Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= I10A02NGRL0007_M21
(598 letters)
Database: human
237,096 sequences; 76,859,062 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
Y14487-1|CAB54840.1| 347|Homo sapiens cytosolic serine hydroxym... 318 1e-86
Y14485-1|CAB54838.1| 483|Homo sapiens cytosolic serine hydroxym... 318 1e-86
L23928-3|AAA36019.1| 403|Homo sapiens serine hydroxymethyltrans... 318 1e-86
L23928-2|AAA36018.1| 444|Homo sapiens serine hydroxymethyltrans... 318 1e-86
L23928-1|AAA36020.1| 483|Homo sapiens serine hydroxymethyltrans... 318 1e-86
L11931-1|AAA63257.1| 483|Homo sapiens serine hydroxymethyltrans... 318 1e-86
BC038598-1|AAH38598.1| 483|Homo sapiens serine hydroxymethyltra... 318 1e-86
BC022874-1|AAH22874.1| 444|Homo sapiens serine hydroxymethyltra... 318 1e-86
BC007979-1|AAH07979.1| 483|Homo sapiens serine hydroxymethyltra... 318 1e-86
AK223552-1|BAD97272.1| 483|Homo sapiens serine hydroxymethyltra... 318 1e-86
U23143-1|AAA64572.1| 483|Homo sapiens mitochondrial serine hydr... 286 4e-77
L11932-1|AAA63258.1| 474|Homo sapiens serine hydroxymethyltrans... 286 4e-77
BT006866-1|AAP35512.1| 504|Homo sapiens serine hydroxymethyltra... 286 4e-77
BC044211-1|AAH44211.1| 504|Homo sapiens serine hydroxymethyltra... 286 4e-77
BC013677-1|AAH13677.1| 504|Homo sapiens serine hydroxymethyltra... 286 4e-77
BC011911-1|AAH11911.1| 504|Homo sapiens serine hydroxymethyltra... 286 4e-77
AK223555-1|BAD97275.1| 504|Homo sapiens serine hydroxymethyltra... 286 4e-77
BC032584-1|AAH32584.1| 494|Homo sapiens SHMT2 protein protein. 258 8e-69
BC091501-1|AAH91501.1| 480|Homo sapiens SHMT2 protein protein. 229 8e-60
Y14486-1|CAB54839.1| 310|Homo sapiens cytosolic serine hydroxym... 82 1e-15
Y14488-1|CAB54841.1| 129|Homo sapiens 14 kDa protein protein. 60 6e-09
AK055053-1|BAB70847.1| 135|Homo sapiens protein. 35 0.19
>Y14487-1|CAB54840.1| 347|Homo sapiens cytosolic serine
hydroxymethyltransferase protein.
Length = 347
Score = 318 bits (781), Expect = 1e-86
Identities = 146/198 (73%), Positives = 167/198 (84%)
Frame = +3
Query: 3 DPELFNLITKEKKRQQAGLEMIASENFTSVPVLQCLSSCLHNKYSEGMPYQRYYGGNEFI 182
D E++N+I KE RQ+ GLE+IASENF S VL+ L SCL+NKYSEG P QRYYGG EFI
Sbjct: 30 DVEVYNIIKKESNRQRVGLELIASENFASRAVLEALGSCLNNKYSEGYPGQRYYGGTEFI 89
Query: 183 DEIEILAQNRSLETYKLNPEEWGVNVQPYSGSPANFAVYTGVVEPHGRIMGLDLPDGGHL 362
DE+E L Q R+L+ YKL+P+ WGVNVQPYSGSPANFAVYT +VEPHGRIMGLDLPDGGHL
Sbjct: 90 DELETLCQKRALQAYKLDPQCWGVNVQPYSGSPANFAVYTALVEPHGRIMGLDLPDGGHL 149
Query: 363 THGFFTANKKISATSIFFESMPYKVDPTTGLIDYDKLAETAKLFKPRVIIAGMSCYSRCL 542
THGF T KKISATSIFFESMPYKV+P TG I+YD+L E A+LF P++IIAG SCYSR L
Sbjct: 150 THGFMTDKKKISATSIFFESMPYKVNPDTGYINYDQLEENARLFHPKLIIAGTSCYSRNL 209
Query: 543 DYERFRQIADENGAYLMA 596
+Y R R+IADENGAYLMA
Sbjct: 210 EYARLRKIADENGAYLMA 227
>Y14485-1|CAB54838.1| 483|Homo sapiens cytosolic serine
hydroxymethyltransferase protein.
Length = 483
Score = 318 bits (781), Expect = 1e-86
Identities = 146/198 (73%), Positives = 167/198 (84%)
Frame = +3
Query: 3 DPELFNLITKEKKRQQAGLEMIASENFTSVPVLQCLSSCLHNKYSEGMPYQRYYGGNEFI 182
D E++N+I KE RQ+ GLE+IASENF S VL+ L SCL+NKYSEG P QRYYGG EFI
Sbjct: 30 DVEVYNIIKKESNRQRVGLELIASENFASRAVLEALGSCLNNKYSEGYPGQRYYGGTEFI 89
Query: 183 DEIEILAQNRSLETYKLNPEEWGVNVQPYSGSPANFAVYTGVVEPHGRIMGLDLPDGGHL 362
DE+E L Q R+L+ YKL+P+ WGVNVQPYSGSPANFAVYT +VEPHGRIMGLDLPDGGHL
Sbjct: 90 DELETLCQKRALQAYKLDPQCWGVNVQPYSGSPANFAVYTALVEPHGRIMGLDLPDGGHL 149
Query: 363 THGFFTANKKISATSIFFESMPYKVDPTTGLIDYDKLAETAKLFKPRVIIAGMSCYSRCL 542
THGF T KKISATSIFFESMPYKV+P TG I+YD+L E A+LF P++IIAG SCYSR L
Sbjct: 150 THGFMTDKKKISATSIFFESMPYKVNPDTGYINYDQLEENARLFHPKLIIAGTSCYSRNL 209
Query: 543 DYERFRQIADENGAYLMA 596
+Y R R+IADENGAYLMA
Sbjct: 210 EYARLRKIADENGAYLMA 227
>L23928-3|AAA36019.1| 403|Homo sapiens serine
hydroxymethyltransferase protein.
Length = 403
Score = 318 bits (781), Expect = 1e-86
Identities = 146/198 (73%), Positives = 167/198 (84%)
Frame = +3
Query: 3 DPELFNLITKEKKRQQAGLEMIASENFTSVPVLQCLSSCLHNKYSEGMPYQRYYGGNEFI 182
D E++N+I KE RQ+ GLE+IASENF S VL+ L SCL+NKYSEG P QRYYGG EFI
Sbjct: 30 DVEVYNIIKKESNRQRVGLELIASENFASRAVLEALGSCLNNKYSEGYPGQRYYGGTEFI 89
Query: 183 DEIEILAQNRSLETYKLNPEEWGVNVQPYSGSPANFAVYTGVVEPHGRIMGLDLPDGGHL 362
DE+E L Q R+L+ YKL+P+ WGVNVQPYSGSPANFAVYT +VEPHGRIMGLDLPDGGHL
Sbjct: 90 DELETLCQKRALQAYKLDPQCWGVNVQPYSGSPANFAVYTALVEPHGRIMGLDLPDGGHL 149
Query: 363 THGFFTANKKISATSIFFESMPYKVDPTTGLIDYDKLAETAKLFKPRVIIAGMSCYSRCL 542
THGF T KKISATSIFFESMPYKV+P TG I+YD+L E A+LF P++IIAG SCYSR L
Sbjct: 150 THGFMTDKKKISATSIFFESMPYKVNPDTGYINYDQLEENARLFHPKLIIAGTSCYSRNL 209
Query: 543 DYERFRQIADENGAYLMA 596
+Y R R+IADENGAYLMA
Sbjct: 210 EYARLRKIADENGAYLMA 227
>L23928-2|AAA36018.1| 444|Homo sapiens serine
hydroxymethyltransferase protein.
Length = 444
Score = 318 bits (781), Expect = 1e-86
Identities = 146/198 (73%), Positives = 167/198 (84%)
Frame = +3
Query: 3 DPELFNLITKEKKRQQAGLEMIASENFTSVPVLQCLSSCLHNKYSEGMPYQRYYGGNEFI 182
D E++N+I KE RQ+ GLE+IASENF S VL+ L SCL+NKYSEG P QRYYGG EFI
Sbjct: 30 DVEVYNIIKKESNRQRVGLELIASENFASRAVLEALGSCLNNKYSEGYPGQRYYGGTEFI 89
Query: 183 DEIEILAQNRSLETYKLNPEEWGVNVQPYSGSPANFAVYTGVVEPHGRIMGLDLPDGGHL 362
DE+E L Q R+L+ YKL+P+ WGVNVQPYSGSPANFAVYT +VEPHGRIMGLDLPDGGHL
Sbjct: 90 DELETLCQKRALQAYKLDPQCWGVNVQPYSGSPANFAVYTALVEPHGRIMGLDLPDGGHL 149
Query: 363 THGFFTANKKISATSIFFESMPYKVDPTTGLIDYDKLAETAKLFKPRVIIAGMSCYSRCL 542
THGF T KKISATSIFFESMPYKV+P TG I+YD+L E A+LF P++IIAG SCYSR L
Sbjct: 150 THGFMTDKKKISATSIFFESMPYKVNPDTGYINYDQLEENARLFHPKLIIAGTSCYSRNL 209
Query: 543 DYERFRQIADENGAYLMA 596
+Y R R+IADENGAYLMA
Sbjct: 210 EYARLRKIADENGAYLMA 227
>L23928-1|AAA36020.1| 483|Homo sapiens serine
hydroxymethyltransferase protein.
Length = 483
Score = 318 bits (781), Expect = 1e-86
Identities = 146/198 (73%), Positives = 167/198 (84%)
Frame = +3
Query: 3 DPELFNLITKEKKRQQAGLEMIASENFTSVPVLQCLSSCLHNKYSEGMPYQRYYGGNEFI 182
D E++N+I KE RQ+ GLE+IASENF S VL+ L SCL+NKYSEG P QRYYGG EFI
Sbjct: 30 DVEVYNIIKKESNRQRVGLELIASENFASRAVLEALGSCLNNKYSEGYPGQRYYGGTEFI 89
Query: 183 DEIEILAQNRSLETYKLNPEEWGVNVQPYSGSPANFAVYTGVVEPHGRIMGLDLPDGGHL 362
DE+E L Q R+L+ YKL+P+ WGVNVQPYSGSPANFAVYT +VEPHGRIMGLDLPDGGHL
Sbjct: 90 DELETLCQKRALQAYKLDPQCWGVNVQPYSGSPANFAVYTALVEPHGRIMGLDLPDGGHL 149
Query: 363 THGFFTANKKISATSIFFESMPYKVDPTTGLIDYDKLAETAKLFKPRVIIAGMSCYSRCL 542
THGF T KKISATSIFFESMPYKV+P TG I+YD+L E A+LF P++IIAG SCYSR L
Sbjct: 150 THGFMTDKKKISATSIFFESMPYKVNPDTGYINYDQLEENARLFHPKLIIAGTSCYSRNL 209
Query: 543 DYERFRQIADENGAYLMA 596
+Y R R+IADENGAYLMA
Sbjct: 210 EYARLRKIADENGAYLMA 227
>L11931-1|AAA63257.1| 483|Homo sapiens serine
hydroxymethyltransferase protein.
Length = 483
Score = 318 bits (781), Expect = 1e-86
Identities = 146/198 (73%), Positives = 167/198 (84%)
Frame = +3
Query: 3 DPELFNLITKEKKRQQAGLEMIASENFTSVPVLQCLSSCLHNKYSEGMPYQRYYGGNEFI 182
D E++N+I KE RQ+ GLE+IASENF S VL+ L SCL+NKYSEG P QRYYGG EFI
Sbjct: 30 DVEVYNIIKKESNRQRVGLELIASENFASRAVLEALGSCLNNKYSEGYPGQRYYGGTEFI 89
Query: 183 DEIEILAQNRSLETYKLNPEEWGVNVQPYSGSPANFAVYTGVVEPHGRIMGLDLPDGGHL 362
DE+E L Q R+L+ YKL+P+ WGVNVQPYSGSPANFAVYT +VEPHGRIMGLDLPDGGHL
Sbjct: 90 DELETLCQKRALQAYKLDPQCWGVNVQPYSGSPANFAVYTALVEPHGRIMGLDLPDGGHL 149
Query: 363 THGFFTANKKISATSIFFESMPYKVDPTTGLIDYDKLAETAKLFKPRVIIAGMSCYSRCL 542
THGF T KKISATSIFFESMPYKV+P TG I+YD+L E A+LF P++IIAG SCYSR L
Sbjct: 150 THGFMTDKKKISATSIFFESMPYKVNPDTGYINYDQLEENARLFHPKLIIAGTSCYSRNL 209
Query: 543 DYERFRQIADENGAYLMA 596
+Y R R+IADENGAYLMA
Sbjct: 210 EYARLRKIADENGAYLMA 227
>BC038598-1|AAH38598.1| 483|Homo sapiens serine
hydroxymethyltransferase 1 (soluble) protein.
Length = 483
Score = 318 bits (781), Expect = 1e-86
Identities = 146/198 (73%), Positives = 167/198 (84%)
Frame = +3
Query: 3 DPELFNLITKEKKRQQAGLEMIASENFTSVPVLQCLSSCLHNKYSEGMPYQRYYGGNEFI 182
D E++N+I KE RQ+ GLE+IASENF S VL+ L SCL+NKYSEG P QRYYGG EFI
Sbjct: 30 DVEVYNIIKKESNRQRVGLELIASENFASRAVLEALGSCLNNKYSEGYPGQRYYGGTEFI 89
Query: 183 DEIEILAQNRSLETYKLNPEEWGVNVQPYSGSPANFAVYTGVVEPHGRIMGLDLPDGGHL 362
DE+E L Q R+L+ YKL+P+ WGVNVQPYSGSPANFAVYT +VEPHGRIMGLDLPDGGHL
Sbjct: 90 DELETLCQKRALQAYKLDPQCWGVNVQPYSGSPANFAVYTALVEPHGRIMGLDLPDGGHL 149
Query: 363 THGFFTANKKISATSIFFESMPYKVDPTTGLIDYDKLAETAKLFKPRVIIAGMSCYSRCL 542
THGF T KKISATSIFFESMPYKV+P TG I+YD+L E A+LF P++IIAG SCYSR L
Sbjct: 150 THGFMTDKKKISATSIFFESMPYKVNPDTGYINYDQLEENARLFHPKLIIAGTSCYSRNL 209
Query: 543 DYERFRQIADENGAYLMA 596
+Y R R+IADENGAYLMA
Sbjct: 210 EYARLRKIADENGAYLMA 227
>BC022874-1|AAH22874.1| 444|Homo sapiens serine
hydroxymethyltransferase 1 (soluble) protein.
Length = 444
Score = 318 bits (781), Expect = 1e-86
Identities = 146/198 (73%), Positives = 167/198 (84%)
Frame = +3
Query: 3 DPELFNLITKEKKRQQAGLEMIASENFTSVPVLQCLSSCLHNKYSEGMPYQRYYGGNEFI 182
D E++N+I KE RQ+ GLE+IASENF S VL+ L SCL+NKYSEG P QRYYGG EFI
Sbjct: 30 DVEVYNIIKKESNRQRVGLELIASENFASRAVLEALGSCLNNKYSEGYPGQRYYGGTEFI 89
Query: 183 DEIEILAQNRSLETYKLNPEEWGVNVQPYSGSPANFAVYTGVVEPHGRIMGLDLPDGGHL 362
DE+E L Q R+L+ YKL+P+ WGVNVQPYSGSPANFAVYT +VEPHGRIMGLDLPDGGHL
Sbjct: 90 DELETLCQKRALQAYKLDPQCWGVNVQPYSGSPANFAVYTALVEPHGRIMGLDLPDGGHL 149
Query: 363 THGFFTANKKISATSIFFESMPYKVDPTTGLIDYDKLAETAKLFKPRVIIAGMSCYSRCL 542
THGF T KKISATSIFFESMPYKV+P TG I+YD+L E A+LF P++IIAG SCYSR L
Sbjct: 150 THGFMTDKKKISATSIFFESMPYKVNPDTGYINYDQLEENARLFHPKLIIAGTSCYSRNL 209
Query: 543 DYERFRQIADENGAYLMA 596
+Y R R+IADENGAYLMA
Sbjct: 210 EYARLRKIADENGAYLMA 227
>BC007979-1|AAH07979.1| 483|Homo sapiens serine
hydroxymethyltransferase 1 (soluble) protein.
Length = 483
Score = 318 bits (781), Expect = 1e-86
Identities = 146/198 (73%), Positives = 167/198 (84%)
Frame = +3
Query: 3 DPELFNLITKEKKRQQAGLEMIASENFTSVPVLQCLSSCLHNKYSEGMPYQRYYGGNEFI 182
D E++N+I KE RQ+ GLE+IASENF S VL+ L SCL+NKYSEG P QRYYGG EFI
Sbjct: 30 DVEVYNIIKKESNRQRVGLELIASENFASRAVLEALGSCLNNKYSEGYPGQRYYGGTEFI 89
Query: 183 DEIEILAQNRSLETYKLNPEEWGVNVQPYSGSPANFAVYTGVVEPHGRIMGLDLPDGGHL 362
DE+E L Q R+L+ YKL+P+ WGVNVQPYSGSPANFAVYT +VEPHGRIMGLDLPDGGHL
Sbjct: 90 DELETLCQKRALQAYKLDPQCWGVNVQPYSGSPANFAVYTALVEPHGRIMGLDLPDGGHL 149
Query: 363 THGFFTANKKISATSIFFESMPYKVDPTTGLIDYDKLAETAKLFKPRVIIAGMSCYSRCL 542
THGF T KKISATSIFFESMPYKV+P TG I+YD+L E A+LF P++IIAG SCYSR L
Sbjct: 150 THGFMTDKKKISATSIFFESMPYKVNPDTGYINYDQLEENARLFHPKLIIAGTSCYSRNL 209
Query: 543 DYERFRQIADENGAYLMA 596
+Y R R+IADENGAYLMA
Sbjct: 210 EYARLRKIADENGAYLMA 227
>AK223552-1|BAD97272.1| 483|Homo sapiens serine
hydroxymethyltransferase 1 (soluble) isoform 1 variant
protein.
Length = 483
Score = 318 bits (781), Expect = 1e-86
Identities = 146/198 (73%), Positives = 167/198 (84%)
Frame = +3
Query: 3 DPELFNLITKEKKRQQAGLEMIASENFTSVPVLQCLSSCLHNKYSEGMPYQRYYGGNEFI 182
D E++N+I KE RQ+ GLE+IASENF S VL+ L SCL+NKYSEG P QRYYGG EFI
Sbjct: 30 DVEVYNIIKKESNRQRVGLELIASENFASRAVLEALGSCLNNKYSEGYPGQRYYGGTEFI 89
Query: 183 DEIEILAQNRSLETYKLNPEEWGVNVQPYSGSPANFAVYTGVVEPHGRIMGLDLPDGGHL 362
DE+E L Q R+L+ YKL+P+ WGVNVQPYSGSPANFAVYT +VEPHGRIMGLDLPDGGHL
Sbjct: 90 DELETLCQKRALQAYKLDPQCWGVNVQPYSGSPANFAVYTALVEPHGRIMGLDLPDGGHL 149
Query: 363 THGFFTANKKISATSIFFESMPYKVDPTTGLIDYDKLAETAKLFKPRVIIAGMSCYSRCL 542
THGF T KKISATSIFFESMPYKV+P TG I+YD+L E A+LF P++IIAG SCYSR L
Sbjct: 150 THGFMTDKKKISATSIFFESMPYKVNPDTGYINYDQLEENARLFHPKLIIAGTSCYSRNL 209
Query: 543 DYERFRQIADENGAYLMA 596
+Y R R+IADENGAYLMA
Sbjct: 210 EYARLRKIADENGAYLMA 227
>U23143-1|AAA64572.1| 483|Homo sapiens mitochondrial serine
hydroxymethyltransferase protein.
Length = 483
Score = 286 bits (702), Expect = 4e-77
Identities = 129/198 (65%), Positives = 162/198 (81%)
Frame = +3
Query: 3 DPELFNLITKEKKRQQAGLEMIASENFTSVPVLQCLSSCLHNKYSEGMPYQRYYGGNEFI 182
DPE++ L+ +EK RQ GLE+IASENF S L+ L SCL+NKYSEG P +RYYGG E +
Sbjct: 32 DPEMWELLQREKDRQCRGLELIASENFCSRAALEALGSCLNNKYSEGYPGKRYYGGAEVV 91
Query: 183 DEIEILAQNRSLETYKLNPEEWGVNVQPYSGSPANFAVYTGVVEPHGRIMGLDLPDGGHL 362
DEIE+L Q R+LE + L+P +WGVNVQPYSGSPAN AVYT +++PH RIMGLDLPDGGHL
Sbjct: 92 DEIELLCQRRALEAFDLDPAQWGVNVQPYSGSPANLAVYTALLQPHDRIMGLDLPDGGHL 151
Query: 363 THGFFTANKKISATSIFFESMPYKVDPTTGLIDYDKLAETAKLFKPRVIIAGMSCYSRCL 542
THG+ + K+ISATSIFFESMPYK++P TGLIDY++LA TA+LF+PR+IIAG S Y+R +
Sbjct: 152 THGYMSDVKRISATSIFFESMPYKLNPKTGLIDYNQLALTARLFRPRLIIAGTSAYARLI 211
Query: 543 DYERFRQIADENGAYLMA 596
DY R R++ DE A+L+A
Sbjct: 212 DYARMREVCDEVKAHLLA 229
>L11932-1|AAA63258.1| 474|Homo sapiens serine
hydroxymethyltransferase protein.
Length = 474
Score = 286 bits (702), Expect = 4e-77
Identities = 129/198 (65%), Positives = 162/198 (81%)
Frame = +3
Query: 3 DPELFNLITKEKKRQQAGLEMIASENFTSVPVLQCLSSCLHNKYSEGMPYQRYYGGNEFI 182
DPE++ L+ +EK RQ GLE+IASENF S L+ L SCL+NKYSEG P +RYYGG E +
Sbjct: 23 DPEMWELLQREKDRQCRGLELIASENFCSRAALEALGSCLNNKYSEGYPGKRYYGGAEVV 82
Query: 183 DEIEILAQNRSLETYKLNPEEWGVNVQPYSGSPANFAVYTGVVEPHGRIMGLDLPDGGHL 362
DEIE+L Q R+LE + L+P +WGVNVQPYSGSPAN AVYT +++PH RIMGLDLPDGGHL
Sbjct: 83 DEIELLCQRRALEAFDLDPAQWGVNVQPYSGSPANLAVYTALLQPHDRIMGLDLPDGGHL 142
Query: 363 THGFFTANKKISATSIFFESMPYKVDPTTGLIDYDKLAETAKLFKPRVIIAGMSCYSRCL 542
THG+ + K+ISATSIFFESMPYK++P TGLIDY++LA TA+LF+PR+IIAG S Y+R +
Sbjct: 143 THGYMSDVKRISATSIFFESMPYKLNPKTGLIDYNQLALTARLFRPRLIIAGTSAYARLI 202
Query: 543 DYERFRQIADENGAYLMA 596
DY R R++ DE A+L+A
Sbjct: 203 DYARMREVCDEVKAHLLA 220
>BT006866-1|AAP35512.1| 504|Homo sapiens serine
hydroxymethyltransferase 2 (mitochondrial) protein.
Length = 504
Score = 286 bits (702), Expect = 4e-77
Identities = 129/198 (65%), Positives = 162/198 (81%)
Frame = +3
Query: 3 DPELFNLITKEKKRQQAGLEMIASENFTSVPVLQCLSSCLHNKYSEGMPYQRYYGGNEFI 182
DPE++ L+ +EK RQ GLE+IASENF S L+ L SCL+NKYSEG P +RYYGG E +
Sbjct: 53 DPEMWELLQREKDRQCRGLELIASENFCSRAALEALGSCLNNKYSEGYPGKRYYGGAEVV 112
Query: 183 DEIEILAQNRSLETYKLNPEEWGVNVQPYSGSPANFAVYTGVVEPHGRIMGLDLPDGGHL 362
DEIE+L Q R+LE + L+P +WGVNVQPYSGSPAN AVYT +++PH RIMGLDLPDGGHL
Sbjct: 113 DEIELLCQRRALEAFDLDPAQWGVNVQPYSGSPANLAVYTALLQPHDRIMGLDLPDGGHL 172
Query: 363 THGFFTANKKISATSIFFESMPYKVDPTTGLIDYDKLAETAKLFKPRVIIAGMSCYSRCL 542
THG+ + K+ISATSIFFESMPYK++P TGLIDY++LA TA+LF+PR+IIAG S Y+R +
Sbjct: 173 THGYMSDVKRISATSIFFESMPYKLNPKTGLIDYNQLALTARLFRPRLIIAGTSAYARLI 232
Query: 543 DYERFRQIADENGAYLMA 596
DY R R++ DE A+L+A
Sbjct: 233 DYARMREVCDEVKAHLLA 250
>BC044211-1|AAH44211.1| 504|Homo sapiens serine
hydroxymethyltransferase 2 (mitochondrial) protein.
Length = 504
Score = 286 bits (702), Expect = 4e-77
Identities = 129/198 (65%), Positives = 162/198 (81%)
Frame = +3
Query: 3 DPELFNLITKEKKRQQAGLEMIASENFTSVPVLQCLSSCLHNKYSEGMPYQRYYGGNEFI 182
DPE++ L+ +EK RQ GLE+IASENF S L+ L SCL+NKYSEG P +RYYGG E +
Sbjct: 53 DPEMWELLQREKDRQCRGLELIASENFCSRAALEALGSCLNNKYSEGYPGKRYYGGAEVV 112
Query: 183 DEIEILAQNRSLETYKLNPEEWGVNVQPYSGSPANFAVYTGVVEPHGRIMGLDLPDGGHL 362
DEIE+L Q R+LE + L+P +WGVNVQPYSGSPAN AVYT +++PH RIMGLDLPDGGHL
Sbjct: 113 DEIELLCQRRALEAFDLDPAQWGVNVQPYSGSPANLAVYTALLQPHDRIMGLDLPDGGHL 172
Query: 363 THGFFTANKKISATSIFFESMPYKVDPTTGLIDYDKLAETAKLFKPRVIIAGMSCYSRCL 542
THG+ + K+ISATSIFFESMPYK++P TGLIDY++LA TA+LF+PR+IIAG S Y+R +
Sbjct: 173 THGYMSDVKRISATSIFFESMPYKLNPKTGLIDYNQLALTARLFRPRLIIAGTSAYARLI 232
Query: 543 DYERFRQIADENGAYLMA 596
DY R R++ DE A+L+A
Sbjct: 233 DYARMREVCDEVKAHLLA 250
>BC013677-1|AAH13677.1| 504|Homo sapiens serine
hydroxymethyltransferase 2 (mitochondrial) protein.
Length = 504
Score = 286 bits (702), Expect = 4e-77
Identities = 129/198 (65%), Positives = 162/198 (81%)
Frame = +3
Query: 3 DPELFNLITKEKKRQQAGLEMIASENFTSVPVLQCLSSCLHNKYSEGMPYQRYYGGNEFI 182
DPE++ L+ +EK RQ GLE+IASENF S L+ L SCL+NKYSEG P +RYYGG E +
Sbjct: 53 DPEMWELLQREKDRQCRGLELIASENFCSRAALEALGSCLNNKYSEGYPGKRYYGGAEVV 112
Query: 183 DEIEILAQNRSLETYKLNPEEWGVNVQPYSGSPANFAVYTGVVEPHGRIMGLDLPDGGHL 362
DEIE+L Q R+LE + L+P +WGVNVQPYSGSPAN AVYT +++PH RIMGLDLPDGGHL
Sbjct: 113 DEIELLCQRRALEAFDLDPAQWGVNVQPYSGSPANLAVYTALLQPHDRIMGLDLPDGGHL 172
Query: 363 THGFFTANKKISATSIFFESMPYKVDPTTGLIDYDKLAETAKLFKPRVIIAGMSCYSRCL 542
THG+ + K+ISATSIFFESMPYK++P TGLIDY++LA TA+LF+PR+IIAG S Y+R +
Sbjct: 173 THGYMSDVKRISATSIFFESMPYKLNPKTGLIDYNQLALTARLFRPRLIIAGTSAYARLI 232
Query: 543 DYERFRQIADENGAYLMA 596
DY R R++ DE A+L+A
Sbjct: 233 DYARMREVCDEVKAHLLA 250
>BC011911-1|AAH11911.1| 504|Homo sapiens serine
hydroxymethyltransferase 2 (mitochondrial) protein.
Length = 504
Score = 286 bits (702), Expect = 4e-77
Identities = 129/198 (65%), Positives = 162/198 (81%)
Frame = +3
Query: 3 DPELFNLITKEKKRQQAGLEMIASENFTSVPVLQCLSSCLHNKYSEGMPYQRYYGGNEFI 182
DPE++ L+ +EK RQ GLE+IASENF S L+ L SCL+NKYSEG P +RYYGG E +
Sbjct: 53 DPEMWELLQREKDRQCRGLELIASENFCSRAALEALGSCLNNKYSEGYPGKRYYGGAEVV 112
Query: 183 DEIEILAQNRSLETYKLNPEEWGVNVQPYSGSPANFAVYTGVVEPHGRIMGLDLPDGGHL 362
DEIE+L Q R+LE + L+P +WGVNVQPYSGSPAN AVYT +++PH RIMGLDLPDGGHL
Sbjct: 113 DEIELLCQRRALEAFDLDPAQWGVNVQPYSGSPANLAVYTALLQPHDRIMGLDLPDGGHL 172
Query: 363 THGFFTANKKISATSIFFESMPYKVDPTTGLIDYDKLAETAKLFKPRVIIAGMSCYSRCL 542
THG+ + K+ISATSIFFESMPYK++P TGLIDY++LA TA+LF+PR+IIAG S Y+R +
Sbjct: 173 THGYMSDVKRISATSIFFESMPYKLNPKTGLIDYNQLALTARLFRPRLIIAGTSAYARLI 232
Query: 543 DYERFRQIADENGAYLMA 596
DY R R++ DE A+L+A
Sbjct: 233 DYARMREVCDEVKAHLLA 250
>AK223555-1|BAD97275.1| 504|Homo sapiens serine
hydroxymethyltransferase 2 (mitochondrial) variant
protein.
Length = 504
Score = 286 bits (702), Expect = 4e-77
Identities = 129/198 (65%), Positives = 162/198 (81%)
Frame = +3
Query: 3 DPELFNLITKEKKRQQAGLEMIASENFTSVPVLQCLSSCLHNKYSEGMPYQRYYGGNEFI 182
DPE++ L+ +EK RQ GLE+IASENF S L+ L SCL+NKYSEG P +RYYGG E +
Sbjct: 53 DPEMWELLQREKDRQCRGLELIASENFCSRAALEALGSCLNNKYSEGYPGKRYYGGAEVV 112
Query: 183 DEIEILAQNRSLETYKLNPEEWGVNVQPYSGSPANFAVYTGVVEPHGRIMGLDLPDGGHL 362
DEIE+L Q R+LE + L+P +WGVNVQPYSGSPAN AVYT +++PH RIMGLDLPDGGHL
Sbjct: 113 DEIELLCQRRALEAFDLDPAQWGVNVQPYSGSPANLAVYTALLQPHDRIMGLDLPDGGHL 172
Query: 363 THGFFTANKKISATSIFFESMPYKVDPTTGLIDYDKLAETAKLFKPRVIIAGMSCYSRCL 542
THG+ + K+ISATSIFFESMPYK++P TGLIDY++LA TA+LF+PR+IIAG S Y+R +
Sbjct: 173 THGYMSDVKRISATSIFFESMPYKLNPKTGLIDYNQLALTARLFRPRLIIAGTSAYARLI 232
Query: 543 DYERFRQIADENGAYLMA 596
DY R R++ DE A+L+A
Sbjct: 233 DYARMREVCDEVKAHLLA 250
>BC032584-1|AAH32584.1| 494|Homo sapiens SHMT2 protein protein.
Length = 494
Score = 258 bits (633), Expect = 8e-69
Identities = 122/198 (61%), Positives = 153/198 (77%)
Frame = +3
Query: 3 DPELFNLITKEKKRQQAGLEMIASENFTSVPVLQCLSSCLHNKYSEGMPYQRYYGGNEFI 182
DPE++ L+ +EK RQ GLE+IASENF S L+ L SCL+NKYSEG P +RYYGG E +
Sbjct: 53 DPEMWELLQREKDRQCRGLELIASENFCSRAALEALGSCLNNKYSEGYPGKRYYGGAEVV 112
Query: 183 DEIEILAQNRSLETYKLNPEEWGVNVQPYSGSPANFAVYTGVVEPHGRIMGLDLPDGGHL 362
DEIE+L Q R+LE + L+P +WGVNVQPYSGSPAN AVYT +++PH RIMGLDLPDGGHL
Sbjct: 113 DEIELLCQRRALEAFDLDPAQWGVNVQPYSGSPANLAVYTALLQPHDRIMGLDLPDGGHL 172
Query: 363 THGFFTANKKISATSIFFESMPYKVDPTTGLIDYDKLAETAKLFKPRVIIAGMSCYSRCL 542
THG+ + K+ISATSIFFESMPYK++ LA TA+LF+PR+IIAG S Y+R +
Sbjct: 173 THGYMSDVKRISATSIFFESMPYKLN----------LALTARLFRPRLIIAGTSAYARLI 222
Query: 543 DYERFRQIADENGAYLMA 596
DY R R++ DE A+L+A
Sbjct: 223 DYARMREVCDEVKAHLLA 240
>BC091501-1|AAH91501.1| 480|Homo sapiens SHMT2 protein protein.
Length = 480
Score = 229 bits (559), Expect = 8e-60
Identities = 110/200 (55%), Positives = 144/200 (72%), Gaps = 6/200 (3%)
Frame = +3
Query: 15 FNLITKEKKRQQAGLEMIASE--NFTSVPVLQCLSSCLHNKYSEGMPY----QRYYGGNE 176
F L T + R + G + A + +L+C S C + + + QRYYGG E
Sbjct: 27 FGLSTATQPRLRLGKQTGAGQARRACRTVILRCGSCCRGRRTGSVVAWSSLPQRYYGGAE 86
Query: 177 FIDEIEILAQNRSLETYKLNPEEWGVNVQPYSGSPANFAVYTGVVEPHGRIMGLDLPDGG 356
+DEIE+L Q R+LE + L+P +WGVNVQPYSGSPAN AVYT +++PH RIMGLDLPDGG
Sbjct: 87 VVDEIELLCQRRALEAFDLDPAQWGVNVQPYSGSPANLAVYTALLQPHDRIMGLDLPDGG 146
Query: 357 HLTHGFFTANKKISATSIFFESMPYKVDPTTGLIDYDKLAETAKLFKPRVIIAGMSCYSR 536
HLTHG+ + K+ISATSIFFESMPYK++P TGLIDY++LA TA+LF+PR+IIAG S Y+R
Sbjct: 147 HLTHGYMSDVKRISATSIFFESMPYKLNPKTGLIDYNQLALTARLFRPRLIIAGTSAYAR 206
Query: 537 CLDYERFRQIADENGAYLMA 596
+DY R R++ DE A+L+A
Sbjct: 207 LIDYARMREVCDEVKAHLLA 226
>Y14486-1|CAB54839.1| 310|Homo sapiens cytosolic serine
hydroxymethyltransferase protein.
Length = 310
Score = 82.2 bits (194), Expect = 1e-15
Identities = 37/54 (68%), Positives = 45/54 (83%)
Frame = +3
Query: 435 VDPTTGLIDYDKLAETAKLFKPRVIIAGMSCYSRCLDYERFRQIADENGAYLMA 596
V+P TG I+YD+L E A+LF P++IIAG SCYSR L+Y R R+IADENGAYLMA
Sbjct: 1 VNPDTGYINYDQLEENARLFHPKLIIAGTSCYSRNLEYARLRKIADENGAYLMA 54
>Y14488-1|CAB54841.1| 129|Homo sapiens 14 kDa protein protein.
Length = 129
Score = 60.1 bits (139), Expect = 6e-09
Identities = 24/37 (64%), Positives = 30/37 (81%)
Frame = +3
Query: 156 RYYGGNEFIDEIEILAQNRSLETYKLNPEEWGVNVQP 266
RYYGG EFIDE+E L Q R+L+ YKL+P+ WGV+V P
Sbjct: 65 RYYGGTEFIDELETLCQKRALQAYKLDPQCWGVDVHP 101
>AK055053-1|BAB70847.1| 135|Homo sapiens protein.
Length = 135
Score = 35.1 bits (77), Expect = 0.19
Identities = 15/25 (60%), Positives = 20/25 (80%)
Frame = +3
Query: 3 DPELFNLITKEKKRQQAGLEMIASE 77
DPE++ L+ +EK RQ GLE+IASE
Sbjct: 53 DPEMWELLQREKDRQCRGLELIASE 77
Database: human
Posted date: Oct 23, 2007 1:18 PM
Number of letters in database: 76,859,062
Number of sequences in database: 237,096
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 85,785,254
Number of Sequences: 237096
Number of extensions: 1851934
Number of successful extensions: 3952
Number of sequences better than 10.0: 22
Number of HSP's better than 10.0 without gapping: 3842
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 3951
length of database: 76,859,062
effective HSP length: 86
effective length of database: 56,468,806
effective search space used: 6324506272
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
- SilkBase 1999-2023 -