Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= I10A02NGRL0008_D21
(268 letters)
Database: human
237,096 sequences; 76,859,062 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
M23294-1|AAA52645.1| 556|Homo sapiens beta-hexosaminidase beta-... 120 8e-28
M19735-1|AAA68620.1| 544|Homo sapiens beta-hexosaminidase beta-... 120 8e-28
M13519-1|AAA51828.1| 572|Homo sapiens HEXB protein. 120 8e-28
BT009919-1|AAP88921.1| 556|Homo sapiens hexosaminidase B (beta ... 120 8e-28
BC017378-1|AAH17378.1| 556|Homo sapiens hexosaminidase B (beta ... 120 8e-28
AF378118-1|AAM46114.1| 556|Homo sapiens cervical cancer proto-o... 120 8e-28
S62076-1|AAD13932.1| 529|Homo sapiens HEXA protein. 114 5e-26
M16424-1|AAB00965.1| 529|Homo sapiens HEXA protein. 114 5e-26
M13520-1|AAA51827.1| 490|Homo sapiens HEXA protein. 114 5e-26
BC084537-1|AAH84537.1| 529|Homo sapiens hexosaminidase A (alpha... 114 5e-26
BC018927-1|AAH18927.1| 529|Homo sapiens hexosaminidase A (alpha... 114 5e-26
BC001138-1|AAH01138.2| 409|Homo sapiens HEXA protein protein. 114 5e-26
AK222502-1|BAD96222.1| 529|Homo sapiens hexosaminidase A prepro... 114 5e-26
AY643499-1|AAV48875.1| 331|Homo sapiens ENC-1AS protein. 110 9e-25
M34906-1|AAA51829.1| 58|Homo sapiens beta-hexosaminidase beta-... 81 8e-16
BC021030-1|AAH21030.1| 309|Homo sapiens HEXA protein protein. 61 7e-10
>M23294-1|AAA52645.1| 556|Homo sapiens beta-hexosaminidase
beta-subunit protein.
Length = 556
Score = 120 bits (289), Expect = 8e-28
Identities = 53/81 (65%), Positives = 62/81 (76%)
Frame = +2
Query: 5 ILKNIDAMAANKMNVLHWHIVDDQSFPYHSEKFPELSRLGAYHPTLVYTKRDIEIVVKHA 184
ILK +DAMA NK NVLHWHIVDDQSFPY S FPELS G+Y + VYT D+ +V+++A
Sbjct: 219 ILKTLDAMAFNKFNVLHWHIVDDQSFPYQSITFPELSNKGSYSLSHVYTPNDVRMVIEYA 278
Query: 185 AKRGVRVLPEFDVPRHTSSWG 247
RG+RVLPEFD P HT SWG
Sbjct: 279 RLRGIRVLPEFDTPGHTLSWG 299
>M19735-1|AAA68620.1| 544|Homo sapiens beta-hexosaminidase
beta-subunit protein.
Length = 544
Score = 120 bits (289), Expect = 8e-28
Identities = 53/81 (65%), Positives = 62/81 (76%)
Frame = +2
Query: 5 ILKNIDAMAANKMNVLHWHIVDDQSFPYHSEKFPELSRLGAYHPTLVYTKRDIEIVVKHA 184
ILK +DAMA NK NVLHWHIVDDQSFPY S FPELS G+Y + VYT D+ +V+++A
Sbjct: 207 ILKTLDAMAFNKFNVLHWHIVDDQSFPYQSITFPELSNKGSYSLSHVYTPNDVRMVIEYA 266
Query: 185 AKRGVRVLPEFDVPRHTSSWG 247
RG+RVLPEFD P HT SWG
Sbjct: 267 RLRGIRVLPEFDTPGHTLSWG 287
>M13519-1|AAA51828.1| 572|Homo sapiens HEXB protein.
Length = 572
Score = 120 bits (289), Expect = 8e-28
Identities = 53/81 (65%), Positives = 62/81 (76%)
Frame = +2
Query: 5 ILKNIDAMAANKMNVLHWHIVDDQSFPYHSEKFPELSRLGAYHPTLVYTKRDIEIVVKHA 184
ILK +DAMA NK NVLHWHIVDDQSFPY S FPELS G+Y + VYT D+ +V+++A
Sbjct: 235 ILKTLDAMAFNKFNVLHWHIVDDQSFPYQSITFPELSNKGSYSLSHVYTPNDVRMVIEYA 294
Query: 185 AKRGVRVLPEFDVPRHTSSWG 247
RG+RVLPEFD P HT SWG
Sbjct: 295 RLRGIRVLPEFDTPGHTLSWG 315
>BT009919-1|AAP88921.1| 556|Homo sapiens hexosaminidase B (beta
polypeptide) protein.
Length = 556
Score = 120 bits (289), Expect = 8e-28
Identities = 53/81 (65%), Positives = 62/81 (76%)
Frame = +2
Query: 5 ILKNIDAMAANKMNVLHWHIVDDQSFPYHSEKFPELSRLGAYHPTLVYTKRDIEIVVKHA 184
ILK +DAMA NK NVLHWHIVDDQSFPY S FPELS G+Y + VYT D+ +V+++A
Sbjct: 219 ILKTLDAMAFNKFNVLHWHIVDDQSFPYQSITFPELSNKGSYSLSHVYTPNDVRMVIEYA 278
Query: 185 AKRGVRVLPEFDVPRHTSSWG 247
RG+RVLPEFD P HT SWG
Sbjct: 279 RLRGIRVLPEFDTPGHTLSWG 299
>BC017378-1|AAH17378.1| 556|Homo sapiens hexosaminidase B (beta
polypeptide) protein.
Length = 556
Score = 120 bits (289), Expect = 8e-28
Identities = 53/81 (65%), Positives = 62/81 (76%)
Frame = +2
Query: 5 ILKNIDAMAANKMNVLHWHIVDDQSFPYHSEKFPELSRLGAYHPTLVYTKRDIEIVVKHA 184
ILK +DAMA NK NVLHWHIVDDQSFPY S FPELS G+Y + VYT D+ +V+++A
Sbjct: 219 ILKTLDAMAFNKFNVLHWHIVDDQSFPYQSITFPELSNKGSYSLSHVYTPNDVRMVIEYA 278
Query: 185 AKRGVRVLPEFDVPRHTSSWG 247
RG+RVLPEFD P HT SWG
Sbjct: 279 RLRGIRVLPEFDTPGHTLSWG 299
>AF378118-1|AAM46114.1| 556|Homo sapiens cervical cancer
proto-oncogene 7 protein.
Length = 556
Score = 120 bits (289), Expect = 8e-28
Identities = 53/81 (65%), Positives = 62/81 (76%)
Frame = +2
Query: 5 ILKNIDAMAANKMNVLHWHIVDDQSFPYHSEKFPELSRLGAYHPTLVYTKRDIEIVVKHA 184
ILK +DAMA NK NVLHWHIVDDQSFPY S FPELS G+Y + VYT D+ +V+++A
Sbjct: 219 ILKTLDAMAFNKFNVLHWHIVDDQSFPYQSITFPELSNKGSYSLSHVYTPNDVRMVIEYA 278
Query: 185 AKRGVRVLPEFDVPRHTSSWG 247
RG+RVLPEFD P HT SWG
Sbjct: 279 RLRGIRVLPEFDTPGHTLSWG 299
>S62076-1|AAD13932.1| 529|Homo sapiens HEXA protein.
Length = 529
Score = 114 bits (274), Expect = 5e-26
Identities = 50/89 (56%), Positives = 64/89 (71%), Gaps = 1/89 (1%)
Frame = +2
Query: 5 ILKNIDAMAANKMNVLHWHIVDDQSFPYHSEKFPELSRLGAYHP-TLVYTKRDIEIVVKH 181
IL +D MA NK+NV HWH+VDD SFPY S FPEL R G+Y+P T +YT +D++ V+++
Sbjct: 186 ILDTLDVMAYNKLNVFHWHLVDDPSFPYESFTFPELMRKGSYNPVTHIYTAQDVKEVIEY 245
Query: 182 AAKRGVRVLPEFDVPRHTSSWGVAFPSIL 268
A RG+RVL EFD P HT SWG P +L
Sbjct: 246 ARLRGIRVLAEFDTPGHTLSWGPGIPGLL 274
>M16424-1|AAB00965.1| 529|Homo sapiens HEXA protein.
Length = 529
Score = 114 bits (274), Expect = 5e-26
Identities = 50/89 (56%), Positives = 64/89 (71%), Gaps = 1/89 (1%)
Frame = +2
Query: 5 ILKNIDAMAANKMNVLHWHIVDDQSFPYHSEKFPELSRLGAYHP-TLVYTKRDIEIVVKH 181
IL +D MA NK+NV HWH+VDD SFPY S FPEL R G+Y+P T +YT +D++ V+++
Sbjct: 186 ILDTLDVMAYNKLNVFHWHLVDDPSFPYESFTFPELMRKGSYNPVTHIYTAQDVKEVIEY 245
Query: 182 AAKRGVRVLPEFDVPRHTSSWGVAFPSIL 268
A RG+RVL EFD P HT SWG P +L
Sbjct: 246 ARLRGIRVLAEFDTPGHTLSWGPGIPGLL 274
>M13520-1|AAA51827.1| 490|Homo sapiens HEXA protein.
Length = 490
Score = 114 bits (274), Expect = 5e-26
Identities = 50/89 (56%), Positives = 64/89 (71%), Gaps = 1/89 (1%)
Frame = +2
Query: 5 ILKNIDAMAANKMNVLHWHIVDDQSFPYHSEKFPELSRLGAYHP-TLVYTKRDIEIVVKH 181
IL +D MA NK+NV HWH+VDD SFPY S FPEL R G+Y+P T +YT +D++ V+++
Sbjct: 147 ILDTLDVMAYNKLNVFHWHLVDDPSFPYESFTFPELMRKGSYNPVTHIYTAQDVKEVIEY 206
Query: 182 AAKRGVRVLPEFDVPRHTSSWGVAFPSIL 268
A RG+RVL EFD P HT SWG P +L
Sbjct: 207 ARLRGIRVLAEFDTPGHTLSWGPGIPGLL 235
>BC084537-1|AAH84537.1| 529|Homo sapiens hexosaminidase A (alpha
polypeptide) protein.
Length = 529
Score = 114 bits (274), Expect = 5e-26
Identities = 50/89 (56%), Positives = 64/89 (71%), Gaps = 1/89 (1%)
Frame = +2
Query: 5 ILKNIDAMAANKMNVLHWHIVDDQSFPYHSEKFPELSRLGAYHP-TLVYTKRDIEIVVKH 181
IL +D MA NK+NV HWH+VDD SFPY S FPEL R G+Y+P T +YT +D++ V+++
Sbjct: 186 ILDTLDVMAYNKLNVFHWHLVDDPSFPYESFTFPELMRKGSYNPVTHIYTAQDVKEVIEY 245
Query: 182 AAKRGVRVLPEFDVPRHTSSWGVAFPSIL 268
A RG+RVL EFD P HT SWG P +L
Sbjct: 246 ARLRGIRVLAEFDTPGHTLSWGPGIPGLL 274
>BC018927-1|AAH18927.1| 529|Homo sapiens hexosaminidase A (alpha
polypeptide) protein.
Length = 529
Score = 114 bits (274), Expect = 5e-26
Identities = 50/89 (56%), Positives = 64/89 (71%), Gaps = 1/89 (1%)
Frame = +2
Query: 5 ILKNIDAMAANKMNVLHWHIVDDQSFPYHSEKFPELSRLGAYHP-TLVYTKRDIEIVVKH 181
IL +D MA NK+NV HWH+VDD SFPY S FPEL R G+Y+P T +YT +D++ V+++
Sbjct: 186 ILDTLDVMAYNKLNVFHWHLVDDPSFPYESFTFPELMRKGSYNPVTHIYTAQDVKEVIEY 245
Query: 182 AAKRGVRVLPEFDVPRHTSSWGVAFPSIL 268
A RG+RVL EFD P HT SWG P +L
Sbjct: 246 ARLRGIRVLAEFDTPGHTLSWGPGIPGLL 274
>BC001138-1|AAH01138.2| 409|Homo sapiens HEXA protein protein.
Length = 409
Score = 114 bits (274), Expect = 5e-26
Identities = 50/89 (56%), Positives = 64/89 (71%), Gaps = 1/89 (1%)
Frame = +2
Query: 5 ILKNIDAMAANKMNVLHWHIVDDQSFPYHSEKFPELSRLGAYHP-TLVYTKRDIEIVVKH 181
IL +D MA NK+NV HWH+VDD SFPY S FPEL R G+Y+P T +YT +D++ V+++
Sbjct: 66 ILDTLDVMAYNKLNVFHWHLVDDPSFPYESFTFPELMRKGSYNPVTHIYTAQDVKEVIEY 125
Query: 182 AAKRGVRVLPEFDVPRHTSSWGVAFPSIL 268
A RG+RVL EFD P HT SWG P +L
Sbjct: 126 ARLRGIRVLAEFDTPGHTLSWGPGIPGLL 154
>AK222502-1|BAD96222.1| 529|Homo sapiens hexosaminidase A
preproprotein variant protein.
Length = 529
Score = 114 bits (274), Expect = 5e-26
Identities = 50/89 (56%), Positives = 64/89 (71%), Gaps = 1/89 (1%)
Frame = +2
Query: 5 ILKNIDAMAANKMNVLHWHIVDDQSFPYHSEKFPELSRLGAYHP-TLVYTKRDIEIVVKH 181
IL +D MA NK+NV HWH+VDD SFPY S FPEL R G+Y+P T +YT +D++ V+++
Sbjct: 186 ILDTLDVMAYNKLNVFHWHLVDDPSFPYESFTFPELMRKGSYNPVTHIYTAQDVKEVIEY 245
Query: 182 AAKRGVRVLPEFDVPRHTSSWGVAFPSIL 268
A RG+RVL EFD P HT SWG P +L
Sbjct: 246 ARLRGIRVLAEFDTPGHTLSWGPGIPGLL 274
>AY643499-1|AAV48875.1| 331|Homo sapiens ENC-1AS protein.
Length = 331
Score = 110 bits (264), Expect = 9e-25
Identities = 48/74 (64%), Positives = 56/74 (75%)
Frame = +2
Query: 26 MAANKMNVLHWHIVDDQSFPYHSEKFPELSRLGAYHPTLVYTKRDIEIVVKHAAKRGVRV 205
MA NK NVLHWHIVDDQSFPY S FPELS G+Y + VYT D+ +V+++A RG+RV
Sbjct: 1 MAFNKFNVLHWHIVDDQSFPYQSITFPELSNKGSYSLSHVYTPNDVRMVIEYARLRGIRV 60
Query: 206 LPEFDVPRHTSSWG 247
LPEFD P HT SWG
Sbjct: 61 LPEFDTPGHTLSWG 74
>M34906-1|AAA51829.1| 58|Homo sapiens beta-hexosaminidase
beta-subunit protein.
Length = 58
Score = 80.6 bits (190), Expect = 8e-16
Identities = 35/58 (60%), Positives = 43/58 (74%)
Frame = +2
Query: 26 MAANKMNVLHWHIVDDQSFPYHSEKFPELSRLGAYHPTLVYTKRDIEIVVKHAAKRGV 199
MA NK NVLHWHIVDDQSFPY S FPELS G+Y + VYT D+ +V+++A RG+
Sbjct: 1 MAFNKFNVLHWHIVDDQSFPYQSITFPELSNKGSYSLSHVYTPNDVRMVIEYARLRGI 58
>BC021030-1|AAH21030.1| 309|Homo sapiens HEXA protein protein.
Length = 309
Score = 60.9 bits (141), Expect = 7e-10
Identities = 26/52 (50%), Positives = 37/52 (71%), Gaps = 1/52 (1%)
Frame = +2
Query: 116 RLGAYHP-TLVYTKRDIEIVVKHAAKRGVRVLPEFDVPRHTSSWGVAFPSIL 268
R G+Y+P T +YT +D++ V+++A RG+RVL EFD P HT SWG P +L
Sbjct: 3 RTGSYNPVTHIYTAQDVKEVIEYARLRGIRVLAEFDTPGHTLSWGPGIPGLL 54
Database: human
Posted date: Oct 23, 2007 1:18 PM
Number of letters in database: 76,859,062
Number of sequences in database: 237,096
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 38,525,279
Number of Sequences: 237096
Number of extensions: 688620
Number of successful extensions: 1197
Number of sequences better than 10.0: 16
Number of HSP's better than 10.0 without gapping: 1172
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 1190
length of database: 76,859,062
effective HSP length: 66
effective length of database: 61,210,726
effective search space used: 1346635972
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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