Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= I10A02NGRL0005_H23
(521 letters)
Database: nematostella
59,808 sequences; 16,821,457 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
SB_39834| Best HMM Match : Kazal_1 (HMM E-Value=0) 36 0.020
SB_18275| Best HMM Match : Kazal_1 (HMM E-Value=0) 36 0.027
SB_35516| Best HMM Match : Kazal_1 (HMM E-Value=0) 33 0.19
SB_7591| Best HMM Match : No HMM Matches (HMM E-Value=.) 33 0.19
SB_39831| Best HMM Match : Kazal_1 (HMM E-Value=2.4e-19) 32 0.25
SB_50468| Best HMM Match : Kazal_1 (HMM E-Value=1.3e-15) 32 0.33
SB_44384| Best HMM Match : Kazal_1 (HMM E-Value=1.4e-21) 32 0.33
SB_33374| Best HMM Match : No HMM Matches (HMM E-Value=.) 32 0.33
SB_15403| Best HMM Match : CH (HMM E-Value=0) 32 0.33
SB_41491| Best HMM Match : Kazal_1 (HMM E-Value=1.1e-12) 31 0.44
SB_33509| Best HMM Match : Kazal_1 (HMM E-Value=2.3e-26) 31 0.44
SB_6081| Best HMM Match : No HMM Matches (HMM E-Value=.) 31 0.44
SB_42767| Best HMM Match : Thyroglobulin_1 (HMM E-Value=0) 31 0.58
SB_135| Best HMM Match : Kazal_1 (HMM E-Value=2.9e-19) 31 0.58
SB_45072| Best HMM Match : Kazal_2 (HMM E-Value=5.8e-06) 30 1.0
SB_6080| Best HMM Match : No HMM Matches (HMM E-Value=.) 30 1.3
SB_26296| Best HMM Match : No HMM Matches (HMM E-Value=.) 29 2.3
SB_6686| Best HMM Match : Kazal_1 (HMM E-Value=0) 29 3.1
SB_15247| Best HMM Match : Hormone_5 (HMM E-Value=0.98) 28 4.1
SB_32965| Best HMM Match : Kazal_1 (HMM E-Value=3.4e-19) 28 4.1
SB_16461| Best HMM Match : No HMM Matches (HMM E-Value=.) 28 4.1
SB_11826| Best HMM Match : Kazal_1 (HMM E-Value=1.2e-16) 28 4.1
SB_37368| Best HMM Match : Kazal_1 (HMM E-Value=9.2e-09) 28 5.4
SB_21821| Best HMM Match : MRG (HMM E-Value=0) 28 5.4
SB_59196| Best HMM Match : DUF593 (HMM E-Value=1.7) 27 7.1
SB_33512| Best HMM Match : Kazal_1 (HMM E-Value=2.6e-20) 27 7.1
SB_46203| Best HMM Match : No HMM Matches (HMM E-Value=.) 27 9.4
SB_41585| Best HMM Match : No HMM Matches (HMM E-Value=.) 27 9.4
SB_58159| Best HMM Match : No HMM Matches (HMM E-Value=.) 27 9.4
SB_53017| Best HMM Match : Kazal_1 (HMM E-Value=0) 27 9.4
>SB_39834| Best HMM Match : Kazal_1 (HMM E-Value=0)
Length = 293
Score = 35.9 bits (79), Expect = 0.020
Identities = 15/26 (57%), Positives = 16/26 (61%)
Frame = +2
Query: 401 KCAENCISTPEYNPVCGSDDKTYQKP 478
+C C T E NPVCGSD KTY P
Sbjct: 117 RCMRRC--TKELNPVCGSDGKTYDNP 140
Score = 32.3 bits (70), Expect = 0.25
Identities = 14/27 (51%), Positives = 16/27 (59%)
Frame = +2
Query: 398 EKCAENCISTPEYNPVCGSDDKTYQKP 478
+KCA C Y PVCGSD+ TY P
Sbjct: 167 DKCAPIC--NKMYQPVCGSDNVTYSNP 191
Score = 27.5 bits (58), Expect = 7.1
Identities = 11/25 (44%), Positives = 15/25 (60%)
Frame = +2
Query: 395 IEKCAENCISTPEYNPVCGSDDKTY 469
++ C C + Y PVCG+D KTY
Sbjct: 41 VDPCVRPCPAI--YMPVCGTDGKTY 63
>SB_18275| Best HMM Match : Kazal_1 (HMM E-Value=0)
Length = 325
Score = 35.5 bits (78), Expect = 0.027
Identities = 17/30 (56%), Positives = 18/30 (60%)
Frame = +2
Query: 389 QTIEKCAENCISTPEYNPVCGSDDKTYQKP 478
Q + C E C T EY PVCGSD KTY P
Sbjct: 37 QPVCVCNEAC--TREYAPVCGSDGKTYPNP 64
Score = 31.5 bits (68), Expect = 0.44
Identities = 13/23 (56%), Positives = 17/23 (73%)
Frame = +2
Query: 401 KCAENCISTPEYNPVCGSDDKTY 469
+C + C T +Y PVCGSD+KTY
Sbjct: 195 ECPKVC--TLDYTPVCGSDNKTY 215
Score = 28.7 bits (61), Expect = 3.1
Identities = 13/31 (41%), Positives = 18/31 (58%)
Frame = +2
Query: 401 KCAENCISTPEYNPVCGSDDKTYQKPGKTIL 493
+C + C T EY P CG+D TY P + +L
Sbjct: 278 ECPKAC--TREYKPACGTDGNTY--PNRCVL 304
Score = 27.5 bits (58), Expect = 7.1
Identities = 12/23 (52%), Positives = 14/23 (60%)
Frame = +2
Query: 401 KCAENCISTPEYNPVCGSDDKTY 469
+C C T E PVCG+D KTY
Sbjct: 117 ECPRAC--TRELMPVCGTDQKTY 137
>SB_35516| Best HMM Match : Kazal_1 (HMM E-Value=0)
Length = 320
Score = 32.7 bits (71), Expect = 0.19
Identities = 14/22 (63%), Positives = 16/22 (72%)
Frame = +2
Query: 404 CAENCISTPEYNPVCGSDDKTY 469
C ENC ST + PVCGSD+ TY
Sbjct: 275 CPENCSSTVD--PVCGSDNNTY 294
Score = 31.5 bits (68), Expect = 0.44
Identities = 13/22 (59%), Positives = 16/22 (72%)
Frame = +2
Query: 404 CAENCISTPEYNPVCGSDDKTY 469
C ENC ST + PVCG+D+ TY
Sbjct: 161 CPENCSSTVD--PVCGTDNNTY 180
>SB_7591| Best HMM Match : No HMM Matches (HMM E-Value=.)
Length = 3261
Score = 32.7 bits (71), Expect = 0.19
Identities = 14/22 (63%), Positives = 16/22 (72%)
Frame = +2
Query: 404 CAENCISTPEYNPVCGSDDKTY 469
C ENC ST + PVCGSD+ TY
Sbjct: 1206 CPENCSSTVD--PVCGSDNNTY 1225
Score = 31.5 bits (68), Expect = 0.44
Identities = 13/22 (59%), Positives = 16/22 (72%)
Frame = +2
Query: 404 CAENCISTPEYNPVCGSDDKTY 469
C ENC ST + PVCG+D+ TY
Sbjct: 1135 CPENCSSTVD--PVCGTDNNTY 1154
Score = 27.1 bits (57), Expect = 9.4
Identities = 11/23 (47%), Positives = 15/23 (65%)
Frame = +2
Query: 401 KCAENCISTPEYNPVCGSDDKTY 469
+C+E+C T PVCGSD+ Y
Sbjct: 1372 ECSEDCPKT--LKPVCGSDNNDY 1392
>SB_39831| Best HMM Match : Kazal_1 (HMM E-Value=2.4e-19)
Length = 173
Score = 32.3 bits (70), Expect = 0.25
Identities = 14/27 (51%), Positives = 16/27 (59%)
Frame = +2
Query: 398 EKCAENCISTPEYNPVCGSDDKTYQKP 478
+KCA C Y PVCGSD+ TY P
Sbjct: 24 DKCAPIC--NKMYQPVCGSDNVTYSNP 48
>SB_50468| Best HMM Match : Kazal_1 (HMM E-Value=1.3e-15)
Length = 1724
Score = 31.9 bits (69), Expect = 0.33
Identities = 15/27 (55%), Positives = 17/27 (62%)
Frame = +2
Query: 389 QTIEKCAENCISTPEYNPVCGSDDKTY 469
Q + +C C T EY PVCGSD KTY
Sbjct: 42 QPVCECPMAC--TREYAPVCGSDGKTY 66
>SB_44384| Best HMM Match : Kazal_1 (HMM E-Value=1.4e-21)
Length = 85
Score = 31.9 bits (69), Expect = 0.33
Identities = 14/27 (51%), Positives = 16/27 (59%)
Frame = +2
Query: 398 EKCAENCISTPEYNPVCGSDDKTYQKP 478
+KCA C Y PVCGSD+ TY P
Sbjct: 38 DKCAPICPKI--YRPVCGSDNVTYSNP 62
>SB_33374| Best HMM Match : No HMM Matches (HMM E-Value=.)
Length = 4475
Score = 31.9 bits (69), Expect = 0.33
Identities = 14/23 (60%), Positives = 17/23 (73%)
Frame = +2
Query: 404 CAENCISTPEYNPVCGSDDKTYQ 472
C +NC ST + PVCGSD KTY+
Sbjct: 3970 CNKNCPSTSK--PVCGSDGKTYK 3990
Score = 29.9 bits (64), Expect = 1.3
Identities = 11/24 (45%), Positives = 16/24 (66%)
Frame = +2
Query: 401 KCAENCISTPEYNPVCGSDDKTYQ 472
+C C+ P+ PVCG+D KTY+
Sbjct: 4236 ECPSRCL--PDKEPVCGADGKTYR 4257
>SB_15403| Best HMM Match : CH (HMM E-Value=0)
Length = 1907
Score = 31.9 bits (69), Expect = 0.33
Identities = 13/23 (56%), Positives = 14/23 (60%)
Frame = +2
Query: 401 KCAENCISTPEYNPVCGSDDKTY 469
KC + T EY PVCGSD TY
Sbjct: 721 KCVCSAACTREYAPVCGSDGNTY 743
Score = 29.5 bits (63), Expect = 1.8
Identities = 10/23 (43%), Positives = 15/23 (65%)
Frame = +2
Query: 401 KCAENCISTPEYNPVCGSDDKTY 469
+C + P Y+P+CG+D KTY
Sbjct: 1232 RCECDLRPDPAYDPICGTDGKTY 1254
>SB_41491| Best HMM Match : Kazal_1 (HMM E-Value=1.1e-12)
Length = 77
Score = 31.5 bits (68), Expect = 0.44
Identities = 13/24 (54%), Positives = 18/24 (75%), Gaps = 1/24 (4%)
Frame = +2
Query: 401 KCAEN-CISTPEYNPVCGSDDKTY 469
KC ++ + T +Y+PVCGSD KTY
Sbjct: 24 KCDDSPTLCTLQYDPVCGSDGKTY 47
>SB_33509| Best HMM Match : Kazal_1 (HMM E-Value=2.3e-26)
Length = 143
Score = 31.5 bits (68), Expect = 0.44
Identities = 13/22 (59%), Positives = 16/22 (72%)
Frame = +2
Query: 404 CAENCISTPEYNPVCGSDDKTY 469
C ENC ST + PVCG+D+ TY
Sbjct: 27 CPENCSSTVD--PVCGTDNNTY 46
>SB_6081| Best HMM Match : No HMM Matches (HMM E-Value=.)
Length = 56
Score = 31.5 bits (68), Expect = 0.44
Identities = 11/15 (73%), Positives = 13/15 (86%)
Frame = +2
Query: 425 TPEYNPVCGSDDKTY 469
T +YNPVCGSD +TY
Sbjct: 15 TADYNPVCGSDGRTY 29
>SB_42767| Best HMM Match : Thyroglobulin_1 (HMM E-Value=0)
Length = 6725
Score = 31.1 bits (67), Expect = 0.58
Identities = 13/22 (59%), Positives = 16/22 (72%)
Frame = +2
Query: 404 CAENCISTPEYNPVCGSDDKTY 469
C+ I T EY+P+CGSD KTY
Sbjct: 5152 CSCPDICTFEYSPLCGSDGKTY 5173
Score = 30.7 bits (66), Expect = 0.76
Identities = 12/22 (54%), Positives = 15/22 (68%)
Frame = +2
Query: 404 CAENCISTPEYNPVCGSDDKTY 469
C N I T EY PVCG+D ++Y
Sbjct: 5222 CTCNSICTLEYAPVCGTDGQSY 5243
Score = 29.1 bits (62), Expect = 2.3
Identities = 13/19 (68%), Positives = 13/19 (68%), Gaps = 1/19 (5%)
Frame = +2
Query: 416 CISTPEYN-PVCGSDDKTY 469
C S P N PVCGSD KTY
Sbjct: 5621 CQSCPSINKPVCGSDGKTY 5639
Score = 27.1 bits (57), Expect = 9.4
Identities = 11/19 (57%), Positives = 13/19 (68%), Gaps = 1/19 (5%)
Frame = +2
Query: 416 CISTPEY-NPVCGSDDKTY 469
C+S P +PVCGSD K Y
Sbjct: 5790 CLSCPNILDPVCGSDGKNY 5808
>SB_135| Best HMM Match : Kazal_1 (HMM E-Value=2.9e-19)
Length = 92
Score = 31.1 bits (67), Expect = 0.58
Identities = 13/25 (52%), Positives = 15/25 (60%)
Frame = +2
Query: 395 IEKCAENCISTPEYNPVCGSDDKTY 469
I +C N T Y PVCG+D KTY
Sbjct: 34 IVRCVCNRACTKIYRPVCGTDGKTY 58
>SB_45072| Best HMM Match : Kazal_2 (HMM E-Value=5.8e-06)
Length = 361
Score = 30.3 bits (65), Expect = 1.0
Identities = 11/21 (52%), Positives = 16/21 (76%)
Frame = +2
Query: 416 CISTPEYNPVCGSDDKTYQKP 478
C+ + ++NPVCG+DD TY P
Sbjct: 137 CVKS-QFNPVCGADDVTYFTP 156
>SB_6080| Best HMM Match : No HMM Matches (HMM E-Value=.)
Length = 2101
Score = 29.9 bits (64), Expect = 1.3
Identities = 14/23 (60%), Positives = 15/23 (65%)
Frame = +2
Query: 401 KCAENCISTPEYNPVCGSDDKTY 469
KC C T EY PVCG+D KTY
Sbjct: 1294 KCPIFC--TYEYMPVCGTDGKTY 1314
Score = 29.5 bits (63), Expect = 1.8
Identities = 11/23 (47%), Positives = 14/23 (60%)
Frame = +2
Query: 401 KCAENCISTPEYNPVCGSDDKTY 469
+C ++T EY PVC SD K Y
Sbjct: 1966 ECVCRTVTTLEYRPVCASDGKIY 1988
Score = 28.7 bits (61), Expect = 3.1
Identities = 12/23 (52%), Positives = 15/23 (65%)
Frame = +2
Query: 401 KCAENCISTPEYNPVCGSDDKTY 469
KC + + T +Y PVC SD KTY
Sbjct: 1522 KCRQ--MMTADYTPVCASDGKTY 1542
Score = 27.5 bits (58), Expect = 7.1
Identities = 12/24 (50%), Positives = 16/24 (66%)
Frame = +2
Query: 401 KCAENCISTPEYNPVCGSDDKTYQ 472
KC + I +P +PVCGSD K Y+
Sbjct: 1753 KCPPS-ICSPVISPVCGSDGKIYK 1775
>SB_26296| Best HMM Match : No HMM Matches (HMM E-Value=.)
Length = 73
Score = 29.1 bits (62), Expect = 2.3
Identities = 15/45 (33%), Positives = 22/45 (48%)
Frame = +2
Query: 92 ALLILGFIASQATCMNIRYKRQIENNANLFIDKNGWNKSQDGNRP 226
A +I GF+ + C +RY Q+ N +N W+ S NRP
Sbjct: 6 ATIIRGFLKFRIICEKVRYFTQLRACYN--PQQNKWDTSHTNNRP 48
>SB_6686| Best HMM Match : Kazal_1 (HMM E-Value=0)
Length = 2411
Score = 28.7 bits (61), Expect = 3.1
Identities = 12/23 (52%), Positives = 15/23 (65%)
Frame = +2
Query: 404 CAENCISTPEYNPVCGSDDKTYQ 472
C NC S +++PVCG D TYQ
Sbjct: 579 CPTNCPS--DWDPVCGDDGVTYQ 599
Score = 27.9 bits (59), Expect = 5.4
Identities = 11/18 (61%), Positives = 13/18 (72%)
Frame = +2
Query: 431 EYNPVCGSDDKTYQKPGK 484
E +PVCGSD KTY+ K
Sbjct: 516 EASPVCGSDGKTYENECK 533
Score = 27.1 bits (57), Expect = 9.4
Identities = 11/23 (47%), Positives = 13/23 (56%)
Frame = +2
Query: 401 KCAENCISTPEYNPVCGSDDKTY 469
KC+ P PVCGSD K+Y
Sbjct: 1679 KCSCPIYCPPSGQPVCGSDGKSY 1701
>SB_15247| Best HMM Match : Hormone_5 (HMM E-Value=0.98)
Length = 997
Score = 28.3 bits (60), Expect = 4.1
Identities = 24/68 (35%), Positives = 31/68 (45%)
Frame = +2
Query: 104 LGFIASQATCMNIRYKRQIENNANLFIDKNGWNKSQDGNRPEWIPIQNGYRIQYPLDNNY 283
LG I SQA NIR Q N +L + N + P+Q GY+ PL +NY
Sbjct: 612 LGQITSQAIGSNIR---QDVANVSLPLQMPISNPKTSVPQGGATPMQFGYQGYGPLQHNY 668
Query: 284 NFIAFIFP 307
+ IFP
Sbjct: 669 GDMNTIFP 676
>SB_32965| Best HMM Match : Kazal_1 (HMM E-Value=3.4e-19)
Length = 69
Score = 28.3 bits (60), Expect = 4.1
Identities = 13/26 (50%), Positives = 16/26 (61%), Gaps = 1/26 (3%)
Frame = +2
Query: 395 IEKCAENCISTPEYN-PVCGSDDKTY 469
++KC C P N PVCG+D KTY
Sbjct: 21 VDKCVRPC---PAINDPVCGTDGKTY 43
>SB_16461| Best HMM Match : No HMM Matches (HMM E-Value=.)
Length = 173
Score = 28.3 bits (60), Expect = 4.1
Identities = 9/37 (24%), Positives = 22/37 (59%), Gaps = 4/37 (10%)
Frame = +3
Query: 15 LYLYLCYKICHINYFYY----YNLKWISCARFLYWVL 113
++L+ +CH+NY Y+ +++ W+ ++Y V+
Sbjct: 121 IWLFHVSLLCHVNYMYHVIWLFHVSWLCHVNYMYHVI 157
>SB_11826| Best HMM Match : Kazal_1 (HMM E-Value=1.2e-16)
Length = 98
Score = 28.3 bits (60), Expect = 4.1
Identities = 11/25 (44%), Positives = 15/25 (60%)
Frame = +2
Query: 395 IEKCAENCISTPEYNPVCGSDDKTY 469
I +C N Y+P+CG+D KTY
Sbjct: 34 IARCVCNRACKKIYSPMCGTDGKTY 58
>SB_37368| Best HMM Match : Kazal_1 (HMM E-Value=9.2e-09)
Length = 68
Score = 27.9 bits (59), Expect = 5.4
Identities = 11/22 (50%), Positives = 13/22 (59%)
Frame = +2
Query: 404 CAENCISTPEYNPVCGSDDKTY 469
C+ +C PVCGSDD TY
Sbjct: 8 CSFSCDDGFHQTPVCGSDDVTY 29
>SB_21821| Best HMM Match : MRG (HMM E-Value=0)
Length = 292
Score = 27.9 bits (59), Expect = 5.4
Identities = 16/44 (36%), Positives = 22/44 (50%)
Frame = +2
Query: 107 GFIASQATCMNIRYKRQIENNANLFIDKNGWNKSQDGNRPEWIP 238
G + +A C+ + K E A I NGWNK+ D EW+P
Sbjct: 18 GPLIYEAKCIRGQLK---EKTARYLIHYNGWNKNWD----EWVP 54
>SB_59196| Best HMM Match : DUF593 (HMM E-Value=1.7)
Length = 1376
Score = 27.5 bits (58), Expect = 7.1
Identities = 8/15 (53%), Positives = 11/15 (73%)
Frame = +2
Query: 404 CAENCISTPEYNPVC 448
C +CISTP Y+ +C
Sbjct: 1196 CVHSCISTPRYDQIC 1210
>SB_33512| Best HMM Match : Kazal_1 (HMM E-Value=2.6e-20)
Length = 87
Score = 27.5 bits (58), Expect = 7.1
Identities = 12/19 (63%), Positives = 14/19 (73%)
Frame = +2
Query: 413 NCISTPEYNPVCGSDDKTY 469
NC ST + PVCGSD+ TY
Sbjct: 2 NCSSTVD--PVCGSDNNTY 18
>SB_46203| Best HMM Match : No HMM Matches (HMM E-Value=.)
Length = 557
Score = 27.1 bits (57), Expect = 9.4
Identities = 11/19 (57%), Positives = 13/19 (68%), Gaps = 1/19 (5%)
Frame = +2
Query: 416 CISTPEY-NPVCGSDDKTY 469
C+S P +PVCGSD K Y
Sbjct: 111 CLSCPNILDPVCGSDGKNY 129
Score = 27.1 bits (57), Expect = 9.4
Identities = 11/19 (57%), Positives = 13/19 (68%), Gaps = 1/19 (5%)
Frame = +2
Query: 416 CISTPEY-NPVCGSDDKTY 469
C+S P +PVCGSD K Y
Sbjct: 274 CLSCPNMLDPVCGSDGKNY 292
>SB_41585| Best HMM Match : No HMM Matches (HMM E-Value=.)
Length = 118
Score = 27.1 bits (57), Expect = 9.4
Identities = 12/30 (40%), Positives = 18/30 (60%)
Frame = +3
Query: 357 HQLLALVEHHDKQLRNARRIAFQHQNTTPC 446
H L AL +++R RRI+++ QNT C
Sbjct: 84 HSLPALTFESARKVRQYRRISWEGQNTQTC 113
>SB_58159| Best HMM Match : No HMM Matches (HMM E-Value=.)
Length = 443
Score = 27.1 bits (57), Expect = 9.4
Identities = 12/23 (52%), Positives = 16/23 (69%)
Frame = +2
Query: 401 KCAENCISTPEYNPVCGSDDKTY 469
+C E C S E +PVCG+D +TY
Sbjct: 205 RCHEPCPS--EASPVCGTDMRTY 225
>SB_53017| Best HMM Match : Kazal_1 (HMM E-Value=0)
Length = 1488
Score = 27.1 bits (57), Expect = 9.4
Identities = 11/22 (50%), Positives = 13/22 (59%)
Frame = +2
Query: 404 CAENCISTPEYNPVCGSDDKTY 469
C +C T Y+PVCG D TY
Sbjct: 252 CPSDCSHT--YSPVCGGDKTTY 271
Database: nematostella
Posted date: Oct 22, 2007 1:22 PM
Number of letters in database: 16,821,457
Number of sequences in database: 59,808
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 17,517,322
Number of Sequences: 59808
Number of extensions: 364554
Number of successful extensions: 1007
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 828
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 983
length of database: 16,821,457
effective HSP length: 77
effective length of database: 12,216,241
effective search space used: 1172759136
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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