Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= I10A02NGRL0003_P21
(586 letters)
Database: uniref50
1,657,284 sequences; 575,637,011 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
UniRef50_Q9Y020 Cluster: 3-dehydroecdysone 3beta-reductase precu... 56 6e-07
UniRef50_Q5BKE9 Cluster: LOC594893 protein; n=5; Xenopus tropica... 46 5e-04
UniRef50_Q9U2J5 Cluster: Putative uncharacterized protein; n=2; ... 44 0.004
UniRef50_Q9VHX4 Cluster: CG2767-PA; n=4; Endopterygota|Rep: CG27... 43 0.006
UniRef50_P51857 Cluster: 3-oxo-5-beta-steroid 4-dehydrogenase (E... 42 0.014
UniRef50_Q17DN0 Cluster: Aldo-keto reductase; n=5; Culicidae|Rep... 40 0.033
UniRef50_A5KSS3 Cluster: Aldehyde reductase; n=1; candidate divi... 40 0.043
UniRef50_Q5T2L2 Cluster: Aldo-keto reductase family 1 member C-l... 38 0.13
UniRef50_Q0VGY1 Cluster: 3-alpha-hydroxysteroid dehydrogenase; n... 38 0.17
UniRef50_Q17DN1 Cluster: Aldo-keto reductase; n=1; Aedes aegypti... 38 0.17
UniRef50_UPI0000E4A7CE Cluster: PREDICTED: similar to LOC553452 ... 38 0.23
UniRef50_Q7QK25 Cluster: ENSANGP00000019775; n=2; Anopheles gamb... 37 0.30
UniRef50_Q55FL3 Cluster: Aldo-keto reductase; n=2; Dictyostelium... 37 0.40
UniRef50_UPI00006CD296 Cluster: oxidoreductase, aldo/keto reduct... 36 0.70
UniRef50_UPI0000D56CE5 Cluster: PREDICTED: similar to CG6084-PA,... 36 0.93
UniRef50_Q9NAI5 Cluster: Putative uncharacterized protein; n=3; ... 35 1.2
UniRef50_Q4Q5N9 Cluster: Prostaglandin f synthase, putative; n=7... 34 2.2
UniRef50_UPI00015B56A3 Cluster: PREDICTED: similar to aldo-keto ... 34 2.8
UniRef50_UPI0000499260 Cluster: hypothetical protein 397.t00010;... 33 3.8
UniRef50_Q9VTL0 Cluster: CG6083-PA; n=4; Diptera|Rep: CG6083-PA ... 33 5.0
UniRef50_Q5UQY8 Cluster: Putative ankyrin repeat protein L897; n... 33 5.0
UniRef50_A6LZ55 Cluster: 2,5-didehydrogluconate reductase; n=1; ... 32 8.7
UniRef50_Q5CUH7 Cluster: Cullin domain containing protein; n=2; ... 32 8.7
>UniRef50_Q9Y020 Cluster: 3-dehydroecdysone 3beta-reductase
precursor; n=1; Spodoptera littoralis|Rep:
3-dehydroecdysone 3beta-reductase precursor - Spodoptera
littoralis (Egyptian cotton leafworm)
Length = 345
Score = 56.0 bits (129), Expect = 6e-07
Identities = 21/42 (50%), Positives = 30/42 (71%)
Frame = +3
Query: 6 QNIDIIDFNLTREEVAKLSQFNSNYRLRTPAKWYPHPYFPFE 131
+NI+I DF L EE+ K++QFNSN R P+ W HP++PF+
Sbjct: 288 ENINIFDFKLKEEEIEKINQFNSNTRYTLPSFWQKHPFYPFD 329
>UniRef50_Q5BKE9 Cluster: LOC594893 protein; n=5; Xenopus
tropicalis|Rep: LOC594893 protein - Xenopus tropicalis
(Western clawed frog) (Silurana tropicalis)
Length = 345
Score = 46.4 bits (105), Expect = 5e-04
Identities = 17/45 (37%), Positives = 29/45 (64%)
Frame = +3
Query: 3 KQNIDIIDFNLTREEVAKLSQFNSNYRLRTPAKWYPHPYFPFEKK 137
KQN+++ DF L++EE+A + N N R + ++W HP +PF +
Sbjct: 300 KQNLEVFDFQLSQEEMAAIDGLNKNMRYWSFSEWEKHPQYPFHSQ 344
>UniRef50_Q9U2J5 Cluster: Putative uncharacterized protein; n=2;
Caenorhabditis|Rep: Putative uncharacterized protein -
Caenorhabditis elegans
Length = 339
Score = 43.6 bits (98), Expect = 0.004
Identities = 18/43 (41%), Positives = 28/43 (65%), Gaps = 1/43 (2%)
Frame = +3
Query: 3 KQNIDIIDFNLTREEVAKLSQFNSNYRLRTPAKW-YPHPYFPF 128
+QNI+I F LT +E+A++ N ++R+ P Y HPYFP+
Sbjct: 277 RQNINIFKFRLTSQEIARIKALNIDFRILNPLLGNYDHPYFPW 319
>UniRef50_Q9VHX4 Cluster: CG2767-PA; n=4; Endopterygota|Rep:
CG2767-PA - Drosophila melanogaster (Fruit fly)
Length = 329
Score = 42.7 bits (96), Expect = 0.006
Identities = 22/48 (45%), Positives = 30/48 (62%), Gaps = 3/48 (6%)
Frame = +3
Query: 3 KQNIDIIDFNLTREEVAKLSQFNSNYRLRTPAKWY---PHPYFPFEKK 137
KQN+D+ DF LT EEVAKLS + N R+ A ++ HP F F+ +
Sbjct: 279 KQNLDVFDFELTAEEVAKLSSLDQNIRICDFAFFHGVERHPEFTFKNQ 326
>UniRef50_P51857 Cluster: 3-oxo-5-beta-steroid 4-dehydrogenase (EC
1.3.1.3) (Delta(4)-3- ketosteroid 5-beta-reductase);
n=124; cellular organisms|Rep: 3-oxo-5-beta-steroid
4-dehydrogenase (EC 1.3.1.3) (Delta(4)-3- ketosteroid
5-beta-reductase) - Homo sapiens (Human)
Length = 326
Score = 41.5 bits (93), Expect = 0.014
Identities = 17/42 (40%), Positives = 22/42 (52%)
Frame = +3
Query: 3 KQNIDIIDFNLTREEVAKLSQFNSNYRLRTPAKWYPHPYFPF 128
K+N I DF+LT EE+ + N N R W HP +PF
Sbjct: 281 KENFQIFDFSLTEEEMKDIEALNKNVRFVELLMWRDHPEYPF 322
>UniRef50_Q17DN0 Cluster: Aldo-keto reductase; n=5; Culicidae|Rep:
Aldo-keto reductase - Aedes aegypti (Yellowfever
mosquito)
Length = 324
Score = 40.3 bits (90), Expect = 0.033
Identities = 17/42 (40%), Positives = 27/42 (64%)
Frame = +3
Query: 3 KQNIDIIDFNLTREEVAKLSQFNSNYRLRTPAKWYPHPYFPF 128
KQN++I DF L+ +++A L FN+N R+ + H Y+PF
Sbjct: 279 KQNLEIFDFELSSDDMAILDGFNTNQRMVRLSLLKEHKYYPF 320
>UniRef50_A5KSS3 Cluster: Aldehyde reductase; n=1; candidate
division TM7 genomosp. GTL1|Rep: Aldehyde reductase -
candidate division TM7 genomosp. GTL1
Length = 299
Score = 39.9 bits (89), Expect = 0.043
Identities = 16/40 (40%), Positives = 23/40 (57%)
Frame = +3
Query: 3 KQNIDIIDFNLTREEVAKLSQFNSNYRLRTPAKWYPHPYF 122
K+N +I F L+ E +A L+ N N R P +W+ PYF
Sbjct: 260 KENFEIATFELSNEHMAALNTLNRNKRFVNPIEWWGFPYF 299
>UniRef50_Q5T2L2 Cluster: Aldo-keto reductase family 1 member C-like
protein 1; n=14; Eutheria|Rep: Aldo-keto reductase
family 1 member C-like protein 1 - Homo sapiens (Human)
Length = 302
Score = 38.3 bits (85), Expect = 0.13
Identities = 18/45 (40%), Positives = 24/45 (53%)
Frame = +3
Query: 3 KQNIDIIDFNLTREEVAKLSQFNSNYRLRTPAKWYPHPYFPFEKK 137
K+N I DF LT E++ + N N R A HPYFPF ++
Sbjct: 260 KENFQIFDFELTPEDMKAIDGLNRNLRYDNAAN---HPYFPFSEE 301
>UniRef50_Q0VGY1 Cluster: 3-alpha-hydroxysteroid dehydrogenase;
n=13; Tetrapoda|Rep: 3-alpha-hydroxysteroid
dehydrogenase - Xenopus tropicalis (Western clawed frog)
(Silurana tropicalis)
Length = 324
Score = 37.9 bits (84), Expect = 0.17
Identities = 13/45 (28%), Positives = 24/45 (53%)
Frame = +3
Query: 3 KQNIDIIDFNLTREEVAKLSQFNSNYRLRTPAKWYPHPYFPFEKK 137
+QN + DF L E++ + N N R ++W HP +P+ ++
Sbjct: 279 QQNFQVFDFQLDAEDMRSIDGLNRNMRYIDTSRWSDHPKYPYSEE 323
>UniRef50_Q17DN1 Cluster: Aldo-keto reductase; n=1; Aedes
aegypti|Rep: Aldo-keto reductase - Aedes aegypti
(Yellowfever mosquito)
Length = 284
Score = 37.9 bits (84), Expect = 0.17
Identities = 18/42 (42%), Positives = 23/42 (54%)
Frame = +3
Query: 3 KQNIDIIDFNLTREEVAKLSQFNSNYRLRTPAKWYPHPYFPF 128
+QNIDI DF LT EE+ + F++ R H YFPF
Sbjct: 239 RQNIDIFDFKLTEEEIKIMDGFHTGQRTVPFNLCTSHKYFPF 280
>UniRef50_UPI0000E4A7CE Cluster: PREDICTED: similar to LOC553452
protein; n=6; Strongylocentrotus purpuratus|Rep:
PREDICTED: similar to LOC553452 protein -
Strongylocentrotus purpuratus
Length = 321
Score = 37.5 bits (83), Expect = 0.23
Identities = 17/46 (36%), Positives = 24/46 (52%)
Frame = +3
Query: 3 KQNIDIIDFNLTREEVAKLSQFNSNYRLRTPAKWYPHPYFPFEKKN 140
+QN + ++F L++EE L N NYRL A Y+PF N
Sbjct: 276 QQNFEALNFELSKEEFQALVNLNKNYRLLNFAPMKNMKYYPFNDNN 321
>UniRef50_Q7QK25 Cluster: ENSANGP00000019775; n=2; Anopheles gambiae
str. PEST|Rep: ENSANGP00000019775 - Anopheles gambiae
str. PEST
Length = 319
Score = 37.1 bits (82), Expect = 0.30
Identities = 19/44 (43%), Positives = 27/44 (61%), Gaps = 1/44 (2%)
Frame = +3
Query: 3 KQNIDIIDFNLTREEVAKLSQFNSNYRLR-TPAKWYPHPYFPFE 131
+QNID+ DF LT EE+ L+ F+S + P K H Y+PF+
Sbjct: 275 RQNIDVCDFKLTGEEIEYLASFHSARTIPFLPLK--SHKYYPFD 316
>UniRef50_Q55FL3 Cluster: Aldo-keto reductase; n=2; Dictyostelium
discoideum AX4|Rep: Aldo-keto reductase - Dictyostelium
discoideum AX4
Length = 321
Score = 36.7 bits (81), Expect = 0.40
Identities = 12/42 (28%), Positives = 27/42 (64%)
Frame = +3
Query: 6 QNIDIIDFNLTREEVAKLSQFNSNYRLRTPAKWYPHPYFPFE 131
+N +I DF L+ +++ K++ N+N R +P ++ P++ F+
Sbjct: 280 ENFNIFDFQLSNDDIEKINSLNANIRTCSPITFFGTPFYLFD 321
>UniRef50_UPI00006CD296 Cluster: oxidoreductase, aldo/keto reductase
family protein; n=1; Tetrahymena thermophila SB210|Rep:
oxidoreductase, aldo/keto reductase family protein -
Tetrahymena thermophila SB210
Length = 295
Score = 35.9 bits (79), Expect = 0.70
Identities = 17/43 (39%), Positives = 26/43 (60%), Gaps = 3/43 (6%)
Frame = +3
Query: 3 KQNIDIIDFNLTREEVAKLSQFNSNYRLRTP--AKWYPH-PYF 122
++NI+ DF+L ++AKL N N+RL P +W+ PYF
Sbjct: 252 RENIESTDFSLDEADIAKLKGLNKNFRLIDPYDREWWKRVPYF 294
>UniRef50_UPI0000D56CE5 Cluster: PREDICTED: similar to CG6084-PA,
isoform A; n=1; Tribolium castaneum|Rep: PREDICTED:
similar to CG6084-PA, isoform A - Tribolium castaneum
Length = 493
Score = 35.5 bits (78), Expect = 0.93
Identities = 13/42 (30%), Positives = 26/42 (61%)
Frame = +3
Query: 6 QNIDIIDFNLTREEVAKLSQFNSNYRLRTPAKWYPHPYFPFE 131
+N+ I DF L+ +++ + F+ N R+ A+ HP++PF+
Sbjct: 447 ENMSIFDFTLSEDDMKYIGTFDCNGRICPQAEAREHPFYPFK 488
>UniRef50_Q9NAI5 Cluster: Putative uncharacterized protein; n=3;
Caenorhabditis|Rep: Putative uncharacterized protein -
Caenorhabditis elegans
Length = 316
Score = 35.1 bits (77), Expect = 1.2
Identities = 15/42 (35%), Positives = 25/42 (59%), Gaps = 1/42 (2%)
Frame = +3
Query: 6 QNIDIIDFNLTREEVAKLSQFNSNYRL-RTPAKWYPHPYFPF 128
+N+ + DF LT EE++K+ N N+R+ + HP+ PF
Sbjct: 271 ENLAVFDFQLTAEEISKIDGINKNWRIVDLSQRDGDHPHCPF 312
>UniRef50_Q4Q5N9 Cluster: Prostaglandin f synthase, putative; n=7;
cellular organisms|Rep: Prostaglandin f synthase,
putative - Leishmania major
Length = 279
Score = 34.3 bits (75), Expect = 2.2
Identities = 15/45 (33%), Positives = 26/45 (57%)
Frame = +3
Query: 3 KQNIDIIDFNLTREEVAKLSQFNSNYRLRTPAKWYPHPYFPFEKK 137
KQN D+ DF L+ E++ ++ + N R+ + P +FP E+K
Sbjct: 239 KQNFDVFDFELSPEDMRRIESMDRNSRIGSS----PETFFPTERK 279
>UniRef50_UPI00015B56A3 Cluster: PREDICTED: similar to aldo-keto
reductase; n=1; Nasonia vitripennis|Rep: PREDICTED:
similar to aldo-keto reductase - Nasonia vitripennis
Length = 321
Score = 33.9 bits (74), Expect = 2.8
Identities = 15/42 (35%), Positives = 24/42 (57%)
Frame = +3
Query: 3 KQNIDIIDFNLTREEVAKLSQFNSNYRLRTPAKWYPHPYFPF 128
K+NIDI DF LT EE+A + + + +R + + +PF
Sbjct: 276 KENIDIFDFKLTPEEIAAIDKLDCGFRTCSAIEHKDCKEYPF 317
>UniRef50_UPI0000499260 Cluster: hypothetical protein 397.t00010;
n=3; Entamoeba histolytica HM-1:IMSS|Rep: hypothetical
protein 397.t00010 - Entamoeba histolytica HM-1:IMSS
Length = 517
Score = 33.5 bits (73), Expect = 3.8
Identities = 20/58 (34%), Positives = 31/58 (53%)
Frame = -3
Query: 353 IMNTYLYEFGMKIKCFRKHFSSD*LLYTKINSNNKDTFCLIKILIKCLTADCGILILF 180
I N YL F ++IK F ++F S LL+ I ++ +CL L K L + I++ F
Sbjct: 408 IKNKYLISFYLEIKLFLRYFLSPLLLFNLIKNDPYQYYCL---LYKILNTEAVIVLPF 462
>UniRef50_Q9VTL0 Cluster: CG6083-PA; n=4; Diptera|Rep: CG6083-PA -
Drosophila melanogaster (Fruit fly)
Length = 322
Score = 33.1 bits (72), Expect = 5.0
Identities = 14/40 (35%), Positives = 22/40 (55%)
Frame = +3
Query: 18 IIDFNLTREEVAKLSQFNSNYRLRTPAKWYPHPYFPFEKK 137
I DF L +++ +++ + N R T Y HP+ PFE K
Sbjct: 278 IWDFELAVDDIQAINELDCNGRFMTMKAAYGHPHHPFEPK 317
>UniRef50_Q5UQY8 Cluster: Putative ankyrin repeat protein L897; n=1;
Acanthamoeba polyphaga mimivirus|Rep: Putative ankyrin
repeat protein L897 - Mimivirus
Length = 322
Score = 33.1 bits (72), Expect = 5.0
Identities = 18/46 (39%), Positives = 26/46 (56%)
Frame = +1
Query: 214 HLIKILIRQNVSLLFEFIFVYNN*SEEKCLRKHFIFIPNSYKYVFI 351
H++KI R+N+ + E+ NN K L K FIF N Y+ +FI
Sbjct: 173 HVVKIT-RENIIDVIEYAVQINNCDIIKILVKKFIFWANDYRKIFI 217
>UniRef50_A6LZ55 Cluster: 2,5-didehydrogluconate reductase; n=1;
Clostridium beijerinckii NCIMB 8052|Rep:
2,5-didehydrogluconate reductase - Clostridium
beijerinckii NCIMB 8052
Length = 289
Score = 32.3 bits (70), Expect = 8.7
Identities = 14/41 (34%), Positives = 25/41 (60%), Gaps = 1/41 (2%)
Frame = +3
Query: 3 KQNIDIIDFNLTREEVAKLSQFNSNYRL-RTPAKWYPHPYF 122
K+NI + DF L+ EE+ K++Q N+ R +P + +P +
Sbjct: 240 KENIQLFDFELSSEEMEKINQLNTGKRYSHSPTGYMINPLY 280
>UniRef50_Q5CUH7 Cluster: Cullin domain containing protein; n=2;
Cryptosporidium|Rep: Cullin domain containing protein -
Cryptosporidium parvum Iowa II
Length = 851
Score = 32.3 bits (70), Expect = 8.7
Identities = 14/40 (35%), Positives = 20/40 (50%)
Frame = +3
Query: 21 IDFNLTREEVAKLSQFNSNYRLRTPAKWYPHPYFPFEKKN 140
++F E++ LS NY++ TP W HPY F N
Sbjct: 549 MEFQQINNEISVLSNTIINYKVITPNFWITHPYINFSFLN 588
Database: uniref50
Posted date: Oct 5, 2007 11:19 AM
Number of letters in database: 575,637,011
Number of sequences in database: 1,657,284
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 497,442,285
Number of Sequences: 1657284
Number of extensions: 9334568
Number of successful extensions: 18163
Number of sequences better than 10.0: 23
Number of HSP's better than 10.0 without gapping: 17636
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 18155
length of database: 575,637,011
effective HSP length: 96
effective length of database: 416,537,747
effective search space used: 40820699206
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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