Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= I10A02NGRL0005_E24
(652 letters)
Database: human
237,096 sequences; 76,859,062 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
X04412-1|CAA28000.1| 782|Homo sapiens plasma gelsolin protein. 223 4e-58
BC026033-1|AAH26033.1| 782|Homo sapiens gelsolin (amyloidosis, ... 223 4e-58
AL513122-6|CAM20459.1| 731|Homo sapiens gelsolin (amyloidosis, ... 223 4e-58
AL513122-5|CAI14415.1| 260|Homo sapiens gelsolin (amyloidosis, ... 223 4e-58
AL513122-4|CAI14414.1| 228|Homo sapiens gelsolin (amyloidosis, ... 223 4e-58
AL513122-3|CAI14413.1| 782|Homo sapiens gelsolin (amyloidosis, ... 223 4e-58
AF276507-1|AAK60494.1| 715|Homo sapiens scinderin protein. 198 2e-50
AC005281-1|AAD15423.1| 527|Homo sapiens WUGSC:H_DJ0722F20.1 pro... 198 2e-50
AB067492-1|BAB67798.1| 626|Homo sapiens KIAA1905 protein protein. 198 2e-50
BC021090-1|AAH21090.1| 715|Homo sapiens SCIN protein protein. 197 2e-50
AK075123-1|BAC11416.1| 715|Homo sapiens protein ( Homo sapiens ... 197 3e-50
AF041449-1|AAC25051.1| 819|Homo sapiens advillin protein. 176 5e-44
X12901-1|CAA31386.1| 827|Homo sapiens protein ( Human mRNA for ... 175 1e-43
BC017303-1|AAH17303.1| 421|Homo sapiens VIL1 protein protein. 175 1e-43
AK223398-1|BAD97118.1| 827|Homo sapiens villin 1 variant protein. 175 1e-43
BC111730-1|AAI11731.1| 812|Homo sapiens AVIL protein protein. 166 5e-41
M94345-1|AAA59570.1| 348|Homo sapiens macrophage capping protei... 165 2e-40
BC014549-1|AAH14549.1| 348|Homo sapiens capping protein (actin ... 165 2e-40
BC000728-1|AAH00728.1| 348|Homo sapiens capping protein (actin ... 165 2e-40
AC062037-3|AAY24128.1| 348|Homo sapiens unknown protein. 165 2e-40
U80184-1|AAC02796.1| 1269|Homo sapiens FLII protein. 144 2e-34
U01184-1|AAC03568.1| 1268|Homo sapiens flightless-I homolog prot... 144 2e-34
BC025300-1|AAH25300.1| 1269|Homo sapiens flightless I homolog (D... 144 2e-34
AB208864-1|BAD92101.1| 1101|Homo sapiens flightless I homolog va... 144 2e-34
U12026-1|AAA92670.1| 172|Homo sapiens Cap-G protein. 137 3e-32
AL513122-7|CAI14416.1| 485|Homo sapiens gelsolin (amyloidosis, ... 97 6e-20
AK075198-1|BAC11465.1| 396|Homo sapiens protein ( Homo sapiens ... 92 1e-18
AK027778-1|BAB55361.1| 468|Homo sapiens protein ( Homo sapiens ... 92 1e-18
X07066-1|CAA30102.1| 69|Homo sapiens protein ( Human gene for ... 78 3e-14
D88154-1|BAA21668.1| 686|Homo sapiens villin-like protein protein. 73 7e-13
BC004300-1|AAH04300.1| 672|Homo sapiens VILL protein protein. 73 7e-13
BC000243-1|AAH00243.1| 686|Homo sapiens VILL protein protein. 73 7e-13
BC075797-1|AAH75797.1| 85|Homo sapiens Unknown (protein for MG... 65 2e-10
BC017491-1|AAH17491.1| 285|Homo sapiens Similar to gelsolin (am... 64 3e-10
AL160060-2|CAH71300.1| 2214|Homo sapiens supervillin protein. 55 3e-07
AL160060-1|CAH71301.1| 1788|Homo sapiens supervillin protein. 55 3e-07
AL158167-3|CAI15237.1| 2214|Homo sapiens supervillin protein. 55 3e-07
AL158167-2|CAI15236.1| 1788|Homo sapiens supervillin protein. 55 3e-07
AF109135-1|AAD14682.1| 2214|Homo sapiens archvillin protein. 55 3e-07
AF051851-1|AAC64696.1| 1788|Homo sapiens supervillin protein. 55 3e-07
AF051850-1|AAC64695.1| 1788|Homo sapiens supervillin protein. 55 3e-07
Y08612-1|CAA69904.1| 741|Homo sapiens 88kDa nuclear pore comple... 33 1.2
BC000335-1|AAH00335.1| 741|Homo sapiens nucleoporin 88kDa protein. 33 1.2
>X04412-1|CAA28000.1| 782|Homo sapiens plasma gelsolin protein.
Length = 782
Score = 223 bits (545), Expect = 4e-58
Identities = 102/205 (49%), Positives = 136/205 (66%)
Frame = +2
Query: 20 HPAFANAGRQAGVEIWRIQNFEPVAVQSKDFGKFYKGDSYIILKTTSDKRNNLSWDIHYW 199
HP F AG++ G++IWR++ F+ V V + +G F+ GD+Y+ILKT + NL +D+HYW
Sbjct: 56 HPEFLKAGKEPGLQIWRVEKFDLVPVPTNLYGDFFTGDAYVILKTVQLRNGNLQYDLHYW 115
Query: 200 IGSETSQDEAGAAAILTVGLDDKFGGAAVQHREAMGHESNHFLQYFTSALQYLDGGNPSG 379
+G+E SQDE+GAAAI TV LDD G AVQHRE G ES FL YF S L+Y GG SG
Sbjct: 116 LGNECSQDESGAAAIFTVQLDDYLNGRAVQHREVQGFESATFLGYFKSGLKYKKGGVASG 175
Query: 380 FNHVVTNPGAEKRMFQVKGKRNVRVRQVDPLISSMNKGDCFILDINNDIYVYVGERTKNV 559
F HVV N +R+FQVKG+R VR +V S N GDCFILD+ N+I+ + G +
Sbjct: 176 FKHVVPNEVVVQRLFQVKGRRVVRATEVPVSWESFNNGDCFILDLGNNIHQWCGSNSNRY 235
Query: 560 EKLKAISMANQIRDQDHNGRGRVEI 634
E+LKA ++ IRD + +GR RV +
Sbjct: 236 ERLKATQVSKGIRDNERSGRARVHV 260
Score = 96.7 bits (230), Expect = 6e-20
Identities = 62/184 (33%), Positives = 87/184 (47%), Gaps = 2/184 (1%)
Frame = +2
Query: 59 EIWRIQNFEPVAVQSKDFGKFYKGDSYIILKTTSDKRNNLSWDIHYWIGSETSQDEAGAA 238
+IWRI+ V V +G+FY GDSYIIL I+ W G++++QDE A+
Sbjct: 448 QIWRIEGSNKVPVDPATYGQFYGGDSYIILYNYRHGGRQ-GQIIYNWQGAQSTQDEVAAS 506
Query: 239 AILTVGLDDKFGGAAVQHREAMGHESNHFLQYFTSALQYLDGGNPSGFNHVVTNPGAEKR 418
AILT LD++ GG VQ R G E H + F + G S T P A R
Sbjct: 507 AILTAQLDEELGGTPVQSRVVQGKEPAHLMSLFGGKPMIIYKGGTSR-EGGQTAP-ASTR 564
Query: 419 MFQVKGKRNVRVRQVD--PLISSMNKGDCFILDINNDIYVYVGERTKNVEKLKAISMANQ 592
+FQV+ R V+ P ++N D F+L + Y++VG EK A +
Sbjct: 565 LFQVRANSAGATRAVEVLPKAGALNSNDAFVLKTPSAAYLWVGTGASEAEKTGAQELLRV 624
Query: 593 IRDQ 604
+R Q
Sbjct: 625 LRAQ 628
Score = 37.9 bits (84), Expect = 0.031
Identities = 42/163 (25%), Positives = 66/163 (40%), Gaps = 8/163 (4%)
Frame = +2
Query: 173 NLSWDIHYWIGSETSQDEAGAAAILTVGL-DDKFGGAAVQHREAMGHESNHFLQYFTSAL 349
+L +IH W GS +++ E A ++ G+ D++ G A H G E LQ
Sbjct: 219 DLGNNIHQWCGSNSNRYERLKATQVSKGIRDNERSGRARVHVSEEGTEPEAMLQVL-GPK 277
Query: 350 QYLDGGNPSGFNHVVTNPGAEKRMFQVKGKRNVRVRQV---DPLISSMNKG-DCFILDIN 517
L G N K G + V V +P K DCFILD
Sbjct: 278 PALPAGTEDTAKEDAANRKLAKLYKVSNGAGTMSVSLVADENPFAQGALKSEDCFILDHG 337
Query: 518 ND--IYVYVGERTKNVEKLKAISMANQ-IRDQDHNGRGRVEII 637
D I+V+ G++ E+ A+ A+ I D+ + +V ++
Sbjct: 338 KDGKIFVWKGKQANTEERKAALKTASDFITKMDYPKQTQVSVL 380
>BC026033-1|AAH26033.1| 782|Homo sapiens gelsolin (amyloidosis,
Finnish type) protein.
Length = 782
Score = 223 bits (545), Expect = 4e-58
Identities = 102/205 (49%), Positives = 136/205 (66%)
Frame = +2
Query: 20 HPAFANAGRQAGVEIWRIQNFEPVAVQSKDFGKFYKGDSYIILKTTSDKRNNLSWDIHYW 199
HP F AG++ G++IWR++ F+ V V + +G F+ GD+Y+ILKT + NL +D+HYW
Sbjct: 56 HPEFLKAGKEPGLQIWRVEKFDLVPVPTNLYGDFFTGDAYVILKTVQLRNGNLQYDLHYW 115
Query: 200 IGSETSQDEAGAAAILTVGLDDKFGGAAVQHREAMGHESNHFLQYFTSALQYLDGGNPSG 379
+G+E SQDE+GAAAI TV LDD G AVQHRE G ES FL YF S L+Y GG SG
Sbjct: 116 LGNECSQDESGAAAIFTVQLDDYLNGRAVQHREVQGFESATFLGYFKSGLKYKKGGVASG 175
Query: 380 FNHVVTNPGAEKRMFQVKGKRNVRVRQVDPLISSMNKGDCFILDINNDIYVYVGERTKNV 559
F HVV N +R+FQVKG+R VR +V S N GDCFILD+ N+I+ + G +
Sbjct: 176 FKHVVPNEVVVQRLFQVKGRRVVRATEVPVSWESFNNGDCFILDLGNNIHQWCGSNSNRY 235
Query: 560 EKLKAISMANQIRDQDHNGRGRVEI 634
E+LKA ++ IRD + +GR RV +
Sbjct: 236 ERLKATQVSKGIRDNERSGRARVHV 260
Score = 96.7 bits (230), Expect = 6e-20
Identities = 62/184 (33%), Positives = 87/184 (47%), Gaps = 2/184 (1%)
Frame = +2
Query: 59 EIWRIQNFEPVAVQSKDFGKFYKGDSYIILKTTSDKRNNLSWDIHYWIGSETSQDEAGAA 238
+IWRI+ V V +G+FY GDSYIIL I+ W G++++QDE A+
Sbjct: 448 QIWRIEGSNKVPVDPATYGQFYGGDSYIILYNYRHGGRQ-GQIIYNWQGAQSTQDEVAAS 506
Query: 239 AILTVGLDDKFGGAAVQHREAMGHESNHFLQYFTSALQYLDGGNPSGFNHVVTNPGAEKR 418
AILT LD++ GG VQ R G E H + F + G S T P A R
Sbjct: 507 AILTAQLDEELGGTPVQSRVVQGKEPAHLMSLFGGKPMIIYKGGTSR-EGGQTAP-ASTR 564
Query: 419 MFQVKGKRNVRVRQVD--PLISSMNKGDCFILDINNDIYVYVGERTKNVEKLKAISMANQ 592
+FQV+ R V+ P ++N D F+L + Y++VG EK A +
Sbjct: 565 LFQVRANSAGATRAVEVLPKAGALNSNDAFVLKTPSAAYLWVGTGASEAEKTGAQELLRV 624
Query: 593 IRDQ 604
+R Q
Sbjct: 625 LRAQ 628
Score = 37.9 bits (84), Expect = 0.031
Identities = 42/163 (25%), Positives = 66/163 (40%), Gaps = 8/163 (4%)
Frame = +2
Query: 173 NLSWDIHYWIGSETSQDEAGAAAILTVGL-DDKFGGAAVQHREAMGHESNHFLQYFTSAL 349
+L +IH W GS +++ E A ++ G+ D++ G A H G E LQ
Sbjct: 219 DLGNNIHQWCGSNSNRYERLKATQVSKGIRDNERSGRARVHVSEEGTEPEAMLQVL-GPK 277
Query: 350 QYLDGGNPSGFNHVVTNPGAEKRMFQVKGKRNVRVRQV---DPLISSMNKG-DCFILDIN 517
L G N K G + V V +P K DCFILD
Sbjct: 278 PALPAGTEDTAKEDAANRKLAKLYKVSNGAGTMSVSLVADENPFAQGALKSEDCFILDHG 337
Query: 518 ND--IYVYVGERTKNVEKLKAISMANQ-IRDQDHNGRGRVEII 637
D I+V+ G++ E+ A+ A+ I D+ + +V ++
Sbjct: 338 KDGKIFVWKGKQANTEERKAALKTASDFITKMDYPKQTQVSVL 380
>AL513122-6|CAM20459.1| 731|Homo sapiens gelsolin (amyloidosis,
Finnish type) protein.
Length = 731
Score = 223 bits (545), Expect = 4e-58
Identities = 102/205 (49%), Positives = 136/205 (66%)
Frame = +2
Query: 20 HPAFANAGRQAGVEIWRIQNFEPVAVQSKDFGKFYKGDSYIILKTTSDKRNNLSWDIHYW 199
HP F AG++ G++IWR++ F+ V V + +G F+ GD+Y+ILKT + NL +D+HYW
Sbjct: 5 HPEFLKAGKEPGLQIWRVEKFDLVPVPTNLYGDFFTGDAYVILKTVQLRNGNLQYDLHYW 64
Query: 200 IGSETSQDEAGAAAILTVGLDDKFGGAAVQHREAMGHESNHFLQYFTSALQYLDGGNPSG 379
+G+E SQDE+GAAAI TV LDD G AVQHRE G ES FL YF S L+Y GG SG
Sbjct: 65 LGNECSQDESGAAAIFTVQLDDYLNGRAVQHREVQGFESATFLGYFKSGLKYKKGGVASG 124
Query: 380 FNHVVTNPGAEKRMFQVKGKRNVRVRQVDPLISSMNKGDCFILDINNDIYVYVGERTKNV 559
F HVV N +R+FQVKG+R VR +V S N GDCFILD+ N+I+ + G +
Sbjct: 125 FKHVVPNEVVVQRLFQVKGRRVVRATEVPVSWESFNNGDCFILDLGNNIHQWCGSNSNRY 184
Query: 560 EKLKAISMANQIRDQDHNGRGRVEI 634
E+LKA ++ IRD + +GR RV +
Sbjct: 185 ERLKATQVSKGIRDNERSGRARVHV 209
Score = 96.7 bits (230), Expect = 6e-20
Identities = 62/184 (33%), Positives = 87/184 (47%), Gaps = 2/184 (1%)
Frame = +2
Query: 59 EIWRIQNFEPVAVQSKDFGKFYKGDSYIILKTTSDKRNNLSWDIHYWIGSETSQDEAGAA 238
+IWRI+ V V +G+FY GDSYIIL I+ W G++++QDE A+
Sbjct: 397 QIWRIEGSNKVPVDPATYGQFYGGDSYIILYNYRHGGRQ-GQIIYNWQGAQSTQDEVAAS 455
Query: 239 AILTVGLDDKFGGAAVQHREAMGHESNHFLQYFTSALQYLDGGNPSGFNHVVTNPGAEKR 418
AILT LD++ GG VQ R G E H + F + G S T P A R
Sbjct: 456 AILTAQLDEELGGTPVQSRVVQGKEPAHLMSLFGGKPMIIYKGGTSR-EGGQTAP-ASTR 513
Query: 419 MFQVKGKRNVRVRQVD--PLISSMNKGDCFILDINNDIYVYVGERTKNVEKLKAISMANQ 592
+FQV+ R V+ P ++N D F+L + Y++VG EK A +
Sbjct: 514 LFQVRANSAGATRAVEVLPKAGALNSNDAFVLKTPSAAYLWVGTGASEAEKTGAQELLRV 573
Query: 593 IRDQ 604
+R Q
Sbjct: 574 LRAQ 577
Score = 37.9 bits (84), Expect = 0.031
Identities = 42/163 (25%), Positives = 66/163 (40%), Gaps = 8/163 (4%)
Frame = +2
Query: 173 NLSWDIHYWIGSETSQDEAGAAAILTVGL-DDKFGGAAVQHREAMGHESNHFLQYFTSAL 349
+L +IH W GS +++ E A ++ G+ D++ G A H G E LQ
Sbjct: 168 DLGNNIHQWCGSNSNRYERLKATQVSKGIRDNERSGRARVHVSEEGTEPEAMLQVL-GPK 226
Query: 350 QYLDGGNPSGFNHVVTNPGAEKRMFQVKGKRNVRVRQV---DPLISSMNKG-DCFILDIN 517
L G N K G + V V +P K DCFILD
Sbjct: 227 PALPAGTEDTAKEDAANRKLAKLYKVSNGAGTMSVSLVADENPFAQGALKSEDCFILDHG 286
Query: 518 ND--IYVYVGERTKNVEKLKAISMANQ-IRDQDHNGRGRVEII 637
D I+V+ G++ E+ A+ A+ I D+ + +V ++
Sbjct: 287 KDGKIFVWKGKQANTEERKAALKTASDFITKMDYPKQTQVSVL 329
>AL513122-5|CAI14415.1| 260|Homo sapiens gelsolin (amyloidosis,
Finnish type) protein.
Length = 260
Score = 223 bits (545), Expect = 4e-58
Identities = 102/205 (49%), Positives = 136/205 (66%)
Frame = +2
Query: 20 HPAFANAGRQAGVEIWRIQNFEPVAVQSKDFGKFYKGDSYIILKTTSDKRNNLSWDIHYW 199
HP F AG++ G++IWR++ F+ V V + +G F+ GD+Y+ILKT + NL +D+HYW
Sbjct: 5 HPEFLKAGKEPGLQIWRVEKFDLVPVPTNLYGDFFTGDAYVILKTVQLRNGNLQYDLHYW 64
Query: 200 IGSETSQDEAGAAAILTVGLDDKFGGAAVQHREAMGHESNHFLQYFTSALQYLDGGNPSG 379
+G+E SQDE+GAAAI TV LDD G AVQHRE G ES FL YF S L+Y GG SG
Sbjct: 65 LGNECSQDESGAAAIFTVQLDDYLNGRAVQHREVQGFESATFLGYFKSGLKYKKGGVASG 124
Query: 380 FNHVVTNPGAEKRMFQVKGKRNVRVRQVDPLISSMNKGDCFILDINNDIYVYVGERTKNV 559
F HVV N +R+FQVKG+R VR +V S N GDCFILD+ N+I+ + G +
Sbjct: 125 FKHVVPNEVVVQRLFQVKGRRVVRATEVPVSWESFNNGDCFILDLGNNIHQWCGSNSNRY 184
Query: 560 EKLKAISMANQIRDQDHNGRGRVEI 634
E+LKA ++ IRD + +GR RV +
Sbjct: 185 ERLKATQVSKGIRDNERSGRARVHV 209
>AL513122-4|CAI14414.1| 228|Homo sapiens gelsolin (amyloidosis,
Finnish type) protein.
Length = 228
Score = 223 bits (545), Expect = 4e-58
Identities = 102/205 (49%), Positives = 136/205 (66%)
Frame = +2
Query: 20 HPAFANAGRQAGVEIWRIQNFEPVAVQSKDFGKFYKGDSYIILKTTSDKRNNLSWDIHYW 199
HP F AG++ G++IWR++ F+ V V + +G F+ GD+Y+ILKT + NL +D+HYW
Sbjct: 16 HPEFLKAGKEPGLQIWRVEKFDLVPVPTNLYGDFFTGDAYVILKTVQLRNGNLQYDLHYW 75
Query: 200 IGSETSQDEAGAAAILTVGLDDKFGGAAVQHREAMGHESNHFLQYFTSALQYLDGGNPSG 379
+G+E SQDE+GAAAI TV LDD G AVQHRE G ES FL YF S L+Y GG SG
Sbjct: 76 LGNECSQDESGAAAIFTVQLDDYLNGRAVQHREVQGFESATFLGYFKSGLKYKKGGVASG 135
Query: 380 FNHVVTNPGAEKRMFQVKGKRNVRVRQVDPLISSMNKGDCFILDINNDIYVYVGERTKNV 559
F HVV N +R+FQVKG+R VR +V S N GDCFILD+ N+I+ + G +
Sbjct: 136 FKHVVPNEVVVQRLFQVKGRRVVRATEVPVSWESFNNGDCFILDLGNNIHQWCGSNSNRY 195
Query: 560 EKLKAISMANQIRDQDHNGRGRVEI 634
E+LKA ++ IRD + +GR RV +
Sbjct: 196 ERLKATQVSKGIRDNERSGRARVHV 220
>AL513122-3|CAI14413.1| 782|Homo sapiens gelsolin (amyloidosis,
Finnish type) protein.
Length = 782
Score = 223 bits (545), Expect = 4e-58
Identities = 102/205 (49%), Positives = 136/205 (66%)
Frame = +2
Query: 20 HPAFANAGRQAGVEIWRIQNFEPVAVQSKDFGKFYKGDSYIILKTTSDKRNNLSWDIHYW 199
HP F AG++ G++IWR++ F+ V V + +G F+ GD+Y+ILKT + NL +D+HYW
Sbjct: 56 HPEFLKAGKEPGLQIWRVEKFDLVPVPTNLYGDFFTGDAYVILKTVQLRNGNLQYDLHYW 115
Query: 200 IGSETSQDEAGAAAILTVGLDDKFGGAAVQHREAMGHESNHFLQYFTSALQYLDGGNPSG 379
+G+E SQDE+GAAAI TV LDD G AVQHRE G ES FL YF S L+Y GG SG
Sbjct: 116 LGNECSQDESGAAAIFTVQLDDYLNGRAVQHREVQGFESATFLGYFKSGLKYKKGGVASG 175
Query: 380 FNHVVTNPGAEKRMFQVKGKRNVRVRQVDPLISSMNKGDCFILDINNDIYVYVGERTKNV 559
F HVV N +R+FQVKG+R VR +V S N GDCFILD+ N+I+ + G +
Sbjct: 176 FKHVVPNEVVVQRLFQVKGRRVVRATEVPVSWESFNNGDCFILDLGNNIHQWCGSNSNRY 235
Query: 560 EKLKAISMANQIRDQDHNGRGRVEI 634
E+LKA ++ IRD + +GR RV +
Sbjct: 236 ERLKATQVSKGIRDNERSGRARVHV 260
Score = 96.7 bits (230), Expect = 6e-20
Identities = 62/184 (33%), Positives = 87/184 (47%), Gaps = 2/184 (1%)
Frame = +2
Query: 59 EIWRIQNFEPVAVQSKDFGKFYKGDSYIILKTTSDKRNNLSWDIHYWIGSETSQDEAGAA 238
+IWRI+ V V +G+FY GDSYIIL I+ W G++++QDE A+
Sbjct: 448 QIWRIEGSNKVPVDPATYGQFYGGDSYIILYNYRHGGRQ-GQIIYNWQGAQSTQDEVAAS 506
Query: 239 AILTVGLDDKFGGAAVQHREAMGHESNHFLQYFTSALQYLDGGNPSGFNHVVTNPGAEKR 418
AILT LD++ GG VQ R G E H + F + G S T P A R
Sbjct: 507 AILTAQLDEELGGTPVQSRVVQGKEPAHLMSLFGGKPMIIYKGGTSR-EGGQTAP-ASTR 564
Query: 419 MFQVKGKRNVRVRQVD--PLISSMNKGDCFILDINNDIYVYVGERTKNVEKLKAISMANQ 592
+FQV+ R V+ P ++N D F+L + Y++VG EK A +
Sbjct: 565 LFQVRANSAGATRAVEVLPKAGALNSNDAFVLKTPSAAYLWVGTGASEAEKTGAQELLRV 624
Query: 593 IRDQ 604
+R Q
Sbjct: 625 LRAQ 628
Score = 37.9 bits (84), Expect = 0.031
Identities = 42/163 (25%), Positives = 66/163 (40%), Gaps = 8/163 (4%)
Frame = +2
Query: 173 NLSWDIHYWIGSETSQDEAGAAAILTVGL-DDKFGGAAVQHREAMGHESNHFLQYFTSAL 349
+L +IH W GS +++ E A ++ G+ D++ G A H G E LQ
Sbjct: 219 DLGNNIHQWCGSNSNRYERLKATQVSKGIRDNERSGRARVHVSEEGTEPEAMLQVL-GPK 277
Query: 350 QYLDGGNPSGFNHVVTNPGAEKRMFQVKGKRNVRVRQV---DPLISSMNKG-DCFILDIN 517
L G N K G + V V +P K DCFILD
Sbjct: 278 PALPAGTEDTAKEDAANRKLAKLYKVSNGAGTMSVSLVADENPFAQGALKSEDCFILDHG 337
Query: 518 ND--IYVYVGERTKNVEKLKAISMANQ-IRDQDHNGRGRVEII 637
D I+V+ G++ E+ A+ A+ I D+ + +V ++
Sbjct: 338 KDGKIFVWKGKQANTEERKAALKTASDFITKMDYPKQTQVSVL 380
>AF276507-1|AAK60494.1| 715|Homo sapiens scinderin protein.
Length = 715
Score = 198 bits (482), Expect = 2e-50
Identities = 93/207 (44%), Positives = 127/207 (61%)
Frame = +2
Query: 20 HPAFANAGRQAGVEIWRIQNFEPVAVQSKDFGKFYKGDSYIILKTTSDKRNNLSWDIHYW 199
H FA AG+QAG+++WRI+ E V V G FY GD+Y++L T R ++ +H+W
Sbjct: 7 HEEFARAGKQAGLQVWRIEKLELVPVPQSAHGDFYVGDAYLVLHTAKTSRG-FTYHLHFW 65
Query: 200 IGSETSQDEAGAAAILTVGLDDKFGGAAVQHREAMGHESNHFLQYFTSALQYLDGGNPSG 379
+G E SQDE+ AAAI TV +DD GG VQ+RE G+ESN F+ YF L+Y GG SG
Sbjct: 66 LGKECSQDESTAAAIFTVQMDDYLGGKPVQNRELQGYESNDFVSYFKGGLKYKAGGVASG 125
Query: 380 FNHVVTNPGAEKRMFQVKGKRNVRVRQVDPLISSMNKGDCFILDINNDIYVYVGERTKNV 559
NHV+TN KR+ VKG+R VR +V S NKGDCFI+D+ +IY + G
Sbjct: 126 LNHVLTNDLTAKRLLHVKGRRVVRATEVPLSWDSFNKGDCFIIDLGTEIYQWCGSSCNKY 185
Query: 560 EKLKAISMANQIRDQDHNGRGRVEIID 640
E+LKA +A IR + GR + +++
Sbjct: 186 ERLKANQVATGIRYNERKGRSELIVVE 212
Score = 89.8 bits (213), Expect = 7e-18
Identities = 64/188 (34%), Positives = 97/188 (51%), Gaps = 7/188 (3%)
Frame = +2
Query: 56 VEIWRIQNFEPVAVQSKDFGKFYKGDSYIILKTTSDKRNNLSWDIHYWIGSETSQDEAGA 235
VEIWR++N + V +G+FY GD YIIL T R + I+ W G+ ++DE
Sbjct: 398 VEIWRVENNGRIQVDQNSYGEFYGGDCYIILYTYP--RGQI---IYTWQGANATRDELTT 452
Query: 236 AAILTVGLDDKFGGAAVQHREAMGHESNHFLQYFTS--ALQYLDGGNPSGFNHVVTNPGA 409
+A LTV LD GG AVQ R + E H L F + Y +G + G P
Sbjct: 453 SAFLTVQLDRSLGGQAVQIRVSQDKEPVHLLSLFKDKPLIIYKNGTSKKGGQ----APAP 508
Query: 410 EKRMFQVKGKRNV----RVRQVDPLISSMNKGDCFILDIN-NDIYVYVGERTKNVEKLKA 574
R+FQV +RN+ R+ +VD +S+N D F+L ++ N Y++VG+ E+ A
Sbjct: 509 PTRLFQV--RRNLASITRIVEVDVDANSLNSNDVFVLKLSQNSGYIWVGKGASQEEEKGA 566
Query: 575 ISMANQIR 598
+A+ ++
Sbjct: 567 EYVASVLK 574
Score = 30.7 bits (66), Expect = 4.7
Identities = 12/44 (27%), Positives = 24/44 (54%)
Frame = +2
Query: 494 DCFILDINNDIYVYVGERTKNVEKLKAISMANQIRDQDHNGRGR 625
D +LD I++++G+ VEK +++ A + D +GR +
Sbjct: 644 DVMLLDAWEQIFIWIGKDANEVEKKESLKSAKMYLETDPSGRDK 687
>AC005281-1|AAD15423.1| 527|Homo sapiens WUGSC:H_DJ0722F20.1
protein.
Length = 527
Score = 198 bits (482), Expect = 2e-50
Identities = 93/207 (44%), Positives = 127/207 (61%)
Frame = +2
Query: 20 HPAFANAGRQAGVEIWRIQNFEPVAVQSKDFGKFYKGDSYIILKTTSDKRNNLSWDIHYW 199
H FA AG+QAG+++WRI+ E V V G FY GD+Y++L T R ++ +H+W
Sbjct: 7 HEEFARAGKQAGLQVWRIEKLELVPVPQSAHGDFYVGDAYLVLHTAKTSRG-FTYHLHFW 65
Query: 200 IGSETSQDEAGAAAILTVGLDDKFGGAAVQHREAMGHESNHFLQYFTSALQYLDGGNPSG 379
+G E SQDE+ AAAI TV +DD GG VQ+RE G+ESN F+ YF L+Y GG SG
Sbjct: 66 LGKECSQDESTAAAIFTVQMDDYLGGKPVQNRELQGYESNDFVSYFKGGLKYKAGGVASG 125
Query: 380 FNHVVTNPGAEKRMFQVKGKRNVRVRQVDPLISSMNKGDCFILDINNDIYVYVGERTKNV 559
NHV+TN KR+ VKG+R VR +V S NKGDCFI+D+ +IY + G
Sbjct: 126 LNHVLTNDLTAKRLLHVKGRRVVRATEVPLSWDSFNKGDCFIIDLGTEIYQWCGSSCNKY 185
Query: 560 EKLKAISMANQIRDQDHNGRGRVEIID 640
E+LKA +A IR + GR + +++
Sbjct: 186 ERLKANQVATGIRYNERKGRSELIVVE 212
Score = 74.9 bits (176), Expect = 2e-13
Identities = 48/128 (37%), Positives = 65/128 (50%), Gaps = 2/128 (1%)
Frame = +2
Query: 56 VEIWRIQNFEPVAVQSKDFGKFYKGDSYIILKTTSDKRNNLSWDIHYWIGSETSQDEAGA 235
VEIWR++N + V +G+FY GD YIIL T R + I+ W G+ ++DE
Sbjct: 398 VEIWRVENNGRIQVDQNSYGEFYGGDCYIILYTYP--RGQI---IYTWQGANATRDELTT 452
Query: 236 AAILTVGLDDKFGGAAVQHREAMGHESNHFLQYFTS--ALQYLDGGNPSGFNHVVTNPGA 409
+A LTV LD GG AVQ R + G E H L F + Y +G + G P
Sbjct: 453 SAFLTVQLDRSLGGQAVQIRVSQGKEPVHLLSLFKDKPLIIYKNGTSKKGGQ----APAP 508
Query: 410 EKRMFQVK 433
R+FQV+
Sbjct: 509 PTRLFQVR 516
>AB067492-1|BAB67798.1| 626|Homo sapiens KIAA1905 protein protein.
Length = 626
Score = 198 bits (482), Expect = 2e-50
Identities = 93/207 (44%), Positives = 127/207 (61%)
Frame = +2
Query: 20 HPAFANAGRQAGVEIWRIQNFEPVAVQSKDFGKFYKGDSYIILKTTSDKRNNLSWDIHYW 199
H FA AG+QAG+++WRI+ E V V G FY GD+Y++L T R ++ +H+W
Sbjct: 53 HEEFARAGKQAGLQVWRIEKLELVPVPQSAHGDFYVGDAYLVLHTAKTSRG-FTYHLHFW 111
Query: 200 IGSETSQDEAGAAAILTVGLDDKFGGAAVQHREAMGHESNHFLQYFTSALQYLDGGNPSG 379
+G E SQDE+ AAAI TV +DD GG VQ+RE G+ESN F+ YF L+Y GG SG
Sbjct: 112 LGKECSQDESTAAAIFTVQMDDYLGGKPVQNRELQGYESNDFVSYFKGGLKYKAGGVASG 171
Query: 380 FNHVVTNPGAEKRMFQVKGKRNVRVRQVDPLISSMNKGDCFILDINNDIYVYVGERTKNV 559
NHV+TN KR+ VKG+R VR +V S NKGDCFI+D+ +IY + G
Sbjct: 172 LNHVLTNDLTAKRLLHVKGRRVVRATEVPLSWDSFNKGDCFIIDLGTEIYQWCGSSCNKY 231
Query: 560 EKLKAISMANQIRDQDHNGRGRVEIID 640
E+LKA +A IR + GR + +++
Sbjct: 232 ERLKANQVATGIRYNERKGRSELIVVE 258
Score = 74.9 bits (176), Expect = 2e-13
Identities = 48/128 (37%), Positives = 65/128 (50%), Gaps = 2/128 (1%)
Frame = +2
Query: 56 VEIWRIQNFEPVAVQSKDFGKFYKGDSYIILKTTSDKRNNLSWDIHYWIGSETSQDEAGA 235
VEIWR++N + V +G+FY GD YIIL T R + I+ W G+ ++DE
Sbjct: 444 VEIWRVENNGRIQVDQNSYGEFYGGDCYIILYTYP--RGQI---IYTWQGANATRDELTT 498
Query: 236 AAILTVGLDDKFGGAAVQHREAMGHESNHFLQYFTS--ALQYLDGGNPSGFNHVVTNPGA 409
+A LTV LD GG AVQ R + G E H L F + Y +G + G P
Sbjct: 499 SAFLTVQLDRSLGGQAVQIRVSQGKEPVHLLSLFKDKPLIIYKNGTSKKGGQ----APAP 554
Query: 410 EKRMFQVK 433
R+FQV+
Sbjct: 555 PTRLFQVR 562
>BC021090-1|AAH21090.1| 715|Homo sapiens SCIN protein protein.
Length = 715
Score = 197 bits (481), Expect = 2e-50
Identities = 93/207 (44%), Positives = 127/207 (61%)
Frame = +2
Query: 20 HPAFANAGRQAGVEIWRIQNFEPVAVQSKDFGKFYKGDSYIILKTTSDKRNNLSWDIHYW 199
H FA AG+QAG+++WRI+ E V V G FY GD+Y++L T R ++ +H+W
Sbjct: 7 HEEFARAGKQAGLQVWRIEKLELVPVPQSAHGDFYVGDAYLVLHTAKTSRG-FTYRLHFW 65
Query: 200 IGSETSQDEAGAAAILTVGLDDKFGGAAVQHREAMGHESNHFLQYFTSALQYLDGGNPSG 379
+G E SQDE+ AAAI TV +DD GG VQ+RE G+ESN F+ YF L+Y GG SG
Sbjct: 66 LGKECSQDESTAAAIFTVQMDDYLGGKPVQNRELQGYESNDFVSYFKGGLKYKAGGVASG 125
Query: 380 FNHVVTNPGAEKRMFQVKGKRNVRVRQVDPLISSMNKGDCFILDINNDIYVYVGERTKNV 559
NHV+TN KR+ VKG+R VR +V S NKGDCFI+D+ +IY + G
Sbjct: 126 LNHVLTNDLTAKRLLHVKGRRVVRATEVPLSWDSFNKGDCFIIDLGTEIYQWCGSSCNKY 185
Query: 560 EKLKAISMANQIRDQDHNGRGRVEIID 640
E+LKA +A IR + GR + +++
Sbjct: 186 ERLKANQVATGIRYNERKGRSELIVVE 212
Score = 92.3 bits (219), Expect = 1e-18
Identities = 65/188 (34%), Positives = 97/188 (51%), Gaps = 7/188 (3%)
Frame = +2
Query: 56 VEIWRIQNFEPVAVQSKDFGKFYKGDSYIILKTTSDKRNNLSWDIHYWIGSETSQDEAGA 235
VEIWR++N + V +G+FY GD YIIL T R + I+ W G+ ++DE
Sbjct: 398 VEIWRVENNGRIQVDQNSYGEFYGGDCYIILYTYP--RGQI---IYTWQGANATRDELTT 452
Query: 236 AAILTVGLDDKFGGAAVQHREAMGHESNHFLQYFTS--ALQYLDGGNPSGFNHVVTNPGA 409
+A LTV LD GG AVQ R + G E H L F + Y +G + G P
Sbjct: 453 SAFLTVQLDRSLGGQAVQIRVSQGKEPVHLLSLFKDKPLIIYKNGTSKKGGQ----APAP 508
Query: 410 EKRMFQVKGKRNV----RVRQVDPLISSMNKGDCFILDI-NNDIYVYVGERTKNVEKLKA 574
R+FQV +RN+ R+ +VD +S+N D F+L + N Y++VG+ E+ A
Sbjct: 509 PTRLFQV--RRNLASITRIVEVDVDANSLNSNDVFVLKLPQNSGYIWVGKGASQEEEKGA 566
Query: 575 ISMANQIR 598
+A+ ++
Sbjct: 567 EYVASVLK 574
Score = 30.7 bits (66), Expect = 4.7
Identities = 12/44 (27%), Positives = 24/44 (54%)
Frame = +2
Query: 494 DCFILDINNDIYVYVGERTKNVEKLKAISMANQIRDQDHNGRGR 625
D +LD I++++G+ VEK +++ A + D +GR +
Sbjct: 644 DVMLLDAWEQIFIWIGKDANEVEKKESLKSAKMYLETDPSGRDK 687
>AK075123-1|BAC11416.1| 715|Homo sapiens protein ( Homo sapiens
cDNA FLJ90642 fis, clone PLACE1004078, highly similar to
Bovine mRNA for adseverin. ).
Length = 715
Score = 197 bits (480), Expect = 3e-50
Identities = 93/207 (44%), Positives = 127/207 (61%)
Frame = +2
Query: 20 HPAFANAGRQAGVEIWRIQNFEPVAVQSKDFGKFYKGDSYIILKTTSDKRNNLSWDIHYW 199
H FA AG+QAG+++WRI+ E V V G FY GD+Y++L T R ++ +H+W
Sbjct: 7 HEEFARAGKQAGLQVWRIEKLELVPVPQSAHGDFYVGDAYLMLHTAKTSRG-FTYHLHFW 65
Query: 200 IGSETSQDEAGAAAILTVGLDDKFGGAAVQHREAMGHESNHFLQYFTSALQYLDGGNPSG 379
+G E SQDE+ AAAI TV +DD GG VQ+RE G+ESN F+ YF L+Y GG SG
Sbjct: 66 LGKECSQDESTAAAIFTVQMDDYLGGKPVQNRELQGYESNDFVSYFKGGLKYKAGGVASG 125
Query: 380 FNHVVTNPGAEKRMFQVKGKRNVRVRQVDPLISSMNKGDCFILDINNDIYVYVGERTKNV 559
NHV+TN KR+ VKG+R VR +V S NKGDCFI+D+ +IY + G
Sbjct: 126 LNHVLTNDLTAKRLLHVKGRRVVRATEVPLSWDSFNKGDCFIIDLGTEIYQWCGSSCNKY 185
Query: 560 EKLKAISMANQIRDQDHNGRGRVEIID 640
E+LKA +A IR + GR + +++
Sbjct: 186 ERLKANQVATGIRYNERKGRSELIVVE 212
Score = 92.3 bits (219), Expect = 1e-18
Identities = 65/188 (34%), Positives = 97/188 (51%), Gaps = 7/188 (3%)
Frame = +2
Query: 56 VEIWRIQNFEPVAVQSKDFGKFYKGDSYIILKTTSDKRNNLSWDIHYWIGSETSQDEAGA 235
VEIWR++N + V +G+FY GD YIIL T R + I+ W G+ ++DE
Sbjct: 398 VEIWRVENNGRIQVDQNSYGEFYGGDCYIILYTYP--RGQI---IYTWQGANATRDELTT 452
Query: 236 AAILTVGLDDKFGGAAVQHREAMGHESNHFLQYFTS--ALQYLDGGNPSGFNHVVTNPGA 409
+A LTV LD GG AVQ R + G E H L F + Y +G + G P
Sbjct: 453 SAFLTVQLDRSLGGQAVQIRVSQGKEPVHLLSLFKDKPLIIYKNGTSKKGGQ----APAP 508
Query: 410 EKRMFQVKGKRNV----RVRQVDPLISSMNKGDCFILDI-NNDIYVYVGERTKNVEKLKA 574
R+FQV +RN+ R+ +VD +S+N D F+L + N Y++VG+ E+ A
Sbjct: 509 PTRLFQV--RRNLASITRIVEVDVDANSLNSNDVFVLKLPQNSGYIWVGKGASQEEEKGA 566
Query: 575 ISMANQIR 598
+A+ ++
Sbjct: 567 EYVASVLK 574
Score = 30.7 bits (66), Expect = 4.7
Identities = 12/44 (27%), Positives = 24/44 (54%)
Frame = +2
Query: 494 DCFILDINNDIYVYVGERTKNVEKLKAISMANQIRDQDHNGRGR 625
D +LD I++++G+ VEK +++ A + D +GR +
Sbjct: 644 DVMLLDAWEQIFIWIGKDANEVEKKESLKSAKMYLETDPSGRDK 687
>AF041449-1|AAC25051.1| 819|Homo sapiens advillin protein.
Length = 819
Score = 176 bits (429), Expect = 5e-44
Identities = 88/205 (42%), Positives = 118/205 (57%)
Frame = +2
Query: 26 AFANAGRQAGVEIWRIQNFEPVAVQSKDFGKFYKGDSYIILKTTSDKRNNLSWDIHYWIG 205
AF G+ +WRI+ E V G FY+GD Y+IL T + LS DIH+WIG
Sbjct: 6 AFRAVDNDPGIIVWRIEKMELALVPVSAHGNFYEGDCYVILSTRR-VASLLSQDIHFWIG 64
Query: 206 SETSQDEAGAAAILTVGLDDKFGGAAVQHREAMGHESNHFLQYFTSALQYLDGGNPSGFN 385
++SQDE AAI T LDD GG+ VQHRE HES+ F YF + Y GG SG
Sbjct: 65 KDSSQDEQSCAAIYTTQLDDYLGGSPVQHREVQYHESDTFRGYFKQGIIYKQGGVASGMK 124
Query: 386 HVVTNPGAEKRMFQVKGKRNVRVRQVDPLISSMNKGDCFILDINNDIYVYVGERTKNVEK 565
HV TN KR+ VKGKRN+R +V+ S N+GD F+LD+ I + G + + E+
Sbjct: 125 HVETNTYDVKRLLHVKGKRNIRATEVEMSWDSFNRGDVFLLDLGKVIIQWNGPESNSGER 184
Query: 566 LKAISMANQIRDQDHNGRGRVEIID 640
LKA+ +A IRD++ GR + +I+
Sbjct: 185 LKAMLLAKDIRDRERGGRAEIGVIE 209
Score = 107 bits (257), Expect = 3e-23
Identities = 65/190 (34%), Positives = 98/190 (51%), Gaps = 4/190 (2%)
Frame = +2
Query: 56 VEIWRIQNFEPVAVQSKDFGKFYKGDSYIILKT--TSDKRNNLSWDIHYWIGSETSQDEA 229
VE+WRI+N E V V+ + +G FY GD Y++L T + K +++ ++ W SQDE
Sbjct: 397 VEVWRIENLELVPVEYQWYGFFYGGDCYLVLYTYEVNGKPHHI---LYIWQDRHASQDEL 453
Query: 230 GAAAILTVGLDDKFGGAAVQHREAMGHESNHFLQYFTSALQYLDGGNPSGFNHVVTNPGA 409
A+A V +D +F GAAVQ R MG E HF+ F L +GG N P
Sbjct: 454 AASAYQAVEVDRQFDGAAVQVRVRMGTEPRHFMAIFKGKLVIFEGGTSRKGN---AEPDP 510
Query: 410 EKRMFQVKG--KRNVRVRQVDPLISSMNKGDCFILDINNDIYVYVGERTKNVEKLKAISM 583
R+FQ+ G K N + +V SS+N D F+L + Y++ G+ + E+ A +
Sbjct: 511 PVRLFQIHGNDKSNTKAVEVPAFASSLNSNDVFLLRTQAEHYLWYGKGSSGDERAMAKEL 570
Query: 584 ANQIRDQDHN 613
A+ + D N
Sbjct: 571 ASLLCDGSEN 580
Score = 31.1 bits (67), Expect = 3.6
Identities = 34/146 (23%), Positives = 53/146 (36%), Gaps = 3/146 (2%)
Frame = +2
Query: 191 HY-WIGSETSQDEAGAAAILTVGLDDKFGGAAVQHREAMGHESNHFLQYFTSALQYLDGG 367
HY W G +S DE A L L D ++ A G E F Y
Sbjct: 551 HYLWYGKGSSGDERAMAKELASLLCD-----GSENTVAEGQEPAEFWDLLGGKTPY---A 602
Query: 368 NPSGFNHVVTNPGAEKRMFQVKGKRN--VRVRQVDPLISSMNKGDCFILDINNDIYVYVG 541
N + + + R+F+ K V D +N D +LD + +++++G
Sbjct: 603 NDKRLQQEILD--VQSRLFECSNKTGQFVVTEITDFTQDDLNPTDVMLLDTWDQVFLWIG 660
Query: 542 ERTKNVEKLKAISMANQIRDQDHNGR 619
EK A++ A Q +GR
Sbjct: 661 AEANATEKESALATAQQYLHTHPSGR 686
>X12901-1|CAA31386.1| 827|Homo sapiens protein ( Human mRNA for
villin. ).
Length = 827
Score = 175 bits (425), Expect = 1e-43
Identities = 88/196 (44%), Positives = 119/196 (60%)
Frame = +2
Query: 53 GVEIWRIQNFEPVAVQSKDFGKFYKGDSYIILKTTSDKRNNLSWDIHYWIGSETSQDEAG 232
G++IWRI+ + V V S FG F+ GD YIIL ++LS+DIHYWIG ++S DE G
Sbjct: 18 GLQIWRIEAMQMVPVPSSTFGSFFDGDCYIIL-AIHKTASSLSYDIHYWIGQDSSLDEQG 76
Query: 233 AAAILTVGLDDKFGGAAVQHREAMGHESNHFLQYFTSALQYLDGGNPSGFNHVVTNPGAE 412
AAAI T +DD G AVQHRE G+ES F YF L GG SG HV TN
Sbjct: 77 AAAIYTTQMDDFLKGRAVQHREVQGNESEAFRGYFKQGLVIRKGGVASGMKHVETNSYDV 136
Query: 413 KRMFQVKGKRNVRVRQVDPLISSMNKGDCFILDINNDIYVYVGERTKNVEKLKAISMANQ 592
+R+ VKGKRNV +V+ S N+GD F+LD+ I + G + +E+L+ +++A +
Sbjct: 137 QRLLHVKGKRNVVAGEVEMSWKSFNRGDVFLLDLGKLIIQWNGPESTRMERLRGMTLAKE 196
Query: 593 IRDQDHNGRGRVEIID 640
IRDQ+ GR V ++D
Sbjct: 197 IRDQERGGRTYVGVVD 212
Score = 103 bits (246), Expect = 7e-22
Identities = 65/184 (35%), Positives = 96/184 (52%), Gaps = 4/184 (2%)
Frame = +2
Query: 56 VEIWRIQNFEPVAVQSKDFGKFYKGDSYIILKT--TSDKRNNLSWDIHYWIGSETSQDEA 229
V++WRI+N E V V SK G FY GD Y++L T +K++ L ++ W GS+ SQDE
Sbjct: 400 VQVWRIENLELVPVDSKWLGHFYGGDCYLLLYTYLIGEKQHYL---LYVWQGSQASQDEI 456
Query: 230 GAAAILTVGLDDKFGGAAVQHREAMGHESNHFLQYFTSALQYLDGGNPSGFNHVVTNPGA 409
A+A V LD K+ G VQ R MG E H + F + GG S N++ T P
Sbjct: 457 TASAYQAVILDQKYNGEPVQIRVPMGKEPPHLMSIFKGRMVVYQGGT-SRTNNLETGPST 515
Query: 410 EKRMFQVK--GKRNVRVRQVDPLISSMNKGDCFILDINNDIYVYVGERTKNVEKLKAISM 583
R+FQV+ G N + +V + +N D F+L + Y++ G+ E+ A +
Sbjct: 516 --RLFQVQGTGANNTKAFEVPARANFLNSNDVFVLKTQSCCYLWCGKGCSGDEREMAKMV 573
Query: 584 ANQI 595
A+ I
Sbjct: 574 ADTI 577
>BC017303-1|AAH17303.1| 421|Homo sapiens VIL1 protein protein.
Length = 421
Score = 175 bits (425), Expect = 1e-43
Identities = 88/196 (44%), Positives = 119/196 (60%)
Frame = +2
Query: 53 GVEIWRIQNFEPVAVQSKDFGKFYKGDSYIILKTTSDKRNNLSWDIHYWIGSETSQDEAG 232
G++IWRI+ + V V S FG F+ GD YIIL ++LS+DIHYWIG ++S DE G
Sbjct: 18 GLQIWRIEAMQMVPVPSSTFGSFFDGDCYIIL-AIHKTASSLSYDIHYWIGQDSSLDEQG 76
Query: 233 AAAILTVGLDDKFGGAAVQHREAMGHESNHFLQYFTSALQYLDGGNPSGFNHVVTNPGAE 412
AAAI T +DD G AVQHRE G+ES F YF L GG SG HV TN
Sbjct: 77 AAAIYTTQMDDFLKGRAVQHREVQGNESEAFRGYFKQGLVIRKGGVASGMKHVETNSYDV 136
Query: 413 KRMFQVKGKRNVRVRQVDPLISSMNKGDCFILDINNDIYVYVGERTKNVEKLKAISMANQ 592
+R+ VKGKRNV +V+ S N+GD F+LD+ I + G + +E+L+ +++A +
Sbjct: 137 QRLLHVKGKRNVVAGEVEMSWKSFNRGDVFLLDLGKLIIQWNGPESTRMERLRGMTLAKE 196
Query: 593 IRDQDHNGRGRVEIID 640
IRDQ+ GR V ++D
Sbjct: 197 IRDQERGGRTYVGVVD 212
>AK223398-1|BAD97118.1| 827|Homo sapiens villin 1 variant protein.
Length = 827
Score = 175 bits (425), Expect = 1e-43
Identities = 88/196 (44%), Positives = 119/196 (60%)
Frame = +2
Query: 53 GVEIWRIQNFEPVAVQSKDFGKFYKGDSYIILKTTSDKRNNLSWDIHYWIGSETSQDEAG 232
G++IWRI+ + V V S FG F+ GD YIIL ++LS+DIHYWIG ++S DE G
Sbjct: 18 GLQIWRIEAMQMVPVPSSTFGSFFDGDCYIIL-AIHKTASSLSYDIHYWIGQDSSLDEQG 76
Query: 233 AAAILTVGLDDKFGGAAVQHREAMGHESNHFLQYFTSALQYLDGGNPSGFNHVVTNPGAE 412
AAAI T +DD G AVQHRE G+ES F YF L GG SG HV TN
Sbjct: 77 AAAIYTTQMDDFLKGRAVQHREVQGNESEAFRGYFKQGLVIRKGGVASGMKHVETNSYDV 136
Query: 413 KRMFQVKGKRNVRVRQVDPLISSMNKGDCFILDINNDIYVYVGERTKNVEKLKAISMANQ 592
+R+ VKGKRNV +V+ S N+GD F+LD+ I + G + +E+L+ +++A +
Sbjct: 137 QRLLHVKGKRNVVAGEVEMSWKSFNRGDVFLLDLGKLIIQWNGPESTRMERLRGMTLAKE 196
Query: 593 IRDQDHNGRGRVEIID 640
IRDQ+ GR V ++D
Sbjct: 197 IRDQERGGRTYVGVVD 212
Score = 103 bits (246), Expect = 7e-22
Identities = 65/184 (35%), Positives = 96/184 (52%), Gaps = 4/184 (2%)
Frame = +2
Query: 56 VEIWRIQNFEPVAVQSKDFGKFYKGDSYIILKT--TSDKRNNLSWDIHYWIGSETSQDEA 229
V++WRI+N E V V SK G FY GD Y++L T +K++ L ++ W GS+ SQDE
Sbjct: 400 VQVWRIENLELVPVDSKWLGHFYGGDCYLLLYTYLIGEKQHYL---LYVWQGSQASQDEI 456
Query: 230 GAAAILTVGLDDKFGGAAVQHREAMGHESNHFLQYFTSALQYLDGGNPSGFNHVVTNPGA 409
A+A V LD K+ G VQ R MG E H + F + GG S N++ T P
Sbjct: 457 TASAYQAVILDQKYNGEPVQIRVPMGKEPPHLMSIFKGRMVVYQGGT-SRTNNLETGPST 515
Query: 410 EKRMFQVK--GKRNVRVRQVDPLISSMNKGDCFILDINNDIYVYVGERTKNVEKLKAISM 583
R+FQV+ G N + +V + +N D F+L + Y++ G+ E+ A +
Sbjct: 516 --RLFQVQGTGANNTKAFEVPARANFLNSNDVFVLKTQSCCYLWCGKGCSGDEREMAKMV 573
Query: 584 ANQI 595
A+ I
Sbjct: 574 ADTI 577
>BC111730-1|AAI11731.1| 812|Homo sapiens AVIL protein protein.
Length = 812
Score = 166 bits (404), Expect = 5e-41
Identities = 85/203 (41%), Positives = 116/203 (57%)
Frame = +2
Query: 32 ANAGRQAGVEIWRIQNFEPVAVQSKDFGKFYKGDSYIILKTTSDKRNNLSWDIHYWIGSE 211
++ G +IW + E V G FY+GD Y+IL T + LS DIH+WIG +
Sbjct: 2 SSTGHPGSYKIWG-EKMELALVPVSAHGNFYEGDCYVILSTRR-VASLLSQDIHFWIGKD 59
Query: 212 TSQDEAGAAAILTVGLDDKFGGAAVQHREAMGHESNHFLQYFTSALQYLDGGNPSGFNHV 391
+SQDE AAI T LDD GG+ VQHRE HES+ F YF + Y GG SG HV
Sbjct: 60 SSQDEQSCAAIYTTQLDDYLGGSPVQHREVQYHESDTFRGYFKQGIIYKQGGVASGMKHV 119
Query: 392 VTNPGAEKRMFQVKGKRNVRVRQVDPLISSMNKGDCFILDINNDIYVYVGERTKNVEKLK 571
TN KR+ VKGKRN+R +V+ S N+GD F+LD+ I + G + + E+LK
Sbjct: 120 ETNTYDVKRLLHVKGKRNIRATEVEMSWDSFNRGDVFLLDLGKVIIQWNGPESNSGERLK 179
Query: 572 AISMANQIRDQDHNGRGRVEIID 640
A+ +A IRD++ GR + +I+
Sbjct: 180 AMLLAKDIRDRERGGRAEIGVIE 202
Score = 110 bits (264), Expect = 5e-24
Identities = 66/190 (34%), Positives = 99/190 (52%), Gaps = 4/190 (2%)
Frame = +2
Query: 56 VEIWRIQNFEPVAVQSKDFGKFYKGDSYIILKT--TSDKRNNLSWDIHYWIGSETSQDEA 229
VE+WRI+N E V V+ + +G FY GD Y++L T + K +++ ++ W G SQDE
Sbjct: 390 VEVWRIENLELVPVEYQWYGFFYGGDCYLVLYTYEVNGKPHHI---LYIWQGRHASQDEL 446
Query: 230 GAAAILTVGLDDKFGGAAVQHREAMGHESNHFLQYFTSALQYLDGGNPSGFNHVVTNPGA 409
A+A V +D +F GAAVQ R MG E HF+ F L +GG N P
Sbjct: 447 AASAYQAVEVDRQFDGAAVQVRVRMGTEPRHFMAIFKGKLVIFEGGTSRKGN---AEPDP 503
Query: 410 EKRMFQVKG--KRNVRVRQVDPLISSMNKGDCFILDINNDIYVYVGERTKNVEKLKAISM 583
R+FQ+ G K N + +V SS+N D F+L + Y++ G+ + E+ A +
Sbjct: 504 PVRLFQIHGNDKSNTKAVEVPAFASSLNSNDVFLLRTQAEHYLWYGKGSSGDERAMAKEL 563
Query: 584 ANQIRDQDHN 613
A+ + D N
Sbjct: 564 ASLLCDGSEN 573
Score = 31.1 bits (67), Expect = 3.6
Identities = 34/146 (23%), Positives = 53/146 (36%), Gaps = 3/146 (2%)
Frame = +2
Query: 191 HY-WIGSETSQDEAGAAAILTVGLDDKFGGAAVQHREAMGHESNHFLQYFTSALQYLDGG 367
HY W G +S DE A L L D ++ A G E F Y
Sbjct: 544 HYLWYGKGSSGDERAMAKELASLLCD-----GSENTVAEGQEPAEFWDLLGGKTPY---A 595
Query: 368 NPSGFNHVVTNPGAEKRMFQVKGKRN--VRVRQVDPLISSMNKGDCFILDINNDIYVYVG 541
N + + + R+F+ K V D +N D +LD + +++++G
Sbjct: 596 NDKRLQQEILD--VQSRLFECSNKTGQFVVTEITDFTQDDLNPTDVMLLDTWDQVFLWIG 653
Query: 542 ERTKNVEKLKAISMANQIRDQDHNGR 619
EK A++ A Q +GR
Sbjct: 654 AEANATEKESALATAQQYLHTHPSGR 679
>M94345-1|AAA59570.1| 348|Homo sapiens macrophage capping protein
protein.
Length = 348
Score = 165 bits (400), Expect = 2e-40
Identities = 79/204 (38%), Positives = 125/204 (61%), Gaps = 1/204 (0%)
Frame = +2
Query: 29 FANAGRQAGVEIWRIQNFEPVAVQSKDFGKFYKGDSYIILKTTSDKRNNLSWDIHYWIGS 208
F + + G+ +WR++ +PV V ++ G F+ GDSY++L ++ ++L H WIG
Sbjct: 12 FPGSVQDPGLHVWRVEKLKPVPVAQENQGVFFSGDSYLVLHNGPEEVSHL----HLWIGQ 67
Query: 209 ETSQDEAGAAAILTVGLDDKFGGAAVQHREAMGHESNHFLQYFTSALQYLDGGNPSGFNH 388
++S+DE GA A+L V L+ G VQHRE G+ES+ F+ YF L+Y +GG S F+
Sbjct: 68 QSSRDEQGACAVLAVHLNTLLGERPVQHREVQGNESDLFMSYFPRGLKYQEGGVESAFHK 127
Query: 389 VVTN-PGAEKRMFQVKGKRNVRVRQVDPLISSMNKGDCFILDINNDIYVYVGERTKNVEK 565
T P A K+++QVKGK+N+R + S N GDCFILD+ +I+ + G ++ +E+
Sbjct: 128 TSTGAPAAIKKLYQVKGKKNIRATERALNWDSFNTGDCFILDLGQNIFAWCGGKSNILER 187
Query: 566 LKAISMANQIRDQDHNGRGRVEII 637
KA +A IRD + G+ +VEI+
Sbjct: 188 NKARDLALAIRDSERQGKAQVEIV 211
>BC014549-1|AAH14549.1| 348|Homo sapiens capping protein (actin
filament), gelsolin-like protein.
Length = 348
Score = 165 bits (400), Expect = 2e-40
Identities = 79/204 (38%), Positives = 125/204 (61%), Gaps = 1/204 (0%)
Frame = +2
Query: 29 FANAGRQAGVEIWRIQNFEPVAVQSKDFGKFYKGDSYIILKTTSDKRNNLSWDIHYWIGS 208
F + + G+ +WR++ +PV V ++ G F+ GDSY++L ++ ++L H WIG
Sbjct: 12 FPGSVQDPGLHVWRVEKLKPVPVAQENQGVFFSGDSYLVLHNGPEEVSHL----HLWIGQ 67
Query: 209 ETSQDEAGAAAILTVGLDDKFGGAAVQHREAMGHESNHFLQYFTSALQYLDGGNPSGFNH 388
++S+DE GA A+L V L+ G VQHRE G+ES+ F+ YF L+Y +GG S F+
Sbjct: 68 QSSRDEQGACAVLAVHLNTLLGERPVQHREVQGNESDLFMSYFPRGLKYQEGGVESAFHK 127
Query: 389 VVTN-PGAEKRMFQVKGKRNVRVRQVDPLISSMNKGDCFILDINNDIYVYVGERTKNVEK 565
T P A K+++QVKGK+N+R + S N GDCFILD+ +I+ + G ++ +E+
Sbjct: 128 TSTGAPAAIKKLYQVKGKKNIRATERALNWDSFNTGDCFILDLGQNIFAWCGGKSNILER 187
Query: 566 LKAISMANQIRDQDHNGRGRVEII 637
KA +A IRD + G+ +VEI+
Sbjct: 188 NKARDLALAIRDSERQGKAQVEIV 211
>BC000728-1|AAH00728.1| 348|Homo sapiens capping protein (actin
filament), gelsolin-like protein.
Length = 348
Score = 165 bits (400), Expect = 2e-40
Identities = 79/204 (38%), Positives = 125/204 (61%), Gaps = 1/204 (0%)
Frame = +2
Query: 29 FANAGRQAGVEIWRIQNFEPVAVQSKDFGKFYKGDSYIILKTTSDKRNNLSWDIHYWIGS 208
F + + G+ +WR++ +PV V ++ G F+ GDSY++L ++ ++L H WIG
Sbjct: 12 FPGSVQDPGLHVWRVEKLKPVPVAQENQGVFFSGDSYLVLHNGPEEVSHL----HLWIGQ 67
Query: 209 ETSQDEAGAAAILTVGLDDKFGGAAVQHREAMGHESNHFLQYFTSALQYLDGGNPSGFNH 388
++S+DE GA A+L V L+ G VQHRE G+ES+ F+ YF L+Y +GG S F+
Sbjct: 68 QSSRDEQGACAVLAVHLNTLLGERPVQHREVQGNESDLFMSYFPRGLKYQEGGVESAFHK 127
Query: 389 VVTN-PGAEKRMFQVKGKRNVRVRQVDPLISSMNKGDCFILDINNDIYVYVGERTKNVEK 565
T P A K+++QVKGK+N+R + S N GDCFILD+ +I+ + G ++ +E+
Sbjct: 128 TSTGAPAAIKKLYQVKGKKNIRATERALNWDSFNTGDCFILDLGQNIFAWCGGKSNILER 187
Query: 566 LKAISMANQIRDQDHNGRGRVEII 637
KA +A IRD + G+ +VEI+
Sbjct: 188 NKARDLALAIRDSERQGKAQVEIV 211
>AC062037-3|AAY24128.1| 348|Homo sapiens unknown protein.
Length = 348
Score = 165 bits (400), Expect = 2e-40
Identities = 79/204 (38%), Positives = 125/204 (61%), Gaps = 1/204 (0%)
Frame = +2
Query: 29 FANAGRQAGVEIWRIQNFEPVAVQSKDFGKFYKGDSYIILKTTSDKRNNLSWDIHYWIGS 208
F + + G+ +WR++ +PV V ++ G F+ GDSY++L ++ ++L H WIG
Sbjct: 12 FPGSVQDPGLHVWRVEKLKPVPVAQENQGVFFSGDSYLVLHNGPEEVSHL----HLWIGQ 67
Query: 209 ETSQDEAGAAAILTVGLDDKFGGAAVQHREAMGHESNHFLQYFTSALQYLDGGNPSGFNH 388
++S+DE GA A+L V L+ G VQHRE G+ES+ F+ YF L+Y +GG S F+
Sbjct: 68 QSSRDEQGACAVLAVHLNTLLGERPVQHREVQGNESDLFMSYFPRGLKYQEGGVESAFHK 127
Query: 389 VVTN-PGAEKRMFQVKGKRNVRVRQVDPLISSMNKGDCFILDINNDIYVYVGERTKNVEK 565
T P A K+++QVKGK+N+R + S N GDCFILD+ +I+ + G ++ +E+
Sbjct: 128 TSTGAPAAIKKLYQVKGKKNIRATERALNWDSFNTGDCFILDLGQNIFAWCGGKSNILER 187
Query: 566 LKAISMANQIRDQDHNGRGRVEII 637
KA +A IRD + G+ +VEI+
Sbjct: 188 NKARDLALAIRDSERQGKAQVEIV 211
>U80184-1|AAC02796.1| 1269|Homo sapiens FLII protein.
Length = 1269
Score = 144 bits (350), Expect = 2e-34
Identities = 73/201 (36%), Positives = 113/201 (56%)
Frame = +2
Query: 35 NAGRQAGVEIWRIQNFEPVAVQSKDFGKFYKGDSYIILKTTSDKRNNLSWDIHYWIGSET 214
+ G+ G+ IW+I+NF PV V+ GKFY+ D YI+LKT D +L+W+I+YWIG E
Sbjct: 494 DVGQLPGLTIWQIENFVPVLVEEAFHGKFYEADCYIVLKTFLDDSGSLNWEIYYWIGGEA 553
Query: 215 SQDEAGAAAILTVGLDDKFGGAAVQHREAMGHESNHFLQYFTSALQYLDGGNPSGFNHVV 394
+ D+ +AI V L + G RE MG ES FLQ F + + Y++GG SGF + V
Sbjct: 554 TLDKKACSAIHAVNLRNYLGAECRTVREEMGDESEEFLQVFDNDISYIEGGTASGF-YTV 612
Query: 395 TNPGAEKRMFQVKGKRNVRVRQVDPLISSMNKGDCFILDINNDIYVYVGERTKNVEKLKA 574
+ RM++V GK+N+++ V +S++ F+LD DIYV+ G + KA
Sbjct: 613 EDTHYVTRMYRVYGKKNIKLEPVPLKGTSLDPRFVFLLDRGLDIYVWRGAQATLSSTTKA 672
Query: 575 ISMANQIRDQDHNGRGRVEII 637
A +I + G+ + ++
Sbjct: 673 RLFAEKINKNERKGKAEITLL 693
Score = 31.9 bits (69), Expect = 2.0
Identities = 40/170 (23%), Positives = 67/170 (39%), Gaps = 5/170 (2%)
Frame = +2
Query: 143 ILKTTSDKRNNLSWDIHYWIGSETSQDEAGAAA-ILTVGLDDKFGGAAVQHREAMGHESN 319
ILK + +N ++ W+G + DEA A IL D + + G E
Sbjct: 1087 ILKVPFESEDNQGI-VYAWVGRASDPDEAKLAEDILNTMFDTSYSKQVINE----GEEPE 1141
Query: 320 HFLQYFTSALQYLDGGNPSGFNHVVTNPGAEKRMFQVKGKRNVRVRQVDPLISSMNKGDC 499
+F A + D + + EK F V K + D + D
Sbjct: 1142 NFFWVGIGAQKPYDDDAEYMKHTRLFRCSNEKGYFAVTEKCS------DFCQDDLADDDI 1195
Query: 500 FILDINNDIYVYVGERTKNVE---KLKAISMANQ-IRDQDHNGRGRVEII 637
+LD ++Y++VG +T VE LKA + Q +R ++H R+ ++
Sbjct: 1196 MLLDNGQEVYMWVGTQTSQVEIKLSLKACQVYIQHMRSKEHERPRRLRLV 1245
>U01184-1|AAC03568.1| 1268|Homo sapiens flightless-I homolog protein.
Length = 1268
Score = 144 bits (350), Expect = 2e-34
Identities = 73/201 (36%), Positives = 113/201 (56%)
Frame = +2
Query: 35 NAGRQAGVEIWRIQNFEPVAVQSKDFGKFYKGDSYIILKTTSDKRNNLSWDIHYWIGSET 214
+ G+ G+ IW+I+NF PV V+ GKFY+ D YI+LKT D +L+W+I+YWIG E
Sbjct: 493 DVGQLPGLTIWQIENFVPVLVEEAFHGKFYEADCYIVLKTFLDDSGSLNWEIYYWIGGEA 552
Query: 215 SQDEAGAAAILTVGLDDKFGGAAVQHREAMGHESNHFLQYFTSALQYLDGGNPSGFNHVV 394
+ D+ +AI V L + G RE MG ES FLQ F + + Y++GG SGF + V
Sbjct: 553 TLDKKACSAIHAVNLRNYLGAECRTVREEMGDESEEFLQVFDNDISYIEGGTASGF-YTV 611
Query: 395 TNPGAEKRMFQVKGKRNVRVRQVDPLISSMNKGDCFILDINNDIYVYVGERTKNVEKLKA 574
+ RM++V GK+N+++ V +S++ F+LD DIYV+ G + KA
Sbjct: 612 EDTHYVTRMYRVYGKKNIKLEPVPLKGTSLDPRFVFLLDRGLDIYVWRGAQATLSSTTKA 671
Query: 575 ISMANQIRDQDHNGRGRVEII 637
A +I + G+ + ++
Sbjct: 672 RLFAEKINKNERKGKAEITLL 692
Score = 31.9 bits (69), Expect = 2.0
Identities = 40/170 (23%), Positives = 67/170 (39%), Gaps = 5/170 (2%)
Frame = +2
Query: 143 ILKTTSDKRNNLSWDIHYWIGSETSQDEAGAAA-ILTVGLDDKFGGAAVQHREAMGHESN 319
ILK + +N ++ W+G + DEA A IL D + + G E
Sbjct: 1086 ILKVPFESEDNQGI-VYAWVGRASDPDEAKLAEDILNTMFDTSYSKQVINE----GEEPE 1140
Query: 320 HFLQYFTSALQYLDGGNPSGFNHVVTNPGAEKRMFQVKGKRNVRVRQVDPLISSMNKGDC 499
+F A + D + + EK F V K + D + D
Sbjct: 1141 NFFWVGIGAQKPYDDDAEYMKHTRLFRCSNEKGYFAVTEKCS------DFCQDDLADDDI 1194
Query: 500 FILDINNDIYVYVGERTKNVE---KLKAISMANQ-IRDQDHNGRGRVEII 637
+LD ++Y++VG +T VE LKA + Q +R ++H R+ ++
Sbjct: 1195 MLLDNGQEVYMWVGTQTSQVEIKLSLKACQVYIQHMRSKEHERPRRLRLV 1244
>BC025300-1|AAH25300.1| 1269|Homo sapiens flightless I homolog
(Drosophila) protein.
Length = 1269
Score = 144 bits (350), Expect = 2e-34
Identities = 73/201 (36%), Positives = 113/201 (56%)
Frame = +2
Query: 35 NAGRQAGVEIWRIQNFEPVAVQSKDFGKFYKGDSYIILKTTSDKRNNLSWDIHYWIGSET 214
+ G+ G+ IW+I+NF PV V+ GKFY+ D YI+LKT D +L+W+I+YWIG E
Sbjct: 494 DVGQLPGLTIWQIENFVPVLVEEAFHGKFYEADCYIVLKTFLDDSGSLNWEIYYWIGGEA 553
Query: 215 SQDEAGAAAILTVGLDDKFGGAAVQHREAMGHESNHFLQYFTSALQYLDGGNPSGFNHVV 394
+ D+ +AI V L + G RE MG ES FLQ F + + Y++GG SGF + V
Sbjct: 554 TLDKKACSAIHAVNLRNYLGAECRTVREEMGDESEEFLQVFDNDISYIEGGTASGF-YTV 612
Query: 395 TNPGAEKRMFQVKGKRNVRVRQVDPLISSMNKGDCFILDINNDIYVYVGERTKNVEKLKA 574
+ RM++V GK+N+++ V +S++ F+LD DIYV+ G + KA
Sbjct: 613 EDTHYVTRMYRVYGKKNIKLEPVPLKGTSLDPRFVFLLDRGLDIYVWRGAQATLSSTTKA 672
Query: 575 ISMANQIRDQDHNGRGRVEII 637
A +I + G+ + ++
Sbjct: 673 RLFAEKINKNERKGKAEITLL 693
Score = 31.9 bits (69), Expect = 2.0
Identities = 40/170 (23%), Positives = 67/170 (39%), Gaps = 5/170 (2%)
Frame = +2
Query: 143 ILKTTSDKRNNLSWDIHYWIGSETSQDEAGAAA-ILTVGLDDKFGGAAVQHREAMGHESN 319
ILK + +N ++ W+G + DEA A IL D + + G E
Sbjct: 1087 ILKVPFESEDNQGI-VYAWVGRASDPDEAKLAEDILNTMFDTSYSKQVINE----GEEPE 1141
Query: 320 HFLQYFTSALQYLDGGNPSGFNHVVTNPGAEKRMFQVKGKRNVRVRQVDPLISSMNKGDC 499
+F A + D + + EK F V K + D + D
Sbjct: 1142 NFFWVGIGAQKPYDDDAEYMKHTRLFRCSNEKGYFAVTEKCS------DFCQDDLADDDI 1195
Query: 500 FILDINNDIYVYVGERTKNVE---KLKAISMANQ-IRDQDHNGRGRVEII 637
+LD ++Y++VG +T VE LKA + Q +R ++H R+ ++
Sbjct: 1196 MLLDNGQEVYMWVGTQTSQVEIKLSLKACQVYIQHMRSKEHERPRRLRLV 1245
>AB208864-1|BAD92101.1| 1101|Homo sapiens flightless I homolog variant
protein.
Length = 1101
Score = 144 bits (350), Expect = 2e-34
Identities = 73/201 (36%), Positives = 113/201 (56%)
Frame = +2
Query: 35 NAGRQAGVEIWRIQNFEPVAVQSKDFGKFYKGDSYIILKTTSDKRNNLSWDIHYWIGSET 214
+ G+ G+ IW+I+NF PV V+ GKFY+ D YI+LKT D +L+W+I+YWIG E
Sbjct: 481 DVGQLPGLTIWQIENFVPVLVEEAFHGKFYEADCYIVLKTFLDDSGSLNWEIYYWIGGEA 540
Query: 215 SQDEAGAAAILTVGLDDKFGGAAVQHREAMGHESNHFLQYFTSALQYLDGGNPSGFNHVV 394
+ D+ +AI V L + G RE MG ES FLQ F + + Y++GG SGF + V
Sbjct: 541 TLDKKACSAIHAVNLRNYLGAECRTVREEMGDESEEFLQVFDNDISYIEGGTASGF-YTV 599
Query: 395 TNPGAEKRMFQVKGKRNVRVRQVDPLISSMNKGDCFILDINNDIYVYVGERTKNVEKLKA 574
+ RM++V GK+N+++ V +S++ F+LD DIYV+ G + KA
Sbjct: 600 EDTHYVTRMYRVYGKKNIKLEPVPLKGTSLDPRFVFLLDRGLDIYVWRGAQATLSSTTKA 659
Query: 575 ISMANQIRDQDHNGRGRVEII 637
A +I + G+ + ++
Sbjct: 660 RLFAEKINKNERKGKAEITLL 680
Score = 29.9 bits (64), Expect = 8.2
Identities = 39/161 (24%), Positives = 63/161 (39%), Gaps = 5/161 (3%)
Frame = +2
Query: 143 ILKTTSDKRNNLSWDIHYWIGSETSQDEAGAAA-ILTVGLDDKFGGAAVQHREAMGHESN 319
ILK + +N ++ W+G + DEA A IL D + + G E
Sbjct: 952 ILKVPFESEDNQGI-VYAWVGRASDPDEAKLAEDILNTMFDTSYSKQVINE----GEEPE 1006
Query: 320 HFLQYFTSALQYLDGGNPSGFNHVVTNPGAEKRMFQVKGKRNVRVRQVDPLISSMNKGDC 499
+F A + D + + EK F V K + D + D
Sbjct: 1007 NFFWVGIGAQKPYDDDAEYMKHTRLFRCSNEKGYFAVTEKCS------DFCQDDLADDDI 1060
Query: 500 FILDINNDIYVYVGERTKNVE---KLKAISMANQ-IRDQDH 610
+LD ++Y++VG +T VE LKA + Q +R ++H
Sbjct: 1061 MLLDNGQEVYMWVGTQTSQVEIKLSLKACQVYIQHMRSKEH 1101
>U12026-1|AAA92670.1| 172|Homo sapiens Cap-G protein.
Length = 172
Score = 137 bits (332), Expect = 3e-32
Identities = 66/163 (40%), Positives = 100/163 (61%), Gaps = 1/163 (0%)
Frame = +2
Query: 29 FANAGRQAGVEIWRIQNFEPVAVQSKDFGKFYKGDSYIILKTTSDKRNNLSWDIHYWIGS 208
F + + G+ +WR++ +PV V ++ G F+ GDSY++L ++ ++L H WIG
Sbjct: 12 FPGSVQDPGLHVWRVEKLKPVPVAQENQGVFFSGDSYLVLHNGPEEVSHL----HLWIGQ 67
Query: 209 ETSQDEAGAAAILTVGLDDKFGGAAVQHREAMGHESNHFLQYFTSALQYLDGGNPSGFNH 388
++S+DE GA A+L V L+ G VQHRE G+ES+ F+ YF L+Y +GG S F+
Sbjct: 68 QSSRDEQGACAVLAVHLNTLLGERPVQHREVQGNESDLFMSYFPRGLKYQEGGVESAFHK 127
Query: 389 VVTN-PGAEKRMFQVKGKRNVRVRQVDPLISSMNKGDCFILDI 514
T P A K+++QVKGK+N+R + S N GDCFILD+
Sbjct: 128 TSTGAPAAIKKLYQVKGKKNIRATERALNWDSFNTGDCFILDL 170
>AL513122-7|CAI14416.1| 485|Homo sapiens gelsolin (amyloidosis,
Finnish type) protein.
Length = 485
Score = 96.7 bits (230), Expect = 6e-20
Identities = 62/184 (33%), Positives = 87/184 (47%), Gaps = 2/184 (1%)
Frame = +2
Query: 59 EIWRIQNFEPVAVQSKDFGKFYKGDSYIILKTTSDKRNNLSWDIHYWIGSETSQDEAGAA 238
+IWRI+ V V +G+FY GDSYIIL I+ W G++++QDE A+
Sbjct: 179 QIWRIEGSNKVPVDPATYGQFYGGDSYIILYNYRHGGRQ-GQIIYNWQGAQSTQDEVAAS 237
Query: 239 AILTVGLDDKFGGAAVQHREAMGHESNHFLQYFTSALQYLDGGNPSGFNHVVTNPGAEKR 418
AILT LD++ GG VQ R G E H + F + G S T P A R
Sbjct: 238 AILTAQLDEELGGTPVQSRVVQGKEPAHLMSLFGGKPMIIYKGGTSR-EGGQTAP-ASTR 295
Query: 419 MFQVKGKRNVRVRQVD--PLISSMNKGDCFILDINNDIYVYVGERTKNVEKLKAISMANQ 592
+FQV+ R V+ P ++N D F+L + Y++VG EK A +
Sbjct: 296 LFQVRANSAGATRAVEVLPKAGALNSNDAFVLKTPSAAYLWVGTGASEAEKTGAQELLRV 355
Query: 593 IRDQ 604
+R Q
Sbjct: 356 LRAQ 359
>AK075198-1|BAC11465.1| 396|Homo sapiens protein ( Homo sapiens
cDNA FLJ90717 fis, clone PLACE1008657, highly similar to
Bovine mRNA for adseverin. ).
Length = 396
Score = 92.3 bits (219), Expect = 1e-18
Identities = 65/188 (34%), Positives = 97/188 (51%), Gaps = 7/188 (3%)
Frame = +2
Query: 56 VEIWRIQNFEPVAVQSKDFGKFYKGDSYIILKTTSDKRNNLSWDIHYWIGSETSQDEAGA 235
VEIWR++N + V +G+FY GD YIIL T R + I+ W G+ ++DE
Sbjct: 79 VEIWRVENNGRIQVDQNSYGEFYGGDCYIILYTYP--RGQI---IYTWQGANATRDELTT 133
Query: 236 AAILTVGLDDKFGGAAVQHREAMGHESNHFLQYFTS--ALQYLDGGNPSGFNHVVTNPGA 409
+A LTV LD GG AVQ R + G E H L F + Y +G + G P
Sbjct: 134 SAFLTVQLDRSLGGQAVQIRVSQGKEPVHLLSLFKDKPLIIYKNGTSKKGGQ----APAP 189
Query: 410 EKRMFQVKGKRNV----RVRQVDPLISSMNKGDCFILDI-NNDIYVYVGERTKNVEKLKA 574
R+FQV +RN+ R+ +VD +S+N D F+L + N Y++VG+ E+ A
Sbjct: 190 PTRLFQV--RRNLASITRIVEVDVDANSLNSNDVFVLKLPQNSGYIWVGKGASQEEEKGA 247
Query: 575 ISMANQIR 598
+A+ ++
Sbjct: 248 EYVASVLK 255
Score = 30.7 bits (66), Expect = 4.7
Identities = 12/44 (27%), Positives = 24/44 (54%)
Frame = +2
Query: 494 DCFILDINNDIYVYVGERTKNVEKLKAISMANQIRDQDHNGRGR 625
D +LD I++++G+ VEK +++ A + D +GR +
Sbjct: 325 DVMLLDAWEQIFIWIGKDANEVEKKESLKSAKMYLETDPSGRDK 368
>AK027778-1|BAB55361.1| 468|Homo sapiens protein ( Homo sapiens
cDNA FLJ14872 fis, clone PLACE1002655, highly similar to
ADSEVERIN. ).
Length = 468
Score = 92.3 bits (219), Expect = 1e-18
Identities = 65/188 (34%), Positives = 97/188 (51%), Gaps = 7/188 (3%)
Frame = +2
Query: 56 VEIWRIQNFEPVAVQSKDFGKFYKGDSYIILKTTSDKRNNLSWDIHYWIGSETSQDEAGA 235
VEIWR++N + V +G+FY GD YIIL T R + I+ W G+ ++DE
Sbjct: 151 VEIWRVENNGRIQVDQNSYGEFYGGDCYIILYTYP--RGQI---IYTWQGANATRDELTT 205
Query: 236 AAILTVGLDDKFGGAAVQHREAMGHESNHFLQYFTS--ALQYLDGGNPSGFNHVVTNPGA 409
+A LTV LD GG AVQ R + G E H L F + Y +G + G P
Sbjct: 206 SAFLTVQLDRSLGGQAVQIRVSQGKEPVHLLSLFKDKPLIIYKNGTSKKGGQ----APAP 261
Query: 410 EKRMFQVKGKRNV----RVRQVDPLISSMNKGDCFILDI-NNDIYVYVGERTKNVEKLKA 574
R+FQV +RN+ R+ +VD +S+N D F+L + N Y++VG+ E+ A
Sbjct: 262 PTRLFQV--RRNLASITRIVEVDVDANSLNSNDVFVLKLPQNSGYIWVGKGASQEEEKGA 319
Query: 575 ISMANQIR 598
+A+ ++
Sbjct: 320 EYVASVLK 327
Score = 30.7 bits (66), Expect = 4.7
Identities = 12/44 (27%), Positives = 24/44 (54%)
Frame = +2
Query: 494 DCFILDINNDIYVYVGERTKNVEKLKAISMANQIRDQDHNGRGR 625
D +LD I++++G+ VEK +++ A + D +GR +
Sbjct: 397 DVMLLDAWEQIFIWIGKDANEVEKKESLKSAKMYLETDPSGRDK 440
>X07066-1|CAA30102.1| 69|Homo sapiens protein ( Human gene for
gelsolin exon 4. ).
Length = 69
Score = 77.8 bits (183), Expect = 3e-14
Identities = 28/62 (45%), Positives = 44/62 (70%)
Frame = +2
Query: 20 HPAFANAGRQAGVEIWRIQNFEPVAVQSKDFGKFYKGDSYIILKTTSDKRNNLSWDIHYW 199
HP F AG++ G++IWR++ F+ V V + +G F+ GD+Y+ILKT + NL +D+HYW
Sbjct: 8 HPEFLKAGKEPGLQIWRVEKFDLVPVPTNLYGDFFTGDAYVILKTVQLRNGNLQYDLHYW 67
Query: 200 IG 205
+G
Sbjct: 68 LG 69
>D88154-1|BAA21668.1| 686|Homo sapiens villin-like protein protein.
Length = 686
Score = 73.3 bits (172), Expect = 7e-13
Identities = 49/165 (29%), Positives = 75/165 (45%), Gaps = 2/165 (1%)
Frame = +2
Query: 56 VEIWRIQNFEPVAVQSKDFGKFYKGDSYIILKTTSDKRNNLSWDIHYWIGSETSQDEAGA 235
VE+W IQ+ V K G+ G+ Y++L T + + + ++ W G + + DE A
Sbjct: 223 VEVWCIQDLHRQPVDPKRHGQLCAGNCYLVLYTYQ-RLGRVQYILYLWQGHQATADEIEA 281
Query: 236 AAILTVGLDDKFGGAAVQHREAMGHESNHFLQYFTSALQYLDGGNPSGFNHVVTNPGAEK 415
LD +GG VQ MG E HFL F L +G +H +
Sbjct: 282 LNSNAEELDVMYGGVLVQEHVTMGSEPPHFLAIFQGQLVIFQ--ERAG-HHGKGQSASTT 338
Query: 416 RMFQVKG--KRNVRVRQVDPLISSMNKGDCFILDINNDIYVYVGE 544
R+FQV+G N R +V SS+N D F+L + Y++ G+
Sbjct: 339 RLFQVQGTDSHNTRTMEVPARASSLNSSDIFLLVTASVCYLWFGK 383
>BC004300-1|AAH04300.1| 672|Homo sapiens VILL protein protein.
Length = 672
Score = 73.3 bits (172), Expect = 7e-13
Identities = 49/165 (29%), Positives = 75/165 (45%), Gaps = 2/165 (1%)
Frame = +2
Query: 56 VEIWRIQNFEPVAVQSKDFGKFYKGDSYIILKTTSDKRNNLSWDIHYWIGSETSQDEAGA 235
VE+W IQ+ V K G+ G+ Y++L T + + + ++ W G + + DE A
Sbjct: 209 VEVWCIQDLHRQPVDPKRHGQLCAGNCYLVLYTYQ-RLGRVQYILYLWQGHQATADEIEA 267
Query: 236 AAILTVGLDDKFGGAAVQHREAMGHESNHFLQYFTSALQYLDGGNPSGFNHVVTNPGAEK 415
LD +GG VQ MG E HFL F L +G +H +
Sbjct: 268 LNSNAEELDVMYGGVLVQEHVTMGSEPPHFLAIFQGQLVIFQ--ERAG-HHGKGQSASTT 324
Query: 416 RMFQVKG--KRNVRVRQVDPLISSMNKGDCFILDINNDIYVYVGE 544
R+FQV+G N R +V SS+N D F+L + Y++ G+
Sbjct: 325 RLFQVQGTDSHNTRTMEVPARASSLNSSDIFLLVTASVCYLWFGK 369
>BC000243-1|AAH00243.1| 686|Homo sapiens VILL protein protein.
Length = 686
Score = 73.3 bits (172), Expect = 7e-13
Identities = 49/165 (29%), Positives = 75/165 (45%), Gaps = 2/165 (1%)
Frame = +2
Query: 56 VEIWRIQNFEPVAVQSKDFGKFYKGDSYIILKTTSDKRNNLSWDIHYWIGSETSQDEAGA 235
VE+W IQ+ V K G+ G+ Y++L T + + + ++ W G + + DE A
Sbjct: 223 VEVWCIQDLHRQPVDPKRHGQLCAGNCYLVLYTYQ-RLGRVQYILYLWQGHQATADEIEA 281
Query: 236 AAILTVGLDDKFGGAAVQHREAMGHESNHFLQYFTSALQYLDGGNPSGFNHVVTNPGAEK 415
LD +GG VQ MG E HFL F L +G +H +
Sbjct: 282 LNSNAEELDVMYGGVLVQEHVTMGSEPPHFLAIFQGQLVIFQ--ERAG-HHGKGQSASTT 338
Query: 416 RMFQVKG--KRNVRVRQVDPLISSMNKGDCFILDINNDIYVYVGE 544
R+FQV+G N R +V SS+N D F+L + Y++ G+
Sbjct: 339 RLFQVQGTDSHNTRTMEVPARASSLNSSDIFLLVTASVCYLWFGK 383
>BC075797-1|AAH75797.1| 85|Homo sapiens Unknown (protein for
MGC:87550) protein.
Length = 85
Score = 65.3 bits (152), Expect = 2e-10
Identities = 26/62 (41%), Positives = 39/62 (62%)
Frame = +2
Query: 20 HPAFANAGRQAGVEIWRIQNFEPVAVQSKDFGKFYKGDSYIILKTTSDKRNNLSWDIHYW 199
H FA AG+QAG+++WRI+ E V V G FY GD+Y++L T R ++ +H+W
Sbjct: 7 HEEFARAGKQAGLQVWRIEKLELVPVPQSAHGDFYVGDAYLVLHTAKTSR-GFTYHLHFW 65
Query: 200 IG 205
+G
Sbjct: 66 LG 67
>BC017491-1|AAH17491.1| 285|Homo sapiens Similar to gelsolin
(amyloidosis, Finnish type) protein.
Length = 285
Score = 64.5 bits (150), Expect = 3e-10
Identities = 43/133 (32%), Positives = 61/133 (45%), Gaps = 2/133 (1%)
Frame = +2
Query: 212 TSQDEAGAAAILTVGLDDKFGGAAVQHREAMGHESNHFLQYFTSALQYLDGGNPSGFNHV 391
++QDE A+AILT LD++ GG VQ R G E H + F + G S
Sbjct: 1 STQDEVAASAILTAQLDEELGGTPVQSRVVQGKEPAHLMSLFGGKPMIIYKGGTSR-EGG 59
Query: 392 VTNPGAEKRMFQVKGKRNVRVRQVD--PLISSMNKGDCFILDINNDIYVYVGERTKNVEK 565
T P A R+FQV+ R V+ P ++N D F+L + Y++VG EK
Sbjct: 60 QTAP-ASTRLFQVRANSAGATRAVEVLPKAGALNSNDAFVLKTPSAAYLWVGTGASEAEK 118
Query: 566 LKAISMANQIRDQ 604
A + +R Q
Sbjct: 119 TGAQELLRVLRAQ 131
>AL160060-2|CAH71300.1| 2214|Homo sapiens supervillin protein.
Length = 2214
Score = 54.8 bits (126), Expect = 3e-07
Identities = 25/66 (37%), Positives = 42/66 (63%)
Frame = +2
Query: 419 MFQVKGKRNVRVRQVDPLISSMNKGDCFILDINNDIYVYVGERTKNVEKLKAISMANQIR 598
+ Q+KG+R+V+ R V+P S++N GDCF+L + +++VGE +EK KA +A I+
Sbjct: 1445 LLQIKGRRHVQTRLVEPRASALNSGDCFLLLSPHCCFLWVGEFANVIEKAKASELATLIQ 1504
Query: 599 DQDHNG 616
+ G
Sbjct: 1505 TKRELG 1510
Score = 47.6 bits (108), Expect = 4e-05
Identities = 50/202 (24%), Positives = 93/202 (46%), Gaps = 19/202 (9%)
Frame = +2
Query: 56 VEIWRIQNFEPVAVQSKDFGKFYKGDSYII-----LKTTSDKRNNLSWDIH--------- 193
V++W I F+ + + G+F++GD+Y++ + T R +
Sbjct: 1754 VDVWHILEFDYSRLPKQSIGQFHEGDAYVVKWKFMVSTAVGSRQKGEHSVRAAGKEKCVY 1813
Query: 194 -YWIGSETSQDEAGAAAILTVGLDDKFGGAAVQHREAMGHESNHFLQYFTSALQYLDGGN 370
+W G ++ E G +A++TV LD++ GA VQ G E FLQ F + G
Sbjct: 1814 FFWQGRHSTVSEKGTSALMTVELDEE-RGAQVQ--VLQGKEPPCFLQCFQGGMVVHSGRR 1870
Query: 371 PSGFNHVVTNPGAEKRMFQVKGKRNV--RVRQVDPLISSM-NKGDCFILDINND-IYVYV 538
N +E R++ V+G+ V + +V SS+ ++ +L++N IY++
Sbjct: 1871 ----EEEEENVQSEWRLYCVRGEVPVEGNLLEVACHCSSLRSRTSMVVLNVNKALIYLWH 1926
Query: 539 GERTKNVEKLKAISMANQIRDQ 604
G + + K + AN+I++Q
Sbjct: 1927 GCKAQAHTKEVGRTAANKIKEQ 1948
>AL160060-1|CAH71301.1| 1788|Homo sapiens supervillin protein.
Length = 1788
Score = 54.8 bits (126), Expect = 3e-07
Identities = 25/66 (37%), Positives = 42/66 (63%)
Frame = +2
Query: 419 MFQVKGKRNVRVRQVDPLISSMNKGDCFILDINNDIYVYVGERTKNVEKLKAISMANQIR 598
+ Q+KG+R+V+ R V+P S++N GDCF+L + +++VGE +EK KA +A I+
Sbjct: 1019 LLQIKGRRHVQTRLVEPRASALNSGDCFLLLSPHCCFLWVGEFANVIEKAKASELATLIQ 1078
Query: 599 DQDHNG 616
+ G
Sbjct: 1079 TKRELG 1084
Score = 47.6 bits (108), Expect = 4e-05
Identities = 50/202 (24%), Positives = 93/202 (46%), Gaps = 19/202 (9%)
Frame = +2
Query: 56 VEIWRIQNFEPVAVQSKDFGKFYKGDSYII-----LKTTSDKRNNLSWDIH--------- 193
V++W I F+ + + G+F++GD+Y++ + T R +
Sbjct: 1328 VDVWHILEFDYSRLPKQSIGQFHEGDAYVVKWKFMVSTAVGSRQKGEHSVRAAGKEKCVY 1387
Query: 194 -YWIGSETSQDEAGAAAILTVGLDDKFGGAAVQHREAMGHESNHFLQYFTSALQYLDGGN 370
+W G ++ E G +A++TV LD++ GA VQ G E FLQ F + G
Sbjct: 1388 FFWQGRHSTVSEKGTSALMTVELDEE-RGAQVQ--VLQGKEPPCFLQCFQGGMVVHSGRR 1444
Query: 371 PSGFNHVVTNPGAEKRMFQVKGKRNV--RVRQVDPLISSM-NKGDCFILDINND-IYVYV 538
N +E R++ V+G+ V + +V SS+ ++ +L++N IY++
Sbjct: 1445 ----EEEEENVQSEWRLYCVRGEVPVEGNLLEVACHCSSLRSRTSMVVLNVNKALIYLWH 1500
Query: 539 GERTKNVEKLKAISMANQIRDQ 604
G + + K + AN+I++Q
Sbjct: 1501 GCKAQAHTKEVGRTAANKIKEQ 1522
>AL158167-3|CAI15237.1| 2214|Homo sapiens supervillin protein.
Length = 2214
Score = 54.8 bits (126), Expect = 3e-07
Identities = 25/66 (37%), Positives = 42/66 (63%)
Frame = +2
Query: 419 MFQVKGKRNVRVRQVDPLISSMNKGDCFILDINNDIYVYVGERTKNVEKLKAISMANQIR 598
+ Q+KG+R+V+ R V+P S++N GDCF+L + +++VGE +EK KA +A I+
Sbjct: 1445 LLQIKGRRHVQTRLVEPRASALNSGDCFLLLSPHCCFLWVGEFANVIEKAKASELATLIQ 1504
Query: 599 DQDHNG 616
+ G
Sbjct: 1505 TKRELG 1510
Score = 47.6 bits (108), Expect = 4e-05
Identities = 50/202 (24%), Positives = 93/202 (46%), Gaps = 19/202 (9%)
Frame = +2
Query: 56 VEIWRIQNFEPVAVQSKDFGKFYKGDSYII-----LKTTSDKRNNLSWDIH--------- 193
V++W I F+ + + G+F++GD+Y++ + T R +
Sbjct: 1754 VDVWHILEFDYSRLPKQSIGQFHEGDAYVVKWKFMVSTAVGSRQKGEHSVRAAGKEKCVY 1813
Query: 194 -YWIGSETSQDEAGAAAILTVGLDDKFGGAAVQHREAMGHESNHFLQYFTSALQYLDGGN 370
+W G ++ E G +A++TV LD++ GA VQ G E FLQ F + G
Sbjct: 1814 FFWQGRHSTVSEKGTSALMTVELDEE-RGAQVQ--VLQGKEPPCFLQCFQGGMVVHSGRR 1870
Query: 371 PSGFNHVVTNPGAEKRMFQVKGKRNV--RVRQVDPLISSM-NKGDCFILDINND-IYVYV 538
N +E R++ V+G+ V + +V SS+ ++ +L++N IY++
Sbjct: 1871 ----EEEEENVQSEWRLYCVRGEVPVEGNLLEVACHCSSLRSRTSMVVLNVNKALIYLWH 1926
Query: 539 GERTKNVEKLKAISMANQIRDQ 604
G + + K + AN+I++Q
Sbjct: 1927 GCKAQAHTKEVGRTAANKIKEQ 1948
>AL158167-2|CAI15236.1| 1788|Homo sapiens supervillin protein.
Length = 1788
Score = 54.8 bits (126), Expect = 3e-07
Identities = 25/66 (37%), Positives = 42/66 (63%)
Frame = +2
Query: 419 MFQVKGKRNVRVRQVDPLISSMNKGDCFILDINNDIYVYVGERTKNVEKLKAISMANQIR 598
+ Q+KG+R+V+ R V+P S++N GDCF+L + +++VGE +EK KA +A I+
Sbjct: 1019 LLQIKGRRHVQTRLVEPRASALNSGDCFLLLSPHCCFLWVGEFANVIEKAKASELATLIQ 1078
Query: 599 DQDHNG 616
+ G
Sbjct: 1079 TKRELG 1084
Score = 47.6 bits (108), Expect = 4e-05
Identities = 50/202 (24%), Positives = 93/202 (46%), Gaps = 19/202 (9%)
Frame = +2
Query: 56 VEIWRIQNFEPVAVQSKDFGKFYKGDSYII-----LKTTSDKRNNLSWDIH--------- 193
V++W I F+ + + G+F++GD+Y++ + T R +
Sbjct: 1328 VDVWHILEFDYSRLPKQSIGQFHEGDAYVVKWKFMVSTAVGSRQKGEHSVRAAGKEKCVY 1387
Query: 194 -YWIGSETSQDEAGAAAILTVGLDDKFGGAAVQHREAMGHESNHFLQYFTSALQYLDGGN 370
+W G ++ E G +A++TV LD++ GA VQ G E FLQ F + G
Sbjct: 1388 FFWQGRHSTVSEKGTSALMTVELDEE-RGAQVQ--VLQGKEPPCFLQCFQGGMVVHSGRR 1444
Query: 371 PSGFNHVVTNPGAEKRMFQVKGKRNV--RVRQVDPLISSM-NKGDCFILDINND-IYVYV 538
N +E R++ V+G+ V + +V SS+ ++ +L++N IY++
Sbjct: 1445 ----EEEEENVQSEWRLYCVRGEVPVEGNLLEVACHCSSLRSRTSMVVLNVNKALIYLWH 1500
Query: 539 GERTKNVEKLKAISMANQIRDQ 604
G + + K + AN+I++Q
Sbjct: 1501 GCKAQAHTKEVGRTAANKIKEQ 1522
>AF109135-1|AAD14682.1| 2214|Homo sapiens archvillin protein.
Length = 2214
Score = 54.8 bits (126), Expect = 3e-07
Identities = 25/66 (37%), Positives = 42/66 (63%)
Frame = +2
Query: 419 MFQVKGKRNVRVRQVDPLISSMNKGDCFILDINNDIYVYVGERTKNVEKLKAISMANQIR 598
+ Q+KG+R+V+ R V+P S++N GDCF+L + +++VGE +EK KA +A I+
Sbjct: 1445 LLQIKGRRHVQTRLVEPRASALNSGDCFLLLSPHCCFLWVGEFANVIEKAKASELATLIQ 1504
Query: 599 DQDHNG 616
+ G
Sbjct: 1505 TKRELG 1510
Score = 47.6 bits (108), Expect = 4e-05
Identities = 50/202 (24%), Positives = 93/202 (46%), Gaps = 19/202 (9%)
Frame = +2
Query: 56 VEIWRIQNFEPVAVQSKDFGKFYKGDSYII-----LKTTSDKRNNLSWDIH--------- 193
V++W I F+ + + G+F++GD+Y++ + T R +
Sbjct: 1754 VDVWHILEFDYSRLPKQSIGQFHEGDAYVVKWKFMVSTAVGSRQKGEHSVRAAGKEKCVY 1813
Query: 194 -YWIGSETSQDEAGAAAILTVGLDDKFGGAAVQHREAMGHESNHFLQYFTSALQYLDGGN 370
+W G ++ E G +A++TV LD++ GA VQ G E FLQ F + G
Sbjct: 1814 FFWQGRHSTVSEKGTSALMTVELDEE-RGAQVQ--VLQGKEPPCFLQCFQGGMVVHSGRR 1870
Query: 371 PSGFNHVVTNPGAEKRMFQVKGKRNV--RVRQVDPLISSM-NKGDCFILDINND-IYVYV 538
N +E R++ V+G+ V + +V SS+ ++ +L++N IY++
Sbjct: 1871 ----EEEEENVQSEWRLYCVRGEVPVEGNLLEVACHCSSLRSRTSMVVLNVNKALIYLWH 1926
Query: 539 GERTKNVEKLKAISMANQIRDQ 604
G + + K + AN+I++Q
Sbjct: 1927 GCKAQAHTKEVGRTAANKIKEQ 1948
>AF051851-1|AAC64696.1| 1788|Homo sapiens supervillin protein.
Length = 1788
Score = 54.8 bits (126), Expect = 3e-07
Identities = 25/66 (37%), Positives = 42/66 (63%)
Frame = +2
Query: 419 MFQVKGKRNVRVRQVDPLISSMNKGDCFILDINNDIYVYVGERTKNVEKLKAISMANQIR 598
+ Q+KG+R+V+ R V+P S++N GDCF+L + +++VGE +EK KA +A I+
Sbjct: 1019 LLQIKGRRHVQTRLVEPRASALNSGDCFLLLSPHCCFLWVGEFANVIEKAKASELATLIQ 1078
Query: 599 DQDHNG 616
+ G
Sbjct: 1079 TKRELG 1084
Score = 47.6 bits (108), Expect = 4e-05
Identities = 50/202 (24%), Positives = 93/202 (46%), Gaps = 19/202 (9%)
Frame = +2
Query: 56 VEIWRIQNFEPVAVQSKDFGKFYKGDSYII-----LKTTSDKRNNLSWDIH--------- 193
V++W I F+ + + G+F++GD+Y++ + T R +
Sbjct: 1328 VDVWHILEFDYSRLPKQSIGQFHEGDAYVVKWKFMVSTAVGSRQKGEHSVRAAGKEKCVY 1387
Query: 194 -YWIGSETSQDEAGAAAILTVGLDDKFGGAAVQHREAMGHESNHFLQYFTSALQYLDGGN 370
+W G ++ E G +A++TV LD++ GA VQ G E FLQ F + G
Sbjct: 1388 FFWQGRHSTVSEKGTSALMTVELDEE-RGAQVQ--VLQGKEPPCFLQCFQGGMVVHSGRR 1444
Query: 371 PSGFNHVVTNPGAEKRMFQVKGKRNV--RVRQVDPLISSM-NKGDCFILDINND-IYVYV 538
N +E R++ V+G+ V + +V SS+ ++ +L++N IY++
Sbjct: 1445 ----EEEEENVQSEWRLYCVRGEVPVEGNLLEVACHCSSLRSRTSMVVLNVNKALIYLWH 1500
Query: 539 GERTKNVEKLKAISMANQIRDQ 604
G + + K + AN+I++Q
Sbjct: 1501 GCKAQAHTKEVGRTAANKIKEQ 1522
>AF051850-1|AAC64695.1| 1788|Homo sapiens supervillin protein.
Length = 1788
Score = 54.8 bits (126), Expect = 3e-07
Identities = 25/66 (37%), Positives = 42/66 (63%)
Frame = +2
Query: 419 MFQVKGKRNVRVRQVDPLISSMNKGDCFILDINNDIYVYVGERTKNVEKLKAISMANQIR 598
+ Q+KG+R+V+ R V+P S++N GDCF+L + +++VGE +EK KA +A I+
Sbjct: 1019 LLQIKGRRHVQTRLVEPRASALNSGDCFLLLSPHCCFLWVGEFANVIEKAKASELATLIQ 1078
Query: 599 DQDHNG 616
+ G
Sbjct: 1079 TKRELG 1084
Score = 47.6 bits (108), Expect = 4e-05
Identities = 50/202 (24%), Positives = 93/202 (46%), Gaps = 19/202 (9%)
Frame = +2
Query: 56 VEIWRIQNFEPVAVQSKDFGKFYKGDSYII-----LKTTSDKRNNLSWDIH--------- 193
V++W I F+ + + G+F++GD+Y++ + T R +
Sbjct: 1328 VDVWHILEFDYSRLPKQSIGQFHEGDAYVVKWKFMVSTAVGSRQKGEHSVRAAGKEKCVY 1387
Query: 194 -YWIGSETSQDEAGAAAILTVGLDDKFGGAAVQHREAMGHESNHFLQYFTSALQYLDGGN 370
+W G ++ E G +A++TV LD++ GA VQ G E FLQ F + G
Sbjct: 1388 FFWQGRHSTVSEKGTSALMTVELDEE-RGAQVQ--VLQGKEPPCFLQCFQGGMVVHSGRR 1444
Query: 371 PSGFNHVVTNPGAEKRMFQVKGKRNV--RVRQVDPLISSM-NKGDCFILDINND-IYVYV 538
N +E R++ V+G+ V + +V SS+ ++ +L++N IY++
Sbjct: 1445 ----EEEEENVQSEWRLYCVRGEVPVEGNLLEVACHCSSLRSRTSMVVLNVNKALIYLWH 1500
Query: 539 GERTKNVEKLKAISMANQIRDQ 604
G + + K + AN+I++Q
Sbjct: 1501 GCKAQAHTKEVGRTAANKIKEQ 1522
>Y08612-1|CAA69904.1| 741|Homo sapiens 88kDa nuclear pore complex
protein protein.
Length = 741
Score = 32.7 bits (71), Expect = 1.2
Identities = 17/49 (34%), Positives = 24/49 (48%)
Frame = -2
Query: 387 WLKPDGLPPSKYCSADVKYCRKWLLSWPIASRCCTAAPPNLSSRPTVKM 241
W+ PD L P+ C C L WP+ S A+PP L +R V++
Sbjct: 470 WIVPDILGPTMICITSTYEC----LIWPLLSTVHPASPPLLCTREDVEV 514
>BC000335-1|AAH00335.1| 741|Homo sapiens nucleoporin 88kDa protein.
Length = 741
Score = 32.7 bits (71), Expect = 1.2
Identities = 17/49 (34%), Positives = 24/49 (48%)
Frame = -2
Query: 387 WLKPDGLPPSKYCSADVKYCRKWLLSWPIASRCCTAAPPNLSSRPTVKM 241
W+ PD L P+ C C L WP+ S A+PP L +R V++
Sbjct: 470 WIVPDILGPTMICITSTYEC----LIWPLLSTVHPASPPLLCTREDVEV 514
Database: human
Posted date: Oct 23, 2007 1:18 PM
Number of letters in database: 76,859,062
Number of sequences in database: 237,096
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 100,909,213
Number of Sequences: 237096
Number of extensions: 2398510
Number of successful extensions: 4035
Number of sequences better than 10.0: 43
Number of HSP's better than 10.0 without gapping: 3778
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 3958
length of database: 76,859,062
effective HSP length: 87
effective length of database: 56,231,710
effective search space used: 7253890590
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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