Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= I10A02NGRL0005_C14
(507 letters)
Database: human
237,096 sequences; 76,859,062 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
L37418-1|AAB59629.1| 453|Homo sapiens dihydrolipoamide succinyl... 197 2e-50
D26535-1|BAA05536.1| 453|Homo sapiens dihydrolipoamide succinyl... 197 2e-50
CR456727-1|CAG33008.1| 453|Homo sapiens DLST protein. 197 2e-50
BC001922-1|AAH01922.1| 453|Homo sapiens dihydrolipoamide S-succ... 197 2e-50
BC000302-1|AAH00302.1| 453|Homo sapiens dihydrolipoamide S-succ... 197 2e-50
AC006530-2|AAD30181.1| 453|Homo sapiens alpha-KG-E2 protein. 197 2e-50
D16373-1|BAA03871.1| 453|Homo sapiens mitochondrial dihydrolipo... 194 2e-49
S72422-1|AAB31066.1| 451|Homo sapiens alpha-ketoglutarate dehyd... 182 5e-46
Y00978-1|CAA68787.1| 615|Homo sapiens PDC-E2 precursor (AA -54 ... 91 2e-18
J03866-1|AAA62253.1| 613|Homo sapiens dihydrolipoamide acetyltr... 91 2e-18
BC039084-1|AAH39084.1| 647|Homo sapiens dihydrolipoamide S-acet... 91 2e-18
AK223596-1|BAD97316.1| 647|Homo sapiens dihydrolipoamide S-acet... 91 2e-18
Y13145-1|CAA73606.1| 501|Homo sapiens protein X protein. 87 3e-17
U82328-1|AAC39661.1| 501|Homo sapiens pyruvate dehydrogenase co... 87 3e-17
U79296-1|AAB50223.1| 375|Homo sapiens dihyrolipoamide acetyl tr... 87 3e-17
AJ298105-1|CAC18649.1| 501|Homo sapiens lipoyl-containing compo... 87 3e-17
AF001437-1|AAB66315.1| 501|Homo sapiens dihydrolipoamide dehydr... 87 3e-17
BC010389-1|AAH10389.1| 501|Homo sapiens pyruvate dehydrogenase ... 87 4e-17
X66785-1|CAA47285.1| 482|Homo sapiens transacylase protein. 74 3e-13
J03208-1|AAA35589.1| 477|Homo sapiens protein ( Human branched ... 74 3e-13
BT007372-1|AAP36036.1| 482|Homo sapiens dihydrolipoamide branch... 74 3e-13
BC016675-1|AAH16675.1| 482|Homo sapiens dihydrolipoamide branch... 74 3e-13
M27093-1|AAA64512.1| 477|Homo sapiens dihydrolipoyl transacylas... 73 6e-13
AL445928-9|CAH72257.1| 482|Homo sapiens dihydrolipoamide branch... 72 1e-12
X13822-1|CAA32052.1| 220|Homo sapiens dihydrolipoamide S-acetyl... 35 0.19
Z73359-2|CAC94789.1| 137|Homo sapiens 92M18.2.1 (novel protein)... 30 5.3
BC125050-1|AAI25051.1| 164|Homo sapiens CG018 protein protein. 30 5.3
AL137247-1|CAI13190.1| 243|Homo sapiens novel protein protein. 30 5.3
AL049788-1|CAB42446.1| 137|Homo sapiens hypothetical protein pr... 30 5.3
AL049786-1|CAB42444.1| 137|Homo sapiens hypothetical protein pr... 30 5.3
AL049785-1|CAB42443.1| 137|Homo sapiens hypothetical protein pr... 30 5.3
BT007420-1|AAP36088.1| 655|Homo sapiens tumor necrosis factor r... 29 7.1
BC021572-1|AAH21572.1| 655|Homo sapiens tumor necrosis factor r... 29 7.1
BC017730-1|AAH17730.1| 655|Homo sapiens tumor necrosis factor r... 29 7.1
BC010241-1|AAH10241.1| 472|Homo sapiens TNFRSF21 protein protein. 29 7.1
AY358304-1|AAQ88671.1| 655|Homo sapiens DR6-TNFR protein. 29 7.1
AL096801-1|CAB75692.1| 655|Homo sapiens tumor necrosis factor r... 29 7.1
AF068868-1|AAC34583.1| 655|Homo sapiens TNFR-related death rece... 29 7.1
>L37418-1|AAB59629.1| 453|Homo sapiens dihydrolipoamide
succinyltransferase protein.
Length = 453
Score = 197 bits (480), Expect = 2e-50
Identities = 94/128 (73%), Positives = 104/128 (81%)
Frame = +2
Query: 116 IAVATPRGLVVPVLRNVESMDYPRIELAMNALAEKARTGNLTPADMQGGTFTISNGGVFG 295
+AVATPRGLVVPV+RNVE+M++ IE + L EKAR L DM GGTFTISNGGVFG
Sbjct: 319 VAVATPRGLVVPVIRNVEAMNFADIERTITELGEKARKNELAIEDMDGGTFTISNGGVFG 378
Query: 296 SLLSMPIINMPQSCILGMHAIFQRPVAIKGKVEIRPMMYLALSYDHRLIDGREAVLFLRK 475
SL PIIN PQS ILGMH IF RPVAI GKVE+RPMMY+AL+YDHRLIDGREAV FLRK
Sbjct: 379 SLFGTPIINPPQSAILGMHGIFDRPVAIGGKVEVRPMMYVALTYDHRLIDGREAVTFLRK 438
Query: 476 VKAGVEDP 499
+KA VEDP
Sbjct: 439 IKAAVEDP 446
>D26535-1|BAA05536.1| 453|Homo sapiens dihydrolipoamide
succinyltransferase protein.
Length = 453
Score = 197 bits (480), Expect = 2e-50
Identities = 94/128 (73%), Positives = 104/128 (81%)
Frame = +2
Query: 116 IAVATPRGLVVPVLRNVESMDYPRIELAMNALAEKARTGNLTPADMQGGTFTISNGGVFG 295
+AVATPRGLVVPV+RNVE+M++ IE + L EKAR L DM GGTFTISNGGVFG
Sbjct: 319 VAVATPRGLVVPVIRNVEAMNFADIERTITELGEKARKNELAIEDMDGGTFTISNGGVFG 378
Query: 296 SLLSMPIINMPQSCILGMHAIFQRPVAIKGKVEIRPMMYLALSYDHRLIDGREAVLFLRK 475
SL PIIN PQS ILGMH IF RPVAI GKVE+RPMMY+AL+YDHRLIDGREAV FLRK
Sbjct: 379 SLFGTPIINPPQSAILGMHGIFDRPVAIGGKVEVRPMMYVALTYDHRLIDGREAVTFLRK 438
Query: 476 VKAGVEDP 499
+KA VEDP
Sbjct: 439 IKAAVEDP 446
>CR456727-1|CAG33008.1| 453|Homo sapiens DLST protein.
Length = 453
Score = 197 bits (480), Expect = 2e-50
Identities = 94/128 (73%), Positives = 104/128 (81%)
Frame = +2
Query: 116 IAVATPRGLVVPVLRNVESMDYPRIELAMNALAEKARTGNLTPADMQGGTFTISNGGVFG 295
+AVATPRGLVVPV+RNVE+M++ IE + L EKAR L DM GGTFTISNGGVFG
Sbjct: 319 VAVATPRGLVVPVIRNVEAMNFADIERTITELGEKARKNELAIEDMDGGTFTISNGGVFG 378
Query: 296 SLLSMPIINMPQSCILGMHAIFQRPVAIKGKVEIRPMMYLALSYDHRLIDGREAVLFLRK 475
SL PIIN PQS ILGMH IF RPVAI GKVE+RPMMY+AL+YDHRLIDGREAV FLRK
Sbjct: 379 SLFGTPIINPPQSAILGMHGIFDRPVAIGGKVEVRPMMYVALTYDHRLIDGREAVTFLRK 438
Query: 476 VKAGVEDP 499
+KA VEDP
Sbjct: 439 IKAAVEDP 446
>BC001922-1|AAH01922.1| 453|Homo sapiens dihydrolipoamide
S-succinyltransferase (E2 component of 2-oxo-glutarate
complex protein.
Length = 453
Score = 197 bits (480), Expect = 2e-50
Identities = 94/128 (73%), Positives = 104/128 (81%)
Frame = +2
Query: 116 IAVATPRGLVVPVLRNVESMDYPRIELAMNALAEKARTGNLTPADMQGGTFTISNGGVFG 295
+AVATPRGLVVPV+RNVE+M++ IE + L EKAR L DM GGTFTISNGGVFG
Sbjct: 319 VAVATPRGLVVPVIRNVEAMNFADIERTITELGEKARKNELAIEDMDGGTFTISNGGVFG 378
Query: 296 SLLSMPIINMPQSCILGMHAIFQRPVAIKGKVEIRPMMYLALSYDHRLIDGREAVLFLRK 475
SL PIIN PQS ILGMH IF RPVAI GKVE+RPMMY+AL+YDHRLIDGREAV FLRK
Sbjct: 379 SLFGTPIINPPQSAILGMHGIFDRPVAIGGKVEVRPMMYVALTYDHRLIDGREAVTFLRK 438
Query: 476 VKAGVEDP 499
+KA VEDP
Sbjct: 439 IKAAVEDP 446
>BC000302-1|AAH00302.1| 453|Homo sapiens dihydrolipoamide
S-succinyltransferase (E2 component of 2-oxo-glutarate
complex protein.
Length = 453
Score = 197 bits (480), Expect = 2e-50
Identities = 94/128 (73%), Positives = 104/128 (81%)
Frame = +2
Query: 116 IAVATPRGLVVPVLRNVESMDYPRIELAMNALAEKARTGNLTPADMQGGTFTISNGGVFG 295
+AVATPRGLVVPV+RNVE+M++ IE + L EKAR L DM GGTFTISNGGVFG
Sbjct: 319 VAVATPRGLVVPVIRNVEAMNFADIERTITELGEKARKNELAIEDMDGGTFTISNGGVFG 378
Query: 296 SLLSMPIINMPQSCILGMHAIFQRPVAIKGKVEIRPMMYLALSYDHRLIDGREAVLFLRK 475
SL PIIN PQS ILGMH IF RPVAI GKVE+RPMMY+AL+YDHRLIDGREAV FLRK
Sbjct: 379 SLFGTPIINPPQSAILGMHGIFDRPVAIGGKVEVRPMMYVALTYDHRLIDGREAVTFLRK 438
Query: 476 VKAGVEDP 499
+KA VEDP
Sbjct: 439 IKAAVEDP 446
>AC006530-2|AAD30181.1| 453|Homo sapiens alpha-KG-E2 protein.
Length = 453
Score = 197 bits (480), Expect = 2e-50
Identities = 94/128 (73%), Positives = 104/128 (81%)
Frame = +2
Query: 116 IAVATPRGLVVPVLRNVESMDYPRIELAMNALAEKARTGNLTPADMQGGTFTISNGGVFG 295
+AVATPRGLVVPV+RNVE+M++ IE + L EKAR L DM GGTFTISNGGVFG
Sbjct: 319 VAVATPRGLVVPVIRNVEAMNFADIERTITELGEKARKNELAIEDMDGGTFTISNGGVFG 378
Query: 296 SLLSMPIINMPQSCILGMHAIFQRPVAIKGKVEIRPMMYLALSYDHRLIDGREAVLFLRK 475
SL PIIN PQS ILGMH IF RPVAI GKVE+RPMMY+AL+YDHRLIDGREAV FLRK
Sbjct: 379 SLFGTPIINPPQSAILGMHGIFDRPVAIGGKVEVRPMMYVALTYDHRLIDGREAVTFLRK 438
Query: 476 VKAGVEDP 499
+KA VEDP
Sbjct: 439 IKAAVEDP 446
>D16373-1|BAA03871.1| 453|Homo sapiens mitochondrial
dihydrolipoamide succinyltransferase protein.
Length = 453
Score = 194 bits (472), Expect = 2e-49
Identities = 93/128 (72%), Positives = 103/128 (80%)
Frame = +2
Query: 116 IAVATPRGLVVPVLRNVESMDYPRIELAMNALAEKARTGNLTPADMQGGTFTISNGGVFG 295
+AVATPRGLVVPV+RNVE+M++ IE + L EKAR L DM GGTFTISNGGVFG
Sbjct: 319 VAVATPRGLVVPVIRNVEAMNFADIERTITELGEKARKNELAIEDMDGGTFTISNGGVFG 378
Query: 296 SLLSMPIINMPQSCILGMHAIFQRPVAIKGKVEIRPMMYLALSYDHRLIDGREAVLFLRK 475
SL IIN PQS ILGMH IF RPVAI GKVE+RPMMY+AL+YDHRLIDGREAV FLRK
Sbjct: 379 SLFGTTIINPPQSAILGMHGIFDRPVAIGGKVEVRPMMYVALTYDHRLIDGREAVTFLRK 438
Query: 476 VKAGVEDP 499
+KA VEDP
Sbjct: 439 IKAAVEDP 446
>S72422-1|AAB31066.1| 451|Homo sapiens alpha-ketoglutarate
dehydrogenase complex dihydrolipoyl succinyltransferase
protein.
Length = 451
Score = 182 bits (444), Expect = 5e-46
Identities = 88/128 (68%), Positives = 101/128 (78%)
Frame = +2
Query: 116 IAVATPRGLVVPVLRNVESMDYPRIELAMNALAEKARTGNLTPADMQGGTFTISNGGVFG 295
+AVATP+GLVVPV+RNVE+M+Y IE + L EKAR DM GGTFTISNGGVFG
Sbjct: 318 VAVATPQGLVVPVIRNVEAMNYADIEQTITELGEKARKNEFAIEDMDGGTFTISNGGVFG 377
Query: 296 SLLSMPIINMPQSCILGMHAIFQRPVAIKGKVEIRPMMYLALSYDHRLIDGREAVLFLRK 475
SL P+ + P S ILGMH IF +PVAI GKVE+RPMMY+AL+YDHRLIDGREAV FLRK
Sbjct: 378 SLFEHPL-STPLSAILGMHGIFDKPVAIGGKVEVRPMMYVALTYDHRLIDGREAVTFLRK 436
Query: 476 VKAGVEDP 499
+KA VEDP
Sbjct: 437 IKAAVEDP 444
>Y00978-1|CAA68787.1| 615|Homo sapiens PDC-E2 precursor (AA -54 to
561) protein.
Length = 615
Score = 91.1 bits (216), Expect = 2e-18
Identities = 51/130 (39%), Positives = 73/130 (56%), Gaps = 2/130 (1%)
Frame = +2
Query: 116 IAVATPRGLVVPVLRNVESMDYPRIELAMNALAEKARTGNLTPADMQGGTFTISNGGVFG 295
+AV+TP GL+ P++ N I + +LA KAR G L P + QGGTFTISN G+FG
Sbjct: 481 VAVSTPAGLITPIVFNAHIKGVETIANDVVSLATKAREGKLQPHEFQGGTFTISNLGMFG 540
Query: 296 SLLSMPIINMPQSCILGMHAIFQR--PVAIKGKVEIRPMMYLALSYDHRLIDGREAVLFL 469
IIN PQ+CIL + A + P + ++ MM + LS DHR++DG +L
Sbjct: 541 IKNFSAIINPPQACILAIGASEDKLVPADNEKGFDVASMMSVTLSCDHRVVDGAVGAQWL 600
Query: 470 RKVKAGVEDP 499
+ + +E P
Sbjct: 601 AEFRKYLEKP 610
>J03866-1|AAA62253.1| 613|Homo sapiens dihydrolipoamide
acetyltransferase protein.
Length = 613
Score = 91.1 bits (216), Expect = 2e-18
Identities = 51/130 (39%), Positives = 73/130 (56%), Gaps = 2/130 (1%)
Frame = +2
Query: 116 IAVATPRGLVVPVLRNVESMDYPRIELAMNALAEKARTGNLTPADMQGGTFTISNGGVFG 295
+AV+TP GL+ P++ N I + +LA KAR G L P + QGGTFTISN G+FG
Sbjct: 479 VAVSTPAGLITPIVFNAHIKGVETIANDVVSLATKAREGKLQPHEFQGGTFTISNLGMFG 538
Query: 296 SLLSMPIINMPQSCILGMHAIFQR--PVAIKGKVEIRPMMYLALSYDHRLIDGREAVLFL 469
IIN PQ+CIL + A + P + ++ MM + LS DHR++DG +L
Sbjct: 539 IKNFSAIINPPQACILAIGASEDKLVPADNEKGFDVASMMSVTLSCDHRVVDGAVGAQWL 598
Query: 470 RKVKAGVEDP 499
+ + +E P
Sbjct: 599 AEFRKYLEKP 608
>BC039084-1|AAH39084.1| 647|Homo sapiens dihydrolipoamide
S-acetyltransferase (E2 component of pyruvate
dehydrogenase co protein.
Length = 647
Score = 91.1 bits (216), Expect = 2e-18
Identities = 51/130 (39%), Positives = 73/130 (56%), Gaps = 2/130 (1%)
Frame = +2
Query: 116 IAVATPRGLVVPVLRNVESMDYPRIELAMNALAEKARTGNLTPADMQGGTFTISNGGVFG 295
+AV+TP GL+ P++ N I + +LA KAR G L P + QGGTFTISN G+FG
Sbjct: 513 VAVSTPAGLITPIVFNAHIKGVETIANDVVSLATKAREGKLQPHEFQGGTFTISNLGMFG 572
Query: 296 SLLSMPIINMPQSCILGMHAIFQR--PVAIKGKVEIRPMMYLALSYDHRLIDGREAVLFL 469
IIN PQ+CIL + A + P + ++ MM + LS DHR++DG +L
Sbjct: 573 IKNFSAIINPPQACILAIGASEDKLVPADNEKGFDVASMMSVTLSCDHRVVDGAVGAQWL 632
Query: 470 RKVKAGVEDP 499
+ + +E P
Sbjct: 633 AEFRKYLEKP 642
>AK223596-1|BAD97316.1| 647|Homo sapiens dihydrolipoamide
S-acetyltransferase (E2 component of pyruvate
dehydrogenase co protein.
Length = 647
Score = 91.1 bits (216), Expect = 2e-18
Identities = 51/130 (39%), Positives = 73/130 (56%), Gaps = 2/130 (1%)
Frame = +2
Query: 116 IAVATPRGLVVPVLRNVESMDYPRIELAMNALAEKARTGNLTPADMQGGTFTISNGGVFG 295
+AV+TP GL+ P++ N I + +LA KAR G L P + QGGTFTISN G+FG
Sbjct: 513 VAVSTPAGLITPIVFNAHIKGVETIANDVVSLATKAREGKLQPHEFQGGTFTISNLGMFG 572
Query: 296 SLLSMPIINMPQSCILGMHAIFQR--PVAIKGKVEIRPMMYLALSYDHRLIDGREAVLFL 469
IIN PQ+CIL + A + P + ++ MM + LS DHR++DG +L
Sbjct: 573 IKNFSAIINPPQACILAIGASEDKLVPADNEKGFDVASMMSVTLSCDHRVVDGAVGAQWL 632
Query: 470 RKVKAGVEDP 499
+ + +E P
Sbjct: 633 AEFRKYLEKP 642
>Y13145-1|CAA73606.1| 501|Homo sapiens protein X protein.
Length = 501
Score = 87.0 bits (206), Expect = 3e-17
Identities = 49/135 (36%), Positives = 79/135 (58%), Gaps = 7/135 (5%)
Frame = +2
Query: 116 IAVATPRGLVVPVLRNVESMDYPRIELAMNALAEKARTGNLTPADMQGGTFTISNGGVFG 295
+AVAT +GL+ P++++ + I ++ AL++KAR G L P + QGG+F+ISN G+FG
Sbjct: 365 VAVATDKGLLTPIIKDAAAKGIQEIADSVKALSKKARDGKLLPEEYQGGSFSISNLGMFG 424
Query: 296 SLLSMPIINMPQSCILGMHAIFQRPVAI-------KGKVEIRPMMYLALSYDHRLIDGRE 454
+IN PQ+CIL + RPV K++ R ++ + +S D R++D
Sbjct: 425 IDEFTAVINPPQACILAVGRF--RPVLKLTEDEEGNAKLQQRQLITVTMSSDSRVVDDEL 482
Query: 455 AVLFLRKVKAGVEDP 499
A FL+ KA +E+P
Sbjct: 483 ATRFLKSFKANLENP 497
>U82328-1|AAC39661.1| 501|Homo sapiens pyruvate dehydrogenase
complex protein X subunit precursor protein.
Length = 501
Score = 87.0 bits (206), Expect = 3e-17
Identities = 49/135 (36%), Positives = 79/135 (58%), Gaps = 7/135 (5%)
Frame = +2
Query: 116 IAVATPRGLVVPVLRNVESMDYPRIELAMNALAEKARTGNLTPADMQGGTFTISNGGVFG 295
+AVAT +GL+ P++++ + I ++ AL++KAR G L P + QGG+F+ISN G+FG
Sbjct: 365 VAVATDKGLLTPIIKDAAAKGIQEIADSVKALSKKARDGKLLPEEYQGGSFSISNLGMFG 424
Query: 296 SLLSMPIINMPQSCILGMHAIFQRPVAI-------KGKVEIRPMMYLALSYDHRLIDGRE 454
+IN PQ+CIL + RPV K++ R ++ + +S D R++D
Sbjct: 425 IDEFTAVINPPQACILAVGRF--RPVLKLTEDEEGNAKLQQRQLITVTMSSDSRVVDDEL 482
Query: 455 AVLFLRKVKAGVEDP 499
A FL+ KA +E+P
Sbjct: 483 ATRFLKSFKANLENP 497
>U79296-1|AAB50223.1| 375|Homo sapiens dihyrolipoamide acetyl
transferase protein.
Length = 375
Score = 87.0 bits (206), Expect = 3e-17
Identities = 49/135 (36%), Positives = 79/135 (58%), Gaps = 7/135 (5%)
Frame = +2
Query: 116 IAVATPRGLVVPVLRNVESMDYPRIELAMNALAEKARTGNLTPADMQGGTFTISNGGVFG 295
+AVAT +GL+ P++++ + I ++ AL++KAR G L P + QGG+F+ISN G+FG
Sbjct: 239 VAVATDKGLLTPIIKDAAAKGIQEIADSVKALSKKARDGKLLPEEYQGGSFSISNLGMFG 298
Query: 296 SLLSMPIINMPQSCILGMHAIFQRPVAI-------KGKVEIRPMMYLALSYDHRLIDGRE 454
+IN PQ+CIL + RPV K++ R ++ + +S D R++D
Sbjct: 299 IDEFTAVINPPQACILAVGRF--RPVLKLTEDEEGNAKLQQRQLITVTMSSDSRVVDDEL 356
Query: 455 AVLFLRKVKAGVEDP 499
A FL+ KA +E+P
Sbjct: 357 ATRFLKSFKANLENP 371
>AJ298105-1|CAC18649.1| 501|Homo sapiens lipoyl-containing
component X protein.
Length = 501
Score = 87.0 bits (206), Expect = 3e-17
Identities = 49/135 (36%), Positives = 79/135 (58%), Gaps = 7/135 (5%)
Frame = +2
Query: 116 IAVATPRGLVVPVLRNVESMDYPRIELAMNALAEKARTGNLTPADMQGGTFTISNGGVFG 295
+AVAT +GL+ P++++ + I ++ AL++KAR G L P + QGG+F+ISN G+FG
Sbjct: 365 VAVATDKGLLTPIIKDAAAKGIQEIADSVKALSKKARDGKLLPEEYQGGSFSISNLGMFG 424
Query: 296 SLLSMPIINMPQSCILGMHAIFQRPVAI-------KGKVEIRPMMYLALSYDHRLIDGRE 454
+IN PQ+CIL + RPV K++ R ++ + +S D R++D
Sbjct: 425 IDEFTAVINPPQACILAVGRF--RPVLKLTEDEEGNAKLQQRQLITVTMSSDSRVVDDEL 482
Query: 455 AVLFLRKVKAGVEDP 499
A FL+ KA +E+P
Sbjct: 483 ATRFLKSFKANLENP 497
>AF001437-1|AAB66315.1| 501|Homo sapiens dihydrolipoamide
dehydrogenase-binding protein protein.
Length = 501
Score = 87.0 bits (206), Expect = 3e-17
Identities = 49/135 (36%), Positives = 79/135 (58%), Gaps = 7/135 (5%)
Frame = +2
Query: 116 IAVATPRGLVVPVLRNVESMDYPRIELAMNALAEKARTGNLTPADMQGGTFTISNGGVFG 295
+AVAT +GL+ P++++ + I ++ AL++KAR G L P + QGG+F+ISN G+FG
Sbjct: 365 VAVATDKGLLTPIIKDAAAKGIQEIADSVKALSKKARDGKLLPEEYQGGSFSISNLGMFG 424
Query: 296 SLLSMPIINMPQSCILGMHAIFQRPVAI-------KGKVEIRPMMYLALSYDHRLIDGRE 454
+IN PQ+CIL + RPV K++ R ++ + +S D R++D
Sbjct: 425 IDEFTAVINPPQACILAVGRF--RPVLKLTEDEEGNAKLQQRQLITVTMSSDSRVVDDEL 482
Query: 455 AVLFLRKVKAGVEDP 499
A FL+ KA +E+P
Sbjct: 483 ATRFLKSFKANLENP 497
>BC010389-1|AAH10389.1| 501|Homo sapiens pyruvate dehydrogenase
complex, component X protein.
Length = 501
Score = 86.6 bits (205), Expect = 4e-17
Identities = 49/135 (36%), Positives = 79/135 (58%), Gaps = 7/135 (5%)
Frame = +2
Query: 116 IAVATPRGLVVPVLRNVESMDYPRIELAMNALAEKARTGNLTPADMQGGTFTISNGGVFG 295
+AVAT +GL+ P++++ + I ++ AL++KAR G L P + QGG+F+ISN G+FG
Sbjct: 365 VAVATVKGLLTPIIKDAAAKGIQEIADSVKALSKKARDGKLLPEEYQGGSFSISNLGMFG 424
Query: 296 SLLSMPIINMPQSCILGMHAIFQRPVAI-------KGKVEIRPMMYLALSYDHRLIDGRE 454
+IN PQ+CIL + RPV K++ R ++ + +S D R++D
Sbjct: 425 IDEFTAVINPPQACILAVGRF--RPVLKLTEDEEGNAKLQQRQLITVTMSSDSRVVDDEL 482
Query: 455 AVLFLRKVKAGVEDP 499
A FL+ KA +E+P
Sbjct: 483 ATRFLKSFKANLENP 497
>X66785-1|CAA47285.1| 482|Homo sapiens transacylase protein.
Length = 482
Score = 74.1 bits (174), Expect = 3e-13
Identities = 45/129 (34%), Positives = 69/129 (53%), Gaps = 1/129 (0%)
Frame = +2
Query: 116 IAVATPRGLVVPVLRNVESMDYPRIELAMNALAEKARTGNLTPADMQGGTFTISNGGVFG 295
IA+ T +GL+VP ++NV+ I +N L + G L+ D+ GGTFT+SN G G
Sbjct: 346 IAMDTEQGLIVPNVKNVQICSIFDIATELNRLQKLGSVGQLSTTDLTGGTFTLSNIGSIG 405
Query: 296 SLLSMPIINMPQSCILGMHAIFQRP-VAIKGKVEIRPMMYLALSYDHRLIDGREAVLFLR 472
+ P+I P+ I + +I P KG+V +M ++ S DHR+IDG F
Sbjct: 406 GTFAKPVIMPPEVAIGALGSIKAIPRFNQKGEVYKAQIMNVSWSADHRVIDGATMSRFSN 465
Query: 473 KVKAGVEDP 499
K+ +E+P
Sbjct: 466 LWKSYLENP 474
>J03208-1|AAA35589.1| 477|Homo sapiens protein ( Human branched
chain acyltransferase mRNA, complete cds. ).
Length = 477
Score = 74.1 bits (174), Expect = 3e-13
Identities = 45/129 (34%), Positives = 69/129 (53%), Gaps = 1/129 (0%)
Frame = +2
Query: 116 IAVATPRGLVVPVLRNVESMDYPRIELAMNALAEKARTGNLTPADMQGGTFTISNGGVFG 295
IA+ T +GL+VP ++NV+ I +N L + G L+ D+ GGTFT+SN G G
Sbjct: 341 IAMDTEQGLIVPNVKNVQICSIFDIATELNRLQKLGSVGQLSTTDLTGGTFTLSNIGSIG 400
Query: 296 SLLSMPIINMPQSCILGMHAIFQRP-VAIKGKVEIRPMMYLALSYDHRLIDGREAVLFLR 472
+ P+I P+ I + +I P KG+V +M ++ S DHR+IDG F
Sbjct: 401 GTFAKPVIMPPEVAIGALGSIKAIPRFNQKGEVYKAQIMNVSWSADHRVIDGATMSRFSN 460
Query: 473 KVKAGVEDP 499
K+ +E+P
Sbjct: 461 LWKSYLENP 469
>BT007372-1|AAP36036.1| 482|Homo sapiens dihydrolipoamide branched
chain transacylase (E2 component of branched chain ke
protein.
Length = 482
Score = 74.1 bits (174), Expect = 3e-13
Identities = 45/129 (34%), Positives = 69/129 (53%), Gaps = 1/129 (0%)
Frame = +2
Query: 116 IAVATPRGLVVPVLRNVESMDYPRIELAMNALAEKARTGNLTPADMQGGTFTISNGGVFG 295
IA+ T +GL+VP ++NV+ I +N L + G L+ D+ GGTFT+SN G G
Sbjct: 346 IAMDTEQGLIVPNVKNVQICSIFDIATELNRLQKLGSVGQLSTTDLTGGTFTLSNIGSIG 405
Query: 296 SLLSMPIINMPQSCILGMHAIFQRP-VAIKGKVEIRPMMYLALSYDHRLIDGREAVLFLR 472
+ P+I P+ I + +I P KG+V +M ++ S DHR+IDG F
Sbjct: 406 GTFAKPVIMPPEVAIGALGSIKAIPRFNQKGEVYKAQIMNVSWSADHRVIDGATMSRFSN 465
Query: 473 KVKAGVEDP 499
K+ +E+P
Sbjct: 466 LWKSYLENP 474
>BC016675-1|AAH16675.1| 482|Homo sapiens dihydrolipoamide branched
chain transacylase E2 protein.
Length = 482
Score = 74.1 bits (174), Expect = 3e-13
Identities = 45/129 (34%), Positives = 69/129 (53%), Gaps = 1/129 (0%)
Frame = +2
Query: 116 IAVATPRGLVVPVLRNVESMDYPRIELAMNALAEKARTGNLTPADMQGGTFTISNGGVFG 295
IA+ T +GL+VP ++NV+ I +N L + G L+ D+ GGTFT+SN G G
Sbjct: 346 IAMDTEQGLIVPNVKNVQICSIFDIATELNRLQKLGSVGQLSTTDLTGGTFTLSNIGSIG 405
Query: 296 SLLSMPIINMPQSCILGMHAIFQRP-VAIKGKVEIRPMMYLALSYDHRLIDGREAVLFLR 472
+ P+I P+ I + +I P KG+V +M ++ S DHR+IDG F
Sbjct: 406 GTFAKPVIMPPEVAIGALGSIKAIPRFNQKGEVYKAQIMNVSWSADHRVIDGATMSRFSN 465
Query: 473 KVKAGVEDP 499
K+ +E+P
Sbjct: 466 LWKSYLENP 474
>M27093-1|AAA64512.1| 477|Homo sapiens dihydrolipoyl transacylase
protein.
Length = 477
Score = 72.9 bits (171), Expect = 6e-13
Identities = 44/129 (34%), Positives = 69/129 (53%), Gaps = 1/129 (0%)
Frame = +2
Query: 116 IAVATPRGLVVPVLRNVESMDYPRIELAMNALAEKARTGNLTPADMQGGTFTISNGGVFG 295
IA+ T +G++VP ++NV+ I +N L + G L+ D+ GGTFT+SN G G
Sbjct: 341 IAMDTEQGVIVPNVKNVQICSIFDIATELNRLQKLGSVGQLSTTDLTGGTFTLSNIGSIG 400
Query: 296 SLLSMPIINMPQSCILGMHAIFQRP-VAIKGKVEIRPMMYLALSYDHRLIDGREAVLFLR 472
+ P+I P+ I + +I P KG+V +M ++ S DHR+IDG F
Sbjct: 401 GTFAKPVIMPPEVAIGALGSIKAIPRFNQKGEVYKAQIMNVSWSADHRVIDGATMSRFSN 460
Query: 473 KVKAGVEDP 499
K+ +E+P
Sbjct: 461 LWKSYLENP 469
>AL445928-9|CAH72257.1| 482|Homo sapiens dihydrolipoamide branched
chain transacylase E2 protein.
Length = 482
Score = 71.7 bits (168), Expect = 1e-12
Identities = 44/129 (34%), Positives = 68/129 (52%), Gaps = 1/129 (0%)
Frame = +2
Query: 116 IAVATPRGLVVPVLRNVESMDYPRIELAMNALAEKARTGNLTPADMQGGTFTISNGGVFG 295
IA+ T +GL+VP ++NV+ I +N L + L+ D+ GGTFT+SN G G
Sbjct: 346 IAMDTEQGLIVPNVKNVQICSIFDIATELNRLQKLGSVSQLSTTDLTGGTFTLSNIGSIG 405
Query: 296 SLLSMPIINMPQSCILGMHAIFQRP-VAIKGKVEIRPMMYLALSYDHRLIDGREAVLFLR 472
+ P+I P+ I + +I P KG+V +M ++ S DHR+IDG F
Sbjct: 406 GTFAKPVIMPPEVAIGALGSIKAIPRFNQKGEVYKAQIMNVSWSADHRVIDGATMSRFSN 465
Query: 473 KVKAGVEDP 499
K+ +E+P
Sbjct: 466 LWKSYLENP 474
>X13822-1|CAA32052.1| 220|Homo sapiens dihydrolipoamide
S-acetyltransferase protein.
Length = 220
Score = 34.7 bits (76), Expect = 0.19
Identities = 17/43 (39%), Positives = 24/43 (55%)
Frame = +2
Query: 116 IAVATPRGLVVPVLRNVESMDYPRIELAMNALAEKARTGNLTP 244
+AV+TP GL+ P++ N I + +LA KAR G L P
Sbjct: 177 VAVSTPAGLITPIVFNAHIKGVETIANDVVSLATKAREGKLQP 219
>Z73359-2|CAC94789.1| 137|Homo sapiens 92M18.2.1 (novel protein)
protein.
Length = 137
Score = 29.9 bits (64), Expect = 5.3
Identities = 26/92 (28%), Positives = 38/92 (41%), Gaps = 4/92 (4%)
Frame = +1
Query: 229 W*FNTSGHARRNVHNKQWRRIRLVVIYANHKHAAILHSGNARYLPTTRRYQGQGRNKTDD 408
W FN ARRN+H +I + ++H HS P +R + Q RN
Sbjct: 43 WKFNVQELARRNIHGVSREKIHR--MKERYEHDVTFHSVLHAEKP-SRMNRNQDRNNALP 99
Query: 409 VSSALIRPQI----NRRSRGGVVSKESQSWRG 492
++A NRR+ GG ++ S RG
Sbjct: 100 SNNARYWNSYTEFPNRRAHGGFTNESSYHRRG 131
>BC125050-1|AAI25051.1| 164|Homo sapiens CG018 protein protein.
Length = 164
Score = 29.9 bits (64), Expect = 5.3
Identities = 26/92 (28%), Positives = 38/92 (41%), Gaps = 4/92 (4%)
Frame = +1
Query: 229 W*FNTSGHARRNVHNKQWRRIRLVVIYANHKHAAILHSGNARYLPTTRRYQGQGRNKTDD 408
W FN ARRN+H +I + ++H HS P +R + Q RN
Sbjct: 70 WKFNVQELARRNIHGVSREKIHR--MKERYEHDVTFHSVLHAEKP-SRMNRNQDRNNALP 126
Query: 409 VSSALIRPQI----NRRSRGGVVSKESQSWRG 492
++A NRR+ GG ++ S RG
Sbjct: 127 SNNARYWNSYTEFPNRRAHGGFTNESSYHRRG 158
>AL137247-1|CAI13190.1| 243|Homo sapiens novel protein protein.
Length = 243
Score = 29.9 bits (64), Expect = 5.3
Identities = 26/92 (28%), Positives = 38/92 (41%), Gaps = 4/92 (4%)
Frame = +1
Query: 229 W*FNTSGHARRNVHNKQWRRIRLVVIYANHKHAAILHSGNARYLPTTRRYQGQGRNKTDD 408
W FN ARRN+H +I + ++H HS P +R + Q RN
Sbjct: 149 WKFNVQELARRNIHGVSREKIHR--MKERYEHDVTFHSVLHAEKP-SRMNRNQDRNNALP 205
Query: 409 VSSALIRPQI----NRRSRGGVVSKESQSWRG 492
++A NRR+ GG ++ S RG
Sbjct: 206 SNNARYWNSYTEFPNRRAHGGFTNESSYHRRG 237
>AL049788-1|CAB42446.1| 137|Homo sapiens hypothetical protein
protein.
Length = 137
Score = 29.9 bits (64), Expect = 5.3
Identities = 26/92 (28%), Positives = 38/92 (41%), Gaps = 4/92 (4%)
Frame = +1
Query: 229 W*FNTSGHARRNVHNKQWRRIRLVVIYANHKHAAILHSGNARYLPTTRRYQGQGRNKTDD 408
W FN ARRN+H +I + ++H HS P +R + Q RN
Sbjct: 43 WKFNVQELARRNIHGVSREKIHR--MKERYEHDVTFHSVLHAEKP-SRMNRNQDRNNALP 99
Query: 409 VSSALIRPQI----NRRSRGGVVSKESQSWRG 492
++A NRR+ GG ++ S RG
Sbjct: 100 SNNARYWNSYTEFPNRRAHGGFTNESSYHRRG 131
>AL049786-1|CAB42444.1| 137|Homo sapiens hypothetical protein
protein.
Length = 137
Score = 29.9 bits (64), Expect = 5.3
Identities = 26/92 (28%), Positives = 38/92 (41%), Gaps = 4/92 (4%)
Frame = +1
Query: 229 W*FNTSGHARRNVHNKQWRRIRLVVIYANHKHAAILHSGNARYLPTTRRYQGQGRNKTDD 408
W FN ARRN+H +I + ++H HS P +R + Q RN
Sbjct: 43 WKFNVQELARRNIHGVSREKIHR--MKERYEHDVTFHSVLHAEKP-SRMNRNQDRNNALP 99
Query: 409 VSSALIRPQI----NRRSRGGVVSKESQSWRG 492
++A NRR+ GG ++ S RG
Sbjct: 100 SNNARYWNSYTEFPNRRAHGGFTNESSYHRRG 131
>AL049785-1|CAB42443.1| 137|Homo sapiens hypothetical protein
protein.
Length = 137
Score = 29.9 bits (64), Expect = 5.3
Identities = 26/92 (28%), Positives = 38/92 (41%), Gaps = 4/92 (4%)
Frame = +1
Query: 229 W*FNTSGHARRNVHNKQWRRIRLVVIYANHKHAAILHSGNARYLPTTRRYQGQGRNKTDD 408
W FN ARRN+H +I + ++H HS P +R + Q RN
Sbjct: 43 WKFNVQELARRNIHGVSREKIHR--MKERYEHDVTFHSVLHAEKP-SRMNRNQDRNNALP 99
Query: 409 VSSALIRPQI----NRRSRGGVVSKESQSWRG 492
++A NRR+ GG ++ S RG
Sbjct: 100 SNNARYWNSYTEFPNRRAHGGFTNESSYHRRG 131
>BT007420-1|AAP36088.1| 655|Homo sapiens tumor necrosis factor
receptor superfamily, member 21 protein.
Length = 655
Score = 29.5 bits (63), Expect = 7.1
Identities = 14/40 (35%), Positives = 22/40 (55%)
Frame = +1
Query: 376 YQGQGRNKTDDVSSALIRPQINRRSRGGVVSKESQSWRGR 495
Y +G N T+ SSA +RP++ + G V + S RG+
Sbjct: 246 YVPKGMNSTESNSSASVRPKVLSSIQEGTVPDNTSSARGK 285
>BC021572-1|AAH21572.1| 655|Homo sapiens tumor necrosis factor
receptor superfamily, member 21 protein.
Length = 655
Score = 29.5 bits (63), Expect = 7.1
Identities = 14/40 (35%), Positives = 22/40 (55%)
Frame = +1
Query: 376 YQGQGRNKTDDVSSALIRPQINRRSRGGVVSKESQSWRGR 495
Y +G N T+ SSA +RP++ + G V + S RG+
Sbjct: 246 YVPKGMNSTESNSSASVRPKVLSSIQEGTVPDNTSSARGK 285
>BC017730-1|AAH17730.1| 655|Homo sapiens tumor necrosis factor
receptor superfamily, member 21 protein.
Length = 655
Score = 29.5 bits (63), Expect = 7.1
Identities = 14/40 (35%), Positives = 22/40 (55%)
Frame = +1
Query: 376 YQGQGRNKTDDVSSALIRPQINRRSRGGVVSKESQSWRGR 495
Y +G N T+ SSA +RP++ + G V + S RG+
Sbjct: 246 YVPKGMNSTESNSSASVRPKVLSSIQEGTVPDNTSSARGK 285
>BC010241-1|AAH10241.1| 472|Homo sapiens TNFRSF21 protein protein.
Length = 472
Score = 29.5 bits (63), Expect = 7.1
Identities = 14/40 (35%), Positives = 22/40 (55%)
Frame = +1
Query: 376 YQGQGRNKTDDVSSALIRPQINRRSRGGVVSKESQSWRGR 495
Y +G N T+ SSA +RP++ + G V + S RG+
Sbjct: 63 YVPKGMNSTESNSSASVRPKVLSSIQEGTVPDNTSSARGK 102
>AY358304-1|AAQ88671.1| 655|Homo sapiens DR6-TNFR protein.
Length = 655
Score = 29.5 bits (63), Expect = 7.1
Identities = 14/40 (35%), Positives = 22/40 (55%)
Frame = +1
Query: 376 YQGQGRNKTDDVSSALIRPQINRRSRGGVVSKESQSWRGR 495
Y +G N T+ SSA +RP++ + G V + S RG+
Sbjct: 246 YVPKGMNSTESNSSASVRPKVLSSIQEGTVPDNTSSARGK 285
>AL096801-1|CAB75692.1| 655|Homo sapiens tumor necrosis factor
receptor superfamily, member 21 protein.
Length = 655
Score = 29.5 bits (63), Expect = 7.1
Identities = 14/40 (35%), Positives = 22/40 (55%)
Frame = +1
Query: 376 YQGQGRNKTDDVSSALIRPQINRRSRGGVVSKESQSWRGR 495
Y +G N T+ SSA +RP++ + G V + S RG+
Sbjct: 246 YVPKGMNSTESNSSASVRPKVLSSIQEGTVPDNTSSARGK 285
>AF068868-1|AAC34583.1| 655|Homo sapiens TNFR-related death
receptor-6 protein.
Length = 655
Score = 29.5 bits (63), Expect = 7.1
Identities = 14/40 (35%), Positives = 22/40 (55%)
Frame = +1
Query: 376 YQGQGRNKTDDVSSALIRPQINRRSRGGVVSKESQSWRGR 495
Y +G N T+ SSA +RP++ + G V + S RG+
Sbjct: 246 YVPKGMNSTESNSSASVRPKVLSSIQEGTVPDNTSSARGK 285
Database: human
Posted date: Oct 23, 2007 1:18 PM
Number of letters in database: 76,859,062
Number of sequences in database: 237,096
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 75,320,929
Number of Sequences: 237096
Number of extensions: 1633213
Number of successful extensions: 7620
Number of sequences better than 10.0: 38
Number of HSP's better than 10.0 without gapping: 7483
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 7602
length of database: 76,859,062
effective HSP length: 85
effective length of database: 56,705,902
effective search space used: 4706589866
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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