Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= I10A02NGRL0006_D23
(519 letters)
Database: human
237,096 sequences; 76,859,062 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
M31786-1|AAA35531.1| 589|Homo sapiens protein ( Human medium tu... 256 4e-68
J02902-1|AAA36399.1| 589|Homo sapiens phosphatase 2A regulatory... 256 4e-68
BC001537-1|AAH01537.1| 589|Homo sapiens protein phosphatase 2 (... 256 4e-68
AK091387-1|BAC03652.1| 509|Homo sapiens protein ( Homo sapiens ... 256 4e-68
CR450340-1|CAG29336.1| 589|Homo sapiens PPP2R1A protein. 253 3e-67
M65254-1|AAA59983.1| 575|Homo sapiens protein phosphatase-2A re... 244 1e-64
BC027596-1|AAH27596.1| 667|Homo sapiens protein phosphatase 2 (... 244 1e-64
AF163473-1|AAG39644.1| 601|Homo sapiens protein phosphatase 2A ... 244 1e-64
AF087438-1|AAC69624.1| 601|Homo sapiens protein phosphatase 2 s... 244 1e-64
AF083439-1|AAC63525.1| 601|Homo sapiens protein phosphatase 2A ... 244 1e-64
BC060829-1|AAH60829.1| 933|Homo sapiens protein phosphatase 4, ... 38 0.021
AF200478-1|AAL78298.1| 950|Homo sapiens protein serine/threonin... 38 0.021
AF111106-1|AAD09818.1| 933|Homo sapiens protein serine/threonin... 38 0.021
BC068491-1|AAH68491.1| 873|Homo sapiens KIAA1622 protein. 37 0.037
AB046842-1|BAB13448.1| 892|Homo sapiens KIAA1622 protein protein. 37 0.037
U79267-1|AAB50211.1| 173|Homo sapiens unknown protein. 32 1.0
BC089393-1|AAH89393.1| 209|Homo sapiens tripartite motif-contai... 31 3.2
BC032762-1|AAH32762.1| 571|Homo sapiens OPTN protein protein. 29 7.4
BC013876-1|AAH13876.1| 577|Homo sapiens optineurin protein. 29 7.4
AL355355-6|CAI16550.1| 571|Homo sapiens optineurin protein. 29 7.4
AL355355-5|CAI16549.1| 577|Homo sapiens optineurin protein. 29 7.4
AF420373-1|AAL76329.1| 577|Homo sapiens optineurin isoform 3 pr... 29 7.4
AF420372-1|AAL76328.1| 577|Homo sapiens optineurin isoform 2 pr... 29 7.4
AF420371-1|AAL76327.1| 577|Homo sapiens optineurin isoform 1 pr... 29 7.4
>M31786-1|AAA35531.1| 589|Homo sapiens protein ( Human medium tumor
antigen-associated 61-kD protein mRNA, 5' end. ).
Length = 589
Score = 256 bits (626), Expect = 4e-68
Identities = 119/158 (75%), Positives = 135/158 (85%)
Frame = +1
Query: 1 VELAEDTKWRVRLAIIEHMPLLAGQLGQEFFDEKLTGLCMSWLIDHVYAIREAATLNLKK 180
VELAED KWRVRLAIIE+MPLLAGQLG EFFDEKL LCM+WL+DHVYAIREAAT NLKK
Sbjct: 409 VELAEDAKWRVRLAIIEYMPLLAGQLGVEFFDEKLNSLCMAWLVDHVYAIREAATSNLKK 468
Query: 181 LVEQYGSTWAETNVIPKVLTMSREQNYLHRMTYLFCINVLSEVCGKDITTRVLLPTVLSM 360
LVE++G WA +IPKVL MS + NYLHRMT LFCINVLSEVCG+DITT+ +LPTVL M
Sbjct: 469 LVEKFGKEWAHATIIPKVLAMSGDPNYLHRMTTLFCINVLSEVCGQDITTKHMLPTVLRM 528
Query: 361 ADDSVANVRFNVAKTLQKMAPFLDPAVIQPQVKPVLEK 474
A D VANVRFNVAK+LQK+ P LD + +Q +VKP+LEK
Sbjct: 529 AGDPVANVRFNVAKSLQKIGPILDNSTLQSEVKPILEK 566
Score = 50.4 bits (115), Expect = 4e-06
Identities = 36/139 (25%), Positives = 57/139 (41%), Gaps = 4/139 (2%)
Frame = +1
Query: 4 ELAEDTKWRVRLAIIEHMPLLAGQLGQEFFDEKLTGLCMSWLIDHVYAIREAATLNLKKL 183
+ AED WRVR + + L +G E L + + D +R AA+ +K+
Sbjct: 250 QAAEDKSWRVRYMVADKFTELQKAVGPEITKTDLVPAFQNLMKDCEAEVRAAASHKVKEF 309
Query: 184 VEQYGSTWAE----TNVIPKVLTMSREQNYLHRMTYLFCINVLSEVCGKDITTRVLLPTV 351
E + E + ++P + + + N + I LS + GKD T LLP
Sbjct: 310 CENLSADCRENVIMSQILPCIKELVSDANQHVKSALASVIMGLSPILGKDNTIEHLLPLF 369
Query: 352 LSMADDSVANVRFNVAKTL 408
L+ D VR N+ L
Sbjct: 370 LAQLKDECPEVRLNIISNL 388
Score = 35.9 bits (79), Expect = 0.085
Identities = 26/126 (20%), Positives = 54/126 (42%), Gaps = 1/126 (0%)
Frame = +1
Query: 133 DHVYAIREAATLNLKKLVEQYGSTWAETNVIPKVLTM-SREQNYLHRMTYLFCINVLSEV 309
D +R AA L + + ++ +IP + S EQ+ + + C+N+ +
Sbjct: 176 DDTPMVRRAAASKLGEFAKVLELDNVKSEIIPMFSNLASDEQDSVRLLAVEACVNIAQLL 235
Query: 310 CGKDITTRVLLPTVLSMADDSVANVRFNVAKTLQKMAPFLDPAVIQPQVKPVLEKFER*S 489
+D+ V+ PT+ A+D VR+ VA ++ + P + + + P + +
Sbjct: 236 PQEDLEALVM-PTLRQAAEDKSWRVRYMVADKFTELQKAVGPEITKTDLVPAFQNLMK-- 292
Query: 490 RCRCEI 507
C E+
Sbjct: 293 DCEAEV 298
>J02902-1|AAA36399.1| 589|Homo sapiens phosphatase 2A regulatory
subunit protein.
Length = 589
Score = 256 bits (626), Expect = 4e-68
Identities = 119/158 (75%), Positives = 135/158 (85%)
Frame = +1
Query: 1 VELAEDTKWRVRLAIIEHMPLLAGQLGQEFFDEKLTGLCMSWLIDHVYAIREAATLNLKK 180
VELAED KWRVRLAIIE+MPLLAGQLG EFFDEKL LCM+WL+DHVYAIREAAT NLKK
Sbjct: 409 VELAEDAKWRVRLAIIEYMPLLAGQLGVEFFDEKLNSLCMAWLVDHVYAIREAATSNLKK 468
Query: 181 LVEQYGSTWAETNVIPKVLTMSREQNYLHRMTYLFCINVLSEVCGKDITTRVLLPTVLSM 360
LVE++G WA +IPKVL MS + NYLHRMT LFCINVLSEVCG+DITT+ +LPTVL M
Sbjct: 469 LVEKFGKEWAHATIIPKVLAMSGDPNYLHRMTTLFCINVLSEVCGQDITTKHMLPTVLRM 528
Query: 361 ADDSVANVRFNVAKTLQKMAPFLDPAVIQPQVKPVLEK 474
A D VANVRFNVAK+LQK+ P LD + +Q +VKP+LEK
Sbjct: 529 AGDPVANVRFNVAKSLQKIGPILDNSTLQSEVKPILEK 566
Score = 48.0 bits (109), Expect = 2e-05
Identities = 36/139 (25%), Positives = 56/139 (40%), Gaps = 4/139 (2%)
Frame = +1
Query: 4 ELAEDTKWRVRLAIIEHMPLLAGQLGQEFFDEKLTGLCMSWLIDHVYAIREAATLNLKKL 183
+ AED W VR + + L +G E L + + D +R AA+ +K+
Sbjct: 250 QAAEDKSWAVRYMVADKFTELQKAVGPEITKTDLVPAFQNLMKDCEAEVRAAASHKVKEF 309
Query: 184 VEQYGSTWAETNVIPKVLTMSRE----QNYLHRMTYLFCINVLSEVCGKDITTRVLLPTV 351
E + E ++ ++L +E N + I LS + GKD T LLP
Sbjct: 310 CENLSADCRENVIMSQILPCIKELVSDANQHVKSALASVIMGLSPILGKDNTIEHLLPLF 369
Query: 352 LSMADDSVANVRFNVAKTL 408
L+ D VR N+ L
Sbjct: 370 LAQLKDECPEVRLNIISNL 388
Score = 35.1 bits (77), Expect = 0.15
Identities = 26/126 (20%), Positives = 54/126 (42%), Gaps = 1/126 (0%)
Frame = +1
Query: 133 DHVYAIREAATLNLKKLVEQYGSTWAETNVIPKVLTM-SREQNYLHRMTYLFCINVLSEV 309
D +R AA L + + ++ +IP + S EQ+ + + C+N+ +
Sbjct: 176 DDTPMVRRAAASKLGEFAKVLELDNVKSEIIPMFSNLASDEQDSVRLLAVEACVNIAQLL 235
Query: 310 CGKDITTRVLLPTVLSMADDSVANVRFNVAKTLQKMAPFLDPAVIQPQVKPVLEKFER*S 489
+D+ V+ PT+ A+D VR+ VA ++ + P + + + P + +
Sbjct: 236 PQEDLEALVM-PTLRQAAEDKSWAVRYMVADKFTELQKAVGPEITKTDLVPAFQNLMK-- 292
Query: 490 RCRCEI 507
C E+
Sbjct: 293 DCEAEV 298
>BC001537-1|AAH01537.1| 589|Homo sapiens protein phosphatase 2
(formerly 2A), regulatory subunit A , alpha isoform
protein.
Length = 589
Score = 256 bits (626), Expect = 4e-68
Identities = 119/158 (75%), Positives = 135/158 (85%)
Frame = +1
Query: 1 VELAEDTKWRVRLAIIEHMPLLAGQLGQEFFDEKLTGLCMSWLIDHVYAIREAATLNLKK 180
VELAED KWRVRLAIIE+MPLLAGQLG EFFDEKL LCM+WL+DHVYAIREAAT NLKK
Sbjct: 409 VELAEDAKWRVRLAIIEYMPLLAGQLGVEFFDEKLNSLCMAWLVDHVYAIREAATSNLKK 468
Query: 181 LVEQYGSTWAETNVIPKVLTMSREQNYLHRMTYLFCINVLSEVCGKDITTRVLLPTVLSM 360
LVE++G WA +IPKVL MS + NYLHRMT LFCINVLSEVCG+DITT+ +LPTVL M
Sbjct: 469 LVEKFGKEWAHATIIPKVLAMSGDPNYLHRMTTLFCINVLSEVCGQDITTKHMLPTVLRM 528
Query: 361 ADDSVANVRFNVAKTLQKMAPFLDPAVIQPQVKPVLEK 474
A D VANVRFNVAK+LQK+ P LD + +Q +VKP+LEK
Sbjct: 529 AGDPVANVRFNVAKSLQKIGPILDNSTLQSEVKPILEK 566
Score = 50.4 bits (115), Expect = 4e-06
Identities = 36/139 (25%), Positives = 57/139 (41%), Gaps = 4/139 (2%)
Frame = +1
Query: 4 ELAEDTKWRVRLAIIEHMPLLAGQLGQEFFDEKLTGLCMSWLIDHVYAIREAATLNLKKL 183
+ AED WRVR + + L +G E L + + D +R AA+ +K+
Sbjct: 250 QAAEDKSWRVRYMVADKFTELQKAVGPEITKTDLVPAFQNLMKDCEAEVRAAASHKVKEF 309
Query: 184 VEQYGSTWAE----TNVIPKVLTMSREQNYLHRMTYLFCINVLSEVCGKDITTRVLLPTV 351
E + E + ++P + + + N + I LS + GKD T LLP
Sbjct: 310 CENLSADCRENVIMSQILPCIKELVSDANQHVKSALASVIMGLSPILGKDNTIEHLLPLF 369
Query: 352 LSMADDSVANVRFNVAKTL 408
L+ D VR N+ L
Sbjct: 370 LAQLKDECPEVRLNIISNL 388
Score = 35.9 bits (79), Expect = 0.085
Identities = 26/126 (20%), Positives = 54/126 (42%), Gaps = 1/126 (0%)
Frame = +1
Query: 133 DHVYAIREAATLNLKKLVEQYGSTWAETNVIPKVLTM-SREQNYLHRMTYLFCINVLSEV 309
D +R AA L + + ++ +IP + S EQ+ + + C+N+ +
Sbjct: 176 DDTPMVRRAAASKLGEFAKVLELDNVKSEIIPMFSNLASDEQDSVRLLAVEACVNIAQLL 235
Query: 310 CGKDITTRVLLPTVLSMADDSVANVRFNVAKTLQKMAPFLDPAVIQPQVKPVLEKFER*S 489
+D+ V+ PT+ A+D VR+ VA ++ + P + + + P + +
Sbjct: 236 PQEDLEALVM-PTLRQAAEDKSWRVRYMVADKFTELQKAVGPEITKTDLVPAFQNLMK-- 292
Query: 490 RCRCEI 507
C E+
Sbjct: 293 DCEAEV 298
>AK091387-1|BAC03652.1| 509|Homo sapiens protein ( Homo sapiens
cDNA FLJ34068 fis, clone FCBBF3001918, highly similar to
SERINE/THREONINE PROTEIN PHOSPHATASE 2A, 65 KDA
REGULATORY ).
Length = 509
Score = 256 bits (626), Expect = 4e-68
Identities = 119/158 (75%), Positives = 135/158 (85%)
Frame = +1
Query: 1 VELAEDTKWRVRLAIIEHMPLLAGQLGQEFFDEKLTGLCMSWLIDHVYAIREAATLNLKK 180
VELAED KWRVRLAIIE+MPLLAGQLG EFFDEKL LCM+WL+DHVYAIREAAT NLKK
Sbjct: 329 VELAEDAKWRVRLAIIEYMPLLAGQLGVEFFDEKLNSLCMAWLVDHVYAIREAATSNLKK 388
Query: 181 LVEQYGSTWAETNVIPKVLTMSREQNYLHRMTYLFCINVLSEVCGKDITTRVLLPTVLSM 360
LVE++G WA +IPKVL MS + NYLHRMT LFCINVLSEVCG+DITT+ +LPTVL M
Sbjct: 389 LVEKFGKEWAHATIIPKVLAMSGDPNYLHRMTTLFCINVLSEVCGQDITTKHMLPTVLRM 448
Query: 361 ADDSVANVRFNVAKTLQKMAPFLDPAVIQPQVKPVLEK 474
A D VANVRFNVAK+LQK+ P LD + +Q +VKP+LEK
Sbjct: 449 AGDPVANVRFNVAKSLQKIGPILDNSTLQSEVKPILEK 486
Score = 50.4 bits (115), Expect = 4e-06
Identities = 36/139 (25%), Positives = 57/139 (41%), Gaps = 4/139 (2%)
Frame = +1
Query: 4 ELAEDTKWRVRLAIIEHMPLLAGQLGQEFFDEKLTGLCMSWLIDHVYAIREAATLNLKKL 183
+ AED WRVR + + L +G E L + + D +R AA+ +K+
Sbjct: 170 QAAEDKSWRVRYMVADKFTELQKAVGPEITKTDLVPAFQNLMKDCEAEVRAAASHKVKEF 229
Query: 184 VEQYGSTWAE----TNVIPKVLTMSREQNYLHRMTYLFCINVLSEVCGKDITTRVLLPTV 351
E + E + ++P + + + N + I LS + GKD T LLP
Sbjct: 230 CENLSADCRENVIMSQILPCIKELVSDANQHVKSALASVIMGLSPILGKDNTIEHLLPLF 289
Query: 352 LSMADDSVANVRFNVAKTL 408
L+ D VR N+ L
Sbjct: 290 LAQLKDECPEVRLNIISNL 308
Score = 35.9 bits (79), Expect = 0.085
Identities = 26/126 (20%), Positives = 54/126 (42%), Gaps = 1/126 (0%)
Frame = +1
Query: 133 DHVYAIREAATLNLKKLVEQYGSTWAETNVIPKVLTM-SREQNYLHRMTYLFCINVLSEV 309
D +R AA L + + ++ +IP + S EQ+ + + C+N+ +
Sbjct: 96 DDTPMVRRAAASKLGEFAKVLELDNVKSEIIPMFSNLASDEQDSVRLLAVEACVNIAQLL 155
Query: 310 CGKDITTRVLLPTVLSMADDSVANVRFNVAKTLQKMAPFLDPAVIQPQVKPVLEKFER*S 489
+D+ V+ PT+ A+D VR+ VA ++ + P + + + P + +
Sbjct: 156 PQEDLEALVM-PTLRQAAEDKSWRVRYMVADKFTELQKAVGPEITKTDLVPAFQNLMK-- 212
Query: 490 RCRCEI 507
C E+
Sbjct: 213 DCEAEV 218
>CR450340-1|CAG29336.1| 589|Homo sapiens PPP2R1A protein.
Length = 589
Score = 253 bits (619), Expect = 3e-67
Identities = 118/158 (74%), Positives = 134/158 (84%)
Frame = +1
Query: 1 VELAEDTKWRVRLAIIEHMPLLAGQLGQEFFDEKLTGLCMSWLIDHVYAIREAATLNLKK 180
VELAED KWRVRLAIIE+MPLLAGQLG EFFDEKL LCM+WL+DHVYAIREAAT NLKK
Sbjct: 409 VELAEDAKWRVRLAIIEYMPLLAGQLGVEFFDEKLNSLCMAWLVDHVYAIREAATSNLKK 468
Query: 181 LVEQYGSTWAETNVIPKVLTMSREQNYLHRMTYLFCINVLSEVCGKDITTRVLLPTVLSM 360
LVE++G WA +IPKVL MS + NYLHRMT LFCINVLSEVCG+DITT+ +LPTVL M
Sbjct: 469 LVEKFGKEWAHATIIPKVLAMSGDPNYLHRMTTLFCINVLSEVCGQDITTKHMLPTVLRM 528
Query: 361 ADDSVANVRFNVAKTLQKMAPFLDPAVIQPQVKPVLEK 474
A D VANVRFNVAK+LQK+ P D + +Q +VKP+LEK
Sbjct: 529 AGDPVANVRFNVAKSLQKIGPIPDNSTLQSEVKPILEK 566
Score = 50.4 bits (115), Expect = 4e-06
Identities = 36/139 (25%), Positives = 57/139 (41%), Gaps = 4/139 (2%)
Frame = +1
Query: 4 ELAEDTKWRVRLAIIEHMPLLAGQLGQEFFDEKLTGLCMSWLIDHVYAIREAATLNLKKL 183
+ AED WRVR + + L +G E L + + D +R AA+ +K+
Sbjct: 250 QAAEDKSWRVRYMVADKFTELQKAVGPEITKTDLVPAFQNLMKDCEAEVRAAASHKVKEF 309
Query: 184 VEQYGSTWAE----TNVIPKVLTMSREQNYLHRMTYLFCINVLSEVCGKDITTRVLLPTV 351
E + E + ++P + + + N + I LS + GKD T LLP
Sbjct: 310 CENLSADCRENVIMSQILPCIKELVSDANQHVKSALASVIMGLSPILGKDNTIEHLLPLF 369
Query: 352 LSMADDSVANVRFNVAKTL 408
L+ D VR N+ L
Sbjct: 370 LAQLKDECPEVRLNIISNL 388
Score = 35.9 bits (79), Expect = 0.085
Identities = 26/126 (20%), Positives = 54/126 (42%), Gaps = 1/126 (0%)
Frame = +1
Query: 133 DHVYAIREAATLNLKKLVEQYGSTWAETNVIPKVLTM-SREQNYLHRMTYLFCINVLSEV 309
D +R AA L + + ++ +IP + S EQ+ + + C+N+ +
Sbjct: 176 DDTPMVRRAAASKLGEFAKVLELDNVKSEIIPMFSNLASDEQDSVRLLAVEACVNIAQLL 235
Query: 310 CGKDITTRVLLPTVLSMADDSVANVRFNVAKTLQKMAPFLDPAVIQPQVKPVLEKFER*S 489
+D+ V+ PT+ A+D VR+ VA ++ + P + + + P + +
Sbjct: 236 PQEDLEALVM-PTLRQAAEDKSWRVRYMVADKFTELQKAVGPEITKTDLVPAFQNLMK-- 292
Query: 490 RCRCEI 507
C E+
Sbjct: 293 DCEAEV 298
>M65254-1|AAA59983.1| 575|Homo sapiens protein phosphatase-2A
regulatory subunit-beta protein.
Length = 575
Score = 244 bits (597), Expect = 1e-64
Identities = 111/158 (70%), Positives = 132/158 (83%)
Frame = +1
Query: 1 VELAEDTKWRVRLAIIEHMPLLAGQLGQEFFDEKLTGLCMSWLIDHVYAIREAATLNLKK 180
VELAED KWRVRLAIIE+MPLLAGQLG EFFDEKL LCM+WL+DHVYAIREAAT NL K
Sbjct: 395 VELAEDAKWRVRLAIIEYMPLLAGQLGVEFFDEKLNSLCMAWLVDHVYAIREAATNNLMK 454
Query: 181 LVEQYGSTWAETNVIPKVLTMSREQNYLHRMTYLFCINVLSEVCGKDITTRVLLPTVLSM 360
LV+++G+ WA+ ++PKVL M+ + NYLHRMT LFCIN LSE CG++ITT+ +LP VL M
Sbjct: 455 LVQKFGTEWAQNTIVPKVLVMANDPNYLHRMTTLFCINALSEACGQEITTKQMLPIVLKM 514
Query: 361 ADDSVANVRFNVAKTLQKMAPFLDPAVIQPQVKPVLEK 474
A D VANVRFNVAK+LQK+ P LD +Q +VKPVL+K
Sbjct: 515 AGDQVANVRFNVAKSLQKIGPILDTNALQGEVKPVLQK 552
Score = 47.6 bits (108), Expect = 3e-05
Identities = 37/139 (26%), Positives = 57/139 (41%), Gaps = 4/139 (2%)
Frame = +1
Query: 4 ELAEDTKWRVRLAIIEHMPLLAGQLGQEFFDEKLTGLCMSWLIDHVYAIREAATLNLKKL 183
+ AED WRVR + + L +G + L + L D +R AA +K+L
Sbjct: 236 QAAEDKSWRVRYMVADRFSELQKAMGPKITLNDLIPAFQNLLKDCEAEVRAAAAHKVKEL 295
Query: 184 VEQYGSTWAET----NVIPKVLTMSREQNYLHRMTYLFCINVLSEVCGKDITTRVLLPTV 351
E ET ++P + + + N + I LS + GK+ T LLP
Sbjct: 296 GENLPIEDRETIIMNQILPYIKELVSDTNQHVKSALASVIMGLSTILGKENTIEHLLPLF 355
Query: 352 LSMADDSVANVRFNVAKTL 408
L+ D +VR N+ L
Sbjct: 356 LAQLKDECPDVRLNIISNL 374
Score = 34.7 bits (76), Expect = 0.20
Identities = 25/126 (19%), Positives = 54/126 (42%), Gaps = 1/126 (0%)
Frame = +1
Query: 133 DHVYAIREAATLNLKKLVEQYGSTWAETNVIPKVLTM-SREQNYLHRMTYLFCINVLSEV 309
D +R AA L + + ++ ++P ++ S EQ+ + + C+++ +
Sbjct: 162 DDTPMVRRAAASKLGEFAKVLELDSVKSEIVPLFTSLASDEQDSVRLLAVEACVSIAQLL 221
Query: 310 CGKDITTRVLLPTVLSMADDSVANVRFNVAKTLQKMAPFLDPAVIQPQVKPVLEKFER*S 489
D+ T V+ PT+ A+D VR+ VA ++ + P + + P + +
Sbjct: 222 SQDDLETLVM-PTLRQAAEDKSWRVRYMVADRFSELQKAMGPKITLNDLIPAFQNLLK-- 278
Query: 490 RCRCEI 507
C E+
Sbjct: 279 DCEAEV 284
Score = 29.5 bits (63), Expect = 7.4
Identities = 35/160 (21%), Positives = 61/160 (38%), Gaps = 4/160 (2%)
Frame = +1
Query: 7 LAEDTKWRVRLAIIEHMPLLAGQLGQEFFDEKLTGLCMSWLIDHVYAIREAATLNLKKLV 186
L D VR A + A L + ++ L S D ++R A +
Sbjct: 159 LCSDDTPMVRRAAASKLGEFAKVLELDSVKSEIVPLFTSLASDEQDSVRLLAVEACVSIA 218
Query: 187 EQYGSTWAETNVIPKVLTMSREQNYLHRMTYLFCINVLSEVCGKDITTRVLLPTVLSMAD 366
+ ET V+P + + ++++ R + L + G IT L+P ++
Sbjct: 219 QLLSQDDLETLVMPTLRQAAEDKSWRVRYMVADRFSELQKAMGPKITLNDLIPAFQNLLK 278
Query: 367 DSVANVRFNVA---KTLQKMAPFLD-PAVIQPQVKPVLEK 474
D A VR A K L + P D +I Q+ P +++
Sbjct: 279 DCEAEVRAAAAHKVKELGENLPIEDRETIIMNQILPYIKE 318
>BC027596-1|AAH27596.1| 667|Homo sapiens protein phosphatase 2
(formerly 2A), regulatory subunit A, beta isoform
protein.
Length = 667
Score = 244 bits (597), Expect = 1e-64
Identities = 111/158 (70%), Positives = 132/158 (83%)
Frame = +1
Query: 1 VELAEDTKWRVRLAIIEHMPLLAGQLGQEFFDEKLTGLCMSWLIDHVYAIREAATLNLKK 180
VELAED KWRVRLAIIE+MPLLAGQLG EFFDEKL LCM+WL+DHVYAIREAAT NL K
Sbjct: 421 VELAEDAKWRVRLAIIEYMPLLAGQLGVEFFDEKLNSLCMAWLVDHVYAIREAATNNLMK 480
Query: 181 LVEQYGSTWAETNVIPKVLTMSREQNYLHRMTYLFCINVLSEVCGKDITTRVLLPTVLSM 360
LV+++G+ WA+ ++PKVL M+ + NYLHRMT LFCIN LSE CG++ITT+ +LP VL M
Sbjct: 481 LVQKFGTEWAQNTIVPKVLVMANDPNYLHRMTTLFCINALSEACGQEITTKQMLPIVLKM 540
Query: 361 ADDSVANVRFNVAKTLQKMAPFLDPAVIQPQVKPVLEK 474
A D VANVRFNVAK+LQK+ P LD +Q +VKPVL+K
Sbjct: 541 AGDQVANVRFNVAKSLQKIGPILDTNALQGEVKPVLQK 578
Score = 47.6 bits (108), Expect = 3e-05
Identities = 37/139 (26%), Positives = 57/139 (41%), Gaps = 4/139 (2%)
Frame = +1
Query: 4 ELAEDTKWRVRLAIIEHMPLLAGQLGQEFFDEKLTGLCMSWLIDHVYAIREAATLNLKKL 183
+ AED WRVR + + L +G + L + L D +R AA +K+L
Sbjct: 262 QAAEDKSWRVRYMVADRFSELQKAMGPKITLNDLIPAFQNLLKDCEAEVRAAAAHKVKEL 321
Query: 184 VEQYGSTWAET----NVIPKVLTMSREQNYLHRMTYLFCINVLSEVCGKDITTRVLLPTV 351
E ET ++P + + + N + I LS + GK+ T LLP
Sbjct: 322 GENLPIEDRETIIMNQILPYIKELVSDTNQHVKSALASVIMGLSTILGKENTIEHLLPLF 381
Query: 352 LSMADDSVANVRFNVAKTL 408
L+ D +VR N+ L
Sbjct: 382 LAQLKDECPDVRLNIISNL 400
Score = 34.7 bits (76), Expect = 0.20
Identities = 25/126 (19%), Positives = 54/126 (42%), Gaps = 1/126 (0%)
Frame = +1
Query: 133 DHVYAIREAATLNLKKLVEQYGSTWAETNVIPKVLTM-SREQNYLHRMTYLFCINVLSEV 309
D +R AA L + + ++ ++P ++ S EQ+ + + C+++ +
Sbjct: 188 DDTPMVRRAAASKLGEFAKVLELDSVKSEIVPLFTSLASDEQDSVRLLAVEACVSIAQLL 247
Query: 310 CGKDITTRVLLPTVLSMADDSVANVRFNVAKTLQKMAPFLDPAVIQPQVKPVLEKFER*S 489
D+ T V+ PT+ A+D VR+ VA ++ + P + + P + +
Sbjct: 248 SQDDLETLVM-PTLRQAAEDKSWRVRYMVADRFSELQKAMGPKITLNDLIPAFQNLLK-- 304
Query: 490 RCRCEI 507
C E+
Sbjct: 305 DCEAEV 310
Score = 29.5 bits (63), Expect = 7.4
Identities = 35/160 (21%), Positives = 61/160 (38%), Gaps = 4/160 (2%)
Frame = +1
Query: 7 LAEDTKWRVRLAIIEHMPLLAGQLGQEFFDEKLTGLCMSWLIDHVYAIREAATLNLKKLV 186
L D VR A + A L + ++ L S D ++R A +
Sbjct: 185 LCSDDTPMVRRAAASKLGEFAKVLELDSVKSEIVPLFTSLASDEQDSVRLLAVEACVSIA 244
Query: 187 EQYGSTWAETNVIPKVLTMSREQNYLHRMTYLFCINVLSEVCGKDITTRVLLPTVLSMAD 366
+ ET V+P + + ++++ R + L + G IT L+P ++
Sbjct: 245 QLLSQDDLETLVMPTLRQAAEDKSWRVRYMVADRFSELQKAMGPKITLNDLIPAFQNLLK 304
Query: 367 DSVANVRFNVA---KTLQKMAPFLD-PAVIQPQVKPVLEK 474
D A VR A K L + P D +I Q+ P +++
Sbjct: 305 DCEAEVRAAAAHKVKELGENLPIEDRETIIMNQILPYIKE 344
>AF163473-1|AAG39644.1| 601|Homo sapiens protein phosphatase 2A
regulatory subunit A beta isoform protein.
Length = 601
Score = 244 bits (597), Expect = 1e-64
Identities = 111/158 (70%), Positives = 132/158 (83%)
Frame = +1
Query: 1 VELAEDTKWRVRLAIIEHMPLLAGQLGQEFFDEKLTGLCMSWLIDHVYAIREAATLNLKK 180
VELAED KWRVRLAIIE+MPLLAGQLG EFFDEKL LCM+WL+DHVYAIREAAT NL K
Sbjct: 421 VELAEDAKWRVRLAIIEYMPLLAGQLGVEFFDEKLNSLCMAWLVDHVYAIREAATNNLMK 480
Query: 181 LVEQYGSTWAETNVIPKVLTMSREQNYLHRMTYLFCINVLSEVCGKDITTRVLLPTVLSM 360
LV+++G+ WA+ ++PKVL M+ + NYLHRMT LFCIN LSE CG++ITT+ +LP VL M
Sbjct: 481 LVQKFGTEWAQNTIVPKVLVMANDPNYLHRMTTLFCINALSEACGQEITTKQMLPIVLKM 540
Query: 361 ADDSVANVRFNVAKTLQKMAPFLDPAVIQPQVKPVLEK 474
A D VANVRFNVAK+LQK+ P LD +Q +VKPVL+K
Sbjct: 541 AGDQVANVRFNVAKSLQKIGPILDTNALQGEVKPVLQK 578
Score = 47.6 bits (108), Expect = 3e-05
Identities = 37/139 (26%), Positives = 57/139 (41%), Gaps = 4/139 (2%)
Frame = +1
Query: 4 ELAEDTKWRVRLAIIEHMPLLAGQLGQEFFDEKLTGLCMSWLIDHVYAIREAATLNLKKL 183
+ AED WRVR + + L +G + L + L D +R AA +K+L
Sbjct: 262 QAAEDKSWRVRYMVADRFSELQKAMGPKITLNDLIPAFQNLLKDCEAEVRAAAAHKVKEL 321
Query: 184 VEQYGSTWAET----NVIPKVLTMSREQNYLHRMTYLFCINVLSEVCGKDITTRVLLPTV 351
E ET ++P + + + N + I LS + GK+ T LLP
Sbjct: 322 GENLPIEDRETIIMNQILPYIKELVSDTNQHVKSALASVIMGLSTILGKENTIEHLLPLF 381
Query: 352 LSMADDSVANVRFNVAKTL 408
L+ D +VR N+ L
Sbjct: 382 LAQLKDECPDVRLNIISNL 400
Score = 34.7 bits (76), Expect = 0.20
Identities = 25/126 (19%), Positives = 54/126 (42%), Gaps = 1/126 (0%)
Frame = +1
Query: 133 DHVYAIREAATLNLKKLVEQYGSTWAETNVIPKVLTM-SREQNYLHRMTYLFCINVLSEV 309
D +R AA L + + ++ ++P ++ S EQ+ + + C+++ +
Sbjct: 188 DDTPMVRRAAASKLGEFAKVLELDSVKSEIVPLFTSLASDEQDSVRLLAVEACVSIAQLL 247
Query: 310 CGKDITTRVLLPTVLSMADDSVANVRFNVAKTLQKMAPFLDPAVIQPQVKPVLEKFER*S 489
D+ T V+ PT+ A+D VR+ VA ++ + P + + P + +
Sbjct: 248 SQDDLETLVM-PTLRQAAEDKSWRVRYMVADRFSELQKAMGPKITLNDLIPAFQNLLK-- 304
Query: 490 RCRCEI 507
C E+
Sbjct: 305 DCEAEV 310
Score = 29.5 bits (63), Expect = 7.4
Identities = 35/160 (21%), Positives = 61/160 (38%), Gaps = 4/160 (2%)
Frame = +1
Query: 7 LAEDTKWRVRLAIIEHMPLLAGQLGQEFFDEKLTGLCMSWLIDHVYAIREAATLNLKKLV 186
L D VR A + A L + ++ L S D ++R A +
Sbjct: 185 LCSDDTPMVRRAAASKLGEFAKVLELDSVKSEIVPLFTSLASDEQDSVRLLAVEACVSIA 244
Query: 187 EQYGSTWAETNVIPKVLTMSREQNYLHRMTYLFCINVLSEVCGKDITTRVLLPTVLSMAD 366
+ ET V+P + + ++++ R + L + G IT L+P ++
Sbjct: 245 QLLSQDDLETLVMPTLRQAAEDKSWRVRYMVADRFSELQKAMGPKITLNDLIPAFQNLLK 304
Query: 367 DSVANVRFNVA---KTLQKMAPFLD-PAVIQPQVKPVLEK 474
D A VR A K L + P D +I Q+ P +++
Sbjct: 305 DCEAEVRAAAAHKVKELGENLPIEDRETIIMNQILPYIKE 344
>AF087438-1|AAC69624.1| 601|Homo sapiens protein phosphatase 2
subunit A isoform beta protein.
Length = 601
Score = 244 bits (597), Expect = 1e-64
Identities = 111/158 (70%), Positives = 132/158 (83%)
Frame = +1
Query: 1 VELAEDTKWRVRLAIIEHMPLLAGQLGQEFFDEKLTGLCMSWLIDHVYAIREAATLNLKK 180
VELAED KWRVRLAIIE+MPLLAGQLG EFFDEKL LCM+WL+DHVYAIREAAT NL K
Sbjct: 421 VELAEDAKWRVRLAIIEYMPLLAGQLGVEFFDEKLNSLCMAWLVDHVYAIREAATNNLMK 480
Query: 181 LVEQYGSTWAETNVIPKVLTMSREQNYLHRMTYLFCINVLSEVCGKDITTRVLLPTVLSM 360
LV+++G+ WA+ ++PKVL M+ + NYLHRMT LFCIN LSE CG++ITT+ +LP VL M
Sbjct: 481 LVQKFGTEWAQNTIVPKVLVMANDPNYLHRMTTLFCINALSEACGQEITTKQMLPIVLKM 540
Query: 361 ADDSVANVRFNVAKTLQKMAPFLDPAVIQPQVKPVLEK 474
A D VANVRFNVAK+LQK+ P LD +Q +VKPVL+K
Sbjct: 541 AGDQVANVRFNVAKSLQKIGPILDTNALQGEVKPVLQK 578
Score = 47.6 bits (108), Expect = 3e-05
Identities = 37/139 (26%), Positives = 57/139 (41%), Gaps = 4/139 (2%)
Frame = +1
Query: 4 ELAEDTKWRVRLAIIEHMPLLAGQLGQEFFDEKLTGLCMSWLIDHVYAIREAATLNLKKL 183
+ AED WRVR + + L +G + L + L D +R AA +K+L
Sbjct: 262 QAAEDKSWRVRYMVADRFSELQKAMGPKITLNDLIPAFQNLLKDCEAEVRAAAAHKVKEL 321
Query: 184 VEQYGSTWAET----NVIPKVLTMSREQNYLHRMTYLFCINVLSEVCGKDITTRVLLPTV 351
E ET ++P + + + N + I LS + GK+ T LLP
Sbjct: 322 GENLPIEDRETIIMNQILPYIKELVSDTNQHVKSALASVIMGLSTILGKENTIEHLLPLF 381
Query: 352 LSMADDSVANVRFNVAKTL 408
L+ D +VR N+ L
Sbjct: 382 LAQLKDECPDVRLNIISNL 400
Score = 34.7 bits (76), Expect = 0.20
Identities = 25/126 (19%), Positives = 54/126 (42%), Gaps = 1/126 (0%)
Frame = +1
Query: 133 DHVYAIREAATLNLKKLVEQYGSTWAETNVIPKVLTM-SREQNYLHRMTYLFCINVLSEV 309
D +R AA L + + ++ ++P ++ S EQ+ + + C+++ +
Sbjct: 188 DDTPMVRRAAASKLGEFAKVLELDSVKSEIVPLFTSLASDEQDSVRLLAVEACVSIAQLL 247
Query: 310 CGKDITTRVLLPTVLSMADDSVANVRFNVAKTLQKMAPFLDPAVIQPQVKPVLEKFER*S 489
D+ T V+ PT+ A+D VR+ VA ++ + P + + P + +
Sbjct: 248 SQDDLETLVM-PTLRQAAEDKSWRVRYMVADRFSELQKAMGPKITLNDLIPAFQNLLK-- 304
Query: 490 RCRCEI 507
C E+
Sbjct: 305 DCEAEV 310
Score = 29.5 bits (63), Expect = 7.4
Identities = 35/160 (21%), Positives = 61/160 (38%), Gaps = 4/160 (2%)
Frame = +1
Query: 7 LAEDTKWRVRLAIIEHMPLLAGQLGQEFFDEKLTGLCMSWLIDHVYAIREAATLNLKKLV 186
L D VR A + A L + ++ L S D ++R A +
Sbjct: 185 LCSDDTPMVRRAAASKLGEFAKVLELDSVKSEIVPLFTSLASDEQDSVRLLAVEACVSIA 244
Query: 187 EQYGSTWAETNVIPKVLTMSREQNYLHRMTYLFCINVLSEVCGKDITTRVLLPTVLSMAD 366
+ ET V+P + + ++++ R + L + G IT L+P ++
Sbjct: 245 QLLSQDDLETLVMPTLRQAAEDKSWRVRYMVADRFSELQKAMGPKITLNDLIPAFQNLLK 304
Query: 367 DSVANVRFNVA---KTLQKMAPFLD-PAVIQPQVKPVLEK 474
D A VR A K L + P D +I Q+ P +++
Sbjct: 305 DCEAEVRAAAAHKVKELGENLPIEDRETIIMNQILPYIKE 344
>AF083439-1|AAC63525.1| 601|Homo sapiens protein phosphatase 2A
regulatory subunit A, beta isoform protein.
Length = 601
Score = 244 bits (597), Expect = 1e-64
Identities = 111/158 (70%), Positives = 132/158 (83%)
Frame = +1
Query: 1 VELAEDTKWRVRLAIIEHMPLLAGQLGQEFFDEKLTGLCMSWLIDHVYAIREAATLNLKK 180
VELAED KWRVRLAIIE+MPLLAGQLG EFFDEKL LCM+WL+DHVYAIREAAT NL K
Sbjct: 421 VELAEDAKWRVRLAIIEYMPLLAGQLGVEFFDEKLNSLCMAWLVDHVYAIREAATNNLMK 480
Query: 181 LVEQYGSTWAETNVIPKVLTMSREQNYLHRMTYLFCINVLSEVCGKDITTRVLLPTVLSM 360
LV+++G+ WA+ ++PKVL M+ + NYLHRMT LFCIN LSE CG++ITT+ +LP VL M
Sbjct: 481 LVQKFGTEWAQNTIVPKVLVMANDPNYLHRMTTLFCINALSEACGQEITTKQMLPIVLKM 540
Query: 361 ADDSVANVRFNVAKTLQKMAPFLDPAVIQPQVKPVLEK 474
A D VANVRFNVAK+LQK+ P LD +Q +VKPVL+K
Sbjct: 541 AGDQVANVRFNVAKSLQKIGPILDTNALQGEVKPVLQK 578
Score = 47.6 bits (108), Expect = 3e-05
Identities = 37/139 (26%), Positives = 57/139 (41%), Gaps = 4/139 (2%)
Frame = +1
Query: 4 ELAEDTKWRVRLAIIEHMPLLAGQLGQEFFDEKLTGLCMSWLIDHVYAIREAATLNLKKL 183
+ AED WRVR + + L +G + L + L D +R AA +K+L
Sbjct: 262 QAAEDKSWRVRYMVADRFSELQKAMGPKITLNDLIPAFQNLLKDCEAEVRAAAAHKVKEL 321
Query: 184 VEQYGSTWAET----NVIPKVLTMSREQNYLHRMTYLFCINVLSEVCGKDITTRVLLPTV 351
E ET ++P + + + N + I LS + GK+ T LLP
Sbjct: 322 GENLPIEDRETIIMNQILPYIKELVSDTNQHVKSALASVIMGLSTILGKENTIEHLLPLF 381
Query: 352 LSMADDSVANVRFNVAKTL 408
L+ D +VR N+ L
Sbjct: 382 LAQLKDECPDVRLNIISNL 400
Score = 34.7 bits (76), Expect = 0.20
Identities = 25/126 (19%), Positives = 54/126 (42%), Gaps = 1/126 (0%)
Frame = +1
Query: 133 DHVYAIREAATLNLKKLVEQYGSTWAETNVIPKVLTM-SREQNYLHRMTYLFCINVLSEV 309
D +R AA L + + ++ ++P ++ S EQ+ + + C+++ +
Sbjct: 188 DDTPMVRRAAASKLGEFAKVLELDSVKSEIVPLFTSLASDEQDSVRLLAVEACVSIAQLL 247
Query: 310 CGKDITTRVLLPTVLSMADDSVANVRFNVAKTLQKMAPFLDPAVIQPQVKPVLEKFER*S 489
D+ T V+ PT+ A+D VR+ VA ++ + P + + P + +
Sbjct: 248 SQDDLETLVM-PTLRQAAEDKSWRVRYMVADRFSELQKAMGPKITLNDLIPAFQNLLK-- 304
Query: 490 RCRCEI 507
C E+
Sbjct: 305 DCEAEV 310
Score = 29.5 bits (63), Expect = 7.4
Identities = 35/160 (21%), Positives = 61/160 (38%), Gaps = 4/160 (2%)
Frame = +1
Query: 7 LAEDTKWRVRLAIIEHMPLLAGQLGQEFFDEKLTGLCMSWLIDHVYAIREAATLNLKKLV 186
L D VR A + A L + ++ L S D ++R A +
Sbjct: 185 LCSDDTPMVRRAAASKLGEFAKVLELDSVKSEIVPLFTSLASDEQDSVRLLAVEACVSIA 244
Query: 187 EQYGSTWAETNVIPKVLTMSREQNYLHRMTYLFCINVLSEVCGKDITTRVLLPTVLSMAD 366
+ ET V+P + + ++++ R + L + G IT L+P ++
Sbjct: 245 QLLSQDDLETLVMPTLRQAAEDKSWRVRYMVADRFSELQKAMGPKITLNDLIPAFQNLLK 304
Query: 367 DSVANVRFNVA---KTLQKMAPFLD-PAVIQPQVKPVLEK 474
D A VR A K L + P D +I Q+ P +++
Sbjct: 305 DCEAEVRAAAAHKVKELGENLPIEDRETIIMNQILPYIKE 344
>BC060829-1|AAH60829.1| 933|Homo sapiens protein phosphatase 4,
regulatory subunit 1 protein.
Length = 933
Score = 37.9 bits (84), Expect = 0.021
Identities = 35/136 (25%), Positives = 61/136 (44%), Gaps = 6/136 (4%)
Frame = +1
Query: 25 WRVRLAIIEHMPLLAGQLGQEFFDEKLTGLCMSWLIDHVYAIR----EAATLNLKKLVEQ 192
WR R + E + LL + L + ++ D V ++R + + +KKL
Sbjct: 739 WRFRAELAEQLILLLELYSPRDVYDYLRPIALNLCADKVSSVRWISYKLVSEMVKKLHAA 798
Query: 193 YGSTWAETNVIPKVLTMSREQNYLHRMTYLF-CINVLSEVC-GKDITTRVLLPTVLSMAD 366
T+ + V R + R ++F C V+ + C D L+P +L++A+
Sbjct: 799 TPPTFGVDLINELVENFGRCPKWSGRQAFVFVCQTVIEDDCLPMDQFAVHLMPHLLTLAN 858
Query: 367 DSVANVRFNVAKTLQK 414
D V NVR +AKTL++
Sbjct: 859 DRVPNVRVLLAKTLRQ 874
Score = 32.7 bits (71), Expect = 0.79
Identities = 33/130 (25%), Positives = 59/130 (45%), Gaps = 9/130 (6%)
Frame = +1
Query: 7 LAEDTKWRVRLAIIEHMPLLAGQLGQE------FFDEKLTGLCMSWLIDHVYAIREAATL 168
LA+D++ VR ++E +P +A + F + L + + +L D +R+ +
Sbjct: 77 LADDSEPTVRAELMEQVPHIALFCQENRPSIPYAFSKFLLPIVVRYLADQNNQVRKTSQA 136
Query: 169 NLKKLVEQ--YGSTWAETNVIPKVLTMSREQNYLHRMTYLFCINV-LSEVCGKDITTRVL 339
L L+EQ ET V P ++ ++ + T I ++ + GKDIT R++
Sbjct: 137 ALLALLEQELIERFDVETKVCPVLIELTAPDSNDDVKTEAVAIMCKMAPMVGKDITERLI 196
Query: 340 LPTVLSMADD 369
LP M D
Sbjct: 197 LPRFCEMCCD 206
>AF200478-1|AAL78298.1| 950|Homo sapiens protein serine/threonine
phosphatase 4 subunit PP4Rmeg protein.
Length = 950
Score = 37.9 bits (84), Expect = 0.021
Identities = 35/136 (25%), Positives = 61/136 (44%), Gaps = 6/136 (4%)
Frame = +1
Query: 25 WRVRLAIIEHMPLLAGQLGQEFFDEKLTGLCMSWLIDHVYAIR----EAATLNLKKLVEQ 192
WR R + E + LL + L + ++ D V ++R + + +KKL
Sbjct: 756 WRFRAELAEQLILLLELYSPRDVYDYLRPIALNLCADKVSSVRWISYKLVSEMVKKLHAA 815
Query: 193 YGSTWAETNVIPKVLTMSREQNYLHRMTYLF-CINVLSEVC-GKDITTRVLLPTVLSMAD 366
T+ + V R + R ++F C V+ + C D L+P +L++A+
Sbjct: 816 TPPTFGVDLINELVENFGRCPKWSGRQAFVFVCQTVIEDDCLPMDQFAVHLMPHLLTLAN 875
Query: 367 DSVANVRFNVAKTLQK 414
D V NVR +AKTL++
Sbjct: 876 DRVPNVRVLLAKTLRQ 891
Score = 32.7 bits (71), Expect = 0.79
Identities = 33/130 (25%), Positives = 59/130 (45%), Gaps = 9/130 (6%)
Frame = +1
Query: 7 LAEDTKWRVRLAIIEHMPLLAGQLGQE------FFDEKLTGLCMSWLIDHVYAIREAATL 168
LA+D++ VR ++E +P +A + F + L + + +L D +R+ +
Sbjct: 94 LADDSEPTVRAELMEQVPHIALFCQENRPSIPYAFSKFLLPIVVRYLADQNNQVRKTSQA 153
Query: 169 NLKKLVEQ--YGSTWAETNVIPKVLTMSREQNYLHRMTYLFCINV-LSEVCGKDITTRVL 339
L L+EQ ET V P ++ ++ + T I ++ + GKDIT R++
Sbjct: 154 ALLALLEQELIERFDVETKVCPVLIELTAPDSNDDVKTEAVAIMCKMAPMVGKDITERLI 213
Query: 340 LPTVLSMADD 369
LP M D
Sbjct: 214 LPRFCEMCCD 223
>AF111106-1|AAD09818.1| 933|Homo sapiens protein serine/threonine
phosphatase 4 regulatory subunit 1 protein.
Length = 933
Score = 37.9 bits (84), Expect = 0.021
Identities = 35/136 (25%), Positives = 61/136 (44%), Gaps = 6/136 (4%)
Frame = +1
Query: 25 WRVRLAIIEHMPLLAGQLGQEFFDEKLTGLCMSWLIDHVYAIR----EAATLNLKKLVEQ 192
WR R + E + LL + L + ++ D V ++R + + +KKL
Sbjct: 739 WRFRAELAEQLILLLELYSPRDVYDYLRPIALNLCADKVSSVRWISYKLVSEMVKKLHAA 798
Query: 193 YGSTWAETNVIPKVLTMSREQNYLHRMTYLF-CINVLSEVC-GKDITTRVLLPTVLSMAD 366
T+ + V R + R ++F C V+ + C D L+P +L++A+
Sbjct: 799 TPPTFGVDLINELVENFGRCPKWSGRQAFVFVCQTVIEDDCLPMDQFAVHLMPHLLTLAN 858
Query: 367 DSVANVRFNVAKTLQK 414
D V NVR +AKTL++
Sbjct: 859 DRVPNVRVLLAKTLRQ 874
Score = 32.7 bits (71), Expect = 0.79
Identities = 33/130 (25%), Positives = 59/130 (45%), Gaps = 9/130 (6%)
Frame = +1
Query: 7 LAEDTKWRVRLAIIEHMPLLAGQLGQE------FFDEKLTGLCMSWLIDHVYAIREAATL 168
LA+D++ VR ++E +P +A + F + L + + +L D +R+ +
Sbjct: 77 LADDSEPTVRAELMEQVPHIALFCQENRPSIPYAFSKFLLPIVVRYLADQNNQVRKTSQA 136
Query: 169 NLKKLVEQ--YGSTWAETNVIPKVLTMSREQNYLHRMTYLFCINV-LSEVCGKDITTRVL 339
L L+EQ ET V P ++ ++ + T I ++ + GKDIT R++
Sbjct: 137 ALLALLEQELIERFDVETKVCPVLIELTAPDSNDDVKTEAVAIMCKMAPMVGKDITERLI 196
Query: 340 LPTVLSMADD 369
LP M D
Sbjct: 197 LPRFCEMCCD 206
>BC068491-1|AAH68491.1| 873|Homo sapiens KIAA1622 protein.
Length = 873
Score = 37.1 bits (82), Expect = 0.037
Identities = 20/102 (19%), Positives = 49/102 (48%)
Frame = +1
Query: 172 LKKLVEQYGSTWAETNVIPKVLTMSREQNYLHRMTYLFCINVLSEVCGKDITTRVLLPTV 351
L KL ++ + + ++P V ++ ++ Y R + +++ G ++T V+LP +
Sbjct: 197 LGKLTNKFDAHTIKREILPLVKSLCQDVEYEVRSCMCRQLENIAQGIGTELTKSVVLPEL 256
Query: 352 LSMADDSVANVRFNVAKTLQKMAPFLDPAVIQPQVKPVLEKF 477
+ ++ D ++VR +TL + D + P+++ F
Sbjct: 257 IELSRDEGSSVRLAAFETLVNLLDIFDTDDRSQTILPLVKSF 298
Score = 33.5 bits (73), Expect = 0.45
Identities = 22/113 (19%), Positives = 49/113 (43%)
Frame = +1
Query: 34 RLAIIEHMPLLAGQLGQEFFDEKLTGLCMSWLIDHVYAIREAATLNLKKLVEQYGSTWAE 213
RL + + L + ++ L S D Y +R L+ + + G+ +
Sbjct: 190 RLVSCKILGKLTNKFDAHTIKREILPLVKSLCQDVEYEVRSCMCRQLENIAQGIGTELTK 249
Query: 214 TNVIPKVLTMSREQNYLHRMTYLFCINVLSEVCGKDITTRVLLPTVLSMADDS 372
+ V+P+++ +SR++ R+ + L ++ D ++ +LP V S + S
Sbjct: 250 SVVLPELIELSRDEGSSVRLAAFETLVNLLDIFDTDDRSQTILPLVKSFCEKS 302
>AB046842-1|BAB13448.1| 892|Homo sapiens KIAA1622 protein protein.
Length = 892
Score = 37.1 bits (82), Expect = 0.037
Identities = 20/102 (19%), Positives = 49/102 (48%)
Frame = +1
Query: 172 LKKLVEQYGSTWAETNVIPKVLTMSREQNYLHRMTYLFCINVLSEVCGKDITTRVLLPTV 351
L KL ++ + + ++P V ++ ++ Y R + +++ G ++T V+LP +
Sbjct: 216 LGKLTNKFDAHTIKREILPLVKSLCQDVEYEVRSCMCRQLENIAQGIGTELTKSVVLPEL 275
Query: 352 LSMADDSVANVRFNVAKTLQKMAPFLDPAVIQPQVKPVLEKF 477
+ ++ D ++VR +TL + D + P+++ F
Sbjct: 276 IELSRDEGSSVRLAAFETLVNLLDIFDTDDRSQTILPLVKSF 317
Score = 33.5 bits (73), Expect = 0.45
Identities = 22/113 (19%), Positives = 49/113 (43%)
Frame = +1
Query: 34 RLAIIEHMPLLAGQLGQEFFDEKLTGLCMSWLIDHVYAIREAATLNLKKLVEQYGSTWAE 213
RL + + L + ++ L S D Y +R L+ + + G+ +
Sbjct: 209 RLVSCKILGKLTNKFDAHTIKREILPLVKSLCQDVEYEVRSCMCRQLENIAQGIGTELTK 268
Query: 214 TNVIPKVLTMSREQNYLHRMTYLFCINVLSEVCGKDITTRVLLPTVLSMADDS 372
+ V+P+++ +SR++ R+ + L ++ D ++ +LP V S + S
Sbjct: 269 SVVLPELIELSRDEGSSVRLAAFETLVNLLDIFDTDDRSQTILPLVKSFCEKS 321
>U79267-1|AAB50211.1| 173|Homo sapiens unknown protein.
Length = 173
Score = 32.3 bits (70), Expect = 1.0
Identities = 25/83 (30%), Positives = 41/83 (49%), Gaps = 2/83 (2%)
Frame = +1
Query: 172 LKKLVEQYGSTWAETNVIPKVLTMSREQNYLHRMTYLF-CINVLSEVC-GKDITTRVLLP 345
+KKL T+ + V R + R ++F C V+ + C D L+P
Sbjct: 32 VKKLHAATPPTFGVDLINELVENFGRCPKWSGRQAFVFVCQTVIEDDCLPMDQFAVHLMP 91
Query: 346 TVLSMADDSVANVRFNVAKTLQK 414
+L++A+D V NVR +AKTL++
Sbjct: 92 HLLTLANDRVPNVRVLLAKTLRQ 114
>BC089393-1|AAH89393.1| 209|Homo sapiens tripartite
motif-containing 61 protein.
Length = 209
Score = 30.7 bits (66), Expect = 3.2
Identities = 16/41 (39%), Positives = 27/41 (65%), Gaps = 1/41 (2%)
Frame = +1
Query: 139 VYAIREAATLNLKKLVEQYGSTWAE-TNVIPKVLTMSREQN 258
V+ I++AA+ + KKL E+Y + W E +I KV+TM ++
Sbjct: 130 VWPIKKAASYHRKKL-EEYNAPWKERVELIEKVITMQTRKS 169
>BC032762-1|AAH32762.1| 571|Homo sapiens OPTN protein protein.
Length = 571
Score = 29.5 bits (63), Expect = 7.4
Identities = 27/109 (24%), Positives = 48/109 (44%), Gaps = 2/109 (1%)
Frame = +1
Query: 160 ATLNLKKLVEQYGSTWAETNVIPKVLTMSREQNYLHRMTYLFCINVLSEVCGKDITTRVL 339
A L K+L E+ + + + IP L +E Y ++ L ++LSE+ + T
Sbjct: 317 AELMKKRLQEKCQALERKNSAIPSELNEKQELVYTNKKLELQVESMLSEIKMEQAKTEDE 376
Query: 340 LP--TVLSMADDSVANVRFNVAKTLQKMAPFLDPAVIQPQVKPVLEKFE 480
TVL M + + N KT++++ V + +K + EK E
Sbjct: 377 KSKLTVLQMTHNKLLQEHNNALKTIEELTRKESEKVDRAVLKELSEKLE 425
>BC013876-1|AAH13876.1| 577|Homo sapiens optineurin protein.
Length = 577
Score = 29.5 bits (63), Expect = 7.4
Identities = 27/109 (24%), Positives = 48/109 (44%), Gaps = 2/109 (1%)
Frame = +1
Query: 160 ATLNLKKLVEQYGSTWAETNVIPKVLTMSREQNYLHRMTYLFCINVLSEVCGKDITTRVL 339
A L K+L E+ + + + IP L +E Y ++ L ++LSE+ + T
Sbjct: 323 AELMKKRLQEKCQALERKNSAIPSELNEKQELVYTNKKLELQVESMLSEIKMEQAKTEDE 382
Query: 340 LP--TVLSMADDSVANVRFNVAKTLQKMAPFLDPAVIQPQVKPVLEKFE 480
TVL M + + N KT++++ V + +K + EK E
Sbjct: 383 KSKLTVLQMTHNKLLQEHNNALKTIEELTRKESEKVDRAVLKELSEKLE 431
>AL355355-6|CAI16550.1| 571|Homo sapiens optineurin protein.
Length = 571
Score = 29.5 bits (63), Expect = 7.4
Identities = 27/109 (24%), Positives = 48/109 (44%), Gaps = 2/109 (1%)
Frame = +1
Query: 160 ATLNLKKLVEQYGSTWAETNVIPKVLTMSREQNYLHRMTYLFCINVLSEVCGKDITTRVL 339
A L K+L E+ + + + IP L +E Y ++ L ++LSE+ + T
Sbjct: 317 AELMKKRLQEKCQALERKNSAIPSELNEKQELVYTNKKLELQVESMLSEIKMEQAKTEDE 376
Query: 340 LP--TVLSMADDSVANVRFNVAKTLQKMAPFLDPAVIQPQVKPVLEKFE 480
TVL M + + N KT++++ V + +K + EK E
Sbjct: 377 KSKLTVLQMTHNKLLQEHNNALKTIEELTRKESEKVDRAVLKELSEKLE 425
>AL355355-5|CAI16549.1| 577|Homo sapiens optineurin protein.
Length = 577
Score = 29.5 bits (63), Expect = 7.4
Identities = 27/109 (24%), Positives = 48/109 (44%), Gaps = 2/109 (1%)
Frame = +1
Query: 160 ATLNLKKLVEQYGSTWAETNVIPKVLTMSREQNYLHRMTYLFCINVLSEVCGKDITTRVL 339
A L K+L E+ + + + IP L +E Y ++ L ++LSE+ + T
Sbjct: 323 AELMKKRLQEKCQALERKNSAIPSELNEKQELVYTNKKLELQVESMLSEIKMEQAKTEDE 382
Query: 340 LP--TVLSMADDSVANVRFNVAKTLQKMAPFLDPAVIQPQVKPVLEKFE 480
TVL M + + N KT++++ V + +K + EK E
Sbjct: 383 KSKLTVLQMTHNKLLQEHNNALKTIEELTRKESEKVDRAVLKELSEKLE 431
>AF420373-1|AAL76329.1| 577|Homo sapiens optineurin isoform 3
protein.
Length = 577
Score = 29.5 bits (63), Expect = 7.4
Identities = 27/109 (24%), Positives = 48/109 (44%), Gaps = 2/109 (1%)
Frame = +1
Query: 160 ATLNLKKLVEQYGSTWAETNVIPKVLTMSREQNYLHRMTYLFCINVLSEVCGKDITTRVL 339
A L K+L E+ + + + IP L +E Y ++ L ++LSE+ + T
Sbjct: 323 AELMKKRLQEKCQALERKNSAIPSELNEKQELVYTNKKLELQVESMLSEIKMEQAKTEDE 382
Query: 340 LP--TVLSMADDSVANVRFNVAKTLQKMAPFLDPAVIQPQVKPVLEKFE 480
TVL M + + N KT++++ V + +K + EK E
Sbjct: 383 KSKLTVLQMTHNKLLQEHNNALKTIEELTRKESEKVDRAVLKELSEKLE 431
>AF420372-1|AAL76328.1| 577|Homo sapiens optineurin isoform 2
protein.
Length = 577
Score = 29.5 bits (63), Expect = 7.4
Identities = 27/109 (24%), Positives = 48/109 (44%), Gaps = 2/109 (1%)
Frame = +1
Query: 160 ATLNLKKLVEQYGSTWAETNVIPKVLTMSREQNYLHRMTYLFCINVLSEVCGKDITTRVL 339
A L K+L E+ + + + IP L +E Y ++ L ++LSE+ + T
Sbjct: 323 AELMKKRLQEKCQALERKNSAIPSELNEKQELVYTNKKLELQVESMLSEIKMEQAKTEDE 382
Query: 340 LP--TVLSMADDSVANVRFNVAKTLQKMAPFLDPAVIQPQVKPVLEKFE 480
TVL M + + N KT++++ V + +K + EK E
Sbjct: 383 KSKLTVLQMTHNKLLQEHNNALKTIEELTRKESEKVDRAVLKELSEKLE 431
>AF420371-1|AAL76327.1| 577|Homo sapiens optineurin isoform 1
protein.
Length = 577
Score = 29.5 bits (63), Expect = 7.4
Identities = 27/109 (24%), Positives = 48/109 (44%), Gaps = 2/109 (1%)
Frame = +1
Query: 160 ATLNLKKLVEQYGSTWAETNVIPKVLTMSREQNYLHRMTYLFCINVLSEVCGKDITTRVL 339
A L K+L E+ + + + IP L +E Y ++ L ++LSE+ + T
Sbjct: 323 AELMKKRLQEKCQALERKNSAIPSELNEKQELVYTNKKLELQVESMLSEIKMEQAKTEDE 382
Query: 340 LP--TVLSMADDSVANVRFNVAKTLQKMAPFLDPAVIQPQVKPVLEKFE 480
TVL M + + N KT++++ V + +K + EK E
Sbjct: 383 KSKLTVLQMTHNKLLQEHNNALKTIEELTRKESEKVDRAVLKELSEKLE 431
Database: human
Posted date: Oct 23, 2007 1:18 PM
Number of letters in database: 76,859,062
Number of sequences in database: 237,096
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 78,106,456
Number of Sequences: 237096
Number of extensions: 1547597
Number of successful extensions: 3156
Number of sequences better than 10.0: 24
Number of HSP's better than 10.0 without gapping: 3014
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 3146
length of database: 76,859,062
effective HSP length: 85
effective length of database: 56,705,902
effective search space used: 4933413474
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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