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Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= I10A02NGRL0003_E06
         (652 letters)

Database: uniref50 
           1,657,284 sequences; 575,637,011 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

UniRef50_Q7Q0A0 Cluster: ENSANGP00000020090; n=3; Endopterygota|...   207   2e-52
UniRef50_Q17DN9 Cluster: Enhancer of split protein, putative; n=...   203   2e-51
UniRef50_Q01070 Cluster: Enhancer of split mgamma protein (E(spl...   151   1e-35
UniRef50_Q01069 Cluster: Enhancer of split mbeta protein (E(spl)...   151   1e-35
UniRef50_Q01071 Cluster: Enhancer of split mdelta protein (E(spl...   129   7e-29
UniRef50_Q9N6W7 Cluster: HLHmdelta protein; n=1; Drosophila hyde...   111   1e-23
UniRef50_Q01068 Cluster: Enhancer of split m3 protein (E(spl)m3)...   110   3e-23
UniRef50_P13098 Cluster: Enhancer of split m8 protein (E(spl)m8)...    95   1e-18
UniRef50_UPI00003BFC0E Cluster: PREDICTED: similar to deadpan CG...    89   9e-17
UniRef50_Q9NFW8 Cluster: DNA-binding-protein hairy; n=2; Enteleg...    89   1e-16
UniRef50_Q26263 Cluster: Protein deadpan; n=3; Protostomia|Rep: ...    88   2e-16
UniRef50_Q14469 Cluster: Transcription factor HES-1; n=52; Eutel...    86   6e-16
UniRef50_Q4H3N9 Cluster: Transcription factor protein; n=3; Eume...    85   1e-15
UniRef50_UPI00015B599D Cluster: PREDICTED: similar to hairy prot...    84   2e-15
UniRef50_Q90468 Cluster: HER-6 protein; n=4; Clupeocephala|Rep: ...    84   2e-15
UniRef50_UPI00003C06C0 Cluster: PREDICTED: similar to Protein ha...    83   4e-15
UniRef50_Q16NK4 Cluster: Hairy protein; n=4; Diptera|Rep: Hairy ...    81   2e-14
UniRef50_Q8T306 Cluster: Helix-loop-helix transcription factor; ...    81   3e-14
UniRef50_Q56KF1 Cluster: Enhancer of split m5 protein; n=2; Dros...    81   3e-14
UniRef50_UPI0001554A1E Cluster: PREDICTED: hypothetical protein;...    80   5e-14
UniRef50_P29303 Cluster: Protein hairy; n=2; Muscomorpha|Rep: Pr...    79   7e-14
UniRef50_Q6V6Z0 Cluster: Hairy G protein; n=1; Branchiostoma flo...    79   9e-14
UniRef50_Q208Q9 Cluster: AmphiHairyA; n=6; Branchiostoma florida...    79   9e-14
UniRef50_A7RU73 Cluster: Predicted protein; n=1; Nematostella ve...    79   1e-13
UniRef50_Q29G34 Cluster: GA19235-PA; n=1; Drosophila pseudoobscu...    78   2e-13
UniRef50_A2TIR6 Cluster: Splhairy; n=1; Panulirus argus|Rep: Spl...    78   2e-13
UniRef50_P14003 Cluster: Protein hairy; n=3; Sophophora|Rep: Pro...    77   3e-13
UniRef50_Q6V6Z2 Cluster: Hairy E protein; n=3; Branchiostoma flo...    77   5e-13
UniRef50_Q9VWX7 Cluster: CG5927-PA; n=1; Drosophila melanogaster...    75   1e-12
UniRef50_UPI0000D57461 Cluster: PREDICTED: similar to CG8704-PA;...    75   2e-12
UniRef50_Q9DEU7 Cluster: Transcription factor Her-8b; n=3; Danio...    75   2e-12
UniRef50_Q17DP5 Cluster: Hairy protein; n=2; Culicidae|Rep: Hair...    75   2e-12
UniRef50_Q9Y543 Cluster: Transcription factor HES-2; n=14; Theri...    74   3e-12
UniRef50_Q0VFM2 Cluster: Hairy and enhancer of split 6 gene 2; n...    72   1e-11
UniRef50_A7RYX4 Cluster: Predicted protein; n=2; Nematostella ve...    70   4e-11
UniRef50_Q6JJ70 Cluster: Hairy/enhancer of split; n=1; Strongylo...    70   6e-11
UniRef50_Q4H3P0 Cluster: Transcription factor protein; n=1; Cion...    70   6e-11
UniRef50_Q1ECY5 Cluster: LOC565269 protein; n=3; Danio rerio|Rep...    69   7e-11
UniRef50_UPI000065D5D5 Cluster: Transcription factor HES-3 (Hair...    67   4e-10
UniRef50_Q568C3 Cluster: Her3 protein; n=3; Danio rerio|Rep: Her...    67   4e-10
UniRef50_Q7KM13 Cluster: Hairy/enhancer-of-split related with YR...    67   4e-10
UniRef50_Q17LB7 Cluster: Transcription factor Hairy, putative; n...    66   9e-10
UniRef50_Q8T8A9 Cluster: Hairy E(SPL) like bHLH transcription fa...    64   4e-09
UniRef50_Q6P0J1 Cluster: Hairy and enhancer of split 6; n=3; Dan...    63   5e-09
UniRef50_A1L3K9 Cluster: LOC100037036 protein; n=2; Xenopus|Rep:...    63   6e-09
UniRef50_Q8AXV5 Cluster: Hairy/enhancer-of-split related with YR...    63   6e-09
UniRef50_Q5XHC4 Cluster: LOC495039 protein; n=7; Tetrapoda|Rep: ...    62   1e-08
UniRef50_Q96HZ4 Cluster: Transcription cofactor HES-6; n=18; cel...    61   2e-08
UniRef50_UPI000058443F Cluster: PREDICTED: similar to hairy E pr...    60   3e-08
UniRef50_Q5S4J7 Cluster: Enhancer of split complex m5 protein; n...    60   3e-08
UniRef50_Q0P454 Cluster: Zgc:153398; n=6; Clupeocephala|Rep: Zgc...    60   5e-08
UniRef50_Q4H3P1 Cluster: Transcription factor protein; n=1; Cion...    60   5e-08
UniRef50_UPI0000E48019 Cluster: PREDICTED: similar to hairy/enha...    60   6e-08
UniRef50_UPI00000181D8 Cluster: Homolog of Brachydanio rerio "Ha...    60   6e-08
UniRef50_UPI0000F1EAFE Cluster: PREDICTED: hypothetical protein;...    59   8e-08
UniRef50_UPI0000D5795D Cluster: PREDICTED: similar to CG11194-PA...    59   8e-08
UniRef50_UPI0000D563AB Cluster: PREDICTED: similar to CG10446-PA...    59   8e-08
UniRef50_Q6YID3 Cluster: Hairy and enhancer of split; n=1; Helob...    59   8e-08
UniRef50_Q4H3E4 Cluster: Transcription factor protein; n=1; Cion...    59   8e-08
UniRef50_Q9VJ16 Cluster: CG10446-PA; n=4; Diptera|Rep: CG10446-P...    59   1e-07
UniRef50_UPI00015B46B7 Cluster: PREDICTED: similar to GA10322-PA...    58   1e-07
UniRef50_UPI000059FC8B Cluster: PREDICTED: similar to hairy/enha...    58   2e-07
UniRef50_UPI00005846BD Cluster: PREDICTED: similar to Hey1 prote...    58   2e-07
UniRef50_Q7Q509 Cluster: ENSANGP00000020858; n=1; Anopheles gamb...    58   2e-07
UniRef50_A7RYX3 Cluster: Predicted protein; n=1; Nematostella ve...    58   2e-07
UniRef50_Q9UBP5 Cluster: Hairy/enhancer-of-split related with YR...    58   2e-07
UniRef50_A3KQ57 Cluster: Hairy and enhancer of split related-7; ...    58   2e-07
UniRef50_Q7T3J0 Cluster: Hairy and enhancer of split 5; n=3; Dan...    56   6e-07
UniRef50_Q9Y5J3 Cluster: Hairy/enhancer-of-split related with YR...    56   6e-07
UniRef50_A7S152 Cluster: Predicted protein; n=1; Nematostella ve...    56   1e-06
UniRef50_A7RYX2 Cluster: Predicted protein; n=1; Nematostella ve...    55   1e-06
UniRef50_Q8UW74 Cluster: HES-related 1A; n=4; Xenopus|Rep: HES-r...    55   2e-06
UniRef50_Q4RKD6 Cluster: Chromosome 21 SCAF15029, whole genome s...    54   2e-06
UniRef50_Q4S814 Cluster: Chromosome 9 SCAF14710, whole genome sh...    54   4e-06
UniRef50_Q4QRL6 Cluster: Hairy-related 12; n=2; Danio rerio|Rep:...    54   4e-06
UniRef50_Q6V6Y9 Cluster: Hairy H protein; n=2; Coelomata|Rep: Ha...    54   4e-06
UniRef50_UPI0000D5710A Cluster: PREDICTED: similar to CG10446-PA...    53   5e-06
UniRef50_Q9NQ87 Cluster: Hairy/enhancer-of-split related with YR...    53   7e-06
UniRef50_Q9W7B6 Cluster: BHLH-WRPW transcription factor ESR-5; n...    52   9e-06
UniRef50_Q9YI65 Cluster: Basic-helix-loop-helix transcription fa...    52   1e-05
UniRef50_UPI00015B47F2 Cluster: PREDICTED: similar to RT01017p; ...    52   2e-05
UniRef50_Q5TYJ1 Cluster: ENSANGP00000029214; n=1; Anopheles gamb...    39   2e-05
UniRef50_Q96HZ4-2 Cluster: Isoform 2 of Q96HZ4 ; n=2; Catarrhini...    51   3e-05
UniRef50_A3KQ56 Cluster: Hairy-related 1; n=3; Danio rerio|Rep: ...    51   3e-05
UniRef50_Q9BYE0 Cluster: Transcription factor HES-7; n=11; Theri...    51   3e-05
UniRef50_UPI00015A7FE8 Cluster: hairy-related 1; n=3; Euteleosto...    50   4e-05
UniRef50_Q53U32 Cluster: Enhancer of split related protein 3/7b;...    50   4e-05
UniRef50_Q2TP33 Cluster: Her5; n=1; Oryzias latipes|Rep: Her5 - ...    50   4e-05
UniRef50_Q4W593 Cluster: ESR4; n=3; Xenopus|Rep: ESR4 - Xenopus ...    50   5e-05
UniRef50_O16853 Cluster: Lin-22; n=2; Caenorhabditis|Rep: Lin-22...    50   5e-05
UniRef50_Q2TP34 Cluster: Her1-11; n=1; Oryzias latipes|Rep: Her1...    50   6e-05
UniRef50_A7SMU2 Cluster: Predicted protein; n=1; Nematostella ve...    48   1e-04
UniRef50_Q6QB00 Cluster: Her/Hey-like protein; n=2; Clupeocephal...    48   2e-04
UniRef50_Q5D212 Cluster: Hairy and enhancer of split 5; n=10; Te...    47   3e-04
UniRef50_Q4S832 Cluster: Chromosome 9 SCAF14710, whole genome sh...    47   5e-04
UniRef50_A7S155 Cluster: Predicted protein; n=1; Nematostella ve...    47   5e-04
UniRef50_Q6W4T8 Cluster: Her11; n=3; Danio rerio|Rep: Her11 - Da...    46   6e-04
UniRef50_Q504H7 Cluster: Her5 protein; n=3; Danio rerio|Rep: Her...    46   8e-04
UniRef50_Q53U31 Cluster: Enhancer of split related protein 1b; n...    46   0.001
UniRef50_Q90Z13 Cluster: Enhancer of split related 2; n=2; Xenop...    45   0.001
UniRef50_Q693N2 Cluster: Hairy; n=1; Clogmia albipunctata|Rep: H...    43   0.006
UniRef50_Q5TA89 Cluster: Transcription factor HES-5; n=11; Amnio...    43   0.006
UniRef50_UPI0000360D97 Cluster: Transcription factor HES-5 (Hair...    43   0.007
UniRef50_Q4V986 Cluster: Her4.2 protein; n=8; Danio rerio|Rep: H...    43   0.007
UniRef50_Q9PTN9 Cluster: Enhancer of split related epidermal pro...    42   0.010
UniRef50_Q28JA3 Cluster: Novel helix-loop-helix DNA binding doma...    42   0.010
UniRef50_Q1L7T5 Cluster: Her4; n=5; Percomorpha|Rep: Her4 - Oryz...    42   0.010
UniRef50_A6NFD8 Cluster: Uncharacterized protein ENSP00000343464...    36   0.015
UniRef50_Q688C9 Cluster: 213F14-1; n=9; Xenopus|Rep: 213F14-1 - ...    42   0.017
UniRef50_Q5TGS1 Cluster: Transcription factor HES-3; n=11; Euthe...    42   0.017
UniRef50_Q90464 Cluster: HER-2 protein; n=1; Danio rerio|Rep: HE...    41   0.030
UniRef50_UPI0000D9CBA5 Cluster: PREDICTED: similar to basic heli...    40   0.039
UniRef50_Q6GNE9 Cluster: LOC443665 protein; n=4; Xenopus|Rep: LO...    40   0.039
UniRef50_Q2L4U4 Cluster: BHLH protein DEC1b; n=5; Euteleostomi|R...    40   0.039
UniRef50_Q99PV5 Cluster: Class B basic helix-loop-helix protein ...    40   0.039
UniRef50_Q9C0J9 Cluster: Class B basic helix-loop-helix protein ...    40   0.039
UniRef50_O14503 Cluster: Class B basic helix-loop-helix protein ...    40   0.039
UniRef50_Q16SR7 Cluster: Class b basic helix-loop-helix protein;...    40   0.068
UniRef50_Q1L7T8 Cluster: Her7; n=1; Oryzias latipes|Rep: Her7 - ...    38   0.21 
UniRef50_Q9VGZ5 Cluster: CG17100-PA; n=4; Sophophora|Rep: CG1710...    38   0.21 
UniRef50_A7RYX5 Cluster: Predicted protein; n=1; Nematostella ve...    38   0.28 
UniRef50_P20188 Cluster: Uncharacterized 44.4 kDa protein in tra...    38   0.28 
UniRef50_Q6XLP6 Cluster: Hairy-related 9; n=2; Clupeocephala|Rep...    37   0.36 
UniRef50_Q5KHD0 Cluster: Putative uncharacterized protein; n=2; ...    37   0.36 
UniRef50_Q4SLN8 Cluster: Chromosome 15 SCAF14556, whole genome s...    37   0.48 
UniRef50_Q693M9 Cluster: Hairy; n=1; Coboldia fuscipes|Rep: Hair...    37   0.48 
UniRef50_Q2H624 Cluster: Putative uncharacterized protein; n=1; ...    36   0.64 
UniRef50_UPI0000F2B990 Cluster: PREDICTED: hypothetical protein;...    36   0.84 
UniRef50_A2AAJ9 Cluster: Obscurin; n=10; Eutheria|Rep: Obscurin ...    35   1.5  
UniRef50_Q5VST9 Cluster: Obscurin; n=50; Amniota|Rep: Obscurin -...    35   1.5  
UniRef50_UPI00005A480E Cluster: PREDICTED: similar to hairy and ...    34   2.6  
UniRef50_Q5M8T3 Cluster: HES5 protein; n=3; Eutheria|Rep: HES5 p...    34   2.6  
UniRef50_Q6CD58 Cluster: Similarity; n=1; Yarrowia lipolytica|Re...    34   2.6  
UniRef50_UPI0000DB76C3 Cluster: PREDICTED: similar to CG17100-PA...    34   3.4  
UniRef50_Q58EP4 Cluster: LOC572412 protein; n=2; Danio rerio|Rep...    34   3.4  
UniRef50_A7MB72 Cluster: MGC166429 protein; n=4; Tetrapoda|Rep: ...    34   3.4  
UniRef50_Q4S869 Cluster: Chromosome 5 SCAF14709, whole genome sh...    33   4.5  
UniRef50_A1SDB9 Cluster: Putative uncharacterized protein; n=1; ...    33   4.5  
UniRef50_Q695L3 Cluster: Obscurin-MLCK; n=5; Clupeocephala|Rep: ...    33   5.9  
UniRef50_Q92XL8 Cluster: Putative uncharacterized protein; n=1; ...    33   7.8  
UniRef50_A7RQW2 Cluster: Predicted protein; n=2; Nematostella ve...    33   7.8  

>UniRef50_Q7Q0A0 Cluster: ENSANGP00000020090; n=3;
           Endopterygota|Rep: ENSANGP00000020090 - Anopheles
           gambiae str. PEST
          Length = 210

 Score =  207 bits (505), Expect = 2e-52
 Identities = 99/125 (79%), Positives = 107/125 (85%)
 Frame = +3

Query: 81  QPVSRTYQYRKVMKPMLERKRRARINRCLDELKELMVSALQSEGENVAKLEKADILELTV 260
           +P+SRTYQYRKVMKPMLERKRRARINRCLDELKELMVSALQSEGENVAKLEKADILELTV
Sbjct: 6   EPLSRTYQYRKVMKPMLERKRRARINRCLDELKELMVSALQSEGENVAKLEKADILELTV 65

Query: 261 XXXXXXXXXXXXXXNPSVDVDRFRAGFTHAANEVSRCLASIPGVDVRLGTQLMTHLGHRL 440
                         NP +D DRFRAGFTHAANEVSRCLAS PGVD++LGT+LMTHLGHRL
Sbjct: 66  RHLHKLRRQQRLAANPVLDADRFRAGFTHAANEVSRCLASTPGVDIKLGTKLMTHLGHRL 125

Query: 441 NDMQR 455
           ND+ +
Sbjct: 126 NDLDK 130


>UniRef50_Q17DN9 Cluster: Enhancer of split protein, putative; n=3;
           Endopterygota|Rep: Enhancer of split protein, putative -
           Aedes aegypti (Yellowfever mosquito)
          Length = 229

 Score =  203 bits (496), Expect = 2e-51
 Identities = 97/125 (77%), Positives = 106/125 (84%)
 Frame = +3

Query: 81  QPVSRTYQYRKVMKPMLERKRRARINRCLDELKELMVSALQSEGENVAKLEKADILELTV 260
           +P+SRTYQYRKVMKPMLERKRRARINRCLDELKELMVSALQSEGENV+KLEKADILELTV
Sbjct: 23  EPLSRTYQYRKVMKPMLERKRRARINRCLDELKELMVSALQSEGENVSKLEKADILELTV 82

Query: 261 XXXXXXXXXXXXXXNPSVDVDRFRAGFTHAANEVSRCLASIPGVDVRLGTQLMTHLGHRL 440
                         NP +D DRFRAGFTHAANEVSRCLAS  GVD++LGT+LMTHLGHRL
Sbjct: 83  RHLHKLRRQQRLTVNPVIDADRFRAGFTHAANEVSRCLASTQGVDIKLGTKLMTHLGHRL 142

Query: 441 NDMQR 455
           ND+ +
Sbjct: 143 NDLDK 147


>UniRef50_Q01070 Cluster: Enhancer of split mgamma protein
           (E(spl)mgamma); n=13; Drosophila|Rep: Enhancer of split
           mgamma protein (E(spl)mgamma) - Drosophila melanogaster
           (Fruit fly)
          Length = 205

 Score =  151 bits (367), Expect = 1e-35
 Identities = 76/126 (60%), Positives = 92/126 (73%), Gaps = 4/126 (3%)
 Frame = +3

Query: 87  VSRTYQYRKVMKPMLERKRRARINRCLDELKELMVSALQSEGENVAKLEKADILELTV-- 260
           +S+TYQYRKVMKPMLERKRRARIN+CLDELK+LMV+ L+SEGE+V +LEKADILELTV  
Sbjct: 9   MSKTYQYRKVMKPMLERKRRARINKCLDELKDLMVATLESEGEHVTRLEKADILELTVTH 68

Query: 261 --XXXXXXXXXXXXXXNPSVDVDRFRAGFTHAANEVSRCLASIPGVDVRLGTQLMTHLGH 434
                                 + FR+G+ HA NEVSR L+ +PG++V LGTQLMTHLG 
Sbjct: 69  LQKMKQQRQHKRASGDESLTPAEGFRSGYIHAVNEVSRSLSQLPGMNVSLGTQLMTHLGQ 128

Query: 435 RLNDMQ 452
           RLN +Q
Sbjct: 129 RLNQIQ 134


>UniRef50_Q01069 Cluster: Enhancer of split mbeta protein
           (E(spl)mbeta); n=5; Drosophila|Rep: Enhancer of split
           mbeta protein (E(spl)mbeta) - Drosophila melanogaster
           (Fruit fly)
          Length = 195

 Score =  151 bits (367), Expect = 1e-35
 Identities = 79/134 (58%), Positives = 95/134 (70%), Gaps = 12/134 (8%)
 Frame = +3

Query: 87  VSRTYQYRKVMKPMLERKRRARINRCLDELKELMVSALQSEGENVAKLEKADILELTV-- 260
           +S+TYQYRKVMKPMLERKRRARIN+CLDELK++MV  L  EGE++ +LEKADILELTV  
Sbjct: 7   MSKTYQYRKVMKPMLERKRRARINKCLDELKDIMVECLTQEGEHITRLEKADILELTVEH 66

Query: 261 -----XXXXXXXXXXXXXXNPSVD-----VDRFRAGFTHAANEVSRCLASIPGVDVRLGT 410
                              +PS D      + FRAG+ HAANEVS+ LA++PGV V LGT
Sbjct: 67  MKKLRAQKQLRLSSVTGGVSPSADPKLSIAESFRAGYVHAANEVSKTLAAVPGVSVDLGT 126

Query: 411 QLMTHLGHRLNDMQ 452
           QLM+HLGHRLN +Q
Sbjct: 127 QLMSHLGHRLNYLQ 140


>UniRef50_Q01071 Cluster: Enhancer of split mdelta protein
           (E(spl)mdelta); n=4; Sophophora|Rep: Enhancer of split
           mdelta protein (E(spl)mdelta) - Drosophila melanogaster
           (Fruit fly)
          Length = 173

 Score =  129 bits (311), Expect = 7e-29
 Identities = 65/135 (48%), Positives = 91/135 (67%), Gaps = 4/135 (2%)
 Frame = +3

Query: 63  LADDGPQPVSRTYQYRKVMKPMLERKRRARINRCLDELKELMVSALQSEGENVAKLEKAD 242
           +A  G + +++T  YRKV KP+LERKRRAR+N  LDELK+L+V  + ++GE V+KLEKAD
Sbjct: 1   MAVQGQRFMTKTQHYRKVTKPLLERKRRARMNLYLDELKDLIVDTMDAQGEQVSKLEKAD 60

Query: 243 ILELTVXXXXXXXXXXXXXXN----PSVDVDRFRAGFTHAANEVSRCLASIPGVDVRLGT 410
           ILELTV                     V++D+FRAG+T AA EVS   +++PG+D++ GT
Sbjct: 61  ILELTVNYLKAQQQQRVANPQSPPPDQVNLDKFRAGYTQAAYEVSHIFSTVPGLDLKFGT 120

Query: 411 QLMTHLGHRLNDMQR 455
            LM  LGH+L DM++
Sbjct: 121 HLMKQLGHQLKDMKQ 135


>UniRef50_Q9N6W7 Cluster: HLHmdelta protein; n=1; Drosophila
           hydei|Rep: HLHmdelta protein - Drosophila hydei (Fruit
           fly)
          Length = 158

 Score =  111 bits (268), Expect = 1e-23
 Identities = 60/131 (45%), Positives = 86/131 (65%)
 Frame = +3

Query: 63  LADDGPQPVSRTYQYRKVMKPMLERKRRARINRCLDELKELMVSALQSEGENVAKLEKAD 242
           +A +G + +++T  YRKV KP+LERKRRAR+N  LDELK+L+V  + ++GE V+KLEKAD
Sbjct: 1   MAVEGQRFMTKTQHYRKVTKPLLERKRRARMNLYLDELKDLIVDTMDAQGEQVSKLEKAD 60

Query: 243 ILELTVXXXXXXXXXXXXXXNPSVDVDRFRAGFTHAANEVSRCLASIPGVDVRLGTQLMT 422
           ILELTV                 +   + +  +T AA EVS   +++PGVD++ GT LM 
Sbjct: 61  ILELTVNY---------------LKTQQQQRRYTQAAYEVSHIFSTVPGVDLKFGTHLMK 105

Query: 423 HLGHRLNDMQR 455
            LGH+L DM++
Sbjct: 106 QLGHQLKDMKQ 116


>UniRef50_Q01068 Cluster: Enhancer of split m3 protein (E(spl)m3);
           n=11; Sophophora|Rep: Enhancer of split m3 protein
           (E(spl)m3) - Drosophila melanogaster (Fruit fly)
          Length = 224

 Score =  110 bits (264), Expect = 3e-23
 Identities = 61/135 (45%), Positives = 83/135 (61%), Gaps = 13/135 (9%)
 Frame = +3

Query: 87  VSRTYQYRKVMKPMLERKRRARINRCLDELKELMVSALQSEGENVAKLEKADILELTV-- 260
           +S+TYQYRKVMKP+LERKRRARIN+CLD+LK+LMV  LQ EGE+V +LEKADILELTV  
Sbjct: 5   MSKTYQYRKVMKPLLERKRRARINKCLDDLKDLMVECLQQEGEHVTRLEKADILELTVDH 64

Query: 261 -----------XXXXXXXXXXXXXXNPSVDVDRFRAGFTHAANEVSRCLASIPGVDVRLG 407
                                      +  V+ FR+G+ HAA+++++ L      D  +G
Sbjct: 65  MRKLKQRGGLSLQGVVAGVGSPPTSTSTAHVESFRSGYVHAADQITQVLLQTQQTD-EIG 123

Query: 408 TQLMTHLGHRLNDMQ 452
            ++M  L  RL ++Q
Sbjct: 124 RKIMKFLSTRLIELQ 138


>UniRef50_P13098 Cluster: Enhancer of split m8 protein (E(spl)m8);
           n=40; Drosophila|Rep: Enhancer of split m8 protein
           (E(spl)m8) - Drosophila melanogaster (Fruit fly)
          Length = 179

 Score = 95.5 bits (227), Expect = 1e-18
 Identities = 50/123 (40%), Positives = 75/123 (60%), Gaps = 1/123 (0%)
 Frame = +3

Query: 90  SRTYQYRKVMKPMLERKRRARINRCLDELKELMVSALQSEGENVAKLEKADILELTVXXX 269
           ++T  Y+KV KPMLER+RRAR+N+CLD LK L+      +G  + +++KA++LE  V   
Sbjct: 5   TKTQIYQKVKKPMLERQRRARMNKCLDNLKTLVAELRGDDG--ILRMDKAEMLESAVIFM 62

Query: 270 XXXXXXXXXXXNP-SVDVDRFRAGFTHAANEVSRCLASIPGVDVRLGTQLMTHLGHRLND 446
                         S+ +D F+ G+ +A NEVSR +AS PG+ V LG  +MTHLG    +
Sbjct: 63  RQQKTPKKVAQEEQSLPLDSFKNGYMNAVNEVSRVMASTPGMSVDLGKSVMTHLGRVYKN 122

Query: 447 MQR 455
           +Q+
Sbjct: 123 LQQ 125


>UniRef50_UPI00003BFC0E Cluster: PREDICTED: similar to deadpan
           CG8704-PA; n=2; Apocrita|Rep: PREDICTED: similar to
           deadpan CG8704-PA - Apis mellifera
          Length = 446

 Score = 89.0 bits (211), Expect = 9e-17
 Identities = 48/128 (37%), Positives = 81/128 (63%), Gaps = 3/128 (2%)
 Frame = +3

Query: 81  QPVSRTYQYRKVMKPMLERKRRARINRCLDELKELMVSALQSEGENVAKLEKADILELTV 260
           QP     + R+  KP++E++RRARIN+CLDELK L++ A++ +    +KLEKADILE+TV
Sbjct: 13  QPGMTKAELRRSNKPIMEKRRRARINQCLDELKSLILEAMKKDPARHSKLEKADILEMTV 72

Query: 261 ---XXXXXXXXXXXXXXNPSVDVDRFRAGFTHAANEVSRCLASIPGVDVRLGTQLMTHLG 431
                            +P+V + +FR+GF+  A EVSR ++ +  VD  +  +L++HL 
Sbjct: 73  KHLQAVQRQQLSTAVATDPAV-LTKFRSGFSECATEVSRYVSHLENVDPVVKQRLVSHLN 131

Query: 432 HRLNDMQR 455
           + ++++Q+
Sbjct: 132 NCVSNLQQ 139


>UniRef50_Q9NFW8 Cluster: DNA-binding-protein hairy; n=2;
           Entelegynae|Rep: DNA-binding-protein hairy - Cupiennius
           salei (Wandering spider)
          Length = 335

 Score = 88.6 bits (210), Expect = 1e-16
 Identities = 49/124 (39%), Positives = 75/124 (60%), Gaps = 3/124 (2%)
 Frame = +3

Query: 87  VSRTYQYRKVMKPMLERKRRARINRCLDELKELMVSALQSEGENVAKLEKADILELTV-- 260
           V++  + R+  KP++E++RRARIN  L ELK L++ AL+ +    +KLEKADILE+TV  
Sbjct: 53  VTKCSETRRSTKPIMEKRRRARINNSLSELKNLILDALKKDNARHSKLEKADILEMTVKH 112

Query: 261 -XXXXXXXXXXXXXXNPSVDVDRFRAGFTHAANEVSRCLASIPGVDVRLGTQLMTHLGHR 437
                          +PS+ + +FRAGF   ANEV+R + S+ G+D  +  +L+ HL + 
Sbjct: 113 LQNLQMQQQQQQLTPDPSM-MAKFRAGFAECANEVNRFMGSMEGIDHTIRQRLLNHLANC 171

Query: 438 LNDM 449
           L  M
Sbjct: 172 LTGM 175


>UniRef50_Q26263 Cluster: Protein deadpan; n=3; Protostomia|Rep:
           Protein deadpan - Drosophila melanogaster (Fruit fly)
          Length = 435

 Score = 87.8 bits (208), Expect = 2e-16
 Identities = 48/129 (37%), Positives = 75/129 (58%), Gaps = 3/129 (2%)
 Frame = +3

Query: 78  PQPVSRTYQYRKVMKPMLERKRRARINRCLDELKELMVSALQSEGENVAKLEKADILELT 257
           P  +S+  + RK  KP++E++RRARIN CL+ELK L++ A++ +     KLEKADILE+T
Sbjct: 32  PNGLSKA-ELRKTNKPIMEKRRRARINHCLNELKSLILEAMKKDPARHTKLEKADILEMT 90

Query: 258 V---XXXXXXXXXXXXXXNPSVDVDRFRAGFTHAANEVSRCLASIPGVDVRLGTQLMTHL 428
           V                 +PSV V +F+ GF   A EV+R ++ + G+D  +  +L  HL
Sbjct: 91  VKHLQSVQRQQLNMAIQSDPSV-VQKFKTGFVECAEEVNRYVSQMDGIDTGVRQRLSAHL 149

Query: 429 GHRLNDMQR 455
               N +++
Sbjct: 150 NQCANSLEQ 158


>UniRef50_Q14469 Cluster: Transcription factor HES-1; n=52;
           Euteleostomi|Rep: Transcription factor HES-1 - Homo
           sapiens (Human)
          Length = 280

 Score = 86.2 bits (204), Expect = 6e-16
 Identities = 47/122 (38%), Positives = 73/122 (59%), Gaps = 3/122 (2%)
 Frame = +3

Query: 78  PQPVSRTYQYRKVMKPMLERKRRARINRCLDELKELMVSALQSEGENVAKLEKADILELT 257
           P       ++RK  KP++E++RRARIN  L +LK L++ AL+ +    +KLEKADILE+T
Sbjct: 25  PDKPKTASEHRKSSKPIMEKRRRARINESLSQLKTLILDALKKDSSRHSKLEKADILEMT 84

Query: 258 V---XXXXXXXXXXXXXXNPSVDVDRFRAGFTHAANEVSRCLASIPGVDVRLGTQLMTHL 428
           V                 +PSV + ++RAGF+   NEV+R L++  GV+  + T+L+ HL
Sbjct: 85  VKHLRNLQRAQMTAALSTDPSV-LGKYRAGFSECMNEVTRFLSTCEGVNTEVRTRLLGHL 143

Query: 429 GH 434
            +
Sbjct: 144 AN 145


>UniRef50_Q4H3N9 Cluster: Transcription factor protein; n=3;
           Eumetazoa|Rep: Transcription factor protein - Ciona
           intestinalis (Transparent sea squirt)
          Length = 522

 Score = 85.0 bits (201), Expect = 1e-15
 Identities = 49/131 (37%), Positives = 79/131 (60%), Gaps = 4/131 (3%)
 Frame = +3

Query: 75  GPQPVSRTY-QYRKVMKPMLERKRRARINRCLDELKELMVSALQSEGENVAKLEKADILE 251
           G   +  TY + +K  KP++E++RRARIN  L+ELK +++ AL+ +    +KLEKADILE
Sbjct: 19  GDVDLGGTYIERQKSSKPIMEKRRRARINSSLNELKSILLEALKKDSTRHSKLEKADILE 78

Query: 252 LTVXXXXXXXXXXXXXXNPSVD---VDRFRAGFTHAANEVSRCLASIPGVDVRLGTQLMT 422
           +TV              + S+D   +++++AGF    NEV R L++  GV V + T+L+ 
Sbjct: 79  MTV-KYLKNVERQRLSVSLSIDPAEINQYKAGFNECRNEVMRFLSTCEGVTVDVRTRLLN 137

Query: 423 HLGHRLNDMQR 455
           HL   L+ +Q+
Sbjct: 138 HLATCLHSIQK 148


>UniRef50_UPI00015B599D Cluster: PREDICTED: similar to hairy
           protein; n=1; Nasonia vitripennis|Rep: PREDICTED:
           similar to hairy protein - Nasonia vitripennis
          Length = 376

 Score = 84.2 bits (199), Expect = 2e-15
 Identities = 48/126 (38%), Positives = 76/126 (60%), Gaps = 3/126 (2%)
 Frame = +3

Query: 78  PQPVSRTYQYRKVMKPMLERKRRARINRCLDELKELMVSALQSEGENVAKLEKADILELT 257
           P    R+ + R+  KP++E++RRARIN CL++LK L++ A++ +    +KLEKADILE+T
Sbjct: 47  PAAPRRSSENRRSNKPIMEKRRRARINNCLNDLKALILDAMKKDPARHSKLEKADILEMT 106

Query: 258 V---XXXXXXXXXXXXXXNPSVDVDRFRAGFTHAANEVSRCLASIPGVDVRLGTQLMTHL 428
           V                 +P+V +++FRAGFT  ANEV R     PG++  +  +L+ HL
Sbjct: 107 VKHLETLQRQQVALASATDPNV-LNKFRAGFTECANEVGR----FPGLEASMKRRLLAHL 161

Query: 429 GHRLND 446
              L++
Sbjct: 162 STCLSN 167


>UniRef50_Q90468 Cluster: HER-6 protein; n=4; Clupeocephala|Rep:
           HER-6 protein - Danio rerio (Zebrafish) (Brachydanio
           rerio)
          Length = 334

 Score = 84.2 bits (199), Expect = 2e-15
 Identities = 46/120 (38%), Positives = 72/120 (60%), Gaps = 3/120 (2%)
 Frame = +3

Query: 78  PQPVSRTYQYRKVMKPMLERKRRARINRCLDELKELMVSALQSEGENVAKLEKADILELT 257
           P       ++RK  KP++E++RRARIN  L +LK L++ AL+ +    +KLEKADILE+T
Sbjct: 89  PDKPKTASEHRKSSKPIMEKRRRARINESLGQLKTLILDALKKDSSRHSKLEKADILEMT 148

Query: 258 V---XXXXXXXXXXXXXXNPSVDVDRFRAGFTHAANEVSRCLASIPGVDVRLGTQLMTHL 428
           V                 +P+V + ++RAGF+   NEV+R L++  GV+  + T+L+ HL
Sbjct: 149 VKHLRNMQRAQMTAALNTDPTV-LGKYRAGFSECMNEVTRFLSTCEGVNTEVRTRLLGHL 207


>UniRef50_UPI00003C06C0 Cluster: PREDICTED: similar to Protein
           hairy; n=1; Apis mellifera|Rep: PREDICTED: similar to
           Protein hairy - Apis mellifera
          Length = 363

 Score = 83.4 bits (197), Expect = 4e-15
 Identities = 48/123 (39%), Positives = 74/123 (60%), Gaps = 3/123 (2%)
 Frame = +3

Query: 93  RTYQYRKVMKPMLERKRRARINRCLDELKELMVSALQSEGENVAKLEKADILELTV---X 263
           R+ + R+  KP++E++RRARIN CL++LK L++ A++ +    +KLEKADILE+TV    
Sbjct: 45  RSGENRRSNKPIMEKRRRARINNCLNDLKTLILDAMKKDPARHSKLEKADILEMTVKHLE 104

Query: 264 XXXXXXXXXXXXXNPSVDVDRFRAGFTHAANEVSRCLASIPGVDVRLGTQLMTHLGHRLN 443
                        +P+V +++FRAGFT  A EV R     PG+D  +  +LM HL   L 
Sbjct: 105 TLQRQQVALAAATDPNV-LNKFRAGFTECAGEVGR----FPGLDASVKRRLMAHLASCLG 159

Query: 444 DMQ 452
            ++
Sbjct: 160 PVE 162


>UniRef50_Q16NK4 Cluster: Hairy protein; n=4; Diptera|Rep: Hairy
           protein - Aedes aegypti (Yellowfever mosquito)
          Length = 343

 Score = 81.0 bits (191), Expect = 2e-14
 Identities = 49/128 (38%), Positives = 75/128 (58%), Gaps = 4/128 (3%)
 Frame = +3

Query: 81  QPV-SRTYQYRKVMKPMLERKRRARINRCLDELKELMVSALQSEGENVAKLEKADILELT 257
           QPV  R    R+  KP++E++RRARIN CL+ELK L++ A++ +    +KLEKADILE+T
Sbjct: 26  QPVVKRPSDNRRSNKPIMEKRRRARINNCLNELKTLILDAMKKDPARHSKLEKADILEMT 85

Query: 258 V---XXXXXXXXXXXXXXNPSVDVDRFRAGFTHAANEVSRCLASIPGVDVRLGTQLMTHL 428
           V                 +P+V +++F+AGF   A EVSR     P +D     +L+ HL
Sbjct: 86  VKHLENLQRQQNAMSQATDPNV-MNKFKAGFNECAQEVSR----FPDIDPMTRRRLLAHL 140

Query: 429 GHRLNDMQ 452
            + +N ++
Sbjct: 141 SNCINGVK 148


>UniRef50_Q8T306 Cluster: Helix-loop-helix transcription factor;
           n=2; Tribolium castaneum|Rep: Helix-loop-helix
           transcription factor - Tribolium castaneum (Red flour
           beetle)
          Length = 249

 Score = 80.6 bits (190), Expect = 3e-14
 Identities = 50/124 (40%), Positives = 72/124 (58%), Gaps = 3/124 (2%)
 Frame = +3

Query: 93  RTYQYRKVMKPMLERKRRARINRCLDELKELMVSALQSEGENVAKLEKADILELTV---X 263
           R    R+  KP++E++RRARIN  L+ELK L++ A++ +    +KLEKADILE+TV    
Sbjct: 30  RVSDNRRSNKPIMEKRRRARINNSLNELKTLILDAMKKDPARHSKLEKADILEMTVKHLQ 89

Query: 264 XXXXXXXXXXXXXNPSVDVDRFRAGFTHAANEVSRCLASIPGVDVRLGTQLMTHLGHRLN 443
                        +PSV V +FRAGF+  A+EV R     PG+D  +  +L+ HL   LN
Sbjct: 90  NLQRQQAAMSAATDPSV-VSKFRAGFSECASEVGR----FPGLDPVVKRRLLQHLASCLN 144

Query: 444 DMQR 455
             Q+
Sbjct: 145 QGQK 148


>UniRef50_Q56KF1 Cluster: Enhancer of split m5 protein; n=2;
           Drosophila melanogaster|Rep: Enhancer of split m5
           protein - Drosophila melanogaster (Fruit fly)
          Length = 129

 Score = 80.6 bits (190), Expect = 3e-14
 Identities = 58/115 (50%), Positives = 81/115 (70%)
 Frame = +3

Query: 87  VSRTYQYRKVMKPMLERKRRARINRCLDELKELMVSALQSEGENVAKLEKADILELTVXX 266
           VS+T  Y KV KP+LER+RRAR+N+CLD LK L V+  Q + + + +++KA++LE     
Sbjct: 11  VSKTQHYLKVKKPLLERQRRARMNKCLDTLKTL-VAEFQGD-DAILRMDKAEMLE-AAXX 67

Query: 267 XXXXXXXXXXXXNPSVDVDRFRAGFTHAANEVSRCLASIPGVDVRLGTQLMTHLG 431
                             D F+ G+ +A +E+SR +A  P + V +G  +MTHLG
Sbjct: 68  XXXXXXXXXXXXXXXXXXDSFKNGYMNAVSEISRVMACTPAMSVDVGKTVMTHLG 122


>UniRef50_UPI0001554A1E Cluster: PREDICTED: hypothetical protein;
           n=1; Ornithorhynchus anatinus|Rep: PREDICTED:
           hypothetical protein - Ornithorhynchus anatinus
          Length = 287

 Score = 79.8 bits (188), Expect = 5e-14
 Identities = 43/106 (40%), Positives = 67/106 (63%), Gaps = 3/106 (2%)
 Frame = +3

Query: 120 KPMLERKRRARINRCLDELKELMVSALQSEGENVAKLEKADILELTV---XXXXXXXXXX 290
           KP++E++RRARIN  L +LK L++ AL+ +    +KLEKADILE+TV             
Sbjct: 21  KPIMEKRRRARINESLSQLKTLILDALKKDSSRHSKLEKADILEMTVKHLRNLQRAQMTA 80

Query: 291 XXXXNPSVDVDRFRAGFTHAANEVSRCLASIPGVDVRLGTQLMTHL 428
               +P+V + ++RAGF+   NEV+R L++  GV+  + T+L+ HL
Sbjct: 81  ALSSDPTV-LGKYRAGFSECMNEVTRFLSTCEGVNTEVRTRLLGHL 125


>UniRef50_P29303 Cluster: Protein hairy; n=2; Muscomorpha|Rep:
           Protein hairy - Drosophila virilis (Fruit fly)
          Length = 378

 Score = 79.4 bits (187), Expect = 7e-14
 Identities = 46/118 (38%), Positives = 70/118 (59%), Gaps = 3/118 (2%)
 Frame = +3

Query: 108 RKVMKPMLERKRRARINRCLDELKELMVSALQSEGENVAKLEKADILELTV---XXXXXX 278
           R+  KP++E++RRARIN CL+ELK L++ A + +    +KLEKADILE TV         
Sbjct: 38  RRSNKPIMEKRRRARINNCLNELKTLILDATKKDPARHSKLEKADILEKTVKHLQELQRQ 97

Query: 279 XXXXXXXXNPSVDVDRFRAGFTHAANEVSRCLASIPGVDVRLGTQLMTHLGHRLNDMQ 452
                   +P + +++F+AGF   ANEVSR     PG+D     +L+ HL + +N ++
Sbjct: 98  QAAMQQAADPKI-INKFKAGFADCANEVSR----FPGLDSTQRRRLLQHLSNCINGVK 150


>UniRef50_Q6V6Z0 Cluster: Hairy G protein; n=1; Branchiostoma
           floridae|Rep: Hairy G protein - Branchiostoma floridae
           (Florida lancelet) (Amphioxus)
          Length = 267

 Score = 79.0 bits (186), Expect = 9e-14
 Identities = 41/112 (36%), Positives = 66/112 (58%), Gaps = 2/112 (1%)
 Frame = +3

Query: 99  YQYRKVMKPMLERKRRARINRCLDELKELMVSALQSEGENVAKLEKADILELTV--XXXX 272
           YQ RK  KP++E++RRARIN  L+ELK L++   +++  + +KLEKADILE+ V      
Sbjct: 13  YQSRKSSKPLMEKRRRARINSSLNELKNLILDTYKNDSTHHSKLEKADILEIAVKHVRSL 72

Query: 273 XXXXXXXXXXNPSVDVDRFRAGFTHAANEVSRCLASIPGVDVRLGTQLMTHL 428
                          + R+RAG++    EV+R + ++ GVD ++  +L+ HL
Sbjct: 73  QRQQMAAAVSTDPAALGRYRAGYSRCRAEVARFMGTVDGVDPQVRQKLLNHL 124


>UniRef50_Q208Q9 Cluster: AmphiHairyA; n=6; Branchiostoma
           floridae|Rep: AmphiHairyA - Branchiostoma floridae
           (Florida lancelet) (Amphioxus)
          Length = 300

 Score = 79.0 bits (186), Expect = 9e-14
 Identities = 44/111 (39%), Positives = 65/111 (58%), Gaps = 2/111 (1%)
 Frame = +3

Query: 102 QYRKVMKPMLERKRRARINRCLDELKELMVSALQSEGENVAKLEKADILELTV--XXXXX 275
           Q RK  KP++E++RRARIN  L++LK L++ AL+ +    +KLEKADILE+TV       
Sbjct: 19  QRRKSSKPIMEKRRRARINDSLNQLKTLILDALKKDSSRHSKLEKADILEMTVKHLRNLQ 78

Query: 276 XXXXXXXXXNPSVDVDRFRAGFTHAANEVSRCLASIPGVDVRLGTQLMTHL 428
                       V + ++RAG++    EVSR L    GVD ++  +L+ HL
Sbjct: 79  RQQIADAVIRDPVALSKYRAGYSECMTEVSRFLTGSDGVDGQVQQRLLGHL 129


>UniRef50_A7RU73 Cluster: Predicted protein; n=1; Nematostella
           vectensis|Rep: Predicted protein - Nematostella
           vectensis
          Length = 254

 Score = 78.6 bits (185), Expect = 1e-13
 Identities = 45/111 (40%), Positives = 69/111 (62%), Gaps = 4/111 (3%)
 Frame = +3

Query: 108 RKVMKPMLERKRRARINRCLDELKELMVSALQSEGENVAKLEKADILELTV----XXXXX 275
           RK  KPM+E++RRARIN+ L+ELK L++ A++ +    +KLEKADILE+TV         
Sbjct: 18  RKSSKPMMEKRRRARINQSLNELKILILEAMKKDTSCYSKLEKADILEMTVKYLRAMKTT 77

Query: 276 XXXXXXXXXNPSVDVDRFRAGFTHAANEVSRCLASIPGVDVRLGTQLMTHL 428
                    +PS  V ++RAGF   A EV+R   +   VD+++ T++++HL
Sbjct: 78  QQLTGIVPSDPS-SVAQYRAGFNECALEVTRYFMANDNVDLQMKTRILSHL 127


>UniRef50_Q29G34 Cluster: GA19235-PA; n=1; Drosophila
           pseudoobscura|Rep: GA19235-PA - Drosophila pseudoobscura
           (Fruit fly)
          Length = 217

 Score = 77.8 bits (183), Expect = 2e-13
 Identities = 38/60 (63%), Positives = 45/60 (75%)
 Frame = +3

Query: 81  QPVSRTYQYRKVMKPMLERKRRARINRCLDELKELMVSALQSEGENVAKLEKADILELTV 260
           Q +SR+ +YRKVMKP+LERKRRARIN CLDELK ++      E   + KLEKADILEL V
Sbjct: 81  QGLSRSSEYRKVMKPLLERKRRARINNCLDELKIIIADLAHMETTGLNKLEKADILELAV 140


>UniRef50_A2TIR6 Cluster: Splhairy; n=1; Panulirus argus|Rep:
           Splhairy - Panulirus argus (Spiny lobster)
          Length = 253

 Score = 77.8 bits (183), Expect = 2e-13
 Identities = 44/109 (40%), Positives = 60/109 (55%), Gaps = 2/109 (1%)
 Frame = +3

Query: 108 RKVMKPMLERKRRARINRCLDELKELMVSALQSEGENVAKLEKADILELTV-XXXXXXXX 284
           R+  KP++E+KRR RIN CL++LK L++  L+ +     KLEKADILE+TV         
Sbjct: 20  RRTNKPIMEKKRRQRINDCLNQLKNLVLEGLKKDPSRYNKLEKADILEMTVRHVQALHRH 79

Query: 285 XXXXXXNPSVD-VDRFRAGFTHAANEVSRCLASIPGVDVRLGTQLMTHL 428
                  P VD   +FRAGF H A EV R L     V     ++++ HL
Sbjct: 80  ESALSRQPPVDAAAKFRAGFAHCAAEVGRFLEGDTSVSAGQRSRILLHL 128


>UniRef50_P14003 Cluster: Protein hairy; n=3; Sophophora|Rep:
           Protein hairy - Drosophila melanogaster (Fruit fly)
          Length = 337

 Score = 77.4 bits (182), Expect = 3e-13
 Identities = 45/118 (38%), Positives = 69/118 (58%), Gaps = 3/118 (2%)
 Frame = +3

Query: 108 RKVMKPMLERKRRARINRCLDELKELMVSALQSEGENVAKLEKADILELTV---XXXXXX 278
           R+  KP++E++RRARIN CL+ELK L++ A + +    +KLEKADILE TV         
Sbjct: 32  RRSNKPIMEKRRRARINNCLNELKTLILDATKKDPARHSKLEKADILEKTVKHLQELQRQ 91

Query: 279 XXXXXXXXNPSVDVDRFRAGFTHAANEVSRCLASIPGVDVRLGTQLMTHLGHRLNDMQ 452
                   +P + V++F+AGF    NEVSR     PG++     +L+ HL + +N ++
Sbjct: 92  QAAMQQAADPKI-VNKFKAGFADCVNEVSR----FPGIEPAQRRRLLQHLSNCINGVK 144


>UniRef50_Q6V6Z2 Cluster: Hairy E protein; n=3; Branchiostoma
           floridae|Rep: Hairy E protein - Branchiostoma floridae
           (Florida lancelet) (Amphioxus)
          Length = 345

 Score = 76.6 bits (180), Expect = 5e-13
 Identities = 46/119 (38%), Positives = 68/119 (57%), Gaps = 3/119 (2%)
 Frame = +3

Query: 81  QPVSRTYQYRKVMKPMLERKRRARINRCLDELKELMVSALQSEGENVAKLEKADILELTV 260
           Q  SR  + RK  KP++E++RRARIN  L++LK L++ AL+ +    +KLEKADILE+TV
Sbjct: 4   QKDSRPSEGRKSSKPIMEKRRRARINDSLNQLKTLILDALKKDSSRHSKLEKADILEMTV 63

Query: 261 ---XXXXXXXXXXXXXXNPSVDVDRFRAGFTHAANEVSRCLASIPGVDVRLGTQLMTHL 428
                            +P+V + ++RAGF     EVS  L S   V+  +  +L+ HL
Sbjct: 64  KHLRNLQRQHVAAAVSTDPNV-LGQYRAGFNECMTEVSSFLGSASTVETEVHQRLLNHL 121


>UniRef50_Q9VWX7 Cluster: CG5927-PA; n=1; Drosophila
           melanogaster|Rep: CG5927-PA - Drosophila melanogaster
           (Fruit fly)
          Length = 149

 Score = 74.9 bits (176), Expect = 1e-12
 Identities = 32/57 (56%), Positives = 45/57 (78%)
 Frame = +3

Query: 90  SRTYQYRKVMKPMLERKRRARINRCLDELKELMVSALQSEGENVAKLEKADILELTV 260
           SR++QYR+V KPM+ERKRR+RINRCLD +K+L+      +GE +AK++  D+LEL V
Sbjct: 16  SRSHQYREVFKPMMERKRRSRINRCLDFIKDLLQEVSHLDGETMAKMDMGDVLELAV 72


>UniRef50_UPI0000D57461 Cluster: PREDICTED: similar to CG8704-PA;
           n=1; Tribolium castaneum|Rep: PREDICTED: similar to
           CG8704-PA - Tribolium castaneum
          Length = 371

 Score = 74.5 bits (175), Expect = 2e-12
 Identities = 44/117 (37%), Positives = 67/117 (57%), Gaps = 3/117 (2%)
 Frame = +3

Query: 102 QYRKVMKPMLERKRRARINRCLDELKELMVSALQSEGENVAKLEKADILELTV---XXXX 272
           + RK  KP++E++RRARIN CL+E+K L++ A+  +    +KLEKADILE+ V       
Sbjct: 23  ELRKTHKPIMEKRRRARINHCLNEIKTLILEAMNKDPARHSKLEKADILEMAVKHLQNVQ 82

Query: 273 XXXXXXXXXXNPSVDVDRFRAGFTHAANEVSRCLASIPGVDVRLGTQLMTHLGHRLN 443
                     +PSV + +F++GF   ANE+ R   S   VD  L  ++ +HL   +N
Sbjct: 83  RQQLAVAMASDPSV-LRKFKSGFNECANEIDR-FVSQSEVDDGLKDRMRSHLQKCIN 137


>UniRef50_Q9DEU7 Cluster: Transcription factor Her-8b; n=3; Danio
           rerio|Rep: Transcription factor Her-8b - Danio rerio
           (Zebrafish) (Brachydanio rerio)
          Length = 221

 Score = 74.5 bits (175), Expect = 2e-12
 Identities = 44/124 (35%), Positives = 66/124 (53%), Gaps = 5/124 (4%)
 Frame = +3

Query: 72  DGPQPVSRTYQYRKVMKPMLERKRRARINRCLDELKELMVSALQSEGENVAKLEKADILE 251
           +GP+      + RK+ KP++E+KRR RIN  L++LK +MV A   +    +KLEKAD+LE
Sbjct: 8   NGPEKNFNAKEERKLRKPLIEKKRRERINSSLEQLKGIMVDAYNLD---QSKLEKADVLE 64

Query: 252 LTVXXXXXXXXXXXXXXNPSVDV-----DRFRAGFTHAANEVSRCLASIPGVDVRLGTQL 416
           +TV              + S         R+ +G+    +EV   L S PG+D  LG +L
Sbjct: 65  ITVQHMENLQRGHGQGGSNSPGTGFESRQRYSSGYIQCMHEVHNLLLSCPGMDKTLGARL 124

Query: 417 MTHL 428
           + HL
Sbjct: 125 LNHL 128


>UniRef50_Q17DP5 Cluster: Hairy protein; n=2; Culicidae|Rep: Hairy
           protein - Aedes aegypti (Yellowfever mosquito)
          Length = 343

 Score = 74.5 bits (175), Expect = 2e-12
 Identities = 41/112 (36%), Positives = 66/112 (58%), Gaps = 3/112 (2%)
 Frame = +3

Query: 102 QYRKVMKPMLERKRRARINRCLDELKELMVSALQSEGENVAKLEKADILELTV---XXXX 272
           + RK  KP++E+KRRARIN  L++LK L++ A++ +    +KLEKADIL+LTV       
Sbjct: 27  EIRKTNKPIMEKKRRARINNYLNDLKALLLDAMKKDPIRHSKLEKADILDLTVKHLQDLE 86

Query: 273 XXXXXXXXXXNPSVDVDRFRAGFTHAANEVSRCLASIPGVDVRLGTQLMTHL 428
                     +P+V VD+F++GF     E+ + L ++  VD  +  ++  HL
Sbjct: 87  RRKLAIAMAVDPTV-VDKFKSGFNECIEEIDKYLNTVSSVDGGMKQRISNHL 137


>UniRef50_Q9Y543 Cluster: Transcription factor HES-2; n=14;
           Theria|Rep: Transcription factor HES-2 - Homo sapiens
           (Human)
          Length = 173

 Score = 73.7 bits (173), Expect = 3e-12
 Identities = 40/120 (33%), Positives = 65/120 (54%)
 Frame = +3

Query: 78  PQPVSRTYQYRKVMKPMLERKRRARINRCLDELKELMVSALQSEGENVAKLEKADILELT 257
           P+      + RK +KP+LE++RRARIN+ L +LK L++  L  E  N +KLEKAD+LE+T
Sbjct: 4   PRRAGDAAELRKSLKPLLEKRRRARINQSLSQLKGLILPLLGRENSNCSKLEKADVLEMT 63

Query: 258 VXXXXXXXXXXXXXXNPSVDVDRFRAGFTHAANEVSRCLASIPGVDVRLGTQLMTHLGHR 437
           V               P +  D +R G++     ++R L +   ++  +  +L+ HL  R
Sbjct: 64  VRFLQELPASSWPTAAP-LPCDSYREGYSACVARLARVLPACRVLEPAVSARLLEHLWRR 122


>UniRef50_Q0VFM2 Cluster: Hairy and enhancer of split 6 gene 2; n=6;
           Coelomata|Rep: Hairy and enhancer of split 6 gene 2 -
           Xenopus tropicalis (Western clawed frog) (Silurana
           tropicalis)
          Length = 189

 Score = 71.7 bits (168), Expect = 1e-11
 Identities = 42/110 (38%), Positives = 59/110 (53%), Gaps = 3/110 (2%)
 Frame = +3

Query: 108 RKVMKPMLERKRRARINRCLDELKELMVSALQSEGENVAKLEKADILELTVXXXXXXXXX 287
           RK+ KP++ERKRR RIN CL++LKE ++ A   +    +KLEKADILE+TV         
Sbjct: 18  RKLRKPLIERKRRERINTCLEQLKETVIKAFHLD---QSKLEKADILEMTVRHLQNIQKS 74

Query: 288 XXXXXNPSVDVD---RFRAGFTHAANEVSRCLASIPGVDVRLGTQLMTHL 428
                     VD   RF  G+    +E+   L +   +D  LG +L+ HL
Sbjct: 75  KSTGEPSQGSVDAQQRFSTGYIQCMHELHSLLLTCDWMDPALGARLLNHL 124


>UniRef50_A7RYX4 Cluster: Predicted protein; n=2; Nematostella
           vectensis|Rep: Predicted protein - Nematostella
           vectensis
          Length = 213

 Score = 70.1 bits (164), Expect = 4e-11
 Identities = 43/107 (40%), Positives = 56/107 (52%)
 Frame = +3

Query: 108 RKVMKPMLERKRRARINRCLDELKELMVSALQSEGENVAKLEKADILELTVXXXXXXXXX 287
           RK  KPM+E+ RRARIN  L+ELK L++  L  +    +K+EKADILE+TV         
Sbjct: 20  RKAKKPMMEKLRRARINDSLNELKVLVLELLNKDASRYSKMEKADILEMTVGYLRAAQRI 79

Query: 288 XXXXXNPSVDVDRFRAGFTHAANEVSRCLASIPGVDVRLGTQLMTHL 428
                  +   D FRAGF   A EVS  L+        L   L++HL
Sbjct: 80  EKRTQGSTPPSD-FRAGFNACAVEVSNRLSPADANTDNLRETLLSHL 125


>UniRef50_Q6JJ70 Cluster: Hairy/enhancer of split; n=1;
           Strongylocentrotus purpuratus|Rep: Hairy/enhancer of
           split - Strongylocentrotus purpuratus (Purple sea
           urchin)
          Length = 400

 Score = 69.7 bits (163), Expect = 6e-11
 Identities = 48/138 (34%), Positives = 72/138 (52%), Gaps = 6/138 (4%)
 Frame = +3

Query: 48  EIAYSLADDGPQPVSRTYQYRKVMKPMLERKRRARINRCLDELKELMVSALQSEGENVAK 227
           E+ +S      +P       RK  KP +E++RRARIN  L +LK L++ A   +    +K
Sbjct: 5   EVYFSKMPVDTKPKIHEGSGRKSSKPQMEKRRRARINDSLGQLKALILEATNKDSSRHSK 64

Query: 228 LEKADILELTV---XXXXXXXXXXXXXXNPSVDVDRFRAGFTHAANEVSRC---LASIPG 389
           LEKADILE+TV                 +P++ V RFR G++   +EV+R    + +I G
Sbjct: 65  LEKADILEMTVKHLRNIQRNQLTGPLSSDPNM-VSRFRQGYSECVHEVARFFTNIENIGG 123

Query: 390 VDVRLGTQLMTHLGHRLN 443
            D+RL   L+ HL +  N
Sbjct: 124 PDMRL--SLINHLANTCN 139


>UniRef50_Q4H3P0 Cluster: Transcription factor protein; n=1; Ciona
           intestinalis|Rep: Transcription factor protein - Ciona
           intestinalis (Transparent sea squirt)
          Length = 333

 Score = 69.7 bits (163), Expect = 6e-11
 Identities = 44/116 (37%), Positives = 67/116 (57%), Gaps = 5/116 (4%)
 Frame = +3

Query: 108 RKVMKPMLERKRRARINRCLDELKELMVSALQSEGENV-AKLEKADILELTV---XXXXX 275
           R+  KP++E++RR RIN+ L+ELK +++ AL+ +     +KLEKADILE+TV        
Sbjct: 25  RRASKPLMEKRRRERINKSLNELKSILLHALRKDQSTCHSKLEKADILEMTVRYLRGIQR 84

Query: 276 XXXXXXXXXNPSVDVDRFRAGFTHAANEVSRCLA-SIPGVDVRLGTQLMTHLGHRL 440
                    +PSV V ++R G+    NEVS  L  S   V   + ++L+ HLG+ L
Sbjct: 85  QRMNAAITLDPSV-VSKYRNGYVECKNEVSHFLENSSENVHPDVKSRLINHLGNTL 139


>UniRef50_Q1ECY5 Cluster: LOC565269 protein; n=3; Danio rerio|Rep:
           LOC565269 protein - Danio rerio (Zebrafish) (Brachydanio
           rerio)
          Length = 223

 Score = 69.3 bits (162), Expect = 7e-11
 Identities = 41/108 (37%), Positives = 57/108 (52%), Gaps = 1/108 (0%)
 Frame = +3

Query: 108 RKVMKPMLERKRRARINRCLDELKELMVSALQSEGENVAKLEKADILELTVXXXXXXXXX 287
           RK+ KP++ERKRR RIN CLD+L+E +V   + +    +KLEKADILE+TV         
Sbjct: 35  RKLRKPLIERKRRERINLCLDQLRETVVGVFKPD---QSKLEKADILEMTVKHLQNIQSS 91

Query: 288 XXXXXNPSVDV-DRFRAGFTHAANEVSRCLASIPGVDVRLGTQLMTHL 428
                  +     R+  G+     EV   L S   +D  LG++L  HL
Sbjct: 92  RVSDPVLNTGARQRYSTGYIQCMQEVHNLLHSCDWMDKTLGSRLFNHL 139


>UniRef50_UPI000065D5D5 Cluster: Transcription factor HES-3 (Hairy
           and enhancer of split 3).; n=1; Takifugu rubripes|Rep:
           Transcription factor HES-3 (Hairy and enhancer of split
           3). - Takifugu rubripes
          Length = 271

 Score = 66.9 bits (156), Expect = 4e-10
 Identities = 48/129 (37%), Positives = 70/129 (54%), Gaps = 3/129 (2%)
 Frame = +3

Query: 51  IAYSLADDGPQPVSRTYQYRKVMKPMLERKRRARINRCLDELKELMVSALQSEGENVAKL 230
           +A + ++D P+ VS     +KV KP++E+KRRARIN+CLD+LK +++ +  S      KL
Sbjct: 2   VATTDSEDPPKHVSG----KKVSKPLMEKKRRARINKCLDQLK-ILLESYYSTSIRKRKL 56

Query: 231 EKADILELTVXXXXXXXXXXXXXXNPSVDVDRFRAGFTHAANEVSRCLA---SIPGVDVR 401
           EKADILELTV                S   D  ++GF   A  V + L    S+ G+D  
Sbjct: 57  EKADILELTVNHLRNLQKHQSCNIASSESSDH-QSGFRRCAANVDQFLLMADSVNGIDRW 115

Query: 402 LGTQLMTHL 428
           + +QL   L
Sbjct: 116 MLSQLSAKL 124


>UniRef50_Q568C3 Cluster: Her3 protein; n=3; Danio rerio|Rep: Her3
           protein - Danio rerio (Zebrafish) (Brachydanio rerio)
          Length = 253

 Score = 66.9 bits (156), Expect = 4e-10
 Identities = 57/145 (39%), Positives = 75/145 (51%), Gaps = 3/145 (2%)
 Frame = +3

Query: 9   YTFTEHTMSTMSYEIAYSLADDGPQPVSRTYQYRKVMKPMLERKRRARINRCLDELKELM 188
           +  TEH + TM+   + S A   PQ V      +KV KP++E+KRRARIN+CL++LK L+
Sbjct: 16  FKHTEH-LRTMA-AASNSAATAKPQNV------KKVSKPLMEKKRRARINKCLNQLKSLL 67

Query: 189 VSALQSEGENVAKLEKADILELTVXXXXXXXXXXXXXXNPSVDVDRFRAGFTHAANEVSR 368
            SA  S      KLEKADILELTV              + + D   + AG+    N VS 
Sbjct: 68  ESAC-SNNIRKRKLEKADILELTV-KHLRHLQNTKRGLSKACDSAEYHAGYRSCLNTVSH 125

Query: 369 CL-ASIPGVDVR--LGTQLMTHLGH 434
            L AS    D R  + T L + L H
Sbjct: 126 YLRASDTDRDSRSIMLTNLTSGLNH 150


>UniRef50_Q7KM13 Cluster: Hairy/enhancer-of-split related with YRPW
           motif protein; n=2; Sophophora|Rep:
           Hairy/enhancer-of-split related with YRPW motif protein
           - Drosophila melanogaster (Fruit fly)
          Length = 425

 Score = 66.9 bits (156), Expect = 4e-10
 Identities = 47/121 (38%), Positives = 66/121 (54%), Gaps = 5/121 (4%)
 Frame = +3

Query: 81  QPVSRTYQYRKVMKPMLERKRRARINRCLDELKELMVSALQSEGENVAKLEKADILELTV 260
           +P S     RK  + ++E+KRR RIN  L ELK L+ SA + +G   AKLEKA+IL+LTV
Sbjct: 92  EPGSCQLMSRKKRRGVIEKKRRDRINSSLTELKRLVPSAYEKQGS--AKLEKAEILQLTV 149

Query: 261 XXXXXXXXXXXXXXN---PSVDVDRFRAGFTHAANEVSRCLASIPGVDVR--LGTQLMTH 425
                         +     V +D    GF   A EV+R L +I G+D++  L  +LM+H
Sbjct: 150 EHLKSLQSKTLDSLSYDPQRVAMDYHIIGFRECAAEVARYLVTIEGMDIQDPLRLRLMSH 209

Query: 426 L 428
           L
Sbjct: 210 L 210


>UniRef50_Q17LB7 Cluster: Transcription factor Hairy, putative; n=2;
           Culicidae|Rep: Transcription factor Hairy, putative -
           Aedes aegypti (Yellowfever mosquito)
          Length = 298

 Score = 65.7 bits (153), Expect = 9e-10
 Identities = 48/114 (42%), Positives = 63/114 (55%), Gaps = 7/114 (6%)
 Frame = +3

Query: 108 RKVMKPMLERKRRARINRCLDELKELMVSALQSEGENVAKLEKADILELTVXXXXXXXXX 287
           RK  + ++E+KRR RIN  L ELK L+ SA + +G   AKLEKA+IL+LTV         
Sbjct: 20  RKRRRGVIEKKRRDRINSSLSELKRLVPSAYEKQGS--AKLEKAEILQLTV--DHLKQLH 75

Query: 288 XXXXXNPSVDVDRFR-----AGFTHAANEVSRCLASIPGVDVR--LGTQLMTHL 428
                + S D  RF       GF     EV+R L SI G+DV+  L  +LM+HL
Sbjct: 76  ARGLDDASYDPQRFAMDYHIIGFRECVAEVARYLVSIEGMDVQDPLRLRLMSHL 129


>UniRef50_Q8T8A9 Cluster: Hairy E(SPL) like bHLH transcription
           factor; n=1; Halocynthia roretzi|Rep: Hairy E(SPL) like
           bHLH transcription factor - Halocynthia roretzi (Sea
           squirt)
          Length = 292

 Score = 63.7 bits (148), Expect = 4e-09
 Identities = 31/51 (60%), Positives = 39/51 (76%)
 Frame = +3

Query: 108 RKVMKPMLERKRRARINRCLDELKELMVSALQSEGENVAKLEKADILELTV 260
           RK  KP++E+KRR RINRCLDELK +++ A+  E     KLEKADILE+TV
Sbjct: 14  RKTNKPIMEKKRRERINRCLDELKNIVLRAVNEE-SRPNKLEKADILEMTV 63


>UniRef50_Q6P0J1 Cluster: Hairy and enhancer of split 6; n=3; Danio
           rerio|Rep: Hairy and enhancer of split 6 - Danio rerio
           (Zebrafish) (Brachydanio rerio)
          Length = 226

 Score = 63.3 bits (147), Expect = 5e-09
 Identities = 42/121 (34%), Positives = 65/121 (53%), Gaps = 5/121 (4%)
 Frame = +3

Query: 108 RKVMKPMLERKRRARINRCLDELKELMVSALQSEGENVAKLEKADILELTVXXXXXXXXX 287
           RK  KP++E+KRRARIN  L EL+ L+     ++ +   K+E A++LE+TV         
Sbjct: 20  RKTRKPLVEKKRRARINESLQELRLLL-----ADPDAQVKMENAEVLEMTVKRVESILQN 74

Query: 288 XXXXXNPSVD---VDRFRAGFTHAANEVSRCLASIPGVDVRLGTQLMTHLGH--RLNDMQ 452
                + SV+    +RF AG+    +EV   ++S PG+D  +   L+ HL     LND +
Sbjct: 75  KAKEAD-SVNREANERFAAGYIQCMHEVHTFVSSCPGIDATIAADLLNHLLECMPLNDEE 133

Query: 453 R 455
           R
Sbjct: 134 R 134


>UniRef50_A1L3K9 Cluster: LOC100037036 protein; n=2; Xenopus|Rep:
           LOC100037036 protein - Xenopus laevis (African clawed
           frog)
          Length = 222

 Score = 62.9 bits (146), Expect = 6e-09
 Identities = 36/109 (33%), Positives = 58/109 (53%), Gaps = 2/109 (1%)
 Frame = +3

Query: 108 RKVMKPMLERKRRARINRCLDELKELMVSALQSEGENVAKLEKADILELTVXXXXXXXXX 287
           R+  KP++E++RRARIN  L EL+ ++     S+ E   K+E A++L+LTV         
Sbjct: 41  RQTRKPLVEKRRRARINESLQELRGIL-----SDNEFQTKIENAEVLDLTVKRVERILRN 95

Query: 288 XXXXXN--PSVDVDRFRAGFTHAANEVSRCLASIPGVDVRLGTQLMTHL 428
                +       +RF AG+    +EV   ++S PG+D  L  +L+ HL
Sbjct: 96  RTAEADRLQREASERFAAGYIQCMHEVHTFVSSCPGIDASLAAELLNHL 144


>UniRef50_Q8AXV5 Cluster: Hairy/enhancer-of-split related with YRPW
           motif-like protein; n=6; Clupeocephala|Rep:
           Hairy/enhancer-of-split related with YRPW motif-like
           protein - Danio rerio (Zebrafish) (Brachydanio rerio)
          Length = 310

 Score = 62.9 bits (146), Expect = 6e-09
 Identities = 40/118 (33%), Positives = 65/118 (55%), Gaps = 4/118 (3%)
 Frame = +3

Query: 108 RKVMKPMLERKRRARINRCLDELKELMVSALQSEGENVAKLEKADILELTV--XXXXXXX 281
           RK  + ++E++RR RIN  L EL+ L+ SA + +G   +KLEKA+IL++TV         
Sbjct: 44  RKKRRGIIEKRRRDRINHSLSELRRLVPSAFEKQGS--SKLEKAEILQMTVDHLKLLHAM 101

Query: 282 XXXXXXXNPSVDVDRFRAGFTHAANEVSRCLASIPGVDVR--LGTQLMTHLGHRLNDM 449
                    ++ VD    GF     EV R L+S+ GV+    +G +L++HL H  +++
Sbjct: 102 GGKGYFDARALAVDYRTLGFRECVGEVVRYLSSLEGVESSDPIGARLVSHLSHCASEL 159


>UniRef50_Q5XHC4 Cluster: LOC495039 protein; n=7; Tetrapoda|Rep:
           LOC495039 protein - Xenopus laevis (African clawed frog)
          Length = 202

 Score = 62.1 bits (144), Expect = 1e-08
 Identities = 31/73 (42%), Positives = 49/73 (67%), Gaps = 3/73 (4%)
 Frame = +3

Query: 51  IAYSLADDGPQPVSRTYQ---YRKVMKPMLERKRRARINRCLDELKELMVSALQSEGENV 221
           +A S+ +  P+P  R  +    RK +KP++E++RRARIN  L++LK L++  +  +    
Sbjct: 18  LADSMHNYQPKPGKRNQEASELRKTLKPLMEKRRRARINESLNQLKTLILPLIGKDNSRY 77

Query: 222 AKLEKADILELTV 260
           +KLEKADILE+TV
Sbjct: 78  SKLEKADILEMTV 90


>UniRef50_Q96HZ4 Cluster: Transcription cofactor HES-6; n=18;
           cellular organisms|Rep: Transcription cofactor HES-6 -
           Homo sapiens (Human)
          Length = 224

 Score = 61.3 bits (142), Expect = 2e-08
 Identities = 38/109 (34%), Positives = 56/109 (51%), Gaps = 2/109 (1%)
 Frame = +3

Query: 108 RKVMKPMLERKRRARINRCLDELKELMVSALQSEGENVAKLEKADILELTVXXXXXXXXX 287
           RK  KP++E+KRRARIN  L EL+ L+  A     E  AKLE A++LELTV         
Sbjct: 26  RKARKPLVEKKRRARINESLQELRLLLAGA-----EVQAKLENAEVLELTVRRVQGVLRG 80

Query: 288 XXXXXN--PSVDVDRFRAGFTHAANEVSRCLASIPGVDVRLGTQLMTHL 428
                    +   +RF AG+    +EV   +++   +D  +  +L+ HL
Sbjct: 81  RAREREQLQAEASERFAAGYIQCMHEVHTFVSTCQAIDATVAAELLNHL 129


>UniRef50_UPI000058443F Cluster: PREDICTED: similar to hairy E
           protein; n=1; Strongylocentrotus purpuratus|Rep:
           PREDICTED: similar to hairy E protein -
           Strongylocentrotus purpuratus
          Length = 397

 Score = 60.5 bits (140), Expect = 3e-08
 Identities = 44/123 (35%), Positives = 67/123 (54%), Gaps = 6/123 (4%)
 Frame = +3

Query: 90  SRTYQYRKVMKPMLERKRRARINRCLDELKELMVSALQSEGENVA--KLEKADILELT-- 257
           SR+++ RK  KP++E++RRARIN CL EL+ ++  AL  E  +    K EKADILE T  
Sbjct: 8   SRSHEGRKSSKPLMEKRRRARINDCLTELQTIL-DALNPENNSTRQNKREKADILEQTVK 66

Query: 258 -VXXXXXXXXXXXXXXNPSVDVDRFRAGFTHAANEVSRCLASIPG-VDVRLGTQLMTHLG 431
            V              +P+  V +FR+GF      V++ L++  G ++      LM+HL 
Sbjct: 67  LVKQLRQHGIRGNHPPDPNTQV-QFRSGFNECMATVTQFLSANNGSLNGEAKAGLMSHLA 125

Query: 432 HRL 440
           + L
Sbjct: 126 NSL 128


>UniRef50_Q5S4J7 Cluster: Enhancer of split complex m5 protein; n=2;
           Drosophila melanogaster|Rep: Enhancer of split complex
           m5 protein - Drosophila melanogaster (Fruit fly)
          Length = 178

 Score = 60.5 bits (140), Expect = 3e-08
 Identities = 33/88 (37%), Positives = 54/88 (61%)
 Frame = +3

Query: 87  VSRTYQYRKVMKPMLERKRRARINRCLDELKELMVSALQSEGENVAKLEKADILELTVXX 266
           VS+T  Y KV KP+LER+RRAR+N+CLD LK L V+  Q + + + +++KA++LE  +  
Sbjct: 12  VSKTQHYLKVKKPLLERQRRARMNKCLDTLKTL-VAEFQGD-DAILRMDKAEMLEAALVF 69

Query: 267 XXXXXXXXXXXXNPSVDVDRFRAGFTHA 350
                       +P + +D F+ G+ +A
Sbjct: 70  MRKQVVKQQAPVSP-LPMDSFKNGYMNA 96


>UniRef50_Q0P454 Cluster: Zgc:153398; n=6; Clupeocephala|Rep:
           Zgc:153398 - Danio rerio (Zebrafish) (Brachydanio rerio)
          Length = 172

 Score = 60.1 bits (139), Expect = 5e-08
 Identities = 29/53 (54%), Positives = 38/53 (71%)
 Frame = +3

Query: 102 QYRKVMKPMLERKRRARINRCLDELKELMVSALQSEGENVAKLEKADILELTV 260
           + RK +KP+LE+KRRARIN  LD LK L++     +    +KLEKADILE+TV
Sbjct: 7   ELRKTLKPLLEKKRRARINDSLDRLKALILPLTGKDNCRYSKLEKADILEMTV 59


>UniRef50_Q4H3P1 Cluster: Transcription factor protein; n=1; Ciona
           intestinalis|Rep: Transcription factor protein - Ciona
           intestinalis (Transparent sea squirt)
          Length = 258

 Score = 60.1 bits (139), Expect = 5e-08
 Identities = 28/51 (54%), Positives = 41/51 (80%)
 Frame = +3

Query: 108 RKVMKPMLERKRRARINRCLDELKELMVSALQSEGENVAKLEKADILELTV 260
           RK  KP++E+KRR RIN+CL++LK ++++A+ +E     KLEKADILE+TV
Sbjct: 14  RKTNKPIMEKKRRERINKCLEDLKSIVLTAV-AEESRPNKLEKADILEMTV 63


>UniRef50_UPI0000E48019 Cluster: PREDICTED: similar to
           hairy/enhancer of split; n=1; Strongylocentrotus
           purpuratus|Rep: PREDICTED: similar to hairy/enhancer of
           split - Strongylocentrotus purpuratus
          Length = 383

 Score = 59.7 bits (138), Expect = 6e-08
 Identities = 34/100 (34%), Positives = 51/100 (51%), Gaps = 3/100 (3%)
 Frame = +3

Query: 84  PVSRTYQYRKVMKPMLERKRRARINRCLDELKELMVSALQSEGENVAKLEKADILELTV- 260
           P    +   + +KP +E++RRARIN  L +LK L++ AL       +KLEKADILE+TV 
Sbjct: 23  PTDDQHPPSRSLKPQMEKRRRARINDSLLQLKNLVLDALNKNNPRHSKLEKADILEMTVR 82

Query: 261 --XXXXXXXXXXXXXXNPSVDVDRFRAGFTHAANEVSRCL 374
                           N   ++ +++ G+     EVSR L
Sbjct: 83  YLRSIHRQQLSGIGSHNEQANIAQYQTGYAECMREVSRYL 122


>UniRef50_UPI00000181D8 Cluster: Homolog of Brachydanio rerio "Hairy
           and enhancer of split 6.; n=1; Takifugu rubripes|Rep:
           Homolog of Brachydanio rerio "Hairy and enhancer of
           split 6. - Takifugu rubripes
          Length = 186

 Score = 59.7 bits (138), Expect = 6e-08
 Identities = 39/116 (33%), Positives = 62/116 (53%), Gaps = 4/116 (3%)
 Frame = +3

Query: 120 KPMLERKRRARINRCLDELKELMVSALQSEGENVAKLEKADILELTVXXXXXXXXXXXXX 299
           KP++E+KRRARIN+ L+EL+ L+     +E +  +KLE A++L +TV             
Sbjct: 4   KPLVEKKRRARINKSLEELRLLV-----AEPDLQSKLENAELLAMTVKRVENILQDPTPD 58

Query: 300 XNPS--VDVDRFRAGFTHAANEVSRCLASIPGVDVRLGTQLMTHL--GHRLNDMQR 455
              S     +RF AG+    ++V   +++ PGVD     +L+ HL     LND +R
Sbjct: 59  AEASSREACERFTAGYIQCMHDVHTFVSTCPGVDQTFAAELLHHLMESMPLNDQER 114


>UniRef50_UPI0000F1EAFE Cluster: PREDICTED: hypothetical protein;
           n=1; Danio rerio|Rep: PREDICTED: hypothetical protein -
           Danio rerio
          Length = 195

 Score = 59.3 bits (137), Expect = 8e-08
 Identities = 26/54 (48%), Positives = 40/54 (74%)
 Frame = +3

Query: 99  YQYRKVMKPMLERKRRARINRCLDELKELMVSALQSEGENVAKLEKADILELTV 260
           ++ RK +KP++E++RRARIN  L+ LK L++  +  +    +KLEKADILE+TV
Sbjct: 27  HELRKTLKPLMEKRRRARINDSLNHLKTLILPLVGKDASRYSKLEKADILEMTV 80


>UniRef50_UPI0000D5795D Cluster: PREDICTED: similar to CG11194-PA;
           n=1; Tribolium castaneum|Rep: PREDICTED: similar to
           CG11194-PA - Tribolium castaneum
          Length = 363

 Score = 59.3 bits (137), Expect = 8e-08
 Identities = 43/112 (38%), Positives = 60/112 (53%), Gaps = 5/112 (4%)
 Frame = +3

Query: 108 RKVMKPMLERKRRARINRCLDELKELMVSALQSEGENVAKLEKADILELTV--XXXXXXX 281
           RK  + ++E+KRR RIN  L ELK L+ SA + +G   AKLEKA+IL++TV         
Sbjct: 116 RKKRRGVIEKKRRDRINMSLSELKRLVPSAFEKQGS--AKLEKAEILQMTVDHLKMLHAK 173

Query: 282 XXXXXXXNP-SVDVDRFRAGFTHAANEVSRCLASIPGVDVR--LGTQLMTHL 428
                  +P    +D    GF     EV+R L  I G+DV+  L  +L +HL
Sbjct: 174 GLDAFTYDPHKYAMDYHGMGFRECVAEVARYLERIEGLDVQNPLRLRLTSHL 225


>UniRef50_UPI0000D563AB Cluster: PREDICTED: similar to CG10446-PA;
           n=1; Tribolium castaneum|Rep: PREDICTED: similar to
           CG10446-PA - Tribolium castaneum
          Length = 232

 Score = 59.3 bits (137), Expect = 8e-08
 Identities = 39/117 (33%), Positives = 62/117 (52%), Gaps = 5/117 (4%)
 Frame = +3

Query: 93  RTYQYRKVMKPMLERKRRARINRCLDELKELMVSALQSEGENVAKLEKADILELTVXXXX 272
           R  + R+  KP++E++RRARIN+ L  LK L++ + +++    +KLEKADILELTV    
Sbjct: 7   RASEPRRANKPLMEKRRRARINQSLAALKTLILDSAKADNTKHSKLEKADILELTVRHFQ 66

Query: 273 XXXXXXXXXXNPSVDVDRFRAGFTHAANEVSRCL-----ASIPGVDVRLGTQLMTHL 428
                          V +++AG+     EV R L      ++  VD  +  +L+ HL
Sbjct: 67  RHRSLDIK------GVHQYKAGYADCVREVQRYLDTPDAQTMTVVDAGVRQRLLRHL 117


>UniRef50_Q6YID3 Cluster: Hairy and enhancer of split; n=1;
           Helobdella robusta|Rep: Hairy and enhancer of split -
           Helobdella robusta (Leech)
          Length = 435

 Score = 59.3 bits (137), Expect = 8e-08
 Identities = 29/58 (50%), Positives = 40/58 (68%)
 Frame = +3

Query: 87  VSRTYQYRKVMKPMLERKRRARINRCLDELKELMVSALQSEGENVAKLEKADILELTV 260
           VSR  Q RK+ KP++E+KRR RIN  LD+LK L++ A   +     ++EKADILE+ V
Sbjct: 5   VSRD-QLRKIKKPIIEKKRRERINESLDQLKNLVLEATNKDASMYNRMEKADILEMAV 61


>UniRef50_Q4H3E4 Cluster: Transcription factor protein; n=1; Ciona
           intestinalis|Rep: Transcription factor protein - Ciona
           intestinalis (Transparent sea squirt)
          Length = 248

 Score = 59.3 bits (137), Expect = 8e-08
 Identities = 37/112 (33%), Positives = 59/112 (52%), Gaps = 5/112 (4%)
 Frame = +3

Query: 108 RKVMKPMLERKRRARINRCLDELKELMVSALQSEGENVAKLEKADILELTVXXXXXXXXX 287
           RK  + ++E++RR RIN  L EL+ ++ +A +  G   +KLEKA+IL+LTV         
Sbjct: 29  RKKRRGVIEKRRRDRINNSLSELRRMIPAASEKHGS--SKLEKAEILQLTVEHLKTLQSA 86

Query: 288 XXXXXNPSVD-----VDRFRAGFTHAANEVSRCLASIPGVDVRLGTQLMTHL 428
                 P +D     VD    GF    +EV+R + S+ G+   +   L++HL
Sbjct: 87  ISKGYFPFMDVRTMAVDYHSFGFRECVSEVARYMISMDGIQSSVRENLLSHL 138


>UniRef50_Q9VJ16 Cluster: CG10446-PA; n=4; Diptera|Rep: CG10446-PA -
           Drosophila melanogaster (Fruit fly)
          Length = 507

 Score = 58.8 bits (136), Expect = 1e-07
 Identities = 40/98 (40%), Positives = 61/98 (62%), Gaps = 7/98 (7%)
 Frame = +3

Query: 108 RKVMKPMLERKRRARINRCLDELKELMVSALQSE----GENVA---KLEKADILELTVXX 266
           ++  KP++E++RRARIN+ L  LK L++ + +++    GE  A   KLEKADILELTV  
Sbjct: 51  KRTNKPLMEKRRRARINQSLAILKALILESTKTQNAKNGEGQAKHTKLEKADILELTV-- 108

Query: 267 XXXXXXXXXXXXNPSVDVDRFRAGFTHAANEVSRCLAS 380
                       +P+  V+++RAG+T  A EV+R LA+
Sbjct: 109 --RHFQRHRNLDDPT--VNKYRAGYTDCAREVARYLAT 142


>UniRef50_UPI00015B46B7 Cluster: PREDICTED: similar to GA10322-PA;
           n=1; Nasonia vitripennis|Rep: PREDICTED: similar to
           GA10322-PA - Nasonia vitripennis
          Length = 715

 Score = 58.4 bits (135), Expect = 1e-07
 Identities = 35/85 (41%), Positives = 50/85 (58%)
 Frame = +3

Query: 120 KPMLERKRRARINRCLDELKELMVSALQSEGENVAKLEKADILELTVXXXXXXXXXXXXX 299
           KP++E++RRARIN+ L  LK L++ + + E    +KLEKADILELTV             
Sbjct: 330 KPLMEKRRRARINQSLAALKALILDSARLENTKHSKLEKADILELTV----RHLQRQRSL 385

Query: 300 XNPSVDVDRFRAGFTHAANEVSRCL 374
             P   + R++AG+   + EVSR L
Sbjct: 386 AQPG--LSRYKAGYQDCSREVSRYL 408


>UniRef50_UPI000059FC8B Cluster: PREDICTED: similar to
           hairy/enhancer-of-split related with YRPW motif 2; n=1;
           Canis lupus familiaris|Rep: PREDICTED: similar to
           hairy/enhancer-of-split related with YRPW motif 2 -
           Canis familiaris
          Length = 424

 Score = 58.0 bits (134), Expect = 2e-07
 Identities = 38/111 (34%), Positives = 61/111 (54%), Gaps = 4/111 (3%)
 Frame = +3

Query: 108 RKVMKPMLERKRRARINRCLDELKELMVSALQSEGENVAKLEKADILELTV--XXXXXXX 281
           RK  + ++E++RR RIN  L EL+ L+ +A + +G   AKLEKA+IL++TV         
Sbjct: 265 RKKRRGIIEKRRRDRINNSLSELRRLVPTAFEKQGS--AKLEKAEILQMTVDHLKMLQAT 322

Query: 282 XXXXXXXNPSVDVDRFRAGFTHAANEVSRCLASIPGVDVR--LGTQLMTHL 428
                    ++ +D    GF     EV+R L+S+ G+D    L  +L++HL
Sbjct: 323 GGKGYFDAHALALDFMSIGFRECLGEVARYLSSVEGLDSSDPLRARLVSHL 373


>UniRef50_UPI00005846BD Cluster: PREDICTED: similar to Hey1 protein;
           n=1; Strongylocentrotus purpuratus|Rep: PREDICTED:
           similar to Hey1 protein - Strongylocentrotus purpuratus
          Length = 317

 Score = 58.0 bits (134), Expect = 2e-07
 Identities = 40/115 (34%), Positives = 65/115 (56%), Gaps = 8/115 (6%)
 Frame = +3

Query: 108 RKVMKPMLERKRRARINRCLDELKELMVSALQSEGENVAKLEKADILELTV-XXXXXXXX 284
           RK  + ++E++RR RIN  L EL+ L+ +A + +G   AKLEKA+IL++TV         
Sbjct: 27  RKKRRGIIEKRRRDRINNSLTELRRLVPAAFEKQGS--AKLEKAEILQMTVDHLKYLHAK 84

Query: 285 XXXXXXNP-----SVDVDRFRAGFTHAANEVSRCLASIPGVDVR--LGTQLMTHL 428
                 +P     +  +D    GF   A+EV+R L ++ G+D++  L  +LM+HL
Sbjct: 85  GIDGSFHPYGEAHAYAMDYRVLGFRECASEVARYLVTVEGMDIQDPLRLRLMSHL 139


>UniRef50_Q7Q509 Cluster: ENSANGP00000020858; n=1; Anopheles gambiae
           str. PEST|Rep: ENSANGP00000020858 - Anopheles gambiae
           str. PEST
          Length = 202

 Score = 58.0 bits (134), Expect = 2e-07
 Identities = 49/156 (31%), Positives = 78/156 (50%), Gaps = 31/156 (19%)
 Frame = +3

Query: 81  QPVSRTYQYRKVMKPMLERKRRARINRCLDELKELMVSALQSE---GENVAK-------- 227
           +PV R+   R+  KP++E++RRARIN CL+ELK L++ A++ +   G  VA+        
Sbjct: 27  EPVKRSSDNRRSNKPIMEKRRRARINNCLNELKTLILDAMKKDSFSGSFVAQIALTIINV 86

Query: 228 -----------------LEKADILELTV---XXXXXXXXXXXXXXNPSVDVDRFRAGFTH 347
                            LEKADILE+TV                 +PSV +++F+AGF  
Sbjct: 87  SPLFLLSSTSQPARHSKLEKADILEMTVKHLENLQRQQTAMSQATDPSV-MNKFKAGFNE 145

Query: 348 AANEVSRCLASIPGVDVRLGTQLMTHLGHRLNDMQR 455
            A EV R     P ++  +  +L+ HL + +N + +
Sbjct: 146 CAQEVGR----FPELEPHVKRRLLQHLNNCINGVNK 177


>UniRef50_A7RYX3 Cluster: Predicted protein; n=1; Nematostella
           vectensis|Rep: Predicted protein - Nematostella
           vectensis
          Length = 270

 Score = 58.0 bits (134), Expect = 2e-07
 Identities = 28/51 (54%), Positives = 38/51 (74%)
 Frame = +3

Query: 108 RKVMKPMLERKRRARINRCLDELKELMVSALQSEGENVAKLEKADILELTV 260
           R++MKP+ ER RR RIN  L ELK L++SAL  +    +++EKADILE+TV
Sbjct: 23  RRIMKPITERLRRERINSSLKELKFLVLSALGQDVSRYSRMEKADILEMTV 73


>UniRef50_Q9UBP5 Cluster: Hairy/enhancer-of-split related with YRPW
           motif protein 2; n=20; Euteleostomi|Rep:
           Hairy/enhancer-of-split related with YRPW motif protein
           2 - Homo sapiens (Human)
          Length = 337

 Score = 58.0 bits (134), Expect = 2e-07
 Identities = 38/111 (34%), Positives = 61/111 (54%), Gaps = 4/111 (3%)
 Frame = +3

Query: 108 RKVMKPMLERKRRARINRCLDELKELMVSALQSEGENVAKLEKADILELTV--XXXXXXX 281
           RK  + ++E++RR RIN  L EL+ L+ +A + +G   AKLEKA+IL++TV         
Sbjct: 49  RKKRRGIIEKRRRDRINNSLSELRRLVPTAFEKQGS--AKLEKAEILQMTVDHLKMLQAT 106

Query: 282 XXXXXXXNPSVDVDRFRAGFTHAANEVSRCLASIPGVDVR--LGTQLMTHL 428
                    ++ +D    GF     EV+R L+S+ G+D    L  +L++HL
Sbjct: 107 GGKGYFDAHALAMDFMSIGFRECLTEVARYLSSVEGLDSSDPLRVRLVSHL 157


>UniRef50_A3KQ57 Cluster: Hairy and enhancer of split related-7;
           n=3; Danio rerio|Rep: Hairy and enhancer of split
           related-7 - Danio rerio (Zebrafish) (Brachydanio rerio)
          Length = 206

 Score = 57.6 bits (133), Expect = 2e-07
 Identities = 34/109 (31%), Positives = 54/109 (49%)
 Frame = +3

Query: 108 RKVMKPMLERKRRARINRCLDELKELMVSALQSEGENVAKLEKADILELTVXXXXXXXXX 287
           RK++KP +ER+RR R+NR L+ LK L++   +    N  +LEKA+ILE TV         
Sbjct: 14  RKLLKPQVERRRRERMNRSLENLKLLLLQGPEHNQPNQRRLEKAEILEYTV--LFLQKAN 71

Query: 288 XXXXXNPSVDVDRFRAGFTHAANEVSRCLASIPGVDVRLGTQLMTHLGH 434
                    +  +F  GF+    + +R L    G++  + + L   L H
Sbjct: 72  KASKEEEGEEKSQFMEGFSSCLQKAARFLLEEGGLEGSVTSMLCQRLAH 120


>UniRef50_Q7T3J0 Cluster: Hairy and enhancer of split 5; n=3; Danio
           rerio|Rep: Hairy and enhancer of split 5 - Danio rerio
           (Zebrafish) (Brachydanio rerio)
          Length = 149

 Score = 56.4 bits (130), Expect = 6e-07
 Identities = 26/50 (52%), Positives = 37/50 (74%)
 Frame = +3

Query: 111 KVMKPMLERKRRARINRCLDELKELMVSALQSEGENVAKLEKADILELTV 260
           K+ KP++E+ RR RIN C+++LK ++    Q +  N AKLEKADILE+TV
Sbjct: 19  KLRKPVVEKMRRDRINNCIEQLKSMLEKEFQQQDPN-AKLEKADILEMTV 67


>UniRef50_Q9Y5J3 Cluster: Hairy/enhancer-of-split related with YRPW
           motif protein 1; n=33; Eumetazoa|Rep:
           Hairy/enhancer-of-split related with YRPW motif protein
           1 - Homo sapiens (Human)
          Length = 304

 Score = 56.4 bits (130), Expect = 6e-07
 Identities = 39/113 (34%), Positives = 61/113 (53%), Gaps = 4/113 (3%)
 Frame = +3

Query: 108 RKVMKPMLERKRRARINRCLDELKELMVSALQSEGENVAKLEKADILELTV--XXXXXXX 281
           RK  + ++E++RR RIN  L EL+ L+ SA + +G   AKLEKA+IL++TV         
Sbjct: 50  RKRRRGIIEKRRRDRINNSLSELRRLVPSAFEKQGS--AKLEKAEILQMTVDHLKMLHTA 107

Query: 282 XXXXXXXNPSVDVDRFRAGFTHAANEVSRCLASIPGVDVR--LGTQLMTHLGH 434
                    ++ +D    GF     EV+R L+ I G+D    L  +L++HL +
Sbjct: 108 GGKGYFDAHALAMDYRSLGFRECLAEVARYLSIIEGLDASDPLRVRLVSHLNN 160


>UniRef50_A7S152 Cluster: Predicted protein; n=1; Nematostella
           vectensis|Rep: Predicted protein - Nematostella
           vectensis
          Length = 170

 Score = 55.6 bits (128), Expect = 1e-06
 Identities = 32/55 (58%), Positives = 42/55 (76%), Gaps = 5/55 (9%)
 Frame = +3

Query: 111 KVMKPMLERKRRARINRCLDELKELMVSAL-----QSEGENVAKLEKADILELTV 260
           K  KP+LER+RRARIN  L+ELK L++S+L     Q+E +N  K+EKA+ILELTV
Sbjct: 20  KSSKPLLERQRRARINHSLNELKTLVLSSLYQNCPQAE-QNCEKMEKAEILELTV 73


>UniRef50_A7RYX2 Cluster: Predicted protein; n=1; Nematostella
           vectensis|Rep: Predicted protein - Nematostella
           vectensis
          Length = 233

 Score = 55.2 bits (127), Expect = 1e-06
 Identities = 25/51 (49%), Positives = 37/51 (72%)
 Frame = +3

Query: 108 RKVMKPMLERKRRARINRCLDELKELMVSALQSEGENVAKLEKADILELTV 260
           RK  KP++E+ RR RIN  L+E+K L++ +L  +    +K+EKADILE+TV
Sbjct: 24  RKTKKPLMEKLRRDRINNSLNEMKLLVLESLNKDVSRYSKMEKADILEMTV 74


>UniRef50_Q8UW74 Cluster: HES-related 1A; n=4; Xenopus|Rep:
           HES-related 1A - Xenopus laevis (African clawed frog)
          Length = 180

 Score = 54.8 bits (126), Expect = 2e-06
 Identities = 35/117 (29%), Positives = 61/117 (52%)
 Frame = +3

Query: 75  GPQPVSRTYQYRKVMKPMLERKRRARINRCLDELKELMVSALQSEGENVAKLEKADILEL 254
           G   V     +RK++KP++E++RR RIN  L++L+  +   L+SE     K+EKA+ILE 
Sbjct: 3   GTSEVKPMETHRKLLKPLVEKRRRERINNSLEKLRIFLFQTLKSEKLKNPKVEKAEILEC 62

Query: 255 TVXXXXXXXXXXXXXXNPSVDVDRFRAGFTHAANEVSRCLASIPGVDVRLGTQLMTH 425
           TV                +VD + +++GF H        + S P ++  +  +L++H
Sbjct: 63  TV--QFLQSRKLLPLDREAVDKE-YQSGFQHCLETTLHFMNSKPDMN-GVTKELLSH 115


>UniRef50_Q4RKD6 Cluster: Chromosome 21 SCAF15029, whole genome
           shotgun sequence; n=2; Tetraodontidae|Rep: Chromosome 21
           SCAF15029, whole genome shotgun sequence - Tetraodon
           nigroviridis (Green puffer)
          Length = 374

 Score = 54.4 bits (125), Expect = 2e-06
 Identities = 37/107 (34%), Positives = 58/107 (54%), Gaps = 4/107 (3%)
 Frame = +3

Query: 120 KPMLERKRRARINRCLDELKELMVSALQSEGENVAKLEKADILELTV--XXXXXXXXXXX 293
           + ++E++RR RIN CL EL+ L+ SA + +G   AKLEKA+IL++TV             
Sbjct: 107 RQIIEKRRRDRINNCLSELRRLVPSAFEKQGS--AKLEKAEILQMTVDHLKMLHAAGGKG 164

Query: 294 XXXNPSVDVDRFRAGFTHAANEVSRCLASIPGVDVR--LGTQLMTHL 428
                ++ +D    GF     E +R L+ I G+D    L  +L++HL
Sbjct: 165 YFDAHALAMDYRGLGFRECLAETARYLSIIEGLDGADPLRLRLVSHL 211


>UniRef50_Q4S814 Cluster: Chromosome 9 SCAF14710, whole genome
           shotgun sequence; n=3; Euteleostomi|Rep: Chromosome 9
           SCAF14710, whole genome shotgun sequence - Tetraodon
           nigroviridis (Green puffer)
          Length = 182

 Score = 53.6 bits (123), Expect = 4e-06
 Identities = 25/50 (50%), Positives = 37/50 (74%)
 Frame = +3

Query: 111 KVMKPMLERKRRARINRCLDELKELMVSALQSEGENVAKLEKADILELTV 260
           ++ KP++E+ RR RIN C+D+LK ++    Q +  N +KLEKADILE+TV
Sbjct: 49  QLRKPVVEKMRRDRINSCIDQLKVILEKEFQKQEPN-SKLEKADILEMTV 97


>UniRef50_Q4QRL6 Cluster: Hairy-related 12; n=2; Danio rerio|Rep:
           Hairy-related 12 - Danio rerio (Zebrafish) (Brachydanio
           rerio)
          Length = 155

 Score = 53.6 bits (123), Expect = 4e-06
 Identities = 26/50 (52%), Positives = 35/50 (70%)
 Frame = +3

Query: 111 KVMKPMLERKRRARINRCLDELKELMVSALQSEGENVAKLEKADILELTV 260
           K+ KP++E+ RR RIN C+D+LK L+     S   +  KLEKADILE+TV
Sbjct: 23  KLRKPIVEKMRRDRINTCIDQLKSLLEKEFHSHDPS-TKLEKADILEMTV 71


>UniRef50_Q6V6Y9 Cluster: Hairy H protein; n=2; Coelomata|Rep: Hairy
           H protein - Branchiostoma floridae (Florida lancelet)
           (Amphioxus)
          Length = 66

 Score = 53.6 bits (123), Expect = 4e-06
 Identities = 27/57 (47%), Positives = 41/57 (71%), Gaps = 2/57 (3%)
 Frame = +3

Query: 90  SRTYQYRKVMKPMLERKRRARINRCLDELKELMVSALQSE--GENVAKLEKADILEL 254
           S  +Q RK  KP++E++RRARIN  L+ELK L++  ++ +    + +KLEKADILE+
Sbjct: 10  SSPHQGRKSSKPLMEKRRRARINSSLNELKNLILGTVKDDINAPHHSKLEKADILEI 66


>UniRef50_UPI0000D5710A Cluster: PREDICTED: similar to CG10446-PA;
           n=1; Tribolium castaneum|Rep: PREDICTED: similar to
           CG10446-PA - Tribolium castaneum
          Length = 177

 Score = 53.2 bits (122), Expect = 5e-06
 Identities = 28/58 (48%), Positives = 41/58 (70%), Gaps = 8/58 (13%)
 Frame = +3

Query: 111 KVMKPMLERKRRARINRCLDELKELMV--------SALQSEGENVAKLEKADILELTV 260
           +V KP++E+KRRARIN  L+ LK++++        S+ +  G+  AKLEKADILE+TV
Sbjct: 47  RVRKPLMEKKRRARINDSLEALKQILLDSKTTLKESSGKKSGQRTAKLEKADILEMTV 104


>UniRef50_Q9NQ87 Cluster: Hairy/enhancer-of-split related with YRPW
           motif-like protein; n=13; Amniota|Rep:
           Hairy/enhancer-of-split related with YRPW motif-like
           protein - Homo sapiens (Human)
          Length = 328

 Score = 52.8 bits (121), Expect = 7e-06
 Identities = 39/128 (30%), Positives = 63/128 (49%), Gaps = 5/128 (3%)
 Frame = +3

Query: 84  PVSRTYQYRKVMKPMLERKRRARINRCLDELKELMVSALQSEGENVAKLEKADILELTV- 260
           P S   Q RK  + ++E++RR RIN  L EL+ L+ +A + +G   +KLEKA++L++TV 
Sbjct: 36  PSSSQMQARKKHRGIIEKRRRDRINSSLSELRRLVPTAFEKQGS--SKLEKAEVLQMTVD 93

Query: 261 -XXXXXXXXXXXXXXNPSVDVDRFRAGFTHAANEVSRCLASIPGVDVR---LGTQLMTHL 428
                            ++ VD    GF     EV R L  + G   R   +  +L++HL
Sbjct: 94  HLKMLHATGGTGFFDARALAVDFRSIGFRECLTEVIRYLGVLEGPSSRADPVRIRLLSHL 153

Query: 429 GHRLNDMQ 452
                +M+
Sbjct: 154 NSYAAEME 161


>UniRef50_Q9W7B6 Cluster: BHLH-WRPW transcription factor ESR-5; n=2;
           Xenopus laevis|Rep: BHLH-WRPW transcription factor ESR-5
           - Xenopus laevis (African clawed frog)
          Length = 203

 Score = 52.4 bits (120), Expect = 9e-06
 Identities = 37/120 (30%), Positives = 56/120 (46%), Gaps = 3/120 (2%)
 Frame = +3

Query: 90  SRTYQYRKVMKPMLERKRRARINRCLDELKELMVSALQSEGENVAKLEKADILELTVXXX 269
           S T+  RK++KP++E++RR RINR L E++ L+     ++     K+EKA+ILEL V   
Sbjct: 7   SDTFPSRKILKPVVEKQRRDRINRSLGEMRILLFQLTGNQKLQNPKMEKAEILELAVIYI 66

Query: 270 XXXXXXXXXXXN--PSVDVDRFRAGFTHAANEVSRCLASI-PGVDVRLGTQLMTHLGHRL 440
                      N   S     + +GF    +     ++ I P         L THL  RL
Sbjct: 67  RNVTRMKTHDPNKWASPAEKMYVSGFRECLDRTEDFISEISPKARAVFLDNLQTHLQQRL 126


>UniRef50_Q9YI65 Cluster: Basic-helix-loop-helix transcription
           factor hairy2b; n=2; Xenopus|Rep: Basic-helix-loop-helix
           transcription factor hairy2b - Xenopus laevis (African
           clawed frog)
          Length = 274

 Score = 52.0 bits (119), Expect = 1e-05
 Identities = 31/91 (34%), Positives = 48/91 (52%), Gaps = 3/91 (3%)
 Frame = +3

Query: 186 MVSALQSEGENVAKLEKADILELTVXXXXXXXXXXXXXX---NPSVDVDRFRAGFTHAAN 356
           M+  +  +    +KLEKADILE+TV                 +PSV + ++RAGF    N
Sbjct: 35  MIPCISPQSSRHSKLEKADILEMTVKHLRNLQRVQMTAALTSDPSV-LGKYRAGFNECTN 93

Query: 357 EVSRCLASIPGVDVRLGTQLMTHLGHRLNDM 449
           EV+R L++  GV+  + T+L+ HL   L  +
Sbjct: 94  EVTRFLSTCEGVNTEVRTRLLGHLSSCLGQI 124


>UniRef50_UPI00015B47F2 Cluster: PREDICTED: similar to RT01017p;
           n=1; Nasonia vitripennis|Rep: PREDICTED: similar to
           RT01017p - Nasonia vitripennis
          Length = 306

 Score = 51.6 bits (118), Expect = 2e-05
 Identities = 38/112 (33%), Positives = 58/112 (51%), Gaps = 5/112 (4%)
 Frame = +3

Query: 108 RKVMKPMLERKRRARINRCLDELKELMVSALQSEGENVAKLEKADILELTV---XXXXXX 278
           RK  + M+E+KRR RIN  L EL+ L+ +A  +   +  KLEKA+IL+LTV         
Sbjct: 130 RKRRRGMIEKKRRDRINASLGELRRLVPAA--ARDPHSGKLEKAEILQLTVEHLRTLRNK 187

Query: 279 XXXXXXXXNPSVDVDRFRAGFTHAANEVSRCLASIPGVDVR--LGTQLMTHL 428
                   +  + +D    G+     EV R L ++ G+D R  L  +L++HL
Sbjct: 188 VLRDLGYDSTKLAMDYHAVGWGECVAEVGRYLVTMEGLDERDPLRLRLLSHL 239


>UniRef50_Q5TYJ1 Cluster: ENSANGP00000029214; n=1; Anopheles gambiae
           str. PEST|Rep: ENSANGP00000029214 - Anopheles gambiae
           str. PEST
          Length = 141

 Score = 38.7 bits (86), Expect(2) = 2e-05
 Identities = 15/30 (50%), Positives = 25/30 (83%)
 Frame = +3

Query: 120 KPMLERKRRARINRCLDELKELMVSALQSE 209
           KP++E+KRRARIN  L++LK L++ A++ +
Sbjct: 4   KPIMEKKRRARINNYLNDLKSLLLDAMKKD 33



 Score = 32.3 bits (70), Expect(2) = 2e-05
 Identities = 22/72 (30%), Positives = 35/72 (48%), Gaps = 3/72 (4%)
 Frame = +3

Query: 222 AKLEKADILELTV---XXXXXXXXXXXXXXNPSVDVDRFRAGFTHAANEVSRCLASIPGV 392
           +KLEKADIL+LTV                 +P+V  ++F  G+    +E+ +   S+  V
Sbjct: 67  SKLEKADILDLTVKHLQDVERRRLNVAMAVDPTVP-EKFANGYRECIDEIGKYFDSLGSV 125

Query: 393 DVRLGTQLMTHL 428
           D  L  ++  HL
Sbjct: 126 DEGLKARVRKHL 137


>UniRef50_Q96HZ4-2 Cluster: Isoform 2 of Q96HZ4 ; n=2;
           Catarrhini|Rep: Isoform 2 of Q96HZ4 - Homo sapiens
           (Human)
          Length = 219

 Score = 50.8 bits (116), Expect = 3e-05
 Identities = 28/51 (54%), Positives = 35/51 (68%)
 Frame = +3

Query: 108 RKVMKPMLERKRRARINRCLDELKELMVSALQSEGENVAKLEKADILELTV 260
           RK  KP++E+KRRARIN  L EL+ L+  A     E  AKLE A++LELTV
Sbjct: 26  RKARKPLVEKKRRARINESLQELRLLLAGA-----EVQAKLENAEVLELTV 71


>UniRef50_A3KQ56 Cluster: Hairy-related 1; n=3; Danio rerio|Rep:
           Hairy-related 1 - Danio rerio (Zebrafish) (Brachydanio
           rerio)
          Length = 328

 Score = 50.8 bits (116), Expect = 3e-05
 Identities = 26/52 (50%), Positives = 41/52 (78%), Gaps = 1/52 (1%)
 Frame = +3

Query: 108 RKVMKPMLERKRRARINRCLDELKELMV-SALQSEGENVAKLEKADILELTV 260
           ++++KP++E+KRR RIN+ L+EL+ L++ + L S  +N  KLEKA+ILEL V
Sbjct: 13  KRILKPVIEKKRRDRINQRLEELRTLLLDNTLDSRLQN-PKLEKAEILELAV 63


>UniRef50_Q9BYE0 Cluster: Transcription factor HES-7; n=11;
           Theria|Rep: Transcription factor HES-7 - Homo sapiens
           (Human)
          Length = 225

 Score = 50.8 bits (116), Expect = 3e-05
 Identities = 23/50 (46%), Positives = 36/50 (72%)
 Frame = +3

Query: 111 KVMKPMLERKRRARINRCLDELKELMVSALQSEGENVAKLEKADILELTV 260
           K++KP++E++RR RINR L+EL+ L++   + +     KLEKA+ILE  V
Sbjct: 14  KMLKPLVEKRRRDRINRSLEELRLLLLERTRDQNLRNPKLEKAEILEFAV 63


>UniRef50_UPI00015A7FE8 Cluster: hairy-related 1; n=3;
           Euteleostomi|Rep: hairy-related 1 - Danio rerio
          Length = 63

 Score = 50.4 bits (115), Expect = 4e-05
 Identities = 26/52 (50%), Positives = 41/52 (78%), Gaps = 1/52 (1%)
 Frame = +3

Query: 108 RKVMKPMLERKRRARINRCLDELKELMV-SALQSEGENVAKLEKADILELTV 260
           ++++KP++E+KRR RIN+ L+EL+ L++ + L S  +N  KLEKA+ILEL V
Sbjct: 13  QRILKPVIEKKRRDRINQRLEELRTLLLDNTLDSRLQN-PKLEKAEILELAV 63


>UniRef50_Q53U32 Cluster: Enhancer of split related protein 3/7b;
           n=3; Xenopus|Rep: Enhancer of split related protein 3/7b
           - Xenopus laevis (African clawed frog)
          Length = 159

 Score = 50.4 bits (115), Expect = 4e-05
 Identities = 25/50 (50%), Positives = 36/50 (72%)
 Frame = +3

Query: 111 KVMKPMLERKRRARINRCLDELKELMVSALQSEGENVAKLEKADILELTV 260
           K+ KP++E+ RR RIN  +++LK L+ +    +  NV KLEKADILE+TV
Sbjct: 20  KLRKPVVEKMRRDRINSSIEQLKVLLENVFHQQEPNV-KLEKADILEMTV 68


>UniRef50_Q2TP33 Cluster: Her5; n=1; Oryzias latipes|Rep: Her5 -
           Oryzias latipes (Medaka fish) (Japanese ricefish)
          Length = 192

 Score = 50.4 bits (115), Expect = 4e-05
 Identities = 25/51 (49%), Positives = 35/51 (68%)
 Frame = +3

Query: 108 RKVMKPMLERKRRARINRCLDELKELMVSALQSEGENVAKLEKADILELTV 260
           R++ KP++ER+RR RIN  L+ L+ LMV   Q+E     K+EKA+ILE  V
Sbjct: 16  RRMSKPLMERRRRERINHSLETLRLLMVKHTQNEKLKNPKVEKAEILESVV 66


>UniRef50_Q4W593 Cluster: ESR4; n=3; Xenopus|Rep: ESR4 - Xenopus
           tropicalis (Western clawed frog) (Silurana tropicalis)
          Length = 243

 Score = 50.0 bits (114), Expect = 5e-05
 Identities = 23/51 (45%), Positives = 36/51 (70%)
 Frame = +3

Query: 108 RKVMKPMLERKRRARINRCLDELKELMVSALQSEGENVAKLEKADILELTV 260
           +++MKP++E++RR RIN+ L+ L+ L++ A   E     K EKADIL+ TV
Sbjct: 25  KRLMKPVIEKRRRDRINQSLEHLRTLLLEATHDETLKNPKAEKADILKKTV 75


>UniRef50_O16853 Cluster: Lin-22; n=2; Caenorhabditis|Rep: Lin-22 -
           Caenorhabditis elegans
          Length = 173

 Score = 50.0 bits (114), Expect = 5e-05
 Identities = 22/47 (46%), Positives = 33/47 (70%)
 Frame = +3

Query: 120 KPMLERKRRARINRCLDELKELMVSALQSEGENVAKLEKADILELTV 260
           KP++E+KRRARIN+ L +LK++++          +K EKADILE+ V
Sbjct: 26  KPLMEKKRRARINKSLSQLKQILIQDEHKNSIQHSKWEKADILEMAV 72


>UniRef50_Q2TP34 Cluster: Her1-11; n=1; Oryzias latipes|Rep: Her1-11
           - Oryzias latipes (Medaka fish) (Japanese ricefish)
          Length = 269

 Score = 49.6 bits (113), Expect = 6e-05
 Identities = 36/118 (30%), Positives = 58/118 (49%), Gaps = 3/118 (2%)
 Frame = +3

Query: 108 RKVMKPMLERKRRARINRCLDELKELMVSALQSEGENVAKLEKADILELTVXXXXXXXXX 287
           ++++KP++E+KRR RIN+ L EL+ L+++       +  KLEKA+IL+L V         
Sbjct: 15  KRILKPVVEKKRRDRINQSLAELRSLLLNVTSDPRLHNPKLEKAEILDLAVEYLKKWTDR 74

Query: 288 XXXXXNPSVD---VDRFRAGFTHAANEVSRCLASIPGVDVRLGTQLMTHLGHRLNDMQ 452
                  S     +    AGF H   +VS+  + +  V     T+LM  L H    +Q
Sbjct: 75  KNARDAESSAPPLLSTETAGFQH---QVSQLTSFMHKVTPAQRTRLMETLRHHAESLQ 129


>UniRef50_A7SMU2 Cluster: Predicted protein; n=1; Nematostella
           vectensis|Rep: Predicted protein - Nematostella
           vectensis
          Length = 481

 Score = 48.4 bits (110), Expect = 1e-04
 Identities = 25/45 (55%), Positives = 34/45 (75%)
 Frame = +3

Query: 126 MLERKRRARINRCLDELKELMVSALQSEGENVAKLEKADILELTV 260
           ++E++RR RIN CL EL +L+ SA Q+  +   KLEKA+ILELTV
Sbjct: 52  VIEKRRRDRINSCLSELAQLIPSA-QNGKQGSGKLEKAEILELTV 95


>UniRef50_Q6QB00 Cluster: Her/Hey-like protein; n=2;
           Clupeocephala|Rep: Her/Hey-like protein - Danio rerio
           (Zebrafish) (Brachydanio rerio)
          Length = 270

 Score = 48.0 bits (109), Expect = 2e-04
 Identities = 25/49 (51%), Positives = 35/49 (71%)
 Frame = +3

Query: 114 VMKPMLERKRRARINRCLDELKELMVSALQSEGENVAKLEKADILELTV 260
           V   ++E++RR RINRCL+EL + +  AL    +N  KLEKA+ILE+TV
Sbjct: 62  VSHKVIEKRRRDRINRCLNELGKTVPMALAK--QNSGKLEKAEILEMTV 108


>UniRef50_Q5D212 Cluster: Hairy and enhancer of split 5; n=10;
           Tetrapoda|Rep: Hairy and enhancer of split 5 - Gallus
           gallus (Chicken)
          Length = 157

 Score = 47.2 bits (107), Expect = 3e-04
 Identities = 24/50 (48%), Positives = 35/50 (70%)
 Frame = +3

Query: 111 KVMKPMLERKRRARINRCLDELKELMVSALQSEGENVAKLEKADILELTV 260
           ++ KP++E+ RR RIN  +++LK L+    Q    N +KLEKADILE+TV
Sbjct: 18  RLRKPIVEKLRRDRINSSIEQLKLLLEKEFQRHQPN-SKLEKADILEMTV 66


>UniRef50_Q4S832 Cluster: Chromosome 9 SCAF14710, whole genome
           shotgun sequence; n=1; Tetraodon nigroviridis|Rep:
           Chromosome 9 SCAF14710, whole genome shotgun sequence -
           Tetraodon nigroviridis (Green puffer)
          Length = 89

 Score = 46.8 bits (106), Expect = 5e-04
 Identities = 20/32 (62%), Positives = 26/32 (81%)
 Frame = +3

Query: 111 KVMKPMLERKRRARINRCLDELKELMVSALQS 206
           KV KP++E+KRRARIN+CLD+LK L+ S   S
Sbjct: 1   KVSKPLMEKKRRARINKCLDQLKSLLESYYSS 32


>UniRef50_A7S155 Cluster: Predicted protein; n=1; Nematostella
           vectensis|Rep: Predicted protein - Nematostella
           vectensis
          Length = 184

 Score = 46.8 bits (106), Expect = 5e-04
 Identities = 27/56 (48%), Positives = 38/56 (67%), Gaps = 6/56 (10%)
 Frame = +3

Query: 111 KVMKPMLERKRRARINRCLDELKELMVSALQSEGENV------AKLEKADILELTV 260
           K  K +LER+RRARIN+ L ELK L++S+L  +   V       +L+KA+IL+LTV
Sbjct: 15  KASKHILERQRRARINQSLAELKNLVLSSLYHDNPEVYMDKSRERLDKAEILDLTV 70


>UniRef50_Q6W4T8 Cluster: Her11; n=3; Danio rerio|Rep: Her11 - Danio
           rerio (Zebrafish) (Brachydanio rerio)
          Length = 274

 Score = 46.4 bits (105), Expect = 6e-04
 Identities = 23/58 (39%), Positives = 37/58 (63%)
 Frame = +3

Query: 87  VSRTYQYRKVMKPMLERKRRARINRCLDELKELMVSALQSEGENVAKLEKADILELTV 260
           +++T   ++ +KP++E+KRR RIN  LD L++L+            KLEKA+IL+L V
Sbjct: 9   MTKTEGIKRRLKPVIEKKRRDRINHNLDALRDLLFKNTADTRLQNPKLEKAEILDLAV 66


>UniRef50_Q504H7 Cluster: Her5 protein; n=3; Danio rerio|Rep: Her5
           protein - Danio rerio (Zebrafish) (Brachydanio rerio)
          Length = 225

 Score = 46.0 bits (104), Expect = 8e-04
 Identities = 22/51 (43%), Positives = 35/51 (68%)
 Frame = +3

Query: 108 RKVMKPMLERKRRARINRCLDELKELMVSALQSEGENVAKLEKADILELTV 260
           R+V KP++E++RR RIN+ L+ L+ L++    +E     K+EKA+ILE  V
Sbjct: 27  RRVPKPLMEKRRRDRINQSLETLRMLLLENTNNEKLKNPKVEKAEILESVV 77


>UniRef50_Q53U31 Cluster: Enhancer of split related protein 1b; n=1;
           Xenopus laevis|Rep: Enhancer of split related protein 1b
           - Xenopus laevis (African clawed frog)
          Length = 154

 Score = 45.6 bits (103), Expect = 0.001
 Identities = 24/50 (48%), Positives = 33/50 (66%)
 Frame = +3

Query: 111 KVMKPMLERKRRARINRCLDELKELMVSALQSEGENVAKLEKADILELTV 260
           K+ KP++E+ RR RIN  +++LK L+      +  NV KLEKADILE  V
Sbjct: 18  KLRKPIVEKMRRDRINNSIEQLKLLLGKEFHEQEPNV-KLEKADILEKAV 66


>UniRef50_Q90Z13 Cluster: Enhancer of split related 2; n=2;
           Xenopus|Rep: Enhancer of split related 2 - Xenopus
           laevis (African clawed frog)
          Length = 183

 Score = 45.2 bits (102), Expect = 0.001
 Identities = 25/55 (45%), Positives = 35/55 (63%)
 Frame = +3

Query: 96  TYQYRKVMKPMLERKRRARINRCLDELKELMVSALQSEGENVAKLEKADILELTV 260
           T Q  K+ KPM+E+ RR RIN  +++L+ L+    Q    + +K EKADILEL V
Sbjct: 40  TKQKTKIRKPMVEKMRRDRINSSINQLRNLLEQEFQLLQPD-SKPEKADILELAV 93


>UniRef50_Q693N2 Cluster: Hairy; n=1; Clogmia albipunctata|Rep:
           Hairy - Clogmia albipunctata (Mothmidge)
          Length = 316

 Score = 43.2 bits (97), Expect = 0.006
 Identities = 29/79 (36%), Positives = 41/79 (51%), Gaps = 2/79 (2%)
 Frame = +3

Query: 222 AKLEKADILELTVXXXXXXXXXXXXXXNPSVD--VDRFRAGFTHAANEVSRCLASIPGVD 395
           +KLEKADILE TV                S    +++F+AGFT  ANEV R      G+D
Sbjct: 6   SKLEKADILEKTVKHLQDLQRQQSVLSQASDPGVINKFKAGFTECANEVGR----FGGID 61

Query: 396 VRLGTQLMTHLGHRLNDMQ 452
             +  +L+ HL + LN ++
Sbjct: 62  PIVKRRLLQHLSNCLNGVR 80


>UniRef50_Q5TA89 Cluster: Transcription factor HES-5; n=11;
           Amniota|Rep: Transcription factor HES-5 - Homo sapiens
           (Human)
          Length = 166

 Score = 43.2 bits (97), Expect = 0.006
 Identities = 22/50 (44%), Positives = 33/50 (66%)
 Frame = +3

Query: 111 KVMKPMLERKRRARINRCLDELKELMVSALQSEGENVAKLEKADILELTV 260
           ++ KP++E+ RR RIN  +++LK L+         N +KLEKADILE+ V
Sbjct: 18  RLRKPVVEKMRRDRINSSIEQLKLLLEQEFARHQPN-SKLEKADILEMAV 66


>UniRef50_UPI0000360D97 Cluster: Transcription factor HES-5 (Hairy
           and enhancer of split 5).; n=2; Takifugu rubripes|Rep:
           Transcription factor HES-5 (Hairy and enhancer of split
           5). - Takifugu rubripes
          Length = 147

 Score = 42.7 bits (96), Expect = 0.007
 Identities = 20/50 (40%), Positives = 35/50 (70%)
 Frame = +3

Query: 111 KVMKPMLERKRRARINRCLDELKELMVSALQSEGENVAKLEKADILELTV 260
           ++ KP++E+ RR RIN  +++LK L+      +  + +K+EKAD+LE+TV
Sbjct: 9   QLRKPLVEKLRRERINSSIEQLKSLLGPEFFKQQPD-SKMEKADVLEMTV 57


>UniRef50_Q4V986 Cluster: Her4.2 protein; n=8; Danio rerio|Rep:
           Her4.2 protein - Danio rerio (Zebrafish) (Brachydanio
           rerio)
          Length = 152

 Score = 42.7 bits (96), Expect = 0.007
 Identities = 21/50 (42%), Positives = 34/50 (68%)
 Frame = +3

Query: 111 KVMKPMLERKRRARINRCLDELKELMVSALQSEGENVAKLEKADILELTV 260
           K+ KPM+E+ RR RIN  +++LK L+      +  + ++ EKADILE+T+
Sbjct: 19  KLRKPMVEKIRRERINSSIEKLKTLLAQEFVKQQPD-SRQEKADILEMTL 67


>UniRef50_Q9PTN9 Cluster: Enhancer of split related epidermal
           protein-6; n=2; Xenopus|Rep: Enhancer of split related
           epidermal protein-6 - Xenopus laevis (African clawed
           frog)
          Length = 144

 Score = 42.3 bits (95), Expect = 0.010
 Identities = 21/47 (44%), Positives = 33/47 (70%)
 Frame = +3

Query: 120 KPMLERKRRARINRCLDELKELMVSALQSEGENVAKLEKADILELTV 260
           KP++E+ RR RIN  +++L+ L+    Q+   + +KLEKADILE+ V
Sbjct: 4   KPVIEKMRRDRINNSIEQLRILLERNFQTHHPH-SKLEKADILEMAV 49


>UniRef50_Q28JA3 Cluster: Novel helix-loop-helix DNA binding domain
           protein; n=2; Xenopus tropicalis|Rep: Novel
           helix-loop-helix DNA binding domain protein - Xenopus
           tropicalis (Western clawed frog) (Silurana tropicalis)
          Length = 155

 Score = 42.3 bits (95), Expect = 0.010
 Identities = 22/51 (43%), Positives = 34/51 (66%)
 Frame = +3

Query: 108 RKVMKPMLERKRRARINRCLDELKELMVSALQSEGENVAKLEKADILELTV 260
           RK+ KP++E+ RR RIN  +++L+ L+    +S     +K EKADILE+ V
Sbjct: 20  RKMRKPVVEKMRRDRINSSIEQLRMLLEKEFESH-HLPSKPEKADILEVAV 69


>UniRef50_Q1L7T5 Cluster: Her4; n=5; Percomorpha|Rep: Her4 - Oryzias
           latipes (Medaka fish) (Japanese ricefish)
          Length = 166

 Score = 42.3 bits (95), Expect = 0.010
 Identities = 22/50 (44%), Positives = 33/50 (66%)
 Frame = +3

Query: 111 KVMKPMLERKRRARINRCLDELKELMVSALQSEGENVAKLEKADILELTV 260
           K+ KPM+E+ RR RIN  +++LK L+      +  + +K EKADILE+ V
Sbjct: 19  KLRKPMVEKLRRDRINTSIEQLKSLLSPEFLRQQPD-SKQEKADILEMAV 67


>UniRef50_A6NFD8 Cluster: Uncharacterized protein ENSP00000343464;
           n=10; Theria|Rep: Uncharacterized protein
           ENSP00000343464 - Homo sapiens (Human)
          Length = 327

 Score = 36.3 bits (80), Expect(2) = 0.015
 Identities = 16/34 (47%), Positives = 24/34 (70%)
 Frame = +3

Query: 114 VMKPMLERKRRARINRCLDELKELMVSALQSEGE 215
           V   ++E++RR RINRCL+EL + +  AL  +GE
Sbjct: 57  VSHKVIEKRRRDRINRCLNELGKTVPMALAKQGE 90



 Score = 24.6 bits (51), Expect(2) = 0.015
 Identities = 14/21 (66%), Positives = 16/21 (76%)
 Frame = +3

Query: 198 LQSEGENVAKLEKADILELTV 260
           LQS G    KLEKA+ILE+TV
Sbjct: 128 LQSSG----KLEKAEILEMTV 144


>UniRef50_Q688C9 Cluster: 213F14-1; n=9; Xenopus|Rep: 213F14-1 -
           Xenopus tropicalis (Western clawed frog) (Silurana
           tropicalis)
          Length = 158

 Score = 41.5 bits (93), Expect = 0.017
 Identities = 22/51 (43%), Positives = 33/51 (64%)
 Frame = +3

Query: 108 RKVMKPMLERKRRARINRCLDELKELMVSALQSEGENVAKLEKADILELTV 260
           RK+ KP++E+ RR RIN  +++L+ L+     S     +K EKADILE+ V
Sbjct: 22  RKMRKPVVEKMRRDRINSSIEQLRMLLEKEFDSH-HLPSKPEKADILEVAV 71


>UniRef50_Q5TGS1 Cluster: Transcription factor HES-3; n=11;
           Eutheria|Rep: Transcription factor HES-3 - Homo sapiens
           (Human)
          Length = 186

 Score = 41.5 bits (93), Expect = 0.017
 Identities = 24/44 (54%), Positives = 30/44 (68%)
 Frame = +3

Query: 129 LERKRRARINRCLDELKELMVSALQSEGENVAKLEKADILELTV 260
           +E+KRRARIN  L++LK L+     S      KLEKADILEL+V
Sbjct: 1   MEKKRRARINVSLEQLKSLL-EKHYSHQIRKRKLEKADILELSV 43


>UniRef50_Q90464 Cluster: HER-2 protein; n=1; Danio rerio|Rep: HER-2
           protein - Danio rerio (Zebrafish) (Brachydanio rerio)
          Length = 108

 Score = 40.7 bits (91), Expect = 0.030
 Identities = 19/40 (47%), Positives = 31/40 (77%)
 Frame = +3

Query: 141 RRARINRCLDELKELMVSALQSEGENVAKLEKADILELTV 260
           RR RIN+C+++LK L+ + +++  +  +KLEKADILE+ V
Sbjct: 2   RRDRINKCIEQLKILLKTEIKA-SQPCSKLEKADILEMAV 40


>UniRef50_UPI0000D9CBA5 Cluster: PREDICTED: similar to basic
           helix-loop-helix domain containing, class B, 3; n=2;
           Eutheria|Rep: PREDICTED: similar to basic
           helix-loop-helix domain containing, class B, 3 - Macaca
           mulatta
          Length = 353

 Score = 40.3 bits (90), Expect = 0.039
 Identities = 21/50 (42%), Positives = 33/50 (66%)
 Frame = +3

Query: 111 KVMKPMLERKRRARINRCLDELKELMVSALQSEGENVAKLEKADILELTV 260
           K+   ++E+KRR RIN C+ +LK+L+   L+     +  LEKA +LELT+
Sbjct: 46  KLPHRLIEKKRRDRINECIAQLKDLLPEHLKL--TTLGHLEKAVVLELTL 93


>UniRef50_Q6GNE9 Cluster: LOC443665 protein; n=4; Xenopus|Rep:
           LOC443665 protein - Xenopus laevis (African clawed frog)
          Length = 409

 Score = 40.3 bits (90), Expect = 0.039
 Identities = 21/50 (42%), Positives = 33/50 (66%)
 Frame = +3

Query: 111 KVMKPMLERKRRARINRCLDELKELMVSALQSEGENVAKLEKADILELTV 260
           K+   ++E+KRR RIN C+ +LK+L+   L+     +  LEKA +LELT+
Sbjct: 96  KLPHRLIEKKRRDRINECIAQLKDLLPEHLKL--TTLGHLEKAVVLELTL 143


>UniRef50_Q2L4U4 Cluster: BHLH protein DEC1b; n=5; Euteleostomi|Rep:
           BHLH protein DEC1b - Oryzias latipes (Medaka fish)
           (Japanese ricefish)
          Length = 428

 Score = 40.3 bits (90), Expect = 0.039
 Identities = 21/50 (42%), Positives = 33/50 (66%)
 Frame = +3

Query: 111 KVMKPMLERKRRARINRCLDELKELMVSALQSEGENVAKLEKADILELTV 260
           K+   ++E+KRR RIN C+ +LK+L+   L+     +  LEKA +LELT+
Sbjct: 48  KLPHRLIEKKRRDRINECIAQLKDLLPEHLKL--TTLGHLEKAVVLELTL 95


>UniRef50_Q99PV5 Cluster: Class B basic helix-loop-helix protein 3;
           n=10; Euteleostomi|Rep: Class B basic helix-loop-helix
           protein 3 - Mus musculus (Mouse)
          Length = 410

 Score = 40.3 bits (90), Expect = 0.039
 Identities = 21/50 (42%), Positives = 33/50 (66%)
 Frame = +3

Query: 111 KVMKPMLERKRRARINRCLDELKELMVSALQSEGENVAKLEKADILELTV 260
           K+   ++E+KRR RIN C+ +LK+L+   L+     +  LEKA +LELT+
Sbjct: 46  KLPHRLIEKKRRDRINECIAQLKDLLPEHLKL--TTLGHLEKAVVLELTL 93


>UniRef50_Q9C0J9 Cluster: Class B basic helix-loop-helix protein 3;
           n=9; Tetrapoda|Rep: Class B basic helix-loop-helix
           protein 3 - Homo sapiens (Human)
          Length = 482

 Score = 40.3 bits (90), Expect = 0.039
 Identities = 21/50 (42%), Positives = 33/50 (66%)
 Frame = +3

Query: 111 KVMKPMLERKRRARINRCLDELKELMVSALQSEGENVAKLEKADILELTV 260
           K+   ++E+KRR RIN C+ +LK+L+   L+     +  LEKA +LELT+
Sbjct: 46  KLPHRLIEKKRRDRINECIAQLKDLLPEHLKL--TTLGHLEKAVVLELTL 93


>UniRef50_O14503 Cluster: Class B basic helix-loop-helix protein 2;
           n=22; Euteleostomi|Rep: Class B basic helix-loop-helix
           protein 2 - Homo sapiens (Human)
          Length = 412

 Score = 40.3 bits (90), Expect = 0.039
 Identities = 21/50 (42%), Positives = 33/50 (66%)
 Frame = +3

Query: 111 KVMKPMLERKRRARINRCLDELKELMVSALQSEGENVAKLEKADILELTV 260
           K+   ++E+KRR RIN C+ +LK+L+   L+     +  LEKA +LELT+
Sbjct: 54  KLPHRLIEKKRRDRINECIAQLKDLLPEHLKL--TTLGHLEKAVVLELTL 101


>UniRef50_Q16SR7 Cluster: Class b basic helix-loop-helix protein;
           n=2; Culicidae|Rep: Class b basic helix-loop-helix
           protein - Aedes aegypti (Yellowfever mosquito)
          Length = 507

 Score = 39.5 bits (88), Expect = 0.068
 Identities = 29/150 (19%), Positives = 65/150 (43%)
 Frame = +3

Query: 6   TYTFTEHTMSTMSYEIAYSLADDGPQPVSRTYQYRKVMKPMLERKRRARINRCLDELKEL 185
           +Y   +   ST +   +   AD  P    +T +   +   ++E++RR R+N CL +L  L
Sbjct: 10  SYCNEQLNFSTTNTNYSEDDADFAPGRRGKTSRQDPLSHRIIEKRRRDRMNSCLADLSRL 69

Query: 186 MVSALQSEGENVAKLEKADILELTVXXXXXXXXXXXXXXNPSVDVDRFRAGFTHAANEVS 365
           +      +G    ++EK +I+E+ +              N     +++R G+     E +
Sbjct: 70  IPQQYMRKGR--GRVEKTEIIEMAIRHLKNLQNQECARENSC--SEQYRVGYHDCLTEAA 125

Query: 366 RCLASIPGVDVRLGTQLMTHLGHRLNDMQR 455
           + +    G +  +  +++ HL    N++ +
Sbjct: 126 KFMLRERGEE--MCYRMVAHLKEHCNEIMK 153


>UniRef50_Q1L7T8 Cluster: Her7; n=1; Oryzias latipes|Rep: Her7 -
           Oryzias latipes (Medaka fish) (Japanese ricefish)
          Length = 201

 Score = 37.9 bits (84), Expect = 0.21
 Identities = 33/111 (29%), Positives = 50/111 (45%)
 Frame = +3

Query: 108 RKVMKPMLERKRRARINRCLDELKELMVSALQSEGENVAKLEKADILELTVXXXXXXXXX 287
           RK++K  +E++RR R+NR L+ L+ +++     +     ++EKA+ILE TV         
Sbjct: 14  RKLLKSQVEKRRRERMNRSLERLRTMLLPE-PHQVTPKHRVEKAEILEHTV----IFLQK 68

Query: 288 XXXXXNPSVDVDRFRAGFTHAANEVSRCLASIPGVDVRLGTQLMTHLGHRL 440
                  S     FR GF+      SR L    G  + LG  L      RL
Sbjct: 69  TTKEQTRSGQKQSFRDGFSTCLRRASRFLGP-QGKGLWLGPALDATFSTRL 118


>UniRef50_Q9VGZ5 Cluster: CG17100-PA; n=4; Sophophora|Rep:
           CG17100-PA - Drosophila melanogaster (Fruit fly)
          Length = 698

 Score = 37.9 bits (84), Expect = 0.21
 Identities = 24/84 (28%), Positives = 44/84 (52%), Gaps = 3/84 (3%)
 Frame = +3

Query: 18  TEHTMSTMSYEIAYSLADDGPQPVSR---TYQYRKVMKPMLERKRRARINRCLDELKELM 188
           TE +++  +   AYS  DD      R   T +   +   ++E++RR R+N CL +L  L+
Sbjct: 31  TESSLNFSTSATAYS-EDDAEYATGRRNKTSRQDPLSHRIIEKRRRDRMNSCLADLSRLI 89

Query: 189 VSALQSEGENVAKLEKADILELTV 260
               Q +G    ++EK +I+E+ +
Sbjct: 90  PPQYQRKGR--GRIEKTEIIEMAI 111


>UniRef50_A7RYX5 Cluster: Predicted protein; n=1; Nematostella
           vectensis|Rep: Predicted protein - Nematostella
           vectensis
          Length = 211

 Score = 37.5 bits (83), Expect = 0.28
 Identities = 24/51 (47%), Positives = 32/51 (62%)
 Frame = +3

Query: 108 RKVMKPMLERKRRARINRCLDELKELMVSALQSEGENVAKLEKADILELTV 260
           +K  K   ER+RR RIN+ L+ELK   ++ L    +NV KLE A ILE +V
Sbjct: 20  QKATKSYAERQRRTRINKSLEELK---LTVLGPSYQNV-KLEHAAILEFSV 66


>UniRef50_P20188 Cluster: Uncharacterized 44.4 kDa protein in
           transposon Tn4556; n=1; Streptomyces fradiae|Rep:
           Uncharacterized 44.4 kDa protein in transposon Tn4556 -
           Streptomyces fradiae
          Length = 395

 Score = 37.5 bits (83), Expect = 0.28
 Identities = 26/64 (40%), Positives = 34/64 (53%), Gaps = 2/64 (3%)
 Frame = +1

Query: 454 ALLPVP-ILRRPVHRARLSPLLPRHLDT*HRRR-QLLRCQFKPVHLWTAQPTLPSPREQQ 627
           A+ PVP  LR+P  R       PRH++  H  R  LLR   +P+HL T  P  P+P+  Q
Sbjct: 211 AVHPVPGQLRQPARR------YPRHINGAHSERGDLLRPLQRPLHLRTRHPHRPAPQPVQ 264

Query: 628 YGDP 639
             DP
Sbjct: 265 LRDP 268


>UniRef50_Q6XLP6 Cluster: Hairy-related 9; n=2; Clupeocephala|Rep:
           Hairy-related 9 - Danio rerio (Zebrafish) (Brachydanio
           rerio)
          Length = 50

 Score = 37.1 bits (82), Expect = 0.36
 Identities = 16/36 (44%), Positives = 23/36 (63%)
 Frame = +3

Query: 78  PQPVSRTYQYRKVMKPMLERKRRARINRCLDELKEL 185
           P       ++RK  KP++E++RRARIN  L +LK L
Sbjct: 15  PDKPKNASEHRKSSKPIMEKRRRARINESLGQLKTL 50


>UniRef50_Q5KHD0 Cluster: Putative uncharacterized protein; n=2;
           Filobasidiella neoformans|Rep: Putative uncharacterized
           protein - Cryptococcus neoformans (Filobasidiella
           neoformans)
          Length = 641

 Score = 37.1 bits (82), Expect = 0.36
 Identities = 22/53 (41%), Positives = 32/53 (60%)
 Frame = +3

Query: 102 QYRKVMKPMLERKRRARINRCLDELKELMVSALQSEGENVAKLEKADILELTV 260
           Q RKV   ++ER+RR +IN  L+EL+  MV +L   G    +  K ++LE TV
Sbjct: 130 QLRKVNHSLIERRRREKINAALNELRR-MVPSLGENGGKGGEF-KLEVLEKTV 180


>UniRef50_Q4SLN8 Cluster: Chromosome 15 SCAF14556, whole genome
            shotgun sequence; n=3; Tetraodontidae|Rep: Chromosome 15
            SCAF14556, whole genome shotgun sequence - Tetraodon
            nigroviridis (Green puffer)
          Length = 2646

 Score = 36.7 bits (81), Expect = 0.48
 Identities = 19/46 (41%), Positives = 25/46 (54%)
 Frame = +3

Query: 81   QPVSRTYQYRKVMKPMLERKRRARINRCLDELKELMVSALQSEGEN 218
            QP+ R  +Y+ V+K ++  K R   N CL E    MVSAL    EN
Sbjct: 2026 QPLERIQKYKVVLKELIRNKARNGQNCCLLEEAYAMVSALPQRSEN 2071


>UniRef50_Q693M9 Cluster: Hairy; n=1; Coboldia fuscipes|Rep: Hairy -
           Coboldia fuscipes
          Length = 253

 Score = 36.7 bits (81), Expect = 0.48
 Identities = 27/85 (31%), Positives = 42/85 (49%), Gaps = 3/85 (3%)
 Frame = +3

Query: 183 LMVSALQSEGENVAKLEKADILELTV---XXXXXXXXXXXXXXNPSVDVDRFRAGFTHAA 353
           L++ A + +    +KLEKADILE TV                 NP V +++F+AG+    
Sbjct: 2   LILDATKKDPARHSKLEKADILEKTVKYLQDLQRQQSIISQAANPKV-LNKFKAGYMECV 60

Query: 354 NEVSRCLASIPGVDVRLGTQLMTHL 428
           N+V R     PG++  +   L+ HL
Sbjct: 61  NQVER----FPGLEPDIRRCLVQHL 81


>UniRef50_Q2H624 Cluster: Putative uncharacterized protein; n=1;
           Chaetomium globosum|Rep: Putative uncharacterized
           protein - Chaetomium globosum (Soil fungus)
          Length = 413

 Score = 36.3 bits (80), Expect = 0.64
 Identities = 22/59 (37%), Positives = 30/59 (50%)
 Frame = +3

Query: 66  ADDGPQPVSRTYQYRKVMKPMLERKRRARINRCLDELKELMVSALQSEGENVAKLEKAD 242
           A  G QP SRT + R V   + ERKRR  +    D+L++LM     S+      L KA+
Sbjct: 277 AHAGAQPYSRTPELR-VSHKLAERKRRTEMKELFDQLRDLMPQERGSKASKWEILTKAE 334


>UniRef50_UPI0000F2B990 Cluster: PREDICTED: hypothetical protein;
           n=1; Monodelphis domestica|Rep: PREDICTED: hypothetical
           protein - Monodelphis domestica
          Length = 172

 Score = 35.9 bits (79), Expect = 0.84
 Identities = 21/50 (42%), Positives = 26/50 (52%), Gaps = 5/50 (10%)
 Frame = +1

Query: 508 PLLPRHLDT*H--RRRQLLRCQFKPVHLWTAQPTLPSP-REQQY--GDPG 642
           P  PR LD+    + R  L C   P H W A P+ P+P R+  Y  GDPG
Sbjct: 105 PETPRALDSPRGAQTRPFLACPLAPTHTWIAPPSPPTPGRKGTYESGDPG 154


>UniRef50_A2AAJ9 Cluster: Obscurin; n=10; Eutheria|Rep: Obscurin - Mus
            musculus (Mouse)
          Length = 8891

 Score = 35.1 bits (77), Expect = 1.5
 Identities = 18/46 (39%), Positives = 25/46 (54%)
 Frame = +3

Query: 81   QPVSRTYQYRKVMKPMLERKRRARINRCLDELKELMVSALQSEGEN 218
            QPV R  +Y+ ++K ++  K R R N  L E    +VSAL    EN
Sbjct: 6771 QPVERVQKYQALLKELIRNKARNRQNCALLEQAYAVVSALPQRAEN 6816


>UniRef50_Q5VST9 Cluster: Obscurin; n=50; Amniota|Rep: Obscurin - Homo
            sapiens (Human)
          Length = 7968

 Score = 35.1 bits (77), Expect = 1.5
 Identities = 18/46 (39%), Positives = 25/46 (54%)
 Frame = +3

Query: 81   QPVSRTYQYRKVMKPMLERKRRARINRCLDELKELMVSALQSEGEN 218
            QPV R  +Y+ ++K ++  K R R N  L E    +VSAL    EN
Sbjct: 5831 QPVERVQRYQALLKELIRNKARNRQNCALLEQAYAVVSALPQRAEN 5876


>UniRef50_UPI00005A480E Cluster: PREDICTED: similar to hairy and
           enhancer of split 6; n=2; Canis lupus familiaris|Rep:
           PREDICTED: similar to hairy and enhancer of split 6 -
           Canis familiaris
          Length = 234

 Score = 34.3 bits (75), Expect = 2.6
 Identities = 20/71 (28%), Positives = 33/71 (46%), Gaps = 2/71 (2%)
 Frame = +3

Query: 222 AKLEKADILELTVXXXXXXXXXXXXXXNP--SVDVDRFRAGFTHAANEVSRCLASIPGVD 395
           AKLE A++LELTV                  +   +RF AG+    +EV   +++   +D
Sbjct: 69  AKLENAEVLELTVRRVQGTLRGRAREREQLQAEASERFAAGYIQCMHEVHTFVSTCQAID 128

Query: 396 VRLGTQLMTHL 428
             +  +L+ HL
Sbjct: 129 ATVAAELLNHL 139


>UniRef50_Q5M8T3 Cluster: HES5 protein; n=3; Eutheria|Rep: HES5
           protein - Homo sapiens (Human)
          Length = 172

 Score = 34.3 bits (75), Expect = 2.6
 Identities = 19/40 (47%), Positives = 25/40 (62%)
 Frame = +3

Query: 141 RRARINRCLDELKELMVSALQSEGENVAKLEKADILELTV 260
           RR RIN  +++LK L+         N +KLEKADILE+ V
Sbjct: 2   RRDRINSSIEQLKLLLEQEFARHQPN-SKLEKADILEMAV 40


>UniRef50_Q6CD58 Cluster: Similarity; n=1; Yarrowia lipolytica|Rep:
           Similarity - Yarrowia lipolytica (Candida lipolytica)
          Length = 493

 Score = 34.3 bits (75), Expect = 2.6
 Identities = 22/54 (40%), Positives = 32/54 (59%), Gaps = 3/54 (5%)
 Frame = +3

Query: 108 RKVMKPMLERKRRARINRCLDELKELMVSALQS---EGENVAKLEKADILELTV 260
           RK     +ER+RR+++N   D LK+L+ +  QS   EG + A L K  IL+ TV
Sbjct: 294 RKTAHSAIERRRRSKMNEEFDSLKQLVPACRQSIAAEGGD-AGLHKLTILQATV 346


>UniRef50_UPI0000DB76C3 Cluster: PREDICTED: similar to CG17100-PA;
           n=1; Apis mellifera|Rep: PREDICTED: similar to
           CG17100-PA - Apis mellifera
          Length = 400

 Score = 33.9 bits (74), Expect = 3.4
 Identities = 14/45 (31%), Positives = 29/45 (64%)
 Frame = +3

Query: 126 MLERKRRARINRCLDELKELMVSALQSEGENVAKLEKADILELTV 260
           ++E++RR R+N CL +L  L+ +    +G    ++EK +I+E+ +
Sbjct: 73  IIEKRRRDRMNNCLADLSRLIPAEYLKKGR--GRVEKTEIIEMAI 115


>UniRef50_Q58EP4 Cluster: LOC572412 protein; n=2; Danio rerio|Rep:
           LOC572412 protein - Danio rerio (Zebrafish) (Brachydanio
           rerio)
          Length = 1095

 Score = 33.9 bits (74), Expect = 3.4
 Identities = 17/46 (36%), Positives = 24/46 (52%)
 Frame = +3

Query: 81  QPVSRTYQYRKVMKPMLERKRRARINRCLDELKELMVSALQSEGEN 218
           +P  R  +YR ++K ++  K R   N CL E    MVS+L    EN
Sbjct: 347 RPPERIQKYRALLKELIRNKARNGQNCCLLEQAYAMVSSLSQRSEN 392


>UniRef50_A7MB72 Cluster: MGC166429 protein; n=4; Tetrapoda|Rep:
           MGC166429 protein - Bos taurus (Bovine)
          Length = 813

 Score = 33.9 bits (74), Expect = 3.4
 Identities = 18/46 (39%), Positives = 24/46 (52%)
 Frame = +3

Query: 81  QPVSRTYQYRKVMKPMLERKRRARINRCLDELKELMVSALQSEGEN 218
           QPV R  QY+ ++K ++  K R   N  L E    +VSAL    EN
Sbjct: 37  QPVERVQQYQALLKELIRNKARNGQNCALLEQAYAVVSALPQRAEN 82


>UniRef50_Q4S869 Cluster: Chromosome 5 SCAF14709, whole genome
           shotgun sequence; n=2; Tetraodon nigroviridis|Rep:
           Chromosome 5 SCAF14709, whole genome shotgun sequence -
           Tetraodon nigroviridis (Green puffer)
          Length = 492

 Score = 33.5 bits (73), Expect = 4.5
 Identities = 16/30 (53%), Positives = 17/30 (56%)
 Frame = +2

Query: 257 SSSPSQTKAPTTLVTEPKCGRGSLPSWIHA 346
           SSSP      T LV  P CGR +L SW HA
Sbjct: 441 SSSPEDRVLQTALVLLPLCGRDALLSWHHA 470


>UniRef50_A1SDB9 Cluster: Putative uncharacterized protein; n=1;
           Nocardioides sp. JS614|Rep: Putative uncharacterized
           protein - Nocardioides sp. (strain BAA-499 / JS614)
          Length = 454

 Score = 33.5 bits (73), Expect = 4.5
 Identities = 19/55 (34%), Positives = 35/55 (63%), Gaps = 5/55 (9%)
 Frame = +3

Query: 72  DGPQPVSRTYQ-YRKVMK--PMLERKRRARINRCL--DELKELMVSALQSEGENV 221
           DGPQPVSR    Y  +++  P  E++  A++ R +  + L++++ +ALQS G+ +
Sbjct: 6   DGPQPVSRAESLYTALVRRNPETEQEMPAQVRRSIAPNGLRQVLANALQSSGDQL 60


>UniRef50_Q695L3 Cluster: Obscurin-MLCK; n=5; Clupeocephala|Rep:
           Obscurin-MLCK - Danio rerio (Zebrafish) (Brachydanio
           rerio)
          Length = 2009

 Score = 33.1 bits (72), Expect = 5.9
 Identities = 18/50 (36%), Positives = 27/50 (54%)
 Frame = +3

Query: 81  QPVSRTYQYRKVMKPMLERKRRARINRCLDELKELMVSALQSEGENVAKL 230
           +P+ R   Y+ V+K M+  K ++  N CL E    MVS+L    EN+  L
Sbjct: 134 RPMERIETYKTVLKEMIRNKAKSGQNCCLLEDAFAMVSSLPWRAENLHHL 183


>UniRef50_Q92XL8 Cluster: Putative uncharacterized protein; n=1;
           Sinorhizobium meliloti|Rep: Putative uncharacterized
           protein - Rhizobium meliloti (Sinorhizobium meliloti)
          Length = 126

 Score = 32.7 bits (71), Expect = 7.8
 Identities = 14/23 (60%), Positives = 19/23 (82%)
 Frame = +1

Query: 451 SALLPVPILRRPVHRARLSPLLP 519
           +A+LP P LRRP++RAR  P+LP
Sbjct: 15  TAILPTP-LRRPIYRARQHPMLP 36


>UniRef50_A7RQW2 Cluster: Predicted protein; n=2; Nematostella
           vectensis|Rep: Predicted protein - Nematostella
           vectensis
          Length = 212

 Score = 32.7 bits (71), Expect = 7.8
 Identities = 18/57 (31%), Positives = 30/57 (52%)
 Frame = +3

Query: 90  SRTYQYRKVMKPMLERKRRARINRCLDELKELMVSALQSEGENVAKLEKADILELTV 260
           S + Q R+    + E+KRR  I +  D+L+ ++ +   S      KL KA IL+ T+
Sbjct: 37  SSSKQNRRFAHSVAEQKRRDAIKKGYDDLQSIVPTCQHSTSAGSPKLSKAIILQRTI 93


  Database: uniref50
    Posted date:  Oct 5, 2007 11:19 AM
  Number of letters in database: 575,637,011
  Number of sequences in database:  1,657,284
  
Lambda     K      H
   0.318    0.134    0.401 

Gapped
Lambda     K      H
   0.279   0.0580    0.190 


Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 656,518,305
Number of Sequences: 1657284
Number of extensions: 13112385
Number of successful extensions: 39532
Number of sequences better than 10.0: 141
Number of HSP's better than 10.0 without gapping: 37849
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 39437
length of database: 575,637,011
effective HSP length: 98
effective length of database: 413,223,179
effective search space used: 48760335122
frameshift window, decay const: 40,  0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)

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