=16; core eudicotyledons|Rep: T2K10.1 protein - Arabidopsis thaliana (Mouse-ear cress) Length = 176 Score = 101 bits (242), Expect = 3e-20 Identities = 58/166 (34%), Positives = 86/166 (51%), Gaps = 8/166 (4%) Frame = +1 Query: 118 IPVVTFNNG----ESIPVFGLGTWKS---KPGEVTQAVKDAIDIGYRHIDCAYVYGNEKE 276 +P + +G S+PV G GT S +P + + V +AI +GYRH D + Y E+ Sbjct: 6 VPTLAIRSGPSGHHSMPVLGFGTAASPLPEPTMLKETVIEAIKLGYRHFDTSPRYQTEEP 65 Query: 277 VGEAITSKIKEGVV-TREDLFITSKLWNTFHRPDLVXGXLQETLDNLNVQYLDLYLIHWP 453 +GEA+ + G+V +R + F+T+KLW LV ++ +L NL + YLDLY+IHWP Sbjct: 66 IGEALAEAVSLGLVRSRSEFFVTTKLWCADAHGGLVVPAIKRSLKNLKLDYLDLYIIHWP 125 Query: 454 QAYKEDGSLFPTXQSGKIQFSDXDYVDXWKAMEPLXKEGLVXSIGV 591 + K FP + F D+ W ME + GL IGV Sbjct: 126 VSSKPGKYKFPIDED---DFMPMDFEVVWSEMEECQRLGLAKCIGV 168 >UniRef50_Q68ST9 Cluster: Reductase AKOR2; n=2; Pleurotus djamor|Rep: Reductase AKOR2 - Pleurotus djamor Length = 306 Score = 101 bits (241), Expect = 3e-20 Identities = 62/164 (37%), Positives = 87/164 (53%), Gaps = 7/164 (4%) Frame = +1 Query: 121 PVVTFNNGESIPVFGLGTWKSKPGEVTQAVKD----AIDIGYRHIDCAYVYGNEKEVGEA 288 P + N G +P LG W E K+ A+ GYRHID A +Y EK VG A Sbjct: 5 PPIVLNTGARMPALALGGWAGLTEEERTQAKEWFLTALKSGYRHIDTAQIYYTEKSVGNA 64 Query: 289 ITSKIKEGVVTREDLFITSKL-WNTFHRPDLVXGXLQETLDNLNVQYLDLYLIHWPQ-AY 462 I +E + RE+LFIT+KL WN R V Q++L+NL +Y+DLYL+H+PQ + Sbjct: 65 I----RESGIPREELFITTKLPWNHHSR---VAESFQKSLENLGTEYIDLYLVHFPQRVF 117 Query: 463 KEDGSLFPTXQSGKIQFSDXDYV-DXWKAMEPLXKEGLVXSIGV 591 ++ + FP G I+ + + D W +E L G V +IGV Sbjct: 118 YDETTDFPRNPDGSIKVVNSPTLNDVWADVETLLDTGKVKAIGV 161 Score = 37.5 bits (83), Expect = 0.48 Identities = 19/42 (45%), Positives = 24/42 (57%) Frame = +3 Query: 594 NFNSKQLERLLQXATVKPVVNQVECHPLPHQKXLXSSVRLAG 719 N++ K LE LL+ A V P VNQVE HP Q L + + G Sbjct: 163 NYSIKTLEELLKTAKVVPAVNQVELHPFLAQSKLLAYCKEKG 204 >UniRef50_Q03X85 Cluster: Aldo/keto reductase of diketogulonate reductase family; n=1; Leuconostoc mesenteroides subsp. mesenteroides ATCC 8293|Rep: Aldo/keto reductase of diketogulonate reductase family - Leuconostoc mesenteroides subsp. mesenteroides (strain ATCC 8293 /NCDO 523) Length = 288 Score = 99 bits (238), Expect = 8e-20 Identities = 51/129 (39%), Positives = 69/129 (53%), Gaps = 2/129 (1%) Frame = +1 Query: 130 TFNNGESIPVFGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIKE 309 T NNG +P G G ++ E QAV DAI+ GYR ID A VYGNE E G+ + I Sbjct: 5 TLNNGAQMPQLGFGVFQIPAEETKQAVVDAINAGYRSIDTARVYGNEAETGQGVNEAIAN 64 Query: 310 GVVTREDLFITSKLWNTFHRPDLVXGXLQETLDNLNVQYLDLYLIHWP--QAYKEDGSLF 483 VV RE+LF+T+KLW + + G + ++L L Y DL L+H P Y +L Sbjct: 65 AVVAREELFLTTKLWLSEFSYEAAKGAIDDSLKKLGTDYADLILLHQPYGDVYGAYKALA 124 Query: 484 PTXQSGKIQ 510 GK++ Sbjct: 125 EAQADGKVK 133 >UniRef50_A6NPD6 Cluster: Putative uncharacterized protein; n=3; Bacteria|Rep: Putative uncharacterized protein - Bacteroides capillosus ATCC 29799 Length = 287 Score = 99 bits (238), Expect = 8e-20 Identities = 60/154 (38%), Positives = 81/154 (52%), Gaps = 2/154 (1%) Frame = +1 Query: 136 NNGESIPVFGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIKEGV 315 +NG SIP G GT+K+ G+ + + +AI GYRH D A YG E +G+A+ E Sbjct: 11 SNGLSIPAVGFGTYKTGDGD-SAVLSNAIAQGYRHFDTASFYGTETALGQAVA----ESD 65 Query: 316 VTREDLFITSKLWNTFHRPDLVXGXLQETLDNLNVQYLDLYLIHWPQAYKEDGSLFPTXQ 495 + RED F+TSKLW T D TL+ L YLDLYLIHWP+ Sbjct: 66 IPREDFFLTSKLWKTEMGYDAALRAFDATLERLGTDYLDLYLIHWPRP------------ 113 Query: 496 SGKIQFSDXDYVD--XWKAMEPLXKEGLVXSIGV 591 ++ D +D W+A+E L + GLV +IGV Sbjct: 114 --DLELEDWAKLDRETWRALERLYESGLVRAIGV 145 >UniRef50_UPI00015B5BD7 Cluster: PREDICTED: similar to aldo-keto reductase; n=1; Nasonia vitripennis|Rep: PREDICTED: similar to aldo-keto reductase - Nasonia vitripennis Length = 310 Score = 99.5 bits (237), Expect = 1e-19 Identities = 60/164 (36%), Positives = 96/164 (58%), Gaps = 2/164 (1%) Frame = +1 Query: 106 MAPKIPVVTFNNGESIPVFGLGTWKSKPGEVTQAVKD-AIDIGYRHIDCAYVYGNEKEVG 282 + P I + NNG +P+ G+GT+K + EV + V D + +G+R ID A VY NE+++G Sbjct: 19 LTPTIRDLRLNNGYDMPLVGIGTYKVRGREVIKRVIDESFAVGFRSIDTAVVYRNEEDIG 78 Query: 283 EAITSKIKEGVVTREDLFITSKLWNTFH-RPDLVXGXLQETLDNLNVQYLDLYLIHWPQA 459 A+ + + + RED+FITSKL + + PD + ++++L L+ YLDLYLIHWP A Sbjct: 79 LALKELLPKYNLKREDIFITSKLSPSDNGDPDKIRKSVEDSLKALDTSYLDLYLIHWPGA 138 Query: 460 YKEDGSLFPTXQSGKIQFSDXDYVDXWKAMEPLXKEGLVXSIGV 591 + L + + K++ V W + L ++GL+ SIGV Sbjct: 139 SR---ILENSPDNPKLR------VTTWATLVELQQKGLLRSIGV 173 Score = 33.9 bits (74), Expect = 5.9 Identities = 16/28 (57%), Positives = 19/28 (67%), Gaps = 1/28 (3%) Frame = +3 Query: 594 NFNSKQLERLLQXAT-VKPVVNQVECHP 674 N+ LE LL+ + VKP VNQVECHP Sbjct: 175 NYTVGHLEHLLEHCSGVKPDVNQVECHP 202 >UniRef50_UPI00015B4912 Cluster: PREDICTED: similar to aldo-keto reductase; n=1; Nasonia vitripennis|Rep: PREDICTED: similar to aldo-keto reductase - Nasonia vitripennis Length = 353 Score = 99.1 bits (236), Expect = 1e-19 Identities = 56/159 (35%), Positives = 87/159 (54%), Gaps = 3/159 (1%) Frame = +1 Query: 124 VVTFNNGESIPVFGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKI 303 V ++G + P+ GLGT + + A++ G HID ++VY NE+ +G+ + Sbjct: 30 VYRLSSGHNFPIVGLGTHGLNEDVLETVLTGALEKGIGHIDTSFVYKNEETIGKVLKDWF 89 Query: 304 KEGVVTREDLFITSKLWNTFHRPDLVXGXLQETLDNLNVQYLDLYLIHWPQA--YKEDGS 477 +G RED+F+TSKL + P+ V ++ +L+ L +QYLD+YLIH P A +KED Sbjct: 90 AKGG-KREDIFVTSKLPYYDNHPESVEKYIKLSLEKLGLQYLDMYLIHAPFAVHHKEDSY 148 Query: 478 LFPTXQSGKIQF-SDXDYVDXWKAMEPLXKEGLVXSIGV 591 T + G + + D + WK ME KEG SIG+ Sbjct: 149 ELATNEDGSVVLDTQTDPIAVWKEMEKQVKEGRTKSIGL 187 >UniRef50_Q88TV9 Cluster: Oxidoreductase; n=4; Lactobacillus|Rep: Oxidoreductase - Lactobacillus plantarum Length = 288 Score = 99.1 bits (236), Expect = 1e-19 Identities = 50/114 (43%), Positives = 69/114 (60%), Gaps = 1/114 (0%) Frame = +1 Query: 115 KIPVVTFNNGESIPVFGLGTWK-SKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAI 291 K P +T N+G +IP G GT++ G QAVK+A+ IGYRHID A Y NE EVG+A Sbjct: 3 KTPTITLNDGRAIPAIGFGTFQIPDDGSTYQAVKEALVIGYRHIDTAVAYFNEDEVGQA- 61 Query: 292 TSKIKEGVVTREDLFITSKLWNTFHRPDLVXGXLQETLDNLNVQYLDLYLIHWP 453 IK+ + R+ +++TSKLW + D + +L L + Y+DLYLIH P Sbjct: 62 ---IKDSGIPRDQIWVTSKLWLQDYGFDAASRAIDRSLTKLRLDYIDLYLIHQP 112 >UniRef50_Q7VG53 Cluster: Aldo-keto reductase; n=28; Bacteria|Rep: Aldo-keto reductase - Helicobacter hepaticus Length = 292 Score = 99.1 bits (236), Expect = 1e-19 Identities = 62/155 (40%), Positives = 84/155 (54%), Gaps = 1/155 (0%) Frame = +1 Query: 130 TFNNGESIPVFGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAI-TSKIK 306 T NNG IP GLGTW+ V AV++A +GYRHID A YGNE+ VGEA+ SKIK Sbjct: 16 TLNNGNKIPKLGLGTWRIDDNVVEAAVREAFKVGYRHIDTAQAYGNERGVGEAVRKSKIK 75 Query: 307 EGVVTREDLFITSKLWNTFHRPDLVXGXLQETLDNLNVQYLDLYLIHWPQAYKEDGSLFP 486 RE+LFITSK+ + + +L + + ++DL LIH PQ + Sbjct: 76 -----REELFITSKIRAEYKDYKSASASIDTSLKTMKLDFIDLMLIHSPQPWN------- 123 Query: 487 TXQSGKIQFSDXDYVDXWKAMEPLXKEGLVXSIGV 591 + + G F + V+ + A+E K G V SIGV Sbjct: 124 SFRKGD-YFKEN--VEVYNALEDAQKAGKVRSIGV 155 >UniRef50_Q24C22 Cluster: Oxidoreductase, aldo/keto reductase family protein; n=4; Oligohymenophorea|Rep: Oxidoreductase, aldo/keto reductase family protein - Tetrahymena thermophila SB210 Length = 297 Score = 98.3 bits (234), Expect = 2e-19 Identities = 57/159 (35%), Positives = 83/159 (52%) Frame = +1 Query: 115 KIPVVTFNNGESIPVFGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAIT 294 K+P++ F G SIP G GT++ + + V +A+ IGY HID A VY NE+++ + I Sbjct: 12 KVPILNFREGGSIPQIGYGTYELRQNDCIIGVTEALKIGYTHIDTASVYRNEQDIAKVIH 71 Query: 295 SKIKEGVVTREDLFITSKLWNTFHRPDLVXGXLQETLDNLNVQYLDLYLIHWPQAYKEDG 474 + + REDLFITSK+ + +Q+ L LN++YLD LIHWP K Sbjct: 72 NPAYG--IKREDLFITSKISPGEQGYEQAKKAVQDMLTRLNIKYLDCVLIHWPGVSK--- 126 Query: 475 SLFPTXQSGKIQFSDXDYVDXWKAMEPLXKEGLVXSIGV 591 P Q ++ WKA+ L K G++ IGV Sbjct: 127 --LPPNDPKNAQIR----LETWKALIELRKAGVIKHIGV 159 Score = 33.5 bits (73), Expect = 7.8 Identities = 14/32 (43%), Positives = 19/32 (59%) Frame = +3 Query: 594 NFNSKQLERLLQXATVKPVVNQVECHPLPHQK 689 NFN L+ L++ + KP +NQ E HPL K Sbjct: 161 NFNINHLQHLIEKSEFKPEMNQFEIHPLCFNK 192 >UniRef50_Q4P4P1 Cluster: Putative uncharacterized protein; n=1; Ustilago maydis|Rep: Putative uncharacterized protein - Ustilago maydis (Smut fungus) Length = 322 Score = 98.3 bits (234), Expect = 2e-19 Identities = 49/110 (44%), Positives = 65/110 (59%), Gaps = 1/110 (0%) Frame = +1 Query: 127 VTFNNGESIPVFGLGTWKS-KPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKI 303 + NNG+ IP LG +K+ G A K A D GYRHID A Y NE+ VG A+ Sbjct: 19 IKLNNGQEIPQVALGVYKAPNDGSTENACKWAFDAGYRHIDSAARYMNEESVGRALAEWT 78 Query: 304 KEGVVTREDLFITSKLWNTFHRPDLVXGXLQETLDNLNVQYLDLYLIHWP 453 KE V R ++FITSKLW+ H D ++++L LNV Y+D+YL+H P Sbjct: 79 KENNVPRSEIFITSKLWDADH--DKAAAAIEDSLKKLNVDYMDMYLMHSP 126 Score = 35.1 bits (77), Expect = 2.5 Identities = 13/27 (48%), Positives = 19/27 (70%) Frame = +3 Query: 594 NFNSKQLERLLQXATVKPVVNQVECHP 674 NF+ ++L+ LL +KP VNQ+E HP Sbjct: 157 NFDVEELDHLLANCRIKPAVNQIESHP 183 >UniRef50_Q929C8 Cluster: Lin2349 protein; n=12; Listeria|Rep: Lin2349 protein - Listeria innocua Length = 294 Score = 96.7 bits (230), Expect = 7e-19 Identities = 64/150 (42%), Positives = 80/150 (53%), Gaps = 1/150 (0%) Frame = +1 Query: 145 ESIPVFGLGTWKSKPGE-VTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIKEGVVT 321 E+IP GLG ++ E + AV+ AI++GYR D A VY NE VG+AI + V Sbjct: 15 ETIPYIGLGVFQVTEQEFIAGAVEKAIEVGYRLFDTAAVYNNEAIVGQAIL----DSAVP 70 Query: 322 REDLFITSKLWNTFHRPDLVXGXLQETLDNLNVQYLDLYLIHWPQAYKEDGSLFPTXQSG 501 RE+LFI+SK+WN D + TL NL + YLDLYLIHWP A K Sbjct: 71 REELFISSKVWNGDLGYDETLFAFERTLRNLKLDYLDLYLIHWPVAGK------------ 118 Query: 502 KIQFSDXDYVDXWKAMEPLXKEGLVXSIGV 591 Y D W+AME L E L+ SIGV Sbjct: 119 --------YRDSWRAMERLHDEKLIKSIGV 140 Score = 35.5 bits (78), Expect = 1.9 Identities = 18/34 (52%), Positives = 19/34 (55%) Frame = +3 Query: 594 NFNSKQLERLLQXATVKPVVNQVECHPLPHQKXL 695 NF L LL A KPV+NQVE HPL Q L Sbjct: 142 NFKQHHLSDLLVAANEKPVLNQVETHPLLPQNDL 175 >UniRef50_A3C1Z7 Cluster: Putative uncharacterized protein; n=2; Oryza sativa (japonica cultivar-group)|Rep: Putative uncharacterized protein - Oryza sativa subsp. japonica (Rice) Length = 288 Score = 96.7 bits (230), Expect = 7e-19 Identities = 59/166 (35%), Positives = 88/166 (53%), Gaps = 8/166 (4%) Frame = +1 Query: 118 IPVVTFNNGESIPVFGLGTWK-----SKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVG 282 +P ++G+ +P G+GT + P V V AI+ GYRH D A VY E +G Sbjct: 1 MPEAALSSGKPMPRVGMGTASFPLGATDPSTVKDVVLRAIEAGYRHFDTAAVYQTEAILG 60 Query: 283 EAITSKIKEGVV-TREDLFITSKLWNTFHRPDLVXGXLQETLDNLNVQYLDLYLIHWPQA 459 +A+ ++ G+V +R++L+ITSKLW P V L+ L + ++YLDLYLIH+P + Sbjct: 61 DAVAEAVRAGLVASRDELYITSKLWVAHAHPGHVLPSLRRALRKMQMEYLDLYLIHFPVS 120 Query: 460 YK--EDGSLFPTXQSGKIQFSDXDYVDXWKAMEPLXKEGLVXSIGV 591 + ED T + D + V WK ME + GL +IGV Sbjct: 121 MRLAEDPESM-TYSKDDLVMMDMEGV--WKEMEECQRLGLTKAIGV 163 Score = 40.3 bits (90), Expect = 0.068 Identities = 18/34 (52%), Positives = 21/34 (61%) Frame = +3 Query: 594 NFNSKQLERLLQXATVKPVVNQVECHPLPHQKXL 695 NF+ K+LE LL AT+ P NQVE HP Q L Sbjct: 165 NFSCKKLETLLSFATISPAANQVEVHPYCRQNKL 198 >UniRef50_Q7G764 Cluster: Probable NAD(P)H-dependent oxidoreductase 1; n=32; Eukaryota|Rep: Probable NAD(P)H-dependent oxidoreductase 1 - Oryza sativa subsp. japonica (Rice) Length = 321 Score = 96.7 bits (230), Expect = 7e-19 Identities = 52/153 (33%), Positives = 83/153 (54%), Gaps = 4/153 (2%) Frame = +1 Query: 145 ESIPVFGLGTWK---SKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIKEGV 315 +++P G+GT + + T A+ AI++GYRH D A +Y E VGEA+ ++ G+ Sbjct: 14 QTMPRVGMGTAAFPFTSSEDTTAAMLRAIELGYRHFDTARIYATEGCVGEAVAEAVRRGL 73 Query: 316 V-TREDLFITSKLWNTFHRPDLVXGXLQETLDNLNVQYLDLYLIHWPQAYKEDGSLFPTX 492 + +R D+F+TSK+W + V +ETL NL + Y+DL L+HWP + FP Sbjct: 74 IASRADVFVTSKIWCSDLHAGRVVPAARETLRNLGMDYVDLLLVHWPVSLTPGNYDFPFP 133 Query: 493 QSGKIQFSDXDYVDXWKAMEPLXKEGLVXSIGV 591 + ++ D W+ ME + GL +IGV Sbjct: 134 K--EVILPSFDMEGVWRGMEECHRLGLARAIGV 164 Score = 43.2 bits (97), Expect = 0.010 Identities = 20/42 (47%), Positives = 28/42 (66%) Frame = +3 Query: 594 NFNSKQLERLLQXATVKPVVNQVECHPLPHQKXLXSSVRLAG 719 NF++K+LE+LL A V+P VNQVE +P+ Q+ L R G Sbjct: 166 NFSAKKLEQLLSLAAVRPAVNQVEVNPMWQQRTLREVCRREG 207 >UniRef50_Q7NB44 Cluster: ARA1; n=3; Firmicutes|Rep: ARA1 - Mycoplasma gallisepticum Length = 289 Score = 96.3 bits (229), Expect = 1e-18 Identities = 60/163 (36%), Positives = 90/163 (55%), Gaps = 4/163 (2%) Frame = +1 Query: 115 KIPVVTFN---NGESIPVFGLGTWKSKPGEVT-QAVKDAIDIGYRHIDCAYVYGNEKEVG 282 KI V+ +N N +P G GT+K + G+ T +AVK A+++GYRH+DCA +Y N+ V Sbjct: 7 KIKVMKYNLLANNYKMPSIGFGTYKLEDGKQTVEAVKTALEVGYRHLDCAEIYENQLSVS 66 Query: 283 EAITSKIKEGVVTREDLFITSKLWNTFHRPDLVXGXLQETLDNLNVQYLDLYLIHWPQAY 462 + I K V R+++FITSK+WN + + L +L+++YLDL LIHWP Sbjct: 67 QGI----KLSGVNRKEIFITSKIWNDDKGYESTKKAFHKILKDLDLEYLDLLLIHWPI-- 120 Query: 463 KEDGSLFPTXQSGKIQFSDXDYVDXWKAMEPLXKEGLVXSIGV 591 G F K + + + WKAME EG + +IG+ Sbjct: 121 ---GKGF------KDNWQEVN-AQTWKAMEEFYLEGKIKAIGL 153 >UniRef50_Q5FT75 Cluster: Putative 2,5-diketo-D-gluconic acid reductase; n=1; Gluconobacter oxydans|Rep: Putative 2,5-diketo-D-gluconic acid reductase - Gluconobacter oxydans (Gluconobacter suboxydans) Length = 279 Score = 96.3 bits (229), Expect = 1e-18 Identities = 55/156 (35%), Positives = 81/156 (51%) Frame = +1 Query: 124 VVTFNNGESIPVFGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKI 303 V++F++G ++P GLG W++ P E + VK+A+ +GYR +D A +Y NE+ VG Sbjct: 13 VISFHDGHTMPQIGLGVWETPPDETAEVVKEAVKLGYRSVDTARLYKNEEGVG------- 65 Query: 304 KEGVVTREDLFITSKLWNTFHRPDLVXGXLQETLDNLNVQYLDLYLIHWPQAYKEDGSLF 483 +G+ ++F+T+KLWN D +E+ L LDLYLIHWP Sbjct: 66 -KGLEDHPEIFLTTKLWNDEQGYDSTLRAYEESARLLRRPVLDLYLIHWPMP-------- 116 Query: 484 PTXQSGKIQFSDXDYVDXWKAMEPLXKEGLVXSIGV 591 + YV+ WKA+ L K G V SIGV Sbjct: 117 ----------AQGQYVETWKALVELKKSGRVKSIGV 142 Score = 37.9 bits (84), Expect = 0.36 Identities = 17/34 (50%), Positives = 22/34 (64%) Frame = +3 Query: 594 NFNSKQLERLLQXATVKPVVNQVECHPLPHQKXL 695 NF S+ LER++ V PVVNQ+E HP Q+ L Sbjct: 144 NFESEHLERIMDATGVVPVVNQIELHPDFQQRAL 177 >UniRef50_Q5TNP1 Cluster: ENSANGP00000029046; n=2; Culicidae|Rep: ENSANGP00000029046 - Anopheles gambiae str. PEST Length = 331 Score = 95.9 bits (228), Expect = 1e-18 Identities = 58/155 (37%), Positives = 84/155 (54%), Gaps = 3/155 (1%) Frame = +1 Query: 136 NNGESIPVFGLGTWKSKPGEVTQAVKD-AIDIGYRHIDCAYVYGNEKEVGEAITSKIKEG 312 N G IP+ G GT++ E+ V D A++ GYRHID A VY NE+ +G A+ + + + Sbjct: 37 NTGFDIPLAGFGTYQIHGQELIYQVLDYALEAGYRHIDTAVVYRNEEYIGTALKTLLPKY 96 Query: 313 VVTREDLFITSKLWNTFHRPD-LVXGXLQETLDNLNVQYLDLYLIHWPQAYKEDGSLFPT 489 + RED+FITSKL + + + V ++++L NL YLDLYLIHWP + G Sbjct: 97 NLKREDIFITSKLISQSGKDEAFVEQMVRKSLANLQTDYLDLYLIHWPGVSGKCGRWKWL 156 Query: 490 XQSGKIQFSDXDY-VDXWKAMEPLXKEGLVXSIGV 591 + Y W A+ L +EG + SIGV Sbjct: 157 FGMQVTHPDNVKYRAASWNALSKLEREGCLRSIGV 191 >UniRef50_Q4PHK0 Cluster: Putative uncharacterized protein; n=1; Ustilago maydis|Rep: Putative uncharacterized protein - Ustilago maydis (Smut fungus) Length = 355 Score = 95.9 bits (228), Expect = 1e-18 Identities = 67/190 (35%), Positives = 87/190 (45%), Gaps = 29/190 (15%) Frame = +1 Query: 109 APKIPVVTFNNGESIPVFGLGTWKSKPGEVTQAVKDAID-----------------IGYR 237 AP N G IPV GLGTW+S PGEV +AV+ AI +GY Sbjct: 8 APGQKTFKLNTGAEIPVIGLGTWQSAPGEVAKAVESAIKAGYRHIVSMLTSLLTLTLGYV 67 Query: 238 HI----------DCAYVYGNEKEVGEAITSKIKEGVVTREDLFITSKLWNTFHRPDLVXG 387 + D A++YGNE EVG+ I K V R +LF+T+K+W T+HR Sbjct: 68 ALHPLYIPFLAKDAAWIYGNENEVGQGI----KASGVPRSELFVTTKIWCTYHRQP--EA 121 Query: 388 XLQETLDNLNVQYLDLYLIHWP-QAYKEDGSLFPTXQSGKIQFS-DXDYVDXWKAMEPLX 561 L E+L L + Y+DL L+HWP K P + G D W+ ME L Sbjct: 122 CLDESLQRLGLDYVDLLLVHWPVPLVKRGDEKIPLNEDGSRAIDRDWSPEQTWELMEKLP 181 Query: 562 KEGLVXSIGV 591 G +IGV Sbjct: 182 ATGKTKAIGV 191 >UniRef50_Q1VRG6 Cluster: YvgN; n=1; Psychroflexus torquis ATCC 700755|Rep: YvgN - Psychroflexus torquis ATCC 700755 Length = 280 Score = 95.5 bits (227), Expect = 2e-18 Identities = 58/155 (37%), Positives = 86/155 (55%), Gaps = 3/155 (1%) Frame = +1 Query: 136 NNGESIPVFGLGTWKSKPGEVTQAV-KDAIDIGYRHIDCAYVYGNEKEVGEAITSKIKEG 312 N+G IP+ G GT+K+ E +++ K A+ +GYR ID +Y NE+ VG+AI ++ G Sbjct: 6 NDGNRIPIVGFGTYKANEEEGIKSIQKSALTLGYRLIDTVAIYQNEEAVGKAIKAR---G 62 Query: 313 VVTREDLFITSKLWNTFHRPDLVXGXLQETLDNLNVQYLDLYLIHWPQAYKEDGSLFPTX 492 V+ RE++F+T+KLW L E+L L++ Y+DLYLIHWP Sbjct: 63 VL-REEIFVTTKLWRENLGYKQTRIALDESLRKLDLNYIDLYLIHWP------------- 108 Query: 493 QSGKIQFSDXD--YVDXWKAMEPLXKEGLVXSIGV 591 + I + D D W+AME L EG + S+GV Sbjct: 109 -ANAINYKDWQKTNADTWRAMEELQAEGKIKSLGV 142 >UniRef50_A3UJS6 Cluster: Oxidoreductase; n=3; Alphaproteobacteria|Rep: Oxidoreductase - Oceanicaulis alexandrii HTCC2633 Length = 275 Score = 95.5 bits (227), Expect = 2e-18 Identities = 44/105 (41%), Positives = 61/105 (58%) Frame = +1 Query: 139 NGESIPVFGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIKEGVV 318 NG IP G GTW+ + + + V A+ GYRHID A +YGNE VG+ K+ V Sbjct: 8 NGADIPKLGFGTWQLEDEDAARGVATALKTGYRHIDTAQIYGNEAAVGDG----WKQSGV 63 Query: 319 TREDLFITSKLWNTFHRPDLVXGXLQETLDNLNVQYLDLYLIHWP 453 RED F+T+K+W R + ++E+LD L Y+DL L+HWP Sbjct: 64 KREDFFLTTKVWRDKFRDGDLQASVKESLDKLKTDYVDLLLLHWP 108 >UniRef50_O13848 Cluster: NADH/NADPH dependent indole-3-acetaldehyde reductase AKR3C2; n=1; Schizosaccharomyces pombe|Rep: NADH/NADPH dependent indole-3-acetaldehyde reductase AKR3C2 - Schizosaccharomyces pombe (Fission yeast) Length = 284 Score = 95.5 bits (227), Expect = 2e-18 Identities = 72/172 (41%), Positives = 91/172 (52%), Gaps = 6/172 (3%) Frame = +1 Query: 94 LINKMAPKIPVVTFNNGESIPVFGLGT--WKSKPGEVTQ----AVKDAIDIGYRHIDCAY 255 LI M PKIPV P +G+GT +K + GE+ + +VK+A+ G+ HIDCA Sbjct: 2 LIAAMGPKIPV---------PAYGVGTALFKKEKGEINRTIVDSVKNALAAGFIHIDCAE 52 Query: 256 VYGNEKEVGEAITSKIKEGVVTREDLFITSKLWNTFHRPDLVXGXLQETLDNLNVQYLDL 435 VYGNE+EVG A +KE V R LFITSK+ H D + L E+L L YLDL Sbjct: 53 VYGNEEEVGVA----LKEANVPRSKLFITSKV---MHNVDNIPEALNESLRKLGTDYLDL 105 Query: 436 YLIHWPQAYKEDGSLFPTXQSGKIQFSDXDYVDXWKAMEPLXKEGLVXSIGV 591 YL+H P + E KI S + WKAME GLV S+GV Sbjct: 106 YLLHSPIPFYEK----------KIPIS-----EGWKAMETALGTGLVHSVGV 142 Score = 34.3 bits (75), Expect = 4.4 Identities = 17/38 (44%), Positives = 22/38 (57%), Gaps = 2/38 (5%) Frame = +3 Query: 567 GSGXEHRS--PNFNSKQLERLLQXATVKPVVNQVECHP 674 G+G H NF LE LL+ +T+ P VNQ+E HP Sbjct: 133 GTGLVHSVGVSNFRIPDLEELLKTSTITPRVNQIEFHP 170 >UniRef50_Q7G765 Cluster: Probable NAD(P)H-dependent oxidoreductase 2; n=6; Magnoliophyta|Rep: Probable NAD(P)H-dependent oxidoreductase 2 - Oryza sativa subsp. japonica (Rice) Length = 322 Score = 95.1 bits (226), Expect = 2e-18 Identities = 55/152 (36%), Positives = 80/152 (52%), Gaps = 4/152 (2%) Frame = +1 Query: 148 SIPVFGLGTWK---SKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIKEGVV 318 ++P G+GT + E T A+ AI++GYRH D A +Y E V EA+ ++ G+V Sbjct: 17 TMPRIGMGTAAFPFTSSEETTAALLRAIELGYRHFDTARLYATEGCVSEAVAEAVRRGLV 76 Query: 319 -TREDLFITSKLWNTFHRPDLVXGXLQETLDNLNVQYLDLYLIHWPQAYKEDGSLFPTXQ 495 +R D+F+TSKLW + V +ETL NL + Y+DL L+HWP FP + Sbjct: 77 ASRADVFVTSKLWCSDLHAGRVVPAARETLRNLGMDYVDLLLVHWPATVAPGSYDFPFPK 136 Query: 496 SGKIQFSDXDYVDXWKAMEPLXKEGLVXSIGV 591 D + V W+ ME + GL +IGV Sbjct: 137 EEMAPAFDMEGV--WRGMEECHRLGLARAIGV 166 Score = 41.5 bits (93), Expect = 0.029 Identities = 19/42 (45%), Positives = 27/42 (64%) Frame = +3 Query: 594 NFNSKQLERLLQXATVKPVVNQVECHPLPHQKXLXSSVRLAG 719 NF++K+LE+LL A V+P NQVE +P+ Q+ L R G Sbjct: 168 NFSAKKLEQLLSFAVVRPAANQVEMNPMWQQRTLREVCRREG 209 >UniRef50_Q89JN4 Cluster: Oxidoreductase; n=8; Rhizobiales|Rep: Oxidoreductase - Bradyrhizobium japonicum Length = 272 Score = 93.9 bits (223), Expect = 5e-18 Identities = 42/108 (38%), Positives = 66/108 (61%) Frame = +1 Query: 139 NGESIPVFGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIKEGVV 318 NG IP GLGTW+ + V+ A+ +GYRHID A VY NE+EVG+ ++ V Sbjct: 7 NGARIPAIGLGTWELSGRPCARVVEQALRLGYRHIDTAQVYDNEREVGDG----VRASGV 62 Query: 319 TREDLFITSKLWNTFHRPDLVXGXLQETLDNLNVQYLDLYLIHWPQAY 462 R+D+F+T+K+W P+ + ++E+L L + +DL L+HWP ++ Sbjct: 63 RRDDVFLTTKVWTNHFAPNDLERSVKESLARLRLPSVDLLLLHWPNSH 110 >UniRef50_Q890A0 Cluster: Oxidoreductase; n=6; Lactobacillales|Rep: Oxidoreductase - Lactobacillus plantarum Length = 282 Score = 93.5 bits (222), Expect = 7e-18 Identities = 57/152 (37%), Positives = 80/152 (52%), Gaps = 1/152 (0%) Frame = +1 Query: 139 NGESIPVFGLGTWKSKPGEVT-QAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIKEGV 315 NG +IP GTW+ GE T QAV+ A+ GYRHID A Y NE VG+A I++ Sbjct: 12 NGVNIPKVAFGTWQIPGGEATYQAVRAALAAGYRHIDTALAYQNEASVGQA----IRDSG 67 Query: 316 VTREDLFITSKLWNTFHRPDLVXGXLQETLDNLNVQYLDLYLIHWPQAYKEDGSLFPTXQ 495 + RE +F+T+KL +L NL + Y+DLYL+H P +P Q Sbjct: 68 IPREQIFVTTKLPAETKSYQGALNDFDRSLKNLGLDYVDLYLVHAP---------WPWGQ 118 Query: 496 SGKIQFSDXDYVDXWKAMEPLXKEGLVXSIGV 591 G++ D +D W+AME + + G +IGV Sbjct: 119 VGRVY--DEANLDVWQAMEAIYQSGRAKAIGV 148 >UniRef50_Q5FLI5 Cluster: Aldehyde reductase; n=2; Bacteria|Rep: Aldehyde reductase - Lactobacillus acidophilus Length = 278 Score = 93.5 bits (222), Expect = 7e-18 Identities = 56/156 (35%), Positives = 81/156 (51%), Gaps = 1/156 (0%) Frame = +1 Query: 127 VTFNNGESIPVFGLGTWKSKP-GEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKI 303 VT NNG +P G G ++ + Q V+D +++GYR +D A +YGNE+ VG+AI Sbjct: 5 VTLNNGIKMPRLGFGVYQIDDLAQAQQVVEDGLEVGYRLVDTAQIYGNEQAVGDAI---- 60 Query: 304 KEGVVTREDLFITSKLWNTFHRPDLVXGXLQETLDNLNVQYLDLYLIHWPQAYKEDGSLF 483 K V RED+FITSK+W + D +++ L + Y+DLYLIH P Sbjct: 61 KHSNVPREDIFITSKIWVDDYGYDNTLKAFDDSMKKLQLDYIDLYLIHKPY--------- 111 Query: 484 PTXQSGKIQFSDXDYVDXWKAMEPLXKEGLVXSIGV 591 DY W+A+E L +EG + +IGV Sbjct: 112 ------------NDYYGTWRALERLYQEGRIRAIGV 135 >UniRef50_A0JRJ6 Cluster: Aldo/keto reductase; n=2; Micrococcineae|Rep: Aldo/keto reductase - Arthrobacter sp. (strain FB24) Length = 281 Score = 93.5 bits (222), Expect = 7e-18 Identities = 60/158 (37%), Positives = 79/158 (50%) Frame = +1 Query: 118 IPVVTFNNGESIPVFGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITS 297 IP +T NNG IP G G ++ P E + V+DA++ GYRHID A Y NE VG AI++ Sbjct: 9 IPQLTLNNGVKIPQLGFGVFQVPPEETQRIVEDALEAGYRHIDTAAAYRNEAGVGAAISA 68 Query: 298 KIKEGVVTREDLFITSKLWNTFHRPDLVXGXLQETLDNLNVQYLDLYLIHWPQAYKEDGS 477 + RED+FIT+KL N Q + L V+++DLYLIHWP Sbjct: 69 ----SGIPREDIFITTKLRN--GEQGNAHEAFQNSRKALGVEFVDLYLIHWPVP------ 116 Query: 478 LFPTXQSGKIQFSDXDYVDXWKAMEPLXKEGLVXSIGV 591 S Y + WKAME L + +IGV Sbjct: 117 ------------SQGLYTEAWKAMEKLYANSQIRAIGV 142 Score = 36.7 bits (81), Expect = 0.83 Identities = 19/42 (45%), Positives = 23/42 (54%) Frame = +3 Query: 594 NFNSKQLERLLQXATVKPVVNQVECHPLPHQKXLXSSVRLAG 719 NF + L+ LL A V P VNQVE HP Q+ L + R G Sbjct: 144 NFLGEHLDTLLPAADVVPAVNQVEIHPTFQQQELAAKCRELG 185 >UniRef50_Q3E9M9 Cluster: Uncharacterized protein At5g01670.2; n=7; Magnoliophyta|Rep: Uncharacterized protein At5g01670.2 - Arabidopsis thaliana (Mouse-ear cress) Length = 349 Score = 93.5 bits (222), Expect = 7e-18 Identities = 66/178 (37%), Positives = 88/178 (49%), Gaps = 27/178 (15%) Frame = +1 Query: 139 NGESIPVFGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIKEGVV 318 +G IP GLGTW+S V ++ GYRHID A+ YG+++EVG+ I + G+ Sbjct: 20 SGHKIPAVGLGTWRSGSQAAHAVVTAIVEGGYRHIDTAWEYGDQREVGQGIKRAMHAGL- 78 Query: 319 TREDLFIT----------------SKLWN-----------TFHRPDLVXGXLQETLDNLN 417 R DLF+T S L N T P+ V LQ TL L Sbjct: 79 ERRDLFVTSKLWYTLILRKMINLSSPLMNVLVGTCLNKRCTELSPERVRPALQNTLKELQ 138 Query: 418 VQYLDLYLIHWPQAYKEDGSLFPTXQSGKIQFSDXDYVDXWKAMEPLXKEGLVXSIGV 591 ++YLDLYLIHWP +E S P ++G + D D W+ ME L K+ LV +IGV Sbjct: 139 LEYLDLYLIHWPIRLREGASKPP--KAGDV--LDFDMEGVWREMENLSKDSLVRNIGV 192 >UniRef50_Q02198 Cluster: Morphine 6-dehydrogenase; n=5; Bacteria|Rep: Morphine 6-dehydrogenase - Pseudomonas putida Length = 296 Score = 93.5 bits (222), Expect = 7e-18 Identities = 46/116 (39%), Positives = 65/116 (56%) Frame = +1 Query: 106 MAPKIPVVTFNNGESIPVFGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGE 285 MA K P++ NNG +P GLG + + E A+ AI GYR ID A Y NE +VGE Sbjct: 1 MAGKSPLINLNNGVKMPALGLGVFAASAEETASAIASAISSGYRLIDTARSYNNEAQVGE 60 Query: 286 AITSKIKEGVVTREDLFITSKLWNTFHRPDLVXGXLQETLDNLNVQYLDLYLIHWP 453 I+ V R ++F+T+KL+N + + E+L L + Y+DLYL+HWP Sbjct: 61 G----IRNSGVDRAEMFVTTKLFNCDYGYERALRAFDESLGRLGLDYVDLYLLHWP 112 Score = 36.7 bits (81), Expect = 0.83 Identities = 18/42 (42%), Positives = 23/42 (54%) Frame = +3 Query: 594 NFNSKQLERLLQXATVKPVVNQVECHPLPHQKXLXSSVRLAG 719 NF QL+ L+ + V P VNQ+E HP QK L + R G Sbjct: 142 NFLEDQLDELIAASDVVPAVNQIELHPYFAQKPLLAKNRALG 183 >UniRef50_Q7WSY4 Cluster: Putative aldo-keto reductase; n=1; Propionibacterium freudenreichii subsp. shermanii|Rep: Putative aldo-keto reductase - Propionibacterium freudenreichii subsp. shermanii Length = 280 Score = 93.1 bits (221), Expect = 9e-18 Identities = 53/157 (33%), Positives = 81/157 (51%) Frame = +1 Query: 121 PVVTFNNGESIPVFGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSK 300 P V + G +P+ G+GTW K E AV AI+ GYR +D A YGNE+ VG+A Sbjct: 9 PTVELSGGTRMPMLGMGTWPLKGEECRAAVASAIEQGYRLVDTAEAYGNEEAVGKA---- 64 Query: 301 IKEGVVTREDLFITSKLWNTFHRPDLVXGXLQETLDNLNVQYLDLYLIHWPQAYKEDGSL 480 ++E R ++F+T+K +H V L+ +L+ L + Y+DL+L+HWP Sbjct: 65 VREAGPDRAEIFVTTKFSKQWHSRKGVHEALEHSLERLGLDYVDLFLMHWPMP------- 117 Query: 481 FPTXQSGKIQFSDXDYVDXWKAMEPLXKEGLVXSIGV 591 + YVD ++ M L ++GL +IGV Sbjct: 118 -----------GEGSYVDAYRGMVELKEQGLAKAIGV 143 >UniRef50_A4FEB9 Cluster: 2,5-diketo-D-gluconic acid reductase; n=1; Saccharopolyspora erythraea NRRL 2338|Rep: 2,5-diketo-D-gluconic acid reductase - Saccharopolyspora erythraea (strain NRRL 23338) Length = 159 Score = 93.1 bits (221), Expect = 9e-18 Identities = 46/112 (41%), Positives = 62/112 (55%) Frame = +1 Query: 118 IPVVTFNNGESIPVFGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITS 297 +P VT NNG +P G G ++ E AV A++ GYR ID A YGNE VG A+ Sbjct: 4 VPTVTLNNGVEMPQLGYGVFQVPEDETAAAVGAALEAGYRSIDTAAAYGNEAAVGRALAG 63 Query: 298 KIKEGVVTREDLFITSKLWNTFHRPDLVXGXLQETLDNLNVQYLDLYLIHWP 453 + R++LF+T+KLWN D +L+ L + +LDLYLIHWP Sbjct: 64 ----SGLARDELFVTTKLWNADQGYDNALRAFDTSLELLGLDHLDLYLIHWP 111 >UniRef50_A7P424 Cluster: Chromosome chr1 scaffold_5, whole genome shotgun sequence; n=1; Vitis vinifera|Rep: Chromosome chr1 scaffold_5, whole genome shotgun sequence - Vitis vinifera (Grape) Length = 247 Score = 93.1 bits (221), Expect = 9e-18 Identities = 67/172 (38%), Positives = 90/172 (52%), Gaps = 14/172 (8%) Frame = +1 Query: 118 IPVVTFNN-GESIPVFGLGT--WKSKPGE-VTQAVKDAIDIGYRHIDCAYVYGNEKEVGE 285 IP +T + G++IP+ G+ T + P E + ++ AI++GYRH DC Y +EK +GE Sbjct: 4 IPEMTLGSTGKAIPLVGMVTTVYPFAPSETMIDSILTAIELGYRHFDCVAAYLSEKPLGE 63 Query: 286 AITSKIKEGVV-TREDLFITSKLWNTFHRPDLVXGXLQETL---------DNLNVQYLDL 435 AI +K G++ +R++LFITSKLW + D V LQ TL NL + YLDL Sbjct: 64 AIKKAVKLGLIKSRDELFITSKLWCSDAHHDRVLPALQNTLKISSILSFSKNLQLDYLDL 123 Query: 436 YLIHWPQAYKEDGSLFPTXQSGKIQFSDXDYVDXWKAMEPLXKEGLVXSIGV 591 YLIHW DG L D WKAME K L +IGV Sbjct: 124 YLIHW-----SDGHL------------PIDLGSVWKAMEDFQKLSLTKAIGV 158 >UniRef50_Q5B034 Cluster: Putative uncharacterized protein; n=1; Emericella nidulans|Rep: Putative uncharacterized protein - Emericella nidulans (Aspergillus nidulans) Length = 186 Score = 93.1 bits (221), Expect = 9e-18 Identities = 64/153 (41%), Positives = 79/153 (51%), Gaps = 1/153 (0%) Frame = +1 Query: 136 NNGESIPVFGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIKEGV 315 N G IP GLGTWKS+PGEV +A+ A+ GYRHID A +G Sbjct: 10 NPGALIPAVGLGTWKSEPGEVARALAHALKTGYRHIDAA--------LG----------- 50 Query: 316 VTREDLFITSKLWNTFHRPDLVXGXLQETLDNLNVQYLDLYLIHWPQAYKEDGSLFPTXQ 495 V RE++FITSKLWNT H+P++ G LQ+TLD L V LDL Y E L P Sbjct: 51 VPREEIFITSKLWNT-HQPNIKEG-LQKTLDALGVDCLDL--------YNETSDLLPVNP 100 Query: 496 SG-KIQFSDXDYVDXWKAMEPLXKEGLVXSIGV 591 G + D + W+ ME K G +IGV Sbjct: 101 DGTRAVDRSWDQSETWRQMEDFYKSGKAKAIGV 133 >UniRef50_Q5FKI1 Cluster: Reductase-dehydrogenase; n=1; Lactobacillus acidophilus|Rep: Reductase-dehydrogenase - Lactobacillus acidophilus Length = 271 Score = 92.7 bits (220), Expect = 1e-17 Identities = 57/155 (36%), Positives = 76/155 (49%) Frame = +1 Query: 127 VTFNNGESIPVFGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIK 306 V NNGE IP LGTW EV + V+ A++IGYR D A YGNE VG+ I + Sbjct: 7 VILNNGEKIPQIQLGTWLINNDEVNKVVRQAVNIGYRGFDTAKDYGNESGVGKGIWN--- 63 Query: 307 EGVVTREDLFITSKLWNTFHRPDLVXGXLQETLDNLNVQYLDLYLIHWPQAYKEDGSLFP 486 + R D+F+T+KL + + LD ++Y+DL LIH PQ + E Sbjct: 64 -SDIERSDIFLTTKLPTAVKDYEGTKKAIDAALDKFGLEYIDLLLIHSPQPWIEVNRTND 122 Query: 487 TXQSGKIQFSDXDYVDXWKAMEPLXKEGLVXSIGV 591 G + + W+AME K G V SIGV Sbjct: 123 RHFKGNL--------ENWRAMEEAVKAGKVRSIGV 149 >UniRef50_Q1RFP0 Cluster: 2,5-diketo-D-gluconic acid reductase A; n=21; Bacteria|Rep: 2,5-diketo-D-gluconic acid reductase A - Escherichia coli (strain UTI89 / UPEC) Length = 294 Score = 92.3 bits (219), Expect = 2e-17 Identities = 58/154 (37%), Positives = 82/154 (53%), Gaps = 2/154 (1%) Frame = +1 Query: 136 NNGESIPVFGLGTWKSKPGEVT-QAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIKEG 312 +N +P+ G G ++ +V Q+V +AI GYR ID A VYGNE VGEA+ I EG Sbjct: 12 SNNLKMPMMGFGVFQVTDKDVCKQSVLNAIRTGYRLIDTAAVYGNEDAVGEAVREAISEG 71 Query: 313 VVTREDLFITSKLW-NTFHRPDLVXGXLQETLDNLNVQYLDLYLIHWPQAYKEDGSLFPT 489 + TRE+LFITSKLW D+ ++ +L ++Y DLYL+H QA + Sbjct: 72 LCTREELFITSKLWVQDMLNQDIAAAGIEASLKKSGLEYFDLYLLH--QAMR-------- 121 Query: 490 XQSGKIQFSDXDYVDXWKAMEPLXKEGLVXSIGV 591 DY W+A+E +EG + +IGV Sbjct: 122 -----------DYFSAWRALEDAYEEGKLKAIGV 144 >UniRef50_A0JX62 Cluster: 2,5-didehydrogluconate reductase; n=9; Bacteria|Rep: 2,5-didehydrogluconate reductase - Arthrobacter sp. (strain FB24) Length = 291 Score = 92.3 bits (219), Expect = 2e-17 Identities = 60/170 (35%), Positives = 85/170 (50%), Gaps = 13/170 (7%) Frame = +1 Query: 121 PVVTFNNGESIPVFGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAIT-- 294 P ++ NNG I G G +K P + V A++ GYRH D A +YGNE VG+AI Sbjct: 5 PRLSLNNGVLIDQLGFGLYKVPPADAAGLVTMALEAGYRHFDTAAMYGNETGVGKAIGAL 64 Query: 295 -----------SKIKEGVVTREDLFITSKLWNTFHRPDLVXGXLQETLDNLNVQYLDLYL 441 S ++REDLF+T+K+WN H D ++ NL ++Y+DLYL Sbjct: 65 AGFAGGGPAGGSGEAAPSLSREDLFVTTKVWNDDHGYDATMRAFDTSMSNLGMEYVDLYL 124 Query: 442 IHWPQAYKEDGSLFPTXQSGKIQFSDXDYVDXWKAMEPLXKEGLVXSIGV 591 IHWP A + LF + ++AME L +EG + +IGV Sbjct: 125 IHWPCARR---GLF---------------TESYRAMETLYREGRIRAIGV 156 Score = 35.9 bits (79), Expect = 1.5 Identities = 17/34 (50%), Positives = 19/34 (55%) Frame = +3 Query: 594 NFNSKQLERLLQXATVKPVVNQVECHPLPHQKXL 695 NF LE LL+ A V P VNQ+E HP Q L Sbjct: 158 NFQPAHLEHLLETAEVVPAVNQIELHPWLQQDEL 191 >UniRef50_UPI00006CCCD7 Cluster: oxidoreductase, aldo/keto reductase family protein; n=1; Tetrahymena thermophila SB210|Rep: oxidoreductase, aldo/keto reductase family protein - Tetrahymena thermophila SB210 Length = 323 Score = 91.9 bits (218), Expect = 2e-17 Identities = 60/175 (34%), Positives = 90/175 (51%), Gaps = 8/175 (4%) Frame = +1 Query: 91 KLINKMAPKIPVVTFNNGESIPVFGLGTW------KSKPGEVTQAVKDAIDIGYRHIDCA 252 K+IN+ I V NNG +P+ GLGT + E+T + +A+D GYR+ D A Sbjct: 6 KIINQ---DIKYVQLNNGYKMPLLGLGTQPYDIVTRVTVEEMTTLLSNALDFGYRNFDTA 62 Query: 253 YVYGNEKEVGEAITSKIKEGVVTREDLFITSKLWNTFHRPDLVXGXLQETLDNLNVQYLD 432 Y NE E+G+A + ++G RED+FIT+KL+ F + +Q +LD L Y+D Sbjct: 63 KQYRNEVEIGQAFQNIFQQGKYKREDVFITTKLF-PFKIEKKIKEVVQNSLDQLQTSYID 121 Query: 433 LYLIHWPQAYKEDGSLFP--TXQSGKIQFSDXDYVDXWKAMEPLXKEGLVXSIGV 591 LYLI W S P T G + + + W+ +E + G++ SIGV Sbjct: 122 LYLIQW--------SFTPVLTNFDGSVAVNHRPIHEVWRELEECVELGMIRSIGV 168 >UniRef50_Q28P63 Cluster: Aldo/keto reductase; n=4; Rhodobacteraceae|Rep: Aldo/keto reductase - Jannaschia sp. (strain CCS1) Length = 276 Score = 91.9 bits (218), Expect = 2e-17 Identities = 52/156 (33%), Positives = 80/156 (51%) Frame = +1 Query: 121 PVVTFNNGESIPVFGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSK 300 PV+ F++G IP G G W+ + V+ AI+IGYR ID AY+Y NE +GE Sbjct: 5 PVIKFHDGAQIPQVGFGIWQVPQDIAGETVRSAIEIGYRMIDGAYLYMNEAGLGEG---- 60 Query: 301 IKEGVVTREDLFITSKLWNTFHRPDLVXGXLQETLDNLNVQYLDLYLIHWPQAYKEDGSL 480 ++ + R+++F+T+K+WN ++ +L + V+ LDL LIHWP Sbjct: 61 LRASGLPRDEVFVTTKVWNNEQGAAKARASVERSLKTIGVEQLDLVLIHWPVP------- 113 Query: 481 FPTXQSGKIQFSDXDYVDXWKAMEPLXKEGLVXSIG 588 S Y++ WKA + + EGL+ SIG Sbjct: 114 -----------SQDLYLETWKAFQDMRDEGLMRSIG 138 >UniRef50_A5PDA8 Cluster: Putative oxidoreductase protein; n=1; Erythrobacter sp. SD-21|Rep: Putative oxidoreductase protein - Erythrobacter sp. SD-21 Length = 272 Score = 91.5 bits (217), Expect = 3e-17 Identities = 55/157 (35%), Positives = 77/157 (49%) Frame = +1 Query: 121 PVVTFNNGESIPVFGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSK 300 P + N+G IP G GTW+ + + QAV AID+GY ID A +YGNEK VG Sbjct: 5 PTLNLNDGRQIPQLGFGTWQMEEEDAPQAVSTAIDVGYWLIDTAAIYGNEKGVG------ 58 Query: 301 IKEGVVTREDLFITSKLWNTFHRPDLVXGXLQETLDNLNVQYLDLYLIHWPQAYKEDGSL 480 +GV D+F+ +K+WN D ++ L+ L +++D+ LIHWP K+ Sbjct: 59 --KGVGEWSDIFLQTKIWNDSQGYDRTLRAAEKCLERLGREHVDMLLIHWPCPEKD---- 112 Query: 481 FPTXQSGKIQFSDXDYVDXWKAMEPLXKEGLVXSIGV 591 +VD WKA+ L G SIGV Sbjct: 113 --------------QFVDTWKALIELRDAGKAKSIGV 135 >UniRef50_Q4V008 Cluster: Oxidoreductase; n=4; Proteobacteria|Rep: Oxidoreductase - Xanthomonas campestris pv. campestris (strain 8004) Length = 267 Score = 91.1 bits (216), Expect = 4e-17 Identities = 44/102 (43%), Positives = 64/102 (62%) Frame = +1 Query: 148 SIPVFGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIKEGVVTRE 327 ++P FGLGT++ K V +V++A+ +GYR ID A +Y NE +VG+AI + V R+ Sbjct: 2 TVPAFGLGTFRLKDQVVIDSVRNALALGYRAIDTAQIYDNEAQVGQAIA----DAGVPRD 57 Query: 328 DLFITSKLWNTFHRPDLVXGXLQETLDNLNVQYLDLYLIHWP 453 LF+T+K+W D + LQE+L L Y+DL LIHWP Sbjct: 58 QLFVTTKIWVDRFSRDTLQPSLQESLRKLGTDYVDLTLIHWP 99 >UniRef50_Q15NA5 Cluster: Aldo/keto reductase; n=2; Gammaproteobacteria|Rep: Aldo/keto reductase - Pseudoalteromonas atlantica (strain T6c / BAA-1087) Length = 273 Score = 91.1 bits (216), Expect = 4e-17 Identities = 43/102 (42%), Positives = 64/102 (62%) Frame = +1 Query: 148 SIPVFGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIKEGVVTRE 327 +IP G GT++ K + AV++A+D+GYRHID A Y NE EVG+AI++ ++R Sbjct: 10 TIPTPGFGTYRLKGDDAKLAVENALDVGYRHIDTAQAYENEAEVGDAISA----SKISRG 65 Query: 328 DLFITSKLWNTFHRPDLVXGXLQETLDNLNVQYLDLYLIHWP 453 +LF+T+K+W D +Q +L LN Y+DL L+HWP Sbjct: 66 ELFVTTKVWFDNLSADKFITSVQNSLTQLNTDYVDLLLVHWP 107 >UniRef50_Q14LU6 Cluster: Putative aldo/keto reductase oxidoreductase protein; n=1; Spiroplasma citri|Rep: Putative aldo/keto reductase oxidoreductase protein - Spiroplasma citri Length = 138 Score = 91.1 bits (216), Expect = 4e-17 Identities = 46/103 (44%), Positives = 65/103 (63%), Gaps = 1/103 (0%) Frame = +1 Query: 139 NGESIPVFGLGTWK-SKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIKEGV 315 NG IP+ GLGT+K + EV QA+ A+ GYRHID A +YGNE+ +G+AI K+ Sbjct: 12 NGVEIPLIGLGTYKMTDEHEVYQAIITALQNGYRHIDTAQIYGNEELIGKAI----KDSG 67 Query: 316 VTREDLFITSKLWNTFHRPDLVXGXLQETLDNLNVQYLDLYLI 444 V R+++F+TSK+WN H+ D + L L+ YLDL L+ Sbjct: 68 VPRKEIFLTSKIWNANHKYDAALQEIDNILKRLDTDYLDLCLV 110 >UniRef50_A3VHZ9 Cluster: Oxidoreductase; n=1; Rhodobacterales bacterium HTCC2654|Rep: Oxidoreductase - Rhodobacterales bacterium HTCC2654 Length = 278 Score = 91.1 bits (216), Expect = 4e-17 Identities = 45/111 (40%), Positives = 64/111 (57%) Frame = +1 Query: 121 PVVTFNNGESIPVFGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSK 300 P VT NG +P GLGTW E +AV AI+ GYR ID A Y NE VG+ Sbjct: 8 PTVTLANGVEMPQLGLGTWPMTDDEAAKAVATAIETGYRLIDTAENYKNETGVGQG---- 63 Query: 301 IKEGVVTREDLFITSKLWNTFHRPDLVXGXLQETLDNLNVQYLDLYLIHWP 453 I++ V R+++F+T+K+ +H D + +L+ L + Y+DL+LIHWP Sbjct: 64 IRDAGVARDEVFLTTKMNKQWHSVDGARRACEASLERLGLDYIDLFLIHWP 114 >UniRef50_Q8ZH36 Cluster: 2,5-diketo-D-gluconic acid reductase B; n=91; Proteobacteria|Rep: 2,5-diketo-D-gluconic acid reductase B - Yersinia pestis Length = 267 Score = 91.1 bits (216), Expect = 4e-17 Identities = 46/107 (42%), Positives = 65/107 (60%) Frame = +1 Query: 148 SIPVFGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIKEGVVTRE 327 SIPVFGLGT++ + V +V A+ +GYR ID A +Y NE VG+A I+E + R+ Sbjct: 2 SIPVFGLGTFRLQDQIVIDSVSQALTLGYRAIDTAQIYENEAPVGQA----IQESGINRD 57 Query: 328 DLFITSKLWNTFHRPDLVXGXLQETLDNLNVQYLDLYLIHWPQAYKE 468 +LFIT+K+W D + L+E++ L Y+DL LIHWP E Sbjct: 58 ELFITTKIWIANLSKDKLIPSLRESIQKLKTDYVDLTLIHWPSPNDE 104 >UniRef50_Q568D7 Cluster: Zgc:110366; n=7; Euteleostomi|Rep: Zgc:110366 - Danio rerio (Zebrafish) (Brachydanio rerio) Length = 289 Score = 90.6 bits (215), Expect = 5e-17 Identities = 59/158 (37%), Positives = 87/158 (55%), Gaps = 1/158 (0%) Frame = +1 Query: 121 PVVTFNNGESIPVFGLGTWKSKPGEVTQAVKDAI-DIGYRHIDCAYVYGNEKEVGEAITS 297 P V +NG +IP+ GLGT G +AV A+ + G RHID A YG E+ +G+A+T Sbjct: 14 PAVPLHNGLNIPILGLGT-SHYGGYSHEAVLYALQECGIRHIDTAKRYGCEEALGKAVT- 71 Query: 298 KIKEGVVTREDLFITSKLWNTFHRPDLVXGXLQETLDNLNVQYLDLYLIHWPQAYKEDGS 477 E V RE+L++T+KLW + +++ L V YLDLYL+HWP S Sbjct: 72 ---ESGVQREELWVTTKLWPGDYGYQSTKQACRDSRARLGVDYLDLYLMHWPD------S 122 Query: 478 LFPTXQSGKIQFSDXDYVDXWKAMEPLXKEGLVXSIGV 591 + P S +++ ++ W+A+E L EGL +IGV Sbjct: 123 MVPGRSSQEVR------LETWRALEELYDEGLCRAIGV 154 >UniRef50_Q17568 Cluster: Putative uncharacterized protein; n=1; Caenorhabditis elegans|Rep: Putative uncharacterized protein - Caenorhabditis elegans Length = 287 Score = 89.8 bits (213), Expect = 8e-17 Identities = 50/153 (32%), Positives = 89/153 (58%), Gaps = 2/153 (1%) Frame = +1 Query: 139 NGESIPVFGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIKEGVV 318 NG+ IP LGT+++K ++ AV +A+ +GYR D A Y NEK++G A+ + + + Sbjct: 6 NGQEIPKLALGTYEAKGDQLFAAVDEALKVGYRSFDTAKYYENEKDLGLALKTLLPRHNI 65 Query: 319 TREDLFITSKL--WNTFHRPDLVXGXLQETLDNLNVQYLDLYLIHWPQAYKEDGSLFPTX 492 ED+++TSK+ +++ + +L+ + E+L+ L+ +YLDL L+H+P+ + Sbjct: 66 CSEDIYLTSKVFPYSSKNAAELIRKDVNESLELLDRKYLDLVLVHYPRPLDTE----DLN 121 Query: 493 QSGKIQFSDXDYVDXWKAMEPLXKEGLVXSIGV 591 ++ K+ D W A+E L EG + SIGV Sbjct: 122 ENNKMYRK-----DTWIALEKLHAEGKIRSIGV 149 >UniRef50_A3VRL4 Cluster: Putative uncharacterized protein; n=1; Parvularcula bermudensis HTCC2503|Rep: Putative uncharacterized protein - Parvularcula bermudensis HTCC2503 Length = 278 Score = 89.4 bits (212), Expect = 1e-16 Identities = 41/101 (40%), Positives = 63/101 (62%) Frame = +1 Query: 151 IPVFGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIKEGVVTRED 330 IP G GTW+ + + + + AI+ GYRHID A +Y NEK+VGE IK+ + R++ Sbjct: 11 IPRLGFGTWQLEGEDARTSTRTAIETGYRHIDGAAIYKNEKKVGEG----IKDSGIPRDE 66 Query: 331 LFITSKLWNTFHRPDLVXGXLQETLDNLNVQYLDLYLIHWP 453 LF+T+K+WN + + E+LD L + Y++L L+HWP Sbjct: 67 LFVTTKIWNEDIQKGRHSEAVDESLDRLGLDYVNLILLHWP 107 >UniRef50_Q9A2X8 Cluster: Oxidoreductase, aldo/keto reductase family; n=3; Caulobacter|Rep: Oxidoreductase, aldo/keto reductase family - Caulobacter crescentus (Caulobacter vibrioides) Length = 279 Score = 89.0 bits (211), Expect = 1e-16 Identities = 45/118 (38%), Positives = 72/118 (61%), Gaps = 1/118 (0%) Frame = +1 Query: 106 MAPKIPVVTFNNGESIPVFGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGE 285 M+ +P V + +P G GTW+ + G V+ A++IGYRHID A +YGNE++VG Sbjct: 1 MSKLVPAVR-SGDVLMPALGFGTWQLENGTAVPLVEKALEIGYRHIDTAQIYGNERDVGA 59 Query: 286 AITSKIKEGVVTREDLFITSKLW-NTFHRPDLVXGXLQETLDNLNVQYLDLYLIHWPQ 456 A I+ V R+++F+T+K+W + F DL +++L+ L V +DL L+HWP+ Sbjct: 60 A----IRNSGVKRDEIFLTTKVWIDQFADGDLQRS-AEKSLEKLGVDQVDLLLLHWPK 112 >UniRef50_A1UEC5 Cluster: 2,5-didehydrogluconate reductase; n=20; Corynebacterineae|Rep: 2,5-didehydrogluconate reductase - Mycobacterium sp. (strain KMS) Length = 283 Score = 89.0 bits (211), Expect = 1e-16 Identities = 56/161 (34%), Positives = 81/161 (50%) Frame = +1 Query: 109 APKIPVVTFNNGESIPVFGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEA 288 A IP V+ N+G SIPV GLG + E ++V A++ GYR ID A VYGNE VG A Sbjct: 8 AAGIPSVSLNDGHSIPVLGLGVGELSEAEAERSVAAALEAGYRLIDTAAVYGNEAAVGRA 67 Query: 289 ITSKIKEGVVTREDLFITSKLWNTFHRPDLVXGXLQETLDNLNVQYLDLYLIHWPQAYKE 468 + + + RE++++T+KL + +L+ L + Y+DLYLIHW Sbjct: 68 VNA----SGIPREEIYVTTKLAVADQGFGTSQDAARASLERLGLDYVDLYLIHW------ 117 Query: 469 DGSLFPTXQSGKIQFSDXDYVDXWKAMEPLXKEGLVXSIGV 591 P GK Y+D W + ++G+ SIGV Sbjct: 118 -----PAGDHGK-------YIDSWGGLMKAKQDGVARSIGV 146 Score = 34.7 bits (76), Expect = 3.4 Identities = 13/34 (38%), Positives = 21/34 (61%) Frame = +3 Query: 594 NFNSKQLERLLQXATVKPVVNQVECHPLPHQKXL 695 NFN++ L ++ + P +NQ+E HPL +Q L Sbjct: 148 NFNAEHLSNIIDLSFFTPAINQIELHPLLNQAEL 181 >UniRef50_Q5UX52 Cluster: Oxidoreductase aldo/keto reductase family; n=1; Haloarcula marismortui|Rep: Oxidoreductase aldo/keto reductase family - Haloarcula marismortui (Halobacterium marismortui) Length = 274 Score = 89.0 bits (211), Expect = 1e-16 Identities = 44/104 (42%), Positives = 61/104 (58%) Frame = +1 Query: 142 GESIPVFGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIKEGVVT 321 G S+P GLGTW+ + V+ A+ +GYRHID A YGNE++VG + + V Sbjct: 8 GTSVPALGLGTWQLTGQSCRETVETALGMGYRHIDTAQAYGNERQVGLGMDA----AAVD 63 Query: 322 REDLFITSKLWNTFHRPDLVXGXLQETLDNLNVQYLDLYLIHWP 453 RED+F+T+KL + V +E+L+ L YLDL LIHWP Sbjct: 64 REDVFLTTKLDGSNRDERSVRRSTRESLNKLGTDYLDLLLIHWP 107 >UniRef50_P47137 Cluster: Probable oxidoreductase YJR096W; n=8; Saccharomycetales|Rep: Probable oxidoreductase YJR096W - Saccharomyces cerevisiae (Baker's yeast) Length = 282 Score = 89.0 bits (211), Expect = 1e-16 Identities = 57/165 (34%), Positives = 86/165 (52%), Gaps = 3/165 (1%) Frame = +1 Query: 106 MAPKIPVVTFNNGESIPVFGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGE 285 M PK +NG IP LGT+ + + V + + GYRH D A +YGNEKEVG+ Sbjct: 1 MVPKF--YKLSNGFKIPSIALGTYDIPRSQTAEIVYEGVKCGYRHFDTAVLYGNEKEVGD 58 Query: 286 AITSKIKE--GVVTREDLFITSKLWNTFHRPDLVXGXLQETLDNLN-VQYLDLYLIHWPQ 456 I + E G RE++F T+KLWN+ + +++ L+ ++ +QY+DL LIH P Sbjct: 59 GIIKWLNEDPGNHKREEIFYTTKLWNSQNGYKRAKAAIRQCLNEVSGLQYIDLLLIHSP- 117 Query: 457 AYKEDGSLFPTXQSGKIQFSDXDYVDXWKAMEPLXKEGLVXSIGV 591 + K++ ++ W+AM+ EGLV SIGV Sbjct: 118 -----------LEGSKLR------LETWRAMQEAVDEGLVKSIGV 145 >UniRef50_Q5BLA6 Cluster: Zgc:110782; n=2; Danio rerio|Rep: Zgc:110782 - Danio rerio (Zebrafish) (Brachydanio rerio) Length = 287 Score = 88.2 bits (209), Expect = 3e-16 Identities = 46/113 (40%), Positives = 69/113 (61%), Gaps = 1/113 (0%) Frame = +1 Query: 118 IPVVTFNNGESIPVFGLGTWKSKPGE-VTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAIT 294 +P V +G +P+ GLGT+K + E + Q+V A+ GYR D A VYGNE +G+ + Sbjct: 3 VPSVRLMSGTQMPLLGLGTYKLQDHEQLKQSVSCALQAGYRAFDTAAVYGNEAHLGQVLK 62 Query: 295 SKIKEGVVTREDLFITSKLWNTFHRPDLVXGXLQETLDNLNVQYLDLYLIHWP 453 + + + RED+FI SKL + H G L+ +L+ L+ +Y+DLYLIHWP Sbjct: 63 ELLPKYGLIREDVFIISKLAPSDHGLRAKEGCLR-SLEQLDCEYIDLYLIHWP 114 >UniRef50_Q235V6 Cluster: Oxidoreductase, aldo/keto reductase family protein; n=2; Tetrahymena thermophila SB210|Rep: Oxidoreductase, aldo/keto reductase family protein - Tetrahymena thermophila SB210 Length = 332 Score = 88.2 bits (209), Expect = 3e-16 Identities = 53/153 (34%), Positives = 85/153 (55%), Gaps = 1/153 (0%) Frame = +1 Query: 136 NNGESIPVFGLGTWK-SKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIKEG 312 NNG+ +P+ GLGT+ + E+T ++ A+D GYRHID A Y NE +GE++ + KEG Sbjct: 11 NNGQIMPLVGLGTYLLNSKEEMTNLLRTALDAGYRHIDTAVNYQNEAMIGESLKTIFKEG 70 Query: 313 VVTREDLFITSKLWNTFHRPDLVXGXLQETLDNLNVQYLDLYLIHWPQAYKEDGSLFPTX 492 +R+DLFI SK++ ++ + ++++L L + Y+DLY +H+P + Sbjct: 71 KYSRKDLFIVSKVFP--NKGINMLESVKKSLKELQLDYVDLYYLHFPLGF---------- 118 Query: 493 QSGKIQFSDXDYVDXWKAMEPLXKEGLVXSIGV 591 S K +F W +E + GL SIGV Sbjct: 119 LSEKEEFVHLPVHVAWAQLEEAHRLGLAKSIGV 151 >UniRef50_Q2U219 Cluster: Aldo/keto reductase family proteins; n=6; Pezizomycotina|Rep: Aldo/keto reductase family proteins - Aspergillus oryzae Length = 294 Score = 88.2 bits (209), Expect = 3e-16 Identities = 53/132 (40%), Positives = 73/132 (55%), Gaps = 9/132 (6%) Frame = +1 Query: 112 PKIPVVTFNNGESIPVFGLGT---WKSKPG------EVTQAVKDAIDIGYRHIDCAYVYG 264 P P V N+ SIP+ G GT W + G E+ +A+K AI +GYRH+D A VYG Sbjct: 7 PNTPRVKLNDNVSIPILGYGTGTAWYKQAGDDSVNRELVEAIKTAIRLGYRHLDGAEVYG 66 Query: 265 NEKEVGEAITSKIKEGVVTREDLFITSKLWNTFHRPDLVXGXLQETLDNLNVQYLDLYLI 444 E E+G A IKE + RE+LF+T+K+ + + ++L L + Y+DLYLI Sbjct: 67 TEAELGVA----IKESGIPREELFVTTKVITNIAD---IPSAIDQSLRKLQLNYVDLYLI 119 Query: 445 HWPQAYKEDGSL 480 H P K DG L Sbjct: 120 HSPFFAKSDGEL 131 Score = 36.3 bits (80), Expect = 1.1 Identities = 22/93 (23%), Positives = 39/93 (41%), Gaps = 3/93 (3%) Frame = +3 Query: 426 LGSVPDTLAPGLQGRRLSLPDRXIR*NPVXXXXXXXXXEGYGA---AXQRGSGXEHRSPN 596 + +P + L+ +L+ D + +P + + A Q G N Sbjct: 95 IADIPSAIDQSLRKLQLNYVDLYLIHSPFFAKSDGELQQAWAAMEKVQQAGKAKAIGVSN 154 Query: 597 FNSKQLERLLQXATVKPVVNQVECHPLPHQKXL 695 ++ LE L+ A + PV+NQ+E HP Q+ L Sbjct: 155 YHQSHLEATLKTAVIAPVINQIEHHPYLQQEEL 187 >UniRef50_UPI00006CA3CB Cluster: oxidoreductase, aldo/keto reductase family protein; n=3; Tetrahymena thermophila SB210|Rep: oxidoreductase, aldo/keto reductase family protein - Tetrahymena thermophila SB210 Length = 299 Score = 87.8 bits (208), Expect = 3e-16 Identities = 46/117 (39%), Positives = 69/117 (58%), Gaps = 1/117 (0%) Frame = +1 Query: 124 VVTFNNGESIPVFGLGTWKSKP-GEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSK 300 V+T +NG+ +P FGLG+ + + EVT ++ A+D+GYRHID A +Y NE+ +G A+ + Sbjct: 9 VITLSNGQKMPAFGLGSSRVQSVEEVTNLIRKALDVGYRHIDTAQMYENEQFIGAALKTI 68 Query: 301 IKEGVVTREDLFITSKLWNTFHRPDLVXGXLQETLDNLNVQYLDLYLIHWPQAYKED 471 EG RED+F+ +K + ++E L L V Y+DL LIH P A D Sbjct: 69 FGEGKYKREDIFLVTK--QASIKGVSCLEIMKEQLQKLQVDYVDLLLIHVPLAAPSD 123 Score = 34.3 bits (75), Expect = 4.4 Identities = 15/34 (44%), Positives = 20/34 (58%) Frame = +3 Query: 594 NFNSKQLERLLQXATVKPVVNQVECHPLPHQKXL 695 NFN + + LL +KP+VNQ+E H QK L Sbjct: 156 NFNCQMIIDLLAYCKIKPLVNQIELHVFNQQKNL 189 >UniRef50_Q043M4 Cluster: Aldo/keto reductase of diketogulonate reductase family; n=2; Lactobacillus|Rep: Aldo/keto reductase of diketogulonate reductase family - Lactobacillus gasseri (strain ATCC 33323 / DSM 20243) Length = 273 Score = 87.8 bits (208), Expect = 3e-16 Identities = 47/115 (40%), Positives = 66/115 (57%) Frame = +1 Query: 127 VTFNNGESIPVFGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIK 306 +T NN IP+FG GT++ P + QAV A + GYR ID A Y NE++VGEA +K Sbjct: 4 LTLNNDVKIPIFGFGTYEISPDQTKQAVLSAFEEGYRLIDTAQYYQNEQQVGEA----VK 59 Query: 307 EGVVTREDLFITSKLWNTFHRPDLVXGXLQETLDNLNVQYLDLYLIHWPQAYKED 471 + R+++FIT+K + D G L E+L + + Y DL LIHWP + D Sbjct: 60 ASGLNRDEVFITTKTMTDGYE-DTKIG-LDESLRRIGLDYFDLVLIHWPMGHDID 112 >UniRef50_Q5KD52 Cluster: Oxidoreductase, putative; n=1; Filobasidiella neoformans|Rep: Oxidoreductase, putative - Cryptococcus neoformans (Filobasidiella neoformans) Length = 321 Score = 87.8 bits (208), Expect = 3e-16 Identities = 64/159 (40%), Positives = 82/159 (51%), Gaps = 4/159 (2%) Frame = +1 Query: 127 VTFNNGESIPVFGLGTWKSKPGEVTQ-AVKDAIDIGYRHIDCA---YVYGNEKEVGEAIT 294 +T N+G IP GTWK P EVT V AID+G+ HID A VY NE+EVG+A Sbjct: 6 ITLNDGHRIPAIAFGTWKI-PKEVTPFQVGQAIDVGFDHIDTAQGRIVYHNEEEVGQA-- 62 Query: 295 SKIKEGVVTREDLFITSKLWNTFHRPDLVXGXLQETLDNLNVQYLDLYLIHWPQAYKEDG 474 IKE ++R L++T+K W+ + E+L+ L ++YLDLYLIH PQ K Sbjct: 63 --IKESGLSRNQLWVTTK-WSGIDGKG-ARQSIGESLEKLGLEYLDLYLIHSPQVTK--- 115 Query: 475 SLFPTXQSGKIQFSDXDYVDXWKAMEPLXKEGLVXSIGV 591 D WK +E L KEG SIGV Sbjct: 116 ---------------GDIKGAWKELETLQKEGKTKSIGV 139 Score = 39.9 bits (89), Expect = 0.089 Identities = 17/27 (62%), Positives = 21/27 (77%) Frame = +3 Query: 594 NFNSKQLERLLQXATVKPVVNQVECHP 674 +FN +QL+ LL ATVKPVVNQ+ HP Sbjct: 159 SFNKEQLQELLAHATVKPVVNQILLHP 185 >UniRef50_Q9X265 Cluster: Oxidoreductase, aldo/keto reductase family; n=2; Thermotoga|Rep: Oxidoreductase, aldo/keto reductase family - Thermotoga maritima Length = 274 Score = 87.4 bits (207), Expect = 5e-16 Identities = 51/113 (45%), Positives = 62/113 (54%), Gaps = 9/113 (7%) Frame = +1 Query: 142 GESIPVFGLGTWK---------SKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAIT 294 GE IP GLGTW S+ E+ + +K AI +GY HID A YG E I Sbjct: 10 GEEIPALGLGTWGIGGFETPDYSRDEEMVELLKTAIKMGYTHIDTAEYYGGG-HTEELIG 68 Query: 295 SKIKEGVVTREDLFITSKLWNTFHRPDLVXGXLQETLDNLNVQYLDLYLIHWP 453 IK+ REDLFI SK+W T R D + L+ TL L+ Y+DLYLIHWP Sbjct: 69 KAIKD--FRREDLFIVSKVWPTHLRRDDLLRSLENTLKRLDTDYVDLYLIHWP 119 >UniRef50_Q572D2 Cluster: Aldo-keto reductase, putative; n=1; Phytophthora infestans|Rep: Aldo-keto reductase, putative - Phytophthora infestans (Potato late blight fungus) Length = 255 Score = 87.4 bits (207), Expect = 5e-16 Identities = 44/122 (36%), Positives = 72/122 (59%), Gaps = 1/122 (0%) Frame = +1 Query: 106 MAPKIPVVTFNNGESIPVFGLGTWKSKPG-EVTQAVKDAIDIGYRHIDCAYVYGNEKEVG 282 M+ +P +G IP+ GLG ++S+PG E A+ ++ +GYRHID A +YGNE++VG Sbjct: 1 MSVNVPTKILPSGARIPMIGLGVYQSEPGPETYNAILTSLKLGYRHIDTAEIYGNEEDVG 60 Query: 283 EAITSKIKEGVVTREDLFITSKLWNTFHRPDLVXGXLQETLDNLNVQYLDLYLIHWPQAY 462 A +++ + RE++F+T+KL+ T + + D L + Y+ LYL+H P Sbjct: 61 RA----VRDSGIPREEIFVTTKLFTTNWGYSKALAAGKASNDRLGIVYIYLYLLHAPGPP 116 Query: 463 KE 468 KE Sbjct: 117 KE 118 Score = 33.9 bits (74), Expect = 5.9 Identities = 15/27 (55%), Positives = 17/27 (62%) Frame = +3 Query: 594 NFNSKQLERLLQXATVKPVVNQVECHP 674 NFN L L + A +KP VNQVE HP Sbjct: 142 NFNETLLATLRKTAHIKPAVNQVELHP 168 >UniRef50_Q18483 Cluster: Putative uncharacterized protein; n=2; Caenorhabditis|Rep: Putative uncharacterized protein - Caenorhabditis elegans Length = 287 Score = 87.4 bits (207), Expect = 5e-16 Identities = 52/149 (34%), Positives = 78/149 (52%), Gaps = 1/149 (0%) Frame = +1 Query: 148 SIPVFGLGTWKSKPGEVTQAVKDA-IDIGYRHIDCAYVYGNEKEVGEAITSKIKEGVVTR 324 ++P+ G+GTW+ + E+ + V DA GYR ID A VY NE ++G + + + R Sbjct: 10 NMPLIGIGTWQVQKEEILRQVIDAGFKEGYRFIDTAQVYNNEAKIGRILEKLLPANGLKR 69 Query: 325 EDLFITSKLWNTFHRPDLVXGXLQETLDNLNVQYLDLYLIHWPQAYKEDGSLFPTXQSGK 504 ED++ITSKL + ++E+L NL V+YLDL LIHWP GS + Sbjct: 70 EDIWITSKLAPSNAGVKKARESIEESLSNLKVEYLDLLLIHWP------GSSLKSENPAN 123 Query: 505 IQFSDXDYVDXWKAMEPLXKEGLVXSIGV 591 + V+ W M + EG + S+GV Sbjct: 124 KKLR----VESWNVMCEMMAEGKLRSVGV 148 Score = 33.5 bits (73), Expect = 7.8 Identities = 17/34 (50%), Positives = 19/34 (55%) Frame = +3 Query: 594 NFNSKQLERLLQXATVKPVVNQVECHPLPHQKXL 695 NF LE L + + V P VNQVE HP HQ L Sbjct: 150 NFEICHLEELKKDSNVVPAVNQVEYHPHFHQDDL 183 >UniRef50_A0AWM8 Cluster: Aldo/keto reductase; n=4; Actinomycetales|Rep: Aldo/keto reductase - Arthrobacter sp. (strain FB24) Length = 287 Score = 87.0 bits (206), Expect = 6e-16 Identities = 58/161 (36%), Positives = 78/161 (48%) Frame = +1 Query: 109 APKIPVVTFNNGESIPVFGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEA 288 A IP + +G +IP GLGTW E AV+ A+ GYR +D A+ Y NE+ VG Sbjct: 10 ASDIPRLKLPHGHTIPRLGLGTWPMLEDECETAVRFALQSGYRLVDTAFQYRNEEAVGRG 69 Query: 289 ITSKIKEGVVTREDLFITSKLWNTFHRPDLVXGXLQETLDNLNVQYLDLYLIHWPQAYKE 468 I+ V R +LFI+SK H D V E+L L + +LD+++ HW Sbjct: 70 ----IRTAGVPRSELFISSKFNKESHSIDGVQRAYDESLRKLGLDHLDMFMCHW------ 119 Query: 469 DGSLFPTXQSGKIQFSDXDYVDXWKAMEPLXKEGLVXSIGV 591 P GK YVD WK + L +EG V +IGV Sbjct: 120 -----PVPALGK-------YVDAWKGLVKLLEEGRVKAIGV 148 >UniRef50_UPI00005A2CCB Cluster: PREDICTED: similar to Aldose reductase (AR) (Aldehyde reductase); n=1; Canis lupus familiaris|Rep: PREDICTED: similar to Aldose reductase (AR) (Aldehyde reductase) - Canis familiaris Length = 182 Score = 86.6 bits (205), Expect = 8e-16 Identities = 39/80 (48%), Positives = 53/80 (66%) Frame = +1 Query: 127 VTFNNGESIPVFGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIK 306 + NG +P+ GL TWKS P +VT+AVK +D+GY HIDC + N++EVG A+ K+K Sbjct: 23 LVLGNGIKVPIMGLATWKSPPSKVTEAVKVVMDLGYCHIDCTHKLQNKREVGLAVQEKLK 82 Query: 307 EGVVTREDLFITSKLWNTFH 366 V REDL I S+L +T H Sbjct: 83 GQGVKREDLSILSELQHTHH 102 >UniRef50_Q6F7K7 Cluster: 2,5-diketo-D-gluconate reductase; n=20; Bacteria|Rep: 2,5-diketo-D-gluconate reductase - Acinetobacter sp. (strain ADP1) Length = 297 Score = 86.6 bits (205), Expect = 8e-16 Identities = 54/158 (34%), Positives = 80/158 (50%) Frame = +1 Query: 118 IPVVTFNNGESIPVFGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITS 297 IP + ++G SIP G GT+ K + + A+ GYR +D A+ Y NE VG A+ Sbjct: 22 IPDLILHDGHSIPALGFGTYTLKGQQGVDTMLRALGHGYRMLDSAFNYENEGAVGAAV-- 79 Query: 298 KIKEGVVTREDLFITSKLWNTFHRPDLVXGXLQETLDNLNVQYLDLYLIHWPQAYKEDGS 477 ++ + R+++FITSKL H D ++E+L + YLDLYLIHW Sbjct: 80 --RQSGLLRDEIFITSKLPGRHHAYDKAMETIEESLYRMQFDYLDLYLIHW--------- 128 Query: 478 LFPTXQSGKIQFSDXDYVDXWKAMEPLXKEGLVXSIGV 591 P Q G Y++ W+A+ K+G + SIGV Sbjct: 129 --PNPQQGL-------YIEAWQALIDAQKKGYIRSIGV 157 >UniRef50_A5VK30 Cluster: 2,5-didehydrogluconate reductase; n=2; Lactobacillus reuteri|Rep: 2,5-didehydrogluconate reductase - Lactobacillus reuteri F275 Length = 300 Score = 86.6 bits (205), Expect = 8e-16 Identities = 55/158 (34%), Positives = 75/158 (47%), Gaps = 1/158 (0%) Frame = +1 Query: 121 PVVTFNNGESIPVFGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSK 300 P + NNG IP GLG WK+ E Q VK+AI Y ID A YGNE VG+ I Sbjct: 11 PKIKLNNGHLIPQLGLGVWKASLAETQQMVKEAIMNDYVLIDTAKQYGNEAAVGQGIQDG 70 Query: 301 IKEGVVTREDLFITSKLWNTFHRP-DLVXGXLQETLDNLNVQYLDLYLIHWPQAYKEDGS 477 K R+ +F+T+K++N D + + E L L Y+DL L+HWP K Sbjct: 71 FKATGRKRDSIFLTTKIFNGDQGDYDKLRQAVNEQLKKLQTNYVDLLLLHWPVNDK---- 126 Query: 478 LFPTXQSGKIQFSDXDYVDXWKAMEPLXKEGLVXSIGV 591 Y + W+A+E + K+G +IGV Sbjct: 127 ----------------YNESWRALEDIYKDGQAKAIGV 148 Score = 38.3 bits (85), Expect = 0.27 Identities = 16/39 (41%), Positives = 24/39 (61%) Frame = +3 Query: 594 NFNSKQLERLLQXATVKPVVNQVECHPLPHQKXLXSSVR 710 NFN +++ LL A +KP +NQ+E +PL HQ + R Sbjct: 150 NFNVERMTDLLDHAKIKPAINQIEFNPLIHQPKIVKFCR 188 >UniRef50_UPI0000DB6EE9 Cluster: PREDICTED: similar to C35D10.6; n=2; Endopterygota|Rep: PREDICTED: similar to C35D10.6 - Apis mellifera Length = 292 Score = 86.2 bits (204), Expect = 1e-15 Identities = 51/157 (32%), Positives = 85/157 (54%), Gaps = 2/157 (1%) Frame = +1 Query: 127 VTFNNGESIPVFGLGTWKSKPGE-VTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKI 303 V ++G +P+ G GT+K + E V Q V +++++G+R ID A Y NE+++G A+ + + Sbjct: 8 VCLSSGYDMPLIGFGTYKIQGRELVYQVVDESLNVGFRSIDTAVGYRNEEDIGYALKNLL 67 Query: 304 KEGVVTREDLFITSKLWNTFH-RPDLVXGXLQETLDNLNVQYLDLYLIHWPQAYKEDGSL 480 + + R D+FIT+KL + + P + +Q++L N Y+DLYLIHWP A + Sbjct: 68 PKYNLQRSDIFITTKLPPSVNGDPKGIEQCVQKSLKAFNTTYIDLYLIHWPGATR----- 122 Query: 481 FPTXQSGKIQFSDXDYVDXWKAMEPLXKEGLVXSIGV 591 P + W + L K+G + SIGV Sbjct: 123 IPETSTNNPSLR----AKTWNKLVDLKKQGFIRSIGV 155 >UniRef50_A7ALH6 Cluster: Putative uncharacterized protein; n=1; Parabacteroides merdae ATCC 43184|Rep: Putative uncharacterized protein - Parabacteroides merdae ATCC 43184 Length = 301 Score = 86.2 bits (204), Expect = 1e-15 Identities = 50/113 (44%), Positives = 65/113 (57%) Frame = +1 Query: 115 KIPVVTFNNGESIPVFGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAIT 294 K+P V NNG +P G+GT+ K + V AI +G+R ID A YGNEKEVGE I Sbjct: 28 KVPTVKLNNGMEMPQLGVGTFLVKDN-AAERVCHAIKVGFRLIDTAQGYGNEKEVGEGIC 86 Query: 295 SKIKEGVVTREDLFITSKLWNTFHRPDLVXGXLQETLDNLNVQYLDLYLIHWP 453 + G+ RE LFIT+K+ R V L ++L +L Y+DL LIHWP Sbjct: 87 ---RSGIDRRE-LFITTKVNTMEMRGGTVRQSLDKSLADLGTDYIDLVLIHWP 135 Score = 35.9 bits (79), Expect = 1.5 Identities = 14/27 (51%), Positives = 19/27 (70%) Frame = +3 Query: 594 NFNSKQLERLLQXATVKPVVNQVECHP 674 NFN L+ LL+ A ++PVVNQ+E P Sbjct: 163 NFNPHHLDELLEYARIRPVVNQIEIEP 189 >UniRef50_Q1Q8W8 Cluster: Aldo/keto reductase; n=1; Psychrobacter cryohalolentis K5|Rep: Aldo/keto reductase - Psychrobacter cryohalolentis (strain K5) Length = 282 Score = 85.8 bits (203), Expect = 1e-15 Identities = 41/104 (39%), Positives = 62/104 (59%), Gaps = 2/104 (1%) Frame = +1 Query: 148 SIPVFGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIKEGVVTRE 327 +IPV GLGTW+S + V + +GY HID A YGNE EVG+ IK+ V R+ Sbjct: 15 NIPVLGLGTWQSTGQDCIDVVSQGLRMGYEHIDTAQAYGNEVEVGKG----IKQSGVARD 70 Query: 328 DLFITSKLW--NTFHRPDLVXGXLQETLDNLNVQYLDLYLIHWP 453 F+T+K++ + P+ + + +L+NL+ Y+DL L+HWP Sbjct: 71 KFFLTTKIFPDDMKFEPEKLVAAAKRSLENLDTDYVDLLLLHWP 114 >UniRef50_Q0SFM4 Cluster: Probable 2,5-didehydrogluconate reductase; n=1; Rhodococcus sp. RHA1|Rep: Probable 2,5-didehydrogluconate reductase - Rhodococcus sp. (strain RHA1) Length = 265 Score = 85.8 bits (203), Expect = 1e-15 Identities = 45/101 (44%), Positives = 60/101 (59%) Frame = +1 Query: 151 IPVFGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIKEGVVTRED 330 IP GLGTW + T+AV I+ GYR ID A +Y NE VG A+ E V RE+ Sbjct: 4 IPPLGLGTWPLTGPDATRAVLSGIEAGYRLIDTATIYDNEDAVGVALA----ECGVPREE 59 Query: 331 LFITSKLWNTFHRPDLVXGXLQETLDNLNVQYLDLYLIHWP 453 LF+T+KL + H + G ++ +L NL + LDL+LIHWP Sbjct: 60 LFVTTKLRGSDHVSGDIRGAVERSLKNLGLDRLDLFLIHWP 100 >UniRef50_A5ZYE6 Cluster: Putative uncharacterized protein; n=1; Ruminococcus obeum ATCC 29174|Rep: Putative uncharacterized protein - Ruminococcus obeum ATCC 29174 Length = 263 Score = 85.8 bits (203), Expect = 1e-15 Identities = 47/102 (46%), Positives = 61/102 (59%), Gaps = 1/102 (0%) Frame = +1 Query: 151 IPVFGLGTWKSKPG-EVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIKEGVVTRE 327 +P+ GLG +K+ E A+ A+ GYR +D A Y NE+ VG I K GV R+ Sbjct: 1 MPLLGLGLYKTTDAVEAEDAIAAAVQNGYRLLDTASAYKNEEFVGCGIA---KCGV-PRK 56 Query: 328 DLFITSKLWNTFHRPDLVXGXLQETLDNLNVQYLDLYLIHWP 453 DLFIT+K+WN R V G Q +LD L + Y+DLYLIHWP Sbjct: 57 DLFITTKIWNNAQRLGDVEGAFQRSLDRLGLDYIDLYLIHWP 98 Score = 39.1 bits (87), Expect = 0.16 Identities = 16/34 (47%), Positives = 22/34 (64%) Frame = +3 Query: 594 NFNSKQLERLLQXATVKPVVNQVECHPLPHQKXL 695 NF + LE L + + + P VNQ+ECHPL + K L Sbjct: 126 NFEIRHLEELRRVSGIVPAVNQIECHPLCYPKEL 159 >UniRef50_A4YQ04 Cluster: 2,5-diketo-D-gluconate reductase B; n=15; Proteobacteria|Rep: 2,5-diketo-D-gluconate reductase B - Bradyrhizobium sp. (strain ORS278) Length = 273 Score = 85.8 bits (203), Expect = 1e-15 Identities = 40/104 (38%), Positives = 60/104 (57%) Frame = +1 Query: 142 GESIPVFGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIKEGVVT 321 G +P GLGT++ + AV+ A+ +GYRHID A +Y NE +G A+ + + Sbjct: 8 GVRLPKLGLGTFRMQGTVCRDAVESALALGYRHIDTAEMYANEDAIGAALAA----AQIA 63 Query: 322 REDLFITSKLWNTFHRPDLVXGXLQETLDNLNVQYLDLYLIHWP 453 REDL +T+K+W PD + +L L + ++DLYLIHWP Sbjct: 64 REDLHVTTKVWPENLAPDAIRRAFDTSLKKLRLDFVDLYLIHWP 107 >UniRef50_Q11BF8 Cluster: Aldo/keto reductase; n=12; Bacteria|Rep: Aldo/keto reductase - Mesorhizobium sp. (strain BNC1) Length = 308 Score = 85.4 bits (202), Expect = 2e-15 Identities = 40/105 (38%), Positives = 64/105 (60%) Frame = +1 Query: 139 NGESIPVFGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIKEGVV 318 +G +P+ GLG +++ P E T AV++A+ +GYRHID A YGNE+EVGE I+ + Sbjct: 25 SGVEMPMIGLGVFQTPPDETTAAVEEALRLGYRHIDTAAAYGNEREVGEG----IRRAGI 80 Query: 319 TREDLFITSKLWNTFHRPDLVXGXLQETLDNLNVQYLDLYLIHWP 453 R+++FI +K+W + + D ++ L V +DL L+H P Sbjct: 81 ARDEVFIETKIWISDYGYDETLHAFDKSAGKLGVDQIDLLLLHQP 125 Score = 34.3 bits (75), Expect = 4.4 Identities = 15/34 (44%), Positives = 20/34 (58%) Frame = +3 Query: 594 NFNSKQLERLLQXATVKPVVNQVECHPLPHQKXL 695 NF + L RLL ++ P VNQ+E HP Q+ L Sbjct: 156 NFMPEHLTRLLTETSIVPAVNQIEVHPYFQQRAL 189 >UniRef50_Q7VHE1 Cluster: Putative uncharacterized protein; n=1; Helicobacter hepaticus|Rep: Putative uncharacterized protein - Helicobacter hepaticus Length = 270 Score = 85.0 bits (201), Expect = 2e-15 Identities = 44/124 (35%), Positives = 72/124 (58%) Frame = +1 Query: 127 VTFNNGESIPVFGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIK 306 +T NNG +P+ GLGT+ +A+ +AI++GYR D A +Y NE E+G AI + +K Sbjct: 4 LTLNNGVKMPILGLGTYSLTGKAGQKAMSEAIEVGYRLFDSAQMYNNEAELGAAINAAVK 63 Query: 307 EGVVTREDLFITSKLWNTFHRPDLVXGXLQETLDNLNVQYLDLYLIHWPQAYKEDGSLFP 486 G + RE+ FI +KL + DL ++++L L + Y+D LIH P Y + +++ Sbjct: 64 GG-IKREEFFIQTKLLES-SSEDLAKKSIEKSLKTLGLDYIDSLLIHMP--YSQSKAMYR 119 Query: 487 TXQS 498 +S Sbjct: 120 AMES 123 >UniRef50_Q927P9 Cluster: Lin2739 protein; n=12; Bacteria|Rep: Lin2739 protein - Listeria innocua Length = 283 Score = 84.6 bits (200), Expect = 3e-15 Identities = 47/110 (42%), Positives = 62/110 (56%), Gaps = 1/110 (0%) Frame = +1 Query: 127 VTFNNGESIPVFGLGTWK-SKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKI 303 V NNG +P+ G GT++ + GE QAVK+AI GYRHID A Y NE+ VG I + Sbjct: 4 VKLNNGIEVPILGFGTYQITDAGEAEQAVKEAIAAGYRHIDTAQSYMNEEAVGRGIAA-- 61 Query: 304 KEGVVTREDLFITSKLWNTFHRPDLVXGXLQETLDNLNVQYLDLYLIHWP 453 V R++LFIT+K+W V +L L + Y+DL LIH P Sbjct: 62 --SGVDRKELFITTKIWVENVSYKGVMSSFDRSLKRLGLDYIDLLLIHQP 109 >UniRef50_P91997 Cluster: Putative uncharacterized protein; n=4; Caenorhabditis|Rep: Putative uncharacterized protein - Caenorhabditis elegans Length = 297 Score = 84.2 bits (199), Expect = 4e-15 Identities = 50/153 (32%), Positives = 80/153 (52%), Gaps = 1/153 (0%) Frame = +1 Query: 136 NNGESIPVFGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIKEGV 315 N+G +IP G GT+K V A+ A+ GYR D A Y NEKE+GEA+ + + Sbjct: 16 NSGYNIPFVGFGTYKVTGENVPPAIDAALTAGYRMFDTAKYYLNEKELGEALKILLPKHG 75 Query: 316 VTREDLFITSKLW-NTFHRPDLVXGXLQETLDNLNVQYLDLYLIHWPQAYKEDGSLFPTX 492 ++R D+F+TSK + + + + G ++E+L +L Y+D+YL+H+P+ D Sbjct: 76 LSRSDVFLTSKFFPESKNCREACRGFVEESLQSLQTDYIDMYLVHYPKPNDSDNDDVNNA 135 Query: 493 QSGKIQFSDXDYVDXWKAMEPLXKEGLVXSIGV 591 + KI + + +E G V SIGV Sbjct: 136 EYRKIAY---------EVLEEAKAAGKVRSIGV 159 >UniRef50_Q5XJM7 Cluster: Zgc:101765; n=5; Eumetazoa|Rep: Zgc:101765 - Danio rerio (Zebrafish) (Brachydanio rerio) Length = 288 Score = 83.8 bits (198), Expect = 6e-15 Identities = 46/112 (41%), Positives = 65/112 (58%), Gaps = 1/112 (0%) Frame = +1 Query: 121 PVVTFNNGESIPVFGLGTWKSKPGEVT-QAVKDAIDIGYRHIDCAYVYGNEKEVGEAITS 297 P V NN +P+ GLGT++ + E T AV A+ GYR D A VY NE +G A+ Sbjct: 6 PSVLLNNDIQMPLLGLGTFRLQGQEDTYSAVDAALKAGYRAFDTAAVYRNEAHLGHALRC 65 Query: 298 KIKEGVVTREDLFITSKLWNTFHRPDLVXGXLQETLDNLNVQYLDLYLIHWP 453 + + ++RED+FITSKL + Q++L+ L + Y+DLYLIHWP Sbjct: 66 LLPKHGLSREDVFITSKL-GPKDQGSKARNGCQKSLEQLGLGYIDLYLIHWP 116 >UniRef50_Q927E1 Cluster: Lin2848 protein; n=13; Listeria|Rep: Lin2848 protein - Listeria innocua Length = 280 Score = 83.0 bits (196), Expect = 1e-14 Identities = 51/153 (33%), Positives = 79/153 (51%), Gaps = 1/153 (0%) Frame = +1 Query: 136 NNGESIPVFGLGTWK-SKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIKEG 312 NNG +P G G +K + + A++ A+D+GYR D A Y NEKE+G+ S Sbjct: 12 NNGIEMPRHGFGVYKLTDEQRMRTALETAVDVGYRLFDTASFYHNEKELGDFFASS---- 67 Query: 313 VVTREDLFITSKLWNTFHRPDLVXGXLQETLDNLNVQYLDLYLIHWPQAYKEDGSLFPTX 492 + R++ F+T+K+WNT D +++ L + +DLYL+HWP K+D Sbjct: 68 GLKRDEFFVTTKMWNTEQGYDETLRAFEKSQKKLQLDQVDLYLVHWP---KQD------- 117 Query: 493 QSGKIQFSDXDYVDXWKAMEPLXKEGLVXSIGV 591 + + W+A+E L EGLV +IGV Sbjct: 118 ----------TFFETWRAVEKLYDEGLVRAIGV 140 >UniRef50_Q8EVT8 Cluster: Oxidoreductase-aldo/keto reductase family; n=1; Mycoplasma penetrans|Rep: Oxidoreductase-aldo/keto reductase family - Mycoplasma penetrans Length = 299 Score = 83.0 bits (196), Expect = 1e-14 Identities = 44/113 (38%), Positives = 66/113 (58%), Gaps = 2/113 (1%) Frame = +1 Query: 121 PVVTFNNGESIPVFGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSK 300 P++T N+G IP+ GLGT A+K A++IG R D A +YGNEKEVGE Sbjct: 35 PLLTLNDGYQIPIIGLGTTSLHNQTCKNAIKAALEIGIRLFDTASLYGNEKEVGET---- 90 Query: 301 IKEGVVTREDLFITSKLW--NTFHRPDLVXGXLQETLDNLNVQYLDLYLIHWP 453 I+E + R ++F+ +KL+ F P+ ++E L+ LN Y+D+ L+H P Sbjct: 91 IRESNINRNEIFVITKLYPGAQFANPEKA---IEEALNKLNTDYIDMMLLHHP 140 >UniRef50_A3WP89 Cluster: Aldo/keto reductase; n=1; Idiomarina baltica OS145|Rep: Aldo/keto reductase - Idiomarina baltica OS145 Length = 263 Score = 83.0 bits (196), Expect = 1e-14 Identities = 44/106 (41%), Positives = 60/106 (56%) Frame = +1 Query: 151 IPVFGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIKEGVVTRED 330 IP FG+GT++ + E+T V AID+GY HID A YGNE +VG+A+ T +D Sbjct: 2 IPQFGMGTFRLEGQELTDLVSAAIDMGYEHIDTAQFYGNEADVGKALAQH------TNKD 55 Query: 331 LFITSKLWNTFHRPDLVXGXLQETLDNLNVQYLDLYLIHWPQAYKE 468 +F+T+K+W V LQ + D L +DL LIHWP E Sbjct: 56 VFVTTKVWYEKLAYQDVLDSLQVSRDKLQRDTIDLALIHWPSPNDE 101 >UniRef50_A2RMU6 Cluster: Oxidoreductase, aldo/keto reductase family; n=3; Lactococcus lactis|Rep: Oxidoreductase, aldo/keto reductase family - Lactococcus lactis subsp. cremoris (strain MG1363) Length = 281 Score = 83.0 bits (196), Expect = 1e-14 Identities = 46/108 (42%), Positives = 68/108 (62%), Gaps = 1/108 (0%) Frame = +1 Query: 127 VTFNNGESIPVFGLGTWKSKPGEVTQ-AVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKI 303 + N+G IP FGLG ++ GE T+ AVK+A+ +GYRHID A+ Y NE+ VG AI S Sbjct: 5 IVLNDGNIIPQFGLGVYQIPEGEATENAVKEALRLGYRHIDTAHAYQNERSVGRAIHS-- 62 Query: 304 KEGVVTREDLFITSKLWNTFHRPDLVXGXLQETLDNLNVQYLDLYLIH 447 G+ E ++ITSKLW + + D ++ L+ LN++ +DL L+H Sbjct: 63 -SGIPISE-IWITSKLWPSDY--DDASQAIERMLELLNLKQIDLLLLH 106 >UniRef50_UPI000155CAC7 Cluster: PREDICTED: hypothetical protein; n=1; Ornithorhynchus anatinus|Rep: PREDICTED: hypothetical protein - Ornithorhynchus anatinus Length = 419 Score = 82.6 bits (195), Expect = 1e-14 Identities = 53/126 (42%), Positives = 72/126 (57%), Gaps = 1/126 (0%) Frame = +1 Query: 85 AAKLINKMAPKIPVVTFNNGESIPVFGLGTWKSKPGEVTQAVKDAI-DIGYRHIDCAYVY 261 A+ + K P +P V NG +IP+ GLGT G AV A+ + G RHID A Y Sbjct: 2 ASATLGKGLP-VPTVPLANGLNIPILGLGT-SHVGGYSHDAVIYALKECGIRHIDTAKRY 59 Query: 262 GNEKEVGEAITSKIKEGVVTREDLFITSKLWNTFHRPDLVXGXLQETLDNLNVQYLDLYL 441 G E +G+AI +E V RE+L+IT+KLW T + + E+ + L V+YLDL+L Sbjct: 60 GCELLLGKAI----QESGVKREELWITTKLWLTDYGYESAKQSCLESCNRLGVEYLDLFL 115 Query: 442 IHWPQA 459 IHWP A Sbjct: 116 IHWPDA 121 >UniRef50_A2QB88 Cluster: Contig An01c0460, complete genome. precursor; n=1; Aspergillus niger|Rep: Contig An01c0460, complete genome. precursor - Aspergillus niger Length = 351 Score = 82.6 bits (195), Expect = 1e-14 Identities = 58/161 (36%), Positives = 82/161 (50%), Gaps = 13/161 (8%) Frame = +1 Query: 148 SIPVFGLGTWKSKPGE--VTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIKEGVVT 321 + P GLGT++ G V +AV A+ GYRHID A YGNE EVGEA IKE + Sbjct: 45 TFPAVGLGTFQGDAGNRGVKEAVLQALRCGYRHIDTATAYGNEIEVGEA----IKESRIP 100 Query: 322 REDLFITSKLWNTFHRPDLVXGXLQETLDNLNVQY-LDLYLIHWPQAYKEDGSLFPTXQS 498 RE++ +T+KL T+HR V L +L+ L + Y L ++L + +Y + P + Sbjct: 101 REEIIVTTKLAQTWHRVSDVERALDLSLERLQLNYGLSMHL-YSASSYSVPHAYSPGPDN 159 Query: 499 GKIQFSD----------XDYVDXWKAMEPLXKEGLVXSIGV 591 I+ + DY W AME L +G + IGV Sbjct: 160 NTIRHPNGKPIIDHELSRDYPSTWAAMESLVDKGKLKMIGV 200 Score = 37.5 bits (83), Expect = 0.48 Identities = 16/27 (59%), Positives = 19/27 (70%) Frame = +3 Query: 594 NFNSKQLERLLQXATVKPVVNQVECHP 674 NFN +LERLL A + P VNQ+E HP Sbjct: 202 NFNILKLERLLGSARIPPAVNQIELHP 228 >UniRef50_Q8Y463 Cluster: Lmo2592 protein; n=40; Bacteria|Rep: Lmo2592 protein - Listeria monocytogenes Length = 283 Score = 82.2 bits (194), Expect = 2e-14 Identities = 46/110 (41%), Positives = 60/110 (54%), Gaps = 1/110 (0%) Frame = +1 Query: 127 VTFNNGESIPVFGLGTWK-SKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKI 303 V NNG +P+ G GT++ + E AVKDAI GYRHID A Y NE+ VG I + Sbjct: 4 VKLNNGVEVPILGFGTYQITDAAEAEHAVKDAIKAGYRHIDTAQSYMNEEAVGRGIAA-- 61 Query: 304 KEGVVTREDLFITSKLWNTFHRPDLVXGXLQETLDNLNVQYLDLYLIHWP 453 V R++LFIT+K+W V +L L + Y+DL LIH P Sbjct: 62 --SGVDRKELFITTKIWVENVSYKGVMSSFDRSLKRLGLDYVDLLLIHQP 109 >UniRef50_Q8G7K9 Cluster: Dehydrogenase or reductase protein; n=4; Bifidobacterium|Rep: Dehydrogenase or reductase protein - Bifidobacterium longum Length = 289 Score = 82.2 bits (194), Expect = 2e-14 Identities = 50/158 (31%), Positives = 73/158 (46%) Frame = +1 Query: 118 IPVVTFNNGESIPVFGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITS 297 +P + +G SIP GLG + V V+ A++ GYRHID A Y NE VG A+ + Sbjct: 11 VPDIALKDGHSIPQVGLGVLRIDDEGVVPVVESALEAGYRHIDGAAGYNNEAGVGRALAA 70 Query: 298 KIKEGVVTREDLFITSKLWNTFHRPDLVXGXLQETLDNLNVQYLDLYLIHWPQAYKEDGS 477 RE L++T+KL ++ D +L L + Y+D+Y+IHWP + Sbjct: 71 SGYNKGAKRETLWVTTKLRDSQQGYDSALKAFDNSLKLLQLDYVDMYMIHWPTPF----- 125 Query: 478 LFPTXQSGKIQFSDXDYVDXWKAMEPLXKEGLVXSIGV 591 D D WKA L EG+ ++GV Sbjct: 126 -------------DWRSTDTWKAFVKLRDEGMARTLGV 150 >UniRef50_P91021 Cluster: Putative uncharacterized protein; n=1; Caenorhabditis elegans|Rep: Putative uncharacterized protein - Caenorhabditis elegans Length = 134 Score = 82.2 bits (194), Expect = 2e-14 Identities = 43/85 (50%), Positives = 53/85 (62%) Frame = +1 Query: 127 VTFNNGESIPVFGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIK 306 +T +N S+P GLGTW+S +V AVK A+ GY ID A Y NE+ +G AI I Sbjct: 48 LTLSNAHSMPAVGLGTWQSNAEDVISAVKAAVKNGYSLIDTASGYNNEEFIGTAIKEVIA 107 Query: 307 EGVVTREDLFITSKLWNTFHRPDLV 381 EGVV REDLFIT+K+ N F LV Sbjct: 108 EGVVKREDLFITTKVPNLFSSLRLV 132 >UniRef50_Q11DV1 Cluster: Aldo/keto reductase; n=10; Alphaproteobacteria|Rep: Aldo/keto reductase - Mesorhizobium sp. (strain BNC1) Length = 274 Score = 81.8 bits (193), Expect = 2e-14 Identities = 37/105 (35%), Positives = 59/105 (56%) Frame = +1 Query: 139 NGESIPVFGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIKEGVV 318 +G +IP G G ++ EV + + A++ G+RH D A +Y NE +G A+ + Sbjct: 7 HGATIPALGFGVFRMSDAEVERIIPAALEAGFRHFDTAQIYQNEAALGRAL----ERAGA 62 Query: 319 TREDLFITSKLWNTFHRPDLVXGXLQETLDNLNVQYLDLYLIHWP 453 REDLF+T+K+W + D + E+L+ L V +DL L+HWP Sbjct: 63 RREDLFLTTKVWVDNYSADKFAASVDESLEKLKVDQVDLLLLHWP 107 >UniRef50_Q5V663 Cluster: Aldehyde reductase; n=6; Halobacteriaceae|Rep: Aldehyde reductase - Haloarcula marismortui (Halobacterium marismortui) Length = 279 Score = 81.8 bits (193), Expect = 2e-14 Identities = 41/113 (36%), Positives = 63/113 (55%), Gaps = 1/113 (0%) Frame = +1 Query: 151 IPVFGLGTWKSKPGE-VTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIKEGVVTRE 327 +P+ GLGTW+++ E ++V+ A++ GYRHID A Y NE VG+ I + V R+ Sbjct: 17 MPMLGLGTWQNEDAEQCAESVRTALEAGYRHIDTAQAYDNESAVGDGIAA----ADVDRD 72 Query: 328 DLFITSKLWNTFHRPDLVXGXLQETLDNLNVQYLDLYLIHWPQAYKEDGSLFP 486 D+F+ +K+W + D V +E+LD L V +DL +HW E P Sbjct: 73 DIFLATKVWISNLSHDDVIETTEESLDKLGVDSVDLLYVHWAAGEYEPEETLP 125 >UniRef50_A7D6Q0 Cluster: Aldo/keto reductase; n=1; Halorubrum lacusprofundi ATCC 49239|Rep: Aldo/keto reductase - Halorubrum lacusprofundi ATCC 49239 Length = 309 Score = 81.8 bits (193), Expect = 2e-14 Identities = 44/131 (33%), Positives = 69/131 (52%), Gaps = 3/131 (2%) Frame = +1 Query: 70 RSSQAAAKLINKMAPK---IPVVTFNNGESIPVFGLGTWKSKPGEVTQAVKDAIDIGYRH 240 R S+A + + P IP T +G+++P GLGT+ ++ +V+ A+ GY H Sbjct: 15 RVSEAVVSISEPLNPPRVTIPTQTLPSGDTLPALGLGTYALDDDQIADSVRAALSSGYTH 74 Query: 241 IDCAYVYGNEKEVGEAITSKIKEGVVTREDLFITSKLWNTFHRPDLVXGXLQETLDNLNV 420 ID A Y NE+ +GE + R+D+F+TSK+ + + + +L+ L Sbjct: 75 IDTAEGYHNEEAIGEVLAE------YDRDDVFLTSKVLAKNLGYESLIQSCEASLERLET 128 Query: 421 QYLDLYLIHWP 453 YLDLYLIHWP Sbjct: 129 DYLDLYLIHWP 139 >UniRef50_UPI0000D56CE5 Cluster: PREDICTED: similar to CG6084-PA, isoform A; n=1; Tribolium castaneum|Rep: PREDICTED: similar to CG6084-PA, isoform A - Tribolium castaneum Length = 493 Score = 81.4 bits (192), Expect = 3e-14 Identities = 59/158 (37%), Positives = 82/158 (51%) Frame = +1 Query: 118 IPVVTFNNGESIPVFGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITS 297 IP+ NNG IPVFGL + EV + V+ + YR +DC+ ++ NEK G A+ Sbjct: 8 IPIAKLNNGIEIPVFGLAAPQDF-FEV-ENVQLVVSSNYRLMDCS-IFENEKRFGVALQQ 64 Query: 298 KIKEGVVTREDLFITSKLWNTFHRPDLVXGXLQETLDNLNVQYLDLYLIHWPQAYKEDGS 477 I+ G + R+DLF+ SK T + +LV L +TL L V YLDLYLI P A K Sbjct: 65 LIEGGKIRRKDLFLMSKFCCT-NTTNLVKAALLDTLKKLQVAYLDLYLIERPPACK---- 119 Query: 478 LFPTXQSGKIQFSDXDYVDXWKAMEPLXKEGLVXSIGV 591 D + ++ W+AME L E L +IG+ Sbjct: 120 -------------DHNLIETWEAMEGLYSEKLTRAIGL 144 Score = 70.1 bits (164), Expect = 7e-11 Identities = 33/66 (50%), Positives = 44/66 (66%), Gaps = 1/66 (1%) Frame = +1 Query: 397 ETLDNLNVQYLDLYLIHWPQAYKEDGSLFP-TXQSGKIQFSDXDYVDXWKAMEPLXKEGL 573 E+L NL + YLD+YL+HWP A KE SL P ++G SD D+VD WKAME + ++ L Sbjct: 271 ESLKNLQLDYLDVYLMHWPHALKEGPSLHPIDPKTGLFIPSDVDFVDTWKAMEKMHEKDL 330 Query: 574 VXSIGV 591 SIG+ Sbjct: 331 TKSIGI 336 Score = 50.0 bits (114), Expect = 8e-05 Identities = 19/34 (55%), Positives = 27/34 (79%) Frame = +3 Query: 594 NFNSKQLERLLQXATVKPVVNQVECHPLPHQKXL 695 NFNSKQ+ER+L+ T++P VNQ++CHP +Q L Sbjct: 146 NFNSKQIERILENCTIRPQVNQIQCHPYLNQAKL 179 Score = 48.8 bits (111), Expect = 2e-04 Identities = 19/34 (55%), Positives = 26/34 (76%) Frame = +3 Query: 594 NFNSKQLERLLQXATVKPVVNQVECHPLPHQKXL 695 NFNS Q++RLL+ A + PV+NQ+ECHP +Q L Sbjct: 338 NFNSNQIDRLLKSAKIAPVINQIECHPYLNQSKL 371 >UniRef50_A6VNW9 Cluster: Aldo/keto reductase precursor; n=1; Actinobacillus succinogenes 130Z|Rep: Aldo/keto reductase precursor - Actinobacillus succinogenes 130Z Length = 315 Score = 81.4 bits (192), Expect = 3e-14 Identities = 40/129 (31%), Positives = 74/129 (57%) Frame = +1 Query: 67 LRSSQAAAKLINKMAPKIPVVTFNNGESIPVFGLGTWKSKPGEVTQAVKDAIDIGYRHID 246 ++++ +A ++ + K V NNG +P+ G+G W P + ++V +A+ GYR ID Sbjct: 25 IKAADSAGQIFHPFDFKKRTVKLNNGIEMPIIGIGVWTLTPEQTEKSVGEALKAGYRLID 84 Query: 247 CAYVYGNEKEVGEAITSKIKEGVVTREDLFITSKLWNTFHRPDLVXGXLQETLDNLNVQY 426 A +Y NE+ VG A +++ + RE++FIT+K++ + + + E L L+ Y Sbjct: 85 TARMYRNEQAVGRA----VRDSGIPREEIFITTKIYGSGDYAN-AEAAINERLRLLDTDY 139 Query: 427 LDLYLIHWP 453 +DL L+H+P Sbjct: 140 IDLLLLHYP 148 >UniRef50_Q8EVS8 Cluster: Oxidoreductase; n=1; Mycoplasma penetrans|Rep: Oxidoreductase - Mycoplasma penetrans Length = 289 Score = 81.0 bits (191), Expect = 4e-14 Identities = 45/112 (40%), Positives = 62/112 (55%) Frame = +1 Query: 118 IPVVTFNNGESIPVFGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITS 297 + ++T NNG IP G G ++ E VK AI IGYR ID A Y NEKE G Sbjct: 6 VKLITLNNGNKIPSIGFGVFQIPKEETADCVKKAISIGYRLIDTAQAYHNEKETGLG--- 62 Query: 298 KIKEGVVTREDLFITSKLWNTFHRPDLVXGXLQETLDNLNVQYLDLYLIHWP 453 IK V RE++F+T+K+W + + + + E+L L+ YLDL L+H P Sbjct: 63 -IKLSGVKREEIFLTTKVWVSNY--ERCYESVIESLKRLDTSYLDLILLHQP 111 >UniRef50_Q8EUH6 Cluster: Oxidoreductase; n=1; Mycoplasma penetrans|Rep: Oxidoreductase - Mycoplasma penetrans Length = 285 Score = 81.0 bits (191), Expect = 4e-14 Identities = 54/152 (35%), Positives = 78/152 (51%), Gaps = 1/152 (0%) Frame = +1 Query: 139 NGESIPVFGLGTWKSKPGEVTQAVKDAID-IGYRHIDCAYVYGNEKEVGEAITSKIKEGV 315 NG +P+ GLG +K++ + AID GYR ID A VY NE+ VG AI K+ Sbjct: 8 NGLHMPIIGLGVYKAEGENCENTIIKAIDDYGYRMIDTAQVYFNEEFVGNAI----KQTK 63 Query: 316 VTREDLFITSKLWNTFHRPDLVXGXLQETLDNLNVQYLDLYLIHWPQAYKEDGSLFPTXQ 495 + RED+FIT+K+W + + + + ++L L Y+DL L+H P Sbjct: 64 IKREDIFITTKVWISNYGYNNTMYSISKSLKKLQTNYIDLVLLHQPFG------------ 111 Query: 496 SGKIQFSDXDYVDXWKAMEPLXKEGLVXSIGV 591 DY WKA+E L K+G+V +IGV Sbjct: 112 ---------DYYSAWKALEVLYKKGIVKAIGV 134 >UniRef50_A3JU52 Cluster: 2,5-diketo-D-gluconic acid reductase A; n=1; Rhodobacterales bacterium HTCC2150|Rep: 2,5-diketo-D-gluconic acid reductase A - Rhodobacterales bacterium HTCC2150 Length = 334 Score = 81.0 bits (191), Expect = 4e-14 Identities = 51/136 (37%), Positives = 67/136 (49%), Gaps = 7/136 (5%) Frame = +1 Query: 67 LRSSQAAAKLINKMAPKIPVVTFNNGESIPVFGLGTWKSKPGEVTQAVKDAIDIGYRHID 246 L S+QA + M T N +IP G GT+ + + AI GYRHID Sbjct: 20 LASNQANNGTEHPMTNTATTFTLNTTTTIPAVGFGTYLISNDDAKSTISAAIQAGYRHID 79 Query: 247 CAYVYGNEKEVGEAITSKIKEGVVTREDLFITSKLW--NTF--HRPDLVXGXLQE---TL 405 A Y NEK VG I + ++ +TR+DLF+T+KLW N P L E +L Sbjct: 80 TASGYQNEKTVGAGIKAGLQSAGITRKDLFVTAKLWPGNPAWGDAPKTKAQTLDECDASL 139 Query: 406 DNLNVQYLDLYLIHWP 453 L + Y+DLYLIH P Sbjct: 140 ARLGLDYVDLYLIHAP 155 >UniRef50_A0L1A2 Cluster: Aldo/keto reductase; n=8; Gammaproteobacteria|Rep: Aldo/keto reductase - Shewanella sp. (strain ANA-3) Length = 280 Score = 81.0 bits (191), Expect = 4e-14 Identities = 41/102 (40%), Positives = 61/102 (59%) Frame = +1 Query: 148 SIPVFGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIKEGVVTRE 327 ++P+ G GT++ K AV A++ G RHID A +YGNE+ VG+AI + + RE Sbjct: 16 AMPMLGTGTFRLKDNAAFDAVLMALEEGSRHIDTAQIYGNEQAVGDAINT----SGIPRE 71 Query: 328 DLFITSKLWNTFHRPDLVXGXLQETLDNLNVQYLDLYLIHWP 453 +LFIT+K+W + + ++L L +YLDL LIHWP Sbjct: 72 ELFITTKVWTENLTKERFETSVIDSLTALQTKYLDLLLIHWP 113 >UniRef50_A7RRF6 Cluster: Predicted protein; n=2; Nematostella vectensis|Rep: Predicted protein - Nematostella vectensis Length = 275 Score = 81.0 bits (191), Expect = 4e-14 Identities = 43/108 (39%), Positives = 62/108 (57%) Frame = +1 Query: 130 TFNNGESIPVFGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIKE 309 T ++G IP FGLG + QAV A++ GYR ID A Y NEK VGEA ++E Sbjct: 8 TLSDGYKIPRFGLGLYDLDEKHTKQAVLWALENGYRMIDTAASYNNEKRVGEA----LRE 63 Query: 310 GVVTREDLFITSKLWNTFHRPDLVXGXLQETLDNLNVQYLDLYLIHWP 453 V R ++++ +K+++T H + +L L V Y+DLYLIH+P Sbjct: 64 SAVPRSEVYLVTKVYHTDHGYEKTMKAYDRSLSALGVDYVDLYLIHFP 111 Score = 35.1 bits (77), Expect = 2.5 Identities = 16/39 (41%), Positives = 21/39 (53%) Frame = +3 Query: 594 NFNSKQLERLLQXATVKPVVNQVECHPLPHQKXLXSSVR 710 NFN LE L + + + PVVNQ+E HP + L R Sbjct: 139 NFNIHHLEALQKHSVIPPVVNQIEVHPYLQMEELVDFCR 177 >UniRef50_Q5FK99 Cluster: Oxidoreductase aldo-keto reductase family; n=5; Lactobacillus|Rep: Oxidoreductase aldo-keto reductase family - Lactobacillus acidophilus Length = 289 Score = 80.6 bits (190), Expect = 5e-14 Identities = 56/159 (35%), Positives = 75/159 (47%), Gaps = 1/159 (0%) Frame = +1 Query: 118 IPVVTFNNGESIPVFGLGTWK-SKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAIT 294 IP + N+G IP G G ++ S E +AV+ AI GYR ID A Y N+ VGEAI Sbjct: 4 IPKIKLNDGNEIPQLGFGVFQISNHDEAVKAVESAISNGYRLIDTAEAYNNQTAVGEAI- 62 Query: 295 SKIKEGVVTREDLFITSKLWNTFHRPDLVXGXLQETLDNLNVQYLDLYLIHWPQAYKEDG 474 K V R+D+F+T+KLW + + + E L L Y+D+ L+H QAY Sbjct: 63 ---KNSDVNRDDIFLTTKLWVSNFTYEKASKAIDEDLKELGTDYIDMMLLH--QAY---- 113 Query: 475 SLFPTXQSGKIQFSDXDYVDXWKAMEPLXKEGLVXSIGV 591 D W+A+E K G SIGV Sbjct: 114 ---------------GDVAGAWRALEDAQKAGKTKSIGV 137 >UniRef50_Q1M4Z6 Cluster: Putative aldo-keto reductase/oxidase; n=1; Rhizobium leguminosarum bv. viciae 3841|Rep: Putative aldo-keto reductase/oxidase - Rhizobium leguminosarum bv. viciae (strain 3841) Length = 274 Score = 80.2 bits (189), Expect = 7e-14 Identities = 41/106 (38%), Positives = 59/106 (55%) Frame = +1 Query: 151 IPVFGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIKEGVVTRED 330 IP G GTW E Q V A++ G RHID A YGNE++V IK+ V R + Sbjct: 10 IPQMGYGTWNRSADEAHQGVIWALEAGCRHIDTAQGYGNEQDVARG----IKDAGVARNE 65 Query: 331 LFITSKLWNTFHRPDLVXGXLQETLDNLNVQYLDLYLIHWPQAYKE 468 +FIT+K+ + P V ++E+L+ L V +DL L+HWP + + Sbjct: 66 IFITTKVKPDNYGPGAVMPSVRESLEKLRVDQVDLLLLHWPSPHNK 111 >UniRef50_Q54NR2 Cluster: Aldo-keto reductase; n=3; Dictyostelium discoideum AX4|Rep: Aldo-keto reductase - Dictyostelium discoideum AX4 Length = 305 Score = 79.8 bits (188), Expect = 9e-14 Identities = 52/157 (33%), Positives = 79/157 (50%), Gaps = 6/157 (3%) Frame = +1 Query: 139 NGESIPVFGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKI--KEG 312 N +P+ G+GT+K ++ +K ++ GYR ID A +Y NE+ +G+ + + +G Sbjct: 23 NPIKMPMLGIGTFKLN--DIENIIKVGLENGYRRIDTASMYNNEERIGKVLNEMVTKNDG 80 Query: 313 V----VTREDLFITSKLWNTFHRPDLVXGXLQETLDNLNVQYLDLYLIHWPQAYKEDGSL 480 + + REDLFITSK + + +L L + YLD YLIHWP DGS Sbjct: 81 LDGKKIKREDLFITSKCSFMEQGYENALKAFESSLKKLQLDYLDCYLIHWPGVKGLDGS- 139 Query: 481 FPTXQSGKIQFSDXDYVDXWKAMEPLXKEGLVXSIGV 591 SG + W+A+E L ++ V SIGV Sbjct: 140 ----DSG----NSIQRAQTWRALEKLYQDKKVRSIGV 168 >UniRef50_Q6CEJ0 Cluster: Yarrowia lipolytica chromosome B of strain CLIB122 of Yarrowia lipolytica; n=1; Yarrowia lipolytica|Rep: Yarrowia lipolytica chromosome B of strain CLIB122 of Yarrowia lipolytica - Yarrowia lipolytica (Candida lipolytica) Length = 302 Score = 79.8 bits (188), Expect = 9e-14 Identities = 59/166 (35%), Positives = 79/166 (47%), Gaps = 8/166 (4%) Frame = +1 Query: 118 IPVVTFNNGESIPVFGLGT---WKSKPGE-----VTQAVKDAIDIGYRHIDCAYVYGNEK 273 +P V +NG IP G G+ WK PGE + AV AI+ G+ HID A YG EK Sbjct: 3 VPKVKLSNGLEIPAIGFGSGTKWKRPPGEKEERELIDAVVSAINAGHLHIDTAEFYGTEK 62 Query: 274 EVGEAITSKIKEGVVTREDLFITSKLWNTFHRPDLVXGXLQETLDNLNVQYLDLYLIHWP 453 ++GEA IKE V R+D+F+TSK D + + L L Y DL+LIH P Sbjct: 63 QIGEA----IKESGVPRKDIFLTSKTLFGLLADDPIES-ISNQLKTLQTDYFDLFLIHVP 117 Query: 454 QAYKEDGSLFPTXQSGKIQFSDXDYVDXWKAMEPLXKEGLVXSIGV 591 +D + D W +E L ++GL +IGV Sbjct: 118 P--NDD--------------INYDLAKAWGVLEQLYEKGLAKAIGV 147 Score = 33.5 bits (73), Expect = 7.8 Identities = 13/28 (46%), Positives = 20/28 (71%) Frame = +3 Query: 594 NFNSKQLERLLQXATVKPVVNQVECHPL 677 N + +LE +++ A +KP VNQ+E HPL Sbjct: 149 NHSPAELETIIKVAKIKPHVNQIEFHPL 176 >UniRef50_Q4WUF7 Cluster: Aldo-keto reductase, putative; n=3; Pezizomycotina|Rep: Aldo-keto reductase, putative - Aspergillus fumigatus (Sartorya fumigata) Length = 283 Score = 79.8 bits (188), Expect = 9e-14 Identities = 53/154 (34%), Positives = 83/154 (53%), Gaps = 2/154 (1%) Frame = +1 Query: 136 NNGESIPVFGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIKEGV 315 N+ IP G G ++S G+ Q+ A++ GYRHID A YGNEKEVGEA +++ Sbjct: 15 NSDVKIPRLGFGVYRSPTGQCVQSSLRALEAGYRHIDTAQFYGNEKEVGEA----LRKCG 70 Query: 316 VTREDLFITSKLWNTFHRPDLVXGXLQETLDNLNVQ--YLDLYLIHWPQAYKEDGSLFPT 489 + R D+F+T+K+ + P+ L E+++ + + Y+DL+LIH GS Sbjct: 71 IPRSDVFVTTKILSPAGSPEATYQKLLESVEKIGGRDGYVDLFLIH----SSSSGS---- 122 Query: 490 XQSGKIQFSDXDYVDXWKAMEPLXKEGLVXSIGV 591 +G+ + W+A+E L +EG SIGV Sbjct: 123 --AGR--------KELWQALERLLEEGKTRSIGV 146 >UniRef50_Q4WP69 Cluster: Aldehyde reductase, putative; n=1; Aspergillus fumigatus|Rep: Aldehyde reductase, putative - Aspergillus fumigatus (Sartorya fumigata) Length = 350 Score = 79.4 bits (187), Expect = 1e-13 Identities = 52/128 (40%), Positives = 65/128 (50%), Gaps = 6/128 (4%) Frame = +1 Query: 226 IGYRHIDCAYVYGNEKEVGEAITSKIKEGVVTREDLFITSKLWNTFHRPDLVXGXLQETL 405 +GYRHID A V NE EVG K+ V RE +F+TSKLWNT H P V L +T+ Sbjct: 72 VGYRHIDSAAVGLNEAEVGRGW----KKLGVPREGIFLTSKLWNTHHHPSHVEEALDKTV 127 Query: 406 DNLNVQYLDLYLI----HWPQAYKEDGSLFPTXQSGKIQFS--DXDYVDXWKAMEPLXKE 567 +L YLDLYL+ H Y+ P + G +F D D W A E L Sbjct: 128 KDLQTNYLDLYLLYPLGHILHTYQRH---IPASRPGHKRFRLVDIPIGDTWAAREKLVNA 184 Query: 568 GLVXSIGV 591 G + S+GV Sbjct: 185 GKIRSLGV 192 >UniRef50_A5BF24 Cluster: Putative uncharacterized protein; n=1; Vitis vinifera|Rep: Putative uncharacterized protein - Vitis vinifera (Grape) Length = 212 Score = 79.0 bits (186), Expect = 2e-13 Identities = 55/156 (35%), Positives = 79/156 (50%), Gaps = 4/156 (2%) Frame = +1 Query: 136 NNGESIPVFGLGT--WKSKPGE-VTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIK 306 + G++IP+ G+ T + P E + ++ AI++GYRH DC Y +EK +GEAI +K Sbjct: 5 STGKAIPLVGMVTTVYPFAPSETMIDSILTAIELGYRHFDCVAAYLSEKPLGEAIKKAVK 64 Query: 307 EGVV-TREDLFITSKLWNTFHRPDLVXGXLQETLDNLNVQYLDLYLIHWPQAYKEDGSLF 483 G++ +R++LFIT LQ NL + YLDLYLIHW + K Sbjct: 65 LGLIKSRDELFIT----------------LQAL--NLQLDYLDLYLIHWSVSLKPGNYEL 106 Query: 484 PTXQSGKIQFSDXDYVDXWKAMEPLXKEGLVXSIGV 591 P + + D WKAME K L +IGV Sbjct: 107 PVNKDDHLPI---DLGSVWKAMEDFQKLSLTKAIGV 139 >UniRef50_Q4DJ59 Cluster: Aldo/keto reductase, putative; n=2; Trypanosoma|Rep: Aldo/keto reductase, putative - Trypanosoma cruzi Length = 322 Score = 79.0 bits (186), Expect = 2e-13 Identities = 53/159 (33%), Positives = 79/159 (49%), Gaps = 1/159 (0%) Frame = +1 Query: 118 IPVVTFNNGESIPVFGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITS 297 +P++ + G IP G+GT++ E AV A+ +G+R +D A Y NE+ VG A Sbjct: 15 LPLLESSGGMRIPHMGVGTYELYGDESRIAVLAALRLGFRLVDTAAGYHNEEHVGAA--- 71 Query: 298 KIKEGVVTREDLFITSKLW-NTFHRPDLVXGXLQETLDNLNVQYLDLYLIHWPQAYKEDG 474 I+E V RE+LF+ K+ +LV ++E++ L + Y D LIHWP G Sbjct: 72 -IEESGVQREELFVVVKIAPKAMASEELVEKGIRESVRKLRIAYADCVLIHWPGC----G 126 Query: 475 SLFPTXQSGKIQFSDXDYVDXWKAMEPLXKEGLVXSIGV 591 L P G WK M+ L KEG++ +GV Sbjct: 127 GLKPEEAEGHRAARHR----CWKVMQALKKEGIIRHLGV 161 >UniRef50_P15339 Cluster: 2,5-diketo-D-gluconic acid reductase B; n=6; Actinomycetales|Rep: 2,5-diketo-D-gluconic acid reductase B - Corynebacterium sp. (strain SHS752001) Length = 277 Score = 78.6 bits (185), Expect = 2e-13 Identities = 53/160 (33%), Positives = 75/160 (46%) Frame = +1 Query: 112 PKIPVVTFNNGESIPVFGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAI 291 P IP ++ N+G GLGT+ + E A+ AID GYR +D A Y NE EVG A Sbjct: 2 PNIPTISLNDGRPFAEPGLGTYNLRGDEGVAAMVAAIDSGYRLLDTAVNYENESEVGRA- 60 Query: 292 TSKIKEGVVTREDLFITSKLWNTFHRPDLVXGXLQETLDNLNVQYLDLYLIHWPQAYKED 471 ++ V R++L + SK+ H ++ +LD L + +DL LIHWP Sbjct: 61 ---VRASSVDRDELIVASKIPGRQHGRAEAVDSIRGSLDRLGLDVIDLQLIHWPNP---- 113 Query: 472 GSLFPTXQSGKIQFSDXDYVDXWKAMEPLXKEGLVXSIGV 591 S ++D W+ M + GLV SIGV Sbjct: 114 --------------SVGRWLDTWRGMIDAREAGLVRSIGV 139 >UniRef50_A7BES9 Cluster: Putative uncharacterized protein; n=1; Actinomyces odontolyticus ATCC 17982|Rep: Putative uncharacterized protein - Actinomyces odontolyticus ATCC 17982 Length = 282 Score = 78.2 bits (184), Expect = 3e-13 Identities = 41/109 (37%), Positives = 62/109 (56%) Frame = +1 Query: 127 VTFNNGESIPVFGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIK 306 +T NNG +IP GLGT+ +P + AV A+D Y ID A VY NE+ VG + + K Sbjct: 4 ITLNNGITIPQVGLGTYLLEPDDAQSAVTYALDNDYTLIDTANVYVNERAVGRGMRASSK 63 Query: 307 EGVVTREDLFITSKLWNTFHRPDLVXGXLQETLDNLNVQYLDLYLIHWP 453 R+++F+ +KLW +F ++ETL+ L Y+DL ++H P Sbjct: 64 ----ARDEIFLETKLWPSFFER---ASAVEETLERLGTDYIDLMILHQP 105 Score = 37.1 bits (82), Expect = 0.63 Identities = 16/39 (41%), Positives = 23/39 (58%) Frame = +3 Query: 594 NFNSKQLERLLQXATVKPVVNQVECHPLPHQKXLXSSVR 710 NF+ Q +R+L V P +NQVECHP Q L + ++ Sbjct: 132 NFDVAQTQRILDECEVVPTINQVECHPYFPQTELKALLK 170 >UniRef50_Q5K8C5 Cluster: Aldo-keto reductase, putative; n=1; Filobasidiella neoformans|Rep: Aldo-keto reductase, putative - Cryptococcus neoformans (Filobasidiella neoformans) Length = 303 Score = 78.2 bits (184), Expect = 3e-13 Identities = 41/104 (39%), Positives = 60/104 (57%) Frame = +1 Query: 136 NNGESIPVFGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIKEGV 315 ++G +IP FGLG ++ E VK A++ GYRH+D A Y NE G+AI +K Sbjct: 36 HDGNAIPQFGLGVYEMNDKETYDCVKWALEAGYRHVDTAEWYENEAPCGKAIADFLKATG 95 Query: 316 VTREDLFITSKLWNTFHRPDLVXGXLQETLDNLNVQYLDLYLIH 447 +RE++F+TSKL N + L+ +L V+Y DLYL+H Sbjct: 96 TSREEIFLTSKLKNN-SSYEQAFVDLKGSLKRSGVEYFDLYLMH 138 >UniRef50_Q5UYI9 Cluster: Oxidoreductase; n=1; Haloarcula marismortui|Rep: Oxidoreductase - Haloarcula marismortui (Halobacterium marismortui) Length = 264 Score = 77.8 bits (183), Expect = 4e-13 Identities = 38/97 (39%), Positives = 55/97 (56%) Frame = +1 Query: 163 GLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIKEGVVTREDLFIT 342 G+GTW V ++V+ +++GY H+D A Y NE E+GEA+ RED+F+T Sbjct: 3 GVGTWDIDGDTVQKSVRAGLNVGYAHVDTAEGYKNESEIGEALAD------YDREDVFLT 56 Query: 343 SKLWNTFHRPDLVXGXLQETLDNLNVQYLDLYLIHWP 453 SK+ + V + +LD L YLDLYL+HWP Sbjct: 57 SKVLPKHLDYESVIEACEASLDRLGTDYLDLYLVHWP 93 >UniRef50_Q5B5R6 Cluster: Putative uncharacterized protein; n=1; Emericella nidulans|Rep: Putative uncharacterized protein - Emericella nidulans (Aspergillus nidulans) Length = 682 Score = 76.6 bits (180), Expect = 8e-13 Identities = 48/125 (38%), Positives = 70/125 (56%), Gaps = 3/125 (2%) Frame = +1 Query: 136 NNGESIPVFGLGTWKS-KPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIKEG 312 N G IP GLGT ++ KPG V +AV+ A+ GYRHID A G E E+G+A +K+ Sbjct: 417 NTGALIPAVGLGTRRAQKPGLVYRAVRSALKTGYRHIDTAMSSGVEHEIGQA----VKDS 472 Query: 313 VVTREDLFITSKLWNTFHRPDLVXGXLQETLDNLNVQYLDLYLI--HWPQAYKEDGSLFP 486 V+R +++T+KL N +H V L +L L + Y+DLYL+ W G +F Sbjct: 473 GVSRSQVWVTTKLDNRWH--TRVQEALDMSLSELGMDYVDLYLMLADWDFVKTWYGKIFL 530 Query: 487 TXQSG 501 + +G Sbjct: 531 SLMAG 535 >UniRef50_A7D761 Cluster: Aldo/keto reductase; n=2; Halobacteriaceae|Rep: Aldo/keto reductase - Halorubrum lacusprofundi ATCC 49239 Length = 665 Score = 76.6 bits (180), Expect = 8e-13 Identities = 45/165 (27%), Positives = 73/165 (44%), Gaps = 18/165 (10%) Frame = +1 Query: 151 IPVFGLGTWKSKPGEVTQAVKD---AIDIGYRHIDCAYVYGNEKEVGEAITSKIKEGVVT 321 +P G G + + GE V A+D GYR +D A +YGNE +GE + + G Sbjct: 376 LPAVGFGCSRYRDGEYVDRVDSIATALDAGYRLLDSAELYGNEHRIGELLAAP---GAPD 432 Query: 322 REDLFITSKLWNTFHRPDLVXGXLQETLDNLNVQYLDLYLIHWPQAYKEDGSL------- 480 RE +F+ K W T HR + + + + L + D Y +HWP A + G L Sbjct: 433 RERVFLLGKAWRTNHRREHLLAACAGSREELGIDAFDCYALHWPSALEHRGELNRLAEKP 492 Query: 481 --------FPTXQSGKIQFSDXDYVDXWKAMEPLXKEGLVXSIGV 591 FP + G+ +D W+ +E + + G ++G+ Sbjct: 493 VERQETLTFPEGEDGEPATADVALATAWRNLEAVHERGWARTLGI 537 >UniRef50_Q6U5V3 Cluster: Putative uncharacterized protein; n=1; Klebsiella pneumoniae|Rep: Putative uncharacterized protein - Klebsiella pneumoniae Length = 279 Score = 76.2 bits (179), Expect = 1e-12 Identities = 53/155 (34%), Positives = 71/155 (45%) Frame = +1 Query: 127 VTFNNGESIPVFGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIK 306 + N+G +P G G W +V ++ A+ G+RH D A Y NE VG A ++ Sbjct: 6 ILLNDGYYMPRPGCGLWLIDNRDVDSLIRQALKAGFRHFDTAQAYFNEDGVGRA----LR 61 Query: 307 EGVVTREDLFITSKLWNTFHRPDLVXGXLQETLDNLNVQYLDLYLIHWPQAYKEDGSLFP 486 V RE LFITSK+ ETL+ L V+YL+L+LIHWP K Sbjct: 62 YTEVPREQLFITSKIRGRDMGYARTLVSFNETLERLGVEYLELFLIHWPIPAKN------ 115 Query: 487 TXQSGKIQFSDXDYVDXWKAMEPLXKEGLVXSIGV 591 YV+ W+A L GL+ SIGV Sbjct: 116 ------------LYVETWEASIELEASGLIRSIGV 138 Score = 33.5 bits (73), Expect = 7.8 Identities = 13/27 (48%), Positives = 18/27 (66%) Frame = +3 Query: 594 NFNSKQLERLLQXATVKPVVNQVECHP 674 NF + +ERL++ V P VNQ+E HP Sbjct: 140 NFTCQHIERLIEDTGVVPAVNQLELHP 166 >UniRef50_Q6WGK4 Cluster: Aldose reductase; n=1; Pristionchus pacificus|Rep: Aldose reductase - Pristionchus pacificus Length = 293 Score = 76.2 bits (179), Expect = 1e-12 Identities = 47/150 (31%), Positives = 76/150 (50%), Gaps = 1/150 (0%) Frame = +1 Query: 145 ESIPVFGLGTWKSKPGEV-TQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIKEGVVT 321 + +P+ G+GT++ + V T + +A +GYR ID A +Y NE +G + +++ + Sbjct: 14 DRMPMIGVGTYQVQSQSVLTDTIDEAFRLGYRFIDTAQIYRNEAILGRILPDLLEKHSLK 73 Query: 322 REDLFITSKLWNTFHRPDLVXGXLQETLDNLNVQYLDLYLIHWPQAYKEDGSLFPTXQSG 501 RED+FITSK+ + ++L +L Y+DL LIHWP S + Sbjct: 74 REDIFITSKVSPINQGKGKTSKSVLKSLTDLQTPYIDLVLIHWPGT-----SRLKSNHKD 128 Query: 502 KIQFSDXDYVDXWKAMEPLXKEGLVXSIGV 591 +F YV+ +E L EG + SIGV Sbjct: 129 NAKFRAETYVE----LETLMDEGKIRSIGV 154 Score = 34.3 bits (75), Expect = 4.4 Identities = 13/27 (48%), Positives = 16/27 (59%) Frame = +3 Query: 594 NFNSKQLERLLQXATVKPVVNQVECHP 674 N+ K LE LL + P +NQ ECHP Sbjct: 156 NYEIKHLETLLAECRILPAINQCECHP 182 >UniRef50_Q9C1X5 Cluster: Xylose and arabinose reductase; n=1; Schizosaccharomyces pombe|Rep: Xylose and arabinose reductase - Schizosaccharomyces pombe (Fission yeast) Length = 283 Score = 76.2 bits (179), Expect = 1e-12 Identities = 55/155 (35%), Positives = 72/155 (46%) Frame = +1 Query: 127 VTFNNGESIPVFGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIK 306 VT NG IP G G + K E V A+D GYRHID A VYGNE G+AI + Sbjct: 11 VTLTNGMVIPRIGFGAFMLKYNECYGLVTQALDSGYRHIDTAAVYGNEDICGKAIVDWCE 70 Query: 307 EGVVTREDLFITSKLWNTFHRPDLVXGXLQETLDNLNVQYLDLYLIHWPQAYKEDGSLFP 486 + V R D+F+TSKL N ++ +L +L Y+DL+LI P K+ Sbjct: 71 KNNVKRTDIFLTSKLANCSDYYS-TRAAIRSSLHHLGT-YIDLFLIQSPAGGKK------ 122 Query: 487 TXQSGKIQFSDXDYVDXWKAMEPLXKEGLVXSIGV 591 + WKAME G + S+GV Sbjct: 123 ------------SRIASWKAMEEFVDSGDIRSVGV 145 >UniRef50_A6SI80 Cluster: Putative uncharacterized protein; n=1; Botryotinia fuckeliana B05.10|Rep: Putative uncharacterized protein - Botryotinia fuckeliana B05.10 Length = 253 Score = 76.2 bits (179), Expect = 1e-12 Identities = 53/164 (32%), Positives = 73/164 (44%), Gaps = 7/164 (4%) Frame = +1 Query: 121 PVVTFNNGESIPVFGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSK 300 P + N+G +P G G WK V +AI GYR D A Sbjct: 4 PTLKLNSGHEMPQVGFGLWKVDNATCADTVYNAIKTGYRLFDGAC--------------- 48 Query: 301 IKEGVVTREDLFITSKLWNTFHRPDLVXGXLQETLDNLNVQYLDLYLIHWPQA--YKEDG 474 DLFI SKLWN+FH D V ++ L + + Y DL+++H+P A Y + Sbjct: 49 ---------DLFIVSKLWNSFHDGDRVGPITRKQLADWGIDYFDLFIVHFPVALRYVDPA 99 Query: 475 SLFP-----TXQSGKIQFSDXDYVDXWKAMEPLXKEGLVXSIGV 591 +P + + G +Q S + W+AME L EGL SIGV Sbjct: 100 VRYPPGWQYSDKEGDVQQSKASIQETWQAMEKLVDEGLAKSIGV 143 >UniRef50_Q5V6N9 Cluster: Alcohol dehydrogenase; n=2; Halobacteriaceae|Rep: Alcohol dehydrogenase - Haloarcula marismortui (Halobacterium marismortui) Length = 667 Score = 76.2 bits (179), Expect = 1e-12 Identities = 46/165 (27%), Positives = 73/165 (44%), Gaps = 18/165 (10%) Frame = +1 Query: 151 IPVFGLGTWKSKPG---EVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIKEGVVT 321 +P G G + + G + ++ A+D GYR +D A +YGNE +G + + G Sbjct: 378 LPAIGFGCSRYRDGTYIDRADSIAAALDAGYRLLDSAELYGNEHRIGRILAAP---GAPD 434 Query: 322 REDLFITSKLWNTFHRPDLVXGXLQETLDNLNVQYLDLYLIHWPQAYKEDGSL------- 480 R +FI K+W T HR + + +LD L + D Y +HWP+A GSL Sbjct: 435 RRRVFILGKVWRTNHRRKHMLTACRSSLDELGIDAFDCYALHWPEALAHRGSLTRLAEKS 494 Query: 481 --------FPTXQSGKIQFSDXDYVDXWKAMEPLXKEGLVXSIGV 591 FP G I+ W+ +E L + G ++G+ Sbjct: 495 VARQEALTFPKNDRGDIETDSVSLQRAWENLEALHERGWTRTLGL 539 >UniRef50_Q3CZS2 Cluster: Oxidoreductase, aldo/keto reductase family; n=2; Streptococcus agalactiae|Rep: Oxidoreductase, aldo/keto reductase family - Streptococcus agalactiae H36B Length = 245 Score = 74.9 bits (176), Expect = 3e-12 Identities = 41/107 (38%), Positives = 59/107 (55%), Gaps = 1/107 (0%) Frame = +1 Query: 136 NNGESIPVFGLGTWK-SKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIKEG 312 NNG IP G G ++ P E Q+V DA+ +GYR ID A Y NE+ VG AI K+ Sbjct: 10 NNGVKIPSLGFGVFQIDDPLECEQSVLDALQVGYRLIDTASGYLNEEAVGRAI----KKS 65 Query: 313 VVTREDLFITSKLWNTFHRPDLVXGXLQETLDNLNVQYLDLYLIHWP 453 + R+++F+ +KLW + + L L + Y++LYLIH P Sbjct: 66 GIPRKEIFVVTKLWIQDASEEKAGPAIDRALKRLQLDYINLYLIHQP 112 >UniRef50_Q9HM42 Cluster: Alcohol dehydrogenase related protein; n=1; Thermoplasma acidophilum|Rep: Alcohol dehydrogenase related protein - Thermoplasma acidophilum Length = 284 Score = 74.9 bits (176), Expect = 3e-12 Identities = 41/106 (38%), Positives = 56/106 (52%), Gaps = 2/106 (1%) Frame = +1 Query: 142 GESIPVFGLGTW--KSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIKEGV 315 G + V G+GTW + E ++++ A+D G ID A +YG E VGEAI Sbjct: 13 GRKVSVIGVGTWSLEGSRSENVRSIRYALDHGVNFIDTAEMYGTEDIVGEAIKG------ 66 Query: 316 VTREDLFITSKLWNTFHRPDLVXGXLQETLDNLNVQYLDLYLIHWP 453 REDLFI +K+W T V +E+L L Y+DLY +HWP Sbjct: 67 YRREDLFIATKVWPTHFAYHDVLKSCEESLKKLGTDYVDLYQLHWP 112 >UniRef50_Q1DLF1 Cluster: Putative uncharacterized protein; n=1; Coccidioides immitis|Rep: Putative uncharacterized protein - Coccidioides immitis Length = 324 Score = 74.5 bits (175), Expect = 3e-12 Identities = 60/163 (36%), Positives = 80/163 (49%), Gaps = 11/163 (6%) Frame = +1 Query: 136 NNGESIPVFGLGTWKSKP-----GEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSK 300 N IP GLGT++ P G V +V A+ IGYRHID A YG V I + Sbjct: 11 NTSIRIPARGLGTFQVDPSLYPEGSVKDSVLHALKIGYRHIDAALAYG-WGSVERGIGAA 69 Query: 301 IKEGVVTREDLFITSKLWNTFHRPDLVXGXLQETLDNLNVQYLDLYLIHWPQAYKEDGSL 480 I+ V RED+F+ +KL N FH P+ V + +L NL + Y+ P AY + G Sbjct: 70 IRASGVPREDVFVVTKLHNCFHAPEDVEVGMNMSLKNLGLGYV-------PYAYTK-GEN 121 Query: 481 FPTXQ--SGK----IQFSDXDYVDXWKAMEPLXKEGLVXSIGV 591 + T + GK I+ S + WKAME L +G IGV Sbjct: 122 YSTVRKPDGKPVVDIELS-RAFDTTWKAMENLVDQGKAKLIGV 163 Score = 35.5 bits (78), Expect = 1.9 Identities = 17/34 (50%), Positives = 23/34 (67%) Frame = +3 Query: 594 NFNSKQLERLLQXATVKPVVNQVECHPLPHQKXL 695 NF++ +L+RLL + PVVNQVE +P QK L Sbjct: 165 NFSTPKLKRLLSVCRIFPVVNQVELNPYFPQKQL 198 >UniRef50_A7SGW6 Cluster: Predicted protein; n=1; Nematostella vectensis|Rep: Predicted protein - Nematostella vectensis Length = 264 Score = 74.1 bits (174), Expect = 4e-12 Identities = 41/110 (37%), Positives = 65/110 (59%) Frame = +1 Query: 127 VTFNNGESIPVFGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIK 306 VT N+G +P+FGLG ++ + G A+ GYR +D A +Y NEKEVG A+ K Sbjct: 13 VTLNDGRKMPLFGLGVFRLETG-CEDVCLFALKNGYRMLDTADIYQNEKEVGSAVR---K 68 Query: 307 EGVVTREDLFITSKLWNTFHRPDLVXGXLQETLDNLNVQYLDLYLIHWPQ 456 G + RED+++T+KL + +E++ L++ Y+DL+LIH P+ Sbjct: 69 SG-LKREDIYVTTKLKPSEEGHSNALKYAKESIKKLDIGYVDLFLIHTPR 117 >UniRef50_Q0CK00 Cluster: Predicted protein; n=1; Aspergillus terreus NIH2624|Rep: Predicted protein - Aspergillus terreus (strain NIH 2624) Length = 292 Score = 74.1 bits (174), Expect = 4e-12 Identities = 45/122 (36%), Positives = 68/122 (55%), Gaps = 9/122 (7%) Frame = +1 Query: 115 KIPVVTFNNGESIPVFGLGT----WKSKPGEVT-----QAVKDAIDIGYRHIDCAYVYGN 267 K P ++ +G +P+ G GT +K P + T + +K A++ G+ HID A YG Sbjct: 2 KWPALSLKDGNLVPILGFGTGTAWYKDDPNDPTNPELIEVLKAALEKGFHHIDAADSYGT 61 Query: 268 EKEVGEAITSKIKEGVVTREDLFITSKLWNTFHRPDLVXGXLQETLDNLNVQYLDLYLIH 447 E+EVG A I+E + RE LFIT+K+ + V G L +L+ L + Y+DLYL+H Sbjct: 62 EREVGIA----IRESGIPREQLFITTKVLEGWKD---VPGALDASLERLQLDYVDLYLLH 114 Query: 448 WP 453 P Sbjct: 115 NP 116 Score = 33.5 bits (73), Expect = 7.8 Identities = 23/83 (27%), Positives = 32/83 (38%), Gaps = 3/83 (3%) Frame = +3 Query: 435 VPDTLAPGLQGRRLSLPDRXIR*NPVXXXXXXXXX---EGYGAAXQRGSGXEHRSPNFNS 605 VP L L+ +L D + NP +G A G NF Sbjct: 92 VPGALDASLERLQLDYVDLYLLHNPYVIPNLTDIQSAWKGLEAVKATGKARSIGVSNFQR 151 Query: 606 KQLERLLQXATVKPVVNQVECHP 674 LE +L+ +V P +NQ+E HP Sbjct: 152 NHLEAILETCSVVPAINQLEYHP 174 Database: uniref50 Posted date: Oct 5, 2007 11:19 AM Number of letters in database: 575,637,011 Number of sequences in database: 1,657,284 Lambda K H 0.318 0.134 0.401 Gapped Lambda K H 0.279 0.0580 0.190 Matrix: BLOSUM62 Gap Penalties: Existence: 9, Extension: 2 Number of Hits to DB: 761,931,624 Number of Sequences: 1657284 Number of extensions: 14983226 Number of successful extensions: 58830 Number of sequences better than 10.0: 468 Number of HSP's better than 10.0 without gapping: 47125 Number of HSP's successfully gapped in prelim test: 0 Number of HSP's that attempted gapping in prelim test: 0 Number of HSP's gapped (non-prelim): 57026 length of database: 575,637,011 effective HSP length: 100 effective length of database: 409,908,611 effective search space used: 84441173866 frameshift window, decay const: 40, 0.1 T: 12 A: 40 X1: 16 ( 7.3 bits) X2: 37 (14.9 bits) X3: 62 (25.0 bits) S1: 41 (21.7 bits)
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