Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= I10A02NGRL0007_B04
(521 letters)
Database: human
237,096 sequences; 76,859,062 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
X69151-1|CAA48903.1| 382|Homo sapiens vacuolar proton-ATPase pr... 58 2e-08
BC010960-1|AAH10960.1| 382|Homo sapiens ATPase, H+ transporting... 58 2e-08
AF363578-1|AAL50383.1| 382|Homo sapiens ATPase H+ transporting ... 58 2e-08
BC012142-1|AAH12142.1| 381|Homo sapiens ATPase, H+ transporting... 53 5e-07
AY039759-1|AAK83464.1| 381|Homo sapiens V-ATPase C2 subunit pro... 53 5e-07
AC092687-2|AAY24069.1| 381|Homo sapiens unknown protein. 53 5e-07
J05682-1|AAA36803.1| 347|Homo sapiens H+ -ATPase C subunit prot... 48 2e-05
X87160-1|CAA60633.1| 649|Homo sapiens epithelial amiloride-sens... 31 2.4
U35630-1|AAC50217.1| 126|Homo sapiens epithelial sodium channel... 31 2.4
DQ402524-1|ABD72220.1| 649|Homo sapiens nasal epithelial sodium... 31 2.4
BC069652-1|AAH69652.1| 649|Homo sapiens sodium channel, nonvolt... 31 2.4
BC059391-1|AAH59391.1| 649|Homo sapiens sodium channel, nonvolt... 31 2.4
AF356502-1|AAK50910.1| 649|Homo sapiens amiloride-sensitive epi... 31 2.4
L36592-1|AAA75460.1| 649|Homo sapiens epithelial sodium channel... 30 4.3
>X69151-1|CAA48903.1| 382|Homo sapiens vacuolar proton-ATPase
protein.
Length = 382
Score = 57.6 bits (133), Expect = 2e-08
Identities = 34/79 (43%), Positives = 46/79 (58%), Gaps = 2/79 (2%)
Frame = +3
Query: 57 MSEYWVISAPVRPELCSRLGEPLN--NGHKSGQPPVSNY*FPNTCI*RWGNWDQLVGLSD 230
M+E+W+ISAP + C + E L+ + S + P+ + G D LVGLSD
Sbjct: 1 MTEFWLISAPGE-KTCQQTWEKLHAATSKNNNLAVTSKFNIPDLKV---GTLDVLVGLSD 56
Query: 231 DLGKLDTFVEGVTRKVAQY 287
+L KLD FVEGV +KVAQY
Sbjct: 57 ELAKLDAFVEGVVKKVAQY 75
Score = 38.7 bits (86), Expect = 0.012
Identities = 28/76 (36%), Positives = 42/76 (55%), Gaps = 4/76 (5%)
Frame = +2
Query: 299 VLEDQRDKLHENLMAE*QCTTNLLGHVSSGTWPSIH---*TDLRNI-RIL*QTVGQIDAD 466
VLED +DK+ ENL+A +L+ +++ W L+NI I+ + V QID D
Sbjct: 79 VLEDSKDKVQENLLAN---GVDLVTYITRFQWDMAKYPIKQSLKNISEIIAKGVTQIDND 135
Query: 467 LKVKSAAYKALKAIYQ 514
LK +++AY LK Q
Sbjct: 136 LKSRASAYNNLKGNLQ 151
Score = 37.9 bits (84), Expect = 0.021
Identities = 21/51 (41%), Positives = 33/51 (64%), Gaps = 2/51 (3%)
Frame = +1
Query: 373 TRFQWDLAKYPLNRSTQH-TDIIANSGTDRCR-LEG*ISSVQSSQGHLPNL 519
TRFQWD+AKYP+ +S ++ ++IIA T L+ S+ + +G+L NL
Sbjct: 103 TRFQWDMAKYPIKQSLKNISEIIAKGVTQIDNDLKSRASAYNNLKGNLQNL 153
>BC010960-1|AAH10960.1| 382|Homo sapiens ATPase, H+ transporting,
lysosomal 42kDa, V1 subunit C1 protein.
Length = 382
Score = 57.6 bits (133), Expect = 2e-08
Identities = 34/79 (43%), Positives = 46/79 (58%), Gaps = 2/79 (2%)
Frame = +3
Query: 57 MSEYWVISAPVRPELCSRLGEPLN--NGHKSGQPPVSNY*FPNTCI*RWGNWDQLVGLSD 230
M+E+W+ISAP + C + E L+ + S + P+ + G D LVGLSD
Sbjct: 1 MTEFWLISAPGE-KTCQQTWEKLHAATSKNNNLAVTSKFNIPDLKV---GTLDVLVGLSD 56
Query: 231 DLGKLDTFVEGVTRKVAQY 287
+L KLD FVEGV +KVAQY
Sbjct: 57 ELAKLDAFVEGVVKKVAQY 75
Score = 38.7 bits (86), Expect = 0.012
Identities = 28/76 (36%), Positives = 42/76 (55%), Gaps = 4/76 (5%)
Frame = +2
Query: 299 VLEDQRDKLHENLMAE*QCTTNLLGHVSSGTWPSIH---*TDLRNI-RIL*QTVGQIDAD 466
VLED +DK+ ENL+A +L+ +++ W L+NI I+ + V QID D
Sbjct: 79 VLEDSKDKVQENLLAN---GVDLVTYITRFQWDMAKYPIKQSLKNISEIIAKGVTQIDND 135
Query: 467 LKVKSAAYKALKAIYQ 514
LK +++AY LK Q
Sbjct: 136 LKSRASAYNNLKGNLQ 151
Score = 37.9 bits (84), Expect = 0.021
Identities = 21/51 (41%), Positives = 33/51 (64%), Gaps = 2/51 (3%)
Frame = +1
Query: 373 TRFQWDLAKYPLNRSTQH-TDIIANSGTDRCR-LEG*ISSVQSSQGHLPNL 519
TRFQWD+AKYP+ +S ++ ++IIA T L+ S+ + +G+L NL
Sbjct: 103 TRFQWDMAKYPIKQSLKNISEIIAKGVTQIDNDLKSRASAYNNLKGNLQNL 153
>AF363578-1|AAL50383.1| 382|Homo sapiens ATPase H+ transporting
lysosomal protein protein.
Length = 382
Score = 57.6 bits (133), Expect = 2e-08
Identities = 34/79 (43%), Positives = 46/79 (58%), Gaps = 2/79 (2%)
Frame = +3
Query: 57 MSEYWVISAPVRPELCSRLGEPLN--NGHKSGQPPVSNY*FPNTCI*RWGNWDQLVGLSD 230
M+E+W+ISAP + C + E L+ + S + P+ + G D LVGLSD
Sbjct: 1 MTEFWLISAPGE-KTCQQTWEKLHAATSKNNNLAVTSKFNIPDLKV---GTLDVLVGLSD 56
Query: 231 DLGKLDTFVEGVTRKVAQY 287
+L KLD FVEGV +KVAQY
Sbjct: 57 ELAKLDAFVEGVVKKVAQY 75
Score = 38.7 bits (86), Expect = 0.012
Identities = 28/76 (36%), Positives = 42/76 (55%), Gaps = 4/76 (5%)
Frame = +2
Query: 299 VLEDQRDKLHENLMAE*QCTTNLLGHVSSGTWPSIH---*TDLRNI-RIL*QTVGQIDAD 466
VLED +DK+ ENL+A +L+ +++ W L+NI I+ + V QID D
Sbjct: 79 VLEDSKDKVQENLLAN---GVDLVTYITRFQWDMAKYPIKQSLKNISEIIAKGVTQIDND 135
Query: 467 LKVKSAAYKALKAIYQ 514
LK +++AY LK Q
Sbjct: 136 LKSRASAYNNLKGNLQ 151
Score = 37.9 bits (84), Expect = 0.021
Identities = 21/51 (41%), Positives = 33/51 (64%), Gaps = 2/51 (3%)
Frame = +1
Query: 373 TRFQWDLAKYPLNRSTQH-TDIIANSGTDRCR-LEG*ISSVQSSQGHLPNL 519
TRFQWD+AKYP+ +S ++ ++IIA T L+ S+ + +G+L NL
Sbjct: 103 TRFQWDMAKYPIKQSLKNISEIIAKGVTQIDNDLKSRASAYNNLKGNLQNL 153
>BC012142-1|AAH12142.1| 381|Homo sapiens ATPase, H+ transporting,
lysosomal 42kDa, V1 subunit C2 protein.
Length = 381
Score = 53.2 bits (122), Expect = 5e-07
Identities = 32/76 (42%), Positives = 42/76 (55%)
Frame = +3
Query: 57 MSEYWVISAPVRPELCSRLGEPLNNGHKSGQPPVSNY*FPNTCI*RWGNWDQLVGLSDDL 236
MSE+W+ISAP E L KS + + P+ + G D LVGLSD+L
Sbjct: 1 MSEFWLISAPGDKENLQALERMNTVTSKSNLSYNTKFAIPDFKV---GTLDSLVGLSDEL 57
Query: 237 GKLDTFVEGVTRKVAQ 284
GKLDTF E + R++AQ
Sbjct: 58 GKLDTFAESLIRRMAQ 73
Score = 31.1 bits (67), Expect = 2.4
Identities = 21/72 (29%), Positives = 38/72 (52%), Gaps = 2/72 (2%)
Frame = +2
Query: 293 VRVLEDQRDKLHENLMAE*QCTTNLLGHVS--SGTWPSIH*TDLRNIRIL*QTVGQIDAD 466
V V+ED + K+ E+L+A T+ + H +P + + + + + + QI+ D
Sbjct: 76 VEVMEDSKGKVQEHLLANGVDLTSFVTHFEWDMAKYP-VKQPLVSVVDTIAKQLAQIEMD 134
Query: 467 LKVKSAAYKALK 502
LK ++AAY LK
Sbjct: 135 LKSRTAAYDTLK 146
>AY039759-1|AAK83464.1| 381|Homo sapiens V-ATPase C2 subunit
protein.
Length = 381
Score = 53.2 bits (122), Expect = 5e-07
Identities = 32/76 (42%), Positives = 42/76 (55%)
Frame = +3
Query: 57 MSEYWVISAPVRPELCSRLGEPLNNGHKSGQPPVSNY*FPNTCI*RWGNWDQLVGLSDDL 236
MSE+W+ISAP E L KS + + P+ + G D LVGLSD+L
Sbjct: 1 MSEFWLISAPGDKENLQALERMNTVTSKSNLSYNTKFAIPDFKV---GTLDSLVGLSDEL 57
Query: 237 GKLDTFVEGVTRKVAQ 284
GKLDTF E + R++AQ
Sbjct: 58 GKLDTFAESLIRRMAQ 73
Score = 31.5 bits (68), Expect = 1.9
Identities = 21/72 (29%), Positives = 38/72 (52%), Gaps = 2/72 (2%)
Frame = +2
Query: 293 VRVLEDQRDKLHENLMAE*QCTTNLLGHVS--SGTWPSIH*TDLRNIRIL*QTVGQIDAD 466
V V+ED + K+ E+L+A T+ + H +P + + + + + + QI+ D
Sbjct: 76 VEVMEDSKGKVQEHLLANGVDLTSFVTHFEWDMAKYP-VKQPLVSVVDTIAKQLAQIEMD 134
Query: 467 LKVKSAAYKALK 502
LK ++AAY LK
Sbjct: 135 LKSRTAAYNTLK 146
>AC092687-2|AAY24069.1| 381|Homo sapiens unknown protein.
Length = 381
Score = 53.2 bits (122), Expect = 5e-07
Identities = 32/76 (42%), Positives = 42/76 (55%)
Frame = +3
Query: 57 MSEYWVISAPVRPELCSRLGEPLNNGHKSGQPPVSNY*FPNTCI*RWGNWDQLVGLSDDL 236
MSE+W+ISAP E L KS + + P+ + G D LVGLSD+L
Sbjct: 1 MSEFWLISAPGDKENLQALERMNTVTSKSNLSYNTKFAIPDFKV---GTLDSLVGLSDEL 57
Query: 237 GKLDTFVEGVTRKVAQ 284
GKLDTF E + R++AQ
Sbjct: 58 GKLDTFAESLIRRMAQ 73
Score = 31.5 bits (68), Expect = 1.9
Identities = 21/72 (29%), Positives = 38/72 (52%), Gaps = 2/72 (2%)
Frame = +2
Query: 293 VRVLEDQRDKLHENLMAE*QCTTNLLGHVS--SGTWPSIH*TDLRNIRIL*QTVGQIDAD 466
V V+ED + K+ E+L+A T+ + H +P + + + + + + QI+ D
Sbjct: 76 VEVMEDSKGKVQEHLLANGVDLTSFVTHFEWDMAKYP-VKQPLVSVVDTIAKQLAQIEMD 134
Query: 467 LKVKSAAYKALK 502
LK ++AAY LK
Sbjct: 135 LKSRTAAYNTLK 146
>J05682-1|AAA36803.1| 347|Homo sapiens H+ -ATPase C subunit
protein.
Length = 347
Score = 48.0 bits (109), Expect = 2e-05
Identities = 22/30 (73%), Positives = 24/30 (80%)
Frame = +3
Query: 198 GNWDQLVGLSDDLGKLDTFVEGVTRKVAQY 287
G D LVGLSD+L KLD FVEGV +KVAQY
Sbjct: 11 GTLDVLVGLSDELAKLDAFVEGVVKKVAQY 40
Score = 38.7 bits (86), Expect = 0.012
Identities = 28/76 (36%), Positives = 42/76 (55%), Gaps = 4/76 (5%)
Frame = +2
Query: 299 VLEDQRDKLHENLMAE*QCTTNLLGHVSSGTWPSIH---*TDLRNI-RIL*QTVGQIDAD 466
VLED +DK+ ENL+A +L+ +++ W L+NI I+ + V QID D
Sbjct: 44 VLEDSKDKVQENLLAN---GVDLVTYITRFQWDMAKYPIKQSLKNISEIIAKGVTQIDND 100
Query: 467 LKVKSAAYKALKAIYQ 514
LK +++AY LK Q
Sbjct: 101 LKSRASAYNNLKGNLQ 116
Score = 37.9 bits (84), Expect = 0.021
Identities = 21/51 (41%), Positives = 33/51 (64%), Gaps = 2/51 (3%)
Frame = +1
Query: 373 TRFQWDLAKYPLNRSTQH-TDIIANSGTDRCR-LEG*ISSVQSSQGHLPNL 519
TRFQWD+AKYP+ +S ++ ++IIA T L+ S+ + +G+L NL
Sbjct: 68 TRFQWDMAKYPIKQSLKNISEIIAKGVTQIDNDLKSRASAYNNLKGNLQNL 118
>X87160-1|CAA60633.1| 649|Homo sapiens epithelial
amiloride-sensitive sodium channel, gamma-subunit
protein.
Length = 649
Score = 31.1 bits (67), Expect = 2.4
Identities = 25/87 (28%), Positives = 38/87 (43%)
Frame = -1
Query: 452 VPLFAIISVCCVDLFNGYLARSHWKRVQVSW*YTVIPPLNFRAVYHVGLLIPSPEILSDF 273
V + II V +D F+ +AR W++ + W + PP G P+ +I D
Sbjct: 544 VCVIEIIEVFFIDFFS-IIARRQWQKAKEWWAWKQAPPCPEAPRSPQGQDNPALDIDDDL 602
Query: 272 PSDTFNKGVQLAKVIRQPHQLIPVPPP 192
P TFN + L + Q+ PPP
Sbjct: 603 P--TFNSALHLPPALGT--QVPGTPPP 625
>U35630-1|AAC50217.1| 126|Homo sapiens epithelial sodium channel
gamma subunit protein.
Length = 126
Score = 31.1 bits (67), Expect = 2.4
Identities = 25/87 (28%), Positives = 38/87 (43%)
Frame = -1
Query: 452 VPLFAIISVCCVDLFNGYLARSHWKRVQVSW*YTVIPPLNFRAVYHVGLLIPSPEILSDF 273
V + II V +D F+ +AR W++ + W + PP G P+ +I D
Sbjct: 21 VCVIEIIEVFFIDFFS-IIARRQWQKAKEWWAWKQAPPCPEAPRSPQGQDNPALDIDDDL 79
Query: 272 PSDTFNKGVQLAKVIRQPHQLIPVPPP 192
P TFN + L + Q+ PPP
Sbjct: 80 P--TFNSALHLPPALGT--QVPGTPPP 102
>DQ402524-1|ABD72220.1| 649|Homo sapiens nasal epithelial sodium
channel gamma subunit protein.
Length = 649
Score = 31.1 bits (67), Expect = 2.4
Identities = 25/87 (28%), Positives = 38/87 (43%)
Frame = -1
Query: 452 VPLFAIISVCCVDLFNGYLARSHWKRVQVSW*YTVIPPLNFRAVYHVGLLIPSPEILSDF 273
V + II V +D F+ +AR W++ + W + PP G P+ +I D
Sbjct: 544 VCVIEIIEVFFIDFFS-IIARRQWQKAKEWWAWKQAPPCPEAPRSPQGQDNPALDIDDDL 602
Query: 272 PSDTFNKGVQLAKVIRQPHQLIPVPPP 192
P TFN + L + Q+ PPP
Sbjct: 603 P--TFNSALHLPPALGT--QVPGTPPP 625
>BC069652-1|AAH69652.1| 649|Homo sapiens sodium channel,
nonvoltage-gated 1, gamma protein.
Length = 649
Score = 31.1 bits (67), Expect = 2.4
Identities = 25/87 (28%), Positives = 38/87 (43%)
Frame = -1
Query: 452 VPLFAIISVCCVDLFNGYLARSHWKRVQVSW*YTVIPPLNFRAVYHVGLLIPSPEILSDF 273
V + II V +D F+ +AR W++ + W + PP G P+ +I D
Sbjct: 544 VCVIEIIEVFFIDFFS-IIARRQWQKAKEWWAWKQAPPCPEAPRSPQGQDNPALDIDDDL 602
Query: 272 PSDTFNKGVQLAKVIRQPHQLIPVPPP 192
P TFN + L + Q+ PPP
Sbjct: 603 P--TFNSALHLPPALGT--QVPGTPPP 625
>BC059391-1|AAH59391.1| 649|Homo sapiens sodium channel,
nonvoltage-gated 1, gamma protein.
Length = 649
Score = 31.1 bits (67), Expect = 2.4
Identities = 25/87 (28%), Positives = 38/87 (43%)
Frame = -1
Query: 452 VPLFAIISVCCVDLFNGYLARSHWKRVQVSW*YTVIPPLNFRAVYHVGLLIPSPEILSDF 273
V + II V +D F+ +AR W++ + W + PP G P+ +I D
Sbjct: 544 VCVIEIIEVFFIDFFS-IIARRQWQKAKEWWAWKQAPPCPEAPRSPQGQDNPALDIDDDL 602
Query: 272 PSDTFNKGVQLAKVIRQPHQLIPVPPP 192
P TFN + L + Q+ PPP
Sbjct: 603 P--TFNSALHLPPALGT--QVPGTPPP 625
>AF356502-1|AAK50910.1| 649|Homo sapiens amiloride-sensitive
epithelial sodium channel gamma subunit protein.
Length = 649
Score = 31.1 bits (67), Expect = 2.4
Identities = 25/87 (28%), Positives = 38/87 (43%)
Frame = -1
Query: 452 VPLFAIISVCCVDLFNGYLARSHWKRVQVSW*YTVIPPLNFRAVYHVGLLIPSPEILSDF 273
V + II V +D F+ +AR W++ + W + PP G P+ +I D
Sbjct: 544 VCVIEIIEVFFIDFFS-IIARRQWQKAKEWWAWKQAPPCPEAPRSPQGQDNPALDIDDDL 602
Query: 272 PSDTFNKGVQLAKVIRQPHQLIPVPPP 192
P TFN + L + Q+ PPP
Sbjct: 603 P--TFNSALHLPPALGT--QVPGTPPP 625
>L36592-1|AAA75460.1| 649|Homo sapiens epithelial sodium channel
gamma subunit protein.
Length = 649
Score = 30.3 bits (65), Expect = 4.3
Identities = 25/87 (28%), Positives = 38/87 (43%)
Frame = -1
Query: 452 VPLFAIISVCCVDLFNGYLARSHWKRVQVSW*YTVIPPLNFRAVYHVGLLIPSPEILSDF 273
V + II V +D F+ +AR W++ + W + PP G P+ +I D
Sbjct: 544 VCVIEIIEVFFIDFFS-IIARRQWQKAKEWWAWKQAPPCPEAPRSPQGQDNPALDIDDDL 602
Query: 272 PSDTFNKGVQLAKVIRQPHQLIPVPPP 192
P TFN + L + Q+ PPP
Sbjct: 603 P--TFNSALHLPPSLGT--QVPGTPPP 625
Database: human
Posted date: Oct 23, 2007 1:18 PM
Number of letters in database: 76,859,062
Number of sequences in database: 237,096
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 88,938,153
Number of Sequences: 237096
Number of extensions: 2161680
Number of successful extensions: 4662
Number of sequences better than 10.0: 14
Number of HSP's better than 10.0 without gapping: 4479
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 4652
length of database: 76,859,062
effective HSP length: 85
effective length of database: 56,705,902
effective search space used: 4990119376
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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