Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= I10A02NGRL0006_C01
(298 letters)
Database: uniref50
1,657,284 sequences; 575,637,011 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
UniRef50_A1XG92 Cluster: Putative cathepsin B-like like proteina... 59 2e-08
UniRef50_Q70EW7 Cluster: Cathepsin B-like proteinase precursor; ... 45 3e-04
UniRef50_P07858 Cluster: Cathepsin B precursor (EC 3.4.22.1) (Ca... 44 9e-04
UniRef50_Q86GF5 Cluster: Cathepsin B; n=1; Pandalus borealis|Rep... 42 0.003
UniRef50_Q86GZ6 Cluster: Midgut cysteine proteinase 1; n=1; Rhip... 39 0.019
UniRef50_Q5MBV5 Cluster: Parcxpwnx02; n=3; Neoptera|Rep: Parcxpw... 38 0.044
UniRef50_A1XG93 Cluster: Putative cathepsin B-like proteinase; n... 38 0.059
UniRef50_Q4RKR3 Cluster: Chromosome 5 SCAF15026, whole genome sh... 35 0.31
UniRef50_A7LM75 Cluster: Cathepsin B preproprotein precursor; n=... 34 0.55
UniRef50_Q5VJM8 Cluster: Cathepsin B-like cysteine protease; n=2... 34 0.72
UniRef50_Q8MNY7 Cluster: Cathepsin B-like protease precursor; n=... 32 2.9
UniRef50_Q6FU29 Cluster: Candida glabrata strain CBS138 chromoso... 31 6.7
UniRef50_Q4T0Z0 Cluster: Chromosome 12 SCAF10787, whole genome s... 30 8.9
UniRef50_Q8T659 Cluster: Cathepsin B; n=1; Apriona germari|Rep: ... 30 8.9
UniRef50_Q7QWK3 Cluster: GLP_762_51859_50456; n=1; Giardia lambl... 30 8.9
UniRef50_Q6L8N8 Cluster: Cathepsin B-S precursor; n=15; Aphidoid... 30 8.9
UniRef50_Q8NIS9 Cluster: Putative uncharacterized protein B23E9.... 30 8.9
UniRef50_Q7RXE3 Cluster: Predicted protein; n=1; Neurospora cras... 30 8.9
UniRef50_Q4WAY3 Cluster: Polyketide synthase, putative; n=1; Asp... 30 8.9
>UniRef50_A1XG92 Cluster: Putative cathepsin B-like like proteinase;
n=1; Tenebrio molitor|Rep: Putative cathepsin B-like
like proteinase - Tenebrio molitor (Yellow mealworm)
Length = 301
Score = 58.8 bits (136), Expect = 2e-08
Identities = 27/55 (49%), Positives = 32/55 (58%)
Frame = +2
Query: 128 VALACILAVVASDLPHPLSDAFXNLINKKQNTWKAGRNFPTHTPFAHITIXMGAL 292
V LA + HPLSD F N IN KQ TWKAGRNF +TP +H+ +G L
Sbjct: 9 VVLASVALSYGGVKLHPLSDEFINEINSKQTTWKAGRNFDVNTPISHVRRLLGVL 63
>UniRef50_Q70EW7 Cluster: Cathepsin B-like proteinase precursor;
n=1; Diabrotica virgifera virgifera|Rep: Cathepsin
B-like proteinase precursor - Diabrotica virgifera
virgifera (western corn rootworm)
Length = 331
Score = 45.2 bits (102), Expect = 3e-04
Identities = 22/59 (37%), Positives = 31/59 (52%)
Frame = +2
Query: 119 ALYVALACILAVVASDLPHPLSDAFXNLINKKQNTWKAGRNFPTHTPFAHITIXMGALK 295
A + L + + P+PLS+ F N IN KQ+TW AG+NF + I +GA K
Sbjct: 4 AFIITLLLPIVLSYKGSPNPLSNDFINYINSKQSTWVAGKNFDENLSIQEIKNLLGAKK 62
>UniRef50_P07858 Cluster: Cathepsin B precursor (EC 3.4.22.1)
(Cathepsin B1) (APP secretase) (APPS) [Contains:
Cathepsin B light chain; Cathepsin B heavy chain]; n=85;
Eukaryota|Rep: Cathepsin B precursor (EC 3.4.22.1)
(Cathepsin B1) (APP secretase) (APPS) [Contains:
Cathepsin B light chain; Cathepsin B heavy chain] - Homo
sapiens (Human)
Length = 339
Score = 43.6 bits (98), Expect = 9e-04
Identities = 20/44 (45%), Positives = 27/44 (61%), Gaps = 3/44 (6%)
Frame = +2
Query: 122 LYVALACILAVV-ASDLP--HPLSDAFXNLINKKQNTWKAGRNF 244
L+ +L C+L + A P HPLSD N +NK+ TW+AG NF
Sbjct: 4 LWASLCCLLVLANARSRPSFHPLSDELVNYVNKRNTTWQAGHNF 47
>UniRef50_Q86GF5 Cluster: Cathepsin B; n=1; Pandalus borealis|Rep:
Cathepsin B - Pandalus borealis (Northern red shrimp)
Length = 328
Score = 41.9 bits (94), Expect = 0.003
Identities = 21/39 (53%), Positives = 22/39 (56%)
Frame = +2
Query: 128 VALACILAVVASDLPHPLSDAFXNLINKKQNTWKAGRNF 244
V L L AS PLSD F L+ KQ TWKAGRNF
Sbjct: 3 VLLLLALVAAASAELDPLSDEFLELLQSKQMTWKAGRNF 41
>UniRef50_Q86GZ6 Cluster: Midgut cysteine proteinase 1; n=1;
Rhipicephalus appendiculatus|Rep: Midgut cysteine
proteinase 1 - Rhipicephalus appendiculatus (Brown ear
tick)
Length = 332
Score = 39.1 bits (87), Expect = 0.019
Identities = 20/43 (46%), Positives = 24/43 (55%)
Frame = +2
Query: 116 CALYVALACILAVVASDLPHPLSDAFXNLINKKQNTWKAGRNF 244
C L+V A +V S + PLS+ N IN TWKAGRNF
Sbjct: 7 CVLFVVAAQGRLMVPSSV-EPLSEEMINFINSINTTWKAGRNF 48
>UniRef50_Q5MBV5 Cluster: Parcxpwnx02; n=3; Neoptera|Rep:
Parcxpwnx02 - Periplaneta americana (American cockroach)
Length = 343
Score = 37.9 bits (84), Expect = 0.044
Identities = 20/42 (47%), Positives = 21/42 (50%)
Frame = +2
Query: 161 SDLPHPLSDAFXNLINKKQNTWKAGRNFPTHTPFAHITIXMG 286
S L PLSD F + IN TWKA RNF P I MG
Sbjct: 30 SVLVDPLSDDFIDHINSLNTTWKAHRNFGNDIPLREIKKLMG 71
>UniRef50_A1XG93 Cluster: Putative cathepsin B-like proteinase; n=4;
Tenebrionidae|Rep: Putative cathepsin B-like proteinase
- Tenebrio molitor (Yellow mealworm)
Length = 321
Score = 37.5 bits (83), Expect = 0.059
Identities = 17/47 (36%), Positives = 31/47 (65%), Gaps = 2/47 (4%)
Frame = +2
Query: 122 LYVALACILAVVASDLPH--PLSDAFXNLINKKQNTWKAGRNFPTHT 256
++++ ++AV+++ L LS F + IN+ Q++W AGRNFP +T
Sbjct: 3 IFLSFVVLVAVLSASLAEIDVLSSEFIDSINRIQSSWVAGRNFPENT 49
>UniRef50_Q4RKR3 Cluster: Chromosome 5 SCAF15026, whole genome
shotgun sequence; n=2; Tetraodontidae|Rep: Chromosome 5
SCAF15026, whole genome shotgun sequence - Tetraodon
nigroviridis (Green puffer)
Length = 351
Score = 35.1 bits (77), Expect = 0.31
Identities = 19/47 (40%), Positives = 25/47 (53%)
Frame = +2
Query: 104 MAPSCALYVALACILAVVASDLPHPLSDAFXNLINKKQNTWKAGRNF 244
M P+ L++A A ++ L PLS N INK +TW AG NF
Sbjct: 1 MWPAAFLFLAAAWSSSLARPHLK-PLSSEMVNYINKLNSTWTAGHNF 46
>UniRef50_A7LM75 Cluster: Cathepsin B preproprotein precursor; n=1;
Biomphalaria glabrata|Rep: Cathepsin B preproprotein
precursor - Biomphalaria glabrata (Bloodfluke planorb)
Length = 333
Score = 34.3 bits (75), Expect = 0.55
Identities = 22/44 (50%), Positives = 26/44 (59%), Gaps = 3/44 (6%)
Frame = +2
Query: 122 LYVALACILAVVASDLPH--PLSDAFXNLINKKQNT-WKAGRNF 244
+ VA+ +LAV + H PLSDA IN NT WKAGRNF
Sbjct: 6 ILVAICGLLAVALATPFHIEPLSDAEIFYINHVANTTWKAGRNF 49
>UniRef50_Q5VJM8 Cluster: Cathepsin B-like cysteine protease; n=2;
Arthropoda|Rep: Cathepsin B-like cysteine protease -
Callosobruchus maculatus (Southern cowpea weevil) (Pulse
bruchid)
Length = 330
Score = 33.9 bits (74), Expect = 0.72
Identities = 19/52 (36%), Positives = 25/52 (48%), Gaps = 4/52 (7%)
Frame = +2
Query: 128 VALACILAVVASDLPHP----LSDAFXNLINKKQNTWKAGRNFPTHTPFAHI 271
+A + AVV+ P LSD + +N K WKAGRNF T +I
Sbjct: 3 LAFIALAAVVSCTFAQPELDFLSDEYIEQLNSKNLPWKAGRNFERDTSLYNI 54
>UniRef50_Q8MNY7 Cluster: Cathepsin B-like protease precursor; n=1;
Nilaparvata lugens|Rep: Cathepsin B-like protease
precursor - Nilaparvata lugens (Brown planthopper)
Length = 347
Score = 31.9 bits (69), Expect = 2.9
Identities = 16/59 (27%), Positives = 32/59 (54%), Gaps = 2/59 (3%)
Frame = +2
Query: 116 CALYVALACILAVVASD-LPHPLSDAFXNLINKK-QNTWKAGRNFPTHTPFAHITIXMG 286
C L+ ++ I A+ + +++ + + IN ++TWKAG NF TP +++ +G
Sbjct: 6 CLLFAVVSAISALPDQENTVREIANKWIDAINNNPKSTWKAGHNFHPDTPMSYLQGLLG 64
>UniRef50_Q6FU29 Cluster: Candida glabrata strain CBS138 chromosome
F complete sequence; n=1; Candida glabrata|Rep: Candida
glabrata strain CBS138 chromosome F complete sequence -
Candida glabrata (Yeast) (Torulopsis glabrata)
Length = 1092
Score = 30.7 bits (66), Expect = 6.7
Identities = 17/55 (30%), Positives = 29/55 (52%)
Frame = +2
Query: 65 NRSTL*KKIKY*KMAPSCALYVALACILAVVASDLPHPLSDAFXNLINKKQNTWK 229
N +T KK+ Y ++AP YV A + + + LPH LS + +++ +N K
Sbjct: 113 NTNTTAKKVNYGRLAPIDTQYVNPADFVDIRSDSLPHMLSVSGLPQVSRVENQLK 167
>UniRef50_Q4T0Z0 Cluster: Chromosome 12 SCAF10787, whole genome
shotgun sequence; n=2; Tetraodontidae|Rep: Chromosome 12
SCAF10787, whole genome shotgun sequence - Tetraodon
nigroviridis (Green puffer)
Length = 273
Score = 30.3 bits (65), Expect = 8.9
Identities = 13/43 (30%), Positives = 23/43 (53%)
Frame = -1
Query: 286 SHXYCDVCKRCMRREVPASFPCVLFLINQIXKRI*ERMGQVTG 158
+H +C+ C R + R PA+ PC L + + + G++TG
Sbjct: 80 NHIFCEPCLRTLARNSPANTPCP--LCRTVITHVFFQKGELTG 120
>UniRef50_Q8T659 Cluster: Cathepsin B; n=1; Apriona germari|Rep:
Cathepsin B - Apriona germari
Length = 324
Score = 30.3 bits (65), Expect = 8.9
Identities = 12/26 (46%), Positives = 16/26 (61%)
Frame = +2
Query: 182 SDAFXNLINKKQNTWKAGRNFPTHTP 259
++AF IN+K TW A +NF TP
Sbjct: 28 TEAFIQSINEKATTWTARKNFEGRTP 53
>UniRef50_Q7QWK3 Cluster: GLP_762_51859_50456; n=1; Giardia lamblia
ATCC 50803|Rep: GLP_762_51859_50456 - Giardia lamblia
ATCC 50803
Length = 467
Score = 30.3 bits (65), Expect = 8.9
Identities = 8/24 (33%), Positives = 16/24 (66%)
Frame = -1
Query: 292 QGSHXYCDVCKRCMRREVPASFPC 221
QG H +CD+C++C +++ + C
Sbjct: 182 QGEHKHCDICRQCYKKQFFDTHKC 205
>UniRef50_Q6L8N8 Cluster: Cathepsin B-S precursor; n=15;
Aphidoidea|Rep: Cathepsin B-S precursor - Tuberaphis
styraci
Length = 349
Score = 30.3 bits (65), Expect = 8.9
Identities = 18/49 (36%), Positives = 24/49 (48%), Gaps = 3/49 (6%)
Frame = +2
Query: 119 ALYVALACILAV---VASDLPHPLSDAFXNLINKKQNTWKAGRNFPTHT 256
A +V + C + V +A LSD IN+ TWKA R FP +T
Sbjct: 2 AKFVTIVCAIFVSVYLAEPTLQFLSDERIKYINEVAKTWKAERYFPANT 50
>UniRef50_Q8NIS9 Cluster: Putative uncharacterized protein
B23E9.050; n=1; Neurospora crassa|Rep: Putative
uncharacterized protein B23E9.050 - Neurospora crassa
Length = 954
Score = 30.3 bits (65), Expect = 8.9
Identities = 21/68 (30%), Positives = 36/68 (52%)
Frame = -1
Query: 241 VPASFPCVLFLINQIXKRI*ERMGQVTGHNSENTRERDVQSTRRSHLSVFYFLLQSRSVN 62
+PA F C++ L+N + ++ ER G S+ R+ D+ R + ++ F LL + V
Sbjct: 583 LPALFRCLIRLLNILAEKPDERQGDFI---SDLCRQFDIGKPRFTQIT-FALLLTASVVY 638
Query: 61 KLTRNSNE 38
L R SN+
Sbjct: 639 ALERQSND 646
>UniRef50_Q7RXE3 Cluster: Predicted protein; n=1; Neurospora
crassa|Rep: Predicted protein - Neurospora crassa
Length = 831
Score = 30.3 bits (65), Expect = 8.9
Identities = 21/68 (30%), Positives = 36/68 (52%)
Frame = -1
Query: 241 VPASFPCVLFLINQIXKRI*ERMGQVTGHNSENTRERDVQSTRRSHLSVFYFLLQSRSVN 62
+PA F C++ L+N + ++ ER G S+ R+ D+ R + ++ F LL + V
Sbjct: 498 LPALFRCLIRLLNILAEKPDERQGDFI---SDLCRQFDIGKPRFTQIT-FALLLTASVVY 553
Query: 61 KLTRNSNE 38
L R SN+
Sbjct: 554 ALERQSND 561
>UniRef50_Q4WAY3 Cluster: Polyketide synthase, putative; n=1;
Aspergillus fumigatus|Rep: Polyketide synthase, putative
- Aspergillus fumigatus (Sartorya fumigata)
Length = 2462
Score = 30.3 bits (65), Expect = 8.9
Identities = 14/30 (46%), Positives = 16/30 (53%)
Frame = -3
Query: 185 LRADGASHWPQQREYTRARRTEHTKEPSFS 96
L AD S W +E T AR +EH P FS
Sbjct: 635 LPADLKSEWSLLQELTEARSSEHLSRPEFS 664
Database: uniref50
Posted date: Oct 5, 2007 11:19 AM
Number of letters in database: 575,637,011
Number of sequences in database: 1,657,284
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 276,544,465
Number of Sequences: 1657284
Number of extensions: 4635019
Number of successful extensions: 12990
Number of sequences better than 10.0: 19
Number of HSP's better than 10.0 without gapping: 12751
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 12988
length of database: 575,637,011
effective HSP length: 75
effective length of database: 451,340,711
effective search space used: 10380836353
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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