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Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= MFBP01_F_E17
         (924 letters)

Database: uniref50 
           1,657,284 sequences; 575,637,011 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

UniRef50_UPI000051A39F Cluster: PREDICTED: similar to Fumarylace...   263   5e-69
UniRef50_P35505 Cluster: Fumarylacetoacetase; n=108; cellular or...   232   8e-60
UniRef50_P16930 Cluster: Fumarylacetoacetase; n=33; cellular org...   225   9e-58
UniRef50_Q3DXY2 Cluster: Fumarylacetoacetase; n=1; Chloroflexus ...   186   5e-46
UniRef50_O65374 Cluster: F12F1.8 protein; n=7; Eukaryota|Rep: F1...   177   2e-43
UniRef50_Q46UA3 Cluster: Fumarylacetoacetase; n=3; Proteobacteri...   169   9e-41
UniRef50_Q00770 Cluster: Fumarylacetoacetase; n=15; Pezizomycoti...   167   3e-40
UniRef50_A0BKF7 Cluster: Chromosome undetermined scaffold_112, w...   156   9e-37
UniRef50_A7ENI0 Cluster: Putative uncharacterized protein; n=1; ...   148   2e-34
UniRef50_Q4PEP0 Cluster: Putative uncharacterized protein; n=1; ...   132   9e-30
UniRef50_Q6EMI8 Cluster: Fumarylacetoacetase; n=16; Proteobacter...   131   2e-29
UniRef50_UPI00005A0527 Cluster: PREDICTED: similar to Fumarylace...   126   1e-27
UniRef50_A1SEE6 Cluster: Fumarylacetoacetase; n=10; Actinomyceta...   125   2e-27
UniRef50_A6VYW9 Cluster: Fumarylacetoacetase; n=2; Proteobacteri...   120   5e-26
UniRef50_Q2UHQ1 Cluster: RIB40 genomic DNA, SC023; n=1; Aspergil...   113   8e-24
UniRef50_Q7W190 Cluster: Fumarylacetoacetase; n=9; Proteobacteri...   108   2e-22
UniRef50_Q4P904 Cluster: Putative uncharacterized protein; n=1; ...   108   2e-22
UniRef50_Q39M11 Cluster: Fumarylacetoacetase; n=17; Bacteria|Rep...   100   5e-20
UniRef50_Q13R26 Cluster: Fumarylacetoacetase; n=1; Burkholderia ...   100   6e-20
UniRef50_A4QQB2 Cluster: Putative uncharacterized protein; n=3; ...    82   2e-14
UniRef50_A2QIN6 Cluster: Remark: Hereditary tyrosinemia type 1; ...    81   5e-14
UniRef50_A1DCJ6 Cluster: Fumarylacetoacetate hydrolase; n=3; Tri...    81   5e-14
UniRef50_Q0V4X9 Cluster: Putative uncharacterized protein; n=1; ...    73   1e-11
UniRef50_A2QEA7 Cluster: Catalytic activity: 4-fumarylacetoaceta...    70   7e-11
UniRef50_Q2HI94 Cluster: Putative uncharacterized protein; n=1; ...    64   5e-09
UniRef50_UPI00003B90DC Cluster: UPI00003B90DC related cluster; n...    58   3e-07
UniRef50_Q5P7D0 Cluster: General (Type II) secretion pathway (GS...    38   0.36 
UniRef50_A7S2R3 Cluster: Predicted protein; n=1; Nematostella ve...    36   1.5  
UniRef50_Q0CBB3 Cluster: Predicted protein; n=1; Aspergillus ter...    35   3.4  
UniRef50_Q21YQ2 Cluster: Type III restriction enzyme, res subuni...    34   5.9  
UniRef50_Q00UW0 Cluster: Homology to unknown gene; n=2; Ostreoco...    34   5.9  
UniRef50_A7RT37 Cluster: Predicted protein; n=1; Nematostella ve...    34   5.9  
UniRef50_O96216 Cluster: Putative uncharacterized protein PFB061...    33   7.8  
UniRef50_O01603 Cluster: Putative uncharacterized protein; n=2; ...    33   7.8  

>UniRef50_UPI000051A39F Cluster: PREDICTED: similar to
           Fumarylacetoacetase (Fumarylacetoacetate hydrolase)
           (Beta-diketonase) (FAA); n=1; Apis mellifera|Rep:
           PREDICTED: similar to Fumarylacetoacetase
           (Fumarylacetoacetate hydrolase) (Beta-diketonase) (FAA)
           - Apis mellifera
          Length = 373

 Score =  263 bits (644), Expect = 5e-69
 Identities = 121/180 (67%), Positives = 144/180 (80%)
 Frame = +1

Query: 169 MKSFIEYSSDSDFPIENLPYGVFTSDKNAQKHIGVAIGEWILDLNIISRLFDGPLLKSKQ 348
           MKSF+EYSSD DFPIENLPYGVF++  N QK IGVAIGE ILDL+ I+ LFDGPLLK+KQ
Sbjct: 1   MKSFVEYSSDCDFPIENLPYGVFSTKNNPQKRIGVAIGEEILDLSAIAHLFDGPLLKNKQ 60

Query: 349 NVFKEEKLNAFMALTKPHWIEARETLQKLLDVSSPALQNNAELREKAFVKQTDVQMHVPV 528
           +VF+ + LN FMAL +  WIEAR  LQ LL +S+P LQ  + +R  AFVKQ +  MH+P 
Sbjct: 61  DVFRRDYLNDFMALGRSAWIEARNKLQDLLSISNPTLQ-ESNIRSNAFVKQNEATMHLPA 119

Query: 529 EVGDYTDFYSSLQHATNVGIMFRGKEAALFENWKHLPVGYHGRSSSIVISGTPIHXPYGK 708
           ++GDYTDFYSS+ HATNVGIMFRGKE AL  NWKHLPV YHGR+SS+V+SGTPI  P G+
Sbjct: 120 KIGDYTDFYSSIYHATNVGIMFRGKENALMPNWKHLPVAYHGRASSVVVSGTPIRRPLGQ 179



 Score = 41.1 bits (92), Expect = 0.039
 Identities = 18/31 (58%), Positives = 20/31 (64%)
 Frame = +3

Query: 738 PHFGPXRLMDFDLEVGAFVGXPPHTGGKVCP 830
           P FGP RL+DF+LEV  FVG PP   G   P
Sbjct: 188 PVFGPSRLVDFELEVAIFVGGPPTNLGDAVP 218


>UniRef50_P35505 Cluster: Fumarylacetoacetase; n=108; cellular
           organisms|Rep: Fumarylacetoacetase - Mus musculus
           (Mouse)
          Length = 419

 Score =  232 bits (568), Expect = 8e-60
 Identities = 108/178 (60%), Positives = 129/178 (72%)
 Frame = +1

Query: 175 SFIEYSSDSDFPIENLPYGVFTSDKNAQKHIGVAIGEWILDLNIISRLFDGPLLKSKQNV 354
           SFI  + DSDFPI+NLPYGVF++  N +  IGVAIG+ ILDL++I  LF GP L   Q+V
Sbjct: 2   SFIPVAEDSDFPIQNLPYGVFSTQSNPKPRIGVAIGDQILDLSVIKHLFTGPALSKHQHV 61

Query: 355 FKEEKLNAFMALTKPHWIEARETLQKLLDVSSPALQNNAELREKAFVKQTDVQMHVPVEV 534
           F E  LN FM L +  W EAR +LQ LL  S   L+++ ELR++AF  Q    MH+P  +
Sbjct: 62  FDETTLNNFMGLGQAAWKEARASLQNLLSASQARLRDDKELRQRAFTSQASATMHLPATI 121

Query: 535 GDYTDFYSSLQHATNVGIMFRGKEAALFENWKHLPVGYHGRSSSIVISGTPIHXPYGK 708
           GDYTDFYSS QHATNVGIMFRGKE AL  NW HLPVGYHGR+SSIV+SGTPI  P G+
Sbjct: 122 GDYTDFYSSRQHATNVGIMFRGKENALLPNWLHLPVGYHGRASSIVVSGTPIRRPMGQ 179


>UniRef50_P16930 Cluster: Fumarylacetoacetase; n=33; cellular
           organisms|Rep: Fumarylacetoacetase - Homo sapiens
           (Human)
          Length = 419

 Score =  225 bits (551), Expect = 9e-58
 Identities = 106/178 (59%), Positives = 129/178 (72%)
 Frame = +1

Query: 175 SFIEYSSDSDFPIENLPYGVFTSDKNAQKHIGVAIGEWILDLNIISRLFDGPLLKSKQNV 354
           SFI  + DSDFPI NLPYGVF++  + +  IGVAIG+ ILDL+II  LF GP+L   Q+V
Sbjct: 2   SFIPVAEDSDFPIHNLPYGVFSTRGDPRPRIGVAIGDQILDLSIIKHLFTGPVLSKHQDV 61

Query: 355 FKEEKLNAFMALTKPHWIEARETLQKLLDVSSPALQNNAELREKAFVKQTDVQMHVPVEV 534
           F +  LN+FM L +  W EAR  LQ LL VS   L+++ ELR+ AF+ Q    MH+P  +
Sbjct: 62  FNQPTLNSFMGLGQAAWKEARVFLQNLLSVSQARLRDDTELRKCAFISQASATMHLPATI 121

Query: 535 GDYTDFYSSLQHATNVGIMFRGKEAALFENWKHLPVGYHGRSSSIVISGTPIHXPYGK 708
           GDYTDFYSS QHATNVGIMFR KE AL  NW HLPVGYHGR+SS+V+SGTPI  P G+
Sbjct: 122 GDYTDFYSSRQHATNVGIMFRDKENALMPNWLHLPVGYHGRASSVVVSGTPIRRPMGQ 179


>UniRef50_Q3DXY2 Cluster: Fumarylacetoacetase; n=1; Chloroflexus
           aurantiacus J-10-fl|Rep: Fumarylacetoacetase -
           Chloroflexus aurantiacus J-10-fl
          Length = 442

 Score =  186 bits (454), Expect = 5e-46
 Identities = 89/183 (48%), Positives = 117/183 (63%), Gaps = 3/183 (1%)
 Frame = +1

Query: 169 MKSFIEYSSDSDFPIENLPYGVFTSDKNAQKHIGVAIGEWILDLNIISR---LFDGPLLK 339
           + SF+  + DSDFP+ENLPYGVF         IGVAIGE++LDL +I     L   P+  
Sbjct: 29  LTSFVPVAPDSDFPLENLPYGVFRPRAGGPARIGVAIGEYVLDLAVIDEAGLLSATPV-- 86

Query: 340 SKQNVFKEEKLNAFMALTKPHWIEARETLQKLLDVSSPALQNNAELREKAFVKQTDVQMH 519
             + +F ++ LNAFMA     W   R  LQ+LL    P L++N  LR+ A + Q  + + 
Sbjct: 87  GGRGMFAQDSLNAFMAAGPTAWQAVRSVLQRLLTADEPTLRDNQVLRDAALLPQHTIDLL 146

Query: 520 VPVEVGDYTDFYSSLQHATNVGIMFRGKEAALFENWKHLPVGYHGRSSSIVISGTPIHXP 699
           +P  +GDYTDFYSSL HA+NVG M R     LF NW+HLPV YHGR+S++V+SGTPIH P
Sbjct: 147 LPAHIGDYTDFYSSLYHASNVGKMLRPDNPPLFPNWRHLPVAYHGRASTVVVSGTPIHRP 206

Query: 700 YGK 708
           YG+
Sbjct: 207 YGQ 209



 Score = 34.7 bits (76), Expect = 3.4
 Identities = 13/31 (41%), Positives = 19/31 (61%)
 Frame = +3

Query: 732 PXPHFGPXRLMDFDLEVGAFVGXPPHTGGKV 824
           P P +GP R +DF+LE+G F+G     G  +
Sbjct: 216 PAPVYGPTRALDFELELGMFIGPGNDLGSPI 246


>UniRef50_O65374 Cluster: F12F1.8 protein; n=7; Eukaryota|Rep:
           F12F1.8 protein - Arabidopsis thaliana (Mouse-ear cress)
          Length = 408

 Score =  177 bits (432), Expect = 2e-43
 Identities = 94/198 (47%), Positives = 127/198 (64%), Gaps = 18/198 (9%)
 Frame = +1

Query: 169 MKSFIEYSSDSDFPIENLPYGVFTSDKNAQKHIGVAIGEWILDLNIISR--LFDGPLLKS 342
           +KSFI+  SDS FPI+NLPYGVF  + N+     VAIG+ +LDL+ IS   LFDG +LK 
Sbjct: 4   LKSFIDVGSDSHFPIQNLPYGVFKPESNSTPRPAVAIGDLVLDLSAISEAGLFDGLILKD 63

Query: 343 KQNVFKEEKLNAFMALTKPHWIEARETLQKLLD----------------VSSPALQNNAE 474
             + F +  LN F+A+ +P W EAR TLQ++L                  + P L++N  
Sbjct: 64  A-DCFLQPNLNKFLAMGRPAWKEARSTLQRILSFLLFGFKVLVLVCFHAANEPILRDNDV 122

Query: 475 LREKAFVKQTDVQMHVPVEVGDYTDFYSSLQHATNVGIMFRGKEAALFENWKHLPVGYHG 654
           LR K+F + + V+M VP+ +GDYTDF++S+ HA N G+MFRG E A+  NW  LP+ YHG
Sbjct: 123 LRRKSFHQMSKVEMIVPMVIGDYTDFFASMHHAKNCGLMFRGPENAINPNWFRLPIAYHG 182

Query: 655 RSSSIVISGTPIHXPYGK 708
           R+SSIVISGT I  P G+
Sbjct: 183 RASSIVISGTDIIRPRGQ 200


>UniRef50_Q46UA3 Cluster: Fumarylacetoacetase; n=3;
           Proteobacteria|Rep: Fumarylacetoacetase - Ralstonia
           eutropha (strain JMP134) (Alcaligenes eutrophus)
          Length = 422

 Score =  169 bits (411), Expect = 9e-41
 Identities = 99/251 (39%), Positives = 136/251 (54%), Gaps = 4/251 (1%)
 Frame = +1

Query: 175 SFIEYSSD--SDFPIENLPYGVFTSDKNAQKHIGVAIGEWILDLNIISRLFDGPLLKSKQ 348
           S+IE ++D  + FP++NLPYG+F S K     +GVAIG  +LDL  +     G L  + +
Sbjct: 7   SWIESANDGKTHFPLQNLPYGIF-SVKGQAARVGVAIGNAVLDLAALDEA--GLLPVAAK 63

Query: 349 NVFKEEKLNAFMALTKPHWIEARETLQKLLDVSSPALQNNAELREKAFVKQTDVQMHVPV 528
             F    LN F+AL KP W E R+ L  LL  +  AL++NA LR++A V    V +H+PV
Sbjct: 64  GTFAAASLNRFIALGKPVWSETRQRLTALLSGADAALRDNAALRDRALVPMDQVMLHLPV 123

Query: 529 EVGDYTDFYSSLQHATNVGIMFRGKEAALFENWKHLPVGYHGRSSSIVISGTPIHXPYGK 708
           E+  YTDFYSS +HATNVG MFR  + AL  NW  +P+GY+GR+SS+V+SGT +  P G+
Sbjct: 124 EIPGYTDFYSSKEHATNVGRMFRDPDNALLPNWLEIPIGYNGRASSVVVSGTDLRRPNGQ 183

Query: 709 XXLSCXRCXRPTSVLXD*WTLTWKWGHLSAAPHTLGE--RSAPGPXNXFWFPAFDHWXAX 882
             L      RP            + G +      LGE   +A  P   F     + W A 
Sbjct: 184 IKL--PNEARPIFSACRKLDFELEVGFIVGKESALGEPVSTADAPNYMFGMVLLNDWSAR 241

Query: 883 DLXXGXTXPSG 915
           D+      P G
Sbjct: 242 DIQQWEYVPLG 252


>UniRef50_Q00770 Cluster: Fumarylacetoacetase; n=15;
           Pezizomycotina|Rep: Fumarylacetoacetase - Emericella
           nidulans (Aspergillus nidulans)
          Length = 431

 Score =  167 bits (406), Expect = 3e-40
 Identities = 79/186 (42%), Positives = 124/186 (66%), Gaps = 6/186 (3%)
 Frame = +1

Query: 169 MKSFIEYSSDSDFPIENLPYGVFTSDKNAQKHIGVAIGEWILDLNIISR---LFDGPLLK 339
           M S+++   +S F + N+P+G+ +S K + +   +AIG++ LDL+  +        P+++
Sbjct: 1   MASWLQIPKNSPFSLANIPFGIISSSKLSSRVPAIAIGDYALDLSKFASSGGFSQLPVIQ 60

Query: 340 SKQNVFKEEKLNAFMALTKPHWIEARETLQKLLDVSSP---ALQNNAELREKAFVKQTDV 510
              NVFKE  LNAF AL +P   + RE +QK+    +P    L++NA L+++A +  ++V
Sbjct: 61  PHLNVFKESTLNAFAALGRPVHRQVREYIQKVFSTETPFPQILRDNAALQKEALLPLSEV 120

Query: 511 QMHVPVEVGDYTDFYSSLQHATNVGIMFRGKEAALFENWKHLPVGYHGRSSSIVISGTPI 690
             H+P+++GDYTDFY+ L HA NVG++FRG + AL  N+KHLPV YHGR+SS+V SGTP+
Sbjct: 121 TNHLPMQIGDYTDFYAGLNHAYNVGVLFRGPDNALQPNYKHLPVAYHGRASSVVTSGTPL 180

Query: 691 HXPYGK 708
           H P G+
Sbjct: 181 HRPQGQ 186


>UniRef50_A0BKF7 Cluster: Chromosome undetermined scaffold_112,
           whole genome shotgun sequence; n=3;
           Oligohymenophorea|Rep: Chromosome undetermined
           scaffold_112, whole genome shotgun sequence - Paramecium
           tetraurelia
          Length = 430

 Score =  156 bits (378), Expect = 9e-37
 Identities = 90/260 (34%), Positives = 136/260 (52%), Gaps = 6/260 (2%)
 Frame = +1

Query: 163 RKMKSFIEYSSDSDFPIENLPYGVFTSDKNAQKHIGVAIGEWILDLNIISRL--FDGPLL 336
           +++++F+    DSDF I+N+P+GV  S  +        IG+ +++L  +  L  F+GPL 
Sbjct: 3   QEIQAFLLVPKDSDFTIKNIPFGV-ASKADGLPFPATIIGDSVINLAKLEELGYFNGPLF 61

Query: 337 KSK-QNVFKEEKLNAFMALTKPHWIEARETLQKLLDVSSPALQNNAELREKAFVKQTDVQ 513
            +    VF    LN F++L++P+W E R  +Q L    S  L+NN E+  +      D +
Sbjct: 62  STLGSKVFDNGNLNKFVSLSRPYWKEVRSQIQSLFSTGSQ-LENNKEVLAQVITPVQDTK 120

Query: 514 MHVPVEVGDYTDFYSSLQHATNVGIMFRGKEAALFENWKHLPVGYHGRSSSIVISGTPIH 693
            H+P+ +G+YTDFYSS  HA N+G + RG + A+  NW HLPVGYHGR SSIV+ GT I 
Sbjct: 121 NHLPITIGEYTDFYSSKNHAFNMGSIIRGPDNAMQPNWYHLPVGYHGRRSSIVVDGTDIR 180

Query: 694 XPYGKXXLSCXRCXRPTSVLXD*WTLTWKWGH-LSAAPHTLGE--RSAPGPXNXFWFPAF 864
            P+G+  +      +P+           + G  +  AP+ LGE  R        F F   
Sbjct: 181 RPWGQ--VKAPTAEKPSFTKCKRLDYELEIGAVIGGAPNNLGEPIRVNQAEDRVFGFVIL 238

Query: 865 DHWXAXDLXXGXTXPSGRSG 924
           + W A D+      P G  G
Sbjct: 239 NDWSARDVQVWEYVPLGPFG 258


>UniRef50_A7ENI0 Cluster: Putative uncharacterized protein; n=1;
           Sclerotinia sclerotiorum 1980|Rep: Putative
           uncharacterized protein - Sclerotinia sclerotiorum 1980
          Length = 439

 Score =  148 bits (358), Expect = 2e-34
 Identities = 77/190 (40%), Positives = 117/190 (61%), Gaps = 7/190 (3%)
 Frame = +1

Query: 169 MKSFIEYSSDSDFPIENLPYGVFTSDKNAQKHI-GVAIGEWILDLNIISRL--FDG-PLL 336
           +KS++    +SDF I N+P+G+ TS  +   H   + IG  +LDL   S+   F   P  
Sbjct: 4   LKSWLRIPPNSDFSILNIPFGIITSRHSQTIHRPAIRIGNHVLDLLAFSKSSGFQKLPSF 63

Query: 337 KSKQNVFKEEKLNAFMALTKPHWIEARETLQKLLDVSSP---ALQNNAELREKAFVKQTD 507
           K   +VF+E  LNAF AL +P   E R+ +Q++    +P    L++N E++ +  +K+ D
Sbjct: 64  KDHLSVFEEPNLNAFAALGQPVHREVRKYIQEVFKEDTPYPELLKDNEEVQRECLLKEGD 123

Query: 508 VQMHVPVEVGDYTDFYSSLQHATNVGIMFRGKEAALFENWKHLPVGYHGRSSSIVISGTP 687
            + H+P+ +GDYTDF++ + HA N G MFRG E AL  N+ H+P+GYHGR+SS+V+SGT 
Sbjct: 124 WKNHLPMRIGDYTDFFAGINHARNAGTMFRGAENALQPNYTHVPIGYHGRASSVVVSGTQ 183

Query: 688 IHXPYGKXXL 717
           I  P G+  L
Sbjct: 184 ITRPNGQIIL 193


>UniRef50_Q4PEP0 Cluster: Putative uncharacterized protein; n=1;
           Ustilago maydis|Rep: Putative uncharacterized protein -
           Ustilago maydis (Smut fungus)
          Length = 489

 Score =  132 bits (320), Expect = 9e-30
 Identities = 84/218 (38%), Positives = 113/218 (51%), Gaps = 38/218 (17%)
 Frame = +1

Query: 169 MKSFIEYSSDSDFPIENLPYGVFTSDKN-AQKHIGVAIGEWILDLNII------------ 309
           M   I+Y+++  F I NLPYG F +D + + +  GVAIG+WI+DL  +            
Sbjct: 1   MNCIIDYAANHPFSIANLPYGSFYTDNDPSTQRCGVAIGDWIVDLKALSYTTFCPGGVEP 60

Query: 310 ----------SRLFDGPLLKSKQ--NVFKEEKLNAFMALTKPHWIEARETLQKLLDVSSP 453
                     + LF    L      +  K+  LN FMAL+K  W+  R  LQ LL   S 
Sbjct: 61  EVFRSVSKIPATLFSSDRLAELYLTSCGKQTTLNLFMALSKSTWLSVRLHLQSLLTHPSA 120

Query: 454 ALQN------NAE-------LREKAFVKQTDVQMHVPVEVGDYTDFYSSLQHATNVGIMF 594
             Q+      N E       L +   + Q+   M +P  +GDYTDFY+S++HATN G + 
Sbjct: 121 ISQDTVITPTNLERSSPSTVLSQPLLIPQSAATMCLPCTIGDYTDFYTSIEHATNCGTLL 180

Query: 595 RGKEAALFENWKHLPVGYHGRSSSIVISGTPIHXPYGK 708
           RG+   L  NWKHLPV YHGR SSIV+SGTPI  P G+
Sbjct: 181 RGRSQPLLPNWKHLPVAYHGRCSSIVVSGTPIRRPVGQ 218


>UniRef50_Q6EMI8 Cluster: Fumarylacetoacetase; n=16;
           Proteobacteria|Rep: Fumarylacetoacetase - Pseudomonas
           putida
          Length = 430

 Score =  131 bits (317), Expect = 2e-29
 Identities = 76/182 (41%), Positives = 114/182 (62%), Gaps = 3/182 (1%)
 Frame = +1

Query: 172 KSFIEYSSD-SDFPIENLPYGVFTSDKNAQKHIGVAIGEWILDLNII--SRLFDGPLLKS 342
           +S++E+++  SDFP++NLP G+F+    A++  GVAIG+ ILDL  +  + LFDG   K+
Sbjct: 8   RSWVEHANGHSDFPLQNLPLGIFSRPGEARR-CGVAIGDAILDLEAVLAAGLFDGAA-KA 65

Query: 343 KQNVFKEEKLNAFMALTKPHWIEARETLQKLLDVSSPALQNNAELREKAFVKQTDVQMHV 522
                +   LNAF AL +   +  RE LQ LL   S   ++ A L + A    +  Q+HV
Sbjct: 66  AVEATRGGALNAFFALGRSARVALRERLQVLLGEHS---EHQAAL-QAALYPASACQLHV 121

Query: 523 PVEVGDYTDFYSSLQHATNVGIMFRGKEAALFENWKHLPVGYHGRSSSIVISGTPIHXPY 702
           P ++GDYTDFY  ++HA NVG +FR  +  L  N+K++P+GYHGR+S+I  SGT +  P 
Sbjct: 122 PAQIGDYTDFYVGIEHAKNVGKLFR-PDNPLLPNYKYVPIGYHGRASTIRPSGTDVRRPK 180

Query: 703 GK 708
           G+
Sbjct: 181 GQ 182


>UniRef50_UPI00005A0527 Cluster: PREDICTED: similar to
           Fumarylacetoacetase (Fumarylacetoacetate hydrolase)
           (Beta-diketonase) (FAA); n=1; Canis lupus
           familiaris|Rep: PREDICTED: similar to
           Fumarylacetoacetase (Fumarylacetoacetate hydrolase)
           (Beta-diketonase) (FAA) - Canis familiaris
          Length = 406

 Score =  126 bits (303), Expect = 1e-27
 Identities = 59/117 (50%), Positives = 78/117 (66%)
 Frame = +1

Query: 175 SFIEYSSDSDFPIENLPYGVFTSDKNAQKHIGVAIGEWILDLNIISRLFDGPLLKSKQNV 354
           SF+  + DSDFPI NLPYGVF++  N ++ IGVAIG+ ILDL++I  LF GP+L   Q+V
Sbjct: 2   SFVAVAEDSDFPIHNLPYGVFSTPGNPRQRIGVAIGDQILDLSVIKHLFTGPILSKHQDV 61

Query: 355 FKEEKLNAFMALTKPHWIEARETLQKLLDVSSPALQNNAELREKAFVKQTDVQMHVP 525
           F +  LN+FM L +  W EAR  LQ LL  S   L+++ ELR +AF  Q    MH+P
Sbjct: 62  FNQPALNSFMGLGQAAWKEARAFLQNLLSASHARLRDDTELRRRAFTDQASAVMHLP 118



 Score =  109 bits (263), Expect = 7e-23
 Identities = 54/95 (56%), Positives = 62/95 (65%)
 Frame = +1

Query: 424 LQKLLDVSSPALQNNAELREKAFVKQTDVQMHVPVEVGDYTDFYSSLQHATNVGIMFRGK 603
           ++  L   SPA +   E   K F +  D         GDYTDFYSS QHATNVGIMFRGK
Sbjct: 130 VENALPEDSPAREIGGEEASKYF-QDLDSDSGGENRAGDYTDFYSSRQHATNVGIMFRGK 188

Query: 604 EAALFENWKHLPVGYHGRSSSIVISGTPIHXPYGK 708
           E AL  NW HLPVGYHGR+SS+V+SGTPI  P G+
Sbjct: 189 ENALMPNWLHLPVGYHGRASSVVVSGTPIRRPMGQ 223


>UniRef50_A1SEE6 Cluster: Fumarylacetoacetase; n=10;
           Actinomycetales|Rep: Fumarylacetoacetase - Nocardioides
           sp. (strain BAA-499 / JS614)
          Length = 391

 Score =  125 bits (301), Expect = 2e-27
 Identities = 84/253 (33%), Positives = 124/253 (49%), Gaps = 4/253 (1%)
 Frame = +1

Query: 169 MKSFIEYSSDSDFPIENLPYGVFTSDKNAQKHIGVAIGEWILDLNIISRLFDGPLLKSKQ 348
           M++++  ++ S F +++LPYGVF S    +  +GV IG+ +LDL  ++       +    
Sbjct: 1   MRTWVPGAAGSGFDVDHLPYGVF-SRAGEEPRVGVRIGDQVLDLAPVA----AAEMLDVH 55

Query: 349 NVFKEEKLNAFMALTKPHWIEARETLQKLLDVSSPALQNNAE--LREKAFVKQTDVQMHV 522
            V +E  LNA MA       E R   + +    +  L + AE  L E   V   +V +H+
Sbjct: 56  RVLEERSLNALMA-------EGRRVRESVRAWVTGLLSDEAERDLVEPHLVPLAEVALHL 108

Query: 523 PVEVGDYTDFYSSLQHATNVGIMFRGKEAALFENWKHLPVGYHGRSSSIVISGTPIHXPY 702
           PVEV DY DFY+S  HA+NVG +FR     L  NWKHLPVGYHGR+ ++V SGTP+  P 
Sbjct: 109 PVEVADYVDFYASEHHASNVGRIFRPDAEPLLPNWKHLPVGYHGRAGTVVASGTPVVRPC 168

Query: 703 GKXXLSCXRCXRPTSVLXD*WTLTWKWGHLSAAPHTLGE--RSAPGPXNXFWFPAFDHWX 876
           G+          P++ L     +  + G +   P  LG   R      + F     + W 
Sbjct: 169 GQRRGDAGPTYGPSTRL----DIEAELGFVVGTPSELGTPVRYDAFADHVFGVVGLNDWS 224

Query: 877 AXDLXXGXTXPSG 915
           A D+      P G
Sbjct: 225 ARDIQAWEYVPLG 237


>UniRef50_A6VYW9 Cluster: Fumarylacetoacetase; n=2;
           Proteobacteria|Rep: Fumarylacetoacetase - Marinomonas
           sp. MWYL1
          Length = 429

 Score =  120 bits (289), Expect = 5e-26
 Identities = 82/241 (34%), Positives = 114/241 (47%), Gaps = 3/241 (1%)
 Frame = +1

Query: 202 DFPIENLPYGVFTSDKNAQKHIGVAIGEWILDLNIISRL-FDGPLLKSKQNVFKEEKLNA 378
           +FP+ NLPY VF+S      HIGV IG+ I +L+ +  +     L    +   K+  LN 
Sbjct: 19  EFPLANLPYAVFSSADQIH-HIGVGIGDKIANLSALEEVGLFAELDPCLREAVKQNALNQ 77

Query: 379 FMALTKPHWIEARETLQKLLDVSSPALQNNAELREKAFVKQTDVQMHVPVEVGDYTDFYS 558
            M L    W   R  L +L   S+ A Q+  E      + Q++V  H+P ++GDYTDFY+
Sbjct: 78  LMGLGHTQWHALRLRLIELF--SNSAYQSKVEA---CLIPQSEVAFHLPCQIGDYTDFYT 132

Query: 559 SLQHATNVGIMFRGKEAALFENWKHLPVGYHGRSSSIVISGTPIHXPYGKXXLSCXRCXR 738
           S+ HAT VG +FR  +  L  N+K +P+GYHGR+SSI ISG     P G+  L      R
Sbjct: 133 SVHHATRVGSLFR-PDNPLLPNYKWIPIGYHGRASSIRISGEAFKRPAGQ--LKAPDAER 189

Query: 739 PTSVLXD*WTLTWKWGHLSAAPHTLGE--RSAPGPXNXFWFPAFDHWXAXDLXXGXTXPS 912
           P   L        + G        LG     A    + F    F+ W A D+      P 
Sbjct: 190 PVLELCKRLDYELELGIFIGKGSQLGTPISMADAEQHVFGVSMFNDWSARDIQAWEYQPL 249

Query: 913 G 915
           G
Sbjct: 250 G 250


>UniRef50_Q2UHQ1 Cluster: RIB40 genomic DNA, SC023; n=1; Aspergillus
           oryzae|Rep: RIB40 genomic DNA, SC023 - Aspergillus
           oryzae
          Length = 457

 Score =  113 bits (271), Expect = 8e-24
 Identities = 59/172 (34%), Positives = 101/172 (58%), Gaps = 2/172 (1%)
 Frame = +1

Query: 196 DSDFPIENLPYGVFTSDKNAQKHIGVAIGEWILDL-NIISR-LFDGPLLKSKQNVFKEEK 369
           DS FP+ N+P+G+F++ ++     G AIG++++DL  + +R           Q++F+E  
Sbjct: 17  DSPFPVSNIPFGIFSTAEDPTPRPGAAIGDYVIDLFRVANRGALTIDYADGAQDIFREPT 76

Query: 370 LNAFMALTKPHWIEARETLQKLLDVSSPALQNNAELREKAFVKQTDVQMHVPVEVGDYTD 549
           LN F AL +P   + R+ +Q L+  +   L N  + + K  + +  V MH+P  +G +TD
Sbjct: 77  LNRFAALPRPVRSKIRKDIQALIVNADSPLYNQTD-QAKLLIPRVAVSMHLPFSMGGFTD 135

Query: 550 FYSSLQHATNVGIMFRGKEAALFENWKHLPVGYHGRSSSIVISGTPIHXPYG 705
           +  SL+H TNVG +       +  ++++ P+ Y+GR+SS+V SGTPI  PYG
Sbjct: 136 YTCSLEHVTNVGRV--AGFGDIPPSFRNQPLAYNGRASSVVPSGTPIQRPYG 185


>UniRef50_Q7W190 Cluster: Fumarylacetoacetase; n=9;
           Proteobacteria|Rep: Fumarylacetoacetase - Bordetella
           parapertussis
          Length = 452

 Score =  108 bits (260), Expect = 2e-22
 Identities = 68/164 (41%), Positives = 91/164 (55%), Gaps = 4/164 (2%)
 Frame = +1

Query: 190 SSDSDFPIENLPYGVFTSDKNAQKHI--GVAIGEWILDLNIISRL--FDGPLLKSKQNVF 357
           ++D+ FPI+NLP+  F   K  Q     GVAIG+ I+DL  ++    FDG    +     
Sbjct: 36  AADTSFPIQNLPFAAFRR-KGTQDPFRPGVAIGDAIVDLAALAAQAPFDGTAAAALA-AC 93

Query: 358 KEEKLNAFMALTKPHWIEARETLQKLLDVSSPALQNNAELREKAFVKQTDVQMHVPVEVG 537
           + E+LNA MAL + HW   R  L + L   S ALQ   E      V Q + +   P  +G
Sbjct: 94  QGERLNALMALDQAHWSALRLALSRALRTGS-ALQGRIE---PLLVAQAEAEYTTPAHIG 149

Query: 538 DYTDFYSSLQHATNVGIMFRGKEAALFENWKHLPVGYHGRSSSI 669
           DYTDFY S+ HAT VG  FR  +  L  N+K +P+GYHGR+SSI
Sbjct: 150 DYTDFYISVHHATAVGKQFR-PDNPLLPNYKWVPIGYHGRASSI 192


>UniRef50_Q4P904 Cluster: Putative uncharacterized protein; n=1;
           Ustilago maydis|Rep: Putative uncharacterized protein -
           Ustilago maydis (Smut fungus)
          Length = 456

 Score =  108 bits (259), Expect = 2e-22
 Identities = 61/187 (32%), Positives = 101/187 (54%), Gaps = 7/187 (3%)
 Frame = +1

Query: 166 KMKSFIEYSSDSDFPIENLPYGVFTSDKNAQKHIGVAIGEWILDLNIISR-----LFDGP 330
           +++S + Y++D  FP+E+LP+ VF++  N  +   V I + ++DL  +S        + P
Sbjct: 9   RLESIVPYAADHPFPLESLPWTVFSTTDNPVRRCAVRIADQLVDLVQLSNKAPSAFSEQP 68

Query: 331 L-LKSKQNVFKEEKLNAFMALTKPHWIEARETLQKLLDVSSPALQNNAELREKAFVKQTD 507
           +  +   ++F +  LNA++A ++      R  LQ +L   S   ++  +L     V    
Sbjct: 69  VSAECASSLFSQPTLNAYLAQSRQVHKTFRRFLQTVLSSDSSIFKSQPQLLNDILVLVEK 128

Query: 508 VQMHVPVEVGDYTDFYSSLQHATNVG-IMFRGKEAALFENWKHLPVGYHGRSSSIVISGT 684
             +H+P++VGDYTDF +S  H T+ G +MF      L + W  LP+ YHGRSSS+V SGT
Sbjct: 129 ATLHLPIQVGDYTDFCASKYHCTSTGRLMF---TRPLEDQWYQLPIDYHGRSSSLVASGT 185

Query: 685 PIHXPYG 705
               P G
Sbjct: 186 SFRRPRG 192


>UniRef50_Q39M11 Cluster: Fumarylacetoacetase; n=17; Bacteria|Rep:
           Fumarylacetoacetase - Burkholderia sp. (strain 383)
           (Burkholderia cepacia (strain ATCC 17760/ NCIB 9086 /
           R18194))
          Length = 440

 Score =  100 bits (240), Expect = 5e-20
 Identities = 64/173 (36%), Positives = 91/173 (52%), Gaps = 3/173 (1%)
 Frame = +1

Query: 199 SDFPIENLPYGVFTSDKNAQK-HIGVAIGEWILDLNIISRL--FDGPLLKSKQNVFKEEK 369
           +DFP++NLP GVF      +    G+AIG+ I+DL  + +    DG  L + +       
Sbjct: 23  TDFPLQNLPLGVFRRRGGGETWRGGIAIGDQIVDLAALQQAGCMDGLALDAVRAA-TATT 81

Query: 370 LNAFMALTKPHWIEARETLQKLLDVSSPALQNNAELREKAFVKQTDVQMHVPVEVGDYTD 549
           LNA + +    W   R  L +LL   SP   +   +R K  V Q + +  VPV +GDYTD
Sbjct: 82  LNALLEMGPTAWQALRHALFELLRAGSP---HEPGVR-KTLVSQAEAEYAVPVRIGDYTD 137

Query: 550 FYSSLQHATNVGIMFRGKEAALFENWKHLPVGYHGRSSSIVISGTPIHXPYGK 708
           FY+SL HA N     R    A+  N+  LP+ YHGR SSI +SG  ++ P G+
Sbjct: 138 FYTSLDHAVNCS---RPLGMAISPNFDWLPIAYHGRVSSIGVSGQQVYRPMGQ 187


>UniRef50_Q13R26 Cluster: Fumarylacetoacetase; n=1; Burkholderia
           xenovorans LB400|Rep: Fumarylacetoacetase - Burkholderia
           xenovorans (strain LB400)
          Length = 450

 Score =  100 bits (239), Expect = 6e-20
 Identities = 63/184 (34%), Positives = 97/184 (52%), Gaps = 5/184 (2%)
 Frame = +1

Query: 172 KSFIEYSS--DSDFPIENLPYGVFTSDKNAQKHIGVAIGEWILDLNII--SRLFD-GPLL 336
           +S+IE ++  D+DFPI+NLP+G F  ++N +   GVAIGE ++DL  +  S L + G   
Sbjct: 13  RSWIESANLPDADFPIQNLPFGAF--ERNGEARTGVAIGEHVVDLRALRDSGLVEAGSDA 70

Query: 337 KSKQNVFKEEKLNAFMALTKPHWIEARETLQKLLDVSSPALQNNAELREKAFVKQTDVQM 516
                      LN  MA+   +    R  L +LL   +P   N     E    +  ++ +
Sbjct: 71  ALACEAASGATLNRLMAMGPRYSGALRAALSELLKSDAPQRANVQRQAEALLPRIDEIAL 130

Query: 517 HVPVEVGDYTDFYSSLQHATNVGIMFRGKEAALFENWKHLPVGYHGRSSSIVISGTPIHX 696
            +P EVGDY+DF +SL H    G  ++G    L   +K LP+ YHGR+SS+  SG  +  
Sbjct: 131 RLPCEVGDYSDFLTSLHHTERHG-RYKGLADPLPPAFKSLPIAYHGRASSLRASGGEVRR 189

Query: 697 PYGK 708
           P+G+
Sbjct: 190 PHGQ 193


>UniRef50_A4QQB2 Cluster: Putative uncharacterized protein; n=3;
           Pezizomycotina|Rep: Putative uncharacterized protein -
           Magnaporthe grisea (Rice blast fungus) (Pyricularia
           grisea)
          Length = 779

 Score = 81.8 bits (193), Expect = 2e-14
 Identities = 58/171 (33%), Positives = 83/171 (48%), Gaps = 4/171 (2%)
 Frame = +1

Query: 205 FPIENLPYGVFTSDKNAQKHIGVAIGEWILDLNIISRLFDGPLLKSKQN----VFKEEKL 372
           F + N+P+G+ +S +         +     D+  + +L++  LL S  +    VFK   L
Sbjct: 15  FSVVNIPFGIASSPRFPSPQPATRVDN---DVIFLCKLYEQGLLSSVPDLPAGVFKYSTL 71

Query: 373 NAFMALTKPHWIEARETLQKLLDVSSPALQNNAELREKAFVKQTDVQMHVPVEVGDYTDF 552
           NAF AL K      RE +Q      S +    +E RE      + V MH+PV V D+TDF
Sbjct: 72  NAFAALPKTVHSAVREAIQNAWREGSVS----SESREDV----SSVTMHLPVHVSDFTDF 123

Query: 553 YSSLQHATNVGIMFRGKEAALFENWKHLPVGYHGRSSSIVISGTPIHXPYG 705
             SL+H  N G +     A     + H P  Y GR+SS+V+SGTPI  P G
Sbjct: 124 SCSLEHVKNAGRIVVNN-ANPPPGFFHFPTAYAGRASSVVVSGTPIERPLG 173


>UniRef50_A2QIN6 Cluster: Remark: Hereditary tyrosinemia type 1;
           n=3; Trichocomaceae|Rep: Remark: Hereditary tyrosinemia
           type 1 - Aspergillus niger
          Length = 405

 Score = 80.6 bits (190), Expect = 5e-14
 Identities = 55/175 (31%), Positives = 90/175 (51%), Gaps = 4/175 (2%)
 Frame = +1

Query: 193 SDSDFPIENLPYGVFTSDKNAQKHIGVAIGEWILDLNIISRLFDGPLLKS----KQNVFK 360
           +++ F I+NLPYGV ++ +         + + ++DL+ + +  DG   KS    K +VF 
Sbjct: 4   TETPFTIDNLPYGVISTAETPTPRCATVLEDDVIDLSALEK--DG-YFKSIPGLKGDVFS 60

Query: 361 EEKLNAFMALTKPHWIEARETLQKLLDVSSPALQNNAELREKAFVKQTDVQMHVPVEVGD 540
              LN F +L K   +  R  L  LL        ++ ++R+K  +  + VQ H+P+E  +
Sbjct: 61  MPTLNKFASLPKETHVRTRAALVDLL--------SDNDIRKKYAIPLSTVQNHLPMETKN 112

Query: 541 YTDFYSSLQHATNVGIMFRGKEAALFENWKHLPVGYHGRSSSIVISGTPIHXPYG 705
           ++DFY S +H  NV             +W  +P  Y+GR SS+ ISGTPI  P+G
Sbjct: 113 FSDFYCSFEHTRNV------------PSWFVIPSVYNGRQSSLRISGTPIRRPWG 155


>UniRef50_A1DCJ6 Cluster: Fumarylacetoacetate hydrolase; n=3;
           Trichocomaceae|Rep: Fumarylacetoacetate hydrolase -
           Neosartorya fischeri (strain ATCC 1020 / DSM 3700 / NRRL
           181)(Aspergillus fischerianus (strain ATCC 1020 / DSM
           3700 / NRRL 181))
          Length = 416

 Score = 80.6 bits (190), Expect = 5e-14
 Identities = 57/169 (33%), Positives = 80/169 (47%), Gaps = 2/169 (1%)
 Frame = +1

Query: 205 FPIENLPYGVFTSDKNAQKHIGVAIGEWILDLNIISR--LFDGPLLKSKQNVFKEEKLNA 378
           F I NLP+GV +S ++ +      +   ++ L  + R  LF   +      VF    LNA
Sbjct: 10  FSINNLPFGVASSSQHPRPQCVTRLSNTVIFLGDLQRAGLFR-QVTSLPGGVFDNPTLNA 68

Query: 379 FMALTKPHWIEARETLQKLLDVSSPALQNNAELREKAFVKQTDVQMHVPVEVGDYTDFYS 558
           F AL K    + R+ LQ  L  S        +L   +    T V+MH+PV +  +TDF  
Sbjct: 69  FAALNKQVHKQVRQALQSALQDSGVE-----KLPTGSTEPTTAVRMHLPVSIPAFTDFSC 123

Query: 559 SLQHATNVGIMFRGKEAALFENWKHLPVGYHGRSSSIVISGTPIHXPYG 705
           SL H  N G      +      + H P+GY GR+S+IV SGTPI  P G
Sbjct: 124 SLNHVKNAGRAILNDDTPP-PGFFHFPIGYGGRASTIVPSGTPITRPLG 171


>UniRef50_Q0V4X9 Cluster: Putative uncharacterized protein; n=1;
           Phaeosphaeria nodorum|Rep: Putative uncharacterized
           protein - Phaeosphaeria nodorum (Septoria nodorum)
          Length = 407

 Score = 72.9 bits (171), Expect = 1e-11
 Identities = 50/174 (28%), Positives = 82/174 (47%), Gaps = 1/174 (0%)
 Frame = +1

Query: 190 SSDSDFPIENLPYGVFTSDKNAQKHIGVAIGEWILDLN-IISRLFDGPLLKSKQNVFKEE 366
           S  S F I N+PYG+ +S    +      I + ++ L+ + S      + K   + F + 
Sbjct: 4   SYTSHFGINNIPYGIASSSSRPKPQAVTRIADTVIFLSELASTPAFQSISKDLVSTFLQP 63

Query: 367 KLNAFMALTKPHWIEARETLQKLLDVSSPALQNNAELREKAFVKQTDVQMHVPVEVGDYT 546
            LN F AL KP   + R  +Q     S      + +  E      ++V +H+PV++GD+T
Sbjct: 64  TLNTFAALPKPLQSQVRSAIQNAYTSSQ-----HTDFSEDI----SNVTLHMPVQIGDFT 114

Query: 547 DFYSSLQHATNVGIMFRGKEAALFENWKHLPVGYHGRSSSIVISGTPIHXPYGK 708
           D+ +S+ H  N      G  +      K+ PVGY GR SSI ++ T +  P G+
Sbjct: 115 DYSASVNHVLNASEAITGTRSQPPAYHKY-PVGYAGRCSSITLAPTSVVRPLGQ 167


>UniRef50_A2QEA7 Cluster: Catalytic activity: 4-fumarylacetoacetate
           + H(2)O = acetoacetate + fumarate; n=2;
           Trichocomaceae|Rep: Catalytic activity:
           4-fumarylacetoacetate + H(2)O = acetoacetate + fumarate
           - Aspergillus niger
          Length = 420

 Score = 70.1 bits (164), Expect = 7e-11
 Identities = 45/162 (27%), Positives = 75/162 (46%), Gaps = 2/162 (1%)
 Frame = +1

Query: 226 YGVFTSDKNAQKHIGVAIGEWILDLNIISR--LFDGPLLKSKQNVFKEEKLNAFMALTKP 399
           YG+ +S  +        +   ++ L+ +    LF   +     N+F    LN F +L + 
Sbjct: 1   YGIASSPSHPTPQCATRLNNTVIFLSDLQSAGLFSS-ITSLPDNIFSNTTLNPFSSLPRT 59

Query: 400 HWIEARETLQKLLDVSSPALQNNAELREKAFVKQTDVQMHVPVEVGDYTDFYSSLQHATN 579
              + R  LQ +L  S+ +L       E +    T V MH+PV +  +TD+ +SL H  +
Sbjct: 60  TQTQVRHVLQSILQTSTSSLP------ESSTADITTVTMHLPVSIPSFTDYSASLPHNQH 113

Query: 580 VGIMFRGKEAALFENWKHLPVGYHGRSSSIVISGTPIHXPYG 705
            G +     A     + H P+GY GR+S+I +SG P+  P G
Sbjct: 114 AGQIILNHPAPP-PAFFHFPIGYAGRASTISVSGAPVTRPSG 154


>UniRef50_Q2HI94 Cluster: Putative uncharacterized protein; n=1;
           Chaetomium globosum|Rep: Putative uncharacterized
           protein - Chaetomium globosum (Soil fungus)
          Length = 440

 Score = 64.1 bits (149), Expect = 5e-09
 Identities = 53/190 (27%), Positives = 86/190 (45%), Gaps = 22/190 (11%)
 Frame = +1

Query: 205 FPIENLPYGVFTSDKNAQKHIGVAIGEWILDLN---IISRLFDGPLLKSKQNVFKEEKLN 375
           F   N+P+G+ +S K+ Q      +G  ++ L+     S LF+G +    + +F +E LN
Sbjct: 10  FSARNIPFGIASSTKHPQPQAVTRVGNSVIFLHECHTSSELFEG-IDGLPRRIFADETLN 68

Query: 376 AFMALTKPHWIEARETLQKLLDVSSPALQNNAELREKAFVKQTDVQMHVPVEVGDYT--- 546
            F AL K      R  +Q +    +  +   ++L        T+V+MH+P+ VGD+    
Sbjct: 69  HFAALPKATHRNVRGAIQSVCQNGNLDI---SKLLPGCVEDITEVEMHMPITVGDFAGTI 125

Query: 547 ----------------DFYSSLQHATNVGIMFRGKEAALFENWKHLPVGYHGRSSSIVIS 678
                           DF  SL H  N G +    +      + H P+ Y GR+SS+V+S
Sbjct: 126 PLRPPPIIQARLLTTPDFSCSLIHGKNAGRIV-VNDPRPPPAFFHFPIAYQGRASSVVVS 184

Query: 679 GTPIHXPYGK 708
           GT I  P G+
Sbjct: 185 GTDIERPQGQ 194


>UniRef50_UPI00003B90DC Cluster: UPI00003B90DC related cluster; n=1;
           unknown|Rep: UPI00003B90DC UniRef100 entry - unknown
          Length = 128

 Score = 58.0 bits (134), Expect = 3e-07
 Identities = 20/42 (47%), Positives = 34/42 (80%)
 Frame = +1

Query: 169 MKSFIEYSSDSDFPIENLPYGVFTSDKNAQKHIGVAIGEWIL 294
           + SFI+ S  SDFPI+NLPYG+F++  + ++ +GVA+G+W++
Sbjct: 5   LSSFIDVSPQSDFPIQNLPYGIFSTTVHGKRRVGVALGDWVM 46


>UniRef50_Q5P7D0 Cluster: General (Type II) secretion pathway (GSP)
           D protein; n=3; Rhodocyclaceae|Rep: General (Type II)
           secretion pathway (GSP) D protein - Azoarcus sp. (strain
           EbN1) (Aromatoleum aromaticum (strain EbN1))
          Length = 771

 Score = 37.9 bits (84), Expect = 0.36
 Identities = 23/69 (33%), Positives = 36/69 (52%)
 Frame = +1

Query: 331 LLKSKQNVFKEEKLNAFMALTKPHWIEARETLQKLLDVSSPALQNNAELREKAFVKQTDV 510
           L+KSK ++F +EKLN  +    P  +   E L   LDV+ P +    E+ E A  K  ++
Sbjct: 291 LVKSK-DMFIDEKLNLLVIKDTPQAVRLAERLLASLDVAEPEVMLEVEVLEVARSKLREL 349

Query: 511 QMHVPVEVG 537
            +  P E+G
Sbjct: 350 GLDFPDEIG 358


>UniRef50_A7S2R3 Cluster: Predicted protein; n=1; Nematostella
           vectensis|Rep: Predicted protein - Nematostella
           vectensis
          Length = 726

 Score = 35.9 bits (79), Expect = 1.5
 Identities = 32/128 (25%), Positives = 52/128 (40%), Gaps = 5/128 (3%)
 Frame = +1

Query: 214 ENLPYGVFTSDKNAQKHI-GVAIGEWILDLNIISRLFDGPLLKSKQNVFKEEKLNAFMAL 390
           E++P  V+   K     + G+       D+N+    F   + +    +F  +K N++M L
Sbjct: 66  ESIPESVYKQYKKWCGQVPGLGFNSGKYDINMNKEYFVKHMTEQAGEIFVAKKENSYMFL 125

Query: 391 TKPHW--IEARETLQKLLDVSSPALQNNAELREKAFVKQTDVQMHVPVEVG--DYTDFYS 558
           T   +  ++ R  L   L        NN E ++  F  +          VG  +Y DFYS
Sbjct: 126 TTDQFKFLDVRSYLAPGLSFDKWCKANNCEAQKLVFPYEWLDSYEKLSHVGPVEYKDFYS 185

Query: 559 SLQHATNV 582
           SLQ    V
Sbjct: 186 SLQQKITV 193


>UniRef50_Q0CBB3 Cluster: Predicted protein; n=1; Aspergillus
           terreus NIH2624|Rep: Predicted protein - Aspergillus
           terreus (strain NIH 2624)
          Length = 80

 Score = 34.7 bits (76), Expect = 3.4
 Identities = 13/37 (35%), Positives = 23/37 (62%)
 Frame = +1

Query: 466 NAELREKAFVKQTDVQMHVPVEVGDYTDFYSSLQHAT 576
           N E +      +  V+MH+P+++G +TD+  SL+H T
Sbjct: 9   NPEFQSFLLHHKESVKMHLPMQIGGFTDYMCSLEHYT 45


>UniRef50_Q21YQ2 Cluster: Type III restriction enzyme, res subunit;
            n=1; Rhodoferax ferrireducens T118|Rep: Type III
            restriction enzyme, res subunit - Rhodoferax
            ferrireducens (strain DSM 15236 / ATCC BAA-621 / T118)
          Length = 1289

 Score = 33.9 bits (74), Expect = 5.9
 Identities = 17/49 (34%), Positives = 28/49 (57%)
 Frame = +1

Query: 403  WIEARETLQKLLDVSSPALQNNAELREKAFVKQTDVQMHVPVEVGDYTD 549
            W+ +RE L  +LD + PAL  +A+ +  AF +Q  V  H+  ++ D  D
Sbjct: 924  WLSSRERLSGILDFTKPALAKHADEKRAAFAEQ--VVKHLASKLRDDDD 970


>UniRef50_Q00UW0 Cluster: Homology to unknown gene; n=2;
           Ostreococcus|Rep: Homology to unknown gene -
           Ostreococcus tauri
          Length = 1143

 Score = 33.9 bits (74), Expect = 5.9
 Identities = 21/62 (33%), Positives = 32/62 (51%), Gaps = 5/62 (8%)
 Frame = +3

Query: 483 KGFREADGRTNARAC*SRRLH-----RLLFVAAARYQRRHNVQGKGGRSVRELETSTGGL 647
           +G R  DG  +A A  +RRL+     +     A  +  R + +  GG+S+R  +TS GG 
Sbjct: 217 RGSRSVDGCRSADASGARRLNSPSRAKTAEKMARAWDERRSARAMGGKSMRGDKTSDGGS 276

Query: 648 SW 653
           SW
Sbjct: 277 SW 278


>UniRef50_A7RT37 Cluster: Predicted protein; n=1; Nematostella
            vectensis|Rep: Predicted protein - Nematostella vectensis
          Length = 1020

 Score = 33.9 bits (74), Expect = 5.9
 Identities = 31/128 (24%), Positives = 51/128 (39%), Gaps = 5/128 (3%)
 Frame = +1

Query: 214  ENLPYGVFTSDKNAQKHIGV-AIGEWILDLNIISRLFDGPLLKSKQNVFKEEKLNAFMAL 390
            E++P  V+   K   + + V        D+N++   F   + K    +F  +K + +M L
Sbjct: 680  ESIPESVYEQYKKWCEQVPVLGFNSGKYDINMVKEYFVKHMTKQAGEIFAAKKESNYMFL 739

Query: 391  TKPHW--IEARETLQKLLDVSSPALQNNAELREKAFVKQTDVQMHVPVEVG--DYTDFYS 558
            T   +  ++    L   L        NN E ++  F  +          VG  +Y DFYS
Sbjct: 740  TTDRFKFLDVMSYLAPGLSFDKWCKANNCEAQKLVFPYEWLDSYEKLSHVGPVEYKDFYS 799

Query: 559  SLQHATNV 582
            SLQ    V
Sbjct: 800  SLQQKITV 807


>UniRef50_O96216 Cluster: Putative uncharacterized protein PFB0615c;
            n=1; Plasmodium falciparum 3D7|Rep: Putative
            uncharacterized protein PFB0615c - Plasmodium falciparum
            (isolate 3D7)
          Length = 2385

 Score = 33.5 bits (73), Expect = 7.8
 Identities = 23/112 (20%), Positives = 51/112 (45%), Gaps = 1/112 (0%)
 Frame = +1

Query: 193  SDSDFPIENLPYGVFTSDKNAQKHIGVAIGEWILDLNIISRLFDGPLLKSKQNVFKEEKL 372
            +D  +  + +   VF    N+ +HI   + +WI++ N  S   +  L+K+   VF + K 
Sbjct: 1353 NDQTYNTKCVEENVFNVTINSNEHISFYLSKWIIEDNNTSYYINDSLIKNMNIVFLKIKN 1412

Query: 373  NAFMALTKPHWIEARETLQKLLDVSSPALQNNAELREKAFVK-QTDVQMHVP 525
            +     T     + +   + ++ +    ++NN    EK  +K   ++ M++P
Sbjct: 1413 DISQNYTNR---KRKNFFEDIVCMEKKYIENNKNNNEKMNIKVDININMNMP 1461


>UniRef50_O01603 Cluster: Putative uncharacterized protein; n=2;
           Caenorhabditis|Rep: Putative uncharacterized protein -
           Caenorhabditis elegans
          Length = 583

 Score = 33.5 bits (73), Expect = 7.8
 Identities = 35/136 (25%), Positives = 57/136 (41%), Gaps = 4/136 (2%)
 Frame = +1

Query: 148 CVKS*RKMKSFIEYSSDSDFPIENLPYGVFTSDKNAQKHIGVAIGEWILDLNIISRLFDG 327
           C       K+ IE+  D D     + + VF + K  +    + +GE + DLN+I    + 
Sbjct: 198 CSTGGEDQKNRIEWKVDGDL----IYFSVFQNAKKGRWWTAIGVGESMNDLNMILLFAEN 253

Query: 328 PLLKSKQNVFKEEKLNAFMALTKPHWIEARETLQKLLDVSSPALQNNAELREKAFVKQTD 507
             LK KQ +FK E       L   +  E  E  + L  V++     +  + +K F+ + D
Sbjct: 254 GRLK-KQGIFKTE--GKMQPLEVEY--EGIEVKKDLAIVNNGKANFDVSVEKKFFLDRAD 308

Query: 508 VQ----MHVPVEVGDY 543
            Q    M V +  G Y
Sbjct: 309 EQGCFTMQVAILAGQY 324


  Database: uniref50
    Posted date:  Oct 5, 2007 11:19 AM
  Number of letters in database: 575,637,011
  Number of sequences in database:  1,657,284
  
Lambda     K      H
   0.318    0.134    0.401 

Gapped
Lambda     K      H
   0.279   0.0580    0.190 


Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 910,210,303
Number of Sequences: 1657284
Number of extensions: 19450783
Number of successful extensions: 46533
Number of sequences better than 10.0: 34
Number of HSP's better than 10.0 without gapping: 44534
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 46472
length of database: 575,637,011
effective HSP length: 100
effective length of database: 409,908,611
effective search space used: 84851082477
frameshift window, decay const: 40,  0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)

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