Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= I10A02NGRL0005_E13
(622 letters)
Database: human
237,096 sequences; 76,859,062 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
X70476-1|CAA49900.1| 906|Homo sapiens subunit of coatomer compl... 208 1e-53
BC000326-1|AAH00326.1| 906|Homo sapiens coatomer protein comple... 208 1e-53
BC038447-1|AAH38447.1| 1233|Homo sapiens COPA protein protein. 40 0.007
AL513282-3|CAI12455.1| 1233|Homo sapiens coatomer protein comple... 40 0.007
AL513282-2|CAI12454.1| 1224|Homo sapiens coatomer protein comple... 40 0.007
AL445230-2|CAI15004.1| 1233|Homo sapiens coatomer protein comple... 40 0.007
AL445230-1|CAI15005.1| 1224|Homo sapiens coatomer protein comple... 40 0.007
U24105-1|AAB70879.1| 1224|Homo sapiens coatomer protein protein. 39 0.016
BC093777-1|AAH93777.1| 930|Homo sapiens ADAM metallopeptidase w... 31 3.3
BC093775-1|AAH93775.1| 930|Homo sapiens ADAM metallopeptidase w... 31 3.3
AP001697-2|BAA95503.1| 517|Homo sapiens disintegrin-like and me... 31 3.3
AF142099-1|AAD49577.1| 930|Homo sapiens aggrecanase-2 protein. 31 3.3
AF141293-1|AAF02493.1| 518|Homo sapiens ADAMTS5 protein protein. 30 7.6
>X70476-1|CAA49900.1| 906|Homo sapiens subunit of coatomer complex
protein.
Length = 906
Score = 208 bits (508), Expect = 1e-53
Identities = 107/207 (51%), Positives = 136/207 (65%)
Frame = +2
Query: 2 LNDKELNIISYSLLVSVLEYQTAVMRGDFETADRVLPTVPHDQRTRVAHFLEKQGFKQQA 181
L DKELNIISYSLLVSVLEYQTAVMR DF AD+VLPT+P +QRTRVAHFLEKQGFKQQA
Sbjct: 575 LGDKELNIISYSLLVSVLEYQTAVMRRDFSMADKVLPTIPKEQRTRVAHFLEKQGFKQQA 634
Query: 182 LAVSTEPEHQFELALSLGELHXXXXXXXXXXXXXXXXXXXXXARWSKLGTXXXXXXDTEL 361
L VST+PEH+FELAL LGEL +W +L L
Sbjct: 635 LTVSTDPEHRFELALQLGEL---------KIAYQLAVEAESEQKWKQLAELAISKCQFGL 685
Query: 362 TKICYQNARDYSALLLFAVSIGDKELLQQVAQVSSEHGDDXIAFVAYFTLNELDSCLELL 541
+ C +A+DY LLL A + G+ ++ ++A+ + G + +AF++YF ++D+CLELL
Sbjct: 686 AQECLHHAQDYGGLLLLATASGNANMVNKLAEGAERDGKNNVAFMSYFLQGKVDACLELL 745
Query: 542 ISRGTISEAALFARSYVPSKVCEVVKL 622
I G + EAA AR+Y+PS+V VVKL
Sbjct: 746 IRTGRLPEAAFLARTYLPSQVSRVVKL 772
>BC000326-1|AAH00326.1| 906|Homo sapiens coatomer protein complex,
subunit beta 2 (beta prime) protein.
Length = 906
Score = 208 bits (508), Expect = 1e-53
Identities = 107/207 (51%), Positives = 136/207 (65%)
Frame = +2
Query: 2 LNDKELNIISYSLLVSVLEYQTAVMRGDFETADRVLPTVPHDQRTRVAHFLEKQGFKQQA 181
L DKELNIISYSLLVSVLEYQTAVMR DF AD+VLPT+P +QRTRVAHFLEKQGFKQQA
Sbjct: 575 LGDKELNIISYSLLVSVLEYQTAVMRRDFSMADKVLPTIPKEQRTRVAHFLEKQGFKQQA 634
Query: 182 LAVSTEPEHQFELALSLGELHXXXXXXXXXXXXXXXXXXXXXARWSKLGTXXXXXXDTEL 361
L VST+PEH+FELAL LGEL +W +L L
Sbjct: 635 LTVSTDPEHRFELALQLGEL---------KIAYQLAVEAESEQKWKQLAELAISKCQFGL 685
Query: 362 TKICYQNARDYSALLLFAVSIGDKELLQQVAQVSSEHGDDXIAFVAYFTLNELDSCLELL 541
+ C +A+DY LLL A + G+ ++ ++A+ + G + +AF++YF ++D+CLELL
Sbjct: 686 AQECLHHAQDYGGLLLLATASGNANMVNKLAEGAERDGKNNVAFMSYFLQGKVDACLELL 745
Query: 542 ISRGTISEAALFARSYVPSKVCEVVKL 622
I G + EAA AR+Y+PS+V VVKL
Sbjct: 746 IRTGRLPEAAFLARTYLPSQVSRVVKL 772
>BC038447-1|AAH38447.1| 1233|Homo sapiens COPA protein protein.
Length = 1233
Score = 39.9 bits (89), Expect = 0.007
Identities = 31/157 (19%), Positives = 66/157 (42%)
Frame = +2
Query: 149 FLEKQGFKQQALAVSTEPEHQFELALSLGELHXXXXXXXXXXXXXXXXXXXXXARWSKLG 328
+L+K+G+ + AL + + +F LAL G + W KLG
Sbjct: 637 YLQKKGYPEVALHFVKDEKTRFSLALECGNIEIALEAAKALDDKNC---------WEKLG 687
Query: 329 TXXXXXXDTELTKICYQNARDYSALLLFAVSIGDKELLQQVAQVSSEHGDDXIAFVAYFT 508
+ ++ ++CYQ +++ L + G+ E L+++ +++ D +
Sbjct: 688 EVALLQGNHQIVEMCYQRTKNFDKLSFLYLITGNLEKLRKMMKIAEIRKDMSGHYQNALY 747
Query: 509 LNELDSCLELLISRGTISEAALFARSYVPSKVCEVVK 619
L ++ + +L + G S A L A ++ + E +K
Sbjct: 748 LGDVSERVRILKNCGQKSLAYLTAATHGLDEEAESLK 784
>AL513282-3|CAI12455.1| 1233|Homo sapiens coatomer protein complex,
subunit alpha protein.
Length = 1233
Score = 39.9 bits (89), Expect = 0.007
Identities = 31/157 (19%), Positives = 66/157 (42%)
Frame = +2
Query: 149 FLEKQGFKQQALAVSTEPEHQFELALSLGELHXXXXXXXXXXXXXXXXXXXXXARWSKLG 328
+L+K+G+ + AL + + +F LAL G + W KLG
Sbjct: 637 YLQKKGYPEVALHFVKDEKTRFSLALECGNIEIALEAAKALDDKNC---------WEKLG 687
Query: 329 TXXXXXXDTELTKICYQNARDYSALLLFAVSIGDKELLQQVAQVSSEHGDDXIAFVAYFT 508
+ ++ ++CYQ +++ L + G+ E L+++ +++ D +
Sbjct: 688 EVALLQGNHQIVEMCYQRTKNFDKLSFLYLITGNLEKLRKMMKIAEIRKDMSGHYQNALY 747
Query: 509 LNELDSCLELLISRGTISEAALFARSYVPSKVCEVVK 619
L ++ + +L + G S A L A ++ + E +K
Sbjct: 748 LGDVSERVRILKNCGQKSLAYLTAATHGLDEEAESLK 784
>AL513282-2|CAI12454.1| 1224|Homo sapiens coatomer protein complex,
subunit alpha protein.
Length = 1224
Score = 39.9 bits (89), Expect = 0.007
Identities = 31/157 (19%), Positives = 66/157 (42%)
Frame = +2
Query: 149 FLEKQGFKQQALAVSTEPEHQFELALSLGELHXXXXXXXXXXXXXXXXXXXXXARWSKLG 328
+L+K+G+ + AL + + +F LAL G + W KLG
Sbjct: 628 YLQKKGYPEVALHFVKDEKTRFSLALECGNIEIALEAAKALDDKNC---------WEKLG 678
Query: 329 TXXXXXXDTELTKICYQNARDYSALLLFAVSIGDKELLQQVAQVSSEHGDDXIAFVAYFT 508
+ ++ ++CYQ +++ L + G+ E L+++ +++ D +
Sbjct: 679 EVALLQGNHQIVEMCYQRTKNFDKLSFLYLITGNLEKLRKMMKIAEIRKDMSGHYQNALY 738
Query: 509 LNELDSCLELLISRGTISEAALFARSYVPSKVCEVVK 619
L ++ + +L + G S A L A ++ + E +K
Sbjct: 739 LGDVSERVRILKNCGQKSLAYLTAATHGLDEEAESLK 775
>AL445230-2|CAI15004.1| 1233|Homo sapiens coatomer protein complex,
subunit alpha protein.
Length = 1233
Score = 39.9 bits (89), Expect = 0.007
Identities = 31/157 (19%), Positives = 66/157 (42%)
Frame = +2
Query: 149 FLEKQGFKQQALAVSTEPEHQFELALSLGELHXXXXXXXXXXXXXXXXXXXXXARWSKLG 328
+L+K+G+ + AL + + +F LAL G + W KLG
Sbjct: 637 YLQKKGYPEVALHFVKDEKTRFSLALECGNIEIALEAAKALDDKNC---------WEKLG 687
Query: 329 TXXXXXXDTELTKICYQNARDYSALLLFAVSIGDKELLQQVAQVSSEHGDDXIAFVAYFT 508
+ ++ ++CYQ +++ L + G+ E L+++ +++ D +
Sbjct: 688 EVALLQGNHQIVEMCYQRTKNFDKLSFLYLITGNLEKLRKMMKIAEIRKDMSGHYQNALY 747
Query: 509 LNELDSCLELLISRGTISEAALFARSYVPSKVCEVVK 619
L ++ + +L + G S A L A ++ + E +K
Sbjct: 748 LGDVSERVRILKNCGQKSLAYLTAATHGLDEEAESLK 784
>AL445230-1|CAI15005.1| 1224|Homo sapiens coatomer protein complex,
subunit alpha protein.
Length = 1224
Score = 39.9 bits (89), Expect = 0.007
Identities = 31/157 (19%), Positives = 66/157 (42%)
Frame = +2
Query: 149 FLEKQGFKQQALAVSTEPEHQFELALSLGELHXXXXXXXXXXXXXXXXXXXXXARWSKLG 328
+L+K+G+ + AL + + +F LAL G + W KLG
Sbjct: 628 YLQKKGYPEVALHFVKDEKTRFSLALECGNIEIALEAAKALDDKNC---------WEKLG 678
Query: 329 TXXXXXXDTELTKICYQNARDYSALLLFAVSIGDKELLQQVAQVSSEHGDDXIAFVAYFT 508
+ ++ ++CYQ +++ L + G+ E L+++ +++ D +
Sbjct: 679 EVALLQGNHQIVEMCYQRTKNFDKLSFLYLITGNLEKLRKMMKIAEIRKDMSGHYQNALY 738
Query: 509 LNELDSCLELLISRGTISEAALFARSYVPSKVCEVVK 619
L ++ + +L + G S A L A ++ + E +K
Sbjct: 739 LGDVSERVRILKNCGQKSLAYLTAATHGLDEEAESLK 775
>U24105-1|AAB70879.1| 1224|Homo sapiens coatomer protein protein.
Length = 1224
Score = 38.7 bits (86), Expect = 0.016
Identities = 30/157 (19%), Positives = 66/157 (42%)
Frame = +2
Query: 149 FLEKQGFKQQALAVSTEPEHQFELALSLGELHXXXXXXXXXXXXXXXXXXXXXARWSKLG 328
+L+K+G+ + AL + + +F LAL G + W KLG
Sbjct: 628 YLQKKGYPEVALHFVKDEKTRFSLALECGNIEIALEAAKALDDKNC---------WEKLG 678
Query: 329 TXXXXXXDTELTKICYQNARDYSALLLFAVSIGDKELLQQVAQVSSEHGDDXIAFVAYFT 508
+ ++ ++CYQ +++ + + G+ E L+++ +++ D +
Sbjct: 679 EVALLQGNHQIVEMCYQRTKNFDKVSFLYLITGNLEKLRKMMKIAEIRKDMSGHYQNALY 738
Query: 509 LNELDSCLELLISRGTISEAALFARSYVPSKVCEVVK 619
L ++ + +L + G S A L A ++ + E +K
Sbjct: 739 LGDVSERVRILKNCGQKSLAYLTAATHGLDEEAESLK 775
>BC093777-1|AAH93777.1| 930|Homo sapiens ADAM metallopeptidase with
thrombospondin type 1 motif, 5 (aggrecanase-2) protein.
Length = 930
Score = 31.1 bits (67), Expect = 3.3
Identities = 10/28 (35%), Positives = 17/28 (60%)
Frame = -2
Query: 243 CNSPSDRASSNWCSGSVDTAKACCLKPC 160
CN+P+ R + +C+G ++C L PC
Sbjct: 594 CNNPAPRNNGRYCTGKRAIYRSCSLMPC 621
>BC093775-1|AAH93775.1| 930|Homo sapiens ADAM metallopeptidase with
thrombospondin type 1 motif, 5 (aggrecanase-2) protein.
Length = 930
Score = 31.1 bits (67), Expect = 3.3
Identities = 10/28 (35%), Positives = 17/28 (60%)
Frame = -2
Query: 243 CNSPSDRASSNWCSGSVDTAKACCLKPC 160
CN+P+ R + +C+G ++C L PC
Sbjct: 594 CNNPAPRNNGRYCTGKRAIYRSCSLMPC 621
>AP001697-2|BAA95503.1| 517|Homo sapiens disintegrin-like and
metalloprotease with thrombospondin type 1 motif, 5
protein.
Length = 517
Score = 31.1 bits (67), Expect = 3.3
Identities = 10/28 (35%), Positives = 17/28 (60%)
Frame = -2
Query: 243 CNSPSDRASSNWCSGSVDTAKACCLKPC 160
CN+P+ R + +C+G ++C L PC
Sbjct: 181 CNNPAPRNNGRYCTGKRAIYRSCSLMPC 208
>AF142099-1|AAD49577.1| 930|Homo sapiens aggrecanase-2 protein.
Length = 930
Score = 31.1 bits (67), Expect = 3.3
Identities = 10/28 (35%), Positives = 17/28 (60%)
Frame = -2
Query: 243 CNSPSDRASSNWCSGSVDTAKACCLKPC 160
CN+P+ R + +C+G ++C L PC
Sbjct: 594 CNNPAPRNNGRYCTGKRAIYRSCSLMPC 621
>AF141293-1|AAF02493.1| 518|Homo sapiens ADAMTS5 protein protein.
Length = 518
Score = 29.9 bits (64), Expect = 7.6
Identities = 10/28 (35%), Positives = 16/28 (57%)
Frame = -2
Query: 243 CNSPSDRASSNWCSGSVDTAKACCLKPC 160
CN+P+ R + +C+G +C L PC
Sbjct: 182 CNNPAPRNNGRYCTGKRAIYHSCSLMPC 209
Database: human
Posted date: Oct 23, 2007 1:18 PM
Number of letters in database: 76,859,062
Number of sequences in database: 237,096
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 79,496,911
Number of Sequences: 237096
Number of extensions: 1459653
Number of successful extensions: 2843
Number of sequences better than 10.0: 13
Number of HSP's better than 10.0 without gapping: 2708
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 2841
length of database: 76,859,062
effective HSP length: 87
effective length of database: 56,231,710
effective search space used: 6691573490
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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