Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= I10A02NGRL0006_M15
(569 letters)
Database: human
237,096 sequences; 76,859,062 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
U24253-1|AAC13871.1| 353|Homo sapiens folylpolyglutamate synthe... 129 8e-30
M98045-1|AAA35852.1| 545|Homo sapiens folylpolyglutamate synthe... 129 8e-30
BC064393-1|AAH64393.1| 587|Homo sapiens folylpolyglutamate synt... 129 8e-30
AL162586-11|CAI39770.1| 587|Homo sapiens folylpolyglutamate syn... 129 8e-30
AL162586-10|CAI39769.1| 375|Homo sapiens folylpolyglutamate syn... 129 8e-30
AL162586-14|CAI39773.1| 537|Homo sapiens folylpolyglutamate syn... 120 4e-27
AL162586-13|CAI39772.1| 265|Homo sapiens folylpolyglutamate syn... 120 4e-27
AL162586-12|CAI39771.1| 194|Homo sapiens folylpolyglutamate syn... 120 4e-27
BT006639-1|AAP35285.1| 174|Homo sapiens folylpolyglutamate synt... 89 1e-17
U40868-1|AAA87568.1| 486|Homo sapiens folylpolyglutamate synthe... 81 4e-15
U14939-1|AAA85815.1| 107|Homo sapiens folylpolyglutamate synthe... 64 4e-10
AY007211-2|AAL08406.1| 53|Homo sapiens folylpolyglutamate synt... 33 0.71
AY007211-1|AAL08407.1| 75|Homo sapiens folylpolyglutamate synt... 33 0.71
AL139333-5|CAI15284.1| 2369|Homo sapiens dopey family member 1 p... 32 1.2
AL139333-4|CAM21599.1| 2465|Homo sapiens dopey family member 1 p... 32 1.2
AL121716-2|CAI42426.1| 2369|Homo sapiens dopey family member 1 p... 32 1.2
AL121716-1|CAI42425.2| 2465|Homo sapiens dopey family member 1 p... 32 1.2
>U24253-1|AAC13871.1| 353|Homo sapiens folylpolyglutamate
synthetase protein.
Length = 353
Score = 129 bits (311), Expect = 8e-30
Identities = 61/119 (51%), Positives = 86/119 (72%)
Frame = +3
Query: 168 YEDAVHKLNKLQSNKSTIDQIRKDLRTGKRCTNLEDMERYLFRTGVTLTKLDELSVIHVA 347
Y+DAV LN LQ+N ++Q+++ + G T LE ME YL R+G+ + LD L++IHV
Sbjct: 45 YQDAVRMLNTLQTNAGYLEQVKR--QRGDPQTQLEAMELYLARSGLQVEDLDRLNIIHVT 102
Query: 348 GTKGKGSTSAMCDSILRHHGFRTGFFSSPHLIAVRERIRLDGKIVSEEKFAQHFHRVYN 524
GTKGKGST A + ILR +G +TGFFSSPHL+ VRERIR++G+ +S E F ++F R+Y+
Sbjct: 103 GTKGKGSTCAFTECILRSYGLKTGFFSSPHLVQVRERIRINGQPISPELFTKYFWRLYH 161
>M98045-1|AAA35852.1| 545|Homo sapiens folylpolyglutamate
synthetase protein.
Length = 545
Score = 129 bits (311), Expect = 8e-30
Identities = 61/119 (51%), Positives = 86/119 (72%)
Frame = +3
Query: 168 YEDAVHKLNKLQSNKSTIDQIRKDLRTGKRCTNLEDMERYLFRTGVTLTKLDELSVIHVA 347
Y+DAV LN LQ+N ++Q+++ + G T LE ME YL R+G+ + LD L++IHV
Sbjct: 3 YQDAVRMLNTLQTNAGYLEQVKR--QRGDPQTQLEAMELYLARSGLQVEDLDRLNIIHVT 60
Query: 348 GTKGKGSTSAMCDSILRHHGFRTGFFSSPHLIAVRERIRLDGKIVSEEKFAQHFHRVYN 524
GTKGKGST A + ILR +G +TGFFSSPHL+ VRERIR++G+ +S E F ++F R+Y+
Sbjct: 61 GTKGKGSTCAFTECILRSYGLKTGFFSSPHLVQVRERIRINGQPISPELFTKYFWRLYH 119
>BC064393-1|AAH64393.1| 587|Homo sapiens folylpolyglutamate
synthase protein.
Length = 587
Score = 129 bits (311), Expect = 8e-30
Identities = 61/119 (51%), Positives = 86/119 (72%)
Frame = +3
Query: 168 YEDAVHKLNKLQSNKSTIDQIRKDLRTGKRCTNLEDMERYLFRTGVTLTKLDELSVIHVA 347
Y+DAV LN LQ+N ++Q+++ + G T LE ME YL R+G+ + LD L++IHV
Sbjct: 45 YQDAVRMLNTLQTNAGYLEQVKR--QRGDPQTQLEAMELYLARSGLQVEDLDRLNIIHVT 102
Query: 348 GTKGKGSTSAMCDSILRHHGFRTGFFSSPHLIAVRERIRLDGKIVSEEKFAQHFHRVYN 524
GTKGKGST A + ILR +G +TGFFSSPHL+ VRERIR++G+ +S E F ++F R+Y+
Sbjct: 103 GTKGKGSTCAFTECILRSYGLKTGFFSSPHLVQVRERIRINGQPISPELFTKYFWRLYH 161
>AL162586-11|CAI39770.1| 587|Homo sapiens folylpolyglutamate
synthase protein.
Length = 587
Score = 129 bits (311), Expect = 8e-30
Identities = 61/119 (51%), Positives = 86/119 (72%)
Frame = +3
Query: 168 YEDAVHKLNKLQSNKSTIDQIRKDLRTGKRCTNLEDMERYLFRTGVTLTKLDELSVIHVA 347
Y+DAV LN LQ+N ++Q+++ + G T LE ME YL R+G+ + LD L++IHV
Sbjct: 45 YQDAVRMLNTLQTNAGYLEQVKR--QRGDPQTQLEAMELYLARSGLQVEDLDRLNIIHVT 102
Query: 348 GTKGKGSTSAMCDSILRHHGFRTGFFSSPHLIAVRERIRLDGKIVSEEKFAQHFHRVYN 524
GTKGKGST A + ILR +G +TGFFSSPHL+ VRERIR++G+ +S E F ++F R+Y+
Sbjct: 103 GTKGKGSTCAFTECILRSYGLKTGFFSSPHLVQVRERIRINGQPISPELFTKYFWRLYH 161
>AL162586-10|CAI39769.1| 375|Homo sapiens folylpolyglutamate
synthase protein.
Length = 375
Score = 129 bits (311), Expect = 8e-30
Identities = 61/119 (51%), Positives = 86/119 (72%)
Frame = +3
Query: 168 YEDAVHKLNKLQSNKSTIDQIRKDLRTGKRCTNLEDMERYLFRTGVTLTKLDELSVIHVA 347
Y+DAV LN LQ+N ++Q+++ + G T LE ME YL R+G+ + LD L++IHV
Sbjct: 45 YQDAVRMLNTLQTNAGYLEQVKR--QRGDPQTQLEAMELYLARSGLQVEDLDRLNIIHVT 102
Query: 348 GTKGKGSTSAMCDSILRHHGFRTGFFSSPHLIAVRERIRLDGKIVSEEKFAQHFHRVYN 524
GTKGKGST A + ILR +G +TGFFSSPHL+ VRERIR++G+ +S E F ++F R+Y+
Sbjct: 103 GTKGKGSTCAFTECILRSYGLKTGFFSSPHLVQVRERIRINGQPISPELFTKYFWRLYH 161
>AL162586-14|CAI39773.1| 537|Homo sapiens folylpolyglutamate
synthase protein.
Length = 537
Score = 120 bits (289), Expect = 4e-27
Identities = 57/112 (50%), Positives = 81/112 (72%)
Frame = +3
Query: 189 LNKLQSNKSTIDQIRKDLRTGKRCTNLEDMERYLFRTGVTLTKLDELSVIHVAGTKGKGS 368
LN LQ+N ++Q+++ + G T LE ME YL R+G+ + LD L++IHV GTKGKGS
Sbjct: 2 LNTLQTNAGYLEQVKR--QRGDPQTQLEAMELYLARSGLQVEDLDRLNIIHVTGTKGKGS 59
Query: 369 TSAMCDSILRHHGFRTGFFSSPHLIAVRERIRLDGKIVSEEKFAQHFHRVYN 524
T A + ILR +G +TGFFSSPHL+ VRERIR++G+ +S E F ++F R+Y+
Sbjct: 60 TCAFTECILRSYGLKTGFFSSPHLVQVRERIRINGQPISPELFTKYFWRLYH 111
>AL162586-13|CAI39772.1| 265|Homo sapiens folylpolyglutamate
synthase protein.
Length = 265
Score = 120 bits (289), Expect = 4e-27
Identities = 57/112 (50%), Positives = 81/112 (72%)
Frame = +3
Query: 189 LNKLQSNKSTIDQIRKDLRTGKRCTNLEDMERYLFRTGVTLTKLDELSVIHVAGTKGKGS 368
LN LQ+N ++Q+++ + G T LE ME YL R+G+ + LD L++IHV GTKGKGS
Sbjct: 2 LNTLQTNAGYLEQVKR--QRGDPQTQLEAMELYLARSGLQVEDLDRLNIIHVTGTKGKGS 59
Query: 369 TSAMCDSILRHHGFRTGFFSSPHLIAVRERIRLDGKIVSEEKFAQHFHRVYN 524
T A + ILR +G +TGFFSSPHL+ VRERIR++G+ +S E F ++F R+Y+
Sbjct: 60 TCAFTECILRSYGLKTGFFSSPHLVQVRERIRINGQPISPELFTKYFWRLYH 111
>AL162586-12|CAI39771.1| 194|Homo sapiens folylpolyglutamate
synthase protein.
Length = 194
Score = 120 bits (289), Expect = 4e-27
Identities = 57/112 (50%), Positives = 81/112 (72%)
Frame = +3
Query: 189 LNKLQSNKSTIDQIRKDLRTGKRCTNLEDMERYLFRTGVTLTKLDELSVIHVAGTKGKGS 368
LN LQ+N ++Q+++ + G T LE ME YL R+G+ + LD L++IHV GTKGKGS
Sbjct: 2 LNTLQTNAGYLEQVKR--QRGDPQTQLEAMELYLARSGLQVEDLDRLNIIHVTGTKGKGS 59
Query: 369 TSAMCDSILRHHGFRTGFFSSPHLIAVRERIRLDGKIVSEEKFAQHFHRVYN 524
T A + ILR +G +TGFFSSPHL+ VRERIR++G+ +S E F ++F R+Y+
Sbjct: 60 TCAFTECILRSYGLKTGFFSSPHLVQVRERIRINGQPISPELFTKYFWRLYH 111
>BT006639-1|AAP35285.1| 174|Homo sapiens folylpolyglutamate
synthase protein.
Length = 174
Score = 89.0 bits (211), Expect = 1e-17
Identities = 43/86 (50%), Positives = 59/86 (68%)
Frame = +3
Query: 168 YEDAVHKLNKLQSNKSTIDQIRKDLRTGKRCTNLEDMERYLFRTGVTLTKLDELSVIHVA 347
Y+DAV LN LQ+N ++Q+++ + G T LE ME YL R+G+ + LD L++IHV
Sbjct: 45 YQDAVRMLNTLQTNAGYLEQVKR--QRGDPQTQLEAMELYLARSGLQVEDLDRLNIIHVT 102
Query: 348 GTKGKGSTSAMCDSILRHHGFRTGFF 425
GTKGKGST A + ILR +G +TGFF
Sbjct: 103 GTKGKGSTCAFTECILRSYGLKTGFF 128
>U40868-1|AAA87568.1| 486|Homo sapiens folylpolyglutamate
synthetase protein.
Length = 486
Score = 80.6 bits (190), Expect = 4e-15
Identities = 35/59 (59%), Positives = 47/59 (79%)
Frame = +3
Query: 348 GTKGKGSTSAMCDSILRHHGFRTGFFSSPHLIAVRERIRLDGKIVSEEKFAQHFHRVYN 524
GTKGKGST A + ILR +G +TGFFSSPHL+ VRERIR++G+ +S E F ++F R+Y+
Sbjct: 2 GTKGKGSTCAFTECILRSYGLKTGFFSSPHLVQVRERIRINGQPISPELFTKYFWRLYH 60
>U14939-1|AAA85815.1| 107|Homo sapiens folylpolyglutamate
synthetase protein.
Length = 107
Score = 63.7 bits (148), Expect = 4e-10
Identities = 31/65 (47%), Positives = 44/65 (67%)
Frame = +3
Query: 168 YEDAVHKLNKLQSNKSTIDQIRKDLRTGKRCTNLEDMERYLFRTGVTLTKLDELSVIHVA 347
Y+DAV LN LQ+N ++Q+++ + G T LE ME YL R+G+ + LD L++IHV
Sbjct: 45 YQDAVRMLNTLQTNAGYLEQVKR--QRGDPQTQLEAMELYLARSGLQVEDLDRLNIIHVT 102
Query: 348 GTKGK 362
GTKGK
Sbjct: 103 GTKGK 107
>AY007211-2|AAL08406.1| 53|Homo sapiens folylpolyglutamate
synthetase cytosolic isoform protein.
Length = 53
Score = 33.1 bits (72), Expect = 0.71
Identities = 16/42 (38%), Positives = 27/42 (64%)
Frame = +3
Query: 162 SNYEDAVHKLNKLQSNKSTIDQIRKDLRTGKRCTNLEDMERY 287
++++DAV LN LQ+N ++Q+++ + G T LE ME Y
Sbjct: 14 ASFQDAVRMLNTLQTNAGYLEQVKR--QRGDPQTQLEAMELY 53
>AY007211-1|AAL08407.1| 75|Homo sapiens folylpolyglutamate
synthetase mitochondrial isoform protein.
Length = 75
Score = 33.1 bits (72), Expect = 0.71
Identities = 16/42 (38%), Positives = 27/42 (64%)
Frame = +3
Query: 162 SNYEDAVHKLNKLQSNKSTIDQIRKDLRTGKRCTNLEDMERY 287
++++DAV LN LQ+N ++Q+++ + G T LE ME Y
Sbjct: 36 ASFQDAVRMLNTLQTNAGYLEQVKR--QRGDPQTQLEAMELY 75
>AL139333-5|CAI15284.1| 2369|Homo sapiens dopey family member 1
protein.
Length = 2369
Score = 32.3 bits (70), Expect = 1.2
Identities = 19/59 (32%), Positives = 32/59 (54%), Gaps = 5/59 (8%)
Frame = +3
Query: 96 MCSSSLYRSYL--VNKLVRMYSVKSNYED---AVHKLNKLQSNKSTIDQIRKDLRTGKR 257
+ S S YR+Y+ ++K ++ + S + D A+ KLNK+ N + + K L GKR
Sbjct: 8 LLSDSKYRNYVAAIDKALKNFEYSSEWADLISALGKLNKVLQNNAKYQVVPKKLTIGKR 66
>AL139333-4|CAM21599.1| 2465|Homo sapiens dopey family member 1
protein.
Length = 2465
Score = 32.3 bits (70), Expect = 1.2
Identities = 19/59 (32%), Positives = 32/59 (54%), Gaps = 5/59 (8%)
Frame = +3
Query: 96 MCSSSLYRSYL--VNKLVRMYSVKSNYED---AVHKLNKLQSNKSTIDQIRKDLRTGKR 257
+ S S YR+Y+ ++K ++ + S + D A+ KLNK+ N + + K L GKR
Sbjct: 8 LLSDSKYRNYVAAIDKALKNFEYSSEWADLISALGKLNKVLQNNAKYQVVPKKLTIGKR 66
>AL121716-2|CAI42426.1| 2369|Homo sapiens dopey family member 1
protein.
Length = 2369
Score = 32.3 bits (70), Expect = 1.2
Identities = 19/59 (32%), Positives = 32/59 (54%), Gaps = 5/59 (8%)
Frame = +3
Query: 96 MCSSSLYRSYL--VNKLVRMYSVKSNYED---AVHKLNKLQSNKSTIDQIRKDLRTGKR 257
+ S S YR+Y+ ++K ++ + S + D A+ KLNK+ N + + K L GKR
Sbjct: 8 LLSDSKYRNYVAAIDKALKNFEYSSEWADLISALGKLNKVLQNNAKYQVVPKKLTIGKR 66
>AL121716-1|CAI42425.2| 2465|Homo sapiens dopey family member 1
protein.
Length = 2465
Score = 32.3 bits (70), Expect = 1.2
Identities = 19/59 (32%), Positives = 32/59 (54%), Gaps = 5/59 (8%)
Frame = +3
Query: 96 MCSSSLYRSYL--VNKLVRMYSVKSNYED---AVHKLNKLQSNKSTIDQIRKDLRTGKR 257
+ S S YR+Y+ ++K ++ + S + D A+ KLNK+ N + + K L GKR
Sbjct: 8 LLSDSKYRNYVAAIDKALKNFEYSSEWADLISALGKLNKVLQNNAKYQVVPKKLTIGKR 66
Database: human
Posted date: Oct 23, 2007 1:18 PM
Number of letters in database: 76,859,062
Number of sequences in database: 237,096
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 72,817,849
Number of Sequences: 237096
Number of extensions: 1420437
Number of successful extensions: 6328
Number of sequences better than 10.0: 17
Number of HSP's better than 10.0 without gapping: 6281
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 6321
length of database: 76,859,062
effective HSP length: 86
effective length of database: 56,468,806
effective search space used: 5816287018
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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