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Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= I10A02NGRL0003_E06
         (652 letters)

Database: human 
           237,096 sequences; 76,859,062 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

L19314-1|AAA65220.1|  280|Homo sapiens HRY protein.                    89   2e-17
CR541843-1|CAG46641.1|  280|Homo sapiens HES1 protein.                 89   2e-17
BC039152-1|AAH39152.1|  277|Homo sapiens HES1 protein protein.         89   2e-17
AK000415-1|BAA91149.1|  280|Homo sapiens protein ( Homo sapiens ...    89   2e-17
AF264785-1|AAF73060.1|  280|Homo sapiens hairy protein.                89   2e-17
BC012351-1|AAH12351.1|  221|Homo sapiens hairy and enhancer of s...    81   4e-15
AL645608-10|CAI15572.1|  221|Homo sapiens hairy and enhancer of ...    81   4e-15
AB048791-1|BAB13510.1|  221|Homo sapiens bHLH factor Hes4 protein.     81   4e-15
BC142687-1|AAI42688.1|  173|Homo sapiens HES2 protein protein.         75   3e-13
BC132698-1|AAI32699.1|  173|Homo sapiens hairy and enhancer of s...    75   3e-13
AL031848-4|CAB46198.1|  173|Homo sapiens hairy and enhancer of s...    75   3e-13
BC007939-1|AAH07939.1|  224|Homo sapiens hairy and enhancer of s...    62   2e-09
AC016757-5|AAY24337.1|  224|Homo sapiens unknown protein.              62   2e-09
AB035179-1|BAA96082.1|  224|Homo sapiens HES6 protein.                 62   2e-09
AF260237-1|AAK51634.1|  222|Homo sapiens hairy/enhancer of split...    59   1e-08
BT020068-1|AAV38871.1|  337|Homo sapiens hairy/enhancer-of-split...    59   2e-08
BT020067-1|AAV38870.1|  337|Homo sapiens hairy/enhancer-of-split...    59   2e-08
BC007707-1|AAH07707.1|  337|Homo sapiens hairy/enhancer-of-split...    59   2e-08
AL078594-2|CAI20068.1|  291|Homo sapiens hairy/enhancer-of-split...    59   2e-08
AL078594-1|CAB87581.1|  337|Homo sapiens hairy/enhancer-of-split...    59   2e-08
AJ249545-1|CAB56839.1|  337|Homo sapiens basic-helix-loop-helix ...    59   2e-08
AF311884-1|AAG31157.1|  337|Homo sapiens hairy-related transcrip...    59   2e-08
AF237949-1|AAF44781.1|  337|Homo sapiens GRIDLOCK protein.             59   2e-08
AF232238-1|AAF37296.1|  337|Homo sapiens HES-related repressor p...    59   2e-08
AF173901-1|AAF20173.1|  337|Homo sapiens basic helix-loop-helix ...    59   2e-08
AB044755-1|BAA96781.1|  337|Homo sapiens basic-helix-loop-helix ...    59   2e-08
BT020065-1|AAV38868.1|  304|Homo sapiens hairy/enhancer-of-split...    57   5e-08
BC001873-1|AAH01873.1|  304|Homo sapiens hairy/enhancer-of-split...    57   5e-08
AJ272214-1|CAB75715.1|  304|Homo sapiens HEY1 protein protein.         57   5e-08
AF311883-1|AAG31156.1|  304|Homo sapiens hairy-related transcrip...    57   5e-08
AF254637-1|AAL06278.1|  304|Homo sapiens basic helix-loop-helix ...    57   5e-08
AF232239-1|AAF37297.1|  304|Homo sapiens HES-related repressor p...    57   5e-08
AF176422-1|AAD51749.1|  304|Homo sapiens cardiovascular helix-lo...    57   5e-08
AF151522-1|AAD38967.1|  304|Homo sapiens hairy and enhancer of s...    57   5e-08
BC006087-1|AAH06087.1|  328|Homo sapiens hairy/enhancer-of-split...    54   3e-07
AJ272215-1|CAB75716.1|  328|Homo sapiens HEYL protein protein.         54   3e-07
AF311885-1|AAG31158.1|  328|Homo sapiens hairy-related transcrip...    54   3e-07
AL035404-1|CAI19572.1|  328|Homo sapiens hairy/enhancer-of-split...    54   4e-07
AK092437-1|BAC03890.1|  308|Homo sapiens protein ( Homo sapiens ...    54   4e-07
AK075040-1|BAC11368.1|  214|Homo sapiens protein ( Homo sapiens ...    51   4e-06
AB049064-1|BAB39525.1|  225|Homo sapiens bHLH factor Hes7 protein.     51   4e-06
DQ272660-1|ABB83829.1|  166|Homo sapiens HES5 protein.                 44   6e-04
AL031847-3|CAI19439.1|  180|Homo sapiens hairy and enhancer of s...    42   0.003
BC012091-1|AAH12091.1|   76|Homo sapiens HES2 protein protein.         41   0.003
AL031848-5|CAB46199.1|   76|Homo sapiens hairy and enhancer of s...    41   0.003
EF015896-1|ABM64207.1|  482|Homo sapiens basic helix-loop-helix ...    40   0.006
EF015895-1|ABM64206.1|  412|Homo sapiens basic helix-loop-helix ...    40   0.006
CR456921-1|CAG33202.1|  412|Homo sapiens BHLHB2 protein.               40   0.006
BC082238-1|AAH82238.1|  412|Homo sapiens basic helix-loop-helix ...    40   0.006
BC025968-1|AAH25968.1|  482|Homo sapiens basic helix-loop-helix ...    40   0.006
AY665467-1|AAV54602.1|  482|Homo sapiens basic helix-loop-helix ...    40   0.006
AF353635-1|AAK49525.1|  409|Homo sapiens bHLH transcription fact...    40   0.006
AB044088-1|BAB21502.1|  482|Homo sapiens bHLH protein DEC2 protein.    40   0.006
AB043885-1|BAB18565.1|  412|Homo sapiens bHLH transcriptional fa...    40   0.006
AB004066-1|BAA21720.1|  412|Homo sapiens DEC1 protein.                 40   0.006
AL670729-4|CAH71670.2| 2582|Homo sapiens obscurin, cytoskeletal ...    35   0.22 
AL670729-3|CAH71673.1| 6620|Homo sapiens obscurin, cytoskeletal ...    35   0.22 
AL359510-13|CAI15072.1| 6620|Homo sapiens obscurin, cytoskeletal...    35   0.22 
AL353593-4|CAM27610.1| 2582|Homo sapiens obscurin, cytoskeletal ...    35   0.22 
AL353593-3|CAI19285.1| 6620|Homo sapiens obscurin, cytoskeletal ...    35   0.22 
AJ314908-1|CAC85755.1| 1020|Homo sapiens obscurin protein.             35   0.22 
AJ002535-1|CAC44768.1| 6620|Homo sapiens obscurin protein.             35   0.22 
AB046859-1|BAB13465.2| 2584|Homo sapiens KIAA1639 protein protein.     35   0.22 
BC087840-1|AAH87840.1|  172|Homo sapiens HES5 protein protein.         34   0.38 
BC032586-1|AAH32586.1|  363|Homo sapiens MXD3 protein protein.         30   8.2  
BC000745-1|AAH00745.1|  206|Homo sapiens MAX dimerization protei...    30   8.2  
AK222579-1|BAD96299.1|  206|Homo sapiens MAX dimerization protei...    30   8.2  
AK057034-1|BAB71352.1|  193|Homo sapiens protein ( Homo sapiens ...    30   8.2  
AF114834-1|AAP97233.1|  206|Homo sapiens Myx protein.                  30   8.2  

>L19314-1|AAA65220.1|  280|Homo sapiens HRY protein.
          Length = 280

 Score = 88.6 bits (210), Expect = 2e-17
 Identities = 47/122 (38%), Positives = 73/122 (59%), Gaps = 3/122 (2%)
 Frame = +3

Query: 78  PQPVSRTYQYRKVMKPMLERKRRARINRCLDELKELMVSALQSEGENVAKLEKADILELT 257
           P       ++RK  KP++E++RRARIN  L +LK L++ AL+ +    +KLEKADILE+T
Sbjct: 25  PDKPKTASEHRKSSKPIMEKRRRARINESLSQLKTLILDALKKDSSRHSKLEKADILEMT 84

Query: 258 V---XXXXXXXXXXXXXXNPSVDVDRFRAGFTHAANEVSRCLASIPGVDVRLGTQLMTHL 428
           V                 +PSV + ++RAGF+   NEV+R L++  GV+  + T+L+ HL
Sbjct: 85  VKHLRNLQRAQMTAALSTDPSV-LGKYRAGFSECMNEVTRFLSTCEGVNTEVRTRLLGHL 143

Query: 429 GH 434
            +
Sbjct: 144 AN 145


>CR541843-1|CAG46641.1|  280|Homo sapiens HES1 protein.
          Length = 280

 Score = 88.6 bits (210), Expect = 2e-17
 Identities = 47/122 (38%), Positives = 73/122 (59%), Gaps = 3/122 (2%)
 Frame = +3

Query: 78  PQPVSRTYQYRKVMKPMLERKRRARINRCLDELKELMVSALQSEGENVAKLEKADILELT 257
           P       ++RK  KP++E++RRARIN  L +LK L++ AL+ +    +KLEKADILE+T
Sbjct: 25  PDKPKTASEHRKSSKPIMEKRRRARINESLSQLKTLILDALKKDSSRHSKLEKADILEMT 84

Query: 258 V---XXXXXXXXXXXXXXNPSVDVDRFRAGFTHAANEVSRCLASIPGVDVRLGTQLMTHL 428
           V                 +PSV + ++RAGF+   NEV+R L++  GV+  + T+L+ HL
Sbjct: 85  VKHLRNLQRAQMTAALSTDPSV-LGKYRAGFSECMNEVTRFLSTCEGVNTEVRTRLLGHL 143

Query: 429 GH 434
            +
Sbjct: 144 AN 145


>BC039152-1|AAH39152.1|  277|Homo sapiens HES1 protein protein.
          Length = 277

 Score = 88.6 bits (210), Expect = 2e-17
 Identities = 47/122 (38%), Positives = 73/122 (59%), Gaps = 3/122 (2%)
 Frame = +3

Query: 78  PQPVSRTYQYRKVMKPMLERKRRARINRCLDELKELMVSALQSEGENVAKLEKADILELT 257
           P       ++RK  KP++E++RRARIN  L +LK L++ AL+ +    +KLEKADILE+T
Sbjct: 22  PDKPKTASEHRKSSKPIMEKRRRARINESLSQLKTLILDALKKDSSRHSKLEKADILEMT 81

Query: 258 V---XXXXXXXXXXXXXXNPSVDVDRFRAGFTHAANEVSRCLASIPGVDVRLGTQLMTHL 428
           V                 +PSV + ++RAGF+   NEV+R L++  GV+  + T+L+ HL
Sbjct: 82  VKHLRNLQRAQMTAALSTDPSV-LGKYRAGFSECMNEVTRFLSTCEGVNTEVRTRLLGHL 140

Query: 429 GH 434
            +
Sbjct: 141 AN 142


>AK000415-1|BAA91149.1|  280|Homo sapiens protein ( Homo sapiens
           cDNA FLJ20408 fis, clone KAT01678. ).
          Length = 280

 Score = 88.6 bits (210), Expect = 2e-17
 Identities = 47/122 (38%), Positives = 73/122 (59%), Gaps = 3/122 (2%)
 Frame = +3

Query: 78  PQPVSRTYQYRKVMKPMLERKRRARINRCLDELKELMVSALQSEGENVAKLEKADILELT 257
           P       ++RK  KP++E++RRARIN  L +LK L++ AL+ +    +KLEKADILE+T
Sbjct: 25  PDKPKTASEHRKSSKPIMEKRRRARINESLSQLKTLILDALKKDSSRHSKLEKADILEMT 84

Query: 258 V---XXXXXXXXXXXXXXNPSVDVDRFRAGFTHAANEVSRCLASIPGVDVRLGTQLMTHL 428
           V                 +PSV + ++RAGF+   NEV+R L++  GV+  + T+L+ HL
Sbjct: 85  VKHLRNLQRAQMTAALSTDPSV-LGKYRAGFSECMNEVTRFLSTCEGVNTEVRTRLLGHL 143

Query: 429 GH 434
            +
Sbjct: 144 AN 145


>AF264785-1|AAF73060.1|  280|Homo sapiens hairy protein.
          Length = 280

 Score = 88.6 bits (210), Expect = 2e-17
 Identities = 47/122 (38%), Positives = 73/122 (59%), Gaps = 3/122 (2%)
 Frame = +3

Query: 78  PQPVSRTYQYRKVMKPMLERKRRARINRCLDELKELMVSALQSEGENVAKLEKADILELT 257
           P       ++RK  KP++E++RRARIN  L +LK L++ AL+ +    +KLEKADILE+T
Sbjct: 25  PDKPKTASEHRKSSKPIMEKRRRARINESLSQLKTLILDALKKDSSRHSKLEKADILEMT 84

Query: 258 V---XXXXXXXXXXXXXXNPSVDVDRFRAGFTHAANEVSRCLASIPGVDVRLGTQLMTHL 428
           V                 +PSV + ++RAGF+   NEV+R L++  GV+  + T+L+ HL
Sbjct: 85  VKHLRNLQRAQMTAALSTDPSV-LGKYRAGFSECMNEVTRFLSTCEGVNTEVRTRLLGHL 143

Query: 429 GH 434
            +
Sbjct: 144 AN 145


>BC012351-1|AAH12351.1|  221|Homo sapiens hairy and enhancer of
           split 4 (Drosophila) protein.
          Length = 221

 Score = 80.6 bits (190), Expect = 4e-15
 Identities = 46/119 (38%), Positives = 69/119 (57%), Gaps = 3/119 (2%)
 Frame = +3

Query: 102 QYRKVMKPMLERKRRARINRCLDELKELMVSALQSEGENVAKLEKADILELTV---XXXX 272
           ++RK  KP++E++RRARIN  L +LK L++ AL+ E    +KLEKADILE+TV       
Sbjct: 33  EHRKSSKPVMEKRRRARINESLAQLKTLILDALRKESSRHSKLEKADILEMTVRHLRSLR 92

Query: 273 XXXXXXXXXXNPSVDVDRFRAGFTHAANEVSRCLASIPGVDVRLGTQLMTHLGHRLNDM 449
                     +P+V + ++RAGF     EV+R LA   GV   + ++L+ HL   L  +
Sbjct: 93  RVQVTAALSADPAV-LGKYRAGFHECLAEVNRFLAGCEGVPADVRSRLLGHLAACLRQL 150


>AL645608-10|CAI15572.1|  221|Homo sapiens hairy and enhancer of
           split 4 (Drosophila) protein.
          Length = 221

 Score = 80.6 bits (190), Expect = 4e-15
 Identities = 46/119 (38%), Positives = 69/119 (57%), Gaps = 3/119 (2%)
 Frame = +3

Query: 102 QYRKVMKPMLERKRRARINRCLDELKELMVSALQSEGENVAKLEKADILELTV---XXXX 272
           ++RK  KP++E++RRARIN  L +LK L++ AL+ E    +KLEKADILE+TV       
Sbjct: 33  EHRKSSKPVMEKRRRARINESLAQLKTLILDALRKESSRHSKLEKADILEMTVRHLRSLR 92

Query: 273 XXXXXXXXXXNPSVDVDRFRAGFTHAANEVSRCLASIPGVDVRLGTQLMTHLGHRLNDM 449
                     +P+V + ++RAGF     EV+R LA   GV   + ++L+ HL   L  +
Sbjct: 93  RVQVTAALSADPAV-LGKYRAGFHECLAEVNRFLAGCEGVPADVRSRLLGHLAACLRQL 150


>AB048791-1|BAB13510.1|  221|Homo sapiens bHLH factor Hes4 protein.
          Length = 221

 Score = 80.6 bits (190), Expect = 4e-15
 Identities = 46/119 (38%), Positives = 69/119 (57%), Gaps = 3/119 (2%)
 Frame = +3

Query: 102 QYRKVMKPMLERKRRARINRCLDELKELMVSALQSEGENVAKLEKADILELTV---XXXX 272
           ++RK  KP++E++RRARIN  L +LK L++ AL+ E    +KLEKADILE+TV       
Sbjct: 33  EHRKSSKPVMEKRRRARINESLAQLKTLILDALRKESSRHSKLEKADILEMTVRHLRSLR 92

Query: 273 XXXXXXXXXXNPSVDVDRFRAGFTHAANEVSRCLASIPGVDVRLGTQLMTHLGHRLNDM 449
                     +P+V + ++RAGF     EV+R LA   GV   + ++L+ HL   L  +
Sbjct: 93  RVQVTAALSADPAV-LGKYRAGFHECLAEVNRFLAGCEGVPADVRSRLLGHLAACLRQL 150


>BC142687-1|AAI42688.1|  173|Homo sapiens HES2 protein protein.
          Length = 173

 Score = 74.5 bits (175), Expect = 3e-13
 Identities = 40/120 (33%), Positives = 65/120 (54%)
 Frame = +3

Query: 78  PQPVSRTYQYRKVMKPMLERKRRARINRCLDELKELMVSALQSEGENVAKLEKADILELT 257
           P+      + RK +KP+LE++RRARIN+ L +LK L++  L  E  N +KLEKAD+LE+T
Sbjct: 4   PRRAGDAAELRKSLKPLLEKRRRARINQSLSQLKGLILPLLGRENSNCSKLEKADVLEMT 63

Query: 258 VXXXXXXXXXXXXXXNPSVDVDRFRAGFTHAANEVSRCLASIPGVDVRLGTQLMTHLGHR 437
           V               P +  D +R G++     ++R L +   ++  +  +L+ HL  R
Sbjct: 64  VRFLQELPASSWPTAAP-LPCDSYREGYSACVARLARVLPACRVLEPAVSARLLEHLWRR 122


>BC132698-1|AAI32699.1|  173|Homo sapiens hairy and enhancer of
           split 2 (Drosophila) protein.
          Length = 173

 Score = 74.5 bits (175), Expect = 3e-13
 Identities = 40/120 (33%), Positives = 65/120 (54%)
 Frame = +3

Query: 78  PQPVSRTYQYRKVMKPMLERKRRARINRCLDELKELMVSALQSEGENVAKLEKADILELT 257
           P+      + RK +KP+LE++RRARIN+ L +LK L++  L  E  N +KLEKAD+LE+T
Sbjct: 4   PRRAGDAAELRKSLKPLLEKRRRARINQSLSQLKGLILPLLGRENSNCSKLEKADVLEMT 63

Query: 258 VXXXXXXXXXXXXXXNPSVDVDRFRAGFTHAANEVSRCLASIPGVDVRLGTQLMTHLGHR 437
           V               P +  D +R G++     ++R L +   ++  +  +L+ HL  R
Sbjct: 64  VRFLQELPASSWPTAAP-LPCDSYREGYSACVARLARVLPACRVLEPAVSARLLEHLWRR 122


>AL031848-4|CAB46198.1|  173|Homo sapiens hairy and enhancer of
           split 2 (Drosophila) protein.
          Length = 173

 Score = 74.5 bits (175), Expect = 3e-13
 Identities = 40/120 (33%), Positives = 65/120 (54%)
 Frame = +3

Query: 78  PQPVSRTYQYRKVMKPMLERKRRARINRCLDELKELMVSALQSEGENVAKLEKADILELT 257
           P+      + RK +KP+LE++RRARIN+ L +LK L++  L  E  N +KLEKAD+LE+T
Sbjct: 4   PRRAGDAAELRKSLKPLLEKRRRARINQSLSQLKGLILPLLGRENSNCSKLEKADVLEMT 63

Query: 258 VXXXXXXXXXXXXXXNPSVDVDRFRAGFTHAANEVSRCLASIPGVDVRLGTQLMTHLGHR 437
           V               P +  D +R G++     ++R L +   ++  +  +L+ HL  R
Sbjct: 64  VRFLQELPASSWPTAAP-LPCDSYREGYSACVARLARVLPACRVLEPAVSARLLEHLWRR 122


>BC007939-1|AAH07939.1|  224|Homo sapiens hairy and enhancer of
           split 6 (Drosophila) protein.
          Length = 224

 Score = 61.7 bits (143), Expect = 2e-09
 Identities = 38/109 (34%), Positives = 56/109 (51%), Gaps = 2/109 (1%)
 Frame = +3

Query: 108 RKVMKPMLERKRRARINRCLDELKELMVSALQSEGENVAKLEKADILELTVXXXXXXXXX 287
           RK  KP++E+KRRARIN  L EL+ L+  A     E  AKLE A++LELTV         
Sbjct: 26  RKARKPLVEKKRRARINESLQELRLLLAGA-----EVQAKLENAEVLELTVRRVQGVLRG 80

Query: 288 XXXXXN--PSVDVDRFRAGFTHAANEVSRCLASIPGVDVRLGTQLMTHL 428
                    +   +RF AG+    +EV   +++   +D  +  +L+ HL
Sbjct: 81  RAREREQLQAEASERFAAGYIQCMHEVHTFVSTCQAIDATVAAELLNHL 129


>AC016757-5|AAY24337.1|  224|Homo sapiens unknown protein.
          Length = 224

 Score = 61.7 bits (143), Expect = 2e-09
 Identities = 38/109 (34%), Positives = 56/109 (51%), Gaps = 2/109 (1%)
 Frame = +3

Query: 108 RKVMKPMLERKRRARINRCLDELKELMVSALQSEGENVAKLEKADILELTVXXXXXXXXX 287
           RK  KP++E+KRRARIN  L EL+ L+  A     E  AKLE A++LELTV         
Sbjct: 26  RKARKPLVEKKRRARINESLQELRLLLAGA-----EVQAKLENAEVLELTVRRVQGVLRG 80

Query: 288 XXXXXN--PSVDVDRFRAGFTHAANEVSRCLASIPGVDVRLGTQLMTHL 428
                    +   +RF AG+    +EV   +++   +D  +  +L+ HL
Sbjct: 81  RAREREQLQAEASERFAAGYIQCMHEVHTFVSTCQAIDATVAAELLNHL 129


>AB035179-1|BAA96082.1|  224|Homo sapiens HES6 protein.
          Length = 224

 Score = 61.7 bits (143), Expect = 2e-09
 Identities = 38/109 (34%), Positives = 56/109 (51%), Gaps = 2/109 (1%)
 Frame = +3

Query: 108 RKVMKPMLERKRRARINRCLDELKELMVSALQSEGENVAKLEKADILELTVXXXXXXXXX 287
           RK  KP++E+KRRARIN  L EL+ L+  A     E  AKLE A++LELTV         
Sbjct: 26  RKARKPLVEKKRRARINESLQELRLLLAGA-----EVQAKLENAEVLELTVRRVQGVLRG 80

Query: 288 XXXXXN--PSVDVDRFRAGFTHAANEVSRCLASIPGVDVRLGTQLMTHL 428
                    +   +RF AG+    +EV   +++   +D  +  +L+ HL
Sbjct: 81  RAREREQLQAEASERFAAGYIQCMHEVHTFVSTCQAIDATVAAELLNHL 129


>AF260237-1|AAK51634.1|  222|Homo sapiens hairy/enhancer of split 6
           protein.
          Length = 222

 Score = 59.3 bits (137), Expect = 1e-08
 Identities = 37/109 (33%), Positives = 55/109 (50%), Gaps = 2/109 (1%)
 Frame = +3

Query: 108 RKVMKPMLERKRRARINRCLDELKELMVSALQSEGENVAKLEKADILELTVXXXXXXXXX 287
           RK  KP++E+KRRARIN  L EL+ L+  A        AKLE A++LELTV         
Sbjct: 26  RKARKPLVEKKRRARINESLQELRLLLAGA-------EAKLENAEVLELTVRRVQGVLRG 78

Query: 288 XXXXXN--PSVDVDRFRAGFTHAANEVSRCLASIPGVDVRLGTQLMTHL 428
                    +   +RF AG+    +EV   +++   +D  +  +L+ HL
Sbjct: 79  RAREREQLQAEASERFAAGYIQCMHEVHTFVSTCQAIDATVAAELLNHL 127


>BT020068-1|AAV38871.1|  337|Homo sapiens hairy/enhancer-of-split
           related with YRPW motif 2 protein.
          Length = 337

 Score = 58.8 bits (136), Expect = 2e-08
 Identities = 38/111 (34%), Positives = 61/111 (54%), Gaps = 4/111 (3%)
 Frame = +3

Query: 108 RKVMKPMLERKRRARINRCLDELKELMVSALQSEGENVAKLEKADILELTV--XXXXXXX 281
           RK  + ++E++RR RIN  L EL+ L+ +A + +G   AKLEKA+IL++TV         
Sbjct: 49  RKKRRGIIEKRRRDRINNSLSELRRLVPTAFEKQGS--AKLEKAEILQMTVDHLKMLQAT 106

Query: 282 XXXXXXXNPSVDVDRFRAGFTHAANEVSRCLASIPGVDVR--LGTQLMTHL 428
                    ++ +D    GF     EV+R L+S+ G+D    L  +L++HL
Sbjct: 107 GGKGYFDAHALAMDFMSIGFRECLTEVARYLSSVEGLDSSDPLRVRLVSHL 157


>BT020067-1|AAV38870.1|  337|Homo sapiens hairy/enhancer-of-split
           related with YRPW motif 2 protein.
          Length = 337

 Score = 58.8 bits (136), Expect = 2e-08
 Identities = 38/111 (34%), Positives = 61/111 (54%), Gaps = 4/111 (3%)
 Frame = +3

Query: 108 RKVMKPMLERKRRARINRCLDELKELMVSALQSEGENVAKLEKADILELTV--XXXXXXX 281
           RK  + ++E++RR RIN  L EL+ L+ +A + +G   AKLEKA+IL++TV         
Sbjct: 49  RKKRRGIIEKRRRDRINNSLSELRRLVPTAFEKQGS--AKLEKAEILQMTVDHLKMLQAT 106

Query: 282 XXXXXXXNPSVDVDRFRAGFTHAANEVSRCLASIPGVDVR--LGTQLMTHL 428
                    ++ +D    GF     EV+R L+S+ G+D    L  +L++HL
Sbjct: 107 GGKGYFDAHALAMDFMSIGFRECLTEVARYLSSVEGLDSSDPLRVRLVSHL 157


>BC007707-1|AAH07707.1|  337|Homo sapiens hairy/enhancer-of-split
           related with YRPW motif 2 protein.
          Length = 337

 Score = 58.8 bits (136), Expect = 2e-08
 Identities = 38/111 (34%), Positives = 61/111 (54%), Gaps = 4/111 (3%)
 Frame = +3

Query: 108 RKVMKPMLERKRRARINRCLDELKELMVSALQSEGENVAKLEKADILELTV--XXXXXXX 281
           RK  + ++E++RR RIN  L EL+ L+ +A + +G   AKLEKA+IL++TV         
Sbjct: 49  RKKRRGIIEKRRRDRINNSLSELRRLVPTAFEKQGS--AKLEKAEILQMTVDHLKMLQAT 106

Query: 282 XXXXXXXNPSVDVDRFRAGFTHAANEVSRCLASIPGVDVR--LGTQLMTHL 428
                    ++ +D    GF     EV+R L+S+ G+D    L  +L++HL
Sbjct: 107 GGKGYFDAHALAMDFMSIGFRECLTEVARYLSSVEGLDSSDPLRVRLVSHL 157


>AL078594-2|CAI20068.1|  291|Homo sapiens hairy/enhancer-of-split
           related with YRPW motif 2 protein.
          Length = 291

 Score = 58.8 bits (136), Expect = 2e-08
 Identities = 38/111 (34%), Positives = 61/111 (54%), Gaps = 4/111 (3%)
 Frame = +3

Query: 108 RKVMKPMLERKRRARINRCLDELKELMVSALQSEGENVAKLEKADILELTV--XXXXXXX 281
           RK  + ++E++RR RIN  L EL+ L+ +A + +G   AKLEKA+IL++TV         
Sbjct: 3   RKKRRGIIEKRRRDRINNSLSELRRLVPTAFEKQGS--AKLEKAEILQMTVDHLKMLQAT 60

Query: 282 XXXXXXXNPSVDVDRFRAGFTHAANEVSRCLASIPGVDVR--LGTQLMTHL 428
                    ++ +D    GF     EV+R L+S+ G+D    L  +L++HL
Sbjct: 61  GGKGYFDAHALAMDFMSIGFRECLTEVARYLSSVEGLDSSDPLRVRLVSHL 111


>AL078594-1|CAB87581.1|  337|Homo sapiens hairy/enhancer-of-split
           related with YRPW motif 2 protein.
          Length = 337

 Score = 58.8 bits (136), Expect = 2e-08
 Identities = 38/111 (34%), Positives = 61/111 (54%), Gaps = 4/111 (3%)
 Frame = +3

Query: 108 RKVMKPMLERKRRARINRCLDELKELMVSALQSEGENVAKLEKADILELTV--XXXXXXX 281
           RK  + ++E++RR RIN  L EL+ L+ +A + +G   AKLEKA+IL++TV         
Sbjct: 49  RKKRRGIIEKRRRDRINNSLSELRRLVPTAFEKQGS--AKLEKAEILQMTVDHLKMLQAT 106

Query: 282 XXXXXXXNPSVDVDRFRAGFTHAANEVSRCLASIPGVDVR--LGTQLMTHL 428
                    ++ +D    GF     EV+R L+S+ G+D    L  +L++HL
Sbjct: 107 GGKGYFDAHALAMDFMSIGFRECLTEVARYLSSVEGLDSSDPLRVRLVSHL 157


>AJ249545-1|CAB56839.1|  337|Homo sapiens basic-helix-loop-helix
           protein, bHLH protein.
          Length = 337

 Score = 58.8 bits (136), Expect = 2e-08
 Identities = 38/111 (34%), Positives = 61/111 (54%), Gaps = 4/111 (3%)
 Frame = +3

Query: 108 RKVMKPMLERKRRARINRCLDELKELMVSALQSEGENVAKLEKADILELTV--XXXXXXX 281
           RK  + ++E++RR RIN  L EL+ L+ +A + +G   AKLEKA+IL++TV         
Sbjct: 49  RKKRRGIIEKRRRDRINNSLSELRRLVPTAFEKQGS--AKLEKAEILQMTVDHLKMLQAT 106

Query: 282 XXXXXXXNPSVDVDRFRAGFTHAANEVSRCLASIPGVDVR--LGTQLMTHL 428
                    ++ +D    GF     EV+R L+S+ G+D    L  +L++HL
Sbjct: 107 GGKGYFDAHALAMDFMSIGFRECLTEVARYLSSVEGLDSSDPLRVRLVSHL 157


>AF311884-1|AAG31157.1|  337|Homo sapiens hairy-related
           transcription factor 2 protein.
          Length = 337

 Score = 58.8 bits (136), Expect = 2e-08
 Identities = 38/111 (34%), Positives = 61/111 (54%), Gaps = 4/111 (3%)
 Frame = +3

Query: 108 RKVMKPMLERKRRARINRCLDELKELMVSALQSEGENVAKLEKADILELTV--XXXXXXX 281
           RK  + ++E++RR RIN  L EL+ L+ +A + +G   AKLEKA+IL++TV         
Sbjct: 49  RKKRRGIIEKRRRDRINNSLSELRRLVPTAFEKQGS--AKLEKAEILQMTVDHLKMLQAT 106

Query: 282 XXXXXXXNPSVDVDRFRAGFTHAANEVSRCLASIPGVDVR--LGTQLMTHL 428
                    ++ +D    GF     EV+R L+S+ G+D    L  +L++HL
Sbjct: 107 GGKGYFDAHALAMDFMSIGFRECLTEVARYLSSVEGLDSSDPLRVRLVSHL 157


>AF237949-1|AAF44781.1|  337|Homo sapiens GRIDLOCK protein.
          Length = 337

 Score = 58.8 bits (136), Expect = 2e-08
 Identities = 38/111 (34%), Positives = 61/111 (54%), Gaps = 4/111 (3%)
 Frame = +3

Query: 108 RKVMKPMLERKRRARINRCLDELKELMVSALQSEGENVAKLEKADILELTV--XXXXXXX 281
           RK  + ++E++RR RIN  L EL+ L+ +A + +G   AKLEKA+IL++TV         
Sbjct: 49  RKKRRGIIEKRRRDRINNSLSELRRLVPTAFEKQGS--AKLEKAEILQMTVDHLKMLQAT 106

Query: 282 XXXXXXXNPSVDVDRFRAGFTHAANEVSRCLASIPGVDVR--LGTQLMTHL 428
                    ++ +D    GF     EV+R L+S+ G+D    L  +L++HL
Sbjct: 107 GGKGYFDAHALAMDFMSIGFRECLTEVARYLSSVEGLDSSDPLRVRLVSHL 157


>AF232238-1|AAF37296.1|  337|Homo sapiens HES-related repressor
           protein 1 HERP1 protein.
          Length = 337

 Score = 58.8 bits (136), Expect = 2e-08
 Identities = 38/111 (34%), Positives = 61/111 (54%), Gaps = 4/111 (3%)
 Frame = +3

Query: 108 RKVMKPMLERKRRARINRCLDELKELMVSALQSEGENVAKLEKADILELTV--XXXXXXX 281
           RK  + ++E++RR RIN  L EL+ L+ +A + +G   AKLEKA+IL++TV         
Sbjct: 49  RKKRRGIIEKRRRDRINNSLSELRRLVPTAFEKQGS--AKLEKAEILQMTVDHLKMLQAT 106

Query: 282 XXXXXXXNPSVDVDRFRAGFTHAANEVSRCLASIPGVDVR--LGTQLMTHL 428
                    ++ +D    GF     EV+R L+S+ G+D    L  +L++HL
Sbjct: 107 GGKGYFDAHALAMDFMSIGFRECLTEVARYLSSVEGLDSSDPLRVRLVSHL 157


>AF173901-1|AAF20173.1|  337|Homo sapiens basic helix-loop-helix
           factor 1 protein.
          Length = 337

 Score = 58.8 bits (136), Expect = 2e-08
 Identities = 38/111 (34%), Positives = 61/111 (54%), Gaps = 4/111 (3%)
 Frame = +3

Query: 108 RKVMKPMLERKRRARINRCLDELKELMVSALQSEGENVAKLEKADILELTV--XXXXXXX 281
           RK  + ++E++RR RIN  L EL+ L+ +A + +G   AKLEKA+IL++TV         
Sbjct: 49  RKKRRGIIEKRRRDRINNSLSELRRLVPTAFEKQGS--AKLEKAEILQMTVDHLKMLQAT 106

Query: 282 XXXXXXXNPSVDVDRFRAGFTHAANEVSRCLASIPGVDVR--LGTQLMTHL 428
                    ++ +D    GF     EV+R L+S+ G+D    L  +L++HL
Sbjct: 107 GGKGYFDAHALAMDFMSIGFRECLTEVARYLSSVEGLDSSDPLRVRLVSHL 157


>AB044755-1|BAA96781.1|  337|Homo sapiens basic-helix-loop-helix
           protein protein.
          Length = 337

 Score = 58.8 bits (136), Expect = 2e-08
 Identities = 38/111 (34%), Positives = 61/111 (54%), Gaps = 4/111 (3%)
 Frame = +3

Query: 108 RKVMKPMLERKRRARINRCLDELKELMVSALQSEGENVAKLEKADILELTV--XXXXXXX 281
           RK  + ++E++RR RIN  L EL+ L+ +A + +G   AKLEKA+IL++TV         
Sbjct: 49  RKKRRGIIEKRRRDRINNSLSELRRLVPTAFEKQGS--AKLEKAEILQMTVDHLKMLQAT 106

Query: 282 XXXXXXXNPSVDVDRFRAGFTHAANEVSRCLASIPGVDVR--LGTQLMTHL 428
                    ++ +D    GF     EV+R L+S+ G+D    L  +L++HL
Sbjct: 107 GGKGYFDAHALAMDFMSIGFRECLTEVARYLSSVEGLDSSDPLRVRLVSHL 157


>BT020065-1|AAV38868.1|  304|Homo sapiens hairy/enhancer-of-split
           related with YRPW motif 1 protein.
          Length = 304

 Score = 57.2 bits (132), Expect = 5e-08
 Identities = 39/113 (34%), Positives = 61/113 (53%), Gaps = 4/113 (3%)
 Frame = +3

Query: 108 RKVMKPMLERKRRARINRCLDELKELMVSALQSEGENVAKLEKADILELTV--XXXXXXX 281
           RK  + ++E++RR RIN  L EL+ L+ SA + +G   AKLEKA+IL++TV         
Sbjct: 50  RKRRRGIIEKRRRDRINNSLSELRRLVPSAFEKQGS--AKLEKAEILQMTVDHLKMLHTA 107

Query: 282 XXXXXXXNPSVDVDRFRAGFTHAANEVSRCLASIPGVDVR--LGTQLMTHLGH 434
                    ++ +D    GF     EV+R L+ I G+D    L  +L++HL +
Sbjct: 108 GGKGYFDAHALAMDYRSLGFRECLAEVARYLSIIEGLDASDPLRVRLVSHLNN 160


>BC001873-1|AAH01873.1|  304|Homo sapiens hairy/enhancer-of-split
           related with YRPW motif 1 protein.
          Length = 304

 Score = 57.2 bits (132), Expect = 5e-08
 Identities = 39/113 (34%), Positives = 61/113 (53%), Gaps = 4/113 (3%)
 Frame = +3

Query: 108 RKVMKPMLERKRRARINRCLDELKELMVSALQSEGENVAKLEKADILELTV--XXXXXXX 281
           RK  + ++E++RR RIN  L EL+ L+ SA + +G   AKLEKA+IL++TV         
Sbjct: 50  RKRRRGIIEKRRRDRINNSLSELRRLVPSAFEKQGS--AKLEKAEILQMTVDHLKMLHTA 107

Query: 282 XXXXXXXNPSVDVDRFRAGFTHAANEVSRCLASIPGVDVR--LGTQLMTHLGH 434
                    ++ +D    GF     EV+R L+ I G+D    L  +L++HL +
Sbjct: 108 GGKGYFDAHALAMDYRSLGFRECLAEVARYLSIIEGLDASDPLRVRLVSHLNN 160


>AJ272214-1|CAB75715.1|  304|Homo sapiens HEY1 protein protein.
          Length = 304

 Score = 57.2 bits (132), Expect = 5e-08
 Identities = 39/113 (34%), Positives = 61/113 (53%), Gaps = 4/113 (3%)
 Frame = +3

Query: 108 RKVMKPMLERKRRARINRCLDELKELMVSALQSEGENVAKLEKADILELTV--XXXXXXX 281
           RK  + ++E++RR RIN  L EL+ L+ SA + +G   AKLEKA+IL++TV         
Sbjct: 50  RKRRRGIIEKRRRDRINNSLSELRRLVPSAFEKQGS--AKLEKAEILQMTVDHLKMLHTA 107

Query: 282 XXXXXXXNPSVDVDRFRAGFTHAANEVSRCLASIPGVDVR--LGTQLMTHLGH 434
                    ++ +D    GF     EV+R L+ I G+D    L  +L++HL +
Sbjct: 108 GGKGYFDAHALAMDYRSLGFRECLAEVARYLSIIEGLDASDPLRVRLVSHLNN 160


>AF311883-1|AAG31156.1|  304|Homo sapiens hairy-related
           transcription factor 1 protein.
          Length = 304

 Score = 57.2 bits (132), Expect = 5e-08
 Identities = 39/113 (34%), Positives = 61/113 (53%), Gaps = 4/113 (3%)
 Frame = +3

Query: 108 RKVMKPMLERKRRARINRCLDELKELMVSALQSEGENVAKLEKADILELTV--XXXXXXX 281
           RK  + ++E++RR RIN  L EL+ L+ SA + +G   AKLEKA+IL++TV         
Sbjct: 50  RKRRRGIIEKRRRDRINNSLSELRRLVPSAFEKQGS--AKLEKAEILQMTVDHLKMLHTA 107

Query: 282 XXXXXXXNPSVDVDRFRAGFTHAANEVSRCLASIPGVDVR--LGTQLMTHLGH 434
                    ++ +D    GF     EV+R L+ I G+D    L  +L++HL +
Sbjct: 108 GGKGYFDAHALAMDYRSLGFRECLAEVARYLSIIEGLDASDPLRVRLVSHLNN 160


>AF254637-1|AAL06278.1|  304|Homo sapiens basic helix-loop-helix
           protein OAF1 protein.
          Length = 304

 Score = 57.2 bits (132), Expect = 5e-08
 Identities = 39/113 (34%), Positives = 61/113 (53%), Gaps = 4/113 (3%)
 Frame = +3

Query: 108 RKVMKPMLERKRRARINRCLDELKELMVSALQSEGENVAKLEKADILELTV--XXXXXXX 281
           RK  + ++E++RR RIN  L EL+ L+ SA + +G   AKLEKA+IL++TV         
Sbjct: 50  RKRRRGIIEKRRRDRINNSLSELRRLVPSAFEKQGS--AKLEKAEILQMTVDHLKMLHTA 107

Query: 282 XXXXXXXNPSVDVDRFRAGFTHAANEVSRCLASIPGVDVR--LGTQLMTHLGH 434
                    ++ +D    GF     EV+R L+ I G+D    L  +L++HL +
Sbjct: 108 GGKGYFDAHALAMDYRSLGFRECLAEVARYLSIIEGLDASDPLRVRLVSHLNN 160


>AF232239-1|AAF37297.1|  304|Homo sapiens HES-related repressor
           protein 2 HERP2 protein.
          Length = 304

 Score = 57.2 bits (132), Expect = 5e-08
 Identities = 39/113 (34%), Positives = 61/113 (53%), Gaps = 4/113 (3%)
 Frame = +3

Query: 108 RKVMKPMLERKRRARINRCLDELKELMVSALQSEGENVAKLEKADILELTV--XXXXXXX 281
           RK  + ++E++RR RIN  L EL+ L+ SA + +G   AKLEKA+IL++TV         
Sbjct: 50  RKRRRGIIEKRRRDRINNSLSELRRLVPSAFEKQGS--AKLEKAEILQMTVDHLKMLHTA 107

Query: 282 XXXXXXXNPSVDVDRFRAGFTHAANEVSRCLASIPGVDVR--LGTQLMTHLGH 434
                    ++ +D    GF     EV+R L+ I G+D    L  +L++HL +
Sbjct: 108 GGKGYFDAHALAMDYRSLGFRECLAEVARYLSIIEGLDASDPLRVRLVSHLNN 160


>AF176422-1|AAD51749.1|  304|Homo sapiens cardiovascular
           helix-loop-helix factor 2 protein.
          Length = 304

 Score = 57.2 bits (132), Expect = 5e-08
 Identities = 39/113 (34%), Positives = 61/113 (53%), Gaps = 4/113 (3%)
 Frame = +3

Query: 108 RKVMKPMLERKRRARINRCLDELKELMVSALQSEGENVAKLEKADILELTV--XXXXXXX 281
           RK  + ++E++RR RIN  L EL+ L+ SA + +G   AKLEKA+IL++TV         
Sbjct: 50  RKRRRGIIEKRRRDRINNSLSELRRLVPSAFEKQGS--AKLEKAEILQMTVDHLKMLHTA 107

Query: 282 XXXXXXXNPSVDVDRFRAGFTHAANEVSRCLASIPGVDVR--LGTQLMTHLGH 434
                    ++ +D    GF     EV+R L+ I G+D    L  +L++HL +
Sbjct: 108 GGKGYFDAHALAMDYRSLGFRECLAEVARYLSIIEGLDASDPLRVRLVSHLNN 160


>AF151522-1|AAD38967.1|  304|Homo sapiens hairy and enhancer of
           split related-1 protein.
          Length = 304

 Score = 57.2 bits (132), Expect = 5e-08
 Identities = 39/113 (34%), Positives = 61/113 (53%), Gaps = 4/113 (3%)
 Frame = +3

Query: 108 RKVMKPMLERKRRARINRCLDELKELMVSALQSEGENVAKLEKADILELTV--XXXXXXX 281
           RK  + ++E++RR RIN  L EL+ L+ SA + +G   AKLEKA+IL++TV         
Sbjct: 50  RKRRRGIIEKRRRDRINNSLSELRRLVPSAFEKQGS--AKLEKAEILQMTVDHLKMLHTA 107

Query: 282 XXXXXXXNPSVDVDRFRAGFTHAANEVSRCLASIPGVDVR--LGTQLMTHLGH 434
                    ++ +D    GF     EV+R L+ I G+D    L  +L++HL +
Sbjct: 108 GGKGYFDAHALAMDYRSLGFRECLAEVARYLSIIEGLDASDPLRVRLVSHLNN 160


>BC006087-1|AAH06087.1|  328|Homo sapiens hairy/enhancer-of-split
           related with YRPW motif-like protein.
          Length = 328

 Score = 54.4 bits (125), Expect = 3e-07
 Identities = 39/128 (30%), Positives = 63/128 (49%), Gaps = 5/128 (3%)
 Frame = +3

Query: 84  PVSRTYQYRKVMKPMLERKRRARINRCLDELKELMVSALQSEGENVAKLEKADILELTV- 260
           P S   Q RK  + ++E++RR RIN  L EL+ L+ +A + +G   +KLEKA++L++TV 
Sbjct: 36  PSSSQMQARKKRRGIIEKRRRDRINSSLSELRRLVPTAFEKQGS--SKLEKAEVLQMTVD 93

Query: 261 -XXXXXXXXXXXXXXNPSVDVDRFRAGFTHAANEVSRCLASIPGVDVR---LGTQLMTHL 428
                            ++ VD    GF     EV R L  + G   R   +  +L++HL
Sbjct: 94  HLKMLHATGGTGFFDARALAVDFRSIGFRECLTEVIRYLGVLEGPSSRADPVRIRLLSHL 153

Query: 429 GHRLNDMQ 452
                +M+
Sbjct: 154 NSYAAEME 161


>AJ272215-1|CAB75716.1|  328|Homo sapiens HEYL protein protein.
          Length = 328

 Score = 54.4 bits (125), Expect = 3e-07
 Identities = 39/128 (30%), Positives = 63/128 (49%), Gaps = 5/128 (3%)
 Frame = +3

Query: 84  PVSRTYQYRKVMKPMLERKRRARINRCLDELKELMVSALQSEGENVAKLEKADILELTV- 260
           P S   Q RK  + ++E++RR RIN  L EL+ L+ +A + +G   +KLEKA++L++TV 
Sbjct: 36  PSSSQMQARKKRRGIIEKRRRDRINSSLSELRRLVPTAFEKQGS--SKLEKAEVLQMTVD 93

Query: 261 -XXXXXXXXXXXXXXNPSVDVDRFRAGFTHAANEVSRCLASIPGVDVR---LGTQLMTHL 428
                            ++ VD    GF     EV R L  + G   R   +  +L++HL
Sbjct: 94  HLKMLHATGGTGFFDARALAVDFRSIGFRECLTEVIRYLGVLEGPSSRADPVRIRLLSHL 153

Query: 429 GHRLNDMQ 452
                +M+
Sbjct: 154 NSYAAEME 161


>AF311885-1|AAG31158.1|  328|Homo sapiens hairy-related
           transcription factor 3 protein.
          Length = 328

 Score = 54.4 bits (125), Expect = 3e-07
 Identities = 39/128 (30%), Positives = 63/128 (49%), Gaps = 5/128 (3%)
 Frame = +3

Query: 84  PVSRTYQYRKVMKPMLERKRRARINRCLDELKELMVSALQSEGENVAKLEKADILELTV- 260
           P S   Q RK  + ++E++RR RIN  L EL+ L+ +A + +G   +KLEKA++L++TV 
Sbjct: 36  PSSSQMQARKKRRGIIEKRRRDRINSSLSELRRLVPTAFEKQGS--SKLEKAEVLQMTVD 93

Query: 261 -XXXXXXXXXXXXXXNPSVDVDRFRAGFTHAANEVSRCLASIPGVDVR---LGTQLMTHL 428
                            ++ VD    GF     EV R L  + G   R   +  +L++HL
Sbjct: 94  HLKMLHATGGTGFFDARALAVDFRSIGFRECLTEVIRYLGVLEGPSSRADPVRIRLLSHL 153

Query: 429 GHRLNDMQ 452
                +M+
Sbjct: 154 NSYAAEME 161


>AL035404-1|CAI19572.1|  328|Homo sapiens hairy/enhancer-of-split
           related with YRPW motif-like protein.
          Length = 328

 Score = 54.0 bits (124), Expect = 4e-07
 Identities = 39/128 (30%), Positives = 63/128 (49%), Gaps = 5/128 (3%)
 Frame = +3

Query: 84  PVSRTYQYRKVMKPMLERKRRARINRCLDELKELMVSALQSEGENVAKLEKADILELTV- 260
           P S   Q RK  + ++E++RR RIN  L EL+ L+ +A + +G   +KLEKA++L++TV 
Sbjct: 36  PSSSQMQARKKHRGIIEKRRRDRINSSLSELRRLVPTAFEKQGS--SKLEKAEVLQMTVD 93

Query: 261 -XXXXXXXXXXXXXXNPSVDVDRFRAGFTHAANEVSRCLASIPGVDVR---LGTQLMTHL 428
                            ++ VD    GF     EV R L  + G   R   +  +L++HL
Sbjct: 94  HLKMLHATGGTGFFDARALAVDFRSIGFRECLTEVIRYLGVLEGPSSRADPVRIRLLSHL 153

Query: 429 GHRLNDMQ 452
                +M+
Sbjct: 154 NSYAAEME 161


>AK092437-1|BAC03890.1|  308|Homo sapiens protein ( Homo sapiens
           cDNA FLJ35118 fis, clone PLACE6007436, highly similar to
           Homo sapiens hairy and enhancer of split related-1
           (HESR-1) ).
          Length = 308

 Score = 54.0 bits (124), Expect = 4e-07
 Identities = 38/115 (33%), Positives = 61/115 (53%), Gaps = 6/115 (5%)
 Frame = +3

Query: 108 RKVMKPMLERKRRARINRCLDELKELMVSALQSE--GENVAKLEKADILELTV--XXXXX 275
           RK  + ++E++RR RIN  L EL+ L+ SA + +   +  AKLEKA+IL++TV       
Sbjct: 50  RKRRRGIIEKRRRDRINNSLSELRRLVPSAFEKQVMEQGSAKLEKAEILQMTVDHLKMLH 109

Query: 276 XXXXXXXXXNPSVDVDRFRAGFTHAANEVSRCLASIPGVDVR--LGTQLMTHLGH 434
                      ++ +D    GF     EV+R L+ I G+D    L  +L++HL +
Sbjct: 110 TAGGKGYFDAHALAMDYRSLGFRECLAEVARYLSIIEGLDASDPLRVRLVSHLNN 164


>AK075040-1|BAC11368.1|  214|Homo sapiens protein ( Homo sapiens
           cDNA FLJ90559 fis, clone OVARC1001049, weakly similar to
           TRANSCRIPTION FACTOR HES-1 (C-HAIRY1). ).
          Length = 214

 Score = 50.8 bits (116), Expect = 4e-06
 Identities = 28/51 (54%), Positives = 35/51 (68%)
 Frame = +3

Query: 108 RKVMKPMLERKRRARINRCLDELKELMVSALQSEGENVAKLEKADILELTV 260
           RK  KP++E+KRRARIN  L EL+ L+  A     E  AKLE A++LELTV
Sbjct: 26  RKARKPLVEKKRRARINESLQELRLLLAGA-----EVQAKLENAEVLELTV 71


>AB049064-1|BAB39525.1|  225|Homo sapiens bHLH factor Hes7 protein.
          Length = 225

 Score = 50.8 bits (116), Expect = 4e-06
 Identities = 23/50 (46%), Positives = 36/50 (72%)
 Frame = +3

Query: 111 KVMKPMLERKRRARINRCLDELKELMVSALQSEGENVAKLEKADILELTV 260
           K++KP++E++RR RINR L+EL+ L++   + +     KLEKA+ILE  V
Sbjct: 14  KMLKPLVEKRRRDRINRSLEELRLLLLERTRDQNLRNPKLEKAEILEFAV 63


>DQ272660-1|ABB83829.1|  166|Homo sapiens HES5 protein.
          Length = 166

 Score = 43.6 bits (98), Expect = 6e-04
 Identities = 28/98 (28%), Positives = 46/98 (46%)
 Frame = +3

Query: 111 KVMKPMLERKRRARINRCLDELKELMVSALQSEGENVAKLEKADILELTVXXXXXXXXXX 290
           ++ KP++E+ RR RIN  +++LK L+         N +KLEKADILE+ V          
Sbjct: 18  RLRKPVVEKMRRDRINSSIEQLKLLLEQEFARHQPN-SKLEKADILEMAVSYLKHSKAFV 76

Query: 291 XXXXNPSVDVDRFRAGFTHAANEVSRCLASIPGVDVRL 404
                 S+  D +  G++    E  + L      D ++
Sbjct: 77  AAAGPKSLHQD-YSEGYSWCLQEAVQFLTLHAASDTQM 113


>AL031847-3|CAI19439.1|  180|Homo sapiens hairy and enhancer of
           split 3 (Drosophila) protein.
          Length = 180

 Score = 41.5 bits (93), Expect = 0.003
 Identities = 24/44 (54%), Positives = 30/44 (68%)
 Frame = +3

Query: 129 LERKRRARINRCLDELKELMVSALQSEGENVAKLEKADILELTV 260
           +E+KRRARIN  L++LK L+     S      KLEKADILEL+V
Sbjct: 1   MEKKRRARINVSLEQLKSLL-EKHYSHQIRKRKLEKADILELSV 43


>BC012091-1|AAH12091.1|   76|Homo sapiens HES2 protein protein.
          Length = 76

 Score = 41.1 bits (92), Expect = 0.003
 Identities = 19/44 (43%), Positives = 29/44 (65%)
 Frame = +3

Query: 78  PQPVSRTYQYRKVMKPMLERKRRARINRCLDELKELMVSALQSE 209
           P+      + RK +KP+LE++RRARIN+ L +LK L++  L  E
Sbjct: 4   PRRAGDAAELRKSLKPLLEKRRRARINQSLSQLKGLILPLLGRE 47


>AL031848-5|CAB46199.1|   76|Homo sapiens hairy and enhancer of
           split 2 (Drosophila) protein.
          Length = 76

 Score = 41.1 bits (92), Expect = 0.003
 Identities = 19/44 (43%), Positives = 29/44 (65%)
 Frame = +3

Query: 78  PQPVSRTYQYRKVMKPMLERKRRARINRCLDELKELMVSALQSE 209
           P+      + RK +KP+LE++RRARIN+ L +LK L++  L  E
Sbjct: 4   PRRAGDAAELRKSLKPLLEKRRRARINQSLSQLKGLILPLLGRE 47


>EF015896-1|ABM64207.1|  482|Homo sapiens basic helix-loop-helix
           domain-containing protein.
          Length = 482

 Score = 40.3 bits (90), Expect = 0.006
 Identities = 21/50 (42%), Positives = 33/50 (66%)
 Frame = +3

Query: 111 KVMKPMLERKRRARINRCLDELKELMVSALQSEGENVAKLEKADILELTV 260
           K+   ++E+KRR RIN C+ +LK+L+   L+     +  LEKA +LELT+
Sbjct: 46  KLPHRLIEKKRRDRINECIAQLKDLLPEHLKL--TTLGHLEKAVVLELTL 93


>EF015895-1|ABM64206.1|  412|Homo sapiens basic helix-loop-helix
           domain-containing protein.
          Length = 412

 Score = 40.3 bits (90), Expect = 0.006
 Identities = 21/50 (42%), Positives = 33/50 (66%)
 Frame = +3

Query: 111 KVMKPMLERKRRARINRCLDELKELMVSALQSEGENVAKLEKADILELTV 260
           K+   ++E+KRR RIN C+ +LK+L+   L+     +  LEKA +LELT+
Sbjct: 54  KLPHRLIEKKRRDRINECIAQLKDLLPEHLKL--TTLGHLEKAVVLELTL 101


>CR456921-1|CAG33202.1|  412|Homo sapiens BHLHB2 protein.
          Length = 412

 Score = 40.3 bits (90), Expect = 0.006
 Identities = 21/50 (42%), Positives = 33/50 (66%)
 Frame = +3

Query: 111 KVMKPMLERKRRARINRCLDELKELMVSALQSEGENVAKLEKADILELTV 260
           K+   ++E+KRR RIN C+ +LK+L+   L+     +  LEKA +LELT+
Sbjct: 54  KLPHRLIEKKRRDRINECIAQLKDLLPEHLKL--TTLGHLEKAVVLELTL 101


>BC082238-1|AAH82238.1|  412|Homo sapiens basic helix-loop-helix
           domain containing, class B, 2 protein.
          Length = 412

 Score = 40.3 bits (90), Expect = 0.006
 Identities = 21/50 (42%), Positives = 33/50 (66%)
 Frame = +3

Query: 111 KVMKPMLERKRRARINRCLDELKELMVSALQSEGENVAKLEKADILELTV 260
           K+   ++E+KRR RIN C+ +LK+L+   L+     +  LEKA +LELT+
Sbjct: 54  KLPHRLIEKKRRDRINECIAQLKDLLPEHLKL--TTLGHLEKAVVLELTL 101


>BC025968-1|AAH25968.1|  482|Homo sapiens basic helix-loop-helix
           domain containing, class B, 3 protein.
          Length = 482

 Score = 40.3 bits (90), Expect = 0.006
 Identities = 21/50 (42%), Positives = 33/50 (66%)
 Frame = +3

Query: 111 KVMKPMLERKRRARINRCLDELKELMVSALQSEGENVAKLEKADILELTV 260
           K+   ++E+KRR RIN C+ +LK+L+   L+     +  LEKA +LELT+
Sbjct: 46  KLPHRLIEKKRRDRINECIAQLKDLLPEHLKL--TTLGHLEKAVVLELTL 93


>AY665467-1|AAV54602.1|  482|Homo sapiens basic helix-loop-helix
           protein 3 isoform 1 protein.
          Length = 482

 Score = 40.3 bits (90), Expect = 0.006
 Identities = 21/50 (42%), Positives = 33/50 (66%)
 Frame = +3

Query: 111 KVMKPMLERKRRARINRCLDELKELMVSALQSEGENVAKLEKADILELTV 260
           K+   ++E+KRR RIN C+ +LK+L+   L+     +  LEKA +LELT+
Sbjct: 46  KLPHRLIEKKRRDRINECIAQLKDLLPEHLKL--TTLGHLEKAVVLELTL 93


>AF353635-1|AAK49525.1|  409|Homo sapiens bHLH transcription factor
           DEC1 protein.
          Length = 409

 Score = 40.3 bits (90), Expect = 0.006
 Identities = 21/50 (42%), Positives = 33/50 (66%)
 Frame = +3

Query: 111 KVMKPMLERKRRARINRCLDELKELMVSALQSEGENVAKLEKADILELTV 260
           K+   ++E+KRR RIN C+ +LK+L+   L+     +  LEKA +LELT+
Sbjct: 51  KLPHRLIEKKRRDRINECIAQLKDLLPEHLKL--TTLGHLEKAVVLELTL 98


>AB044088-1|BAB21502.1|  482|Homo sapiens bHLH protein DEC2 protein.
          Length = 482

 Score = 40.3 bits (90), Expect = 0.006
 Identities = 21/50 (42%), Positives = 33/50 (66%)
 Frame = +3

Query: 111 KVMKPMLERKRRARINRCLDELKELMVSALQSEGENVAKLEKADILELTV 260
           K+   ++E+KRR RIN C+ +LK+L+   L+     +  LEKA +LELT+
Sbjct: 46  KLPHRLIEKKRRDRINECIAQLKDLLPEHLKL--TTLGHLEKAVVLELTL 93


>AB043885-1|BAB18565.1|  412|Homo sapiens bHLH transcriptional
           factor DEC1 protein.
          Length = 412

 Score = 40.3 bits (90), Expect = 0.006
 Identities = 21/50 (42%), Positives = 33/50 (66%)
 Frame = +3

Query: 111 KVMKPMLERKRRARINRCLDELKELMVSALQSEGENVAKLEKADILELTV 260
           K+   ++E+KRR RIN C+ +LK+L+   L+     +  LEKA +LELT+
Sbjct: 54  KLPHRLIEKKRRDRINECIAQLKDLLPEHLKL--TTLGHLEKAVVLELTL 101


>AB004066-1|BAA21720.1|  412|Homo sapiens DEC1 protein.
          Length = 412

 Score = 40.3 bits (90), Expect = 0.006
 Identities = 21/50 (42%), Positives = 33/50 (66%)
 Frame = +3

Query: 111 KVMKPMLERKRRARINRCLDELKELMVSALQSEGENVAKLEKADILELTV 260
           K+   ++E+KRR RIN C+ +LK+L+   L+     +  LEKA +LELT+
Sbjct: 54  KLPHRLIEKKRRDRINECIAQLKDLLPEHLKL--TTLGHLEKAVVLELTL 101


>AL670729-4|CAH71670.2| 2582|Homo sapiens obscurin, cytoskeletal
           calmodulin and titin-interacting RhoGEF protein.
          Length = 2582

 Score = 35.1 bits (77), Expect = 0.22
 Identities = 18/46 (39%), Positives = 25/46 (54%)
 Frame = +3

Query: 81  QPVSRTYQYRKVMKPMLERKRRARINRCLDELKELMVSALQSEGEN 218
           QPV R  +Y+ ++K ++  K R R N  L E    +VSAL    EN
Sbjct: 447 QPVERVQRYQALLKELIRNKARNRQNCALLEQAYAVVSALPQRAEN 492


>AL670729-3|CAH71673.1| 6620|Homo sapiens obscurin, cytoskeletal
            calmodulin and titin-interacting RhoGEF protein.
          Length = 6620

 Score = 35.1 bits (77), Expect = 0.22
 Identities = 18/46 (39%), Positives = 25/46 (54%)
 Frame = +3

Query: 81   QPVSRTYQYRKVMKPMLERKRRARINRCLDELKELMVSALQSEGEN 218
            QPV R  +Y+ ++K ++  K R R N  L E    +VSAL    EN
Sbjct: 5831 QPVERVQRYQALLKELIRNKARNRQNCALLEQAYAVVSALPQRAEN 5876


>AL359510-13|CAI15072.1| 6620|Homo sapiens obscurin, cytoskeletal
            calmodulin and titin-interacting RhoGEF protein.
          Length = 6620

 Score = 35.1 bits (77), Expect = 0.22
 Identities = 18/46 (39%), Positives = 25/46 (54%)
 Frame = +3

Query: 81   QPVSRTYQYRKVMKPMLERKRRARINRCLDELKELMVSALQSEGEN 218
            QPV R  +Y+ ++K ++  K R R N  L E    +VSAL    EN
Sbjct: 5831 QPVERVQRYQALLKELIRNKARNRQNCALLEQAYAVVSALPQRAEN 5876


>AL353593-4|CAM27610.1| 2582|Homo sapiens obscurin, cytoskeletal
           calmodulin and titin-interacting RhoGEF protein.
          Length = 2582

 Score = 35.1 bits (77), Expect = 0.22
 Identities = 18/46 (39%), Positives = 25/46 (54%)
 Frame = +3

Query: 81  QPVSRTYQYRKVMKPMLERKRRARINRCLDELKELMVSALQSEGEN 218
           QPV R  +Y+ ++K ++  K R R N  L E    +VSAL    EN
Sbjct: 447 QPVERVQRYQALLKELIRNKARNRQNCALLEQAYAVVSALPQRAEN 492


>AL353593-3|CAI19285.1| 6620|Homo sapiens obscurin, cytoskeletal
            calmodulin and titin-interacting RhoGEF protein.
          Length = 6620

 Score = 35.1 bits (77), Expect = 0.22
 Identities = 18/46 (39%), Positives = 25/46 (54%)
 Frame = +3

Query: 81   QPVSRTYQYRKVMKPMLERKRRARINRCLDELKELMVSALQSEGEN 218
            QPV R  +Y+ ++K ++  K R R N  L E    +VSAL    EN
Sbjct: 5831 QPVERVQRYQALLKELIRNKARNRQNCALLEQAYAVVSALPQRAEN 5876


>AJ314908-1|CAC85755.1| 1020|Homo sapiens obscurin protein.
          Length = 1020

 Score = 35.1 bits (77), Expect = 0.22
 Identities = 18/46 (39%), Positives = 25/46 (54%)
 Frame = +3

Query: 81  QPVSRTYQYRKVMKPMLERKRRARINRCLDELKELMVSALQSEGEN 218
           QPV R  +Y+ ++K ++  K R R N  L E    +VSAL    EN
Sbjct: 231 QPVERVQRYQALLKELIRNKARNRQNCALLEQAYAVVSALPQRAEN 276


>AJ002535-1|CAC44768.1| 6620|Homo sapiens obscurin protein.
          Length = 6620

 Score = 35.1 bits (77), Expect = 0.22
 Identities = 18/46 (39%), Positives = 25/46 (54%)
 Frame = +3

Query: 81   QPVSRTYQYRKVMKPMLERKRRARINRCLDELKELMVSALQSEGEN 218
            QPV R  +Y+ ++K ++  K R R N  L E    +VSAL    EN
Sbjct: 5831 QPVERVQRYQALLKELIRNKARNRQNCALLEQAYAVVSALPQRAEN 5876


>AB046859-1|BAB13465.2| 2584|Homo sapiens KIAA1639 protein protein.
          Length = 2584

 Score = 35.1 bits (77), Expect = 0.22
 Identities = 18/46 (39%), Positives = 25/46 (54%)
 Frame = +3

Query: 81  QPVSRTYQYRKVMKPMLERKRRARINRCLDELKELMVSALQSEGEN 218
           QPV R  +Y+ ++K ++  K R R N  L E    +VSAL    EN
Sbjct: 447 QPVERVQRYQALLKELIRNKARNRQNCALLEQAYAVVSALPQRAEN 492


>BC087840-1|AAH87840.1|  172|Homo sapiens HES5 protein protein.
          Length = 172

 Score = 34.3 bits (75), Expect = 0.38
 Identities = 19/40 (47%), Positives = 25/40 (62%)
 Frame = +3

Query: 141 RRARINRCLDELKELMVSALQSEGENVAKLEKADILELTV 260
           RR RIN  +++LK L+         N +KLEKADILE+ V
Sbjct: 2   RRDRINSSIEQLKLLLEQEFARHQPN-SKLEKADILEMAV 40


>BC032586-1|AAH32586.1|  363|Homo sapiens MXD3 protein protein.
          Length = 363

 Score = 29.9 bits (64), Expect = 8.2
 Identities = 11/20 (55%), Positives = 17/20 (85%)
 Frame = +3

Query: 129 LERKRRARINRCLDELKELM 188
           LE++RRA++ RCL+ LK+ M
Sbjct: 65  LEKRRRAQLKRCLERLKQQM 84


>BC000745-1|AAH00745.1|  206|Homo sapiens MAX dimerization protein 3
           protein.
          Length = 206

 Score = 29.9 bits (64), Expect = 8.2
 Identities = 11/20 (55%), Positives = 17/20 (85%)
 Frame = +3

Query: 129 LERKRRARINRCLDELKELM 188
           LE++RRA++ RCL+ LK+ M
Sbjct: 65  LEKRRRAQLKRCLERLKQQM 84


>AK222579-1|BAD96299.1|  206|Homo sapiens MAX dimerization protein 3
           variant protein.
          Length = 206

 Score = 29.9 bits (64), Expect = 8.2
 Identities = 11/20 (55%), Positives = 17/20 (85%)
 Frame = +3

Query: 129 LERKRRARINRCLDELKELM 188
           LE++RRA++ RCL+ LK+ M
Sbjct: 65  LEKRRRAQLKRCLERLKQQM 84


>AK057034-1|BAB71352.1|  193|Homo sapiens protein ( Homo sapiens
           cDNA FLJ32472 fis, clone SKNMC2000356, highly similar to
           Mus musculus Max-interacting transcriptional repressor
           (Mad3) ).
          Length = 193

 Score = 29.9 bits (64), Expect = 8.2
 Identities = 11/20 (55%), Positives = 17/20 (85%)
 Frame = +3

Query: 129 LERKRRARINRCLDELKELM 188
           LE++RRA++ RCL+ LK+ M
Sbjct: 65  LEKRRRAQLKRCLERLKQQM 84


>AF114834-1|AAP97233.1|  206|Homo sapiens Myx protein.
          Length = 206

 Score = 29.9 bits (64), Expect = 8.2
 Identities = 11/20 (55%), Positives = 17/20 (85%)
 Frame = +3

Query: 129 LERKRRARINRCLDELKELM 188
           LE++RRA++ RCL+ LK+ M
Sbjct: 65  LEKRRRAQLKRCLERLKQQM 84


  Database: human
    Posted date:  Oct 23, 2007  1:18 PM
  Number of letters in database: 76,859,062
  Number of sequences in database:  237,096
  
Lambda     K      H
   0.318    0.134    0.401 

Gapped
Lambda     K      H
   0.279   0.0580    0.190 


Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 97,714,010
Number of Sequences: 237096
Number of extensions: 2058172
Number of successful extensions: 5350
Number of sequences better than 10.0: 69
Number of HSP's better than 10.0 without gapping: 5032
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 5302
length of database: 76,859,062
effective HSP length: 87
effective length of database: 56,231,710
effective search space used: 7253890590
frameshift window, decay const: 40,  0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)

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