BLASTX 2.2.12 [Aug-07-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= I10A02NGRL0003_F14 (612 letters) Database: uniref50 1,657,284 sequences; 575,637,011 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value UniRef50_Q967G9 Cluster: Ferrochelatase precursor; n=2; Endopter... 255 5e-67 UniRef50_P22830 Cluster: Ferrochelatase, mitochondrial precursor... 220 2e-56 UniRef50_Q5AVC8 Cluster: Ferrochelatase; n=9; Fungi/Metazoa grou... 180 2e-44 UniRef50_A4RKF0 Cluster: Ferrochelatase; n=14; Pezizomycotina|Re... 166 3e-40 UniRef50_UPI0001509D16 Cluster: ferrochelatase family protein; n... 163 4e-39 UniRef50_P16622 Cluster: Ferrochelatase, mitochondrial precursor... 162 7e-39 UniRef50_Q4SRE0 Cluster: Ferrochelatase; n=1; Tetraodon nigrovir... 154 2e-36 UniRef50_Q54IA8 Cluster: Ferrochelatase; n=1; Dictyostelium disc... 147 2e-34 UniRef50_UPI00015BC7F1 Cluster: UPI00015BC7F1 related cluster; n... 136 5e-31 UniRef50_P42045 Cluster: Ferrochelatase-2, chloroplast precursor... 135 7e-31 UniRef50_Q747F5 Cluster: Ferrochelatase; n=7; Desulfuromonadales... 132 8e-30 UniRef50_O04921 Cluster: Ferrochelatase-2, chloroplast precursor... 128 8e-29 UniRef50_P42044 Cluster: Ferrochelatase-2, chloroplast precursor... 126 3e-28 UniRef50_Q9ATG7 Cluster: Ferrochelatase; n=1; Polytomella sp. Pr... 124 1e-27 UniRef50_A7T926 Cluster: Predicted protein; n=1; Nematostella ve... 121 2e-26 UniRef50_O67083 Cluster: Ferrochelatase; n=1; Aquifex aeolicus|R... 120 3e-26 UniRef50_Q2RZ44 Cluster: Ferrochelatase; n=1; Salinibacter ruber... 119 6e-26 UniRef50_Q3A6H8 Cluster: Ferrochelatase; n=1; Pelobacter carbino... 117 2e-25 UniRef50_Q6APB0 Cluster: Ferrochelatase; n=1; Desulfotalea psych... 116 4e-25 UniRef50_Q1K4G8 Cluster: Ferrochelatase; n=1; Desulfuromonas ace... 115 1e-24 UniRef50_Q6BFD7 Cluster: Ferrochelatase (EC 4.99.1.1), putative;... 113 3e-24 UniRef50_P57777 Cluster: Ferrochelatase; n=12; Alphaproteobacter... 109 4e-23 UniRef50_Q4UJN9 Cluster: Ferrochelatase; n=16; Rickettsiales|Rep... 107 2e-22 UniRef50_Q2RN84 Cluster: Ferrochelatase; n=2; Alphaproteobacteri... 107 3e-22 UniRef50_A7H9E2 Cluster: Ferrochelatase; n=2; Anaeromyxobacter|R... 107 3e-22 UniRef50_Q7VD58 Cluster: Ferrochelatase; n=20; Cyanobacteria|Rep... 106 4e-22 UniRef50_Q1V1A3 Cluster: Ferrochelatase; n=2; Candidatus Pelagib... 104 1e-21 UniRef50_Q1NMT4 Cluster: Ferrochelatase; n=2; delta proteobacter... 104 1e-21 UniRef50_A3EV75 Cluster: Protoheme ferro-lyase; n=1; Leptospiril... 104 1e-21 UniRef50_Q2S1S2 Cluster: Ferrochelatase; n=1; Salinibacter ruber... 103 3e-21 UniRef50_Q833G5 Cluster: Ferrochelatase; n=1; Enterococcus faeca... 100 5e-20 UniRef50_A5UU36 Cluster: Ferrochelatase; n=3; Chloroflexi (class... 99 7e-20 UniRef50_Q5PA48 Cluster: Ferrochelatase; n=2; Anaplasma|Rep: Fer... 99 1e-19 UniRef50_Q5YU18 Cluster: Ferrochelatase; n=14; Bacteria|Rep: Fer... 97 2e-19 UniRef50_Q5DEU6 Cluster: SJCHGC05531 protein; n=1; Schistosoma j... 96 7e-19 UniRef50_P56107 Cluster: Ferrochelatase; n=5; Helicobacteraceae|... 94 2e-18 UniRef50_Q5GRR7 Cluster: Ferrochelatase; n=1; Wolbachia endosymb... 94 3e-18 UniRef50_Q8FTB1 Cluster: Ferrochelatase; n=24; Actinomycetales|R... 92 1e-17 UniRef50_Q2GH68 Cluster: Ferrochelatase; n=3; canis group|Rep: F... 91 1e-17 UniRef50_Q0BWA5 Cluster: Ferrochelatase; n=1; Hyphomonas neptuni... 90 4e-17 UniRef50_A6Q2Y9 Cluster: Ferrochelatase; n=2; Epsilonproteobacte... 90 4e-17 UniRef50_Q9RV98 Cluster: Ferrochelatase; n=1; Deinococcus radiod... 87 3e-16 UniRef50_P43868 Cluster: Ferrochelatase; n=40; Bacteria|Rep: Fer... 86 5e-16 UniRef50_Q2BIY0 Cluster: Ferrochelatase; n=2; Gammaproteobacteri... 85 1e-15 UniRef50_P43413 Cluster: Ferrochelatase; n=28; Gammaproteobacter... 85 1e-15 UniRef50_Q72L32 Cluster: Ferrochelatase; n=2; Thermus thermophil... 84 2e-15 UniRef50_Q5FSJ9 Cluster: Ferrochelatase; n=1; Gluconobacter oxyd... 82 9e-15 UniRef50_A6DEA9 Cluster: Ferrochelatase; n=1; Caminibacter media... 82 1e-14 UniRef50_Q8DFM2 Cluster: Ferrochelatase; n=16; Gammaproteobacter... 82 1e-14 UniRef50_Q2GCY1 Cluster: Ferrochelatase; n=1; Neorickettsia senn... 81 2e-14 UniRef50_Q8GCV0 Cluster: Ferrochelatase; n=1; Leptospira biflexa... 81 2e-14 UniRef50_Q7VHH1 Cluster: Ferrochelatase; n=1; Helicobacter hepat... 81 2e-14 UniRef50_UPI0000E4A92D Cluster: PREDICTED: similar to ferrochela... 56 3e-14 UniRef50_Q3AEU4 Cluster: Ferrochelatase; n=1; Carboxydothermus h... 79 6e-14 UniRef50_Q62HD1 Cluster: Ferrochelatase; n=82; cellular organism... 79 6e-14 UniRef50_A6VXF8 Cluster: Ferrochelatase; n=1; Marinomonas sp. MW... 79 1e-13 UniRef50_Q9PI08 Cluster: Ferrochelatase; n=16; Campylobacter|Rep... 79 1e-13 UniRef50_Q1ITV1 Cluster: Ferrochelatase; n=2; Acidobacteria|Rep:... 78 1e-13 UniRef50_Q67T48 Cluster: Ferrochelatase; n=1; Symbiobacterium th... 77 3e-13 UniRef50_Q03Z41 Cluster: Ferrochelatase; n=1; Leuconostoc mesent... 77 3e-13 UniRef50_P57874 Cluster: Ferrochelatase; n=1; Pasteurella multoc... 77 4e-13 UniRef50_A5EXB1 Cluster: Ferrochelatase; n=1; Dichelobacter nodo... 76 8e-13 UniRef50_A6QAW0 Cluster: Ferrochelatase; n=1; Sulfurovum sp. NBC... 75 1e-12 UniRef50_UPI0000DAE46A Cluster: hypothetical protein Rgryl_01000... 75 1e-12 UniRef50_A1K8P4 Cluster: Ferrochelatase; n=3; Betaproteobacteria... 75 1e-12 UniRef50_Q5QVZ8 Cluster: Ferrochelatase; n=17; Gammaproteobacter... 75 1e-12 UniRef50_Q6F7N0 Cluster: Ferrochelatase; n=5; Moraxellaceae|Rep:... 75 1e-12 UniRef50_Q8D226 Cluster: Ferrochelatase; n=1; Wigglesworthia glo... 75 2e-12 UniRef50_O07401 Cluster: Ferrochelatase; n=1; Mycobacterium aviu... 75 2e-12 UniRef50_Q1ZEV1 Cluster: Ferrochelatase; n=1; Psychromonas sp. C... 74 2e-12 UniRef50_Q8IFR0 Cluster: Ferrochelatase; n=10; Plasmodium|Rep: F... 74 2e-12 UniRef50_P37408 Cluster: Ferrochelatase; n=5; Enterobacteriaceae... 74 2e-12 UniRef50_Q97R30 Cluster: Ferrochelatase; n=18; Streptococcus|Rep... 72 9e-12 UniRef50_Q9CFB4 Cluster: Ferrochelatase; n=3; Lactococcus lactis... 71 2e-11 UniRef50_A3QC13 Cluster: Ferrochelatase; n=5; Gammaproteobacteri... 71 3e-11 UniRef50_Q9PFU1 Cluster: Ferrochelatase; n=13; Xanthomonadaceae|... 71 3e-11 UniRef50_Q5P1H1 Cluster: Ferrochelatase; n=3; Betaproteobacteria... 70 4e-11 UniRef50_Q6MAW8 Cluster: Ferrochelatase; n=5; Bacteria|Rep: Ferr... 70 4e-11 UniRef50_Q8EBZ7 Cluster: Ferrochelatase 2; n=48; Proteobacteria|... 70 4e-11 UniRef50_Q9Z7V1 Cluster: Ferrochelatase; n=12; Chlamydiaceae|Rep... 69 7e-11 UniRef50_Q81TU9 Cluster: Ferrochelatase 2; n=76; Bacillales|Rep:... 69 9e-11 UniRef50_Q82KJ6 Cluster: Ferrochelatase; n=10; Actinobacteria (c... 69 1e-10 UniRef50_Q5NFT3 Cluster: Ferrochelatase; n=11; Francisella tular... 68 2e-10 UniRef50_P28602 Cluster: Ferrochelatase; n=19; Proteobacteria|Re... 67 4e-10 UniRef50_Q28VQ2 Cluster: Ferrochelatase; n=9; Rhodobacteraceae|R... 66 5e-10 UniRef50_A3TKF4 Cluster: Putative ferrochelatase; n=3; Bacteria|... 66 5e-10 UniRef50_Q82UK8 Cluster: Ferrochelatase; n=2; Betaproteobacteria... 66 6e-10 UniRef50_A3U6F4 Cluster: Ferrochelatase; n=14; Bacteroidetes|Rep... 66 8e-10 UniRef50_Q88XC3 Cluster: Ferrochelatase; n=3; Lactobacillus|Rep:... 66 8e-10 UniRef50_Q98H61 Cluster: Ferrochelatase; n=31; Alphaproteobacter... 63 4e-09 UniRef50_A6DTB4 Cluster: Ferrochelatase; n=1; Lentisphaera arane... 62 1e-08 UniRef50_Q6AB01 Cluster: Ferrochelatase, HemH; n=1; Propionibact... 61 2e-08 UniRef50_Q8XW32 Cluster: Ferrochelatase; n=17; Proteobacteria|Re... 59 9e-08 UniRef50_P72183 Cluster: Ferrochelatase; n=1; Propionibacterium ... 58 1e-07 UniRef50_P57779 Cluster: Ferrochelatase; n=9; Bacteria|Rep: Ferr... 57 3e-07 UniRef50_Q5ZYE7 Cluster: Ferrochelatase; n=5; Legionella pneumop... 56 5e-07 UniRef50_A0L8B7 Cluster: Ferrochelatase; n=1; Magnetococcus sp. ... 55 2e-06 UniRef50_A5V0K6 Cluster: Ferrochelatase; n=2; Roseiflexus|Rep: F... 54 2e-06 UniRef50_Q4JSM9 Cluster: Ferrochelatase; n=1; Corynebacterium je... 53 5e-06 UniRef50_A7BBG3 Cluster: Putative uncharacterized protein; n=1; ... 53 6e-06 UniRef50_Q1DC34 Cluster: Ferrochelatase; n=3; Myxococcales|Rep: ... 51 2e-05 UniRef50_Q9K097 Cluster: Ferrochelatase; n=5; Neisseria|Rep: Fer... 51 2e-05 UniRef50_Q4QE43 Cluster: Ferrochelatase-like protein; n=21; Leis... 47 4e-04 UniRef50_Q6L0G9 Cluster: Ferrochelatase; n=2; Thermoplasmatales|... 47 4e-04 UniRef50_Q9HVD7 Cluster: Ferrochelatase; n=19; Pseudomonadaceae|... 46 7e-04 UniRef50_Q6MHT3 Cluster: Ferrochelatase; n=1; Bdellovibrio bacte... 46 7e-04 UniRef50_Q83FA4 Cluster: Ferrochelatase; n=4; Coxiella burnetii|... 44 0.003 UniRef50_Q8YNF0 Cluster: Alr4616 protein; n=9; Cyanobacteria|Rep... 43 0.005 UniRef50_Q8EY34 Cluster: Ferrochelatase; n=5; Leptospira|Rep: Fe... 42 0.012 UniRef50_A7BEQ8 Cluster: Putative uncharacterized protein; n=1; ... 42 0.015 UniRef50_Q9HLB8 Cluster: Ferrochelatase; n=2; Thermoplasma|Rep: ... 40 0.062 UniRef50_Q7MXP4 Cluster: Ferrochelatase; n=1; Porphyromonas ging... 39 0.081 UniRef50_Q97UK4 Cluster: Putative uncharacterized protein; n=1; ... 36 0.57 UniRef50_Q9PBW1 Cluster: Putative uncharacterized protein; n=5; ... 36 0.76 UniRef50_Q11W64 Cluster: CHU large protein; candidate b-glycosid... 36 1.0 UniRef50_Q1GGC1 Cluster: 3-hydroxyacyl-CoA dehydrogenase NAD-bin... 35 1.8 UniRef50_UPI0001555B1E Cluster: PREDICTED: similar to Transmembr... 34 2.3 UniRef50_Q8I5I1 Cluster: Putative uncharacterized protein; n=1; ... 34 2.3 UniRef50_Q64SD9 Cluster: Putative uncharacterized protein; n=1; ... 34 3.1 UniRef50_A3PTJ5 Cluster: NAD-dependent epimerase/dehydratase; n=... 34 3.1 UniRef50_Q4QGN5 Cluster: Putative uncharacterized protein; n=3; ... 33 5.3 UniRef50_A6RAS7 Cluster: Putative uncharacterized protein; n=1; ... 33 5.3 UniRef50_Q9A450 Cluster: Sensor protein; n=1; Caulobacter vibrio... 33 7.1 UniRef50_A6TNA9 Cluster: ABC transporter related; n=1; Alkaliphi... 33 7.1 UniRef50_A7CYB9 Cluster: Ethanolamine ammonia-lyase large subuni... 32 9.3 UniRef50_Q4PDI5 Cluster: Putative uncharacterized protein; n=1; ... 32 9.3 UniRef50_Q64E20 Cluster: Putative uncharacterized protein; n=1; ... 32 9.3 >UniRef50_Q967G9 Cluster: Ferrochelatase precursor; n=2; Endopterygota|Rep: Ferrochelatase precursor - Chironomus sp. YKL-2001 Length = 393 Score = 255 bits (625), Expect = 5e-67 Identities = 117/189 (61%), Positives = 147/189 (77%) Frame = +1 Query: 1 ERVVIFSQYPQYSCATTGSSLNAVADYYKNKQIPRDIRFSLIERWGSHPLLARVFAERIK 180 ERVVIFSQYPQYSCAT+GSS N++ ++ K+ +I++S+I+RW +H LL + FAERIK Sbjct: 153 ERVVIFSQYPQYSCATSGSSFNSIFTHFGGKKPNSNIKWSMIDRWPTHHLLVKTFAERIK 212 Query: 181 EKLTLFPAGVRDQVLILFTAHSLPLKAVSRGDTYPHEVAASVSATVSELGAVNPHRLVWQ 360 EKL F RD ++LF+AHSLPLK V RGD YP EV A+V+A ++EL NP+ LVWQ Sbjct: 213 EKLAEFSPDKRDDAILLFSAHSLPLKNVRRGDAYPSEVGATVNAVMAELNYCNPYCLVWQ 272 Query: 361 SKVGPLPWLQPYTDDAIKSYAKQGVKYMILVPIAFVNEHIETLHELDIEYCDEVAKEAGI 540 SKVGPLPWL+P+TDDAIK YA +G K +L+PIAFVNEHIETLHELDIEYC ++AKE + Sbjct: 273 SKVGPLPWLEPFTDDAIKMYAAKGKKNFVLIPIAFVNEHIETLHELDIEYCHDLAKEVKV 332 Query: 541 VQIERAETP 567 +I RA P Sbjct: 333 EKILRAAAP 341 >UniRef50_P22830 Cluster: Ferrochelatase, mitochondrial precursor; n=56; Fungi/Metazoa group|Rep: Ferrochelatase, mitochondrial precursor - Homo sapiens (Human) Length = 423 Score = 220 bits (538), Expect = 2e-56 Identities = 101/188 (53%), Positives = 136/188 (72%) Frame = +1 Query: 1 ERVVIFSQYPQYSCATTGSSLNAVADYYKNKQIPRDIRFSLIERWGSHPLLARVFAERIK 180 ER + F+QYPQYSC+TTGSSLNA+ YY +++S I+RW +H LL + FA+ I Sbjct: 183 ERAIAFTQYPQYSCSTTGSSLNAIYRYYNQVGRKPTMKWSTIDRWPTHHLLIQCFADHIL 242 Query: 181 EKLTLFPAGVRDQVLILFTAHSLPLKAVSRGDTYPHEVAASVSATVSELGAVNPHRLVWQ 360 ++L FP R +V+ILF+AHSLP+ V+RGD YP EV+A+V + L NP+RLVWQ Sbjct: 243 KELDHFPLEKRSEVVILFSAHSLPMSVVNRGDPYPQEVSATVQKVMERLEYCNPYRLVWQ 302 Query: 361 SKVGPLPWLQPYTDDAIKSYAKQGVKYMILVPIAFVNEHIETLHELDIEYCDEVAKEAGI 540 SKVGP+PWL P TD++IK ++G K ++LVPIAF ++HIETL+ELDIEY +AKE G+ Sbjct: 303 SKVGPMPWLGPQTDESIKGLCERGRKNILLVPIAFTSDHIETLYELDIEYSQVLAKECGV 362 Query: 541 VQIERAET 564 I RAE+ Sbjct: 363 ENIRRAES 370 >UniRef50_Q5AVC8 Cluster: Ferrochelatase; n=9; Fungi/Metazoa group|Rep: Ferrochelatase - Emericella nidulans (Aspergillus nidulans) Length = 419 Score = 180 bits (438), Expect = 2e-44 Identities = 90/192 (46%), Positives = 127/192 (66%), Gaps = 9/192 (4%) Frame = +1 Query: 4 RVVIFSQYPQYSCATTGSSLNAVADY---YKNKQIPRD------IRFSLIERWGSHPLLA 156 R V F+QYPQYSC+TTGSSLN + + + K+ D I++S+I+RW +HP L Sbjct: 170 RAVAFTQYPQYSCSTTGSSLNELWKWRTRLEGKRANCDVDATGTIQWSVIDRWPTHPGLI 229 Query: 157 RVFAERIKEKLTLFPAGVRDQVLILFTAHSLPLKAVSRGDTYPHEVAASVSATVSELGAV 336 FA I+++L +P R+ V++LF+AHSLP+ V+RGD YP EVAA+V A + L Sbjct: 230 EAFARNIEDQLKTYPEEKRNSVVLLFSAHSLPMSVVNRGDPYPAEVAATVHAVMQRLNFS 289 Query: 337 NPHRLVWQSKVGPLPWLQPYTDDAIKSYAKQGVKYMILVPIAFVNEHIETLHELDIEYCD 516 NP+RL WQS+VGP WL T D ++ Y K+G ++LVPIAF ++HIETL+ELD+E + Sbjct: 290 NPYRLCWQSQVGPSAWLGAQTSDTVQEYVKRGQTDLVLVPIAFTSDHIETLYELDLEVME 349 Query: 517 EVAKEAGIVQIE 552 E A G+ + E Sbjct: 350 E-ANHPGVKRAE 360 >UniRef50_A4RKF0 Cluster: Ferrochelatase; n=14; Pezizomycotina|Rep: Ferrochelatase - Magnaporthe grisea (Rice blast fungus) (Pyricularia grisea) Length = 438 Score = 166 bits (404), Expect = 3e-40 Identities = 86/200 (43%), Positives = 123/200 (61%), Gaps = 17/200 (8%) Frame = +1 Query: 4 RVVIFSQYPQYSCATTGSSLN-------------AVADYYKNKQIPR----DIRFSLIER 132 R V F+QYPQYSC+TTGSSLN A AD + + + I++S+I+R Sbjct: 180 RAVAFTQYPQYSCSTTGSSLNELWKWRQRLEGKSAEADGGSSAALSKVNDGTIQWSVIDR 239 Query: 133 WGSHPLLARVFAERIKEKLTLFPAGVRDQVLILFTAHSLPLKAVSRGDTYPHEVAASVSA 312 W H L FA+ I+ KL +P R++ +++F+AHSLP+ V+RGD YP EVAA+V Sbjct: 240 WPVHAGLVEAFAQNIEAKLAEYPEERRNKAVLMFSAHSLPMTVVNRGDPYPAEVAATVYG 299 Query: 313 TVSELGAVNPHRLVWQSKVGPLPWLQPYTDDAIKSYAKQGVKYMILVPIAFVNEHIETLH 492 + LG NP+RL WQS+VGP PWL P T +++ Y +G K ++L+PIAF ++HIETL Sbjct: 300 VMQRLGFSNPYRLCWQSQVGPQPWLGPQTSTSVEEYVSKGQKDIVLIPIAFTSDHIETLF 359 Query: 493 ELDIEYCDEVAKEAGIVQIE 552 ELD E + + ++E Sbjct: 360 ELDQEVIGDSGHPDTVKRVE 379 >UniRef50_UPI0001509D16 Cluster: ferrochelatase family protein; n=1; Tetrahymena thermophila SB210|Rep: ferrochelatase family protein - Tetrahymena thermophila SB210 Length = 369 Score = 163 bits (395), Expect = 4e-39 Identities = 79/189 (41%), Positives = 113/189 (59%), Gaps = 1/189 (0%) Frame = +1 Query: 1 ERVVIFSQYPQYSCATTGSSLNAVADYYKNKQIPRDIRFSLIERWGSHPLLARVFAERIK 180 E+ V FSQYPQYSC T G+++ + K + +I+RW +HP + + + Sbjct: 134 EKFVFFSQYPQYSCTTAGNNIREALKHLKEQYKNHGKTIHVIDRWYNHPGYVKTISRLLS 193 Query: 181 EKL-TLFPAGVRDQVLILFTAHSLPLKAVSRGDTYPHEVAASVSATVSELGAVNPHRLVW 357 E L F RD VLILF+AHSLP V +GDTYP+E+ + + + E NPHR+VW Sbjct: 194 EDLKNNFKEEDRDNVLILFSAHSLPFDFVKQGDTYPYEIGTTANLVIQEAKLKNPHRVVW 253 Query: 358 QSKVGPLPWLQPYTDDAIKSYAKQGVKYMILVPIAFVNEHIETLHELDIEYCDEVAKEAG 537 QSKVG WL P T A++ + QG K +ILVP+ F ++H+ETL+ELD+EY E ++ Sbjct: 254 QSKVGFQQWLAPNTMHALEQASNQGWKNVILVPLGFTSDHLETLYELDLEYIKESQEKLK 313 Query: 538 IVQIERAET 564 +I RA + Sbjct: 314 FNKIIRARS 322 >UniRef50_P16622 Cluster: Ferrochelatase, mitochondrial precursor; n=11; Ascomycota|Rep: Ferrochelatase, mitochondrial precursor - Saccharomyces cerevisiae (Baker's yeast) Length = 393 Score = 162 bits (393), Expect = 7e-39 Identities = 79/168 (47%), Positives = 113/168 (67%) Frame = +1 Query: 1 ERVVIFSQYPQYSCATTGSSLNAVADYYKNKQIPRDIRFSLIERWGSHPLLARVFAERIK 180 ++ V FSQYP +S +TTGSS+N + K R I +S+I+RW ++ L + F+E I Sbjct: 155 KKAVAFSQYPHFSYSTTGSSINELWRQIKALDSERSISWSVIDRWPTNEGLIKAFSENIT 214 Query: 181 EKLTLFPAGVRDQVLILFTAHSLPLKAVSRGDTYPHEVAASVSATVSELGAVNPHRLVWQ 360 +KL FP VRD+V++LF+AHSLP+ V+ GD YP EVAA+V + +L NP+RLVWQ Sbjct: 215 KKLQEFPQPVRDKVVLLFSAHSLPMDVVNTGDAYPAEVAATVYNIMQKLKFKNPYRLVWQ 274 Query: 361 SKVGPLPWLQPYTDDAIKSYAKQGVKYMILVPIAFVNEHIETLHELDI 504 S+VGP PWL T + I + V ++ +PIAF ++HIETLHE+D+ Sbjct: 275 SQVGPKPWLGAQTAE-IAEFLGPKVDGLMFIPIAFTSDHIETLHEIDL 321 >UniRef50_Q4SRE0 Cluster: Ferrochelatase; n=1; Tetraodon nigroviridis|Rep: Ferrochelatase - Tetraodon nigroviridis (Green puffer) Length = 409 Score = 154 bits (373), Expect = 2e-36 Identities = 71/127 (55%), Positives = 89/127 (70%) Frame = +1 Query: 1 ERVVIFSQYPQYSCATTGSSLNAVADYYKNKQIPRDIRFSLIERWGSHPLLARVFAERIK 180 ER V F+QYPQYSC+TTGSSLNA+ YY N+ + +S+I+RW +HPLL FAE I+ Sbjct: 119 ERAVAFTQYPQYSCSTTGSSLNAIYRYYSNRGERPKMSWSVIDRWPTHPLLVECFAEHIQ 178 Query: 181 EKLTLFPAGVRDQVLILFTAHSLPLKAVSRGDTYPHEVAASVSATVSELGAVNPHRLVWQ 360 +L FP RD V+ILF+AHSLP+ V+RGD YP EV A+V + LG NP+RLVWQ Sbjct: 179 NELLQFPEEKRDDVVILFSAHSLPMAVVNRGDPYPQEVGATVQRVMERLGHCNPYRLVWQ 238 Query: 361 SKVGPLP 381 SK P P Sbjct: 239 SKQPPSP 245 >UniRef50_Q54IA8 Cluster: Ferrochelatase; n=1; Dictyostelium discoideum AX4|Rep: Ferrochelatase - Dictyostelium discoideum AX4 Length = 423 Score = 147 bits (357), Expect = 2e-34 Identities = 85/210 (40%), Positives = 121/210 (57%), Gaps = 22/210 (10%) Frame = +1 Query: 1 ERVVIFSQYPQYSCATTGSSLNAVADYYKNKQIPRDIRFSLIERWGSHPLLARVFAERIK 180 ERVV FSQYPQYSC TTGSSLN + + KQ+ ++S+I+RW H +IK Sbjct: 160 ERVVAFSQYPQYSCTTTGSSLNNLWKTLEEKQMQSKFKWSVIDRWQDHKGFIDATIHKIK 219 Query: 181 EKLTLFPAGVRD---------------QVLILFTAHSLPLKAVSRGDTYPHEVAASVSAT 315 + F + +R+ + +++F+AHSLP+ V +GD YP EVA +V Sbjct: 220 KAYNQFNSKLRELDIDDVDANNNNNNNKPVLVFSAHSLPMSTVEKGDPYPQEVAETVCRV 279 Query: 316 VSELGAVNPHR-------LVWQSKVGPLPWLQPYTDDAIKSYAKQGVKYMILVPIAFVNE 474 + LG + L WQSKVGPLPWL P T I+ AK+G + I++PIAF ++ Sbjct: 280 MDGLGIRDEETGKPLEYILAWQSKVGPLPWLSPKTSFVIEQLAKKG-RNAIVIPIAFTSD 338 Query: 475 HIETLHELDIEYCDEVAKEAGIVQIERAET 564 HIETL E+DIE +AK+ G+ + R+E+ Sbjct: 339 HIETLSEIDIE-LQHLAKKCGMKLLVRSES 367 >UniRef50_UPI00015BC7F1 Cluster: UPI00015BC7F1 related cluster; n=1; unknown|Rep: UPI00015BC7F1 UniRef100 entry - unknown Length = 312 Score = 136 bits (328), Expect = 5e-31 Identities = 73/187 (39%), Positives = 106/187 (56%) Frame = +1 Query: 4 RVVIFSQYPQYSCATTGSSLNAVADYYKNKQIPRDIRFSLIERWGSHPLLARVFAERIKE 183 ++V+ YP YS TTGSS +K + +D I + HPL + + E IK Sbjct: 115 KIVLLPLYPHYSSTTTGSSFKEFYRLFKKSSL-KDTPVKEIRDYHDHPLFIKAWTENIKN 173 Query: 184 KLTLFPAGVRDQVLILFTAHSLPLKAVSRGDTYPHEVAASVSATVSELGAVNPHRLVWQS 363 +G+ D+ ILF+AHSLP K + + D Y ++ SV + N + + +QS Sbjct: 174 ------SGIDDEYFILFSAHSLPQKIIDKKDPYKDQIEKSVELIMKNFK--NKYMISYQS 225 Query: 364 KVGPLPWLQPYTDDAIKSYAKQGVKYMILVPIAFVNEHIETLHELDIEYCDEVAKEAGIV 543 KVGP+ WL+P TD I++ AKQG+K + LVPI+FV+EH ETL+E+D Y +AKE GI Sbjct: 226 KVGPVKWLEPPTDKTIENLAKQGIKKLCLVPISFVSEHSETLYEMDYLY-KNMAKELGIE 284 Query: 544 QIERAET 564 +R T Sbjct: 285 HFKRVPT 291 >UniRef50_P42045 Cluster: Ferrochelatase-2, chloroplast precursor; n=9; cellular organisms|Rep: Ferrochelatase-2, chloroplast precursor - Hordeum vulgare (Barley) Length = 484 Score = 135 bits (327), Expect = 7e-31 Identities = 69/183 (37%), Positives = 114/183 (62%), Gaps = 4/183 (2%) Frame = +1 Query: 4 RVVIFSQYPQYSCATTGSSLNAVADYYKNKQIPRDIRFSLIERWGSHPLLARVFAERIKE 183 ++V+ YPQYS +T+GSS+ + + K + S+IE W + A+ I++ Sbjct: 226 KLVVLPLYPQYSISTSGSSIRVLQNIVKEDPYFAGLPISIIESWYQREGYVKSMADLIEK 285 Query: 184 KLTLFPAGVRDQVLILFTAHSLPLKAVS-RGDTYPHEVAASVSATVSEL---GAVNPHRL 351 +L++F ++V+I F+AH +PL V GD Y ++ ++ + EL G +N H L Sbjct: 286 ELSVFSNP--EEVMIFFSAHGVPLTYVKDAGDPYRDQMEDCIALIMEELKSRGTLNDHTL 343 Query: 352 VWQSKVGPLPWLQPYTDDAIKSYAKQGVKYMILVPIAFVNEHIETLHELDIEYCDEVAKE 531 +QS+VGP+ WL+PYTD+ + ++GVK ++ VP++FV+EHIETL E+D+EY E+A E Sbjct: 344 AYQSRVGPVQWLKPYTDEVLVELGQKGVKSLLAVPVSFVSEHIETLEEIDMEY-RELALE 402 Query: 532 AGI 540 +GI Sbjct: 403 SGI 405 >UniRef50_Q747F5 Cluster: Ferrochelatase; n=7; Desulfuromonadales|Rep: Ferrochelatase - Geobacter sulfurreducens Length = 317 Score = 132 bits (318), Expect = 8e-30 Identities = 68/175 (38%), Positives = 101/175 (57%) Frame = +1 Query: 4 RVVIFSQYPQYSCATTGSSLNAVADYYKNKQIPRDIRFSLIERWGSHPLLARVFAERIKE 183 RV+ S YP YS ATTGSS+N + + + + ++R+ HPL AE+I+E Sbjct: 117 RVIALSLYPHYSRATTGSSVNELKRVLSQSGVQFQMMY--VDRFFDHPLYIDALAEKIRE 174 Query: 184 KLTLFPAGVRDQVLILFTAHSLPLKAVSRGDTYPHEVAASVSATVSELGAVNPHRLVWQS 363 L F +V +LF+AHSLP + GD Y + +V + V H L +QS Sbjct: 175 GLDDFHPLA--EVQVLFSAHSLPQSFIDEGDPYLDHIRETVRLVMERFEGVT-HHLAFQS 231 Query: 364 KVGPLPWLQPYTDDAIKSYAKQGVKYMILVPIAFVNEHIETLHELDIEYCDEVAK 528 + GP+ WL+P TD+ ++ A VK +++VP++FV++HIETLHE+DIEY E K Sbjct: 232 RAGPVKWLEPSTDEMLEHLAAHQVKNLLIVPLSFVSDHIETLHEIDIEYAQEAHK 286 >UniRef50_O04921 Cluster: Ferrochelatase-2, chloroplast precursor; n=34; cellular organisms|Rep: Ferrochelatase-2, chloroplast precursor - Arabidopsis thaliana (Mouse-ear cress) Length = 512 Score = 128 bits (310), Expect = 8e-29 Identities = 69/183 (37%), Positives = 111/183 (60%), Gaps = 4/183 (2%) Frame = +1 Query: 4 RVVIFSQYPQYSCATTGSSLNAVADYYKNKQIPRDIRFSLIERWGSHPLLARVFAERIKE 183 ++V+ YPQ+S +T+GSSL + ++ + +++ ++I W + A I+ Sbjct: 218 KLVVLPLYPQFSISTSGSSLRLLERIFREDEYLVNMQHTVIPSWYQREGYIKAMANLIQS 277 Query: 184 KLTLFPAGVRDQVLILFTAHSLPLKAVSR-GDTYPHEVAASVSATVSELGA---VNPHRL 351 +L F G +QV+I F+AH +PL V GD Y E+ V + EL N + L Sbjct: 278 ELGKF--GSPNQVVIFFSAHGVPLAYVEEAGDPYKAEMEECVDLIMEELDKRKITNAYTL 335 Query: 352 VWQSKVGPLPWLQPYTDDAIKSYAKQGVKYMILVPIAFVNEHIETLHELDIEYCDEVAKE 531 +QS+VGP+ WL+PYT++AI K+GV+ ++ VPI+FV+EHIETL E+D+EY E+A + Sbjct: 336 AYQSRVGPVEWLKPYTEEAITELGKKGVENLLAVPISFVSEHIETLEEIDVEY-KELALK 394 Query: 532 AGI 540 +GI Sbjct: 395 SGI 397 >UniRef50_P42044 Cluster: Ferrochelatase-2, chloroplast precursor; n=3; core eudicotyledons|Rep: Ferrochelatase-2, chloroplast precursor - Cucumis sativus (Cucumber) Length = 514 Score = 126 bits (305), Expect = 3e-28 Identities = 65/183 (35%), Positives = 107/183 (58%), Gaps = 4/183 (2%) Frame = +1 Query: 4 RVVIFSQYPQYSCATTGSSLNAVADYYKNKQIPRDIRFSLIERWGSHPLLARVFAERIKE 183 R+V+ YPQYS +TTGSS+ + ++ + S+I+ W + A+ ++ Sbjct: 232 RLVVLPLYPQYSISTTGSSIRVLQKMFREDAYLSSLPVSIIKSWYQREGYIKSMADLMQA 291 Query: 184 KLTLFPAGVRDQVLILFTAHSLPLKAVSR-GDTYPHEVAASVSATVSEL---GAVNPHRL 351 +L F +V+I F+AH +P+ V GD Y ++ + + EL G N H L Sbjct: 292 ELKNFANP--QEVMIFFSAHGVPVSYVENAGDPYKDQMEECICLIMQELKARGIGNEHTL 349 Query: 352 VWQSKVGPLPWLQPYTDDAIKSYAKQGVKYMILVPIAFVNEHIETLHELDIEYCDEVAKE 531 +QS+VGP+ WL+PYTD+ + ++G+K ++ VP++FV+EHIETL E+D+EY +A E Sbjct: 350 AYQSRVGPVQWLKPYTDEVLVELGQKGIKSLLAVPVSFVSEHIETLEEIDMEY-KHLALE 408 Query: 532 AGI 540 +GI Sbjct: 409 SGI 411 >UniRef50_Q9ATG7 Cluster: Ferrochelatase; n=1; Polytomella sp. Pringsheim 198.80|Rep: Ferrochelatase - Polytomella sp. Pringsheim 198.80 Length = 440 Score = 124 bits (300), Expect = 1e-27 Identities = 72/183 (39%), Positives = 106/183 (57%), Gaps = 4/183 (2%) Frame = +1 Query: 4 RVVIFSQYPQYSCATTGSSLNAVADYYKNKQIPRDIRFSLIERWGSHPLLARVFAERIKE 183 ++V YPQYS +TTGSSL + D + + + ++I R+ S P + A+ ++ Sbjct: 180 KLVALPLYPQYSISTTGSSLRCIRDEFNSDPYLSQVPLAVISRFSSRPGYIQSMADLVQL 239 Query: 184 KLTLFPAGVRDQVLILFTAHSLPLKAVSRG-DTYPHEVAASVSATVSEL---GAVNPHRL 351 +L F +V I FTAH +P K V+ D Y E+ VS +++L G N H L Sbjct: 240 ELKKFQNP--SEVHIFFTAHGVPKKYVTDFLDPYQQEMEECVSLIMADLKARGVSNSHLL 297 Query: 352 VWQSKVGPLPWLQPYTDDAIKSYAKQGVKYMILVPIAFVNEHIETLHELDIEYCDEVAKE 531 +QS+VGP WL+PYT +AI + G K ++ VPI+FV+EHIETL E+D EY E+A Sbjct: 298 AYQSRVGPTEWLKPYTSEAIPALGALGCKGLLAVPISFVSEHIETLDEIDEEY-RELALH 356 Query: 532 AGI 540 +GI Sbjct: 357 SGI 359 >UniRef50_A7T926 Cluster: Predicted protein; n=1; Nematostella vectensis|Rep: Predicted protein - Nematostella vectensis Length = 249 Score = 121 bits (291), Expect = 2e-26 Identities = 56/93 (60%), Positives = 67/93 (72%) Frame = +1 Query: 253 LKAVSRGDTYPHEVAASVSATVSELGAVNPHRLVWQSKVGPLPWLQPYTDDAIKSYAKQG 432 L + RGD YP EVAA+V + L + +RLVWQSKVGPLPWL P T+DAIK AK Sbjct: 145 LSRLDRGDPYPQEVAATVQRVMEALDFSHSYRLVWQSKVGPLPWLGPQTEDAIKGLAKNN 204 Query: 433 VKYMILVPIAFVNEHIETLHELDIEYCDEVAKE 531 K ++LVPIAF ++HIETLHELDIEY E+A E Sbjct: 205 KKNLLLVPIAFTSDHIETLHELDIEYAQELAHE 237 >UniRef50_O67083 Cluster: Ferrochelatase; n=1; Aquifex aeolicus|Rep: Ferrochelatase - Aquifex aeolicus Length = 309 Score = 120 bits (289), Expect = 3e-26 Identities = 70/187 (37%), Positives = 106/187 (56%), Gaps = 1/187 (0%) Frame = +1 Query: 7 VVIFSQYPQYSCATTGSSLNAVADYYKNKQIPRD-IRFSLIERWGSHPLLARVFAERIKE 183 V++ YPQYS TTGS+ N K + D I+ IE + HPL + +AE+IK+ Sbjct: 113 VILLPLYPQYSKTTTGSAFNEFER--SKKALKADHIKVKKIEHFYDHPLYIKAWAEQIKQ 170 Query: 184 KLTLFPAGVRDQVLILFTAHSLPLKAVSRGDTYPHEVAASVSATVSELGAVNPHRLVWQS 363 + ++ LF+AHSLP K + GD Y + +V + V + L +QS Sbjct: 171 SVEK-----PEEYHFLFSAHSLPKKLIEEGDPYQEQTEKTVKLIMENFPEVE-YTLAYQS 224 Query: 364 KVGPLPWLQPYTDDAIKSYAKQGVKYMILVPIAFVNEHIETLHELDIEYCDEVAKEAGIV 543 KVG WL+P TD+ I++ K+ VK ++++PI+FV+EH ETL+ELD +Y E+A+E G Sbjct: 225 KVGFGKWLEPSTDEVIRNLIKKEVKKLLVIPISFVSEHSETLYELDKQY-RELAQELGYE 283 Query: 544 QIERAET 564 + R T Sbjct: 284 EFVRVPT 290 >UniRef50_Q2RZ44 Cluster: Ferrochelatase; n=1; Salinibacter ruber DSM 13855|Rep: Ferrochelatase - Salinibacter ruber (strain DSM 13855) Length = 394 Score = 119 bits (286), Expect = 6e-26 Identities = 70/195 (35%), Positives = 108/195 (55%), Gaps = 1/195 (0%) Frame = +1 Query: 1 ERVVIFSQYPQYSCATTGSSLNAVADYYKNKQIPRDIRFSLIERWGSHPLLARVFAERIK 180 ++VV+ YPQYS TTG+SL + K +IP S+ E + ++P ++RI Sbjct: 135 DKVVLLPLYPQYSKTTTGASLVYWHELEKAGEIPAWPTTSVFE-YATYPKYIEALSDRID 193 Query: 181 EKLTLFPAGVRDQVLILFTAHSLPLKAVS-RGDTYPHEVAASVSATVSELGAVNPHRLVW 357 E L FP VRD V +LF+AH PL + R D Y V ++V + G + + Sbjct: 194 EGLERFPDDVRDDVHLLFSAHGTPLSEMKDRDDPYCCLVHSTVKHLMEHRGFDHDFSTAF 253 Query: 358 QSKVGPLPWLQPYTDDAIKSYAKQGVKYMILVPIAFVNEHIETLHELDIEYCDEVAKEAG 537 QSKVGP WL P TDD ++ A++G + ++++P+AFV +HIET +EL IE +++ +E Sbjct: 254 QSKVGPSEWLTPATDDTVEELAEEG-EDVLVIPVAFVTDHIETSYELAIEIPEDLEEEGA 312 Query: 538 IVQIERAETPEHSSH 582 + P +SH Sbjct: 313 PIPEHYEVMPGLNSH 327 >UniRef50_Q3A6H8 Cluster: Ferrochelatase; n=1; Pelobacter carbinolicus DSM 2380|Rep: Ferrochelatase - Pelobacter carbinolicus (strain DSM 2380 / Gra Bd 1) Length = 352 Score = 117 bits (282), Expect = 2e-25 Identities = 61/187 (32%), Positives = 106/187 (56%), Gaps = 2/187 (1%) Frame = +1 Query: 1 ERVVIFSQYPQYSCATTGSSLNAVADYYKNK-QIPRDIRFSLIERWGSHPLLARVFAERI 177 +R ++ S YP ++ AT+GSS+N D+ ++ + ++ + LI W P A + Sbjct: 128 KRAMVLSLYPHFTAATSGSSIN---DFCRHAVRFCPELDYRLIHDWFDWPPFLDALAHLV 184 Query: 178 KEKLTLFPAGVRDQVLILFTAHSLPLKAVSRGDTYPHEVAASVSATVSELGAVNPH-RLV 354 +E L F R +V +LF+AH+LP K + GD Y +V ++ + L RL Sbjct: 185 REALARFDGEQRHRVTLLFSAHALPEKLILEGDPYLDQVRTTMRGVLERLPEYRSRSRLA 244 Query: 355 WQSKVGPLPWLQPYTDDAIKSYAKQGVKYMILVPIAFVNEHIETLHELDIEYCDEVAKEA 534 +QS+ GP+ W+ P +A+ + +GV+ +++VP++FV++H+ETLHE+D Y D A Sbjct: 245 FQSRSGPVRWIGPSVTEALDTLVDEGVREVLVVPVSFVSDHVETLHEIDQGYRD-YALRR 303 Query: 535 GIVQIER 555 G+ + ER Sbjct: 304 GMTRFER 310 >UniRef50_Q6APB0 Cluster: Ferrochelatase; n=1; Desulfotalea psychrophila|Rep: Ferrochelatase - Desulfotalea psychrophila Length = 320 Score = 116 bits (279), Expect = 4e-25 Identities = 69/180 (38%), Positives = 99/180 (55%) Frame = +1 Query: 1 ERVVIFSQYPQYSCATTGSSLNAVADYYKNKQIPRDIRFSLIERWGSHPLLARVFAERIK 180 ER+V S YP YS ATTGSSL + K K I + + I W A IK Sbjct: 119 ERLVALSLYPHYSKATTGSSLTQLHKTLKKKNI--SLPLTEIPSWPKQRDYIAAIAANIK 176 Query: 181 EKLTLFPAGVRDQVLILFTAHSLPLKAVSRGDTYPHEVAASVSATVSELGAVNPHRLVWQ 360 + L F ++ I+++AHSLP + GD Y S+ A G RL +Q Sbjct: 177 KGLATFHG---EKTEIVYSAHSLPTSFIEAGDPYVEHTKQSIGAIEEITGKRG--RLCFQ 231 Query: 361 SKVGPLPWLQPYTDDAIKSYAKQGVKYMILVPIAFVNEHIETLHELDIEYCDEVAKEAGI 540 SK GP+ WL+P T D + A++GVK +++VPI+FV++H+ETL+E+DI Y + AK+ G+ Sbjct: 232 SKSGPVEWLEPSTPDVLIQLAQEGVKNILMVPISFVSDHVETLYEIDILY-KKQAKKLGM 290 >UniRef50_Q1K4G8 Cluster: Ferrochelatase; n=1; Desulfuromonas acetoxidans DSM 684|Rep: Ferrochelatase - Desulfuromonas acetoxidans DSM 684 Length = 322 Score = 115 bits (276), Expect = 1e-24 Identities = 62/181 (34%), Positives = 105/181 (58%), Gaps = 1/181 (0%) Frame = +1 Query: 1 ERVVIFSQYPQYSCATTGSSLNAVADYYKN-KQIPRDIRFSLIERWGSHPLLARVFAERI 177 + V+ S YP Y+ ATTGSS+ D+ + Q D++ IE W AE + Sbjct: 118 KEAVVVSLYPHYTGATTGSSIK---DFKRAVSQHAPDLQCRYIEEWHDQDQYLDALAECV 174 Query: 178 KEKLTLFPAGVRDQVLILFTAHSLPLKAVSRGDTYPHEVAASVSATVSELGAVNPHRLVW 357 ++ L P R ++ +LF+AH+LP K + RGD Y V +V+ + +G P ++ + Sbjct: 175 QDGLAQVPEAKRGKLTLLFSAHALPQKFIDRGDPYQQHVEETVAGVMERVGDY-PCQIGY 233 Query: 358 QSKVGPLPWLQPYTDDAIKSYAKQGVKYMILVPIAFVNEHIETLHELDIEYCDEVAKEAG 537 QS+ GP+ W+ P T D I + K+ + ++++P++FV++HIETL E+D+E+ D A+E G Sbjct: 234 QSRSGPVKWMSPDTLDLIAAAGKER-RSLLVIPVSFVSDHIETLEEVDVEFRDH-AEEHG 291 Query: 538 I 540 + Sbjct: 292 V 292 >UniRef50_Q6BFD7 Cluster: Ferrochelatase (EC 4.99.1.1), putative; n=1; Paramecium tetraurelia|Rep: Ferrochelatase (EC 4.99.1.1), putative - Paramecium tetraurelia Length = 381 Score = 113 bits (272), Expect = 3e-24 Identities = 63/182 (34%), Positives = 100/182 (54%), Gaps = 5/182 (2%) Frame = +1 Query: 1 ERVVIFSQYPQYSCATTGSSL-NAVADYYKNKQIPRDIRFSLIERWGSHPLLARVFAERI 177 ++ ++FSQYPQYSC+T G+++ NA+ K K I + S+I+ W + A + Sbjct: 141 QKFLLFSQYPQYSCSTGGNAIRNAIELLQKYKTIQPKLEVSVIDSWHKNKFYISAMATLL 200 Query: 178 KEKLTLFPAGVRDQVLILFTAHSLPLKAVSRGDTYPHEVAASVSATVSEL---GAVNPHR 348 K+ +D LILFTAHSLP V G+ YP+ + S + L G Sbjct: 201 NNKIKAQNLDPKD-TLILFTAHSLPADFVWDGEKYPYYIYESCQLVIDNLKNMGVSITFD 259 Query: 349 LVWQSKVGPLPWLQPYTDDAIKSYAKQG-VKYMILVPIAFVNEHIETLHELDIEYCDEVA 525 L +QSKVG WL+P T A+ Y + K +++ P+ F ++H+ETL+ELDI+ +++ Sbjct: 260 LSYQSKVGLNKWLRPATHHALSQYIRNSKFKNILISPMGFTSDHLETLYELDIQLMEDLK 319 Query: 526 KE 531 K+ Sbjct: 320 KD 321 >UniRef50_P57777 Cluster: Ferrochelatase; n=12; Alphaproteobacteria|Rep: Ferrochelatase - Caulobacter crescentus (Caulobacter vibrioides) Length = 347 Score = 109 bits (263), Expect = 4e-23 Identities = 69/179 (38%), Positives = 97/179 (54%) Frame = +1 Query: 1 ERVVIFSQYPQYSCATTGSSLNAVADYYKNKQIPRDIRFSLIERWGSHPLLARVFAERIK 180 ++VV+ YPQ+S TTGSSL A YK + + E G L A I+ Sbjct: 120 DQVVLLPLYPQFSTTTTGSSLKAWKKTYKGSGVQTTVGCYPTE--GG---LIEAHARMIR 174 Query: 181 EKLTLFPAGVRDQVLILFTAHSLPLKAVSRGDTYPHEVAASVSATVSELGAVNPHRLVWQ 360 E AG + +LF+AH LP K + GD Y +V A+ +A + L + +Q Sbjct: 175 ESWE--KAGSPTNIRLLFSAHGLPEKVILAGDPYQKQVEATAAAVAAHLPPQIEWTVCYQ 232 Query: 361 SKVGPLPWLQPYTDDAIKSYAKQGVKYMILVPIAFVNEHIETLHELDIEYCDEVAKEAG 537 S+VGPL W+ P TDD I+ + K +++ PIAFV+EH+ETL ELD EY E+A+E G Sbjct: 233 SRVGPLKWIGPSTDDEIRRAGGED-KGVMITPIAFVSEHVETLVELDHEYA-ELAEEVG 289 >UniRef50_Q4UJN9 Cluster: Ferrochelatase; n=16; Rickettsiales|Rep: Ferrochelatase - Rickettsia felis (Rickettsia azadi) Length = 344 Score = 107 bits (257), Expect = 2e-22 Identities = 67/169 (39%), Positives = 96/169 (56%), Gaps = 1/169 (0%) Frame = +1 Query: 7 VVIFSQYPQYSCATTGSSLNAVADYYKNKQIPRDIRFSLIERWGSHPLLARVFAERIKEK 186 +++ YPQ+S TTGSS V ++ +N I DI I + + IKEK Sbjct: 121 IILLPLYPQFSSTTTGSS---VKNFLQNFDI--DISIKTICCYPQEEDFIKSHVSLIKEK 175 Query: 187 LTLFPAGVRDQVLILFTAHSLPLKAVSRGDTYPHEVAASVSATVSELGAVN-PHRLVWQS 363 L R ILF+AH LP K + GD Y ++ +V A V EL + +++ +QS Sbjct: 176 LYDDDKNFR----ILFSAHGLPEKIIKAGDPYSFQIKETVKAIVKELNIKDLDYKITYQS 231 Query: 364 KVGPLPWLQPYTDDAIKSYAKQGVKYMILVPIAFVNEHIETLHELDIEY 510 +VGP+ WL+P T+D I+ K K +I+VPI+FV+EH+ETL ELDIEY Sbjct: 232 RVGPIEWLKPNTEDEIELAGKLK-KDIIIVPISFVSEHVETLVELDIEY 279 >UniRef50_Q2RN84 Cluster: Ferrochelatase; n=2; Alphaproteobacteria|Rep: Ferrochelatase - Rhodospirillum rubrum (strain ATCC 11170 / NCIB 8255) Length = 362 Score = 107 bits (256), Expect = 3e-22 Identities = 71/200 (35%), Positives = 112/200 (56%), Gaps = 5/200 (2%) Frame = +1 Query: 1 ERVVIFSQYPQYSCATTGSSLNAVADYYKNKQIPRDIRFSLIERWGSHPLLARVFAERIK 180 ++VV+ YPQ+S T+GSSLN + ++ + + + + L AER Sbjct: 117 DQVVLLPLYPQFSGTTSGSSLNQWT--VEAEKAGLTAQTHTVCCYATEVGLITALAERTL 174 Query: 181 ---EKLTLFPAGVRDQVLILFTAHSLPLKAVSRGDTYPHEVAASVSATVSELGAVN-PHR 348 E++ G+ +LF+AH LP K V GD Y V A+V+A V+ + ++ Sbjct: 175 GGLEQVRESTVGL-PAPRVLFSAHGLPRKVVDAGDPYQSHVEATVNAVVAAMAVEGLDYQ 233 Query: 349 LVWQSKVGPLPWLQPYTDDAIKSYAKQGVKYMILVPIAFVNEHIETLHELDIEYCDEVAK 528 + +QS+VGPL W+ P T+D I ++G + +++VP+AFV+EH ETL ELDIEY E+A+ Sbjct: 234 VCYQSRVGPLEWIGPSTEDEIAKAGREG-RPLVVVPVAFVSEHSETLVELDIEY-GELAE 291 Query: 529 EAGIVQIERAET-PEHSSHI 585 E G+ + R T EH + I Sbjct: 292 ERGVPKYVRVPTVREHPAFI 311 >UniRef50_A7H9E2 Cluster: Ferrochelatase; n=2; Anaeromyxobacter|Rep: Ferrochelatase - Anaeromyxobacter sp. Fw109-5 Length = 319 Score = 107 bits (256), Expect = 3e-22 Identities = 65/179 (36%), Positives = 97/179 (54%) Frame = +1 Query: 4 RVVIFSQYPQYSCATTGSSLNAVADYYKNKQIPRDIRFSLIERWGSHPLLARVFAERIKE 183 R V YPQY+ ATT SSL + + P ++ + I W H A ++E Sbjct: 116 RAVALPLYPQYANATTRSSLVELRRVW-----PGELPLAEICTWHDHEGYLDASAAALRE 170 Query: 184 KLTLFPAGVRDQVLILFTAHSLPLKAVSRGDTYPHEVAASVSATVSELGAVNPHRLVWQS 363 L PA R L++F+AH LP+ V +GD YP + S T GA R+ +QS Sbjct: 171 TLEALPASDRASALVVFSAHGLPMSQVRKGDPYPGYIEHSARETARRAGA-QEFRVTYQS 229 Query: 364 KVGPLPWLQPYTDDAIKSYAKQGVKYMILVPIAFVNEHIETLHELDIEYCDEVAKEAGI 540 +VGP WL P T + +++ A+ + ++ VPIAFV+EH+ETL++LD+ +AKEA + Sbjct: 230 RVGPAKWLGPDTVEFLEANARG--RAVVTVPIAFVSEHLETLYDLDV-----LAKEAAL 281 >UniRef50_Q7VD58 Cluster: Ferrochelatase; n=20; Cyanobacteria|Rep: Ferrochelatase - Prochlorococcus marinus Length = 391 Score = 106 bits (255), Expect = 4e-22 Identities = 63/190 (33%), Positives = 101/190 (53%), Gaps = 5/190 (2%) Frame = +1 Query: 7 VVIFSQYPQYSCATTGSSLNAVADYYKNKQIPRDIRFSLIERWGSHPLLARVFAERIKEK 186 VV+ YP +S +T+GSS + + + + + I W + AE I+++ Sbjct: 120 VVVLPLYPHFSISTSGSSFRELRRLREVDKEFQKLSIRCIRSWFDNTGYIASMAELIEQE 179 Query: 187 LTLFPAGVRDQVLILFTAHSLPLKAVSR-GDTYPHEVAASVSATVSE----LGAVNPHRL 351 ++ + + I FTAH +P V GD Y E+ + + LG N + L Sbjct: 180 ISSCESP--NAAHICFTAHGVPKSYVEEAGDPYKDEIQDCALLIIDKVEKSLGFSNSYTL 237 Query: 352 VWQSKVGPLPWLQPYTDDAIKSYAKQGVKYMILVPIAFVNEHIETLHELDIEYCDEVAKE 531 +QS+VGP WL+PYT++ ++ GVK +I+VPI+FV+EHIETL E+DIEY ++A Sbjct: 238 SYQSRVGPEEWLKPYTEEVLEELGANGVKELIVVPISFVSEHIETLQEIDIEY-KKIALN 296 Query: 532 AGIVQIERAE 561 GI+ R + Sbjct: 297 NGIINFRRVK 306 >UniRef50_Q1V1A3 Cluster: Ferrochelatase; n=2; Candidatus Pelagibacter ubique|Rep: Ferrochelatase - Candidatus Pelagibacter ubique HTCC1002 Length = 344 Score = 104 bits (250), Expect = 1e-21 Identities = 69/180 (38%), Positives = 99/180 (55%), Gaps = 1/180 (0%) Frame = +1 Query: 1 ERVVIFSQYPQYSCATTGSSLNAVADYYKNKQIPRDIRFSLIERWGSHPLLARVFAERIK 180 E +++ YPQYS AT+GSS+ D K ++ + I + + + I Sbjct: 118 EEIILMPLYPQYSAATSGSSIKEWRDVCKKNNY--HVKTNTICCYPTDQNFINAHTKEII 175 Query: 181 EKLTLFPAGVRDQVLILFTAHSLPLKAVSRGDTYPHEVAASVSATVSELGAVN-PHRLVW 357 +K+ +++ LI F+AH LP K + +GD Y +V SV V L N L + Sbjct: 176 KKI----KDLKNFKLI-FSAHGLPEKNIKKGDPYQWQVEQSVKKIVENLNIENLDWILSY 230 Query: 358 QSKVGPLPWLQPYTDDAIKSYAKQGVKYMILVPIAFVNEHIETLHELDIEYCDEVAKEAG 537 QS+VGPL W+ P T+D I +K G K+++LVPIAFV+EH ETL ELDIEY E+A G Sbjct: 231 QSRVGPLKWIGPSTEDIIIENSKLG-KHIVLVPIAFVSEHSETLVELDIEY-KEIADANG 288 >UniRef50_Q1NMT4 Cluster: Ferrochelatase; n=2; delta proteobacterium MLMS-1|Rep: Ferrochelatase - delta proteobacterium MLMS-1 Length = 388 Score = 104 bits (250), Expect = 1e-21 Identities = 60/174 (34%), Positives = 98/174 (56%), Gaps = 2/174 (1%) Frame = +1 Query: 25 YPQYSCATTGSSLNAVADYYKNKQIPRDIRFSL--IERWGSHPLLARVFAERIKEKLTLF 198 YP +S ATTGSSLN + + D F+ I W + P +E I++ F Sbjct: 196 YPHFSRATTGSSLNDL----RRALATHDDFFTCREINAWPAQPDYLAALSETIEQGAAAF 251 Query: 199 PAGVRDQVLILFTAHSLPLKAVSRGDTYPHEVAASVSATVSELGAVNPHRLVWQSKVGPL 378 ++ +L++AHSLP+ + GD Y + +++ + LG L +QS+ GP+ Sbjct: 252 GT---EEYTLLYSAHSLPVSFIEDGDPYLEHIKKTIAGLEARLGRSG--ELCFQSRSGPV 306 Query: 379 PWLQPYTDDAIKSYAKQGVKYMILVPIAFVNEHIETLHELDIEYCDEVAKEAGI 540 WL P T + + A +GVK ++LVPI+FV++H+ETL+E+D++Y E+A+ GI Sbjct: 307 RWLSPSTPEMLAQLAGRGVKNVLLVPISFVSDHVETLYEIDLQY-HELARGLGI 359 >UniRef50_A3EV75 Cluster: Protoheme ferro-lyase; n=1; Leptospirillum sp. Group II UBA|Rep: Protoheme ferro-lyase - Leptospirillum sp. Group II UBA Length = 356 Score = 104 bits (250), Expect = 1e-21 Identities = 72/203 (35%), Positives = 110/203 (54%), Gaps = 8/203 (3%) Frame = +1 Query: 7 VVIFSQYPQYSCATTGSSLN-AVADYYKNKQIPRDIRFSLIERWGSHPLLARVFAERIKE 183 +V YPQ S TTGSS A+A+ K+I + I W +P + AE + + Sbjct: 130 LVFLPLYPQRSRTTTGSSFREALAEA---KRIAPGLPVRTIPAWPVYPPYIKSLAETVGD 186 Query: 184 KLTLFPAGVRDQVLILFTAHSLPLKAVSRG-DTYPHEVAASVSATVSELGAVNP-----H 345 L+ P + V ILF+AH +P V+R D Y + A+VSA + L +P H Sbjct: 187 ALSRIPE--EETVHILFSAHGIPEFLVTREKDPYEADTNATVSAAMEALQKFHPQRKLLH 244 Query: 346 RLVWQSKVGPLPWLQPYTDDAIKSYAKQGVKYMILVPIAFVNEHIETLHELDIEYCDEVA 525 L +QS+VGPL WL P T + A +GV+++++VPI+FV++H ETL+E+DI Y ++ Sbjct: 245 HLSYQSRVGPLKWLGPETRLELSRLAGEGVRHLVMVPISFVSDHQETLYEMDILY-GQMT 303 Query: 526 KEAGIVQIERAET-PEHSSHIHS 591 ++ G RA + S IH+ Sbjct: 304 RDLGYKTFLRAPSLNTRPSFIHA 326 >UniRef50_Q2S1S2 Cluster: Ferrochelatase; n=1; Salinibacter ruber DSM 13855|Rep: Ferrochelatase - Salinibacter ruber (strain DSM 13855) Length = 447 Score = 103 bits (248), Expect = 3e-21 Identities = 61/185 (32%), Positives = 97/185 (52%), Gaps = 1/185 (0%) Frame = +1 Query: 1 ERVVIFSQYPQYSCATTGSSLNAVADYYKNKQIPRDIRFSLIERWGSHPLLARVFAERIK 180 ++VV+ YPQY+ TTGS+L + P +++ + ++P + +ERI Sbjct: 155 DKVVLVPSYPQYAAGTTGSALAYWKALGARGERP-SWPTTVVPEYAANPKYVQAVSERID 213 Query: 181 EKLTLFPAGVRDQVLILFTAHSLPLKAVS-RGDTYPHEVAASVSATVSELGAVNPHRLVW 357 E L FP VR++V ++F+AH A R Y V ++V + G P R + Sbjct: 214 EALQRFPRHVREEVALVFSAHGSVFDAQGPRKPPYCCHVHSTVDRVMQHRGRDRPFRTAF 273 Query: 358 QSKVGPLPWLQPYTDDAIKSYAKQGVKYMILVPIAFVNEHIETLHELDIEYCDEVAKEAG 537 QS +GP WL P T D I + A+QG + +++VPIAFV +H+ ++LD++ E A G Sbjct: 274 QSLMGPNHWLTPSTPDTIAALAEQGHRAVLVVPIAFVTDHVNVRYDLDVD-VRETASAHG 332 Query: 538 IVQIE 552 I E Sbjct: 333 IDYFE 337 >UniRef50_Q833G5 Cluster: Ferrochelatase; n=1; Enterococcus faecalis|Rep: Ferrochelatase - Enterococcus faecalis (Streptococcus faecalis) Length = 313 Score = 99.5 bits (237), Expect = 5e-20 Identities = 55/169 (32%), Positives = 90/169 (53%) Frame = +1 Query: 1 ERVVIFSQYPQYSCATTGSSLNAVADYYKNKQIPRDIRFSLIERWGSHPLLARVFAERIK 180 E + + YPQYS T GS ++V +Y+ DI+F I + ++P F+++I Sbjct: 118 EELNVIPMYPQYSGTTVGSVFDSVMNYFIKSDRIVDIKF--IRSFYNNPQYIDYFSKKIN 175 Query: 181 EKLTLFPAGVRDQVLILFTAHSLPLKAVSRGDTYPHEVAASVSATVSELGAVNPHRLVWQ 360 E L P I+F+ H +P+ V GD YP E + + +LG + ++ +Q Sbjct: 176 EALNESPIDA-----IVFSYHGIPMSYVKDGDNYPKECTKTTKLIMDKLGDIRYYQ-TYQ 229 Query: 361 SKVGPLPWLQPYTDDAIKSYAKQGVKYMILVPIAFVNEHIETLHELDIE 507 SK GP WL+P TDD +K +G+K +++V FV + +ET+ EL+ E Sbjct: 230 SKFGPSEWLKPATDDTLKKLPSKGIKNILIVAPGFVVDCLETIEELEHE 278 >UniRef50_A5UU36 Cluster: Ferrochelatase; n=3; Chloroflexi (class)|Rep: Ferrochelatase - Roseiflexus sp. RS-1 Length = 313 Score = 99.1 bits (236), Expect = 7e-20 Identities = 63/188 (33%), Positives = 95/188 (50%), Gaps = 1/188 (0%) Frame = +1 Query: 7 VVIFSQYPQYSCATTGSSLNAVADYYKNKQIPRDIRFSLIERWGSHPLLARVFAERIKEK 186 VV P YS + G V + N + + ++ + IERW HP R+ A+RI Sbjct: 109 VVALVLAPHYSRMSVGGYRRYVDE--ANATLEQPLQITFIERWHDHPGFRRLIADRIVAA 166 Query: 187 LTLFPAGVRDQVLILFTAHSLPLKAVSRGDTYPHEVAASVSATVSELGAVNPHRLVWQSK 366 P + DQ L+LF+AHSLP + +S D YP E+ S + LG + RL +QS Sbjct: 167 RAELPPDLHDQALVLFSAHSLPERILSWNDPYPDELRESAAGIAGLLG-LTDWRLCYQSA 225 Query: 367 -VGPLPWLQPYTDDAIKSYAKQGVKYMILVPIAFVNEHIETLHELDIEYCDEVAKEAGIV 543 + PWL P D ++ +GV+ +I P FV +H+E L ++D E D+ A E G + Sbjct: 226 GMTGEPWLGPDILDYLEELHSEGVRAVISAPFGFVADHLEVLWDIDREAQDKAA-ELG-M 283 Query: 544 QIERAETP 567 ++ R P Sbjct: 284 ELRRIRMP 291 >UniRef50_Q5PA48 Cluster: Ferrochelatase; n=2; Anaplasma|Rep: Ferrochelatase - Anaplasma marginale (strain St. Maries) Length = 350 Score = 98.7 bits (235), Expect = 1e-19 Identities = 64/171 (37%), Positives = 89/171 (52%), Gaps = 1/171 (0%) Frame = +1 Query: 1 ERVVIFSQYPQYSCATTGSSLNAVADYYKNKQIPRDIRFSLIERWGSHPLLARVFAERIK 180 E VV+ YPQYS TT S++ + + D R +I + +H + I Sbjct: 124 EHVVLLPMYPQYSSTTTLSAIEDWNNSARKACYAPDTR--IICCYHTHKDYIAAHCKLIL 181 Query: 181 EKLTLFPAGVRDQVLILFTAHSLPLKAVSRGDTYPHEVAASVSATVSELG-AVNPHRLVW 357 ++ G ILF+AH LP+ V RGD Y ++ SV A V +LG + + + Sbjct: 182 DEYNKAAMG-HSSPRILFSAHGLPVHIVKRGDPYQEQIRQSVCAIVEQLGIRALDYSICY 240 Query: 358 QSKVGPLPWLQPYTDDAIKSYAKQGVKYMILVPIAFVNEHIETLHELDIEY 510 QSKVGP WL+P T I GV +++VPI+FV+EH ETL ELDIEY Sbjct: 241 QSKVGPTQWLEPSTQLEILRAKDDGVP-VVVVPISFVSEHSETLVELDIEY 290 >UniRef50_Q5YU18 Cluster: Ferrochelatase; n=14; Bacteria|Rep: Ferrochelatase - Nocardia farcinica Length = 352 Score = 97.5 bits (232), Expect = 2e-19 Identities = 56/157 (35%), Positives = 88/157 (56%), Gaps = 9/157 (5%) Frame = +1 Query: 124 IERWGSHPLLARVFAERIKEKLTLFPAGVRDQVLILFTAHSLPLKA-------VSRGDTY 282 + ++ HPLL FA+ I+ L PA RD+ ++FTAHS+P+ A G+ Y Sbjct: 142 LRQYFDHPLLIEAFADAIRAALERLPADRRDRARLVFTAHSVPVAADAAAGPPADGGELY 201 Query: 283 PHEVAASVSATVSELGAVNPHRLVWQSKVGP--LPWLQPYTDDAIKSYAKQGVKYMILVP 456 +VA + + G + H LVWQS+ GP +PWL+P D ++ A +GV +++ P Sbjct: 202 SRQVADAARLCAAATGFAD-HDLVWQSRSGPPQVPWLEPDIVDHLEDLAGRGVDAVVVCP 260 Query: 457 IAFVNEHIETLHELDIEYCDEVAKEAGIVQIERAETP 567 + FV++H+E + +LD E D+ A E G+ RA TP Sbjct: 261 VGFVSDHLEVIWDLDNEAKDKAA-ELGMA-FARASTP 295 >UniRef50_Q5DEU6 Cluster: SJCHGC05531 protein; n=1; Schistosoma japonicum|Rep: SJCHGC05531 protein - Schistosoma japonicum (Blood fluke) Length = 152 Score = 95.9 bits (228), Expect = 7e-19 Identities = 38/75 (50%), Positives = 57/75 (76%) Frame = +1 Query: 340 PHRLVWQSKVGPLPWLQPYTDDAIKSYAKQGVKYMILVPIAFVNEHIETLHELDIEYCDE 519 P+RL WQSKVGP WL P T D++ ++ G ++ IL+P+AF +HIETL+E+D+EYC E Sbjct: 9 PYRLTWQSKVGPAAWLGPSTADSLYGLSRLGYRHAILIPVAFTLDHIETLYEMDVEYCTE 68 Query: 520 VAKEAGIVQIERAET 564 VA +AG+V + R+++ Sbjct: 69 VASKAGMVTVRRSQS 83 >UniRef50_P56107 Cluster: Ferrochelatase; n=5; Helicobacteraceae|Rep: Ferrochelatase - Helicobacter pylori (Campylobacter pylori) Length = 334 Score = 94.3 bits (224), Expect = 2e-18 Identities = 63/174 (36%), Positives = 95/174 (54%), Gaps = 4/174 (2%) Frame = +1 Query: 1 ERVVIFSQYPQYSCATTGSSLNAVADYYKNKQIPRDIRFSLIERWGSHPLLARVFAERIK 180 E +V FS YPQYS TT SS N + K+ + R + +IER+ + L ++ I Sbjct: 131 ESLVFFSMYPQYSSTTTLSSFNDAFNALKSLETFRP-KVRVIERFYASKKLNKIILNTIL 189 Query: 181 EKLTLFPAGVRDQVLILFTAHSLPLKAVSRGDTYPHEVAASVSATVSELGAVN-PHR--- 348 TL +D VLI F+ H LP + GDTY E VS + N P + Sbjct: 190 N--TLNNRKSQDFVLI-FSVHGLPKSVIDAGDTYQQECEHHVSLLKELMQQKNTPFKEVL 246 Query: 349 LVWQSKVGPLPWLQPYTDDAIKSYAKQGVKYMILVPIAFVNEHIETLHELDIEY 510 L +QSK+GP+ WL+P T++ I+ + K ++I+ P+AF ++ ETL+ELD++Y Sbjct: 247 LSYQSKLGPMKWLEPSTEELIEKHRK---SHIIIYPLAFTIDNSETLYELDMQY 297 >UniRef50_Q5GRR7 Cluster: Ferrochelatase; n=1; Wolbachia endosymbiont strain TRS of Brugia malayi|Rep: Ferrochelatase - Wolbachia sp. subsp. Brugia malayi (strain TRS) Length = 340 Score = 93.9 bits (223), Expect = 3e-18 Identities = 59/172 (34%), Positives = 92/172 (53%), Gaps = 2/172 (1%) Frame = +1 Query: 1 ERVVIFSQYPQYSCATTGSSLNAVADYYKN-KQIPRDIRFSLIERWGSHPLLARVFAERI 177 + V++ YPQYS TT L+++ ++ KN KQ +I + A I Sbjct: 142 DEVILLPLYPQYSTTTT---LSSIENWQKNAKQYGIKCNTKIIRHHYDNQDFIEAHANLI 198 Query: 178 KEKLTLFPAGVRDQVLILFTAHSLPLKAVSRGDTYPHEVAASVSATVSELGAVN-PHRLV 354 + L A + +LF+AHSLPL + +GD Y +V +V V +L + + Sbjct: 199 TKHYKL--ASEVGKPRVLFSAHSLPLSVIKKGDPYALQVEETVKLIVKKLHIKDLDWSIC 256 Query: 355 WQSKVGPLPWLQPYTDDAIKSYAKQGVKYMILVPIAFVNEHIETLHELDIEY 510 +QSK+GP+ WL+P T+ + GV ++L+PI+FV+EH ETL ELD+EY Sbjct: 257 YQSKIGPVKWLEPSTESELLRAKADGVP-VVLLPISFVSEHSETLVELDMEY 307 >UniRef50_Q8FTB1 Cluster: Ferrochelatase; n=24; Actinomycetales|Rep: Ferrochelatase - Corynebacterium efficiens Length = 377 Score = 91.9 bits (218), Expect = 1e-17 Identities = 51/162 (31%), Positives = 88/162 (54%), Gaps = 9/162 (5%) Frame = +1 Query: 106 DIRFSLIERWGSHPLLARVFAERIKEKLTLFPAGVRDQVLILFTAHSLPLKAVSR----- 270 ++ F+ + ++ HP R A+ ++E P +RD+ ++FTAHS+PL + Sbjct: 149 EVTFTKLRQFYDHPRFVRTMAQYVRESFDKLPEDLRDEARLVFTAHSIPLNSKDADGNPI 208 Query: 271 -GDTYPHEVAASVSATVSELGAVNPHRLVWQSKVGP--LPWLQP-YTDDAIKSYAKQGVK 438 G Y +V S SA ++ ++ +VWQS+ G +PWL+P D A++ G K Sbjct: 209 DGSIYSRQVEES-SALIAREAGIDDFDVVWQSRSGSPHVPWLEPDIVDHAVELNENNGQK 267 Query: 439 YMILVPIAFVNEHIETLHELDIEYCDEVAKEAGIVQIERAET 564 +++ P+ F+++H+E + +LD E DE A G+V IER T Sbjct: 268 ALVVCPVGFISDHMEVIWDLDSELMDE-ATRRGMV-IERVAT 307 >UniRef50_Q2GH68 Cluster: Ferrochelatase; n=3; canis group|Rep: Ferrochelatase - Ehrlichia chaffeensis (strain Arkansas) Length = 343 Score = 91.5 bits (217), Expect = 1e-17 Identities = 64/179 (35%), Positives = 97/179 (54%), Gaps = 2/179 (1%) Frame = +1 Query: 1 ERVVIFSQYPQYSCATTGSSLNAVADY-YKNKQIPRDIRFSLIERWGSHPLLARVFAERI 177 +++++ YP YS TT L+A+ + Y K+ S I + ++ + + I Sbjct: 124 DKIILIPLYPHYSTTTT---LSAIQHWNYHMKKSRFHCPTSTICCYYNNENYIKAHCQLI 180 Query: 178 KEKLTLFPAGVRDQVLILFTAHSLPLKAVSRGDTYPHEVAASVSATVSELGAVN-PHRLV 354 EK A ILF+AHSLPL V RGD Y H++ +V L + +++ Sbjct: 181 IEKYR--EAQNYGSPRILFSAHSLPLSIVQRGDPYQHQIEQTVLLITKSLNISSLDYKIC 238 Query: 355 WQSKVGPLPWLQPYTDDAIKSYAKQGVKYMILVPIAFVNEHIETLHELDIEYCDEVAKE 531 +QSKVG + WL+P T AI + AKQ ++LVPI+FV+E+ ETL ELDIE ++KE Sbjct: 239 YQSKVGNIKWLEPSTISAI-NQAKQDDVPIVLVPISFVSENSETLVELDIECKKIISKE 296 >UniRef50_Q0BWA5 Cluster: Ferrochelatase; n=1; Hyphomonas neptunium ATCC 15444|Rep: Ferrochelatase - Hyphomonas neptunium (strain ATCC 15444) Length = 357 Score = 89.8 bits (213), Expect = 4e-17 Identities = 64/188 (34%), Positives = 93/188 (49%), Gaps = 1/188 (0%) Frame = +1 Query: 1 ERVVIFSQYPQYSCATTGSSLNAVADYYKNKQIPRDIRFSLIERWGSHPLLARVFAERIK 180 + VV+ YPQ+S TTGSSL+A YK K R I +P + + Sbjct: 122 DEVVLLPLYPQFSTTTTGSSLSAWHKAYKGKS--RTIC--------CYPFEENFVSAHVD 171 Query: 181 EKLTLFP-AGVRDQVLILFTAHSLPLKAVSRGDTYPHEVAASVSATVSELGAVNPHRLVW 357 + + + AG V +L +AH LP V GD Y + A + A + + Sbjct: 172 QIMAAWERAGRPGNVNLLLSAHGLPESVVKSGDPYQWQCEALAEMIAGRVPADWEVSVCY 231 Query: 358 QSKVGPLPWLQPYTDDAIKSYAKQGVKYMILVPIAFVNEHIETLHELDIEYCDEVAKEAG 537 QS+VGP+ W+ P T++ I + QG + +++ PIAFV+EHIETL EL EY VA++ G Sbjct: 232 QSRVGPMKWIGPPTEEEIARISDQG-RNILIAPIAFVSEHIETLVELGEEY-RLVAEKHG 289 Query: 538 IVQIERAE 561 R E Sbjct: 290 AASYTRVE 297 >UniRef50_A6Q2Y9 Cluster: Ferrochelatase; n=2; Epsilonproteobacteria|Rep: Ferrochelatase - Nitratiruptor sp. (strain SB155-2) Length = 309 Score = 89.8 bits (213), Expect = 4e-17 Identities = 65/192 (33%), Positives = 101/192 (52%), Gaps = 2/192 (1%) Frame = +1 Query: 7 VVIFSQYPQYSCATTGSSLNAVADYYKN-KQIPRDIRFSLIERWGSHPLLARVFAERIKE 183 V + YP YS TT SSL D+Y K + RF I + + L + ERI+E Sbjct: 114 VFLIPLYPHYSTTTTKSSLE---DFYNMAKGVGYHARFHDIANFYENRLYNQAIIERIEE 170 Query: 184 KLTLFPAGVRDQVLILFTAHSLPLKAVSRGDTYPHEVAASVSATVSEL-GAVNPHRLVWQ 360 L ++ L+ F+AHSLP K + +GD Y EV V S L + + L +Q Sbjct: 171 ALD--GEDTKEYELV-FSAHSLPQKIIEKGDPYLQEVQEHVKILTSILEEKFSGYHLAFQ 227 Query: 361 SKVGPLPWLQPYTDDAIKSYAKQGVKYMILVPIAFVNEHIETLHELDIEYCDEVAKEAGI 540 SK+GP+ WL+P D+ ++ +G K +++ PI+F ++ ET EL IEY ++A++ G+ Sbjct: 228 SKLGPVKWLEPGLDEKLEEL--KG-KKILVYPISFTLDNSETEFELHIEYA-QIAQKIGV 283 Query: 541 VQIERAETPEHS 576 + + A P S Sbjct: 284 KKYKVARCPNES 295 >UniRef50_Q9RV98 Cluster: Ferrochelatase; n=1; Deinococcus radiodurans|Rep: Ferrochelatase - Deinococcus radiodurans Length = 316 Score = 87.0 bits (206), Expect = 3e-16 Identities = 49/183 (26%), Positives = 88/183 (48%), Gaps = 2/183 (1%) Frame = +1 Query: 7 VVIFSQYPQYSCATTGSSLNAVADYYKNKQIPRDIRFSLIERWGSHPLLARVFAERIKEK 186 +V+ QY S A + A + I F+ I+ + + P A+R++ Sbjct: 113 IVLAPQYSSLSVAKYQKKIKAALEMNHGH-----IDFAYIDNYHTEPGYITALADRVRIG 167 Query: 187 LTLFPAGVRDQVLILFTAHSLPLKAVSRGDTYPHEVAASVSATVSELGAVNPHRLVWQSK 366 + FP RD V ++ +AHSLP++ + GD Y ++ + ++ G + Sbjct: 168 IQEFPEDERDDVHVILSAHSLPVRIIKEGDPYADQLHETARLVAAQAGLTDEQWSWSYQS 227 Query: 367 VG--PLPWLQPYTDDAIKSYAKQGVKYMILVPIAFVNEHIETLHELDIEYCDEVAKEAGI 540 G P PWL P D+ ++ +QG+K ++ + I FV++H+E L ++DI EVA E G+ Sbjct: 228 AGRSPEPWLGPQLDEHLRDLNEQGIKKVVSIAIGFVSDHVEILFDIDIA-AQEVAHELGM 286 Query: 541 VQI 549 + Sbjct: 287 TLV 289 >UniRef50_P43868 Cluster: Ferrochelatase; n=40; Bacteria|Rep: Ferrochelatase - Haemophilus influenzae Length = 323 Score = 86.2 bits (204), Expect = 5e-16 Identities = 53/180 (29%), Positives = 89/180 (49%), Gaps = 1/180 (0%) Frame = +1 Query: 1 ERVVIFSQYPQYSCATTGSSLNAVADYYKNKQIPRDIRFSLIERWGSHPLLARVFAERIK 180 ER+++ YPQYS +TTG+ +A A+ K ++ + F I + A+ IK Sbjct: 125 ERIIVLPLYPQYSSSTTGAVFDAFANALKEER--GLLPFDFIHSYHIDENYINALADSIK 182 Query: 181 EKLTLFPAGVRDQVLILFTAHSLPLKAVSRGDTYPHEVAASVSATVSELGAV-NPHRLVW 357 +L + +LF+ H +PL+ GD Y + A V++LG N R+ + Sbjct: 183 VRL-------KSDEFLLFSYHGIPLRYEKMGDYYREHCKQTTIAVVNKLGLTENQWRMTF 235 Query: 358 QSKVGPLPWLQPYTDDAIKSYAKQGVKYMILVPIAFVNEHIETLHELDIEYCDEVAKEAG 537 QS+ G WLQPYTD ++S A Q ++ + ++ F + +ET+ E+D E + G Sbjct: 236 QSRFGREEWLQPYTDKFLESAAAQNIQKIAVICPGFSVDCLETIEEIDEENRENFLNNGG 295 >UniRef50_Q2BIY0 Cluster: Ferrochelatase; n=2; Gammaproteobacteria|Rep: Ferrochelatase - Neptuniibacter caesariensis Length = 336 Score = 85.0 bits (201), Expect = 1e-15 Identities = 52/180 (28%), Positives = 89/180 (49%), Gaps = 1/180 (0%) Frame = +1 Query: 1 ERVVIFSQYPQYSCATTGSSLNAVADYYKNKQIPRDIRFSLIERWGSHPLLARVFAERIK 180 E+V++ YPQYS TT + VA + ++ D+R ++ + HP + E + Sbjct: 129 EKVLLIPMYPQYSATTTAPVYDQVAKFQLQQRRVLDVR--IVNSYYDHPK----YVEALA 182 Query: 181 EKLTLFPAGVRDQVLILFTAHSLPLKAVSRGDTYPHEVAASVSATVSELGAVNPHRLV-W 357 ++ F A ++ + H +P + +GD YP + + +LG + + + Sbjct: 183 NQVANFRAENESVDKLILSYHGIPKEYADKGDPYPLQCHKTSELLAEKLGLADTEWMTTF 242 Query: 358 QSKVGPLPWLQPYTDDAIKSYAKQGVKYMILVPIAFVNEHIETLHELDIEYCDEVAKEAG 537 QS+ GP WLQPYTD ++ +QGVK + + AF + +ETL E+ E EV +AG Sbjct: 243 QSRFGPAEWLQPYTDKTLEKLPEQGVKKLQIACPAFSADCLETLEEI-AEENREVFMDAG 301 >UniRef50_P43413 Cluster: Ferrochelatase; n=28; Gammaproteobacteria|Rep: Ferrochelatase - Yersinia enterocolitica Length = 322 Score = 85.0 bits (201), Expect = 1e-15 Identities = 55/180 (30%), Positives = 89/180 (49%), Gaps = 2/180 (1%) Frame = +1 Query: 4 RVVIFSQYPQYSCATTGSSLNAVADYYKN-KQIPRDIRFSLIERWGSHPLLARVFAERIK 180 ++V+ YPQYSC+T+ + +AVA K +++P S I + HP + ++ Sbjct: 121 KLVVLPLYPQYSCSTSAAVWDAVARILKGYRRLPS---ISFIRDYAEHPAYISALKQSVE 177 Query: 181 EKLTLFPAGVRDQVLILFTAHSLPLKAVSRGDTYPHEVAASVSATVSELGA-VNPHRLVW 357 G D++++ F H +P + GD YP + A +E+ + + Sbjct: 178 NSFVQH--GKPDRLVLSF--HGIPKRYAQLGDDYPQRCEDTSRALRAEIALPAEQIMMTY 233 Query: 358 QSKVGPLPWLQPYTDDAIKSYAKQGVKYMILVPIAFVNEHIETLHELDIEYCDEVAKEAG 537 QS+ G PWL PYTD+ +KS QGVK++ L+ F + +ETL E+ E EV AG Sbjct: 234 QSRFGREPWLTPYTDETLKSLPSQGVKHIQLICPGFSADCLETLEEIK-EQNREVFIHAG 292 >UniRef50_Q72L32 Cluster: Ferrochelatase; n=2; Thermus thermophilus|Rep: Ferrochelatase - Thermus thermophilus (strain HB27 / ATCC BAA-163 / DSM 7039) Length = 317 Score = 84.2 bits (199), Expect = 2e-15 Identities = 47/166 (28%), Positives = 85/166 (51%), Gaps = 5/166 (3%) Frame = +1 Query: 58 SLNAVADYYKN-----KQIPRDIRFSLIERWGSHPLLARVFAERIKEKLTLFPAGVRDQV 222 SL +VA+Y + K +P I F +E + +HP L +A R++E ++ + Sbjct: 127 SLRSVAEYREKVDSALKTLPEPIDFVWVESYEAHPGLIAAYARRLEE--VIWRLKNPGKA 184 Query: 223 LILFTAHSLPLKAVSRGDTYPHEVAASVSATVSELGAVNPHRLVWQSKVGPLPWLQPYTD 402 +FTAHS+PL AV +GD YP +V + +L H + P PWL P + Sbjct: 185 AYVFTAHSIPLSAVEKGDPYPRQVEKTAELIAKKLALPRFHVAYQSAGRTPEPWLGPDIN 244 Query: 403 DAIKSYAKQGVKYMILVPIAFVNEHIETLHELDIEYCDEVAKEAGI 540 + +++ ++G + + + + F +H+E ++LD+E A+E G+ Sbjct: 245 ELLRTLKEEGYEEVAVQAVGFPADHLEVFYDLDLE-AQATARELGL 289 >UniRef50_Q5FSJ9 Cluster: Ferrochelatase; n=1; Gluconobacter oxydans|Rep: Ferrochelatase - Gluconobacter oxydans (Gluconobacter suboxydans) Length = 343 Score = 82.2 bits (194), Expect = 9e-15 Identities = 49/180 (27%), Positives = 88/180 (48%), Gaps = 1/180 (0%) Frame = +1 Query: 1 ERVVIFSQYPQYSCATTGSSLNAVADYYKNKQIPRDIRFSLIERWGSHPLLARVFAERIK 180 +R++ + YPQYS TT ++ + + + ++ R + + HP R ++ Sbjct: 136 DRIISIALYPQYSATTTATANDQL--FRALMRLRRQPAVLTVPSFPDHPAFIRALETSVQ 193 Query: 181 EKLTLFPAGVRDQVLILFTAHSLPLKAVSRGDTYPHEVAASVSATVSELGAVNPHR-LVW 357 + TL + Q ++ + H LP + +GDTY E ++SA LG L + Sbjct: 194 D--TLAGLSFKPQQIVA-SFHGLPKTCIEKGDTYRDECERTISALRQALGLSEEQMPLTF 250 Query: 358 QSKVGPLPWLQPYTDDAIKSYAKQGVKYMILVPIAFVNEHIETLHELDIEYCDEVAKEAG 537 QS+ GPL W+QPYT +K+ QG+ + ++ F+ + +ETL E+ E +E + G Sbjct: 251 QSRFGPLEWVQPYTAPFVKALPAQGITKIAVIMPGFMVDCLETLDEIGNELREEFMEAGG 310 >UniRef50_A6DEA9 Cluster: Ferrochelatase; n=1; Caminibacter mediatlanticus TB-2|Rep: Ferrochelatase - Caminibacter mediatlanticus TB-2 Length = 298 Score = 81.8 bits (193), Expect = 1e-14 Identities = 58/195 (29%), Positives = 94/195 (48%) Frame = +1 Query: 1 ERVVIFSQYPQYSCATTGSSLNAVADYYKNKQIPRDIRFSLIERWGSHPLLARVFAERIK 180 E ++ YP YS T S L D KN ++ +I + + F E IK Sbjct: 103 EEIIFLPLYPHYSFTTFESCL----DDLKNTNFKGKVK--IINPFFEN----EKFNEIIK 152 Query: 181 EKLTLFPAGVRDQVLILFTAHSLPLKAVSRGDTYPHEVAASVSATVSELGAVNPHRLVWQ 360 E + ++ LI F+AH +P K +++GD Y + + V +L L +Q Sbjct: 153 ENILKEVDNPKEWNLI-FSAHGIPKKLINKGDKYYSHILSHVEILKKKLSEFKSINLAFQ 211 Query: 361 SKVGPLPWLQPYTDDAIKSYAKQGVKYMILVPIAFVNEHIETLHELDIEYCDEVAKEAGI 540 S+ GPL WL+PY ++ +K Y + V ++ P++F+ ++ ET EL IEY E+AKE GI Sbjct: 212 SRFGPLEWLKPYLNEELKKYKNENV---LVYPLSFMIDNSETDLELSIEY-KELAKEYGI 267 Query: 541 VQIERAETPEHSSHI 585 + + P + Sbjct: 268 KNYKVVKCPNDDEKV 282 >UniRef50_Q8DFM2 Cluster: Ferrochelatase; n=16; Gammaproteobacteria|Rep: Ferrochelatase - Vibrio vulnificus Length = 319 Score = 81.8 bits (193), Expect = 1e-14 Identities = 49/167 (29%), Positives = 82/167 (49%), Gaps = 1/167 (0%) Frame = +1 Query: 1 ERVVIFSQYPQYSCATTGSSLNAVADYYKNKQIPRDIRFSLIERWGSHPLLARVFAERIK 180 + + + YPQYS TTG++ +A+A + + I+F I + HPL + AE ++ Sbjct: 120 DEICVLPLYPQYSGTTTGAAYDALAHALRKVAVVPSIQF--IRDYHDHPLYIKALAESVR 177 Query: 181 EKLTLFPAGVRDQVLILFTAHSLPLKAVSRGDTYPHEVAASVSATVSELGAVNPH-RLVW 357 + + G D +L + H +P + GD YP + ELG + Sbjct: 178 QSWQV--QGKGDYLLCSY--HGIPQRYADNGDVYPLHCEMTTELLRLELGLDKSQIGTTY 233 Query: 358 QSKVGPLPWLQPYTDDAIKSYAKQGVKYMILVPIAFVNEHIETLHEL 498 QS+ G WLQPYTD ++S +G+K + ++ AF + +ETL E+ Sbjct: 234 QSRFGREEWLQPYTDKTLESLPAKGIKSLDVITPAFSVDCLETLEEI 280 >UniRef50_Q2GCY1 Cluster: Ferrochelatase; n=1; Neorickettsia sennetsu str. Miyayama|Rep: Ferrochelatase - Neorickettsia sennetsu (strain Miyayama) Length = 325 Score = 81.0 bits (191), Expect = 2e-14 Identities = 58/171 (33%), Positives = 89/171 (52%), Gaps = 2/171 (1%) Frame = +1 Query: 4 RVVIFSQYPQYSCATTGSSLNAVADYYKNKQIPRDIRFSLIERWGSHPLLARVFAERIKE 183 + ++ YPQ+S T SL+++ K +IP + + + + L E I Sbjct: 115 KAILLPLYPQFSTTT---SLSSIEQCLKVLRIPTQV----VCCYYDNQLFIEAHVETI-- 165 Query: 184 KLTLFP-AGVRDQVLILFTAHSLPLKAVSRGDTYPHEVAASVSATVSELGAVN-PHRLVW 357 L ++ A + +ILF+AH LPL + GD Y +V V V+ L N L + Sbjct: 166 -LPIYAEACAFGKPIILFSAHGLPLSVIKAGDPYKFQVEEFVRRVVAALKIENLDWELCY 224 Query: 358 QSKVGPLPWLQPYTDDAIKSYAKQGVKYMILVPIAFVNEHIETLHELDIEY 510 QS+VG WL P T I+S++++ + ++VPIAFV+EH ET ELDIEY Sbjct: 225 QSRVGKAKWLCPDTASTIQSHSERPI---VVVPIAFVSEHSETRVELDIEY 272 >UniRef50_Q8GCV0 Cluster: Ferrochelatase; n=1; Leptospira biflexa|Rep: Ferrochelatase - Leptospira biflexa Length = 362 Score = 81.0 bits (191), Expect = 2e-14 Identities = 41/100 (41%), Positives = 61/100 (61%), Gaps = 3/100 (3%) Frame = +1 Query: 226 ILFTAHSLPLKAVSRGDTYPHEVAASVSATVSEL---GAVNPHRLVWQSKVGPLPWLQPY 396 ++F+AH +P++ + +GD Y EV SV EL G + +QSKVGP W +P Sbjct: 207 LVFSAHGVPMRLIHKGDRYMEEVELSVKGIADELSKFGFNGGVHISYQSKVGPAKWTEPS 266 Query: 397 TDDAIKSYAKQGVKYMILVPIAFVNEHIETLHELDIEYCD 516 T I S AKQG K++ + PI+FV++HIETL E+ ++ D Sbjct: 267 TIQMISSLAKQG-KHIAVYPISFVSDHIETLEEIGEQFKD 305 >UniRef50_Q7VHH1 Cluster: Ferrochelatase; n=1; Helicobacter hepaticus|Rep: Ferrochelatase - Helicobacter hepaticus Length = 311 Score = 81.0 bits (191), Expect = 2e-14 Identities = 63/187 (33%), Positives = 92/187 (49%), Gaps = 5/187 (2%) Frame = +1 Query: 1 ERVVIFSQYPQYSCATTGSSL-NAVADYYKNKQIPRDIRFSLIERWGSHPLLARVFAERI 177 + VV+FS YPQ+S +T SSL +A A K P S + +HP ERI Sbjct: 104 QSVVLFSLYPQFSYSTIASSLIDAKAALQKLAFTPTLYEIS---SYHTHPDYISCIIERI 160 Query: 178 KEKLTLFPAGVRDQVLILFTAHSLPLKAVSRGDTYPHEVAAS---VSATVSELGAV-NPH 345 KE L A ++ ++L +AHSLP + GD Y + + + + G V Sbjct: 161 KESLG---ADNPNEFVLLLSAHSLPQSRIDEGDPYQKQCEENKEVIQKALESEGIVFKKI 217 Query: 346 RLVWQSKVGPLPWLQPYTDDAIKSYAKQGVKYMILVPIAFVNEHIETLHELDIEYCDEVA 525 L +QSKVG + W+ P T + I Y K MI+ P++F ++ ET +EL I Y +A Sbjct: 218 ALAYQSKVGRMKWIGPSTKETITKYKKH---KMIIFPLSFTLDNSETEYELKILYA-SLA 273 Query: 526 KEAGIVQ 546 KE + Q Sbjct: 274 KELNVPQ 280 >UniRef50_UPI0000E4A92D Cluster: PREDICTED: similar to ferrochelatase; n=1; Strongylocentrotus purpuratus|Rep: PREDICTED: similar to ferrochelatase - Strongylocentrotus purpuratus Length = 261 Score = 55.6 bits (128), Expect(2) = 3e-14 Identities = 25/48 (52%), Positives = 38/48 (79%), Gaps = 3/48 (6%) Frame = +1 Query: 1 ERVVIFSQYPQYSCATTGSSLNAVADYY-KNKQIPRD--IRFSLIERW 135 ER + F+QYPQYSC+TTGSSLNA+ +Y KN ++ + +++S+I+RW Sbjct: 152 ERAIAFTQYPQYSCSTTGSSLNAIYRHYAKNPEMVANSTMKWSVIDRW 199 Score = 45.2 bits (102), Expect(2) = 3e-14 Identities = 19/39 (48%), Positives = 27/39 (69%) Frame = +1 Query: 253 LKAVSRGDTYPHEVAASVSATVSELGAVNPHRLVWQSKV 369 ++ V+RGD YP EV A+V + L +P+RLVWQSK+ Sbjct: 206 VEVVNRGDPYPAEVGATVQRVMERLNFSHPYRLVWQSKM 244 >UniRef50_Q3AEU4 Cluster: Ferrochelatase; n=1; Carboxydothermus hydrogenoformans Z-2901|Rep: Ferrochelatase - Carboxydothermus hydrogenoformans (strain Z-2901 / DSM 6008) Length = 292 Score = 79.4 bits (187), Expect = 6e-14 Identities = 44/95 (46%), Positives = 58/95 (61%), Gaps = 1/95 (1%) Frame = +1 Query: 226 ILFTAHSLPLKAVSRGDTYPHEVAASVSATVSELGAVNPHRLVWQSK-VGPLPWLQPYTD 402 I+FTAH+LP KA+ +GD Y E +V A P R +QSK WL+P D Sbjct: 165 IIFTAHNLPKKAIEQGDPYFAEFLKTVEAIARTFPF--PWRYAFQSKGKSGEEWLKPEVD 222 Query: 403 DAIKSYAKQGVKYMILVPIAFVNEHIETLHELDIE 507 D I S+ QGV+ +I+ PI FV +HIETL++LDIE Sbjct: 223 DVIISWQNQGVENIIINPIGFVADHIETLYDLDIE 257 >UniRef50_Q62HD1 Cluster: Ferrochelatase; n=82; cellular organisms|Rep: Ferrochelatase - Burkholderia mallei (Pseudomonas mallei) Length = 367 Score = 79.4 bits (187), Expect = 6e-14 Identities = 50/182 (27%), Positives = 84/182 (46%), Gaps = 3/182 (1%) Frame = +1 Query: 1 ERVVIFSQYPQYSCATTGSSLNAVADYYKNKQIPRDIRFSLIERWGSHPLLARVFAERIK 180 ERV++ YPQYS +TT ++ +A + ++R + + HP AE+++ Sbjct: 147 ERVLLLPMYPQYSSSTTATAFDAAFAALGRMRNQPEVR--TVRHYADHPAYIHALAEQVR 204 Query: 181 EKLTLF--PAGVRDQVLILFTAHSLPLKAVSRGDTYPHEVAASVSATVSELGAVNPH-RL 351 + PA L+L + H +P + + GD Y + + + +S LG R+ Sbjct: 205 QYWAAHGRPAFDAGDKLVL-SFHGVPKRTLDLGDPYHDQCQQTAALLMSALGLTTFECRV 263 Query: 352 VWQSKVGPLPWLQPYTDDAIKSYAKQGVKYMILVPIAFVNEHIETLHELDIEYCDEVAKE 531 +QS+ G WLQPYT +K GV+ + F + +ET+ E+ IE DE Sbjct: 264 TFQSRFGKAEWLQPYTAPTLKELGAAGVRRADVFCPGFTADCLETIEEIGIEVRDEFVHG 323 Query: 532 AG 537 G Sbjct: 324 GG 325 >UniRef50_A6VXF8 Cluster: Ferrochelatase; n=1; Marinomonas sp. MWYL1|Rep: Ferrochelatase - Marinomonas sp. MWYL1 Length = 330 Score = 78.6 bits (185), Expect = 1e-13 Identities = 48/182 (26%), Positives = 87/182 (47%), Gaps = 2/182 (1%) Frame = +1 Query: 1 ERVVIFSQYPQYSCATTGSSLNAVADYYKNKQIPRDIRFSLIERWGSHPLLARVFAERIK 180 + +++ YPQ+S TT ++ + + KN P L+ + HP+ + + ++ Sbjct: 126 KNIIVIPMYPQFSATTTAAAYDRLMKSLKN--CPHWPSLQLLHDYADHPMYIKALSNSVR 183 Query: 181 EKLTLFPAGVRDQVLILFTAHSLPLKAVSRGDTYPHEVAASVSATVSELGAVNPHRL--V 354 + G R +++ + H +P + V+ GD Y + S V+E + H V Sbjct: 184 AQWD--KQGERRHLVLSY--HGIPKRYVTNGDPYARR-CETTSRLVAEELELGDHEWTHV 238 Query: 355 WQSKVGPLPWLQPYTDDAIKSYAKQGVKYMILVPIAFVNEHIETLHELDIEYCDEVAKEA 534 +QS+ G WL+PY D +K+ GVK + ++ AF + IETL E+ +E DE Sbjct: 239 YQSRFGREEWLKPYADATLKALPSMGVKKINIISPAFSIDCIETLEEVTLELGDEFKNNG 298 Query: 535 GI 540 G+ Sbjct: 299 GL 300 >UniRef50_Q9PI08 Cluster: Ferrochelatase; n=16; Campylobacter|Rep: Ferrochelatase - Campylobacter jejuni Length = 303 Score = 78.6 bits (185), Expect = 1e-13 Identities = 49/171 (28%), Positives = 85/171 (49%), Gaps = 1/171 (0%) Frame = +1 Query: 1 ERVVIFSQYPQYSCATTGSSLNAVADYYKNKQIPRDIRFSLIERWGSHPLLARVFAERIK 180 + +++F YP +SC T SSL + + ++I ++ I+ + + L + I Sbjct: 112 DEIILFPLYPHHSCTTVTSSLEVLQNEISKQKIQAKVK--TIDIFYKNELYNEMIVSHIL 169 Query: 181 EKLTLFPAGVRDQVLILFTAHSLPLKAVSRGDTYPHEVAASVSATVSEL-GAVNPHRLVW 357 K + F D +++F+AHSLP + +GD Y V V +L + L + Sbjct: 170 AKKSKF-----DAKILIFSAHSLPQSIIDKGDLYEKHVNDHVEILKEKLKDHFDEFILAY 224 Query: 358 QSKVGPLPWLQPYTDDAIKSYAKQGVKYMILVPIAFVNEHIETLHELDIEY 510 QSK+GP+ WL+P T D + + + + Y PI+F + ET+ EL +EY Sbjct: 225 QSKLGPVKWLEPNTSDVLANLNDKALIY----PISFCIDCSETIFELGMEY 271 >UniRef50_Q1ITV1 Cluster: Ferrochelatase; n=2; Acidobacteria|Rep: Ferrochelatase - Acidobacteria bacterium (strain Ellin345) Length = 303 Score = 78.2 bits (184), Expect = 1e-13 Identities = 54/185 (29%), Positives = 92/185 (49%), Gaps = 5/185 (2%) Frame = +1 Query: 40 CATTGSSLNAVADYYK---NKQIPRDIRFSLIERWGSHPLLARVFAERIKEKLTLFPAGV 210 C +S +V Y K K P + F +E W HPLL + FAE + A Sbjct: 102 CLAPQNSRTSVGLYRKALMEKNPPFTVDF--VESWHDHPLLIQAFAENHRAGYEKARAEA 159 Query: 211 RDQVLILFTAHSLPLKAVSRGDTYPHEVAASVSATVSELGAVNP-HRLVWQSK-VGPLPW 384 + +FTAHS+P + ++ GD Y + + + LG + R +QS+ + W Sbjct: 160 SHDLPRIFTAHSVPERTITEGDPYEAQTRETAALVAKGLGLKDAVWRFAFQSQGMSGGTW 219 Query: 385 LQPYTDDAIKSYAKQGVKYMILVPIAFVNEHIETLHELDIEYCDEVAKEAGIVQIERAET 564 P + ++ AK+G + + PI FV +H+E L+++DI + D A++ G ++I RAE+ Sbjct: 220 RGPTVESTLEGLAKEGHRGVFFQPIGFVCDHVEVLYDIDIGFRD-FAEKLG-MKIWRAES 277 Query: 565 PEHSS 579 +S+ Sbjct: 278 LNNSA 282 >UniRef50_Q67T48 Cluster: Ferrochelatase; n=1; Symbiobacterium thermophilum|Rep: Ferrochelatase - Symbiobacterium thermophilum Length = 320 Score = 77.4 bits (182), Expect = 3e-13 Identities = 49/179 (27%), Positives = 86/179 (48%), Gaps = 1/179 (0%) Frame = +1 Query: 4 RVVIFSQYPQYSCATTGSSLNAVADYYKN-KQIPRDIRFSLIERWGSHPLLARVFAERIK 180 R+++ +PQYS TT + + V + +P I I + +HP ERI Sbjct: 121 RLLVLPLFPQYSSTTTAAVWSKVQKALDGWRDLPEQI---FIRDFPTHPKYLAFLTERIS 177 Query: 181 EKLTLFPAGVRDQVLILFTAHSLPLKAVSRGDTYPHEVAASVSATVSELGAVNPHRLVWQ 360 + G D +++ + HS+P + GD Y + ++ A + + +Q Sbjct: 178 GYIA--EKGRPDALVLSY--HSIPQAYTASGDDYAAQCESTTDAVRDRFPDLKIV-MGYQ 232 Query: 361 SKVGPLPWLQPYTDDAIKSYAKQGVKYMILVPIAFVNEHIETLHELDIEYCDEVAKEAG 537 SK G PWL+P TD+ ++ + G +++ ++ F + IETLHEL++EY +E K G Sbjct: 233 SKFGNDPWLEPATDEVLRELVRTGHRHVAVMAPGFAADCIETLHELEVEYAEEFVKAGG 291 >UniRef50_Q03Z41 Cluster: Ferrochelatase; n=1; Leuconostoc mesenteroides subsp. mesenteroides ATCC 8293|Rep: Ferrochelatase - Leuconostoc mesenteroides subsp. mesenteroides (strain ATCC 8293 /NCDO 523) Length = 315 Score = 77.0 bits (181), Expect = 3e-13 Identities = 49/179 (27%), Positives = 90/179 (50%), Gaps = 2/179 (1%) Frame = +1 Query: 7 VVIFSQYPQYSCATTGSSLNAVADYYKNKQIPRDIRFSLIERWGSHPLLARVFAERIKEK 186 +V+ +PQYS +T S ++ V KN ++++ + + + A I+E Sbjct: 120 IVVLPLFPQYSVTSTQSVIDQVRKADKN--------INIVKSFYNDEAYLDLLARDIREA 171 Query: 187 LTLFPAGVRDQVLILFTAHSLPLKAVSRGDTYPHEVAASVSATVSELGAVNPHRL--VWQ 360 + D+++I + H +P V RGD Y A+ + +G + P V+Q Sbjct: 172 ---WAKNDYDRLIISY--HGVPESYVRRGDPYVDHCTATTQGVLERVGPLTPDNTHQVFQ 226 Query: 361 SKVGPLPWLQPYTDDAIKSYAKQGVKYMILVPIAFVNEHIETLHELDIEYCDEVAKEAG 537 S+ GP W++PY D ++S QG+K +++ AFV + +ET+ E+ +E D + K+AG Sbjct: 227 SRFGPTEWVKPYLSDTLRSLPSQGIKRVLVATPAFVADCLETIEEIHVENHD-IFKQAG 284 >UniRef50_P57874 Cluster: Ferrochelatase; n=1; Pasteurella multocida|Rep: Ferrochelatase - Pasteurella multocida Length = 326 Score = 76.6 bits (180), Expect = 4e-13 Identities = 49/181 (27%), Positives = 84/181 (46%), Gaps = 1/181 (0%) Frame = +1 Query: 1 ERVVIFSQYPQYSCATTGSSLNAVADYYKNKQIPRDIRFSLIERWGSHPLLARVFAERIK 180 + +++F YPQYS +TTG+ +A A K ++ + F I + ++ I+ Sbjct: 124 DNLIVFPLYPQYSSSTTGAVFDAFAQVLKTQR--GVLPFDFIHSYHTNEDYIAALVTTIQ 181 Query: 181 EKLTLFPAGVRDQVLILFTAHSLPLKAVSRGDTYPHEVAASVSATVSELGAV-NPHRLVW 357 E + +LF+ H +P++ + GD Y +V A + LG N L + Sbjct: 182 EHF-------QPDEFLLFSFHGIPVRYENMGDYYREHCKQTVLAVIDRLGLTENQWGLSF 234 Query: 358 QSKVGPLPWLQPYTDDAIKSYAKQGVKYMILVPIAFVNEHIETLHELDIEYCDEVAKEAG 537 QS+ G WLQPYTD + Q ++ M ++ F + +ETL E++ E + G Sbjct: 235 QSRFGKEEWLQPYTDQFLAQAPSQNIQKMAVICPGFAADCLETLEEIEEENKEIFLANGG 294 Query: 538 I 540 I Sbjct: 295 I 295 >UniRef50_A5EXB1 Cluster: Ferrochelatase; n=1; Dichelobacter nodosus VCS1703A|Rep: Ferrochelatase - Dichelobacter nodosus (strain VCS1703A) Length = 345 Score = 75.8 bits (178), Expect = 8e-13 Identities = 51/195 (26%), Positives = 87/195 (44%), Gaps = 1/195 (0%) Frame = +1 Query: 4 RVVIFSQYPQYSCATTGSSLNAVADYYKNKQIPRDIRFSLIERWGSHPLLARVFAERIKE 183 ++++ YPQY+ ATT S +AVA + + +IRF + W H A + Sbjct: 131 QLLVIPMYPQYAEATTASVFDAVAAALEKTRALPEIRF--VHHWHDHKNYLDALAAAFQH 188 Query: 184 KLTLFPAGVRDQVLILFTAHSLPLKAVSRGDTYPHEVAASVSATVSELGAVNPH-RLVWQ 360 L+ A L+L + H +P ++ GD Y + + H ++++Q Sbjct: 189 YLSKNGA----PQLLLLSFHGVPKSVITEGDPYYDFCLETADLFAKRVHFPKEHIKVIFQ 244 Query: 361 SKVGPLPWLQPYTDDAIKSYAKQGVKYMILVPIAFVNEHIETLHELDIEYCDEVAKEAGI 540 S+ G PWL+PY D+ I K+G+ + ++ F + +ETL E+ + Y + G Sbjct: 245 SRFGRKPWLEPYADEIIADLPKRGITKIAVMCPGFSADCLETLDEIALRYRALFLQSGGK 304 Query: 541 VQIERAETPEHSSHI 585 HSSHI Sbjct: 305 QYDYIPALNTHSSHI 319 >UniRef50_A6QAW0 Cluster: Ferrochelatase; n=1; Sulfurovum sp. NBC37-1|Rep: Ferrochelatase - Sulfurovum sp. (strain NBC37-1) Length = 316 Score = 75.4 bits (177), Expect = 1e-12 Identities = 53/181 (29%), Positives = 96/181 (53%), Gaps = 4/181 (2%) Frame = +1 Query: 1 ERVVIFSQYPQYSCATTGSSLNAVADYYKNKQIPRDIRFSLIERWGSHPLLARVFAERIK 180 E +++F YPQYS TT SS+ + + + + + + ++I+ + E+I Sbjct: 114 EELILFPMYPQYSTTTTLSSIEDIEE--RCEAMGYAPKITVIDPYYDDYTYIEACCEKIL 171 Query: 181 EKLTLFPAGVRDQVLILFTAHSLPLKAVSRGDTYPHEVAASVSATVSELG--AVNPH--R 348 E + + +L +AH LP+ + GD Y ++V + SA + L V+ H + Sbjct: 172 E---VAEGKETKEYDLLLSAHGLPMSIIKAGDPYQNQVEGNASAIKTYLACKGVDFHDIK 228 Query: 349 LVWQSKVGPLPWLQPYTDDAIKSYAKQGVKYMILVPIAFVNEHIETLHELDIEYCDEVAK 528 LV+QSKVG WL+P D +++ + V ++ P+AF ++ ET+ ELDIE+ E+A+ Sbjct: 229 LVYQSKVGSSAWLEPNLVDVLRNPTHRKV---LIYPLAFTLDNSETVFELDIEH-REIAE 284 Query: 529 E 531 + Sbjct: 285 K 285 >UniRef50_UPI0000DAE46A Cluster: hypothetical protein Rgryl_01000362; n=1; Rickettsiella grylli|Rep: hypothetical protein Rgryl_01000362 - Rickettsiella grylli Length = 318 Score = 74.9 bits (176), Expect = 1e-12 Identities = 41/169 (24%), Positives = 81/169 (47%), Gaps = 1/169 (0%) Frame = +1 Query: 7 VVIFSQYPQYSCATTGSSLNAVADYYKNKQIPRDIRFSLIERWGSHPLLARVFAERIKEK 186 + I YPQYS TT S + ++ +++ ++ I+ W + R + + I + Sbjct: 120 ITILPLYPQYSATTTASCFDQISQFFQTSRVIPHIK------WITSYFDQRWYIKAIVSQ 173 Query: 187 LTLFPAGVRDQVLILFTAHSLPLKAVSRGDTYPHEVAASVSATVSELGAV-NPHRLVWQS 363 + A +LF+ H LP + + GD Y ++V +L + +++V+QS Sbjct: 174 IKKMRAKQSQPSYLLFSFHGLPQRYIENGDPYQQHCFSTVRLIAEQLQLTKDTYQVVFQS 233 Query: 364 KVGPLPWLQPYTDDAIKSYAKQGVKYMILVPIAFVNEHIETLHELDIEY 510 + G WL+PY D +++ +G+K + ++ F + +ETL E+ Y Sbjct: 234 RFGKTAWLKPYCDRVLQTLPARGIKNVTIICPGFAVDCLETLEEISKRY 282 >UniRef50_A1K8P4 Cluster: Ferrochelatase; n=3; Betaproteobacteria|Rep: Ferrochelatase - Azoarcus sp. (strain BH72) Length = 363 Score = 74.9 bits (176), Expect = 1e-12 Identities = 50/170 (29%), Positives = 87/170 (51%), Gaps = 2/170 (1%) Frame = +1 Query: 4 RVVIFSQYPQYSCATTGSSLNAVADYYKNKQIPRDIRFSLIERWGSHPLLARVFAERIKE 183 R+++ YPQY+ +TT S ++ VA ++ + ++RF + + P A ++E Sbjct: 136 RILVVPMYPQYAASTTASVMDEVARCLQHWRNLPELRF--VRSFHDDPGYIGALAASVRE 193 Query: 184 KLTLFPAGVRDQVLILFTAHSLPLKAVSRGDTYPHEVAASVSATVSELGAVNPHRLV--W 357 T G D++L+ F H LP + RGD Y E + LG P R++ + Sbjct: 194 HWTRH--GQPDRLLMSF--HGLPRYTLERGDPYHCECHRTARLLAESLGLA-PERVIVSF 248 Query: 358 QSKVGPLPWLQPYTDDAIKSYAKQGVKYMILVPIAFVNEHIETLHELDIE 507 QS+ G WL+PYT +++ A+ GV + ++ FV + +ETL E+ +E Sbjct: 249 QSRFGRTRWLEPYTQPTLEALARDGVGRVDVMCPGFVADCLETLEEIAME 298 >UniRef50_Q5QVZ8 Cluster: Ferrochelatase; n=17; Gammaproteobacteria|Rep: Ferrochelatase - Idiomarina loihiensis Length = 364 Score = 74.9 bits (176), Expect = 1e-12 Identities = 52/170 (30%), Positives = 88/170 (51%), Gaps = 2/170 (1%) Frame = +1 Query: 4 RVVIFSQYPQYSCATTGSSLNAVA-DYYKNKQIPRDIRFSLIERWGSHPLLARVFAERIK 180 ++++ YPQYS +TT S+ +A+A D+ K + +P ++RF I + A+RI+ Sbjct: 137 KLLVLPLYPQYSASTTASTFDALAKDFTKRRWLP-ELRF--ITHYHDFSPFIEAAAQRIE 193 Query: 181 EKLTLFPAGVRDQVLILFTAHSLPLKAVSRGDTYPHEVAASVSATVSELGAVNPHRLV-W 357 + G D+ +LF+ H +PL+ + GD Y E + LG L + Sbjct: 194 KHWDAH--GRADK--LLFSYHGIPLRYLKNGDPYHCECYKTSRLLAERLGLGKDEYLTTF 249 Query: 358 QSKVGPLPWLQPYTDDAIKSYAKQGVKYMILVPIAFVNEHIETLHELDIE 507 QS+ G WLQPYTD +K+ +GVK + + F ++ +ET+ E+ E Sbjct: 250 QSRFGREEWLQPYTDMTMKALPGKGVKSVQVFCPGFSSDCLETVEEIGEE 299 >UniRef50_Q6F7N0 Cluster: Ferrochelatase; n=5; Moraxellaceae|Rep: Ferrochelatase - Acinetobacter sp. (strain ADP1) Length = 340 Score = 74.9 bits (176), Expect = 1e-12 Identities = 48/181 (26%), Positives = 89/181 (49%), Gaps = 2/181 (1%) Frame = +1 Query: 1 ERVVIFSQYPQYSCATTGSSLNAVADYY-KNKQIPRDIRFSLIERWGSHPLLARVFAERI 177 E V++ +PQYS +T +A A++ K + +P ++I+ + HP VF + + Sbjct: 128 EHVILLPLFPQYSATSTAPLYDAFANWIPKQRHLPG---LTIIKDYYRHP----VFIQAL 180 Query: 178 KEKLTLFPAGVRDQVLILFTAHSLPLKAVSRGDTYPHEVAASVSATVSELGAV-NPHRLV 354 + F +L + H +P +GD Y + +LG + + Sbjct: 181 VSSVQRFQQQHGKPQKLLMSFHGIPQPYADKGDPYADRCRETARLVAKQLGLTPDDWAIS 240 Query: 355 WQSKVGPLPWLQPYTDDAIKSYAKQGVKYMILVPIAFVNEHIETLHELDIEYCDEVAKEA 534 +QS+ G W++PYTD+ + ++A G+K + ++ AF + +ETL EL+I+ E+ EA Sbjct: 241 FQSRFGKQEWVKPYTDELLTTWAANGIKSVQILSPAFSADCLETLEELEIQNA-ELFLEA 299 Query: 535 G 537 G Sbjct: 300 G 300 >UniRef50_Q8D226 Cluster: Ferrochelatase; n=1; Wigglesworthia glossinidia endosymbiont of Glossina brevipalpis|Rep: Ferrochelatase - Wigglesworthia glossinidia brevipalpis Length = 321 Score = 74.5 bits (175), Expect = 2e-12 Identities = 47/170 (27%), Positives = 83/170 (48%), Gaps = 2/170 (1%) Frame = +1 Query: 4 RVVIFSQYPQYSCATTGSSLNAVADYYKN-KQIPRDIRFSLIERWGSHPLLARVFAERIK 180 +++I YPQYSC TT S L++V + K + IP I I + + IK Sbjct: 121 KLIILPMYPQYSCTTTASVLDSVCEVIKKYRNIPSII---FIRDYADNINYINAITNSIK 177 Query: 181 EKLTLFPAGVRDQVLILFTAHSLPLKAVSRGDTYPHEVAASVSATVSELGAVNPHRLV-W 357 + G+ + +++ F H +P K + GD Y + +S+L ++ + Sbjct: 178 KSFN--KNGIPEMLIMSF--HGIPKKYIKDGDDYLKRCNVTKKLVLSKLNFSRKKVIMSF 233 Query: 358 QSKVGPLPWLQPYTDDAIKSYAKQGVKYMILVPIAFVNEHIETLHELDIE 507 QSK G +PW+ P T + I K+G+K + ++ F ++ +ETL E+ I+ Sbjct: 234 QSKFGNIPWITPITSEVISFLPKKGIKNIQVICPGFSSDCLETLEEIKIQ 283 >UniRef50_O07401 Cluster: Ferrochelatase; n=1; Mycobacterium avium|Rep: Ferrochelatase - Mycobacterium avium Length = 335 Score = 74.5 bits (175), Expect = 2e-12 Identities = 48/127 (37%), Positives = 73/127 (57%), Gaps = 4/127 (3%) Frame = +1 Query: 199 PAGVRDQVLILFTAHSLPLKAVSR--GDTYPHEVAASVSATVSELGAVNPHRLVWQSKVG 372 PAG R ++FTAHS+P+ A R Y +VA + + G H LVWQS+ G Sbjct: 161 PAGAR----LVFTAHSVPVAADERLGPRLYSRQVAYAARLVAAAAGYAE-HDLVWQSRSG 215 Query: 373 P--LPWLQPYTDDAIKSYAKQGVKYMILVPIAFVNEHIETLHELDIEYCDEVAKEAGIVQ 546 P + WL+P D +++ A+ G + +I+ PI FV +HIE + +LD E + A+ AG++ Sbjct: 216 PPQVRWLEPDVADHLRALAESGTRAVIVCPIGFVADHIEVVWDLDEELRAQ-AESAGML- 273 Query: 547 IERAETP 567 + RA TP Sbjct: 274 MARASTP 280 >UniRef50_Q1ZEV1 Cluster: Ferrochelatase; n=1; Psychromonas sp. CNPT3|Rep: Ferrochelatase - Psychromonas sp. CNPT3 Length = 325 Score = 74.1 bits (174), Expect = 2e-12 Identities = 47/168 (27%), Positives = 80/168 (47%), Gaps = 1/168 (0%) Frame = +1 Query: 7 VVIFSQYPQYSCATTGSSLNAVADYYKNKQIPRDIRFSLIERWGSHPLLARVFAERIKEK 186 + I YPQYS +TT + V + K + I F + HPL + I+ Sbjct: 129 LTIIPLYPQYSVSTTAPVFDQVGRFIKGQINFPGITFK--NNYHDHPLYIDALCQSIQAH 186 Query: 187 LTLFPAGVRDQVLILFTAHSLPLKAVSRGDTYPHEVAASVSATVSELGAVNPHRLV-WQS 363 + ++F+ H +P + V +GD Y + SV+ V +LG + L+ +QS Sbjct: 187 WLNHGRAEK----LIFSFHGIPQRYVEKGDPYQWQCEQSVALVVKQLGLNSQDYLIAYQS 242 Query: 364 KVGPLPWLQPYTDDAIKSYAKQGVKYMILVPIAFVNEHIETLHELDIE 507 ++G WL PY D +KS A +G + ++ AF + +ETL E+ ++ Sbjct: 243 RMGREAWLMPYVDLELKSMANEGCSSVDIICPAFATDCLETLEEMAMQ 290 >UniRef50_Q8IFR0 Cluster: Ferrochelatase; n=10; Plasmodium|Rep: Ferrochelatase - Plasmodium falciparum Length = 350 Score = 74.1 bits (174), Expect = 2e-12 Identities = 49/170 (28%), Positives = 83/170 (48%), Gaps = 1/170 (0%) Frame = +1 Query: 4 RVVIFSQYPQYSCATTGSSLNAVADYYKNKQIPRDIRFSLIERWGSHPLLARVFAERIKE 183 ++++ YPQ + T S+L+ + KN ++RF S L +F +KE Sbjct: 147 KLLVLPLYPQSAECTVSSTLDCIGKNLKNWSNVPELRFI------SGYCLKDIFINTMKE 200 Query: 184 KLTLFPAGVRDQVLILFTAHSLPLKAVSRGDTYPHEVAASVSATVSELGA-VNPHRLVWQ 360 + + ++ + HSLP++ V +GD YP S V L + + LV+Q Sbjct: 201 NIENYWELYGKSKKLIISYHSLPIRNVIQGDLYPFFCIESTKKLVKSLNLNKDDYILVFQ 260 Query: 361 SKVGPLPWLQPYTDDAIKSYAKQGVKYMILVPIAFVNEHIETLHELDIEY 510 SK+ W++P +D I AKQG K + +V +F ++ +ETL E+ I Y Sbjct: 261 SKIKGQQWVKPCIEDTIIRLAKQGYKQIDIVSPSFSSDCLETLEEIKIHY 310 >UniRef50_P37408 Cluster: Ferrochelatase; n=5; Enterobacteriaceae|Rep: Ferrochelatase - Salmonella typhimurium Length = 320 Score = 74.1 bits (174), Expect = 2e-12 Identities = 51/181 (28%), Positives = 86/181 (47%), Gaps = 2/181 (1%) Frame = +1 Query: 1 ERVVIFSQYPQYSCATTGSSLNAVADYYKNKQIPRDIRFSLIERWGSHPLLARVFAERIK 180 + +V+ YPQYSC+T G+ + + K+ R S I + A+ + Sbjct: 120 DHIVVLPLYPQYSCSTVGAVWDELGRILARKR--RIPGISFIRDYADDGAYIDALAKSAR 177 Query: 181 EKLTLFPAGVRDQVLILFTAHSLPLKAVSRGDTYPHEVAASVSATVSELGAVNPHRLV-- 354 E G D +L+ + H +P + GD YP + VS LG + P +++ Sbjct: 178 ESFARH--GEPDVLLLSY--HGIPQRYADEGDDYPQRCRDTTRELVSALG-LPPEKVMMT 232 Query: 355 WQSKVGPLPWLQPYTDDAIKSYAKQGVKYMILVPIAFVNEHIETLHELDIEYCDEVAKEA 534 +QS+ G PWL PYTD+ +K ++G ++ ++ F + +ETL E+ E E+ EA Sbjct: 233 FQSRFGREPWLTPYTDETLKMLGEKGTGHIQVMCPGFAADCLETLEEI-AEQNREIFLEA 291 Query: 535 G 537 G Sbjct: 292 G 292 >UniRef50_Q97R30 Cluster: Ferrochelatase; n=18; Streptococcus|Rep: Ferrochelatase - Streptococcus pneumoniae Length = 364 Score = 72.1 bits (169), Expect = 9e-12 Identities = 47/164 (28%), Positives = 85/164 (51%), Gaps = 3/164 (1%) Frame = +1 Query: 103 RDIRFSLIERWGSHPLLARVFAERIKEKLTLFPAGVRDQVLILFTAHSLPLKAVSRGDTY 282 + I+F +I+ W L +A+ I + L +D ++F+AHS+P+ A+ GD Y Sbjct: 125 KQIQFLVIKDWYQEEALLNYWADEIAKILK--EEVKQDSFKVIFSAHSVPIFALDFGDPY 182 Query: 283 PHEVAASVSATVSELG-AVNPHRLVWQSK--VGPLPWLQPYTDDAIKSYAKQGVKYMILV 453 ++ + +LG + + WQS+ +G +PW++P + ++ + Y I V Sbjct: 183 IDQIFENSKLVAEKLGLSSEQYTNTWQSESDIG-IPWIKPDVLEYLREQTEHPDHY-IFV 240 Query: 454 PIAFVNEHIETLHELDIEYCDEVAKEAGIVQIERAETPEHSSHI 585 PI+F++EHIE L + D+E C ++ +E G V R P S + Sbjct: 241 PISFISEHIEVLFDNDVE-CYDLCQEFG-VNYHRPPMPNTDSRL 282 >UniRef50_Q9CFB4 Cluster: Ferrochelatase; n=3; Lactococcus lactis|Rep: Ferrochelatase - Lactococcus lactis subsp. lactis (Streptococcus lactis) Length = 314 Score = 70.9 bits (166), Expect = 2e-11 Identities = 52/181 (28%), Positives = 86/181 (47%), Gaps = 2/181 (1%) Frame = +1 Query: 1 ERVVIFSQYPQYSCATTGSSLNAVADYYKNKQIPRDIRFSLIERWGSHPLLARVFAERIK 180 E + + YPQYS T + V ++ RD F +E + + AE I+ Sbjct: 119 EEITVLPLYPQYSLTTVEPVIQQVKKIDDKIKVIRD--FHKVESYSD------LLAESIR 170 Query: 181 EKLTLFPAGVRDQVLILFTAHSLPLKAVSRG-DTYPHEVAASVSATVSELGA-VNPHRLV 354 EK + A D++++ + H +PL V++ D Y + + VS+LG + Sbjct: 171 EK---WQANDYDKLVLSY--HGIPLSYVTKKKDAYEEQCKETTRLVVSKLGLREEEYEHT 225 Query: 355 WQSKVGPLPWLQPYTDDAIKSYAKQGVKYMILVPIAFVNEHIETLHELDIEYCDEVAKEA 534 +QSK GP WL+P T D + K+ K +++ AFV + +ETL EL+IE + + Sbjct: 226 YQSKFGPEKWLEPATIDRVAELPKENAKKVLICSPAFVADCLETLFELEIENKEVFVENG 285 Query: 535 G 537 G Sbjct: 286 G 286 >UniRef50_A3QC13 Cluster: Ferrochelatase; n=5; Gammaproteobacteria|Rep: Ferrochelatase - Shewanella loihica (strain BAA-1088 / PV-4) Length = 355 Score = 70.5 bits (165), Expect = 3e-11 Identities = 48/180 (26%), Positives = 88/180 (48%), Gaps = 1/180 (0%) Frame = +1 Query: 1 ERVVIFSQYPQYSCATTGSSLNAVADYYKNKQIPRDIRFSLIERWGSHPLLARVFAERIK 180 +++++ YPQY+ TT S+ +A+ + + + F I + HP A+ I Sbjct: 155 DKLIVLPLYPQYAAPTTASAFDALTKELISWRYLPSLHF--INSYHDHPDYIAALADSIA 212 Query: 181 EKLTLFPAGVRDQVLILFTAHSLPLKAVSRGDTYPHEVAASVSATVSELGAVNPHRLV-W 357 + F + + L+L + H +P + ++ GD Y + V LG + + + Sbjct: 213 KD---FEQHGKPKKLVL-SYHGMPERNLNLGDPYYCLCQKTTRLVVERLGLTDDDYITTF 268 Query: 358 QSKVGPLPWLQPYTDDAIKSYAKQGVKYMILVPIAFVNEHIETLHELDIEYCDEVAKEAG 537 QS+ G WL PYTD ++++ AK+GV + +V AF + +ETL E++ E D + G Sbjct: 269 QSRFGKAKWLGPYTDASLEALAKEGVDDVAIVCPAFSADCLETLEEIEHENRDVFTQAGG 328 >UniRef50_Q9PFU1 Cluster: Ferrochelatase; n=13; Xanthomonadaceae|Rep: Ferrochelatase - Xylella fastidiosa Length = 320 Score = 70.5 bits (165), Expect = 3e-11 Identities = 52/176 (29%), Positives = 88/176 (50%), Gaps = 2/176 (1%) Frame = +1 Query: 4 RVVIFSQYPQYSCATTGSSLNAVADYYKNKQIPRDIRFSLIERWGSHPLLARVFAERIKE 183 R+VI YPQYS TT S + V + K + P+ ++ I+ + A I+ Sbjct: 122 RIVILPLYPQYSTTTTASVQDVVEAWCK--RTPQ-VQVECIQDYAEDSAWVAAVAASIRR 178 Query: 184 KLTLFPAGVRDQVLILFTAHSLPLKAVSRGDTYPH--EVAASVSATVSELGAVNPHRLVW 357 + A R + L +F+ H LP + + GD YP +V+AS+ A +L + L + Sbjct: 179 H---WQAHGRSEKL-MFSFHGLPQRVANNGDPYPQRCQVSASLIAAALDLNE-SEWVLGY 233 Query: 358 QSKVGPLPWLQPYTDDAIKSYAKQGVKYMILVPIAFVNEHIETLHELDIEYCDEVA 525 QS+ G WLQPY + + + A+ G++ LV F + +ETL E+ + + + +A Sbjct: 234 QSRFGAERWLQPYAEPTLWALAESGIRRFDLVCPGFSVDCLETLEEVALGFSETLA 289 >UniRef50_Q5P1H1 Cluster: Ferrochelatase; n=3; Betaproteobacteria|Rep: Ferrochelatase - Azoarcus sp. (strain EbN1) (Aromatoleum aromaticum (strain EbN1)) Length = 365 Score = 70.1 bits (164), Expect = 4e-11 Identities = 44/170 (25%), Positives = 86/170 (50%), Gaps = 2/170 (1%) Frame = +1 Query: 4 RVVIFSQYPQYSCATTGSSLNAVADYYKNKQIPRDIRFSLIERWGSHPLLARVFAERIKE 183 R+++ YPQY+ +TT S ++ VA + +IR+ + + HP A +++ Sbjct: 138 RILVVPLYPQYAASTTASVIDEVAGCLTRWRNLPEIRY--VRNFHDHPGYVGALARSVRD 195 Query: 184 KLTLFPAGVRDQVLILFTAHSLPLKAVSRGDTYPHEVAASVSATVSELGAVNPHR--LVW 357 G DQ+++ F H +P +++ GD Y E + ++L + P R L + Sbjct: 196 HWAKH--GEPDQLVMSF--HGIPKRSLDLGDPYHCECHVTARLLAAKLD-LPPERWQLTF 250 Query: 358 QSKVGPLPWLQPYTDDAIKSYAKQGVKYMILVPIAFVNEHIETLHELDIE 507 QS+ G WL+PYT +++ ++G + ++ F ++ +ETL E+ +E Sbjct: 251 QSRFGKAEWLKPYTQPTLEALGRKGTGRVDVICPGFASDCLETLEEIALE 300 >UniRef50_Q6MAW8 Cluster: Ferrochelatase; n=5; Bacteria|Rep: Ferrochelatase - Protochlamydia amoebophila (strain UWE25) Length = 347 Score = 70.1 bits (164), Expect = 4e-11 Identities = 58/195 (29%), Positives = 91/195 (46%), Gaps = 22/195 (11%) Frame = +1 Query: 1 ERVVIFSQYPQYSCATTGSSLNAVADYYKNKQIPRDIRFSLIERWGSHPLLARVFAERIK 180 + +VIF +PQY+ ATTGS V + + Q + F I + HP L F ER K Sbjct: 120 KEIVIFPLFPQYASATTGSVHQEVMKHLQQWQNIPTLTF--INSYPDHPGLVGAFCERAK 177 Query: 181 EKLTLFPAGVRDQVLILFTAHSLPLKAVSRGDT--------------------YPHEVAA 300 + + + D LF+ H LP + + +GD+ Y + Sbjct: 178 Q----YDLSIYDY--FLFSFHGLPERQIRKGDSTGKCLTENCCQVICSDNAFCYKAQCYR 231 Query: 301 SVSATVSELGA-VNPHRLVWQSKVGPLPWLQPYTDDAIKS-YAKQGVKYMILVPIAFVNE 474 + A S+L + + + +QS++G W+QPYT D +K AK K ++ P AFV + Sbjct: 232 TAKAIASKLRIKLEQYTVCFQSRLGKETWIQPYTSDLLKDCLAKNRKKILVFCP-AFVCD 290 Query: 475 HIETLHELDIEYCDE 519 +ET E+ IEY +E Sbjct: 291 CLETTCEVSIEYAEE 305 >UniRef50_Q8EBZ7 Cluster: Ferrochelatase 2; n=48; Proteobacteria|Rep: Ferrochelatase 2 - Shewanella oneidensis Length = 327 Score = 70.1 bits (164), Expect = 4e-11 Identities = 46/167 (27%), Positives = 81/167 (48%), Gaps = 1/167 (0%) Frame = +1 Query: 1 ERVVIFSQYPQYSCATTGSSLNAVADYYKNKQIPRDIRFSLIERWGSHPLLARVFAERIK 180 +++V+ YPQY+ TTGS+ +A+A + + F I + +P I+ Sbjct: 127 DKLVVLPLYPQYAAPTTGSAFDAIAKELSQWRYLPSLHF--INTYHDNPDFIAALVNSIR 184 Query: 181 EKLTLFPAGVRDQVLILFTAHSLPLKAVSRGDTYPHEVAASVSATVSELG-AVNPHRLVW 357 + F + Q L+L + H +P + + GD Y + +LG + + + + Sbjct: 185 DD---FDKHGKPQKLVL-SYHGMPERNLHLGDPYYCFCMKTTRLVAEQLGLSKDEFAITF 240 Query: 358 QSKVGPLPWLQPYTDDAIKSYAKQGVKYMILVPIAFVNEHIETLHEL 498 QS+ G WLQPYTD + + QGV+ + +V AF + +ETL E+ Sbjct: 241 QSRFGKAKWLQPYTDATMAALPSQGVRDVAIVCPAFSADCLETLEEI 287 >UniRef50_Q9Z7V1 Cluster: Ferrochelatase; n=12; Chlamydiaceae|Rep: Ferrochelatase - Chlamydia pneumoniae (Chlamydophila pneumoniae) Length = 327 Score = 69.3 bits (162), Expect = 7e-11 Identities = 45/162 (27%), Positives = 82/162 (50%) Frame = +1 Query: 25 YPQYSCATTGSSLNAVADYYKNKQIPRDIRFSLIERWGSHPLLARVFAERIKEKLTLFPA 204 +P ++ + TGS + + K +P +I S I ++GS + I++ L Sbjct: 122 FPHFTYSVTGSIVR-----FFMKHVP-EIPISWIPQFGSDSKFVSLITCHIRDFLQKLGI 175 Query: 205 GVRDQVLILFTAHSLPLKAVSRGDTYPHEVAASVSATVSELGAVNPHRLVWQSKVGPLPW 384 + + LF+ H LP++ +S+GD Y + S SA + + + L +QSK GP W Sbjct: 176 -LEKECCFLFSVHGLPVRYISQGDPYSKQCYESFSAITTNFKQ-SENFLCFQSKFGPGKW 233 Query: 385 LQPYTDDAIKSYAKQGVKYMILVPIAFVNEHIETLHELDIEY 510 L P T ++ +I+VP F+++H+ETL+E++ +Y Sbjct: 234 LSPSTAQLCQNIDTDKPN-VIVVPFGFISDHLETLYEIERDY 274 >UniRef50_Q81TU9 Cluster: Ferrochelatase 2; n=76; Bacillales|Rep: Ferrochelatase 2 - Bacillus anthracis Length = 319 Score = 68.9 bits (161), Expect = 9e-11 Identities = 39/138 (28%), Positives = 70/138 (50%), Gaps = 2/138 (1%) Frame = +1 Query: 124 IERWGSHPLLARVFAERIKEKLTLFPAGVRDQVLILFTAHSLPLKAVSRGDTYPHEVAAS 303 I++W P +A++IKE T +++ +++F+AHSLP K ++ GD Y ++ + Sbjct: 144 IDQWYDEPKFISYWADQIKETFTKIED--KEKAVVIFSAHSLPEKIIAAGDPYVEQLQHT 201 Query: 304 VSATVSELGAVNPHRLVWQSKVG-PLPWLQPYTDDAIKS-YAKQGVKYMILVPIAFVNEH 477 ++ + + + WQS P PW+ P D + + + + I P+ FV EH Sbjct: 202 AD-LIAAAANIQNYTIGWQSAGNTPDPWIGPDVQDLTRDLFEEYRYESFIYCPVGFVAEH 260 Query: 478 IETLHELDIEYCDEVAKE 531 +E L++ D E C V E Sbjct: 261 LEVLYDNDYE-CKVVTDE 277 >UniRef50_Q82KJ6 Cluster: Ferrochelatase; n=10; Actinobacteria (class)|Rep: Ferrochelatase - Streptomyces avermitilis Length = 375 Score = 68.5 bits (160), Expect = 1e-10 Identities = 50/166 (30%), Positives = 79/166 (47%), Gaps = 15/166 (9%) Frame = +1 Query: 112 RFSLIERWGSHPLLARVFAERIKEKLTLFPAGVRDQVLILFTAHSLPLKAV-SRGDTYPH 288 R + + +HP E + L P VR I FT HS+P A + G H Sbjct: 148 RVDKLRHYFNHPGFVEPMTEGVLRSLAELPEDVRPGAHIAFTTHSIPTAAADTSGPVEEH 207 Query: 289 -----------EVAASVSATV-SELGAVNPHRLVWQSKVGP--LPWLQPYTDDAIKSYAK 426 +VA ++ V E G +P +LV+QS+ G +PWL+P D ++ Sbjct: 208 GDGGAYVKQHLDVARLIADAVREETGIDHPWQLVYQSRSGAPHIPWLEPDICDHLQELHG 267 Query: 427 QGVKYMILVPIAFVNEHIETLHELDIEYCDEVAKEAGIVQIERAET 564 GV +++ PI FV++H+E L++LD E A+E G+ + R+ T Sbjct: 268 AGVPAVVMAPIGFVSDHMEVLYDLDTE-AKAKAEELGL-PVRRSAT 311 >UniRef50_Q5NFT3 Cluster: Ferrochelatase; n=11; Francisella tularensis|Rep: Ferrochelatase - Francisella tularensis subsp. tularensis Length = 333 Score = 68.1 bits (159), Expect = 2e-10 Identities = 51/180 (28%), Positives = 82/180 (45%), Gaps = 3/180 (1%) Frame = +1 Query: 7 VVIFSQYPQYSCATTGSSLNAVADYYKNKQIPRDIRFSLIERWGSHPLLARVFAERIKEK 186 ++IF YPQYS TT + + V Y ++ I + + + +++IKE Sbjct: 129 IIIFPLYPQYSATTTATVYDEV--YRVLSKLRWQPTIKGINPYYDNKFHIQTISQQIKEH 186 Query: 187 LTLFPAGVRDQVLILFTAHSLPLKAVSRGDTYPHEVAASVSATVSELGAVNPH---RLVW 357 L + D VL F+ H LP + +GD Y + EL P+ L + Sbjct: 187 LKKLDS-TPDTVL--FSFHGLPKEYFDKGDPYYCHCYKTYRLVKEELQNEYPNIDFELSF 243 Query: 358 QSKVGPLPWLQPYTDDAIKSYAKQGVKYMILVPIAFVNEHIETLHELDIEYCDEVAKEAG 537 QS+ GP WL+PYT ++ + KQ +++ P F + +ETL EL I + K+ G Sbjct: 244 QSRFGPKKWLEPYTTVKLEEFTKQNKSVVVIAP-GFSADCLETLEELAISEKENFIKKGG 302 >UniRef50_P28602 Cluster: Ferrochelatase; n=19; Proteobacteria|Rep: Ferrochelatase - Bradyrhizobium japonicum Length = 345 Score = 66.9 bits (156), Expect = 4e-10 Identities = 50/180 (27%), Positives = 80/180 (44%), Gaps = 1/180 (0%) Frame = +1 Query: 1 ERVVIFSQYPQYSCATTGSSLNAVADYYKNKQIPRDIRFSLIERWGSHPLLARVFAERIK 180 +R++ YPQYS +T+ + + V + +R + + A I+ Sbjct: 140 DRILAVPLYPQYSASTSATVCDEVFRVLARLRAQPTLRVT--PPYYEDEAYIEALAVSIE 197 Query: 181 EKLTLFPAGVRDQVLILFTAHSLPLKAVSRGDTYPHEVAASVSATVSELGA-VNPHRLVW 357 L P LI+ + H +P V +GD Y A+ A LG + L + Sbjct: 198 THLATLPFKPE---LIVASFHGMPKSYVDKGDPYQEHCIATTEALRRRLGVDASKLLLTF 254 Query: 358 QSKVGPLPWLQPYTDDAIKSYAKQGVKYMILVPIAFVNEHIETLHELDIEYCDEVAKEAG 537 QS+ G WLQPYTD ++ AK+GV+ + +V F + +ETL E+ E E+ K G Sbjct: 255 QSRFGNDEWLQPYTDKTMERLAKEGVRRIAVVTPGFAADCLETLEEIAQENA-EIFKHNG 313 >UniRef50_Q28VQ2 Cluster: Ferrochelatase; n=9; Rhodobacteraceae|Rep: Ferrochelatase - Jannaschia sp. (strain CCS1) Length = 370 Score = 66.5 bits (155), Expect = 5e-10 Identities = 51/180 (28%), Positives = 90/180 (50%), Gaps = 2/180 (1%) Frame = +1 Query: 4 RVVIFSQYPQYSCATTGSSLNAVADYYKNKQIPRDIRFSLIERWGSHPLLARVFAERIKE 183 +++ F YPQY+ AT+ ++ + +N + +R +E + ++PL A+ I+ Sbjct: 165 KILFFPLYPQYAGATSATACDQFFRSLENIKWQPQVR--TVEPYYANPLYIDALAQSIER 222 Query: 184 KLTLFPAGVRDQVLILFTAHSLPLKAVSRGDTYPHEVAASVSATVSELGAVNPHRLV--W 357 V+ +L+ + H +P + + GD Y H S + E + ++V + Sbjct: 223 AYAAMD--VKPDLLVT-SYHGVPKRYLMEGDPY-HCQCQKTSRLLKERLGWDDTQIVTTF 278 Query: 358 QSKVGPLPWLQPYTDDAIKSYAKQGVKYMILVPIAFVNEHIETLHELDIEYCDEVAKEAG 537 QSK GP WLQPYT + + A++G K + + AF + IETL E++ E E +EAG Sbjct: 279 QSKFGPEEWLQPYTVEEVARLAEKGKKRIAVCAPAFSADCIETLEEIN-EEIRESFEEAG 337 >UniRef50_A3TKF4 Cluster: Putative ferrochelatase; n=3; Bacteria|Rep: Putative ferrochelatase - Janibacter sp. HTCC2649 Length = 372 Score = 66.5 bits (155), Expect = 5e-10 Identities = 59/200 (29%), Positives = 87/200 (43%), Gaps = 14/200 (7%) Frame = +1 Query: 7 VVIFSQYPQYS-CATTGSSLNAVADYYKNKQIPRDIRFSLIERWGSHPLLARVFAERIKE 183 VV+ S Y YS C L A + + DI + + HP V E + + Sbjct: 116 VVVTSAYSSYSGCRQYREDLAAATEELGLAAVDLDI--DKVRPYALHPGFTAVNTEHLVD 173 Query: 184 KLTLFPAGVRDQVLILFTAHSLPLK-------AVSRGDTY--PHEVAASVSAT--VSELG 330 ++ A +LF HS+P S G+ Y H A + A G Sbjct: 174 SVSTIDASKLPTTRLLFVTHSIPEAMDDTSGPGDSDGNLYVEQHLRAGYLIAQGLTERTG 233 Query: 331 AVNPHRLVWQSKVGP--LPWLQPYTDDAIKSYAKQGVKYMILVPIAFVNEHIETLHELDI 504 P LV+ S+ G PWL+P +D I+ A +GV ++L PI FV++H+E +++LD Sbjct: 234 VTLPQELVFCSRSGSPRTPWLEPDVNDRIEELAAEGVTTVVLAPIGFVSDHMEVVNDLDR 293 Query: 505 EYCDEVAKEAGIVQIERAET 564 E E A G V+I R T Sbjct: 294 E-ARETADRLG-VEIVRVST 311 >UniRef50_Q82UK8 Cluster: Ferrochelatase; n=2; Betaproteobacteria|Rep: Ferrochelatase - Nitrosomonas europaea Length = 364 Score = 66.1 bits (154), Expect = 6e-10 Identities = 49/172 (28%), Positives = 89/172 (51%), Gaps = 3/172 (1%) Frame = +1 Query: 1 ERVVIFSQYPQYSCATTGSSLNAV-ADYYKNKQIPRDIRFSLIERWGSHPLLARVFAERI 177 +R+++ +PQY+ ++TG L+ V ++ K + IP DIR + + P A+ + Sbjct: 137 DRILVLPLFPQYAASSTGCVLDGVFSELRKMRNIP-DIR--TVRHYHDDPGYIAALAQNV 193 Query: 178 KEKLTLFPAGVRDQVLILFTAHSLPLKAVSRGDTYPHEVAAS--VSATVSELGAVNPHRL 351 ++ G D+++I F H +P K + GD Y E + + A EL A + +++ Sbjct: 194 RDYWEKH--GQPDKLIISF--HGVPRKTLEMGDPYHCECQKTGRLLAEALEL-ADDRYQI 248 Query: 352 VWQSKVGPLPWLQPYTDDAIKSYAKQGVKYMILVPIAFVNEHIETLHELDIE 507 +QS+ G WL PYT + + KQ + +V FV++ +ETL E+ +E Sbjct: 249 CFQSRFGFAQWLGPYTAEILAELGKQKTGRVDVVCPGFVSDCLETLEEIALE 300 >UniRef50_A3U6F4 Cluster: Ferrochelatase; n=14; Bacteroidetes|Rep: Ferrochelatase - Croceibacter atlanticus HTCC2559 Length = 354 Score = 65.7 bits (153), Expect = 8e-10 Identities = 53/200 (26%), Positives = 96/200 (48%), Gaps = 23/200 (11%) Frame = +1 Query: 7 VVIFSQYPQYSCATTGSSLNAVADYYKNKQIPRDIRFSLIERWGSHPLLARVFAERIKEK 186 +++ YPQ++ ATT ++ +A+ + ++ P+ ++ + + + + P V + IKEK Sbjct: 118 ILLVPLYPQFAMATT-ETIEVLAEKLRKEKFPQ-VKLTSLAPFYNKPDYIEVLSRSIKEK 175 Query: 187 LTLFPAGVRDQVLILFTAHSLPLKAVSRGDT----------------------YPHEVAA 300 L + +LF+ H +P + + + D Y H+ Sbjct: 176 LD-----TTNYDHLLFSYHGVPERHIRKSDITNSHCQIDGSCCKAQSDAHRFCYRHQCYE 230 Query: 301 SVSATVSELGAV-NPHRLVWQSKVGPLPWLQPYTDDAIKSYAKQGVKYMILVPIAFVNEH 477 + ELG +QS++G PWLQPYTD I+ K+G+K M +V AFV++ Sbjct: 231 TTRLVGEELGLKPGTFSTSFQSRLGFDPWLQPYTDRTIERMGKEGIKNMAIVTPAFVSDC 290 Query: 478 IETLHELDIEYCDEVAKEAG 537 +ETL E+ +E +E+ E G Sbjct: 291 LETLEEIAME-GEEIFHEVG 309 >UniRef50_Q88XC3 Cluster: Ferrochelatase; n=3; Lactobacillus|Rep: Ferrochelatase - Lactobacillus plantarum Length = 324 Score = 65.7 bits (153), Expect = 8e-10 Identities = 45/167 (26%), Positives = 83/167 (49%), Gaps = 2/167 (1%) Frame = +1 Query: 1 ERVVIFSQYPQYSCATTGSSLNAVADYYKNKQIPRDIRFSLIERWGSHPLLARVFAERIK 180 E+ +I +PQY+ +T G V + +P + I+ + P + A ++ Sbjct: 117 EKPIILPLFPQYTQSTHGGIHRQV----EATGLPH----TFIDSFYDQPTYIHLLATKVW 168 Query: 181 EKLTLFPAGVRDQVLILFTAHSLPLKAVSRGDTYPHEVAASVSATVSELGAVNPHRLV-- 354 + + A D V+ F+ HS+P V GD Y E A+ A ++E + +++ Sbjct: 169 QS---YQAHHYDAVI--FSYHSIPTAMVRHGDPYQRECEATTKAVLAERPELPADKVITA 223 Query: 355 WQSKVGPLPWLQPYTDDAIKSYAKQGVKYMILVPIAFVNEHIETLHE 495 +QSK GP+PWL+PY + + + G + +++V +FV + +ETL E Sbjct: 224 YQSKFGPMPWLKPYLKNELMQLVELGKRNVLVVTPSFVVDCLETLEE 270 >UniRef50_Q98H61 Cluster: Ferrochelatase; n=31; Alphaproteobacteria|Rep: Ferrochelatase - Rhizobium loti (Mesorhizobium loti) Length = 353 Score = 63.3 bits (147), Expect = 4e-09 Identities = 43/170 (25%), Positives = 76/170 (44%), Gaps = 1/170 (0%) Frame = +1 Query: 1 ERVVIFSQYPQYSCATTGSSLNAVADYYKNKQIPRDIRFSLIERWGSHPLLARVFAERIK 180 +R++ F YPQYS TT ++ + + + ++ R + + + P+ A I+ Sbjct: 148 DRILSFPLYPQYSATTTATANDQL--FRALMKLRRAPAIRSVPPYYAEPVYIEALASSIE 205 Query: 181 EKLTLFPAGVRDQVLILFTAHSLPLKAVSRGDTYPHEVAASVSATVSELGAVNPHRLV-W 357 L + +++ + H +P +GD Y + +LG + + Sbjct: 206 RHLATLDF---EPEVVITSYHGIPKPYSDKGDPYQAHCLETTRLLREKLGWDEKKLITTF 262 Query: 358 QSKVGPLPWLQPYTDDAIKSYAKQGVKYMILVPIAFVNEHIETLHELDIE 507 QS+ G WLQPYTD ++ K GVK + +V F + IETL E+ E Sbjct: 263 QSRFGAQEWLQPYTDKTVEKLGKDGVKSIAIVNPGFSVDCIETLDEIGRE 312 >UniRef50_A6DTB4 Cluster: Ferrochelatase; n=1; Lentisphaera araneosa HTCC2155|Rep: Ferrochelatase - Lentisphaera araneosa HTCC2155 Length = 807 Score = 61.7 bits (143), Expect = 1e-08 Identities = 49/181 (27%), Positives = 83/181 (45%), Gaps = 2/181 (1%) Frame = +1 Query: 1 ERVVIFSQYPQYSCATTGSSLNAVADYYKNKQIPRDIRFSLIERWGSHPLLARVFAERIK 180 E + + +PQY ATT S + + ++I F +E + + P A I Sbjct: 120 ETIRVIPLFPQYCEATTLSCKDMLEKGIAEHGKCKNIEF--VEDFHNSPSYINNVARLIS 177 Query: 181 EKLTLFPAGVRDQVLILFTAHSLPLKAVSRGDTYPHEVAASVSATVSELGAVNPHR--LV 354 E L P +LF+ H P++ V GD Y + + ++ ++ L Sbjct: 178 EDLATNPPEK-----LLFSFHGYPIRRVRGGDPYFAQCTETGHLIADQVTGIDKENILLT 232 Query: 355 WQSKVGPLPWLQPYTDDAIKSYAKQGVKYMILVPIAFVNEHIETLHELDIEYCDEVAKEA 534 +QSK G PWL P T++ + A +G+K + + AFV +++ETL E+ I +E+ E Sbjct: 233 FQSKFGREPWLTPGTEETLIELAHKGIKNVAVTCPAFVVDNLETLEEVGIG-LEEIFLEH 291 Query: 535 G 537 G Sbjct: 292 G 292 >UniRef50_Q6AB01 Cluster: Ferrochelatase, HemH; n=1; Propionibacterium acnes|Rep: Ferrochelatase, HemH - Propionibacterium acnes Length = 683 Score = 61.3 bits (142), Expect = 2e-08 Identities = 49/172 (28%), Positives = 82/172 (47%), Gaps = 12/172 (6%) Frame = +1 Query: 106 DIRFSLIERWGSHPLLARVFAERIKEKLTLFPAGVRDQVLILFTAHSLPLK------AVS 267 D++ + + P R AE + + P + ++F HS+P A Sbjct: 148 DMQVDKVPPFNEAPGFIRANAEALMQAFMRIPPTPLEATRVVFVTHSIPDSMQDASGAGQ 207 Query: 268 RGDTY--PHE-VAASVSATVSEL-GAVNPHRLVWQSKVG-PL-PWLQPYTDDAIKSYAKQ 429 G Y H+ V V+ V ++ G + L + S+ G P PWL+P D ++S +Q Sbjct: 208 PGTDYISQHKAVCERVAGQVRQVFGNMPQWDLAYCSRSGRPSDPWLEPDIIDHLRSLPEQ 267 Query: 430 GVKYMILVPIAFVNEHIETLHELDIEYCDEVAKEAGIVQIERAETPEHSSHI 585 GV+ +++ PI FV +H+E +++LD E E AKE+G+ A HS+ I Sbjct: 268 GVQSVVVAPIGFVADHMEVVNDLDYE-AAEAAKESGLAFTRAATAGTHSAFI 318 >UniRef50_Q8XW32 Cluster: Ferrochelatase; n=17; Proteobacteria|Rep: Ferrochelatase - Ralstonia solanacearum (Pseudomonas solanacearum) Length = 371 Score = 58.8 bits (136), Expect = 9e-08 Identities = 42/173 (24%), Positives = 77/173 (44%), Gaps = 4/173 (2%) Frame = +1 Query: 1 ERVVIFSQYPQYSCATTGSSLNAVADYYKNKQIPRDIRFSLIERWGSHPLLARVFAERIK 180 ER+++ YPQYS TT ++ + V + ++R L++ + HP +++ Sbjct: 139 ERILVLPMYPQYSGTTTATAFDEVFRVMGQMRNQPELR--LVKHFHDHPAYINALHQQVG 196 Query: 181 EKLTLF--PAGVRDQVLILFTAHSLPLKAVSRGDTYPHEVAASVSATVSELGAVNP--HR 348 P R L+L + H +P + + GD Y H + E + P + Sbjct: 197 AYWAQHGAPDFARGDKLLL-SFHGVPRRTLELGDPY-HCACLKTGRLLGEALGLQPGQYL 254 Query: 349 LVWQSKVGPLPWLQPYTDDAIKSYAKQGVKYMILVPIAFVNEHIETLHELDIE 507 + +QS+ G WLQPYT ++ + G + + F + +ETL E+ +E Sbjct: 255 VTFQSRFGRAEWLQPYTAPTLEELGRVGTGRVDVFCPGFPADCLETLEEIAME 307 >UniRef50_P72183 Cluster: Ferrochelatase; n=1; Propionibacterium freudenreichii subsp. freudenreichii|Rep: Ferrochelatase - Propionibacterium freudenreichii subsp. freudenreichii Length = 352 Score = 58.4 bits (135), Expect = 1e-07 Identities = 35/112 (31%), Positives = 58/112 (51%), Gaps = 9/112 (8%) Frame = +1 Query: 226 ILFTAHSLPLKAVS----RGDTYPHEVAASVSATVSELGAVNPH---RLVWQSKVGP--L 378 ++FT HS+P G+ Y + A + A ++EL A+ L +QS+ G Sbjct: 173 LVFTTHSIPTAMAETSGPHGNAYIPQHLALIDAVMAELAALGLRPSWELAYQSRSGSPRT 232 Query: 379 PWLQPYTDDAIKSYAKQGVKYMILVPIAFVNEHIETLHELDIEYCDEVAKEA 534 PWL+P +D I A +GV+ +I PI F+ +H+E + +LD E A+ + Sbjct: 233 PWLEPDINDVITRLAGEGVRDVICSPIGFLTDHMEVVWDLDTEAAATAAEHS 284 >UniRef50_P57779 Cluster: Ferrochelatase; n=9; Bacteria|Rep: Ferrochelatase - Zymomonas mobilis Length = 334 Score = 57.2 bits (132), Expect = 3e-07 Identities = 40/168 (23%), Positives = 79/168 (47%) Frame = +1 Query: 4 RVVIFSQYPQYSCATTGSSLNAVADYYKNKQIPRDIRFSLIERWGSHPLLARVFAERIKE 183 R+++ YPQYS A+T + + Y + + ++R +E + +HP + + I++ Sbjct: 129 RILLAPLYPQYSAASTATVQDEAYRYLQKIRWQPNLR--SLEPYYTHPAYIQTLKKNIED 186 Query: 184 KLTLFPAGVRDQVLILFTAHSLPLKAVSRGDTYPHEVAASVSATVSELGAVNPHRLVWQS 363 ++ D +L+ + H +P+K GD Y + A+ A S L P +QS Sbjct: 187 QIKALDF-KPDSLLLSY--HGMPVKTRELGDPYYFQCQATSQALSSLLDI--PVITSFQS 241 Query: 364 KVGPLPWLQPYTDDAIKSYAKQGVKYMILVPIAFVNEHIETLHELDIE 507 + G W P TD +K + ++ + + F + +ETL E+ ++ Sbjct: 242 RFGSQKWFTPATDMTLKELPSKNIRNLAVAMPGFSADCLETLEEIALQ 289 >UniRef50_Q5ZYE7 Cluster: Ferrochelatase; n=5; Legionella pneumophila|Rep: Ferrochelatase - Legionella pneumophila subsp. pneumophila (strain Philadelphia 1 /ATCC 33152 / DSM 7513) Length = 331 Score = 56.4 bits (130), Expect = 5e-07 Identities = 46/197 (23%), Positives = 89/197 (45%), Gaps = 20/197 (10%) Frame = +1 Query: 7 VVIFSQYPQYSCATTGSSLNAVADYYKNKQIPRDIRFSLIERWGSHPLLARVFAERIKEK 186 + I +PQYS A TGS++ + N++I I+ +I + P E I+ + Sbjct: 118 LTILPLFPQYSSAATGSAIEKTLSHLANQEIIPSIK--IIRDFYQRP-------EYIQAQ 168 Query: 187 LTLFPAGVRDQVLILFTAHSLPLKAVSRG--DTYPHEVAASVS----------------- 309 + ++D +LF+ H +P + + + DT + + Sbjct: 169 AKIMKPYIKDNFHLLFSYHGIPERHIHKSGCDTLCPQTCTPIYDKNQACYRAQCYQTSLL 228 Query: 310 -ATVSELGAVNPHRLVWQSKVGPLPWLQPYTDDAIKSYAKQGVKYMILVPIAFVNEHIET 486 A +LG + + +QS++G PW++PYTD+ +G+K +++ +FV + +ET Sbjct: 229 LAKELQLGT-HQYTTAFQSRLGKTPWIKPYTDEIFAELISKGIKNIVVSCPSFVADCLET 287 Query: 487 LHELDIEYCDEVAKEAG 537 L E+ I ++ K G Sbjct: 288 LEEIGIRAKEQWEKLGG 304 >UniRef50_A0L8B7 Cluster: Ferrochelatase; n=1; Magnetococcus sp. MC-1|Rep: Ferrochelatase - Magnetococcus sp. (strain MC-1) Length = 335 Score = 54.8 bits (126), Expect = 2e-06 Identities = 28/92 (30%), Positives = 47/92 (51%), Gaps = 1/92 (1%) Frame = +1 Query: 226 ILFTAHSLPLKAVSRGDTYPHEVAASVSATVSELGAVNPHRLV-WQSKVGPLPWLQPYTD 402 +L + H LP + V GD Y + + EL + ++ +QS+ G PWL+P TD Sbjct: 194 LLLSYHGLPKRHVDEGDPYENHCQTTTLLLTEELDLRHDQWMMSYQSRFGSEPWLEPNTD 253 Query: 403 DAIKSYAKQGVKYMILVPIAFVNEHIETLHEL 498 K+ QG+K + ++ F + +ETL E+ Sbjct: 254 MLFKTLPSQGIKKLTVMCPGFAADCLETLEEI 285 >UniRef50_A5V0K6 Cluster: Ferrochelatase; n=2; Roseiflexus|Rep: Ferrochelatase - Roseiflexus sp. RS-1 Length = 314 Score = 54.4 bits (125), Expect = 2e-06 Identities = 36/144 (25%), Positives = 61/144 (42%) Frame = +1 Query: 94 QIPRDIRFSLIERWGSHPLLARVFAERIKEKLTLFPAGVRDQVLILFTAHSLPLKAVSRG 273 ++ + +R LI W P L P R + +L AHS+ A Sbjct: 137 EVAQPVRLHLIPDWPDLPGYRSALTINATLALERLPDCDRSRTALLAIAHSVAESARKPE 196 Query: 274 DTYPHEVAASVSATVSELGAVNPHRLVWQSKVGPLPWLQPYTDDAIKSYAKQGVKYMILV 453 Y + ++ VS LG + L + GP WL P A+ A+ G+++++ V Sbjct: 197 TEYQWRLRQTMQRLVSTLGCGAGY-LAYYGAGGPGQWLGPDVLSALDEIARAGLRHVLAV 255 Query: 454 PIAFVNEHIETLHELDIEYCDEVA 525 PI V +++E +ELD+ + A Sbjct: 256 PINTVYDNVEVCYELDVRMAERAA 279 >UniRef50_Q4JSM9 Cluster: Ferrochelatase; n=1; Corynebacterium jeikeium K411|Rep: Ferrochelatase - Corynebacterium jeikeium (strain K411) Length = 424 Score = 53.2 bits (122), Expect = 5e-06 Identities = 31/76 (40%), Positives = 46/76 (60%), Gaps = 3/76 (3%) Frame = +1 Query: 349 LVWQSKVGP--LPWLQPYTDDAIKSYAKQG-VKYMILVPIAFVNEHIETLHELDIEYCDE 519 LVWQS+ G +PWL+P D I++ A+ G + ++L P+ F+ +H+E +LD E D Sbjct: 285 LVWQSRSGSPHVPWLEPDVCDHIEARAEAGNTRAIVLCPVGFITDHMEVKWDLDTEARDA 344 Query: 520 VAKEAGIVQIERAETP 567 AK AGI + R TP Sbjct: 345 AAK-AGIPFV-RVATP 358 >UniRef50_A7BBG3 Cluster: Putative uncharacterized protein; n=1; Actinomyces odontolyticus ATCC 17982|Rep: Putative uncharacterized protein - Actinomyces odontolyticus ATCC 17982 Length = 347 Score = 52.8 bits (121), Expect = 6e-06 Identities = 50/182 (27%), Positives = 82/182 (45%), Gaps = 4/182 (2%) Frame = +1 Query: 4 RVVIFSQYPQYSCATTGSSLNAVADYYKNKQIPRDIRFSLIERWGSHPLLARVFA---ER 174 RV I YPQY+ +T + +AVA + + ++R L + + P A ER Sbjct: 139 RVAILPAYPQYAASTVTTINDAVAQWIGRNRDGFELR--LHRSFPAAPAYIEALATALER 196 Query: 175 IKEKLTLFPAGVRDQVLILFTAHSLPLKAVSRGDTYPHEVAASVSATVSELG-AVNPHRL 351 E++ D++++ F HS+P+ GD Y E +V+A S LG A+ Sbjct: 197 HWERVGRPNFLTGDRIVVSF--HSIPVAMDEAGDPYRAECRHTVAALESRLGLAMGSLTA 254 Query: 352 VWQSKVGPLPWLQPYTDDAIKSYAKQGVKYMILVPIAFVNEHIETLHELDIEYCDEVAKE 531 +QS G WL P T + + + ++ F+ + +ETL E+D + E E Sbjct: 255 TFQSVFGRAEWLGPQTIEEMAELGAAKCPRVDVICPGFMADCLETLEEID-QLNRETFVE 313 Query: 532 AG 537 AG Sbjct: 314 AG 315 >UniRef50_Q1DC34 Cluster: Ferrochelatase; n=3; Myxococcales|Rep: Ferrochelatase - Myxococcus xanthus (strain DK 1622) Length = 364 Score = 50.8 bits (116), Expect = 2e-05 Identities = 22/61 (36%), Positives = 39/61 (63%) Frame = +1 Query: 355 WQSKVGPLPWLQPYTDDAIKSYAKQGVKYMILVPIAFVNEHIETLHELDIEYCDEVAKEA 534 +QS++G PW++PYTD + AK+GVK + ++ AFV + +ETL E+ + ++ + Sbjct: 257 FQSRLGRTPWVKPYTDVVLPELAKKGVKRLAVMCPAFVADCLETLEEIGLRAREQFLEAG 316 Query: 535 G 537 G Sbjct: 317 G 317 >UniRef50_Q9K097 Cluster: Ferrochelatase; n=5; Neisseria|Rep: Ferrochelatase - Neisseria meningitidis serogroup B Length = 336 Score = 50.8 bits (116), Expect = 2e-05 Identities = 36/166 (21%), Positives = 74/166 (44%), Gaps = 1/166 (0%) Frame = +1 Query: 4 RVVIFSQYPQYSCATTGSSLNAVADYYKNKQIPRDIRFSLIERWGSHPLLARVFAERIKE 183 R+++ YPQY+ +++G++++ V + ++ +R + R+ + + +K Sbjct: 133 RLLVIPMYPQYAASSSGAAVDKVCEQLLLQRNQMSVR--TVSRFYDDT----GYIDAMKN 186 Query: 184 KLTLFPAGVRDQVLILFTAHSLPLKAVSRGDTYPHEVAASVSATVSELGAVNPHRLV-WQ 360 + + A ++ + H +P K GD YP E + L +V +Q Sbjct: 187 HILRYWAEHGRGKKLMLSFHGVPQKHHDLGDPYPDECRHTAKLLAEALELTEDQYVVSFQ 246 Query: 361 SKVGPLPWLQPYTDDAIKSYAKQGVKYMILVPIAFVNEHIETLHEL 498 S+ G W+ P T D KQGV + + F+ + +ET+ E+ Sbjct: 247 SQFGRAKWVTPSTQDLFGKLPKQGVTELDVFCPGFLADCLETMEEI 292 >UniRef50_Q4QE43 Cluster: Ferrochelatase-like protein; n=21; Leishmania|Rep: Ferrochelatase-like protein - Leishmania major Length = 385 Score = 46.8 bits (106), Expect = 4e-04 Identities = 39/158 (24%), Positives = 67/158 (42%), Gaps = 20/158 (12%) Frame = +1 Query: 7 VVIFSQYPQYSCATTGSSLNAVADYYKNKQIPRDIRFSLIERWGSHPL----LARVFAER 174 +V+ +PQY+ T+ S + V +Y + Q I + HP+ L Sbjct: 143 LVVLPLFPQYTSTTSASIYDEVFKFYTDTQRRSIPSLRTIRDYAEHPVYVEALGSSLLSS 202 Query: 175 IKEKLTLFPAGVRD----------QVLILFTAHSLPLKAVSRGDTYPHEVAASVSATVSE 324 IK +T +D ++ I+ T HS+P++ V D YP A+ +A + Sbjct: 203 IKAHVTAKAGAAKDWKSALADQLPEIGIIITYHSIPVRYVEEHDDYPQRCEATTAAIKAY 262 Query: 325 LGAVNPHRL------VWQSKVGPLPWLQPYTDDAIKSY 420 + A + L V+QS+ G PWL P + A ++ Sbjct: 263 IEAESGISLSDCLVHVYQSQFGNQPWLGPTLNAAATAF 300 >UniRef50_Q6L0G9 Cluster: Ferrochelatase; n=2; Thermoplasmatales|Rep: Ferrochelatase - Picrophilus torridus Length = 287 Score = 46.8 bits (106), Expect = 4e-04 Identities = 37/116 (31%), Positives = 60/116 (51%) Frame = +1 Query: 229 LFTAHSLPLKAVSRGDTYPHEVAASVSATVSELGAVNPHRLVWQSKVGPLPWLQPYTDDA 408 LF AHSLPL S TY + + + + +S + + + S+ WL P D Sbjct: 163 LFAAHSLPL--YSDESTYENLII-NTARRLSNTFLKDDYFYGFYSQGEHGKWLYPSIYDY 219 Query: 409 IKSYAKQGVKYMILVPIAFVNEHIETLHELDIEYCDEVAKEAGIVQIERAETPEHS 576 I + + ++PI F+ EH+E L++LDIE+ +++ K+ GI +R ETP S Sbjct: 220 IDKLKEYNS--VTVIPIGFIYEHLEILYDLDIEFKNKL-KDYGI-SYDRVETPSCS 271 >UniRef50_Q9HVD7 Cluster: Ferrochelatase; n=19; Pseudomonadaceae|Rep: Ferrochelatase - Pseudomonas aeruginosa Length = 340 Score = 46.0 bits (104), Expect = 7e-04 Identities = 20/61 (32%), Positives = 37/61 (60%) Frame = +1 Query: 355 WQSKVGPLPWLQPYTDDAIKSYAKQGVKYMILVPIAFVNEHIETLHELDIEYCDEVAKEA 534 +QS++G W++PYTD + ++GVK ++++ AFV + IETL E+ + ++ Sbjct: 250 FQSRLGRAKWIEPYTDAKLDELVQRGVKRLLVMCPAFVADCIETLEEIGMRGREQFISAG 309 Query: 535 G 537 G Sbjct: 310 G 310 >UniRef50_Q6MHT3 Cluster: Ferrochelatase; n=1; Bdellovibrio bacteriovorus|Rep: Ferrochelatase - Bdellovibrio bacteriovorus Length = 335 Score = 46.0 bits (104), Expect = 7e-04 Identities = 25/76 (32%), Positives = 42/76 (55%), Gaps = 1/76 (1%) Frame = +1 Query: 280 YPHEVAASVSATVSELGAVNPH-RLVWQSKVGPLPWLQPYTDDAIKSYAKQGVKYMILVP 456 Y + A+ +A L H + +QS++G WL+P TD +++ AK G K + ++ Sbjct: 223 YRAQCFATATAIAESLNLAPSHWSVAFQSRLGRAEWLKPATDHSLEVLAKTGKKNIAVIC 282 Query: 457 IAFVNEHIETLHELDI 504 +FV + IETL E+ I Sbjct: 283 PSFVADCIETLEEIGI 298 >UniRef50_Q83FA4 Cluster: Ferrochelatase; n=4; Coxiella burnetii|Rep: Ferrochelatase - Coxiella burnetii Length = 343 Score = 44.0 bits (99), Expect = 0.003 Identities = 18/52 (34%), Positives = 35/52 (67%) Frame = +1 Query: 349 LVWQSKVGPLPWLQPYTDDAIKSYAKQGVKYMILVPIAFVNEHIETLHELDI 504 + +QS++G W++PYTD + +K+G+K +++V +F + +ETL E+ I Sbjct: 251 VAFQSRLGRAKWIEPYTDKYLIELSKKGIKKLMVVCPSFPVDCLETLEEIGI 302 >UniRef50_Q8YNF0 Cluster: Alr4616 protein; n=9; Cyanobacteria|Rep: Alr4616 protein - Anabaena sp. (strain PCC 7120) Length = 349 Score = 43.2 bits (97), Expect = 0.005 Identities = 41/159 (25%), Positives = 71/159 (44%), Gaps = 6/159 (3%) Frame = +1 Query: 139 SHPLLARVFAERIKEKLT--LFPAGVRDQVLILFTAHSLPLKAVSRGDTYPHEVAASVSA 312 + P + A ++EK+ L A + Q+ I+ H P KA +G T + ++ Sbjct: 163 NEPEYIHLMAHLVEEKINADLATAYLPSQIGIVLMNHGCPHKA--KGFTSGIVESQALYD 220 Query: 313 TVSELGAVNPHRLV---WQSKVGPL-PWLQPYTDDAIKSYAKQGVKYMILVPIAFVNEHI 480 V E + + L+ W + PL W QP + A K+ + G K +I +PI F E+ Sbjct: 221 LVRE-ELIYKYPLISVGWLNHDTPLIEWTQPNAEQAAKNLIQLGAKVIIFMPIGFATENH 279 Query: 481 ETLHELDIEYCDEVAKEAGIVQIERAETPEHSSHIHSGA 597 ETL ++ D K +G+ ++ A +H + A Sbjct: 280 ETLLDVHHIIHDLEKKYSGVDYVQMACVNDHPEFLAMAA 318 >UniRef50_Q8EY34 Cluster: Ferrochelatase; n=5; Leptospira|Rep: Ferrochelatase - Leptospira interrogans Length = 98 Score = 41.9 bits (94), Expect = 0.012 Identities = 20/53 (37%), Positives = 34/53 (64%) Frame = +1 Query: 409 IKSYAKQGVKYMILVPIAFVNEHIETLHELDIEYCDEVAKEAGIVQIERAETP 567 ++ K+GVK + + PI+FV++H+ETL E+ E +VA + GI++ R P Sbjct: 2 LEDLGKKGVKRVAVYPISFVSDHLETLEEIG-EQLKKVAYQNGILEYYRIPAP 53 >UniRef50_A7BEQ8 Cluster: Putative uncharacterized protein; n=1; Actinomyces odontolyticus ATCC 17982|Rep: Putative uncharacterized protein - Actinomyces odontolyticus ATCC 17982 Length = 734 Score = 41.5 bits (93), Expect = 0.015 Identities = 27/76 (35%), Positives = 43/76 (56%), Gaps = 4/76 (5%) Frame = +1 Query: 349 LVWQSKVGPLP--WLQPYTDDAIKSYAKQG--VKYMILVPIAFVNEHIETLHELDIEYCD 516 LV+ S+ GP WL+P +D ++ A + ++VPI F+ +H+E +++LD E Sbjct: 279 LVYCSRSGPPQSRWLEPDINDFLEEIAADANPLTGAVVVPIGFICDHMEVVYDLDTE-AK 337 Query: 517 EVAKEAGIVQIERAET 564 E A GI ERA+T Sbjct: 338 ETAARLGI-PYERADT 352 >UniRef50_Q9HLB8 Cluster: Ferrochelatase; n=2; Thermoplasma|Rep: Ferrochelatase - Thermoplasma acidophilum Length = 308 Score = 39.5 bits (88), Expect = 0.062 Identities = 34/117 (29%), Positives = 57/117 (48%) Frame = +1 Query: 229 LFTAHSLPLKAVSRGDTYPHEVAASVSATVSELGAVNPHRLVWQSKVGPLPWLQPYTDDA 408 LF AHSLP A R + Y + S + +S++ ++ +Q G L WL P D Sbjct: 163 LFDAHSLP--APDREEDYLFWLRYS-TYKISQILGLSRSDFGFQG--GHLGWLGPSIYDV 217 Query: 409 IKSYAKQGVKYMILVPIAFVNEHIETLHELDIEYCDEVAKEAGIVQIERAETPEHSS 579 + + + ++PI+F+ +H+E L++LD E+ A EA + R P S+ Sbjct: 218 LN---RIDASKITVIPISFLYDHLEILYDLDYEF--RKAVEAKGMHYRRVRMPNDSA 269 >UniRef50_Q7MXP4 Cluster: Ferrochelatase; n=1; Porphyromonas gingivalis|Rep: Ferrochelatase - Porphyromonas gingivalis (Bacteroides gingivalis) Length = 345 Score = 39.1 bits (87), Expect = 0.081 Identities = 18/62 (29%), Positives = 39/62 (62%) Frame = +1 Query: 352 VWQSKVGPLPWLQPYTDDAIKSYAKQGVKYMILVPIAFVNEHIETLHELDIEYCDEVAKE 531 V+QS+VG WL+PY + + ++ ++ K +++ +FV + +E+L E+ ++ + K+ Sbjct: 259 VFQSRVGHTEWLRPYLIERLSAWPQEETKRILIACPSFVCDCLESLEEV-ADHGQSIFKK 317 Query: 532 AG 537 AG Sbjct: 318 AG 319 >UniRef50_Q97UK4 Cluster: Putative uncharacterized protein; n=1; Sulfolobus solfataricus|Rep: Putative uncharacterized protein - Sulfolobus solfataricus Length = 597 Score = 36.3 bits (80), Expect = 0.57 Identities = 27/98 (27%), Positives = 47/98 (47%), Gaps = 2/98 (2%) Frame = +1 Query: 259 AVSRGDTYPHEVAASVSATVSELGAVNPHRLVWQSKVGPLPWLQPYTDDAIKSYAKQGVK 438 A SRG P V + V +LG N + ++ K + + ++ + AK+G Sbjct: 439 AGSRGVKIPERVRLLENNLVLDLGQTNMYTYSFKEKDAKVIGIDENSNIGVAFLAKRGKG 498 Query: 439 YMIL--VPIAFVNEHIETLHELDIEYCDEVAKEAGIVQ 546 +IL VP+ ++ + ET+ E I + + +AK A I Q Sbjct: 499 NVILSTVPLELISSNYETMKENRISFYNYLAKIANIEQ 536 >UniRef50_Q9PBW1 Cluster: Putative uncharacterized protein; n=5; Xylella fastidiosa|Rep: Putative uncharacterized protein - Xylella fastidiosa Length = 332 Score = 35.9 bits (79), Expect = 0.76 Identities = 23/82 (28%), Positives = 36/82 (43%), Gaps = 2/82 (2%) Frame = +1 Query: 352 VWQSKVGPLPWLQP--YTDDAIKSYAKQGVKYMILVPIAFVNEHIETLHELDIEYCDEVA 525 VW +V PL WL P + I A + Y+++ + + + TL L I + +V Sbjct: 90 VWSERVSPLSWLGPRRWNSPGIDFNALPPIDYVLITHNHYDHLDLTTLARLQIAHAPQVV 149 Query: 526 KEAGIVQIERAETPEHSSHIHS 591 G I R P+ HIH+ Sbjct: 150 TPLGNDAIIRKRVPD--LHIHT 169 >UniRef50_Q11W64 Cluster: CHU large protein; candidate b-glycosidase, glycoside hydrolase family 8 protein; n=1; Cytophaga hutchinsonii ATCC 33406|Rep: CHU large protein; candidate b-glycosidase, glycoside hydrolase family 8 protein - Cytophaga hutchinsonii (strain ATCC 33406 / NCIMB 9469) Length = 2690 Score = 35.5 bits (78), Expect = 1.0 Identities = 33/105 (31%), Positives = 44/105 (41%), Gaps = 2/105 (1%) Frame = -2 Query: 464 NAIGTRIIYFTPCFAYDLMASSV*GCSHGRGPTFDCQTSLWGFTAPSSLTVAD-TDAATS 288 NA T + TP S + G P F S+ G AP+ L V D T TS Sbjct: 1963 NATATFTVTGTPALVGANTGSITIASNDGTTPAFKINVSVTGTAAPAKLQVVDGTSILTS 2022 Query: 287 CGYVSPLDTAFRGRLCAVKSIRT*SLTPAGNS-VSFSFILSANTL 156 G L TA G AV T S+ G S ++F+ I S++ + Sbjct: 2023 NGTAISLGTAVVG--SAVPDYTTISIKNTGGSPLTFTSITSSSAV 2065 >UniRef50_Q1GGC1 Cluster: 3-hydroxyacyl-CoA dehydrogenase NAD-binding; n=4; Alphaproteobacteria|Rep: 3-hydroxyacyl-CoA dehydrogenase NAD-binding - Silicibacter sp. (strain TM1040) Length = 733 Score = 34.7 bits (76), Expect = 1.8 Identities = 14/28 (50%), Positives = 17/28 (60%) Frame = +3 Query: 483 DITRTGHRILRRSRQRGWNRTNRKGGNP 566 D T GHRILR+ + G + N KGG P Sbjct: 87 DFTMNGHRILRKLERAGMDAKNNKGGKP 114 >UniRef50_UPI0001555B1E Cluster: PREDICTED: similar to Transmembrane protein 79; n=1; Ornithorhynchus anatinus|Rep: PREDICTED: similar to Transmembrane protein 79 - Ornithorhynchus anatinus Length = 342 Score = 34.3 bits (75), Expect = 2.3 Identities = 16/42 (38%), Positives = 22/42 (52%) Frame = +2 Query: 326 WER*TPTGSSGNRRWDLCRGCSPTPTMPSSHTQNKG*NI*FW 451 WE TG S R+W+ G +P P +P S T +KG +W Sbjct: 153 WE--AATGGSPGRKWEAAAGGTPMPALPVSITGSKGXXXXWW 192 >UniRef50_Q8I5I1 Cluster: Putative uncharacterized protein; n=1; Plasmodium falciparum 3D7|Rep: Putative uncharacterized protein - Plasmodium falciparum (isolate 3D7) Length = 1560 Score = 34.3 bits (75), Expect = 2.3 Identities = 18/71 (25%), Positives = 39/71 (54%), Gaps = 7/71 (9%) Frame = -1 Query: 267 RHSLQREAVCSEEYQN---LISYTGWEQCKFFLYPLSEYPRK----EGVGTPTFYQTKPY 109 +++ Q + +E+Y N +++Y W++C +++Y + +Y RK EG+ + Y Sbjct: 1223 KNTKQNKTNINEKYNNNNIIMNYLTWKKCLYYIYKIKKYTRKIETHEGLYISSMLYINIY 1282 Query: 108 IPRDLFILVVI 76 + + FIL+ I Sbjct: 1283 LCQIFFILLNI 1293 >UniRef50_Q64SD9 Cluster: Putative uncharacterized protein; n=1; Bacteroides fragilis|Rep: Putative uncharacterized protein - Bacteroides fragilis Length = 313 Score = 33.9 bits (74), Expect = 3.1 Identities = 26/92 (28%), Positives = 47/92 (51%), Gaps = 3/92 (3%) Frame = +1 Query: 274 DTYPHEVAASVSATVSELGAVNPHRLVWQSKVGPLPWLQPYTDDAIKSYAKQGVKYMILV 453 D + +EV + V++ A+ RL+W+ +G L TD + +Y K G KY+I + Sbjct: 44 DNFHYEVNERLELLVNDTAAIKGKRLIWE--MGNGDTLMRNTDVSY-TYRKAG-KYLITL 99 Query: 454 PI---AFVNEHIETLHELDIEYCDEVAKEAGI 540 I VN++I+ + L+ E D + + G+ Sbjct: 100 KIDGKHSVNKYIKVISGLEHEAIDSIPRINGV 131 >UniRef50_A3PTJ5 Cluster: NAD-dependent epimerase/dehydratase; n=3; Mycobacterium|Rep: NAD-dependent epimerase/dehydratase - Mycobacterium sp. (strain JLS) Length = 466 Score = 33.9 bits (74), Expect = 3.1 Identities = 21/53 (39%), Positives = 28/53 (52%), Gaps = 2/53 (3%) Frame = -2 Query: 278 VSPLDTAFRGRLCAVKSIRT*SLTPAGNSVSFSFILSANTLARR--GWEPQRS 126 VS A R + A+ ++R +LTP V+F L + ARR GWEP RS Sbjct: 265 VSVPPQAVRTLIAALSAVRVVALTPGWYDVAFKTPLMDTSKARRTLGWEPARS 317 >UniRef50_Q4QGN5 Cluster: Putative uncharacterized protein; n=3; Leishmania|Rep: Putative uncharacterized protein - Leishmania major Length = 1874 Score = 33.1 bits (72), Expect = 5.3 Identities = 21/50 (42%), Positives = 28/50 (56%), Gaps = 5/50 (10%) Frame = +3 Query: 330 SGEPPQ----ARL-AIEGGTSAVAAALHRRCHQVIRKTRGEIYDSGPDSV 464 SG PPQ ARL A+ GG +AAAL ++ V+R+ R E D + V Sbjct: 1319 SGSPPQGNNDARLMAVTGGDDGLAAALRKKHKVVVRRGRDEENDGDAEEV 1368 >UniRef50_A6RAS7 Cluster: Putative uncharacterized protein; n=1; Ajellomyces capsulatus NAm1|Rep: Putative uncharacterized protein - Ajellomyces capsulatus NAm1 Length = 320 Score = 33.1 bits (72), Expect = 5.3 Identities = 12/34 (35%), Positives = 20/34 (58%) Frame = -3 Query: 610 DDVCKRRYEYGMSVRGFPPFLFVRFQPLWRLRRS 509 +D+ Y+ G V+ PPF+ +FQ LW L+ + Sbjct: 250 EDIVAYDYQLGRKVKMLPPFMMDQFQTLWELQEA 283 >UniRef50_Q9A450 Cluster: Sensor protein; n=1; Caulobacter vibrioides|Rep: Sensor protein - Caulobacter crescentus (Caulobacter vibrioides) Length = 624 Score = 32.7 bits (71), Expect = 7.1 Identities = 32/99 (32%), Positives = 48/99 (48%), Gaps = 2/99 (2%) Frame = +1 Query: 103 RDIRFSLIERWGSHPLLARVFAERIKEKLT--LFPAGVRDQVLILFTAHSLPLKAVSRGD 276 R+ R + +ER S LLAR AE I E T L+ G R ++L L L+A +R D Sbjct: 19 REARIARLERRLSRELLARREAEAIAEAATHRLYRQGERMRLLA-----DLALEA-NRSD 72 Query: 277 TYPHEVAASVSATVSELGAVNPHRLVWQSKVGPLPWLQP 393 + A++ A S+ G H + ++ + WLQP Sbjct: 73 DLDTVLRAALRAIGSQTGWPVGHVQLVETDAEAMDWLQP 111 >UniRef50_A6TNA9 Cluster: ABC transporter related; n=1; Alkaliphilus metalliredigens QYMF|Rep: ABC transporter related - Alkaliphilus metalliredigens QYMF Length = 284 Score = 32.7 bits (71), Expect = 7.1 Identities = 26/82 (31%), Positives = 40/82 (48%), Gaps = 4/82 (4%) Frame = +1 Query: 1 ERVVIFSQYPQ-YSCATTGSSLNAVADYYKNKQIPRDIRFSLIERWGSHP---LLARVFA 168 ER+ + +P Y T +L VA YY+NK PR+I L++R G P F+ Sbjct: 76 ERIGVAFDFPNLYLKLTAAENLQLVAAYYQNK--PRNIEV-LLDRVGLLPDRDKKVEAFS 132 Query: 169 ERIKEKLTLFPAGVRDQVLILF 234 + +K +L A + D L+ F Sbjct: 133 KGMKMRLNFIRAILHDPELLFF 154 >UniRef50_A7CYB9 Cluster: Ethanolamine ammonia-lyase large subunit-like protein; n=1; Opitutaceae bacterium TAV2|Rep: Ethanolamine ammonia-lyase large subunit-like protein - Opitutaceae bacterium TAV2 Length = 308 Score = 32.3 bits (70), Expect = 9.3 Identities = 27/87 (31%), Positives = 39/87 (44%), Gaps = 4/87 (4%) Frame = +3 Query: 321 RAGSGEPPQARLAIEGGTSA--VAAALHRRCHQVIRKTRGEIYDSGPDSVCQRTHRDITR 494 RA +PP R A A + L RRCH+ R +D + +RTH + R Sbjct: 19 RAPPAQPPDRRPARHRRLHARWTSLRLRRRCHRHQPGHRQRTHDGSAPAPDRRTHSPL-R 77 Query: 495 TGHRILR-RSR-QRGWNRTNRKGGNPR 569 H ++R R+R QR + R+ PR Sbjct: 78 NSHAVVRARTRDQRHRSHEPRRARGPR 104 >UniRef50_Q4PDI5 Cluster: Putative uncharacterized protein; n=1; Ustilago maydis|Rep: Putative uncharacterized protein - Ustilago maydis (Smut fungus) Length = 1808 Score = 32.3 bits (70), Expect = 9.3 Identities = 19/62 (30%), Positives = 31/62 (50%), Gaps = 3/62 (4%) Frame = +3 Query: 345 QARLAIEGGTSAVAAALHRRCHQVIRKTRGEIYDSGPDSVCQ---RTHRDITRTGHRILR 515 Q +E +S +A + HR Q K+ ++ D+ V R H+D T++ HR+ R Sbjct: 898 QTSTILESLSSDLAGSAHRHAQQTSDKSSTQMLDNDEACVLAALTRHHKDRTKSPHRLKR 957 Query: 516 RS 521 RS Sbjct: 958 RS 959 >UniRef50_Q64E20 Cluster: Putative uncharacterized protein; n=1; uncultured archaeon GZfos17A3|Rep: Putative uncharacterized protein - uncultured archaeon GZfos17A3 Length = 98 Score = 32.3 bits (70), Expect = 9.3 Identities = 17/45 (37%), Positives = 23/45 (51%) Frame = +1 Query: 448 LVPIAFVNEHIETLHELDIEYCDEVAKEAGIVQIERAETPEHSSH 582 LVPI V E I+ EL+ KE ++IE + PEH S+ Sbjct: 27 LVPIIIVKEIIDQKRELERILSKHKVKEPEEIEIEEGKLPEHPSY 71 Database: uniref50 Posted date: Oct 5, 2007 11:19 AM Number of letters in database: 575,637,011 Number of sequences in database: 1,657,284 Lambda K H 0.318 0.134 0.401 Gapped Lambda K H 0.279 0.0580 0.190 Matrix: BLOSUM62 Gap Penalties: Existence: 9, Extension: 2 Number of Hits to DB: 719,245,905 Number of Sequences: 1657284 Number of extensions: 16979982 Number of successful extensions: 46649 Number of sequences better than 10.0: 127 Number of HSP's better than 10.0 without gapping: 44549 Number of HSP's successfully gapped in prelim test: 0 Number of HSP's that attempted gapping in prelim test: 0 Number of HSP's gapped (non-prelim): 46487 length of database: 575,637,011 effective HSP length: 97 effective length of database: 414,880,463 effective search space used: 43977329078 frameshift window, decay const: 40, 0.1 T: 12 A: 40 X1: 16 ( 7.3 bits) X2: 37 (14.9 bits) X3: 62 (25.0 bits) S1: 41 (21.7 bits)
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