BLASTX 2.2.12 [Aug-07-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= I10A02NGRL0005_J18 (549 letters) Database: nematostella 59,808 sequences; 16,821,457 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value SB_39834| Best HMM Match : Kazal_1 (HMM E-Value=0) 74 9e-14 SB_31788| Best HMM Match : Kazal_1 (HMM E-Value=0) 73 2e-13 SB_18275| Best HMM Match : Kazal_1 (HMM E-Value=0) 67 8e-12 SB_42767| Best HMM Match : Thyroglobulin_1 (HMM E-Value=0) 62 3e-10 SB_6686| Best HMM Match : Kazal_1 (HMM E-Value=0) 60 2e-09 SB_41491| Best HMM Match : Kazal_1 (HMM E-Value=1.1e-12) 56 3e-08 SB_6080| Best HMM Match : No HMM Matches (HMM E-Value=.) 56 3e-08 SB_15403| Best HMM Match : CH (HMM E-Value=0) 51 5e-07 SB_53017| Best HMM Match : Kazal_1 (HMM E-Value=0) 50 2e-06 SB_39831| Best HMM Match : Kazal_1 (HMM E-Value=2.4e-19) 48 7e-06 SB_135| Best HMM Match : Kazal_1 (HMM E-Value=2.9e-19) 47 9e-06 SB_11826| Best HMM Match : Kazal_1 (HMM E-Value=1.2e-16) 47 9e-06 SB_44384| Best HMM Match : Kazal_1 (HMM E-Value=1.4e-21) 46 2e-05 SB_46203| Best HMM Match : No HMM Matches (HMM E-Value=.) 45 4e-05 SB_40582| Best HMM Match : Kazal_1 (HMM E-Value=0) 45 4e-05 SB_36847| Best HMM Match : No HMM Matches (HMM E-Value=.) 45 5e-05 SB_7591| Best HMM Match : No HMM Matches (HMM E-Value=.) 44 6e-05 SB_50468| Best HMM Match : Kazal_1 (HMM E-Value=1.3e-15) 44 1e-04 SB_33512| Best HMM Match : Kazal_1 (HMM E-Value=2.6e-20) 41 8e-04 SB_44627| Best HMM Match : Kazal_1 (HMM E-Value=3.19496e-43) 40 0.001 SB_33374| Best HMM Match : No HMM Matches (HMM E-Value=.) 40 0.001 SB_6081| Best HMM Match : No HMM Matches (HMM E-Value=.) 39 0.002 SB_23052| Best HMM Match : No HMM Matches (HMM E-Value=.) 39 0.003 SB_35516| Best HMM Match : Kazal_1 (HMM E-Value=0) 39 0.003 SB_37368| Best HMM Match : Kazal_1 (HMM E-Value=9.2e-09) 38 0.004 SB_32965| Best HMM Match : Kazal_1 (HMM E-Value=3.4e-19) 38 0.004 SB_33509| Best HMM Match : Kazal_1 (HMM E-Value=2.3e-26) 37 0.012 SB_33373| Best HMM Match : No HMM Matches (HMM E-Value=.) 37 0.012 SB_58159| Best HMM Match : No HMM Matches (HMM E-Value=.) 36 0.022 SB_30470| Best HMM Match : No HMM Matches (HMM E-Value=.) 34 0.067 SB_17430| Best HMM Match : Kazal_1 (HMM E-Value=1e-07) 34 0.067 SB_3798| Best HMM Match : No HMM Matches (HMM E-Value=.) 34 0.067 SB_59417| Best HMM Match : No HMM Matches (HMM E-Value=.) 34 0.067 SB_57668| Best HMM Match : No HMM Matches (HMM E-Value=.) 34 0.088 SB_13131| Best HMM Match : No HMM Matches (HMM E-Value=.) 34 0.088 SB_28600| Best HMM Match : EGF_CA (HMM E-Value=4.2e-40) 33 0.20 SB_27078| Best HMM Match : Kazal_2 (HMM E-Value=7.6e-07) 33 0.20 SB_9563| Best HMM Match : Kazal_1 (HMM E-Value=1.7e-07) 33 0.20 SB_45072| Best HMM Match : Kazal_2 (HMM E-Value=5.8e-06) 31 0.47 SB_25348| Best HMM Match : Kazal_1 (HMM E-Value=5.3e-09) 31 0.62 SB_14008| Best HMM Match : Kazal_1 (HMM E-Value=5.3e-09) 31 0.62 SB_22525| Best HMM Match : No HMM Matches (HMM E-Value=.) 31 0.82 SB_56344| Best HMM Match : Kazal_2 (HMM E-Value=1.5e-09) 31 0.82 SB_5272| Best HMM Match : No HMM Matches (HMM E-Value=.) 30 1.1 SB_43077| Best HMM Match : No HMM Matches (HMM E-Value=.) 30 1.4 SB_7030| Best HMM Match : Kazal_2 (HMM E-Value=4.6e-08) 30 1.4 SB_29074| Best HMM Match : Kazal_2 (HMM E-Value=3.3e-16) 29 1.9 SB_57638| Best HMM Match : F5_F8_type_C (HMM E-Value=1.7e-11) 29 1.9 SB_45722| Best HMM Match : No HMM Matches (HMM E-Value=.) 29 1.9 SB_27392| Best HMM Match : Kazal_1 (HMM E-Value=0.00072) 29 2.5 SB_18764| Best HMM Match : No HMM Matches (HMM E-Value=.) 29 2.5 SB_2561| Best HMM Match : No HMM Matches (HMM E-Value=.) 28 4.4 SB_20039| Best HMM Match : LRR_1 (HMM E-Value=0.0061) 28 5.8 SB_38207| Best HMM Match : No HMM Matches (HMM E-Value=.) 27 7.6 SB_28622| Best HMM Match : CcmD (HMM E-Value=0.55) 27 7.6 SB_16978| Best HMM Match : No HMM Matches (HMM E-Value=.) 27 7.6 >SB_39834| Best HMM Match : Kazal_1 (HMM E-Value=0) Length = 293 Score = 73.7 bits (173), Expect = 9e-14 Identities = 38/95 (40%), Positives = 59/95 (62%), Gaps = 2/95 (2%) Frame = -2 Query: 548 EYAPVCGSNGKTYANKCSLECTQ-KIIPSLKMEHDGECQGAKLASLHPCICTREKGPVCG 372 E PVCGS+GKTY N C + ++ L+++H G C G++ P IC + PVCG Sbjct: 125 ELNPVCGSDGKTYDNPCVFKIAVCQMNGQLRLKHRGAC-GSRPDKCAP-ICNKMYQPVCG 182 Query: 371 SDGVTYSNLCLLKCASL-SKPSLSIEHTGPCDNNR 270 SD VTYSN C+L+ A+ S +++++H G C +++ Sbjct: 183 SDNVTYSNPCMLRSATCKSNGTITMKHRGKCGSSQ 217 Score = 59.3 bits (137), Expect = 2e-09 Identities = 41/111 (36%), Positives = 54/111 (48%), Gaps = 23/111 (20%) Frame = -2 Query: 545 YAPVCGSNGKTYANKCSL-ECTQKIIPSLKMEHDGEC---QG----------------AK 426 Y PVCG++GKTY NKC L T + ++ + + GEC +G A Sbjct: 52 YMPVCGTDGKTYGNKCMLGAATCRSNGTITLAYPGECIVEKGYYCEKDAADAIKMILEAV 111 Query: 425 LASLHPCI--CTREKGPVCGSDGVTYSNLCLLKCASLS-KPSLSIEHTGPC 282 S C+ CT+E PVCGSDG TY N C+ K A L ++H G C Sbjct: 112 WGSSLRCMRRCTKELNPVCGSDGKTYDNPCVFKIAVCQMNGQLRLKHRGAC 162 Score = 42.7 bits (96), Expect = 2e-04 Identities = 23/72 (31%), Positives = 37/72 (51%), Gaps = 3/72 (4%) Frame = -2 Query: 488 CTQKIIPSLKMEHDGECQGAKLASLHPCI--CTREKGPVCGSDGVTYSNLCLLKCASL-S 318 C + ++ +E D LA + PC+ C PVCG+DG TY N C+L A+ S Sbjct: 17 CAEGGFSTINIEKDFLFDFEGLAIVDPCVRPCPAIYMPVCGTDGKTYGNKCMLGAATCRS 76 Query: 317 KPSLSIEHTGPC 282 ++++ + G C Sbjct: 77 NGTITLAYPGEC 88 >SB_31788| Best HMM Match : Kazal_1 (HMM E-Value=0) Length = 352 Score = 72.9 bits (171), Expect = 2e-13 Identities = 41/100 (41%), Positives = 56/100 (56%), Gaps = 14/100 (14%) Frame = -2 Query: 539 PVCGSNGKTYANKCSLECTQKIIPS-----LKMEHDGECQGAKLASLHPCI----CTREK 387 PVCGS+GKTY N C L + +P L ++H G C GA + + PC+ C R++ Sbjct: 246 PVCGSDGKTYTNGCELATAKCALPKGQKRQLTLKHRGPC-GAPITA-KPCMTKQKCRRKR 303 Query: 386 GPVCGSDGVTYSNLCLLKCASL-----SKPSLSIEHTGPC 282 PVCGSDGVTY + C L+ A + L ++H GPC Sbjct: 304 DPVCGSDGVTYRSKCHLRVAKCLRKRKRRSQLVLKHMGPC 343 Score = 62.1 bits (144), Expect = 3e-10 Identities = 38/96 (39%), Positives = 51/96 (53%), Gaps = 10/96 (10%) Frame = -2 Query: 539 PVCGSNGKTYANKCSL---EC-TQKIIPSLKMEHDGECQG-AKLASLHPCICTREKGPVC 375 P+CG + KTY N C +C +K LK+++ G C S P C ++ PVC Sbjct: 189 PICGEDEKTYRNLCLFLVAKCKAKKDGRRLKLKYRGACGNPTPRKSCPPRTCPKQDKPVC 248 Query: 374 GSDGVTYSNLCLL---KCA--SLSKPSLSIEHTGPC 282 GSDG TY+N C L KCA K L+++H GPC Sbjct: 249 GSDGKTYTNGCELATAKCALPKGQKRQLTLKHRGPC 284 Score = 46.4 bits (105), Expect = 2e-05 Identities = 31/97 (31%), Positives = 44/97 (45%), Gaps = 10/97 (10%) Frame = -2 Query: 536 VCGSNGKTYANKCSL---ECTQKII-PSLKMEHDGECQGAKLASLHP--CICTREKGPVC 375 VC SNG T++ C +C + +L + + G C K + P C + P+C Sbjct: 132 VCDSNGTTHSTYCHFKVAQCKAALAGQNLSLRYKGVCGKPKRQVVCPQESQCDLKNRPIC 191 Query: 374 GSDGVTYSNLCLL---KC-ASLSKPSLSIEHTGPCDN 276 G D TY NLCL KC A L +++ G C N Sbjct: 192 GEDEKTYRNLCLFLVAKCKAKKDGRRLKLKYRGACGN 228 Score = 35.9 bits (79), Expect = 0.022 Identities = 17/44 (38%), Positives = 26/44 (59%), Gaps = 4/44 (9%) Frame = -2 Query: 401 CTREKGPVCGSDGVTYSNLCLLK---CASLSK-PSLSIEHTGPC 282 C R PVCGSD V+YSN+C + C ++ + L +++ G C Sbjct: 39 CPRILTPVCGSDRVSYSNMCAFRNAQCLAVEQGQKLLLQYEGEC 82 Score = 29.5 bits (63), Expect = 1.9 Identities = 13/38 (34%), Positives = 22/38 (57%), Gaps = 4/38 (10%) Frame = -2 Query: 539 PVCGSNGKTYANKCSLECTQKII----PSLKMEHDGEC 438 PVCGS+ +Y+N C+ Q + L ++++GEC Sbjct: 45 PVCGSDRVSYSNMCAFRNAQCLAVEQGQKLLLQYEGEC 82 >SB_18275| Best HMM Match : Kazal_1 (HMM E-Value=0) Length = 325 Score = 67.3 bits (157), Expect = 8e-12 Identities = 43/115 (37%), Positives = 54/115 (46%), Gaps = 26/115 (22%) Frame = -2 Query: 548 EYAPVCGSNGKTYANKCSLECTQ-KIIPSLKMEHDGECQGAKLASLHPC----------- 405 EYAPVCGS+GKTY N C+LE K + + G C + L+ PC Sbjct: 49 EYAPVCGSDGKTYPNPCALEVESCKTNTRISVIKKGSCDDSALSD--PCDIALCSFPQSI 106 Query: 404 --------------ICTREKGPVCGSDGVTYSNLCLLKCASLSKPSLSIEHTGPC 282 CTRE PVCG+D TY N+CLL+ A+ L + H GPC Sbjct: 107 CVNVNGTATCECPRACTRELMPVCGTDQKTYDNMCLLERAACKDDGLMLAHEGPC 161 Score = 54.4 bits (125), Expect = 6e-08 Identities = 39/118 (33%), Positives = 51/118 (43%), Gaps = 29/118 (24%) Frame = -2 Query: 548 EYAPVCGSNGKTYANKCSLECTQKIIPSLKMEHDGECQG-AKLASLHPC----------- 405 E PVCG++ KTY N C LE L + H+G C +S+ PC Sbjct: 125 ELMPVCGTDQKTYDNMCLLERAACKDDGLMLAHEGPCPTKVNESSVSPCEISLCSFPRPI 184 Query: 404 --------------ICTREKGPVCGSDGVTYSNLCLLK---CASLSKPSLSIEHTGPC 282 +CT + PVCGSD TY+NLC L+ C + L + H GPC Sbjct: 185 CVEVNGTATCECPKVCTLDYTPVCGSDNKTYANLCNLEVEACKPENTDKLQLLHDGPC 242 Score = 46.4 bits (105), Expect = 2e-05 Identities = 21/44 (47%), Positives = 25/44 (56%), Gaps = 1/44 (2%) Frame = -2 Query: 410 PCICTREKGPVCGSDGVTYSNLCLLKCASL-SKPSLSIEHTGPC 282 P CTRE P CG+DG TY N C+L S + L + H GPC Sbjct: 280 PKACTREYKPACGTDGNTYPNRCVLAIQSCETGEKLQLAHDGPC 323 Score = 46.0 bits (104), Expect = 2e-05 Identities = 21/44 (47%), Positives = 27/44 (61%), Gaps = 1/44 (2%) Frame = -2 Query: 401 CTREKGPVCGSDGVTYSNLCLLKCASL-SKPSLSIEHTGPCDNN 273 CTRE PVCGSDG TY N C L+ S + +S+ G CD++ Sbjct: 46 CTREYAPVCGSDGKTYPNPCALEVESCKTNTRISVIKKGSCDDS 89 Score = 38.7 bits (86), Expect = 0.003 Identities = 16/38 (42%), Positives = 22/38 (57%), Gaps = 1/38 (2%) Frame = -2 Query: 548 EYAPVCGSNGKTYANKCSLECTQ-KIIPSLKMEHDGEC 438 EY P CG++G TY N+C L + L++ HDG C Sbjct: 286 EYKPACGTDGNTYPNRCVLAIQSCETGEKLQLAHDGPC 323 >SB_42767| Best HMM Match : Thyroglobulin_1 (HMM E-Value=0) Length = 6725 Score = 62.1 bits (144), Expect = 3e-10 Identities = 41/109 (37%), Positives = 55/109 (50%), Gaps = 19/109 (17%) Frame = -2 Query: 548 EYAPVCGSNGKTYANKCSLE---CTQ-KIIPSLKMEHD------------GECQGAKLAS 417 EY+P+CGS+GKTY N+C +E C Q K + + D EC + Sbjct: 5161 EYSPLCGSDGKTYDNQCEMERASCLQNKDLTGKPGKCDPCEDYTCTSPPYSECTAINGSP 5220 Query: 416 LHPC--ICTREKGPVCGSDGVTYSNLCLLKCASLSKPSL-SIEHTGPCD 279 + C ICT E PVCG+DG +Y N CLL+ AS + L + G CD Sbjct: 5221 VCTCNSICTLEYAPVCGTDGQSYDNECLLQTASCQRNELIEVATQGTCD 5269 Score = 47.6 bits (108), Expect = 7e-06 Identities = 37/109 (33%), Positives = 52/109 (47%), Gaps = 20/109 (18%) Frame = -2 Query: 548 EYAPVCGSNGKTYANKCSLE---CTQKIIPSLKMEHDGE-CQG----------AKLASLH 411 EYAPVCG++G++Y N+C L+ C + + + + + C G K Sbjct: 5231 EYAPVCGTDGQSYDNECLLQTASCQRNELIEVATQGTCDPCVGFTCVAPPYSYCKARDGR 5290 Query: 410 P---C--ICTREKGPVCGSDGVTYSNLCLLKCASLSKPSL-SIEHTGPC 282 P C IC+ PVCG+DG YSN C L+ AS K L + G C Sbjct: 5291 PECVCDGICSLVYAPVCGTDGQEYSNECNLQIASCRKNELIEVASRGSC 5339 Score = 46.4 bits (105), Expect = 2e-05 Identities = 30/98 (30%), Positives = 46/98 (46%), Gaps = 17/98 (17%) Frame = -2 Query: 548 EYAPVCGSNGKTYANKCSLECT----QKIIPSLKMEHDGECQGAKLASLHP-CI------ 402 +Y PVCG++G+TY N+C+L+ + + + H CQ + + C+ Sbjct: 5558 DYTPVCGTDGETYENECTLQISSCQRNEQVEVASQGHCHPCQRSPCTVPYSRCVLIRGQA 5617 Query: 401 ------CTREKGPVCGSDGVTYSNLCLLKCASLSKPSL 306 C PVCGSDG TY+N C L+ + SL Sbjct: 5618 VCMCQSCPSINKPVCGSDGKTYNNECELRQYACKSDSL 5655 Score = 44.4 bits (100), Expect = 6e-05 Identities = 39/111 (35%), Positives = 50/111 (45%), Gaps = 25/111 (22%) Frame = -2 Query: 539 PVCGSNGKTYANKCSLE---C-TQKIIPSLKMEH-DGECQGAKLAS-----------LHP 408 PVCGS+GK Y N+C+L C T +I ++ + G C G S Sbjct: 5799 PVCGSDGKNYDNECNLRQNACKTNTLITVVRRDACPGPCSGVTCDSPPYSTCKEQDDKPT 5858 Query: 407 CICTRE----KGPVCGSDGVTYSNLCLLKCASL-SKPSLSI----EHTGPC 282 C+C PV GSDG Y N CLLK A+ SK + I + GPC Sbjct: 5859 CVCVEPCPEILKPVYGSDGKDYDNECLLKLAACKSKSRILIAGFGRYPGPC 5909 Score = 41.9 bits (94), Expect = 3e-04 Identities = 20/44 (45%), Positives = 24/44 (54%) Frame = -2 Query: 410 PCICTREKGPVCGSDGVTYSNLCLLKCASLSKPSLSIEHTGPCD 279 P ICT E P+CGSDG TY N C ++ AS + G CD Sbjct: 5155 PDICTFEYSPLCGSDGKTYDNQCEMERASCLQNKDLTGKPGKCD 5198 Score = 40.7 bits (91), Expect = 8e-04 Identities = 38/111 (34%), Positives = 50/111 (45%), Gaps = 25/111 (22%) Frame = -2 Query: 539 PVCGSNGKTYANKCSLECT-----QKIIPSLKMEHDGECQGA----------KLASLHP- 408 PV GS+GK Y N+C L+ T +I+ + + G C G K+ P Sbjct: 5943 PVYGSDGKDYDNECLLKLTACKSKSRILIAGFGRYPGPCSGVTCDSPPYSTCKVQDDKPT 6002 Query: 407 CICTRE----KGPVCGSDGVTYSNLCLLKCASL-SKPSLSI----EHTGPC 282 C+C PV GSDG Y N CLLK A+ SK + I + GPC Sbjct: 6003 CVCVEPCPEILKPVYGSDGKDYDNECLLKLAACKSKSRILIAGFGRYPGPC 6053 Score = 39.9 bits (89), Expect = 0.001 Identities = 39/111 (35%), Positives = 50/111 (45%), Gaps = 25/111 (22%) Frame = -2 Query: 539 PVCGSNGKTYANKCSLE---CTQK--IIPSLKMEHDGECQGA----------KLASLHP- 408 PV GS+GK Y N+C L+ C K I+ + + G C G K+ P Sbjct: 6015 PVYGSDGKDYDNECLLKLAACKSKSRILIAGFGRYPGPCSGVTCDSPPYSTCKVQDDKPT 6074 Query: 407 CICTRE----KGPVCGSDGVTYSNLCLLKCASL-SKPSLSI----EHTGPC 282 C+C PV GSDG Y N CLLK A+ SK + I + GPC Sbjct: 6075 CVCVEPCPEILKPVYGSDGKDYDNECLLKLAACKSKSRILIAGFGRYPGPC 6125 Score = 39.5 bits (88), Expect = 0.002 Identities = 39/111 (35%), Positives = 50/111 (45%), Gaps = 25/111 (22%) Frame = -2 Query: 539 PVCGSNGKTYANKCSLE---CTQK--IIPSLKMEHDGECQGA----------KLASLHP- 408 PV GS+GK Y N+C L+ C K I+ + + G C G K+ P Sbjct: 6159 PVYGSDGKDYDNECLLKLSACKSKSRILIAGFGRYPGPCSGVTCDSPPYSTCKVQDDKPT 6218 Query: 407 CICTRE----KGPVCGSDGVTYSNLCLLKCASL-SKPSLSI----EHTGPC 282 C+C PV GSDG Y N CLLK A+ SK + I + GPC Sbjct: 6219 CVCVEPCPEILKPVYGSDGRDYDNECLLKLAACKSKSRILIAGFGRYPGPC 6269 Score = 38.7 bits (86), Expect = 0.003 Identities = 34/97 (35%), Positives = 43/97 (44%), Gaps = 20/97 (20%) Frame = -2 Query: 539 PVCGSNGKTYANKCSLE---CTQK--IIPSLKMEHDGECQGA----------KLASLHP- 408 PV GS+GK Y N+C L+ C K I+ + + G C G K+ P Sbjct: 5391 PVYGSDGKDYDNECLLKLAACKSKSRILIAGFGRYPGPCSGVTCDSPPYSTCKVQDDKPT 5450 Query: 407 CICTRE----KGPVCGSDGVTYSNLCLLKCASLSKPS 309 C+C PV GSDG Y N CLLK A+ S Sbjct: 5451 CVCVEPCPEILKPVYGSDGKDYDNECLLKLAACKSKS 5487 Score = 38.7 bits (86), Expect = 0.003 Identities = 39/111 (35%), Positives = 49/111 (44%), Gaps = 25/111 (22%) Frame = -2 Query: 539 PVCGSNGKTYANKCSLE---CTQK--IIPSLKMEHDGECQGA----------KLASLHP- 408 PV GS+GK Y N+C L+ C K I+ + + G C G K+ P Sbjct: 5871 PVYGSDGKDYDNECLLKLAACKSKSRILIAGFGRYPGPCSGVTCDSPPYSTCKVQDDKPT 5930 Query: 407 CICTRE----KGPVCGSDGVTYSNLCLLK-CASLSKPSLSI----EHTGPC 282 C+C PV GSDG Y N CLLK A SK + I + GPC Sbjct: 5931 CVCVEPCPEILKPVYGSDGKDYDNECLLKLTACKSKSRILIAGFGRYPGPC 5981 Score = 38.7 bits (86), Expect = 0.003 Identities = 39/111 (35%), Positives = 49/111 (44%), Gaps = 25/111 (22%) Frame = -2 Query: 539 PVCGSNGKTYANKCSLE---CTQK--IIPSLKMEHDGECQGA----------KLASLHP- 408 PV GS+GK Y N+C L+ C K I+ + + G C G K+ P Sbjct: 6087 PVYGSDGKDYDNECLLKLAACKSKSRILIAGFGRYPGPCSGVTCDSPPYSTCKVQDDKPT 6146 Query: 407 CICTRE----KGPVCGSDGVTYSNLCLLK-CASLSKPSLSI----EHTGPC 282 C+C PV GSDG Y N CLLK A SK + I + GPC Sbjct: 6147 CVCVEPCPEILKPVYGSDGKDYDNECLLKLSACKSKSRILIAGFGRYPGPC 6197 Score = 38.7 bits (86), Expect = 0.003 Identities = 38/111 (34%), Positives = 50/111 (45%), Gaps = 25/111 (22%) Frame = -2 Query: 539 PVCGSNGKTYANKCSLE---CTQK--IIPSLKMEHDGECQGA----------KLASLHP- 408 PV GS+G+ Y N+C L+ C K I+ + + G C G K+ P Sbjct: 6231 PVYGSDGRDYDNECLLKLAACKSKSRILIAGFGRYPGPCSGVTCDSPPYSTCKVQDDKPT 6290 Query: 407 CICTRE----KGPVCGSDGVTYSNLCLLKCASL-SKPSLSI----EHTGPC 282 C+C PV GSDG Y N CLLK A+ SK + I + GPC Sbjct: 6291 CVCVEPCPEILKPVYGSDGKDYDNECLLKLAACKSKSRILIAGFGRYPGPC 6341 Score = 38.7 bits (86), Expect = 0.003 Identities = 34/97 (35%), Positives = 43/97 (44%), Gaps = 20/97 (20%) Frame = -2 Query: 539 PVCGSNGKTYANKCSLE---CTQK--IIPSLKMEHDGECQGA----------KLASLHP- 408 PV GS+GK Y N+C L+ C K I+ + + G C G K+ P Sbjct: 6303 PVYGSDGKDYDNECLLKLAACKSKSRILIAGFGRYPGPCSGVTCDSPPYSTCKVQDDKPT 6362 Query: 407 CICTRE----KGPVCGSDGVTYSNLCLLKCASLSKPS 309 C+C PV GSDG Y N CLLK A+ S Sbjct: 6363 CVCVEPCPEILKPVYGSDGKDYDNECLLKLAACKSKS 6399 Score = 38.7 bits (86), Expect = 0.003 Identities = 39/111 (35%), Positives = 49/111 (44%), Gaps = 25/111 (22%) Frame = -2 Query: 539 PVCGSNGKTYANKCSLE---CTQK--IIPSLKMEHDGECQG----------AKLASLHP- 408 PV GS+GK Y N+C L+ C K I+ + G C G K+ P Sbjct: 6546 PVYGSDGKDYDNECLLKLAACKSKSRILIAGFGRFPGPCSGVTCDSPPYSTCKVQDDKPT 6605 Query: 407 CICTRE----KGPVCGSDGVTYSNLCLLKCASL-SKPSLSI----EHTGPC 282 C+C PV GSDG Y N CLLK A+ SK + I + GPC Sbjct: 6606 CVCVEPCPEILKPVYGSDGKDYDNECLLKLAACKSKSRILIAGFGRYPGPC 6656 Score = 38.7 bits (86), Expect = 0.003 Identities = 34/97 (35%), Positives = 43/97 (44%), Gaps = 20/97 (20%) Frame = -2 Query: 539 PVCGSNGKTYANKCSLE---CTQK--IIPSLKMEHDGECQGA----------KLASLHP- 408 PV GS+GK Y N+C L+ C K I+ + + G C G K+ P Sbjct: 6618 PVYGSDGKDYDNECLLKLAACKSKSRILIAGFGRYPGPCSGVTCDSPPYSTCKVQDDKPT 6677 Query: 407 CICTRE----KGPVCGSDGVTYSNLCLLKCASLSKPS 309 C+C PV GSDG Y N CLLK A+ S Sbjct: 6678 CVCVEPCPEILKPVYGSDGKDYDNECLLKLAACKSKS 6714 Score = 37.9 bits (84), Expect = 0.005 Identities = 17/46 (36%), Positives = 25/46 (54%), Gaps = 1/46 (2%) Frame = -2 Query: 416 LHPCICTREKGPVCGSDGVTYSNLCLLKCASLSK-PSLSIEHTGPC 282 LH C+ + PVCG+DG TY N C L+ +S + + + G C Sbjct: 5550 LHRNTCSLDYTPVCGTDGETYENECTLQISSCQRNEQVEVASQGHC 5595 Score = 35.1 bits (77), Expect = 0.038 Identities = 20/62 (32%), Positives = 31/62 (50%), Gaps = 3/62 (4%) Frame = -2 Query: 545 YAPVCGSNGKTYANKCSLECTQ-KIIPSLKMEHDGEC--QGAKLASLHPCICTREKGPVC 375 YAPVCG++G+ Y+N+C+L+ + +++ G C G AS P G C Sbjct: 5303 YAPVCGTDGQEYSNECNLQIASCRKNELIEVASRGSCPTTGPSTASPVPTTVDPCSGVTC 5362 Query: 374 GS 369 S Sbjct: 5363 DS 5364 Score = 32.3 bits (70), Expect = 0.27 Identities = 20/45 (44%), Positives = 23/45 (51%), Gaps = 5/45 (11%) Frame = -2 Query: 401 CTREKGPVCGSDGVTYSNLCLLKCASL-SKPSLSI----EHTGPC 282 C PV GSDG Y N CLLK A+ SK + I + GPC Sbjct: 5385 CPEILKPVYGSDGKDYDNECLLKLAACKSKSRILIAGFGRYPGPC 5429 Score = 31.5 bits (68), Expect = 0.47 Identities = 25/80 (31%), Positives = 32/80 (40%), Gaps = 1/80 (1%) Frame = -2 Query: 545 YAPVCGSNGKTYANKCS-LECTQKIIPSLKMEHDGECQGAKLASLHPCICTREKGPVCGS 369 Y S+ T A CS + C + K++ D + PC PV GS Sbjct: 6409 YPKTTTSSATTEAGPCSGVTCDSPPYSTCKVQDDKPT----CVCVEPC--PEILKPVYGS 6462 Query: 368 DGVTYSNLCLLKCASLSKPS 309 DG Y N CLLK A+ S Sbjct: 6463 DGKDYDNECLLKLAACKSKS 6482 Score = 31.1 bits (67), Expect = 0.62 Identities = 15/31 (48%), Positives = 16/31 (51%) Frame = -2 Query: 401 CTREKGPVCGSDGVTYSNLCLLKCASLSKPS 309 C PV GSDG Y N CLLK A+ S Sbjct: 6540 CPEILKPVYGSDGKDYDNECLLKLAACKSKS 6570 Score = 29.9 bits (64), Expect = 1.4 Identities = 12/23 (52%), Positives = 13/23 (56%) Frame = -2 Query: 401 CTREKGPVCGSDGVTYSNLCLLK 333 C PVCGSDG Y N C L+ Sbjct: 5793 CPNILDPVCGSDGKNYDNECNLR 5815 >SB_6686| Best HMM Match : Kazal_1 (HMM E-Value=0) Length = 2411 Score = 59.7 bits (138), Expect = 2e-09 Identities = 41/112 (36%), Positives = 57/112 (50%), Gaps = 22/112 (19%) Frame = -2 Query: 548 EYAPVCGSNGKTYANKC---SLECTQKIIPSLKMEHDGECQGAKLASLH----------- 411 E PVC S+G+TY N+C +L C++K S+ DG C +L S Sbjct: 893 ELRPVCASDGRTYVNECVMRALACSRK--ESVNKTKDGACDPCQLVSCRFYSKCQRRRGG 950 Query: 410 -PCIC--TRE----KGPVCGSDGVTYSNLCLLKCASLS-KPSLSIEHTGPCD 279 C+C T E VCGS+G TY+N CLLK S + + +S++H G CD Sbjct: 951 AQCVCPQTSECPVASSFVCGSNGKTYTNECLLKVDSCAEQKEISVKHKGACD 1002 Score = 54.4 bits (125), Expect = 6e-08 Identities = 41/109 (37%), Positives = 51/109 (46%), Gaps = 19/109 (17%) Frame = -2 Query: 548 EYAPVCGSNGKTYANKCSL---EC----TQKIIPSLKMEH---------DGEC--QGAKL 423 E +PVCGS+GKTY N+C L C +II K G C A Sbjct: 516 EASPVCGSDGKTYENECKLRVESCKANQNVRIISRTKCNACTLSTCNLVYGTCSASSANA 575 Query: 422 ASLHPCICTREKGPVCGSDGVTYSNLC-LLKCASLSKPSLSIEHTGPCD 279 + + P C + PVCG DGVTY NLC LL+ A S + + G CD Sbjct: 576 SCICPTNCPSDWDPVCGDDGVTYQNLCHLLREACTSGRIIRRLYRGVCD 624 Score = 50.8 bits (116), Expect = 7e-07 Identities = 39/108 (36%), Positives = 51/108 (47%), Gaps = 19/108 (17%) Frame = -2 Query: 545 YAPVCGSNGKTYANKCSL--ECTQKIIPSLKMEHDGECQGAKLAS--LHPCI-------- 402 Y PVCGSN KTY N CSL E +K +P +KM + G C A C+ Sbjct: 1830 YDPVCGSNRKTYLNFCSLTAEACKKNLP-IKMAYKGRCCCASTTCGFYSNCVERPNGQAI 1888 Query: 401 ------CTREKGPVCGSDGVTYSNLCLLKCASLS-KPSLSIEHTGPCD 279 CT VCGS+G TY N CLL+ S + ++ + G C+ Sbjct: 1889 CVCDEKCTFAFDAVCGSNGRTYINDCLLRSDSCKLRKTIVVLQKGACN 1936 Score = 48.0 bits (109), Expect = 5e-06 Identities = 31/91 (34%), Positives = 46/91 (50%), Gaps = 4/91 (4%) Frame = -2 Query: 542 APVCGSNGKTYANKCSLE---CTQKIIPSLKMEHDGECQGAKLASLHPCICTREKGPVCG 372 A VCG++G+TY N S E C+ ++ L+ C +AS C + PVCG Sbjct: 773 ASVCGTDGETYENMYSCEHVDCSGNLVCKLE-NSKAVCTCPDVAS-----CDKMPDPVCG 826 Query: 371 SDGVTYSNLCLLKCAS-LSKPSLSIEHTGPC 282 +D Y+N CLL A+ + L + + GPC Sbjct: 827 TDNKEYANECLLNVAACAANIHLRVLNKGPC 857 Score = 48.0 bits (109), Expect = 5e-06 Identities = 34/90 (37%), Positives = 45/90 (50%), Gaps = 4/90 (4%) Frame = -2 Query: 536 VCGSNGKTYANKCSLE---CTQKIIPSLKMEHDGECQGAKLASLHPCICTREKGPVCGSD 366 VCGSNGKTY N+C L+ C ++ + ++H G C S H C E+ C D Sbjct: 968 VCGSNGKTYTNECLLKVDSCAEQ--KEISVKHKGACDA---CSNHVC----EENEDC--D 1016 Query: 365 GVTYSNLCLLK-CASLSKPSLSIEHTGPCD 279 TY + C +K A K SL + GPCD Sbjct: 1017 KKTYQSECHMKEEACTEKKSLHVLKGGPCD 1046 Score = 47.2 bits (107), Expect = 9e-06 Identities = 32/94 (34%), Positives = 45/94 (47%), Gaps = 19/94 (20%) Frame = -2 Query: 548 EYAPVCGSNGKTYANKCSLE---C-TQKIIPSL-----------KMEHDGEC----QGAK 426 ++ PVCGS+ +TY N C L+ C T + + L K +++ EC G+ Sbjct: 445 DFRPVCGSDLRTYVNLCRLQVEVCQTGRAVTVLRQGACDPCSVSKCKYNSECVKRADGST 504 Query: 425 LASLHPCICTREKGPVCGSDGVTYSNLCLLKCAS 324 C +E PVCGSDG TY N C L+ S Sbjct: 505 TCQCPTDRCPKEASPVCGSDGKTYENECKLRVES 538 Score = 45.6 bits (103), Expect = 3e-05 Identities = 38/111 (34%), Positives = 52/111 (46%), Gaps = 24/111 (21%) Frame = -2 Query: 539 PVCGSNGKTYANKCSLE---CTQKIIPSLKMEHDGECQGA-KLASLHP------------ 408 PVCG++ K YAN+C L C I L++ + G C G L H Sbjct: 823 PVCGTDNKEYANECLLNVAACAANI--HLRVLNKGPCGGGCALYKCHQFATCNEAPDKTP 880 Query: 407 -CICT-REK-----GPVCGSDGVTYSNLCLLKCASLS-KPSLSIEHTGPCD 279 C+C +EK PVC SDG TY N C+++ + S K S++ G CD Sbjct: 881 ICVCPDKEKCPSELRPVCASDGRTYVNECVMRALACSRKESVNKTKDGACD 931 Score = 45.6 bits (103), Expect = 3e-05 Identities = 35/106 (33%), Positives = 50/106 (47%), Gaps = 20/106 (18%) Frame = -2 Query: 539 PVCGSNGKTYANKCSLE---CTQKIIPSLKME-------HDGECQGAKLASLH-----PC 405 PVCGS+GK Y ++C LE C KI +LK + +C L C Sbjct: 1300 PVCGSDGKDYRSRCFLEVTSCALKIKITLKNNGLCVHPCNRTQCPSYSRCVLDSSLQAKC 1359 Query: 404 ICTR----EKGPVCGSDGVTYSNLCLLKCASL-SKPSLSIEHTGPC 282 +CT+ P+C S+G T+ N C L A+ + S++ HTG C Sbjct: 1360 VCTKSCPLSYEPLCASNGKTFPNQCALDMAACKANGSVTFLHTGFC 1405 Score = 45.6 bits (103), Expect = 3e-05 Identities = 36/108 (33%), Positives = 47/108 (43%), Gaps = 22/108 (20%) Frame = -2 Query: 539 PVCGSNGKTYANKCSLE---CTQKIIPSLKMEHDGECQGA--KLASLHPCICTREKG--- 384 PVCGS+GK+Y ++C L C KI L + G+C L LH C R Sbjct: 1692 PVCGSDGKSYGSECELRKEACEAKI--KLTLVSKGKCYDPCDDLQCLHGSTCVRRVNGSA 1749 Query: 383 -------------PVCGSDGVTYSNLCLLK-CASLSKPSLSIEHTGPC 282 PVCG DG +Y + C+LK A L ++I G C Sbjct: 1750 SCQCPECRTLKYTPVCGDDGKSYLSTCMLKRLACLKGVHIAIASKGRC 1797 Score = 44.4 bits (100), Expect = 6e-05 Identities = 28/106 (26%), Positives = 48/106 (45%), Gaps = 21/106 (19%) Frame = -2 Query: 536 VCGSNGKTYANKCSLECTQ-KIIPSLKMEHDGECQGAKLASLH-------------PCIC 399 VCGS+G +Y +C ++ T + + ++H G C S C+C Sbjct: 302 VCGSDGNSYFTECHMDATACRESRDITVKHKGPCGSCSPGSCKFYGVCVGVEDGSMKCVC 361 Query: 398 TREK------GPVCGSDGVTYSNLCLLK-CASLSKPSLSIEHTGPC 282 + + PVCG+D TY + C++K A K ++ ++H G C Sbjct: 362 PKPEECPYVNAPVCGTDDRTYPSECIMKTSACADKKAVRVKHAGEC 407 Score = 43.6 bits (98), Expect = 1e-04 Identities = 36/111 (32%), Positives = 49/111 (44%), Gaps = 21/111 (18%) Frame = -2 Query: 545 YAPVCGSNGKTYANKCSLECTQ-KIIPSLKMEHDGECQGAKLAS--LHP----------- 408 Y P+C SNGKT+ N+C+L+ K S+ H G C + H Sbjct: 1369 YEPLCASNGKTFPNQCALDMAACKANGSVTFLHTGFCTPCSTVTCLYHSKCFPQADGTGV 1428 Query: 407 CICTREKGP------VCGSDGVTYSNLCLLKCASL-SKPSLSIEHTGPCDN 276 CIC + P VCGSD VTY + C LK S + +++ G C N Sbjct: 1429 CICLDQCPPDNQNASVCGSDLVTYRSECELKAKSCNAMRNVTTLFKGECAN 1479 Score = 42.7 bits (96), Expect = 2e-04 Identities = 34/114 (29%), Positives = 55/114 (48%), Gaps = 26/114 (22%) Frame = -2 Query: 542 APVCGSNGKTYANKCSLE---CTQKIIPSLKMEHDGEC------------------QGAK 426 APVCG++ +TY ++C ++ C K +++++H GEC QG Sbjct: 372 APVCGTDDRTYPSECIMKTSACADK--KAVRVKHAGECGPCGTLVCTNGKNCVTSHQGLT 429 Query: 425 LASLHPC----ICTREKGPVCGSDGVTYSNLCLLKC-ASLSKPSLSIEHTGPCD 279 ++ C C R+ PVCGSD TY NLC L+ + ++++ G CD Sbjct: 430 RQAVCACPRFEDCPRDFRPVCGSDLRTYVNLCRLQVEVCQTGRAVTVLRQGACD 483 Score = 42.7 bits (96), Expect = 2e-04 Identities = 33/112 (29%), Positives = 49/112 (43%), Gaps = 24/112 (21%) Frame = -2 Query: 539 PVCGSNGKTYANKC---SLECTQKIIPSLKMEHDGECQGAKLASLH----PCI------- 402 PVCGS+ +Y NKC +L C + + ++H+G C +LA H C+ Sbjct: 1156 PVCGSDKVSYRNKCYMIALNCPKN--KYVYVKHEGYCAPCRLAECHKVYAKCVTTLYQTA 1213 Query: 401 ---------CTREKGPVCGSDGVTYSNLCLLKC-ASLSKPSLSIEHTGPCDN 276 C KG VC SD TY + C ++ A + +L + G C N Sbjct: 1214 RCVCPTLQECAARKGAVCASDMKTYQSECHMRVEACRANKALQVVRRGQCAN 1265 Score = 41.1 bits (92), Expect = 6e-04 Identities = 30/108 (27%), Positives = 47/108 (43%), Gaps = 19/108 (17%) Frame = -2 Query: 548 EYAPVCGSNGKTYANKCSLE---CTQKI-----------IPSLKMEHDGECQ----GAKL 423 +Y PVCG +GK+Y + C L+ C + + S + G C+ G ++ Sbjct: 1760 KYTPVCGDDGKSYLSTCMLKRLACLKGVHIAIASKGRCPCKSATCQFGGRCEIQEDGTEV 1819 Query: 422 ASLHPCICTREKGPVCGSDGVTYSNLCLLKCASLSKP-SLSIEHTGPC 282 + P C PVCGS+ TY N C L + K + + + G C Sbjct: 1820 C-ICPTYCRLNYDPVCGSNRKTYLNFCSLTAEACKKNLPIKMAYKGRC 1866 Score = 40.7 bits (91), Expect = 8e-04 Identities = 32/109 (29%), Positives = 48/109 (44%), Gaps = 23/109 (21%) Frame = -2 Query: 539 PVCGSNGKTYANKCSLE---CTQKIIPSLKMEHDGECQGAKLAS------------LHP- 408 PVC + G+T+ KC +E CT+ S+ + GEC + P Sbjct: 156 PVCSTTGETFITKCHMEVEACTES--RSMMVARRGECDPCSRVKCKEDRHCVVDMDMKPK 213 Query: 407 CICTREK------GPVCGSDGVTYSNLCLLKCASLSK-PSLSIEHTGPC 282 CIC E VCG+D +Y N C++K + K S+++ H G C Sbjct: 214 CICPSESECPLTVDTVCGTDKSSYLNECVMKARACRKEKSVTVAHRGFC 262 Score = 40.3 bits (90), Expect = 0.001 Identities = 34/109 (31%), Positives = 51/109 (46%), Gaps = 24/109 (22%) Frame = -2 Query: 536 VCGSNGKTYANKCSLECTQ-KIIPSLKMEHDGEC--------------QG-AKLASLHP- 408 VC S+GKTYA++C ++ P L++ +GEC G +S P Sbjct: 1082 VCASDGKTYASECHVKVRNCGRYPKLRVIFEGECGQIADPCSTVQCPNNGRCDASSGSPV 1141 Query: 407 CICTREKG------PVCGSDGVTYSNLCLLKCASLSKPS-LSIEHTGPC 282 C+C R + PVCGSD V+Y N C + + K + ++H G C Sbjct: 1142 CLCPRLEDCSDLNTPVCGSDKVSYRNKCYMIALNCPKNKYVYVKHEGYC 1190 Score = 40.3 bits (90), Expect = 0.001 Identities = 34/110 (30%), Positives = 53/110 (48%), Gaps = 21/110 (19%) Frame = -2 Query: 545 YAPVCGSNGKTYANKCSLECTQKIIPS-LKMEHDGEC-QGAKLASLHP----CI------ 402 Y PVCG++ +T+ N C L+ I S L + + G C LA P C+ Sbjct: 1546 YKPVCGTDMETHINACLLKLKSCQIESDLDVAYSGPCLPDPCLAKRCPPYAQCVPDHVLK 1605 Query: 401 --CT-REKGP-----VCGSDGVTYSNLCLLKC-ASLSKPSLSIEHTGPCD 279 CT E+ P +CGSDGV+Y + C ++ A ++++ H G C+ Sbjct: 1606 ARCTCPERCPLTYNLICGSDGVSYLSACAMRATACQQNRNITVAHHGACE 1655 Score = 40.3 bits (90), Expect = 0.001 Identities = 31/109 (28%), Positives = 50/109 (45%), Gaps = 21/109 (19%) Frame = -2 Query: 545 YAPVCGSNGKTYANKCSLECTQ-KIIPSLKMEHDGECQGAKLASLH-----PCICTREKG 384 Y +CGS+G +Y + C++ T + ++ + H G C+ ++ CI +E G Sbjct: 1618 YNLICGSDGVSYLSACAMRATACQQNRNITVAHHGACERVSCGNIRCPRFSMCISAQEGG 1677 Query: 383 --------------PVCGSDGVTYSNLC-LLKCASLSKPSLSIEHTGPC 282 PVCGSDG +Y + C L K A +K L++ G C Sbjct: 1678 IKCSCPIYCPPSGQPVCGSDGKSYGSECELRKEACEAKIKLTLVSKGKC 1726 Score = 39.1 bits (87), Expect = 0.002 Identities = 23/69 (33%), Positives = 36/69 (52%), Gaps = 7/69 (10%) Frame = -2 Query: 467 SLKMEHDGECQGAKLASLHPCICTREKG------PVCGSDGVTYSNLCLLKCASLS-KPS 309 S+K E G C + A + C+C R + PVCGSDG Y + C L+ S + K Sbjct: 1268 SVKCEFYGRC--VESAGVTKCVCPRSQECSDVIEPVCGSDGKDYRSRCFLEVTSCALKIK 1325 Query: 308 LSIEHTGPC 282 +++++ G C Sbjct: 1326 ITLKNNGLC 1334 Score = 37.5 bits (83), Expect = 0.007 Identities = 25/72 (34%), Positives = 32/72 (44%) Frame = -2 Query: 548 EYAPVCGSNGKTYANKCSLECTQKIIPSLKMEHDGECQGAKLASLHPCICTREKGPVCGS 369 ++ PVCG +G TY N C L + G + L+ +C PVC S Sbjct: 586 DWDPVCGDDGVTYQNLCHLL------------REACTSGRIIRRLYRGVCD----PVCAS 629 Query: 368 DGVTYSNLCLLK 333 DG TY N CL K Sbjct: 630 DGRTYQNECLAK 641 Score = 35.5 bits (78), Expect = 0.029 Identities = 32/109 (29%), Positives = 46/109 (42%), Gaps = 22/109 (20%) Frame = -2 Query: 539 PVCGSNGKTYANKCSLE---CTQKIIPSLKMEHDGEC-QGAKLASLHP-----------C 405 PVC + G+T+ KC +E CT+ S+ + GEC A L P C Sbjct: 85 PVCSTTGETFITKCHMEVEACTES--RSMMVARRGECGPCASLRCKSPSRCQVIKGKPQC 142 Query: 404 IC--TRE----KGPVCGSDGVTYSNLCLLKC-ASLSKPSLSIEHTGPCD 279 +C RE PVC + G T+ C ++ A S+ + G CD Sbjct: 143 VCRDVRECPSSMDPVCSTTGETFITKCHMEVEACTESRSMMVARRGECD 191 Score = 35.5 bits (78), Expect = 0.029 Identities = 30/107 (28%), Positives = 47/107 (43%), Gaps = 22/107 (20%) Frame = -2 Query: 536 VCGSNGKTYANKCSLECTQ-KIIPSLKMEHDGECQGAKLASL--H------------PCI 402 VCG++ +Y N+C ++ + S+ + H G C LA H C Sbjct: 229 VCGTDKSSYLNECVMKARACRKEKSVTVAHRGFCGACSLAKPCEHRAKCISNTDGTLTCT 288 Query: 401 CTREKG-P-----VCGSDGVTYSNLCLLKC-ASLSKPSLSIEHTGPC 282 C +E+ P VCGSDG +Y C + A ++++H GPC Sbjct: 289 CRKEENCPGRADYVCGSDGNSYFTECHMDATACRESRDITVKHKGPC 335 Score = 29.9 bits (64), Expect = 1.4 Identities = 29/100 (29%), Positives = 44/100 (44%), Gaps = 21/100 (21%) Frame = -2 Query: 518 KTYANKCSLE---CTQKIIPSLKMEHDGECQGAKLASLHP------------CIC-TREK 387 KTY ++C ++ CT+K SL + G C L C+C T ++ Sbjct: 1018 KTYQSECHMKEEACTEK--KSLHVLKGGPCDPCALRRCFAEQTCVISNGKAECVCPTVDQ 1075 Query: 386 GP----VCGSDGVTYSNLCLLKCASLSK-PSLSIEHTGPC 282 P VC SDG TY++ C +K + + P L + G C Sbjct: 1076 CPSGSTVCASDGKTYASECHVKVRNCGRYPKLRVIFEGEC 1115 >SB_41491| Best HMM Match : Kazal_1 (HMM E-Value=1.1e-12) Length = 77 Score = 55.6 bits (128), Expect = 3e-08 Identities = 22/43 (51%), Positives = 27/43 (62%) Frame = -2 Query: 410 PCICTREKGPVCGSDGVTYSNLCLLKCASLSKPSLSIEHTGPC 282 P +CT + PVCGSDG TY N+C LK A P L ++H G C Sbjct: 29 PTLCTLQYDPVCGSDGKTYGNMCFLKAAIKCNPDLYMKHKGAC 71 Score = 49.2 bits (112), Expect = 2e-06 Identities = 20/37 (54%), Positives = 24/37 (64%) Frame = -2 Query: 548 EYAPVCGSNGKTYANKCSLECTQKIIPSLKMEHDGEC 438 +Y PVCGS+GKTY N C L+ K P L M+H G C Sbjct: 35 QYDPVCGSDGKTYGNMCFLKAAIKCNPDLYMKHKGAC 71 >SB_6080| Best HMM Match : No HMM Matches (HMM E-Value=.) Length = 2101 Score = 55.6 bits (128), Expect = 3e-08 Identities = 32/101 (31%), Positives = 49/101 (48%), Gaps = 20/101 (19%) Frame = -2 Query: 548 EYAPVCGSNGKTYANKCSLECTQKIIPSL-KMEHDGECQ-----GAKLASLH-------- 411 EY PVCG++GKTY NKC + + + ++ + + GEC+ G + + Sbjct: 1302 EYMPVCGTDGKTYGNKCEMRASACLKSTMVTVAYPGECESNDPCGKRRCGFYAQCEVVNG 1361 Query: 410 ------PCICTREKGPVCGSDGVTYSNLCLLKCASLSKPSL 306 P IC PVCGSDG YSN C ++ A+ + + Sbjct: 1362 SAQCVCPSICPLHYSPVCGSDGNMYSNECAMRAAACKQQKM 1402 Score = 55.6 bits (128), Expect = 3e-08 Identities = 32/94 (34%), Positives = 44/94 (46%), Gaps = 7/94 (7%) Frame = -2 Query: 542 APVCGSNGKTYANKCSLE---CTQKIIPSLKMEHDGEC---QGAKLASLHPCICTREKGP 381 +PVCGS+GK Y + C L C + I ++ C G+ P CT + P Sbjct: 1764 SPVCGSDGKIYKDDCELRKTACESRRILLWQIRTLVTCINMNGSAACVCQPRPCTADYSP 1823 Query: 380 VCGSDGVTYSNLCLLKCASLSKP-SLSIEHTGPC 282 VC SDG TY N+C + A K +L + G C Sbjct: 1824 VCASDGQTYPNVCTMDSAGCQKSMNLKVVRNGTC 1857 Score = 55.2 bits (127), Expect = 3e-08 Identities = 40/114 (35%), Positives = 56/114 (49%), Gaps = 23/114 (20%) Frame = -2 Query: 545 YAPVCGSNGKTYANKCSLE---CTQK--IIPSL--KMEHDGECQGAKLA-SLHPCI---- 402 Y+PVCGS+G Y+N+C++ C Q+ I PSL K + D C + L CI Sbjct: 1375 YSPVCGSDGNMYSNECAMRAAACKQQKMITPSLPSKCKLDDPCDVTLCSHPLQKCILVSG 1434 Query: 401 ----------CTREKGPVCGSDGVTYSNLC-LLKCASLSKPSLSIEHTGPCDNN 273 C+ + VCGSD +TYSN C L + A +L++ GPC N Sbjct: 1435 VPRCECPMFKCSANRSDVCGSDRMTYSNECTLTQTACQESKNLTVVSQGPCPPN 1488 Score = 46.4 bits (105), Expect = 2e-05 Identities = 29/95 (30%), Positives = 45/95 (47%), Gaps = 8/95 (8%) Frame = -2 Query: 533 CGSNGKTYANKCSLECTQ--KIIP--SLKMEHDGECQGAKLASLH---PCICTREKGPVC 375 C K N C +C + K P ++ ++ +CQ S P CT E PVC Sbjct: 1248 CQMPQKCCFNGCHKDCVKPGKADPCDNVSCDYYAQCQVEDDGSTSCKCPIFCTYEYMPVC 1307 Query: 374 GSDGVTYSNLCLLKC-ASLSKPSLSIEHTGPCDNN 273 G+DG TY N C ++ A L +++ + G C++N Sbjct: 1308 GTDGKTYGNKCEMRASACLKSTMVTVAYPGECESN 1342 Score = 45.2 bits (102), Expect = 4e-05 Identities = 35/116 (30%), Positives = 54/116 (46%), Gaps = 27/116 (23%) Frame = -2 Query: 548 EYAPVCGSNGKTYANKCSLECT--QKIIPSLKMEHDGEC------------------QGA 429 +Y+PVC S+G+TY N C+++ QK + +LK+ +G C Q Sbjct: 1820 DYSPVCASDGQTYPNVCTMDSAGCQKSM-NLKVVRNGTCVRKEPKNPCGNIKCTHKQQQC 1878 Query: 428 KLASLHP---CI---CTREKGPVCGSDGVTYSNLCLLKCASLSK-PSLSIEHTGPC 282 + S P C+ C + VCGSDG TY N C LK + + + ++ G C Sbjct: 1879 VVRSGEPMCECVVNECPKNSSKVCGSDGWTYDNECFLKLYTCRQGKDVKVQQMGEC 1934 Score = 42.7 bits (96), Expect = 2e-04 Identities = 37/117 (31%), Positives = 53/117 (45%), Gaps = 28/117 (23%) Frame = -2 Query: 548 EYAPVCGSNGKTYANKCSLE---CTQKIIPSLKMEHDGECQGAKLASLHPC---ICTREK 387 +Y PVC S+GKTY N+ S+E C + +I L++ GEC A + PC +C + K Sbjct: 1530 DYTPVCASDGKTYPNRMSMENAGCEKNMI--LRIVSQGECPKA----VDPCEITLCDKGK 1583 Query: 386 ---------------------GPVCGSDGVTYSNLCLLKC-ASLSKPSLSIEHTGPC 282 PVC S+G TYSN C + A + L++ G C Sbjct: 1584 RCLLVNGTATCECFSACPDIYDPVCASNGKTYSNRCDMDADACIRDTKLTVVSQGAC 1640 Score = 35.1 bits (77), Expect = 0.038 Identities = 20/51 (39%), Positives = 28/51 (54%), Gaps = 4/51 (7%) Frame = -2 Query: 536 VCGSNGKTYANKCSLEC-TQKIIPSLKMEHDGECQGAKLASLHPC---ICT 396 VCGS+G TY N+C L+ T + +K++ GEC S PC +CT Sbjct: 1901 VCGSDGWTYDNECFLKLYTCRQGKDVKVQQMGECPAKISVSQDPCDISLCT 1951 Score = 32.7 bits (71), Expect = 0.20 Identities = 14/34 (41%), Positives = 18/34 (52%) Frame = -2 Query: 434 GAKLASLHPCICTREKGPVCGSDGVTYSNLCLLK 333 G + P IC+ PVCGSDG Y + C L+ Sbjct: 1748 GVAVCKCPPSICSPVISPVCGSDGKIYKDDCELR 1781 Score = 32.3 bits (70), Expect = 0.27 Identities = 26/105 (24%), Positives = 48/105 (45%), Gaps = 8/105 (7%) Frame = -2 Query: 524 NGKTYANKCSLECTQKIIPSLKMEHDGE-CQGAKLASLHPCICTRE-KGP-----VCGSD 366 N K A EC +++ S + G+ C K + C C + P +CG+D Sbjct: 10 NPKPSALSTISECEKELCASKRCPLQGQICVMDKHFNTAKCKCPQGCPAPNGDETICGTD 69 Query: 365 GVTYSNLCLLK-CASLSKPSLSIEHTGPCDNNRV*AVGN*NHSNK 234 G++Y + C + A + +++E+ G C N+R + +H N+ Sbjct: 70 GISYPSPCEMNLTACVLGDRIAVEYKGRCRNDRNLVKVSPSHQNQ 114 Score = 31.1 bits (67), Expect = 0.62 Identities = 11/20 (55%), Positives = 15/20 (75%) Frame = -2 Query: 548 EYAPVCGSNGKTYANKCSLE 489 EY PVC S+GK Y N+ ++E Sbjct: 1976 EYRPVCASDGKIYPNRMTME 1995 Score = 30.7 bits (66), Expect = 0.82 Identities = 37/116 (31%), Positives = 48/116 (41%), Gaps = 31/116 (26%) Frame = -2 Query: 536 VCGSNGKTYANKCSLECTQ-KIIPSLKMEHDGECQ-GAKLAS---LHPC----------- 405 VCGS+ TY+N+C+L T + +L + G C KLAS L PC Sbjct: 1452 VCGSDRMTYSNECTLTQTACQESKNLTVVSQGPCPPNPKLASGQPLDPCEISLCSHPQHT 1511 Query: 404 --------IC------TREKGPVCGSDGVTYSNLCLLKCASLSKPS-LSIEHTGPC 282 +C T + PVC SDG TY N ++ A K L I G C Sbjct: 1512 CHNIDNTAVCKCRQMMTADYTPVCASDGKTYPNRMSMENAGCEKNMILRIVSQGEC 1567 >SB_15403| Best HMM Match : CH (HMM E-Value=0) Length = 1907 Score = 51.2 bits (117), Expect = 5e-07 Identities = 37/113 (32%), Positives = 50/113 (44%), Gaps = 25/113 (22%) Frame = -2 Query: 545 YAPVCGSNGKTYANKCSLE---CTQKIIPSLKMEHDGECQ-------------------- 435 Y P+CG++GKTY N LE C Q+ S+ H G C Sbjct: 1243 YDPICGTDGKTYNNDKDLESAACAQQT--SIVRWHKGPCTVEPSCANLQCKYYSYCIVRD 1300 Query: 434 -GAKLASLHPCICTREKGPVCGSDGVTYSNLCLLKCASLSK-PSLSIEHTGPC 282 GA P C K VCG+DG+TY NLC L+ S + +++ H+G C Sbjct: 1301 GGAVCTCPDPAACPLVKSRVCGTDGITYDNLCRLRAESCRRYQPVNVLHSGYC 1353 Score = 49.6 bits (113), Expect = 2e-06 Identities = 29/62 (46%), Positives = 35/62 (56%), Gaps = 4/62 (6%) Frame = -2 Query: 455 EHDGECQ-GA--KLASLHPCICTREKGPVCGSDGVTYSNLCLLKCASL-SKPSLSIEHTG 288 ++ G CQ GA K + CTRE PVCGSDG TY+NLCLL A S+ + H G Sbjct: 707 KYGGVCQAGADGKTKCVCSAACTREYAPVCGSDGNTYNNLCLLTAARCQSQTFIYRAHFG 766 Query: 287 PC 282 C Sbjct: 767 TC 768 Score = 38.3 bits (85), Expect = 0.004 Identities = 23/58 (39%), Positives = 29/58 (50%), Gaps = 5/58 (8%) Frame = -2 Query: 440 CQGAKLASLHPCICTRE----KGPVCGSDGVTYSNLCLLKCASLS-KPSLSIEHTGPC 282 C + S H C C R PVCG DG TY N CLL+ S S + S++ + G C Sbjct: 960 CVPSADGSGHICECPRSCPSVNYPVCGDDGQTYDNECLLQLESCSRRRSITTVNYGSC 1017 Score = 36.3 bits (80), Expect = 0.017 Identities = 18/46 (39%), Positives = 23/46 (50%), Gaps = 1/46 (2%) Frame = -2 Query: 548 EYAPVCGSNGKTYANKCSLECTQ-KIIPSLKMEHDGECQGAKLASL 414 EYAPVCGS+G TY N C L + + + H G C A + Sbjct: 731 EYAPVCGSDGNTYNNLCLLTAARCQSQTFIYRAHFGTCGSTSCAEI 776 Score = 33.1 bits (72), Expect = 0.15 Identities = 20/60 (33%), Positives = 33/60 (55%), Gaps = 4/60 (6%) Frame = -2 Query: 449 DGEC-QGAKLASLHPCICTREKG--PVCGSDGVTYSNLCLLKCASLSKPSLSIE-HTGPC 282 +G+C QGA + C + P+CG+DG TY+N L+ A+ ++ + + H GPC Sbjct: 1220 NGQCVQGADNYARCECDLRPDPAYDPICGTDGKTYNNDKDLESAACAQQTSIVRWHKGPC 1279 Score = 32.3 bits (70), Expect = 0.27 Identities = 15/42 (35%), Positives = 23/42 (54%), Gaps = 2/42 (4%) Frame = -2 Query: 401 CTREKGPVCGSDGVTYSNLCLLKCASLS--KPSLSIEHTGPC 282 C R VCGSD Y+N C+L+ + + L++ + GPC Sbjct: 1566 CPRSDQLVCGSDDRDYANECVLQARACTWRDSLLTVHNKGPC 1607 Score = 29.9 bits (64), Expect = 1.4 Identities = 10/17 (58%), Positives = 14/17 (82%) Frame = -2 Query: 539 PVCGSNGKTYANKCSLE 489 PVCG +G+TY N+C L+ Sbjct: 983 PVCGDDGQTYDNECLLQ 999 >SB_53017| Best HMM Match : Kazal_1 (HMM E-Value=0) Length = 1488 Score = 49.6 bits (113), Expect = 2e-06 Identities = 33/107 (30%), Positives = 49/107 (45%), Gaps = 19/107 (17%) Frame = -2 Query: 545 YAPVCGSNGKTYANKCSLE---C-TQKIIPSLKMEHDGECQGAKLASLHPCI-------- 402 + PVCG++G+ Y N+C L C TQ I K C+ + C+ Sbjct: 741 FKPVCGTDGREYLNRCFLRRNACRTQTSIKVHKWGLCNPCKNVECKFKARCVGLPDGSAV 800 Query: 401 ------CTREKGPVCGSDGVTYSNLCLLKC-ASLSKPSLSIEHTGPC 282 C E PVCG DG TYS+ C + A ++ S++++H G C Sbjct: 801 CECNTECPSEASPVCGQDGRTYSSTCAMDARACQAQTSIAVKHPGLC 847 Score = 47.2 bits (107), Expect = 9e-06 Identities = 33/109 (30%), Positives = 47/109 (43%), Gaps = 22/109 (20%) Frame = -2 Query: 539 PVCGSNGKTYANKCSLE-----------------CTQKIIPSLKMEHDGECQGAKLASLH 411 P+CGS+GK Y NKC +E C+ + H G C H Sbjct: 671 PLCGSDGKNYWNKCHIERESCRYNLDLKVKWQGFCSVSPCSRISCSHYGRCVVRNNGKAH 730 Query: 410 PCICTREKG----PVCGSDGVTYSNLCLL-KCASLSKPSLSIEHTGPCD 279 C+C R+ PVCG+DG Y N C L + A ++ S+ + G C+ Sbjct: 731 -CVCPRQCQVRFKPVCGTDGREYLNRCFLRRNACRTQTSIKVHKWGLCN 778 Score = 34.7 bits (76), Expect = 0.050 Identities = 13/39 (33%), Positives = 26/39 (66%), Gaps = 1/39 (2%) Frame = -2 Query: 548 EYAPVCGSNGKTYANKCSLECTQ-KIIPSLKMEHDGECQ 435 E +PVCG +G+TY++ C+++ + S+ ++H G C+ Sbjct: 810 EASPVCGQDGRTYSSTCAMDARACQAQTSIAVKHPGLCR 848 Score = 33.9 bits (74), Expect = 0.088 Identities = 16/44 (36%), Positives = 19/44 (43%), Gaps = 1/44 (2%) Frame = -2 Query: 410 PCICTREKGPVCGSDGVTYSNLCL-LKCASLSKPSLSIEHTGPC 282 P C+ PVCG D TY N C + A K + GPC Sbjct: 253 PSDCSHTYSPVCGGDKTTYINNCTRIAAACNMKKDIPFNVNGPC 296 Score = 27.9 bits (59), Expect = 5.8 Identities = 9/17 (52%), Positives = 12/17 (70%) Frame = -2 Query: 545 YAPVCGSNGKTYANKCS 495 Y+PVCG + TY N C+ Sbjct: 260 YSPVCGGDKTTYINNCT 276 >SB_39831| Best HMM Match : Kazal_1 (HMM E-Value=2.4e-19) Length = 173 Score = 47.6 bits (108), Expect = 7e-06 Identities = 20/46 (43%), Positives = 32/46 (69%), Gaps = 1/46 (2%) Frame = -2 Query: 404 ICTREKGPVCGSDGVTYSNLCLLKCASL-SKPSLSIEHTGPCDNNR 270 IC + PVCGSD VTYSN C+L+ A+ S +++++H G C +++ Sbjct: 29 ICNKMYQPVCGSDNVTYSNPCMLRSATCKSNGTITMKHRGKCGSSQ 74 Score = 39.5 bits (88), Expect = 0.002 Identities = 19/52 (36%), Positives = 28/52 (53%), Gaps = 1/52 (1%) Frame = -2 Query: 545 YAPVCGSNGKTYANKCSL-ECTQKIIPSLKMEHDGECQGAKLASLHPCICTR 393 Y PVCGS+ TY+N C L T K ++ M+H G+C ++ C T+ Sbjct: 34 YQPVCGSDNVTYSNPCMLRSATCKSNGTITMKHRGKCGSSQSCEQKKCKGTK 85 >SB_135| Best HMM Match : Kazal_1 (HMM E-Value=2.9e-19) Length = 92 Score = 47.2 bits (107), Expect = 9e-06 Identities = 20/40 (50%), Positives = 28/40 (70%), Gaps = 1/40 (2%) Frame = -2 Query: 545 YAPVCGSNGKTYANKCSLE-CTQKIIPSLKMEHDGECQGA 429 Y PVCG++GKTY NKC LE T + ++++ H+GEC A Sbjct: 47 YRPVCGTDGKTYGNKCVLEIATCESEGAVQLAHEGECDSA 86 Score = 45.6 bits (103), Expect = 3e-05 Identities = 19/43 (44%), Positives = 29/43 (67%), Gaps = 1/43 (2%) Frame = -2 Query: 401 CTREKGPVCGSDGVTYSNLCLLKCASL-SKPSLSIEHTGPCDN 276 CT+ PVCG+DG TY N C+L+ A+ S+ ++ + H G CD+ Sbjct: 43 CTKIYRPVCGTDGKTYGNKCVLEIATCESEGAVQLAHEGECDS 85 >SB_11826| Best HMM Match : Kazal_1 (HMM E-Value=1.2e-16) Length = 98 Score = 47.2 bits (107), Expect = 9e-06 Identities = 19/37 (51%), Positives = 28/37 (75%), Gaps = 1/37 (2%) Frame = -2 Query: 545 YAPVCGSNGKTYANKCSLE-CTQKIIPSLKMEHDGEC 438 Y+P+CG++GKTY NKC LE T + ++K+ H+GEC Sbjct: 47 YSPMCGTDGKTYGNKCMLEIATCESEGAVKLAHEGEC 83 Score = 40.7 bits (91), Expect = 8e-04 Identities = 18/47 (38%), Positives = 28/47 (59%), Gaps = 5/47 (10%) Frame = -2 Query: 407 CICTRE----KGPVCGSDGVTYSNLCLLKCASL-SKPSLSIEHTGPC 282 C+C R P+CG+DG TY N C+L+ A+ S+ ++ + H G C Sbjct: 37 CVCNRACKKIYSPMCGTDGKTYGNKCMLEIATCESEGAVKLAHEGEC 83 >SB_44384| Best HMM Match : Kazal_1 (HMM E-Value=1.4e-21) Length = 85 Score = 46.0 bits (104), Expect = 2e-05 Identities = 20/42 (47%), Positives = 29/42 (69%), Gaps = 1/42 (2%) Frame = -2 Query: 404 ICTREKGPVCGSDGVTYSNLCLLKCASL-SKPSLSIEHTGPC 282 IC + PVCGSD VTYSN C+L+ A+ S +++++H G C Sbjct: 43 ICPKIYRPVCGSDNVTYSNPCMLRSATCKSNGTITMKHRGKC 84 Score = 37.9 bits (84), Expect = 0.005 Identities = 17/37 (45%), Positives = 23/37 (62%), Gaps = 1/37 (2%) Frame = -2 Query: 545 YAPVCGSNGKTYANKCSL-ECTQKIIPSLKMEHDGEC 438 Y PVCGS+ TY+N C L T K ++ M+H G+C Sbjct: 48 YRPVCGSDNVTYSNPCMLRSATCKSNGTITMKHRGKC 84 >SB_46203| Best HMM Match : No HMM Matches (HMM E-Value=.) Length = 557 Score = 45.2 bits (102), Expect = 4e-05 Identities = 30/86 (34%), Positives = 41/86 (47%), Gaps = 17/86 (19%) Frame = -2 Query: 539 PVCGSNGKTYANKCSLE---C-TQKIIPSLKMEHDGECQGAKLASLH-PCI--------- 402 PVCGSNGK Y N+C L+ C T +I + CQ + ++ + C+ Sbjct: 214 PVCGSNGKDYNNECELQQFACKTNTMITVARRSPCHPCQTSPCSAPYAKCLVVQGEAVCT 273 Query: 401 ---CTREKGPVCGSDGVTYSNLCLLK 333 C PVCGSDG Y N+C L+ Sbjct: 274 CLSCPNMLDPVCGSDGKNYDNVCKLR 299 Score = 41.5 bits (93), Expect = 4e-04 Identities = 39/111 (35%), Positives = 50/111 (45%), Gaps = 25/111 (22%) Frame = -2 Query: 539 PVCGSNGKTYANKCSLE---CTQK--IIPSLKMEHDGECQGA----------KLASLHP- 408 PV GS+GK Y N+C L+ C K I+ + + G C G K+ P Sbjct: 378 PVYGSDGKNYDNECLLKLAACKSKSRILIAGSGRYPGPCSGVTCDSPPYSTCKVQDDKPT 437 Query: 407 CICTRE----KGPVCGSDGVTYSNLCLLKCASL-SKPSLSI----EHTGPC 282 C+C PV GSDG Y N CLLK A+ SK + I + GPC Sbjct: 438 CVCVEPCPEILKPVYGSDGKDYDNECLLKLAACKSKSRILIAGFGRYPGPC 488 Score = 38.7 bits (86), Expect = 0.003 Identities = 34/97 (35%), Positives = 43/97 (44%), Gaps = 20/97 (20%) Frame = -2 Query: 539 PVCGSNGKTYANKCSLE---CTQK--IIPSLKMEHDGECQGA----------KLASLHP- 408 PV GS+GK Y N+C L+ C K I+ + + G C G K+ P Sbjct: 450 PVYGSDGKDYDNECLLKLAACKSKSRILIAGFGRYPGPCSGVTCDSPPYSTCKVQDDKPT 509 Query: 407 CICTRE----KGPVCGSDGVTYSNLCLLKCASLSKPS 309 C+C PV GSDG Y N CLLK A+ S Sbjct: 510 CVCVEPCPEILKPVYGSDGKDYDNECLLKLAACKSKS 546 Score = 34.7 bits (76), Expect = 0.050 Identities = 30/88 (34%), Positives = 42/88 (47%), Gaps = 6/88 (6%) Frame = -2 Query: 527 SNGKTYANKCS-LECTQKIIPSLKMEHDGECQGAKLASLHPCICTREKGPVCGSDGVTYS 351 ++G T A CS + C + K++ DG+ + PC + PV GSDG Y Sbjct: 335 TSGPTTAGPCSNVTCDSPPYSTCKVQ-DGK---PTCVCVEPC--PKILKPVYGSDGKNYD 388 Query: 350 NLCLLKCASL-SKPSLSI----EHTGPC 282 N CLLK A+ SK + I + GPC Sbjct: 389 NECLLKLAACKSKSRILIAGSGRYPGPC 416 Score = 34.3 bits (75), Expect = 0.067 Identities = 26/91 (28%), Positives = 42/91 (46%), Gaps = 5/91 (5%) Frame = -2 Query: 539 PVCGSNGKTYANKCSLE---C-TQKIIPSLKMEHDGECQGAKLASLHPCICTREKGPVCG 372 PVCGS+GK Y N+C+L C T +I ++ + A L++ P + K P Sbjct: 120 PVCGSDGKNYDNECNLRQNACKTNTLITVVRRD-------ACLSTARPVTTQQTKKPASS 172 Query: 371 SDGVTYSNLCLLK-CASLSKPSLSIEHTGPC 282 + T S+ C+ K C + +S+ C Sbjct: 173 AFVPTTSDPCMTKACTAPYSKCMSVRGKAVC 203 Score = 33.5 bits (73), Expect = 0.12 Identities = 16/56 (28%), Positives = 29/56 (51%), Gaps = 2/56 (3%) Frame = -2 Query: 443 ECQGAKLASLHPCI-CTREKGPVCGSDGVTYSNLC-LLKCASLSKPSLSIEHTGPC 282 +C + ++ C+ C + PVCGS+G Y+N C L + A + +++ PC Sbjct: 193 KCMSVRGKAVCMCMSCPKMNKPVCGSNGKDYNNECELQQFACKTNTMITVARRSPC 248 Score = 29.9 bits (64), Expect = 1.4 Identities = 12/23 (52%), Positives = 13/23 (56%) Frame = -2 Query: 401 CTREKGPVCGSDGVTYSNLCLLK 333 C PVCGSDG Y N C L+ Sbjct: 114 CPNILDPVCGSDGKNYDNECNLR 136 >SB_40582| Best HMM Match : Kazal_1 (HMM E-Value=0) Length = 1568 Score = 45.2 bits (102), Expect = 4e-05 Identities = 37/104 (35%), Positives = 54/104 (51%), Gaps = 19/104 (18%) Frame = -2 Query: 536 VCGSNGKTYANKCSLE---CTQK---IIPSLKMEH--DG-ECQG--AKLASLH---PCIC 399 V GS+GK Y N+C L+ CT I+ + H +G EC A S+ C+C Sbjct: 1009 VRGSDGKIYDNECLLKLAACTTNKRIILEAFLGPHLCEGVECDAPYATCVSVDGTPTCVC 1068 Query: 398 TR----EKGPVCGSDGVTYSNLCLLKCASL-SKPSLSIEHTGPC 282 R + PVCGSDG TY+N CL++ AS + ++++ PC Sbjct: 1069 PRRCPKKLMPVCGSDGKTYNNECLMRAASCKANKNITVSSYFPC 1112 Score = 39.9 bits (89), Expect = 0.001 Identities = 39/111 (35%), Positives = 50/111 (45%), Gaps = 25/111 (22%) Frame = -2 Query: 539 PVCGSNGKTYANKCSLE---CTQK--IIPSLKMEHDGECQGA----------KLASLHP- 408 PV GS+GK Y N+C L+ C K I+ + + G C G K+ P Sbjct: 9 PVYGSDGKDYDNECLLKLAACKSKSRILIAGFGRYPGPCSGVTCDSPPYSTCKVQDDKPT 68 Query: 407 CICTRE----KGPVCGSDGVTYSNLCLLKCASL-SKPSLSI----EHTGPC 282 C+C PV GSDG Y N CLLK A+ SK + I + GPC Sbjct: 69 CVCVEPCPEILKPVYGSDGKDYDNECLLKLAACKSKSRILIAGFGRYPGPC 119 Score = 39.9 bits (89), Expect = 0.001 Identities = 39/111 (35%), Positives = 50/111 (45%), Gaps = 25/111 (22%) Frame = -2 Query: 539 PVCGSNGKTYANKCSLE---CTQK--IIPSLKMEHDGECQGA----------KLASLHP- 408 PV GS+GK Y N+C L+ C K I+ + + G C G K+ P Sbjct: 81 PVYGSDGKDYDNECLLKLAACKSKSRILIAGFGRYPGPCSGVTCDSPPYSTCKVQDDKPT 140 Query: 407 CICTRE----KGPVCGSDGVTYSNLCLLKCASL-SKPSLSI----EHTGPC 282 C+C PV GSDG Y N CLLK A+ SK + I + GPC Sbjct: 141 CVCVEPCPEILKPVYGSDGKDYDNECLLKLAACKSKSRILIAGFGRYPGPC 191 Score = 39.9 bits (89), Expect = 0.001 Identities = 18/35 (51%), Positives = 21/35 (60%) Frame = -2 Query: 437 QGAKLASLHPCICTREKGPVCGSDGVTYSNLCLLK 333 Q K + P C E PVCG+DGVTY NLC L+ Sbjct: 590 QDGKPVCVCPPGCPSEVKPVCGTDGVTYDNLCSLR 624 Score = 39.1 bits (87), Expect = 0.002 Identities = 40/112 (35%), Positives = 49/112 (43%), Gaps = 24/112 (21%) Frame = -2 Query: 539 PVCGSNGKTYANKCSLE---CTQK--IIPSLKMEHDGECQGA----------KLASLHP- 408 PV GS+GK Y N+C L+ C K I+ + + G C G K+ P Sbjct: 153 PVYGSDGKDYDNECLLKLAACKSKSRILIAGFGRYPGPCSGVTCDSPPYSTCKVQDDKPT 212 Query: 407 CICTRE----KGPVCGSDGVTYSNLCLLK-CASLSKPSLSIEHTG---PCDN 276 C+C PV GSDG Y N CLLK A SK + I G PC N Sbjct: 213 CVCVEPCPEILKPVYGSDGKDYDNECLLKLSACKSKSRILIAGFGRYHPCTN 264 Score = 36.7 bits (81), Expect = 0.012 Identities = 34/104 (32%), Positives = 45/104 (43%), Gaps = 18/104 (17%) Frame = -2 Query: 539 PVCGSNGKTYANKCSLE---CTQK---IIPSLKMEH---DGECQGAK---LASLHPCICT 396 PV GS+GK Y N+C L+ C K +I H + C LA ICT Sbjct: 225 PVYGSDGKDYDNECLLKLSACKSKSRILIAGFGRYHPCTNAVCTAPFAICLAVEREAICT 284 Query: 395 REKGP-----VCGSDGVTYSNLCLL-KCASLSKPSLSIEHTGPC 282 P VCGSDG Y + C L + A + +++ GPC Sbjct: 285 CRSCPLINIPVCGSDGAQYDSECALQQQACQTDTDITVISEGPC 328 Score = 35.5 bits (78), Expect = 0.029 Identities = 33/94 (35%), Positives = 43/94 (45%), Gaps = 20/94 (21%) Frame = -2 Query: 545 YAPVCGSNGKTYANKCSLE---CT--QKII--------PSLKMEHDGE----CQ---GAK 426 Y PV GS+GK Y N+C L+ CT ++II P D C+ K Sbjct: 1381 YDPVYGSDGKNYDNECELKRAACTTNKRIILAGRGRVHPCAGFSCDSPPYSTCKVQDDGK 1440 Query: 425 LASLHPCICTREKGPVCGSDGVTYSNLCLLKCAS 324 + + P C + PV GSDG Y N C LK A+ Sbjct: 1441 PSCVCPPKCEKVYDPVYGSDGKNYDNECELKRAA 1474 Score = 33.5 bits (73), Expect = 0.12 Identities = 31/94 (32%), Positives = 41/94 (43%), Gaps = 20/94 (21%) Frame = -2 Query: 545 YAPVCGSNGKTYANKCSLE---CTQ----------KIIPSLKMEHD----GECQ---GAK 426 Y PV GS+GK Y N+C L+ CT ++ P D C+ K Sbjct: 447 YDPVYGSDGKNYDNECELKRAACTSNRRIILAGRGRVHPCAGFNCDSPPYSTCKVQDNGK 506 Query: 425 LASLHPCICTREKGPVCGSDGVTYSNLCLLKCAS 324 A + C++ V GSDG Y N CLLK A+ Sbjct: 507 PACVCQSGCSKILKRVRGSDGKIYDNECLLKLAA 540 Score = 32.3 bits (70), Expect = 0.27 Identities = 20/45 (44%), Positives = 23/45 (51%), Gaps = 5/45 (11%) Frame = -2 Query: 401 CTREKGPVCGSDGVTYSNLCLLKCASL-SKPSLSI----EHTGPC 282 C PV GSDG Y N CLLK A+ SK + I + GPC Sbjct: 3 CPEILKPVYGSDGKDYDNECLLKLAACKSKSRILIAGFGRYPGPC 47 Score = 31.9 bits (69), Expect(2) = 4e-04 Identities = 22/65 (33%), Positives = 30/65 (46%), Gaps = 1/65 (1%) Frame = -2 Query: 515 TYANKCS-LECTQKIIPSLKMEHDGECQGAKLASLHPCICTREKGPVCGSDGVTYSNLCL 339 T + C+ C + K++ DG K A + P C + PV GSDG Y N C Sbjct: 409 TTPDPCAGFSCDSPPFSTCKVQDDG-----KPACVCPPQCEKVYDPVYGSDGKNYDNECE 463 Query: 338 LKCAS 324 LK A+ Sbjct: 464 LKRAA 468 Score = 31.9 bits (69), Expect = 0.36 Identities = 22/65 (33%), Positives = 31/65 (47%), Gaps = 1/65 (1%) Frame = -2 Query: 515 TYANKCS-LECTQKIIPSLKMEHDGECQGAKLASLHPCICTREKGPVCGSDGVTYSNLCL 339 T A+ C+ C + +++ DG K A + P C + PV GSDG Y N C Sbjct: 1343 TTADPCAGFNCDSPPYSTCEVQDDG-----KPACVCPPKCEKVYDPVYGSDGKNYDNECE 1397 Query: 338 LKCAS 324 LK A+ Sbjct: 1398 LKRAA 1402 Score = 31.5 bits (68), Expect = 0.47 Identities = 20/55 (36%), Positives = 26/55 (47%) Frame = -2 Query: 488 CTQKIIPSLKMEHDGECQGAKLASLHPCICTREKGPVCGSDGVTYSNLCLLKCAS 324 C + K++ DG K A + P C + PV GSDG Y N C LK A+ Sbjct: 337 CDSPPFSTCKVQDDG-----KPACVCPPKCEKVYDPVYGSDGKNYDNECELKRAA 386 Score = 31.5 bits (68), Expect = 0.47 Identities = 11/14 (78%), Positives = 13/14 (92%) Frame = -2 Query: 539 PVCGSNGKTYANKC 498 PVCGS+GKTY N+C Sbjct: 1078 PVCGSDGKTYNNEC 1091 Score = 31.1 bits (67), Expect = 0.62 Identities = 17/40 (42%), Positives = 21/40 (52%), Gaps = 3/40 (7%) Frame = -2 Query: 548 EYAPVCGSNGKTYANKCSLE---CTQKIIPSLKMEHDGEC 438 E PVCG++G TY N CSL CT + + GEC Sbjct: 605 EVKPVCGTDGVTYDNLCSLRLKACTDN--TRTRFKAFGEC 642 Score = 30.3 bits (65), Expect = 1.1 Identities = 16/35 (45%), Positives = 19/35 (54%) Frame = -2 Query: 428 KLASLHPCICTREKGPVCGSDGVTYSNLCLLKCAS 324 K A + P C + PV GSDG Y N C LK A+ Sbjct: 755 KPACVCPPKCEKVYDPVYGSDGKNYDNECELKRAA 789 Score = 30.3 bits (65), Expect = 1.1 Identities = 16/35 (45%), Positives = 19/35 (54%) Frame = -2 Query: 428 KLASLHPCICTREKGPVCGSDGVTYSNLCLLKCAS 324 K A + P C + PV GSDG Y N C LK A+ Sbjct: 874 KPACVCPPKCEKVYDPVYGSDGKNYDNECELKRAA 908 Score = 30.3 bits (65), Expect = 1.1 Identities = 21/65 (32%), Positives = 30/65 (46%), Gaps = 1/65 (1%) Frame = -2 Query: 515 TYANKCS-LECTQKIIPSLKMEHDGECQGAKLASLHPCICTREKGPVCGSDGVTYSNLCL 339 T + C+ C + K++ DG K + + P C + PV GSDG Y N C Sbjct: 1497 TTPDPCAGFSCDSPPYSTCKVQDDG-----KPSCVCPPKCEKVYDPVYGSDGKNYDNECE 1551 Query: 338 LKCAS 324 LK A+ Sbjct: 1552 LKRAA 1556 Score = 29.1 bits (62), Expect(2) = 4e-04 Identities = 11/19 (57%), Positives = 14/19 (73%) Frame = -2 Query: 545 YAPVCGSNGKTYANKCSLE 489 Y PV GS+GK Y N+C L+ Sbjct: 365 YDPVYGSDGKNYDNECELK 383 Score = 29.1 bits (62), Expect = 2.5 Identities = 11/19 (57%), Positives = 14/19 (73%) Frame = -2 Query: 545 YAPVCGSNGKTYANKCSLE 489 Y PV GS+GK Y N+C L+ Sbjct: 768 YDPVYGSDGKNYDNECELK 786 Score = 29.1 bits (62), Expect = 2.5 Identities = 11/19 (57%), Positives = 14/19 (73%) Frame = -2 Query: 545 YAPVCGSNGKTYANKCSLE 489 Y PV GS+GK Y N+C L+ Sbjct: 887 YDPVYGSDGKNYDNECELK 905 Score = 29.1 bits (62), Expect = 2.5 Identities = 11/19 (57%), Positives = 14/19 (73%) Frame = -2 Query: 545 YAPVCGSNGKTYANKCSLE 489 Y PV GS+GK Y N+C L+ Sbjct: 1535 YDPVYGSDGKNYDNECELK 1553 Score = 28.3 bits (60), Expect = 4.4 Identities = 20/55 (36%), Positives = 25/55 (45%) Frame = -2 Query: 488 CTQKIIPSLKMEHDGECQGAKLASLHPCICTREKGPVCGSDGVTYSNLCLLKCAS 324 C + K++ DG K A + P C V GSDG Y N CLLK A+ Sbjct: 668 CDTPPYSTCKVQDDG-----KPACVCPSKCPEILKRVRGSDGKIYDNECLLKQAA 717 Score = 27.9 bits (59), Expect = 5.8 Identities = 13/26 (50%), Positives = 16/26 (61%) Frame = -2 Query: 401 CTREKGPVCGSDGVTYSNLCLLKCAS 324 C++ V GSDG Y N CLLK A+ Sbjct: 1002 CSKILKRVRGSDGKIYDNECLLKLAA 1027 >SB_36847| Best HMM Match : No HMM Matches (HMM E-Value=.) Length = 344 Score = 44.8 bits (101), Expect = 5e-05 Identities = 26/62 (41%), Positives = 33/62 (53%), Gaps = 4/62 (6%) Frame = -2 Query: 452 HDG-ECQGAKLASLHPCI--CTREKGPVCGSDGVTYSNLC-LLKCASLSKPSLSIEHTGP 285 H G EC AK + C+ C PVCGSDGVTY N C L + A + ++I GP Sbjct: 65 HAGQECVAAKGKASCECLSECPDHIKPVCGSDGVTYPNHCELHRIACVHTKKITIRSKGP 124 Query: 284 CD 279 C+ Sbjct: 125 CE 126 Score = 29.9 bits (64), Expect = 1.4 Identities = 11/16 (68%), Positives = 12/16 (75%) Frame = -2 Query: 539 PVCGSNGKTYANKCSL 492 PVCGS+G TY N C L Sbjct: 91 PVCGSDGVTYPNHCEL 106 >SB_7591| Best HMM Match : No HMM Matches (HMM E-Value=.) Length = 3261 Score = 44.4 bits (100), Expect = 6e-05 Identities = 32/104 (30%), Positives = 47/104 (45%), Gaps = 18/104 (17%) Frame = -2 Query: 539 PVCGSNGKTYANKCSL-ECTQKIIPSLKMEHDGECQGAK----LASLHPC-------ICT 396 PVC S+ TY N+C++ + + L G+C A C +C Sbjct: 1590 PVCASDNNTYPNECAMKQLACQSAKVLTFRRKGDCDPCNDFDCTAPYSTCEAKDDKAVCV 1649 Query: 395 REKGP-----VCGSDGVTYSNLCLLKCASL-SKPSLSIEHTGPC 282 K P VCGSDG TY N C+L+ A+ S +L++ + G C Sbjct: 1650 CPKCPKIVKQVCGSDGKTYDNECVLRMAACESNRTLAVRNEGNC 1693 Score = 44.0 bits (99), Expect = 8e-05 Identities = 30/107 (28%), Positives = 48/107 (44%), Gaps = 20/107 (18%) Frame = -2 Query: 539 PVCGSNGKTYANKCSLE---CTQKIIPSLKME------HDGECQGAKLASLHP------C 405 PVCG++ TY N+C + C +++ + D C +S P C Sbjct: 1145 PVCGTDNNTYDNECLMRQQACVANATVAVRRKGHCDPCKDVNCTSPPYSSCRPLDNKPVC 1204 Query: 404 I----CTREKGPVCGSDGVTYSNLCLLK-CASLSKPSLSIEHTGPCD 279 C+ PVCGSD TY N CL++ A ++ ++++ G CD Sbjct: 1205 ACPENCSSTVDPVCGSDNNTYDNECLMRQQACVANTTVAVRRKGDCD 1251 Score = 44.0 bits (99), Expect = 8e-05 Identities = 36/110 (32%), Positives = 49/110 (44%), Gaps = 23/110 (20%) Frame = -2 Query: 536 VCGSNGKTYANKCSLE---CTQKIIPSLKMEHD-GECQGAKLASLHPCICTREKG----- 384 VCGS+GKTY N+C L C +++ E + G C+G S+ CT G Sbjct: 1660 VCGSDGKTYDNECVLRMAACESNRTLAVRNEGNCGLCEGFSCDSVPYSRCTIINGSPTCV 1719 Query: 383 ----------PVCGSDGVTYSNLCLLKCASLSKPSLSI----EHTGPCDN 276 PVCGSD +Y N+C L+ S + SL + PC N Sbjct: 1720 CPPSCPNTLDPVCGSDLQSYDNVCFLRMQSCQQISLITVLRPNYCDPCQN 1769 Score = 43.2 bits (97), Expect = 1e-04 Identities = 32/101 (31%), Positives = 45/101 (44%), Gaps = 15/101 (14%) Frame = -2 Query: 536 VCGSNGKTYANKCSLECTQKIIPSLKMEHD-------GECQGAKLAS-------LHPCIC 399 VCG++ TY N+C L+ Q P ++ D C A L L C Sbjct: 1455 VCGTDNITYNNECFLK-RQAARPIARLRSDERATVTRANCTNAPLLRTLFAKLWLTSQYC 1513 Query: 398 TREKGPVCGSDGVTYSNLCLLKC-ASLSKPSLSIEHTGPCD 279 VCG+D +TYSN CL+K A + +L ++ G CD Sbjct: 1514 PASLDLVCGTDNITYSNECLMKYQACRTNSALKVKRKGDCD 1554 Score = 40.7 bits (91), Expect = 8e-04 Identities = 32/106 (30%), Positives = 50/106 (47%), Gaps = 19/106 (17%) Frame = -2 Query: 539 PVCGSNGKTYANKCSL---ECTQ-KIIPSLKMEHDGECQ----GAKLASLH--------- 411 PVCGS+ ++Y N C L C Q +I L+ + CQ A +S Sbjct: 1730 PVCGSDLQSYDNVCFLRMQSCQQISLITVLRPNYCDPCQNFICSAPYSSCEVKDNEAVCE 1789 Query: 410 -PCICTREKGPVCGSDGVTYSNLCLL-KCASLSKPSLSIEHTGPCD 279 P C +E VCG++ TY+N C++ K A ++ +++ G CD Sbjct: 1790 CPKDCPKEDAEVCGTNWKTYTNECMMRKQACMNNSMVTVRSIGRCD 1835 Score = 40.3 bits (90), Expect = 0.001 Identities = 21/59 (35%), Positives = 34/59 (57%), Gaps = 4/59 (6%) Frame = -2 Query: 443 ECQGAKLASLHPCICT--REKG-PVCGSDGVTYSNLC-LLKCASLSKPSLSIEHTGPCD 279 +C+ K + + C C ++K PVCGSD VTY++ C L + A L+ ++ + G CD Sbjct: 205 DCEADKSSGVITCKCPDCKDKSDPVCGSDNVTYASECQLRRAACLNDTWITTQRKGDCD 263 Score = 39.5 bits (88), Expect = 0.002 Identities = 32/106 (30%), Positives = 46/106 (43%), Gaps = 20/106 (18%) Frame = -2 Query: 536 VCGSNGKTYANKCSLECTQ-KIIPSLKMEHDGECQ--------GAKLASLH--------- 411 VCG++ TY+N+C ++ + +LK++ G+C A +S Sbjct: 1520 VCGTDNITYSNECLMKYQACRTNSALKVKRKGDCDVCKDFDCSSAPYSSCEAVNDKPICV 1579 Query: 410 -PCICTREKGPVCGSDGVTYSNLCLLK-CASLSKPSLSIEHTGPCD 279 P IC PVC SD TY N C +K A S L+ G CD Sbjct: 1580 CPKICPITLDPVCASDNNTYPNECAMKQLACQSAKVLTFRRKGDCD 1625 Score = 38.3 bits (85), Expect = 0.004 Identities = 17/46 (36%), Positives = 25/46 (54%), Gaps = 3/46 (6%) Frame = -2 Query: 410 PCICTREKGPVCGSDGVTYSNLCLLK---CASLSKPSLSIEHTGPC 282 P CT E P+C SDG TY N CL++ C + +++ + PC Sbjct: 2155 PDDCTNETKPICASDGQTYDNECLMQKRACENNQNLNVTSDRACPC 2200 Score = 37.9 bits (84), Expect = 0.005 Identities = 31/107 (28%), Positives = 48/107 (44%), Gaps = 20/107 (18%) Frame = -2 Query: 539 PVCGSNGKTYANKCSLE---C---TQKIIPSLKMEH---DGECQGAKLASLHP------C 405 PV G++ K Y N+C L+ C T+ +I + D C +S P C Sbjct: 1074 PVYGTDNKNYDNECLLKLAACKSNTRILIAGFGRYNPCKDVNCTSPPYSSCRPLDNKPVC 1133 Query: 404 ICTREKG----PVCGSDGVTYSNLCLLK-CASLSKPSLSIEHTGPCD 279 C PVCG+D TY N CL++ A ++ ++++ G CD Sbjct: 1134 ACPENCSSTVDPVCGTDNNTYDNECLMRQQACVANATVAVRRKGHCD 1180 Score = 36.7 bits (81), Expect = 0.012 Identities = 25/88 (28%), Positives = 40/88 (45%), Gaps = 19/88 (21%) Frame = -2 Query: 539 PVCGSNGKTYANKCSLEC----TQKIIPSLKMEHDGECQGAKLAS-----------LHPC 405 PVCGS+ Y N+C ++ T K I + + + C+ ++ C Sbjct: 1383 PVCGSDNNDYDNECLMQARACATNKTITAHRNGYCDPCKNHSCSTPPYSTCKAVDDKAEC 1442 Query: 404 ICT----REKGPVCGSDGVTYSNLCLLK 333 +C+ R VCG+D +TY+N C LK Sbjct: 1443 VCSKVCPRSLDLVCGTDNITYNNECFLK 1470 Score = 35.9 bits (79), Expect = 0.022 Identities = 31/108 (28%), Positives = 47/108 (43%), Gaps = 22/108 (20%) Frame = -2 Query: 539 PVCGSNGKTYANKCSLECTQKIIPS-LKMEHDGECQGAKLASL-------------HP-C 405 PVCGS+ TYA++C L + + + + G+C K S P C Sbjct: 228 PVCGSDNVTYASECQLRRAACLNDTWITTQRKGDCDVCKDVSCTSPPFSTCVALNGRPAC 287 Query: 404 ICTREKG------PVCGSDGVTYSNLCLLKCASL-SKPSLSIEHTGPC 282 C G P+CGS+ TY+N C L+ S + S++I+ C Sbjct: 288 SCPSSCGDESLPQPICGSNNKTYANECELRMDSCKNNKSIAIQFRKEC 335 Score = 35.9 bits (79), Expect = 0.022 Identities = 18/41 (43%), Positives = 22/41 (53%), Gaps = 5/41 (12%) Frame = -2 Query: 539 PVCGSNGKTYANKCSL---EC--TQKIIPSLKMEHDGECQG 432 P+CGSN KTYAN+C L C + I + E CQG Sbjct: 301 PICGSNNKTYANECELRMDSCKNNKSIAIQFRKECPAPCQG 341 Score = 35.9 bits (79), Expect = 0.022 Identities = 32/105 (30%), Positives = 49/105 (46%), Gaps = 19/105 (18%) Frame = -2 Query: 539 PVCGSNGKTYANKCSLE---C--TQKIIPSLKMEHDG----ECQGAKLASL------HPC 405 PVCGS+ KTY N+C + C + II + + E D C +S C Sbjct: 618 PVCGSDSKTYPNECRMRQEACWNNKWIIVAQQEECDPCNKYNCITPPYSSCTTKDNKPTC 677 Query: 404 I---CTREKGPVCGSDGVTYSNLCLLKC-ASLSKPSLSIEHTGPC 282 I C + PVCG++ TY++ C L+ A + S+ ++ PC Sbjct: 678 ICPECPQVDKPVCGTNNKTYTSECALQVDACKTNTSIDVQLDKPC 722 Score = 34.7 bits (76), Expect = 0.050 Identities = 20/58 (34%), Positives = 30/58 (51%), Gaps = 3/58 (5%) Frame = -2 Query: 446 GECQ--GAKLASLHPCICTREKGPVCGSDGVTYSNLC-LLKCASLSKPSLSIEHTGPC 282 GEC+ G + P C PVCGSDGVTY + C +++ A + S+++ C Sbjct: 2612 GECKVVGDMPQCVCPPACKPTLTPVCGSDGVTYESECGMIQKACQTNTSITLVANEAC 2669 Score = 34.3 bits (75), Expect = 0.067 Identities = 15/42 (35%), Positives = 22/42 (52%), Gaps = 1/42 (2%) Frame = -2 Query: 401 CTREKGPVCGSDGVTYSNLCLLKC-ASLSKPSLSIEHTGPCD 279 C + PVCGSD Y N CL++ A + +++ G CD Sbjct: 1377 CPKTLKPVCGSDNNDYDNECLMQARACATNKTITAHRNGYCD 1418 Score = 33.9 bits (74), Expect = 0.088 Identities = 27/91 (29%), Positives = 39/91 (42%), Gaps = 19/91 (20%) Frame = -2 Query: 539 PVCGSNGKTYANKCSLE---CTQKIIPSLKMEHDGE------CQG-----AKLASLHP-C 405 PVCGS+ TY N+C + C +++ + D + C K P C Sbjct: 1216 PVCGSDNNTYDNECLMRQQACVANTTVAVRRKGDCDPCSNVTCDSPPYSTCKAQDDQPTC 1275 Query: 404 ICT----REKGPVCGSDGVTYSNLCLLKCAS 324 +C + PV G+D Y N CLLK A+ Sbjct: 1276 VCVEPCPKTLKPVYGTDNKNYDNECLLKLAA 1306 Score = 33.5 bits (73), Expect = 0.12 Identities = 31/110 (28%), Positives = 48/110 (43%), Gaps = 21/110 (19%) Frame = -2 Query: 548 EYAPVCGSNGKTYANKCSLE---CTQKIIPSLK-MEHDGECQGAKLASLHP--------- 408 E A VCG+N KTY N+C + C + +++ + C S +P Sbjct: 1797 EDAEVCGTNWKTYTNECMMRKQACMNNSMVTVRSIGRCDPCVRYDCGSTNPYSTCKPKGD 1856 Query: 407 ----CI---CTREKGPVCGSDGVTYSNLCLLKCASLSKPS-LSIEHTGPC 282 CI C + K +C S+ +TY + C L+ AS L+I+ G C Sbjct: 1857 SGFECICPTCPKAKDYLCASNNLTYMSKCHLERASCQLGRYLTIKQKGKC 1906 Score = 32.7 bits (71), Expect = 0.20 Identities = 11/23 (47%), Positives = 16/23 (69%) Frame = -2 Query: 401 CTREKGPVCGSDGVTYSNLCLLK 333 C++ + PVCGSD TY N C ++ Sbjct: 612 CSKREDPVCGSDSKTYPNECRMR 634 Score = 30.3 bits (65), Expect = 1.1 Identities = 25/89 (28%), Positives = 36/89 (40%), Gaps = 16/89 (17%) Frame = -2 Query: 542 APVCGSNGKTYANKCSLE---CTQK-------IIPSLKMEHDGE----CQGAKLASLHPC 405 +PVC ++GK + N+C + C K P D C+ C Sbjct: 1005 SPVCTNDGKKFPNECQMRQDACFNKQWTTPISCDPCSNFTCDSPPYSTCKAQDDQPTCVC 1064 Query: 404 I--CTREKGPVCGSDGVTYSNLCLLKCAS 324 + C + PV G+D Y N CLLK A+ Sbjct: 1065 VEPCPKTLKPVYGTDNKNYDNECLLKLAA 1093 Score = 28.7 bits (61), Expect = 3.3 Identities = 9/20 (45%), Positives = 15/20 (75%) Frame = -2 Query: 548 EYAPVCGSNGKTYANKCSLE 489 E P+C S+G+TY N+C ++ Sbjct: 2161 ETKPICASDGQTYDNECLMQ 2180 Score = 27.5 bits (58), Expect = 7.6 Identities = 18/67 (26%), Positives = 30/67 (44%), Gaps = 7/67 (10%) Frame = -2 Query: 461 KMEHDGECQGAKLASLHPCICTREKGP------VCGSDGVTYSNLCLLKCASLSKP-SLS 303 K + GE ++ C+C P VC SDG+TY ++C + + S S+ Sbjct: 2982 KCRYQGEVCVTDSRNVPRCVCPPGCPPAEVSQRVCASDGLTYPSVCEMHRTACSLGISIQ 3041 Query: 302 IEHTGPC 282 ++ G C Sbjct: 3042 AKYRGSC 3048 >SB_50468| Best HMM Match : Kazal_1 (HMM E-Value=1.3e-15) Length = 1724 Score = 43.6 bits (98), Expect = 1e-04 Identities = 19/44 (43%), Positives = 25/44 (56%), Gaps = 1/44 (2%) Frame = -2 Query: 410 PCICTREKGPVCGSDGVTYSNLCLLKCASLSK-PSLSIEHTGPC 282 P CTRE PVCGSDG TY C+++ + SK + + G C Sbjct: 48 PMACTREYAPVCGSDGKTYPTECVMQVDACSKNKDIKVAFKGTC 91 Score = 37.1 bits (82), Expect = 0.009 Identities = 17/40 (42%), Positives = 25/40 (62%), Gaps = 3/40 (7%) Frame = -2 Query: 548 EYAPVCGSNGKTYANKCSLE---CTQKIIPSLKMEHDGEC 438 EYAPVCGS+GKTY +C ++ C++ +K+ G C Sbjct: 54 EYAPVCGSDGKTYPTECVMQVDACSKN--KDIKVAFKGTC 91 >SB_33512| Best HMM Match : Kazal_1 (HMM E-Value=2.6e-20) Length = 87 Score = 40.7 bits (91), Expect = 8e-04 Identities = 25/73 (34%), Positives = 37/73 (50%), Gaps = 1/73 (1%) Frame = -2 Query: 539 PVCGSNGKTYANKCSLECTQKII-PSLKMEHDGECQGAKLASLHPCICTREKGPVCGSDG 363 PVCGS+ TY N+C + + ++ + G+C+ PC T + PV G+D Sbjct: 9 PVCGSDNNTYDNECLMRQQACVANTTVAVRRKGDCE--------PCPKTLK--PVYGTDN 58 Query: 362 VTYSNLCLLKCAS 324 Y N CLLK A+ Sbjct: 59 KNYDNECLLKLAA 71 Score = 36.7 bits (81), Expect = 0.012 Identities = 15/42 (35%), Positives = 25/42 (59%), Gaps = 1/42 (2%) Frame = -2 Query: 401 CTREKGPVCGSDGVTYSNLCLLK-CASLSKPSLSIEHTGPCD 279 C+ PVCGSD TY N CL++ A ++ ++++ G C+ Sbjct: 3 CSSTVDPVCGSDNNTYDNECLMRQQACVANTTVAVRRKGDCE 44 >SB_44627| Best HMM Match : Kazal_1 (HMM E-Value=3.19496e-43) Length = 260 Score = 39.9 bits (89), Expect = 0.001 Identities = 39/111 (35%), Positives = 50/111 (45%), Gaps = 25/111 (22%) Frame = -2 Query: 539 PVCGSNGKTYANKCSLE---CTQK--IIPSLKMEHDGECQGA----------KLASLHP- 408 PV GS+GK Y N+C L+ C K I+ + + G C G K+ P Sbjct: 9 PVYGSDGKDYDNECLLKLAACKSKSRILIAGFGRYPGPCSGVTCDSPPYSTCKVQDDKPT 68 Query: 407 CICTRE----KGPVCGSDGVTYSNLCLLKCASL-SKPSLSI----EHTGPC 282 C+C PV GSDG Y N CLLK A+ SK + I + GPC Sbjct: 69 CVCVEPCPEILKPVYGSDGKDYDNECLLKLAACKSKSRILIAGFGRYPGPC 119 Score = 38.7 bits (86), Expect = 0.003 Identities = 39/111 (35%), Positives = 49/111 (44%), Gaps = 25/111 (22%) Frame = -2 Query: 539 PVCGSNGKTYANKCSLE---CTQK--IIPSLKMEHDGECQGA----------KLASLHP- 408 PV GS+GK Y N+C L+ C K I+ + + G C G K+ P Sbjct: 81 PVYGSDGKDYDNECLLKLAACKSKSRILIAGFGRYPGPCSGVTCDSPPYSTCKVQDDKPT 140 Query: 407 CICTRE----KGPVCGSDGVTYSNLCLLK-CASLSKPSLSI----EHTGPC 282 C+C PV GSDG Y N CLLK A SK + I + GPC Sbjct: 141 CVCVEPCPEILKPVYGSDGKDYDNECLLKLSACKSKSRILIAGFGRYPGPC 191 Score = 38.7 bits (86), Expect = 0.003 Identities = 34/97 (35%), Positives = 43/97 (44%), Gaps = 20/97 (20%) Frame = -2 Query: 539 PVCGSNGKTYANKCSLE---CTQK--IIPSLKMEHDGECQGA----------KLASLHP- 408 PV GS+GK Y N+C L+ C K I+ + + G C G K+ P Sbjct: 153 PVYGSDGKDYDNECLLKLSACKSKSRILIAGFGRYPGPCSGVTCDSPPYSTCKVQDDKPT 212 Query: 407 CICTRE----KGPVCGSDGVTYSNLCLLKCASLSKPS 309 C+C PV GSDG Y N CLLK A+ S Sbjct: 213 CVCVEPCPEILKPVYGSDGKDYDNECLLKLAACKSKS 249 Score = 32.3 bits (70), Expect = 0.27 Identities = 20/45 (44%), Positives = 23/45 (51%), Gaps = 5/45 (11%) Frame = -2 Query: 401 CTREKGPVCGSDGVTYSNLCLLKCASL-SKPSLSI----EHTGPC 282 C PV GSDG Y N CLLK A+ SK + I + GPC Sbjct: 3 CPEILKPVYGSDGKDYDNECLLKLAACKSKSRILIAGFGRYPGPC 47 >SB_33374| Best HMM Match : No HMM Matches (HMM E-Value=.) Length = 4475 Score = 39.9 bits (89), Expect = 0.001 Identities = 19/41 (46%), Positives = 24/41 (58%), Gaps = 1/41 (2%) Frame = -2 Query: 401 CTREKGPVCGSDGVTYSNLCLLKCASL-SKPSLSIEHTGPC 282 C PVCGSDG TY N C LK A+ SK ++++ G C Sbjct: 3974 CPSTSKPVCGSDGKTYKNECELKRAACESKKNVTVASQGEC 4014 Score = 39.1 bits (87), Expect = 0.002 Identities = 16/29 (55%), Positives = 20/29 (68%) Frame = -2 Query: 410 PCICTREKGPVCGSDGVTYSNLCLLKCAS 324 P C +K PVCG+DG TY NLC ++ AS Sbjct: 4238 PSRCLPDKEPVCGADGKTYRNLCEIRKAS 4266 Score = 36.7 bits (81), Expect = 0.012 Identities = 34/94 (36%), Positives = 43/94 (45%), Gaps = 20/94 (21%) Frame = -2 Query: 545 YAPVCGSNGKTYANKCSLE---CT--QKII--------PSLKMEHDGE----CQ---GAK 426 Y PV GS+GK Y N+C L+ CT ++II P D C+ K Sbjct: 229 YDPVYGSDGKNYDNECELKRAACTTNKRIILAGRGRVHPCAGFSCDSPPYSTCKVQDDGK 288 Query: 425 LASLHPCICTREKGPVCGSDGVTYSNLCLLKCAS 324 A + P C + PV GSDG Y N C LK A+ Sbjct: 289 PACVCPPKCEKVYDPVYGSDGKNYDNECELKRAA 322 Score = 35.5 bits (78), Expect = 0.029 Identities = 17/37 (45%), Positives = 23/37 (62%), Gaps = 3/37 (8%) Frame = -2 Query: 539 PVCGSNGKTYANKCSLE---CTQKIIPSLKMEHDGEC 438 PVCGS+GKTY N+C L+ C K ++ + GEC Sbjct: 3980 PVCGSDGKTYKNECELKRAACESK--KNVTVASQGEC 4014 Score = 33.5 bits (73), Expect = 0.12 Identities = 23/65 (35%), Positives = 31/65 (47%), Gaps = 1/65 (1%) Frame = -2 Query: 515 TYANKCS-LECTQKIIPSLKMEHDGECQGAKLASLHPCICTREKGPVCGSDGVTYSNLCL 339 T A+ C+ C + K++ DG K A + P C + PV GSDG Y N C Sbjct: 191 TTADPCAGFNCDSPPYSTCKVQDDG-----KPACVCPPKCEKVYDPVYGSDGKNYDNECE 245 Query: 338 LKCAS 324 LK A+ Sbjct: 246 LKRAA 250 Score = 30.3 bits (65), Expect = 1.1 Identities = 10/16 (62%), Positives = 13/16 (81%) Frame = -2 Query: 539 PVCGSNGKTYANKCSL 492 PVCG++GKTY N C + Sbjct: 4247 PVCGADGKTYRNLCEI 4262 >SB_6081| Best HMM Match : No HMM Matches (HMM E-Value=.) Length = 56 Score = 39.1 bits (87), Expect = 0.002 Identities = 18/41 (43%), Positives = 27/41 (65%), Gaps = 3/41 (7%) Frame = -2 Query: 548 EYAPVCGSNGKTYANKCSLE---CTQKIIPSLKMEHDGECQ 435 +Y PVCGS+G+TY N+ S+E C + + LK+ GEC+ Sbjct: 17 DYNPVCGSDGRTYPNRASMEVQGCLKNTV--LKIVSQGECR 55 Score = 31.9 bits (69), Expect = 0.36 Identities = 17/44 (38%), Positives = 20/44 (45%), Gaps = 1/44 (2%) Frame = -2 Query: 410 PCICTREKGPVCGSDGVTYSNLCLLKC-ASLSKPSLSIEHTGPC 282 P T + PVCGSDG TY N ++ L L I G C Sbjct: 11 PMAVTADYNPVCGSDGRTYPNRASMEVQGCLKNTVLKIVSQGEC 54 >SB_23052| Best HMM Match : No HMM Matches (HMM E-Value=.) Length = 479 Score = 38.7 bits (86), Expect = 0.003 Identities = 25/86 (29%), Positives = 39/86 (45%) Frame = -2 Query: 539 PVCGSNGKTYANKCSLECTQKIIPSLKMEHDGECQGAKLASLHPCICTREKGPVCGSDGV 360 PVC ++G+ + N CSL K K+ + G C+ C PVCG +G Sbjct: 191 PVCDTDGQQHPNLCSLHFQGK-----KLAYKGFCKS---------YCKSPTKPVCGVNGE 236 Query: 359 TYSNLCLLKCASLSKPSLSIEHTGPC 282 TYS++C + +++ GPC Sbjct: 237 TYSSIC-----GAHSARVVVDYEGPC 257 >SB_35516| Best HMM Match : Kazal_1 (HMM E-Value=0) Length = 320 Score = 38.7 bits (86), Expect = 0.003 Identities = 24/73 (32%), Positives = 36/73 (49%), Gaps = 1/73 (1%) Frame = -2 Query: 539 PVCGSNGKTYANKCSLECTQKII-PSLKMEHDGECQGAKLASLHPCICTREKGPVCGSDG 363 PVCG++ TY N+C + + ++ + G C+ PC T + PV G+D Sbjct: 171 PVCGTDNNTYDNECLMRQQACVANATVAVRRKGHCE--------PCPKTLK--PVYGTDN 220 Query: 362 VTYSNLCLLKCAS 324 Y N CLLK A+ Sbjct: 221 KNYDNECLLKLAA 233 Score = 37.1 bits (82), Expect = 0.009 Identities = 31/106 (29%), Positives = 47/106 (44%), Gaps = 20/106 (18%) Frame = -2 Query: 539 PVCGSNGKTYANKCSLE---C---TQKIIPSLKMEH---DGECQGAKLASLHP------C 405 PV G++ K Y N+C L+ C T+ +I + D C +S P C Sbjct: 214 PVYGTDNKNYDNECLLKLAACKSNTRILIAGFGRYNPCKDVNCTSPPYSSCRPLDNKPVC 273 Query: 404 ICTREKG----PVCGSDGVTYSNLCLLK-CASLSKPSLSIEHTGPC 282 C PVCGSD TY N CL++ A ++ ++++ G C Sbjct: 274 ACPENCSSTVDPVCGSDNNTYDNECLMRQQACVANTTVAVRRKGDC 319 Score = 36.3 bits (80), Expect = 0.017 Identities = 30/107 (28%), Positives = 48/107 (44%), Gaps = 20/107 (18%) Frame = -2 Query: 539 PVCGSNGKTYANKCSLE---C---TQKIIPSLKMEH---DGECQGAKLASLHP------C 405 PV G++ K Y N+C L+ C T+ +I + D C +S P C Sbjct: 100 PVYGTDNKNYDNECLLKLAACKSNTRILIAGFGRYNPCKDVNCTSPPYSSCRPLDNKPVC 159 Query: 404 ICTREKG----PVCGSDGVTYSNLCLLK-CASLSKPSLSIEHTGPCD 279 C PVCG+D TY N CL++ A ++ ++++ G C+ Sbjct: 160 ACPENCSSTVDPVCGTDNNTYDNECLMRQQACVANATVAVRRKGHCE 206 Score = 30.3 bits (65), Expect = 1.1 Identities = 25/89 (28%), Positives = 36/89 (40%), Gaps = 16/89 (17%) Frame = -2 Query: 542 APVCGSNGKTYANKCSLE---CTQK-------IIPSLKMEHDGE----CQGAKLASLHPC 405 +PVC ++GK + N+C + C K P D C+ C Sbjct: 31 SPVCTNDGKKFPNECQMRQDACFNKQWTTPISCDPCSNFTCDSPPYSTCKAQDDQPTCVC 90 Query: 404 I--CTREKGPVCGSDGVTYSNLCLLKCAS 324 + C + PV G+D Y N CLLK A+ Sbjct: 91 VEPCPKTLKPVYGTDNKNYDNECLLKLAA 119 >SB_37368| Best HMM Match : Kazal_1 (HMM E-Value=9.2e-09) Length = 68 Score = 38.3 bits (85), Expect = 0.004 Identities = 17/39 (43%), Positives = 22/39 (56%), Gaps = 3/39 (7%) Frame = -2 Query: 383 PVCGSDGVTYSNLCLL---KCASLSKPSLSIEHTGPCDN 276 PVCGSD VTY+N C L C + ++I H G C + Sbjct: 20 PVCGSDDVTYANACTLDERNCRATDMGYVTIRHLGECSS 58 Score = 34.3 bits (75), Expect = 0.067 Identities = 16/37 (43%), Positives = 22/37 (59%), Gaps = 3/37 (8%) Frame = -2 Query: 539 PVCGSNGKTYANKCSLE---CTQKIIPSLKMEHDGEC 438 PVCGS+ TYAN C+L+ C + + + H GEC Sbjct: 20 PVCGSDDVTYANACTLDERNCRATDMGYVTIRHLGEC 56 >SB_32965| Best HMM Match : Kazal_1 (HMM E-Value=3.4e-19) Length = 69 Score = 38.3 bits (85), Expect = 0.004 Identities = 20/65 (30%), Positives = 33/65 (50%), Gaps = 3/65 (4%) Frame = -2 Query: 467 SLKMEHDGECQGAKLASLHPCI--CTREKGPVCGSDGVTYSNLCLLKCASL-SKPSLSIE 297 ++ +E D L + C+ C PVCG+DG TY N C+L A+ S ++++ Sbjct: 4 TINIEKDFLFDFKALPQVDKCVRPCPAINDPVCGTDGKTYGNECMLGAATCHSNGTITLA 63 Query: 296 HTGPC 282 + G C Sbjct: 64 YPGEC 68 Score = 34.7 bits (76), Expect = 0.050 Identities = 15/35 (42%), Positives = 22/35 (62%), Gaps = 1/35 (2%) Frame = -2 Query: 539 PVCGSNGKTYANKCSL-ECTQKIIPSLKMEHDGEC 438 PVCG++GKTY N+C L T ++ + + GEC Sbjct: 34 PVCGTDGKTYGNECMLGAATCHSNGTITLAYPGEC 68 >SB_33509| Best HMM Match : Kazal_1 (HMM E-Value=2.3e-26) Length = 143 Score = 36.7 bits (81), Expect = 0.012 Identities = 15/42 (35%), Positives = 25/42 (59%), Gaps = 1/42 (2%) Frame = -2 Query: 401 CTREKGPVCGSDGVTYSNLCLLK-CASLSKPSLSIEHTGPCD 279 C+ PVCG+D TY N CL++ A ++ ++++ G CD Sbjct: 31 CSSTVDPVCGTDNNTYDNECLMRQQACVANATVAVRRKGHCD 72 Score = 31.9 bits (69), Expect = 0.36 Identities = 25/91 (27%), Positives = 39/91 (42%), Gaps = 19/91 (20%) Frame = -2 Query: 539 PVCGSNGKTYANKCSLECTQKII-PSLKMEHDGECQG-AKLASLHP-------------C 405 PVCG++ TY N+C + + ++ + G C +K+ P C Sbjct: 37 PVCGTDNNTYDNECLMRQQACVANATVAVRRKGHCDPCSKVTCDSPPYSTCKAQDDKPTC 96 Query: 404 ICT----REKGPVCGSDGVTYSNLCLLKCAS 324 +C + PV G+D Y N CLLK A+ Sbjct: 97 VCVEPCPKTLKPVYGTDNKNYDNECLLKLAA 127 >SB_33373| Best HMM Match : No HMM Matches (HMM E-Value=.) Length = 720 Score = 36.7 bits (81), Expect = 0.012 Identities = 32/94 (34%), Positives = 41/94 (43%), Gaps = 20/94 (21%) Frame = -2 Query: 545 YAPVCGSNGKTYANKCSLE---CTQ----------KIIPSLKMEHDGE----CQ---GAK 426 Y PV GS+GK Y N+C L+ CT ++ P D C+ K Sbjct: 155 YDPVYGSDGKNYDNECELKRAACTSNRRIILAGRGRVHPCAGFSCDSPPYSTCKVQDDGK 214 Query: 425 LASLHPCICTREKGPVCGSDGVTYSNLCLLKCAS 324 A + P C + PV GSDG Y N C LK A+ Sbjct: 215 PACVCPPKCEKVYDPVYGSDGKNYDNECELKRAA 248 Score = 35.5 bits (78), Expect = 0.029 Identities = 33/94 (35%), Positives = 43/94 (45%), Gaps = 20/94 (21%) Frame = -2 Query: 545 YAPVCGSNGKTYANKCSLE---CT--QKII--------PSLKMEHDGE----CQ---GAK 426 Y PV GS+GK Y N+C L+ CT ++II P D C+ K Sbjct: 528 YDPVYGSDGKNYDNECELKRAACTTNKRIILAGRGRVHPCAGFSCDSPPYSTCKVQDDGK 587 Query: 425 LASLHPCICTREKGPVCGSDGVTYSNLCLLKCAS 324 + + P C + PV GSDG Y N C LK A+ Sbjct: 588 PSCVCPPKCEKVYDPVYGSDGKNYDNECELKRAA 621 Score = 31.9 bits (69), Expect = 0.36 Identities = 22/65 (33%), Positives = 31/65 (47%), Gaps = 1/65 (1%) Frame = -2 Query: 515 TYANKCS-LECTQKIIPSLKMEHDGECQGAKLASLHPCICTREKGPVCGSDGVTYSNLCL 339 T A+ C+ C + +++ DG K A + P C + PV GSDG Y N C Sbjct: 490 TTADPCAGFNCDSPPYSTCEVQDDG-----KPACVCPPKCEKVYDPVYGSDGKNYDNECE 544 Query: 338 LKCAS 324 LK A+ Sbjct: 545 LKRAA 549 Score = 30.3 bits (65), Expect = 1.1 Identities = 16/35 (45%), Positives = 19/35 (54%) Frame = -2 Query: 428 KLASLHPCICTREKGPVCGSDGVTYSNLCLLKCAS 324 K A + P C + PV GSDG Y N C LK A+ Sbjct: 23 KPACVCPPKCEKVYDPVYGSDGKNYDNECELKRAA 57 Score = 30.3 bits (65), Expect = 1.1 Identities = 16/35 (45%), Positives = 19/35 (54%) Frame = -2 Query: 428 KLASLHPCICTREKGPVCGSDGVTYSNLCLLKCAS 324 K A + P C + PV GSDG Y N C LK A+ Sbjct: 142 KPACVCPPKCEKVYDPVYGSDGKNYDNECELKRAA 176 Score = 30.3 bits (65), Expect = 1.1 Identities = 21/65 (32%), Positives = 30/65 (46%), Gaps = 1/65 (1%) Frame = -2 Query: 515 TYANKCS-LECTQKIIPSLKMEHDGECQGAKLASLHPCICTREKGPVCGSDGVTYSNLCL 339 T + C+ C + K++ DG K + + P C + PV GSDG Y N C Sbjct: 644 TTPDPCAGFSCDSPPYSTCKVQDDG-----KPSCVCPPKCEKVYDPVYGSDGKNYDNECE 698 Query: 338 LKCAS 324 LK A+ Sbjct: 699 LKRAA 703 Score = 29.1 bits (62), Expect = 2.5 Identities = 11/19 (57%), Positives = 14/19 (73%) Frame = -2 Query: 545 YAPVCGSNGKTYANKCSLE 489 Y PV GS+GK Y N+C L+ Sbjct: 36 YDPVYGSDGKNYDNECELK 54 Score = 29.1 bits (62), Expect = 2.5 Identities = 11/19 (57%), Positives = 14/19 (73%) Frame = -2 Query: 545 YAPVCGSNGKTYANKCSLE 489 Y PV GS+GK Y N+C L+ Sbjct: 682 YDPVYGSDGKNYDNECELK 700 >SB_58159| Best HMM Match : No HMM Matches (HMM E-Value=.) Length = 443 Score = 35.9 bits (79), Expect = 0.022 Identities = 15/41 (36%), Positives = 26/41 (63%) Frame = -2 Query: 548 EYAPVCGSNGKTYANKCSLECTQKIIPSLKMEHDGECQGAK 426 E +PVCG++ +TYA++C L+ + +KM + G C+ K Sbjct: 213 EASPVCGTDMRTYASRCHLQLAKCKGHKVKMIYKGRCKEIK 253 Score = 33.1 bits (72), Expect = 0.15 Identities = 14/40 (35%), Positives = 21/40 (52%) Frame = -2 Query: 401 CTREKGPVCGSDGVTYSNLCLLKCASLSKPSLSIEHTGPC 282 C E PVCG+D TY++ C L+ A + + + G C Sbjct: 210 CPSEASPVCGTDMRTYASRCHLQLAKCKGHKVKMIYKGRC 249 >SB_30470| Best HMM Match : No HMM Matches (HMM E-Value=.) Length = 912 Score = 34.3 bits (75), Expect = 0.067 Identities = 16/44 (36%), Positives = 22/44 (50%), Gaps = 1/44 (2%) Frame = -2 Query: 410 PCICTREKGPVCGSDGVTYSNLCLLKCASLSK-PSLSIEHTGPC 282 P C + CG D VTY+N C + A + ++ I H GPC Sbjct: 301 PHNCATYENQRCGEDNVTYTNECTHQKAMCDQTQTIGIRHMGPC 344 >SB_17430| Best HMM Match : Kazal_1 (HMM E-Value=1e-07) Length = 396 Score = 34.3 bits (75), Expect = 0.067 Identities = 16/35 (45%), Positives = 22/35 (62%), Gaps = 1/35 (2%) Frame = -2 Query: 377 CGSDGVTYSNLCLL-KCASLSKPSLSIEHTGPCDN 276 CGSDGVTY N CL K ++ +++I H G C + Sbjct: 33 CGSDGVTYKNDCLYKKYICETRLNVTIVHLGACQH 67 >SB_3798| Best HMM Match : No HMM Matches (HMM E-Value=.) Length = 351 Score = 34.3 bits (75), Expect = 0.067 Identities = 14/34 (41%), Positives = 22/34 (64%), Gaps = 1/34 (2%) Frame = -2 Query: 380 VCGSDGVTYSNLCLLKCASLS-KPSLSIEHTGPC 282 VCG+DGVTY +LC L+ A+ ++ + + G C Sbjct: 143 VCGADGVTYGSLCRLRVATCKLGKTIGVAYLGSC 176 Score = 33.9 bits (74), Expect = 0.088 Identities = 16/34 (47%), Positives = 22/34 (64%), Gaps = 1/34 (2%) Frame = -2 Query: 380 VCGSDGVTYSNLCLLKCASLSKPSL-SIEHTGPC 282 +CG+DG TYS+ C L+ S + L SI+H G C Sbjct: 232 ICGTDGRTYSSFCALREHSCNVGRLYSIKHIGRC 265 Score = 30.3 bits (65), Expect = 1.1 Identities = 22/88 (25%), Positives = 39/88 (44%), Gaps = 4/88 (4%) Frame = -2 Query: 536 VCGSNGKTYANKCSLE-CTQKIIPSLKMEHDGEC-QGAKLASLHPCICTREKGPVCGSDG 363 VCG++G TY + C L T K+ ++ + + G C +G+ +++ C+R K + G Sbjct: 143 VCGADGVTYGSLCRLRVATCKLGKTIGVAYLGSCKEGSDCSTVK---CSRHKRCLTDETG 199 Query: 362 VTYSNLC--LLKCASLSKPSLSIEHTGP 285 C C +S+P P Sbjct: 200 QPRCTSCHTHFNCRRMSRPQSQDNEDSP 227 Score = 27.5 bits (58), Expect = 7.6 Identities = 11/34 (32%), Positives = 22/34 (64%), Gaps = 1/34 (2%) Frame = -2 Query: 536 VCGSNGKTYANKCSL-ECTQKIIPSLKMEHDGEC 438 +CG++G+TY++ C+L E + + ++H G C Sbjct: 232 ICGTDGRTYSSFCALREHSCNVGRLYSIKHIGRC 265 >SB_59417| Best HMM Match : No HMM Matches (HMM E-Value=.) Length = 1822 Score = 34.3 bits (75), Expect = 0.067 Identities = 16/44 (36%), Positives = 25/44 (56%), Gaps = 1/44 (2%) Frame = -2 Query: 407 CICTREKGPVCGSDGVTYSNLC-LLKCASLSKPSLSIEHTGPCD 279 C + +C SDG+TY++ C L K A L S+++ + G CD Sbjct: 53 CSPAQPSDRLCASDGITYNSKCELNKTACLLGSSITVLYRGACD 96 >SB_57668| Best HMM Match : No HMM Matches (HMM E-Value=.) Length = 1107 Score = 33.9 bits (74), Expect = 0.088 Identities = 17/44 (38%), Positives = 24/44 (54%), Gaps = 4/44 (9%) Frame = -2 Query: 407 CICTRE----KGPVCGSDGVTYSNLCLLKCASLSKPSLSIEHTG 288 C CT + PV GSD V Y N CL++ ++ + PS + TG Sbjct: 873 CACTMQCPSLLDPVVGSDNVMYMNECLMRMSAYNFPSTTYPPTG 916 >SB_13131| Best HMM Match : No HMM Matches (HMM E-Value=.) Length = 645 Score = 33.9 bits (74), Expect = 0.088 Identities = 16/35 (45%), Positives = 22/35 (62%), Gaps = 1/35 (2%) Frame = -2 Query: 377 CGSDGVTYSNLCLL-KCASLSKPSLSIEHTGPCDN 276 CGSDGVTY N CL K ++ +++I H G C + Sbjct: 187 CGSDGVTYKNDCLYKKYICETRLNVTIVHLGGCQH 221 >SB_28600| Best HMM Match : EGF_CA (HMM E-Value=4.2e-40) Length = 1042 Score = 32.7 bits (71), Expect = 0.20 Identities = 24/64 (37%), Positives = 31/64 (48%), Gaps = 6/64 (9%) Frame = -2 Query: 455 EHDGECQGAKLASLHPCICTREKGP-----VCGSDGVTYSNLCLL-KCASLSKPSLSIEH 294 E+ EC+ A A C+C K P VCG++G T+ NLCL K K + S H Sbjct: 198 EYFAECE-AFAADDAQCVCP-SKCPAYIDQVCGTNGQTFDNLCLFKKHVCRIKGNFSYLH 255 Query: 293 TGPC 282 G C Sbjct: 256 HGSC 259 Score = 29.5 bits (63), Expect = 1.9 Identities = 14/40 (35%), Positives = 21/40 (52%), Gaps = 1/40 (2%) Frame = -2 Query: 536 VCGSNGKTYANKCSL-ECTQKIIPSLKMEHDGECQGAKLA 420 VCG+NG+T+ N C + +I + H G C+G A Sbjct: 226 VCGTNGQTFDNLCLFKKHVCRIKGNFSYLHHGSCRGTHYA 265 >SB_27078| Best HMM Match : Kazal_2 (HMM E-Value=7.6e-07) Length = 54 Score = 32.7 bits (71), Expect = 0.20 Identities = 15/40 (37%), Positives = 22/40 (55%), Gaps = 3/40 (7%) Frame = -2 Query: 548 EYAPVCGSNGKTYANKCSLE---CTQKIIPSLKMEHDGEC 438 E PVCG++G Y ++C L C Q + LK++ G C Sbjct: 10 EAFPVCGTDGNDYPSRCKLRYQACMQNKLGLLKVKCGGSC 49 Score = 30.3 bits (65), Expect = 1.1 Identities = 13/37 (35%), Positives = 20/37 (54%) Frame = -2 Query: 410 PCICTREKGPVCGSDGVTYSNLCLLKCASLSKPSLSI 300 PC +E PVCG+DG Y + C L+ + + L + Sbjct: 4 PCGDEKEAFPVCGTDGNDYPSRCKLRYQACMQNKLGL 40 >SB_9563| Best HMM Match : Kazal_1 (HMM E-Value=1.7e-07) Length = 170 Score = 32.7 bits (71), Expect = 0.20 Identities = 22/68 (32%), Positives = 33/68 (48%), Gaps = 5/68 (7%) Frame = -2 Query: 455 EHDGECQGAKLASLHPCICTRE----KGPVCGSDGVTYSNLCLL-KCASLSKPSLSIEHT 291 ++ EC+ A A C+C R+ VC ++G T+ NLCLL K K + + H Sbjct: 86 DYFAECE-AFAADDAQCVCPRKCPSYVDQVCATNGETFDNLCLLKKHVCHIKGNFTFYHH 144 Query: 290 GPCDNNRV 267 G C R+ Sbjct: 145 GGCTGIRL 152 Score = 27.5 bits (58), Expect = 7.6 Identities = 14/39 (35%), Positives = 20/39 (51%), Gaps = 1/39 (2%) Frame = -2 Query: 536 VCGSNGKTYANKCSL-ECTQKIIPSLKMEHDGECQGAKL 423 VC +NG+T+ N C L + I + H G C G +L Sbjct: 114 VCATNGETFDNLCLLKKHVCHIKGNFTFYHHGGCTGIRL 152 >SB_45072| Best HMM Match : Kazal_2 (HMM E-Value=5.8e-06) Length = 361 Score = 31.5 bits (68), Expect = 0.47 Identities = 13/38 (34%), Positives = 20/38 (52%), Gaps = 1/38 (2%) Frame = -2 Query: 407 CICTREK-GPVCGSDGVTYSNLCLLKCASLSKPSLSIE 297 C C + + PVCG+D VTY C C + + ++ E Sbjct: 135 CACVKSQFNPVCGADDVTYFTPCHAGCRGIPEDTVGNE 172 >SB_25348| Best HMM Match : Kazal_1 (HMM E-Value=5.3e-09) Length = 73 Score = 31.1 bits (67), Expect = 0.62 Identities = 15/31 (48%), Positives = 16/31 (51%) Frame = -2 Query: 401 CTREKGPVCGSDGVTYSNLCLLKCASLSKPS 309 C PV GSDG Y N CLLK A+ S Sbjct: 32 CPEILKPVYGSDGKDYDNECLLKLAACKSKS 62 >SB_14008| Best HMM Match : Kazal_1 (HMM E-Value=5.3e-09) Length = 73 Score = 31.1 bits (67), Expect = 0.62 Identities = 15/31 (48%), Positives = 16/31 (51%) Frame = -2 Query: 401 CTREKGPVCGSDGVTYSNLCLLKCASLSKPS 309 C PV GSDG Y N CLLK A+ S Sbjct: 32 CPEILKPVYGSDGKDYDNECLLKLAACKSKS 62 >SB_22525| Best HMM Match : No HMM Matches (HMM E-Value=.) Length = 674 Score = 30.7 bits (66), Expect = 0.82 Identities = 16/31 (51%), Positives = 19/31 (61%), Gaps = 2/31 (6%) Frame = -2 Query: 407 CIC-TREKGPVCGSDGVTYSNLCLLKC-ASL 321 C C T + PVCG DGV+Y + C C ASL Sbjct: 464 CHCSTAQFRPVCGPDGVSYYSPCFAGCKASL 494 >SB_56344| Best HMM Match : Kazal_2 (HMM E-Value=1.5e-09) Length = 217 Score = 30.7 bits (66), Expect = 0.82 Identities = 14/46 (30%), Positives = 22/46 (47%), Gaps = 1/46 (2%) Frame = -2 Query: 410 PCICTREKGPVCGSDGVTYSNLCLLKC-ASLSKPSLSIEHTGPCDN 276 P C PVC G+ + N C L A + ++ +++ GPC N Sbjct: 38 PVSCPNTYEPVCSVYGIQFPNKCELHMFACIEGVNIGVKNKGPCVN 83 >SB_5272| Best HMM Match : No HMM Matches (HMM E-Value=.) Length = 259 Score = 30.3 bits (65), Expect = 1.1 Identities = 16/35 (45%), Positives = 19/35 (54%) Frame = -2 Query: 428 KLASLHPCICTREKGPVCGSDGVTYSNLCLLKCAS 324 K A + P C + PV GSDG Y N C LK A+ Sbjct: 55 KPACVCPPKCEKVYDPVYGSDGKNYDNECELKRAA 89 Score = 29.1 bits (62), Expect = 2.5 Identities = 11/19 (57%), Positives = 14/19 (73%) Frame = -2 Query: 545 YAPVCGSNGKTYANKCSLE 489 Y PV GS+GK Y N+C L+ Sbjct: 68 YDPVYGSDGKNYDNECELK 86 >SB_43077| Best HMM Match : No HMM Matches (HMM E-Value=.) Length = 1149 Score = 29.9 bits (64), Expect = 1.4 Identities = 20/63 (31%), Positives = 30/63 (47%), Gaps = 5/63 (7%) Frame = -2 Query: 455 EHDGECQGAKLASLHPCICTRE----KGPVCGSDGVTYSNLC-LLKCASLSKPSLSIEHT 291 ++ EC+ A A C+C R+ VC ++G T+ NLC L K K + + H Sbjct: 309 DYFAECE-AFAADDAQCVCPRKCPSYVDQVCATNGETFDNLCRLKKHVCHIKGNFTFYHH 367 Query: 290 GPC 282 G C Sbjct: 368 GSC 370 >SB_7030| Best HMM Match : Kazal_2 (HMM E-Value=4.6e-08) Length = 286 Score = 29.9 bits (64), Expect = 1.4 Identities = 20/63 (31%), Positives = 30/63 (47%), Gaps = 5/63 (7%) Frame = -2 Query: 455 EHDGECQGAKLASLHPCICTRE----KGPVCGSDGVTYSNLC-LLKCASLSKPSLSIEHT 291 ++ EC+ A A C+C R+ VC ++G T+ NLC L K K + + H Sbjct: 43 DYFAECE-AFAADDAQCVCPRKCPSYVDQVCATNGETFDNLCRLKKHVCHIKGNFTFYHH 101 Query: 290 GPC 282 G C Sbjct: 102 GSC 104 >SB_29074| Best HMM Match : Kazal_2 (HMM E-Value=3.3e-16) Length = 711 Score = 29.5 bits (63), Expect = 1.9 Identities = 14/36 (38%), Positives = 20/36 (55%) Frame = -2 Query: 389 KGPVCGSDGVTYSNLCLLKCASLSKPSLSIEHTGPC 282 K VCG DGV+Y + C + K S++ + GPC Sbjct: 402 KDMVCGEDGVSYPSEC-----GMIKHSVTFAYRGPC 432 Score = 28.7 bits (61), Expect = 3.3 Identities = 24/86 (27%), Positives = 38/86 (44%) Frame = -2 Query: 536 VCGSNGKTYANKCSLECTQKIIPSLKMEHDGECQGAKLASLHPCICTREKGPVCGSDGVT 357 VCG +G +Y ++C + I S+ + G C+ C + VC +DGVT Sbjct: 405 VCGEDGVSYPSECGM-----IKHSVTFAYRGPCRET---------CQQGNSQVCSTDGVT 450 Query: 356 YSNLCLLKCASLSKPSLSIEHTGPCD 279 + C ASL +++ G CD Sbjct: 451 LQSPC---HASLF--HRHVDYPGSCD 471 Score = 27.9 bits (59), Expect = 5.8 Identities = 16/44 (36%), Positives = 21/44 (47%), Gaps = 2/44 (4%) Frame = -2 Query: 401 CTREK-GPVCGSDGVTYSNLCLLK-CASLSKPSLSIEHTGPCDN 276 C +E PVCG D TY +LC + C + + GPC N Sbjct: 306 CDKEPVTPVCGPDWTTYRSLCHARFCGNYDIDEIV---QGPCQN 346 >SB_57638| Best HMM Match : F5_F8_type_C (HMM E-Value=1.7e-11) Length = 502 Score = 29.5 bits (63), Expect = 1.9 Identities = 13/28 (46%), Positives = 17/28 (60%), Gaps = 3/28 (10%) Frame = -2 Query: 407 CICTRE--KG-PVCGSDGVTYSNLCLLK 333 C C E +G PVC DG+ Y NLC ++ Sbjct: 406 CSCAMECPEGVPVCADDGLIYGNLCKMR 433 >SB_45722| Best HMM Match : No HMM Matches (HMM E-Value=.) Length = 1080 Score = 29.5 bits (63), Expect = 1.9 Identities = 16/56 (28%), Positives = 26/56 (46%), Gaps = 3/56 (5%) Frame = -2 Query: 428 KLASLHPCICTREKGPVCGSDGVTYSNLCLLKCASLSKPSLSI---EHTGPCDNNR 270 K+ H IC R + + G DG + S C C+S P S+ +H C+ ++ Sbjct: 596 KVDLCHQSICPRGRECIIGEDGNSTSCECSAVCSSEHAPVCSVFYTDHASECEMHK 651 >SB_27392| Best HMM Match : Kazal_1 (HMM E-Value=0.00072) Length = 196 Score = 29.1 bits (62), Expect = 2.5 Identities = 15/45 (33%), Positives = 23/45 (51%), Gaps = 1/45 (2%) Frame = -2 Query: 410 PCICTREKGPVCGSDGVTYSNLC-LLKCASLSKPSLSIEHTGPCD 279 P +C E+ VC + ++NLC L K A + + + GPCD Sbjct: 15 PQVCLDERITVCSVYVLEFNNLCELHKFACRYEIPIGVASMGPCD 59 >SB_18764| Best HMM Match : No HMM Matches (HMM E-Value=.) Length = 284 Score = 29.1 bits (62), Expect = 2.5 Identities = 17/51 (33%), Positives = 26/51 (50%), Gaps = 2/51 (3%) Frame = -3 Query: 328 RHCPNQA*AS--NTPVLAIITECRRWETKTIRTSILSQMRTEGRMFKIINI 182 RH QA A NTPV+A+ +T + IL + +++KIIN+ Sbjct: 230 RHHARQAVAQTLNTPVIAVYVSRHVKQTMNLHCKILPVINLHCKIYKIINL 280 >SB_2561| Best HMM Match : No HMM Matches (HMM E-Value=.) Length = 649 Score = 28.3 bits (60), Expect = 4.4 Identities = 9/18 (50%), Positives = 13/18 (72%) Frame = -3 Query: 499 VHWNAPKRLYRL*RWNMM 446 + W+AP +YRL WN+M Sbjct: 136 LEWSAPSEMYRLKAWNIM 153 >SB_20039| Best HMM Match : LRR_1 (HMM E-Value=0.0061) Length = 608 Score = 27.9 bits (59), Expect = 5.8 Identities = 16/47 (34%), Positives = 22/47 (46%) Frame = -3 Query: 367 TASLTAICAS*NARHCPNQA*ASNTPVLAIITECRRWETKTIRTSIL 227 T S+TA AS + R C + + +L + CRRW T IL Sbjct: 105 TRSVTATLASADVRRCFCRYAPPHDSLLRLAVVCRRWRDIIYNTPIL 151 >SB_38207| Best HMM Match : No HMM Matches (HMM E-Value=.) Length = 189 Score = 27.5 bits (58), Expect = 7.6 Identities = 23/83 (27%), Positives = 34/83 (40%), Gaps = 1/83 (1%) Frame = +1 Query: 211 QFASVTIYLFEWF*FPTAYTLLLSQGPVCSMLKLGLDSDAHFKRHRLL*VTPSLPQTGPF 390 ++ + LFE+ AY + S G +L +G S R ++L + P P Sbjct: 46 RYQGIMALLFEFADCCRAYLVSSSSG----LLIIGAKSSDKISRFKILSDAGTNPGYAPD 101 Query: 391 SRVH-IHGCKLASLAPWHSPSCS 456 SR G K A WH+ CS Sbjct: 102 SRPPPSEGAKRHEFATWHARGCS 124 >SB_28622| Best HMM Match : CcmD (HMM E-Value=0.55) Length = 1087 Score = 27.5 bits (58), Expect = 7.6 Identities = 9/29 (31%), Positives = 20/29 (68%) Frame = -3 Query: 256 ETKTIRTSILSQMRTEGRMFKIINIQFLM 170 E+K +R + ++++ +FK+IN +FL+ Sbjct: 709 ESKRLRKHVREDLKSDSEVFKLINTKFLV 737 >SB_16978| Best HMM Match : No HMM Matches (HMM E-Value=.) Length = 875 Score = 27.5 bits (58), Expect = 7.6 Identities = 9/22 (40%), Positives = 13/22 (59%) Frame = -2 Query: 548 EYAPVCGSNGKTYANKCSLECT 483 +Y+P+CG G Y + C CT Sbjct: 650 KYSPLCGPGGLNYFSPCFAGCT 671 Database: nematostella Posted date: Oct 22, 2007 1:22 PM Number of letters in database: 16,821,457 Number of sequences in database: 59,808 Lambda K H 0.318 0.134 0.401 Gapped Lambda K H 0.279 0.0580 0.190 Matrix: BLOSUM62 Gap Penalties: Existence: 9, Extension: 2 Number of Hits to DB: 16,351,856 Number of Sequences: 59808 Number of extensions: 330643 Number of successful extensions: 950 Number of sequences better than 10.0: 56 Number of HSP's better than 10.0 without gapping: 612 Number of HSP's successfully gapped in prelim test: 0 Number of HSP's that attempted gapping in prelim test: 0 Number of HSP's gapped (non-prelim): 898 length of database: 16,821,457 effective HSP length: 78 effective length of database: 12,156,433 effective search space used: 1264269032 frameshift window, decay const: 40, 0.1 T: 12 A: 40 X1: 16 ( 7.3 bits) X2: 37 (14.9 bits) X3: 62 (25.0 bits) S1: 41 (21.7 bits)
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