Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= I10A02NGRL0005_K13
(596 letters)
Database: uniref50
1,657,284 sequences; 575,637,011 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
UniRef50_P26267 Cluster: Pyruvate dehydrogenase E1 component sub... 172 6e-42
UniRef50_Q6NX32 Cluster: Pyruvate dehydrogenase (Lipoamide) alph... 160 2e-38
UniRef50_P08559 Cluster: Pyruvate dehydrogenase E1 component sub... 157 1e-37
UniRef50_Q9W4H4 Cluster: CG7024-PA; n=2; Sophophora|Rep: CG7024-... 141 1e-32
UniRef50_P16387 Cluster: Pyruvate dehydrogenase E1 component sub... 127 2e-28
UniRef50_Q1EGI2 Cluster: Pyruvate dehydrogenase E1 alpha subunit... 123 3e-27
UniRef50_Q4QDQ1 Cluster: Pyruvate dehydrogenase E1 component alp... 120 3e-26
UniRef50_Q8H1Y0 Cluster: Pyruvate dehydrogenase E1 component sub... 117 2e-25
UniRef50_A2QWB4 Cluster: Catalytic activity: Pyruvate + Lipoamid... 116 4e-25
UniRef50_O96865 Cluster: Pyruvate dehydrogenase E1 alpha subunit... 115 1e-24
UniRef50_Q9R9N5 Cluster: Pyruvate dehydrogenase E1 component sub... 111 9e-24
UniRef50_Q5FNM5 Cluster: Pyruvate dehydrogenase E1 component alp... 108 8e-23
UniRef50_Q23KL2 Cluster: Pyruvate dehydrogenase E1 component; n=... 102 6e-21
UniRef50_Q4T3C0 Cluster: Chromosome undetermined SCAF10102, whol... 93 6e-18
UniRef50_Q4WHM5 Cluster: Pyruvate dehydrogenase E1 component alp... 93 6e-18
UniRef50_A7CXZ4 Cluster: Pyruvate dehydrogenase; n=1; Opitutacea... 91 2e-17
UniRef50_O66112 Cluster: Pyruvate dehydrogenase E1 component sub... 90 3e-17
UniRef50_Q8TA29 Cluster: Putative pyruvate dehydrogenase; n=1; H... 87 2e-16
UniRef50_A6Q3I6 Cluster: Pyruvate/2-oxoglutarate dehydrogenase c... 87 4e-16
UniRef50_Q1XDM0 Cluster: Pyruvate dehydrogenase E1 component sub... 87 4e-16
UniRef50_A4VXG8 Cluster: Pyruvate/2-oxoglutarate dehydrogenase c... 85 9e-16
UniRef50_A3VIE7 Cluster: Tpp-dependent acetoin dehydrogenase e1 ... 85 9e-16
UniRef50_Q1AZ54 Cluster: Pyruvate dehydrogenase; n=1; Rubrobacte... 85 2e-15
UniRef50_Q42066 Cluster: Pyruvate dehydrogenase E1 componen; n=5... 83 4e-15
UniRef50_A5UVY9 Cluster: Pyruvate dehydrogenase; n=2; Roseiflexu... 82 1e-14
UniRef50_A5UU15 Cluster: Pyruvate dehydrogenase; n=3; Chloroflex... 80 3e-14
UniRef50_Q74AD3 Cluster: Dehydrogenase complex, E1 component, al... 79 1e-13
UniRef50_Q3J9C5 Cluster: Dehydrogenase, E1 component; n=3; Prote... 78 1e-13
UniRef50_Q1KSF1 Cluster: Apicoplast pyruvate dehydrogenase E1 al... 78 2e-13
UniRef50_Q1NYU1 Cluster: Pyruvate dehydrogenase E1 component alp... 77 2e-13
UniRef50_Q18CB6 Cluster: Acetoin:2,6-dichlorophenolindophenol ox... 77 2e-13
UniRef50_A0LTQ9 Cluster: Pyruvate dehydrogenase; n=1; Acidotherm... 75 2e-12
UniRef50_A6DTS3 Cluster: Dehydrogenase complex, E1 component, al... 74 3e-12
UniRef50_Q8ZUR8 Cluster: Pyruvate dehydrogenase E1 alpha subunit... 74 3e-12
UniRef50_Q9LPL5 Cluster: Branched-chain alpha keto-acid dehydrog... 73 5e-12
UniRef50_Q0W151 Cluster: Pyruvate dehydrogenase complex E1, tran... 73 5e-12
UniRef50_A7HBV0 Cluster: 3-methyl-2-oxobutanoate dehydrogenase; ... 73 7e-12
UniRef50_Q4QC52 Cluster: 2-oxoisovalerate dehydrogenase alpha su... 73 7e-12
UniRef50_Q1IQR3 Cluster: Dehydrogenase, E1 component; n=1; Acido... 72 9e-12
UniRef50_A0LSF3 Cluster: Pyruvate dehydrogenase; n=5; Bacteria|R... 72 1e-11
UniRef50_Q98FT3 Cluster: Acetoin dehydrogenase (TPP-dependent) a... 71 2e-11
UniRef50_Q12FH4 Cluster: Pyruvate dehydrogenase; n=37; Bacteria|... 71 3e-11
UniRef50_Q5QUK4 Cluster: Alpha keto acid dehydrogenase complex, ... 70 4e-11
UniRef50_Q4DB65 Cluster: 2-oxoisovalerate dehydrogenase alpha su... 70 5e-11
UniRef50_Q72GU1 Cluster: 2-oxoisovalerate dehydrogenase subunit ... 70 5e-11
UniRef50_Q2S150 Cluster: Pyruvate dehydrogenase E1 component, al... 69 6e-11
UniRef50_P47516 Cluster: Pyruvate dehydrogenase E1 component sub... 69 6e-11
UniRef50_A4AFX0 Cluster: Acetoin dehydrogenase (TPP-dependent) a... 69 8e-11
UniRef50_Q8AB00 Cluster: 2-oxoisovalerate dehydrogenase beta sub... 69 1e-10
UniRef50_Q1ATM5 Cluster: Pyruvate dehydrogenase; n=1; Rubrobacte... 68 2e-10
UniRef50_Q1ARM0 Cluster: Pyruvate dehydrogenase; n=3; Bacteria|R... 67 3e-10
UniRef50_Q0RVK8 Cluster: Probable pyruvate dehydrogenase; n=1; R... 67 3e-10
UniRef50_A0LLM4 Cluster: Pyruvate dehydrogenase; n=1; Syntrophob... 67 3e-10
UniRef50_Q3E8Q6 Cluster: Uncharacterized protein At5g34780.1; n=... 66 4e-10
UniRef50_Q4MTG0 Cluster: Pyruvate dehydrogenase E1 component sub... 66 4e-10
UniRef50_Q9KG99 Cluster: Pyruvate dehydrogenase E1 (Lipoamide) a... 66 8e-10
UniRef50_Q67ME6 Cluster: Branched-chain alpha-keto acid dehydrog... 64 2e-09
UniRef50_Q02C52 Cluster: Pyruvate dehydrogenase; n=1; Solibacter... 64 2e-09
UniRef50_Q3DZ88 Cluster: Dehydrogenase, E1 component; n=1; Chlor... 64 3e-09
UniRef50_Q97YF6 Cluster: Pyruvate dehydrogenase, alpha subunit (... 64 3e-09
UniRef50_P37940 Cluster: 2-oxoisovalerate dehydrogenase subunit ... 64 3e-09
UniRef50_Q835M4 Cluster: Pyruvate dehydrogenase complex E1 compo... 63 4e-09
UniRef50_Q9RPS5 Cluster: TPP-dependent branched-chain alpha-keto... 63 4e-09
UniRef50_P27745 Cluster: Acetoin:2,6-dichlorophenolindophenol ox... 63 4e-09
UniRef50_A5V4J0 Cluster: Pyruvate dehydrogenase; n=2; Sphingomon... 63 6e-09
UniRef50_Q020J5 Cluster: Dehydrogenase, E1 component; n=1; Solib... 61 2e-08
UniRef50_Q6MAE2 Cluster: Putative pyruvate dehydrogenase (Lipoam... 61 2e-08
UniRef50_Q8CX87 Cluster: Pyruvate dehydrogenase E1 (Lipoamide) a... 60 3e-08
UniRef50_Q67SE7 Cluster: Pyruvate dehydrogenase E1 alpha subunit... 60 3e-08
UniRef50_Q6YPX5 Cluster: Thiamine pyrophosphate-dependent dehydr... 60 4e-08
UniRef50_Q97CK0 Cluster: 2-oxoisovalerate dehydrogenase alpha su... 60 4e-08
UniRef50_P35485 Cluster: Pyruvate dehydrogenase E1 component sub... 60 4e-08
UniRef50_Q2J998 Cluster: Pyruvate dehydrogenase; n=1; Frankia sp... 60 5e-08
UniRef50_A4XHV5 Cluster: Transketolase, central region; n=3; Bac... 60 5e-08
UniRef50_Q49108 Cluster: Pyruvate dehydrogenase EI alpha subunit... 59 9e-08
UniRef50_A7K3C9 Cluster: Dehydrogenase E1 component superfamily;... 59 9e-08
UniRef50_Q749T8 Cluster: Pyruvate dehydrogenase complex E1 compo... 58 1e-07
UniRef50_Q3WCG3 Cluster: Pyruvate dehydrogenase; n=4; Actinomyce... 58 1e-07
UniRef50_Q4A1S8 Cluster: Putative uncharacterized protein; n=4; ... 58 1e-07
UniRef50_P21873 Cluster: Pyruvate dehydrogenase E1 component sub... 58 1e-07
UniRef50_A6W004 Cluster: Transketolase domain protein; n=6; Prot... 58 2e-07
UniRef50_Q9RYC1 Cluster: 2-oxo acid dehydrogenase, E1 component,... 58 2e-07
UniRef50_A3CMZ3 Cluster: Pyruvate dehydrogenase, TPP-dependent E... 58 2e-07
UniRef50_Q5KUY4 Cluster: Pyruvate dehydrogenase E1 (Lipoamide) a... 57 3e-07
UniRef50_Q3DYK5 Cluster: Dehydrogenase, E1 component; n=3; Bacte... 57 3e-07
UniRef50_P12694 Cluster: 2-oxoisovalerate dehydrogenase subunit ... 57 3e-07
UniRef50_A6CP23 Cluster: Pyruvate dehydrogenase E1 (Lipoamide) a... 57 4e-07
UniRef50_A6GG24 Cluster: Pyruvate dehydrogenase (Lipoamide), alp... 56 5e-07
UniRef50_Q6A611 Cluster: Pyruvate dehydrogenase E1 component, al... 56 6e-07
UniRef50_Q2JA37 Cluster: Pyruvate dehydrogenase; n=11; Actinomyc... 56 6e-07
UniRef50_Q53610 Cluster: Branched-chain alpha-keto acid dehydrog... 56 8e-07
UniRef50_A3RZM3 Cluster: Pyruvate dehydrogenase E1 component alp... 55 1e-06
UniRef50_A0UXT3 Cluster: Pyruvate dehydrogenase; n=1; Clostridiu... 55 1e-06
UniRef50_Q3W421 Cluster: Pyruvate dehydrogenase; n=1; Frankia sp... 55 1e-06
UniRef50_Q1IY28 Cluster: Pyruvate dehydrogenase; n=1; Deinococcu... 55 1e-06
UniRef50_Q9VHB8 Cluster: CG8199-PA; n=2; Eukaryota|Rep: CG8199-P... 54 3e-06
UniRef50_A3SJ75 Cluster: 2-oxoisovalerate dehydrogenase beta sub... 53 4e-06
UniRef50_Q9Z8N4 Cluster: Pyruvate Dehydrogenase Alpha; n=8; Chla... 53 6e-06
UniRef50_Q5SJR9 Cluster: Pyruvate dehydrogenase (Lipoamide) (EC ... 53 6e-06
UniRef50_A7BPK6 Cluster: Pyruvate dehydrogenase; n=1; Beggiatoa ... 53 6e-06
UniRef50_A0K283 Cluster: Pyruvate dehydrogenase; n=4; Actinobact... 53 6e-06
UniRef50_Q4P2J0 Cluster: Putative uncharacterized protein; n=1; ... 53 6e-06
UniRef50_A6WG12 Cluster: Pyruvate dehydrogenase; n=3; Actinomyce... 52 8e-06
UniRef50_A4XF89 Cluster: Dehydrogenase, E1 component; n=1; Novos... 52 8e-06
UniRef50_Q8D6Q7 Cluster: Pyruvate/2-oxoglutarate dehydrogenase c... 52 1e-05
UniRef50_Q4L1A7 Cluster: Pyruvate dehydrogenase E1 component alp... 52 1e-05
UniRef50_A5IXN2 Cluster: Pyruvate dehydrogenase E1 component, al... 52 1e-05
UniRef50_A1UJ85 Cluster: Pyruvate dehydrogenase; n=16; Mycobacte... 52 1e-05
UniRef50_A0LFE6 Cluster: Pyruvate dehydrogenase; n=1; Syntrophob... 52 1e-05
UniRef50_A0JUQ5 Cluster: Pyruvate dehydrogenase; n=4; Actinobact... 52 1e-05
UniRef50_Q295J7 Cluster: GA20891-PA; n=7; Coelomata|Rep: GA20891... 52 1e-05
UniRef50_A7RZV6 Cluster: Predicted protein; n=6; Eumetazoa|Rep: ... 52 1e-05
UniRef50_Q8YDW3 Cluster: 2-OXOISOVALERATE DEHYDROGENASE BETA SUB... 51 2e-05
UniRef50_A6UDY5 Cluster: Dehydrogenase E1 component; n=2; Alphap... 51 2e-05
UniRef50_A0JY23 Cluster: Pyruvate dehydrogenase; n=2; Arthrobact... 51 2e-05
UniRef50_Q83FF2 Cluster: Pyruvate dehydrogenase E1 component alp... 51 2e-05
UniRef50_Q2ITF8 Cluster: Acetoin dehydrogenase (TPP-dependent) a... 51 2e-05
UniRef50_A0DAM1 Cluster: Chromosome undetermined scaffold_43, wh... 51 2e-05
UniRef50_Q9YBC0 Cluster: Pyruvate dehydrogenase E1 component, al... 51 2e-05
UniRef50_Q5KGR5 Cluster: Branched-chain alpha-keto acid dehydrog... 50 3e-05
UniRef50_UPI00005103B4 Cluster: COG1071: Pyruvate/2-oxoglutarate... 50 4e-05
UniRef50_Q11G20 Cluster: Twin-arginine translocation pathway sig... 50 4e-05
UniRef50_Q13GQ3 Cluster: Putative 2-oxo acid dehydrogenase alpha... 50 5e-05
UniRef50_Q8EVQ2 Cluster: Pyruvate dehydrogenase E1 component sub... 49 7e-05
UniRef50_Q479Q2 Cluster: Dehydrogenase, E1 component; n=2; Rhodo... 48 1e-04
UniRef50_Q9HNV6 Cluster: Pyruvate dehydrogenase alpha subunit; n... 48 1e-04
UniRef50_A5V557 Cluster: Pyruvate dehydrogenase; n=1; Sphingomon... 48 2e-04
UniRef50_Q00TN9 Cluster: Pyruvate dehydrogenase E1 component bet... 48 2e-04
UniRef50_Q4N1L6 Cluster: Branched-chain alpha keto-acid dehydrog... 48 2e-04
UniRef50_Q8U4T5 Cluster: 2-oxo acid dehydrogenase subunit E1; n=... 48 2e-04
UniRef50_Q8YDG0 Cluster: 2-OXOISOVALERATE DEHYDROGENASE BETA SUB... 47 3e-04
UniRef50_Q4Y3F8 Cluster: Branched-chain alpha keto-acid dehydrog... 47 3e-04
UniRef50_P09060 Cluster: 2-oxoisovalerate dehydrogenase subunit ... 47 3e-04
UniRef50_Q0MX87 Cluster: Acetoin dehydrogenase alpha-subunit; n=... 47 4e-04
UniRef50_A4X7T3 Cluster: Dehydrogenase, E1 component; n=3; Actin... 47 4e-04
UniRef50_Q83X26 Cluster: Probable pyruvate dehydrogenase alpha-s... 46 5e-04
UniRef50_Q1LFS5 Cluster: Dehydrogenase, E1 component; n=22; Prot... 46 5e-04
UniRef50_A3PXW7 Cluster: Transketolase domain protein; n=4; Myco... 46 5e-04
UniRef50_A4F1Y5 Cluster: Branched-chain alpha-keto acid decarbox... 46 9e-04
UniRef50_Q9Z9E8 Cluster: (Pyruvate) Oxoisovalerate Dehydrogenase... 45 0.001
UniRef50_Q83DQ6 Cluster: Dehydrogenase, E1 component, alpha subu... 45 0.001
UniRef50_Q8SQM8 Cluster: PYRUVATE DEHYDROGENASE E1 COMPONENT ALP... 45 0.001
UniRef50_Q8PQ82 Cluster: Pyruvate dehydrogenase E1 alpha subunit... 44 0.002
UniRef50_Q5LVW0 Cluster: Dehydrogenase/transketolase family prot... 44 0.002
UniRef50_A0M1U4 Cluster: 2-oxoisovalerate dehydrogenase E1 compo... 44 0.003
UniRef50_Q1KSF2 Cluster: Mitochondrial branched-chain alpha-keto... 44 0.003
UniRef50_Q0RLC2 Cluster: Pyruvate dehydrogenase E1 component, al... 44 0.004
UniRef50_Q5VGY4 Cluster: Pyruvate dehydrogenase alpha subunit; n... 43 0.006
UniRef50_Q023C4 Cluster: Pyruvate dehydrogenase; n=1; Solibacter... 42 0.008
UniRef50_Q319T4 Cluster: Pyruvate dehydrogenase; n=1; Prochloroc... 42 0.011
UniRef50_A3TUC4 Cluster: TPP-dependent acetoin dehydrogenase com... 42 0.011
UniRef50_A0HHH5 Cluster: Dehydrogenase, E1 component; n=2; Bacte... 42 0.015
UniRef50_Q9HN77 Cluster: Pyruvate dehydrogenase alpha subunit; n... 41 0.019
UniRef50_A5V540 Cluster: Dehydrogenase, E1 component; n=3; Prote... 41 0.025
UniRef50_Q28MR4 Cluster: Dehydrogenase E1 component; n=8; Bacter... 40 0.034
UniRef50_A1SN84 Cluster: Pyruvate dehydrogenase; n=12; Bacteria|... 40 0.034
UniRef50_Q95VS6 Cluster: Pyruvate dehydrogenase E1 alpha subunit... 40 0.044
UniRef50_Q0LRY7 Cluster: Dehydrogenase, E1 component:Transketola... 40 0.059
UniRef50_Q93N50 Cluster: Pyruvate dehydrogenase alpha subunit; n... 39 0.078
UniRef50_Q4SEP7 Cluster: Chromosome 3 SCAF14614, whole genome sh... 39 0.10
UniRef50_Q6L1L8 Cluster: Pyruvate dehydrogenase E1 component alp... 37 0.31
UniRef50_A0BCX8 Cluster: Chromosome undetermined scaffold_10, wh... 37 0.41
UniRef50_A7D3P2 Cluster: Pyruvate dehydrogenase; n=1; Halorubrum... 37 0.41
UniRef50_UPI0000E80F2F Cluster: PREDICTED: hypothetical protein;... 36 0.55
UniRef50_Q4RFZ6 Cluster: Chromosome undetermined SCAF15108, whol... 36 0.55
UniRef50_Q4T4Q5 Cluster: Chromosome undetermined SCAF9565, whole... 36 0.72
UniRef50_Q7VR91 Cluster: 2-oxoglutarate dehydrogenase E1 compone... 36 0.72
UniRef50_UPI0000EBDC73 Cluster: PREDICTED: hypothetical protein ... 35 1.3
UniRef50_A5NZK1 Cluster: Methyl-accepting chemotaxis sensory tra... 35 1.3
UniRef50_Q6YXU3 Cluster: Putative uncharacterized protein P0427G... 35 1.3
UniRef50_A7EFP6 Cluster: Predicted protein; n=1; Sclerotinia scl... 35 1.3
UniRef50_UPI00015C4945 Cluster: hypothetical protein CCC13826_09... 35 1.7
UniRef50_A5U0N1 Cluster: Dehydrogenase E1 component; n=7; Mycoba... 35 1.7
UniRef50_Q4N6Q9 Cluster: Putative uncharacterized protein; n=2; ... 35 1.7
UniRef50_Q16GX6 Cluster: Pickpocket; n=1; Aedes aegypti|Rep: Pic... 35 1.7
UniRef50_Q04632 Cluster: Conserved oligomeric Golgi complex subu... 35 1.7
UniRef50_UPI0000D9E76F Cluster: PREDICTED: hypothetical protein;... 34 2.2
UniRef50_Q748I3 Cluster: Dehydrogenase, E1 component, alpha and ... 34 2.2
UniRef50_Q0DJL7 Cluster: Os05g0263200 protein; n=13; Eukaryota|R... 34 2.2
UniRef50_A7PGG3 Cluster: Chromosome chr17 scaffold_16, whole gen... 34 2.2
UniRef50_A7D571 Cluster: Putative uncharacterized protein precur... 34 2.9
UniRef50_Q88X31 Cluster: Putative uncharacterized protein lp_141... 33 3.9
UniRef50_A4CGF1 Cluster: 2-oxoglutarate dehydrogenase, E1 compon... 33 3.9
UniRef50_A0GJ77 Cluster: Putative uncharacterized protein; n=4; ... 33 3.9
UniRef50_Q0UT66 Cluster: Predicted protein; n=1; Phaeosphaeria n... 33 3.9
UniRef50_UPI0000DD83A2 Cluster: PREDICTED: hypothetical protein;... 33 5.1
UniRef50_Q7N3C2 Cluster: Similar to 3-methyl-2-oxobutanoate dehy... 33 5.1
UniRef50_A0QB51 Cluster: Dehydrogenase E1 component superfamily ... 33 5.1
UniRef50_Q7QI36 Cluster: ENSANGP00000020537; n=1; Anopheles gamb... 33 5.1
UniRef50_Q6CLM5 Cluster: DNA polymerase epsilon subunit C; n=1; ... 33 5.1
UniRef50_UPI00015B4C52 Cluster: PREDICTED: similar to conserved ... 33 6.7
UniRef50_UPI0000D56C7C Cluster: PREDICTED: similar to CG14039-PE... 33 6.7
UniRef50_UPI000049936A Cluster: Activator 1 140 kDa subunit; n=1... 33 6.7
UniRef50_Q6ZXZ8 Cluster: Nitrous oxide reductase precursor; n=13... 33 6.7
UniRef50_A1GCL6 Cluster: Transketolase-like; n=2; Salinispora|Re... 33 6.7
UniRef50_Q6Z707 Cluster: Non-ribosomal peptide synthetase module... 33 6.7
UniRef50_A7SY99 Cluster: Predicted protein; n=1; Nematostella ve... 33 6.7
UniRef50_A7ATF7 Cluster: Putative uncharacterized protein; n=1; ... 33 6.7
UniRef50_Q4UKI8 Cluster: 2-oxoglutarate dehydrogenase E1 compone... 33 6.7
UniRef50_UPI000150A2A6 Cluster: Kelch motif family protein; n=1;... 32 8.9
UniRef50_UPI0000499807 Cluster: UV excision repair protein RAD23... 32 8.9
UniRef50_UPI000023E47E Cluster: hypothetical protein FG05604.1; ... 32 8.9
UniRef50_Q2S3D2 Cluster: 2-oxoglutarate dehydrogenase, E1 compon... 32 8.9
UniRef50_Q02AM5 Cluster: CRISPR-associated protein, Csm2 family;... 32 8.9
UniRef50_A5P1Z2 Cluster: Riboflavin biosynthesis protein RibD; n... 32 8.9
UniRef50_A5P159 Cluster: Major facilitator superfamily MFS_1 pre... 32 8.9
UniRef50_A4YXU9 Cluster: Flagellar basal-body rod protein FlgC; ... 32 8.9
UniRef50_Q9BLX9 Cluster: Intermediate filament protein IF-B; n=1... 32 8.9
UniRef50_A0BYZ2 Cluster: Chromosome undetermined scaffold_138, w... 32 8.9
UniRef50_A6SRK7 Cluster: Predicted protein; n=1; Botryotinia fuc... 32 8.9
UniRef50_Q10030 Cluster: Uncharacterized protein C27D6.1; n=2; C... 32 8.9
UniRef50_Q02388 Cluster: Collagen alpha-1(VII) chain precursor; ... 32 8.9
>UniRef50_P26267 Cluster: Pyruvate dehydrogenase E1 component
subunit alpha type I, mitochondrial precursor; n=10;
cellular organisms|Rep: Pyruvate dehydrogenase E1
component subunit alpha type I, mitochondrial precursor
- Ascaris suum (Pig roundworm) (Ascaris lumbricoides)
Length = 396
Score = 172 bits (418), Expect = 6e-42
Identities = 78/125 (62%), Positives = 99/125 (79%)
Frame = +2
Query: 2 GMDVIATREATKFAIDYCTSGKGPLLIEMETYRYSGHSMSDPGTSYRTRDEVQEVRQTRD 181
GMDV+A R+A ++A ++C +GKGPL+IEM TYRYSGHSMSDPGTSYRTR+EVQEVR+TRD
Sbjct: 252 GMDVLAVRQAVRWAKEWCNAGKGPLMIEMATYRYSGHSMSDPGTSYRTREEVQEVRKTRD 311
Query: 182 PITSFKEKVINNQLVTPDQLKEIDAKVRKETDEASKQAKADPEIPIEELSGDIYYSNLEP 361
PIT FK+K++ LVT D++KEID +VRKE D A KQA D E P+E + DIYY+
Sbjct: 312 PITGFKDKIVTAGLVTEDEIKEIDKQVRKEIDAAVKQAHTDKESPVELMLTDIYYNTPAQ 371
Query: 362 FIRGT 376
++R T
Sbjct: 372 YVRCT 376
>UniRef50_Q6NX32 Cluster: Pyruvate dehydrogenase (Lipoamide) alpha
1; n=3; Tetrapoda|Rep: Pyruvate dehydrogenase
(Lipoamide) alpha 1 - Xenopus tropicalis (Western clawed
frog) (Silurana tropicalis)
Length = 369
Score = 160 bits (389), Expect = 2e-38
Identities = 71/126 (56%), Positives = 97/126 (76%)
Frame = +2
Query: 2 GMDVIATREATKFAIDYCTSGKGPLLIEMETYRYSGHSMSDPGTSYRTRDEVQEVRQTRD 181
GMDV+ REAT+FA D+C SGKGP+L+E++TYRY GHSMSDPG SYRTR+E+QEVR D
Sbjct: 235 GMDVLCVREATQFAADHCRSGKGPILMELQTYRYHGHSMSDPGVSYRTREEIQEVRSKSD 294
Query: 182 PITSFKEKVINNQLVTPDQLKEIDAKVRKETDEASKQAKADPEIPIEELSGDIYYSNLEP 361
PIT K++++NN L + ++LKEID +VRKE +EA++ A DPE P+EE++ IY +
Sbjct: 295 PITLLKDRMLNNNLSSVEELKEIDVEVRKEIEEAAQFATTDPEPPLEEIANHIYNNEPTF 354
Query: 362 FIRGTH 379
+RG +
Sbjct: 355 DVRGAN 360
>UniRef50_P08559 Cluster: Pyruvate dehydrogenase E1 component
subunit alpha, somatic form, mitochondrial precursor;
n=110; cellular organisms|Rep: Pyruvate dehydrogenase E1
component subunit alpha, somatic form, mitochondrial
precursor - Homo sapiens (Human)
Length = 390
Score = 157 bits (382), Expect = 1e-37
Identities = 72/127 (56%), Positives = 98/127 (77%), Gaps = 1/127 (0%)
Frame = +2
Query: 2 GMDVIATREATKFAIDYCTSGKGPLLIEMETYRYSGHSMSDPGTSYRTRDEVQEVRQTRD 181
GMD++ REAT+FA YC SGKGP+L+E++TYRY GHSMSDPG SYRTR+E+QEVR D
Sbjct: 256 GMDILCVREATRFAAAYCRSGKGPILMELQTYRYHGHSMSDPGVSYRTREEIQEVRSKSD 315
Query: 182 PITSFKEKVINNQLVTPDQLKEIDAKVRKETDEASKQAKADPEIPIEELSGDIYYSNLEP 361
PI K++++N+ L + ++LKEID +VRKE ++A++ A ADPE P+EEL IY S+ P
Sbjct: 316 PIMLLKDRMVNSNLASVEELKEIDVEVRKEIEDAAQFATADPEPPLEELGYHIYSSD-PP 374
Query: 362 F-IRGTH 379
F +RG +
Sbjct: 375 FEVRGAN 381
>UniRef50_Q9W4H4 Cluster: CG7024-PA; n=2; Sophophora|Rep: CG7024-PA
- Drosophila melanogaster (Fruit fly)
Length = 479
Score = 141 bits (342), Expect = 1e-32
Identities = 68/137 (49%), Positives = 94/137 (68%)
Frame = +2
Query: 2 GMDVIATREATKFAIDYCTSGKGPLLIEMETYRYSGHSMSDPGTSYRTRDEVQEVRQTRD 181
G V+A R AT+FA+D+ GP+++EM TYRY GHSMSDPGTSYR+R+EVQ R+ RD
Sbjct: 258 GNQVLAVRSATQFAVDHALK-HGPIVLEMSTYRYVGHSMSDPGTSYRSREEVQSTREKRD 316
Query: 182 PITSFKEKVINNQLVTPDQLKEIDAKVRKETDEASKQAKADPEIPIEELSGDIYYSNLEP 361
PITSF+ ++I L ++LK +D K RK+ D K+A D E+ ++EL DIY N++
Sbjct: 317 PITSFRSQIIALCLADEEELKALDDKTRKQVDSICKKATTDREVELDELHTDIYAKNVDG 376
Query: 362 FIRGTHPGAQLQHIQVA 412
IRG G L+HI++A
Sbjct: 377 KIRGV-SGFHLEHIKLA 392
>UniRef50_P16387 Cluster: Pyruvate dehydrogenase E1 component
subunit alpha, mitochondrial precursor; n=34;
Dikarya|Rep: Pyruvate dehydrogenase E1 component subunit
alpha, mitochondrial precursor - Saccharomyces
cerevisiae (Baker's yeast)
Length = 420
Score = 127 bits (306), Expect = 2e-28
Identities = 63/130 (48%), Positives = 82/130 (63%), Gaps = 3/130 (2%)
Frame = +2
Query: 2 GMDVIATREATKFAIDYCTSGKGPLLIEMETYRYSGHSMSDPGTSYRTRDEVQEVRQTRD 181
GMD++A +A+KFA D+C SGKGPL++E ETYRY GHSMSDPGT+YRTRDE+Q +R D
Sbjct: 276 GMDILAVYQASKFAKDWCLSGKGPLVLEYETYRYGGHSMSDPGTTYRTRDEIQHMRSKND 335
Query: 182 PITSFKEKVINNQLVTPDQLKEIDAKVRKETDEASKQAKA--DPEIPIEELSGDIYYSNL 355
PI K +I+ + T ++K D RK DE + A A PE + L D+Y
Sbjct: 336 PIAGLKMHLIDLGIATEAEVKAYDKSARKYVDEQVELADAAPPPEAKLSILFEDVYVKGT 395
Query: 356 E-PFIRGTHP 382
E P +RG P
Sbjct: 396 ETPTLRGRIP 405
>UniRef50_Q1EGI2 Cluster: Pyruvate dehydrogenase E1 alpha subunit;
n=6; Spirotrichea|Rep: Pyruvate dehydrogenase E1 alpha
subunit - Euplotes sp. BB-2004
Length = 389
Score = 123 bits (297), Expect = 3e-27
Identities = 60/123 (48%), Positives = 79/123 (64%), Gaps = 2/123 (1%)
Frame = +2
Query: 8 DVIATREATKFAIDYCTSGKGPLLIEMETYRYSGHSMSDPGTSYRTRDEVQEVRQTRDPI 187
+V A RE K+ YCT GKGPL E++TYRY GHSMSDPG +YRTR+EV E R+T+DPI
Sbjct: 254 NVFAVRELYKWGKKYCTDGKGPLFFELQTYRYHGHSMSDPGITYRTREEVNEYRKTQDPI 313
Query: 188 TSFKEKVINNQLVTPDQLKEIDAKVRKETDEASKQAKADPEIPIEELSGDIY--YSNLEP 361
K+ ++ + + T LKEID ++R DE +Q K DP EEL +IY +P
Sbjct: 314 LLVKKWILEHDIATEKYLKEIDKEIRARIDEEVEQIKNDPMPAPEELMTEIYEGQETEKP 373
Query: 362 FIR 370
+IR
Sbjct: 374 YIR 376
>UniRef50_Q4QDQ1 Cluster: Pyruvate dehydrogenase E1 component alpha
subunit, putative; n=5; Euglenozoa|Rep: Pyruvate
dehydrogenase E1 component alpha subunit, putative -
Leishmania major
Length = 378
Score = 120 bits (288), Expect = 3e-26
Identities = 50/114 (43%), Positives = 79/114 (69%)
Frame = +2
Query: 2 GMDVIATREATKFAIDYCTSGKGPLLIEMETYRYSGHSMSDPGTSYRTRDEVQEVRQTRD 181
GMDV+A +E T++A DYC SGKGP+++E++ YRY GHSMSDP YRT+ ++Q V+Q RD
Sbjct: 247 GMDVLAVQEGTRYARDYCMSGKGPIVMELDCYRYMGHSMSDPDNQYRTKSDIQHVKQERD 306
Query: 182 PITSFKEKVINNQLVTPDQLKEIDAKVRKETDEASKQAKADPEIPIEELSGDIY 343
I +E + ++T D++ +++ V+KE D+ ++A+ P ++EL DIY
Sbjct: 307 CIRKMREFMATEGIMTEDEMSKMEKDVKKEVDQDLQKAQKQPMTKLDELFTDIY 360
>UniRef50_Q8H1Y0 Cluster: Pyruvate dehydrogenase E1 component
subunit alpha-2, mitochondrial precursor; n=33; cellular
organisms|Rep: Pyruvate dehydrogenase E1 component
subunit alpha-2, mitochondrial precursor - Arabidopsis
thaliana (Mouse-ear cress)
Length = 393
Score = 117 bits (282), Expect = 2e-25
Identities = 52/114 (45%), Positives = 79/114 (69%)
Frame = +2
Query: 2 GMDVIATREATKFAIDYCTSGKGPLLIEMETYRYSGHSMSDPGTSYRTRDEVQEVRQTRD 181
GMD +A ++A KFA ++ GP+++EM+TYRY GHSMSDPG++YRTRDE+ VRQ RD
Sbjct: 260 GMDALAVKQACKFAKEHALKN-GPIILEMDTYRYHGHSMSDPGSTYRTRDEISGVRQVRD 318
Query: 182 PITSFKEKVINNQLVTPDQLKEIDAKVRKETDEASKQAKADPEIPIEELSGDIY 343
PI ++ ++ + + T +LK+++ ++RKE D+A QAK P EL ++Y
Sbjct: 319 PIERVRKLLLTHDIATEKELKDMEKEIRKEVDDAVAQAKESPIPDASELFTNMY 372
>UniRef50_A2QWB4 Cluster: Catalytic activity: Pyruvate + Lipoamide
<=> S-Acetyldihydrolipoamide + CO2; n=3; Ascomycota|Rep:
Catalytic activity: Pyruvate + Lipoamide <=>
S-Acetyldihydrolipoamide + CO2 - Aspergillus niger
Length = 403
Score = 116 bits (279), Expect = 4e-25
Identities = 56/122 (45%), Positives = 82/122 (67%), Gaps = 2/122 (1%)
Frame = +2
Query: 2 GMDVIATREATKFAIDYCTSGKGPLLIEMETYRYSGHSMSDPGTSYRTRDEVQEVRQTRD 181
GMDV+A A K+ DY G GPLL E +TYRY+GHS+SDPGT+YR+RDEVQ R D
Sbjct: 268 GMDVLAVIAAMKYGKDYVLGGNGPLLYEFQTYRYAGHSVSDPGTAYRSRDEVQAER-AND 326
Query: 182 PITSFKEKVINNQLVTPDQLKEIDAKVRKETDEASKQAK--ADPEIPIEELSGDIYYSNL 355
PIT+++EK+I +++ D +K +D ++R + D +++A+ A+P + + L DIY
Sbjct: 327 PITTYREKMIEWGVLSEDDVKTMDKEIRSKVDREAQEAEKMAEPPLNSDVLFEDIYVRGS 386
Query: 356 EP 361
EP
Sbjct: 387 EP 388
>UniRef50_O96865 Cluster: Pyruvate dehydrogenase E1 alpha subunit;
n=2; Trypanosoma cruzi|Rep: Pyruvate dehydrogenase E1
alpha subunit - Trypanosoma cruzi
Length = 378
Score = 115 bits (276), Expect = 1e-24
Identities = 48/114 (42%), Positives = 80/114 (70%)
Frame = +2
Query: 2 GMDVIATREATKFAIDYCTSGKGPLLIEMETYRYSGHSMSDPGTSYRTRDEVQEVRQTRD 181
GMDV+A +E T++A ++C SGKGP+++E ++YRY GHSMSDP + YR + ++Q+VR+TRD
Sbjct: 247 GMDVLAVQEGTRWAKEWCLSGKGPIVLEFDSYRYVGHSMSDPDSQYRKKSDIQDVRKTRD 306
Query: 182 PITSFKEKVINNQLVTPDQLKEIDAKVRKETDEASKQAKADPEIPIEELSGDIY 343
I K+ ++ ++T +++K+++ V+KE D+ + A+ P EL DIY
Sbjct: 307 CIHKMKDFMLEEGIMTDEEMKKLEKDVKKEVDQQLQPAEKQKPTPRSELFTDIY 360
>UniRef50_Q9R9N5 Cluster: Pyruvate dehydrogenase E1 component
subunit alpha; n=62; Bacteria|Rep: Pyruvate
dehydrogenase E1 component subunit alpha - Rhizobium
meliloti (Sinorhizobium meliloti)
Length = 348
Score = 111 bits (268), Expect = 9e-24
Identities = 53/113 (46%), Positives = 76/113 (67%)
Frame = +2
Query: 2 GMDVIATREATKFAIDYCTSGKGPLLIEMETYRYSGHSMSDPGTSYRTRDEVQEVRQTRD 181
GMDV A + A A+++C SGKGP+++EM TYRY GHSMSDP YR++DEVQ++R D
Sbjct: 235 GMDVRAVKAAADEAVEHCRSGKGPIILEMLTYRYRGHSMSDP-AKYRSKDEVQKMRSEHD 293
Query: 182 PITSFKEKVINNQLVTPDQLKEIDAKVRKETDEASKQAKADPEIPIEELSGDI 340
PI K ++ + T D+LK+ID +VR +++ A++DPE + EL DI
Sbjct: 294 PIEQVKARLTDKGWATEDELKQIDKEVRDIVADSADFAQSDPEPDVSELYTDI 346
>UniRef50_Q5FNM5 Cluster: Pyruvate dehydrogenase E1 component alpha
subunit; n=4; Bacteria|Rep: Pyruvate dehydrogenase E1
component alpha subunit - Gluconobacter oxydans
(Gluconobacter suboxydans)
Length = 334
Score = 108 bits (260), Expect = 8e-23
Identities = 53/113 (46%), Positives = 75/113 (66%)
Frame = +2
Query: 2 GMDVIATREATKFAIDYCTSGKGPLLIEMETYRYSGHSMSDPGTSYRTRDEVQEVRQTRD 181
GMD+ A EA + A++YC SGKGP L+EMETYRY GHSMSDP YR R EV+E+R+TRD
Sbjct: 220 GMDIFAVHEAAQEAMEYCRSGKGPFLLEMETYRYRGHSMSDP-AKYRQRAEVEEMRRTRD 278
Query: 182 PITSFKEKVINNQLVTPDQLKEIDAKVRKETDEASKQAKADPEIPIEELSGDI 340
PI + K +++ + + K+I+ V+ +A++ A+ PE + EL DI
Sbjct: 279 PIETLKAEMLRSG-IEESVFKDIETDVKAIVADATEFAQTSPEPDVSELWTDI 330
>UniRef50_Q23KL2 Cluster: Pyruvate dehydrogenase E1 component; n=5;
Intramacronucleata|Rep: Pyruvate dehydrogenase E1
component - Tetrahymena thermophila SB210
Length = 429
Score = 102 bits (245), Expect = 6e-21
Identities = 52/124 (41%), Positives = 73/124 (58%)
Frame = +2
Query: 2 GMDVIATREATKFAIDYCTSGKGPLLIEMETYRYSGHSMSDPGTSYRTRDEVQEVRQTRD 181
G + +E KFA Y GPL IE+ TYRY GHSMSD GT+YRT++E++E RQ +D
Sbjct: 293 GNNYFHVKEGFKFAKQYALE-HGPLFIELRTYRYHGHSMSDSGTTYRTQEEIKEFRQKKD 351
Query: 182 PITSFKEKVINNQLVTPDQLKEIDAKVRKETDEASKQAKADPEIPIEELSGDIYYSNLEP 361
I ++ N T +QL+ I + R+ D+A +QA DP EL D+Y +N +
Sbjct: 352 CIQFIANTILQNNFATQEQLEAIQDETREIVDKAVEQALKDPLPDDHELCTDVYINNDKY 411
Query: 362 FIRG 373
+IRG
Sbjct: 412 YIRG 415
>UniRef50_Q4T3C0 Cluster: Chromosome undetermined SCAF10102, whole
genome shotgun sequence; n=1; Tetraodon
nigroviridis|Rep: Chromosome undetermined SCAF10102,
whole genome shotgun sequence - Tetraodon nigroviridis
(Green puffer)
Length = 491
Score = 92.7 bits (220), Expect = 6e-18
Identities = 40/90 (44%), Positives = 62/90 (68%)
Frame = +2
Query: 134 SYRTRDEVQEVRQTRDPITSFKEKVINNQLVTPDQLKEIDAKVRKETDEASKQAKADPEI 313
SYRTRDE+QEVR DPI+ K++++ N + + ++ KEID +RKE +EA++ +DPE
Sbjct: 401 SYRTRDEIQEVRSKSDPISMLKDRMLGNNMASVEEFKEIDISIRKEVEEAAQFCTSDPEP 460
Query: 314 PIEELSGDIYYSNLEPFIRGTHPGAQLQHI 403
P+E+L I+ +N +RGTHP A L+ +
Sbjct: 461 PLEDLCNHIFCNNPPLGVRGTHPWAVLKSV 490
>UniRef50_Q4WHM5 Cluster: Pyruvate dehydrogenase E1 component alpha
subunit, putative; n=1; Aspergillus fumigatus|Rep:
Pyruvate dehydrogenase E1 component alpha subunit,
putative - Aspergillus fumigatus (Sartorya fumigata)
Length = 360
Score = 92.7 bits (220), Expect = 6e-18
Identities = 46/113 (40%), Positives = 70/113 (61%), Gaps = 2/113 (1%)
Frame = +2
Query: 29 ATKFAIDYCTSGKGPLLIEMETYRYSGHSMSDPGTSYRTRDEVQEVRQTRDPITSFKEKV 208
A K ++ +G GPL+ E TYRY+GHSMSDPG YRTR E++ R + DP+++F+ ++
Sbjct: 236 AVKHGREFIRAGNGPLVYEYVTYRYAGHSMSDPGVGYRTRGELKAERAS-DPVSNFRAQL 294
Query: 209 INNQLVTPDQLKEIDAKVRKETDE--ASKQAKADPEIPIEELSGDIYYSNLEP 361
I+ ++T D+ K ID VRK+ + A + +PE ++ L DIY EP
Sbjct: 295 IDWGIITEDEAKTIDKNVRKKVNHEVAEAEKMPEPEPRLDVLFQDIYVRGSEP 347
>UniRef50_A7CXZ4 Cluster: Pyruvate dehydrogenase; n=1; Opitutaceae
bacterium TAV2|Rep: Pyruvate dehydrogenase - Opitutaceae
bacterium TAV2
Length = 365
Score = 91.1 bits (216), Expect = 2e-17
Identities = 41/120 (34%), Positives = 70/120 (58%)
Frame = +2
Query: 2 GMDVIATREATKFAIDYCTSGKGPLLIEMETYRYSGHSMSDPGTSYRTRDEVQEVRQTRD 181
G D+ R + + P ++E++TYRY GHS++DP +YRTRDE++E R+T+D
Sbjct: 234 GHDLYEVRAKMHALLTRAREEQKPAVVEIDTYRYRGHSVADPDKTYRTRDEIEEYRKTKD 293
Query: 182 PITSFKEKVINNQLVTPDQLKEIDAKVRKETDEASKQAKADPEIPIEELSGDIYYSNLEP 361
PI F++ ++ +++T ++EID R E D A+ A+A P ++ D+Y+ P
Sbjct: 294 PINLFQQTLLAEKVLTDALIEEIDTAARAEADHAADFAEASPFPTPADIQTDVYWEADNP 353
>UniRef50_O66112 Cluster: Pyruvate dehydrogenase E1 component
subunit alpha; n=38; Proteobacteria|Rep: Pyruvate
dehydrogenase E1 component subunit alpha - Zymomonas
mobilis
Length = 354
Score = 90.2 bits (214), Expect = 3e-17
Identities = 45/113 (39%), Positives = 72/113 (63%)
Frame = +2
Query: 2 GMDVIATREATKFAIDYCTSGKGPLLIEMETYRYSGHSMSDPGTSYRTRDEVQEVRQTRD 181
GMDV+ R A A+D+ +GKGP+++EM+TYRY GHSMSDP YR+R+EV ++++ D
Sbjct: 239 GMDVLEVRGAATVAVDWVQAGKGPIILEMKTYRYRGHSMSDP-ARYRSREEVNDMKENHD 297
Query: 182 PITSFKEKVINNQLVTPDQLKEIDAKVRKETDEASKQAKADPEIPIEELSGDI 340
P+ + K+ + V +L ++D +R++ EA+ A+ P EEL +I
Sbjct: 298 PLDNLKKDLFAAG-VPEAELVKLDEDIRQQVKEAADFAEKAPLPADEELYTNI 349
>UniRef50_Q8TA29 Cluster: Putative pyruvate dehydrogenase; n=1;
Heterodera glycines|Rep: Putative pyruvate dehydrogenase
- Heterodera glycines (Soybean cyst nematode worm)
Length = 132
Score = 87.4 bits (207), Expect = 2e-16
Identities = 41/78 (52%), Positives = 57/78 (73%)
Frame = +2
Query: 143 TRDEVQEVRQTRDPITSFKEKVINNQLVTPDQLKEIDAKVRKETDEASKQAKADPEIPIE 322
TRDE+QEVR++RDPITSFK++++ LVT ++LK+ID KVR+E DEA K A +D +P E
Sbjct: 1 TRDEIQEVRKSRDPITSFKDRIVTAGLVTEEELKDIDKKVRQEVDEAVKVALSDEVLPPE 60
Query: 323 ELSGDIYYSNLEPFIRGT 376
L D+Y + +RGT
Sbjct: 61 TLFSDLYANTPPLAVRGT 78
>UniRef50_A6Q3I6 Cluster: Pyruvate/2-oxoglutarate dehydrogenase
complex, E1 component, alpha subunit; n=2; unclassified
Epsilonproteobacteria|Rep: Pyruvate/2-oxoglutarate
dehydrogenase complex, E1 component, alpha subunit -
Nitratiruptor sp. (strain SB155-2)
Length = 323
Score = 86.6 bits (205), Expect = 4e-16
Identities = 48/114 (42%), Positives = 65/114 (57%)
Frame = +2
Query: 2 GMDVIATREATKFAIDYCTSGKGPLLIEMETYRYSGHSMSDPGTSYRTRDEVQEVRQTRD 181
GMDV +A A +Y +G GP IE ETYRY GHSMSD G YR+ +E+ E+ ++RD
Sbjct: 203 GMDVCEVYKAVTEAKEYLENGLGPYFIEAETYRYEGHSMSDNG-KYRSEEEM-EIFKSRD 260
Query: 182 PITSFKEKVINNQLVTPDQLKEIDAKVRKETDEASKQAKADPEIPIEELSGDIY 343
PI K++ I +V E D +V +E EA + A PE + EL D+Y
Sbjct: 261 PIEKLKKEAIALGIVEESYFDETDKRVEQEIAEAIEFAANSPEPDLSELYEDVY 314
>UniRef50_Q1XDM0 Cluster: Pyruvate dehydrogenase E1 component
subunit alpha; n=52; cellular organisms|Rep: Pyruvate
dehydrogenase E1 component subunit alpha - Porphyra
yezoensis
Length = 346
Score = 86.6 bits (205), Expect = 4e-16
Identities = 46/117 (39%), Positives = 68/117 (58%)
Frame = +2
Query: 2 GMDVIATREATKFAIDYCTSGKGPLLIEMETYRYSGHSMSDPGTSYRTRDEVQEVRQTRD 181
GMDV+A R+A K A+ G GP LIE TYR+ GHS++DP R+R E +E RD
Sbjct: 232 GMDVLAVRQAAKQAVQRARQGDGPTLIEALTYRFRGHSLADP-DELRSRQE-KEAWVARD 289
Query: 182 PITSFKEKVINNQLVTPDQLKEIDAKVRKETDEASKQAKADPEIPIEELSGDIYYSN 352
PI K+ +++N++ +L EI V+ E ++A K A + PE + EL ++ N
Sbjct: 290 PIKKLKKYILDNEIANIGELNEIQNAVKTELEQAVKFAISSPEPNMSELKRYLFADN 346
>UniRef50_A4VXG8 Cluster: Pyruvate/2-oxoglutarate dehydrogenase
complex, dehydrogenase (E1) component, eukaryotic type,
alpha subunit; n=40; Streptococcus|Rep:
Pyruvate/2-oxoglutarate dehydrogenase complex,
dehydrogenase (E1) component, eukaryotic type, alpha
subunit - Streptococcus suis (strain 05ZYH33)
Length = 337
Score = 85.4 bits (202), Expect = 9e-16
Identities = 40/114 (35%), Positives = 72/114 (63%)
Frame = +2
Query: 2 GMDVIATREATKFAIDYCTSGKGPLLIEMETYRYSGHSMSDPGTSYRTRDEVQEVRQTRD 181
G DVIA E + I+Y +GKGP ++E+E+YR+ GHS +D G YRT++EV E + +D
Sbjct: 224 GNDVIAVYEKMQEVIEYVRAGKGPAMVEVESYRWFGHSTADAGV-YRTKEEVNEWK-AKD 281
Query: 182 PITSFKEKVINNQLVTPDQLKEIDAKVRKETDEASKQAKADPEIPIEELSGDIY 343
P+ +++ + N++ T ++L I+A+V ++ + + K A+ P+ I D++
Sbjct: 282 PLKKYRKYLTENKIATDEELDAIEAQVAEQVEASVKFAQESPDPDISVAYEDVF 335
>UniRef50_A3VIE7 Cluster: Tpp-dependent acetoin dehydrogenase e1
alpha-subunit; n=2; Rhodobacterales|Rep: Tpp-dependent
acetoin dehydrogenase e1 alpha-subunit - Rhodobacterales
bacterium HTCC2654
Length = 335
Score = 85.4 bits (202), Expect = 9e-16
Identities = 37/115 (32%), Positives = 68/115 (59%), Gaps = 1/115 (0%)
Frame = +2
Query: 2 GMDVIATREATKFAIDYCTSGKGPLLIEMETYRYSGHSMSDPGTS-YRTRDEVQEVRQTR 178
G DV+A E T+ + C G+GP +E+ETYRY GH + D YR++DE ++ R+ R
Sbjct: 219 GQDVLAVNELTQKLVARCRKGEGPFFVELETYRYHGHHVGDINREYYRSKDEEKDWRENR 278
Query: 179 DPITSFKEKVINNQLVTPDQLKEIDAKVRKETDEASKQAKADPEIPIEELSGDIY 343
DPI F+ +++ + + ++++ ++A++ K+ +A A+A P E+ +Y
Sbjct: 279 DPIIRFRAYLVDQGIASEEEIEAMNAEIEKDATDAVAYAEAAPYPDASEVDMHVY 333
>UniRef50_Q1AZ54 Cluster: Pyruvate dehydrogenase; n=1; Rubrobacter
xylanophilus DSM 9941|Rep: Pyruvate dehydrogenase -
Rubrobacter xylanophilus (strain DSM 9941 / NBRC 16129)
Length = 325
Score = 84.6 bits (200), Expect = 2e-15
Identities = 42/102 (41%), Positives = 62/102 (60%)
Frame = +2
Query: 2 GMDVIATREATKFAIDYCTSGKGPLLIEMETYRYSGHSMSDPGTSYRTRDEVQEVRQTRD 181
G DV+A EA A++ G+GP LIE TYR+ GH DP T YR R+EV+ R+ RD
Sbjct: 212 GQDVVAVYEAVSRAVERARRGEGPSLIEAMTYRFRGHYEGDPDT-YRDREEVERWRKERD 270
Query: 182 PITSFKEKVINNQLVTPDQLKEIDAKVRKETDEASKQAKADP 307
PI ++ + L + L++I A+V++E DEA+++A P
Sbjct: 271 PILLLANRLRSEGLASEQDLEQIRARVQREVDEAAEEALGAP 312
>UniRef50_Q42066 Cluster: Pyruvate dehydrogenase E1 componen; n=5;
Eukaryota|Rep: Pyruvate dehydrogenase E1 componen -
Arabidopsis thaliana (Mouse-ear cress)
Length = 127
Score = 83.4 bits (197), Expect = 4e-15
Identities = 37/67 (55%), Positives = 47/67 (70%)
Frame = +2
Query: 2 GMDVIATREATKFAIDYCTSGKGPLLIEMETYRYSGHSMSDPGTSYRTRDEVQEVRQTRD 181
GMD ++A KF + KGP+++EM+TYRY GHSMS PG++YRTRDE+ VRQ RD
Sbjct: 57 GMDAFPVKQACKFPKQHXXE-KGPIILEMDTYRYHGHSMSXPGSTYRTRDEISXVRQERD 115
Query: 182 PITSFKE 202
PI KE
Sbjct: 116 PIERIKE 122
>UniRef50_A5UVY9 Cluster: Pyruvate dehydrogenase; n=2;
Roseiflexus|Rep: Pyruvate dehydrogenase - Roseiflexus
sp. RS-1
Length = 334
Score = 81.8 bits (193), Expect = 1e-14
Identities = 41/114 (35%), Positives = 66/114 (57%)
Frame = +2
Query: 2 GMDVIATREATKFAIDYCTSGKGPLLIEMETYRYSGHSMSDPGTSYRTRDEVQEVRQTRD 181
G DV A EA A++ SG GP L+E +TYR+ H+ +D YR +EV E + RD
Sbjct: 221 GNDVFAVYEAAHQAMERARSGGGPTLLECKTYRFRPHTSADDDRRYRKPEEV-EAWRARD 279
Query: 182 PITSFKEKVINNQLVTPDQLKEIDAKVRKETDEASKQAKADPEIPIEELSGDIY 343
PI F+ ++ + ++T D+++ + +VR E D A+ A A P P+E ++ +Y
Sbjct: 280 PIKRFEHYLVEHGIITHDEIEAMRREVRAEVDAATDAALAAPWPPVESIADHVY 333
>UniRef50_A5UU15 Cluster: Pyruvate dehydrogenase; n=3; Chloroflexi
(class)|Rep: Pyruvate dehydrogenase - Roseiflexus sp.
RS-1
Length = 350
Score = 80.2 bits (189), Expect = 3e-14
Identities = 37/103 (35%), Positives = 63/103 (61%)
Frame = +2
Query: 2 GMDVIATREATKFAIDYCTSGKGPLLIEMETYRYSGHSMSDPGTSYRTRDEVQEVRQTRD 181
G DV+ REA+ A+++ SGKGP+L+E TYR+ GHS D YRT+++++ R+ D
Sbjct: 225 GNDVLVMREASLRAVEHARSGKGPVLLEAMTYRFRGHSAQDT-QKYRTKEDIERHRR-ND 282
Query: 182 PITSFKEKVINNQLVTPDQLKEIDAKVRKETDEASKQAKADPE 310
PI ++ ++N + T Q+++ID + + + A + A PE
Sbjct: 283 PIVRYRTLLLNEGIATEQQIRDIDRMIDDQVEAAVRFADESPE 325
>UniRef50_Q74AD3 Cluster: Dehydrogenase complex, E1 component, alpha
subunit; n=5; Geobacter|Rep: Dehydrogenase complex, E1
component, alpha subunit - Geobacter sulfurreducens
Length = 325
Score = 78.6 bits (185), Expect = 1e-13
Identities = 43/114 (37%), Positives = 66/114 (57%)
Frame = +2
Query: 2 GMDVIATREATKFAIDYCTSGKGPLLIEMETYRYSGHSMSDPGTSYRTRDEVQEVRQTRD 181
GMDV+A EA K+ ++ P LIE TYR+ GHSM+DPG YR+ EV E+ ++RD
Sbjct: 213 GMDVMAVHEAVKWGAEWVREHSRPYLIEAMTYRFRGHSMADPG-KYRSAAEV-ELWKSRD 270
Query: 182 PITSFKEKVINNQLVTPDQLKEIDAKVRKETDEASKQAKADPEIPIEELSGDIY 343
PI +F+++++ + T +L + K R +A A+ P +E+ DIY
Sbjct: 271 PIPNFEKRLVEEGIATEAELAAVLEKCRGVVADAVAFAEESPWPEDDEVYSDIY 324
>UniRef50_Q3J9C5 Cluster: Dehydrogenase, E1 component; n=3;
Proteobacteria|Rep: Dehydrogenase, E1 component -
Nitrosococcus oceani (strain ATCC 19707 / NCIMB 11848)
Length = 339
Score = 78.2 bits (184), Expect = 1e-13
Identities = 45/121 (37%), Positives = 68/121 (56%), Gaps = 1/121 (0%)
Frame = +2
Query: 2 GMDVIATREATKFAIDYCTSGKGPLLIEMETYRYSGHSMSDPGTSYRTRDEVQEVRQTRD 181
G D+ EA + AI + SG GP +E TYRY GHSMSD G +YR+++EV E Q RD
Sbjct: 210 GQDIEVVMEAAQSAIAHVRSGAGPYFLEFLTYRYRGHSMSDAG-AYRSKEEVAEWMQ-RD 267
Query: 182 PITSFKEKVINNQLVTPDQLKEIDAKVRKETDEASKQ-AKADPEIPIEELSGDIYYSNLE 358
PI +++I +T ++ K ++ V+ E D Q A+ PE + +L+ + N +
Sbjct: 268 PIQILAKRLIEAGELTEEEFKAMEQAVQSEIDNDIIQFAEESPEPKVADLAKYVLEDNPD 327
Query: 359 P 361
P
Sbjct: 328 P 328
>UniRef50_Q1KSF1 Cluster: Apicoplast pyruvate dehydrogenase E1 alpha
subunit; n=1; Toxoplasma gondii|Rep: Apicoplast pyruvate
dehydrogenase E1 alpha subunit - Toxoplasma gondii
Length = 635
Score = 77.8 bits (183), Expect = 2e-13
Identities = 43/114 (37%), Positives = 63/114 (55%)
Frame = +2
Query: 2 GMDVIATREATKFAIDYCTSGKGPLLIEMETYRYSGHSMSDPGTSYRTRDEVQEVRQTRD 181
GMDV+A R A + AID G+GP LIE TYR+ GHS++DP + +E RD
Sbjct: 467 GMDVLAVRGAARRAIDRARRGEGPTLIEALTYRFRGHSVADPDEMRAVKQ--KEAWVVRD 524
Query: 182 PITSFKEKVINNQLVTPDQLKEIDAKVRKETDEASKQAKADPEIPIEELSGDIY 343
PI SF+E++ + + + AKV+ D+A K A+ PE ++E I+
Sbjct: 525 PIKSFEEELKRLGYASDETIAATRAKVKAVVDDAVKFAETSPEPDVQECGQFIF 578
>UniRef50_Q1NYU1 Cluster: Pyruvate dehydrogenase E1 component alpha
subunit; n=1; Candidatus Sulcia muelleri str. Hc
(Homalodisca coagulata)|Rep: Pyruvate dehydrogenase E1
component alpha subunit - Candidatus Sulcia muelleri
str. Hc (Homalodisca coagulata)
Length = 167
Score = 77.4 bits (182), Expect = 2e-13
Identities = 43/122 (35%), Positives = 65/122 (53%)
Frame = +2
Query: 2 GMDVIATREATKFAIDYCTSGKGPLLIEMETYRYSGHSMSDPGTSYRTRDEVQEVRQTRD 181
GMD + E AI +G GP +++ TYRY GHSM+D T YR++ EV E + RD
Sbjct: 44 GMDPLKIYEHAYNAISRARNGNGPTFLDILTYRYRGHSMTDAET-YRSKKEVNE-SKNRD 101
Query: 182 PITSFKEKVINNQLVTPDQLKEIDAKVRKETDEASKQAKADPEIPIEELSGDIYYSNLEP 361
PI K+ ++ N++VT L ++ K+ +E K A+ IE+L +Y P
Sbjct: 102 PILLIKKFILKNKIVTEKVLNSFQDEINKKINECVKFAELSDSTNIEKLYSVVYNQKDYP 161
Query: 362 FI 367
F+
Sbjct: 162 FL 163
>UniRef50_Q18CB6 Cluster: Acetoin:2,6-dichlorophenolindophenol
oxidoreductase alpha subunit; n=2; Clostridium
difficile|Rep: Acetoin:2,6-dichlorophenolindophenol
oxidoreductase alpha subunit - Clostridium difficile
(strain 630)
Length = 322
Score = 77.4 bits (182), Expect = 2e-13
Identities = 42/114 (36%), Positives = 63/114 (55%)
Frame = +2
Query: 2 GMDVIATREATKFAIDYCTSGKGPLLIEMETYRYSGHSMSDPGTSYRTRDEVQEVRQTRD 181
G + I E + A + C G+GP+LIE TYR+ GHS SD YRT++E+ E + +D
Sbjct: 209 GYNPIEVYETVQKAAEKCRRGEGPVLIESRTYRWLGHSKSDANV-YRTKEEI-ESWKAKD 266
Query: 182 PITSFKEKVINNQLVTPDQLKEIDAKVRKETDEASKQAKADPEIPIEELSGDIY 343
PI K +I N L D+L +I ++ ++A + A+ P IE L D+Y
Sbjct: 267 PIEFLKNYLIENNLSNEDELDKIQEFAKQSIEDAVEFAQNSPNPKIESLLEDVY 320
>UniRef50_A0LTQ9 Cluster: Pyruvate dehydrogenase; n=1; Acidothermus
cellulolyticus 11B|Rep: Pyruvate dehydrogenase -
Acidothermus cellulolyticus (strain ATCC 43068 / 11B)
Length = 342
Score = 74.5 bits (175), Expect = 2e-12
Identities = 43/110 (39%), Positives = 65/110 (59%), Gaps = 2/110 (1%)
Frame = +2
Query: 2 GMDVIATREATKFAIDYCTSGKGPLLIEMETYRYSGHSMSDPGTSYRTRDEVQEVRQTRD 181
G DV A + + +I C +G GP+LIE TYR GHS +DPGT YR ++EV E RD
Sbjct: 223 GNDVAAVFDVARRSIAECRTGGGPVLIEALTYRQGGHSRADPGT-YRPKEEV-EAWLARD 280
Query: 182 PITSFKEKVINNQLVTPDQLKEIDAKVRKETDEASKQAK--ADPEIPIEE 325
P+T ++E ++ + L EI+A+ E D A ++A+ A P++ + E
Sbjct: 281 PVTCYREHLLASG-YPAGTLDEIEARATAEVDRAVEEARTAAAPDVSLVE 329
>UniRef50_A6DTS3 Cluster: Dehydrogenase complex, E1 component, alpha
subunit; n=1; Lentisphaera araneosa HTCC2155|Rep:
Dehydrogenase complex, E1 component, alpha subunit -
Lentisphaera araneosa HTCC2155
Length = 320
Score = 73.7 bits (173), Expect = 3e-12
Identities = 40/114 (35%), Positives = 65/114 (57%)
Frame = +2
Query: 2 GMDVIATREATKFAIDYCTSGKGPLLIEMETYRYSGHSMSDPGTSYRTRDEVQEVRQTRD 181
GM++ A+ +A I C P L+ + TYRY GHS+SD G YRT+DEV+ ++ +D
Sbjct: 208 GMNLEASYKAFGEIIADCKKNSRPALVNVTTYRYQGHSVSDAGL-YRTKDEVKCWKE-KD 265
Query: 182 PITSFKEKVINNQLVTPDQLKEIDAKVRKETDEASKQAKADPEIPIEELSGDIY 343
PI SF + + + + K +D +++ E +A AK P P++EL+ +Y
Sbjct: 266 PINSFYKSMEEQGWIDEEGYKALDKEMKAEVKDALDFAKESPWPPMDELTNHVY 319
>UniRef50_Q8ZUR8 Cluster: Pyruvate dehydrogenase E1 alpha subunit;
n=3; Pyrobaculum|Rep: Pyruvate dehydrogenase E1 alpha
subunit - Pyrobaculum aerophilum
Length = 372
Score = 73.7 bits (173), Expect = 3e-12
Identities = 39/115 (33%), Positives = 67/115 (58%), Gaps = 1/115 (0%)
Frame = +2
Query: 2 GMDVIATREATKFAIDYCTSGKGPLLIEMETYRYSGHSMSD-PGTSYRTRDEVQEVRQTR 178
GMD++A + +A++ G+ P L+E YR+ H+ +D P T YR EV+E R+
Sbjct: 246 GMDLLAVVKTAMWAVEKARRGE-PTLVEYVMYRFGPHTTADDPLTKYRDPKEVEEYRRW- 303
Query: 179 DPITSFKEKVINNQLVTPDQLKEIDAKVRKETDEASKQAKADPEIPIEELSGDIY 343
DP+ ++ +I + + +K I + +E EA+K+A+A P++P EEL D+Y
Sbjct: 304 DPLARLEKFLIRQGIYSEGDVKTIWEEAEREVKEAAKEAEALPDVPAEELINDVY 358
>UniRef50_Q9LPL5 Cluster: Branched-chain alpha keto-acid
dehydrogenase E1-alpha subunit; n=13; Magnoliophyta|Rep:
Branched-chain alpha keto-acid dehydrogenase E1-alpha
subunit - Arabidopsis thaliana (Mouse-ear cress)
Length = 472
Score = 72.9 bits (171), Expect = 5e-12
Identities = 37/114 (32%), Positives = 63/114 (55%)
Frame = +2
Query: 2 GMDVIATREATKFAIDYCTSGKGPLLIEMETYRYSGHSMSDPGTSYRTRDEVQEVRQTRD 181
G D +A A + A + + + P+LIEM TYR HS SD T YR DE+Q + +R+
Sbjct: 328 GNDALAVYSAVRSAREMAVTEQRPVLIEMMTYRVGHHSTSDDSTKYRAADEIQYWKMSRN 387
Query: 182 PITSFKEKVINNQLVTPDQLKEIDAKVRKETDEASKQAKADPEIPIEELSGDIY 343
P+ F++ V +N + + ++ + RK+ +A + A+ + P+ EL D+Y
Sbjct: 388 PVNRFRKWVEDNGWWSEEDESKLRSNARKQLLQAIQAAEKWEKQPLTELFNDVY 441
>UniRef50_Q0W151 Cluster: Pyruvate dehydrogenase complex E1,
transketolase alpha subunit; n=1; uncultured
methanogenic archaeon RC-I|Rep: Pyruvate dehydrogenase
complex E1, transketolase alpha subunit - Uncultured
methanogenic archaeon RC-I
Length = 359
Score = 72.9 bits (171), Expect = 5e-12
Identities = 37/114 (32%), Positives = 63/114 (55%)
Frame = +2
Query: 2 GMDVIATREATKFAIDYCTSGKGPLLIEMETYRYSGHSMSDPGTSYRTRDEVQEVRQTRD 181
GMDV+A+ K +D +G+GP IE YR+ H+ SD YR++ EV+++R+ D
Sbjct: 225 GMDVLASYVIVKDLLDRARNGEGPAFIEAICYRFGPHTTSDNPDLYRSKGEVEKIRKETD 284
Query: 182 PITSFKEKVINNQLVTPDQLKEIDAKVRKETDEASKQAKADPEIPIEELSGDIY 343
PI F+ ++N L D+ + ++ D+A+K+A+ P EEL ++
Sbjct: 285 PIDRFRNYLVNKGLWDIDKETRLHDEMDALIDKAAKEAEQAPAPEFEELFKHVF 338
>UniRef50_A7HBV0 Cluster: 3-methyl-2-oxobutanoate dehydrogenase;
n=4; Cystobacterineae|Rep: 3-methyl-2-oxobutanoate
dehydrogenase - Anaeromyxobacter sp. Fw109-5
Length = 399
Score = 72.5 bits (170), Expect = 7e-12
Identities = 41/115 (35%), Positives = 64/115 (55%), Gaps = 1/115 (0%)
Frame = +2
Query: 2 GMDVIATREATKFAIDYCTSGKGPLLIEMETYRYSGHSMSDPGTSYRTRDEVQEVRQTRD 181
G D++A AT+ A + +G+GP L+E TYR GHS SD +YR E+ E + RD
Sbjct: 254 GNDLLAVHAATRRARERAEAGEGPTLLECVTYRVEGHSTSDDPRAYRPA-ELVEPWKKRD 312
Query: 182 PITSFKEKVINNQLVTPDQLKEIDAKVRKETDEASKQAKA-DPEIPIEELSGDIY 343
PI + ++ + + + I A+VR+E K+A+A P+ P+E L D+Y
Sbjct: 313 PILRMRRYLVRRGALAEAEDERIRAQVREELQRVLKEAEAFAPKPPLESLFEDVY 367
>UniRef50_Q4QC52 Cluster: 2-oxoisovalerate dehydrogenase alpha
subunit, putative; n=3; Leishmania|Rep: 2-oxoisovalerate
dehydrogenase alpha subunit, putative - Leishmania major
Length = 479
Score = 72.5 bits (170), Expect = 7e-12
Identities = 36/114 (31%), Positives = 59/114 (51%)
Frame = +2
Query: 2 GMDVIATREATKFAIDYCTSGKGPLLIEMETYRYSGHSMSDPGTSYRTRDEVQEVRQTRD 181
G+D +A + A + + P+L+E TYR S HS SD T+YR+RDE++ +T
Sbjct: 336 GLDALAVYHTVRKAREMILNSHRPVLVEALTYRLSHHSTSDDSTAYRSRDEIEHFAETFS 395
Query: 182 PITSFKEKVINNQLVTPDQLKEIDAKVRKETDEASKQAKADPEIPIEELSGDIY 343
PI F+ V TP+Q +E+ + R E ++ + P P+ L D++
Sbjct: 396 PIERFEHFVTARGWWTPEQSREVVERTRSEVLSELRRQEKLPAWPVSTLCDDVF 449
>UniRef50_Q1IQR3 Cluster: Dehydrogenase, E1 component; n=1;
Acidobacteria bacterium Ellin345|Rep: Dehydrogenase, E1
component - Acidobacteria bacterium (strain Ellin345)
Length = 736
Score = 72.1 bits (169), Expect = 9e-12
Identities = 40/120 (33%), Positives = 61/120 (50%)
Frame = +2
Query: 2 GMDVIATREATKFAIDYCTSGKGPLLIEMETYRYSGHSMSDPGTSYRTRDEVQEVRQTRD 181
G +V+ + A K AIDY +GKGP + R HS+SD YR E ++ RD
Sbjct: 253 GTEVLESYRAFKRAIDYIRAGKGPAFVHGHVIRPYSHSLSDDEKLYRPEAERKD-EANRD 311
Query: 182 PITSFKEKVINNQLVTPDQLKEIDAKVRKETDEASKQAKADPEIPIEELSGDIYYSNLEP 361
PIT F + ++ L T +LK++ V E ++S +A P ++ S +Y S L+P
Sbjct: 312 PITKFYKWLVAESLATDKELKDLQTDVDTEVQDSSDRAVEAPIPALDSYSQHLYSSTLDP 371
>UniRef50_A0LSF3 Cluster: Pyruvate dehydrogenase; n=5; Bacteria|Rep:
Pyruvate dehydrogenase - Acidothermus cellulolyticus
(strain ATCC 43068 / 11B)
Length = 375
Score = 71.7 bits (168), Expect = 1e-11
Identities = 45/135 (33%), Positives = 71/135 (52%)
Frame = +2
Query: 2 GMDVIATREATKFAIDYCTSGKGPLLIEMETYRYSGHSMSDPGTSYRTRDEVQEVRQTRD 181
G DVIA REA + A+ + P ++E +YR GHS+ DP YR+++E Q + D
Sbjct: 244 GNDVIACREALRDALRKAREERAPSILEAVSYRLRGHSVVDP-ARYRSKEEAQRL-LAHD 301
Query: 182 PITSFKEKVINNQLVTPDQLKEIDAKVRKETDEASKQAKADPEIPIEELSGDIYYSNLEP 361
P+T+F++++I+ +++ D+ IDA+V D A + A P EL Y L P
Sbjct: 302 PVTAFRQRLIDVGVLSADEAARIDAEVEAAVDAAVEFADNSPHPSPAELFAHAYAHPL-P 360
Query: 362 FIRGTHPGAQLQHIQ 406
+ PG L I+
Sbjct: 361 NMPRALPGDPLLPIE 375
>UniRef50_Q98FT3 Cluster: Acetoin dehydrogenase (TPP-dependent)
alpha chain; n=6; Bacteria|Rep: Acetoin dehydrogenase
(TPP-dependent) alpha chain - Rhizobium loti
(Mesorhizobium loti)
Length = 342
Score = 70.9 bits (166), Expect = 2e-11
Identities = 36/106 (33%), Positives = 60/106 (56%)
Frame = +2
Query: 26 EATKFAIDYCTSGKGPLLIEMETYRYSGHSMSDPGTSYRTRDEVQEVRQTRDPITSFKEK 205
EA+ A++ +G+GP LIE +TYR+ GHS SD YRT++E+++ RDPIT F+ +
Sbjct: 234 EASYRAVERARAGEGPTLIESKTYRHRGHSKSDRNR-YRTKEEIEDWMSNRDPITLFENE 292
Query: 206 VINNQLVTPDQLKEIDAKVRKETDEASKQAKADPEIPIEELSGDIY 343
+ + ++ I + V +E + + AKA P + E +Y
Sbjct: 293 LREFGFIDDKGIEAIRSAVSQEIADGIEFAKASPSPDVSETGNYVY 338
>UniRef50_Q12FH4 Cluster: Pyruvate dehydrogenase; n=37;
Bacteria|Rep: Pyruvate dehydrogenase - Polaromonas sp.
(strain JS666 / ATCC BAA-500)
Length = 337
Score = 70.5 bits (165), Expect = 3e-11
Identities = 40/114 (35%), Positives = 64/114 (56%)
Frame = +2
Query: 2 GMDVIATREATKFAIDYCTSGKGPLLIEMETYRYSGHSMSDPGTSYRTRDEVQEVRQTRD 181
GMDV+A +A + + S P+ +E++TYR+ HSM DP YR + EVQ +TR
Sbjct: 220 GMDVVAVFDAVQRSAQQVRSQGRPVFVELKTYRFRAHSMFDP-ELYRDKAEVQ-AWKTRG 277
Query: 182 PITSFKEKVINNQLVTPDQLKEIDAKVRKETDEASKQAKADPEIPIEELSGDIY 343
PI +F ++ +T D+ +DA + E D A+ A+A P+E+L D++
Sbjct: 278 PIHTFTARLKAQGSLTEDEFLVLDAAAQAEVDAAAAFAEAGTWEPVEDLLRDVH 331
>UniRef50_Q5QUK4 Cluster: Alpha keto acid dehydrogenase complex, E1
component, alpha subunit; n=32; Gammaproteobacteria|Rep:
Alpha keto acid dehydrogenase complex, E1 component,
alpha subunit - Idiomarina loihiensis
Length = 395
Score = 70.1 bits (164), Expect = 4e-11
Identities = 41/114 (35%), Positives = 63/114 (55%)
Frame = +2
Query: 2 GMDVIATREATKFAIDYCTSGKGPLLIEMETYRYSGHSMSDPGTSYRTRDEVQEVRQTRD 181
G DV A +AT+ A P+LIE +YR SGHS SD T YRTRDE + Q +D
Sbjct: 250 GNDVFAVLKATQEARRLAVEENEPVLIEAMSYRMSGHSTSDDPTGYRTRDE-EAGWQAKD 308
Query: 182 PITSFKEKVINNQLVTPDQLKEIDAKVRKETDEASKQAKADPEIPIEELSGDIY 343
P+ ++ + + + D ++E A+V+ + A K+++ P I+EL D+Y
Sbjct: 309 PLERLQKWMTDEGWLDKDHVEEHHAEVKAKVLAALKESEKVPVPHIDELINDVY 362
>UniRef50_Q4DB65 Cluster: 2-oxoisovalerate dehydrogenase alpha
subunit, putative; n=3; Trypanosoma|Rep:
2-oxoisovalerate dehydrogenase alpha subunit, putative -
Trypanosoma cruzi
Length = 431
Score = 69.7 bits (163), Expect = 5e-11
Identities = 39/115 (33%), Positives = 62/115 (53%), Gaps = 1/115 (0%)
Frame = +2
Query: 2 GMDVIATREATKFAIDYCTSGKGPLLIEMETYRYSGHSMSDPGTSYRTRDEVQEVRQTRD 181
G D++A + + A + + P+L+E YR S HS SD T YR+RDEV+
Sbjct: 291 GNDILAVFQTVRKARELIRTTNQPVLVEALLYRSSHHSSSDDSTWYRSRDEVEVFSNLFL 350
Query: 182 PITSFKEKVINNQLVTPDQLKEIDAKVRKET-DEASKQAKADPEIPIEELSGDIY 343
P+ F++ + L TP+Q + + KVR+ET E +Q K P+ P+ + D+Y
Sbjct: 351 PVARFEKYLERKLLWTPEQSRSLSQKVRQETLAELHRQEKL-PKWPVSSMHDDVY 404
>UniRef50_Q72GU1 Cluster: 2-oxoisovalerate dehydrogenase subunit
alpha; n=2; Thermus thermophilus|Rep: 2-oxoisovalerate
dehydrogenase subunit alpha - Thermus thermophilus
(strain HB27 / ATCC BAA-163 / DSM 7039)
Length = 367
Score = 69.7 bits (163), Expect = 5e-11
Identities = 35/114 (30%), Positives = 63/114 (55%)
Frame = +2
Query: 2 GMDVIATREATKFAIDYCTSGKGPLLIEMETYRYSGHSMSDPGTSYRTRDEVQEVRQTRD 181
GMDV+A+ K A++ G+GP L+E+ YRY HS +D + YR ++EV R+ +D
Sbjct: 237 GMDVLASYYVVKEAVERARRGEGPSLVELRVYRYGPHSSADDDSRYRPKEEVAFWRK-KD 295
Query: 182 PITSFKEKVINNQLVTPDQLKEIDAKVRKETDEASKQAKADPEIPIEELSGDIY 343
PI F+ + L + +++ ++R E + K+A+ +P E + D++
Sbjct: 296 PIPRFRRFLEARGLWNEEWEEDVREEIRAELERGLKEAEEAGPVPPEWMFADVF 349
>UniRef50_Q2S150 Cluster: Pyruvate dehydrogenase E1 component, alpha
subunit; n=1; Salinibacter ruber DSM 13855|Rep: Pyruvate
dehydrogenase E1 component, alpha subunit - Salinibacter
ruber (strain DSM 13855)
Length = 470
Score = 69.3 bits (162), Expect = 6e-11
Identities = 40/123 (32%), Positives = 66/123 (53%), Gaps = 1/123 (0%)
Frame = +2
Query: 2 GMDVIATREATKFAIDYCTSGKGPLLIEMETYRYSGHSMSDPGTSYRTRDEVQEVRQTRD 181
GMDV + +A + ++ P L+E+ TYRY GHS++DP YR E+ + RQ++D
Sbjct: 350 GMDVFSVNKAVQDHVENYARNDQPSLLEVRTYRYQGHSITDP-AEYRGEGELDQ-RQSQD 407
Query: 182 PITSFKEKVINNQLVTPDQLKEIDAKVRKETDEASKQAKADPEIPIEE-LSGDIYYSNLE 358
I ++ +++ L T ++ ID +V++ +A A + P EE + DIY
Sbjct: 408 AINRLQDYILDRGLATEADMEAIDEEVKERVKDAIDAAN-EASFPDEEAIYDDIYTQEDY 466
Query: 359 PFI 367
PFI
Sbjct: 467 PFI 469
>UniRef50_P47516 Cluster: Pyruvate dehydrogenase E1 component
subunit alpha; n=5; Mycoplasma|Rep: Pyruvate
dehydrogenase E1 component subunit alpha - Mycoplasma
genitalium
Length = 358
Score = 69.3 bits (162), Expect = 6e-11
Identities = 37/120 (30%), Positives = 66/120 (55%)
Frame = +2
Query: 2 GMDVIATREATKFAIDYCTSGKGPLLIEMETYRYSGHSMSDPGTSYRTRDEVQEVRQTRD 181
G D+IA+ EA + A +Y G GP+LIE +YR H+ SD + YRT+ E +E ++ D
Sbjct: 226 GNDLIASYEAMQDAANYARGGNGPVLIEFFSYRQGPHTTSDDPSIYRTKQEEEEGMKS-D 284
Query: 182 PITSFKEKVINNQLVTPDQLKEIDAKVRKETDEASKQAKADPEIPIEELSGDIYYSNLEP 361
P+ + + + ++ Q +E+ +K+ +E A ++ D + ++E+ D Y L P
Sbjct: 285 PVKRLRNFLFDRSILNQAQEEEMFSKIEQEIQAAYEKMVLDTPVSVDEVF-DYNYQELTP 343
>UniRef50_A4AFX0 Cluster: Acetoin dehydrogenase (TPP-dependent)
alpha chain; n=1; marine actinobacterium PHSC20C1|Rep:
Acetoin dehydrogenase (TPP-dependent) alpha chain -
marine actinobacterium PHSC20C1
Length = 327
Score = 68.9 bits (161), Expect = 8e-11
Identities = 41/103 (39%), Positives = 54/103 (52%)
Frame = +2
Query: 2 GMDVIATREATKFAIDYCTSGKGPLLIEMETYRYSGHSMSDPGTSYRTRDEVQEVRQTRD 181
G DVIA R ATK A++ +G+GP LIE +TYR+SGHS SDP YR +EV+ RD
Sbjct: 217 GNDVIAMRSATKTAVERARAGEGPTLIEADTYRHSGHSRSDP-AKYRPEEEVKS-WFARD 274
Query: 182 PITSFKEKVINNQLVTPDQLKEIDAKVRKETDEASKQAKADPE 310
PI + + D E++ + D A A PE
Sbjct: 275 PIVQLRNAI--EASGGADAAAEVERTAHTDVDAARDLALTWPE 315
>UniRef50_Q8AB00 Cluster: 2-oxoisovalerate dehydrogenase beta
subunit; n=11; cellular organisms|Rep: 2-oxoisovalerate
dehydrogenase beta subunit - Bacteroides
thetaiotaomicron
Length = 678
Score = 68.5 bits (160), Expect = 1e-10
Identities = 41/160 (25%), Positives = 79/160 (49%), Gaps = 2/160 (1%)
Frame = +2
Query: 2 GMDVIATREATKFAIDYCTSGKGPLLIEMETYRYSGHSMSDPGTSYRTRDEVQEVRQTRD 181
G DV + A A +Y S + P++++ R HS SD T YR +E++ V++ D
Sbjct: 217 GKDVFDSMNAMTEAREYAISTRNPVIVQANCVRIGSHSNSDKHTLYRDENELEYVKEA-D 275
Query: 182 PITSFKEKVINNQLVTPDQLKEIDAKVRKETDEASKQAKADPEIPIEELSGDIYYSNLEP 361
P+ F+ ++ + +T ++L +I+A+ +KE A+++A A PE + + + +P
Sbjct: 276 PLMKFRRMLLRYKRLTEEELLQIEAESKKELSAANRKALAAPEPDPKSIYDFVMPEPYQP 335
Query: 362 --FIRGTHPGAQLQHIQVAARK*TVSQFKKEKHKSILWGR 475
+ GTH + V A T+ + + +WG+
Sbjct: 336 QKYKEGTHQEEGEKTFLVNAINETLKAEFRHNPDTFIWGQ 375
>UniRef50_Q1ATM5 Cluster: Pyruvate dehydrogenase; n=1; Rubrobacter
xylanophilus DSM 9941|Rep: Pyruvate dehydrogenase -
Rubrobacter xylanophilus (strain DSM 9941 / NBRC 16129)
Length = 353
Score = 67.7 bits (158), Expect = 2e-10
Identities = 38/114 (33%), Positives = 60/114 (52%)
Frame = +2
Query: 2 GMDVIATREATKFAIDYCTSGKGPLLIEMETYRYSGHSMSDPGTSYRTRDEVQEVRQTRD 181
GMD+ A E + + P +E TYR + H +D YRT++EV++ R RD
Sbjct: 231 GMDLEAVIECGERVAERVRETGRPYAVEAITYRIAPHGAADFFEKYRTKEEVEKWR-ARD 289
Query: 182 PITSFKEKVINNQLVTPDQLKEIDAKVRKETDEASKQAKADPEIPIEELSGDIY 343
PI ++K++ + ++++EI + R+ EA K A E PIEEL D+Y
Sbjct: 290 PIGILEKKLLERDALDEERIEEIKDEARQRVSEAVKYADESEEPPIEELYTDVY 343
>UniRef50_Q1ARM0 Cluster: Pyruvate dehydrogenase; n=3; Bacteria|Rep:
Pyruvate dehydrogenase - Rubrobacter xylanophilus
(strain DSM 9941 / NBRC 16129)
Length = 332
Score = 67.3 bits (157), Expect = 3e-10
Identities = 37/118 (31%), Positives = 66/118 (55%), Gaps = 6/118 (5%)
Frame = +2
Query: 2 GMDVIATREATKFAIDYCTSGKGPLLIEMETYRYSGHSMSDPGTS--YRTRDEVQEVRQT 175
G DVI+ EA A+ +G+GP LIE TYR+ GH+ + S YR +E++E +
Sbjct: 205 GNDVISVHEAVSEAVGRARAGEGPSLIEARTYRWHGHNEGEEAFSGPYRPEEEIEEWK-G 263
Query: 176 RDPITSFKEKVINNQLVTPDQLKEIDAKVRKETDEASK----QAKADPEIPIEELSGD 337
+DPIT+F +++ + ++++ +DA+ ++ ++A + A DPE + L D
Sbjct: 264 KDPITTFAARLVEQGVFAREEIERVDAEEKERIEDAVRFAVESAYPDPEEALMHLFYD 321
>UniRef50_Q0RVK8 Cluster: Probable pyruvate dehydrogenase; n=1;
Rhodococcus sp. RHA1|Rep: Probable pyruvate
dehydrogenase - Rhodococcus sp. (strain RHA1)
Length = 344
Score = 67.3 bits (157), Expect = 3e-10
Identities = 39/114 (34%), Positives = 58/114 (50%)
Frame = +2
Query: 2 GMDVIATREATKFAIDYCTSGKGPLLIEMETYRYSGHSMSDPGTSYRTRDEVQEVRQTRD 181
G D A A + G GP L+E +TYR +GH DP SYR + EV E + RD
Sbjct: 228 GNDPGAVYTTLAAAFERARGGGGPTLVEAKTYRLNGHYEGDP-QSYRDKAEVAEWAE-RD 285
Query: 182 PITSFKEKVINNQLVTPDQLKEIDAKVRKETDEASKQAKADPEIPIEELSGDIY 343
P+T ++ +++ Q VT +QL + + E A +A P +++ GDIY
Sbjct: 286 PVTCYRARLLQQQNVTEEQLHTAEREAADEIRTAMTEALNAPPAGKDDIFGDIY 339
>UniRef50_A0LLM4 Cluster: Pyruvate dehydrogenase; n=1;
Syntrophobacter fumaroxidans MPOB|Rep: Pyruvate
dehydrogenase - Syntrophobacter fumaroxidans (strain DSM
10017 / MPOB)
Length = 365
Score = 66.9 bits (156), Expect = 3e-10
Identities = 42/124 (33%), Positives = 66/124 (53%), Gaps = 2/124 (1%)
Frame = +2
Query: 2 GMDVIATREATKFAIDYCTSGKGPLLIEMETYRYSGHSMSDPGTSYRTRDEVQE-VRQTR 178
G DV+A A K A+D +G GP IE TYR S H+ +D YR +EV++ VR R
Sbjct: 225 GNDVLAVYAAAKEAVDRARAGGGPSFIESVTYRLSMHTTADDPKKYRREEEVEQWVR--R 282
Query: 179 DPITSFKEKVINNQLVTPDQLKEIDAKVRKETDEASKQAKADPEIPIEELS-GDIYYSNL 355
DPI F++ ++ L++ + + I +V+ E EA ++ E P + + D Y L
Sbjct: 283 DPIIRFEKYLLGRGLLSEESVAGIADEVQAEIKEAEERWTRMTEKPADPMEMFDHAYEEL 342
Query: 356 EPFI 367
P++
Sbjct: 343 PPYL 346
>UniRef50_Q3E8Q6 Cluster: Uncharacterized protein At5g34780.1; n=1;
Arabidopsis thaliana|Rep: Uncharacterized protein
At5g34780.1 - Arabidopsis thaliana (Mouse-ear cress)
Length = 365
Score = 66.5 bits (155), Expect = 4e-10
Identities = 35/114 (30%), Positives = 60/114 (52%)
Frame = +2
Query: 2 GMDVIATREATKFAIDYCTSGKGPLLIEMETYRYSGHSMSDPGTSYRTRDEVQEVRQTRD 181
G D +A A A + + + P+LIEM YR HS SD T YR DE+Q + +R+
Sbjct: 98 GNDALAVYSAVCSAREMAVTEQRPVLIEMMIYRVGHHSTSDDSTKYRAADEIQYWKMSRN 157
Query: 182 PITSFKEKVINNQLVTPDQLKEIDAKVRKETDEASKQAKADPEIPIEELSGDIY 343
+ F++ V +N + + ++ + RK+ +A + A+ + P+ EL D+Y
Sbjct: 158 SVNRFRKSVEDNGWWSEEDESKLRSNARKQLLQAIQAAEKWEKQPLTELFNDVY 211
>UniRef50_Q4MTG0 Cluster: Pyruvate dehydrogenase E1 component
subunit alpha; n=38; Bacilli|Rep: Pyruvate dehydrogenase
E1 component subunit alpha - Bacillus cereus
Length = 371
Score = 66.5 bits (155), Expect = 4e-10
Identities = 47/119 (39%), Positives = 67/119 (56%), Gaps = 5/119 (4%)
Frame = +2
Query: 2 GMDVIATREATKFAIDYCTSGKGPLLIEMETYRYSGHSMS-DPGTSYRTRDEVQEVRQTR 178
GMD +A AT FA + +G+GP LIE T+RY H+M+ D T YRT+D E Q +
Sbjct: 238 GMDPLAVYAATAFARERAVNGEGPTLIETLTFRYGPHTMAGDDPTRYRTKDIENEWEQ-K 296
Query: 179 DPITSFKEKVINNQLVTPDQLKEIDAKVRKETDEASKQ--AKAD--PEIPIEELSGDIY 343
DPI F+ + N L + +E++ KV +E E KQ AKAD P+ + +L +Y
Sbjct: 297 DPIVRFRAFLENKGLWS----QEVEEKVIEEAKEDIKQAIAKADQAPKQKVTDLMEIMY 351
>UniRef50_Q9KG99 Cluster: Pyruvate dehydrogenase E1 (Lipoamide)
alpha subunit; n=1; Bacillus halodurans|Rep: Pyruvate
dehydrogenase E1 (Lipoamide) alpha subunit - Bacillus
halodurans
Length = 367
Score = 65.7 bits (153), Expect = 8e-10
Identities = 32/115 (27%), Positives = 60/115 (52%), Gaps = 1/115 (0%)
Frame = +2
Query: 2 GMDVIATREATKFAIDYCTSGKGPLLIEMETYRYSGHSMSDPGTSYRTRDEVQEV-RQTR 178
G D+ A K AI+ G+GP LIE T R+ H+ +D YR ++E++ ++ +
Sbjct: 230 GNDIFAVYLTVKRAIEQARKGRGPTLIEAVTTRFGSHTTADDAKKYRDQEEIERTWKEMQ 289
Query: 179 DPITSFKEKVINNQLVTPDQLKEIDAKVRKETDEASKQAKADPEIPIEELSGDIY 343
DP+T K + ++ ++ ++ AK+R+ DE A+ P+ I ++ +Y
Sbjct: 290 DPLTRLKAYIQAKGWLSEEEEAQMKAKIRETIDEELSMAEQYPKPSISQMFEHVY 344
>UniRef50_Q67ME6 Cluster: Branched-chain alpha-keto acid
dehydrogenase E1 alpha subunit; n=23; Bacteria|Rep:
Branched-chain alpha-keto acid dehydrogenase E1 alpha
subunit - Symbiobacterium thermophilum
Length = 352
Score = 64.5 bits (150), Expect = 2e-09
Identities = 38/114 (33%), Positives = 56/114 (49%)
Frame = +2
Query: 2 GMDVIATREATKFAIDYCTSGKGPLLIEMETYRYSGHSMSDPGTSYRTRDEVQEVRQTRD 181
G DV+A E K A + G+GP LIE R + HS D YR +E+ V Q RD
Sbjct: 237 GTDVLAVYEVVKEAHERARRGEGPTLIEARCIRITSHSSDDDQRRYRDPEEIAAV-QVRD 295
Query: 182 PITSFKEKVINNQLVTPDQLKEIDAKVRKETDEASKQAKADPEIPIEELSGDIY 343
PI ++ + + L+ +E++ KV D+A+ A+A P EE +Y
Sbjct: 296 PIRKARQYLFEHGLMDEAAEQELERKVAAIVDDATDWAEAQPYAAPEEALRHVY 349
>UniRef50_Q02C52 Cluster: Pyruvate dehydrogenase; n=1; Solibacter
usitatus Ellin6076|Rep: Pyruvate dehydrogenase -
Solibacter usitatus (strain Ellin6076)
Length = 340
Score = 64.5 bits (150), Expect = 2e-09
Identities = 36/114 (31%), Positives = 61/114 (53%)
Frame = +2
Query: 2 GMDVIATREATKFAIDYCTSGKGPLLIEMETYRYSGHSMSDPGTSYRTRDEVQEVRQTRD 181
G DV+A EAT+ A+ + G GP L+E +T+R +GHS D T Y + +E + D
Sbjct: 226 GNDVLAVYEATQRAVTHARGGLGPYLLECKTFRMTGHSAHDAAT-YVPKGLFEEWGKL-D 283
Query: 182 PITSFKEKVINNQLVTPDQLKEIDAKVRKETDEASKQAKADPEIPIEELSGDIY 343
PI +++++ + +++ E+ A V +E D+A A+ P L D+Y
Sbjct: 284 PIVRLEKRMLEERWSLQEEIDELHAAVIREVDDAVAWAEQSPYPDAASLLDDVY 337
>UniRef50_Q3DZ88 Cluster: Dehydrogenase, E1 component; n=1;
Chloroflexus aurantiacus J-10-fl|Rep: Dehydrogenase, E1
component - Chloroflexus aurantiacus J-10-fl
Length = 334
Score = 63.7 bits (148), Expect = 3e-09
Identities = 40/103 (38%), Positives = 58/103 (56%)
Frame = +2
Query: 2 GMDVIATREATKFAIDYCTSGKGPLLIEMETYRYSGHSMSDPGTSYRTRDEVQEVRQTRD 181
G D +A EA + A+ SG GP L+E TYR+ GHS SD +YR+RDEV++ Q+RD
Sbjct: 226 GNDALAVYEAVRQAVARARSGYGPTLVEAITYRWKGHSKSD-RQAYRSRDEVKD-WQSRD 283
Query: 182 PITSFKEKVINNQLVTPDQLKEIDAKVRKETDEASKQAKADPE 310
PI + ++ + K I + R +EA + A+A PE
Sbjct: 284 PIMRLARLI----QMSDAEFKAIVDQARTMIEEAVEFAQASPE 322
>UniRef50_Q97YF6 Cluster: Pyruvate dehydrogenase, alpha subunit
(Lipoamide); n=2; Sulfolobaceae|Rep: Pyruvate
dehydrogenase, alpha subunit (Lipoamide) - Sulfolobus
solfataricus
Length = 345
Score = 63.7 bits (148), Expect = 3e-09
Identities = 37/94 (39%), Positives = 49/94 (52%)
Frame = +2
Query: 2 GMDVIATREATKFAIDYCTSGKGPLLIEMETYRYSGHSMSDPGTSYRTRDEVQEVRQTRD 181
GMDVI +K AI+ G GP LIE TYRY GH D G YRT++EV E + D
Sbjct: 233 GMDVIDVYSTSKKAIERARKGFGPTLIEALTYRYVGHFEGD-GEEYRTKEEV-EFWSSLD 290
Query: 182 PITSFKEKVINNQLVTPDQLKEIDAKVRKETDEA 283
PI + +++ D L + + RK+ EA
Sbjct: 291 PIRRLENRLLRLNYADSDILARLREEARKQVQEA 324
>UniRef50_P37940 Cluster: 2-oxoisovalerate dehydrogenase subunit
alpha; n=37; Firmicutes|Rep: 2-oxoisovalerate
dehydrogenase subunit alpha - Bacillus subtilis
Length = 330
Score = 63.7 bits (148), Expect = 3e-09
Identities = 39/111 (35%), Positives = 60/111 (54%), Gaps = 4/111 (3%)
Frame = +2
Query: 2 GMDVIATREATKFAIDYCTSGKGPLLIEMETYRYSGHSMSDPGTSYRTRDEVQEVRQTRD 181
G D + +A K A + G+GP LIE +YR + HS D +SYR R+EV+E +++ D
Sbjct: 216 GNDPLEVYQAVKEARERARRGEGPTLIETISYRLTPHSSDDDDSSYRGREEVEEAKKS-D 274
Query: 182 PITSF----KEKVINNQLVTPDQLKEIDAKVRKETDEASKQAKADPEIPIE 322
P+ ++ KE + + + L EI A V + TDEA A PE ++
Sbjct: 275 PLLTYQAYLKETGLLSDEIEQTMLDEIMAIVNEATDEAENAPYAAPESALD 325
>UniRef50_Q835M4 Cluster: Pyruvate dehydrogenase complex E1
component, alpha subunit; n=10; Bacilli|Rep: Pyruvate
dehydrogenase complex E1 component, alpha subunit -
Enterococcus faecalis (Streptococcus faecalis)
Length = 371
Score = 63.3 bits (147), Expect = 4e-09
Identities = 37/115 (32%), Positives = 64/115 (55%), Gaps = 1/115 (0%)
Frame = +2
Query: 2 GMDVIATREATKFAIDYCTSGKGPLLIEMETYRYSGHSMS-DPGTSYRTRDEVQEVRQTR 178
GMD +A K A D+ +G GP+LIE TYRY H++S D T YR+++ E Q +
Sbjct: 238 GMDPLAVYAIAKEARDWSAAGNGPVLIETLTYRYGPHTLSGDDPTRYRSKEMDDEWVQ-K 296
Query: 179 DPITSFKEKVINNQLVTPDQLKEIDAKVRKETDEASKQAKADPEIPIEELSGDIY 343
DP+T F++ + + L + + +EI K ++E A +A P+ + + +++
Sbjct: 297 DPLTRFRKYLTDKGLWSEAKEEEIIEKTKEEIKVAIAEADKAPKQKVSDFLKNMF 351
>UniRef50_Q9RPS5 Cluster: TPP-dependent branched-chain alpha-keto
acid dehydrogenase, E1 alpha subunit; n=3;
Lactobacillales|Rep: TPP-dependent branched-chain
alpha-keto acid dehydrogenase, E1 alpha subunit -
Enterococcus faecalis (Streptococcus faecalis)
Length = 330
Score = 63.3 bits (147), Expect = 4e-09
Identities = 31/114 (27%), Positives = 64/114 (56%)
Frame = +2
Query: 2 GMDVIATREATKFAIDYCTSGKGPLLIEMETYRYSGHSMSDPGTSYRTRDEVQEVRQTRD 181
G D A K A+ KGP LIE+ R + HS D + YR+++E++E+++ D
Sbjct: 216 GSDFAEVYLAFKEAVKAARGKKGPKLIELMVSRLTSHSADDDQSVYRSKEEIEEMKK-ND 274
Query: 182 PITSFKEKVINNQLVTPDQLKEIDAKVRKETDEASKQAKADPEIPIEELSGDIY 343
+ F+++++ +T + + +ID ++R E ++A+ +A+A P+ + ++Y
Sbjct: 275 AVKLFEKQLLEEGYLTDEDIAKIDEEIRAEINQATDEAEAMPDPVPTSILEEVY 328
>UniRef50_P27745 Cluster: Acetoin:2,6-dichlorophenolindophenol
oxidoreductase subunit alpha; n=58; cellular
organisms|Rep: Acetoin:2,6-dichlorophenolindophenol
oxidoreductase subunit alpha - Ralstonia eutropha
(strain ATCC 17699 / H16 / DSM 428 / Stanier
337)(Cupriavidus necator (strain ATCC 17699 / H16 / DSM
428 / Stanier337))
Length = 333
Score = 63.3 bits (147), Expect = 4e-09
Identities = 38/116 (32%), Positives = 56/116 (48%)
Frame = +2
Query: 2 GMDVIATREATKFAIDYCTSGKGPLLIEMETYRYSGHSMSDPGTSYRTRDEVQEVRQTRD 181
G D A EA I G GP L+E + R+ GH D T YR E+ ++R +D
Sbjct: 218 GTDFFAVHEAAGEVIRRAREGGGPSLLECKMVRFYGHFEGDAQT-YRAAGELDDIRANKD 276
Query: 182 PITSFKEKVINNQLVTPDQLKEIDAKVRKETDEASKQAKADPEIPIEELSGDIYYS 349
+ F V +V ++L ID +V + A ++AKA P+ E+L D+Y S
Sbjct: 277 CLKLFGRAVTQAGVVAREELDTIDREVAALIEHAVQEAKAAPQPGPEDLLTDVYVS 332
>UniRef50_A5V4J0 Cluster: Pyruvate dehydrogenase; n=2; Sphingomonas
wittichii RW1|Rep: Pyruvate dehydrogenase - Sphingomonas
wittichii RW1
Length = 327
Score = 62.9 bits (146), Expect = 6e-09
Identities = 33/104 (31%), Positives = 56/104 (53%)
Frame = +2
Query: 29 ATKFAIDYCTSGKGPLLIEMETYRYSGHSMSDPGTSYRTRDEVQEVRQTRDPITSFKEKV 208
A ++AID +G+GP IE T+R++GH + + G Y + E+ QTRDP+ + ++
Sbjct: 220 AARWAIDRARAGEGPTFIEATTFRFNGHLIGEAG-GYMDK-ELYAASQTRDPMPILRRRL 277
Query: 209 INNQLVTPDQLKEIDAKVRKETDEASKQAKADPEIPIEELSGDI 340
++ + +L +DA +R E D A + A A EL D+
Sbjct: 278 VDQGIAAAGELDALDASIRAEIDAAVQAAYAADYPDPSELKVDV 321
>UniRef50_Q020J5 Cluster: Dehydrogenase, E1 component; n=1;
Solibacter usitatus Ellin6076|Rep: Dehydrogenase, E1
component - Solibacter usitatus (strain Ellin6076)
Length = 697
Score = 61.3 bits (142), Expect = 2e-08
Identities = 39/133 (29%), Positives = 64/133 (48%), Gaps = 1/133 (0%)
Frame = +2
Query: 2 GMDVIATREATKFAIDYCTSGKGPLLIEMETYRYSGHSMSDPGTSYRTRDEVQEVRQTRD 181
G D A+ +A + A+ YC G GP L+ R HS+SD Y+T E + RD
Sbjct: 225 GTDFFASWQAMQAAVRYCREGSGPALVHAHCIRPYSHSLSDDERLYKTPAE-RAAEAERD 283
Query: 182 PITSFKEKVINNQLVTPDQLKEIDAKVRKETDEASKQAKAD-PEIPIEELSGDIYYSNLE 358
P+ F + +I+ ++ L++I ++ +E +A++ A D P P L YS+L+
Sbjct: 284 PVLRFPKLLIDEGVLDRRMLQDITHEIDEEIQQATQTALHDEPPSPASALVH--LYSDLD 341
Query: 359 PFIRGTHPGAQLQ 397
P H + Q
Sbjct: 342 PCAPAFHAEPRFQ 354
>UniRef50_Q6MAE2 Cluster: Putative pyruvate dehydrogenase
(Lipoamide), E1 component, alpha chain; n=1; Candidatus
Protochlamydia amoebophila UWE25|Rep: Putative pyruvate
dehydrogenase (Lipoamide), E1 component, alpha chain -
Protochlamydia amoebophila (strain UWE25)
Length = 342
Score = 60.9 bits (141), Expect = 2e-08
Identities = 30/94 (31%), Positives = 57/94 (60%)
Frame = +2
Query: 71 PLLIEMETYRYSGHSMSDPGTSYRTRDEVQEVRQTRDPITSFKEKVINNQLVTPDQLKEI 250
P+L+E+ T R+ GHS+SDPG YR +D ++++ +DPI + + +I ++T D +K++
Sbjct: 248 PVLVEVVTERFKGHSISDPGL-YRAKDTLKQI-MAKDPILALQAVLIKKGILTEDMVKQM 305
Query: 251 DAKVRKETDEASKQAKADPEIPIEELSGDIYYSN 352
+ + R++ EA A+ P + L D++ N
Sbjct: 306 NKENREKIIEAMSFAENSPWPDPQTLEEDVFAPN 339
>UniRef50_Q8CX87 Cluster: Pyruvate dehydrogenase E1 (Lipoamide)
alpha subunit; n=5; Bacillaceae|Rep: Pyruvate
dehydrogenase E1 (Lipoamide) alpha subunit -
Oceanobacillus iheyensis
Length = 358
Score = 60.5 bits (140), Expect = 3e-08
Identities = 32/109 (29%), Positives = 55/109 (50%)
Frame = +2
Query: 2 GMDVIATREATKFAIDYCTSGKGPLLIEMETYRYSGHSMSDPGTSYRTRDEVQEVRQTRD 181
G D+ A TK A++ +G+GP LIE T+RY H+ +D T YR + E E + D
Sbjct: 223 GNDIFAAYFETKKALERARNGEGPSLIEAVTWRYGAHTTADDPTKYRNQKEENEKHRQND 282
Query: 182 PITSFKEKVINNQLVTPDQLKEIDAKVRKETDEASKQAKADPEIPIEEL 328
PIT + + ++++ +V++E D A K + P + ++
Sbjct: 283 PITRLELFMKAYGFWDEAVVEQLKEEVKEEIDGAVKDLETMPPADVNDI 331
>UniRef50_Q67SE7 Cluster: Pyruvate dehydrogenase E1 alpha subunit;
n=2; Bacilli|Rep: Pyruvate dehydrogenase E1 alpha
subunit - Symbiobacterium thermophilum
Length = 368
Score = 60.5 bits (140), Expect = 3e-08
Identities = 34/114 (29%), Positives = 59/114 (51%)
Frame = +2
Query: 2 GMDVIATREATKFAIDYCTSGKGPLLIEMETYRYSGHSMSDPGTSYRTRDEVQEVRQTRD 181
G DV+A AI+ SG GP L+E T+RY H+ SD YR+++E++E Q RD
Sbjct: 229 GQDVLAVLAVMHEAIERARSGGGPTLVESVTFRYGPHTTSDDPKRYRSQEELEE-WQARD 287
Query: 182 PITSFKEKVINNQLVTPDQLKEIDAKVRKETDEASKQAKADPEIPIEELSGDIY 343
PI + +++ + + + R++ A +A+A P +++L +Y
Sbjct: 288 PIERLRLYLVSQGQWSDSDDEALWTAAREQVAAAVAEAEAMPRPSVDDLFDYLY 341
>UniRef50_Q6YPX5 Cluster: Thiamine pyrophosphate-dependent
dehydrogenase, E1 component alpha subunit; n=2;
Candidatus Phytoplasma asteris|Rep: Thiamine
pyrophosphate-dependent dehydrogenase, E1 component
alpha subunit - Onion yellows phytoplasma
Length = 363
Score = 60.1 bits (139), Expect = 4e-08
Identities = 29/90 (32%), Positives = 53/90 (58%)
Frame = +2
Query: 2 GMDVIATREATKFAIDYCTSGKGPLLIEMETYRYSGHSMSDPGTSYRTRDEVQEVRQTRD 181
G D++A A + A + G GP LIE +YR HS +D + YR+++E E R+ +D
Sbjct: 226 GNDILAVYVAAQEAFNEARKGNGPTLIENVSYRLEAHSTNDNASVYRSKEEELEWRK-KD 284
Query: 182 PITSFKEKVINNQLVTPDQLKEIDAKVRKE 271
PI F++ ++N +T Q+++ + + ++E
Sbjct: 285 PIVRFQKYLMNKGYLTQKQVEQFEKEAQEE 314
>UniRef50_Q97CK0 Cluster: 2-oxoisovalerate dehydrogenase alpha
subunit; n=2; Thermoplasma|Rep: 2-oxoisovalerate
dehydrogenase alpha subunit - Thermoplasma volcanium
Length = 337
Score = 60.1 bits (139), Expect = 4e-08
Identities = 37/114 (32%), Positives = 59/114 (51%)
Frame = +2
Query: 2 GMDVIATREATKFAIDYCTSGKGPLLIEMETYRYSGHSMSDPGTSYRTRDEVQEVRQTRD 181
G D I T A K A++Y SG P+L+E +YR HS SD + YR ++EV+E D
Sbjct: 210 GNDFIKTYNAVKEAVEYARSGN-PILVEARSYRMGPHSTSDDPSKYR-QNEVKE-GDEND 266
Query: 182 PITSFKEKVINNQLVTPDQLKEIDAKVRKETDEASKQAKADPEIPIEELSGDIY 343
P+ ++ VI+ +++ ++ I + RK DE ++ P L D+Y
Sbjct: 267 PLVIAEKAVISKGILSQSEVNRIKDESRKMIDEKFEERLKIPAPDPSTLFDDVY 320
>UniRef50_P35485 Cluster: Pyruvate dehydrogenase E1 component
subunit alpha; n=2; Firmicutes|Rep: Pyruvate
dehydrogenase E1 component subunit alpha - Acholeplasma
laidlawii
Length = 345
Score = 60.1 bits (139), Expect = 4e-08
Identities = 35/101 (34%), Positives = 58/101 (57%), Gaps = 1/101 (0%)
Frame = +2
Query: 2 GMDVIATREATKFAIDYCTSGKGPLLIEMETYRYSGHSMS-DPGTSYRTRDEVQEVRQTR 178
G D++A A+K A+D G GP LIE TYR H+ S DP + YRT++E E + +
Sbjct: 209 GNDMLAMYVASKEAMDRARKGDGPTLIEAFTYRMGPHTTSDDPCSIYRTKEEENEWAK-K 267
Query: 179 DPITSFKEKVINNQLVTPDQLKEIDAKVRKETDEASKQAKA 301
D I FK +IN + ++ K+++ +V E ++ K+ ++
Sbjct: 268 DQIARFKTYLINKGYWSEEEDKKLEEEVLAEINDTFKKVES 308
>UniRef50_Q2J998 Cluster: Pyruvate dehydrogenase; n=1; Frankia sp.
CcI3|Rep: Pyruvate dehydrogenase - Frankia sp. (strain
CcI3)
Length = 417
Score = 59.7 bits (138), Expect = 5e-08
Identities = 29/62 (46%), Positives = 38/62 (61%)
Frame = +2
Query: 2 GMDVIATREATKFAIDYCTSGKGPLLIEMETYRYSGHSMSDPGTSYRTRDEVQEVRQTRD 181
G DV+A T +A+D SG+GP+LIE TYR + H+ SD T Y+ DE+ Q RD
Sbjct: 285 GNDVLAVHAVTTWALDRARSGRGPVLIEANTYRMAPHTTSDDATRYQPPDEI-TAWQARD 343
Query: 182 PI 187
PI
Sbjct: 344 PI 345
>UniRef50_A4XHV5 Cluster: Transketolase, central region; n=3;
Bacteria|Rep: Transketolase, central region -
Caldicellulosiruptor saccharolyticus (strain ATCC 43494
/ DSM 8903)
Length = 823
Score = 59.7 bits (138), Expect = 5e-08
Identities = 31/89 (34%), Positives = 55/89 (61%)
Frame = +2
Query: 2 GMDVIATREATKFAIDYCTSGKGPLLIEMETYRYSGHSMSDPGTSYRTRDEVQEVRQTRD 181
G + +A +A K +GP+L+++ TYR +GHS SD T YRT++E+ E ++D
Sbjct: 310 GYNPLAVIDAMKRKKYLLEQKQGPVLLDVVTYRLTGHSPSDSST-YRTKEEL-EAWASQD 367
Query: 182 PITSFKEKVINNQLVTPDQLKEIDAKVRK 268
P+ +FK+++I + T D++ EI V++
Sbjct: 368 PLVTFKDELIRVGVATEDKINEIQQNVKE 396
>UniRef50_Q49108 Cluster: Pyruvate dehydrogenase EI alpha subunit;
n=5; Mollicutes|Rep: Pyruvate dehydrogenase EI alpha
subunit - Mycoplasma capricolum
Length = 370
Score = 58.8 bits (136), Expect = 9e-08
Identities = 28/89 (31%), Positives = 51/89 (57%)
Frame = +2
Query: 2 GMDVIATREATKFAIDYCTSGKGPLLIEMETYRYSGHSMSDPGTSYRTRDEVQEVRQTRD 181
G D +A K ++Y G GP+L+E +TYR HS SD +YR + E +E+ + D
Sbjct: 228 GNDYLACIGVFKEVVEYVRKGNGPVLVECDTYRLGAHSSSDNPDAYRPKGEFEEMAKF-D 286
Query: 182 PITSFKEKVINNQLVTPDQLKEIDAKVRK 268
P+ K+ +I+ ++ + +Q +++A+ K
Sbjct: 287 PLIRLKQYLIDKKIWSDEQQAQLEAEQDK 315
>UniRef50_A7K3C9 Cluster: Dehydrogenase E1 component superfamily;
n=10; Gammaproteobacteria|Rep: Dehydrogenase E1
component superfamily - Vibrio sp. Ex25
Length = 398
Score = 58.8 bits (136), Expect = 9e-08
Identities = 31/79 (39%), Positives = 44/79 (55%)
Frame = +2
Query: 2 GMDVIATREATKFAIDYCTSGKGPLLIEMETYRYSGHSMSDPGTSYRTRDEVQEVRQTRD 181
G DV+A +ATK A++ GKG LIE +YR S H+ +D T YR D+VQ Q +
Sbjct: 259 GNDVVAVYDATKTALERARKGKGATLIEAVSYRLSDHTTADDATRYRKEDDVQTAWQ-YE 317
Query: 182 PITSFKEKVINNQLVTPDQ 238
PI K ++N + +Q
Sbjct: 318 PIARLKTYLLNQGAWSDEQ 336
>UniRef50_Q749T8 Cluster: Pyruvate dehydrogenase complex E1
component, alpha subunit; n=4; Geobacter|Rep: Pyruvate
dehydrogenase complex E1 component, alpha subunit -
Geobacter sulfurreducens
Length = 352
Score = 58.4 bits (135), Expect = 1e-07
Identities = 35/102 (34%), Positives = 51/102 (50%)
Frame = +2
Query: 2 GMDVIATREATKFAIDYCTSGKGPLLIEMETYRYSGHSMSDPGTSYRTRDEVQEVRQTRD 181
G DV+A AT A+ G GP IE TYR + H+ +D + YR +V+ R RD
Sbjct: 225 GNDVLAVFRATGEALVRARDGGGPTFIECLTYRMADHTTADDASRYRPPADVEAWRD-RD 283
Query: 182 PITSFKEKVINNQLVTPDQLKEIDAKVRKETDEASKQAKADP 307
P+ F+ + L D E+ AK E DEA ++ ++ P
Sbjct: 284 PLLRFERFLAKRGLWNGDYGAEVQAKAEGEIDEAVRRYESVP 325
>UniRef50_Q3WCG3 Cluster: Pyruvate dehydrogenase; n=4;
Actinomycetales|Rep: Pyruvate dehydrogenase - Frankia
sp. EAN1pec
Length = 332
Score = 58.4 bits (135), Expect = 1e-07
Identities = 33/114 (28%), Positives = 54/114 (47%)
Frame = +2
Query: 2 GMDVIATREATKFAIDYCTSGKGPLLIEMETYRYSGHSMSDPGTSYRTRDEVQEVRQTRD 181
G D +A A++ SG GP L+E T+R+ GH DP +Y + + + D
Sbjct: 213 GNDPLAVLAVLTQAVERARSGGGPTLVECVTFRFRGHYFGDP-MAYIPAERMAAAVEA-D 270
Query: 182 PITSFKEKVINNQLVTPDQLKEIDAKVRKETDEASKQAKADPEIPIEELSGDIY 343
PI F+ +++ + +L EI+A +EA A P ++EL D+Y
Sbjct: 271 PIPRFRSRLLETGVCDEHELDEIEAAAVAAVEEALTAVLAAPVAALDELDRDVY 324
>UniRef50_Q4A1S8 Cluster: Putative uncharacterized protein; n=4;
Caenorhabditis|Rep: Putative uncharacterized protein -
Caenorhabditis elegans
Length = 432
Score = 58.4 bits (135), Expect = 1e-07
Identities = 39/104 (37%), Positives = 53/104 (50%), Gaps = 4/104 (3%)
Frame = +2
Query: 2 GMDVIATREATKFAIDYCTSGKGPLLIEMETYRYSGHSMSDPGTSYRTRDEVQEVRQTRD 181
G D++A ATK A + + P+LIE TYR HS SD T+YR+ DEVQ
Sbjct: 285 GNDLLAVYNATKEARRVALTNR-PVLIEAMTYRLGHHSTSDDSTAYRSSDEVQTWGDKDH 343
Query: 182 PITSFKEKVIN----NQLVTPDQLKEIDAKVRKETDEASKQAKA 301
PIT FK+ + N+ + KE+ +V E A K+ KA
Sbjct: 344 PITRFKKYITERGWWNEEKEMEWQKEVKKRVLTEFAAAEKRKKA 387
>UniRef50_P21873 Cluster: Pyruvate dehydrogenase E1 component
subunit alpha; n=33; Bacilli|Rep: Pyruvate dehydrogenase
E1 component subunit alpha - Bacillus stearothermophilus
(Geobacillus stearothermophilus)
Length = 369
Score = 58.4 bits (135), Expect = 1e-07
Identities = 34/110 (30%), Positives = 60/110 (54%), Gaps = 1/110 (0%)
Frame = +2
Query: 2 GMDVIATREATKFAIDYCTSGKGPLLIEMETYRYSGHSMS-DPGTSYRTRDEVQEVRQTR 178
GMD +A A K A + +G+GP LIE +RY H+MS D T YR++ E++ +
Sbjct: 236 GMDPLAVYAAVKAARERAINGEGPTLIETLCFRYGPHTMSGDDPTRYRSK-ELENEWAKK 294
Query: 179 DPITSFKEKVINNQLVTPDQLKEIDAKVRKETDEASKQAKADPEIPIEEL 328
DP+ F++ + L + ++ + + ++E EA K+A P+ + +L
Sbjct: 295 DPLVRFRKFLEAKGLWSEEEENNVIEQAKEEIKEAIKKADETPKQKVTDL 344
>UniRef50_A6W004 Cluster: Transketolase domain protein; n=6;
Proteobacteria|Rep: Transketolase domain protein -
Marinomonas sp. MWYL1
Length = 701
Score = 58.0 bits (134), Expect = 2e-07
Identities = 32/107 (29%), Positives = 56/107 (52%), Gaps = 4/107 (3%)
Frame = +2
Query: 2 GMDVIATREATKFAIDYCTSGKGPLLIEMETYRYSGHSMSDPGTSYRTRDEVQEVRQTRD 181
G D T K A++Y SGKG L+ ++ R GH+ D T Y+ D + + Q RD
Sbjct: 237 GTDPELTPVLIKEAVEYVRSGKGTCLLRLKVPRLCGHTFQDTQT-YKNEDFIAD-EQARD 294
Query: 182 PITSFKEKVINNQLVTPDQLKEIDAK----VRKETDEASKQAKADPE 310
P+ K +++N +T D+ +++ + +R D+A ++ + DPE
Sbjct: 295 PLPKLKRYLLDNGFMTADEWHDLEDECYRDIRLSVDKAKERQQPDPE 341
>UniRef50_Q9RYC1 Cluster: 2-oxo acid dehydrogenase, E1 component,
alpha subunit; n=2; Deinococcus|Rep: 2-oxo acid
dehydrogenase, E1 component, alpha subunit - Deinococcus
radiodurans
Length = 381
Score = 57.6 bits (133), Expect = 2e-07
Identities = 35/103 (33%), Positives = 56/103 (54%), Gaps = 3/103 (2%)
Frame = +2
Query: 2 GMDVIATREATKFAIDYCTSGKGPLLIEMETYRYSGHSMSDPGT--SYRTRDEVQEVRQT 175
G DV+A E A ++ +G GP L+E TYR HS +D SYRTRDEV E
Sbjct: 244 GNDVVAVMEVCHHAAEWVRAGNGPALVECLTYRVGSHSNADADAEKSYRTRDEVNE-WLG 302
Query: 176 RDPITSFKEKVIN-NQLVTPDQLKEIDAKVRKETDEASKQAKA 301
RDPI + + + ++ ++ + A++ K+ D+ ++A+A
Sbjct: 303 RDPIQRVENLLEHLGDPISAEERAGMIAEIHKQIDDDVRRAEA 345
>UniRef50_A3CMZ3 Cluster: Pyruvate dehydrogenase, TPP-dependent E1
component alpha-subunit, putative; n=22; Bacteria|Rep:
Pyruvate dehydrogenase, TPP-dependent E1 component
alpha-subunit, putative - Streptococcus sanguinis
(strain SK36)
Length = 357
Score = 57.6 bits (133), Expect = 2e-07
Identities = 35/114 (30%), Positives = 57/114 (50%)
Frame = +2
Query: 2 GMDVIATREATKFAIDYCTSGKGPLLIEMETYRYSGHSMSDPGTSYRTRDEVQEVRQTRD 181
G D+ A + K A++ G+GP LIE TYR GH D Y+ + ++ D
Sbjct: 243 GKDLFAVYQVAKEAVERARRGEGPTLIEAVTYRDHGHFEGDE-QKYKALEGEEKDWADVD 301
Query: 182 PITSFKEKVINNQLVTPDQLKEIDAKVRKETDEASKQAKADPEIPIEELSGDIY 343
+ F++ I + L+T ++L I + RK+ +EA K A+ P E L D++
Sbjct: 302 ALDVFRDYAIEHGLLTEEELDAILEESRKDVEEAIKFAQDSPIPRSESLLEDVF 355
>UniRef50_Q5KUY4 Cluster: Pyruvate dehydrogenase E1 (Lipoamide)
alpha subunit; n=2; Geobacillus|Rep: Pyruvate
dehydrogenase E1 (Lipoamide) alpha subunit - Geobacillus
kaustophilus
Length = 359
Score = 57.2 bits (132), Expect = 3e-07
Identities = 37/114 (32%), Positives = 55/114 (48%)
Frame = +2
Query: 2 GMDVIATREATKFAIDYCTSGKGPLLIEMETYRYSGHSMSDPGTSYRTRDEVQEVRQTRD 181
G DV+A E K A++ G+GP+LIE TYR H+ +D T YR +EV E + +D
Sbjct: 223 GNDVLAVYETMKQAVEAARRGEGPMLIEALTYRLGPHTTADDPTKYRRPEEV-ETWRAKD 281
Query: 182 PITSFKEKVINNQLVTPDQLKEIDAKVRKETDEASKQAKADPEIPIEELSGDIY 343
P+ + + L T Q + A+V E A + A A I + +Y
Sbjct: 282 PLRRLRLLLERRGLWTEAQEDALVAQVNDEVTAAYEAAIASKSGSIVDAFDCVY 335
>UniRef50_Q3DYK5 Cluster: Dehydrogenase, E1 component; n=3;
Bacteria|Rep: Dehydrogenase, E1 component - Chloroflexus
aurantiacus J-10-fl
Length = 321
Score = 57.2 bits (132), Expect = 3e-07
Identities = 36/114 (31%), Positives = 58/114 (50%)
Frame = +2
Query: 2 GMDVIATREATKFAIDYCTSGKGPLLIEMETYRYSGHSMSDPGTSYRTRDEVQEVRQTRD 181
G D A ATK A++ +G GP IE +T R GH++ D +Y ++ + E + RD
Sbjct: 209 GNDFAAVYRATKEAVERARAGGGPTFIECKTMRMRGHAIHD-NMAYVPKELLAE-WEARD 266
Query: 182 PITSFKEKVINNQLVTPDQLKEIDAKVRKETDEASKQAKADPEIPIEELSGDIY 343
PI +E + + L+ +L + A++ E DEA A+A P L+ +Y
Sbjct: 267 PIARIEEVLRSRGLLDDAKLAALLARIEAELDEAQAFAEASPYPDPATLTDGVY 320
>UniRef50_P12694 Cluster: 2-oxoisovalerate dehydrogenase subunit
alpha, mitochondrial precursor; n=29; Euteleostomi|Rep:
2-oxoisovalerate dehydrogenase subunit alpha,
mitochondrial precursor - Homo sapiens (Human)
Length = 445
Score = 57.2 bits (132), Expect = 3e-07
Identities = 37/114 (32%), Positives = 55/114 (48%)
Frame = +2
Query: 2 GMDVIATREATKFAIDYCTSGKGPLLIEMETYRYSGHSMSDPGTSYRTRDEVQEVRQTRD 181
G DV A ATK A + P LIE TYR HS SD ++YR+ DEV +
Sbjct: 300 GNDVFAVYNATKEARRRAVAENQPFLIEAMTYRIGHHSTSDDSSAYRSVDEVNYWDKQDH 359
Query: 182 PITSFKEKVINNQLVTPDQLKEIDAKVRKETDEASKQAKADPEIPIEELSGDIY 343
PI+ + +++ +Q K + R++ EA +QA+ P+ L D+Y
Sbjct: 360 PISRLRHYLLSQGWWDEEQEKAWRKQSRRKVMEAFEQAERKPKPNPNLLFSDVY 413
>UniRef50_A6CP23 Cluster: Pyruvate dehydrogenase E1 (Lipoamide)
alpha subunit; n=2; Bacillus sp. SG-1|Rep: Pyruvate
dehydrogenase E1 (Lipoamide) alpha subunit - Bacillus
sp. SG-1
Length = 364
Score = 56.8 bits (131), Expect = 4e-07
Identities = 30/103 (29%), Positives = 50/103 (48%)
Frame = +2
Query: 2 GMDVIATREATKFAIDYCTSGKGPLLIEMETYRYSGHSMSDPGTSYRTRDEVQEVRQTRD 181
G D+ A T A++ +G+GP LIE T+RY H+ +D T YR + E E R+ D
Sbjct: 229 GNDIFAVYFETLKALERARNGEGPTLIEAVTWRYGAHTTADDPTKYRDQSESDERRKLGD 288
Query: 182 PITSFKEKVINNQLVTPDQLKEIDAKVRKETDEASKQAKADPE 310
PI + + + + + E D+A ++ ++ PE
Sbjct: 289 PIARLQRYMERQGWWDQEWADSVQKEYTAEMDQAVEELESYPE 331
>UniRef50_A6GG24 Cluster: Pyruvate dehydrogenase (Lipoamide), alpha
subunit; n=1; Plesiocystis pacifica SIR-1|Rep: Pyruvate
dehydrogenase (Lipoamide), alpha subunit - Plesiocystis
pacifica SIR-1
Length = 339
Score = 56.4 bits (130), Expect = 5e-07
Identities = 35/101 (34%), Positives = 51/101 (50%)
Frame = +2
Query: 8 DVIATREATKFAIDYCTSGKGPLLIEMETYRYSGHSMSDPGTSYRTRDEVQEVRQTRDPI 187
D RE A+ P LIE+ TYR+ GHSMSDP YR + E++ R +RD I
Sbjct: 223 DPFQVRERIGAAMKRAREESQPTLIEILTYRFRGHSMSDP-AKYRAKGELEAFR-SRDAI 280
Query: 188 TSFKEKVINNQLVTPDQLKEIDAKVRKETDEASKQAKADPE 310
+ ++ ++ D+L ID +V +E D A A P+
Sbjct: 281 ELSRRVLMEQHGMSEDELDAIDDEVIEEMDAAYTFADESPQ 321
>UniRef50_Q6A611 Cluster: Pyruvate dehydrogenase E1 component, alpha
subunit; n=1; Propionibacterium acnes|Rep: Pyruvate
dehydrogenase E1 component, alpha subunit -
Propionibacterium acnes
Length = 381
Score = 56.0 bits (129), Expect = 6e-07
Identities = 28/75 (37%), Positives = 41/75 (54%)
Frame = +2
Query: 2 GMDVIATREATKFAIDYCTSGKGPLLIEMETYRYSGHSMSDPGTSYRTRDEVQEVRQTRD 181
G DVIA + A++Y SGKGP+ +E TYR H+ +D T YRT +E +T D
Sbjct: 248 GNDVIAMMAVLRSALEYARSGKGPVFVEAWTYRMGAHTTTDDPTRYRTAEEESTWGKT-D 306
Query: 182 PITSFKEKVINNQLV 226
PI + + N ++
Sbjct: 307 PIVRLRTYLQNRGII 321
>UniRef50_Q2JA37 Cluster: Pyruvate dehydrogenase; n=11;
Actinomycetales|Rep: Pyruvate dehydrogenase - Frankia
sp. (strain CcI3)
Length = 388
Score = 56.0 bits (129), Expect = 6e-07
Identities = 26/69 (37%), Positives = 40/69 (57%)
Frame = +2
Query: 2 GMDVIATREATKFAIDYCTSGKGPLLIEMETYRYSGHSMSDPGTSYRTRDEVQEVRQTRD 181
G D A + A+++ SG+GP+L+E TYR H+ +D T YRT +EV Q RD
Sbjct: 247 GNDAPAVHGVLRAAVEHARSGRGPVLVEAVTYRLEAHTNADDATRYRTSEEV-AAWQARD 305
Query: 182 PITSFKEKV 208
P+T + ++
Sbjct: 306 PLTLLERQL 314
>UniRef50_Q53610 Cluster: Branched-chain alpha-keto acid
dehydrogenase E1-alpha subunit; n=16;
Actinomycetales|Rep: Branched-chain alpha-keto acid
dehydrogenase E1-alpha subunit - Streptomyces
avermitilis
Length = 406
Score = 55.6 bits (128), Expect = 8e-07
Identities = 27/62 (43%), Positives = 37/62 (59%)
Frame = +2
Query: 2 GMDVIATREATKFAIDYCTSGKGPLLIEMETYRYSGHSMSDPGTSYRTRDEVQEVRQTRD 181
G DV+A TK+A++ G+GP L+E TYR H+ SD T YR DE +E + +D
Sbjct: 258 GNDVLACLAVTKWALERARRGEGPTLVEAFTYRMGAHTTSDDPTKYRA-DEEREAWEAKD 316
Query: 182 PI 187
PI
Sbjct: 317 PI 318
>UniRef50_A3RZM3 Cluster: Pyruvate dehydrogenase E1 component alpha
subunit; n=5; Proteobacteria|Rep: Pyruvate dehydrogenase
E1 component alpha subunit - Ralstonia solanacearum
UW551
Length = 368
Score = 55.2 bits (127), Expect = 1e-06
Identities = 30/94 (31%), Positives = 48/94 (51%)
Frame = +2
Query: 2 GMDVIATREATKFAIDYCTSGKGPLLIEMETYRYSGHSMSDPGTSYRTRDEVQEVRQTRD 181
G DVIA R+A + A+D +G GP LIE +YR H+ +D T YR D V++ R+
Sbjct: 224 GNDVIAVRQAAQEALDKARAGGGPTLIEALSYRLGDHTTADDATRYRDSDIVKQA-WARE 282
Query: 182 PITSFKEKVINNQLVTPDQLKEIDAKVRKETDEA 283
PI + ++ Q +++ + +EA
Sbjct: 283 PILRLRNYLVRQNAWDKAQEEQLGRACYAQVEEA 316
>UniRef50_A0UXT3 Cluster: Pyruvate dehydrogenase; n=1; Clostridium
cellulolyticum H10|Rep: Pyruvate dehydrogenase -
Clostridium cellulolyticum H10
Length = 321
Score = 55.2 bits (127), Expect = 1e-06
Identities = 34/116 (29%), Positives = 61/116 (52%), Gaps = 2/116 (1%)
Frame = +2
Query: 2 GMDVIATREATKFAIDYCTSGKGPLLIEMETYRYSGH--SMSDPGTSYRTRDEVQEVRQT 175
G DV+ E + AI+ C G+GP L+E +YR+ GH ++ D G YR+++E + +
Sbjct: 205 GNDVLKVSEYAEKAIERCRKGEGPTLLECVSYRWKGHIGTVDDLGVGYRSQEE-YDYWIS 263
Query: 176 RDPITSFKEKVINNQLVTPDQLKEIDAKVRKETDEASKQAKADPEIPIEELSGDIY 343
+ PI +K+ + ++ K I+ ++ K +A + A P+ EEL +Y
Sbjct: 264 KCPIKWYKDYLRVRNILDDKLEKSINEEIDKLVKDAFEFAVNSPKPQPEELFDFVY 319
>UniRef50_Q3W421 Cluster: Pyruvate dehydrogenase; n=1; Frankia sp.
EAN1pec|Rep: Pyruvate dehydrogenase - Frankia sp.
EAN1pec
Length = 358
Score = 54.8 bits (126), Expect = 1e-06
Identities = 27/62 (43%), Positives = 38/62 (61%)
Frame = +2
Query: 2 GMDVIATREATKFAIDYCTSGKGPLLIEMETYRYSGHSMSDPGTSYRTRDEVQEVRQTRD 181
G DV+A T +A+++ SG+GP+LIE TYR + H+ SD + Y+ EV R RD
Sbjct: 231 GNDVLAVHAVTTWALEHARSGQGPVLIEANTYRMAPHTTSDDASRYQEAAEVAAWR-ARD 289
Query: 182 PI 187
PI
Sbjct: 290 PI 291
>UniRef50_Q1IY28 Cluster: Pyruvate dehydrogenase; n=1; Deinococcus
geothermalis DSM 11300|Rep: Pyruvate dehydrogenase -
Deinococcus geothermalis (strain DSM 11300)
Length = 361
Score = 54.8 bits (126), Expect = 1e-06
Identities = 33/123 (26%), Positives = 59/123 (47%)
Frame = +2
Query: 2 GMDVIATREATKFAIDYCTSGKGPLLIEMETYRYSGHSMSDPGTSYRTRDEVQEVRQTRD 181
G DV+AT + T A++ +G+GP LIE TYR H+++D + YR+ D +D
Sbjct: 229 GNDVLATYQVTLEAVNRARNGEGPTLIETVTYRVKPHTVADDPSRYRS-DADTAGWDAKD 287
Query: 182 PITSFKEKVINNQLVTPDQLKEIDAKVRKETDEASKQAKADPEIPIEELSGDIYYSNLEP 361
P+ + ++ +T + EI ++ E + A + A PE E+ ++
Sbjct: 288 PVRRLQTHLLTEGHLTEKEDAEITREIEAEFEAALQVADRFPEPTPAEIVDHVFAEPTPQ 347
Query: 362 FIR 370
+R
Sbjct: 348 LVR 350
>UniRef50_Q9VHB8 Cluster: CG8199-PA; n=2; Eukaryota|Rep: CG8199-PA -
Drosophila melanogaster (Fruit fly)
Length = 439
Score = 53.6 bits (123), Expect = 3e-06
Identities = 31/103 (30%), Positives = 50/103 (48%), Gaps = 4/103 (3%)
Frame = +2
Query: 2 GMDVIATREATKFAIDYCTSGKGPLLIEMETYRYSGHSMSDPGTSYRTRDEVQEVRQTRD 181
G DV A A K A +Y P++ E YR HS SD T+YR +E++
Sbjct: 294 GTDVFAVYNAMKAAREYVLKENKPVVFEALAYRVGHHSTSDDSTAYRPAEEIEIWNSVEH 353
Query: 182 PITSFKEKVIN----NQLVTPDQLKEIDAKVRKETDEASKQAK 298
PI+ K +++ ++ V + +K+I KV K+ + K+ K
Sbjct: 354 PISKLKRYMVHKGWFDETVENEYVKDIRKKVLKQIAVSEKKLK 396
>UniRef50_A3SJ75 Cluster: 2-oxoisovalerate dehydrogenase beta
subunit; n=1; Roseovarius nubinhibens ISM|Rep:
2-oxoisovalerate dehydrogenase beta subunit -
Roseovarius nubinhibens ISM
Length = 746
Score = 53.2 bits (122), Expect = 4e-06
Identities = 29/94 (30%), Positives = 50/94 (53%), Gaps = 1/94 (1%)
Frame = +2
Query: 2 GMDVIATREATKFAIDYCTSGKGPLLIEMETYRYSGHSMSDPGTSYRTRDEVQE-VRQTR 178
GMDVIA R A + A + GP+L+E TYR+ S G+++ RD+ +E R
Sbjct: 265 GMDVIAARRAMETARKIIETSGGPVLLEARTYRHLHQSGPLKGSAFGYRDKAEEDAWLAR 324
Query: 179 DPITSFKEKVINNQLVTPDQLKEIDAKVRKETDE 280
DP T+ ++++ L+T Q+ + ++ D+
Sbjct: 325 DPATTLPQQILRAGLLTEAQIDTLRSRATAAVDD 358
>UniRef50_Q9Z8N4 Cluster: Pyruvate Dehydrogenase Alpha; n=8;
Chlamydiaceae|Rep: Pyruvate Dehydrogenase Alpha -
Chlamydia pneumoniae (Chlamydophila pneumoniae)
Length = 342
Score = 52.8 bits (121), Expect = 6e-06
Identities = 31/114 (27%), Positives = 59/114 (51%)
Frame = +2
Query: 2 GMDVIATREATKFAIDYCTSGKGPLLIEMETYRYSGHSMSDPGTSYRTRDEVQEVRQTRD 181
G D+ + + A Y + P+L+E R+ GHS+SDP YR+++E+Q + + +D
Sbjct: 230 GFDLFNSLLGFREAYRYMVDTESPVLVECLCSRFRGHSISDPNL-YRSKEEMQCLFK-KD 287
Query: 182 PITSFKEKVINNQLVTPDQLKEIDAKVRKETDEASKQAKADPEIPIEELSGDIY 343
PI K+ +I +++T ++ + I + + EA AK + + L +Y
Sbjct: 288 PIVLAKDWLIRLEVLTEEEFQNIRQECKTAVLEAFSNAKLSSDPSVTTLEEGVY 341
>UniRef50_Q5SJR9 Cluster: Pyruvate dehydrogenase (Lipoamide) (EC
1.2.4.1) E1-alpha chain; n=2; Thermus thermophilus|Rep:
Pyruvate dehydrogenase (Lipoamide) (EC 1.2.4.1) E1-alpha
chain - Thermus thermophilus (strain HB8 / ATCC 27634 /
DSM 579)
Length = 346
Score = 52.8 bits (121), Expect = 6e-06
Identities = 32/114 (28%), Positives = 55/114 (48%)
Frame = +2
Query: 2 GMDVIATREATKFAIDYCTSGKGPLLIEMETYRYSGHSMSDPGTSYRTRDEVQEVRQTRD 181
G D A K A++ G+GP L+E TYR + H+ SD + YR+++E +E + +D
Sbjct: 210 GNDAFAVYLEAKKAVERARKGEGPTLLEALTYRLAPHTTSDDPSRYRSKEE-EEAWRAKD 268
Query: 182 PITSFKEKVINNQLVTPDQLKEIDAKVRKETDEASKQAKADPEIPIEELSGDIY 343
PI ++ + L + K + ++ +E A PE EE+ +Y
Sbjct: 269 PILRLRKALEGRGLWGEEAEKALLLELEEEFQRELALADEAPEPRPEEIVEHVY 322
>UniRef50_A7BPK6 Cluster: Pyruvate dehydrogenase; n=1; Beggiatoa sp.
PS|Rep: Pyruvate dehydrogenase - Beggiatoa sp. PS
Length = 331
Score = 52.8 bits (121), Expect = 6e-06
Identities = 30/116 (25%), Positives = 56/116 (48%), Gaps = 2/116 (1%)
Frame = +2
Query: 2 GMDVIATREATKFAIDYCTSGKGPLLIEMETYRYSGH--SMSDPGTSYRTRDEVQEVRQT 175
G DV+ + AI+ G+GP +E++TYR+ H D YR E+ ++
Sbjct: 215 GNDVLNVTALAREAINRTRRGEGPQFLELDTYRWLEHCGPNDDDNLGYRPAGELMSWKK- 273
Query: 176 RDPITSFKEKVINNQLVTPDQLKEIDAKVRKETDEASKQAKADPEIPIEELSGDIY 343
R P+ FK ++ +Q VT ++++++ +V E + A A P ++ +Y
Sbjct: 274 RCPVEQFKNLLLESQKVTHTEIQQVENEVLHEIEAAFSYALESPNPTSASMADKVY 329
>UniRef50_A0K283 Cluster: Pyruvate dehydrogenase; n=4;
Actinobacteria (class)|Rep: Pyruvate dehydrogenase -
Arthrobacter sp. (strain FB24)
Length = 415
Score = 52.8 bits (121), Expect = 6e-06
Identities = 26/62 (41%), Positives = 36/62 (58%)
Frame = +2
Query: 2 GMDVIATREATKFAIDYCTSGKGPLLIEMETYRYSGHSMSDPGTSYRTRDEVQEVRQTRD 181
G DVIA T++A++ GK P+LIE TYR H+ +D T YR DE + R +D
Sbjct: 265 GNDVIAVHAVTEWALERAREGKSPVLIEAFTYRVGAHTTADDPTKYRGSDEEAQWR-AKD 323
Query: 182 PI 187
P+
Sbjct: 324 PL 325
>UniRef50_Q4P2J0 Cluster: Putative uncharacterized protein; n=1;
Ustilago maydis|Rep: Putative uncharacterized protein -
Ustilago maydis (Smut fungus)
Length = 786
Score = 52.8 bits (121), Expect = 6e-06
Identities = 33/118 (27%), Positives = 54/118 (45%)
Frame = +2
Query: 2 GMDVIATREATKFAIDYCTSGKGPLLIEMETYRYSGHSMSDPGTSYRTRDEVQEVRQTRD 181
G D +A R A + A S + P+LIE TYR HS SD ++YR++ V+ +Q +
Sbjct: 625 GNDALAVRSAVQAAKSKALSEQRPVLIEAMTYRVGHHSTSDDSSAYRSKQAVESWKQMDN 684
Query: 182 PITSFKEKVINNQLVTPDQLKEIDAKVRKETDEASKQAKADPEIPIEELSGDIYYSNL 355
P+ + + + + +E A RK+ EA +A+ + L Y L
Sbjct: 685 PLHRMRNYLTDRGWWNDELEEETKAGHRKKVIEAMARAEKKKRPKLSSLFEGTYRGEL 742
>UniRef50_A6WG12 Cluster: Pyruvate dehydrogenase; n=3;
Actinomycetales|Rep: Pyruvate dehydrogenase -
Kineococcus radiotolerans SRS30216
Length = 390
Score = 52.4 bits (120), Expect = 8e-06
Identities = 32/100 (32%), Positives = 51/100 (51%)
Frame = +2
Query: 2 GMDVIATREATKFAIDYCTSGKGPLLIEMETYRYSGHSMSDPGTSYRTRDEVQEVRQTRD 181
G DV+A T+ A++ SG GP +E TYR H+ +D T YR E + R+ +D
Sbjct: 243 GNDVLAVLAVTRAALERARSGGGPTFVEAFTYRMGAHTTADDPTRYRLSAETEAWRE-KD 301
Query: 182 PITSFKEKVINNQLVTPDQLKEIDAKVRKETDEASKQAKA 301
PI F+ + + + D E +A + E DE + + +A
Sbjct: 302 PIDRFR-TYLRAEGILDD---EYEAALAAEADEFAARLRA 337
>UniRef50_A4XF89 Cluster: Dehydrogenase, E1 component; n=1;
Novosphingobium aromaticivorans DSM 12444|Rep:
Dehydrogenase, E1 component - Novosphingobium
aromaticivorans (strain DSM 12444)
Length = 315
Score = 52.4 bits (120), Expect = 8e-06
Identities = 38/115 (33%), Positives = 56/115 (48%)
Frame = +2
Query: 2 GMDVIATREATKFAIDYCTSGKGPLLIEMETYRYSGHSMSDPGTSYRTRDEVQEVRQTRD 181
G D +A EAT+ A +GKGP LIE + R GH DP YR D +R RD
Sbjct: 209 GQDAVAVWEATREAAARARAGKGPTLIEAKVTRKHGHYAGDP-QHYRDPD---YLRDYRD 264
Query: 182 PITSFKEKVINNQLVTPDQLKEIDAKVRKETDEASKQAKADPEIPIEELSGDIYY 346
P+ ++ N V +++ DA+V A + A+A PE + + D+Y+
Sbjct: 265 PLDLLAARLAGN--VAARIVEQADAEVA----AAYEAARAAPEPDVSVIERDLYH 313
>UniRef50_Q8D6Q7 Cluster: Pyruvate/2-oxoglutarate dehydrogenase
complex, dehydrogenase component, eukaryotic type, alpha
subunit; n=4; Vibrionaceae|Rep: Pyruvate/2-oxoglutarate
dehydrogenase complex, dehydrogenase component,
eukaryotic type, alpha subunit - Vibrio vulnificus
Length = 364
Score = 51.6 bits (118), Expect = 1e-05
Identities = 34/119 (28%), Positives = 61/119 (51%), Gaps = 1/119 (0%)
Frame = +2
Query: 2 GMDVIATREATKFAIDYCTSGKGPLLIEMETYRYSGHSMSDPGTSYRTRDEVQEVRQTRD 181
G DV+A +A A+D GKG LIE +YR S H+ +D + YR+ DE+++ Q +
Sbjct: 225 GNDVVAVYDAVNNALDRARKGKGATLIEAISYRLSDHTTADDASRYRSADELKQAWQ-YE 283
Query: 182 PITSFKEKVINNQLVTPDQLKEIDAKVRKETDEA-SKQAKADPEIPIEELSGDIYYSNL 355
PI + + L + ++ A +++ ++A + P+ P E + D Y++L
Sbjct: 284 PIKRLQAYLTAQGLWNEELEQQWLAHCKQQVEQAVAHYLSLPPQAP--ESAFDYLYASL 340
>UniRef50_Q4L1A7 Cluster: Pyruvate dehydrogenase E1 component alpha
subunit; n=9; Mycoplasma|Rep: Pyruvate dehydrogenase E1
component alpha subunit - Mycoplasma synoviae
Length = 374
Score = 51.6 bits (118), Expect = 1e-05
Identities = 34/126 (26%), Positives = 70/126 (55%), Gaps = 3/126 (2%)
Frame = +2
Query: 2 GMDVIATREATKFAIDYCTSGKGPLLIEMETYRYSGHSMSDPGTSYRTRDEVQEVRQTRD 181
G D++A+ + K A+++ P+L+E T+R H+ SD YRT E +E ++ +
Sbjct: 238 GNDLLASYDVIKEAVEFARKESRPVLVEFVTWRQGPHTTSDNPRVYRTETEEKE-QEVWE 296
Query: 182 PITSFKEKVINNQLVTPDQLKEIDA---KVRKETDEASKQAKADPEIPIEELSGDIYYSN 352
P+ ++ +++ +L+T ++++I A +V K+T E S + E ++E+ D Y+
Sbjct: 297 PMHRIEKYLLDRKLLTKKEIEKIWADSLEVAKKTYEESVKLN---EATLDEVF-DYTYAE 352
Query: 353 LEPFIR 370
L P ++
Sbjct: 353 LTPELK 358
>UniRef50_A5IXN2 Cluster: Pyruvate dehydrogenase E1 component,
alphasubunit; n=1; Mycoplasma agalactiae|Rep: Pyruvate
dehydrogenase E1 component, alphasubunit - Mycoplasma
agalactiae
Length = 363
Score = 51.6 bits (118), Expect = 1e-05
Identities = 28/99 (28%), Positives = 50/99 (50%)
Frame = +2
Query: 2 GMDVIATREATKFAIDYCTSGKGPLLIEMETYRYSGHSMSDPGTSYRTRDEVQEVRQTRD 181
G D+IA E + Y G GP+L+EM T+R H+ SD YR+R E++ ++ +
Sbjct: 230 GNDLIAVNEVMEEVYYYVREGNGPVLVEMVTWRQGQHTTSDNPRVYRSR-ELEMEKEKWE 288
Query: 182 PITSFKEKVINNQLVTPDQLKEIDAKVRKETDEASKQAK 298
P + +++ +L+T + +K +E A +K
Sbjct: 289 PFHRIEAYLLSEKLITEEDIKVWSEAAAEEAKAAYALSK 327
>UniRef50_A1UJ85 Cluster: Pyruvate dehydrogenase; n=16;
Mycobacterium|Rep: Pyruvate dehydrogenase -
Mycobacterium sp. (strain KMS)
Length = 356
Score = 51.6 bits (118), Expect = 1e-05
Identities = 35/116 (30%), Positives = 54/116 (46%), Gaps = 1/116 (0%)
Frame = +2
Query: 2 GMDVIATREATKFAIDYCTSGKGPLLIEMETYRYSGHSMSDPGTSYRTRDEVQEVRQTRD 181
G DV+A A +G GP LIE TYR H+ SD T YR + EV R RD
Sbjct: 222 GNDVLACFAVMSEAAARARAGGGPTLIEAVTYRLGPHTTSDDPTRYRDQSEVDRWR-ARD 280
Query: 182 PITSFKEKVINNQLVTPDQLKE-IDAKVRKETDEASKQAKADPEIPIEELSGDIYY 346
PI ++ + V ++L+E + A+ ++ E P+ + E+ +Y+
Sbjct: 281 PIPRYR-TYLQGAGVWSERLEERVAARSKRLRAELRDAVVGAPDFDVSEVFDTVYH 335
>UniRef50_A0LFE6 Cluster: Pyruvate dehydrogenase; n=1;
Syntrophobacter fumaroxidans MPOB|Rep: Pyruvate
dehydrogenase - Syntrophobacter fumaroxidans (strain DSM
10017 / MPOB)
Length = 320
Score = 51.6 bits (118), Expect = 1e-05
Identities = 31/114 (27%), Positives = 58/114 (50%)
Frame = +2
Query: 2 GMDVIATREATKFAIDYCTSGKGPLLIEMETYRYSGHSMSDPGTSYRTRDEVQEVRQTRD 181
G D A + A +G+GP LIE +TYR GH SD Y+ +E+ ++ R
Sbjct: 208 GNDARVVYAAAERARARAVAGEGPSLIECKTYRCRGHGESD-HQLYQPPEEIASWKE-RC 265
Query: 182 PITSFKEKVINNQLVTPDQLKEIDAKVRKETDEASKQAKADPEIPIEELSGDIY 343
P+ +++V+ +L+ LK ++ ++ + ++A + A+ P E+ D+Y
Sbjct: 266 PLPRLRDEVLAQELLDEKALKSMEDEISRIVEDAVRFAEESPWPDPEDALSDVY 319
>UniRef50_A0JUQ5 Cluster: Pyruvate dehydrogenase; n=4;
Actinobacteria (class)|Rep: Pyruvate dehydrogenase -
Arthrobacter sp. (strain FB24)
Length = 392
Score = 51.6 bits (118), Expect = 1e-05
Identities = 30/100 (30%), Positives = 51/100 (51%)
Frame = +2
Query: 2 GMDVIATREATKFAIDYCTSGKGPLLIEMETYRYSGHSMSDPGTSYRTRDEVQEVRQTRD 181
G DV+A AT+ A++ G GP IE TYR H+ +D T YR +E+++ +D
Sbjct: 246 GNDVLAVMAATREALERARHGGGPTFIEAVTYRMGPHTTADDPTRYRDANELED-WAAKD 304
Query: 182 PITSFKEKVINNQLVTPDQLKEIDAKVRKETDEASKQAKA 301
PI + + L+T E++ +V + D ++ +A
Sbjct: 305 PIARVRGLLERKGLLT----DELEGRVAAKADAVARDMRA 340
>UniRef50_Q295J7 Cluster: GA20891-PA; n=7; Coelomata|Rep: GA20891-PA
- Drosophila pseudoobscura (Fruit fly)
Length = 439
Score = 51.6 bits (118), Expect = 1e-05
Identities = 30/103 (29%), Positives = 49/103 (47%), Gaps = 4/103 (3%)
Frame = +2
Query: 2 GMDVIATREATKFAIDYCTSGKGPLLIEMETYRYSGHSMSDPGTSYRTRDEVQEVRQTRD 181
G DV A A K A +Y P++ E YR HS SD T+YR+ +E++
Sbjct: 294 GTDVFAVYNAMKEAREYVLRENKPVVFEALAYRVGHHSTSDDSTAYRSTEEIEVWNSVEH 353
Query: 182 PITSFKEKVIN----NQLVTPDQLKEIDAKVRKETDEASKQAK 298
PI+ K +++ ++ +KE+ KV K+ + K+ K
Sbjct: 354 PISKLKRYMVHKGWFDEAEETAYIKEVRKKVLKQIAVSEKKLK 396
>UniRef50_A7RZV6 Cluster: Predicted protein; n=6; Eumetazoa|Rep:
Predicted protein - Nematostella vectensis
Length = 444
Score = 51.6 bits (118), Expect = 1e-05
Identities = 32/114 (28%), Positives = 54/114 (47%)
Frame = +2
Query: 2 GMDVIATREATKFAIDYCTSGKGPLLIEMETYRYSGHSMSDPGTSYRTRDEVQEVRQTRD 181
G D+ A TK A + + P+L+E TYR HS SD + YR+ EV +
Sbjct: 298 GNDIFAVYNVTKKAREIAVNENRPVLVEAMTYRIGHHSTSDDSSVYRSLKEVNYWDKEDH 357
Query: 182 PITSFKEKVINNQLVTPDQLKEIDAKVRKETDEASKQAKADPEIPIEELSGDIY 343
PI+ + + + DQ ++ + R + +A A+ + P++EL D+Y
Sbjct: 358 PISRLRYYMEDKGWWDQDQEQQWKKEARLQVMQAFADAEKALKPPVKELFLDVY 411
>UniRef50_Q8YDW3 Cluster: 2-OXOISOVALERATE DEHYDROGENASE BETA
SUBUNIT; n=10; Bacteria|Rep: 2-OXOISOVALERATE
DEHYDROGENASE BETA SUBUNIT - Brucella melitensis
Length = 729
Score = 51.2 bits (117), Expect = 2e-05
Identities = 32/99 (32%), Positives = 52/99 (52%), Gaps = 2/99 (2%)
Frame = +2
Query: 2 GMDVIATREATKFAIDYCTSGKGPLLIEMETYRYSGHSMSDPGTS--YRTRDEVQEVRQT 175
GMD IA A++ A +G GP +IE + YRY + PG++ YR++DE E R
Sbjct: 250 GMDPIAVWLASEEANAIMRAGNGPTIIEADVYRYFHQNGPLPGSAFGYRSKDEEAEWR-G 308
Query: 176 RDPITSFKEKVINNQLVTPDQLKEIDAKVRKETDEASKQ 292
RDP+ + + ++ Q + D +K + + DE + Q
Sbjct: 309 RDPLDALAKTLLERQALGEDAIKALRERCVSLMDEVAGQ 347
>UniRef50_A6UDY5 Cluster: Dehydrogenase E1 component; n=2;
Alphaproteobacteria|Rep: Dehydrogenase E1 component -
Sinorhizobium medicae WSM419
Length = 342
Score = 51.2 bits (117), Expect = 2e-05
Identities = 32/114 (28%), Positives = 55/114 (48%)
Frame = +2
Query: 2 GMDVIATREATKFAIDYCTSGKGPLLIEMETYRYSGHSMSDPGTSYRTRDEVQEVRQTRD 181
G+DV + A ++ +D +GK P + +E YR+ GH+ D + YR E E R+ +D
Sbjct: 209 GLDVEEVQAAARWLVDEARAGK-PGFLSVEVYRFFGHARMDK-SPYREEAEELEGRK-KD 265
Query: 182 PITSFKEKVINNQLVTPDQLKEIDAKVRKETDEASKQAKADPEIPIEELSGDIY 343
P+ + K+I+ + L E+D + E D A P+ + D+Y
Sbjct: 266 PVLFARNKLIDTGIEEERILDELDKAIAAEMDATIDFAVESKAPPLGSMFKDVY 319
>UniRef50_A0JY23 Cluster: Pyruvate dehydrogenase; n=2;
Arthrobacter|Rep: Pyruvate dehydrogenase - Arthrobacter
sp. (strain FB24)
Length = 359
Score = 51.2 bits (117), Expect = 2e-05
Identities = 34/123 (27%), Positives = 59/123 (47%)
Frame = +2
Query: 2 GMDVIATREATKFAIDYCTSGKGPLLIEMETYRYSGHSMSDPGTSYRTRDEVQEVRQTRD 181
G DV+A +AT+ A + +G GP+LIE TYR HS SD YR+ +E ++ D
Sbjct: 226 GNDVVAVVDATRRAFAHARAGHGPVLIEAMTYRRGPHSTSDDPGRYRSLNEERD-DAGED 284
Query: 182 PITSFKEKVINNQLVTPDQLKEIDAKVRKETDEASKQAKADPEIPIEELSGDIYYSNLEP 361
P+ F++ ++ + + E A + E + +A P E+ D+ + P
Sbjct: 285 PLERFRKTLLADGVADEAFFAEALAAAKAEEEHIRAGIQALGSRPGTEMF-DLVFQETTP 343
Query: 362 FIR 370
++
Sbjct: 344 ALQ 346
>UniRef50_Q83FF2 Cluster: Pyruvate dehydrogenase E1 component alpha
subunit; n=2; Tropheryma whipplei|Rep: Pyruvate
dehydrogenase E1 component alpha subunit - Tropheryma
whipplei (strain Twist) (Whipple's bacillus)
Length = 370
Score = 50.8 bits (116), Expect = 2e-05
Identities = 26/54 (48%), Positives = 31/54 (57%)
Frame = +2
Query: 2 GMDVIATREATKFAIDYCTSGKGPLLIEMETYRYSGHSMSDPGTSYRTRDEVQE 163
G DVIA + +D SGKGP LIE TYR H+ SD T YR+ DE +E
Sbjct: 238 GNDVIAAYAVVREYMDRARSGKGPHLIEAFTYRLGAHTTSDDPTRYRSEDEHRE 291
>UniRef50_Q2ITF8 Cluster: Acetoin dehydrogenase (TPP-dependent)
alpha chain; n=1; Rhodopseudomonas palustris HaA2|Rep:
Acetoin dehydrogenase (TPP-dependent) alpha chain -
Rhodopseudomonas palustris (strain HaA2)
Length = 323
Score = 50.8 bits (116), Expect = 2e-05
Identities = 34/116 (29%), Positives = 52/116 (44%), Gaps = 2/116 (1%)
Frame = +2
Query: 2 GMDVIATREATKFAIDYCTSGKGPLLIEMETYRYSGHSMS--DPGTSYRTRDEVQEVRQT 175
G D A A + +G+GP E ETYR+ H D YR+ E E +
Sbjct: 205 GNDARAVHAALSEGVAAIRAGEGPRFYEFETYRWREHCGPNYDNDIGYRSAAEY-EAWKL 263
Query: 176 RDPITSFKEKVINNQLVTPDQLKEIDAKVRKETDEASKQAKADPEIPIEELSGDIY 343
RDP+ + + +I +V+ + + A++ E DEA A+A P E D+Y
Sbjct: 264 RDPVPALQRALIGEGVVSESGIAAMQAEIDAEIDEAFAFAEASPFPDAGEAFTDVY 319
>UniRef50_A0DAM1 Cluster: Chromosome undetermined scaffold_43, whole
genome shotgun sequence; n=3; Oligohymenophorea|Rep:
Chromosome undetermined scaffold_43, whole genome
shotgun sequence - Paramecium tetraurelia
Length = 406
Score = 50.8 bits (116), Expect = 2e-05
Identities = 34/117 (29%), Positives = 49/117 (41%), Gaps = 3/117 (2%)
Frame = +2
Query: 2 GMDVIATREATKFAIDYCTSGKGPLLIEMETYRYSGHSMSDPGTSYRTRDEVQEVRQTRD 181
G D++A K+A + K P IE TYR HS SD YR+++E+ + +
Sbjct: 257 GNDLLAVYNGVKYAREQIIKNKEPFFIEFITYRIGDHSTSDHSVLYRSQEEIDSWKSGNN 316
Query: 182 PITS---FKEKVINNQLVTPDQLKEIDAKVRKETDEASKQAKADPEIPIEELSGDIY 343
PI F +K Q D +I VR A K I++L D+Y
Sbjct: 317 PINRLGLFLKKQGLRQF-NDDHDNQIRKDVRNRVIAALKHGSEQQSPSIQDLFTDVY 372
>UniRef50_Q9YBC0 Cluster: Pyruvate dehydrogenase E1 component, alpha
subunit; n=1; Aeropyrum pernix|Rep: Pyruvate
dehydrogenase E1 component, alpha subunit - Aeropyrum
pernix
Length = 377
Score = 50.8 bits (116), Expect = 2e-05
Identities = 27/114 (23%), Positives = 55/114 (48%)
Frame = +2
Query: 2 GMDVIATREATKFAIDYCTSGKGPLLIEMETYRYSGHSMSDPGTSYRTRDEVQEVRQTRD 181
G DV+ + A + G GP LIE TYR H+ +D + YRT +E + + + +
Sbjct: 235 GNDVMVVYKIVSDAAEKARRGGGPTLIEAVTYRLGPHTTADDPSRYRTSEE-ERIMERYE 293
Query: 182 PITSFKEKVINNQLVTPDQLKEIDAKVRKETDEASKQAKADPEIPIEELSGDIY 343
P+ ++ + + ++T + I+ + + +E ++ A P +P ++Y
Sbjct: 294 PLRRMRKFMESMGILTEKEALSIEEEWNSKVEEIVRKVLAKPPLPENVFFQNVY 347
>UniRef50_Q5KGR5 Cluster: Branched-chain alpha-keto acid
dehydrogenase E1-alpha subunit, putative; n=2;
Filobasidiella neoformans|Rep: Branched-chain alpha-keto
acid dehydrogenase E1-alpha subunit, putative -
Cryptococcus neoformans (Filobasidiella neoformans)
Length = 504
Score = 50.4 bits (115), Expect = 3e-05
Identities = 30/114 (26%), Positives = 56/114 (49%)
Frame = +2
Query: 2 GMDVIATREATKFAIDYCTSGKGPLLIEMETYRYSGHSMSDPGTSYRTRDEVQEVRQTRD 181
G D +A A A GK +L+E TYR HS SD + YR +EV+E +
Sbjct: 336 GNDALAVYAAVCEARKRAVEGKKGVLVEAMTYRVGHHSTSDDSSMYRAIEEVKEWSVVDN 395
Query: 182 PITSFKEKVINNQLVTPDQLKEIDAKVRKETDEASKQAKADPEIPIEELSGDIY 343
PI + +++ + + ++ K + K + + +A +A+ P+ + E+ D++
Sbjct: 396 PIHRLRSYLVSKKWWSEEEEKALLKKNKADVLKAFSRAEKLPKPKLGEMFNDVW 449
>UniRef50_UPI00005103B4 Cluster: COG1071: Pyruvate/2-oxoglutarate
dehydrogenase complex, dehydrogenase (E1) component,
eukaryotic type, alpha subunit; n=1; Brevibacterium
linens BL2|Rep: COG1071: Pyruvate/2-oxoglutarate
dehydrogenase complex, dehydrogenase (E1) component,
eukaryotic type, alpha subunit - Brevibacterium linens
BL2
Length = 368
Score = 50.0 bits (114), Expect = 4e-05
Identities = 32/114 (28%), Positives = 48/114 (42%)
Frame = +2
Query: 2 GMDVIATREATKFAIDYCTSGKGPLLIEMETYRYSGHSMSDPGTSYRTRDEVQEVRQTRD 181
G DV A A A++ +G GP LIE TYR H+ SD T YR +EV+ +Q D
Sbjct: 232 GNDVAAVFAAVAAALERGRNGDGPTLIECLTYRMESHTNSDDPTKYRDSEEVEHWKQF-D 290
Query: 182 PITSFKEKVINNQLVTPDQLKEIDAKVRKETDEASKQAKADPEIPIEELSGDIY 343
PI ++ + + + E+ + E+ EL +Y
Sbjct: 291 PIDRLEKYLRTTGALDDSTVAEVAEAAETLAASVRDAMNQEAEVDPRELFAHVY 344
>UniRef50_Q11G20 Cluster: Twin-arginine translocation pathway
signal; n=2; Proteobacteria|Rep: Twin-arginine
translocation pathway signal - Mesorhizobium sp. (strain
BNC1)
Length = 375
Score = 50.0 bits (114), Expect = 4e-05
Identities = 37/123 (30%), Positives = 59/123 (47%), Gaps = 15/123 (12%)
Frame = +2
Query: 2 GMDVIATREATKFAIDYCTSGKGPLLIEMETYRYSGH---SMSDPG------------TS 136
G DVI A K A+D +G+GP LIE +TYRY H + PG +S
Sbjct: 237 GQDVIQVYNAAKTAVDRARAGEGPTLIEAKTYRYYNHWGAPGAKPGELGAFGYDPLAISS 296
Query: 137 YRTRDEVQEVRQTRDPITSFKEKVINNQLVTPDQLKEIDAKVRKETDEASKQAKADPEIP 316
+R E++ Q RDP+ + ++N ++ + EI+A V+++ +A A P
Sbjct: 297 FRPERELRSWMQ-RDPVRIAHDILVNWGVIDHAKAAEIEASVKQDVADAFAWAAEQPLCK 355
Query: 317 IEE 325
E+
Sbjct: 356 AED 358
>UniRef50_Q13GQ3 Cluster: Putative 2-oxo acid dehydrogenase alpha
subunit; n=1; Burkholderia xenovorans LB400|Rep:
Putative 2-oxo acid dehydrogenase alpha subunit -
Burkholderia xenovorans (strain LB400)
Length = 334
Score = 49.6 bits (113), Expect = 5e-05
Identities = 33/114 (28%), Positives = 53/114 (46%)
Frame = +2
Query: 2 GMDVIATREATKFAIDYCTSGKGPLLIEMETYRYSGHSMSDPGTSYRTRDEVQEVRQTRD 181
G D +A EA+ A SG GP ++E T+R GH DP YR E+ + +D
Sbjct: 217 GDDAVAVSEASGIAAAAARSGAGPFVLECVTHRVRGHYEGDP-QKYRDPTELDGL-AGKD 274
Query: 182 PITSFKEKVINNQLVTPDQLKEIDAKVRKETDEASKQAKADPEIPIEELSGDIY 343
P+ + + V+ ++ +I V + A + A+AD +E S D+Y
Sbjct: 275 PLKRMHTH-LESAGVSASEIDQIGRAVLTRVEAAIEAARADALPDFDEASRDVY 327
>UniRef50_Q8EVQ2 Cluster: Pyruvate dehydrogenase E1 component
subunit alpha; n=1; Mycoplasma penetrans|Rep: Pyruvate
dehydrogenase E1 component subunit alpha - Mycoplasma
penetrans
Length = 359
Score = 49.2 bits (112), Expect = 7e-05
Identities = 29/109 (26%), Positives = 55/109 (50%)
Frame = +2
Query: 2 GMDVIATREATKFAIDYCTSGKGPLLIEMETYRYSGHSMSDPGTSYRTRDEVQEVRQTRD 181
G + A+ +A + A Y K P+L+E TYR H+ SD YR+ +E + ++ +D
Sbjct: 225 GNCLFASVDAIRAARAYVLENKKPILVEFVTYRKGPHTTSDNPRIYRS-EEYECEQEKKD 283
Query: 182 PITSFKEKVINNQLVTPDQLKEIDAKVRKETDEASKQAKADPEIPIEEL 328
PI + + N L+ + +I K E +EA K ++ + ++++
Sbjct: 284 PILRLERWMAQNGLLDESKKAQIIEKADAEVEEAYKIMESKLSVSVDDV 332
>UniRef50_Q479Q2 Cluster: Dehydrogenase, E1 component; n=2;
Rhodocyclaceae|Rep: Dehydrogenase, E1 component -
Dechloromonas aromatica (strain RCB)
Length = 320
Score = 48.4 bits (110), Expect = 1e-04
Identities = 37/114 (32%), Positives = 54/114 (47%)
Frame = +2
Query: 2 GMDVIATREATKFAIDYCTSGKGPLLIEMETYRYSGHSMSDPGTSYRTRDEVQEVRQTRD 181
G DV A EAT+ A + P+L+E+ TYR GH D Y + E+ RD
Sbjct: 208 GNDVFAVLEATREAATQVRDTRRPVLLEVLTYRTRGHFEPD-DQGYVDKAEL-AAWLARD 265
Query: 182 PITSFKEKVINNQLVTPDQLKEIDAKVRKETDEASKQAKADPEIPIEELSGDIY 343
PI ++++I + + E+ A+V A A A P IEEL+ D+Y
Sbjct: 266 PIALCRDRLIADGHLDVAADAELAARVEASIAAAVAFAAASPFPSIEELTLDVY 319
>UniRef50_Q9HNV6 Cluster: Pyruvate dehydrogenase alpha subunit; n=1;
Halobacterium salinarum|Rep: Pyruvate dehydrogenase
alpha subunit - Halobacterium salinarium (Halobacterium
halobium)
Length = 322
Score = 48.4 bits (110), Expect = 1e-04
Identities = 30/114 (26%), Positives = 52/114 (45%)
Frame = +2
Query: 2 GMDVIATREATKFAIDYCTSGKGPLLIEMETYRYSGHSMSDPGTSYRTRDEVQEVRQTRD 181
G D +A E A+ G P+L+E TYR H+ SD YR +E +T D
Sbjct: 182 GNDPLAVYETVTDALAGARDGT-PILVESLTYRQGAHTTSDDPDRYRPEEEDLPAWRTAD 240
Query: 182 PITSFKEKVINNQLVTPDQLKEIDAKVRKETDEASKQAKADPEIPIEELSGDIY 343
P+ + + + + ++ ++E E D+A + A+A ++EL +Y
Sbjct: 241 PVDRYADYLHDQGVIDAGFVEECFDAAADEIDDAVETAEAAGAPAVDELFDHVY 294
>UniRef50_A5V557 Cluster: Pyruvate dehydrogenase; n=1; Sphingomonas
wittichii RW1|Rep: Pyruvate dehydrogenase - Sphingomonas
wittichii RW1
Length = 331
Score = 48.0 bits (109), Expect = 2e-04
Identities = 34/118 (28%), Positives = 54/118 (45%)
Frame = +2
Query: 2 GMDVIATREATKFAIDYCTSGKGPLLIEMETYRYSGHSMSDPGTSYRTRDEVQEVRQTRD 181
G DV A A A+ +G GP L+E +TYRY+ H+++ EV E R+ RD
Sbjct: 208 GQDVDAVEAAVAEAVGRARTGGGPTLVETKTYRYADHAVNMGRVLLDRGGEVDEWRK-RD 266
Query: 182 PITSFKEKVINNQLVTPDQLKEIDAKVRKETDEASKQAKADPEIPIEELSGDIYYSNL 355
P+ ++ K+I L I+ +V E +A + A+ E D++ L
Sbjct: 267 PLALYRAKLIAGGTAAA-LLDAIEREVADEVADALQFARDSAWPEQAEAFDDVFVDRL 323
>UniRef50_Q00TN9 Cluster: Pyruvate dehydrogenase E1 component beta;
n=3; Ostreococcus|Rep: Pyruvate dehydrogenase E1
component beta - Ostreococcus tauri
Length = 835
Score = 48.0 bits (109), Expect = 2e-04
Identities = 33/107 (30%), Positives = 51/107 (47%), Gaps = 8/107 (7%)
Frame = +2
Query: 65 KGPLLIEMETYRYSGHSMSDPGTSYRTRDEVQEVRQTRDPITSFKEKVINNQLVTPDQLK 244
KGP ++++ T+R++GHS +DP +DE + R DPI F+ N+ LK
Sbjct: 363 KGPAILQVHTFRFNGHSPADPEHERNRKDEKRWARAECDPIKIFE----NSADAARIDLK 418
Query: 245 EIDAKVRKETDEASKQAKADP--------EIPIEELSGDIYYSNLEP 361
+ + + ET A A A P E+ + SG + YS EP
Sbjct: 419 KETERAKAETQRALAFADASPPPPPGLAAELEYPDPSGAVDYSAREP 465
>UniRef50_Q4N1L6 Cluster: Branched-chain alpha keto-acid
dehydrogenase, putative; n=3; Piroplasmida|Rep:
Branched-chain alpha keto-acid dehydrogenase, putative -
Theileria parva
Length = 464
Score = 47.6 bits (108), Expect = 2e-04
Identities = 21/53 (39%), Positives = 30/53 (56%)
Frame = +2
Query: 2 GMDVIATREATKFAIDYCTSGKGPLLIEMETYRYSGHSMSDPGTSYRTRDEVQ 160
G D+ A+ ATK+ +YC P++IE TYR HS SD + YR + E +
Sbjct: 314 GNDLFASYMATKYCREYCVKHSTPIVIEYMTYRIGHHSTSDESSQYRGKGEFE 366
>UniRef50_Q8U4T5 Cluster: 2-oxo acid dehydrogenase subunit E1; n=1;
Haloferax volcanii|Rep: 2-oxo acid dehydrogenase subunit
E1 - Halobacterium volcanii (Haloferax volcanii)
Length = 353
Score = 47.6 bits (108), Expect = 2e-04
Identities = 31/101 (30%), Positives = 45/101 (44%)
Frame = +2
Query: 8 DVIATREATKFAIDYCTSGKGPLLIEMETYRYSGHSMSDPGTSYRTRDEVQEVRQTRDPI 187
D A EA A+ G GP LIE++ +R GH M D +YR ++ +Q RD I
Sbjct: 217 DATAVYEAAGEAVMRARDGNGPTLIEVQVHRRMGHFMGD-AEAYRPEADIDRAKQ-RDSI 274
Query: 188 TSFKEKVINNQLVTPDQLKEIDAKVRKETDEASKQAKADPE 310
+ + VT D + E+ + + A AK PE
Sbjct: 275 ERLAAD-LRSHGVTDDDIDEMRERAHGRVEAAISWAKEQPE 314
>UniRef50_Q8YDG0 Cluster: 2-OXOISOVALERATE DEHYDROGENASE BETA
SUBUNIT; n=3; Brucella|Rep: 2-OXOISOVALERATE
DEHYDROGENASE BETA SUBUNIT - Brucella melitensis
Length = 725
Score = 47.2 bits (107), Expect = 3e-04
Identities = 28/99 (28%), Positives = 51/99 (51%), Gaps = 2/99 (2%)
Frame = +2
Query: 2 GMDVIATREATKFAIDYCTSGKGPLLIEMETYRYSGHSMSDPGT--SYRTRDEVQEVRQT 175
GMD+++ +A + A GP++IE + YRY S S G+ YRTR+E +E + +
Sbjct: 251 GMDILSVHQAMREACRIIEEEGGPVVIEAQCYRYLHQSGSKSGSDFGYRTREEEEEWK-S 309
Query: 176 RDPITSFKEKVINNQLVTPDQLKEIDAKVRKETDEASKQ 292
RDPI + ++ + + ++D +V A ++
Sbjct: 310 RDPIALAERRLKELGIAGDAEFLKLDERVTAAVQAAGER 348
>UniRef50_Q4Y3F8 Cluster: Branched-chain alpha keto-acid
dehydrogenase, putative; n=7; Plasmodium|Rep:
Branched-chain alpha keto-acid dehydrogenase, putative -
Plasmodium chabaudi
Length = 432
Score = 47.2 bits (107), Expect = 3e-04
Identities = 34/95 (35%), Positives = 46/95 (48%), Gaps = 5/95 (5%)
Frame = +2
Query: 2 GMDVIATREATKFAIDYCTSGKGPLLIEMETYRYSGHSMSDPGTSYRTRDEVQE-VRQTR 178
G D+ A+ ATK D C P+ +E +YRY HS SD T YR ++E ++
Sbjct: 285 GNDLFASYLATKKMRDICIQESKPVFMEFMSYRYGHHSTSDDSTLYRPKEENDAWKKEGV 344
Query: 179 DPITSFKEKVINNQLVT--PDQL--KEIDAKVRKE 271
PI+ + N L T DQL K + KV KE
Sbjct: 345 HPISRLFLYLKNKNLYTDNEDQLHRKSVKEKVLKE 379
>UniRef50_P09060 Cluster: 2-oxoisovalerate dehydrogenase subunit
alpha; n=68; Proteobacteria|Rep: 2-oxoisovalerate
dehydrogenase subunit alpha - Pseudomonas putida
Length = 410
Score = 47.2 bits (107), Expect = 3e-04
Identities = 30/99 (30%), Positives = 46/99 (46%)
Frame = +2
Query: 2 GMDVIATREATKFAIDYCTSGKGPLLIEMETYRYSGHSMSDPGTSYRTRDEVQEVRQTRD 181
G D +A A+++A + G GP LIE TYR HS SD + YR D+ D
Sbjct: 276 GNDFVAVYAASRWAAERARRGLGPSLIEWVTYRAGPHSTSDDPSKYRPADDWSHF-PLGD 334
Query: 182 PITSFKEKVINNQLVTPDQLKEIDAKVRKETDEASKQAK 298
PI K+ +I + ++ + A+ A K+A+
Sbjct: 335 PIARLKQHLIKIGHWSEEEHQATTAEFEAAVIAAQKEAE 373
>UniRef50_Q0MX87 Cluster: Acetoin dehydrogenase alpha-subunit; n=2;
Bacteria|Rep: Acetoin dehydrogenase alpha-subunit -
consortium cosmid clone pGZ1
Length = 344
Score = 46.8 bits (106), Expect = 4e-04
Identities = 33/108 (30%), Positives = 53/108 (49%)
Frame = +2
Query: 2 GMDVIATREATKFAIDYCTSGKGPLLIEMETYRYSGHSMSDPGTSYRTRDEVQEVRQTRD 181
GMDV+A A + A+ +G+GP L+ +TYR++GH DP +YR E+ + D
Sbjct: 225 GMDVVAVWRAARDAVASVRAGEGPRLLHAKTYRFTGHVSVDP-AAYRDPGELAAAMED-D 282
Query: 182 PITSFKEKVINNQLVTPDQLKEIDAKVRKETDEASKQAKADPEIPIEE 325
P+ + + + V D ++ R+E A A A E P +E
Sbjct: 283 PLLVARVR-LQASGVAGDAVEAAMRAAREEVAAAVASADA-AEWPTQE 328
>UniRef50_A4X7T3 Cluster: Dehydrogenase, E1 component; n=3;
Actinomycetales|Rep: Dehydrogenase, E1 component -
Salinispora tropica CNB-440
Length = 323
Score = 46.8 bits (106), Expect = 4e-04
Identities = 32/105 (30%), Positives = 52/105 (49%), Gaps = 2/105 (1%)
Frame = +2
Query: 2 GMDVIATREATKFAIDYCTSGKGPLLIEMETYRYSGHSMSDPGT--SYRTRDEVQEVRQT 175
G D A + T A+ +G GP +E +TYR+ H + YR+ +EV+ R +
Sbjct: 204 GQDPAAVQATTAAALTRMRAGGGPEFLEAQTYRFDAHHTFEHAVRLDYRSVEEVERGR-S 262
Query: 176 RDPITSFKEKVINNQLVTPDQLKEIDAKVRKETDEASKQAKADPE 310
RDP+ ++ ++L ++ K +DA V D A +A A PE
Sbjct: 263 RDPV-----RIAGSRLSATERAK-VDADVEAVLDAAVAEALAAPE 301
>UniRef50_Q83X26 Cluster: Probable pyruvate dehydrogenase
alpha-subunit; n=1; Streptomyces rochei|Rep: Probable
pyruvate dehydrogenase alpha-subunit - Streptomyces
rochei (Streptomyces parvullus)
Length = 326
Score = 46.4 bits (105), Expect = 5e-04
Identities = 39/130 (30%), Positives = 56/130 (43%), Gaps = 2/130 (1%)
Frame = +2
Query: 2 GMDVIATREATKFAIDYCTSGKGPLLIEMETYRYSGHSMS--DPGTSYRTRDEVQEVRQT 175
G DV A A A+++C SG GP +E++TYR+ H D R DEV +
Sbjct: 204 GNDVAAVHAAAVTAVEHCRSGTGPYFLELDTYRWREHVGPGWDHECGARRPDEVLSWTK- 262
Query: 176 RDPITSFKEKVINNQLVTPDQLKEIDAKVRKETDEASKQAKADPEIPIEELSGDIYYSNL 355
R PI + + + + + + R ET A A+A P +E+L Y
Sbjct: 263 RCPIRRAADALRGADPDVDEWITAWEREFRAETHAAIAAAEAAPFPRVEDLLVGTYGD-- 320
Query: 356 EPFIRGTHPG 385
RGTH G
Sbjct: 321 ----RGTHAG 326
>UniRef50_Q1LFS5 Cluster: Dehydrogenase, E1 component; n=22;
Proteobacteria|Rep: Dehydrogenase, E1 component -
Ralstonia metallidurans (strain CH34 / ATCC 43123 / DSM
2839)
Length = 367
Score = 46.4 bits (105), Expect = 5e-04
Identities = 24/67 (35%), Positives = 36/67 (53%)
Frame = +2
Query: 2 GMDVIATREATKFAIDYCTSGKGPLLIEMETYRYSGHSMSDPGTSYRTRDEVQEVRQTRD 181
G DVIA R+ AI++ G GP LIE +YR H+ +D + YR V+E + +
Sbjct: 224 GNDVIAVRQRVGAAIEHARHGGGPTLIEAVSYRLGDHTTADDASRYRDEASVKEAWRC-E 282
Query: 182 PITSFKE 202
PI ++
Sbjct: 283 PIIRLRD 289
>UniRef50_A3PXW7 Cluster: Transketolase domain protein; n=4;
Mycobacterium|Rep: Transketolase domain protein -
Mycobacterium sp. (strain JLS)
Length = 721
Score = 46.4 bits (105), Expect = 5e-04
Identities = 25/104 (24%), Positives = 51/104 (49%)
Frame = +2
Query: 2 GMDVIATREATKFAIDYCTSGKGPLLIEMETYRYSGHSMSDPGTSYRTRDEVQEVRQTRD 181
G D+ AT E T+ A ++ + + P + + T R GH+ SD YR DE+ RD
Sbjct: 250 GTDLAATIETTRAAAEFVRTHRRPAFLHLSTVRLMGHAGSDYEPGYRRPDEI-VADFDRD 308
Query: 182 PITSFKEKVINNQLVTPDQLKEIDAKVRKETDEASKQAKADPEI 313
P+ + ++ +++P ++ E R++ + + + P++
Sbjct: 309 PVLCAAKALVAQGILSPVEVLERYEATRRQVLDMAAEVMDAPQL 352
>UniRef50_A4F1Y5 Cluster: Branched-chain alpha-keto acid
decarboxylase; n=1; Streptomyces virginiae|Rep:
Branched-chain alpha-keto acid decarboxylase -
Streptomyces virginiae
Length = 677
Score = 45.6 bits (103), Expect = 9e-04
Identities = 25/114 (21%), Positives = 50/114 (43%)
Frame = +2
Query: 2 GMDVIATREATKFAIDYCTSGKGPLLIEMETYRYSGHSMSDPGTSYRTRDEVQEVRQTRD 181
G D A A + +G+GP ++ R H+ SD YRT+DE+ + RD
Sbjct: 228 GSDPDAVHAAAAAVLPDVRAGRGPAVLWCRLDRLDSHTSSDDQRLYRTKDELAAM---RD 284
Query: 182 PITSFKEKVINNQLVTPDQLKEIDAKVRKETDEASKQAKADPEIPIEELSGDIY 343
P+ F +++ + P ++ A++ + +E + +P E+ ++
Sbjct: 285 PVALFTDRLEAEGTIVPGWADQVRARLADDVEEVFDRVAGEPSADPGEVMDHLF 338
>UniRef50_Q9Z9E8 Cluster: (Pyruvate) Oxoisovalerate Dehydrogenase
Alpha/Beta Fusion ((Pyruvate) oxoisovalerate
dehydrogenase alpha and beta fusion); n=7;
Chlamydiaceae|Rep: (Pyruvate) Oxoisovalerate
Dehydrogenase Alpha/Beta Fusion ((Pyruvate)
oxoisovalerate dehydrogenase alpha and beta fusion) -
Chlamydia pneumoniae (Chlamydophila pneumoniae)
Length = 678
Score = 45.2 bits (102), Expect = 0.001
Identities = 27/102 (26%), Positives = 54/102 (52%)
Frame = +2
Query: 2 GMDVIATREATKFAIDYCTSGKGPLLIEMETYRYSGHSMSDPGTSYRTRDEVQEVRQTRD 181
G + + E A+D P LI ++ R S HS SD YR+ ++ ++ +D
Sbjct: 214 GGNYTSLTETFSHAVDQARQHSVPALILIDVVRLSSHSNSDNQEKYRSALDL-KLSMDKD 272
Query: 182 PITSFKEKVINNQLVTPDQLKEIDAKVRKETDEASKQAKADP 307
P+ +++ IN ++P +++EI A+ ++E ++ + A+A P
Sbjct: 273 PLILLEKEAINVFGLSPFEIEEIKAEAQEEVRKSCEIAEALP 314
>UniRef50_Q83DQ6 Cluster: Dehydrogenase, E1 component, alpha
subunit; n=3; Coxiella burnetii|Rep: Dehydrogenase, E1
component, alpha subunit - Coxiella burnetii
Length = 368
Score = 45.2 bits (102), Expect = 0.001
Identities = 27/97 (27%), Positives = 49/97 (50%)
Frame = +2
Query: 2 GMDVIATREATKFAIDYCTSGKGPLLIEMETYRYSGHSMSDPGTSYRTRDEVQEVRQTRD 181
G DVIA R A A++ G GP LIE +YR H+ +D T Y ++E +V ++
Sbjct: 229 GNDVIAVRYAVSKALEKARDGGGPTLIEALSYRLCDHTTADDATRYIPQEE-WKVAWQKE 287
Query: 182 PITSFKEKVINNQLVTPDQLKEIDAKVRKETDEASKQ 292
PI + + L + ++ + ++ +E D+ ++
Sbjct: 288 PIARLGYYLESQGLWSREKEAVLQKELAQEVDQVVEE 324
>UniRef50_Q8SQM8 Cluster: PYRUVATE DEHYDROGENASE E1 COMPONENT ALPHA
SUBUNIT; n=1; Encephalitozoon cuniculi|Rep: PYRUVATE
DEHYDROGENASE E1 COMPONENT ALPHA SUBUNIT -
Encephalitozoon cuniculi
Length = 349
Score = 45.2 bits (102), Expect = 0.001
Identities = 26/111 (23%), Positives = 54/111 (48%)
Frame = +2
Query: 8 DVIATREATKFAIDYCTSGKGPLLIEMETYRYSGHSMSDPGTSYRTRDEVQEVRQTRDPI 187
++ K+A Y GP++++++TYR+ HS +D SYR+R+EV + + RD +
Sbjct: 241 NIFGLMSVLKYARKYSVEN-GPIIVQIDTYRFCTHSAADERESYRSREEV-DAEKKRDCM 298
Query: 188 TSFKEKVINNQLVTPDQLKEIDAKVRKETDEASKQAKADPEIPIEELSGDI 340
+++ + ++L + + + E + A+ +EL DI
Sbjct: 299 EDVGRRLL--AFYSEEELDALRSSILAEVERDVDAARKSRPTEEDELCRDI 347
>UniRef50_Q8PQ82 Cluster: Pyruvate dehydrogenase E1 alpha subunit;
n=7; Xanthomonadaceae|Rep: Pyruvate dehydrogenase E1
alpha subunit - Xanthomonas axonopodis pv. citri
Length = 362
Score = 44.4 bits (100), Expect = 0.002
Identities = 31/114 (27%), Positives = 49/114 (42%)
Frame = +2
Query: 2 GMDVIATREATKFAIDYCTSGKGPLLIEMETYRYSGHSMSDPGTSYRTRDEVQEVRQTRD 181
G D++A EA + A +G+G +IE TYR S H+ +D YR +EV++ R+
Sbjct: 228 GNDLVAVLEAMRQARVRALAGEGGTVIEFLTYRLSDHTTADDARRYRGEEEVKQ-GWARE 286
Query: 182 PITSFKEKVINNQLVTPDQLKEIDAKVRKETDEASKQAKADPEIPIEELSGDIY 343
P+ + + L Q A DE P P+E + +Y
Sbjct: 287 PLLRLRRYLTAQGLWDEAQEDAWKADCSARVDEEVNAYLNTPVQPVEAMFDYLY 340
>UniRef50_Q5LVW0 Cluster: Dehydrogenase/transketolase family
protein; n=23; Proteobacteria|Rep:
Dehydrogenase/transketolase family protein -
Silicibacter pomeroyi
Length = 740
Score = 44.4 bits (100), Expect = 0.002
Identities = 25/104 (24%), Positives = 47/104 (45%)
Frame = +2
Query: 2 GMDVIATREATKFAIDYCTSGKGPLLIEMETYRYSGHSMSDPGTSYRTRDEVQEVRQTRD 181
G+D+ T + A DY + + P + ++T R GH+ +D T+Y TR EV E + D
Sbjct: 259 GLDIYETYAVAQEAADYVRNRRKPAFLHLKTVRLYGHAGADVPTTYLTRAEV-EAEEAMD 317
Query: 182 PITSFKEKVINNQLVTPDQLKEIDAKVRKETDEASKQAKADPEI 313
P+ + + + ++ I + D + +A P +
Sbjct: 318 PLLHSVRLLAEDGALASEEALAIYEQTCARIDRIAVEAATRPHL 361
>UniRef50_A0M1U4 Cluster: 2-oxoisovalerate dehydrogenase E1
component subunits alpha and beta; n=18;
Bacteroidetes|Rep: 2-oxoisovalerate dehydrogenase E1
component subunits alpha and beta - Gramella forsetii
(strain KT0803)
Length = 685
Score = 44.0 bits (99), Expect = 0.003
Identities = 27/97 (27%), Positives = 52/97 (53%), Gaps = 1/97 (1%)
Frame = +2
Query: 71 PLLIEMETYRYSGHSMSDPGTSYRTRDEVQEVRQTRDPITSFKEKVINNQLVTPDQLKEI 250
P+L+E +T+R GH + GT Y ++ + E +Q +DP+ +F+E +I ++T D ++
Sbjct: 261 PVLVEFKTFRMRGHEEAS-GTKYVPQELMDEWQQ-KDPVLNFEEYLIAKNILTNDLKEKF 318
Query: 251 DAKVRKETDEASKQAKADPEIPIEELSG-DIYYSNLE 358
++ E D+ + A ++ I + D Y N E
Sbjct: 319 RTEILAEIDKNLQLAFSEDIIVSDATKELDDVYENFE 355
>UniRef50_Q1KSF2 Cluster: Mitochondrial branched-chain alpha-keto
acid dehydrogenase E1; n=1; Toxoplasma gondii|Rep:
Mitochondrial branched-chain alpha-keto acid
dehydrogenase E1 - Toxoplasma gondii
Length = 463
Score = 44.0 bits (99), Expect = 0.003
Identities = 30/89 (33%), Positives = 43/89 (48%), Gaps = 1/89 (1%)
Frame = +2
Query: 2 GMDVIATREATKFAIDYCTSGKGPLLIEMETYRYSGHSMSDPGTSYRTRDEVQEVRQTR- 178
G D+ A+ ATK A + S + P+LIE TYR HS SD YR E++ Q+
Sbjct: 314 GNDLFASLLATKKAREIIVSQRQPVLIEFMTYRVGHHSTSDDSFQYRPSGELEAWGQSGI 373
Query: 179 DPITSFKEKVINNQLVTPDQLKEIDAKVR 265
PI + + N L + Q +E+ R
Sbjct: 374 HPIARVRRYLDNLNLWSDKQDEELRKDAR 402
>UniRef50_Q0RLC2 Cluster: Pyruvate dehydrogenase E1 component, alpha
subunit; n=2; Bacteria|Rep: Pyruvate dehydrogenase E1
component, alpha subunit - Frankia alni (strain ACN14a)
Length = 342
Score = 43.6 bits (98), Expect = 0.004
Identities = 33/115 (28%), Positives = 55/115 (47%), Gaps = 1/115 (0%)
Frame = +2
Query: 2 GMDVIATREATKFAIDYCTSGKGPLLIEMETYRYSGHSMSDPGTSYRTRDEVQEVRQTRD 181
G D I A AI+ +G GP L+E T+R+ GH M D Y +E++ D
Sbjct: 223 GNDPIELYNAAGAAIERARTGGGPTLLEAMTFRFCGHIMGDQQV-YMPPEELR-AAIAAD 280
Query: 182 PITSFKEKVINNQLVTPDQLKEIDAKVRKETDEASKQAKADPEIP-IEELSGDIY 343
P+ F+ ++ + V D+L ++ E +A + A+ E+P L+ D+Y
Sbjct: 281 PLVRFRAQLAAD--VGEDELAAVERAAADEVADAWEFART-AELPAASALTTDVY 332
>UniRef50_Q5VGY4 Cluster: Pyruvate dehydrogenase alpha subunit; n=6;
Plasmodium|Rep: Pyruvate dehydrogenase alpha subunit -
Plasmodium falciparum
Length = 608
Score = 42.7 bits (96), Expect = 0.006
Identities = 32/104 (30%), Positives = 49/104 (47%), Gaps = 1/104 (0%)
Frame = +2
Query: 2 GMDVIATREATKFAIDYCTSG-KGPLLIEMETYRYSGHSMSDPGTSYRTRDEVQEVRQTR 178
G DV+ + K I + GP++IE TYR GHS++DP R ++E ++ R
Sbjct: 429 GNDVLTIYKLAKKKIQQIRNRTSGPIIIEAITYRAKGHSLADP-DELRIKEEKTSWKK-R 486
Query: 179 DPITSFKEKVINNQLVTPDQLKEIDAKVRKETDEASKQAKADPE 310
DPI + LV ++ V+K T +QA+ D E
Sbjct: 487 DPILFLSSYMKKYNLVQESYFEQ----VKKNTQTLLQQAELDAE 526
>UniRef50_Q023C4 Cluster: Pyruvate dehydrogenase; n=1; Solibacter
usitatus Ellin6076|Rep: Pyruvate dehydrogenase -
Solibacter usitatus (strain Ellin6076)
Length = 397
Score = 42.3 bits (95), Expect = 0.008
Identities = 28/110 (25%), Positives = 52/110 (47%), Gaps = 2/110 (1%)
Frame = +2
Query: 197 KEKVINNQLVTPDQLKEIDAKVRKETDEASKQAKADPEIPIEELSGDIYYSNLEP-FIRG 373
K+ +I N+++TPD+++ A ++ E D+A+ +A + P+ L IY P +R
Sbjct: 6 KDTLIRNRVLTPDEVEAFRASIKSEVDQAAAEADSHPQPATSNLLAHIYSERTAPAIVRP 65
Query: 374 THPGAQLQHIQVAARK*TVSQFKKEKHKSILWGRSSVTLNTN-*GVRRGL 520
T+ A+ + A + + + K ++WG GV RGL
Sbjct: 66 TYL-AEKPVTMIDAINHGLREEMERNPKIVMWGEDIADPKGGVFGVTRGL 114
>UniRef50_Q319T4 Cluster: Pyruvate dehydrogenase; n=1;
Prochlorococcus marinus str. MIT 9312|Rep: Pyruvate
dehydrogenase - Prochlorococcus marinus (strain MIT
9312)
Length = 347
Score = 41.9 bits (94), Expect = 0.011
Identities = 31/121 (25%), Positives = 56/121 (46%), Gaps = 4/121 (3%)
Frame = +2
Query: 2 GMDVIATREATKFAIDYCTSGKGPLLIEMETYRYSGH----SMSDPGTSYRTRDEVQEVR 169
G ++ + + K I C G+GP IE TYR+ GH D G + R+ D+++ +
Sbjct: 227 GNNLTSICKTGKEFIRRCRDGEGPFFIEALTYRWFGHVDWREDIDVGIN-RSADDLKYWK 285
Query: 170 QTRDPITSFKEKVINNQLVTPDQLKEIDAKVRKETDEASKQAKADPEIPIEELSGDIYYS 349
+ RDPI K+ ++ + L ++ ++K+ D A A + E ++ S
Sbjct: 286 K-RDPILRLKKSLLKENYFGENHLINLEKDIQKDIDNAWVDALGESSPEWNESLDYVFKS 344
Query: 350 N 352
N
Sbjct: 345 N 345
>UniRef50_A3TUC4 Cluster: TPP-dependent acetoin dehydrogenase
complex, E1 component, alpha subunit; n=1; Oceanicola
batsensis HTCC2597|Rep: TPP-dependent acetoin
dehydrogenase complex, E1 component, alpha subunit -
Oceanicola batsensis HTCC2597
Length = 86
Score = 41.9 bits (94), Expect = 0.011
Identities = 24/76 (31%), Positives = 42/76 (55%), Gaps = 2/76 (2%)
Frame = +2
Query: 86 METYRYSGHSMSDPGTSYRTRDEVQEVRQTRDPITSFKEKVINNQLVTPDQLKEIDAKVR 265
METYR +GH M D YR E + + +DPI + + +++ + + ++L I+A+
Sbjct: 1 METYRLAGHFMGD-AEGYRPEGEKDGLFE-KDPIPAMRARLLKDGAASEEELAAIEAEAE 58
Query: 266 KETDEASKQAK--ADP 307
++A K A+ ADP
Sbjct: 59 ARVEKAIKFARDSADP 74
>UniRef50_A0HHH5 Cluster: Dehydrogenase, E1 component; n=2;
Bacteria|Rep: Dehydrogenase, E1 component - Comamonas
testosteroni KF-1
Length = 327
Score = 41.5 bits (93), Expect = 0.015
Identities = 23/69 (33%), Positives = 36/69 (52%)
Frame = +2
Query: 2 GMDVIATREATKFAIDYCTSGKGPLLIEMETYRYSGHSMSDPGTSYRTRDEVQEVRQTRD 181
G D++ R+ + +G GP+LIEM T R GH + D SYRT E+ E + +
Sbjct: 215 GNDILGVRQCMEHFGQKVRNGHGPVLIEMMTQRLVGHYIGDM-QSYRTAREIAEAK-LHE 272
Query: 182 PITSFKEKV 208
PI +++
Sbjct: 273 PIVRLGQRL 281
>UniRef50_Q9HN77 Cluster: Pyruvate dehydrogenase alpha subunit; n=8;
Halobacteriaceae|Rep: Pyruvate dehydrogenase alpha
subunit - Halobacterium salinarium (Halobacterium
halobium)
Length = 419
Score = 41.1 bits (92), Expect = 0.019
Identities = 28/118 (23%), Positives = 51/118 (43%), Gaps = 4/118 (3%)
Frame = +2
Query: 2 GMDVIATREATKFAIDYCTSGKG----PLLIEMETYRYSGHSMSDPGTSYRTRDEVQEVR 169
GMD +A + AI+ P LIE YR+ H+ +D + YR EV E
Sbjct: 274 GMDPLAVYQVAHDAIEKAKDPDEDEMRPTLIEAVQYRFGAHTTADDPSVYREESEV-EAW 332
Query: 170 QTRDPITSFKEKVINNQLVTPDQLKEIDAKVRKETDEASKQAKADPEIPIEELSGDIY 343
+ +DPI + ++ + ++ I+A + +A + A+ P + ++Y
Sbjct: 333 KDKDPIPRLETFLVETDRLDDAAIESIEADIEDAVADAIEAAEETPRPDPASMFENVY 390
>UniRef50_A5V540 Cluster: Dehydrogenase, E1 component; n=3;
Proteobacteria|Rep: Dehydrogenase, E1 component -
Sphingomonas wittichii RW1
Length = 334
Score = 40.7 bits (91), Expect = 0.025
Identities = 29/114 (25%), Positives = 53/114 (46%)
Frame = +2
Query: 2 GMDVIATREATKFAIDYCTSGKGPLLIEMETYRYSGHSMSDPGTSYRTRDEVQEVRQTRD 181
G DV E +D +GP ++E T R GH D YR +D+ V D
Sbjct: 221 GSDVETVAELAADVVDRVRRDRGPAVLEFATTRIRGHYEGD-AQRYR-QDKAPPV----D 274
Query: 182 PITSFKEKVINNQLVTPDQLKEIDAKVRKETDEASKQAKADPEIPIEELSGDIY 343
P+ + + ++ + V +++ I+A +R E A + A+ P+ +E + ++Y
Sbjct: 275 PLLVARAR-LDERGVPAAEVEAIEADIRAEVRRAVEAARLSPDPTLESAAEEVY 327
>UniRef50_Q28MR4 Cluster: Dehydrogenase E1 component; n=8;
Bacteria|Rep: Dehydrogenase E1 component - Jannaschia
sp. (strain CCS1)
Length = 675
Score = 40.3 bits (90), Expect = 0.034
Identities = 34/107 (31%), Positives = 51/107 (47%)
Frame = +2
Query: 2 GMDVIATREATKFAIDYCTSGKGPLLIEMETYRYSGHSMSDPGTSYRTRDEVQEVRQTRD 181
G D+ A A A +G GP LIE TYR+ HSM +YR+ E +E +++D
Sbjct: 222 GNDLPAVHMAVSRAALRARAGDGPTLIEALTYRWDDHSMRANLPAYRSEAE-EEAWKSQD 280
Query: 182 PITSFKEKVINNQLVTPDQLKEIDAKVRKETDEASKQAKADPEIPIE 322
PI + + +L E+DA ++ +A+AD E IE
Sbjct: 281 PIVRLEADM--------SKLGELDAASYAALND---EAEADVEAAIE 316
>UniRef50_A1SN84 Cluster: Pyruvate dehydrogenase; n=12;
Bacteria|Rep: Pyruvate dehydrogenase - Nocardioides sp.
(strain BAA-499 / JS614)
Length = 344
Score = 40.3 bits (90), Expect = 0.034
Identities = 27/102 (26%), Positives = 50/102 (49%)
Frame = +2
Query: 2 GMDVIATREATKFAIDYCTSGKGPLLIEMETYRYSGHSMSDPGTSYRTRDEVQEVRQTRD 181
G DV +A + A+ +G+GP LIE+ T R GH D YR ++++ + D
Sbjct: 234 GNDVEGVYDAARRAVARARAGEGPSLIEVHTLRLWGHFEGD-AQGYRL--DLEDA-PSHD 289
Query: 182 PITSFKEKVINNQLVTPDQLKEIDAKVRKETDEASKQAKADP 307
PI ++ ++ ++ + + I + + T++A AK P
Sbjct: 290 PIPRYETRLREAGVLDDETVTRIRSAASERTEDAIAFAKNSP 331
>UniRef50_Q95VS6 Cluster: Pyruvate dehydrogenase E1 alpha subunit;
n=2; Antonospora locustae|Rep: Pyruvate dehydrogenase E1
alpha subunit - Antonospora locustae (Nosema locustae)
Length = 342
Score = 39.9 bits (89), Expect = 0.044
Identities = 29/92 (31%), Positives = 45/92 (48%)
Frame = +2
Query: 65 KGPLLIEMETYRYSGHSMSDPGTSYRTRDEVQEVRQTRDPITSFKEKVINNQLVTPDQLK 244
KGPL+++++TYR GHS +D G YR EV+ R+ R+ + + ++ Q + +
Sbjct: 252 KGPLIVQIDTYRLCGHSTTD-GIVYRDETEVRRERE-RNALGHTESALV--QRFGAEHIA 307
Query: 245 EIDAKVRKETDEASKQAKADPEIPIEELSGDI 340
I A VR A A E EL D+
Sbjct: 308 AIKADVRSHVAHEVDVALAMLEPEPTELFRDV 339
>UniRef50_Q0LRY7 Cluster: Dehydrogenase, E1 component:Transketolase,
central region:Transketolase-like; n=3; cellular
organisms|Rep: Dehydrogenase, E1
component:Transketolase, central
region:Transketolase-like - Caulobacter sp. K31
Length = 680
Score = 39.5 bits (88), Expect = 0.059
Identities = 26/96 (27%), Positives = 47/96 (48%)
Frame = +2
Query: 2 GMDVIATREATKFAIDYCTSGKGPLLIEMETYRYSGHSMSDPGTSYRTRDEVQEVRQTRD 181
G D + R++ A + +G GP LIE R GH D YR++ + E RD
Sbjct: 220 GTDPVVVRDSFAMAAAHARAGNGPSLIECTVPRLWGHYNRDI-EHYRSKADRAEA-TARD 277
Query: 182 PITSFKEKVINNQLVTPDQLKEIDAKVRKETDEASK 289
P+ ++ + ++T D++ A +RK ++A++
Sbjct: 278 PLVLLAARLQQDGVMTDDEV----AAIRKSQEDAAR 309
>UniRef50_Q93N50 Cluster: Pyruvate dehydrogenase alpha subunit; n=4;
Proteobacteria|Rep: Pyruvate dehydrogenase alpha subunit
- Coxiella burnetii
Length = 341
Score = 39.1 bits (87), Expect = 0.078
Identities = 22/87 (25%), Positives = 47/87 (54%), Gaps = 1/87 (1%)
Frame = +2
Query: 68 GPLLIEMETYRYSGHSMSDPGT-SYRTRDEVQEVRQTRDPITSFKEKVINNQLVTPDQLK 244
G +E +TYR+ H + T + R++ E RDP++ + +++ + V+P+++
Sbjct: 229 GVWFLEFQTYRFKVHCGPEEETFTDRSKTEFDHWL-ARDPLSLLQSQLLTAKTVSPEEID 287
Query: 245 EIDAKVRKETDEASKQAKADPEIPIEE 325
+ +++ E DEA A++ P P E+
Sbjct: 288 KWRHEIQNEIDEAFTFAESSPYPPPED 314
>UniRef50_Q4SEP7 Cluster: Chromosome 3 SCAF14614, whole genome
shotgun sequence; n=1; Tetraodon nigroviridis|Rep:
Chromosome 3 SCAF14614, whole genome shotgun sequence -
Tetraodon nigroviridis (Green puffer)
Length = 773
Score = 38.7 bits (86), Expect = 0.10
Identities = 32/98 (32%), Positives = 44/98 (44%), Gaps = 5/98 (5%)
Frame = +1
Query: 103 LWAFDVRPGNVVPHEGRGPGGAPDQGPDHLLQGEGHQQPTRHSRSVKGNRRESTQGNRRG 282
L +F + G P GRG GGA +G QG ++ H +++G RE+ +G R
Sbjct: 237 LKSFALMLGQDRPRPGRGAGGAAPEGAGDGGQG---RRAAPHGGALQGPGREAGEGGRPE 293
Query: 283 FET----G*GRP*DPNRGALRGHILLEP-GTFHPRHPP 381
E G P DP G G + EP G P+ PP
Sbjct: 294 PEPEGGGGQPEPPDPGPGEAGGRLRQEPAGVRLPQEPP 331
>UniRef50_Q6L1L8 Cluster: Pyruvate dehydrogenase E1 component alpha
subunit; n=2; Thermoplasmatales|Rep: Pyruvate
dehydrogenase E1 component alpha subunit - Picrophilus
torridus
Length = 333
Score = 37.1 bits (82), Expect = 0.31
Identities = 28/107 (26%), Positives = 48/107 (44%), Gaps = 4/107 (3%)
Frame = +2
Query: 2 GMDVIATREATKFAIDYCTSGKGPLLIEMETYRYSGHSMSDPGTSYRTRDEVQEVRQTRD 181
G + I A + AI K PLLI+ TYR H+ +D YR + + E D
Sbjct: 207 GNNFIEAYHAIRNAIKDVEKNKMPLLIDAVTYRMGPHTTADDPNKYR-KTIINE-GDPLD 264
Query: 182 PITSFKEKVINNQLVTPDQL----KEIDAKVRKETDEASKQAKADPE 310
P++ ++ + +++ +++ EI+ V KE + K K E
Sbjct: 265 PLSIIEDDIKKMKILNDEEISNIKNEINNMVSKEVERYEKMNKPGKE 311
>UniRef50_A0BCX8 Cluster: Chromosome undetermined scaffold_10, whole
genome shotgun sequence; n=1; Paramecium
tetraurelia|Rep: Chromosome undetermined scaffold_10,
whole genome shotgun sequence - Paramecium tetraurelia
Length = 893
Score = 36.7 bits (81), Expect = 0.41
Identities = 27/99 (27%), Positives = 47/99 (47%)
Frame = +2
Query: 2 GMDVIATREATKFAIDYCTSGKGPLLIEMETYRYSGHSMSDPGTSYRTRDEVQEVRQTRD 181
G DV + +KFA++Y K +LI++ TYR GH+ D S+ + ++VR+ +
Sbjct: 371 GEDVETLHKVSKFAVEYRQKFKKDILIDIVTYRKYGHNEVDE-PSFTQPNMYEKVRKAKS 429
Query: 182 PITSFKEKVINNQLVTPDQLKEIDAKVRKETDEASKQAK 298
+ N Q + ++I KV D ++AK
Sbjct: 430 LPVKY-----NQQHFRQEDYEKIRQKVFAYLDSEYEKAK 463
>UniRef50_A7D3P2 Cluster: Pyruvate dehydrogenase; n=1; Halorubrum
lacusprofundi ATCC 49239|Rep: Pyruvate dehydrogenase -
Halorubrum lacusprofundi ATCC 49239
Length = 382
Score = 36.7 bits (81), Expect = 0.41
Identities = 37/134 (27%), Positives = 57/134 (42%), Gaps = 11/134 (8%)
Frame = +2
Query: 2 GMDVIATREATKFAIDYCTSGKG--------PLLIEMETYRYSGHSMSDPGTSYRTRDEV 157
GMD +A+ TK A D + P LIE YR+ H+ +D T+YR D V
Sbjct: 233 GMDPLASYAVTKEAADRARRNEDDSPVDAPRPALIEFLEYRFGAHTTADDPTAYRDPDAV 292
Query: 158 QEVRQTRDPITSFKEKVINNQLVTPDQLKEIDAKVRKETDEASKQAKADPEIPIEELSGD 337
R DP+ + + + D + A + +E DE A D +E D
Sbjct: 293 DPWR-ALDPLDRMEAFLRETGRIDDDGV----AAIHEEADEIVADA-IDFAESVEPDPAD 346
Query: 338 IY---YSNLEPFIR 370
++ Y++L P +R
Sbjct: 347 MFDHAYADLPPELR 360
>UniRef50_UPI0000E80F2F Cluster: PREDICTED: hypothetical protein;
n=1; Gallus gallus|Rep: PREDICTED: hypothetical protein
- Gallus gallus
Length = 211
Score = 36.3 bits (80), Expect = 0.55
Identities = 30/99 (30%), Positives = 42/99 (42%)
Frame = +1
Query: 121 RPGNVVPHEGRGPGGAPDQGPDHLLQGEGHQQPTRHSRSVKGNRRESTQGNRRGFETG*G 300
RPG + RG G P++GP +Q ++ R + + +RR+ G RR G G
Sbjct: 70 RPGGAALGQRRG-GAEPERGPRRGMQVGAERRSERGGAAAERSRRQRAAGGRRR-RRGSG 127
Query: 301 RP*DPNRGALRGHILLEPGTFHPRHPPRGAVAAHPGRCT 417
+P GA +P P RG A PGR T
Sbjct: 128 DA-EPRPGAA---ARWDPEPARPSPAARGRPRAGPGRAT 162
>UniRef50_Q4RFZ6 Cluster: Chromosome undetermined SCAF15108, whole
genome shotgun sequence; n=1; Tetraodon
nigroviridis|Rep: Chromosome undetermined SCAF15108,
whole genome shotgun sequence - Tetraodon nigroviridis
(Green puffer)
Length = 149
Score = 36.3 bits (80), Expect = 0.55
Identities = 36/102 (35%), Positives = 43/102 (42%), Gaps = 7/102 (6%)
Frame = +1
Query: 145 EGRGPGGAP--DQGPDHLLQGEGHQQPTRHSRSVKGNRRES-----TQGNRRGFETG*GR 303
+G G GGA QGP Q GH Q TRH RRE+ +G+ RG E G
Sbjct: 9 KGLGKGGAKRHPQGPPR--QHPGHHQ-TRHPPPGSARRREAHLRPDLRGDPRGAEGVPGE 65
Query: 304 P*DPNRGALRGHILLEPGTFHPRHPPRGAVAAHPGRCTQIDR 429
DP R L G E G H R HP R +++R
Sbjct: 66 R-DPRRRHLHGARQEEDGDGHGRGVRPEEAGPHPVRLRRLER 106
>UniRef50_Q4T4Q5 Cluster: Chromosome undetermined SCAF9565, whole
genome shotgun sequence; n=1; Tetraodon
nigroviridis|Rep: Chromosome undetermined SCAF9565,
whole genome shotgun sequence - Tetraodon nigroviridis
(Green puffer)
Length = 743
Score = 35.9 bits (79), Expect = 0.72
Identities = 20/54 (37%), Positives = 26/54 (48%)
Frame = +1
Query: 121 RPGNVVPHEGRGPGGAPDQGPDHLLQGEGHQQPTRHSRSVKGNRRESTQGNRRG 282
R G+V GRGPGG + PD L + + R + G RR+ T G R G
Sbjct: 544 RQGDVHHQAGRGPGGGWSRPPDRLRHHQSWLR-VRGDQLACGGRRQPTHGQREG 596
>UniRef50_Q7VR91 Cluster: 2-oxoglutarate dehydrogenase E1 component;
n=2; Candidatus Blochmannia|Rep: 2-oxoglutarate
dehydrogenase E1 component - Blochmannia floridanus
Length = 970
Score = 35.9 bits (79), Expect = 0.72
Identities = 22/91 (24%), Positives = 45/91 (49%), Gaps = 1/91 (1%)
Frame = +2
Query: 8 DVIATREATKFAIDYCTSGKGPLLIEMETYRYSGHSMSDPGTSYRTRDEV-QEVRQTRDP 184
DV A T+FA+++ K ++I++ YR GH+ +D + T+ + Q++R
Sbjct: 453 DVHAVIFVTRFALNFRNKFKHDIVIDLVCYRRHGHNETD--EPHVTQPMMYQKIRNHPTV 510
Query: 185 ITSFKEKVINNQLVTPDQLKEIDAKVRKETD 277
+ + +K+I ++ D +K R + D
Sbjct: 511 LELYAQKLIQKNIINVDDIKNESCLYRSKLD 541
>UniRef50_UPI0000EBDC73 Cluster: PREDICTED: hypothetical protein
LOC515229; n=1; Bos taurus|Rep: PREDICTED: hypothetical
protein LOC515229 - Bos taurus
Length = 461
Score = 35.1 bits (77), Expect = 1.3
Identities = 35/100 (35%), Positives = 43/100 (43%), Gaps = 9/100 (9%)
Frame = +1
Query: 154 GPGGAPDQGPDHLLQGEGHQQPTR-HSRSVKGNRRESTQGNRR--GFETG--*GRP*DPN 318
GP GA QGPD L Q H+QP R +++G R + G R G G GR P
Sbjct: 260 GPAGAAPQGPDCLRQLASHRQPPRVFDPAMRGLRXAAAGGAARVPGAHRGRAAGRGRSPG 319
Query: 319 RGALRGHILLEPGTFHPRH----PPRGAVAAHPGRCTQID 426
R L G + L + P P G AA PG + D
Sbjct: 320 RRPLAG-LALGGAGWEPLAAGLVPGXGCPAAGPGXAGRWD 358
>UniRef50_A5NZK1 Cluster: Methyl-accepting chemotaxis sensory
transducer; n=5; Proteobacteria|Rep: Methyl-accepting
chemotaxis sensory transducer - Methylobacterium sp.
4-46
Length = 706
Score = 35.1 bits (77), Expect = 1.3
Identities = 34/99 (34%), Positives = 39/99 (39%), Gaps = 2/99 (2%)
Frame = +1
Query: 121 RPGNVVPHEGRGPGGAPDQG--PDHLLQGEGHQQPTRHSRSVKGNRRESTQGNRRGFETG 294
RPG P G GG +G P G + R +R G+R + RRG
Sbjct: 47 RPG---PAAAPGRGGRAPRGAAPGRATAGPAGRAGARRARRAPGSRPRPARAGRRG---- 99
Query: 295 *GRP*DPNRGALRGHILLEPGTFHPRHPPRGAVAAHPGR 411
P P RG RG L PG P PR AAHP R
Sbjct: 100 ---P-RPRRGGRRG-ALRAPGKLRPPR-PRRPPAAHPRR 132
>UniRef50_Q6YXU3 Cluster: Putative uncharacterized protein
P0427G12.5; n=1; Oryza sativa (japonica
cultivar-group)|Rep: Putative uncharacterized protein
P0427G12.5 - Oryza sativa subsp. japonica (Rice)
Length = 159
Score = 35.1 bits (77), Expect = 1.3
Identities = 17/53 (32%), Positives = 26/53 (49%)
Frame = +1
Query: 121 RPGNVVPHEGRGPGGAPDQGPDHLLQGEGHQQPTRHSRSVKGNRRESTQGNRR 279
R G+ +G G GG D+ +H G+GH+Q R R + ++ Q RR
Sbjct: 19 RRGSASGGDGLGVGGQQDEEEEHGEDGDGHEQQHRRRRRQRRQQQRQHQQRRR 71
>UniRef50_A7EFP6 Cluster: Predicted protein; n=1; Sclerotinia
sclerotiorum 1980|Rep: Predicted protein - Sclerotinia
sclerotiorum 1980
Length = 618
Score = 35.1 bits (77), Expect = 1.3
Identities = 23/79 (29%), Positives = 40/79 (50%), Gaps = 1/79 (1%)
Frame = +2
Query: 146 RDEVQEVRQTRDPITSFKEKVINNQLVTPDQLKEIDAKVRKETDEASKQAKADPEIP-IE 322
R ++ + R+T+ I S KEK N+ L D+ E D +TD SK+ +A+ + P +
Sbjct: 400 RTDLPKRRETKGAILSTKEKQTNSPLPEYDEADEYDKHQSHKTDR-SKRRRANAKKPHLP 458
Query: 323 ELSGDIYYSNLEPFIRGTH 379
+ + ++ Y RG H
Sbjct: 459 QRAREVTYPTTRTSGRGNH 477
>UniRef50_UPI00015C4945 Cluster: hypothetical protein CCC13826_0953;
n=1; Campylobacter concisus 13826|Rep: hypothetical
protein CCC13826_0953 - Campylobacter concisus 13826
Length = 542
Score = 34.7 bits (76), Expect = 1.7
Identities = 21/78 (26%), Positives = 44/78 (56%), Gaps = 2/78 (2%)
Frame = +2
Query: 152 EVQEVRQTRDPITSFKEKVINNQLVTPDQLKEIDAKVRKETDEAS--KQAKADPEIPIEE 325
E++ + QT+D + +KEK+I+ + + P +L D K + + D + K+ A EI E
Sbjct: 185 ELKPISQTKDVKSLYKEKIISGE-IDPSELSFEDFKEQLKPDPKALYKEKIASGEIDPTE 243
Query: 326 LSGDIYYSNLEPFIRGTH 379
+S + + +L+P ++ +
Sbjct: 244 ISFEEFKQSLKPDLKALY 261
>UniRef50_A5U0N1 Cluster: Dehydrogenase E1 component; n=7;
Mycobacterium tuberculosis complex|Rep: Dehydrogenase E1
component - Mycobacterium tuberculosis (strain ATCC
25177 / H37Ra)
Length = 334
Score = 34.7 bits (76), Expect = 1.7
Identities = 30/100 (30%), Positives = 47/100 (47%)
Frame = +2
Query: 2 GMDVIATREATKFAIDYCTSGKGPLLIEMETYRYSGHSMSDPGTSYRTRDEVQEVRQTRD 181
G DV A R+ A+ +G GP L++ TYR + S SD G YR ++ Q D
Sbjct: 215 GNDVEAVRDCVANAVVRARAGGGPTLVQAITYRTTDFSGSDRG-GYR---DLAGSEQFLD 270
Query: 182 PITSFKEKVINNQLVTPDQLKEIDAKVRKETDEASKQAKA 301
P+ + ++I T +L E + ++ +A AKA
Sbjct: 271 PLIFARRRLIAAG-TTRGRLDEQERAACQQVADAVAFAKA 309
>UniRef50_Q4N6Q9 Cluster: Putative uncharacterized protein; n=2;
Theileria|Rep: Putative uncharacterized protein -
Theileria parva
Length = 874
Score = 34.7 bits (76), Expect = 1.7
Identities = 23/90 (25%), Positives = 45/90 (50%), Gaps = 1/90 (1%)
Frame = +2
Query: 65 KGPLLIEMETYRYSGHSMSDPGTSYRTRDEVQEVRQTRDPITSFKEKVINNQLVTPDQLK 244
K P L+ E Y YS ++ S+P + RD + T + ++ + + QL +QL+
Sbjct: 219 KTPELLS-EPYEYSEYNKSNPPEEFEERDSYDQ--DTSEQLSEPVSEPVYEQL--SEQLQ 273
Query: 245 E-IDAKVRKETDEASKQAKADPEIPIEELS 331
E + ++ K+ E + +PE+P +L+
Sbjct: 274 EQLSGQISKQLSETVSEPVPEPEVPEPQLT 303
>UniRef50_Q16GX6 Cluster: Pickpocket; n=1; Aedes aegypti|Rep:
Pickpocket - Aedes aegypti (Yellowfever mosquito)
Length = 497
Score = 34.7 bits (76), Expect = 1.7
Identities = 16/43 (37%), Positives = 22/43 (51%)
Frame = -3
Query: 483 TLERPQRIDLCFSFLNCETVYLRAATWMCCNCAPGWVPRMKGS 355
T ER R ++ +NCET L T+ C C W+P KG+
Sbjct: 297 THERYLRFFKIYNKINCETECLTNYTYHLCGCVQFWMPHPKGA 339
>UniRef50_Q04632 Cluster: Conserved oligomeric Golgi complex subunit
8; n=2; Saccharomyces cerevisiae|Rep: Conserved
oligomeric Golgi complex subunit 8 - Saccharomyces
cerevisiae (Baker's yeast)
Length = 607
Score = 34.7 bits (76), Expect = 1.7
Identities = 22/67 (32%), Positives = 35/67 (52%), Gaps = 1/67 (1%)
Frame = +2
Query: 131 TSYRTRDEVQEVRQTRDPITSFKEKVINNQLVTPDQ-LKEIDAKVRKETDEASKQAKADP 307
T + E +E T+D +E+ IN VTP++ K ID K KE +E +K + P
Sbjct: 445 TEDKAEKEKEEEVNTKDNKAEKEEEEINKVEVTPEEPSKSIDNKAEKEEEEINK-VEVTP 503
Query: 308 EIPIEEL 328
E P +++
Sbjct: 504 EEPSKKI 510
>UniRef50_UPI0000D9E76F Cluster: PREDICTED: hypothetical protein;
n=1; Macaca mulatta|Rep: PREDICTED: hypothetical protein
- Macaca mulatta
Length = 414
Score = 34.3 bits (75), Expect = 2.2
Identities = 36/100 (36%), Positives = 42/100 (42%), Gaps = 5/100 (5%)
Frame = +1
Query: 124 PGNVVPHEGRGPGGAPDQGPDHLLQGE--GHQQP-TRHSRSVKGNRR--ESTQGNRRGFE 288
PG P GR G P G H GE GH Q T H R +G + T G RRG
Sbjct: 171 PGPHTPPRGRA-GATP--GSPHPTTGERRGHSQVRTPHHRGAQGPPQVPTPTTGERRGHP 227
Query: 289 TG*GRP*DPNRGALRGHILLEPGTFHPRHPPRGAVAAHPG 408
+ P+ G +G PG P PPRG+ A PG
Sbjct: 228 ----QVPTPHHGGAQGP---PPG---PHTPPRGSAGATPG 257
>UniRef50_Q748I3 Cluster: Dehydrogenase, E1 component, alpha and
beta subunits; n=1; Geobacter sulfurreducens|Rep:
Dehydrogenase, E1 component, alpha and beta subunits -
Geobacter sulfurreducens
Length = 652
Score = 34.3 bits (75), Expect = 2.2
Identities = 25/93 (26%), Positives = 44/93 (47%), Gaps = 1/93 (1%)
Frame = +2
Query: 8 DVIATREATKFAIDYCTSGKGPLLIEMETYRYSGHSMSDPGTSYRTRDEVQEVRQT-RDP 184
D+ ++ K A+D + P+L+E++TYR HS D RD V+ R +D
Sbjct: 210 DIAGLLDSAKEAVDCVRKNQKPVLLEIDTYRLKAHSKGDD-----LRDPVEISRYAGQDS 264
Query: 185 ITSFKEKVINNQLVTPDQLKEIDAKVRKETDEA 283
I + E + T +Q ID+ +++ +A
Sbjct: 265 INALLESDVPRVAETVNQ---IDSNIQQAITKA 294
>UniRef50_Q0DJL7 Cluster: Os05g0263200 protein; n=13; Eukaryota|Rep:
Os05g0263200 protein - Oryza sativa subsp. japonica
(Rice)
Length = 1820
Score = 34.3 bits (75), Expect = 2.2
Identities = 20/52 (38%), Positives = 26/52 (50%), Gaps = 5/52 (9%)
Frame = +1
Query: 139 PHEGRGPGG-APDQGPDHLLQGEGH----QQPTRHSRSVKGNRRESTQGNRR 279
PH GRG GG D+G +H L+ G +QP R R +GNR + R
Sbjct: 85 PHPGRGNGGRGADRGREHGLEESGTDEEVEQPHRDDRRHRGNRGRNQPNEER 136
>UniRef50_A7PGG3 Cluster: Chromosome chr17 scaffold_16, whole genome
shotgun sequence; n=1; Vitis vinifera|Rep: Chromosome
chr17 scaffold_16, whole genome shotgun sequence - Vitis
vinifera (Grape)
Length = 300
Score = 34.3 bits (75), Expect = 2.2
Identities = 17/43 (39%), Positives = 26/43 (60%)
Frame = +2
Query: 65 KGPLLIEMETYRYSGHSMSDPGTSYRTRDEVQEVRQTRDPITS 193
K L+ MET SG+ SDPG S R ++Q+ R+ ++P +S
Sbjct: 41 KHDLVNPMETECNSGYGFSDPGVSPRVTADLQQNRENKNPNSS 83
>UniRef50_A7D571 Cluster: Putative uncharacterized protein
precursor; n=1; Halorubrum lacusprofundi ATCC 49239|Rep:
Putative uncharacterized protein precursor - Halorubrum
lacusprofundi ATCC 49239
Length = 462
Score = 33.9 bits (74), Expect = 2.9
Identities = 18/40 (45%), Positives = 22/40 (55%), Gaps = 4/40 (10%)
Frame = +1
Query: 124 PGNVVPHEGRGPGGAPDQG-PDHLLQG---EGHQQPTRHS 231
PGN H G+G G +QG PDH QG +G Q P H+
Sbjct: 364 PGNAPDHAGQGNGNDGEQGPPDHTGQGNGNDGEQGPPDHA 403
>UniRef50_Q88X31 Cluster: Putative uncharacterized protein lp_1417;
n=1; Lactobacillus plantarum|Rep: Putative
uncharacterized protein lp_1417 - Lactobacillus
plantarum
Length = 826
Score = 33.5 bits (73), Expect = 3.9
Identities = 21/82 (25%), Positives = 36/82 (43%)
Frame = +2
Query: 113 SMSDPGTSYRTRDEVQEVRQTRDPITSFKEKVINNQLVTPDQLKEIDAKVRKETDEASKQ 292
+MS P ++ R Q +Q RD + N L D L + + K+T A+ +
Sbjct: 536 TMSGPDFAFVQRQVQQLTQQVRDLTEQLQALATTNGLADVDALTQAVSDAEKQTANATSR 595
Query: 293 AKADPEIPIEELSGDIYYSNLE 358
+ ++ ELS Y++LE
Sbjct: 596 QQLQQQLSSAELSALKQYTSLE 617
>UniRef50_A4CGF1 Cluster: 2-oxoglutarate dehydrogenase, E1
component; n=16; cellular organisms|Rep: 2-oxoglutarate
dehydrogenase, E1 component - Robiginitalea biformata
HTCC2501
Length = 940
Score = 33.5 bits (73), Expect = 3.9
Identities = 19/110 (17%), Positives = 51/110 (46%)
Frame = +2
Query: 8 DVIATREATKFAIDYCTSGKGPLLIEMETYRYSGHSMSDPGTSYRTRDEVQEVRQTRDPI 187
D A A FA++Y + + +++ YR GH+ D + + + + ++P
Sbjct: 415 DAEAVVHAALFALEYRMKFRRDVFLDLLGYRKYGHNEGDE-PRFTQPKLYKAIAKHQNPR 473
Query: 188 TSFKEKVINNQLVTPDQLKEIDAKVRKETDEASKQAKADPEIPIEELSGD 337
+ E++++ ++ D +K+++ + + +E + +K + + I D
Sbjct: 474 DIYAERLMSEGVIDADFVKKLEEDYKAKLEEELRDSKKEDKTRITAFMAD 523
>UniRef50_A0GJ77 Cluster: Putative uncharacterized protein; n=4;
Burkholderia|Rep: Putative uncharacterized protein -
Burkholderia phytofirmans PsJN
Length = 1443
Score = 33.5 bits (73), Expect = 3.9
Identities = 22/48 (45%), Positives = 26/48 (54%), Gaps = 1/48 (2%)
Frame = -2
Query: 175 GLAHLLDLVPRAVRRSRVGHRMPRVSVRFHLNQ-KRPFTAGAVVNGEL 35
G A + D RA R +R RV VRFHL+Q R F A AVV +L
Sbjct: 1076 GCAFVADFAARAGRGARERRDRGRVIVRFHLHQGVREFVAAAVVLRQL 1123
>UniRef50_Q0UT66 Cluster: Predicted protein; n=1; Phaeosphaeria
nodorum|Rep: Predicted protein - Phaeosphaeria nodorum
(Septoria nodorum)
Length = 750
Score = 33.5 bits (73), Expect = 3.9
Identities = 19/64 (29%), Positives = 38/64 (59%), Gaps = 1/64 (1%)
Frame = +2
Query: 113 SMSDPGTSYRTRDEVQEVRQTRDPITSFKEKVINNQLVTPDQL-KEIDAKVRKETDEASK 289
S+SD T+ R+ + + T P+ + ++K+ ++ D++ KE + R+E +EA+K
Sbjct: 656 SVSD-STNGSNRNSLLIAKATVTPVDAVQQKLKGREVFNRDKMEKEAKERERREKEEAAK 714
Query: 290 QAKA 301
QA+A
Sbjct: 715 QARA 718
>UniRef50_UPI0000DD83A2 Cluster: PREDICTED: hypothetical protein;
n=1; Homo sapiens|Rep: PREDICTED: hypothetical protein -
Homo sapiens
Length = 257
Score = 33.1 bits (72), Expect = 5.1
Identities = 28/93 (30%), Positives = 37/93 (39%), Gaps = 2/93 (2%)
Frame = +1
Query: 124 PGNVVPHEGRGPGGA--PDQGPDHLLQGEGHQQPTRHSRSVKGNRRESTQGNRRGFETG* 297
PGN P RGPGGA Q H +G G + + +R +G + +G R
Sbjct: 99 PGNPTPRGHRGPGGAGRASQRTQHSPRG-GAGEKSAGARIDRGVPQAPRRGPRSPSRPPT 157
Query: 298 GRP*DPNRGALRGHILLEPGTFHPRHPPRGAVA 396
G P G+ + PG PPRG A
Sbjct: 158 GHPSRAEGGSHARGTAVRPGLAPGPAPPRGPSA 190
>UniRef50_Q7N3C2 Cluster: Similar to 3-methyl-2-oxobutanoate
dehydrogenase; n=1; Photorhabdus luminescens subsp.
laumondii|Rep: Similar to 3-methyl-2-oxobutanoate
dehydrogenase - Photorhabdus luminescens subsp.
laumondii
Length = 650
Score = 33.1 bits (72), Expect = 5.1
Identities = 24/93 (25%), Positives = 44/93 (47%), Gaps = 1/93 (1%)
Frame = +2
Query: 32 TKFAIDYCTSGKGPLLIEMETYRYSGHSMSDPGTSYRTRDEVQEVRQTRDPI-TSFKEKV 208
T+ I+Y + + P ++++TYR HS D R DE++ T DPI +E+
Sbjct: 207 TEELINYTRNQRHPAFLQIDTYRLKAHSKGD---DLRNIDEIEHF-NTIDPINVILRERA 262
Query: 209 INNQLVTPDQLKEIDAKVRKETDEASKQAKADP 307
+ + ++ +RK +KQA++ P
Sbjct: 263 AELETEVAGVQERVNDAIRK-----AKQARSSP 290
>UniRef50_A0QB51 Cluster: Dehydrogenase E1 component superfamily
protein; n=2; Mycobacterium avium|Rep: Dehydrogenase E1
component superfamily protein - Mycobacterium avium
(strain 104)
Length = 297
Score = 33.1 bits (72), Expect = 5.1
Identities = 17/49 (34%), Positives = 26/49 (53%)
Frame = +2
Query: 2 GMDVIATREATKFAIDYCTSGKGPLLIEMETYRYSGHSMSDPGTSYRTR 148
G DV+A ++ A+ + ++G GP L+E TYR + DP R R
Sbjct: 198 GRDVVAVGDSVGQAVRHASAGDGPSLVEAITYRTNHPVAIDPLVLARRR 246
>UniRef50_Q7QI36 Cluster: ENSANGP00000020537; n=1; Anopheles gambiae
str. PEST|Rep: ENSANGP00000020537 - Anopheles gambiae
str. PEST
Length = 507
Score = 33.1 bits (72), Expect = 5.1
Identities = 19/57 (33%), Positives = 25/57 (43%), Gaps = 1/57 (1%)
Frame = +1
Query: 139 PHEGRGPG-GAPDQGPDHLLQGEGHQQPTRHSRSVKGNRRESTQGNRRGFETG*GRP 306
P GRG G G+ QG G GH++P RH++ R +G GRP
Sbjct: 146 PSPGRGRGVGSSMQGERAANAGSGHRRPQRHAQGRGRGTRHGRNRRTAAGSSGAGRP 202
>UniRef50_Q6CLM5 Cluster: DNA polymerase epsilon subunit C; n=1;
Kluyveromyces lactis|Rep: DNA polymerase epsilon subunit
C - Kluyveromyces lactis (Yeast) (Candida sphaerica)
Length = 166
Score = 33.1 bits (72), Expect = 5.1
Identities = 23/84 (27%), Positives = 38/84 (45%), Gaps = 4/84 (4%)
Frame = +2
Query: 122 DPGTSYRTRDEVQ----EVRQTRDPITSFKEKVINNQLVTPDQLKEIDAKVRKETDEASK 289
D T+ R D+ Q V QT + + +E + +V P EID + E DEA++
Sbjct: 71 DLSTAIRNLDKFQFLSDVVPQTENLASLVRENKVRYTIVNPSP--EIDIESEDEVDEANE 128
Query: 290 QAKADPEIPIEELSGDIYYSNLEP 361
+PE+ E+ ++ EP
Sbjct: 129 PEVGEPEVDEAEVEAEVEAEAAEP 152
>UniRef50_UPI00015B4C52 Cluster: PREDICTED: similar to conserved
hypothetical protein; n=1; Nasonia vitripennis|Rep:
PREDICTED: similar to conserved hypothetical protein -
Nasonia vitripennis
Length = 511
Score = 32.7 bits (71), Expect = 6.7
Identities = 18/66 (27%), Positives = 32/66 (48%)
Frame = +2
Query: 149 DEVQEVRQTRDPITSFKEKVINNQLVTPDQLKEIDAKVRKETDEASKQAKADPEIPIEEL 328
D+V E Q ++P +++ VT +L+ + R+ + + Q DPEI ++ L
Sbjct: 409 DQVLEQAQ-KNPTKVSVAELLQQLTVTQAELENVKVMYRRILESRNSQGALDPEITLQFL 467
Query: 329 SGDIYY 346
IYY
Sbjct: 468 KSAIYY 473
>UniRef50_UPI0000D56C7C Cluster: PREDICTED: similar to CG14039-PE,
isoform E; n=1; Tribolium castaneum|Rep: PREDICTED:
similar to CG14039-PE, isoform E - Tribolium castaneum
Length = 492
Score = 32.7 bits (71), Expect = 6.7
Identities = 25/87 (28%), Positives = 42/87 (48%)
Frame = +2
Query: 86 METYRYSGHSMSDPGTSYRTRDEVQEVRQTRDPITSFKEKVINNQLVTPDQLKEIDAKVR 265
+E YR GH ++ + V E+ + S E ++ VT ++L+ I A R
Sbjct: 378 LEMYR-QGHEAAN----LERENRVMEIAKQGPSRISVPE-LLEELQVTKNELENIKAMYR 431
Query: 266 KETDEASKQAKADPEIPIEELSGDIYY 346
+ EA ++K DPEI ++ L +YY
Sbjct: 432 -QLIEAKNKSKIDPEITLQFLKSAVYY 457
>UniRef50_UPI000049936A Cluster: Activator 1 140 kDa subunit; n=1;
Entamoeba histolytica HM-1:IMSS|Rep: Activator 1 140 kDa
subunit - Entamoeba histolytica HM-1:IMSS
Length = 718
Score = 32.7 bits (71), Expect = 6.7
Identities = 19/64 (29%), Positives = 33/64 (51%)
Frame = +2
Query: 149 DEVQEVRQTRDPITSFKEKVINNQLVTPDQLKEIDAKVRKETDEASKQAKADPEIPIEEL 328
DE+ ++ + + + FK N+ +LK+ V KET +SK+ K + E +EE+
Sbjct: 639 DEMVKIGISLEKVELFKSVSTANKTKFTKELKQATTPVIKETKGSSKKTKKEYEDDLEEM 698
Query: 329 SGDI 340
S I
Sbjct: 699 SESI 702
>UniRef50_Q6ZXZ8 Cluster: Nitrous oxide reductase precursor; n=13;
Proteobacteria|Rep: Nitrous oxide reductase precursor -
Wolinella succinogenes
Length = 864
Score = 32.7 bits (71), Expect = 6.7
Identities = 28/122 (22%), Positives = 54/122 (44%), Gaps = 2/122 (1%)
Frame = +2
Query: 50 YCTSGKGPLLIEMETYRYSGHSMSDPGTSYRTRDEVQEVRQTRDPITSFKEKVINNQLVT 229
YCT L +EM Y Y + DP Y + E++ + +++ + S +KVI T
Sbjct: 622 YCTEFCSALHLEMMGYLY----VKDPKKKYESVKELKLQKMSKEQLESEYKKVIATNKAT 677
Query: 230 PDQLKEIDAKVRKETDEASKQAKADPEIPIEELS--GDIYYSNLEPFIRGTHPGAQLQHI 403
D ++ + ++ + + K+ E +++ G++ E + +G GA L
Sbjct: 678 DDVIQSVVKFLKDKNYAKYPKVKSLVEDALDQYGKIGEVKAKADESYKKGDVNGAILWEY 737
Query: 404 QV 409
QV
Sbjct: 738 QV 739
>UniRef50_A1GCL6 Cluster: Transketolase-like; n=2; Salinispora|Rep:
Transketolase-like - Salinispora arenicola CNS205
Length = 805
Score = 32.7 bits (71), Expect = 6.7
Identities = 26/107 (24%), Positives = 46/107 (42%), Gaps = 5/107 (4%)
Frame = +2
Query: 2 GMDVIATREATKFAIDYCTSGKGPLLIEMETYRYSGHSMSDPGTSYRTRDEVQEVRQTRD 181
G +++ A+ + + P ++ + T R GH+ +D T+YRT E+ RD
Sbjct: 311 GTNLVEAYAVADEAVRWVRRHRRPAVLHLSTVRLMGHAGADAETAYRTTTEI-AADLDRD 369
Query: 182 PITSFKEKVINNQLVTPDQL----KEIDAKVRKETDEASKQAK-ADP 307
P+ + + L EI +VR+ +E + K ADP
Sbjct: 370 PLLVTARLLTGAGVAAGADLLARYDEIGWQVRRIAEEVLDEPKLADP 416
>UniRef50_Q6Z707 Cluster: Non-ribosomal peptide synthetase modules
and related proteins-like; n=1; Oryza sativa (japonica
cultivar-group)|Rep: Non-ribosomal peptide synthetase
modules and related proteins-like - Oryza sativa subsp.
japonica (Rice)
Length = 623
Score = 32.7 bits (71), Expect = 6.7
Identities = 20/58 (34%), Positives = 26/58 (44%)
Frame = +1
Query: 121 RPGNVVPHEGRGPGGAPDQGPDHLLQGEGHQQPTRHSRSVKGNRRESTQGNRRGFETG 294
RPG+ GRG GG D + Q+P R V+G RR+ + RRG G
Sbjct: 481 RPGDAASARGRGGGGRADGAAQVRRRPALGQEP---ERGVRGRRRQVRRRARRGVHEG 535
>UniRef50_A7SY99 Cluster: Predicted protein; n=1; Nematostella
vectensis|Rep: Predicted protein - Nematostella
vectensis
Length = 760
Score = 32.7 bits (71), Expect = 6.7
Identities = 29/105 (27%), Positives = 44/105 (41%), Gaps = 4/105 (3%)
Frame = +2
Query: 29 ATKFAID--YCTSGKGPLLIEMETYRYSGHSMSDPGTSYRTRDEVQEVRQTRDPITSFKE 202
A +++D Y + L E+E Y + P DE E T DP+ E
Sbjct: 183 AYSYSLDKRYMETSLDELAFEIEAYEAESRGETKPSDVIDETDEAAERLVTMDPVFETTE 242
Query: 203 KVINNQLVTPDQLKEIDAKVRKE--TDEASKQAKADPEIPIEELS 331
V Q TPD K++KE ++E S +AK + EE++
Sbjct: 243 VVEEAQEPTPD-----PEKLQKELCSEEKSDEAKLETVNKTEEVN 282
>UniRef50_A7ATF7 Cluster: Putative uncharacterized protein; n=1;
Babesia bovis|Rep: Putative uncharacterized protein -
Babesia bovis
Length = 1068
Score = 32.7 bits (71), Expect = 6.7
Identities = 13/45 (28%), Positives = 28/45 (62%)
Frame = +2
Query: 209 INNQLVTPDQLKEIDAKVRKETDEASKQAKADPEIPIEELSGDIY 343
++ +++P+ +KE+DAK+ K ++ SK +AD + L ++Y
Sbjct: 502 MDKTILSPNNMKEVDAKIGKMFEKRSKDKEADLGSALRFLRNNVY 546
>UniRef50_Q4UKI8 Cluster: 2-oxoglutarate dehydrogenase E1 component;
n=14; Rickettsia|Rep: 2-oxoglutarate dehydrogenase E1
component - Rickettsia felis (Rickettsia azadi)
Length = 977
Score = 32.7 bits (71), Expect = 6.7
Identities = 19/99 (19%), Positives = 45/99 (45%)
Frame = +2
Query: 2 GMDVIATREATKFAIDYCTSGKGPLLIEMETYRYSGHSMSDPGTSYRTRDEVQEVRQTRD 181
G D+ A +AT A++Y +++E+ YR GH+ D Y ++
Sbjct: 467 GDDIEAVLKATNIAVEYRQKFGKDVVVEIICYRKYGHNEGDE-PMYTQGKMYNIIKSKPT 525
Query: 182 PITSFKEKVINNQLVTPDQLKEIDAKVRKETDEASKQAK 298
P + +++ + ++ + ++ + + + D+ +QAK
Sbjct: 526 PGNIYANELVKSGIIDNNYFAKLKEEFKAKLDKEFEQAK 564
>UniRef50_UPI000150A2A6 Cluster: Kelch motif family protein; n=1;
Tetrahymena thermophila SB210|Rep: Kelch motif family
protein - Tetrahymena thermophila SB210
Length = 646
Score = 32.3 bits (70), Expect = 8.9
Identities = 14/37 (37%), Positives = 21/37 (56%)
Frame = +2
Query: 311 IPIEELSGDIYYSNLEPFIRGTHPGAQLQHIQVAARK 421
I +E + ++ + NL PFI+G P + HI V RK
Sbjct: 498 IDLEPVETELKWENLTPFIKGQPPAPRHGHISVLVRK 534
>UniRef50_UPI0000499807 Cluster: UV excision repair protein RAD23;
n=1; Entamoeba histolytica HM-1:IMSS|Rep: UV excision
repair protein RAD23 - Entamoeba histolytica HM-1:IMSS
Length = 360
Score = 32.3 bits (70), Expect = 8.9
Identities = 20/67 (29%), Positives = 35/67 (52%)
Frame = +2
Query: 128 GTSYRTRDEVQEVRQTRDPITSFKEKVINNQLVTPDQLKEIDAKVRKETDEASKQAKADP 307
G D Q +T++ + +E I Q +TP++L EI +V +E E ++Q + DP
Sbjct: 155 GNPLENFDMFQPTEETQNEMV--QEPPIEIQ-ITPEELDEIIDEVEEEDPELAEQMREDP 211
Query: 308 EIPIEEL 328
E+ + L
Sbjct: 212 ELAMNYL 218
>UniRef50_UPI000023E47E Cluster: hypothetical protein FG05604.1;
n=1; Gibberella zeae PH-1|Rep: hypothetical protein
FG05604.1 - Gibberella zeae PH-1
Length = 397
Score = 32.3 bits (70), Expect = 8.9
Identities = 20/47 (42%), Positives = 22/47 (46%)
Frame = -1
Query: 413 QRPGCAATAPRGGCRG*KVPGSSNICPRRAPLLGSQGRP*PVSKPRR 273
QRPG AA AP G G PG N P +GRP P +K R
Sbjct: 192 QRPGAAAAAP-SGYAGTAKPGQRNGTPVSGTGRDPRGRPMPPAKQER 237
>UniRef50_Q2S3D2 Cluster: 2-oxoglutarate dehydrogenase, E1 component;
n=3; Bacteria|Rep: 2-oxoglutarate dehydrogenase, E1
component - Salinibacter ruber (strain DSM 13855)
Length = 1243
Score = 32.3 bits (70), Expect = 8.9
Identities = 19/88 (21%), Positives = 40/88 (45%)
Frame = +2
Query: 35 KFAIDYCTSGKGPLLIEMETYRYSGHSMSDPGTSYRTRDEVQEVRQTRDPITSFKEKVIN 214
+ A +Y ++I+M YR GH+ D T + +++ + R P + E ++
Sbjct: 740 RLAFEYRQRFNKDVVIDMMCYRVHGHNEGDEPT-FTQPLLYEKIEEKRSPRKLYTEMLLR 798
Query: 215 NQLVTPDQLKEIDAKVRKETDEASKQAK 298
+ PD+ +++ R EA ++ K
Sbjct: 799 RGEIEPDEAEQMLDDYRGRLQEAFERTK 826
>UniRef50_Q02AM5 Cluster: CRISPR-associated protein, Csm2 family;
n=1; Solibacter usitatus Ellin6076|Rep:
CRISPR-associated protein, Csm2 family - Solibacter
usitatus (strain Ellin6076)
Length = 178
Score = 32.3 bits (70), Expect = 8.9
Identities = 24/60 (40%), Positives = 28/60 (46%), Gaps = 1/60 (1%)
Frame = +1
Query: 139 PHEGRGP-GGAPDQGPDHLLQGEGHQQPTRHSRSVKGNRRESTQGNRRGFETG*GRP*DP 315
P EGRGP GG+P GP G + R G R G+RRGF+ GRP P
Sbjct: 14 PREGRGPQGGSPQGGPPRGGPPRGDRGGER-----GGERGGDRGGDRRGFDR--GRPEGP 66
>UniRef50_A5P1Z2 Cluster: Riboflavin biosynthesis protein RibD;
n=10; Alphaproteobacteria|Rep: Riboflavin biosynthesis
protein RibD - Methylobacterium sp. 4-46
Length = 579
Score = 32.3 bits (70), Expect = 8.9
Identities = 18/57 (31%), Positives = 23/57 (40%)
Frame = +1
Query: 118 VRPGNVVPHEGRGPGGAPDQGPDHLLQGEGHQQPTRHSRSVKGNRRESTQGNRRGFE 288
VRP + R P AP +G GE H+ P R R G +R + G E
Sbjct: 56 VRPRQAAALDRRRPAQAPGRGRPRRAAGERHRPPARERRRGGGEQRGDRRTRHGGAE 112
>UniRef50_A5P159 Cluster: Major facilitator superfamily MFS_1
precursor; n=8; Alphaproteobacteria|Rep: Major
facilitator superfamily MFS_1 precursor -
Methylobacterium sp. 4-46
Length = 876
Score = 32.3 bits (70), Expect = 8.9
Identities = 33/99 (33%), Positives = 44/99 (44%), Gaps = 1/99 (1%)
Frame = +1
Query: 115 DVRPGNVVPHEGRGPGGAPDQG-PDHLLQGEGHQQPTRHSRSVKGNRRESTQGNRRGFET 291
++RPG +P + R GA D+G P +G R R+ R+ RRG
Sbjct: 401 ELRPGPDLPDDDRLRAGALDRGRPGRRSRGR------RRGRAGSPGDRDLHDRARRGPGR 454
Query: 292 G*GRP*DPNRGALRGHILLEPGTFHPRHPPRGAVAAHPG 408
G R RG +RG +LL PG R PR AV + G
Sbjct: 455 GQRR-----RGLVRGRVLLRPGRVSAR--PRLAVVSALG 486
>UniRef50_A4YXU9 Cluster: Flagellar basal-body rod protein FlgC;
n=16; Alphaproteobacteria|Rep: Flagellar basal-body rod
protein FlgC - Bradyrhizobium sp. (strain ORS278)
Length = 141
Score = 32.3 bits (70), Expect = 8.9
Identities = 17/49 (34%), Positives = 27/49 (55%), Gaps = 4/49 (8%)
Frame = +2
Query: 242 KEIDAKV----RKETDEASKQAKADPEIPIEELSGDIYYSNLEPFIRGT 376
+ +DAKV + D++S + K DP P + SG++ Y N+ P I T
Sbjct: 61 RALDAKVVTLGKVVPDQSSFRVKYDPSNPAADASGNVKYPNVNPLIEMT 109
>UniRef50_Q9BLX9 Cluster: Intermediate filament protein IF-B; n=1;
Ciona intestinalis|Rep: Intermediate filament protein
IF-B - Ciona intestinalis (Transparent sea squirt)
Length = 441
Score = 32.3 bits (70), Expect = 8.9
Identities = 15/50 (30%), Positives = 26/50 (52%)
Frame = +2
Query: 122 DPGTSYRTRDEVQEVRQTRDPITSFKEKVINNQLVTPDQLKEIDAKVRKE 271
+ GT+ ++ EV E+R+ +T+ E NN QL+E+D + E
Sbjct: 274 EAGTNKSSKTEVLELRRQLQSVTTELESTANNNSAIETQLQELDIRYHNE 323
>UniRef50_A0BYZ2 Cluster: Chromosome undetermined scaffold_138,
whole genome shotgun sequence; n=2; Paramecium
tetraurelia|Rep: Chromosome undetermined scaffold_138,
whole genome shotgun sequence - Paramecium tetraurelia
Length = 337
Score = 32.3 bits (70), Expect = 8.9
Identities = 16/64 (25%), Positives = 34/64 (53%)
Frame = +2
Query: 140 RTRDEVQEVRQTRDPITSFKEKVINNQLVTPDQLKEIDAKVRKETDEASKQAKADPEIPI 319
+ +++VQ+ Q ++ + E+V Q+ Q E+DA+ ++++ + +Q PEI
Sbjct: 252 QVQEQVQQTEQVQEQVQQ-TEQVQEQQVQEQQQQVEVDAQQQEQSQQQDQQQSETPEIQQ 310
Query: 320 EELS 331
E S
Sbjct: 311 NETS 314
>UniRef50_A6SRK7 Cluster: Predicted protein; n=1; Botryotinia
fuckeliana B05.10|Rep: Predicted protein - Botryotinia
fuckeliana B05.10
Length = 369
Score = 32.3 bits (70), Expect = 8.9
Identities = 15/58 (25%), Positives = 31/58 (53%)
Frame = +2
Query: 149 DEVQEVRQTRDPITSFKEKVINNQLVTPDQLKEIDAKVRKETDEASKQAKADPEIPIE 322
+E ++V +P++S ++ + TP K KV + +EA ++A+AD + +E
Sbjct: 144 EEQEDVNMDDEPVSSPPKRASRSTKATPKTKKSNGKKVAPQEEEAEEEAQADVDNEVE 201
>UniRef50_Q10030 Cluster: Uncharacterized protein C27D6.1; n=2;
Caenorhabditis|Rep: Uncharacterized protein C27D6.1 -
Caenorhabditis elegans
Length = 782
Score = 32.3 bits (70), Expect = 8.9
Identities = 20/71 (28%), Positives = 36/71 (50%)
Frame = +2
Query: 110 HSMSDPGTSYRTRDEVQEVRQTRDPITSFKEKVINNQLVTPDQLKEIDAKVRKETDEASK 289
H + +Y R+ E RQT+ + S + ++ N+ KEI+A+ K D A++
Sbjct: 211 HKVFQVAATYTIRENRSE-RQTKVKLESLERRLKANEKAR----KEIEAEAEKWKDRATR 265
Query: 290 QAKADPEIPIE 322
+K PE+ +E
Sbjct: 266 NSKRLPELELE 276
>UniRef50_Q02388 Cluster: Collagen alpha-1(VII) chain precursor; n=30;
Eumetazoa|Rep: Collagen alpha-1(VII) chain precursor -
Homo sapiens (Human)
Length = 2944
Score = 32.3 bits (70), Expect = 8.9
Identities = 29/98 (29%), Positives = 40/98 (40%), Gaps = 5/98 (5%)
Frame = +1
Query: 124 PGNVVPHEGRGPGGAPDQGPDHLLQGEGH-----QQPTRHSRSVKGNRRESTQGNRRGFE 288
PG V + GPG + +QGP L +G Q + R V G + + + RG +
Sbjct: 2090 PGPKVSVDEPGPGLSGEQGPPGLKGAKGEPGSNGDQGPKGDRGVPGIKGDRGEPGPRGQD 2149
Query: 289 TG*GRP*DPNRGALRGHILLEPGTFHPRHPPRGAVAAH 402
G P + G +PG PR PP G V H
Sbjct: 2150 GNPGLPGERGMAGPEG----KPGLQGPRGPP-GPVGGH 2182
Database: uniref50
Posted date: Oct 5, 2007 11:19 AM
Number of letters in database: 575,637,011
Number of sequences in database: 1,657,284
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 615,559,672
Number of Sequences: 1657284
Number of extensions: 13376896
Number of successful extensions: 48108
Number of sequences better than 10.0: 212
Number of HSP's better than 10.0 without gapping: 45221
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 47975
length of database: 575,637,011
effective HSP length: 97
effective length of database: 414,880,463
effective search space used: 41902926763
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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