Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= I10A02NGRL0006_M15
(569 letters)
Database: uniref50
1,657,284 sequences; 575,637,011 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
UniRef50_UPI00015B4A18 Cluster: PREDICTED: similar to FPGS prote... 137 2e-31
UniRef50_UPI0000DB6E21 Cluster: PREDICTED: similar to folylpolyg... 135 6e-31
UniRef50_UPI0000E4A2B9 Cluster: PREDICTED: similar to Folylpolyg... 133 2e-30
UniRef50_Q5JU23 Cluster: Folylpolyglutamate synthase; n=2; Homo ... 129 5e-29
UniRef50_Q05932 Cluster: Folylpolyglutamate synthase, mitochondr... 129 5e-29
UniRef50_Q5TSB4 Cluster: ENSANGP00000026850; n=1; Anopheles gamb... 127 2e-28
UniRef50_UPI0000D556C6 Cluster: PREDICTED: similar to Folylpolyg... 126 4e-28
UniRef50_Q9VYL1 Cluster: CG2543-PA; n=4; Sophophora|Rep: CG2543-... 126 5e-28
UniRef50_Q09509 Cluster: Putative folylpolyglutamate synthase; n... 120 2e-26
UniRef50_Q4THS1 Cluster: Chromosome undetermined SCAF2726, whole... 111 1e-23
UniRef50_Q5KJZ3 Cluster: Tetrahydrofolylpolyglutamate synthase, ... 109 3e-23
UniRef50_O13492 Cluster: Folylpolyglutamate synthase; n=5; Peziz... 109 6e-23
UniRef50_Q54CY5 Cluster: Tetrahydrofolylpolyglutamate synthase; ... 107 2e-22
UniRef50_Q9Y893 Cluster: Folylpolyglutamate synthase; n=7; Sacch... 102 5e-21
UniRef50_Q8W038 Cluster: Folylpolyglutamate synthetase, mitochon... 101 2e-20
UniRef50_Q08645 Cluster: Folylpolyglutamate synthase; n=7; Sacch... 100 3e-20
UniRef50_Q4P7Z1 Cluster: Putative uncharacterized protein; n=1; ... 97 2e-19
UniRef50_Q2UUH9 Cluster: Folylpolyglutamate synthase; n=2; Eurot... 97 3e-19
UniRef50_Q8W040 Cluster: Folylpolyglutamate synthetase, chloropl... 96 4e-19
UniRef50_UPI0000E484D2 Cluster: PREDICTED: similar to Folylpolyg... 89 7e-17
UniRef50_Q96G81 Cluster: Folylpolyglutamate synthase; n=2; Euthe... 89 7e-17
UniRef50_A7PIN0 Cluster: Chromosome chr13 scaffold_17, whole gen... 88 1e-16
UniRef50_A4S2I3 Cluster: Predicted protein; n=2; Ostreococcus|Re... 87 4e-16
UniRef50_Q9M059 Cluster: Tetrahydrofolylpolyglutamate synthase-l... 86 6e-16
UniRef50_Q2UGP7 Cluster: Folylpolyglutamate synthase; n=10; Pezi... 86 6e-16
UniRef50_O74742 Cluster: Probable folylpolyglutamate synthase; n... 86 6e-16
UniRef50_Q9VQW0 Cluster: CG31773-PA; n=1; Drosophila melanogaste... 85 1e-15
UniRef50_A4RLF6 Cluster: Putative uncharacterized protein; n=1; ... 83 3e-15
UniRef50_UPI0000587E85 Cluster: PREDICTED: similar to Folylpolyg... 82 1e-14
UniRef50_A6R4T6 Cluster: Putative uncharacterized protein; n=2; ... 81 2e-14
UniRef50_Q4Q1G0 Cluster: Folylpolyglutamate synthetase; n=6; Try... 79 5e-14
UniRef50_Q16KT7 Cluster: Folylpolyglutamate synthase; n=1; Aedes... 79 7e-14
UniRef50_A2G107 Cluster: FolC bifunctional protein; n=1; Trichom... 75 9e-13
UniRef50_A6PUD4 Cluster: FolC bifunctional protein; n=1; Victiva... 74 3e-12
UniRef50_A2QCB5 Cluster: Contig An02c0080, complete genome; n=6;... 73 4e-12
UniRef50_A5KLT5 Cluster: Putative uncharacterized protein; n=1; ... 73 5e-12
UniRef50_A3ESF6 Cluster: Folylpolyglutamate synthase; n=1; Lepto... 73 6e-12
UniRef50_A7EG57 Cluster: Putative uncharacterized protein; n=1; ... 73 6e-12
UniRef50_A6SID8 Cluster: Putative uncharacterized protein; n=1; ... 73 6e-12
UniRef50_Q01UR3 Cluster: FolC bifunctional protein; n=1; Solibac... 72 8e-12
UniRef50_A6BCX0 Cluster: Putative uncharacterized protein; n=2; ... 72 8e-12
UniRef50_Q6DKZ3 Cluster: Dihydrofolate/folylpolyglutamate syntha... 70 3e-11
UniRef50_A6C8Q2 Cluster: Folyl-polyglutamate synthetase; n=1; Pl... 70 4e-11
UniRef50_Q8G4M5 Cluster: Folylpolyglutamate synthase; n=4; Bifid... 69 6e-11
UniRef50_A5FP87 Cluster: FolC bifunctional protein; n=3; Dehaloc... 69 6e-11
UniRef50_A5D456 Cluster: Folylpolyglutamate synthase; n=1; Pelot... 69 6e-11
UniRef50_A0LIV6 Cluster: FolC bifunctional protein; n=1; Syntrop... 69 6e-11
UniRef50_Q1PZI3 Cluster: Similar to multifunctional folylpolyglu... 69 1e-10
UniRef50_Q1EVW0 Cluster: Folylpolyglutamate synthetase; n=1; Clo... 69 1e-10
UniRef50_A4VSD9 Cluster: Folylpolyglutamate synthase; n=2; Strep... 69 1e-10
UniRef50_UPI000023EDF3 Cluster: hypothetical protein FG00685.1; ... 68 1e-10
UniRef50_Q6A9I9 Cluster: Folylpolyglutamate synthase; n=1; Propi... 68 1e-10
UniRef50_Q9FN53 Cluster: Folylpolyglutamate synthase-like protei... 68 1e-10
UniRef50_Q8W041 Cluster: Dihydrofolate synthetase; n=5; core eud... 68 1e-10
UniRef50_O67833 Cluster: Folylpolyglutamate synthetase; n=1; Aqu... 68 2e-10
UniRef50_Q03Y79 Cluster: Folylpolyglutamate synthase; n=1; Leuco... 68 2e-10
UniRef50_A6LA17 Cluster: Folylpolyglutamate synthase; n=2; Parab... 68 2e-10
UniRef50_Q7SFD9 Cluster: Putative uncharacterized protein NCU008... 68 2e-10
UniRef50_A2QK88 Cluster: Contig An04c0360, complete genome; n=2;... 68 2e-10
UniRef50_A1K4B2 Cluster: Dihydrofolate synthase / Tetrahydrofoly... 67 2e-10
UniRef50_Q62AJ8 Cluster: FolC bifunctional protein; n=25; Betapr... 67 3e-10
UniRef50_Q31PP5 Cluster: FolC bifunctional protein; n=2; Synecho... 67 3e-10
UniRef50_A7CTY2 Cluster: FolC bifunctional protein; n=1; Opituta... 67 3e-10
UniRef50_A5ZW55 Cluster: Putative uncharacterized protein; n=1; ... 67 3e-10
UniRef50_A5VL10 Cluster: FolC bifunctional protein; n=2; Lactoba... 67 3e-10
UniRef50_Q38WN1 Cluster: Folylpolyglutamate synthase; n=1; Lacto... 66 4e-10
UniRef50_A5WDG9 Cluster: FolC bifunctional protein; n=3; Psychro... 66 4e-10
UniRef50_A5KJF0 Cluster: Putative uncharacterized protein; n=2; ... 66 4e-10
UniRef50_A5CR24 Cluster: FolC protein; n=4; Actinobacteria (clas... 66 4e-10
UniRef50_Q38AL2 Cluster: Folylpolyglutamate-dihydrofolate synthe... 66 4e-10
UniRef50_Q04E69 Cluster: Folylpolyglutamate synthase; n=2; Oenoc... 66 5e-10
UniRef50_Q7UQM1 Cluster: Folylpolyglutamate synthase/dihydrofola... 66 7e-10
UniRef50_Q3A6L0 Cluster: Folylpolyglutamate synthetase; dihydrof... 66 7e-10
UniRef50_Q12D50 Cluster: FolC bifunctional protein; n=1; Polarom... 66 7e-10
UniRef50_A5ZI35 Cluster: Putative uncharacterized protein; n=1; ... 66 7e-10
UniRef50_A5FMS8 Cluster: FolC bifunctional protein; n=14; Bacter... 66 7e-10
UniRef50_Q727H3 Cluster: Folylpolyglutamate synthase; n=2; Desul... 65 1e-09
UniRef50_Q0LMK1 Cluster: FolC bifunctional protein; n=1; Herpeto... 65 1e-09
UniRef50_A7LS10 Cluster: Putative uncharacterized protein; n=1; ... 65 1e-09
UniRef50_A1SMD5 Cluster: FolC bifunctional protein; n=5; Actinom... 65 1e-09
UniRef50_A0UYZ7 Cluster: FolC bifunctional protein; n=1; Clostri... 65 1e-09
UniRef50_Q1FIY8 Cluster: FolC bifunctional protein; n=1; Clostri... 65 1e-09
UniRef50_A3IEY2 Cluster: Folyl-polyglutamate synthetase; n=1; Ba... 65 1e-09
UniRef50_Q3JCB5 Cluster: Folylpolyglutamate synthetase; n=1; Nit... 64 2e-09
UniRef50_A4RLF9 Cluster: Putative uncharacterized protein; n=1; ... 64 2e-09
UniRef50_Q7MWW9 Cluster: Folylpolyglutamate synthase; n=2; Bacte... 64 2e-09
UniRef50_Q4P0W7 Cluster: Putative uncharacterized protein; n=1; ... 64 2e-09
UniRef50_A7D4G5 Cluster: Dihydropteroate synthase; n=1; Halorubr... 64 2e-09
UniRef50_Q2LQC5 Cluster: Folylpolyglutamate synthase / dihydrofo... 64 3e-09
UniRef50_A6TN35 Cluster: FolC bifunctional protein; n=2; Clostri... 64 3e-09
UniRef50_A4M5Q3 Cluster: FolC bifunctional protein; n=1; Petroto... 64 3e-09
UniRef50_A3ZWP1 Cluster: Folyl-polyglutamate synthetase; n=1; Bl... 64 3e-09
UniRef50_Q6MAP9 Cluster: Putative folylpolyglutamate synthase; n... 63 4e-09
UniRef50_Q8RBN3 Cluster: Folylpolyglutamate synthase; n=5; Clost... 63 5e-09
UniRef50_Q8A839 Cluster: Folylpolyglutamate synthase; n=1; Bacte... 63 5e-09
UniRef50_A6WDS1 Cluster: FolC bifunctional protein precursor; n=... 63 5e-09
UniRef50_Q1IVH6 Cluster: FolC bifunctional protein; n=1; Acidoba... 62 7e-09
UniRef50_Q1D8V1 Cluster: Tetrahydrofolylpolyglutamate synthase/d... 62 7e-09
UniRef50_A3HTE9 Cluster: Folylpolyglutamate synthase; n=3; Bacte... 62 7e-09
UniRef50_A0YB05 Cluster: FolC bifunctional protein; n=1; marine ... 62 7e-09
UniRef50_Q13EI5 Cluster: FolC bifunctional protein; n=3; Rhodops... 62 9e-09
UniRef50_Q1QY39 Cluster: FolC bifunctional protein; n=1; Chromoh... 62 9e-09
UniRef50_A1W9F5 Cluster: FolC bifunctional protein; n=33; Burkho... 62 9e-09
UniRef50_Q8XJ43 Cluster: Folyl-polyglutamate synthetase; n=13; C... 62 1e-08
UniRef50_Q2RNS0 Cluster: Folylpolyglutamate synthetase; n=4; Rho... 62 1e-08
UniRef50_O83360 Cluster: Folylpolyglutamate synthetase; n=1; Tre... 62 1e-08
UniRef50_Q1MS38 Cluster: Folylpolyglutamate synthase; n=1; Lawso... 62 1e-08
UniRef50_A5TUM3 Cluster: Tetrahydrofolate synthase; n=3; Fusobac... 62 1e-08
UniRef50_Q2QLY6 Cluster: Dihydrofolate synthetase/folylpolygluta... 62 1e-08
UniRef50_Q0ILT5 Cluster: Os12g0623800 protein; n=2; Oryza sativa... 62 1e-08
UniRef50_Q64S09 Cluster: Folylpolyglutamate synthase; n=2; Bacte... 61 2e-08
UniRef50_Q5SLF0 Cluster: Folyl-polyglutamate synthetase; n=4; De... 61 2e-08
UniRef50_Q31HH1 Cluster: FolC bifunctional folylpolyglutamate sy... 61 2e-08
UniRef50_Q1N6P7 Cluster: Folylpolyglutamate synthetase; n=1; Oce... 61 2e-08
UniRef50_Q18QE7 Cluster: FolC bifunctional protein; n=5; Clostri... 61 2e-08
UniRef50_Q88ST5 Cluster: Folylpolyglutamate synthase; n=1; Lacto... 61 2e-08
UniRef50_Q0AWF7 Cluster: Putative uncharacterized protein; n=1; ... 61 2e-08
UniRef50_A6D0N3 Cluster: Folylpolyglutamate synthase; n=1; Vibri... 61 2e-08
UniRef50_A3VQ98 Cluster: FolC bifunctional protein; n=1; Parvula... 61 2e-08
UniRef50_A3TFM8 Cluster: Putative folylpolyglutamate synthase; n... 61 2e-08
UniRef50_Q73NR8 Cluster: Folylpolyglutamate synthetase, putative... 60 3e-08
UniRef50_Q6FEE4 Cluster: Bifunctional protein [Includes: folylpo... 60 3e-08
UniRef50_Q2JDQ6 Cluster: FolC bifunctional protein; n=2; Frankia... 60 3e-08
UniRef50_Q3DZP5 Cluster: Folylpolyglutamate synthetase; n=2; Chl... 60 3e-08
UniRef50_Q12P54 Cluster: FolC bifunctional protein; n=6; Shewane... 60 3e-08
UniRef50_A4RKT0 Cluster: Putative uncharacterized protein; n=1; ... 60 3e-08
UniRef50_Q30WU4 Cluster: FolC bifunctional protein; n=1; Desulfo... 60 4e-08
UniRef50_Q5CBK3 Cluster: Folylpolyglutamate synthase/dihydrofola... 60 4e-08
UniRef50_A1HP48 Cluster: FolC bifunctional protein; n=1; Thermos... 60 4e-08
UniRef50_Q6B7M6 Cluster: FolC-P protein; n=1; Haloferax volcanii... 60 4e-08
UniRef50_Q2RZW2 Cluster: Dihydrofolate synthetase; n=1; Saliniba... 60 5e-08
UniRef50_Q0A999 Cluster: FolC bifunctional protein; n=1; Alkalil... 60 5e-08
UniRef50_A6FEP3 Cluster: Dihydrofolate synthase / folylpolygluta... 60 5e-08
UniRef50_A6DMK1 Cluster: Folylpolyglutamate synthase; n=1; Lenti... 60 5e-08
UniRef50_A3JGB7 Cluster: Folylpolyglutamate synthetase; n=3; Mar... 60 5e-08
UniRef50_A5K2Z0 Cluster: Dihydrofolate synthase/folylpolyglutama... 60 5e-08
UniRef50_Q758R3 Cluster: AEL310Cp; n=1; Eremothecium gossypii|Re... 60 5e-08
UniRef50_Q8KFQ9 Cluster: Folylpolyglutamate synthase; n=1; Chlor... 59 6e-08
UniRef50_Q5C3N8 Cluster: SJCHGC04288 protein; n=1; Schistosoma j... 59 6e-08
UniRef50_Q9PC39 Cluster: Folylpolyglutamate synthase/dihydrofola... 59 8e-08
UniRef50_Q6AJ73 Cluster: Related to folylpolyglutamate synthase;... 59 8e-08
UniRef50_Q604P6 Cluster: Folylpolyglutamate synthase/dihydrofola... 59 8e-08
UniRef50_Q1WT76 Cluster: Folylpolyglutamate synthase / Dihydrofo... 59 8e-08
UniRef50_A4A847 Cluster: Folylpolyglutamate synthase/dihydrofola... 59 8e-08
UniRef50_Q7NLP7 Cluster: Folylpolyglutamate synthase; n=1; Gloeo... 58 1e-07
UniRef50_Q74AI6 Cluster: FolC bifunctional protein; n=5; Geobact... 58 1e-07
UniRef50_Q2JLQ4 Cluster: Folylpolyglutamate synthase; n=2; Synec... 58 1e-07
UniRef50_Q6M382 Cluster: FOLYLPOLYGLUTAMATE SYNTHASE; n=32; Acti... 58 1e-07
UniRef50_A5ZWM5 Cluster: Putative uncharacterized protein; n=1; ... 58 1e-07
UniRef50_A4BRV9 Cluster: Folylpolyglutamate synthase/dihydrofola... 58 1e-07
UniRef50_Q0BWJ9 Cluster: Putative folylpolyglutamate synthase; n... 58 1e-07
UniRef50_P43775 Cluster: Folylpolyglutamate synthase; n=101; Gam... 58 1e-07
UniRef50_Q9HZA8 Cluster: Folylpolyglutamate synthetase; n=18; Ps... 58 2e-07
UniRef50_Q2BMN3 Cluster: Folylpolyglutamate synthase; n=1; Neptu... 58 2e-07
UniRef50_A0W7P3 Cluster: FolC bifunctional protein precursor; n=... 58 2e-07
UniRef50_Q5KCY2 Cluster: Dihydrofolate synthase, putative; n=1; ... 58 2e-07
UniRef50_UPI00005100A3 Cluster: COG0285: Folylpolyglutamate synt... 57 3e-07
UniRef50_Q5QWH7 Cluster: Folylpolyglutamate synthase; n=2; Idiom... 57 3e-07
UniRef50_Q03Z01 Cluster: Folylpolyglutamate synthase; n=1; Leuco... 57 3e-07
UniRef50_A1ZCQ8 Cluster: Folylpolyglutamate synthase; n=1; Micro... 57 3e-07
UniRef50_A6SPC7 Cluster: Putative uncharacterized protein; n=2; ... 57 3e-07
UniRef50_Q7VAS8 Cluster: Folylpolyglutamate synthase; n=3; Proch... 57 3e-07
UniRef50_Q3B220 Cluster: Folylpolyglutamate synthetase; n=7; Chl... 57 3e-07
UniRef50_Q40KD4 Cluster: Folylpolyglutamate synthetase; n=12; Ri... 57 3e-07
UniRef50_Q0P9G6 Cluster: Folylpolyglutamate synthase/dihydrofola... 57 3e-07
UniRef50_A6Q510 Cluster: Folylpolyglutamate synthase; n=1; Nitra... 57 3e-07
UniRef50_A5Z386 Cluster: Putative uncharacterized protein; n=1; ... 57 3e-07
UniRef50_Q97SN7 Cluster: Dihydrofolate synthetase; n=15; Strepto... 56 4e-07
UniRef50_Q8EPN5 Cluster: Folyl-polyglutamate synthase; n=1; Ocea... 56 4e-07
UniRef50_Q7VRV1 Cluster: Folylpolyglutamate synthase; n=2; Candi... 56 4e-07
UniRef50_Q1JHI7 Cluster: Folylpolyglutamate synthase / Dihydrofo... 56 4e-07
UniRef50_A5V1W9 Cluster: FolC bifunctional protein; n=2; Roseifl... 56 4e-07
UniRef50_A3IEY3 Cluster: FolC; n=1; Bacillus sp. B14905|Rep: Fol... 56 4e-07
UniRef50_Q9U738 Cluster: Dihydrofolate synthase/folylpolyglutama... 56 4e-07
UniRef50_A0ECV5 Cluster: Chromosome undetermined scaffold_9, who... 56 4e-07
UniRef50_Q05865 Cluster: Folylpolyglutamate synthase; n=4; Bacil... 56 4e-07
UniRef50_Q2ZYL0 Cluster: Folylpolyglutamate synthetase; n=5; Str... 56 6e-07
UniRef50_Q0AGX2 Cluster: FolC bifunctional protein; n=1; Nitroso... 56 6e-07
UniRef50_A7HDB5 Cluster: FolC bifunctional protein; n=2; Anaerom... 56 6e-07
UniRef50_A7DJF5 Cluster: FolC bifunctional protein; n=1; Methylo... 56 6e-07
UniRef50_P73842 Cluster: Folyl-polyglutamate synthetase; n=10; C... 56 8e-07
UniRef50_Q5VAN8 Cluster: FolC; n=63; Alphaproteobacteria|Rep: Fo... 56 8e-07
UniRef50_A6DD55 Cluster: Folylpolyglutamate synthetase; n=1; Cam... 56 8e-07
UniRef50_Q68WJ9 Cluster: Folylpolyglutamate synthase; n=11; Rick... 55 1e-06
UniRef50_Q5FKW4 Cluster: Folylpolyglutamate synthase; n=6; Lacto... 55 1e-06
UniRef50_Q1JY09 Cluster: FolC bifunctional protein; n=1; Desulfu... 55 1e-06
UniRef50_Q1GU94 Cluster: FolC bifunctional protein; n=5; Sphingo... 55 1e-06
UniRef50_Q1AVT2 Cluster: FolC bifunctional protein; n=1; Rubroba... 55 1e-06
UniRef50_A4XL37 Cluster: FolC bifunctional protein; n=2; Clostri... 55 1e-06
UniRef50_A4E6Z7 Cluster: Putative uncharacterized protein; n=1; ... 55 1e-06
UniRef50_A4BHC7 Cluster: FolC bifunctional folylpolyglutamate sy... 55 1e-06
UniRef50_A1SW71 Cluster: FolC bifunctional protein; n=2; Psychro... 55 1e-06
UniRef50_Q9K8G9 Cluster: Folyl-polyglutamate synthetase; n=1; Ba... 54 2e-06
UniRef50_Q8D2P3 Cluster: FolC protein; n=1; Wigglesworthia gloss... 54 2e-06
UniRef50_Q88UX8 Cluster: Folylpolyglutamate synthase; n=2; Lacto... 54 2e-06
UniRef50_Q4AKU0 Cluster: Folylpolyglutamate synthetase; n=1; Chl... 54 2e-06
UniRef50_Q0ATK3 Cluster: FolC bifunctional protein; n=1; Maricau... 54 2e-06
UniRef50_Q0AQK7 Cluster: FolC bifunctional protein; n=1; Maricau... 54 2e-06
UniRef50_Q04MP6 Cluster: Folylpolyglutamate synthase; n=14; Stre... 54 2e-06
UniRef50_A5IBI5 Cluster: FolC bifunctional protein; n=4; Legione... 54 2e-06
UniRef50_Q00X21 Cluster: Dihydrofolate synthetase /folylpolyglut... 54 2e-06
UniRef50_Q9RXH3 Cluster: Folyl-polyglutamate synthetase; n=2; De... 54 2e-06
UniRef50_Q92BG3 Cluster: FolC protein; n=11; Listeria|Rep: FolC ... 54 2e-06
UniRef50_Q82ZW9 Cluster: FolC family protein; n=7; Firmicutes|Re... 54 2e-06
UniRef50_Q21IZ3 Cluster: FolC bifunctional protein; n=1; Sacchar... 54 2e-06
UniRef50_Q6CHD4 Cluster: Similar to sp|Q12676 Saccharomyces cere... 54 2e-06
UniRef50_Q8K9X3 Cluster: Bifunctional protein folC [Includes: Fo... 54 2e-06
UniRef50_UPI00015BCA34 Cluster: UPI00015BCA34 related cluster; n... 54 3e-06
UniRef50_Q9CN13 Cluster: FolC; n=7; Pasteurellaceae|Rep: FolC - ... 54 3e-06
UniRef50_Q15VG0 Cluster: FolC bifunctional protein; n=1; Pseudoa... 54 3e-06
UniRef50_Q0GL77 Cluster: Folylpolyglutamate synthase; n=3; Lacto... 54 3e-06
UniRef50_A3S1I7 Cluster: Folylpolyglutamate synthase; n=1; Proch... 54 3e-06
UniRef50_Q6KZL1 Cluster: Folylpolyglutamate synthase/dihydrofola... 54 3e-06
UniRef50_Q83D50 Cluster: FolC bifunctional protein; n=4; Coxiell... 53 4e-06
UniRef50_Q2G8T0 Cluster: FolC bifunctional protein; n=3; Sphingo... 53 4e-06
UniRef50_Q11UV3 Cluster: Tetrahydrofolylpolyglutamate synthase; ... 53 4e-06
UniRef50_Q0EXD2 Cluster: Folylpolyglutamate synthetase; n=1; Mar... 53 4e-06
UniRef50_A5EVX7 Cluster: Folylpolyglutamate synthase; n=1; Diche... 53 4e-06
UniRef50_Q83G53 Cluster: Folylpolyglutamate synthase; n=2; Troph... 53 5e-06
UniRef50_A0LA36 Cluster: FolC bifunctional protein; n=2; cellula... 53 5e-06
UniRef50_A6R127 Cluster: Putative uncharacterized protein; n=1; ... 53 5e-06
UniRef50_UPI0000DAE3B7 Cluster: hypothetical protein Rgryl_01000... 52 7e-06
UniRef50_Q7TU62 Cluster: Putuative bifunctional Dihydrofolate/Fo... 52 7e-06
UniRef50_Q5WEQ5 Cluster: Folylpolyglutamate synthase; n=1; Bacil... 52 7e-06
UniRef50_O26070 Cluster: Folylpolyglutamate synthase; n=4; Helic... 52 7e-06
UniRef50_Q41DX5 Cluster: Folylpolyglutamate synthetase; n=1; Exi... 52 7e-06
UniRef50_Q12676 Cluster: Folylpolyglutamate synthase; n=5; Sacch... 52 7e-06
UniRef50_A7C245 Cluster: Folylpolyglutamate synthase/dihydrofola... 52 1e-05
UniRef50_A1AXP8 Cluster: FolC bifunctional protein; n=3; Bacteri... 52 1e-05
UniRef50_Q9HS44 Cluster: Dihydropteroate synthase; n=4; Halobact... 52 1e-05
UniRef50_Q8UJA7 Cluster: Folylpolyglutamate synthase; n=2; Agrob... 52 1e-05
UniRef50_Q5KWL4 Cluster: Folyl-polyglutamate synthetase; n=16; B... 52 1e-05
UniRef50_Q2SJC8 Cluster: Folylpolyglutamate synthase; n=1; Hahel... 52 1e-05
UniRef50_Q1YT82 Cluster: Folylpolyglutamate synthetase; n=2; Pro... 52 1e-05
UniRef50_Q1GBX7 Cluster: Folylpolyglutamate synthase; n=2; Lacto... 52 1e-05
UniRef50_Q89AT2 Cluster: Bifunctional protein folC [Includes: Fo... 52 1e-05
UniRef50_Q2GD55 Cluster: Folylpolyglutamate synthase; n=1; Neori... 51 2e-05
UniRef50_A4B0Z4 Cluster: Bifunctional folylpolyglutamate synthas... 51 2e-05
UniRef50_Q0USC9 Cluster: Putative uncharacterized protein; n=1; ... 51 2e-05
UniRef50_UPI0000E0E8A2 Cluster: FolC bifunctional protein; n=1; ... 51 2e-05
UniRef50_Q9X7F5 Cluster: FolC protein; n=1; Methylobacterium chl... 51 2e-05
UniRef50_A7I0L8 Cluster: Folylpolyglutamate synthase; n=4; Campy... 51 2e-05
UniRef50_A6G512 Cluster: FolC bifunctional protein; n=1; Plesioc... 51 2e-05
UniRef50_A4CD05 Cluster: Bifunctional: folylpolyglutamate syntha... 51 2e-05
UniRef50_Q11KL3 Cluster: FolC bifunctional protein; n=4; Rhizobi... 50 3e-05
UniRef50_A6VWY8 Cluster: FolC bifunctional protein; n=2; Marinom... 50 3e-05
UniRef50_A6QBX4 Cluster: Folylpolyglutamate synthase; n=1; Sulfu... 50 3e-05
UniRef50_Q97AP2 Cluster: Folylpolyglutamate synthase; n=2; Therm... 50 3e-05
UniRef50_Q67SJ1 Cluster: Folylpolyglutamate synthase; n=1; Symbi... 50 4e-05
UniRef50_Q2HAU4 Cluster: Putative uncharacterized protein; n=1; ... 50 4e-05
UniRef50_Q49Y95 Cluster: Folylpolyglutamate synthase; n=16; Stap... 50 5e-05
UniRef50_A1WY03 Cluster: FolC bifunctional protein; n=1; Halorho... 50 5e-05
UniRef50_A1CXV3 Cluster: Dihydrofolate synthetase Fol3; n=11; Pe... 50 5e-05
UniRef50_Q1VHQ7 Cluster: FolC bifunctional protein; n=1; Psychro... 49 7e-05
UniRef50_Q03EP1 Cluster: Folylpolyglutamate synthase; n=1; Pedio... 49 7e-05
UniRef50_Q6BKI0 Cluster: Debaryomyces hansenii chromosome F of s... 49 7e-05
UniRef50_Q5V5Y3 Cluster: Dihydropteroate synthase; n=1; Haloarcu... 49 7e-05
UniRef50_UPI0000E88026 Cluster: folylpolyglutamate synthetase; n... 49 9e-05
UniRef50_Q4UH02 Cluster: Dihydrofolate synthase/folylpolyglutama... 49 9e-05
UniRef50_Q59S44 Cluster: Putative uncharacterized protein; n=2; ... 49 9e-05
UniRef50_Q2VIK1 Cluster: Dihydrofolate synthase; n=1; Pneumocyst... 49 9e-05
UniRef50_Q2HCU3 Cluster: Putative uncharacterized protein; n=1; ... 49 9e-05
UniRef50_A5DAQ6 Cluster: Putative uncharacterized protein; n=1; ... 49 9e-05
UniRef50_Q0VPJ2 Cluster: Folylpolyglutamate synthase / dihydrofo... 48 1e-04
UniRef50_Q5FRN0 Cluster: Folylpolyglutamate synthase / dihydrofo... 48 2e-04
UniRef50_A7HJX6 Cluster: FolC bifunctional protein; n=2; Thermot... 48 2e-04
UniRef50_Q7M927 Cluster: FOLYLPOLYGLUTAMATE SYNTHASE; n=1; Wolin... 48 2e-04
UniRef50_A0Z5L0 Cluster: Folylpolyglutamate synthase/dihydrofola... 48 2e-04
UniRef50_Q9UTD0 Cluster: Folylpolyglutamate synthase; n=1; Schiz... 48 2e-04
UniRef50_Q72J06 Cluster: Folylpolyglutamate synthase/dihydrofola... 47 3e-04
UniRef50_Q8F8C1 Cluster: FolC bifunctional protein; n=4; Leptosp... 47 4e-04
UniRef50_Q30Q85 Cluster: Folylpolyglutamate synthetase; n=1; Thi... 46 6e-04
UniRef50_A5GRK4 Cluster: FolC bifunctional protein; n=2; Synecho... 46 6e-04
UniRef50_Q7NL38 Cluster: Folyl-polyglutamate synthetase; n=1; Gl... 45 0.001
UniRef50_Q38XD0 Cluster: Putative polylpolyglutamate synthase; n... 45 0.001
UniRef50_A7RZ44 Cluster: Predicted protein; n=1; Nematostella ve... 45 0.001
UniRef50_Q2SR89 Cluster: Folate synthetase-polyglutamyl folate s... 44 0.003
UniRef50_UPI000023EB67 Cluster: hypothetical protein FG10379.1; ... 44 0.003
UniRef50_A6R8F1 Cluster: Predicted protein; n=1; Ajellomyces cap... 44 0.003
UniRef50_A4QWG8 Cluster: Putative uncharacterized protein; n=1; ... 43 0.004
UniRef50_Q14PS6 Cluster: Hypothetical folylpolyglutamate synthas... 42 0.008
UniRef50_P15925 Cluster: Folylpolyglutamate synthase; n=2; Lacto... 42 0.013
UniRef50_Q3AV81 Cluster: Folylpolyglutamate synthetase; n=11; Cy... 41 0.023
UniRef50_Q7VIZ0 Cluster: Folylpolyglutamate synthase; n=1; Helic... 40 0.041
UniRef50_Q2A2S3 Cluster: FolC Bifunctional protein; n=11; Franci... 39 0.072
UniRef50_Q47XK6 Cluster: FolC bifunctional protein; n=1; Colwell... 38 0.17
UniRef50_A0L5N6 Cluster: UDP-N-acetylmuramyl-tripeptide syntheta... 38 0.17
UniRef50_A5K880 Cluster: Putative uncharacterized protein; n=1; ... 38 0.17
UniRef50_P36001 Cluster: Probable folylpolyglutamate synthase; n... 37 0.38
UniRef50_Q4SC04 Cluster: Chromosome 14 SCAF14660, whole genome s... 36 0.67
UniRef50_Q4AN71 Cluster: Putative uncharacterized protein precur... 36 0.67
UniRef50_Q1IKG5 Cluster: UDP-N-acetylmuramoylalanyl-D-glutamate-... 34 2.0
UniRef50_Q223U9 Cluster: Putative uncharacterized protein; n=3; ... 34 2.0
UniRef50_Q1FLS0 Cluster: UDP-N-acetylmuramyl-tripeptide syntheta... 34 2.7
UniRef50_Q60A31 Cluster: Thiol:disulfide interchange protein, Ds... 33 3.6
UniRef50_A7QCD4 Cluster: Chromosome undetermined scaffold_77, wh... 33 3.6
UniRef50_Q22BU4 Cluster: Putative uncharacterized protein; n=1; ... 33 3.6
UniRef50_O83903 Cluster: UDP-N-acetylmuramoylalanyl-D-glutamate-... 33 3.6
UniRef50_Q894B7 Cluster: UDP-N-acetylmuramoylalanyl-D-glutamate-... 33 3.6
UniRef50_Q8KA84 Cluster: DNA polymerase family B protein; n=11; ... 33 4.7
UniRef50_Q83MU4 Cluster: UDP-N-acetylmuramyl tripeptide synthase... 33 4.7
UniRef50_Q390X5 Cluster: Two component transcriptional regulator... 33 4.7
UniRef50_Q96LE4 Cluster: Folylpolyglutamate synthetase mitochond... 33 4.7
UniRef50_Q4SSX9 Cluster: Chromosome 8 SCAF14344, whole genome sh... 33 6.2
UniRef50_Q07Y43 Cluster: UDP-N-acetylmuramate precursor; n=3; Al... 33 6.2
UniRef50_A7K108 Cluster: Methyl-accepting chemotaxis protein; n=... 33 6.2
UniRef50_Q3AAE1 Cluster: UDP-N-acetylmuramoylalanyl-D-glutamyl-2... 32 8.2
UniRef50_Q0J7Q9 Cluster: Os08g0170700 protein; n=9; Oryza sativa... 32 8.2
UniRef50_Q5JWR5 Cluster: Protein dopey-1; n=25; Deuterostomia|Re... 32 8.2
>UniRef50_UPI00015B4A18 Cluster: PREDICTED: similar to FPGS protein,
partial; n=1; Nasonia vitripennis|Rep: PREDICTED:
similar to FPGS protein, partial - Nasonia vitripennis
Length = 571
Score = 137 bits (331), Expect = 2e-31
Identities = 67/138 (48%), Positives = 96/138 (69%)
Frame = +3
Query: 156 VKSNYEDAVHKLNKLQSNKSTIDQIRKDLRTGKRCTNLEDMERYLFRTGVTLTKLDELSV 335
+++ + +AV LN LQSN + I R+ T T L++ ++YL R+G+TL +LD+LSV
Sbjct: 39 LQAYHPEAVRSLNSLQSNAAYIKVARQLSPTEN--TTLQETKKYLIRSGLTLEQLDQLSV 96
Query: 336 IHVAGTKGKGSTSAMCDSILRHHGFRTGFFSSPHLIAVRERIRLDGKIVSEEKFAQHFHR 515
IHVAGTKGKGST A ++ILR HGFRTGF+SSPHLI+VRER R++G+ ++E +F++HF
Sbjct: 97 IHVAGTKGKGSTCAFTEAILREHGFRTGFYSSPHLISVRERFRINGRPINELEFSRHFWH 156
Query: 516 VYNXXXXXXXXXXXXPKY 569
V+N P+Y
Sbjct: 157 VFNILQQKKETDSDMPQY 174
>UniRef50_UPI0000DB6E21 Cluster: PREDICTED: similar to
folylpolyglutamate synthase; n=1; Apis mellifera|Rep:
PREDICTED: similar to folylpolyglutamate synthase - Apis
mellifera
Length = 440
Score = 135 bits (327), Expect = 6e-31
Identities = 71/147 (48%), Positives = 91/147 (61%), Gaps = 1/147 (0%)
Frame = +3
Query: 132 NKLVRMYSVK-SNYEDAVHKLNKLQSNKSTIDQIRKDLRTGKRCTNLEDMERYLFRTGVT 308
N ++ Y S+YE A+ KL LQSN + + K+ L D +YL R+G+T
Sbjct: 3 NTFIKRYVCNTSSYEAAIKKLCGLQSNSTYLKLATKNNSQTSDTYKLLDTIKYLVRSGIT 62
Query: 309 LTKLDELSVIHVAGTKGKGSTSAMCDSILRHHGFRTGFFSSPHLIAVRERIRLDGKIVSE 488
L KLD LSVIHVAGTKGKGST A ++ILR HGF+TGFFSSPHLI+ RERIRL+G+ +SE
Sbjct: 63 LEKLDTLSVIHVAGTKGKGSTCAYTEAILREHGFKTGFFSSPHLISARERIRLNGQPISE 122
Query: 489 EKFAQHFHRVYNXXXXXXXXXXXXPKY 569
F Q+F ++Y P Y
Sbjct: 123 MHFTQNFWKIYKKLEDTREYESDMPAY 149
>UniRef50_UPI0000E4A2B9 Cluster: PREDICTED: similar to
Folylpolyglutamate synthase; n=1; Strongylocentrotus
purpuratus|Rep: PREDICTED: similar to Folylpolyglutamate
synthase - Strongylocentrotus purpuratus
Length = 647
Score = 133 bits (322), Expect = 2e-30
Identities = 65/119 (54%), Positives = 87/119 (73%)
Frame = +3
Query: 168 YEDAVHKLNKLQSNKSTIDQIRKDLRTGKRCTNLEDMERYLFRTGVTLTKLDELSVIHVA 347
Y++A+ KLN LQSN T+D+IRK+ G N+ D+ R G++L +LDELS IHVA
Sbjct: 47 YQEAIRKLNTLQSNAKTLDEIRKNRDMGAY-KNIPDVIDGATRVGISLERLDELSCIHVA 105
Query: 348 GTKGKGSTSAMCDSILRHHGFRTGFFSSPHLIAVRERIRLDGKIVSEEKFAQHFHRVYN 524
GTKGKGS A +SILR GF+TGF+SSPHL+ VRERIR++G+ + +E FA++F VYN
Sbjct: 106 GTKGKGSVCAFTESILRASGFKTGFYSSPHLVEVRERIRINGQPLPKEDFAKNFFTVYN 164
>UniRef50_Q5JU23 Cluster: Folylpolyglutamate synthase; n=2; Homo
sapiens|Rep: Folylpolyglutamate synthase - Homo sapiens
(Human)
Length = 375
Score = 129 bits (311), Expect = 5e-29
Identities = 61/119 (51%), Positives = 86/119 (72%)
Frame = +3
Query: 168 YEDAVHKLNKLQSNKSTIDQIRKDLRTGKRCTNLEDMERYLFRTGVTLTKLDELSVIHVA 347
Y+DAV LN LQ+N ++Q+++ + G T LE ME YL R+G+ + LD L++IHV
Sbjct: 45 YQDAVRMLNTLQTNAGYLEQVKR--QRGDPQTQLEAMELYLARSGLQVEDLDRLNIIHVT 102
Query: 348 GTKGKGSTSAMCDSILRHHGFRTGFFSSPHLIAVRERIRLDGKIVSEEKFAQHFHRVYN 524
GTKGKGST A + ILR +G +TGFFSSPHL+ VRERIR++G+ +S E F ++F R+Y+
Sbjct: 103 GTKGKGSTCAFTECILRSYGLKTGFFSSPHLVQVRERIRINGQPISPELFTKYFWRLYH 161
>UniRef50_Q05932 Cluster: Folylpolyglutamate synthase, mitochondrial
precursor; n=34; Euteleostomi|Rep: Folylpolyglutamate
synthase, mitochondrial precursor - Homo sapiens (Human)
Length = 587
Score = 129 bits (311), Expect = 5e-29
Identities = 61/119 (51%), Positives = 86/119 (72%)
Frame = +3
Query: 168 YEDAVHKLNKLQSNKSTIDQIRKDLRTGKRCTNLEDMERYLFRTGVTLTKLDELSVIHVA 347
Y+DAV LN LQ+N ++Q+++ + G T LE ME YL R+G+ + LD L++IHV
Sbjct: 45 YQDAVRMLNTLQTNAGYLEQVKR--QRGDPQTQLEAMELYLARSGLQVEDLDRLNIIHVT 102
Query: 348 GTKGKGSTSAMCDSILRHHGFRTGFFSSPHLIAVRERIRLDGKIVSEEKFAQHFHRVYN 524
GTKGKGST A + ILR +G +TGFFSSPHL+ VRERIR++G+ +S E F ++F R+Y+
Sbjct: 103 GTKGKGSTCAFTECILRSYGLKTGFFSSPHLVQVRERIRINGQPISPELFTKYFWRLYH 161
>UniRef50_Q5TSB4 Cluster: ENSANGP00000026850; n=1; Anopheles gambiae
str. PEST|Rep: ENSANGP00000026850 - Anopheles gambiae
str. PEST
Length = 490
Score = 127 bits (307), Expect = 2e-28
Identities = 63/141 (44%), Positives = 91/141 (64%), Gaps = 2/141 (1%)
Frame = +3
Query: 153 SVKSNYEDAVHKLNKLQSNKSTIDQ--IRKDLRTGKRCTNLEDMERYLFRTGVTLTKLDE 326
++ +YE+A+ LN LQSN S + +RK K ++ D +YL R GV++ L++
Sbjct: 9 TLDESYENAISSLNSLQSNSSVLQDSILRKHSEDNK---HINDTLKYLLRIGVSMDHLNQ 65
Query: 327 LSVIHVAGTKGKGSTSAMCDSILRHHGFRTGFFSSPHLIAVRERIRLDGKIVSEEKFAQH 506
L VIHV+GTKGKGST AM +SILR +G+RTGFFSSPHL++V+ER+RL+G +S +KF +
Sbjct: 66 LPVIHVSGTKGKGSTCAMIESILRSNGYRTGFFSSPHLVSVKERVRLNGMPLSSDKFRLY 125
Query: 507 FHRVYNXXXXXXXXXXXXPKY 569
F ++Y P Y
Sbjct: 126 FWKIYKQLLAYREHSRDMPSY 146
>UniRef50_UPI0000D556C6 Cluster: PREDICTED: similar to
Folylpolyglutamate synthase, mitochondrial precursor
(Folylpoly-gamma-glutamate synthetase) (FPGS)
(Tetrahydrofolate synthase)
(Tetrahydrofolylpolyglutamate synthase); n=1; Tribolium
castaneum|Rep: PREDICTED: similar to Folylpolyglutamate
synthase, mitochondrial precursor
(Folylpoly-gamma-glutamate synthetase) (FPGS)
(Tetrahydrofolate synthase)
(Tetrahydrofolylpolyglutamate synthase) - Tribolium
castaneum
Length = 464
Score = 126 bits (304), Expect = 4e-28
Identities = 60/120 (50%), Positives = 82/120 (68%)
Frame = +3
Query: 165 NYEDAVHKLNKLQSNKSTIDQIRKDLRTGKRCTNLEDMERYLFRTGVTLTKLDELSVIHV 344
+Y+ + LN LQ+N I K L L +++YL+R G++L LD+LSVIHV
Sbjct: 8 DYDACIEALNNLQTNAQYIKT--KALTNNHNGDQLTQVKKYLYRAGLSLENLDDLSVIHV 65
Query: 345 AGTKGKGSTSAMCDSILRHHGFRTGFFSSPHLIAVRERIRLDGKIVSEEKFAQHFHRVYN 524
AGTKGKG+T A + ILR HG++TGFFSSPHLI VRERIR++GK +S+ F + F ++YN
Sbjct: 66 AGTKGKGTTCAFTERILREHGYKTGFFSSPHLIEVRERIRINGKPISKPDFVKSFWKIYN 125
>UniRef50_Q9VYL1 Cluster: CG2543-PA; n=4; Sophophora|Rep: CG2543-PA
- Drosophila melanogaster (Fruit fly)
Length = 572
Score = 126 bits (303), Expect = 5e-28
Identities = 61/134 (45%), Positives = 87/134 (64%)
Frame = +3
Query: 168 YEDAVHKLNKLQSNKSTIDQIRKDLRTGKRCTNLEDMERYLFRTGVTLTKLDELSVIHVA 347
+E A+ +LN LQSN + I ++ + R D +YL R+G+ L +++LS IHVA
Sbjct: 96 FELAIKQLNSLQSNDAAI----RNSMSNSRVDTKADTIKYLERSGLPLETVEQLSFIHVA 151
Query: 348 GTKGKGSTSAMCDSILRHHGFRTGFFSSPHLIAVRERIRLDGKIVSEEKFAQHFHRVYNX 527
GTKGKGST A+ +S+LRH GFRTGFFSSPH++ ERIR+DG+++S++KF + F +VYN
Sbjct: 152 GTKGKGSTCALTESLLRHQGFRTGFFSSPHILFTNERIRIDGQLLSKDKFTEQFWKVYNR 211
Query: 528 XXXXXXXXXXXPKY 569
P Y
Sbjct: 212 LWDLREHDHDMPAY 225
>UniRef50_Q09509 Cluster: Putative folylpolyglutamate synthase; n=3;
Caenorhabditis elegans|Rep: Putative folylpolyglutamate
synthase - Caenorhabditis elegans
Length = 510
Score = 120 bits (290), Expect = 2e-26
Identities = 63/130 (48%), Positives = 87/130 (66%), Gaps = 2/130 (1%)
Frame = +3
Query: 141 VRMYSVKSN--YEDAVHKLNKLQSNKSTIDQIRKDLRTGKRCTNLEDMERYLFRTGVTLT 314
+RM S K+ YE++V LN LQSN +TI ++R R + NL +YL ++
Sbjct: 25 LRMSSEKAVPCYEESVRLLNGLQSNAATIKKLRVQ-RENLQAINLPQCRKYLESLNISAE 83
Query: 315 KLDELSVIHVAGTKGKGSTSAMCDSILRHHGFRTGFFSSPHLIAVRERIRLDGKIVSEEK 494
L+ L++IHV+GTKGKGS A +SILR G RTGF+SSPHL+ VRERI++DG+ VSE+
Sbjct: 84 DLNALNIIHVSGTKGKGSACAFVESILRSQGLRTGFYSSPHLVHVRERIQVDGQPVSEQM 143
Query: 495 FAQHFHRVYN 524
FA+ F VY+
Sbjct: 144 FAEEFFHVYD 153
>UniRef50_Q4THS1 Cluster: Chromosome undetermined SCAF2726, whole
genome shotgun sequence; n=1; Tetraodon
nigroviridis|Rep: Chromosome undetermined SCAF2726,
whole genome shotgun sequence - Tetraodon nigroviridis
(Green puffer)
Length = 171
Score = 111 bits (267), Expect = 1e-23
Identities = 64/139 (46%), Positives = 89/139 (64%), Gaps = 22/139 (15%)
Frame = +3
Query: 171 EDAVHKLNKLQSNKSTIDQIRKDLRTGKRCTNLEDMERYLFRTGVTLT------------ 314
+DAV LN LQ+N S ++Q+R++ R R L+ ME +L R G+T++
Sbjct: 1 QDAVCTLNTLQTNASCLEQVRRE-RNHPRL-QLQAMEGFLERAGLTVSGRGGGRPAGPHR 58
Query: 315 ----------KLDELSVIHVAGTKGKGSTSAMCDSILRHHGFRTGFFSSPHLIAVRERIR 464
+LD L++IHV GTKGKGST A + ILR HGFRTGF+SSPHL+ VRERIR
Sbjct: 59 PADASLSKVEQLDHLNIIHVTGTKGKGSTCAFTEHILRSHGFRTGFYSSPHLVQVRERIR 118
Query: 465 LDGKIVSEEKFAQHFHRVY 521
++GK +S+E F ++F +VY
Sbjct: 119 INGKPISKELFTKYFWQVY 137
>UniRef50_Q5KJZ3 Cluster: Tetrahydrofolylpolyglutamate synthase,
putative; n=2; Filobasidiella neoformans|Rep:
Tetrahydrofolylpolyglutamate synthase, putative -
Cryptococcus neoformans (Filobasidiella neoformans)
Length = 497
Score = 109 bits (263), Expect = 3e-23
Identities = 62/134 (46%), Positives = 88/134 (65%), Gaps = 4/134 (2%)
Frame = +3
Query: 135 KLVRMYSVKSNYEDAVHKLNKLQSNKSTIDQIRKDLRTGKRCTN--LEDMERYLFRTGVT 308
+L RM S ++ Y +AV LN QSN +TI+ RK +G R T + +M YL R G
Sbjct: 6 RLFRMASTRT-YAEAVSLLNTCQSNAATIEAFRK---SGGRLTEYAVAEMHDYLRRIGYK 61
Query: 309 LTKLDELSVIHVAGTKGKGSTSAMCDSILRHH--GFRTGFFSSPHLIAVRERIRLDGKIV 482
L+ L+V+H+ GTKGKGSTSA + ILR H G + G ++SPHL AVRERIR++G+ +
Sbjct: 62 PEDLNALNVVHITGTKGKGSTSAFTERILRAHMPGKKVGLYTSPHLCAVRERIRINGEPI 121
Query: 483 SEEKFAQHFHRVYN 524
SE +FA++F V++
Sbjct: 122 SETEFAKYFFEVWD 135
>UniRef50_O13492 Cluster: Folylpolyglutamate synthase; n=5;
Pezizomycotina|Rep: Folylpolyglutamate synthase -
Neurospora crassa
Length = 528
Score = 109 bits (261), Expect = 6e-23
Identities = 64/133 (48%), Positives = 84/133 (63%), Gaps = 7/133 (5%)
Frame = +3
Query: 147 MYSVKSNYEDAVHKLNKLQSNKSTIDQIRK-DLRTGKRCTNLEDMERYLFRTGVTLTKLD 323
M S Y DA+ LN LQ+ + I+ RK +R ++++M YL R G + LD
Sbjct: 35 MASSARTYNDAIDALNSLQTPFAVIEARRKAGIRPDAH--SVKEMRAYLARIGYSSQDLD 92
Query: 324 ELSVIHVAGTKGKGSTSAMCDSIL-RH---HGF--RTGFFSSPHLIAVRERIRLDGKIVS 485
L+++HVAGTKGKG T A DSIL RH HG R G F+SPHLIAVRERIR+D K +S
Sbjct: 93 RLNIVHVAGTKGKGGTCAFVDSILTRHQRTHGIPRRIGLFTSPHLIAVRERIRIDSKPIS 152
Query: 486 EEKFAQHFHRVYN 524
EE FA++F V++
Sbjct: 153 EELFARYFFEVWD 165
>UniRef50_Q54CY5 Cluster: Tetrahydrofolylpolyglutamate synthase;
n=1; Dictyostelium discoideum AX4|Rep:
Tetrahydrofolylpolyglutamate synthase - Dictyostelium
discoideum AX4
Length = 626
Score = 107 bits (256), Expect = 2e-22
Identities = 58/125 (46%), Positives = 84/125 (67%), Gaps = 4/125 (3%)
Frame = +3
Query: 147 MYSVKS-NYEDAVHKLNKLQSNKSTIDQIRKDLRTGKRCTN---LEDMERYLFRTGVTLT 314
+YS K +YE+AV+ L LQSN++ I K+ R K + +E+M Y + L
Sbjct: 73 LYSPKDRSYEEAVNALLTLQSNQTVIISWTKERRDNKEESAKFLMEEMRNYCKTLSIDL- 131
Query: 315 KLDELSVIHVAGTKGKGSTSAMCDSILRHHGFRTGFFSSPHLIAVRERIRLDGKIVSEEK 494
+ S+IHVAGTKGKGST A+ +SI+R GF TG F+SPHLI+ RERIR++G+++S+E
Sbjct: 132 --ERESIIHVAGTKGKGSTCAITESIIREQGFSTGLFTSPHLISPRERIRINGEMISKEM 189
Query: 495 FAQHF 509
F+Q+F
Sbjct: 190 FSQYF 194
>UniRef50_Q9Y893 Cluster: Folylpolyglutamate synthase; n=7;
Saccharomycetales|Rep: Folylpolyglutamate synthase -
Candida albicans (Yeast)
Length = 514
Score = 102 bits (245), Expect = 5e-21
Identities = 48/126 (38%), Positives = 86/126 (68%), Gaps = 2/126 (1%)
Frame = +3
Query: 153 SVKSNYEDAVHKLNKLQSNKSTIDQIRK-DLRTGKRCTNLEDMERYLFRTGVTLTKLDEL 329
+++ Y+DA++ LN LQSN ++I+ +K + ++ ++ + R G T T ++L
Sbjct: 13 NLQRTYKDAINALNSLQSNFASIEATKKLGPSVNRNELSINEVHEFTKRLGYTPTDFNKL 72
Query: 330 SVIHVAGTKGKGSTSAMCDSILRHHGF-RTGFFSSPHLIAVRERIRLDGKIVSEEKFAQH 506
++IH+ GTKGKGST A +SIL+ + + G ++SPHL +VRERIR++G+ +++EKFA++
Sbjct: 73 NIIHITGTKGKGSTCAFTESILKQYTISKIGLYTSPHLKSVRERIRINGQPINQEKFAKY 132
Query: 507 FHRVYN 524
F V++
Sbjct: 133 FFEVWD 138
>UniRef50_Q8W038 Cluster: Folylpolyglutamate synthetase,
mitochondrial isoform; n=6; core eudicotyledons|Rep:
Folylpolyglutamate synthetase, mitochondrial isoform -
Arabidopsis thaliana (Mouse-ear cress)
Length = 625
Score = 101 bits (241), Expect = 2e-20
Identities = 58/116 (50%), Positives = 75/116 (64%)
Frame = +3
Query: 162 SNYEDAVHKLNKLQSNKSTIDQIRKDLRTGKRCTNLEDMERYLFRTGVTLTKLDELSVIH 341
S+Y+DA+ L+ L S ++ D+ G R LE + YL + K+ EL VIH
Sbjct: 81 SSYDDAMEALSTLISRRNRGDRTPTK---GNR-DKLEQVVTYLKILDLE-DKIKELKVIH 135
Query: 342 VAGTKGKGSTSAMCDSILRHHGFRTGFFSSPHLIAVRERIRLDGKIVSEEKFAQHF 509
VAGTKGKGST ++ILR+ GFRTG F+SPHLI VRER R+DG +SEEKF Q+F
Sbjct: 136 VAGTKGKGSTCVFSEAILRNCGFRTGMFTSPHLIDVRERFRIDGLDISEEKFLQYF 191
>UniRef50_Q08645 Cluster: Folylpolyglutamate synthase; n=7;
Saccharomycetales|Rep: Folylpolyglutamate synthase -
Saccharomyces cerevisiae (Baker's yeast)
Length = 548
Score = 100 bits (239), Expect = 3e-20
Identities = 57/141 (40%), Positives = 86/141 (60%), Gaps = 3/141 (2%)
Frame = +3
Query: 111 LYRSYLVNKLVRMYSVKSNYEDAVHKLNKLQSNKSTIDQIRKDLRTGKRCTNLEDMERYL 290
L+ ++ +RM V Y DAV LN LQSN + I IR+ K L +M +
Sbjct: 51 LFDLMIIKNPLRM--VGKTYRDAVTALNSLQSNYANIMAIRQT-GDRKNTMTLLEMHEWS 107
Query: 291 FRTGVTLTKLDELSVIHVAGTKGKGSTSAMCDSILRHHGF---RTGFFSSPHLIAVRERI 461
R G + + ++L+++H+ GTKGKGST+A SIL + R G ++SPHL +VRERI
Sbjct: 108 RRIGYSASDFNKLNIVHITGTKGKGSTAAFTSSILGQYKEQLPRIGLYTSPHLKSVRERI 167
Query: 462 RLDGKIVSEEKFAQHFHRVYN 524
R++G+ +SEEKFA++F V++
Sbjct: 168 RINGEPISEEKFAKYFFEVWD 188
>UniRef50_Q4P7Z1 Cluster: Putative uncharacterized protein; n=1;
Ustilago maydis|Rep: Putative uncharacterized protein -
Ustilago maydis (Smut fungus)
Length = 553
Score = 97.5 bits (232), Expect = 2e-19
Identities = 54/128 (42%), Positives = 82/128 (64%), Gaps = 9/128 (7%)
Frame = +3
Query: 168 YEDAVHKLNKLQSNKSTIDQIRKDLRTGKRCTN--LEDMERYLFRTGVTLTKLDELSVIH 341
Y+DA+ LN LQSN +TI+ +RK +G R + + +M YL R G T + L+ L+VIH
Sbjct: 18 YDDAIDALNSLQSNAATIEALRK---SGGRLLDFAIPEMVEYLERIGYTTSDLNRLNVIH 74
Query: 342 VAGTKGKGSTSAMCDSIL-------RHHGFRTGFFSSPHLIAVRERIRLDGKIVSEEKFA 500
+ GTKGKGST A DS+L + G ++SPH+ +VRERIR++G+ V+ E F
Sbjct: 75 ITGTKGKGSTCAFVDSLLGQLTPVNASAKPKVGLYTSPHMTSVRERIRINGQPVTHELFT 134
Query: 501 QHFHRVYN 524
++F +V++
Sbjct: 135 KYFWQVWD 142
>UniRef50_Q2UUH9 Cluster: Folylpolyglutamate synthase; n=2;
Eurotiomycetidae|Rep: Folylpolyglutamate synthase -
Aspergillus oryzae
Length = 522
Score = 97.1 bits (231), Expect = 3e-19
Identities = 55/129 (42%), Positives = 81/129 (62%), Gaps = 7/129 (5%)
Frame = +3
Query: 159 KSNYEDAVHKLNKLQSN-KSTIDQIRKDLRTGKRCTNLEDMERYLFRTGVTLTKLDELSV 335
K +Y DAV KLN QS K+ ++ RTG LE M++++ R G + D L++
Sbjct: 34 KPSYHDAVEKLNSTQSGYKALLEGKGLGRRTGVPL--LEQMQQWVRRVGYETSDFDRLNI 91
Query: 336 IHVAGTKGKGSTSAMCDSIL----RHHGF--RTGFFSSPHLIAVRERIRLDGKIVSEEKF 497
+HVAGTKGKGST A +SIL R G + G ++SPHL+ VRERI+++ + +SEEKF
Sbjct: 92 VHVAGTKGKGSTCAFVNSILQCYNRSIGLPRKVGLYTSPHLVTVRERIQINSEPISEEKF 151
Query: 498 AQHFHRVYN 524
++F V++
Sbjct: 152 TKYFFEVWD 160
>UniRef50_Q8W040 Cluster: Folylpolyglutamate synthetase,
chloroplastic isoform; n=5; Magnoliophyta|Rep:
Folylpolyglutamate synthetase, chloroplastic isoform -
Arabidopsis thaliana (Mouse-ear cress)
Length = 571
Score = 96.3 bits (229), Expect = 4e-19
Identities = 58/135 (42%), Positives = 77/135 (57%)
Frame = +3
Query: 165 NYEDAVHKLNKLQSNKSTIDQIRKDLRTGKRCTNLEDMERYLFRTGVTLTKLDELSVIHV 344
+YE+A+ L+ L + +S D+ K G R + D + L L +++VIHV
Sbjct: 66 SYEEALAALSSLITKRSRADKSNK----GDRFELVFDYLKLLDLEEDIL----KMNVIHV 117
Query: 345 AGTKGKGSTSAMCDSILRHHGFRTGFFSSPHLIAVRERIRLDGKIVSEEKFAQHFHRVYN 524
AGTKGKGST +SI+R++GFRTG F+SPHLI VRER RLDG +SEEKF +F YN
Sbjct: 118 AGTKGKGSTCTFTESIIRNYGFRTGLFTSPHLIDVRERFRLDGVDISEEKFLGYFWWCYN 177
Query: 525 XXXXXXXXXXXXPKY 569
P Y
Sbjct: 178 RLKERTNEEIPMPTY 192
>UniRef50_UPI0000E484D2 Cluster: PREDICTED: similar to
Folylpolyglutamate synthase; n=4; Strongylocentrotus
purpuratus|Rep: PREDICTED: similar to Folylpolyglutamate
synthase - Strongylocentrotus purpuratus
Length = 562
Score = 89.0 bits (211), Expect = 7e-17
Identities = 47/105 (44%), Positives = 65/105 (61%)
Frame = +3
Query: 192 NKLQSNKSTIDQIRKDLRTGKRCTNLEDMERYLFRTGVTLTKLDELSVIHVAGTKGKGST 371
N Q N+ +D++RK L + D L R G+T LD LS IHVAGTKGKGST
Sbjct: 38 NDRQENRPDLDELRKFL--------ISDYRICLERLGITRKDLDALSCIHVAGTKGKGST 89
Query: 372 SAMCDSILRHHGFRTGFFSSPHLIAVRERIRLDGKIVSEEKFAQH 506
AM + ILR +G++TG SSP L+ +RER+R++G VS + ++
Sbjct: 90 CAMTERILRTYGYKTGIISSPPLLEIRERVRINGAPVSRAMYGRY 134
>UniRef50_Q96G81 Cluster: Folylpolyglutamate synthase; n=2;
Eutheria|Rep: Folylpolyglutamate synthase - Homo sapiens
(Human)
Length = 174
Score = 89.0 bits (211), Expect = 7e-17
Identities = 43/86 (50%), Positives = 59/86 (68%)
Frame = +3
Query: 168 YEDAVHKLNKLQSNKSTIDQIRKDLRTGKRCTNLEDMERYLFRTGVTLTKLDELSVIHVA 347
Y+DAV LN LQ+N ++Q+++ + G T LE ME YL R+G+ + LD L++IHV
Sbjct: 45 YQDAVRMLNTLQTNAGYLEQVKR--QRGDPQTQLEAMELYLARSGLQVEDLDRLNIIHVT 102
Query: 348 GTKGKGSTSAMCDSILRHHGFRTGFF 425
GTKGKGST A + ILR +G +TGFF
Sbjct: 103 GTKGKGSTCAFTECILRSYGLKTGFF 128
>UniRef50_A7PIN0 Cluster: Chromosome chr13 scaffold_17, whole genome
shotgun sequence; n=1; Vitis vinifera|Rep: Chromosome
chr13 scaffold_17, whole genome shotgun sequence - Vitis
vinifera (Grape)
Length = 832
Score = 88.2 bits (209), Expect = 1e-16
Identities = 40/64 (62%), Positives = 49/64 (76%)
Frame = +3
Query: 318 LDELSVIHVAGTKGKGSTSAMCDSILRHHGFRTGFFSSPHLIAVRERIRLDGKIVSEEKF 497
+ ++ +IHVAGTKGKGST +SILR+ GFRTG F+SPHLI VRER RLDG + EEKF
Sbjct: 372 ISKMKIIHVAGTKGKGSTCTFTESILRNCGFRTGLFTSPHLIDVRERFRLDGVEICEEKF 431
Query: 498 AQHF 509
+F
Sbjct: 432 LAYF 435
>UniRef50_A4S2I3 Cluster: Predicted protein; n=2; Ostreococcus|Rep:
Predicted protein - Ostreococcus lucimarinus CCE9901
Length = 486
Score = 86.6 bits (205), Expect = 4e-16
Identities = 42/78 (53%), Positives = 55/78 (70%)
Frame = +3
Query: 276 MERYLFRTGVTLTKLDELSVIHVAGTKGKGSTSAMCDSILRHHGFRTGFFSSPHLIAVRE 455
+E Y+ R + ++D L V+HVAGTKGKGST AM + +LR G R G F+SPHL+ VRE
Sbjct: 39 LETYVSRLDLR-GRVDALDVVHVAGTKGKGSTCAMVEGMLRASGTRVGTFTSPHLMDVRE 97
Query: 456 RIRLDGKIVSEEKFAQHF 509
R R+DG +V EE FA+ F
Sbjct: 98 RFRIDGAMVDEETFAREF 115
>UniRef50_Q9M059 Cluster: Tetrahydrofolylpolyglutamate synthase-like
protein; n=9; Magnoliophyta|Rep:
Tetrahydrofolylpolyglutamate synthase-like protein -
Arabidopsis thaliana (Mouse-ear cress)
Length = 498
Score = 85.8 bits (203), Expect = 6e-16
Identities = 38/64 (59%), Positives = 49/64 (76%)
Frame = +3
Query: 318 LDELSVIHVAGTKGKGSTSAMCDSILRHHGFRTGFFSSPHLIAVRERIRLDGKIVSEEKF 497
+ ++ +IHVAGTKGKGST +SILR +G RTG F+SPHLI VRER RL+G +S+EKF
Sbjct: 55 VSQMKIIHVAGTKGKGSTCTFAESILRCYGLRTGLFTSPHLIDVRERFRLNGIEISQEKF 114
Query: 498 AQHF 509
+F
Sbjct: 115 VNYF 118
>UniRef50_Q2UGP7 Cluster: Folylpolyglutamate synthase; n=10;
Pezizomycotina|Rep: Folylpolyglutamate synthase -
Aspergillus oryzae
Length = 561
Score = 85.8 bits (203), Expect = 6e-16
Identities = 56/157 (35%), Positives = 85/157 (54%), Gaps = 19/157 (12%)
Frame = +3
Query: 111 LYRSYLVNKLVRMYS----VKSNYEDAVHKLNKLQSNKSTIDQIRKDL-RTGKRCTNLED 275
++ Y N + R S + NYE A+ LN LQ+N + + Q+R+ R +L +
Sbjct: 23 IHTLYTYNSIRRFSSHPARMSRNYEAAITALNSLQTNFAVVQQLRESGDRRQMNLRSLPE 82
Query: 276 MERYLFRTGVTLTKLDELSVIHVAGTKGKGSTSAMCDSILRHHGF--------------R 413
+L R G + L+ L+ +HVAGTKGKGSTSA SIL + +
Sbjct: 83 TIEWLRRIGYQPSDLNRLNPVHVAGTKGKGSTSAFISSILSQYTSPVPSESNDSAPRLKK 142
Query: 414 TGFFSSPHLIAVRERIRLDGKIVSEEKFAQHFHRVYN 524
G ++SPHL RERI+++G +SEEKFA++F V++
Sbjct: 143 VGLYTSPHLRFARERIQINGAPLSEEKFARYFFEVWD 179
>UniRef50_O74742 Cluster: Probable folylpolyglutamate synthase; n=1;
Schizosaccharomyces pombe|Rep: Probable
folylpolyglutamate synthase - Schizosaccharomyces pombe
(Fission yeast)
Length = 505
Score = 85.8 bits (203), Expect = 6e-16
Identities = 56/156 (35%), Positives = 84/156 (53%), Gaps = 8/156 (5%)
Frame = +3
Query: 126 LVNKLVRMYSVKSNYEDAVHKLNKLQSNKSTIDQIRKDLRTGKRCTNLEDMERYLFRTGV 305
L + + M +E A+++LN LQSN ++ +RK + + +E M +L G
Sbjct: 13 LKSSRIGMNPQTKTFEGAINRLNSLQSNAKVLEVLRKRGKIPNDQSMVE-MRHWLRCIGY 71
Query: 306 TLTKLDELSVIHVAGTKGKGSTSAMCDSILRH---HGFRT-----GFFSSPHLIAVRERI 461
+ L+ L+VIHVAGTKGKGST A SIL+ G R+ G ++SPHL +V ERI
Sbjct: 72 QPSDLNRLNVIHVAGTKGKGSTCAFTSSILQQIQKSGERSIPKCIGMYTSPHLRSVCERI 131
Query: 462 RLDGKIVSEEKFAQHFHRVYNXXXXXXXXXXXXPKY 569
+L+GK +S+E F ++F V+ P Y
Sbjct: 132 QLNGKPISQELFTKYFFDVWERLENAVGSDSEKPMY 167
>UniRef50_Q9VQW0 Cluster: CG31773-PA; n=1; Drosophila
melanogaster|Rep: CG31773-PA - Drosophila melanogaster
(Fruit fly)
Length = 758
Score = 85.0 bits (201), Expect = 1e-15
Identities = 45/117 (38%), Positives = 69/117 (58%)
Frame = +3
Query: 168 YEDAVHKLNKLQSNKSTIDQIRKDLRTGKRCTNLEDMERYLFRTGVTLTKLDELSVIHVA 347
Y DA+ +LN Q + T + ++ +E L ++G+T L + VI VA
Sbjct: 276 YLDAIKQLNSYQVLEPTSGRATTKSSRKEQDPVIEQTLECLEKSGLTKKDLKAIPVIQVA 335
Query: 348 GTKGKGSTSAMCDSILRHHGFRTGFFSSPHLIAVRERIRLDGKIVSEEKFAQHFHRV 518
G+KG+GST A+ +SILR HG +TG SSPHL ERIR+DG+ +S+ +F + F ++
Sbjct: 336 GSKGRGSTCAIVESILRCHGVKTGVLSSPHLFLTSERIRIDGEPLSDVQFTELFWKI 392
>UniRef50_A4RLF6 Cluster: Putative uncharacterized protein; n=1;
Magnaporthe grisea|Rep: Putative uncharacterized protein
- Magnaporthe grisea (Rice blast fungus) (Pyricularia
grisea)
Length = 553
Score = 83.4 bits (197), Expect = 3e-15
Identities = 50/124 (40%), Positives = 73/124 (58%), Gaps = 6/124 (4%)
Frame = +3
Query: 171 EDAVHKLNKLQSNKSTIDQIRKDLRTGKRCTNLEDMERYLFRTGVTLTKLDELSVIHVAG 350
+DA+ LN LQ+ + Q R + + +M L R G + LD L+++HVAG
Sbjct: 40 QDAIDLLNTLQT-PFKVFQARVAAGVRPDASFMTEMRSCLARIGHSPRDLDRLNIVHVAG 98
Query: 351 TKGKGSTSAMCDSILRH----HGF--RTGFFSSPHLIAVRERIRLDGKIVSEEKFAQHFH 512
TKGKG+ A DSIL HG + G +SPHLI+VRERIR++ + VSE+ FA++F
Sbjct: 99 TKGKGTVCAYVDSILNRWRASHGVPGKLGLLTSPHLISVRERIRINSEPVSEDLFAKYFF 158
Query: 513 RVYN 524
V++
Sbjct: 159 EVWD 162
>UniRef50_UPI0000587E85 Cluster: PREDICTED: similar to
Folylpolyglutamate synthase; n=1; Strongylocentrotus
purpuratus|Rep: PREDICTED: similar to Folylpolyglutamate
synthase - Strongylocentrotus purpuratus
Length = 520
Score = 81.8 bits (193), Expect = 1e-14
Identities = 39/79 (49%), Positives = 53/79 (67%)
Frame = +3
Query: 270 EDMERYLFRTGVTLTKLDELSVIHVAGTKGKGSTSAMCDSILRHHGFRTGFFSSPHLIAV 449
+D+ +L R G+ LD LS+IHV GTKGKGST A ++IL G++TG SSP LI +
Sbjct: 42 QDVLIFLERVGIGRDVLDGLSIIHVTGTKGKGSTCAFVENILETCGYKTGLLSSPSLIEI 101
Query: 450 RERIRLDGKIVSEEKFAQH 506
RERIR+ G + KFA++
Sbjct: 102 RERIRIGGTYLPRRKFAEY 120
>UniRef50_A6R4T6 Cluster: Putative uncharacterized protein; n=2;
Ajellomyces capsulatus NAm1|Rep: Putative
uncharacterized protein - Ajellomyces capsulatus NAm1
Length = 452
Score = 81.0 bits (191), Expect = 2e-14
Identities = 48/145 (33%), Positives = 79/145 (54%), Gaps = 7/145 (4%)
Frame = +3
Query: 156 VKSNYEDAVHKLNKLQS-NKSTIDQIRKDLRTGKRCTNLEDMERYLFRTGVTLTKLDELS 332
++ NYE A+H+LN ++ K +D +R +DM +L G + + L+
Sbjct: 1 MERNYEGAIHRLNTRRAIAKPNLDDMRGS----------DDMVEWLRLLGHSTGNMSRLN 50
Query: 333 VIHVAGTKGKGSTSAMCDSILRHHGFRTGF------FSSPHLIAVRERIRLDGKIVSEEK 494
VIH+AGTKGKGST A S+L+ HG +G+ ++SPH+ +RERIR++G+ +S++
Sbjct: 51 VIHIAGTKGKGSTCAFIASLLKAHGDDSGYPQKIGLYTSPHIKDIRERIRINGEPISKDL 110
Query: 495 FAQHFHRVYNXXXXXXXXXXXXPKY 569
F F V++ P+Y
Sbjct: 111 FTIRFFEVWDKLPSKATDKLDIPRY 135
>UniRef50_Q4Q1G0 Cluster: Folylpolyglutamate synthetase; n=6;
Trypanosomatidae|Rep: Folylpolyglutamate synthetase -
Leishmania major
Length = 537
Score = 79.4 bits (187), Expect = 5e-14
Identities = 38/90 (42%), Positives = 59/90 (65%), Gaps = 1/90 (1%)
Frame = +3
Query: 243 RTGKRCTN-LEDMERYLFRTGVTLTKLDELSVIHVAGTKGKGSTSAMCDSILRHHGFRTG 419
R RC + E +R++ R G L+ + +HVAGTKGKG+TSA ++L+ +GF+ G
Sbjct: 76 RRPNRCPDGFETTKRFIDRLGFAPI-LERIRFVHVAGTKGKGTTSAYTAALLQAYGFKVG 134
Query: 420 FFSSPHLIAVRERIRLDGKIVSEEKFAQHF 509
F+SPHL +RER +DG+++ E +AQ+F
Sbjct: 135 LFTSPHLTDLRERTVVDGRLLDENAYAQYF 164
>UniRef50_Q16KT7 Cluster: Folylpolyglutamate synthase; n=1; Aedes
aegypti|Rep: Folylpolyglutamate synthase - Aedes aegypti
(Yellowfever mosquito)
Length = 415
Score = 79.0 bits (186), Expect = 7e-14
Identities = 36/73 (49%), Positives = 47/73 (64%)
Frame = +3
Query: 351 TKGKGSTSAMCDSILRHHGFRTGFFSSPHLIAVRERIRLDGKIVSEEKFAQHFHRVYNXX 530
+K GST ++ +SILR HG+RTGFFSSPHL++V ERIRL+G + KFA +F R+YN
Sbjct: 3 SKQNGSTCSLVESILRAHGYRTGFFSSPHLVSVTERIRLNGTPIDSTKFATYFWRIYNRL 62
Query: 531 XXXXXXXXXXPKY 569
P Y
Sbjct: 63 LNSRDHPYDLPAY 75
>UniRef50_A2G107 Cluster: FolC bifunctional protein; n=1;
Trichomonas vaginalis G3|Rep: FolC bifunctional protein
- Trichomonas vaginalis G3
Length = 399
Score = 75.4 bits (177), Expect = 9e-13
Identities = 33/65 (50%), Positives = 47/65 (72%)
Frame = +3
Query: 324 ELSVIHVAGTKGKGSTSAMCDSILRHHGFRTGFFSSPHLIAVRERIRLDGKIVSEEKFAQ 503
E+ I VAGTKGKGST A+ +SILRH G +TG F+SPHL RERI+++G +S +++
Sbjct: 43 EIPSIVVAGTKGKGSTCAVIESILRHSGLKTGLFTSPHLETPRERIKINGVSISGDEYIS 102
Query: 504 HFHRV 518
+H +
Sbjct: 103 SYHNI 107
>UniRef50_A6PUD4 Cluster: FolC bifunctional protein; n=1;
Victivallis vadensis ATCC BAA-548|Rep: FolC bifunctional
protein - Victivallis vadensis ATCC BAA-548
Length = 432
Score = 73.7 bits (173), Expect = 3e-12
Identities = 33/58 (56%), Positives = 42/58 (72%)
Frame = +3
Query: 324 ELSVIHVAGTKGKGSTSAMCDSILRHHGFRTGFFSSPHLIAVRERIRLDGKIVSEEKF 497
+L IH+AGT GKGST AM + LR GF TGF+SSPHLI +RER R++G+ V + F
Sbjct: 38 DLKFIHLAGTNGKGSTGAMLECALRSAGFTTGFYSSPHLIDIRERFRVNGRAVPQGDF 95
>UniRef50_A2QCB5 Cluster: Contig An02c0080, complete genome; n=6;
Trichocomaceae|Rep: Contig An02c0080, complete genome -
Aspergillus niger
Length = 489
Score = 73.3 bits (172), Expect = 4e-12
Identities = 37/93 (39%), Positives = 56/93 (60%), Gaps = 6/93 (6%)
Frame = +3
Query: 264 NLEDMERYLFRTGVTLTKLDELSVIHVAGTKGKGSTSAMCDSILRHHGFRTGF------F 425
+L M +L G + T + L+++HV GTKGKGST SIL HG RTGF +
Sbjct: 46 SLHGMSEWLQILGHSETDVSRLNIVHVTGTKGKGSTCEFTRSILHAHGLRTGFPSKIGLY 105
Query: 426 SSPHLIAVRERIRLDGKIVSEEKFAQHFHRVYN 524
+SPH+ +RERI+++ K V + F ++F V++
Sbjct: 106 TSPHIQCIRERIQINNKPVPKNLFTKYFFEVWD 138
>UniRef50_A5KLT5 Cluster: Putative uncharacterized protein; n=1;
Ruminococcus torques ATCC 27756|Rep: Putative
uncharacterized protein - Ruminococcus torques ATCC
27756
Length = 396
Score = 72.9 bits (171), Expect = 5e-12
Identities = 31/61 (50%), Positives = 44/61 (72%)
Frame = +3
Query: 327 LSVIHVAGTKGKGSTSAMCDSILRHHGFRTGFFSSPHLIAVRERIRLDGKIVSEEKFAQH 506
+ +IHVAGT GKGS A D +LR RTG F+SPHL+ + ERI +DG+++S+E+F +
Sbjct: 1 MRIIHVAGTNGKGSVCAYLDGMLRSEQKRTGLFTSPHLVKINERIVIDGQMISDERFLEV 60
Query: 507 F 509
F
Sbjct: 61 F 61
>UniRef50_A3ESF6 Cluster: Folylpolyglutamate synthase; n=1;
Leptospirillum sp. Group II UBA|Rep: Folylpolyglutamate
synthase - Leptospirillum sp. Group II UBA
Length = 444
Score = 72.5 bits (170), Expect = 6e-12
Identities = 33/66 (50%), Positives = 42/66 (63%)
Frame = +3
Query: 321 DELSVIHVAGTKGKGSTSAMCDSILRHHGFRTGFFSSPHLIAVRERIRLDGKIVSEEKFA 500
D+ I + GT GKGSTS + D I R G RTG F+SPHL+ VRERIR+DG +V + F
Sbjct: 40 DKFPAIQITGTNGKGSTSVILDLIYRRAGLRTGLFTSPHLLDVRERIRIDGTLVETDVFL 99
Query: 501 QHFHRV 518
+ V
Sbjct: 100 EAMQSV 105
>UniRef50_A7EG57 Cluster: Putative uncharacterized protein; n=1;
Sclerotinia sclerotiorum 1980|Rep: Putative
uncharacterized protein - Sclerotinia sclerotiorum 1980
Length = 520
Score = 72.5 bits (170), Expect = 6e-12
Identities = 54/147 (36%), Positives = 78/147 (53%), Gaps = 21/147 (14%)
Frame = +3
Query: 147 MYSVKSNYEDAVHKLNKLQSNKSTIDQIRK---DLRTGKRCTNLEDMERYLFRTGVTLTK 317
M S +Y+DA+ L+ LQSN++ + I K D+ LE + + TG +K
Sbjct: 1 MASKGRSYDDAIALLDTLQSNRTIVSSISKTSEDMNMYAIPEMLEWTRKAGYETG-DFSK 59
Query: 318 LDELSVIHVAGTKGKGSTSAMCDSILRHH-----------------GF-RTGFFSSPHLI 443
L IHVAGTKGKGS AM +ILR + G + G ++SPHL+
Sbjct: 60 RG-LKCIHVAGTKGKGSVCAMIGNILRQYRRKENDVGVVPGDAKRKGLGKIGLYTSPHLM 118
Query: 444 AVRERIRLDGKIVSEEKFAQHFHRVYN 524
VRERIR+DG +SE FA++F +++
Sbjct: 119 TVRERIRIDGSPISERLFARYFFELWD 145
>UniRef50_A6SID8 Cluster: Putative uncharacterized protein; n=1;
Botryotinia fuckeliana B05.10|Rep: Putative
uncharacterized protein - Botryotinia fuckeliana B05.10
Length = 515
Score = 72.5 bits (170), Expect = 6e-12
Identities = 49/146 (33%), Positives = 75/146 (51%), Gaps = 20/146 (13%)
Frame = +3
Query: 147 MYSVKSNYEDAVHKLNKLQSNKSTIDQIRKDLRTGKRCTNLEDMERYLFRTGVTLTKLDE 326
M S +Y+DA+ L+ LQSN++ + I + + +M + + G
Sbjct: 1 MASKGRSYQDAIALLDTLQSNRTIVSSISSTSKD-MNLYAIPEMLEWTRKAGYETKDFSS 59
Query: 327 --LSVIHVAGTKGKGSTSAMCDSILRHHGF------------------RTGFFSSPHLIA 446
L IHVAGTKGKGS AM D+ILR + + G ++SPHL++
Sbjct: 60 RGLKCIHVAGTKGKGSVCAMIDNILRQYRSEESDIGVMPGGTERKALGKIGLYTSPHLMS 119
Query: 447 VRERIRLDGKIVSEEKFAQHFHRVYN 524
VRERIR+DG +SE FA++F +++
Sbjct: 120 VRERIRIDGLPISEPLFARYFFELWD 145
>UniRef50_Q01UR3 Cluster: FolC bifunctional protein; n=1; Solibacter
usitatus Ellin6076|Rep: FolC bifunctional protein -
Solibacter usitatus (strain Ellin6076)
Length = 422
Score = 72.1 bits (169), Expect = 8e-12
Identities = 35/63 (55%), Positives = 44/63 (69%)
Frame = +3
Query: 333 VIHVAGTKGKGSTSAMCDSILRHHGFRTGFFSSPHLIAVRERIRLDGKIVSEEKFAQHFH 512
++HVAGT GKGST AM +S LR G TG F+SPHL ERIR++G VS E+F+ F
Sbjct: 43 IVHVAGTNGKGSTCAMIESGLRASGRSTGLFTSPHLAEPTERIRINGVPVSAERFSAAFD 102
Query: 513 RVY 521
RV+
Sbjct: 103 RVH 105
>UniRef50_A6BCX0 Cluster: Putative uncharacterized protein; n=2;
Clostridiales|Rep: Putative uncharacterized protein -
Dorea longicatena DSM 13814
Length = 446
Score = 72.1 bits (169), Expect = 8e-12
Identities = 39/101 (38%), Positives = 52/101 (51%)
Frame = +3
Query: 267 LEDMERYLFRTGVTLTKLDELSVIHVAGTKGKGSTSAMCDSILRHHGFRTGFFSSPHLIA 446
LE + +L R G + ++HVAGT GKGS A +IL G RTGFF+SPHL++
Sbjct: 32 LEHTKTFLKRLG---NPAADRKIVHVAGTNGKGSVCAYLQAILMAEGKRTGFFTSPHLVS 88
Query: 447 VRERIRLDGKIVSEEKFAQHFHRVYNXXXXXXXXXXXXPKY 569
V ERIR+D + E F + F +V P Y
Sbjct: 89 VNERIRVDNIQIDNETFLKVFRKVLKIVRQMVEDGIEHPSY 129
>UniRef50_Q6DKZ3 Cluster: Dihydrofolate/folylpolyglutamate synthase;
n=1; Toxoplasma gondii|Rep:
Dihydrofolate/folylpolyglutamate synthase - Toxoplasma
gondii
Length = 553
Score = 70.1 bits (164), Expect = 3e-11
Identities = 29/66 (43%), Positives = 45/66 (68%)
Frame = +3
Query: 321 DELSVIHVAGTKGKGSTSAMCDSILRHHGFRTGFFSSPHLIAVRERIRLDGKIVSEEKFA 500
D+ +IHVAGT GKG+T A + L G++ G ++SPH+++ RERIR+D +++ EE
Sbjct: 43 DDYDIIHVAGTNGKGTTCAKLAACLSLKGYKVGTYTSPHILSFRERIRVDSQMIPEEDVV 102
Query: 501 QHFHRV 518
+HRV
Sbjct: 103 SLYHRV 108
>UniRef50_A6C8Q2 Cluster: Folyl-polyglutamate synthetase; n=1;
Planctomyces maris DSM 8797|Rep: Folyl-polyglutamate
synthetase - Planctomyces maris DSM 8797
Length = 477
Score = 69.7 bits (163), Expect = 4e-11
Identities = 31/57 (54%), Positives = 40/57 (70%)
Frame = +3
Query: 324 ELSVIHVAGTKGKGSTSAMCDSILRHHGFRTGFFSSPHLIAVRERIRLDGKIVSEEK 494
E+ IH+AGTKGKGSTSAM +L GFRTG F+SPH+ ERI +DG+ + E+
Sbjct: 52 EVRTIHIAGTKGKGSTSAMIAEMLSAAGFRTGLFTSPHITCYEERILIDGRQIEPEQ 108
>UniRef50_Q8G4M5 Cluster: Folylpolyglutamate synthase; n=4;
Bifidobacterium|Rep: Folylpolyglutamate synthase -
Bifidobacterium longum
Length = 529
Score = 69.3 bits (162), Expect = 6e-11
Identities = 33/79 (41%), Positives = 49/79 (62%)
Frame = +3
Query: 261 TNLEDMERYLFRTGVTLTKLDELSVIHVAGTKGKGSTSAMCDSILRHHGFRTGFFSSPHL 440
TNL D++R + VIH+ GT GKGST+ M ++I R +G RTG ++SPHL
Sbjct: 18 TNL-DLDRMNLMLDILGHPEQSFRVIHITGTNGKGSTARMAEAICRAYGMRTGLYTSPHL 76
Query: 441 IAVRERIRLDGKIVSEEKF 497
+ ERI +DG+ +S++ F
Sbjct: 77 EKINERIAIDGQQLSDDDF 95
>UniRef50_A5FP87 Cluster: FolC bifunctional protein; n=3;
Dehalococcoides|Rep: FolC bifunctional protein -
Dehalococcoides sp. BAV1
Length = 438
Score = 69.3 bits (162), Expect = 6e-11
Identities = 28/55 (50%), Positives = 44/55 (80%)
Frame = +3
Query: 327 LSVIHVAGTKGKGSTSAMCDSILRHHGFRTGFFSSPHLIAVRERIRLDGKIVSEE 491
+ +H+AGTKGKGST+++ S++ G+RTG ++SPHL+ RERI LDGK++S++
Sbjct: 36 IPAVHLAGTKGKGSTASLIASVMSVAGYRTGLYTSPHLLDFRERICLDGKMISKD 90
>UniRef50_A5D456 Cluster: Folylpolyglutamate synthase; n=1;
Pelotomaculum thermopropionicum SI|Rep:
Folylpolyglutamate synthase - Pelotomaculum
thermopropionicum SI
Length = 430
Score = 69.3 bits (162), Expect = 6e-11
Identities = 30/60 (50%), Positives = 41/60 (68%)
Frame = +3
Query: 324 ELSVIHVAGTKGKGSTSAMCDSILRHHGFRTGFFSSPHLIAVRERIRLDGKIVSEEKFAQ 503
+L IH+ GT GKGST+ M IL+ G+RTG F+SPHL + ER R+DG +S E+ A+
Sbjct: 41 DLKAIHIGGTNGKGSTAVMLAGILQKAGYRTGAFTSPHLHSFTERYRIDGACISRERIAE 100
>UniRef50_A0LIV6 Cluster: FolC bifunctional protein; n=1;
Syntrophobacter fumaroxidans MPOB|Rep: FolC bifunctional
protein - Syntrophobacter fumaroxidans (strain DSM 10017
/ MPOB)
Length = 431
Score = 69.3 bits (162), Expect = 6e-11
Identities = 31/64 (48%), Positives = 42/64 (65%)
Frame = +3
Query: 327 LSVIHVAGTKGKGSTSAMCDSILRHHGFRTGFFSSPHLIAVRERIRLDGKIVSEEKFAQH 506
L IH+AGT GKGST+AM S+LR HG R G ++SPHL+ ER R+D + V ++
Sbjct: 45 LRCIHIAGTNGKGSTAAMLSSMLRKHGVRVGLYTSPHLVRFTERFRIDEREVRIDRILAI 104
Query: 507 FHRV 518
F +V
Sbjct: 105 FEKV 108
>UniRef50_Q1PZI3 Cluster: Similar to multifunctional
folylpolyglutamate synthase/dihydrofolate synthase; n=1;
Candidatus Kuenenia stuttgartiensis|Rep: Similar to
multifunctional folylpolyglutamate
synthase/dihydrofolate synthase - Candidatus Kuenenia
stuttgartiensis
Length = 464
Score = 68.5 bits (160), Expect = 1e-10
Identities = 34/78 (43%), Positives = 50/78 (64%)
Frame = +3
Query: 264 NLEDMERYLFRTGVTLTKLDELSVIHVAGTKGKGSTSAMCDSILRHHGFRTGFFSSPHLI 443
NL+ M R L + G E S +H+ GTKGKGST+ M ++L+ G++TG F+SPHL
Sbjct: 43 NLDRMVRLLEQVG---NPHREFSSLHITGTKGKGSTAIMLSTVLQRAGYKTGLFTSPHLT 99
Query: 444 AVRERIRLDGKIVSEEKF 497
++ERI+L+ + EE F
Sbjct: 100 NLKERIQLNHTKIPEEDF 117
>UniRef50_Q1EVW0 Cluster: Folylpolyglutamate synthetase; n=1;
Clostridium oremlandii OhILAs|Rep: Folylpolyglutamate
synthetase - Clostridium oremlandii OhILAs
Length = 439
Score = 68.5 bits (160), Expect = 1e-10
Identities = 29/62 (46%), Positives = 45/62 (72%)
Frame = +3
Query: 321 DELSVIHVAGTKGKGSTSAMCDSILRHHGFRTGFFSSPHLIAVRERIRLDGKIVSEEKFA 500
++L IH+AGT GKGSTS+ S+L+ G++ G F+SPHL +RIR++G +S+E FA
Sbjct: 37 NQLKFIHIAGTNGKGSTSSFIHSMLKAEGYQVGLFTSPHLHCYTDRIRINGVNISKEDFA 96
Query: 501 QH 506
++
Sbjct: 97 RY 98
>UniRef50_A4VSD9 Cluster: Folylpolyglutamate synthase; n=2;
Streptococcus suis|Rep: Folylpolyglutamate synthase -
Streptococcus suis (strain 05ZYH33)
Length = 408
Score = 68.5 bits (160), Expect = 1e-10
Identities = 29/64 (45%), Positives = 42/64 (65%)
Frame = +3
Query: 333 VIHVAGTKGKGSTSAMCDSILRHHGFRTGFFSSPHLIAVRERIRLDGKIVSEEKFAQHFH 512
VIHVAGT GKGST A + + HG R G F SPH+++V +RI +D + +S+ F +
Sbjct: 39 VIHVAGTNGKGSTIAFMRKLFQAHGMRVGSFVSPHMVSVHDRICIDSQPISDHDFQHYLQ 98
Query: 513 RVYN 524
+VY+
Sbjct: 99 KVYD 102
>UniRef50_UPI000023EDF3 Cluster: hypothetical protein FG00685.1;
n=1; Gibberella zeae PH-1|Rep: hypothetical protein
FG00685.1 - Gibberella zeae PH-1
Length = 364
Score = 68.1 bits (159), Expect = 1e-10
Identities = 35/85 (41%), Positives = 50/85 (58%)
Frame = +3
Query: 267 LEDMERYLFRTGVTLTKLDELSVIHVAGTKGKGSTSAMCDSILRHHGFRTGFFSSPHLIA 446
+ +M +L R G L L IH+AGTKGKGS SA +LR + G ++SPHL++
Sbjct: 55 IPEMREWLRRAGYEPKDLARLKHIHIAGTKGKGSVSAFATGMLRQYE-TVGTYTSPHLVS 113
Query: 447 VRERIRLDGKIVSEEKFAQHFHRVY 521
RERI + G+ VS+ FA F ++
Sbjct: 114 PRERIAIQGEQVSQALFADAFFELW 138
>UniRef50_Q6A9I9 Cluster: Folylpolyglutamate synthase; n=1;
Propionibacterium acnes|Rep: Folylpolyglutamate synthase
- Propionibacterium acnes
Length = 481
Score = 68.1 bits (159), Expect = 1e-10
Identities = 32/62 (51%), Positives = 43/62 (69%)
Frame = +3
Query: 333 VIHVAGTKGKGSTSAMCDSILRHHGFRTGFFSSPHLIAVRERIRLDGKIVSEEKFAQHFH 512
VI +AGT GKGST+ M DS+LR G R G + SPHL+ V ERI +DG+ VS + F + +
Sbjct: 43 VIQIAGTNGKGSTAIMVDSLLRSAGLRVGRYCSPHLVDVTERICIDGRPVSHDLFDETWR 102
Query: 513 RV 518
+V
Sbjct: 103 QV 104
>UniRef50_Q9FN53 Cluster: Folylpolyglutamate synthase-like protein;
n=1; Arabidopsis thaliana|Rep: Folylpolyglutamate
synthase-like protein - Arabidopsis thaliana (Mouse-ear
cress)
Length = 480
Score = 68.1 bits (159), Expect = 1e-10
Identities = 31/62 (50%), Positives = 43/62 (69%)
Frame = +3
Query: 333 VIHVAGTKGKGSTSAMCDSILRHHGFRTGFFSSPHLIAVRERIRLDGKIVSEEKFAQHFH 512
V+HVAGTKGKGSTSA +ILR G+ G +SSPH+++++ERI +G+ VS F+
Sbjct: 77 VVHVAGTKGKGSTSAFLSNILRAGGYSVGCYSSPHILSIKERISCNGEPVSASTLNDLFY 136
Query: 513 RV 518
V
Sbjct: 137 SV 138
>UniRef50_Q8W041 Cluster: Dihydrofolate synthetase; n=5; core
eudicotyledons|Rep: Dihydrofolate synthetase -
Arabidopsis thaliana (Mouse-ear cress)
Length = 530
Score = 68.1 bits (159), Expect = 1e-10
Identities = 31/62 (50%), Positives = 43/62 (69%)
Frame = +3
Query: 333 VIHVAGTKGKGSTSAMCDSILRHHGFRTGFFSSPHLIAVRERIRLDGKIVSEEKFAQHFH 512
V+HVAGTKGKGSTSA +ILR G+ G +SSPH+++++ERI +G+ VS F+
Sbjct: 96 VVHVAGTKGKGSTSAFLSNILRAGGYSVGCYSSPHILSIKERISCNGEPVSASTLNDLFY 155
Query: 513 RV 518
V
Sbjct: 156 SV 157
>UniRef50_O67833 Cluster: Folylpolyglutamate synthetase; n=1;
Aquifex aeolicus|Rep: Folylpolyglutamate synthetase -
Aquifex aeolicus
Length = 410
Score = 67.7 bits (158), Expect = 2e-10
Identities = 31/52 (59%), Positives = 38/52 (73%)
Frame = +3
Query: 336 IHVAGTKGKGSTSAMCDSILRHHGFRTGFFSSPHLIAVRERIRLDGKIVSEE 491
I V GT GKGST A + ILR HGF+TG+F SPHLI+ ER R++GK + EE
Sbjct: 39 ILVGGTNGKGSTCAFTERILREHGFKTGWFVSPHLISENERWRINGKPIQEE 90
>UniRef50_Q03Y79 Cluster: Folylpolyglutamate synthase; n=1;
Leuconostoc mesenteroides subsp. mesenteroides ATCC
8293|Rep: Folylpolyglutamate synthase - Leuconostoc
mesenteroides subsp. mesenteroides (strain ATCC 8293
/NCDO 523)
Length = 441
Score = 67.7 bits (158), Expect = 2e-10
Identities = 28/64 (43%), Positives = 47/64 (73%)
Frame = +3
Query: 327 LSVIHVAGTKGKGSTSAMCDSILRHHGFRTGFFSSPHLIAVRERIRLDGKIVSEEKFAQH 506
L +IH+AGT GKGST M SIL+ +G+ G FSSP ++ RE+IR++G+++S+ F ++
Sbjct: 52 LKIIHIAGTNGKGSTGTMLGSILKANGYTYGHFSSPSIMDDREQIRINGEMISKSDFLKY 111
Query: 507 FHRV 518
+ ++
Sbjct: 112 YDQL 115
>UniRef50_A6LA17 Cluster: Folylpolyglutamate synthase; n=2;
Parabacteroides|Rep: Folylpolyglutamate synthase -
Parabacteroides distasonis (strain ATCC 8503 / DSM 20701
/ NCTC11152)
Length = 439
Score = 67.7 bits (158), Expect = 2e-10
Identities = 29/52 (55%), Positives = 40/52 (76%)
Frame = +3
Query: 336 IHVAGTKGKGSTSAMCDSILRHHGFRTGFFSSPHLIAVRERIRLDGKIVSEE 491
IHVAGT GKGS S + +ILR GF+ G ++SPHL+ RERIR++GK +S++
Sbjct: 49 IHVAGTNGKGSVSHLLAAILRQSGFKVGLYTSPHLVDFRERIRVNGKKISQD 100
>UniRef50_Q7SFD9 Cluster: Putative uncharacterized protein
NCU00893.1; n=1; Neurospora crassa|Rep: Putative
uncharacterized protein NCU00893.1 - Neurospora crassa
Length = 513
Score = 67.7 bits (158), Expect = 2e-10
Identities = 54/160 (33%), Positives = 81/160 (50%), Gaps = 34/160 (21%)
Frame = +3
Query: 147 MYSVKSNYEDAVHKLNKLQSNKSTI-----DQIRKDLRTGKRCTN-------LEDMERYL 290
M S + Y+DA+ +L +LQSN++ + D D ++ K + +M +L
Sbjct: 1 MASSQRTYDDALSRLAQLQSNRTIVNLFGSDDSNNDSQSKKPAAKKDLNSLAIPEMLSWL 60
Query: 291 FRTGVTLTKLDE--LSVIHVAGTKGKGSTSAMCDSILRHH----GFR------------- 413
R G T + L L +HVAGTKGKGS SA+ SI+ + F
Sbjct: 61 ARAGYTPSSLAATGLKCVHVAGTKGKGSVSALVSSIISQYPPPPSFHDDGGGGGAHIIQK 120
Query: 414 ---TGFFSSPHLIAVRERIRLDGKIVSEEKFAQHFHRVYN 524
G ++SPH+++VRERI+LD VS EKFA +F V++
Sbjct: 121 PVVVGTYTSPHVLSVRERIQLDNVPVSREKFALYFFEVWD 160
>UniRef50_A2QK88 Cluster: Contig An04c0360, complete genome; n=2;
Pezizomycotina|Rep: Contig An04c0360, complete genome -
Aspergillus niger
Length = 538
Score = 67.7 bits (158), Expect = 2e-10
Identities = 47/137 (34%), Positives = 75/137 (54%), Gaps = 14/137 (10%)
Frame = +3
Query: 153 SVKSNYEDAVHKLNKLQSNKSTIDQIRKDLRTGKRCTNLEDMERYLFRTGVTLTKLDELS 332
+V++ Y D + KLN L +N + Q++ + T + ++DM R+ G D L+
Sbjct: 30 NVETTYNDTLRKLNTLNTNFA-YRQLQ--IETVDQNVFIQDMLRWCRAVGYKSPDFDPLN 86
Query: 333 VIHVAGTKGKGSTSAMCDSIL-RHHGF-----RTGFFSSPHLIAVRERIRLDGK------ 476
+H+AG+KGKGSTSA +IL + G + G ++SPHL VRERIR+
Sbjct: 87 AVHIAGSKGKGSTSAFIFAILSEYQGHENPIKKLGLYTSPHLRTVRERIRISPSNDTPFH 146
Query: 477 --IVSEEKFAQHFHRVY 521
+SE++F Q+F V+
Sbjct: 147 HTSLSEDQFVQYFCDVW 163
>UniRef50_A1K4B2 Cluster: Dihydrofolate synthase /
Tetrahydrofolylpolyglutamate synthase; n=5;
Betaproteobacteria|Rep: Dihydrofolate synthase /
Tetrahydrofolylpolyglutamate synthase - Azoarcus sp.
(strain BH72)
Length = 432
Score = 67.3 bits (157), Expect = 2e-10
Identities = 31/65 (47%), Positives = 42/65 (64%)
Frame = +3
Query: 324 ELSVIHVAGTKGKGSTSAMCDSILRHHGFRTGFFSSPHLIAVRERIRLDGKIVSEEKFAQ 503
E VI V GT GKGST AM ++ILR G+R G ++SPHL+ ER+R+DG+ V + +
Sbjct: 41 ETVVITVGGTNGKGSTCAMLEAILRAEGYRVGCYTSPHLLRYNERVRVDGQDVDDARLVA 100
Query: 504 HFHRV 518
F V
Sbjct: 101 GFEAV 105
>UniRef50_Q62AJ8 Cluster: FolC bifunctional protein; n=25;
Betaproteobacteria|Rep: FolC bifunctional protein -
Burkholderia mallei (Pseudomonas mallei)
Length = 437
Score = 66.9 bits (156), Expect = 3e-10
Identities = 31/62 (50%), Positives = 40/62 (64%)
Frame = +3
Query: 333 VIHVAGTKGKGSTSAMCDSILRHHGFRTGFFSSPHLIAVRERIRLDGKIVSEEKFAQHFH 512
VI V GT GKGST A ++IL G++ G +SPHL+ ER RLDG+IV +E+ HF
Sbjct: 44 VITVGGTNGKGSTCAFIETILVRAGYKVGCHTSPHLLRFNERARLDGRIVDDEELLPHFE 103
Query: 513 RV 518
V
Sbjct: 104 AV 105
>UniRef50_Q31PP5 Cluster: FolC bifunctional protein; n=2;
Synechococcus elongatus|Rep: FolC bifunctional protein -
Synechococcus sp. (strain PCC 7942) (Anacystis nidulans
R2)
Length = 412
Score = 66.9 bits (156), Expect = 3e-10
Identities = 27/61 (44%), Positives = 46/61 (75%)
Frame = +3
Query: 321 DELSVIHVAGTKGKGSTSAMCDSILRHHGFRTGFFSSPHLIAVRERIRLDGKIVSEEKFA 500
+++ ++H+AGT GKGST A D+ LR +G+R G ++SPHLI+ ER++L+G+ VS ++
Sbjct: 37 NQIPIVHIAGTNGKGSTCAFVDTALRANGYRVGRYTSPHLISWCERLQLNGQQVSSDRLL 96
Query: 501 Q 503
+
Sbjct: 97 E 97
>UniRef50_A7CTY2 Cluster: FolC bifunctional protein; n=1;
Opitutaceae bacterium TAV2|Rep: FolC bifunctional
protein - Opitutaceae bacterium TAV2
Length = 448
Score = 66.9 bits (156), Expect = 3e-10
Identities = 30/60 (50%), Positives = 44/60 (73%)
Frame = +3
Query: 327 LSVIHVAGTKGKGSTSAMCDSILRHHGFRTGFFSSPHLIAVRERIRLDGKIVSEEKFAQH 506
+ VIHVAGT GKGS +AM +SILR G RTG ++SPHLI + ER+++D ++E + ++
Sbjct: 45 MPVIHVAGTNGKGSVAAMIESILRAAGLRTGLYTSPHLIRLGERVQVDRVPLTEAEIVRY 104
>UniRef50_A5ZW55 Cluster: Putative uncharacterized protein; n=1;
Ruminococcus obeum ATCC 29174|Rep: Putative
uncharacterized protein - Ruminococcus obeum ATCC 29174
Length = 433
Score = 66.9 bits (156), Expect = 3e-10
Identities = 27/65 (41%), Positives = 41/65 (63%)
Frame = +3
Query: 324 ELSVIHVAGTKGKGSTSAMCDSILRHHGFRTGFFSSPHLIAVRERIRLDGKIVSEEKFAQ 503
+ V+HVAGT GKGST A S+ R G+ G F+SPHL+ + ER +++ K + + F +
Sbjct: 38 QFQVVHVAGTNGKGSTCAFLTSVFREAGYSCGLFTSPHLVVINERFQINEKNIDNDTFLR 97
Query: 504 HFHRV 518
F +V
Sbjct: 98 AFEKV 102
>UniRef50_A5VL10 Cluster: FolC bifunctional protein; n=2;
Lactobacillus reuteri|Rep: FolC bifunctional protein -
Lactobacillus reuteri F275
Length = 419
Score = 66.9 bits (156), Expect = 3e-10
Identities = 31/83 (37%), Positives = 53/83 (63%), Gaps = 1/83 (1%)
Frame = +3
Query: 273 DMERYLFRTGVTLTKLDE-LSVIHVAGTKGKGSTSAMCDSILRHHGFRTGFFSSPHLIAV 449
D ++L R L D+ +IH+AGT GKGST M + L++ G+R G+FSSP L+
Sbjct: 21 DRVKFLRRILTRLGNPDQRFKIIHIAGTNGKGSTGTMLEQGLQNAGYRVGYFSSPALVDD 80
Query: 450 RERIRLDGKIVSEEKFAQHFHRV 518
RE+I+++ ++S++ FA + ++
Sbjct: 81 REQIKVNDHLISKKDFAMTYQKI 103
>UniRef50_Q38WN1 Cluster: Folylpolyglutamate synthase; n=1;
Lactobacillus sakei subsp. sakei 23K|Rep:
Folylpolyglutamate synthase - Lactobacillus sakei subsp.
sakei (strain 23K)
Length = 435
Score = 66.5 bits (155), Expect = 4e-10
Identities = 28/56 (50%), Positives = 43/56 (76%)
Frame = +3
Query: 330 SVIHVAGTKGKGSTSAMCDSILRHHGFRTGFFSSPHLIAVRERIRLDGKIVSEEKF 497
S+IHV GT GKGSTSAM +IL+ G+ G F+SPH++AV E I+++ +++S+ +F
Sbjct: 39 SIIHVCGTNGKGSTSAMIAAILQASGYSVGLFTSPHIMAVEESIQINRQLISKAQF 94
>UniRef50_A5WDG9 Cluster: FolC bifunctional protein; n=3;
Psychrobacter|Rep: FolC bifunctional protein -
Psychrobacter sp. PRwf-1
Length = 451
Score = 66.5 bits (155), Expect = 4e-10
Identities = 29/75 (38%), Positives = 47/75 (62%)
Frame = +3
Query: 294 RTGVTLTKLDELSVIHVAGTKGKGSTSAMCDSILRHHGFRTGFFSSPHLIAVRERIRLDG 473
R G+ + ++ V VAGT GKGST+A+ ++ + G++T + SPHLI ER+R+DG
Sbjct: 45 RLGLVKSAKEDAYVFMVAGTNGKGSTTAVISAVCQQAGYKTALYQSPHLIDFNERVRIDG 104
Query: 474 KIVSEEKFAQHFHRV 518
K V ++ F++V
Sbjct: 105 KPVGDQVLIDAFYQV 119
>UniRef50_A5KJF0 Cluster: Putative uncharacterized protein; n=2;
Clostridiales|Rep: Putative uncharacterized protein -
Ruminococcus torques ATCC 27756
Length = 445
Score = 66.5 bits (155), Expect = 4e-10
Identities = 29/66 (43%), Positives = 45/66 (68%)
Frame = +3
Query: 321 DELSVIHVAGTKGKGSTSAMCDSILRHHGFRTGFFSSPHLIAVRERIRLDGKIVSEEKFA 500
D+L IH+AGT GKGS A +IL G+R G + SP +++ RERI++DG+++S+ FA
Sbjct: 47 DDLRFIHIAGTNGKGSVLAYTSTILSEAGYRIGRYVSPTVVSYRERIQVDGEMISKHAFA 106
Query: 501 QHFHRV 518
+ +V
Sbjct: 107 EETEKV 112
>UniRef50_A5CR24 Cluster: FolC protein; n=4; Actinobacteria
(class)|Rep: FolC protein - Clavibacter michiganensis
subsp. michiganensis (strain NCPPB 382)
Length = 524
Score = 66.5 bits (155), Expect = 4e-10
Identities = 29/59 (49%), Positives = 42/59 (71%)
Frame = +3
Query: 333 VIHVAGTKGKGSTSAMCDSILRHHGFRTGFFSSPHLIAVRERIRLDGKIVSEEKFAQHF 509
++HV GT GK STS M +SILR G RTG F+SPHL+ ERI +DG +++E ++++
Sbjct: 121 IVHVTGTNGKTSTSRMTESILRAAGLRTGLFTSPHLVRFNERIVVDGLPITDEALSRNW 179
>UniRef50_Q38AL2 Cluster: Folylpolyglutamate-dihydrofolate
synthetase, putative; n=1; Trypanosoma brucei|Rep:
Folylpolyglutamate-dihydrofolate synthetase, putative -
Trypanosoma brucei
Length = 500
Score = 66.5 bits (155), Expect = 4e-10
Identities = 28/67 (41%), Positives = 46/67 (68%)
Frame = +3
Query: 318 LDELSVIHVAGTKGKGSTSAMCDSILRHHGFRTGFFSSPHLIAVRERIRLDGKIVSEEKF 497
LD L +HVAGTKGKG+T++ ++L +G + G F+SPH+ VRERI ++ +++ + F
Sbjct: 76 LDTLRFVHVAGTKGKGTTASYTAALLEAYGLKVGLFTSPHVKDVRERIMVNNEVLPMDTF 135
Query: 498 AQHFHRV 518
+F +V
Sbjct: 136 VHYFFQV 142
>UniRef50_Q04E69 Cluster: Folylpolyglutamate synthase; n=2;
Oenococcus oeni|Rep: Folylpolyglutamate synthase -
Oenococcus oeni (strain BAA-331 / PSU-1)
Length = 404
Score = 66.1 bits (154), Expect = 5e-10
Identities = 37/110 (33%), Positives = 58/110 (52%), Gaps = 2/110 (1%)
Frame = +3
Query: 198 LQSNKSTIDQIRKDLRTGKRCTN--LEDMERYLFRTGVTLTKLDELSVIHVAGTKGKGST 371
+++ ++ I + GKR + E + L + G KL ++IHV GT GKGS
Sbjct: 2 IENENEAVEWIHSLTKAGKRAKHDTQERLLNLLEKIGHPEKKLP--AIIHVTGTNGKGSV 59
Query: 372 SAMCDSILRHHGFRTGFFSSPHLIAVRERIRLDGKIVSEEKFAQHFHRVY 521
S +IL G+RTG F SP +I ERI +DGK +S++ ++ V+
Sbjct: 60 SRFSQAILTASGYRTGLFVSPFIIKFNERIEIDGKYISDDDLLKYTRIVF 109
>UniRef50_Q7UQM1 Cluster: Folylpolyglutamate synthase/dihydrofolate
synthase; n=1; Pirellula sp.|Rep: Folylpolyglutamate
synthase/dihydrofolate synthase - Rhodopirellula baltica
Length = 543
Score = 65.7 bits (153), Expect = 7e-10
Identities = 26/61 (42%), Positives = 43/61 (70%)
Frame = +3
Query: 312 TKLDELSVIHVAGTKGKGSTSAMCDSILRHHGFRTGFFSSPHLIAVRERIRLDGKIVSEE 491
+K + ++H+AGTKGKGS + M ++L G+R G ++SPHL+ + ER R+DG+I + E
Sbjct: 115 SKSTGVQIVHLAGTKGKGSAATMVAALLHSAGYRVGLYTSPHLVNLEERFRVDGEIATPE 174
Query: 492 K 494
+
Sbjct: 175 E 175
>UniRef50_Q3A6L0 Cluster: Folylpolyglutamate synthetase;
dihydrofolate synthetase; n=1; Pelobacter carbinolicus
DSM 2380|Rep: Folylpolyglutamate synthetase;
dihydrofolate synthetase - Pelobacter carbinolicus
(strain DSM 2380 / Gra Bd 1)
Length = 422
Score = 65.7 bits (153), Expect = 7e-10
Identities = 37/83 (44%), Positives = 52/83 (62%), Gaps = 9/83 (10%)
Frame = +3
Query: 267 LEDMERYLFRTGVT-----LTKLDE----LSVIHVAGTKGKGSTSAMCDSILRHHGFRTG 419
L ++R+ + G+T L +LD + ++HVAGT GKGS SA IL+ G+RTG
Sbjct: 10 LYGLQRFGIKLGLTNIQTLLARLDHPERAMRIVHVAGTNGKGSVSAATALILQTAGYRTG 69
Query: 420 FFSSPHLIAVRERIRLDGKIVSE 488
++SPHL + ERIR+DG VSE
Sbjct: 70 LYTSPHLHSFTERIRIDGVQVSE 92
>UniRef50_Q12D50 Cluster: FolC bifunctional protein; n=1;
Polaromonas sp. JS666|Rep: FolC bifunctional protein -
Polaromonas sp. (strain JS666 / ATCC BAA-500)
Length = 501
Score = 65.7 bits (153), Expect = 7e-10
Identities = 32/62 (51%), Positives = 41/62 (66%)
Frame = +3
Query: 333 VIHVAGTKGKGSTSAMCDSILRHHGFRTGFFSSPHLIAVRERIRLDGKIVSEEKFAQHFH 512
VI VAGT GKGST AM ++IL G+RTG ++SPHL+ ER R+ G IV+ +F
Sbjct: 53 VITVAGTNGKGSTCAMLEAILLEAGYRTGVYTSPHLVHFEERCRVRGDIVNATDLVANFA 112
Query: 513 RV 518
RV
Sbjct: 113 RV 114
>UniRef50_A5ZI35 Cluster: Putative uncharacterized protein; n=1;
Bacteroides caccae ATCC 43185|Rep: Putative
uncharacterized protein - Bacteroides caccae ATCC 43185
Length = 493
Score = 65.7 bits (153), Expect = 7e-10
Identities = 27/56 (48%), Positives = 40/56 (71%)
Frame = +3
Query: 324 ELSVIHVAGTKGKGSTSAMCDSILRHHGFRTGFFSSPHLIAVRERIRLDGKIVSEE 491
+ IH+AGT GKGS S ++L+ G+R G F+SPHL+ RERIR++G+++ EE
Sbjct: 45 QFKTIHIAGTNGKGSCSHTIAAVLQSAGYRVGLFTSPHLVDFRERIRINGEMIPEE 100
>UniRef50_A5FMS8 Cluster: FolC bifunctional protein; n=14;
Bacteroidetes|Rep: FolC bifunctional protein -
Flavobacterium johnsoniae UW101
Length = 408
Score = 65.7 bits (153), Expect = 7e-10
Identities = 28/56 (50%), Positives = 42/56 (75%)
Frame = +3
Query: 324 ELSVIHVAGTKGKGSTSAMCDSILRHHGFRTGFFSSPHLIAVRERIRLDGKIVSEE 491
+L IHVAGT GKGSTS M S+L+ G++ G ++SPHL RERI+++G+ ++E+
Sbjct: 45 KLQTIHVAGTNGKGSTSHMLASVLQEAGYKVGLYTSPHLKDFRERIKINGQEITED 100
>UniRef50_Q727H3 Cluster: Folylpolyglutamate synthase; n=2;
Desulfovibrio vulgaris subsp. vulgaris|Rep:
Folylpolyglutamate synthase - Desulfovibrio vulgaris
(strain Hildenborough / ATCC 29579 / NCIMB8303)
Length = 498
Score = 65.3 bits (152), Expect = 1e-09
Identities = 28/56 (50%), Positives = 39/56 (69%)
Frame = +3
Query: 330 SVIHVAGTKGKGSTSAMCDSILRHHGFRTGFFSSPHLIAVRERIRLDGKIVSEEKF 497
+V V GT GKGSTS SI + HG RTG ++SPH I RERIR+DG+++ +++
Sbjct: 43 AVAQVVGTNGKGSTSTFLASIAQAHGLRTGLYTSPHFITPRERIRIDGRMLEADQW 98
>UniRef50_Q0LMK1 Cluster: FolC bifunctional protein; n=1;
Herpetosiphon aurantiacus ATCC 23779|Rep: FolC
bifunctional protein - Herpetosiphon aurantiacus ATCC
23779
Length = 435
Score = 65.3 bits (152), Expect = 1e-09
Identities = 28/59 (47%), Positives = 43/59 (72%)
Frame = +3
Query: 342 VAGTKGKGSTSAMCDSILRHHGFRTGFFSSPHLIAVRERIRLDGKIVSEEKFAQHFHRV 518
VAGTKGKGST A +SI+R G + GFFSSPHL + RER++++ +++S+ + ++V
Sbjct: 53 VAGTKGKGSTCAFLESIIRQSGLKVGFFSSPHLHSYRERMQINRELISQSQLVDLINQV 111
>UniRef50_A7LS10 Cluster: Putative uncharacterized protein; n=1;
Bacteroides ovatus ATCC 8483|Rep: Putative
uncharacterized protein - Bacteroides ovatus ATCC 8483
Length = 496
Score = 65.3 bits (152), Expect = 1e-09
Identities = 28/56 (50%), Positives = 40/56 (71%)
Frame = +3
Query: 324 ELSVIHVAGTKGKGSTSAMCDSILRHHGFRTGFFSSPHLIAVRERIRLDGKIVSEE 491
+ IH+AGT GKGS S ++L+ G+R G F+SPHLI RERIR++G+++ EE
Sbjct: 45 QFKTIHIAGTNGKGSCSHTIAAVLQCAGYRVGLFTSPHLIDFRERIRINGEMIPEE 100
>UniRef50_A1SMD5 Cluster: FolC bifunctional protein; n=5;
Actinomycetales|Rep: FolC bifunctional protein -
Nocardioides sp. (strain BAA-499 / JS614)
Length = 460
Score = 65.3 bits (152), Expect = 1e-09
Identities = 31/62 (50%), Positives = 44/62 (70%)
Frame = +3
Query: 333 VIHVAGTKGKGSTSAMCDSILRHHGFRTGFFSSPHLIAVRERIRLDGKIVSEEKFAQHFH 512
VIH+ GT GK STS M D++LR RTG F+SPH+ + ERI +DG+ +S+E+F + F+
Sbjct: 53 VIHLTGTNGKTSTSRMIDTLLRALDLRTGRFTSPHVERMTERISVDGEPLSDEEFVRAFN 112
Query: 513 RV 518
V
Sbjct: 113 DV 114
>UniRef50_A0UYZ7 Cluster: FolC bifunctional protein; n=1;
Clostridium cellulolyticum H10|Rep: FolC bifunctional
protein - Clostridium cellulolyticum H10
Length = 424
Score = 65.3 bits (152), Expect = 1e-09
Identities = 29/67 (43%), Positives = 44/67 (65%)
Frame = +3
Query: 324 ELSVIHVAGTKGKGSTSAMCDSILRHHGFRTGFFSSPHLIAVRERIRLDGKIVSEEKFAQ 503
+L IH+AGT GKGST+A SIL G+RTG F+SP++ ERI++D +S ++ A+
Sbjct: 38 KLKFIHIAGTNGKGSTTAFISSILIEAGYRTGMFTSPYIQRFTERIKVDNNEISNDELAE 97
Query: 504 HFHRVYN 524
++ N
Sbjct: 98 LISQIKN 104
>UniRef50_Q1FIY8 Cluster: FolC bifunctional protein; n=1;
Clostridium phytofermentans ISDg|Rep: FolC bifunctional
protein - Clostridium phytofermentans ISDg
Length = 424
Score = 64.9 bits (151), Expect = 1e-09
Identities = 30/60 (50%), Positives = 41/60 (68%)
Frame = +3
Query: 324 ELSVIHVAGTKGKGSTSAMCDSILRHHGFRTGFFSSPHLIAVRERIRLDGKIVSEEKFAQ 503
+L IHVAGT GKGST M SILR G + G F+SP L E+I+++G+++S E FA+
Sbjct: 38 KLKFIHVAGTNGKGSTCKMLSSILRCAGLKVGLFTSPFLETENEQIQINGEVISNEDFAK 97
>UniRef50_A3IEY2 Cluster: Folyl-polyglutamate synthetase; n=1;
Bacillus sp. B14905|Rep: Folyl-polyglutamate synthetase
- Bacillus sp. B14905
Length = 426
Score = 64.9 bits (151), Expect = 1e-09
Identities = 28/66 (42%), Positives = 47/66 (71%)
Frame = +3
Query: 321 DELSVIHVAGTKGKGSTSAMCDSILRHHGFRTGFFSSPHLIAVRERIRLDGKIVSEEKFA 500
++L VIHVAG+ GKGST +L+H G + G F+SPHL V ER+ ++G+ +++E+F
Sbjct: 36 NKLRVIHVAGSNGKGSTVNALREMLQHTGHQVGAFTSPHLERVNERMTINGEPITDEQFL 95
Query: 501 QHFHRV 518
+F+++
Sbjct: 96 YYFNKL 101
>UniRef50_Q3JCB5 Cluster: Folylpolyglutamate synthetase; n=1;
Nitrosococcus oceani ATCC 19707|Rep: Folylpolyglutamate
synthetase - Nitrosococcus oceani (strain ATCC 19707 /
NCIMB 11848)
Length = 432
Score = 64.5 bits (150), Expect = 2e-09
Identities = 27/62 (43%), Positives = 43/62 (69%)
Frame = +3
Query: 333 VIHVAGTKGKGSTSAMCDSILRHHGFRTGFFSSPHLIAVRERIRLDGKIVSEEKFAQHFH 512
++ +AGT GKGST A+ ++IL G+R G ++SPHL+ ERI++ G+ VS++ Q F
Sbjct: 45 IVTIAGTNGKGSTVALLEAILLAAGYRVGSYTSPHLLRYNERIKIQGEAVSDDIICQSFA 104
Query: 513 RV 518
R+
Sbjct: 105 RI 106
>UniRef50_A4RLF9 Cluster: Putative uncharacterized protein; n=1;
Magnaporthe grisea|Rep: Putative uncharacterized protein
- Magnaporthe grisea (Rice blast fungus) (Pyricularia
grisea)
Length = 987
Score = 64.5 bits (150), Expect = 2e-09
Identities = 31/66 (46%), Positives = 45/66 (68%), Gaps = 4/66 (6%)
Frame = +3
Query: 336 IHVAGTKGKGSTSAMCDSILRHH----GFRTGFFSSPHLIAVRERIRLDGKIVSEEKFAQ 503
IH+AGTKGKGS + SIL + G ++SPH+ VRERI++DG+++SEE+F +
Sbjct: 349 IHIAGTKGKGSVAHYITSILTSPVGLGAGKIGTYTSPHINTVRERIKIDGEMLSEEEFTK 408
Query: 504 HFHRVY 521
HF R +
Sbjct: 409 HFFRFW 414
>UniRef50_Q7MWW9 Cluster: Folylpolyglutamate synthase; n=2;
Bacteroidales|Rep: Folylpolyglutamate synthase -
Porphyromonas gingivalis (Bacteroides gingivalis)
Length = 429
Score = 64.1 bits (149), Expect = 2e-09
Identities = 29/52 (55%), Positives = 39/52 (75%)
Frame = +3
Query: 336 IHVAGTKGKGSTSAMCDSILRHHGFRTGFFSSPHLIAVRERIRLDGKIVSEE 491
IHVAGT GKGST++ +IL+ G R G F+SPHL+ RERIR++G ++EE
Sbjct: 50 IHVAGTNGKGSTASTLAAILQVAGMRVGLFTSPHLVDFRERIRVNGICITEE 101
>UniRef50_Q4P0W7 Cluster: Putative uncharacterized protein; n=1;
Ustilago maydis|Rep: Putative uncharacterized protein -
Ustilago maydis (Smut fungus)
Length = 1553
Score = 64.1 bits (149), Expect = 2e-09
Identities = 38/80 (47%), Positives = 50/80 (62%), Gaps = 1/80 (1%)
Frame = +3
Query: 267 LEDMERYLFRTGVTLTKLDELSVIHVAGTKGKGSTSAMCDSILRHH-GFRTGFFSSPHLI 443
LE + R L R G + + VIHVAGT GKG+T A DS+LR+ RTG F SPHLI
Sbjct: 1024 LERITRLLARLG---SPHKQFPVIHVAGTNGKGTTIAYLDSVLRNALDIRTGTFVSPHLI 1080
Query: 444 AVRERIRLDGKIVSEEKFAQ 503
R+ ++DGK+VS+ + Q
Sbjct: 1081 ERRDCCKVDGKMVSKSLWKQ 1100
>UniRef50_A7D4G5 Cluster: Dihydropteroate synthase; n=1; Halorubrum
lacusprofundi ATCC 49239|Rep: Dihydropteroate synthase -
Halorubrum lacusprofundi ATCC 49239
Length = 878
Score = 64.1 bits (149), Expect = 2e-09
Identities = 28/66 (42%), Positives = 43/66 (65%)
Frame = +3
Query: 321 DELSVIHVAGTKGKGSTSAMCDSILRHHGFRTGFFSSPHLIAVRERIRLDGKIVSEEKFA 500
+++S + VAG+ GKGST+ M +SILR G G ++SPHL A+ +R+R+DG ++E A
Sbjct: 37 EDVSFVQVAGSNGKGSTARMTESILREAGLSVGLYTSPHLSALADRVRVDGLAMTEAAIA 96
Query: 501 QHFHRV 518
V
Sbjct: 97 DFVEEV 102
>UniRef50_Q2LQC5 Cluster: Folylpolyglutamate synthase /
dihydrofolate synthase; n=1; Syntrophus aciditrophicus
SB|Rep: Folylpolyglutamate synthase / dihydrofolate
synthase - Syntrophus aciditrophicus (strain SB)
Length = 465
Score = 63.7 bits (148), Expect = 3e-09
Identities = 25/56 (44%), Positives = 40/56 (71%)
Frame = +3
Query: 342 VAGTKGKGSTSAMCDSILRHHGFRTGFFSSPHLIAVRERIRLDGKIVSEEKFAQHF 509
+ GT GKGST+A+ IL+ G++ G ++SPHL ++ ERIR++G ++SEE+ F
Sbjct: 75 IGGTNGKGSTAAILSCILKESGYKVGLYTSPHLTSICERIRINGSLISEERMQDCF 130
>UniRef50_A6TN35 Cluster: FolC bifunctional protein; n=2;
Clostridiaceae|Rep: FolC bifunctional protein -
Alkaliphilus metalliredigens QYMF
Length = 439
Score = 63.7 bits (148), Expect = 3e-09
Identities = 27/60 (45%), Positives = 42/60 (70%)
Frame = +3
Query: 324 ELSVIHVAGTKGKGSTSAMCDSILRHHGFRTGFFSSPHLIAVRERIRLDGKIVSEEKFAQ 503
++ VIHVAGT GKGS +++ S+L+ G+R G ++SP+L ERIR+ G+ + E+ AQ
Sbjct: 38 KVKVIHVAGTNGKGSIASLIHSVLKTQGYRVGLYTSPYLEEFTERIRISGEDIPRERLAQ 97
>UniRef50_A4M5Q3 Cluster: FolC bifunctional protein; n=1; Petrotoga
mobilis SJ95|Rep: FolC bifunctional protein - Petrotoga
mobilis SJ95
Length = 438
Score = 63.7 bits (148), Expect = 3e-09
Identities = 24/61 (39%), Positives = 43/61 (70%)
Frame = +3
Query: 336 IHVAGTKGKGSTSAMCDSILRHHGFRTGFFSSPHLIAVRERIRLDGKIVSEEKFAQHFHR 515
IH+ GT GKGS + ILR +G + G + SPHL+++ ERI+++G+ +SE++F + ++
Sbjct: 44 IHITGTNGKGSVTTAISRILRFNGMKVGTYISPHLVSITERIKVNGENISEKEFVEIYNE 103
Query: 516 V 518
+
Sbjct: 104 I 104
>UniRef50_A3ZWP1 Cluster: Folyl-polyglutamate synthetase; n=1;
Blastopirellula marina DSM 3645|Rep: Folyl-polyglutamate
synthetase - Blastopirellula marina DSM 3645
Length = 470
Score = 63.7 bits (148), Expect = 3e-09
Identities = 27/67 (40%), Positives = 42/67 (62%)
Frame = +3
Query: 318 LDELSVIHVAGTKGKGSTSAMCDSILRHHGFRTGFFSSPHLIAVRERIRLDGKIVSEEKF 497
+D+L ++H+AGTKGKGST+ +IL G++ G FSSPHL + ER ++ S ++
Sbjct: 64 VDQLKIVHIAGTKGKGSTATTLSAILEADGYQVGLFSSPHLERLEERFAINRIACSADEV 123
Query: 498 AQHFHRV 518
Q H +
Sbjct: 124 TQLIHDI 130
>UniRef50_Q6MAP9 Cluster: Putative folylpolyglutamate synthase; n=1;
Candidatus Protochlamydia amoebophila UWE25|Rep:
Putative folylpolyglutamate synthase - Protochlamydia
amoebophila (strain UWE25)
Length = 410
Score = 63.3 bits (147), Expect = 4e-09
Identities = 29/65 (44%), Positives = 43/65 (66%)
Frame = +3
Query: 330 SVIHVAGTKGKGSTSAMCDSILRHHGFRTGFFSSPHLIAVRERIRLDGKIVSEEKFAQHF 509
S IHVAGT GKGS A S L + G+R G ++SPH+ + RERIR++G ++SE +
Sbjct: 41 SSIHVAGTNGKGSVVAKIASALEYAGYRVGVYTSPHISSFRERIRVNGIMISEADVEKIL 100
Query: 510 HRVYN 524
+++N
Sbjct: 101 SQLFN 105
>UniRef50_Q8RBN3 Cluster: Folylpolyglutamate synthase; n=5;
Clostridia|Rep: Folylpolyglutamate synthase -
Thermoanaerobacter tengcongensis
Length = 431
Score = 62.9 bits (146), Expect = 5e-09
Identities = 34/99 (34%), Positives = 55/99 (55%)
Frame = +3
Query: 210 KSTIDQIRKDLRTGKRCTNLEDMERYLFRTGVTLTKLDELSVIHVAGTKGKGSTSAMCDS 389
+ I I + G + LE+++R L G L +IHVAGT GKGSTS+ S
Sbjct: 7 EEAIQYIHSTYKFGMKL-GLENIKRLLGYMG---NPEKNLKIIHVAGTNGKGSTSSFISS 62
Query: 390 ILRHHGFRTGFFSSPHLIAVRERIRLDGKIVSEEKFAQH 506
IL+ G++ ++SP+L ER++++G+ +S EK +
Sbjct: 63 ILKEAGYKVALYTSPYLEEFEERMKINGENISREKLVYY 101
>UniRef50_Q8A839 Cluster: Folylpolyglutamate synthase; n=1;
Bacteroides thetaiotaomicron|Rep: Folylpolyglutamate
synthase - Bacteroides thetaiotaomicron
Length = 491
Score = 62.9 bits (146), Expect = 5e-09
Identities = 26/56 (46%), Positives = 40/56 (71%)
Frame = +3
Query: 324 ELSVIHVAGTKGKGSTSAMCDSILRHHGFRTGFFSSPHLIAVRERIRLDGKIVSEE 491
+ IH+AGT GKGS S ++L+ G++ G F+SPHLI RERIR++G+++ E+
Sbjct: 45 QFRTIHIAGTNGKGSCSHTIAAVLQAAGYKVGLFTSPHLIDFRERIRINGEMIPED 100
>UniRef50_A6WDS1 Cluster: FolC bifunctional protein precursor; n=1;
Kineococcus radiotolerans SRS30216|Rep: FolC
bifunctional protein precursor - Kineococcus
radiotolerans SRS30216
Length = 526
Score = 62.9 bits (146), Expect = 5e-09
Identities = 26/57 (45%), Positives = 39/57 (68%)
Frame = +3
Query: 333 VIHVAGTKGKGSTSAMCDSILRHHGFRTGFFSSPHLIAVRERIRLDGKIVSEEKFAQ 503
V+H+AGT GK ST+ M + ++R H RTG F+SPHL+ + ERI +DG ++ F +
Sbjct: 117 VVHLAGTNGKTSTARMVERLVREHDLRTGRFTSPHLVDITERIAVDGDPITHAAFVR 173
>UniRef50_Q1IVH6 Cluster: FolC bifunctional protein; n=1;
Acidobacteria bacterium Ellin345|Rep: FolC bifunctional
protein - Acidobacteria bacterium (strain Ellin345)
Length = 447
Score = 62.5 bits (145), Expect = 7e-09
Identities = 26/59 (44%), Positives = 40/59 (67%)
Frame = +3
Query: 342 VAGTKGKGSTSAMCDSILRHHGFRTGFFSSPHLIAVRERIRLDGKIVSEEKFAQHFHRV 518
+AGT GKGST+A SIL G++TG ++SPHL+ + ER R++G V++ +F + V
Sbjct: 49 IAGTNGKGSTAATLSSILLAAGYKTGLYTSPHLVKINERFRINGSQVNDAEFTAAYEHV 107
>UniRef50_Q1D8V1 Cluster: Tetrahydrofolylpolyglutamate
synthase/dihydrofolate synthase; n=2;
Cystobacterineae|Rep: Tetrahydrofolylpolyglutamate
synthase/dihydrofolate synthase - Myxococcus xanthus
(strain DK 1622)
Length = 410
Score = 62.5 bits (145), Expect = 7e-09
Identities = 28/54 (51%), Positives = 37/54 (68%)
Frame = +3
Query: 336 IHVAGTKGKGSTSAMCDSILRHHGFRTGFFSSPHLIAVRERIRLDGKIVSEEKF 497
+HVAGT GKGST AM + L G R G ++SPHL+ V ERIR+D + +S+ F
Sbjct: 21 LHVAGTNGKGSTCAMTAASLHAAGHRVGLYTSPHLVRVNERIRVDSEDISDADF 74
>UniRef50_A3HTE9 Cluster: Folylpolyglutamate synthase; n=3;
Bacteria|Rep: Folylpolyglutamate synthase - Algoriphagus
sp. PR1
Length = 428
Score = 62.5 bits (145), Expect = 7e-09
Identities = 28/56 (50%), Positives = 40/56 (71%)
Frame = +3
Query: 336 IHVAGTKGKGSTSAMCDSILRHHGFRTGFFSSPHLIAVRERIRLDGKIVSEEKFAQ 503
IHVAGT GKGSTS +IL+ G++TG ++SPHL + ERI++DG + E++ Q
Sbjct: 49 IHVAGTNGKGSTSHSLAAILQKAGYKTGLYTSPHLKSFTERIKIDGIEIPEDEVVQ 104
>UniRef50_A0YB05 Cluster: FolC bifunctional protein; n=1; marine
gamma proteobacterium HTCC2143|Rep: FolC bifunctional
protein - marine gamma proteobacterium HTCC2143
Length = 428
Score = 62.5 bits (145), Expect = 7e-09
Identities = 30/67 (44%), Positives = 42/67 (62%)
Frame = +3
Query: 318 LDELSVIHVAGTKGKGSTSAMCDSILRHHGFRTGFFSSPHLIAVRERIRLDGKIVSEEKF 497
LD VI VAGT GKGST A+ +++LR G+ F+SPH + ERI+LD VS++
Sbjct: 39 LDRSKVITVAGTNGKGSTVAVLNTLLRSAGYSVACFTSPHFLRYNERIKLDDCDVSDQLL 98
Query: 498 AQHFHRV 518
+ F R+
Sbjct: 99 IESFDRI 105
>UniRef50_Q13EI5 Cluster: FolC bifunctional protein; n=3;
Rhodopseudomonas palustris|Rep: FolC bifunctional
protein - Rhodopseudomonas palustris (strain BisB5)
Length = 438
Score = 62.1 bits (144), Expect = 9e-09
Identities = 32/77 (41%), Positives = 44/77 (57%)
Frame = +3
Query: 288 LFRTGVTLTKLDELSVIHVAGTKGKGSTSAMCDSILRHHGFRTGFFSSPHLIAVRERIRL 467
L R GV +L ++V V G+ GKGST+A I R HG RTG F+SPHL ER ++
Sbjct: 20 LDRLGVDRARLQRIAVA-VCGSNGKGSTAAFTAGIGRAHGLRTGLFTSPHLYRFNERFQI 78
Query: 468 DGKIVSEEKFAQHFHRV 518
DG + ++ + RV
Sbjct: 79 DGAPIPDDALRRLLERV 95
>UniRef50_Q1QY39 Cluster: FolC bifunctional protein; n=1;
Chromohalobacter salexigens DSM 3043|Rep: FolC
bifunctional protein - Chromohalobacter salexigens
(strain DSM 3043 / ATCC BAA-138 / NCIMB13768)
Length = 437
Score = 62.1 bits (144), Expect = 9e-09
Identities = 29/62 (46%), Positives = 38/62 (61%)
Frame = +3
Query: 333 VIHVAGTKGKGSTSAMCDSILRHHGFRTGFFSSPHLIAVRERIRLDGKIVSEEKFAQHFH 512
VI VAGT GKGST AM +++ R HG RT ++SPHL+ ER+RL G + + F
Sbjct: 47 VITVAGTNGKGSTVAMLEAVAREHGLRTAAYTSPHLLRYNERLRLAGCEADDAALVEGFE 106
Query: 513 RV 518
V
Sbjct: 107 AV 108
>UniRef50_A1W9F5 Cluster: FolC bifunctional protein; n=33;
Burkholderiales|Rep: FolC bifunctional protein -
Acidovorax sp. (strain JS42)
Length = 441
Score = 62.1 bits (144), Expect = 9e-09
Identities = 29/62 (46%), Positives = 38/62 (61%)
Frame = +3
Query: 333 VIHVAGTKGKGSTSAMCDSILRHHGFRTGFFSSPHLIAVRERIRLDGKIVSEEKFAQHFH 512
VI VAGT GKGST AM +++ G+RTG ++SPHL+ ER R+ G+IV F
Sbjct: 45 VITVAGTNGKGSTCAMLEAVALQAGYRTGVYTSPHLVHFEERCRIRGEIVDAASLVASFE 104
Query: 513 RV 518
V
Sbjct: 105 AV 106
>UniRef50_Q8XJ43 Cluster: Folyl-polyglutamate synthetase; n=13;
Clostridium|Rep: Folyl-polyglutamate synthetase -
Clostridium perfringens
Length = 440
Score = 61.7 bits (143), Expect = 1e-08
Identities = 25/55 (45%), Positives = 40/55 (72%)
Frame = +3
Query: 336 IHVAGTKGKGSTSAMCDSILRHHGFRTGFFSSPHLIAVRERIRLDGKIVSEEKFA 500
IH+ GT GKGST+AM S+LR GF+ G ++SP+L ERI+++G+ ++++ A
Sbjct: 42 IHIGGTNGKGSTTAMISSVLREAGFKVGMYTSPYLEEFEERIQINGENINKDDLA 96
>UniRef50_Q2RNS0 Cluster: Folylpolyglutamate synthetase; n=4;
Rhodospirillaceae|Rep: Folylpolyglutamate synthetase -
Rhodospirillum rubrum (strain ATCC 11170 / NCIB 8255)
Length = 435
Score = 61.7 bits (143), Expect = 1e-08
Identities = 27/53 (50%), Positives = 37/53 (69%)
Frame = +3
Query: 333 VIHVAGTKGKGSTSAMCDSILRHHGFRTGFFSSPHLIAVRERIRLDGKIVSEE 491
VIHVAGT GKGS A C ++L G+R ++SPHL+ ERIRL G ++++E
Sbjct: 43 VIHVAGTNGKGSVVATCRALLEAAGYRVHVYTSPHLVRFGERIRLAGTLIADE 95
>UniRef50_O83360 Cluster: Folylpolyglutamate synthetase; n=1;
Treponema pallidum|Rep: Folylpolyglutamate synthetase -
Treponema pallidum
Length = 490
Score = 61.7 bits (143), Expect = 1e-08
Identities = 30/63 (47%), Positives = 40/63 (63%)
Frame = +3
Query: 336 IHVAGTKGKGSTSAMCDSILRHHGFRTGFFSSPHLIAVRERIRLDGKIVSEEKFAQHFHR 515
IHVAGTKGKGS++ M +IL GF TG ++SPH++ RERI G S ++A
Sbjct: 85 IHVAGTKGKGSSARMLAAILNEIGFNTGLYASPHVMDPRERITRAGVFFSPAEYASACTH 144
Query: 516 VYN 524
VY+
Sbjct: 145 VYH 147
>UniRef50_Q1MS38 Cluster: Folylpolyglutamate synthase; n=1; Lawsonia
intracellularis PHE/MN1-00|Rep: Folylpolyglutamate
synthase - Lawsonia intracellularis (strain PHE/MN1-00)
Length = 435
Score = 61.7 bits (143), Expect = 1e-08
Identities = 31/79 (39%), Positives = 48/79 (60%), Gaps = 4/79 (5%)
Frame = +3
Query: 267 LEDMERYLFRTGVTLTKLDELS----VIHVAGTKGKGSTSAMCDSILRHHGFRTGFFSSP 434
L +++ L R LTKLD S V+ + GT GKGST+ S+ + HG + G ++SP
Sbjct: 18 LFNIDLELTRMNQALTKLDFNSLPYKVVQIVGTNGKGSTATFLASLAKSHGLKVGIYTSP 77
Query: 435 HLIAVRERIRLDGKIVSEE 491
H + RERI ++G+++S E
Sbjct: 78 HFVTPRERICINGEMLSPE 96
>UniRef50_A5TUM3 Cluster: Tetrahydrofolate synthase; n=3;
Fusobacterium nucleatum|Rep: Tetrahydrofolate synthase -
Fusobacterium nucleatum subsp. polymorphum ATCC 10953
Length = 415
Score = 61.7 bits (143), Expect = 1e-08
Identities = 26/62 (41%), Positives = 40/62 (64%)
Frame = +3
Query: 333 VIHVAGTKGKGSTSAMCDSILRHHGFRTGFFSSPHLIAVRERIRLDGKIVSEEKFAQHFH 512
VIH+ GT GKGS S + IL G++ G ++SPH++ ERI + K +S+E A+++
Sbjct: 45 VIHITGTNGKGSVSTTVERILLDAGYKVGKYTSPHILKFNERIIFNDKYISDENVAKYYE 104
Query: 513 RV 518
RV
Sbjct: 105 RV 106
>UniRef50_Q2QLY6 Cluster: Dihydrofolate
synthetase/folylpolyglutamate synthetase, putative,
expressed; n=1; Oryza sativa (japonica
cultivar-group)|Rep: Dihydrofolate
synthetase/folylpolyglutamate synthetase, putative,
expressed - Oryza sativa subsp. japonica (Rice)
Length = 510
Score = 61.7 bits (143), Expect = 1e-08
Identities = 30/66 (45%), Positives = 41/66 (62%)
Frame = +3
Query: 264 NLEDMERYLFRTGVTLTKLDELSVIHVAGTKGKGSTSAMCDSILRHHGFRTGFFSSPHLI 443
+L M R L R G T +H+AGTKGKGST+A +I+R G+ G ++SPHL+
Sbjct: 25 DLGRMRRLLRRLGDPHT---HFPAVHIAGTKGKGSTAAFLSNIMREQGYNVGCYTSPHLL 81
Query: 444 AVRERI 461
+RERI
Sbjct: 82 TIRERI 87
>UniRef50_Q0ILT5 Cluster: Os12g0623800 protein; n=2; Oryza
sativa|Rep: Os12g0623800 protein - Oryza sativa subsp.
japonica (Rice)
Length = 390
Score = 61.7 bits (143), Expect = 1e-08
Identities = 30/66 (45%), Positives = 41/66 (62%)
Frame = +3
Query: 264 NLEDMERYLFRTGVTLTKLDELSVIHVAGTKGKGSTSAMCDSILRHHGFRTGFFSSPHLI 443
+L M R L R G T +H+AGTKGKGST+A +I+R G+ G ++SPHL+
Sbjct: 48 DLGRMRRLLRRLGDPHT---HFPAVHIAGTKGKGSTAAFLSNIMREQGYNVGCYTSPHLL 104
Query: 444 AVRERI 461
+RERI
Sbjct: 105 TIRERI 110
>UniRef50_Q64S09 Cluster: Folylpolyglutamate synthase; n=2;
Bacteroides fragilis|Rep: Folylpolyglutamate synthase -
Bacteroides fragilis
Length = 458
Score = 61.3 bits (142), Expect = 2e-08
Identities = 26/52 (50%), Positives = 38/52 (73%)
Frame = +3
Query: 336 IHVAGTKGKGSTSAMCDSILRHHGFRTGFFSSPHLIAVRERIRLDGKIVSEE 491
IH+AGT GKGS S +IL+ G+R G ++SPHL+ RERIR++G+ + +E
Sbjct: 49 IHIAGTNGKGSCSHTLAAILQSAGYRVGLYTSPHLVDFRERIRINGEPIPQE 100
>UniRef50_Q5SLF0 Cluster: Folyl-polyglutamate synthetase; n=4;
Deinococci|Rep: Folyl-polyglutamate synthetase - Thermus
thermophilus (strain HB8 / ATCC 27634 / DSM 579)
Length = 414
Score = 61.3 bits (142), Expect = 2e-08
Identities = 33/84 (39%), Positives = 47/84 (55%)
Frame = +3
Query: 243 RTGKRCTNLEDMERYLFRTGVTLTKLDELSVIHVAGTKGKGSTSAMCDSILRHHGFRTGF 422
R G+ LE + +L R G + V V GT GKG+T+ +IL GFR G
Sbjct: 10 RQGRFAPGLERIRAFLARLG---HPEEAYPVALVGGTNGKGTTARALAAILEEAGFRVGL 66
Query: 423 FSSPHLIAVRERIRLDGKIVSEEK 494
++SPHL+ RERI++ G+ + EEK
Sbjct: 67 YTSPHLVDFRERIQVQGRPIPEEK 90
>UniRef50_Q31HH1 Cluster: FolC bifunctional folylpolyglutamate
synthase/dihydrofolate synthase; n=1; Thiomicrospira
crunogena XCL-2|Rep: FolC bifunctional
folylpolyglutamate synthase/dihydrofolate synthase -
Thiomicrospira crunogena (strain XCL-2)
Length = 425
Score = 61.3 bits (142), Expect = 2e-08
Identities = 27/59 (45%), Positives = 39/59 (66%)
Frame = +3
Query: 333 VIHVAGTKGKGSTSAMCDSILRHHGFRTGFFSSPHLIAVRERIRLDGKIVSEEKFAQHF 509
VI VAGT GKGS+ AM SI G++ G ++SPHL+ ERIR+ G++ +++ Q F
Sbjct: 47 VISVAGTNGKGSSVAMLSSIYEASGYQVGVYTSPHLLHFNERIRVQGQLADDQQIVQAF 105
>UniRef50_Q1N6P7 Cluster: Folylpolyglutamate synthetase; n=1;
Oceanobacter sp. RED65|Rep: Folylpolyglutamate
synthetase - Oceanobacter sp. RED65
Length = 422
Score = 61.3 bits (142), Expect = 2e-08
Identities = 31/87 (35%), Positives = 47/87 (54%), Gaps = 4/87 (4%)
Frame = +3
Query: 270 EDMERYLFRTGVTLTKLDELS----VIHVAGTKGKGSTSAMCDSILRHHGFRTGFFSSPH 437
+D++ L R +LD + V+ VAGT GKG+T A C + R GF G F+SPH
Sbjct: 18 KDIDLGLDRVRAVAERLDLIKPAKYVVLVAGTNGKGTTVATCGELFRQSGFSVGVFTSPH 77
Query: 438 LIAVRERIRLDGKIVSEEKFAQHFHRV 518
+ ER+ ++GK VS+ + F +
Sbjct: 78 ITKYNERVSINGKQVSDAQLIDSFEAI 104
>UniRef50_Q18QE7 Cluster: FolC bifunctional protein; n=5;
Clostridia|Rep: FolC bifunctional protein -
Desulfitobacterium hafniense (strain DCB-2)
Length = 454
Score = 61.3 bits (142), Expect = 2e-08
Identities = 26/54 (48%), Positives = 37/54 (68%)
Frame = +3
Query: 321 DELSVIHVAGTKGKGSTSAMCDSILRHHGFRTGFFSSPHLIAVRERIRLDGKIV 482
+ L V+H+ GT GKGST+ M IL G+R G F+SPHL RERI ++G+++
Sbjct: 57 ERLRVVHIGGTNGKGSTTMMTAEILEDAGYRVGVFTSPHLHDYRERITINGEMI 110
>UniRef50_Q88ST5 Cluster: Folylpolyglutamate synthase; n=1;
Lactobacillus plantarum|Rep: Folylpolyglutamate synthase
- Lactobacillus plantarum
Length = 454
Score = 60.9 bits (141), Expect = 2e-08
Identities = 28/62 (45%), Positives = 40/62 (64%)
Frame = +3
Query: 333 VIHVAGTKGKGSTSAMCDSILRHHGFRTGFFSSPHLIAVRERIRLDGKIVSEEKFAQHFH 512
VIH+AGT GKGST AM SILR G++ G FSSP + RE+++ +G +S +F +
Sbjct: 48 VIHIAGTNGKGSTGAMLASILRAQGYQVGRFSSPAINDAREQLQCNGTWISPAEFIDTYR 107
Query: 513 RV 518
+
Sbjct: 108 EI 109
>UniRef50_Q0AWF7 Cluster: Putative uncharacterized protein; n=1;
Syntrophomonas wolfei subsp. wolfei str. Goettingen|Rep:
Putative uncharacterized protein - Syntrophomonas wolfei
subsp. wolfei (strain Goettingen)
Length = 416
Score = 60.9 bits (141), Expect = 2e-08
Identities = 26/64 (40%), Positives = 40/64 (62%)
Frame = +3
Query: 327 LSVIHVAGTKGKGSTSAMCDSILRHHGFRTGFFSSPHLIAVRERIRLDGKIVSEEKFAQH 506
L +H+AGT GKGSTS + ++L G+R G F SPH+ + RER ++ + EE+F +
Sbjct: 27 LKTVHIAGTNGKGSTSFILSAVLSQAGYRVGRFISPHIHSYRERFTINDTFIEEEEFLFY 86
Query: 507 FHRV 518
+V
Sbjct: 87 MAQV 90
>UniRef50_A6D0N3 Cluster: Folylpolyglutamate synthase; n=1; Vibrio
shilonii AK1|Rep: Folylpolyglutamate synthase - Vibrio
shilonii AK1
Length = 426
Score = 60.9 bits (141), Expect = 2e-08
Identities = 28/60 (46%), Positives = 40/60 (66%)
Frame = +3
Query: 330 SVIHVAGTKGKGSTSAMCDSILRHHGFRTGFFSSPHLIAVRERIRLDGKIVSEEKFAQHF 509
+VI VAGT GKGST A+ ++IL G+ G +SSPHLI ER+R++G + +E + F
Sbjct: 50 TVITVAGTNGKGSTCALMEAILLDAGYSVGVYSSPHLIRYNERVRVNGSDLPDESHTRAF 109
>UniRef50_A3VQ98 Cluster: FolC bifunctional protein; n=1;
Parvularcula bermudensis HTCC2503|Rep: FolC bifunctional
protein - Parvularcula bermudensis HTCC2503
Length = 443
Score = 60.9 bits (141), Expect = 2e-08
Identities = 34/78 (43%), Positives = 46/78 (58%)
Frame = +3
Query: 267 LEDMERYLFRTGVTLTKLDELSVIHVAGTKGKGSTSAMCDSILRHHGFRTGFFSSPHLIA 446
L+ +E L R G +L V+HVAGT GKGST A SIL+ G + F+SPHL+
Sbjct: 30 LDRIEEALARLGNPHHRLPP--VLHVAGTNGKGSTCAFLGSILKAAGLKVHIFTSPHLVR 87
Query: 447 VRERIRLDGKIVSEEKFA 500
ERI L G+ +S++ A
Sbjct: 88 FNERITLAGEPISDDLLA 105
>UniRef50_A3TFM8 Cluster: Putative folylpolyglutamate synthase; n=1;
Janibacter sp. HTCC2649|Rep: Putative folylpolyglutamate
synthase - Janibacter sp. HTCC2649
Length = 466
Score = 60.9 bits (141), Expect = 2e-08
Identities = 28/62 (45%), Positives = 41/62 (66%)
Frame = +3
Query: 333 VIHVAGTKGKGSTSAMCDSILRHHGFRTGFFSSPHLIAVRERIRLDGKIVSEEKFAQHFH 512
VIH+ GT GK +T+ + +SILR G TG F+SPHL ++ ERI + G+ + EKF + +
Sbjct: 64 VIHLTGTNGKTTTARVIESILREMGLTTGRFTSPHLHSMLERISIGGRPIEAEKFLRSYA 123
Query: 513 RV 518
V
Sbjct: 124 EV 125
>UniRef50_Q73NR8 Cluster: Folylpolyglutamate synthetase, putative;
n=1; Treponema denticola|Rep: Folylpolyglutamate
synthetase, putative - Treponema denticola
Length = 450
Score = 60.5 bits (140), Expect = 3e-08
Identities = 26/66 (39%), Positives = 41/66 (62%)
Frame = +3
Query: 321 DELSVIHVAGTKGKGSTSAMCDSILRHHGFRTGFFSSPHLIAVRERIRLDGKIVSEEKFA 500
D+ IH+AG+KGKGS S M SIL+ G +TG ++SPH+ RER+ G +E ++
Sbjct: 42 DDFLSIHIAGSKGKGSVSTMIASILKEAGKKTGLYTSPHVSDFRERMTQAGSFFDDEAYS 101
Query: 501 QHFHRV 518
+ ++
Sbjct: 102 ASYKKI 107
>UniRef50_Q6FEE4 Cluster: Bifunctional protein [Includes:
folylpolyglutamate synthase (FPGS); dihydrofolate
synthase ]; n=3; Acinetobacter|Rep: Bifunctional protein
[Includes: folylpolyglutamate synthase (FPGS);
dihydrofolate synthase ] - Acinetobacter sp. (strain
ADP1)
Length = 428
Score = 60.5 bits (140), Expect = 3e-08
Identities = 30/75 (40%), Positives = 44/75 (58%)
Frame = +3
Query: 294 RTGVTLTKLDELSVIHVAGTKGKGSTSAMCDSILRHHGFRTGFFSSPHLIAVRERIRLDG 473
+ GVT T V VAGT GKGST+ SIL G+R G + SPH+ ER++L+G
Sbjct: 40 KLGVTQTSA---KVFTVAGTNGKGSTTTTLASILTEQGYRVGLYQSPHIYRFNERVKLNG 96
Query: 474 KIVSEEKFAQHFHRV 518
+ S+++ + F +V
Sbjct: 97 QEASDQQLIEAFVKV 111
>UniRef50_Q2JDQ6 Cluster: FolC bifunctional protein; n=2;
Frankia|Rep: FolC bifunctional protein - Frankia sp.
(strain CcI3)
Length = 445
Score = 60.5 bits (140), Expect = 3e-08
Identities = 37/116 (31%), Positives = 61/116 (52%)
Frame = +3
Query: 156 VKSNYEDAVHKLNKLQSNKSTIDQIRKDLRTGKRCTNLEDMERYLFRTGVTLTKLDELSV 335
VK YE A LN +T+D ++ + G+ +L+ M R G + +
Sbjct: 7 VKWTYESAWAALN------NTVDLEKQTMPAGRPVPSLDRMRELAGRLG---DPHRAVPL 57
Query: 336 IHVAGTKGKGSTSAMCDSILRHHGFRTGFFSSPHLIAVRERIRLDGKIVSEEKFAQ 503
IH+ GT GK ST+ + ++L G R G ++SPHL V ER+ +DG+ + +E+F +
Sbjct: 58 IHLTGTNGKTSTARIISALLGAAGLRVGLYTSPHLERVNERLVVDGRPIGDEEFGR 113
>UniRef50_Q3DZP5 Cluster: Folylpolyglutamate synthetase; n=2;
Chloroflexus|Rep: Folylpolyglutamate synthetase -
Chloroflexus aurantiacus J-10-fl
Length = 438
Score = 60.5 bits (140), Expect = 3e-08
Identities = 27/60 (45%), Positives = 42/60 (70%)
Frame = +3
Query: 324 ELSVIHVAGTKGKGSTSAMCDSILRHHGFRTGFFSSPHLIAVRERIRLDGKIVSEEKFAQ 503
+L+ + VAGTKGKGST A+ +++ R G R G ++SPHL + RERI++D + +S+ Q
Sbjct: 50 QLAAVVVAGTKGKGSTCALIEAMARAAGLRVGLWTSPHLSSYRERIQIDREPISQATLIQ 109
>UniRef50_Q12P54 Cluster: FolC bifunctional protein; n=6;
Shewanella|Rep: FolC bifunctional protein - Shewanella
denitrificans (strain OS217 / ATCC BAA-1090 / DSM 15013)
Length = 448
Score = 60.5 bits (140), Expect = 3e-08
Identities = 31/70 (44%), Positives = 40/70 (57%)
Frame = +3
Query: 309 LTKLDELSVIHVAGTKGKGSTSAMCDSILRHHGFRTGFFSSPHLIAVRERIRLDGKIVSE 488
L L VI VAGT GKG++ AM +S+L G R G +SSPHLI ER+R+ G S+
Sbjct: 60 LLDLAPAQVITVAGTNGKGTSCAMLESVLSFAGKRVGVYSSPHLIHYNERVRIQGVDASD 119
Query: 489 EKFAQHFHRV 518
E F +
Sbjct: 120 EALIAAFSAI 129
>UniRef50_A4RKT0 Cluster: Putative uncharacterized protein; n=1;
Magnaporthe grisea|Rep: Putative uncharacterized protein
- Magnaporthe grisea (Rice blast fungus) (Pyricularia
grisea)
Length = 510
Score = 60.5 bits (140), Expect = 3e-08
Identities = 38/101 (37%), Positives = 51/101 (50%), Gaps = 18/101 (17%)
Frame = +3
Query: 276 MERYLFRTGVTLTKLDELSVIHVAGTKGKGSTSAMCDSILRHH----------------- 404
M +L G TK VIHV GTKGKG T A D +LR H
Sbjct: 40 MREWLTALGHDRTKTP-FDVIHVTGTKGKGGTCAWTDGLLRAHLKARAAGPRAAPGAQQN 98
Query: 405 -GFRTGFFSSPHLIAVRERIRLDGKIVSEEKFAQHFHRVYN 524
+ G ++SPH+++ RERIR+D VSE+ F +HF V++
Sbjct: 99 QQLKVGLYTSPHIVSERERIRIDFAPVSEDTFTRHFFEVWD 139
>UniRef50_Q30WU4 Cluster: FolC bifunctional protein; n=1;
Desulfovibrio desulfuricans G20|Rep: FolC bifunctional
protein - Desulfovibrio desulfuricans (strain G20)
Length = 435
Score = 60.1 bits (139), Expect = 4e-08
Identities = 28/56 (50%), Positives = 35/56 (62%)
Frame = +3
Query: 324 ELSVIHVAGTKGKGSTSAMCDSILRHHGFRTGFFSSPHLIAVRERIRLDGKIVSEE 491
E V+ V GT GKGST+ SI GF TG F SPH I RER+ +DG+++ EE
Sbjct: 55 EYPVVQVVGTNGKGSTATFMASIATGAGFSTGLFISPHFITPRERVLVDGEMLPEE 110
>UniRef50_Q5CBK3 Cluster: Folylpolyglutamate synthase/dihydrofolate
synthase; n=7; Thermotoga|Rep: Folylpolyglutamate
synthase/dihydrofolate synthase - Thermotoga petrophila
Length = 437
Score = 60.1 bits (139), Expect = 4e-08
Identities = 28/61 (45%), Positives = 38/61 (62%)
Frame = +3
Query: 336 IHVAGTKGKGSTSAMCDSILRHHGFRTGFFSSPHLIAVRERIRLDGKIVSEEKFAQHFHR 515
IHV GT GKGS + M IL G+R G + SPHL RERIRL+ + +SEE + + +
Sbjct: 50 IHVGGTNGKGSVTNMISHILISQGYRVGSYYSPHLSTFRERIRLNEEYISEEDVVKIYEK 109
Query: 516 V 518
+
Sbjct: 110 M 110
>UniRef50_A1HP48 Cluster: FolC bifunctional protein; n=1;
Thermosinus carboxydivorans Nor1|Rep: FolC bifunctional
protein - Thermosinus carboxydivorans Nor1
Length = 429
Score = 60.1 bits (139), Expect = 4e-08
Identities = 26/55 (47%), Positives = 38/55 (69%)
Frame = +3
Query: 336 IHVAGTKGKGSTSAMCDSILRHHGFRTGFFSSPHLIAVRERIRLDGKIVSEEKFA 500
+HV GT GKGST+AM +IL+ G +TG ++SPHL+ ER+ +DG+ + FA
Sbjct: 42 VHVTGTNGKGSTTAMLAAILQASGIKTGMYTSPHLVDYTERMVVDGRPAAPAAFA 96
>UniRef50_Q6B7M6 Cluster: FolC-P protein; n=1; Haloferax
volcanii|Rep: FolC-P protein - Halobacterium volcanii
(Haloferax volcanii)
Length = 838
Score = 60.1 bits (139), Expect = 4e-08
Identities = 32/80 (40%), Positives = 46/80 (57%)
Frame = +3
Query: 237 DLRTGKRCTNLEDMERYLFRTGVTLTKLDELSVIHVAGTKGKGSTSAMCDSILRHHGFRT 416
DLR + E + R L G + +S + VAG+ GKGST+ M D++LR G
Sbjct: 12 DLRRFQVKPGTESIRRLLSHLG---DPHEGVSFVQVAGSNGKGSTARMVDAMLRESGAHV 68
Query: 417 GFFSSPHLIAVRERIRLDGK 476
G ++SPH VRER+R+DG+
Sbjct: 69 GLYTSPHFDDVRERVRVDGR 88
>UniRef50_Q2RZW2 Cluster: Dihydrofolate synthetase; n=1;
Salinibacter ruber DSM 13855|Rep: Dihydrofolate
synthetase - Salinibacter ruber (strain DSM 13855)
Length = 435
Score = 59.7 bits (138), Expect = 5e-08
Identities = 28/54 (51%), Positives = 36/54 (66%)
Frame = +3
Query: 312 TKLDELSVIHVAGTKGKGSTSAMCDSILRHHGFRTGFFSSPHLIAVRERIRLDG 473
T + L +HVAGT GKGST+AM +I G RTG +SPHL V +R+R+DG
Sbjct: 38 TPHEALRAVHVAGTNGKGSTAAMTAAIATAAGLRTGLHTSPHLTHVAQRMRVDG 91
>UniRef50_Q0A999 Cluster: FolC bifunctional protein; n=1;
Alkalilimnicola ehrlichei MLHE-1|Rep: FolC bifunctional
protein - Alkalilimnicola ehrlichei (strain MLHE-1)
Length = 437
Score = 59.7 bits (138), Expect = 5e-08
Identities = 31/62 (50%), Positives = 39/62 (62%)
Frame = +3
Query: 333 VIHVAGTKGKGSTSAMCDSILRHHGFRTGFFSSPHLIAVRERIRLDGKIVSEEKFAQHFH 512
VI VAGT GKGS A +++L G+RT ++SPHL+ ERIRL G VS+E F
Sbjct: 57 VITVAGTNGKGSCIAYLEAMLGAAGYRTAAYTSPHLLRYNERIRLAGVPVSDEAITAAFS 116
Query: 513 RV 518
RV
Sbjct: 117 RV 118
>UniRef50_A6FEP3 Cluster: Dihydrofolate synthase /
folylpolyglutamate synthase; n=1; Moritella sp.
PE36|Rep: Dihydrofolate synthase / folylpolyglutamate
synthase - Moritella sp. PE36
Length = 441
Score = 59.7 bits (138), Expect = 5e-08
Identities = 29/59 (49%), Positives = 38/59 (64%)
Frame = +3
Query: 333 VIHVAGTKGKGSTSAMCDSILRHHGFRTGFFSSPHLIAVRERIRLDGKIVSEEKFAQHF 509
VI VAGT GKGST A + IL GF G SSPH+ RER+R++GK+++ + A F
Sbjct: 49 VITVAGTNGKGSTCAFLERILLDAGFNVGVTSSPHIQDYRERVRVNGKMLTAQAHADSF 107
>UniRef50_A6DMK1 Cluster: Folylpolyglutamate synthase; n=1;
Lentisphaera araneosa HTCC2155|Rep: Folylpolyglutamate
synthase - Lentisphaera araneosa HTCC2155
Length = 423
Score = 59.7 bits (138), Expect = 5e-08
Identities = 26/64 (40%), Positives = 40/64 (62%)
Frame = +3
Query: 327 LSVIHVAGTKGKGSTSAMCDSILRHHGFRTGFFSSPHLIAVRERIRLDGKIVSEEKFAQH 506
L +HVAGT GKGST AM + ++ G +TGF+SSP L+ ER R++G ++E +
Sbjct: 43 LKFVHVAGTNGKGSTCAMIATACKYAGLKTGFYSSPFLVNFLERWRINGSPINESIYLDA 102
Query: 507 FHRV 518
++
Sbjct: 103 MQKI 106
>UniRef50_A3JGB7 Cluster: Folylpolyglutamate synthetase; n=3;
Marinobacter|Rep: Folylpolyglutamate synthetase -
Marinobacter sp. ELB17
Length = 445
Score = 59.7 bits (138), Expect = 5e-08
Identities = 35/86 (40%), Positives = 50/86 (58%), Gaps = 4/86 (4%)
Frame = +3
Query: 273 DMERYLFRTGVTLTKL----DELSVIHVAGTKGKGSTSAMCDSILRHHGFRTGFFSSPHL 440
++E L R V L +L E +I VAGT GKGST A +++L+ G RT ++SPHL
Sbjct: 37 EIELGLDRVMVVLQRLFPGKPEARIITVAGTNGKGSTVAALEALLQEAGRRTAAYTSPHL 96
Query: 441 IAVRERIRLDGKIVSEEKFAQHFHRV 518
ER+RL G+ +S+ + F RV
Sbjct: 97 QVYNERVRLLGEQISDAQMIYGFERV 122
>UniRef50_A5K2Z0 Cluster: Dihydrofolate synthase/folylpolyglutamate
synthase, putative; n=1; Plasmodium vivax|Rep:
Dihydrofolate synthase/folylpolyglutamate synthase,
putative - Plasmodium vivax
Length = 535
Score = 59.7 bits (138), Expect = 5e-08
Identities = 26/57 (45%), Positives = 36/57 (63%)
Frame = +3
Query: 321 DELSVIHVAGTKGKGSTSAMCDSILRHHGFRTGFFSSPHLIAVRERIRLDGKIVSEE 491
D IHVAGT GKGS L+ +R G F+SPH+ ++RERI++D + +SEE
Sbjct: 45 DSYKTIHVAGTNGKGSVCHKISVSLKLRNYRVGLFTSPHVFSLRERIKVDDECISEE 101
>UniRef50_Q758R3 Cluster: AEL310Cp; n=1; Eremothecium gossypii|Rep:
AEL310Cp - Ashbya gossypii (Yeast) (Eremothecium
gossypii)
Length = 406
Score = 59.7 bits (138), Expect = 5e-08
Identities = 26/60 (43%), Positives = 39/60 (65%)
Frame = +3
Query: 321 DELSVIHVAGTKGKGSTSAMCDSILRHHGFRTGFFSSPHLIAVRERIRLDGKIVSEEKFA 500
+ + V+HVAGT GKGS A ++LR G R G F+SPHL+ R+ I +DG+++ +A
Sbjct: 20 ERMRVLHVAGTNGKGSVCAYLAAVLRAGGERVGRFTSPHLVHPRDAITVDGEVIGAATYA 79
>UniRef50_Q8KFQ9 Cluster: Folylpolyglutamate synthase; n=1;
Chlorobaculum tepidum|Rep: Folylpolyglutamate synthase -
Chlorobium tepidum
Length = 392
Score = 59.3 bits (137), Expect = 6e-08
Identities = 25/57 (43%), Positives = 39/57 (68%)
Frame = +3
Query: 336 IHVAGTKGKGSTSAMCDSILRHHGFRTGFFSSPHLIAVRERIRLDGKIVSEEKFAQH 506
+HVAGT GKG+ ++ SI G +TG F+SPHL+ ERIR+DG+ + + + A++
Sbjct: 1 MHVAGTNGKGTVASCVASIFSTSGRKTGLFTSPHLVDFTERIRIDGQQIGQARVAEY 57
>UniRef50_Q5C3N8 Cluster: SJCHGC04288 protein; n=1; Schistosoma
japonicum|Rep: SJCHGC04288 protein - Schistosoma
japonicum (Blood fluke)
Length = 154
Score = 59.3 bits (137), Expect = 6e-08
Identities = 28/48 (58%), Positives = 34/48 (70%)
Frame = +3
Query: 378 MCDSILRHHGFRTGFFSSPHLIAVRERIRLDGKIVSEEKFAQHFHRVY 521
M +SILR GF TGF SSPHLI V ERIR+DG+ +S + FA F V+
Sbjct: 1 MIESILRKSGFHTGFLSSPHLINVEERIRIDGQPISRDHFADVFWDVH 48
>UniRef50_Q9PC39 Cluster: Folylpolyglutamate synthase/dihydrofolate
synthase; n=13; Proteobacteria|Rep: Folylpolyglutamate
synthase/dihydrofolate synthase - Xylella fastidiosa
Length = 441
Score = 58.8 bits (136), Expect = 8e-08
Identities = 27/61 (44%), Positives = 38/61 (62%)
Frame = +3
Query: 336 IHVAGTKGKGSTSAMCDSILRHHGFRTGFFSSPHLIAVRERIRLDGKIVSEEKFAQHFHR 515
I V GT GKGST +SI R G++ G ++SPHL+ ER+R+DG+ V + + F R
Sbjct: 55 IVVGGTNGKGSTVTFIESIARAAGWKVGTYTSPHLMRYNERVRIDGREVDDALLVEAFSR 114
Query: 516 V 518
V
Sbjct: 115 V 115
>UniRef50_Q6AJ73 Cluster: Related to folylpolyglutamate synthase;
n=3; Deltaproteobacteria|Rep: Related to
folylpolyglutamate synthase - Desulfotalea psychrophila
Length = 441
Score = 58.8 bits (136), Expect = 8e-08
Identities = 25/59 (42%), Positives = 39/59 (66%)
Frame = +3
Query: 324 ELSVIHVAGTKGKGSTSAMCDSILRHHGFRTGFFSSPHLIAVRERIRLDGKIVSEEKFA 500
++ V+HVAGT GKGS + S+L G++ G ++SPHL + RER R++ + +S FA
Sbjct: 49 KMKVVHVAGTNGKGSVCSSLVSVLAKGGYQLGLYTSPHLSSPRERFRINDEYISRADFA 107
>UniRef50_Q604P6 Cluster: Folylpolyglutamate synthase/dihydrofolate
synthase; n=2; Proteobacteria|Rep: Folylpolyglutamate
synthase/dihydrofolate synthase - Methylococcus
capsulatus
Length = 431
Score = 58.8 bits (136), Expect = 8e-08
Identities = 28/66 (42%), Positives = 37/66 (56%)
Frame = +3
Query: 321 DELSVIHVAGTKGKGSTSAMCDSILRHHGFRTGFFSSPHLIAVRERIRLDGKIVSEEKFA 500
D I V GT GKGS A D+ILR G+R G ++SPH++ ERI +DG V +
Sbjct: 40 DRPFTITVGGTNGKGSCVAALDTILRRAGYRVGAYTSPHILRYNERICIDGTPVDDAAIC 99
Query: 501 QHFHRV 518
F R+
Sbjct: 100 ASFERI 105
>UniRef50_Q1WT76 Cluster: Folylpolyglutamate synthase /
Dihydrofolate synthase; n=1; Lactobacillus salivarius
subsp. salivarius UCC118|Rep: Folylpolyglutamate
synthase / Dihydrofolate synthase - Lactobacillus
salivarius subsp. salivarius (strain UCC118)
Length = 433
Score = 58.8 bits (136), Expect = 8e-08
Identities = 28/84 (33%), Positives = 48/84 (57%)
Frame = +3
Query: 252 KRCTNLEDMERYLFRTGVTLTKLDELSVIHVAGTKGKGSTSAMCDSILRHHGFRTGFFSS 431
K+ L+ M ++ R G +++ IHV GT GKGST+A ++ G+ G F+S
Sbjct: 20 KKIPTLDRMRDFMKRLG---NPHEKVKAIHVTGTNGKGSTTAYLRDLIAEQGYNVGTFTS 76
Query: 432 PHLIAVRERIRLDGKIVSEEKFAQ 503
P + ERI ++GK++S+E+ +
Sbjct: 77 PFIEKFNERISVNGKMISDEEIVR 100
>UniRef50_A4A847 Cluster: Folylpolyglutamate synthase/dihydrofolate
synthase; n=1; Congregibacter litoralis KT71|Rep:
Folylpolyglutamate synthase/dihydrofolate synthase -
Congregibacter litoralis KT71
Length = 428
Score = 58.8 bits (136), Expect = 8e-08
Identities = 30/62 (48%), Positives = 39/62 (62%)
Frame = +3
Query: 333 VIHVAGTKGKGSTSAMCDSILRHHGFRTGFFSSPHLIAVRERIRLDGKIVSEEKFAQHFH 512
VI VAGT GKGS + ILR HG RTG ++SPHL++ ERI +DG VS+ + F
Sbjct: 44 VITVAGTNGKGSVVFGTECILRAHGRRTGRYTSPHLLSFNERIAVDGCPVSDGQIVAAFD 103
Query: 513 RV 518
+
Sbjct: 104 AI 105
>UniRef50_Q7NLP7 Cluster: Folylpolyglutamate synthase; n=1;
Gloeobacter violaceus|Rep: Folylpolyglutamate synthase -
Gloeobacter violaceus
Length = 413
Score = 58.4 bits (135), Expect = 1e-07
Identities = 26/51 (50%), Positives = 35/51 (68%)
Frame = +3
Query: 336 IHVAGTKGKGSTSAMCDSILRHHGFRTGFFSSPHLIAVRERIRLDGKIVSE 488
+HVAGT GKGS A IL+ G+RTG ++SPHL+ ERI +DG +S+
Sbjct: 39 VHVAGTNGKGSVCAYLSHILQTAGYRTGRYTSPHLLDWNERIWIDGAFISD 89
>UniRef50_Q74AI6 Cluster: FolC bifunctional protein; n=5;
Geobacter|Rep: FolC bifunctional protein - Geobacter
sulfurreducens
Length = 381
Score = 58.4 bits (135), Expect = 1e-07
Identities = 27/54 (50%), Positives = 36/54 (66%)
Frame = +3
Query: 342 VAGTKGKGSTSAMCDSILRHHGFRTGFFSSPHLIAVRERIRLDGKIVSEEKFAQ 503
+AGT GKGST+A SIL G+R G F+SPHL ER R++G ++EE A+
Sbjct: 1 MAGTNGKGSTAAFLASILAEGGYRAGLFTSPHLTRFTERFRINGTEIAEEAAAR 54
>UniRef50_Q2JLQ4 Cluster: Folylpolyglutamate synthase; n=2;
Synechococcus|Rep: Folylpolyglutamate synthase -
Synechococcus sp. (strain JA-2-3B'a(2-13))
(Cyanobacteria bacteriumYellowstone B-Prime)
Length = 433
Score = 58.4 bits (135), Expect = 1e-07
Identities = 28/64 (43%), Positives = 40/64 (62%)
Frame = +3
Query: 327 LSVIHVAGTKGKGSTSAMCDSILRHHGFRTGFFSSPHLIAVRERIRLDGKIVSEEKFAQH 506
+ IHVAGT GKGS A +L G+R G ++SPHL+ RERI L+G+ +S ++Q
Sbjct: 46 IPAIHVAGTNGKGSVCAWVSHVLWAAGYRVGRYTSPHLVDWRERIWLNGEYISANDWSQA 105
Query: 507 FHRV 518
+V
Sbjct: 106 LAQV 109
>UniRef50_Q6M382 Cluster: FOLYLPOLYGLUTAMATE SYNTHASE; n=32;
Actinomycetales|Rep: FOLYLPOLYGLUTAMATE SYNTHASE -
Corynebacterium glutamicum (Brevibacterium flavum)
Length = 507
Score = 58.4 bits (135), Expect = 1e-07
Identities = 29/61 (47%), Positives = 38/61 (62%)
Frame = +3
Query: 336 IHVAGTKGKGSTSAMCDSILRHHGFRTGFFSSPHLIAVRERIRLDGKIVSEEKFAQHFHR 515
IHVAGT GK ST+ M +S+LR RTG +SPHL V ERI +DGK + F + +
Sbjct: 93 IHVAGTNGKTSTTRMIESLLRAFHRRTGRTTSPHLQLVTERIAIDGKPIHPRDFVRIYEE 152
Query: 516 V 518
+
Sbjct: 153 I 153
>UniRef50_A5ZWM5 Cluster: Putative uncharacterized protein; n=1;
Ruminococcus obeum ATCC 29174|Rep: Putative
uncharacterized protein - Ruminococcus obeum ATCC 29174
Length = 137
Score = 58.4 bits (135), Expect = 1e-07
Identities = 28/66 (42%), Positives = 40/66 (60%)
Frame = +3
Query: 321 DELSVIHVAGTKGKGSTSAMCDSILRHHGFRTGFFSSPHLIAVRERIRLDGKIVSEEKFA 500
D+L +HVAGT GKGS A + L G+R G + SP + + RE++ + G VS E+FA
Sbjct: 38 DQLKYVHVAGTNGKGSVIAYLYTTLSEAGYRVGRYISPSVYSYREKMEVAGSAVSREQFA 97
Query: 501 QHFHRV 518
+ RV
Sbjct: 98 GYVTRV 103
>UniRef50_A4BRV9 Cluster: Folylpolyglutamate synthase/dihydrofolate
synthase; n=1; Nitrococcus mobilis Nb-231|Rep:
Folylpolyglutamate synthase/dihydrofolate synthase -
Nitrococcus mobilis Nb-231
Length = 426
Score = 58.4 bits (135), Expect = 1e-07
Identities = 28/62 (45%), Positives = 38/62 (61%)
Frame = +3
Query: 333 VIHVAGTKGKGSTSAMCDSILRHHGFRTGFFSSPHLIAVRERIRLDGKIVSEEKFAQHFH 512
VI V GT GKGST A +++LR G+ G +SSPH+ ERIR+DG+ ++E F
Sbjct: 44 VITVGGTNGKGSTVAYLEAMLRALGYHPGVYSSPHVQRYNERIRIDGREATDEAIVAAFE 103
Query: 513 RV 518
V
Sbjct: 104 AV 105
>UniRef50_Q0BWJ9 Cluster: Putative folylpolyglutamate synthase; n=1;
Hyphomonas neptunium ATCC 15444|Rep: Putative
folylpolyglutamate synthase - Hyphomonas neptunium
(strain ATCC 15444)
Length = 417
Score = 58.0 bits (134), Expect = 1e-07
Identities = 27/52 (51%), Positives = 34/52 (65%)
Frame = +3
Query: 333 VIHVAGTKGKGSTSAMCDSILRHHGFRTGFFSSPHLIAVRERIRLDGKIVSE 488
VIHVAGT GKGST A ++ G + F+SPHL+ ERIRL GK+V +
Sbjct: 47 VIHVAGTNGKGSTCAFMRAMAEAAGLKVHVFTSPHLVRFNERIRLAGKLVED 98
>UniRef50_P43775 Cluster: Folylpolyglutamate synthase; n=101;
Gammaproteobacteria|Rep: Folylpolyglutamate synthase -
Haemophilus influenzae
Length = 437
Score = 58.0 bits (134), Expect = 1e-07
Identities = 25/59 (42%), Positives = 37/59 (62%)
Frame = +3
Query: 333 VIHVAGTKGKGSTSAMCDSILRHHGFRTGFFSSPHLIAVRERIRLDGKIVSEEKFAQHF 509
VI V GT GKG+T + ++IL +HG R G +SSPHL+ ER+R+ + + +E F
Sbjct: 50 VITVGGTNGKGTTCRLLETILLNHGLRVGVYSSPHLLRYNERVRIQNQDLPDEAHTASF 108
>UniRef50_Q9HZA8 Cluster: Folylpolyglutamate synthetase; n=18;
Pseudomonadaceae|Rep: Folylpolyglutamate synthetase -
Pseudomonas aeruginosa
Length = 429
Score = 57.6 bits (133), Expect = 2e-07
Identities = 26/62 (41%), Positives = 35/62 (56%)
Frame = +3
Query: 333 VIHVAGTKGKGSTSAMCDSILRHHGFRTGFFSSPHLIAVRERIRLDGKIVSEEKFAQHFH 512
V+ V GT GKGST A+ +LR G G +SSPHL+ ER+R+DG + + F
Sbjct: 44 VVTVTGTNGKGSTCALLAELLREQGLSVGVYSSPHLLRYNERVRIDGIEAGDAQLCDAFS 103
Query: 513 RV 518
V
Sbjct: 104 AV 105
>UniRef50_Q2BMN3 Cluster: Folylpolyglutamate synthase; n=1;
Neptuniibacter caesariensis|Rep: Folylpolyglutamate
synthase - Neptuniibacter caesariensis
Length = 419
Score = 57.6 bits (133), Expect = 2e-07
Identities = 26/67 (38%), Positives = 39/67 (58%)
Frame = +3
Query: 318 LDELSVIHVAGTKGKGSTSAMCDSILRHHGFRTGFFSSPHLIAVRERIRLDGKIVSEEKF 497
L +V+ VAGT GKGST + SI G+ G ++SPH + ER+RL+G ++E+
Sbjct: 40 LSSSTVVTVAGTNGKGSTVSYLSSIYLQAGYSVGAYTSPHFLRYNERVRLNGLEATDEQL 99
Query: 498 AQHFHRV 518
F R+
Sbjct: 100 CDAFERI 106
>UniRef50_A0W7P3 Cluster: FolC bifunctional protein precursor; n=2;
Desulfuromonadales|Rep: FolC bifunctional protein
precursor - Geobacter lovleyi SZ
Length = 428
Score = 57.6 bits (133), Expect = 2e-07
Identities = 24/48 (50%), Positives = 34/48 (70%)
Frame = +3
Query: 330 SVIHVAGTKGKGSTSAMCDSILRHHGFRTGFFSSPHLIAVRERIRLDG 473
+ IHV GT GKGST+A +I+ G+ TG F+SPHL++ ER R++G
Sbjct: 40 AAIHVVGTNGKGSTAAFLAAIIEQAGYCTGLFTSPHLVSYTERFRVNG 87
>UniRef50_Q5KCY2 Cluster: Dihydrofolate synthase, putative; n=1;
Filobasidiella neoformans|Rep: Dihydrofolate synthase,
putative - Cryptococcus neoformans (Filobasidiella
neoformans)
Length = 536
Score = 57.6 bits (133), Expect = 2e-07
Identities = 29/73 (39%), Positives = 44/73 (60%), Gaps = 2/73 (2%)
Frame = +3
Query: 261 TNLEDMERYLFRTGVTLTKLDELSV--IHVAGTKGKGSTSAMCDSILRHHGFRTGFFSSP 434
T L +++ L R + ++ L V IH+AGT GKGS SA+ +S GFR ++SP
Sbjct: 48 TGLGEIDLGLLRMQILISAFPPLLVPAIHLAGTNGKGSVSALLESCFLSAGFRVARYNSP 107
Query: 435 HLIAVRERIRLDG 473
HL+ R+ +R+DG
Sbjct: 108 HLLEPRDALRIDG 120
>UniRef50_UPI00005100A3 Cluster: COG0285: Folylpolyglutamate
synthase; n=1; Brevibacterium linens BL2|Rep: COG0285:
Folylpolyglutamate synthase - Brevibacterium linens BL2
Length = 462
Score = 57.2 bits (132), Expect = 3e-07
Identities = 29/57 (50%), Positives = 36/57 (63%)
Frame = +3
Query: 333 VIHVAGTKGKGSTSAMCDSILRHHGFRTGFFSSPHLIAVRERIRLDGKIVSEEKFAQ 503
VI V GT GK ST+ M D+I+ H R G F+SPHL +V ERI +DG V E F +
Sbjct: 53 VITVTGTNGKTSTARMIDAIVTAHDLRVGRFTSPHLHSVTERISVDGGPVPAETFVR 109
>UniRef50_Q5QWH7 Cluster: Folylpolyglutamate synthase; n=2;
Idiomarina|Rep: Folylpolyglutamate synthase - Idiomarina
loihiensis
Length = 430
Score = 57.2 bits (132), Expect = 3e-07
Identities = 24/62 (38%), Positives = 41/62 (66%)
Frame = +3
Query: 333 VIHVAGTKGKGSTSAMCDSILRHHGFRTGFFSSPHLIAVRERIRLDGKIVSEEKFAQHFH 512
VI V+GT GKGST ++IL+ G+ TG ++SPH+ RER+R++ + + + + + FH
Sbjct: 53 VITVSGTNGKGSTVCYLETILQAAGYTTGVYTSPHITEYRERVRVNAQELPDSEHVKAFH 112
Query: 513 RV 518
+
Sbjct: 113 AI 114
>UniRef50_Q03Z01 Cluster: Folylpolyglutamate synthase; n=1;
Leuconostoc mesenteroides subsp. mesenteroides ATCC
8293|Rep: Folylpolyglutamate synthase - Leuconostoc
mesenteroides subsp. mesenteroides (strain ATCC 8293
/NCDO 523)
Length = 393
Score = 57.2 bits (132), Expect = 3e-07
Identities = 26/61 (42%), Positives = 39/61 (63%)
Frame = +3
Query: 336 IHVAGTKGKGSTSAMCDSILRHHGFRTGFFSSPHLIAVRERIRLDGKIVSEEKFAQHFHR 515
IHV GT GKGS S M +ILR G+ TG F SP + RERI+++ +++S++ ++
Sbjct: 44 IHVTGTNGKGSVSTMASNILRVAGYDTGLFVSPFITNFRERIQINNEMISKDDLLHATNK 103
Query: 516 V 518
V
Sbjct: 104 V 104
>UniRef50_A1ZCQ8 Cluster: Folylpolyglutamate synthase; n=1;
Microscilla marina ATCC 23134|Rep: Folylpolyglutamate
synthase - Microscilla marina ATCC 23134
Length = 428
Score = 57.2 bits (132), Expect = 3e-07
Identities = 27/84 (32%), Positives = 50/84 (59%)
Frame = +3
Query: 264 NLEDMERYLFRTGVTLTKLDELSVIHVAGTKGKGSTSAMCDSILRHHGFRTGFFSSPHLI 443
+L+++ R+ G T+ L H+AGT GKGS+S M ++L+ G++ G ++SPHL
Sbjct: 28 SLDNIRRFCAHLGNPHTQYPTL---HIAGTNGKGSSSHMLAAVLQAAGYKVGLYTSPHLK 84
Query: 444 AVRERIRLDGKIVSEEKFAQHFHR 515
+ ER+R++G+ ++ + R
Sbjct: 85 SFTERVRVNGQAIAPAQIVAFVQR 108
>UniRef50_A6SPC7 Cluster: Putative uncharacterized protein; n=2;
Sclerotiniaceae|Rep: Putative uncharacterized protein -
Botryotinia fuckeliana B05.10
Length = 510
Score = 57.2 bits (132), Expect = 3e-07
Identities = 29/72 (40%), Positives = 45/72 (62%), Gaps = 6/72 (8%)
Frame = +3
Query: 324 ELSVIHVAGTKGKGSTSAMCDSILRHHGFRTG------FFSSPHLIAVRERIRLDGKIVS 485
+ VIH+AGTKGK ST S L + RTG +++P+ +RE I+++ K VS
Sbjct: 81 DFDVIHIAGTKGKASTCMFVKSFLSSYASRTGVVKKIGLYTNPYSPNIREPIKINAKPVS 140
Query: 486 EEKFAQHFHRVY 521
E+KFA++F +V+
Sbjct: 141 EDKFARYFFQVW 152
>UniRef50_Q7VAS8 Cluster: Folylpolyglutamate synthase; n=3;
Prochlorococcus marinus|Rep: Folylpolyglutamate synthase
- Prochlorococcus marinus
Length = 411
Score = 56.8 bits (131), Expect = 3e-07
Identities = 26/65 (40%), Positives = 41/65 (63%)
Frame = +3
Query: 324 ELSVIHVAGTKGKGSTSAMCDSILRHHGFRTGFFSSPHLIAVRERIRLDGKIVSEEKFAQ 503
++ I +AGT GKGS + +S L +TG +SPHL++ ERIR+DG+++S EK +
Sbjct: 44 KVPAIQIAGTNGKGSITCFLESCLTKTHIKTGCTTSPHLVSWCERIRIDGQMISPEKLRK 103
Query: 504 HFHRV 518
+ V
Sbjct: 104 FVNEV 108
>UniRef50_Q3B220 Cluster: Folylpolyglutamate synthetase; n=7;
Chlorobium/Pelodictyon group|Rep: Folylpolyglutamate
synthetase - Pelodictyon luteolum (strain DSM 273)
(Chlorobium luteolum (strain DSM273))
Length = 443
Score = 56.8 bits (131), Expect = 3e-07
Identities = 24/58 (41%), Positives = 39/58 (67%)
Frame = +3
Query: 333 VIHVAGTKGKGSTSAMCDSILRHHGFRTGFFSSPHLIAVRERIRLDGKIVSEEKFAQH 506
V+HVAGT GKG+ ++ S+ G +T ++SPHL+ ERIR+DG+ + E+ A++
Sbjct: 52 VVHVAGTNGKGTAASAMASMFTAAGKKTALYTSPHLVDFTERIRIDGRRIPEDAAARY 109
>UniRef50_Q40KD4 Cluster: Folylpolyglutamate synthetase; n=12;
Rickettsiales|Rep: Folylpolyglutamate synthetase -
Ehrlichia chaffeensis str. Sapulpa
Length = 435
Score = 56.8 bits (131), Expect = 3e-07
Identities = 31/72 (43%), Positives = 42/72 (58%)
Frame = +3
Query: 276 MERYLFRTGVTLTKLDELSVIHVAGTKGKGSTSAMCDSILRHHGFRTGFFSSPHLIAVRE 455
M + L R G KL VIH+AGT GKGST + IL G +T ++SPHL+ E
Sbjct: 27 MRQLLDRLGNPEKKLPP--VIHIAGTNGKGSTISFIRYILNSAGLKTHIYTSPHLVEFNE 84
Query: 456 RIRLDGKIVSEE 491
R+ L GK +S++
Sbjct: 85 RVVLAGKRISDQ 96
>UniRef50_Q0P9G6 Cluster: Folylpolyglutamate synthase/dihydrofolate
synthase; n=12; Campylobacter|Rep: Folylpolyglutamate
synthase/dihydrofolate synthase - Campylobacter jejuni
Length = 394
Score = 56.8 bits (131), Expect = 3e-07
Identities = 28/86 (32%), Positives = 48/86 (55%), Gaps = 2/86 (2%)
Frame = +3
Query: 252 KRCTNLEDMERYL-FRTGVTLTK-LDELSVIHVAGTKGKGSTSAMCDSILRHHGFRTGFF 425
++ N + ++R+L FR K + +I + GT GKGST +L + ++ G +
Sbjct: 17 QKSINYDKIDRFLMFRMYEKYKKYFKNIPIIQLIGTNGKGSTGRYLTQLLENLNYKIGHY 76
Query: 426 SSPHLIAVRERIRLDGKIVSEEKFAQ 503
+SPH+ + ER LDGKI ++E+ Q
Sbjct: 77 TSPHIFSFNERFYLDGKIANDEELEQ 102
>UniRef50_A6Q510 Cluster: Folylpolyglutamate synthase; n=1;
Nitratiruptor sp. SB155-2|Rep: Folylpolyglutamate
synthase - Nitratiruptor sp. (strain SB155-2)
Length = 376
Score = 56.8 bits (131), Expect = 3e-07
Identities = 22/53 (41%), Positives = 35/53 (66%)
Frame = +3
Query: 333 VIHVAGTKGKGSTSAMCDSILRHHGFRTGFFSSPHLIAVRERIRLDGKIVSEE 491
+IH+ GT GKG+T +L+ G + G ++SPH++ ERI +DGK +S+E
Sbjct: 38 IIHIIGTNGKGTTGRFLAGMLKESGKKVGHYTSPHILHFHERIWIDGKFISDE 90
>UniRef50_A5Z386 Cluster: Putative uncharacterized protein; n=1;
Eubacterium ventriosum ATCC 27560|Rep: Putative
uncharacterized protein - Eubacterium ventriosum ATCC
27560
Length = 462
Score = 56.8 bits (131), Expect = 3e-07
Identities = 26/66 (39%), Positives = 40/66 (60%)
Frame = +3
Query: 321 DELSVIHVAGTKGKGSTSAMCDSILRHHGFRTGFFSSPHLIAVRERIRLDGKIVSEEKFA 500
+EL V+H+AGT GKGS +IL G++ G + SP + RE IR++ + +SEE+ A
Sbjct: 39 NELKVVHIAGTNGKGSIMTFVQNILMESGYKVGRYCSPAVFNEREIIRINDEYISEEQSA 98
Query: 501 QHFHRV 518
R+
Sbjct: 99 DLLTRI 104
>UniRef50_Q97SN7 Cluster: Dihydrofolate synthetase; n=15;
Streptococcus|Rep: Dihydrofolate synthetase -
Streptococcus pneumoniae
Length = 440
Score = 56.4 bits (130), Expect = 4e-07
Identities = 25/57 (43%), Positives = 37/57 (64%)
Frame = +3
Query: 324 ELSVIHVAGTKGKGSTSAMCDSILRHHGFRTGFFSSPHLIAVRERIRLDGKIVSEEK 494
+L V+H+ GT GKGST A +L G R G FSSP+LI ++I ++G+ +SE +
Sbjct: 38 KLKVLHIGGTNGKGSTIAFLKKMLEKLGLRVGVFSSPYLIHYTDQISINGESISEAR 94
>UniRef50_Q8EPN5 Cluster: Folyl-polyglutamate synthase; n=1;
Oceanobacillus iheyensis|Rep: Folyl-polyglutamate
synthase - Oceanobacillus iheyensis
Length = 426
Score = 56.4 bits (130), Expect = 4e-07
Identities = 26/65 (40%), Positives = 41/65 (63%)
Frame = +3
Query: 324 ELSVIHVAGTKGKGSTSAMCDSILRHHGFRTGFFSSPHLIAVRERIRLDGKIVSEEKFAQ 503
+L IH+AGT GKGSTS S L + ++ G F+SP +R I+++ + VSE+ F+Q
Sbjct: 38 DLPTIHIAGTNGKGSTSQFIQSALIANDYKVGSFTSPSFYGIRGFIQMNNEPVSEKVFSQ 97
Query: 504 HFHRV 518
F ++
Sbjct: 98 AFQKM 102
>UniRef50_Q7VRV1 Cluster: Folylpolyglutamate synthase; n=2;
Candidatus Blochmannia|Rep: Folylpolyglutamate synthase
- Blochmannia floridanus
Length = 415
Score = 56.4 bits (130), Expect = 4e-07
Identities = 24/60 (40%), Positives = 39/60 (65%)
Frame = +3
Query: 324 ELSVIHVAGTKGKGSTSAMCDSILRHHGFRTGFFSSPHLIAVRERIRLDGKIVSEEKFAQ 503
E+ + V GT GKG+T + +SIL H + G ++SPHL+ ERIR+ G+++S++ Q
Sbjct: 41 EIYTVLVGGTNGKGTTCFLLESILLHSDIKVGLYTSPHLLFYNERIRVCGQVLSDDVHIQ 100
>UniRef50_Q1JHI7 Cluster: Folylpolyglutamate synthase /
Dihydrofolate synthase; n=15; Streptococcus|Rep:
Folylpolyglutamate synthase / Dihydrofolate synthase -
Streptococcus pyogenes serotype M2 (strain MGAS10270)
Length = 430
Score = 56.4 bits (130), Expect = 4e-07
Identities = 26/61 (42%), Positives = 39/61 (63%)
Frame = +3
Query: 321 DELSVIHVAGTKGKGSTSAMCDSILRHHGFRTGFFSSPHLIAVRERIRLDGKIVSEEKFA 500
D+ IHV GT GKGS +A IL G++ G F+SP +I+ +RI L+G+ +S+ + A
Sbjct: 45 DKFPAIHVVGTNGKGSVTAYLQHILSTSGYQVGTFTSPFIISFHDRICLNGQPISDLELA 104
Query: 501 Q 503
Q
Sbjct: 105 Q 105
>UniRef50_A5V1W9 Cluster: FolC bifunctional protein; n=2;
Roseiflexus|Rep: FolC bifunctional protein - Roseiflexus
sp. RS-1
Length = 453
Score = 56.4 bits (130), Expect = 4e-07
Identities = 27/47 (57%), Positives = 38/47 (80%)
Frame = +3
Query: 330 SVIHVAGTKGKGSTSAMCDSILRHHGFRTGFFSSPHLIAVRERIRLD 470
SVI +AGTKGKGST+A+ ++I+R G RTG ++SPHL RERI+++
Sbjct: 48 SVI-IAGTKGKGSTAALLEAIVRAAGLRTGLWTSPHLHTYRERIQVN 93
>UniRef50_A3IEY3 Cluster: FolC; n=1; Bacillus sp. B14905|Rep: FolC -
Bacillus sp. B14905
Length = 416
Score = 56.4 bits (130), Expect = 4e-07
Identities = 24/65 (36%), Positives = 41/65 (63%)
Frame = +3
Query: 327 LSVIHVAGTKGKGSTSAMCDSILRHHGFRTGFFSSPHLIAVRERIRLDGKIVSEEKFAQH 506
L V+H+AGT GKGST ++I + H R G F SP ++ V ++I++DG+ ++E
Sbjct: 41 LHVVHLAGTNGKGSTLTFLEAIAKEHELRVGKFMSPCIVDVHDQIQIDGQPITEADMDAV 100
Query: 507 FHRVY 521
F +++
Sbjct: 101 FRQMH 105
>UniRef50_Q9U738 Cluster: Dihydrofolate synthase/folylpolyglutamate
synthase; n=6; Plasmodium|Rep: Dihydrofolate
synthase/folylpolyglutamate synthase - Plasmodium
falciparum
Length = 522
Score = 56.4 bits (130), Expect = 4e-07
Identities = 26/68 (38%), Positives = 41/68 (60%)
Frame = +3
Query: 321 DELSVIHVAGTKGKGSTSAMCDSILRHHGFRTGFFSSPHLIAVRERIRLDGKIVSEEKFA 500
D+ IH+AGT GKGS + L+ F+ G FSSPH+ ++RERI ++ + +SE++
Sbjct: 93 DKYKTIHIAGTNGKGSVCYKIYTCLKIKKFKVGLFSSPHIFSLRERIIVNDEPISEKELI 152
Query: 501 QHFHRVYN 524
+ V N
Sbjct: 153 HLVNEVLN 160
>UniRef50_A0ECV5 Cluster: Chromosome undetermined scaffold_9, whole
genome shotgun sequence; n=1; Paramecium
tetraurelia|Rep: Chromosome undetermined scaffold_9,
whole genome shotgun sequence - Paramecium tetraurelia
Length = 258
Score = 56.4 bits (130), Expect = 4e-07
Identities = 29/68 (42%), Positives = 42/68 (61%), Gaps = 1/68 (1%)
Frame = +3
Query: 324 ELSVIHVAGTKGKGS-TSAMCDSILRHHGFRTGFFSSPHLIAVRERIRLDGKIVSEEKFA 500
+L IH+AGT GKGS T MC L G F+SPH+ + RERI++D +++SEE
Sbjct: 40 DLQFIHIAGTNGKGSVTLKMCK--LMQSIESCGCFTSPHISSFRERIKVDNQMISEEYVQ 97
Query: 501 QHFHRVYN 524
+H + +N
Sbjct: 98 EHLNDFFN 105
>UniRef50_Q05865 Cluster: Folylpolyglutamate synthase; n=4;
Bacillus|Rep: Folylpolyglutamate synthase - Bacillus
subtilis
Length = 430
Score = 56.4 bits (130), Expect = 4e-07
Identities = 25/58 (43%), Positives = 39/58 (67%)
Frame = +3
Query: 324 ELSVIHVAGTKGKGSTSAMCDSILRHHGFRTGFFSSPHLIAVRERIRLDGKIVSEEKF 497
++ HVAGT GKGST A S+L+ G+ G F+SP++I ERI ++G +S+E++
Sbjct: 40 KIRAFHVAGTNGKGSTVAFIRSMLQEAGYTVGTFTSPYIITFNERISVNGIPISDEEW 97
>UniRef50_Q2ZYL0 Cluster: Folylpolyglutamate synthetase; n=5;
Streptococcus suis|Rep: Folylpolyglutamate synthetase -
Streptococcus suis 89/1591
Length = 418
Score = 56.0 bits (129), Expect = 6e-07
Identities = 31/81 (38%), Positives = 46/81 (56%), Gaps = 4/81 (4%)
Frame = +3
Query: 273 DMERYLFRTGVTLTKLD----ELSVIHVAGTKGKGSTSAMCDSILRHHGFRTGFFSSPHL 440
D+E + R L +LD ++S IH GT GKGST SIL+ + G F+SP +
Sbjct: 17 DLEHGVARVNWILERLDNPQLQVSTIHFVGTNGKGSTLNALQSILQSSDYTVGRFTSPSI 76
Query: 441 IAVRERIRLDGKIVSEEKFAQ 503
I RE+I + +++SEE F +
Sbjct: 77 IDFREQIVFEQEMISEEDFVR 97
>UniRef50_Q0AGX2 Cluster: FolC bifunctional protein; n=1;
Nitrosomonas eutropha C91|Rep: FolC bifunctional protein
- Nitrosomonas eutropha (strain C71)
Length = 428
Score = 56.0 bits (129), Expect = 6e-07
Identities = 25/58 (43%), Positives = 38/58 (65%)
Frame = +3
Query: 318 LDELSVIHVAGTKGKGSTSAMCDSILRHHGFRTGFFSSPHLIAVRERIRLDGKIVSEE 491
+ + VI VAGT GKGS + +SIL +R G ++SPHL+ ERIR+D + +++E
Sbjct: 41 MPKFPVITVAGTNGKGSVCTILESILGRASYRVGCYTSPHLLHYGERIRIDQRAITDE 98
>UniRef50_A7HDB5 Cluster: FolC bifunctional protein; n=2;
Anaeromyxobacter|Rep: FolC bifunctional protein -
Anaeromyxobacter sp. Fw109-5
Length = 403
Score = 56.0 bits (129), Expect = 6e-07
Identities = 24/56 (42%), Positives = 35/56 (62%)
Frame = +3
Query: 333 VIHVAGTKGKGSTSAMCDSILRHHGFRTGFFSSPHLIAVRERIRLDGKIVSEEKFA 500
V+HV GT GKGST AM + L G G ++SPHL+ ERI++ G + +++ A
Sbjct: 39 VLHVGGTNGKGSTCAMAAAALAAAGHEVGLYTSPHLVRFNERIQVRGAAIGDDELA 94
>UniRef50_A7DJF5 Cluster: FolC bifunctional protein; n=1;
Methylobacterium extorquens PA1|Rep: FolC bifunctional
protein - Methylobacterium extorquens PA1
Length = 390
Score = 56.0 bits (129), Expect = 6e-07
Identities = 31/65 (47%), Positives = 38/65 (58%), Gaps = 4/65 (6%)
Frame = +3
Query: 333 VIHVAGTKGKGSTSAMCDSILRHHGFRTGFFSSPHLIAVRERIRL----DGKIVSEEKFA 500
VIHVAGT GKGST A +IL G ++SPHL+ ERIRL G V+E++ A
Sbjct: 43 VIHVAGTNGKGSTIAFMRAILEAGGLAAHVYTSPHLVRFHERIRLGGIGGGHYVAEDRLA 102
Query: 501 QHFHR 515
F R
Sbjct: 103 DAFAR 107
>UniRef50_P73842 Cluster: Folyl-polyglutamate synthetase; n=10;
Cyanobacteria|Rep: Folyl-polyglutamate synthetase -
Synechocystis sp. (strain PCC 6803)
Length = 428
Score = 55.6 bits (128), Expect = 8e-07
Identities = 23/51 (45%), Positives = 33/51 (64%)
Frame = +3
Query: 336 IHVAGTKGKGSTSAMCDSILRHHGFRTGFFSSPHLIAVRERIRLDGKIVSE 488
+HV GT GKGS A S+L G++ G ++SPHLI RER+ LD + + +
Sbjct: 39 VHVGGTNGKGSVCAYLSSVLAEAGYKVGRYTSPHLIDWRERVWLDNRFIDD 89
>UniRef50_Q5VAN8 Cluster: FolC; n=63; Alphaproteobacteria|Rep: FolC
- Rhizobium etli
Length = 450
Score = 55.6 bits (128), Expect = 8e-07
Identities = 34/90 (37%), Positives = 49/90 (54%), Gaps = 5/90 (5%)
Frame = +3
Query: 264 NLEDMERYLFRTGVTLTKLDELSVIHVAGTKGKGSTSAMCDSILRHHGFRTGFFSSPHLI 443
+L+ + R L R G KL V+HVAGT GKGS +A C ++L G+ +SPHL+
Sbjct: 30 SLDRITRLLDRLGNPHRKLPP--VVHVAGTNGKGSVTAFCRALLEAGGYSAHVHTSPHLV 87
Query: 444 AVRERIRLD-----GKIVSEEKFAQHFHRV 518
ER R+ G++V + FA+ RV
Sbjct: 88 NWHERYRIGVAGGRGQLVDDAVFAEAVRRV 117
>UniRef50_A6DD55 Cluster: Folylpolyglutamate synthetase; n=1;
Caminibacter mediatlanticus TB-2|Rep: Folylpolyglutamate
synthetase - Caminibacter mediatlanticus TB-2
Length = 378
Score = 55.6 bits (128), Expect = 8e-07
Identities = 24/63 (38%), Positives = 38/63 (60%)
Frame = +3
Query: 315 KLDELSVIHVAGTKGKGSTSAMCDSILRHHGFRTGFFSSPHLIAVRERIRLDGKIVSEEK 494
K++ VIH+ GT GKGST L G+ G ++SPH++ ERI ++G+ +S+EK
Sbjct: 35 KINIPPVIHIVGTNGKGSTGRFLAYTLLKRGYNVGHYTSPHILKFNERIWINGENISDEK 94
Query: 495 FAQ 503
+
Sbjct: 95 LEE 97
>UniRef50_Q68WJ9 Cluster: Folylpolyglutamate synthase; n=11;
Rickettsieae|Rep: Folylpolyglutamate synthase -
Rickettsia typhi
Length = 433
Score = 55.2 bits (127), Expect = 1e-06
Identities = 26/57 (45%), Positives = 37/57 (64%)
Frame = +3
Query: 333 VIHVAGTKGKGSTSAMCDSILRHHGFRTGFFSSPHLIAVRERIRLDGKIVSEEKFAQ 503
VIH+AGT GKGS+SAM SI G++ ++SPHL+ ERI + G+ +S+ Q
Sbjct: 39 VIHIAGTNGKGSSSAMLKSIFTVAGYKVHCYTSPHLLEFNERIIVAGEKISDNALWQ 95
>UniRef50_Q5FKW4 Cluster: Folylpolyglutamate synthase; n=6;
Lactobacillus|Rep: Folylpolyglutamate synthase -
Lactobacillus acidophilus
Length = 423
Score = 55.2 bits (127), Expect = 1e-06
Identities = 23/57 (40%), Positives = 38/57 (66%)
Frame = +3
Query: 321 DELSVIHVAGTKGKGSTSAMCDSILRHHGFRTGFFSSPHLIAVRERIRLDGKIVSEE 491
+++ IH+ GT GKGSTS ++L+ G +TG F SP++ ERI+LD + +S++
Sbjct: 40 NQVKTIHITGTNGKGSTSYYLSNLLKKAGQKTGLFVSPYVYRFNERIQLDNQDISDQ 96
>UniRef50_Q1JY09 Cluster: FolC bifunctional protein; n=1;
Desulfuromonas acetoxidans DSM 684|Rep: FolC
bifunctional protein - Desulfuromonas acetoxidans DSM
684
Length = 430
Score = 55.2 bits (127), Expect = 1e-06
Identities = 23/52 (44%), Positives = 34/52 (65%)
Frame = +3
Query: 333 VIHVAGTKGKGSTSAMCDSILRHHGFRTGFFSSPHLIAVRERIRLDGKIVSE 488
++HVAGT GKGS A I R G++ G ++SPHL ERIR++G+ + +
Sbjct: 42 IVHVAGTNGKGSVCAFLGRIYRQAGYQVGVYTSPHLHRFNERIRVNGQPIDD 93
>UniRef50_Q1GU94 Cluster: FolC bifunctional protein; n=5;
Sphingomonadales|Rep: FolC bifunctional protein -
Sphingopyxis alaskensis (Sphingomonas alaskensis)
Length = 443
Score = 55.2 bits (127), Expect = 1e-06
Identities = 32/87 (36%), Positives = 42/87 (48%)
Frame = +3
Query: 240 LRTGKRCTNLEDMERYLFRTGVTLTKLDELSVIHVAGTKGKGSTSAMCDSILRHHGFRTG 419
L G+ LE + R G +L V HVAGT GKGST A + + G
Sbjct: 22 LSPGRDILGLERITELCHRLGDPQHRLPP--VFHVAGTNGKGSTCAFLRAAIEAQGLTAH 79
Query: 420 FFSSPHLIAVRERIRLDGKIVSEEKFA 500
+SSPHL+ ERIRL G ++ + A
Sbjct: 80 VYSSPHLVRFNERIRLAGALIDDALLA 106
>UniRef50_Q1AVT2 Cluster: FolC bifunctional protein; n=1;
Rubrobacter xylanophilus DSM 9941|Rep: FolC bifunctional
protein - Rubrobacter xylanophilus (strain DSM 9941 /
NBRC 16129)
Length = 409
Score = 55.2 bits (127), Expect = 1e-06
Identities = 35/102 (34%), Positives = 54/102 (52%), Gaps = 1/102 (0%)
Frame = +3
Query: 198 LQSNKSTIDQIRKDLRTGKRCT-NLEDMERYLFRTGVTLTKLDELSVIHVAGTKGKGSTS 374
L + + + ++ +L KR T LE +E L G + L V+ V GT GKG+T+
Sbjct: 6 LPARRFSFREVAGELDRRKRMTLGLERVEALLEALG---HPEERLRVVQVVGTNGKGTTA 62
Query: 375 AMCDSILRHHGFRTGFFSSPHLIAVRERIRLDGKIVSEEKFA 500
A L G G + SPH+++ ER+ L G+ V+EE+FA
Sbjct: 63 AALALALEELGEPAGLYLSPHVLSYAERVALRGRRVTEEEFA 104
>UniRef50_A4XL37 Cluster: FolC bifunctional protein; n=2;
Clostridiales|Rep: FolC bifunctional protein -
Caldicellulosiruptor saccharolyticus (strain ATCC 43494
/ DSM 8903)
Length = 431
Score = 54.8 bits (126), Expect = 1e-06
Identities = 23/59 (38%), Positives = 39/59 (66%)
Frame = +3
Query: 324 ELSVIHVAGTKGKGSTSAMCDSILRHHGFRTGFFSSPHLIAVRERIRLDGKIVSEEKFA 500
+L ++HVAGT GKGST A + +L G++ G ++SP+L ERI+++ +S ++ A
Sbjct: 40 DLRIVHVAGTNGKGSTCAFINQMLIEAGYKVGLYTSPYLEFFNERIKINNIPISNDELA 98
>UniRef50_A4E6Z7 Cluster: Putative uncharacterized protein; n=1;
Collinsella aerofaciens ATCC 25986|Rep: Putative
uncharacterized protein - Collinsella aerofaciens ATCC
25986
Length = 459
Score = 54.8 bits (126), Expect = 1e-06
Identities = 24/56 (42%), Positives = 37/56 (66%)
Frame = +3
Query: 336 IHVAGTKGKGSTSAMCDSILRHHGFRTGFFSSPHLIAVRERIRLDGKIVSEEKFAQ 503
I VAGT GK ST+ ++L G +T ++SP L+ ER+ +DG++VS+E FA+
Sbjct: 72 IQVAGTNGKTSTTRFSAAVLCGEGLKTALYTSPQLVRYPERMEVDGRVVSDEAFAR 127
>UniRef50_A4BHC7 Cluster: FolC bifunctional folylpolyglutamate
synthase/dihydrofolate synthase; n=1; Reinekea sp.
MED297|Rep: FolC bifunctional folylpolyglutamate
synthase/dihydrofolate synthase - Reinekea sp. MED297
Length = 401
Score = 54.8 bits (126), Expect = 1e-06
Identities = 29/81 (35%), Positives = 47/81 (58%)
Frame = +3
Query: 276 MERYLFRTGVTLTKLDELSVIHVAGTKGKGSTSAMCDSILRHHGFRTGFFSSPHLIAVRE 455
+ER L R L + +V+ VAGT GKG+TSA ++ + G + G ++SPHL E
Sbjct: 26 LER-LKRVATELLQKTPPTVMTVAGTNGKGTTSAAIAALCQSAGAKVGLYTSPHLFRFNE 84
Query: 456 RIRLDGKIVSEEKFAQHFHRV 518
RIR++ + V+++ + F V
Sbjct: 85 RIRINNEPVADQLLVEAFQAV 105
>UniRef50_A1SW71 Cluster: FolC bifunctional protein; n=2;
Psychromonas|Rep: FolC bifunctional protein -
Psychromonas ingrahamii (strain 37)
Length = 428
Score = 54.8 bits (126), Expect = 1e-06
Identities = 25/65 (38%), Positives = 39/65 (60%)
Frame = +3
Query: 324 ELSVIHVAGTKGKGSTSAMCDSILRHHGFRTGFFSSPHLIAVRERIRLDGKIVSEEKFAQ 503
+ VI VAGT GKG+T A + IL GF+ G +SSPH+ ER+R++ + +S++
Sbjct: 48 DAQVITVAGTNGKGTTCAFLEEILLQAGFKVGVYSSPHIQRYTERLRINKQELSDQAHCD 107
Query: 504 HFHRV 518
F +
Sbjct: 108 AFSAI 112
>UniRef50_Q9K8G9 Cluster: Folyl-polyglutamate synthetase; n=1;
Bacillus halodurans|Rep: Folyl-polyglutamate synthetase
- Bacillus halodurans
Length = 430
Score = 54.4 bits (125), Expect = 2e-06
Identities = 24/60 (40%), Positives = 37/60 (61%)
Frame = +3
Query: 324 ELSVIHVAGTKGKGSTSAMCDSILRHHGFRTGFFSSPHLIAVRERIRLDGKIVSEEKFAQ 503
EL+V+H+ GT GKGST + +L G+ G F+SP++ RERI G+ +S E+ +
Sbjct: 39 ELNVVHIGGTNGKGSTVSFMRCMLTEAGYNVGTFTSPYIEHFRERIAYKGEPISSEELVR 98
>UniRef50_Q8D2P3 Cluster: FolC protein; n=1; Wigglesworthia
glossinidia endosymbiont of Glossina brevipalpis|Rep:
FolC protein - Wigglesworthia glossinidia brevipalpis
Length = 428
Score = 54.4 bits (125), Expect = 2e-06
Identities = 28/70 (40%), Positives = 40/70 (57%)
Frame = +3
Query: 285 YLFRTGVTLTKLDELSVIHVAGTKGKGSTSAMCDSILRHHGFRTGFFSSPHLIAVRERIR 464
Y F + L K ++++ V GT GKGST + + + + G +SSPHLI ERIR
Sbjct: 36 YYFAKRLNLLKPAPITIV-VGGTNGKGSTCRFLELMFIYSNIKVGVYSSPHLINYNERIR 94
Query: 465 LDGKIVSEEK 494
L G VS+E+
Sbjct: 95 LHGNEVSDEE 104
>UniRef50_Q88UX8 Cluster: Folylpolyglutamate synthase; n=2;
Lactobacillus|Rep: Folylpolyglutamate synthase -
Lactobacillus plantarum
Length = 444
Score = 54.4 bits (125), Expect = 2e-06
Identities = 30/81 (37%), Positives = 43/81 (53%)
Frame = +3
Query: 252 KRCTNLEDMERYLFRTGVTLTKLDELSVIHVAGTKGKGSTSAMCDSILRHHGFRTGFFSS 431
K+ L M ++L G K+ + IHVAGT GKGST A + G G F+S
Sbjct: 19 KKAPTLSRMRQFLHELGDPQLKV---AGIHVAGTNGKGSTVANLRELFMADGLTVGTFTS 75
Query: 432 PHLIAVRERIRLDGKIVSEEK 494
P ++ ERI +DG +S+E+
Sbjct: 76 PFIVRFNERISVDGTPISDEE 96
>UniRef50_Q4AKU0 Cluster: Folylpolyglutamate synthetase; n=1;
Chlorobium phaeobacteroides BS1|Rep: Folylpolyglutamate
synthetase - Chlorobium phaeobacteroides BS1
Length = 436
Score = 54.4 bits (125), Expect = 2e-06
Identities = 24/58 (41%), Positives = 37/58 (63%)
Frame = +3
Query: 333 VIHVAGTKGKGSTSAMCDSILRHHGFRTGFFSSPHLIAVRERIRLDGKIVSEEKFAQH 506
V+H+AGT GKG+ + SI GF TG ++SPHL++ ERI ++G + E + A +
Sbjct: 55 VVHIAGTNGKGTVAYAVASIFSSAGFTTGLYTSPHLVSFTERICVNGCRIPEPQVAAY 112
>UniRef50_Q0ATK3 Cluster: FolC bifunctional protein; n=1; Maricaulis
maris MCS10|Rep: FolC bifunctional protein - Maricaulis
maris (strain MCS10)
Length = 397
Score = 54.4 bits (125), Expect = 2e-06
Identities = 27/60 (45%), Positives = 34/60 (56%)
Frame = +3
Query: 336 IHVAGTKGKGSTSAMCDSILRHHGFRTGFFSSPHLIAVRERIRLDGKIVSEEKFAQHFHR 515
IHVAGT GKGST A + R G R ++SPHL+ ERI LD + V + + F R
Sbjct: 5 IHVAGTNGKGSTCAYLAEMARAKGERVHIYTSPHLVNFNERILLDSRPVDDRTLIEAFAR 64
>UniRef50_Q0AQK7 Cluster: FolC bifunctional protein; n=1; Maricaulis
maris MCS10|Rep: FolC bifunctional protein - Maricaulis
maris (strain MCS10)
Length = 439
Score = 54.4 bits (125), Expect = 2e-06
Identities = 26/67 (38%), Positives = 41/67 (61%)
Frame = +3
Query: 294 RTGVTLTKLDELSVIHVAGTKGKGSTSAMCDSILRHHGFRTGFFSSPHLIAVRERIRLDG 473
R G+ L + SV+ +AG+ GKGS + M + + G RTG F+SPHL A ER L G
Sbjct: 26 RLGLDLPAIGRRSVV-IAGSNGKGSVARMLGGLFQAAGERTGLFTSPHLQAFNERFELAG 84
Query: 474 KIVSEEK 494
+++++ +
Sbjct: 85 EMIADNR 91
>UniRef50_Q04MP6 Cluster: Folylpolyglutamate synthase; n=14;
Streptococcus|Rep: Folylpolyglutamate synthase -
Streptococcus pneumoniae serotype 2 (strain D39 / NCTC
7466)
Length = 418
Score = 54.4 bits (125), Expect = 2e-06
Identities = 21/55 (38%), Positives = 36/55 (65%)
Frame = +3
Query: 333 VIHVAGTKGKGSTSAMCDSILRHHGFRTGFFSSPHLIAVRERIRLDGKIVSEEKF 497
+IHV GT GKGST A + HG + F+SPH++++ +RI ++G+ +++ F
Sbjct: 41 IIHVTGTNGKGSTIAFMRELFMGHGKKVATFTSPHIVSINDRICINGQPIADADF 95
>UniRef50_A5IBI5 Cluster: FolC bifunctional protein; n=4; Legionella
pneumophila|Rep: FolC bifunctional protein - Legionella
pneumophila (strain Corby)
Length = 428
Score = 54.4 bits (125), Expect = 2e-06
Identities = 25/59 (42%), Positives = 36/59 (61%)
Frame = +3
Query: 333 VIHVAGTKGKGSTSAMCDSILRHHGFRTGFFSSPHLIAVRERIRLDGKIVSEEKFAQHF 509
VI VAGT GKGST ++I GFR G ++SPHL+ ERIR++ + ++ + F
Sbjct: 48 VITVAGTNGKGSTVTALETIYHQSGFRVGTYTSPHLLVFNERIRINLTPIQDKDLCKAF 106
>UniRef50_Q00X21 Cluster: Dihydrofolate synthetase
/folylpolyglutamate synthetase; n=2; Ostreococcus|Rep:
Dihydrofolate synthetase /folylpolyglutamate synthetase
- Ostreococcus tauri
Length = 483
Score = 54.4 bits (125), Expect = 2e-06
Identities = 25/54 (46%), Positives = 35/54 (64%)
Frame = +3
Query: 330 SVIHVAGTKGKGSTSAMCDSILRHHGFRTGFFSSPHLIAVRERIRLDGKIVSEE 491
+ +HV+GTKGKG+T ++ S+LR G R G + SPH+ V ERIR + S E
Sbjct: 69 TTVHVSGTKGKGTTLSVLASVLRSAGKRVGTYKSPHVYTVAERIRSSDEDASTE 122
>UniRef50_Q9RXH3 Cluster: Folyl-polyglutamate synthetase; n=2;
Deinococcus|Rep: Folyl-polyglutamate synthetase -
Deinococcus radiodurans
Length = 416
Score = 54.0 bits (124), Expect = 2e-06
Identities = 28/60 (46%), Positives = 36/60 (60%)
Frame = +3
Query: 324 ELSVIHVAGTKGKGSTSAMCDSILRHHGFRTGFFSSPHLIAVRERIRLDGKIVSEEKFAQ 503
+ I V GT GKGST AM ++ L G R G F+SPHL A ERIR+ G+ + + AQ
Sbjct: 60 KFQTIRVVGTNGKGSTCAMLEAGLLAAGVRAGRFTSPHLHAYEERIRVGGENLDPARTAQ 119
>UniRef50_Q92BG3 Cluster: FolC protein; n=11; Listeria|Rep: FolC
protein - Listeria innocua
Length = 429
Score = 54.0 bits (124), Expect = 2e-06
Identities = 36/107 (33%), Positives = 56/107 (52%)
Frame = +3
Query: 198 LQSNKSTIDQIRKDLRTGKRCTNLEDMERYLFRTGVTLTKLDELSVIHVAGTKGKGSTSA 377
L+S + +D I LR G + L ME Y+ K ++ +H+AGT GKGST
Sbjct: 3 LKSYQEALDWIHGTLRLGIK-PGLARME-YIMEKLNHPEKANKW--VHIAGTNGKGSTLT 58
Query: 378 MCDSILRHHGFRTGFFSSPHLIAVRERIRLDGKIVSEEKFAQHFHRV 518
S L G++TG F+SP++ ERI ++G VS++ +R+
Sbjct: 59 FIRSSLEEAGYKTGTFTSPYIETFNERISVNGIPVSDQMIVDLANRI 105
>UniRef50_Q82ZW9 Cluster: FolC family protein; n=7; Firmicutes|Rep:
FolC family protein - Enterococcus faecalis
(Streptococcus faecalis)
Length = 440
Score = 54.0 bits (124), Expect = 2e-06
Identities = 27/80 (33%), Positives = 45/80 (56%), Gaps = 4/80 (5%)
Frame = +3
Query: 288 LFRTGVTLTKLD----ELSVIHVAGTKGKGSTSAMCDSILRHHGFRTGFFSSPHLIAVRE 455
L R L K+D ++ IH+AGT GKGST +L G + G F+SP++ + E
Sbjct: 24 LDRINALLEKIDHPENKVPTIHIAGTNGKGSTVTYLRCLLEEMGLKVGTFTSPYIESFNE 83
Query: 456 RIRLDGKIVSEEKFAQHFHR 515
RI ++G+ +S+E+ + +
Sbjct: 84 RIAINGQPISDEQLITYVEK 103
>UniRef50_Q21IZ3 Cluster: FolC bifunctional protein; n=1;
Saccharophagus degradans 2-40|Rep: FolC bifunctional
protein - Saccharophagus degradans (strain 2-40 / ATCC
43961 / DSM 17024)
Length = 427
Score = 54.0 bits (124), Expect = 2e-06
Identities = 26/63 (41%), Positives = 38/63 (60%)
Frame = +3
Query: 330 SVIHVAGTKGKGSTSAMCDSILRHHGFRTGFFSSPHLIAVRERIRLDGKIVSEEKFAQHF 509
+VI VAGT GKGS C+++L G G F+SPH++ ERIR+DG +S+ F
Sbjct: 42 TVITVAGTNGKGSFVRSCEAMLGASGMHFGSFTSPHILEYNERIRVDGVDLSDGLICDVF 101
Query: 510 HRV 518
++
Sbjct: 102 AQI 104
>UniRef50_Q6CHD4 Cluster: Similar to sp|Q12676 Saccharomyces
cerevisiae YMR113w FOL3 dihydrofolate synthetase; n=1;
Yarrowia lipolytica|Rep: Similar to sp|Q12676
Saccharomyces cerevisiae YMR113w FOL3 dihydrofolate
synthetase - Yarrowia lipolytica (Candida lipolytica)
Length = 406
Score = 54.0 bits (124), Expect = 2e-06
Identities = 26/59 (44%), Positives = 34/59 (57%)
Frame = +3
Query: 321 DELSVIHVAGTKGKGSTSAMCDSILRHHGFRTGFFSSPHLIAVRERIRLDGKIVSEEKF 497
+ +HVAGT GKGS A S+L +TG F+SPHL V + I +DGK V + F
Sbjct: 21 NRFKAVHVAGTNGKGSICAYISSVLTVSHIKTGRFTSPHLAYVWDCITIDGKAVEKSDF 79
>UniRef50_Q8K9X3 Cluster: Bifunctional protein folC [Includes:
Folylpolyglutamate synthase (EC 6.3.2.17)
(Folylpoly-gamma-glutamate synthetase) (FPGS)
(Tetrahydrofolate synthase)
(Tetrahydrofolylpolyglutamate synthase); Dihydrofolate
synthase (EC 6.3.2.12)]; n=1; Buchnera aphidicola
(Schizaphis graminum)|Rep: Bifunctional protein folC
[Includes: Folylpolyglutamate synthase (EC 6.3.2.17)
(Folylpoly-gamma-glutamate synthetase) (FPGS)
(Tetrahydrofolate synthase)
(Tetrahydrofolylpolyglutamate synthase); Dihydrofolate
synthase (EC 6.3.2.12)] - Buchnera aphidicola subsp.
Schizaphis graminum
Length = 418
Score = 54.0 bits (124), Expect = 2e-06
Identities = 23/50 (46%), Positives = 35/50 (70%)
Frame = +3
Query: 342 VAGTKGKGSTSAMCDSILRHHGFRTGFFSSPHLIAVRERIRLDGKIVSEE 491
V GT GKG+T AM + +L G++ G ++SPHLI ERI+++G +SE+
Sbjct: 48 VGGTNGKGTTCAMLEKLLLDSGYQVGLYTSPHLINYSERIKVNGLYLSEK 97
>UniRef50_UPI00015BCA34 Cluster: UPI00015BCA34 related cluster; n=1;
unknown|Rep: UPI00015BCA34 UniRef100 entry - unknown
Length = 412
Score = 53.6 bits (123), Expect = 3e-06
Identities = 26/55 (47%), Positives = 36/55 (65%)
Frame = +3
Query: 330 SVIHVAGTKGKGSTSAMCDSILRHHGFRTGFFSSPHLIAVRERIRLDGKIVSEEK 494
SVI V GT GKGST A + +L HG TG+F SPHL+ ER+R++ + +E+
Sbjct: 37 SVI-VGGTNGKGSTCAFLNYLLIEHGLNTGWFVSPHLVRENERLRVNNIHIKDEE 90
>UniRef50_Q9CN13 Cluster: FolC; n=7; Pasteurellaceae|Rep: FolC -
Pasteurella multocida
Length = 442
Score = 53.6 bits (123), Expect = 3e-06
Identities = 23/59 (38%), Positives = 36/59 (61%)
Frame = +3
Query: 333 VIHVAGTKGKGSTSAMCDSILRHHGFRTGFFSSPHLIAVRERIRLDGKIVSEEKFAQHF 509
VI V GT GKG+T + +++L G+R G +SSPHL+ ER+R+ + + +E F
Sbjct: 52 VITVGGTNGKGTTCRLLETVLLKAGYRVGVYSSPHLLRYNERVRIQDQELPDEAHTASF 110
>UniRef50_Q15VG0 Cluster: FolC bifunctional protein; n=1;
Pseudoalteromonas atlantica T6c|Rep: FolC bifunctional
protein - Pseudoalteromonas atlantica (strain T6c /
BAA-1087)
Length = 426
Score = 53.6 bits (123), Expect = 3e-06
Identities = 27/63 (42%), Positives = 37/63 (58%)
Frame = +3
Query: 330 SVIHVAGTKGKGSTSAMCDSILRHHGFRTGFFSSPHLIAVRERIRLDGKIVSEEKFAQHF 509
+V+ VAGT GKG+T A + G R G +SSPHLI ER+R++G SE+ + F
Sbjct: 54 TVVTVAGTNGKGTTCAFLEQACLAAGKRVGVYSSPHLIQYTERVRINGIDGSEQAHCRAF 113
Query: 510 HRV 518
V
Sbjct: 114 QAV 116
>UniRef50_Q0GL77 Cluster: Folylpolyglutamate synthase; n=3;
Lactobacillus reuteri|Rep: Folylpolyglutamate synthase -
Lactobacillus reuteri
Length = 437
Score = 53.6 bits (123), Expect = 3e-06
Identities = 31/80 (38%), Positives = 41/80 (51%)
Frame = +3
Query: 252 KRCTNLEDMERYLFRTGVTLTKLDELSVIHVAGTKGKGSTSAMCDSILRHHGFRTGFFSS 431
K+ L M+R+L G + L IHV GT GKGST AM S L G G F+S
Sbjct: 19 KKIPTLTRMKRFLAELG---NPQEGLKYIHVTGTNGKGSTVAMMRSALLESGLTVGSFTS 75
Query: 432 PHLIAVRERIRLDGKIVSEE 491
P + ERI +G +S++
Sbjct: 76 PFITRFNERIEYNGIPISDD 95
>UniRef50_A3S1I7 Cluster: Folylpolyglutamate synthase; n=1;
Prochlorococcus marinus str. MIT 9211|Rep:
Folylpolyglutamate synthase - Prochlorococcus marinus
str. MIT 9211
Length = 413
Score = 53.6 bits (123), Expect = 3e-06
Identities = 24/59 (40%), Positives = 38/59 (64%)
Frame = +3
Query: 321 DELSVIHVAGTKGKGSTSAMCDSILRHHGFRTGFFSSPHLIAVRERIRLDGKIVSEEKF 497
+E+ I V GT GKGS + +S L+ + G +SPHL++ RERIR++G+ +S + F
Sbjct: 43 NEIPAIQVIGTNGKGSIVSFLESCLKEARIKIGCSTSPHLVSWRERIRINGQEISSQDF 101
>UniRef50_Q6KZL1 Cluster: Folylpolyglutamate synthase/dihydrofolate
synthase; n=3; Thermoplasmatales|Rep: Folylpolyglutamate
synthase/dihydrofolate synthase - Picrophilus torridus
Length = 435
Score = 53.6 bits (123), Expect = 3e-06
Identities = 25/57 (43%), Positives = 38/57 (66%)
Frame = +3
Query: 321 DELSVIHVAGTKGKGSTSAMCDSILRHHGFRTGFFSSPHLIAVRERIRLDGKIVSEE 491
D+ IH+AGT GKGS S+ +ILR + TG ++SPHLI ERI + +++S++
Sbjct: 35 DKYKKIHIAGTNGKGSISSYIYNILRQR-YNTGLYTSPHLIKFNERIIFNKEMISDD 90
>UniRef50_Q83D50 Cluster: FolC bifunctional protein; n=4; Coxiella
burnetii|Rep: FolC bifunctional protein - Coxiella
burnetii
Length = 416
Score = 53.2 bits (122), Expect = 4e-06
Identities = 24/59 (40%), Positives = 37/59 (62%)
Frame = +3
Query: 333 VIHVAGTKGKGSTSAMCDSILRHHGFRTGFFSSPHLIAVRERIRLDGKIVSEEKFAQHF 509
V+ VAGT GKGS +SI G++ ++SPHL+ ER+RL+G+ ++E F + F
Sbjct: 39 VVTVAGTNGKGSVVKSLESIYLAAGYKVAAYTSPHLLQFNERLRLNGEPATDELFIEAF 97
>UniRef50_Q2G8T0 Cluster: FolC bifunctional protein; n=3;
Sphingomonadales|Rep: FolC bifunctional protein -
Novosphingobium aromaticivorans (strain DSM 12444)
Length = 435
Score = 53.2 bits (122), Expect = 4e-06
Identities = 26/56 (46%), Positives = 31/56 (55%)
Frame = +3
Query: 333 VIHVAGTKGKGSTSAMCDSILRHHGFRTGFFSSPHLIAVRERIRLDGKIVSEEKFA 500
V HVAGT GKGST IL G + PHL+ ERIRL GK++ +E A
Sbjct: 51 VFHVAGTNGKGSTCTYLRYILEAEGLTVHSATKPHLVRYNERIRLAGKLIEDELLA 106
>UniRef50_Q11UV3 Cluster: Tetrahydrofolylpolyglutamate synthase;
n=1; Cytophaga hutchinsonii ATCC 33406|Rep:
Tetrahydrofolylpolyglutamate synthase - Cytophaga
hutchinsonii (strain ATCC 33406 / NCIMB 9469)
Length = 429
Score = 53.2 bits (122), Expect = 4e-06
Identities = 22/46 (47%), Positives = 34/46 (73%)
Frame = +3
Query: 336 IHVAGTKGKGSTSAMCDSILRHHGFRTGFFSSPHLIAVRERIRLDG 473
IHVAGT GKGS+S++ ++L+ G+ G ++SPH+ ERIR++G
Sbjct: 49 IHVAGTNGKGSSSSILAAVLQSAGYTVGLYTSPHIHDFTERIRING 94
>UniRef50_Q0EXD2 Cluster: Folylpolyglutamate synthetase; n=1;
Mariprofundus ferrooxydans PV-1|Rep: Folylpolyglutamate
synthetase - Mariprofundus ferrooxydans PV-1
Length = 362
Score = 53.2 bits (122), Expect = 4e-06
Identities = 23/51 (45%), Positives = 34/51 (66%)
Frame = +3
Query: 336 IHVAGTKGKGSTSAMCDSILRHHGFRTGFFSSPHLIAVRERIRLDGKIVSE 488
I +AGT GKGST+ M + L+ G G ++SPH++ ERIR+ G+ VS+
Sbjct: 33 IRIAGTNGKGSTAFMLAAALQSAGLTVGLYTSPHILRFNERIRIQGEPVSD 83
>UniRef50_A5EVX7 Cluster: Folylpolyglutamate synthase; n=1;
Dichelobacter nodosus VCS1703A|Rep: Folylpolyglutamate
synthase - Dichelobacter nodosus (strain VCS1703A)
Length = 422
Score = 53.2 bits (122), Expect = 4e-06
Identities = 26/62 (41%), Positives = 35/62 (56%)
Frame = +3
Query: 333 VIHVAGTKGKGSTSAMCDSILRHHGFRTGFFSSPHLIAVRERIRLDGKIVSEEKFAQHFH 512
+I VAGT GKGS A ++I HG F+SPH+I RERIR + +V E + F
Sbjct: 48 IITVAGTNGKGSCVAWVEAICLAHGISVASFTSPHVIDYRERIRFNDHMVRETELCAAFE 107
Query: 513 RV 518
+
Sbjct: 108 AI 109
>UniRef50_Q83G53 Cluster: Folylpolyglutamate synthase; n=2;
Tropheryma whipplei|Rep: Folylpolyglutamate synthase -
Tropheryma whipplei (strain Twist) (Whipple's bacillus)
Length = 461
Score = 52.8 bits (121), Expect = 5e-06
Identities = 25/59 (42%), Positives = 34/59 (57%)
Frame = +3
Query: 333 VIHVAGTKGKGSTSAMCDSILRHHGFRTGFFSSPHLIAVRERIRLDGKIVSEEKFAQHF 509
VIH+ GT GK + S M IL G R G F+SPH+ A+ ERI++D V +H+
Sbjct: 40 VIHITGTNGKTTVSRMIACILTSLGLRVGLFTSPHITALEERIQIDMNPVQGHILEKHW 98
>UniRef50_A0LA36 Cluster: FolC bifunctional protein; n=2; cellular
organisms|Rep: FolC bifunctional protein - Magnetococcus
sp. (strain MC-1)
Length = 426
Score = 52.8 bits (121), Expect = 5e-06
Identities = 24/52 (46%), Positives = 33/52 (63%)
Frame = +3
Query: 333 VIHVAGTKGKGSTSAMCDSILRHHGFRTGFFSSPHLIAVRERIRLDGKIVSE 488
V+HVAGT GKGS A +ILR G ++SPHL+ + ERI+ +G V +
Sbjct: 47 VVHVAGTNGKGSVIAFFGAILRQAGRSVAAYTSPHLVTIHERIQYNGVPVED 98
>UniRef50_A6R127 Cluster: Putative uncharacterized protein; n=1;
Ajellomyces capsulatus NAm1|Rep: Putative
uncharacterized protein - Ajellomyces capsulatus NAm1
Length = 885
Score = 52.8 bits (121), Expect = 5e-06
Identities = 27/61 (44%), Positives = 35/61 (57%)
Frame = +3
Query: 336 IHVAGTKGKGSTSAMCDSILRHHGFRTGFFSSPHLIAVRERIRLDGKIVSEEKFAQHFHR 515
IH+AGT GKGS + ++L G R G F+SPHLI + I +D +V E F Q H
Sbjct: 476 IHIAGTNGKGSITGYLSALLTAAGVRCGSFTSPHLIDRWDCITIDNCVVHEPLFRQIEHN 535
Query: 516 V 518
V
Sbjct: 536 V 536
>UniRef50_UPI0000DAE3B7 Cluster: hypothetical protein
Rgryl_01000180; n=1; Rickettsiella grylli|Rep:
hypothetical protein Rgryl_01000180 - Rickettsiella
grylli
Length = 430
Score = 52.4 bits (120), Expect = 7e-06
Identities = 24/62 (38%), Positives = 37/62 (59%)
Frame = +3
Query: 333 VIHVAGTKGKGSTSAMCDSILRHHGFRTGFFSSPHLIAVRERIRLDGKIVSEEKFAQHFH 512
++ VAGT GKGS + +IL G+R G ++SPHL ERIR+ + +S++ F
Sbjct: 53 IVTVAGTNGKGSNVGLLAAILSVAGYRVGTYTSPHLRHYHERIRVGSQCISDQDLCHAFF 112
Query: 513 RV 518
+V
Sbjct: 113 QV 114
>UniRef50_Q7TU62 Cluster: Putuative bifunctional
Dihydrofolate/Folylpolyglutamate synthase; n=5;
Prochlorococcus marinus|Rep: Putuative bifunctional
Dihydrofolate/Folylpolyglutamate synthase -
Prochlorococcus marinus subsp. pastoris (strain CCMP
1378 / MED4)
Length = 410
Score = 52.4 bits (120), Expect = 7e-06
Identities = 30/89 (33%), Positives = 51/89 (57%), Gaps = 4/89 (4%)
Frame = +3
Query: 270 EDMERYLFRTGVTLTKLDE----LSVIHVAGTKGKGSTSAMCDSILRHHGFRTGFFSSPH 437
E+++ L R L LD+ + I + GT GKGS +A ++IL G +SPH
Sbjct: 19 ENIQLGLSRIKNALRDLDDPCKNIPAIQIVGTNGKGSITAFIENILYADKKNIGVTTSPH 78
Query: 438 LIAVRERIRLDGKIVSEEKFAQHFHRVYN 524
L+ + ERIR++ + +S+E+F + F ++ N
Sbjct: 79 LLDICERIRVNKEKISKEEFERLFKKIKN 107
>UniRef50_Q5WEQ5 Cluster: Folylpolyglutamate synthase; n=1; Bacillus
clausii KSM-K16|Rep: Folylpolyglutamate synthase -
Bacillus clausii (strain KSM-K16)
Length = 436
Score = 52.4 bits (120), Expect = 7e-06
Identities = 26/64 (40%), Positives = 37/64 (57%)
Frame = +3
Query: 327 LSVIHVAGTKGKGSTSAMCDSILRHHGFRTGFFSSPHLIAVRERIRLDGKIVSEEKFAQH 506
L+ +HVAGT GKGST + IL GF G F+SP++ ERI ++G +S+ Q
Sbjct: 42 LTAVHVAGTNGKGSTVSFLRHILTAGGFSVGTFTSPYIEQFSERISVNGVPISDRDLLQA 101
Query: 507 FHRV 518
R+
Sbjct: 102 AQRL 105
>UniRef50_O26070 Cluster: Folylpolyglutamate synthase; n=4;
Helicobacter|Rep: Folylpolyglutamate synthase -
Helicobacter pylori (Campylobacter pylori)
Length = 394
Score = 52.4 bits (120), Expect = 7e-06
Identities = 24/55 (43%), Positives = 31/55 (56%)
Frame = +3
Query: 324 ELSVIHVAGTKGKGSTSAMCDSILRHHGFRTGFFSSPHLIAVRERIRLDGKIVSE 488
+ VIHV GT GKGST +L F+ F+SPH+ RER L+G +V E
Sbjct: 46 QAKVIHVVGTNGKGSTGRFLTLLLADQNFKVLHFTSPHVFEFRERFFLNGSVVGE 100
>UniRef50_Q41DX5 Cluster: Folylpolyglutamate synthetase; n=1;
Exiguobacterium sibiricum 255-15|Rep: Folylpolyglutamate
synthetase - Exiguobacterium sibiricum 255-15
Length = 416
Score = 52.4 bits (120), Expect = 7e-06
Identities = 26/56 (46%), Positives = 34/56 (60%)
Frame = +3
Query: 321 DELSVIHVAGTKGKGSTSAMCDSILRHHGFRTGFFSSPHLIAVRERIRLDGKIVSE 488
D + IHVAGT GKGST A + G + G F+SP++I ERI L+G +SE
Sbjct: 38 DAIPTIHVAGTNGKGSTVAFLREMGVAEGLQVGTFTSPYIIQFEERIMLNGVPISE 93
>UniRef50_Q12676 Cluster: Folylpolyglutamate synthase; n=5;
Saccharomycetales|Rep: Folylpolyglutamate synthase -
Saccharomyces cerevisiae (Baker's yeast)
Length = 427
Score = 52.4 bits (120), Expect = 7e-06
Identities = 21/59 (35%), Positives = 37/59 (62%)
Frame = +3
Query: 321 DELSVIHVAGTKGKGSTSAMCDSILRHHGFRTGFFSSPHLIAVRERIRLDGKIVSEEKF 497
+ L V+H+AGT GKGS S+L+ ++ G F++PHL+ V + I ++ K + E++
Sbjct: 22 NSLRVLHIAGTNGKGSVCTYLSSVLQQKSYQIGKFTTPHLVHVTDSITINNKPIPLERY 80
>UniRef50_A7C245 Cluster: Folylpolyglutamate synthase/dihydrofolate
synthase; n=1; Beggiatoa sp. PS|Rep: Folylpolyglutamate
synthase/dihydrofolate synthase - Beggiatoa sp. PS
Length = 441
Score = 52.0 bits (119), Expect = 1e-05
Identities = 26/62 (41%), Positives = 35/62 (56%)
Frame = +3
Query: 333 VIHVAGTKGKGSTSAMCDSILRHHGFRTGFFSSPHLIAVRERIRLDGKIVSEEKFAQHFH 512
+I VAGT GKGS+ + DSIL G+ G F SPHL+ ERI + G S+ + F
Sbjct: 44 IITVAGTNGKGSSIILLDSILSTAGYHVGRFMSPHLLRYNERICVGGVEASDVQICHTFE 103
Query: 513 RV 518
+
Sbjct: 104 LI 105
>UniRef50_A1AXP8 Cluster: FolC bifunctional protein; n=3;
Bacteria|Rep: FolC bifunctional protein - Ruthia
magnifica subsp. Calyptogena magnifica
Length = 404
Score = 52.0 bits (119), Expect = 1e-05
Identities = 23/62 (37%), Positives = 37/62 (59%)
Frame = +3
Query: 333 VIHVAGTKGKGSTSAMCDSILRHHGFRTGFFSSPHLIAVRERIRLDGKIVSEEKFAQHFH 512
VI VAGT GKGST+A + I + F+ FSSPH++ ER ++ ++E+ F+
Sbjct: 45 VITVAGTNGKGSTAAFINGIYQQSNFKVAKFSSPHILKYNERFVINDAQATDEQICSAFN 104
Query: 513 RV 518
++
Sbjct: 105 KI 106
>UniRef50_Q9HS44 Cluster: Dihydropteroate synthase; n=4;
Halobacteriaceae|Rep: Dihydropteroate synthase -
Halobacterium salinarium (Halobacterium halobium)
Length = 815
Score = 52.0 bits (119), Expect = 1e-05
Identities = 22/51 (43%), Positives = 35/51 (68%)
Frame = +3
Query: 336 IHVAGTKGKGSTSAMCDSILRHHGFRTGFFSSPHLIAVRERIRLDGKIVSE 488
+ +AG+ GKGST+ +SILR G G ++SPH VRER+ ++G+ +S+
Sbjct: 43 VQIAGSNGKGSTARFTESILRAAGLDVGLYTSPHFDDVRERVTVNGRRMSK 93
>UniRef50_Q8UJA7 Cluster: Folylpolyglutamate synthase; n=2;
Agrobacterium tumefaciens str. C58|Rep:
Folylpolyglutamate synthase - Agrobacterium tumefaciens
(strain C58 / ATCC 33970)
Length = 459
Score = 51.6 bits (118), Expect = 1e-05
Identities = 32/90 (35%), Positives = 45/90 (50%), Gaps = 5/90 (5%)
Frame = +3
Query: 264 NLEDMERYLFRTGVTLTKLDELSVIHVAGTKGKGSTSAMCDSILRHHGFRTGFFSSPHLI 443
+L+ + R L + G ++ VIHVAGT GKGS SA C ++L G + PHL+
Sbjct: 39 SLDRISRLLEKLGNPQNRMPP--VIHVAGTNGKGSVSAFCRALLEAAGLPVHVHTKPHLV 96
Query: 444 AVRERIRLD-----GKIVSEEKFAQHFHRV 518
ER RL G+ V + FA R+
Sbjct: 97 NWHERYRLGVAGERGRFVEDAVFADALRRI 126
>UniRef50_Q5KWL4 Cluster: Folyl-polyglutamate synthetase; n=16;
Bacillaceae|Rep: Folyl-polyglutamate synthetase -
Geobacillus kaustophilus
Length = 449
Score = 51.6 bits (118), Expect = 1e-05
Identities = 22/56 (39%), Positives = 36/56 (64%)
Frame = +3
Query: 336 IHVAGTKGKGSTSAMCDSILRHHGFRTGFFSSPHLIAVRERIRLDGKIVSEEKFAQ 503
+H+ GT GKGST A SIL+ G+ G F+SP++ ERI ++G+ + +E+ +
Sbjct: 44 VHIGGTNGKGSTVAYLRSILQAAGYSVGTFTSPYVEQFNERISINGQPIRDEEIVE 99
>UniRef50_Q2SJC8 Cluster: Folylpolyglutamate synthase; n=1; Hahella
chejuensis KCTC 2396|Rep: Folylpolyglutamate synthase -
Hahella chejuensis (strain KCTC 2396)
Length = 430
Score = 51.6 bits (118), Expect = 1e-05
Identities = 24/63 (38%), Positives = 38/63 (60%)
Frame = +3
Query: 330 SVIHVAGTKGKGSTSAMCDSILRHHGFRTGFFSSPHLIAVRERIRLDGKIVSEEKFAQHF 509
+V+ +AGT GKGST A +++ G G ++SPH++ ER+R++G VS+E F
Sbjct: 44 TVVTIAGTNGKGSTLAAVEALALAAGKTVGAYTSPHILRFNERVRINGVDVSDEALEAAF 103
Query: 510 HRV 518
V
Sbjct: 104 AAV 106
>UniRef50_Q1YT82 Cluster: Folylpolyglutamate synthetase; n=2;
Proteobacteria|Rep: Folylpolyglutamate synthetase -
gamma proteobacterium HTCC2207
Length = 443
Score = 51.6 bits (118), Expect = 1e-05
Identities = 23/63 (36%), Positives = 32/63 (50%)
Frame = +3
Query: 330 SVIHVAGTKGKGSTSAMCDSILRHHGFRTGFFSSPHLIAVRERIRLDGKIVSEEKFAQHF 509
+ I VAGT GKGS A ++ HG+R G F+SPH + ERI + G + F
Sbjct: 50 TAITVAGTNGKGSCLASMQAVAHAHGYRVGLFTSPHFLHYNERIAIQGLPAQDRVIVDAF 109
Query: 510 HRV 518
+
Sbjct: 110 DEI 112
>UniRef50_Q1GBX7 Cluster: Folylpolyglutamate synthase; n=2;
Lactobacillus delbrueckii subsp. bulgaricus|Rep:
Folylpolyglutamate synthase - Lactobacillus delbrueckii
subsp. bulgaricus (strain ATCC 11842 / DSM20081)
Length = 445
Score = 51.6 bits (118), Expect = 1e-05
Identities = 22/60 (36%), Positives = 36/60 (60%)
Frame = +3
Query: 324 ELSVIHVAGTKGKGSTSAMCDSILRHHGFRTGFFSSPHLIAVRERIRLDGKIVSEEKFAQ 503
+ +IH+ GT GKGST+ M +IL+ G R G F+SP++ + I++D K + F +
Sbjct: 39 KFKIIHICGTNGKGSTAMMITAILKQMGHRVGLFTSPYIGEIYNGIQIDFKNIPSRIFEE 98
>UniRef50_Q89AT2 Cluster: Bifunctional protein folC [Includes:
Folylpolyglutamate synthase (EC 6.3.2.17)
(Folylpoly-gamma-glutamate synthetase) (FPGS)
(Tetrahydrofolate synthase)
(Tetrahydrofolylpolyglutamate synthase); Dihydrofolate
synthase (EC 6.3.2.12)]; n=2; Buchnera aphidicola|Rep:
Bifunctional protein folC [Includes: Folylpolyglutamate
synthase (EC 6.3.2.17) (Folylpoly-gamma-glutamate
synthetase) (FPGS) (Tetrahydrofolate synthase)
(Tetrahydrofolylpolyglutamate synthase); Dihydrofolate
synthase (EC 6.3.2.12)] - Buchnera aphidicola subsp.
Baizongia pistaciae
Length = 426
Score = 51.6 bits (118), Expect = 1e-05
Identities = 21/47 (44%), Positives = 33/47 (70%)
Frame = +3
Query: 333 VIHVAGTKGKGSTSAMCDSILRHHGFRTGFFSSPHLIAVRERIRLDG 473
V V GT GKGST + +++L + G+R G ++SPHL+ ER+R++G
Sbjct: 50 VFIVGGTNGKGSTCHVLENLLLNSGYRVGLYTSPHLMRYTERVRING 96
>UniRef50_Q2GD55 Cluster: Folylpolyglutamate synthase; n=1;
Neorickettsia sennetsu str. Miyayama|Rep:
Folylpolyglutamate synthase - Neorickettsia sennetsu
(strain Miyayama)
Length = 442
Score = 51.2 bits (117), Expect = 2e-05
Identities = 25/53 (47%), Positives = 34/53 (64%)
Frame = +3
Query: 333 VIHVAGTKGKGSTSAMCDSILRHHGFRTGFFSSPHLIAVRERIRLDGKIVSEE 491
VIHVAGT GKGST A +IL+ G+ ++SPHL ERI L + +S++
Sbjct: 49 VIHVAGTNGKGSTIAFLRAILQASGYSVNVYTSPHLRYFNERIVLRNREISDK 101
>UniRef50_A4B0Z4 Cluster: Bifunctional folylpolyglutamate
synthase/dihydrofolate synthase; n=1; Alteromonas
macleodii 'Deep ecotype'|Rep: Bifunctional
folylpolyglutamate synthase/dihydrofolate synthase -
Alteromonas macleodii 'Deep ecotype'
Length = 443
Score = 51.2 bits (117), Expect = 2e-05
Identities = 25/67 (37%), Positives = 37/67 (55%)
Frame = +3
Query: 318 LDELSVIHVAGTKGKGSTSAMCDSILRHHGFRTGFFSSPHLIAVRERIRLDGKIVSEEKF 497
L + VI VAGT GKG+T + + + G +SSPHL RER+R +G++ +F
Sbjct: 61 LSQSLVITVAGTNGKGTTCRLLEQAMLSQGKSVAVYSSPHLTDYRERVRYNGELPPANEF 120
Query: 498 AQHFHRV 518
+ F V
Sbjct: 121 VKAFEFV 127
>UniRef50_Q0USC9 Cluster: Putative uncharacterized protein; n=1;
Phaeosphaeria nodorum|Rep: Putative uncharacterized
protein - Phaeosphaeria nodorum (Septoria nodorum)
Length = 643
Score = 51.2 bits (117), Expect = 2e-05
Identities = 25/54 (46%), Positives = 34/54 (62%)
Frame = +3
Query: 336 IHVAGTKGKGSTSAMCDSILRHHGFRTGFFSSPHLIAVRERIRLDGKIVSEEKF 497
IHVAGT GKGS SIL+ R G F+SPHL+ + I+++G+ VS+ F
Sbjct: 23 IHVAGTNGKGSICHYAASILKRRTIRVGTFNSPHLVDRWDCIKINGEPVSKTSF 76
>UniRef50_UPI0000E0E8A2 Cluster: FolC bifunctional protein; n=1;
alpha proteobacterium HTCC2255|Rep: FolC bifunctional
protein - alpha proteobacterium HTCC2255
Length = 425
Score = 50.8 bits (116), Expect = 2e-05
Identities = 22/61 (36%), Positives = 37/61 (60%)
Frame = +3
Query: 327 LSVIHVAGTKGKGSTSAMCDSILRHHGFRTGFFSSPHLIAVRERIRLDGKIVSEEKFAQH 506
++VI VAGT GKG+T A ++ G+ G +SSPH+ ER+R++ +++ + Q
Sbjct: 45 VTVITVAGTNGKGTTCAFIEAAAIQCGYEVGVYSSPHINTYNERVRINQQLLDDTAHTQA 104
Query: 507 F 509
F
Sbjct: 105 F 105
>UniRef50_Q9X7F5 Cluster: FolC protein; n=1; Methylobacterium
chloromethanicum|Rep: FolC protein - Methylobacterium
chloromethanicum
Length = 467
Score = 50.8 bits (116), Expect = 2e-05
Identities = 24/45 (53%), Positives = 30/45 (66%)
Frame = +3
Query: 333 VIHVAGTKGKGSTSAMCDSILRHHGFRTGFFSSPHLIAVRERIRL 467
VIHVAGT GKGS A+ ++L G R ++SPHL+ ERIRL
Sbjct: 65 VIHVAGTNGKGSAIAVMRTLLEAGGLRVHTYTSPHLVHFNERIRL 109
>UniRef50_A7I0L8 Cluster: Folylpolyglutamate synthase; n=4;
Campylobacter|Rep: Folylpolyglutamate synthase -
Campylobacter hominis (strain ATCC BAA-381 / LMG 19568 /
NCTC 13146 /CH001A)
Length = 391
Score = 50.8 bits (116), Expect = 2e-05
Identities = 28/78 (35%), Positives = 40/78 (51%), Gaps = 1/78 (1%)
Frame = +3
Query: 273 DMERYLFRTGVTLTKLDEL-SVIHVAGTKGKGSTSAMCDSILRHHGFRTGFFSSPHLIAV 449
D ER+ K+ L +V + GT GKGST +L G G ++SPH+ +
Sbjct: 19 DFERFPRIFNFLKNKIPPLKNVTQIIGTNGKGSTGRFLAQMLMQKGADVGHYTSPHIFSF 78
Query: 450 RERIRLDGKIVSEEKFAQ 503
ER L+G+ VS+EK Q
Sbjct: 79 NERFWLNGEDVSDEKLQQ 96
>UniRef50_A6G512 Cluster: FolC bifunctional protein; n=1;
Plesiocystis pacifica SIR-1|Rep: FolC bifunctional
protein - Plesiocystis pacifica SIR-1
Length = 407
Score = 50.8 bits (116), Expect = 2e-05
Identities = 28/60 (46%), Positives = 34/60 (56%), Gaps = 1/60 (1%)
Frame = +3
Query: 333 VIHVAGTKGKGSTSAMCDSILRHHGFR-TGFFSSPHLIAVRERIRLDGKIVSEEKFAQHF 509
V V GT GKGSTSAM LR G G F+SPHL V ER+++DG V + + F
Sbjct: 47 VTQVVGTNGKGSTSAMLAHALRELGQGPVGLFTSPHLHRVGERVQVDGVAVEDAHVREEF 106
>UniRef50_A4CD05 Cluster: Bifunctional: folylpolyglutamate synthase;
dihydrofolate synthase; n=3; Alteromonadales|Rep:
Bifunctional: folylpolyglutamate synthase; dihydrofolate
synthase - Pseudoalteromonas tunicata D2
Length = 423
Score = 50.8 bits (116), Expect = 2e-05
Identities = 21/48 (43%), Positives = 33/48 (68%)
Frame = +3
Query: 333 VIHVAGTKGKGSTSAMCDSILRHHGFRTGFFSSPHLIAVRERIRLDGK 476
+I +AGT GKG+T+ +++L F G ++SPHLI ER+RL+G+
Sbjct: 50 IILIAGTNGKGTTARCLEALLLAQNFTVGTYASPHLIKYNERVRLNGQ 97
>UniRef50_Q11KL3 Cluster: FolC bifunctional protein; n=4;
Rhizobiales|Rep: FolC bifunctional protein -
Mesorhizobium sp. (strain BNC1)
Length = 440
Score = 50.4 bits (115), Expect = 3e-05
Identities = 34/89 (38%), Positives = 45/89 (50%), Gaps = 4/89 (4%)
Frame = +3
Query: 264 NLEDMERYLFRTGVTLTKLDELSVIHVAGTKGKGSTSAMCDSILRHHGFRTGFFSSPHLI 443
+LE + R L R G KL VIH+AGT GKGS +A ++L G +SPHL+
Sbjct: 22 SLERVGRLLQRLGDPQEKLPP--VIHIAGTNGKGSAAAFSRALLEASGRTVHVHTSPHLV 79
Query: 444 AVRERIRL----DGKIVSEEKFAQHFHRV 518
ER RL G+ V ++ A RV
Sbjct: 80 RWHERFRLGKPTGGEFVDDDVLADAVERV 108
>UniRef50_A6VWY8 Cluster: FolC bifunctional protein; n=2;
Marinomonas|Rep: FolC bifunctional protein - Marinomonas
sp. MWYL1
Length = 418
Score = 50.4 bits (115), Expect = 3e-05
Identities = 27/62 (43%), Positives = 33/62 (53%)
Frame = +3
Query: 333 VIHVAGTKGKGSTSAMCDSILRHHGFRTGFFSSPHLIAVRERIRLDGKIVSEEKFAQHFH 512
VI VAGT GKGST AM L + G ++SPH IA ERI L+ +E + F
Sbjct: 44 VITVAGTNGKGSTCAMLTQYLCAQNYSVGTYTSPHFIAFNERIALNDSPCDDEVLCRAFE 103
Query: 513 RV 518
V
Sbjct: 104 VV 105
>UniRef50_A6QBX4 Cluster: Folylpolyglutamate synthase; n=1;
Sulfurovum sp. NBC37-1|Rep: Folylpolyglutamate synthase
- Sulfurovum sp. (strain NBC37-1)
Length = 388
Score = 50.4 bits (115), Expect = 3e-05
Identities = 24/59 (40%), Positives = 33/59 (55%), Gaps = 1/59 (1%)
Frame = +3
Query: 318 LDELSVIHVAGTKGKGSTSAMCDSIL-RHHGFRTGFFSSPHLIAVRERIRLDGKIVSEE 491
+D +HV GT GKGST M + + G G FSSPH++ ERI ++G S+E
Sbjct: 36 IDRPKTVHVVGTNGKGSTGRMISHLAYQGAGLSVGHFSSPHILKFNERIWMNGSDASDE 94
>UniRef50_Q97AP2 Cluster: Folylpolyglutamate synthase; n=2;
Thermoplasma volcanium|Rep: Folylpolyglutamate synthase
- Thermoplasma volcanium
Length = 407
Score = 50.4 bits (115), Expect = 3e-05
Identities = 26/52 (50%), Positives = 33/52 (63%)
Frame = +3
Query: 336 IHVAGTKGKGSTSAMCDSILRHHGFRTGFFSSPHLIAVRERIRLDGKIVSEE 491
IH+ G+ GKGSTSA SILR F G ++SPHL ERI +D + V +E
Sbjct: 19 IHITGSNGKGSTSAFIYSILRQK-FSVGVYTSPHLERFNERIIVDNEEVPDE 69
>UniRef50_Q67SJ1 Cluster: Folylpolyglutamate synthase; n=1;
Symbiobacterium thermophilum|Rep: Folylpolyglutamate
synthase - Symbiobacterium thermophilum
Length = 437
Score = 50.0 bits (114), Expect = 4e-05
Identities = 24/62 (38%), Positives = 39/62 (62%)
Frame = +3
Query: 333 VIHVAGTKGKGSTSAMCDSILRHHGFRTGFFSSPHLIAVRERIRLDGKIVSEEKFAQHFH 512
V+H+ GT GKGS +AM ++ LR G R G ++SP L+ +ER++++ + E A+
Sbjct: 42 VVHITGTSGKGSVAAMVEAGLRAAGRRVGLYTSPPLMRFKERMQVNRAEIPEADVARLTA 101
Query: 513 RV 518
RV
Sbjct: 102 RV 103
>UniRef50_Q2HAU4 Cluster: Putative uncharacterized protein; n=1;
Chaetomium globosum|Rep: Putative uncharacterized
protein - Chaetomium globosum (Soil fungus)
Length = 338
Score = 50.0 bits (114), Expect = 4e-05
Identities = 27/54 (50%), Positives = 32/54 (59%)
Frame = +3
Query: 336 IHVAGTKGKGSTSAMCDSILRHHGFRTGFFSSPHLIAVRERIRLDGKIVSEEKF 497
IHVAGT GKGS A ++L G F+SPHLI + I +DGK VSE F
Sbjct: 23 IHVAGTNGKGSICAYLSTMLTASGLSHARFTSPHLIDRWDCIAIDGKPVSEAVF 76
Database: uniref50
Posted date: Oct 5, 2007 11:19 AM
Number of letters in database: 575,637,011
Number of sequences in database: 1,657,284
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 507,090,990
Number of Sequences: 1657284
Number of extensions: 9322766
Number of successful extensions: 25053
Number of sequences better than 10.0: 309
Number of HSP's better than 10.0 without gapping: 24335
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 25006
length of database: 575,637,011
effective HSP length: 96
effective length of database: 416,537,747
effective search space used: 38738010471
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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