Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= I10A02NGRL0007_G02
(603 letters)
Database: human
237,096 sequences; 76,859,062 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
CR541695-1|CAG46496.1| 414|Homo sapiens IDH1 protein. 312 5e-85
CR536499-1|CAG38738.1| 414|Homo sapiens IDH1 protein. 312 5e-85
BC093020-1|AAH93020.1| 414|Homo sapiens isocitrate dehydrogenas... 312 5e-85
BC012846-1|AAH12846.1| 414|Homo sapiens IDH1 protein protein. 312 5e-85
AF113917-1|AAD29284.1| 414|Homo sapiens NADP+-dependent isocitr... 312 5e-85
AC016697-3|AAX93221.1| 414|Homo sapiens unknown protein. 312 5e-85
AF020038-1|AAD02918.1| 414|Homo sapiens NADP-dependent isocitra... 310 2e-84
BX537411-1|CAD97653.1| 414|Homo sapiens hypothetical protein pr... 309 4e-84
CR533522-1|CAG38553.1| 414|Homo sapiens IDH1 protein. 308 8e-84
X69433-1|CAA49208.1| 452|Homo sapiens isocitrate dehydrogenase... 305 5e-83
BC071828-1|AAH71828.1| 452|Homo sapiens isocitrate dehydrogenas... 305 5e-83
BC009244-1|AAH09244.1| 452|Homo sapiens isocitrate dehydrogenas... 305 5e-83
AK222916-1|BAD96636.1| 452|Homo sapiens isocitrate dehydrogenas... 305 5e-83
DQ403082-1|ABD77215.1| 371|Homo sapiens isocitrate dehydrogenas... 298 8e-81
U52144-1|AAC50455.1| 419|Homo sapiens isocitrate dehydrogenase ... 281 1e-75
U62389-1|AAB17375.1| 154|Homo sapiens putative cytosolic NADP-d... 180 5e-45
AK090454-1|BAC03435.1| 708|Homo sapiens FLJ00375 protein protein. 33 0.77
AY251274-1|AAP04412.1| 291|Homo sapiens unknown protein. 31 4.1
AK024496-1|BAB15786.1| 287|Homo sapiens FLJ00104 protein protein. 31 4.1
BC065822-1|AAH65822.1| 323|Homo sapiens zinc finger protein 784... 30 5.4
AK074859-1|BAC11251.1| 323|Homo sapiens protein ( Homo sapiens ... 30 5.4
U25975-1|AAA75468.1| 493|Homo sapiens hPAK65 protein. 30 7.2
U24153-1|AAA65442.1| 525|Homo sapiens p21-activated protein kin... 30 7.2
BC107058-1|AAI07059.1| 292|Homo sapiens snail homolog 3 (Drosop... 30 7.2
BC069613-1|AAH69613.1| 524|Homo sapiens p21-activated kinase 2 ... 30 7.2
BC041461-1|AAH41461.1| 283|Homo sapiens Similar to snail homolo... 30 7.2
AB209428-1|BAD92665.1| 279|Homo sapiens p21-activated kinase 2 ... 30 7.2
BC067854-1|AAH67854.1| 503|Homo sapiens CPAMD8 protein protein. 29 9.5
AY101765-1|AAM50084.1| 1885|Homo sapiens C3 and PZP-like alpha-2... 29 9.5
AB033109-1|BAA86597.1| 1884|Homo sapiens KIAA1283 protein protein. 29 9.5
>CR541695-1|CAG46496.1| 414|Homo sapiens IDH1 protein.
Length = 414
Score = 312 bits (767), Expect = 5e-85
Identities = 147/202 (72%), Positives = 170/202 (84%), Gaps = 2/202 (0%)
Frame = +2
Query: 2 IIWAKIKEKLIFPYVKLDCLYYDLGLPHRDATDDQVTIDAAHAILKHNVGIKCATITPDE 181
IIW IKEKLIFPYV+LD YDLG+ +RDAT+DQVT DAA AI KHNVG+KCATITPDE
Sbjct: 21 IIWELIKEKLIFPYVELDLHSYDLGIENRDATNDQVTKDAAEAIKKHNVGVKCATITPDE 80
Query: 182 QRVEEFKLKKMWLSPNGTIRNILGGTVFREPILCKSIPRVVPGWTKAIVIGRHAHGDQYK 361
+RVEEFKLK+MW SPNGTIRNILGGTVFRE I+CK+IPR+V GW K I+IGRHA+GDQY+
Sbjct: 81 KRVEEFKLKQMWKSPNGTIRNILGGTVFREAIICKNIPRLVSGWVKPIIIGRHAYGDQYR 140
Query: 362 AQDFVVPKPGKVELVYTAEDGTTE-KRLLYDFKT-PGVVLGMYNIDESIRAFAHSSFQVA 535
A DFVVP PGKVE+ YT DGT + L+++F+ GV +GMYN D+SI FAHSSFQ+A
Sbjct: 141 ATDFVVPGPGKVEITYTPSDGTQKVTYLVHNFEEGGGVAMGMYNQDKSIEDFAHSSFQMA 200
Query: 536 LQKKWPLYLSTKNTILKRYDGR 601
L K WPLYLSTKNTILK+YDGR
Sbjct: 201 LSKGWPLYLSTKNTILKKYDGR 222
>CR536499-1|CAG38738.1| 414|Homo sapiens IDH1 protein.
Length = 414
Score = 312 bits (767), Expect = 5e-85
Identities = 147/202 (72%), Positives = 170/202 (84%), Gaps = 2/202 (0%)
Frame = +2
Query: 2 IIWAKIKEKLIFPYVKLDCLYYDLGLPHRDATDDQVTIDAAHAILKHNVGIKCATITPDE 181
IIW IKEKLIFPYV+LD YDLG+ +RDAT+DQVT DAA AI KHNVG+KCATITPDE
Sbjct: 21 IIWELIKEKLIFPYVELDLHSYDLGIENRDATNDQVTKDAAEAIKKHNVGVKCATITPDE 80
Query: 182 QRVEEFKLKKMWLSPNGTIRNILGGTVFREPILCKSIPRVVPGWTKAIVIGRHAHGDQYK 361
+RVEEFKLK+MW SPNGTIRNILGGTVFRE I+CK+IPR+V GW K I+IGRHA+GDQY+
Sbjct: 81 KRVEEFKLKQMWKSPNGTIRNILGGTVFREAIICKNIPRLVSGWVKPIIIGRHAYGDQYR 140
Query: 362 AQDFVVPKPGKVELVYTAEDGTTE-KRLLYDFKT-PGVVLGMYNIDESIRAFAHSSFQVA 535
A DFVVP PGKVE+ YT DGT + L+++F+ GV +GMYN D+SI FAHSSFQ+A
Sbjct: 141 ATDFVVPGPGKVEMTYTPSDGTQKVTYLVHNFEEGGGVAMGMYNQDKSIEDFAHSSFQMA 200
Query: 536 LQKKWPLYLSTKNTILKRYDGR 601
L K WPLYLSTKNTILK+YDGR
Sbjct: 201 LSKGWPLYLSTKNTILKKYDGR 222
>BC093020-1|AAH93020.1| 414|Homo sapiens isocitrate dehydrogenase 1
(NADP+), soluble protein.
Length = 414
Score = 312 bits (767), Expect = 5e-85
Identities = 147/202 (72%), Positives = 170/202 (84%), Gaps = 2/202 (0%)
Frame = +2
Query: 2 IIWAKIKEKLIFPYVKLDCLYYDLGLPHRDATDDQVTIDAAHAILKHNVGIKCATITPDE 181
IIW IKEKLIFPYV+LD YDLG+ +RDAT+DQVT DAA AI KHNVG+KCATITPDE
Sbjct: 21 IIWELIKEKLIFPYVELDLHSYDLGIENRDATNDQVTKDAAEAIKKHNVGVKCATITPDE 80
Query: 182 QRVEEFKLKKMWLSPNGTIRNILGGTVFREPILCKSIPRVVPGWTKAIVIGRHAHGDQYK 361
+RVEEFKLK+MW SPNGTIRNILGGTVFRE I+CK+IPR+V GW K I+IGRHA+GDQY+
Sbjct: 81 KRVEEFKLKQMWKSPNGTIRNILGGTVFREAIICKNIPRLVSGWVKPIIIGRHAYGDQYR 140
Query: 362 AQDFVVPKPGKVELVYTAEDGTTE-KRLLYDFKT-PGVVLGMYNIDESIRAFAHSSFQVA 535
A DFVVP PGKVE+ YT DGT + L+++F+ GV +GMYN D+SI FAHSSFQ+A
Sbjct: 141 ATDFVVPGPGKVEITYTPSDGTQKVTYLVHNFEEGGGVAMGMYNQDKSIEDFAHSSFQMA 200
Query: 536 LQKKWPLYLSTKNTILKRYDGR 601
L K WPLYLSTKNTILK+YDGR
Sbjct: 201 LSKGWPLYLSTKNTILKKYDGR 222
>BC012846-1|AAH12846.1| 414|Homo sapiens IDH1 protein protein.
Length = 414
Score = 312 bits (767), Expect = 5e-85
Identities = 147/202 (72%), Positives = 170/202 (84%), Gaps = 2/202 (0%)
Frame = +2
Query: 2 IIWAKIKEKLIFPYVKLDCLYYDLGLPHRDATDDQVTIDAAHAILKHNVGIKCATITPDE 181
IIW IKEKLIFPYV+LD YDLG+ +RDAT+DQVT DAA AI KHNVG+KCATITPDE
Sbjct: 21 IIWELIKEKLIFPYVELDLHSYDLGIENRDATNDQVTKDAAEAIKKHNVGVKCATITPDE 80
Query: 182 QRVEEFKLKKMWLSPNGTIRNILGGTVFREPILCKSIPRVVPGWTKAIVIGRHAHGDQYK 361
+RVEEFKLK+MW SPNGTIRNILGGTVFRE I+CK+IPR+V GW K I+IGRHA+GDQY+
Sbjct: 81 KRVEEFKLKQMWKSPNGTIRNILGGTVFREAIICKNIPRLVSGWVKPIIIGRHAYGDQYR 140
Query: 362 AQDFVVPKPGKVELVYTAEDGTTE-KRLLYDFKT-PGVVLGMYNIDESIRAFAHSSFQVA 535
A DFVVP PGKVE+ YT DGT + L+++F+ GV +GMYN D+SI FAHSSFQ+A
Sbjct: 141 ATDFVVPGPGKVEITYTPSDGTQKVTYLVHNFEEGGGVAMGMYNQDKSIEDFAHSSFQMA 200
Query: 536 LQKKWPLYLSTKNTILKRYDGR 601
L K WPLYLSTKNTILK+YDGR
Sbjct: 201 LSKGWPLYLSTKNTILKKYDGR 222
>AF113917-1|AAD29284.1| 414|Homo sapiens NADP+-dependent isocitrate
dehydrogenase protein.
Length = 414
Score = 312 bits (767), Expect = 5e-85
Identities = 147/202 (72%), Positives = 170/202 (84%), Gaps = 2/202 (0%)
Frame = +2
Query: 2 IIWAKIKEKLIFPYVKLDCLYYDLGLPHRDATDDQVTIDAAHAILKHNVGIKCATITPDE 181
IIW IKEKLIFPYV+LD YDLG+ +RDAT+DQVT DAA AI KHNVG+KCATITPDE
Sbjct: 21 IIWELIKEKLIFPYVELDLHSYDLGIENRDATNDQVTKDAAEAIKKHNVGVKCATITPDE 80
Query: 182 QRVEEFKLKKMWLSPNGTIRNILGGTVFREPILCKSIPRVVPGWTKAIVIGRHAHGDQYK 361
+RVEEFKLK+MW SPNGTIRNILGGTVFRE I+CK+IPR+V GW K I+IGRHA+GDQY+
Sbjct: 81 KRVEEFKLKQMWKSPNGTIRNILGGTVFREAIICKNIPRLVSGWVKPIIIGRHAYGDQYR 140
Query: 362 AQDFVVPKPGKVELVYTAEDGTTE-KRLLYDFKT-PGVVLGMYNIDESIRAFAHSSFQVA 535
A DFVVP PGKVE+ YT DGT + L+++F+ GV +GMYN D+SI FAHSSFQ+A
Sbjct: 141 ATDFVVPGPGKVEITYTPSDGTQKVTYLVHNFEEGGGVAMGMYNQDKSIEDFAHSSFQMA 200
Query: 536 LQKKWPLYLSTKNTILKRYDGR 601
L K WPLYLSTKNTILK+YDGR
Sbjct: 201 LSKGWPLYLSTKNTILKKYDGR 222
>AC016697-3|AAX93221.1| 414|Homo sapiens unknown protein.
Length = 414
Score = 312 bits (767), Expect = 5e-85
Identities = 147/202 (72%), Positives = 170/202 (84%), Gaps = 2/202 (0%)
Frame = +2
Query: 2 IIWAKIKEKLIFPYVKLDCLYYDLGLPHRDATDDQVTIDAAHAILKHNVGIKCATITPDE 181
IIW IKEKLIFPYV+LD YDLG+ +RDAT+DQVT DAA AI KHNVG+KCATITPDE
Sbjct: 21 IIWELIKEKLIFPYVELDLHSYDLGIENRDATNDQVTKDAAEAIKKHNVGVKCATITPDE 80
Query: 182 QRVEEFKLKKMWLSPNGTIRNILGGTVFREPILCKSIPRVVPGWTKAIVIGRHAHGDQYK 361
+RVEEFKLK+MW SPNGTIRNILGGTVFRE I+CK+IPR+V GW K I+IGRHA+GDQY+
Sbjct: 81 KRVEEFKLKQMWKSPNGTIRNILGGTVFREAIICKNIPRLVSGWVKPIIIGRHAYGDQYR 140
Query: 362 AQDFVVPKPGKVELVYTAEDGTTE-KRLLYDFKT-PGVVLGMYNIDESIRAFAHSSFQVA 535
A DFVVP PGKVE+ YT DGT + L+++F+ GV +GMYN D+SI FAHSSFQ+A
Sbjct: 141 ATDFVVPGPGKVEITYTPSDGTQKVTYLVHNFEEGGGVAMGMYNQDKSIEDFAHSSFQMA 200
Query: 536 LQKKWPLYLSTKNTILKRYDGR 601
L K WPLYLSTKNTILK+YDGR
Sbjct: 201 LSKGWPLYLSTKNTILKKYDGR 222
>AF020038-1|AAD02918.1| 414|Homo sapiens NADP-dependent isocitrate
dehydrogenase protein.
Length = 414
Score = 310 bits (762), Expect = 2e-84
Identities = 147/202 (72%), Positives = 169/202 (83%), Gaps = 2/202 (0%)
Frame = +2
Query: 2 IIWAKIKEKLIFPYVKLDCLYYDLGLPHRDATDDQVTIDAAHAILKHNVGIKCATITPDE 181
IIW IKEKLIFPYV+LD YDLG+ +RDAT+DQVT DAA AI KHNVG+KCATITPDE
Sbjct: 21 IIWELIKEKLIFPYVELDLHSYDLGIENRDATNDQVTKDAAEAIKKHNVGVKCATITPDE 80
Query: 182 QRVEEFKLKKMWLSPNGTIRNILGGTVFREPILCKSIPRVVPGWTKAIVIGRHAHGDQYK 361
+RVEEFKLK+MW SPNGTIRNILGGTVFRE I+CK+IPR+V GW K I+IGRHA+GDQY+
Sbjct: 81 KRVEEFKLKQMWKSPNGTIRNILGGTVFREAIICKNIPRLVSGWVKPIIIGRHAYGDQYR 140
Query: 362 AQDFVVPKPGKVELVYTAEDGTTE-KRLLYDFKT-PGVVLGMYNIDESIRAFAHSSFQVA 535
A DFVVP PGKVE+ YT DGT + L+++F+ GV +GMYN D+SI FAHSSFQ+A
Sbjct: 141 ATDFVVPGPGKVEITYTPSDGTQKVTYLVHNFEEGGGVAMGMYNQDKSIEDFAHSSFQMA 200
Query: 536 LQKKWPLYLSTKNTILKRYDGR 601
L K WPLYLSTKNTILK YDGR
Sbjct: 201 LSKGWPLYLSTKNTILKIYDGR 222
>BX537411-1|CAD97653.1| 414|Homo sapiens hypothetical protein
protein.
Length = 414
Score = 309 bits (759), Expect = 4e-84
Identities = 146/202 (72%), Positives = 165/202 (81%), Gaps = 2/202 (0%)
Frame = +2
Query: 2 IIWAKIKEKLIFPYVKLDCLYYDLGLPHRDATDDQVTIDAAHAILKHNVGIKCATITPDE 181
IIW IKEKLIFPYV+LD YDLG+ +RDAT+DQVT DAA AI KHNVG+KCATITPDE
Sbjct: 21 IIWELIKEKLIFPYVELDLHSYDLGIENRDATNDQVTKDAAEAIKKHNVGVKCATITPDE 80
Query: 182 QRVEEFKLKKMWLSPNGTIRNILGGTVFREPILCKSIPRVVPGWTKAIVIGRHAHGDQYK 361
+RVEEFKLK+MW SPNGTIRNILGGTVFRE I+CK+IPR+V GW K I+IGRHA+GDQY+
Sbjct: 81 KRVEEFKLKQMWKSPNGTIRNILGGTVFREAIICKNIPRLVSGWVKPIIIGRHAYGDQYR 140
Query: 362 AQDFVVPKPGKVELVYTAEDGTTEKRLLYDFKT--PGVVLGMYNIDESIRAFAHSSFQVA 535
A DFVVP PGKVE+ YT DGT + L GV +GMYN D+SI FAHSSFQ+A
Sbjct: 141 ATDFVVPGPGKVEITYTPSDGTQKVTYLVHNSEGGGGVAMGMYNQDKSIEDFAHSSFQMA 200
Query: 536 LQKKWPLYLSTKNTILKRYDGR 601
L K WPLYLSTKNTILK+YDGR
Sbjct: 201 LSKGWPLYLSTKNTILKKYDGR 222
>CR533522-1|CAG38553.1| 414|Homo sapiens IDH1 protein.
Length = 414
Score = 308 bits (757), Expect = 8e-84
Identities = 145/202 (71%), Positives = 169/202 (83%), Gaps = 2/202 (0%)
Frame = +2
Query: 2 IIWAKIKEKLIFPYVKLDCLYYDLGLPHRDATDDQVTIDAAHAILKHNVGIKCATITPDE 181
IIW IKEKLI PYV+LD YDLG+ +RDAT+DQVT DAA AI KHNVG+KCATITPDE
Sbjct: 21 IIWELIKEKLIIPYVELDLHSYDLGIENRDATNDQVTKDAAEAIKKHNVGVKCATITPDE 80
Query: 182 QRVEEFKLKKMWLSPNGTIRNILGGTVFREPILCKSIPRVVPGWTKAIVIGRHAHGDQYK 361
+RVEEFKLK+MW SPNGTIRNILGGTVFRE I+CK+IPR+V GW + I+IGRHA+GDQY+
Sbjct: 81 KRVEEFKLKQMWKSPNGTIRNILGGTVFREAIICKNIPRLVSGWVEPIIIGRHAYGDQYR 140
Query: 362 AQDFVVPKPGKVELVYTAEDGTTE-KRLLYDFKT-PGVVLGMYNIDESIRAFAHSSFQVA 535
A DFVVP PGKVE+ YT DGT + L+++F+ GV +GMYN D+SI FAHSSFQ+A
Sbjct: 141 ATDFVVPGPGKVEITYTPSDGTQKVTYLVHNFEEGGGVAMGMYNQDKSIEDFAHSSFQMA 200
Query: 536 LQKKWPLYLSTKNTILKRYDGR 601
L K WPLYLSTKNTILK+YDGR
Sbjct: 201 LSKGWPLYLSTKNTILKKYDGR 222
>X69433-1|CAA49208.1| 452|Homo sapiens isocitrate dehydrogenase
(NADP+) protein.
Length = 452
Score = 305 bits (750), Expect = 5e-83
Identities = 141/201 (70%), Positives = 163/201 (81%), Gaps = 1/201 (0%)
Frame = +2
Query: 2 IIWAKIKEKLIFPYVKLDCLYYDLGLPHRDATDDQVTIDAAHAILKHNVGIKCATITPDE 181
IIW IKEKLI P+V + Y+DLGLP+RD TDDQVTID+A A K++V +KCATITPDE
Sbjct: 61 IIWQFIKEKLILPHVDIQLKYFDLGLPNRDQTDDQVTIDSALATQKYSVAVKCATITPDE 120
Query: 182 QRVEEFKLKKMWLSPNGTIRNILGGTVFREPILCKSIPRVVPGWTKAIVIGRHAHGDQYK 361
RVEEFKLKKMW SPNGTIRNILGGTVFREPI+CK+IPR+VPGWTK I IGRHAHGDQYK
Sbjct: 121 ARVEEFKLKKMWKSPNGTIRNILGGTVFREPIICKNIPRLVPGWTKPITIGRHAHGDQYK 180
Query: 362 AQDFVVPKPGKVELVYTAEDGTTEKRL-LYDFKTPGVVLGMYNIDESIRAFAHSSFQVAL 538
A DFV + G ++V+T +DG+ K +Y+F GV +GMYN DESI FAHS FQ A+
Sbjct: 181 ATDFVADRAGTFKMVFTPKDGSGVKEWEVYNFPAGGVGMGMYNTDESISGFAHSCFQYAI 240
Query: 539 QKKWPLYLSTKNTILKRYDGR 601
QKKWPLY+STKNTILK YDGR
Sbjct: 241 QKKWPLYMSTKNTILKAYDGR 261
>BC071828-1|AAH71828.1| 452|Homo sapiens isocitrate dehydrogenase 2
(NADP+), mitochondrial protein.
Length = 452
Score = 305 bits (750), Expect = 5e-83
Identities = 141/201 (70%), Positives = 163/201 (81%), Gaps = 1/201 (0%)
Frame = +2
Query: 2 IIWAKIKEKLIFPYVKLDCLYYDLGLPHRDATDDQVTIDAAHAILKHNVGIKCATITPDE 181
IIW IKEKLI P+V + Y+DLGLP+RD TDDQVTID+A A K++V +KCATITPDE
Sbjct: 61 IIWQFIKEKLILPHVDIQLKYFDLGLPNRDQTDDQVTIDSALATQKYSVAVKCATITPDE 120
Query: 182 QRVEEFKLKKMWLSPNGTIRNILGGTVFREPILCKSIPRVVPGWTKAIVIGRHAHGDQYK 361
RVEEFKLKKMW SPNGTIRNILGGTVFREPI+CK+IPR+VPGWTK I IGRHAHGDQYK
Sbjct: 121 ARVEEFKLKKMWKSPNGTIRNILGGTVFREPIICKNIPRLVPGWTKPITIGRHAHGDQYK 180
Query: 362 AQDFVVPKPGKVELVYTAEDGTTEKRL-LYDFKTPGVVLGMYNIDESIRAFAHSSFQVAL 538
A DFV + G ++V+T +DG+ K +Y+F GV +GMYN DESI FAHS FQ A+
Sbjct: 181 ATDFVADRAGTFKMVFTPKDGSGVKEWEVYNFPAGGVGMGMYNTDESISGFAHSCFQYAI 240
Query: 539 QKKWPLYLSTKNTILKRYDGR 601
QKKWPLY+STKNTILK YDGR
Sbjct: 241 QKKWPLYMSTKNTILKAYDGR 261
>BC009244-1|AAH09244.1| 452|Homo sapiens isocitrate dehydrogenase 2
(NADP+), mitochondrial protein.
Length = 452
Score = 305 bits (750), Expect = 5e-83
Identities = 141/201 (70%), Positives = 163/201 (81%), Gaps = 1/201 (0%)
Frame = +2
Query: 2 IIWAKIKEKLIFPYVKLDCLYYDLGLPHRDATDDQVTIDAAHAILKHNVGIKCATITPDE 181
IIW IKEKLI P+V + Y+DLGLP+RD TDDQVTID+A A K++V +KCATITPDE
Sbjct: 61 IIWQFIKEKLILPHVDIQLKYFDLGLPNRDQTDDQVTIDSALATQKYSVAVKCATITPDE 120
Query: 182 QRVEEFKLKKMWLSPNGTIRNILGGTVFREPILCKSIPRVVPGWTKAIVIGRHAHGDQYK 361
RVEEFKLKKMW SPNGTIRNILGGTVFREPI+CK+IPR+VPGWTK I IGRHAHGDQYK
Sbjct: 121 ARVEEFKLKKMWKSPNGTIRNILGGTVFREPIICKNIPRLVPGWTKPITIGRHAHGDQYK 180
Query: 362 AQDFVVPKPGKVELVYTAEDGTTEKRL-LYDFKTPGVVLGMYNIDESIRAFAHSSFQVAL 538
A DFV + G ++V+T +DG+ K +Y+F GV +GMYN DESI FAHS FQ A+
Sbjct: 181 ATDFVADRAGTFKMVFTPKDGSGVKEWEVYNFPAGGVGMGMYNTDESISGFAHSCFQYAI 240
Query: 539 QKKWPLYLSTKNTILKRYDGR 601
QKKWPLY+STKNTILK YDGR
Sbjct: 241 QKKWPLYMSTKNTILKAYDGR 261
>AK222916-1|BAD96636.1| 452|Homo sapiens isocitrate dehydrogenase 2
(NADP+), mitochondrial precursor variant protein.
Length = 452
Score = 305 bits (750), Expect = 5e-83
Identities = 141/201 (70%), Positives = 163/201 (81%), Gaps = 1/201 (0%)
Frame = +2
Query: 2 IIWAKIKEKLIFPYVKLDCLYYDLGLPHRDATDDQVTIDAAHAILKHNVGIKCATITPDE 181
IIW IKEKLI P+V + Y+DLGLP+RD TDDQVTID+A A K++V +KCATITPDE
Sbjct: 61 IIWQFIKEKLILPHVDIQLKYFDLGLPNRDQTDDQVTIDSALATQKYSVAVKCATITPDE 120
Query: 182 QRVEEFKLKKMWLSPNGTIRNILGGTVFREPILCKSIPRVVPGWTKAIVIGRHAHGDQYK 361
RVEEFKLKKMW SPNGTIRNILGGTVFREPI+CK+IPR+VPGWTK I IGRHAHGDQYK
Sbjct: 121 ARVEEFKLKKMWKSPNGTIRNILGGTVFREPIICKNIPRLVPGWTKPITIGRHAHGDQYK 180
Query: 362 AQDFVVPKPGKVELVYTAEDGTTEKRL-LYDFKTPGVVLGMYNIDESIRAFAHSSFQVAL 538
A DFV + G ++V+T +DG+ K +Y+F GV +GMYN DESI FAHS FQ A+
Sbjct: 181 ATDFVADRAGTFKMVFTPKDGSGVKEWEVYNFPAGGVGMGMYNTDESISGFAHSCFQYAI 240
Query: 539 QKKWPLYLSTKNTILKRYDGR 601
QKKWPLY+STKNTILK YDGR
Sbjct: 241 QKKWPLYMSTKNTILKAYDGR 261
>DQ403082-1|ABD77215.1| 371|Homo sapiens isocitrate dehydrogenase 1
protein.
Length = 371
Score = 298 bits (732), Expect = 8e-81
Identities = 140/193 (72%), Positives = 163/193 (84%), Gaps = 2/193 (1%)
Frame = +2
Query: 29 LIFPYVKLDCLYYDLGLPHRDATDDQVTIDAAHAILKHNVGIKCATITPDEQRVEEFKLK 208
LIFPYV+LD YDLG+ +RDAT+DQVT DAA AI KHNVG+KCATITPDE+RVEEFKLK
Sbjct: 1 LIFPYVELDLHSYDLGIENRDATNDQVTKDAAEAIKKHNVGVKCATITPDEKRVEEFKLK 60
Query: 209 KMWLSPNGTIRNILGGTVFREPILCKSIPRVVPGWTKAIVIGRHAHGDQYKAQDFVVPKP 388
+MW SPNGTIRNILGGTVFRE I+CK+IPR+V GW K I+IGRHA+GDQY+A DFVVP P
Sbjct: 61 QMWKSPNGTIRNILGGTVFREAIICKNIPRLVSGWVKPIIIGRHAYGDQYRATDFVVPGP 120
Query: 389 GKVELVYTAEDGTTE-KRLLYDFKT-PGVVLGMYNIDESIRAFAHSSFQVALQKKWPLYL 562
GKVE+ YT DGT + L+++F+ GV +GMYN D+SI FAHSSFQ+AL K WPLYL
Sbjct: 121 GKVEITYTPSDGTQKVTYLVHNFEEGGGVAMGMYNQDKSIEDFAHSSFQMALSKGWPLYL 180
Query: 563 STKNTILKRYDGR 601
STKNTILK+YDGR
Sbjct: 181 STKNTILKKYDGR 193
>U52144-1|AAC50455.1| 419|Homo sapiens isocitrate dehydrogenase
protein.
Length = 419
Score = 281 bits (690), Expect = 1e-75
Identities = 129/181 (71%), Positives = 149/181 (82%), Gaps = 1/181 (0%)
Frame = +2
Query: 62 YYDLGLPHRDATDDQVTIDAAHAILKHNVGIKCATITPDEQRVEEFKLKKMWLSPNGTIR 241
Y+DLGLP+RD TDDQVTID+A A K++V +KCATITPDE RVEEFKLKKMW SPNGTIR
Sbjct: 48 YFDLGLPNRDQTDDQVTIDSALATQKYSVAVKCATITPDEARVEEFKLKKMWKSPNGTIR 107
Query: 242 NILGGTVFREPILCKSIPRVVPGWTKAIVIGRHAHGDQYKAQDFVVPKPGKVELVYTAED 421
NI GGTVFREPI+CK+IPR+VPGWTK I IGRHAHGDQYKA DFV + G ++V+T +D
Sbjct: 108 NIHGGTVFREPIICKNIPRLVPGWTKPITIGRHAHGDQYKATDFVADRAGTFKMVFTPKD 167
Query: 422 GTTEKRL-LYDFKTPGVVLGMYNIDESIRAFAHSSFQVALQKKWPLYLSTKNTILKRYDG 598
G+ K +Y+F GV +GMYN DESI FAHS FQ A+QKKWPLY+STKNTILK YDG
Sbjct: 168 GSGVKEWEVYNFPAGGVGMGMYNTDESISGFAHSCFQYAIQKKWPLYMSTKNTILKAYDG 227
Query: 599 R 601
R
Sbjct: 228 R 228
>U62389-1|AAB17375.1| 154|Homo sapiens putative cytosolic
NADP-dependent isocitrate dehydrogenase protein.
Length = 154
Score = 180 bits (437), Expect = 5e-45
Identities = 84/123 (68%), Positives = 100/123 (81%), Gaps = 2/123 (1%)
Frame = +2
Query: 239 RNILGGTVFREPILCKSIPRVVPGWTKAIVIGRHAHGDQYKAQDFVVPKPGKVELVYTAE 418
RNILGGTVF E I+CK+IPR+V GW K I+IGRHA+GDQY+A DFVVP PGKVE+ YT
Sbjct: 1 RNILGGTVFXEAIICKNIPRLVSGWVKPIIIGRHAYGDQYRATDFVVPGPGKVEITYTPS 60
Query: 419 DGTTE-KRLLYDFKT-PGVVLGMYNIDESIRAFAHSSFQVALQKKWPLYLSTKNTILKRY 592
DGT + L+++F+ GV +GMYN D+SI FAHSSFQ+AL K WPLYLSTKNTILK+Y
Sbjct: 61 DGTQKVTYLVHNFEEGGGVAMGMYNQDKSIEDFAHSSFQMALSKGWPLYLSTKNTILKKY 120
Query: 593 DGR 601
DGR
Sbjct: 121 DGR 123
>AK090454-1|BAC03435.1| 708|Homo sapiens FLJ00375 protein protein.
Length = 708
Score = 33.1 bits (72), Expect = 0.77
Identities = 15/43 (34%), Positives = 20/43 (46%)
Frame = +2
Query: 293 PRVVPGWTKAIVIGRHAHGDQYKAQDFVVPKPGKVELVYTAED 421
PR GW + + H H DQ +P PGK +L+ A D
Sbjct: 20 PRAFKGWARPWLAQCHLHADQQPRAMHRMPDPGKFKLLEQARD 62
>AY251274-1|AAP04412.1| 291|Homo sapiens unknown protein.
Length = 291
Score = 30.7 bits (66), Expect = 4.1
Identities = 21/61 (34%), Positives = 26/61 (42%)
Frame = -1
Query: 402 SSTFPGFGTTKSCALY*SPCA*RPITMALVHPGTTLGILLHSMGSRNTVPPRMLRIVPFG 223
S FPG+G AL PC RP A HP ++L + R T PP +G
Sbjct: 29 SRGFPGWGCRTGQAL---PCRARPPAPAPSHPSSSLSLTPGPGSPRQTGPPCQTVAALYG 85
Query: 222 L 220
L
Sbjct: 86 L 86
>AK024496-1|BAB15786.1| 287|Homo sapiens FLJ00104 protein protein.
Length = 287
Score = 30.7 bits (66), Expect = 4.1
Identities = 21/61 (34%), Positives = 26/61 (42%)
Frame = -1
Query: 402 SSTFPGFGTTKSCALY*SPCA*RPITMALVHPGTTLGILLHSMGSRNTVPPRMLRIVPFG 223
S FPG+G AL PC RP A HP ++L + R T PP +G
Sbjct: 25 SRGFPGWGCRTGQAL---PCRARPPAPAPSHPSSSLSLTPGPGSPRQTGPPCQTVAALYG 81
Query: 222 L 220
L
Sbjct: 82 L 82
>BC065822-1|AAH65822.1| 323|Homo sapiens zinc finger protein 784
protein.
Length = 323
Score = 30.3 bits (65), Expect = 5.4
Identities = 13/37 (35%), Positives = 19/37 (51%)
Frame = -3
Query: 541 LQGHLETRMGKRPYRFVYIVHAQNNAGSFKIVQKTFF 431
L GH G+RP+R NN+ +F+ Q+T F
Sbjct: 239 LSGHARIHTGERPFRCTLCDRTFNNSSNFRKHQRTHF 275
>AK074859-1|BAC11251.1| 323|Homo sapiens protein ( Homo sapiens
cDNA FLJ90378 fis, clone NT2RP2004847, weakly similar to
ZINC FINGER PROTEIN 135. ).
Length = 323
Score = 30.3 bits (65), Expect = 5.4
Identities = 13/37 (35%), Positives = 19/37 (51%)
Frame = -3
Query: 541 LQGHLETRMGKRPYRFVYIVHAQNNAGSFKIVQKTFF 431
L GH G+RP+R NN+ +F+ Q+T F
Sbjct: 239 LSGHARIHTGERPFRCTLCDRTFNNSSNFRKHQRTHF 275
>U25975-1|AAA75468.1| 493|Homo sapiens hPAK65 protein.
Length = 493
Score = 29.9 bits (64), Expect = 7.2
Identities = 16/60 (26%), Positives = 25/60 (41%)
Frame = +2
Query: 83 HRDATDDQVTIDAAHAILKHNVGIKCATITPDEQRVEEFKLKKMWLSPNGTIRNILGGTV 262
HRD D V + ++ + G CA ITP++ + W++P R G V
Sbjct: 335 HRDIKSDNVLLGMEGSVKLTDFGF-CAQITPEQSKRSTMVGTPYWMAPEVVTRKAYGPKV 393
>U24153-1|AAA65442.1| 525|Homo sapiens p21-activated protein kinase
protein.
Length = 525
Score = 29.9 bits (64), Expect = 7.2
Identities = 16/60 (26%), Positives = 25/60 (41%)
Frame = +2
Query: 83 HRDATDDQVTIDAAHAILKHNVGIKCATITPDEQRVEEFKLKKMWLSPNGTIRNILGGTV 262
HRD D V + ++ + G CA ITP++ + W++P R G V
Sbjct: 367 HRDIKSDNVLLGMEGSVKLTDFGF-CAQITPEQSKRSTMVGTPYWMAPEVVTRKAYGPKV 425
>BC107058-1|AAI07059.1| 292|Homo sapiens snail homolog 3
(Drosophila) protein.
Length = 292
Score = 29.9 bits (64), Expect = 7.2
Identities = 10/18 (55%), Positives = 14/18 (77%)
Frame = -3
Query: 553 RPFFLQGHLETRMGKRPY 500
RP+ LQGH+ T G++PY
Sbjct: 220 RPWLLQGHVRTHTGEKPY 237
>BC069613-1|AAH69613.1| 524|Homo sapiens p21-activated kinase 2
protein.
Length = 524
Score = 29.9 bits (64), Expect = 7.2
Identities = 16/60 (26%), Positives = 25/60 (41%)
Frame = +2
Query: 83 HRDATDDQVTIDAAHAILKHNVGIKCATITPDEQRVEEFKLKKMWLSPNGTIRNILGGTV 262
HRD D V + ++ + G CA ITP++ + W++P R G V
Sbjct: 366 HRDIKSDNVLLGMEGSVKLTDFGF-CAQITPEQSKRSTMVGTPYWMAPEVVTRKAYGPKV 424
>BC041461-1|AAH41461.1| 283|Homo sapiens Similar to snail homolog 3
(Drosophila) protein.
Length = 283
Score = 29.9 bits (64), Expect = 7.2
Identities = 10/18 (55%), Positives = 14/18 (77%)
Frame = -3
Query: 553 RPFFLQGHLETRMGKRPY 500
RP+ LQGH+ T G++PY
Sbjct: 211 RPWLLQGHVRTHTGEKPY 228
>AB209428-1|BAD92665.1| 279|Homo sapiens p21-activated kinase 2
variant protein.
Length = 279
Score = 29.9 bits (64), Expect = 7.2
Identities = 16/60 (26%), Positives = 25/60 (41%)
Frame = +2
Query: 83 HRDATDDQVTIDAAHAILKHNVGIKCATITPDEQRVEEFKLKKMWLSPNGTIRNILGGTV 262
HRD D V + ++ + G CA ITP++ + W++P R G V
Sbjct: 124 HRDIKSDSVLLGMEGSVKLTDFGF-CAQITPEQSKRSTVIRTPYWMAPEVVTRKAYGPKV 182
>BC067854-1|AAH67854.1| 503|Homo sapiens CPAMD8 protein protein.
Length = 503
Score = 29.5 bits (63), Expect = 9.5
Identities = 39/147 (26%), Positives = 64/147 (43%), Gaps = 15/147 (10%)
Frame = +2
Query: 137 KHNVGIKCATITPDEQRVEEFKLKKMWLSPNGTIRNILGGTVFREPILC----KSIPR-- 298
+H V I T++P+ + V E KL+ L P G+ R I + +P C S P
Sbjct: 142 QHRVLISIFTVSPNLRPVNE-KLEAYILDPRGS-RMIEWRHL--KPFCCGITNMSFPLSD 197
Query: 299 --VVPGWTKAIVIGRHAHGDQYKAQDFVVPK-------PGKVELVYTAEDGTTEKRLLYD 451
V+ W + + HA+ ++ Q +V+PK P ++ + E GT R Y
Sbjct: 198 QPVLGEWFIFVEMQGHAYNKSFEVQKYVLPKFELLIDPPRYIQDLDACETGTVRAR--YT 255
Query: 452 FKTPGVVLGMYNIDESIRAFAHSSFQV 532
F P V G I+ ++ + S +V
Sbjct: 256 FGKP--VAGALTINMTVNGVGYYSHEV 280
>AY101765-1|AAM50084.1| 1885|Homo sapiens C3 and PZP-like
alpha-2-macroglobulin domain containing 8 protein.
Length = 1885
Score = 29.5 bits (63), Expect = 9.5
Identities = 39/147 (26%), Positives = 64/147 (43%), Gaps = 15/147 (10%)
Frame = +2
Query: 137 KHNVGIKCATITPDEQRVEEFKLKKMWLSPNGTIRNILGGTVFREPILC----KSIPR-- 298
+H V I T++P+ + V E KL+ L P G+ R I + +P C S P
Sbjct: 142 QHRVLISIFTVSPNLRPVNE-KLEAYILDPRGS-RMIEWRHL--KPFCCGITNMSFPLSD 197
Query: 299 --VVPGWTKAIVIGRHAHGDQYKAQDFVVPK-------PGKVELVYTAEDGTTEKRLLYD 451
V+ W + + HA+ ++ Q +V+PK P ++ + E GT R Y
Sbjct: 198 QPVLGEWFIFVEMQGHAYNKSFEVQKYVLPKFELLIDPPRYIQDLDACETGTVRAR--YT 255
Query: 452 FKTPGVVLGMYNIDESIRAFAHSSFQV 532
F P V G I+ ++ + S +V
Sbjct: 256 FGKP--VAGALTINMTVNGVGYYSHEV 280
>AB033109-1|BAA86597.1| 1884|Homo sapiens KIAA1283 protein protein.
Length = 1884
Score = 29.5 bits (63), Expect = 9.5
Identities = 39/147 (26%), Positives = 64/147 (43%), Gaps = 15/147 (10%)
Frame = +2
Query: 137 KHNVGIKCATITPDEQRVEEFKLKKMWLSPNGTIRNILGGTVFREPILC----KSIPR-- 298
+H V I T++P+ + V E KL+ L P G+ R I + +P C S P
Sbjct: 141 QHRVLISIFTVSPNLRPVNE-KLEAYILDPRGS-RMIEWRHL--KPFCCGITNMSFPLSD 196
Query: 299 --VVPGWTKAIVIGRHAHGDQYKAQDFVVPK-------PGKVELVYTAEDGTTEKRLLYD 451
V+ W + + HA+ ++ Q +V+PK P ++ + E GT R Y
Sbjct: 197 QPVLGEWFIFVEMQGHAYNKSFEVQKYVLPKFELLIDPPRYIQDLDACETGTVRAR--YT 254
Query: 452 FKTPGVVLGMYNIDESIRAFAHSSFQV 532
F P V G I+ ++ + S +V
Sbjct: 255 FGKP--VAGALTINMTVNGVGYYSHEV 279
Database: human
Posted date: Oct 23, 2007 1:18 PM
Number of letters in database: 76,859,062
Number of sequences in database: 237,096
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 93,830,168
Number of Sequences: 237096
Number of extensions: 2146286
Number of successful extensions: 8330
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 8058
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 8314
length of database: 76,859,062
effective HSP length: 87
effective length of database: 56,231,710
effective search space used: 6354183230
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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