Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= I10A02NGRL0003_N17
(348 letters)
Database: human
237,096 sequences; 76,859,062 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
M23294-1|AAA52645.1| 556|Homo sapiens beta-hexosaminidase beta-... 91 1e-18
M19735-1|AAA68620.1| 544|Homo sapiens beta-hexosaminidase beta-... 91 1e-18
M13519-1|AAA51828.1| 572|Homo sapiens HEXB protein. 91 1e-18
BT009919-1|AAP88921.1| 556|Homo sapiens hexosaminidase B (beta ... 91 1e-18
BC017378-1|AAH17378.1| 556|Homo sapiens hexosaminidase B (beta ... 91 1e-18
AF378118-1|AAM46114.1| 556|Homo sapiens cervical cancer proto-o... 91 1e-18
S62076-1|AAD13932.1| 529|Homo sapiens HEXA protein. 87 2e-17
M16424-1|AAB00965.1| 529|Homo sapiens HEXA protein. 87 2e-17
M13520-1|AAA51827.1| 490|Homo sapiens HEXA protein. 87 2e-17
BC084537-1|AAH84537.1| 529|Homo sapiens hexosaminidase A (alpha... 87 2e-17
BC018927-1|AAH18927.1| 529|Homo sapiens hexosaminidase A (alpha... 87 2e-17
BC001138-1|AAH01138.2| 409|Homo sapiens HEXA protein protein. 87 2e-17
AK222502-1|BAD96222.1| 529|Homo sapiens hexosaminidase A prepro... 87 2e-17
BC021030-1|AAH21030.1| 309|Homo sapiens HEXA protein protein. 71 1e-12
M34906-1|AAA51829.1| 58|Homo sapiens beta-hexosaminidase beta-... 66 3e-11
AY643499-1|AAV48875.1| 331|Homo sapiens ENC-1AS protein. 66 3e-11
>M23294-1|AAA52645.1| 556|Homo sapiens beta-hexosaminidase
beta-subunit protein.
Length = 556
Score = 90.6 bits (215), Expect = 1e-18
Identities = 43/64 (67%), Positives = 47/64 (73%), Gaps = 1/64 (1%)
Frame = +3
Query: 3 DTSRHYLSLSKILKNIDAMAANKMNVLHWHIVDDQSFPYHSEKFPELSRLGAYH-PH*CT 179
DTSRHYL + ILK +DAMA NK NVLHWHIVDDQSFPY S FPELS G+Y H T
Sbjct: 208 DTSRHYLPVKIILKTLDAMAFNKFNVLHWHIVDDQSFPYQSITFPELSNKGSYSLSHVYT 267
Query: 180 PNAI 191
PN +
Sbjct: 268 PNDV 271
Score = 65.7 bits (153), Expect = 4e-11
Identities = 28/57 (49%), Positives = 38/57 (66%), Gaps = 1/57 (1%)
Frame = +2
Query: 176 YTKRDIEIVVKHAAERGVRVLPEFDVPGHTSSWGVAFPSILTKCYNGEEYV-GLGPI 343
YT D+ +V+++A RG+RVLPEFD PGHT SWG +LT CY+ + + GPI
Sbjct: 266 YTPNDVRMVIEYARLRGIRVLPEFDTPGHTLSWGKGQKDLLTPCYSRQNKLDSFGPI 322
>M19735-1|AAA68620.1| 544|Homo sapiens beta-hexosaminidase
beta-subunit protein.
Length = 544
Score = 90.6 bits (215), Expect = 1e-18
Identities = 43/64 (67%), Positives = 47/64 (73%), Gaps = 1/64 (1%)
Frame = +3
Query: 3 DTSRHYLSLSKILKNIDAMAANKMNVLHWHIVDDQSFPYHSEKFPELSRLGAYH-PH*CT 179
DTSRHYL + ILK +DAMA NK NVLHWHIVDDQSFPY S FPELS G+Y H T
Sbjct: 196 DTSRHYLPVKIILKTLDAMAFNKFNVLHWHIVDDQSFPYQSITFPELSNKGSYSLSHVYT 255
Query: 180 PNAI 191
PN +
Sbjct: 256 PNDV 259
Score = 65.7 bits (153), Expect = 4e-11
Identities = 28/57 (49%), Positives = 38/57 (66%), Gaps = 1/57 (1%)
Frame = +2
Query: 176 YTKRDIEIVVKHAAERGVRVLPEFDVPGHTSSWGVAFPSILTKCYNGEEYV-GLGPI 343
YT D+ +V+++A RG+RVLPEFD PGHT SWG +LT CY+ + + GPI
Sbjct: 254 YTPNDVRMVIEYARLRGIRVLPEFDTPGHTLSWGKGQKDLLTPCYSRQNKLDSFGPI 310
>M13519-1|AAA51828.1| 572|Homo sapiens HEXB protein.
Length = 572
Score = 90.6 bits (215), Expect = 1e-18
Identities = 43/64 (67%), Positives = 47/64 (73%), Gaps = 1/64 (1%)
Frame = +3
Query: 3 DTSRHYLSLSKILKNIDAMAANKMNVLHWHIVDDQSFPYHSEKFPELSRLGAYH-PH*CT 179
DTSRHYL + ILK +DAMA NK NVLHWHIVDDQSFPY S FPELS G+Y H T
Sbjct: 224 DTSRHYLPVKIILKTLDAMAFNKFNVLHWHIVDDQSFPYQSITFPELSNKGSYSLSHVYT 283
Query: 180 PNAI 191
PN +
Sbjct: 284 PNDV 287
Score = 65.7 bits (153), Expect = 4e-11
Identities = 28/57 (49%), Positives = 38/57 (66%), Gaps = 1/57 (1%)
Frame = +2
Query: 176 YTKRDIEIVVKHAAERGVRVLPEFDVPGHTSSWGVAFPSILTKCYNGEEYV-GLGPI 343
YT D+ +V+++A RG+RVLPEFD PGHT SWG +LT CY+ + + GPI
Sbjct: 282 YTPNDVRMVIEYARLRGIRVLPEFDTPGHTLSWGKGQKDLLTPCYSRQNKLDSFGPI 338
>BT009919-1|AAP88921.1| 556|Homo sapiens hexosaminidase B (beta
polypeptide) protein.
Length = 556
Score = 90.6 bits (215), Expect = 1e-18
Identities = 43/64 (67%), Positives = 47/64 (73%), Gaps = 1/64 (1%)
Frame = +3
Query: 3 DTSRHYLSLSKILKNIDAMAANKMNVLHWHIVDDQSFPYHSEKFPELSRLGAYH-PH*CT 179
DTSRHYL + ILK +DAMA NK NVLHWHIVDDQSFPY S FPELS G+Y H T
Sbjct: 208 DTSRHYLPVKIILKTLDAMAFNKFNVLHWHIVDDQSFPYQSITFPELSNKGSYSLSHVYT 267
Query: 180 PNAI 191
PN +
Sbjct: 268 PNDV 271
Score = 65.7 bits (153), Expect = 4e-11
Identities = 28/57 (49%), Positives = 38/57 (66%), Gaps = 1/57 (1%)
Frame = +2
Query: 176 YTKRDIEIVVKHAAERGVRVLPEFDVPGHTSSWGVAFPSILTKCYNGEEYV-GLGPI 343
YT D+ +V+++A RG+RVLPEFD PGHT SWG +LT CY+ + + GPI
Sbjct: 266 YTPNDVRMVIEYARLRGIRVLPEFDTPGHTLSWGKGQKDLLTPCYSRQNKLDSFGPI 322
>BC017378-1|AAH17378.1| 556|Homo sapiens hexosaminidase B (beta
polypeptide) protein.
Length = 556
Score = 90.6 bits (215), Expect = 1e-18
Identities = 43/64 (67%), Positives = 47/64 (73%), Gaps = 1/64 (1%)
Frame = +3
Query: 3 DTSRHYLSLSKILKNIDAMAANKMNVLHWHIVDDQSFPYHSEKFPELSRLGAYH-PH*CT 179
DTSRHYL + ILK +DAMA NK NVLHWHIVDDQSFPY S FPELS G+Y H T
Sbjct: 208 DTSRHYLPVKIILKTLDAMAFNKFNVLHWHIVDDQSFPYQSITFPELSNKGSYSLSHVYT 267
Query: 180 PNAI 191
PN +
Sbjct: 268 PNDV 271
Score = 65.7 bits (153), Expect = 4e-11
Identities = 28/57 (49%), Positives = 38/57 (66%), Gaps = 1/57 (1%)
Frame = +2
Query: 176 YTKRDIEIVVKHAAERGVRVLPEFDVPGHTSSWGVAFPSILTKCYNGEEYV-GLGPI 343
YT D+ +V+++A RG+RVLPEFD PGHT SWG +LT CY+ + + GPI
Sbjct: 266 YTPNDVRMVIEYARLRGIRVLPEFDTPGHTLSWGKGQKDLLTPCYSRQNKLDSFGPI 322
>AF378118-1|AAM46114.1| 556|Homo sapiens cervical cancer
proto-oncogene 7 protein.
Length = 556
Score = 90.6 bits (215), Expect = 1e-18
Identities = 43/64 (67%), Positives = 47/64 (73%), Gaps = 1/64 (1%)
Frame = +3
Query: 3 DTSRHYLSLSKILKNIDAMAANKMNVLHWHIVDDQSFPYHSEKFPELSRLGAYH-PH*CT 179
DTSRHYL + ILK +DAMA NK NVLHWHIVDDQSFPY S FPELS G+Y H T
Sbjct: 208 DTSRHYLPVKIILKTLDAMAFNKFNVLHWHIVDDQSFPYQSITFPELSNKGSYSLSHVYT 267
Query: 180 PNAI 191
PN +
Sbjct: 268 PNDV 271
Score = 65.7 bits (153), Expect = 4e-11
Identities = 28/57 (49%), Positives = 38/57 (66%), Gaps = 1/57 (1%)
Frame = +2
Query: 176 YTKRDIEIVVKHAAERGVRVLPEFDVPGHTSSWGVAFPSILTKCYNGEEYV-GLGPI 343
YT D+ +V+++A RG+RVLPEFD PGHT SWG +LT CY+ + + GPI
Sbjct: 266 YTPNDVRMVIEYARLRGIRVLPEFDTPGHTLSWGKGQKDLLTPCYSRQNKLDSFGPI 322
>S62076-1|AAD13932.1| 529|Homo sapiens HEXA protein.
Length = 529
Score = 86.6 bits (205), Expect = 2e-17
Identities = 37/55 (67%), Positives = 42/55 (76%)
Frame = +3
Query: 3 DTSRHYLSLSKILKNIDAMAANKMNVLHWHIVDDQSFPYHSEKFPELSRLGAYHP 167
DTSRHYL LS IL +D MA NK+NV HWH+VDD SFPY S FPEL R G+Y+P
Sbjct: 175 DTSRHYLPLSSILDTLDVMAYNKLNVFHWHLVDDPSFPYESFTFPELMRKGSYNP 229
Score = 70.9 bits (166), Expect = 1e-12
Identities = 30/57 (52%), Positives = 40/57 (70%), Gaps = 1/57 (1%)
Frame = +2
Query: 176 YTKRDIEIVVKHAAERGVRVLPEFDVPGHTSSWGVAFPSILTKCYNGEEYVG-LGPI 343
YT +D++ V+++A RG+RVL EFD PGHT SWG P +LT CY+G E G GP+
Sbjct: 234 YTAQDVKEVIEYARLRGIRVLAEFDTPGHTLSWGPGIPGLLTPCYSGSEPSGTFGPV 290
>M16424-1|AAB00965.1| 529|Homo sapiens HEXA protein.
Length = 529
Score = 86.6 bits (205), Expect = 2e-17
Identities = 37/55 (67%), Positives = 42/55 (76%)
Frame = +3
Query: 3 DTSRHYLSLSKILKNIDAMAANKMNVLHWHIVDDQSFPYHSEKFPELSRLGAYHP 167
DTSRHYL LS IL +D MA NK+NV HWH+VDD SFPY S FPEL R G+Y+P
Sbjct: 175 DTSRHYLPLSSILDTLDVMAYNKLNVFHWHLVDDPSFPYESFTFPELMRKGSYNP 229
Score = 70.9 bits (166), Expect = 1e-12
Identities = 30/57 (52%), Positives = 40/57 (70%), Gaps = 1/57 (1%)
Frame = +2
Query: 176 YTKRDIEIVVKHAAERGVRVLPEFDVPGHTSSWGVAFPSILTKCYNGEEYVG-LGPI 343
YT +D++ V+++A RG+RVL EFD PGHT SWG P +LT CY+G E G GP+
Sbjct: 234 YTAQDVKEVIEYARLRGIRVLAEFDTPGHTLSWGPGIPGLLTPCYSGSEPSGTFGPV 290
>M13520-1|AAA51827.1| 490|Homo sapiens HEXA protein.
Length = 490
Score = 86.6 bits (205), Expect = 2e-17
Identities = 37/55 (67%), Positives = 42/55 (76%)
Frame = +3
Query: 3 DTSRHYLSLSKILKNIDAMAANKMNVLHWHIVDDQSFPYHSEKFPELSRLGAYHP 167
DTSRHYL LS IL +D MA NK+NV HWH+VDD SFPY S FPEL R G+Y+P
Sbjct: 136 DTSRHYLPLSSILDTLDVMAYNKLNVFHWHLVDDPSFPYESFTFPELMRKGSYNP 190
Score = 70.9 bits (166), Expect = 1e-12
Identities = 30/57 (52%), Positives = 40/57 (70%), Gaps = 1/57 (1%)
Frame = +2
Query: 176 YTKRDIEIVVKHAAERGVRVLPEFDVPGHTSSWGVAFPSILTKCYNGEEYVG-LGPI 343
YT +D++ V+++A RG+RVL EFD PGHT SWG P +LT CY+G E G GP+
Sbjct: 195 YTAQDVKEVIEYARLRGIRVLAEFDTPGHTLSWGPGIPGLLTPCYSGSEPSGTFGPV 251
>BC084537-1|AAH84537.1| 529|Homo sapiens hexosaminidase A (alpha
polypeptide) protein.
Length = 529
Score = 86.6 bits (205), Expect = 2e-17
Identities = 37/55 (67%), Positives = 42/55 (76%)
Frame = +3
Query: 3 DTSRHYLSLSKILKNIDAMAANKMNVLHWHIVDDQSFPYHSEKFPELSRLGAYHP 167
DTSRHYL LS IL +D MA NK+NV HWH+VDD SFPY S FPEL R G+Y+P
Sbjct: 175 DTSRHYLPLSSILDTLDVMAYNKLNVFHWHLVDDPSFPYESFTFPELMRKGSYNP 229
Score = 70.9 bits (166), Expect = 1e-12
Identities = 30/57 (52%), Positives = 40/57 (70%), Gaps = 1/57 (1%)
Frame = +2
Query: 176 YTKRDIEIVVKHAAERGVRVLPEFDVPGHTSSWGVAFPSILTKCYNGEEYVG-LGPI 343
YT +D++ V+++A RG+RVL EFD PGHT SWG P +LT CY+G E G GP+
Sbjct: 234 YTAQDVKEVIEYARLRGIRVLAEFDTPGHTLSWGPGIPGLLTPCYSGSEPSGTFGPV 290
>BC018927-1|AAH18927.1| 529|Homo sapiens hexosaminidase A (alpha
polypeptide) protein.
Length = 529
Score = 86.6 bits (205), Expect = 2e-17
Identities = 37/55 (67%), Positives = 42/55 (76%)
Frame = +3
Query: 3 DTSRHYLSLSKILKNIDAMAANKMNVLHWHIVDDQSFPYHSEKFPELSRLGAYHP 167
DTSRHYL LS IL +D MA NK+NV HWH+VDD SFPY S FPEL R G+Y+P
Sbjct: 175 DTSRHYLPLSSILDTLDVMAYNKLNVFHWHLVDDPSFPYESFTFPELMRKGSYNP 229
Score = 70.9 bits (166), Expect = 1e-12
Identities = 30/57 (52%), Positives = 40/57 (70%), Gaps = 1/57 (1%)
Frame = +2
Query: 176 YTKRDIEIVVKHAAERGVRVLPEFDVPGHTSSWGVAFPSILTKCYNGEEYVG-LGPI 343
YT +D++ V+++A RG+RVL EFD PGHT SWG P +LT CY+G E G GP+
Sbjct: 234 YTAQDVKEVIEYARLRGIRVLAEFDTPGHTLSWGPGIPGLLTPCYSGSEPSGTFGPV 290
>BC001138-1|AAH01138.2| 409|Homo sapiens HEXA protein protein.
Length = 409
Score = 86.6 bits (205), Expect = 2e-17
Identities = 37/55 (67%), Positives = 42/55 (76%)
Frame = +3
Query: 3 DTSRHYLSLSKILKNIDAMAANKMNVLHWHIVDDQSFPYHSEKFPELSRLGAYHP 167
DTSRHYL LS IL +D MA NK+NV HWH+VDD SFPY S FPEL R G+Y+P
Sbjct: 55 DTSRHYLPLSSILDTLDVMAYNKLNVFHWHLVDDPSFPYESFTFPELMRKGSYNP 109
Score = 70.9 bits (166), Expect = 1e-12
Identities = 30/57 (52%), Positives = 40/57 (70%), Gaps = 1/57 (1%)
Frame = +2
Query: 176 YTKRDIEIVVKHAAERGVRVLPEFDVPGHTSSWGVAFPSILTKCYNGEEYVG-LGPI 343
YT +D++ V+++A RG+RVL EFD PGHT SWG P +LT CY+G E G GP+
Sbjct: 114 YTAQDVKEVIEYARLRGIRVLAEFDTPGHTLSWGPGIPGLLTPCYSGSEPSGTFGPV 170
>AK222502-1|BAD96222.1| 529|Homo sapiens hexosaminidase A
preproprotein variant protein.
Length = 529
Score = 86.6 bits (205), Expect = 2e-17
Identities = 37/55 (67%), Positives = 42/55 (76%)
Frame = +3
Query: 3 DTSRHYLSLSKILKNIDAMAANKMNVLHWHIVDDQSFPYHSEKFPELSRLGAYHP 167
DTSRHYL LS IL +D MA NK+NV HWH+VDD SFPY S FPEL R G+Y+P
Sbjct: 175 DTSRHYLPLSSILDTLDVMAYNKLNVFHWHLVDDPSFPYESFTFPELMRKGSYNP 229
Score = 70.9 bits (166), Expect = 1e-12
Identities = 30/57 (52%), Positives = 40/57 (70%), Gaps = 1/57 (1%)
Frame = +2
Query: 176 YTKRDIEIVVKHAAERGVRVLPEFDVPGHTSSWGVAFPSILTKCYNGEEYVG-LGPI 343
YT +D++ V+++A RG+RVL EFD PGHT SWG P +LT CY+G E G GP+
Sbjct: 234 YTAQDVKEVIEYARLRGIRVLAEFDTPGHTLSWGPGIPGLLTPCYSGSEPSGTFGPV 290
>BC021030-1|AAH21030.1| 309|Homo sapiens HEXA protein protein.
Length = 309
Score = 70.9 bits (166), Expect = 1e-12
Identities = 30/57 (52%), Positives = 40/57 (70%), Gaps = 1/57 (1%)
Frame = +2
Query: 176 YTKRDIEIVVKHAAERGVRVLPEFDVPGHTSSWGVAFPSILTKCYNGEEYVG-LGPI 343
YT +D++ V+++A RG+RVL EFD PGHT SWG P +LT CY+G E G GP+
Sbjct: 14 YTAQDVKEVIEYARLRGIRVLAEFDTPGHTLSWGPGIPGLLTPCYSGSEPSGTFGPV 70
>M34906-1|AAA51829.1| 58|Homo sapiens beta-hexosaminidase
beta-subunit protein.
Length = 58
Score = 66.1 bits (154), Expect = 3e-11
Identities = 31/46 (67%), Positives = 33/46 (71%), Gaps = 1/46 (2%)
Frame = +3
Query: 57 MAANKMNVLHWHIVDDQSFPYHSEKFPELSRLGAYH-PH*CTPNAI 191
MA NK NVLHWHIVDDQSFPY S FPELS G+Y H TPN +
Sbjct: 1 MAFNKFNVLHWHIVDDQSFPYQSITFPELSNKGSYSLSHVYTPNDV 46
>AY643499-1|AAV48875.1| 331|Homo sapiens ENC-1AS protein.
Length = 331
Score = 66.1 bits (154), Expect = 3e-11
Identities = 31/46 (67%), Positives = 33/46 (71%), Gaps = 1/46 (2%)
Frame = +3
Query: 57 MAANKMNVLHWHIVDDQSFPYHSEKFPELSRLGAYH-PH*CTPNAI 191
MA NK NVLHWHIVDDQSFPY S FPELS G+Y H TPN +
Sbjct: 1 MAFNKFNVLHWHIVDDQSFPYQSITFPELSNKGSYSLSHVYTPNDV 46
Score = 65.7 bits (153), Expect = 4e-11
Identities = 28/57 (49%), Positives = 38/57 (66%), Gaps = 1/57 (1%)
Frame = +2
Query: 176 YTKRDIEIVVKHAAERGVRVLPEFDVPGHTSSWGVAFPSILTKCYNGEEYV-GLGPI 343
YT D+ +V+++A RG+RVLPEFD PGHT SWG +LT CY+ + + GPI
Sbjct: 41 YTPNDVRMVIEYARLRGIRVLPEFDTPGHTLSWGKGQKDLLTPCYSRQNKLDSFGPI 97
Database: human
Posted date: Oct 23, 2007 1:18 PM
Number of letters in database: 76,859,062
Number of sequences in database: 237,096
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 51,131,023
Number of Sequences: 237096
Number of extensions: 1004671
Number of successful extensions: 2056
Number of sequences better than 10.0: 16
Number of HSP's better than 10.0 without gapping: 1990
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 2056
length of database: 76,859,062
effective HSP length: 80
effective length of database: 57,891,382
effective search space used: 2026198370
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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