Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= MFBP01_F_D08
(1013 letters)
Database: uniref50
1,657,284 sequences; 575,637,011 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
UniRef50_Q9Y020 Cluster: 3-dehydroecdysone 3beta-reductase precu... 153 5e-36
UniRef50_Q8WRT0 Cluster: 3-dehydrecdysone 3b-reductase; n=1; Tri... 149 9e-35
UniRef50_UPI00015B56A2 Cluster: PREDICTED: similar to GA10458-PA... 139 1e-31
UniRef50_UPI00015B56A3 Cluster: PREDICTED: similar to aldo-keto ... 133 6e-30
UniRef50_A3U9Y0 Cluster: Aldehyde reductase; n=5; Bacteroidetes|... 129 1e-28
UniRef50_Q8VC28 Cluster: Aldo-keto reductase family 1 member C13... 124 3e-27
UniRef50_Q7JVH6 Cluster: LD24696p; n=2; Sophophora|Rep: LD24696p... 123 6e-27
UniRef50_Q54B70 Cluster: Aldehyde reductase; n=2; Dictyostelium ... 122 1e-26
UniRef50_Q2LZ66 Cluster: GA19341-PA; n=2; Endopterygota|Rep: GA1... 122 1e-26
UniRef50_A5E082 Cluster: GCY protein; n=4; Saccharomycetales|Rep... 120 8e-26
UniRef50_Q41399 Cluster: Chalcone reductase; n=4; eudicotyledons... 118 3e-25
UniRef50_Q96UH3 Cluster: Aldehyde reductase; n=13; Pezizomycotin... 117 6e-25
UniRef50_Q7PCV3 Cluster: ENSANGP00000031808; n=9; Endopterygota|... 116 7e-25
UniRef50_Q9VTL0 Cluster: CG6083-PA; n=4; Diptera|Rep: CG6083-PA ... 115 2e-24
UniRef50_UPI0000588153 Cluster: PREDICTED: hypothetical protein;... 114 3e-24
UniRef50_Q5FK98 Cluster: Oxidoreductase; n=8; Lactobacillales|Re... 113 5e-24
UniRef50_Q6TY50 Cluster: Reductase 2; n=10; Magnoliophyta|Rep: R... 113 5e-24
UniRef50_Q2UGR1 Cluster: Aldo/keto reductase family proteins; n=... 113 5e-24
UniRef50_Q88SL1 Cluster: Oxidoreductase; n=51; Lactobacillales|R... 113 7e-24
UniRef50_Q8K023 Cluster: Aldo-keto reductase family 1 member C18... 112 2e-23
UniRef50_Q0VGY1 Cluster: 3-alpha-hydroxysteroid dehydrogenase; n... 110 5e-23
UniRef50_Q17DN0 Cluster: Aldo-keto reductase; n=5; Culicidae|Rep... 110 5e-23
UniRef50_UPI000023D0F1 Cluster: hypothetical protein FG03517.1; ... 110 6e-23
UniRef50_Q1YPE5 Cluster: Aldehyde reductase; n=7; Bacteria|Rep: ... 110 6e-23
UniRef50_A2EYY6 Cluster: Oxidoreductase, aldo/keto reductase fam... 109 8e-23
UniRef50_P14550 Cluster: Alcohol dehydrogenase [NADP+]; n=44; Bi... 108 2e-22
UniRef50_A7CUW0 Cluster: 2,5-didehydrogluconate reductase; n=6; ... 108 3e-22
UniRef50_Q8CI22 Cluster: 2310005E10Rik protein; n=30; Tetrapoda|... 107 3e-22
UniRef50_A2R6Z3 Cluster: Catalytic activity: an alcohol + NADP(+... 107 4e-22
UniRef50_Q7QK25 Cluster: ENSANGP00000019775; n=2; Anopheles gamb... 107 6e-22
UniRef50_Q23320 Cluster: Putative uncharacterized protein; n=4; ... 107 6e-22
UniRef50_P26690 Cluster: NAD(P)H-dependent 6'-deoxychalcone synt... 107 6e-22
UniRef50_UPI000065D0BD Cluster: Homolog of Homo sapiens "AKR1B1 ... 101 7e-22
UniRef50_Q8SSK6 Cluster: ALDOSE REDUCTASE; n=1; Encephalitozoon ... 106 1e-21
UniRef50_P06632 Cluster: 2,5-diketo-D-gluconic acid reductase A;... 106 1e-21
UniRef50_Q5BKE9 Cluster: LOC594893 protein; n=5; Xenopus tropica... 105 1e-21
UniRef50_Q2S340 Cluster: Aldehyde reductase; n=10; Bacteria|Rep:... 105 2e-21
UniRef50_Q01J82 Cluster: OSIGBa0152K17.5 protein; n=28; Magnolio... 105 2e-21
UniRef50_A6RKL9 Cluster: Putative uncharacterized protein; n=3; ... 105 2e-21
UniRef50_P15121 Cluster: Aldose reductase; n=72; Eumetazoa|Rep: ... 105 2e-21
UniRef50_P14065 Cluster: Protein GCY; n=13; Saccharomycetales|Re... 105 2e-21
UniRef50_A7BA05 Cluster: Putative uncharacterized protein; n=1; ... 104 3e-21
UniRef50_A7SIT3 Cluster: Predicted protein; n=1; Nematostella ve... 104 3e-21
UniRef50_P45376 Cluster: Aldose reductase; n=21; Bilateria|Rep: ... 104 3e-21
UniRef50_Q6CFG7 Cluster: Yarrowia lipolytica chromosome B of str... 103 6e-21
UniRef50_P27800 Cluster: Aldehyde reductase 1; n=18; root|Rep: A... 103 6e-21
UniRef50_UPI00015B40FA Cluster: PREDICTED: similar to CG2767-PA;... 103 7e-21
UniRef50_Q55FL3 Cluster: Aldo-keto reductase; n=2; Dictyostelium... 103 7e-21
UniRef50_Q9NAI5 Cluster: Putative uncharacterized protein; n=3; ... 102 1e-20
UniRef50_Q968S3 Cluster: Aldoketoreductase-like protein; n=1; Or... 101 2e-20
UniRef50_A2QBD7 Cluster: Catalytic activity: an alcohol + NADP(+... 101 2e-20
UniRef50_P28475 Cluster: NADP-dependent D-sorbitol-6-phosphate d... 101 3e-20
UniRef50_Q96JD6 Cluster: Aldo-keto reductase family 1 member C-l... 95 3e-20
UniRef50_Q96JD6-2 Cluster: Isoform 2 of Q96JD6 ; n=4; Catarrhini... 95 3e-20
UniRef50_UPI00015B4B22 Cluster: PREDICTED: similar to GA15457-PA... 101 4e-20
UniRef50_Q7WSY4 Cluster: Putative aldo-keto reductase; n=1; Prop... 101 4e-20
UniRef50_Q1U9L6 Cluster: 2,5-didehydrogluconate reductase; n=3; ... 101 4e-20
UniRef50_Q03TW0 Cluster: Aldo/keto reductase of diketogulonate r... 101 4e-20
UniRef50_A5KSS3 Cluster: Aldehyde reductase; n=1; candidate divi... 101 4e-20
UniRef50_Q5KI95 Cluster: Aldo-keto reductase, putative; n=14; Di... 101 4e-20
UniRef50_Q7QVQ9 Cluster: GLP_302_44328_45269; n=1; Giardia lambl... 100 5e-20
UniRef50_Q5T2L2 Cluster: Aldo-keto reductase family 1 member C-l... 100 5e-20
UniRef50_A3LTU8 Cluster: D-arabinose dehydrogenase; n=5; Sacchar... 100 7e-20
UniRef50_Q7G764 Cluster: Probable NAD(P)H-dependent oxidoreducta... 100 7e-20
UniRef50_Q9ZUJ6 Cluster: T2K10.1 protein; n=16; core eudicotyled... 99 9e-20
UniRef50_P23901 Cluster: Aldose reductase; n=9; Poaceae|Rep: Ald... 100 1e-19
UniRef50_P22045 Cluster: Probable reductase; n=101; cellular org... 99 2e-19
UniRef50_Q0IBY6 Cluster: Alcohol dehydrogenase; n=2; Chroococcal... 99 2e-19
UniRef50_Q2V420 Cluster: Uncharacterized protein At2g37770.1; n=... 99 2e-19
UniRef50_Q0PGJ6 Cluster: Aldo-keto reductase; n=32; Magnoliophyt... 99 2e-19
UniRef50_UPI0000498F1F Cluster: oxidoreductase, aldo/keto reduct... 98 3e-19
UniRef50_Q7PLK6 Cluster: CG40064-PA; n=1; Drosophila melanogaste... 98 3e-19
UniRef50_Q9HGY0 Cluster: Glycerol dehydrogenase; n=8; Saccharomy... 98 4e-19
UniRef50_Q83N50 Cluster: 2,5-diketo-D-gluconic acid reductase; n... 97 5e-19
UniRef50_Q9ZBW7 Cluster: Putative oxidoreductase; n=2; Actinomyc... 97 8e-19
UniRef50_A1UEC5 Cluster: 2,5-didehydrogluconate reductase; n=20;... 97 8e-19
UniRef50_A4RQH8 Cluster: Predicted protein; n=2; Ostreococcus|Re... 97 8e-19
UniRef50_Q6RZX1 Cluster: Gld1; n=22; Pezizomycotina|Rep: Gld1 - ... 97 8e-19
UniRef50_A7CWF9 Cluster: Aldehyde reductase; n=2; Bacteria|Rep: ... 96 1e-18
UniRef50_A3C1Z7 Cluster: Putative uncharacterized protein; n=2; ... 96 1e-18
UniRef50_Q16K66 Cluster: Aldo-keto reductase; n=2; Aedes aegypti... 96 1e-18
UniRef50_Q8F1G4 Cluster: Aldehyde reductase; n=8; Bacteria|Rep: ... 96 1e-18
UniRef50_A2FPE2 Cluster: Oxidoreductase, aldo/keto reductase fam... 96 1e-18
UniRef50_Q7ZA52 Cluster: Aldose reductase; n=6; Pezizomycotina|R... 96 1e-18
UniRef50_A1D4E3 Cluster: D-xylose reductase (Xyl1), putative; n=... 96 1e-18
UniRef50_UPI0000E45E29 Cluster: PREDICTED: similar to aldose red... 95 3e-18
UniRef50_P51857 Cluster: 3-oxo-5-beta-steroid 4-dehydrogenase (E... 95 3e-18
UniRef50_Q8ET73 Cluster: 2,5-diketo-D-gluconate reductase; n=12;... 94 4e-18
UniRef50_Q68ST9 Cluster: Reductase AKOR2; n=2; Pleurotus djamor|... 94 4e-18
UniRef50_A2QVE5 Cluster: Similarity: shows similarity to several... 94 4e-18
UniRef50_Q01HB5 Cluster: OSIGBa0136O08-OSIGBa0153H12.9 protein; ... 94 6e-18
UniRef50_Q10494 Cluster: Probable oxidoreductase C26F1.07; n=2; ... 94 6e-18
UniRef50_Q7ZWA4 Cluster: Zgc:56622; n=6; cellular organisms|Rep:... 93 8e-18
UniRef50_UPI000155CAC7 Cluster: PREDICTED: hypothetical protein;... 93 1e-17
UniRef50_A0JRJ3 Cluster: 2,5-didehydrogluconate reductase; n=3; ... 93 1e-17
UniRef50_Q890A0 Cluster: Oxidoreductase; n=6; Lactobacillales|Re... 93 1e-17
UniRef50_Q9VHX4 Cluster: CG2767-PA; n=4; Endopterygota|Rep: CG27... 93 1e-17
UniRef50_Q4PAT5 Cluster: Putative uncharacterized protein; n=1; ... 93 1e-17
UniRef50_Q03PG5 Cluster: Aldo/keto reductase of diketogulonate r... 92 2e-17
UniRef50_Q568D7 Cluster: Zgc:110366; n=7; Euteleostomi|Rep: Zgc:... 92 2e-17
UniRef50_Q4JX70 Cluster: Putative oxidoreductase; n=1; Corynebac... 92 2e-17
UniRef50_A2EHN6 Cluster: Oxidoreductase, aldo/keto reductase fam... 92 2e-17
UniRef50_A4FEB9 Cluster: 2,5-diketo-D-gluconic acid reductase; n... 91 3e-17
UniRef50_Q7G765 Cluster: Probable NAD(P)H-dependent oxidoreducta... 91 3e-17
UniRef50_Q8ZI40 Cluster: 2,5-diketo-D-gluconic acid reductase A;... 91 3e-17
UniRef50_Q5HR31 Cluster: Oxidoreductase, aldo/keto reductase fam... 91 4e-17
UniRef50_Q6NII7 Cluster: Putative oxidoreductase; n=2; Corynebac... 91 6e-17
UniRef50_Q7XY49 Cluster: Mannose 6-phosphate reductase; n=1; Gri... 91 6e-17
UniRef50_Q6C2L0 Cluster: Yarrowia lipolytica chromosome F of str... 91 6e-17
UniRef50_Q8J0K1 Cluster: 4-dihydromethyltrisporate dehydrogenase... 90 7e-17
UniRef50_Q9FJK0 Cluster: Aldose reductase-like protein; n=3; cor... 90 1e-16
UniRef50_Q8G7K9 Cluster: Dehydrogenase or reductase protein; n=4... 89 1e-16
UniRef50_Q0CLQ2 Cluster: Putative uncharacterized protein; n=1; ... 89 1e-16
UniRef50_UPI0000E4A7CE Cluster: PREDICTED: similar to LOC553452 ... 89 2e-16
UniRef50_Q9U2J5 Cluster: Putative uncharacterized protein; n=2; ... 89 2e-16
UniRef50_Q4Q5N9 Cluster: Prostaglandin f synthase, putative; n=7... 89 2e-16
UniRef50_P38115 Cluster: D-arabinose dehydrogenase [NAD(P)+] hea... 88 3e-16
UniRef50_Q5TNP1 Cluster: ENSANGP00000029046; n=2; Culicidae|Rep:... 88 4e-16
UniRef50_Q7N0E4 Cluster: 2,5-diketo-D-gluconic acid reductase A;... 87 5e-16
UniRef50_A6ESC0 Cluster: ARA1; n=1; unidentified eubacterium SCB... 87 5e-16
UniRef50_Q9X0A2 Cluster: Oxidoreductase, aldo/keto reductase fam... 87 7e-16
UniRef50_Q1VRG6 Cluster: YvgN; n=1; Psychroflexus torquis ATCC 7... 87 7e-16
UniRef50_Q1IN88 Cluster: Aldehyde reductase; n=5; Bacteria|Rep: ... 87 7e-16
UniRef50_A6W8E7 Cluster: 2,5-didehydrogluconate reductase; n=3; ... 87 7e-16
UniRef50_A7PNI3 Cluster: Chromosome chr1 scaffold_22, whole geno... 87 7e-16
UniRef50_Q22352 Cluster: Putative uncharacterized protein T08H10... 87 7e-16
UniRef50_Q03XK0 Cluster: Aldo/keto reductase of diketogulonate r... 87 9e-16
UniRef50_A5PDA8 Cluster: Putative oxidoreductase protein; n=1; E... 87 9e-16
UniRef50_Q7R2T6 Cluster: GLP_291_56367_57278; n=1; Giardia lambl... 87 9e-16
UniRef50_Q24C22 Cluster: Oxidoreductase, aldo/keto reductase fam... 86 1e-15
UniRef50_Q4PDR0 Cluster: Putative uncharacterized protein; n=1; ... 86 1e-15
UniRef50_P15339 Cluster: 2,5-diketo-D-gluconic acid reductase B;... 86 1e-15
UniRef50_Q41E86 Cluster: 2,5-didehydrogluconate reductase; n=2; ... 86 2e-15
UniRef50_Q4P4P1 Cluster: Putative uncharacterized protein; n=1; ... 86 2e-15
UniRef50_P38715 Cluster: NADPH-dependent aldose reductase GRE3; ... 86 2e-15
UniRef50_UPI0000519CC2 Cluster: PREDICTED: similar to CG2767-PA;... 85 2e-15
UniRef50_P47137 Cluster: Probable oxidoreductase YJR096W; n=8; S... 85 2e-15
UniRef50_UPI0000D9A956 Cluster: PREDICTED: similar to aldo-keto ... 85 3e-15
UniRef50_UPI00015B4912 Cluster: PREDICTED: similar to aldo-keto ... 84 5e-15
UniRef50_Q88TV9 Cluster: Oxidoreductase; n=4; Lactobacillus|Rep:... 84 6e-15
UniRef50_Q28P63 Cluster: Aldo/keto reductase; n=4; Rhodobacterac... 84 6e-15
UniRef50_Q5BLA6 Cluster: Zgc:110782; n=2; Danio rerio|Rep: Zgc:1... 83 8e-15
UniRef50_Q1Q8W8 Cluster: Aldo/keto reductase; n=1; Psychrobacter... 83 8e-15
UniRef50_P70883 Cluster: AkrI; n=1; Butyrivibrio fibrisolvens|Re... 83 8e-15
UniRef50_Q4FY75 Cluster: Aldo-keto reductase-like protein; n=5; ... 83 1e-14
UniRef50_UPI0000DB6EE9 Cluster: PREDICTED: similar to C35D10.6; ... 83 1e-14
UniRef50_A6WDZ5 Cluster: Aldo/keto reductase; n=5; Bacteria|Rep:... 82 3e-14
UniRef50_Q9P6D3 Cluster: Related to aldo-keto reductase YPR1; n=... 82 3e-14
UniRef50_UPI00006CCCD7 Cluster: oxidoreductase, aldo/keto reduct... 81 3e-14
UniRef50_Q6F7K7 Cluster: 2,5-diketo-D-gluconate reductase; n=20;... 81 3e-14
UniRef50_A2UAH0 Cluster: Aldo/keto reductase; n=1; Bacillus coag... 81 3e-14
UniRef50_A0JX62 Cluster: 2,5-didehydrogluconate reductase; n=9; ... 81 3e-14
UniRef50_A0AWM8 Cluster: Aldo/keto reductase; n=4; Actinomycetal... 81 3e-14
UniRef50_Q235V6 Cluster: Oxidoreductase, aldo/keto reductase fam... 81 3e-14
UniRef50_Q927P9 Cluster: Lin2739 protein; n=12; Bacteria|Rep: Li... 81 4e-14
UniRef50_Q9X265 Cluster: Oxidoreductase, aldo/keto reductase fam... 81 6e-14
UniRef50_Q0SFM4 Cluster: Probable 2,5-didehydrogluconate reducta... 81 6e-14
UniRef50_A3VHZ9 Cluster: Oxidoreductase; n=1; Rhodobacterales ba... 81 6e-14
UniRef50_A0JRJ6 Cluster: Aldo/keto reductase; n=2; Micrococcinea... 81 6e-14
UniRef50_Q8ZH36 Cluster: 2,5-diketo-D-gluconic acid reductase B;... 81 6e-14
UniRef50_Q8Y463 Cluster: Lmo2592 protein; n=40; Bacteria|Rep: Lm... 80 8e-14
UniRef50_Q838E0 Cluster: Oxidoreductase, aldo/keto reductase fam... 80 8e-14
UniRef50_Q05KR9 Cluster: Benzil reductase; n=5; Bacillales|Rep: ... 80 8e-14
UniRef50_Q18483 Cluster: Putative uncharacterized protein; n=2; ... 80 8e-14
UniRef50_Q89JN4 Cluster: Oxidoreductase; n=8; Rhizobiales|Rep: O... 80 1e-13
UniRef50_A5ZYE6 Cluster: Putative uncharacterized protein; n=1; ... 79 1e-13
UniRef50_UPI00006CD296 Cluster: oxidoreductase, aldo/keto reduct... 79 2e-13
UniRef50_Q9HM42 Cluster: Alcohol dehydrogenase related protein; ... 79 2e-13
UniRef50_Q02198 Cluster: Morphine 6-dehydrogenase; n=5; Bacteria... 79 2e-13
UniRef50_Q1M4Z6 Cluster: Putative aldo-keto reductase/oxidase; n... 78 3e-13
UniRef50_A5VK30 Cluster: 2,5-didehydrogluconate reductase; n=2; ... 78 3e-13
UniRef50_A7P424 Cluster: Chromosome chr1 scaffold_5, whole genom... 78 3e-13
UniRef50_Q76L37 Cluster: Conjugated polyketone reductase C1; n=3... 78 3e-13
UniRef50_Q0CK00 Cluster: Predicted protein; n=1; Aspergillus ter... 78 3e-13
UniRef50_Q7VG53 Cluster: Aldo-keto reductase; n=28; Bacteria|Rep... 78 4e-13
UniRef50_Q4V008 Cluster: Oxidoreductase; n=4; Proteobacteria|Rep... 78 4e-13
UniRef50_Q3CZS2 Cluster: Oxidoreductase, aldo/keto reductase fam... 78 4e-13
UniRef50_A3UJS6 Cluster: Oxidoreductase; n=3; Alphaproteobacteri... 78 4e-13
UniRef50_Q7PM68 Cluster: ENSANGP00000014386; n=1; Anopheles gamb... 78 4e-13
UniRef50_A2QL02 Cluster: Putative frameshift; n=1; Aspergillus n... 78 4e-13
UniRef50_Q6U5V3 Cluster: Putative uncharacterized protein; n=1; ... 77 6e-13
UniRef50_A6NPD6 Cluster: Putative uncharacterized protein; n=3; ... 77 6e-13
UniRef50_A7RRF6 Cluster: Predicted protein; n=2; Nematostella ve... 77 6e-13
UniRef50_UPI0000499B0E Cluster: oxidoreductase, aldo/keto reduct... 77 7e-13
UniRef50_Q14LU6 Cluster: Putative aldo/keto reductase oxidoreduc... 77 7e-13
UniRef50_Q572D2 Cluster: Aldo-keto reductase, putative; n=1; Phy... 77 7e-13
UniRef50_UPI00015B5BD7 Cluster: PREDICTED: similar to aldo-keto ... 77 1e-12
UniRef50_Q5FKI1 Cluster: Reductase-dehydrogenase; n=1; Lactobaci... 77 1e-12
UniRef50_Q3E9M9 Cluster: Uncharacterized protein At5g01670.2; n=... 77 1e-12
UniRef50_Q5B5R6 Cluster: Putative uncharacterized protein; n=1; ... 77 1e-12
UniRef50_Q9A2X8 Cluster: Oxidoreductase, aldo/keto reductase fam... 76 2e-12
UniRef50_Q979I4 Cluster: Aldo / keto reductase; n=3; Archaea|Rep... 76 2e-12
UniRef50_Q5UX52 Cluster: Oxidoreductase aldo/keto reductase fami... 76 2e-12
UniRef50_Q2CAL9 Cluster: 2,5-didehydrogluconate reductase; n=2; ... 75 2e-12
UniRef50_Q1RFP0 Cluster: 2,5-diketo-D-gluconic acid reductase A;... 75 2e-12
UniRef50_A7ALH6 Cluster: Putative uncharacterized protein; n=1; ... 75 2e-12
UniRef50_A0L1A2 Cluster: Aldo/keto reductase; n=8; Gammaproteoba... 75 2e-12
UniRef50_Q7NB44 Cluster: ARA1; n=3; Firmicutes|Rep: ARA1 - Mycop... 75 3e-12
UniRef50_Q1PV10 Cluster: Putative uncharacterized protein; n=1; ... 75 3e-12
UniRef50_Q03U37 Cluster: Aldo/keto reductase of diketogulonate r... 75 3e-12
UniRef50_Q15NA5 Cluster: Aldo/keto reductase; n=2; Gammaproteoba... 75 4e-12
UniRef50_Q043M4 Cluster: Aldo/keto reductase of diketogulonate r... 75 4e-12
UniRef50_O13848 Cluster: NADH/NADPH dependent indole-3-acetaldeh... 75 4e-12
UniRef50_Q5V663 Cluster: Aldehyde reductase; n=6; Halobacteriace... 75 4e-12
UniRef50_Q5XJM7 Cluster: Zgc:101765; n=5; Eumetazoa|Rep: Zgc:101... 74 7e-12
UniRef50_Q11DV1 Cluster: Aldo/keto reductase; n=10; Alphaproteob... 74 7e-12
UniRef50_Q03BE0 Cluster: Aldo/keto reductase family enzyme; n=5;... 74 7e-12
UniRef50_A6LZ55 Cluster: 2,5-didehydrogluconate reductase; n=1; ... 74 7e-12
UniRef50_Q6CEJ0 Cluster: Yarrowia lipolytica chromosome B of str... 74 7e-12
UniRef50_Q4PHK0 Cluster: Putative uncharacterized protein; n=1; ... 74 7e-12
UniRef50_Q929C8 Cluster: Lin2349 protein; n=12; Listeria|Rep: Li... 73 9e-12
UniRef50_A4YQ04 Cluster: 2,5-diketo-D-gluconate reductase B; n=1... 73 9e-12
UniRef50_A1RB46 Cluster: 2,5-diketo-D-gluconate reductase; n=1; ... 73 9e-12
UniRef50_Q927E1 Cluster: Lin2848 protein; n=13; Listeria|Rep: Li... 73 1e-11
UniRef50_Q54NR2 Cluster: Aldo-keto reductase; n=3; Dictyostelium... 73 2e-11
UniRef50_A7D6Q0 Cluster: Aldo/keto reductase; n=1; Halorubrum la... 73 2e-11
UniRef50_A3VRL4 Cluster: Putative uncharacterized protein; n=1; ... 72 2e-11
UniRef50_Q76L36 Cluster: Conjugated polyketone reductase C2; n=1... 72 2e-11
UniRef50_A6VNW9 Cluster: Aldo/keto reductase precursor; n=1; Act... 72 3e-11
UniRef50_Q17G72 Cluster: Aldo-keto reductase; n=9; Endopterygota... 72 3e-11
UniRef50_Q03X85 Cluster: Aldo/keto reductase of diketogulonate r... 71 4e-11
UniRef50_Q5K8C5 Cluster: Aldo-keto reductase, putative; n=1; Fil... 71 4e-11
UniRef50_Q5FK99 Cluster: Oxidoreductase aldo-keto reductase fami... 71 6e-11
UniRef50_A7BES9 Cluster: Putative uncharacterized protein; n=1; ... 71 6e-11
UniRef50_Q2U219 Cluster: Aldo/keto reductase family proteins; n=... 71 6e-11
UniRef50_Q5V398 Cluster: Oxidoreductase aldo/keto reductase fami... 71 6e-11
UniRef50_Q5UYI9 Cluster: Oxidoreductase; n=1; Haloarcula marismo... 71 6e-11
UniRef50_Q5V6N9 Cluster: Alcohol dehydrogenase; n=2; Halobacteri... 70 8e-11
UniRef50_UPI00006CA3CB Cluster: oxidoreductase, aldo/keto reduct... 70 1e-10
UniRef50_Q11B35 Cluster: Aldo/keto reductase; n=1; Mesorhizobium... 70 1e-10
UniRef50_Q7VHE1 Cluster: Putative uncharacterized protein; n=1; ... 69 1e-10
UniRef50_Q5FT75 Cluster: Putative 2,5-diketo-D-gluconic acid red... 69 1e-10
UniRef50_Q11BF8 Cluster: Aldo/keto reductase; n=12; Bacteria|Rep... 69 2e-10
UniRef50_A2RMU6 Cluster: Oxidoreductase, aldo/keto reductase fam... 69 2e-10
UniRef50_Q4JCC1 Cluster: 2,5-diketo-D-gluconic acid reductase A;... 69 2e-10
UniRef50_A3LWP0 Cluster: Aldo/keto reductase; n=7; Saccharomycet... 69 3e-10
UniRef50_A3JU52 Cluster: 2,5-diketo-D-gluconic acid reductase A;... 68 3e-10
UniRef50_Q97U17 Cluster: Oxidoreductase, aldo/keto reductase fam... 68 3e-10
UniRef50_Q14LA8 Cluster: Putative aldo/keto reductase oxidoreduc... 68 4e-10
UniRef50_Q6CWB9 Cluster: Similarities with sp|Q12458 Saccharomyc... 68 4e-10
UniRef50_Q5FLI5 Cluster: Aldehyde reductase; n=2; Bacteria|Rep: ... 67 6e-10
UniRef50_A7SGW6 Cluster: Predicted protein; n=1; Nematostella ve... 67 6e-10
UniRef50_A4IJ00 Cluster: LOC548351 protein; n=1; Xenopus tropica... 67 8e-10
UniRef50_A3T261 Cluster: Putative uncharacterized protein; n=1; ... 67 8e-10
UniRef50_Q75E75 Cluster: ABL209Cp; n=1; Eremothecium gossypii|Re... 67 8e-10
UniRef50_Q97UV9 Cluster: Oxidoreductase; n=1; Sulfolobus solfata... 67 8e-10
UniRef50_Q8EUH6 Cluster: Oxidoreductase; n=1; Mycoplasma penetra... 66 1e-09
UniRef50_Q16CS5 Cluster: 2,5-diketo-D-gluconic acid reductase B,... 66 1e-09
UniRef50_A6PR52 Cluster: Aldo/keto reductase; n=1; Victivallis v... 66 1e-09
UniRef50_Q17DN1 Cluster: Aldo-keto reductase; n=1; Aedes aegypti... 66 1e-09
UniRef50_Q4WI64 Cluster: Aldehyde reductase, putative; n=22; Pez... 66 1e-09
UniRef50_Q9V2P1 Cluster: Myo-inositol degradation; n=5; Archaea|... 66 1e-09
UniRef50_A2G4I3 Cluster: Oxidoreductase, aldo/keto reductase fam... 66 2e-09
UniRef50_P91997 Cluster: Putative uncharacterized protein; n=4; ... 65 2e-09
UniRef50_Q4P1G1 Cluster: Putative uncharacterized protein; n=1; ... 65 2e-09
UniRef50_A5AD50 Cluster: Putative uncharacterized protein; n=3; ... 65 3e-09
UniRef50_Q5KD52 Cluster: Oxidoreductase, putative; n=1; Filobasi... 65 3e-09
UniRef50_Q4WUF7 Cluster: Aldo-keto reductase, putative; n=3; Pez... 65 3e-09
UniRef50_A7D761 Cluster: Aldo/keto reductase; n=2; Halobacteriac... 64 4e-09
UniRef50_A7D7K7 Cluster: Aldo/keto reductase; n=1; Halorubrum la... 64 5e-09
UniRef50_Q8EVS8 Cluster: Oxidoreductase; n=1; Mycoplasma penetra... 64 7e-09
UniRef50_Q09632 Cluster: Probable oxidoreductase ZK1290.5; n=2; ... 64 7e-09
UniRef50_A3WP89 Cluster: Aldo/keto reductase; n=1; Idiomarina ba... 63 1e-08
UniRef50_Q5KKZ8 Cluster: Aldo-keto reductase, putative; n=2; Fil... 63 1e-08
UniRef50_Q8DK16 Cluster: Tlr1054 protein; n=6; Cyanobacteria|Rep... 63 1e-08
UniRef50_Q4WP69 Cluster: Aldehyde reductase, putative; n=1; Aspe... 63 1e-08
UniRef50_A2QB88 Cluster: Contig An01c0460, complete genome. prec... 63 1e-08
UniRef50_Q59Z55 Cluster: Potential aldo/keto reductase; n=6; Sac... 62 2e-08
UniRef50_P76234 Cluster: Uncharacterized protein yeaE; n=39; Bac... 62 2e-08
UniRef50_Q4DJ59 Cluster: Aldo/keto reductase, putative; n=2; Try... 61 4e-08
UniRef50_Q2H7A8 Cluster: Putative uncharacterized protein; n=1; ... 61 4e-08
UniRef50_A6QVW8 Cluster: Predicted protein; n=1; Ajellomyces cap... 61 4e-08
UniRef50_Q9P734 Cluster: Related to 2, 5-diketo-D-gluconic acid ... 61 5e-08
UniRef50_Q1DLF1 Cluster: Putative uncharacterized protein; n=1; ... 61 5e-08
UniRef50_O14088 Cluster: Xylose and arabinose reductase; n=1; Sc... 61 5e-08
UniRef50_Q21274 Cluster: Putative uncharacterized protein; n=1; ... 60 7e-08
UniRef50_A1CAM7 Cluster: Aldo-keto reductase, putative; n=9; Dik... 60 7e-08
UniRef50_A7RUA2 Cluster: Predicted protein; n=1; Nematostella ve... 60 9e-08
UniRef50_Q2BBN7 Cluster: YvgN; n=1; Bacillus sp. NRRL B-14911|Re... 59 2e-07
UniRef50_Q1EZH4 Cluster: Aldo/keto reductase:4Fe-4S ferredoxin, ... 59 2e-07
UniRef50_A7TLC4 Cluster: Putative uncharacterized protein; n=1; ... 59 2e-07
UniRef50_Q5V1M9 Cluster: Oxidoreductase aldo/keto reductase fami... 59 2e-07
UniRef50_Q4Q5X1 Cluster: Aldehyde reductase, putative; n=75; cel... 59 2e-07
UniRef50_Q59ZT1 Cluster: Putative uncharacterized protein; n=1; ... 59 2e-07
UniRef50_A4R217 Cluster: Putative uncharacterized protein; n=1; ... 59 2e-07
UniRef50_Q68A33 Cluster: Aldo-keto reductase 1a; n=1; Ciona inte... 58 3e-07
UniRef50_A5DRJ6 Cluster: Putative uncharacterized protein; n=4; ... 58 3e-07
UniRef50_A3DNU7 Cluster: Aldo/keto reductase; n=3; Desulfurococc... 58 3e-07
UniRef50_Q6L139 Cluster: 2,5-diketo-D-gluconic acid reductase; n... 58 4e-07
UniRef50_Q6WGK4 Cluster: Aldose reductase; n=1; Pristionchus pac... 58 5e-07
UniRef50_Q9C1X5 Cluster: Xylose and arabinose reductase; n=1; Sc... 58 5e-07
UniRef50_Q8EVT8 Cluster: Oxidoreductase-aldo/keto reductase fami... 57 6e-07
UniRef50_A3H9Y8 Cluster: Aldo/keto reductase; n=2; Caldivirga ma... 57 6e-07
UniRef50_Q0GU15 Cluster: ORF28; n=3; Bacteria|Rep: ORF28 - Lacto... 57 8e-07
UniRef50_Q97V56 Cluster: Dehydrogenase; n=8; Thermoprotei|Rep: D... 57 8e-07
UniRef50_Q7M4N1 Cluster: Dihydrodiol dehydrogenase DD2; n=2; Hom... 56 1e-06
UniRef50_Q5KKC5 Cluster: Putative uncharacterized protein; n=2; ... 56 1e-06
UniRef50_Q5KCN9 Cluster: Putative uncharacterized protein; n=1; ... 56 1e-06
UniRef50_A7D6I8 Cluster: Aldo/keto reductase; n=1; Halorubrum la... 56 1e-06
UniRef50_Q07551 Cluster: NADPH-dependent alpha-keto amide reduct... 56 1e-06
UniRef50_Q17568 Cluster: Putative uncharacterized protein; n=1; ... 56 2e-06
UniRef50_Q89RG2 Cluster: Aldo/keto reductase; n=11; Bacteria|Rep... 55 3e-06
UniRef50_Q5FHT2 Cluster: Aldehyde reductase; n=4; Lactobacillus|... 55 3e-06
UniRef50_A6SI80 Cluster: Putative uncharacterized protein; n=1; ... 55 3e-06
UniRef50_Q5NLW3 Cluster: Putative oxidoreductase; n=1; Zymomonas... 55 3e-06
UniRef50_Q00XM4 Cluster: Aldo/keto reductase family proteins; n=... 55 3e-06
UniRef50_Q55FL2 Cluster: Putative uncharacterized protein; n=1; ... 55 3e-06
UniRef50_A1CHK2 Cluster: Aldose 1-epimerase, putative; n=11; Pez... 55 3e-06
UniRef50_P82125 Cluster: 1,5-anhydro-D-fructose reductase; n=1; ... 55 3e-06
UniRef50_P91021 Cluster: Putative uncharacterized protein; n=1; ... 54 4e-06
UniRef50_P80874 Cluster: General stress protein 69; n=16; cellul... 54 4e-06
UniRef50_A5BF24 Cluster: Putative uncharacterized protein; n=1; ... 54 6e-06
UniRef50_Q61U89 Cluster: Putative uncharacterized protein CBG054... 54 6e-06
UniRef50_A6RMS0 Cluster: Putative uncharacterized protein; n=1; ... 54 6e-06
UniRef50_Q1IQ78 Cluster: Aldo/keto reductase; n=1; Acidobacteria... 54 8e-06
UniRef50_UPI000038E317 Cluster: hypothetical protein Faci_030017... 53 1e-05
UniRef50_Q8EUX1 Cluster: Aldo/keto reductase family oxidoreducta... 53 1e-05
UniRef50_Q4Q973 Cluster: Aldo/keto reductase, putative; n=3; Lei... 53 1e-05
UniRef50_Q5B034 Cluster: Putative uncharacterized protein; n=1; ... 53 1e-05
UniRef50_Q9W2X0 Cluster: CG32688-PA, isoform A; n=4; Sophophora|... 53 1e-05
UniRef50_UPI00005A2CCB Cluster: PREDICTED: similar to Aldose red... 52 2e-05
UniRef50_A6R5B4 Cluster: NAD(P)H-dependent D-xylose reductase; n... 52 2e-05
UniRef50_Q8ZU65 Cluster: Aldo-keto reductase, putative; n=4; The... 52 3e-05
UniRef50_Q8YXI8 Cluster: All1225 protein; n=9; Cyanobacteria|Rep... 51 4e-05
UniRef50_A2UBC7 Cluster: Aldo/keto reductase; n=3; cellular orga... 51 5e-05
UniRef50_Q55ML8 Cluster: Putative uncharacterized protein; n=2; ... 51 5e-05
UniRef50_A7EW94 Cluster: Putative uncharacterized protein; n=1; ... 51 5e-05
UniRef50_A5BYJ4 Cluster: Putative uncharacterized protein; n=1; ... 50 7e-05
UniRef50_UPI00015BB020 Cluster: aldo/keto reductase; n=1; Ignico... 50 1e-04
UniRef50_A0LJ47 Cluster: Aldo/keto reductase; n=1; Syntrophobact... 50 1e-04
UniRef50_Q5KPU6 Cluster: Putative uncharacterized protein; n=2; ... 50 1e-04
UniRef50_A6QXT4 Cluster: Predicted protein; n=1; Ajellomyces cap... 50 1e-04
UniRef50_Q97UJ7 Cluster: Oxidoreductase; n=4; Archaea|Rep: Oxido... 50 1e-04
UniRef50_UPI0000D56CE5 Cluster: PREDICTED: similar to CG6084-PA,... 50 1e-04
UniRef50_A7LSN6 Cluster: Putative uncharacterized protein; n=3; ... 50 1e-04
UniRef50_A1S0T5 Cluster: Aldo/keto reductase; n=2; Thermoprotei|... 50 1e-04
UniRef50_A7HL79 Cluster: Aldo/keto reductase; n=1; Fervidobacter... 49 2e-04
UniRef50_Q2NGB6 Cluster: Predicted oxidoreductase; n=1; Methanos... 49 2e-04
UniRef50_Q391C9 Cluster: Aldo/keto reductase; n=10; Proteobacter... 48 4e-04
UniRef50_Q21EY6 Cluster: Aldo/keto reductase; n=1; Saccharophagu... 48 4e-04
UniRef50_A7BLU0 Cluster: Aldo/keto reductase family; n=1; Beggia... 48 4e-04
UniRef50_A4M6J9 Cluster: Aldo/keto reductase; n=1; Petrotoga mob... 48 4e-04
UniRef50_Q88ZU3 Cluster: Oxidoreductase; n=1; Lactobacillus plan... 48 5e-04
UniRef50_Q7Q0Y6 Cluster: ENSANGP00000006086; n=7; Coelomata|Rep:... 47 7e-04
UniRef50_Q4PE96 Cluster: Putative uncharacterized protein; n=1; ... 47 7e-04
UniRef50_Q55493 Cluster: Auxin-induced protein; n=2; Bacteria|Re... 47 9e-04
UniRef50_Q38Z15 Cluster: Putative aldo/keto reductase; n=2; Bact... 47 9e-04
UniRef50_A0Q648 Cluster: Aldo/keto reductase family protein; n=1... 47 9e-04
UniRef50_Q46851 Cluster: Uncharacterized protein yghZ; n=126; Ba... 47 9e-04
UniRef50_Q9X0R5 Cluster: Oxidoreductase, aldo/keto reductase fam... 46 0.001
UniRef50_Q660Z5 Cluster: Aldose reductase, putative; n=3; Borrel... 46 0.001
UniRef50_A5V463 Cluster: Aldo/keto reductase; n=1; Sphingomonas ... 46 0.002
UniRef50_A5CYR4 Cluster: Predicted oxidoreductases; n=2; Clostri... 46 0.002
UniRef50_Q013C5 Cluster: Glycerol dehydrogenase, putative; n=2; ... 46 0.002
UniRef50_Q97ZZ1 Cluster: Oxidoreductase; n=4; Sulfolobaceae|Rep:... 46 0.002
UniRef50_Q97UG6 Cluster: Oxidoreductase; n=5; Archaea|Rep: Oxido... 46 0.002
UniRef50_Q04TM6 Cluster: Aryl-alcohol dehydrogenase-related oxid... 46 0.002
UniRef50_A1SLH1 Cluster: Aldo/keto reductase; n=27; Bacteria|Rep... 46 0.002
UniRef50_A0JVH3 Cluster: Aldo/keto reductase; n=17; Bacteria|Rep... 46 0.002
UniRef50_O43448 Cluster: Voltage-gated potassium channel subunit... 46 0.002
UniRef50_UPI000023DF27 Cluster: hypothetical protein FG07276.1; ... 45 0.003
UniRef50_Q7D3N9 Cluster: AGR_pAT_274p; n=3; Proteobacteria|Rep: ... 45 0.003
UniRef50_A6LWU9 Cluster: Aldo/keto reductase; n=3; Clostridium|R... 45 0.003
UniRef50_A6C9W8 Cluster: Aldo/keto reductase; n=2; Planctomyceta... 45 0.003
UniRef50_A6BIJ0 Cluster: Putative uncharacterized protein; n=1; ... 45 0.003
UniRef50_UPI00005F9591 Cluster: COG0656: Aldo/keto reductases, r... 45 0.004
UniRef50_Q7NK63 Cluster: Gll1617 protein; n=1; Gloeobacter viola... 45 0.004
UniRef50_Q5ZTU6 Cluster: D-xylose reductase III; n=5; Legionella... 45 0.004
UniRef50_Q3ZWR6 Cluster: Oxidoreductase, aldo reductase; n=3; De... 45 0.004
UniRef50_P73573 Cluster: Sll0867 protein; n=15; Bacteria|Rep: Sl... 45 0.004
UniRef50_A0K203 Cluster: Aldo/keto reductase; n=2; Arthrobacter|... 45 0.004
UniRef50_Q18903 Cluster: Putative uncharacterized protein C56G3.... 45 0.004
UniRef50_UPI0000DAE567 Cluster: hypothetical protein Rgryl_01000... 44 0.005
UniRef50_A7RXR1 Cluster: Predicted protein; n=3; Eumetazoa|Rep: ... 44 0.005
UniRef50_Q8PVL5 Cluster: Oxidoreductase, ALDO/KETO reductase fam... 44 0.005
UniRef50_Q4SFJ7 Cluster: Chromosome 7 SCAF14601, whole genome sh... 44 0.006
UniRef50_A6X3I0 Cluster: Aldo/keto reductase; n=3; Bacteria|Rep:... 44 0.006
UniRef50_Q4WF80 Cluster: Glycerol dehydrogenase (GCY1), putative... 44 0.006
UniRef50_Q8TTK4 Cluster: Aldo/keto reductase; n=28; cellular org... 44 0.006
UniRef50_Q8EVP7 Cluster: Putative oxidoreductase; n=3; Bacteria|... 44 0.008
UniRef50_A1SY15 Cluster: Aldo/keto reductase; n=1; Psychromonas ... 44 0.008
UniRef50_Q6CGE9 Cluster: Similar to sp|P47137 Saccharomyces cere... 44 0.008
UniRef50_Q1FEK2 Cluster: Aldo/keto reductase:4Fe-4S ferredoxin, ... 43 0.011
UniRef50_Q022Y6 Cluster: Aldo/keto reductase precursor; n=2; Sol... 43 0.011
UniRef50_Q9USV2 Cluster: Xylose and arabinose reductase; n=2; Sc... 43 0.011
UniRef50_P49261 Cluster: Rho beta-crystallin; n=1; Lepidodactylu... 43 0.011
UniRef50_Q8YAN3 Cluster: Lmo0084 protein; n=11; Listeria monocyt... 43 0.014
UniRef50_Q64W37 Cluster: 2,5-diketo-D-gluconic acid reductase; n... 43 0.014
UniRef50_Q64UK5 Cluster: Aldo/keto reductase family oxidoreducta... 43 0.014
UniRef50_Q8PN61 Cluster: Oxidoreductase; n=5; Proteobacteria|Rep... 42 0.019
UniRef50_Q88TP1 Cluster: Oxidoreductase; n=3; Bacteria|Rep: Oxid... 42 0.019
UniRef50_A6SUJ2 Cluster: Uncharacterized conserved protein; n=2;... 42 0.019
UniRef50_A7TT39 Cluster: Putative uncharacterized protein; n=1; ... 42 0.019
UniRef50_Q8R6G2 Cluster: Oxidoreductase; n=1; Fusobacterium nucl... 42 0.025
UniRef50_Q8F4Y9 Cluster: Aldo/keto reductase family protein; n=4... 42 0.025
UniRef50_A6C2P2 Cluster: Oxidoreductase, aldo/keto reductase fam... 42 0.025
UniRef50_A0LHW7 Cluster: Aldo/keto reductase precursor; n=1; Syn... 42 0.025
UniRef50_A0GAJ5 Cluster: Aldo/keto reductase precursor; n=9; Pro... 42 0.025
UniRef50_P46905 Cluster: Uncharacterized oxidoreductase yccK; n=... 42 0.025
UniRef50_UPI00015B403B Cluster: PREDICTED: similar to CG18547-PA... 42 0.033
UniRef50_Q8A955 Cluster: Aldo/keto reductase; n=8; Bacteroidales... 42 0.033
UniRef50_Q87SA8 Cluster: Oxidoreductase Tas, aldo/keto reductase... 42 0.033
UniRef50_A1ZPI5 Cluster: Oxidoreductase; n=1; Microscilla marina... 42 0.033
UniRef50_A1RJL6 Cluster: Aldo/keto reductase; n=37; Bacteria|Rep... 42 0.033
UniRef50_Q6NKP1 Cluster: At5g53580; n=18; cellular organisms|Rep... 42 0.033
UniRef50_Q94A68 Cluster: Uncharacterized oxidoreductase At1g0669... 42 0.033
UniRef50_UPI0000447325 Cluster: PREDICTED: similar to aldo-keto ... 41 0.044
UniRef50_Q8Y5Q1 Cluster: Lmo2005 protein; n=34; cellular organis... 41 0.044
UniRef50_Q2BBT9 Cluster: Probable oxidoreductase protein; n=2; B... 41 0.044
UniRef50_A7AFQ7 Cluster: Putative uncharacterized protein; n=1; ... 41 0.044
UniRef50_A6WAE5 Cluster: Aldo/keto reductase; n=1; Kineococcus r... 41 0.044
UniRef50_A6FYX9 Cluster: Oxidoreductase; n=1; Plesiocystis pacif... 41 0.044
UniRef50_A5VEK4 Cluster: Aldo/keto reductase; n=5; Bacteria|Rep:... 41 0.044
UniRef50_A5ZM37 Cluster: Putative uncharacterized protein; n=1; ... 41 0.058
UniRef50_Q011A7 Cluster: Putative aldo/keto reductase family pro... 41 0.058
UniRef50_UPI00003C85A8 Cluster: hypothetical protein Faci_030001... 40 0.077
UniRef50_Q0BAM8 Cluster: Aldo/keto reductase; n=1; Burkholderia ... 40 0.077
UniRef50_A0YC40 Cluster: Putative uncharacterized protein; n=1; ... 40 0.077
UniRef50_Q2NFN7 Cluster: Predicted oxidoreductase; n=1; Methanos... 40 0.077
UniRef50_Q3A7S5 Cluster: Predicted oxidoreductases of the aldo/k... 40 0.10
UniRef50_Q31SB1 Cluster: Putative uncharacterized protein; n=2; ... 40 0.10
UniRef50_Q1U6R9 Cluster: Aldo/keto reductase; n=25; Bacilli|Rep:... 40 0.10
UniRef50_Q11BU4 Cluster: Aldo/keto reductase; n=11; Proteobacter... 40 0.10
UniRef50_Q0SJ60 Cluster: Possible aldo/keto reductase; n=50; Bac... 40 0.10
UniRef50_A1SEE9 Cluster: Aldo/keto reductase; n=1; Nocardioides ... 40 0.10
UniRef50_A0YSM3 Cluster: Probable oxidoreductase; n=1; Lyngbya s... 40 0.10
UniRef50_Q9YBV5 Cluster: Putative uncharacterized protein; n=1; ... 40 0.10
UniRef50_Q93KW0 Cluster: Putative oxidoreductase; n=1; Streptomy... 40 0.13
UniRef50_Q3WEJ4 Cluster: Aldo/keto reductase; n=9; Bacteria|Rep:... 40 0.13
UniRef50_Q0LP88 Cluster: Aldo/keto reductase; n=4; Bacteria|Rep:... 40 0.13
UniRef50_Q097V7 Cluster: MocA; n=1; Stigmatella aurantiaca DW4/3... 40 0.13
UniRef50_A5EX65 Cluster: Aldo/keto reductase family protein; n=1... 40 0.13
UniRef50_Q5KYH6 Cluster: K+ channel beta subunit; n=5; Bacteria|... 39 0.18
UniRef50_Q0AQX2 Cluster: Aldo/keto reductase; n=1; Maricaulis ma... 39 0.18
UniRef50_Q3AEN5 Cluster: Oxidoreductase, aldo/keto reductase fam... 39 0.24
UniRef50_Q2J7H2 Cluster: Aldo/keto reductase; n=16; Bacteria|Rep... 39 0.24
UniRef50_Q1FGT1 Cluster: Aldo/keto reductase:4Fe-4S ferredoxin, ... 39 0.24
UniRef50_A7HEV1 Cluster: Aldo/keto reductase; n=13; Bacteria|Rep... 39 0.24
UniRef50_A7GIW7 Cluster: Oxidoreductase, aldo/keto reductase fam... 39 0.24
UniRef50_Q0UIH5 Cluster: Putative uncharacterized protein; n=1; ... 39 0.24
UniRef50_O59826 Cluster: Potassium channel subunit; n=9; cellula... 39 0.24
UniRef50_UPI0001556575 Cluster: PREDICTED: similar to Aldo-keto ... 38 0.31
UniRef50_Q97KZ9 Cluster: Fe-S oxidoreductase; n=6; cellular orga... 38 0.31
UniRef50_Q60BI7 Cluster: Oxidoreductase, aldo/keto reductase fam... 38 0.31
UniRef50_Q21F89 Cluster: Aldo/keto reductase; n=1; Saccharophagu... 38 0.31
UniRef50_A4MAE7 Cluster: Aldo/keto reductase; n=1; Petrotoga mob... 38 0.31
UniRef50_A0ZZJ3 Cluster: Oxidoreductase; n=2; Bifidobacterium ad... 38 0.31
UniRef50_A7PNT1 Cluster: Chromosome chr8 scaffold_23, whole geno... 38 0.31
UniRef50_A6RNJ6 Cluster: Putative uncharacterized protein; n=1; ... 38 0.31
UniRef50_Q2JHT1 Cluster: Aldo/keto reductase Tas; n=25; cellular... 38 0.41
UniRef50_Q13GB1 Cluster: Aldo/keto reductase; n=1; Burkholderia ... 38 0.41
UniRef50_Q03I00 Cluster: Aryl-alcohol dehydrogenase related enzy... 38 0.41
UniRef50_A6VXU3 Cluster: Aldo/keto reductase; n=14; Proteobacter... 38 0.41
UniRef50_A0ZMD5 Cluster: Tas; n=1; Nodularia spumigena CCY 9414|... 38 0.41
UniRef50_A0QHX8 Cluster: General stress protein 69; n=2; Mycobac... 38 0.41
UniRef50_Q9HI90 Cluster: NDP-hexose 2, 3-enoyl reductase TylCII ... 38 0.41
UniRef50_UPI0000E87D03 Cluster: Aldo/keto reductase; n=1; Methyl... 38 0.54
UniRef50_Q39MY8 Cluster: Aldo/keto reductase; n=10; Bacteria|Rep... 38 0.54
UniRef50_Q1VSU3 Cluster: Aryl-alcohol dehydrogenase; n=1; Psychr... 38 0.54
UniRef50_Q0B0F0 Cluster: Oxidoreductase; n=1; Syntrophomonas wol... 38 0.54
UniRef50_Q03UP2 Cluster: Aryl-alcohol dehydrogenase family enzym... 38 0.54
UniRef50_Q034L5 Cluster: Aryl-alcohol dehydrogenase related enzy... 38 0.54
UniRef50_A3LSR5 Cluster: D-threo-aldose 1-dehydrogenase; n=5; Sa... 38 0.54
UniRef50_Q2NEM6 Cluster: Putative oxidoreductase; n=1; Methanosp... 38 0.54
UniRef50_UPI0000519C03 Cluster: PREDICTED: similar to CG18547-PA... 37 0.72
UniRef50_Q67NQ1 Cluster: Oxidoreductase; n=1; Symbiobacterium th... 37 0.72
UniRef50_Q39EI1 Cluster: Aldo/keto reductase; n=12; Burkholderia... 37 0.72
UniRef50_Q3I1P2 Cluster: Aldo-keto oxidoreductase; n=6; Bacteria... 37 0.72
UniRef50_Q08NK7 Cluster: Aldo/keto reductase; n=1; Stigmatella a... 37 0.72
UniRef50_A4CIJ8 Cluster: Putative uncharacterized protein; n=2; ... 37 0.72
UniRef50_A3I0G0 Cluster: Oxidoreductase; n=1; Algoriphagus sp. P... 37 0.72
UniRef50_Q016B0 Cluster: COG0667: Predicted oxidoreductases; n=4... 37 0.72
UniRef50_Q54CX8 Cluster: Putative uncharacterized protein; n=1; ... 37 0.72
UniRef50_Q75DD3 Cluster: ABR094Wp; n=1; Eremothecium gossypii|Re... 37 0.72
UniRef50_Q6CI80 Cluster: Similar to tr|O59826 Schizosaccharomyce... 37 0.72
UniRef50_A5UL55 Cluster: Predicted oxidoreductase, aldo/keto red... 37 0.72
UniRef50_A3H9H5 Cluster: Aldo/keto reductase; n=2; Archaea|Rep: ... 37 0.72
UniRef50_Q97L01 Cluster: Fe-S oxidoreductase; n=4; Clostridium|R... 37 0.95
UniRef50_Q2AQ04 Cluster: Aldo/keto reductase; n=7; Bacillus cere... 37 0.95
UniRef50_A6VXX8 Cluster: Aldo/keto reductase; n=2; Marinomonas|R... 37 0.95
UniRef50_A6CMV7 Cluster: Putative uncharacterized protein; n=2; ... 37 0.95
UniRef50_A0UVR1 Cluster: Aldo/keto reductase; n=3; Bacteria|Rep:... 37 0.95
UniRef50_A5UJH5 Cluster: Predicted oxidoreductase, aldo/keto red... 37 0.95
UniRef50_Q81RN9 Cluster: Oxidoreductase, aldo/keto reductase fam... 36 1.3
UniRef50_Q6XUT6 Cluster: Oxido-reductase/dehydratase; n=3; Bacte... 36 1.3
UniRef50_Q1MJ49 Cluster: Putative general stress protein; n=2; R... 36 1.3
UniRef50_Q2NGY0 Cluster: Predicted oxidoreductase; n=1; Methanos... 36 1.3
UniRef50_Q2FL62 Cluster: Aldo/keto reductase; n=1; Methanospiril... 36 1.3
UniRef50_P0A9T5 Cluster: Protein tas; n=88; Bacteria|Rep: Protei... 36 1.3
UniRef50_Q8DHB7 Cluster: Tlr2042 protein; n=16; Cyanobacteria|Re... 36 1.7
UniRef50_Q8A1P5 Cluster: Putative oxidoreductase; n=3; Bacteroid... 36 1.7
UniRef50_Q7NH41 Cluster: Gll2696 protein; n=1; Gloeobacter viola... 36 1.7
UniRef50_Q2NSC7 Cluster: Putative oxidoreductase; n=1; Sodalis g... 36 1.7
UniRef50_Q3WFK9 Cluster: Aldo/keto reductase precursor; n=1; Fra... 36 1.7
UniRef50_A7B5J6 Cluster: Putative uncharacterized protein; n=1; ... 36 1.7
UniRef50_A6WDF5 Cluster: Aldo/keto reductase; n=5; Bacteria|Rep:... 36 1.7
UniRef50_A4E7S8 Cluster: Putative uncharacterized protein; n=1; ... 36 1.7
UniRef50_A1SGJ5 Cluster: Aldo/keto reductase precursor; n=1; Noc... 36 1.7
UniRef50_A1RA11 Cluster: Oxidoreductase, aldo/keto reductase fam... 36 1.7
UniRef50_A6SJ74 Cluster: Putative uncharacterized protein; n=1; ... 36 1.7
>UniRef50_Q9Y020 Cluster: 3-dehydroecdysone 3beta-reductase
precursor; n=1; Spodoptera littoralis|Rep:
3-dehydroecdysone 3beta-reductase precursor - Spodoptera
littoralis (Egyptian cotton leafworm)
Length = 345
Score = 153 bits (372), Expect = 5e-36
Identities = 82/201 (40%), Positives = 116/201 (57%), Gaps = 2/201 (0%)
Frame = +3
Query: 72 AGFLFCLSALCFTSADLIVPTLQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIY 251
A F+ L+ SA + VP L++ + +P +ALGT+LG G V V+
Sbjct: 4 ASFILLLACCGAMSATIDVPMLKMLNDREMPAIALGTYLGFDKGGAVTSKDKQLRNVVMQ 63
Query: 252 ALEAGYTHIDTAYKYGIEDQVGRALTKKFSEG-LKRESIFITTKLWNSYHEREQVIPALR 428
A++ GY H DTA Y E +VG A+ K EG +KRE +F+TTKLWN++H+REQV A++
Sbjct: 64 AIDLGYRHFDTAAIYNTEAEVGEAIRMKIDEGVIKREDVFLTTKLWNTHHKREQVAVAMK 123
Query: 429 KSLENLNLEYVDLYLIHWPIAMFENDTLLDNVDFLDTWRGMIDAKKLGLTKS*ASPTLTR 608
++L L+YVDL+L+HWPIA+ E D N D+L+TWR + KLG TKS +
Sbjct: 124 ETLNKTGLDYVDLFLMHWPIALNE-DYSHSNTDYLETWRATEEMVKLGYTKSIGLSNFNK 182
Query: 609 TNPEDHRQR-TGEXSALQIEL 668
Q T + ALQIE+
Sbjct: 183 LQVATVLQECTIKPVALQIEV 203
>UniRef50_Q8WRT0 Cluster: 3-dehydrecdysone 3b-reductase; n=1;
Trichoplusia ni|Rep: 3-dehydrecdysone 3b-reductase -
Trichoplusia ni (Cabbage looper)
Length = 308
Score = 149 bits (362), Expect = 9e-35
Identities = 81/154 (52%), Positives = 101/154 (65%), Gaps = 2/154 (1%)
Frame = +3
Query: 129 PTLQLSSGGNIPVVALGTW-LGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIE 305
P QL+ G IP +ALGT+ G PK QAV++A++AGY HIDTA YG E
Sbjct: 25 PLKQLNDGNAIPSLALGTFGFGDIPK---------VRQAVLWAIQAGYRHIDTAALYGNE 75
Query: 306 DQVGRALTKKFSEGL-KRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHW 482
++VG+ + +GL KRE +F+TTKLWN H R QV+PALR+SL L L YVDLYLIH
Sbjct: 76 EEVGKGIADAIQQGLVKREELFVTTKLWNDKHGRHQVVPALRESLTKLGLSYVDLYLIHS 135
Query: 483 PIAMFENDTLLDNVDFLDTWRGMIDAKKLGLTKS 584
P A EN +D +D L+TW GM +AKKLGL KS
Sbjct: 136 PEATNENGDPVD-IDVLNTWNGMEEAKKLGLAKS 168
>UniRef50_UPI00015B56A2 Cluster: PREDICTED: similar to GA10458-PA;
n=2; Nasonia vitripennis|Rep: PREDICTED: similar to
GA10458-PA - Nasonia vitripennis
Length = 569
Score = 139 bits (336), Expect = 1e-31
Identities = 69/164 (42%), Positives = 106/164 (64%), Gaps = 11/164 (6%)
Frame = +3
Query: 126 VPTLQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIE 305
VPT+ + G +P++ LGT+L +P G+V + AV YA+E GY H+DTA+ Y E
Sbjct: 3 VPTVTFNDGYKMPMIGLGTFLS-KP-GEVAE-------AVKYAIEVGYRHVDTAFFYENE 53
Query: 306 DQVGRALTKKFSEG-LKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHW 482
++G A+ +K ++G +KRE IF+TTKLW + H+ ++V+PA +KSLENL +Y+DL+L+HW
Sbjct: 54 KEIGSAIREKINDGTIKREDIFVTTKLWCNSHKEDEVVPACKKSLENLGFDYIDLFLVHW 113
Query: 483 PIAMFENDTL----------LDNVDFLDTWRGMIDAKKLGLTKS 584
P A D L + D+L+TW+GM + K+ GL +S
Sbjct: 114 PFAFKSGDALTPRDAAGKIEFSDTDYLETWKGMEECKRQGLARS 157
Score = 109 bits (262), Expect = 1e-22
Identities = 51/114 (44%), Positives = 74/114 (64%), Gaps = 8/114 (7%)
Frame = +3
Query: 267 YTHIDTAYKYGIEDQVGRALTKKFSEG-LKRESIFITTKLWNSYHEREQVIPALRKSLEN 443
Y HIDTAY Y E +G A+ +K +G +KRE +F+TTKL H+ +V+PA ++SL +
Sbjct: 301 YRHIDTAYLYDNEKYIGNAIREKIKDGTVKREDLFVTTKLSYYAHKESEVVPACKQSLND 360
Query: 444 LNLEYVDLYLIHWPIAMF-------ENDTLLDNVDFLDTWRGMIDAKKLGLTKS 584
L L+Y+DLYLIHWPI + LL + D+L+TW+GM + K+ GL +S
Sbjct: 361 LGLDYIDLYLIHWPIRRYFRHNKNASGKLLLSDTDYLETWKGMEECKRQGLARS 414
>UniRef50_UPI00015B56A3 Cluster: PREDICTED: similar to aldo-keto
reductase; n=1; Nasonia vitripennis|Rep: PREDICTED:
similar to aldo-keto reductase - Nasonia vitripennis
Length = 321
Score = 133 bits (322), Expect = 6e-30
Identities = 68/164 (41%), Positives = 101/164 (61%), Gaps = 11/164 (6%)
Frame = +3
Query: 126 VPTLQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIE 305
V + LS G +PV+ LGTW G +V E AV A++AGY H D A YG E
Sbjct: 5 VDEITLSDGNKVPVLGLGTWQGGNDPDEV-------ENAVKLAIDAGYRHFDCASFYGNE 57
Query: 306 DQVGRALTKKFSEGL-KRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHW 482
++G+A+ +K +G+ KRE +F+ TK+WN ++E V+ A ++SL+ L L Y+DLYL+HW
Sbjct: 58 AEIGKAIQEKIDQGVVKREDLFVVTKVWNDERKQELVVAACKRSLKKLGLGYIDLYLVHW 117
Query: 483 PIA---MFE-------NDTLLDNVDFLDTWRGMIDAKKLGLTKS 584
P + +++ N LD VD+++TWRGM + KLGLT+S
Sbjct: 118 PFSYPILYQYIVLPTYNAVTLDEVDYIETWRGMEECIKLGLTRS 161
>UniRef50_A3U9Y0 Cluster: Aldehyde reductase; n=5;
Bacteroidetes|Rep: Aldehyde reductase - Croceibacter
atlanticus HTCC2559
Length = 316
Score = 129 bits (311), Expect = 1e-28
Identities = 77/191 (40%), Positives = 107/191 (56%), Gaps = 12/191 (6%)
Frame = +3
Query: 132 TLQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQ 311
TL+ G +IP + LGTW D ++AV ALE GY HID A Y ED
Sbjct: 3 TLKFRDGDSIPSIGLGTWKSD---------PEDVKKAVKIALENGYKHIDCAAAYDNEDA 53
Query: 312 VGRALTKKFSEG-LKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPI 488
VG A + F G +KRE IF+T+KLWN+ H++E VIPAL+K+L++LNL+Y+DLYL+HWP+
Sbjct: 54 VGEAFKESFESGNVKREDIFVTSKLWNNAHKKEDVIPALKKTLKDLNLDYLDLYLMHWPV 113
Query: 489 AM---------FENDTL-LDNVDFLDTWRGMIDAKKLGLTKS*ASPTLTRTNPEDHRQRT 638
A + D L L+ +T MI+AKK GL K ++ E + +
Sbjct: 114 AFKPSVNGFPEKDEDYLSLEEAPLHETLNAMIEAKKQGLIKHVGVSNFSKEKLESLKGKV 173
Query: 639 GEXSAL-QIEL 668
E + Q+EL
Sbjct: 174 EEMPEMNQVEL 184
>UniRef50_Q8VC28 Cluster: Aldo-keto reductase family 1 member C13;
n=11; Theria|Rep: Aldo-keto reductase family 1 member
C13 - Mus musculus (Mouse)
Length = 323
Score = 124 bits (300), Expect = 3e-27
Identities = 69/161 (42%), Positives = 96/161 (59%), Gaps = 11/161 (6%)
Frame = +3
Query: 135 LQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQV 314
++L+ G IP + GT+ K K V + E A + AL+ GY H+DTAY Y +E+++
Sbjct: 8 VKLNDGHLIPALGFGTY-----KPKEVPKSKSLEAACL-ALDVGYRHVDTAYAYQVEEEI 61
Query: 315 GRALTKKFSEGL-KRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPIA 491
G+A+ K G+ KRE +FITTKLW + E V PAL KSL+ L L+YVDLY++H+P+
Sbjct: 62 GQAIQSKIKAGVVKREDLFITTKLWCTCFRPELVKPALEKSLKKLQLDYVDLYIMHYPVP 121
Query: 492 MFEND----------TLLDNVDFLDTWRGMIDAKKLGLTKS 584
M D +LLD VDF DTW + + K GL KS
Sbjct: 122 MKSGDNDFPVNEQGKSLLDTVDFCDTWERLEECKDAGLVKS 162
>UniRef50_Q7JVH6 Cluster: LD24696p; n=2; Sophophora|Rep: LD24696p -
Drosophila melanogaster (Fruit fly)
Length = 311
Score = 123 bits (297), Expect = 6e-27
Identities = 70/162 (43%), Positives = 99/162 (61%), Gaps = 8/162 (4%)
Frame = +3
Query: 123 IVPTLQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGI 302
+ PT++L++G +P + LGTW +D + +AL+ GY H+DTA+ Y
Sbjct: 4 LAPTIRLNNGREMPTLGLGTWKSFE---------SDAYHSTRHALDVGYRHLDTAFVYEN 54
Query: 303 EDQVGRALTKKFSEGL-KRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIH 479
E +VG+A+++K +EG+ RE +F+TTKL +H+ V A R SL NL LEYVDLYL+H
Sbjct: 55 EAEVGQAISEKIAEGVVTREEVFVTTKLGGIHHDPALVERACRLSLSNLGLEYVDLYLMH 114
Query: 480 WPIAM-FEND-----TL-LDNVDFLDTWRGMIDAKKLGLTKS 584
P+ F ND TL L +VD+LDTWR M LGLT+S
Sbjct: 115 MPVGQKFHNDSNVHGTLELTDVDYLDTWREMEKLVDLGLTRS 156
>UniRef50_Q54B70 Cluster: Aldehyde reductase; n=2; Dictyostelium
discoideum|Rep: Aldehyde reductase - Dictyostelium
discoideum AX4
Length = 297
Score = 122 bits (295), Expect = 1e-26
Identities = 71/162 (43%), Positives = 95/162 (58%), Gaps = 10/162 (6%)
Frame = +3
Query: 129 PTLQLSSGGNIPVVALGTWLGHRPK-GKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIE 305
P+ +LSSG IP+V GTW GK V+V AL+AGY HID A Y E
Sbjct: 3 PSFKLSSGHKIPLVGFGTWKAETTLVGKAVEV----------ALDAGYRHIDCAAVYLNE 52
Query: 306 DQVGRALTKKFSEG--LKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIH 479
+VG A TKKF+ +KRE +FIT+KLWN++H++E V PAL ++L +L L+Y+DLYL+H
Sbjct: 53 KEVGEAFTKKFTTEATVKREDVFITSKLWNTFHKKEHVRPALERTLSDLGLQYLDLYLVH 112
Query: 480 WPIAM--FEND-----TLLDNVDFLDTWRGMIDAKKLGLTKS 584
WP+A ND + + V +TW M GL KS
Sbjct: 113 WPVAFEYTSNDIQTSGSTQEFVSIRETWEEMEKLVDAGLVKS 154
>UniRef50_Q2LZ66 Cluster: GA19341-PA; n=2; Endopterygota|Rep:
GA19341-PA - Drosophila pseudoobscura (Fruit fly)
Length = 315
Score = 122 bits (295), Expect = 1e-26
Identities = 70/164 (42%), Positives = 96/164 (58%), Gaps = 12/164 (7%)
Frame = +3
Query: 129 PTLQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIED 308
P+ LSSG N+P+V LGTW R +VV QAV A++ GY H D A+ YG E
Sbjct: 4 PSFLLSSGRNMPMVGLGTW---RSPPEVVA------QAVKDAIDIGYRHFDCAHIYGNEL 54
Query: 309 QVGRALTKKFSEGL-KRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWP 485
VG A+ +K EGL R+ +FIT+KLWN++H+ E V A SL NL ++Y+DLYL+HWP
Sbjct: 55 HVGVAIREKIQEGLVTRDELFITSKLWNTFHKPELVRAACETSLRNLGIDYLDLYLMHWP 114
Query: 486 IAMFENDTL-----------LDNVDFLDTWRGMIDAKKLGLTKS 584
+A D L +++D+LDTW+ M D GL +
Sbjct: 115 MAYKSGDNLYPTCPDTGKAVFEDIDYLDTWKAMEDLVDSGLVNA 158
>UniRef50_A5E082 Cluster: GCY protein; n=4; Saccharomycetales|Rep:
GCY protein - Lodderomyces elongisporus (Yeast)
(Saccharomyces elongisporus)
Length = 295
Score = 120 bits (288), Expect = 8e-26
Identities = 66/148 (44%), Positives = 88/148 (59%), Gaps = 1/148 (0%)
Frame = +3
Query: 132 TLQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQ 311
T L++G IP + LGTWL +A + AL+ GY HIDTA YG EDQ
Sbjct: 11 TYTLNNGLKIPAIGLGTWLADEEDAAY--------KATLTALKNGYKHIDTAAAYGNEDQ 62
Query: 312 VGRALTKKFSEGLKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPIA 491
VGRA+ G+ R+ IF+TTKLWN H+ + AL +SL+ L LEYVDLYLIHWP++
Sbjct: 63 VGRAIA---DSGVSRDEIFVTTKLWNDQHKDPE--GALDESLKKLGLEYVDLYLIHWPLS 117
Query: 492 MF-ENDTLLDNVDFLDTWRGMIDAKKLG 572
+ + + D+ DF+DTWR + K G
Sbjct: 118 VDPKTEKPYDDYDFVDTWRNLQKIYKEG 145
>UniRef50_Q41399 Cluster: Chalcone reductase; n=4;
eudicotyledons|Rep: Chalcone reductase - Sesbania
rostrata
Length = 322
Score = 118 bits (283), Expect = 3e-25
Identities = 61/167 (36%), Positives = 96/167 (57%), Gaps = 10/167 (5%)
Frame = +3
Query: 114 ADLIVPTLQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYK 293
A+ +P + L+SG +PV+ +GT + RP V+ + A++ GY H D+A
Sbjct: 2 AEKKIPEVLLNSGHKMPVIGMGTSVESRPSNDVLA------SIFVDAIQVGYRHFDSASV 55
Query: 294 YGIEDQVGRALTKKFSEGL--KRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDL 467
YG E+ +G A++K +GL R+ +FIT+K WN+ + ++PAL+ +L+ L +EYVDL
Sbjct: 56 YGTEEAIGMAVSKAIEQGLIKSRDEVFITSKPWNTDAHHDLIVPALKTTLKKLGMEYVDL 115
Query: 468 YLIHWPIAM---FENDTLLDNVDFL-----DTWRGMIDAKKLGLTKS 584
YLIHWP+ + EN + D L TW+ M + +LGL KS
Sbjct: 116 YLIHWPVRLRHDLENPVIFSKEDLLPFDIEGTWKAMEECYRLGLAKS 162
>UniRef50_Q96UH3 Cluster: Aldehyde reductase; n=13;
Pezizomycotina|Rep: Aldehyde reductase - Coccidioides
posadasii
Length = 314
Score = 117 bits (281), Expect = 6e-25
Identities = 65/161 (40%), Positives = 92/161 (57%), Gaps = 10/161 (6%)
Frame = +3
Query: 132 TLQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQ 311
T +L++G +IP + GTW Q N E AV+ AL AGY HIDTA YG E
Sbjct: 7 TFRLNTGEDIPAIGFGTW----------QDENAQEDAVLTALSAGYRHIDTAAVYGTEKA 56
Query: 312 VGRALTKKFSEGLKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPIA 491
+GRAL + L R+ +FIT+KLWN+ H E V A+ +SL+NL ++Y+DLYL+HWP A
Sbjct: 57 IGRALARS---RLSRDELFITSKLWNNKHRPEDVEQAIDQSLKNLEIDYLDLYLMHWPAA 113
Query: 492 MFENDTLLD----------NVDFLDTWRGMIDAKKLGLTKS 584
D + ++D++DT++ M K G TK+
Sbjct: 114 FAPGDDMFPKDSQGNSKTVDIDYVDTYKAMEKLVKSGKTKA 154
>UniRef50_Q7PCV3 Cluster: ENSANGP00000031808; n=9;
Endopterygota|Rep: ENSANGP00000031808 - Anopheles
gambiae str. PEST
Length = 316
Score = 116 bits (280), Expect = 7e-25
Identities = 62/166 (37%), Positives = 92/166 (55%), Gaps = 12/166 (7%)
Frame = +3
Query: 123 IVPTLQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGI 302
+VP +G +IP+ LGTW + P G+V Q D A++ GY HID A+ Y
Sbjct: 5 VVPNAIFKNGNSIPMFGLGTW--NSPPGQVAQAVKD-------AIDVGYRHIDCAHVYQN 55
Query: 303 EDQVGRALTKKFSEGL-KRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIH 479
E +VG + K +EG+ KRE +F+T+KLWN++H + V A + +L+NL L+Y+DLYLIH
Sbjct: 56 EHEVGEGIAAKIAEGVVKREDLFVTSKLWNTFHRPDLVEGACKTTLQNLKLDYLDLYLIH 115
Query: 480 WPIAMFENDT-----------LLDNVDFLDTWRGMIDAKKLGLTKS 584
WP+ E L + D++DTW M GL ++
Sbjct: 116 WPVGYQEGTELFPMGPDGKTFLFSDADYVDTWPEMEKLVDAGLVRN 161
>UniRef50_Q9VTL0 Cluster: CG6083-PA; n=4; Diptera|Rep: CG6083-PA -
Drosophila melanogaster (Fruit fly)
Length = 322
Score = 115 bits (277), Expect = 2e-24
Identities = 65/165 (39%), Positives = 97/165 (58%), Gaps = 13/165 (7%)
Frame = +3
Query: 129 PTLQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIED 308
P LS+G N+P++ LGTW R +VV QAV A++ GY H D A+ YG E
Sbjct: 4 PNFLLSNGKNMPMLGLGTW---RSPPEVVT------QAVKDAIDIGYRHFDCAHIYGNEA 54
Query: 309 QVGRALTKKFSEGL-KRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWP 485
QVG AL +K EG+ R+ +FIT+KLWN++H+ + V PA S+ NL ++Y++LYL+HWP
Sbjct: 55 QVGAALREKMDEGVVTRDELFITSKLWNTHHKPDLVRPACETSIRNLGVKYLNLYLMHWP 114
Query: 486 IAMFE------------NDTLLDNVDFLDTWRGMIDAKKLGLTKS 584
+A N +++D++DTWR M + GL ++
Sbjct: 115 MAYKSGSDNLYPTCPDTNKAAFEDIDYVDTWRAMENLVDEGLCQA 159
>UniRef50_UPI0000588153 Cluster: PREDICTED: hypothetical protein;
n=1; Strongylocentrotus purpuratus|Rep: PREDICTED:
hypothetical protein - Strongylocentrotus purpuratus
Length = 333
Score = 114 bits (275), Expect = 3e-24
Identities = 73/192 (38%), Positives = 101/192 (52%), Gaps = 14/192 (7%)
Frame = +3
Query: 132 TLQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQ 311
++ L SG +P+V LGTW K K +V A+ A++AGY H D A YG E +
Sbjct: 4 SVTLPSGHAMPLVGLGTW-----KLKADEVAG----AIGAAVDAGYRHFDCALIYGNEKE 54
Query: 312 VGRALTKKFSE-GLKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPI 488
VG AL + GLKRE +FITTK+WN++H +E V +SL +L L+Y+DLY++HWP+
Sbjct: 55 VGVALREAMQRLGLKREDVFITTKVWNTFHAKEDVAECFNRSLTDLQLDYIDLYIMHWPL 114
Query: 489 --------AMF----ENDTLLDNVDFLDTWRGMIDAKKLGLTKS*ASPTLTRTNPEDHRQ 632
MF D + +V +L+TW M D K G KS +D Q
Sbjct: 115 GFQNLGPTVMFPRTETGDIVYSDVHYLETWSAMEDLVKTGKCKSLGLSNFNSKQLDDVLQ 174
Query: 633 R-TGEXSALQIE 665
T S LQ+E
Sbjct: 175 HSTVPPSVLQVE 186
>UniRef50_Q5FK98 Cluster: Oxidoreductase; n=8; Lactobacillales|Rep:
Oxidoreductase - Lactobacillus acidophilus
Length = 285
Score = 113 bits (273), Expect = 5e-24
Identities = 63/147 (42%), Positives = 88/147 (59%)
Frame = +3
Query: 132 TLQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQ 311
T L++G IP++ GTW P G+V E++V+ AL GY HIDTA YG ED
Sbjct: 9 TYTLNNGVKIPIIGFGTW--QTPDGEVA------EESVLAALNCGYRHIDTASAYGNEDS 60
Query: 312 VGRALTKKFSEGLKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPIA 491
VGRA+ K G+ R +FITTKLWNS H E+ A+ +SL +L L+Y+D+YLIHWP
Sbjct: 61 VGRAIQKS---GINRHELFITTKLWNSDHGYEKTKKAIDQSLLDLKLDYLDMYLIHWPNP 117
Query: 492 MFENDTLLDNVDFLDTWRGMIDAKKLG 572
D + ++ ++WR M +A + G
Sbjct: 118 SSMRDHWAE-IN-AESWRAMEEAVRAG 142
>UniRef50_Q6TY50 Cluster: Reductase 2; n=10; Magnoliophyta|Rep:
Reductase 2 - Hydrangea macrophylla (Bigleaf hydrangea)
Length = 321
Score = 113 bits (273), Expect = 5e-24
Identities = 67/163 (41%), Positives = 96/163 (58%), Gaps = 10/163 (6%)
Frame = +3
Query: 126 VPTLQLSSGGN-IPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGI 302
+P + LSSGG +PV+ LGT + V+ +AV AL+ GY H DTA Y
Sbjct: 5 IPEVPLSSGGRKMPVLGLGTAADPPVDPETVR------KAVTEALKLGYRHFDTAALYNS 58
Query: 303 EDQVGRALTKKFSEGL--KRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLI 476
E +G A+ + EGL R+ +FIT+KLW S RE V PAL+K+L+NL LEY+D+YLI
Sbjct: 59 EQPLGDAIAEALGEGLIKSRDELFITSKLWCSDAHRENVEPALQKTLKNLKLEYIDMYLI 118
Query: 477 HWPIAM----FENDTLLDN---VDFLDTWRGMIDAKKLGLTKS 584
HWP++ +E ++ +D+ W M + +KLGLTK+
Sbjct: 119 HWPVSSKPGNYEYPIKKEDFLQMDYKSVWEAMEECQKLGLTKA 161
>UniRef50_Q2UGR1 Cluster: Aldo/keto reductase family proteins; n=2;
Ascomycota|Rep: Aldo/keto reductase family proteins -
Aspergillus oryzae
Length = 323
Score = 113 bits (273), Expect = 5e-24
Identities = 69/161 (42%), Positives = 94/161 (58%), Gaps = 15/161 (9%)
Frame = +3
Query: 132 TLQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQ 311
T +L+SG NIP + LGTWL +P ++ E AV AL AGY HID A Y E++
Sbjct: 6 TFKLNSGYNIPAIGLGTWLS-KP--------HEVENAVEAALRAGYRHIDAAACYQNENE 56
Query: 312 VGRALTKKFSEGLKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPIA 491
VG K G+ R+ IFIT+KLWN++H E V A+ K+L++L +Y+DLYLIHWP+A
Sbjct: 57 VGNGWKKS---GVPRDQIFITSKLWNTHHHPEHVEEAVNKTLKDLQTDYLDLYLIHWPVA 113
Query: 492 M-FENDTL-----------LDNVDFLDTWRG---MIDAKKL 569
N+TL L NV DTW +++AKK+
Sbjct: 114 FEHTNETLTPIDPVTKRFRLANVPIADTWAALEKLVEAKKI 154
>UniRef50_Q88SL1 Cluster: Oxidoreductase; n=51; Lactobacillales|Rep:
Oxidoreductase - Lactobacillus plantarum
Length = 286
Score = 113 bits (272), Expect = 7e-24
Identities = 67/153 (43%), Positives = 88/153 (57%), Gaps = 2/153 (1%)
Frame = +3
Query: 108 TSADLIVPTLQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTA 287
T+ + T L++G IP+V GTW P G+V +V+ AL+AGY HIDTA
Sbjct: 2 TALTKLTDTYTLNNGTKIPIVGFGTW--QTPDGQVAY------DSVLAALKAGYRHIDTA 53
Query: 288 YKYGIEDQVGRALTKKFSEGLKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDL 467
YG E+ VG+A+ G+ RE +F+TTKLWN+ H + AL SL L L+YVDL
Sbjct: 54 AAYGNEESVGKAIA---DSGVAREDLFVTTKLWNADHGYDAAKKALDTSLAKLGLDYVDL 110
Query: 468 YLIHW--PIAMFENDTLLDNVDFLDTWRGMIDA 560
YLIHW P AM +N L+ DTWR M +A
Sbjct: 111 YLIHWPNPAAMRDNWEQLN----ADTWRAMEEA 139
>UniRef50_Q8K023 Cluster: Aldo-keto reductase family 1 member C18;
n=72; Tetrapoda|Rep: Aldo-keto reductase family 1 member
C18 - Mus musculus (Mouse)
Length = 323
Score = 112 bits (269), Expect = 2e-23
Identities = 60/164 (36%), Positives = 93/164 (56%), Gaps = 11/164 (6%)
Frame = +3
Query: 126 VPTLQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIE 305
+ ++L+ G +IPV+ GT+ + + ++ A++ G+ HID ++ Y E
Sbjct: 5 IQKIELNDGHSIPVLGFGTYATEE------HLKKKSMESTKIAIDVGFCHIDCSHLYQNE 58
Query: 306 DQVGRALTKKFSEG-LKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHW 482
+++G+A+ K +G +KRE IF T+KLW++ H E V P+L SL LNL+YVDLYLIH+
Sbjct: 59 EEIGQAILSKIEDGTVKREDIFYTSKLWSTSHRPELVRPSLENSLRKLNLDYVDLYLIHF 118
Query: 483 PIAMFENDTLL----------DNVDFLDTWRGMIDAKKLGLTKS 584
P+++ + LL D VD DTW M K GL KS
Sbjct: 119 PVSLKPGNELLPKDEHGNLIFDTVDLCDTWEAMEKCKDAGLAKS 162
>UniRef50_Q0VGY1 Cluster: 3-alpha-hydroxysteroid dehydrogenase;
n=13; Tetrapoda|Rep: 3-alpha-hydroxysteroid
dehydrogenase - Xenopus tropicalis (Western clawed frog)
(Silurana tropicalis)
Length = 324
Score = 110 bits (265), Expect = 5e-23
Identities = 61/162 (37%), Positives = 92/162 (56%), Gaps = 12/162 (7%)
Frame = +3
Query: 135 LQLSSGGNIPVVALGTWLGHR-PKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQ 311
++L+ G +PV+ GT+ + PK E+ A++ GY HID A+ YG E++
Sbjct: 9 VELNDGHKMPVIGFGTYAPPKFPKSLA-------EEGTKVAIDVGYRHIDCAFLYGNEEE 61
Query: 312 VGRALTKKFSEG-LKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPI 488
VGRA+ K ++G +KRE +F T KLW++ H E+V PAL KSL++L L+Y+DL++IH P+
Sbjct: 62 VGRAIRAKIADGTVKREDVFYTGKLWSTSHTPERVRPALEKSLKDLQLDYMDLFIIHMPM 121
Query: 489 AMFENDTLL----------DNVDFLDTWRGMIDAKKLGLTKS 584
D L N D DTW+ + K GL +S
Sbjct: 122 EFKPGDDLFPADENGKFIYHNTDLRDTWKALEKCKDAGLVRS 163
>UniRef50_Q17DN0 Cluster: Aldo-keto reductase; n=5; Culicidae|Rep:
Aldo-keto reductase - Aedes aegypti (Yellowfever
mosquito)
Length = 324
Score = 110 bits (265), Expect = 5e-23
Identities = 67/157 (42%), Positives = 95/157 (60%), Gaps = 15/157 (9%)
Frame = +3
Query: 126 VPTLQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIE 305
+PT++L++G +P + LGT + KG ++ +AV+ A++ G+ HIDTAY Y E
Sbjct: 6 IPTVKLNNGLEMPAIGLGTSMS---KG------DECCKAVMTAIDEGFRHIDTAYNYRNE 56
Query: 306 DQVGRALTKKFSEGL-KRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHW 482
D VGRA+ K EG+ RE +F+TTKLWN++H + V A KSLE+L L+YVDL+LIH
Sbjct: 57 DVVGRAIRAKIEEGVVTREELFVTTKLWNTFHHPDHVPMAFGKSLEHLGLDYVDLFLIHM 116
Query: 483 PIAMF------ENDTLLD---NV-----DFLDTWRGM 551
P E T LD NV D++DTW+ M
Sbjct: 117 PFGYEFNGWDPEKRTPLDDNGNVLCSDDDYVDTWKAM 153
>UniRef50_UPI000023D0F1 Cluster: hypothetical protein FG03517.1;
n=1; Gibberella zeae PH-1|Rep: hypothetical protein
FG03517.1 - Gibberella zeae PH-1
Length = 364
Score = 110 bits (264), Expect = 6e-23
Identities = 61/144 (42%), Positives = 87/144 (60%), Gaps = 1/144 (0%)
Frame = +3
Query: 156 NIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQVGRALTKK 335
+IP LGTWL KG VV AV YAL+ GY HIDTA + ED+VG+ +
Sbjct: 59 DIPAFGLGTWLAG--KGVVVP-------AVEYALKGGYRHIDTALIWRNEDEVGKGIK-- 107
Query: 336 FSEGLKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPIAMF-ENDTL 512
+ G+ R+ I++T KLWN+ H E V A+ S+ NL +EY+DLYLIH+P+A E +
Sbjct: 108 -ASGVSRDEIWVTGKLWNTDHRPELVRKAIETSIANLGVEYLDLYLIHYPVAWVPETRDV 166
Query: 513 LDNVDFLDTWRGMIDAKKLGLTKS 584
+N +DTW+ M + + GLT++
Sbjct: 167 DNNTSLIDTWKAMEELVRAGLTRN 190
>UniRef50_Q1YPE5 Cluster: Aldehyde reductase; n=7; Bacteria|Rep:
Aldehyde reductase - gamma proteobacterium HTCC2207
Length = 330
Score = 110 bits (264), Expect = 6e-23
Identities = 56/124 (45%), Positives = 82/124 (66%), Gaps = 1/124 (0%)
Frame = +3
Query: 126 VPTLQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIE 305
VP +++SS ++P V LG W K+ Q + QAV A++ GY H+D+A YG E
Sbjct: 7 VPGVKVSSK-SMPAVGLGLW-------KITQ--DSAAQAVYEAIKVGYRHLDSAADYGNE 56
Query: 306 DQVGRALTKKFSEGL-KRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHW 482
QVG + + +EGL RE ++ITTKLWN+YH E V A R+S+++L L+Y+DLYL+H+
Sbjct: 57 QQVGEGIARAIAEGLCSREELWITTKLWNTYHRAEHVEAACRRSMDDLGLDYIDLYLVHF 116
Query: 483 PIAM 494
PIA+
Sbjct: 117 PIAL 120
>UniRef50_A2EYY6 Cluster: Oxidoreductase, aldo/keto reductase family
protein; n=9; Trichomonas vaginalis G3|Rep:
Oxidoreductase, aldo/keto reductase family protein -
Trichomonas vaginalis G3
Length = 308
Score = 109 bits (263), Expect = 8e-23
Identities = 66/157 (42%), Positives = 93/157 (59%), Gaps = 16/157 (10%)
Frame = +3
Query: 159 IPVVALGTWLGHRPKGKVVQVTNDTEQAVIYAL-EAGYTHIDTAYKYGIEDQVGRALTKK 335
IP + LGTW R + D A+ YA+ EAGY HID A Y ED VG+AL +
Sbjct: 4 IPTIGLGTWKSPR--------SEDLVNAITYAIKEAGYVHIDCALCYENEDIVGQALQQC 55
Query: 336 FSEGLKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPIAMFEN---- 503
+ G+KRE+I+IT+KLWN++H E V A RK+L++L L+Y+DLYL+H+P A F+N
Sbjct: 56 WDSGIKRENIWITSKLWNTHHRLEIVEEACRKTLKDLRLDYLDLYLMHYPFA-FQNTGIG 114
Query: 504 ----------DTLLDN-VDFLDTWRGMIDAKKLGLTK 581
+T+ D+ V +DTW+ M + GL K
Sbjct: 115 GSLNPLDEKGNTIFDDGVSLIDTWKAMEKLVEKGLVK 151
>UniRef50_P14550 Cluster: Alcohol dehydrogenase [NADP+]; n=44;
Bilateria|Rep: Alcohol dehydrogenase [NADP+] - Homo
sapiens (Human)
Length = 325
Score = 108 bits (260), Expect = 2e-22
Identities = 58/124 (46%), Positives = 76/124 (61%), Gaps = 2/124 (1%)
Frame = +3
Query: 141 LSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQVGR 320
L +G +P++ LGTW K + QV + AV YAL GY HID A YG E ++G
Sbjct: 8 LHTGQKMPLIGLGTW-----KSEPGQV----KAAVKYALSVGYRHIDCAAIYGNEPEIGE 58
Query: 321 ALTKKFSEG--LKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPIAM 494
AL + G + RE +F+T+KLWN+ H E V PALRK+L +L LEY+DLYL+HWP A
Sbjct: 59 ALKEDVGPGKAVPREELFVTSKLWNTKHHPEDVEPALRKTLADLQLEYLDLYLMHWPYAF 118
Query: 495 FEND 506
D
Sbjct: 119 ERGD 122
>UniRef50_A7CUW0 Cluster: 2,5-didehydrogluconate reductase; n=6;
Bacteria|Rep: 2,5-didehydrogluconate reductase -
Opitutaceae bacterium TAV2
Length = 334
Score = 108 bits (259), Expect = 3e-22
Identities = 74/203 (36%), Positives = 103/203 (50%), Gaps = 2/203 (0%)
Frame = +3
Query: 96 ALCFTSADLIVPTLQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYA-LEAGYT 272
A C+T ++PTL LS G +IP + LG W Q+ +D I A AGY
Sbjct: 51 AWCYTMR--MIPTLPLSDGTSIPQLGLGVW----------QMPDDGAGVPIQAAFNAGYR 98
Query: 273 HIDTAYKYGIEDQVGRALTKKFSEGLKRESIFITTKLWNSYHEREQVIPALRKSLENLNL 452
IDTA YG E+ VGRA+ + GL R+ ++ITTK+WNS + + A+R+SL L L
Sbjct: 99 AIDTAPIYGNEEGVGRAIR---ASGLPRKELYITTKVWNSAQGYDSTLRAVRESLGRLQL 155
Query: 453 EYVDLYLIHWPIAMFENDTLLDNVDFLDTWRGMIDAKKLGLTKS*ASPTLTRTNPEDHRQ 632
EYVDLYLIHWP+ + ++DTW+ + K GL +S T +
Sbjct: 156 EYVDLYLIHWPVPKIDR--------YVDTWKALAKIKADGLARSIGVSNFTPVYLQRLFD 207
Query: 633 RTGEXSAL-QIELTSTAHKFHLR 698
TG + Q+EL + LR
Sbjct: 208 ETGIVPVVNQVELHPRLQQHELR 230
>UniRef50_Q8CI22 Cluster: 2310005E10Rik protein; n=30;
Tetrapoda|Rep: 2310005E10Rik protein - Mus musculus
(Mouse)
Length = 316
Score = 107 bits (258), Expect = 3e-22
Identities = 62/159 (38%), Positives = 86/159 (54%), Gaps = 11/159 (6%)
Frame = +3
Query: 141 LSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQVGR 320
L +G +P+V LGTW P KV +AV A++AGY HID AY Y E +VG
Sbjct: 7 LLTGAKMPIVGLGTWKS--PPAKV-------REAVKVAIDAGYRHIDCAYVYQNESEVGE 57
Query: 321 ALTKKFSE-GLKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPIAMF 497
A+ +K E +KRE +FI +KLW+++ E+ V A + +L +L L+Y+DLYLIHWP
Sbjct: 58 AIQEKIQEKAVKREDLFIVSKLWSTFFEKSLVKKAFQNTLSDLKLDYLDLYLIHWPQGFQ 117
Query: 498 ENDTLLDNVD----------FLDTWRGMIDAKKLGLTKS 584
+ L D FLD W M + GL K+
Sbjct: 118 SGNVFLPTDDKGSILSSKYTFLDAWEAMEELVDQGLVKA 156
>UniRef50_A2R6Z3 Cluster: Catalytic activity: an alcohol + NADP(+)
<=> an aldehyde + NADPH; n=9; Pezizomycotina|Rep:
Catalytic activity: an alcohol + NADP(+) <=> an aldehyde
+ NADPH - Aspergillus niger
Length = 345
Score = 107 bits (257), Expect = 4e-22
Identities = 67/176 (38%), Positives = 93/176 (52%), Gaps = 12/176 (6%)
Frame = +3
Query: 132 TLQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQ 311
T +L++G ++P V LGTW + ++ AVI AL+ GY HID A YG E +
Sbjct: 6 TFKLNTGYDMPAVGLGTWQSKK---------DEVRDAVIAALKCGYRHIDAAAVYGNEQE 56
Query: 312 VGRALTKKFSEGLKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPIA 491
VG + G+ RE IF+T+KLWN++H E V A+ KSL +L +Y+DLYLIHWP+A
Sbjct: 57 VGDGMRLS---GVPREEIFLTSKLWNTHHHPENVEEAVDKSLADLQTDYLDLYLIHWPVA 113
Query: 492 ----------MFENDTLLDNVD--FLDTWRGMIDAKKLGLTKS*ASPTLTRTNPED 623
+ E L+D VD DTW M + G +S TR E+
Sbjct: 114 FRYSTTTIQPVNEQTGLIDVVDVPIKDTWAAMEKLVEKGKVRSIGVSNFTREKIEE 169
>UniRef50_Q7QK25 Cluster: ENSANGP00000019775; n=2; Anopheles gambiae
str. PEST|Rep: ENSANGP00000019775 - Anopheles gambiae
str. PEST
Length = 319
Score = 107 bits (256), Expect = 6e-22
Identities = 57/157 (36%), Positives = 97/157 (61%), Gaps = 15/157 (9%)
Frame = +3
Query: 126 VPTLQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIE 305
VPT++ S+G IPV+ GT+L KG+ V++ A++ GY HIDTA+ Y E
Sbjct: 5 VPTVRFSNGYEIPVLGYGTYLAQ--KGQCVELVKK-------AIDLGYRHIDTAFLYENE 55
Query: 306 DQVGRALTKKFSEG-LKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHW 482
++G+A+ K +EG ++RE +F+TTKLWN++H+ + V A R+S + L++ Y+DL+L+H
Sbjct: 56 VEIGQAIRDKIAEGVIRREDVFVTTKLWNTFHDPQHVEEAFRRSFDMLDIGYIDLFLMHS 115
Query: 483 PIAM----FE----------NDTLLDNVDFLDTWRGM 551
P+ + +E + L +VD+++TW+ M
Sbjct: 116 PMGVQFSGYEYADMQPKDAAGNMLFSDVDYVETWKAM 152
>UniRef50_Q23320 Cluster: Putative uncharacterized protein; n=4;
Caenorhabditis|Rep: Putative uncharacterized protein -
Caenorhabditis elegans
Length = 320
Score = 107 bits (256), Expect = 6e-22
Identities = 68/154 (44%), Positives = 87/154 (56%), Gaps = 1/154 (0%)
Frame = +3
Query: 126 VPTLQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIE 305
VP LS+G +P + LGTW +GK V + N A+ AGY HIDTA Y E
Sbjct: 5 VPIFTLSNGVLMPSIGLGTWQMTGEEGKTV-IRN--------AVLAGYRHIDTATLYQNE 55
Query: 306 DQVGRALTKKFSEG-LKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHW 482
Q+G AL + F+EG LKRE IFITTK + + V ALR SL+ L L+YVDLYL H
Sbjct: 56 HQIGDALAELFAEGILKREDIFITTKAFCHEVAPDVVEEALRNSLKRLRLDYVDLYLAHI 115
Query: 483 PIAMFENDTLLDNVDFLDTWRGMIDAKKLGLTKS 584
P + ++ + +V D WRG LGLTK+
Sbjct: 116 PASTKDDGSFRSDVKVEDIWRGFEKVYGLGLTKA 149
>UniRef50_P26690 Cluster: NAD(P)H-dependent 6'-deoxychalcone
synthase; n=3; Papilionoideae|Rep: NAD(P)H-dependent
6'-deoxychalcone synthase - Glycine max (Soybean)
Length = 315
Score = 107 bits (256), Expect = 6e-22
Identities = 57/128 (44%), Positives = 79/128 (61%), Gaps = 9/128 (7%)
Frame = +3
Query: 228 DTEQAVIYALEAGYTHIDTAYKYGIEDQVGRALTKKFSEGL-KRESIFITTKLWNSYHER 404
DT++A+I A++ GY H DTA YG E +G AL + GL R+ +F+T+KLW + +
Sbjct: 37 DTKEAIIEAVKQGYRHFDTAAAYGSEQALGEALKEAIHLGLVSRQDLFVTSKLWVTENHP 96
Query: 405 EQVIPALRKSLENLNLEYVDLYLIHWPIAM--------FENDTLLDNVDFLDTWRGMIDA 560
V+PALRKSL+ L LEY+DLYLIHWP++ E + LL D W M +
Sbjct: 97 HLVLPALRKSLKTLQLEYLDLYLIHWPLSSQPGKFSFPIEVEDLLP-FDVKGVWESMEEC 155
Query: 561 KKLGLTKS 584
+KLGLTK+
Sbjct: 156 QKLGLTKA 163
>UniRef50_UPI000065D0BD Cluster: Homolog of Homo sapiens "AKR1B1
protein.; n=1; Takifugu rubripes|Rep: Homolog of Homo
sapiens "AKR1B1 protein. - Takifugu rubripes
Length = 330
Score = 101 bits (241), Expect(2) = 7e-22
Identities = 54/123 (43%), Positives = 78/123 (63%), Gaps = 1/123 (0%)
Frame = +3
Query: 123 IVPTLQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGI 302
++P++ L++G +PV+ LGTW GK V T +AV A+ AGY HIDTAY Y
Sbjct: 1 MIPSVTLNTGALMPVLGLGTW----KSGKGV-----TTEAVKVAIGAGYRHIDTAYVYEN 51
Query: 303 EDQVGRALTKKFSEGL-KRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIH 479
E +VG + +G+ KRE +FI +KLW ++H V A K+L +LNL+YVDLYL+H
Sbjct: 52 ETEVGAGVQAMIDQGVVKREELFIVSKLWCTFHTPSLVRGACEKTLSSLNLDYVDLYLMH 111
Query: 480 WPI 488
+P+
Sbjct: 112 FPM 114
Score = 26.6 bits (56), Expect(2) = 7e-22
Identities = 11/28 (39%), Positives = 14/28 (50%)
Frame = +3
Query: 501 NDTLLDNVDFLDTWRGMIDAKKLGLTKS 584
N + D FLDTW M + GL K+
Sbjct: 153 NQLICDGTSFLDTWEAMEELVDDGLAKA 180
>UniRef50_Q8SSK6 Cluster: ALDOSE REDUCTASE; n=1; Encephalitozoon
cuniculi|Rep: ALDOSE REDUCTASE - Encephalitozoon
cuniculi
Length = 301
Score = 106 bits (254), Expect = 1e-21
Identities = 69/178 (38%), Positives = 95/178 (53%), Gaps = 11/178 (6%)
Frame = +3
Query: 120 LIVPTLQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYG 299
+I T +L++G IP V LGTW G + + E A+ AL GY HIDTA+ YG
Sbjct: 1 MICKTQKLNNGKEIPTVGLGTW-GMEDEAVL-------EGAIRNALSLGYRHIDTAFIYG 52
Query: 300 IEDQVGRALTKKFSEG-LKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLI 476
E +G L K F EG ++R+ +FIT+KLWN++H + LR+SL +L ++YVDLYLI
Sbjct: 53 NEKMIGNILKKLFDEGVVQRKDLFITSKLWNTFHGCPE--DGLRRSLNDLQMDYVDLYLI 110
Query: 477 HWPIAM-------FENDTLLDNV---DFLDTWRGMIDAKKLGLTKS*ASPTLTRTNPE 620
HWP+ E+ NV D + W+ M LGL KS + N E
Sbjct: 111 HWPVTFDPAPDGTVESCGKKYNVGKFDAVGVWKKMEALVDLGLAKSIGISNFGKANTE 168
>UniRef50_P06632 Cluster: 2,5-diketo-D-gluconic acid reductase A;
n=8; Actinomycetales|Rep: 2,5-diketo-D-gluconic acid
reductase A - Corynebacterium sp. (strain ATCC 31090)
Length = 278
Score = 106 bits (254), Expect = 1e-21
Identities = 61/155 (39%), Positives = 89/155 (57%)
Frame = +3
Query: 120 LIVPTLQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYG 299
+ VP++ L+ G +IP + G + KV DT++AV ALE GY HIDTA YG
Sbjct: 1 MTVPSIVLNDGNSIPQLGYGVF-------KVPPA--DTQRAVEEALEVGYRHIDTAAIYG 51
Query: 300 IEDQVGRALTKKFSEGLKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIH 479
E+ VG A+ + G+ R+ +FITTKLWN H+ ++ A+ +SL L L+ VDLYL+H
Sbjct: 52 NEEGVGAAIA---ASGIARDDLFITTKLWNDRHDGDEPAAAIAESLAKLALDQVDLYLVH 108
Query: 480 WPIAMFENDTLLDNVDFLDTWRGMIDAKKLGLTKS 584
WP +N ++ W MI+ + GLT+S
Sbjct: 109 WPTPAADN--------YVHAWEKMIELRAAGLTRS 135
>UniRef50_Q5BKE9 Cluster: LOC594893 protein; n=5; Xenopus
tropicalis|Rep: LOC594893 protein - Xenopus tropicalis
(Western clawed frog) (Silurana tropicalis)
Length = 345
Score = 105 bits (253), Expect = 1e-21
Identities = 68/177 (38%), Positives = 96/177 (54%), Gaps = 26/177 (14%)
Frame = +3
Query: 132 TLQLSSGGNIPVVALGTWL------------GH---RPKGKVVQVTNDTEQAVIYALEAG 266
++QL G +PVVA GT+ GH G +D A AL+ G
Sbjct: 8 SIQLHDGRWMPVVAFGTFYPFTFPGDSQANPGHCAGTKHGTEKSFIDDVRVATKMALDLG 67
Query: 267 YTHIDTAYKYGIEDQVGRALTKKFSEG-LKRESIFITTKLWNSYHEREQVIPALRKSLEN 443
Y H+D A+ Y E VG+A +KF++G LKRE +F T+KLWN++H+ V PAL K+L
Sbjct: 68 YRHVDGAFLYSSETGVGQAFREKFADGTLKREDLFYTSKLWNTFHQPHLVRPALEKTLSF 127
Query: 444 LNLEYVDLYLIHWPIA------MF---ENDT-LLDNVDFLDTWRGMIDAKKLGLTKS 584
L ++YVDLYLIH P++ +F E+ T D D L TW+ + + + GL KS
Sbjct: 128 LQMDYVDLYLIHMPMSFKPAEELFPKNEDGTCAFDQPDLLQTWQALEECRDAGLVKS 184
>UniRef50_Q2S340 Cluster: Aldehyde reductase; n=10; Bacteria|Rep:
Aldehyde reductase - Salinibacter ruber (strain DSM
13855)
Length = 321
Score = 105 bits (252), Expect = 2e-21
Identities = 62/160 (38%), Positives = 92/160 (57%), Gaps = 10/160 (6%)
Frame = +3
Query: 132 TLQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQ 311
++ +G +P++ LGTW P G+V + AV ALEAGY H+D A Y E +
Sbjct: 3 SISFENGDEMPMIGLGTWKS--PPGEVYE-------AVTTALEAGYRHVDCAPIYKNETE 53
Query: 312 VGRALTKKFSEG-LKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPI 488
VG AL+ F G ++R+ +++T+KLWN+ H + V PAL ++L +L L+ +DLYLIHWP+
Sbjct: 54 VGAALSDSFDAGGIRRDDVWVTSKLWNNAHHPDDVRPALEQTLSDLRLDALDLYLIHWPV 113
Query: 489 AMF-ENDTLLDNVDFL--------DTWRGMIDAKKLGLTK 581
A+ E D DF+ +TW M KK GL +
Sbjct: 114 ALQPEVDFPESPDDFVSPEAVPLTETWAAMEALKKDGLVR 153
>UniRef50_Q01J82 Cluster: OSIGBa0152K17.5 protein; n=28;
Magnoliophyta|Rep: OSIGBa0152K17.5 protein - Oryza
sativa (Rice)
Length = 323
Score = 105 bits (252), Expect = 2e-21
Identities = 64/162 (39%), Positives = 87/162 (53%), Gaps = 9/162 (5%)
Frame = +3
Query: 126 VPTLQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIE 305
VP + L G P+ A+G +G T A + ALE G+ H DTA YG E
Sbjct: 4 VPEVALRHGAGRPMPAVG--VGTADSAATSPETK--RGAALAALEVGFRHFDTAALYGTE 59
Query: 306 DQVGRALTKKFSEGL--KRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIH 479
+G A+ + GL RE +F+TTKLW + V+P+LR+SL NL +EYVDLYL+H
Sbjct: 60 APLGEAIAEATRRGLVASREEVFVTTKLWCTQCHPGLVLPSLRESLRNLQMEYVDLYLVH 119
Query: 480 WPIAMFENDTLL-----DNV--DFLDTWRGMIDAKKLGLTKS 584
WPI++ +L D V DF WR M + +LGL K+
Sbjct: 120 WPISVKPGPPMLPVKREDAVPFDFEGVWRAMEECHRLGLAKA 161
>UniRef50_A6RKL9 Cluster: Putative uncharacterized protein; n=3;
Sclerotiniaceae|Rep: Putative uncharacterized protein -
Botryotinia fuckeliana B05.10
Length = 360
Score = 105 bits (252), Expect = 2e-21
Identities = 60/137 (43%), Positives = 78/137 (56%), Gaps = 2/137 (1%)
Frame = +3
Query: 162 PVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQVGRALTKKFS 341
P++ GTW V N TE AV YA+E GY ID A YG E VGR + +
Sbjct: 40 PLIGFGTW------NLKVSPENTTE-AVAYAIEIGYRQIDCAAVYGNEVAVGRGIEEGLK 92
Query: 342 E-GLKRESIFITTKLWNSYH-EREQVIPALRKSLENLNLEYVDLYLIHWPIAMFENDTLL 515
GLKRE I++T+KLWN +H E V L ++L++L LEY+DLYLIHWPI N
Sbjct: 93 RAGLKREDIWVTSKLWNDHHGSYENVEKGLNQTLQDLGLEYLDLYLIHWPIGFSSNGA-- 150
Query: 516 DNVDFLDTWRGMIDAKK 566
N+D + T++ MI K
Sbjct: 151 KNLDHVQTYKSMISLPK 167
>UniRef50_P15121 Cluster: Aldose reductase; n=72; Eumetazoa|Rep:
Aldose reductase - Homo sapiens (Human)
Length = 316
Score = 105 bits (252), Expect = 2e-21
Identities = 63/161 (39%), Positives = 92/161 (57%), Gaps = 11/161 (6%)
Frame = +3
Query: 135 LQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQV 314
L L++G +P++ LGTW P G+V + AV A++ GY HID A+ Y E++V
Sbjct: 5 LLLNNGAKMPILGLGTWKS--PPGQVTE-------AVKVAIDVGYRHIDCAHVYQNENEV 55
Query: 315 GRALTKKFSEGL-KRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPIA 491
G A+ +K E + KRE +FI +KLW +YHE+ V A +K+L +L L+Y+DLYLIHWP
Sbjct: 56 GVAIQEKLREQVVKREELFIVSKLWCTYHEKGLVKGACQKTLSDLKLDYLDLYLIHWPTG 115
Query: 492 ------MFEND----TLLDNVDFLDTWRGMIDAKKLGLTKS 584
F D + + + LDTW M + GL K+
Sbjct: 116 FKPGKEFFPLDESGNVVPSDTNILDTWAAMEELVDEGLVKA 156
>UniRef50_P14065 Cluster: Protein GCY; n=13; Saccharomycetales|Rep:
Protein GCY - Saccharomyces cerevisiae (Baker's yeast)
Length = 312
Score = 105 bits (251), Expect = 2e-21
Identities = 70/181 (38%), Positives = 95/181 (52%), Gaps = 18/181 (9%)
Frame = +3
Query: 135 LQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQV 314
L L++G IP + LGTW ND +AV+ AL+ GY HIDTA Y EDQV
Sbjct: 12 LSLNTGAQIPQIGLGTWQSKE---------NDAYKAVLTALKDGYRHIDTAAIYRNEDQV 62
Query: 315 GRALTKKFSEGLKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPI-- 488
G+A+ G+ RE IF+TTKLW + H +V AL +SL+ L L+YVDLYL+HWP
Sbjct: 63 GQAIK---DSGVPREEIFVTTKLWCTQHHEPEV--ALDQSLKRLGLDYVDLYLMHWPARL 117
Query: 489 --AMFENDTLLD--------------NVDFLDTWRGMIDAKKLGLTKS*ASPTLTRTNPE 620
A +N+ +L N +F+ TW M + K G TK+ + N +
Sbjct: 118 DPAYIKNEDILSVPTKKDGSRAVDITNWNFIKTWELMQELPKTGKTKAVGVSNFSINNLK 177
Query: 621 D 623
D
Sbjct: 178 D 178
>UniRef50_A7BA05 Cluster: Putative uncharacterized protein; n=1;
Actinomyces odontolyticus ATCC 17982|Rep: Putative
uncharacterized protein - Actinomyces odontolyticus ATCC
17982
Length = 292
Score = 104 bits (250), Expect = 3e-21
Identities = 59/131 (45%), Positives = 79/131 (60%), Gaps = 1/131 (0%)
Frame = +3
Query: 126 VPTLQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIE 305
+PT L +G IPV+ GT+ KV DT AV ALE GY HIDTA YG E
Sbjct: 16 IPTFMLPTGSPIPVLGFGTY-------KVAP--EDTYDAVSRALEVGYRHIDTAQMYGNE 66
Query: 306 DQVGRALTKKFSEGLKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWP 485
+VG AL + G+ RE +FITTK+ NS HE ++ ++R+SLE+L +YVDL L+HWP
Sbjct: 67 AEVGAALE---ASGIAREDLFITTKVDNSNHEPDRAAASIRRSLEDLRTDYVDLLLVHWP 123
Query: 486 I-AMFENDTLL 515
+ ++ D L
Sbjct: 124 LPTLYGGDVAL 134
>UniRef50_A7SIT3 Cluster: Predicted protein; n=1; Nematostella
vectensis|Rep: Predicted protein - Nematostella
vectensis
Length = 323
Score = 104 bits (250), Expect = 3e-21
Identities = 54/119 (45%), Positives = 79/119 (66%), Gaps = 1/119 (0%)
Frame = +3
Query: 138 QLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQVG 317
+L++G +IP +ALGTW + +V N AV A+E GY HID A YG E ++G
Sbjct: 9 KLNTGASIPAMALGTWQSSKE-----EVGN----AVRLAIELGYRHIDCAEIYGNEGEIG 59
Query: 318 RALTKKFSEG-LKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPIA 491
AL++ +EG +KRE +F+T+KLW H + V+PA + +L+NL L+Y+DLYLIH P+A
Sbjct: 60 EALSEVLTEGKVKREELFVTSKLWCDSHHPDDVLPACQATLKNLQLDYLDLYLIHIPVA 118
>UniRef50_P45376 Cluster: Aldose reductase; n=21; Bilateria|Rep:
Aldose reductase - Mus musculus (Mouse)
Length = 316
Score = 104 bits (250), Expect = 3e-21
Identities = 60/161 (37%), Positives = 89/161 (55%), Gaps = 11/161 (6%)
Frame = +3
Query: 135 LQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQV 314
L+L++G +P + LGTW P G+V + AV A++ GY HID A Y E +V
Sbjct: 5 LELNNGTKMPTLGLGTWKS--PPGQVTE-------AVKVAIDLGYRHIDCAQVYQNEKEV 55
Query: 315 GRALTKKFSEGL-KRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPIA 491
G AL +K E + KR+ +FI +KLW ++H++ V A +K+L +L L+Y+DLYLIHWP
Sbjct: 56 GVALQEKLKEQVVKRQDLFIVSKLWCTFHDKSMVKGAFQKTLSDLQLDYLDLYLIHWPTG 115
Query: 492 M----------FENDTLLDNVDFLDTWRGMIDAKKLGLTKS 584
+ + + DF+DTW M GL K+
Sbjct: 116 FKPGPDYFPLDASGNVIPSDTDFVDTWTAMEQLVDEGLVKT 156
>UniRef50_Q6CFG7 Cluster: Yarrowia lipolytica chromosome B of strain
CLIB122 of Yarrowia lipolytica; n=9; Ascomycota|Rep:
Yarrowia lipolytica chromosome B of strain CLIB122 of
Yarrowia lipolytica - Yarrowia lipolytica (Candida
lipolytica)
Length = 337
Score = 103 bits (248), Expect = 6e-21
Identities = 54/121 (44%), Positives = 72/121 (59%)
Frame = +3
Query: 141 LSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQVGR 320
L++G IP + LGTW K +V E A+ E GY HIDTA+ Y ED VG
Sbjct: 36 LNNGKTIPAIGLGTW-----KSTTEEVAGAVECALT---EGGYRHIDTAFNYRNEDAVGL 87
Query: 321 ALTKKFSEGLKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPIAMFE 500
+ + +G+KRE IF+TTK+W +YH+R V L SLE L L+YVD+ LIHWP+ +
Sbjct: 88 GIKRAMEKGVKREDIFVTTKIWVTYHDR--VEENLDMSLERLGLDYVDMLLIHWPVPLNP 145
Query: 501 N 503
N
Sbjct: 146 N 146
>UniRef50_P27800 Cluster: Aldehyde reductase 1; n=18; root|Rep:
Aldehyde reductase 1 - Sporobolomyces salmonicolor
Length = 323
Score = 103 bits (248), Expect = 6e-21
Identities = 63/169 (37%), Positives = 91/169 (53%), Gaps = 15/169 (8%)
Frame = +3
Query: 123 IVPTLQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGI 302
+V T L++G ++ +V GTW + Q V A+E GY H+D A Y
Sbjct: 1 MVGTTTLNTGASLELVGYGTWQA---------APGEVGQGVKVAIETGYRHLDLAKVYSN 51
Query: 303 EDQVGRALTKKFSEGLKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHW 482
+ +VG A+ + G+KRE +FIT+KLWN+ H EQV PAL +L+ L LEY+DLYLIHW
Sbjct: 52 QPEVGAAIKEA---GVKREDLFITSKLWNNSHRPEQVEPALDDTLKELGLEYLDLYLIHW 108
Query: 483 PIA----------MF----ENDTLLD-NVDFLDTWRGMIDAKKLGLTKS 584
P+A +F + + LD V +DTW+ M+ G K+
Sbjct: 109 PVAFPPEGDITQNLFPKANDKEVKLDLEVSLVDTWKAMVKLLDTGKVKA 157
>UniRef50_UPI00015B40FA Cluster: PREDICTED: similar to CG2767-PA;
n=2; Nasonia vitripennis|Rep: PREDICTED: similar to
CG2767-PA - Nasonia vitripennis
Length = 356
Score = 103 bits (247), Expect = 7e-21
Identities = 75/195 (38%), Positives = 102/195 (52%), Gaps = 16/195 (8%)
Frame = +3
Query: 132 TLQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQ 311
T++LSSG ++P++ LGTW P + E AV ALE+GY HIDTA+ YG E+
Sbjct: 27 TIKLSSGHDMPMIGLGTW--QMPPEAI-------EVAVTAALESGYRHIDTAFTYGNEEA 77
Query: 312 VGRALTKKFSEGLKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPIA 491
+G+ L K F +G KRE +FITTKL E V L+ SLE L LEYV++YLIH P A
Sbjct: 78 IGKTLKKWFDKGGKREDLFITTKLPPIGMRAEYVESYLKLSLEKLGLEYVNMYLIHKPFA 137
Query: 492 MF------------ENDTLLD-NVDFLDTWRGMIDAKKLGLTKS*ASPTLTRT---NPED 623
+ +LD + D + WR M K G +S ++ N +
Sbjct: 138 FVKDKYKYEPALNPDGSVVLDTDTDHVAIWRAMEKQVKAGRVRSIGLSNFNKSQLLNVYE 197
Query: 624 HRQRTGEXSALQIEL 668
H + + S LQIEL
Sbjct: 198 HAEI--KPSNLQIEL 210
>UniRef50_Q55FL3 Cluster: Aldo-keto reductase; n=2; Dictyostelium
discoideum AX4|Rep: Aldo-keto reductase - Dictyostelium
discoideum AX4
Length = 321
Score = 103 bits (247), Expect = 7e-21
Identities = 58/127 (45%), Positives = 76/127 (59%), Gaps = 1/127 (0%)
Frame = +3
Query: 138 QLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQVG 317
+L+ G IP + LGT+ P G+V N+ AL+ GY HID A YG E +G
Sbjct: 18 KLNDGNQIPSIGLGTYYSENP-GEVGDAINN-------ALKNGYRHIDGAAFYGNEKVIG 69
Query: 318 RALTKKFSEG-LKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPIAM 494
+L + F EG +KRE IF T+KLWNS H V+ K++E+L + Y+DLYLIHWPIA
Sbjct: 70 NSLKEIFKEGEIKREDIFYTSKLWNSCHNSNLVVKHCVKTIEDLGIGYLDLYLIHWPIA- 128
Query: 495 FENDTLL 515
FEN L
Sbjct: 129 FENSNPL 135
>UniRef50_Q9NAI5 Cluster: Putative uncharacterized protein; n=3;
Caenorhabditis|Rep: Putative uncharacterized protein -
Caenorhabditis elegans
Length = 316
Score = 102 bits (245), Expect = 1e-20
Identities = 63/165 (38%), Positives = 92/165 (55%), Gaps = 11/165 (6%)
Frame = +3
Query: 123 IVPTLQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGI 302
+V +L+L+SG +IP + LGTW +P G+V A+ A+ AGY HID A+ Y
Sbjct: 1 MVQSLKLNSGYSIPAIGLGTWQS-KP-GEVAA-------AIKTAVAAGYRHIDCAHVYQN 51
Query: 303 EDQVGRALTKKFSEG-LKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIH 479
+ +VG AL + EG +KRE +FIT+K+WN++H + + L +L L YVDL LIH
Sbjct: 52 QKEVGEALKEILDEGKVKREELFITSKVWNTFHSEAKAHENIDIILSDLQLSYVDLMLIH 111
Query: 480 WPIAMFENDTLL----------DNVDFLDTWRGMIDAKKLGLTKS 584
WP E L +VD+L+TW+ A+K G +S
Sbjct: 112 WPQGYAEGAELFPAGENGKMRYSDVDYLETWKAFEAAQKAGKCRS 156
>UniRef50_Q968S3 Cluster: Aldoketoreductase-like protein; n=1;
Orconectes limosus|Rep: Aldoketoreductase-like protein -
Orconectes limosus (Spinycheek crayfish)
Length = 336
Score = 101 bits (243), Expect = 2e-20
Identities = 59/129 (45%), Positives = 78/129 (60%), Gaps = 2/129 (1%)
Frame = +3
Query: 126 VPTLQLSSGGNIPVVALGTW-LGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGI 302
+PT+ L+SG +IPV+ LGT LG K VT E A LE GY H D+A YG
Sbjct: 11 IPTILLNSGSHIPVMGLGTGSLGRNGKMSEEAVTAVLETA----LECGYRHFDSAAYYGN 66
Query: 303 EDQVGRALTKKFSEG-LKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIH 479
E +G+ L + SEG +KRE +FITTKL + + V L+KSL+NL L YVDLYL+H
Sbjct: 67 EAIIGQVLRRWISEGKVKREELFITTKLPTRGNREKDVARFLQKSLDNLRLPYVDLYLVH 126
Query: 480 WPIAMFEND 506
+P + + D
Sbjct: 127 YPCGILDTD 135
>UniRef50_A2QBD7 Cluster: Catalytic activity: an alcohol + NADP(+)
<=> an aldehyde + NADPH; n=4; Trichocomaceae|Rep:
Catalytic activity: an alcohol + NADP(+) <=> an aldehyde
+ NADPH - Aspergillus niger
Length = 323
Score = 101 bits (243), Expect = 2e-20
Identities = 61/147 (41%), Positives = 83/147 (56%), Gaps = 10/147 (6%)
Frame = +3
Query: 141 LSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQVGR 320
+++G IP V GTW + K ++V N AV AL GY HID A Y E +VG
Sbjct: 9 INTGAKIPAVGFGTW-----QAKPLEVEN----AVEVALREGYRHIDCAAIYRNETEVGN 59
Query: 321 ALTKKFSEGLKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPIAM-- 494
+ K G+ RE IFIT KLWN+ H E V PAL K+L++L + Y+DLYL+HWP A
Sbjct: 60 GIRKS---GVPREEIFITGKLWNTKHAPEDVEPALDKTLQDLGVAYLDLYLMHWPCAFKG 116
Query: 495 ------FENDTLLD--NVDFLDTWRGM 551
+D + D N+D++ T+R M
Sbjct: 117 GDKWFPLNDDGVFDLANIDYITTYRAM 143
>UniRef50_P28475 Cluster: NADP-dependent D-sorbitol-6-phosphate
dehydrogenase; n=71; Magnoliophyta|Rep: NADP-dependent
D-sorbitol-6-phosphate dehydrogenase - Malus domestica
(Apple) (Malus sylvestris)
Length = 310
Score = 101 bits (242), Expect = 3e-20
Identities = 61/166 (36%), Positives = 89/166 (53%), Gaps = 15/166 (9%)
Frame = +3
Query: 132 TLQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQ 311
T+ LSSG +PV+ LG W + ++ ++ ++ A++ GY H D A Y E
Sbjct: 3 TVTLSSGYEMPVIGLGLWRLEK---------DELKEVILNAIKIGYRHFDCAAHYKSEAD 53
Query: 312 VGRALTKKFSEGL-KRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPI 488
VG AL + F GL KRE +FITTK+WNS H V+ A + SLE L ++Y+DLYL+H+P+
Sbjct: 54 VGEALAEAFKTGLVKREELFITTKIWNSDHGH--VVEACKNSLEKLQIDYLDLYLVHYPM 111
Query: 489 -----------AMFENDTLLD---NVDFLDTWRGMIDAKKLGLTKS 584
++ D +LD + TW GM LGL +S
Sbjct: 112 PTKHNAIGKTASLLGEDKVLDIDVTISLQQTWEGMEKTVSLGLVRS 157
>UniRef50_Q96JD6 Cluster: Aldo-keto reductase family 1 member C-like
protein 2; n=37; Euteleostomi|Rep: Aldo-keto reductase
family 1 member C-like protein 2 - Homo sapiens (Human)
Length = 320
Score = 94.7 bits (225), Expect(2) = 3e-20
Identities = 52/113 (46%), Positives = 68/113 (60%), Gaps = 1/113 (0%)
Frame = +3
Query: 153 GNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQVGRALTK 332
G+IP V L +W GKV + AV A++AGY H D AY Y E +VG +
Sbjct: 2 GDIPAVGLSSWKAS--PGKVTE-------AVKEAIDAGYRHFDCAYFYHNEREVGAGIRC 52
Query: 333 KFSEG-LKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPI 488
K EG ++RE +FI TKLW + H++ V A RKSL+ L L Y+DLYLIHWP+
Sbjct: 53 KIKEGAVRREDLFIATKLWCTCHKKSLVETACRKSLKALKLNYLDLYLIHWPM 105
Score = 27.5 bits (58), Expect(2) = 3e-20
Identities = 12/28 (42%), Positives = 15/28 (53%)
Frame = +3
Query: 501 NDTLLDNVDFLDTWRGMIDAKKLGLTKS 584
N + + DFLDTW M D GL K+
Sbjct: 139 NMVIPSDTDFLDTWEAMEDLVITGLVKN 166
>UniRef50_Q96JD6-2 Cluster: Isoform 2 of Q96JD6 ; n=4;
Catarrhini|Rep: Isoform 2 of Q96JD6 - Homo sapiens
(Human)
Length = 263
Score = 94.7 bits (225), Expect(2) = 3e-20
Identities = 52/113 (46%), Positives = 68/113 (60%), Gaps = 1/113 (0%)
Frame = +3
Query: 153 GNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQVGRALTK 332
G+IP V L +W GKV + AV A++AGY H D AY Y E +VG +
Sbjct: 2 GDIPAVGLSSWKAS--PGKVTE-------AVKEAIDAGYRHFDCAYFYHNEREVGAGIRC 52
Query: 333 KFSEG-LKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPI 488
K EG ++RE +FI TKLW + H++ V A RKSL+ L L Y+DLYLIHWP+
Sbjct: 53 KIKEGAVRREDLFIATKLWCTCHKKSLVETACRKSLKALKLNYLDLYLIHWPM 105
Score = 27.5 bits (58), Expect(2) = 3e-20
Identities = 12/28 (42%), Positives = 15/28 (53%)
Frame = +3
Query: 501 NDTLLDNVDFLDTWRGMIDAKKLGLTKS 584
N + + DFLDTW M D GL K+
Sbjct: 139 NMVIPSDTDFLDTWEAMEDLVITGLVKN 166
>UniRef50_UPI00015B4B22 Cluster: PREDICTED: similar to GA15457-PA;
n=1; Nasonia vitripennis|Rep: PREDICTED: similar to
GA15457-PA - Nasonia vitripennis
Length = 388
Score = 101 bits (241), Expect = 4e-20
Identities = 65/164 (39%), Positives = 91/164 (55%), Gaps = 11/164 (6%)
Frame = +3
Query: 126 VPTLQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIE 305
V L+LSSG IP V LGT +++ ++ + A+ ALE GY HIDTA+ Y E
Sbjct: 23 VEKLKLSSGHEIPAVGLGT--------STIKL-DEMDNAISSALENGYRHIDTAFSYDNE 73
Query: 306 DQVGRALTKKFSEGLKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWP 485
+G+ L K F +G KRE IFIT+KL + + + V L++SL++L L+YVD+YLIH P
Sbjct: 74 AAIGKILKKWFDKGGKREDIFITSKLPSQGNRPQSVETYLKRSLKDLGLDYVDMYLIHTP 133
Query: 486 IAMFENDT-----------LLDNVDFLDTWRGMIDAKKLGLTKS 584
A+ E + L D+VD W+ M K G KS
Sbjct: 134 FAVKEGENLSSKQDKDGNDLFDDVDHKALWKAMERQVKEGRAKS 177
>UniRef50_Q7WSY4 Cluster: Putative aldo-keto reductase; n=1;
Propionibacterium freudenreichii subsp. shermanii|Rep:
Putative aldo-keto reductase - Propionibacterium
freudenreichii subsp. shermanii
Length = 280
Score = 101 bits (241), Expect = 4e-20
Identities = 59/152 (38%), Positives = 87/152 (57%)
Frame = +3
Query: 129 PTLQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIED 308
PT++LS G +P++ +GTW KG+ + AV A+E GY +DTA YG E+
Sbjct: 9 PTVELSGGTRMPMLGMGTW---PLKGE------ECRAAVASAIEQGYRLVDTAEAYGNEE 59
Query: 309 QVGRALTKKFSEGLKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPI 488
VG+A+ + G R IF+TTK +H R+ V AL SLE L L+YVDL+L+HWP+
Sbjct: 60 AVGKAVREA---GPDRAEIFVTTKFSKQWHSRKGVHEALEHSLERLGLDYVDLFLMHWPM 116
Query: 489 AMFENDTLLDNVDFLDTWRGMIDAKKLGLTKS 584
++D +RGM++ K+ GL K+
Sbjct: 117 P--------GEGSYVDAYRGMVELKEQGLAKA 140
>UniRef50_Q1U9L6 Cluster: 2,5-didehydrogluconate reductase; n=3;
Lactobacillus|Rep: 2,5-didehydrogluconate reductase -
Lactobacillus reuteri 100-23
Length = 288
Score = 101 bits (241), Expect = 4e-20
Identities = 60/144 (41%), Positives = 81/144 (56%), Gaps = 2/144 (1%)
Frame = +3
Query: 132 TLQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQ 311
T L++G IP V GT+ R V EQAV A+E GY HIDTA YG E+
Sbjct: 10 TFNLNNGVKIPCVGYGTF---RTPADVA------EQAVKEAIETGYRHIDTAAVYGNEEA 60
Query: 312 VGRALTKKFSEGLKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPI- 488
VG+ + G+KRE +F+T+KLWN+ EQ A +++L+ L ++Y+DLYLIHWP
Sbjct: 61 VGKGIK---DSGIKREDLFVTSKLWNTNRGYEQTKKAFQETLDRLQMDYLDLYLIHWPAN 117
Query: 489 -AMFENDTLLDNVDFLDTWRGMID 557
F +D N +TWR M D
Sbjct: 118 EKQFGDDAAKINA---ETWRAMED 138
>UniRef50_Q03TW0 Cluster: Aldo/keto reductase of diketogulonate
reductase family; n=1; Lactobacillus brevis ATCC
367|Rep: Aldo/keto reductase of diketogulonate reductase
family - Lactobacillus brevis (strain ATCC 367 / JCM
1170)
Length = 293
Score = 101 bits (241), Expect = 4e-20
Identities = 60/166 (36%), Positives = 87/166 (52%)
Frame = +3
Query: 126 VPTLQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIE 305
+P L +++G IP + LG + V DT+ A+ +AL AGY HIDTA YG E
Sbjct: 11 IPDLPMNNGHQIPQLGLGVFQ--------VDNAEDTKNAIKWALAAGYRHIDTAAYYGNE 62
Query: 306 DQVGRALTKKFSEGLKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWP 485
VG A+ + + R+ IF+T+KLWNS ++ A +++L+ L L+Y+DLYLIHWP
Sbjct: 63 QWVGEAIRES---DVPRDQIFVTSKLWNSVRGYDETQAAFQETLDKLGLDYLDLYLIHWP 119
Query: 486 IAMFENDTLLDNVDFLDTWRGMIDAKKLGLTKS*ASPTLTRTNPED 623
+LD+WR M D K G K+ +T D
Sbjct: 120 AP-----------GYLDSWRAMEDLYKAGKIKNIGVSNFNQTQMAD 154
>UniRef50_A5KSS3 Cluster: Aldehyde reductase; n=1; candidate
division TM7 genomosp. GTL1|Rep: Aldehyde reductase -
candidate division TM7 genomosp. GTL1
Length = 299
Score = 101 bits (241), Expect = 4e-20
Identities = 61/161 (37%), Positives = 88/161 (54%), Gaps = 11/161 (6%)
Frame = +3
Query: 135 LQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQV 314
L L + +P++ GTW P G T V A++AGY HID A YG E +V
Sbjct: 4 LTLRNKQTLPLLGYGTW--ELPTGT-------TADLVETAIKAGYRHIDCAMIYGNEKEV 54
Query: 315 GRALTKKFSEGL-KRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPIA 491
G + + +G+ KRE +F+T+KLWN+ H + V A RK+L +L L+Y+DLYLIHW +A
Sbjct: 55 GEGIRRTIDQGVVKREDLFVTSKLWNTDHAQVDVGVACRKTLNDLGLDYLDLYLIHWGVA 114
Query: 492 MFENDTL--LDN--------VDFLDTWRGMIDAKKLGLTKS 584
D L LD+ + +TW+ M + + GL KS
Sbjct: 115 FEHGDNLEPLDDDGVAKFSFISMKETWQAMEELVEQGLVKS 155
>UniRef50_Q5KI95 Cluster: Aldo-keto reductase, putative; n=14;
Dikarya|Rep: Aldo-keto reductase, putative -
Cryptococcus neoformans (Filobasidiella neoformans)
Length = 353
Score = 101 bits (241), Expect = 4e-20
Identities = 57/136 (41%), Positives = 82/136 (60%), Gaps = 1/136 (0%)
Frame = +3
Query: 105 FTSADLIVPT-LQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHID 281
F S + PT +L++G +IP + LGTW + K +V QAV +AL+AGY HID
Sbjct: 28 FNSLIMSAPTSFKLNTGASIPAIGLGTW-----QAKAGEV----RQAVAHALKAGYRHID 78
Query: 282 TAYKYGIEDQVGRALTKKFSEGLKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYV 461
A Y ED+VG + G+ R IF+T+K+W+SYH+R V L +L++L +Y+
Sbjct: 79 GALCYQNEDEVGLGIK---DSGVPRSEIFLTSKVWSSYHDR--VEECLDTTLKSLQTDYL 133
Query: 462 DLYLIHWPIAMFENDT 509
DLYLIHWP+ + N T
Sbjct: 134 DLYLIHWPVRLAPNGT 149
>UniRef50_Q7QVQ9 Cluster: GLP_302_44328_45269; n=1; Giardia lamblia
ATCC 50803|Rep: GLP_302_44328_45269 - Giardia lamblia
ATCC 50803
Length = 313
Score = 100 bits (240), Expect = 5e-20
Identities = 54/131 (41%), Positives = 74/131 (56%), Gaps = 15/131 (11%)
Frame = +3
Query: 234 EQAVIYALEAGYTHIDTAYKYGIEDQVGRALTKKF---SEGLKRESIFITTKLWNSYHER 404
+ AV AL GY HID AY Y E+ +GRA K F S G+KRE ++IT+KLWN H
Sbjct: 20 QTAVETALMTGYRHIDCAYVYQNEEAIGRAFGKIFKDASSGIKREDVWITSKLWNYNHRP 79
Query: 405 EQVIPALRKSLENLNLEYVDLYLIHWPIAMFEND------------TLLDNVDFLDTWRG 548
E V +K++ +L ++Y+DL+L+HWP+A ND +L+ V DTWR
Sbjct: 80 ELVREQCKKTMSDLQVDYLDLFLVHWPLAFVRNDVGDLFPKDAEGRAMLEKVPLADTWRA 139
Query: 549 MIDAKKLGLTK 581
M + GL K
Sbjct: 140 MEQLVEEGLVK 150
>UniRef50_Q5T2L2 Cluster: Aldo-keto reductase family 1 member C-like
protein 1; n=14; Eutheria|Rep: Aldo-keto reductase
family 1 member C-like protein 1 - Homo sapiens (Human)
Length = 302
Score = 100 bits (240), Expect = 5e-20
Identities = 58/161 (36%), Positives = 92/161 (57%), Gaps = 13/161 (8%)
Frame = +3
Query: 132 TLQLSSGGNIPVVALGTWL-GHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIED 308
+++L+ G +PV+ GT+ H PK + + T A++ G+ HID+AY Y E+
Sbjct: 10 SVRLNDGPFMPVLGFGTYAPDHTPKSQAAEATK-------VAIDVGFRHIDSAYLYQNEE 62
Query: 309 QVGRALTKKFSEG-LKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWP 485
+VG+A+ +K ++G +KRE IF T KLW ++ E V PAL +SL+ L +YVDL++IH P
Sbjct: 63 EVGQAIWEKIADGTVKREEIFYTIKLWATFFRAELVHPALERSLKKLGPDYVDLFIIHVP 122
Query: 486 IAMFE-----------NDTLLDNVDFLDTWRGMIDAKKLGL 575
AM + + +L+ V+ DTW + K GL
Sbjct: 123 FAMKQPGKELLPKDASGEIILETVELCDTWELELILNKPGL 163
>UniRef50_A3LTU8 Cluster: D-arabinose dehydrogenase; n=5;
Saccharomycetales|Rep: D-arabinose dehydrogenase -
Pichia stipitis (Yeast)
Length = 326
Score = 100 bits (239), Expect = 7e-20
Identities = 53/119 (44%), Positives = 77/119 (64%), Gaps = 1/119 (0%)
Frame = +3
Query: 141 LSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQVGR 320
LS+G IP + LGT P ++ ++ VI A++AGY HIDTA+ YG E+ +G+
Sbjct: 12 LSNGKTIPALGLGTVPPEDP--------HELKEQVITAVKAGYRHIDTAWYYGTEEYIGQ 63
Query: 321 ALTKKFSEGL-KRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPIAM 494
AL + F EG+ KRE +FITTK+W S+ + +L KSL +L L+YVDL+L HWP+ +
Sbjct: 64 ALKQLFEEGIVKREDLFITTKVWPSFWRNPE--KSLDKSLADLGLDYVDLFLQHWPVVL 120
>UniRef50_Q7G764 Cluster: Probable NAD(P)H-dependent oxidoreductase
1; n=32; Eukaryota|Rep: Probable NAD(P)H-dependent
oxidoreductase 1 - Oryza sativa subsp. japonica (Rice)
Length = 321
Score = 100 bits (239), Expect = 7e-20
Identities = 49/131 (37%), Positives = 76/131 (58%), Gaps = 10/131 (7%)
Frame = +3
Query: 222 TNDTEQAVIYALEAGYTHIDTAYKYGIEDQVGRALTKKFSEGL--KRESIFITTKLWNSY 395
+ DT A++ A+E GY H DTA Y E VG A+ + GL R +F+T+K+W S
Sbjct: 31 SEDTTAAMLRAIELGYRHFDTARIYATEGCVGEAVAEAVRRGLIASRADVFVTSKIWCSD 90
Query: 396 HEREQVIPALRKSLENLNLEYVDLYLIHWPIAM--------FENDTLLDNVDFLDTWRGM 551
+V+PA R++L NL ++YVDL L+HWP+++ F + +L + D WRGM
Sbjct: 91 LHAGRVVPAARETLRNLGMDYVDLLLVHWPVSLTPGNYDFPFPKEVILPSFDMEGVWRGM 150
Query: 552 IDAKKLGLTKS 584
+ +LGL ++
Sbjct: 151 EECHRLGLARA 161
>UniRef50_Q9ZUJ6 Cluster: T2K10.1 protein; n=16; core
eudicotyledons|Rep: T2K10.1 protein - Arabidopsis
thaliana (Mouse-ear cress)
Length = 176
Score = 99 bits (238), Expect = 9e-20
Identities = 60/166 (36%), Positives = 93/166 (56%), Gaps = 14/166 (8%)
Frame = +3
Query: 126 VPTLQLSSGGN----IPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYK 293
VPTL + SG + +PV+ GT P+ +++ T VI A++ GY H DT+ +
Sbjct: 6 VPTLAIRSGPSGHHSMPVLGFGTAASPLPEPTMLKET------VIEAIKLGYRHFDTSPR 59
Query: 294 YGIEDQVGRALTKKFSEGL--KRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDL 467
Y E+ +G AL + S GL R F+TTKLW + V+PA+++SL+NL L+Y+DL
Sbjct: 60 YQTEEPIGEALAEAVSLGLVRSRSEFFVTTKLWCADAHGGLVVPAIKRSLKNLKLDYLDL 119
Query: 468 YLIHWPIAM--------FENDTLLDNVDFLDTWRGMIDAKKLGLTK 581
Y+IHWP++ + D + +DF W M + ++LGL K
Sbjct: 120 YIIHWPVSSKPGKYKFPIDEDDFMP-MDFEVVWSEMEECQRLGLAK 164
>UniRef50_P23901 Cluster: Aldose reductase; n=9; Poaceae|Rep: Aldose
reductase - Hordeum vulgare (Barley)
Length = 320
Score = 99.5 bits (237), Expect = 1e-19
Identities = 56/154 (36%), Positives = 85/154 (55%), Gaps = 7/154 (4%)
Frame = +3
Query: 141 LSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYAL-EAGYTHIDTAYKYGIEDQVG 317
L SG +P V LGTW + +DT +V A+ EAGY H+DTA +YG+E +VG
Sbjct: 18 LKSGHAMPAVGLGTW----------RAGSDTAHSVRTAITEAGYRHVDTAAEYGVEKEVG 67
Query: 318 RALTKKFSEGLKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPIAMF 497
+ L G+ R+ +F+T+K+W + E+V PAL +L++L L+Y+DLY IHWP +
Sbjct: 68 KGLKAAMEAGIDRKDLFVTSKIWCTNLAPERVRPALENTLKDLQLDYIDLYHIHWPFRLK 127
Query: 498 ENDTL------LDNVDFLDTWRGMIDAKKLGLTK 581
+ + + D W+ M + K GL K
Sbjct: 128 DGAHMPPEAGEVLEFDMEGVWKEMENLVKDGLVK 161
>UniRef50_P22045 Cluster: Probable reductase; n=101; cellular
organisms|Rep: Probable reductase - Leishmania major
Length = 284
Score = 99.1 bits (236), Expect = 2e-19
Identities = 57/135 (42%), Positives = 77/135 (57%)
Frame = +3
Query: 141 LSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQVGR 320
LS+G +P LG W P G+V TE AV +AL AGY HIDTA Y E+ VG
Sbjct: 11 LSNGVKMPQFGLGVW--QSPAGEV------TENAVNWALCAGYRHIDTAAIYKNEESVGA 62
Query: 321 ALTKKFSEGLKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPIAMFE 500
L + G+ RE +FITTKLWN+ E + A +S + L ++Y+DLYLIHWP +
Sbjct: 63 GLR---ASGVPREDVFITTKLWNTEQGYESTLAAFEESRQKLGVDYIDLYLIHWPRG--K 117
Query: 501 NDTLLDNVDFLDTWR 545
+ + +LD+WR
Sbjct: 118 DILSKEGKKYLDSWR 132
>UniRef50_Q0IBY6 Cluster: Alcohol dehydrogenase; n=2;
Chroococcales|Rep: Alcohol dehydrogenase - Synechococcus
sp. (strain CC9311)
Length = 336
Score = 98.7 bits (235), Expect = 2e-19
Identities = 59/166 (35%), Positives = 93/166 (56%), Gaps = 13/166 (7%)
Frame = +3
Query: 123 IVPTLQ---LSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYK 293
++PT+Q LS+G +P++ LGT K + QV +A+ + GY HID A
Sbjct: 15 VIPTMQYASLSNGDRMPLLGLGTG-----KSESRQVYKSVREAI----KIGYRHIDCASI 65
Query: 294 YGIEDQVGRALTKKF-SEGLKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLY 470
YG E++VG A+ + + R ++IT+KLW++ H + V AL +SL+NL ++Y++LY
Sbjct: 66 YGNEEEVGDAIRDAIQNHEITRSELWITSKLWSNCHGKNHVEAALSQSLQNLGVDYLNLY 125
Query: 471 LIHWPIAMFENDTLLDNVDFL---------DTWRGMIDAKKLGLTK 581
LIHWP+ + T ++VD L +TW M + GLTK
Sbjct: 126 LIHWPVGIRPEKTFAESVDDLLTPEESPISETWEAMESTRDKGLTK 171
>UniRef50_Q2V420 Cluster: Uncharacterized protein At2g37770.1; n=1;
Arabidopsis thaliana|Rep: Uncharacterized protein
At2g37770.1 - Arabidopsis thaliana (Mouse-ear cress)
Length = 283
Score = 98.7 bits (235), Expect = 2e-19
Identities = 60/145 (41%), Positives = 82/145 (56%), Gaps = 7/145 (4%)
Frame = +3
Query: 138 QLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQVG 317
+L++G P V LGTW G V AV A++ GY HID A YG E ++G
Sbjct: 9 KLNTGAKFPSVGLGTW--QASPGLV-------GDAVAAAVKIGYRHIDCAQIYGNEKEIG 59
Query: 318 RALTKKFSEGL-KRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPIAM 494
L K F + + KRE +FIT+KLW + H+ + V AL ++L++L LEYVDLYLIHWP +
Sbjct: 60 AVLKKLFEDRVVKREDLFITSKLWCTDHDPQDVPEALNRTLKDLQLEYVDLYLIHWPARI 119
Query: 495 ------FENDTLLDNVDFLDTWRGM 551
+ + LL VD TW+ M
Sbjct: 120 KKGSVGIKPENLLP-VDIPSTWKAM 143
>UniRef50_Q0PGJ6 Cluster: Aldo-keto reductase; n=32;
Magnoliophyta|Rep: Aldo-keto reductase - Arabidopsis
thaliana (Mouse-ear cress)
Length = 315
Score = 98.7 bits (235), Expect = 2e-19
Identities = 60/145 (41%), Positives = 82/145 (56%), Gaps = 7/145 (4%)
Frame = +3
Query: 138 QLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQVG 317
+L++G P V LGTW G V AV A++ GY HID A YG E ++G
Sbjct: 9 KLNTGAKFPSVGLGTW--QASPGLV-------GDAVAAAVKIGYRHIDCAQIYGNEKEIG 59
Query: 318 RALTKKFSEGL-KRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPIAM 494
L K F + + KRE +FIT+KLW + H+ + V AL ++L++L LEYVDLYLIHWP +
Sbjct: 60 AVLKKLFEDRVVKREDLFITSKLWCTDHDPQDVPEALNRTLKDLQLEYVDLYLIHWPARI 119
Query: 495 ------FENDTLLDNVDFLDTWRGM 551
+ + LL VD TW+ M
Sbjct: 120 KKGSVGIKPENLLP-VDIPSTWKAM 143
>UniRef50_UPI0000498F1F Cluster: oxidoreductase, aldo/keto reductase
family; n=2; Entamoeba histolytica HM-1:IMSS|Rep:
oxidoreductase, aldo/keto reductase family - Entamoeba
histolytica HM-1:IMSS
Length = 305
Score = 98.3 bits (234), Expect = 3e-19
Identities = 56/151 (37%), Positives = 85/151 (56%), Gaps = 3/151 (1%)
Frame = +3
Query: 141 LSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQVGR 320
L++G IP + LGTW+ + +AV A++ GY HID A YG E +VG
Sbjct: 7 LNNGYKIPKLGLGTWMS---------ANGEVGKAVEIAIKNGYRHIDCAKAYGNEKEVGD 57
Query: 321 ALTKKFSEG-LKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPIAMF 497
+ ++G +KRE +F+TTKLW++ +E V PA +SL+ L LEY+DLY+IH P+
Sbjct: 58 GIKSAIAKGYVKREELFVTTKLWSTDKHKEDVRPACLESLKKLQLEYLDLYIIHIPLTAD 117
Query: 498 E--NDTLLDNVDFLDTWRGMIDAKKLGLTKS 584
+ + + + +TWR M + GL KS
Sbjct: 118 KKTGEFTEEIIPIEETWREMEKLVEEGLVKS 148
>UniRef50_Q7PLK6 Cluster: CG40064-PA; n=1; Drosophila
melanogaster|Rep: CG40064-PA - Drosophila melanogaster
(Fruit fly)
Length = 361
Score = 98.3 bits (234), Expect = 3e-19
Identities = 51/127 (40%), Positives = 73/127 (57%), Gaps = 12/127 (9%)
Frame = +3
Query: 240 AVIYALEAGYTHIDTAYKYGIEDQVGRALTKKFSEG-LKRESIFITTKLWNSYHEREQVI 416
AV A+E G+ H DTAY Y E ++G AL + G + RE+IF+TTKLWN++H+ V
Sbjct: 49 AVHCAIETGFRHFDTAYYYENEKEIGEALRTQIKMGNISRENIFLTTKLWNTHHDPRDVR 108
Query: 417 PALRKSLENLNLEYVDLYLIHWPIA-----------MFENDTLLDNVDFLDTWRGMIDAK 563
K LE L Y+DLYL+H+P+ M ++ +D+LDTWR M +
Sbjct: 109 RICEKQLELLGFSYIDLYLMHFPVGYKYVCDEILMPMSGDELQTVEIDYLDTWRAMENLV 168
Query: 564 KLGLTKS 584
KLG+ +S
Sbjct: 169 KLGMVRS 175
>UniRef50_Q9HGY0 Cluster: Glycerol dehydrogenase; n=8;
Saccharomycetaceae|Rep: Glycerol dehydrogenase -
Zygosaccharomyces rouxii (Candida mogii)
Length = 310
Score = 97.9 bits (233), Expect = 4e-19
Identities = 56/121 (46%), Positives = 75/121 (61%)
Frame = +3
Query: 132 TLQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQ 311
TL+L++G IP V LGTW R K N+ +AVI AL+AGY HID A YG E +
Sbjct: 10 TLKLNTGQTIPQVGLGTW---RSK------ENEGYKAVIEALKAGYRHIDGAAVYGNEGE 60
Query: 312 VGRALTKKFSEGLKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPIA 491
VG+A+ G+ R IF+TTKLW ++ Q AL +SL+ L L+YV LYL+HWP+
Sbjct: 61 VGKAIQ---DSGVPRNEIFLTTKLWCTHQRNPQ--EALDQSLQRLGLDYVGLYLVHWPVP 115
Query: 492 M 494
+
Sbjct: 116 L 116
>UniRef50_Q83N50 Cluster: 2,5-diketo-D-gluconic acid reductase; n=2;
Tropheryma whipplei|Rep: 2,5-diketo-D-gluconic acid
reductase - Tropheryma whipplei (strain Twist)
(Whipple's bacillus)
Length = 283
Score = 97.5 bits (232), Expect = 5e-19
Identities = 61/153 (39%), Positives = 84/153 (54%)
Frame = +3
Query: 126 VPTLQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIE 305
VP++ L G +IP LGT+ P N+ V A+E GY HIDTA Y E
Sbjct: 9 VPSVLLGDGVSIPQFGLGTY--ELPP-------NEASSVVQSAIELGYRHIDTASLYANE 59
Query: 306 DQVGRALTKKFSEGLKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWP 485
+VGRA+ S G+KRE F+TTKLWNS + + A +SL+ L+L+YVDLYLIHWP
Sbjct: 60 REVGRAIA---SSGIKREEFFVTTKLWNSDQPKPR--EAFERSLDLLSLDYVDLYLIHWP 114
Query: 486 IAMFENDTLLDNVDFLDTWRGMIDAKKLGLTKS 584
E +++ W +++ K+ G KS
Sbjct: 115 CPPSEL--------YINVWEVLLELKESGRAKS 139
>UniRef50_Q9ZBW7 Cluster: Putative oxidoreductase; n=2;
Actinomycetales|Rep: Putative oxidoreductase -
Streptomyces coelicolor
Length = 277
Score = 96.7 bits (230), Expect = 8e-19
Identities = 55/122 (45%), Positives = 71/122 (58%), Gaps = 1/122 (0%)
Frame = +3
Query: 126 VPTLQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQ-AVIYALEAGYTHIDTAYKYGI 302
VP + L++G +P + G W QV +D Q AV ALEAGY IDTA YG
Sbjct: 5 VPPIILNNGVEMPQLGFGVW----------QVPDDDAQTAVALALEAGYRSIDTAAIYGN 54
Query: 303 EDQVGRALTKKFSEGLKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHW 482
E+ GRA+ + GL RE +F+TTKLWNS + + A S+ L LEY+DLYLIHW
Sbjct: 55 EEGTGRAIA---ASGLAREDLFVTTKLWNSDQGYDSTLRAFDTSMAKLGLEYLDLYLIHW 111
Query: 483 PI 488
P+
Sbjct: 112 PM 113
>UniRef50_A1UEC5 Cluster: 2,5-didehydrogluconate reductase; n=20;
Corynebacterineae|Rep: 2,5-didehydrogluconate reductase
- Mycobacterium sp. (strain KMS)
Length = 283
Score = 96.7 bits (230), Expect = 8e-19
Identities = 61/153 (39%), Positives = 89/153 (58%)
Frame = +3
Query: 126 VPTLQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIE 305
+P++ L+ G +IPV+ LG G++ + + E++V ALEAGY IDTA YG E
Sbjct: 11 IPSVSLNDGHSIPVLGLGV-------GELSEA--EAERSVAAALEAGYRLIDTAAVYGNE 61
Query: 306 DQVGRALTKKFSEGLKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWP 485
VGRA+ + G+ RE I++TTKL + A R SLE L L+YVDLYLIHWP
Sbjct: 62 AAVGRAVN---ASGIPREEIYVTTKLAVADQGFGTSQDAARASLERLGLDYVDLYLIHWP 118
Query: 486 IAMFENDTLLDNVDFLDTWRGMIDAKKLGLTKS 584
D+ ++D+W G++ AK+ G+ +S
Sbjct: 119 AG--------DHGKYIDSWGGLMKAKQDGVARS 143
>UniRef50_A4RQH8 Cluster: Predicted protein; n=2; Ostreococcus|Rep:
Predicted protein - Ostreococcus lucimarinus CCE9901
Length = 337
Score = 96.7 bits (230), Expect = 8e-19
Identities = 53/117 (45%), Positives = 67/117 (57%), Gaps = 1/117 (0%)
Frame = +3
Query: 144 SSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQVGRA 323
++G IP V LGTW RP N+ AV AL AGY H+D A Y E +VG A
Sbjct: 11 ANGLRIPRVGLGTWKA-RP--------NEVRDAVRDALGAGYAHVDCAAAYANESEVGEA 61
Query: 324 LTKKFSEG-LKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPIA 491
L + F G KRE +F+T+KLWN V AL +L +L + Y+DLYLIHWP+A
Sbjct: 62 LREAFERGDAKREDVFVTSKLWNDRRRPRDVREALMTTLNDLGVGYLDLYLIHWPVA 118
>UniRef50_Q6RZX1 Cluster: Gld1; n=22; Pezizomycotina|Rep: Gld1 -
Trichoderma atroviride (Hypocrea atroviridis)
Length = 327
Score = 96.7 bits (230), Expect = 8e-19
Identities = 51/126 (40%), Positives = 73/126 (57%), Gaps = 2/126 (1%)
Frame = +3
Query: 132 TLQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQ 311
T L++G IP V GT+ KG +T AV AL+ GY H+D A+ Y ED+
Sbjct: 14 TYTLNTGAKIPAVGFGTFANEGAKG-------ETYAAVTKALDVGYRHLDCAWFYLNEDE 66
Query: 312 VGRALTKKFSE--GLKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWP 485
VG A+ + + R+ +FI TK+WN HE E V + + S ENL ++Y+DL+L+HWP
Sbjct: 67 VGDAIRDFLARRPDVTRKDLFICTKVWNHLHEPEDVKWSAKNSCENLKVDYIDLFLVHWP 126
Query: 486 IAMFEN 503
IA +N
Sbjct: 127 IAAEKN 132
>UniRef50_A7CWF9 Cluster: Aldehyde reductase; n=2; Bacteria|Rep:
Aldehyde reductase - Opitutaceae bacterium TAV2
Length = 347
Score = 96.3 bits (229), Expect = 1e-18
Identities = 50/127 (39%), Positives = 70/127 (55%), Gaps = 3/127 (2%)
Frame = +3
Query: 126 VPTLQLSSGGNIPVVALGTW-LGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGI 302
+P L+SG +P + +GT+ H G+V +V A E GY H D A Y
Sbjct: 16 IPQRTLASGARMPAIGMGTFGSDHAAPGEVAA-------SVYAAAELGYRHFDCAAVYSN 68
Query: 303 EDQVGRALTKKFSE--GLKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLI 476
E ++G + + G++RE ++IT+KLWN H VIPA KSL +L L+Y+DLYLI
Sbjct: 69 EREIGATFRRILTSNTGIRREDLWITSKLWNDKHAEADVIPAFEKSLRDLGLDYLDLYLI 128
Query: 477 HWPIAMF 497
HWP F
Sbjct: 129 HWPFPNF 135
>UniRef50_A3C1Z7 Cluster: Putative uncharacterized protein; n=2;
Oryza sativa (japonica cultivar-group)|Rep: Putative
uncharacterized protein - Oryza sativa subsp. japonica
(Rice)
Length = 288
Score = 96.3 bits (229), Expect = 1e-18
Identities = 59/165 (35%), Positives = 92/165 (55%), Gaps = 12/165 (7%)
Frame = +3
Query: 126 VPTLQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIE 305
+P LSSG +P V +GT P G T + V+ A+EAGY H DTA Y E
Sbjct: 1 MPEAALSSGKPMPRVGMGT--ASFPLGATDPST--VKDVVLRAIEAGYRHFDTAAVYQTE 56
Query: 306 DQVGRALTKKFSEGL--KRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIH 479
+G A+ + GL R+ ++IT+KLW ++ V+P+LR++L + +EY+DLYLIH
Sbjct: 57 AILGDAVAEAVRAGLVASRDELYITSKLWVAHAHPGHVLPSLRRALRKMQMEYLDLYLIH 116
Query: 480 WPIAM----------FENDTLLDNVDFLDTWRGMIDAKKLGLTKS 584
+P++M + D L+ +D W+ M + ++LGLTK+
Sbjct: 117 FPVSMRLAEDPESMTYSKDDLV-MMDMEGVWKEMEECQRLGLTKA 160
>UniRef50_Q16K66 Cluster: Aldo-keto reductase; n=2; Aedes
aegypti|Rep: Aldo-keto reductase - Aedes aegypti
(Yellowfever mosquito)
Length = 303
Score = 96.3 bits (229), Expect = 1e-18
Identities = 62/158 (39%), Positives = 92/158 (58%), Gaps = 8/158 (5%)
Frame = +3
Query: 135 LQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQV 314
L L++G +IP + LGT+ K+ +D A+ A+E GY IDTA+ Y E V
Sbjct: 2 LALNNGHSIPPIGLGTY-------KITG--SDGVAAIKSAVEFGYRLIDTAFVYNNEQVV 52
Query: 315 GRALTKKFSEG--LKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPI 488
G+AL + FS+G + RE +FI +KL ++H E V R SLE L L+YVDLYL+H P+
Sbjct: 53 GQALREIFSQGNDINREDVFIVSKLGPTFHRPEAVEKGCRLSLERLGLDYVDLYLMHTPV 112
Query: 489 AMFE----ND--TLLDNVDFLDTWRGMIDAKKLGLTKS 584
A + ND + D V L+TW+ + + ++ GL +S
Sbjct: 113 AARDSGDGNDRSEIDDEVTPLETWKALEECQRKGLVRS 150
>UniRef50_Q8F1G4 Cluster: Aldehyde reductase; n=8; Bacteria|Rep:
Aldehyde reductase - Leptospira interrogans
Length = 278
Score = 95.9 bits (228), Expect = 1e-18
Identities = 52/126 (41%), Positives = 78/126 (61%)
Frame = +3
Query: 132 TLQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQ 311
T+ L++G ++P++ LG W GK + ++AV+ ALEAGY HIDTA Y E
Sbjct: 11 TIMLNNGISMPILGLGVW--KTKSGK------ECKEAVLNALEAGYRHIDTARIYDNEVD 62
Query: 312 VGRALTKKFSEGLKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPIA 491
VG+A+ + G+ R+ IFITTKLWN+ ++ AL SL+ L +++VDLYLIH+P+
Sbjct: 63 VGQAIRES---GIPRKEIFITTKLWNADQGSDKTRKALENSLDRLGIDFVDLYLIHFPVT 119
Query: 492 MFENDT 509
D+
Sbjct: 120 SKRMDS 125
>UniRef50_A2FPE2 Cluster: Oxidoreductase, aldo/keto reductase family
protein; n=3; Trichomonas vaginalis G3|Rep:
Oxidoreductase, aldo/keto reductase family protein -
Trichomonas vaginalis G3
Length = 309
Score = 95.9 bits (228), Expect = 1e-18
Identities = 54/154 (35%), Positives = 88/154 (57%), Gaps = 13/154 (8%)
Frame = +3
Query: 159 IPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQVGRALTKKF 338
IP + LGT+L P V + E ++GY H+D A Y ++ +G AL++ F
Sbjct: 4 IPSIGLGTFLAEDPAALKAAVHSAIE-------DSGYRHVDCAAYYKNQEIIGEALSEIF 56
Query: 339 SEG-LKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPIAM--FENDT 509
++G +KRE ++IT+K+WN+ H + ++ ++K+L+ L LEY+DL L+HW A E+D
Sbjct: 57 AKGQVKREEVWITSKVWNTKHRPDLLVKDVKKTLKELKLEYLDLVLVHWACAFQSREDDE 116
Query: 510 LL----------DNVDFLDTWRGMIDAKKLGLTK 581
L +N+D L+TW+ M + LGL K
Sbjct: 117 YLPRDETGKIITENIDILETWKAMEECYNLGLAK 150
>UniRef50_Q7ZA52 Cluster: Aldose reductase; n=6; Pezizomycotina|Rep:
Aldose reductase - Magnaporthe grisea (Rice blast
fungus) (Pyricularia grisea)
Length = 312
Score = 95.9 bits (228), Expect = 1e-18
Identities = 51/119 (42%), Positives = 76/119 (63%), Gaps = 1/119 (0%)
Frame = +3
Query: 141 LSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQVGR 320
L++G IP LGTW G KG + ++AV+ A+++GY ID AY YG E++VG+
Sbjct: 8 LNTGAKIPAFGLGTWQGD--KGVI-------KEAVLTAIKSGYRLIDGAYVYGNEEEVGQ 58
Query: 321 ALTKKFSEGL-KRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPIAM 494
+ + S G+ KRE +F+ +K W +Y R ++ L +SL+ L L+YVDLYL+HWPI M
Sbjct: 59 GIREAISSGIVKREDLFVVSKCWATYTTRCEL--GLDQSLKLLGLDYVDLYLVHWPILM 115
>UniRef50_A1D4E3 Cluster: D-xylose reductase (Xyl1), putative; n=5;
Pezizomycotina|Rep: D-xylose reductase (Xyl1), putative
- Neosartorya fischeri (strain ATCC 1020 / DSM 3700 /
NRRL 181)(Aspergillus fischerianus (strain ATCC 1020 /
DSM 3700 / NRRL 181))
Length = 321
Score = 95.9 bits (228), Expect = 1e-18
Identities = 49/127 (38%), Positives = 78/127 (61%), Gaps = 2/127 (1%)
Frame = +3
Query: 120 LIVPTLQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIY-ALEAGYTHIDTAYKY 296
+ P+ +L+SG ++P+V G W +V N+T IY A++AGY D A Y
Sbjct: 1 MTTPSTKLNSGYDMPLVGFGLW----------KVNNETCADQIYHAIKAGYRLFDGACDY 50
Query: 297 GIEDQVGRALTKKFSEGL-KRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYL 473
G E + G+ + + EG+ KRE +FI +KLWNS+H+ ++V P RK L + L+Y DL++
Sbjct: 51 GNEVEAGKGVARAIQEGIVKREDLFIVSKLWNSFHDGDRVEPICRKQLADWGLDYFDLFI 110
Query: 474 IHWPIAM 494
+H+PIA+
Sbjct: 111 VHFPIAL 117
>UniRef50_UPI0000E45E29 Cluster: PREDICTED: similar to aldose
reductase; n=1; Strongylocentrotus purpuratus|Rep:
PREDICTED: similar to aldose reductase -
Strongylocentrotus purpuratus
Length = 274
Score = 95.1 bits (226), Expect = 3e-18
Identities = 46/87 (52%), Positives = 59/87 (67%), Gaps = 1/87 (1%)
Frame = +3
Query: 234 EQAVIYALEAGYTHIDTAYKYGIEDQVGRALTKKFSEGL-KRESIFITTKLWNSYHEREQ 410
E AV A++ GY HID A+ YG E +VG L +KF + KRE IFIT+KLWN+ H +
Sbjct: 13 EAAVKAAIDCGYRHIDCAHVYGNEAEVGAGLKEKFDANVVKREDIFITSKLWNNKHHPDD 72
Query: 411 VIPALRKSLENLNLEYVDLYLIHWPIA 491
V A +L+NL L YVDLYL+HWP+A
Sbjct: 73 VEQACDITLKNLQLSYVDLYLMHWPMA 99
>UniRef50_P51857 Cluster: 3-oxo-5-beta-steroid 4-dehydrogenase (EC
1.3.1.3) (Delta(4)-3- ketosteroid 5-beta-reductase);
n=124; cellular organisms|Rep: 3-oxo-5-beta-steroid
4-dehydrogenase (EC 1.3.1.3) (Delta(4)-3- ketosteroid
5-beta-reductase) - Homo sapiens (Human)
Length = 326
Score = 94.7 bits (225), Expect = 3e-18
Identities = 61/161 (37%), Positives = 85/161 (52%), Gaps = 11/161 (6%)
Frame = +3
Query: 135 LQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQV 314
+ LS G +IP++ LGT+ + K T+ V A++ GY HID AY Y E +V
Sbjct: 10 IPLSDGNSIPIIGLGTYSEPKSTPKGACATS-----VKVAIDTGYRHIDGAYIYQNEHEV 64
Query: 315 GRALTKKFSEG-LKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPIA 491
G A+ +K +EG ++RE IF KLW + H E V P L ++L L L+YVDLY+I P+A
Sbjct: 65 GEAIREKIAEGKVRREDIFYCGKLWATNHVPEMVRPTLERTLRVLQLDYVDLYIIEVPMA 124
Query: 492 MFENDTLL---DNVDFL-------DTWRGMIDAKKLGLTKS 584
D + +N +L TW M K GL KS
Sbjct: 125 FKPGDEIYPRDENGKWLYHKSNLCATWEAMEACKDAGLVKS 165
>UniRef50_Q8ET73 Cluster: 2,5-diketo-D-gluconate reductase; n=12;
Bacteria|Rep: 2,5-diketo-D-gluconate reductase -
Oceanobacillus iheyensis
Length = 280
Score = 94.3 bits (224), Expect = 4e-18
Identities = 64/182 (35%), Positives = 95/182 (52%), Gaps = 1/182 (0%)
Frame = +3
Query: 126 VPTLQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIE 305
+P + L G IP V GT+ R G ND QA+ A++ GY IDTAY Y E
Sbjct: 5 IPNVTLHDGLTIPKVGFGTY---RLNG------NDGVQAINNAIDHGYRLIDTAYNYENE 55
Query: 306 DQVGRALTKKFSEGLKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWP 485
VG A+ + + RE + IT+KL YH ++ + +++SL NL+Y DLYLIHWP
Sbjct: 56 GTVGEAVRRSSTP---REQLLITSKLPGRYHHYDKAVTTIQESLYRANLDYYDLYLIHWP 112
Query: 486 IAMFENDTLLDNVDFLDTWRGMIDAKKLGLTKS*ASPTLTRTNPEDHRQRTGEXSAL-QI 662
+ + D +++ W+ +I+AK+ G +S + E +Q TGE + QI
Sbjct: 113 ------NPIQD--IYVEAWQALIEAKRRGYIRSIGVCNFLPEHLERLKQETGELPTINQI 164
Query: 663 EL 668
EL
Sbjct: 165 EL 166
>UniRef50_Q68ST9 Cluster: Reductase AKOR2; n=2; Pleurotus
djamor|Rep: Reductase AKOR2 - Pleurotus djamor
Length = 306
Score = 94.3 bits (224), Expect = 4e-18
Identities = 53/128 (41%), Positives = 78/128 (60%), Gaps = 1/128 (0%)
Frame = +3
Query: 129 PTLQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIED 308
P + L++G +P +ALG W G + + ++ + AL++GY HIDTA Y E
Sbjct: 5 PPIVLNTGARMPALALGGWAGLTEEERT-----QAKEWFLTALKSGYRHIDTAQIYYTEK 59
Query: 309 QVGRALTKKFSEGLKRESIFITTKL-WNSYHEREQVIPALRKSLENLNLEYVDLYLIHWP 485
VG A+ + G+ RE +FITTKL WN +H R V + +KSLENL EY+DLYL+H+P
Sbjct: 60 SVGNAIRES---GIPREELFITTKLPWN-HHSR--VAESFQKSLENLGTEYIDLYLVHFP 113
Query: 486 IAMFENDT 509
+F ++T
Sbjct: 114 QRVFYDET 121
>UniRef50_A2QVE5 Cluster: Similarity: shows similarity to several
dehydrogenases of different specificities; n=4;
Pezizomycotina|Rep: Similarity: shows similarity to
several dehydrogenases of different specificities -
Aspergillus niger
Length = 381
Score = 94.3 bits (224), Expect = 4e-18
Identities = 58/160 (36%), Positives = 81/160 (50%), Gaps = 18/160 (11%)
Frame = +3
Query: 141 LSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQVGR 320
L+SG IP + GTW G+V AV AL+AGY H+D A Y + +V
Sbjct: 9 LNSGAQIPQLGFGTW--QSAPGQV-------GDAVYEALKAGYRHLDLATIYQNQREVAE 59
Query: 321 ALTKKFSE--GLKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPIAM 494
+ + + + GLKRE IFIT+KLWNS H+ V AL + L L L+Y+DLYL+HWP++
Sbjct: 60 GIKRAYKDVPGLKREDIFITSKLWNSQHDPAVVEKALDECLAELELDYLDLYLVHWPVSF 119
Query: 495 FENDTLL----------------DNVDFLDTWRGMIDAKK 566
L D++ +DTW+ M K
Sbjct: 120 TTGSELFPLVKDSSVEGGDVVINDDISIVDTWKAMTQLPK 159
>UniRef50_Q01HB5 Cluster: OSIGBa0136O08-OSIGBa0153H12.9 protein;
n=4; Oryza sativa|Rep: OSIGBa0136O08-OSIGBa0153H12.9
protein - Oryza sativa (Rice)
Length = 337
Score = 93.9 bits (223), Expect = 6e-18
Identities = 61/171 (35%), Positives = 86/171 (50%), Gaps = 13/171 (7%)
Frame = +3
Query: 111 SADLIVPTLQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAY 290
+A VP + L+SG +PV+ GT P D + +A+ GY H+DTA
Sbjct: 15 AAATAVPCVTLNSGHAMPVLGFGTGSSTPPA--------DLAATIAHAVRLGYRHLDTAA 66
Query: 291 KYGIEDQVGRALTKKFSEGL--KRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVD 464
YG E VG A+ + G R +F+TTKL + +V+ ALR+SL L L+YVD
Sbjct: 67 VYGTEGAVGAAVAEAVRCGAVASRGELFVTTKLSMADAHPPRVVAALRESLSRLGLDYVD 126
Query: 465 LYLIHWPIAMFENDTL-----------LDNVDFLDTWRGMIDAKKLGLTKS 584
L+LIHWP+A+ + D L D WRGM + +LGL +S
Sbjct: 127 LFLIHWPVAIGKKDAAGELTWDDLSRGLVPFDMEGVWRGMEECHRLGLARS 177
>UniRef50_Q10494 Cluster: Probable oxidoreductase C26F1.07; n=2;
Schizosaccharomyces pombe|Rep: Probable oxidoreductase
C26F1.07 - Schizosaccharomyces pombe (Fission yeast)
Length = 321
Score = 93.9 bits (223), Expect = 6e-18
Identities = 50/117 (42%), Positives = 70/117 (59%)
Frame = +3
Query: 141 LSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQVGR 320
L+ G IP + LGTW N T+ AV AL+ GY HID A YG ED+VG
Sbjct: 18 LADGSKIPGLGLGTWRSE---------PNQTKNAVKTALQYGYRHIDAAAIYGNEDEVGD 68
Query: 321 ALTKKFSEGLKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPIA 491
+ + G+ R+ I++T+KLW + H E V AL K+L++L L+Y+D YLIHWP++
Sbjct: 69 GIKES---GVPRKDIWVTSKLWCNAHAPEAVPKALEKTLKDLKLDYLDEYLIHWPVS 122
>UniRef50_Q7ZWA4 Cluster: Zgc:56622; n=6; cellular organisms|Rep:
Zgc:56622 - Danio rerio (Zebrafish) (Brachydanio rerio)
Length = 289
Score = 93.5 bits (222), Expect = 8e-18
Identities = 49/128 (38%), Positives = 74/128 (57%), Gaps = 11/128 (8%)
Frame = +3
Query: 234 EQAVIYALEAGYTHIDTAYKYGIEDQVGRALTKKFSEGL-KRESIFITTKLWNSYHEREQ 410
++A A+ AGY HIDTA+ Y E VG A+ K +G+ +R+ +FI +KLW ++H E
Sbjct: 3 QRACEAAIAAGYRHIDTAFCYRNEVDVGMAIQNKIQQGIIRRQDMFIVSKLWGTHHAPED 62
Query: 411 VIPALRKSLENLNLEYVDLYLIHWPIAMF--------END--TLLDNVDFLDTWRGMIDA 560
+ KSL +L L+Y+D YL+H+P+ + E D L ++D++D WRGM
Sbjct: 63 IPVCFNKSLSDLQLDYLDQYLVHFPVGLKKVGDELFPERDGKILTTDIDYVDVWRGMEAL 122
Query: 561 KKLGLTKS 584
K G KS
Sbjct: 123 KATGKVKS 130
>UniRef50_UPI000155CAC7 Cluster: PREDICTED: hypothetical protein;
n=1; Ornithorhynchus anatinus|Rep: PREDICTED:
hypothetical protein - Ornithorhynchus anatinus
Length = 419
Score = 93.1 bits (221), Expect = 1e-17
Identities = 59/145 (40%), Positives = 82/145 (56%), Gaps = 1/145 (0%)
Frame = +3
Query: 120 LIVPTLQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYAL-EAGYTHIDTAYKY 296
L VPT+ L++G NIP++ LGT H V + AVIYAL E G HIDTA +Y
Sbjct: 10 LPVPTVPLANGLNIPILGLGT--SH--------VGGYSHDAVIYALKECGIRHIDTAKRY 59
Query: 297 GIEDQVGRALTKKFSEGLKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLI 476
G E +G+A+ + G+KRE ++ITTKLW + + E + +S L +EY+DL+LI
Sbjct: 60 GCELLLGKAIQES---GVKREELWITTKLWLTDYGYESAKQSCLESCNRLGVEYLDLFLI 116
Query: 477 HWPIAMFENDTLLDNVDFLDTWRGM 551
HWP A + +TWR M
Sbjct: 117 HWPDAQLPGKS--SREARAETWRAM 139
>UniRef50_A0JRJ3 Cluster: 2,5-didehydrogluconate reductase; n=3;
Actinobacteria (class)|Rep: 2,5-didehydrogluconate
reductase - Arthrobacter sp. (strain FB24)
Length = 276
Score = 93.1 bits (221), Expect = 1e-17
Identities = 51/120 (42%), Positives = 68/120 (56%)
Frame = +3
Query: 129 PTLQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIED 308
P ++L+ G IP + LGTW P + AV+ A+E GY HIDTA KYG E
Sbjct: 5 PVIELNDGHRIPQIGLGTW----PLDD-----HQVAAAVVNAVEGGYRHIDTAVKYGNEK 55
Query: 309 QVGRALTKKFSEGLKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPI 488
VG + S GL R +FITTKL + +++ + L SL+ L L+YVDL LIHWP+
Sbjct: 56 GVGNGIR---SSGLDRSELFITTKLDGEFQGQDRAVAGLDGSLKRLGLDYVDLLLIHWPL 112
>UniRef50_Q890A0 Cluster: Oxidoreductase; n=6; Lactobacillales|Rep:
Oxidoreductase - Lactobacillus plantarum
Length = 282
Score = 92.7 bits (220), Expect = 1e-17
Identities = 61/149 (40%), Positives = 80/149 (53%)
Frame = +3
Query: 138 QLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQVG 317
QL++G NIP VA GTW P G+ T QAV AL AGY HIDTA Y E VG
Sbjct: 9 QLANGVNIPKVAFGTW--QIPGGEA------TYQAVRAALAAGYRHIDTALAYQNEASVG 60
Query: 318 RALTKKFSEGLKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPIAMF 497
+A+ G+ RE IF+TTKL + + +SL+NL L+YVDLYL+H P
Sbjct: 61 QAIR---DSGIPREQIFVTTKLPAETKSYQGALNDFDRSLKNLGLDYVDLYLVHAPWPWG 117
Query: 498 ENDTLLDNVDFLDTWRGMIDAKKLGLTKS 584
+ + D + LD W+ M + G K+
Sbjct: 118 QVGRVYDEAN-LDVWQAMEAIYQSGRAKA 145
>UniRef50_Q9VHX4 Cluster: CG2767-PA; n=4; Endopterygota|Rep:
CG2767-PA - Drosophila melanogaster (Fruit fly)
Length = 329
Score = 92.7 bits (220), Expect = 1e-17
Identities = 51/125 (40%), Positives = 72/125 (57%), Gaps = 1/125 (0%)
Frame = +3
Query: 135 LQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQV 314
L ++G +PV+ +GTW + E A+ ALEAGY HIDTA YG E +
Sbjct: 7 LTFNNGEKMPVIGIGTWQAS---------DEEIETAIDAALEAGYRHIDTAPVYGNEKAI 57
Query: 315 GRALTKKFSEG-LKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPIA 491
GR L + G +KRE +FI TK+ + +V P ++KSLE+L L+YVDLYL+H P
Sbjct: 58 GRVLKRWLDAGKVKREELFIVTKVPPVSNRPHEVEPTIKKSLEDLQLDYVDLYLVHTPFT 117
Query: 492 MFEND 506
+ N+
Sbjct: 118 ININE 122
>UniRef50_Q4PAT5 Cluster: Putative uncharacterized protein; n=1;
Ustilago maydis|Rep: Putative uncharacterized protein -
Ustilago maydis (Smut fungus)
Length = 700
Score = 92.7 bits (220), Expect = 1e-17
Identities = 49/121 (40%), Positives = 70/121 (57%)
Frame = +3
Query: 141 LSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQVGR 320
L++G IP + GTW K Q T AV +A++ GY HID A+ Y ED V
Sbjct: 14 LANGAQIPKLGFGTW-----KMSKEQAT----PAVAHAIKTGYRHIDCAWAYRNEDAVAA 64
Query: 321 ALTKKFSEGLKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPIAMFE 500
+ K G+ R +++T+KLWNS+H E V AL SL++L +Y+DLYL+HWP+A
Sbjct: 65 GIKKA---GVPRSQLWLTSKLWNSFHHPEHVEKALDASLKDLGTDYLDLYLMHWPVAFLN 121
Query: 501 N 503
+
Sbjct: 122 S 122
>UniRef50_Q03PG5 Cluster: Aldo/keto reductase of diketogulonate
reductase family; n=1; Lactobacillus brevis ATCC
367|Rep: Aldo/keto reductase of diketogulonate reductase
family - Lactobacillus brevis (strain ATCC 367 / JCM
1170)
Length = 268
Score = 92.3 bits (219), Expect = 2e-17
Identities = 55/138 (39%), Positives = 80/138 (57%)
Frame = +3
Query: 132 TLQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQ 311
T QLS+G IP++ GT+L + D A+ AL+AGY H+D A+ YG E
Sbjct: 3 TTQLSNGVTIPMLGFGTYLID---------SKDVPAAIKTALDAGYRHLDCAHIYGNEPA 53
Query: 312 VGRALTKKFSEGLKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPIA 491
VG A+ + G+ R +FIT+K+WN+ ++ + A ++L +L L+Y+DLYLIHWP
Sbjct: 54 VGEAIK---ASGIDRSDLFITSKVWNADQGYDKTLAAFDQTLSDLQLDYLDLYLIHWP-- 108
Query: 492 MFENDTLLDNVDFLDTWR 545
E+D L LDTWR
Sbjct: 109 -NEDDFELT----LDTWR 121
>UniRef50_Q568D7 Cluster: Zgc:110366; n=7; Euteleostomi|Rep:
Zgc:110366 - Danio rerio (Zebrafish) (Brachydanio rerio)
Length = 289
Score = 91.9 bits (218), Expect = 2e-17
Identities = 56/156 (35%), Positives = 87/156 (55%), Gaps = 1/156 (0%)
Frame = +3
Query: 120 LIVPTLQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYAL-EAGYTHIDTAYKY 296
L P + L +G NIP++ LGT H + +AV+YAL E G HIDTA +Y
Sbjct: 11 LSCPAVPLHNGLNIPILGLGT--SH--------YGGYSHEAVLYALQECGIRHIDTAKRY 60
Query: 297 GIEDQVGRALTKKFSEGLKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLI 476
G E+ +G+A+T+ G++RE +++TTKLW + + A R S L ++Y+DLYL+
Sbjct: 61 GCEEALGKAVTES---GVQREELWVTTKLWPGDYGYQSTKQACRDSRARLGVDYLDLYLM 117
Query: 477 HWPIAMFENDTLLDNVDFLDTWRGMIDAKKLGLTKS 584
HWP +M + L+TWR + + GL ++
Sbjct: 118 HWPDSMVPGRS--SQEVRLETWRALEELYDEGLCRA 151
>UniRef50_Q4JX70 Cluster: Putative oxidoreductase; n=1;
Corynebacterium jeikeium K411|Rep: Putative
oxidoreductase - Corynebacterium jeikeium (strain K411)
Length = 285
Score = 91.9 bits (218), Expect = 2e-17
Identities = 52/122 (42%), Positives = 74/122 (60%), Gaps = 2/122 (1%)
Frame = +3
Query: 126 VPTLQLSSGGNIPVVALGTWLGHRPKGKVVQVTN-DTEQAVIYALEAGYTHIDTAYKYGI 302
VPTL+++ G P + LG W Q+++ DT +V A+E GY HIDTA YG
Sbjct: 8 VPTLEMNDGKTTPQLGLGVW----------QLSDEDTYTSVRAAIETGYRHIDTAAIYGN 57
Query: 303 EDQVGRALTKKFSEG-LKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIH 479
E+ VGRA+ G ++RE +FITTKLWN+ ++ A +S + L ++YVDLYL+H
Sbjct: 58 EEAVGRAVADAVKAGDVQREELFITTKLWNA--DQACGKEAFAESQKKLGMDYVDLYLLH 115
Query: 480 WP 485
WP
Sbjct: 116 WP 117
>UniRef50_A2EHN6 Cluster: Oxidoreductase, aldo/keto reductase family
protein; n=10; Trichomonas vaginalis|Rep:
Oxidoreductase, aldo/keto reductase family protein -
Trichomonas vaginalis G3
Length = 312
Score = 91.9 bits (218), Expect = 2e-17
Identities = 57/157 (36%), Positives = 90/157 (57%), Gaps = 16/157 (10%)
Frame = +3
Query: 159 IPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALE-AGYTHIDTAYKYGIEDQVGRALTKK 335
IP + GT+L + P + A+ YA+E G HIDTA+ Y ++ +G L +
Sbjct: 3 IPQLGFGTYLANDPA--------KLKAALHYAIEECGVRHIDTAFAYYNQNVIGETLKEI 54
Query: 336 FSEG-LKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPIAM----FE 500
F++G +KRE +FITTKLW ++H ++ V P L ++L L L YVDL+LIH PIA +
Sbjct: 55 FAKGKIKREDMFITTKLWCTHHRKDLVEPELHENLAQLQLSYVDLFLIHQPIAFKSLPAK 114
Query: 501 NDTLL----------DNVDFLDTWRGMIDAKKLGLTK 581
+ T++ + +D L+T+ M + +K GLT+
Sbjct: 115 DGTMMPKDEKGKIQYEQIDILETYHAMEECQKKGLTR 151
>UniRef50_A4FEB9 Cluster: 2,5-diketo-D-gluconic acid reductase; n=1;
Saccharopolyspora erythraea NRRL 2338|Rep:
2,5-diketo-D-gluconic acid reductase - Saccharopolyspora
erythraea (strain NRRL 23338)
Length = 159
Score = 91.5 bits (217), Expect = 3e-17
Identities = 56/121 (46%), Positives = 70/121 (57%), Gaps = 1/121 (0%)
Frame = +3
Query: 126 VPTLQLSSGGNIPVVALGTWLGHRPKGKVVQVTND-TEQAVIYALEAGYTHIDTAYKYGI 302
VPT+ L++G +P + G V QV D T AV ALEAGY IDTA YG
Sbjct: 4 VPTVTLNNGVEMPQLGYG----------VFQVPEDETAAAVGAALEAGYRSIDTAAAYGN 53
Query: 303 EDQVGRALTKKFSEGLKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHW 482
E VGRAL GL R+ +F+TTKLWN+ + + A SLE L L+++DLYLIHW
Sbjct: 54 EAAVGRALA---GSGLARDELFVTTKLWNADQGYDNALRAFDTSLELLGLDHLDLYLIHW 110
Query: 483 P 485
P
Sbjct: 111 P 111
>UniRef50_Q7G765 Cluster: Probable NAD(P)H-dependent oxidoreductase
2; n=6; Magnoliophyta|Rep: Probable NAD(P)H-dependent
oxidoreductase 2 - Oryza sativa subsp. japonica (Rice)
Length = 322
Score = 91.5 bits (217), Expect = 3e-17
Identities = 47/131 (35%), Positives = 71/131 (54%), Gaps = 10/131 (7%)
Frame = +3
Query: 222 TNDTEQAVIYALEAGYTHIDTAYKYGIEDQVGRALTKKFSEGL--KRESIFITTKLWNSY 395
+ +T A++ A+E GY H DTA Y E V A+ + GL R +F+T+KLW S
Sbjct: 33 SEETTAALLRAIELGYRHFDTARLYATEGCVSEAVAEAVRRGLVASRADVFVTSKLWCSD 92
Query: 396 HEREQVIPALRKSLENLNLEYVDLYLIHWPIAM--------FENDTLLDNVDFLDTWRGM 551
+V+PA R++L NL ++YVDL L+HWP + F + + D WRGM
Sbjct: 93 LHAGRVVPAARETLRNLGMDYVDLLLVHWPATVAPGSYDFPFPKEEMAPAFDMEGVWRGM 152
Query: 552 IDAKKLGLTKS 584
+ +LGL ++
Sbjct: 153 EECHRLGLARA 163
>UniRef50_Q8ZI40 Cluster: 2,5-diketo-D-gluconic acid reductase A;
n=74; Bacteria|Rep: 2,5-diketo-D-gluconic acid reductase
A - Yersinia pestis
Length = 277
Score = 91.5 bits (217), Expect = 3e-17
Identities = 60/152 (39%), Positives = 80/152 (52%)
Frame = +3
Query: 129 PTLQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIED 308
P ++L G +P + LG W +TE AV ALE GY IDTA Y E+
Sbjct: 5 PLIKLYDGRLMPQLGLGVWQAS---------IQETELAVSKALEVGYRSIDTAAIYKNEE 55
Query: 309 QVGRALTKKFSEGLKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPI 488
VG+AL + + R+ +FITTKLWN Q AL SL+ L L+YVDLYLIHWP
Sbjct: 56 GVGKALK---AAAVARDELFITTKLWNDDQHNPQ--QALETSLQKLQLDYVDLYLIHWP- 109
Query: 489 AMFENDTLLDNVDFLDTWRGMIDAKKLGLTKS 584
D D+ ++ WR ++ K+ GL +S
Sbjct: 110 -----DPKQDH--YVSAWRELVTLKEQGLIRS 134
>UniRef50_Q5HR31 Cluster: Oxidoreductase, aldo/keto reductase
family; n=3; Staphylococcus|Rep: Oxidoreductase,
aldo/keto reductase family - Staphylococcus epidermidis
(strain ATCC 35984 / RP62A)
Length = 279
Score = 91.1 bits (216), Expect = 4e-17
Identities = 55/124 (44%), Positives = 73/124 (58%)
Frame = +3
Query: 141 LSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQVGR 320
L++G +P V LG + K+ E+ V AL+AGY DTAY YG E +G
Sbjct: 8 LNNGYPMPAVGLGVY-------KIAD--EQMEEVVRTALDAGYRAFDTAYFYGNEKALGS 58
Query: 321 ALTKKFSEGLKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPIAMFE 500
AL K S ++R+ +FIT+KLWN Y +Q I KSL+NL L+Y+DL+LIHWP E
Sbjct: 59 AL--KHSN-VERDELFITSKLWNDYQGYDQTIEYFNKSLDNLGLDYLDLFLIHWPC---E 112
Query: 501 NDTL 512
ND L
Sbjct: 113 NDQL 116
>UniRef50_Q6NII7 Cluster: Putative oxidoreductase; n=2;
Corynebacterium|Rep: Putative oxidoreductase -
Corynebacterium diphtheriae
Length = 290
Score = 90.6 bits (215), Expect = 6e-17
Identities = 46/122 (37%), Positives = 72/122 (59%), Gaps = 1/122 (0%)
Frame = +3
Query: 123 IVPTLQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGI 302
I+PT+ L+ G +P + GT+ K+ + D +AV A+E GY HIDTA Y
Sbjct: 10 IIPTITLNDGTEMPAIGFGTY-------KLRE--QDAYRAVRSAIEVGYRHIDTASLYKN 60
Query: 303 EDQVGRALTKKFSEG-LKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIH 479
E++VGRA+ + G + R+ +FITTK+WN H + + ++SL L L+Y+D ++H
Sbjct: 61 EEEVGRAVADAITAGEVARDELFITTKVWNDMHGDQLTQRSFQESLHRLGLDYIDCCMVH 120
Query: 480 WP 485
WP
Sbjct: 121 WP 122
>UniRef50_Q7XY49 Cluster: Mannose 6-phosphate reductase; n=1;
Griffithsia japonica|Rep: Mannose 6-phosphate reductase
- Griffithsia japonica (Red alga)
Length = 174
Score = 90.6 bits (215), Expect = 6e-17
Identities = 50/116 (43%), Positives = 71/116 (61%), Gaps = 1/116 (0%)
Frame = +3
Query: 132 TLQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQ 311
T L SG +P+ GTW K V +TEQAV AL AGY HID A Y E
Sbjct: 5 TATLQSGAKMPLNGFGTW-----KASV----EETEQAVTAALRAGYRHIDCAAVYWNEAA 55
Query: 312 VGRALTKKFSEGL-KRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLI 476
VG A++K S G+ KRE +FIT+K+WN+ H ++V+ + R+SL++ ++Y DL+L+
Sbjct: 56 VGTAISKAISGGVVKREDLFITSKVWNTCHATDKVVDSCRQSLKDHQVDYFDLFLV 111
>UniRef50_Q6C2L0 Cluster: Yarrowia lipolytica chromosome F of strain
CLIB122 of Yarrowia lipolytica; n=3; Yarrowia
lipolytica|Rep: Yarrowia lipolytica chromosome F of
strain CLIB122 of Yarrowia lipolytica - Yarrowia
lipolytica (Candida lipolytica)
Length = 324
Score = 90.6 bits (215), Expect = 6e-17
Identities = 50/125 (40%), Positives = 78/125 (62%), Gaps = 1/125 (0%)
Frame = +3
Query: 123 IVPTLQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGI 302
I + +L+ G +IP + LGT G V E+ V A++ GY HIDTA+ YG
Sbjct: 3 ITDSFKLNDGHSIPALGLGT----ASDGNV-------EEVVYAAIKNGYRHIDTAFIYGS 51
Query: 303 EDQVGRALTKKFSEGL-KRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIH 479
E VG+ + + E L KRE++F+TTK+W +++ R V +L SL++L+L+YVDL L+H
Sbjct: 52 EVDVGKGIKRAIDEELVKRENLFVTTKVWPTFYNR--VSESLDISLKDLSLDYVDLLLVH 109
Query: 480 WPIAM 494
WP+++
Sbjct: 110 WPVSL 114
>UniRef50_Q8J0K1 Cluster: 4-dihydromethyltrisporate dehydrogenase;
n=2; Parasitella parasitica|Rep:
4-dihydromethyltrisporate dehydrogenase - Parasitella
parasitica
Length = 321
Score = 90.2 bits (214), Expect = 7e-17
Identities = 42/90 (46%), Positives = 57/90 (63%), Gaps = 1/90 (1%)
Frame = +3
Query: 228 DTEQAVIYALEAGYTHIDTAYKYGIEDQVGRALTKKFSEGL-KRESIFITTKLWNSYHER 404
D E + A++ GY D A YG E +VGR + K EGL KRE +FI TKLWN++H +
Sbjct: 29 DAENTIYQAIKIGYRLFDGACDYGNEVEVGRGINKAIKEGLVKREELFIVTKLWNTFHSK 88
Query: 405 EQVIPALRKSLENLNLEYVDLYLIHWPIAM 494
+ V A + L++ LEY DLYLIH+PI +
Sbjct: 89 QHVRTAFDRQLKDWGLEYFDLYLIHFPIPL 118
>UniRef50_Q9FJK0 Cluster: Aldose reductase-like protein; n=3; core
eudicotyledons|Rep: Aldose reductase-like protein -
Arabidopsis thaliana (Mouse-ear cress)
Length = 316
Score = 89.8 bits (213), Expect = 1e-16
Identities = 53/158 (33%), Positives = 88/158 (55%), Gaps = 9/158 (5%)
Frame = +3
Query: 138 QLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQVG 317
+L G IP++ +GT+ + + T AV A++ GY H DTA YG E+ +G
Sbjct: 7 RLRCGETIPLLGMGTYCPQKDR-------ESTISAVHQAIKIGYRHFDTAKIYGSEEALG 59
Query: 318 RALTKKFSEG-LKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPIAM 494
AL + S G ++R+ +F+T+KLW+S H I AL ++L+ + L+Y+D YL+HWPI +
Sbjct: 60 TALGQAISYGTVQRDDLFVTSKLWSSDH--HDPISALIQTLKTMGLDYLDNYLVHWPIKL 117
Query: 495 F--------ENDTLLDNVDFLDTWRGMIDAKKLGLTKS 584
+ D ++ +TW+GM ++GL +S
Sbjct: 118 KPGVSEPIPKEDEFEKDLGIEETWQGMERCLEMGLCRS 155
>UniRef50_Q8G7K9 Cluster: Dehydrogenase or reductase protein; n=4;
Bifidobacterium|Rep: Dehydrogenase or reductase protein
- Bifidobacterium longum
Length = 289
Score = 89.4 bits (212), Expect = 1e-16
Identities = 65/186 (34%), Positives = 93/186 (50%), Gaps = 2/186 (1%)
Frame = +3
Query: 126 VPTLQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIE 305
VP + L G +IP V LG L +G V V + ALEAGY HID A Y E
Sbjct: 11 VPDIALKDGHSIPQVGLGV-LRIDDEGVVPVVES--------ALEAGYRHIDGAAGYNNE 61
Query: 306 DQVGRALTKK-FSEGLKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHW 482
VGRAL +++G KRE++++TTKL +S + + A SL+ L L+YVD+Y+IHW
Sbjct: 62 AGVGRALAASGYNKGAKRETLWVTTKLRDSQQGYDSALKAFDNSLKLLQLDYVDMYMIHW 121
Query: 483 PIAMFENDTLLDNVDFLDTWRGMIDAKKLGLTKS*ASPTLTRTNPEDHRQRTGEXSAL-Q 659
P T DTW+ + + G+ ++ + + + TG A+ Q
Sbjct: 122 PTPFDWRST--------DTWKAFVKLRDEGMARTLGVCNFMPADLKRLHEETGAWPAVNQ 173
Query: 660 IELTST 677
IEL T
Sbjct: 174 IELHPT 179
>UniRef50_Q0CLQ2 Cluster: Putative uncharacterized protein; n=1;
Aspergillus terreus NIH2624|Rep: Putative
uncharacterized protein - Aspergillus terreus (strain
NIH 2624)
Length = 301
Score = 89.4 bits (212), Expect = 1e-16
Identities = 51/127 (40%), Positives = 76/127 (59%)
Frame = +3
Query: 132 TLQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQ 311
+ +LSSG ++P V LGTWL +P ++ E AV AL GY HID A Y E++
Sbjct: 6 SFKLSSGYDMPAVGLGTWLS-KP--------HEVENAVETALRLGYRHIDAAACYLNENE 56
Query: 312 VGRALTKKFSEGLKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPIA 491
VG K G+ R+ IFIT+KLWN++H + V A+ K+L++L +Y+DLYL+ +
Sbjct: 57 VGNGWKKS---GVPRDQIFITSKLWNTHHHPDHVEEAVNKTLKDLQTDYLDLYLVFPSLL 113
Query: 492 MFENDTL 512
+ +D L
Sbjct: 114 VLIHDLL 120
>UniRef50_UPI0000E4A7CE Cluster: PREDICTED: similar to LOC553452
protein; n=6; Strongylocentrotus purpuratus|Rep:
PREDICTED: similar to LOC553452 protein -
Strongylocentrotus purpuratus
Length = 321
Score = 89.0 bits (211), Expect = 2e-16
Identities = 55/161 (34%), Positives = 85/161 (52%), Gaps = 13/161 (8%)
Frame = +3
Query: 141 LSSGGNIPVVALGTW-LGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQVG 317
L G +P++ GTW + G+V++ A++ GY HID A YG E VG
Sbjct: 10 LPGGRKLPLLGFGTWQIKPEEVGRVIET----------AIDCGYRHIDEASLYGNEKGVG 59
Query: 318 RALTKKFSEG-LKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPIA- 491
+ K +G +KRE +F+T+KLW + +V P+ R+SL +L L Y+DL+LIH P +
Sbjct: 60 DGIKAKIDDGTIKREDLFVTSKLWVTDSHPSRVEPSCRQSLSDLGLAYLDLFLIHCPTSA 119
Query: 492 --------MFENDTLL--DNVDFLDTWRGMIDAKKLGLTKS 584
M +N + D +D++DTWR M GL ++
Sbjct: 120 VGGKGPFPMDDNGLFIGDDTIDYVDTWRIMESLVDKGLVRA 160
>UniRef50_Q9U2J5 Cluster: Putative uncharacterized protein; n=2;
Caenorhabditis|Rep: Putative uncharacterized protein -
Caenorhabditis elegans
Length = 339
Score = 89.0 bits (211), Expect = 2e-16
Identities = 52/170 (30%), Positives = 86/170 (50%), Gaps = 16/170 (9%)
Frame = +3
Query: 123 IVPTLQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGI 302
I T+ L+SG +PV+ GTW PK + D ALEAGY HID+A +
Sbjct: 3 IADTVTLNSGYEMPVIGYGTW--QLPKNLAAERVRD-------ALEAGYRHIDSALSFKN 53
Query: 303 EDQVGRALTKKFS-EGLKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIH 479
+++V + ++RE +F+++K+WN+YH R + + + + LE Y+DL +IH
Sbjct: 54 QEEVAAGIKDWCKIRKVRREELFLSSKIWNTYHSRNRCMQQIDEMLEIFETTYMDLIVIH 113
Query: 480 WPIAMFEND---------------TLLDNVDFLDTWRGMIDAKKLGLTKS 584
WP E++ +VD+L+TW+ + DA + G +S
Sbjct: 114 WPFGWAEDEPPGERGLWPRGANGKMRYSDVDYLETWKALEDAHRSGKIRS 163
>UniRef50_Q4Q5N9 Cluster: Prostaglandin f synthase, putative; n=7;
cellular organisms|Rep: Prostaglandin f synthase,
putative - Leishmania major
Length = 279
Score = 88.6 bits (210), Expect = 2e-16
Identities = 47/115 (40%), Positives = 68/115 (59%)
Frame = +3
Query: 141 LSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQVGR 320
LS+G +P + +GTW + +VV + +A+ AGY H+DTA+ Y E VG+
Sbjct: 10 LSNGVQVPQLGIGTWEA-KDGNEVVNIK--------WAVNAGYRHVDTAHYYKNEKGVGQ 60
Query: 321 ALTKKFSEGLKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWP 485
+++ G+ R IF+TTKLWN H E + A +S + L +EYVDLYLIHWP
Sbjct: 61 GISEC---GVPRSDIFVTTKLWNYDHGYESALAAFEQSRQALGVEYVDLYLIHWP 112
>UniRef50_P38115 Cluster: D-arabinose dehydrogenase [NAD(P)+] heavy
chain; n=3; Saccharomycetaceae|Rep: D-arabinose
dehydrogenase [NAD(P)+] heavy chain - Saccharomyces
cerevisiae (Baker's yeast)
Length = 344
Score = 88.2 bits (209), Expect = 3e-16
Identities = 52/117 (44%), Positives = 73/117 (62%), Gaps = 1/117 (0%)
Frame = +3
Query: 141 LSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQVGR 320
L++G IP + LGT P K+ + T+QAV A++AGY HIDTA+ Y E VG
Sbjct: 27 LNNGVRIPALGLGT---ANPHEKLAE----TKQAVKAAIKAGYRHIDTAWAYETEPFVGE 79
Query: 321 ALTKKFSEG-LKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPI 488
A+ + +G +KRE +FITTK+W ++V +L +SL+ L LEYVDL L HWP+
Sbjct: 80 AIKELLEDGSIKREDLFITTKVWPVLW--DEVDRSLNESLKALGLEYVDLLLQHWPL 134
>UniRef50_Q5TNP1 Cluster: ENSANGP00000029046; n=2; Culicidae|Rep:
ENSANGP00000029046 - Anopheles gambiae str. PEST
Length = 331
Score = 87.8 bits (208), Expect = 4e-16
Identities = 53/120 (44%), Positives = 72/120 (60%), Gaps = 2/120 (1%)
Frame = +3
Query: 132 TLQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQ 311
T +L++G +IP+ GT+ H + + QV + YALEAGY HIDTA Y E+
Sbjct: 33 TFKLNTGFDIPLAGFGTYQIHGQE-LIYQVLD-------YALEAGYRHIDTAVVYRNEEY 84
Query: 312 VGRALTKKFSE-GLKRESIFITTKLWNSYHEREQVIPAL-RKSLENLNLEYVDLYLIHWP 485
+G AL + LKRE IFIT+KL + + E + + RKSL NL +Y+DLYLIHWP
Sbjct: 85 IGTALKTLLPKYNLKREDIFITSKLISQSGKDEAFVEQMVRKSLANLQTDYLDLYLIHWP 144
>UniRef50_Q7N0E4 Cluster: 2,5-diketo-D-gluconic acid reductase A;
n=2; Bacteria|Rep: 2,5-diketo-D-gluconic acid reductase
A - Photorhabdus luminescens subsp. laumondii
Length = 292
Score = 87.4 bits (207), Expect = 5e-16
Identities = 58/152 (38%), Positives = 81/152 (53%)
Frame = +3
Query: 129 PTLQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIED 308
P ++L+ G ++P + LG+W Q +T A AL+ GY IDTA Y E
Sbjct: 5 PIIRLADGNHMPQLGLGSWASDD------QQIAETIHA---ALDIGYRAIDTAAIYNNEK 55
Query: 309 QVGRALTKKFSEGLKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPI 488
VG AL + + RE IF+TTKLWN H + AL +SLE L L+YVDLYLIHWP
Sbjct: 56 GVGNALQET---DIPREDIFVTTKLWNDRHLDARA--ALTESLEKLQLDYVDLYLIHWPA 110
Query: 489 AMFENDTLLDNVDFLDTWRGMIDAKKLGLTKS 584
+ ++ W+ +I+ +K GL +S
Sbjct: 111 PPQD--------QYVGAWQQLIELQKEGLIRS 134
>UniRef50_A6ESC0 Cluster: ARA1; n=1; unidentified eubacterium
SCB49|Rep: ARA1 - unidentified eubacterium SCB49
Length = 280
Score = 87.4 bits (207), Expect = 5e-16
Identities = 54/151 (35%), Positives = 78/151 (51%), Gaps = 2/151 (1%)
Frame = +3
Query: 138 QLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQVG 317
+L++ NIP + GTW P G+ A+ A++AGY HID A Y E VG
Sbjct: 6 KLNNNINIPAIGFGTW--QTPDGQTAI------NAIKTAIDAGYKHIDAAAIYKNEKGVG 57
Query: 318 RALTKKFSEGLKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPIA-- 491
+ + + R+ +F+T+K+WN E + A ++ +L L+Y+DLYLIHWP A
Sbjct: 58 LGIKEA---NIDRKDLFVTSKVWNEQRGYENTLKAFDNTINDLQLDYLDLYLIHWPAAAH 114
Query: 492 MFENDTLLDNVDFLDTWRGMIDAKKLGLTKS 584
FEN L+N DTW M K G K+
Sbjct: 115 QFENWKQLNN----DTWSAMEKLYKDGKIKA 141
>UniRef50_Q9X0A2 Cluster: Oxidoreductase, aldo/keto reductase
family; n=21; Bacteria|Rep: Oxidoreductase, aldo/keto
reductase family - Thermotoga maritima
Length = 286
Score = 87.0 bits (206), Expect = 7e-16
Identities = 51/121 (42%), Positives = 70/121 (57%), Gaps = 1/121 (0%)
Frame = +3
Query: 126 VPTLQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIE 305
VP + L++G +P++ G + P K TE+ V A++ GY IDTA Y E
Sbjct: 3 VPKVTLNNGVEMPILGYGVF--QIPPEK-------TEECVYEAIKVGYRLIDTAASYMNE 53
Query: 306 DQVGRALTKKFSEGL-KRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHW 482
+ VGRA+ + EG+ +RE +F+TTKLW S E A KSL+ L LEY+DLYLIH
Sbjct: 54 EGVGRAIKRAIDEGIVRREELFVTTKLWVSDVGYESTKKAFEKSLKKLQLEYIDLYLIHQ 113
Query: 483 P 485
P
Sbjct: 114 P 114
>UniRef50_Q1VRG6 Cluster: YvgN; n=1; Psychroflexus torquis ATCC
700755|Rep: YvgN - Psychroflexus torquis ATCC 700755
Length = 280
Score = 87.0 bits (206), Expect = 7e-16
Identities = 59/150 (39%), Positives = 79/150 (52%), Gaps = 2/150 (1%)
Frame = +3
Query: 141 LSSGGNIPVVALGTWLGHRPKG-KVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQVG 317
L+ G IP+V GT+ + +G K +Q + AL GY IDT Y E+ VG
Sbjct: 5 LNDGNRIPIVGFGTYKANEEEGIKSIQKS---------ALTLGYRLIDTVAIYQNEEAVG 55
Query: 318 RALTKKFSEGLKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPI-AM 494
+A+ + G+ RE IF+TTKLW +Q AL +SL L+L Y+DLYLIHWP A+
Sbjct: 56 KAIKAR---GVLREEIFVTTKLWRENLGYKQTRIALDESLRKLDLNYIDLYLIHWPANAI 112
Query: 495 FENDTLLDNVDFLDTWRGMIDAKKLGLTKS 584
D N DTWR M + + G KS
Sbjct: 113 NYKDWQKTNA---DTWRAMEELQAEGKIKS 139
>UniRef50_Q1IN88 Cluster: Aldehyde reductase; n=5; Bacteria|Rep:
Aldehyde reductase - Acidobacteria bacterium (strain
Ellin345)
Length = 313
Score = 87.0 bits (206), Expect = 7e-16
Identities = 50/119 (42%), Positives = 65/119 (54%), Gaps = 1/119 (0%)
Frame = +3
Query: 153 GNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQVGRALTK 332
G+IP + GT + + T D AL AG+ H D A +Y E +VG AL
Sbjct: 18 GHIPALGFGTLIAD--PALTITATRD-------ALAAGFRHFDCAERYRNEREVGEALRA 68
Query: 333 KFSEG-LKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPIAMFEND 506
+ G + RE IF+TTKLWN+ H E+V PA SL+ L L+Y+DLYLIH P A D
Sbjct: 69 GRAAGNIAREEIFVTTKLWNTNHRPERVEPAFEASLDRLGLDYLDLYLIHTPFAFQPGD 127
>UniRef50_A6W8E7 Cluster: 2,5-didehydrogluconate reductase; n=3;
Actinomycetales|Rep: 2,5-didehydrogluconate reductase -
Kineococcus radiotolerans SRS30216
Length = 289
Score = 87.0 bits (206), Expect = 7e-16
Identities = 58/156 (37%), Positives = 84/156 (53%), Gaps = 1/156 (0%)
Frame = +3
Query: 120 LIVPTLQLSSGGNIPVVALGTWLGHRPKGKVVQVT-NDTEQAVIYALEAGYTHIDTAYKY 296
+ VPT+ L+ G IP + G V Q+ DT QAV AL+ GY HIDTA Y
Sbjct: 10 MTVPTILLNDGREIPQLGFG----------VFQIEPGDTAQAVKTALDLGYRHIDTAQMY 59
Query: 297 GIEDQVGRALTKKFSEGLKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLI 476
G E +V + + G+ R+ I++T+KL N +HE + A+ S+E L +DLYLI
Sbjct: 60 GNEAEVAQGIA---DSGVPRDEIWVTSKLNNGFHEPDAARKAVDDSVEKLR-GPIDLYLI 115
Query: 477 HWPIAMFENDTLLDNVDFLDTWRGMIDAKKLGLTKS 584
HWP+ TL DF+ TW+ + +A+ G +S
Sbjct: 116 HWPL-----PTLYGG-DFVSTWKVLEEARAAGKLRS 145
>UniRef50_A7PNI3 Cluster: Chromosome chr1 scaffold_22, whole genome
shotgun sequence; n=2; Vitis vinifera|Rep: Chromosome
chr1 scaffold_22, whole genome shotgun sequence - Vitis
vinifera (Grape)
Length = 360
Score = 87.0 bits (206), Expect = 7e-16
Identities = 47/115 (40%), Positives = 70/115 (60%)
Frame = +3
Query: 141 LSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQVGR 320
L++ IP + LGTW G + V +AV AL GY ID A+ YG E +VG
Sbjct: 14 LNTKAKIPAIGLGTW----QSGGDLCV-----EAVKRALSEGYRQIDCAHLYGNEVEVGE 64
Query: 321 ALTKKFSEGLKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWP 485
AL + F+ LKRE +F+T+KL+ + + ++ ++R SL+NL + Y+DLYL+HWP
Sbjct: 65 ALAEAFNGSLKREDVFLTSKLYCTMNSLNKIENSVRVSLKNLGVTYLDLYLMHWP 119
>UniRef50_Q22352 Cluster: Putative uncharacterized protein T08H10.1;
n=2; Caenorhabditis|Rep: Putative uncharacterized
protein T08H10.1 - Caenorhabditis elegans
Length = 333
Score = 87.0 bits (206), Expect = 7e-16
Identities = 61/169 (36%), Positives = 87/169 (51%), Gaps = 14/169 (8%)
Frame = +3
Query: 120 LIVPTLQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIY--ALEAGYTHIDTAYK 293
+ V ++ L++G +P+ LGTW QV ++ E V AL+AGY IDTA+
Sbjct: 1 MTVDSIPLNTGAQLPLFGLGTW----------QVKDEAELTVALRAALDAGYRLIDTAHL 50
Query: 294 YGIEDQVGRALTKKFSEG-LKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLY 470
Y E +G+ L + S G LKRE IF+T+KL + H E V + L+ L LEY+DLY
Sbjct: 51 YQNEHIIGKVLHEYISSGKLKREDIFVTSKLPFTAHAPEDVPKCVESQLKALQLEYIDLY 110
Query: 471 LIHWPI----------AMFENDTL-LDNVDFLDTWRGMIDAKKLGLTKS 584
LIH P + EN L + + +DTWR + K G K+
Sbjct: 111 LIHCPFPFKHQEGSFAPLMENGELAVTEIAHIDTWRALEKLYKEGKLKA 159
>UniRef50_Q03XK0 Cluster: Aldo/keto reductase of diketogulonate
reductase family; n=3; Lactobacillales|Rep: Aldo/keto
reductase of diketogulonate reductase family -
Leuconostoc mesenteroides subsp. mesenteroides (strain
ATCC 8293 /NCDO 523)
Length = 292
Score = 86.6 bits (205), Expect = 9e-16
Identities = 46/116 (39%), Positives = 71/116 (61%), Gaps = 1/116 (0%)
Frame = +3
Query: 141 LSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQVGR 320
L+SG +P++ G + VQ +QAV+ A++ GY IDTA YG E +VG
Sbjct: 6 LASGIEMPLLGFGVFQ--------VQEKGAAKQAVLDAIKTGYRLIDTAASYGNEREVGE 57
Query: 321 ALTKKFSEGL-KRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWP 485
A+ + ++G+ KRE +F+T+K+W +Q A++ SL+ LNL+Y+DLYLIH P
Sbjct: 58 AILEAINQGIVKREELFVTSKMWVQDVSAQQATAAIQSSLQRLNLDYLDLYLIHQP 113
>UniRef50_A5PDA8 Cluster: Putative oxidoreductase protein; n=1;
Erythrobacter sp. SD-21|Rep: Putative oxidoreductase
protein - Erythrobacter sp. SD-21
Length = 272
Score = 86.6 bits (205), Expect = 9e-16
Identities = 64/181 (35%), Positives = 87/181 (48%), Gaps = 1/181 (0%)
Frame = +3
Query: 129 PTLQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIED 308
PTL L+ G IP + GTW D QAV A++ GY IDTA YG E
Sbjct: 5 PTLNLNDGRQIPQLGFGTWQMEE---------EDAPQAVSTAIDVGYWLIDTAAIYGNEK 55
Query: 309 QVGRALTKKFSEGLKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPI 488
VG+ + + +S+ IF+ TK+WN ++ + A K LE L E+VD+ LIHWP
Sbjct: 56 GVGKGVGE-WSD------IFLQTKIWNDSQGYDRTLRAAEKCLERLGREHVDMLLIHWPC 108
Query: 489 AMFENDTLLDNVDFLDTWRGMIDAKKLGLTKS*ASPTLTRTNPEDHRQRTGEXSAL-QIE 665
E D F+DTW+ +I+ + G KS + + TG AL QIE
Sbjct: 109 P--EKD------QFVDTWKALIELRDAGKAKSIGVSNFREEDLKRIIDETGVTPALNQIE 160
Query: 666 L 668
L
Sbjct: 161 L 161
>UniRef50_Q7R2T6 Cluster: GLP_291_56367_57278; n=1; Giardia lamblia
ATCC 50803|Rep: GLP_291_56367_57278 - Giardia lamblia
ATCC 50803
Length = 303
Score = 86.6 bits (205), Expect = 9e-16
Identities = 36/89 (40%), Positives = 62/89 (69%), Gaps = 3/89 (3%)
Frame = +3
Query: 237 QAVIYALEAGYTHIDTAYKYGIEDQVGRALTKKFSE---GLKRESIFITTKLWNSYHERE 407
+A+ A++ GY H D AY+YG E +G + F++ G+KRE ++I +KLW ++HE E
Sbjct: 19 EAIRSAVKLGYRHFDCAYRYGNERMIGEVFKEIFNDDSYGVKREDLWIVSKLWPNFHEPE 78
Query: 408 QVIPALRKSLENLNLEYVDLYLIHWPIAM 494
+V + ++L +L LEY+D++L+HWP+A+
Sbjct: 79 KVAYQISETLRDLQLEYLDVFLMHWPLAI 107
>UniRef50_Q24C22 Cluster: Oxidoreductase, aldo/keto reductase family
protein; n=4; Oligohymenophorea|Rep: Oxidoreductase,
aldo/keto reductase family protein - Tetrahymena
thermophila SB210
Length = 297
Score = 86.2 bits (204), Expect = 1e-15
Identities = 53/153 (34%), Positives = 82/153 (53%), Gaps = 1/153 (0%)
Frame = +3
Query: 126 VPTLQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIE 305
VP L GG+IP + GT+ ++ Q ND V AL+ GYTHIDTA Y E
Sbjct: 13 VPILNFREGGSIPQIGYGTY-------ELRQ--NDCIIGVTEALKIGYTHIDTASVYRNE 63
Query: 306 DQVGRALTKKFSEGLKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWP 485
+ + + + G+KRE +FIT+K+ EQ A++ L LN++Y+D LIHWP
Sbjct: 64 QDIAKVIHNP-AYGIKREDLFITSKISPGEQGYEQAKKAVQDMLTRLNIKYLDCVLIHWP 122
Query: 486 -IAMFENDTLLDNVDFLDTWRGMIDAKKLGLTK 581
++ + + L+TW+ +I+ +K G+ K
Sbjct: 123 GVSKLPPNDPKNAQIRLETWKALIELRKAGVIK 155
>UniRef50_Q4PDR0 Cluster: Putative uncharacterized protein; n=1;
Ustilago maydis|Rep: Putative uncharacterized protein -
Ustilago maydis (Smut fungus)
Length = 339
Score = 86.2 bits (204), Expect = 1e-15
Identities = 45/128 (35%), Positives = 73/128 (57%), Gaps = 1/128 (0%)
Frame = +3
Query: 126 VPTLQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIE 305
+P+ L++G +P V +G W G G+ N+ A++ A++ GY H+DTA Y E
Sbjct: 5 IPSFTLNTGAKLPSVGMGCWQGQPGPGR----DNELVDALVRAIKVGYRHLDTATGYRNE 60
Query: 306 DQVGRALTKKFSEGLKRESIFITTKLW-NSYHEREQVIPALRKSLENLNLEYVDLYLIHW 482
+VG+A+ + G+ R IF+TTKL H+ V+ L SL L ++Y+DL+L+HW
Sbjct: 61 AEVGQAVRQS---GVARSEIFVTTKLRPGGVHD---VVQELENSLNELGIDYIDLWLLHW 114
Query: 483 PIAMFEND 506
P ++D
Sbjct: 115 PQGFTKDD 122
>UniRef50_P15339 Cluster: 2,5-diketo-D-gluconic acid reductase B;
n=6; Actinomycetales|Rep: 2,5-diketo-D-gluconic acid
reductase B - Corynebacterium sp. (strain SHS752001)
Length = 277
Score = 86.2 bits (204), Expect = 1e-15
Identities = 58/182 (31%), Positives = 94/182 (51%), Gaps = 1/182 (0%)
Frame = +3
Query: 126 VPTLQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIE 305
+PT+ L+ G LGT+ +G A++ A+++GY +DTA Y E
Sbjct: 4 IPTISLNDGRPFAEPGLGTYNLRGDEGVA---------AMVAAIDSGYRLLDTAVNYENE 54
Query: 306 DQVGRALTKKFSEGLKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWP 485
+VGRA+ + + R+ + + +K+ H R + + ++R SL+ L L+ +DL LIHWP
Sbjct: 55 SEVGRAVR---ASSVDRDELIVASKIPGRQHGRAEAVDSIRGSLDRLGLDVIDLQLIHWP 111
Query: 486 IAMFENDTLLDNVDFLDTWRGMIDAKKLGLTKS*ASPTLTRTNPEDHRQRTGEXSAL-QI 662
N ++ +LDTWRGMIDA++ GL +S T + TG A+ Q+
Sbjct: 112 -----NPSV---GRWLDTWRGMIDAREAGLVRSIGVSNFTEPMLKTLIDETGVTPAVNQV 163
Query: 663 EL 668
EL
Sbjct: 164 EL 165
>UniRef50_Q41E86 Cluster: 2,5-didehydrogluconate reductase; n=2;
Bacteria|Rep: 2,5-didehydrogluconate reductase -
Exiguobacterium sibiricum 255-15
Length = 274
Score = 85.8 bits (203), Expect = 2e-15
Identities = 49/116 (42%), Positives = 64/116 (55%)
Frame = +3
Query: 237 QAVIYALEAGYTHIDTAYKYGIEDQVGRALTKKFSEGLKRESIFITTKLWNSYHEREQVI 416
+AV AL GY IDTA Y E VGRAL G+ RE IF+TTK+WN E+ +
Sbjct: 29 EAVREALRVGYRSIDTAMIYENEAGVGRALK---DSGIPREDIFLTTKVWNKDQGYERTL 85
Query: 417 PALRKSLENLNLEYVDLYLIHWPIAMFENDTLLDNVDFLDTWRGMIDAKKLGLTKS 584
A SL+ L ++YVDLYLIHWP+ D ++DTWR + + G K+
Sbjct: 86 AAFETSLQKLGVDYVDLYLIHWPMP--------DEDLYMDTWRALEQLYRDGKAKA 133
>UniRef50_Q4P4P1 Cluster: Putative uncharacterized protein; n=1;
Ustilago maydis|Rep: Putative uncharacterized protein -
Ustilago maydis (Smut fungus)
Length = 322
Score = 85.8 bits (203), Expect = 2e-15
Identities = 52/131 (39%), Positives = 78/131 (59%), Gaps = 3/131 (2%)
Frame = +3
Query: 111 SADLIVPTLQLSSGGNIPVVALGTWLGHRPKGKVVQVTND--TEQAVIYALEAGYTHIDT 284
S ++ ++L++G IP VALG V + ND TE A +A +AGY HID+
Sbjct: 11 SGNISTQRIKLNNGQEIPQVALG----------VYKAPNDGSTENACKWAFDAGYRHIDS 60
Query: 285 AYKYGIEDQVGRALTKKFSE-GLKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYV 461
A +Y E+ VGRAL + E + R IFIT+KLW++ H++ A+ SL+ LN++Y+
Sbjct: 61 AARYMNEESVGRALAEWTKENNVPRSEIFITSKLWDADHDK--AAAAIEDSLKKLNVDYM 118
Query: 462 DLYLIHWPIAM 494
D+YL+H P M
Sbjct: 119 DMYLMHSPGTM 129
>UniRef50_P38715 Cluster: NADPH-dependent aldose reductase GRE3;
n=39; cellular organisms|Rep: NADPH-dependent aldose
reductase GRE3 - Saccharomyces cerevisiae (Baker's
yeast)
Length = 327
Score = 85.8 bits (203), Expect = 2e-15
Identities = 47/118 (39%), Positives = 70/118 (59%), Gaps = 1/118 (0%)
Frame = +3
Query: 141 LSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQVGR 320
L++G +P+V LG W + KV + A++ GY D A YG E +VG
Sbjct: 7 LNNGLKMPLVGLGCW---KIDKKVCA------NQIYEAIKLGYRLFDGACDYGNEKEVGE 57
Query: 321 ALTKKFSEGL-KRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPIA 491
+ K SEGL R+ IF+ +KLWN++H + V AL+K+L ++ L+Y+DLY IH+PIA
Sbjct: 58 GIRKAISEGLVSRKDIFVVSKLWNNFHHPDHVKLALKKTLSDMGLDYLDLYYIHFPIA 115
>UniRef50_UPI0000519CC2 Cluster: PREDICTED: similar to CG2767-PA;
n=1; Apis mellifera|Rep: PREDICTED: similar to CG2767-PA
- Apis mellifera
Length = 321
Score = 85.4 bits (202), Expect = 2e-15
Identities = 54/133 (40%), Positives = 70/133 (52%), Gaps = 1/133 (0%)
Frame = +3
Query: 132 TLQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQ 311
T+ L +G +P++ GTW + E A+ ALEAGY HIDTA Y E
Sbjct: 5 TILLPNGELMPIIGFGTWQAQE---------KELEDALNIALEAGYRHIDTATSYENEKV 55
Query: 312 VGRALTKKF-SEGLKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPI 488
+G L F S+ LKR IFI TKL + E V ++ SL+NL LEY+DLYLIH PI
Sbjct: 56 IGDVLKNWFDSKKLKRSDIFIVTKLPAVGNRAEDVEKWIKTSLQNLRLEYLDLYLIHVPI 115
Query: 489 AMFENDTLLDNVD 527
+ +L D
Sbjct: 116 GFEKVGDILHPFD 128
>UniRef50_P47137 Cluster: Probable oxidoreductase YJR096W; n=8;
Saccharomycetales|Rep: Probable oxidoreductase YJR096W -
Saccharomyces cerevisiae (Baker's yeast)
Length = 282
Score = 85.4 bits (202), Expect = 2e-15
Identities = 59/153 (38%), Positives = 84/153 (54%), Gaps = 4/153 (2%)
Frame = +3
Query: 138 QLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQVG 317
+LS+G IP +ALGT+ P+ + ++ V ++ GY H DTA YG E +VG
Sbjct: 7 KLSNGFKIPSIALGTY--DIPRSQTAEI-------VYEGVKCGYRHFDTAVLYGNEKEVG 57
Query: 318 RALTKKFSE---GLKRESIFITTKLWNSYHEREQVIPALRKSLENLN-LEYVDLYLIHWP 485
+ K +E KRE IF TTKLWNS + ++ A+R+ L ++ L+Y+DL LIH P
Sbjct: 58 DGIIKWLNEDPGNHKREEIFYTTKLWNSQNGYKRAKAAIRQCLNEVSGLQYIDLLLIHSP 117
Query: 486 IAMFENDTLLDNVDFLDTWRGMIDAKKLGLTKS 584
+ E L L+TWR M +A GL KS
Sbjct: 118 L---EGSKLR-----LETWRAMQEAVDEGLVKS 142
>UniRef50_UPI0000D9A956 Cluster: PREDICTED: similar to aldo-keto
reductase family 1, member B10, partial; n=1; Macaca
mulatta|Rep: PREDICTED: similar to aldo-keto reductase
family 1, member B10, partial - Macaca mulatta
Length = 275
Score = 85.0 bits (201), Expect = 3e-15
Identities = 44/102 (43%), Positives = 63/102 (61%), Gaps = 7/102 (6%)
Frame = +3
Query: 234 EQAVIYALEAGYTHIDTAYKYGIEDQVGRALTKKFSE-GLKRESIFITTK------LWNS 392
++AV A++AGY HID AY Y E +VG A+ +K E +KRE +FI +K LW +
Sbjct: 49 KEAVKVAIDAGYRHIDCAYVYQNEHEVGEAIQEKIQEQAVKREDLFIVSKVHMAHWLWTT 108
Query: 393 YHEREQVIPALRKSLENLNLEYVDLYLIHWPIAMFENDTLLD 518
+ ER V A K+L++L L Y+D+YLIHWP + L+D
Sbjct: 109 FFERPLVRKAFEKTLKDLKLSYLDVYLIHWPQGFKAMEELVD 150
>UniRef50_UPI00015B4912 Cluster: PREDICTED: similar to aldo-keto
reductase; n=1; Nasonia vitripennis|Rep: PREDICTED:
similar to aldo-keto reductase - Nasonia vitripennis
Length = 353
Score = 84.2 bits (199), Expect = 5e-15
Identities = 63/162 (38%), Positives = 85/162 (52%), Gaps = 13/162 (8%)
Frame = +3
Query: 138 QLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQVG 317
+LSSG N P+V LGT H V+ E + ALE G HIDT++ Y E+ +G
Sbjct: 32 RLSSGHNFPIVGLGT---HGLNEDVL------ETVLTGALEKGIGHIDTSFVYKNEETIG 82
Query: 318 RALTKKFSEGLKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPIAM- 494
+ L F++G KRE IF+T+KL + E V ++ SLE L L+Y+D+YLIH P A+
Sbjct: 83 KVLKDWFAKGGKREDIFVTSKLPYYDNHPESVEKYIKLSLEKLGLQYLDMYLIHAPFAVH 142
Query: 495 -----FENDTLLDNVDFLDT-------WRGMIDAKKLGLTKS 584
+E T D LDT W+ M K G TKS
Sbjct: 143 HKEDSYELATNEDGSVVLDTQTDPIAVWKEMEKQVKEGRTKS 184
>UniRef50_Q88TV9 Cluster: Oxidoreductase; n=4; Lactobacillus|Rep:
Oxidoreductase - Lactobacillus plantarum
Length = 288
Score = 83.8 bits (198), Expect = 6e-15
Identities = 59/163 (36%), Positives = 82/163 (50%), Gaps = 2/163 (1%)
Frame = +3
Query: 129 PTLQLSSGGNIPVVALGTWLGHRPKGKVVQVTND--TEQAVIYALEAGYTHIDTAYKYGI 302
PT+ L+ G IP + GT+ Q+ +D T QAV AL GY HIDTA Y
Sbjct: 5 PTITLNDGRAIPAIGFGTF----------QIPDDGSTYQAVKEALVIGYRHIDTAVAYFN 54
Query: 303 EDQVGRALTKKFSEGLKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHW 482
ED+VG+A+ G+ R+ I++T+KLW + + A+ +SL L L+Y+DLYLIH
Sbjct: 55 EDEVGQAIK---DSGIPRDQIWVTSKLWLQDYGFDAASRAIDRSLTKLRLDYIDLYLIHQ 111
Query: 483 PIAMFENDTLLDNVDFLDTWRGMIDAKKLGLTKS*ASPTLTRT 611
P D W+ M A+K G KS +T T
Sbjct: 112 PYG-----------DVPGAWQAMEAAQKAGKLKSIGVSNMTPT 143
>UniRef50_Q28P63 Cluster: Aldo/keto reductase; n=4;
Rhodobacteraceae|Rep: Aldo/keto reductase - Jannaschia
sp. (strain CCS1)
Length = 276
Score = 83.8 bits (198), Expect = 6e-15
Identities = 60/192 (31%), Positives = 89/192 (46%), Gaps = 2/192 (1%)
Frame = +3
Query: 129 PTLQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTE-QAVIYALEAGYTHIDTAYKYGIE 305
P ++ G IP V G W QV D + V A+E GY ID AY Y E
Sbjct: 5 PVIKFHDGAQIPQVGFGIW----------QVPQDIAGETVRSAIEIGYRMIDGAYLYMNE 54
Query: 306 DQVGRALTKKFSEGLKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWP 485
+G L + GL R+ +F+TTK+WN+ + ++ +SL+ + +E +DL LIHWP
Sbjct: 55 AGLGEGLR---ASGLPRDEVFVTTKVWNNEQGAAKARASVERSLKTIGVEQLDLVLIHWP 111
Query: 486 IAMFENDTLLDNVDFLDTWRGMIDAKKLGLTKS*ASPTLTRTNPEDHRQRTGEXSAL-QI 662
+ D +L+TW+ D + GL +S + + E TGE L QI
Sbjct: 112 VP--SQDL------YLETWKAFQDMRDEGLMRSIGTSNFNADHLERIIAETGEAPVLNQI 163
Query: 663 ELTSTAHKFHLR 698
EL + +R
Sbjct: 164 ELNPMLQQPEMR 175
>UniRef50_Q5BLA6 Cluster: Zgc:110782; n=2; Danio rerio|Rep:
Zgc:110782 - Danio rerio (Zebrafish) (Brachydanio rerio)
Length = 287
Score = 83.4 bits (197), Expect = 8e-15
Identities = 52/123 (42%), Positives = 72/123 (58%), Gaps = 1/123 (0%)
Frame = +3
Query: 120 LIVPTLQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYG 299
+IVP+++L SG +P++ LGT+ +Q +Q+V AL+AGY DTA YG
Sbjct: 1 MIVPSVRLMSGTQMPLLGLGTYK--------LQDHEQLKQSVSCALQAGYRAFDTAAVYG 52
Query: 300 IEDQVGRALTKKFSE-GLKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLI 476
E +G+ L + + GL RE +FI +KL S H LR SLE L+ EY+DLYLI
Sbjct: 53 NEAHLGQVLKELLPKYGLIREDVFIISKLAPSDHGLRAKEGCLR-SLEQLDCEYIDLYLI 111
Query: 477 HWP 485
HWP
Sbjct: 112 HWP 114
>UniRef50_Q1Q8W8 Cluster: Aldo/keto reductase; n=1; Psychrobacter
cryohalolentis K5|Rep: Aldo/keto reductase -
Psychrobacter cryohalolentis (strain K5)
Length = 282
Score = 83.4 bits (197), Expect = 8e-15
Identities = 53/152 (34%), Positives = 83/152 (54%), Gaps = 2/152 (1%)
Frame = +3
Query: 135 LQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQV 314
++ + NIPV+ LGTW + G+ D V L GY HIDTA YG E +V
Sbjct: 8 IRTAGQANIPVLGLGTW---QSTGQ------DCIDVVSQGLRMGYEHIDTAQAYGNEVEV 58
Query: 315 GRALTKKFSEGLKRESIFITTKLW--NSYHEREQVIPALRKSLENLNLEYVDLYLIHWPI 488
G+ + + G+ R+ F+TTK++ + E E+++ A ++SLENL+ +YVDL L+HWP
Sbjct: 59 GKGIKQS---GVARDKFFLTTKIFPDDMKFEPEKLVAAAKRSLENLDTDYVDLLLLHWPD 115
Query: 489 AMFENDTLLDNVDFLDTWRGMIDAKKLGLTKS 584
D V +T + + +K GLT++
Sbjct: 116 ---------DRVPLSETIPALCELQKQGLTRN 138
>UniRef50_P70883 Cluster: AkrI; n=1; Butyrivibrio fibrisolvens|Rep:
AkrI - Butyrivibrio fibrisolvens
Length = 172
Score = 83.4 bits (197), Expect = 8e-15
Identities = 49/151 (32%), Positives = 80/151 (52%), Gaps = 1/151 (0%)
Frame = +3
Query: 135 LQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQV 314
++L++G IP+ GT+ ++ N+ +V AL+ GY HIDTA Y E V
Sbjct: 8 IKLNNGTAIPMFGYGTYK--------IKDQNEAYNSVRLALKNGYRHIDTAAFYENEKFV 59
Query: 315 GRALTKKFSEG-LKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPIA 491
A+ E KRE IF+T+K W + ++ + A K++ + ++Y+DLYL+HWP A
Sbjct: 60 ANAIKDFMEESQTKREDIFVTSKAWKTELGYDKTLAAFEKTMNEMQMDYLDLYLVHWP-A 118
Query: 492 MFENDTLLDNVDFLDTWRGMIDAKKLGLTKS 584
+ D +N + TW+ M + K G K+
Sbjct: 119 SYAFDDDWENTN-RQTWKAMTEIYKSGRVKA 148
>UniRef50_Q4FY75 Cluster: Aldo-keto reductase-like protein; n=5;
Trypanosomatidae|Rep: Aldo-keto reductase-like protein -
Leishmania major strain Friedlin
Length = 372
Score = 83.0 bits (196), Expect = 1e-14
Identities = 39/91 (42%), Positives = 55/91 (60%), Gaps = 1/91 (1%)
Frame = +3
Query: 225 NDTEQAVIYALEAGYTHIDTAYKYGIEDQVGRALTKKF-SEGLKRESIFITTKLWNSYHE 401
++ AV +AL GY H+D A YG E VG AL + + +RE +F+T+KLW +
Sbjct: 43 SEATDAVAFALSCGYRHVDCAKAYGNEAAVGEALAQALRTRCTRREDLFVTSKLWPTDQH 102
Query: 402 REQVIPALRKSLENLNLEYVDLYLIHWPIAM 494
+ V A R +L L L+Y+DLYLIHWP+ M
Sbjct: 103 PDHVEAACRATLAALQLDYLDLYLIHWPVCM 133
>UniRef50_UPI0000DB6EE9 Cluster: PREDICTED: similar to C35D10.6;
n=2; Endopterygota|Rep: PREDICTED: similar to C35D10.6 -
Apis mellifera
Length = 292
Score = 82.6 bits (195), Expect = 1e-14
Identities = 56/157 (35%), Positives = 82/157 (52%), Gaps = 3/157 (1%)
Frame = +3
Query: 123 IVPTLQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGI 302
IV + LSSG ++P++ GT+ +Q Q V +L G+ IDTA Y
Sbjct: 4 IVRNVCLSSGYDMPLIGFGTYK--------IQGRELVYQVVDESLNVGFRSIDTAVGYRN 55
Query: 303 EDQVGRALTKKFSE-GLKRESIFITTKLWNSYH-EREQVIPALRKSLENLNLEYVDLYLI 476
E+ +G AL + L+R IFITTKL S + + + + ++KSL+ N Y+DLYLI
Sbjct: 56 EEDIGYALKNLLPKYNLQRSDIFITTKLPPSVNGDPKGIEQCVQKSLKAFNTTYIDLYLI 115
Query: 477 HWPIAMFENDTLLDNVDF-LDTWRGMIDAKKLGLTKS 584
HWP A +T +N TW ++D KK G +S
Sbjct: 116 HWPGATRIPETSTNNPSLRAKTWNKLVDLKKQGFIRS 152
>UniRef50_A6WDZ5 Cluster: Aldo/keto reductase; n=5; Bacteria|Rep:
Aldo/keto reductase - Kineococcus radiotolerans SRS30216
Length = 343
Score = 81.8 bits (193), Expect = 3e-14
Identities = 40/121 (33%), Positives = 64/121 (52%)
Frame = +3
Query: 123 IVPTLQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGI 302
+VP +L G +P + +GT+ R V AV A+ AGY +D A YG
Sbjct: 12 LVPRRELRGGATVPAIGIGTFGSDRYSPAEVAA------AVAGAVAAGYRLVDCAAVYGN 65
Query: 303 EDQVGRALTKKFSEGLKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHW 482
E QVG AL + G+ R+ +F+ +K+WN H + ++ +SL +L L+++D +HW
Sbjct: 66 EAQVGEALAGAVAGGVDRDELFVVSKVWNDAHAPADAVASVHRSLRDLRLDHLDAVFVHW 125
Query: 483 P 485
P
Sbjct: 126 P 126
>UniRef50_Q9P6D3 Cluster: Related to aldo-keto reductase YPR1; n=10;
Pezizomycotina|Rep: Related to aldo-keto reductase YPR1
- Neurospora crassa
Length = 322
Score = 81.8 bits (193), Expect = 3e-14
Identities = 54/155 (34%), Positives = 78/155 (50%), Gaps = 1/155 (0%)
Frame = +3
Query: 123 IVPTLQLSSGGNIPVVALGTWLGHRPKGKVVQ-VTNDTEQAVIYALEAGYTHIDTAYKYG 299
++P+L+LS G IP++ G + G ++ A + AL AGY H+D A YG
Sbjct: 23 LIPSLKLSDGNEIPMLGYGLGTANYKSGDSADTISEPIVNATLTALNAGYAHLDGAEVYG 82
Query: 300 IEDQVGRALTKKFSEGLKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIH 479
E ++GRA+ + L R S++ITTK + V + +SLE L L+YVDLYL+H
Sbjct: 83 NEVELGRAIAQ---SKLPRSSLYITTK--TIVRAGDTVTQSFNRSLEKLGLDYVDLYLLH 137
Query: 480 WPIAMFENDTLLDNVDFLDTWRGMIDAKKLGLTKS 584
P +N L WR M K G+ KS
Sbjct: 138 SPF-FAKNPEQLQ-----AAWREMEKIKDSGMAKS 166
>UniRef50_UPI00006CCCD7 Cluster: oxidoreductase, aldo/keto reductase
family protein; n=1; Tetrahymena thermophila SB210|Rep:
oxidoreductase, aldo/keto reductase family protein -
Tetrahymena thermophila SB210
Length = 323
Score = 81.4 bits (192), Expect = 3e-14
Identities = 49/156 (31%), Positives = 88/156 (56%), Gaps = 6/156 (3%)
Frame = +3
Query: 135 LQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIY-ALEAGYTHIDTAYKYGIEDQ 311
+QL++G +P++ LGT +P V +VT + ++ AL+ GY + DTA +Y E +
Sbjct: 15 VQLNNGYKMPLLGLGT----QPYDIVTRVTVEEMTTLLSNALDFGYRNFDTAKQYRNEVE 70
Query: 312 VGRALTKKFSEG-LKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWP- 485
+G+A F +G KRE +FITTKL+ + +++ ++ SL+ L Y+DLYLI W
Sbjct: 71 IGQAFQNIFQQGKYKREDVFITTKLF-PFKIEKKIKEVVQNSLDQLQTSYIDLYLIQWSF 129
Query: 486 ---IAMFENDTLLDNVDFLDTWRGMIDAKKLGLTKS 584
+ F+ +++ + WR + + +LG+ +S
Sbjct: 130 TPVLTNFDGSVAVNHRPIHEVWRELEECVELGMIRS 165
>UniRef50_Q6F7K7 Cluster: 2,5-diketo-D-gluconate reductase; n=20;
Bacteria|Rep: 2,5-diketo-D-gluconate reductase -
Acinetobacter sp. (strain ADP1)
Length = 297
Score = 81.4 bits (192), Expect = 3e-14
Identities = 57/182 (31%), Positives = 91/182 (50%), Gaps = 1/182 (0%)
Frame = +3
Query: 126 VPTLQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIE 305
+P L L G +IP + GT+ +G DT ++ AL GY +D+A+ Y E
Sbjct: 22 IPDLILHDGHSIPALGFGTYTLKGQQGV------DT---MLRALGHGYRMLDSAFNYENE 72
Query: 306 DQVGRALTKKFSEGLKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWP 485
VG A+ + GL R+ IFIT+KL +H ++ + + +SL + +Y+DLYLIHWP
Sbjct: 73 GAVGAAVRQS---GLLRDEIFITSKLPGRHHAYDKAMETIEESLYRMQFDYLDLYLIHWP 129
Query: 486 IAMFENDTLLDNVDFLDTWRGMIDAKKLGLTKS*ASPTLTRTNPEDHRQRTGEXSAL-QI 662
+++ W+ +IDA+K G +S + E R+ TG + Q+
Sbjct: 130 NP--------QQGLYIEAWQALIDAQKKGYIRSIGVSNFLPKHIETLRRETGVIPVINQV 181
Query: 663 EL 668
EL
Sbjct: 182 EL 183
>UniRef50_A2UAH0 Cluster: Aldo/keto reductase; n=1; Bacillus
coagulans 36D1|Rep: Aldo/keto reductase - Bacillus
coagulans 36D1
Length = 273
Score = 81.4 bits (192), Expect = 3e-14
Identities = 52/149 (34%), Positives = 77/149 (51%), Gaps = 2/149 (1%)
Frame = +3
Query: 132 TLQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQ 311
T L +G IP + LGTW P G+ T AV +AL+ GY HIDTAY Y E+
Sbjct: 7 TFVLENGVAIPKIGLGTW--QVPNGET------TYHAVSFALKNGYRHIDTAYAYHNEES 58
Query: 312 VGRALTKKFSEGLKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIH--WP 485
VG+A+ G+ R IF+T+KL ++ + +++ N LE +DLYLIH WP
Sbjct: 59 VGKAVR---DSGIDRRDIFVTSKLPAEIKSYDKALKTFDETMGNFGLEQLDLYLIHAPWP 115
Query: 486 IAMFENDTLLDNVDFLDTWRGMIDAKKLG 572
+ D +N+ + W+ M + + G
Sbjct: 116 WSEKGADYTKENI---EVWKAMEEIYESG 141
>UniRef50_A0JX62 Cluster: 2,5-didehydrogluconate reductase; n=9;
Bacteria|Rep: 2,5-didehydrogluconate reductase -
Arthrobacter sp. (strain FB24)
Length = 291
Score = 81.4 bits (192), Expect = 3e-14
Identities = 44/102 (43%), Positives = 56/102 (54%), Gaps = 14/102 (13%)
Frame = +3
Query: 228 DTEQAVIYALEAGYTHIDTAYKYGIEDQVGRAL--------------TKKFSEGLKRESI 365
D V ALEAGY H DTA YG E VG+A+ + + + L RE +
Sbjct: 29 DAAGLVTMALEAGYRHFDTAAMYGNETGVGKAIGALAGFAGGGPAGGSGEAAPSLSREDL 88
Query: 366 FITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPIA 491
F+TTK+WN H + + A S+ NL +EYVDLYLIHWP A
Sbjct: 89 FVTTKVWNDDHGYDATMRAFDTSMSNLGMEYVDLYLIHWPCA 130
>UniRef50_A0AWM8 Cluster: Aldo/keto reductase; n=4;
Actinomycetales|Rep: Aldo/keto reductase - Arthrobacter
sp. (strain FB24)
Length = 287
Score = 81.4 bits (192), Expect = 3e-14
Identities = 46/153 (30%), Positives = 81/153 (52%)
Frame = +3
Query: 126 VPTLQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIE 305
+P L+L G IP + LGTW + ++ E AV +AL++GY +DTA++Y E
Sbjct: 13 IPRLKLPHGHTIPRLGLGTW---------PMLEDECETAVRFALQSGYRLVDTAFQYRNE 63
Query: 306 DQVGRALTKKFSEGLKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWP 485
+ VGR + + G+ R +FI++K H + V A +SL L L+++D+++ HWP
Sbjct: 64 EAVGRGIR---TAGVPRSELFISSKFNKESHSIDGVQRAYDESLRKLGLDHLDMFMCHWP 120
Query: 486 IAMFENDTLLDNVDFLDTWRGMIDAKKLGLTKS 584
+ ++D W+G++ + G K+
Sbjct: 121 VPALGK--------YVDAWKGLVKLLEEGRVKA 145
>UniRef50_Q235V6 Cluster: Oxidoreductase, aldo/keto reductase family
protein; n=2; Tetrahymena thermophila SB210|Rep:
Oxidoreductase, aldo/keto reductase family protein -
Tetrahymena thermophila SB210
Length = 332
Score = 81.4 bits (192), Expect = 3e-14
Identities = 50/150 (33%), Positives = 86/150 (57%), Gaps = 1/150 (0%)
Frame = +3
Query: 138 QLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQVG 317
+L++G +P+V LGT+L + + ++TN + AL+AGY HIDTA Y E +G
Sbjct: 9 KLNNGQIMPLVGLGTYLLNSKE----EMTN----LLRTALDAGYRHIDTAVNYQNEAMIG 60
Query: 318 RALTKKFSEG-LKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPIAM 494
+L F EG R+ +FI +K++ + + ++ +++KSL+ L L+YVDLY +H+P+
Sbjct: 61 ESLKTIFKEGKYSRKDLFIVSKVFPN--KGINMLESVKKSLKELQLDYVDLYYLHFPLGF 118
Query: 495 FENDTLLDNVDFLDTWRGMIDAKKLGLTKS 584
++ W + +A +LGL KS
Sbjct: 119 LSEKEEFVHLPVHVAWAQLEEAHRLGLAKS 148
>UniRef50_Q927P9 Cluster: Lin2739 protein; n=12; Bacteria|Rep:
Lin2739 protein - Listeria innocua
Length = 283
Score = 81.0 bits (191), Expect = 4e-14
Identities = 44/118 (37%), Positives = 69/118 (58%)
Frame = +3
Query: 132 TLQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQ 311
T++L++G +P++ GT+ + + EQAV A+ AGY HIDTA Y E+
Sbjct: 3 TVKLNNGIEVPILGFGTYQ--------ITDAGEAEQAVKEAIAAGYRHIDTAQSYMNEEA 54
Query: 312 VGRALTKKFSEGLKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWP 485
VGR + + G+ R+ +FITTK+W + V+ + +SL+ L L+Y+DL LIH P
Sbjct: 55 VGRGIA---ASGVDRKELFITTKIWVENVSYKGVMSSFDRSLKRLGLDYIDLLLIHQP 109
>UniRef50_Q9X265 Cluster: Oxidoreductase, aldo/keto reductase
family; n=2; Thermotoga|Rep: Oxidoreductase, aldo/keto
reductase family - Thermotoga maritima
Length = 274
Score = 80.6 bits (190), Expect = 6e-14
Identities = 46/119 (38%), Positives = 72/119 (60%), Gaps = 6/119 (5%)
Frame = +3
Query: 147 SGGNIPVVALGTW-LGHRPKGKVVQVTNDTEQAVIY--ALEAGYTHIDTAYKYG---IED 308
+G IP + LGTW +G + + D E + A++ GYTHIDTA YG E+
Sbjct: 9 TGEEIPALGLGTWGIGGF---ETPDYSRDEEMVELLKTAIKMGYTHIDTAEYYGGGHTEE 65
Query: 309 QVGRALTKKFSEGLKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWP 485
+G+A+ K F +RE +FI +K+W ++ R+ ++ +L +L+ L+ +YVDLYLIHWP
Sbjct: 66 LIGKAI-KDF----RREDLFIVSKVWPTHLRRDDLLRSLENTLKRLDTDYVDLYLIHWP 119
>UniRef50_Q0SFM4 Cluster: Probable 2,5-didehydrogluconate reductase;
n=1; Rhodococcus sp. RHA1|Rep: Probable
2,5-didehydrogluconate reductase - Rhodococcus sp.
(strain RHA1)
Length = 265
Score = 80.6 bits (190), Expect = 6e-14
Identities = 48/111 (43%), Positives = 65/111 (58%)
Frame = +3
Query: 156 NIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQVGRALTKK 335
+IP + LGTW P D +AV+ +EAGY IDTA Y ED VG AL +
Sbjct: 3 DIPPLGLGTWPLTGP---------DATRAVLSGIEAGYRLIDTATIYDNEDAVGVALAEC 53
Query: 336 FSEGLKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPI 488
G+ RE +F+TTKL S H + A+ +SL+NL L+ +DL+LIHWP+
Sbjct: 54 ---GVPREELFVTTKLRGSDHVSGDIRGAVERSLKNLGLDRLDLFLIHWPL 101
>UniRef50_A3VHZ9 Cluster: Oxidoreductase; n=1; Rhodobacterales
bacterium HTCC2654|Rep: Oxidoreductase - Rhodobacterales
bacterium HTCC2654
Length = 278
Score = 80.6 bits (190), Expect = 6e-14
Identities = 44/119 (36%), Positives = 65/119 (54%)
Frame = +3
Query: 129 PTLQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIED 308
PT+ L++G +P + LGTW ++ +AV A+E GY IDTA Y E
Sbjct: 8 PTVTLANGVEMPQLGLGTW---------PMTDDEAAKAVATAIETGYRLIDTAENYKNET 58
Query: 309 QVGRALTKKFSEGLKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWP 485
VG+ + G+ R+ +F+TTK+ +H + A SLE L L+Y+DL+LIHWP
Sbjct: 59 GVGQGIR---DAGVARDEVFLTTKMNKQWHSVDGARRACEASLERLGLDYIDLFLIHWP 114
>UniRef50_A0JRJ6 Cluster: Aldo/keto reductase; n=2;
Micrococcineae|Rep: Aldo/keto reductase - Arthrobacter
sp. (strain FB24)
Length = 281
Score = 80.6 bits (190), Expect = 6e-14
Identities = 53/122 (43%), Positives = 70/122 (57%), Gaps = 1/122 (0%)
Frame = +3
Query: 126 VPTLQLSSGGNIPVVALGTWLGHRPKGKVVQVT-NDTEQAVIYALEAGYTHIDTAYKYGI 302
+P L L++G IP + G V QV +T++ V ALEAGY HIDTA Y
Sbjct: 9 IPQLTLNNGVKIPQLGFG----------VFQVPPEETQRIVEDALEAGYRHIDTAAAYRN 58
Query: 303 EDQVGRALTKKFSEGLKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHW 482
E VG A++ + G+ RE IFITTKL N E+ A + S + L +E+VDLYLIHW
Sbjct: 59 EAGVGAAIS---ASGIPREDIFITTKLRNG--EQGNAHEAFQNSRKALGVEFVDLYLIHW 113
Query: 483 PI 488
P+
Sbjct: 114 PV 115
>UniRef50_Q8ZH36 Cluster: 2,5-diketo-D-gluconic acid reductase B;
n=91; Proteobacteria|Rep: 2,5-diketo-D-gluconic acid
reductase B - Yersinia pestis
Length = 267
Score = 80.6 bits (190), Expect = 6e-14
Identities = 53/142 (37%), Positives = 81/142 (57%)
Frame = +3
Query: 156 NIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQVGRALTKK 335
+IPV LGT+ R + ++V +V AL GY IDTA Y E VG+A+ +
Sbjct: 2 SIPVFGLGTF---RLQDQIVI------DSVSQALTLGYRAIDTAQIYENEAPVGQAIQES 52
Query: 336 FSEGLKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPIAMFENDTLL 515
G+ R+ +FITTK+W + ++++IP+LR+S++ L +YVDL LIHWP +
Sbjct: 53 ---GINRDELFITTKIWIANLSKDKLIPSLRESIQKLKTDYVDLTLIHWP-------SPN 102
Query: 516 DNVDFLDTWRGMIDAKKLGLTK 581
D V + ++ AK LGLT+
Sbjct: 103 DEVSVAEFMSELLKAKGLGLTR 124
>UniRef50_Q8Y463 Cluster: Lmo2592 protein; n=40; Bacteria|Rep:
Lmo2592 protein - Listeria monocytogenes
Length = 283
Score = 80.2 bits (189), Expect = 8e-14
Identities = 46/120 (38%), Positives = 72/120 (60%), Gaps = 2/120 (1%)
Frame = +3
Query: 132 TLQLSSGGNIPVVALGTWLGHRPKGKVVQVTN--DTEQAVIYALEAGYTHIDTAYKYGIE 305
T++L++G +P++ GT+ Q+T+ + E AV A++AGY HIDTA Y E
Sbjct: 3 TVKLNNGVEVPILGFGTY----------QITDAAEAEHAVKDAIKAGYRHIDTAQSYMNE 52
Query: 306 DQVGRALTKKFSEGLKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWP 485
+ VGR + + G+ R+ +FITTK+W + V+ + +SL+ L L+YVDL LIH P
Sbjct: 53 EAVGRGIA---ASGVDRKELFITTKIWVENVSYKGVMSSFDRSLKRLGLDYVDLLLIHQP 109
>UniRef50_Q838E0 Cluster: Oxidoreductase, aldo/keto reductase
family; n=24; Bacilli|Rep: Oxidoreductase, aldo/keto
reductase family - Enterococcus faecalis (Streptococcus
faecalis)
Length = 279
Score = 80.2 bits (189), Expect = 8e-14
Identities = 46/122 (37%), Positives = 68/122 (55%), Gaps = 1/122 (0%)
Frame = +3
Query: 123 IVPTLQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGI 302
+ T+ L++G IP + LG + P + +V E+ +I GY IDTA YG
Sbjct: 5 LADTVTLNNGTKIPGMGLGVF--QIPDEETAKVV---EEGIIN----GYRLIDTAQIYGN 55
Query: 303 EDQVGRALTKKFSE-GLKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIH 479
E G + + GL RE +F+T+K+WN++ ++ I A SLE L L+Y+DLYLIH
Sbjct: 56 ESGTGAGIKAGLAATGLNREDLFVTSKVWNAHISYDETIQAFNDSLERLGLDYLDLYLIH 115
Query: 480 WP 485
WP
Sbjct: 116 WP 117
>UniRef50_Q05KR9 Cluster: Benzil reductase; n=5; Bacillales|Rep:
Benzil reductase - Bacillus subtilis
Length = 276
Score = 80.2 bits (189), Expect = 8e-14
Identities = 46/118 (38%), Positives = 67/118 (56%)
Frame = +3
Query: 132 TLQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQ 311
T++L +G +P LG + V+ N+ ++V A++ GY IDTA Y E+
Sbjct: 8 TVKLHNGVEMPWFGLGVFK--------VENGNEATESVKAAIKNGYRSIDTAAIYKNEEG 59
Query: 312 VGRALTKKFSEGLKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWP 485
VG + + G+ RE +FIT+K+WN E + A KSLE L L+Y+DLYLIHWP
Sbjct: 60 VGIGIKES---GVAREELFITSKVWNEDQGYETTLAAFEKSLERLQLDYLDLYLIHWP 114
>UniRef50_Q18483 Cluster: Putative uncharacterized protein; n=2;
Caenorhabditis|Rep: Putative uncharacterized protein -
Caenorhabditis elegans
Length = 287
Score = 80.2 bits (189), Expect = 8e-14
Identities = 48/144 (33%), Positives = 76/144 (52%), Gaps = 1/144 (0%)
Frame = +3
Query: 156 NIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQVGRALTKK 335
N+P++ +GTW VQ Q + + GY IDTA Y E ++GR L K
Sbjct: 10 NMPLIGIGTWQ--------VQKEEILRQVIDAGFKEGYRFIDTAQVYNNEAKIGRILEKL 61
Query: 336 F-SEGLKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPIAMFENDTL 512
+ GLKRE I+IT+KL S ++ ++ +SL NL +EY+DL LIHWP + +++
Sbjct: 62 LPANGLKREDIWITSKLAPSNAGVKKARESIEESLSNLKVEYLDLLLIHWPGSSLKSENP 121
Query: 513 LDNVDFLDTWRGMIDAKKLGLTKS 584
+ +++W M + G +S
Sbjct: 122 ANKKLRVESWNVMCEMMAEGKLRS 145
>UniRef50_Q89JN4 Cluster: Oxidoreductase; n=8; Rhizobiales|Rep:
Oxidoreductase - Bradyrhizobium japonicum
Length = 272
Score = 79.8 bits (188), Expect = 1e-13
Identities = 49/147 (33%), Positives = 79/147 (53%), Gaps = 1/147 (0%)
Frame = +3
Query: 144 SSGGNIPVVALGTW-LGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQVGR 320
++G IP + LGTW L RP +VV+ AL GY HIDTA Y E +VG
Sbjct: 6 ANGARIPAIGLGTWELSGRPCARVVE----------QALRLGYRHIDTAQVYDNEREVGD 55
Query: 321 ALTKKFSEGLKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPIAMFE 500
+ + G++R+ +F+TTK+W ++ + ++++SL L L VDL L+HWP +
Sbjct: 56 GVR---ASGVRRDDVFLTTKVWTNHFAPNDLERSVKESLARLRLPSVDLLLLHWPNS--- 109
Query: 501 NDTLLDNVDFLDTWRGMIDAKKLGLTK 581
+V +T + A+++GLT+
Sbjct: 110 ------HVPLAETLGALSHARQMGLTR 130
>UniRef50_A5ZYE6 Cluster: Putative uncharacterized protein; n=1;
Ruminococcus obeum ATCC 29174|Rep: Putative
uncharacterized protein - Ruminococcus obeum ATCC 29174
Length = 263
Score = 79.4 bits (187), Expect = 1e-13
Identities = 41/108 (37%), Positives = 63/108 (58%)
Frame = +3
Query: 228 DTEQAVIYALEAGYTHIDTAYKYGIEDQVGRALTKKFSEGLKRESIFITTKLWNSYHERE 407
+ E A+ A++ GY +DTA Y E+ VG + K G+ R+ +FITTK+WN+
Sbjct: 16 EAEDAIAAAVQNGYRLLDTASAYKNEEFVGCGIAKC---GVPRKDLFITTKIWNNAQRLG 72
Query: 408 QVIPALRKSLENLNLEYVDLYLIHWPIAMFENDTLLDNVDFLDTWRGM 551
V A ++SL+ L L+Y+DLYLIHWP+ +T D L++ R +
Sbjct: 73 DVEGAFQRSLDRLGLDYIDLYLIHWPVPGCFLNTWKDMEKILESGRAL 120
>UniRef50_UPI00006CD296 Cluster: oxidoreductase, aldo/keto reductase
family protein; n=1; Tetrahymena thermophila SB210|Rep:
oxidoreductase, aldo/keto reductase family protein -
Tetrahymena thermophila SB210
Length = 295
Score = 79.0 bits (186), Expect = 2e-13
Identities = 51/152 (33%), Positives = 81/152 (53%), Gaps = 1/152 (0%)
Frame = +3
Query: 132 TLQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQ 311
T +L +G +PV LGT+ KVV + + AL+ GY HIDTA Y E Q
Sbjct: 7 TTELCNGSKLPVFGLGTY-------KVVS-KEEMVTFLRTALDLGYRHIDTAIMYENEKQ 58
Query: 312 VGRALTKKFSEG-LKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPI 488
+G AL + + EG KRE +F+ TKL++ ++ +V +R+SL+NL Y+DLYL+H+
Sbjct: 59 IGDALQEIYKEGKYKREDLFLVTKLFS--NKNTKVEDQVRQSLQNLQTNYIDLYLLHYAS 116
Query: 489 AMFENDTLLDNVDFLDTWRGMIDAKKLGLTKS 584
+ + L + W + + GL ++
Sbjct: 117 SPPTDQFELTHKPVFQVWAEFEELVQKGLIRN 148
>UniRef50_Q9HM42 Cluster: Alcohol dehydrogenase related protein;
n=1; Thermoplasma acidophilum|Rep: Alcohol dehydrogenase
related protein - Thermoplasma acidophilum
Length = 284
Score = 79.0 bits (186), Expect = 2e-13
Identities = 41/113 (36%), Positives = 64/113 (56%)
Frame = +3
Query: 147 SGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQVGRAL 326
+G + V+ +GTW + + V+ ++ YAL+ G IDTA YG ED VG A+
Sbjct: 12 TGRKVSVIGVGTWSLEGSRSENVR-------SIRYALDHGVNFIDTAEMYGTEDIVGEAI 64
Query: 327 TKKFSEGLKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWP 485
+G +RE +FI TK+W ++ V+ + +SL+ L +YVDLY +HWP
Sbjct: 65 -----KGYRREDLFIATKVWPTHFAYHDVLKSCEESLKKLGTDYVDLYQLHWP 112
>UniRef50_Q02198 Cluster: Morphine 6-dehydrogenase; n=5;
Bacteria|Rep: Morphine 6-dehydrogenase - Pseudomonas
putida
Length = 296
Score = 78.6 bits (185), Expect = 2e-13
Identities = 43/119 (36%), Positives = 65/119 (54%)
Frame = +3
Query: 129 PTLQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIED 308
P + L++G +P + LG + +T A+ A+ +GY IDTA Y E
Sbjct: 6 PLINLNNGVKMPALGLGVFAAS---------AEETASAIASAISSGYRLIDTARSYNNEA 56
Query: 309 QVGRALTKKFSEGLKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWP 485
QVG + + G+ R +F+TTKL+N + E+ + A +SL L L+YVDLYL+HWP
Sbjct: 57 QVGEGIR---NSGVDRAEMFVTTKLFNCDYGYERALRAFDESLGRLGLDYVDLYLLHWP 112
>UniRef50_Q1M4Z6 Cluster: Putative aldo-keto reductase/oxidase; n=1;
Rhizobium leguminosarum bv. viciae 3841|Rep: Putative
aldo-keto reductase/oxidase - Rhizobium leguminosarum
bv. viciae (strain 3841)
Length = 274
Score = 78.2 bits (184), Expect = 3e-13
Identities = 40/87 (45%), Positives = 54/87 (62%)
Frame = +3
Query: 225 NDTEQAVIYALEAGYTHIDTAYKYGIEDQVGRALTKKFSEGLKRESIFITTKLWNSYHER 404
++ Q VI+ALEAG HIDTA YG E V R + G+ R IFITTK+ +
Sbjct: 23 DEAHQGVIWALEAGCRHIDTAQGYGNEQDVARGIK---DAGVARNEIFITTKVKPDNYGP 79
Query: 405 EQVIPALRKSLENLNLEYVDLYLIHWP 485
V+P++R+SLE L ++ VDL L+HWP
Sbjct: 80 GAVMPSVRESLEKLRVDQVDLLLLHWP 106
>UniRef50_A5VK30 Cluster: 2,5-didehydrogluconate reductase; n=2;
Lactobacillus reuteri|Rep: 2,5-didehydrogluconate
reductase - Lactobacillus reuteri F275
Length = 300
Score = 78.2 bits (184), Expect = 3e-13
Identities = 52/154 (33%), Positives = 83/154 (53%), Gaps = 2/154 (1%)
Frame = +3
Query: 129 PTLQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIED 308
P ++L++G IP + LG W K + + T+Q V A+ Y IDTA +YG E
Sbjct: 11 PKIKLNNGHLIPQLGLGVW-----KASLAE----TQQMVKEAIMNDYVLIDTAKQYGNEA 61
Query: 309 QVGRALTKKF-SEGLKRESIFITTKLWNSYH-EREQVIPALRKSLENLNLEYVDLYLIHW 482
VG+ + F + G KR+SIF+TTK++N + +++ A+ + L+ L YVDL L+HW
Sbjct: 62 AVGQGIQDGFKATGRKRDSIFLTTKIFNGDQGDYDKLRQAVNEQLKKLQTNYVDLLLLHW 121
Query: 483 PIAMFENDTLLDNVDFLDTWRGMIDAKKLGLTKS 584
P+ N + ++WR + D K G K+
Sbjct: 122 PV----------NDKYNESWRALEDIYKDGQAKA 145
>UniRef50_A7P424 Cluster: Chromosome chr1 scaffold_5, whole genome
shotgun sequence; n=1; Vitis vinifera|Rep: Chromosome
chr1 scaffold_5, whole genome shotgun sequence - Vitis
vinifera (Grape)
Length = 247
Score = 78.2 bits (184), Expect = 3e-13
Identities = 48/126 (38%), Positives = 70/126 (55%), Gaps = 11/126 (8%)
Frame = +3
Query: 240 AVIYALEAGYTHIDTAYKYGIEDQVGRALTKKFSEGL--KRESIFITTKLWNSYHEREQV 413
+++ A+E GY H D Y E +G A+ K GL R+ +FIT+KLW S ++V
Sbjct: 37 SILTAIELGYRHFDCVAAYLSEKPLGEAIKKAVKLGLIKSRDELFITSKLWCSDAHHDRV 96
Query: 414 IPALRKSL---------ENLNLEYVDLYLIHWPIAMFENDTLLDNVDFLDTWRGMIDAKK 566
+PAL+ +L +NL L+Y+DLYLIHW +D L +D W+ M D +K
Sbjct: 97 LPALQNTLKISSILSFSKNLQLDYLDLYLIHW------SDGHLP-IDLGSVWKAMEDFQK 149
Query: 567 LGLTKS 584
L LTK+
Sbjct: 150 LSLTKA 155
>UniRef50_Q76L37 Cluster: Conjugated polyketone reductase C1; n=3;
Saccharomycetales|Rep: Conjugated polyketone reductase
C1 - Candida parapsilosis (Yeast)
Length = 304
Score = 78.2 bits (184), Expect = 3e-13
Identities = 57/160 (35%), Positives = 84/160 (52%), Gaps = 11/160 (6%)
Frame = +3
Query: 138 QLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVI----YALEAGYTHIDTAYKYGIE 305
+LS+G IP VA GT + +G ND ++ +I AL +G+ HID A YG
Sbjct: 9 KLSNGNKIPAVAFGTGTKYFKRGH-----NDLDKQLIGTLELALRSGFRHIDGAEIYGTN 63
Query: 306 DQVGRALTKKFSEGLKRESIFITTKL------WNSYHEREQ-VIPALRKSLENLNLEYVD 464
++G AL + GL R+ +FIT K ++ H + Q AL+ LE+L LEYVD
Sbjct: 64 KEIGIALK---NVGLNRKDVFITDKYNSGNHTYDGKHSKHQNPYNALKADLEDLGLEYVD 120
Query: 465 LYLIHWPIAMFENDTLLDNVDFLDTWRGMIDAKKLGLTKS 584
LYLIH+P ++ D ++ WR + AK GL ++
Sbjct: 121 LYLIHFPYISEKS----HGFDLVEAWRYLERAKNEGLARN 156
>UniRef50_Q0CK00 Cluster: Predicted protein; n=1; Aspergillus
terreus NIH2624|Rep: Predicted protein - Aspergillus
terreus (strain NIH 2624)
Length = 292
Score = 78.2 bits (184), Expect = 3e-13
Identities = 53/152 (34%), Positives = 74/152 (48%)
Frame = +3
Query: 129 PTLQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIED 308
P L L G +P++ GT + + + ALE G+ HID A YG E
Sbjct: 4 PALSLKDGNLVPILGFGTGTAWYKDDPNDPTNPELIEVLKAALEKGFHHIDAADSYGTER 63
Query: 309 QVGRALTKKFSEGLKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPI 488
+VG A+ + G+ RE +FITTK+ + + V AL SLE L L+YVDLYL+H P
Sbjct: 64 EVGIAIRES---GIPREQLFITTKVLEGWKD---VPGALDASLERLQLDYVDLYLLHNPY 117
Query: 489 AMFENDTLLDNVDFLDTWRGMIDAKKLGLTKS 584
+ N T D W+G+ K G +S
Sbjct: 118 -VIPNLT-----DIQSAWKGLEAVKATGKARS 143
>UniRef50_Q7VG53 Cluster: Aldo-keto reductase; n=28; Bacteria|Rep:
Aldo-keto reductase - Helicobacter hepaticus
Length = 292
Score = 77.8 bits (183), Expect = 4e-13
Identities = 54/151 (35%), Positives = 80/151 (52%), Gaps = 3/151 (1%)
Frame = +3
Query: 141 LSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQVGR 320
L++G IP + LGTW R VV E AV A + GY HIDTA YG E VG
Sbjct: 17 LNNGNKIPKLGLGTW---RIDDNVV------EAAVREAFKVGYRHIDTAQAYGNERGVGE 67
Query: 321 ALTKKFSEGLKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWP---IA 491
A+ K +KRE +FIT+K+ Y + + ++ SL+ + L+++DL LIH P +
Sbjct: 68 AVRKS---KIKREELFITSKIRAEYKDYKSASASIDTSLKTMKLDFIDLMLIHSPQPWNS 124
Query: 492 MFENDTLLDNVDFLDTWRGMIDAKKLGLTKS 584
+ D +NV + + + DA+K G +S
Sbjct: 125 FRKGDYFKENV---EVYNALEDAQKAGKVRS 152
>UniRef50_Q4V008 Cluster: Oxidoreductase; n=4; Proteobacteria|Rep:
Oxidoreductase - Xanthomonas campestris pv. campestris
(strain 8004)
Length = 267
Score = 77.8 bits (183), Expect = 4e-13
Identities = 53/142 (37%), Positives = 75/142 (52%)
Frame = +3
Query: 159 IPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQVGRALTKKF 338
+P LGT+ R K +VV +V AL GY IDTA Y E QVG+A+
Sbjct: 3 VPAFGLGTF---RLKDQVVI------DSVRNALALGYRAIDTAQIYDNEAQVGQAIA--- 50
Query: 339 SEGLKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPIAMFENDTLLD 518
G+ R+ +F+TTK+W R+ + P+L++SL L +YVDL LIHWP + D
Sbjct: 51 DAGVPRDQLFVTTKIWVDRFSRDTLQPSLQESLRKLGTDYVDLTLIHWP-------SPKD 103
Query: 519 NVDFLDTWRGMIDAKKLGLTKS 584
V + + DAK GLT++
Sbjct: 104 QVPMREYLEALADAKAQGLTRA 125
>UniRef50_Q3CZS2 Cluster: Oxidoreductase, aldo/keto reductase
family; n=2; Streptococcus agalactiae|Rep:
Oxidoreductase, aldo/keto reductase family -
Streptococcus agalactiae H36B
Length = 245
Score = 77.8 bits (183), Expect = 4e-13
Identities = 39/87 (44%), Positives = 57/87 (65%)
Frame = +3
Query: 228 DTEQAVIYALEAGYTHIDTAYKYGIEDQVGRALTKKFSEGLKRESIFITTKLWNSYHERE 407
+ EQ+V+ AL+ GY IDTA Y E+ VGRA+ K G+ R+ IF+ TKLW E
Sbjct: 30 ECEQSVLDALQVGYRLIDTASGYLNEEAVGRAIKKS---GIPRKEIFVVTKLWIQDASEE 86
Query: 408 QVIPALRKSLENLNLEYVDLYLIHWPI 488
+ PA+ ++L+ L L+Y++LYLIH P+
Sbjct: 87 KAGPAIDRALKRLQLDYINLYLIHQPM 113
>UniRef50_A3UJS6 Cluster: Oxidoreductase; n=3;
Alphaproteobacteria|Rep: Oxidoreductase - Oceanicaulis
alexandrii HTCC2633
Length = 275
Score = 77.8 bits (183), Expect = 4e-13
Identities = 42/115 (36%), Positives = 61/115 (53%)
Frame = +3
Query: 144 SSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQVGRA 323
++G +IP + GTW D + V AL+ GY HIDTA YG E VG
Sbjct: 7 ANGADIPKLGFGTWQLE---------DEDAARGVATALKTGYRHIDTAQIYGNEAAVGDG 57
Query: 324 LTKKFSEGLKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPI 488
+ G+KRE F+TTK+W + ++++SL+ L +YVDL L+HWP+
Sbjct: 58 WKQS---GVKREDFFLTTKVWRDKFRDGDLQASVKESLDKLKTDYVDLLLLHWPV 109
>UniRef50_Q7PM68 Cluster: ENSANGP00000014386; n=1; Anopheles gambiae
str. PEST|Rep: ENSANGP00000014386 - Anopheles gambiae
str. PEST
Length = 310
Score = 77.8 bits (183), Expect = 4e-13
Identities = 47/131 (35%), Positives = 71/131 (54%), Gaps = 12/131 (9%)
Frame = +3
Query: 228 DTEQAVIYALEAGYTHIDTAYKYGIEDQVGRALTKKFSE--GLKRESIFITTKLWNSYHE 401
D ++A+ A++ GY DTA YG E VG A+ +K E L R+ FI +KL SYH
Sbjct: 31 DGKEAIRTAIDVGYRMFDTAVAYGNEAIVGEAIREKIRECNNLTRDDFFIISKLSGSYHR 90
Query: 402 REQVIPALRKSLENLNLEYVDLYLIHWPIAM------FENDTLLDNVDF----LDTWRGM 551
++ V R +L+ L ++YVDLYL+H P+A+ N T L+ +D + W G+
Sbjct: 91 QDLVEKCCRMTLDRLGMDYVDLYLMHTPVALQSEKKCARNGTKLNAIDDSIAPTEAWIGL 150
Query: 552 IDAKKLGLTKS 584
+ GL +S
Sbjct: 151 EQCYQEGLCRS 161
>UniRef50_A2QL02 Cluster: Putative frameshift; n=1; Aspergillus
niger|Rep: Putative frameshift - Aspergillus niger
Length = 357
Score = 77.8 bits (183), Expect = 4e-13
Identities = 56/162 (34%), Positives = 79/162 (48%), Gaps = 11/162 (6%)
Frame = +3
Query: 132 TLQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQ 311
T L++G IP + +GT+ Q + E+ V L+ G IDTA YG+E Q
Sbjct: 37 TYTLNTGAKIPALGVGTF----------QDPDSQEETVCQVLQRGMRLIDTARVYGVEQQ 86
Query: 312 VGRALTKKFSEGLKRESIFITTKLW-NSYHEREQVIPALRKSLENLNLEYVDLYLIHWPI 488
VGR + K G+ RE IF+ TKLW N +H + V A+ SL +L YVDL L+H+P
Sbjct: 87 VGRGIKKS---GVPREEIFLGTKLWCNDFHP-DDVERAVDDSLRDLYTPYVDLLLMHYPC 142
Query: 489 AM------FENDT----LLDNVDFLDTWRGMIDAKKLGLTKS 584
F D + F+DTWR + K G ++
Sbjct: 143 TFKRGEDRFPRDAEGRMIHGETTFVDTWRALEKVVKTGKVRA 184
>UniRef50_Q6U5V3 Cluster: Putative uncharacterized protein; n=1;
Klebsiella pneumoniae|Rep: Putative uncharacterized
protein - Klebsiella pneumoniae
Length = 279
Score = 77.4 bits (182), Expect = 6e-13
Identities = 51/148 (34%), Positives = 82/148 (55%), Gaps = 1/148 (0%)
Frame = +3
Query: 228 DTEQAVIYALEAGYTHIDTAYKYGIEDQVGRALTKKFSEGLKRESIFITTKLWNSYHERE 407
D + + AL+AG+ H DTA Y ED VGRAL +++E + RE +FIT+K+
Sbjct: 28 DVDSLIRQALKAGFRHFDTAQAYFNEDGVGRAL--RYTE-VPREQLFITSKIRGRDMGYA 84
Query: 408 QVIPALRKSLENLNLEYVDLYLIHWPIAMFENDTLLDNVDFLDTWRGMIDAKKLGLTKS* 587
+ + + ++LE L +EY++L+LIHWPI N+ +++TW I+ + GL +S
Sbjct: 85 RTLVSFNETLERLGVEYLELFLIHWPIP-------AKNL-YVETWEASIELEASGLIRSI 136
Query: 588 ASPTLTRTNPEDHRQRTGEXSAL-QIEL 668
T + E + TG A+ Q+EL
Sbjct: 137 GVSNFTCQHIERLIEDTGVVPAVNQLEL 164
>UniRef50_A6NPD6 Cluster: Putative uncharacterized protein; n=3;
Bacteria|Rep: Putative uncharacterized protein -
Bacteroides capillosus ATCC 29799
Length = 287
Score = 77.4 bits (182), Expect = 6e-13
Identities = 53/151 (35%), Positives = 78/151 (51%), Gaps = 3/151 (1%)
Frame = +3
Query: 141 LSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIY-ALEAGYTHIDTAYKYGIEDQVG 317
LS+G +IP V GT+ T D + AV+ A+ GY H DTA YG E +G
Sbjct: 10 LSNGLSIPAVGFGTYK-----------TGDGDSAVLSNAIAQGYRHFDTASFYGTETALG 58
Query: 318 RALTKKFSEGLKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPIAMF 497
+A+ + + RE F+T+KLW + + + A +LE L +Y+DLYLIHWP
Sbjct: 59 QAVAES---DIPREDFFLTSKLWKTEMGYDAALRAFDATLERLGTDYLDLYLIHWP---- 111
Query: 498 ENDTLLDNVDFLD--TWRGMIDAKKLGLTKS 584
D L++ LD TWR + + GL ++
Sbjct: 112 RPDLELEDWAKLDRETWRALERLYESGLVRA 142
>UniRef50_A7RRF6 Cluster: Predicted protein; n=2; Nematostella
vectensis|Rep: Predicted protein - Nematostella
vectensis
Length = 275
Score = 77.4 bits (182), Expect = 6e-13
Identities = 43/118 (36%), Positives = 68/118 (57%)
Frame = +3
Query: 231 TEQAVIYALEAGYTHIDTAYKYGIEDQVGRALTKKFSEGLKRESIFITTKLWNSYHEREQ 410
T+QAV++ALE GY IDTA Y E +VG AL + + R +++ TK++++ H E+
Sbjct: 30 TKQAVLWALENGYRMIDTAASYNNEKRVGEALRES---AVPRSEVYLVTKVYHTDHGYEK 86
Query: 411 VIPALRKSLENLNLEYVDLYLIHWPIAMFENDTLLDNVDFLDTWRGMIDAKKLGLTKS 584
+ A +SL L ++YVDLYLIH+P+ + +W M + + GLT+S
Sbjct: 87 TMKAYDRSLSALGVDYVDLYLIHFPVP----------AGVVGSWEAMAELQGKGLTRS 134
>UniRef50_UPI0000499B0E Cluster: oxidoreductase, aldo/keto reductase
family; n=1; Entamoeba histolytica HM-1:IMSS|Rep:
oxidoreductase, aldo/keto reductase family - Entamoeba
histolytica HM-1:IMSS
Length = 307
Score = 77.0 bits (181), Expect = 7e-13
Identities = 52/155 (33%), Positives = 79/155 (50%), Gaps = 7/155 (4%)
Frame = +3
Query: 141 LSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQVGR 320
L++G +P + LGTWL + +AV ALE GY ID A Y E ++G
Sbjct: 8 LNNGKFMPAIGLGTWLA---------APGEVGKAVTLALENGYRLIDCARFYKNEKEIGE 58
Query: 321 ALTKKFSEGLKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPIAMF- 497
+ F + RE +F+T+KLW R + + +S+++L +Y+DLYLIHWPIA+
Sbjct: 59 MGIEPFLKNHPREELFVTSKLWMDQVTR--IRESCLESIQDLKCKYLDLYLIHWPIALKV 116
Query: 498 ------ENDTLLDNVDFLDTWRGMIDAKKLGLTKS 584
+ + LD +D + W+ M GL KS
Sbjct: 117 DASNPPKPEDFLD-MDITEIWQEMERLVDEGLVKS 150
>UniRef50_Q14LU6 Cluster: Putative aldo/keto reductase
oxidoreductase protein; n=1; Spiroplasma citri|Rep:
Putative aldo/keto reductase oxidoreductase protein -
Spiroplasma citri
Length = 138
Score = 77.0 bits (181), Expect = 7e-13
Identities = 41/114 (35%), Positives = 70/114 (61%)
Frame = +3
Query: 135 LQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQV 314
L+L +G IP++ LGT+ K+ ++ QA+I AL+ GY HIDTA YG E+ +
Sbjct: 8 LKLFNGVEIPLIGLGTY-------KMTD-EHEVYQAIITALQNGYRHIDTAQIYGNEELI 59
Query: 315 GRALTKKFSEGLKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLI 476
G+A+ G+ R+ IF+T+K+WN+ H+ + + + L+ L+ +Y+DL L+
Sbjct: 60 GKAIK---DSGVPRKEIFLTSKIWNANHKYDAALQEIDNILKRLDTDYLDLCLV 110
>UniRef50_Q572D2 Cluster: Aldo-keto reductase, putative; n=1;
Phytophthora infestans|Rep: Aldo-keto reductase,
putative - Phytophthora infestans (Potato late blight
fungus)
Length = 255
Score = 77.0 bits (181), Expect = 7e-13
Identities = 45/120 (37%), Positives = 67/120 (55%)
Frame = +3
Query: 126 VPTLQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIE 305
VPT L SG IP++ LG + + +T A++ +L+ GY HIDTA YG E
Sbjct: 5 VPTKILPSGARIPMIGLGVYQS--------EPGPETYNAILTSLKLGYRHIDTAEIYGNE 56
Query: 306 DQVGRALTKKFSEGLKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWP 485
+ VGRA+ G+ RE IF+TTKL+ + + + A + S + L + Y+ LYL+H P
Sbjct: 57 EDVGRAVR---DSGIPREEIFVTTKLFTTNWGYSKALAAGKASNDRLGIVYIYLYLLHAP 113
>UniRef50_UPI00015B5BD7 Cluster: PREDICTED: similar to aldo-keto
reductase; n=1; Nasonia vitripennis|Rep: PREDICTED:
similar to aldo-keto reductase - Nasonia vitripennis
Length = 310
Score = 76.6 bits (180), Expect = 1e-12
Identities = 50/153 (32%), Positives = 89/153 (58%), Gaps = 3/153 (1%)
Frame = +3
Query: 135 LQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQV 314
L+L++G ++P+V +GT+ + +G+ V ++ + + G+ IDTA Y E+ +
Sbjct: 26 LRLNNGYDMPLVGIGTY---KVRGREV-----IKRVIDESFAVGFRSIDTAVVYRNEEDI 77
Query: 315 GRALTKKFSE-GLKRESIFITTKLWNSYH-EREQVIPALRKSLENLNLEYVDLYLIHWPI 488
G AL + + LKRE IFIT+KL S + + +++ ++ SL+ L+ Y+DLYLIHWP
Sbjct: 78 GLALKELLPKYNLKREDIFITSKLSPSDNGDPDKIRKSVEDSLKALDTSYLDLYLIHWPG 137
Query: 489 AMFENDTLLDNVDF-LDTWRGMIDAKKLGLTKS 584
A + DN + TW +++ ++ GL +S
Sbjct: 138 ASRILENSPDNPKLRVTTWATLVELQQKGLLRS 170
>UniRef50_Q5FKI1 Cluster: Reductase-dehydrogenase; n=1;
Lactobacillus acidophilus|Rep: Reductase-dehydrogenase -
Lactobacillus acidophilus
Length = 271
Score = 76.6 bits (180), Expect = 1e-12
Identities = 52/151 (34%), Positives = 75/151 (49%), Gaps = 3/151 (1%)
Frame = +3
Query: 141 LSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVI-YALEAGYTHIDTAYKYGIEDQVG 317
L++G IP + LGTWL + ND V+ A+ GY DTA YG E VG
Sbjct: 9 LNNGEKIPQIQLGTWL----------INNDEVNKVVRQAVNIGYRGFDTAKDYGNESGVG 58
Query: 318 RALTKKFSEGLKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPIAMF 497
+ + ++ ++R IF+TTKL + + E A+ +L+ LEY+DL LIH P
Sbjct: 59 KGI---WNSDIERSDIFLTTKLPTAVKDYEGTKKAIDAALDKFGLEYIDLLLIHSPQPWI 115
Query: 498 ENDTLLDN--VDFLDTWRGMIDAKKLGLTKS 584
E + D L+ WR M +A K G +S
Sbjct: 116 EVNRTNDRHFKGNLENWRAMEEAVKAGKVRS 146
>UniRef50_Q3E9M9 Cluster: Uncharacterized protein At5g01670.2; n=7;
Magnoliophyta|Rep: Uncharacterized protein At5g01670.2 -
Arabidopsis thaliana (Mouse-ear cress)
Length = 349
Score = 76.6 bits (180), Expect = 1e-12
Identities = 63/194 (32%), Positives = 93/194 (47%), Gaps = 34/194 (17%)
Frame = +3
Query: 105 FTSADLIVPTLQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYAL-EAGYTHID 281
FTS + + +L SG IP V LGTW + + AV+ A+ E GY HID
Sbjct: 6 FTSEGQNMESFRLLSGHKIPAVGLGTW----------RSGSQAAHAVVTAIVEGGYRHID 55
Query: 282 TAYKYGIEDQVGRALTKKFSEGLKRESIFITTKLWNSYHEREQV---IPAL--------- 425
TA++YG + +VG+ + + GL+R +F+T+KLW + R+ + P +
Sbjct: 56 TAWEYGDQREVGQGIKRAMHAGLERRDLFVTSKLWYTLILRKMINLSSPLMNVLVGTCLN 115
Query: 426 -----------RKSLEN----LNLEYVDLYLIHWPIAMFENDTLLDNV-DFLD-----TW 542
R +L+N L LEY+DLYLIHWPI + E + D LD W
Sbjct: 116 KRCTELSPERVRPALQNTLKELQLEYLDLYLIHWPIRLREGASKPPKAGDVLDFDMEGVW 175
Query: 543 RGMIDAKKLGLTKS 584
R M + K L ++
Sbjct: 176 REMENLSKDSLVRN 189
>UniRef50_Q5B5R6 Cluster: Putative uncharacterized protein; n=1;
Emericella nidulans|Rep: Putative uncharacterized
protein - Emericella nidulans (Aspergillus nidulans)
Length = 682
Score = 76.6 bits (180), Expect = 1e-12
Identities = 54/141 (38%), Positives = 76/141 (53%)
Frame = +3
Query: 132 TLQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQ 311
+ +L++G IP V LGT +P G V + AV AL+ GY HIDTA G+E +
Sbjct: 413 SFRLNTGALIPAVGLGTRRAQKP-GLVYR-------AVRSALKTGYRHIDTAMSSGVEHE 464
Query: 312 VGRALTKKFSEGLKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPIA 491
+G+A+ G+ R +++TTKL N +H R Q AL SL L ++YVDLYL
Sbjct: 465 IGQAVK---DSGVSRSQVWVTTKLDNRWHTRVQ--EALDMSLSELGMDYVDLYL------ 513
Query: 492 MFENDTLLDNVDFLDTWRGMI 554
+L + DF+ TW G I
Sbjct: 514 ------MLADWDFVKTWYGKI 528
>UniRef50_Q9A2X8 Cluster: Oxidoreductase, aldo/keto reductase
family; n=3; Caulobacter|Rep: Oxidoreductase, aldo/keto
reductase family - Caulobacter crescentus (Caulobacter
vibrioides)
Length = 279
Score = 75.8 bits (178), Expect = 2e-12
Identities = 47/122 (38%), Positives = 66/122 (54%), Gaps = 1/122 (0%)
Frame = +3
Query: 123 IVPTLQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIY-ALEAGYTHIDTAYKYG 299
+VP ++ S +P + GTW Q+ N T ++ ALE GY HIDTA YG
Sbjct: 4 LVPAVR-SGDVLMPALGFGTW----------QLENGTAVPLVEKALEIGYRHIDTAQIYG 52
Query: 300 IEDQVGRALTKKFSEGLKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIH 479
E VG A+ + G+KR+ IF+TTK+W + + KSLE L ++ VDL L+H
Sbjct: 53 NERDVGAAIR---NSGVKRDEIFLTTKVWIDQFADGDLQRSAEKSLEKLGVDQVDLLLLH 109
Query: 480 WP 485
WP
Sbjct: 110 WP 111
>UniRef50_Q979I4 Cluster: Aldo / keto reductase; n=3; Archaea|Rep:
Aldo / keto reductase - Thermoplasma volcanium
Length = 288
Score = 75.8 bits (178), Expect = 2e-12
Identities = 40/83 (48%), Positives = 54/83 (65%)
Frame = +3
Query: 237 QAVIYALEAGYTHIDTAYKYGIEDQVGRALTKKFSEGLKRESIFITTKLWNSYHEREQVI 416
QA+ A++AG T IDTA YG ED V +A+ EG RE +FI TK+W ++ ++VI
Sbjct: 50 QAIRTAIDAGVTLIDTAEIYGSEDLVAKAI-----EGHNREELFIATKVWINHLRYDKVI 104
Query: 417 PALRKSLENLNLEYVDLYLIHWP 485
A + SL LN +YVDLY IH+P
Sbjct: 105 KACKASLSRLNTKYVDLYQIHFP 127
>UniRef50_Q5UX52 Cluster: Oxidoreductase aldo/keto reductase family;
n=1; Haloarcula marismortui|Rep: Oxidoreductase
aldo/keto reductase family - Haloarcula marismortui
(Halobacterium marismortui)
Length = 274
Score = 75.8 bits (178), Expect = 2e-12
Identities = 45/113 (39%), Positives = 61/113 (53%), Gaps = 1/113 (0%)
Frame = +3
Query: 150 GGNIPVVALGTWLGHRPKGKVVQVTNDT-EQAVIYALEAGYTHIDTAYKYGIEDQVGRAL 326
G ++P + LGTW Q+T + + V AL GY HIDTA YG E QVG +
Sbjct: 8 GTSVPALGLGTW----------QLTGQSCRETVETALGMGYRHIDTAQAYGNERQVGLGM 57
Query: 327 TKKFSEGLKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWP 485
+ + RE +F+TTKL S + V + R+SL L +Y+DL LIHWP
Sbjct: 58 D---AAAVDREDVFLTTKLDGSNRDERSVRRSTRESLNKLGTDYLDLLLIHWP 107
>UniRef50_Q2CAL9 Cluster: 2,5-didehydrogluconate reductase; n=2;
Oceanicola granulosus HTCC2516|Rep:
2,5-didehydrogluconate reductase - Oceanicola granulosus
HTCC2516
Length = 275
Score = 75.4 bits (177), Expect = 2e-12
Identities = 36/86 (41%), Positives = 54/86 (62%)
Frame = +3
Query: 228 DTEQAVIYALEAGYTHIDTAYKYGIEDQVGRALTKKFSEGLKRESIFITTKLWNSYHERE 407
D A++ ALE GY H+DTA Y E +VG A+ + GL RE++F+TTK+ +
Sbjct: 26 DGISAILCALETGYRHLDTAQDYDTEAEVGEAIRRA---GLPREALFVTTKVRPANFGPG 82
Query: 408 QVIPALRKSLENLNLEYVDLYLIHWP 485
++P++ +SLE + L+ DL LIHWP
Sbjct: 83 DLVPSVARSLETMGLDRADLVLIHWP 108
>UniRef50_Q1RFP0 Cluster: 2,5-diketo-D-gluconic acid reductase A;
n=21; Bacteria|Rep: 2,5-diketo-D-gluconic acid reductase
A - Escherichia coli (strain UTI89 / UPEC)
Length = 294
Score = 75.4 bits (177), Expect = 2e-12
Identities = 50/129 (38%), Positives = 69/129 (53%), Gaps = 4/129 (3%)
Frame = +3
Query: 210 VVQVTNDT--EQAVIYALEAGYTHIDTAYKYGIEDQVGRALTKKFSEGL-KRESIFITTK 380
V QVT+ +Q+V+ A+ GY IDTA YG ED VG A+ + SEGL RE +FIT+K
Sbjct: 24 VFQVTDKDVCKQSVLNAIRTGYRLIDTAAVYGNEDAVGEAVREAISEGLCTREELFITSK 83
Query: 381 LWNSYHEREQVIPA-LRKSLENLNLEYVDLYLIHWPIAMFENDTLLDNVDFLDTWRGMID 557
LW + + A + SL+ LEY DLYL+H + D+ WR + D
Sbjct: 84 LWVQDMLNQDIAAAGIEASLKKSGLEYFDLYLLHQAMR-----------DYFSAWRALED 132
Query: 558 AKKLGLTKS 584
A + G K+
Sbjct: 133 AYEEGKLKA 141
>UniRef50_A7ALH6 Cluster: Putative uncharacterized protein; n=1;
Parabacteroides merdae ATCC 43184|Rep: Putative
uncharacterized protein - Parabacteroides merdae ATCC
43184
Length = 301
Score = 75.4 bits (177), Expect = 2e-12
Identities = 43/121 (35%), Positives = 69/121 (57%)
Frame = +3
Query: 126 VPTLQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIE 305
VPT++L++G +P + +GT+L V ++ + V +A++ G+ IDTA YG E
Sbjct: 29 VPTVKLNNGMEMPQLGVGTFL----------VKDNAAERVCHAIKVGFRLIDTAQGYGNE 78
Query: 306 DQVGRALTKKFSEGLKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWP 485
+VG + + G+ R +FITTK+ V +L KSL +L +Y+DL LIHWP
Sbjct: 79 KEVGEGICRS---GIDRRELFITTKVNTMEMRGGTVRQSLDKSLADLGTDYIDLVLIHWP 135
Query: 486 I 488
+
Sbjct: 136 V 136
>UniRef50_A0L1A2 Cluster: Aldo/keto reductase; n=8;
Gammaproteobacteria|Rep: Aldo/keto reductase -
Shewanella sp. (strain ANA-3)
Length = 280
Score = 75.4 bits (177), Expect = 2e-12
Identities = 46/119 (38%), Positives = 65/119 (54%)
Frame = +3
Query: 225 NDTEQAVIYALEAGYTHIDTAYKYGIEDQVGRALTKKFSEGLKRESIFITTKLWNSYHER 404
N AV+ ALE G HIDTA YG E VG A+ + G+ RE +FITTK+W +
Sbjct: 30 NAAFDAVLMALEEGSRHIDTAQIYGNEQAVGDAIN---TSGIPREELFITTKVWTENLTK 86
Query: 405 EQVIPALRKSLENLNLEYVDLYLIHWPIAMFENDTLLDNVDFLDTWRGMIDAKKLGLTK 581
E+ ++ SL L +Y+DL LIHWP+ N V++L + ++D GLT+
Sbjct: 87 ERFETSVIDSLTALQTKYLDLLLIHWPL----NSDEPSMVEYLSELKAVLDK---GLTR 138
>UniRef50_Q7NB44 Cluster: ARA1; n=3; Firmicutes|Rep: ARA1 -
Mycoplasma gallisepticum
Length = 289
Score = 74.9 bits (176), Expect = 3e-12
Identities = 46/107 (42%), Positives = 61/107 (57%)
Frame = +3
Query: 231 TEQAVIYALEAGYTHIDTAYKYGIEDQVGRALTKKFSEGLKRESIFITTKLWNSYHEREQ 410
T +AV ALE GY H+D A Y E+Q+ + K S G+ R+ IFIT+K+WN E
Sbjct: 38 TVEAVKTALEVGYRHLDCAEIY--ENQLSVSQGIKLS-GVNRKEIFITSKIWNDDKGYES 94
Query: 411 VIPALRKSLENLNLEYVDLYLIHWPIAMFENDTLLDNVDFLDTWRGM 551
A K L++L+LEY+DL LIHWPI D V+ TW+ M
Sbjct: 95 TKKAFHKILKDLDLEYLDLLLIHWPIGKGFKDN-WQEVN-AQTWKAM 139
>UniRef50_Q1PV10 Cluster: Putative uncharacterized protein; n=1;
Candidatus Kuenenia stuttgartiensis|Rep: Putative
uncharacterized protein - Candidatus Kuenenia
stuttgartiensis
Length = 284
Score = 74.9 bits (176), Expect = 3e-12
Identities = 51/137 (37%), Positives = 74/137 (54%), Gaps = 6/137 (4%)
Frame = +3
Query: 141 LSSGGNIPVVALGTW-LGHRPKGKVVQVTNDTEQ--AVIYALEAGYTHIDTAYKYG---I 302
LS+ IPV+ LGTW +G G T D E A+ A++ G THID A Y
Sbjct: 6 LSNNIKIPVIGLGTWTIGG---GDEADTTYDKENISAIKTAIKLGITHIDNAEAYAQGHS 62
Query: 303 EDQVGRALTKKFSEGLKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHW 482
E+ VGRA+ GL R+S+FIT+K+ + + ++ + + SL+ LN +Y+DLYLIH
Sbjct: 63 EELVGRAIV-----GLDRKSLFITSKVSPEHLSYDNLLASAKGSLQRLNTDYIDLYLIHA 117
Query: 483 PIAMFENDTLLDNVDFL 533
P + +DFL
Sbjct: 118 PNPDIPIQETMKAMDFL 134
>UniRef50_Q03U37 Cluster: Aldo/keto reductase of diketogulonate
reductase family; n=5; Lactobacillus|Rep: Aldo/keto
reductase of diketogulonate reductase family -
Lactobacillus brevis (strain ATCC 367 / JCM 1170)
Length = 282
Score = 74.9 bits (176), Expect = 3e-12
Identities = 54/154 (35%), Positives = 78/154 (50%)
Frame = +3
Query: 123 IVPTLQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGI 302
I T +L+ G +PV+ GT+L + Q T +T A+ A +AGY DTA Y
Sbjct: 6 ITATRKLADGRQMPVMGFGTYLLND------QPTMNT--AIQTAWDAGYRMFDTAMLYRN 57
Query: 303 EDQVGRALTKKFSEGLKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHW 482
ED +G A+ + GL RE +F+T+K+ +Q + A+ SL+ L +Y+DL LIHW
Sbjct: 58 EDILGPAIQQL---GLPREGLFLTSKVAEIVQGYDQTMKAVEGSLKRLQTDYLDLLLIHW 114
Query: 483 PIAMFENDTLLDNVDFLDTWRGMIDAKKLGLTKS 584
P+ F DTWR + K G KS
Sbjct: 115 PV----------REHFFDTWRALEQLKADGQVKS 138
>UniRef50_Q15NA5 Cluster: Aldo/keto reductase; n=2;
Gammaproteobacteria|Rep: Aldo/keto reductase -
Pseudoalteromonas atlantica (strain T6c / BAA-1087)
Length = 273
Score = 74.5 bits (175), Expect = 4e-12
Identities = 36/87 (41%), Positives = 54/87 (62%)
Frame = +3
Query: 225 NDTEQAVIYALEAGYTHIDTAYKYGIEDQVGRALTKKFSEGLKRESIFITTKLWNSYHER 404
+D + AV AL+ GY HIDTA Y E +VG A++ + + R +F+TTK+W
Sbjct: 24 DDAKLAVENALDVGYRHIDTAQAYENEAEVGDAIS---ASKISRGELFVTTKVWFDNLSA 80
Query: 405 EQVIPALRKSLENLNLEYVDLYLIHWP 485
++ I +++ SL LN +YVDL L+HWP
Sbjct: 81 DKFITSVQNSLTQLNTDYVDLLLVHWP 107
>UniRef50_Q043M4 Cluster: Aldo/keto reductase of diketogulonate
reductase family; n=2; Lactobacillus|Rep: Aldo/keto
reductase of diketogulonate reductase family -
Lactobacillus gasseri (strain ATCC 33323 / DSM 20243)
Length = 273
Score = 74.5 bits (175), Expect = 4e-12
Identities = 47/120 (39%), Positives = 66/120 (55%)
Frame = +3
Query: 225 NDTEQAVIYALEAGYTHIDTAYKYGIEDQVGRALTKKFSEGLKRESIFITTKLWNSYHER 404
+ T+QAV+ A E GY IDTA Y E QVG A+ + GL R+ +FITTK +E
Sbjct: 25 DQTKQAVLSAFEEGYRLIDTAQYYQNEQQVGEAVK---ASGLNRDEVFITTKTMTDGYED 81
Query: 405 EQVIPALRKSLENLNLEYVDLYLIHWPIAMFENDTLLDNVDFLDTWRGMIDAKKLGLTKS 584
++ L +SL + L+Y DL LIHWP+ +D +DTW + A K G T++
Sbjct: 82 TKI--GLDESLRRIGLDYFDLVLIHWPMG---HD--------IDTWHALEAAYKAGKTRA 128
>UniRef50_O13848 Cluster: NADH/NADPH dependent indole-3-acetaldehyde
reductase AKR3C2; n=1; Schizosaccharomyces pombe|Rep:
NADH/NADPH dependent indole-3-acetaldehyde reductase
AKR3C2 - Schizosaccharomyces pombe (Fission yeast)
Length = 284
Score = 74.5 bits (175), Expect = 4e-12
Identities = 49/142 (34%), Positives = 74/142 (52%)
Frame = +3
Query: 159 IPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQVGRALTKKF 338
+P +GT L + KG++ + D+ V AL AG+ HID A YG E++VG AL +
Sbjct: 12 VPAYGVGTALFKKEKGEINRTIVDS---VKNALAAGFIHIDCAEVYGNEEEVGVALKEA- 67
Query: 339 SEGLKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPIAMFENDTLLD 518
+ R +FIT+K+ H + + AL +SL L +Y+DLYL+H PI +E
Sbjct: 68 --NVPRSKLFITSKVM---HNVDNIPEALNESLRKLGTDYLDLYLLHSPIPFYEK----- 117
Query: 519 NVDFLDTWRGMIDAKKLGLTKS 584
+ + W+ M A GL S
Sbjct: 118 KIPISEGWKAMETALGTGLVHS 139
>UniRef50_Q5V663 Cluster: Aldehyde reductase; n=6;
Halobacteriaceae|Rep: Aldehyde reductase - Haloarcula
marismortui (Halobacterium marismortui)
Length = 279
Score = 74.5 bits (175), Expect = 4e-12
Identities = 46/133 (34%), Positives = 67/133 (50%)
Frame = +3
Query: 159 IPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQVGRALTKKF 338
+P++ LGTW + ++V ALEAGY HIDTA Y E VG +
Sbjct: 17 MPMLGLGTWQN--------EDAEQCAESVRTALEAGYRHIDTAQAYDNESAVGDGIA--- 65
Query: 339 SEGLKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPIAMFENDTLLD 518
+ + R+ IF+ TK+W S + VI +SL+ L ++ VDL +HW +E + L
Sbjct: 66 AADVDRDDIFLATKVWISNLSHDDVIETTEESLDKLGVDSVDLLYVHWAAGEYEPEETLP 125
Query: 519 NVDFLDTWRGMID 557
D L RG+ID
Sbjct: 126 AFDEL-VDRGLID 137
>UniRef50_Q5XJM7 Cluster: Zgc:101765; n=5; Eumetazoa|Rep: Zgc:101765
- Danio rerio (Zebrafish) (Brachydanio rerio)
Length = 288
Score = 73.7 bits (173), Expect = 7e-12
Identities = 49/120 (40%), Positives = 68/120 (56%), Gaps = 1/120 (0%)
Frame = +3
Query: 129 PTLQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIED 308
P++ L++ +P++ LGT+ R +G+ DT AV AL+AGY DTA Y E
Sbjct: 6 PSVLLNNDIQMPLLGLGTF---RLQGQ-----EDTYSAVDAALKAGYRAFDTAAVYRNEA 57
Query: 309 QVGRALTKKFSE-GLKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWP 485
+G AL + GL RE +FIT+KL + + +KSLE L L Y+DLYLIHWP
Sbjct: 58 HLGHALRCLLPKHGLSREDVFITSKL-GPKDQGSKARNGCQKSLEQLGLGYIDLYLIHWP 116
>UniRef50_Q11DV1 Cluster: Aldo/keto reductase; n=10;
Alphaproteobacteria|Rep: Aldo/keto reductase -
Mesorhizobium sp. (strain BNC1)
Length = 274
Score = 73.7 bits (173), Expect = 7e-12
Identities = 35/86 (40%), Positives = 54/86 (62%)
Frame = +3
Query: 228 DTEQAVIYALEAGYTHIDTAYKYGIEDQVGRALTKKFSEGLKRESIFITTKLWNSYHERE 407
+ E+ + ALEAG+ H DTA Y E +GRAL + G +RE +F+TTK+W + +
Sbjct: 25 EVERIIPAALEAGFRHFDTAQIYQNEAALGRALERA---GARREDLFLTTKVWVDNYSAD 81
Query: 408 QVIPALRKSLENLNLEYVDLYLIHWP 485
+ ++ +SLE L ++ VDL L+HWP
Sbjct: 82 KFAASVDESLEKLKVDQVDLLLLHWP 107
>UniRef50_Q03BE0 Cluster: Aldo/keto reductase family enzyme; n=5;
Lactobacillus|Rep: Aldo/keto reductase family enzyme -
Lactobacillus casei (strain ATCC 334)
Length = 281
Score = 73.7 bits (173), Expect = 7e-12
Identities = 38/111 (34%), Positives = 63/111 (56%)
Frame = +3
Query: 150 GGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQVGRALT 329
G N+P++ +GTW + +G Q + A+ Y L G T IDTA YG + +L
Sbjct: 8 GVNVPIMGMGTW--YLGEGNAAQSEQEAA-ALKYGLNHGLTVIDTAEMYG--NGAAESLI 62
Query: 330 KKFSEGLKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHW 482
F R +I++ +K + S+ ++ Q++ AL+ SL+ L +Y+DLYL+HW
Sbjct: 63 GSFLGDYDRANIYLISKFYPSHADKRQMLTALKNSLKRLQTDYLDLYLLHW 113
>UniRef50_A6LZ55 Cluster: 2,5-didehydrogluconate reductase; n=1;
Clostridium beijerinckii NCIMB 8052|Rep:
2,5-didehydrogluconate reductase - Clostridium
beijerinckii NCIMB 8052
Length = 289
Score = 73.7 bits (173), Expect = 7e-12
Identities = 46/122 (37%), Positives = 68/122 (55%)
Frame = +3
Query: 117 DLIVPTLQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKY 296
+LI ++ +G IP V G + + KG+ D E AV A++ GY H DTA Y
Sbjct: 2 NLINKEIKAVNGIKIPQVGFGVYKLN--KGE------DFETAVGEAIKIGYRHFDTAKIY 53
Query: 297 GIEDQVGRALTKKFSEGLKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLI 476
G E +G A+ K + RE FIT+K+WN+ H E A ++ + LN+EY+D+YLI
Sbjct: 54 GNEKDLGLAIEKS---QIPREEFFITSKVWNTDHGYEATKKAFEQTCKKLNVEYLDMYLI 110
Query: 477 HW 482
H+
Sbjct: 111 HF 112
>UniRef50_Q6CEJ0 Cluster: Yarrowia lipolytica chromosome B of strain
CLIB122 of Yarrowia lipolytica; n=1; Yarrowia
lipolytica|Rep: Yarrowia lipolytica chromosome B of
strain CLIB122 of Yarrowia lipolytica - Yarrowia
lipolytica (Candida lipolytica)
Length = 302
Score = 73.7 bits (173), Expect = 7e-12
Identities = 51/156 (32%), Positives = 80/156 (51%), Gaps = 1/156 (0%)
Frame = +3
Query: 120 LIVPTLQLSSGGNIPVVALGTWLG-HRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKY 296
+ VP ++LS+G IP + G+ RP G+ + + AV+ A+ AG+ HIDTA Y
Sbjct: 1 MTVPKVKLSNGLEIPAIGFGSGTKWKRPPGEKEE--RELIDAVVSAINAGHLHIDTAEFY 58
Query: 297 GIEDQVGRALTKKFSEGLKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLI 476
G E Q+G A+ + G+ R+ IF+T+K + I ++ L+ L +Y DL+LI
Sbjct: 59 GTEKQIGEAIKE---SGVPRKDIFLTSKTLFGL-LADDPIESISNQLKTLQTDYFDLFLI 114
Query: 477 HWPIAMFENDTLLDNVDFLDTWRGMIDAKKLGLTKS 584
H P ND + N D W + + GL K+
Sbjct: 115 HVP----PNDDI--NYDLAKAWGVLEQLYEKGLAKA 144
>UniRef50_Q4PHK0 Cluster: Putative uncharacterized protein; n=1;
Ustilago maydis|Rep: Putative uncharacterized protein -
Ustilago maydis (Smut fungus)
Length = 355
Score = 73.7 bits (173), Expect = 7e-12
Identities = 45/141 (31%), Positives = 73/141 (51%), Gaps = 20/141 (14%)
Frame = +3
Query: 132 TLQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQA----------VIYALEAGYTHI- 278
T +L++G IPV+ LGTW G+V + +A + L GY +
Sbjct: 13 TFKLNTGAEIPVIGLGTW--QSAPGEVAKAVESAIKAGYRHIVSMLTSLLTLTLGYVALH 70
Query: 279 ---------DTAYKYGIEDQVGRALTKKFSEGLKRESIFITTKLWNSYHEREQVIPALRK 431
D A+ YG E++VG+ + + G+ R +F+TTK+W +YH + + L +
Sbjct: 71 PLYIPFLAKDAAWIYGNENEVGQGIK---ASGVPRSELFVTTKIWCTYHRQPEA--CLDE 125
Query: 432 SLENLNLEYVDLYLIHWPIAM 494
SL+ L L+YVDL L+HWP+ +
Sbjct: 126 SLQRLGLDYVDLLLVHWPVPL 146
>UniRef50_Q929C8 Cluster: Lin2349 protein; n=12; Listeria|Rep:
Lin2349 protein - Listeria innocua
Length = 294
Score = 73.3 bits (172), Expect = 9e-12
Identities = 36/84 (42%), Positives = 52/84 (61%)
Frame = +3
Query: 240 AVIYALEAGYTHIDTAYKYGIEDQVGRALTKKFSEGLKRESIFITTKLWNSYHEREQVIP 419
AV A+E GY DTA Y E VG+A+ + RE +FI++K+WN ++ +
Sbjct: 36 AVEKAIEVGYRLFDTAAVYNNEAIVGQAI---LDSAVPREELFISSKVWNGDLGYDETLF 92
Query: 420 ALRKSLENLNLEYVDLYLIHWPIA 491
A ++L NL L+Y+DLYLIHWP+A
Sbjct: 93 AFERTLRNLKLDYLDLYLIHWPVA 116
>UniRef50_A4YQ04 Cluster: 2,5-diketo-D-gluconate reductase B; n=15;
Proteobacteria|Rep: 2,5-diketo-D-gluconate reductase B -
Bradyrhizobium sp. (strain ORS278)
Length = 273
Score = 73.3 bits (172), Expect = 9e-12
Identities = 45/114 (39%), Positives = 62/114 (54%)
Frame = +3
Query: 144 SSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQVGRA 323
+ G +P + LGT+ R +G V + AV AL GY HIDTA Y ED +G A
Sbjct: 6 TQGVRLPKLGLGTF---RMQGTVCR------DAVESALALGYRHIDTAEMYANEDAIGAA 56
Query: 324 LTKKFSEGLKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWP 485
L + + RE + +TTK+W + + A SL+ L L++VDLYLIHWP
Sbjct: 57 LA---AAQIAREDLHVTTKVWPENLAPDAIRRAFDTSLKKLRLDFVDLYLIHWP 107
>UniRef50_A1RB46 Cluster: 2,5-diketo-D-gluconate reductase; n=1;
Arthrobacter aurescens TC1|Rep: 2,5-diketo-D-gluconate
reductase - Arthrobacter aurescens (strain TC1)
Length = 273
Score = 73.3 bits (172), Expect = 9e-12
Identities = 55/170 (32%), Positives = 78/170 (45%), Gaps = 1/170 (0%)
Frame = +3
Query: 138 QLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQVG 317
Q S+G +P + LGT G RP D + V +AL+ GY DTA YG E +G
Sbjct: 3 QHSAGTALPAITLGT--GLRPP-------TDVYRLVGWALDMGYRSFDTAALYGTEAAIG 53
Query: 318 RALTKKFSEGLKRESIFITTKL-WNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPIAM 494
RA+ G+ R +FIT K+ N Y R +V A+ +SLE L + D+ + HWP+ M
Sbjct: 54 RAIR---DSGIDRRELFITVKVRGNEYGSRARVHQAIERSLEALGTSFADMVVPHWPLPM 110
Query: 495 FENDTLLDNVDFLDTWRGMIDAKKLGLTKS*ASPTLTRTNPEDHRQRTGE 644
T+ M+DA+ GL + + R TGE
Sbjct: 111 VR--------ALPSTFAQMLDARSEGLVRGVGLSNASSAMVRAVRTETGE 152
>UniRef50_Q927E1 Cluster: Lin2848 protein; n=13; Listeria|Rep:
Lin2848 protein - Listeria innocua
Length = 280
Score = 72.9 bits (171), Expect = 1e-11
Identities = 41/111 (36%), Positives = 60/111 (54%)
Frame = +3
Query: 252 ALEAGYTHIDTAYKYGIEDQVGRALTKKFSEGLKRESIFITTKLWNSYHEREQVIPALRK 431
A++ GY DTA Y E ++G S GLKR+ F+TTK+WN+ ++ + A K
Sbjct: 40 AVDVGYRLFDTASFYHNEKELGDFFA---SSGLKRDEFFVTTKMWNTEQGYDETLRAFEK 96
Query: 432 SLENLNLEYVDLYLIHWPIAMFENDTLLDNVDFLDTWRGMIDAKKLGLTKS 584
S + L L+ VDLYL+HWP + DT F +TWR + GL ++
Sbjct: 97 SQKKLQLDQVDLYLVHWP----KQDT------FFETWRAVEKLYDEGLVRA 137
>UniRef50_Q54NR2 Cluster: Aldo-keto reductase; n=3; Dictyostelium
discoideum AX4|Rep: Aldo-keto reductase - Dictyostelium
discoideum AX4
Length = 305
Score = 72.5 bits (170), Expect = 2e-11
Identities = 39/117 (33%), Positives = 60/117 (51%), Gaps = 8/117 (6%)
Frame = +3
Query: 225 NDTEQAVIYALEAGYTHIDTAYKYGIEDQVGRALTKKFSEG-------LKRESIFITTKL 383
ND E + LE GY IDTA Y E+++G+ L + ++ +KRE +FIT+K
Sbjct: 38 NDIENIIKVGLENGYRRIDTASMYNNEERIGKVLNEMVTKNDGLDGKKIKREDLFITSKC 97
Query: 384 WNSYHEREQVIPALRKSLENLNLEYVDLYLIHWP-IAMFENDTLLDNVDFLDTWRGM 551
E + A SL+ L L+Y+D YLIHWP + + +++ TWR +
Sbjct: 98 SFMEQGYENALKAFESSLKKLQLDYLDCYLIHWPGVKGLDGSDSGNSIQRAQTWRAL 154
>UniRef50_A7D6Q0 Cluster: Aldo/keto reductase; n=1; Halorubrum
lacusprofundi ATCC 49239|Rep: Aldo/keto reductase -
Halorubrum lacusprofundi ATCC 49239
Length = 309
Score = 72.5 bits (170), Expect = 2e-11
Identities = 43/120 (35%), Positives = 62/120 (51%)
Frame = +3
Query: 126 VPTLQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIE 305
+PT L SG +P + LGT+ + +V AL +GYTHIDTA Y E
Sbjct: 34 IPTQTLPSGDTLPALGLGTY---------ALDDDQIADSVRAALSSGYTHIDTAEGYHNE 84
Query: 306 DQVGRALTKKFSEGLKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWP 485
+ +G L + R+ +F+T+K+ E +I + SLE L +Y+DLYLIHWP
Sbjct: 85 EAIGEVLAE-----YDRDDVFLTSKVLAKNLGYESLIQSCEASLERLETDYLDLYLIHWP 139
>UniRef50_A3VRL4 Cluster: Putative uncharacterized protein; n=1;
Parvularcula bermudensis HTCC2503|Rep: Putative
uncharacterized protein - Parvularcula bermudensis
HTCC2503
Length = 278
Score = 72.1 bits (169), Expect = 2e-11
Identities = 40/110 (36%), Positives = 63/110 (57%)
Frame = +3
Query: 159 IPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQVGRALTKKF 338
IP + GTW + +G+ + + T A+E GY HID A Y E +VG +
Sbjct: 11 IPRLGFGTW---QLEGEDARTSTRT------AIETGYRHIDGAAIYKNEKKVGEGIK--- 58
Query: 339 SEGLKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPI 488
G+ R+ +F+TTK+WN ++ + A+ +SL+ L L+YV+L L+HWPI
Sbjct: 59 DSGIPRDELFVTTKIWNEDIQKGRHSEAVDESLDRLGLDYVNLILLHWPI 108
>UniRef50_Q76L36 Cluster: Conjugated polyketone reductase C2; n=1;
Candida parapsilosis|Rep: Conjugated polyketone
reductase C2 - Candida parapsilosis (Yeast)
Length = 307
Score = 72.1 bits (169), Expect = 2e-11
Identities = 48/159 (30%), Positives = 77/159 (48%), Gaps = 4/159 (2%)
Frame = +3
Query: 108 TSADLIVPTLQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTA 287
T ++L+ T + SG I + ALGT + + V+ + ++ L+ G+ HIDTA
Sbjct: 2 TQSNLLPKTFRTKSGKEISI-ALGTGTKWKQAQTINDVSTELVDNILLGLKLGFRHIDTA 60
Query: 288 YKYGIEDQVGRALTKKFSEGLKRESIFITTKL---WNSYHE-REQVIPALRKSLENLNLE 455
Y + +VG AL + + RE I++TTK W S + ++ K+L L ++
Sbjct: 61 EAYNTQKEVGEALKR---TDVPREDIWVTTKYSPGWGSIKAYSKSPSDSIDKALAQLGVD 117
Query: 456 YVDLYLIHWPIAMFENDTLLDNVDFLDTWRGMIDAKKLG 572
YVDL+LIH P E W +++AKK G
Sbjct: 118 YVDLFLIHSPFFTTEQ---THGYTLEQAWEALVEAKKAG 153
>UniRef50_A6VNW9 Cluster: Aldo/keto reductase precursor; n=1;
Actinobacillus succinogenes 130Z|Rep: Aldo/keto
reductase precursor - Actinobacillus succinogenes 130Z
Length = 315
Score = 71.7 bits (168), Expect = 3e-11
Identities = 46/126 (36%), Positives = 70/126 (55%)
Frame = +3
Query: 132 TLQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQ 311
T++L++G +P++ +G W TE++V AL+AGY IDTA Y E
Sbjct: 44 TVKLNNGIEMPIIGIGVW---------TLTPEQTEKSVGEALKAGYRLIDTARMYRNEQA 94
Query: 312 VGRALTKKFSEGLKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPIA 491
VGRA+ G+ RE IFITTK++ S + A+ + L L+ +Y+DL L+H+P
Sbjct: 95 VGRAVR---DSGIPREEIFITTKIYGS-GDYANAEAAINERLRLLDTDYIDLLLLHYP-- 148
Query: 492 MFENDT 509
+NDT
Sbjct: 149 -DQNDT 153
>UniRef50_Q17G72 Cluster: Aldo-keto reductase; n=9;
Endopterygota|Rep: Aldo-keto reductase - Aedes aegypti
(Yellowfever mosquito)
Length = 316
Score = 71.7 bits (168), Expect = 3e-11
Identities = 51/161 (31%), Positives = 75/161 (46%), Gaps = 11/161 (6%)
Frame = +3
Query: 135 LQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQV 314
+ +G +P + GTW + E+A+ ALEAGY HIDTA Y E +
Sbjct: 7 ITFENGTTMPALGFGTWRAS---------DEEVEKALNEALEAGYRHIDTAPVYLNEKTI 57
Query: 315 GRALTKKFSEG-LKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPIA 491
G+ L + G + R+ +FI TKL V L+ SL++L LEYVDLY +H P
Sbjct: 58 GKVLKEWMDAGKVTRDELFIVTKLPPHGTRASTVEKFLKNSLDDLQLEYVDLYHVHVPFT 117
Query: 492 MFEND----------TLLDNVDFLDTWRGMIDAKKLGLTKS 584
+ E D L D + W+ M + + GL ++
Sbjct: 118 VPEVDGPFLVEDGLIVLETTTDHVALWKAMEEVYEAGLARN 158
>UniRef50_Q03X85 Cluster: Aldo/keto reductase of diketogulonate
reductase family; n=1; Leuconostoc mesenteroides subsp.
mesenteroides ATCC 8293|Rep: Aldo/keto reductase of
diketogulonate reductase family - Leuconostoc
mesenteroides subsp. mesenteroides (strain ATCC 8293
/NCDO 523)
Length = 288
Score = 71.3 bits (167), Expect = 4e-11
Identities = 36/87 (41%), Positives = 52/87 (59%), Gaps = 1/87 (1%)
Frame = +3
Query: 228 DTEQAVIYALEAGYTHIDTAYKYGIEDQVGRALTKKFSEGL-KRESIFITTKLWNSYHER 404
+T+QAV+ A+ AGY IDTA YG E + G+ + + + + RE +F+TTKLW S
Sbjct: 26 ETKQAVVDAINAGYRSIDTARVYGNEAETGQGVNEAIANAVVAREELFLTTKLWLSEFSY 85
Query: 405 EQVIPALRKSLENLNLEYVDLYLIHWP 485
E A+ SL+ L +Y DL L+H P
Sbjct: 86 EAAKGAIDDSLKKLGTDYADLILLHQP 112
>UniRef50_Q5K8C5 Cluster: Aldo-keto reductase, putative; n=1;
Filobasidiella neoformans|Rep: Aldo-keto reductase,
putative - Cryptococcus neoformans (Filobasidiella
neoformans)
Length = 303
Score = 71.3 bits (167), Expect = 4e-11
Identities = 47/120 (39%), Positives = 64/120 (53%), Gaps = 1/120 (0%)
Frame = +3
Query: 228 DTEQAVIYALEAGYTHIDTAYKYGIEDQVGRALTKKF-SEGLKRESIFITTKLWNSYHER 404
+T V +ALEAGY H+DTA Y E G+A+ + G RE IF+T+KL N+
Sbjct: 55 ETYDCVKWALEAGYRHVDTAEWYENEAPCGKAIADFLKATGTSREEIFLTSKLKNN-SSY 113
Query: 405 EQVIPALRKSLENLNLEYVDLYLIHWPIAMFENDTLLDNVDFLDTWRGMIDAKKLGLTKS 584
EQ L+ SL+ +EY DLYL+H I + NV W+ + DA+ GL KS
Sbjct: 114 EQAFVDLKGSLKRSGVEYFDLYLMHSAIG---GPVIRKNV-----WKALCDAQSQGLVKS 165
>UniRef50_Q5FK99 Cluster: Oxidoreductase aldo-keto reductase family;
n=5; Lactobacillus|Rep: Oxidoreductase aldo-keto
reductase family - Lactobacillus acidophilus
Length = 289
Score = 70.5 bits (165), Expect = 6e-11
Identities = 50/155 (32%), Positives = 75/155 (48%), Gaps = 2/155 (1%)
Frame = +3
Query: 126 VPTLQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTE--QAVIYALEAGYTHIDTAYKYG 299
+P ++L+ G IP + G V Q++N E +AV A+ GY IDTA Y
Sbjct: 4 IPKIKLNDGNEIPQLGFG----------VFQISNHDEAVKAVESAISNGYRLIDTAEAYN 53
Query: 300 IEDQVGRALTKKFSEGLKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIH 479
+ VG A+ + + R+ IF+TTKLW S E+ A+ + L+ L +Y+D+ L+H
Sbjct: 54 NQTAVGEAIK---NSDVNRDDIFLTTKLWVSNFTYEKASKAIDEDLKELGTDYIDMMLLH 110
Query: 480 WPIAMFENDTLLDNVDFLDTWRGMIDAKKLGLTKS 584
D WR + DA+K G TKS
Sbjct: 111 QAYG-----------DVAGAWRALEDAQKAGKTKS 134
>UniRef50_A7BES9 Cluster: Putative uncharacterized protein; n=1;
Actinomyces odontolyticus ATCC 17982|Rep: Putative
uncharacterized protein - Actinomyces odontolyticus ATCC
17982
Length = 282
Score = 70.5 bits (165), Expect = 6e-11
Identities = 45/117 (38%), Positives = 64/117 (54%)
Frame = +3
Query: 135 LQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQV 314
+ L++G IP V LGT+L +D + AV YAL+ YT IDTA Y E V
Sbjct: 4 ITLNNGITIPQVGLGTYLLE---------PDDAQSAVTYALDNDYTLIDTANVYVNERAV 54
Query: 315 GRALTKKFSEGLKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWP 485
GR + + R+ IF+ TKLW S+ ER A+ ++LE L +Y+DL ++H P
Sbjct: 55 GRGMR---ASSKARDEIFLETKLWPSFFERAS---AVEETLERLGTDYIDLMILHQP 105
>UniRef50_Q2U219 Cluster: Aldo/keto reductase family proteins; n=6;
Pezizomycotina|Rep: Aldo/keto reductase family proteins
- Aspergillus oryzae
Length = 294
Score = 70.5 bits (165), Expect = 6e-11
Identities = 40/119 (33%), Positives = 65/119 (54%)
Frame = +3
Query: 129 PTLQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIED 308
P ++L+ +IP++ GT + V + +A+ A+ GY H+D A YG E
Sbjct: 10 PRVKLNDNVSIPILGYGTGTAWYKQAGDDSVNRELVEAIKTAIRLGYRHLDGAEVYGTEA 69
Query: 309 QVGRALTKKFSEGLKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWP 485
++G A+ + G+ RE +F+TTK+ + + + A+ +SL L L YVDLYLIH P
Sbjct: 70 ELGVAIKE---SGIPREELFVTTKVITNIAD---IPSAIDQSLRKLQLNYVDLYLIHSP 122
>UniRef50_Q5V398 Cluster: Oxidoreductase aldo/keto reductase family;
n=1; Haloarcula marismortui|Rep: Oxidoreductase
aldo/keto reductase family - Haloarcula marismortui
(Halobacterium marismortui)
Length = 302
Score = 70.5 bits (165), Expect = 6e-11
Identities = 42/91 (46%), Positives = 55/91 (60%), Gaps = 4/91 (4%)
Frame = +3
Query: 240 AVIYALEAGYTHIDTAYKYGIEDQVGRALTKKFSEGLKRESIFITTKL--WNSYHEREQV 413
AV AL+ GYTHIDTA Y E VGRA+ + + RE IF+TTK+ + E E++
Sbjct: 38 AVKNALDCGYTHIDTAMAYENEAAVGRAIEQ---SSVDREDIFLTTKIKGYPEMVEYERL 94
Query: 414 IPALRKSLENLNLEYVDLYLIHW--PIAMFE 500
I A + LE L EY+DL L+HW P+A E
Sbjct: 95 IEAAKGCLERLGTEYLDLLLVHWWNPLADME 125
>UniRef50_Q5UYI9 Cluster: Oxidoreductase; n=1; Haloarcula
marismortui|Rep: Oxidoreductase - Haloarcula marismortui
(Halobacterium marismortui)
Length = 264
Score = 70.5 bits (165), Expect = 6e-11
Identities = 36/90 (40%), Positives = 51/90 (56%), Gaps = 1/90 (1%)
Frame = +3
Query: 219 VTNDTEQAVIYA-LEAGYTHIDTAYKYGIEDQVGRALTKKFSEGLKRESIFITTKLWNSY 395
+ DT Q + A L GY H+DTA Y E ++G AL RE +F+T+K+ +
Sbjct: 9 IDGDTVQKSVRAGLNVGYAHVDTAEGYKNESEIGEALAD-----YDREDVFLTSKVLPKH 63
Query: 396 HEREQVIPALRKSLENLNLEYVDLYLIHWP 485
+ E VI A SL+ L +Y+DLYL+HWP
Sbjct: 64 LDYESVIEACEASLDRLGTDYLDLYLVHWP 93
>UniRef50_Q5V6N9 Cluster: Alcohol dehydrogenase; n=2;
Halobacteriaceae|Rep: Alcohol dehydrogenase - Haloarcula
marismortui (Halobacterium marismortui)
Length = 667
Score = 70.1 bits (164), Expect = 8e-11
Identities = 33/95 (34%), Positives = 54/95 (56%)
Frame = +3
Query: 228 DTEQAVIYALEAGYTHIDTAYKYGIEDQVGRALTKKFSEGLKRESIFITTKLWNSYHERE 407
D ++ AL+AGY +D+A YG E ++GR L + +R +FI K+W + H R+
Sbjct: 395 DRADSIAAALDAGYRLLDSAELYGNEHRIGRILAAPGAPDRRR--VFILGKVWRTNHRRK 452
Query: 408 QVIPALRKSLENLNLEYVDLYLIHWPIAMFENDTL 512
++ A R SL+ L ++ D Y +HWP A+ +L
Sbjct: 453 HMLTACRSSLDELGIDAFDCYALHWPEALAHRGSL 487
>UniRef50_UPI00006CA3CB Cluster: oxidoreductase, aldo/keto reductase
family protein; n=3; Tetrahymena thermophila SB210|Rep:
oxidoreductase, aldo/keto reductase family protein -
Tetrahymena thermophila SB210
Length = 299
Score = 69.7 bits (163), Expect = 1e-10
Identities = 51/159 (32%), Positives = 75/159 (47%), Gaps = 2/159 (1%)
Frame = +3
Query: 111 SADLIVPTLQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAY 290
S+ I + LS+G +P LG+ VQ + + AL+ GY HIDTA
Sbjct: 2 SSQEIQKVITLSNGQKMPAFGLGS--------SRVQSVEEVTNLIRKALDVGYRHIDTAQ 53
Query: 291 KYGIEDQVGRALTKKFSEG-LKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDL 467
Y E +G AL F EG KRE IF+ TK + + + +++ L+ L ++YVDL
Sbjct: 54 MYENEQFIGAALKTIFGEGKYKREDIFLVTK--QASIKGVSCLEIMKEQLQKLQVDYVDL 111
Query: 468 YLIHWPIAMFEND-TLLDNVDFLDTWRGMIDAKKLGLTK 581
LIH P+A +D ++ W + LGL K
Sbjct: 112 LLIHVPLAAPSDDYQQWNHKPVHQIWAEFEEIHSLGLAK 150
>UniRef50_Q11B35 Cluster: Aldo/keto reductase; n=1; Mesorhizobium
sp. BNC1|Rep: Aldo/keto reductase - Mesorhizobium sp.
(strain BNC1)
Length = 253
Score = 69.7 bits (163), Expect = 1e-10
Identities = 53/182 (29%), Positives = 86/182 (47%), Gaps = 1/182 (0%)
Frame = +3
Query: 159 IPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQVGRALTKKF 338
+P++ LGTW Q+T++T + V A + GY +DT+ YG + +G A+
Sbjct: 1 MPILGLGTW----------QLTHETARTVRAAFDLGYRMVDTSGDYGTQSAIGEAIR--- 47
Query: 339 SEGLKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPIAMFENDTLLD 518
+ GL R+ I++ TK+ E E A + +L L L+Y DL LIH P + L
Sbjct: 48 ASGLDRDDIYLVTKV----EETEDAYNATQANLRELGLDYADLILIHRPPRHGAGEEL-- 101
Query: 519 NVDFLDTWRGMIDAKKLGLTKS*ASPTLTRTNPEDHRQRTGEXSAL-QIELTSTAHKFHL 695
WR +I A++ GLT+ + E+ TGE + Q+E + H L
Sbjct: 102 -------WRALIRAREDGLTRDIGVSNYSIELIEELVDATGEIPVVNQVEWSPFGHDLEL 154
Query: 696 RN 701
++
Sbjct: 155 KH 156
>UniRef50_Q7VHE1 Cluster: Putative uncharacterized protein; n=1;
Helicobacter hepaticus|Rep: Putative uncharacterized
protein - Helicobacter hepaticus
Length = 270
Score = 69.3 bits (162), Expect = 1e-10
Identities = 44/118 (37%), Positives = 64/118 (54%)
Frame = +3
Query: 132 TLQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQ 311
TL L++G +P++ LGT+ GK Q +A+ A+E GY D+A Y E +
Sbjct: 3 TLTLNNGVKMPILGLGTY---SLTGKAGQ------KAMSEAIEVGYRLFDSAQMYNNEAE 53
Query: 312 VGRALTKKFSEGLKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWP 485
+G A+ G+KRE FI TKL S E + ++ KSL+ L L+Y+D LIH P
Sbjct: 54 LGAAINAAVKGGIKREEFFIQTKLLESSSE-DLAKKSIEKSLKTLGLDYIDSLLIHMP 110
>UniRef50_Q5FT75 Cluster: Putative 2,5-diketo-D-gluconic acid
reductase; n=1; Gluconobacter oxydans|Rep: Putative
2,5-diketo-D-gluconic acid reductase - Gluconobacter
oxydans (Gluconobacter suboxydans)
Length = 279
Score = 69.3 bits (162), Expect = 1e-10
Identities = 51/179 (28%), Positives = 77/179 (43%), Gaps = 1/179 (0%)
Frame = +3
Query: 135 LQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQV 314
+ G +P + LG W P + +V + A++ GY +DTA Y E+ V
Sbjct: 14 ISFHDGHTMPQIGLGVW--ETPPDETAEVVKE-------AVKLGYRSVDTARLYKNEEGV 64
Query: 315 GRALTKKFSEGLKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPIAM 494
G+ L IF+TTKLWN + + A +S L +DLYLIHWP+
Sbjct: 65 GKGLED-------HPEIFLTTKLWNDEQGYDSTLRAYEESARLLRRPVLDLYLIHWPMPA 117
Query: 495 FENDTLLDNVDFLDTWRGMIDAKKLGLTKS*ASPTLTRTNPEDHRQRTGEXSAL-QIEL 668
+++TW+ +++ KK G KS + E TG + QIEL
Sbjct: 118 --------QGQYVETWKALVELKKSGRVKSIGVSNFESEHLERIMDATGVVPVVNQIEL 168
>UniRef50_Q11BF8 Cluster: Aldo/keto reductase; n=12; Bacteria|Rep:
Aldo/keto reductase - Mesorhizobium sp. (strain BNC1)
Length = 308
Score = 68.9 bits (161), Expect = 2e-10
Identities = 36/96 (37%), Positives = 55/96 (57%)
Frame = +3
Query: 225 NDTEQAVIYALEAGYTHIDTAYKYGIEDQVGRALTKKFSEGLKRESIFITTKLWNSYHER 404
++T AV AL GY HIDTA YG E +VG + + G+ R+ +FI TK+W S +
Sbjct: 42 DETTAAVEEALRLGYRHIDTAAAYGNEREVGEGIRRA---GIARDEVFIETKIWISDYGY 98
Query: 405 EQVIPALRKSLENLNLEYVDLYLIHWPIAMFENDTL 512
++ + A KS L ++ +DL L+H P+ + TL
Sbjct: 99 DETLHAFDKSAGKLGVDQIDLLLLHQPLPSAFDRTL 134
>UniRef50_A2RMU6 Cluster: Oxidoreductase, aldo/keto reductase
family; n=3; Lactococcus lactis|Rep: Oxidoreductase,
aldo/keto reductase family - Lactococcus lactis subsp.
cremoris (strain MG1363)
Length = 281
Score = 68.9 bits (161), Expect = 2e-10
Identities = 46/119 (38%), Positives = 64/119 (53%)
Frame = +3
Query: 141 LSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQVGR 320
L+ G IP LG + P+G+ TE AV AL GY HIDTA+ Y E VGR
Sbjct: 7 LNDGNIIPQFGLGVY--QIPEGEA------TENAVKEALRLGYRHIDTAHAYQNERSVGR 58
Query: 321 ALTKKFSEGLKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPIAMF 497
A+ S G+ I+IT+KLW S + + A+ + LE LNL+ +DL L+H + +
Sbjct: 59 AI---HSSGIPISEIWITSKLWPS--DYDDASQAIERMLELLNLKQIDLLLLHQQVGNY 112
>UniRef50_Q4JCC1 Cluster: 2,5-diketo-D-gluconic acid reductase A;
n=3; Archaea|Rep: 2,5-diketo-D-gluconic acid reductase A
- Sulfolobus acidocaldarius
Length = 267
Score = 68.9 bits (161), Expect = 2e-10
Identities = 36/86 (41%), Positives = 52/86 (60%), Gaps = 3/86 (3%)
Frame = +3
Query: 237 QAVIYALEAGYTHIDTAYKYG---IEDQVGRALTKKFSEGLKRESIFITTKLWNSYHERE 407
+A+ Y + G IDTA YG E+ VG+A+ RES+FITTK+W ++ + +
Sbjct: 35 EAIKYTINKGINLIDTAEMYGGGHTEEIVGKAVAD-----FDRESLFITTKVWPNHLKYD 89
Query: 408 QVIPALRKSLENLNLEYVDLYLIHWP 485
I + SL+ LN +Y+DLYLIHWP
Sbjct: 90 DTIKSALASLKRLNTKYIDLYLIHWP 115
>UniRef50_A3LWP0 Cluster: Aldo/keto reductase; n=7;
Saccharomycetales|Rep: Aldo/keto reductase - Pichia
stipitis (Yeast)
Length = 323
Score = 68.5 bits (160), Expect = 3e-10
Identities = 45/135 (33%), Positives = 67/135 (49%), Gaps = 5/135 (3%)
Frame = +3
Query: 183 WLGH-RPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQVGRALTKKFSEGLKRE 359
WL RP+ + +T + +++ ALE GY HIDTA Y +V A+ K G+ RE
Sbjct: 35 WLKKGRPEEEQNTLTTELVDSILLALENGYNHIDTAEVYTTHPEVAAAVKK---SGIARE 91
Query: 360 SIFITTKLWNSYHEREQVIPA----LRKSLENLNLEYVDLYLIHWPIAMFENDTLLDNVD 527
+FITTK + + + ++L+ L +YVDL+LIH P F + +
Sbjct: 92 DLFITTKYTPGFRTFPAISSGPTEFIDRALKELETDYVDLFLIHSP---FFEEKVSRGQT 148
Query: 528 FLDTWRGMIDAKKLG 572
W +IDAKK G
Sbjct: 149 LESAWAEVIDAKKAG 163
>UniRef50_A3JU52 Cluster: 2,5-diketo-D-gluconic acid reductase A;
n=1; Rhodobacterales bacterium HTCC2150|Rep:
2,5-diketo-D-gluconic acid reductase A - Rhodobacterales
bacterium HTCC2150
Length = 334
Score = 68.1 bits (159), Expect = 3e-10
Identities = 52/160 (32%), Positives = 78/160 (48%), Gaps = 9/160 (5%)
Frame = +3
Query: 132 TLQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYA-LEAGYTHIDTAYKYGIED 308
T L++ IP V GT+L ++ND ++ I A ++AGY HIDTA Y E
Sbjct: 39 TFTLNTTTTIPAVGFGTYL----------ISNDDAKSTISAAIQAGYRHIDTASGYQNEK 88
Query: 309 QVGRALTKKF-SEGLKRESIFITTKLW-------NSYHEREQVIPALRKSLENLNLEYVD 464
VG + S G+ R+ +F+T KLW ++ + Q + SL L L+YVD
Sbjct: 89 TVGAGIKAGLQSAGITRKDLFVTAKLWPGNPAWGDAPKTKAQTLDECDASLARLGLDYVD 148
Query: 465 LYLIHWPIAMFENDTLLDNVDFLDTWRGMIDAKKLGLTKS 584
LYLIH P + D L+ WR +++ + G +S
Sbjct: 149 LYLIHAP---YGGDMRLEQ------WRALLELQANGKARS 179
>UniRef50_Q97U17 Cluster: Oxidoreductase, aldo/keto reductase
family; n=2; Sulfolobaceae|Rep: Oxidoreductase,
aldo/keto reductase family - Sulfolobus solfataricus
Length = 265
Score = 68.1 bits (159), Expect = 3e-10
Identities = 34/82 (41%), Positives = 51/82 (62%), Gaps = 3/82 (3%)
Frame = +3
Query: 249 YALEAGYTHIDTAYKYG---IEDQVGRALTKKFSEGLKRESIFITTKLWNSYHEREQVIP 419
Y + G IDTA YG E+ VG+A+ E R+ IFI TK+W+++ + + +I
Sbjct: 39 YVISKGINVIDTAEMYGGGHSEELVGKAI-----ENFDRDKIFIITKVWSNHLKYDDLIR 93
Query: 420 ALRKSLENLNLEYVDLYLIHWP 485
+ + SL+ LN +Y+DLYLIHWP
Sbjct: 94 SAKNSLKRLNAKYIDLYLIHWP 115
>UniRef50_Q14LA8 Cluster: Putative aldo/keto reductase
oxidoreductase protein; n=1; Spiroplasma citri|Rep:
Putative aldo/keto reductase oxidoreductase protein -
Spiroplasma citri
Length = 263
Score = 67.7 bits (158), Expect = 4e-10
Identities = 38/85 (44%), Positives = 51/85 (60%), Gaps = 1/85 (1%)
Frame = +3
Query: 234 EQAVIYALEAGYTHIDTAYKYGIEDQVGRALTKKF-SEGLKRESIFITTKLWNSYHEREQ 410
E+A+I AL+ GY IDTA Y E+ VGRA+ K S +RE I I TK+W E
Sbjct: 18 EEAIINALQNGYKIIDTAKVYQNEEIVGRAIKKYLNSNNQRREDIIIETKIWCDDVEAGN 77
Query: 411 VIPALRKSLENLNLEYVDLYLIHWP 485
A+ +SL+ LN+ Y+D+ LIH P
Sbjct: 78 TTNAVLESLKRLNVTYLDIVLIHRP 102
>UniRef50_Q6CWB9 Cluster: Similarities with sp|Q12458 Saccharomyces
cerevisiae YDR368w YPR1; n=1; Kluyveromyces lactis|Rep:
Similarities with sp|Q12458 Saccharomyces cerevisiae
YDR368w YPR1 - Kluyveromyces lactis (Yeast) (Candida
sphaerica)
Length = 127
Score = 67.7 bits (158), Expect = 4e-10
Identities = 32/67 (47%), Positives = 44/67 (65%)
Frame = +3
Query: 294 YGIEDQVGRALTKKFSEGLKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYL 473
YG E VG+ + G+ RE IF+TTKLWN+ ++ AL +SLE L L+YVDL+L
Sbjct: 2 YGNETAVGKGIR---DSGIPREEIFVTTKLWNT--QQRDPASALNESLERLGLDYVDLFL 56
Query: 474 IHWPIAM 494
IHWP+ +
Sbjct: 57 IHWPVPL 63
>UniRef50_Q5FLI5 Cluster: Aldehyde reductase; n=2; Bacteria|Rep:
Aldehyde reductase - Lactobacillus acidophilus
Length = 278
Score = 67.3 bits (157), Expect = 6e-10
Identities = 37/84 (44%), Positives = 50/84 (59%)
Frame = +3
Query: 234 EQAVIYALEAGYTHIDTAYKYGIEDQVGRALTKKFSEGLKRESIFITTKLWNSYHEREQV 413
+Q V LE GY +DTA YG E VG A+ K S + RE IFIT+K+W + +
Sbjct: 30 QQVVEDGLEVGYRLVDTAQIYGNEQAVGDAI--KHSN-VPREDIFITSKIWVDDYGYDNT 86
Query: 414 IPALRKSLENLNLEYVDLYLIHWP 485
+ A S++ L L+Y+DLYLIH P
Sbjct: 87 LKAFDDSMKKLQLDYIDLYLIHKP 110
>UniRef50_A7SGW6 Cluster: Predicted protein; n=1; Nematostella
vectensis|Rep: Predicted protein - Nematostella
vectensis
Length = 264
Score = 67.3 bits (157), Expect = 6e-10
Identities = 36/92 (39%), Positives = 54/92 (58%)
Frame = +3
Query: 210 VVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQVGRALTKKFSEGLKRESIFITTKLWN 389
V ++ E ++AL+ GY +DTA Y E +VG A+ K GLKRE I++TTKL
Sbjct: 28 VFRLETGCEDVCLFALKNGYRMLDTADIYQNEKEVGSAVRKS---GLKREDIYVTTKLKP 84
Query: 390 SYHEREQVIPALRKSLENLNLEYVDLYLIHWP 485
S + ++S++ L++ YVDL+LIH P
Sbjct: 85 SEEGHSNALKYAKESIKKLDIGYVDLFLIHTP 116
>UniRef50_A4IJ00 Cluster: LOC548351 protein; n=1; Xenopus
tropicalis|Rep: LOC548351 protein - Xenopus tropicalis
(Western clawed frog) (Silurana tropicalis)
Length = 248
Score = 66.9 bits (156), Expect = 8e-10
Identities = 42/115 (36%), Positives = 65/115 (56%), Gaps = 1/115 (0%)
Frame = +3
Query: 126 VPTLQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEA-GYTHIDTAYKYGI 302
+PT+ L+SG +IP++ LG + H V A++YAL G HIDTA +YG
Sbjct: 6 IPTVPLASGKHIPLLGLG--MSH--------VGGYCHNALLYALTTCGIRHIDTAKRYGN 55
Query: 303 EDQVGRALTKKFSEGLKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDL 467
E VG+A+ + G+KRE +++TTKLW + E I A S + L ++Y+ +
Sbjct: 56 EVMVGKAICES---GVKREELWLTTKLWPGDYGYENAIQACLDSCKRLGVDYLGI 107
>UniRef50_A3T261 Cluster: Putative uncharacterized protein; n=1;
Sulfitobacter sp. NAS-14.1|Rep: Putative uncharacterized
protein - Sulfitobacter sp. NAS-14.1
Length = 274
Score = 66.9 bits (156), Expect = 8e-10
Identities = 36/91 (39%), Positives = 50/91 (54%), Gaps = 1/91 (1%)
Frame = +3
Query: 216 QVTNDT-EQAVIYALEAGYTHIDTAYKYGIEDQVGRALTKKFSEGLKRESIFITTKLWNS 392
Q+ DT V AL G+ HIDTA Y E+QVG L + ++R+ +F+TTK+
Sbjct: 20 QLEQDTVADMVAAALSEGFRHIDTAQAYQNEEQVGEGLRRA---DVRRDEVFLTTKILPE 76
Query: 393 YHEREQVIPALRKSLENLNLEYVDLYLIHWP 485
+ E A SL+ L +YVDL L+HWP
Sbjct: 77 HFSPEAFTAAADASLKRLGTDYVDLLLLHWP 107
>UniRef50_Q75E75 Cluster: ABL209Cp; n=1; Eremothecium gossypii|Rep:
ABL209Cp - Ashbya gossypii (Yeast) (Eremothecium
gossypii)
Length = 310
Score = 66.9 bits (156), Expect = 8e-10
Identities = 53/153 (34%), Positives = 73/153 (47%), Gaps = 4/153 (2%)
Frame = +3
Query: 138 QLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIY-ALEAGYTHIDTAYKYGIEDQV 314
+LS G IP V LG V QV+ T Q ++Y ALE GY D+A Y ED V
Sbjct: 14 RLSDGTQIPSVGLG----------VYQVSEQTVQDLVYEALEVGYRLFDSAQAYHNEDGV 63
Query: 315 GRALTK--KFSEGLKRESIFITTKLWNSYHEREQVIPALRKSLENLN-LEYVDLYLIHWP 485
R + K + G +RE ++ TTK+ H E +L KSL L Y+DL L+H P
Sbjct: 64 ARGIAAWLKHAPGRRREDVYFTTKINTQNHGYEATKKSLEKSLHAAGPLGYIDLVLVHAP 123
Query: 486 IAMFENDTLLDNVDFLDTWRGMIDAKKLGLTKS 584
++ D L TW+ + +A G +S
Sbjct: 124 MS--------DRTRRLGTWQALEEAVVEGQVRS 148
>UniRef50_Q97UV9 Cluster: Oxidoreductase; n=1; Sulfolobus
solfataricus|Rep: Oxidoreductase - Sulfolobus
solfataricus
Length = 304
Score = 66.9 bits (156), Expect = 8e-10
Identities = 42/112 (37%), Positives = 60/112 (53%), Gaps = 3/112 (2%)
Frame = +3
Query: 159 IPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYG---IEDQVGRALT 329
I + LG+W P + N+ +A+ A+E G IDTA YG E +GRA++
Sbjct: 13 ISPLILGSWEFGTPS---IIDENNAIKAIQRAIELGINAIDTAESYGNGLSETIIGRAIS 69
Query: 330 KKFSEGLKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWP 485
K KRE +FI TK+ + + V+ A SL+ LN Y+DLYL+HWP
Sbjct: 70 K-----FKREDLFIITKVSIDHLRYDDVLKASEGSLKRLNTSYIDLYLVHWP 116
>UniRef50_Q8EUH6 Cluster: Oxidoreductase; n=1; Mycoplasma
penetrans|Rep: Oxidoreductase - Mycoplasma penetrans
Length = 285
Score = 66.5 bits (155), Expect = 1e-09
Identities = 41/118 (34%), Positives = 69/118 (58%), Gaps = 1/118 (0%)
Frame = +3
Query: 135 LQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEA-GYTHIDTAYKYGIEDQ 311
++L++G ++P++ LG + + +G+ + E +I A++ GY IDTA Y E+
Sbjct: 4 IKLANGLHMPIIGLGVY---KAEGE------NCENTIIKAIDDYGYRMIDTAQVYFNEEF 54
Query: 312 VGRALTKKFSEGLKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWP 485
VG A+ + +KRE IFITTK+W S + + ++ KSL+ L Y+DL L+H P
Sbjct: 55 VGNAIKQT---KIKREDIFITTKVWISNYGYNNTMYSISKSLKKLQTNYIDLVLLHQP 109
>UniRef50_Q16CS5 Cluster: 2,5-diketo-D-gluconic acid reductase B,
putative; n=3; Bacteria|Rep: 2,5-diketo-D-gluconic acid
reductase B, putative - Roseobacter denitrificans
(strain ATCC 33942 / OCh 114) (Erythrobactersp. (strain
OCh 114)) (Roseobacter denitrificans)
Length = 272
Score = 66.5 bits (155), Expect = 1e-09
Identities = 32/87 (36%), Positives = 53/87 (60%)
Frame = +3
Query: 240 AVIYALEAGYTHIDTAYKYGIEDQVGRALTKKFSEGLKRESIFITTKLWNSYHEREQVIP 419
A++ A E GY DTA Y E + G AL + G+ R+++ +TTK+ N ++ + +
Sbjct: 26 AILTAAEVGYRAFDTAQMYRNEAETGAALKET---GIPRDTLCVTTKVENDNYDESKFLA 82
Query: 420 ALRKSLENLNLEYVDLYLIHWPIAMFE 500
++ SL+ L L+YVD+ L+HWP A F+
Sbjct: 83 SVEASLKALQLDYVDVLLLHWPPADFQ 109
>UniRef50_A6PR52 Cluster: Aldo/keto reductase; n=1; Victivallis
vadensis ATCC BAA-548|Rep: Aldo/keto reductase -
Victivallis vadensis ATCC BAA-548
Length = 287
Score = 66.5 bits (155), Expect = 1e-09
Identities = 44/124 (35%), Positives = 62/124 (50%), Gaps = 6/124 (4%)
Frame = +3
Query: 126 VPTLQLSSGGNIPVVALGTWLGHRPKG-KVVQVTNDTEQ--AVIYALEAGYTHIDTAYKY 296
VP L +G IPV+ GTW R G ND A+ + G HIDTA Y
Sbjct: 4 VPWKSLKNGFAIPVLGQGTW---RMGGVDTPDTANDDADIAAIRRGIATGLCHIDTAEMY 60
Query: 297 G---IEDQVGRALTKKFSEGLKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDL 467
E+ VG A+ +G++R F+T K+W ++ + V+ A SL+ L +Y+DL
Sbjct: 61 AGGHAEELVGIAMK---GQGIRRADYFLTDKVWKTHLRYDDVLRAAEASLKRLGTDYIDL 117
Query: 468 YLIH 479
YLIH
Sbjct: 118 YLIH 121
>UniRef50_Q17DN1 Cluster: Aldo-keto reductase; n=1; Aedes
aegypti|Rep: Aldo-keto reductase - Aedes aegypti
(Yellowfever mosquito)
Length = 284
Score = 66.5 bits (155), Expect = 1e-09
Identities = 36/85 (42%), Positives = 52/85 (61%), Gaps = 1/85 (1%)
Frame = +3
Query: 129 PTLQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIED 308
P ++L++G +PV+ LGTWL +G +A+ A++AGY HIDTAY Y E
Sbjct: 6 PMVKLNNGLEMPVLGLGTWLSKEGEGV---------EAIKAAIDAGYRHIDTAYFYQNEK 56
Query: 309 QVGRALTKKFSEGLK-RESIFITTK 380
+VG A+ K EG+ RE +F+TTK
Sbjct: 57 EVGEAIRAKIEEGVVCREDLFVTTK 81
Database: uniref50
Posted date: Oct 5, 2007 11:19 AM
Number of letters in database: 575,637,011
Number of sequences in database: 1,657,284
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 798,803,387
Number of Sequences: 1657284
Number of extensions: 15721103
Number of successful extensions: 43983
Number of sequences better than 10.0: 500
Number of HSP's better than 10.0 without gapping: 41960
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 43428
length of database: 575,637,011
effective HSP length: 101
effective length of database: 408,251,327
effective search space used: 96347313172
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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