BLASTX 2.2.12 [Aug-07-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= I10A02NGRL0003_D02 (534 letters) Database: human 237,096 sequences; 76,859,062 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value X62515-1|CAA44373.1| 4393|Homo sapiens Human basement membrane h... 101 2e-21 M85289-1|AAA52700.1| 4391|Homo sapiens heparan sulfate proteogly... 101 2e-21 BC109204-1|AAI09205.1| 351|Homo sapiens HSPG2 protein protein. 101 2e-21 AL590556-2|CAH71870.1| 4391|Homo sapiens heparan sulfate proteog... 101 2e-21 AL590103-2|CAI12125.1| 4391|Homo sapiens heparan sulfate proteog... 101 2e-21 AL445795-1|CAC18534.1| 4370|Homo sapiens heparan sulfate proteog... 101 2e-21 AB209851-1|BAD93088.1| 2331|Homo sapiens Basement membrane-speci... 101 2e-21 U97669-1|AAB91371.1| 2321|Homo sapiens Notch3 protein. 75 2e-13 AF058900-1|AAC14346.1| 2321|Homo sapiens Notch3 protein. 75 2e-13 AC004663-1|AAC15789.1| 2281|Homo sapiens Notch 3 protein. 75 2e-13 BC146759-1|AAI46760.1| 1523|Homo sapiens slit homolog 3 (Drosoph... 73 5e-13 BC063620-1|AAH63620.1| 488|Homo sapiens AGRN protein protein. 73 5e-13 BC007649-1|AAH07649.1| 488|Homo sapiens AGRN protein protein. 73 5e-13 AY358884-1|AAQ89243.1| 1523|Homo sapiens SLIT3 protein. 73 5e-13 AL645608-13|CAI15575.2| 2045|Homo sapiens agrin protein. 73 5e-13 AF075240-1|AAD19336.1| 850|Homo sapiens SLIT1 protein protein. 73 5e-13 AF016903-1|AAC39776.1| 2026|Homo sapiens agrin precursor protein. 73 5e-13 AB191264-1|BAD52440.1| 2045|Homo sapiens agrin protein. 73 5e-13 AB017169-1|BAA35186.1| 1523|Homo sapiens Slit-3 protein protein. 73 5e-13 AB011538-1|BAA32466.2| 1559|Homo sapiens MEGF5 protein. 73 5e-13 U77720-1|AAC51323.1| 1214|Homo sapiens transmembrane protein Jag... 72 1e-12 U73936-1|AAC52020.1| 1218|Homo sapiens Jagged 1 protein. 72 1e-12 U61276-1|AAB39007.1| 1218|Homo sapiens transmembrane protein Jag... 72 1e-12 BC126207-1|AAI26208.1| 1218|Homo sapiens jagged 1 (Alagille synd... 72 1e-12 BC126205-1|AAI26206.1| 1218|Homo sapiens jagged 1 (Alagille synd... 72 1e-12 BC098393-1|AAH98393.1| 1218|Homo sapiens jagged 1 (Alagille synd... 72 1e-12 AL035456-3|CAC07198.1| 1218|Homo sapiens jagged 1 (Alagille synd... 72 1e-12 AF028593-1|AAB84053.1| 1218|Homo sapiens transmembrane protein J... 72 1e-12 BC146761-1|AAI46762.1| 1534|Homo sapiens slit homolog 1 (Drosoph... 71 2e-12 AL512424-5|CAI14258.1| 1534|Homo sapiens slit homolog 1 (Drosoph... 71 2e-12 AL512424-4|CAI14259.1| 1461|Homo sapiens slit homolog 1 (Drosoph... 71 2e-12 AL442123-4|CAH70918.1| 1534|Homo sapiens slit homolog 1 (Drosoph... 71 2e-12 AL442123-3|CAH70917.1| 1461|Homo sapiens slit homolog 1 (Drosoph... 71 2e-12 AL050329-2|CAB99359.1| 399|Homo sapiens protein ( Human DNA seq... 71 2e-12 AB017167-1|BAA35184.1| 1534|Homo sapiens Slit-1 protein protein. 71 2e-12 AB011537-1|BAA32465.3| 1618|Homo sapiens MEGF4 protein. 71 2e-12 BC071562-1|AAH71562.2| 1235|Homo sapiens NOTCH2 protein protein. 71 3e-12 AL596222-1|CAH70182.1| 2471|Homo sapiens Notch homolog 2 (Drosop... 71 3e-12 AL512503-1|CAH72483.1| 2471|Homo sapiens Notch homolog 2 (Drosop... 71 3e-12 AL359752-4|CAI18974.1| 2471|Homo sapiens Notch homolog 2 (Drosop... 71 3e-12 AF315356-1|AAG37073.1| 2471|Homo sapiens NOTCH2 protein protein. 71 3e-12 AF308601-1|AAA36377.2| 2471|Homo sapiens NOTCH 2 protein. 71 3e-12 AF003837-1|AAC51731.1| 1218|Homo sapiens Jagged1 protein. 70 5e-12 AY043325-1|AAL10682.1| 1406|Homo sapiens CRB1 isoform II precurs... 70 6e-12 AY043324-1|AAL10681.1| 1376|Homo sapiens CRB1 isoform I precurso... 70 6e-12 AL513325-2|CAH72584.1| 1406|Homo sapiens crumbs homolog 1 (Droso... 70 6e-12 AL139136-2|CAI15311.1| 1406|Homo sapiens crumbs homolog 1 (Droso... 70 6e-12 AL136322-3|CAI16646.1| 1406|Homo sapiens crumbs homolog 1 (Droso... 70 6e-12 AF154671-1|AAF01361.1| 1376|Homo sapiens CRB1 protein. 70 6e-12 AB208923-1|BAD92160.1| 441|Homo sapiens crumbs homolog 1 isofor... 70 6e-12 AY358892-1|AAQ89251.1| 723|Homo sapiens DLL1 protein. 69 8e-12 AL078605-2|CAB89569.1| 723|Homo sapiens delta-like 1 (Drosophil... 69 8e-12 AF222310-1|AAG09716.1| 723|Homo sapiens Delta1 protein. 69 8e-12 AF196571-1|AAF05834.1| 723|Homo sapiens Delta-like-1 protein pr... 69 8e-12 AF003522-1|AAB61286.1| 723|Homo sapiens Delta protein. 69 8e-12 BC117190-1|AAI17191.1| 1529|Homo sapiens slit homolog 2 (Drosoph... 69 1e-11 AL592301-5|CAI13934.1| 2555|Homo sapiens Notch homolog 1, transl... 69 1e-11 AL354671-1|CAI16149.1| 2555|Homo sapiens Notch homolog 1, transl... 69 1e-11 AF133270-1|AAD25539.1| 1525|Homo sapiens SLIT2 protein. 69 1e-11 AF055585-1|AAD04309.1| 1521|Homo sapiens neurogenic extracellula... 69 1e-11 AB017168-1|BAA35185.1| 1529|Homo sapiens Slit-2 protein protein. 69 1e-11 BC039143-1|AAH39143.1| 740|Homo sapiens FAT2 protein protein. 69 1e-11 AF231022-1|AAF61928.1| 4349|Homo sapiens protocadherin Fat 2 pro... 69 1e-11 AB177851-1|BAD66829.1| 573|Homo sapiens KIAA0811 splice variant... 69 1e-11 AB011535-1|BAA32463.1| 573|Homo sapiens MEGF1 protein. 69 1e-11 AL645608-14|CAI15576.1| 270|Homo sapiens agrin protein. 68 2e-11 AB209873-1|BAD93110.1| 2067|Homo sapiens notch1 preproprotein va... 68 2e-11 AB160984-1|BAD08246.1| 1123|Homo sapiens KIAA0811 protein protein. 68 2e-11 AB209447-1|BAD92684.1| 1289|Homo sapiens Notch homolog 3 variant... 67 3e-11 BC133013-1|AAI33014.1| 594|Homo sapiens EGF-like-domain, multip... 66 7e-11 BC133011-1|AAI33012.1| 594|Homo sapiens EGF-like-domain, multip... 66 7e-11 BC106950-1|AAI06951.1| 685|Homo sapiens delta-like 4 (Drosophil... 66 7e-11 AY358894-1|AAQ89253.1| 685|Homo sapiens DLL4 protein. 66 7e-11 AY358133-1|AAQ88500.1| 594|Homo sapiens TDKS9424 protein. 66 7e-11 AY243503-1|AAQ89957.1| 3574|Homo sapiens selectin-like protein p... 66 7e-11 AL592463-2|CAH73558.1| 3548|Homo sapiens sushi, von Willebrand f... 66 7e-11 AL589916-3|CAM13294.1| 594|Homo sapiens EGF-like-domain, multip... 66 7e-11 AL589916-2|CAI12363.2| 619|Homo sapiens EGF-like-domain, multip... 66 7e-11 AL365217-4|CAM23289.1| 594|Homo sapiens EGF-like-domain, multip... 66 7e-11 AL365217-3|CAI16606.1| 619|Homo sapiens EGF-like-domain, multip... 66 7e-11 AL354982-2|CAH74139.1| 3548|Homo sapiens sushi, von Willebrand f... 66 7e-11 AL158158-3|CAI14068.1| 3548|Homo sapiens sushi, von Willebrand f... 66 7e-11 AL132767-2|CAM28320.1| 594|Homo sapiens EGF-like-domain, multip... 66 7e-11 AL132767-1|CAI22904.1| 619|Homo sapiens EGF-like-domain, multip... 66 7e-11 AL109612-2|CAM27006.1| 594|Homo sapiens EGF-like-domain, multip... 66 7e-11 AL109612-1|CAI18881.1| 619|Homo sapiens EGF-like-domain, multip... 66 7e-11 AK027870-1|BAB55420.1| 1316|Homo sapiens protein ( Homo sapiens ... 66 7e-11 AJ619977-1|CAF04067.1| 3574|Homo sapiens SEL-OB protein protein. 66 7e-11 AF279305-1|AAF81912.1| 653|Homo sapiens delta 4 protein. 66 7e-11 AF253468-1|AAF76427.1| 685|Homo sapiens notch ligand DLL4 protein. 66 7e-11 AB043894-1|BAB18581.1| 685|Homo sapiens Delta-4 protein. 66 7e-11 AB036931-1|BAB16085.1| 685|Homo sapiens notch ligand delta-2 pr... 66 7e-11 U95299-1|AAC32288.1| 2003|Homo sapiens Notch4 protein. 66 1e-10 M73980-1|AAA60614.1| 2444|Homo sapiens TAN1 protein. 66 1e-10 D86566-1|BAA13116.1| 955|Homo sapiens notch related protein pro... 66 1e-10 BX284927-1|CAM25850.1| 2003|Homo sapiens Notch homolog 4 (Drosop... 66 1e-10 BX284686-1|CAM26209.1| 2003|Homo sapiens Notch homolog 4 (Drosop... 66 1e-10 BC063815-1|AAH63815.1| 647|Homo sapiens NOTCH4 protein protein. 66 1e-10 AL845509-1|CAI18564.1| 2003|Homo sapiens Notch homolog 4 (Drosop... 66 1e-10 AL845464-12|CAI41803.1| 2003|Homo sapiens Notch homolog 4 (Droso... 66 1e-10 AL662884-27|CAI18362.1| 2003|Homo sapiens Notch homolog 4 (Droso... 66 1e-10 AF308602-1|AAG33848.1| 2556|Homo sapiens NOTCH 1 protein. 66 1e-10 AK074062-1|BAB84888.1| 1282|Homo sapiens FLJ00133 protein protein. 65 2e-10 AF439717-1|AAQ04558.1| 1008|Homo sapiens insulin responsive sequ... 65 2e-10 U70312-1|AAC02648.1| 480|Homo sapiens integrin binding protein ... 64 2e-10 BC030828-1|AAH30828.1| 480|Homo sapiens EGF-like repeats and di... 64 2e-10 U89335-1|AAC63097.1| 1999|Homo sapiens notch4 protein. 64 3e-10 U26555-1|AAA67565.1| 1642|Homo sapiens versican V2 core protein ... 64 3e-10 AL662830-9|CAI17543.1| 2005|Homo sapiens Notch homolog 4 (Drosop... 64 3e-10 AB023961-1|BAB20317.1| 502|Homo sapiens notch4 protein. 64 3e-10 AL513325-3|CAM17208.1| 1294|Homo sapiens crumbs homolog 1 (Droso... 64 4e-10 AL139136-3|CAM21656.1| 1294|Homo sapiens crumbs homolog 1 (Droso... 64 4e-10 AL136322-4|CAM23328.1| 1294|Homo sapiens crumbs homolog 1 (Droso... 64 4e-10 AJ748821-1|CAG38658.1| 1294|Homo sapiens crumbs homologue 1 (alt... 64 4e-10 U77914-1|AAC50909.1| 263|Homo sapiens soluble protein Jagged pr... 63 5e-10 X15998-1|CAA34128.1| 2409|Homo sapiens protein ( H.sapiens mRNA ... 63 7e-10 U77493-1|AAB19224.1| 263|Homo sapiens Notch2 protein. 63 7e-10 U16306-1|AAA65018.1| 3396|Homo sapiens chondroitin sulfate prote... 63 7e-10 J02814-1|AAA36437.1| 688|Homo sapiens protein ( Human chondroit... 63 7e-10 D32039-1|BAA06801.1| 655|Homo sapiens proteoglycan PG-M(V3) pro... 63 7e-10 BX641036-1|CAE46022.1| 2060|Homo sapiens hypothetical protein pr... 63 7e-10 AB209491-1|BAD92728.1| 3410|Homo sapiens chondroitin sulfate pro... 63 7e-10 S83182-1|AAB46909.1| 560|Homo sapiens hyaluronan-binding protei... 62 2e-09 D49742-1|BAA08576.1| 560|Homo sapiens HGF activator like protei... 62 2e-09 BC031412-1|AAH31412.1| 560|Homo sapiens hyaluronan binding prot... 62 2e-09 AY534754-1|AAS16352.1| 560|Homo sapiens hyaluronan binding prot... 62 2e-09 AL390197-1|CAH71108.1| 560|Homo sapiens hyaluronan binding prot... 62 2e-09 Y14330-1|CAA74706.1| 1223|Homo sapiens jagged2 protein protein. 61 2e-09 AF111170-2|AAD15562.1| 1238|Homo sapiens Jagged2 protein. 61 2e-09 AF029779-1|AAB84216.1| 1200|Homo sapiens hJAG2.del-E6 protein. 61 2e-09 AF029778-1|AAB84215.1| 1238|Homo sapiens Jagged2 protein. 61 2e-09 AF020201-1|AAB71189.1| 1238|Homo sapiens Jagged 2 protein. 61 2e-09 AF003521-1|AAB61285.1| 1238|Homo sapiens Jagged 2 protein. 61 2e-09 BC053656-1|AAH53656.1| 470|Homo sapiens EDIL3 protein protein. 61 3e-09 BC035009-1|AAH35009.1| 737|Homo sapiens delta/notch-like EGF re... 60 4e-09 BC024766-1|AAH24766.2| 454|Homo sapiens DNER protein protein. 60 4e-09 AY720432-1|AAU14134.1| 1285|Homo sapiens crumbs-like protein 2 p... 60 4e-09 AY358891-1|AAQ89250.1| 737|Homo sapiens QPRR262 protein. 60 4e-09 AL445489-4|CAI39793.1| 1285|Homo sapiens crumbs homolog 2 (Droso... 60 4e-09 AL445489-3|CAM14433.1| 1176|Homo sapiens crumbs homolog 2 (Droso... 60 4e-09 AL365504-3|CAI41011.1| 1285|Homo sapiens crumbs homolog 2 (Droso... 60 4e-09 AL365504-2|CAM21391.1| 1176|Homo sapiens crumbs homolog 2 (Droso... 60 4e-09 AK123000-1|BAC85516.1| 1176|Homo sapiens 3 (HIVEP3). protein. 60 4e-09 AF442487-1|AAM21557.1| 737|Homo sapiens delta-notch-like EGF re... 60 4e-09 AF051345-1|AAC39880.2| 1624|Homo sapiens latent transforming gro... 60 4e-09 AF051344-1|AAC39879.2| 1557|Homo sapiens latent transforming gro... 60 4e-09 AC008273-1|AAF19247.2| 291|Homo sapiens unknown protein. 60 4e-09 BC000218-1|AAH00218.1| 618|Homo sapiens delta-like 3 (Drosophil... 60 5e-09 AF241373-1|AAF62542.1| 618|Homo sapiens DLL3 protein precursor ... 60 5e-09 D63395-1|BAA09708.1| 1095|Homo sapiens notch related protein pro... 60 6e-09 AK075302-1|BAC11535.1| 587|Homo sapiens protein ( Homo sapiens ... 60 6e-09 Y13622-1|CAA73944.1| 1587|Homo sapiens latent TGF-beta binding p... 59 8e-09 BX640729-1|CAE45845.1| 674|Homo sapiens hypothetical protein pr... 59 1e-08 AL136322-1|CAI16644.1| 674|Homo sapiens crumbs homolog 1 (Droso... 59 1e-08 AK126775-1|BAC86684.1| 952|Homo sapiens protein ( Homo sapiens ... 59 1e-08 AB033063-1|BAA86551.2| 1268|Homo sapiens KIAA1237 protein protein. 59 1e-08 BC063822-1|AAH63822.1| 1009|Homo sapiens EGF-like, fibronectin t... 58 1e-08 AK097549-1|BAC05096.1| 775|Homo sapiens protein ( Homo sapiens ... 58 1e-08 Z12172-1|CAA78163.1| 383|Homo sapiens putative homeotic protein... 58 2e-08 U15981-1|AAA75365.1| 310|Homo sapiens dlk protein. 58 2e-08 U15979-1|AAA75364.1| 382|Homo sapiens dlk protein. 58 2e-08 DQ309460-1|ABC26875.1| 231|Homo sapiens delta-like 1 protein. 58 2e-08 DQ126100-1|AAZ38943.1| 212|Homo sapiens brevideltin protein. 58 2e-08 DQ017081-1|AAY40461.1| 315|Homo sapiens secredeltin protein. 58 2e-08 BC014015-1|AAH14015.1| 383|Homo sapiens delta-like 1 homolog (D... 58 2e-08 BC013197-1|AAH13197.1| 383|Homo sapiens delta-like 1 homolog (D... 58 2e-08 BC007741-1|AAH07741.1| 383|Homo sapiens delta-like 1 homolog (D... 58 2e-08 AL137311-1|CAB70690.1| 252|Homo sapiens hypothetical protein pr... 58 2e-08 AY714129-1|AAU94938.1| 4186|Homo sapiens anchor protein protein. 57 3e-08 AL450324-2|CAI13283.1| 186|Homo sapiens protein ( Human DNA seq... 57 3e-08 AF231023-1|AAF61929.1| 3312|Homo sapiens protocadherin Flamingo ... 57 3e-08 AB024578-1|BAA88952.1| 78|Homo sapiens notch4 protein. 57 3e-08 BX537434-1|CAD97676.1| 236|Homo sapiens hypothetical protein pr... 56 8e-08 BC090943-1|AAH90943.1| 249|Homo sapiens NOTCH2NL protein protein. 56 8e-08 BC084572-1|AAH84572.1| 343|Homo sapiens NOTCH2NL protein protein. 56 8e-08 BC065219-1|AAH65219.2| 236|Homo sapiens Notch homolog 2 (Drosop... 56 8e-08 BC019835-1|AAH19835.1| 236|Homo sapiens Notch homolog 2 N-termi... 56 8e-08 BC010154-1|AAH10154.3| 236|Homo sapiens Notch homolog 2 (Drosop... 56 8e-08 AY165865-1|AAO18147.1| 2809|Homo sapiens fibrillin-3 short form ... 56 8e-08 AY165864-1|AAO18146.1| 2809|Homo sapiens fibrillin-3 short form ... 56 8e-08 AY165863-1|AAO18145.1| 2809|Homo sapiens fibrillin-3 short form ... 56 8e-08 AL592307-2|CAH73994.1| 230|Homo sapiens Notch homolog 2 (Drosop... 56 8e-08 AL592307-1|CAH73993.1| 236|Homo sapiens Notch homolog 2 (Drosop... 56 8e-08 AK075065-1|BAC11381.1| 269|Homo sapiens protein ( Homo sapiens ... 56 8e-08 AB177800-1|BAD16736.1| 2809|Homo sapiens fibrillin 3 protein. 56 8e-08 AB177799-1|BAD16735.1| 2809|Homo sapiens fibrillin 3 protein. 56 8e-08 AB177798-1|BAD16734.1| 2809|Homo sapiens fibrillin 3 protein. 56 8e-08 AB177797-1|BAD16733.1| 2809|Homo sapiens fibrillin 3 protein. 56 8e-08 AB053450-1|BAB47408.2| 2816|Homo sapiens fibrillin3 protein. 56 8e-08 X63556-1|CAA45118.1| 3002|Homo sapiens fibrillin protein. 56 1e-07 M59303-1|AAA36499.1| 320|Homo sapiens protein Z protein. 56 1e-07 M55671-1|AAA36501.1| 422|Homo sapiens protein Z protein. 56 1e-07 M55670-1|AAA36500.1| 400|Homo sapiens protein Z protein. 56 1e-07 L13923-1|AAB02036.1| 2871|Homo sapiens fibrillin protein. 56 1e-07 BC126986-1|AAI26987.1| 393|Homo sapiens FLJ37440 protein protein. 56 1e-07 BC074907-1|AAH74907.1| 400|Homo sapiens protein Z, vitamin K-de... 56 1e-07 BC074906-1|AAH74906.1| 400|Homo sapiens protein Z, vitamin K-de... 56 1e-07 AL137002-16|CAI41388.1| 400|Homo sapiens protein Z, vitamin K-d... 56 1e-07 AL137002-15|CAI41389.1| 422|Homo sapiens protein Z, vitamin K-d... 56 1e-07 AF440358-1|AAL27631.1| 400|Homo sapiens protein Z, vitamin K-de... 56 1e-07 AB177803-1|BAD16739.1| 2871|Homo sapiens fibrillin 1 protein. 56 1e-07 AB177802-1|BAD16738.1| 1365|Homo sapiens fibrillin 1 protein. 56 1e-07 AB033749-2|BAA85764.1| 422|Homo sapiens protein Z spliced varia... 56 1e-07 AB033749-1|BAA85763.1| 400|Homo sapiens protein Z protein. 56 1e-07 X87241-1|CAA60685.1| 4590|Homo sapiens homologue of Drosophila F... 55 1e-07 AB208840-1|BAD92077.1| 830|Homo sapiens fibrillin 1 variant pro... 55 1e-07 BC027939-1|AAH27939.1| 600|Homo sapiens SNED1 protein protein. 54 2e-07 AK074075-1|BAB84901.1| 522|Homo sapiens FLJ00146 protein protein. 54 2e-07 U03272-1|AAA18950.1| 2911|Homo sapiens fibrillin-2 protein. 54 4e-07 D87469-1|BAA13407.2| 2854|Homo sapiens KIAA0279 protein protein. 54 4e-07 AY356402-1|AAR13653.1| 3222|Homo sapiens fat-like cadherin FATJ ... 54 4e-07 AL390252-1|CAI13170.1| 2923|Homo sapiens cadherin, EGF LAG seven... 54 4e-07 AF234887-1|AAG00080.1| 2923|Homo sapiens FLAMINGO 1 protein. 54 4e-07 AB065955-1|BAC06168.1| 2923|Homo sapiens seven transmembrane hel... 54 4e-07 AL731551-1|CAI40246.1| 3623|Homo sapiens cubilin (intrinsic fact... 53 6e-07 AL596445-1|CAH72450.1| 3623|Homo sapiens cubilin (intrinsic fact... 53 6e-07 AL365215-1|CAH73630.1| 3623|Homo sapiens cubilin (intrinsic fact... 53 6e-07 AF243129-1|AAK61830.1| 3494|Homo sapiens intrinsic factor-vitami... 53 6e-07 AF034611-1|AAC82612.1| 3623|Homo sapiens intrinsic factor-B12 re... 53 6e-07 L38969-1|AAC41762.1| 956|Homo sapiens thrombospondin 3 protein. 52 1e-06 BC113847-1|AAI13848.1| 956|Homo sapiens thrombospondin 3, precu... 52 1e-06 AL713999-15|CAI95084.1| 956|Homo sapiens thrombospondin 3 protein. 52 1e-06 AK223278-1|BAD96998.1| 956|Homo sapiens thrombospondin 3 precur... 52 1e-06 AF023268-6|AAC51818.1| 736|Homo sapiens thrombospondin3 protein. 52 1e-06 AB076400-1|BAB86868.1| 1097|Homo sapiens fat3 protein. 52 1e-06 M34057-1|AAA61160.1| 1394|Homo sapiens TGFB1 protein. 52 2e-06 BC130289-1|AAI30290.1| 1395|Homo sapiens latent transforming gro... 52 2e-06 AF489528-1|AAM03124.1| 1394|Homo sapiens transforming growth fac... 52 2e-06 AF026547-1|AAC80576.1| 1321|Homo sapiens neurocan protein. 52 2e-06 AC019127-1|AAY24260.1| 697|Homo sapiens unknown protein. 52 2e-06 AC005254-1|AAC25581.1| 315|Homo sapiens PGCN_HUMAN, PARTIAL CDS... 52 2e-06 AB210004-1|BAE06086.1| 1335|Homo sapiens CSPG3 variant protein p... 52 2e-06 AB208801-1|BAD92038.1| 1348|Homo sapiens latent transforming gro... 52 2e-06 U70313-1|AAC02649.1| 125|Homo sapiens integrin binding protein ... 51 2e-06 EF539882-1|ABS86974.1| 1547|Homo sapiens NRXN1-alpha protein. 51 2e-06 BC150247-1|AAI50248.1| 1496|Homo sapiens NRXN1 protein protein. 51 2e-06 BC110320-1|AAI10321.1| 383|Homo sapiens delta-like 2 homolog (D... 51 2e-06 AY358126-1|AAQ88493.1| 383|Homo sapiens PSGC2903 protein. 51 2e-06 AL359813-9|CAI23224.1| 383|Homo sapiens EGF-like-domain, multip... 51 2e-06 AL359813-8|CAI23223.1| 377|Homo sapiens EGF-like-domain, multip... 51 2e-06 AL359813-6|CAI23221.1| 288|Homo sapiens EGF-like-domain, multip... 51 2e-06 AK074396-1|BAB85069.1| 220|Homo sapiens protein ( Homo sapiens ... 51 2e-06 AC007462-1|AAF03536.1| 681|Homo sapiens unknown protein. 51 2e-06 AB035356-1|BAA87821.1| 1477|Homo sapiens neurexin I-alpha protei... 51 2e-06 AB011150-1|BAA25504.2| 1542|Homo sapiens KIAA0578 protein protein. 51 2e-06 Z37976-1|CAA86030.1| 1821|Homo sapiens LTBP-2 precursor protein. 51 3e-06 S82451-1|AAB37459.1| 1821|Homo sapiens latent transforming growt... 51 3e-06 BC078659-1|AAH78659.1| 1821|Homo sapiens latent transforming gro... 51 3e-06 AB209865-1|BAD93102.1| 1700|Homo sapiens latent transforming gro... 51 3e-06 U33837-1|AAB41649.1| 4655|Homo sapiens gp330 precursor protein. 50 4e-06 U04441-1|AAB02882.1| 1751|Homo sapiens glycoprotein 330 protein. 50 4e-06 AY265358-1|AAP88586.1| 4655|Homo sapiens glycoprotein receptor g... 50 4e-06 AY265357-1|AAP88585.1| 4655|Homo sapiens glycoprotein receptor g... 50 4e-06 AC007556-2|AAX88965.1| 3881|Homo sapiens unknown protein. 50 4e-06 DQ138965-1|AAZ66768.1| 203|Homo sapiens truncated brevideltinin... 50 5e-06 Z85995-1|CAI42721.1| 2725|Homo sapiens odz, odd Oz/ten-m homolog... 50 7e-06 Z83823-1|CAI42742.1| 2725|Homo sapiens odz, odd Oz/ten-m homolog... 50 7e-06 Z81008-1|CAI42710.1| 2725|Homo sapiens odz, odd Oz/ten-m homolog... 50 7e-06 BC006425-1|AAH06425.1| 204|Homo sapiens EGFL9 protein protein. 50 7e-06 BC000230-1|AAH00230.1| 204|Homo sapiens EGFL9 protein protein. 50 7e-06 AL031075-1|CAI43065.1| 2725|Homo sapiens odz, odd Oz/ten-m homol... 50 7e-06 AL023878-1|CAI42975.1| 2725|Homo sapiens odz, odd Oz/ten-m homol... 50 7e-06 AL022718-3|CAI42154.1| 2725|Homo sapiens odz, odd Oz/ten-m homol... 50 7e-06 AF100772-1|AAF04723.1| 2725|Homo sapiens tenascin-M1 protein. 50 7e-06 U89336-6|AAB47494.1| 293|Homo sapiens NG3 protein. 49 9e-06 BX284686-12|CAM26220.1| 293|Homo sapiens EGF-like-domain, multi... 49 9e-06 BC150275-1|AAI50276.1| 1642|Homo sapiens neurexin 2 protein. 49 9e-06 BC052591-1|AAH52591.1| 293|Homo sapiens EGF-like-domain, multip... 49 9e-06 BC035574-1|AAH35574.1| 293|Homo sapiens EGF-like-domain, multip... 49 9e-06 BC031251-1|AAH31251.1| 375|Homo sapiens EGF-like, fibronectin t... 49 9e-06 AY358139-1|AAQ88506.1| 293|Homo sapiens NG3 protein. 49 9e-06 AL845464-11|CAI41800.2| 293|Homo sapiens EGF-like-domain, multi... 49 9e-06 AL662884-17|CAI18345.2| 293|Homo sapiens EGF-like-domain, multi... 49 9e-06 AL662828-17|CAI17428.1| 293|Homo sapiens EGF-like-domain, multi... 49 9e-06 AL031597-2|CAI23555.1| 3014|Homo sapiens cadherin, EGF LAG seven... 49 9e-06 AL031588-3|CAI19319.1| 3014|Homo sapiens cadherin, EGF LAG seven... 49 9e-06 AL021392-2|CAI20967.1| 3014|Homo sapiens cadherin, EGF LAG seven... 49 9e-06 AK092479-1|BAC03900.1| 463|Homo sapiens protein ( Homo sapiens ... 49 9e-06 AF231024-1|AAF61930.1| 3014|Homo sapiens protocadherin Flamingo ... 49 9e-06 AC044790-1|AAK68154.1| 1712|Homo sapiens NRXN2 protein. 49 9e-06 AB209735-1|BAD92972.1| 1976|Homo sapiens fibrillin 2 (congenital... 49 9e-06 AB190520-1|BAD51398.1| 293|Homo sapiens VE-statin2 protein. 49 9e-06 AB177862-1|BAD66840.1| 1434|Homo sapiens KIAA0921 splice variant... 49 9e-06 AB035266-1|BAA94075.1| 1712|Homo sapiens neurexin II protein. 49 9e-06 AB023138-1|BAA76765.2| 1658|Homo sapiens KIAA0921 protein protein. 49 9e-06 AL137007-1|CAC10575.2| 199|Homo sapiens novel EGF-like domain c... 49 1e-05 X60957-1|CAA43290.1| 1138|Homo sapiens receptor tyrosine kinase ... 48 2e-05 BC038239-1|AAH38239.1| 1138|Homo sapiens tyrosine kinase with im... 48 2e-05 AL356104-4|CAH72941.1| 1037|Homo sapiens novel protein similar t... 48 2e-05 AL355357-1|CAI16435.1| 95|Homo sapiens protein ( Human DNA seq... 48 2e-05 AL158169-5|CAH70011.1| 1037|Homo sapiens novel protein similar t... 48 2e-05 AL139289-10|CAI23385.1| 1138|Homo sapiens tyrosine kinase with i... 48 2e-05 AK074121-1|BAB84947.1| 491|Homo sapiens FLJ00193 protein protein. 48 2e-05 AJ316284-1|CAC87720.2| 1392|Homo sapiens neurexin 3-alpha protein. 48 2e-05 AC009396-1|AAF21147.1| 351|Homo sapiens neurexin III protein. 48 2e-05 AB018286-1|BAA34463.2| 1205|Homo sapiens KIAA0743 protein protein. 48 2e-05 BC027971-1|AAH27971.1| 911|Homo sapiens brevican protein. 48 3e-05 BC022938-1|AAH22938.1| 911|Homo sapiens brevican protein. 48 3e-05 BC018037-1|AAH18037.1| 379|Homo sapiens WNT inhibitory factor 1... 48 3e-05 BC010571-1|AAH10571.1| 911|Homo sapiens brevican protein. 48 3e-05 BC009117-1|AAH09117.1| 911|Homo sapiens brevican protein. 48 3e-05 AY358372-1|AAQ88738.1| 911|Homo sapiens Brevican Core Pro protein. 48 3e-05 AY358344-1|AAQ88710.1| 379|Homo sapiens WIF-1 protein. 48 3e-05 AL590666-18|CAI16352.1| 911|Homo sapiens brevican protein. 48 3e-05 AL365181-12|CAI13056.1| 911|Homo sapiens brevican protein. 48 3e-05 AL137504-1|CAB70776.1| 330|Homo sapiens hypothetical protein pr... 48 3e-05 AF228710-1|AAG23134.1| 911|Homo sapiens chondroitin sulfate pro... 48 3e-05 AF122922-1|AAD25402.1| 379|Homo sapiens Wnt inhibitory factor-1... 48 3e-05 AB209570-1|BAD92807.1| 850|Homo sapiens brevican isoform 1 vari... 48 3e-05 L06139-1|AAA61139.1| 1124|Homo sapiens receptor protein-tyrosine... 47 4e-05 BC035514-1|AAH35514.2| 1124|Homo sapiens TEK tyrosine kinase, en... 47 4e-05 AL133411-1|CAI16055.1| 1124|Homo sapiens TEK tyrosine kinase, en... 47 4e-05 AK027618-1|BAB55237.1| 849|Homo sapiens protein ( Homo sapiens ... 47 4e-05 AB208796-1|BAD92033.1| 1157|Homo sapiens TEK tyrosine kinase var... 47 4e-05 AB086825-1|BAC45250.1| 788|Homo sapiens receptor protein tyrosi... 47 4e-05 AB040888-1|BAA95979.2| 2450|Homo sapiens KIAA1455 protein protein. 47 4e-05 AF054502-1|AAC39882.1| 669|Homo sapiens latent transforming gro... 46 6e-05 AC013451-1|AAF87081.1| 969|Homo sapiens LTBP-2 protein. 46 6e-05 X71923-1|CAA50739.1| 750|Homo sapiens tenascin-X precursor prot... 46 8e-05 U89337-3|AAB47488.1| 4289|Homo sapiens tenascin X protein. 46 8e-05 AL772248-1|CAI18078.1| 4222|Homo sapiens tenascin XB protein. 46 8e-05 AL662884-1|CAI18332.1| 4222|Homo sapiens tenascin XB protein. 46 8e-05 AL662849-16|CAI17471.1| 4222|Homo sapiens tenascin XB protein. 46 8e-05 AL662828-1|CAI17414.1| 4222|Homo sapiens tenascin XB protein. 46 8e-05 AL645922-1|CAI41718.1| 4222|Homo sapiens tenascin XB protein. 46 8e-05 AL049547-2|CAB89296.1| 4288|Homo sapiens dJ34F7.1.1 (tenascin XB... 46 8e-05 X62009-1|CAB56757.1| 754|Homo sapiens fibrillin 5 protein. 46 1e-04 AB037723-1|BAA92540.3| 2016|Homo sapiens KIAA1302 protein protein. 46 1e-04 L20470-1|AAA53684.1| 873|Homo sapiens very low density lipoprot... 45 1e-04 L00352-1|AAA56833.1| 860|Homo sapiens low density lipoprotein r... 45 1e-04 BT007361-1|AAP36025.1| 860|Homo sapiens low density lipoprotein... 45 1e-04 BC014514-1|AAH14514.1| 860|Homo sapiens low density lipoprotein... 45 1e-04 BC008761-1|AAH08761.2| 743|Homo sapiens LTBP3 protein protein. 45 1e-04 AY324609-1|AAP72971.1| 860|Homo sapiens low density lipoprotein... 45 1e-04 AY114155-1|AAM56036.1| 860|Homo sapiens low density lipoprotein... 45 1e-04 AK024477-1|BAB15767.1| 1382|Homo sapiens FLJ00070 protein protein. 45 1e-04 AF217403-1|AAF24515.1| 837|Homo sapiens low density lipoprotein... 45 1e-04 AF135960-1|AAF62352.3| 1256|Homo sapiens latent transforming gro... 45 1e-04 AB209409-1|BAD92646.1| 870|Homo sapiens low density lipoprotein... 45 1e-04 X82245-1|CAA57709.1| 1246|Homo sapiens nidogen protein. 45 2e-04 X62008-1|CAB56534.1| 517|Homo sapiens fibrillin 15 protein. 45 2e-04 M30269-1|AAA59932.1| 1247|Homo sapiens nidogen protein. 45 2e-04 M27445-1|AAA57261.1| 581|Homo sapiens nidogen protein. 45 2e-04 D87433-1|BAA13377.2| 2589|Homo sapiens KIAA0246 protein protein. 45 2e-04 DQ786774-1|ABG91068.1| 2570|Homo sapiens FEX1 protein. 45 2e-04 BC150250-1|AAI50251.1| 2570|Homo sapiens stabilin 1 protein. 45 2e-04 AL139161-2|CAI23422.1| 1247|Homo sapiens nidogen 1 protein. 45 2e-04 AL122018-2|CAI22681.1| 1247|Homo sapiens nidogen 1 protein. 45 2e-04 AJ275213-1|CAB61827.1| 2570|Homo sapiens stabilin-1 protein. 45 2e-04 AB052956-1|BAC15606.1| 2570|Homo sapiens FELE-1 protein. 45 2e-04 S73849-1|AAB31735.1| 873|Homo sapiens very low density lipoprot... 44 3e-04 L22431-1|AAA61344.1| 873|Homo sapiens very low density lipoprot... 44 3e-04 D16532-1|BAA03969.1| 873|Homo sapiens very low density lipoprot... 44 3e-04 D16494-1|BAA03946.1| 845|Homo sapiens very low density lipoprot... 44 3e-04 D16493-1|BAA03945.1| 873|Homo sapiens very low density lipoprot... 44 3e-04 DQ067198-1|AAY46157.1| 873|Homo sapiens very low density lipopr... 44 3e-04 BC142653-1|AAI42654.1| 845|Homo sapiens very low density lipopr... 44 3e-04 AL450467-4|CAH72453.1| 752|Homo sapiens very low density lipopr... 44 3e-04 AL450467-3|CAH72455.1| 845|Homo sapiens very low density lipopr... 44 3e-04 AL450467-2|CAH72454.1| 873|Homo sapiens very low density lipopr... 44 3e-04 AL117551-1|CAB55988.1| 511|Homo sapiens hypothetical protein pr... 44 3e-04 AK092381-1|BAC03874.1| 752|Homo sapiens protein ( Homo sapiens ... 44 3e-04 AB209448-1|BAD92685.1| 1241|Homo sapiens nidogen (enactin) varia... 44 3e-04 AB208822-1|BAD92059.1| 555|Homo sapiens Very low-density lipopr... 44 3e-04 X58531-1|CAA41418.1| 2628|Homo sapiens laminin A chain protein. 44 3e-04 AY311388-1|AAP74958.1| 2551|Homo sapiens FEX2 protein. 44 3e-04 AY227444-1|AAO39681.1| 1416|Homo sapiens hyaluronan receptor for... 44 3e-04 AK160380-1|BAD18723.1| 1055|Homo sapiens FLJ00344 protein protein. 44 3e-04 AK074051-1|BAB84877.1| 1736|Homo sapiens FLJ00122 protein protein. 44 3e-04 AK024503-1|BAB15793.1| 1192|Homo sapiens FLJ00112 protein protein. 44 3e-04 AJ295695-1|CAC82105.1| 2551|Homo sapiens stabilin-2 protein. 44 3e-04 AF160476-1|AAF82398.1| 897|Homo sapiens CD44-like precursor FEL... 44 3e-04 AC026888-1|AAF87841.1| 328|Homo sapiens NRXNIII protein. 44 3e-04 AC019195-1|AAY14953.1| 546|Homo sapiens unknown protein. 44 3e-04 AB231860-1|BAE19678.1| 1640|Homo sapiens hypothetical protein pr... 44 3e-04 AB052958-1|BAC15608.1| 2551|Homo sapiens FELE-2 protein. 44 3e-04 AB032953-1|BAA86441.2| 2144|Homo sapiens KIAA1127 protein protein. 44 3e-04 M35672-1|AAA51981.1| 291|Homo sapiens F9 protein. 43 6e-04 M11309-1|AAA52023.1| 461|Homo sapiens F9 protein. 43 6e-04 K02402-1|AAB59620.1| 461|Homo sapiens factor IX protein. 43 6e-04 K02053-1|AAA56822.1| 461|Homo sapiens protein ( Human factor IX... 43 6e-04 J00137-1|AAA52763.1| 461|Homo sapiens F9 protein. 43 6e-04 J00136-1|AAA98726.1| 462|Homo sapiens factor IX protein. 43 6e-04 D89629-1|BAB46925.1| 815|Homo sapiens cerebral protein-12 protein. 43 6e-04 D83018-1|BAA11681.1| 816|Homo sapiens nel-related protein 2 pro... 43 6e-04 BC109215-1|AAI09216.1| 461|Homo sapiens F9 protein protein. 43 6e-04 BC109214-1|AAI09215.1| 461|Homo sapiens F9 protein protein. 43 6e-04 BC068575-1|AAH68575.1| 673|Homo sapiens vasorin protein. 43 6e-04 BC020544-1|AAH20544.1| 816|Homo sapiens NELL2 protein protein. 43 6e-04 BC013767-1|AAH13767.1| 601|Homo sapiens VASN protein protein. 43 6e-04 AY358299-1|AAQ88666.1| 673|Homo sapiens CSRV314 protein. 43 6e-04 AY358298-1|AAQ88665.1| 598|Homo sapiens CSRV314 protein. 43 6e-04 AY166584-1|AAO27704.1| 673|Homo sapiens vasorin protein. 43 6e-04 AL033403-1|CAI42103.1| 461|Homo sapiens coagulation factor IX (... 43 6e-04 AF536327-1|AAM96188.1| 461|Homo sapiens coagulation factor IX (... 43 6e-04 AK131282-1|BAD18457.1| 872|Homo sapiens protein ( Homo sapiens ... 42 0.001 U57523-1|AAB06946.1| 446|Homo sapiens protein ( Human nel homol... 42 0.001 D83017-1|BAA11680.1| 810|Homo sapiens nel-related protein protein. 42 0.001 BC096103-1|AAH96103.1| 763|Homo sapiens NELL1 protein protein. 42 0.001 BC096102-1|AAH96102.1| 810|Homo sapiens NEL-like 1 (chicken) pr... 42 0.001 BC096101-1|AAH96101.1| 810|Homo sapiens NEL-like 1 (chicken) pr... 42 0.001 BC096100-1|AAH96100.1| 763|Homo sapiens NELL1 protein protein. 42 0.001 BC069674-1|AAH69674.1| 810|Homo sapiens nel-like 1, precursor p... 42 0.001 BC034009-1|AAH34009.1| 181|Homo sapiens AGRN protein protein. 42 0.001 BC004220-1|AAH04220.2| 116|Homo sapiens AGRN protein protein. 42 0.001 AF283408-1|AAL38109.1| 1537|Homo sapiens candidate tumor suppres... 42 0.001 AF187072-1|AAF08273.1| 515|Homo sapiens N-acetylglucosamine-1-p... 42 0.001 AF176832-1|AAF70379.1| 4599|Homo sapiens low density lipoprotein... 42 0.001 AC068195-1|AAX93243.1| 1126|Homo sapiens unknown protein. 42 0.001 AB209707-1|BAD92944.1| 1720|Homo sapiens low density lipoprotein... 42 0.001 M17778-1|AAA36799.1| 640|Homo sapiens protein ( Human uromoduli... 42 0.002 M15881-1|AAA36798.1| 640|Homo sapiens protein ( Human uromoduli... 42 0.002 BC038242-1|AAH38242.1| 261|Homo sapiens Similar to RIKEN cDNA 1... 42 0.002 BC035975-1|AAH35975.1| 611|Homo sapiens UMOD protein protein. 42 0.002 BC035784-1|AAH35784.1| 439|Homo sapiens hypothetical protein FL... 42 0.002 AY162970-1|AAO64446.1| 640|Homo sapiens uromodulin precursor pr... 42 0.002 AK094759-1|BAC04416.1| 439|Homo sapiens protein ( Homo sapiens ... 42 0.002 AC092645-2|AAY14854.1| 439|Homo sapiens unknown protein. 42 0.002 AB177801-1|BAD16737.1| 195|Homo sapiens fibrillin 1 protein. 42 0.002 Z99756-1|CAI18854.1| 988|Homo sapiens protein ( Human DNA seque... 41 0.002 Z82214-3|CAI21674.1| 988|Homo sapiens protein ( Human DNA seque... 41 0.002 AL513320-1|CAI14334.1| 1229|Homo sapiens multiple EGF-like-domai... 41 0.002 AL512413-3|CAH70834.1| 1229|Homo sapiens multiple EGF-like-domai... 41 0.002 AL133553-4|CAI17860.1| 240|Homo sapiens protein ( e PRG4 gene f... 41 0.002 AK027344-1|BAB55049.1| 741|Homo sapiens protein ( Homo sapiens ... 41 0.002 AJ291390-1|CAC19572.1| 901|Homo sapiens MUC3B mucin protein. 41 0.002 AB038783-1|BAB12117.1| 878|Homo sapiens intestinal mucin protein. 41 0.002 AB038781-1|BAB12115.1| 878|Homo sapiens intestinal mucin protein. 41 0.002 AB011539-1|BAA32467.2| 1246|Homo sapiens MEGF6 protein. 41 0.002 AB011536-1|BAA32464.1| 1364|Homo sapiens MEGF2 protein. 41 0.002 X13097-1|CAA31489.1| 291|Homo sapiens plasminogen activator pre... 41 0.003 X07393-1|CAA30302.1| 562|Homo sapiens protein ( Human fetal lun... 41 0.003 N00045-1|AAA52764.1| 488|Homo sapiens factor X precursor protein. 41 0.003 M57285-1|AAA52421.1| 488|Homo sapiens coagulation factor X prot... 41 0.003 M22613-1|AAA51984.1| 467|Homo sapiens F10 protein. 41 0.003 M18182-1|AAA36800.1| 562|Homo sapiens protein ( Human plasminog... 41 0.003 M15518-1|AAA60111.1| 562|Homo sapiens tissue-type plasminogen a... 41 0.003 L13720-1|AAA58494.1| 678|Homo sapiens growth-arrest-specific pr... 41 0.003 K03194-1|AAA52490.1| 476|Homo sapiens F10 protein. 41 0.003 K03021-1|AAA98809.1| 562|Homo sapiens plasminogen activator pro... 41 0.003 EF631974-1|ABR09277.1| 678|Homo sapiens growth arrest-specific ... 41 0.003 D01096-1|BAA00881.1| 532|Homo sapiens tissue plasminogen activa... 41 0.003 BX072579-3|CAH71174.1| 678|Homo sapiens growth arrest-specific ... 41 0.003 BT007060-1|AAP35709.1| 562|Homo sapiens plasminogen activator, ... 41 0.003 BC095403-1|AAH95403.1| 562|Homo sapiens plasminogen activator, ... 41 0.003 BC046125-1|AAH46125.1| 488|Homo sapiens coagulation factor X pr... 41 0.003 BC038984-1|AAH38984.1| 678|Homo sapiens growth arrest-specific ... 41 0.003 BC018636-1|AAH18636.3| 562|Homo sapiens plasminogen activator, ... 41 0.003 BC013968-1|AAH13968.3| 562|Homo sapiens plasminogen activator, ... 41 0.003 BC007231-1|AAH07231.1| 562|Homo sapiens plasminogen activator, ... 41 0.003 AY358336-1|AAQ88702.1| 509|Homo sapiens DFLL295 protein. 41 0.003 AY291060-1|AAP34246.1| 291|Homo sapiens plasminogen activator, ... 41 0.003 AY256843-1|AAO84057.1| 678|Homo sapiens growth arrested-specifi... 41 0.003 AY221101-1|AAO34406.1| 562|Homo sapiens tissue plasminogen acti... 41 0.003 AL137002-13|CAI41386.1| 488|Homo sapiens coagulation factor X p... 41 0.003 AL137002-12|CAI41385.1| 332|Homo sapiens coagulation factor X p... 41 0.003 AK126533-1|BAC86580.1| 624|Homo sapiens protein ( Homo sapiens ... 41 0.003 AF503510-1|AAM19347.1| 488|Homo sapiens coagulation factor X pr... 41 0.003 AF283412-1|AAL38110.1| 172|Homo sapiens candidate tumor suppres... 41 0.003 AF113616-1|AAF13032.1| 1217|Homo sapiens intestinal mucin 3 prot... 41 0.003 AF007194-1|AAC02272.1| 957|Homo sapiens mucin protein. 41 0.003 AC092156-1|AAY15024.1| 330|Homo sapiens unknown protein. 41 0.003 AB038784-1|BAB12118.1| 877|Homo sapiens intestinal mucin protein. 41 0.003 Y00692-1|CAA68687.1| 676|Homo sapiens preproprotein S protein. 40 0.004 X12892-1|CAA31383.1| 650|Homo sapiens protein ( H.sapiens mRNA ... 40 0.004 M57853-1|AAA60357.1| 676|Homo sapiens S protein protein. 40 0.004 M36564-1|AAA60180.1| 650|Homo sapiens PROS1 protein. 40 0.004 M15036-1|AAA36479.1| 676|Homo sapiens protein ( Human vitamin K... 40 0.004 M14338-1|AAA60181.1| 650|Homo sapiens protein S precursor protein. 40 0.004 M13232-2|AAA88041.1| 444|Homo sapiens protein ( Human factor VI... 40 0.004 M13232-1|AAA88040.1| 466|Homo sapiens coagulation factor VII pr... 40 0.004 J02933-1|AAA51983.1| 466|Homo sapiens protein ( Human blood coa... 40 0.004 DQ142911-1|ABD17891.1| 466|Homo sapiens cogulation factor VII p... 40 0.004 BC130468-1|AAI30469.1| 444|Homo sapiens coagulation factor VII ... 40 0.004 BC035608-1|AAH35608.1| 969|Homo sapiens NID2 protein protein. 40 0.004 BC015801-1|AAH15801.1| 676|Homo sapiens PROS1 protein protein. 40 0.004 BC002795-1|AAH02795.3| 516|Homo sapiens plasminogen activator, ... 40 0.004 AY308744-1|AAP45054.1| 497|Homo sapiens protein S (alpha) protein. 40 0.004 AY212252-1|AAP33841.1| 466|Homo sapiens FVII coagulation protei... 40 0.004 AL359813-7|CAI23222.1| 134|Homo sapiens EGF-like-domain, multip... 40 0.004 AL137002-10|CAI41381.1| 466|Homo sapiens coagulation factor VII... 40 0.004 AL137002-9|CAI41382.1| 444|Homo sapiens coagulation factor VII ... 40 0.004 AF466933-1|AAL66184.1| 466|Homo sapiens coagulation factor VII ... 40 0.004 AF272774-1|AAK58686.2| 679|Homo sapiens factor VII active site ... 40 0.004 X82494-1|CAA57876.1| 1184|Homo sapiens fibulin-2 protein. 40 0.006 X13916-1|CAA32112.1| 4544|Homo sapiens LDL-receptor related prec... 40 0.006 DQ314873-1|ABC40732.1| 4544|Homo sapiens low density lipoprotein... 40 0.006 BC088371-1|AAH88371.1| 273|Homo sapiens EGF-like-domain, multip... 40 0.006 BC051690-1|AAH51690.1| 1184|Homo sapiens fibulin 2 protein. 40 0.006 BC013770-1|AAH13770.1| 530|Homo sapiens netrin G2 protein. 40 0.006 BC012377-1|AAH12377.1| 273|Homo sapiens EGF-like-domain, multip... 40 0.006 AY358903-1|AAQ89262.1| 273|Homo sapiens VEMF protein. 40 0.006 AY358902-1|AAQ89261.1| 273|Homo sapiens VEMF protein. 40 0.006 AY358901-1|AAQ89260.1| 273|Homo sapiens VEMF protein. 40 0.006 AL590226-1|CAH71721.1| 273|Homo sapiens EGF-like-domain, multip... 40 0.006 AL353631-2|CAI16125.1| 530|Homo sapiens netrin G2 protein. 40 0.006 AL353631-1|CAI16126.1| 522|Homo sapiens netrin G2 protein. 40 0.006 AL159997-4|CAI40856.1| 530|Homo sapiens netrin G2 protein. 40 0.006 AL159997-3|CAI40855.1| 522|Homo sapiens netrin G2 protein. 40 0.006 AF186111-1|AAF01429.1| 273|Homo sapiens NOTCH4-like protein pro... 40 0.006 >X62515-1|CAA44373.1| 4393|Homo sapiens Human basement membrane heparan sulfate proteoglycan core protein protein. Length = 4393 Score = 101 bits (241), Expect = 2e-21 Identities = 59/173 (34%), Positives = 87/173 (50%), Gaps = 6/173 (3%) Frame = +2 Query: 14 PFIAESPDQWTVLELNQPLYIGGVPDFDQLPIDLAG-ASGFVGCISMLILGNEEKNIMAL 190 P S ++ L+LN+ LY+GG PD+ +P AG +SGF+GC+ L + EE L Sbjct: 3780 PVNGTSQGKFQGLDLNEELYLGGYPDYGAIP--KAGLSSGFIGCVRELRIQGEEIVFHDL 3837 Query: 191 ALEKENVQNCFTCAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRI-GESCRPGLCG 367 L + +C TC C N G C ++ YVC+C GF G+ C+ C P CG Sbjct: 3838 NLTAHGISHCPTCRDRPCQNGGQCHDS-ESSSYVCVCPAGFTGSRCEHSQALHCHPEACG 3896 Query: 368 P-GKCMNTAD--SYKCACPVTYTGKNCEVKQLIEYPAFTGS-A*LAIKPPTST 514 P C+N D Y C C + +G CE + P+ +G+ + LA+ T+T Sbjct: 3897 PDATCVNRPDGRGYTCRCHLGRSGLRCEEGVTVTTPSLSGAGSYLALPALTNT 3949 Score = 54.0 bits (124), Expect = 3e-07 Identities = 40/153 (26%), Positives = 66/153 (43%), Gaps = 7/153 (4%) Frame = +2 Query: 5 NSG-PFIAESPDQWTVLELNQPLYIGGVPDFDQLPIDLAGASGFVGCISMLILGNEEKNI 181 N G P + SP + L L+ LY+GGV L ++ F GC+ + + + ++ Sbjct: 4032 NGGRPVLRSSPGKSQGLNLHTLLYLGGVEPSVPLSPATNMSAHFRGCVGEVSVNGKRLDL 4091 Query: 182 MALALEKENVQNCFTCAP---NLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCR 352 L + + C+ +P C + C A E+ + CLC G G+ C+ C+ Sbjct: 4092 TYSFLGSQGIGQCYDSSPCERQPCQHGATCMPA-GEYEFQCLCRDGIKGDLCEHEENPCQ 4150 Query: 353 ---PGLCGPGKCMNTADSYKCACPVTYTGKNCE 442 P L G G C T +C C ++G C+ Sbjct: 4151 LREPCLHG-GTCQGT----RCLCLPGFSGPRCQ 4178 Score = 31.5 bits (68), Expect = 1.9 Identities = 20/61 (32%), Positives = 21/61 (34%) Frame = +2 Query: 239 LCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLCGPGKCMNTADSYKCACPV 418 LC NG E G C G C E C PG G D CACP+ Sbjct: 1564 LCECNGHSDLCHPETGACSQCQHNAAGEFC----ELCAPGYYGDATAGTPEDCQPCACPL 1619 Query: 419 T 421 T Sbjct: 1620 T 1620 Score = 31.5 bits (68), Expect = 1.9 Identities = 14/31 (45%), Positives = 16/31 (51%) Frame = +2 Query: 242 CLNNGVCQEALTEHGYVCLCAPGFGGNNCDR 334 CL+ G CQ G CLC PGF G C + Sbjct: 4155 CLHGGTCQ------GTRCLCLPGFSGPRCQQ 4179 >M85289-1|AAA52700.1| 4391|Homo sapiens heparan sulfate proteoglycan protein. Length = 4391 Score = 101 bits (241), Expect = 2e-21 Identities = 59/173 (34%), Positives = 87/173 (50%), Gaps = 6/173 (3%) Frame = +2 Query: 14 PFIAESPDQWTVLELNQPLYIGGVPDFDQLPIDLAG-ASGFVGCISMLILGNEEKNIMAL 190 P S ++ L+LN+ LY+GG PD+ +P AG +SGF+GC+ L + EE L Sbjct: 3778 PVNGTSQGKFQGLDLNEELYLGGYPDYGAIP--KAGLSSGFIGCVRELRIQGEEIVFHDL 3835 Query: 191 ALEKENVQNCFTCAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRI-GESCRPGLCG 367 L + +C TC C N G C ++ YVC+C GF G+ C+ C P CG Sbjct: 3836 NLTAHGISHCPTCRDRPCQNGGQCHDS-ESSSYVCVCPAGFTGSRCEHSQALHCHPEACG 3894 Query: 368 P-GKCMNTAD--SYKCACPVTYTGKNCEVKQLIEYPAFTGS-A*LAIKPPTST 514 P C+N D Y C C + +G CE + P+ +G+ + LA+ T+T Sbjct: 3895 PDATCVNRPDGRGYTCRCHLGRSGLRCEEGVTVTTPSLSGAGSYLALPALTNT 3947 Score = 56.4 bits (130), Expect = 6e-08 Identities = 41/153 (26%), Positives = 67/153 (43%), Gaps = 7/153 (4%) Frame = +2 Query: 5 NSG-PFIAESPDQWTVLELNQPLYIGGVPDFDQLPIDLAGASGFVGCISMLILGNEEKNI 181 N G P + SP + L L+ LY+GGV L ++ F GC+ + + + ++ Sbjct: 4030 NGGRPVLRSSPGKSQGLNLHTLLYLGGVEPSVPLSPATNMSAHFRGCVGEVSVNGKRLDL 4089 Query: 182 MALALEKENVQNCFTCAP---NLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCR 352 L + + C+ +P C + C A E+ + CLC GF G+ C+ C+ Sbjct: 4090 TYSFLGSQGIGQCYDSSPCERQPCQHGATCMPA-GEYEFQCLCRDGFKGDLCEHEENPCQ 4148 Query: 353 ---PGLCGPGKCMNTADSYKCACPVTYTGKNCE 442 P L G G C T +C C ++G C+ Sbjct: 4149 LREPCLHG-GTCQGT----RCLCLPGFSGPRCQ 4176 Score = 31.5 bits (68), Expect = 1.9 Identities = 20/61 (32%), Positives = 21/61 (34%) Frame = +2 Query: 239 LCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLCGPGKCMNTADSYKCACPV 418 LC NG E G C G C E C PG G D CACP+ Sbjct: 1562 LCECNGHSDLCHPETGACSQCQHNAAGEFC----ELCAPGYYGDATAGTPEDCQPCACPL 1617 Query: 419 T 421 T Sbjct: 1618 T 1618 Score = 31.5 bits (68), Expect = 1.9 Identities = 14/31 (45%), Positives = 16/31 (51%) Frame = +2 Query: 242 CLNNGVCQEALTEHGYVCLCAPGFGGNNCDR 334 CL+ G CQ G CLC PGF G C + Sbjct: 4153 CLHGGTCQ------GTRCLCLPGFSGPRCQQ 4177 >BC109204-1|AAI09205.1| 351|Homo sapiens HSPG2 protein protein. Length = 351 Score = 101 bits (241), Expect = 2e-21 Identities = 59/173 (34%), Positives = 87/173 (50%), Gaps = 6/173 (3%) Frame = +2 Query: 14 PFIAESPDQWTVLELNQPLYIGGVPDFDQLPIDLAG-ASGFVGCISMLILGNEEKNIMAL 190 P S ++ L+LN+ LY+GG PD+ +P AG +SGF+GC+ L + EE L Sbjct: 13 PVNGTSQGKFQGLDLNEELYLGGYPDYGAIP--KAGLSSGFIGCVRELRIQGEEIVFHDL 70 Query: 191 ALEKENVQNCFTCAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRI-GESCRPGLCG 367 L + +C TC C N G C ++ YVC+C GF G+ C+ C P CG Sbjct: 71 NLTAHGISHCPTCRDRPCQNGGQCHDS-ESSSYVCVCPAGFTGSRCEHSQALHCHPEACG 129 Query: 368 P-GKCMNTAD--SYKCACPVTYTGKNCEVKQLIEYPAFTGS-A*LAIKPPTST 514 P C+N D Y C C + +G CE + P+ +G+ + LA+ T+T Sbjct: 130 PDATCVNRPDGRGYTCRCHLGRSGLRCEEGVTVTTPSLSGAGSYLALPALTNT 182 Score = 31.1 bits (67), Expect = 2.6 Identities = 19/78 (24%), Positives = 35/78 (44%), Gaps = 1/78 (1%) Frame = +2 Query: 5 NSG-PFIAESPDQWTVLELNQPLYIGGVPDFDQLPIDLAGASGFVGCISMLILGNEEKNI 181 N G P + SP + L L+ LY+GGV L ++ F GC+ + + + ++ Sbjct: 265 NGGRPVLRSSPGKSQGLNLHTLLYLGGVEPSVPLSPATNMSAHFRGCVGEVSVNGKRLDL 324 Query: 182 MALALEKENVQNCFTCAP 235 L + + C+ +P Sbjct: 325 TYSFLGSQGIGQCYDSSP 342 >AL590556-2|CAH71870.1| 4391|Homo sapiens heparan sulfate proteoglycan 2 protein. Length = 4391 Score = 101 bits (241), Expect = 2e-21 Identities = 59/173 (34%), Positives = 87/173 (50%), Gaps = 6/173 (3%) Frame = +2 Query: 14 PFIAESPDQWTVLELNQPLYIGGVPDFDQLPIDLAG-ASGFVGCISMLILGNEEKNIMAL 190 P S ++ L+LN+ LY+GG PD+ +P AG +SGF+GC+ L + EE L Sbjct: 3778 PVNGTSQGKFQGLDLNEELYLGGYPDYGAIP--KAGLSSGFIGCVRELRIQGEEIVFHDL 3835 Query: 191 ALEKENVQNCFTCAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRI-GESCRPGLCG 367 L + +C TC C N G C ++ YVC+C GF G+ C+ C P CG Sbjct: 3836 NLTAHGISHCPTCRDRPCQNGGQCHDS-ESSSYVCVCPAGFTGSRCEHSQALHCHPEACG 3894 Query: 368 P-GKCMNTAD--SYKCACPVTYTGKNCEVKQLIEYPAFTGS-A*LAIKPPTST 514 P C+N D Y C C + +G CE + P+ +G+ + LA+ T+T Sbjct: 3895 PDATCVNRPDGRGYTCRCHLGRSGLRCEEGVTVTTPSLSGAGSYLALPALTNT 3947 Score = 56.4 bits (130), Expect = 6e-08 Identities = 41/153 (26%), Positives = 67/153 (43%), Gaps = 7/153 (4%) Frame = +2 Query: 5 NSG-PFIAESPDQWTVLELNQPLYIGGVPDFDQLPIDLAGASGFVGCISMLILGNEEKNI 181 N G P + SP + L L+ LY+GGV L ++ F GC+ + + + ++ Sbjct: 4030 NGGRPVLRSSPGKSQGLNLHTLLYLGGVEPSVPLSPATNMSAHFRGCVGEVSVNGKRLDL 4089 Query: 182 MALALEKENVQNCFTCAP---NLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCR 352 L + + C+ +P C + C A E+ + CLC GF G+ C+ C+ Sbjct: 4090 TYSFLGSQGIGQCYDSSPCERQPCQHGATCMPA-GEYEFQCLCRDGFKGDLCEHEENPCQ 4148 Query: 353 ---PGLCGPGKCMNTADSYKCACPVTYTGKNCE 442 P L G G C T +C C ++G C+ Sbjct: 4149 LREPCLHG-GTCQGT----RCLCLPGFSGPRCQ 4176 Score = 31.5 bits (68), Expect = 1.9 Identities = 20/61 (32%), Positives = 21/61 (34%) Frame = +2 Query: 239 LCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLCGPGKCMNTADSYKCACPV 418 LC NG E G C G C E C PG G D CACP+ Sbjct: 1562 LCECNGHSDLCHPETGACSQCQHNAAGEFC----ELCAPGYYGDATAGTPEDCQPCACPL 1617 Query: 419 T 421 T Sbjct: 1618 T 1618 Score = 31.5 bits (68), Expect = 1.9 Identities = 14/31 (45%), Positives = 16/31 (51%) Frame = +2 Query: 242 CLNNGVCQEALTEHGYVCLCAPGFGGNNCDR 334 CL+ G CQ G CLC PGF G C + Sbjct: 4153 CLHGGTCQ------GTRCLCLPGFSGPRCQQ 4177 >AL590103-2|CAI12125.1| 4391|Homo sapiens heparan sulfate proteoglycan 2 protein. Length = 4391 Score = 101 bits (241), Expect = 2e-21 Identities = 59/173 (34%), Positives = 87/173 (50%), Gaps = 6/173 (3%) Frame = +2 Query: 14 PFIAESPDQWTVLELNQPLYIGGVPDFDQLPIDLAG-ASGFVGCISMLILGNEEKNIMAL 190 P S ++ L+LN+ LY+GG PD+ +P AG +SGF+GC+ L + EE L Sbjct: 3778 PVNGTSQGKFQGLDLNEELYLGGYPDYGAIP--KAGLSSGFIGCVRELRIQGEEIVFHDL 3835 Query: 191 ALEKENVQNCFTCAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRI-GESCRPGLCG 367 L + +C TC C N G C ++ YVC+C GF G+ C+ C P CG Sbjct: 3836 NLTAHGISHCPTCRDRPCQNGGQCHDS-ESSSYVCVCPAGFTGSRCEHSQALHCHPEACG 3894 Query: 368 P-GKCMNTAD--SYKCACPVTYTGKNCEVKQLIEYPAFTGS-A*LAIKPPTST 514 P C+N D Y C C + +G CE + P+ +G+ + LA+ T+T Sbjct: 3895 PDATCVNRPDGRGYTCRCHLGRSGLRCEEGVTVTTPSLSGAGSYLALPALTNT 3947 Score = 56.4 bits (130), Expect = 6e-08 Identities = 41/153 (26%), Positives = 67/153 (43%), Gaps = 7/153 (4%) Frame = +2 Query: 5 NSG-PFIAESPDQWTVLELNQPLYIGGVPDFDQLPIDLAGASGFVGCISMLILGNEEKNI 181 N G P + SP + L L+ LY+GGV L ++ F GC+ + + + ++ Sbjct: 4030 NGGRPVLRSSPGKSQGLNLHTLLYLGGVEPSVPLSPATNMSAHFRGCVGEVSVNGKRLDL 4089 Query: 182 MALALEKENVQNCFTCAP---NLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCR 352 L + + C+ +P C + C A E+ + CLC GF G+ C+ C+ Sbjct: 4090 TYSFLGSQGIGQCYDSSPCERQPCQHGATCMPA-GEYEFQCLCRDGFKGDLCEHEENPCQ 4148 Query: 353 ---PGLCGPGKCMNTADSYKCACPVTYTGKNCE 442 P L G G C T +C C ++G C+ Sbjct: 4149 LREPCLHG-GTCQGT----RCLCLPGFSGPRCQ 4176 Score = 31.5 bits (68), Expect = 1.9 Identities = 20/61 (32%), Positives = 21/61 (34%) Frame = +2 Query: 239 LCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLCGPGKCMNTADSYKCACPV 418 LC NG E G C G C E C PG G D CACP+ Sbjct: 1562 LCECNGHSDLCHPETGACSQCQHNAAGEFC----ELCAPGYYGDATAGTPEDCQPCACPL 1617 Query: 419 T 421 T Sbjct: 1618 T 1618 Score = 31.5 bits (68), Expect = 1.9 Identities = 14/31 (45%), Positives = 16/31 (51%) Frame = +2 Query: 242 CLNNGVCQEALTEHGYVCLCAPGFGGNNCDR 334 CL+ G CQ G CLC PGF G C + Sbjct: 4153 CLHGGTCQ------GTRCLCLPGFSGPRCQQ 4177 >AL445795-1|CAC18534.1| 4370|Homo sapiens heparan sulfate proteoglycan perlecan protein. Length = 4370 Score = 101 bits (241), Expect = 2e-21 Identities = 59/173 (34%), Positives = 87/173 (50%), Gaps = 6/173 (3%) Frame = +2 Query: 14 PFIAESPDQWTVLELNQPLYIGGVPDFDQLPIDLAG-ASGFVGCISMLILGNEEKNIMAL 190 P S ++ L+LN+ LY+GG PD+ +P AG +SGF+GC+ L + EE L Sbjct: 3757 PVNGTSQGKFQGLDLNEELYLGGYPDYGAIP--KAGLSSGFIGCVRELRIQGEEIVFHDL 3814 Query: 191 ALEKENVQNCFTCAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRI-GESCRPGLCG 367 L + +C TC C N G C ++ YVC+C GF G+ C+ C P CG Sbjct: 3815 NLTAHGISHCPTCRDRPCQNGGQCHDS-ESSSYVCVCPAGFTGSRCEHSQALHCHPEACG 3873 Query: 368 P-GKCMNTAD--SYKCACPVTYTGKNCEVKQLIEYPAFTGS-A*LAIKPPTST 514 P C+N D Y C C + +G CE + P+ +G+ + LA+ T+T Sbjct: 3874 PDATCVNRPDGRGYTCRCHLGRSGLRCEEGVTVTTPSLSGAGSYLALPALTNT 3926 Score = 56.4 bits (130), Expect = 6e-08 Identities = 41/153 (26%), Positives = 67/153 (43%), Gaps = 7/153 (4%) Frame = +2 Query: 5 NSG-PFIAESPDQWTVLELNQPLYIGGVPDFDQLPIDLAGASGFVGCISMLILGNEEKNI 181 N G P + SP + L L+ LY+GGV L ++ F GC+ + + + ++ Sbjct: 4009 NGGRPVLRSSPGKSQGLNLHTLLYLGGVEPSVPLSPATNMSAHFRGCVGEVSVNGKRLDL 4068 Query: 182 MALALEKENVQNCFTCAP---NLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCR 352 L + + C+ +P C + C A E+ + CLC GF G+ C+ C+ Sbjct: 4069 TYSFLGSQGIGQCYDSSPCERQPCQHGATCMPA-GEYEFQCLCRDGFKGDLCEHEENPCQ 4127 Query: 353 ---PGLCGPGKCMNTADSYKCACPVTYTGKNCE 442 P L G G C T +C C ++G C+ Sbjct: 4128 LREPCLHG-GTCQGT----RCLCLPGFSGPRCQ 4155 Score = 31.5 bits (68), Expect = 1.9 Identities = 20/61 (32%), Positives = 21/61 (34%) Frame = +2 Query: 239 LCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLCGPGKCMNTADSYKCACPV 418 LC NG E G C G C E C PG G D CACP+ Sbjct: 1541 LCECNGHSDLCHPETGACSQCQHNAAGEFC----ELCAPGYYGDATAGTPEDCQPCACPL 1596 Query: 419 T 421 T Sbjct: 1597 T 1597 Score = 31.5 bits (68), Expect = 1.9 Identities = 14/31 (45%), Positives = 16/31 (51%) Frame = +2 Query: 242 CLNNGVCQEALTEHGYVCLCAPGFGGNNCDR 334 CL+ G CQ G CLC PGF G C + Sbjct: 4132 CLHGGTCQ------GTRCLCLPGFSGPRCQQ 4156 >AB209851-1|BAD93088.1| 2331|Homo sapiens Basement membrane-specific heparan sulfate proteoglycan core protein precursor protein. Length = 2331 Score = 101 bits (241), Expect = 2e-21 Identities = 59/173 (34%), Positives = 87/173 (50%), Gaps = 6/173 (3%) Frame = +2 Query: 14 PFIAESPDQWTVLELNQPLYIGGVPDFDQLPIDLAG-ASGFVGCISMLILGNEEKNIMAL 190 P S ++ L+LN+ LY+GG PD+ +P AG +SGF+GC+ L + EE L Sbjct: 1718 PVNGTSQGKFQGLDLNEELYLGGYPDYGAIP--KAGLSSGFIGCVRELRIQGEEIVFHDL 1775 Query: 191 ALEKENVQNCFTCAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRI-GESCRPGLCG 367 L + +C TC C N G C ++ YVC+C GF G+ C+ C P CG Sbjct: 1776 NLTAHGISHCPTCRDRPCQNGGQCHDS-ESSSYVCVCPAGFTGSRCEHSQALHCHPEACG 1834 Query: 368 P-GKCMNTAD--SYKCACPVTYTGKNCEVKQLIEYPAFTGS-A*LAIKPPTST 514 P C+N D Y C C + +G CE + P+ +G+ + LA+ T+T Sbjct: 1835 PDATCVNRPDGRGYTCRCHLGRSGLRCEEGVTVTTPSLSGAGSYLALPALTNT 1887 Score = 56.4 bits (130), Expect = 6e-08 Identities = 41/153 (26%), Positives = 67/153 (43%), Gaps = 7/153 (4%) Frame = +2 Query: 5 NSG-PFIAESPDQWTVLELNQPLYIGGVPDFDQLPIDLAGASGFVGCISMLILGNEEKNI 181 N G P + SP + L L+ LY+GGV L ++ F GC+ + + + ++ Sbjct: 1970 NGGRPVLRSSPGKSQGLNLHTLLYLGGVEPSVPLSPATNMSAHFRGCVGEVSVNGKRLDL 2029 Query: 182 MALALEKENVQNCFTCAP---NLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCR 352 L + + C+ +P C + C A E+ + CLC GF G+ C+ C+ Sbjct: 2030 TYSFLGSQGIGQCYDSSPCERQPCQHGATCMPA-GEYEFQCLCRDGFKGDLCEHEENPCQ 2088 Query: 353 ---PGLCGPGKCMNTADSYKCACPVTYTGKNCE 442 P L G G C T +C C ++G C+ Sbjct: 2089 LREPCLHG-GTCQGT----RCLCLPGFSGPRCQ 2116 Score = 31.5 bits (68), Expect = 1.9 Identities = 14/31 (45%), Positives = 16/31 (51%) Frame = +2 Query: 242 CLNNGVCQEALTEHGYVCLCAPGFGGNNCDR 334 CL+ G CQ G CLC PGF G C + Sbjct: 2093 CLHGGTCQ------GTRCLCLPGFSGPRCQQ 2117 >U97669-1|AAB91371.1| 2321|Homo sapiens Notch3 protein. Length = 2321 Score = 74.5 bits (175), Expect = 2e-13 Identities = 32/77 (41%), Positives = 40/77 (51%) Frame = +2 Query: 212 QNCFTCAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLCGPGKCMNTA 391 Q+ C PN CLN G CQ+ + + C C PGF G C R + C CGPG C + Sbjct: 848 QDINDCDPNPCLNGGSCQDGVGS--FSCSCLPGFAGPRCARDVDECLSNPCGPGTCTDHV 905 Query: 392 DSYKCACPVTYTGKNCE 442 S+ C CP Y G +CE Sbjct: 906 ASFTCTCPPGYGGFHCE 922 Score = 67.3 bits (157), Expect = 3e-11 Identities = 30/72 (41%), Positives = 36/72 (50%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLCGPGKCMNTADSYKC 406 CA C N C + GY C CA GF G CDR + C P C G+C++ S+ C Sbjct: 511 CASTPCRNGAKCVDQ--PDGYECRCAEGFEGTLCDRNVDDCSPDPCHHGRCVDGIASFSC 568 Query: 407 ACPVTYTGKNCE 442 AC YTG CE Sbjct: 569 ACAPGYTGTRCE 580 Score = 65.3 bits (152), Expect = 1e-10 Identities = 30/79 (37%), Positives = 43/79 (54%), Gaps = 1/79 (1%) Frame = +2 Query: 212 QNCFTCAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLC-GPGKCMNT 388 +N C+P+ C ++G C + + + C CAPG+ G C+ + CR C GKC++ Sbjct: 544 RNVDDCSPDPC-HHGRCVDGIAS--FSCACAPGYTGTRCESQVDECRSQPCRHGGKCLDL 600 Query: 389 ADSYKCACPVTYTGKNCEV 445 D Y C CP TG NCEV Sbjct: 601 VDKYLCRCPSGTTGVNCEV 619 Score = 63.7 bits (148), Expect = 4e-10 Identities = 27/72 (37%), Positives = 40/72 (55%), Gaps = 1/72 (1%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLC-GPGKCMNTADSYK 403 CAP+ C N G C+++ + Y C C PGF G NC+ + C C G C++ ++Y Sbjct: 201 CAPSPCRNGGTCRQS-GDLTYDCACLPGFEGQNCEVNVDDCPGHRCLNGGTCVDGVNTYN 259 Query: 404 CACPVTYTGKNC 439 C CP +TG+ C Sbjct: 260 CQCPPEWTGQFC 271 Score = 58.8 bits (136), Expect = 1e-08 Identities = 29/74 (39%), Positives = 38/74 (51%), Gaps = 2/74 (2%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCR-PGLCGP-GKCMNTADSY 400 C PN C + G C+ A + VC C G+ G C + + C P CGP G C N A S+ Sbjct: 775 CTPNPCEHGGRCESAPGQLP-VCSCPQGWQGPRCQQDVDECAGPAPCGPHGICTNLAGSF 833 Query: 401 KCACPVTYTGKNCE 442 C C YTG +C+ Sbjct: 834 SCTCHGGYTGPSCD 847 Score = 58.0 bits (134), Expect = 2e-08 Identities = 27/75 (36%), Positives = 35/75 (46%), Gaps = 3/75 (4%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGL--CGP-GKCMNTADS 397 C N C + +C +C C PGF G CD+ + C G C G+C+NT S Sbjct: 355 CVSNPCHEDAICDTNPVNGRAICTCPPGFTGGACDQDVDECSIGANPCEHLGRCVNTQGS 414 Query: 398 YKCACPVTYTGKNCE 442 + C C YTG CE Sbjct: 415 FLCQCGRGYTGPRCE 429 Score = 58.0 bits (134), Expect = 2e-08 Identities = 25/74 (33%), Positives = 39/74 (52%), Gaps = 2/74 (2%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESC--RPGLCGPGKCMNTADSY 400 C+P+ C N G C + + + + CLC PG+ G +C + C RP L G G C + Sbjct: 928 CSPSSCFNGGTCVDGV--NSFSCLCRPGYTGAHCQHEADPCLSRPCLHG-GVCSAAHPGF 984 Query: 401 KCACPVTYTGKNCE 442 +C C ++TG C+ Sbjct: 985 RCTCLESFTGPQCQ 998 Score = 57.6 bits (133), Expect = 3e-08 Identities = 28/78 (35%), Positives = 39/78 (50%), Gaps = 6/78 (7%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCD------RIGESCRPGLCGPGKCMNT 388 C + C + C + ++C C PG+ G +C R+GE CR G G C+NT Sbjct: 123 CLSSPCAHGARCSVG-PDGRFLCSCPPGYQGRSCRSDVDECRVGEPCRHG----GTCLNT 177 Query: 389 ADSYKCACPVTYTGKNCE 442 S++C CP YTG CE Sbjct: 178 PGSFRCQCPAGYTGPLCE 195 Score = 57.6 bits (133), Expect = 3e-08 Identities = 29/92 (31%), Positives = 42/92 (45%), Gaps = 5/92 (5%) Frame = +2 Query: 242 CLNNGVCQEALTEH--GYVCLCAPGFGGNNCDRIGESCRPGLC-GPGKCMNTADSYKCAC 412 CL+N T+H + C C PG+GG +C++ C P C G C++ +S+ C C Sbjct: 891 CLSNPCGPGTCTDHVASFTCTCPPGYGGFHCEQDLPDCSPSSCFNGGTCVDGVNSFSCLC 950 Query: 413 PVTYTGKNC--EVKQLIEYPAFTGSA*LAIKP 502 YTG +C E + P G A P Sbjct: 951 RPGYTGAHCQHEADPCLSRPCLHGGVCSAAHP 982 Score = 57.2 bits (132), Expect = 3e-08 Identities = 24/73 (32%), Positives = 38/73 (52%), Gaps = 1/73 (1%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLCGPG-KCMNTADSYK 403 C + C+N GVC++ + +G+ C C GF G+ C + C C G KC++ D Y+ Sbjct: 473 CQSSPCVNGGVCKDRV--NGFSCTCPSGFSGSTCQLDVDECASTPCRNGAKCVDQPDGYE 530 Query: 404 CACPVTYTGKNCE 442 C C + G C+ Sbjct: 531 CRCAEGFEGTLCD 543 Score = 54.8 bits (126), Expect = 2e-07 Identities = 24/76 (31%), Positives = 37/76 (48%), Gaps = 1/76 (1%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLC-GPGKCMNTADSYK 403 C C + G C+ + GY+C C PG+ G+NC+ + C C G C++ Y Sbjct: 1088 CLAQPCQHGGTCRGYMG--GYMCECLPGYNGDNCEDDVDECASQPCQHGGSCIDLVARYL 1145 Query: 404 CACPVTYTGKNCEVKQ 451 C+CP G CE+ + Sbjct: 1146 CSCPPGTLGVLCEINE 1161 Score = 51.2 bits (117), Expect = 2e-06 Identities = 27/85 (31%), Positives = 39/85 (45%), Gaps = 4/85 (4%) Frame = +2 Query: 197 EKENVQ-NCFTCAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCR--PGLC- 364 E +N + N C + CLN G C + + Y C C P + G C + C+ P C Sbjct: 229 EGQNCEVNVDDCPGHRCLNGGTCVDGVNT--YNCQCPPEWTGQFCTEDVDECQLQPNACH 286 Query: 365 GPGKCMNTADSYKCACPVTYTGKNC 439 G C NT + C C +TG++C Sbjct: 287 NGGTCFNTLGGHSCVCVNGWTGESC 311 Score = 50.8 bits (116), Expect = 3e-06 Identities = 27/80 (33%), Positives = 37/80 (46%), Gaps = 8/80 (10%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGL---CGP-----GKCM 382 CA C + G C + + Y+C C PG G C+ + C PG GP G C+ Sbjct: 1126 CASQPCQHGGSCIDLVAR--YLCSCPPGTLGVLCEINEDDCGPGPPLDSGPRCLHNGTCV 1183 Query: 383 NTADSYKCACPVTYTGKNCE 442 + ++C CP YTG CE Sbjct: 1184 DLVGGFRCTCPPGYTGLRCE 1203 Score = 50.4 bits (115), Expect = 4e-06 Identities = 25/75 (33%), Positives = 34/75 (45%), Gaps = 4/75 (5%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHG---YVCLCAPGFGGNNCDRIGESCRPGLCGPG-KCMNTAD 394 C C + G C+ + G + C CA F G C+R+ SCR C G C T Sbjct: 1250 CESQPCQHGGQCRPSPGPGGGLTFTCHCAQPFWGPRCERVARSCRELQCPVGVPCQQTPR 1309 Query: 395 SYKCACPVTYTGKNC 439 +CACP +G +C Sbjct: 1310 GPRCACPPGLSGPSC 1324 Score = 50.0 bits (114), Expect = 5e-06 Identities = 25/77 (32%), Positives = 38/77 (49%), Gaps = 1/77 (1%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLC-GPGKCMNTADSYK 403 C CL+ GVC A G+ C C F G C + + C C G+C+ T +Y Sbjct: 966 CLSRPCLHGGVCSAA--HPGFRCTCLESFTGPQCQTLVDWCSRQPCQNGGRCVQTG-AY- 1021 Query: 404 CACPVTYTGKNCEVKQL 454 C CP ++G+ C+++ L Sbjct: 1022 CLCPPGWSGRLCDIRSL 1038 Score = 49.6 bits (113), Expect = 7e-06 Identities = 19/74 (25%), Positives = 34/74 (45%), Gaps = 1/74 (1%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLC-GPGKCMNTADSYK 403 C C N C + + + + C+C GF G C+ + C+ C G C + + + Sbjct: 435 CLSGPCRNQATCLDRIGQ--FTCICMAGFTGTYCEVDIDECQSSPCVNGGVCKDRVNGFS 492 Query: 404 CACPVTYTGKNCEV 445 C CP ++G C++ Sbjct: 493 CTCPSGFSGSTCQL 506 Score = 49.6 bits (113), Expect = 7e-06 Identities = 24/68 (35%), Positives = 34/68 (50%), Gaps = 1/68 (1%) Frame = +2 Query: 215 NCFTCAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLCGP-GKCMNTA 391 N CA N C GVC++ + Y C+C PGF G C+ C CG G C++ Sbjct: 620 NIDDCASNPC-TFGVCRDGINR--YDCVCQPGFTGPLCNVEINECASSPCGEGGSCVDGE 676 Query: 392 DSYKCACP 415 + ++C CP Sbjct: 677 NGFRCLCP 684 Score = 49.2 bits (112), Expect = 9e-06 Identities = 27/84 (32%), Positives = 37/84 (44%), Gaps = 2/84 (2%) Frame = +2 Query: 200 KENVQNCFTCAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLC-GPGK 376 + +V C P C + G C T + C C G+ G C+ C P C G Sbjct: 156 RSDVDECRVGEP--CRHGGTCLN--TPGSFRCQCPAGYTGPLCENPAVPCAPSPCRNGGT 211 Query: 377 CMNTAD-SYKCACPVTYTGKNCEV 445 C + D +Y CAC + G+NCEV Sbjct: 212 CRQSGDLTYDCACLPGFEGQNCEV 235 Score = 47.6 bits (108), Expect = 3e-05 Identities = 22/74 (29%), Positives = 33/74 (44%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLCGPGKCMNTADSYKC 406 C C + G C + + + Y+C C G G NC+ + C C G C + + Y C Sbjct: 586 CRSQPCRHGGKCLDLVDK--YLCRCPSGTTGVNCEVNIDDCASNPCTFGVCRDGINRYDC 643 Query: 407 ACPVTYTGKNCEVK 448 C +TG C V+ Sbjct: 644 VCQPGFTGPLCNVE 657 Score = 47.2 bits (107), Expect = 4e-05 Identities = 23/76 (30%), Positives = 37/76 (48%), Gaps = 3/76 (3%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDR--IGESCRPGLC-GPGKCMNTADS 397 CA C ++G+C +A G+ C+C PG+ G C + ++C C G C + Sbjct: 699 CAHEPC-SHGICYDA--PGGFRCVCEPGWSGPRCSQSLARDACESQPCRAGGTCSSDGMG 755 Query: 398 YKCACPVTYTGKNCEV 445 + C CP G+ CE+ Sbjct: 756 FHCTCPPGVQGRQCEL 771 Score = 47.2 bits (107), Expect = 4e-05 Identities = 28/83 (33%), Positives = 36/83 (43%), Gaps = 11/83 (13%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPG----------LC-GPG 373 C+ C N G C + G CLC PG+ G CD CR LC G Sbjct: 1004 CSRQPCQNGGRCVQT----GAYCLCPPGWSGRLCDIRSLPCREAAAQIGVRLEQLCQAGG 1059 Query: 374 KCMNTADSYKCACPVTYTGKNCE 442 +C++ S+ C CP TG +CE Sbjct: 1060 QCVDEDSSHYCVCPEGRTGSHCE 1082 Score = 47.2 bits (107), Expect = 4e-05 Identities = 21/71 (29%), Positives = 34/71 (47%), Gaps = 4/71 (5%) Frame = +2 Query: 242 CLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLCGPG---KCM-NTADSYKCA 409 CL+NG C + + G+ C C PG+ G C+ CR G C C+ + ++C Sbjct: 1176 CLHNGTCVDLVG--GFRCTCPPGYTGLRCEADINECRSGACHAAHTRDCLQDPGGGFRCL 1233 Query: 410 CPVTYTGKNCE 442 C ++G C+ Sbjct: 1234 CHAGFSGPRCQ 1244 Score = 46.8 bits (106), Expect = 5e-05 Identities = 26/97 (26%), Positives = 43/97 (44%), Gaps = 3/97 (3%) Frame = +2 Query: 200 KENVQNCFTCAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLC-GPGK 376 +++V C AP C +G+C + C C G+ G +CD+ C P C G Sbjct: 808 QQDVDECAGPAP--CGPHGICTNLAGS--FSCTCHGGYTGPSCDQDINDCDPNPCLNGGS 863 Query: 377 CMNTADSYKCACPVTYTGKNC--EVKQLIEYPAFTGS 481 C + S+ C+C + G C +V + + P G+ Sbjct: 864 CQDGVGSFSCSCLPGFAGPRCARDVDECLSNPCGPGT 900 Score = 46.0 bits (104), Expect = 8e-05 Identities = 23/82 (28%), Positives = 36/82 (43%), Gaps = 1/82 (1%) Frame = +2 Query: 203 ENVQNCFTCAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLC-GPGKC 379 ++V C + N C + G C T+ ++C C G+ G C+ C G C C Sbjct: 390 QDVDEC-SIGANPCEHLGRCVN--TQGSFLCQCGRGYTGPRCETDVNECLSGPCRNQATC 446 Query: 380 MNTADSYKCACPVTYTGKNCEV 445 ++ + C C +TG CEV Sbjct: 447 LDRIGQFTCICMAGFTGTYCEV 468 Score = 45.2 bits (102), Expect = 1e-04 Identities = 23/73 (31%), Positives = 35/73 (47%), Gaps = 5/73 (6%) Frame = +2 Query: 242 CLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLC-GPGKCMNTADS----YKC 406 C N G C + L CLC PG+ G C ++ + C G C G G C ++ + + C Sbjct: 49 CANGGRCTQ-LPSREAACLCPPGWVGERC-QLEDPCHSGPCAGRGVCQSSVVAGTARFSC 106 Query: 407 ACPVTYTGKNCEV 445 CP + G +C + Sbjct: 107 RCPRGFRGPDCSL 119 Score = 44.4 bits (100), Expect = 3e-04 Identities = 21/71 (29%), Positives = 30/71 (42%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLCGPGKCMNTADSYKC 406 CA + C G C + E+G+ CLC PG C C C G C + ++C Sbjct: 661 CASSPCGEGGSCVDG--ENGFRCLCPPGSLPPLCLPPSHPCAHEPCSHGICYDAPGGFRC 718 Query: 407 ACPVTYTGKNC 439 C ++G C Sbjct: 719 VCEPGWSGPRC 729 Score = 43.2 bits (97), Expect = 6e-04 Identities = 22/69 (31%), Positives = 30/69 (43%), Gaps = 1/69 (1%) Frame = +2 Query: 239 LCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLC-GPGKCMNTADSYKCACP 415 LC G C + + H C+C G G++C++ + C C G C Y C C Sbjct: 1054 LCQAGGQCVDEDSSH--YCVCPEGRTGSHCEQEVDPCLAQPCQHGGTCRGYMGGYMCECL 1111 Query: 416 VTYTGKNCE 442 Y G NCE Sbjct: 1112 PGYNGDNCE 1120 Score = 34.3 bits (75), Expect = 0.27 Identities = 17/59 (28%), Positives = 22/59 (37%), Gaps = 6/59 (10%) Frame = +2 Query: 284 GYVCLCAPGFGGNNCDRIGESCRP------GLCGPGKCMNTADSYKCACPVTYTGKNCE 442 G+ CLC GF G C + C G C P ++ C C + G CE Sbjct: 1229 GFRCLCHAGFSGPRCQTVLSPCESQPCQHGGQCRPSPGPGGGLTFTCHCAQPFWGPRCE 1287 Score = 33.5 bits (73), Expect = 0.48 Identities = 25/85 (29%), Positives = 33/85 (38%), Gaps = 12/85 (14%) Frame = +2 Query: 224 TCAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGL----CGPGKCMN-- 385 +C C CQ+ T G C C PG G +C R PG C C++ Sbjct: 1292 SCRELQCPVGVPCQQ--TPRGPRCACPPGLSGPSC-RSFPGSPPGASNASCAAAPCLHGG 1348 Query: 386 ------TADSYKCACPVTYTGKNCE 442 A ++CAC +TG CE Sbjct: 1349 SCRPAPLAPFFRCACAQGWTGPRCE 1373 >AF058900-1|AAC14346.1| 2321|Homo sapiens Notch3 protein. Length = 2321 Score = 74.5 bits (175), Expect = 2e-13 Identities = 32/77 (41%), Positives = 40/77 (51%) Frame = +2 Query: 212 QNCFTCAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLCGPGKCMNTA 391 Q+ C PN CLN G CQ+ + + C C PGF G C R + C CGPG C + Sbjct: 848 QDINDCDPNPCLNGGSCQDGVGS--FSCSCLPGFAGPRCARDVDECLSNPCGPGTCTDHV 905 Query: 392 DSYKCACPVTYTGKNCE 442 S+ C CP Y G +CE Sbjct: 906 ASFTCTCPPGYGGFHCE 922 Score = 67.3 bits (157), Expect = 3e-11 Identities = 30/72 (41%), Positives = 36/72 (50%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLCGPGKCMNTADSYKC 406 CA C N C + GY C CA GF G CDR + C P C G+C++ S+ C Sbjct: 511 CASTPCRNGAKCVDQ--PDGYECRCAEGFEGTLCDRNVDDCSPDPCHHGRCVDGIASFSC 568 Query: 407 ACPVTYTGKNCE 442 AC YTG CE Sbjct: 569 ACAPGYTGTRCE 580 Score = 65.3 bits (152), Expect = 1e-10 Identities = 30/79 (37%), Positives = 43/79 (54%), Gaps = 1/79 (1%) Frame = +2 Query: 212 QNCFTCAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLC-GPGKCMNT 388 +N C+P+ C ++G C + + + C CAPG+ G C+ + CR C GKC++ Sbjct: 544 RNVDDCSPDPC-HHGRCVDGIAS--FSCACAPGYTGTRCESQVDECRSQPCRHGGKCLDL 600 Query: 389 ADSYKCACPVTYTGKNCEV 445 D Y C CP TG NCEV Sbjct: 601 VDKYLCRCPSGTTGVNCEV 619 Score = 63.7 bits (148), Expect = 4e-10 Identities = 27/72 (37%), Positives = 40/72 (55%), Gaps = 1/72 (1%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLC-GPGKCMNTADSYK 403 CAP+ C N G C+++ + Y C C PGF G NC+ + C C G C++ ++Y Sbjct: 201 CAPSPCRNGGTCRQS-GDLTYDCACLPGFEGQNCEVNVDDCPGHRCLNGGTCVDGVNTYN 259 Query: 404 CACPVTYTGKNC 439 C CP +TG+ C Sbjct: 260 CQCPPEWTGQFC 271 Score = 58.8 bits (136), Expect = 1e-08 Identities = 29/74 (39%), Positives = 38/74 (51%), Gaps = 2/74 (2%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCR-PGLCGP-GKCMNTADSY 400 C PN C + G C+ A + VC C G+ G C + + C P CGP G C N A S+ Sbjct: 775 CTPNPCEHGGRCESAPGQLP-VCSCPQGWQGPRCQQDVDECAGPAPCGPHGICTNLAGSF 833 Query: 401 KCACPVTYTGKNCE 442 C C YTG +C+ Sbjct: 834 SCTCHGGYTGPSCD 847 Score = 58.0 bits (134), Expect = 2e-08 Identities = 27/75 (36%), Positives = 35/75 (46%), Gaps = 3/75 (4%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGL--CGP-GKCMNTADS 397 C N C + +C +C C PGF G CD+ + C G C G+C+NT S Sbjct: 355 CVSNPCHEDAICDTNPVNGRAICTCPPGFTGGACDQDVDECSIGANPCEHLGRCVNTQGS 414 Query: 398 YKCACPVTYTGKNCE 442 + C C YTG CE Sbjct: 415 FLCQCGRGYTGPRCE 429 Score = 58.0 bits (134), Expect = 2e-08 Identities = 25/74 (33%), Positives = 39/74 (52%), Gaps = 2/74 (2%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESC--RPGLCGPGKCMNTADSY 400 C+P+ C N G C + + + + CLC PG+ G +C + C RP L G G C + Sbjct: 928 CSPSSCFNGGTCVDGV--NSFSCLCRPGYTGAHCQHEADPCLSRPCLHG-GVCSAAHPGF 984 Query: 401 KCACPVTYTGKNCE 442 +C C ++TG C+ Sbjct: 985 RCTCLESFTGPQCQ 998 Score = 57.6 bits (133), Expect = 3e-08 Identities = 28/78 (35%), Positives = 39/78 (50%), Gaps = 6/78 (7%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCD------RIGESCRPGLCGPGKCMNT 388 C + C + C + ++C C PG+ G +C R+GE CR G G C+NT Sbjct: 123 CLSSPCAHGARCSVG-PDGRFLCSCPPGYQGRSCRSDVDECRVGEPCRHG----GTCLNT 177 Query: 389 ADSYKCACPVTYTGKNCE 442 S++C CP YTG CE Sbjct: 178 PGSFRCQCPAGYTGPLCE 195 Score = 57.6 bits (133), Expect = 3e-08 Identities = 29/92 (31%), Positives = 42/92 (45%), Gaps = 5/92 (5%) Frame = +2 Query: 242 CLNNGVCQEALTEH--GYVCLCAPGFGGNNCDRIGESCRPGLC-GPGKCMNTADSYKCAC 412 CL+N T+H + C C PG+GG +C++ C P C G C++ +S+ C C Sbjct: 891 CLSNPCGPGTCTDHVASFTCTCPPGYGGFHCEQDLPDCSPSSCFNGGTCVDGVNSFSCLC 950 Query: 413 PVTYTGKNC--EVKQLIEYPAFTGSA*LAIKP 502 YTG +C E + P G A P Sbjct: 951 RPGYTGAHCQHEADPCLSRPCLHGGVCSAAHP 982 Score = 57.2 bits (132), Expect = 3e-08 Identities = 24/73 (32%), Positives = 38/73 (52%), Gaps = 1/73 (1%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLCGPG-KCMNTADSYK 403 C + C+N GVC++ + +G+ C C GF G+ C + C C G KC++ D Y+ Sbjct: 473 CQSSPCVNGGVCKDRV--NGFSCTCPSGFSGSTCQLDVDECASTPCRNGAKCVDQPDGYE 530 Query: 404 CACPVTYTGKNCE 442 C C + G C+ Sbjct: 531 CRCAEGFEGTLCD 543 Score = 54.8 bits (126), Expect = 2e-07 Identities = 24/76 (31%), Positives = 37/76 (48%), Gaps = 1/76 (1%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLC-GPGKCMNTADSYK 403 C C + G C+ + GY+C C PG+ G+NC+ + C C G C++ Y Sbjct: 1088 CLAQPCQHGGTCRGYMG--GYMCECLPGYNGDNCEDDVDECASQPCQHGGSCIDLVARYL 1145 Query: 404 CACPVTYTGKNCEVKQ 451 C+CP G CE+ + Sbjct: 1146 CSCPPGTLGVLCEINE 1161 Score = 51.2 bits (117), Expect = 2e-06 Identities = 27/85 (31%), Positives = 39/85 (45%), Gaps = 4/85 (4%) Frame = +2 Query: 197 EKENVQ-NCFTCAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCR--PGLC- 364 E +N + N C + CLN G C + + Y C C P + G C + C+ P C Sbjct: 229 EGQNCEVNVDDCPGHRCLNGGTCVDGVNT--YNCQCPPEWTGQFCTEDVDECQLQPNACH 286 Query: 365 GPGKCMNTADSYKCACPVTYTGKNC 439 G C NT + C C +TG++C Sbjct: 287 NGGTCFNTLGGHSCVCVNGWTGESC 311 Score = 50.8 bits (116), Expect = 3e-06 Identities = 27/80 (33%), Positives = 37/80 (46%), Gaps = 8/80 (10%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGL---CGP-----GKCM 382 CA C + G C + + Y+C C PG G C+ + C PG GP G C+ Sbjct: 1126 CASQPCQHGGSCIDLVAR--YLCSCPPGTLGVLCEINEDDCGPGPPLDSGPRCLHNGTCV 1183 Query: 383 NTADSYKCACPVTYTGKNCE 442 + ++C CP YTG CE Sbjct: 1184 DLVGGFRCTCPPGYTGLRCE 1203 Score = 50.4 bits (115), Expect = 4e-06 Identities = 25/75 (33%), Positives = 34/75 (45%), Gaps = 4/75 (5%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHG---YVCLCAPGFGGNNCDRIGESCRPGLCGPG-KCMNTAD 394 C C + G C+ + G + C CA F G C+R+ SCR C G C T Sbjct: 1250 CESQPCQHGGQCRPSPGPGGGLTFTCHCAQPFWGPRCERVARSCRELQCPVGVPCQQTPR 1309 Query: 395 SYKCACPVTYTGKNC 439 +CACP +G +C Sbjct: 1310 GPRCACPPGLSGPSC 1324 Score = 50.0 bits (114), Expect = 5e-06 Identities = 25/77 (32%), Positives = 38/77 (49%), Gaps = 1/77 (1%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLC-GPGKCMNTADSYK 403 C CL+ GVC A G+ C C F G C + + C C G+C+ T +Y Sbjct: 966 CLSRPCLHGGVCSAA--HPGFRCTCLESFTGPQCQTLVDWCSRQPCQNGGRCVQTG-AY- 1021 Query: 404 CACPVTYTGKNCEVKQL 454 C CP ++G+ C+++ L Sbjct: 1022 CLCPPGWSGRLCDIRSL 1038 Score = 49.6 bits (113), Expect = 7e-06 Identities = 19/74 (25%), Positives = 34/74 (45%), Gaps = 1/74 (1%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLC-GPGKCMNTADSYK 403 C C N C + + + + C+C GF G C+ + C+ C G C + + + Sbjct: 435 CLSGPCRNQATCLDRIGQ--FTCICMAGFTGTYCEVDIDECQSSPCVNGGVCKDRVNGFS 492 Query: 404 CACPVTYTGKNCEV 445 C CP ++G C++ Sbjct: 493 CTCPSGFSGSTCQL 506 Score = 49.6 bits (113), Expect = 7e-06 Identities = 24/68 (35%), Positives = 34/68 (50%), Gaps = 1/68 (1%) Frame = +2 Query: 215 NCFTCAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLCGP-GKCMNTA 391 N CA N C GVC++ + Y C+C PGF G C+ C CG G C++ Sbjct: 620 NIDDCASNPC-TFGVCRDGINR--YDCVCQPGFTGPLCNVEINECASSPCGEGGSCVDGE 676 Query: 392 DSYKCACP 415 + ++C CP Sbjct: 677 NGFRCLCP 684 Score = 49.2 bits (112), Expect = 9e-06 Identities = 27/84 (32%), Positives = 37/84 (44%), Gaps = 2/84 (2%) Frame = +2 Query: 200 KENVQNCFTCAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLC-GPGK 376 + +V C P C + G C T + C C G+ G C+ C P C G Sbjct: 156 RSDVDECRVGEP--CRHGGTCLN--TPGSFRCQCPAGYTGPLCENPAVPCAPSPCRNGGT 211 Query: 377 CMNTAD-SYKCACPVTYTGKNCEV 445 C + D +Y CAC + G+NCEV Sbjct: 212 CRQSGDLTYDCACLPGFEGQNCEV 235 Score = 47.6 bits (108), Expect = 3e-05 Identities = 22/74 (29%), Positives = 33/74 (44%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLCGPGKCMNTADSYKC 406 C C + G C + + + Y+C C G G NC+ + C C G C + + Y C Sbjct: 586 CRSQPCRHGGKCLDLVDK--YLCRCPSGTTGVNCEVNIDDCASNPCTFGVCRDGINRYDC 643 Query: 407 ACPVTYTGKNCEVK 448 C +TG C V+ Sbjct: 644 VCQPGFTGPLCNVE 657 Score = 47.2 bits (107), Expect = 4e-05 Identities = 23/76 (30%), Positives = 37/76 (48%), Gaps = 3/76 (3%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDR--IGESCRPGLC-GPGKCMNTADS 397 CA C ++G+C +A G+ C+C PG+ G C + ++C C G C + Sbjct: 699 CAHEPC-SHGICYDA--PGGFRCVCEPGWSGPRCSQSLARDACESQPCRAGGTCSSDGMG 755 Query: 398 YKCACPVTYTGKNCEV 445 + C CP G+ CE+ Sbjct: 756 FHCTCPPGVQGRQCEL 771 Score = 47.2 bits (107), Expect = 4e-05 Identities = 28/83 (33%), Positives = 36/83 (43%), Gaps = 11/83 (13%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPG----------LC-GPG 373 C+ C N G C + G CLC PG+ G CD CR LC G Sbjct: 1004 CSRQPCQNGGRCVQT----GAYCLCPPGWSGRLCDIRSLPCREAAAQIGVRLEQLCQAGG 1059 Query: 374 KCMNTADSYKCACPVTYTGKNCE 442 +C++ S+ C CP TG +CE Sbjct: 1060 QCVDEDSSHYCVCPEGRTGSHCE 1082 Score = 47.2 bits (107), Expect = 4e-05 Identities = 21/71 (29%), Positives = 34/71 (47%), Gaps = 4/71 (5%) Frame = +2 Query: 242 CLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLCGPG---KCM-NTADSYKCA 409 CL+NG C + + G+ C C PG+ G C+ CR G C C+ + ++C Sbjct: 1176 CLHNGTCVDLVG--GFRCTCPPGYTGLRCEADINECRSGACHAAHTRDCLQDPGGGFRCL 1233 Query: 410 CPVTYTGKNCE 442 C ++G C+ Sbjct: 1234 CHAGFSGPRCQ 1244 Score = 46.8 bits (106), Expect = 5e-05 Identities = 26/97 (26%), Positives = 43/97 (44%), Gaps = 3/97 (3%) Frame = +2 Query: 200 KENVQNCFTCAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLC-GPGK 376 +++V C AP C +G+C + C C G+ G +CD+ C P C G Sbjct: 808 QQDVDECAGPAP--CGPHGICTNLAGS--FSCTCHGGYTGPSCDQDINDCDPNPCLNGGS 863 Query: 377 CMNTADSYKCACPVTYTGKNC--EVKQLIEYPAFTGS 481 C + S+ C+C + G C +V + + P G+ Sbjct: 864 CQDGVGSFSCSCLPGFAGPRCARDVDECLSNPCGPGT 900 Score = 46.0 bits (104), Expect = 8e-05 Identities = 23/82 (28%), Positives = 36/82 (43%), Gaps = 1/82 (1%) Frame = +2 Query: 203 ENVQNCFTCAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLC-GPGKC 379 ++V C + N C + G C T+ ++C C G+ G C+ C G C C Sbjct: 390 QDVDEC-SIGANPCEHLGRCVN--TQGSFLCQCGRGYTGPRCETDVNECLSGPCRNQATC 446 Query: 380 MNTADSYKCACPVTYTGKNCEV 445 ++ + C C +TG CEV Sbjct: 447 LDRIGQFTCICMAGFTGTYCEV 468 Score = 45.2 bits (102), Expect = 1e-04 Identities = 23/73 (31%), Positives = 35/73 (47%), Gaps = 5/73 (6%) Frame = +2 Query: 242 CLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLC-GPGKCMNTADS----YKC 406 C N G C + L CLC PG+ G C ++ + C G C G G C ++ + + C Sbjct: 49 CANGGRCTQ-LPSREAACLCPPGWVGERC-QLEDPCHSGPCAGRGVCQSSVVAGTARFSC 106 Query: 407 ACPVTYTGKNCEV 445 CP + G +C + Sbjct: 107 RCPRGFRGPDCSL 119 Score = 44.4 bits (100), Expect = 3e-04 Identities = 21/71 (29%), Positives = 30/71 (42%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLCGPGKCMNTADSYKC 406 CA + C G C + E+G+ CLC PG C C C G C + ++C Sbjct: 661 CASSPCGEGGSCVDG--ENGFRCLCPPGSLPPLCLPPSHPCAHEPCSHGICYDAPGGFRC 718 Query: 407 ACPVTYTGKNC 439 C ++G C Sbjct: 719 VCEPGWSGPRC 729 Score = 43.2 bits (97), Expect = 6e-04 Identities = 22/69 (31%), Positives = 30/69 (43%), Gaps = 1/69 (1%) Frame = +2 Query: 239 LCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLC-GPGKCMNTADSYKCACP 415 LC G C + + H C+C G G++C++ + C C G C Y C C Sbjct: 1054 LCQAGGQCVDEDSSH--YCVCPEGRTGSHCEQEVDPCLAQPCQHGGTCRGYMGGYMCECL 1111 Query: 416 VTYTGKNCE 442 Y G NCE Sbjct: 1112 PGYNGDNCE 1120 Score = 34.3 bits (75), Expect = 0.27 Identities = 17/59 (28%), Positives = 22/59 (37%), Gaps = 6/59 (10%) Frame = +2 Query: 284 GYVCLCAPGFGGNNCDRIGESCRP------GLCGPGKCMNTADSYKCACPVTYTGKNCE 442 G+ CLC GF G C + C G C P ++ C C + G CE Sbjct: 1229 GFRCLCHAGFSGPRCQTVLSPCESQPCQHGGQCRPSPGPGGGLTFTCHCAQPFWGPRCE 1287 Score = 33.5 bits (73), Expect = 0.48 Identities = 25/85 (29%), Positives = 33/85 (38%), Gaps = 12/85 (14%) Frame = +2 Query: 224 TCAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGL----CGPGKCMN-- 385 +C C CQ+ T G C C PG G +C R PG C C++ Sbjct: 1292 SCRELQCPVGVPCQQ--TPRGPRCACPPGLSGPSC-RSFPGSPPGASNASCAAAPCLHGG 1348 Query: 386 ------TADSYKCACPVTYTGKNCE 442 A ++CAC +TG CE Sbjct: 1349 SCRPAPLAPFFRCACAQGWTGPRCE 1373 >AC004663-1|AAC15789.1| 2281|Homo sapiens Notch 3 protein. Length = 2281 Score = 74.5 bits (175), Expect = 2e-13 Identities = 32/77 (41%), Positives = 40/77 (51%) Frame = +2 Query: 212 QNCFTCAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLCGPGKCMNTA 391 Q+ C PN CLN G CQ+ + + C C PGF G C R + C CGPG C + Sbjct: 808 QDINDCDPNPCLNGGSCQDGVGS--FSCSCLPGFAGPRCARDVDECLSNPCGPGTCTDHV 865 Query: 392 DSYKCACPVTYTGKNCE 442 S+ C CP Y G +CE Sbjct: 866 ASFTCTCPPGYGGFHCE 882 Score = 67.3 bits (157), Expect = 3e-11 Identities = 30/72 (41%), Positives = 36/72 (50%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLCGPGKCMNTADSYKC 406 CA C N C + GY C CA GF G CDR + C P C G+C++ S+ C Sbjct: 471 CASTPCRNGAKCVDQ--PDGYECRCAEGFEGTLCDRNVDDCSPDPCHHGRCVDGIASFSC 528 Query: 407 ACPVTYTGKNCE 442 AC YTG CE Sbjct: 529 ACAPGYTGTRCE 540 Score = 65.3 bits (152), Expect = 1e-10 Identities = 30/79 (37%), Positives = 43/79 (54%), Gaps = 1/79 (1%) Frame = +2 Query: 212 QNCFTCAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLC-GPGKCMNT 388 +N C+P+ C ++G C + + + C CAPG+ G C+ + CR C GKC++ Sbjct: 504 RNVDDCSPDPC-HHGRCVDGIAS--FSCACAPGYTGTRCESQVDECRSQPCRHGGKCLDL 560 Query: 389 ADSYKCACPVTYTGKNCEV 445 D Y C CP TG NCEV Sbjct: 561 VDKYLCRCPSGTTGVNCEV 579 Score = 63.7 bits (148), Expect = 4e-10 Identities = 27/72 (37%), Positives = 40/72 (55%), Gaps = 1/72 (1%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLC-GPGKCMNTADSYK 403 CAP+ C N G C+++ + Y C C PGF G NC+ + C C G C++ ++Y Sbjct: 161 CAPSPCRNGGTCRQS-GDLTYDCACLPGFEGQNCEVNVDDCPGHRCLNGGTCVDGVNTYN 219 Query: 404 CACPVTYTGKNC 439 C CP +TG+ C Sbjct: 220 CQCPPEWTGQFC 231 Score = 58.8 bits (136), Expect = 1e-08 Identities = 29/74 (39%), Positives = 38/74 (51%), Gaps = 2/74 (2%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCR-PGLCGP-GKCMNTADSY 400 C PN C + G C+ A + VC C G+ G C + + C P CGP G C N A S+ Sbjct: 735 CTPNPCEHGGRCESAPGQLP-VCSCPQGWQGPRCQQDVDECAGPAPCGPHGICTNLAGSF 793 Query: 401 KCACPVTYTGKNCE 442 C C YTG +C+ Sbjct: 794 SCTCHGGYTGPSCD 807 Score = 58.0 bits (134), Expect = 2e-08 Identities = 27/75 (36%), Positives = 35/75 (46%), Gaps = 3/75 (4%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGL--CGP-GKCMNTADS 397 C N C + +C +C C PGF G CD+ + C G C G+C+NT S Sbjct: 315 CVSNPCHEDAICDTNPVNGRAICTCPPGFTGGACDQDVDECSIGANPCEHLGRCVNTQGS 374 Query: 398 YKCACPVTYTGKNCE 442 + C C YTG CE Sbjct: 375 FLCQCGRGYTGPRCE 389 Score = 58.0 bits (134), Expect = 2e-08 Identities = 25/74 (33%), Positives = 39/74 (52%), Gaps = 2/74 (2%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESC--RPGLCGPGKCMNTADSY 400 C+P+ C N G C + + + + CLC PG+ G +C + C RP L G G C + Sbjct: 888 CSPSSCFNGGTCVDGV--NSFSCLCRPGYTGAHCQHEADPCLSRPCLHG-GVCSAAHPGF 944 Query: 401 KCACPVTYTGKNCE 442 +C C ++TG C+ Sbjct: 945 RCTCLESFTGPQCQ 958 Score = 57.6 bits (133), Expect = 3e-08 Identities = 28/78 (35%), Positives = 39/78 (50%), Gaps = 6/78 (7%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCD------RIGESCRPGLCGPGKCMNT 388 C + C + C + ++C C PG+ G +C R+GE CR G G C+NT Sbjct: 83 CLSSPCAHGARCSVG-PDGRFLCSCPPGYQGRSCRSDVDECRVGEPCRHG----GTCLNT 137 Query: 389 ADSYKCACPVTYTGKNCE 442 S++C CP YTG CE Sbjct: 138 PGSFRCQCPAGYTGPLCE 155 Score = 57.6 bits (133), Expect = 3e-08 Identities = 29/92 (31%), Positives = 42/92 (45%), Gaps = 5/92 (5%) Frame = +2 Query: 242 CLNNGVCQEALTEH--GYVCLCAPGFGGNNCDRIGESCRPGLC-GPGKCMNTADSYKCAC 412 CL+N T+H + C C PG+GG +C++ C P C G C++ +S+ C C Sbjct: 851 CLSNPCGPGTCTDHVASFTCTCPPGYGGFHCEQDLPDCSPSSCFNGGTCVDGVNSFSCLC 910 Query: 413 PVTYTGKNC--EVKQLIEYPAFTGSA*LAIKP 502 YTG +C E + P G A P Sbjct: 911 RPGYTGAHCQHEADPCLSRPCLHGGVCSAAHP 942 Score = 57.2 bits (132), Expect = 3e-08 Identities = 24/73 (32%), Positives = 38/73 (52%), Gaps = 1/73 (1%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLCGPG-KCMNTADSYK 403 C + C+N GVC++ + +G+ C C GF G+ C + C C G KC++ D Y+ Sbjct: 433 CQSSPCVNGGVCKDRV--NGFSCTCPSGFSGSTCQLDVDECASTPCRNGAKCVDQPDGYE 490 Query: 404 CACPVTYTGKNCE 442 C C + G C+ Sbjct: 491 CRCAEGFEGTLCD 503 Score = 54.8 bits (126), Expect = 2e-07 Identities = 24/76 (31%), Positives = 37/76 (48%), Gaps = 1/76 (1%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLC-GPGKCMNTADSYK 403 C C + G C+ + GY+C C PG+ G+NC+ + C C G C++ Y Sbjct: 1048 CLAQPCQHGGTCRGYMG--GYMCECLPGYNGDNCEDDVDECASQPCQHGGSCIDLVARYL 1105 Query: 404 CACPVTYTGKNCEVKQ 451 C+CP G CE+ + Sbjct: 1106 CSCPPGTLGVLCEINE 1121 Score = 51.2 bits (117), Expect = 2e-06 Identities = 27/85 (31%), Positives = 39/85 (45%), Gaps = 4/85 (4%) Frame = +2 Query: 197 EKENVQ-NCFTCAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCR--PGLC- 364 E +N + N C + CLN G C + + Y C C P + G C + C+ P C Sbjct: 189 EGQNCEVNVDDCPGHRCLNGGTCVDGVNT--YNCQCPPEWTGQFCTEDVDECQLQPNACH 246 Query: 365 GPGKCMNTADSYKCACPVTYTGKNC 439 G C NT + C C +TG++C Sbjct: 247 NGGTCFNTLGGHSCVCVNGWTGESC 271 Score = 50.8 bits (116), Expect = 3e-06 Identities = 27/80 (33%), Positives = 37/80 (46%), Gaps = 8/80 (10%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGL---CGP-----GKCM 382 CA C + G C + + Y+C C PG G C+ + C PG GP G C+ Sbjct: 1086 CASQPCQHGGSCIDLVAR--YLCSCPPGTLGVLCEINEDDCGPGPPLDSGPRCLHNGTCV 1143 Query: 383 NTADSYKCACPVTYTGKNCE 442 + ++C CP YTG CE Sbjct: 1144 DLVGGFRCTCPPGYTGLRCE 1163 Score = 50.4 bits (115), Expect = 4e-06 Identities = 25/75 (33%), Positives = 34/75 (45%), Gaps = 4/75 (5%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHG---YVCLCAPGFGGNNCDRIGESCRPGLCGPG-KCMNTAD 394 C C + G C+ + G + C CA F G C+R+ SCR C G C T Sbjct: 1210 CESQPCQHGGQCRPSPGPGGGLTFTCHCAQPFWGPRCERVARSCRELQCPVGVPCQQTPR 1269 Query: 395 SYKCACPVTYTGKNC 439 +CACP +G +C Sbjct: 1270 GPRCACPPGLSGPSC 1284 Score = 50.0 bits (114), Expect = 5e-06 Identities = 25/77 (32%), Positives = 38/77 (49%), Gaps = 1/77 (1%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLC-GPGKCMNTADSYK 403 C CL+ GVC A G+ C C F G C + + C C G+C+ T +Y Sbjct: 926 CLSRPCLHGGVCSAA--HPGFRCTCLESFTGPQCQTLVDWCSRQPCQNGGRCVQTG-AY- 981 Query: 404 CACPVTYTGKNCEVKQL 454 C CP ++G+ C+++ L Sbjct: 982 CLCPPGWSGRLCDIRSL 998 Score = 49.6 bits (113), Expect = 7e-06 Identities = 19/74 (25%), Positives = 34/74 (45%), Gaps = 1/74 (1%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLC-GPGKCMNTADSYK 403 C C N C + + + + C+C GF G C+ + C+ C G C + + + Sbjct: 395 CLSGPCRNQATCLDRIGQ--FTCICMAGFTGTYCEVDIDECQSSPCVNGGVCKDRVNGFS 452 Query: 404 CACPVTYTGKNCEV 445 C CP ++G C++ Sbjct: 453 CTCPSGFSGSTCQL 466 Score = 49.6 bits (113), Expect = 7e-06 Identities = 24/68 (35%), Positives = 34/68 (50%), Gaps = 1/68 (1%) Frame = +2 Query: 215 NCFTCAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLCGP-GKCMNTA 391 N CA N C GVC++ + Y C+C PGF G C+ C CG G C++ Sbjct: 580 NIDDCASNPC-TFGVCRDGINR--YDCVCQPGFTGPLCNVEINECASSPCGEGGSCVDGE 636 Query: 392 DSYKCACP 415 + ++C CP Sbjct: 637 NGFRCLCP 644 Score = 49.2 bits (112), Expect = 9e-06 Identities = 27/84 (32%), Positives = 37/84 (44%), Gaps = 2/84 (2%) Frame = +2 Query: 200 KENVQNCFTCAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLC-GPGK 376 + +V C P C + G C T + C C G+ G C+ C P C G Sbjct: 116 RSDVDECRVGEP--CRHGGTCLN--TPGSFRCQCPAGYTGPLCENPAVPCAPSPCRNGGT 171 Query: 377 CMNTAD-SYKCACPVTYTGKNCEV 445 C + D +Y CAC + G+NCEV Sbjct: 172 CRQSGDLTYDCACLPGFEGQNCEV 195 Score = 47.6 bits (108), Expect = 3e-05 Identities = 22/74 (29%), Positives = 33/74 (44%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLCGPGKCMNTADSYKC 406 C C + G C + + + Y+C C G G NC+ + C C G C + + Y C Sbjct: 546 CRSQPCRHGGKCLDLVDK--YLCRCPSGTTGVNCEVNIDDCASNPCTFGVCRDGINRYDC 603 Query: 407 ACPVTYTGKNCEVK 448 C +TG C V+ Sbjct: 604 VCQPGFTGPLCNVE 617 Score = 47.2 bits (107), Expect = 4e-05 Identities = 23/76 (30%), Positives = 37/76 (48%), Gaps = 3/76 (3%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDR--IGESCRPGLC-GPGKCMNTADS 397 CA C ++G+C +A G+ C+C PG+ G C + ++C C G C + Sbjct: 659 CAHEPC-SHGICYDA--PGGFRCVCEPGWSGPRCSQSLARDACESQPCRAGGTCSSDGMG 715 Query: 398 YKCACPVTYTGKNCEV 445 + C CP G+ CE+ Sbjct: 716 FHCTCPPGVQGRQCEL 731 Score = 47.2 bits (107), Expect = 4e-05 Identities = 28/83 (33%), Positives = 36/83 (43%), Gaps = 11/83 (13%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPG----------LC-GPG 373 C+ C N G C + G CLC PG+ G CD CR LC G Sbjct: 964 CSRQPCQNGGRCVQT----GAYCLCPPGWSGRLCDIRSLPCREAAAQIGVRLEQLCQAGG 1019 Query: 374 KCMNTADSYKCACPVTYTGKNCE 442 +C++ S+ C CP TG +CE Sbjct: 1020 QCVDEDSSHYCVCPEGRTGSHCE 1042 Score = 47.2 bits (107), Expect = 4e-05 Identities = 21/71 (29%), Positives = 34/71 (47%), Gaps = 4/71 (5%) Frame = +2 Query: 242 CLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLCGPG---KCM-NTADSYKCA 409 CL+NG C + + G+ C C PG+ G C+ CR G C C+ + ++C Sbjct: 1136 CLHNGTCVDLVG--GFRCTCPPGYTGLRCEADINECRSGACHAAHTRDCLQDPGGGFRCL 1193 Query: 410 CPVTYTGKNCE 442 C ++G C+ Sbjct: 1194 CHAGFSGPRCQ 1204 Score = 46.8 bits (106), Expect = 5e-05 Identities = 26/97 (26%), Positives = 43/97 (44%), Gaps = 3/97 (3%) Frame = +2 Query: 200 KENVQNCFTCAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLC-GPGK 376 +++V C AP C +G+C + C C G+ G +CD+ C P C G Sbjct: 768 QQDVDECAGPAP--CGPHGICTNLAGS--FSCTCHGGYTGPSCDQDINDCDPNPCLNGGS 823 Query: 377 CMNTADSYKCACPVTYTGKNC--EVKQLIEYPAFTGS 481 C + S+ C+C + G C +V + + P G+ Sbjct: 824 CQDGVGSFSCSCLPGFAGPRCARDVDECLSNPCGPGT 860 Score = 46.0 bits (104), Expect = 8e-05 Identities = 23/82 (28%), Positives = 36/82 (43%), Gaps = 1/82 (1%) Frame = +2 Query: 203 ENVQNCFTCAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLC-GPGKC 379 ++V C + N C + G C T+ ++C C G+ G C+ C G C C Sbjct: 350 QDVDEC-SIGANPCEHLGRCVN--TQGSFLCQCGRGYTGPRCETDVNECLSGPCRNQATC 406 Query: 380 MNTADSYKCACPVTYTGKNCEV 445 ++ + C C +TG CEV Sbjct: 407 LDRIGQFTCICMAGFTGTYCEV 428 Score = 45.2 bits (102), Expect = 1e-04 Identities = 23/73 (31%), Positives = 35/73 (47%), Gaps = 5/73 (6%) Frame = +2 Query: 242 CLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLC-GPGKCMNTADS----YKC 406 C N G C + L CLC PG+ G C ++ + C G C G G C ++ + + C Sbjct: 9 CANGGRCTQ-LPSREAACLCPPGWVGERC-QLEDPCHSGPCAGRGVCQSSVVAGTARFSC 66 Query: 407 ACPVTYTGKNCEV 445 CP + G +C + Sbjct: 67 RCPRGFRGPDCSL 79 Score = 44.4 bits (100), Expect = 3e-04 Identities = 21/71 (29%), Positives = 30/71 (42%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLCGPGKCMNTADSYKC 406 CA + C G C + E+G+ CLC PG C C C G C + ++C Sbjct: 621 CASSPCGEGGSCVDG--ENGFRCLCPPGSLPPLCLPPSHPCAHEPCSHGICYDAPGGFRC 678 Query: 407 ACPVTYTGKNC 439 C ++G C Sbjct: 679 VCEPGWSGPRC 689 Score = 43.2 bits (97), Expect = 6e-04 Identities = 22/69 (31%), Positives = 30/69 (43%), Gaps = 1/69 (1%) Frame = +2 Query: 239 LCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLC-GPGKCMNTADSYKCACP 415 LC G C + + H C+C G G++C++ + C C G C Y C C Sbjct: 1014 LCQAGGQCVDEDSSH--YCVCPEGRTGSHCEQEVDPCLAQPCQHGGTCRGYMGGYMCECL 1071 Query: 416 VTYTGKNCE 442 Y G NCE Sbjct: 1072 PGYNGDNCE 1080 Score = 34.3 bits (75), Expect = 0.27 Identities = 17/59 (28%), Positives = 22/59 (37%), Gaps = 6/59 (10%) Frame = +2 Query: 284 GYVCLCAPGFGGNNCDRIGESCRP------GLCGPGKCMNTADSYKCACPVTYTGKNCE 442 G+ CLC GF G C + C G C P ++ C C + G CE Sbjct: 1189 GFRCLCHAGFSGPRCQTVLSPCESQPCQHGGQCRPSPGPGGGLTFTCHCAQPFWGPRCE 1247 Score = 33.5 bits (73), Expect = 0.48 Identities = 25/85 (29%), Positives = 33/85 (38%), Gaps = 12/85 (14%) Frame = +2 Query: 224 TCAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGL----CGPGKCMN-- 385 +C C CQ+ T G C C PG G +C R PG C C++ Sbjct: 1252 SCRELQCPVGVPCQQ--TPRGPRCACPPGLSGPSC-RSFPGSPPGASNASCAAAPCLHGG 1308 Query: 386 ------TADSYKCACPVTYTGKNCE 442 A ++CAC +TG CE Sbjct: 1309 SCRPAPLAPFFRCACAQGWTGPRCE 1333 >BC146759-1|AAI46760.1| 1523|Homo sapiens slit homolog 3 (Drosophila) protein. Length = 1523 Score = 73.3 bits (172), Expect = 5e-13 Identities = 46/137 (33%), Positives = 67/137 (48%), Gaps = 6/137 (4%) Frame = +2 Query: 56 LNQPLYIGGVPDFDQLPIDLAGAS----GFVGCISMLILGNEEKNIMALALEKENVQ-NC 220 +N PLY+GG+P L G GF GCI + + NE ++ AL + V C Sbjct: 1273 INSPLYLGGIPTSTGLSALRQGTDRPLGGFHGCIHEVRINNELQDFKALPPQSLGVSPGC 1332 Query: 221 FTCAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIG-ESCRPGLCGPGKCMNTADS 397 +C +C +G+C+ ++ + VC C PG+ G CD+ + C C GKC+ T S Sbjct: 1333 KSCT--VC-KHGLCR-SVEKDSVVCECRPGWTGPLCDQEARDPCLGHRCHHGKCVATGTS 1388 Query: 398 YKCACPVTYTGKNCEVK 448 Y C C Y G C+ K Sbjct: 1389 YMCKCAEGYGGDLCDNK 1405 Score = 58.0 bits (134), Expect = 2e-08 Identities = 27/75 (36%), Positives = 37/75 (49%), Gaps = 3/75 (4%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRP--GLC-GPGKCMNTADS 397 C N C NN C + + + YVC+C P + G CD + + C P LC KC+ Sbjct: 1000 CEDNDCENNATCVDGI--NNYVCICPPNYTGELCDEVIDHCVPELNLCQHEAKCIPLDKG 1057 Query: 398 YKCACPVTYTGKNCE 442 + C C Y+GK CE Sbjct: 1058 FSCECVPGYSGKLCE 1072 Score = 54.8 bits (126), Expect = 2e-07 Identities = 25/75 (33%), Positives = 37/75 (49%), Gaps = 3/75 (4%) Frame = +2 Query: 227 CAP--NLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLCGPG-KCMNTADS 397 C P NLC + C + G+ C C PG+ G C+ + C C G +C++T + Sbjct: 1038 CVPELNLCQHEAKCIPL--DKGFSCECVPGYSGKLCETDNDDCVAHKCRHGAQCVDTING 1095 Query: 398 YKCACPVTYTGKNCE 442 Y C CP ++G CE Sbjct: 1096 YTCTCPQGFSGPFCE 1110 Score = 52.4 bits (120), Expect = 1e-06 Identities = 26/83 (31%), Positives = 39/83 (46%), Gaps = 4/83 (4%) Frame = +2 Query: 209 VQNCFTCAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLCGPGKCMNT 388 V C C + C NNG C + E Y C C + G +C +C C G + Sbjct: 914 VAKCNACLSSPCKNNGTCTQDPVEL-YRCACPYSYKGKDCTVPINTCIQNPCQHGGTCHL 972 Query: 389 ADSYK----CACPVTYTGKNCEV 445 +DS+K C+CP+ + G+ CE+ Sbjct: 973 SDSHKDGFSCSCPLGFEGQRCEI 995 Score = 42.3 bits (95), Expect = 0.001 Identities = 23/76 (30%), Positives = 38/76 (50%), Gaps = 4/76 (5%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGES---CRPGLCGPGKC-MNTAD 394 C + C ++G C T Y+C CA G+GG+ CD +S C C G+C ++ Sbjct: 1372 CLGHRC-HHGKC--VATGTSYMCKCAEGYGGDLCDNKNDSANACSAFKCHHGQCHISDQG 1428 Query: 395 SYKCACPVTYTGKNCE 442 C C ++G++C+ Sbjct: 1429 EPYCLCQPGFSGEHCQ 1444 Score = 36.3 bits (80), Expect = 0.068 Identities = 21/80 (26%), Positives = 30/80 (37%), Gaps = 8/80 (10%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESC--RPGLCGPGKCMNTADSY 400 C + C + C + + +GY C C GF G C+ + C +C N A Sbjct: 1078 CVAHKCRHGAQCVDTI--NGYTCTCPQGFSGPFCEHPPPMVLLQTSPCDQYECQNGAQCI 1135 Query: 401 ------KCACPVTYTGKNCE 442 C CP + G CE Sbjct: 1136 VVQQEPTCRCPPGFAGPRCE 1155 >BC063620-1|AAH63620.1| 488|Homo sapiens AGRN protein protein. Length = 488 Score = 73.3 bits (172), Expect = 5e-13 Identities = 43/114 (37%), Positives = 59/114 (51%), Gaps = 6/114 (5%) Frame = +2 Query: 11 GP-FIAESPDQWTVLELNQPLYIGGVPDFDQLPIDLAGASGFVGCISMLILGNEEKNIMA 187 GP + ESP TVL L +PLY+GG PDF +L A +SGF G I ++ LG + Sbjct: 186 GPRVLGESPVPHTVLNLKEPLYVGGAPDFSKLARAAAVSSGFDGAIQLVSLGGRQLLTPE 245 Query: 188 LALEKENVQN-----CFTCAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDR 334 L + +V + C + + CLN C E YVCLC GF G +C++ Sbjct: 246 HVLRQVDVTSFAGHPCTRASGHPCLNGASC--VPREAAYVCLCPGGFSGPHCEK 297 Score = 41.9 bits (94), Expect = 0.001 Identities = 22/75 (29%), Positives = 40/75 (53%), Gaps = 1/75 (1%) Frame = +2 Query: 5 NSGPFIAESPDQWTVLELNQPLYIGGVPDFDQLP-IDLAGASGFVGCISMLILGNEEKNI 181 N P SP T L+ + L++GG+P+ P + A +GFVGC+ +++G ++ Sbjct: 413 NEAPVTGSSPLGATQLDTDGALWLGGLPELPVGPALPKAYGTGFVGCLRDVVVGRHPLHL 472 Query: 182 MALALEKENVQNCFT 226 + A+ K ++ C T Sbjct: 473 LEDAVTKPELRPCPT 487 Score = 33.1 bits (72), Expect = 0.63 Identities = 20/69 (28%), Positives = 26/69 (37%), Gaps = 2/69 (2%) Frame = +2 Query: 242 CLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLC-GPGKCMNTAD-SYKCACP 415 C CQ L + C C PG G C C+P C G C + +C CP Sbjct: 1 CHGGAPCQN-LEAGRFHCQCPPGRVGPTCADEKSPCQPNPCHGAAPCRVLPEGGAQCECP 59 Query: 416 VTYTGKNCE 442 + G C+ Sbjct: 60 LGREGTFCQ 68 Score = 31.9 bits (69), Expect = 1.5 Identities = 20/53 (37%), Positives = 27/53 (50%) Frame = +2 Query: 311 FGGNNCDRIGESCRPGLCGPGKCMNTADSYKCACPVTYTGKNCEVKQLIEYPA 469 F G+ C R S P L G C+ +Y C CP ++G +CE K L+E A Sbjct: 256 FAGHPCTRA--SGHPCLNG-ASCVPREAAYVCLCPGGFSGPHCE-KGLVEKSA 304 >BC007649-1|AAH07649.1| 488|Homo sapiens AGRN protein protein. Length = 488 Score = 73.3 bits (172), Expect = 5e-13 Identities = 43/114 (37%), Positives = 59/114 (51%), Gaps = 6/114 (5%) Frame = +2 Query: 11 GP-FIAESPDQWTVLELNQPLYIGGVPDFDQLPIDLAGASGFVGCISMLILGNEEKNIMA 187 GP + ESP TVL L +PLY+GG PDF +L A +SGF G I ++ LG + Sbjct: 186 GPRVLGESPVPHTVLNLKEPLYVGGAPDFSKLARAAAVSSGFDGAIQLVSLGGRQLLTPE 245 Query: 188 LALEKENVQN-----CFTCAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDR 334 L + +V + C + + CLN C E YVCLC GF G +C++ Sbjct: 246 HVLRQVDVTSFAGHPCTRASGHPCLNGASC--VPREAAYVCLCPGGFSGPHCEK 297 Score = 41.9 bits (94), Expect = 0.001 Identities = 22/75 (29%), Positives = 40/75 (53%), Gaps = 1/75 (1%) Frame = +2 Query: 5 NSGPFIAESPDQWTVLELNQPLYIGGVPDFDQLP-IDLAGASGFVGCISMLILGNEEKNI 181 N P SP T L+ + L++GG+P+ P + A +GFVGC+ +++G ++ Sbjct: 413 NEAPVTGSSPLGATQLDTDGALWLGGLPELPVGPALPKAYGTGFVGCLRDVVVGRHPLHL 472 Query: 182 MALALEKENVQNCFT 226 + A+ K ++ C T Sbjct: 473 LEDAVTKPELRPCPT 487 Score = 33.1 bits (72), Expect = 0.63 Identities = 20/69 (28%), Positives = 26/69 (37%), Gaps = 2/69 (2%) Frame = +2 Query: 242 CLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLC-GPGKCMNTAD-SYKCACP 415 C CQ L + C C PG G C C+P C G C + +C CP Sbjct: 1 CHGGAPCQN-LEAGRFHCQCPPGRVGPTCADEKSPCQPNPCHGAAPCRVLPEGGAQCECP 59 Query: 416 VTYTGKNCE 442 + G C+ Sbjct: 60 LGREGTFCQ 68 Score = 31.9 bits (69), Expect = 1.5 Identities = 20/53 (37%), Positives = 27/53 (50%) Frame = +2 Query: 311 FGGNNCDRIGESCRPGLCGPGKCMNTADSYKCACPVTYTGKNCEVKQLIEYPA 469 F G+ C R S P L G C+ +Y C CP ++G +CE K L+E A Sbjct: 256 FAGHPCTRA--SGHPCLNG-ASCVPREAAYVCLCPGGFSGPHCE-KGLVEKSA 304 >AY358884-1|AAQ89243.1| 1523|Homo sapiens SLIT3 protein. Length = 1523 Score = 73.3 bits (172), Expect = 5e-13 Identities = 46/137 (33%), Positives = 67/137 (48%), Gaps = 6/137 (4%) Frame = +2 Query: 56 LNQPLYIGGVPDFDQLPIDLAGAS----GFVGCISMLILGNEEKNIMALALEKENVQ-NC 220 +N PLY+GG+P L G GF GCI + + NE ++ AL + V C Sbjct: 1273 INSPLYLGGIPTSTGLSALRQGTDRPLGGFHGCIHEVRINNELQDFKALPPQSLGVSPGC 1332 Query: 221 FTCAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIG-ESCRPGLCGPGKCMNTADS 397 +C +C +G+C+ ++ + VC C PG+ G CD+ + C C GKC+ T S Sbjct: 1333 KSCT--VC-KHGLCR-SVEKDSVVCECRPGWTGPLCDQEARDPCLGHRCHHGKCVATGTS 1388 Query: 398 YKCACPVTYTGKNCEVK 448 Y C C Y G C+ K Sbjct: 1389 YMCKCAEGYGGDLCDNK 1405 Score = 58.0 bits (134), Expect = 2e-08 Identities = 27/75 (36%), Positives = 37/75 (49%), Gaps = 3/75 (4%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRP--GLC-GPGKCMNTADS 397 C N C NN C + + + YVC+C P + G CD + + C P LC KC+ Sbjct: 1000 CEDNDCENNATCVDGI--NNYVCICPPNYTGELCDEVIDHCVPELNLCQHEAKCIPLDKG 1057 Query: 398 YKCACPVTYTGKNCE 442 + C C Y+GK CE Sbjct: 1058 FSCECVPGYSGKLCE 1072 Score = 54.8 bits (126), Expect = 2e-07 Identities = 25/75 (33%), Positives = 37/75 (49%), Gaps = 3/75 (4%) Frame = +2 Query: 227 CAP--NLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLCGPG-KCMNTADS 397 C P NLC + C + G+ C C PG+ G C+ + C C G +C++T + Sbjct: 1038 CVPELNLCQHEAKCIPL--DKGFSCECVPGYSGKLCETDNDDCVAHKCRHGAQCVDTING 1095 Query: 398 YKCACPVTYTGKNCE 442 Y C CP ++G CE Sbjct: 1096 YTCTCPQGFSGPFCE 1110 Score = 52.4 bits (120), Expect = 1e-06 Identities = 26/83 (31%), Positives = 39/83 (46%), Gaps = 4/83 (4%) Frame = +2 Query: 209 VQNCFTCAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLCGPGKCMNT 388 V C C + C NNG C + E Y C C + G +C +C C G + Sbjct: 914 VAKCNACLSSPCKNNGTCTQDPVEL-YRCACPYSYKGKDCTVPINTCIQNPCQHGGTCHL 972 Query: 389 ADSYK----CACPVTYTGKNCEV 445 +DS+K C+CP+ + G+ CE+ Sbjct: 973 SDSHKDGFSCSCPLGFEGQRCEI 995 Score = 42.3 bits (95), Expect = 0.001 Identities = 23/76 (30%), Positives = 38/76 (50%), Gaps = 4/76 (5%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGES---CRPGLCGPGKC-MNTAD 394 C + C ++G C T Y+C CA G+GG+ CD +S C C G+C ++ Sbjct: 1372 CLGHRC-HHGKC--VATGTSYMCKCAEGYGGDLCDNKNDSANACSAFKCHHGQCHISDQG 1428 Query: 395 SYKCACPVTYTGKNCE 442 C C ++G++C+ Sbjct: 1429 EPYCLCQPGFSGEHCQ 1444 Score = 36.3 bits (80), Expect = 0.068 Identities = 21/80 (26%), Positives = 30/80 (37%), Gaps = 8/80 (10%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESC--RPGLCGPGKCMNTADSY 400 C + C + C + + +GY C C GF G C+ + C +C N A Sbjct: 1078 CVAHKCRHGAQCVDTI--NGYTCTCPQGFSGPFCEHPPPMVLLQTSPCDQYECQNGAQCI 1135 Query: 401 ------KCACPVTYTGKNCE 442 C CP + G CE Sbjct: 1136 VVQQEPTCRCPPGFAGPRCE 1155 >AL645608-13|CAI15575.2| 2045|Homo sapiens agrin protein. Length = 2045 Score = 73.3 bits (172), Expect = 5e-13 Identities = 43/114 (37%), Positives = 59/114 (51%), Gaps = 6/114 (5%) Frame = +2 Query: 11 GP-FIAESPDQWTVLELNQPLYIGGVPDFDQLPIDLAGASGFVGCISMLILGNEEKNIMA 187 GP + ESP TVL L +PLY+GG PDF +L A +SGF G I ++ LG + Sbjct: 1743 GPRVLGESPVPHTVLNLKEPLYVGGAPDFSKLARAAAVSSGFDGAIQLVSLGGRQLLTPE 1802 Query: 188 LALEKENVQN-----CFTCAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDR 334 L + +V + C + + CLN C E YVCLC GF G +C++ Sbjct: 1803 HVLRQVDVTSFAGHPCTRASGHPCLNGASC--VPREAAYVCLCPGGFSGPHCEK 1854 Score = 64.5 bits (150), Expect = 2e-10 Identities = 47/157 (29%), Positives = 64/157 (40%), Gaps = 10/157 (6%) Frame = +2 Query: 2 DNSGPFIAESPDQWTVLELNQPLYIGGVPDFDQLPIDLAG---ASGFVGCISMLILGNEE 172 D P + ESP L L+ L++GGVP+ DQ + L +G GCI +L + N+ Sbjct: 1471 DGETPVLGESPSGTDGLNLDTDLFVGGVPE-DQAAVALERTFVGAGLRGCIRLLDVNNQR 1529 Query: 173 KNI---MALALEKENVQNC--FTCAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRI 337 + A V C C PN C CQ L + C C PG G C Sbjct: 1530 LELGIGPGAATRGSGVGECGDHPCLPNPCHGGAPCQN-LEAGRFHCQCPPGRVGPTCADE 1588 Query: 338 GESCRPGLC-GPGKCMNTAD-SYKCACPVTYTGKNCE 442 C+P C G C + +C CP+ G C+ Sbjct: 1589 KSPCQPNPCHGAAPCRVLPEGGAQCECPLGREGTFCQ 1625 Score = 41.9 bits (94), Expect = 0.001 Identities = 22/75 (29%), Positives = 40/75 (53%), Gaps = 1/75 (1%) Frame = +2 Query: 5 NSGPFIAESPDQWTVLELNQPLYIGGVPDFDQLP-IDLAGASGFVGCISMLILGNEEKNI 181 N P SP T L+ + L++GG+P+ P + A +GFVGC+ +++G ++ Sbjct: 1970 NEAPVTGSSPLGATQLDTDGALWLGGLPELPVGPALPKAYGTGFVGCLRDVVVGRHPLHL 2029 Query: 182 MALALEKENVQNCFT 226 + A+ K ++ C T Sbjct: 2030 LEDAVTKPELRPCPT 2044 Score = 34.3 bits (75), Expect = 0.27 Identities = 12/37 (32%), Positives = 18/37 (48%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRI 337 C C + G CQ+ G+ C C G GG C+++ Sbjct: 1333 CDSQPCFHGGTCQDWALGGGFTCSCPAGRGGAVCEKV 1369 Score = 31.9 bits (69), Expect = 1.5 Identities = 20/53 (37%), Positives = 27/53 (50%) Frame = +2 Query: 311 FGGNNCDRIGESCRPGLCGPGKCMNTADSYKCACPVTYTGKNCEVKQLIEYPA 469 F G+ C R S P L G C+ +Y C CP ++G +CE K L+E A Sbjct: 1813 FAGHPCTRA--SGHPCLNG-ASCVPREAAYVCLCPGGFSGPHCE-KGLVEKSA 1861 >AF075240-1|AAD19336.1| 850|Homo sapiens SLIT1 protein protein. Length = 850 Score = 73.3 bits (172), Expect = 5e-13 Identities = 46/137 (33%), Positives = 67/137 (48%), Gaps = 6/137 (4%) Frame = +2 Query: 56 LNQPLYIGGVPDFDQLPIDLAGAS----GFVGCISMLILGNEEKNIMALALEKENVQ-NC 220 +N PLY+GG+P L G GF GCI + + NE ++ AL + V C Sbjct: 600 INSPLYLGGIPTSTGLSALRQGTDRPLGGFHGCIHEVRINNELQDFKALPPQSLGVSPGC 659 Query: 221 FTCAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIG-ESCRPGLCGPGKCMNTADS 397 +C +C +G+C+ ++ + VC C PG+ G CD+ + C C GKC+ T S Sbjct: 660 KSCT--VC-KHGLCR-SVEKDSVVCECRPGWTGPLCDQEARDPCLGHRCHHGKCVATGTS 715 Query: 398 YKCACPVTYTGKNCEVK 448 Y C C Y G C+ K Sbjct: 716 YMCKCAEGYGGDLCDNK 732 Score = 58.0 bits (134), Expect = 2e-08 Identities = 27/75 (36%), Positives = 37/75 (49%), Gaps = 3/75 (4%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRP--GLC-GPGKCMNTADS 397 C N C NN C + + + YVC+C P + G CD + + C P LC KC+ Sbjct: 427 CEDNDCENNATCVDGI--NNYVCICPPNYTGELCDEVIDHCVPELNLCQHEAKCIPLDKG 484 Query: 398 YKCACPVTYTGKNCE 442 + C C Y+GK CE Sbjct: 485 FSCECVPGYSGKLCE 499 Score = 54.8 bits (126), Expect = 2e-07 Identities = 25/75 (33%), Positives = 37/75 (49%), Gaps = 3/75 (4%) Frame = +2 Query: 227 CAP--NLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLCGPG-KCMNTADS 397 C P NLC + C + G+ C C PG+ G C+ + C C G +C++T + Sbjct: 465 CVPELNLCQHEAKCIPL--DKGFSCECVPGYSGKLCETDNDDCVAHKCRHGAQCVDTING 522 Query: 398 YKCACPVTYTGKNCE 442 Y C CP ++G CE Sbjct: 523 YTCTCPQGFSGPFCE 537 Score = 52.4 bits (120), Expect = 1e-06 Identities = 26/83 (31%), Positives = 39/83 (46%), Gaps = 4/83 (4%) Frame = +2 Query: 209 VQNCFTCAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLCGPGKCMNT 388 V C C + C NNG C + E Y C C + G +C +C C G + Sbjct: 341 VAKCNACLSSPCKNNGTCTQDPVEL-YRCACPYSYKGKDCTVPINTCIQNPCQHGGTCHL 399 Query: 389 ADSYK----CACPVTYTGKNCEV 445 +DS+K C+CP+ + G+ CE+ Sbjct: 400 SDSHKDGFSCSCPLGFEGQRCEI 422 Score = 42.3 bits (95), Expect = 0.001 Identities = 23/76 (30%), Positives = 38/76 (50%), Gaps = 4/76 (5%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGES---CRPGLCGPGKC-MNTAD 394 C + C ++G C T Y+C CA G+GG+ CD +S C C G+C ++ Sbjct: 699 CLGHRC-HHGKC--VATGTSYMCKCAEGYGGDLCDNKNDSANACSAFKCHHGQCHISDQG 755 Query: 395 SYKCACPVTYTGKNCE 442 C C ++G++C+ Sbjct: 756 EPYCLCQPGFSGEHCQ 771 >AF016903-1|AAC39776.1| 2026|Homo sapiens agrin precursor protein. Length = 2026 Score = 73.3 bits (172), Expect = 5e-13 Identities = 43/114 (37%), Positives = 59/114 (51%), Gaps = 6/114 (5%) Frame = +2 Query: 11 GP-FIAESPDQWTVLELNQPLYIGGVPDFDQLPIDLAGASGFVGCISMLILGNEEKNIMA 187 GP + ESP TVL L +PLY+GG PDF +L A +SGF G I ++ LG + Sbjct: 1724 GPRVLGESPVPHTVLNLKEPLYVGGAPDFSKLARAAAVSSGFDGAIQLVSLGGRQLLTPE 1783 Query: 188 LALEKENVQN-----CFTCAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDR 334 L + +V + C + + CLN C E YVCLC GF G +C++ Sbjct: 1784 HVLRQVDVTSFAGHPCTRASGHPCLNGASC--VPREAAYVCLCPGGFSGPHCEK 1835 Score = 64.5 bits (150), Expect = 2e-10 Identities = 47/157 (29%), Positives = 64/157 (40%), Gaps = 10/157 (6%) Frame = +2 Query: 2 DNSGPFIAESPDQWTVLELNQPLYIGGVPDFDQLPIDLAG---ASGFVGCISMLILGNEE 172 D P + ESP L L+ L++GGVP+ DQ + L +G GCI +L + N+ Sbjct: 1452 DGETPVLGESPSGTDGLNLDTDLFVGGVPE-DQAAVALERTFVGAGLRGCIRLLDVNNQR 1510 Query: 173 KNI---MALALEKENVQNC--FTCAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRI 337 + A V C C PN C CQ L + C C PG G C Sbjct: 1511 LELGIGPGAATRGSGVGECGDHPCLPNPCHGGAPCQN-LEAGRFHCQCPPGRVGPTCADE 1569 Query: 338 GESCRPGLC-GPGKCMNTAD-SYKCACPVTYTGKNCE 442 C+P C G C + +C CP+ G C+ Sbjct: 1570 KSPCQPNPCHGAAPCRVLPEGGAQCECPLGREGTFCQ 1606 Score = 41.9 bits (94), Expect = 0.001 Identities = 22/75 (29%), Positives = 40/75 (53%), Gaps = 1/75 (1%) Frame = +2 Query: 5 NSGPFIAESPDQWTVLELNQPLYIGGVPDFDQLP-IDLAGASGFVGCISMLILGNEEKNI 181 N P SP T L+ + L++GG+P+ P + A +GFVGC+ +++G ++ Sbjct: 1951 NEAPVTGSSPLGATQLDTDGALWLGGLPELPVGPALPKAYGTGFVGCLRDVVVGRHPLHL 2010 Query: 182 MALALEKENVQNCFT 226 + A+ K ++ C T Sbjct: 2011 LEDAVTKPELRPCPT 2025 Score = 34.3 bits (75), Expect = 0.27 Identities = 12/37 (32%), Positives = 18/37 (48%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRI 337 C C + G CQ+ G+ C C G GG C+++ Sbjct: 1314 CDSQPCFHGGTCQDWALGGGFTCSCPAGRGGAVCEKV 1350 Score = 31.9 bits (69), Expect = 1.5 Identities = 20/53 (37%), Positives = 27/53 (50%) Frame = +2 Query: 311 FGGNNCDRIGESCRPGLCGPGKCMNTADSYKCACPVTYTGKNCEVKQLIEYPA 469 F G+ C R S P L G C+ +Y C CP ++G +CE K L+E A Sbjct: 1794 FAGHPCTRA--SGHPCLNG-ASCVPREAAYVCLCPGGFSGPHCE-KGLVEKSA 1842 >AB191264-1|BAD52440.1| 2045|Homo sapiens agrin protein. Length = 2045 Score = 73.3 bits (172), Expect = 5e-13 Identities = 43/114 (37%), Positives = 59/114 (51%), Gaps = 6/114 (5%) Frame = +2 Query: 11 GP-FIAESPDQWTVLELNQPLYIGGVPDFDQLPIDLAGASGFVGCISMLILGNEEKNIMA 187 GP + ESP TVL L +PLY+GG PDF +L A +SGF G I ++ LG + Sbjct: 1743 GPRVLGESPVPHTVLNLKEPLYVGGAPDFSKLARAAAVSSGFDGAIQLVSLGGRQLLTPE 1802 Query: 188 LALEKENVQN-----CFTCAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDR 334 L + +V + C + + CLN C E YVCLC GF G +C++ Sbjct: 1803 HVLRQVDVTSFAGHPCTRASGHPCLNGASC--VPREAAYVCLCPGGFSGPHCEK 1854 Score = 64.5 bits (150), Expect = 2e-10 Identities = 47/157 (29%), Positives = 64/157 (40%), Gaps = 10/157 (6%) Frame = +2 Query: 2 DNSGPFIAESPDQWTVLELNQPLYIGGVPDFDQLPIDLAG---ASGFVGCISMLILGNEE 172 D P + ESP L L+ L++GGVP+ DQ + L +G GCI +L + N+ Sbjct: 1471 DGETPVLGESPSGTDGLNLDTDLFVGGVPE-DQAAVALERTFVGAGLRGCIRLLDVNNQR 1529 Query: 173 KNI---MALALEKENVQNC--FTCAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRI 337 + A V C C PN C CQ L + C C PG G C Sbjct: 1530 LELGIGPGAATRGSGVGECGDHPCLPNPCHGGAPCQN-LEAGRFHCQCPPGRVGPTCADE 1588 Query: 338 GESCRPGLC-GPGKCMNTAD-SYKCACPVTYTGKNCE 442 C+P C G C + +C CP+ G C+ Sbjct: 1589 KSPCQPNPCHGAAPCRVLPEGGAQCECPLGREGTFCQ 1625 Score = 41.9 bits (94), Expect = 0.001 Identities = 22/75 (29%), Positives = 40/75 (53%), Gaps = 1/75 (1%) Frame = +2 Query: 5 NSGPFIAESPDQWTVLELNQPLYIGGVPDFDQLP-IDLAGASGFVGCISMLILGNEEKNI 181 N P SP T L+ + L++GG+P+ P + A +GFVGC+ +++G ++ Sbjct: 1970 NEAPVTGSSPLGATQLDTDGALWLGGLPELPVGPALPKAYGTGFVGCLRDVVVGRHPLHL 2029 Query: 182 MALALEKENVQNCFT 226 + A+ K ++ C T Sbjct: 2030 LEDAVTKPELRPCPT 2044 Score = 34.3 bits (75), Expect = 0.27 Identities = 12/37 (32%), Positives = 18/37 (48%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRI 337 C C + G CQ+ G+ C C G GG C+++ Sbjct: 1333 CDSQPCFHGGTCQDWALGGGFTCSCPAGRGGAVCEKV 1369 Score = 31.9 bits (69), Expect = 1.5 Identities = 20/53 (37%), Positives = 27/53 (50%) Frame = +2 Query: 311 FGGNNCDRIGESCRPGLCGPGKCMNTADSYKCACPVTYTGKNCEVKQLIEYPA 469 F G+ C R S P L G C+ +Y C CP ++G +CE K L+E A Sbjct: 1813 FAGHPCTRA--SGHPCLNG-ASCVPREAAYVCLCPGGFSGPHCE-KGLVEKSA 1861 >AB017169-1|BAA35186.1| 1523|Homo sapiens Slit-3 protein protein. Length = 1523 Score = 73.3 bits (172), Expect = 5e-13 Identities = 46/137 (33%), Positives = 67/137 (48%), Gaps = 6/137 (4%) Frame = +2 Query: 56 LNQPLYIGGVPDFDQLPIDLAGAS----GFVGCISMLILGNEEKNIMALALEKENVQ-NC 220 +N PLY+GG+P L G GF GCI + + NE ++ AL + V C Sbjct: 1273 INSPLYLGGIPTSTGLSALRQGTDRPLGGFHGCIHEVRINNELQDFKALPPQSLGVSPGC 1332 Query: 221 FTCAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIG-ESCRPGLCGPGKCMNTADS 397 +C +C +G+C+ ++ + VC C PG+ G CD+ + C C GKC+ T S Sbjct: 1333 KSCT--VC-KHGLCR-SVEKDSVVCECRPGWTGPLCDQEARDPCLGHRCHHGKCVATGTS 1388 Query: 398 YKCACPVTYTGKNCEVK 448 Y C C Y G C+ K Sbjct: 1389 YMCKCAEGYGGDLCDNK 1405 Score = 58.0 bits (134), Expect = 2e-08 Identities = 27/75 (36%), Positives = 37/75 (49%), Gaps = 3/75 (4%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRP--GLC-GPGKCMNTADS 397 C N C NN C + + + YVC+C P + G CD + + C P LC KC+ Sbjct: 1000 CEDNDCENNATCVDGI--NNYVCICPPNYTGELCDEVIDHCVPELNLCQHEAKCIPLDKG 1057 Query: 398 YKCACPVTYTGKNCE 442 + C C Y+GK CE Sbjct: 1058 FSCECVPGYSGKLCE 1072 Score = 54.8 bits (126), Expect = 2e-07 Identities = 25/75 (33%), Positives = 37/75 (49%), Gaps = 3/75 (4%) Frame = +2 Query: 227 CAP--NLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLCGPG-KCMNTADS 397 C P NLC + C + G+ C C PG+ G C+ + C C G +C++T + Sbjct: 1038 CVPELNLCQHEAKCIPL--DKGFSCECVPGYSGKLCETDNDDCVAHKCRHGAQCVDTING 1095 Query: 398 YKCACPVTYTGKNCE 442 Y C CP ++G CE Sbjct: 1096 YTCTCPQGFSGPFCE 1110 Score = 52.4 bits (120), Expect = 1e-06 Identities = 26/83 (31%), Positives = 39/83 (46%), Gaps = 4/83 (4%) Frame = +2 Query: 209 VQNCFTCAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLCGPGKCMNT 388 V C C + C NNG C + E Y C C + G +C +C C G + Sbjct: 914 VAKCNACLSSPCKNNGTCTQDPVEL-YRCACPYSYKGKDCTVPINTCIQNPCQHGGTCHL 972 Query: 389 ADSYK----CACPVTYTGKNCEV 445 +DS+K C+CP+ + G+ CE+ Sbjct: 973 SDSHKDGFSCSCPLGFEGQRCEI 995 Score = 42.3 bits (95), Expect = 0.001 Identities = 23/76 (30%), Positives = 38/76 (50%), Gaps = 4/76 (5%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGES---CRPGLCGPGKC-MNTAD 394 C + C ++G C T Y+C CA G+GG+ CD +S C C G+C ++ Sbjct: 1372 CLGHRC-HHGKC--VATGTSYMCKCAEGYGGDLCDNKNDSANACSAFKCHHGQCHISDQG 1428 Query: 395 SYKCACPVTYTGKNCE 442 C C ++G++C+ Sbjct: 1429 EPYCLCQPGFSGEHCQ 1444 Score = 36.3 bits (80), Expect = 0.068 Identities = 21/80 (26%), Positives = 30/80 (37%), Gaps = 8/80 (10%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESC--RPGLCGPGKCMNTADSY 400 C + C + C + + +GY C C GF G C+ + C +C N A Sbjct: 1078 CVAHKCRHGAQCVDTI--NGYTCTCPQGFSGPFCEHPPPMVLLQTSPCDQYECQNGAQCI 1135 Query: 401 ------KCACPVTYTGKNCE 442 C CP + G CE Sbjct: 1136 VVQQEPTCRCPPGFAGPRCE 1155 >AB011538-1|BAA32466.2| 1559|Homo sapiens MEGF5 protein. Length = 1559 Score = 73.3 bits (172), Expect = 5e-13 Identities = 46/137 (33%), Positives = 67/137 (48%), Gaps = 6/137 (4%) Frame = +2 Query: 56 LNQPLYIGGVPDFDQLPIDLAGAS----GFVGCISMLILGNEEKNIMALALEKENVQ-NC 220 +N PLY+GG+P L G GF GCI + + NE ++ AL + V C Sbjct: 1309 INSPLYLGGIPTSTGLSALRQGTDRPLGGFHGCIHEVRINNELQDFKALPPQSLGVSPGC 1368 Query: 221 FTCAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIG-ESCRPGLCGPGKCMNTADS 397 +C +C +G+C+ ++ + VC C PG+ G CD+ + C C GKC+ T S Sbjct: 1369 KSCT--VC-KHGLCR-SVEKDSVVCECRPGWTGPLCDQEARDPCLGHRCHHGKCVATGTS 1424 Query: 398 YKCACPVTYTGKNCEVK 448 Y C C Y G C+ K Sbjct: 1425 YMCKCAEGYGGDLCDNK 1441 Score = 58.0 bits (134), Expect = 2e-08 Identities = 27/75 (36%), Positives = 37/75 (49%), Gaps = 3/75 (4%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRP--GLC-GPGKCMNTADS 397 C N C NN C + + + YVC+C P + G CD + + C P LC KC+ Sbjct: 1036 CEDNDCENNATCVDGI--NNYVCICPPNYTGELCDEVIDHCVPELNLCQHEAKCIPLDKG 1093 Query: 398 YKCACPVTYTGKNCE 442 + C C Y+GK CE Sbjct: 1094 FSCECVPGYSGKLCE 1108 Score = 54.8 bits (126), Expect = 2e-07 Identities = 25/75 (33%), Positives = 37/75 (49%), Gaps = 3/75 (4%) Frame = +2 Query: 227 CAP--NLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLCGPG-KCMNTADS 397 C P NLC + C + G+ C C PG+ G C+ + C C G +C++T + Sbjct: 1074 CVPELNLCQHEAKCIPL--DKGFSCECVPGYSGKLCETDNDDCVAHKCRHGAQCVDTING 1131 Query: 398 YKCACPVTYTGKNCE 442 Y C CP ++G CE Sbjct: 1132 YTCTCPQGFSGPFCE 1146 Score = 52.4 bits (120), Expect = 1e-06 Identities = 26/83 (31%), Positives = 39/83 (46%), Gaps = 4/83 (4%) Frame = +2 Query: 209 VQNCFTCAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLCGPGKCMNT 388 V C C + C NNG C + E Y C C + G +C +C C G + Sbjct: 950 VAKCNACLSSPCKNNGTCTQDPVEL-YRCACPYSYKGKDCTVPINTCIQNPCQHGGTCHL 1008 Query: 389 ADSYK----CACPVTYTGKNCEV 445 +DS+K C+CP+ + G+ CE+ Sbjct: 1009 SDSHKDGFSCSCPLGFEGQRCEI 1031 Score = 42.3 bits (95), Expect = 0.001 Identities = 23/76 (30%), Positives = 38/76 (50%), Gaps = 4/76 (5%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGES---CRPGLCGPGKC-MNTAD 394 C + C ++G C T Y+C CA G+GG+ CD +S C C G+C ++ Sbjct: 1408 CLGHRC-HHGKC--VATGTSYMCKCAEGYGGDLCDNKNDSANACSAFKCHHGQCHISDQG 1464 Query: 395 SYKCACPVTYTGKNCE 442 C C ++G++C+ Sbjct: 1465 EPYCLCQPGFSGEHCQ 1480 Score = 36.3 bits (80), Expect = 0.068 Identities = 21/80 (26%), Positives = 30/80 (37%), Gaps = 8/80 (10%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESC--RPGLCGPGKCMNTADSY 400 C + C + C + + +GY C C GF G C+ + C +C N A Sbjct: 1114 CVAHKCRHGAQCVDTI--NGYTCTCPQGFSGPFCEHPPPMVLLQTSPCDQYECQNGAQCI 1171 Query: 401 ------KCACPVTYTGKNCE 442 C CP + G CE Sbjct: 1172 VVQQEPTCRCPPGFAGPRCE 1191 >U77720-1|AAC51323.1| 1214|Homo sapiens transmembrane protein Jagged protein. Length = 1214 Score = 72.1 bits (169), Expect = 1e-12 Identities = 33/72 (45%), Positives = 37/72 (51%), Gaps = 1/72 (1%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLCGPG-KCMNTADSYK 403 CA N CLN G CQ + + CLC GF GN C + C P C G +C N A Y Sbjct: 478 CASNPCLNGGHCQNEINR--FQCLCPTGFSGNLCQLDIDYCEPNPCQNGAQCYNRASDYF 535 Query: 404 CACPVTYTGKNC 439 C CP Y GKNC Sbjct: 536 CKCPEDYEGKNC 547 Score = 64.5 bits (150), Expect = 2e-10 Identities = 27/74 (36%), Positives = 39/74 (52%), Gaps = 1/74 (1%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLCGPG-KCMNTADSYK 403 C + C N G C+E T G+ C C+PG+ G C + C P C G C + + +K Sbjct: 327 CLSDPCHNRGSCKE--TSLGFECECSPGWTGPTCSTNIDDCSPNNCSHGGTCQDLVNGFK 384 Query: 404 CACPVTYTGKNCEV 445 C CP +TGK C++ Sbjct: 385 CVCPPQWTGKTCQL 398 Score = 63.3 bits (147), Expect = 5e-10 Identities = 27/78 (34%), Positives = 42/78 (53%), Gaps = 1/78 (1%) Frame = +2 Query: 212 QNCFTCAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLCGPG-KCMNT 388 QN C+P+ C N+G C + ++ Y C CAPGF G +C C+ C G C++ Sbjct: 768 QNTNDCSPHPCYNSGTCVDG--DNWYRCECAPGFAGPDCRININECQSSPCAFGATCVDE 825 Query: 389 ADSYKCACPVTYTGKNCE 442 + Y+C CP ++G C+ Sbjct: 826 INGYRCVCPPGHSGAKCQ 843 Score = 60.1 bits (139), Expect = 5e-09 Identities = 22/69 (31%), Positives = 40/69 (57%), Gaps = 1/69 (1%) Frame = +2 Query: 242 CLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLC-GPGKCMNTADSYKCACPV 418 C N+ C++ + +GY C+C PG+ G++C+R + C C G C N + ++C CP Sbjct: 445 CQNDASCRDLV--NGYRCICPPGYAGDHCERDIDECASNPCLNGGHCQNEINRFQCLCPT 502 Query: 419 TYTGKNCEV 445 ++G C++ Sbjct: 503 GFSGNLCQL 511 Score = 58.4 bits (135), Expect = 1e-08 Identities = 26/78 (33%), Positives = 38/78 (48%), Gaps = 1/78 (1%) Frame = +2 Query: 215 NCFTCAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLCGPGK-CMNTA 391 N C+PN C + G CQ+ + +G+ C+C P + G C C C K C N Sbjct: 361 NIDDCSPNNCSHGGTCQDLV--NGFKCVCPPQWTGKTCQLDANECEAKPCVNAKSCKNLI 418 Query: 392 DSYKCACPVTYTGKNCEV 445 SY C C + G+NC++ Sbjct: 419 ASYYCDCLPGWMGQNCDI 436 Score = 58.0 bits (134), Expect = 2e-08 Identities = 31/82 (37%), Positives = 43/82 (52%), Gaps = 4/82 (4%) Frame = +2 Query: 218 CFTCAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESC---RPGLCGPGKCMNT 388 C C P+ +G+C E + CLC +GG CD+ C +P L G G C NT Sbjct: 249 CDKCIPHPGCVHGICNEP-----WQCLCETNWGGQLCDKDLNYCGTHQPCLNG-GTCSNT 302 Query: 389 A-DSYKCACPVTYTGKNCEVKQ 451 D Y+C+CP Y+G NCE+ + Sbjct: 303 GPDKYQCSCPEGYSGPNCEIAE 324 Score = 54.4 bits (125), Expect = 2e-07 Identities = 23/78 (29%), Positives = 35/78 (44%), Gaps = 1/78 (1%) Frame = +2 Query: 215 NCFTCAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLCGPG-KCMNTA 391 N C+ N C N G C++ + + + C C G+ G C C C G C + Sbjct: 654 NINDCSQNPCHNGGTCRDLVND--FYCDCKNGWKGKTCHSRDSQCDEATCNNGGTCYDEG 711 Query: 392 DSYKCACPVTYTGKNCEV 445 D++KC CP + G C + Sbjct: 712 DAFKCMCPGGWEGTTCNI 729 Score = 53.6 bits (123), Expect = 4e-07 Identities = 23/81 (28%), Positives = 37/81 (45%), Gaps = 1/81 (1%) Frame = +2 Query: 206 NVQNCFTCAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLC-GPGKCM 382 N+ +C PN C N G C + + C+C G+ G C + C P C G C+ Sbjct: 728 NIARNSSCLPNPCHNGGTC--VVNGESFTCVCKEGWEGPICAQNTNDCSPHPCYNSGTCV 785 Query: 383 NTADSYKCACPVTYTGKNCEV 445 + + Y+C C + G +C + Sbjct: 786 DGDNWYRCECAPGFAGPDCRI 806 Score = 53.2 bits (122), Expect = 6e-07 Identities = 23/72 (31%), Positives = 31/72 (43%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLCGPGKCMNTADSYKC 406 C C+N C+ + Y C C PG+ G NCD C C + + Y+C Sbjct: 403 CEAKPCVNAKSCKNLIAS--YYCDCLPGWMGQNCDININDCLGQCQNDASCRDLVNGYRC 460 Query: 407 ACPVTYTGKNCE 442 CP Y G +CE Sbjct: 461 ICPPGYAGDHCE 472 Score = 50.8 bits (116), Expect = 3e-06 Identities = 25/80 (31%), Positives = 36/80 (45%), Gaps = 1/80 (1%) Frame = +2 Query: 203 ENVQNCFTCAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLC-GPGKC 379 +++ C T P CLN G C + Y C C G+ G NC+ +C C G C Sbjct: 282 KDLNYCGTHQP--CLNGGTCSNTGPDK-YQCSCPEGYSGPNCEIAEHACLSDPCHNRGSC 338 Query: 380 MNTADSYKCACPVTYTGKNC 439 T+ ++C C +TG C Sbjct: 339 KETSLGFECECSPGWTGPTC 358 Score = 48.4 bits (110), Expect = 2e-05 Identities = 22/77 (28%), Positives = 34/77 (44%), Gaps = 1/77 (1%) Frame = +2 Query: 212 QNCFTCAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLC-GPGKCMNT 388 +N C N C N G C + + + Y C+C+ G+ G C+ C C G C + Sbjct: 615 ENINDCESNPCRNGGTCIDGV--NSYKCICSDGWEGAYCETNINDCSQNPCHNGGTCRDL 672 Query: 389 ADSYKCACPVTYTGKNC 439 + + C C + GK C Sbjct: 673 VNDFYCDCKNGWKGKTC 689 Score = 43.6 bits (98), Expect = 4e-04 Identities = 22/70 (31%), Positives = 31/70 (44%), Gaps = 1/70 (1%) Frame = +2 Query: 236 NLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLC-GPGKCMNTADSYKCAC 412 N+C +G C+ + + C C GF G C C C G C++ +SYKC C Sbjct: 584 NVCGPHGKCKSQ-SGGKFTCDCNKGFTGTYCHENINDCESNPCRNGGTCIDGVNSYKCIC 642 Query: 413 PVTYTGKNCE 442 + G CE Sbjct: 643 SDGWEGAYCE 652 Score = 37.9 bits (84), Expect = 0.022 Identities = 15/46 (32%), Positives = 20/46 (43%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLC 364 C PN C N C ++ Y C C + G NC + + CR C Sbjct: 516 CEPNPCQNGAQCYNRASD--YFCKCPEDYEGKNCSHLKDHCRTTPC 559 Score = 31.5 bits (68), Expect = 1.9 Identities = 14/46 (30%), Positives = 20/46 (43%), Gaps = 1/46 (2%) Frame = +2 Query: 215 NCFTCAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRI-GESC 349 N C + C C + + +GY C+C PG G C + G C Sbjct: 807 NINECQSSPCAFGATCVDEI--NGYRCVCPPGHSGAKCQEVSGRPC 850 >U73936-1|AAC52020.1| 1218|Homo sapiens Jagged 1 protein. Length = 1218 Score = 72.1 bits (169), Expect = 1e-12 Identities = 33/72 (45%), Positives = 37/72 (51%), Gaps = 1/72 (1%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLCGPG-KCMNTADSYK 403 CA N CLN G CQ + + CLC GF GN C + C P C G +C N A Y Sbjct: 491 CASNPCLNGGHCQNEINR--FQCLCPTGFSGNLCQLDIDYCEPNPCQNGAQCYNRASDYF 548 Query: 404 CACPVTYTGKNC 439 C CP Y GKNC Sbjct: 549 CKCPEDYEGKNC 560 Score = 64.5 bits (150), Expect = 2e-10 Identities = 27/74 (36%), Positives = 39/74 (52%), Gaps = 1/74 (1%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLCGPG-KCMNTADSYK 403 C + C N G C+E T G+ C C+PG+ G C + C P C G C + + +K Sbjct: 340 CLSDPCHNRGSCKE--TSLGFECECSPGWTGPTCSTNIDDCSPNNCSHGGTCQDLVNGFK 397 Query: 404 CACPVTYTGKNCEV 445 C CP +TGK C++ Sbjct: 398 CVCPPQWTGKTCQL 411 Score = 63.3 bits (147), Expect = 5e-10 Identities = 27/78 (34%), Positives = 42/78 (53%), Gaps = 1/78 (1%) Frame = +2 Query: 212 QNCFTCAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLCGPG-KCMNT 388 QN C+P+ C N+G C + ++ Y C CAPGF G +C C+ C G C++ Sbjct: 781 QNTNDCSPHPCYNSGTCVDG--DNWYRCECAPGFAGPDCRININECQSSPCAFGATCVDE 838 Query: 389 ADSYKCACPVTYTGKNCE 442 + Y+C CP ++G C+ Sbjct: 839 INGYRCVCPPGHSGAKCQ 856 Score = 60.1 bits (139), Expect = 5e-09 Identities = 22/69 (31%), Positives = 40/69 (57%), Gaps = 1/69 (1%) Frame = +2 Query: 242 CLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLC-GPGKCMNTADSYKCACPV 418 C N+ C++ + +GY C+C PG+ G++C+R + C C G C N + ++C CP Sbjct: 458 CQNDASCRDLV--NGYRCICPPGYAGDHCERDIDECASNPCLNGGHCQNEINRFQCLCPT 515 Query: 419 TYTGKNCEV 445 ++G C++ Sbjct: 516 GFSGNLCQL 524 Score = 58.4 bits (135), Expect = 1e-08 Identities = 26/78 (33%), Positives = 38/78 (48%), Gaps = 1/78 (1%) Frame = +2 Query: 215 NCFTCAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLCGPGK-CMNTA 391 N C+PN C + G CQ+ + +G+ C+C P + G C C C K C N Sbjct: 374 NIDDCSPNNCSHGGTCQDLV--NGFKCVCPPQWTGKTCQLDANECEAKPCVNAKSCKNLI 431 Query: 392 DSYKCACPVTYTGKNCEV 445 SY C C + G+NC++ Sbjct: 432 ASYYCDCLPGWMGQNCDI 449 Score = 58.0 bits (134), Expect = 2e-08 Identities = 31/82 (37%), Positives = 43/82 (52%), Gaps = 4/82 (4%) Frame = +2 Query: 218 CFTCAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESC---RPGLCGPGKCMNT 388 C C P+ +G+C E + CLC +GG CD+ C +P L G G C NT Sbjct: 262 CDKCIPHPGCVHGICNEP-----WQCLCETNWGGQLCDKDLNYCGTHQPCLNG-GTCSNT 315 Query: 389 A-DSYKCACPVTYTGKNCEVKQ 451 D Y+C+CP Y+G NCE+ + Sbjct: 316 GPDKYQCSCPEGYSGPNCEIAE 337 Score = 54.4 bits (125), Expect = 2e-07 Identities = 23/78 (29%), Positives = 35/78 (44%), Gaps = 1/78 (1%) Frame = +2 Query: 215 NCFTCAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLCGPG-KCMNTA 391 N C+ N C N G C++ + + + C C G+ G C C C G C + Sbjct: 667 NINDCSQNPCHNGGTCRDLVND--FYCDCKNGWKGKTCHSRDSQCDEATCNNGGTCYDEG 724 Query: 392 DSYKCACPVTYTGKNCEV 445 D++KC CP + G C + Sbjct: 725 DAFKCMCPGGWEGTTCNI 742 Score = 53.6 bits (123), Expect = 4e-07 Identities = 23/81 (28%), Positives = 37/81 (45%), Gaps = 1/81 (1%) Frame = +2 Query: 206 NVQNCFTCAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLC-GPGKCM 382 N+ +C PN C N G C + + C+C G+ G C + C P C G C+ Sbjct: 741 NIARNSSCLPNPCHNGGTC--VVNGESFTCVCKEGWEGPICAQNTNDCSPHPCYNSGTCV 798 Query: 383 NTADSYKCACPVTYTGKNCEV 445 + + Y+C C + G +C + Sbjct: 799 DGDNWYRCECAPGFAGPDCRI 819 Score = 53.2 bits (122), Expect = 6e-07 Identities = 23/72 (31%), Positives = 31/72 (43%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLCGPGKCMNTADSYKC 406 C C+N C+ + Y C C PG+ G NCD C C + + Y+C Sbjct: 416 CEAKPCVNAKSCKNLIAS--YYCDCLPGWMGQNCDININDCLGQCQNDASCRDLVNGYRC 473 Query: 407 ACPVTYTGKNCE 442 CP Y G +CE Sbjct: 474 ICPPGYAGDHCE 485 Score = 50.8 bits (116), Expect = 3e-06 Identities = 25/80 (31%), Positives = 36/80 (45%), Gaps = 1/80 (1%) Frame = +2 Query: 203 ENVQNCFTCAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLC-GPGKC 379 +++ C T P CLN G C + Y C C G+ G NC+ +C C G C Sbjct: 295 KDLNYCGTHQP--CLNGGTCSNTGPDK-YQCSCPEGYSGPNCEIAEHACLSDPCHNRGSC 351 Query: 380 MNTADSYKCACPVTYTGKNC 439 T+ ++C C +TG C Sbjct: 352 KETSLGFECECSPGWTGPTC 371 Score = 48.4 bits (110), Expect = 2e-05 Identities = 22/77 (28%), Positives = 34/77 (44%), Gaps = 1/77 (1%) Frame = +2 Query: 212 QNCFTCAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLC-GPGKCMNT 388 +N C N C N G C + + + Y C+C+ G+ G C+ C C G C + Sbjct: 628 ENINDCESNPCRNGGTCIDGV--NSYKCICSDGWEGAYCETNINDCSQNPCHNGGTCRDL 685 Query: 389 ADSYKCACPVTYTGKNC 439 + + C C + GK C Sbjct: 686 VNDFYCDCKNGWKGKTC 702 Score = 43.6 bits (98), Expect = 4e-04 Identities = 22/70 (31%), Positives = 31/70 (44%), Gaps = 1/70 (1%) Frame = +2 Query: 236 NLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLC-GPGKCMNTADSYKCAC 412 N+C +G C+ + + C C GF G C C C G C++ +SYKC C Sbjct: 597 NVCGPHGKCKSQ-SGGKFTCDCNKGFTGTYCHENINDCESNPCRNGGTCIDGVNSYKCIC 655 Query: 413 PVTYTGKNCE 442 + G CE Sbjct: 656 SDGWEGAYCE 665 Score = 37.9 bits (84), Expect = 0.022 Identities = 15/46 (32%), Positives = 20/46 (43%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLC 364 C PN C N C ++ Y C C + G NC + + CR C Sbjct: 529 CEPNPCQNGAQCYNRASD--YFCKCPEDYEGKNCSHLKDHCRTTPC 572 Score = 31.5 bits (68), Expect = 1.9 Identities = 14/46 (30%), Positives = 20/46 (43%), Gaps = 1/46 (2%) Frame = +2 Query: 215 NCFTCAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRI-GESC 349 N C + C C + + +GY C+C PG G C + G C Sbjct: 820 NINECQSSPCAFGATCVDEI--NGYRCVCPPGHSGAKCQEVSGRPC 863 >U61276-1|AAB39007.1| 1218|Homo sapiens transmembrane protein Jagged 1 protein. Length = 1218 Score = 72.1 bits (169), Expect = 1e-12 Identities = 33/72 (45%), Positives = 37/72 (51%), Gaps = 1/72 (1%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLCGPG-KCMNTADSYK 403 CA N CLN G CQ + + CLC GF GN C + C P C G +C N A Y Sbjct: 491 CASNPCLNGGHCQNEINR--FQCLCPTGFSGNLCQLDIDYCEPNPCQNGAQCYNRASDYF 548 Query: 404 CACPVTYTGKNC 439 C CP Y GKNC Sbjct: 549 CKCPEDYEGKNC 560 Score = 64.5 bits (150), Expect = 2e-10 Identities = 27/74 (36%), Positives = 39/74 (52%), Gaps = 1/74 (1%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLCGPG-KCMNTADSYK 403 C + C N G C+E T G+ C C+PG+ G C + C P C G C + + +K Sbjct: 340 CLSDPCHNRGSCKE--TSLGFECECSPGWTGPTCSTNIDDCSPNNCSHGGTCQDLVNGFK 397 Query: 404 CACPVTYTGKNCEV 445 C CP +TGK C++ Sbjct: 398 CVCPPQWTGKTCQL 411 Score = 63.3 bits (147), Expect = 5e-10 Identities = 27/78 (34%), Positives = 42/78 (53%), Gaps = 1/78 (1%) Frame = +2 Query: 212 QNCFTCAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLCGPG-KCMNT 388 QN C+P+ C N+G C + ++ Y C CAPGF G +C C+ C G C++ Sbjct: 781 QNTNDCSPHPCYNSGTCVDG--DNWYRCECAPGFAGPDCRININECQSSPCAFGATCVDE 838 Query: 389 ADSYKCACPVTYTGKNCE 442 + Y+C CP ++G C+ Sbjct: 839 INGYRCVCPPGHSGAKCQ 856 Score = 60.1 bits (139), Expect = 5e-09 Identities = 22/69 (31%), Positives = 40/69 (57%), Gaps = 1/69 (1%) Frame = +2 Query: 242 CLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLC-GPGKCMNTADSYKCACPV 418 C N+ C++ + +GY C+C PG+ G++C+R + C C G C N + ++C CP Sbjct: 458 CQNDASCRDLV--NGYRCICPPGYAGDHCERDIDECASNPCLNGGHCQNEINRFQCLCPT 515 Query: 419 TYTGKNCEV 445 ++G C++ Sbjct: 516 GFSGNLCQL 524 Score = 58.4 bits (135), Expect = 1e-08 Identities = 26/78 (33%), Positives = 38/78 (48%), Gaps = 1/78 (1%) Frame = +2 Query: 215 NCFTCAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLCGPGK-CMNTA 391 N C+PN C + G CQ+ + +G+ C+C P + G C C C K C N Sbjct: 374 NIDDCSPNNCSHGGTCQDLV--NGFKCVCPPQWTGKTCQLDANECEAKPCVNAKSCKNLI 431 Query: 392 DSYKCACPVTYTGKNCEV 445 SY C C + G+NC++ Sbjct: 432 ASYYCDCLPGWMGQNCDI 449 Score = 58.0 bits (134), Expect = 2e-08 Identities = 31/82 (37%), Positives = 43/82 (52%), Gaps = 4/82 (4%) Frame = +2 Query: 218 CFTCAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESC---RPGLCGPGKCMNT 388 C C P+ +G+C E + CLC +GG CD+ C +P L G G C NT Sbjct: 262 CDKCIPHPGCVHGICNEP-----WQCLCETNWGGQLCDKDLNYCGTHQPCLNG-GTCSNT 315 Query: 389 A-DSYKCACPVTYTGKNCEVKQ 451 D Y+C+CP Y+G NCE+ + Sbjct: 316 GPDKYQCSCPEGYSGPNCEIAE 337 Score = 54.4 bits (125), Expect = 2e-07 Identities = 23/78 (29%), Positives = 35/78 (44%), Gaps = 1/78 (1%) Frame = +2 Query: 215 NCFTCAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLCGPG-KCMNTA 391 N C+ N C N G C++ + + + C C G+ G C C C G C + Sbjct: 667 NINDCSQNPCHNGGTCRDLVND--FYCDCKNGWKGKTCHSRDSQCDEATCNNGGTCYDEG 724 Query: 392 DSYKCACPVTYTGKNCEV 445 D++KC CP + G C + Sbjct: 725 DAFKCMCPGGWEGTTCNI 742 Score = 53.6 bits (123), Expect = 4e-07 Identities = 23/81 (28%), Positives = 37/81 (45%), Gaps = 1/81 (1%) Frame = +2 Query: 206 NVQNCFTCAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLC-GPGKCM 382 N+ +C PN C N G C + + C+C G+ G C + C P C G C+ Sbjct: 741 NIARNSSCLPNPCHNGGTC--VVNGESFTCVCKEGWEGPICAQNTNDCSPHPCYNSGTCV 798 Query: 383 NTADSYKCACPVTYTGKNCEV 445 + + Y+C C + G +C + Sbjct: 799 DGDNWYRCECAPGFAGPDCRI 819 Score = 53.2 bits (122), Expect = 6e-07 Identities = 23/72 (31%), Positives = 31/72 (43%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLCGPGKCMNTADSYKC 406 C C+N C+ + Y C C PG+ G NCD C C + + Y+C Sbjct: 416 CEAKPCVNAKSCKNLIAS--YYCDCLPGWMGQNCDININDCLGQCQNDASCRDLVNGYRC 473 Query: 407 ACPVTYTGKNCE 442 CP Y G +CE Sbjct: 474 ICPPGYAGDHCE 485 Score = 50.8 bits (116), Expect = 3e-06 Identities = 25/80 (31%), Positives = 36/80 (45%), Gaps = 1/80 (1%) Frame = +2 Query: 203 ENVQNCFTCAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLC-GPGKC 379 +++ C T P CLN G C + Y C C G+ G NC+ +C C G C Sbjct: 295 KDLNYCGTHQP--CLNGGTCSNTGPDK-YQCSCPEGYSGPNCEIAEHACLSDPCHNRGSC 351 Query: 380 MNTADSYKCACPVTYTGKNC 439 T+ ++C C +TG C Sbjct: 352 KETSLGFECECSPGWTGPTC 371 Score = 48.4 bits (110), Expect = 2e-05 Identities = 22/77 (28%), Positives = 34/77 (44%), Gaps = 1/77 (1%) Frame = +2 Query: 212 QNCFTCAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLC-GPGKCMNT 388 +N C N C N G C + + + Y C+C+ G+ G C+ C C G C + Sbjct: 628 ENINDCESNPCRNGGTCIDGV--NSYKCICSDGWEGAYCETNINDCSQNPCHNGGTCRDL 685 Query: 389 ADSYKCACPVTYTGKNC 439 + + C C + GK C Sbjct: 686 VNDFYCDCKNGWKGKTC 702 Score = 43.6 bits (98), Expect = 4e-04 Identities = 22/70 (31%), Positives = 31/70 (44%), Gaps = 1/70 (1%) Frame = +2 Query: 236 NLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLC-GPGKCMNTADSYKCAC 412 N+C +G C+ + + C C GF G C C C G C++ +SYKC C Sbjct: 597 NVCGPHGKCKSQ-SGGKFTCDCNKGFTGTYCHENINDCESNPCRNGGTCIDGVNSYKCIC 655 Query: 413 PVTYTGKNCE 442 + G CE Sbjct: 656 SDGWEGAYCE 665 Score = 37.9 bits (84), Expect = 0.022 Identities = 15/46 (32%), Positives = 20/46 (43%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLC 364 C PN C N C ++ Y C C + G NC + + CR C Sbjct: 529 CEPNPCQNGAQCYNRASD--YFCKCPEDYEGKNCSHLKDHCRTTPC 572 Score = 31.5 bits (68), Expect = 1.9 Identities = 14/46 (30%), Positives = 20/46 (43%), Gaps = 1/46 (2%) Frame = +2 Query: 215 NCFTCAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRI-GESC 349 N C + C C + + +GY C+C PG G C + G C Sbjct: 820 NINECQSSPCAFGATCVDEI--NGYRCVCPPGHSGAKCQEVSGRPC 863 >BC126207-1|AAI26208.1| 1218|Homo sapiens jagged 1 (Alagille syndrome) protein. Length = 1218 Score = 72.1 bits (169), Expect = 1e-12 Identities = 33/72 (45%), Positives = 37/72 (51%), Gaps = 1/72 (1%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLCGPG-KCMNTADSYK 403 CA N CLN G CQ + + CLC GF GN C + C P C G +C N A Y Sbjct: 491 CASNPCLNGGHCQNEINR--FQCLCPTGFSGNLCQLDIDYCEPNPCQNGAQCYNRASDYF 548 Query: 404 CACPVTYTGKNC 439 C CP Y GKNC Sbjct: 549 CKCPEDYEGKNC 560 Score = 64.5 bits (150), Expect = 2e-10 Identities = 27/74 (36%), Positives = 39/74 (52%), Gaps = 1/74 (1%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLCGPG-KCMNTADSYK 403 C + C N G C+E T G+ C C+PG+ G C + C P C G C + + +K Sbjct: 340 CLSDPCHNRGSCKE--TSLGFECECSPGWTGPTCSTNIDDCSPNNCSHGGTCQDLVNGFK 397 Query: 404 CACPVTYTGKNCEV 445 C CP +TGK C++ Sbjct: 398 CVCPPQWTGKTCQL 411 Score = 63.3 bits (147), Expect = 5e-10 Identities = 27/78 (34%), Positives = 42/78 (53%), Gaps = 1/78 (1%) Frame = +2 Query: 212 QNCFTCAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLCGPG-KCMNT 388 QN C+P+ C N+G C + ++ Y C CAPGF G +C C+ C G C++ Sbjct: 781 QNTNDCSPHPCYNSGTCVDG--DNWYRCECAPGFAGPDCRININECQSSPCAFGATCVDE 838 Query: 389 ADSYKCACPVTYTGKNCE 442 + Y+C CP ++G C+ Sbjct: 839 INGYRCVCPPGHSGAKCQ 856 Score = 60.1 bits (139), Expect = 5e-09 Identities = 22/69 (31%), Positives = 40/69 (57%), Gaps = 1/69 (1%) Frame = +2 Query: 242 CLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLC-GPGKCMNTADSYKCACPV 418 C N+ C++ + +GY C+C PG+ G++C+R + C C G C N + ++C CP Sbjct: 458 CQNDASCRDLV--NGYRCICPPGYAGDHCERDIDECASNPCLNGGHCQNEINRFQCLCPT 515 Query: 419 TYTGKNCEV 445 ++G C++ Sbjct: 516 GFSGNLCQL 524 Score = 58.4 bits (135), Expect = 1e-08 Identities = 26/78 (33%), Positives = 38/78 (48%), Gaps = 1/78 (1%) Frame = +2 Query: 215 NCFTCAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLCGPGK-CMNTA 391 N C+PN C + G CQ+ + +G+ C+C P + G C C C K C N Sbjct: 374 NIDDCSPNNCSHGGTCQDLV--NGFKCVCPPQWTGKTCQLDANECEAKPCVNAKSCKNLI 431 Query: 392 DSYKCACPVTYTGKNCEV 445 SY C C + G+NC++ Sbjct: 432 ASYYCDCLPGWMGQNCDI 449 Score = 58.0 bits (134), Expect = 2e-08 Identities = 31/82 (37%), Positives = 43/82 (52%), Gaps = 4/82 (4%) Frame = +2 Query: 218 CFTCAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESC---RPGLCGPGKCMNT 388 C C P+ +G+C E + CLC +GG CD+ C +P L G G C NT Sbjct: 262 CDKCIPHPGCVHGICNEP-----WQCLCETNWGGQLCDKDLNYCGTHQPCLNG-GTCSNT 315 Query: 389 A-DSYKCACPVTYTGKNCEVKQ 451 D Y+C+CP Y+G NCE+ + Sbjct: 316 GPDKYQCSCPEGYSGPNCEIAE 337 Score = 54.4 bits (125), Expect = 2e-07 Identities = 23/78 (29%), Positives = 35/78 (44%), Gaps = 1/78 (1%) Frame = +2 Query: 215 NCFTCAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLCGPG-KCMNTA 391 N C+ N C N G C++ + + + C C G+ G C C C G C + Sbjct: 667 NINDCSQNPCHNGGTCRDLVND--FYCDCKNGWKGKTCHSRDSQCDEATCNNGGTCYDEG 724 Query: 392 DSYKCACPVTYTGKNCEV 445 D++KC CP + G C + Sbjct: 725 DAFKCMCPGGWEGTTCNI 742 Score = 53.6 bits (123), Expect = 4e-07 Identities = 23/81 (28%), Positives = 37/81 (45%), Gaps = 1/81 (1%) Frame = +2 Query: 206 NVQNCFTCAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLC-GPGKCM 382 N+ +C PN C N G C + + C+C G+ G C + C P C G C+ Sbjct: 741 NIARNSSCLPNPCHNGGTC--VVNGESFTCVCKEGWEGPICAQNTNDCSPHPCYNSGTCV 798 Query: 383 NTADSYKCACPVTYTGKNCEV 445 + + Y+C C + G +C + Sbjct: 799 DGDNWYRCECAPGFAGPDCRI 819 Score = 53.2 bits (122), Expect = 6e-07 Identities = 23/72 (31%), Positives = 31/72 (43%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLCGPGKCMNTADSYKC 406 C C+N C+ + Y C C PG+ G NCD C C + + Y+C Sbjct: 416 CEAKPCVNAKSCKNLIAS--YYCDCLPGWMGQNCDININDCLGQCQNDASCRDLVNGYRC 473 Query: 407 ACPVTYTGKNCE 442 CP Y G +CE Sbjct: 474 ICPPGYAGDHCE 485 Score = 50.8 bits (116), Expect = 3e-06 Identities = 25/80 (31%), Positives = 36/80 (45%), Gaps = 1/80 (1%) Frame = +2 Query: 203 ENVQNCFTCAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLC-GPGKC 379 +++ C T P CLN G C + Y C C G+ G NC+ +C C G C Sbjct: 295 KDLNYCGTHQP--CLNGGTCSNTGPDK-YQCSCPEGYSGPNCEIAEHACLSDPCHNRGSC 351 Query: 380 MNTADSYKCACPVTYTGKNC 439 T+ ++C C +TG C Sbjct: 352 KETSLGFECECSPGWTGPTC 371 Score = 48.4 bits (110), Expect = 2e-05 Identities = 22/77 (28%), Positives = 34/77 (44%), Gaps = 1/77 (1%) Frame = +2 Query: 212 QNCFTCAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLC-GPGKCMNT 388 +N C N C N G C + + + Y C+C+ G+ G C+ C C G C + Sbjct: 628 ENINDCESNPCRNGGTCIDGV--NSYKCICSDGWEGAYCETNINDCSQNPCHNGGTCRDL 685 Query: 389 ADSYKCACPVTYTGKNC 439 + + C C + GK C Sbjct: 686 VNDFYCDCKNGWKGKTC 702 Score = 43.6 bits (98), Expect = 4e-04 Identities = 22/70 (31%), Positives = 31/70 (44%), Gaps = 1/70 (1%) Frame = +2 Query: 236 NLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLC-GPGKCMNTADSYKCAC 412 N+C +G C+ + + C C GF G C C C G C++ +SYKC C Sbjct: 597 NVCGPHGKCKSQ-SGGKFTCDCNKGFTGTYCHENINDCESNPCRNGGTCIDGVNSYKCIC 655 Query: 413 PVTYTGKNCE 442 + G CE Sbjct: 656 SDGWEGAYCE 665 Score = 37.9 bits (84), Expect = 0.022 Identities = 15/46 (32%), Positives = 20/46 (43%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLC 364 C PN C N C ++ Y C C + G NC + + CR C Sbjct: 529 CEPNPCQNGAQCYNRASD--YFCKCPEDYEGKNCSHLKDHCRTTPC 572 Score = 31.5 bits (68), Expect = 1.9 Identities = 14/46 (30%), Positives = 20/46 (43%), Gaps = 1/46 (2%) Frame = +2 Query: 215 NCFTCAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRI-GESC 349 N C + C C + + +GY C+C PG G C + G C Sbjct: 820 NINECQSSPCAFGATCVDEI--NGYRCVCPPGHSGAKCQEVSGRPC 863 >BC126205-1|AAI26206.1| 1218|Homo sapiens jagged 1 (Alagille syndrome) protein. Length = 1218 Score = 72.1 bits (169), Expect = 1e-12 Identities = 33/72 (45%), Positives = 37/72 (51%), Gaps = 1/72 (1%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLCGPG-KCMNTADSYK 403 CA N CLN G CQ + + CLC GF GN C + C P C G +C N A Y Sbjct: 491 CASNPCLNGGHCQNEINR--FQCLCPTGFSGNLCQLDIDYCEPNPCQNGAQCYNRASDYF 548 Query: 404 CACPVTYTGKNC 439 C CP Y GKNC Sbjct: 549 CKCPEDYEGKNC 560 Score = 64.5 bits (150), Expect = 2e-10 Identities = 27/74 (36%), Positives = 39/74 (52%), Gaps = 1/74 (1%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLCGPG-KCMNTADSYK 403 C + C N G C+E T G+ C C+PG+ G C + C P C G C + + +K Sbjct: 340 CLSDPCHNRGSCKE--TSLGFECECSPGWTGPTCSTNIDDCSPNNCSHGGTCQDLVNGFK 397 Query: 404 CACPVTYTGKNCEV 445 C CP +TGK C++ Sbjct: 398 CVCPPQWTGKTCQL 411 Score = 63.3 bits (147), Expect = 5e-10 Identities = 27/78 (34%), Positives = 42/78 (53%), Gaps = 1/78 (1%) Frame = +2 Query: 212 QNCFTCAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLCGPG-KCMNT 388 QN C+P+ C N+G C + ++ Y C CAPGF G +C C+ C G C++ Sbjct: 781 QNTNDCSPHPCYNSGTCVDG--DNWYRCECAPGFAGPDCRININECQSSPCAFGATCVDE 838 Query: 389 ADSYKCACPVTYTGKNCE 442 + Y+C CP ++G C+ Sbjct: 839 INGYRCVCPPGHSGAKCQ 856 Score = 60.1 bits (139), Expect = 5e-09 Identities = 22/69 (31%), Positives = 40/69 (57%), Gaps = 1/69 (1%) Frame = +2 Query: 242 CLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLC-GPGKCMNTADSYKCACPV 418 C N+ C++ + +GY C+C PG+ G++C+R + C C G C N + ++C CP Sbjct: 458 CQNDASCRDLV--NGYRCICPPGYAGDHCERDIDECASNPCLNGGHCQNEINRFQCLCPT 515 Query: 419 TYTGKNCEV 445 ++G C++ Sbjct: 516 GFSGNLCQL 524 Score = 58.4 bits (135), Expect = 1e-08 Identities = 26/78 (33%), Positives = 38/78 (48%), Gaps = 1/78 (1%) Frame = +2 Query: 215 NCFTCAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLCGPGK-CMNTA 391 N C+PN C + G CQ+ + +G+ C+C P + G C C C K C N Sbjct: 374 NIDDCSPNNCSHGGTCQDLV--NGFKCVCPPQWTGKTCQLDANECEAKPCVNAKSCKNLI 431 Query: 392 DSYKCACPVTYTGKNCEV 445 SY C C + G+NC++ Sbjct: 432 ASYYCDCLPGWMGQNCDI 449 Score = 58.0 bits (134), Expect = 2e-08 Identities = 31/82 (37%), Positives = 43/82 (52%), Gaps = 4/82 (4%) Frame = +2 Query: 218 CFTCAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESC---RPGLCGPGKCMNT 388 C C P+ +G+C E + CLC +GG CD+ C +P L G G C NT Sbjct: 262 CDKCIPHPGCVHGICNEP-----WQCLCETNWGGQLCDKDLNYCGTHQPCLNG-GTCSNT 315 Query: 389 A-DSYKCACPVTYTGKNCEVKQ 451 D Y+C+CP Y+G NCE+ + Sbjct: 316 GPDKYQCSCPEGYSGPNCEIAE 337 Score = 54.4 bits (125), Expect = 2e-07 Identities = 23/78 (29%), Positives = 35/78 (44%), Gaps = 1/78 (1%) Frame = +2 Query: 215 NCFTCAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLCGPG-KCMNTA 391 N C+ N C N G C++ + + + C C G+ G C C C G C + Sbjct: 667 NINDCSQNPCHNGGTCRDLVND--FYCDCKNGWKGKTCHSRDSQCDEATCNNGGTCYDEG 724 Query: 392 DSYKCACPVTYTGKNCEV 445 D++KC CP + G C + Sbjct: 725 DAFKCMCPGGWEGTTCNI 742 Score = 53.6 bits (123), Expect = 4e-07 Identities = 23/81 (28%), Positives = 37/81 (45%), Gaps = 1/81 (1%) Frame = +2 Query: 206 NVQNCFTCAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLC-GPGKCM 382 N+ +C PN C N G C + + C+C G+ G C + C P C G C+ Sbjct: 741 NIARNSSCLPNPCHNGGTC--VVNGESFTCVCKEGWEGPICAQNTNDCSPHPCYNSGTCV 798 Query: 383 NTADSYKCACPVTYTGKNCEV 445 + + Y+C C + G +C + Sbjct: 799 DGDNWYRCECAPGFAGPDCRI 819 Score = 53.2 bits (122), Expect = 6e-07 Identities = 23/72 (31%), Positives = 31/72 (43%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLCGPGKCMNTADSYKC 406 C C+N C+ + Y C C PG+ G NCD C C + + Y+C Sbjct: 416 CEAKPCVNAKSCKNLIAS--YYCDCLPGWMGQNCDININDCLGQCQNDASCRDLVNGYRC 473 Query: 407 ACPVTYTGKNCE 442 CP Y G +CE Sbjct: 474 ICPPGYAGDHCE 485 Score = 50.8 bits (116), Expect = 3e-06 Identities = 25/80 (31%), Positives = 36/80 (45%), Gaps = 1/80 (1%) Frame = +2 Query: 203 ENVQNCFTCAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLC-GPGKC 379 +++ C T P CLN G C + Y C C G+ G NC+ +C C G C Sbjct: 295 KDLNYCGTHQP--CLNGGTCSNTGPDK-YQCSCPEGYSGPNCEIAEHACLSDPCHNRGSC 351 Query: 380 MNTADSYKCACPVTYTGKNC 439 T+ ++C C +TG C Sbjct: 352 KETSLGFECECSPGWTGPTC 371 Score = 48.4 bits (110), Expect = 2e-05 Identities = 22/77 (28%), Positives = 34/77 (44%), Gaps = 1/77 (1%) Frame = +2 Query: 212 QNCFTCAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLC-GPGKCMNT 388 +N C N C N G C + + + Y C+C+ G+ G C+ C C G C + Sbjct: 628 ENINDCESNPCRNGGTCIDGV--NSYKCICSDGWEGAYCETNINDCSQNPCHNGGTCRDL 685 Query: 389 ADSYKCACPVTYTGKNC 439 + + C C + GK C Sbjct: 686 VNDFYCDCKNGWKGKTC 702 Score = 43.6 bits (98), Expect = 4e-04 Identities = 22/70 (31%), Positives = 31/70 (44%), Gaps = 1/70 (1%) Frame = +2 Query: 236 NLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLC-GPGKCMNTADSYKCAC 412 N+C +G C+ + + C C GF G C C C G C++ +SYKC C Sbjct: 597 NVCGPHGKCKSQ-SGGKFTCDCNKGFTGTYCHENINDCESNPCRNGGTCIDGVNSYKCIC 655 Query: 413 PVTYTGKNCE 442 + G CE Sbjct: 656 SDGWEGAYCE 665 Score = 37.9 bits (84), Expect = 0.022 Identities = 15/46 (32%), Positives = 20/46 (43%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLC 364 C PN C N C ++ Y C C + G NC + + CR C Sbjct: 529 CEPNPCQNGAQCYNRASD--YFCKCPEDYEGKNCSHLKDHCRTTPC 572 Score = 31.5 bits (68), Expect = 1.9 Identities = 14/46 (30%), Positives = 20/46 (43%), Gaps = 1/46 (2%) Frame = +2 Query: 215 NCFTCAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRI-GESC 349 N C + C C + + +GY C+C PG G C + G C Sbjct: 820 NINECQSSPCAFGATCVDEI--NGYRCVCPPGHSGAKCQEVSGRPC 863 >BC098393-1|AAH98393.1| 1218|Homo sapiens jagged 1 (Alagille syndrome) protein. Length = 1218 Score = 72.1 bits (169), Expect = 1e-12 Identities = 33/72 (45%), Positives = 37/72 (51%), Gaps = 1/72 (1%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLCGPG-KCMNTADSYK 403 CA N CLN G CQ + + CLC GF GN C + C P C G +C N A Y Sbjct: 491 CASNPCLNGGHCQNEINR--FQCLCPTGFSGNLCQLDIDYCEPNPCQNGAQCYNRASDYF 548 Query: 404 CACPVTYTGKNC 439 C CP Y GKNC Sbjct: 549 CKCPEDYEGKNC 560 Score = 64.5 bits (150), Expect = 2e-10 Identities = 27/74 (36%), Positives = 39/74 (52%), Gaps = 1/74 (1%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLCGPG-KCMNTADSYK 403 C + C N G C+E T G+ C C+PG+ G C + C P C G C + + +K Sbjct: 340 CLSDPCHNRGSCKE--TSLGFECECSPGWTGPTCSTNIDDCSPNNCSHGGTCQDLVNGFK 397 Query: 404 CACPVTYTGKNCEV 445 C CP +TGK C++ Sbjct: 398 CVCPPQWTGKTCQL 411 Score = 63.3 bits (147), Expect = 5e-10 Identities = 27/78 (34%), Positives = 42/78 (53%), Gaps = 1/78 (1%) Frame = +2 Query: 212 QNCFTCAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLCGPG-KCMNT 388 QN C+P+ C N+G C + ++ Y C CAPGF G +C C+ C G C++ Sbjct: 781 QNTNDCSPHPCYNSGTCVDG--DNWYRCECAPGFAGPDCRININECQSSPCAFGATCVDE 838 Query: 389 ADSYKCACPVTYTGKNCE 442 + Y+C CP ++G C+ Sbjct: 839 INGYRCVCPPGHSGAKCQ 856 Score = 60.1 bits (139), Expect = 5e-09 Identities = 22/69 (31%), Positives = 40/69 (57%), Gaps = 1/69 (1%) Frame = +2 Query: 242 CLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLC-GPGKCMNTADSYKCACPV 418 C N+ C++ + +GY C+C PG+ G++C+R + C C G C N + ++C CP Sbjct: 458 CQNDASCRDLV--NGYRCICPPGYAGDHCERDIDECASNPCLNGGHCQNEINRFQCLCPT 515 Query: 419 TYTGKNCEV 445 ++G C++ Sbjct: 516 GFSGNLCQL 524 Score = 58.4 bits (135), Expect = 1e-08 Identities = 26/78 (33%), Positives = 38/78 (48%), Gaps = 1/78 (1%) Frame = +2 Query: 215 NCFTCAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLCGPGK-CMNTA 391 N C+PN C + G CQ+ + +G+ C+C P + G C C C K C N Sbjct: 374 NIDDCSPNNCSHGGTCQDLV--NGFKCVCPPQWTGKTCQLDANECEAKPCVNAKSCKNLI 431 Query: 392 DSYKCACPVTYTGKNCEV 445 SY C C + G+NC++ Sbjct: 432 ASYYCDCLPGWMGQNCDI 449 Score = 58.0 bits (134), Expect = 2e-08 Identities = 31/82 (37%), Positives = 43/82 (52%), Gaps = 4/82 (4%) Frame = +2 Query: 218 CFTCAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESC---RPGLCGPGKCMNT 388 C C P+ +G+C E + CLC +GG CD+ C +P L G G C NT Sbjct: 262 CDKCIPHPGCVHGICNEP-----WQCLCETNWGGQLCDKDLNYCGTHQPCLNG-GTCSNT 315 Query: 389 A-DSYKCACPVTYTGKNCEVKQ 451 D Y+C+CP Y+G NCE+ + Sbjct: 316 GPDKYQCSCPEGYSGPNCEIAE 337 Score = 54.4 bits (125), Expect = 2e-07 Identities = 23/78 (29%), Positives = 35/78 (44%), Gaps = 1/78 (1%) Frame = +2 Query: 215 NCFTCAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLCGPG-KCMNTA 391 N C+ N C N G C++ + + + C C G+ G C C C G C + Sbjct: 667 NINDCSQNPCHNGGTCRDLVND--FYCDCKNGWKGKTCHSRDSQCDEATCNNGGTCYDEG 724 Query: 392 DSYKCACPVTYTGKNCEV 445 D++KC CP + G C + Sbjct: 725 DAFKCMCPGGWEGTTCNI 742 Score = 53.6 bits (123), Expect = 4e-07 Identities = 23/81 (28%), Positives = 37/81 (45%), Gaps = 1/81 (1%) Frame = +2 Query: 206 NVQNCFTCAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLC-GPGKCM 382 N+ +C PN C N G C + + C+C G+ G C + C P C G C+ Sbjct: 741 NIARNSSCLPNPCHNGGTC--VVNGESFTCVCKEGWEGPICAQNTNDCSPHPCYNSGTCV 798 Query: 383 NTADSYKCACPVTYTGKNCEV 445 + + Y+C C + G +C + Sbjct: 799 DGDNWYRCECAPGFAGPDCRI 819 Score = 53.2 bits (122), Expect = 6e-07 Identities = 23/72 (31%), Positives = 31/72 (43%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLCGPGKCMNTADSYKC 406 C C+N C+ + Y C C PG+ G NCD C C + + Y+C Sbjct: 416 CEAKPCVNAKSCKNLIAS--YYCDCLPGWMGQNCDININDCLGQCQNDASCRDLVNGYRC 473 Query: 407 ACPVTYTGKNCE 442 CP Y G +CE Sbjct: 474 ICPPGYAGDHCE 485 Score = 50.8 bits (116), Expect = 3e-06 Identities = 25/80 (31%), Positives = 36/80 (45%), Gaps = 1/80 (1%) Frame = +2 Query: 203 ENVQNCFTCAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLC-GPGKC 379 +++ C T P CLN G C + Y C C G+ G NC+ +C C G C Sbjct: 295 KDLNYCGTHQP--CLNGGTCSNTGPDK-YQCSCPEGYSGPNCEIAEHACLSDPCHNRGSC 351 Query: 380 MNTADSYKCACPVTYTGKNC 439 T+ ++C C +TG C Sbjct: 352 KETSLGFECECSPGWTGPTC 371 Score = 48.4 bits (110), Expect = 2e-05 Identities = 22/77 (28%), Positives = 34/77 (44%), Gaps = 1/77 (1%) Frame = +2 Query: 212 QNCFTCAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLC-GPGKCMNT 388 +N C N C N G C + + + Y C+C+ G+ G C+ C C G C + Sbjct: 628 ENINDCESNPCRNGGTCIDGV--NSYKCICSDGWEGAYCETNINDCSQNPCHNGGTCRDL 685 Query: 389 ADSYKCACPVTYTGKNC 439 + + C C + GK C Sbjct: 686 VNDFYCDCKNGWKGKTC 702 Score = 43.6 bits (98), Expect = 4e-04 Identities = 22/70 (31%), Positives = 31/70 (44%), Gaps = 1/70 (1%) Frame = +2 Query: 236 NLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLC-GPGKCMNTADSYKCAC 412 N+C +G C+ + + C C GF G C C C G C++ +SYKC C Sbjct: 597 NVCGPHGKCKSQ-SGGKFTCDCNKGFTGTYCHENINDCESNPCRNGGTCIDGVNSYKCIC 655 Query: 413 PVTYTGKNCE 442 + G CE Sbjct: 656 SDGWEGAYCE 665 Score = 37.9 bits (84), Expect = 0.022 Identities = 15/46 (32%), Positives = 20/46 (43%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLC 364 C PN C N C ++ Y C C + G NC + + CR C Sbjct: 529 CEPNPCQNGAQCYNRASD--YFCKCPEDYEGKNCSHLKDHCRTTPC 572 Score = 31.5 bits (68), Expect = 1.9 Identities = 14/46 (30%), Positives = 20/46 (43%), Gaps = 1/46 (2%) Frame = +2 Query: 215 NCFTCAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRI-GESC 349 N C + C C + + +GY C+C PG G C + G C Sbjct: 820 NINECQSSPCAFGATCVDEI--NGYRCVCPPGHSGAKCQEVSGRPC 863 >AL035456-3|CAC07198.1| 1218|Homo sapiens jagged 1 (Alagille syndrome) protein. Length = 1218 Score = 72.1 bits (169), Expect = 1e-12 Identities = 33/72 (45%), Positives = 37/72 (51%), Gaps = 1/72 (1%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLCGPG-KCMNTADSYK 403 CA N CLN G CQ + + CLC GF GN C + C P C G +C N A Y Sbjct: 491 CASNPCLNGGHCQNEINR--FQCLCPTGFSGNLCQLDIDYCEPNPCQNGAQCYNRASDYF 548 Query: 404 CACPVTYTGKNC 439 C CP Y GKNC Sbjct: 549 CKCPEDYEGKNC 560 Score = 64.5 bits (150), Expect = 2e-10 Identities = 27/74 (36%), Positives = 39/74 (52%), Gaps = 1/74 (1%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLCGPG-KCMNTADSYK 403 C + C N G C+E T G+ C C+PG+ G C + C P C G C + + +K Sbjct: 340 CLSDPCHNRGSCKE--TSLGFECECSPGWTGPTCSTNIDDCSPNNCSHGGTCQDLVNGFK 397 Query: 404 CACPVTYTGKNCEV 445 C CP +TGK C++ Sbjct: 398 CVCPPQWTGKTCQL 411 Score = 63.3 bits (147), Expect = 5e-10 Identities = 27/78 (34%), Positives = 42/78 (53%), Gaps = 1/78 (1%) Frame = +2 Query: 212 QNCFTCAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLCGPG-KCMNT 388 QN C+P+ C N+G C + ++ Y C CAPGF G +C C+ C G C++ Sbjct: 781 QNTNDCSPHPCYNSGTCVDG--DNWYRCECAPGFAGPDCRININECQSSPCAFGATCVDE 838 Query: 389 ADSYKCACPVTYTGKNCE 442 + Y+C CP ++G C+ Sbjct: 839 INGYRCVCPPGHSGAKCQ 856 Score = 60.1 bits (139), Expect = 5e-09 Identities = 22/69 (31%), Positives = 40/69 (57%), Gaps = 1/69 (1%) Frame = +2 Query: 242 CLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLC-GPGKCMNTADSYKCACPV 418 C N+ C++ + +GY C+C PG+ G++C+R + C C G C N + ++C CP Sbjct: 458 CQNDASCRDLV--NGYRCICPPGYAGDHCERDIDECASNPCLNGGHCQNEINRFQCLCPT 515 Query: 419 TYTGKNCEV 445 ++G C++ Sbjct: 516 GFSGNLCQL 524 Score = 58.4 bits (135), Expect = 1e-08 Identities = 26/78 (33%), Positives = 38/78 (48%), Gaps = 1/78 (1%) Frame = +2 Query: 215 NCFTCAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLCGPGK-CMNTA 391 N C+PN C + G CQ+ + +G+ C+C P + G C C C K C N Sbjct: 374 NIDDCSPNNCSHGGTCQDLV--NGFKCVCPPQWTGKTCQLDANECEAKPCVNAKSCKNLI 431 Query: 392 DSYKCACPVTYTGKNCEV 445 SY C C + G+NC++ Sbjct: 432 ASYYCDCLPGWMGQNCDI 449 Score = 58.0 bits (134), Expect = 2e-08 Identities = 31/82 (37%), Positives = 43/82 (52%), Gaps = 4/82 (4%) Frame = +2 Query: 218 CFTCAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESC---RPGLCGPGKCMNT 388 C C P+ +G+C E + CLC +GG CD+ C +P L G G C NT Sbjct: 262 CDKCIPHPGCVHGICNEP-----WQCLCETNWGGQLCDKDLNYCGTHQPCLNG-GTCSNT 315 Query: 389 A-DSYKCACPVTYTGKNCEVKQ 451 D Y+C+CP Y+G NCE+ + Sbjct: 316 GPDKYQCSCPEGYSGPNCEIAE 337 Score = 54.4 bits (125), Expect = 2e-07 Identities = 23/78 (29%), Positives = 35/78 (44%), Gaps = 1/78 (1%) Frame = +2 Query: 215 NCFTCAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLCGPG-KCMNTA 391 N C+ N C N G C++ + + + C C G+ G C C C G C + Sbjct: 667 NINDCSQNPCHNGGTCRDLVND--FYCDCKNGWKGKTCHSRDSQCDEATCNNGGTCYDEG 724 Query: 392 DSYKCACPVTYTGKNCEV 445 D++KC CP + G C + Sbjct: 725 DAFKCMCPGGWEGTTCNI 742 Score = 53.6 bits (123), Expect = 4e-07 Identities = 23/81 (28%), Positives = 37/81 (45%), Gaps = 1/81 (1%) Frame = +2 Query: 206 NVQNCFTCAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLC-GPGKCM 382 N+ +C PN C N G C + + C+C G+ G C + C P C G C+ Sbjct: 741 NIARNSSCLPNPCHNGGTC--VVNGESFTCVCKEGWEGPICAQNTNDCSPHPCYNSGTCV 798 Query: 383 NTADSYKCACPVTYTGKNCEV 445 + + Y+C C + G +C + Sbjct: 799 DGDNWYRCECAPGFAGPDCRI 819 Score = 53.2 bits (122), Expect = 6e-07 Identities = 23/72 (31%), Positives = 31/72 (43%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLCGPGKCMNTADSYKC 406 C C+N C+ + Y C C PG+ G NCD C C + + Y+C Sbjct: 416 CEAKPCVNAKSCKNLIAS--YYCDCLPGWMGQNCDININDCLGQCQNDASCRDLVNGYRC 473 Query: 407 ACPVTYTGKNCE 442 CP Y G +CE Sbjct: 474 ICPPGYAGDHCE 485 Score = 50.8 bits (116), Expect = 3e-06 Identities = 25/80 (31%), Positives = 36/80 (45%), Gaps = 1/80 (1%) Frame = +2 Query: 203 ENVQNCFTCAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLC-GPGKC 379 +++ C T P CLN G C + Y C C G+ G NC+ +C C G C Sbjct: 295 KDLNYCGTHQP--CLNGGTCSNTGPDK-YQCSCPEGYSGPNCEIAEHACLSDPCHNRGSC 351 Query: 380 MNTADSYKCACPVTYTGKNC 439 T+ ++C C +TG C Sbjct: 352 KETSLGFECECSPGWTGPTC 371 Score = 48.4 bits (110), Expect = 2e-05 Identities = 22/77 (28%), Positives = 34/77 (44%), Gaps = 1/77 (1%) Frame = +2 Query: 212 QNCFTCAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLC-GPGKCMNT 388 +N C N C N G C + + + Y C+C+ G+ G C+ C C G C + Sbjct: 628 ENINDCESNPCRNGGTCIDGV--NSYKCICSDGWEGAYCETNINDCSQNPCHNGGTCRDL 685 Query: 389 ADSYKCACPVTYTGKNC 439 + + C C + GK C Sbjct: 686 VNDFYCDCKNGWKGKTC 702 Score = 43.6 bits (98), Expect = 4e-04 Identities = 22/70 (31%), Positives = 31/70 (44%), Gaps = 1/70 (1%) Frame = +2 Query: 236 NLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLC-GPGKCMNTADSYKCAC 412 N+C +G C+ + + C C GF G C C C G C++ +SYKC C Sbjct: 597 NVCGPHGKCKSQ-SGGKFTCDCNKGFTGTYCHENINDCESNPCRNGGTCIDGVNSYKCIC 655 Query: 413 PVTYTGKNCE 442 + G CE Sbjct: 656 SDGWEGAYCE 665 Score = 37.9 bits (84), Expect = 0.022 Identities = 15/46 (32%), Positives = 20/46 (43%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLC 364 C PN C N C ++ Y C C + G NC + + CR C Sbjct: 529 CEPNPCQNGAQCYNRASD--YFCKCPEDYEGKNCSHLKDHCRTTPC 572 Score = 31.5 bits (68), Expect = 1.9 Identities = 14/46 (30%), Positives = 20/46 (43%), Gaps = 1/46 (2%) Frame = +2 Query: 215 NCFTCAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRI-GESC 349 N C + C C + + +GY C+C PG G C + G C Sbjct: 820 NINECQSSPCAFGATCVDEI--NGYRCVCPPGHSGAKCQEVSGRPC 863 >AF028593-1|AAB84053.1| 1218|Homo sapiens transmembrane protein Jagged 1 protein. Length = 1218 Score = 72.1 bits (169), Expect = 1e-12 Identities = 33/72 (45%), Positives = 37/72 (51%), Gaps = 1/72 (1%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLCGPG-KCMNTADSYK 403 CA N CLN G CQ + + CLC GF GN C + C P C G +C N A Y Sbjct: 491 CASNPCLNGGHCQNEINR--FQCLCPTGFSGNLCQLDIDYCEPNPCQNGAQCYNRASDYF 548 Query: 404 CACPVTYTGKNC 439 C CP Y GKNC Sbjct: 549 CKCPEDYEGKNC 560 Score = 64.5 bits (150), Expect = 2e-10 Identities = 27/74 (36%), Positives = 39/74 (52%), Gaps = 1/74 (1%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLCGPG-KCMNTADSYK 403 C + C N G C+E T G+ C C+PG+ G C + C P C G C + + +K Sbjct: 340 CLSDPCHNRGSCKE--TSLGFECECSPGWTGPTCSTNIDDCSPNNCSHGGTCQDLVNGFK 397 Query: 404 CACPVTYTGKNCEV 445 C CP +TGK C++ Sbjct: 398 CVCPPQWTGKTCQL 411 Score = 63.3 bits (147), Expect = 5e-10 Identities = 27/78 (34%), Positives = 42/78 (53%), Gaps = 1/78 (1%) Frame = +2 Query: 212 QNCFTCAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLCGPG-KCMNT 388 QN C+P+ C N+G C + ++ Y C CAPGF G +C C+ C G C++ Sbjct: 781 QNTNDCSPHPCYNSGTCVDG--DNWYRCECAPGFAGPDCRININECQSSPCAFGATCVDE 838 Query: 389 ADSYKCACPVTYTGKNCE 442 + Y+C CP ++G C+ Sbjct: 839 INGYRCVCPPGHSGAKCQ 856 Score = 60.1 bits (139), Expect = 5e-09 Identities = 22/69 (31%), Positives = 40/69 (57%), Gaps = 1/69 (1%) Frame = +2 Query: 242 CLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLC-GPGKCMNTADSYKCACPV 418 C N+ C++ + +GY C+C PG+ G++C+R + C C G C N + ++C CP Sbjct: 458 CQNDASCRDLV--NGYRCICPPGYAGDHCERDIDECASNPCLNGGHCQNEINRFQCLCPT 515 Query: 419 TYTGKNCEV 445 ++G C++ Sbjct: 516 GFSGNLCQL 524 Score = 58.4 bits (135), Expect = 1e-08 Identities = 26/78 (33%), Positives = 38/78 (48%), Gaps = 1/78 (1%) Frame = +2 Query: 215 NCFTCAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLCGPGK-CMNTA 391 N C+PN C + G CQ+ + +G+ C+C P + G C C C K C N Sbjct: 374 NIDDCSPNNCSHGGTCQDLV--NGFKCVCPPQWTGKTCQLDANECEAKPCVNAKSCKNLI 431 Query: 392 DSYKCACPVTYTGKNCEV 445 SY C C + G+NC++ Sbjct: 432 ASYYCDCLPGWMGQNCDI 449 Score = 58.0 bits (134), Expect = 2e-08 Identities = 31/82 (37%), Positives = 43/82 (52%), Gaps = 4/82 (4%) Frame = +2 Query: 218 CFTCAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESC---RPGLCGPGKCMNT 388 C C P+ +G+C E + CLC +GG CD+ C +P L G G C NT Sbjct: 262 CDKCIPHPGCVHGICNEP-----WQCLCETNWGGQLCDKDLNYCGTHQPCLNG-GTCSNT 315 Query: 389 A-DSYKCACPVTYTGKNCEVKQ 451 D Y+C+CP Y+G NCE+ + Sbjct: 316 GPDKYQCSCPEGYSGPNCEIAE 337 Score = 54.4 bits (125), Expect = 2e-07 Identities = 23/78 (29%), Positives = 35/78 (44%), Gaps = 1/78 (1%) Frame = +2 Query: 215 NCFTCAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLCGPG-KCMNTA 391 N C+ N C N G C++ + + + C C G+ G C C C G C + Sbjct: 667 NINDCSQNPCHNGGTCRDLVND--FYCDCKNGWKGKTCHSRDSQCDEATCNNGGTCYDEG 724 Query: 392 DSYKCACPVTYTGKNCEV 445 D++KC CP + G C + Sbjct: 725 DAFKCMCPGGWEGTTCNI 742 Score = 53.6 bits (123), Expect = 4e-07 Identities = 23/81 (28%), Positives = 37/81 (45%), Gaps = 1/81 (1%) Frame = +2 Query: 206 NVQNCFTCAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLC-GPGKCM 382 N+ +C PN C N G C + + C+C G+ G C + C P C G C+ Sbjct: 741 NIARNSSCLPNPCHNGGTC--VVNGESFTCVCKEGWEGPICAQNTNDCSPHPCYNSGTCV 798 Query: 383 NTADSYKCACPVTYTGKNCEV 445 + + Y+C C + G +C + Sbjct: 799 DGDNWYRCECAPGFAGPDCRI 819 Score = 53.2 bits (122), Expect = 6e-07 Identities = 23/72 (31%), Positives = 31/72 (43%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLCGPGKCMNTADSYKC 406 C C+N C+ + Y C C PG+ G NCD C C + + Y+C Sbjct: 416 CEAKPCVNAKSCKNLIAS--YYCDCLPGWMGQNCDININDCLGQCQNDASCRDLVNGYRC 473 Query: 407 ACPVTYTGKNCE 442 CP Y G +CE Sbjct: 474 ICPPGYAGDHCE 485 Score = 50.8 bits (116), Expect = 3e-06 Identities = 25/80 (31%), Positives = 36/80 (45%), Gaps = 1/80 (1%) Frame = +2 Query: 203 ENVQNCFTCAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLC-GPGKC 379 +++ C T P CLN G C + Y C C G+ G NC+ +C C G C Sbjct: 295 KDLNYCGTHQP--CLNGGTCSNTGPDK-YQCSCPEGYSGPNCEIAEHACLSDPCHNRGSC 351 Query: 380 MNTADSYKCACPVTYTGKNC 439 T+ ++C C +TG C Sbjct: 352 KETSLGFECECSPGWTGPTC 371 Score = 48.4 bits (110), Expect = 2e-05 Identities = 22/77 (28%), Positives = 34/77 (44%), Gaps = 1/77 (1%) Frame = +2 Query: 212 QNCFTCAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLC-GPGKCMNT 388 +N C N C N G C + + + Y C+C+ G+ G C+ C C G C + Sbjct: 628 ENINDCESNPCRNGGTCIDGV--NSYKCICSDGWEGAYCETNINDCSQNPCHNGGTCRDL 685 Query: 389 ADSYKCACPVTYTGKNC 439 + + C C + GK C Sbjct: 686 VNDFYCDCKNGWKGKTC 702 Score = 43.6 bits (98), Expect = 4e-04 Identities = 22/70 (31%), Positives = 31/70 (44%), Gaps = 1/70 (1%) Frame = +2 Query: 236 NLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLC-GPGKCMNTADSYKCAC 412 N+C +G C+ + + C C GF G C C C G C++ +SYKC C Sbjct: 597 NVCGPHGKCKSQ-SGGKFTCDCNKGFTGTYCHENINDCESNPCRNGGTCIDGVNSYKCIC 655 Query: 413 PVTYTGKNCE 442 + G CE Sbjct: 656 SDGWEGAYCE 665 Score = 37.9 bits (84), Expect = 0.022 Identities = 15/46 (32%), Positives = 20/46 (43%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLC 364 C PN C N C ++ Y C C + G NC + + CR C Sbjct: 529 CEPNPCQNGAQCYNRASD--YFCKCPEDYEGKNCSHLKDHCRTTPC 572 Score = 31.5 bits (68), Expect = 1.9 Identities = 14/46 (30%), Positives = 20/46 (43%), Gaps = 1/46 (2%) Frame = +2 Query: 215 NCFTCAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRI-GESC 349 N C + C C + + +GY C+C PG G C + G C Sbjct: 820 NINECQSSPCAFGATCVDEI--NGYRCVCPPGHSGAKCQEVSGRPC 863 >BC146761-1|AAI46762.1| 1534|Homo sapiens slit homolog 1 (Drosophila) protein. Length = 1534 Score = 71.3 bits (167), Expect = 2e-12 Identities = 47/152 (30%), Positives = 69/152 (45%), Gaps = 6/152 (3%) Frame = +2 Query: 2 DNSGPFIAESPDQWTVLELNQPLYIGGVP-DFDQLPIDL---AGASGFVGCISMLILGNE 169 D P ++ + L PLY+GG+P D + L +GF GCI L + NE Sbjct: 1263 DGGSPMTMDNFGKHYTLNSEAPLYVGGMPVDVNSAAFRLWQILNGTGFHGCIRNLYINNE 1322 Query: 170 EKNIMALALEKENVQNCFTCAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGES- 346 ++ ++ V C C CL +G+CQ T G +C C G+ G +CD+ + Sbjct: 1323 LQDFTKTQMKPGVVPGCEPCRKLYCL-HGICQPNATP-GPMCHCEAGWVGLHCDQPADGP 1380 Query: 347 CRPGLCGPGKCMN-TADSYKCACPVTYTGKNC 439 C C G+C+ A SY C C Y+G C Sbjct: 1381 CHGHKCVHGQCVPLDALSYSCQCQDGYSGALC 1412 Score = 59.3 bits (137), Expect = 8e-09 Identities = 29/83 (34%), Positives = 42/83 (50%), Gaps = 3/83 (3%) Frame = +2 Query: 227 CAPNL--CLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLCGPG-KCMNTADS 397 C+P+L C + C T G C C PG+ G+NC + CR C G +CM+ +S Sbjct: 1047 CSPDLNPCQHEAQCVG--TPDGPRCECMPGYAGDNCSENQDDCRDHRCQNGAQCMDEVNS 1104 Query: 398 YKCACPVTYTGKNCEVKQLIEYP 466 Y C C Y+G+ CE+ + P Sbjct: 1105 YSCLCAEGYSGQLCEIPPHLPAP 1127 Score = 54.0 bits (124), Expect = 3e-07 Identities = 27/81 (33%), Positives = 37/81 (45%), Gaps = 2/81 (2%) Frame = +2 Query: 224 TCAPNLCLNNGVCQEALTEHG-YVCLCAPGFGGNNCDRIGESCRPGLCGPGK-CMNTADS 397 +C+ C N G C E + C C GF G C + C C G C++ + Sbjct: 967 SCSSGPCENGGTCHAQEGEDAPFTCSCPTGFEGPTCGVNTDDCVDHACANGGVCVDGVGN 1026 Query: 398 YKCACPVTYTGKNCEVKQLIE 460 Y C CP+ Y GK CE QL++ Sbjct: 1027 YTCQCPLQYEGKACE--QLVD 1045 Score = 53.2 bits (122), Expect = 6e-07 Identities = 26/82 (31%), Positives = 37/82 (45%), Gaps = 3/82 (3%) Frame = +2 Query: 215 NCFTCAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGL--C-GPGKCMN 385 N C + C N GVC + + Y C C + G C+++ + C P L C +C+ Sbjct: 1005 NTDDCVDHACANGGVCVDGVGN--YTCQCPLQYEGKACEQLVDLCSPDLNPCQHEAQCVG 1062 Query: 386 TADSYKCACPVTYTGKNCEVKQ 451 T D +C C Y G NC Q Sbjct: 1063 TPDGPRCECMPGYAGDNCSENQ 1084 Score = 48.4 bits (110), Expect = 2e-05 Identities = 24/80 (30%), Positives = 34/80 (42%), Gaps = 4/80 (5%) Frame = +2 Query: 218 CFTCAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLCGPGKCMNTADS 397 C C + C N G C E Y C C G+ G +C+ +SC G C G + + Sbjct: 926 CDLCLSSPCQNQGTCHNDPLEV-YRCACPSGYKGRDCEVSLDSCSSGPCENGGTCHAQEG 984 Query: 398 ----YKCACPVTYTGKNCEV 445 + C+CP + G C V Sbjct: 985 EDAPFTCSCPTGFEGPTCGV 1004 Score = 31.9 bits (69), Expect = 1.5 Identities = 18/42 (42%), Positives = 24/42 (57%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCR 352 C CL+ G CQ + T+ G C+C PGF G C++ E CR Sbjct: 1422 CRGLQCLH-GHCQASGTK-GAHCVCDPGFSGELCEQESE-CR 1460 Score = 30.3 bits (65), Expect = 4.5 Identities = 13/37 (35%), Positives = 17/37 (45%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRI 337 C C N C + VC C PGFGG C+++ Sbjct: 1131 CEGTECQNGANCVDQGNRP--VCQCLPGFGGPECEKL 1165 >AL512424-5|CAI14258.1| 1534|Homo sapiens slit homolog 1 (Drosophila) protein. Length = 1534 Score = 71.3 bits (167), Expect = 2e-12 Identities = 47/152 (30%), Positives = 69/152 (45%), Gaps = 6/152 (3%) Frame = +2 Query: 2 DNSGPFIAESPDQWTVLELNQPLYIGGVP-DFDQLPIDL---AGASGFVGCISMLILGNE 169 D P ++ + L PLY+GG+P D + L +GF GCI L + NE Sbjct: 1263 DGGSPMTMDNFGKHYTLNSEAPLYVGGMPVDVNSAAFRLWQILNGTGFHGCIRNLYINNE 1322 Query: 170 EKNIMALALEKENVQNCFTCAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGES- 346 ++ ++ V C C CL +G+CQ T G +C C G+ G +CD+ + Sbjct: 1323 LQDFTKTQMKPGVVPGCEPCRKLYCL-HGICQPNATP-GPMCHCEAGWVGLHCDQPADGP 1380 Query: 347 CRPGLCGPGKCMN-TADSYKCACPVTYTGKNC 439 C C G+C+ A SY C C Y+G C Sbjct: 1381 CHGHKCVHGQCVPLDALSYSCQCQDGYSGALC 1412 Score = 59.3 bits (137), Expect = 8e-09 Identities = 29/83 (34%), Positives = 42/83 (50%), Gaps = 3/83 (3%) Frame = +2 Query: 227 CAPNL--CLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLCGPG-KCMNTADS 397 C+P+L C + C T G C C PG+ G+NC + CR C G +CM+ +S Sbjct: 1047 CSPDLNPCQHEAQCVG--TPDGPRCECMPGYAGDNCSENQDDCRDHRCQNGAQCMDEVNS 1104 Query: 398 YKCACPVTYTGKNCEVKQLIEYP 466 Y C C Y+G+ CE+ + P Sbjct: 1105 YSCLCAEGYSGQLCEIPPHLPAP 1127 Score = 54.0 bits (124), Expect = 3e-07 Identities = 27/81 (33%), Positives = 37/81 (45%), Gaps = 2/81 (2%) Frame = +2 Query: 224 TCAPNLCLNNGVCQEALTEHG-YVCLCAPGFGGNNCDRIGESCRPGLCGPGK-CMNTADS 397 +C+ C N G C E + C C GF G C + C C G C++ + Sbjct: 967 SCSSGPCENGGTCHAQEGEDAPFTCSCPTGFEGPTCGVNTDDCVDHACANGGVCVDGVGN 1026 Query: 398 YKCACPVTYTGKNCEVKQLIE 460 Y C CP+ Y GK CE QL++ Sbjct: 1027 YTCQCPLQYEGKACE--QLVD 1045 Score = 53.2 bits (122), Expect = 6e-07 Identities = 26/82 (31%), Positives = 37/82 (45%), Gaps = 3/82 (3%) Frame = +2 Query: 215 NCFTCAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGL--C-GPGKCMN 385 N C + C N GVC + + Y C C + G C+++ + C P L C +C+ Sbjct: 1005 NTDDCVDHACANGGVCVDGVGN--YTCQCPLQYEGKACEQLVDLCSPDLNPCQHEAQCVG 1062 Query: 386 TADSYKCACPVTYTGKNCEVKQ 451 T D +C C Y G NC Q Sbjct: 1063 TPDGPRCECMPGYAGDNCSENQ 1084 Score = 48.4 bits (110), Expect = 2e-05 Identities = 24/80 (30%), Positives = 34/80 (42%), Gaps = 4/80 (5%) Frame = +2 Query: 218 CFTCAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLCGPGKCMNTADS 397 C C + C N G C E Y C C G+ G +C+ +SC G C G + + Sbjct: 926 CDLCLSSPCQNQGTCHNDPLEV-YRCACPSGYKGRDCEVSLDSCSSGPCENGGTCHAQEG 984 Query: 398 ----YKCACPVTYTGKNCEV 445 + C+CP + G C V Sbjct: 985 EDAPFTCSCPTGFEGPTCGV 1004 Score = 31.9 bits (69), Expect = 1.5 Identities = 18/42 (42%), Positives = 24/42 (57%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCR 352 C CL+ G CQ + T+ G C+C PGF G C++ E CR Sbjct: 1422 CRGLQCLH-GHCQASGTK-GAHCVCDPGFSGELCEQESE-CR 1460 Score = 30.3 bits (65), Expect = 4.5 Identities = 13/37 (35%), Positives = 17/37 (45%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRI 337 C C N C + VC C PGFGG C+++ Sbjct: 1131 CEGTECQNGANCVDQGNRP--VCQCLPGFGGPECEKL 1165 >AL512424-4|CAI14259.1| 1461|Homo sapiens slit homolog 1 (Drosophila) protein. Length = 1461 Score = 71.3 bits (167), Expect = 2e-12 Identities = 47/152 (30%), Positives = 69/152 (45%), Gaps = 6/152 (3%) Frame = +2 Query: 2 DNSGPFIAESPDQWTVLELNQPLYIGGVP-DFDQLPIDL---AGASGFVGCISMLILGNE 169 D P ++ + L PLY+GG+P D + L +GF GCI L + NE Sbjct: 1263 DGGSPMTMDNFGKHYTLNSEAPLYVGGMPVDVNSAAFRLWQILNGTGFHGCIRNLYINNE 1322 Query: 170 EKNIMALALEKENVQNCFTCAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGES- 346 ++ ++ V C C CL +G+CQ T G +C C G+ G +CD+ + Sbjct: 1323 LQDFTKTQMKPGVVPGCEPCRKLYCL-HGICQPNATP-GPMCHCEAGWVGLHCDQPADGP 1380 Query: 347 CRPGLCGPGKCMN-TADSYKCACPVTYTGKNC 439 C C G+C+ A SY C C Y+G C Sbjct: 1381 CHGHKCVHGQCVPLDALSYSCQCQDGYSGALC 1412 Score = 59.3 bits (137), Expect = 8e-09 Identities = 29/83 (34%), Positives = 42/83 (50%), Gaps = 3/83 (3%) Frame = +2 Query: 227 CAPNL--CLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLCGPG-KCMNTADS 397 C+P+L C + C T G C C PG+ G+NC + CR C G +CM+ +S Sbjct: 1047 CSPDLNPCQHEAQCVG--TPDGPRCECMPGYAGDNCSENQDDCRDHRCQNGAQCMDEVNS 1104 Query: 398 YKCACPVTYTGKNCEVKQLIEYP 466 Y C C Y+G+ CE+ + P Sbjct: 1105 YSCLCAEGYSGQLCEIPPHLPAP 1127 Score = 54.0 bits (124), Expect = 3e-07 Identities = 27/81 (33%), Positives = 37/81 (45%), Gaps = 2/81 (2%) Frame = +2 Query: 224 TCAPNLCLNNGVCQEALTEHG-YVCLCAPGFGGNNCDRIGESCRPGLCGPGK-CMNTADS 397 +C+ C N G C E + C C GF G C + C C G C++ + Sbjct: 967 SCSSGPCENGGTCHAQEGEDAPFTCSCPTGFEGPTCGVNTDDCVDHACANGGVCVDGVGN 1026 Query: 398 YKCACPVTYTGKNCEVKQLIE 460 Y C CP+ Y GK CE QL++ Sbjct: 1027 YTCQCPLQYEGKACE--QLVD 1045 Score = 53.2 bits (122), Expect = 6e-07 Identities = 26/82 (31%), Positives = 37/82 (45%), Gaps = 3/82 (3%) Frame = +2 Query: 215 NCFTCAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGL--C-GPGKCMN 385 N C + C N GVC + + Y C C + G C+++ + C P L C +C+ Sbjct: 1005 NTDDCVDHACANGGVCVDGVGN--YTCQCPLQYEGKACEQLVDLCSPDLNPCQHEAQCVG 1062 Query: 386 TADSYKCACPVTYTGKNCEVKQ 451 T D +C C Y G NC Q Sbjct: 1063 TPDGPRCECMPGYAGDNCSENQ 1084 Score = 48.4 bits (110), Expect = 2e-05 Identities = 24/80 (30%), Positives = 34/80 (42%), Gaps = 4/80 (5%) Frame = +2 Query: 218 CFTCAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLCGPGKCMNTADS 397 C C + C N G C E Y C C G+ G +C+ +SC G C G + + Sbjct: 926 CDLCLSSPCQNQGTCHNDPLEV-YRCACPSGYKGRDCEVSLDSCSSGPCENGGTCHAQEG 984 Query: 398 ----YKCACPVTYTGKNCEV 445 + C+CP + G C V Sbjct: 985 EDAPFTCSCPTGFEGPTCGV 1004 Score = 30.3 bits (65), Expect = 4.5 Identities = 13/37 (35%), Positives = 17/37 (45%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRI 337 C C N C + VC C PGFGG C+++ Sbjct: 1131 CEGTECQNGANCVDQGNRP--VCQCLPGFGGPECEKL 1165 >AL442123-4|CAH70918.1| 1534|Homo sapiens slit homolog 1 (Drosophila) protein. Length = 1534 Score = 71.3 bits (167), Expect = 2e-12 Identities = 47/152 (30%), Positives = 69/152 (45%), Gaps = 6/152 (3%) Frame = +2 Query: 2 DNSGPFIAESPDQWTVLELNQPLYIGGVP-DFDQLPIDL---AGASGFVGCISMLILGNE 169 D P ++ + L PLY+GG+P D + L +GF GCI L + NE Sbjct: 1263 DGGSPMTMDNFGKHYTLNSEAPLYVGGMPVDVNSAAFRLWQILNGTGFHGCIRNLYINNE 1322 Query: 170 EKNIMALALEKENVQNCFTCAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGES- 346 ++ ++ V C C CL +G+CQ T G +C C G+ G +CD+ + Sbjct: 1323 LQDFTKTQMKPGVVPGCEPCRKLYCL-HGICQPNATP-GPMCHCEAGWVGLHCDQPADGP 1380 Query: 347 CRPGLCGPGKCMN-TADSYKCACPVTYTGKNC 439 C C G+C+ A SY C C Y+G C Sbjct: 1381 CHGHKCVHGQCVPLDALSYSCQCQDGYSGALC 1412 Score = 59.3 bits (137), Expect = 8e-09 Identities = 29/83 (34%), Positives = 42/83 (50%), Gaps = 3/83 (3%) Frame = +2 Query: 227 CAPNL--CLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLCGPG-KCMNTADS 397 C+P+L C + C T G C C PG+ G+NC + CR C G +CM+ +S Sbjct: 1047 CSPDLNPCQHEAQCVG--TPDGPRCECMPGYAGDNCSENQDDCRDHRCQNGAQCMDEVNS 1104 Query: 398 YKCACPVTYTGKNCEVKQLIEYP 466 Y C C Y+G+ CE+ + P Sbjct: 1105 YSCLCAEGYSGQLCEIPPHLPAP 1127 Score = 54.0 bits (124), Expect = 3e-07 Identities = 27/81 (33%), Positives = 37/81 (45%), Gaps = 2/81 (2%) Frame = +2 Query: 224 TCAPNLCLNNGVCQEALTEHG-YVCLCAPGFGGNNCDRIGESCRPGLCGPGK-CMNTADS 397 +C+ C N G C E + C C GF G C + C C G C++ + Sbjct: 967 SCSSGPCENGGTCHAQEGEDAPFTCSCPTGFEGPTCGVNTDDCVDHACANGGVCVDGVGN 1026 Query: 398 YKCACPVTYTGKNCEVKQLIE 460 Y C CP+ Y GK CE QL++ Sbjct: 1027 YTCQCPLQYEGKACE--QLVD 1045 Score = 53.2 bits (122), Expect = 6e-07 Identities = 26/82 (31%), Positives = 37/82 (45%), Gaps = 3/82 (3%) Frame = +2 Query: 215 NCFTCAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGL--C-GPGKCMN 385 N C + C N GVC + + Y C C + G C+++ + C P L C +C+ Sbjct: 1005 NTDDCVDHACANGGVCVDGVGN--YTCQCPLQYEGKACEQLVDLCSPDLNPCQHEAQCVG 1062 Query: 386 TADSYKCACPVTYTGKNCEVKQ 451 T D +C C Y G NC Q Sbjct: 1063 TPDGPRCECMPGYAGDNCSENQ 1084 Score = 48.4 bits (110), Expect = 2e-05 Identities = 24/80 (30%), Positives = 34/80 (42%), Gaps = 4/80 (5%) Frame = +2 Query: 218 CFTCAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLCGPGKCMNTADS 397 C C + C N G C E Y C C G+ G +C+ +SC G C G + + Sbjct: 926 CDLCLSSPCQNQGTCHNDPLEV-YRCACPSGYKGRDCEVSLDSCSSGPCENGGTCHAQEG 984 Query: 398 ----YKCACPVTYTGKNCEV 445 + C+CP + G C V Sbjct: 985 EDAPFTCSCPTGFEGPTCGV 1004 Score = 31.9 bits (69), Expect = 1.5 Identities = 18/42 (42%), Positives = 24/42 (57%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCR 352 C CL+ G CQ + T+ G C+C PGF G C++ E CR Sbjct: 1422 CRGLQCLH-GHCQASGTK-GAHCVCDPGFSGELCEQESE-CR 1460 Score = 30.3 bits (65), Expect = 4.5 Identities = 13/37 (35%), Positives = 17/37 (45%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRI 337 C C N C + VC C PGFGG C+++ Sbjct: 1131 CEGTECQNGANCVDQGNRP--VCQCLPGFGGPECEKL 1165 >AL442123-3|CAH70917.1| 1461|Homo sapiens slit homolog 1 (Drosophila) protein. Length = 1461 Score = 71.3 bits (167), Expect = 2e-12 Identities = 47/152 (30%), Positives = 69/152 (45%), Gaps = 6/152 (3%) Frame = +2 Query: 2 DNSGPFIAESPDQWTVLELNQPLYIGGVP-DFDQLPIDL---AGASGFVGCISMLILGNE 169 D P ++ + L PLY+GG+P D + L +GF GCI L + NE Sbjct: 1263 DGGSPMTMDNFGKHYTLNSEAPLYVGGMPVDVNSAAFRLWQILNGTGFHGCIRNLYINNE 1322 Query: 170 EKNIMALALEKENVQNCFTCAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGES- 346 ++ ++ V C C CL +G+CQ T G +C C G+ G +CD+ + Sbjct: 1323 LQDFTKTQMKPGVVPGCEPCRKLYCL-HGICQPNATP-GPMCHCEAGWVGLHCDQPADGP 1380 Query: 347 CRPGLCGPGKCMN-TADSYKCACPVTYTGKNC 439 C C G+C+ A SY C C Y+G C Sbjct: 1381 CHGHKCVHGQCVPLDALSYSCQCQDGYSGALC 1412 Score = 59.3 bits (137), Expect = 8e-09 Identities = 29/83 (34%), Positives = 42/83 (50%), Gaps = 3/83 (3%) Frame = +2 Query: 227 CAPNL--CLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLCGPG-KCMNTADS 397 C+P+L C + C T G C C PG+ G+NC + CR C G +CM+ +S Sbjct: 1047 CSPDLNPCQHEAQCVG--TPDGPRCECMPGYAGDNCSENQDDCRDHRCQNGAQCMDEVNS 1104 Query: 398 YKCACPVTYTGKNCEVKQLIEYP 466 Y C C Y+G+ CE+ + P Sbjct: 1105 YSCLCAEGYSGQLCEIPPHLPAP 1127 Score = 54.0 bits (124), Expect = 3e-07 Identities = 27/81 (33%), Positives = 37/81 (45%), Gaps = 2/81 (2%) Frame = +2 Query: 224 TCAPNLCLNNGVCQEALTEHG-YVCLCAPGFGGNNCDRIGESCRPGLCGPGK-CMNTADS 397 +C+ C N G C E + C C GF G C + C C G C++ + Sbjct: 967 SCSSGPCENGGTCHAQEGEDAPFTCSCPTGFEGPTCGVNTDDCVDHACANGGVCVDGVGN 1026 Query: 398 YKCACPVTYTGKNCEVKQLIE 460 Y C CP+ Y GK CE QL++ Sbjct: 1027 YTCQCPLQYEGKACE--QLVD 1045 Score = 53.2 bits (122), Expect = 6e-07 Identities = 26/82 (31%), Positives = 37/82 (45%), Gaps = 3/82 (3%) Frame = +2 Query: 215 NCFTCAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGL--C-GPGKCMN 385 N C + C N GVC + + Y C C + G C+++ + C P L C +C+ Sbjct: 1005 NTDDCVDHACANGGVCVDGVGN--YTCQCPLQYEGKACEQLVDLCSPDLNPCQHEAQCVG 1062 Query: 386 TADSYKCACPVTYTGKNCEVKQ 451 T D +C C Y G NC Q Sbjct: 1063 TPDGPRCECMPGYAGDNCSENQ 1084 Score = 48.4 bits (110), Expect = 2e-05 Identities = 24/80 (30%), Positives = 34/80 (42%), Gaps = 4/80 (5%) Frame = +2 Query: 218 CFTCAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLCGPGKCMNTADS 397 C C + C N G C E Y C C G+ G +C+ +SC G C G + + Sbjct: 926 CDLCLSSPCQNQGTCHNDPLEV-YRCACPSGYKGRDCEVSLDSCSSGPCENGGTCHAQEG 984 Query: 398 ----YKCACPVTYTGKNCEV 445 + C+CP + G C V Sbjct: 985 EDAPFTCSCPTGFEGPTCGV 1004 Score = 30.3 bits (65), Expect = 4.5 Identities = 13/37 (35%), Positives = 17/37 (45%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRI 337 C C N C + VC C PGFGG C+++ Sbjct: 1131 CEGTECQNGANCVDQGNRP--VCQCLPGFGGPECEKL 1165 >AL050329-2|CAB99359.1| 399|Homo sapiens protein ( Human DNA sequence from clone RP1-22I17 on chromosome 6q11.1-12 Contains the 3' end of the PHF3 gene for PHD finger protein 3. ). Length = 399 Score = 71.3 bits (167), Expect = 2e-12 Identities = 51/169 (30%), Positives = 78/169 (46%), Gaps = 8/169 (4%) Frame = +2 Query: 50 LELNQPLYIGGVPDFDQL-PIDLAGAS-GFVGCISMLILGNEEKNIMALALEK-ENVQNC 220 L+ N YIGGV + + P+ + GF GCI +I+ N+E + + NV +C Sbjct: 70 LDTNTDFYIGGVSSLNLVNPMAIENEPVGFQGCIRQVIINNQELQLTEFGAKGGSNVGDC 129 Query: 221 --FTCAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLC-GPGKCM-NT 388 C N C N G C T + C C P + GN C++ SC LC C+ + Sbjct: 130 DGTACGYNTCRNGGECTVNGTT--FSCRCLPDWAGNTCNQ-SVSCLNNLCLHQSLCIPDQ 186 Query: 389 ADSYKCACPVTYTGKNCEVKQLIEYPAFTGSA*LA-IKPPTSTRSLKMS 532 + SY C C + + G+ CE K F G++ + I P R+L+ + Sbjct: 187 SFSYSCLCTLGWVGRYCENKTSFSTAKFMGNSYIKYIDPNYRMRNLQFT 235 >AB017167-1|BAA35184.1| 1534|Homo sapiens Slit-1 protein protein. Length = 1534 Score = 71.3 bits (167), Expect = 2e-12 Identities = 47/152 (30%), Positives = 69/152 (45%), Gaps = 6/152 (3%) Frame = +2 Query: 2 DNSGPFIAESPDQWTVLELNQPLYIGGVP-DFDQLPIDL---AGASGFVGCISMLILGNE 169 D P ++ + L PLY+GG+P D + L +GF GCI L + NE Sbjct: 1263 DGGSPMTMDNFGKHYTLNSEAPLYVGGMPVDVNSAAFRLWQILNGTGFHGCIRNLYINNE 1322 Query: 170 EKNIMALALEKENVQNCFTCAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGES- 346 ++ ++ V C C CL +G+CQ T G +C C G+ G +CD+ + Sbjct: 1323 LQDFTKTQMKPGVVPGCEPCRKLYCL-HGICQPNATP-GPMCHCEAGWVGLHCDQPADGP 1380 Query: 347 CRPGLCGPGKCMN-TADSYKCACPVTYTGKNC 439 C C G+C+ A SY C C Y+G C Sbjct: 1381 CHGHKCVHGQCVPLDALSYSCQCQDGYSGALC 1412 Score = 59.3 bits (137), Expect = 8e-09 Identities = 29/83 (34%), Positives = 42/83 (50%), Gaps = 3/83 (3%) Frame = +2 Query: 227 CAPNL--CLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLCGPG-KCMNTADS 397 C+P+L C + C T G C C PG+ G+NC + CR C G +CM+ +S Sbjct: 1047 CSPDLNPCQHEAQCVG--TPDGPRCECMPGYAGDNCSENQDDCRDHRCQNGAQCMDEVNS 1104 Query: 398 YKCACPVTYTGKNCEVKQLIEYP 466 Y C C Y+G+ CE+ + P Sbjct: 1105 YSCLCAEGYSGQLCEIPPHLPAP 1127 Score = 54.0 bits (124), Expect = 3e-07 Identities = 27/81 (33%), Positives = 37/81 (45%), Gaps = 2/81 (2%) Frame = +2 Query: 224 TCAPNLCLNNGVCQEALTEHG-YVCLCAPGFGGNNCDRIGESCRPGLCGPGK-CMNTADS 397 +C+ C N G C E + C C GF G C + C C G C++ + Sbjct: 967 SCSSGPCENGGTCHAQEGEDAPFTCSCPTGFEGPTCGVNTDDCVDHACANGGVCVDGVGN 1026 Query: 398 YKCACPVTYTGKNCEVKQLIE 460 Y C CP+ Y GK CE QL++ Sbjct: 1027 YTCQCPLQYEGKACE--QLVD 1045 Score = 53.2 bits (122), Expect = 6e-07 Identities = 26/82 (31%), Positives = 37/82 (45%), Gaps = 3/82 (3%) Frame = +2 Query: 215 NCFTCAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGL--C-GPGKCMN 385 N C + C N GVC + + Y C C + G C+++ + C P L C +C+ Sbjct: 1005 NTDDCVDHACANGGVCVDGVGN--YTCQCPLQYEGKACEQLVDLCSPDLNPCQHEAQCVG 1062 Query: 386 TADSYKCACPVTYTGKNCEVKQ 451 T D +C C Y G NC Q Sbjct: 1063 TPDGPRCECMPGYAGDNCSENQ 1084 Score = 47.6 bits (108), Expect = 3e-05 Identities = 24/80 (30%), Positives = 33/80 (41%), Gaps = 4/80 (5%) Frame = +2 Query: 218 CFTCAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLCGPGKCMNTADS 397 C C + C N G C E Y C C G+ G +C+ SC G C G + + Sbjct: 926 CDLCLSSPCQNQGTCHNDPLEV-YRCACPSGYKGRDCEVSLNSCSSGPCENGGTCHAQEG 984 Query: 398 ----YKCACPVTYTGKNCEV 445 + C+CP + G C V Sbjct: 985 EDAPFTCSCPTGFEGPTCGV 1004 Score = 31.9 bits (69), Expect = 1.5 Identities = 18/42 (42%), Positives = 24/42 (57%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCR 352 C CL+ G CQ + T+ G C+C PGF G C++ E CR Sbjct: 1422 CRGLQCLH-GHCQASGTK-GAHCVCDPGFSGELCEQESE-CR 1460 Score = 30.3 bits (65), Expect = 4.5 Identities = 13/37 (35%), Positives = 17/37 (45%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRI 337 C C N C + VC C PGFGG C+++ Sbjct: 1131 CEGTECQNGANCVDQGNRP--VCQCLPGFGGPECEKL 1165 >AB011537-1|BAA32465.3| 1618|Homo sapiens MEGF4 protein. Length = 1618 Score = 71.3 bits (167), Expect = 2e-12 Identities = 47/152 (30%), Positives = 69/152 (45%), Gaps = 6/152 (3%) Frame = +2 Query: 2 DNSGPFIAESPDQWTVLELNQPLYIGGVP-DFDQLPIDL---AGASGFVGCISMLILGNE 169 D P ++ + L PLY+GG+P D + L +GF GCI L + NE Sbjct: 1347 DGGSPMTMDNFGKHYTLNSEAPLYVGGMPVDVNSAAFRLWQILNGTGFHGCIRNLYINNE 1406 Query: 170 EKNIMALALEKENVQNCFTCAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGES- 346 ++ ++ V C C CL +G+CQ T G +C C G+ G +CD+ + Sbjct: 1407 LQDFTKTQMKPGVVPGCEPCRKLYCL-HGICQPNATP-GPMCHCEAGWVGLHCDQPADGP 1464 Query: 347 CRPGLCGPGKCMN-TADSYKCACPVTYTGKNC 439 C C G+C+ A SY C C Y+G C Sbjct: 1465 CHGHKCVHGQCVPLDALSYSCQCQDGYSGALC 1496 Score = 59.3 bits (137), Expect = 8e-09 Identities = 29/83 (34%), Positives = 42/83 (50%), Gaps = 3/83 (3%) Frame = +2 Query: 227 CAPNL--CLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLCGPG-KCMNTADS 397 C+P+L C + C T G C C PG+ G+NC + CR C G +CM+ +S Sbjct: 1131 CSPDLNPCQHEAQCVG--TPDGPRCECMPGYAGDNCSENQDDCRDHRCQNGAQCMDEVNS 1188 Query: 398 YKCACPVTYTGKNCEVKQLIEYP 466 Y C C Y+G+ CE+ + P Sbjct: 1189 YSCLCAEGYSGQLCEIPPHLPAP 1211 Score = 54.0 bits (124), Expect = 3e-07 Identities = 27/81 (33%), Positives = 37/81 (45%), Gaps = 2/81 (2%) Frame = +2 Query: 224 TCAPNLCLNNGVCQEALTEHG-YVCLCAPGFGGNNCDRIGESCRPGLCGPGK-CMNTADS 397 +C+ C N G C E + C C GF G C + C C G C++ + Sbjct: 1051 SCSSGPCENGGTCHAQEGEDAPFTCSCPTGFEGPTCGVNTDDCVDHACANGGVCVDGVGN 1110 Query: 398 YKCACPVTYTGKNCEVKQLIE 460 Y C CP+ Y GK CE QL++ Sbjct: 1111 YTCQCPLQYEGKACE--QLVD 1129 Score = 53.2 bits (122), Expect = 6e-07 Identities = 26/82 (31%), Positives = 37/82 (45%), Gaps = 3/82 (3%) Frame = +2 Query: 215 NCFTCAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGL--C-GPGKCMN 385 N C + C N GVC + + Y C C + G C+++ + C P L C +C+ Sbjct: 1089 NTDDCVDHACANGGVCVDGVGN--YTCQCPLQYEGKACEQLVDLCSPDLNPCQHEAQCVG 1146 Query: 386 TADSYKCACPVTYTGKNCEVKQ 451 T D +C C Y G NC Q Sbjct: 1147 TPDGPRCECMPGYAGDNCSENQ 1168 Score = 48.4 bits (110), Expect = 2e-05 Identities = 24/80 (30%), Positives = 34/80 (42%), Gaps = 4/80 (5%) Frame = +2 Query: 218 CFTCAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLCGPGKCMNTADS 397 C C + C N G C E Y C C G+ G +C+ +SC G C G + + Sbjct: 1010 CDLCLSSPCQNQGTCHNDPLEV-YRCACPSGYKGRDCEVSLDSCSSGPCENGGTCHAQEG 1068 Query: 398 ----YKCACPVTYTGKNCEV 445 + C+CP + G C V Sbjct: 1069 EDAPFTCSCPTGFEGPTCGV 1088 Score = 31.9 bits (69), Expect = 1.5 Identities = 18/42 (42%), Positives = 24/42 (57%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCR 352 C CL+ G CQ + T+ G C+C PGF G C++ E CR Sbjct: 1506 CRGLQCLH-GHCQASGTK-GAHCVCDPGFSGELCEQESE-CR 1544 Score = 30.3 bits (65), Expect = 4.5 Identities = 13/37 (35%), Positives = 17/37 (45%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRI 337 C C N C + VC C PGFGG C+++ Sbjct: 1215 CEGTECQNGANCVDQGNRP--VCQCLPGFGGPECEKL 1249 >BC071562-1|AAH71562.2| 1235|Homo sapiens NOTCH2 protein protein. Length = 1235 Score = 70.9 bits (166), Expect = 3e-12 Identities = 34/82 (41%), Positives = 43/82 (52%), Gaps = 5/82 (6%) Frame = +2 Query: 212 QNCFT----CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLC-GPGK 376 +NC T C+PN C N VC+E+ Y CLCAPG+ G C + C C G Sbjct: 828 KNCQTVLAPCSPNPCENAAVCKESPNFESYTCLCAPGWQGQRCTIDIDECISKPCMNHGL 887 Query: 377 CMNTADSYKCACPVTYTGKNCE 442 C NT SY C CP ++G +CE Sbjct: 888 CHNTQGSYMCECPPGFSGMDCE 909 Score = 63.7 bits (148), Expect = 4e-10 Identities = 26/72 (36%), Positives = 41/72 (56%), Gaps = 1/72 (1%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLC-GPGKCMNTADSYK 403 CAP+ C+N G C++ + + C C PGF G+ C+R + C C G C++ ++Y Sbjct: 225 CAPSPCVNGGTCRQT-GDFTFECNCLPGFEGSTCERNIDDCPNHRCQNGGVCVDGVNTYN 283 Query: 404 CACPVTYTGKNC 439 C CP +TG+ C Sbjct: 284 CRCPPQWTGQFC 295 Score = 62.9 bits (146), Expect = 7e-10 Identities = 28/73 (38%), Positives = 34/73 (46%), Gaps = 1/73 (1%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLC-GPGKCMNTADSYK 403 C N C N G C + +GY C C GF G NC + C C G C + Y Sbjct: 761 CLSNPCQNGGTCDNLV--NGYRCTCKKGFKGYNCQVNIDECASNPCLNQGTCFDDISGYT 818 Query: 404 CACPVTYTGKNCE 442 C C + YTGKNC+ Sbjct: 819 CHCVLPYTGKNCQ 831 Score = 62.9 bits (146), Expect = 7e-10 Identities = 27/77 (35%), Positives = 40/77 (51%), Gaps = 1/77 (1%) Frame = +2 Query: 215 NCFTCAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLC-GPGKCMNTA 391 N C + C N G C + + + + CLC GF G+ C C C G C++ Sbjct: 987 NINECTESSCFNGGTCVDGI--NSFSCLCPVGFTGSFCLHEINECSSHPCLNEGTCVDGL 1044 Query: 392 DSYKCACPVTYTGKNCE 442 +Y+C+CP+ YTGKNC+ Sbjct: 1045 GTYRCSCPLGYTGKNCQ 1061 Score = 60.9 bits (141), Expect = 3e-09 Identities = 26/73 (35%), Positives = 38/73 (52%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLCGPGKCMNTADSYKC 406 C + CLN+G C + + +GY C C PG G NC+ + C C G CM+ + Y C Sbjct: 611 CYSSPCLNDGRCIDLV--NGYQCNCQPGTSGVNCEINFDDCASNPCIHGICMDGINRYSC 668 Query: 407 ACPVTYTGKNCEV 445 C +TG+ C + Sbjct: 669 VCSPGFTGQRCNI 681 Score = 58.8 bits (136), Expect = 1e-08 Identities = 27/71 (38%), Positives = 35/71 (49%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLCGPGKCMNTADSYKC 406 C+ CLN C + +GY C CA GF G C+ ++C P C G+C + DSY C Sbjct: 536 CSSTPCLNGAKCIDH--PNGYECQCATGFTGVLCEENIDNCDPDPCHHGQCQDGIDSYTC 593 Query: 407 ACPVTYTGKNC 439 C Y G C Sbjct: 594 ICNPGYMGAIC 604 Score = 57.6 bits (133), Expect = 3e-08 Identities = 31/95 (32%), Positives = 42/95 (44%), Gaps = 2/95 (2%) Frame = +2 Query: 203 ENVQNCFTCAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLCGPGK-C 379 E+V C PN C N G C A GY C+C G+ G++C + C C PG C Sbjct: 297 EDVDECLL-QPNACQNGGTC--ANRNGGYGCVCVNGWSGDDCSENIDDCAFASCTPGSTC 353 Query: 380 MNTADSYKCACPVTYTGKNCEVKQ-LIEYPAFTGS 481 ++ S+ C CP G C + I P G+ Sbjct: 354 IDRVASFSCMCPEGKAGLLCHLDDACISNPCHKGA 388 Score = 57.6 bits (133), Expect = 3e-08 Identities = 23/74 (31%), Positives = 40/74 (54%), Gaps = 1/74 (1%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLC-GPGKCMNTADSYK 403 C + C N+ C + + G+ CLC PGF G +C+ C+ C G+C++ + ++ Sbjct: 460 CHSDPCQNDATCLDKIG--GFTCLCMPGFKGVHCELEINECQSNPCVNNGQCVDKVNRFQ 517 Query: 404 CACPVTYTGKNCEV 445 C CP +TG C++ Sbjct: 518 CLCPPGFTGPVCQI 531 Score = 57.2 bits (132), Expect = 3e-08 Identities = 27/73 (36%), Positives = 37/73 (50%), Gaps = 1/73 (1%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLCGPG-KCMNTADSYK 403 C N C+NNG C + + + CLC PGF G C + C C G KC++ + Y+ Sbjct: 498 CQSNPCVNNGQCVDKVNR--FQCLCPPGFTGPVCQIDIDDCSSTPCLNGAKCIDHPNGYE 555 Query: 404 CACPVTYTGKNCE 442 C C +TG CE Sbjct: 556 CQCATGFTGVLCE 568 Score = 57.2 bits (132), Expect = 3e-08 Identities = 28/83 (33%), Positives = 45/83 (54%), Gaps = 1/83 (1%) Frame = +2 Query: 200 KENVQNCFTCAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNC-DRIGESCRPGLCGPGK 376 +EN+ NC P+ C ++G CQ+ + Y C+C PG+ G C D+I E G+ Sbjct: 568 EENIDNC---DPDPC-HHGQCQDGIDS--YTCICNPGYMGAICSDQIDECYSSPCLNDGR 621 Query: 377 CMNTADSYKCACPVTYTGKNCEV 445 C++ + Y+C C +G NCE+ Sbjct: 622 CIDLVNGYQCNCQPGTSGVNCEI 644 Score = 57.2 bits (132), Expect = 3e-08 Identities = 26/83 (31%), Positives = 39/83 (46%), Gaps = 3/83 (3%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLC-GPGKCMNTADSYK 403 C C N G C + + + Y C C GF G +C+ C C G C++ +S+ Sbjct: 953 CLSEPCKNGGTCSDYV--NSYTCKCQAGFDGVHCENNINECTESSCFNGGTCVDGINSFS 1010 Query: 404 CACPVTYTGKNC--EVKQLIEYP 466 C CPV +TG C E+ + +P Sbjct: 1011 CLCPVGFTGSFCLHEINECSSHP 1033 Score = 56.0 bits (129), Expect = 8e-08 Identities = 35/99 (35%), Positives = 44/99 (44%), Gaps = 6/99 (6%) Frame = +2 Query: 203 ENVQNCFTCAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCD-RIGESC---RPGLCGP 370 E Q+ C N C N G C C CA GF G +C C RP L G Sbjct: 60 EYCQHRDPCEKNRCQNGGTCVAQAMLGKATCRCASGFTGEDCQYSTSHPCFVSRPCLNG- 118 Query: 371 GKC-MNTADSYKCACPVTYTGKNCE-VKQLIEYPAFTGS 481 G C M + D+Y+C C V +TGK C+ + +P GS Sbjct: 119 GTCHMLSRDTYECTCQVGFTGKECQWTDACLSHPCANGS 157 Score = 56.0 bits (129), Expect = 8e-08 Identities = 23/69 (33%), Positives = 36/69 (52%), Gaps = 1/69 (1%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLC-GPGKCMNTADSYK 403 C C+N+G+C T+ Y+C C PGF G +C+ + C C G CM+ +++ Sbjct: 877 CISKPCMNHGLCHN--TQGSYMCECPPGFSGMDCEEDIDDCLANPCQNGGSCMDGVNTFS 934 Query: 404 CACPVTYTG 430 C C +TG Sbjct: 935 CLCLPGFTG 943 Score = 55.2 bits (127), Expect = 1e-07 Identities = 26/88 (29%), Positives = 44/88 (50%), Gaps = 3/88 (3%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLCGPG-KCMNTADSYK 403 CA N C++ G+C + + Y C+C+PGF G C+ + C C G C+N + ++ Sbjct: 649 CASNPCIH-GICMDGINR--YSCVCSPGFTGQRCNIDIDECASNPCRKGATCINGVNGFR 705 Query: 404 CACPVTYTGKNC--EVKQLIEYPAFTGS 481 C CP +C +V + + P G+ Sbjct: 706 CICPEGPHHPSCYSQVNECLSNPCIHGN 733 Score = 54.0 bits (124), Expect = 3e-07 Identities = 25/74 (33%), Positives = 34/74 (45%), Gaps = 2/74 (2%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCR-PGLCGPG-KCMNTADSY 400 C + C N C + + C C GF G C+ C PG C G C+N SY Sbjct: 148 CLSHPCANGSTCTTVANQ--FSCKCLTGFTGQKCETDVNECDIPGHCQHGGTCLNLPGSY 205 Query: 401 KCACPVTYTGKNCE 442 +C CP +TG+ C+ Sbjct: 206 QCQCPQGFTGQYCD 219 Score = 53.6 bits (123), Expect = 4e-07 Identities = 27/74 (36%), Positives = 36/74 (48%), Gaps = 1/74 (1%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLC-GPGKCMNTADSYK 403 C N C++ G C L+ GY CLC G+ G NC+ C C G C N + Y+ Sbjct: 724 CLSNPCIH-GNCTGGLS--GYKCLCDAGWVGINCEVDKNECLSNPCQNGGTCDNLVNGYR 780 Query: 404 CACPVTYTGKNCEV 445 C C + G NC+V Sbjct: 781 CTCKKGFKGYNCQV 794 Score = 53.6 bits (123), Expect = 4e-07 Identities = 26/80 (32%), Positives = 36/80 (45%), Gaps = 3/80 (3%) Frame = +2 Query: 215 NCFTCAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLC-GPGKCMNTA 391 N CA N CLN G C + ++ GY C C + G NC + C P C C + Sbjct: 795 NIDECASNPCLNQGTCFDDIS--GYTCHCVLPYTGKNCQTVLAPCSPNPCENAAVCKESP 852 Query: 392 --DSYKCACPVTYTGKNCEV 445 +SY C C + G+ C + Sbjct: 853 NFESYTCLCAPGWQGQRCTI 872 Score = 52.8 bits (121), Expect = 7e-07 Identities = 27/87 (31%), Positives = 37/87 (42%), Gaps = 3/87 (3%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLC-GPGKCMNTADSYK 403 C N C N G C + + + CLC PGF G+ C C G C + +SY Sbjct: 915 CLANPCQNGGSCMDGVNT--FSCLCLPGFTGDKYQTDMNECLSEPCKNGGTCSDYVNSYT 972 Query: 404 CACPVTYTGKNCE--VKQLIEYPAFTG 478 C C + G +CE + + E F G Sbjct: 973 CKCQAGFDGVHCENNINECTESSCFNG 999 Score = 52.4 bits (120), Expect = 1e-06 Identities = 22/64 (34%), Positives = 34/64 (53%), Gaps = 1/64 (1%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLC-GPGKCMNTADSYK 403 CA N C + C + + GY C C PG+ G NC+ + C+ C G C++ + +K Sbjct: 1153 CASNPCQHGATCSDFIG--GYRCECVPGYQGVNCEYEVDECQNQPCQNGGTCIDLVNHFK 1210 Query: 404 CACP 415 C+CP Sbjct: 1211 CSCP 1214 Score = 52.0 bits (119), Expect = 1e-06 Identities = 24/74 (32%), Positives = 33/74 (44%), Gaps = 1/74 (1%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLC-GPGKCMNTADSYK 403 C+ + CLN G C + L Y C C G+ G NC + C C G C+ + Sbjct: 1029 CSSHPCLNEGTCVDGLGT--YRCSCPLGYTGKNCQTLVNLCSRSPCKNKGTCVQKKAESQ 1086 Query: 404 CACPVTYTGKNCEV 445 C CP + G C+V Sbjct: 1087 CLCPSGWAGAYCDV 1100 Score = 51.2 bits (117), Expect = 2e-06 Identities = 23/77 (29%), Positives = 32/77 (41%), Gaps = 4/77 (5%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLCGP----GKCMNTAD 394 C N C +C Y+C C G+ G +C + C P GKC+NT Sbjct: 379 CISNPCHKGALCDTNPLNGQYICTCPQGYKGADCTEDVDECAMANSNPCEHAGKCVNTDG 438 Query: 395 SYKCACPVTYTGKNCEV 445 ++ C C Y G CE+ Sbjct: 439 AFHCECLKGYAGPRCEM 455 Score = 50.8 bits (116), Expect = 3e-06 Identities = 36/98 (36%), Positives = 47/98 (47%), Gaps = 15/98 (15%) Frame = +2 Query: 212 QNCFT----CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESC-----RPG-- 358 +NC T C+ + C N G C + E CLC G+ G CD SC R G Sbjct: 1058 KNCQTLVNLCSRSPCKNKGTCVQKKAESQ--CLCPSGWAGAYCDVPNVSCDIAASRRGVL 1115 Query: 359 ---LCG-PGKCMNTADSYKCACPVTYTGKNCEVKQLIE 460 LC G C+N +++ C CP+ YTG CE +QL E Sbjct: 1116 VEHLCQHSGVCINAGNTHYCQCPLGYTGSYCE-EQLDE 1152 Score = 48.8 bits (111), Expect = 1e-05 Identities = 24/70 (34%), Positives = 33/70 (47%), Gaps = 1/70 (1%) Frame = +2 Query: 236 NLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLCGPGK-CMNTADSYKCAC 412 +LC ++GVC A H C C G+ G+ C+ + C C G C + Y+C C Sbjct: 1118 HLCQHSGVCINAGNTH--YCQCPLGYTGSYCEEQLDECASNPCQHGATCSDFIGGYRCEC 1175 Query: 413 PVTYTGKNCE 442 Y G NCE Sbjct: 1176 VPGYQGVNCE 1185 Score = 48.0 bits (109), Expect = 2e-05 Identities = 23/73 (31%), Positives = 29/73 (39%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLCGPGKCMNTADSYKC 406 CA N C C + +G+ C+C G +C C C G C YKC Sbjct: 686 CASNPCRKGATCINGV--NGFRCICPEGPHHPSCYSQVNECLSNPCIHGNCTGGLSGYKC 743 Query: 407 ACPVTYTGKNCEV 445 C + G NCEV Sbjct: 744 LCDAGWVGINCEV 756 Score = 47.6 bits (108), Expect = 3e-05 Identities = 24/72 (33%), Positives = 30/72 (41%), Gaps = 2/72 (2%) Frame = +2 Query: 233 PNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLC-GPGKCMNTAD-SYKC 406 P C + G C Y C C GF G CD + C P C G C T D +++C Sbjct: 189 PGHCQHGGTCLNL--PGSYQCQCPQGFTGQYCDSLYVPCAPSPCVNGGTCRQTGDFTFEC 246 Query: 407 ACPVTYTGKNCE 442 C + G CE Sbjct: 247 NCLPGFEGSTCE 258 Score = 46.0 bits (104), Expect = 8e-05 Identities = 24/79 (30%), Positives = 35/79 (44%), Gaps = 3/79 (3%) Frame = +2 Query: 212 QNCFTCAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESC--RPGLC-GPGKCM 382 +N C + C N GVC + + + Y C C P + G C + C +P C G C Sbjct: 259 RNIDDCPNHRCQNGGVCVDGV--NTYNCRCPPQWTGQFCTEDVDECLLQPNACQNGGTCA 316 Query: 383 NTADSYKCACPVTYTGKNC 439 N Y C C ++G +C Sbjct: 317 NRNGGYGCVCVNGWSGDDC 335 Score = 43.6 bits (98), Expect = 4e-04 Identities = 21/83 (25%), Positives = 34/83 (40%), Gaps = 1/83 (1%) Frame = +2 Query: 203 ENVQNCFTCAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLC-GPGKC 379 E+V C N C + G C T+ + C C G+ G C+ C C C Sbjct: 414 EDVDECAMANSNPCEHAGKCVN--TDGAFHCECLKGYAGPRCEMDINECHSDPCQNDATC 471 Query: 380 MNTADSYKCACPVTYTGKNCEVK 448 ++ + C C + G +CE++ Sbjct: 472 LDKIGGFTCLCMPGFKGVHCELE 494 >AL596222-1|CAH70182.1| 2471|Homo sapiens Notch homolog 2 (Drosophila) protein. Length = 2471 Score = 70.9 bits (166), Expect = 3e-12 Identities = 34/82 (41%), Positives = 43/82 (52%), Gaps = 5/82 (6%) Frame = +2 Query: 212 QNCFT----CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLC-GPGK 376 +NC T C+PN C N VC+E+ Y CLCAPG+ G C + C C G Sbjct: 828 KNCQTVLAPCSPNPCENAAVCKESPNFESYTCLCAPGWQGQRCTIDIDECISKPCMNHGL 887 Query: 377 CMNTADSYKCACPVTYTGKNCE 442 C NT SY C CP ++G +CE Sbjct: 888 CHNTQGSYMCECPPGFSGMDCE 909 Score = 63.7 bits (148), Expect = 4e-10 Identities = 26/72 (36%), Positives = 41/72 (56%), Gaps = 1/72 (1%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLC-GPGKCMNTADSYK 403 CAP+ C+N G C++ + + C C PGF G+ C+R + C C G C++ ++Y Sbjct: 225 CAPSPCVNGGTCRQT-GDFTFECNCLPGFEGSTCERNIDDCPNHRCQNGGVCVDGVNTYN 283 Query: 404 CACPVTYTGKNC 439 C CP +TG+ C Sbjct: 284 CRCPPQWTGQFC 295 Score = 62.9 bits (146), Expect = 7e-10 Identities = 28/73 (38%), Positives = 34/73 (46%), Gaps = 1/73 (1%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLC-GPGKCMNTADSYK 403 C N C N G C + +GY C C GF G NC + C C G C + Y Sbjct: 761 CLSNPCQNGGTCDNLV--NGYRCTCKKGFKGYNCQVNIDECASNPCLNQGTCFDDISGYT 818 Query: 404 CACPVTYTGKNCE 442 C C + YTGKNC+ Sbjct: 819 CHCVLPYTGKNCQ 831 Score = 62.9 bits (146), Expect = 7e-10 Identities = 27/77 (35%), Positives = 40/77 (51%), Gaps = 1/77 (1%) Frame = +2 Query: 215 NCFTCAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLC-GPGKCMNTA 391 N C + C N G C + + + + CLC GF G+ C C C G C++ Sbjct: 987 NINECTESSCFNGGTCVDGI--NSFSCLCPVGFTGSFCLHEINECSSHPCLNEGTCVDGL 1044 Query: 392 DSYKCACPVTYTGKNCE 442 +Y+C+CP+ YTGKNC+ Sbjct: 1045 GTYRCSCPLGYTGKNCQ 1061 Score = 60.9 bits (141), Expect = 3e-09 Identities = 26/73 (35%), Positives = 38/73 (52%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLCGPGKCMNTADSYKC 406 C + CLN+G C + + +GY C C PG G NC+ + C C G CM+ + Y C Sbjct: 611 CYSSPCLNDGRCIDLV--NGYQCNCQPGTSGVNCEINFDDCASNPCIHGICMDGINRYSC 668 Query: 407 ACPVTYTGKNCEV 445 C +TG+ C + Sbjct: 669 VCSPGFTGQRCNI 681 Score = 60.1 bits (139), Expect = 5e-09 Identities = 24/73 (32%), Positives = 38/73 (52%), Gaps = 1/73 (1%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLC-GPGKCMNTADSYK 403 C C+N+G+C T+ Y+C C PGF G +C+ + C C G CM+ +++ Sbjct: 877 CISKPCMNHGLCHN--TQGSYMCECPPGFSGMDCEEDIDDCLANPCQNGGSCMDGVNTFS 934 Query: 404 CACPVTYTGKNCE 442 C C +TG C+ Sbjct: 935 CLCLPGFTGDKCQ 947 Score = 59.7 bits (138), Expect = 6e-09 Identities = 29/84 (34%), Positives = 41/84 (48%), Gaps = 3/84 (3%) Frame = +2 Query: 200 KENVQNCFTCAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLC---GP 370 +EN+ +C P+ CLN G C + + GY C C PGF G C+ C C G Sbjct: 1223 EENIDDCAR-GPH-CLNGGQCMDRIG--GYSCRCLPGFAGERCEGDINECLSNPCSSEGS 1278 Query: 371 GKCMNTADSYKCACPVTYTGKNCE 442 C+ + Y C C +TG++CE Sbjct: 1279 LDCIQLTNDYLCVCRSAFTGRHCE 1302 Score = 58.8 bits (136), Expect = 1e-08 Identities = 27/71 (38%), Positives = 35/71 (49%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLCGPGKCMNTADSYKC 406 C+ CLN C + +GY C CA GF G C+ ++C P C G+C + DSY C Sbjct: 536 CSSTPCLNGAKCIDH--PNGYECQCATGFTGVLCEENIDNCDPDPCHHGQCQDGIDSYTC 593 Query: 407 ACPVTYTGKNC 439 C Y G C Sbjct: 594 ICNPGYMGAIC 604 Score = 57.6 bits (133), Expect = 3e-08 Identities = 31/95 (32%), Positives = 42/95 (44%), Gaps = 2/95 (2%) Frame = +2 Query: 203 ENVQNCFTCAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLCGPGK-C 379 E+V C PN C N G C A GY C+C G+ G++C + C C PG C Sbjct: 297 EDVDECLL-QPNACQNGGTC--ANRNGGYGCVCVNGWSGDDCSENIDDCAFASCTPGSTC 353 Query: 380 MNTADSYKCACPVTYTGKNCEVKQ-LIEYPAFTGS 481 ++ S+ C CP G C + I P G+ Sbjct: 354 IDRVASFSCMCPEGKAGLLCHLDDACISNPCHKGA 388 Score = 57.6 bits (133), Expect = 3e-08 Identities = 23/74 (31%), Positives = 40/74 (54%), Gaps = 1/74 (1%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLC-GPGKCMNTADSYK 403 C + C N+ C + + G+ CLC PGF G +C+ C+ C G+C++ + ++ Sbjct: 460 CHSDPCQNDATCLDKIG--GFTCLCMPGFKGVHCELEINECQSNPCVNNGQCVDKVNRFQ 517 Query: 404 CACPVTYTGKNCEV 445 C CP +TG C++ Sbjct: 518 CLCPPGFTGPVCQI 531 Score = 57.2 bits (132), Expect = 3e-08 Identities = 27/73 (36%), Positives = 37/73 (50%), Gaps = 1/73 (1%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLCGPG-KCMNTADSYK 403 C N C+NNG C + + + CLC PGF G C + C C G KC++ + Y+ Sbjct: 498 CQSNPCVNNGQCVDKVNR--FQCLCPPGFTGPVCQIDIDDCSSTPCLNGAKCIDHPNGYE 555 Query: 404 CACPVTYTGKNCE 442 C C +TG CE Sbjct: 556 CQCATGFTGVLCE 568 Score = 57.2 bits (132), Expect = 3e-08 Identities = 28/83 (33%), Positives = 45/83 (54%), Gaps = 1/83 (1%) Frame = +2 Query: 200 KENVQNCFTCAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNC-DRIGESCRPGLCGPGK 376 +EN+ NC P+ C ++G CQ+ + Y C+C PG+ G C D+I E G+ Sbjct: 568 EENIDNC---DPDPC-HHGQCQDGIDS--YTCICNPGYMGAICSDQIDECYSSPCLNDGR 621 Query: 377 CMNTADSYKCACPVTYTGKNCEV 445 C++ + Y+C C +G NCE+ Sbjct: 622 CIDLVNGYQCNCQPGTSGVNCEI 644 Score = 57.2 bits (132), Expect = 3e-08 Identities = 28/87 (32%), Positives = 38/87 (43%), Gaps = 3/87 (3%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLC-GPGKCMNTADSYK 403 C N C N G C + + + CLC PGF G+ C C C G C + +SY Sbjct: 915 CLANPCQNGGSCMDGVNT--FSCLCLPGFTGDKCQTDMNECLSEPCKNGGTCSDYVNSYT 972 Query: 404 CACPVTYTGKNCE--VKQLIEYPAFTG 478 C C + G +CE + + E F G Sbjct: 973 CKCQAGFDGVHCENNINECTESSCFNG 999 Score = 57.2 bits (132), Expect = 3e-08 Identities = 26/83 (31%), Positives = 39/83 (46%), Gaps = 3/83 (3%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLC-GPGKCMNTADSYK 403 C C N G C + + + Y C C GF G +C+ C C G C++ +S+ Sbjct: 953 CLSEPCKNGGTCSDYV--NSYTCKCQAGFDGVHCENNINECTESSCFNGGTCVDGINSFS 1010 Query: 404 CACPVTYTGKNC--EVKQLIEYP 466 C CPV +TG C E+ + +P Sbjct: 1011 CLCPVGFTGSFCLHEINECSSHP 1033 Score = 56.0 bits (129), Expect = 8e-08 Identities = 35/99 (35%), Positives = 44/99 (44%), Gaps = 6/99 (6%) Frame = +2 Query: 203 ENVQNCFTCAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCD-RIGESC---RPGLCGP 370 E Q+ C N C N G C C CA GF G +C C RP L G Sbjct: 60 EYCQHRDPCEKNRCQNGGTCVAQAMLGKATCRCASGFTGEDCQYSTSHPCFVSRPCLNG- 118 Query: 371 GKC-MNTADSYKCACPVTYTGKNCE-VKQLIEYPAFTGS 481 G C M + D+Y+C C V +TGK C+ + +P GS Sbjct: 119 GTCHMLSRDTYECTCQVGFTGKECQWTDACLSHPCANGS 157 Score = 55.6 bits (128), Expect = 1e-07 Identities = 25/73 (34%), Positives = 37/73 (50%), Gaps = 1/73 (1%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLC-GPGKCMNTADSYK 403 CA N C + C + + GY C C PG+ G NC+ + C+ C G C++ + +K Sbjct: 1153 CASNPCQHGATCSDFIG--GYRCECVPGYQGVNCEYEVDECQNQPCQNGGTCIDLVNHFK 1210 Query: 404 CACPVTYTGKNCE 442 C+CP G CE Sbjct: 1211 CSCPPGTRGLLCE 1223 Score = 55.2 bits (127), Expect = 1e-07 Identities = 26/88 (29%), Positives = 44/88 (50%), Gaps = 3/88 (3%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLCGPG-KCMNTADSYK 403 CA N C++ G+C + + Y C+C+PGF G C+ + C C G C+N + ++ Sbjct: 649 CASNPCIH-GICMDGINR--YSCVCSPGFTGQRCNIDIDECASNPCRKGATCINGVNGFR 705 Query: 404 CACPVTYTGKNC--EVKQLIEYPAFTGS 481 C CP +C +V + + P G+ Sbjct: 706 CICPEGPHHPSCYSQVNECLSNPCIHGN 733 Score = 54.0 bits (124), Expect = 3e-07 Identities = 25/74 (33%), Positives = 34/74 (45%), Gaps = 2/74 (2%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCR-PGLCGPG-KCMNTADSY 400 C + C N C + + C C GF G C+ C PG C G C+N SY Sbjct: 148 CLSHPCANGSTCTTVANQ--FSCKCLTGFTGQKCETDVNECDIPGHCQHGGTCLNLPGSY 205 Query: 401 KCACPVTYTGKNCE 442 +C CP +TG+ C+ Sbjct: 206 QCQCPQGFTGQYCD 219 Score = 53.6 bits (123), Expect = 4e-07 Identities = 27/74 (36%), Positives = 36/74 (48%), Gaps = 1/74 (1%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLC-GPGKCMNTADSYK 403 C N C++ G C L+ GY CLC G+ G NC+ C C G C N + Y+ Sbjct: 724 CLSNPCIH-GNCTGGLS--GYKCLCDAGWVGINCEVDKNECLSNPCQNGGTCDNLVNGYR 780 Query: 404 CACPVTYTGKNCEV 445 C C + G NC+V Sbjct: 781 CTCKKGFKGYNCQV 794 Score = 53.6 bits (123), Expect = 4e-07 Identities = 26/80 (32%), Positives = 36/80 (45%), Gaps = 3/80 (3%) Frame = +2 Query: 215 NCFTCAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLC-GPGKCMNTA 391 N CA N CLN G C + ++ GY C C + G NC + C P C C + Sbjct: 795 NIDECASNPCLNQGTCFDDIS--GYTCHCVLPYTGKNCQTVLAPCSPNPCENAAVCKESP 852 Query: 392 --DSYKCACPVTYTGKNCEV 445 +SY C C + G+ C + Sbjct: 853 NFESYTCLCAPGWQGQRCTI 872 Score = 52.0 bits (119), Expect = 1e-06 Identities = 24/74 (32%), Positives = 33/74 (44%), Gaps = 1/74 (1%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLC-GPGKCMNTADSYK 403 C+ + CLN G C + L Y C C G+ G NC + C C G C+ + Sbjct: 1029 CSSHPCLNEGTCVDGLGT--YRCSCPLGYTGKNCQTLVNLCSRSPCKNKGTCVQKKAESQ 1086 Query: 404 CACPVTYTGKNCEV 445 C CP + G C+V Sbjct: 1087 CLCPSGWAGAYCDV 1100 Score = 51.2 bits (117), Expect = 2e-06 Identities = 23/77 (29%), Positives = 32/77 (41%), Gaps = 4/77 (5%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLCGP----GKCMNTAD 394 C N C +C Y+C C G+ G +C + C P GKC+NT Sbjct: 379 CISNPCHKGALCDTNPLNGQYICTCPQGYKGADCTEDVDECAMANSNPCEHAGKCVNTDG 438 Query: 395 SYKCACPVTYTGKNCEV 445 ++ C C Y G CE+ Sbjct: 439 AFHCECLKGYAGPRCEM 455 Score = 50.8 bits (116), Expect = 3e-06 Identities = 36/98 (36%), Positives = 47/98 (47%), Gaps = 15/98 (15%) Frame = +2 Query: 212 QNCFT----CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESC-----RPG-- 358 +NC T C+ + C N G C + E CLC G+ G CD SC R G Sbjct: 1058 KNCQTLVNLCSRSPCKNKGTCVQKKAESQ--CLCPSGWAGAYCDVPNVSCDIAASRRGVL 1115 Query: 359 ---LCG-PGKCMNTADSYKCACPVTYTGKNCEVKQLIE 460 LC G C+N +++ C CP+ YTG CE +QL E Sbjct: 1116 VEHLCQHSGVCINAGNTHYCQCPLGYTGSYCE-EQLDE 1152 Score = 48.0 bits (109), Expect = 2e-05 Identities = 23/73 (31%), Positives = 29/73 (39%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLCGPGKCMNTADSYKC 406 CA N C C + +G+ C+C G +C C C G C YKC Sbjct: 686 CASNPCRKGATCINGV--NGFRCICPEGPHHPSCYSQVNECLSNPCIHGNCTGGLSGYKC 743 Query: 407 ACPVTYTGKNCEV 445 C + G NCEV Sbjct: 744 LCDAGWVGINCEV 756 Score = 47.6 bits (108), Expect = 3e-05 Identities = 24/72 (33%), Positives = 30/72 (41%), Gaps = 2/72 (2%) Frame = +2 Query: 233 PNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLC-GPGKCMNTAD-SYKC 406 P C + G C Y C C GF G CD + C P C G C T D +++C Sbjct: 189 PGHCQHGGTCLNL--PGSYQCQCPQGFTGQYCDSLYVPCAPSPCVNGGTCRQTGDFTFEC 246 Query: 407 ACPVTYTGKNCE 442 C + G CE Sbjct: 247 NCLPGFEGSTCE 258 Score = 47.2 bits (107), Expect = 4e-05 Identities = 24/74 (32%), Positives = 32/74 (43%), Gaps = 2/74 (2%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCR--PGLCGPGKCMNTADSY 400 C C N G C + L H + C C PG G C+ + C P G+CM+ Y Sbjct: 1191 CQNQPCQNGGTCID-LVNH-FKCSCPPGTRGLLCEENIDDCARGPHCLNGGQCMDRIGGY 1248 Query: 401 KCACPVTYTGKNCE 442 C C + G+ CE Sbjct: 1249 SCRCLPGFAGERCE 1262 Score = 46.0 bits (104), Expect = 8e-05 Identities = 24/79 (30%), Positives = 35/79 (44%), Gaps = 3/79 (3%) Frame = +2 Query: 212 QNCFTCAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESC--RPGLC-GPGKCM 382 +N C + C N GVC + + + Y C C P + G C + C +P C G C Sbjct: 259 RNIDDCPNHRCQNGGVCVDGV--NTYNCRCPPQWTGQFCTEDVDECLLQPNACQNGGTCA 316 Query: 383 NTADSYKCACPVTYTGKNC 439 N Y C C ++G +C Sbjct: 317 NRNGGYGCVCVNGWSGDDC 335 Score = 44.0 bits (99), Expect = 3e-04 Identities = 21/76 (27%), Positives = 32/76 (42%), Gaps = 4/76 (5%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLC-GPGKC---MNTAD 394 C N C + G + Y+C+C F G +C+ + C C G C N D Sbjct: 1268 CLSNPCSSEGSLDCIQLTNDYLCVCRSAFTGRHCETFVDVCPQMPCLNGGTCAVASNMPD 1327 Query: 395 SYKCACPVTYTGKNCE 442 + C CP ++G C+ Sbjct: 1328 GFICRCPPGFSGARCQ 1343 Score = 43.6 bits (98), Expect = 4e-04 Identities = 21/83 (25%), Positives = 34/83 (40%), Gaps = 1/83 (1%) Frame = +2 Query: 203 ENVQNCFTCAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLC-GPGKC 379 E+V C N C + G C T+ + C C G+ G C+ C C C Sbjct: 414 EDVDECAMANSNPCEHAGKCVN--TDGAFHCECLKGYAGPRCEMDINECHSDPCQNDATC 471 Query: 380 MNTADSYKCACPVTYTGKNCEVK 448 ++ + C C + G +CE++ Sbjct: 472 LDKIGGFTCLCMPGFKGVHCELE 494 Score = 35.1 bits (77), Expect = 0.16 Identities = 19/62 (30%), Positives = 24/62 (38%), Gaps = 2/62 (3%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCD--RIGESCRPGLCGPGKCMNTADSY 400 CA + C + G C Y C CAP F G+ C+ S P C C + A Sbjct: 1378 CASSPCQHGGSCHPQRQPPYYSCQCAPPFSGSRCELYTAPPSTPPATCLSQYCADKARDG 1437 Query: 401 KC 406 C Sbjct: 1438 VC 1439 >AL512503-1|CAH72483.1| 2471|Homo sapiens Notch homolog 2 (Drosophila) protein. Length = 2471 Score = 70.9 bits (166), Expect = 3e-12 Identities = 34/82 (41%), Positives = 43/82 (52%), Gaps = 5/82 (6%) Frame = +2 Query: 212 QNCFT----CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLC-GPGK 376 +NC T C+PN C N VC+E+ Y CLCAPG+ G C + C C G Sbjct: 828 KNCQTVLAPCSPNPCENAAVCKESPNFESYTCLCAPGWQGQRCTIDIDECISKPCMNHGL 887 Query: 377 CMNTADSYKCACPVTYTGKNCE 442 C NT SY C CP ++G +CE Sbjct: 888 CHNTQGSYMCECPPGFSGMDCE 909 Score = 63.7 bits (148), Expect = 4e-10 Identities = 26/72 (36%), Positives = 41/72 (56%), Gaps = 1/72 (1%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLC-GPGKCMNTADSYK 403 CAP+ C+N G C++ + + C C PGF G+ C+R + C C G C++ ++Y Sbjct: 225 CAPSPCVNGGTCRQT-GDFTFECNCLPGFEGSTCERNIDDCPNHRCQNGGVCVDGVNTYN 283 Query: 404 CACPVTYTGKNC 439 C CP +TG+ C Sbjct: 284 CRCPPQWTGQFC 295 Score = 62.9 bits (146), Expect = 7e-10 Identities = 28/73 (38%), Positives = 34/73 (46%), Gaps = 1/73 (1%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLC-GPGKCMNTADSYK 403 C N C N G C + +GY C C GF G NC + C C G C + Y Sbjct: 761 CLSNPCQNGGTCDNLV--NGYRCTCKKGFKGYNCQVNIDECASNPCLNQGTCFDDISGYT 818 Query: 404 CACPVTYTGKNCE 442 C C + YTGKNC+ Sbjct: 819 CHCVLPYTGKNCQ 831 Score = 62.9 bits (146), Expect = 7e-10 Identities = 27/77 (35%), Positives = 40/77 (51%), Gaps = 1/77 (1%) Frame = +2 Query: 215 NCFTCAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLC-GPGKCMNTA 391 N C + C N G C + + + + CLC GF G+ C C C G C++ Sbjct: 987 NINECTESSCFNGGTCVDGI--NSFSCLCPVGFTGSFCLHEINECSSHPCLNEGTCVDGL 1044 Query: 392 DSYKCACPVTYTGKNCE 442 +Y+C+CP+ YTGKNC+ Sbjct: 1045 GTYRCSCPLGYTGKNCQ 1061 Score = 60.9 bits (141), Expect = 3e-09 Identities = 26/73 (35%), Positives = 38/73 (52%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLCGPGKCMNTADSYKC 406 C + CLN+G C + + +GY C C PG G NC+ + C C G CM+ + Y C Sbjct: 611 CYSSPCLNDGRCIDLV--NGYQCNCQPGTSGVNCEINFDDCASNPCIHGICMDGINRYSC 668 Query: 407 ACPVTYTGKNCEV 445 C +TG+ C + Sbjct: 669 VCSPGFTGQRCNI 681 Score = 60.1 bits (139), Expect = 5e-09 Identities = 24/73 (32%), Positives = 38/73 (52%), Gaps = 1/73 (1%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLC-GPGKCMNTADSYK 403 C C+N+G+C T+ Y+C C PGF G +C+ + C C G CM+ +++ Sbjct: 877 CISKPCMNHGLCHN--TQGSYMCECPPGFSGMDCEEDIDDCLANPCQNGGSCMDGVNTFS 934 Query: 404 CACPVTYTGKNCE 442 C C +TG C+ Sbjct: 935 CLCLPGFTGDKCQ 947 Score = 59.7 bits (138), Expect = 6e-09 Identities = 29/84 (34%), Positives = 41/84 (48%), Gaps = 3/84 (3%) Frame = +2 Query: 200 KENVQNCFTCAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLC---GP 370 +EN+ +C P+ CLN G C + + GY C C PGF G C+ C C G Sbjct: 1223 EENIDDCAR-GPH-CLNGGQCMDRIG--GYSCRCLPGFAGERCEGDINECLSNPCSSEGS 1278 Query: 371 GKCMNTADSYKCACPVTYTGKNCE 442 C+ + Y C C +TG++CE Sbjct: 1279 LDCIQLTNDYLCVCRSAFTGRHCE 1302 Score = 58.8 bits (136), Expect = 1e-08 Identities = 27/71 (38%), Positives = 35/71 (49%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLCGPGKCMNTADSYKC 406 C+ CLN C + +GY C CA GF G C+ ++C P C G+C + DSY C Sbjct: 536 CSSTPCLNGAKCIDH--PNGYECQCATGFTGVLCEENIDNCDPDPCHHGQCQDGIDSYTC 593 Query: 407 ACPVTYTGKNC 439 C Y G C Sbjct: 594 ICNPGYMGAIC 604 Score = 57.6 bits (133), Expect = 3e-08 Identities = 31/95 (32%), Positives = 42/95 (44%), Gaps = 2/95 (2%) Frame = +2 Query: 203 ENVQNCFTCAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLCGPGK-C 379 E+V C PN C N G C A GY C+C G+ G++C + C C PG C Sbjct: 297 EDVDECLL-QPNACQNGGTC--ANRNGGYGCVCVNGWSGDDCSENIDDCAFASCTPGSTC 353 Query: 380 MNTADSYKCACPVTYTGKNCEVKQ-LIEYPAFTGS 481 ++ S+ C CP G C + I P G+ Sbjct: 354 IDRVASFSCMCPEGKAGLLCHLDDACISNPCHKGA 388 Score = 57.6 bits (133), Expect = 3e-08 Identities = 23/74 (31%), Positives = 40/74 (54%), Gaps = 1/74 (1%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLC-GPGKCMNTADSYK 403 C + C N+ C + + G+ CLC PGF G +C+ C+ C G+C++ + ++ Sbjct: 460 CHSDPCQNDATCLDKIG--GFTCLCMPGFKGVHCELEINECQSNPCVNNGQCVDKVNRFQ 517 Query: 404 CACPVTYTGKNCEV 445 C CP +TG C++ Sbjct: 518 CLCPPGFTGPVCQI 531 Score = 57.2 bits (132), Expect = 3e-08 Identities = 27/73 (36%), Positives = 37/73 (50%), Gaps = 1/73 (1%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLCGPG-KCMNTADSYK 403 C N C+NNG C + + + CLC PGF G C + C C G KC++ + Y+ Sbjct: 498 CQSNPCVNNGQCVDKVNR--FQCLCPPGFTGPVCQIDIDDCSSTPCLNGAKCIDHPNGYE 555 Query: 404 CACPVTYTGKNCE 442 C C +TG CE Sbjct: 556 CQCATGFTGVLCE 568 Score = 57.2 bits (132), Expect = 3e-08 Identities = 28/83 (33%), Positives = 45/83 (54%), Gaps = 1/83 (1%) Frame = +2 Query: 200 KENVQNCFTCAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNC-DRIGESCRPGLCGPGK 376 +EN+ NC P+ C ++G CQ+ + Y C+C PG+ G C D+I E G+ Sbjct: 568 EENIDNC---DPDPC-HHGQCQDGIDS--YTCICNPGYMGAICSDQIDECYSSPCLNDGR 621 Query: 377 CMNTADSYKCACPVTYTGKNCEV 445 C++ + Y+C C +G NCE+ Sbjct: 622 CIDLVNGYQCNCQPGTSGVNCEI 644 Score = 57.2 bits (132), Expect = 3e-08 Identities = 28/87 (32%), Positives = 38/87 (43%), Gaps = 3/87 (3%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLC-GPGKCMNTADSYK 403 C N C N G C + + + CLC PGF G+ C C C G C + +SY Sbjct: 915 CLANPCQNGGSCMDGVNT--FSCLCLPGFTGDKCQTDMNECLSEPCKNGGTCSDYVNSYT 972 Query: 404 CACPVTYTGKNCE--VKQLIEYPAFTG 478 C C + G +CE + + E F G Sbjct: 973 CKCQAGFDGVHCENNINECTESSCFNG 999 Score = 57.2 bits (132), Expect = 3e-08 Identities = 26/83 (31%), Positives = 39/83 (46%), Gaps = 3/83 (3%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLC-GPGKCMNTADSYK 403 C C N G C + + + Y C C GF G +C+ C C G C++ +S+ Sbjct: 953 CLSEPCKNGGTCSDYV--NSYTCKCQAGFDGVHCENNINECTESSCFNGGTCVDGINSFS 1010 Query: 404 CACPVTYTGKNC--EVKQLIEYP 466 C CPV +TG C E+ + +P Sbjct: 1011 CLCPVGFTGSFCLHEINECSSHP 1033 Score = 56.0 bits (129), Expect = 8e-08 Identities = 35/99 (35%), Positives = 44/99 (44%), Gaps = 6/99 (6%) Frame = +2 Query: 203 ENVQNCFTCAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCD-RIGESC---RPGLCGP 370 E Q+ C N C N G C C CA GF G +C C RP L G Sbjct: 60 EYCQHRDPCEKNRCQNGGTCVAQAMLGKATCRCASGFTGEDCQYSTSHPCFVSRPCLNG- 118 Query: 371 GKC-MNTADSYKCACPVTYTGKNCE-VKQLIEYPAFTGS 481 G C M + D+Y+C C V +TGK C+ + +P GS Sbjct: 119 GTCHMLSRDTYECTCQVGFTGKECQWTDACLSHPCANGS 157 Score = 55.6 bits (128), Expect = 1e-07 Identities = 25/73 (34%), Positives = 37/73 (50%), Gaps = 1/73 (1%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLC-GPGKCMNTADSYK 403 CA N C + C + + GY C C PG+ G NC+ + C+ C G C++ + +K Sbjct: 1153 CASNPCQHGATCSDFIG--GYRCECVPGYQGVNCEYEVDECQNQPCQNGGTCIDLVNHFK 1210 Query: 404 CACPVTYTGKNCE 442 C+CP G CE Sbjct: 1211 CSCPPGTRGLLCE 1223 Score = 55.2 bits (127), Expect = 1e-07 Identities = 26/88 (29%), Positives = 44/88 (50%), Gaps = 3/88 (3%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLCGPG-KCMNTADSYK 403 CA N C++ G+C + + Y C+C+PGF G C+ + C C G C+N + ++ Sbjct: 649 CASNPCIH-GICMDGINR--YSCVCSPGFTGQRCNIDIDECASNPCRKGATCINGVNGFR 705 Query: 404 CACPVTYTGKNC--EVKQLIEYPAFTGS 481 C CP +C +V + + P G+ Sbjct: 706 CICPEGPHHPSCYSQVNECLSNPCIHGN 733 Score = 54.0 bits (124), Expect = 3e-07 Identities = 25/74 (33%), Positives = 34/74 (45%), Gaps = 2/74 (2%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCR-PGLCGPG-KCMNTADSY 400 C + C N C + + C C GF G C+ C PG C G C+N SY Sbjct: 148 CLSHPCANGSTCTTVANQ--FSCKCLTGFTGQKCETDVNECDIPGHCQHGGTCLNLPGSY 205 Query: 401 KCACPVTYTGKNCE 442 +C CP +TG+ C+ Sbjct: 206 QCQCPQGFTGQYCD 219 Score = 53.6 bits (123), Expect = 4e-07 Identities = 27/74 (36%), Positives = 36/74 (48%), Gaps = 1/74 (1%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLC-GPGKCMNTADSYK 403 C N C++ G C L+ GY CLC G+ G NC+ C C G C N + Y+ Sbjct: 724 CLSNPCIH-GNCTGGLS--GYKCLCDAGWVGINCEVDKNECLSNPCQNGGTCDNLVNGYR 780 Query: 404 CACPVTYTGKNCEV 445 C C + G NC+V Sbjct: 781 CTCKKGFKGYNCQV 794 Score = 53.6 bits (123), Expect = 4e-07 Identities = 26/80 (32%), Positives = 36/80 (45%), Gaps = 3/80 (3%) Frame = +2 Query: 215 NCFTCAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLC-GPGKCMNTA 391 N CA N CLN G C + ++ GY C C + G NC + C P C C + Sbjct: 795 NIDECASNPCLNQGTCFDDIS--GYTCHCVLPYTGKNCQTVLAPCSPNPCENAAVCKESP 852 Query: 392 --DSYKCACPVTYTGKNCEV 445 +SY C C + G+ C + Sbjct: 853 NFESYTCLCAPGWQGQRCTI 872 Score = 52.0 bits (119), Expect = 1e-06 Identities = 24/74 (32%), Positives = 33/74 (44%), Gaps = 1/74 (1%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLC-GPGKCMNTADSYK 403 C+ + CLN G C + L Y C C G+ G NC + C C G C+ + Sbjct: 1029 CSSHPCLNEGTCVDGLGT--YRCSCPLGYTGKNCQTLVNLCSRSPCKNKGTCVQKKAESQ 1086 Query: 404 CACPVTYTGKNCEV 445 C CP + G C+V Sbjct: 1087 CLCPSGWAGAYCDV 1100 Score = 51.2 bits (117), Expect = 2e-06 Identities = 23/77 (29%), Positives = 32/77 (41%), Gaps = 4/77 (5%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLCGP----GKCMNTAD 394 C N C +C Y+C C G+ G +C + C P GKC+NT Sbjct: 379 CISNPCHKGALCDTNPLNGQYICTCPQGYKGADCTEDVDECAMANSNPCEHAGKCVNTDG 438 Query: 395 SYKCACPVTYTGKNCEV 445 ++ C C Y G CE+ Sbjct: 439 AFHCECLKGYAGPRCEM 455 Score = 50.8 bits (116), Expect = 3e-06 Identities = 36/98 (36%), Positives = 47/98 (47%), Gaps = 15/98 (15%) Frame = +2 Query: 212 QNCFT----CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESC-----RPG-- 358 +NC T C+ + C N G C + E CLC G+ G CD SC R G Sbjct: 1058 KNCQTLVNLCSRSPCKNKGTCVQKKAESQ--CLCPSGWAGAYCDVPNVSCDIAASRRGVL 1115 Query: 359 ---LCG-PGKCMNTADSYKCACPVTYTGKNCEVKQLIE 460 LC G C+N +++ C CP+ YTG CE +QL E Sbjct: 1116 VEHLCQHSGVCINAGNTHYCQCPLGYTGSYCE-EQLDE 1152 Score = 48.0 bits (109), Expect = 2e-05 Identities = 23/73 (31%), Positives = 29/73 (39%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLCGPGKCMNTADSYKC 406 CA N C C + +G+ C+C G +C C C G C YKC Sbjct: 686 CASNPCRKGATCINGV--NGFRCICPEGPHHPSCYSQVNECLSNPCIHGNCTGGLSGYKC 743 Query: 407 ACPVTYTGKNCEV 445 C + G NCEV Sbjct: 744 LCDAGWVGINCEV 756 Score = 47.6 bits (108), Expect = 3e-05 Identities = 24/72 (33%), Positives = 30/72 (41%), Gaps = 2/72 (2%) Frame = +2 Query: 233 PNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLC-GPGKCMNTAD-SYKC 406 P C + G C Y C C GF G CD + C P C G C T D +++C Sbjct: 189 PGHCQHGGTCLNL--PGSYQCQCPQGFTGQYCDSLYVPCAPSPCVNGGTCRQTGDFTFEC 246 Query: 407 ACPVTYTGKNCE 442 C + G CE Sbjct: 247 NCLPGFEGSTCE 258 Score = 47.2 bits (107), Expect = 4e-05 Identities = 24/74 (32%), Positives = 32/74 (43%), Gaps = 2/74 (2%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCR--PGLCGPGKCMNTADSY 400 C C N G C + L H + C C PG G C+ + C P G+CM+ Y Sbjct: 1191 CQNQPCQNGGTCID-LVNH-FKCSCPPGTRGLLCEENIDDCARGPHCLNGGQCMDRIGGY 1248 Query: 401 KCACPVTYTGKNCE 442 C C + G+ CE Sbjct: 1249 SCRCLPGFAGERCE 1262 Score = 46.0 bits (104), Expect = 8e-05 Identities = 24/79 (30%), Positives = 35/79 (44%), Gaps = 3/79 (3%) Frame = +2 Query: 212 QNCFTCAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESC--RPGLC-GPGKCM 382 +N C + C N GVC + + + Y C C P + G C + C +P C G C Sbjct: 259 RNIDDCPNHRCQNGGVCVDGV--NTYNCRCPPQWTGQFCTEDVDECLLQPNACQNGGTCA 316 Query: 383 NTADSYKCACPVTYTGKNC 439 N Y C C ++G +C Sbjct: 317 NRNGGYGCVCVNGWSGDDC 335 Score = 44.0 bits (99), Expect = 3e-04 Identities = 21/76 (27%), Positives = 32/76 (42%), Gaps = 4/76 (5%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLC-GPGKC---MNTAD 394 C N C + G + Y+C+C F G +C+ + C C G C N D Sbjct: 1268 CLSNPCSSEGSLDCIQLTNDYLCVCRSAFTGRHCETFVDVCPQMPCLNGGTCAVASNMPD 1327 Query: 395 SYKCACPVTYTGKNCE 442 + C CP ++G C+ Sbjct: 1328 GFICRCPPGFSGARCQ 1343 Score = 43.6 bits (98), Expect = 4e-04 Identities = 21/83 (25%), Positives = 34/83 (40%), Gaps = 1/83 (1%) Frame = +2 Query: 203 ENVQNCFTCAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLC-GPGKC 379 E+V C N C + G C T+ + C C G+ G C+ C C C Sbjct: 414 EDVDECAMANSNPCEHAGKCVN--TDGAFHCECLKGYAGPRCEMDINECHSDPCQNDATC 471 Query: 380 MNTADSYKCACPVTYTGKNCEVK 448 ++ + C C + G +CE++ Sbjct: 472 LDKIGGFTCLCMPGFKGVHCELE 494 Score = 35.1 bits (77), Expect = 0.16 Identities = 19/62 (30%), Positives = 24/62 (38%), Gaps = 2/62 (3%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCD--RIGESCRPGLCGPGKCMNTADSY 400 CA + C + G C Y C CAP F G+ C+ S P C C + A Sbjct: 1378 CASSPCQHGGSCHPQRQPPYYSCQCAPPFSGSRCELYTAPPSTPPATCLSQYCADKARDG 1437 Query: 401 KC 406 C Sbjct: 1438 VC 1439 >AL359752-4|CAI18974.1| 2471|Homo sapiens Notch homolog 2 (Drosophila) protein. Length = 2471 Score = 70.9 bits (166), Expect = 3e-12 Identities = 34/82 (41%), Positives = 43/82 (52%), Gaps = 5/82 (6%) Frame = +2 Query: 212 QNCFT----CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLC-GPGK 376 +NC T C+PN C N VC+E+ Y CLCAPG+ G C + C C G Sbjct: 828 KNCQTVLAPCSPNPCENAAVCKESPNFESYTCLCAPGWQGQRCTIDIDECISKPCMNHGL 887 Query: 377 CMNTADSYKCACPVTYTGKNCE 442 C NT SY C CP ++G +CE Sbjct: 888 CHNTQGSYMCECPPGFSGMDCE 909 Score = 63.7 bits (148), Expect = 4e-10 Identities = 26/72 (36%), Positives = 41/72 (56%), Gaps = 1/72 (1%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLC-GPGKCMNTADSYK 403 CAP+ C+N G C++ + + C C PGF G+ C+R + C C G C++ ++Y Sbjct: 225 CAPSPCVNGGTCRQT-GDFTFECNCLPGFEGSTCERNIDDCPNHRCQNGGVCVDGVNTYN 283 Query: 404 CACPVTYTGKNC 439 C CP +TG+ C Sbjct: 284 CRCPPQWTGQFC 295 Score = 62.9 bits (146), Expect = 7e-10 Identities = 28/73 (38%), Positives = 34/73 (46%), Gaps = 1/73 (1%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLC-GPGKCMNTADSYK 403 C N C N G C + +GY C C GF G NC + C C G C + Y Sbjct: 761 CLSNPCQNGGTCDNLV--NGYRCTCKKGFKGYNCQVNIDECASNPCLNQGTCFDDISGYT 818 Query: 404 CACPVTYTGKNCE 442 C C + YTGKNC+ Sbjct: 819 CHCVLPYTGKNCQ 831 Score = 62.9 bits (146), Expect = 7e-10 Identities = 27/77 (35%), Positives = 40/77 (51%), Gaps = 1/77 (1%) Frame = +2 Query: 215 NCFTCAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLC-GPGKCMNTA 391 N C + C N G C + + + + CLC GF G+ C C C G C++ Sbjct: 987 NINECTESSCFNGGTCVDGI--NSFSCLCPVGFTGSFCLHEINECSSHPCLNEGTCVDGL 1044 Query: 392 DSYKCACPVTYTGKNCE 442 +Y+C+CP+ YTGKNC+ Sbjct: 1045 GTYRCSCPLGYTGKNCQ 1061 Score = 60.9 bits (141), Expect = 3e-09 Identities = 26/73 (35%), Positives = 38/73 (52%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLCGPGKCMNTADSYKC 406 C + CLN+G C + + +GY C C PG G NC+ + C C G CM+ + Y C Sbjct: 611 CYSSPCLNDGRCIDLV--NGYQCNCQPGTSGVNCEINFDDCASNPCIHGICMDGINRYSC 668 Query: 407 ACPVTYTGKNCEV 445 C +TG+ C + Sbjct: 669 VCSPGFTGQRCNI 681 Score = 60.1 bits (139), Expect = 5e-09 Identities = 24/73 (32%), Positives = 38/73 (52%), Gaps = 1/73 (1%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLC-GPGKCMNTADSYK 403 C C+N+G+C T+ Y+C C PGF G +C+ + C C G CM+ +++ Sbjct: 877 CISKPCMNHGLCHN--TQGSYMCECPPGFSGMDCEEDIDDCLANPCQNGGSCMDGVNTFS 934 Query: 404 CACPVTYTGKNCE 442 C C +TG C+ Sbjct: 935 CLCLPGFTGDKCQ 947 Score = 59.7 bits (138), Expect = 6e-09 Identities = 29/84 (34%), Positives = 41/84 (48%), Gaps = 3/84 (3%) Frame = +2 Query: 200 KENVQNCFTCAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLC---GP 370 +EN+ +C P+ CLN G C + + GY C C PGF G C+ C C G Sbjct: 1223 EENIDDCAR-GPH-CLNGGQCMDRIG--GYSCRCLPGFAGERCEGDINECLSNPCSSEGS 1278 Query: 371 GKCMNTADSYKCACPVTYTGKNCE 442 C+ + Y C C +TG++CE Sbjct: 1279 LDCIQLTNDYLCVCRSAFTGRHCE 1302 Score = 58.8 bits (136), Expect = 1e-08 Identities = 27/71 (38%), Positives = 35/71 (49%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLCGPGKCMNTADSYKC 406 C+ CLN C + +GY C CA GF G C+ ++C P C G+C + DSY C Sbjct: 536 CSSTPCLNGAKCIDH--PNGYECQCATGFTGVLCEENIDNCDPDPCHHGQCQDGIDSYTC 593 Query: 407 ACPVTYTGKNC 439 C Y G C Sbjct: 594 ICNPGYMGAIC 604 Score = 57.6 bits (133), Expect = 3e-08 Identities = 31/95 (32%), Positives = 42/95 (44%), Gaps = 2/95 (2%) Frame = +2 Query: 203 ENVQNCFTCAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLCGPGK-C 379 E+V C PN C N G C A GY C+C G+ G++C + C C PG C Sbjct: 297 EDVDECLL-QPNACQNGGTC--ANRNGGYGCVCVNGWSGDDCSENIDDCAFASCTPGSTC 353 Query: 380 MNTADSYKCACPVTYTGKNCEVKQ-LIEYPAFTGS 481 ++ S+ C CP G C + I P G+ Sbjct: 354 IDRVASFSCMCPEGKAGLLCHLDDACISNPCHKGA 388 Score = 57.6 bits (133), Expect = 3e-08 Identities = 23/74 (31%), Positives = 40/74 (54%), Gaps = 1/74 (1%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLC-GPGKCMNTADSYK 403 C + C N+ C + + G+ CLC PGF G +C+ C+ C G+C++ + ++ Sbjct: 460 CHSDPCQNDATCLDKIG--GFTCLCMPGFKGVHCELEINECQSNPCVNNGQCVDKVNRFQ 517 Query: 404 CACPVTYTGKNCEV 445 C CP +TG C++ Sbjct: 518 CLCPPGFTGPVCQI 531 Score = 57.2 bits (132), Expect = 3e-08 Identities = 27/73 (36%), Positives = 37/73 (50%), Gaps = 1/73 (1%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLCGPG-KCMNTADSYK 403 C N C+NNG C + + + CLC PGF G C + C C G KC++ + Y+ Sbjct: 498 CQSNPCVNNGQCVDKVNR--FQCLCPPGFTGPVCQIDIDDCSSTPCLNGAKCIDHPNGYE 555 Query: 404 CACPVTYTGKNCE 442 C C +TG CE Sbjct: 556 CQCATGFTGVLCE 568 Score = 57.2 bits (132), Expect = 3e-08 Identities = 28/83 (33%), Positives = 45/83 (54%), Gaps = 1/83 (1%) Frame = +2 Query: 200 KENVQNCFTCAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNC-DRIGESCRPGLCGPGK 376 +EN+ NC P+ C ++G CQ+ + Y C+C PG+ G C D+I E G+ Sbjct: 568 EENIDNC---DPDPC-HHGQCQDGIDS--YTCICNPGYMGAICSDQIDECYSSPCLNDGR 621 Query: 377 CMNTADSYKCACPVTYTGKNCEV 445 C++ + Y+C C +G NCE+ Sbjct: 622 CIDLVNGYQCNCQPGTSGVNCEI 644 Score = 57.2 bits (132), Expect = 3e-08 Identities = 28/87 (32%), Positives = 38/87 (43%), Gaps = 3/87 (3%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLC-GPGKCMNTADSYK 403 C N C N G C + + + CLC PGF G+ C C C G C + +SY Sbjct: 915 CLANPCQNGGSCMDGVNT--FSCLCLPGFTGDKCQTDMNECLSEPCKNGGTCSDYVNSYT 972 Query: 404 CACPVTYTGKNCE--VKQLIEYPAFTG 478 C C + G +CE + + E F G Sbjct: 973 CKCQAGFDGVHCENNINECTESSCFNG 999 Score = 57.2 bits (132), Expect = 3e-08 Identities = 26/83 (31%), Positives = 39/83 (46%), Gaps = 3/83 (3%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLC-GPGKCMNTADSYK 403 C C N G C + + + Y C C GF G +C+ C C G C++ +S+ Sbjct: 953 CLSEPCKNGGTCSDYV--NSYTCKCQAGFDGVHCENNINECTESSCFNGGTCVDGINSFS 1010 Query: 404 CACPVTYTGKNC--EVKQLIEYP 466 C CPV +TG C E+ + +P Sbjct: 1011 CLCPVGFTGSFCLHEINECSSHP 1033 Score = 56.0 bits (129), Expect = 8e-08 Identities = 35/99 (35%), Positives = 44/99 (44%), Gaps = 6/99 (6%) Frame = +2 Query: 203 ENVQNCFTCAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCD-RIGESC---RPGLCGP 370 E Q+ C N C N G C C CA GF G +C C RP L G Sbjct: 60 EYCQHRDPCEKNRCQNGGTCVAQAMLGKATCRCASGFTGEDCQYSTSHPCFVSRPCLNG- 118 Query: 371 GKC-MNTADSYKCACPVTYTGKNCE-VKQLIEYPAFTGS 481 G C M + D+Y+C C V +TGK C+ + +P GS Sbjct: 119 GTCHMLSRDTYECTCQVGFTGKECQWTDACLSHPCANGS 157 Score = 55.6 bits (128), Expect = 1e-07 Identities = 25/73 (34%), Positives = 37/73 (50%), Gaps = 1/73 (1%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLC-GPGKCMNTADSYK 403 CA N C + C + + GY C C PG+ G NC+ + C+ C G C++ + +K Sbjct: 1153 CASNPCQHGATCSDFIG--GYRCECVPGYQGVNCEYEVDECQNQPCQNGGTCIDLVNHFK 1210 Query: 404 CACPVTYTGKNCE 442 C+CP G CE Sbjct: 1211 CSCPPGTRGLLCE 1223 Score = 55.2 bits (127), Expect = 1e-07 Identities = 26/88 (29%), Positives = 44/88 (50%), Gaps = 3/88 (3%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLCGPG-KCMNTADSYK 403 CA N C++ G+C + + Y C+C+PGF G C+ + C C G C+N + ++ Sbjct: 649 CASNPCIH-GICMDGINR--YSCVCSPGFTGQRCNIDIDECASNPCRKGATCINGVNGFR 705 Query: 404 CACPVTYTGKNC--EVKQLIEYPAFTGS 481 C CP +C +V + + P G+ Sbjct: 706 CICPEGPHHPSCYSQVNECLSNPCIHGN 733 Score = 54.0 bits (124), Expect = 3e-07 Identities = 25/74 (33%), Positives = 34/74 (45%), Gaps = 2/74 (2%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCR-PGLCGPG-KCMNTADSY 400 C + C N C + + C C GF G C+ C PG C G C+N SY Sbjct: 148 CLSHPCANGSTCTTVANQ--FSCKCLTGFTGQKCETDVNECDIPGHCQHGGTCLNLPGSY 205 Query: 401 KCACPVTYTGKNCE 442 +C CP +TG+ C+ Sbjct: 206 QCQCPQGFTGQYCD 219 Score = 53.6 bits (123), Expect = 4e-07 Identities = 27/74 (36%), Positives = 36/74 (48%), Gaps = 1/74 (1%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLC-GPGKCMNTADSYK 403 C N C++ G C L+ GY CLC G+ G NC+ C C G C N + Y+ Sbjct: 724 CLSNPCIH-GNCTGGLS--GYKCLCDAGWVGINCEVDKNECLSNPCQNGGTCDNLVNGYR 780 Query: 404 CACPVTYTGKNCEV 445 C C + G NC+V Sbjct: 781 CTCKKGFKGYNCQV 794 Score = 53.6 bits (123), Expect = 4e-07 Identities = 26/80 (32%), Positives = 36/80 (45%), Gaps = 3/80 (3%) Frame = +2 Query: 215 NCFTCAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLC-GPGKCMNTA 391 N CA N CLN G C + ++ GY C C + G NC + C P C C + Sbjct: 795 NIDECASNPCLNQGTCFDDIS--GYTCHCVLPYTGKNCQTVLAPCSPNPCENAAVCKESP 852 Query: 392 --DSYKCACPVTYTGKNCEV 445 +SY C C + G+ C + Sbjct: 853 NFESYTCLCAPGWQGQRCTI 872 Score = 52.0 bits (119), Expect = 1e-06 Identities = 24/74 (32%), Positives = 33/74 (44%), Gaps = 1/74 (1%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLC-GPGKCMNTADSYK 403 C+ + CLN G C + L Y C C G+ G NC + C C G C+ + Sbjct: 1029 CSSHPCLNEGTCVDGLGT--YRCSCPLGYTGKNCQTLVNLCSRSPCKNKGTCVQKKAESQ 1086 Query: 404 CACPVTYTGKNCEV 445 C CP + G C+V Sbjct: 1087 CLCPSGWAGAYCDV 1100 Score = 51.2 bits (117), Expect = 2e-06 Identities = 23/77 (29%), Positives = 32/77 (41%), Gaps = 4/77 (5%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLCGP----GKCMNTAD 394 C N C +C Y+C C G+ G +C + C P GKC+NT Sbjct: 379 CISNPCHKGALCDTNPLNGQYICTCPQGYKGADCTEDVDECAMANSNPCEHAGKCVNTDG 438 Query: 395 SYKCACPVTYTGKNCEV 445 ++ C C Y G CE+ Sbjct: 439 AFHCECLKGYAGPRCEM 455 Score = 50.8 bits (116), Expect = 3e-06 Identities = 36/98 (36%), Positives = 47/98 (47%), Gaps = 15/98 (15%) Frame = +2 Query: 212 QNCFT----CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESC-----RPG-- 358 +NC T C+ + C N G C + E CLC G+ G CD SC R G Sbjct: 1058 KNCQTLVNLCSRSPCKNKGTCVQKKAESQ--CLCPSGWAGAYCDVPNVSCDIAASRRGVL 1115 Query: 359 ---LCG-PGKCMNTADSYKCACPVTYTGKNCEVKQLIE 460 LC G C+N +++ C CP+ YTG CE +QL E Sbjct: 1116 VEHLCQHSGVCINAGNTHYCQCPLGYTGSYCE-EQLDE 1152 Score = 48.0 bits (109), Expect = 2e-05 Identities = 23/73 (31%), Positives = 29/73 (39%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLCGPGKCMNTADSYKC 406 CA N C C + +G+ C+C G +C C C G C YKC Sbjct: 686 CASNPCRKGATCINGV--NGFRCICPEGPHHPSCYSQVNECLSNPCIHGNCTGGLSGYKC 743 Query: 407 ACPVTYTGKNCEV 445 C + G NCEV Sbjct: 744 LCDAGWVGINCEV 756 Score = 47.6 bits (108), Expect = 3e-05 Identities = 24/72 (33%), Positives = 30/72 (41%), Gaps = 2/72 (2%) Frame = +2 Query: 233 PNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLC-GPGKCMNTAD-SYKC 406 P C + G C Y C C GF G CD + C P C G C T D +++C Sbjct: 189 PGHCQHGGTCLNL--PGSYQCQCPQGFTGQYCDSLYVPCAPSPCVNGGTCRQTGDFTFEC 246 Query: 407 ACPVTYTGKNCE 442 C + G CE Sbjct: 247 NCLPGFEGSTCE 258 Score = 47.2 bits (107), Expect = 4e-05 Identities = 24/74 (32%), Positives = 32/74 (43%), Gaps = 2/74 (2%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCR--PGLCGPGKCMNTADSY 400 C C N G C + L H + C C PG G C+ + C P G+CM+ Y Sbjct: 1191 CQNQPCQNGGTCID-LVNH-FKCSCPPGTRGLLCEENIDDCARGPHCLNGGQCMDRIGGY 1248 Query: 401 KCACPVTYTGKNCE 442 C C + G+ CE Sbjct: 1249 SCRCLPGFAGERCE 1262 Score = 46.0 bits (104), Expect = 8e-05 Identities = 24/79 (30%), Positives = 35/79 (44%), Gaps = 3/79 (3%) Frame = +2 Query: 212 QNCFTCAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESC--RPGLC-GPGKCM 382 +N C + C N GVC + + + Y C C P + G C + C +P C G C Sbjct: 259 RNIDDCPNHRCQNGGVCVDGV--NTYNCRCPPQWTGQFCTEDVDECLLQPNACQNGGTCA 316 Query: 383 NTADSYKCACPVTYTGKNC 439 N Y C C ++G +C Sbjct: 317 NRNGGYGCVCVNGWSGDDC 335 Score = 44.0 bits (99), Expect = 3e-04 Identities = 21/76 (27%), Positives = 32/76 (42%), Gaps = 4/76 (5%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLC-GPGKC---MNTAD 394 C N C + G + Y+C+C F G +C+ + C C G C N D Sbjct: 1268 CLSNPCSSEGSLDCIQLTNDYLCVCRSAFTGRHCETFVDVCPQMPCLNGGTCAVASNMPD 1327 Query: 395 SYKCACPVTYTGKNCE 442 + C CP ++G C+ Sbjct: 1328 GFICRCPPGFSGARCQ 1343 Score = 43.6 bits (98), Expect = 4e-04 Identities = 21/83 (25%), Positives = 34/83 (40%), Gaps = 1/83 (1%) Frame = +2 Query: 203 ENVQNCFTCAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLC-GPGKC 379 E+V C N C + G C T+ + C C G+ G C+ C C C Sbjct: 414 EDVDECAMANSNPCEHAGKCVN--TDGAFHCECLKGYAGPRCEMDINECHSDPCQNDATC 471 Query: 380 MNTADSYKCACPVTYTGKNCEVK 448 ++ + C C + G +CE++ Sbjct: 472 LDKIGGFTCLCMPGFKGVHCELE 494 Score = 35.1 bits (77), Expect = 0.16 Identities = 19/62 (30%), Positives = 24/62 (38%), Gaps = 2/62 (3%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCD--RIGESCRPGLCGPGKCMNTADSY 400 CA + C + G C Y C CAP F G+ C+ S P C C + A Sbjct: 1378 CASSPCQHGGSCHPQRQPPYYSCQCAPPFSGSRCELYTAPPSTPPATCLSQYCADKARDG 1437 Query: 401 KC 406 C Sbjct: 1438 VC 1439 >AF315356-1|AAG37073.1| 2471|Homo sapiens NOTCH2 protein protein. Length = 2471 Score = 70.9 bits (166), Expect = 3e-12 Identities = 34/82 (41%), Positives = 43/82 (52%), Gaps = 5/82 (6%) Frame = +2 Query: 212 QNCFT----CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLC-GPGK 376 +NC T C+PN C N VC+E+ Y CLCAPG+ G C + C C G Sbjct: 828 KNCQTVLAPCSPNPCENAAVCKESPNFESYTCLCAPGWQGQRCTIDIDECISKPCMNHGL 887 Query: 377 CMNTADSYKCACPVTYTGKNCE 442 C NT SY C CP ++G +CE Sbjct: 888 CHNTQGSYMCECPPGFSGMDCE 909 Score = 63.7 bits (148), Expect = 4e-10 Identities = 26/72 (36%), Positives = 41/72 (56%), Gaps = 1/72 (1%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLC-GPGKCMNTADSYK 403 CAP+ C+N G C++ + + C C PGF G+ C+R + C C G C++ ++Y Sbjct: 225 CAPSPCVNGGTCRQT-GDFTFECNCLPGFEGSTCERNIDDCPNHRCQNGGVCVDGVNTYN 283 Query: 404 CACPVTYTGKNC 439 C CP +TG+ C Sbjct: 284 CRCPPQWTGQFC 295 Score = 62.9 bits (146), Expect = 7e-10 Identities = 28/73 (38%), Positives = 34/73 (46%), Gaps = 1/73 (1%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLC-GPGKCMNTADSYK 403 C N C N G C + +GY C C GF G NC + C C G C + Y Sbjct: 761 CLSNPCQNGGTCDNLV--NGYRCTCKKGFKGYNCQVNIDECASNPCLNQGTCFDDISGYT 818 Query: 404 CACPVTYTGKNCE 442 C C + YTGKNC+ Sbjct: 819 CHCVLPYTGKNCQ 831 Score = 62.9 bits (146), Expect = 7e-10 Identities = 27/77 (35%), Positives = 40/77 (51%), Gaps = 1/77 (1%) Frame = +2 Query: 215 NCFTCAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLC-GPGKCMNTA 391 N C + C N G C + + + + CLC GF G+ C C C G C++ Sbjct: 987 NINECTESSCFNGGTCVDGI--NSFSCLCPVGFTGSFCLHEINECSSHPCLNEGTCVDGL 1044 Query: 392 DSYKCACPVTYTGKNCE 442 +Y+C+CP+ YTGKNC+ Sbjct: 1045 GTYRCSCPLGYTGKNCQ 1061 Score = 60.9 bits (141), Expect = 3e-09 Identities = 26/73 (35%), Positives = 38/73 (52%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLCGPGKCMNTADSYKC 406 C + CLN+G C + + +GY C C PG G NC+ + C C G CM+ + Y C Sbjct: 611 CYSSPCLNDGRCIDLV--NGYQCNCQPGTSGVNCEINFDDCASNPCIHGICMDGINRYSC 668 Query: 407 ACPVTYTGKNCEV 445 C +TG+ C + Sbjct: 669 VCSPGFTGQRCNI 681 Score = 60.1 bits (139), Expect = 5e-09 Identities = 24/73 (32%), Positives = 38/73 (52%), Gaps = 1/73 (1%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLC-GPGKCMNTADSYK 403 C C+N+G+C T+ Y+C C PGF G +C+ + C C G CM+ +++ Sbjct: 877 CISKPCMNHGLCHN--TQGSYMCECPPGFSGMDCEEDIDDCLANPCQNGGSCMDGVNTFS 934 Query: 404 CACPVTYTGKNCE 442 C C +TG C+ Sbjct: 935 CLCLPGFTGDKCQ 947 Score = 59.7 bits (138), Expect = 6e-09 Identities = 29/84 (34%), Positives = 41/84 (48%), Gaps = 3/84 (3%) Frame = +2 Query: 200 KENVQNCFTCAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLC---GP 370 +EN+ +C P+ CLN G C + + GY C C PGF G C+ C C G Sbjct: 1223 EENIDDCAR-GPH-CLNGGQCMDRIG--GYSCRCLPGFAGERCEGDINECLSNPCSSEGS 1278 Query: 371 GKCMNTADSYKCACPVTYTGKNCE 442 C+ + Y C C +TG++CE Sbjct: 1279 LDCIQLTNDYLCVCRSAFTGRHCE 1302 Score = 58.8 bits (136), Expect = 1e-08 Identities = 27/71 (38%), Positives = 35/71 (49%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLCGPGKCMNTADSYKC 406 C+ CLN C + +GY C CA GF G C+ ++C P C G+C + DSY C Sbjct: 536 CSSTPCLNGAKCIDH--PNGYECQCATGFTGVLCEENIDNCDPDPCHHGQCQDGIDSYTC 593 Query: 407 ACPVTYTGKNC 439 C Y G C Sbjct: 594 ICNPGYMGAIC 604 Score = 57.6 bits (133), Expect = 3e-08 Identities = 31/95 (32%), Positives = 42/95 (44%), Gaps = 2/95 (2%) Frame = +2 Query: 203 ENVQNCFTCAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLCGPGK-C 379 E+V C PN C N G C A GY C+C G+ G++C + C C PG C Sbjct: 297 EDVDECLL-QPNACQNGGTC--ANRNGGYGCVCVNGWSGDDCSENIDDCAFASCTPGSTC 353 Query: 380 MNTADSYKCACPVTYTGKNCEVKQ-LIEYPAFTGS 481 ++ S+ C CP G C + I P G+ Sbjct: 354 IDRVASFSCMCPEGKAGLLCHLDDACISNPCHKGA 388 Score = 57.6 bits (133), Expect = 3e-08 Identities = 23/74 (31%), Positives = 40/74 (54%), Gaps = 1/74 (1%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLC-GPGKCMNTADSYK 403 C + C N+ C + + G+ CLC PGF G +C+ C+ C G+C++ + ++ Sbjct: 460 CHSDPCQNDATCLDKIG--GFTCLCMPGFKGVHCELEINECQSNPCVNNGQCVDKVNRFQ 517 Query: 404 CACPVTYTGKNCEV 445 C CP +TG C++ Sbjct: 518 CLCPPGFTGPVCQI 531 Score = 57.2 bits (132), Expect = 3e-08 Identities = 27/73 (36%), Positives = 37/73 (50%), Gaps = 1/73 (1%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLCGPG-KCMNTADSYK 403 C N C+NNG C + + + CLC PGF G C + C C G KC++ + Y+ Sbjct: 498 CQSNPCVNNGQCVDKVNR--FQCLCPPGFTGPVCQIDIDDCSSTPCLNGAKCIDHPNGYE 555 Query: 404 CACPVTYTGKNCE 442 C C +TG CE Sbjct: 556 CQCATGFTGVLCE 568 Score = 57.2 bits (132), Expect = 3e-08 Identities = 28/83 (33%), Positives = 45/83 (54%), Gaps = 1/83 (1%) Frame = +2 Query: 200 KENVQNCFTCAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNC-DRIGESCRPGLCGPGK 376 +EN+ NC P+ C ++G CQ+ + Y C+C PG+ G C D+I E G+ Sbjct: 568 EENIDNC---DPDPC-HHGQCQDGIDS--YTCICNPGYMGAICSDQIDECYSSPCLNDGR 621 Query: 377 CMNTADSYKCACPVTYTGKNCEV 445 C++ + Y+C C +G NCE+ Sbjct: 622 CIDLVNGYQCNCQPGTSGVNCEI 644 Score = 57.2 bits (132), Expect = 3e-08 Identities = 28/87 (32%), Positives = 38/87 (43%), Gaps = 3/87 (3%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLC-GPGKCMNTADSYK 403 C N C N G C + + + CLC PGF G+ C C C G C + +SY Sbjct: 915 CLANPCQNGGSCMDGVNT--FSCLCLPGFTGDKCQTDMNECLSEPCKNGGTCSDYVNSYT 972 Query: 404 CACPVTYTGKNCE--VKQLIEYPAFTG 478 C C + G +CE + + E F G Sbjct: 973 CKCQAGFDGVHCENNINECTESSCFNG 999 Score = 57.2 bits (132), Expect = 3e-08 Identities = 26/83 (31%), Positives = 39/83 (46%), Gaps = 3/83 (3%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLC-GPGKCMNTADSYK 403 C C N G C + + + Y C C GF G +C+ C C G C++ +S+ Sbjct: 953 CLSEPCKNGGTCSDYV--NSYTCKCQAGFDGVHCENNINECTESSCFNGGTCVDGINSFS 1010 Query: 404 CACPVTYTGKNC--EVKQLIEYP 466 C CPV +TG C E+ + +P Sbjct: 1011 CLCPVGFTGSFCLHEINECSSHP 1033 Score = 56.0 bits (129), Expect = 8e-08 Identities = 35/99 (35%), Positives = 44/99 (44%), Gaps = 6/99 (6%) Frame = +2 Query: 203 ENVQNCFTCAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCD-RIGESC---RPGLCGP 370 E Q+ C N C N G C C CA GF G +C C RP L G Sbjct: 60 EYCQHRDPCEKNRCQNGGTCVAQAMLGKATCRCASGFTGEDCQYSTSHPCFVSRPCLNG- 118 Query: 371 GKC-MNTADSYKCACPVTYTGKNCE-VKQLIEYPAFTGS 481 G C M + D+Y+C C V +TGK C+ + +P GS Sbjct: 119 GTCHMLSRDTYECTCQVGFTGKECQWTDACLSHPCANGS 157 Score = 55.6 bits (128), Expect = 1e-07 Identities = 25/73 (34%), Positives = 37/73 (50%), Gaps = 1/73 (1%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLC-GPGKCMNTADSYK 403 CA N C + C + + GY C C PG+ G NC+ + C+ C G C++ + +K Sbjct: 1153 CASNPCQHGATCSDFIG--GYRCECVPGYQGVNCEYEVDECQNQPCQNGGTCIDLVNHFK 1210 Query: 404 CACPVTYTGKNCE 442 C+CP G CE Sbjct: 1211 CSCPPGTRGLLCE 1223 Score = 55.2 bits (127), Expect = 1e-07 Identities = 26/88 (29%), Positives = 44/88 (50%), Gaps = 3/88 (3%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLCGPG-KCMNTADSYK 403 CA N C++ G+C + + Y C+C+PGF G C+ + C C G C+N + ++ Sbjct: 649 CASNPCIH-GICMDGINR--YSCVCSPGFTGQRCNIDIDECASNPCRKGATCINGVNGFR 705 Query: 404 CACPVTYTGKNC--EVKQLIEYPAFTGS 481 C CP +C +V + + P G+ Sbjct: 706 CICPEGPHHPSCYSQVNECLSNPCIHGN 733 Score = 53.6 bits (123), Expect = 4e-07 Identities = 27/76 (35%), Positives = 34/76 (44%), Gaps = 1/76 (1%) Frame = +2 Query: 218 CFTCAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLCGPGK-CMNTAD 394 CF P CLN G C L+ Y C C GF G C ++C C G C A+ Sbjct: 109 CFVSRP--CLNGGTCH-MLSRDTYECTCQVGFTGKECQWT-DACLSHPCANGSTCTTVAN 164 Query: 395 SYKCACPVTYTGKNCE 442 + C C +TG+ CE Sbjct: 165 QFSCKCLTGFTGQKCE 180 Score = 53.6 bits (123), Expect = 4e-07 Identities = 27/74 (36%), Positives = 36/74 (48%), Gaps = 1/74 (1%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLC-GPGKCMNTADSYK 403 C N C++ G C L+ GY CLC G+ G NC+ C C G C N + Y+ Sbjct: 724 CLSNPCIH-GNCTGGLS--GYKCLCDAGWVGINCEVDKNECLSNPCQNGGTCDNLVNGYR 780 Query: 404 CACPVTYTGKNCEV 445 C C + G NC+V Sbjct: 781 CTCKKGFKGYNCQV 794 Score = 53.6 bits (123), Expect = 4e-07 Identities = 26/80 (32%), Positives = 36/80 (45%), Gaps = 3/80 (3%) Frame = +2 Query: 215 NCFTCAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLC-GPGKCMNTA 391 N CA N CLN G C + ++ GY C C + G NC + C P C C + Sbjct: 795 NIDECASNPCLNQGTCFDDIS--GYTCHCVLPYTGKNCQTVLAPCSPNPCENAAVCKESP 852 Query: 392 --DSYKCACPVTYTGKNCEV 445 +SY C C + G+ C + Sbjct: 853 NFESYTCLCAPGWQGQRCTI 872 Score = 52.0 bits (119), Expect = 1e-06 Identities = 24/74 (32%), Positives = 33/74 (44%), Gaps = 1/74 (1%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLC-GPGKCMNTADSYK 403 C+ + CLN G C + L Y C C G+ G NC + C C G C+ + Sbjct: 1029 CSSHPCLNEGTCVDGLGT--YRCSCPLGYTGKNCQTLVNLCSRSPCKNKGTCVQKKAESQ 1086 Query: 404 CACPVTYTGKNCEV 445 C CP + G C+V Sbjct: 1087 CLCPSGWAGAYCDV 1100 Score = 51.2 bits (117), Expect = 2e-06 Identities = 23/77 (29%), Positives = 32/77 (41%), Gaps = 4/77 (5%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLCGP----GKCMNTAD 394 C N C +C Y+C C G+ G +C + C P GKC+NT Sbjct: 379 CISNPCHKGALCDTNPLNGQYICTCPQGYKGADCTEDVDECAMANSNPCEHAGKCVNTDG 438 Query: 395 SYKCACPVTYTGKNCEV 445 ++ C C Y G CE+ Sbjct: 439 AFHCECLKGYAGPRCEM 455 Score = 50.8 bits (116), Expect = 3e-06 Identities = 36/98 (36%), Positives = 47/98 (47%), Gaps = 15/98 (15%) Frame = +2 Query: 212 QNCFT----CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESC-----RPG-- 358 +NC T C+ + C N G C + E CLC G+ G CD SC R G Sbjct: 1058 KNCQTLVNLCSRSPCKNKGTCVQKKAESQ--CLCPSGWAGAYCDVPNVSCDIAASRRGVL 1115 Query: 359 ---LCG-PGKCMNTADSYKCACPVTYTGKNCEVKQLIE 460 LC G C+N +++ C CP+ YTG CE +QL E Sbjct: 1116 VEHLCQHSGVCINAGNTHYCQCPLGYTGSYCE-EQLDE 1152 Score = 48.0 bits (109), Expect = 2e-05 Identities = 23/73 (31%), Positives = 29/73 (39%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLCGPGKCMNTADSYKC 406 CA N C C + +G+ C+C G +C C C G C YKC Sbjct: 686 CASNPCRKGATCINGV--NGFRCICPEGPHHPSCYSQVNECLSNPCIHGNCTGGLSGYKC 743 Query: 407 ACPVTYTGKNCEV 445 C + G NCEV Sbjct: 744 LCDAGWVGINCEV 756 Score = 47.6 bits (108), Expect = 3e-05 Identities = 24/72 (33%), Positives = 30/72 (41%), Gaps = 2/72 (2%) Frame = +2 Query: 233 PNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLC-GPGKCMNTAD-SYKC 406 P C + G C Y C C GF G CD + C P C G C T D +++C Sbjct: 189 PGHCQHGGTCLNL--PGSYQCQCLQGFTGQYCDSLYVPCAPSPCVNGGTCRQTGDFTFEC 246 Query: 407 ACPVTYTGKNCE 442 C + G CE Sbjct: 247 NCLPGFEGSTCE 258 Score = 47.2 bits (107), Expect = 4e-05 Identities = 24/74 (32%), Positives = 32/74 (43%), Gaps = 2/74 (2%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCR--PGLCGPGKCMNTADSY 400 C C N G C + L H + C C PG G C+ + C P G+CM+ Y Sbjct: 1191 CQNQPCQNGGTCID-LVNH-FKCSCPPGTRGLLCEENIDDCARGPHCLNGGQCMDRIGGY 1248 Query: 401 KCACPVTYTGKNCE 442 C C + G+ CE Sbjct: 1249 SCRCLPGFAGERCE 1262 Score = 46.0 bits (104), Expect = 8e-05 Identities = 24/79 (30%), Positives = 35/79 (44%), Gaps = 3/79 (3%) Frame = +2 Query: 212 QNCFTCAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESC--RPGLC-GPGKCM 382 +N C + C N GVC + + + Y C C P + G C + C +P C G C Sbjct: 259 RNIDDCPNHRCQNGGVCVDGV--NTYNCRCPPQWTGQFCTEDVDECLLQPNACQNGGTCA 316 Query: 383 NTADSYKCACPVTYTGKNC 439 N Y C C ++G +C Sbjct: 317 NRNGGYGCVCVNGWSGDDC 335 Score = 44.0 bits (99), Expect = 3e-04 Identities = 21/76 (27%), Positives = 32/76 (42%), Gaps = 4/76 (5%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLC-GPGKC---MNTAD 394 C N C + G + Y+C+C F G +C+ + C C G C N D Sbjct: 1268 CLSNPCSSEGSLDCIQLTNDYLCVCRSAFTGRHCETFVDVCPQMPCLNGGTCAVASNMPD 1327 Query: 395 SYKCACPVTYTGKNCE 442 + C CP ++G C+ Sbjct: 1328 GFICRCPPGFSGARCQ 1343 Score = 43.6 bits (98), Expect = 4e-04 Identities = 21/83 (25%), Positives = 34/83 (40%), Gaps = 1/83 (1%) Frame = +2 Query: 203 ENVQNCFTCAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLC-GPGKC 379 E+V C N C + G C T+ + C C G+ G C+ C C C Sbjct: 414 EDVDECAMANSNPCEHAGKCVN--TDGAFHCECLKGYAGPRCEMDINECHSDPCQNDATC 471 Query: 380 MNTADSYKCACPVTYTGKNCEVK 448 ++ + C C + G +CE++ Sbjct: 472 LDKIGGFTCLCMPGFKGVHCELE 494 Score = 35.1 bits (77), Expect = 0.16 Identities = 19/62 (30%), Positives = 24/62 (38%), Gaps = 2/62 (3%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCD--RIGESCRPGLCGPGKCMNTADSY 400 CA + C + G C Y C CAP F G+ C+ S P C C + A Sbjct: 1378 CASSPCQHGGSCHPQRQPPYYSCQCAPPFSGSRCELYTAPPSTPPATCLSQYCADKARDG 1437 Query: 401 KC 406 C Sbjct: 1438 VC 1439 >AF308601-1|AAA36377.2| 2471|Homo sapiens NOTCH 2 protein. Length = 2471 Score = 70.9 bits (166), Expect = 3e-12 Identities = 34/82 (41%), Positives = 43/82 (52%), Gaps = 5/82 (6%) Frame = +2 Query: 212 QNCFT----CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLC-GPGK 376 +NC T C+PN C N VC+E+ Y CLCAPG+ G C + C C G Sbjct: 828 KNCQTVLAPCSPNPCENAAVCKESPNFESYTCLCAPGWQGQRCTIDIDECISKPCMNHGL 887 Query: 377 CMNTADSYKCACPVTYTGKNCE 442 C NT SY C CP ++G +CE Sbjct: 888 CHNTQGSYMCECPPGFSGMDCE 909 Score = 63.7 bits (148), Expect = 4e-10 Identities = 26/72 (36%), Positives = 41/72 (56%), Gaps = 1/72 (1%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLC-GPGKCMNTADSYK 403 CAP+ C+N G C++ + + C C PGF G+ C+R + C C G C++ ++Y Sbjct: 225 CAPSPCVNGGTCRQT-GDFTFECNCLPGFEGSTCERNIDDCPNHRCQNGGVCVDGVNTYN 283 Query: 404 CACPVTYTGKNC 439 C CP +TG+ C Sbjct: 284 CRCPPQWTGQFC 295 Score = 62.9 bits (146), Expect = 7e-10 Identities = 28/73 (38%), Positives = 34/73 (46%), Gaps = 1/73 (1%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLC-GPGKCMNTADSYK 403 C N C N G C + +GY C C GF G NC + C C G C + Y Sbjct: 761 CLSNPCQNGGTCDNLV--NGYRCTCKKGFKGYNCQVNIDECASNPCLNQGTCFDDISGYT 818 Query: 404 CACPVTYTGKNCE 442 C C + YTGKNC+ Sbjct: 819 CHCVLPYTGKNCQ 831 Score = 62.9 bits (146), Expect = 7e-10 Identities = 27/77 (35%), Positives = 40/77 (51%), Gaps = 1/77 (1%) Frame = +2 Query: 215 NCFTCAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLC-GPGKCMNTA 391 N C + C N G C + + + + CLC GF G+ C C C G C++ Sbjct: 987 NINECTESSCFNGGTCVDGI--NSFSCLCPVGFTGSFCLHEINECSSHPCLNEGTCVDGL 1044 Query: 392 DSYKCACPVTYTGKNCE 442 +Y+C+CP+ YTGKNC+ Sbjct: 1045 GTYRCSCPLGYTGKNCQ 1061 Score = 60.9 bits (141), Expect = 3e-09 Identities = 26/73 (35%), Positives = 38/73 (52%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLCGPGKCMNTADSYKC 406 C + CLN+G C + + +GY C C PG G NC+ + C C G CM+ + Y C Sbjct: 611 CYSSPCLNDGRCIDLV--NGYQCNCQPGTSGVNCEINFDDCASNPCIHGICMDGINRYSC 668 Query: 407 ACPVTYTGKNCEV 445 C +TG+ C + Sbjct: 669 VCSPGFTGQRCNI 681 Score = 60.1 bits (139), Expect = 5e-09 Identities = 24/73 (32%), Positives = 38/73 (52%), Gaps = 1/73 (1%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLC-GPGKCMNTADSYK 403 C C+N+G+C T+ Y+C C PGF G +C+ + C C G CM+ +++ Sbjct: 877 CISKPCMNHGLCHN--TQGSYMCECPPGFSGMDCEEDIDDCLANPCQNGGSCMDGVNTFS 934 Query: 404 CACPVTYTGKNCE 442 C C +TG C+ Sbjct: 935 CLCLPGFTGDKCQ 947 Score = 59.7 bits (138), Expect = 6e-09 Identities = 29/84 (34%), Positives = 41/84 (48%), Gaps = 3/84 (3%) Frame = +2 Query: 200 KENVQNCFTCAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLC---GP 370 +EN+ +C P+ CLN G C + + GY C C PGF G C+ C C G Sbjct: 1223 EENIDDCAR-GPH-CLNGGQCMDRIG--GYSCRCLPGFAGERCEGDINECLSNPCSSEGS 1278 Query: 371 GKCMNTADSYKCACPVTYTGKNCE 442 C+ + Y C C +TG++CE Sbjct: 1279 LDCIQLTNDYLCVCRSAFTGRHCE 1302 Score = 58.8 bits (136), Expect = 1e-08 Identities = 27/71 (38%), Positives = 35/71 (49%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLCGPGKCMNTADSYKC 406 C+ CLN C + +GY C CA GF G C+ ++C P C G+C + DSY C Sbjct: 536 CSSTPCLNGAKCIDH--PNGYECQCATGFTGVLCEENIDNCDPDPCHHGQCQDGIDSYTC 593 Query: 407 ACPVTYTGKNC 439 C Y G C Sbjct: 594 ICNPGYMGAIC 604 Score = 57.6 bits (133), Expect = 3e-08 Identities = 31/95 (32%), Positives = 42/95 (44%), Gaps = 2/95 (2%) Frame = +2 Query: 203 ENVQNCFTCAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLCGPGK-C 379 E+V C PN C N G C A GY C+C G+ G++C + C C PG C Sbjct: 297 EDVDECLL-QPNACQNGGTC--ANRNGGYGCVCVNGWSGDDCSENIDDCAFASCTPGSTC 353 Query: 380 MNTADSYKCACPVTYTGKNCEVKQ-LIEYPAFTGS 481 ++ S+ C CP G C + I P G+ Sbjct: 354 IDRVASFSCMCPEGKAGLLCHLDDACISNPCHKGA 388 Score = 57.6 bits (133), Expect = 3e-08 Identities = 23/74 (31%), Positives = 40/74 (54%), Gaps = 1/74 (1%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLC-GPGKCMNTADSYK 403 C + C N+ C + + G+ CLC PGF G +C+ C+ C G+C++ + ++ Sbjct: 460 CHSDPCQNDATCLDKIG--GFTCLCMPGFKGVHCELEINECQSNPCVNNGQCVDKVNRFQ 517 Query: 404 CACPVTYTGKNCEV 445 C CP +TG C++ Sbjct: 518 CLCPPGFTGPVCQI 531 Score = 57.2 bits (132), Expect = 3e-08 Identities = 27/73 (36%), Positives = 37/73 (50%), Gaps = 1/73 (1%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLCGPG-KCMNTADSYK 403 C N C+NNG C + + + CLC PGF G C + C C G KC++ + Y+ Sbjct: 498 CQSNPCVNNGQCVDKVNR--FQCLCPPGFTGPVCQIDIDDCSSTPCLNGAKCIDHPNGYE 555 Query: 404 CACPVTYTGKNCE 442 C C +TG CE Sbjct: 556 CQCATGFTGVLCE 568 Score = 57.2 bits (132), Expect = 3e-08 Identities = 28/83 (33%), Positives = 45/83 (54%), Gaps = 1/83 (1%) Frame = +2 Query: 200 KENVQNCFTCAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNC-DRIGESCRPGLCGPGK 376 +EN+ NC P+ C ++G CQ+ + Y C+C PG+ G C D+I E G+ Sbjct: 568 EENIDNC---DPDPC-HHGQCQDGIDS--YTCICNPGYMGAICSDQIDECYSSPCLNDGR 621 Query: 377 CMNTADSYKCACPVTYTGKNCEV 445 C++ + Y+C C +G NCE+ Sbjct: 622 CIDLVNGYQCNCQPGTSGVNCEI 644 Score = 57.2 bits (132), Expect = 3e-08 Identities = 28/87 (32%), Positives = 38/87 (43%), Gaps = 3/87 (3%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLC-GPGKCMNTADSYK 403 C N C N G C + + + CLC PGF G+ C C C G C + +SY Sbjct: 915 CLANPCQNGGSCMDGVNT--FSCLCLPGFTGDKCQTDMNECLSEPCKNGGTCSDYVNSYT 972 Query: 404 CACPVTYTGKNCE--VKQLIEYPAFTG 478 C C + G +CE + + E F G Sbjct: 973 CKCQAGFDGVHCENNINECTESSCFNG 999 Score = 57.2 bits (132), Expect = 3e-08 Identities = 26/83 (31%), Positives = 39/83 (46%), Gaps = 3/83 (3%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLC-GPGKCMNTADSYK 403 C C N G C + + + Y C C GF G +C+ C C G C++ +S+ Sbjct: 953 CLSEPCKNGGTCSDYV--NSYTCKCQAGFDGVHCENNINECTESSCFNGGTCVDGINSFS 1010 Query: 404 CACPVTYTGKNC--EVKQLIEYP 466 C CPV +TG C E+ + +P Sbjct: 1011 CLCPVGFTGSFCLHEINECSSHP 1033 Score = 56.0 bits (129), Expect = 8e-08 Identities = 35/99 (35%), Positives = 44/99 (44%), Gaps = 6/99 (6%) Frame = +2 Query: 203 ENVQNCFTCAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCD-RIGESC---RPGLCGP 370 E Q+ C N C N G C C CA GF G +C C RP L G Sbjct: 60 EYCQHRDPCEKNRCQNGGTCVAQAMLGKATCRCASGFTGEDCQYSTSHPCFVSRPCLNG- 118 Query: 371 GKC-MNTADSYKCACPVTYTGKNCE-VKQLIEYPAFTGS 481 G C M + D+Y+C C V +TGK C+ + +P GS Sbjct: 119 GTCHMLSRDTYECTCQVGFTGKECQWTDACLSHPCANGS 157 Score = 55.6 bits (128), Expect = 1e-07 Identities = 25/73 (34%), Positives = 37/73 (50%), Gaps = 1/73 (1%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLC-GPGKCMNTADSYK 403 CA N C + C + + GY C C PG+ G NC+ + C+ C G C++ + +K Sbjct: 1153 CASNPCQHGATCSDFIG--GYRCECVPGYQGVNCEYEVDECQNQPCQNGGTCIDLVNHFK 1210 Query: 404 CACPVTYTGKNCE 442 C+CP G CE Sbjct: 1211 CSCPPGTRGLLCE 1223 Score = 55.2 bits (127), Expect = 1e-07 Identities = 26/88 (29%), Positives = 44/88 (50%), Gaps = 3/88 (3%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLCGPG-KCMNTADSYK 403 CA N C++ G+C + + Y C+C+PGF G C+ + C C G C+N + ++ Sbjct: 649 CASNPCIH-GICMDGINR--YSCVCSPGFTGQRCNIDIDECASNPCRKGATCINGVNGFR 705 Query: 404 CACPVTYTGKNC--EVKQLIEYPAFTGS 481 C CP +C +V + + P G+ Sbjct: 706 CICPEGPHHPSCYSQVNECLSNPCIHGN 733 Score = 54.0 bits (124), Expect = 3e-07 Identities = 25/74 (33%), Positives = 34/74 (45%), Gaps = 2/74 (2%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCR-PGLCGPG-KCMNTADSY 400 C + C N C + + C C GF G C+ C PG C G C+N SY Sbjct: 148 CLSHPCANGSTCTTVANQ--FSCKCLTGFTGQKCETDVNECDIPGHCQHGGTCLNLPGSY 205 Query: 401 KCACPVTYTGKNCE 442 +C CP +TG+ C+ Sbjct: 206 QCQCPQGFTGQYCD 219 Score = 53.6 bits (123), Expect = 4e-07 Identities = 27/74 (36%), Positives = 36/74 (48%), Gaps = 1/74 (1%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLC-GPGKCMNTADSYK 403 C N C++ G C L+ GY CLC G+ G NC+ C C G C N + Y+ Sbjct: 724 CLSNPCIH-GNCTGGLS--GYKCLCDAGWVGINCEVDKNECLSNPCQNGGTCDNLVNGYR 780 Query: 404 CACPVTYTGKNCEV 445 C C + G NC+V Sbjct: 781 CTCKKGFKGYNCQV 794 Score = 53.6 bits (123), Expect = 4e-07 Identities = 26/80 (32%), Positives = 36/80 (45%), Gaps = 3/80 (3%) Frame = +2 Query: 215 NCFTCAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLC-GPGKCMNTA 391 N CA N CLN G C + ++ GY C C + G NC + C P C C + Sbjct: 795 NIDECASNPCLNQGTCFDDIS--GYTCHCVLPYTGKNCQTVLAPCSPNPCENAAVCKESP 852 Query: 392 --DSYKCACPVTYTGKNCEV 445 +SY C C + G+ C + Sbjct: 853 NFESYTCLCAPGWQGQRCTI 872 Score = 52.0 bits (119), Expect = 1e-06 Identities = 24/74 (32%), Positives = 33/74 (44%), Gaps = 1/74 (1%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLC-GPGKCMNTADSYK 403 C+ + CLN G C + L Y C C G+ G NC + C C G C+ + Sbjct: 1029 CSSHPCLNEGTCVDGLGT--YRCSCPLGYTGKNCQTLVNLCSRSPCKNKGTCVQKKAESQ 1086 Query: 404 CACPVTYTGKNCEV 445 C CP + G C+V Sbjct: 1087 CLCPSGWAGAYCDV 1100 Score = 51.2 bits (117), Expect = 2e-06 Identities = 23/77 (29%), Positives = 32/77 (41%), Gaps = 4/77 (5%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLCGP----GKCMNTAD 394 C N C +C Y+C C G+ G +C + C P GKC+NT Sbjct: 379 CISNPCHKGALCDTNPLNGQYICTCPQGYKGADCTEDVDECAMANSNPCEHAGKCVNTDG 438 Query: 395 SYKCACPVTYTGKNCEV 445 ++ C C Y G CE+ Sbjct: 439 AFHCECLKGYAGPRCEM 455 Score = 50.8 bits (116), Expect = 3e-06 Identities = 36/98 (36%), Positives = 47/98 (47%), Gaps = 15/98 (15%) Frame = +2 Query: 212 QNCFT----CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESC-----RPG-- 358 +NC T C+ + C N G C + E CLC G+ G CD SC R G Sbjct: 1058 KNCQTLVNLCSRSPCKNKGTCVQKKAESQ--CLCPSGWAGAYCDVPNVSCDIAASRRGVL 1115 Query: 359 ---LCG-PGKCMNTADSYKCACPVTYTGKNCEVKQLIE 460 LC G C+N +++ C CP+ YTG CE +QL E Sbjct: 1116 VEHLCQHSGVCINAGNTHYCQCPLGYTGSYCE-EQLDE 1152 Score = 48.0 bits (109), Expect = 2e-05 Identities = 23/73 (31%), Positives = 29/73 (39%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLCGPGKCMNTADSYKC 406 CA N C C + +G+ C+C G +C C C G C YKC Sbjct: 686 CASNPCRKGATCINGV--NGFRCICPEGPHHPSCYSQVNECLSNPCIHGNCTGGLSGYKC 743 Query: 407 ACPVTYTGKNCEV 445 C + G NCEV Sbjct: 744 LCDAGWVGINCEV 756 Score = 47.6 bits (108), Expect = 3e-05 Identities = 24/72 (33%), Positives = 30/72 (41%), Gaps = 2/72 (2%) Frame = +2 Query: 233 PNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLC-GPGKCMNTAD-SYKC 406 P C + G C Y C C GF G CD + C P C G C T D +++C Sbjct: 189 PGHCQHGGTCLNL--PGSYQCQCPQGFTGQYCDSLYVPCAPSPCVNGGTCRQTGDFTFEC 246 Query: 407 ACPVTYTGKNCE 442 C + G CE Sbjct: 247 NCLPGFEGSTCE 258 Score = 47.2 bits (107), Expect = 4e-05 Identities = 24/74 (32%), Positives = 32/74 (43%), Gaps = 2/74 (2%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCR--PGLCGPGKCMNTADSY 400 C C N G C + L H + C C PG G C+ + C P G+CM+ Y Sbjct: 1191 CQNQPCQNGGTCID-LVNH-FKCSCPPGTRGLLCEENIDDCARGPHCLNGGQCMDRIGGY 1248 Query: 401 KCACPVTYTGKNCE 442 C C + G+ CE Sbjct: 1249 SCRCLPGFAGERCE 1262 Score = 46.0 bits (104), Expect = 8e-05 Identities = 24/79 (30%), Positives = 35/79 (44%), Gaps = 3/79 (3%) Frame = +2 Query: 212 QNCFTCAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESC--RPGLC-GPGKCM 382 +N C + C N GVC + + + Y C C P + G C + C +P C G C Sbjct: 259 RNIDDCPNHRCQNGGVCVDGV--NTYNCRCPPQWTGQFCTEDVDECLLQPNACQNGGTCA 316 Query: 383 NTADSYKCACPVTYTGKNC 439 N Y C C ++G +C Sbjct: 317 NRNGGYGCVCVNGWSGDDC 335 Score = 44.0 bits (99), Expect = 3e-04 Identities = 21/76 (27%), Positives = 32/76 (42%), Gaps = 4/76 (5%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLC-GPGKC---MNTAD 394 C N C + G + Y+C+C F G +C+ + C C G C N D Sbjct: 1268 CLSNPCSSEGSLDCIQLTNDYLCVCRSAFTGRHCETFVDVCPQMPCLNGGTCAVASNMPD 1327 Query: 395 SYKCACPVTYTGKNCE 442 + C CP ++G C+ Sbjct: 1328 GFICRCPPGFSGARCQ 1343 Score = 43.6 bits (98), Expect = 4e-04 Identities = 21/83 (25%), Positives = 34/83 (40%), Gaps = 1/83 (1%) Frame = +2 Query: 203 ENVQNCFTCAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLC-GPGKC 379 E+V C N C + G C T+ + C C G+ G C+ C C C Sbjct: 414 EDVDECAMANSNPCEHAGKCVN--TDGAFHCECLKGYAGPRCEMDINECHSDPCQNDATC 471 Query: 380 MNTADSYKCACPVTYTGKNCEVK 448 ++ + C C + G +CE++ Sbjct: 472 LDKIGGFTCLCMPGFKGVHCELE 494 Score = 35.1 bits (77), Expect = 0.16 Identities = 19/62 (30%), Positives = 24/62 (38%), Gaps = 2/62 (3%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCD--RIGESCRPGLCGPGKCMNTADSY 400 CA + C + G C Y C CAP F G+ C+ S P C C + A Sbjct: 1378 CASSPCQHGGSCHPQRQPPYYSCQCAPPFSGSRCELYTAPPSTPPATCLSQYCADKARDG 1437 Query: 401 KC 406 C Sbjct: 1438 VC 1439 >AF003837-1|AAC51731.1| 1218|Homo sapiens Jagged1 protein. Length = 1218 Score = 70.1 bits (164), Expect = 5e-12 Identities = 32/72 (44%), Positives = 37/72 (51%), Gaps = 1/72 (1%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLCGPG-KCMNTADSYK 403 CA N CL+ G CQ + + CLC GF GN C + C P C G +C N A Y Sbjct: 491 CASNPCLDGGHCQNEINR--FQCLCPTGFSGNLCQLDIDYCEPNPCQNGAQCYNRASDYF 548 Query: 404 CACPVTYTGKNC 439 C CP Y GKNC Sbjct: 549 CKCPEDYEGKNC 560 Score = 64.5 bits (150), Expect = 2e-10 Identities = 27/74 (36%), Positives = 39/74 (52%), Gaps = 1/74 (1%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLCGPG-KCMNTADSYK 403 C + C N G C+E T G+ C C+PG+ G C + C P C G C + + +K Sbjct: 340 CLSDPCHNRGSCKE--TSLGFECECSPGWTGPTCSTNIDDCSPNNCSHGGTCQDLVNGFK 397 Query: 404 CACPVTYTGKNCEV 445 C CP +TGK C++ Sbjct: 398 CVCPPQWTGKTCQL 411 Score = 63.3 bits (147), Expect = 5e-10 Identities = 27/78 (34%), Positives = 42/78 (53%), Gaps = 1/78 (1%) Frame = +2 Query: 212 QNCFTCAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLCGPG-KCMNT 388 QN C+P+ C N+G C + ++ Y C CAPGF G +C C+ C G C++ Sbjct: 781 QNTNDCSPHPCYNSGTCVDG--DNWYRCECAPGFAGPDCRININECQSSPCAFGATCVDE 838 Query: 389 ADSYKCACPVTYTGKNCE 442 + Y+C CP ++G C+ Sbjct: 839 INGYRCVCPPGHSGAKCQ 856 Score = 59.7 bits (138), Expect = 6e-09 Identities = 22/69 (31%), Positives = 40/69 (57%), Gaps = 1/69 (1%) Frame = +2 Query: 242 CLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLC-GPGKCMNTADSYKCACPV 418 C N+ C++ + +GY C+C PG+ G++C+R + C C G C N + ++C CP Sbjct: 458 CQNDASCRDLV--NGYRCICPPGYAGDHCERDIDECASNPCLDGGHCQNEINRFQCLCPT 515 Query: 419 TYTGKNCEV 445 ++G C++ Sbjct: 516 GFSGNLCQL 524 Score = 58.4 bits (135), Expect = 1e-08 Identities = 26/78 (33%), Positives = 38/78 (48%), Gaps = 1/78 (1%) Frame = +2 Query: 215 NCFTCAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLCGPGK-CMNTA 391 N C+PN C + G CQ+ + +G+ C+C P + G C C C K C N Sbjct: 374 NIDDCSPNNCSHGGTCQDLV--NGFKCVCPPQWTGKTCQLDANECEAKPCVNAKSCKNLI 431 Query: 392 DSYKCACPVTYTGKNCEV 445 SY C C + G+NC++ Sbjct: 432 ASYYCDCLPGWMGQNCDI 449 Score = 58.0 bits (134), Expect = 2e-08 Identities = 31/82 (37%), Positives = 43/82 (52%), Gaps = 4/82 (4%) Frame = +2 Query: 218 CFTCAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESC---RPGLCGPGKCMNT 388 C C P+ +G+C E + CLC +GG CD+ C +P L G G C NT Sbjct: 262 CDKCIPHPGCVHGICNEP-----WQCLCETNWGGQLCDKDLNYCGTHQPCLNG-GTCSNT 315 Query: 389 A-DSYKCACPVTYTGKNCEVKQ 451 D Y+C+CP Y+G NCE+ + Sbjct: 316 GPDKYQCSCPEGYSGPNCEIAE 337 Score = 54.4 bits (125), Expect = 2e-07 Identities = 23/78 (29%), Positives = 35/78 (44%), Gaps = 1/78 (1%) Frame = +2 Query: 215 NCFTCAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLCGPG-KCMNTA 391 N C+ N C N G C++ + + + C C G+ G C C C G C + Sbjct: 667 NINDCSQNPCHNGGTCRDLVND--FYCDCKNGWKGKTCHSRDSQCDEATCNNGGTCYDEG 724 Query: 392 DSYKCACPVTYTGKNCEV 445 D++KC CP + G C + Sbjct: 725 DAFKCMCPGGWEGTTCNI 742 Score = 53.6 bits (123), Expect = 4e-07 Identities = 23/81 (28%), Positives = 37/81 (45%), Gaps = 1/81 (1%) Frame = +2 Query: 206 NVQNCFTCAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLC-GPGKCM 382 N+ +C PN C N G C + + C+C G+ G C + C P C G C+ Sbjct: 741 NIARNSSCLPNPCHNGGTC--VVNGESFTCVCKEGWEGPICAQNTNDCSPHPCYNSGTCV 798 Query: 383 NTADSYKCACPVTYTGKNCEV 445 + + Y+C C + G +C + Sbjct: 799 DGDNWYRCECAPGFAGPDCRI 819 Score = 53.2 bits (122), Expect = 6e-07 Identities = 23/72 (31%), Positives = 31/72 (43%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLCGPGKCMNTADSYKC 406 C C+N C+ + Y C C PG+ G NCD C C + + Y+C Sbjct: 416 CEAKPCVNAKSCKNLIAS--YYCDCLPGWMGQNCDININDCLGQCQNDASCRDLVNGYRC 473 Query: 407 ACPVTYTGKNCE 442 CP Y G +CE Sbjct: 474 ICPPGYAGDHCE 485 Score = 50.8 bits (116), Expect = 3e-06 Identities = 25/80 (31%), Positives = 36/80 (45%), Gaps = 1/80 (1%) Frame = +2 Query: 203 ENVQNCFTCAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLC-GPGKC 379 +++ C T P CLN G C + Y C C G+ G NC+ +C C G C Sbjct: 295 KDLNYCGTHQP--CLNGGTCSNTGPDK-YQCSCPEGYSGPNCEIAEHACLSDPCHNRGSC 351 Query: 380 MNTADSYKCACPVTYTGKNC 439 T+ ++C C +TG C Sbjct: 352 KETSLGFECECSPGWTGPTC 371 Score = 48.4 bits (110), Expect = 2e-05 Identities = 22/77 (28%), Positives = 34/77 (44%), Gaps = 1/77 (1%) Frame = +2 Query: 212 QNCFTCAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLC-GPGKCMNT 388 +N C N C N G C + + + Y C+C+ G+ G C+ C C G C + Sbjct: 628 ENINDCESNPCRNGGTCIDGV--NSYKCICSDGWEGAYCETNINDCSQNPCHNGGTCRDL 685 Query: 389 ADSYKCACPVTYTGKNC 439 + + C C + GK C Sbjct: 686 VNDFYCDCKNGWKGKTC 702 Score = 43.6 bits (98), Expect = 4e-04 Identities = 22/70 (31%), Positives = 31/70 (44%), Gaps = 1/70 (1%) Frame = +2 Query: 236 NLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLC-GPGKCMNTADSYKCAC 412 N+C +G C+ + + C C GF G C C C G C++ +SYKC C Sbjct: 597 NVCGPHGKCKSQ-SGGKFTCDCNKGFTGTYCHENINDCESNPCRNGGTCIDGVNSYKCIC 655 Query: 413 PVTYTGKNCE 442 + G CE Sbjct: 656 SDGWEGAYCE 665 Score = 37.9 bits (84), Expect = 0.022 Identities = 15/46 (32%), Positives = 20/46 (43%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLC 364 C PN C N C ++ Y C C + G NC + + CR C Sbjct: 529 CEPNPCQNGAQCYNRASD--YFCKCPEDYEGKNCSHLKDHCRTTPC 572 Score = 31.5 bits (68), Expect = 1.9 Identities = 14/46 (30%), Positives = 20/46 (43%), Gaps = 1/46 (2%) Frame = +2 Query: 215 NCFTCAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRI-GESC 349 N C + C C + + +GY C+C PG G C + G C Sbjct: 820 NINECQSSPCAFGATCVDEI--NGYRCVCPPGHSGAKCQEVSGRPC 863 >AY043325-1|AAL10682.1| 1406|Homo sapiens CRB1 isoform II precursor protein. Length = 1406 Score = 69.7 bits (163), Expect = 6e-12 Identities = 29/75 (38%), Positives = 39/75 (52%), Gaps = 1/75 (1%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLC-GPGKCMNTADSYK 403 CA + C N VCQ+ + GY C C PG+ G +CD + C C C+N Y Sbjct: 152 CASSPCQNGAVCQDGID--GYSCFCVPGYQGRHCDLEVDECASDPCKNEATCLNEIGRYT 209 Query: 404 CACPVTYTGKNCEVK 448 C CP Y+G NCE++ Sbjct: 210 CICPHNYSGVNCELE 224 Score = 58.8 bits (136), Expect = 1e-08 Identities = 26/73 (35%), Positives = 36/73 (49%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLCGPGKCMNTADSYKC 406 C N CL+ G C++ + Y C C G+ G +C+ + C C G C + +Y C Sbjct: 1143 CNSNPCLHGGNCEDIYSS--YHCSCPLGWSGKHCELNIDECFSNPCIHGNCSDRVAAYHC 1200 Query: 407 ACPVTYTGKNCEV 445 C YTG NCEV Sbjct: 1201 TCEPGYTGVNCEV 1213 Score = 56.4 bits (130), Expect = 6e-08 Identities = 25/69 (36%), Positives = 35/69 (50%), Gaps = 1/69 (1%) Frame = +2 Query: 242 CLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLC-GPGKCMNTADSYKCACPV 418 C N G C E TE C+C PGF G C++ + C C G C + + ++C C V Sbjct: 1268 CYNGGNCTEFQTE--LKCMCRPGFTGEWCEKDIDECASDPCVNGGLCQDLLNKFQCLCDV 1325 Query: 419 TYTGKNCEV 445 + G+ CEV Sbjct: 1326 AFAGERCEV 1334 Score = 56.0 bits (129), Expect = 8e-08 Identities = 30/75 (40%), Positives = 42/75 (56%), Gaps = 3/75 (4%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESC--RPGLCGPGKCMNTADSY 400 C CLN CQ+AL Y C CAPGF G++C+ + C +P L G G C++ + Y Sbjct: 228 CWSQPCLNGATCQDALG--AYFCDCAPGFLGDHCELNTDECASQPCLHG-GLCVDGENRY 284 Query: 401 KCACPVT-YTGKNCE 442 C C + +TG +CE Sbjct: 285 SCNCTGSGFTGTHCE 299 Score = 53.6 bits (123), Expect = 4e-07 Identities = 27/84 (32%), Positives = 43/84 (51%), Gaps = 1/84 (1%) Frame = +2 Query: 206 NVQNCFTCAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLCGPG-KCM 382 N+ CF+ N C++ G C + + Y C C PG+ G NC+ ++C+ C G C+ Sbjct: 1177 NIDECFS---NPCIH-GNCSDRVA--AYHCTCEPGYTGVNCEVDIDNCQSHQCANGATCI 1230 Query: 383 NTADSYKCACPVTYTGKNCEVKQL 454 + + Y C C +TGK C +L Sbjct: 1231 SHTNGYSCLCFGNFTGKFCRQSRL 1254 Score = 52.8 bits (121), Expect = 7e-07 Identities = 23/74 (31%), Positives = 31/74 (41%), Gaps = 1/74 (1%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLCGPGKCMNTADSYK- 403 C N C + C E ++C C PG+ G C+ SC C G + Y Sbjct: 74 CFSNPCQGSATCVNTPGERSFLCKCPPGYSGTICETTIGSCGKNSCQHGGICHQDPIYPV 133 Query: 404 CACPVTYTGKNCEV 445 C CP Y G+ CE+ Sbjct: 134 CICPAGYAGRFCEI 147 Score = 52.8 bits (121), Expect = 7e-07 Identities = 27/79 (34%), Positives = 38/79 (48%), Gaps = 2/79 (2%) Frame = +2 Query: 215 NCFTCAPNLCLNNGVCQEALTEHGYVCLCA-PGFGGNNCDRIGESCRPGLC-GPGKCMNT 388 N CA CL+ G+C + E+ Y C C GF G +C+ + C C C ++ Sbjct: 262 NTDECASQPCLHGGLCVDG--ENRYSCNCTGSGFTGTHCETLMPLCWSKPCHNNATCEDS 319 Query: 389 ADSYKCACPVTYTGKNCEV 445 D+Y C C YTG CE+ Sbjct: 320 VDNYTCHCWPGYTGAQCEI 338 Score = 51.6 bits (118), Expect = 2e-06 Identities = 23/77 (29%), Positives = 38/77 (49%), Gaps = 2/77 (2%) Frame = +2 Query: 224 TCAPNLCLNNGVC-QEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLCGPGK-CMNTADS 397 +C N C + G+C Q+ + VC+C G+ G C+ + C C G C + D Sbjct: 113 SCGKNSCQHGGICHQDPIYP---VCICPAGYAGRFCEIDHDECASSPCQNGAVCQDGIDG 169 Query: 398 YKCACPVTYTGKNCEVK 448 Y C C Y G++C+++ Sbjct: 170 YSCFCVPGYQGRHCDLE 186 Score = 47.2 bits (107), Expect = 4e-05 Identities = 19/45 (42%), Positives = 23/45 (51%), Gaps = 1/45 (2%) Frame = +2 Query: 284 GYVCLCAPGFGGNNCDRIGESCRPGLC-GPGKCMNTADSYKCACP 415 GYVC+C PGF G +C+ C C G C N +Y C CP Sbjct: 380 GYVCICQPGFTGIHCEEDVNECSSNPCQNGGTCENLPGNYTCHCP 424 Score = 46.8 bits (106), Expect = 5e-05 Identities = 24/80 (30%), Positives = 35/80 (43%), Gaps = 3/80 (3%) Frame = +2 Query: 212 QNCFTCAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLC-GPGKCMNT 388 +N C N C NN C++ ++ C +CD + + C C G C+NT Sbjct: 29 KNNTRCLSNSCQNNSTCKDFSKDNDCSCSDTANNLDKDCDNMKDPCFSNPCQGSATCVNT 88 Query: 389 AD--SYKCACPVTYTGKNCE 442 S+ C CP Y+G CE Sbjct: 89 PGERSFLCKCPPGYSGTICE 108 Score = 45.2 bits (102), Expect = 1e-04 Identities = 24/75 (32%), Positives = 34/75 (45%), Gaps = 2/75 (2%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHG-YVCLCAPGFGGNNCDRIGESCRPGLCGPG-KCMNTADSY 400 CA + C N C L E G Y C+C + G NC+ + C C G C + +Y Sbjct: 190 CASDPCKNEATC---LNEIGRYTCICPHNYSGVNCELEIDECWSQPCLNGATCQDALGAY 246 Query: 401 KCACPVTYTGKNCEV 445 C C + G +CE+ Sbjct: 247 FCDCAPGFLGDHCEL 261 Score = 42.7 bits (96), Expect = 8e-04 Identities = 38/151 (25%), Positives = 61/151 (40%), Gaps = 12/151 (7%) Frame = +2 Query: 29 SPDQWTVLELNQPLYIGGVPDFDQLPIDLAGASGFVGCISMLILGNEE-------KNIMA 187 S W + E +YIGG+PD + ++ F GCI + L N+ N + Sbjct: 818 SASTWKI-EKGDVIYIGGLPDKQETELN---GGFFKGCIQDVRLNNQNLEFFPNPTNNAS 873 Query: 188 LALEKENV-QNCF---TCAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRP 355 L NV Q C +C N C N GVC + + C C G C+ + + C Sbjct: 874 LNPVLVNVTQGCAGDNSCKSNPCHNGGVCHSRWDD--FSCSCPALTSGKACEEV-QWCGF 930 Query: 356 GLCGPG-KCMNTADSYKCACPVTYTGKNCEV 445 C G +C ++C + G++ ++ Sbjct: 931 SPCPHGAQCQPVLQGFECIANAVFNGQSGQI 961 Score = 40.7 bits (91), Expect = 0.003 Identities = 24/88 (27%), Positives = 35/88 (39%), Gaps = 9/88 (10%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVC----LCAPGFGGNNCDRIGESCRPGLC-GPGKCM--- 382 C+ N C N G C+ + C L +GG +C I C C G C+ Sbjct: 401 CSSNPCQNGGTCENLPGNYTCHCPFDNLSRTFYGGRDCSDILLGCTHQQCLNNGTCIPHF 460 Query: 383 -NTADSYKCACPVTYTGKNCEVKQLIEY 463 + + C CP YTG CE+ + + Sbjct: 461 QDGQHGFSCLCPSGYTGSLCEIATTLSF 488 Score = 37.1 bits (82), Expect = 0.039 Identities = 14/35 (40%), Positives = 21/35 (60%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCD 331 CA + C+N G+CQ+ L + + CLC F G C+ Sbjct: 1301 CASDPCVNGGLCQDLLNK--FQCLCDVAFAGERCE 1333 Score = 35.5 bits (78), Expect = 0.12 Identities = 22/89 (24%), Positives = 35/89 (39%), Gaps = 5/89 (5%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLC-GPGKCMNTADSYK 403 C C NN C++++ Y C C PG+ G C+ C C G+C+ + + Sbjct: 305 CWSKPCHNNATCEDSVDN--YTCHCWPGYTGAQCEIDLNECNSNPCQSNGECVELSSEKQ 362 Query: 404 ----CACPVTYTGKNCEVKQLIEYPAFTG 478 P +++ I P FTG Sbjct: 363 YGRITGLPSSFSYHEASGYVCICQPGFTG 391 Score = 33.1 bits (72), Expect = 0.63 Identities = 14/37 (37%), Positives = 19/37 (51%), Gaps = 1/37 (2%) Frame = +2 Query: 344 SCRPGLC-GPGKCMNTADSYKCACPVTYTGKNCEVKQ 451 SC+ C G C + D + C+CP +GK CE Q Sbjct: 890 SCKSNPCHNGGVCHSRWDDFSCSCPALTSGKACEEVQ 926 Score = 29.9 bits (64), Expect = 5.9 Identities = 11/23 (47%), Positives = 14/23 (60%) Frame = +2 Query: 371 GKCMNTADSYKCACPVTYTGKNC 439 G+C+N SY+C C Y G NC Sbjct: 685 GRCINLWLSYQCDCHRPYEGPNC 707 >AY043324-1|AAL10681.1| 1376|Homo sapiens CRB1 isoform I precursor protein. Length = 1376 Score = 69.7 bits (163), Expect = 6e-12 Identities = 29/75 (38%), Positives = 39/75 (52%), Gaps = 1/75 (1%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLC-GPGKCMNTADSYK 403 CA + C N VCQ+ + GY C C PG+ G +CD + C C C+N Y Sbjct: 152 CASSPCQNGAVCQDGID--GYSCFCVPGYQGRHCDLEVDECASDPCKNEATCLNEIGRYT 209 Query: 404 CACPVTYTGKNCEVK 448 C CP Y+G NCE++ Sbjct: 210 CICPHNYSGVNCELE 224 Score = 58.8 bits (136), Expect = 1e-08 Identities = 26/73 (35%), Positives = 36/73 (49%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLCGPGKCMNTADSYKC 406 C N CL+ G C++ + Y C C G+ G +C+ + C C G C + +Y C Sbjct: 1143 CNSNPCLHGGNCEDIYSS--YHCSCPLGWSGKHCELNIDECFSNPCIHGNCSDRVAAYHC 1200 Query: 407 ACPVTYTGKNCEV 445 C YTG NCEV Sbjct: 1201 TCEPGYTGVNCEV 1213 Score = 56.4 bits (130), Expect = 6e-08 Identities = 25/69 (36%), Positives = 35/69 (50%), Gaps = 1/69 (1%) Frame = +2 Query: 242 CLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLC-GPGKCMNTADSYKCACPV 418 C N G C E TE C+C PGF G C++ + C C G C + + ++C C V Sbjct: 1268 CYNGGNCTEFQTE--LKCMCRPGFTGEWCEKDIDECASDPCVNGGLCQDLLNKFQCLCDV 1325 Query: 419 TYTGKNCEV 445 + G+ CEV Sbjct: 1326 AFAGERCEV 1334 Score = 56.0 bits (129), Expect = 8e-08 Identities = 30/75 (40%), Positives = 42/75 (56%), Gaps = 3/75 (4%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESC--RPGLCGPGKCMNTADSY 400 C CLN CQ+AL Y C CAPGF G++C+ + C +P L G G C++ + Y Sbjct: 228 CWSQPCLNGATCQDALG--AYFCDCAPGFLGDHCELNTDECASQPCLHG-GLCVDGENRY 284 Query: 401 KCACPVT-YTGKNCE 442 C C + +TG +CE Sbjct: 285 SCNCTGSGFTGTHCE 299 Score = 53.6 bits (123), Expect = 4e-07 Identities = 27/84 (32%), Positives = 43/84 (51%), Gaps = 1/84 (1%) Frame = +2 Query: 206 NVQNCFTCAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLCGPG-KCM 382 N+ CF+ N C++ G C + + Y C C PG+ G NC+ ++C+ C G C+ Sbjct: 1177 NIDECFS---NPCIH-GNCSDRVA--AYHCTCEPGYTGVNCEVDIDNCQSHQCANGATCI 1230 Query: 383 NTADSYKCACPVTYTGKNCEVKQL 454 + + Y C C +TGK C +L Sbjct: 1231 SHTNGYSCLCFGNFTGKFCRQSRL 1254 Score = 52.8 bits (121), Expect = 7e-07 Identities = 23/74 (31%), Positives = 31/74 (41%), Gaps = 1/74 (1%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLCGPGKCMNTADSYK- 403 C N C + C E ++C C PG+ G C+ SC C G + Y Sbjct: 74 CFSNPCQGSATCVNTPGERSFLCKCPPGYSGTICETTIGSCGKNSCQHGGICHQDPIYPV 133 Query: 404 CACPVTYTGKNCEV 445 C CP Y G+ CE+ Sbjct: 134 CICPAGYAGRFCEI 147 Score = 52.8 bits (121), Expect = 7e-07 Identities = 27/79 (34%), Positives = 38/79 (48%), Gaps = 2/79 (2%) Frame = +2 Query: 215 NCFTCAPNLCLNNGVCQEALTEHGYVCLCA-PGFGGNNCDRIGESCRPGLC-GPGKCMNT 388 N CA CL+ G+C + E+ Y C C GF G +C+ + C C C ++ Sbjct: 262 NTDECASQPCLHGGLCVDG--ENRYSCNCTGSGFTGTHCETLMPLCWSKPCHNNATCEDS 319 Query: 389 ADSYKCACPVTYTGKNCEV 445 D+Y C C YTG CE+ Sbjct: 320 VDNYTCHCWPGYTGAQCEI 338 Score = 51.6 bits (118), Expect = 2e-06 Identities = 23/77 (29%), Positives = 38/77 (49%), Gaps = 2/77 (2%) Frame = +2 Query: 224 TCAPNLCLNNGVC-QEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLCGPGK-CMNTADS 397 +C N C + G+C Q+ + VC+C G+ G C+ + C C G C + D Sbjct: 113 SCGKNSCQHGGICHQDPIYP---VCICPAGYAGRFCEIDHDECASSPCQNGAVCQDGIDG 169 Query: 398 YKCACPVTYTGKNCEVK 448 Y C C Y G++C+++ Sbjct: 170 YSCFCVPGYQGRHCDLE 186 Score = 47.2 bits (107), Expect = 4e-05 Identities = 19/45 (42%), Positives = 23/45 (51%), Gaps = 1/45 (2%) Frame = +2 Query: 284 GYVCLCAPGFGGNNCDRIGESCRPGLC-GPGKCMNTADSYKCACP 415 GYVC+C PGF G +C+ C C G C N +Y C CP Sbjct: 380 GYVCICQPGFTGIHCEEDVNECSSNPCQNGGTCENLPGNYTCHCP 424 Score = 46.8 bits (106), Expect = 5e-05 Identities = 24/80 (30%), Positives = 35/80 (43%), Gaps = 3/80 (3%) Frame = +2 Query: 212 QNCFTCAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLC-GPGKCMNT 388 +N C N C NN C++ ++ C +CD + + C C G C+NT Sbjct: 29 KNNTRCLSNSCQNNSTCKDFSKDNDCSCSDTANNLDKDCDNMKDPCFSNPCQGSATCVNT 88 Query: 389 AD--SYKCACPVTYTGKNCE 442 S+ C CP Y+G CE Sbjct: 89 PGERSFLCKCPPGYSGTICE 108 Score = 45.2 bits (102), Expect = 1e-04 Identities = 24/75 (32%), Positives = 34/75 (45%), Gaps = 2/75 (2%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHG-YVCLCAPGFGGNNCDRIGESCRPGLCGPG-KCMNTADSY 400 CA + C N C L E G Y C+C + G NC+ + C C G C + +Y Sbjct: 190 CASDPCKNEATC---LNEIGRYTCICPHNYSGVNCELEIDECWSQPCLNGATCQDALGAY 246 Query: 401 KCACPVTYTGKNCEV 445 C C + G +CE+ Sbjct: 247 FCDCAPGFLGDHCEL 261 Score = 42.7 bits (96), Expect = 8e-04 Identities = 38/151 (25%), Positives = 61/151 (40%), Gaps = 12/151 (7%) Frame = +2 Query: 29 SPDQWTVLELNQPLYIGGVPDFDQLPIDLAGASGFVGCISMLILGNEE-------KNIMA 187 S W + E +YIGG+PD + ++ F GCI + L N+ N + Sbjct: 818 SASTWKI-EKGDVIYIGGLPDKQETELN---GGFFKGCIQDVRLNNQNLEFFPNPTNNAS 873 Query: 188 LALEKENV-QNCF---TCAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRP 355 L NV Q C +C N C N GVC + + C C G C+ + + C Sbjct: 874 LNPVLVNVTQGCAGDNSCKSNPCHNGGVCHSRWDD--FSCSCPALTSGKACEEV-QWCGF 930 Query: 356 GLCGPG-KCMNTADSYKCACPVTYTGKNCEV 445 C G +C ++C + G++ ++ Sbjct: 931 SPCPHGAQCQPVLQGFECIANAVFNGQSGQI 961 Score = 40.7 bits (91), Expect = 0.003 Identities = 24/88 (27%), Positives = 35/88 (39%), Gaps = 9/88 (10%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVC----LCAPGFGGNNCDRIGESCRPGLC-GPGKCM--- 382 C+ N C N G C+ + C L +GG +C I C C G C+ Sbjct: 401 CSSNPCQNGGTCENLPGNYTCHCPFDNLSRTFYGGRDCSDILLGCTHQQCLNNGTCIPHF 460 Query: 383 -NTADSYKCACPVTYTGKNCEVKQLIEY 463 + + C CP YTG CE+ + + Sbjct: 461 QDGQHGFSCLCPSGYTGSLCEIATTLSF 488 Score = 37.1 bits (82), Expect = 0.039 Identities = 14/35 (40%), Positives = 21/35 (60%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCD 331 CA + C+N G+CQ+ L + + CLC F G C+ Sbjct: 1301 CASDPCVNGGLCQDLLNK--FQCLCDVAFAGERCE 1333 Score = 35.5 bits (78), Expect = 0.12 Identities = 22/89 (24%), Positives = 35/89 (39%), Gaps = 5/89 (5%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLC-GPGKCMNTADSYK 403 C C NN C++++ Y C C PG+ G C+ C C G+C+ + + Sbjct: 305 CWSKPCHNNATCEDSVDN--YTCHCWPGYTGAQCEIDLNECNSNPCQSNGECVELSSEKQ 362 Query: 404 ----CACPVTYTGKNCEVKQLIEYPAFTG 478 P +++ I P FTG Sbjct: 363 YGRITGLPSSFSYHEASGYVCICQPGFTG 391 Score = 33.1 bits (72), Expect = 0.63 Identities = 14/37 (37%), Positives = 19/37 (51%), Gaps = 1/37 (2%) Frame = +2 Query: 344 SCRPGLC-GPGKCMNTADSYKCACPVTYTGKNCEVKQ 451 SC+ C G C + D + C+CP +GK CE Q Sbjct: 890 SCKSNPCHNGGVCHSRWDDFSCSCPALTSGKACEEVQ 926 Score = 29.9 bits (64), Expect = 5.9 Identities = 11/23 (47%), Positives = 14/23 (60%) Frame = +2 Query: 371 GKCMNTADSYKCACPVTYTGKNC 439 G+C+N SY+C C Y G NC Sbjct: 685 GRCINLWLSYQCDCHRPYEGPNC 707 >AL513325-2|CAH72584.1| 1406|Homo sapiens crumbs homolog 1 (Drosophila) protein. Length = 1406 Score = 69.7 bits (163), Expect = 6e-12 Identities = 29/75 (38%), Positives = 39/75 (52%), Gaps = 1/75 (1%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLC-GPGKCMNTADSYK 403 CA + C N VCQ+ + GY C C PG+ G +CD + C C C+N Y Sbjct: 152 CASSPCQNGAVCQDGID--GYSCFCVPGYQGRHCDLEVDECASDPCKNEATCLNEIGRYT 209 Query: 404 CACPVTYTGKNCEVK 448 C CP Y+G NCE++ Sbjct: 210 CICPHNYSGVNCELE 224 Score = 58.8 bits (136), Expect = 1e-08 Identities = 26/73 (35%), Positives = 36/73 (49%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLCGPGKCMNTADSYKC 406 C N CL+ G C++ + Y C C G+ G +C+ + C C G C + +Y C Sbjct: 1143 CNSNPCLHGGNCEDIYSS--YHCSCPLGWSGKHCELNIDECFSNPCIHGNCSDRVAAYHC 1200 Query: 407 ACPVTYTGKNCEV 445 C YTG NCEV Sbjct: 1201 TCEPGYTGVNCEV 1213 Score = 56.4 bits (130), Expect = 6e-08 Identities = 25/69 (36%), Positives = 35/69 (50%), Gaps = 1/69 (1%) Frame = +2 Query: 242 CLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLC-GPGKCMNTADSYKCACPV 418 C N G C E TE C+C PGF G C++ + C C G C + + ++C C V Sbjct: 1268 CYNGGNCTEFQTE--LKCMCRPGFTGEWCEKDIDECASDPCVNGGLCQDLLNKFQCLCDV 1325 Query: 419 TYTGKNCEV 445 + G+ CEV Sbjct: 1326 AFAGERCEV 1334 Score = 56.0 bits (129), Expect = 8e-08 Identities = 30/75 (40%), Positives = 42/75 (56%), Gaps = 3/75 (4%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESC--RPGLCGPGKCMNTADSY 400 C CLN CQ+AL Y C CAPGF G++C+ + C +P L G G C++ + Y Sbjct: 228 CWSQPCLNGATCQDALG--AYFCDCAPGFLGDHCELNTDECASQPCLHG-GLCVDGENRY 284 Query: 401 KCACPVT-YTGKNCE 442 C C + +TG +CE Sbjct: 285 SCNCTGSGFTGTHCE 299 Score = 53.6 bits (123), Expect = 4e-07 Identities = 27/84 (32%), Positives = 43/84 (51%), Gaps = 1/84 (1%) Frame = +2 Query: 206 NVQNCFTCAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLCGPG-KCM 382 N+ CF+ N C++ G C + + Y C C PG+ G NC+ ++C+ C G C+ Sbjct: 1177 NIDECFS---NPCIH-GNCSDRVA--AYHCTCEPGYTGVNCEVDIDNCQSHQCANGATCI 1230 Query: 383 NTADSYKCACPVTYTGKNCEVKQL 454 + + Y C C +TGK C +L Sbjct: 1231 SHTNGYSCLCFGNFTGKFCRQSRL 1254 Score = 52.8 bits (121), Expect = 7e-07 Identities = 23/74 (31%), Positives = 31/74 (41%), Gaps = 1/74 (1%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLCGPGKCMNTADSYK- 403 C N C + C E ++C C PG+ G C+ SC C G + Y Sbjct: 74 CFSNPCQGSATCVNTPGERSFLCKCPPGYSGTICETTIGSCGKNSCQHGGICHQDPIYPV 133 Query: 404 CACPVTYTGKNCEV 445 C CP Y G+ CE+ Sbjct: 134 CICPAGYAGRFCEI 147 Score = 52.8 bits (121), Expect = 7e-07 Identities = 27/79 (34%), Positives = 38/79 (48%), Gaps = 2/79 (2%) Frame = +2 Query: 215 NCFTCAPNLCLNNGVCQEALTEHGYVCLCA-PGFGGNNCDRIGESCRPGLC-GPGKCMNT 388 N CA CL+ G+C + E+ Y C C GF G +C+ + C C C ++ Sbjct: 262 NTDECASQPCLHGGLCVDG--ENRYSCNCTGSGFTGTHCETLMPLCWSKPCHNNATCEDS 319 Query: 389 ADSYKCACPVTYTGKNCEV 445 D+Y C C YTG CE+ Sbjct: 320 VDNYTCHCWPGYTGAQCEI 338 Score = 51.6 bits (118), Expect = 2e-06 Identities = 23/77 (29%), Positives = 38/77 (49%), Gaps = 2/77 (2%) Frame = +2 Query: 224 TCAPNLCLNNGVC-QEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLCGPGK-CMNTADS 397 +C N C + G+C Q+ + VC+C G+ G C+ + C C G C + D Sbjct: 113 SCGKNSCQHGGICHQDPIYP---VCICPAGYAGRFCEIDHDECASSPCQNGAVCQDGIDG 169 Query: 398 YKCACPVTYTGKNCEVK 448 Y C C Y G++C+++ Sbjct: 170 YSCFCVPGYQGRHCDLE 186 Score = 47.2 bits (107), Expect = 4e-05 Identities = 19/45 (42%), Positives = 23/45 (51%), Gaps = 1/45 (2%) Frame = +2 Query: 284 GYVCLCAPGFGGNNCDRIGESCRPGLC-GPGKCMNTADSYKCACP 415 GYVC+C PGF G +C+ C C G C N +Y C CP Sbjct: 380 GYVCICQPGFTGIHCEEDVNECSSNPCQNGGTCENLPGNYTCHCP 424 Score = 46.8 bits (106), Expect = 5e-05 Identities = 24/80 (30%), Positives = 35/80 (43%), Gaps = 3/80 (3%) Frame = +2 Query: 212 QNCFTCAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLC-GPGKCMNT 388 +N C N C NN C++ ++ C +CD + + C C G C+NT Sbjct: 29 KNNTRCLSNSCQNNSTCKDFSKDNDCSCSDTANNLDKDCDNMKDPCFSNPCQGSATCVNT 88 Query: 389 AD--SYKCACPVTYTGKNCE 442 S+ C CP Y+G CE Sbjct: 89 PGERSFLCKCPPGYSGTICE 108 Score = 45.2 bits (102), Expect = 1e-04 Identities = 24/75 (32%), Positives = 34/75 (45%), Gaps = 2/75 (2%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHG-YVCLCAPGFGGNNCDRIGESCRPGLCGPG-KCMNTADSY 400 CA + C N C L E G Y C+C + G NC+ + C C G C + +Y Sbjct: 190 CASDPCKNEATC---LNEIGRYTCICPHNYSGVNCELEIDECWSQPCLNGATCQDALGAY 246 Query: 401 KCACPVTYTGKNCEV 445 C C + G +CE+ Sbjct: 247 FCDCAPGFLGDHCEL 261 Score = 42.7 bits (96), Expect = 8e-04 Identities = 38/151 (25%), Positives = 61/151 (40%), Gaps = 12/151 (7%) Frame = +2 Query: 29 SPDQWTVLELNQPLYIGGVPDFDQLPIDLAGASGFVGCISMLILGNEE-------KNIMA 187 S W + E +YIGG+PD + ++ F GCI + L N+ N + Sbjct: 818 SASTWKI-EKGDVIYIGGLPDKQETELN---GGFFKGCIQDVRLNNQNLEFFPNPTNNAS 873 Query: 188 LALEKENV-QNCF---TCAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRP 355 L NV Q C +C N C N GVC + + C C G C+ + + C Sbjct: 874 LNPVLVNVTQGCAGDNSCKSNPCHNGGVCHSRWDD--FSCSCPALTSGKACEEV-QWCGF 930 Query: 356 GLCGPG-KCMNTADSYKCACPVTYTGKNCEV 445 C G +C ++C + G++ ++ Sbjct: 931 SPCPHGAQCQPVLQGFECIANAVFNGQSGQI 961 Score = 40.7 bits (91), Expect = 0.003 Identities = 24/88 (27%), Positives = 35/88 (39%), Gaps = 9/88 (10%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVC----LCAPGFGGNNCDRIGESCRPGLC-GPGKCM--- 382 C+ N C N G C+ + C L +GG +C I C C G C+ Sbjct: 401 CSSNPCQNGGTCENLPGNYTCHCPFDNLSRTFYGGRDCSDILLGCTHQQCLNNGTCIPHF 460 Query: 383 -NTADSYKCACPVTYTGKNCEVKQLIEY 463 + + C CP YTG CE+ + + Sbjct: 461 QDGQHGFSCLCPSGYTGSLCEIATTLSF 488 Score = 37.1 bits (82), Expect = 0.039 Identities = 14/35 (40%), Positives = 21/35 (60%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCD 331 CA + C+N G+CQ+ L + + CLC F G C+ Sbjct: 1301 CASDPCVNGGLCQDLLNK--FQCLCDVAFAGERCE 1333 Score = 35.5 bits (78), Expect = 0.12 Identities = 22/89 (24%), Positives = 35/89 (39%), Gaps = 5/89 (5%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLC-GPGKCMNTADSYK 403 C C NN C++++ Y C C PG+ G C+ C C G+C+ + + Sbjct: 305 CWSKPCHNNATCEDSVDN--YTCHCWPGYTGAQCEIDLNECNSNPCQSNGECVELSSEKQ 362 Query: 404 ----CACPVTYTGKNCEVKQLIEYPAFTG 478 P +++ I P FTG Sbjct: 363 YGRITGLPSSFSYHEASGYVCICQPGFTG 391 Score = 33.1 bits (72), Expect = 0.63 Identities = 14/37 (37%), Positives = 19/37 (51%), Gaps = 1/37 (2%) Frame = +2 Query: 344 SCRPGLC-GPGKCMNTADSYKCACPVTYTGKNCEVKQ 451 SC+ C G C + D + C+CP +GK CE Q Sbjct: 890 SCKSNPCHNGGVCHSRWDDFSCSCPALTSGKACEEVQ 926 Score = 29.9 bits (64), Expect = 5.9 Identities = 11/23 (47%), Positives = 14/23 (60%) Frame = +2 Query: 371 GKCMNTADSYKCACPVTYTGKNC 439 G+C+N SY+C C Y G NC Sbjct: 685 GRCINLWLSYQCDCHRPYEGPNC 707 >AL139136-2|CAI15311.1| 1406|Homo sapiens crumbs homolog 1 (Drosophila) protein. Length = 1406 Score = 69.7 bits (163), Expect = 6e-12 Identities = 29/75 (38%), Positives = 39/75 (52%), Gaps = 1/75 (1%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLC-GPGKCMNTADSYK 403 CA + C N VCQ+ + GY C C PG+ G +CD + C C C+N Y Sbjct: 152 CASSPCQNGAVCQDGID--GYSCFCVPGYQGRHCDLEVDECASDPCKNEATCLNEIGRYT 209 Query: 404 CACPVTYTGKNCEVK 448 C CP Y+G NCE++ Sbjct: 210 CICPHNYSGVNCELE 224 Score = 58.8 bits (136), Expect = 1e-08 Identities = 26/73 (35%), Positives = 36/73 (49%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLCGPGKCMNTADSYKC 406 C N CL+ G C++ + Y C C G+ G +C+ + C C G C + +Y C Sbjct: 1143 CNSNPCLHGGNCEDIYSS--YHCSCPLGWSGKHCELNIDECFSNPCIHGNCSDRVAAYHC 1200 Query: 407 ACPVTYTGKNCEV 445 C YTG NCEV Sbjct: 1201 TCEPGYTGVNCEV 1213 Score = 56.4 bits (130), Expect = 6e-08 Identities = 25/69 (36%), Positives = 35/69 (50%), Gaps = 1/69 (1%) Frame = +2 Query: 242 CLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLC-GPGKCMNTADSYKCACPV 418 C N G C E TE C+C PGF G C++ + C C G C + + ++C C V Sbjct: 1268 CYNGGNCTEFQTE--LKCMCRPGFTGEWCEKDIDECASDPCVNGGLCQDLLNKFQCLCDV 1325 Query: 419 TYTGKNCEV 445 + G+ CEV Sbjct: 1326 AFAGERCEV 1334 Score = 56.0 bits (129), Expect = 8e-08 Identities = 30/75 (40%), Positives = 42/75 (56%), Gaps = 3/75 (4%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESC--RPGLCGPGKCMNTADSY 400 C CLN CQ+AL Y C CAPGF G++C+ + C +P L G G C++ + Y Sbjct: 228 CWSQPCLNGATCQDALG--AYFCDCAPGFLGDHCELNTDECASQPCLHG-GLCVDGENRY 284 Query: 401 KCACPVT-YTGKNCE 442 C C + +TG +CE Sbjct: 285 SCNCTGSGFTGTHCE 299 Score = 53.6 bits (123), Expect = 4e-07 Identities = 27/84 (32%), Positives = 43/84 (51%), Gaps = 1/84 (1%) Frame = +2 Query: 206 NVQNCFTCAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLCGPG-KCM 382 N+ CF+ N C++ G C + + Y C C PG+ G NC+ ++C+ C G C+ Sbjct: 1177 NIDECFS---NPCIH-GNCSDRVA--AYHCTCEPGYTGVNCEVDIDNCQSHQCANGATCI 1230 Query: 383 NTADSYKCACPVTYTGKNCEVKQL 454 + + Y C C +TGK C +L Sbjct: 1231 SHTNGYSCLCFGNFTGKFCRQSRL 1254 Score = 52.8 bits (121), Expect = 7e-07 Identities = 23/74 (31%), Positives = 31/74 (41%), Gaps = 1/74 (1%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLCGPGKCMNTADSYK- 403 C N C + C E ++C C PG+ G C+ SC C G + Y Sbjct: 74 CFSNPCQGSATCVNTPGERSFLCKCPPGYSGTICETTIGSCGKNSCQHGGICHQDPIYPV 133 Query: 404 CACPVTYTGKNCEV 445 C CP Y G+ CE+ Sbjct: 134 CICPAGYAGRFCEI 147 Score = 52.8 bits (121), Expect = 7e-07 Identities = 27/79 (34%), Positives = 38/79 (48%), Gaps = 2/79 (2%) Frame = +2 Query: 215 NCFTCAPNLCLNNGVCQEALTEHGYVCLCA-PGFGGNNCDRIGESCRPGLC-GPGKCMNT 388 N CA CL+ G+C + E+ Y C C GF G +C+ + C C C ++ Sbjct: 262 NTDECASQPCLHGGLCVDG--ENRYSCNCTGSGFTGTHCETLMPLCWSKPCHNNATCEDS 319 Query: 389 ADSYKCACPVTYTGKNCEV 445 D+Y C C YTG CE+ Sbjct: 320 VDNYTCHCWPGYTGAQCEI 338 Score = 51.6 bits (118), Expect = 2e-06 Identities = 23/77 (29%), Positives = 38/77 (49%), Gaps = 2/77 (2%) Frame = +2 Query: 224 TCAPNLCLNNGVC-QEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLCGPGK-CMNTADS 397 +C N C + G+C Q+ + VC+C G+ G C+ + C C G C + D Sbjct: 113 SCGKNSCQHGGICHQDPIYP---VCICPAGYAGRFCEIDHDECASSPCQNGAVCQDGIDG 169 Query: 398 YKCACPVTYTGKNCEVK 448 Y C C Y G++C+++ Sbjct: 170 YSCFCVPGYQGRHCDLE 186 Score = 47.2 bits (107), Expect = 4e-05 Identities = 19/45 (42%), Positives = 23/45 (51%), Gaps = 1/45 (2%) Frame = +2 Query: 284 GYVCLCAPGFGGNNCDRIGESCRPGLC-GPGKCMNTADSYKCACP 415 GYVC+C PGF G +C+ C C G C N +Y C CP Sbjct: 380 GYVCICQPGFTGIHCEEDVNECSSNPCQNGGTCENLPGNYTCHCP 424 Score = 46.8 bits (106), Expect = 5e-05 Identities = 24/80 (30%), Positives = 35/80 (43%), Gaps = 3/80 (3%) Frame = +2 Query: 212 QNCFTCAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLC-GPGKCMNT 388 +N C N C NN C++ ++ C +CD + + C C G C+NT Sbjct: 29 KNNTRCLSNSCQNNSTCKDFSKDNDCSCSDTANNLDKDCDNMKDPCFSNPCQGSATCVNT 88 Query: 389 AD--SYKCACPVTYTGKNCE 442 S+ C CP Y+G CE Sbjct: 89 PGERSFLCKCPPGYSGTICE 108 Score = 45.2 bits (102), Expect = 1e-04 Identities = 24/75 (32%), Positives = 34/75 (45%), Gaps = 2/75 (2%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHG-YVCLCAPGFGGNNCDRIGESCRPGLCGPG-KCMNTADSY 400 CA + C N C L E G Y C+C + G NC+ + C C G C + +Y Sbjct: 190 CASDPCKNEATC---LNEIGRYTCICPHNYSGVNCELEIDECWSQPCLNGATCQDALGAY 246 Query: 401 KCACPVTYTGKNCEV 445 C C + G +CE+ Sbjct: 247 FCDCAPGFLGDHCEL 261 Score = 42.7 bits (96), Expect = 8e-04 Identities = 38/151 (25%), Positives = 61/151 (40%), Gaps = 12/151 (7%) Frame = +2 Query: 29 SPDQWTVLELNQPLYIGGVPDFDQLPIDLAGASGFVGCISMLILGNEE-------KNIMA 187 S W + E +YIGG+PD + ++ F GCI + L N+ N + Sbjct: 818 SASTWKI-EKGDVIYIGGLPDKQETELN---GGFFKGCIQDVRLNNQNLEFFPNPTNNAS 873 Query: 188 LALEKENV-QNCF---TCAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRP 355 L NV Q C +C N C N GVC + + C C G C+ + + C Sbjct: 874 LNPVLVNVTQGCAGDNSCKSNPCHNGGVCHSRWDD--FSCSCPALTSGKACEEV-QWCGF 930 Query: 356 GLCGPG-KCMNTADSYKCACPVTYTGKNCEV 445 C G +C ++C + G++ ++ Sbjct: 931 SPCPHGAQCQPVLQGFECIANAVFNGQSGQI 961 Score = 40.7 bits (91), Expect = 0.003 Identities = 24/88 (27%), Positives = 35/88 (39%), Gaps = 9/88 (10%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVC----LCAPGFGGNNCDRIGESCRPGLC-GPGKCM--- 382 C+ N C N G C+ + C L +GG +C I C C G C+ Sbjct: 401 CSSNPCQNGGTCENLPGNYTCHCPFDNLSRTFYGGRDCSDILLGCTHQQCLNNGTCIPHF 460 Query: 383 -NTADSYKCACPVTYTGKNCEVKQLIEY 463 + + C CP YTG CE+ + + Sbjct: 461 QDGQHGFSCLCPSGYTGSLCEIATTLSF 488 Score = 37.1 bits (82), Expect = 0.039 Identities = 14/35 (40%), Positives = 21/35 (60%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCD 331 CA + C+N G+CQ+ L + + CLC F G C+ Sbjct: 1301 CASDPCVNGGLCQDLLNK--FQCLCDVAFAGERCE 1333 Score = 35.5 bits (78), Expect = 0.12 Identities = 22/89 (24%), Positives = 35/89 (39%), Gaps = 5/89 (5%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLC-GPGKCMNTADSYK 403 C C NN C++++ Y C C PG+ G C+ C C G+C+ + + Sbjct: 305 CWSKPCHNNATCEDSVDN--YTCHCWPGYTGAQCEIDLNECNSNPCQSNGECVELSSEKQ 362 Query: 404 ----CACPVTYTGKNCEVKQLIEYPAFTG 478 P +++ I P FTG Sbjct: 363 YGRITGLPSSFSYHEASGYVCICQPGFTG 391 Score = 33.1 bits (72), Expect = 0.63 Identities = 14/37 (37%), Positives = 19/37 (51%), Gaps = 1/37 (2%) Frame = +2 Query: 344 SCRPGLC-GPGKCMNTADSYKCACPVTYTGKNCEVKQ 451 SC+ C G C + D + C+CP +GK CE Q Sbjct: 890 SCKSNPCHNGGVCHSRWDDFSCSCPALTSGKACEEVQ 926 Score = 29.9 bits (64), Expect = 5.9 Identities = 11/23 (47%), Positives = 14/23 (60%) Frame = +2 Query: 371 GKCMNTADSYKCACPVTYTGKNC 439 G+C+N SY+C C Y G NC Sbjct: 685 GRCINLWLSYQCDCHRPYEGPNC 707 >AL136322-3|CAI16646.1| 1406|Homo sapiens crumbs homolog 1 (Drosophila) protein. Length = 1406 Score = 69.7 bits (163), Expect = 6e-12 Identities = 29/75 (38%), Positives = 39/75 (52%), Gaps = 1/75 (1%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLC-GPGKCMNTADSYK 403 CA + C N VCQ+ + GY C C PG+ G +CD + C C C+N Y Sbjct: 152 CASSPCQNGAVCQDGID--GYSCFCVPGYQGRHCDLEVDECASDPCKNEATCLNEIGRYT 209 Query: 404 CACPVTYTGKNCEVK 448 C CP Y+G NCE++ Sbjct: 210 CICPHNYSGVNCELE 224 Score = 58.8 bits (136), Expect = 1e-08 Identities = 26/73 (35%), Positives = 36/73 (49%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLCGPGKCMNTADSYKC 406 C N CL+ G C++ + Y C C G+ G +C+ + C C G C + +Y C Sbjct: 1143 CNSNPCLHGGNCEDIYSS--YHCSCPLGWSGKHCELNIDECFSNPCIHGNCSDRVAAYHC 1200 Query: 407 ACPVTYTGKNCEV 445 C YTG NCEV Sbjct: 1201 TCEPGYTGVNCEV 1213 Score = 56.4 bits (130), Expect = 6e-08 Identities = 25/69 (36%), Positives = 35/69 (50%), Gaps = 1/69 (1%) Frame = +2 Query: 242 CLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLC-GPGKCMNTADSYKCACPV 418 C N G C E TE C+C PGF G C++ + C C G C + + ++C C V Sbjct: 1268 CYNGGNCTEFQTE--LKCMCRPGFTGEWCEKDIDECASDPCVNGGLCQDLLNKFQCLCDV 1325 Query: 419 TYTGKNCEV 445 + G+ CEV Sbjct: 1326 AFAGERCEV 1334 Score = 56.0 bits (129), Expect = 8e-08 Identities = 30/75 (40%), Positives = 42/75 (56%), Gaps = 3/75 (4%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESC--RPGLCGPGKCMNTADSY 400 C CLN CQ+AL Y C CAPGF G++C+ + C +P L G G C++ + Y Sbjct: 228 CWSQPCLNGATCQDALG--AYFCDCAPGFLGDHCELNTDECASQPCLHG-GLCVDGENRY 284 Query: 401 KCACPVT-YTGKNCE 442 C C + +TG +CE Sbjct: 285 SCNCTGSGFTGTHCE 299 Score = 53.6 bits (123), Expect = 4e-07 Identities = 27/84 (32%), Positives = 43/84 (51%), Gaps = 1/84 (1%) Frame = +2 Query: 206 NVQNCFTCAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLCGPG-KCM 382 N+ CF+ N C++ G C + + Y C C PG+ G NC+ ++C+ C G C+ Sbjct: 1177 NIDECFS---NPCIH-GNCSDRVA--AYHCTCEPGYTGVNCEVDIDNCQSHQCANGATCI 1230 Query: 383 NTADSYKCACPVTYTGKNCEVKQL 454 + + Y C C +TGK C +L Sbjct: 1231 SHTNGYSCLCFGNFTGKFCRQSRL 1254 Score = 52.8 bits (121), Expect = 7e-07 Identities = 23/74 (31%), Positives = 31/74 (41%), Gaps = 1/74 (1%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLCGPGKCMNTADSYK- 403 C N C + C E ++C C PG+ G C+ SC C G + Y Sbjct: 74 CFSNPCQGSATCVNTPGERSFLCKCPPGYSGTICETTIGSCGKNSCQHGGICHQDPIYPV 133 Query: 404 CACPVTYTGKNCEV 445 C CP Y G+ CE+ Sbjct: 134 CICPAGYAGRFCEI 147 Score = 52.8 bits (121), Expect = 7e-07 Identities = 27/79 (34%), Positives = 38/79 (48%), Gaps = 2/79 (2%) Frame = +2 Query: 215 NCFTCAPNLCLNNGVCQEALTEHGYVCLCA-PGFGGNNCDRIGESCRPGLC-GPGKCMNT 388 N CA CL+ G+C + E+ Y C C GF G +C+ + C C C ++ Sbjct: 262 NTDECASQPCLHGGLCVDG--ENRYSCNCTGSGFTGTHCETLMPLCWSKPCHNNATCEDS 319 Query: 389 ADSYKCACPVTYTGKNCEV 445 D+Y C C YTG CE+ Sbjct: 320 VDNYTCHCWPGYTGAQCEI 338 Score = 51.6 bits (118), Expect = 2e-06 Identities = 23/77 (29%), Positives = 38/77 (49%), Gaps = 2/77 (2%) Frame = +2 Query: 224 TCAPNLCLNNGVC-QEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLCGPGK-CMNTADS 397 +C N C + G+C Q+ + VC+C G+ G C+ + C C G C + D Sbjct: 113 SCGKNSCQHGGICHQDPIYP---VCICPAGYAGRFCEIDHDECASSPCQNGAVCQDGIDG 169 Query: 398 YKCACPVTYTGKNCEVK 448 Y C C Y G++C+++ Sbjct: 170 YSCFCVPGYQGRHCDLE 186 Score = 47.2 bits (107), Expect = 4e-05 Identities = 19/45 (42%), Positives = 23/45 (51%), Gaps = 1/45 (2%) Frame = +2 Query: 284 GYVCLCAPGFGGNNCDRIGESCRPGLC-GPGKCMNTADSYKCACP 415 GYVC+C PGF G +C+ C C G C N +Y C CP Sbjct: 380 GYVCICQPGFTGIHCEEDVNECSSNPCQNGGTCENLPGNYTCHCP 424 Score = 46.8 bits (106), Expect = 5e-05 Identities = 24/80 (30%), Positives = 35/80 (43%), Gaps = 3/80 (3%) Frame = +2 Query: 212 QNCFTCAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLC-GPGKCMNT 388 +N C N C NN C++ ++ C +CD + + C C G C+NT Sbjct: 29 KNNTRCLSNSCQNNSTCKDFSKDNDCSCSDTANNLDKDCDNMKDPCFSNPCQGSATCVNT 88 Query: 389 AD--SYKCACPVTYTGKNCE 442 S+ C CP Y+G CE Sbjct: 89 PGERSFLCKCPPGYSGTICE 108 Score = 45.2 bits (102), Expect = 1e-04 Identities = 24/75 (32%), Positives = 34/75 (45%), Gaps = 2/75 (2%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHG-YVCLCAPGFGGNNCDRIGESCRPGLCGPG-KCMNTADSY 400 CA + C N C L E G Y C+C + G NC+ + C C G C + +Y Sbjct: 190 CASDPCKNEATC---LNEIGRYTCICPHNYSGVNCELEIDECWSQPCLNGATCQDALGAY 246 Query: 401 KCACPVTYTGKNCEV 445 C C + G +CE+ Sbjct: 247 FCDCAPGFLGDHCEL 261 Score = 42.7 bits (96), Expect = 8e-04 Identities = 38/151 (25%), Positives = 61/151 (40%), Gaps = 12/151 (7%) Frame = +2 Query: 29 SPDQWTVLELNQPLYIGGVPDFDQLPIDLAGASGFVGCISMLILGNEE-------KNIMA 187 S W + E +YIGG+PD + ++ F GCI + L N+ N + Sbjct: 818 SASTWKI-EKGDVIYIGGLPDKQETELN---GGFFKGCIQDVRLNNQNLEFFPNPTNNAS 873 Query: 188 LALEKENV-QNCF---TCAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRP 355 L NV Q C +C N C N GVC + + C C G C+ + + C Sbjct: 874 LNPVLVNVTQGCAGDNSCKSNPCHNGGVCHSRWDD--FSCSCPALTSGKACEEV-QWCGF 930 Query: 356 GLCGPG-KCMNTADSYKCACPVTYTGKNCEV 445 C G +C ++C + G++ ++ Sbjct: 931 SPCPHGAQCQPVLQGFECIANAVFNGQSGQI 961 Score = 40.7 bits (91), Expect = 0.003 Identities = 24/88 (27%), Positives = 35/88 (39%), Gaps = 9/88 (10%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVC----LCAPGFGGNNCDRIGESCRPGLC-GPGKCM--- 382 C+ N C N G C+ + C L +GG +C I C C G C+ Sbjct: 401 CSSNPCQNGGTCENLPGNYTCHCPFDNLSRTFYGGRDCSDILLGCTHQQCLNNGTCIPHF 460 Query: 383 -NTADSYKCACPVTYTGKNCEVKQLIEY 463 + + C CP YTG CE+ + + Sbjct: 461 QDGQHGFSCLCPSGYTGSLCEIATTLSF 488 Score = 37.1 bits (82), Expect = 0.039 Identities = 14/35 (40%), Positives = 21/35 (60%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCD 331 CA + C+N G+CQ+ L + + CLC F G C+ Sbjct: 1301 CASDPCVNGGLCQDLLNK--FQCLCDVAFAGERCE 1333 Score = 35.5 bits (78), Expect = 0.12 Identities = 22/89 (24%), Positives = 35/89 (39%), Gaps = 5/89 (5%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLC-GPGKCMNTADSYK 403 C C NN C++++ Y C C PG+ G C+ C C G+C+ + + Sbjct: 305 CWSKPCHNNATCEDSVDN--YTCHCWPGYTGAQCEIDLNECNSNPCQSNGECVELSSEKQ 362 Query: 404 ----CACPVTYTGKNCEVKQLIEYPAFTG 478 P +++ I P FTG Sbjct: 363 YGRITGLPSSFSYHEASGYVCICQPGFTG 391 Score = 33.1 bits (72), Expect = 0.63 Identities = 14/37 (37%), Positives = 19/37 (51%), Gaps = 1/37 (2%) Frame = +2 Query: 344 SCRPGLC-GPGKCMNTADSYKCACPVTYTGKNCEVKQ 451 SC+ C G C + D + C+CP +GK CE Q Sbjct: 890 SCKSNPCHNGGVCHSRWDDFSCSCPALTSGKACEEVQ 926 Score = 29.9 bits (64), Expect = 5.9 Identities = 11/23 (47%), Positives = 14/23 (60%) Frame = +2 Query: 371 GKCMNTADSYKCACPVTYTGKNC 439 G+C+N SY+C C Y G NC Sbjct: 685 GRCINLWLSYQCDCHRPYEGPNC 707 >AF154671-1|AAF01361.1| 1376|Homo sapiens CRB1 protein. Length = 1376 Score = 69.7 bits (163), Expect = 6e-12 Identities = 29/75 (38%), Positives = 39/75 (52%), Gaps = 1/75 (1%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLC-GPGKCMNTADSYK 403 CA + C N VCQ+ + GY C C PG+ G +CD + C C C+N Y Sbjct: 152 CASSPCQNGAVCQDGID--GYSCFCVPGYQGRHCDLEVDECASDPCKNEATCLNEIGRYT 209 Query: 404 CACPVTYTGKNCEVK 448 C CP Y+G NCE++ Sbjct: 210 CICPHNYSGVNCELE 224 Score = 58.8 bits (136), Expect = 1e-08 Identities = 26/73 (35%), Positives = 36/73 (49%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLCGPGKCMNTADSYKC 406 C N CL+ G C++ + Y C C G+ G +C+ + C C G C + +Y C Sbjct: 1143 CNSNPCLHGGNCEDIYSS--YHCSCPLGWSGKHCELNIDECFSNPCIHGNCSDRVAAYHC 1200 Query: 407 ACPVTYTGKNCEV 445 C YTG NCEV Sbjct: 1201 TCEPGYTGVNCEV 1213 Score = 56.4 bits (130), Expect = 6e-08 Identities = 25/69 (36%), Positives = 35/69 (50%), Gaps = 1/69 (1%) Frame = +2 Query: 242 CLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLC-GPGKCMNTADSYKCACPV 418 C N G C E TE C+C PGF G C++ + C C G C + + ++C C V Sbjct: 1268 CYNGGNCTEFQTE--LKCMCRPGFTGEWCEKDIDECASDPCVNGGLCQDLLNKFQCLCDV 1325 Query: 419 TYTGKNCEV 445 + G+ CEV Sbjct: 1326 AFAGERCEV 1334 Score = 56.0 bits (129), Expect = 8e-08 Identities = 30/75 (40%), Positives = 42/75 (56%), Gaps = 3/75 (4%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESC--RPGLCGPGKCMNTADSY 400 C CLN CQ+AL Y C CAPGF G++C+ + C +P L G G C++ + Y Sbjct: 228 CWSQPCLNGATCQDALG--AYFCDCAPGFLGDHCELNTDECASQPCLHG-GLCVDGENRY 284 Query: 401 KCACPVT-YTGKNCE 442 C C + +TG +CE Sbjct: 285 SCNCTGSGFTGTHCE 299 Score = 53.6 bits (123), Expect = 4e-07 Identities = 27/84 (32%), Positives = 43/84 (51%), Gaps = 1/84 (1%) Frame = +2 Query: 206 NVQNCFTCAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLCGPG-KCM 382 N+ CF+ N C++ G C + + Y C C PG+ G NC+ ++C+ C G C+ Sbjct: 1177 NIDECFS---NPCIH-GNCSDRVA--AYHCTCEPGYTGVNCEVDIDNCQSHQCANGATCI 1230 Query: 383 NTADSYKCACPVTYTGKNCEVKQL 454 + + Y C C +TGK C +L Sbjct: 1231 SHTNGYSCLCFGNFTGKFCRQSRL 1254 Score = 52.8 bits (121), Expect = 7e-07 Identities = 23/74 (31%), Positives = 31/74 (41%), Gaps = 1/74 (1%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLCGPGKCMNTADSYK- 403 C N C + C E ++C C PG+ G C+ SC C G + Y Sbjct: 74 CFSNPCQGSATCVNTPGERSFLCKCPPGYSGTICETTIGSCGKNSCQHGGICHQDPIYPV 133 Query: 404 CACPVTYTGKNCEV 445 C CP Y G+ CE+ Sbjct: 134 CICPAGYAGRFCEI 147 Score = 52.8 bits (121), Expect = 7e-07 Identities = 27/79 (34%), Positives = 38/79 (48%), Gaps = 2/79 (2%) Frame = +2 Query: 215 NCFTCAPNLCLNNGVCQEALTEHGYVCLCA-PGFGGNNCDRIGESCRPGLC-GPGKCMNT 388 N CA CL+ G+C + E+ Y C C GF G +C+ + C C C ++ Sbjct: 262 NTDECASQPCLHGGLCVDG--ENRYSCNCTGSGFTGTHCETLMPLCWSKPCHNNATCEDS 319 Query: 389 ADSYKCACPVTYTGKNCEV 445 D+Y C C YTG CE+ Sbjct: 320 VDNYTCHCWPGYTGAQCEI 338 Score = 51.6 bits (118), Expect = 2e-06 Identities = 23/77 (29%), Positives = 38/77 (49%), Gaps = 2/77 (2%) Frame = +2 Query: 224 TCAPNLCLNNGVC-QEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLCGPGK-CMNTADS 397 +C N C + G+C Q+ + VC+C G+ G C+ + C C G C + D Sbjct: 113 SCGKNSCQHGGICHQDPIYP---VCICPAGYAGRFCEIDHDECASSPCQNGAVCQDGIDG 169 Query: 398 YKCACPVTYTGKNCEVK 448 Y C C Y G++C+++ Sbjct: 170 YSCFCVPGYQGRHCDLE 186 Score = 47.2 bits (107), Expect = 4e-05 Identities = 19/45 (42%), Positives = 23/45 (51%), Gaps = 1/45 (2%) Frame = +2 Query: 284 GYVCLCAPGFGGNNCDRIGESCRPGLC-GPGKCMNTADSYKCACP 415 GYVC+C PGF G +C+ C C G C N +Y C CP Sbjct: 380 GYVCICQPGFTGIHCEEDVNECSSNPCQNGGTCENLPGNYTCHCP 424 Score = 46.8 bits (106), Expect = 5e-05 Identities = 24/80 (30%), Positives = 35/80 (43%), Gaps = 3/80 (3%) Frame = +2 Query: 212 QNCFTCAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLC-GPGKCMNT 388 +N C N C NN C++ ++ C +CD + + C C G C+NT Sbjct: 29 KNNTRCLSNSCQNNSTCKDFSKDNDCSCSDTANNLDKDCDNMKDPCFSNPCQGSATCVNT 88 Query: 389 AD--SYKCACPVTYTGKNCE 442 S+ C CP Y+G CE Sbjct: 89 PGERSFLCKCPPGYSGTICE 108 Score = 45.2 bits (102), Expect = 1e-04 Identities = 24/75 (32%), Positives = 34/75 (45%), Gaps = 2/75 (2%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHG-YVCLCAPGFGGNNCDRIGESCRPGLCGPG-KCMNTADSY 400 CA + C N C L E G Y C+C + G NC+ + C C G C + +Y Sbjct: 190 CASDPCKNEATC---LNEIGRYTCICPHNYSGVNCELEIDECWSQPCLNGATCQDALGAY 246 Query: 401 KCACPVTYTGKNCEV 445 C C + G +CE+ Sbjct: 247 FCDCAPGFLGDHCEL 261 Score = 42.7 bits (96), Expect = 8e-04 Identities = 38/151 (25%), Positives = 61/151 (40%), Gaps = 12/151 (7%) Frame = +2 Query: 29 SPDQWTVLELNQPLYIGGVPDFDQLPIDLAGASGFVGCISMLILGNEE-------KNIMA 187 S W + E +YIGG+PD + ++ F GCI + L N+ N + Sbjct: 818 SASTWKI-EKGDVIYIGGLPDKQETELN---GGFFKGCIQDVRLNNQNLEFFPNPTNNAS 873 Query: 188 LALEKENV-QNCF---TCAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRP 355 L NV Q C +C N C N GVC + + C C G C+ + + C Sbjct: 874 LNPVLVNVTQGCAGDNSCKSNPCHNGGVCHSRWDD--FSCSCPALTSGKACEEV-QWCGF 930 Query: 356 GLCGPG-KCMNTADSYKCACPVTYTGKNCEV 445 C G +C ++C + G++ ++ Sbjct: 931 SPCPHGAQCQPVLQGFECIANAVFNGQSGQI 961 Score = 40.7 bits (91), Expect = 0.003 Identities = 24/88 (27%), Positives = 35/88 (39%), Gaps = 9/88 (10%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVC----LCAPGFGGNNCDRIGESCRPGLC-GPGKCM--- 382 C+ N C N G C+ + C L +GG +C I C C G C+ Sbjct: 401 CSSNPCQNGGTCENLPGNYTCHCPFDNLSRTFYGGRDCSDILLGCTHQQCLNNGTCIPHF 460 Query: 383 -NTADSYKCACPVTYTGKNCEVKQLIEY 463 + + C CP YTG CE+ + + Sbjct: 461 QDGQHGFSCLCPSGYTGSLCEIATTLSF 488 Score = 37.1 bits (82), Expect = 0.039 Identities = 14/35 (40%), Positives = 21/35 (60%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCD 331 CA + C+N G+CQ+ L + + CLC F G C+ Sbjct: 1301 CASDPCVNGGLCQDLLNK--FQCLCDVAFAGERCE 1333 Score = 35.5 bits (78), Expect = 0.12 Identities = 22/89 (24%), Positives = 35/89 (39%), Gaps = 5/89 (5%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLC-GPGKCMNTADSYK 403 C C NN C++++ Y C C PG+ G C+ C C G+C+ + + Sbjct: 305 CWSKPCHNNATCEDSVDN--YTCHCWPGYTGAQCEIDLNECNSNPCQSNGECVELSSEKQ 362 Query: 404 ----CACPVTYTGKNCEVKQLIEYPAFTG 478 P +++ I P FTG Sbjct: 363 YGRITGLPSSFSYHEASGYVCICQPGFTG 391 Score = 33.1 bits (72), Expect = 0.63 Identities = 14/37 (37%), Positives = 19/37 (51%), Gaps = 1/37 (2%) Frame = +2 Query: 344 SCRPGLC-GPGKCMNTADSYKCACPVTYTGKNCEVKQ 451 SC+ C G C + D + C+CP +GK CE Q Sbjct: 890 SCKSNPCHNGGVCHSRWDDFSCSCPALTSGKACEEVQ 926 Score = 29.9 bits (64), Expect = 5.9 Identities = 11/23 (47%), Positives = 14/23 (60%) Frame = +2 Query: 371 GKCMNTADSYKCACPVTYTGKNC 439 G+C+N SY+C C Y G NC Sbjct: 685 GRCINLWLSYQCDCHRPYEGPNC 707 >AB208923-1|BAD92160.1| 441|Homo sapiens crumbs homolog 1 isoform II precursor variant protein. Length = 441 Score = 69.7 bits (163), Expect = 6e-12 Identities = 29/75 (38%), Positives = 39/75 (52%), Gaps = 1/75 (1%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLC-GPGKCMNTADSYK 403 CA + C N VCQ+ + GY C C PG+ G +CD + C C C+N Y Sbjct: 177 CASSPCQNGAVCQDGID--GYSCFCVPGYQGRHCDLEVDECASDPCKNEATCLNEIGRYT 234 Query: 404 CACPVTYTGKNCEVK 448 C CP Y+G NCE++ Sbjct: 235 CICPHNYSGVNCELE 249 Score = 56.0 bits (129), Expect = 8e-08 Identities = 30/75 (40%), Positives = 42/75 (56%), Gaps = 3/75 (4%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESC--RPGLCGPGKCMNTADSY 400 C CLN CQ+AL Y C CAPGF G++C+ + C +P L G G C++ + Y Sbjct: 253 CWSQPCLNGATCQDALG--AYFCDCAPGFLGDHCELNTDECASQPCLHG-GLCVDGENRY 309 Query: 401 KCACPVT-YTGKNCE 442 C C + +TG +CE Sbjct: 310 SCNCTGSGFTGTHCE 324 Score = 52.8 bits (121), Expect = 7e-07 Identities = 23/74 (31%), Positives = 31/74 (41%), Gaps = 1/74 (1%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLCGPGKCMNTADSYK- 403 C N C + C E ++C C PG+ G C+ SC C G + Y Sbjct: 99 CFSNPCQGSATCVNTPGERSFLCKCPPGYSGTICETTIGSCGKNSCQHGGICHQDPIYPV 158 Query: 404 CACPVTYTGKNCEV 445 C CP Y G+ CE+ Sbjct: 159 CICPAGYAGRFCEI 172 Score = 52.8 bits (121), Expect = 7e-07 Identities = 27/79 (34%), Positives = 38/79 (48%), Gaps = 2/79 (2%) Frame = +2 Query: 215 NCFTCAPNLCLNNGVCQEALTEHGYVCLCA-PGFGGNNCDRIGESCRPGLC-GPGKCMNT 388 N CA CL+ G+C + E+ Y C C GF G +C+ + C C C ++ Sbjct: 287 NTDECASQPCLHGGLCVDG--ENRYSCNCTGSGFTGTHCETLMPLCWSKPCHNNATCEDS 344 Query: 389 ADSYKCACPVTYTGKNCEV 445 D+Y C C YTG CE+ Sbjct: 345 VDNYTCHCWPGYTGAQCEI 363 Score = 51.6 bits (118), Expect = 2e-06 Identities = 23/77 (29%), Positives = 38/77 (49%), Gaps = 2/77 (2%) Frame = +2 Query: 224 TCAPNLCLNNGVC-QEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLCGPGK-CMNTADS 397 +C N C + G+C Q+ + VC+C G+ G C+ + C C G C + D Sbjct: 138 SCGKNSCQHGGICHQDPIYP---VCICPAGYAGRFCEIDHDECASSPCQNGAVCQDGIDG 194 Query: 398 YKCACPVTYTGKNCEVK 448 Y C C Y G++C+++ Sbjct: 195 YSCFCVPGYQGRHCDLE 211 Score = 46.8 bits (106), Expect = 5e-05 Identities = 24/80 (30%), Positives = 35/80 (43%), Gaps = 3/80 (3%) Frame = +2 Query: 212 QNCFTCAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLC-GPGKCMNT 388 +N C N C NN C++ ++ C +CD + + C C G C+NT Sbjct: 54 KNNTRCLSNSCQNNSTCKDFSKDNDCSCSDTANNLDKDCDNMKDPCFSNPCQGSATCVNT 113 Query: 389 AD--SYKCACPVTYTGKNCE 442 S+ C CP Y+G CE Sbjct: 114 PGERSFLCKCPPGYSGTICE 133 Score = 45.2 bits (102), Expect = 1e-04 Identities = 24/75 (32%), Positives = 34/75 (45%), Gaps = 2/75 (2%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHG-YVCLCAPGFGGNNCDRIGESCRPGLCGPG-KCMNTADSY 400 CA + C N C L E G Y C+C + G NC+ + C C G C + +Y Sbjct: 215 CASDPCKNEATC---LNEIGRYTCICPHNYSGVNCELEIDECWSQPCLNGATCQDALGAY 271 Query: 401 KCACPVTYTGKNCEV 445 C C + G +CE+ Sbjct: 272 FCDCAPGFLGDHCEL 286 Score = 37.1 bits (82), Expect = 0.039 Identities = 23/91 (25%), Positives = 36/91 (39%), Gaps = 5/91 (5%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLC-GPGKCMNTADSYK 403 C C NN C++++ Y C C PG+ G C+ C C G+C+ + + Sbjct: 330 CWSKPCHNNATCEDSVDN--YTCHCWPGYTGAQCEIDLNECNSNPCQSNGECVELSSEKQ 387 Query: 404 ----CACPVTYTGKNCEVKQLIEYPAFTGSA 484 P +++ I P FTG A Sbjct: 388 YGRITGLPSSFSYHEASGYVCICQPGFTGEA 418 >AY358892-1|AAQ89251.1| 723|Homo sapiens DLL1 protein. Length = 723 Score = 69.3 bits (162), Expect = 8e-12 Identities = 32/76 (42%), Positives = 41/76 (53%), Gaps = 2/76 (2%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLC-GPGKCMNTAD-SY 400 C P+ C N G C + E+ Y C C PGF G C+ +C G C G+C ++ D Y Sbjct: 332 CDPSPCKNGGSCTDL--ENSYSCTCPPGFYGKICELSAMTCADGPCFNGGRCSDSPDGGY 389 Query: 401 KCACPVTYTGKNCEVK 448 C CPV Y+G NCE K Sbjct: 390 SCRCPVGYSGFNCEKK 405 Score = 65.3 bits (152), Expect = 1e-10 Identities = 26/77 (33%), Positives = 42/77 (54%), Gaps = 1/77 (1%) Frame = +2 Query: 215 NCFTCAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLCGPG-KCMNTA 391 + TCA C N G C ++ + GY C C G+ G NC++ + C C G KC++ Sbjct: 366 SAMTCADGPCFNGGRCSDS-PDGGYSCRCPVGYSGFNCEKKIDYCSSSPCSNGAKCVDLG 424 Query: 392 DSYKCACPVTYTGKNCE 442 D+Y C C ++G++C+ Sbjct: 425 DAYLCRCQAGFSGRHCD 441 Score = 57.6 bits (133), Expect = 3e-08 Identities = 27/82 (32%), Positives = 37/82 (45%), Gaps = 3/82 (3%) Frame = +2 Query: 242 CLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLC-GPGKCMNTADSYKCACPV 418 C N C + Y C C PG+ G C+ + C P C G C + +SY C CP Sbjct: 298 CKNGATCTNT-GQGSYTCSCRPGYTGATCELGIDECDPSPCKNGGSCTDLENSYSCTCPP 356 Query: 419 TYTGKNCEVKQL--IEYPAFTG 478 + GK CE+ + + P F G Sbjct: 357 GFYGKICELSAMTCADGPCFNG 378 Score = 57.2 bits (132), Expect = 3e-08 Identities = 24/72 (33%), Positives = 34/72 (47%), Gaps = 1/72 (1%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLCGPG-KCMNTADSYK 403 C+ + C N C + Y+C C GF G +CD + C C G C + + + Sbjct: 409 CSSSPCSNGAKCVDL--GDAYLCRCQAGFSGRHCDDNVDDCASSPCANGGTCRDGVNDFS 466 Query: 404 CACPVTYTGKNC 439 C CP YTG+NC Sbjct: 467 CTCPPGYTGRNC 478 Score = 55.2 bits (127), Expect = 1e-07 Identities = 25/77 (32%), Positives = 33/77 (42%), Gaps = 1/77 (1%) Frame = +2 Query: 215 NCFTCAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLCGPG-KCMNTA 391 N CA + C N G C++ + + + C C PG+ G NC C C G C Sbjct: 443 NVDDCASSPCANGGTCRDGVND--FSCTCPPGYTGRNCSAPVSRCEHAPCHNGATCHERG 500 Query: 392 DSYKCACPVTYTGKNCE 442 Y C C Y G NC+ Sbjct: 501 HRYVCECARGYGGPNCQ 517 Score = 40.3 bits (90), Expect = 0.004 Identities = 23/71 (32%), Positives = 31/71 (43%), Gaps = 3/71 (4%) Frame = +2 Query: 242 CLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESC-RPGLCGPG-KCMNTAD-SYKCAC 412 C+ C + + C C G+GG C++ C C G C NT SY C+C Sbjct: 257 CIRYPGCLHGTCQQPWQCNCQEGWGGLFCNQDLNYCTHHKPCKNGATCTNTGQGSYTCSC 316 Query: 413 PVTYTGKNCEV 445 YTG CE+ Sbjct: 317 RPGYTGATCEL 327 Score = 37.5 bits (83), Expect = 0.029 Identities = 18/44 (40%), Positives = 20/44 (45%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPG 358 C C N C E H YVC CA G+GG NC + PG Sbjct: 485 CEHAPCHNGATCHER--GHRYVCECARGYGGPNCQFLLPELPPG 526 >AL078605-2|CAB89569.1| 723|Homo sapiens delta-like 1 (Drosophila) protein. Length = 723 Score = 69.3 bits (162), Expect = 8e-12 Identities = 32/76 (42%), Positives = 41/76 (53%), Gaps = 2/76 (2%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLC-GPGKCMNTAD-SY 400 C P+ C N G C + E+ Y C C PGF G C+ +C G C G+C ++ D Y Sbjct: 332 CDPSPCKNGGSCTDL--ENSYSCTCPPGFYGKICELSAMTCADGPCFNGGRCSDSPDGGY 389 Query: 401 KCACPVTYTGKNCEVK 448 C CPV Y+G NCE K Sbjct: 390 SCRCPVGYSGFNCEKK 405 Score = 65.3 bits (152), Expect = 1e-10 Identities = 26/77 (33%), Positives = 42/77 (54%), Gaps = 1/77 (1%) Frame = +2 Query: 215 NCFTCAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLCGPG-KCMNTA 391 + TCA C N G C ++ + GY C C G+ G NC++ + C C G KC++ Sbjct: 366 SAMTCADGPCFNGGRCSDS-PDGGYSCRCPVGYSGFNCEKKIDYCSSSPCSNGAKCVDLG 424 Query: 392 DSYKCACPVTYTGKNCE 442 D+Y C C ++G++C+ Sbjct: 425 DAYLCRCQAGFSGRHCD 441 Score = 57.6 bits (133), Expect = 3e-08 Identities = 27/82 (32%), Positives = 37/82 (45%), Gaps = 3/82 (3%) Frame = +2 Query: 242 CLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLC-GPGKCMNTADSYKCACPV 418 C N C + Y C C PG+ G C+ + C P C G C + +SY C CP Sbjct: 298 CKNGATCTNT-GQGSYTCSCRPGYTGATCELGIDECDPSPCKNGGSCTDLENSYSCTCPP 356 Query: 419 TYTGKNCEVKQL--IEYPAFTG 478 + GK CE+ + + P F G Sbjct: 357 GFYGKICELSAMTCADGPCFNG 378 Score = 57.2 bits (132), Expect = 3e-08 Identities = 24/72 (33%), Positives = 34/72 (47%), Gaps = 1/72 (1%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLCGPG-KCMNTADSYK 403 C+ + C N C + Y+C C GF G +CD + C C G C + + + Sbjct: 409 CSSSPCSNGAKCVDL--GDAYLCRCQAGFSGRHCDDNVDDCASSPCANGGTCRDGVNDFS 466 Query: 404 CACPVTYTGKNC 439 C CP YTG+NC Sbjct: 467 CTCPPGYTGRNC 478 Score = 55.2 bits (127), Expect = 1e-07 Identities = 25/77 (32%), Positives = 33/77 (42%), Gaps = 1/77 (1%) Frame = +2 Query: 215 NCFTCAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLCGPG-KCMNTA 391 N CA + C N G C++ + + + C C PG+ G NC C C G C Sbjct: 443 NVDDCASSPCANGGTCRDGVND--FSCTCPPGYTGRNCSAPVSRCEHAPCHNGATCHERG 500 Query: 392 DSYKCACPVTYTGKNCE 442 Y C C Y G NC+ Sbjct: 501 HRYVCECARGYGGPNCQ 517 Score = 40.3 bits (90), Expect = 0.004 Identities = 23/71 (32%), Positives = 31/71 (43%), Gaps = 3/71 (4%) Frame = +2 Query: 242 CLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESC-RPGLCGPG-KCMNTAD-SYKCAC 412 C+ C + + C C G+GG C++ C C G C NT SY C+C Sbjct: 257 CIRYPGCLHGTCQQPWQCNCQEGWGGLFCNQDLNYCTHHKPCKNGATCTNTGQGSYTCSC 316 Query: 413 PVTYTGKNCEV 445 YTG CE+ Sbjct: 317 RPGYTGATCEL 327 Score = 37.5 bits (83), Expect = 0.029 Identities = 18/44 (40%), Positives = 20/44 (45%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPG 358 C C N C E H YVC CA G+GG NC + PG Sbjct: 485 CEHAPCHNGATCHER--GHRYVCECARGYGGPNCQFLLPELPPG 526 >AF222310-1|AAG09716.1| 723|Homo sapiens Delta1 protein. Length = 723 Score = 69.3 bits (162), Expect = 8e-12 Identities = 32/76 (42%), Positives = 41/76 (53%), Gaps = 2/76 (2%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLC-GPGKCMNTAD-SY 400 C P+ C N G C + E+ Y C C PGF G C+ +C G C G+C ++ D Y Sbjct: 332 CDPSPCKNGGSCTDL--ENSYSCTCPPGFYGKICELSAMTCADGPCFNGGRCSDSPDGGY 389 Query: 401 KCACPVTYTGKNCEVK 448 C CPV Y+G NCE K Sbjct: 390 SCRCPVGYSGFNCEKK 405 Score = 65.3 bits (152), Expect = 1e-10 Identities = 26/77 (33%), Positives = 42/77 (54%), Gaps = 1/77 (1%) Frame = +2 Query: 215 NCFTCAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLCGPG-KCMNTA 391 + TCA C N G C ++ + GY C C G+ G NC++ + C C G KC++ Sbjct: 366 SAMTCADGPCFNGGRCSDS-PDGGYSCRCPVGYSGFNCEKKIDYCSSSPCSNGAKCVDLG 424 Query: 392 DSYKCACPVTYTGKNCE 442 D+Y C C ++G++C+ Sbjct: 425 DAYLCRCQAGFSGRHCD 441 Score = 57.6 bits (133), Expect = 3e-08 Identities = 27/82 (32%), Positives = 37/82 (45%), Gaps = 3/82 (3%) Frame = +2 Query: 242 CLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLC-GPGKCMNTADSYKCACPV 418 C N C + Y C C PG+ G C+ + C P C G C + +SY C CP Sbjct: 298 CKNGATCTNT-GQGSYTCSCRPGYTGATCELGIDECDPSPCKNGGSCTDLENSYSCTCPP 356 Query: 419 TYTGKNCEVKQL--IEYPAFTG 478 + GK CE+ + + P F G Sbjct: 357 GFYGKICELSAMTCADGPCFNG 378 Score = 57.2 bits (132), Expect = 3e-08 Identities = 24/72 (33%), Positives = 34/72 (47%), Gaps = 1/72 (1%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLCGPG-KCMNTADSYK 403 C+ + C N C + Y+C C GF G +CD + C C G C + + + Sbjct: 409 CSSSPCSNGAKCVDL--GDAYLCRCQAGFSGRHCDDNVDDCASSPCANGGTCRDGVNDFS 466 Query: 404 CACPVTYTGKNC 439 C CP YTG+NC Sbjct: 467 CTCPPGYTGRNC 478 Score = 55.6 bits (128), Expect = 1e-07 Identities = 25/77 (32%), Positives = 33/77 (42%), Gaps = 1/77 (1%) Frame = +2 Query: 215 NCFTCAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLCGPG-KCMNTA 391 N CA + C N G C++ + + + C C PG+ G NC C C G C Sbjct: 443 NVDDCASSPCANGGTCRDGVND--FSCTCPPGYTGRNCSAPVSRCEHAPCHNGATCHERG 500 Query: 392 DSYKCACPVTYTGKNCE 442 Y C C Y G NC+ Sbjct: 501 HGYVCECARGYGGPNCQ 517 Score = 40.7 bits (91), Expect = 0.003 Identities = 19/44 (43%), Positives = 21/44 (47%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPG 358 C C N C E HGYVC CA G+GG NC + PG Sbjct: 485 CEHAPCHNGATCHER--GHGYVCECARGYGGPNCQFLLPELPPG 526 Score = 40.3 bits (90), Expect = 0.004 Identities = 23/71 (32%), Positives = 31/71 (43%), Gaps = 3/71 (4%) Frame = +2 Query: 242 CLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESC-RPGLCGPG-KCMNTAD-SYKCAC 412 C+ C + + C C G+GG C++ C C G C NT SY C+C Sbjct: 257 CIRYPGCLHGTCQQPWQCNCQEGWGGLFCNQDLNYCTHHKPCKNGATCTNTGQGSYTCSC 316 Query: 413 PVTYTGKNCEV 445 YTG CE+ Sbjct: 317 RPGYTGATCEL 327 >AF196571-1|AAF05834.1| 723|Homo sapiens Delta-like-1 protein protein. Length = 723 Score = 69.3 bits (162), Expect = 8e-12 Identities = 32/76 (42%), Positives = 41/76 (53%), Gaps = 2/76 (2%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLC-GPGKCMNTAD-SY 400 C P+ C N G C + E+ Y C C PGF G C+ +C G C G+C ++ D Y Sbjct: 332 CDPSPCKNGGSCTDL--ENSYSCTCPPGFYGKICELSAMTCADGPCFNGGRCSDSPDGGY 389 Query: 401 KCACPVTYTGKNCEVK 448 C CPV Y+G NCE K Sbjct: 390 SCRCPVGYSGFNCEKK 405 Score = 65.3 bits (152), Expect = 1e-10 Identities = 26/77 (33%), Positives = 42/77 (54%), Gaps = 1/77 (1%) Frame = +2 Query: 215 NCFTCAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLCGPG-KCMNTA 391 + TCA C N G C ++ + GY C C G+ G NC++ + C C G KC++ Sbjct: 366 SAMTCADGPCFNGGRCSDS-PDGGYSCRCPVGYSGFNCEKKIDYCSSSPCSNGAKCVDLG 424 Query: 392 DSYKCACPVTYTGKNCE 442 D+Y C C ++G++C+ Sbjct: 425 DAYLCRCQAGFSGRHCD 441 Score = 57.6 bits (133), Expect = 3e-08 Identities = 27/82 (32%), Positives = 37/82 (45%), Gaps = 3/82 (3%) Frame = +2 Query: 242 CLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLC-GPGKCMNTADSYKCACPV 418 C N C + Y C C PG+ G C+ + C P C G C + +SY C CP Sbjct: 298 CKNGATCTNT-GQGSYTCSCRPGYTGATCELGIDECDPSPCKNGGSCTDLENSYSCTCPP 356 Query: 419 TYTGKNCEVKQL--IEYPAFTG 478 + GK CE+ + + P F G Sbjct: 357 GFYGKICELSAMTCADGPCFNG 378 Score = 57.2 bits (132), Expect = 3e-08 Identities = 24/72 (33%), Positives = 34/72 (47%), Gaps = 1/72 (1%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLCGPG-KCMNTADSYK 403 C+ + C N C + Y+C C GF G +CD + C C G C + + + Sbjct: 409 CSSSPCSNGAKCVDL--GDAYLCRCQAGFSGRHCDDNVDDCASSPCANGGTCRDGVNDFS 466 Query: 404 CACPVTYTGKNC 439 C CP YTG+NC Sbjct: 467 CTCPPGYTGRNC 478 Score = 56.8 bits (131), Expect = 5e-08 Identities = 25/77 (32%), Positives = 34/77 (44%), Gaps = 1/77 (1%) Frame = +2 Query: 215 NCFTCAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLCGPG-KCMNTA 391 N CA + C N G C++ + + + C C PG+ G NC C C G C Sbjct: 443 NVDDCASSPCANGGTCRDGVND--FSCTCPPGYTGRNCSAPVSRCEHAPCHNGATCHQRG 500 Query: 392 DSYKCACPVTYTGKNCE 442 Y C C +Y G NC+ Sbjct: 501 HGYVCECARSYGGPNCQ 517 Score = 40.3 bits (90), Expect = 0.004 Identities = 23/71 (32%), Positives = 31/71 (43%), Gaps = 3/71 (4%) Frame = +2 Query: 242 CLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESC-RPGLCGPG-KCMNTAD-SYKCAC 412 C+ C + + C C G+GG C++ C C G C NT SY C+C Sbjct: 257 CIRYPGCLHGTCQQPWQCNCQEGWGGLFCNQDLNYCTHHKPCKNGATCTNTGQGSYTCSC 316 Query: 413 PVTYTGKNCEV 445 YTG CE+ Sbjct: 317 RPGYTGATCEL 327 Score = 37.1 bits (82), Expect = 0.039 Identities = 17/44 (38%), Positives = 20/44 (45%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPG 358 C C N C + HGYVC CA +GG NC + PG Sbjct: 485 CEHAPCHNGATCHQR--GHGYVCECARSYGGPNCQFLLPELPPG 526 >AF003522-1|AAB61286.1| 723|Homo sapiens Delta protein. Length = 723 Score = 69.3 bits (162), Expect = 8e-12 Identities = 32/76 (42%), Positives = 41/76 (53%), Gaps = 2/76 (2%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLC-GPGKCMNTAD-SY 400 C P+ C N G C + E+ Y C C PGF G C+ +C G C G+C ++ D Y Sbjct: 332 CDPSPCKNGGSCTDL--ENSYSCTCPPGFYGKICELSAMTCADGPCFNGGRCSDSPDGGY 389 Query: 401 KCACPVTYTGKNCEVK 448 C CPV Y+G NCE K Sbjct: 390 SCRCPVGYSGFNCEKK 405 Score = 65.3 bits (152), Expect = 1e-10 Identities = 26/77 (33%), Positives = 42/77 (54%), Gaps = 1/77 (1%) Frame = +2 Query: 215 NCFTCAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLCGPG-KCMNTA 391 + TCA C N G C ++ + GY C C G+ G NC++ + C C G KC++ Sbjct: 366 SAMTCADGPCFNGGRCSDS-PDGGYSCRCPVGYSGFNCEKKIDYCSSSPCSNGAKCVDLG 424 Query: 392 DSYKCACPVTYTGKNCE 442 D+Y C C ++G++C+ Sbjct: 425 DAYLCRCQAGFSGRHCD 441 Score = 57.6 bits (133), Expect = 3e-08 Identities = 27/82 (32%), Positives = 37/82 (45%), Gaps = 3/82 (3%) Frame = +2 Query: 242 CLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLC-GPGKCMNTADSYKCACPV 418 C N C + Y C C PG+ G C+ + C P C G C + +SY C CP Sbjct: 298 CKNGATCTNT-GQGSYTCSCRPGYTGATCELGIDECDPSPCKNGGSCTDLENSYSCTCPP 356 Query: 419 TYTGKNCEVKQL--IEYPAFTG 478 + GK CE+ + + P F G Sbjct: 357 GFYGKICELSAMTCADGPCFNG 378 Score = 57.2 bits (132), Expect = 3e-08 Identities = 24/72 (33%), Positives = 34/72 (47%), Gaps = 1/72 (1%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLCGPG-KCMNTADSYK 403 C+ + C N C + Y+C C GF G +CD + C C G C + + + Sbjct: 409 CSSSPCSNGAKCVDL--GDAYLCRCQAGFSGRHCDDNVDDCASSPCANGGTCRDGVNDFS 466 Query: 404 CACPVTYTGKNC 439 C CP YTG+NC Sbjct: 467 CTCPPGYTGRNC 478 Score = 55.6 bits (128), Expect = 1e-07 Identities = 25/77 (32%), Positives = 33/77 (42%), Gaps = 1/77 (1%) Frame = +2 Query: 215 NCFTCAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLCGPG-KCMNTA 391 N CA + C N G C++ + + + C C PG+ G NC C C G C Sbjct: 443 NVDDCASSPCANGGTCRDGVND--FSCTCPPGYTGRNCSAPVSRCEHAPCHNGATCHERG 500 Query: 392 DSYKCACPVTYTGKNCE 442 Y C C Y G NC+ Sbjct: 501 HGYVCECARGYGGPNCQ 517 Score = 40.7 bits (91), Expect = 0.003 Identities = 19/44 (43%), Positives = 21/44 (47%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPG 358 C C N C E HGYVC CA G+GG NC + PG Sbjct: 485 CEHAPCHNGATCHER--GHGYVCECARGYGGPNCQFLLPELPPG 526 Score = 40.3 bits (90), Expect = 0.004 Identities = 23/71 (32%), Positives = 31/71 (43%), Gaps = 3/71 (4%) Frame = +2 Query: 242 CLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESC-RPGLCGPG-KCMNTAD-SYKCAC 412 C+ C + + C C G+GG C++ C C G C NT SY C+C Sbjct: 257 CIRYPGCLHGTCQQPWQCNCQEGWGGLFCNQDLNYCTHHKPCKNGATCTNTGQGSYTCSC 316 Query: 413 PVTYTGKNCEV 445 YTG CE+ Sbjct: 317 RPGYTGATCEL 327 >BC117190-1|AAI17191.1| 1529|Homo sapiens slit homolog 2 (Drosophila) protein. Length = 1529 Score = 68.9 bits (161), Expect = 1e-11 Identities = 43/156 (27%), Positives = 72/156 (46%), Gaps = 6/156 (3%) Frame = +2 Query: 2 DNSGPFIAESPDQWTVLELNQPLYIGGVPDFDQLPI--DLAGASG--FVGCISMLILGNE 169 D P I + + + L + PLY+GG+P + G +G F GCI L + +E Sbjct: 1257 DGGNPKIITNLSKQSTLNFDSPLYVGGMPGKSNVASLRQAPGQNGTSFHGCIRNLYINSE 1316 Query: 170 EKNIMALALEKENVQNCFTCAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCD-RIGES 346 ++ + ++ + C C +C +G CQ + ++ G+ C C G+ G CD R + Sbjct: 1317 LQDFQKVPMQTGILPGCEPCHKKVCA-HGTCQPS-SQAGFTCECQEGWMGPLCDQRTNDP 1374 Query: 347 CRPGLCGPGKCMN-TADSYKCACPVTYTGKNCEVKQ 451 C C G C+ A SY C C + G C+ ++ Sbjct: 1375 CLGNKCVHGTCLPINAFSYSCKCLEGHGGVLCDEEE 1410 Score = 62.5 bits (145), Expect = 9e-10 Identities = 28/76 (36%), Positives = 39/76 (51%), Gaps = 2/76 (2%) Frame = +2 Query: 227 CAPNLCLNNGVCQ-EALTEHGYVCLCAPGFGGNNCDRIGESCRPGLC-GPGKCMNTADSY 400 C N C + G C + E G+ C+CA GF G NC+ + C C C++ ++Y Sbjct: 961 CISNPCKHGGTCHLKEGEEDGFWCICADGFEGENCEVNVDDCEDNDCENNSTCVDGINNY 1020 Query: 401 KCACPVTYTGKNCEVK 448 C CP YTG+ CE K Sbjct: 1021 TCLCPPEYTGELCEEK 1036 Score = 56.4 bits (130), Expect = 6e-08 Identities = 31/93 (33%), Positives = 44/93 (47%), Gaps = 4/93 (4%) Frame = +2 Query: 179 IMALALEKENVQ-NCFTCAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRP 355 I A E EN + N C N C NN C + + + Y CLC P + G C+ + C Sbjct: 985 ICADGFEGENCEVNVDDCEDNDCENNSTCVDGI--NNYTCLCPPEYTGELCEEKLDFCAQ 1042 Query: 356 GL--CG-PGKCMNTADSYKCACPVTYTGKNCEV 445 L C KC+ T +KC C Y G++C++ Sbjct: 1043 DLNPCQHDSKCILTPKGFKCDCTPGYVGEHCDI 1075 Score = 55.2 bits (127), Expect = 1e-07 Identities = 27/75 (36%), Positives = 38/75 (50%), Gaps = 3/75 (4%) Frame = +2 Query: 227 CAPNL--CLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLCGPG-KCMNTADS 397 CA +L C ++ C LT G+ C C PG+ G +CD + C+ C G C + + Sbjct: 1040 CAQDLNPCQHDSKC--ILTPKGFKCDCTPGYVGEHCDIDFDDCQDNKCKNGAHCTDAVNG 1097 Query: 398 YKCACPVTYTGKNCE 442 Y C CP Y+G CE Sbjct: 1098 YTCICPEGYSGLFCE 1112 Score = 48.4 bits (110), Expect = 2e-05 Identities = 27/80 (33%), Positives = 34/80 (42%), Gaps = 4/80 (5%) Frame = +2 Query: 218 CFTCAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLC-GPGKC---MN 385 C C N C N+G C + Y C C GF G +CD +C C G C Sbjct: 919 CNPCLSNPCKNDGTCNSDPVDF-YRCTCPYGFKGQDCDVPIHACISNPCKHGGTCHLKEG 977 Query: 386 TADSYKCACPVTYTGKNCEV 445 D + C C + G+NCEV Sbjct: 978 EEDGFWCICADGFEGENCEV 997 Score = 40.7 bits (91), Expect = 0.003 Identities = 24/76 (31%), Positives = 33/76 (43%), Gaps = 4/76 (5%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDR---IGESCRPGLCGPGKC-MNTAD 394 C N C++ G C + Y C C G GG CD + C+ C GKC ++ Sbjct: 1375 CLGNKCVH-GTCLP-INAFSYSCKCLEGHGGVLCDEEEDLFNPCQAIKCKHGKCRLSGLG 1432 Query: 395 SYKCACPVTYTGKNCE 442 C C YTG +C+ Sbjct: 1433 QPYCECSSGYTGDSCD 1448 >AL592301-5|CAI13934.1| 2555|Homo sapiens Notch homolog 1, translocation-associated (Drosophila) protein. Length = 2555 Score = 68.9 bits (161), Expect = 1e-11 Identities = 34/83 (40%), Positives = 41/83 (49%), Gaps = 3/83 (3%) Frame = +2 Query: 203 ENVQNCFTCAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESC--RPGLCGPG- 373 ++ Q CA N C N G C E Y+C C P F G C + C +PGLC G Sbjct: 136 KSCQQADPCASNPCANGGQCLPF--EASYICHCPPSFHGPTCRQDVNECGQKPGLCRHGG 193 Query: 374 KCMNTADSYKCACPVTYTGKNCE 442 C N SY+C C T+TG NCE Sbjct: 194 TCHNEVGSYRCVCRATHTGPNCE 216 Score = 68.1 bits (159), Expect = 2e-11 Identities = 30/74 (40%), Positives = 37/74 (50%), Gaps = 1/74 (1%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLC-GPGKCMNTADSYK 403 C N C+N G C++ + GYVC C GF G NC C C G C++ YK Sbjct: 757 CESNPCVNGGTCKDMTS--GYVCTCREGFSGPNCQTNINECASNPCLNQGTCIDDVAGYK 814 Query: 404 CACPVTYTGKNCEV 445 C C + YTG CEV Sbjct: 815 CNCLLPYTGATCEV 828 Score = 65.7 bits (153), Expect = 1e-10 Identities = 29/74 (39%), Positives = 39/74 (52%), Gaps = 2/74 (2%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESC--RPGLCGPGKCMNTADSY 400 C + C N G C + + + + CLC PGF G+ C C +P L G G C + SY Sbjct: 987 CTESSCFNGGTCVDGI--NSFTCLCPPGFTGSYCQHDVNECDSQPCLHG-GTCQDGCGSY 1043 Query: 401 KCACPVTYTGKNCE 442 +C CP YTG NC+ Sbjct: 1044 RCTCPQGYTGPNCQ 1057 Score = 64.5 bits (150), Expect = 2e-10 Identities = 26/77 (33%), Positives = 38/77 (49%) Frame = +2 Query: 215 NCFTCAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLCGPGKCMNTAD 394 N C+ C + G CQ+ ++ Y+C C G G NC+ + C C G C++ D Sbjct: 603 NINECSSQPCRHGGTCQDR--DNAYLCFCLKGTTGPNCEINLDDCASSPCDSGTCLDKID 660 Query: 395 SYKCACPVTYTGKNCEV 445 Y+CAC YTG C + Sbjct: 661 GYECACEPGYTGSMCNI 677 Score = 63.3 bits (147), Expect = 5e-10 Identities = 26/73 (35%), Positives = 37/73 (50%), Gaps = 1/73 (1%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLCGPG-KCMNTADSYK 403 CAP+ C N G C+++ + C+C G+ G C+ C C G C NT Y+ Sbjct: 833 CAPSPCRNGGECRQSEDYESFSCVCPTGWQGQTCEVDINECVLSPCRHGASCQNTHGGYR 892 Query: 404 CACPVTYTGKNCE 442 C C Y+G+NCE Sbjct: 893 CHCQAGYSGRNCE 905 Score = 60.9 bits (141), Expect = 3e-09 Identities = 25/72 (34%), Positives = 38/72 (52%), Gaps = 1/72 (1%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLC-GPGKCMNTADSYK 403 C+P+ C N G C+ + + C C PGF G NC+ + C C G C++ ++Y Sbjct: 222 CSPSPCQNGGTCRPT-GDVTHECACLPGFTGQNCEENIDDCPGNNCKNGGACVDGVNTYN 280 Query: 404 CACPVTYTGKNC 439 C CP +TG+ C Sbjct: 281 CRCPPEWTGQYC 292 Score = 60.5 bits (140), Expect = 4e-09 Identities = 29/78 (37%), Positives = 41/78 (52%), Gaps = 1/78 (1%) Frame = +2 Query: 215 NCFTCAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLCGPG-KCMNTA 391 N CA + CL+NG C + + E + C C GF G+ C + C C G KC++ Sbjct: 490 NTDECASSPCLHNGRCLDKINE--FQCECPTGFTGHLCQYDVDECASTPCKNGAKCLDGP 547 Query: 392 DSYKCACPVTYTGKNCEV 445 ++Y C C YTG +CEV Sbjct: 548 NTYTCVCTEGYTGTHCEV 565 Score = 60.1 bits (139), Expect = 5e-09 Identities = 30/82 (36%), Positives = 38/82 (46%), Gaps = 5/82 (6%) Frame = +2 Query: 212 QNCFT----CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLCGPG-K 376 +NC T C PN C N G C + + C C PGF G C+ C C G Sbjct: 902 RNCETDIDDCRPNPCHNGGSCTDGINTA--FCDCLPGFRGTFCEEDINECASDPCRNGAN 959 Query: 377 CMNTADSYKCACPVTYTGKNCE 442 C + DSY C CP ++G +CE Sbjct: 960 CTDCVDSYTCTCPAGFSGIHCE 981 Score = 59.3 bits (137), Expect = 8e-09 Identities = 29/80 (36%), Positives = 39/80 (48%), Gaps = 3/80 (3%) Frame = +2 Query: 215 NCFTCAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLC-GPGKCMNTA 391 N CA N CLN G C + + GY C C + G C+ + C P C G+C + Sbjct: 791 NINECASNPCLNQGTCIDDVA--GYKCNCLLPYTGATCEVVLAPCAPSPCRNGGECRQSE 848 Query: 392 D--SYKCACPVTYTGKNCEV 445 D S+ C CP + G+ CEV Sbjct: 849 DYESFSCVCPTGWQGQTCEV 868 Score = 59.3 bits (137), Expect = 8e-09 Identities = 27/74 (36%), Positives = 34/74 (45%), Gaps = 1/74 (1%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLC-GPGKCMNTADSYK 403 C CL+ G CQ+ Y C C G+ G NC + C C GKC T Y+ Sbjct: 1025 CDSQPCLHGGTCQDGCGS--YRCTCPQGYTGPNCQNLVHWCDSSPCKNGGKCWQTHTQYR 1082 Query: 404 CACPVTYTGKNCEV 445 C CP +TG C+V Sbjct: 1083 CECPSGWTGLYCDV 1096 Score = 59.3 bits (137), Expect = 8e-09 Identities = 26/74 (35%), Positives = 38/74 (51%), Gaps = 1/74 (1%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLC-GPGKCMNTADSYK 403 C+P+ C N C + L GY C C G+ G NC + C C G C++ ++YK Sbjct: 1149 CSPSPCQNGATCTDYLG--GYSCKCVAGYHGVNCSEEIDECLSHPCQNGGTCLDLPNTYK 1206 Query: 404 CACPVTYTGKNCEV 445 C+CP G +CE+ Sbjct: 1207 CSCPRGTQGVHCEI 1220 Score = 58.8 bits (136), Expect = 1e-08 Identities = 24/77 (31%), Positives = 37/77 (48%) Frame = +2 Query: 215 NCFTCAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLCGPGKCMNTAD 394 N CA N C N G C++ + +G+ C C G+ C C C G C ++ + Sbjct: 678 NIDECAGNPCHNGGTCEDGI--NGFTCRCPEGYHDPTCLSEVNECNSNPCVHGACRDSLN 735 Query: 395 SYKCACPVTYTGKNCEV 445 YKC C ++G NC++ Sbjct: 736 GYKCDCDPGWSGTNCDI 752 Score = 58.4 bits (135), Expect = 1e-08 Identities = 26/73 (35%), Positives = 37/73 (50%), Gaps = 1/73 (1%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLC-GPGKCMNTADSYK 403 C N C++ G C+++L +GY C C PG+ G NCD C C G C + Y Sbjct: 720 CNSNPCVH-GACRDSL--NGYKCDCDPGWSGTNCDINNNECESNPCVNGGTCKDMTSGYV 776 Query: 404 CACPVTYTGKNCE 442 C C ++G NC+ Sbjct: 777 CTCREGFSGPNCQ 789 Score = 57.2 bits (132), Expect = 3e-08 Identities = 22/73 (30%), Positives = 39/73 (53%), Gaps = 1/73 (1%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLC-GPGKCMNTADSYK 403 C N C N+ C + + E + C+C PG+ G +C+ + C C G+C++ + ++ Sbjct: 456 CVSNPCQNDATCLDQIGE--FQCICMPGYEGVHCEVNTDECASSPCLHNGRCLDKINEFQ 513 Query: 404 CACPVTYTGKNCE 442 C CP +TG C+ Sbjct: 514 CECPTGFTGHLCQ 526 Score = 55.2 bits (127), Expect = 1e-07 Identities = 26/72 (36%), Positives = 35/72 (48%), Gaps = 1/72 (1%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLC-GPGKCMNTADSYK 403 C N C N G C + LT Y C C PG+ G +C + + C C G+C+ SY Sbjct: 106 CLTNPCRNGGTC-DLLTLTEYKCRCPPGWSGKSCQQ-ADPCASNPCANGGQCLPFEASYI 163 Query: 404 CACPVTYTGKNC 439 C CP ++ G C Sbjct: 164 CHCPPSFHGPTC 175 Score = 55.2 bits (127), Expect = 1e-07 Identities = 29/83 (34%), Positives = 41/83 (49%), Gaps = 2/83 (2%) Frame = +2 Query: 200 KENVQNCFTCAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLC-GPGK 376 +++V C P LC + G C + Y C+C G NC+R C P C G Sbjct: 176 RQDVNECGQ-KPGLCRHGGTCHNEVGS--YRCVCRATHTGPNCERPYVPCSPSPCQNGGT 232 Query: 377 CMNTAD-SYKCACPVTYTGKNCE 442 C T D +++CAC +TG+NCE Sbjct: 233 CRPTGDVTHECACLPGFTGQNCE 255 Score = 55.2 bits (127), Expect = 1e-07 Identities = 23/72 (31%), Positives = 34/72 (47%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLCGPGKCMNTADSYKC 406 CA C N C + + Y C+C G+ G +C+ + C P C G C + ++ C Sbjct: 532 CASTPCKNGAKCLDG--PNTYTCVCTEGYTGTHCEVDIDECDPDPCHYGSCKDGVATFTC 589 Query: 407 ACPVTYTGKNCE 442 C YTG +CE Sbjct: 590 LCRPGYTGHHCE 601 Score = 55.2 bits (127), Expect = 1e-07 Identities = 24/70 (34%), Positives = 32/70 (45%), Gaps = 3/70 (4%) Frame = +2 Query: 242 CLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLC---GPGKCMNTADSYKCAC 412 C NNG C + + GY C C PGF G C+ C C G C+ + + C C Sbjct: 1238 CFNNGTCVDQVG--GYSCTCPPGFVGERCEGDVNECLSNPCDARGTQNCVQRVNDFHCEC 1295 Query: 413 PVTYTGKNCE 442 +TG+ CE Sbjct: 1296 RAGHTGRRCE 1305 Score = 54.4 bits (125), Expect = 2e-07 Identities = 26/83 (31%), Positives = 39/83 (46%), Gaps = 3/83 (3%) Frame = +2 Query: 239 LCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLCGPG-KCMNTADSYKCACP 415 LC + G+C +A H C C G+ G+ C+ + + C P C G C + Y C C Sbjct: 1115 LCQHGGLCVDAGNTHH--CRCQAGYTGSYCEDLVDECSPSPCQNGATCTDYLGGYSCKCV 1172 Query: 416 VTYTGKNC--EVKQLIEYPAFTG 478 Y G NC E+ + + +P G Sbjct: 1173 AGYHGVNCSEEIDECLSHPCQNG 1195 Score = 54.0 bits (124), Expect = 3e-07 Identities = 23/73 (31%), Positives = 34/73 (46%), Gaps = 1/73 (1%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLC-GPGKCMNTADSYK 403 CA + C N C + + Y C C GF G +C+ C C G C++ +S+ Sbjct: 949 CASDPCRNGANCTDCVDS--YTCTCPAGFSGIHCENNTPDCTESSCFNGGTCVDGINSFT 1006 Query: 404 CACPVTYTGKNCE 442 C CP +TG C+ Sbjct: 1007 CLCPPGFTGSYCQ 1019 Score = 52.0 bits (119), Expect = 1e-06 Identities = 26/79 (32%), Positives = 35/79 (44%), Gaps = 3/79 (3%) Frame = +2 Query: 212 QNCFTCAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCR--PGLC-GPGKCM 382 +N C N C N G C + + Y C C P + G C + C+ P C G C Sbjct: 256 ENIDDCPGNNCKNGGACVDGVNT--YNCRCPPEWTGQYCTEDVDECQLMPNACQNGGTCH 313 Query: 383 NTADSYKCACPVTYTGKNC 439 NT Y C C +TG++C Sbjct: 314 NTHGGYNCVCVNGWTGEDC 332 Score = 51.2 bits (117), Expect = 2e-06 Identities = 25/76 (32%), Positives = 33/76 (43%), Gaps = 3/76 (3%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGL--CG-PGKCMNTADS 397 C N C C +C C G+ G C + + C G C GKC+NT S Sbjct: 376 CISNPCNEGSNCDTNPVNGKAICTCPSGYTGPACSQDVDECSLGANPCEHAGKCINTLGS 435 Query: 398 YKCACPVTYTGKNCEV 445 ++C C YTG CE+ Sbjct: 436 FECQCLQGYTGPRCEI 451 Score = 50.8 bits (116), Expect = 3e-06 Identities = 24/74 (32%), Positives = 38/74 (51%), Gaps = 1/74 (1%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLC-GPGKCMNTADSYK 403 C P+ C + G C++ + + CLC PG+ G++C+ C C G C + ++Y Sbjct: 570 CDPDPC-HYGSCKDGVAT--FTCLCRPGYTGHHCETNINECSSQPCRHGGTCQDRDNAYL 626 Query: 404 CACPVTYTGKNCEV 445 C C TG NCE+ Sbjct: 627 CFCLKGTTGPNCEI 640 Score = 49.6 bits (113), Expect = 7e-06 Identities = 24/73 (32%), Positives = 33/73 (45%), Gaps = 1/73 (1%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLC-GPGKCMNTADSYK 403 C + C + CQ T GY C C G+ G NC+ + CRP C G C + ++ Sbjct: 873 CVLSPCRHGASCQN--THGGYRCHCQAGYSGRNCETDIDDCRPNPCHNGGSCTDGINTAF 930 Query: 404 CACPVTYTGKNCE 442 C C + G CE Sbjct: 931 CDCLPGFRGTFCE 943 Score = 49.6 bits (113), Expect = 7e-06 Identities = 24/74 (32%), Positives = 32/74 (43%), Gaps = 2/74 (2%) Frame = +2 Query: 227 CAPNLCLNNGVCQEAL-TEHGYVCLCAPGFGGNNCDRIGESCRPGLC-GPGKCMNTADSY 400 C C N G C A T G++C C GF G C+ +C C G C++ S Sbjct: 1311 CKGKPCKNGGTCAVASNTARGFICKCPAGFEGATCENDARTCGSLRCLNGGTCISGPRSP 1370 Query: 401 KCACPVTYTGKNCE 442 C C +TG C+ Sbjct: 1371 TCLCLGPFTGPECQ 1384 Score = 47.6 bits (108), Expect = 3e-05 Identities = 27/92 (29%), Positives = 41/92 (44%), Gaps = 3/92 (3%) Frame = +2 Query: 215 NCFTCAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLC-GPGKCMNTA 391 N CA + C ++G C + + GY C C PG+ G+ C+ + C C G C + Sbjct: 641 NLDDCASSPC-DSGTCLDKID--GYECACEPGYTGSMCNINIDECAGNPCHNGGTCEDGI 697 Query: 392 DSYKCACPVTYTGKNC--EVKQLIEYPAFTGS 481 + + C CP Y C EV + P G+ Sbjct: 698 NGFTCRCPEGYHDPTCLSEVNECNSNPCVHGA 729 Score = 46.8 bits (106), Expect = 5e-05 Identities = 27/78 (34%), Positives = 35/78 (44%), Gaps = 6/78 (7%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHG---YVCLCAPGFGGNNC-DRIGESCRPGLC-GPGKC-MNT 388 C C N G C + G Y C CA GF G C + +C C G C + T Sbjct: 63 CLSTPCKNAGTCH-VVDRRGVADYACSCALGFSGPLCLTPLDNACLTNPCRNGGTCDLLT 121 Query: 389 ADSYKCACPVTYTGKNCE 442 YKC CP ++GK+C+ Sbjct: 122 LTEYKCRCPPGWSGKSCQ 139 Score = 45.6 bits (103), Expect = 1e-04 Identities = 34/99 (34%), Positives = 42/99 (42%), Gaps = 5/99 (5%) Frame = +2 Query: 224 TCAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGES-CRPGL-C-GPGKCMNTAD 394 TC CLN G C CLC F G C S C G C G C T++ Sbjct: 1351 TCGSLRCLNGGTCISG--PRSPTCLCLGPFTGPECQFPASSPCLGGNPCYNQGTCEPTSE 1408 Query: 395 S--YKCACPVTYTGKNCEVKQLIEYPAFTGSA*LAIKPP 505 S Y+C CP + G C + ++Y +F G A I PP Sbjct: 1409 SPFYRCLCPAKFNGLLCHI---LDY-SFGGGAGRDIPPP 1443 Score = 43.2 bits (97), Expect = 6e-04 Identities = 31/91 (34%), Positives = 40/91 (43%), Gaps = 12/91 (13%) Frame = +2 Query: 206 NVQNCFT-CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESC-----RPG--- 358 N QN C + C N G C + T+ Y C C G+ G CD SC R G Sbjct: 1055 NCQNLVHWCDSSPCKNGGKCWQTHTQ--YRCECPSGWTGLYCDVPSVSCEVAAQRQGVDV 1112 Query: 359 --LCGPGK-CMNTADSYKCACPVTYTGKNCE 442 LC G C++ +++ C C YTG CE Sbjct: 1113 ARLCQHGGLCVDAGNTHHCRCQAGYTGSYCE 1143 Score = 43.2 bits (97), Expect = 6e-04 Identities = 23/81 (28%), Positives = 34/81 (41%), Gaps = 9/81 (11%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGL--------C-GPGKC 379 C + C N G C + + Y C C G G +C+ + C P + C G C Sbjct: 1187 CLSHPCQNGGTCLDL--PNTYKCSCPRGTQGVHCEINVDDCNPPVDPVSRSPKCFNNGTC 1244 Query: 380 MNTADSYKCACPVTYTGKNCE 442 ++ Y C CP + G+ CE Sbjct: 1245 VDQVGGYSCTCPPGFVGERCE 1265 Score = 41.1 bits (92), Expect = 0.002 Identities = 22/76 (28%), Positives = 29/76 (38%), Gaps = 4/76 (5%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLC-GPGKC---MNTAD 394 C N C G + + C C G G C+ + C+ C G C NTA Sbjct: 1271 CLSNPCDARGTQNCVQRVNDFHCECRAGHTGRRCESVINGCKGKPCKNGGTCAVASNTAR 1330 Query: 395 SYKCACPVTYTGKNCE 442 + C CP + G CE Sbjct: 1331 GFICKCPAGFEGATCE 1346 Score = 40.3 bits (90), Expect = 0.004 Identities = 22/82 (26%), Positives = 34/82 (41%), Gaps = 1/82 (1%) Frame = +2 Query: 203 ENVQNCFTCAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLC-GPGKC 379 ++V C + N C + G C L + C C G+ G C+ C C C Sbjct: 411 QDVDEC-SLGANPCEHAGKCINTLGS--FECQCLQGYTGPRCEIDVNECVSNPCQNDATC 467 Query: 380 MNTADSYKCACPVTYTGKNCEV 445 ++ ++C C Y G +CEV Sbjct: 468 LDQIGEFQCICMPGYEGVHCEV 489 Score = 32.3 bits (70), Expect = 1.1 Identities = 21/71 (29%), Positives = 29/71 (40%), Gaps = 5/71 (7%) Frame = +2 Query: 242 CLNNGVCQEALTEHGYVCLCAPGFGGNNCDR----IGESCR-PGLCGPGKCMNTADSYKC 406 CLN G C+ A C+C F G C + C+ G C AD Y C Sbjct: 31 CLNGGKCEAA--NGTEACVCGGAFVGPRCQDPNPCLSTPCKNAGTCHVVDRRGVAD-YAC 87 Query: 407 ACPVTYTGKNC 439 +C + ++G C Sbjct: 88 SCALGFSGPLC 98 >AL354671-1|CAI16149.1| 2555|Homo sapiens Notch homolog 1, translocation-associated (Drosophila) protein. Length = 2555 Score = 68.9 bits (161), Expect = 1e-11 Identities = 34/83 (40%), Positives = 41/83 (49%), Gaps = 3/83 (3%) Frame = +2 Query: 203 ENVQNCFTCAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESC--RPGLCGPG- 373 ++ Q CA N C N G C E Y+C C P F G C + C +PGLC G Sbjct: 136 KSCQQADPCASNPCANGGQCLPF--EASYICHCPPSFHGPTCRQDVNECGQKPGLCRHGG 193 Query: 374 KCMNTADSYKCACPVTYTGKNCE 442 C N SY+C C T+TG NCE Sbjct: 194 TCHNEVGSYRCVCRATHTGPNCE 216 Score = 68.1 bits (159), Expect = 2e-11 Identities = 30/74 (40%), Positives = 37/74 (50%), Gaps = 1/74 (1%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLC-GPGKCMNTADSYK 403 C N C+N G C++ + GYVC C GF G NC C C G C++ YK Sbjct: 757 CESNPCVNGGTCKDMTS--GYVCTCREGFSGPNCQTNINECASNPCLNQGTCIDDVAGYK 814 Query: 404 CACPVTYTGKNCEV 445 C C + YTG CEV Sbjct: 815 CNCLLPYTGATCEV 828 Score = 65.7 bits (153), Expect = 1e-10 Identities = 29/74 (39%), Positives = 39/74 (52%), Gaps = 2/74 (2%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESC--RPGLCGPGKCMNTADSY 400 C + C N G C + + + + CLC PGF G+ C C +P L G G C + SY Sbjct: 987 CTESSCFNGGTCVDGI--NSFTCLCPPGFTGSYCQHDVNECDSQPCLHG-GTCQDGCGSY 1043 Query: 401 KCACPVTYTGKNCE 442 +C CP YTG NC+ Sbjct: 1044 RCTCPQGYTGPNCQ 1057 Score = 64.5 bits (150), Expect = 2e-10 Identities = 26/77 (33%), Positives = 38/77 (49%) Frame = +2 Query: 215 NCFTCAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLCGPGKCMNTAD 394 N C+ C + G CQ+ ++ Y+C C G G NC+ + C C G C++ D Sbjct: 603 NINECSSQPCRHGGTCQDR--DNAYLCFCLKGTTGPNCEINLDDCASSPCDSGTCLDKID 660 Query: 395 SYKCACPVTYTGKNCEV 445 Y+CAC YTG C + Sbjct: 661 GYECACEPGYTGSMCNI 677 Score = 63.3 bits (147), Expect = 5e-10 Identities = 26/73 (35%), Positives = 37/73 (50%), Gaps = 1/73 (1%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLCGPG-KCMNTADSYK 403 CAP+ C N G C+++ + C+C G+ G C+ C C G C NT Y+ Sbjct: 833 CAPSPCRNGGECRQSEDYESFSCVCPTGWQGQTCEVDINECVLSPCRHGASCQNTHGGYR 892 Query: 404 CACPVTYTGKNCE 442 C C Y+G+NCE Sbjct: 893 CHCQAGYSGRNCE 905 Score = 60.9 bits (141), Expect = 3e-09 Identities = 25/72 (34%), Positives = 38/72 (52%), Gaps = 1/72 (1%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLC-GPGKCMNTADSYK 403 C+P+ C N G C+ + + C C PGF G NC+ + C C G C++ ++Y Sbjct: 222 CSPSPCQNGGTCRPT-GDVTHECACLPGFTGQNCEENIDDCPGNNCKNGGACVDGVNTYN 280 Query: 404 CACPVTYTGKNC 439 C CP +TG+ C Sbjct: 281 CRCPPEWTGQYC 292 Score = 60.5 bits (140), Expect = 4e-09 Identities = 29/78 (37%), Positives = 41/78 (52%), Gaps = 1/78 (1%) Frame = +2 Query: 215 NCFTCAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLCGPG-KCMNTA 391 N CA + CL+NG C + + E + C C GF G+ C + C C G KC++ Sbjct: 490 NTDECASSPCLHNGRCLDKINE--FQCECPTGFTGHLCQYDVDECASTPCKNGAKCLDGP 547 Query: 392 DSYKCACPVTYTGKNCEV 445 ++Y C C YTG +CEV Sbjct: 548 NTYTCVCTEGYTGTHCEV 565 Score = 60.1 bits (139), Expect = 5e-09 Identities = 30/82 (36%), Positives = 38/82 (46%), Gaps = 5/82 (6%) Frame = +2 Query: 212 QNCFT----CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLCGPG-K 376 +NC T C PN C N G C + + C C PGF G C+ C C G Sbjct: 902 RNCETDIDDCRPNPCHNGGSCTDGINTA--FCDCLPGFRGTFCEEDINECASDPCRNGAN 959 Query: 377 CMNTADSYKCACPVTYTGKNCE 442 C + DSY C CP ++G +CE Sbjct: 960 CTDCVDSYTCTCPAGFSGIHCE 981 Score = 59.3 bits (137), Expect = 8e-09 Identities = 29/80 (36%), Positives = 39/80 (48%), Gaps = 3/80 (3%) Frame = +2 Query: 215 NCFTCAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLC-GPGKCMNTA 391 N CA N CLN G C + + GY C C + G C+ + C P C G+C + Sbjct: 791 NINECASNPCLNQGTCIDDVA--GYKCNCLLPYTGATCEVVLAPCAPSPCRNGGECRQSE 848 Query: 392 D--SYKCACPVTYTGKNCEV 445 D S+ C CP + G+ CEV Sbjct: 849 DYESFSCVCPTGWQGQTCEV 868 Score = 59.3 bits (137), Expect = 8e-09 Identities = 27/74 (36%), Positives = 34/74 (45%), Gaps = 1/74 (1%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLC-GPGKCMNTADSYK 403 C CL+ G CQ+ Y C C G+ G NC + C C GKC T Y+ Sbjct: 1025 CDSQPCLHGGTCQDGCGS--YRCTCPQGYTGPNCQNLVHWCDSSPCKNGGKCWQTHTQYR 1082 Query: 404 CACPVTYTGKNCEV 445 C CP +TG C+V Sbjct: 1083 CECPSGWTGLYCDV 1096 Score = 59.3 bits (137), Expect = 8e-09 Identities = 26/74 (35%), Positives = 38/74 (51%), Gaps = 1/74 (1%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLC-GPGKCMNTADSYK 403 C+P+ C N C + L GY C C G+ G NC + C C G C++ ++YK Sbjct: 1149 CSPSPCQNGATCTDYLG--GYSCKCVAGYHGVNCSEEIDECLSHPCQNGGTCLDLPNTYK 1206 Query: 404 CACPVTYTGKNCEV 445 C+CP G +CE+ Sbjct: 1207 CSCPRGTQGVHCEI 1220 Score = 58.8 bits (136), Expect = 1e-08 Identities = 24/77 (31%), Positives = 37/77 (48%) Frame = +2 Query: 215 NCFTCAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLCGPGKCMNTAD 394 N CA N C N G C++ + +G+ C C G+ C C C G C ++ + Sbjct: 678 NIDECAGNPCHNGGTCEDGI--NGFTCRCPEGYHDPTCLSEVNECNSNPCVHGACRDSLN 735 Query: 395 SYKCACPVTYTGKNCEV 445 YKC C ++G NC++ Sbjct: 736 GYKCDCDPGWSGTNCDI 752 Score = 58.4 bits (135), Expect = 1e-08 Identities = 26/73 (35%), Positives = 37/73 (50%), Gaps = 1/73 (1%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLC-GPGKCMNTADSYK 403 C N C++ G C+++L +GY C C PG+ G NCD C C G C + Y Sbjct: 720 CNSNPCVH-GACRDSL--NGYKCDCDPGWSGTNCDINNNECESNPCVNGGTCKDMTSGYV 776 Query: 404 CACPVTYTGKNCE 442 C C ++G NC+ Sbjct: 777 CTCREGFSGPNCQ 789 Score = 57.2 bits (132), Expect = 3e-08 Identities = 22/73 (30%), Positives = 39/73 (53%), Gaps = 1/73 (1%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLC-GPGKCMNTADSYK 403 C N C N+ C + + E + C+C PG+ G +C+ + C C G+C++ + ++ Sbjct: 456 CVSNPCQNDATCLDQIGE--FQCICMPGYEGVHCEVNTDECASSPCLHNGRCLDKINEFQ 513 Query: 404 CACPVTYTGKNCE 442 C CP +TG C+ Sbjct: 514 CECPTGFTGHLCQ 526 Score = 55.2 bits (127), Expect = 1e-07 Identities = 26/72 (36%), Positives = 35/72 (48%), Gaps = 1/72 (1%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLC-GPGKCMNTADSYK 403 C N C N G C + LT Y C C PG+ G +C + + C C G+C+ SY Sbjct: 106 CLTNPCRNGGTC-DLLTLTEYKCRCPPGWSGKSCQQ-ADPCASNPCANGGQCLPFEASYI 163 Query: 404 CACPVTYTGKNC 439 C CP ++ G C Sbjct: 164 CHCPPSFHGPTC 175 Score = 55.2 bits (127), Expect = 1e-07 Identities = 29/83 (34%), Positives = 41/83 (49%), Gaps = 2/83 (2%) Frame = +2 Query: 200 KENVQNCFTCAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLC-GPGK 376 +++V C P LC + G C + Y C+C G NC+R C P C G Sbjct: 176 RQDVNECGQ-KPGLCRHGGTCHNEVGS--YRCVCRATHTGPNCERPYVPCSPSPCQNGGT 232 Query: 377 CMNTAD-SYKCACPVTYTGKNCE 442 C T D +++CAC +TG+NCE Sbjct: 233 CRPTGDVTHECACLPGFTGQNCE 255 Score = 55.2 bits (127), Expect = 1e-07 Identities = 23/72 (31%), Positives = 34/72 (47%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLCGPGKCMNTADSYKC 406 CA C N C + + Y C+C G+ G +C+ + C P C G C + ++ C Sbjct: 532 CASTPCKNGAKCLDG--PNTYTCVCTEGYTGTHCEVDIDECDPDPCHYGSCKDGVATFTC 589 Query: 407 ACPVTYTGKNCE 442 C YTG +CE Sbjct: 590 LCRPGYTGHHCE 601 Score = 55.2 bits (127), Expect = 1e-07 Identities = 24/70 (34%), Positives = 32/70 (45%), Gaps = 3/70 (4%) Frame = +2 Query: 242 CLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLC---GPGKCMNTADSYKCAC 412 C NNG C + + GY C C PGF G C+ C C G C+ + + C C Sbjct: 1238 CFNNGTCVDQVG--GYSCTCPPGFVGERCEGDVNECLSNPCDARGTQNCVQRVNDFHCEC 1295 Query: 413 PVTYTGKNCE 442 +TG+ CE Sbjct: 1296 RAGHTGRRCE 1305 Score = 54.4 bits (125), Expect = 2e-07 Identities = 26/83 (31%), Positives = 39/83 (46%), Gaps = 3/83 (3%) Frame = +2 Query: 239 LCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLCGPG-KCMNTADSYKCACP 415 LC + G+C +A H C C G+ G+ C+ + + C P C G C + Y C C Sbjct: 1115 LCQHGGLCVDAGNTHH--CRCQAGYTGSYCEDLVDECSPSPCQNGATCTDYLGGYSCKCV 1172 Query: 416 VTYTGKNC--EVKQLIEYPAFTG 478 Y G NC E+ + + +P G Sbjct: 1173 AGYHGVNCSEEIDECLSHPCQNG 1195 Score = 54.0 bits (124), Expect = 3e-07 Identities = 23/73 (31%), Positives = 34/73 (46%), Gaps = 1/73 (1%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLC-GPGKCMNTADSYK 403 CA + C N C + + Y C C GF G +C+ C C G C++ +S+ Sbjct: 949 CASDPCRNGANCTDCVDS--YTCTCPAGFSGIHCENNTPDCTESSCFNGGTCVDGINSFT 1006 Query: 404 CACPVTYTGKNCE 442 C CP +TG C+ Sbjct: 1007 CLCPPGFTGSYCQ 1019 Score = 52.0 bits (119), Expect = 1e-06 Identities = 26/79 (32%), Positives = 35/79 (44%), Gaps = 3/79 (3%) Frame = +2 Query: 212 QNCFTCAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCR--PGLC-GPGKCM 382 +N C N C N G C + + Y C C P + G C + C+ P C G C Sbjct: 256 ENIDDCPGNNCKNGGACVDGVNT--YNCRCPPEWTGQYCTEDVDECQLMPNACQNGGTCH 313 Query: 383 NTADSYKCACPVTYTGKNC 439 NT Y C C +TG++C Sbjct: 314 NTHGGYNCVCVNGWTGEDC 332 Score = 51.2 bits (117), Expect = 2e-06 Identities = 25/76 (32%), Positives = 33/76 (43%), Gaps = 3/76 (3%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGL--CG-PGKCMNTADS 397 C N C C +C C G+ G C + + C G C GKC+NT S Sbjct: 376 CISNPCNEGSNCDTNPVNGKAICTCPSGYTGPACSQDVDECSLGANPCEHAGKCINTLGS 435 Query: 398 YKCACPVTYTGKNCEV 445 ++C C YTG CE+ Sbjct: 436 FECQCLQGYTGPRCEI 451 Score = 50.8 bits (116), Expect = 3e-06 Identities = 24/74 (32%), Positives = 38/74 (51%), Gaps = 1/74 (1%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLC-GPGKCMNTADSYK 403 C P+ C + G C++ + + CLC PG+ G++C+ C C G C + ++Y Sbjct: 570 CDPDPC-HYGSCKDGVAT--FTCLCRPGYTGHHCETNINECSSQPCRHGGTCQDRDNAYL 626 Query: 404 CACPVTYTGKNCEV 445 C C TG NCE+ Sbjct: 627 CFCLKGTTGPNCEI 640 Score = 49.6 bits (113), Expect = 7e-06 Identities = 24/73 (32%), Positives = 33/73 (45%), Gaps = 1/73 (1%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLC-GPGKCMNTADSYK 403 C + C + CQ T GY C C G+ G NC+ + CRP C G C + ++ Sbjct: 873 CVLSPCRHGASCQN--THGGYRCHCQAGYSGRNCETDIDDCRPNPCHNGGSCTDGINTAF 930 Query: 404 CACPVTYTGKNCE 442 C C + G CE Sbjct: 931 CDCLPGFRGTFCE 943 Score = 49.6 bits (113), Expect = 7e-06 Identities = 24/74 (32%), Positives = 32/74 (43%), Gaps = 2/74 (2%) Frame = +2 Query: 227 CAPNLCLNNGVCQEAL-TEHGYVCLCAPGFGGNNCDRIGESCRPGLC-GPGKCMNTADSY 400 C C N G C A T G++C C GF G C+ +C C G C++ S Sbjct: 1311 CKGKPCKNGGTCAVASNTARGFICKCPAGFEGATCENDARTCGSLRCLNGGTCISGPRSP 1370 Query: 401 KCACPVTYTGKNCE 442 C C +TG C+ Sbjct: 1371 TCLCLGPFTGPECQ 1384 Score = 47.6 bits (108), Expect = 3e-05 Identities = 27/92 (29%), Positives = 41/92 (44%), Gaps = 3/92 (3%) Frame = +2 Query: 215 NCFTCAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLC-GPGKCMNTA 391 N CA + C ++G C + + GY C C PG+ G+ C+ + C C G C + Sbjct: 641 NLDDCASSPC-DSGTCLDKID--GYECACEPGYTGSMCNINIDECAGNPCHNGGTCEDGI 697 Query: 392 DSYKCACPVTYTGKNC--EVKQLIEYPAFTGS 481 + + C CP Y C EV + P G+ Sbjct: 698 NGFTCRCPEGYHDPTCLSEVNECNSNPCVHGA 729 Score = 46.8 bits (106), Expect = 5e-05 Identities = 27/78 (34%), Positives = 35/78 (44%), Gaps = 6/78 (7%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHG---YVCLCAPGFGGNNC-DRIGESCRPGLC-GPGKC-MNT 388 C C N G C + G Y C CA GF G C + +C C G C + T Sbjct: 63 CLSTPCKNAGTCH-VVDRRGVADYACSCALGFSGPLCLTPLDNACLTNPCRNGGTCDLLT 121 Query: 389 ADSYKCACPVTYTGKNCE 442 YKC CP ++GK+C+ Sbjct: 122 LTEYKCRCPPGWSGKSCQ 139 Score = 45.6 bits (103), Expect = 1e-04 Identities = 34/99 (34%), Positives = 42/99 (42%), Gaps = 5/99 (5%) Frame = +2 Query: 224 TCAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGES-CRPGL-C-GPGKCMNTAD 394 TC CLN G C CLC F G C S C G C G C T++ Sbjct: 1351 TCGSLRCLNGGTCISG--PRSPTCLCLGPFTGPECQFPASSPCLGGNPCYNQGTCEPTSE 1408 Query: 395 S--YKCACPVTYTGKNCEVKQLIEYPAFTGSA*LAIKPP 505 S Y+C CP + G C + ++Y +F G A I PP Sbjct: 1409 SPFYRCLCPAKFNGLLCHI---LDY-SFGGGAGRDIPPP 1443 Score = 43.2 bits (97), Expect = 6e-04 Identities = 31/91 (34%), Positives = 40/91 (43%), Gaps = 12/91 (13%) Frame = +2 Query: 206 NVQNCFT-CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESC-----RPG--- 358 N QN C + C N G C + T+ Y C C G+ G CD SC R G Sbjct: 1055 NCQNLVHWCDSSPCKNGGKCWQTHTQ--YRCECPSGWTGLYCDVPSVSCEVAAQRQGVDV 1112 Query: 359 --LCGPGK-CMNTADSYKCACPVTYTGKNCE 442 LC G C++ +++ C C YTG CE Sbjct: 1113 ARLCQHGGLCVDAGNTHHCRCQAGYTGSYCE 1143 Score = 43.2 bits (97), Expect = 6e-04 Identities = 23/81 (28%), Positives = 34/81 (41%), Gaps = 9/81 (11%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGL--------C-GPGKC 379 C + C N G C + + Y C C G G +C+ + C P + C G C Sbjct: 1187 CLSHPCQNGGTCLDL--PNTYKCSCPRGTQGVHCEINVDDCNPPVDPVSRSPKCFNNGTC 1244 Query: 380 MNTADSYKCACPVTYTGKNCE 442 ++ Y C CP + G+ CE Sbjct: 1245 VDQVGGYSCTCPPGFVGERCE 1265 Score = 41.1 bits (92), Expect = 0.002 Identities = 22/76 (28%), Positives = 29/76 (38%), Gaps = 4/76 (5%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLC-GPGKC---MNTAD 394 C N C G + + C C G G C+ + C+ C G C NTA Sbjct: 1271 CLSNPCDARGTQNCVQRVNDFHCECRAGHTGRRCESVINGCKGKPCKNGGTCAVASNTAR 1330 Query: 395 SYKCACPVTYTGKNCE 442 + C CP + G CE Sbjct: 1331 GFICKCPAGFEGATCE 1346 Score = 40.3 bits (90), Expect = 0.004 Identities = 22/82 (26%), Positives = 34/82 (41%), Gaps = 1/82 (1%) Frame = +2 Query: 203 ENVQNCFTCAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLC-GPGKC 379 ++V C + N C + G C L + C C G+ G C+ C C C Sbjct: 411 QDVDEC-SLGANPCEHAGKCINTLGS--FECQCLQGYTGPRCEIDVNECVSNPCQNDATC 467 Query: 380 MNTADSYKCACPVTYTGKNCEV 445 ++ ++C C Y G +CEV Sbjct: 468 LDQIGEFQCICMPGYEGVHCEV 489 Score = 32.3 bits (70), Expect = 1.1 Identities = 21/71 (29%), Positives = 29/71 (40%), Gaps = 5/71 (7%) Frame = +2 Query: 242 CLNNGVCQEALTEHGYVCLCAPGFGGNNCDR----IGESCR-PGLCGPGKCMNTADSYKC 406 CLN G C+ A C+C F G C + C+ G C AD Y C Sbjct: 31 CLNGGKCEAA--NGTEACVCGGAFVGPRCQDPNPCLSTPCKNAGTCHVVDRRGVAD-YAC 87 Query: 407 ACPVTYTGKNC 439 +C + ++G C Sbjct: 88 SCALGFSGPLC 98 >AF133270-1|AAD25539.1| 1525|Homo sapiens SLIT2 protein. Length = 1525 Score = 68.9 bits (161), Expect = 1e-11 Identities = 43/156 (27%), Positives = 72/156 (46%), Gaps = 6/156 (3%) Frame = +2 Query: 2 DNSGPFIAESPDQWTVLELNQPLYIGGVPDFDQLPI--DLAGASG--FVGCISMLILGNE 169 D P I + + + L + PLY+GG+P + G +G F GCI L + +E Sbjct: 1253 DGGNPKIITNLSKQSTLNFDSPLYVGGMPGKSNVASLRQAPGQNGTSFHGCIRNLYINSE 1312 Query: 170 EKNIMALALEKENVQNCFTCAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCD-RIGES 346 ++ + ++ + C C +C +G CQ + ++ G+ C C G+ G CD R + Sbjct: 1313 LQDFQKVPMQTGILPGCEPCHKKVCA-HGTCQPS-SQAGFTCECQEGWMGPLCDQRTNDP 1370 Query: 347 CRPGLCGPGKCMN-TADSYKCACPVTYTGKNCEVKQ 451 C C G C+ A SY C C + G C+ ++ Sbjct: 1371 CLGNKCVHGTCLPINAFSYSCKCLEGHGGVLCDEEE 1406 Score = 62.5 bits (145), Expect = 9e-10 Identities = 28/76 (36%), Positives = 39/76 (51%), Gaps = 2/76 (2%) Frame = +2 Query: 227 CAPNLCLNNGVCQ-EALTEHGYVCLCAPGFGGNNCDRIGESCRPGLC-GPGKCMNTADSY 400 C N C + G C + E G+ C+CA GF G NC+ + C C C++ ++Y Sbjct: 957 CISNPCKHGGTCHLKEGEEDGFWCICADGFEGENCEVNVDDCEDNDCENNSTCVDGINNY 1016 Query: 401 KCACPVTYTGKNCEVK 448 C CP YTG+ CE K Sbjct: 1017 TCLCPPEYTGELCEEK 1032 Score = 56.4 bits (130), Expect = 6e-08 Identities = 31/93 (33%), Positives = 44/93 (47%), Gaps = 4/93 (4%) Frame = +2 Query: 179 IMALALEKENVQ-NCFTCAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRP 355 I A E EN + N C N C NN C + + + Y CLC P + G C+ + C Sbjct: 981 ICADGFEGENCEVNVDDCEDNDCENNSTCVDGI--NNYTCLCPPEYTGELCEEKLDFCAQ 1038 Query: 356 GL--CG-PGKCMNTADSYKCACPVTYTGKNCEV 445 L C KC+ T +KC C Y G++C++ Sbjct: 1039 DLNPCQHDSKCILTPKGFKCDCTPGYVGEHCDI 1071 Score = 55.2 bits (127), Expect = 1e-07 Identities = 27/75 (36%), Positives = 38/75 (50%), Gaps = 3/75 (4%) Frame = +2 Query: 227 CAPNL--CLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLCGPG-KCMNTADS 397 CA +L C ++ C LT G+ C C PG+ G +CD + C+ C G C + + Sbjct: 1036 CAQDLNPCQHDSKC--ILTPKGFKCDCTPGYVGEHCDIDFDDCQDNKCKNGAHCTDAVNG 1093 Query: 398 YKCACPVTYTGKNCE 442 Y C CP Y+G CE Sbjct: 1094 YTCICPEGYSGLFCE 1108 Score = 48.4 bits (110), Expect = 2e-05 Identities = 27/80 (33%), Positives = 34/80 (42%), Gaps = 4/80 (5%) Frame = +2 Query: 218 CFTCAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLC-GPGKC---MN 385 C C N C N+G C + Y C C GF G +CD +C C G C Sbjct: 915 CNPCLSNPCKNDGTCNSDPVDF-YRCTCPYGFKGQDCDVPIHACISNPCKHGGTCHLKEG 973 Query: 386 TADSYKCACPVTYTGKNCEV 445 D + C C + G+NCEV Sbjct: 974 EEDGFWCICADGFEGENCEV 993 Score = 40.7 bits (91), Expect = 0.003 Identities = 24/76 (31%), Positives = 33/76 (43%), Gaps = 4/76 (5%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDR---IGESCRPGLCGPGKC-MNTAD 394 C N C++ G C + Y C C G GG CD + C+ C GKC ++ Sbjct: 1371 CLGNKCVH-GTCLP-INAFSYSCKCLEGHGGVLCDEEEDLFNPCQAIKCKHGKCRLSGLG 1428 Query: 395 SYKCACPVTYTGKNCE 442 C C YTG +C+ Sbjct: 1429 QPYCECSSGYTGDSCD 1444 >AF055585-1|AAD04309.1| 1521|Homo sapiens neurogenic extracellular slit protein Slit2 protein. Length = 1521 Score = 68.9 bits (161), Expect = 1e-11 Identities = 43/156 (27%), Positives = 72/156 (46%), Gaps = 6/156 (3%) Frame = +2 Query: 2 DNSGPFIAESPDQWTVLELNQPLYIGGVPDFDQLPI--DLAGASG--FVGCISMLILGNE 169 D P I + + + L + PLY+GG+P + G +G F GCI L + +E Sbjct: 1249 DGGNPKIITNLSKQSTLNFDSPLYVGGMPGKSNVASLRQAPGQNGTSFHGCIRNLYINSE 1308 Query: 170 EKNIMALALEKENVQNCFTCAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCD-RIGES 346 ++ + ++ + C C +C +G CQ + ++ G+ C C G+ G CD R + Sbjct: 1309 LQDFQKVPMQTGILPGCEPCHKKVCA-HGTCQPS-SQAGFTCECQEGWMGPLCDQRTNDP 1366 Query: 347 CRPGLCGPGKCMN-TADSYKCACPVTYTGKNCEVKQ 451 C C G C+ A SY C C + G C+ ++ Sbjct: 1367 CLGNKCVHGTCLPINAFSYSCKCLEGHGGVLCDEEE 1402 Score = 62.5 bits (145), Expect = 9e-10 Identities = 28/76 (36%), Positives = 39/76 (51%), Gaps = 2/76 (2%) Frame = +2 Query: 227 CAPNLCLNNGVCQ-EALTEHGYVCLCAPGFGGNNCDRIGESCRPGLC-GPGKCMNTADSY 400 C N C + G C + E G+ C+CA GF G NC+ + C C C++ ++Y Sbjct: 953 CISNPCKHGGTCHLKEGEEDGFWCICADGFEGENCEVNVDDCEDNDCENNSTCVDGINNY 1012 Query: 401 KCACPVTYTGKNCEVK 448 C CP YTG+ CE K Sbjct: 1013 TCLCPPEYTGELCEEK 1028 Score = 56.4 bits (130), Expect = 6e-08 Identities = 31/93 (33%), Positives = 44/93 (47%), Gaps = 4/93 (4%) Frame = +2 Query: 179 IMALALEKENVQ-NCFTCAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRP 355 I A E EN + N C N C NN C + + + Y CLC P + G C+ + C Sbjct: 977 ICADGFEGENCEVNVDDCEDNDCENNSTCVDGI--NNYTCLCPPEYTGELCEEKLDFCAQ 1034 Query: 356 GL--CG-PGKCMNTADSYKCACPVTYTGKNCEV 445 L C KC+ T +KC C Y G++C++ Sbjct: 1035 DLNPCQHDSKCILTPKGFKCDCTPGYVGEHCDI 1067 Score = 55.2 bits (127), Expect = 1e-07 Identities = 27/75 (36%), Positives = 38/75 (50%), Gaps = 3/75 (4%) Frame = +2 Query: 227 CAPNL--CLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLCGPG-KCMNTADS 397 CA +L C ++ C LT G+ C C PG+ G +CD + C+ C G C + + Sbjct: 1032 CAQDLNPCQHDSKC--ILTPKGFKCDCTPGYVGEHCDIDFDDCQDNKCKNGAHCTDAVNG 1089 Query: 398 YKCACPVTYTGKNCE 442 Y C CP Y+G CE Sbjct: 1090 YTCICPEGYSGLFCE 1104 Score = 48.4 bits (110), Expect = 2e-05 Identities = 27/80 (33%), Positives = 34/80 (42%), Gaps = 4/80 (5%) Frame = +2 Query: 218 CFTCAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLC-GPGKC---MN 385 C C N C N+G C + Y C C GF G +CD +C C G C Sbjct: 911 CNPCLSNPCKNDGTCNSDPVDF-YRCTCPYGFKGQDCDVPIHACISNPCKHGGTCHLKEG 969 Query: 386 TADSYKCACPVTYTGKNCEV 445 D + C C + G+NCEV Sbjct: 970 EEDGFWCICADGFEGENCEV 989 Score = 40.7 bits (91), Expect = 0.003 Identities = 24/76 (31%), Positives = 33/76 (43%), Gaps = 4/76 (5%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDR---IGESCRPGLCGPGKC-MNTAD 394 C N C++ G C + Y C C G GG CD + C+ C GKC ++ Sbjct: 1367 CLGNKCVH-GTCLP-INAFSYSCKCLEGHGGVLCDEEEDLFNPCQAIKCKHGKCRLSGLG 1424 Query: 395 SYKCACPVTYTGKNCE 442 C C YTG +C+ Sbjct: 1425 QPYCECSSGYTGDSCD 1440 >AB017168-1|BAA35185.1| 1529|Homo sapiens Slit-2 protein protein. Length = 1529 Score = 68.9 bits (161), Expect = 1e-11 Identities = 43/156 (27%), Positives = 72/156 (46%), Gaps = 6/156 (3%) Frame = +2 Query: 2 DNSGPFIAESPDQWTVLELNQPLYIGGVPDFDQLPI--DLAGASG--FVGCISMLILGNE 169 D P I + + + L + PLY+GG+P + G +G F GCI L + +E Sbjct: 1257 DGGNPKIITNLSKQSTLNFDSPLYVGGMPGKSNVASLRQAPGQNGTSFHGCIRNLYINSE 1316 Query: 170 EKNIMALALEKENVQNCFTCAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCD-RIGES 346 ++ + ++ + C C +C +G CQ + ++ G+ C C G+ G CD R + Sbjct: 1317 LQDFQKVPMQTGILPGCEPCHKKVCA-HGTCQPS-SQAGFTCECQEGWMGPLCDQRTNDP 1374 Query: 347 CRPGLCGPGKCMN-TADSYKCACPVTYTGKNCEVKQ 451 C C G C+ A SY C C + G C+ ++ Sbjct: 1375 CLGNKCVHGTCLPINAFSYSCKCLEGHGGVLCDEEE 1410 Score = 62.5 bits (145), Expect = 9e-10 Identities = 28/76 (36%), Positives = 39/76 (51%), Gaps = 2/76 (2%) Frame = +2 Query: 227 CAPNLCLNNGVCQ-EALTEHGYVCLCAPGFGGNNCDRIGESCRPGLC-GPGKCMNTADSY 400 C N C + G C + E G+ C+CA GF G NC+ + C C C++ ++Y Sbjct: 961 CISNPCKHGGTCHLKEGEEDGFWCICADGFEGENCEVNVDDCEDNDCENNSTCVDGINNY 1020 Query: 401 KCACPVTYTGKNCEVK 448 C CP YTG+ CE K Sbjct: 1021 TCLCPPEYTGELCEEK 1036 Score = 56.4 bits (130), Expect = 6e-08 Identities = 31/93 (33%), Positives = 44/93 (47%), Gaps = 4/93 (4%) Frame = +2 Query: 179 IMALALEKENVQ-NCFTCAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRP 355 I A E EN + N C N C NN C + + + Y CLC P + G C+ + C Sbjct: 985 ICADGFEGENCEVNVDDCEDNDCENNSTCVDGI--NNYTCLCPPEYTGELCEEKLDFCAQ 1042 Query: 356 GL--CG-PGKCMNTADSYKCACPVTYTGKNCEV 445 L C KC+ T +KC C Y G++C++ Sbjct: 1043 DLNPCQHDSKCILTPKGFKCDCTPGYVGEHCDI 1075 Score = 55.2 bits (127), Expect = 1e-07 Identities = 27/75 (36%), Positives = 38/75 (50%), Gaps = 3/75 (4%) Frame = +2 Query: 227 CAPNL--CLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLCGPG-KCMNTADS 397 CA +L C ++ C LT G+ C C PG+ G +CD + C+ C G C + + Sbjct: 1040 CAQDLNPCQHDSKC--ILTPKGFKCDCTPGYVGEHCDIDFDDCQDNKCKNGAHCTDAVNG 1097 Query: 398 YKCACPVTYTGKNCE 442 Y C CP Y+G CE Sbjct: 1098 YTCICPEGYSGLFCE 1112 Score = 48.4 bits (110), Expect = 2e-05 Identities = 27/80 (33%), Positives = 34/80 (42%), Gaps = 4/80 (5%) Frame = +2 Query: 218 CFTCAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLC-GPGKC---MN 385 C C N C N+G C + Y C C GF G +CD +C C G C Sbjct: 919 CNPCLSNPCKNDGTCNSDPVDF-YRCTCPYGFKGQDCDVPIHACISNPCKHGGTCHLKEG 977 Query: 386 TADSYKCACPVTYTGKNCEV 445 D + C C + G+NCEV Sbjct: 978 EEDGFWCICADGFEGENCEV 997 Score = 40.7 bits (91), Expect = 0.003 Identities = 24/76 (31%), Positives = 33/76 (43%), Gaps = 4/76 (5%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDR---IGESCRPGLCGPGKC-MNTAD 394 C N C++ G C + Y C C G GG CD + C+ C GKC ++ Sbjct: 1375 CLGNKCVH-GTCLP-INAFSYSCKCLEGHGGVLCDEEEDLFNPCQAIKCKHGKCRLSGLG 1432 Query: 395 SYKCACPVTYTGKNCE 442 C C YTG +C+ Sbjct: 1433 QPYCECSSGYTGDSCD 1448 >BC039143-1|AAH39143.1| 740|Homo sapiens FAT2 protein protein. Length = 740 Score = 68.5 bits (160), Expect = 1e-11 Identities = 38/120 (31%), Positives = 57/120 (47%), Gaps = 11/120 (9%) Frame = +2 Query: 122 ASGFVGCISMLILGNEEKNIMALA------LEKENVQNCFT----CAPNLCLNNGVCQEA 271 + GF GC+ +++ E +++A LE + + C C+ N CLN G C Sbjct: 297 SQGFEGCLDAVVVNEEALDLLAPGKTVAGLLETQALTQCCLHSDYCSQNTCLNGGKCSWT 356 Query: 272 LTEHGYVCLCAPGFGGNNCDRIGESCRPGLC-GPGKCMNTADSYKCACPVTYTGKNCEVK 448 GYVC C P F G +C++ E+C C G C+ + C CP YTG CE++ Sbjct: 357 HGA-GYVCKCPPQFSGKHCEQGRENCTFAPCLEGGTCILSPKGASCNCPHPYTGDRCEME 415 Score = 32.3 bits (70), Expect = 1.1 Identities = 18/51 (35%), Positives = 23/51 (45%) Frame = +2 Query: 212 QNCFTCAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLC 364 +NC T AP CL G C L+ G C C + G+ C+ C G C Sbjct: 379 ENC-TFAP--CLEGGTC--ILSPKGASCNCPHPYTGDRCEMEARGCSEGHC 424 >AF231022-1|AAF61928.1| 4349|Homo sapiens protocadherin Fat 2 protein. Length = 4349 Score = 68.5 bits (160), Expect = 1e-11 Identities = 38/120 (31%), Positives = 57/120 (47%), Gaps = 11/120 (9%) Frame = +2 Query: 122 ASGFVGCISMLILGNEEKNIMALA------LEKENVQNCFT----CAPNLCLNNGVCQEA 271 + GF GC+ +++ E +++A LE + + C C+ N CLN G C Sbjct: 3906 SQGFEGCLDAVVVNEEALDLLAPGKTVAGLLETQALTQCCLHSDYCSQNTCLNGGKCSWT 3965 Query: 272 LTEHGYVCLCAPGFGGNNCDRIGESCRPGLC-GPGKCMNTADSYKCACPVTYTGKNCEVK 448 GYVC C P F G +C++ E+C C G C+ + C CP YTG CE++ Sbjct: 3966 HGA-GYVCKCPPQFSGKHCEQGRENCTFAPCLEGGTCILSPKGASCNCPHPYTGDRCEME 4024 Score = 32.3 bits (70), Expect = 1.1 Identities = 18/51 (35%), Positives = 23/51 (45%) Frame = +2 Query: 212 QNCFTCAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLC 364 +NC T AP CL G C L+ G C C + G+ C+ C G C Sbjct: 3988 ENC-TFAP--CLEGGTC--ILSPKGASCNCPHPYTGDRCEMEARGCSEGHC 4033 >AB177851-1|BAD66829.1| 573|Homo sapiens KIAA0811 splice variant 1 protein. Length = 573 Score = 68.5 bits (160), Expect = 1e-11 Identities = 38/120 (31%), Positives = 57/120 (47%), Gaps = 11/120 (9%) Frame = +2 Query: 122 ASGFVGCISMLILGNEEKNIMALA------LEKENVQNCFT----CAPNLCLNNGVCQEA 271 + GF GC+ +++ E +++A LE + + C C+ N CLN G C Sbjct: 130 SQGFEGCLDAVVVNEEALDLLAPGKTVAGLLETQALTQCCLHSDYCSQNTCLNGGKCSWT 189 Query: 272 LTEHGYVCLCAPGFGGNNCDRIGESCRPGLC-GPGKCMNTADSYKCACPVTYTGKNCEVK 448 GYVC C P F G +C++ E+C C G C+ + C CP YTG CE++ Sbjct: 190 HGA-GYVCKCPPQFSGKHCEQGRENCTFAPCLEGGTCILSPKGASCNCPHPYTGDRCEME 248 Score = 32.3 bits (70), Expect = 1.1 Identities = 18/51 (35%), Positives = 23/51 (45%) Frame = +2 Query: 212 QNCFTCAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLC 364 +NC T AP CL G C L+ G C C + G+ C+ C G C Sbjct: 212 ENC-TFAP--CLEGGTC--ILSPKGASCNCPHPYTGDRCEMEARGCSEGHC 257 >AB011535-1|BAA32463.1| 573|Homo sapiens MEGF1 protein. Length = 573 Score = 68.5 bits (160), Expect = 1e-11 Identities = 38/120 (31%), Positives = 57/120 (47%), Gaps = 11/120 (9%) Frame = +2 Query: 122 ASGFVGCISMLILGNEEKNIMALA------LEKENVQNCFT----CAPNLCLNNGVCQEA 271 + GF GC+ +++ E +++A LE + + C C+ N CLN G C Sbjct: 130 SQGFEGCLDAVVVNEEALDLLAPGKTVAGLLETQALTQCCLHSDYCSQNTCLNGGKCSWT 189 Query: 272 LTEHGYVCLCAPGFGGNNCDRIGESCRPGLC-GPGKCMNTADSYKCACPVTYTGKNCEVK 448 GYVC C P F G +C++ E+C C G C+ + C CP YTG CE++ Sbjct: 190 HGA-GYVCKCPPQFSGKHCEQGRENCTFAPCLEGGTCILSPKGASCNCPHPYTGDRCEME 248 Score = 32.3 bits (70), Expect = 1.1 Identities = 18/51 (35%), Positives = 23/51 (45%) Frame = +2 Query: 212 QNCFTCAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLC 364 +NC T AP CL G C L+ G C C + G+ C+ C G C Sbjct: 212 ENC-TFAP--CLEGGTC--ILSPKGASCNCPHPYTGDRCEMEARGCSEGHC 257 >AL645608-14|CAI15576.1| 270|Homo sapiens agrin protein. Length = 270 Score = 68.1 bits (159), Expect = 2e-11 Identities = 38/102 (37%), Positives = 53/102 (51%), Gaps = 5/102 (4%) Frame = +2 Query: 44 TVLELNQPLYIGGVPDFDQLPIDLAGASGFVGCISMLILGNEEKNIMALALEKENVQN-- 217 TVL L +PLY+GG PDF +L A +SGF G I ++ LG + L + +V + Sbjct: 57 TVLNLKEPLYVGGAPDFSKLARAAAVSSGFDGAIQLVSLGGRQLLTPEHVLRQVDVTSFA 116 Query: 218 ---CFTCAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDR 334 C + + CLN C E YVCLC GF G +C++ Sbjct: 117 GHPCTRASGHPCLNGASC--VPREAAYVCLCPGGFSGPHCEK 156 Score = 31.9 bits (69), Expect = 1.5 Identities = 20/53 (37%), Positives = 27/53 (50%) Frame = +2 Query: 311 FGGNNCDRIGESCRPGLCGPGKCMNTADSYKCACPVTYTGKNCEVKQLIEYPA 469 F G+ C R S P L G C+ +Y C CP ++G +CE K L+E A Sbjct: 115 FAGHPCTRA--SGHPCLNG-ASCVPREAAYVCLCPGGFSGPHCE-KGLVEKSA 163 >AB209873-1|BAD93110.1| 2067|Homo sapiens notch1 preproprotein variant protein. Length = 2067 Score = 68.1 bits (159), Expect = 2e-11 Identities = 30/74 (40%), Positives = 37/74 (50%), Gaps = 1/74 (1%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLC-GPGKCMNTADSYK 403 C N C+N G C++ + GYVC C GF G NC C C G C++ YK Sbjct: 269 CESNPCVNGGTCKDMTS--GYVCTCREGFSGPNCQTNINECASNPCLNQGTCIDDVAGYK 326 Query: 404 CACPVTYTGKNCEV 445 C C + YTG CEV Sbjct: 327 CNCLLPYTGATCEV 340 Score = 65.7 bits (153), Expect = 1e-10 Identities = 29/74 (39%), Positives = 39/74 (52%), Gaps = 2/74 (2%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESC--RPGLCGPGKCMNTADSY 400 C + C N G C + + + + CLC PGF G+ C C +P L G G C + SY Sbjct: 499 CTESSCFNGGTCVDGI--NSFTCLCPPGFTGSYCQHDVNECDSQPCLHG-GTCQDGCGSY 555 Query: 401 KCACPVTYTGKNCE 442 +C CP YTG NC+ Sbjct: 556 RCTCPQGYTGPNCQ 569 Score = 64.5 bits (150), Expect = 2e-10 Identities = 26/77 (33%), Positives = 38/77 (49%) Frame = +2 Query: 215 NCFTCAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLCGPGKCMNTAD 394 N C+ C + G CQ+ ++ Y+C C G G NC+ + C C G C++ D Sbjct: 115 NINECSSQPCRHGGTCQDR--DNAYLCFCLKGTTGPNCEINLDDCASSPCDSGTCLDKID 172 Query: 395 SYKCACPVTYTGKNCEV 445 Y+CAC YTG C + Sbjct: 173 GYECACEPGYTGSMCNI 189 Score = 63.3 bits (147), Expect = 5e-10 Identities = 26/73 (35%), Positives = 37/73 (50%), Gaps = 1/73 (1%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLCGPG-KCMNTADSYK 403 CAP+ C N G C+++ + C+C G+ G C+ C C G C NT Y+ Sbjct: 345 CAPSPCRNGGECRQSEDYESFSCVCPTGWQGQTCEVDINECVLSPCRHGASCQNTHGGYR 404 Query: 404 CACPVTYTGKNCE 442 C C Y+G+NCE Sbjct: 405 CHCQAGYSGRNCE 417 Score = 60.5 bits (140), Expect = 4e-09 Identities = 29/78 (37%), Positives = 41/78 (52%), Gaps = 1/78 (1%) Frame = +2 Query: 215 NCFTCAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLCGPG-KCMNTA 391 N CA + CL+NG C + + E + C C GF G+ C + C C G KC++ Sbjct: 2 NTDECASSPCLHNGRCLDKINE--FQCECPTGFTGHLCQYDVDECASTPCKNGAKCLDGP 59 Query: 392 DSYKCACPVTYTGKNCEV 445 ++Y C C YTG +CEV Sbjct: 60 NTYTCVCTEGYTGTHCEV 77 Score = 60.1 bits (139), Expect = 5e-09 Identities = 30/82 (36%), Positives = 38/82 (46%), Gaps = 5/82 (6%) Frame = +2 Query: 212 QNCFT----CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLCGPG-K 376 +NC T C PN C N G C + + C C PGF G C+ C C G Sbjct: 414 RNCETDIDDCRPNPCHNGGSCTDGINTA--FCDCLPGFRGTFCEEDINECASDPCRNGAN 471 Query: 377 CMNTADSYKCACPVTYTGKNCE 442 C + DSY C CP ++G +CE Sbjct: 472 CTDCVDSYTCTCPAGFSGIHCE 493 Score = 59.3 bits (137), Expect = 8e-09 Identities = 29/80 (36%), Positives = 39/80 (48%), Gaps = 3/80 (3%) Frame = +2 Query: 215 NCFTCAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLC-GPGKCMNTA 391 N CA N CLN G C + + GY C C + G C+ + C P C G+C + Sbjct: 303 NINECASNPCLNQGTCIDDVA--GYKCNCLLPYTGATCEVVLAPCAPSPCRNGGECRQSE 360 Query: 392 D--SYKCACPVTYTGKNCEV 445 D S+ C CP + G+ CEV Sbjct: 361 DYESFSCVCPTGWQGQTCEV 380 Score = 59.3 bits (137), Expect = 8e-09 Identities = 27/74 (36%), Positives = 34/74 (45%), Gaps = 1/74 (1%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLC-GPGKCMNTADSYK 403 C CL+ G CQ+ Y C C G+ G NC + C C GKC T Y+ Sbjct: 537 CDSQPCLHGGTCQDGCGS--YRCTCPQGYTGPNCQNLVHWCDSSPCKNGGKCWQTHTQYR 594 Query: 404 CACPVTYTGKNCEV 445 C CP +TG C+V Sbjct: 595 CECPSGWTGLYCDV 608 Score = 59.3 bits (137), Expect = 8e-09 Identities = 26/74 (35%), Positives = 38/74 (51%), Gaps = 1/74 (1%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLC-GPGKCMNTADSYK 403 C+P+ C N C + L GY C C G+ G NC + C C G C++ ++YK Sbjct: 661 CSPSPCQNGATCTDYLG--GYSCKCVAGYHGVNCSEEIDECLSHPCQNGGTCLDLPNTYK 718 Query: 404 CACPVTYTGKNCEV 445 C+CP G +CE+ Sbjct: 719 CSCPRGTQGVHCEI 732 Score = 58.8 bits (136), Expect = 1e-08 Identities = 24/77 (31%), Positives = 37/77 (48%) Frame = +2 Query: 215 NCFTCAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLCGPGKCMNTAD 394 N CA N C N G C++ + +G+ C C G+ C C C G C ++ + Sbjct: 190 NIDECAGNPCHNGGTCEDGI--NGFTCRCPEGYHDPTCLSEVNECNSNPCVHGACRDSLN 247 Query: 395 SYKCACPVTYTGKNCEV 445 YKC C ++G NC++ Sbjct: 248 GYKCDCDPGWSGTNCDI 264 Score = 58.4 bits (135), Expect = 1e-08 Identities = 26/73 (35%), Positives = 37/73 (50%), Gaps = 1/73 (1%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLC-GPGKCMNTADSYK 403 C N C++ G C+++L +GY C C PG+ G NCD C C G C + Y Sbjct: 232 CNSNPCVH-GACRDSL--NGYKCDCDPGWSGTNCDINNNECESNPCVNGGTCKDMTSGYV 288 Query: 404 CACPVTYTGKNCE 442 C C ++G NC+ Sbjct: 289 CTCREGFSGPNCQ 301 Score = 55.2 bits (127), Expect = 1e-07 Identities = 23/72 (31%), Positives = 34/72 (47%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLCGPGKCMNTADSYKC 406 CA C N C + + Y C+C G+ G +C+ + C P C G C + ++ C Sbjct: 44 CASTPCKNGAKCLDG--PNTYTCVCTEGYTGTHCEVDIDECDPDPCHYGSCKDGVATFTC 101 Query: 407 ACPVTYTGKNCE 442 C YTG +CE Sbjct: 102 LCRPGYTGHHCE 113 Score = 55.2 bits (127), Expect = 1e-07 Identities = 24/70 (34%), Positives = 32/70 (45%), Gaps = 3/70 (4%) Frame = +2 Query: 242 CLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLC---GPGKCMNTADSYKCAC 412 C NNG C + + GY C C PGF G C+ C C G C+ + + C C Sbjct: 750 CFNNGTCVDQVG--GYSCTCPPGFVGERCEGDVNECLSNPCDARGTQNCVQRVNDFHCEC 807 Query: 413 PVTYTGKNCE 442 +TG+ CE Sbjct: 808 RAGHTGRRCE 817 Score = 54.4 bits (125), Expect = 2e-07 Identities = 26/83 (31%), Positives = 39/83 (46%), Gaps = 3/83 (3%) Frame = +2 Query: 239 LCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLCGPG-KCMNTADSYKCACP 415 LC + G+C +A H C C G+ G+ C+ + + C P C G C + Y C C Sbjct: 627 LCQHGGLCVDAGNTHH--CRCQAGYTGSYCEDLVDECSPSPCQNGATCTDYLGGYSCKCV 684 Query: 416 VTYTGKNC--EVKQLIEYPAFTG 478 Y G NC E+ + + +P G Sbjct: 685 AGYHGVNCSEEIDECLSHPCQNG 707 Score = 54.0 bits (124), Expect = 3e-07 Identities = 23/73 (31%), Positives = 34/73 (46%), Gaps = 1/73 (1%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLC-GPGKCMNTADSYK 403 CA + C N C + + Y C C GF G +C+ C C G C++ +S+ Sbjct: 461 CASDPCRNGANCTDCVDS--YTCTCPAGFSGIHCENNTPDCTESSCFNGGTCVDGINSFT 518 Query: 404 CACPVTYTGKNCE 442 C CP +TG C+ Sbjct: 519 CLCPPGFTGSYCQ 531 Score = 50.8 bits (116), Expect = 3e-06 Identities = 24/74 (32%), Positives = 38/74 (51%), Gaps = 1/74 (1%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLC-GPGKCMNTADSYK 403 C P+ C + G C++ + + CLC PG+ G++C+ C C G C + ++Y Sbjct: 82 CDPDPC-HYGSCKDGVAT--FTCLCRPGYTGHHCETNINECSSQPCRHGGTCQDRDNAYL 138 Query: 404 CACPVTYTGKNCEV 445 C C TG NCE+ Sbjct: 139 CFCLKGTTGPNCEI 152 Score = 49.6 bits (113), Expect = 7e-06 Identities = 24/73 (32%), Positives = 33/73 (45%), Gaps = 1/73 (1%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLC-GPGKCMNTADSYK 403 C + C + CQ T GY C C G+ G NC+ + CRP C G C + ++ Sbjct: 385 CVLSPCRHGASCQN--THGGYRCHCQAGYSGRNCETDIDDCRPNPCHNGGSCTDGINTAF 442 Query: 404 CACPVTYTGKNCE 442 C C + G CE Sbjct: 443 CDCLPGFRGTFCE 455 Score = 49.6 bits (113), Expect = 7e-06 Identities = 24/74 (32%), Positives = 32/74 (43%), Gaps = 2/74 (2%) Frame = +2 Query: 227 CAPNLCLNNGVCQEAL-TEHGYVCLCAPGFGGNNCDRIGESCRPGLC-GPGKCMNTADSY 400 C C N G C A T G++C C GF G C+ +C C G C++ S Sbjct: 823 CKGKPCKNGGTCAVASNTARGFICKCPAGFEGATCENDARTCGSLRCLNGGTCISGPRSP 882 Query: 401 KCACPVTYTGKNCE 442 C C +TG C+ Sbjct: 883 TCLCLGPFTGPECQ 896 Score = 47.6 bits (108), Expect = 3e-05 Identities = 27/92 (29%), Positives = 41/92 (44%), Gaps = 3/92 (3%) Frame = +2 Query: 215 NCFTCAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLC-GPGKCMNTA 391 N CA + C ++G C + + GY C C PG+ G+ C+ + C C G C + Sbjct: 153 NLDDCASSPC-DSGTCLDKID--GYECACEPGYTGSMCNINIDECAGNPCHNGGTCEDGI 209 Query: 392 DSYKCACPVTYTGKNC--EVKQLIEYPAFTGS 481 + + C CP Y C EV + P G+ Sbjct: 210 NGFTCRCPEGYHDPTCLSEVNECNSNPCVHGA 241 Score = 45.6 bits (103), Expect = 1e-04 Identities = 34/99 (34%), Positives = 42/99 (42%), Gaps = 5/99 (5%) Frame = +2 Query: 224 TCAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGES-CRPGL-C-GPGKCMNTAD 394 TC CLN G C CLC F G C S C G C G C T++ Sbjct: 863 TCGSLRCLNGGTCISG--PRSPTCLCLGPFTGPECQFPASSPCLGGNPCYNQGTCEPTSE 920 Query: 395 S--YKCACPVTYTGKNCEVKQLIEYPAFTGSA*LAIKPP 505 S Y+C CP + G C + ++Y +F G A I PP Sbjct: 921 SPFYRCLCPAKFNGLLCHI---LDY-SFGGGAGRDIPPP 955 Score = 43.2 bits (97), Expect = 6e-04 Identities = 31/91 (34%), Positives = 40/91 (43%), Gaps = 12/91 (13%) Frame = +2 Query: 206 NVQNCFT-CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESC-----RPG--- 358 N QN C + C N G C + T+ Y C C G+ G CD SC R G Sbjct: 567 NCQNLVHWCDSSPCKNGGKCWQTHTQ--YRCECPSGWTGLYCDVPSVSCEVAAQRQGVDV 624 Query: 359 --LCGPGK-CMNTADSYKCACPVTYTGKNCE 442 LC G C++ +++ C C YTG CE Sbjct: 625 ARLCQHGGLCVDAGNTHHCRCQAGYTGSYCE 655 Score = 43.2 bits (97), Expect = 6e-04 Identities = 23/81 (28%), Positives = 34/81 (41%), Gaps = 9/81 (11%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGL--------C-GPGKC 379 C + C N G C + + Y C C G G +C+ + C P + C G C Sbjct: 699 CLSHPCQNGGTCLDL--PNTYKCSCPRGTQGVHCEINVDDCNPPVDPVSRSPKCFNNGTC 756 Query: 380 MNTADSYKCACPVTYTGKNCE 442 ++ Y C CP + G+ CE Sbjct: 757 VDQVGGYSCTCPPGFVGERCE 777 Score = 41.1 bits (92), Expect = 0.002 Identities = 22/76 (28%), Positives = 29/76 (38%), Gaps = 4/76 (5%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLC-GPGKC---MNTAD 394 C N C G + + C C G G C+ + C+ C G C NTA Sbjct: 783 CLSNPCDARGTQNCVQRVNDFHCECRAGHTGRRCESVINGCKGKPCKNGGTCAVASNTAR 842 Query: 395 SYKCACPVTYTGKNCE 442 + C CP + G CE Sbjct: 843 GFICKCPAGFEGATCE 858 >AB160984-1|BAD08246.1| 1123|Homo sapiens KIAA0811 protein protein. Length = 1123 Score = 68.1 bits (159), Expect = 2e-11 Identities = 38/118 (32%), Positives = 56/118 (47%), Gaps = 11/118 (9%) Frame = +2 Query: 128 GFVGCISMLILGNEEKNIMALA------LEKENVQNCFT----CAPNLCLNNGVCQEALT 277 GF GC+ +++ E +++A LE + + C C+ N CLN G C Sbjct: 682 GFEGCLDAVVVNEEALDLLAPGKTVAGLLETQALTQCCLHSDYCSQNTCLNGGKCSWTHG 741 Query: 278 EHGYVCLCAPGFGGNNCDRIGESCRPGLC-GPGKCMNTADSYKCACPVTYTGKNCEVK 448 GYVC C P F G +C++ E+C C G C+ + C CP YTG CE++ Sbjct: 742 A-GYVCKCPPQFSGKHCEQGRENCTFAPCLEGGTCILSPKGASCNCPHPYTGDRCEME 798 Score = 32.3 bits (70), Expect = 1.1 Identities = 18/51 (35%), Positives = 23/51 (45%) Frame = +2 Query: 212 QNCFTCAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLC 364 +NC T AP CL G C L+ G C C + G+ C+ C G C Sbjct: 762 ENC-TFAP--CLEGGTC--ILSPKGASCNCPHPYTGDRCEMEARGCSEGHC 807 >AB209447-1|BAD92684.1| 1289|Homo sapiens Notch homolog 3 variant protein. Length = 1289 Score = 67.3 bits (157), Expect = 3e-11 Identities = 30/72 (41%), Positives = 36/72 (50%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLCGPGKCMNTADSYKC 406 CA C N C + GY C CA GF G CDR + C P C G+C++ S+ C Sbjct: 514 CASTPCRNGAKCVDQ--PDGYECRCAEGFEGTLCDRNVDDCSPDPCHHGRCVDGIASFSC 571 Query: 407 ACPVTYTGKNCE 442 AC YTG CE Sbjct: 572 ACAPGYTGTRCE 583 Score = 67.3 bits (157), Expect = 3e-11 Identities = 28/67 (41%), Positives = 35/67 (52%) Frame = +2 Query: 242 CLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLCGPGKCMNTADSYKCACPVT 421 CLN G CQ+ + + C C PGF G C R + C CGPG C + S+ C CP Sbjct: 809 CLNGGSCQDGVGS--FSCSCLPGFAGPRCARDVDECLSNPCGPGTCTDHVASFTCTCPPG 866 Query: 422 YTGKNCE 442 Y G +CE Sbjct: 867 YGGFHCE 873 Score = 65.3 bits (152), Expect = 1e-10 Identities = 30/79 (37%), Positives = 43/79 (54%), Gaps = 1/79 (1%) Frame = +2 Query: 212 QNCFTCAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLC-GPGKCMNT 388 +N C+P+ C ++G C + + + C CAPG+ G C+ + CR C GKC++ Sbjct: 547 RNVDDCSPDPC-HHGRCVDGIAS--FSCACAPGYTGTRCESQVDECRSQPCRHGGKCLDL 603 Query: 389 ADSYKCACPVTYTGKNCEV 445 D Y C CP TG NCEV Sbjct: 604 VDKYLCRCPSGTTGVNCEV 622 Score = 63.7 bits (148), Expect = 4e-10 Identities = 27/72 (37%), Positives = 40/72 (55%), Gaps = 1/72 (1%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLC-GPGKCMNTADSYK 403 CAP+ C N G C+++ + Y C C PGF G NC+ + C C G C++ ++Y Sbjct: 204 CAPSPCRNGGTCRQS-GDLTYDCACLPGFEGQNCEVNVDDCPGHRCLNGGTCVDGVNTYN 262 Query: 404 CACPVTYTGKNC 439 C CP +TG+ C Sbjct: 263 CQCPPEWTGQFC 274 Score = 58.0 bits (134), Expect = 2e-08 Identities = 27/75 (36%), Positives = 35/75 (46%), Gaps = 3/75 (4%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGL--CGP-GKCMNTADS 397 C N C + +C +C C PGF G CD+ + C G C G+C+NT S Sbjct: 358 CVSNPCHEDAICDTNPVNGRAICTCPPGFTGGACDQDVDECSIGANPCEHLGRCVNTQGS 417 Query: 398 YKCACPVTYTGKNCE 442 + C C YTG CE Sbjct: 418 FLCQCGRGYTGPRCE 432 Score = 58.0 bits (134), Expect = 2e-08 Identities = 25/74 (33%), Positives = 39/74 (52%), Gaps = 2/74 (2%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESC--RPGLCGPGKCMNTADSY 400 C+P+ C N G C + + + + CLC PG+ G +C + C RP L G G C + Sbjct: 879 CSPSSCFNGGTCVDGV--NSFSCLCRPGYTGAHCQHEADPCLSRPCLHG-GVCSAAHPGF 935 Query: 401 KCACPVTYTGKNCE 442 +C C ++TG C+ Sbjct: 936 RCTCLESFTGPQCQ 949 Score = 57.6 bits (133), Expect = 3e-08 Identities = 28/78 (35%), Positives = 39/78 (50%), Gaps = 6/78 (7%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCD------RIGESCRPGLCGPGKCMNT 388 C + C + C + ++C C PG+ G +C R+GE CR G G C+NT Sbjct: 126 CLSSPCAHGARCSVG-PDGRFLCSCPPGYQGRSCRSDVDECRVGEPCRHG----GTCLNT 180 Query: 389 ADSYKCACPVTYTGKNCE 442 S++C CP YTG CE Sbjct: 181 PGSFRCQCPAGYTGPLCE 198 Score = 57.6 bits (133), Expect = 3e-08 Identities = 29/92 (31%), Positives = 42/92 (45%), Gaps = 5/92 (5%) Frame = +2 Query: 242 CLNNGVCQEALTEH--GYVCLCAPGFGGNNCDRIGESCRPGLC-GPGKCMNTADSYKCAC 412 CL+N T+H + C C PG+GG +C++ C P C G C++ +S+ C C Sbjct: 842 CLSNPCGPGTCTDHVASFTCTCPPGYGGFHCEQDLPDCSPSSCFNGGTCVDGVNSFSCLC 901 Query: 413 PVTYTGKNC--EVKQLIEYPAFTGSA*LAIKP 502 YTG +C E + P G A P Sbjct: 902 RPGYTGAHCQHEADPCLSRPCLHGGVCSAAHP 933 Score = 57.2 bits (132), Expect = 3e-08 Identities = 24/73 (32%), Positives = 38/73 (52%), Gaps = 1/73 (1%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLCGPG-KCMNTADSYK 403 C + C+N GVC++ + +G+ C C GF G+ C + C C G KC++ D Y+ Sbjct: 476 CQSSPCVNGGVCKDRV--NGFSCTCPSGFSGSTCQLDVDECASTPCRNGAKCVDQPDGYE 533 Query: 404 CACPVTYTGKNCE 442 C C + G C+ Sbjct: 534 CRCAEGFEGTLCD 546 Score = 54.8 bits (126), Expect = 2e-07 Identities = 24/76 (31%), Positives = 37/76 (48%), Gaps = 1/76 (1%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLC-GPGKCMNTADSYK 403 C C + G C+ + GY+C C PG+ G+NC+ + C C G C++ Y Sbjct: 1039 CLAQPCQHGGTCRGYMG--GYMCECLPGYNGDNCEDDVDECASQPCQHGGSCIDLVARYL 1096 Query: 404 CACPVTYTGKNCEVKQ 451 C+CP G CE+ + Sbjct: 1097 CSCPPGTLGVLCEINE 1112 Score = 51.2 bits (117), Expect = 2e-06 Identities = 27/85 (31%), Positives = 39/85 (45%), Gaps = 4/85 (4%) Frame = +2 Query: 197 EKENVQ-NCFTCAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCR--PGLC- 364 E +N + N C + CLN G C + + Y C C P + G C + C+ P C Sbjct: 232 EGQNCEVNVDDCPGHRCLNGGTCVDGVNT--YNCQCPPEWTGQFCTEDVDECQLQPNACH 289 Query: 365 GPGKCMNTADSYKCACPVTYTGKNC 439 G C NT + C C +TG++C Sbjct: 290 NGGTCFNTLGGHSCVCVNGWTGESC 314 Score = 50.8 bits (116), Expect = 3e-06 Identities = 27/80 (33%), Positives = 37/80 (46%), Gaps = 8/80 (10%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGL---CGP-----GKCM 382 CA C + G C + + Y+C C PG G C+ + C PG GP G C+ Sbjct: 1077 CASQPCQHGGSCIDLVAR--YLCSCPPGTLGVLCEINEDDCGPGPPLDSGPRCLHNGTCV 1134 Query: 383 NTADSYKCACPVTYTGKNCE 442 + ++C CP YTG CE Sbjct: 1135 DLVGGFRCTCPPGYTGLRCE 1154 Score = 50.4 bits (115), Expect = 4e-06 Identities = 25/75 (33%), Positives = 34/75 (45%), Gaps = 4/75 (5%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHG---YVCLCAPGFGGNNCDRIGESCRPGLCGPG-KCMNTAD 394 C C + G C+ + G + C CA F G C+R+ SCR C G C T Sbjct: 1201 CESQPCQHGGQCRPSPGPGGGLTFTCHCAQPFWGPRCERVARSCRELQCPVGVPCQQTPR 1260 Query: 395 SYKCACPVTYTGKNC 439 +CACP +G +C Sbjct: 1261 GPRCACPPGLSGPSC 1275 Score = 50.0 bits (114), Expect = 5e-06 Identities = 25/77 (32%), Positives = 38/77 (49%), Gaps = 1/77 (1%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLC-GPGKCMNTADSYK 403 C CL+ GVC A G+ C C F G C + + C C G+C+ T +Y Sbjct: 917 CLSRPCLHGGVCSAA--HPGFRCTCLESFTGPQCQTLVDWCSRQPCQNGGRCVQTG-AY- 972 Query: 404 CACPVTYTGKNCEVKQL 454 C CP ++G+ C+++ L Sbjct: 973 CLCPPGWSGRLCDIRSL 989 Score = 49.6 bits (113), Expect = 7e-06 Identities = 19/74 (25%), Positives = 34/74 (45%), Gaps = 1/74 (1%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLC-GPGKCMNTADSYK 403 C C N C + + + + C+C GF G C+ + C+ C G C + + + Sbjct: 438 CLSGPCRNQATCLDRIGQ--FTCICMAGFTGTYCEVDIDECQSSPCVNGGVCKDRVNGFS 495 Query: 404 CACPVTYTGKNCEV 445 C CP ++G C++ Sbjct: 496 CTCPSGFSGSTCQL 509 Score = 49.6 bits (113), Expect = 7e-06 Identities = 24/68 (35%), Positives = 34/68 (50%), Gaps = 1/68 (1%) Frame = +2 Query: 215 NCFTCAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLCGP-GKCMNTA 391 N CA N C GVC++ + Y C+C PGF G C+ C CG G C++ Sbjct: 623 NIDDCASNPC-TFGVCRDGINR--YDCVCQPGFTGPLCNVEINECASSPCGEGGSCVDGE 679 Query: 392 DSYKCACP 415 + ++C CP Sbjct: 680 NGFRCLCP 687 Score = 49.2 bits (112), Expect = 9e-06 Identities = 27/84 (32%), Positives = 37/84 (44%), Gaps = 2/84 (2%) Frame = +2 Query: 200 KENVQNCFTCAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLC-GPGK 376 + +V C P C + G C T + C C G+ G C+ C P C G Sbjct: 159 RSDVDECRVGEP--CRHGGTCLN--TPGSFRCQCPAGYTGPLCENPAVPCAPSPCRNGGT 214 Query: 377 CMNTAD-SYKCACPVTYTGKNCEV 445 C + D +Y CAC + G+NCEV Sbjct: 215 CRQSGDLTYDCACLPGFEGQNCEV 238 Score = 47.6 bits (108), Expect = 3e-05 Identities = 22/74 (29%), Positives = 33/74 (44%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLCGPGKCMNTADSYKC 406 C C + G C + + + Y+C C G G NC+ + C C G C + + Y C Sbjct: 589 CRSQPCRHGGKCLDLVDK--YLCRCPSGTTGVNCEVNIDDCASNPCTFGVCRDGINRYDC 646 Query: 407 ACPVTYTGKNCEVK 448 C +TG C V+ Sbjct: 647 VCQPGFTGPLCNVE 660 Score = 47.2 bits (107), Expect = 4e-05 Identities = 23/76 (30%), Positives = 37/76 (48%), Gaps = 3/76 (3%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDR--IGESCRPGLC-GPGKCMNTADS 397 CA C ++G+C +A G+ C+C PG+ G C + ++C C G C + Sbjct: 702 CAHEPC-SHGICYDA--PGGFRCVCEPGWSGPRCSQSLARDACESQPCRAGGTCSSDGMG 758 Query: 398 YKCACPVTYTGKNCEV 445 + C CP G+ CE+ Sbjct: 759 FHCTCPPGVQGRQCEL 774 Score = 47.2 bits (107), Expect = 4e-05 Identities = 28/83 (33%), Positives = 36/83 (43%), Gaps = 11/83 (13%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPG----------LC-GPG 373 C+ C N G C + G CLC PG+ G CD CR LC G Sbjct: 955 CSRQPCQNGGRCVQT----GAYCLCPPGWSGRLCDIRSLPCREAAAQIGVRLEQLCQAGG 1010 Query: 374 KCMNTADSYKCACPVTYTGKNCE 442 +C++ S+ C CP TG +CE Sbjct: 1011 QCVDEDSSHYCVCPEGRTGSHCE 1033 Score = 47.2 bits (107), Expect = 4e-05 Identities = 21/71 (29%), Positives = 34/71 (47%), Gaps = 4/71 (5%) Frame = +2 Query: 242 CLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLCGPG---KCM-NTADSYKCA 409 CL+NG C + + G+ C C PG+ G C+ CR G C C+ + ++C Sbjct: 1127 CLHNGTCVDLVG--GFRCTCPPGYTGLRCEADINECRSGACHAAHTRDCLQDPGGGFRCL 1184 Query: 410 CPVTYTGKNCE 442 C ++G C+ Sbjct: 1185 CHAGFSGPRCQ 1195 Score = 46.0 bits (104), Expect = 8e-05 Identities = 23/82 (28%), Positives = 36/82 (43%), Gaps = 1/82 (1%) Frame = +2 Query: 203 ENVQNCFTCAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLC-GPGKC 379 ++V C + N C + G C T+ ++C C G+ G C+ C G C C Sbjct: 393 QDVDEC-SIGANPCEHLGRCVN--TQGSFLCQCGRGYTGPRCETDVNECLSGPCRNQATC 449 Query: 380 MNTADSYKCACPVTYTGKNCEV 445 ++ + C C +TG CEV Sbjct: 450 LDRIGQFTCICMAGFTGTYCEV 471 Score = 45.2 bits (102), Expect = 1e-04 Identities = 23/73 (31%), Positives = 35/73 (47%), Gaps = 5/73 (6%) Frame = +2 Query: 242 CLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLC-GPGKCMNTADS----YKC 406 C N G C + L CLC PG+ G C ++ + C G C G G C ++ + + C Sbjct: 52 CANGGRCTQ-LPSREAACLCPPGWVGERC-QLEDPCHSGPCAGRGVCQSSVVAGTARFSC 109 Query: 407 ACPVTYTGKNCEV 445 CP + G +C + Sbjct: 110 RCPRGFRGPDCSL 122 Score = 44.4 bits (100), Expect = 3e-04 Identities = 21/71 (29%), Positives = 30/71 (42%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLCGPGKCMNTADSYKC 406 CA + C G C + E+G+ CLC PG C C C G C + ++C Sbjct: 664 CASSPCGEGGSCVDG--ENGFRCLCPPGSLPPLCLPPSHPCAHEPCSHGICYDAPGGFRC 721 Query: 407 ACPVTYTGKNC 439 C ++G C Sbjct: 722 VCEPGWSGPRC 732 Score = 43.2 bits (97), Expect = 6e-04 Identities = 22/69 (31%), Positives = 30/69 (43%), Gaps = 1/69 (1%) Frame = +2 Query: 239 LCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLC-GPGKCMNTADSYKCACP 415 LC G C + + H C+C G G++C++ + C C G C Y C C Sbjct: 1005 LCQAGGQCVDEDSSH--YCVCPEGRTGSHCEQEVDPCLAQPCQHGGTCRGYMGGYMCECL 1062 Query: 416 VTYTGKNCE 442 Y G NCE Sbjct: 1063 PGYNGDNCE 1071 Score = 34.3 bits (75), Expect = 0.27 Identities = 17/59 (28%), Positives = 22/59 (37%), Gaps = 6/59 (10%) Frame = +2 Query: 284 GYVCLCAPGFGGNNCDRIGESCRP------GLCGPGKCMNTADSYKCACPVTYTGKNCE 442 G+ CLC GF G C + C G C P ++ C C + G CE Sbjct: 1180 GFRCLCHAGFSGPRCQTVLSPCESQPCQHGGQCRPSPGPGGGLTFTCHCAQPFWGPRCE 1238 >BC133013-1|AAI33014.1| 594|Homo sapiens EGF-like-domain, multiple 11 protein. Length = 594 Score = 66.1 bits (154), Expect = 7e-11 Identities = 32/82 (39%), Positives = 42/82 (51%), Gaps = 4/82 (4%) Frame = +2 Query: 212 QNCFTCAPNLCLNNGVC---QEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLCGPGKCM 382 Q C+ C NNG C +E E Y C+C P F G NC I C+P +C G C Sbjct: 212 QELDACSFKPCKNNGSCINKRENWDEQAYECVCHPPFTGKNCSEIIGQCQPHVCFHGNCS 271 Query: 383 N-TADSYKCACPVTYTGKNCEV 445 N T++S+ C C ++G CEV Sbjct: 272 NITSNSFICECDEQFSGPFCEV 293 Score = 45.6 bits (103), Expect = 1e-04 Identities = 23/72 (31%), Positives = 32/72 (44%), Gaps = 6/72 (8%) Frame = +2 Query: 242 CLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLC-GPGKCMNTAD-----SYK 403 C +G C Y C C P F G C + ++C C G C+N + +Y+ Sbjct: 183 CSGHGKCLSEAWSKTYSCHCQPPFSGKYCQEL-DACSFKPCKNNGSCINKRENWDEQAYE 241 Query: 404 CACPVTYTGKNC 439 C C +TGKNC Sbjct: 242 CVCHPPFTGKNC 253 Score = 38.3 bits (85), Expect = 0.017 Identities = 21/73 (28%), Positives = 35/73 (47%), Gaps = 1/73 (1%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLCGP-GKCMNTADSYK 403 C P++C + G C +T + ++C C F G C+ + C L G C N++ +Y Sbjct: 260 CQPHVCFH-GNCSN-ITSNSFICECDEQFSGPFCEVSAKPCVSLLFWKRGICPNSSSAYT 317 Query: 404 CACPVTYTGKNCE 442 CP + +N E Sbjct: 318 YECPKGSSSQNGE 330 Score = 36.7 bits (81), Expect = 0.052 Identities = 18/52 (34%), Positives = 23/52 (44%), Gaps = 1/52 (1%) Frame = +2 Query: 290 VCLCAPGFGGNNCDRIGESCRP-GLCGPGKCMNTADSYKCACPVTYTGKNCE 442 +C+C+P F C I SC L C Y C+C +T KNCE Sbjct: 355 MCICSPIFTDLLCKSIQTSCESFPLRNNATCKKCEKDYPCSCISGFTEKNCE 406 Score = 31.1 bits (67), Expect = 2.6 Identities = 18/67 (26%), Positives = 25/67 (37%), Gaps = 3/67 (4%) Frame = +2 Query: 248 NNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCR---PGLCGPGKCMNTADSYKCACPV 418 NN C++ E Y C C GF NC++ + C+ C N +K C Sbjct: 381 NNATCKKC--EKDYPCSCISGFTEKNCEKAIDHCKLLSINCLNEEWCFNIIGRFKYVCIP 438 Query: 419 TYTGKNC 439 T C Sbjct: 439 GCTKNPC 445 >BC133011-1|AAI33012.1| 594|Homo sapiens EGF-like-domain, multiple 11 protein. Length = 594 Score = 66.1 bits (154), Expect = 7e-11 Identities = 32/82 (39%), Positives = 42/82 (51%), Gaps = 4/82 (4%) Frame = +2 Query: 212 QNCFTCAPNLCLNNGVC---QEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLCGPGKCM 382 Q C+ C NNG C +E E Y C+C P F G NC I C+P +C G C Sbjct: 212 QELDACSFKPCKNNGSCINKRENWDEQAYECVCHPPFTGKNCSEIIGQCQPHVCFHGNCS 271 Query: 383 N-TADSYKCACPVTYTGKNCEV 445 N T++S+ C C ++G CEV Sbjct: 272 NITSNSFICECDEQFSGPFCEV 293 Score = 45.6 bits (103), Expect = 1e-04 Identities = 23/72 (31%), Positives = 32/72 (44%), Gaps = 6/72 (8%) Frame = +2 Query: 242 CLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLC-GPGKCMNTAD-----SYK 403 C +G C Y C C P F G C + ++C C G C+N + +Y+ Sbjct: 183 CSGHGKCLSEAWSKTYSCHCQPPFSGKYCQEL-DACSFKPCKNNGSCINKRENWDEQAYE 241 Query: 404 CACPVTYTGKNC 439 C C +TGKNC Sbjct: 242 CVCHPPFTGKNC 253 Score = 38.3 bits (85), Expect = 0.017 Identities = 21/73 (28%), Positives = 35/73 (47%), Gaps = 1/73 (1%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLCGP-GKCMNTADSYK 403 C P++C + G C +T + ++C C F G C+ + C L G C N++ +Y Sbjct: 260 CQPHVCFH-GNCSN-ITSNSFICECDEQFSGPFCEVSAKPCVSLLFWKRGICPNSSSAYT 317 Query: 404 CACPVTYTGKNCE 442 CP + +N E Sbjct: 318 YECPKGSSSQNGE 330 Score = 36.7 bits (81), Expect = 0.052 Identities = 18/52 (34%), Positives = 23/52 (44%), Gaps = 1/52 (1%) Frame = +2 Query: 290 VCLCAPGFGGNNCDRIGESCRP-GLCGPGKCMNTADSYKCACPVTYTGKNCE 442 +C+C+P F C I SC L C Y C+C +T KNCE Sbjct: 355 MCICSPIFTDLLCKSIQTSCESFPLRNNATCKKCEKDYPCSCISGFTEKNCE 406 Score = 31.1 bits (67), Expect = 2.6 Identities = 18/67 (26%), Positives = 25/67 (37%), Gaps = 3/67 (4%) Frame = +2 Query: 248 NNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCR---PGLCGPGKCMNTADSYKCACPV 418 NN C++ E Y C C GF NC++ + C+ C N +K C Sbjct: 381 NNATCKKC--EKDYPCSCISGFTEKNCEKAIDHCKLLSINCLNEEWCFNIIGRFKYVCIP 438 Query: 419 TYTGKNC 439 T C Sbjct: 439 GCTKNPC 445 >BC106950-1|AAI06951.1| 685|Homo sapiens delta-like 4 (Drosophila) protein. Length = 685 Score = 66.1 bits (154), Expect = 7e-11 Identities = 32/77 (41%), Positives = 39/77 (50%), Gaps = 3/77 (3%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLC-GPGKC--MNTADS 397 C N C N G C++ E GY CLC PG+ G +C+ SC C G C N + Sbjct: 328 CDSNPCRNGGSCKDQ--EDGYHCLCPPGYYGLHCEHSTLSCADSPCFNGGSCRERNQGAN 385 Query: 398 YKCACPVTYTGKNCEVK 448 Y C CP +TG NCE K Sbjct: 386 YACECPPNFTGSNCEKK 402 Score = 64.1 bits (149), Expect = 3e-10 Identities = 27/75 (36%), Positives = 38/75 (50%), Gaps = 1/75 (1%) Frame = +2 Query: 224 TCAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLC-GPGKCMNTADSY 400 +CA + C N G C+E Y C C P F G+NC++ + C C G+C+N S Sbjct: 365 SCADSPCFNGGSCRERNQGANYACECPPNFTGSNCEKKVDRCTSNPCANGGQCLNRGPSR 424 Query: 401 KCACPVTYTGKNCEV 445 C C +TG CE+ Sbjct: 425 MCRCRPGFTGTYCEL 439 Score = 56.0 bits (129), Expect = 8e-08 Identities = 27/84 (32%), Positives = 36/84 (42%), Gaps = 3/84 (3%) Frame = +2 Query: 242 CLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLC-GPGKCMNTADSYKCACPV 418 C N C + + Y C C PG+ G +C+ C C G C + D Y C CP Sbjct: 294 CKNGATCSNS-GQRSYTCTCRPGYTGVDCELELSECDSNPCRNGGSCKDQEDGYHCLCPP 352 Query: 419 TYTGKNCEVKQL--IEYPAFTGSA 484 Y G +CE L + P F G + Sbjct: 353 GYYGLHCEHSTLSCADSPCFNGGS 376 Score = 54.0 bits (124), Expect = 3e-07 Identities = 25/79 (31%), Positives = 34/79 (43%), Gaps = 1/79 (1%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLCGPG-KCMNTADSYK 403 C N C N G C +C C PGF G C+ C C G C + + Sbjct: 406 CTSNPCANGGQCLNRGPSR--MCRCRPGFTGTYCELHVSDCARNPCAHGGTCHDLENGLM 463 Query: 404 CACPVTYTGKNCEVKQLIE 460 C CP ++G+ CEV+ I+ Sbjct: 464 CTCPAGFSGRRCEVRTSID 482 Score = 49.6 bits (113), Expect = 7e-06 Identities = 25/77 (32%), Positives = 36/77 (46%), Gaps = 5/77 (6%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCD-RIG-ESCRPGLC-GPGKCMN--TA 391 CA N C + G C + E+G +C C GF G C+ R ++C C C + Sbjct: 444 CARNPCAHGGTCHDL--ENGLMCTCPAGFSGRRCEVRTSIDACASSPCFNRATCYTDLST 501 Query: 392 DSYKCACPVTYTGKNCE 442 D++ C CP + G CE Sbjct: 502 DTFVCNCPYGFVGSRCE 518 Score = 44.0 bits (99), Expect = 3e-04 Identities = 24/74 (32%), Positives = 34/74 (45%), Gaps = 3/74 (4%) Frame = +2 Query: 236 NLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESC-RPGLCGPG-KCMNTAD-SYKC 406 N C+ + C+ + C C G+GG CD+ C C G C N+ SY C Sbjct: 251 NECIPHNGCRHGTCSTPWQCTCDEGWGGLFCDQDLNYCTHHSPCKNGATCSNSGQRSYTC 310 Query: 407 ACPVTYTGKNCEVK 448 C YTG +CE++ Sbjct: 311 TCRPGYTGVDCELE 324 Score = 31.1 bits (67), Expect = 2.6 Identities = 17/54 (31%), Positives = 22/54 (40%), Gaps = 3/54 (5%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRI--GESCRPGLCG-PGKC 379 C +CL+ Q CLC PG+ G C+ CR G C P +C Sbjct: 217 CQQPICLSGCHEQNGYCSKPAECLCRPGWQGRLCNECIPHNGCRHGTCSTPWQC 270 >AY358894-1|AAQ89253.1| 685|Homo sapiens DLL4 protein. Length = 685 Score = 66.1 bits (154), Expect = 7e-11 Identities = 32/77 (41%), Positives = 39/77 (50%), Gaps = 3/77 (3%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLC-GPGKC--MNTADS 397 C N C N G C++ E GY CLC PG+ G +C+ SC C G C N + Sbjct: 328 CDSNPCRNGGSCKDQ--EDGYHCLCPPGYYGLHCEHSTLSCADSPCFNGGSCRERNQGAN 385 Query: 398 YKCACPVTYTGKNCEVK 448 Y C CP +TG NCE K Sbjct: 386 YACECPPNFTGSNCEKK 402 Score = 64.1 bits (149), Expect = 3e-10 Identities = 27/75 (36%), Positives = 38/75 (50%), Gaps = 1/75 (1%) Frame = +2 Query: 224 TCAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLC-GPGKCMNTADSY 400 +CA + C N G C+E Y C C P F G+NC++ + C C G+C+N S Sbjct: 365 SCADSPCFNGGSCRERNQGANYACECPPNFTGSNCEKKVDRCTSNPCANGGQCLNRGPSR 424 Query: 401 KCACPVTYTGKNCEV 445 C C +TG CE+ Sbjct: 425 MCRCRPGFTGTYCEL 439 Score = 56.0 bits (129), Expect = 8e-08 Identities = 27/84 (32%), Positives = 36/84 (42%), Gaps = 3/84 (3%) Frame = +2 Query: 242 CLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLC-GPGKCMNTADSYKCACPV 418 C N C + + Y C C PG+ G +C+ C C G C + D Y C CP Sbjct: 294 CKNGATCSNS-GQRSYTCTCRPGYTGVDCELELSECDSNPCRNGGSCKDQEDGYHCLCPP 352 Query: 419 TYTGKNCEVKQL--IEYPAFTGSA 484 Y G +CE L + P F G + Sbjct: 353 GYYGLHCEHSTLSCADSPCFNGGS 376 Score = 54.0 bits (124), Expect = 3e-07 Identities = 25/79 (31%), Positives = 34/79 (43%), Gaps = 1/79 (1%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLCGPG-KCMNTADSYK 403 C N C N G C +C C PGF G C+ C C G C + + Sbjct: 406 CTSNPCANGGQCLNRGPSR--MCRCRPGFTGTYCELHVSDCARNPCAHGGTCHDLENGLM 463 Query: 404 CACPVTYTGKNCEVKQLIE 460 C CP ++G+ CEV+ I+ Sbjct: 464 CTCPAGFSGRRCEVRTSID 482 Score = 49.6 bits (113), Expect = 7e-06 Identities = 25/77 (32%), Positives = 36/77 (46%), Gaps = 5/77 (6%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCD-RIG-ESCRPGLC-GPGKCMN--TA 391 CA N C + G C + E+G +C C GF G C+ R ++C C C + Sbjct: 444 CARNPCAHGGTCHDL--ENGLMCTCPAGFSGRRCEVRTSIDACASSPCFNRATCYTDLST 501 Query: 392 DSYKCACPVTYTGKNCE 442 D++ C CP + G CE Sbjct: 502 DTFVCNCPYGFVGSRCE 518 Score = 44.0 bits (99), Expect = 3e-04 Identities = 24/74 (32%), Positives = 34/74 (45%), Gaps = 3/74 (4%) Frame = +2 Query: 236 NLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESC-RPGLCGPG-KCMNTAD-SYKC 406 N C+ + C+ + C C G+GG CD+ C C G C N+ SY C Sbjct: 251 NECIPHNGCRHGTCSTPWQCTCDEGWGGLFCDQDLNYCTHHSPCKNGATCSNSGQRSYTC 310 Query: 407 ACPVTYTGKNCEVK 448 C YTG +CE++ Sbjct: 311 TCRPGYTGVDCELE 324 Score = 31.1 bits (67), Expect = 2.6 Identities = 17/54 (31%), Positives = 22/54 (40%), Gaps = 3/54 (5%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRI--GESCRPGLCG-PGKC 379 C +CL+ Q CLC PG+ G C+ CR G C P +C Sbjct: 217 CQQPICLSGCHEQNGYCSKPAECLCRPGWQGRLCNECIPHNGCRHGTCSTPWQC 270 >AY358133-1|AAQ88500.1| 594|Homo sapiens TDKS9424 protein. Length = 594 Score = 66.1 bits (154), Expect = 7e-11 Identities = 32/82 (39%), Positives = 42/82 (51%), Gaps = 4/82 (4%) Frame = +2 Query: 212 QNCFTCAPNLCLNNGVC---QEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLCGPGKCM 382 Q C+ C NNG C +E E Y C+C P F G NC I C+P +C G C Sbjct: 212 QELDACSFKPCKNNGSCINKRENWDEQAYECVCHPPFTGKNCSEIIGQCQPHVCFHGNCS 271 Query: 383 N-TADSYKCACPVTYTGKNCEV 445 N T++S+ C C ++G CEV Sbjct: 272 NITSNSFICECDEQFSGPFCEV 293 Score = 45.6 bits (103), Expect = 1e-04 Identities = 23/72 (31%), Positives = 32/72 (44%), Gaps = 6/72 (8%) Frame = +2 Query: 242 CLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLC-GPGKCMNTAD-----SYK 403 C +G C Y C C P F G C + ++C C G C+N + +Y+ Sbjct: 183 CSGHGKCLSEAWSKTYSCHCQPPFSGKYCQEL-DACSFKPCKNNGSCINKRENWDEQAYE 241 Query: 404 CACPVTYTGKNC 439 C C +TGKNC Sbjct: 242 CVCHPPFTGKNC 253 Score = 38.3 bits (85), Expect = 0.017 Identities = 21/73 (28%), Positives = 35/73 (47%), Gaps = 1/73 (1%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLCGP-GKCMNTADSYK 403 C P++C + G C +T + ++C C F G C+ + C L G C N++ +Y Sbjct: 260 CQPHVCFH-GNCSN-ITSNSFICECDEQFSGPFCEVSAKPCVSLLFWKRGICPNSSSAYT 317 Query: 404 CACPVTYTGKNCE 442 CP + +N E Sbjct: 318 YECPKGSSSQNGE 330 Score = 36.7 bits (81), Expect = 0.052 Identities = 18/52 (34%), Positives = 23/52 (44%), Gaps = 1/52 (1%) Frame = +2 Query: 290 VCLCAPGFGGNNCDRIGESCRP-GLCGPGKCMNTADSYKCACPVTYTGKNCE 442 +C+C+P F C I SC L C Y C+C +T KNCE Sbjct: 355 MCICSPIFTDLLCKSIQTSCESFPLRNNATCKKCEKDYPCSCISGFTEKNCE 406 Score = 31.1 bits (67), Expect = 2.6 Identities = 18/67 (26%), Positives = 25/67 (37%), Gaps = 3/67 (4%) Frame = +2 Query: 248 NNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCR---PGLCGPGKCMNTADSYKCACPV 418 NN C++ E Y C C GF NC++ + C+ C N +K C Sbjct: 381 NNATCKKC--EKDYPCSCISGFTEKNCEKAIDHCKLLSINCLNEEWCFNIIGRFKYVCIP 438 Query: 419 TYTGKNC 439 T C Sbjct: 439 GCTKNPC 445 >AY243503-1|AAQ89957.1| 3574|Homo sapiens selectin-like protein protein. Length = 3574 Score = 66.1 bits (154), Expect = 7e-11 Identities = 28/74 (37%), Positives = 42/74 (56%), Gaps = 1/74 (1%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLCGPG-KCMNTADSYK 403 C N CLNN VC++ + G++C C PGF G C + + C C G C + A+S++ Sbjct: 1311 CQSNPCLNNAVCEDQVG--GFLCKCPPGFLGTRCGKNVDECLSQPCKNGATCKDGANSFR 1368 Query: 404 CACPVTYTGKNCEV 445 C C +TG +CE+ Sbjct: 1369 CLCAAGFTGSHCEL 1382 Score = 61.7 bits (143), Expect = 2e-09 Identities = 29/73 (39%), Positives = 37/73 (50%), Gaps = 1/73 (1%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLC-GPGKCMNTADSYK 403 C N C N+G CQ+ GYVCLC G+ G C+ + C P C G C + + Sbjct: 1197 CFFNPCHNSGTCQQL--GRGYVCLCPLGYTGLKCETDIDECSPLPCLNNGVCKDLVGEFI 1254 Query: 404 CACPVTYTGKNCE 442 C CP YTG+ CE Sbjct: 1255 CECPSGYTGQRCE 1267 Score = 57.6 bits (133), Expect = 3e-08 Identities = 25/81 (30%), Positives = 40/81 (49%), Gaps = 1/81 (1%) Frame = +2 Query: 212 QNCFTCAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLC-GPGKCMNT 388 +N C C N C++ + + CLCA GF G++C+ C+ C C++ Sbjct: 1344 KNVDECLSQPCKNGATCKDGA--NSFRCLCAAGFTGSHCELNINECQSNPCRNQATCVDE 1401 Query: 389 ADSYKCACPVTYTGKNCEVKQ 451 +SY C C ++GK CE +Q Sbjct: 1402 LNSYSCKCQPGFSGKRCETEQ 1422 Score = 54.0 bits (124), Expect = 3e-07 Identities = 26/93 (27%), Positives = 41/93 (44%), Gaps = 3/93 (3%) Frame = +2 Query: 212 QNCFTCAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLC-GPGKCMNT 388 +N C+ + CLN G+C + + GY C C GF G +C+ C+ C C + Sbjct: 1268 ENINECSSSPCLNKGICVDGVA--GYRCTCVKGFVGLHCETEVNECQSNPCLNNAVCEDQ 1325 Query: 389 ADSYKCACPVTYTGKNC--EVKQLIEYPAFTGS 481 + C CP + G C V + + P G+ Sbjct: 1326 VGGFLCKCPPGFLGTRCGKNVDECLSQPCKNGA 1358 Score = 38.7 bits (86), Expect = 0.013 Identities = 23/70 (32%), Positives = 31/70 (44%) Frame = +2 Query: 242 CLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLCGPGKCMNTADSYKCACPVT 421 CLN G C Y C C PG+ G+ C C+ GKC+ +C C + Sbjct: 3511 CLNGGRCVAP-----YQCDCPPGWTGSRCHTA--VCQSPCLNGGKCVRPN---RCHCLSS 3560 Query: 422 YTGKNCEVKQ 451 +TG NC K+ Sbjct: 3561 WTGHNCSRKR 3570 Score = 35.1 bits (77), Expect = 0.16 Identities = 22/79 (27%), Positives = 31/79 (39%) Frame = +2 Query: 242 CLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLCGPGKCMNTADSYKCACPVT 421 C N G+CQ C C G+ G C+ C G+C+ Y+C CP Sbjct: 3479 CQNGGICQRP-----NACSCPEGWMGRLCEE--PICILPCLNGGRCVAP---YQCDCPPG 3528 Query: 422 YTGKNCEVKQLIEYPAFTG 478 +TG C + + P G Sbjct: 3529 WTGSRCHT-AVCQSPCLNG 3546 Score = 29.5 bits (63), Expect = 7.8 Identities = 12/23 (52%), Positives = 15/23 (65%), Gaps = 2/23 (8%) Frame = +2 Query: 377 CMNTADSYKCACPVTYT--GKNC 439 C+N SY C+C +YT GKNC Sbjct: 1764 CLNVDGSYICSCVPSYTGDGKNC 1786 >AL592463-2|CAH73558.1| 3548|Homo sapiens sushi, von Willebrand factor type A, EGF and pentraxin domain containing 1 protein. Length = 3548 Score = 66.1 bits (154), Expect = 7e-11 Identities = 28/74 (37%), Positives = 42/74 (56%), Gaps = 1/74 (1%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLCGPG-KCMNTADSYK 403 C N CLNN VC++ + G++C C PGF G C + + C C G C + A+S++ Sbjct: 1288 CQSNPCLNNAVCEDQVG--GFLCKCPPGFLGTRCGKNVDECLSQPCKNGATCKDGANSFR 1345 Query: 404 CACPVTYTGKNCEV 445 C C +TG +CE+ Sbjct: 1346 CLCAAGFTGSHCEL 1359 Score = 61.7 bits (143), Expect = 2e-09 Identities = 29/73 (39%), Positives = 37/73 (50%), Gaps = 1/73 (1%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLC-GPGKCMNTADSYK 403 C N C N+G CQ+ GYVCLC G+ G C+ + C P C G C + + Sbjct: 1174 CFFNPCHNSGTCQQL--GRGYVCLCPLGYTGLKCETDIDECSPLPCLNNGVCKDLVGEFI 1231 Query: 404 CACPVTYTGKNCE 442 C CP YTG+ CE Sbjct: 1232 CECPSGYTGQRCE 1244 Score = 57.6 bits (133), Expect = 3e-08 Identities = 25/81 (30%), Positives = 40/81 (49%), Gaps = 1/81 (1%) Frame = +2 Query: 212 QNCFTCAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLC-GPGKCMNT 388 +N C C N C++ + + CLCA GF G++C+ C+ C C++ Sbjct: 1321 KNVDECLSQPCKNGATCKDGA--NSFRCLCAAGFTGSHCELNINECQSNPCRNQATCVDE 1378 Query: 389 ADSYKCACPVTYTGKNCEVKQ 451 +SY C C ++GK CE +Q Sbjct: 1379 LNSYSCKCQPGFSGKRCETEQ 1399 Score = 54.0 bits (124), Expect = 3e-07 Identities = 26/93 (27%), Positives = 41/93 (44%), Gaps = 3/93 (3%) Frame = +2 Query: 212 QNCFTCAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLC-GPGKCMNT 388 +N C+ + CLN G+C + + GY C C GF G +C+ C+ C C + Sbjct: 1245 ENINECSSSPCLNKGICVDGVA--GYRCTCVKGFVGLHCETEVNECQSNPCLNNAVCEDQ 1302 Query: 389 ADSYKCACPVTYTGKNC--EVKQLIEYPAFTGS 481 + C CP + G C V + + P G+ Sbjct: 1303 VGGFLCKCPPGFLGTRCGKNVDECLSQPCKNGA 1335 Score = 38.7 bits (86), Expect = 0.013 Identities = 23/70 (32%), Positives = 31/70 (44%) Frame = +2 Query: 242 CLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLCGPGKCMNTADSYKCACPVT 421 CLN G C Y C C PG+ G+ C C+ GKC+ +C C + Sbjct: 3485 CLNGGRCVAP-----YQCDCPPGWTGSRCHTA--VCQSPCLNGGKCVRPN---RCHCLSS 3534 Query: 422 YTGKNCEVKQ 451 +TG NC K+ Sbjct: 3535 WTGHNCSRKR 3544 Score = 35.1 bits (77), Expect = 0.16 Identities = 22/79 (27%), Positives = 31/79 (39%) Frame = +2 Query: 242 CLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLCGPGKCMNTADSYKCACPVT 421 C N G+CQ C C G+ G C+ C G+C+ Y+C CP Sbjct: 3453 CQNGGICQRP-----NACSCPEGWMGRLCEE--PICILPCLNGGRCVAP---YQCDCPPG 3502 Query: 422 YTGKNCEVKQLIEYPAFTG 478 +TG C + + P G Sbjct: 3503 WTGSRCHT-AVCQSPCLNG 3520 >AL589916-3|CAM13294.1| 594|Homo sapiens EGF-like-domain, multiple 11 protein. Length = 594 Score = 66.1 bits (154), Expect = 7e-11 Identities = 32/82 (39%), Positives = 42/82 (51%), Gaps = 4/82 (4%) Frame = +2 Query: 212 QNCFTCAPNLCLNNGVC---QEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLCGPGKCM 382 Q C+ C NNG C +E E Y C+C P F G NC I C+P +C G C Sbjct: 212 QELDACSFKPCKNNGSCINKRENWDEQAYECVCHPPFTGKNCSEIIGQCQPHVCFHGNCS 271 Query: 383 N-TADSYKCACPVTYTGKNCEV 445 N T++S+ C C ++G CEV Sbjct: 272 NITSNSFICECDEQFSGPFCEV 293 Score = 45.6 bits (103), Expect = 1e-04 Identities = 23/72 (31%), Positives = 32/72 (44%), Gaps = 6/72 (8%) Frame = +2 Query: 242 CLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLC-GPGKCMNTAD-----SYK 403 C +G C Y C C P F G C + ++C C G C+N + +Y+ Sbjct: 183 CSGHGKCLSEAWSKTYSCHCQPPFSGKYCQEL-DACSFKPCKNNGSCINKRENWDEQAYE 241 Query: 404 CACPVTYTGKNC 439 C C +TGKNC Sbjct: 242 CVCHPPFTGKNC 253 Score = 38.3 bits (85), Expect = 0.017 Identities = 21/73 (28%), Positives = 35/73 (47%), Gaps = 1/73 (1%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLCGP-GKCMNTADSYK 403 C P++C + G C +T + ++C C F G C+ + C L G C N++ +Y Sbjct: 260 CQPHVCFH-GNCSN-ITSNSFICECDEQFSGPFCEVSAKPCVSLLFWKRGICPNSSSAYT 317 Query: 404 CACPVTYTGKNCE 442 CP + +N E Sbjct: 318 YECPKGSSSQNGE 330 Score = 36.7 bits (81), Expect = 0.052 Identities = 18/52 (34%), Positives = 23/52 (44%), Gaps = 1/52 (1%) Frame = +2 Query: 290 VCLCAPGFGGNNCDRIGESCRP-GLCGPGKCMNTADSYKCACPVTYTGKNCE 442 +C+C+P F C I SC L C Y C+C +T KNCE Sbjct: 355 MCICSPIFTDLLCKSIQTSCESFPLRNNATCKKCEKDYPCSCISGFTEKNCE 406 Score = 31.1 bits (67), Expect = 2.6 Identities = 18/67 (26%), Positives = 25/67 (37%), Gaps = 3/67 (4%) Frame = +2 Query: 248 NNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCR---PGLCGPGKCMNTADSYKCACPV 418 NN C++ E Y C C GF NC++ + C+ C N +K C Sbjct: 381 NNATCKKC--EKDYPCSCISGFTEKNCEKAIDHCKLLSINCLNEEWCFNIIGRFKYVCIP 438 Query: 419 TYTGKNC 439 T C Sbjct: 439 GCTKNPC 445 >AL589916-2|CAI12363.2| 619|Homo sapiens EGF-like-domain, multiple 11 protein. Length = 619 Score = 66.1 bits (154), Expect = 7e-11 Identities = 32/82 (39%), Positives = 42/82 (51%), Gaps = 4/82 (4%) Frame = +2 Query: 212 QNCFTCAPNLCLNNGVC---QEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLCGPGKCM 382 Q C+ C NNG C +E E Y C+C P F G NC I C+P +C G C Sbjct: 212 QELDACSFKPCKNNGSCINKRENWDEQAYECVCHPPFTGKNCSEIIGQCQPHVCFHGNCS 271 Query: 383 N-TADSYKCACPVTYTGKNCEV 445 N T++S+ C C ++G CEV Sbjct: 272 NITSNSFICECDEQFSGPFCEV 293 Score = 45.6 bits (103), Expect = 1e-04 Identities = 23/72 (31%), Positives = 32/72 (44%), Gaps = 6/72 (8%) Frame = +2 Query: 242 CLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLC-GPGKCMNTAD-----SYK 403 C +G C Y C C P F G C + ++C C G C+N + +Y+ Sbjct: 183 CSGHGKCLSEAWSKTYSCHCQPPFSGKYCQEL-DACSFKPCKNNGSCINKRENWDEQAYE 241 Query: 404 CACPVTYTGKNC 439 C C +TGKNC Sbjct: 242 CVCHPPFTGKNC 253 Score = 38.3 bits (85), Expect = 0.017 Identities = 21/73 (28%), Positives = 35/73 (47%), Gaps = 1/73 (1%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLCGP-GKCMNTADSYK 403 C P++C + G C +T + ++C C F G C+ + C L G C N++ +Y Sbjct: 260 CQPHVCFH-GNCSN-ITSNSFICECDEQFSGPFCEVSAKPCVSLLFWKRGICPNSSSAYT 317 Query: 404 CACPVTYTGKNCE 442 CP + +N E Sbjct: 318 YECPKGSSSQNGE 330 Score = 36.7 bits (81), Expect = 0.052 Identities = 18/52 (34%), Positives = 23/52 (44%), Gaps = 1/52 (1%) Frame = +2 Query: 290 VCLCAPGFGGNNCDRIGESCRP-GLCGPGKCMNTADSYKCACPVTYTGKNCE 442 +C+C+P F C I SC L C Y C+C +T KNCE Sbjct: 355 MCICSPIFTDLLCKSIQTSCESFPLRNNATCKKCEKDYPCSCISGFTEKNCE 406 Score = 31.1 bits (67), Expect = 2.6 Identities = 18/67 (26%), Positives = 25/67 (37%), Gaps = 3/67 (4%) Frame = +2 Query: 248 NNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCR---PGLCGPGKCMNTADSYKCACPV 418 NN C++ E Y C C GF NC++ + C+ C N +K C Sbjct: 381 NNATCKKC--EKDYPCSCISGFTEKNCEKAIDHCKLLSINCLNEEWCFNIIGRFKYVCIP 438 Query: 419 TYTGKNC 439 T C Sbjct: 439 GCTKNPC 445 >AL365217-4|CAM23289.1| 594|Homo sapiens EGF-like-domain, multiple 11 protein. Length = 594 Score = 66.1 bits (154), Expect = 7e-11 Identities = 32/82 (39%), Positives = 42/82 (51%), Gaps = 4/82 (4%) Frame = +2 Query: 212 QNCFTCAPNLCLNNGVC---QEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLCGPGKCM 382 Q C+ C NNG C +E E Y C+C P F G NC I C+P +C G C Sbjct: 212 QELDACSFKPCKNNGSCINKRENWDEQAYECVCHPPFTGKNCSEIIGQCQPHVCFHGNCS 271 Query: 383 N-TADSYKCACPVTYTGKNCEV 445 N T++S+ C C ++G CEV Sbjct: 272 NITSNSFICECDEQFSGPFCEV 293 Score = 45.6 bits (103), Expect = 1e-04 Identities = 23/72 (31%), Positives = 32/72 (44%), Gaps = 6/72 (8%) Frame = +2 Query: 242 CLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLC-GPGKCMNTAD-----SYK 403 C +G C Y C C P F G C + ++C C G C+N + +Y+ Sbjct: 183 CSGHGKCLSEAWSKTYSCHCQPPFSGKYCQEL-DACSFKPCKNNGSCINKRENWDEQAYE 241 Query: 404 CACPVTYTGKNC 439 C C +TGKNC Sbjct: 242 CVCHPPFTGKNC 253 Score = 38.3 bits (85), Expect = 0.017 Identities = 21/73 (28%), Positives = 35/73 (47%), Gaps = 1/73 (1%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLCGP-GKCMNTADSYK 403 C P++C + G C +T + ++C C F G C+ + C L G C N++ +Y Sbjct: 260 CQPHVCFH-GNCSN-ITSNSFICECDEQFSGPFCEVSAKPCVSLLFWKRGICPNSSSAYT 317 Query: 404 CACPVTYTGKNCE 442 CP + +N E Sbjct: 318 YECPKGSSSQNGE 330 Score = 36.7 bits (81), Expect = 0.052 Identities = 18/52 (34%), Positives = 23/52 (44%), Gaps = 1/52 (1%) Frame = +2 Query: 290 VCLCAPGFGGNNCDRIGESCRP-GLCGPGKCMNTADSYKCACPVTYTGKNCE 442 +C+C+P F C I SC L C Y C+C +T KNCE Sbjct: 355 MCICSPIFTDLLCKSIQTSCESFPLRNNATCKKCEKDYPCSCISGFTEKNCE 406 Score = 31.1 bits (67), Expect = 2.6 Identities = 18/67 (26%), Positives = 25/67 (37%), Gaps = 3/67 (4%) Frame = +2 Query: 248 NNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCR---PGLCGPGKCMNTADSYKCACPV 418 NN C++ E Y C C GF NC++ + C+ C N +K C Sbjct: 381 NNATCKKC--EKDYPCSCISGFTEKNCEKAIDHCKLLSINCLNEEWCFNIIGRFKYVCIP 438 Query: 419 TYTGKNC 439 T C Sbjct: 439 GCTKNPC 445 >AL365217-3|CAI16606.1| 619|Homo sapiens EGF-like-domain, multiple 11 protein. Length = 619 Score = 66.1 bits (154), Expect = 7e-11 Identities = 32/82 (39%), Positives = 42/82 (51%), Gaps = 4/82 (4%) Frame = +2 Query: 212 QNCFTCAPNLCLNNGVC---QEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLCGPGKCM 382 Q C+ C NNG C +E E Y C+C P F G NC I C+P +C G C Sbjct: 212 QELDACSFKPCKNNGSCINKRENWDEQAYECVCHPPFTGKNCSEIIGQCQPHVCFHGNCS 271 Query: 383 N-TADSYKCACPVTYTGKNCEV 445 N T++S+ C C ++G CEV Sbjct: 272 NITSNSFICECDEQFSGPFCEV 293 Score = 45.6 bits (103), Expect = 1e-04 Identities = 23/72 (31%), Positives = 32/72 (44%), Gaps = 6/72 (8%) Frame = +2 Query: 242 CLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLC-GPGKCMNTAD-----SYK 403 C +G C Y C C P F G C + ++C C G C+N + +Y+ Sbjct: 183 CSGHGKCLSEAWSKTYSCHCQPPFSGKYCQEL-DACSFKPCKNNGSCINKRENWDEQAYE 241 Query: 404 CACPVTYTGKNC 439 C C +TGKNC Sbjct: 242 CVCHPPFTGKNC 253 Score = 38.3 bits (85), Expect = 0.017 Identities = 21/73 (28%), Positives = 35/73 (47%), Gaps = 1/73 (1%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLCGP-GKCMNTADSYK 403 C P++C + G C +T + ++C C F G C+ + C L G C N++ +Y Sbjct: 260 CQPHVCFH-GNCSN-ITSNSFICECDEQFSGPFCEVSAKPCVSLLFWKRGICPNSSSAYT 317 Query: 404 CACPVTYTGKNCE 442 CP + +N E Sbjct: 318 YECPKGSSSQNGE 330 Score = 36.7 bits (81), Expect = 0.052 Identities = 18/52 (34%), Positives = 23/52 (44%), Gaps = 1/52 (1%) Frame = +2 Query: 290 VCLCAPGFGGNNCDRIGESCRP-GLCGPGKCMNTADSYKCACPVTYTGKNCE 442 +C+C+P F C I SC L C Y C+C +T KNCE Sbjct: 355 MCICSPIFTDLLCKSIQTSCESFPLRNNATCKKCEKDYPCSCISGFTEKNCE 406 Score = 31.1 bits (67), Expect = 2.6 Identities = 18/67 (26%), Positives = 25/67 (37%), Gaps = 3/67 (4%) Frame = +2 Query: 248 NNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCR---PGLCGPGKCMNTADSYKCACPV 418 NN C++ E Y C C GF NC++ + C+ C N +K C Sbjct: 381 NNATCKKC--EKDYPCSCISGFTEKNCEKAIDHCKLLSINCLNEEWCFNIIGRFKYVCIP 438 Query: 419 TYTGKNC 439 T C Sbjct: 439 GCTKNPC 445 >AL354982-2|CAH74139.1| 3548|Homo sapiens sushi, von Willebrand factor type A, EGF and pentraxin domain containing 1 protein. Length = 3548 Score = 66.1 bits (154), Expect = 7e-11 Identities = 28/74 (37%), Positives = 42/74 (56%), Gaps = 1/74 (1%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLCGPG-KCMNTADSYK 403 C N CLNN VC++ + G++C C PGF G C + + C C G C + A+S++ Sbjct: 1288 CQSNPCLNNAVCEDQVG--GFLCKCPPGFLGTRCGKNVDECLSQPCKNGATCKDGANSFR 1345 Query: 404 CACPVTYTGKNCEV 445 C C +TG +CE+ Sbjct: 1346 CLCAAGFTGSHCEL 1359 Score = 61.7 bits (143), Expect = 2e-09 Identities = 29/73 (39%), Positives = 37/73 (50%), Gaps = 1/73 (1%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLC-GPGKCMNTADSYK 403 C N C N+G CQ+ GYVCLC G+ G C+ + C P C G C + + Sbjct: 1174 CFFNPCHNSGTCQQL--GRGYVCLCPLGYTGLKCETDIDECSPLPCLNNGVCKDLVGEFI 1231 Query: 404 CACPVTYTGKNCE 442 C CP YTG+ CE Sbjct: 1232 CECPSGYTGQRCE 1244 Score = 57.6 bits (133), Expect = 3e-08 Identities = 25/81 (30%), Positives = 40/81 (49%), Gaps = 1/81 (1%) Frame = +2 Query: 212 QNCFTCAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLC-GPGKCMNT 388 +N C C N C++ + + CLCA GF G++C+ C+ C C++ Sbjct: 1321 KNVDECLSQPCKNGATCKDGA--NSFRCLCAAGFTGSHCELNINECQSNPCRNQATCVDE 1378 Query: 389 ADSYKCACPVTYTGKNCEVKQ 451 +SY C C ++GK CE +Q Sbjct: 1379 LNSYSCKCQPGFSGKRCETEQ 1399 Score = 54.0 bits (124), Expect = 3e-07 Identities = 26/93 (27%), Positives = 41/93 (44%), Gaps = 3/93 (3%) Frame = +2 Query: 212 QNCFTCAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLC-GPGKCMNT 388 +N C+ + CLN G+C + + GY C C GF G +C+ C+ C C + Sbjct: 1245 ENINECSSSPCLNKGICVDGVA--GYRCTCVKGFVGLHCETEVNECQSNPCLNNAVCEDQ 1302 Query: 389 ADSYKCACPVTYTGKNC--EVKQLIEYPAFTGS 481 + C CP + G C V + + P G+ Sbjct: 1303 VGGFLCKCPPGFLGTRCGKNVDECLSQPCKNGA 1335 Score = 38.7 bits (86), Expect = 0.013 Identities = 23/70 (32%), Positives = 31/70 (44%) Frame = +2 Query: 242 CLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLCGPGKCMNTADSYKCACPVT 421 CLN G C Y C C PG+ G+ C C+ GKC+ +C C + Sbjct: 3485 CLNGGRCVAP-----YQCDCPPGWTGSRCHTA--VCQSPCLNGGKCVRPN---RCHCLSS 3534 Query: 422 YTGKNCEVKQ 451 +TG NC K+ Sbjct: 3535 WTGHNCSRKR 3544 Score = 35.1 bits (77), Expect = 0.16 Identities = 22/79 (27%), Positives = 31/79 (39%) Frame = +2 Query: 242 CLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLCGPGKCMNTADSYKCACPVT 421 C N G+CQ C C G+ G C+ C G+C+ Y+C CP Sbjct: 3453 CQNGGICQRP-----NACSCPEGWMGRLCEE--PICILPCLNGGRCVAP---YQCDCPPG 3502 Query: 422 YTGKNCEVKQLIEYPAFTG 478 +TG C + + P G Sbjct: 3503 WTGSRCHT-AVCQSPCLNG 3520 >AL158158-3|CAI14068.1| 3548|Homo sapiens sushi, von Willebrand factor type A, EGF and pentraxin domain containing 1 protein. Length = 3548 Score = 66.1 bits (154), Expect = 7e-11 Identities = 28/74 (37%), Positives = 42/74 (56%), Gaps = 1/74 (1%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLCGPG-KCMNTADSYK 403 C N CLNN VC++ + G++C C PGF G C + + C C G C + A+S++ Sbjct: 1288 CQSNPCLNNAVCEDQVG--GFLCKCPPGFLGTRCGKNVDECLSQPCKNGATCKDGANSFR 1345 Query: 404 CACPVTYTGKNCEV 445 C C +TG +CE+ Sbjct: 1346 CLCAAGFTGSHCEL 1359 Score = 61.7 bits (143), Expect = 2e-09 Identities = 29/73 (39%), Positives = 37/73 (50%), Gaps = 1/73 (1%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLC-GPGKCMNTADSYK 403 C N C N+G CQ+ GYVCLC G+ G C+ + C P C G C + + Sbjct: 1174 CFFNPCHNSGTCQQL--GRGYVCLCPLGYTGLKCETDIDECSPLPCLNNGVCKDLVGEFI 1231 Query: 404 CACPVTYTGKNCE 442 C CP YTG+ CE Sbjct: 1232 CECPSGYTGQRCE 1244 Score = 57.6 bits (133), Expect = 3e-08 Identities = 25/81 (30%), Positives = 40/81 (49%), Gaps = 1/81 (1%) Frame = +2 Query: 212 QNCFTCAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLC-GPGKCMNT 388 +N C C N C++ + + CLCA GF G++C+ C+ C C++ Sbjct: 1321 KNVDECLSQPCKNGATCKDGA--NSFRCLCAAGFTGSHCELNINECQSNPCRNQATCVDE 1378 Query: 389 ADSYKCACPVTYTGKNCEVKQ 451 +SY C C ++GK CE +Q Sbjct: 1379 LNSYSCKCQPGFSGKRCETEQ 1399 Score = 54.0 bits (124), Expect = 3e-07 Identities = 26/93 (27%), Positives = 41/93 (44%), Gaps = 3/93 (3%) Frame = +2 Query: 212 QNCFTCAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLC-GPGKCMNT 388 +N C+ + CLN G+C + + GY C C GF G +C+ C+ C C + Sbjct: 1245 ENINECSSSPCLNKGICVDGVA--GYRCTCVKGFVGLHCETEVNECQSNPCLNNAVCEDQ 1302 Query: 389 ADSYKCACPVTYTGKNC--EVKQLIEYPAFTGS 481 + C CP + G C V + + P G+ Sbjct: 1303 VGGFLCKCPPGFLGTRCGKNVDECLSQPCKNGA 1335 Score = 38.7 bits (86), Expect = 0.013 Identities = 23/70 (32%), Positives = 31/70 (44%) Frame = +2 Query: 242 CLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLCGPGKCMNTADSYKCACPVT 421 CLN G C Y C C PG+ G+ C C+ GKC+ +C C + Sbjct: 3485 CLNGGRCVAP-----YQCDCPPGWTGSRCHTA--VCQSPCLNGGKCVRPN---RCHCLSS 3534 Query: 422 YTGKNCEVKQ 451 +TG NC K+ Sbjct: 3535 WTGHNCSRKR 3544 Score = 35.1 bits (77), Expect = 0.16 Identities = 22/79 (27%), Positives = 31/79 (39%) Frame = +2 Query: 242 CLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLCGPGKCMNTADSYKCACPVT 421 C N G+CQ C C G+ G C+ C G+C+ Y+C CP Sbjct: 3453 CQNGGICQRP-----NACSCPEGWMGRLCEE--PICILPCLNGGRCVAP---YQCDCPPG 3502 Query: 422 YTGKNCEVKQLIEYPAFTG 478 +TG C + + P G Sbjct: 3503 WTGSRCHT-AVCQSPCLNG 3520 >AL132767-2|CAM28320.1| 594|Homo sapiens EGF-like-domain, multiple 11 protein. Length = 594 Score = 66.1 bits (154), Expect = 7e-11 Identities = 32/82 (39%), Positives = 42/82 (51%), Gaps = 4/82 (4%) Frame = +2 Query: 212 QNCFTCAPNLCLNNGVC---QEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLCGPGKCM 382 Q C+ C NNG C +E E Y C+C P F G NC I C+P +C G C Sbjct: 212 QELDACSFKPCKNNGSCINKRENWDEQAYECVCHPPFTGKNCSEIIGQCQPHVCFHGNCS 271 Query: 383 N-TADSYKCACPVTYTGKNCEV 445 N T++S+ C C ++G CEV Sbjct: 272 NITSNSFICECDEQFSGPFCEV 293 Score = 45.6 bits (103), Expect = 1e-04 Identities = 23/72 (31%), Positives = 32/72 (44%), Gaps = 6/72 (8%) Frame = +2 Query: 242 CLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLC-GPGKCMNTAD-----SYK 403 C +G C Y C C P F G C + ++C C G C+N + +Y+ Sbjct: 183 CSGHGKCLSEAWSKTYSCHCQPPFSGKYCQEL-DACSFKPCKNNGSCINKRENWDEQAYE 241 Query: 404 CACPVTYTGKNC 439 C C +TGKNC Sbjct: 242 CVCHPPFTGKNC 253 Score = 38.3 bits (85), Expect = 0.017 Identities = 21/73 (28%), Positives = 35/73 (47%), Gaps = 1/73 (1%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLCGP-GKCMNTADSYK 403 C P++C + G C +T + ++C C F G C+ + C L G C N++ +Y Sbjct: 260 CQPHVCFH-GNCSN-ITSNSFICECDEQFSGPFCEVSAKPCVSLLFWKRGICPNSSSAYT 317 Query: 404 CACPVTYTGKNCE 442 CP + +N E Sbjct: 318 YECPKGSSSQNGE 330 Score = 36.7 bits (81), Expect = 0.052 Identities = 18/52 (34%), Positives = 23/52 (44%), Gaps = 1/52 (1%) Frame = +2 Query: 290 VCLCAPGFGGNNCDRIGESCRP-GLCGPGKCMNTADSYKCACPVTYTGKNCE 442 +C+C+P F C I SC L C Y C+C +T KNCE Sbjct: 355 MCICSPIFTDLLCKSIQTSCESFPLRNNATCKKCEKDYPCSCISGFTEKNCE 406 Score = 31.1 bits (67), Expect = 2.6 Identities = 18/67 (26%), Positives = 25/67 (37%), Gaps = 3/67 (4%) Frame = +2 Query: 248 NNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCR---PGLCGPGKCMNTADSYKCACPV 418 NN C++ E Y C C GF NC++ + C+ C N +K C Sbjct: 381 NNATCKKC--EKDYPCSCISGFTEKNCEKAIDHCKLLSINCLNEEWCFNIIGRFKYVCIP 438 Query: 419 TYTGKNC 439 T C Sbjct: 439 GCTKNPC 445 >AL132767-1|CAI22904.1| 619|Homo sapiens EGF-like-domain, multiple 11 protein. Length = 619 Score = 66.1 bits (154), Expect = 7e-11 Identities = 32/82 (39%), Positives = 42/82 (51%), Gaps = 4/82 (4%) Frame = +2 Query: 212 QNCFTCAPNLCLNNGVC---QEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLCGPGKCM 382 Q C+ C NNG C +E E Y C+C P F G NC I C+P +C G C Sbjct: 212 QELDACSFKPCKNNGSCINKRENWDEQAYECVCHPPFTGKNCSEIIGQCQPHVCFHGNCS 271 Query: 383 N-TADSYKCACPVTYTGKNCEV 445 N T++S+ C C ++G CEV Sbjct: 272 NITSNSFICECDEQFSGPFCEV 293 Score = 45.6 bits (103), Expect = 1e-04 Identities = 23/72 (31%), Positives = 32/72 (44%), Gaps = 6/72 (8%) Frame = +2 Query: 242 CLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLC-GPGKCMNTAD-----SYK 403 C +G C Y C C P F G C + ++C C G C+N + +Y+ Sbjct: 183 CSGHGKCLSEAWSKTYSCHCQPPFSGKYCQEL-DACSFKPCKNNGSCINKRENWDEQAYE 241 Query: 404 CACPVTYTGKNC 439 C C +TGKNC Sbjct: 242 CVCHPPFTGKNC 253 Score = 38.3 bits (85), Expect = 0.017 Identities = 21/73 (28%), Positives = 35/73 (47%), Gaps = 1/73 (1%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLCGP-GKCMNTADSYK 403 C P++C + G C +T + ++C C F G C+ + C L G C N++ +Y Sbjct: 260 CQPHVCFH-GNCSN-ITSNSFICECDEQFSGPFCEVSAKPCVSLLFWKRGICPNSSSAYT 317 Query: 404 CACPVTYTGKNCE 442 CP + +N E Sbjct: 318 YECPKGSSSQNGE 330 Score = 36.7 bits (81), Expect = 0.052 Identities = 18/52 (34%), Positives = 23/52 (44%), Gaps = 1/52 (1%) Frame = +2 Query: 290 VCLCAPGFGGNNCDRIGESCRP-GLCGPGKCMNTADSYKCACPVTYTGKNCE 442 +C+C+P F C I SC L C Y C+C +T KNCE Sbjct: 355 MCICSPIFTDLLCKSIQTSCESFPLRNNATCKKCEKDYPCSCISGFTEKNCE 406 Score = 31.1 bits (67), Expect = 2.6 Identities = 18/67 (26%), Positives = 25/67 (37%), Gaps = 3/67 (4%) Frame = +2 Query: 248 NNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCR---PGLCGPGKCMNTADSYKCACPV 418 NN C++ E Y C C GF NC++ + C+ C N +K C Sbjct: 381 NNATCKKC--EKDYPCSCISGFTEKNCEKAIDHCKLLSINCLNEEWCFNIIGRFKYVCIP 438 Query: 419 TYTGKNC 439 T C Sbjct: 439 GCTKNPC 445 >AL109612-2|CAM27006.1| 594|Homo sapiens EGF-like-domain, multiple 11 protein. Length = 594 Score = 66.1 bits (154), Expect = 7e-11 Identities = 32/82 (39%), Positives = 42/82 (51%), Gaps = 4/82 (4%) Frame = +2 Query: 212 QNCFTCAPNLCLNNGVC---QEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLCGPGKCM 382 Q C+ C NNG C +E E Y C+C P F G NC I C+P +C G C Sbjct: 212 QELDACSFKPCKNNGSCINKRENWDEQAYECVCHPPFTGKNCSEIIGQCQPHVCFHGNCS 271 Query: 383 N-TADSYKCACPVTYTGKNCEV 445 N T++S+ C C ++G CEV Sbjct: 272 NITSNSFICECDEQFSGPFCEV 293 Score = 45.6 bits (103), Expect = 1e-04 Identities = 23/72 (31%), Positives = 32/72 (44%), Gaps = 6/72 (8%) Frame = +2 Query: 242 CLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLC-GPGKCMNTAD-----SYK 403 C +G C Y C C P F G C + ++C C G C+N + +Y+ Sbjct: 183 CSGHGKCLSEAWSKTYSCHCQPPFSGKYCQEL-DACSFKPCKNNGSCINKRENWDEQAYE 241 Query: 404 CACPVTYTGKNC 439 C C +TGKNC Sbjct: 242 CVCHPPFTGKNC 253 Score = 38.3 bits (85), Expect = 0.017 Identities = 21/73 (28%), Positives = 35/73 (47%), Gaps = 1/73 (1%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLCGP-GKCMNTADSYK 403 C P++C + G C +T + ++C C F G C+ + C L G C N++ +Y Sbjct: 260 CQPHVCFH-GNCSN-ITSNSFICECDEQFSGPFCEVSAKPCVSLLFWKRGICPNSSSAYT 317 Query: 404 CACPVTYTGKNCE 442 CP + +N E Sbjct: 318 YECPKGSSSQNGE 330 Score = 36.7 bits (81), Expect = 0.052 Identities = 18/52 (34%), Positives = 23/52 (44%), Gaps = 1/52 (1%) Frame = +2 Query: 290 VCLCAPGFGGNNCDRIGESCRP-GLCGPGKCMNTADSYKCACPVTYTGKNCE 442 +C+C+P F C I SC L C Y C+C +T KNCE Sbjct: 355 MCICSPIFTDLLCKSIQTSCESFPLRNNATCKKCEKDYPCSCISGFTEKNCE 406 Score = 31.1 bits (67), Expect = 2.6 Identities = 18/67 (26%), Positives = 25/67 (37%), Gaps = 3/67 (4%) Frame = +2 Query: 248 NNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCR---PGLCGPGKCMNTADSYKCACPV 418 NN C++ E Y C C GF NC++ + C+ C N +K C Sbjct: 381 NNATCKKC--EKDYPCSCISGFTEKNCEKAIDHCKLLSINCLNEEWCFNIIGRFKYVCIP 438 Query: 419 TYTGKNC 439 T C Sbjct: 439 GCTKNPC 445 >AL109612-1|CAI18881.1| 619|Homo sapiens EGF-like-domain, multiple 11 protein. Length = 619 Score = 66.1 bits (154), Expect = 7e-11 Identities = 32/82 (39%), Positives = 42/82 (51%), Gaps = 4/82 (4%) Frame = +2 Query: 212 QNCFTCAPNLCLNNGVC---QEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLCGPGKCM 382 Q C+ C NNG C +E E Y C+C P F G NC I C+P +C G C Sbjct: 212 QELDACSFKPCKNNGSCINKRENWDEQAYECVCHPPFTGKNCSEIIGQCQPHVCFHGNCS 271 Query: 383 N-TADSYKCACPVTYTGKNCEV 445 N T++S+ C C ++G CEV Sbjct: 272 NITSNSFICECDEQFSGPFCEV 293 Score = 45.6 bits (103), Expect = 1e-04 Identities = 23/72 (31%), Positives = 32/72 (44%), Gaps = 6/72 (8%) Frame = +2 Query: 242 CLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLC-GPGKCMNTAD-----SYK 403 C +G C Y C C P F G C + ++C C G C+N + +Y+ Sbjct: 183 CSGHGKCLSEAWSKTYSCHCQPPFSGKYCQEL-DACSFKPCKNNGSCINKRENWDEQAYE 241 Query: 404 CACPVTYTGKNC 439 C C +TGKNC Sbjct: 242 CVCHPPFTGKNC 253 Score = 38.3 bits (85), Expect = 0.017 Identities = 21/73 (28%), Positives = 35/73 (47%), Gaps = 1/73 (1%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLCGP-GKCMNTADSYK 403 C P++C + G C +T + ++C C F G C+ + C L G C N++ +Y Sbjct: 260 CQPHVCFH-GNCSN-ITSNSFICECDEQFSGPFCEVSAKPCVSLLFWKRGICPNSSSAYT 317 Query: 404 CACPVTYTGKNCE 442 CP + +N E Sbjct: 318 YECPKGSSSQNGE 330 Score = 36.7 bits (81), Expect = 0.052 Identities = 18/52 (34%), Positives = 23/52 (44%), Gaps = 1/52 (1%) Frame = +2 Query: 290 VCLCAPGFGGNNCDRIGESCRP-GLCGPGKCMNTADSYKCACPVTYTGKNCE 442 +C+C+P F C I SC L C Y C+C +T KNCE Sbjct: 355 MCICSPIFTDLLCKSIQTSCESFPLRNNATCKKCEKDYPCSCISGFTEKNCE 406 Score = 31.1 bits (67), Expect = 2.6 Identities = 18/67 (26%), Positives = 25/67 (37%), Gaps = 3/67 (4%) Frame = +2 Query: 248 NNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCR---PGLCGPGKCMNTADSYKCACPV 418 NN C++ E Y C C GF NC++ + C+ C N +K C Sbjct: 381 NNATCKKC--EKDYPCSCISGFTEKNCEKAIDHCKLLSINCLNEEWCFNIIGRFKYVCIP 438 Query: 419 TYTGKNC 439 T C Sbjct: 439 GCTKNPC 445 >AK027870-1|BAB55420.1| 1316|Homo sapiens protein ( Homo sapiens cDNA FLJ14964 fis, clone PLACE4000581, moderately similar to FIBROPELLIN I PRECURSOR. ). Length = 1316 Score = 66.1 bits (154), Expect = 7e-11 Identities = 28/74 (37%), Positives = 42/74 (56%), Gaps = 1/74 (1%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLCGPG-KCMNTADSYK 403 C N CLNN VC++ + G++C C PGF G C + + C C G C + A+S++ Sbjct: 1078 CQSNPCLNNAVCEDQVG--GFLCKCPPGFLGTRCGKNVDECLSQPCKNGATCKDGANSFR 1135 Query: 404 CACPVTYTGKNCEV 445 C C +TG +CE+ Sbjct: 1136 CLCAAGFTGSHCEL 1149 Score = 61.7 bits (143), Expect = 2e-09 Identities = 29/73 (39%), Positives = 37/73 (50%), Gaps = 1/73 (1%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLC-GPGKCMNTADSYK 403 C N C N+G CQ+ GYVCLC G+ G C+ + C P C G C + + Sbjct: 964 CFFNPCHNSGTCQQL--GRGYVCLCPLGYTGLKCETDIDECSPLPCLNNGVCKDLVGEFI 1021 Query: 404 CACPVTYTGKNCE 442 C CP YTG+ CE Sbjct: 1022 CECPSGYTGQRCE 1034 Score = 57.6 bits (133), Expect = 3e-08 Identities = 25/81 (30%), Positives = 40/81 (49%), Gaps = 1/81 (1%) Frame = +2 Query: 212 QNCFTCAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLC-GPGKCMNT 388 +N C C N C++ + + CLCA GF G++C+ C+ C C++ Sbjct: 1111 KNVDECLSQPCKNGATCKDGA--NSFRCLCAAGFTGSHCELNINECQSNPCRNQATCVDE 1168 Query: 389 ADSYKCACPVTYTGKNCEVKQ 451 +SY C C ++GK CE +Q Sbjct: 1169 LNSYSCKCQPGFSGKRCETEQ 1189 Score = 54.0 bits (124), Expect = 3e-07 Identities = 26/93 (27%), Positives = 41/93 (44%), Gaps = 3/93 (3%) Frame = +2 Query: 212 QNCFTCAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLC-GPGKCMNT 388 +N C+ + CLN G+C + + GY C C GF G +C+ C+ C C + Sbjct: 1035 ENINECSSSPCLNKGICVDGVA--GYRCTCVKGFVGLHCETEVNECQSNPCLNNAVCEDQ 1092 Query: 389 ADSYKCACPVTYTGKNC--EVKQLIEYPAFTGS 481 + C CP + G C V + + P G+ Sbjct: 1093 VGGFLCKCPPGFLGTRCGKNVDECLSQPCKNGA 1125 >AJ619977-1|CAF04067.1| 3574|Homo sapiens SEL-OB protein protein. Length = 3574 Score = 66.1 bits (154), Expect = 7e-11 Identities = 28/74 (37%), Positives = 42/74 (56%), Gaps = 1/74 (1%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLCGPG-KCMNTADSYK 403 C N CLNN VC++ + G++C C PGF G C + + C C G C + A+S++ Sbjct: 1311 CQSNPCLNNAVCEDQVG--GFLCKCPPGFLGTRCGKNVDECLSQPCKNGATCKDGANSFR 1368 Query: 404 CACPVTYTGKNCEV 445 C C +TG +CE+ Sbjct: 1369 CLCAAGFTGSHCEL 1382 Score = 61.7 bits (143), Expect = 2e-09 Identities = 29/73 (39%), Positives = 37/73 (50%), Gaps = 1/73 (1%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLC-GPGKCMNTADSYK 403 C N C N+G CQ+ GYVCLC G+ G C+ + C P C G C + + Sbjct: 1197 CFFNPCHNSGTCQQL--GRGYVCLCPLGYTGLKCETDIDECSPLPCLNNGVCKDLVGEFI 1254 Query: 404 CACPVTYTGKNCE 442 C CP YTG+ CE Sbjct: 1255 CECPSGYTGQRCE 1267 Score = 57.6 bits (133), Expect = 3e-08 Identities = 25/81 (30%), Positives = 40/81 (49%), Gaps = 1/81 (1%) Frame = +2 Query: 212 QNCFTCAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLC-GPGKCMNT 388 +N C C N C++ + + CLCA GF G++C+ C+ C C++ Sbjct: 1344 KNVDECLSQPCKNGATCKDGA--NSFRCLCAAGFTGSHCELNINECQSNPCRNQATCVDE 1401 Query: 389 ADSYKCACPVTYTGKNCEVKQ 451 +SY C C ++GK CE +Q Sbjct: 1402 LNSYSCKCQPGFSGKRCETEQ 1422 Score = 54.0 bits (124), Expect = 3e-07 Identities = 26/93 (27%), Positives = 41/93 (44%), Gaps = 3/93 (3%) Frame = +2 Query: 212 QNCFTCAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLC-GPGKCMNT 388 +N C+ + CLN G+C + + GY C C GF G +C+ C+ C C + Sbjct: 1268 ENINECSSSPCLNKGICVDGVA--GYRCTCVKGFVGLHCETEVNECQSNPCLNNAVCEDQ 1325 Query: 389 ADSYKCACPVTYTGKNC--EVKQLIEYPAFTGS 481 + C CP + G C V + + P G+ Sbjct: 1326 VGGFLCKCPPGFLGTRCGKNVDECLSQPCKNGA 1358 Score = 38.7 bits (86), Expect = 0.013 Identities = 23/70 (32%), Positives = 31/70 (44%) Frame = +2 Query: 242 CLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLCGPGKCMNTADSYKCACPVT 421 CLN G C Y C C PG+ G+ C C+ GKC+ +C C + Sbjct: 3511 CLNGGRCVAP-----YQCDCPPGWTGSRCHTA--VCQSPCLNGGKCVRPN---RCHCLSS 3560 Query: 422 YTGKNCEVKQ 451 +TG NC K+ Sbjct: 3561 WTGHNCSRKR 3570 Score = 35.1 bits (77), Expect = 0.16 Identities = 22/79 (27%), Positives = 31/79 (39%) Frame = +2 Query: 242 CLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLCGPGKCMNTADSYKCACPVT 421 C N G+CQ C C G+ G C+ C G+C+ Y+C CP Sbjct: 3479 CQNGGICQRP-----NACSCPEGWMGRLCEE--PICILPCLNGGRCVAP---YQCDCPPG 3528 Query: 422 YTGKNCEVKQLIEYPAFTG 478 +TG C + + P G Sbjct: 3529 WTGSRCHT-AVCQSPCLNG 3546 Score = 29.5 bits (63), Expect = 7.8 Identities = 12/23 (52%), Positives = 15/23 (65%), Gaps = 2/23 (8%) Frame = +2 Query: 377 CMNTADSYKCACPVTYT--GKNC 439 C+N SY C+C +YT GKNC Sbjct: 1764 CLNVDGSYICSCVPSYTGDGKNC 1786 >AF279305-1|AAF81912.1| 653|Homo sapiens delta 4 protein. Length = 653 Score = 66.1 bits (154), Expect = 7e-11 Identities = 32/77 (41%), Positives = 39/77 (50%), Gaps = 3/77 (3%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLC-GPGKC--MNTADS 397 C N C N G C++ E GY CLC PG+ G +C+ SC C G C N + Sbjct: 296 CDSNPCRNGGSCKDQ--EDGYHCLCPPGYYGLHCEHSTLSCADSPCFNGGSCRERNQGAN 353 Query: 398 YKCACPVTYTGKNCEVK 448 Y C CP +TG NCE K Sbjct: 354 YACECPPNFTGSNCEKK 370 Score = 64.1 bits (149), Expect = 3e-10 Identities = 27/75 (36%), Positives = 38/75 (50%), Gaps = 1/75 (1%) Frame = +2 Query: 224 TCAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLC-GPGKCMNTADSY 400 +CA + C N G C+E Y C C P F G+NC++ + C C G+C+N S Sbjct: 333 SCADSPCFNGGSCRERNQGANYACECPPNFTGSNCEKKVDRCTSNPCANGGQCLNRGPSR 392 Query: 401 KCACPVTYTGKNCEV 445 C C +TG CE+ Sbjct: 393 MCRCRPGFTGTYCEL 407 Score = 56.0 bits (129), Expect = 8e-08 Identities = 27/84 (32%), Positives = 36/84 (42%), Gaps = 3/84 (3%) Frame = +2 Query: 242 CLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLC-GPGKCMNTADSYKCACPV 418 C N C + + Y C C PG+ G +C+ C C G C + D Y C CP Sbjct: 262 CKNGATCSNS-GQRSYTCTCRPGYTGVDCELELSECDSNPCRNGGSCKDQEDGYHCLCPP 320 Query: 419 TYTGKNCEVKQL--IEYPAFTGSA 484 Y G +CE L + P F G + Sbjct: 321 GYYGLHCEHSTLSCADSPCFNGGS 344 Score = 54.0 bits (124), Expect = 3e-07 Identities = 25/79 (31%), Positives = 34/79 (43%), Gaps = 1/79 (1%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLCGPG-KCMNTADSYK 403 C N C N G C +C C PGF G C+ C C G C + + Sbjct: 374 CTSNPCANGGQCLNRGPSR--MCRCRPGFTGTYCELHVSDCARNPCAHGGTCHDLENGLM 431 Query: 404 CACPVTYTGKNCEVKQLIE 460 C CP ++G+ CEV+ I+ Sbjct: 432 CTCPAGFSGRRCEVRTSID 450 Score = 49.6 bits (113), Expect = 7e-06 Identities = 25/77 (32%), Positives = 36/77 (46%), Gaps = 5/77 (6%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCD-RIG-ESCRPGLC-GPGKCMN--TA 391 CA N C + G C + E+G +C C GF G C+ R ++C C C + Sbjct: 412 CARNPCAHGGTCHDL--ENGLMCTCPAGFSGRRCEVRTSIDACASSPCFNRATCYTDLST 469 Query: 392 DSYKCACPVTYTGKNCE 442 D++ C CP + G CE Sbjct: 470 DTFVCNCPYGFVGSRCE 486 Score = 44.0 bits (99), Expect = 3e-04 Identities = 24/74 (32%), Positives = 34/74 (45%), Gaps = 3/74 (4%) Frame = +2 Query: 236 NLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESC-RPGLCGPG-KCMNTAD-SYKC 406 N C+ + C+ + C C G+GG CD+ C C G C N+ SY C Sbjct: 219 NECIPHNGCRHGTCSTPWQCTCDEGWGGLFCDQDLNYCTHHSPCKNGATCSNSGQRSYTC 278 Query: 407 ACPVTYTGKNCEVK 448 C YTG +CE++ Sbjct: 279 TCRPGYTGVDCELE 292 Score = 31.1 bits (67), Expect = 2.6 Identities = 17/54 (31%), Positives = 22/54 (40%), Gaps = 3/54 (5%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRI--GESCRPGLCG-PGKC 379 C +CL+ Q CLC PG+ G C+ CR G C P +C Sbjct: 185 CQQPICLSGCHEQNGYCSKPAECLCRPGWQGRLCNECIPHNGCRHGTCSTPWQC 238 >AF253468-1|AAF76427.1| 685|Homo sapiens notch ligand DLL4 protein. Length = 685 Score = 66.1 bits (154), Expect = 7e-11 Identities = 32/77 (41%), Positives = 39/77 (50%), Gaps = 3/77 (3%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLC-GPGKC--MNTADS 397 C N C N G C++ E GY CLC PG+ G +C+ SC C G C N + Sbjct: 328 CDSNPCRNGGSCKDQ--EDGYHCLCPPGYYGLHCEHSTLSCADSPCFNGGSCRERNQGAN 385 Query: 398 YKCACPVTYTGKNCEVK 448 Y C CP +TG NCE K Sbjct: 386 YACECPPNFTGSNCEKK 402 Score = 64.1 bits (149), Expect = 3e-10 Identities = 27/75 (36%), Positives = 38/75 (50%), Gaps = 1/75 (1%) Frame = +2 Query: 224 TCAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLC-GPGKCMNTADSY 400 +CA + C N G C+E Y C C P F G+NC++ + C C G+C+N S Sbjct: 365 SCADSPCFNGGSCRERNQGANYACECPPNFTGSNCEKKVDRCTSNPCANGGQCLNRGPSR 424 Query: 401 KCACPVTYTGKNCEV 445 C C +TG CE+ Sbjct: 425 MCRCRPGFTGTYCEL 439 Score = 56.0 bits (129), Expect = 8e-08 Identities = 27/84 (32%), Positives = 36/84 (42%), Gaps = 3/84 (3%) Frame = +2 Query: 242 CLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLC-GPGKCMNTADSYKCACPV 418 C N C + + Y C C PG+ G +C+ C C G C + D Y C CP Sbjct: 294 CKNGATCSNS-GQRSYTCTCRPGYTGVDCELELSECDSNPCRNGGSCKDQEDGYHCLCPP 352 Query: 419 TYTGKNCEVKQL--IEYPAFTGSA 484 Y G +CE L + P F G + Sbjct: 353 GYYGLHCEHSTLSCADSPCFNGGS 376 Score = 54.0 bits (124), Expect = 3e-07 Identities = 25/79 (31%), Positives = 34/79 (43%), Gaps = 1/79 (1%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLCGPG-KCMNTADSYK 403 C N C N G C +C C PGF G C+ C C G C + + Sbjct: 406 CTSNPCANGGQCLNRGPSR--MCRCRPGFTGTYCELHVSDCARNPCAHGGTCHDLENGLM 463 Query: 404 CACPVTYTGKNCEVKQLIE 460 C CP ++G+ CEV+ I+ Sbjct: 464 CTCPAGFSGRRCEVRTSID 482 Score = 49.6 bits (113), Expect = 7e-06 Identities = 25/77 (32%), Positives = 36/77 (46%), Gaps = 5/77 (6%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCD-RIG-ESCRPGLC-GPGKCMN--TA 391 CA N C + G C + E+G +C C GF G C+ R ++C C C + Sbjct: 444 CARNPCAHGGTCHDL--ENGLMCTCPAGFSGRRCEVRTSIDACASSPCFNRATCYTDLST 501 Query: 392 DSYKCACPVTYTGKNCE 442 D++ C CP + G CE Sbjct: 502 DTFVCNCPYGFVGSRCE 518 Score = 44.0 bits (99), Expect = 3e-04 Identities = 24/74 (32%), Positives = 34/74 (45%), Gaps = 3/74 (4%) Frame = +2 Query: 236 NLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESC-RPGLCGPG-KCMNTAD-SYKC 406 N C+ + C+ + C C G+GG CD+ C C G C N+ SY C Sbjct: 251 NECIPHNGCRHGTCSTPWQCTCDEGWGGLFCDQDLNYCTHHSPCKNGATCSNSGQRSYTC 310 Query: 407 ACPVTYTGKNCEVK 448 C YTG +CE++ Sbjct: 311 TCRPGYTGVDCELE 324 Score = 31.1 bits (67), Expect = 2.6 Identities = 17/54 (31%), Positives = 22/54 (40%), Gaps = 3/54 (5%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRI--GESCRPGLCG-PGKC 379 C +CL+ Q CLC PG+ G C+ CR G C P +C Sbjct: 217 CQQPICLSGCHEQNGYCSKPAECLCRPGWQGRLCNECIPHNGCRHGTCSTPWQC 270 >AB043894-1|BAB18581.1| 685|Homo sapiens Delta-4 protein. Length = 685 Score = 66.1 bits (154), Expect = 7e-11 Identities = 32/77 (41%), Positives = 39/77 (50%), Gaps = 3/77 (3%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLC-GPGKC--MNTADS 397 C N C N G C++ E GY CLC PG+ G +C+ SC C G C N + Sbjct: 328 CDSNPCRNGGSCKDQ--EDGYHCLCPPGYYGLHCEHSTLSCADSPCFNGGSCRERNQGAN 385 Query: 398 YKCACPVTYTGKNCEVK 448 Y C CP +TG NCE K Sbjct: 386 YACECPPNFTGSNCEKK 402 Score = 64.1 bits (149), Expect = 3e-10 Identities = 27/75 (36%), Positives = 38/75 (50%), Gaps = 1/75 (1%) Frame = +2 Query: 224 TCAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLC-GPGKCMNTADSY 400 +CA + C N G C+E Y C C P F G+NC++ + C C G+C+N S Sbjct: 365 SCADSPCFNGGSCRERNQGANYACECPPNFTGSNCEKKVDRCTSNPCANGGQCLNRGPSR 424 Query: 401 KCACPVTYTGKNCEV 445 C C +TG CE+ Sbjct: 425 MCRCRPGFTGTYCEL 439 Score = 56.0 bits (129), Expect = 8e-08 Identities = 27/84 (32%), Positives = 36/84 (42%), Gaps = 3/84 (3%) Frame = +2 Query: 242 CLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLC-GPGKCMNTADSYKCACPV 418 C N C + + Y C C PG+ G +C+ C C G C + D Y C CP Sbjct: 294 CKNGATCSNS-GQRSYTCTCRPGYTGVDCELELSECDSNPCRNGGSCKDQEDGYHCLCPP 352 Query: 419 TYTGKNCEVKQL--IEYPAFTGSA 484 Y G +CE L + P F G + Sbjct: 353 GYYGLHCEHSTLSCADSPCFNGGS 376 Score = 54.0 bits (124), Expect = 3e-07 Identities = 25/79 (31%), Positives = 34/79 (43%), Gaps = 1/79 (1%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLCGPG-KCMNTADSYK 403 C N C N G C +C C PGF G C+ C C G C + + Sbjct: 406 CTSNPCANGGQCLNRGPSR--MCRCRPGFTGTYCELHVSDCARNPCAHGGTCHDLENGLM 463 Query: 404 CACPVTYTGKNCEVKQLIE 460 C CP ++G+ CEV+ I+ Sbjct: 464 CTCPAGFSGRRCEVRTSID 482 Score = 49.6 bits (113), Expect = 7e-06 Identities = 25/77 (32%), Positives = 36/77 (46%), Gaps = 5/77 (6%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCD-RIG-ESCRPGLC-GPGKCMN--TA 391 CA N C + G C + E+G +C C GF G C+ R ++C C C + Sbjct: 444 CARNPCAHGGTCHDL--ENGLMCTCPAGFSGRRCEVRTSIDACASSPCFNRATCYTDLST 501 Query: 392 DSYKCACPVTYTGKNCE 442 D++ C CP + G CE Sbjct: 502 DTFVCNCPYGFVGSRCE 518 Score = 44.0 bits (99), Expect = 3e-04 Identities = 24/74 (32%), Positives = 34/74 (45%), Gaps = 3/74 (4%) Frame = +2 Query: 236 NLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESC-RPGLCGPG-KCMNTAD-SYKC 406 N C+ + C+ + C C G+GG CD+ C C G C N+ SY C Sbjct: 251 NECIPHNGCRHGTCSTPWQCTCDEGWGGLFCDQDLNYCTHHSPCKNGATCSNSGQRSYTC 310 Query: 407 ACPVTYTGKNCEVK 448 C YTG +CE++ Sbjct: 311 TCRPGYTGVDCELE 324 Score = 31.1 bits (67), Expect = 2.6 Identities = 17/54 (31%), Positives = 22/54 (40%), Gaps = 3/54 (5%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRI--GESCRPGLCG-PGKC 379 C +CL+ Q CLC PG+ G C+ CR G C P +C Sbjct: 217 CQQPICLSGCHEQNGYCSKPAECLCRPGWQGRLCNECIPHNGCRHGTCSTPWQC 270 >AB036931-1|BAB16085.1| 685|Homo sapiens notch ligand delta-2 protein. Length = 685 Score = 66.1 bits (154), Expect = 7e-11 Identities = 32/77 (41%), Positives = 39/77 (50%), Gaps = 3/77 (3%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLC-GPGKC--MNTADS 397 C N C N G C++ E GY CLC PG+ G +C+ SC C G C N + Sbjct: 328 CDSNPCRNGGSCKDQ--EDGYHCLCPPGYYGLHCEHSTLSCADSPCFNGGSCRERNQGAN 385 Query: 398 YKCACPVTYTGKNCEVK 448 Y C CP +TG NCE K Sbjct: 386 YACECPPNFTGSNCEKK 402 Score = 64.1 bits (149), Expect = 3e-10 Identities = 27/75 (36%), Positives = 38/75 (50%), Gaps = 1/75 (1%) Frame = +2 Query: 224 TCAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLC-GPGKCMNTADSY 400 +CA + C N G C+E Y C C P F G+NC++ + C C G+C+N S Sbjct: 365 SCADSPCFNGGSCRERNQGANYACECPPNFTGSNCEKKVDRCTSNPCANGGQCLNRGPSR 424 Query: 401 KCACPVTYTGKNCEV 445 C C +TG CE+ Sbjct: 425 MCRCRPGFTGTYCEL 439 Score = 56.0 bits (129), Expect = 8e-08 Identities = 27/84 (32%), Positives = 36/84 (42%), Gaps = 3/84 (3%) Frame = +2 Query: 242 CLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLC-GPGKCMNTADSYKCACPV 418 C N C + + Y C C PG+ G +C+ C C G C + D Y C CP Sbjct: 294 CKNGATCSNS-GQRSYTCTCRPGYTGVDCELELSECDSNPCRNGGSCKDQEDGYHCLCPP 352 Query: 419 TYTGKNCEVKQL--IEYPAFTGSA 484 Y G +CE L + P F G + Sbjct: 353 GYYGLHCEHSTLSCADSPCFNGGS 376 Score = 54.0 bits (124), Expect = 3e-07 Identities = 25/79 (31%), Positives = 34/79 (43%), Gaps = 1/79 (1%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLCGPG-KCMNTADSYK 403 C N C N G C +C C PGF G C+ C C G C + + Sbjct: 406 CTSNPCANGGQCLNRGPSR--MCRCRPGFTGTYCELHVSDCARNPCAHGGTCHDLENGLM 463 Query: 404 CACPVTYTGKNCEVKQLIE 460 C CP ++G+ CEV+ I+ Sbjct: 464 CTCPAGFSGRRCEVRTSID 482 Score = 49.6 bits (113), Expect = 7e-06 Identities = 25/77 (32%), Positives = 36/77 (46%), Gaps = 5/77 (6%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCD-RIG-ESCRPGLC-GPGKCMN--TA 391 CA N C + G C + E+G +C C GF G C+ R ++C C C + Sbjct: 444 CARNPCAHGGTCHDL--ENGLMCTCPAGFSGRRCEVRTSIDACASSPCFNRATCYTDLST 501 Query: 392 DSYKCACPVTYTGKNCE 442 D++ C CP + G CE Sbjct: 502 DTFVCNCPYGFVGSRCE 518 Score = 44.0 bits (99), Expect = 3e-04 Identities = 24/74 (32%), Positives = 34/74 (45%), Gaps = 3/74 (4%) Frame = +2 Query: 236 NLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESC-RPGLCGPG-KCMNTAD-SYKC 406 N C+ + C+ + C C G+GG CD+ C C G C N+ SY C Sbjct: 251 NECIPHNGCRHGTCSTPWQCTCDEGWGGLFCDQDLNYCTHHSPCKNGATCSNSGQRSYTC 310 Query: 407 ACPVTYTGKNCEVK 448 C YTG +CE++ Sbjct: 311 TCRPGYTGVDCELE 324 Score = 31.1 bits (67), Expect = 2.6 Identities = 17/54 (31%), Positives = 22/54 (40%), Gaps = 3/54 (5%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRI--GESCRPGLCG-PGKC 379 C +CL+ Q CLC PG+ G C+ CR G C P +C Sbjct: 217 CQQPICLSGCHEQNGYCSKPAECLCRPGWQGRLCNECIPHNGCRHGTCSTPWQC 270 >U95299-1|AAC32288.1| 2003|Homo sapiens Notch4 protein. Length = 2003 Score = 65.7 bits (153), Expect = 1e-10 Identities = 32/105 (30%), Positives = 48/105 (45%), Gaps = 1/105 (0%) Frame = +2 Query: 203 ENVQNCFTCAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLCGPGK-C 379 E+V C T P C N G CQ + + C+C G+GG +C+ + C C PG C Sbjct: 313 EDVDECETQGPPHCRNGGTCQNSAGS--FHCVCVSGWGGTSCEENLDDCIAATCAPGSTC 370 Query: 380 MNTADSYKCACPVTYTGKNCEVKQLIEYPAFTGSA*LAIKPPTST 514 ++ S+ C CP TG C ++ + G A + P T + Sbjct: 371 IDRVGSFSCLCPPGRTGLLCHLEDMCLSQPCHGDAQCSTNPLTGS 415 Score = 64.1 bits (149), Expect = 3e-10 Identities = 31/77 (40%), Positives = 40/77 (51%), Gaps = 3/77 (3%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESC--RPGLCGPG-KCMNTADS 397 C+ N C+N GVC + C C PGF G+ C+R C PG C G C NT S Sbjct: 160 CSANPCVNGGVCLATYPQ--IQCHCPPGFEGHACERDVNECFQDPGPCPKGTSCHNTLGS 217 Query: 398 YKCACPVTYTGKNCEVK 448 ++C CPV G CE++ Sbjct: 218 FQCLCPVGQEGPRCELR 234 Score = 61.3 bits (142), Expect = 2e-09 Identities = 28/74 (37%), Positives = 39/74 (52%), Gaps = 3/74 (4%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHG--YVCLCAPGFGGNNCDRIGESCRPGLC-GPGKCMNTADS 397 C P C N G CQ + ++CLC PGF G +C+ ++C C G C + D+ Sbjct: 238 CPPRGCSNGGTCQLMPEKDSTFHLCLCPPGFIGPDCEVNPDNCVSHQCQNGGTCQDGLDT 297 Query: 398 YKCACPVTYTGKNC 439 Y C CP T+TG +C Sbjct: 298 YTCLCPETWTGWDC 311 Score = 59.7 bits (138), Expect = 6e-09 Identities = 28/89 (31%), Positives = 44/89 (49%), Gaps = 3/89 (3%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLC-GPGKCMNTADSYK 403 CA CLN+ C + L +G+ C+C PGF G C+ + CR C G+C + ++ Sbjct: 517 CASAPCLNHADCHDLL--NGFQCICLPGFSGTRCEEDIDECRSSPCANGGQCQDQPGAFH 574 Query: 404 CACPVTYTGKNC--EVKQLIEYPAFTGSA 484 C C + G C EV + + P G++ Sbjct: 575 CKCLPGFEGPRCQTEVDECLSDPCPVGAS 603 Score = 59.7 bits (138), Expect = 6e-09 Identities = 30/90 (33%), Positives = 43/90 (47%), Gaps = 4/90 (4%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLC-GPGKCMNTADSYK 403 C C N C + GY+C CAPG+ G NC + ++C+ C G C + Sbjct: 934 CESRPCQNGATCMAQPS--GYLCQCAPGYDGQNCSKELDACQSQPCHNHGTCTPKPGGFH 991 Query: 404 CACPVTYTGKNCE--VKQLIEYPAF-TGSA 484 CACP + G CE V + ++ P TG+A Sbjct: 992 CACPPGFVGLRCEGDVDECLDQPCHPTGTA 1021 Score = 57.6 bits (133), Expect = 3e-08 Identities = 29/93 (31%), Positives = 38/93 (40%), Gaps = 8/93 (8%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLCGP------GKCMNT 388 C C + C +CLC PG+ G C + + C GP G C+NT Sbjct: 396 CLSQPCHGDAQCSTNPLTGSTLCLCQPGYSGPTCHQDLDECLMAQQGPSPCEHGGSCLNT 455 Query: 389 ADSYKCACPVTYTGKNCEV--KQLIEYPAFTGS 481 S+ C CP YTG CE + + P GS Sbjct: 456 PGSFNCLCPPGYTGSRCEADHNECLSQPCHPGS 488 Score = 54.0 bits (124), Expect = 3e-07 Identities = 25/74 (33%), Positives = 35/74 (47%), Gaps = 1/74 (1%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLCGPG-KCMNTADSYK 403 C + C N G CQ+ + C C PGF G C + C C G C++ ++ Sbjct: 555 CRSSPCANGGQCQDQ--PGAFHCKCLPGFEGPRCQTEVDECLSDPCPVGASCLDLPGAFF 612 Query: 404 CACPVTYTGKNCEV 445 C CP +TG+ CEV Sbjct: 613 CLCPSGFTGQLCEV 626 Score = 52.8 bits (121), Expect = 7e-07 Identities = 24/73 (32%), Positives = 36/73 (49%), Gaps = 1/73 (1%) Frame = +2 Query: 233 PNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLCGPGK-CMNTADSYKCA 409 P+ C + G C T + CLC PG+ G+ C+ C C PG C++ ++ C Sbjct: 443 PSPCEHGGSCLN--TPGSFNCLCPPGYTGSRCEADHNECLSQPCHPGSTCLDLLATFHCL 500 Query: 410 CPVTYTGKNCEVK 448 CP G+ CEV+ Sbjct: 501 CPPGLEGQLCEVE 513 Score = 52.8 bits (121), Expect = 7e-07 Identities = 26/87 (29%), Positives = 35/87 (40%), Gaps = 3/87 (3%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLC-GPGKCMNTADSYK 403 C C + G C + GY C C G+ G C +C G C G C + Y Sbjct: 695 CISAPCAHGGTCYPQPS--GYNCTCPTGYTGPTCSEEMTACHSGPCLNGGSCNPSPGGYY 752 Query: 404 CACPVTYTGKNCEVK--QLIEYPAFTG 478 C CP ++TG C+ + P F G Sbjct: 753 CTCPPSHTGPQCQTSTDYCVSAPCFNG 779 Score = 51.2 bits (117), Expect = 2e-06 Identities = 26/76 (34%), Positives = 35/76 (46%), Gaps = 4/76 (5%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCR---PGLC-GPGKCMNTAD 394 C + C N G CQ+ L Y CLC + G +C + C P C G C N+A Sbjct: 280 CVSHQCQNGGTCQDGLDT--YTCLCPETWTGWDCSEDVDECETQGPPHCRNGGTCQNSAG 337 Query: 395 SYKCACPVTYTGKNCE 442 S+ C C + G +CE Sbjct: 338 SFHCVCVSGWGGTSCE 353 Score = 51.2 bits (117), Expect = 2e-06 Identities = 24/75 (32%), Positives = 31/75 (41%), Gaps = 1/75 (1%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLC-GPGKCMNTADSYK 403 C CLN G C + GY C C P G C + C C G C+N ++ Sbjct: 733 CHSGPCLNGGSCNPS--PGGYYCTCPPSHTGPQCQTSTDYCVSAPCFNGGTCVNRPGTFS 790 Query: 404 CACPVTYTGKNCEVK 448 C C + + G CE K Sbjct: 791 CLCAMGFQGPRCEGK 805 Score = 50.4 bits (115), Expect = 4e-06 Identities = 25/69 (36%), Positives = 31/69 (44%), Gaps = 1/69 (1%) Frame = +2 Query: 236 NLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLCGPG-KCMNTADSYKCAC 412 +LC N G+C ++ Y C C PGF G+ C C C G CM Y C C Sbjct: 899 SLCHNGGLCVDS--GPSYFCHCPPGFQGSLCQDHVNPCESRPCQNGATCMAQPSGYLCQC 956 Query: 413 PVTYTGKNC 439 Y G+NC Sbjct: 957 APGYDGQNC 965 Score = 50.0 bits (114), Expect = 5e-06 Identities = 24/74 (32%), Positives = 33/74 (44%), Gaps = 2/74 (2%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCD-RIGESCRPGLC-GPGKCMNTADSY 400 C C N G C + CLCA GF G C+ ++ SC C C ++ Sbjct: 771 CVSAPCFNGGTCVNR--PGTFSCLCAMGFQGPRCEGKLRPSCADSPCRNRATCQDSPQGP 828 Query: 401 KCACPVTYTGKNCE 442 +C CP YTG +C+ Sbjct: 829 RCLCPTGYTGGSCQ 842 Score = 50.0 bits (114), Expect = 5e-06 Identities = 23/75 (30%), Positives = 35/75 (46%), Gaps = 1/75 (1%) Frame = +2 Query: 224 TCAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLCGPGK-CMNTADSY 400 +CA + C N CQ++ G CLC G+ G +C + + C C C+ T S+ Sbjct: 809 SCADSPCRNRATCQDS--PQGPRCLCPTGYTGGSCQTLMDLCAQKPCPRNSHCLQTGPSF 866 Query: 401 KCACPVTYTGKNCEV 445 C C +TG C + Sbjct: 867 HCLCLQGWTGPLCNL 881 Score = 49.2 bits (112), Expect = 9e-06 Identities = 28/86 (32%), Positives = 39/86 (45%), Gaps = 7/86 (8%) Frame = +2 Query: 212 QNCF----TCAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLCGP--- 370 QNC C C N+G C G+ C C PGF G C+ + C C P Sbjct: 963 QNCSKELDACQSQPCHNHGTCTPK--PGGFHCACPPGFVGLRCEGDVDECLDQPCHPTGT 1020 Query: 371 GKCMNTADSYKCACPVTYTGKNCEVK 448 C + A+++ C C +TG+ CEV+ Sbjct: 1021 AACHSLANAFYCQCLPGHTGQWCEVE 1046 Score = 46.8 bits (106), Expect = 5e-05 Identities = 22/76 (28%), Positives = 37/76 (48%), Gaps = 4/76 (5%) Frame = +2 Query: 287 YVCLCAPGFGGNNCD-RIGESCRPGLCGP-GKC-MNTADSYKCACPVTYTGKNCEVKQLI 457 ++C C PGF G C ++ + C P C G+C + + +C+C +TG+ C+++ Sbjct: 101 FLCTCLPGFTGERCQAKLEDPCPPSFCSKRGRCHIQASGRPQCSCMPGWTGEQCQLRDFC 160 Query: 458 E-YPAFTGSA*LAIKP 502 P G LA P Sbjct: 161 SANPCVNGGVCLATYP 176 Score = 41.5 bits (93), Expect = 0.002 Identities = 24/75 (32%), Positives = 30/75 (40%), Gaps = 4/75 (5%) Frame = +2 Query: 227 CAP---NLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLCGPG-KCMNTAD 394 CAP N ++G CQ + C+C G+ G C+ C C G C Sbjct: 658 CAPPEDNCTCHHGHCQRSS------CVCDVGWTGPECEAELGGCISAPCAHGGTCYPQPS 711 Query: 395 SYKCACPVTYTGKNC 439 Y C CP YTG C Sbjct: 712 GYNCTCPTGYTGPTC 726 Score = 40.7 bits (91), Expect = 0.003 Identities = 24/74 (32%), Positives = 34/74 (45%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLCGPGKCMNTADSYKC 406 CAPNLC +C++ + CLC G G C ++C C G C ++ C Sbjct: 629 CAPNLCQPKQICKDQKDKAN--CLCPDGSPG--CAPPEDNC---TCHHGHCQRSS----C 677 Query: 407 ACPVTYTGKNCEVK 448 C V +TG CE + Sbjct: 678 VCDVGWTGPECEAE 691 Score = 39.9 bits (89), Expect = 0.006 Identities = 27/87 (31%), Positives = 35/87 (40%), Gaps = 5/87 (5%) Frame = +2 Query: 200 KENVQNCFTCAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLCGPG-- 373 + +V CF P C C L + CLC G G C+ C P C G Sbjct: 192 ERDVNECFQ-DPGPCPKGTSCHNTLGS--FQCLCPVGQEGPRCELRAGPCPPRGCSNGGT 248 Query: 374 -KCMNTADS--YKCACPVTYTGKNCEV 445 + M DS + C CP + G +CEV Sbjct: 249 CQLMPEKDSTFHLCLCPPGFIGPDCEV 275 Score = 39.1 bits (87), Expect = 0.010 Identities = 19/73 (26%), Positives = 28/73 (38%), Gaps = 1/73 (1%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLC-GPGKCMNTADSYK 403 C C C + L + CLC PG G C+ C C C + + ++ Sbjct: 479 CLSQPCHPGSTCLDLLAT--FHCLCPPGLEGQLCEVETNECASAPCLNHADCHDLLNGFQ 536 Query: 404 CACPVTYTGKNCE 442 C C ++G CE Sbjct: 537 CICLPGFSGTRCE 549 Score = 38.7 bits (86), Expect = 0.013 Identities = 24/78 (30%), Positives = 31/78 (39%), Gaps = 7/78 (8%) Frame = +2 Query: 227 CAPNLCLNNGVCQE-ALTEHGYVCLCAPGFGGNNCDRIGESC------RPGLCGPGKCMN 385 C C + G C+ A + G++C C GF G C SC GLC P Sbjct: 1050 CHSQPCFHGGTCEATAGSPLGFICHCPKGFEGPTCSHRAPSCGFHHCHHGGLCLPSP--K 1107 Query: 386 TADSYKCACPVTYTGKNC 439 +CAC Y G +C Sbjct: 1108 PGFPPRCACLSGYGGPDC 1125 Score = 37.9 bits (84), Expect = 0.022 Identities = 27/87 (31%), Positives = 33/87 (37%), Gaps = 15/87 (17%) Frame = +2 Query: 233 PNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCD-----------RIGESCR---PGLCG- 367 P C N G C G C CAPGF G C + G SC+ P G Sbjct: 32 PEPCANGGTCLSLSLGQG-TCQCAPGFLGETCQFPDPCQNAQLCQNGGSCQALLPAPLGL 90 Query: 368 PGKCMNTADSYKCACPVTYTGKNCEVK 448 P S+ C C +TG+ C+ K Sbjct: 91 PSSPSPLTPSFLCTCLPGFTGERCQAK 117 Score = 37.9 bits (84), Expect = 0.022 Identities = 25/83 (30%), Positives = 35/83 (42%), Gaps = 11/83 (13%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPG----------LC-GPG 373 CA C N C + T + CLC G+ G C+ SC+ LC G Sbjct: 848 CAQKPCPRNSHCLQ--TGPSFHCLCLQGWTGPLCNLPLSSCQKAALSQGIDVSSLCHNGG 905 Query: 374 KCMNTADSYKCACPVTYTGKNCE 442 C+++ SY C CP + G C+ Sbjct: 906 LCVDSGPSYFCHCPPGFQGSLCQ 928 Score = 33.9 bits (74), Expect = 0.36 Identities = 21/75 (28%), Positives = 27/75 (36%), Gaps = 4/75 (5%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLC-GPGKCMNTADS-- 397 C C G + + C C PG G C+ + C C G C TA S Sbjct: 1010 CLDQPCHPTGTAACHSLANAFYCQCLPGHTGQWCEVEIDPCHSQPCFHGGTCEATAGSPL 1069 Query: 398 -YKCACPVTYTGKNC 439 + C CP + G C Sbjct: 1070 GFICHCPKGFEGPTC 1084 Score = 33.1 bits (72), Expect = 0.63 Identities = 18/51 (35%), Positives = 21/51 (41%), Gaps = 2/51 (3%) Frame = +2 Query: 233 PNLCLNNGVCQEA--LTEHGYVCLCAPGFGGNNCDRIGESCRPGLCGPGKC 379 P+ CL NG C E L G+ C C G C + G G G G C Sbjct: 1137 PSPCLYNGSCSETTGLGGPGFRCSCPHSSPGPRCQKPGAKGCEGRSGDGAC 1187 Score = 31.9 bits (69), Expect = 1.5 Identities = 23/86 (26%), Positives = 38/86 (44%), Gaps = 13/86 (15%) Frame = +2 Query: 224 TCAPNLCLNNGVCQEALTEHGYV--CLCAPGFGGNNCDRIGESCRPGLCGP-------GK 376 +C + C + G+C + + G+ C C G+GG +C + G CGP G Sbjct: 1090 SCGFHHCHHGGLCLPS-PKPGFPPRCACLSGYGGPDC--LTPPAPKG-CGPPSPCLYNGS 1145 Query: 377 CMNTAD----SYKCACPVTYTGKNCE 442 C T ++C+CP + G C+ Sbjct: 1146 CSETTGLGGPGFRCSCPHSSPGPRCQ 1171 >M73980-1|AAA60614.1| 2444|Homo sapiens TAN1 protein. Length = 2444 Score = 65.7 bits (153), Expect = 1e-10 Identities = 33/83 (39%), Positives = 40/83 (48%), Gaps = 3/83 (3%) Frame = +2 Query: 203 ENVQNCFTCAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESC--RPGLCGPG- 373 ++ Q CA N C N G C E Y+C C P F G C + C +P LC G Sbjct: 136 KSCQQADPCASNPCANGGQCLPF--EASYICHCPPSFHGPTCRQDVNECGQKPRLCRHGG 193 Query: 374 KCMNTADSYKCACPVTYTGKNCE 442 C N SY+C C T+TG NCE Sbjct: 194 TCHNEVGSYRCVCRATHTGPNCE 216 Score = 65.7 bits (153), Expect = 1e-10 Identities = 28/74 (37%), Positives = 39/74 (52%), Gaps = 2/74 (2%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESC--RPGLCGPGKCMNTADSY 400 C + C N G C + + + + CLC PGF G+ C + C RP L G G C + + Sbjct: 988 CTESSCFNGGTCVDGI--NSFTCLCPPGFTGSYCQHVVNECDSRPCLLG-GTCQDGRGLH 1044 Query: 401 KCACPVTYTGKNCE 442 +C CP YTG NC+ Sbjct: 1045 RCTCPQGYTGPNCQ 1058 Score = 64.9 bits (151), Expect = 2e-10 Identities = 29/74 (39%), Positives = 36/74 (48%), Gaps = 1/74 (1%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLC-GPGKCMNTADSYK 403 C N C+N G C++ + G VC C GF G NC C C G C++ YK Sbjct: 757 CESNPCVNGGTCKDMTS--GIVCTCREGFSGPNCQTNINECASNPCLNKGTCIDDVAGYK 814 Query: 404 CACPVTYTGKNCEV 445 C C + YTG CEV Sbjct: 815 CNCLLPYTGATCEV 828 Score = 61.7 bits (143), Expect = 2e-09 Identities = 26/75 (34%), Positives = 36/75 (48%) Frame = +2 Query: 215 NCFTCAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLCGPGKCMNTAD 394 N C+ C G CQ+ ++ Y+C C G G NC+ + C C G C++ D Sbjct: 603 NINECSSQPCRLRGTCQDP--DNAYLCFCLKGTTGPNCEINLDDCASSPCDSGTCLDKID 660 Query: 395 SYKCACPVTYTGKNC 439 Y+CAC YTG C Sbjct: 661 GYECACEPGYTGSMC 675 Score = 60.9 bits (141), Expect = 3e-09 Identities = 25/72 (34%), Positives = 38/72 (52%), Gaps = 1/72 (1%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLC-GPGKCMNTADSYK 403 C+P+ C N G C+ + + C C PGF G NC+ + C C G C++ ++Y Sbjct: 222 CSPSPCQNGGTCRPT-GDVTHECACLPGFTGQNCEENIDDCPGNNCKNGGACVDGVNTYN 280 Query: 404 CACPVTYTGKNC 439 C CP +TG+ C Sbjct: 281 CPCPPEWTGQYC 292 Score = 60.5 bits (140), Expect = 4e-09 Identities = 29/78 (37%), Positives = 41/78 (52%), Gaps = 1/78 (1%) Frame = +2 Query: 215 NCFTCAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLCGPG-KCMNTA 391 N CA + CL+NG C + + E + C C GF G+ C + C C G KC++ Sbjct: 490 NTDECASSPCLHNGRCLDKINE--FQCECPTGFTGHLCQYDVDECASTPCKNGAKCLDGP 547 Query: 392 DSYKCACPVTYTGKNCEV 445 ++Y C C YTG +CEV Sbjct: 548 NTYTCVCTEGYTGTHCEV 565 Score = 60.1 bits (139), Expect = 5e-09 Identities = 30/82 (36%), Positives = 38/82 (46%), Gaps = 5/82 (6%) Frame = +2 Query: 212 QNCFT----CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLCGPG-K 376 +NC T C PN C N G C + + C C PGF G C+ C C G Sbjct: 903 RNCETDIDDCRPNPCHNGGSCTDGINTA--FCDCLPGFRGTFCEEDINECASDPCRNGAN 960 Query: 377 CMNTADSYKCACPVTYTGKNCE 442 C + DSY C CP ++G +CE Sbjct: 961 CTDCVDSYTCTCPAGFSGIHCE 982 Score = 59.3 bits (137), Expect = 8e-09 Identities = 26/74 (35%), Positives = 38/74 (51%), Gaps = 1/74 (1%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLC-GPGKCMNTADSYK 403 C+P+ C N C + L GY C C G+ G NC + C C G C++ ++YK Sbjct: 1150 CSPSPCQNGATCTDYLG--GYSCKCVAGYHGVNCSEEIDECLSHPCQNGGTCLDLPNTYK 1207 Query: 404 CACPVTYTGKNCEV 445 C+CP G +CE+ Sbjct: 1208 CSCPRGTQGVHCEI 1221 Score = 58.8 bits (136), Expect = 1e-08 Identities = 24/77 (31%), Positives = 37/77 (48%) Frame = +2 Query: 215 NCFTCAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLCGPGKCMNTAD 394 N CA N C N G C++ + +G+ C C G+ C C C G C ++ + Sbjct: 678 NIDECAGNPCHNGGTCEDGI--NGFTCRCPEGYHDPTCLSEVNECNSNPCVHGACRDSLN 735 Query: 395 SYKCACPVTYTGKNCEV 445 YKC C ++G NC++ Sbjct: 736 GYKCDCDPGWSGTNCDI 752 Score = 58.0 bits (134), Expect = 2e-08 Identities = 26/74 (35%), Positives = 36/74 (48%), Gaps = 2/74 (2%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLC-APGFGGNNCDRIGESCRPGLCGPG-KCMNTADSY 400 CAP+ C N G C+++ + C+C G G C+ C C G C NT Y Sbjct: 833 CAPSPCRNGGECRQSEDYESFSCVCPTAGAKGQTCEVDINECVLSPCRHGASCQNTHGXY 892 Query: 401 KCACPVTYTGKNCE 442 +C C Y+G+NCE Sbjct: 893 RCHCQAGYSGRNCE 906 Score = 57.2 bits (132), Expect = 3e-08 Identities = 22/73 (30%), Positives = 39/73 (53%), Gaps = 1/73 (1%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLC-GPGKCMNTADSYK 403 C N C N+ C + + E + C+C PG+ G +C+ + C C G+C++ + ++ Sbjct: 456 CVSNPCQNDATCLDQIGE--FQCMCMPGYEGVHCEVNTDECASSPCLHNGRCLDKINEFQ 513 Query: 404 CACPVTYTGKNCE 442 C CP +TG C+ Sbjct: 514 CECPTGFTGHLCQ 526 Score = 56.8 bits (131), Expect = 5e-08 Identities = 27/74 (36%), Positives = 33/74 (44%), Gaps = 1/74 (1%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLC-GPGKCMNTADSYK 403 C CL G CQ+ H C C G+ G NC + C C GKC T Y+ Sbjct: 1026 CDSRPCLLGGTCQDGRGLHR--CTCPQGYTGPNCQNLVHWCDSSPCKNGGKCWQTHTQYR 1083 Query: 404 CACPVTYTGKNCEV 445 C CP +TG C+V Sbjct: 1084 CECPSGWTGLYCDV 1097 Score = 55.2 bits (127), Expect = 1e-07 Identities = 26/72 (36%), Positives = 35/72 (48%), Gaps = 1/72 (1%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLC-GPGKCMNTADSYK 403 C N C N G C + LT Y C C PG+ G +C + + C C G+C+ SY Sbjct: 106 CLTNPCRNGGTC-DLLTLTEYKCRCPPGWSGKSCQQ-ADPCASNPCANGGQCLPFEASYI 163 Query: 404 CACPVTYTGKNC 439 C CP ++ G C Sbjct: 164 CHCPPSFHGPTC 175 Score = 55.2 bits (127), Expect = 1e-07 Identities = 29/83 (34%), Positives = 41/83 (49%), Gaps = 2/83 (2%) Frame = +2 Query: 200 KENVQNCFTCAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLC-GPGK 376 +++V C P LC + G C + Y C+C G NC+R C P C G Sbjct: 176 RQDVNECGQ-KPRLCRHGGTCHNEVGS--YRCVCRATHTGPNCERPYVPCSPSPCQNGGT 232 Query: 377 CMNTAD-SYKCACPVTYTGKNCE 442 C T D +++CAC +TG+NCE Sbjct: 233 CRPTGDVTHECACLPGFTGQNCE 255 Score = 55.2 bits (127), Expect = 1e-07 Identities = 23/72 (31%), Positives = 34/72 (47%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLCGPGKCMNTADSYKC 406 CA C N C + + Y C+C G+ G +C+ + C P C G C + ++ C Sbjct: 532 CASTPCKNGAKCLDG--PNTYTCVCTEGYTGTHCEVDIDECDPDPCHYGSCKDGVATFTC 589 Query: 407 ACPVTYTGKNCE 442 C YTG +CE Sbjct: 590 LCRPGYTGHHCE 601 Score = 55.2 bits (127), Expect = 1e-07 Identities = 25/73 (34%), Positives = 36/73 (49%), Gaps = 1/73 (1%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLC-GPGKCMNTADSYK 403 C N C++ G C+++L +GY C C PG+ G NCD C C G C + Sbjct: 720 CNSNPCVH-GACRDSL--NGYKCDCDPGWSGTNCDINNNECESNPCVNGGTCKDMTSGIV 776 Query: 404 CACPVTYTGKNCE 442 C C ++G NC+ Sbjct: 777 CTCREGFSGPNCQ 789 Score = 55.2 bits (127), Expect = 1e-07 Identities = 24/70 (34%), Positives = 32/70 (45%), Gaps = 3/70 (4%) Frame = +2 Query: 242 CLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLC---GPGKCMNTADSYKCAC 412 C NNG C + + GY C C PGF G C+ C C G C+ + + C C Sbjct: 1239 CFNNGTCVDQVG--GYSCTCPPGFVGERCEGDVNECLSNPCDARGTQNCVQRVNDFHCEC 1296 Query: 413 PVTYTGKNCE 442 +TG+ CE Sbjct: 1297 RAGHTGRRCE 1306 Score = 54.4 bits (125), Expect = 2e-07 Identities = 26/83 (31%), Positives = 39/83 (46%), Gaps = 3/83 (3%) Frame = +2 Query: 239 LCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLCGPG-KCMNTADSYKCACP 415 LC + G+C +A H C C G+ G+ C+ + + C P C G C + Y C C Sbjct: 1116 LCQHGGLCVDAGNTHH--CRCQAGYTGSYCEDLVDECSPSPCQNGATCTDYLGGYSCKCV 1173 Query: 416 VTYTGKNC--EVKQLIEYPAFTG 478 Y G NC E+ + + +P G Sbjct: 1174 AGYHGVNCSEEIDECLSHPCQNG 1196 Score = 54.0 bits (124), Expect = 3e-07 Identities = 29/81 (35%), Positives = 38/81 (46%), Gaps = 4/81 (4%) Frame = +2 Query: 215 NCFTCAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLC-GPGKCMNTA 391 N CA N CLN G C + + GY C C + G C+ + C P C G+C + Sbjct: 791 NINECASNPCLNKGTCIDDVA--GYKCNCLLPYTGATCEVVLAPCAPSPCRNGGECRQSE 848 Query: 392 D--SYKCACPVT-YTGKNCEV 445 D S+ C CP G+ CEV Sbjct: 849 DYESFSCVCPTAGAKGQTCEV 869 Score = 54.0 bits (124), Expect = 3e-07 Identities = 23/73 (31%), Positives = 34/73 (46%), Gaps = 1/73 (1%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLC-GPGKCMNTADSYK 403 CA + C N C + + Y C C GF G +C+ C C G C++ +S+ Sbjct: 950 CASDPCRNGANCTDCVDS--YTCTCPAGFSGIHCENNTPDCTESSCFNGGTCVDGINSFT 1007 Query: 404 CACPVTYTGKNCE 442 C CP +TG C+ Sbjct: 1008 CLCPPGFTGSYCQ 1020 Score = 51.6 bits (118), Expect = 2e-06 Identities = 26/79 (32%), Positives = 35/79 (44%), Gaps = 3/79 (3%) Frame = +2 Query: 212 QNCFTCAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCR--PGLC-GPGKCM 382 +N C N C N G C + + Y C C P + G C + C+ P C G C Sbjct: 256 ENIDDCPGNNCKNGGACVDGVNT--YNCPCPPEWTGQYCTEDVDECQLMPNACQNGGTCH 313 Query: 383 NTADSYKCACPVTYTGKNC 439 NT Y C C +TG++C Sbjct: 314 NTHGGYNCVCVNGWTGEDC 332 Score = 51.2 bits (117), Expect = 2e-06 Identities = 25/76 (32%), Positives = 33/76 (43%), Gaps = 3/76 (3%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGL--CG-PGKCMNTADS 397 C N C C +C C G+ G C + + C G C GKC+NT S Sbjct: 376 CISNPCNEGSNCDTNPVNGKAICTCPSGYTGPACSQDVDECSLGANPCEHAGKCINTLGS 435 Query: 398 YKCACPVTYTGKNCEV 445 ++C C YTG CE+ Sbjct: 436 FECQCLQGYTGPRCEI 451 Score = 50.8 bits (116), Expect = 3e-06 Identities = 24/74 (32%), Positives = 38/74 (51%), Gaps = 1/74 (1%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLCG-PGKCMNTADSYK 403 C P+ C + G C++ + + CLC PG+ G++C+ C C G C + ++Y Sbjct: 570 CDPDPC-HYGSCKDGVAT--FTCLCRPGYTGHHCETNINECSSQPCRLRGTCQDPDNAYL 626 Query: 404 CACPVTYTGKNCEV 445 C C TG NCE+ Sbjct: 627 CFCLKGTTGPNCEI 640 Score = 49.6 bits (113), Expect = 7e-06 Identities = 24/74 (32%), Positives = 32/74 (43%), Gaps = 2/74 (2%) Frame = +2 Query: 227 CAPNLCLNNGVCQEAL-TEHGYVCLCAPGFGGNNCDRIGESCRPGLC-GPGKCMNTADSY 400 C C N G C A T G++C C GF G C+ +C C G C++ S Sbjct: 1312 CKGKPCKNGGTCAVASNTARGFICKCPAGFEGATCENDARTCGSLRCLNGGTCISGPRSP 1371 Query: 401 KCACPVTYTGKNCE 442 C C +TG C+ Sbjct: 1372 TCLCLGPFTGPECQ 1385 Score = 48.4 bits (110), Expect = 2e-05 Identities = 27/92 (29%), Positives = 41/92 (44%), Gaps = 3/92 (3%) Frame = +2 Query: 215 NCFTCAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLC-GPGKCMNTA 391 N CA + C ++G C + + GY C C PG+ G+ C+ + C C G C + Sbjct: 641 NLDDCASSPC-DSGTCLDKID--GYECACEPGYTGSMCNSNIDECAGNPCHNGGTCEDGI 697 Query: 392 DSYKCACPVTYTGKNC--EVKQLIEYPAFTGS 481 + + C CP Y C EV + P G+ Sbjct: 698 NGFTCRCPEGYHDPTCLSEVNECNSNPCVHGA 729 Score = 46.8 bits (106), Expect = 5e-05 Identities = 27/78 (34%), Positives = 35/78 (44%), Gaps = 6/78 (7%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHG---YVCLCAPGFGGNNC-DRIGESCRPGLC-GPGKC-MNT 388 C C N G C + G Y C CA GF G C + +C C G C + T Sbjct: 63 CLSTPCKNAGTCH-VVDRRGVADYACSCALGFSGPLCLTPLDNACLTNPCRNGGTCDLLT 121 Query: 389 ADSYKCACPVTYTGKNCE 442 YKC CP ++GK+C+ Sbjct: 122 LTEYKCRCPPGWSGKSCQ 139 Score = 46.8 bits (106), Expect = 5e-05 Identities = 23/73 (31%), Positives = 32/73 (43%), Gaps = 1/73 (1%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLC-GPGKCMNTADSYK 403 C + C + CQ T Y C C G+ G NC+ + CRP C G C + ++ Sbjct: 874 CVLSPCRHGASCQN--THGXYRCHCQAGYSGRNCETDIDDCRPNPCHNGGSCTDGINTAF 931 Query: 404 CACPVTYTGKNCE 442 C C + G CE Sbjct: 932 CDCLPGFRGTFCE 944 Score = 45.6 bits (103), Expect = 1e-04 Identities = 34/99 (34%), Positives = 42/99 (42%), Gaps = 5/99 (5%) Frame = +2 Query: 224 TCAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGES-CRPGL-C-GPGKCMNTAD 394 TC CLN G C CLC F G C S C G C G C T++ Sbjct: 1352 TCGSLRCLNGGTCISG--PRSPTCLCLGPFTGPECQFPASSPCLGGNPCYNQGTCEPTSE 1409 Query: 395 S--YKCACPVTYTGKNCEVKQLIEYPAFTGSA*LAIKPP 505 S Y+C CP + G C + ++Y +F G A I PP Sbjct: 1410 SPFYRCLCPAKFNGLLCHI---LDY-SFGGGAGRDIPPP 1444 Score = 43.2 bits (97), Expect = 6e-04 Identities = 31/91 (34%), Positives = 40/91 (43%), Gaps = 12/91 (13%) Frame = +2 Query: 206 NVQNCFT-CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESC-----RPG--- 358 N QN C + C N G C + T+ Y C C G+ G CD SC R G Sbjct: 1056 NCQNLVHWCDSSPCKNGGKCWQTHTQ--YRCECPSGWTGLYCDVPSVSCEVAAQRQGVDV 1113 Query: 359 --LCGPGK-CMNTADSYKCACPVTYTGKNCE 442 LC G C++ +++ C C YTG CE Sbjct: 1114 ARLCQHGGLCVDAGNTHHCRCQAGYTGSYCE 1144 Score = 43.2 bits (97), Expect = 6e-04 Identities = 23/81 (28%), Positives = 34/81 (41%), Gaps = 9/81 (11%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGL--------C-GPGKC 379 C + C N G C + + Y C C G G +C+ + C P + C G C Sbjct: 1188 CLSHPCQNGGTCLDL--PNTYKCSCPRGTQGVHCEINVDDCNPPVDPVSRSPKCFNNGTC 1245 Query: 380 MNTADSYKCACPVTYTGKNCE 442 ++ Y C CP + G+ CE Sbjct: 1246 VDQVGGYSCTCPPGFVGERCE 1266 Score = 41.1 bits (92), Expect = 0.002 Identities = 22/76 (28%), Positives = 29/76 (38%), Gaps = 4/76 (5%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLC-GPGKC---MNTAD 394 C N C G + + C C G G C+ + C+ C G C NTA Sbjct: 1272 CLSNPCDARGTQNCVQRVNDFHCECRAGHTGRRCESVINGCKGKPCKNGGTCAVASNTAR 1331 Query: 395 SYKCACPVTYTGKNCE 442 + C CP + G CE Sbjct: 1332 GFICKCPAGFEGATCE 1347 Score = 40.3 bits (90), Expect = 0.004 Identities = 22/82 (26%), Positives = 34/82 (41%), Gaps = 1/82 (1%) Frame = +2 Query: 203 ENVQNCFTCAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLC-GPGKC 379 ++V C + N C + G C L + C C G+ G C+ C C C Sbjct: 411 QDVDEC-SLGANPCEHAGKCINTLGS--FECQCLQGYTGPRCEIDVNECVSNPCQNDATC 467 Query: 380 MNTADSYKCACPVTYTGKNCEV 445 ++ ++C C Y G +CEV Sbjct: 468 LDQIGEFQCMCMPGYEGVHCEV 489 Score = 32.3 bits (70), Expect = 1.1 Identities = 21/71 (29%), Positives = 29/71 (40%), Gaps = 5/71 (7%) Frame = +2 Query: 242 CLNNGVCQEALTEHGYVCLCAPGFGGNNCDR----IGESCR-PGLCGPGKCMNTADSYKC 406 CLN G C+ A C+C F G C + C+ G C AD Y C Sbjct: 31 CLNGGKCEAA--NGTEACVCGGAFVGPRCQDPNPCLSTPCKNAGTCHVVDRRGVAD-YAC 87 Query: 407 ACPVTYTGKNC 439 +C + ++G C Sbjct: 88 SCALGFSGPLC 98 >D86566-1|BAA13116.1| 955|Homo sapiens notch related protein protein. Length = 955 Score = 65.7 bits (153), Expect = 1e-10 Identities = 32/105 (30%), Positives = 48/105 (45%), Gaps = 1/105 (0%) Frame = +2 Query: 203 ENVQNCFTCAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLCGPGK-C 379 E+V C T P C N G CQ + + C+C G+GG +C+ + C C PG C Sbjct: 313 EDVDECETQGPPHCRNGGTCQNSAGS--FHCVCVSGWGGTSCEENLDDCIAATCAPGSTC 370 Query: 380 MNTADSYKCACPVTYTGKNCEVKQLIEYPAFTGSA*LAIKPPTST 514 ++ S+ C CP TG C ++ + G A + P T + Sbjct: 371 IDRVGSFSCLCPPGRTGLLCHLEDMCLSQPCHGDAQCSTNPLTGS 415 Score = 64.1 bits (149), Expect = 3e-10 Identities = 31/77 (40%), Positives = 40/77 (51%), Gaps = 3/77 (3%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESC--RPGLCGPG-KCMNTADS 397 C+ N C+N GVC + C C PGF G+ C+R C PG C G C NT S Sbjct: 160 CSANPCVNGGVCLATYPQ--IQCHCPPGFEGHACERDVNECFQDPGPCPKGTSCHNTLGS 217 Query: 398 YKCACPVTYTGKNCEVK 448 ++C CPV G CE++ Sbjct: 218 FQCLCPVGQEGPRCELR 234 Score = 61.3 bits (142), Expect = 2e-09 Identities = 28/74 (37%), Positives = 39/74 (52%), Gaps = 3/74 (4%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHG--YVCLCAPGFGGNNCDRIGESCRPGLC-GPGKCMNTADS 397 C P C N G CQ + ++CLC PGF G +C+ ++C C G C + D+ Sbjct: 238 CPPRGCSNGGTCQLMPEKDSTFHLCLCPPGFIGPDCEVNPDNCVSHQCQNGGTCQDGLDT 297 Query: 398 YKCACPVTYTGKNC 439 Y C CP T+TG +C Sbjct: 298 YTCLCPETWTGWDC 311 Score = 59.7 bits (138), Expect = 6e-09 Identities = 28/89 (31%), Positives = 44/89 (49%), Gaps = 3/89 (3%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLC-GPGKCMNTADSYK 403 CA CLN+ C + L +G+ C+C PGF G C+ + CR C G+C + ++ Sbjct: 517 CASAPCLNHADCHDLL--NGFQCICLPGFSGTRCEEDIDECRSSPCANGGQCQDQPGAFH 574 Query: 404 CACPVTYTGKNC--EVKQLIEYPAFTGSA 484 C C + G C EV + + P G++ Sbjct: 575 CKCLPGFEGPRCQTEVDECLSDPCPVGAS 603 Score = 57.6 bits (133), Expect = 3e-08 Identities = 29/93 (31%), Positives = 38/93 (40%), Gaps = 8/93 (8%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLCGP------GKCMNT 388 C C + C +CLC PG+ G C + + C GP G C+NT Sbjct: 396 CLSQPCHGDAQCSTNPLTGSTLCLCQPGYSGPTCHQDLDECLMAQQGPSPCEHGGSCLNT 455 Query: 389 ADSYKCACPVTYTGKNCEV--KQLIEYPAFTGS 481 S+ C CP YTG CE + + P GS Sbjct: 456 PGSFNCLCPPGYTGSRCEADHNECLSQPCHPGS 488 Score = 54.0 bits (124), Expect = 3e-07 Identities = 25/74 (33%), Positives = 35/74 (47%), Gaps = 1/74 (1%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLCGPG-KCMNTADSYK 403 C + C N G CQ+ + C C PGF G C + C C G C++ ++ Sbjct: 555 CRSSPCANGGQCQDQ--PGAFHCKCLPGFEGPRCQTEVDECLSDPCPVGASCLDLPGAFF 612 Query: 404 CACPVTYTGKNCEV 445 C CP +TG+ CEV Sbjct: 613 CLCPSGFTGQLCEV 626 Score = 52.8 bits (121), Expect = 7e-07 Identities = 24/73 (32%), Positives = 36/73 (49%), Gaps = 1/73 (1%) Frame = +2 Query: 233 PNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLCGPGK-CMNTADSYKCA 409 P+ C + G C T + CLC PG+ G+ C+ C C PG C++ ++ C Sbjct: 443 PSPCEHGGSCLN--TPGSFNCLCPPGYTGSRCEADHNECLSQPCHPGSTCLDLLATFHCL 500 Query: 410 CPVTYTGKNCEVK 448 CP G+ CEV+ Sbjct: 501 CPPGLEGQLCEVE 513 Score = 52.8 bits (121), Expect = 7e-07 Identities = 26/87 (29%), Positives = 35/87 (40%), Gaps = 3/87 (3%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLC-GPGKCMNTADSYK 403 C C + G C + GY C C G+ G C +C G C G C + Y Sbjct: 695 CISAPCAHGGTCYPQPS--GYNCTCPTGYTGPTCSEEMTACHSGPCLNGGSCNPSPGGYY 752 Query: 404 CACPVTYTGKNCEVK--QLIEYPAFTG 478 C CP ++TG C+ + P F G Sbjct: 753 CTCPPSHTGPQCQTSTDYCVSAPCFNG 779 Score = 51.2 bits (117), Expect = 2e-06 Identities = 26/76 (34%), Positives = 35/76 (46%), Gaps = 4/76 (5%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCR---PGLC-GPGKCMNTAD 394 C + C N G CQ+ L Y CLC + G +C + C P C G C N+A Sbjct: 280 CVSHQCQNGGTCQDGLDT--YTCLCPETWTGWDCSEDVDECETQGPPHCRNGGTCQNSAG 337 Query: 395 SYKCACPVTYTGKNCE 442 S+ C C + G +CE Sbjct: 338 SFHCVCVSGWGGTSCE 353 Score = 51.2 bits (117), Expect = 2e-06 Identities = 24/75 (32%), Positives = 31/75 (41%), Gaps = 1/75 (1%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLC-GPGKCMNTADSYK 403 C CLN G C + GY C C P G C + C C G C+N ++ Sbjct: 733 CHSGPCLNGGSCNPS--PGGYYCTCPPSHTGPQCQTSTDYCVSAPCFNGGTCVNRPGTFS 790 Query: 404 CACPVTYTGKNCEVK 448 C C + + G CE K Sbjct: 791 CLCAMGFQGPRCEGK 805 Score = 50.0 bits (114), Expect = 5e-06 Identities = 24/74 (32%), Positives = 33/74 (44%), Gaps = 2/74 (2%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCD-RIGESCRPGLC-GPGKCMNTADSY 400 C C N G C + CLCA GF G C+ ++ SC C C ++ Sbjct: 771 CVSAPCFNGGTCVNR--PGTFSCLCAMGFQGPRCEGKLRPSCADSPCRNRATCQDSPQGP 828 Query: 401 KCACPVTYTGKNCE 442 +C CP YTG +C+ Sbjct: 829 RCLCPTGYTGGSCQ 842 Score = 50.0 bits (114), Expect = 5e-06 Identities = 23/75 (30%), Positives = 35/75 (46%), Gaps = 1/75 (1%) Frame = +2 Query: 224 TCAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLCGPGK-CMNTADSY 400 +CA + C N CQ++ G CLC G+ G +C + + C C C+ T S+ Sbjct: 809 SCADSPCRNRATCQDS--PQGPRCLCPTGYTGGSCQTLMDLCAQRPCPRNSHCLQTGPSF 866 Query: 401 KCACPVTYTGKNCEV 445 C C +TG C + Sbjct: 867 HCLCLQGWTGPLCNL 881 Score = 46.4 bits (105), Expect = 6e-05 Identities = 22/76 (28%), Positives = 37/76 (48%), Gaps = 4/76 (5%) Frame = +2 Query: 287 YVCLCAPGFGGNNCD-RIGESCRPGLCGP-GKC-MNTADSYKCACPVTYTGKNCEVKQLI 457 ++C C PGF G C ++ + C P C G+C + + +C+C +TG+ C+++ Sbjct: 101 FLCTCLPGFTGERCQAQLEDPCPPSFCSKRGRCHIQASGRPQCSCMPGWTGEQCQLRDFC 160 Query: 458 E-YPAFTGSA*LAIKP 502 P G LA P Sbjct: 161 SANPCVNGGVCLATYP 176 Score = 41.5 bits (93), Expect = 0.002 Identities = 24/75 (32%), Positives = 30/75 (40%), Gaps = 4/75 (5%) Frame = +2 Query: 227 CAP---NLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLCGPG-KCMNTAD 394 CAP N ++G CQ + C+C G+ G C+ C C G C Sbjct: 658 CAPPEDNCTCHHGHCQRSS------CVCDVGWTGPECEAELGGCISAPCAHGGTCYPQPS 711 Query: 395 SYKCACPVTYTGKNC 439 Y C CP YTG C Sbjct: 712 GYNCTCPTGYTGPTC 726 Score = 40.7 bits (91), Expect = 0.003 Identities = 24/74 (32%), Positives = 34/74 (45%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLCGPGKCMNTADSYKC 406 CAPNLC +C++ + CLC G G C ++C C G C ++ C Sbjct: 629 CAPNLCQPKQICKDQKDKAN--CLCPDGSPG--CAPPEDNC---TCHHGHCQRSS----C 677 Query: 407 ACPVTYTGKNCEVK 448 C V +TG CE + Sbjct: 678 VCDVGWTGPECEAE 691 Score = 39.9 bits (89), Expect = 0.006 Identities = 27/87 (31%), Positives = 35/87 (40%), Gaps = 5/87 (5%) Frame = +2 Query: 200 KENVQNCFTCAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLCGPG-- 373 + +V CF P C C L + CLC G G C+ C P C G Sbjct: 192 ERDVNECFQ-DPGPCPKGTSCHNTLGS--FQCLCPVGQEGPRCELRAGPCPPRGCSNGGT 248 Query: 374 -KCMNTADS--YKCACPVTYTGKNCEV 445 + M DS + C CP + G +CEV Sbjct: 249 CQLMPEKDSTFHLCLCPPGFIGPDCEV 275 Score = 39.1 bits (87), Expect = 0.010 Identities = 19/73 (26%), Positives = 28/73 (38%), Gaps = 1/73 (1%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLC-GPGKCMNTADSYK 403 C C C + L + CLC PG G C+ C C C + + ++ Sbjct: 479 CLSQPCHPGSTCLDLLAT--FHCLCPPGLEGQLCEVETNECASAPCLNHADCHDLLNGFQ 536 Query: 404 CACPVTYTGKNCE 442 C C ++G CE Sbjct: 537 CICLPGFSGTRCE 549 Score = 37.9 bits (84), Expect = 0.022 Identities = 25/83 (30%), Positives = 35/83 (42%), Gaps = 11/83 (13%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPG----------LC-GPG 373 CA C N C + T + CLC G+ G C+ SC+ LC G Sbjct: 848 CAQRPCPRNSHCLQ--TGPSFHCLCLQGWTGPLCNLPLSSCQKAALSQGIDVSSLCHNGG 905 Query: 374 KCMNTADSYKCACPVTYTGKNCE 442 C+++ SY C CP + G C+ Sbjct: 906 LCVDSGPSYFCHCPPGFQGSLCQ 928 Score = 37.9 bits (84), Expect = 0.022 Identities = 20/58 (34%), Positives = 25/58 (43%), Gaps = 1/58 (1%) Frame = +2 Query: 236 NLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLCGPG-KCMNTADSYKC 406 +LC N G+C ++ Y C C PGF G+ C C C G CM Y C Sbjct: 899 SLCHNGGLCVDS--GPSYFCHCPPGFQGSLCQDHVNPCESRPCQNGATCMAQPSGYLC 954 Score = 36.3 bits (80), Expect = 0.068 Identities = 26/87 (29%), Positives = 33/87 (37%), Gaps = 15/87 (17%) Frame = +2 Query: 233 PNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCD-----------RIGESCR---PGLCG- 367 P C N G C G C CAPGF G C + G SC+ P G Sbjct: 32 PEPCANGGTCLSLSLGQG-TCQCAPGFLGETCQFPDPCQNAQLCQNGGSCQALLPAPLGL 90 Query: 368 PGKCMNTADSYKCACPVTYTGKNCEVK 448 P S+ C C +TG+ C+ + Sbjct: 91 PSSPSPLTPSFLCTCLPGFTGERCQAQ 117 >BX284927-1|CAM25850.1| 2003|Homo sapiens Notch homolog 4 (Drosophila) protein. Length = 2003 Score = 65.7 bits (153), Expect = 1e-10 Identities = 32/105 (30%), Positives = 48/105 (45%), Gaps = 1/105 (0%) Frame = +2 Query: 203 ENVQNCFTCAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLCGPGK-C 379 E+V C T P C N G CQ + + C+C G+GG +C+ + C C PG C Sbjct: 313 EDVDECETQGPPHCRNGGTCQNSAGS--FHCVCVSGWGGTSCEENLDDCIAATCAPGSTC 370 Query: 380 MNTADSYKCACPVTYTGKNCEVKQLIEYPAFTGSA*LAIKPPTST 514 ++ S+ C CP TG C ++ + G A + P T + Sbjct: 371 IDRVGSFSCLCPPGRTGLLCHLEDMCLSQPCHGDAQCSTNPLTGS 415 Score = 64.1 bits (149), Expect = 3e-10 Identities = 31/77 (40%), Positives = 40/77 (51%), Gaps = 3/77 (3%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESC--RPGLCGPG-KCMNTADS 397 C+ N C+N GVC + C C PGF G+ C+R C PG C G C NT S Sbjct: 160 CSANPCVNGGVCLATYPQ--IQCHCPPGFEGHACERDVNECFQDPGPCPKGTSCHNTLGS 217 Query: 398 YKCACPVTYTGKNCEVK 448 ++C CPV G CE++ Sbjct: 218 FQCLCPVGQEGPRCELR 234 Score = 61.3 bits (142), Expect = 2e-09 Identities = 28/74 (37%), Positives = 39/74 (52%), Gaps = 3/74 (4%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHG--YVCLCAPGFGGNNCDRIGESCRPGLC-GPGKCMNTADS 397 C P C N G CQ + ++CLC PGF G +C+ ++C C G C + D+ Sbjct: 238 CPPRGCSNGGTCQLMPEKDSTFHLCLCPPGFIGPDCEVNPDNCVSHQCQNGGTCQDGLDT 297 Query: 398 YKCACPVTYTGKNC 439 Y C CP T+TG +C Sbjct: 298 YTCLCPETWTGWDC 311 Score = 59.7 bits (138), Expect = 6e-09 Identities = 28/89 (31%), Positives = 44/89 (49%), Gaps = 3/89 (3%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLC-GPGKCMNTADSYK 403 CA CLN+ C + L +G+ C+C PGF G C+ + CR C G+C + ++ Sbjct: 517 CASAPCLNHADCHDLL--NGFQCICLPGFSGTRCEEDIDECRSSPCANGGQCQDQPGAFH 574 Query: 404 CACPVTYTGKNC--EVKQLIEYPAFTGSA 484 C C + G C EV + + P G++ Sbjct: 575 CKCLPGFEGPRCQTEVDECLSDPCPVGAS 603 Score = 59.7 bits (138), Expect = 6e-09 Identities = 30/90 (33%), Positives = 43/90 (47%), Gaps = 4/90 (4%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLC-GPGKCMNTADSYK 403 C C N C + GY+C CAPG+ G NC + ++C+ C G C + Sbjct: 934 CESRPCQNGATCMAQPS--GYLCQCAPGYDGQNCSKELDACQSQPCHNHGTCTPKPGGFH 991 Query: 404 CACPVTYTGKNCE--VKQLIEYPAF-TGSA 484 CACP + G CE V + ++ P TG+A Sbjct: 992 CACPPGFVGLRCEGDVDECLDQPCHPTGTA 1021 Score = 57.6 bits (133), Expect = 3e-08 Identities = 29/93 (31%), Positives = 38/93 (40%), Gaps = 8/93 (8%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLCGP------GKCMNT 388 C C + C +CLC PG+ G C + + C GP G C+NT Sbjct: 396 CLSQPCHGDAQCSTNPLTGSTLCLCQPGYSGPTCHQDLDECLMAQQGPSPCEHGGSCLNT 455 Query: 389 ADSYKCACPVTYTGKNCEV--KQLIEYPAFTGS 481 S+ C CP YTG CE + + P GS Sbjct: 456 PGSFNCLCPPGYTGSRCEADHNECLSQPCHPGS 488 Score = 54.0 bits (124), Expect = 3e-07 Identities = 25/74 (33%), Positives = 35/74 (47%), Gaps = 1/74 (1%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLCGPG-KCMNTADSYK 403 C + C N G CQ+ + C C PGF G C + C C G C++ ++ Sbjct: 555 CRSSPCANGGQCQDQ--PGAFHCKCLPGFEGPRCQTEVDECLSDPCPVGASCLDLPGAFF 612 Query: 404 CACPVTYTGKNCEV 445 C CP +TG+ CEV Sbjct: 613 CLCPSGFTGQLCEV 626 Score = 52.8 bits (121), Expect = 7e-07 Identities = 24/73 (32%), Positives = 36/73 (49%), Gaps = 1/73 (1%) Frame = +2 Query: 233 PNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLCGPGK-CMNTADSYKCA 409 P+ C + G C T + CLC PG+ G+ C+ C C PG C++ ++ C Sbjct: 443 PSPCEHGGSCLN--TPGSFNCLCPPGYTGSRCEADHNECLSQPCHPGSTCLDLLATFHCL 500 Query: 410 CPVTYTGKNCEVK 448 CP G+ CEV+ Sbjct: 501 CPPGLEGQLCEVE 513 Score = 52.8 bits (121), Expect = 7e-07 Identities = 26/87 (29%), Positives = 35/87 (40%), Gaps = 3/87 (3%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLC-GPGKCMNTADSYK 403 C C + G C + GY C C G+ G C +C G C G C + Y Sbjct: 695 CISAPCAHGGTCYPQPS--GYNCTCPTGYTGPTCSEEMTACHSGPCLNGGSCNPSPGGYY 752 Query: 404 CACPVTYTGKNCEVK--QLIEYPAFTG 478 C CP ++TG C+ + P F G Sbjct: 753 CTCPPSHTGPQCQTSTDYCVSAPCFNG 779 Score = 51.2 bits (117), Expect = 2e-06 Identities = 26/76 (34%), Positives = 35/76 (46%), Gaps = 4/76 (5%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCR---PGLC-GPGKCMNTAD 394 C + C N G CQ+ L Y CLC + G +C + C P C G C N+A Sbjct: 280 CVSHQCQNGGTCQDGLDT--YTCLCPETWTGWDCSEDVDECETQGPPHCRNGGTCQNSAG 337 Query: 395 SYKCACPVTYTGKNCE 442 S+ C C + G +CE Sbjct: 338 SFHCVCVSGWGGTSCE 353 Score = 51.2 bits (117), Expect = 2e-06 Identities = 24/75 (32%), Positives = 31/75 (41%), Gaps = 1/75 (1%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLC-GPGKCMNTADSYK 403 C CLN G C + GY C C P G C + C C G C+N ++ Sbjct: 733 CHSGPCLNGGSCNPS--PGGYYCTCPPSHTGPQCQTSTDYCVSAPCFNGGTCVNRPGTFS 790 Query: 404 CACPVTYTGKNCEVK 448 C C + + G CE K Sbjct: 791 CLCAMGFQGPRCEGK 805 Score = 50.4 bits (115), Expect = 4e-06 Identities = 25/69 (36%), Positives = 31/69 (44%), Gaps = 1/69 (1%) Frame = +2 Query: 236 NLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLCGPG-KCMNTADSYKCAC 412 +LC N G+C ++ Y C C PGF G+ C C C G CM Y C C Sbjct: 899 SLCHNGGLCVDS--GPSYFCHCPPGFQGSLCQDHVNPCESRPCQNGATCMAQPSGYLCQC 956 Query: 413 PVTYTGKNC 439 Y G+NC Sbjct: 957 APGYDGQNC 965 Score = 50.0 bits (114), Expect = 5e-06 Identities = 24/74 (32%), Positives = 33/74 (44%), Gaps = 2/74 (2%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCD-RIGESCRPGLC-GPGKCMNTADSY 400 C C N G C + CLCA GF G C+ ++ SC C C ++ Sbjct: 771 CVSAPCFNGGTCVNR--PGTFSCLCAMGFQGPRCEGKLRPSCADSPCRNRATCQDSPQGP 828 Query: 401 KCACPVTYTGKNCE 442 +C CP YTG +C+ Sbjct: 829 RCLCPTGYTGGSCQ 842 Score = 50.0 bits (114), Expect = 5e-06 Identities = 23/75 (30%), Positives = 35/75 (46%), Gaps = 1/75 (1%) Frame = +2 Query: 224 TCAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLCGPGK-CMNTADSY 400 +CA + C N CQ++ G CLC G+ G +C + + C C C+ T S+ Sbjct: 809 SCADSPCRNRATCQDS--PQGPRCLCPTGYTGGSCQTLMDLCAQKPCPRNSHCLQTGPSF 866 Query: 401 KCACPVTYTGKNCEV 445 C C +TG C + Sbjct: 867 HCLCLQGWTGPLCNL 881 Score = 49.2 bits (112), Expect = 9e-06 Identities = 28/86 (32%), Positives = 39/86 (45%), Gaps = 7/86 (8%) Frame = +2 Query: 212 QNCF----TCAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLCGP--- 370 QNC C C N+G C G+ C C PGF G C+ + C C P Sbjct: 963 QNCSKELDACQSQPCHNHGTCTPK--PGGFHCACPPGFVGLRCEGDVDECLDQPCHPTGT 1020 Query: 371 GKCMNTADSYKCACPVTYTGKNCEVK 448 C + A+++ C C +TG+ CEV+ Sbjct: 1021 AACHSLANAFYCQCLPGHTGQWCEVE 1046 Score = 46.8 bits (106), Expect = 5e-05 Identities = 22/76 (28%), Positives = 37/76 (48%), Gaps = 4/76 (5%) Frame = +2 Query: 287 YVCLCAPGFGGNNCD-RIGESCRPGLCGP-GKC-MNTADSYKCACPVTYTGKNCEVKQLI 457 ++C C PGF G C ++ + C P C G+C + + +C+C +TG+ C+++ Sbjct: 101 FLCTCLPGFTGERCQAKLEDPCPPSFCSKRGRCHIQASGRPQCSCMPGWTGEQCQLRDFC 160 Query: 458 E-YPAFTGSA*LAIKP 502 P G LA P Sbjct: 161 SANPCVNGGVCLATYP 176 Score = 41.5 bits (93), Expect = 0.002 Identities = 24/75 (32%), Positives = 30/75 (40%), Gaps = 4/75 (5%) Frame = +2 Query: 227 CAP---NLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLCGPG-KCMNTAD 394 CAP N ++G CQ + C+C G+ G C+ C C G C Sbjct: 658 CAPPEDNCTCHHGHCQRSS------CVCDVGWTGPECEAELGGCISAPCAHGGTCYPQPS 711 Query: 395 SYKCACPVTYTGKNC 439 Y C CP YTG C Sbjct: 712 GYNCTCPTGYTGPTC 726 Score = 40.7 bits (91), Expect = 0.003 Identities = 24/74 (32%), Positives = 34/74 (45%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLCGPGKCMNTADSYKC 406 CAPNLC +C++ + CLC G G C ++C C G C ++ C Sbjct: 629 CAPNLCQPKQICKDQKDKAN--CLCPDGSPG--CAPPEDNC---TCHHGHCQRSS----C 677 Query: 407 ACPVTYTGKNCEVK 448 C V +TG CE + Sbjct: 678 VCDVGWTGPECEAE 691 Score = 39.9 bits (89), Expect = 0.006 Identities = 27/87 (31%), Positives = 35/87 (40%), Gaps = 5/87 (5%) Frame = +2 Query: 200 KENVQNCFTCAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLCGPG-- 373 + +V CF P C C L + CLC G G C+ C P C G Sbjct: 192 ERDVNECFQ-DPGPCPKGTSCHNTLGS--FQCLCPVGQEGPRCELRAGPCPPRGCSNGGT 248 Query: 374 -KCMNTADS--YKCACPVTYTGKNCEV 445 + M DS + C CP + G +CEV Sbjct: 249 CQLMPEKDSTFHLCLCPPGFIGPDCEV 275 Score = 39.1 bits (87), Expect = 0.010 Identities = 19/73 (26%), Positives = 28/73 (38%), Gaps = 1/73 (1%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLC-GPGKCMNTADSYK 403 C C C + L + CLC PG G C+ C C C + + ++ Sbjct: 479 CLSQPCHPGSTCLDLLAT--FHCLCPPGLEGQLCEVETNECASAPCLNHADCHDLLNGFQ 536 Query: 404 CACPVTYTGKNCE 442 C C ++G CE Sbjct: 537 CICLPGFSGTRCE 549 Score = 38.7 bits (86), Expect = 0.013 Identities = 24/78 (30%), Positives = 31/78 (39%), Gaps = 7/78 (8%) Frame = +2 Query: 227 CAPNLCLNNGVCQE-ALTEHGYVCLCAPGFGGNNCDRIGESC------RPGLCGPGKCMN 385 C C + G C+ A + G++C C GF G C SC GLC P Sbjct: 1050 CHSQPCFHGGTCEATAGSPLGFICHCPKGFEGPTCSHRAPSCGFHHCHHGGLCLPSP--K 1107 Query: 386 TADSYKCACPVTYTGKNC 439 +CAC Y G +C Sbjct: 1108 PGFPPRCACLSGYGGPDC 1125 Score = 37.9 bits (84), Expect = 0.022 Identities = 27/87 (31%), Positives = 33/87 (37%), Gaps = 15/87 (17%) Frame = +2 Query: 233 PNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCD-----------RIGESCR---PGLCG- 367 P C N G C G C CAPGF G C + G SC+ P G Sbjct: 32 PEPCANGGTCLSLSLGQG-TCQCAPGFLGETCQFPDPCQNAQLCQNGGSCQALLPAPLGL 90 Query: 368 PGKCMNTADSYKCACPVTYTGKNCEVK 448 P S+ C C +TG+ C+ K Sbjct: 91 PSSPSPLTPSFLCTCLPGFTGERCQAK 117 Score = 37.9 bits (84), Expect = 0.022 Identities = 25/83 (30%), Positives = 35/83 (42%), Gaps = 11/83 (13%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPG----------LC-GPG 373 CA C N C + T + CLC G+ G C+ SC+ LC G Sbjct: 848 CAQKPCPRNSHCLQ--TGPSFHCLCLQGWTGPLCNLPLSSCQKAALSQGIDVSSLCHNGG 905 Query: 374 KCMNTADSYKCACPVTYTGKNCE 442 C+++ SY C CP + G C+ Sbjct: 906 LCVDSGPSYFCHCPPGFQGSLCQ 928 Score = 33.9 bits (74), Expect = 0.36 Identities = 21/75 (28%), Positives = 27/75 (36%), Gaps = 4/75 (5%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLC-GPGKCMNTADS-- 397 C C G + + C C PG G C+ + C C G C TA S Sbjct: 1010 CLDQPCHPTGTAACHSLANAFYCQCLPGHTGQWCEVEIDPCHSQPCFHGGTCEATAGSPL 1069 Query: 398 -YKCACPVTYTGKNC 439 + C CP + G C Sbjct: 1070 GFICHCPKGFEGPTC 1084 Score = 33.1 bits (72), Expect = 0.63 Identities = 18/51 (35%), Positives = 21/51 (41%), Gaps = 2/51 (3%) Frame = +2 Query: 233 PNLCLNNGVCQEA--LTEHGYVCLCAPGFGGNNCDRIGESCRPGLCGPGKC 379 P+ CL NG C E L G+ C C G C + G G G G C Sbjct: 1137 PSPCLYNGSCSETTGLGGPGFRCSCPHSSPGPRCQKPGAKGCEGRSGDGAC 1187 Score = 31.9 bits (69), Expect = 1.5 Identities = 23/86 (26%), Positives = 38/86 (44%), Gaps = 13/86 (15%) Frame = +2 Query: 224 TCAPNLCLNNGVCQEALTEHGYV--CLCAPGFGGNNCDRIGESCRPGLCGP-------GK 376 +C + C + G+C + + G+ C C G+GG +C + G CGP G Sbjct: 1090 SCGFHHCHHGGLCLPS-PKPGFPPRCACLSGYGGPDC--LTPPAPKG-CGPPSPCLYNGS 1145 Query: 377 CMNTAD----SYKCACPVTYTGKNCE 442 C T ++C+CP + G C+ Sbjct: 1146 CSETTGLGGPGFRCSCPHSSPGPRCQ 1171 >BX284686-1|CAM26209.1| 2003|Homo sapiens Notch homolog 4 (Drosophila) protein. Length = 2003 Score = 65.7 bits (153), Expect = 1e-10 Identities = 32/105 (30%), Positives = 48/105 (45%), Gaps = 1/105 (0%) Frame = +2 Query: 203 ENVQNCFTCAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLCGPGK-C 379 E+V C T P C N G CQ + + C+C G+GG +C+ + C C PG C Sbjct: 313 EDVDECETQGPPHCRNGGTCQNSAGS--FHCVCVSGWGGTSCEENLDDCIAATCAPGSTC 370 Query: 380 MNTADSYKCACPVTYTGKNCEVKQLIEYPAFTGSA*LAIKPPTST 514 ++ S+ C CP TG C ++ + G A + P T + Sbjct: 371 IDRVGSFSCLCPPGRTGLLCHLEDMCLSQPCHGDAQCSTNPLTGS 415 Score = 64.1 bits (149), Expect = 3e-10 Identities = 31/77 (40%), Positives = 40/77 (51%), Gaps = 3/77 (3%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESC--RPGLCGPG-KCMNTADS 397 C+ N C+N GVC + C C PGF G+ C+R C PG C G C NT S Sbjct: 160 CSANPCVNGGVCLATYPQ--IQCHCPPGFEGHACERDVNECFQDPGPCPKGTSCHNTLGS 217 Query: 398 YKCACPVTYTGKNCEVK 448 ++C CPV G CE++ Sbjct: 218 FQCLCPVGQEGPRCELR 234 Score = 61.3 bits (142), Expect = 2e-09 Identities = 28/74 (37%), Positives = 39/74 (52%), Gaps = 3/74 (4%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHG--YVCLCAPGFGGNNCDRIGESCRPGLC-GPGKCMNTADS 397 C P C N G CQ + ++CLC PGF G +C+ ++C C G C + D+ Sbjct: 238 CPPRGCSNGGTCQLMPEKDSTFHLCLCPPGFIGPDCEVNPDNCVSHQCQNGGTCQDGLDT 297 Query: 398 YKCACPVTYTGKNC 439 Y C CP T+TG +C Sbjct: 298 YTCLCPETWTGWDC 311 Score = 59.7 bits (138), Expect = 6e-09 Identities = 28/89 (31%), Positives = 44/89 (49%), Gaps = 3/89 (3%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLC-GPGKCMNTADSYK 403 CA CLN+ C + L +G+ C+C PGF G C+ + CR C G+C + ++ Sbjct: 517 CASAPCLNHADCHDLL--NGFQCICLPGFSGTRCEEDIDECRSSPCANGGQCQDQPGAFH 574 Query: 404 CACPVTYTGKNC--EVKQLIEYPAFTGSA 484 C C + G C EV + + P G++ Sbjct: 575 CKCLPGFEGPRCQTEVDECLSDPCPVGAS 603 Score = 59.7 bits (138), Expect = 6e-09 Identities = 30/90 (33%), Positives = 43/90 (47%), Gaps = 4/90 (4%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLC-GPGKCMNTADSYK 403 C C N C + GY+C CAPG+ G NC + ++C+ C G C + Sbjct: 934 CESRPCQNGATCMAQPS--GYLCQCAPGYDGQNCSKELDACQSQPCHNHGTCTPKPGGFH 991 Query: 404 CACPVTYTGKNCE--VKQLIEYPAF-TGSA 484 CACP + G CE V + ++ P TG+A Sbjct: 992 CACPPGFVGLRCEGDVDECLDQPCHPTGTA 1021 Score = 57.6 bits (133), Expect = 3e-08 Identities = 29/93 (31%), Positives = 38/93 (40%), Gaps = 8/93 (8%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLCGP------GKCMNT 388 C C + C +CLC PG+ G C + + C GP G C+NT Sbjct: 396 CLSQPCHGDAQCSTNPLTGSTLCLCQPGYSGPTCHQDLDECLMAQQGPSPCEHGGSCLNT 455 Query: 389 ADSYKCACPVTYTGKNCEV--KQLIEYPAFTGS 481 S+ C CP YTG CE + + P GS Sbjct: 456 PGSFNCLCPPGYTGSRCEADHNECLSQPCHPGS 488 Score = 54.0 bits (124), Expect = 3e-07 Identities = 25/74 (33%), Positives = 35/74 (47%), Gaps = 1/74 (1%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLCGPG-KCMNTADSYK 403 C + C N G CQ+ + C C PGF G C + C C G C++ ++ Sbjct: 555 CRSSPCANGGQCQDQ--PGAFHCKCLPGFEGPRCQTEVDECLSDPCPVGASCLDLPGAFF 612 Query: 404 CACPVTYTGKNCEV 445 C CP +TG+ CEV Sbjct: 613 CLCPSGFTGQLCEV 626 Score = 52.8 bits (121), Expect = 7e-07 Identities = 24/73 (32%), Positives = 36/73 (49%), Gaps = 1/73 (1%) Frame = +2 Query: 233 PNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLCGPGK-CMNTADSYKCA 409 P+ C + G C T + CLC PG+ G+ C+ C C PG C++ ++ C Sbjct: 443 PSPCEHGGSCLN--TPGSFNCLCPPGYTGSRCEADHNECLSQPCHPGSTCLDLLATFHCL 500 Query: 410 CPVTYTGKNCEVK 448 CP G+ CEV+ Sbjct: 501 CPPGLEGQLCEVE 513 Score = 52.8 bits (121), Expect = 7e-07 Identities = 26/87 (29%), Positives = 35/87 (40%), Gaps = 3/87 (3%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLC-GPGKCMNTADSYK 403 C C + G C + GY C C G+ G C +C G C G C + Y Sbjct: 695 CISAPCAHGGTCYPQPS--GYNCTCPTGYTGPTCSEEMTACHSGPCLNGGSCNPSPGGYY 752 Query: 404 CACPVTYTGKNCEVK--QLIEYPAFTG 478 C CP ++TG C+ + P F G Sbjct: 753 CTCPPSHTGPQCQTSTDYCVSAPCFNG 779 Score = 51.2 bits (117), Expect = 2e-06 Identities = 26/76 (34%), Positives = 35/76 (46%), Gaps = 4/76 (5%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCR---PGLC-GPGKCMNTAD 394 C + C N G CQ+ L Y CLC + G +C + C P C G C N+A Sbjct: 280 CVSHQCQNGGTCQDGLDT--YTCLCPETWTGWDCSEDVDECETQGPPHCRNGGTCQNSAG 337 Query: 395 SYKCACPVTYTGKNCE 442 S+ C C + G +CE Sbjct: 338 SFHCVCVSGWGGTSCE 353 Score = 51.2 bits (117), Expect = 2e-06 Identities = 24/75 (32%), Positives = 31/75 (41%), Gaps = 1/75 (1%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLC-GPGKCMNTADSYK 403 C CLN G C + GY C C P G C + C C G C+N ++ Sbjct: 733 CHSGPCLNGGSCNPS--PGGYYCTCPPSHTGPQCQTSTDYCVSAPCFNGGTCVNRPGTFS 790 Query: 404 CACPVTYTGKNCEVK 448 C C + + G CE K Sbjct: 791 CLCAMGFQGPRCEGK 805 Score = 50.4 bits (115), Expect = 4e-06 Identities = 25/69 (36%), Positives = 31/69 (44%), Gaps = 1/69 (1%) Frame = +2 Query: 236 NLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLCGPG-KCMNTADSYKCAC 412 +LC N G+C ++ Y C C PGF G+ C C C G CM Y C C Sbjct: 899 SLCHNGGLCVDS--GPSYFCHCPPGFQGSLCQDHVNPCESRPCQNGATCMAQPSGYLCQC 956 Query: 413 PVTYTGKNC 439 Y G+NC Sbjct: 957 APGYDGQNC 965 Score = 50.0 bits (114), Expect = 5e-06 Identities = 24/74 (32%), Positives = 33/74 (44%), Gaps = 2/74 (2%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCD-RIGESCRPGLC-GPGKCMNTADSY 400 C C N G C + CLCA GF G C+ ++ SC C C ++ Sbjct: 771 CVSAPCFNGGTCVNR--PGTFSCLCAMGFQGPRCEGKLRPSCADSPCRNRATCQDSPQGP 828 Query: 401 KCACPVTYTGKNCE 442 +C CP YTG +C+ Sbjct: 829 RCLCPTGYTGGSCQ 842 Score = 50.0 bits (114), Expect = 5e-06 Identities = 23/75 (30%), Positives = 35/75 (46%), Gaps = 1/75 (1%) Frame = +2 Query: 224 TCAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLCGPGK-CMNTADSY 400 +CA + C N CQ++ G CLC G+ G +C + + C C C+ T S+ Sbjct: 809 SCADSPCRNRATCQDS--PQGPRCLCPTGYTGGSCQTLMDLCAQKPCPRNSHCLQTGPSF 866 Query: 401 KCACPVTYTGKNCEV 445 C C +TG C + Sbjct: 867 HCLCLQGWTGPLCNL 881 Score = 49.2 bits (112), Expect = 9e-06 Identities = 28/86 (32%), Positives = 39/86 (45%), Gaps = 7/86 (8%) Frame = +2 Query: 212 QNCF----TCAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLCGP--- 370 QNC C C N+G C G+ C C PGF G C+ + C C P Sbjct: 963 QNCSKELDACQSQPCHNHGTCTPK--PGGFHCACPPGFVGLRCEGDVDECLDQPCHPTGT 1020 Query: 371 GKCMNTADSYKCACPVTYTGKNCEVK 448 C + A+++ C C +TG+ CEV+ Sbjct: 1021 AACHSLANAFYCQCLPGHTGQWCEVE 1046 Score = 46.8 bits (106), Expect = 5e-05 Identities = 22/76 (28%), Positives = 37/76 (48%), Gaps = 4/76 (5%) Frame = +2 Query: 287 YVCLCAPGFGGNNCD-RIGESCRPGLCGP-GKC-MNTADSYKCACPVTYTGKNCEVKQLI 457 ++C C PGF G C ++ + C P C G+C + + +C+C +TG+ C+++ Sbjct: 101 FLCTCLPGFTGERCQAKLEDPCPPSFCSKRGRCHIQASGRPQCSCMPGWTGEQCQLRDFC 160 Query: 458 E-YPAFTGSA*LAIKP 502 P G LA P Sbjct: 161 SANPCVNGGVCLATYP 176 Score = 41.5 bits (93), Expect = 0.002 Identities = 24/75 (32%), Positives = 30/75 (40%), Gaps = 4/75 (5%) Frame = +2 Query: 227 CAP---NLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLCGPG-KCMNTAD 394 CAP N ++G CQ + C+C G+ G C+ C C G C Sbjct: 658 CAPPEDNCTCHHGHCQRSS------CVCDVGWTGPECEAELGGCISAPCAHGGTCYPQPS 711 Query: 395 SYKCACPVTYTGKNC 439 Y C CP YTG C Sbjct: 712 GYNCTCPTGYTGPTC 726 Score = 40.7 bits (91), Expect = 0.003 Identities = 24/74 (32%), Positives = 34/74 (45%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLCGPGKCMNTADSYKC 406 CAPNLC +C++ + CLC G G C ++C C G C ++ C Sbjct: 629 CAPNLCQPKQICKDQKDKAN--CLCPDGSPG--CAPPEDNC---TCHHGHCQRSS----C 677 Query: 407 ACPVTYTGKNCEVK 448 C V +TG CE + Sbjct: 678 VCDVGWTGPECEAE 691 Score = 39.9 bits (89), Expect = 0.006 Identities = 27/87 (31%), Positives = 35/87 (40%), Gaps = 5/87 (5%) Frame = +2 Query: 200 KENVQNCFTCAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLCGPG-- 373 + +V CF P C C L + CLC G G C+ C P C G Sbjct: 192 ERDVNECFQ-DPGPCPKGTSCHNTLGS--FQCLCPVGQEGPRCELRAGPCPPRGCSNGGT 248 Query: 374 -KCMNTADS--YKCACPVTYTGKNCEV 445 + M DS + C CP + G +CEV Sbjct: 249 CQLMPEKDSTFHLCLCPPGFIGPDCEV 275 Score = 39.1 bits (87), Expect = 0.010 Identities = 19/73 (26%), Positives = 28/73 (38%), Gaps = 1/73 (1%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLC-GPGKCMNTADSYK 403 C C C + L + CLC PG G C+ C C C + + ++ Sbjct: 479 CLSQPCHPGSTCLDLLAT--FHCLCPPGLEGQLCEVETNECASAPCLNHADCHDLLNGFQ 536 Query: 404 CACPVTYTGKNCE 442 C C ++G CE Sbjct: 537 CICLPGFSGTRCE 549 Score = 38.7 bits (86), Expect = 0.013 Identities = 24/78 (30%), Positives = 31/78 (39%), Gaps = 7/78 (8%) Frame = +2 Query: 227 CAPNLCLNNGVCQE-ALTEHGYVCLCAPGFGGNNCDRIGESC------RPGLCGPGKCMN 385 C C + G C+ A + G++C C GF G C SC GLC P Sbjct: 1050 CHSQPCFHGGTCEATAGSPLGFICHCPKGFEGPTCSHRAPSCGFHHCHHGGLCLPSP--K 1107 Query: 386 TADSYKCACPVTYTGKNC 439 +CAC Y G +C Sbjct: 1108 PGFPPRCACLSGYGGPDC 1125 Score = 37.9 bits (84), Expect = 0.022 Identities = 27/87 (31%), Positives = 33/87 (37%), Gaps = 15/87 (17%) Frame = +2 Query: 233 PNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCD-----------RIGESCR---PGLCG- 367 P C N G C G C CAPGF G C + G SC+ P G Sbjct: 32 PEPCANGGTCLSLSLGQG-TCQCAPGFLGETCQFPDPCQNAQLCQNGGSCQALLPAPLGL 90 Query: 368 PGKCMNTADSYKCACPVTYTGKNCEVK 448 P S+ C C +TG+ C+ K Sbjct: 91 PSSPSPLTPSFLCTCLPGFTGERCQAK 117 Score = 37.9 bits (84), Expect = 0.022 Identities = 25/83 (30%), Positives = 35/83 (42%), Gaps = 11/83 (13%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPG----------LC-GPG 373 CA C N C + T + CLC G+ G C+ SC+ LC G Sbjct: 848 CAQKPCPRNSHCLQ--TGPSFHCLCLQGWTGPLCNLPLSSCQKAALSQGIDVSSLCHNGG 905 Query: 374 KCMNTADSYKCACPVTYTGKNCE 442 C+++ SY C CP + G C+ Sbjct: 906 LCVDSGPSYFCHCPPGFQGSLCQ 928 Score = 33.9 bits (74), Expect = 0.36 Identities = 21/75 (28%), Positives = 27/75 (36%), Gaps = 4/75 (5%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLC-GPGKCMNTADS-- 397 C C G + + C C PG G C+ + C C G C TA S Sbjct: 1010 CLDQPCHPTGTAACHSLANAFYCQCLPGHTGQWCEVEIDPCHSQPCFHGGTCEATAGSPL 1069 Query: 398 -YKCACPVTYTGKNC 439 + C CP + G C Sbjct: 1070 GFICHCPKGFEGPTC 1084 Score = 33.1 bits (72), Expect = 0.63 Identities = 18/51 (35%), Positives = 21/51 (41%), Gaps = 2/51 (3%) Frame = +2 Query: 233 PNLCLNNGVCQEA--LTEHGYVCLCAPGFGGNNCDRIGESCRPGLCGPGKC 379 P+ CL NG C E L G+ C C G C + G G G G C Sbjct: 1137 PSPCLYNGSCSETTGLGGPGFRCSCPHSSPGPRCQKPGAKGCEGRSGDGAC 1187 Score = 31.9 bits (69), Expect = 1.5 Identities = 23/86 (26%), Positives = 38/86 (44%), Gaps = 13/86 (15%) Frame = +2 Query: 224 TCAPNLCLNNGVCQEALTEHGYV--CLCAPGFGGNNCDRIGESCRPGLCGP-------GK 376 +C + C + G+C + + G+ C C G+GG +C + G CGP G Sbjct: 1090 SCGFHHCHHGGLCLPS-PKPGFPPRCACLSGYGGPDC--LTPPAPKG-CGPPSPCLYNGS 1145 Query: 377 CMNTAD----SYKCACPVTYTGKNCE 442 C T ++C+CP + G C+ Sbjct: 1146 CSETTGLGGPGFRCSCPHSSPGPRCQ 1171 >BC063815-1|AAH63815.1| 647|Homo sapiens NOTCH4 protein protein. Length = 647 Score = 65.7 bits (153), Expect = 1e-10 Identities = 32/105 (30%), Positives = 48/105 (45%), Gaps = 1/105 (0%) Frame = +2 Query: 203 ENVQNCFTCAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLCGPGK-C 379 E+V C T P C N G CQ + + C+C G+GG +C+ + C C PG C Sbjct: 313 EDVDECETQGPPHCRNGGTCQNSAGS--FHCVCVSGWGGTSCEENLDDCIAATCAPGSTC 370 Query: 380 MNTADSYKCACPVTYTGKNCEVKQLIEYPAFTGSA*LAIKPPTST 514 ++ S+ C CP TG C ++ + G A + P T + Sbjct: 371 IDRVGSFSCLCPPGRTGLLCHLEDMCLSQPCHGDAQCSTNPLTGS 415 Score = 64.1 bits (149), Expect = 3e-10 Identities = 31/77 (40%), Positives = 40/77 (51%), Gaps = 3/77 (3%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESC--RPGLCGPG-KCMNTADS 397 C+ N C+N GVC + C C PGF G+ C+R C PG C G C NT S Sbjct: 160 CSANPCVNGGVCLATYPQ--IQCHCPPGFEGHACERDVNECFQDPGPCPKGTSCHNTLGS 217 Query: 398 YKCACPVTYTGKNCEVK 448 ++C CPV G CE++ Sbjct: 218 FQCLCPVGQEGPRCELR 234 Score = 61.3 bits (142), Expect = 2e-09 Identities = 28/74 (37%), Positives = 39/74 (52%), Gaps = 3/74 (4%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHG--YVCLCAPGFGGNNCDRIGESCRPGLC-GPGKCMNTADS 397 C P C N G CQ + ++CLC PGF G +C+ ++C C G C + D+ Sbjct: 238 CPPRGCSNGGTCQLMPEKDSTFHLCLCPPGFIGPDCEVNPDNCVSHQCQNGGTCQDGLDT 297 Query: 398 YKCACPVTYTGKNC 439 Y C CP T+TG +C Sbjct: 298 YTCLCPETWTGWDC 311 Score = 59.7 bits (138), Expect = 6e-09 Identities = 28/89 (31%), Positives = 44/89 (49%), Gaps = 3/89 (3%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLC-GPGKCMNTADSYK 403 CA CLN+ C + L +G+ C+C PGF G C+ + CR C G+C + ++ Sbjct: 517 CASAPCLNHADCHDLL--NGFQCICLPGFSGTRCEEDIDECRSSPCANGGQCQDQPGAFH 574 Query: 404 CACPVTYTGKNC--EVKQLIEYPAFTGSA 484 C C + G C EV + + P G++ Sbjct: 575 CKCLPGFEGPRCQTEVDECLSDPCPVGAS 603 Score = 57.6 bits (133), Expect = 3e-08 Identities = 29/93 (31%), Positives = 38/93 (40%), Gaps = 8/93 (8%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLCGP------GKCMNT 388 C C + C +CLC PG+ G C + + C GP G C+NT Sbjct: 396 CLSQPCHGDAQCSTNPLTGSTLCLCQPGYSGPTCHQDLDECLMAQQGPSPCEHGGSCLNT 455 Query: 389 ADSYKCACPVTYTGKNCEV--KQLIEYPAFTGS 481 S+ C CP YTG CE + + P GS Sbjct: 456 PGSFNCLCPPGYTGSRCEADHNECLSQPCHPGS 488 Score = 52.8 bits (121), Expect = 7e-07 Identities = 24/73 (32%), Positives = 36/73 (49%), Gaps = 1/73 (1%) Frame = +2 Query: 233 PNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLCGPGK-CMNTADSYKCA 409 P+ C + G C T + CLC PG+ G+ C+ C C PG C++ ++ C Sbjct: 443 PSPCEHGGSCLN--TPGSFNCLCPPGYTGSRCEADHNECLSQPCHPGSTCLDLLATFHCL 500 Query: 410 CPVTYTGKNCEVK 448 CP G+ CEV+ Sbjct: 501 CPPGLEGQLCEVE 513 Score = 51.2 bits (117), Expect = 2e-06 Identities = 26/76 (34%), Positives = 35/76 (46%), Gaps = 4/76 (5%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCR---PGLC-GPGKCMNTAD 394 C + C N G CQ+ L Y CLC + G +C + C P C G C N+A Sbjct: 280 CVSHQCQNGGTCQDGLDT--YTCLCPETWTGWDCSEDVDECETQGPPHCRNGGTCQNSAG 337 Query: 395 SYKCACPVTYTGKNCE 442 S+ C C + G +CE Sbjct: 338 SFHCVCVSGWGGTSCE 353 Score = 50.0 bits (114), Expect = 5e-06 Identities = 26/81 (32%), Positives = 37/81 (45%), Gaps = 2/81 (2%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLCGPG-KCMNTADSYK 403 C + C N G CQ+ + C C PGF G C + C C G C++ ++ Sbjct: 555 CRSSPCANGGQCQDQ--PGAFHCKCLPGFEGPRCQTEVDECLSDPCPVGASCLDLPGAFF 612 Query: 404 CACPVTYTG-KNCEVKQLIEY 463 C CP +TG + K+L EY Sbjct: 613 CLCPSGFTGSQGRHWKELAEY 633 Score = 46.8 bits (106), Expect = 5e-05 Identities = 22/76 (28%), Positives = 37/76 (48%), Gaps = 4/76 (5%) Frame = +2 Query: 287 YVCLCAPGFGGNNCD-RIGESCRPGLCGP-GKC-MNTADSYKCACPVTYTGKNCEVKQLI 457 ++C C PGF G C ++ + C P C G+C + + +C+C +TG+ C+++ Sbjct: 101 FLCTCLPGFTGERCQAKLEDPCPPSFCSKRGRCHIQASGRPQCSCMPGWTGEQCQLRDFC 160 Query: 458 E-YPAFTGSA*LAIKP 502 P G LA P Sbjct: 161 SANPCVNGGVCLATYP 176 Score = 39.9 bits (89), Expect = 0.006 Identities = 27/87 (31%), Positives = 35/87 (40%), Gaps = 5/87 (5%) Frame = +2 Query: 200 KENVQNCFTCAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLCGPG-- 373 + +V CF P C C L + CLC G G C+ C P C G Sbjct: 192 ERDVNECFQ-DPGPCPKGTSCHNTLGS--FQCLCPVGQEGPRCELRAGPCPPRGCSNGGT 248 Query: 374 -KCMNTADS--YKCACPVTYTGKNCEV 445 + M DS + C CP + G +CEV Sbjct: 249 CQLMPEKDSTFHLCLCPPGFIGPDCEV 275 Score = 39.1 bits (87), Expect = 0.010 Identities = 19/73 (26%), Positives = 28/73 (38%), Gaps = 1/73 (1%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLC-GPGKCMNTADSYK 403 C C C + L + CLC PG G C+ C C C + + ++ Sbjct: 479 CLSQPCHPGSTCLDLLAT--FHCLCPPGLEGQLCEVETNECASAPCLNHADCHDLLNGFQ 536 Query: 404 CACPVTYTGKNCE 442 C C ++G CE Sbjct: 537 CICLPGFSGTRCE 549 Score = 37.9 bits (84), Expect = 0.022 Identities = 27/87 (31%), Positives = 33/87 (37%), Gaps = 15/87 (17%) Frame = +2 Query: 233 PNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCD-----------RIGESCR---PGLCG- 367 P C N G C G C CAPGF G C + G SC+ P G Sbjct: 32 PEPCANGGTCLSLSLGQG-TCQCAPGFLGETCQFPDPCQNAQLCQNGGSCQALLPAPLGL 90 Query: 368 PGKCMNTADSYKCACPVTYTGKNCEVK 448 P S+ C C +TG+ C+ K Sbjct: 91 PSSPSPLTPSFLCTCLPGFTGERCQAK 117 >AL845509-1|CAI18564.1| 2003|Homo sapiens Notch homolog 4 (Drosophila) protein. Length = 2003 Score = 65.7 bits (153), Expect = 1e-10 Identities = 32/105 (30%), Positives = 48/105 (45%), Gaps = 1/105 (0%) Frame = +2 Query: 203 ENVQNCFTCAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLCGPGK-C 379 E+V C T P C N G CQ + + C+C G+GG +C+ + C C PG C Sbjct: 313 EDVDECETQGPPHCRNGGTCQNSAGS--FHCVCVSGWGGTSCEENLDDCIAATCAPGSTC 370 Query: 380 MNTADSYKCACPVTYTGKNCEVKQLIEYPAFTGSA*LAIKPPTST 514 ++ S+ C CP TG C ++ + G A + P T + Sbjct: 371 IDRVGSFSCLCPPGRTGLLCHLEDMCLSQPCHGDAQCSTNPLTGS 415 Score = 64.1 bits (149), Expect = 3e-10 Identities = 31/77 (40%), Positives = 40/77 (51%), Gaps = 3/77 (3%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESC--RPGLCGPG-KCMNTADS 397 C+ N C+N GVC + C C PGF G+ C+R C PG C G C NT S Sbjct: 160 CSANPCVNGGVCLATYPQ--IQCHCPPGFEGHACERDVNECFQDPGPCPKGTSCHNTLGS 217 Query: 398 YKCACPVTYTGKNCEVK 448 ++C CPV G CE++ Sbjct: 218 FQCLCPVGQEGPRCELR 234 Score = 61.3 bits (142), Expect = 2e-09 Identities = 28/74 (37%), Positives = 39/74 (52%), Gaps = 3/74 (4%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHG--YVCLCAPGFGGNNCDRIGESCRPGLC-GPGKCMNTADS 397 C P C N G CQ + ++CLC PGF G +C+ ++C C G C + D+ Sbjct: 238 CPPRGCSNGGTCQLMPEKDSTFHLCLCPPGFIGPDCEVNPDNCVSHQCQNGGTCQDGLDT 297 Query: 398 YKCACPVTYTGKNC 439 Y C CP T+TG +C Sbjct: 298 YTCLCPETWTGWDC 311 Score = 59.7 bits (138), Expect = 6e-09 Identities = 28/89 (31%), Positives = 44/89 (49%), Gaps = 3/89 (3%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLC-GPGKCMNTADSYK 403 CA CLN+ C + L +G+ C+C PGF G C+ + CR C G+C + ++ Sbjct: 517 CASAPCLNHADCHDLL--NGFQCICLPGFSGTRCEEDIDECRSSPCANGGQCQDQPGAFH 574 Query: 404 CACPVTYTGKNC--EVKQLIEYPAFTGSA 484 C C + G C EV + + P G++ Sbjct: 575 CKCLPGFEGPRCQTEVDECLSDPCPVGAS 603 Score = 59.7 bits (138), Expect = 6e-09 Identities = 30/90 (33%), Positives = 43/90 (47%), Gaps = 4/90 (4%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLC-GPGKCMNTADSYK 403 C C N C + GY+C CAPG+ G NC + ++C+ C G C + Sbjct: 934 CESRPCQNGATCMAQPS--GYLCQCAPGYDGQNCSKELDACQSQPCHNHGTCTPKPGGFH 991 Query: 404 CACPVTYTGKNCE--VKQLIEYPAF-TGSA 484 CACP + G CE V + ++ P TG+A Sbjct: 992 CACPPGFVGLRCEGDVDECLDQPCHPTGTA 1021 Score = 57.6 bits (133), Expect = 3e-08 Identities = 29/93 (31%), Positives = 38/93 (40%), Gaps = 8/93 (8%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLCGP------GKCMNT 388 C C + C +CLC PG+ G C + + C GP G C+NT Sbjct: 396 CLSQPCHGDAQCSTNPLTGSTLCLCQPGYSGPTCHQDLDECLMAQQGPSPCEHGGSCLNT 455 Query: 389 ADSYKCACPVTYTGKNCEV--KQLIEYPAFTGS 481 S+ C CP YTG CE + + P GS Sbjct: 456 PGSFNCLCPPGYTGSRCEADHNECLSQPCHPGS 488 Score = 54.0 bits (124), Expect = 3e-07 Identities = 25/74 (33%), Positives = 35/74 (47%), Gaps = 1/74 (1%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLCGPG-KCMNTADSYK 403 C + C N G CQ+ + C C PGF G C + C C G C++ ++ Sbjct: 555 CRSSPCANGGQCQDQ--PGAFHCKCLPGFEGPRCQTEVDECLSDPCPVGASCLDLPGAFF 612 Query: 404 CACPVTYTGKNCEV 445 C CP +TG+ CEV Sbjct: 613 CLCPSGFTGQLCEV 626 Score = 52.8 bits (121), Expect = 7e-07 Identities = 24/73 (32%), Positives = 36/73 (49%), Gaps = 1/73 (1%) Frame = +2 Query: 233 PNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLCGPGK-CMNTADSYKCA 409 P+ C + G C T + CLC PG+ G+ C+ C C PG C++ ++ C Sbjct: 443 PSPCEHGGSCLN--TPGSFNCLCPPGYTGSRCEADHNECLSQPCHPGSTCLDLLATFHCL 500 Query: 410 CPVTYTGKNCEVK 448 CP G+ CEV+ Sbjct: 501 CPPGLEGQLCEVE 513 Score = 52.8 bits (121), Expect = 7e-07 Identities = 26/87 (29%), Positives = 35/87 (40%), Gaps = 3/87 (3%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLC-GPGKCMNTADSYK 403 C C + G C + GY C C G+ G C +C G C G C + Y Sbjct: 695 CISAPCAHGGTCYPQPS--GYNCTCPTGYTGPTCSEEMTACHSGPCLNGGSCNPSPGGYY 752 Query: 404 CACPVTYTGKNCEVK--QLIEYPAFTG 478 C CP ++TG C+ + P F G Sbjct: 753 CTCPPSHTGPQCQTSTDYCVSAPCFNG 779 Score = 51.2 bits (117), Expect = 2e-06 Identities = 26/76 (34%), Positives = 35/76 (46%), Gaps = 4/76 (5%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCR---PGLC-GPGKCMNTAD 394 C + C N G CQ+ L Y CLC + G +C + C P C G C N+A Sbjct: 280 CVSHQCQNGGTCQDGLDT--YTCLCPETWTGWDCSEDVDECETQGPPHCRNGGTCQNSAG 337 Query: 395 SYKCACPVTYTGKNCE 442 S+ C C + G +CE Sbjct: 338 SFHCVCVSGWGGTSCE 353 Score = 51.2 bits (117), Expect = 2e-06 Identities = 24/75 (32%), Positives = 31/75 (41%), Gaps = 1/75 (1%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLC-GPGKCMNTADSYK 403 C CLN G C + GY C C P G C + C C G C+N ++ Sbjct: 733 CHSGPCLNGGSCNPS--PGGYYCTCPPSHTGPQCQTSTDYCVSAPCFNGGTCVNRPGTFS 790 Query: 404 CACPVTYTGKNCEVK 448 C C + + G CE K Sbjct: 791 CLCAMGFQGPRCEGK 805 Score = 50.8 bits (116), Expect = 3e-06 Identities = 24/74 (32%), Positives = 33/74 (44%), Gaps = 2/74 (2%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCD-RIGESCRPGLC-GPGKCMNTADSY 400 C C N G C + CLCA GF G C+ ++ SC C C ++ Sbjct: 771 CVSAPCFNGGTCVNR--PGTFSCLCAMGFQGPRCEGKLRPSCADSPCRNRATCQDSPQGP 828 Query: 401 KCACPVTYTGKNCE 442 +C CP YTG +C+ Sbjct: 829 RCLCPTVYTGGSCQ 842 Score = 50.4 bits (115), Expect = 4e-06 Identities = 25/69 (36%), Positives = 31/69 (44%), Gaps = 1/69 (1%) Frame = +2 Query: 236 NLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLCGPG-KCMNTADSYKCAC 412 +LC N G+C ++ Y C C PGF G+ C C C G CM Y C C Sbjct: 899 SLCHNGGLCVDS--GPSYFCHCPPGFQGSLCQDHVNPCESRPCQNGATCMAQPSGYLCQC 956 Query: 413 PVTYTGKNC 439 Y G+NC Sbjct: 957 APGYDGQNC 965 Score = 49.2 bits (112), Expect = 9e-06 Identities = 28/86 (32%), Positives = 39/86 (45%), Gaps = 7/86 (8%) Frame = +2 Query: 212 QNCF----TCAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLCGP--- 370 QNC C C N+G C G+ C C PGF G C+ + C C P Sbjct: 963 QNCSKELDACQSQPCHNHGTCTPK--PGGFHCACPPGFVGLRCEGDVDECLDQPCHPTGT 1020 Query: 371 GKCMNTADSYKCACPVTYTGKNCEVK 448 C + A+++ C C +TG+ CEV+ Sbjct: 1021 AACHSLANAFYCQCLPGHTGQWCEVE 1046 Score = 46.8 bits (106), Expect = 5e-05 Identities = 22/76 (28%), Positives = 37/76 (48%), Gaps = 4/76 (5%) Frame = +2 Query: 287 YVCLCAPGFGGNNCD-RIGESCRPGLCGP-GKC-MNTADSYKCACPVTYTGKNCEVKQLI 457 ++C C PGF G C ++ + C P C G+C + + +C+C +TG+ C+++ Sbjct: 101 FLCTCLPGFTGERCQAKLEDPCPPSFCSKRGRCHIQASGRPQCSCMPGWTGEQCQLRDFC 160 Query: 458 E-YPAFTGSA*LAIKP 502 P G LA P Sbjct: 161 SANPCVNGGVCLATYP 176 Score = 46.4 bits (105), Expect = 6e-05 Identities = 22/75 (29%), Positives = 34/75 (45%), Gaps = 1/75 (1%) Frame = +2 Query: 224 TCAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLCGPGK-CMNTADSY 400 +CA + C N CQ++ G CLC + G +C + + C C C+ T S+ Sbjct: 809 SCADSPCRNRATCQDS--PQGPRCLCPTVYTGGSCQTLMDLCAQKPCPRNSHCLQTGPSF 866 Query: 401 KCACPVTYTGKNCEV 445 C C +TG C + Sbjct: 867 HCLCLQGWTGPLCNL 881 Score = 41.5 bits (93), Expect = 0.002 Identities = 24/75 (32%), Positives = 30/75 (40%), Gaps = 4/75 (5%) Frame = +2 Query: 227 CAP---NLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLCGPG-KCMNTAD 394 CAP N ++G CQ + C+C G+ G C+ C C G C Sbjct: 658 CAPPEDNCTCHHGHCQRSS------CVCDVGWTGPECEAELGGCISAPCAHGGTCYPQPS 711 Query: 395 SYKCACPVTYTGKNC 439 Y C CP YTG C Sbjct: 712 GYNCTCPTGYTGPTC 726 Score = 40.7 bits (91), Expect = 0.003 Identities = 24/74 (32%), Positives = 34/74 (45%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLCGPGKCMNTADSYKC 406 CAPNLC +C++ + CLC G G C ++C C G C ++ C Sbjct: 629 CAPNLCQPKQICKDQKDKAN--CLCPDGSPG--CAPPEDNC---TCHHGHCQRSS----C 677 Query: 407 ACPVTYTGKNCEVK 448 C V +TG CE + Sbjct: 678 VCDVGWTGPECEAE 691 Score = 39.9 bits (89), Expect = 0.006 Identities = 27/87 (31%), Positives = 35/87 (40%), Gaps = 5/87 (5%) Frame = +2 Query: 200 KENVQNCFTCAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLCGPG-- 373 + +V CF P C C L + CLC G G C+ C P C G Sbjct: 192 ERDVNECFQ-DPGPCPKGTSCHNTLGS--FQCLCPVGQEGPRCELRAGPCPPRGCSNGGT 248 Query: 374 -KCMNTADS--YKCACPVTYTGKNCEV 445 + M DS + C CP + G +CEV Sbjct: 249 CQLMPEKDSTFHLCLCPPGFIGPDCEV 275 Score = 39.1 bits (87), Expect = 0.010 Identities = 19/73 (26%), Positives = 28/73 (38%), Gaps = 1/73 (1%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLC-GPGKCMNTADSYK 403 C C C + L + CLC PG G C+ C C C + + ++ Sbjct: 479 CLSQPCHPGSTCLDLLAT--FHCLCPPGLEGQLCEVETNECASAPCLNHADCHDLLNGFQ 536 Query: 404 CACPVTYTGKNCE 442 C C ++G CE Sbjct: 537 CICLPGFSGTRCE 549 Score = 38.7 bits (86), Expect = 0.013 Identities = 24/78 (30%), Positives = 31/78 (39%), Gaps = 7/78 (8%) Frame = +2 Query: 227 CAPNLCLNNGVCQE-ALTEHGYVCLCAPGFGGNNCDRIGESC------RPGLCGPGKCMN 385 C C + G C+ A + G++C C GF G C SC GLC P Sbjct: 1050 CHSQPCFHGGTCEATAGSPLGFICHCPKGFEGPTCSHRAPSCGFHHCHHGGLCLPSP--K 1107 Query: 386 TADSYKCACPVTYTGKNC 439 +CAC Y G +C Sbjct: 1108 PGFPPRCACLSGYGGPDC 1125 Score = 37.9 bits (84), Expect = 0.022 Identities = 27/87 (31%), Positives = 33/87 (37%), Gaps = 15/87 (17%) Frame = +2 Query: 233 PNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCD-----------RIGESCR---PGLCG- 367 P C N G C G C CAPGF G C + G SC+ P G Sbjct: 32 PEPCANGGTCLSLSLGQG-TCQCAPGFLGETCQFPDPCQNAQLCQNGGSCQALLPAPLGL 90 Query: 368 PGKCMNTADSYKCACPVTYTGKNCEVK 448 P S+ C C +TG+ C+ K Sbjct: 91 PSSPSPLTPSFLCTCLPGFTGERCQAK 117 Score = 37.9 bits (84), Expect = 0.022 Identities = 25/83 (30%), Positives = 35/83 (42%), Gaps = 11/83 (13%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPG----------LC-GPG 373 CA C N C + T + CLC G+ G C+ SC+ LC G Sbjct: 848 CAQKPCPRNSHCLQ--TGPSFHCLCLQGWTGPLCNLPLSSCQKAALSQGIDVSSLCHNGG 905 Query: 374 KCMNTADSYKCACPVTYTGKNCE 442 C+++ SY C CP + G C+ Sbjct: 906 LCVDSGPSYFCHCPPGFQGSLCQ 928 Score = 33.9 bits (74), Expect = 0.36 Identities = 21/75 (28%), Positives = 27/75 (36%), Gaps = 4/75 (5%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLC-GPGKCMNTADS-- 397 C C G + + C C PG G C+ + C C G C TA S Sbjct: 1010 CLDQPCHPTGTAACHSLANAFYCQCLPGHTGQWCEVEIDPCHSQPCFHGGTCEATAGSPL 1069 Query: 398 -YKCACPVTYTGKNC 439 + C CP + G C Sbjct: 1070 GFICHCPKGFEGPTC 1084 Score = 33.1 bits (72), Expect = 0.63 Identities = 18/51 (35%), Positives = 21/51 (41%), Gaps = 2/51 (3%) Frame = +2 Query: 233 PNLCLNNGVCQEA--LTEHGYVCLCAPGFGGNNCDRIGESCRPGLCGPGKC 379 P+ CL NG C E L G+ C C G C + G G G G C Sbjct: 1137 PSPCLYNGSCSETTGLGGPGFRCSCPHSSPGPRCQKPGAKGCEGRSGDGAC 1187 Score = 31.9 bits (69), Expect = 1.5 Identities = 23/86 (26%), Positives = 38/86 (44%), Gaps = 13/86 (15%) Frame = +2 Query: 224 TCAPNLCLNNGVCQEALTEHGYV--CLCAPGFGGNNCDRIGESCRPGLCGP-------GK 376 +C + C + G+C + + G+ C C G+GG +C + G CGP G Sbjct: 1090 SCGFHHCHHGGLCLPS-PKPGFPPRCACLSGYGGPDC--LTPPAPKG-CGPPSPCLYNGS 1145 Query: 377 CMNTAD----SYKCACPVTYTGKNCE 442 C T ++C+CP + G C+ Sbjct: 1146 CSETTGLGGPGFRCSCPHSSPGPRCQ 1171 >AL845464-12|CAI41803.1| 2003|Homo sapiens Notch homolog 4 (Drosophila) protein. Length = 2003 Score = 65.7 bits (153), Expect = 1e-10 Identities = 32/105 (30%), Positives = 48/105 (45%), Gaps = 1/105 (0%) Frame = +2 Query: 203 ENVQNCFTCAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLCGPGK-C 379 E+V C T P C N G CQ + + C+C G+GG +C+ + C C PG C Sbjct: 313 EDVDECETQGPPHCRNGGTCQNSAGS--FHCVCVSGWGGTSCEENLDDCIAATCAPGSTC 370 Query: 380 MNTADSYKCACPVTYTGKNCEVKQLIEYPAFTGSA*LAIKPPTST 514 ++ S+ C CP TG C ++ + G A + P T + Sbjct: 371 IDRVGSFSCLCPPGRTGLLCHLEDMCLSQPCHGDAQCSTNPLTGS 415 Score = 64.1 bits (149), Expect = 3e-10 Identities = 31/77 (40%), Positives = 40/77 (51%), Gaps = 3/77 (3%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESC--RPGLCGPG-KCMNTADS 397 C+ N C+N GVC + C C PGF G+ C+R C PG C G C NT S Sbjct: 160 CSANPCVNGGVCLATYPQ--IQCHCPPGFEGHACERDVNECFQDPGPCPKGTSCHNTLGS 217 Query: 398 YKCACPVTYTGKNCEVK 448 ++C CPV G CE++ Sbjct: 218 FQCLCPVGQEGPRCELR 234 Score = 61.3 bits (142), Expect = 2e-09 Identities = 28/74 (37%), Positives = 39/74 (52%), Gaps = 3/74 (4%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHG--YVCLCAPGFGGNNCDRIGESCRPGLC-GPGKCMNTADS 397 C P C N G CQ + ++CLC PGF G +C+ ++C C G C + D+ Sbjct: 238 CPPRGCSNGGTCQLMPEKDSTFHLCLCPPGFIGPDCEVNPDNCVSHQCQNGGTCQDGLDT 297 Query: 398 YKCACPVTYTGKNC 439 Y C CP T+TG +C Sbjct: 298 YTCLCPETWTGWDC 311 Score = 59.7 bits (138), Expect = 6e-09 Identities = 28/89 (31%), Positives = 44/89 (49%), Gaps = 3/89 (3%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLC-GPGKCMNTADSYK 403 CA CLN+ C + L +G+ C+C PGF G C+ + CR C G+C + ++ Sbjct: 517 CASAPCLNHADCHDLL--NGFQCICLPGFSGTRCEEDIDECRSSPCANGGQCQDQPGAFH 574 Query: 404 CACPVTYTGKNC--EVKQLIEYPAFTGSA 484 C C + G C EV + + P G++ Sbjct: 575 CKCLPGFEGPRCQTEVDECLSDPCPVGAS 603 Score = 59.7 bits (138), Expect = 6e-09 Identities = 30/90 (33%), Positives = 43/90 (47%), Gaps = 4/90 (4%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLC-GPGKCMNTADSYK 403 C C N C + GY+C CAPG+ G NC + ++C+ C G C + Sbjct: 934 CESRPCQNGATCMAQPS--GYLCQCAPGYDGQNCSKELDACQSQPCHNHGTCTPKPGGFH 991 Query: 404 CACPVTYTGKNCE--VKQLIEYPAF-TGSA 484 CACP + G CE V + ++ P TG+A Sbjct: 992 CACPPGFVGLRCEGDVDECLDQPCHPTGTA 1021 Score = 57.6 bits (133), Expect = 3e-08 Identities = 29/93 (31%), Positives = 38/93 (40%), Gaps = 8/93 (8%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLCGP------GKCMNT 388 C C + C +CLC PG+ G C + + C GP G C+NT Sbjct: 396 CLSQPCHGDAQCSTNPLTGSTLCLCQPGYSGPTCHQDLDECLMAQQGPSPCEHGGSCLNT 455 Query: 389 ADSYKCACPVTYTGKNCEV--KQLIEYPAFTGS 481 S+ C CP YTG CE + + P GS Sbjct: 456 PGSFNCLCPPGYTGSRCEADHNECLSQPCHPGS 488 Score = 54.0 bits (124), Expect = 3e-07 Identities = 25/74 (33%), Positives = 35/74 (47%), Gaps = 1/74 (1%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLCGPG-KCMNTADSYK 403 C + C N G CQ+ + C C PGF G C + C C G C++ ++ Sbjct: 555 CRSSPCANGGQCQDQ--PGAFHCKCLPGFEGPRCQTEVDECLSDPCPVGASCLDLPGAFF 612 Query: 404 CACPVTYTGKNCEV 445 C CP +TG+ CEV Sbjct: 613 CLCPSGFTGQLCEV 626 Score = 52.8 bits (121), Expect = 7e-07 Identities = 24/73 (32%), Positives = 36/73 (49%), Gaps = 1/73 (1%) Frame = +2 Query: 233 PNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLCGPGK-CMNTADSYKCA 409 P+ C + G C T + CLC PG+ G+ C+ C C PG C++ ++ C Sbjct: 443 PSPCEHGGSCLN--TPGSFNCLCPPGYTGSRCEADHNECLSQPCHPGSTCLDLLATFHCL 500 Query: 410 CPVTYTGKNCEVK 448 CP G+ CEV+ Sbjct: 501 CPPGLEGQLCEVE 513 Score = 52.8 bits (121), Expect = 7e-07 Identities = 26/87 (29%), Positives = 35/87 (40%), Gaps = 3/87 (3%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLC-GPGKCMNTADSYK 403 C C + G C + GY C C G+ G C +C G C G C + Y Sbjct: 695 CISAPCAHGGTCYPQPS--GYNCTCPTGYTGPTCSEEMTACHSGPCLNGGSCNPSPGGYY 752 Query: 404 CACPVTYTGKNCEVK--QLIEYPAFTG 478 C CP ++TG C+ + P F G Sbjct: 753 CTCPPSHTGPQCQTSTDYCVSAPCFNG 779 Score = 51.2 bits (117), Expect = 2e-06 Identities = 26/76 (34%), Positives = 35/76 (46%), Gaps = 4/76 (5%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCR---PGLC-GPGKCMNTAD 394 C + C N G CQ+ L Y CLC + G +C + C P C G C N+A Sbjct: 280 CVSHQCQNGGTCQDGLDT--YTCLCPETWTGWDCSEDVDECETQGPPHCRNGGTCQNSAG 337 Query: 395 SYKCACPVTYTGKNCE 442 S+ C C + G +CE Sbjct: 338 SFHCVCVSGWGGTSCE 353 Score = 51.2 bits (117), Expect = 2e-06 Identities = 24/75 (32%), Positives = 31/75 (41%), Gaps = 1/75 (1%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLC-GPGKCMNTADSYK 403 C CLN G C + GY C C P G C + C C G C+N ++ Sbjct: 733 CHSGPCLNGGSCNPS--PGGYYCTCPPSHTGPQCQTSTDYCVSAPCFNGGTCVNRPGTFS 790 Query: 404 CACPVTYTGKNCEVK 448 C C + + G CE K Sbjct: 791 CLCAMGFQGPRCEGK 805 Score = 50.8 bits (116), Expect = 3e-06 Identities = 24/74 (32%), Positives = 33/74 (44%), Gaps = 2/74 (2%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCD-RIGESCRPGLC-GPGKCMNTADSY 400 C C N G C + CLCA GF G C+ ++ SC C C ++ Sbjct: 771 CVSAPCFNGGTCVNR--PGTFSCLCAMGFQGPRCEGKLRPSCADSPCRNRATCQDSPQGP 828 Query: 401 KCACPVTYTGKNCE 442 +C CP YTG +C+ Sbjct: 829 RCLCPTVYTGGSCQ 842 Score = 50.4 bits (115), Expect = 4e-06 Identities = 25/69 (36%), Positives = 31/69 (44%), Gaps = 1/69 (1%) Frame = +2 Query: 236 NLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLCGPG-KCMNTADSYKCAC 412 +LC N G+C ++ Y C C PGF G+ C C C G CM Y C C Sbjct: 899 SLCHNGGLCVDS--GPSYFCHCPPGFQGSLCQDHVNPCESRPCQNGATCMAQPSGYLCQC 956 Query: 413 PVTYTGKNC 439 Y G+NC Sbjct: 957 APGYDGQNC 965 Score = 49.2 bits (112), Expect = 9e-06 Identities = 28/86 (32%), Positives = 39/86 (45%), Gaps = 7/86 (8%) Frame = +2 Query: 212 QNCF----TCAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLCGP--- 370 QNC C C N+G C G+ C C PGF G C+ + C C P Sbjct: 963 QNCSKELDACQSQPCHNHGTCTPK--PGGFHCACPPGFVGLRCEGDVDECLDQPCHPTGT 1020 Query: 371 GKCMNTADSYKCACPVTYTGKNCEVK 448 C + A+++ C C +TG+ CEV+ Sbjct: 1021 AACHSLANAFYCQCLPGHTGQWCEVE 1046 Score = 46.8 bits (106), Expect = 5e-05 Identities = 22/76 (28%), Positives = 37/76 (48%), Gaps = 4/76 (5%) Frame = +2 Query: 287 YVCLCAPGFGGNNCD-RIGESCRPGLCGP-GKC-MNTADSYKCACPVTYTGKNCEVKQLI 457 ++C C PGF G C ++ + C P C G+C + + +C+C +TG+ C+++ Sbjct: 101 FLCTCLPGFTGERCQAKLEDPCPPSFCSKRGRCHIQASGRPQCSCMPGWTGEQCQLRDFC 160 Query: 458 E-YPAFTGSA*LAIKP 502 P G LA P Sbjct: 161 SANPCVNGGVCLATYP 176 Score = 46.4 bits (105), Expect = 6e-05 Identities = 22/75 (29%), Positives = 34/75 (45%), Gaps = 1/75 (1%) Frame = +2 Query: 224 TCAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLCGPGK-CMNTADSY 400 +CA + C N CQ++ G CLC + G +C + + C C C+ T S+ Sbjct: 809 SCADSPCRNRATCQDS--PQGPRCLCPTVYTGGSCQTLMDLCAQKPCPRNSHCLQTGPSF 866 Query: 401 KCACPVTYTGKNCEV 445 C C +TG C + Sbjct: 867 HCLCLQGWTGPLCNL 881 Score = 41.5 bits (93), Expect = 0.002 Identities = 24/75 (32%), Positives = 30/75 (40%), Gaps = 4/75 (5%) Frame = +2 Query: 227 CAP---NLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLCGPG-KCMNTAD 394 CAP N ++G CQ + C+C G+ G C+ C C G C Sbjct: 658 CAPPEDNCTCHHGHCQRSS------CVCDVGWTGPECEAELGGCISAPCAHGGTCYPQPS 711 Query: 395 SYKCACPVTYTGKNC 439 Y C CP YTG C Sbjct: 712 GYNCTCPTGYTGPTC 726 Score = 40.7 bits (91), Expect = 0.003 Identities = 24/74 (32%), Positives = 34/74 (45%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLCGPGKCMNTADSYKC 406 CAPNLC +C++ + CLC G G C ++C C G C ++ C Sbjct: 629 CAPNLCQPKQICKDQKDKAN--CLCPDGSPG--CAPPEDNC---TCHHGHCQRSS----C 677 Query: 407 ACPVTYTGKNCEVK 448 C V +TG CE + Sbjct: 678 VCDVGWTGPECEAE 691 Score = 39.9 bits (89), Expect = 0.006 Identities = 27/87 (31%), Positives = 35/87 (40%), Gaps = 5/87 (5%) Frame = +2 Query: 200 KENVQNCFTCAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLCGPG-- 373 + +V CF P C C L + CLC G G C+ C P C G Sbjct: 192 ERDVNECFQ-DPGPCPKGTSCHNTLGS--FQCLCPVGQEGPRCELRAGPCPPRGCSNGGT 248 Query: 374 -KCMNTADS--YKCACPVTYTGKNCEV 445 + M DS + C CP + G +CEV Sbjct: 249 CQLMPEKDSTFHLCLCPPGFIGPDCEV 275 Score = 39.1 bits (87), Expect = 0.010 Identities = 19/73 (26%), Positives = 28/73 (38%), Gaps = 1/73 (1%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLC-GPGKCMNTADSYK 403 C C C + L + CLC PG G C+ C C C + + ++ Sbjct: 479 CLSQPCHPGSTCLDLLAT--FHCLCPPGLEGQLCEVETNECASAPCLNHADCHDLLNGFQ 536 Query: 404 CACPVTYTGKNCE 442 C C ++G CE Sbjct: 537 CICLPGFSGTRCE 549 Score = 38.7 bits (86), Expect = 0.013 Identities = 24/78 (30%), Positives = 31/78 (39%), Gaps = 7/78 (8%) Frame = +2 Query: 227 CAPNLCLNNGVCQE-ALTEHGYVCLCAPGFGGNNCDRIGESC------RPGLCGPGKCMN 385 C C + G C+ A + G++C C GF G C SC GLC P Sbjct: 1050 CHSQPCFHGGTCEATAGSPLGFICHCPKGFEGPTCSHRAPSCGFHHCHHGGLCLPSP--K 1107 Query: 386 TADSYKCACPVTYTGKNC 439 +CAC Y G +C Sbjct: 1108 PGFPPRCACLSGYGGPDC 1125 Score = 37.9 bits (84), Expect = 0.022 Identities = 27/87 (31%), Positives = 33/87 (37%), Gaps = 15/87 (17%) Frame = +2 Query: 233 PNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCD-----------RIGESCR---PGLCG- 367 P C N G C G C CAPGF G C + G SC+ P G Sbjct: 32 PEPCANGGTCLSLSLGQG-TCQCAPGFLGETCQFPDPCQNAQLCQNGGSCQALLPAPLGL 90 Query: 368 PGKCMNTADSYKCACPVTYTGKNCEVK 448 P S+ C C +TG+ C+ K Sbjct: 91 PSSPSPLTPSFLCTCLPGFTGERCQAK 117 Score = 37.9 bits (84), Expect = 0.022 Identities = 25/83 (30%), Positives = 35/83 (42%), Gaps = 11/83 (13%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPG----------LC-GPG 373 CA C N C + T + CLC G+ G C+ SC+ LC G Sbjct: 848 CAQKPCPRNSHCLQ--TGPSFHCLCLQGWTGPLCNLPLSSCQKAALSQGIDVSSLCHNGG 905 Query: 374 KCMNTADSYKCACPVTYTGKNCE 442 C+++ SY C CP + G C+ Sbjct: 906 LCVDSGPSYFCHCPPGFQGSLCQ 928 Score = 33.9 bits (74), Expect = 0.36 Identities = 21/75 (28%), Positives = 27/75 (36%), Gaps = 4/75 (5%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLC-GPGKCMNTADS-- 397 C C G + + C C PG G C+ + C C G C TA S Sbjct: 1010 CLDQPCHPTGTAACHSLANAFYCQCLPGHTGQWCEVEIDPCHSQPCFHGGTCEATAGSPL 1069 Query: 398 -YKCACPVTYTGKNC 439 + C CP + G C Sbjct: 1070 GFICHCPKGFEGPTC 1084 Score = 33.1 bits (72), Expect = 0.63 Identities = 18/51 (35%), Positives = 21/51 (41%), Gaps = 2/51 (3%) Frame = +2 Query: 233 PNLCLNNGVCQEA--LTEHGYVCLCAPGFGGNNCDRIGESCRPGLCGPGKC 379 P+ CL NG C E L G+ C C G C + G G G G C Sbjct: 1137 PSPCLYNGSCSETTGLGGPGFRCSCPHSSPGPRCQKPGAKGCEGRSGDGAC 1187 Score = 31.9 bits (69), Expect = 1.5 Identities = 23/86 (26%), Positives = 38/86 (44%), Gaps = 13/86 (15%) Frame = +2 Query: 224 TCAPNLCLNNGVCQEALTEHGYV--CLCAPGFGGNNCDRIGESCRPGLCGP-------GK 376 +C + C + G+C + + G+ C C G+GG +C + G CGP G Sbjct: 1090 SCGFHHCHHGGLCLPS-PKPGFPPRCACLSGYGGPDC--LTPPAPKG-CGPPSPCLYNGS 1145 Query: 377 CMNTAD----SYKCACPVTYTGKNCE 442 C T ++C+CP + G C+ Sbjct: 1146 CSETTGLGGPGFRCSCPHSSPGPRCQ 1171 >AL662884-27|CAI18362.1| 2003|Homo sapiens Notch homolog 4 (Drosophila) protein. Length = 2003 Score = 65.7 bits (153), Expect = 1e-10 Identities = 32/105 (30%), Positives = 48/105 (45%), Gaps = 1/105 (0%) Frame = +2 Query: 203 ENVQNCFTCAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLCGPGK-C 379 E+V C T P C N G CQ + + C+C G+GG +C+ + C C PG C Sbjct: 313 EDVDECETQGPPHCRNGGTCQNSAGS--FHCVCVSGWGGTSCEENLDDCIAATCAPGSTC 370 Query: 380 MNTADSYKCACPVTYTGKNCEVKQLIEYPAFTGSA*LAIKPPTST 514 ++ S+ C CP TG C ++ + G A + P T + Sbjct: 371 IDRVGSFSCLCPPGRTGLLCHLEDMCLSQPCHGDAQCSTNPLTGS 415 Score = 64.1 bits (149), Expect = 3e-10 Identities = 31/77 (40%), Positives = 40/77 (51%), Gaps = 3/77 (3%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESC--RPGLCGPG-KCMNTADS 397 C+ N C+N GVC + C C PGF G+ C+R C PG C G C NT S Sbjct: 160 CSANPCVNGGVCLATYPQ--IQCHCPPGFEGHACERDVNECFQDPGPCPKGTSCHNTLGS 217 Query: 398 YKCACPVTYTGKNCEVK 448 ++C CPV G CE++ Sbjct: 218 FQCLCPVGQEGPRCELR 234 Score = 61.3 bits (142), Expect = 2e-09 Identities = 28/74 (37%), Positives = 39/74 (52%), Gaps = 3/74 (4%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHG--YVCLCAPGFGGNNCDRIGESCRPGLC-GPGKCMNTADS 397 C P C N G CQ + ++CLC PGF G +C+ ++C C G C + D+ Sbjct: 238 CPPRGCSNGGTCQLMPEKDSTFHLCLCPPGFIGPDCEVNPDNCVSHQCQNGGTCQDGLDT 297 Query: 398 YKCACPVTYTGKNC 439 Y C CP T+TG +C Sbjct: 298 YTCLCPETWTGWDC 311 Score = 59.7 bits (138), Expect = 6e-09 Identities = 28/89 (31%), Positives = 44/89 (49%), Gaps = 3/89 (3%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLC-GPGKCMNTADSYK 403 CA CLN+ C + L +G+ C+C PGF G C+ + CR C G+C + ++ Sbjct: 517 CASAPCLNHADCHDLL--NGFQCICLPGFSGTRCEEDIDECRSSPCANGGQCQDQPGAFH 574 Query: 404 CACPVTYTGKNC--EVKQLIEYPAFTGSA 484 C C + G C EV + + P G++ Sbjct: 575 CKCLPGFEGPRCQTEVDECLSDPCPVGAS 603 Score = 59.7 bits (138), Expect = 6e-09 Identities = 30/90 (33%), Positives = 43/90 (47%), Gaps = 4/90 (4%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLC-GPGKCMNTADSYK 403 C C N C + GY+C CAPG+ G NC + ++C+ C G C + Sbjct: 934 CESRPCQNGATCMAQPS--GYLCQCAPGYDGQNCSKELDACQSQPCHNHGTCTPKPGGFH 991 Query: 404 CACPVTYTGKNCE--VKQLIEYPAF-TGSA 484 CACP + G CE V + ++ P TG+A Sbjct: 992 CACPPGFVGLRCEGDVDECLDQPCHPTGTA 1021 Score = 57.6 bits (133), Expect = 3e-08 Identities = 29/93 (31%), Positives = 38/93 (40%), Gaps = 8/93 (8%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLCGP------GKCMNT 388 C C + C +CLC PG+ G C + + C GP G C+NT Sbjct: 396 CLSQPCHGDAQCSTNPLTGSTLCLCQPGYSGPTCHQDLDECLMAQQGPSPCEHGGSCLNT 455 Query: 389 ADSYKCACPVTYTGKNCEV--KQLIEYPAFTGS 481 S+ C CP YTG CE + + P GS Sbjct: 456 PGSFNCLCPPGYTGSRCEADHNECLSQPCHPGS 488 Score = 54.0 bits (124), Expect = 3e-07 Identities = 25/74 (33%), Positives = 35/74 (47%), Gaps = 1/74 (1%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLCGPG-KCMNTADSYK 403 C + C N G CQ+ + C C PGF G C + C C G C++ ++ Sbjct: 555 CRSSPCANGGQCQDQ--PGAFHCKCLPGFEGPRCQTEVDECLSDPCPVGASCLDLPGAFF 612 Query: 404 CACPVTYTGKNCEV 445 C CP +TG+ CEV Sbjct: 613 CLCPSGFTGQLCEV 626 Score = 52.8 bits (121), Expect = 7e-07 Identities = 24/73 (32%), Positives = 36/73 (49%), Gaps = 1/73 (1%) Frame = +2 Query: 233 PNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLCGPGK-CMNTADSYKCA 409 P+ C + G C T + CLC PG+ G+ C+ C C PG C++ ++ C Sbjct: 443 PSPCEHGGSCLN--TPGSFNCLCPPGYTGSRCEADHNECLSQPCHPGSTCLDLLATFHCL 500 Query: 410 CPVTYTGKNCEVK 448 CP G+ CEV+ Sbjct: 501 CPPGLEGQLCEVE 513 Score = 52.8 bits (121), Expect = 7e-07 Identities = 26/87 (29%), Positives = 35/87 (40%), Gaps = 3/87 (3%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLC-GPGKCMNTADSYK 403 C C + G C + GY C C G+ G C +C G C G C + Y Sbjct: 695 CISAPCAHGGTCYPQPS--GYNCTCPTGYTGPTCSEEMTACHSGPCLNGGSCNPSPGGYY 752 Query: 404 CACPVTYTGKNCEVK--QLIEYPAFTG 478 C CP ++TG C+ + P F G Sbjct: 753 CTCPPSHTGPQCQTSTDYCVSAPCFNG 779 Score = 51.2 bits (117), Expect = 2e-06 Identities = 26/76 (34%), Positives = 35/76 (46%), Gaps = 4/76 (5%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCR---PGLC-GPGKCMNTAD 394 C + C N G CQ+ L Y CLC + G +C + C P C G C N+A Sbjct: 280 CVSHQCQNGGTCQDGLDT--YTCLCPETWTGWDCSEDVDECETQGPPHCRNGGTCQNSAG 337 Query: 395 SYKCACPVTYTGKNCE 442 S+ C C + G +CE Sbjct: 338 SFHCVCVSGWGGTSCE 353 Score = 51.2 bits (117), Expect = 2e-06 Identities = 24/75 (32%), Positives = 31/75 (41%), Gaps = 1/75 (1%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLC-GPGKCMNTADSYK 403 C CLN G C + GY C C P G C + C C G C+N ++ Sbjct: 733 CHSGPCLNGGSCNPS--PGGYYCTCPPSHTGPQCQTSTDYCVSAPCFNGGTCVNRPGTFS 790 Query: 404 CACPVTYTGKNCEVK 448 C C + + G CE K Sbjct: 791 CLCAMGFQGPRCEGK 805 Score = 50.4 bits (115), Expect = 4e-06 Identities = 25/69 (36%), Positives = 31/69 (44%), Gaps = 1/69 (1%) Frame = +2 Query: 236 NLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLCGPG-KCMNTADSYKCAC 412 +LC N G+C ++ Y C C PGF G+ C C C G CM Y C C Sbjct: 899 SLCHNGGLCVDS--GPSYFCHCPPGFQGSLCQDHVNPCESRPCQNGATCMAQPSGYLCQC 956 Query: 413 PVTYTGKNC 439 Y G+NC Sbjct: 957 APGYDGQNC 965 Score = 50.0 bits (114), Expect = 5e-06 Identities = 24/74 (32%), Positives = 33/74 (44%), Gaps = 2/74 (2%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCD-RIGESCRPGLC-GPGKCMNTADSY 400 C C N G C + CLCA GF G C+ ++ SC C C ++ Sbjct: 771 CVSAPCFNGGTCVNR--PGTFSCLCAMGFQGPRCEGKLRPSCADSPCRNRATCQDSPQGP 828 Query: 401 KCACPVTYTGKNCE 442 +C CP YTG +C+ Sbjct: 829 RCLCPTGYTGGSCQ 842 Score = 50.0 bits (114), Expect = 5e-06 Identities = 23/75 (30%), Positives = 35/75 (46%), Gaps = 1/75 (1%) Frame = +2 Query: 224 TCAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLCGPGK-CMNTADSY 400 +CA + C N CQ++ G CLC G+ G +C + + C C C+ T S+ Sbjct: 809 SCADSPCRNRATCQDS--PQGPRCLCPTGYTGGSCQTLMDLCAQKPCPRNSHCLQTGPSF 866 Query: 401 KCACPVTYTGKNCEV 445 C C +TG C + Sbjct: 867 HCLCLQGWTGPLCNL 881 Score = 49.2 bits (112), Expect = 9e-06 Identities = 28/86 (32%), Positives = 39/86 (45%), Gaps = 7/86 (8%) Frame = +2 Query: 212 QNCF----TCAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLCGP--- 370 QNC C C N+G C G+ C C PGF G C+ + C C P Sbjct: 963 QNCSKELDACQSQPCHNHGTCTPK--PGGFHCACPPGFVGLRCEGDVDECLDQPCHPTGT 1020 Query: 371 GKCMNTADSYKCACPVTYTGKNCEVK 448 C + A+++ C C +TG+ CEV+ Sbjct: 1021 AACHSLANAFYCQCLPGHTGQWCEVE 1046 Score = 46.8 bits (106), Expect = 5e-05 Identities = 22/76 (28%), Positives = 37/76 (48%), Gaps = 4/76 (5%) Frame = +2 Query: 287 YVCLCAPGFGGNNCD-RIGESCRPGLCGP-GKC-MNTADSYKCACPVTYTGKNCEVKQLI 457 ++C C PGF G C ++ + C P C G+C + + +C+C +TG+ C+++ Sbjct: 101 FLCTCLPGFTGERCQAKLEDPCPPSFCSKRGRCHIQASGRPQCSCMPGWTGEQCQLRDFC 160 Query: 458 E-YPAFTGSA*LAIKP 502 P G LA P Sbjct: 161 SANPCVNGGVCLATYP 176 Score = 41.5 bits (93), Expect = 0.002 Identities = 24/75 (32%), Positives = 30/75 (40%), Gaps = 4/75 (5%) Frame = +2 Query: 227 CAP---NLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLCGPG-KCMNTAD 394 CAP N ++G CQ + C+C G+ G C+ C C G C Sbjct: 658 CAPPEDNCTCHHGHCQRSS------CVCDVGWTGPECEAELGGCISAPCAHGGTCYPQPS 711 Query: 395 SYKCACPVTYTGKNC 439 Y C CP YTG C Sbjct: 712 GYNCTCPTGYTGPTC 726 Score = 40.7 bits (91), Expect = 0.003 Identities = 24/74 (32%), Positives = 34/74 (45%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLCGPGKCMNTADSYKC 406 CAPNLC +C++ + CLC G G C ++C C G C ++ C Sbjct: 629 CAPNLCQPKQICKDQKDKAN--CLCPDGSPG--CAPPEDNC---TCHHGHCQRSS----C 677 Query: 407 ACPVTYTGKNCEVK 448 C V +TG CE + Sbjct: 678 VCDVGWTGPECEAE 691 Score = 39.9 bits (89), Expect = 0.006 Identities = 27/87 (31%), Positives = 35/87 (40%), Gaps = 5/87 (5%) Frame = +2 Query: 200 KENVQNCFTCAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLCGPG-- 373 + +V CF P C C L + CLC G G C+ C P C G Sbjct: 192 ERDVNECFQ-DPGPCPKGTSCHNTLGS--FQCLCPVGQEGPRCELRAGPCPPRGCSNGGT 248 Query: 374 -KCMNTADS--YKCACPVTYTGKNCEV 445 + M DS + C CP + G +CEV Sbjct: 249 CQLMPEKDSTFHLCLCPPGFIGPDCEV 275 Score = 39.1 bits (87), Expect = 0.010 Identities = 19/73 (26%), Positives = 28/73 (38%), Gaps = 1/73 (1%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLC-GPGKCMNTADSYK 403 C C C + L + CLC PG G C+ C C C + + ++ Sbjct: 479 CLSQPCHPGSTCLDLLAT--FHCLCPPGLEGQLCEVETNECASAPCLNHADCHDLLNGFQ 536 Query: 404 CACPVTYTGKNCE 442 C C ++G CE Sbjct: 537 CICLPGFSGTRCE 549 Score = 38.7 bits (86), Expect = 0.013 Identities = 24/78 (30%), Positives = 31/78 (39%), Gaps = 7/78 (8%) Frame = +2 Query: 227 CAPNLCLNNGVCQE-ALTEHGYVCLCAPGFGGNNCDRIGESC------RPGLCGPGKCMN 385 C C + G C+ A + G++C C GF G C SC GLC P Sbjct: 1050 CHSQPCFHGGTCEATAGSPLGFICHCPKGFEGPTCSHRAPSCGFHHCHHGGLCLPSP--K 1107 Query: 386 TADSYKCACPVTYTGKNC 439 +CAC Y G +C Sbjct: 1108 PGFPPRCACLSGYGGPDC 1125 Score = 37.9 bits (84), Expect = 0.022 Identities = 27/87 (31%), Positives = 33/87 (37%), Gaps = 15/87 (17%) Frame = +2 Query: 233 PNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCD-----------RIGESCR---PGLCG- 367 P C N G C G C CAPGF G C + G SC+ P G Sbjct: 32 PEPCANGGTCLSLSLGQG-TCQCAPGFLGETCQFPDPCQNAQLCQNGGSCQALLPAPLGL 90 Query: 368 PGKCMNTADSYKCACPVTYTGKNCEVK 448 P S+ C C +TG+ C+ K Sbjct: 91 PSSPSPLTPSFLCTCLPGFTGERCQAK 117 Score = 37.9 bits (84), Expect = 0.022 Identities = 25/83 (30%), Positives = 35/83 (42%), Gaps = 11/83 (13%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPG----------LC-GPG 373 CA C N C + T + CLC G+ G C+ SC+ LC G Sbjct: 848 CAQKPCPRNSHCLQ--TGPSFHCLCLQGWTGPLCNLPLSSCQKAALSQGIDVSSLCHNGG 905 Query: 374 KCMNTADSYKCACPVTYTGKNCE 442 C+++ SY C CP + G C+ Sbjct: 906 LCVDSGPSYFCHCPPGFQGSLCQ 928 Score = 33.9 bits (74), Expect = 0.36 Identities = 21/75 (28%), Positives = 27/75 (36%), Gaps = 4/75 (5%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLC-GPGKCMNTADS-- 397 C C G + + C C PG G C+ + C C G C TA S Sbjct: 1010 CLDQPCHPTGTAACHSLANAFYCQCLPGHTGQWCEVEIDPCHSQPCFHGGTCEATAGSPL 1069 Query: 398 -YKCACPVTYTGKNC 439 + C CP + G C Sbjct: 1070 GFICHCPKGFEGPTC 1084 Score = 33.1 bits (72), Expect = 0.63 Identities = 18/51 (35%), Positives = 21/51 (41%), Gaps = 2/51 (3%) Frame = +2 Query: 233 PNLCLNNGVCQEA--LTEHGYVCLCAPGFGGNNCDRIGESCRPGLCGPGKC 379 P+ CL NG C E L G+ C C G C + G G G G C Sbjct: 1137 PSPCLYNGSCSETTGLGGPGFRCSCPHSSPGPRCQKPGAKGCEGRSGDGAC 1187 Score = 31.9 bits (69), Expect = 1.5 Identities = 23/86 (26%), Positives = 38/86 (44%), Gaps = 13/86 (15%) Frame = +2 Query: 224 TCAPNLCLNNGVCQEALTEHGYV--CLCAPGFGGNNCDRIGESCRPGLCGP-------GK 376 +C + C + G+C + + G+ C C G+GG +C + G CGP G Sbjct: 1090 SCGFHHCHHGGLCLPS-PKPGFPPRCACLSGYGGPDC--LTPPAPKG-CGPPSPCLYNGS 1145 Query: 377 CMNTAD----SYKCACPVTYTGKNCE 442 C T ++C+CP + G C+ Sbjct: 1146 CSETTGLGGPGFRCSCPHSSPGPRCQ 1171 >AF308602-1|AAG33848.1| 2556|Homo sapiens NOTCH 1 protein. Length = 2556 Score = 65.7 bits (153), Expect = 1e-10 Identities = 33/83 (39%), Positives = 40/83 (48%), Gaps = 3/83 (3%) Frame = +2 Query: 203 ENVQNCFTCAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESC--RPGLCGPG- 373 ++ Q CA N C N G C E Y+C C P F G C + C +P LC G Sbjct: 136 KSCQQADPCASNPCANGGQCLPF--EASYICHCPPSFHGPTCRQDVNECGQKPRLCRHGG 193 Query: 374 KCMNTADSYKCACPVTYTGKNCE 442 C N SY+C C T+TG NCE Sbjct: 194 TCHNEVGSYRCVCRATHTGPNCE 216 Score = 65.7 bits (153), Expect = 1e-10 Identities = 28/74 (37%), Positives = 39/74 (52%), Gaps = 2/74 (2%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESC--RPGLCGPGKCMNTADSY 400 C + C N G C + + + + CLC PGF G+ C + C RP L G G C + + Sbjct: 988 CTESSCFNGGTCVDGI--NSFTCLCPPGFTGSYCQHVVNECDSRPCLLG-GTCQDGRGLH 1044 Query: 401 KCACPVTYTGKNCE 442 +C CP YTG NC+ Sbjct: 1045 RCTCPQGYTGPNCQ 1058 Score = 64.9 bits (151), Expect = 2e-10 Identities = 29/74 (39%), Positives = 36/74 (48%), Gaps = 1/74 (1%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLC-GPGKCMNTADSYK 403 C N C+N G C++ + G VC C GF G NC C C G C++ YK Sbjct: 757 CESNPCVNGGTCKDMTS--GIVCTCREGFSGPNCQTNINECASNPCLNKGTCIDDVAGYK 814 Query: 404 CACPVTYTGKNCEV 445 C C + YTG CEV Sbjct: 815 CNCLLPYTGATCEV 828 Score = 61.7 bits (143), Expect = 2e-09 Identities = 26/75 (34%), Positives = 36/75 (48%) Frame = +2 Query: 215 NCFTCAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLCGPGKCMNTAD 394 N C+ C G CQ+ ++ Y+C C G G NC+ + C C G C++ D Sbjct: 603 NINECSSQPCRLRGTCQDP--DNAYLCFCLKGTTGPNCEINLDDCASSPCDSGTCLDKID 660 Query: 395 SYKCACPVTYTGKNC 439 Y+CAC YTG C Sbjct: 661 GYECACEPGYTGSMC 675 Score = 60.9 bits (141), Expect = 3e-09 Identities = 25/72 (34%), Positives = 38/72 (52%), Gaps = 1/72 (1%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLC-GPGKCMNTADSYK 403 C+P+ C N G C+ + + C C PGF G NC+ + C C G C++ ++Y Sbjct: 222 CSPSPCQNGGTCRPT-GDVTHECACLPGFTGQNCEENIDDCPGNNCKNGGACVDGVNTYN 280 Query: 404 CACPVTYTGKNC 439 C CP +TG+ C Sbjct: 281 CPCPPEWTGQYC 292 Score = 60.5 bits (140), Expect = 4e-09 Identities = 29/78 (37%), Positives = 41/78 (52%), Gaps = 1/78 (1%) Frame = +2 Query: 215 NCFTCAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLCGPG-KCMNTA 391 N CA + CL+NG C + + E + C C GF G+ C + C C G KC++ Sbjct: 490 NTDECASSPCLHNGRCLDKINE--FQCECPTGFTGHLCQYDVDECASTPCKNGAKCLDGP 547 Query: 392 DSYKCACPVTYTGKNCEV 445 ++Y C C YTG +CEV Sbjct: 548 NTYTCVCTEGYTGTHCEV 565 Score = 60.1 bits (139), Expect = 5e-09 Identities = 30/82 (36%), Positives = 38/82 (46%), Gaps = 5/82 (6%) Frame = +2 Query: 212 QNCFT----CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLCGPG-K 376 +NC T C PN C N G C + + C C PGF G C+ C C G Sbjct: 903 RNCETDIDDCRPNPCHNGGSCTDGINTA--FCDCLPGFRGTFCEEDINECASDPCRNGAN 960 Query: 377 CMNTADSYKCACPVTYTGKNCE 442 C + DSY C CP ++G +CE Sbjct: 961 CTDCVDSYTCTCPAGFSGIHCE 982 Score = 59.3 bits (137), Expect = 8e-09 Identities = 26/74 (35%), Positives = 38/74 (51%), Gaps = 1/74 (1%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLC-GPGKCMNTADSYK 403 C+P+ C N C + L GY C C G+ G NC + C C G C++ ++YK Sbjct: 1150 CSPSPCQNGATCTDYLG--GYSCKCVAGYHGVNCSEEIDECLSHPCQNGGTCLDLPNTYK 1207 Query: 404 CACPVTYTGKNCEV 445 C+CP G +CE+ Sbjct: 1208 CSCPRGTQGVHCEI 1221 Score = 58.8 bits (136), Expect = 1e-08 Identities = 24/77 (31%), Positives = 37/77 (48%) Frame = +2 Query: 215 NCFTCAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLCGPGKCMNTAD 394 N CA N C N G C++ + +G+ C C G+ C C C G C ++ + Sbjct: 678 NIDECAGNPCHNGGTCEDGI--NGFTCRCPEGYHDPTCLSEVNECNSNPCVHGACRDSLN 735 Query: 395 SYKCACPVTYTGKNCEV 445 YKC C ++G NC++ Sbjct: 736 GYKCDCDPGWSGTNCDI 752 Score = 58.0 bits (134), Expect = 2e-08 Identities = 26/74 (35%), Positives = 36/74 (48%), Gaps = 2/74 (2%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLC-APGFGGNNCDRIGESCRPGLCGPG-KCMNTADSY 400 CAP+ C N G C+++ + C+C G G C+ C C G C NT Y Sbjct: 833 CAPSPCRNGGECRQSEDYESFSCVCPTAGAKGQTCEVDINECVLSPCRHGASCQNTHGXY 892 Query: 401 KCACPVTYTGKNCE 442 +C C Y+G+NCE Sbjct: 893 RCHCQAGYSGRNCE 906 Score = 57.2 bits (132), Expect = 3e-08 Identities = 22/73 (30%), Positives = 39/73 (53%), Gaps = 1/73 (1%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLC-GPGKCMNTADSYK 403 C N C N+ C + + E + C+C PG+ G +C+ + C C G+C++ + ++ Sbjct: 456 CVSNPCQNDATCLDQIGE--FQCMCMPGYEGVHCEVNTDECASSPCLHNGRCLDKINEFQ 513 Query: 404 CACPVTYTGKNCE 442 C CP +TG C+ Sbjct: 514 CECPTGFTGHLCQ 526 Score = 56.8 bits (131), Expect = 5e-08 Identities = 27/74 (36%), Positives = 33/74 (44%), Gaps = 1/74 (1%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLC-GPGKCMNTADSYK 403 C CL G CQ+ H C C G+ G NC + C C GKC T Y+ Sbjct: 1026 CDSRPCLLGGTCQDGRGLHR--CTCPQGYTGPNCQNLVHWCDSSPCKNGGKCWQTHTQYR 1083 Query: 404 CACPVTYTGKNCEV 445 C CP +TG C+V Sbjct: 1084 CECPSGWTGLYCDV 1097 Score = 55.2 bits (127), Expect = 1e-07 Identities = 26/72 (36%), Positives = 35/72 (48%), Gaps = 1/72 (1%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLC-GPGKCMNTADSYK 403 C N C N G C + LT Y C C PG+ G +C + + C C G+C+ SY Sbjct: 106 CLTNPCRNGGTC-DLLTLTEYKCRCPPGWSGKSCQQ-ADPCASNPCANGGQCLPFEASYI 163 Query: 404 CACPVTYTGKNC 439 C CP ++ G C Sbjct: 164 CHCPPSFHGPTC 175 Score = 55.2 bits (127), Expect = 1e-07 Identities = 29/83 (34%), Positives = 41/83 (49%), Gaps = 2/83 (2%) Frame = +2 Query: 200 KENVQNCFTCAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLC-GPGK 376 +++V C P LC + G C + Y C+C G NC+R C P C G Sbjct: 176 RQDVNECGQ-KPRLCRHGGTCHNEVGS--YRCVCRATHTGPNCERPYVPCSPSPCQNGGT 232 Query: 377 CMNTAD-SYKCACPVTYTGKNCE 442 C T D +++CAC +TG+NCE Sbjct: 233 CRPTGDVTHECACLPGFTGQNCE 255 Score = 55.2 bits (127), Expect = 1e-07 Identities = 23/72 (31%), Positives = 34/72 (47%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLCGPGKCMNTADSYKC 406 CA C N C + + Y C+C G+ G +C+ + C P C G C + ++ C Sbjct: 532 CASTPCKNGAKCLDG--PNTYTCVCTEGYTGTHCEVDIDECDPDPCHYGSCKDGVATFTC 589 Query: 407 ACPVTYTGKNCE 442 C YTG +CE Sbjct: 590 LCRPGYTGHHCE 601 Score = 55.2 bits (127), Expect = 1e-07 Identities = 25/73 (34%), Positives = 36/73 (49%), Gaps = 1/73 (1%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLC-GPGKCMNTADSYK 403 C N C++ G C+++L +GY C C PG+ G NCD C C G C + Sbjct: 720 CNSNPCVH-GACRDSL--NGYKCDCDPGWSGTNCDINNNECESNPCVNGGTCKDMTSGIV 776 Query: 404 CACPVTYTGKNCE 442 C C ++G NC+ Sbjct: 777 CTCREGFSGPNCQ 789 Score = 55.2 bits (127), Expect = 1e-07 Identities = 24/70 (34%), Positives = 32/70 (45%), Gaps = 3/70 (4%) Frame = +2 Query: 242 CLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLC---GPGKCMNTADSYKCAC 412 C NNG C + + GY C C PGF G C+ C C G C+ + + C C Sbjct: 1239 CFNNGTCVDQVG--GYSCTCPPGFVGERCEGDVNECLSNPCDARGTQNCVQRVNDFHCEC 1296 Query: 413 PVTYTGKNCE 442 +TG+ CE Sbjct: 1297 RAGHTGRRCE 1306 Score = 54.4 bits (125), Expect = 2e-07 Identities = 26/83 (31%), Positives = 39/83 (46%), Gaps = 3/83 (3%) Frame = +2 Query: 239 LCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLCGPG-KCMNTADSYKCACP 415 LC + G+C +A H C C G+ G+ C+ + + C P C G C + Y C C Sbjct: 1116 LCQHGGLCVDAGNTHH--CRCQAGYTGSYCEDLVDECSPSPCQNGATCTDYLGGYSCKCV 1173 Query: 416 VTYTGKNC--EVKQLIEYPAFTG 478 Y G NC E+ + + +P G Sbjct: 1174 AGYHGVNCSEEIDECLSHPCQNG 1196 Score = 54.0 bits (124), Expect = 3e-07 Identities = 29/81 (35%), Positives = 38/81 (46%), Gaps = 4/81 (4%) Frame = +2 Query: 215 NCFTCAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLC-GPGKCMNTA 391 N CA N CLN G C + + GY C C + G C+ + C P C G+C + Sbjct: 791 NINECASNPCLNKGTCIDDVA--GYKCNCLLPYTGATCEVVLAPCAPSPCRNGGECRQSE 848 Query: 392 D--SYKCACPVT-YTGKNCEV 445 D S+ C CP G+ CEV Sbjct: 849 DYESFSCVCPTAGAKGQTCEV 869 Score = 54.0 bits (124), Expect = 3e-07 Identities = 23/73 (31%), Positives = 34/73 (46%), Gaps = 1/73 (1%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLC-GPGKCMNTADSYK 403 CA + C N C + + Y C C GF G +C+ C C G C++ +S+ Sbjct: 950 CASDPCRNGANCTDCVDS--YTCTCPAGFSGIHCENNTPDCTESSCFNGGTCVDGINSFT 1007 Query: 404 CACPVTYTGKNCE 442 C CP +TG C+ Sbjct: 1008 CLCPPGFTGSYCQ 1020 Score = 51.6 bits (118), Expect = 2e-06 Identities = 26/79 (32%), Positives = 35/79 (44%), Gaps = 3/79 (3%) Frame = +2 Query: 212 QNCFTCAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCR--PGLC-GPGKCM 382 +N C N C N G C + + Y C C P + G C + C+ P C G C Sbjct: 256 ENIDDCPGNNCKNGGACVDGVNT--YNCPCPPEWTGQYCTEDVDECQLMPNACQNGGTCH 313 Query: 383 NTADSYKCACPVTYTGKNC 439 NT Y C C +TG++C Sbjct: 314 NTHGGYNCVCVNGWTGEDC 332 Score = 51.2 bits (117), Expect = 2e-06 Identities = 25/76 (32%), Positives = 33/76 (43%), Gaps = 3/76 (3%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGL--CG-PGKCMNTADS 397 C N C C +C C G+ G C + + C G C GKC+NT S Sbjct: 376 CISNPCNEGSNCDTNPVNGKAICTCPSGYTGPACSQDVDECSLGANPCEHAGKCINTLGS 435 Query: 398 YKCACPVTYTGKNCEV 445 ++C C YTG CE+ Sbjct: 436 FECQCLQGYTGPRCEI 451 Score = 50.8 bits (116), Expect = 3e-06 Identities = 24/74 (32%), Positives = 38/74 (51%), Gaps = 1/74 (1%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLCG-PGKCMNTADSYK 403 C P+ C + G C++ + + CLC PG+ G++C+ C C G C + ++Y Sbjct: 570 CDPDPC-HYGSCKDGVAT--FTCLCRPGYTGHHCETNINECSSQPCRLRGTCQDPDNAYL 626 Query: 404 CACPVTYTGKNCEV 445 C C TG NCE+ Sbjct: 627 CFCLKGTTGPNCEI 640 Score = 49.6 bits (113), Expect = 7e-06 Identities = 24/74 (32%), Positives = 32/74 (43%), Gaps = 2/74 (2%) Frame = +2 Query: 227 CAPNLCLNNGVCQEAL-TEHGYVCLCAPGFGGNNCDRIGESCRPGLC-GPGKCMNTADSY 400 C C N G C A T G++C C GF G C+ +C C G C++ S Sbjct: 1312 CKGKPCKNGGTCAVASNTARGFICKCPAGFEGATCENDARTCGSLRCLNGGTCISGPRSP 1371 Query: 401 KCACPVTYTGKNCE 442 C C +TG C+ Sbjct: 1372 TCLCLGPFTGPECQ 1385 Score = 48.4 bits (110), Expect = 2e-05 Identities = 27/92 (29%), Positives = 41/92 (44%), Gaps = 3/92 (3%) Frame = +2 Query: 215 NCFTCAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLC-GPGKCMNTA 391 N CA + C ++G C + + GY C C PG+ G+ C+ + C C G C + Sbjct: 641 NLDDCASSPC-DSGTCLDKID--GYECACEPGYTGSMCNSNIDECAGNPCHNGGTCEDGI 697 Query: 392 DSYKCACPVTYTGKNC--EVKQLIEYPAFTGS 481 + + C CP Y C EV + P G+ Sbjct: 698 NGFTCRCPEGYHDPTCLSEVNECNSNPCVHGA 729 Score = 46.8 bits (106), Expect = 5e-05 Identities = 27/78 (34%), Positives = 35/78 (44%), Gaps = 6/78 (7%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHG---YVCLCAPGFGGNNC-DRIGESCRPGLC-GPGKC-MNT 388 C C N G C + G Y C CA GF G C + +C C G C + T Sbjct: 63 CLSTPCKNAGTCH-VVDRRGVADYACSCALGFSGPLCLTPLDNACLTNPCRNGGTCDLLT 121 Query: 389 ADSYKCACPVTYTGKNCE 442 YKC CP ++GK+C+ Sbjct: 122 LTEYKCRCPPGWSGKSCQ 139 Score = 46.8 bits (106), Expect = 5e-05 Identities = 23/73 (31%), Positives = 32/73 (43%), Gaps = 1/73 (1%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLC-GPGKCMNTADSYK 403 C + C + CQ T Y C C G+ G NC+ + CRP C G C + ++ Sbjct: 874 CVLSPCRHGASCQN--THGXYRCHCQAGYSGRNCETDIDDCRPNPCHNGGSCTDGINTAF 931 Query: 404 CACPVTYTGKNCE 442 C C + G CE Sbjct: 932 CDCLPGFRGTFCE 944 Score = 45.6 bits (103), Expect = 1e-04 Identities = 34/99 (34%), Positives = 42/99 (42%), Gaps = 5/99 (5%) Frame = +2 Query: 224 TCAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGES-CRPGL-C-GPGKCMNTAD 394 TC CLN G C CLC F G C S C G C G C T++ Sbjct: 1352 TCGSLRCLNGGTCISG--PRSPTCLCLGPFTGPECQFPASSPCLGGNPCYNQGTCEPTSE 1409 Query: 395 S--YKCACPVTYTGKNCEVKQLIEYPAFTGSA*LAIKPP 505 S Y+C CP + G C + ++Y +F G A I PP Sbjct: 1410 SPFYRCLCPAKFNGLLCHI---LDY-SFGGGAGRDIPPP 1444 Score = 43.2 bits (97), Expect = 6e-04 Identities = 31/91 (34%), Positives = 40/91 (43%), Gaps = 12/91 (13%) Frame = +2 Query: 206 NVQNCFT-CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESC-----RPG--- 358 N QN C + C N G C + T+ Y C C G+ G CD SC R G Sbjct: 1056 NCQNLVHWCDSSPCKNGGKCWQTHTQ--YRCECPSGWTGLYCDVPSVSCEVAAQRQGVDV 1113 Query: 359 --LCGPGK-CMNTADSYKCACPVTYTGKNCE 442 LC G C++ +++ C C YTG CE Sbjct: 1114 ARLCQHGGLCVDAGNTHHCRCQAGYTGSYCE 1144 Score = 43.2 bits (97), Expect = 6e-04 Identities = 23/81 (28%), Positives = 34/81 (41%), Gaps = 9/81 (11%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGL--------C-GPGKC 379 C + C N G C + + Y C C G G +C+ + C P + C G C Sbjct: 1188 CLSHPCQNGGTCLDL--PNTYKCSCPRGTQGVHCEINVDDCNPPVDPVSRSPKCFNNGTC 1245 Query: 380 MNTADSYKCACPVTYTGKNCE 442 ++ Y C CP + G+ CE Sbjct: 1246 VDQVGGYSCTCPPGFVGERCE 1266 Score = 41.1 bits (92), Expect = 0.002 Identities = 22/76 (28%), Positives = 29/76 (38%), Gaps = 4/76 (5%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLC-GPGKC---MNTAD 394 C N C G + + C C G G C+ + C+ C G C NTA Sbjct: 1272 CLSNPCDARGTQNCVQRVNDFHCECRAGHTGRRCESVINGCKGKPCKNGGTCAVASNTAR 1331 Query: 395 SYKCACPVTYTGKNCE 442 + C CP + G CE Sbjct: 1332 GFICKCPAGFEGATCE 1347 Score = 40.3 bits (90), Expect = 0.004 Identities = 22/82 (26%), Positives = 34/82 (41%), Gaps = 1/82 (1%) Frame = +2 Query: 203 ENVQNCFTCAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLC-GPGKC 379 ++V C + N C + G C L + C C G+ G C+ C C C Sbjct: 411 QDVDEC-SLGANPCEHAGKCINTLGS--FECQCLQGYTGPRCEIDVNECVSNPCQNDATC 467 Query: 380 MNTADSYKCACPVTYTGKNCEV 445 ++ ++C C Y G +CEV Sbjct: 468 LDQIGEFQCMCMPGYEGVHCEV 489 Score = 32.3 bits (70), Expect = 1.1 Identities = 21/71 (29%), Positives = 29/71 (40%), Gaps = 5/71 (7%) Frame = +2 Query: 242 CLNNGVCQEALTEHGYVCLCAPGFGGNNCDR----IGESCR-PGLCGPGKCMNTADSYKC 406 CLN G C+ A C+C F G C + C+ G C AD Y C Sbjct: 31 CLNGGKCEAA--NGTEACVCGGAFVGPRCQDPNPCLSTPCKNAGTCHVVDRRGVAD-YAC 87 Query: 407 ACPVTYTGKNC 439 +C + ++G C Sbjct: 88 SCALGFSGPLC 98 >AK074062-1|BAB84888.1| 1282|Homo sapiens FLJ00133 protein protein. Length = 1282 Score = 64.9 bits (151), Expect = 2e-10 Identities = 27/75 (36%), Positives = 40/75 (53%), Gaps = 1/75 (1%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLC-GPGKCMNTADSYK 403 C CL+ G CQ+ + GY+CLC+ G+ G +C+ + CR C G C N +Y Sbjct: 626 CRSQPCLHGGSCQDRVA--GYLCLCSTGYEGAHCELERDECRAHPCRNGGSCRNLPGAYV 683 Query: 404 CACPVTYTGKNCEVK 448 C CP + G +CE + Sbjct: 684 CRCPAGFVGVHCETE 698 Score = 58.8 bits (136), Expect = 1e-08 Identities = 30/76 (39%), Positives = 41/76 (53%), Gaps = 3/76 (3%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIG--ESCRPGLC-GPGKCMNTADS 397 C+ C N G C+EA E Y C C F G +C+ IG +SC G C G C + Sbjct: 453 CSSGPCRNGGTCKEAGGE--YHCSCPYRFTGRHCE-IGKPDSCASGPCHNGGTCFHYIGK 509 Query: 398 YKCACPVTYTGKNCEV 445 YKC CP ++G++CE+ Sbjct: 510 YKCDCPPGFSGRHCEI 525 Score = 57.6 bits (133), Expect = 3e-08 Identities = 28/79 (35%), Positives = 36/79 (45%), Gaps = 6/79 (7%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLCGPGKCMN------T 388 C + C N G C + Y C C GF G +C E RP LC G C N Sbjct: 414 CDSDPCFNGGSCDAH--DDSYTCECPRGFHGKHC----EKARPHLCSSGPCRNGGTCKEA 467 Query: 389 ADSYKCACPVTYTGKNCEV 445 Y C+CP +TG++CE+ Sbjct: 468 GGEYHCSCPYRFTGRHCEI 486 Score = 54.4 bits (125), Expect = 2e-07 Identities = 23/72 (31%), Positives = 37/72 (51%), Gaps = 1/72 (1%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLCGP-GKCMNTADSYK 403 C + C + G C+ Y+C+C F G +C+ + + C CG G C+ + S+ Sbjct: 702 CDSSPCQHGGRCESG--GGAYLCVCPESFFGYHCETVSDPCFSSPCGGRGYCLASNGSHS 759 Query: 404 CACPVTYTGKNC 439 C C V YTG++C Sbjct: 760 CTCKVGYTGEDC 771 Score = 52.4 bits (120), Expect = 1e-06 Identities = 27/81 (33%), Positives = 35/81 (43%), Gaps = 3/81 (3%) Frame = +2 Query: 218 CFTCAPNLCLNNGVC-QEALTEH-GYVCLCAPGFGGNNCDRIGESCRPGLC-GPGKCMNT 388 C P CLN G C + +T + Y C C GF G C C C G C + Sbjct: 141 CLALRP--CLNGGKCIDDCVTGNPSYTCSCLSGFTGRRCHLDVNECASQPCQNGGTCTHG 198 Query: 389 ADSYKCACPVTYTGKNCEVKQ 451 +S++C CP + G CE Q Sbjct: 199 INSFRCQCPAGFGGPTCETAQ 219 Score = 52.4 bits (120), Expect = 1e-06 Identities = 25/76 (32%), Positives = 37/76 (48%), Gaps = 5/76 (6%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDR----IGESCRPGLC-GPGKCMNTA 391 C+P+ CLN G C + + Y CLCA F G C+ + ++C C G C++ Sbjct: 260 CSPDPCLNGGSCVDLVGN--YTCLCAEPFKGLRCETGDHPVPDACLSAPCHNGGTCVDAD 317 Query: 392 DSYKCACPVTYTGKNC 439 Y C CP + G +C Sbjct: 318 QGYVCECPEGFMGLDC 333 Score = 52.4 bits (120), Expect = 1e-06 Identities = 24/73 (32%), Positives = 36/73 (49%), Gaps = 1/73 (1%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLCGPG-KCMNTADSYK 403 C + C N G C+ YVC C GF G +C+ ++C C G +C + +Y Sbjct: 664 CRAHPCRNGGSCRNL--PGAYVCRCPAGFVGVHCETEVDACDSSPCQHGGRCESGGGAYL 721 Query: 404 CACPVTYTGKNCE 442 C CP ++ G +CE Sbjct: 722 CVCPESFFGYHCE 734 Score = 51.2 bits (117), Expect = 2e-06 Identities = 25/74 (33%), Positives = 31/74 (41%), Gaps = 1/74 (1%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLC-GPGKCMNTADSYK 403 CA C N G C + + + C C GFGG C+ C C G+C S Sbjct: 184 CASQPCQNGGTCTHGI--NSFRCQCPAGFGGPTCETAQSPCDTKECQHGGQCQVENGSAV 241 Query: 404 CACPVTYTGKNCEV 445 C C YTG CE+ Sbjct: 242 CVCQAGYTGAACEM 255 Score = 49.6 bits (113), Expect = 7e-06 Identities = 23/76 (30%), Positives = 33/76 (43%), Gaps = 1/76 (1%) Frame = +2 Query: 224 TCAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLC-GPGKCMNTADSY 400 +CA C N G C + + Y C C PGF G +C+ C C G C + + Sbjct: 491 SCASGPCHNGGTCFHYIGK--YKCDCPPGFSGRHCEIAPSPCFRSPCVNGGTCEDRDTDF 548 Query: 401 KCACPVTYTGKNCEVK 448 C C Y G+ C+ + Sbjct: 549 FCHCQAGYMGRRCQAE 564 Score = 48.8 bits (111), Expect = 1e-05 Identities = 24/74 (32%), Positives = 34/74 (45%), Gaps = 2/74 (2%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGY-VCLCAPGFGGNNCDRIGESCRPGLC-GPGKCMNTADSY 400 C C + G CQ E+G VC+C G+ G C+ + C P C G C++ +Y Sbjct: 222 CDTKECQHGGQCQ---VENGSAVCVCQAGYTGAACEMDVDDCSPDPCLNGGSCVDLVGNY 278 Query: 401 KCACPVTYTGKNCE 442 C C + G CE Sbjct: 279 TCLCAEPFKGLRCE 292 Score = 35.1 bits (77), Expect = 0.16 Identities = 14/35 (40%), Positives = 16/35 (45%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCD 331 C+ N C N G C H C C PGF G C+ Sbjct: 1180 CSENPCQNGGTCVPGADAHS--CDCGPGFKGRRCE 1212 Score = 31.9 bits (69), Expect = 1.5 Identities = 14/53 (26%), Positives = 24/53 (45%), Gaps = 1/53 (1%) Frame = +2 Query: 290 VCLCAPGFGGNNCDRIGESCRPGLC-GPGKCMNTADSYKCACPVTYTGKNCEV 445 + L P G + + +C C G C+ AD++ C C + G+ CE+ Sbjct: 1161 LALQLPEHGSKDIGNVPGNCSENPCQNGGTCVPGADAHSCDCGPGFKGRRCEL 1213 Score = 30.7 bits (66), Expect = 3.4 Identities = 24/85 (28%), Positives = 29/85 (34%), Gaps = 4/85 (4%) Frame = +2 Query: 242 CLNNGVCQEALTEHGYVCLCAPGFGGNNCDR--IGESCRPGLCGP--GKCMNTADSYKCA 409 C N G C A T +C C GF G C+ C P G CM SY C Sbjct: 343 CRNGGRCLGANTT---LCQCPLGFFGLLCEFEITAMPCNMNTQCPDGGYCMEHGGSYLCV 399 Query: 410 CPVTYTGKNCEVKQLIEYPAFTGSA 484 C + + P F G + Sbjct: 400 CHTDHNASHSLPSPCDSDPCFNGGS 424 Score = 30.3 bits (65), Expect = 4.5 Identities = 12/38 (31%), Positives = 18/38 (47%), Gaps = 1/38 (2%) Frame = +2 Query: 341 ESCRPGLC-GPGKCMNTADSYKCACPVTYTGKNCEVKQ 451 + CR C G C + Y C C Y G +CE+++ Sbjct: 624 DECRSQPCLHGGSCQDRVAGYLCLCSTGYEGAHCELER 661 >AF439717-1|AAQ04558.1| 1008|Homo sapiens insulin responsive sequence DNA binding protein-1 protein. Length = 1008 Score = 64.9 bits (151), Expect = 2e-10 Identities = 27/75 (36%), Positives = 40/75 (53%), Gaps = 1/75 (1%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLC-GPGKCMNTADSYK 403 C CL+ G CQ+ + GY+CLC+ G+ G +C+ + CR C G C N +Y Sbjct: 372 CRSQPCLHGGSCQDRVA--GYLCLCSTGYEGAHCELERDECRAHPCRNGGSCRNLPGAYV 429 Query: 404 CACPVTYTGKNCEVK 448 C CP + G +CE + Sbjct: 430 CRCPAGFVGVHCETE 444 Score = 57.6 bits (133), Expect = 3e-08 Identities = 28/79 (35%), Positives = 36/79 (45%), Gaps = 6/79 (7%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLCGPGKCMN------T 388 C + C N G C + Y C C GF G +C E RP LC G C N Sbjct: 160 CNSDPCFNGGSCDAH--DDSYTCECPRGFHGKHC----EKARPHLCSSGPCRNGGTCKEA 213 Query: 389 ADSYKCACPVTYTGKNCEV 445 Y C+CP +TG++CE+ Sbjct: 214 GGEYHCSCPYRFTGRHCEI 232 Score = 57.6 bits (133), Expect = 3e-08 Identities = 30/76 (39%), Positives = 40/76 (52%), Gaps = 3/76 (3%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIG--ESCRPGLC-GPGKCMNTADS 397 C+ C N G C+EA E Y C C F G +C+ IG +SC G C G C + Sbjct: 199 CSSGPCRNGGTCKEAGGE--YHCSCPYRFTGRHCE-IGKPDSCASGPCHNGGTCFHYIGK 255 Query: 398 YKCACPVTYTGKNCEV 445 YKC CP ++G+ CE+ Sbjct: 256 YKCDCPPGFSGRYCEI 271 Score = 56.8 bits (131), Expect = 5e-08 Identities = 24/72 (33%), Positives = 38/72 (52%), Gaps = 1/72 (1%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLC-GPGKCMNTADSYK 403 C + C + G C+ Y+C+C GF G +C+ + + C C G G C+ + S+ Sbjct: 448 CDSSPCQHGGRCESG--GGAYLCVCPEGFFGYHCETVSDPCFSSPCGGRGYCLASNGSHS 505 Query: 404 CACPVTYTGKNC 439 C C V YTG++C Sbjct: 506 CTCKVGYTGEDC 517 Score = 52.4 bits (120), Expect = 1e-06 Identities = 25/76 (32%), Positives = 37/76 (48%), Gaps = 5/76 (6%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDR----IGESCRPGLC-GPGKCMNTA 391 C+P+ CLN G C + + Y CLCA F G C+ + ++C C G C++ Sbjct: 6 CSPDPCLNGGSCVDLVGN--YTCLCAEPFKGLRCETGDHPVPDACLSAPCHNGGTCVDAD 63 Query: 392 DSYKCACPVTYTGKNC 439 Y C CP + G +C Sbjct: 64 QGYVCECPEGFMGLDC 79 Score = 51.2 bits (117), Expect = 2e-06 Identities = 24/73 (32%), Positives = 35/73 (47%), Gaps = 1/73 (1%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLCGPG-KCMNTADSYK 403 C + C N G C+ YVC C GF G +C+ ++C C G +C + +Y Sbjct: 410 CRAHPCRNGGSCRNL--PGAYVCRCPAGFVGVHCETEVDACDSSPCQHGGRCESGGGAYL 467 Query: 404 CACPVTYTGKNCE 442 C CP + G +CE Sbjct: 468 CVCPEGFFGYHCE 480 Score = 48.4 bits (110), Expect = 2e-05 Identities = 23/76 (30%), Positives = 32/76 (42%), Gaps = 1/76 (1%) Frame = +2 Query: 224 TCAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLC-GPGKCMNTADSY 400 +CA C N G C + + Y C C PGF G C+ C C G C + + Sbjct: 237 SCASGPCHNGGTCFHYIGK--YKCDCPPGFSGRYCEIAPSPCFRSPCVNGGTCEDRDTDF 294 Query: 401 KCACPVTYTGKNCEVK 448 C C Y G+ C+ + Sbjct: 295 FCHCQAGYMGRRCQAE 310 Score = 35.1 bits (77), Expect = 0.16 Identities = 14/35 (40%), Positives = 16/35 (45%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCD 331 C+ N C N G C H C C PGF G C+ Sbjct: 906 CSENPCQNGGTCVPGADAHS--CDCGPGFKGRRCE 938 Score = 31.9 bits (69), Expect = 1.5 Identities = 14/53 (26%), Positives = 24/53 (45%), Gaps = 1/53 (1%) Frame = +2 Query: 290 VCLCAPGFGGNNCDRIGESCRPGLC-GPGKCMNTADSYKCACPVTYTGKNCEV 445 + L P G + + +C C G C+ AD++ C C + G+ CE+ Sbjct: 887 LALQLPEHGSKDIGNVPGNCSENPCQNGGTCVPGADAHSCDCGPGFKGRRCEL 939 Score = 30.7 bits (66), Expect = 3.4 Identities = 24/85 (28%), Positives = 29/85 (34%), Gaps = 4/85 (4%) Frame = +2 Query: 242 CLNNGVCQEALTEHGYVCLCAPGFGGNNCDR--IGESCRPGLCGP--GKCMNTADSYKCA 409 C N G C A T +C C GF G C+ C P G CM SY C Sbjct: 89 CRNGGRCLGANTT---LCQCPLGFFGLLCEFEITAMPCNMNTQCPDGGYCMEHGGSYLCV 145 Query: 410 CPVTYTGKNCEVKQLIEYPAFTGSA 484 C + + P F G + Sbjct: 146 CHTDHNASHSLPSPCNSDPCFNGGS 170 Score = 30.3 bits (65), Expect = 4.5 Identities = 12/38 (31%), Positives = 18/38 (47%), Gaps = 1/38 (2%) Frame = +2 Query: 341 ESCRPGLC-GPGKCMNTADSYKCACPVTYTGKNCEVKQ 451 + CR C G C + Y C C Y G +CE+++ Sbjct: 370 DECRSQPCLHGGSCQDRVAGYLCLCSTGYEGAHCELER 407 Score = 29.9 bits (64), Expect = 5.9 Identities = 11/35 (31%), Positives = 16/35 (45%), Gaps = 1/35 (2%) Frame = +2 Query: 341 ESCRPGLC-GPGKCMNTADSYKCACPVTYTGKNCE 442 + C P C G C++ +Y C C + G CE Sbjct: 4 DDCSPDPCLNGGSCVDLVGNYTCLCAEPFKGLRCE 38 >U70312-1|AAC02648.1| 480|Homo sapiens integrin binding protein Del-1 protein. Length = 480 Score = 64.5 bits (150), Expect = 2e-10 Identities = 33/97 (34%), Positives = 47/97 (48%), Gaps = 6/97 (6%) Frame = +2 Query: 176 NIMALALEKENVQNCFTCAPNLCLNNGVCQ--EAL---TEHGYVCLCAPGFGGNNCDRIG 340 +++ +A ++E + C PN C N G C+ EA T GYVC C GF G +C Sbjct: 61 SVVEVASDEEEPTSAGPCTPNPCHNGGTCEISEAYRGDTFIGYVCKCPRGFNGIHCQHNI 120 Query: 341 ESCRPGLC-GPGKCMNTADSYKCACPVTYTGKNCEVK 448 C C G C + +Y C CP + G+NC+ K Sbjct: 121 NECEVEPCKNGGICTDLVANYSCECPGEFMGRNCQYK 157 Score = 43.6 bits (98), Expect = 4e-04 Identities = 27/92 (29%), Positives = 34/92 (36%), Gaps = 20/92 (21%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRI-------GESCRPGLCGPGKCMN 385 C PN C N G+C L + + C C GF NC + E G C P C N Sbjct: 26 CDPNPCENGGICLPGLADGSFSCECPDGFTDPNCSSVVEVASDEEEPTSAGPCTPNPCHN 85 Query: 386 -------------TADSYKCACPVTYTGKNCE 442 T Y C CP + G +C+ Sbjct: 86 GGTCEISEAYRGDTFIGYVCKCPRGFNGIHCQ 117 >BC030828-1|AAH30828.1| 480|Homo sapiens EGF-like repeats and discoidin I-like domains 3 protein. Length = 480 Score = 64.5 bits (150), Expect = 2e-10 Identities = 33/97 (34%), Positives = 47/97 (48%), Gaps = 6/97 (6%) Frame = +2 Query: 176 NIMALALEKENVQNCFTCAPNLCLNNGVCQ--EAL---TEHGYVCLCAPGFGGNNCDRIG 340 +++ +A ++E + C PN C N G C+ EA T GYVC C GF G +C Sbjct: 61 SVVEVASDEEEPTSAGPCTPNPCHNGGTCEISEAYRGDTFIGYVCKCPRGFNGIHCQHNI 120 Query: 341 ESCRPGLC-GPGKCMNTADSYKCACPVTYTGKNCEVK 448 C C G C + +Y C CP + G+NC+ K Sbjct: 121 NECEVEPCKNGGICTDLVANYSCECPGEFMGRNCQYK 157 Score = 43.6 bits (98), Expect = 4e-04 Identities = 27/92 (29%), Positives = 34/92 (36%), Gaps = 20/92 (21%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRI-------GESCRPGLCGPGKCMN 385 C PN C N G+C L + + C C GF NC + E G C P C N Sbjct: 26 CDPNPCENGGICLPGLADGSFSCECPDGFTDPNCSSVVEVASDEEEPTSAGPCTPNPCHN 85 Query: 386 -------------TADSYKCACPVTYTGKNCE 442 T Y C CP + G +C+ Sbjct: 86 GGTCEISEAYRGDTFIGYVCKCPRGFNGIHCQ 117 >U89335-1|AAC63097.1| 1999|Homo sapiens notch4 protein. Length = 1999 Score = 64.1 bits (149), Expect = 3e-10 Identities = 31/77 (40%), Positives = 40/77 (51%), Gaps = 3/77 (3%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESC--RPGLCGPG-KCMNTADS 397 C+ N C+N GVC + C C PGF G+ C+R C PG C G C NT S Sbjct: 159 CSANPCVNGGVCLATYPQ--IQCHCPPGFEGHACERDVNECFQDPGPCPKGTSCHNTLGS 216 Query: 398 YKCACPVTYTGKNCEVK 448 ++C CPV G CE++ Sbjct: 217 FQCLCPVGQEGPRCELR 233 Score = 63.7 bits (148), Expect = 4e-10 Identities = 31/105 (29%), Positives = 47/105 (44%), Gaps = 1/105 (0%) Frame = +2 Query: 203 ENVQNCFTCAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLCGPGK-C 379 E+V C P C N G CQ + + C+C G+GG +C+ + C C PG C Sbjct: 312 EDVDECEAQGPPHCRNGGTCQNSAGS--FHCVCVSGWGGTSCEENLDDCIAATCAPGSTC 369 Query: 380 MNTADSYKCACPVTYTGKNCEVKQLIEYPAFTGSA*LAIKPPTST 514 ++ S+ C CP TG C ++ + G A + P T + Sbjct: 370 IDRVGSFSCLCPPGRTGLLCHLEDMCLSQPCHGDAQCSTNPLTGS 414 Score = 60.9 bits (141), Expect = 3e-09 Identities = 28/74 (37%), Positives = 38/74 (51%), Gaps = 3/74 (4%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHG--YVCLCAPGFGGNNCDRIGESCRPGLC-GPGKCMNTADS 397 C P C N G CQ + ++CLC PGF G C+ ++C C G C + D+ Sbjct: 237 CPPRGCSNGGTCQLMPEKDSTFHLCLCPPGFIGPGCEVNPDNCVSHQCQNGGTCQDGLDT 296 Query: 398 YKCACPVTYTGKNC 439 Y C CP T+TG +C Sbjct: 297 YTCLCPETWTGWDC 310 Score = 59.7 bits (138), Expect = 6e-09 Identities = 28/89 (31%), Positives = 44/89 (49%), Gaps = 3/89 (3%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLC-GPGKCMNTADSYK 403 CA CLN+ C + L +G+ C+C PGF G C+ + CR C G+C + ++ Sbjct: 516 CASAPCLNHADCHDLL--NGFQCICLPGFSGTRCEEDIDECRSSPCANGGQCQDQPGAFH 573 Query: 404 CACPVTYTGKNC--EVKQLIEYPAFTGSA 484 C C + G C EV + + P G++ Sbjct: 574 CKCLPGFEGPRCQTEVDECLSDPCPVGAS 602 Score = 59.7 bits (138), Expect = 6e-09 Identities = 30/90 (33%), Positives = 43/90 (47%), Gaps = 4/90 (4%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLC-GPGKCMNTADSYK 403 C C N C + GY+C CAPG+ G NC + ++C+ C G C + Sbjct: 933 CESRPCQNGATCMAQPS--GYLCQCAPGYDGQNCSKELDACQSQPCHNHGTCTPKPGGFH 990 Query: 404 CACPVTYTGKNCE--VKQLIEYPAF-TGSA 484 CACP + G CE V + ++ P TG+A Sbjct: 991 CACPPGFVGLRCEGDVDECLDQPCHPTGTA 1020 Score = 57.6 bits (133), Expect = 3e-08 Identities = 29/93 (31%), Positives = 38/93 (40%), Gaps = 8/93 (8%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLCGP------GKCMNT 388 C C + C +CLC PG+ G C + + C GP G C+NT Sbjct: 395 CLSQPCHGDAQCSTNPLTGSTLCLCQPGYSGPTCHQDLDECLMAQQGPSPCEHGGSCLNT 454 Query: 389 ADSYKCACPVTYTGKNCEV--KQLIEYPAFTGS 481 S+ C CP YTG CE + + P GS Sbjct: 455 PGSFNCLCPPGYTGSRCEADHNECLSQPCHPGS 487 Score = 54.0 bits (124), Expect = 3e-07 Identities = 25/74 (33%), Positives = 35/74 (47%), Gaps = 1/74 (1%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLCGPG-KCMNTADSYK 403 C + C N G CQ+ + C C PGF G C + C C G C++ ++ Sbjct: 554 CRSSPCANGGQCQDQ--PGAFHCKCLPGFEGPRCQTEVDECLSDPCPVGASCLDLPGAFF 611 Query: 404 CACPVTYTGKNCEV 445 C CP +TG+ CEV Sbjct: 612 CLCPSGFTGQLCEV 625 Score = 52.8 bits (121), Expect = 7e-07 Identities = 24/73 (32%), Positives = 36/73 (49%), Gaps = 1/73 (1%) Frame = +2 Query: 233 PNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLCGPGK-CMNTADSYKCA 409 P+ C + G C T + CLC PG+ G+ C+ C C PG C++ ++ C Sbjct: 442 PSPCEHGGSCLN--TPGSFNCLCPPGYTGSRCEADHNECLSQPCHPGSTCLDLLATFHCL 499 Query: 410 CPVTYTGKNCEVK 448 CP G+ CEV+ Sbjct: 500 CPPGLEGQLCEVE 512 Score = 52.8 bits (121), Expect = 7e-07 Identities = 26/87 (29%), Positives = 35/87 (40%), Gaps = 3/87 (3%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLC-GPGKCMNTADSYK 403 C C + G C + GY C C G+ G C +C G C G C + Y Sbjct: 694 CISAPCAHGGTCYPQPS--GYNCTCPTGYTGPTCSEEMTACHSGPCLNGGSCNPSPGGYY 751 Query: 404 CACPVTYTGKNCEVK--QLIEYPAFTG 478 C CP ++TG C+ + P F G Sbjct: 752 CTCPPSHTGPQCQTSTDYCVSAPCFNG 778 Score = 51.2 bits (117), Expect = 2e-06 Identities = 26/76 (34%), Positives = 35/76 (46%), Gaps = 4/76 (5%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCR---PGLC-GPGKCMNTAD 394 C + C N G CQ+ L Y CLC + G +C + C P C G C N+A Sbjct: 279 CVSHQCQNGGTCQDGLDT--YTCLCPETWTGWDCSEDVDECEAQGPPHCRNGGTCQNSAG 336 Query: 395 SYKCACPVTYTGKNCE 442 S+ C C + G +CE Sbjct: 337 SFHCVCVSGWGGTSCE 352 Score = 51.2 bits (117), Expect = 2e-06 Identities = 24/75 (32%), Positives = 31/75 (41%), Gaps = 1/75 (1%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLC-GPGKCMNTADSYK 403 C CLN G C + GY C C P G C + C C G C+N ++ Sbjct: 732 CHSGPCLNGGSCNPS--PGGYYCTCPPSHTGPQCQTSTDYCVSAPCFNGGTCVNRPGTFS 789 Query: 404 CACPVTYTGKNCEVK 448 C C + + G CE K Sbjct: 790 CLCAMGFQGPRCEGK 804 Score = 50.4 bits (115), Expect = 4e-06 Identities = 25/69 (36%), Positives = 31/69 (44%), Gaps = 1/69 (1%) Frame = +2 Query: 236 NLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLCGPG-KCMNTADSYKCAC 412 +LC N G+C ++ Y C C PGF G+ C C C G CM Y C C Sbjct: 898 SLCHNGGLCVDS--GPSYFCHCPPGFQGSLCQDHVNPCESRPCQNGATCMAQPSGYLCQC 955 Query: 413 PVTYTGKNC 439 Y G+NC Sbjct: 956 APGYDGQNC 964 Score = 50.0 bits (114), Expect = 5e-06 Identities = 24/74 (32%), Positives = 33/74 (44%), Gaps = 2/74 (2%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCD-RIGESCRPGLC-GPGKCMNTADSY 400 C C N G C + CLCA GF G C+ ++ SC C C ++ Sbjct: 770 CVSAPCFNGGTCVNR--PGTFSCLCAMGFQGPRCEGKLRPSCADSPCRNRATCQDSPQGP 827 Query: 401 KCACPVTYTGKNCE 442 +C CP YTG +C+ Sbjct: 828 RCLCPTGYTGGSCQ 841 Score = 50.0 bits (114), Expect = 5e-06 Identities = 23/75 (30%), Positives = 35/75 (46%), Gaps = 1/75 (1%) Frame = +2 Query: 224 TCAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLCGPGK-CMNTADSY 400 +CA + C N CQ++ G CLC G+ G +C + + C C C+ T S+ Sbjct: 808 SCADSPCRNRATCQDS--PQGPRCLCPTGYTGGSCQTLMDLCAQKPCPRNSHCLQTGPSF 865 Query: 401 KCACPVTYTGKNCEV 445 C C +TG C + Sbjct: 866 HCLCLQGWTGPLCNL 880 Score = 49.2 bits (112), Expect = 9e-06 Identities = 28/86 (32%), Positives = 39/86 (45%), Gaps = 7/86 (8%) Frame = +2 Query: 212 QNCF----TCAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLCGP--- 370 QNC C C N+G C G+ C C PGF G C+ + C C P Sbjct: 962 QNCSKELDACQSQPCHNHGTCTPK--PGGFHCACPPGFVGLRCEGDVDECLDQPCHPTGT 1019 Query: 371 GKCMNTADSYKCACPVTYTGKNCEVK 448 C + A+++ C C +TG+ CEV+ Sbjct: 1020 AACHSLANAFYCQCLPGHTGQWCEVE 1045 Score = 46.8 bits (106), Expect = 5e-05 Identities = 22/76 (28%), Positives = 37/76 (48%), Gaps = 4/76 (5%) Frame = +2 Query: 287 YVCLCAPGFGGNNCD-RIGESCRPGLCGP-GKC-MNTADSYKCACPVTYTGKNCEVKQLI 457 ++C C PGF G C ++ + C P C G+C + + +C+C +TG+ C+++ Sbjct: 100 FLCTCLPGFTGERCQAKLEDPCPPSFCSKRGRCHIQASGRPQCSCMPGWTGEQCQLRDFC 159 Query: 458 E-YPAFTGSA*LAIKP 502 P G LA P Sbjct: 160 SANPCVNGGVCLATYP 175 Score = 41.5 bits (93), Expect = 0.002 Identities = 24/75 (32%), Positives = 30/75 (40%), Gaps = 4/75 (5%) Frame = +2 Query: 227 CAP---NLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLCGPG-KCMNTAD 394 CAP N ++G CQ + C+C G+ G C+ C C G C Sbjct: 657 CAPPEDNCTCHHGHCQRSS------CVCDVGWTGPECEAELGGCISAPCAHGGTCYPQPS 710 Query: 395 SYKCACPVTYTGKNC 439 Y C CP YTG C Sbjct: 711 GYNCTCPTGYTGPTC 725 Score = 40.7 bits (91), Expect = 0.003 Identities = 24/74 (32%), Positives = 34/74 (45%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLCGPGKCMNTADSYKC 406 CAPNLC +C++ + CLC G G C ++C C G C ++ C Sbjct: 628 CAPNLCQPKQICKDQKDKAN--CLCPDGSPG--CAPPEDNC---TCHHGHCQRSS----C 676 Query: 407 ACPVTYTGKNCEVK 448 C V +TG CE + Sbjct: 677 VCDVGWTGPECEAE 690 Score = 39.5 bits (88), Expect = 0.007 Identities = 27/87 (31%), Positives = 34/87 (39%), Gaps = 5/87 (5%) Frame = +2 Query: 200 KENVQNCFTCAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLCGPG-- 373 + +V CF P C C L + CLC G G C+ C P C G Sbjct: 191 ERDVNECFQ-DPGPCPKGTSCHNTLGS--FQCLCPVGQEGPRCELRAGPCPPRGCSNGGT 247 Query: 374 -KCMNTADS--YKCACPVTYTGKNCEV 445 + M DS + C CP + G CEV Sbjct: 248 CQLMPEKDSTFHLCLCPPGFIGPGCEV 274 Score = 39.1 bits (87), Expect = 0.010 Identities = 19/73 (26%), Positives = 28/73 (38%), Gaps = 1/73 (1%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLC-GPGKCMNTADSYK 403 C C C + L + CLC PG G C+ C C C + + ++ Sbjct: 478 CLSQPCHPGSTCLDLLAT--FHCLCPPGLEGQLCEVETNECASAPCLNHADCHDLLNGFQ 535 Query: 404 CACPVTYTGKNCE 442 C C ++G CE Sbjct: 536 CICLPGFSGTRCE 548 Score = 38.7 bits (86), Expect = 0.013 Identities = 24/78 (30%), Positives = 31/78 (39%), Gaps = 7/78 (8%) Frame = +2 Query: 227 CAPNLCLNNGVCQE-ALTEHGYVCLCAPGFGGNNCDRIGESC------RPGLCGPGKCMN 385 C C + G C+ A + G++C C GF G C SC GLC P Sbjct: 1049 CHSQPCFHGGTCEATAGSPLGFICHCPKGFEGPTCSHRAPSCGFHHCHHGGLCLPSP--K 1106 Query: 386 TADSYKCACPVTYTGKNC 439 +CAC Y G +C Sbjct: 1107 PGFPPRCACLSGYGGPDC 1124 Score = 37.9 bits (84), Expect = 0.022 Identities = 27/87 (31%), Positives = 33/87 (37%), Gaps = 15/87 (17%) Frame = +2 Query: 233 PNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCD-----------RIGESCR---PGLCG- 367 P C N G C G C CAPGF G C + G SC+ P G Sbjct: 31 PEPCANGGTCLSLSLGQG-TCQCAPGFLGETCQFPDPCQNAQLCQNGGSCQALLPAPLGL 89 Query: 368 PGKCMNTADSYKCACPVTYTGKNCEVK 448 P S+ C C +TG+ C+ K Sbjct: 90 PSSPSPLTPSFLCTCLPGFTGERCQAK 116 Score = 37.9 bits (84), Expect = 0.022 Identities = 25/83 (30%), Positives = 35/83 (42%), Gaps = 11/83 (13%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPG----------LC-GPG 373 CA C N C + T + CLC G+ G C+ SC+ LC G Sbjct: 847 CAQKPCPRNSHCLQ--TGPSFHCLCLQGWTGPLCNLPLSSCQKAALSQGIDVSSLCHNGG 904 Query: 374 KCMNTADSYKCACPVTYTGKNCE 442 C+++ SY C CP + G C+ Sbjct: 905 LCVDSGPSYFCHCPPGFQGSLCQ 927 Score = 33.9 bits (74), Expect = 0.36 Identities = 21/75 (28%), Positives = 27/75 (36%), Gaps = 4/75 (5%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLC-GPGKCMNTADS-- 397 C C G + + C C PG G C+ + C C G C TA S Sbjct: 1009 CLDQPCHPTGTAACHSLANAFYCQCLPGHTGQWCEVEIDPCHSQPCFHGGTCEATAGSPL 1068 Query: 398 -YKCACPVTYTGKNC 439 + C CP + G C Sbjct: 1069 GFICHCPKGFEGPTC 1083 Score = 33.1 bits (72), Expect = 0.63 Identities = 18/51 (35%), Positives = 21/51 (41%), Gaps = 2/51 (3%) Frame = +2 Query: 233 PNLCLNNGVCQEA--LTEHGYVCLCAPGFGGNNCDRIGESCRPGLCGPGKC 379 P+ CL NG C E L G+ C C G C + G G G G C Sbjct: 1136 PSPCLYNGSCSETTGLGGPGFRCSCPHSSPGPRCQKPGAKGCEGRSGDGAC 1186 Score = 31.9 bits (69), Expect = 1.5 Identities = 23/86 (26%), Positives = 38/86 (44%), Gaps = 13/86 (15%) Frame = +2 Query: 224 TCAPNLCLNNGVCQEALTEHGYV--CLCAPGFGGNNCDRIGESCRPGLCGP-------GK 376 +C + C + G+C + + G+ C C G+GG +C + G CGP G Sbjct: 1089 SCGFHHCHHGGLCLPS-PKPGFPPRCACLSGYGGPDC--LTPPAPKG-CGPPSPCLYNGS 1144 Query: 377 CMNTAD----SYKCACPVTYTGKNCE 442 C T ++C+CP + G C+ Sbjct: 1145 CSETTGLGGPGFRCSCPHSSPGPRCQ 1170 >U26555-1|AAA67565.1| 1642|Homo sapiens versican V2 core protein precursor protein. Length = 1642 Score = 64.1 bits (149), Expect = 3e-10 Identities = 29/82 (35%), Positives = 41/82 (50%), Gaps = 1/82 (1%) Frame = +2 Query: 200 KENVQNCFTCAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLCGPG-K 376 +EN C N CLN G C TE YVC C PG+ G+ C+ + C C G Sbjct: 1330 RENKTGPDRCKMNPCLNGGTCYP--TETSYVCTCVPGYSGDQCELDFDECHSNPCRNGAT 1387 Query: 377 CMNTADSYKCACPVTYTGKNCE 442 C++ ++++C C +Y G CE Sbjct: 1388 CVDGFNTFRCLCLPSYVGALCE 1409 Score = 31.9 bits (69), Expect = 1.5 Identities = 14/44 (31%), Positives = 20/44 (45%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPG 358 C N C N C + + CLC P + G C++ E+C G Sbjct: 1377 CHSNPCRNGATCVDGFNT--FRCLCLPSYVGALCEQDTETCDYG 1418 Score = 30.7 bits (66), Expect = 3.4 Identities = 13/36 (36%), Positives = 17/36 (47%), Gaps = 1/36 (2%) Frame = +2 Query: 341 ESCRPGLC-GPGKCMNTADSYKCACPVTYTGKNCEV 445 + C+ C G C T SY C C Y+G CE+ Sbjct: 1337 DRCKMNPCLNGGTCYPTETSYVCTCVPGYSGDQCEL 1372 >AL662830-9|CAI17543.1| 2005|Homo sapiens Notch homolog 4 (Drosophila) protein. Length = 2005 Score = 64.1 bits (149), Expect = 3e-10 Identities = 31/77 (40%), Positives = 40/77 (51%), Gaps = 3/77 (3%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESC--RPGLCGPG-KCMNTADS 397 C+ N C+N GVC + C C PGF G+ C+R C PG C G C NT S Sbjct: 162 CSANPCVNGGVCLATYPQ--IQCHCPPGFEGHACERDVNECFQDPGPCPKGTSCHNTLGS 219 Query: 398 YKCACPVTYTGKNCEVK 448 ++C CPV G CE++ Sbjct: 220 FQCLCPVGQEGPRCELR 236 Score = 63.7 bits (148), Expect = 4e-10 Identities = 31/105 (29%), Positives = 47/105 (44%), Gaps = 1/105 (0%) Frame = +2 Query: 203 ENVQNCFTCAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLCGPGK-C 379 E+V C P C N G CQ + + C+C G+GG +C+ + C C PG C Sbjct: 315 EDVDECEAQGPPHCRNGGTCQNSAGS--FHCVCVSGWGGTSCEENLDDCIAATCAPGSTC 372 Query: 380 MNTADSYKCACPVTYTGKNCEVKQLIEYPAFTGSA*LAIKPPTST 514 ++ S+ C CP TG C ++ + G A + P T + Sbjct: 373 IDRVGSFSCLCPPGRTGLLCHLEDMCLSQPCHGDAQCSTNPLTGS 417 Score = 61.3 bits (142), Expect = 2e-09 Identities = 28/74 (37%), Positives = 39/74 (52%), Gaps = 3/74 (4%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHG--YVCLCAPGFGGNNCDRIGESCRPGLC-GPGKCMNTADS 397 C P C N G CQ + ++CLC PGF G +C+ ++C C G C + D+ Sbjct: 240 CPPRGCSNGGTCQLMPEKDSTFHLCLCPPGFIGPDCEVNPDNCVSHQCQNGGTCQDGLDT 299 Query: 398 YKCACPVTYTGKNC 439 Y C CP T+TG +C Sbjct: 300 YTCLCPETWTGWDC 313 Score = 59.7 bits (138), Expect = 6e-09 Identities = 28/89 (31%), Positives = 44/89 (49%), Gaps = 3/89 (3%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLC-GPGKCMNTADSYK 403 CA CLN+ C + L +G+ C+C PGF G C+ + CR C G+C + ++ Sbjct: 519 CASAPCLNHADCHDLL--NGFQCICLPGFSGTRCEEDIDECRSSPCANGGQCQDQPGAFH 576 Query: 404 CACPVTYTGKNC--EVKQLIEYPAFTGSA 484 C C + G C EV + + P G++ Sbjct: 577 CKCLPGFEGPRCQTEVDECLSDPCPVGAS 605 Score = 59.7 bits (138), Expect = 6e-09 Identities = 30/90 (33%), Positives = 43/90 (47%), Gaps = 4/90 (4%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLC-GPGKCMNTADSYK 403 C C N C + GY+C CAPG+ G NC + ++C+ C G C + Sbjct: 936 CESRPCQNGATCMAQPS--GYLCQCAPGYDGQNCSKELDACQSQPCHNHGTCTPKPGGFH 993 Query: 404 CACPVTYTGKNCE--VKQLIEYPAF-TGSA 484 CACP + G CE V + ++ P TG+A Sbjct: 994 CACPPGFVGLRCEGDVDECLDQPCHPTGTA 1023 Score = 57.6 bits (133), Expect = 3e-08 Identities = 29/93 (31%), Positives = 38/93 (40%), Gaps = 8/93 (8%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLCGP------GKCMNT 388 C C + C +CLC PG+ G C + + C GP G C+NT Sbjct: 398 CLSQPCHGDAQCSTNPLTGSTLCLCQPGYSGPTCHQDLDECLMAQQGPSPCEHGGSCLNT 457 Query: 389 ADSYKCACPVTYTGKNCEV--KQLIEYPAFTGS 481 S+ C CP YTG CE + + P GS Sbjct: 458 PGSFNCLCPPGYTGSRCEADHNECLSQPCHPGS 490 Score = 54.0 bits (124), Expect = 3e-07 Identities = 25/74 (33%), Positives = 35/74 (47%), Gaps = 1/74 (1%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLCGPG-KCMNTADSYK 403 C + C N G CQ+ + C C PGF G C + C C G C++ ++ Sbjct: 557 CRSSPCANGGQCQDQ--PGAFHCKCLPGFEGPRCQTEVDECLSDPCPVGASCLDLPGAFF 614 Query: 404 CACPVTYTGKNCEV 445 C CP +TG+ CEV Sbjct: 615 CLCPSGFTGQLCEV 628 Score = 52.8 bits (121), Expect = 7e-07 Identities = 24/73 (32%), Positives = 36/73 (49%), Gaps = 1/73 (1%) Frame = +2 Query: 233 PNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLCGPGK-CMNTADSYKCA 409 P+ C + G C T + CLC PG+ G+ C+ C C PG C++ ++ C Sbjct: 445 PSPCEHGGSCLN--TPGSFNCLCPPGYTGSRCEADHNECLSQPCHPGSTCLDLLATFHCL 502 Query: 410 CPVTYTGKNCEVK 448 CP G+ CEV+ Sbjct: 503 CPPGLEGQLCEVE 515 Score = 52.8 bits (121), Expect = 7e-07 Identities = 26/87 (29%), Positives = 35/87 (40%), Gaps = 3/87 (3%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLC-GPGKCMNTADSYK 403 C C + G C + GY C C G+ G C +C G C G C + Y Sbjct: 697 CISAPCAHGGTCYPQPS--GYNCTCPTGYTGPTCSEEMTACHSGPCLNGGSCNPSPGGYY 754 Query: 404 CACPVTYTGKNCEVK--QLIEYPAFTG 478 C CP ++TG C+ + P F G Sbjct: 755 CTCPPSHTGPQCQTSTDYCVSAPCFNG 781 Score = 51.2 bits (117), Expect = 2e-06 Identities = 26/76 (34%), Positives = 35/76 (46%), Gaps = 4/76 (5%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCR---PGLC-GPGKCMNTAD 394 C + C N G CQ+ L Y CLC + G +C + C P C G C N+A Sbjct: 282 CVSHQCQNGGTCQDGLDT--YTCLCPETWTGWDCSEDVDECEAQGPPHCRNGGTCQNSAG 339 Query: 395 SYKCACPVTYTGKNCE 442 S+ C C + G +CE Sbjct: 340 SFHCVCVSGWGGTSCE 355 Score = 51.2 bits (117), Expect = 2e-06 Identities = 24/75 (32%), Positives = 31/75 (41%), Gaps = 1/75 (1%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLC-GPGKCMNTADSYK 403 C CLN G C + GY C C P G C + C C G C+N ++ Sbjct: 735 CHSGPCLNGGSCNPS--PGGYYCTCPPSHTGPQCQTSTDYCVSAPCFNGGTCVNRPGTFS 792 Query: 404 CACPVTYTGKNCEVK 448 C C + + G CE K Sbjct: 793 CLCAMGFQGPRCEGK 807 Score = 50.4 bits (115), Expect = 4e-06 Identities = 25/69 (36%), Positives = 31/69 (44%), Gaps = 1/69 (1%) Frame = +2 Query: 236 NLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLCGPG-KCMNTADSYKCAC 412 +LC N G+C ++ Y C C PGF G+ C C C G CM Y C C Sbjct: 901 SLCHNGGLCVDS--GPSYFCHCPPGFQGSLCQDHVNPCESRPCQNGATCMAQPSGYLCQC 958 Query: 413 PVTYTGKNC 439 Y G+NC Sbjct: 959 APGYDGQNC 967 Score = 50.0 bits (114), Expect = 5e-06 Identities = 24/74 (32%), Positives = 33/74 (44%), Gaps = 2/74 (2%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCD-RIGESCRPGLC-GPGKCMNTADSY 400 C C N G C + CLCA GF G C+ ++ SC C C ++ Sbjct: 773 CVSAPCFNGGTCVNR--PGTFSCLCAMGFQGPRCEGKLRPSCADSPCRNRATCQDSPQGP 830 Query: 401 KCACPVTYTGKNCE 442 +C CP YTG +C+ Sbjct: 831 RCLCPTGYTGGSCQ 844 Score = 50.0 bits (114), Expect = 5e-06 Identities = 23/75 (30%), Positives = 35/75 (46%), Gaps = 1/75 (1%) Frame = +2 Query: 224 TCAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLCGPGK-CMNTADSY 400 +CA + C N CQ++ G CLC G+ G +C + + C C C+ T S+ Sbjct: 811 SCADSPCRNRATCQDS--PQGPRCLCPTGYTGGSCQTLMDLCAQKPCPRNSHCLQTGPSF 868 Query: 401 KCACPVTYTGKNCEV 445 C C +TG C + Sbjct: 869 HCLCLQGWTGPLCNL 883 Score = 49.2 bits (112), Expect = 9e-06 Identities = 28/86 (32%), Positives = 39/86 (45%), Gaps = 7/86 (8%) Frame = +2 Query: 212 QNCF----TCAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLCGP--- 370 QNC C C N+G C G+ C C PGF G C+ + C C P Sbjct: 965 QNCSKELDACQSQPCHNHGTCTPK--PGGFHCACPPGFVGLRCEGDVDECLDQPCHPTGT 1022 Query: 371 GKCMNTADSYKCACPVTYTGKNCEVK 448 C + A+++ C C +TG+ CEV+ Sbjct: 1023 AACHSLANAFYCQCLPGHTGQWCEVE 1048 Score = 46.4 bits (105), Expect = 6e-05 Identities = 22/76 (28%), Positives = 37/76 (48%), Gaps = 4/76 (5%) Frame = +2 Query: 287 YVCLCAPGFGGNNCD-RIGESCRPGLCGP-GKC-MNTADSYKCACPVTYTGKNCEVKQLI 457 ++C C PGF G C ++ + C P C G+C + + +C+C +TG+ C+++ Sbjct: 103 FLCTCLPGFTGERCQAQLEDPCPPSFCSKRGRCHIQASGRPQCSCMPGWTGEQCQLRDFC 162 Query: 458 E-YPAFTGSA*LAIKP 502 P G LA P Sbjct: 163 SANPCVNGGVCLATYP 178 Score = 41.5 bits (93), Expect = 0.002 Identities = 24/75 (32%), Positives = 30/75 (40%), Gaps = 4/75 (5%) Frame = +2 Query: 227 CAP---NLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLCGPG-KCMNTAD 394 CAP N ++G CQ + C+C G+ G C+ C C G C Sbjct: 660 CAPPEDNCTCHHGHCQRSS------CVCDVGWTGPECEAELGGCISAPCAHGGTCYPQPS 713 Query: 395 SYKCACPVTYTGKNC 439 Y C CP YTG C Sbjct: 714 GYNCTCPTGYTGPTC 728 Score = 40.7 bits (91), Expect = 0.003 Identities = 24/74 (32%), Positives = 34/74 (45%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLCGPGKCMNTADSYKC 406 CAPNLC +C++ + CLC G G C ++C C G C ++ C Sbjct: 631 CAPNLCQPKQICKDQKDKAN--CLCPDGSPG--CAPPEDNC---TCHHGHCQRSS----C 679 Query: 407 ACPVTYTGKNCEVK 448 C V +TG CE + Sbjct: 680 VCDVGWTGPECEAE 693 Score = 39.9 bits (89), Expect = 0.006 Identities = 27/87 (31%), Positives = 35/87 (40%), Gaps = 5/87 (5%) Frame = +2 Query: 200 KENVQNCFTCAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLCGPG-- 373 + +V CF P C C L + CLC G G C+ C P C G Sbjct: 194 ERDVNECFQ-DPGPCPKGTSCHNTLGS--FQCLCPVGQEGPRCELRAGPCPPRGCSNGGT 250 Query: 374 -KCMNTADS--YKCACPVTYTGKNCEV 445 + M DS + C CP + G +CEV Sbjct: 251 CQLMPEKDSTFHLCLCPPGFIGPDCEV 277 Score = 39.1 bits (87), Expect = 0.010 Identities = 19/73 (26%), Positives = 28/73 (38%), Gaps = 1/73 (1%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLC-GPGKCMNTADSYK 403 C C C + L + CLC PG G C+ C C C + + ++ Sbjct: 481 CLSQPCHPGSTCLDLLAT--FHCLCPPGLEGQLCEVETNECASAPCLNHADCHDLLNGFQ 538 Query: 404 CACPVTYTGKNCE 442 C C ++G CE Sbjct: 539 CICLPGFSGTRCE 551 Score = 38.7 bits (86), Expect = 0.013 Identities = 24/78 (30%), Positives = 31/78 (39%), Gaps = 7/78 (8%) Frame = +2 Query: 227 CAPNLCLNNGVCQE-ALTEHGYVCLCAPGFGGNNCDRIGESC------RPGLCGPGKCMN 385 C C + G C+ A + G++C C GF G C SC GLC P Sbjct: 1052 CHSQPCFHGGTCEATAGSPLGFICHCPKGFEGPTCSHRAPSCGFHHCHHGGLCLPSP--K 1109 Query: 386 TADSYKCACPVTYTGKNC 439 +CAC Y G +C Sbjct: 1110 PGFPPRCACLSGYGGPDC 1127 Score = 37.9 bits (84), Expect = 0.022 Identities = 25/83 (30%), Positives = 35/83 (42%), Gaps = 11/83 (13%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPG----------LC-GPG 373 CA C N C + T + CLC G+ G C+ SC+ LC G Sbjct: 850 CAQKPCPRNSHCLQ--TGPSFHCLCLQGWTGPLCNLPLSSCQKAALSQGIDVSSLCHNGG 907 Query: 374 KCMNTADSYKCACPVTYTGKNCE 442 C+++ SY C CP + G C+ Sbjct: 908 LCVDSGPSYFCHCPPGFQGSLCQ 930 Score = 36.3 bits (80), Expect = 0.068 Identities = 26/87 (29%), Positives = 33/87 (37%), Gaps = 15/87 (17%) Frame = +2 Query: 233 PNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCD-----------RIGESCR---PGLCG- 367 P C N G C G C CAPGF G C + G SC+ P G Sbjct: 34 PEPCANGGTCLSLSLGQG-TCQCAPGFLGETCQFPDPCQNAQLCQNGGSCQALLPAPLGL 92 Query: 368 PGKCMNTADSYKCACPVTYTGKNCEVK 448 P S+ C C +TG+ C+ + Sbjct: 93 PSSPSPLTPSFLCTCLPGFTGERCQAQ 119 Score = 33.9 bits (74), Expect = 0.36 Identities = 21/75 (28%), Positives = 27/75 (36%), Gaps = 4/75 (5%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLC-GPGKCMNTADS-- 397 C C G + + C C PG G C+ + C C G C TA S Sbjct: 1012 CLDQPCHPTGTAACHSLANAFYCQCLPGHTGQWCEVEIDPCHSQPCFHGGTCEATAGSPL 1071 Query: 398 -YKCACPVTYTGKNC 439 + C CP + G C Sbjct: 1072 GFICHCPKGFEGPTC 1086 Score = 33.1 bits (72), Expect = 0.63 Identities = 18/51 (35%), Positives = 21/51 (41%), Gaps = 2/51 (3%) Frame = +2 Query: 233 PNLCLNNGVCQEA--LTEHGYVCLCAPGFGGNNCDRIGESCRPGLCGPGKC 379 P+ CL NG C E L G+ C C G C + G G G G C Sbjct: 1139 PSPCLYNGSCSETTGLGGPGFRCSCPHSSPGPRCQKPGAKGCEGRSGDGAC 1189 Score = 31.9 bits (69), Expect = 1.5 Identities = 23/86 (26%), Positives = 38/86 (44%), Gaps = 13/86 (15%) Frame = +2 Query: 224 TCAPNLCLNNGVCQEALTEHGYV--CLCAPGFGGNNCDRIGESCRPGLCGP-------GK 376 +C + C + G+C + + G+ C C G+GG +C + G CGP G Sbjct: 1092 SCGFHHCHHGGLCLPS-PKPGFPPRCACLSGYGGPDC--LTPPAPKG-CGPPSPCLYNGS 1147 Query: 377 CMNTAD----SYKCACPVTYTGKNCE 442 C T ++C+CP + G C+ Sbjct: 1148 CSETTGLGGPGFRCSCPHSSPGPRCQ 1173 >AB023961-1|BAB20317.1| 502|Homo sapiens notch4 protein. Length = 502 Score = 64.1 bits (149), Expect = 3e-10 Identities = 31/77 (40%), Positives = 40/77 (51%), Gaps = 3/77 (3%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESC--RPGLCGPG-KCMNTADS 397 C+ N C+N GVC + C C PGF G+ C+R C PG C G C NT S Sbjct: 159 CSANPCVNGGVCLATYPQ--IQCHCPPGFEGHACERDVNECFQDPGPCPKGTSCHNTLGS 216 Query: 398 YKCACPVTYTGKNCEVK 448 ++C CPV G CE++ Sbjct: 217 FQCLCPVGQEGPRCELR 233 Score = 63.7 bits (148), Expect = 4e-10 Identities = 31/105 (29%), Positives = 47/105 (44%), Gaps = 1/105 (0%) Frame = +2 Query: 203 ENVQNCFTCAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLCGPGK-C 379 E+V C P C N G CQ + + C+C G+GG +C+ + C C PG C Sbjct: 312 EDVDECEAQGPPHCRNGGTCQNSAGS--FHCVCVSGWGGTSCEENLDDCIAATCAPGSTC 369 Query: 380 MNTADSYKCACPVTYTGKNCEVKQLIEYPAFTGSA*LAIKPPTST 514 ++ S+ C CP TG C ++ + G A + P T + Sbjct: 370 IDRVGSFSCLCPPGRTGLLCHLEDMCLSQPCHGDAQCSTNPLTGS 414 Score = 60.9 bits (141), Expect = 3e-09 Identities = 28/74 (37%), Positives = 38/74 (51%), Gaps = 3/74 (4%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHG--YVCLCAPGFGGNNCDRIGESCRPGLC-GPGKCMNTADS 397 C P C N G CQ + ++CLC PGF G C+ ++C C G C + D+ Sbjct: 237 CPPRGCSNGGTCQLMPEKDSTFHLCLCPPGFIGPGCEVNPDNCVSHQCQNGGTCQDGLDT 296 Query: 398 YKCACPVTYTGKNC 439 Y C CP T+TG +C Sbjct: 297 YTCLCPETWTGWDC 310 Score = 57.6 bits (133), Expect = 3e-08 Identities = 29/93 (31%), Positives = 38/93 (40%), Gaps = 8/93 (8%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLCGP------GKCMNT 388 C C + C +CLC PG+ G C + + C GP G C+NT Sbjct: 395 CLSQPCHGDAQCSTNPLTGSTLCLCQPGYSGPTCHQDLDECLMAQQGPSPCEHGGSCLNT 454 Query: 389 ADSYKCACPVTYTGKNCEV--KQLIEYPAFTGS 481 S+ C CP YTG CE + + P GS Sbjct: 455 PGSFNCLCPPGYTGSRCEADHNECLSQPCHPGS 487 Score = 51.2 bits (117), Expect = 2e-06 Identities = 26/76 (34%), Positives = 35/76 (46%), Gaps = 4/76 (5%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCR---PGLC-GPGKCMNTAD 394 C + C N G CQ+ L Y CLC + G +C + C P C G C N+A Sbjct: 279 CVSHQCQNGGTCQDGLDT--YTCLCPETWTGWDCSEDVDECEAQGPPHCRNGGTCQNSAG 336 Query: 395 SYKCACPVTYTGKNCE 442 S+ C C + G +CE Sbjct: 337 SFHCVCVSGWGGTSCE 352 Score = 46.8 bits (106), Expect = 5e-05 Identities = 22/76 (28%), Positives = 37/76 (48%), Gaps = 4/76 (5%) Frame = +2 Query: 287 YVCLCAPGFGGNNCD-RIGESCRPGLCGP-GKC-MNTADSYKCACPVTYTGKNCEVKQLI 457 ++C C PGF G C ++ + C P C G+C + + +C+C +TG+ C+++ Sbjct: 100 FLCTCLPGFTGERCQAKLEDPCPPSFCSKRGRCHIQASGRPQCSCMPGWTGEQCQLRDFC 159 Query: 458 E-YPAFTGSA*LAIKP 502 P G LA P Sbjct: 160 SANPCVNGGVCLATYP 175 Score = 39.5 bits (88), Expect = 0.007 Identities = 27/87 (31%), Positives = 34/87 (39%), Gaps = 5/87 (5%) Frame = +2 Query: 200 KENVQNCFTCAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLCGPG-- 373 + +V CF P C C L + CLC G G C+ C P C G Sbjct: 191 ERDVNECFQ-DPGPCPKGTSCHNTLGS--FQCLCPVGQEGPRCELRAGPCPPRGCSNGGT 247 Query: 374 -KCMNTADS--YKCACPVTYTGKNCEV 445 + M DS + C CP + G CEV Sbjct: 248 CQLMPEKDSTFHLCLCPPGFIGPGCEV 274 Score = 37.9 bits (84), Expect = 0.022 Identities = 27/87 (31%), Positives = 33/87 (37%), Gaps = 15/87 (17%) Frame = +2 Query: 233 PNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCD-----------RIGESCR---PGLCG- 367 P C N G C G C CAPGF G C + G SC+ P G Sbjct: 31 PEPCANGGTCLSLSLGQG-TCQCAPGFLGETCQFPDPCQNAQLCQNGGSCQALLPAPLGL 89 Query: 368 PGKCMNTADSYKCACPVTYTGKNCEVK 448 P S+ C C +TG+ C+ K Sbjct: 90 PSSPSPLTPSFLCTCLPGFTGERCQAK 116 >AL513325-3|CAM17208.1| 1294|Homo sapiens crumbs homolog 1 (Drosophila) protein. Length = 1294 Score = 63.7 bits (148), Expect = 4e-10 Identities = 29/77 (37%), Positives = 37/77 (48%), Gaps = 4/77 (5%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLC-GPGKCMNTADSYK 403 CA + C N VCQ+ + GY C C PG+ G +CD + C C C+N Y Sbjct: 152 CASSPCQNGAVCQDGID--GYSCFCVPGYQGRHCDLEVDECASDPCKNEATCLNEIGRYT 209 Query: 404 CACPVT---YTGKNCEV 445 C CP YTG CE+ Sbjct: 210 CICPHNYSGYTGAQCEI 226 Score = 58.8 bits (136), Expect = 1e-08 Identities = 26/73 (35%), Positives = 36/73 (49%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLCGPGKCMNTADSYKC 406 C N CL+ G C++ + Y C C G+ G +C+ + C C G C + +Y C Sbjct: 1031 CNSNPCLHGGNCEDIYSS--YHCSCPLGWSGKHCELNIDECFSNPCIHGNCSDRVAAYHC 1088 Query: 407 ACPVTYTGKNCEV 445 C YTG NCEV Sbjct: 1089 TCEPGYTGVNCEV 1101 Score = 56.4 bits (130), Expect = 6e-08 Identities = 25/69 (36%), Positives = 35/69 (50%), Gaps = 1/69 (1%) Frame = +2 Query: 242 CLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLC-GPGKCMNTADSYKCACPV 418 C N G C E TE C+C PGF G C++ + C C G C + + ++C C V Sbjct: 1156 CYNGGNCTEFQTE--LKCMCRPGFTGEWCEKDIDECASDPCVNGGLCQDLLNKFQCLCDV 1213 Query: 419 TYTGKNCEV 445 + G+ CEV Sbjct: 1214 AFAGERCEV 1222 Score = 53.6 bits (123), Expect = 4e-07 Identities = 27/84 (32%), Positives = 43/84 (51%), Gaps = 1/84 (1%) Frame = +2 Query: 206 NVQNCFTCAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLCGPG-KCM 382 N+ CF+ N C++ G C + + Y C C PG+ G NC+ ++C+ C G C+ Sbjct: 1065 NIDECFS---NPCIH-GNCSDRVA--AYHCTCEPGYTGVNCEVDIDNCQSHQCANGATCI 1118 Query: 383 NTADSYKCACPVTYTGKNCEVKQL 454 + + Y C C +TGK C +L Sbjct: 1119 SHTNGYSCLCFGNFTGKFCRQSRL 1142 Score = 52.8 bits (121), Expect = 7e-07 Identities = 23/74 (31%), Positives = 31/74 (41%), Gaps = 1/74 (1%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLCGPGKCMNTADSYK- 403 C N C + C E ++C C PG+ G C+ SC C G + Y Sbjct: 74 CFSNPCQGSATCVNTPGERSFLCKCPPGYSGTICETTIGSCGKNSCQHGGICHQDPIYPV 133 Query: 404 CACPVTYTGKNCEV 445 C CP Y G+ CE+ Sbjct: 134 CICPAGYAGRFCEI 147 Score = 51.6 bits (118), Expect = 2e-06 Identities = 22/76 (28%), Positives = 36/76 (47%), Gaps = 1/76 (1%) Frame = +2 Query: 224 TCAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLCGPGK-CMNTADSY 400 +C N C + G+C + VC+C G+ G C+ + C C G C + D Y Sbjct: 113 SCGKNSCQHGGICHQDPIYP--VCICPAGYAGRFCEIDHDECASSPCQNGAVCQDGIDGY 170 Query: 401 KCACPVTYTGKNCEVK 448 C C Y G++C+++ Sbjct: 171 SCFCVPGYQGRHCDLE 186 Score = 47.2 bits (107), Expect = 4e-05 Identities = 19/45 (42%), Positives = 23/45 (51%), Gaps = 1/45 (2%) Frame = +2 Query: 284 GYVCLCAPGFGGNNCDRIGESCRPGLC-GPGKCMNTADSYKCACP 415 GYVC+C PGF G +C+ C C G C N +Y C CP Sbjct: 268 GYVCICQPGFTGIHCEEDVNECSSNPCQNGGTCENLPGNYTCHCP 312 Score = 46.8 bits (106), Expect = 5e-05 Identities = 24/80 (30%), Positives = 35/80 (43%), Gaps = 3/80 (3%) Frame = +2 Query: 212 QNCFTCAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLC-GPGKCMNT 388 +N C N C NN C++ ++ C +CD + + C C G C+NT Sbjct: 29 KNNTRCLSNSCQNNSTCKDFSKDNDCSCSDTANNLDKDCDNMKDPCFSNPCQGSATCVNT 88 Query: 389 AD--SYKCACPVTYTGKNCE 442 S+ C CP Y+G CE Sbjct: 89 PGERSFLCKCPPGYSGTICE 108 Score = 42.7 bits (96), Expect = 8e-04 Identities = 38/151 (25%), Positives = 61/151 (40%), Gaps = 12/151 (7%) Frame = +2 Query: 29 SPDQWTVLELNQPLYIGGVPDFDQLPIDLAGASGFVGCISMLILGNEE-------KNIMA 187 S W + E +YIGG+PD + ++ F GCI + L N+ N + Sbjct: 706 SASTWKI-EKGDVIYIGGLPDKQETELN---GGFFKGCIQDVRLNNQNLEFFPNPTNNAS 761 Query: 188 LALEKENV-QNCF---TCAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRP 355 L NV Q C +C N C N GVC + + C C G C+ + + C Sbjct: 762 LNPVLVNVTQGCAGDNSCKSNPCHNGGVCHSRWDD--FSCSCPALTSGKACEEV-QWCGF 818 Query: 356 GLCGPG-KCMNTADSYKCACPVTYTGKNCEV 445 C G +C ++C + G++ ++ Sbjct: 819 SPCPHGAQCQPVLQGFECIANAVFNGQSGQI 849 Score = 40.7 bits (91), Expect = 0.003 Identities = 24/88 (27%), Positives = 35/88 (39%), Gaps = 9/88 (10%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVC----LCAPGFGGNNCDRIGESCRPGLC-GPGKCM--- 382 C+ N C N G C+ + C L +GG +C I C C G C+ Sbjct: 289 CSSNPCQNGGTCENLPGNYTCHCPFDNLSRTFYGGRDCSDILLGCTHQQCLNNGTCIPHF 348 Query: 383 -NTADSYKCACPVTYTGKNCEVKQLIEY 463 + + C CP YTG CE+ + + Sbjct: 349 QDGQHGFSCLCPSGYTGSLCEIATTLSF 376 Score = 37.1 bits (82), Expect = 0.039 Identities = 14/35 (40%), Positives = 21/35 (60%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCD 331 CA + C+N G+CQ+ L + + CLC F G C+ Sbjct: 1189 CASDPCVNGGLCQDLLNK--FQCLCDVAFAGERCE 1221 Score = 33.1 bits (72), Expect = 0.63 Identities = 14/37 (37%), Positives = 19/37 (51%), Gaps = 1/37 (2%) Frame = +2 Query: 344 SCRPGLC-GPGKCMNTADSYKCACPVTYTGKNCEVKQ 451 SC+ C G C + D + C+CP +GK CE Q Sbjct: 778 SCKSNPCHNGGVCHSRWDDFSCSCPALTSGKACEEVQ 814 Score = 29.9 bits (64), Expect = 5.9 Identities = 11/23 (47%), Positives = 14/23 (60%) Frame = +2 Query: 371 GKCMNTADSYKCACPVTYTGKNC 439 G+C+N SY+C C Y G NC Sbjct: 573 GRCINLWLSYQCDCHRPYEGPNC 595 >AL139136-3|CAM21656.1| 1294|Homo sapiens crumbs homolog 1 (Drosophila) protein. Length = 1294 Score = 63.7 bits (148), Expect = 4e-10 Identities = 29/77 (37%), Positives = 37/77 (48%), Gaps = 4/77 (5%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLC-GPGKCMNTADSYK 403 CA + C N VCQ+ + GY C C PG+ G +CD + C C C+N Y Sbjct: 152 CASSPCQNGAVCQDGID--GYSCFCVPGYQGRHCDLEVDECASDPCKNEATCLNEIGRYT 209 Query: 404 CACPVT---YTGKNCEV 445 C CP YTG CE+ Sbjct: 210 CICPHNYSGYTGAQCEI 226 Score = 58.8 bits (136), Expect = 1e-08 Identities = 26/73 (35%), Positives = 36/73 (49%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLCGPGKCMNTADSYKC 406 C N CL+ G C++ + Y C C G+ G +C+ + C C G C + +Y C Sbjct: 1031 CNSNPCLHGGNCEDIYSS--YHCSCPLGWSGKHCELNIDECFSNPCIHGNCSDRVAAYHC 1088 Query: 407 ACPVTYTGKNCEV 445 C YTG NCEV Sbjct: 1089 TCEPGYTGVNCEV 1101 Score = 56.4 bits (130), Expect = 6e-08 Identities = 25/69 (36%), Positives = 35/69 (50%), Gaps = 1/69 (1%) Frame = +2 Query: 242 CLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLC-GPGKCMNTADSYKCACPV 418 C N G C E TE C+C PGF G C++ + C C G C + + ++C C V Sbjct: 1156 CYNGGNCTEFQTE--LKCMCRPGFTGEWCEKDIDECASDPCVNGGLCQDLLNKFQCLCDV 1213 Query: 419 TYTGKNCEV 445 + G+ CEV Sbjct: 1214 AFAGERCEV 1222 Score = 53.6 bits (123), Expect = 4e-07 Identities = 27/84 (32%), Positives = 43/84 (51%), Gaps = 1/84 (1%) Frame = +2 Query: 206 NVQNCFTCAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLCGPG-KCM 382 N+ CF+ N C++ G C + + Y C C PG+ G NC+ ++C+ C G C+ Sbjct: 1065 NIDECFS---NPCIH-GNCSDRVA--AYHCTCEPGYTGVNCEVDIDNCQSHQCANGATCI 1118 Query: 383 NTADSYKCACPVTYTGKNCEVKQL 454 + + Y C C +TGK C +L Sbjct: 1119 SHTNGYSCLCFGNFTGKFCRQSRL 1142 Score = 52.8 bits (121), Expect = 7e-07 Identities = 23/74 (31%), Positives = 31/74 (41%), Gaps = 1/74 (1%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLCGPGKCMNTADSYK- 403 C N C + C E ++C C PG+ G C+ SC C G + Y Sbjct: 74 CFSNPCQGSATCVNTPGERSFLCKCPPGYSGTICETTIGSCGKNSCQHGGICHQDPIYPV 133 Query: 404 CACPVTYTGKNCEV 445 C CP Y G+ CE+ Sbjct: 134 CICPAGYAGRFCEI 147 Score = 51.6 bits (118), Expect = 2e-06 Identities = 22/76 (28%), Positives = 36/76 (47%), Gaps = 1/76 (1%) Frame = +2 Query: 224 TCAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLCGPGK-CMNTADSY 400 +C N C + G+C + VC+C G+ G C+ + C C G C + D Y Sbjct: 113 SCGKNSCQHGGICHQDPIYP--VCICPAGYAGRFCEIDHDECASSPCQNGAVCQDGIDGY 170 Query: 401 KCACPVTYTGKNCEVK 448 C C Y G++C+++ Sbjct: 171 SCFCVPGYQGRHCDLE 186 Score = 47.2 bits (107), Expect = 4e-05 Identities = 19/45 (42%), Positives = 23/45 (51%), Gaps = 1/45 (2%) Frame = +2 Query: 284 GYVCLCAPGFGGNNCDRIGESCRPGLC-GPGKCMNTADSYKCACP 415 GYVC+C PGF G +C+ C C G C N +Y C CP Sbjct: 268 GYVCICQPGFTGIHCEEDVNECSSNPCQNGGTCENLPGNYTCHCP 312 Score = 46.8 bits (106), Expect = 5e-05 Identities = 24/80 (30%), Positives = 35/80 (43%), Gaps = 3/80 (3%) Frame = +2 Query: 212 QNCFTCAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLC-GPGKCMNT 388 +N C N C NN C++ ++ C +CD + + C C G C+NT Sbjct: 29 KNNTRCLSNSCQNNSTCKDFSKDNDCSCSDTANNLDKDCDNMKDPCFSNPCQGSATCVNT 88 Query: 389 AD--SYKCACPVTYTGKNCE 442 S+ C CP Y+G CE Sbjct: 89 PGERSFLCKCPPGYSGTICE 108 Score = 42.7 bits (96), Expect = 8e-04 Identities = 38/151 (25%), Positives = 61/151 (40%), Gaps = 12/151 (7%) Frame = +2 Query: 29 SPDQWTVLELNQPLYIGGVPDFDQLPIDLAGASGFVGCISMLILGNEE-------KNIMA 187 S W + E +YIGG+PD + ++ F GCI + L N+ N + Sbjct: 706 SASTWKI-EKGDVIYIGGLPDKQETELN---GGFFKGCIQDVRLNNQNLEFFPNPTNNAS 761 Query: 188 LALEKENV-QNCF---TCAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRP 355 L NV Q C +C N C N GVC + + C C G C+ + + C Sbjct: 762 LNPVLVNVTQGCAGDNSCKSNPCHNGGVCHSRWDD--FSCSCPALTSGKACEEV-QWCGF 818 Query: 356 GLCGPG-KCMNTADSYKCACPVTYTGKNCEV 445 C G +C ++C + G++ ++ Sbjct: 819 SPCPHGAQCQPVLQGFECIANAVFNGQSGQI 849 Score = 40.7 bits (91), Expect = 0.003 Identities = 24/88 (27%), Positives = 35/88 (39%), Gaps = 9/88 (10%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVC----LCAPGFGGNNCDRIGESCRPGLC-GPGKCM--- 382 C+ N C N G C+ + C L +GG +C I C C G C+ Sbjct: 289 CSSNPCQNGGTCENLPGNYTCHCPFDNLSRTFYGGRDCSDILLGCTHQQCLNNGTCIPHF 348 Query: 383 -NTADSYKCACPVTYTGKNCEVKQLIEY 463 + + C CP YTG CE+ + + Sbjct: 349 QDGQHGFSCLCPSGYTGSLCEIATTLSF 376 Score = 37.1 bits (82), Expect = 0.039 Identities = 14/35 (40%), Positives = 21/35 (60%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCD 331 CA + C+N G+CQ+ L + + CLC F G C+ Sbjct: 1189 CASDPCVNGGLCQDLLNK--FQCLCDVAFAGERCE 1221 Score = 33.1 bits (72), Expect = 0.63 Identities = 14/37 (37%), Positives = 19/37 (51%), Gaps = 1/37 (2%) Frame = +2 Query: 344 SCRPGLC-GPGKCMNTADSYKCACPVTYTGKNCEVKQ 451 SC+ C G C + D + C+CP +GK CE Q Sbjct: 778 SCKSNPCHNGGVCHSRWDDFSCSCPALTSGKACEEVQ 814 Score = 29.9 bits (64), Expect = 5.9 Identities = 11/23 (47%), Positives = 14/23 (60%) Frame = +2 Query: 371 GKCMNTADSYKCACPVTYTGKNC 439 G+C+N SY+C C Y G NC Sbjct: 573 GRCINLWLSYQCDCHRPYEGPNC 595 >AL136322-4|CAM23328.1| 1294|Homo sapiens crumbs homolog 1 (Drosophila) protein. Length = 1294 Score = 63.7 bits (148), Expect = 4e-10 Identities = 29/77 (37%), Positives = 37/77 (48%), Gaps = 4/77 (5%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLC-GPGKCMNTADSYK 403 CA + C N VCQ+ + GY C C PG+ G +CD + C C C+N Y Sbjct: 152 CASSPCQNGAVCQDGID--GYSCFCVPGYQGRHCDLEVDECASDPCKNEATCLNEIGRYT 209 Query: 404 CACPVT---YTGKNCEV 445 C CP YTG CE+ Sbjct: 210 CICPHNYSGYTGAQCEI 226 Score = 58.8 bits (136), Expect = 1e-08 Identities = 26/73 (35%), Positives = 36/73 (49%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLCGPGKCMNTADSYKC 406 C N CL+ G C++ + Y C C G+ G +C+ + C C G C + +Y C Sbjct: 1031 CNSNPCLHGGNCEDIYSS--YHCSCPLGWSGKHCELNIDECFSNPCIHGNCSDRVAAYHC 1088 Query: 407 ACPVTYTGKNCEV 445 C YTG NCEV Sbjct: 1089 TCEPGYTGVNCEV 1101 Score = 56.4 bits (130), Expect = 6e-08 Identities = 25/69 (36%), Positives = 35/69 (50%), Gaps = 1/69 (1%) Frame = +2 Query: 242 CLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLC-GPGKCMNTADSYKCACPV 418 C N G C E TE C+C PGF G C++ + C C G C + + ++C C V Sbjct: 1156 CYNGGNCTEFQTE--LKCMCRPGFTGEWCEKDIDECASDPCVNGGLCQDLLNKFQCLCDV 1213 Query: 419 TYTGKNCEV 445 + G+ CEV Sbjct: 1214 AFAGERCEV 1222 Score = 53.6 bits (123), Expect = 4e-07 Identities = 27/84 (32%), Positives = 43/84 (51%), Gaps = 1/84 (1%) Frame = +2 Query: 206 NVQNCFTCAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLCGPG-KCM 382 N+ CF+ N C++ G C + + Y C C PG+ G NC+ ++C+ C G C+ Sbjct: 1065 NIDECFS---NPCIH-GNCSDRVA--AYHCTCEPGYTGVNCEVDIDNCQSHQCANGATCI 1118 Query: 383 NTADSYKCACPVTYTGKNCEVKQL 454 + + Y C C +TGK C +L Sbjct: 1119 SHTNGYSCLCFGNFTGKFCRQSRL 1142 Score = 52.8 bits (121), Expect = 7e-07 Identities = 23/74 (31%), Positives = 31/74 (41%), Gaps = 1/74 (1%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLCGPGKCMNTADSYK- 403 C N C + C E ++C C PG+ G C+ SC C G + Y Sbjct: 74 CFSNPCQGSATCVNTPGERSFLCKCPPGYSGTICETTIGSCGKNSCQHGGICHQDPIYPV 133 Query: 404 CACPVTYTGKNCEV 445 C CP Y G+ CE+ Sbjct: 134 CICPAGYAGRFCEI 147 Score = 51.6 bits (118), Expect = 2e-06 Identities = 22/76 (28%), Positives = 36/76 (47%), Gaps = 1/76 (1%) Frame = +2 Query: 224 TCAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLCGPGK-CMNTADSY 400 +C N C + G+C + VC+C G+ G C+ + C C G C + D Y Sbjct: 113 SCGKNSCQHGGICHQDPIYP--VCICPAGYAGRFCEIDHDECASSPCQNGAVCQDGIDGY 170 Query: 401 KCACPVTYTGKNCEVK 448 C C Y G++C+++ Sbjct: 171 SCFCVPGYQGRHCDLE 186 Score = 47.2 bits (107), Expect = 4e-05 Identities = 19/45 (42%), Positives = 23/45 (51%), Gaps = 1/45 (2%) Frame = +2 Query: 284 GYVCLCAPGFGGNNCDRIGESCRPGLC-GPGKCMNTADSYKCACP 415 GYVC+C PGF G +C+ C C G C N +Y C CP Sbjct: 268 GYVCICQPGFTGIHCEEDVNECSSNPCQNGGTCENLPGNYTCHCP 312 Score = 46.8 bits (106), Expect = 5e-05 Identities = 24/80 (30%), Positives = 35/80 (43%), Gaps = 3/80 (3%) Frame = +2 Query: 212 QNCFTCAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLC-GPGKCMNT 388 +N C N C NN C++ ++ C +CD + + C C G C+NT Sbjct: 29 KNNTRCLSNSCQNNSTCKDFSKDNDCSCSDTANNLDKDCDNMKDPCFSNPCQGSATCVNT 88 Query: 389 AD--SYKCACPVTYTGKNCE 442 S+ C CP Y+G CE Sbjct: 89 PGERSFLCKCPPGYSGTICE 108 Score = 42.7 bits (96), Expect = 8e-04 Identities = 38/151 (25%), Positives = 61/151 (40%), Gaps = 12/151 (7%) Frame = +2 Query: 29 SPDQWTVLELNQPLYIGGVPDFDQLPIDLAGASGFVGCISMLILGNEE-------KNIMA 187 S W + E +YIGG+PD + ++ F GCI + L N+ N + Sbjct: 706 SASTWKI-EKGDVIYIGGLPDKQETELN---GGFFKGCIQDVRLNNQNLEFFPNPTNNAS 761 Query: 188 LALEKENV-QNCF---TCAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRP 355 L NV Q C +C N C N GVC + + C C G C+ + + C Sbjct: 762 LNPVLVNVTQGCAGDNSCKSNPCHNGGVCHSRWDD--FSCSCPALTSGKACEEV-QWCGF 818 Query: 356 GLCGPG-KCMNTADSYKCACPVTYTGKNCEV 445 C G +C ++C + G++ ++ Sbjct: 819 SPCPHGAQCQPVLQGFECIANAVFNGQSGQI 849 Score = 40.7 bits (91), Expect = 0.003 Identities = 24/88 (27%), Positives = 35/88 (39%), Gaps = 9/88 (10%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVC----LCAPGFGGNNCDRIGESCRPGLC-GPGKCM--- 382 C+ N C N G C+ + C L +GG +C I C C G C+ Sbjct: 289 CSSNPCQNGGTCENLPGNYTCHCPFDNLSRTFYGGRDCSDILLGCTHQQCLNNGTCIPHF 348 Query: 383 -NTADSYKCACPVTYTGKNCEVKQLIEY 463 + + C CP YTG CE+ + + Sbjct: 349 QDGQHGFSCLCPSGYTGSLCEIATTLSF 376 Score = 37.1 bits (82), Expect = 0.039 Identities = 14/35 (40%), Positives = 21/35 (60%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCD 331 CA + C+N G+CQ+ L + + CLC F G C+ Sbjct: 1189 CASDPCVNGGLCQDLLNK--FQCLCDVAFAGERCE 1221 Score = 33.1 bits (72), Expect = 0.63 Identities = 14/37 (37%), Positives = 19/37 (51%), Gaps = 1/37 (2%) Frame = +2 Query: 344 SCRPGLC-GPGKCMNTADSYKCACPVTYTGKNCEVKQ 451 SC+ C G C + D + C+CP +GK CE Q Sbjct: 778 SCKSNPCHNGGVCHSRWDDFSCSCPALTSGKACEEVQ 814 Score = 29.9 bits (64), Expect = 5.9 Identities = 11/23 (47%), Positives = 14/23 (60%) Frame = +2 Query: 371 GKCMNTADSYKCACPVTYTGKNC 439 G+C+N SY+C C Y G NC Sbjct: 573 GRCINLWLSYQCDCHRPYEGPNC 595 >AJ748821-1|CAG38658.1| 1294|Homo sapiens crumbs homologue 1 (alternative protein) protein. Length = 1294 Score = 63.7 bits (148), Expect = 4e-10 Identities = 29/77 (37%), Positives = 37/77 (48%), Gaps = 4/77 (5%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLC-GPGKCMNTADSYK 403 CA + C N VCQ+ + GY C C PG+ G +CD + C C C+N Y Sbjct: 152 CASSPCQNGAVCQDGID--GYSCFCVPGYQGRHCDLEVDECASDPCKNEATCLNEIGRYT 209 Query: 404 CACPVT---YTGKNCEV 445 C CP YTG CE+ Sbjct: 210 CICPHNYSGYTGAQCEI 226 Score = 58.8 bits (136), Expect = 1e-08 Identities = 26/73 (35%), Positives = 36/73 (49%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLCGPGKCMNTADSYKC 406 C N CL+ G C++ + Y C C G+ G +C+ + C C G C + +Y C Sbjct: 1031 CNSNPCLHGGNCEDIYSS--YHCSCPLGWSGKHCELNIDECFSNPCIHGNCSDRVAAYHC 1088 Query: 407 ACPVTYTGKNCEV 445 C YTG NCEV Sbjct: 1089 TCEPGYTGVNCEV 1101 Score = 56.4 bits (130), Expect = 6e-08 Identities = 25/69 (36%), Positives = 35/69 (50%), Gaps = 1/69 (1%) Frame = +2 Query: 242 CLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLC-GPGKCMNTADSYKCACPV 418 C N G C E TE C+C PGF G C++ + C C G C + + ++C C V Sbjct: 1156 CYNGGNCTEFQTE--LKCMCRPGFTGEWCEKDIDECASDPCVNGGLCQDLLNKFQCLCDV 1213 Query: 419 TYTGKNCEV 445 + G+ CEV Sbjct: 1214 AFAGERCEV 1222 Score = 53.6 bits (123), Expect = 4e-07 Identities = 27/84 (32%), Positives = 43/84 (51%), Gaps = 1/84 (1%) Frame = +2 Query: 206 NVQNCFTCAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLCGPG-KCM 382 N+ CF+ N C++ G C + + Y C C PG+ G NC+ ++C+ C G C+ Sbjct: 1065 NIDECFS---NPCIH-GNCSDRVA--AYHCTCEPGYTGVNCEVDIDNCQSHQCANGATCI 1118 Query: 383 NTADSYKCACPVTYTGKNCEVKQL 454 + + Y C C +TGK C +L Sbjct: 1119 SHTNGYSCLCFGNFTGKFCRQSRL 1142 Score = 52.8 bits (121), Expect = 7e-07 Identities = 23/74 (31%), Positives = 31/74 (41%), Gaps = 1/74 (1%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLCGPGKCMNTADSYK- 403 C N C + C E ++C C PG+ G C+ SC C G + Y Sbjct: 74 CFSNPCQGSATCVNTPGERSFLCKCPPGYSGTICETTIGSCGKNSCQHGGICHQDPIYPV 133 Query: 404 CACPVTYTGKNCEV 445 C CP Y G+ CE+ Sbjct: 134 CICPAGYAGRFCEI 147 Score = 51.6 bits (118), Expect = 2e-06 Identities = 22/76 (28%), Positives = 36/76 (47%), Gaps = 1/76 (1%) Frame = +2 Query: 224 TCAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLCGPGK-CMNTADSY 400 +C N C + G+C + VC+C G+ G C+ + C C G C + D Y Sbjct: 113 SCGKNSCQHGGICHQDPIYP--VCICPAGYAGRFCEIDHDECASSPCQNGAVCQDGIDGY 170 Query: 401 KCACPVTYTGKNCEVK 448 C C Y G++C+++ Sbjct: 171 SCFCVPGYQGRHCDLE 186 Score = 47.2 bits (107), Expect = 4e-05 Identities = 19/45 (42%), Positives = 23/45 (51%), Gaps = 1/45 (2%) Frame = +2 Query: 284 GYVCLCAPGFGGNNCDRIGESCRPGLC-GPGKCMNTADSYKCACP 415 GYVC+C PGF G +C+ C C G C N +Y C CP Sbjct: 268 GYVCICQPGFTGIHCEEDVNECSSNPCQNGGTCENLPGNYTCHCP 312 Score = 46.8 bits (106), Expect = 5e-05 Identities = 24/80 (30%), Positives = 35/80 (43%), Gaps = 3/80 (3%) Frame = +2 Query: 212 QNCFTCAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLC-GPGKCMNT 388 +N C N C NN C++ ++ C +CD + + C C G C+NT Sbjct: 29 KNNTRCLSNSCQNNSTCKDFSKDNDCSCSDTANNLDKDCDNMKDPCFSNPCQGSATCVNT 88 Query: 389 AD--SYKCACPVTYTGKNCE 442 S+ C CP Y+G CE Sbjct: 89 PGERSFLCKCPPGYSGTICE 108 Score = 42.7 bits (96), Expect = 8e-04 Identities = 38/151 (25%), Positives = 61/151 (40%), Gaps = 12/151 (7%) Frame = +2 Query: 29 SPDQWTVLELNQPLYIGGVPDFDQLPIDLAGASGFVGCISMLILGNEE-------KNIMA 187 S W + E +YIGG+PD + ++ F GCI + L N+ N + Sbjct: 706 SASTWKI-EKGDVIYIGGLPDKQETELN---GGFFKGCIQDVRLNNQNLEFFPNPTNNAS 761 Query: 188 LALEKENV-QNCF---TCAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRP 355 L NV Q C +C N C N GVC + + C C G C+ + + C Sbjct: 762 LNPVLVNVTQGCAGDNSCKSNPCHNGGVCHSRWDD--FSCSCPALTSGKACEEV-QWCGF 818 Query: 356 GLCGPG-KCMNTADSYKCACPVTYTGKNCEV 445 C G +C ++C + G++ ++ Sbjct: 819 SPCPHGAQCQPVLQGFECIANAVFNGQSGQI 849 Score = 40.7 bits (91), Expect = 0.003 Identities = 24/88 (27%), Positives = 35/88 (39%), Gaps = 9/88 (10%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVC----LCAPGFGGNNCDRIGESCRPGLC-GPGKCM--- 382 C+ N C N G C+ + C L +GG +C I C C G C+ Sbjct: 289 CSSNPCQNGGTCENLPGNYTCHCPFDNLSRTFYGGRDCSDILLGCTHQQCLNNGTCIPHF 348 Query: 383 -NTADSYKCACPVTYTGKNCEVKQLIEY 463 + + C CP YTG CE+ + + Sbjct: 349 QDGQHGFSCLCPSGYTGSLCEIATTLSF 376 Score = 37.1 bits (82), Expect = 0.039 Identities = 14/35 (40%), Positives = 21/35 (60%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCD 331 CA + C+N G+CQ+ L + + CLC F G C+ Sbjct: 1189 CASDPCVNGGLCQDLLNK--FQCLCDVAFAGERCE 1221 Score = 33.1 bits (72), Expect = 0.63 Identities = 14/37 (37%), Positives = 19/37 (51%), Gaps = 1/37 (2%) Frame = +2 Query: 344 SCRPGLC-GPGKCMNTADSYKCACPVTYTGKNCEVKQ 451 SC+ C G C + D + C+CP +GK CE Q Sbjct: 778 SCKSNPCHNGGVCHSRWDDFSCSCPALTSGKACEEVQ 814 Score = 29.9 bits (64), Expect = 5.9 Identities = 11/23 (47%), Positives = 14/23 (60%) Frame = +2 Query: 371 GKCMNTADSYKCACPVTYTGKNC 439 G+C+N SY+C C Y G NC Sbjct: 573 GRCINLWLSYQCDCHRPYEGPNC 595 >U77914-1|AAC50909.1| 263|Homo sapiens soluble protein Jagged protein. Length = 263 Score = 63.3 bits (147), Expect = 5e-10 Identities = 27/78 (34%), Positives = 42/78 (53%), Gaps = 1/78 (1%) Frame = +2 Query: 212 QNCFTCAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLCGPG-KCMNT 388 QN C+P+ C N+G C + ++ Y C CAPGF G +C C+ C G C++ Sbjct: 39 QNTNDCSPHPCYNSGTCVDG--DNWYRCECAPGFAGPDCRININECQSSPCAFGATCVDE 96 Query: 389 ADSYKCACPVTYTGKNCE 442 + Y+C CP ++G C+ Sbjct: 97 INGYRCVCPPGHSGAKCQ 114 Score = 52.4 bits (120), Expect = 1e-06 Identities = 22/75 (29%), Positives = 35/75 (46%), Gaps = 1/75 (1%) Frame = +2 Query: 224 TCAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLC-GPGKCMNTADSY 400 +C PN C N G C + + C+C G+ G C + C P C G C++ + Y Sbjct: 5 SCLPNPCHNGGTC--VVNGESFTCVCKEGWEGPICAQNTNDCSPHPCYNSGTCVDGDNWY 62 Query: 401 KCACPVTYTGKNCEV 445 +C C + G +C + Sbjct: 63 RCECAPGFAGPDCRI 77 Score = 31.5 bits (68), Expect = 1.9 Identities = 14/46 (30%), Positives = 20/46 (43%), Gaps = 1/46 (2%) Frame = +2 Query: 215 NCFTCAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRI-GESC 349 N C + C C + + +GY C+C PG G C + G C Sbjct: 78 NINECQSSPCAFGATCVDEI--NGYRCVCPPGHSGAKCQEVSGRPC 121 >X15998-1|CAA34128.1| 2409|Homo sapiens protein ( H.sapiens mRNA for the chondroitin sulphate proteoglycan versican, V1 splice-variant; precursor peptide. ). Length = 2409 Score = 62.9 bits (146), Expect = 7e-10 Identities = 27/73 (36%), Positives = 38/73 (52%), Gaps = 1/73 (1%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLCGPG-KCMNTADSYK 403 C N CLN G C TE YVC C PG+ G+ C+ + C C G C++ ++++ Sbjct: 2106 CKMNPCLNGGTCYP--TETSYVCTCVPGYSGDQCELDFDECHSNPCRNGATCVDGFNTFR 2163 Query: 404 CACPVTYTGKNCE 442 C C +Y G CE Sbjct: 2164 CLCLPSYVGALCE 2176 Score = 31.9 bits (69), Expect = 1.5 Identities = 14/44 (31%), Positives = 20/44 (45%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPG 358 C N C N C + + CLC P + G C++ E+C G Sbjct: 2144 CHSNPCRNGATCVDGFNT--FRCLCLPSYVGALCEQDTETCDYG 2185 Score = 30.7 bits (66), Expect = 3.4 Identities = 13/36 (36%), Positives = 17/36 (47%), Gaps = 1/36 (2%) Frame = +2 Query: 341 ESCRPGLC-GPGKCMNTADSYKCACPVTYTGKNCEV 445 + C+ C G C T SY C C Y+G CE+ Sbjct: 2104 DRCKMNPCLNGGTCYPTETSYVCTCVPGYSGDQCEL 2139 >U77493-1|AAB19224.1| 263|Homo sapiens Notch2 protein. Length = 263 Score = 62.9 bits (146), Expect = 7e-10 Identities = 27/77 (35%), Positives = 40/77 (51%), Gaps = 1/77 (1%) Frame = +2 Query: 215 NCFTCAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLC-GPGKCMNTA 391 N C + C N G C + + + + CLC GF G+ C C C G C++ Sbjct: 21 NINECTESSCFNGGTCVDGI--NSFSCLCPVGFTGSFCLHEINECSSHPCLNDGTCVDGL 78 Query: 392 DSYKCACPVTYTGKNCE 442 +Y+C+CP+ YTGKNC+ Sbjct: 79 GTYRCSCPLGYTGKNCQ 95 Score = 55.6 bits (128), Expect = 1e-07 Identities = 25/73 (34%), Positives = 37/73 (50%), Gaps = 1/73 (1%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLC-GPGKCMNTADSYK 403 CA N C + C + + GY C C PG+ G NC+ + C+ C G C++ + +K Sbjct: 187 CASNPCQHGATCSDFIG--GYRCECVPGYQGVNCEYEVDECQNQPCQNGGTCIDLVNHFK 244 Query: 404 CACPVTYTGKNCE 442 C+CP G CE Sbjct: 245 CSCPPGTRGLLCE 257 Score = 53.6 bits (123), Expect = 4e-07 Identities = 25/74 (33%), Positives = 35/74 (47%), Gaps = 1/74 (1%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLC-GPGKCMNTADSYK 403 C+ + CLN+G C + L Y C C G+ G NC + C C G C+ S + Sbjct: 63 CSSHPCLNDGTCVDGLGT--YRCSCPLGYTGKNCQTLVNLCSRSPCKNKGTCVQKKASPQ 120 Query: 404 CACPVTYTGKNCEV 445 C CP + G C+V Sbjct: 121 CLCPSGWVGAYCDV 134 Score = 49.2 bits (112), Expect = 9e-06 Identities = 21/65 (32%), Positives = 32/65 (49%), Gaps = 3/65 (4%) Frame = +2 Query: 281 HGYVCLCAPGFGGNNCDRIGESCRPGLC-GPGKCMNTADSYKCACPVTYTGKNC--EVKQ 451 + Y C C GF G +C+ C C G C++ +S+ C CPV +TG C E+ + Sbjct: 3 NSYTCKCQAGFDGVHCENNINECTESSCFNGGTCVDGINSFSCLCPVGFTGSFCLHEINE 62 Query: 452 LIEYP 466 +P Sbjct: 63 CSSHP 67 Score = 48.4 bits (110), Expect = 2e-05 Identities = 36/98 (36%), Positives = 46/98 (46%), Gaps = 15/98 (15%) Frame = +2 Query: 212 QNCFT----CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESC-----RPG-- 358 +NC T C+ + C N G C + CLC G+ G CD SC R G Sbjct: 92 KNCQTLVNLCSRSPCKNKGTCVQKKASPQ--CLCPSGWVGAYCDVPNVSCDIAASRRGVL 149 Query: 359 ---LCG-PGKCMNTADSYKCACPVTYTGKNCEVKQLIE 460 LC G C+N +++ C CPV YTG CE +QL E Sbjct: 150 VEHLCQHSGVCINAGNTHYCQCPVGYTGSYCE-EQLDE 186 >U16306-1|AAA65018.1| 3396|Homo sapiens chondroitin sulfate proteoglycan versican V0 splice-variant precursor peptide protein. Length = 3396 Score = 62.9 bits (146), Expect = 7e-10 Identities = 27/73 (36%), Positives = 38/73 (52%), Gaps = 1/73 (1%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLCGPG-KCMNTADSYK 403 C N CLN G C TE YVC C PG+ G+ C+ + C C G C++ ++++ Sbjct: 3093 CKMNPCLNGGTCYP--TETSYVCTCVPGYSGDQCELDFDECHSNPCRNGATCVDGFNTFR 3150 Query: 404 CACPVTYTGKNCE 442 C C +Y G CE Sbjct: 3151 CLCLPSYVGALCE 3163 Score = 31.9 bits (69), Expect = 1.5 Identities = 14/44 (31%), Positives = 20/44 (45%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPG 358 C N C N C + + CLC P + G C++ E+C G Sbjct: 3131 CHSNPCRNGATCVDGFNT--FRCLCLPSYVGALCEQDTETCDYG 3172 Score = 30.7 bits (66), Expect = 3.4 Identities = 13/36 (36%), Positives = 17/36 (47%), Gaps = 1/36 (2%) Frame = +2 Query: 341 ESCRPGLC-GPGKCMNTADSYKCACPVTYTGKNCEV 445 + C+ C G C T SY C C Y+G CE+ Sbjct: 3091 DRCKMNPCLNGGTCYPTETSYVCTCVPGYSGDQCEL 3126 >J02814-1|AAA36437.1| 688|Homo sapiens protein ( Human chondroitin sulfate proteoglycan core protein mRNA, 3' end. ). Length = 688 Score = 62.9 bits (146), Expect = 7e-10 Identities = 27/73 (36%), Positives = 38/73 (52%), Gaps = 1/73 (1%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLCGPG-KCMNTADSYK 403 C N CLN G C TE YVC C PG+ G+ C+ + C C G C++ ++++ Sbjct: 385 CKMNPCLNGGTCYP--TETSYVCTCVPGYSGDQCELDFDECHSNPCRNGATCVDGFNTFR 442 Query: 404 CACPVTYTGKNCE 442 C C +Y G CE Sbjct: 443 CLCLPSYVGALCE 455 Score = 31.9 bits (69), Expect = 1.5 Identities = 14/44 (31%), Positives = 20/44 (45%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPG 358 C N C N C + + CLC P + G C++ E+C G Sbjct: 423 CHSNPCRNGATCVDGFNT--FRCLCLPSYVGALCEQDTETCDYG 464 Score = 30.7 bits (66), Expect = 3.4 Identities = 13/36 (36%), Positives = 17/36 (47%), Gaps = 1/36 (2%) Frame = +2 Query: 341 ESCRPGLC-GPGKCMNTADSYKCACPVTYTGKNCEV 445 + C+ C G C T SY C C Y+G CE+ Sbjct: 383 DRCKMNPCLNGGTCYPTETSYVCTCVPGYSGDQCEL 418 >D32039-1|BAA06801.1| 655|Homo sapiens proteoglycan PG-M(V3) protein. Length = 655 Score = 62.9 bits (146), Expect = 7e-10 Identities = 27/73 (36%), Positives = 38/73 (52%), Gaps = 1/73 (1%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLCGPG-KCMNTADSYK 403 C N CLN G C TE YVC C PG+ G+ C+ + C C G C++ ++++ Sbjct: 352 CKMNPCLNGGTCYP--TETSYVCTCVPGYSGDQCELDFDECHSNPCRNGATCVDGFNTFR 409 Query: 404 CACPVTYTGKNCE 442 C C +Y G CE Sbjct: 410 CLCLPSYVGALCE 422 Score = 31.9 bits (69), Expect = 1.5 Identities = 14/41 (34%), Positives = 19/41 (46%), Gaps = 1/41 (2%) Frame = +2 Query: 326 CDRIGESCRPGLC-GPGKCMNTADSYKCACPVTYTGKNCEV 445 C + + C+ C G C T SY C C Y+G CE+ Sbjct: 345 CFKRPDRCKMNPCLNGGTCYPTETSYVCTCVPGYSGDQCEL 385 Score = 31.9 bits (69), Expect = 1.5 Identities = 14/44 (31%), Positives = 20/44 (45%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPG 358 C N C N C + + CLC P + G C++ E+C G Sbjct: 390 CHSNPCRNGATCVDGFNT--FRCLCLPSYVGALCEQDTETCDYG 431 >BX641036-1|CAE46022.1| 2060|Homo sapiens hypothetical protein protein. Length = 2060 Score = 62.9 bits (146), Expect = 7e-10 Identities = 27/73 (36%), Positives = 38/73 (52%), Gaps = 1/73 (1%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLCGPG-KCMNTADSYK 403 C N CLN G C TE YVC C PG+ G+ C+ + C C G C++ ++++ Sbjct: 1757 CKMNPCLNGGTCYP--TETSYVCTCVPGYSGDQCELDFDECHSNPCRNGATCVDGFNTFR 1814 Query: 404 CACPVTYTGKNCE 442 C C +Y G CE Sbjct: 1815 CLCLPSYVGALCE 1827 Score = 31.9 bits (69), Expect = 1.5 Identities = 14/44 (31%), Positives = 20/44 (45%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPG 358 C N C N C + + CLC P + G C++ E+C G Sbjct: 1795 CHSNPCRNGATCVDGFNT--FRCLCLPSYVGALCEQDTETCDYG 1836 Score = 30.7 bits (66), Expect = 3.4 Identities = 13/36 (36%), Positives = 17/36 (47%), Gaps = 1/36 (2%) Frame = +2 Query: 341 ESCRPGLC-GPGKCMNTADSYKCACPVTYTGKNCEV 445 + C+ C G C T SY C C Y+G CE+ Sbjct: 1755 DRCKMNPCLNGGTCYPTETSYVCTCVPGYSGDQCEL 1790 >AB209491-1|BAD92728.1| 3410|Homo sapiens chondroitin sulfate proteoglycan 2 (versican) variant protein. Length = 3410 Score = 62.9 bits (146), Expect = 7e-10 Identities = 27/73 (36%), Positives = 38/73 (52%), Gaps = 1/73 (1%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLCGPG-KCMNTADSYK 403 C N CLN G C TE YVC C PG+ G+ C+ + C C G C++ ++++ Sbjct: 3107 CKMNPCLNGGTCYP--TETSYVCTCVPGYSGDQCELDFDECHSNPCRNGATCVDGFNTFR 3164 Query: 404 CACPVTYTGKNCE 442 C C +Y G CE Sbjct: 3165 CLCLPSYVGALCE 3177 Score = 31.9 bits (69), Expect = 1.5 Identities = 14/44 (31%), Positives = 20/44 (45%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPG 358 C N C N C + + CLC P + G C++ E+C G Sbjct: 3145 CHSNPCRNGATCVDGFNT--FRCLCLPSYVGALCEQDTETCDYG 3186 Score = 30.7 bits (66), Expect = 3.4 Identities = 13/36 (36%), Positives = 17/36 (47%), Gaps = 1/36 (2%) Frame = +2 Query: 341 ESCRPGLC-GPGKCMNTADSYKCACPVTYTGKNCEV 445 + C+ C G C T SY C C Y+G CE+ Sbjct: 3105 DRCKMNPCLNGGTCYPTETSYVCTCVPGYSGDQCEL 3140 >S83182-1|AAB46909.1| 560|Homo sapiens hyaluronan-binding protein protein. Length = 560 Score = 61.7 bits (143), Expect = 2e-09 Identities = 33/102 (32%), Positives = 47/102 (46%), Gaps = 10/102 (9%) Frame = +2 Query: 164 NEEKNIMALALEKENVQNCFT------CAPNLCLNNGVCQEALTEHG--YVCLCAPGFGG 319 N+E+N + EN +T C PN C + G C HG + C C F G Sbjct: 50 NQEENTSSTLTHAENPDWYYTEDQADPCQPNPCEHGGDC----LVHGSTFTCSCLAPFSG 105 Query: 320 NNCDRIGESCRPGLCGPGKCMNTADS--YKCACPVTYTGKNC 439 N C ++ +C+ CG G+C+ T Y+C C YTG +C Sbjct: 106 NKCQKVQNTCKDNPCGRGQCLITQSPPYYRCVCKHPYTGPSC 147 Score = 49.6 bits (113), Expect = 7e-06 Identities = 28/84 (33%), Positives = 38/84 (45%), Gaps = 3/84 (3%) Frame = +2 Query: 203 ENVQNCFTCAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLCGPG-KC 379 + VQN TC N C G C + Y C+C + G +C ++ CRP C G C Sbjct: 109 QKVQN--TCKDNPC-GRGQCLITQSPPYYRCVCKHPYTGPSCSQVVPVCRPNPCQNGATC 165 Query: 380 M--NTADSYKCACPVTYTGKNCEV 445 + CACP + GK CE+ Sbjct: 166 SRHKRRSKFTCACPDQFKGKFCEI 189 Score = 35.1 bits (77), Expect = 0.16 Identities = 17/62 (27%), Positives = 22/62 (35%), Gaps = 2/62 (3%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESC--RPGLCGPGKCMNTADSY 400 C PN C N C + C C F G C+ + C G GK T + + Sbjct: 154 CRPNPCQNGATCSRHKRRSKFTCACPDQFKGKFCEIGSDDCYVGDGYSYRGKMNRTVNQH 213 Query: 401 KC 406 C Sbjct: 214 AC 215 >D49742-1|BAA08576.1| 560|Homo sapiens HGF activator like protein protein. Length = 560 Score = 61.7 bits (143), Expect = 2e-09 Identities = 33/102 (32%), Positives = 47/102 (46%), Gaps = 10/102 (9%) Frame = +2 Query: 164 NEEKNIMALALEKENVQNCFT------CAPNLCLNNGVCQEALTEHG--YVCLCAPGFGG 319 N+E+N + EN +T C PN C + G C HG + C C F G Sbjct: 50 NQEENTSSTLTHAENPDWYYTEDQADPCQPNPCEHGGDC----LVHGSTFTCSCLAPFSG 105 Query: 320 NNCDRIGESCRPGLCGPGKCMNTADS--YKCACPVTYTGKNC 439 N C ++ +C+ CG G+C+ T Y+C C YTG +C Sbjct: 106 NKCQKVQNTCKDNPCGRGQCLITQSPPYYRCVCKHPYTGPSC 147 Score = 49.6 bits (113), Expect = 7e-06 Identities = 28/84 (33%), Positives = 38/84 (45%), Gaps = 3/84 (3%) Frame = +2 Query: 203 ENVQNCFTCAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLCGPG-KC 379 + VQN TC N C G C + Y C+C + G +C ++ CRP C G C Sbjct: 109 QKVQN--TCKDNPC-GRGQCLITQSPPYYRCVCKHPYTGPSCSQVVPVCRPNPCQNGATC 165 Query: 380 M--NTADSYKCACPVTYTGKNCEV 445 + CACP + GK CE+ Sbjct: 166 SRHKRRSKFTCACPDQFKGKFCEI 189 Score = 35.1 bits (77), Expect = 0.16 Identities = 17/62 (27%), Positives = 22/62 (35%), Gaps = 2/62 (3%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESC--RPGLCGPGKCMNTADSY 400 C PN C N C + C C F G C+ + C G GK T + + Sbjct: 154 CRPNPCQNGATCSRHKRRSKFTCACPDQFKGKFCEIGSDDCYVGDGYSYRGKMNRTVNQH 213 Query: 401 KC 406 C Sbjct: 214 AC 215 >BC031412-1|AAH31412.1| 560|Homo sapiens hyaluronan binding protein 2 protein. Length = 560 Score = 61.7 bits (143), Expect = 2e-09 Identities = 33/102 (32%), Positives = 47/102 (46%), Gaps = 10/102 (9%) Frame = +2 Query: 164 NEEKNIMALALEKENVQNCFT------CAPNLCLNNGVCQEALTEHG--YVCLCAPGFGG 319 N+E+N + EN +T C PN C + G C HG + C C F G Sbjct: 50 NQEENTSSTLTHAENPDWYYTEDQADPCQPNPCEHGGDC----LVHGSTFTCSCLAPFSG 105 Query: 320 NNCDRIGESCRPGLCGPGKCMNTADS--YKCACPVTYTGKNC 439 N C ++ +C+ CG G+C+ T Y+C C YTG +C Sbjct: 106 NKCQKVQNTCKDNPCGRGQCLITQSPPYYRCVCKHPYTGPSC 147 Score = 49.6 bits (113), Expect = 7e-06 Identities = 28/84 (33%), Positives = 38/84 (45%), Gaps = 3/84 (3%) Frame = +2 Query: 203 ENVQNCFTCAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLCGPG-KC 379 + VQN TC N C G C + Y C+C + G +C ++ CRP C G C Sbjct: 109 QKVQN--TCKDNPC-GRGQCLITQSPPYYRCVCKHPYTGPSCSQVVPVCRPNPCQNGATC 165 Query: 380 M--NTADSYKCACPVTYTGKNCEV 445 + CACP + GK CE+ Sbjct: 166 SRHKRRSKFTCACPDQFKGKFCEI 189 Score = 35.1 bits (77), Expect = 0.16 Identities = 17/62 (27%), Positives = 22/62 (35%), Gaps = 2/62 (3%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESC--RPGLCGPGKCMNTADSY 400 C PN C N C + C C F G C+ + C G GK T + + Sbjct: 154 CRPNPCQNGATCSRHKRRSKFTCACPDQFKGKFCEIGSDDCYVGDGYSYRGKMNRTVNQH 213 Query: 401 KC 406 C Sbjct: 214 AC 215 >AY534754-1|AAS16352.1| 560|Homo sapiens hyaluronan binding protein 2 protein. Length = 560 Score = 61.7 bits (143), Expect = 2e-09 Identities = 33/102 (32%), Positives = 47/102 (46%), Gaps = 10/102 (9%) Frame = +2 Query: 164 NEEKNIMALALEKENVQNCFT------CAPNLCLNNGVCQEALTEHG--YVCLCAPGFGG 319 N+E+N + EN +T C PN C + G C HG + C C F G Sbjct: 50 NQEENTSSTLTHAENPDWYYTEDQADPCQPNPCEHGGDC----LVHGSTFTCSCLAPFSG 105 Query: 320 NNCDRIGESCRPGLCGPGKCMNTADS--YKCACPVTYTGKNC 439 N C ++ +C+ CG G+C+ T Y+C C YTG +C Sbjct: 106 NKCQKVQNTCKDNPCGRGQCLITQSPPYYRCVCKHPYTGPSC 147 Score = 49.6 bits (113), Expect = 7e-06 Identities = 28/84 (33%), Positives = 38/84 (45%), Gaps = 3/84 (3%) Frame = +2 Query: 203 ENVQNCFTCAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLCGPG-KC 379 + VQN TC N C G C + Y C+C + G +C ++ CRP C G C Sbjct: 109 QKVQN--TCKDNPC-GRGQCLITQSPPYYRCVCKHPYTGPSCSQVVPVCRPNPCQNGATC 165 Query: 380 M--NTADSYKCACPVTYTGKNCEV 445 + CACP + GK CE+ Sbjct: 166 SRHKRRSKFTCACPDQFKGKFCEI 189 Score = 35.1 bits (77), Expect = 0.16 Identities = 17/62 (27%), Positives = 22/62 (35%), Gaps = 2/62 (3%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESC--RPGLCGPGKCMNTADSY 400 C PN C N C + C C F G C+ + C G GK T + + Sbjct: 154 CRPNPCQNGATCSRHKRRSKFTCACPDQFKGKFCEIGSDDCYVGDGYSYRGKMNRTVNQH 213 Query: 401 KC 406 C Sbjct: 214 AC 215 >AL390197-1|CAH71108.1| 560|Homo sapiens hyaluronan binding protein 2 protein. Length = 560 Score = 61.7 bits (143), Expect = 2e-09 Identities = 33/102 (32%), Positives = 47/102 (46%), Gaps = 10/102 (9%) Frame = +2 Query: 164 NEEKNIMALALEKENVQNCFT------CAPNLCLNNGVCQEALTEHG--YVCLCAPGFGG 319 N+E+N + EN +T C PN C + G C HG + C C F G Sbjct: 50 NQEENTSSTLTHAENPDWYYTEDQADPCQPNPCEHGGDC----LVHGSTFTCSCLAPFSG 105 Query: 320 NNCDRIGESCRPGLCGPGKCMNTADS--YKCACPVTYTGKNC 439 N C ++ +C+ CG G+C+ T Y+C C YTG +C Sbjct: 106 NKCQKVQNTCKDNPCGRGQCLITQSPPYYRCVCKHPYTGPSC 147 Score = 49.6 bits (113), Expect = 7e-06 Identities = 28/84 (33%), Positives = 38/84 (45%), Gaps = 3/84 (3%) Frame = +2 Query: 203 ENVQNCFTCAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLCGPG-KC 379 + VQN TC N C G C + Y C+C + G +C ++ CRP C G C Sbjct: 109 QKVQN--TCKDNPC-GRGQCLITQSPPYYRCVCKHPYTGPSCSQVVPVCRPNPCQNGATC 165 Query: 380 M--NTADSYKCACPVTYTGKNCEV 445 + CACP + GK CE+ Sbjct: 166 SRHKRRSKFTCACPDQFKGKFCEI 189 Score = 35.1 bits (77), Expect = 0.16 Identities = 17/62 (27%), Positives = 22/62 (35%), Gaps = 2/62 (3%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESC--RPGLCGPGKCMNTADSY 400 C PN C N C + C C F G C+ + C G GK T + + Sbjct: 154 CRPNPCQNGATCSRHKRRSKFTCACPDQFKGKFCEIGSDDCYVGDGYSYRGKMNRTVNQH 213 Query: 401 KC 406 C Sbjct: 214 AC 215 >Y14330-1|CAA74706.1| 1223|Homo sapiens jagged2 protein protein. Length = 1223 Score = 61.3 bits (142), Expect = 2e-09 Identities = 28/74 (37%), Positives = 38/74 (51%), Gaps = 1/74 (1%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLCGPG-KCMNTADSYK 403 CA + C + G+C++ G+ C C GF G C+ + C P C G +C N Y Sbjct: 487 CASSPCHSGGLCEDLAD--GFHCHCPQGFSGPLCEVDVDLCEPSPCRNGARCYNLEGDYY 544 Query: 404 CACPVTYTGKNCEV 445 CACP + GKNC V Sbjct: 545 CACPDDFGGKNCSV 558 Score = 59.7 bits (138), Expect = 6e-09 Identities = 25/69 (36%), Positives = 38/69 (55%), Gaps = 1/69 (1%) Frame = +2 Query: 242 CLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLC-GPGKCMNTADSYKCACPV 418 C + G C++ + +GY C+C GFGG +C+ + C C G C + AD + C CP Sbjct: 454 CQHGGTCKDLV--NGYQCVCPRGFGGRHCELERDECASSPCHSGGLCEDLADGFHCHCPQ 511 Query: 419 TYTGKNCEV 445 ++G CEV Sbjct: 512 GFSGPLCEV 520 Score = 56.8 bits (131), Expect = 5e-08 Identities = 25/77 (32%), Positives = 39/77 (50%), Gaps = 1/77 (1%) Frame = +2 Query: 215 NCFTCAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLCGPG-KCMNTA 391 N C P C N G+C + + + + C CAPGF G +C + C+ C G C++ Sbjct: 774 NTNDCNPLPCYNGGICVDGV--NWFRCECAPGFAGPDCRINIDECQSSPCAYGATCVDEI 831 Query: 392 DSYKCACPVTYTGKNCE 442 + Y+C+CP G C+ Sbjct: 832 NGYRCSCPPGRAGPRCQ 848 Score = 55.2 bits (127), Expect = 1e-07 Identities = 25/75 (33%), Positives = 37/75 (49%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLCGPGKCMNTADSYKC 406 C CLN C+ + GY C C PG+ G NC CR G C + + Y+C Sbjct: 412 CEGKPCLNAFSCKNLIG--GYYCDCIPGWKGINCHINVNDCRGQCQHGGTCKDLVNGYQC 469 Query: 407 ACPVTYTGKNCEVKQ 451 CP + G++CE+++ Sbjct: 470 VCPRGFGGRHCELER 484 Score = 52.8 bits (121), Expect = 7e-07 Identities = 28/93 (30%), Positives = 41/93 (44%), Gaps = 1/93 (1%) Frame = +2 Query: 164 NEEKNIMALALEKENVQNCFTCAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGE 343 N E N L +K+ + C + P C N G C A + Y C C G+ G NC++ Sbjct: 278 NCETNWGGLLCDKD-LNYCGSHHP--CTNGGTCINAEPDQ-YRCTCPDGYSGRNCEKAEH 333 Query: 344 SCRPGLC-GPGKCMNTADSYKCACPVTYTGKNC 439 +C C G C ++C CP ++G C Sbjct: 334 ACTSNPCANGGSCHEVPSGFECHCPSGWSGPTC 366 Score = 52.4 bits (120), Expect = 1e-06 Identities = 23/75 (30%), Positives = 34/75 (45%), Gaps = 2/75 (2%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIG-ESCRPGLCGPG-KCMNTADSY 400 C N C N G C E + G+ C C G+ G C + C C G C++ D + Sbjct: 335 CTSNPCANGGSCHEVPS--GFECHCPSGWSGPTCASADIDECASNPCAAGGTCVDQVDGF 392 Query: 401 KCACPVTYTGKNCEV 445 +C CP + G C++ Sbjct: 393 ECICPEQWVGATCQL 407 Score = 51.2 bits (117), Expect = 2e-06 Identities = 22/74 (29%), Positives = 35/74 (47%), Gaps = 1/74 (1%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLCGPG-KCMNTADSYK 403 C P+ C + G C + + + + C C G+ G C C C G C ++ D+++ Sbjct: 663 CLPDPCHSRGRCYDLVND--FYCACDDGWKGKTCHSREFQCDAYTCSNGGTCYDSGDTFR 720 Query: 404 CACPVTYTGKNCEV 445 CACP + G C V Sbjct: 721 CACPPGWKGSTCAV 734 Score = 50.8 bits (116), Expect = 3e-06 Identities = 26/91 (28%), Positives = 40/91 (43%), Gaps = 1/91 (1%) Frame = +2 Query: 212 QNCFTCAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLC-GPGKCMNT 388 +N C C N G C + + + C C G+ G CD C P C G+C + Sbjct: 620 ENIDDCLGQPCRNGGTCIDEVD--AFRCFCPSGWEGELCDTNPNDCLPDPCHSRGRCYDL 677 Query: 389 ADSYKCACPVTYTGKNCEVKQLIEYPAFTGS 481 + + CAC + GK C ++ + A+T S Sbjct: 678 VNDFYCACDDGWKGKTCHSRE-FQCDAYTCS 707 Score = 50.8 bits (116), Expect = 3e-06 Identities = 21/75 (28%), Positives = 35/75 (46%), Gaps = 1/75 (1%) Frame = +2 Query: 224 TCAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLC-GPGKCMNTADSY 400 +C PN C+N G C + + C+C G+ G C C P C G C++ + + Sbjct: 739 SCLPNPCVNGGTC--VGSGASFSCICRDGWEGRTCTHNTNDCNPLPCYNGGICVDGVNWF 796 Query: 401 KCACPVTYTGKNCEV 445 +C C + G +C + Sbjct: 797 RCECAPGFAGPDCRI 811 Score = 45.6 bits (103), Expect = 1e-04 Identities = 28/79 (35%), Positives = 36/79 (45%), Gaps = 4/79 (5%) Frame = +2 Query: 218 CFTCAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESC---RPGLCGPGKCMNT 388 C C P +G C E + C C +GG CD+ C P G G C+N Sbjct: 257 CDECVPYPGCVHGSCVEP-----WQCNCETNWGGLLCDKDLNYCGSHHPCTNG-GTCINA 310 Query: 389 A-DSYKCACPVTYTGKNCE 442 D Y+C CP Y+G+NCE Sbjct: 311 EPDQYRCTCPDGYSGRNCE 329 Score = 45.6 bits (103), Expect = 1e-04 Identities = 24/78 (30%), Positives = 38/78 (48%), Gaps = 5/78 (6%) Frame = +2 Query: 224 TCAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNC-----DRIGESCRPGLCGPGKCMNT 388 T A +C +G C + C+C GF G C D +G+ CR G G C++ Sbjct: 585 TAASGVCGPHGRCVSQ-PGGNFSCICDSGFTGTYCHENIDDCLGQPCRNG----GTCIDE 639 Query: 389 ADSYKCACPVTYTGKNCE 442 D+++C CP + G+ C+ Sbjct: 640 VDAFRCFCPSGWEGELCD 657 Score = 39.1 bits (87), Expect = 0.010 Identities = 18/46 (39%), Positives = 19/46 (41%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLC 364 C P+ C N C E Y C C FGG NC E C G C Sbjct: 525 CEPSPCRNGARCYNL--EGDYYCACPDDFGGKNCSVPREPCPGGAC 568 Score = 30.7 bits (66), Expect = 3.4 Identities = 20/70 (28%), Positives = 25/70 (35%), Gaps = 4/70 (5%) Frame = +2 Query: 215 NCFTCAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRI---GESC-RPGLCGPGKCM 382 N C + C C + + +GY C C PG G C + G SC G P Sbjct: 812 NIDECQSSPCAYGATCVDEI--NGYRCSCPPGRAGPRCQEVIGFGRSCWSRGTPFPHGSS 869 Query: 383 NTADSYKCAC 412 D C C Sbjct: 870 WVEDCNSCRC 879 >AF111170-2|AAD15562.1| 1238|Homo sapiens Jagged2 protein. Length = 1238 Score = 61.3 bits (142), Expect = 2e-09 Identities = 28/74 (37%), Positives = 38/74 (51%), Gaps = 1/74 (1%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLCGPG-KCMNTADSYK 403 CA + C + G+C++ G+ C C GF G C+ + C P C G +C N Y Sbjct: 502 CASSPCHSGGLCEDLAD--GFHCHCPQGFSGPLCEVDVDLCEPSPCRNGARCYNLEGDYY 559 Query: 404 CACPVTYTGKNCEV 445 CACP + GKNC V Sbjct: 560 CACPDDFGGKNCSV 573 Score = 59.7 bits (138), Expect = 6e-09 Identities = 25/69 (36%), Positives = 38/69 (55%), Gaps = 1/69 (1%) Frame = +2 Query: 242 CLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLC-GPGKCMNTADSYKCACPV 418 C + G C++ + +GY C+C GFGG +C+ + C C G C + AD + C CP Sbjct: 469 CQHGGTCKDLV--NGYQCVCPRGFGGRHCELERDECASSPCHSGGLCEDLADGFHCHCPQ 526 Query: 419 TYTGKNCEV 445 ++G CEV Sbjct: 527 GFSGPLCEV 535 Score = 56.8 bits (131), Expect = 5e-08 Identities = 25/77 (32%), Positives = 39/77 (50%), Gaps = 1/77 (1%) Frame = +2 Query: 215 NCFTCAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLCGPG-KCMNTA 391 N C P C N G+C + + + + C CAPGF G +C + C+ C G C++ Sbjct: 789 NTNDCNPLPCYNGGICVDGV--NWFRCECAPGFAGPDCRINIDECQSSPCAYGATCVDEI 846 Query: 392 DSYKCACPVTYTGKNCE 442 + Y+C+CP G C+ Sbjct: 847 NGYRCSCPPGRAGPRCQ 863 Score = 55.2 bits (127), Expect = 1e-07 Identities = 25/75 (33%), Positives = 37/75 (49%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLCGPGKCMNTADSYKC 406 C CLN C+ + GY C C PG+ G NC CR G C + + Y+C Sbjct: 427 CEGKPCLNAFSCKNLIG--GYYCDCIPGWKGINCHINVNDCRGQCQHGGTCKDLVNGYQC 484 Query: 407 ACPVTYTGKNCEVKQ 451 CP + G++CE+++ Sbjct: 485 VCPRGFGGRHCELER 499 Score = 54.4 bits (125), Expect = 2e-07 Identities = 23/74 (31%), Positives = 34/74 (45%), Gaps = 1/74 (1%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLCGPG-KCMNTADSYK 403 C N C N G C E + G+ C C G+ G C + C C G C++ D ++ Sbjct: 351 CTSNPCANGGSCHEVPS--GFECHCPSGWSGPTCALDIDECASNPCAAGGTCVDQVDGFE 408 Query: 404 CACPVTYTGKNCEV 445 C CP + G C++ Sbjct: 409 CICPEQWVGATCQL 422 Score = 52.8 bits (121), Expect = 7e-07 Identities = 28/93 (30%), Positives = 41/93 (44%), Gaps = 1/93 (1%) Frame = +2 Query: 164 NEEKNIMALALEKENVQNCFTCAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGE 343 N E N L +K+ + C + P C N G C A + Y C C G+ G NC++ Sbjct: 294 NCETNWGGLLCDKD-LNYCGSHHP--CTNGGTCINAEPDQ-YRCTCPDGYSGRNCEKAEH 349 Query: 344 SCRPGLC-GPGKCMNTADSYKCACPVTYTGKNC 439 +C C G C ++C CP ++G C Sbjct: 350 ACTSNPCANGGSCHEVPSGFECHCPSGWSGPTC 382 Score = 51.2 bits (117), Expect = 2e-06 Identities = 22/74 (29%), Positives = 35/74 (47%), Gaps = 1/74 (1%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLCGPG-KCMNTADSYK 403 C P+ C + G C + + + + C C G+ G C C C G C ++ D+++ Sbjct: 678 CLPDPCHSRGRCYDLVND--FYCACDDGWKGKTCHSREFQCDAYTCSNGGTCYDSGDTFR 735 Query: 404 CACPVTYTGKNCEV 445 CACP + G C V Sbjct: 736 CACPPGWKGSTCAV 749 Score = 50.8 bits (116), Expect = 3e-06 Identities = 26/91 (28%), Positives = 40/91 (43%), Gaps = 1/91 (1%) Frame = +2 Query: 212 QNCFTCAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLC-GPGKCMNT 388 +N C C N G C + + + C C G+ G CD C P C G+C + Sbjct: 635 ENIDDCLGQPCRNGGTCIDEVD--AFRCFCPSGWEGELCDTNPNDCLPDPCHSRGRCYDL 692 Query: 389 ADSYKCACPVTYTGKNCEVKQLIEYPAFTGS 481 + + CAC + GK C ++ + A+T S Sbjct: 693 VNDFYCACDDGWKGKTCHSRE-FQCDAYTCS 722 Score = 50.8 bits (116), Expect = 3e-06 Identities = 21/75 (28%), Positives = 35/75 (46%), Gaps = 1/75 (1%) Frame = +2 Query: 224 TCAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLC-GPGKCMNTADSY 400 +C PN C+N G C + + C+C G+ G C C P C G C++ + + Sbjct: 754 SCLPNPCVNGGTC--VGSGASFSCICRDGWEGRTCTHNTNDCNPLPCYNGGICVDGVNWF 811 Query: 401 KCACPVTYTGKNCEV 445 +C C + G +C + Sbjct: 812 RCECAPGFAGPDCRI 826 Score = 45.6 bits (103), Expect = 1e-04 Identities = 28/79 (35%), Positives = 36/79 (45%), Gaps = 4/79 (5%) Frame = +2 Query: 218 CFTCAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESC---RPGLCGPGKCMNT 388 C C P +G C E + C C +GG CD+ C P G G C+N Sbjct: 273 CDECVPYPGCVHGSCVEP-----WQCNCETNWGGLLCDKDLNYCGSHHPCTNG-GTCINA 326 Query: 389 A-DSYKCACPVTYTGKNCE 442 D Y+C CP Y+G+NCE Sbjct: 327 EPDQYRCTCPDGYSGRNCE 345 Score = 45.6 bits (103), Expect = 1e-04 Identities = 24/78 (30%), Positives = 38/78 (48%), Gaps = 5/78 (6%) Frame = +2 Query: 224 TCAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNC-----DRIGESCRPGLCGPGKCMNT 388 T A +C +G C + C+C GF G C D +G+ CR G G C++ Sbjct: 600 TAASGVCGPHGRCVSQ-PGGNFSCICDSGFTGTYCHENIDDCLGQPCRNG----GTCIDE 654 Query: 389 ADSYKCACPVTYTGKNCE 442 D+++C CP + G+ C+ Sbjct: 655 VDAFRCFCPSGWEGELCD 672 Score = 39.1 bits (87), Expect = 0.010 Identities = 18/46 (39%), Positives = 19/46 (41%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLC 364 C P+ C N C E Y C C FGG NC E C G C Sbjct: 540 CEPSPCRNGARCYNL--EGDYYCACPDDFGGKNCSVPREPCPGGAC 583 Score = 30.7 bits (66), Expect = 3.4 Identities = 20/70 (28%), Positives = 25/70 (35%), Gaps = 4/70 (5%) Frame = +2 Query: 215 NCFTCAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRI---GESC-RPGLCGPGKCM 382 N C + C C + + +GY C C PG G C + G SC G P Sbjct: 827 NIDECQSSPCAYGATCVDEI--NGYRCSCPPGRAGPRCQEVIGFGRSCWSRGTPFPHGSS 884 Query: 383 NTADSYKCAC 412 D C C Sbjct: 885 WVEDCNSCRC 894 >AF029779-1|AAB84216.1| 1200|Homo sapiens hJAG2.del-E6 protein. Length = 1200 Score = 61.3 bits (142), Expect = 2e-09 Identities = 28/74 (37%), Positives = 38/74 (51%), Gaps = 1/74 (1%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLCGPG-KCMNTADSYK 403 CA + C + G+C++ G+ C C GF G C+ + C P C G +C N Y Sbjct: 464 CASSPCHSGGLCEDLAD--GFHCHCPQGFSGPLCEVDVDLCEPSPCRNGARCYNLEGDYY 521 Query: 404 CACPVTYTGKNCEV 445 CACP + GKNC V Sbjct: 522 CACPDDFGGKNCSV 535 Score = 59.7 bits (138), Expect = 6e-09 Identities = 25/69 (36%), Positives = 38/69 (55%), Gaps = 1/69 (1%) Frame = +2 Query: 242 CLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLC-GPGKCMNTADSYKCACPV 418 C + G C++ + +GY C+C GFGG +C+ + C C G C + AD + C CP Sbjct: 431 CQHGGTCKDLV--NGYQCVCPRGFGGRHCELERDKCASSPCHSGGLCEDLADGFHCHCPQ 488 Query: 419 TYTGKNCEV 445 ++G CEV Sbjct: 489 GFSGPLCEV 497 Score = 56.8 bits (131), Expect = 5e-08 Identities = 25/77 (32%), Positives = 39/77 (50%), Gaps = 1/77 (1%) Frame = +2 Query: 215 NCFTCAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLCGPG-KCMNTA 391 N C P C N G+C + + + + C CAPGF G +C + C+ C G C++ Sbjct: 751 NTNDCNPLPCYNGGICVDGV--NWFRCECAPGFAGPDCRINIDECQSSPCAYGATCVDEI 808 Query: 392 DSYKCACPVTYTGKNCE 442 + Y+C+CP G C+ Sbjct: 809 NGYRCSCPPGRAGPRCQ 825 Score = 52.8 bits (121), Expect = 7e-07 Identities = 28/93 (30%), Positives = 41/93 (44%), Gaps = 1/93 (1%) Frame = +2 Query: 164 NEEKNIMALALEKENVQNCFTCAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGE 343 N E N L +K+ + C + P C N G C A + Y C C G+ G NC++ Sbjct: 294 NCETNWGGLLCDKD-LNYCGSHHP--CTNGGTCINAEPDQ-YRCTCPDGYSGRNCEKAEH 349 Query: 344 SCRPGLC-GPGKCMNTADSYKCACPVTYTGKNC 439 +C C G C ++C CP ++G C Sbjct: 350 ACTSNPCANGGSCHEVPSGFECHCPSGWSGPTC 382 Score = 52.0 bits (119), Expect = 1e-06 Identities = 22/75 (29%), Positives = 36/75 (48%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLCGPGKCMNTADSYKC 406 CA N C G C + + G+ C+C + G C CR G C + + Y+C Sbjct: 389 CASNPCAAGGTCVDQVD--GFECICPEQWVGATCQLDVNDCRGQCQHGGTCKDLVNGYQC 446 Query: 407 ACPVTYTGKNCEVKQ 451 CP + G++CE+++ Sbjct: 447 VCPRGFGGRHCELER 461 Score = 51.2 bits (117), Expect = 2e-06 Identities = 22/74 (29%), Positives = 35/74 (47%), Gaps = 1/74 (1%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLCGPG-KCMNTADSYK 403 C P+ C + G C + + + + C C G+ G C C C G C ++ D+++ Sbjct: 640 CLPDPCHSRGRCYDLVND--FYCACDDGWKGKTCHSREFQCDAYTCSNGGTCYDSGDTFR 697 Query: 404 CACPVTYTGKNCEV 445 CACP + G C V Sbjct: 698 CACPPGWKGSTCAV 711 Score = 50.8 bits (116), Expect = 3e-06 Identities = 26/91 (28%), Positives = 40/91 (43%), Gaps = 1/91 (1%) Frame = +2 Query: 212 QNCFTCAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLC-GPGKCMNT 388 +N C C N G C + + + C C G+ G CD C P C G+C + Sbjct: 597 ENIDDCLGQPCRNGGTCIDEVD--AFRCFCPSGWEGELCDTNPNDCLPDPCHSRGRCYDL 654 Query: 389 ADSYKCACPVTYTGKNCEVKQLIEYPAFTGS 481 + + CAC + GK C ++ + A+T S Sbjct: 655 VNDFYCACDDGWKGKTCHSRE-FQCDAYTCS 684 Score = 50.8 bits (116), Expect = 3e-06 Identities = 21/75 (28%), Positives = 35/75 (46%), Gaps = 1/75 (1%) Frame = +2 Query: 224 TCAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLC-GPGKCMNTADSY 400 +C PN C+N G C + + C+C G+ G C C P C G C++ + + Sbjct: 716 SCLPNPCVNGGTC--VGSGASFSCICRDGWEGRTCTHNTNDCNPLPCYNGGICVDGVNWF 773 Query: 401 KCACPVTYTGKNCEV 445 +C C + G +C + Sbjct: 774 RCECAPGFAGPDCRI 788 Score = 45.6 bits (103), Expect = 1e-04 Identities = 28/79 (35%), Positives = 36/79 (45%), Gaps = 4/79 (5%) Frame = +2 Query: 218 CFTCAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESC---RPGLCGPGKCMNT 388 C C P +G C E + C C +GG CD+ C P G G C+N Sbjct: 273 CDECVPYPGCVHGSCVEP-----WQCNCETNWGGLLCDKDLNYCGSHHPCTNG-GTCINA 326 Query: 389 A-DSYKCACPVTYTGKNCE 442 D Y+C CP Y+G+NCE Sbjct: 327 EPDQYRCTCPDGYSGRNCE 345 Score = 45.6 bits (103), Expect = 1e-04 Identities = 24/78 (30%), Positives = 38/78 (48%), Gaps = 5/78 (6%) Frame = +2 Query: 224 TCAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNC-----DRIGESCRPGLCGPGKCMNT 388 T A +C +G C + C+C GF G C D +G+ CR G G C++ Sbjct: 562 TAASGVCGPHGRCVSQ-PGGNFSCICDSGFTGTYCHENIDDCLGQPCRNG----GTCIDE 616 Query: 389 ADSYKCACPVTYTGKNCE 442 D+++C CP + G+ C+ Sbjct: 617 VDAFRCFCPSGWEGELCD 634 Score = 39.1 bits (87), Expect = 0.010 Identities = 18/46 (39%), Positives = 19/46 (41%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLC 364 C P+ C N C E Y C C FGG NC E C G C Sbjct: 502 CEPSPCRNGARCYNL--EGDYYCACPDDFGGKNCSVPREPCPGGAC 545 Score = 30.7 bits (66), Expect = 3.4 Identities = 20/70 (28%), Positives = 25/70 (35%), Gaps = 4/70 (5%) Frame = +2 Query: 215 NCFTCAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRI---GESC-RPGLCGPGKCM 382 N C + C C + + +GY C C PG G C + G SC G P Sbjct: 789 NIDECQSSPCAYGATCVDEI--NGYRCSCPPGRAGPRCQEVIGFGRSCWSRGTPFPHGSS 846 Query: 383 NTADSYKCAC 412 D C C Sbjct: 847 WVEDCNSCRC 856 >AF029778-1|AAB84215.1| 1238|Homo sapiens Jagged2 protein. Length = 1238 Score = 61.3 bits (142), Expect = 2e-09 Identities = 28/74 (37%), Positives = 38/74 (51%), Gaps = 1/74 (1%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLCGPG-KCMNTADSYK 403 CA + C + G+C++ G+ C C GF G C+ + C P C G +C N Y Sbjct: 502 CASSPCHSGGLCEDLAD--GFHCHCPQGFSGPLCEVDVDLCEPSPCRNGARCYNLEGDYY 559 Query: 404 CACPVTYTGKNCEV 445 CACP + GKNC V Sbjct: 560 CACPDDFGGKNCSV 573 Score = 59.7 bits (138), Expect = 6e-09 Identities = 25/69 (36%), Positives = 38/69 (55%), Gaps = 1/69 (1%) Frame = +2 Query: 242 CLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLC-GPGKCMNTADSYKCACPV 418 C + G C++ + +GY C+C GFGG +C+ + C C G C + AD + C CP Sbjct: 469 CQHGGTCKDLV--NGYQCVCPRGFGGRHCELERDKCASSPCHSGGLCEDLADGFHCHCPQ 526 Query: 419 TYTGKNCEV 445 ++G CEV Sbjct: 527 GFSGPLCEV 535 Score = 56.8 bits (131), Expect = 5e-08 Identities = 25/77 (32%), Positives = 39/77 (50%), Gaps = 1/77 (1%) Frame = +2 Query: 215 NCFTCAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLCGPG-KCMNTA 391 N C P C N G+C + + + + C CAPGF G +C + C+ C G C++ Sbjct: 789 NTNDCNPLPCYNGGICVDGV--NWFRCECAPGFAGPDCRINIDECQSSPCAYGATCVDEI 846 Query: 392 DSYKCACPVTYTGKNCE 442 + Y+C+CP G C+ Sbjct: 847 NGYRCSCPPGRAGPRCQ 863 Score = 55.2 bits (127), Expect = 1e-07 Identities = 25/75 (33%), Positives = 37/75 (49%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLCGPGKCMNTADSYKC 406 C CLN C+ + GY C C PG+ G NC CR G C + + Y+C Sbjct: 427 CEGKPCLNAFSCKNLIG--GYYCDCIPGWKGINCHINVNDCRGQCQHGGTCKDLVNGYQC 484 Query: 407 ACPVTYTGKNCEVKQ 451 CP + G++CE+++ Sbjct: 485 VCPRGFGGRHCELER 499 Score = 54.4 bits (125), Expect = 2e-07 Identities = 23/74 (31%), Positives = 34/74 (45%), Gaps = 1/74 (1%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLCGPG-KCMNTADSYK 403 C N C N G C E + G+ C C G+ G C + C C G C++ D ++ Sbjct: 351 CTSNPCANGGSCHEVPS--GFECHCPSGWSGPTCALDIDECASNPCAAGGTCVDQVDGFE 408 Query: 404 CACPVTYTGKNCEV 445 C CP + G C++ Sbjct: 409 CICPEQWVGATCQL 422 Score = 52.8 bits (121), Expect = 7e-07 Identities = 28/93 (30%), Positives = 41/93 (44%), Gaps = 1/93 (1%) Frame = +2 Query: 164 NEEKNIMALALEKENVQNCFTCAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGE 343 N E N L +K+ + C + P C N G C A + Y C C G+ G NC++ Sbjct: 294 NCETNWGGLLCDKD-LNYCGSHHP--CTNGGTCINAEPDQ-YRCTCPDGYSGRNCEKAEH 349 Query: 344 SCRPGLC-GPGKCMNTADSYKCACPVTYTGKNC 439 +C C G C ++C CP ++G C Sbjct: 350 ACTSNPCANGGSCHEVPSGFECHCPSGWSGPTC 382 Score = 51.2 bits (117), Expect = 2e-06 Identities = 22/74 (29%), Positives = 35/74 (47%), Gaps = 1/74 (1%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLCGPG-KCMNTADSYK 403 C P+ C + G C + + + + C C G+ G C C C G C ++ D+++ Sbjct: 678 CLPDPCHSRGRCYDLVND--FYCACDDGWKGKTCHSREFQCDAYTCSNGGTCYDSGDTFR 735 Query: 404 CACPVTYTGKNCEV 445 CACP + G C V Sbjct: 736 CACPPGWKGSTCAV 749 Score = 50.8 bits (116), Expect = 3e-06 Identities = 26/91 (28%), Positives = 40/91 (43%), Gaps = 1/91 (1%) Frame = +2 Query: 212 QNCFTCAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLC-GPGKCMNT 388 +N C C N G C + + + C C G+ G CD C P C G+C + Sbjct: 635 ENIDDCLGQPCRNGGTCIDEVD--AFRCFCPSGWEGELCDTNPNDCLPDPCHSRGRCYDL 692 Query: 389 ADSYKCACPVTYTGKNCEVKQLIEYPAFTGS 481 + + CAC + GK C ++ + A+T S Sbjct: 693 VNDFYCACDDGWKGKTCHSRE-FQCDAYTCS 722 Score = 50.8 bits (116), Expect = 3e-06 Identities = 21/75 (28%), Positives = 35/75 (46%), Gaps = 1/75 (1%) Frame = +2 Query: 224 TCAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLC-GPGKCMNTADSY 400 +C PN C+N G C + + C+C G+ G C C P C G C++ + + Sbjct: 754 SCLPNPCVNGGTC--VGSGASFSCICRDGWEGRTCTHNTNDCNPLPCYNGGICVDGVNWF 811 Query: 401 KCACPVTYTGKNCEV 445 +C C + G +C + Sbjct: 812 RCECAPGFAGPDCRI 826 Score = 45.6 bits (103), Expect = 1e-04 Identities = 28/79 (35%), Positives = 36/79 (45%), Gaps = 4/79 (5%) Frame = +2 Query: 218 CFTCAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESC---RPGLCGPGKCMNT 388 C C P +G C E + C C +GG CD+ C P G G C+N Sbjct: 273 CDECVPYPGCVHGSCVEP-----WQCNCETNWGGLLCDKDLNYCGSHHPCTNG-GTCINA 326 Query: 389 A-DSYKCACPVTYTGKNCE 442 D Y+C CP Y+G+NCE Sbjct: 327 EPDQYRCTCPDGYSGRNCE 345 Score = 45.6 bits (103), Expect = 1e-04 Identities = 24/78 (30%), Positives = 38/78 (48%), Gaps = 5/78 (6%) Frame = +2 Query: 224 TCAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNC-----DRIGESCRPGLCGPGKCMNT 388 T A +C +G C + C+C GF G C D +G+ CR G G C++ Sbjct: 600 TAASGVCGPHGRCVSQ-PGGNFSCICDSGFTGTYCHENIDDCLGQPCRNG----GTCIDE 654 Query: 389 ADSYKCACPVTYTGKNCE 442 D+++C CP + G+ C+ Sbjct: 655 VDAFRCFCPSGWEGELCD 672 Score = 39.1 bits (87), Expect = 0.010 Identities = 18/46 (39%), Positives = 19/46 (41%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLC 364 C P+ C N C E Y C C FGG NC E C G C Sbjct: 540 CEPSPCRNGARCYNL--EGDYYCACPDDFGGKNCSVPREPCPGGAC 583 Score = 30.7 bits (66), Expect = 3.4 Identities = 20/70 (28%), Positives = 25/70 (35%), Gaps = 4/70 (5%) Frame = +2 Query: 215 NCFTCAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRI---GESC-RPGLCGPGKCM 382 N C + C C + + +GY C C PG G C + G SC G P Sbjct: 827 NIDECQSSPCAYGATCVDEI--NGYRCSCPPGRAGPRCQEVIGFGRSCWSRGTPFPHGSS 884 Query: 383 NTADSYKCAC 412 D C C Sbjct: 885 WVEDCNSCRC 894 >AF020201-1|AAB71189.1| 1238|Homo sapiens Jagged 2 protein. Length = 1238 Score = 61.3 bits (142), Expect = 2e-09 Identities = 28/74 (37%), Positives = 38/74 (51%), Gaps = 1/74 (1%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLCGPG-KCMNTADSYK 403 CA + C + G+C++ G+ C C GF G C+ + C P C G +C N Y Sbjct: 502 CASSPCHSGGLCEDLAD--GFHCHCPQGFSGPLCEVDVDLCEPSPCRNGARCYNLEGDYY 559 Query: 404 CACPVTYTGKNCEV 445 CACP + GKNC V Sbjct: 560 CACPDDFGGKNCSV 573 Score = 59.7 bits (138), Expect = 6e-09 Identities = 25/69 (36%), Positives = 38/69 (55%), Gaps = 1/69 (1%) Frame = +2 Query: 242 CLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLC-GPGKCMNTADSYKCACPV 418 C + G C++ + +GY C+C GFGG +C+ + C C G C + AD + C CP Sbjct: 469 CQHGGTCKDLV--NGYQCVCPRGFGGRHCELERDKCASSPCHSGGLCEDLADGFHCHCPQ 526 Query: 419 TYTGKNCEV 445 ++G CEV Sbjct: 527 GFSGPLCEV 535 Score = 56.8 bits (131), Expect = 5e-08 Identities = 25/77 (32%), Positives = 39/77 (50%), Gaps = 1/77 (1%) Frame = +2 Query: 215 NCFTCAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLCGPG-KCMNTA 391 N C P C N G+C + + + + C CAPGF G +C + C+ C G C++ Sbjct: 789 NTNDCNPLPCYNGGICVDGV--NWFRCECAPGFAGPDCRINIDECQSSPCAYGATCVDEI 846 Query: 392 DSYKCACPVTYTGKNCE 442 + Y+C+CP G C+ Sbjct: 847 NGYRCSCPPGRAGPRCQ 863 Score = 55.2 bits (127), Expect = 1e-07 Identities = 25/75 (33%), Positives = 37/75 (49%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLCGPGKCMNTADSYKC 406 C CLN C+ + GY C C PG+ G NC CR G C + + Y+C Sbjct: 427 CEGKPCLNAFSCKNLIG--GYYCDCIPGWKGINCHINVNDCRGQCQHGGTCKDLVNGYQC 484 Query: 407 ACPVTYTGKNCEVKQ 451 CP + G++CE+++ Sbjct: 485 VCPRGFGGRHCELER 499 Score = 54.4 bits (125), Expect = 2e-07 Identities = 23/74 (31%), Positives = 34/74 (45%), Gaps = 1/74 (1%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLCGPG-KCMNTADSYK 403 C N C N G C E + G+ C C G+ G C + C C G C++ D ++ Sbjct: 351 CTSNPCANGGSCHEVPS--GFECHCPSGWSGPTCALDIDECASNPCAAGGTCVDQVDGFE 408 Query: 404 CACPVTYTGKNCEV 445 C CP + G C++ Sbjct: 409 CICPEQWVGATCQL 422 Score = 52.8 bits (121), Expect = 7e-07 Identities = 28/93 (30%), Positives = 41/93 (44%), Gaps = 1/93 (1%) Frame = +2 Query: 164 NEEKNIMALALEKENVQNCFTCAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGE 343 N E N L +K+ + C + P C N G C A + Y C C G+ G NC++ Sbjct: 294 NCETNWGGLLCDKD-LNYCGSHHP--CTNGGTCINAEPDQ-YRCTCPDGYSGRNCEKAEH 349 Query: 344 SCRPGLC-GPGKCMNTADSYKCACPVTYTGKNC 439 +C C G C ++C CP ++G C Sbjct: 350 ACTSNPCANGGSCHEVPSGFECHCPSGWSGPTC 382 Score = 51.2 bits (117), Expect = 2e-06 Identities = 22/74 (29%), Positives = 35/74 (47%), Gaps = 1/74 (1%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLCGPG-KCMNTADSYK 403 C P+ C + G C + + + + C C G+ G C C C G C ++ D+++ Sbjct: 678 CLPDPCHSRGRCYDLVND--FYCACDDGWKGKTCHSREFQCDAYTCSNGGTCYDSGDTFR 735 Query: 404 CACPVTYTGKNCEV 445 CACP + G C V Sbjct: 736 CACPPGWKGSTCAV 749 Score = 50.8 bits (116), Expect = 3e-06 Identities = 26/91 (28%), Positives = 40/91 (43%), Gaps = 1/91 (1%) Frame = +2 Query: 212 QNCFTCAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLC-GPGKCMNT 388 +N C C N G C + + + C C G+ G CD C P C G+C + Sbjct: 635 ENIDDCLGQPCRNGGTCIDEVD--AFRCFCPSGWEGELCDTNPNDCLPDPCHSRGRCYDL 692 Query: 389 ADSYKCACPVTYTGKNCEVKQLIEYPAFTGS 481 + + CAC + GK C ++ + A+T S Sbjct: 693 VNDFYCACDDGWKGKTCHSRE-FQCDAYTCS 722 Score = 50.8 bits (116), Expect = 3e-06 Identities = 21/75 (28%), Positives = 35/75 (46%), Gaps = 1/75 (1%) Frame = +2 Query: 224 TCAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLC-GPGKCMNTADSY 400 +C PN C+N G C + + C+C G+ G C C P C G C++ + + Sbjct: 754 SCLPNPCVNGGTC--VGSGASFSCICRDGWEGRTCTHNTNDCNPLPCYNGGICVDGVNWF 811 Query: 401 KCACPVTYTGKNCEV 445 +C C + G +C + Sbjct: 812 RCECAPGFAGPDCRI 826 Score = 45.6 bits (103), Expect = 1e-04 Identities = 28/79 (35%), Positives = 36/79 (45%), Gaps = 4/79 (5%) Frame = +2 Query: 218 CFTCAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESC---RPGLCGPGKCMNT 388 C C P +G C E + C C +GG CD+ C P G G C+N Sbjct: 273 CDECVPYPGCVHGSCVEP-----WQCNCETNWGGLLCDKDLNYCGSHHPCTNG-GTCINA 326 Query: 389 A-DSYKCACPVTYTGKNCE 442 D Y+C CP Y+G+NCE Sbjct: 327 EPDQYRCTCPDGYSGRNCE 345 Score = 45.6 bits (103), Expect = 1e-04 Identities = 24/78 (30%), Positives = 38/78 (48%), Gaps = 5/78 (6%) Frame = +2 Query: 224 TCAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNC-----DRIGESCRPGLCGPGKCMNT 388 T A +C +G C + C+C GF G C D +G+ CR G G C++ Sbjct: 600 TAASGVCGPHGRCVSQ-PGGNFSCICDSGFTGTYCHENIDDCLGQPCRNG----GTCIDE 654 Query: 389 ADSYKCACPVTYTGKNCE 442 D+++C CP + G+ C+ Sbjct: 655 VDAFRCFCPSGWEGELCD 672 Score = 39.1 bits (87), Expect = 0.010 Identities = 18/46 (39%), Positives = 19/46 (41%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLC 364 C P+ C N C E Y C C FGG NC E C G C Sbjct: 540 CEPSPCRNGARCYNL--EGDYYCACPDDFGGKNCSVPREPCPGGAC 583 Score = 30.7 bits (66), Expect = 3.4 Identities = 20/70 (28%), Positives = 25/70 (35%), Gaps = 4/70 (5%) Frame = +2 Query: 215 NCFTCAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRI---GESC-RPGLCGPGKCM 382 N C + C C + + +GY C C PG G C + G SC G P Sbjct: 827 NIDECQSSPCAYGATCVDEI--NGYRCSCPPGRAGPRCQEVIGFGRSCWSRGTPFPHGSS 884 Query: 383 NTADSYKCAC 412 D C C Sbjct: 885 WVEDCNSCRC 894 >AF003521-1|AAB61285.1| 1238|Homo sapiens Jagged 2 protein. Length = 1238 Score = 61.3 bits (142), Expect = 2e-09 Identities = 28/74 (37%), Positives = 38/74 (51%), Gaps = 1/74 (1%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLCGPG-KCMNTADSYK 403 CA + C + G+C++ G+ C C GF G C+ + C P C G +C N Y Sbjct: 502 CASSPCHSGGLCEDLAD--GFHCHCPQGFSGPLCEVDVDLCEPSPCRNGARCYNLEGDYY 559 Query: 404 CACPVTYTGKNCEV 445 CACP + GKNC V Sbjct: 560 CACPDDFGGKNCSV 573 Score = 59.7 bits (138), Expect = 6e-09 Identities = 25/69 (36%), Positives = 38/69 (55%), Gaps = 1/69 (1%) Frame = +2 Query: 242 CLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLC-GPGKCMNTADSYKCACPV 418 C + G C++ + +GY C+C GFGG +C+ + C C G C + AD + C CP Sbjct: 469 CQHGGTCKDLV--NGYQCVCPRGFGGRHCELERDKCASSPCHSGGLCEDLADGFHCHCPQ 526 Query: 419 TYTGKNCEV 445 ++G CEV Sbjct: 527 GFSGPLCEV 535 Score = 56.8 bits (131), Expect = 5e-08 Identities = 25/77 (32%), Positives = 39/77 (50%), Gaps = 1/77 (1%) Frame = +2 Query: 215 NCFTCAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLCGPG-KCMNTA 391 N C P C N G+C + + + + C CAPGF G +C + C+ C G C++ Sbjct: 789 NTNDCNPLPCYNGGICVDGV--NWFRCECAPGFAGPDCRINIDECQSSPCAYGATCVDEI 846 Query: 392 DSYKCACPVTYTGKNCE 442 + Y+C+CP G C+ Sbjct: 847 NGYRCSCPPGRAGPRCQ 863 Score = 55.2 bits (127), Expect = 1e-07 Identities = 25/75 (33%), Positives = 37/75 (49%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLCGPGKCMNTADSYKC 406 C CLN C+ + GY C C PG+ G NC CR G C + + Y+C Sbjct: 427 CEGKPCLNAFSCKNLIG--GYYCDCIPGWKGINCHINVNDCRGQCQHGGTCKDLVNGYQC 484 Query: 407 ACPVTYTGKNCEVKQ 451 CP + G++CE+++ Sbjct: 485 VCPRGFGGRHCELER 499 Score = 54.4 bits (125), Expect = 2e-07 Identities = 23/74 (31%), Positives = 34/74 (45%), Gaps = 1/74 (1%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLCGPG-KCMNTADSYK 403 C N C N G C E + G+ C C G+ G C + C C G C++ D ++ Sbjct: 351 CTSNPCANGGSCHEVPS--GFECHCPSGWSGPTCALDIDECASNPCAAGGTCVDQVDGFE 408 Query: 404 CACPVTYTGKNCEV 445 C CP + G C++ Sbjct: 409 CICPEQWVGATCQL 422 Score = 52.8 bits (121), Expect = 7e-07 Identities = 28/93 (30%), Positives = 41/93 (44%), Gaps = 1/93 (1%) Frame = +2 Query: 164 NEEKNIMALALEKENVQNCFTCAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGE 343 N E N L +K+ + C + P C N G C A + Y C C G+ G NC++ Sbjct: 294 NCETNWGGLLCDKD-LNYCGSHHP--CTNGGTCINAEPDQ-YRCTCPDGYSGRNCEKAEH 349 Query: 344 SCRPGLC-GPGKCMNTADSYKCACPVTYTGKNC 439 +C C G C ++C CP ++G C Sbjct: 350 ACTSNPCANGGSCHEVPSGFECHCPSGWSGPTC 382 Score = 51.2 bits (117), Expect = 2e-06 Identities = 22/74 (29%), Positives = 35/74 (47%), Gaps = 1/74 (1%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLCGPG-KCMNTADSYK 403 C P+ C + G C + + + + C C G+ G C C C G C ++ D+++ Sbjct: 678 CLPDPCHSRGRCYDLVND--FYCACDDGWKGKTCHSREFQCDAYTCSNGGTCYDSGDTFR 735 Query: 404 CACPVTYTGKNCEV 445 CACP + G C V Sbjct: 736 CACPPGWKGSTCAV 749 Score = 50.8 bits (116), Expect = 3e-06 Identities = 26/91 (28%), Positives = 40/91 (43%), Gaps = 1/91 (1%) Frame = +2 Query: 212 QNCFTCAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLC-GPGKCMNT 388 +N C C N G C + + + C C G+ G CD C P C G+C + Sbjct: 635 ENIDDCLGQPCRNGGTCIDEVD--AFRCFCPSGWEGELCDTNPNDCLPDPCHSRGRCYDL 692 Query: 389 ADSYKCACPVTYTGKNCEVKQLIEYPAFTGS 481 + + CAC + GK C ++ + A+T S Sbjct: 693 VNDFYCACDDGWKGKTCHSRE-FQCDAYTCS 722 Score = 50.8 bits (116), Expect = 3e-06 Identities = 21/75 (28%), Positives = 35/75 (46%), Gaps = 1/75 (1%) Frame = +2 Query: 224 TCAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLC-GPGKCMNTADSY 400 +C PN C+N G C + + C+C G+ G C C P C G C++ + + Sbjct: 754 SCLPNPCVNGGTC--VGSGASFSCICRDGWEGRTCTHNTNDCNPLPCYNGGICVDGVNWF 811 Query: 401 KCACPVTYTGKNCEV 445 +C C + G +C + Sbjct: 812 RCECAPGFAGPDCRI 826 Score = 45.6 bits (103), Expect = 1e-04 Identities = 28/79 (35%), Positives = 36/79 (45%), Gaps = 4/79 (5%) Frame = +2 Query: 218 CFTCAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESC---RPGLCGPGKCMNT 388 C C P +G C E + C C +GG CD+ C P G G C+N Sbjct: 273 CDECVPYPGCVHGSCVEP-----WQCNCETNWGGLLCDKDLNYCGSHHPCTNG-GTCINA 326 Query: 389 A-DSYKCACPVTYTGKNCE 442 D Y+C CP Y+G+NCE Sbjct: 327 EPDQYRCTCPDGYSGRNCE 345 Score = 45.6 bits (103), Expect = 1e-04 Identities = 24/78 (30%), Positives = 38/78 (48%), Gaps = 5/78 (6%) Frame = +2 Query: 224 TCAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNC-----DRIGESCRPGLCGPGKCMNT 388 T A +C +G C + C+C GF G C D +G+ CR G G C++ Sbjct: 600 TAASGVCGPHGRCVSQ-PGGNFSCICDSGFTGTYCHENIDDCLGQPCRNG----GTCIDE 654 Query: 389 ADSYKCACPVTYTGKNCE 442 D+++C CP + G+ C+ Sbjct: 655 VDAFRCFCPSGWEGELCD 672 Score = 39.1 bits (87), Expect = 0.010 Identities = 18/46 (39%), Positives = 19/46 (41%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLC 364 C P+ C N C E Y C C FGG NC E C G C Sbjct: 540 CEPSPCRNGARCYNL--EGDYYCACPDDFGGKNCSVPREPCPGGAC 583 Score = 30.7 bits (66), Expect = 3.4 Identities = 20/70 (28%), Positives = 25/70 (35%), Gaps = 4/70 (5%) Frame = +2 Query: 215 NCFTCAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRI---GESC-RPGLCGPGKCM 382 N C + C C + + +GY C C PG G C + G SC G P Sbjct: 827 NIDECQSSPCAYGATCVDEI--NGYRCSCPPGRAGPRCQEVIGFGRSCWSRGTPFPHGSS 884 Query: 383 NTADSYKCAC 412 D C C Sbjct: 885 WVEDCNSCRC 894 >BC053656-1|AAH53656.1| 470|Homo sapiens EDIL3 protein protein. Length = 470 Score = 60.9 bits (141), Expect = 3e-09 Identities = 31/80 (38%), Positives = 38/80 (47%), Gaps = 6/80 (7%) Frame = +2 Query: 227 CAPNLCLNNGVCQ--EAL---TEHGYVCLCAPGFGGNNCDRIGESCRPGLC-GPGKCMNT 388 C PN C N G C+ EA T GYVC C GF G +C C C G C + Sbjct: 68 CTPNPCHNGGTCEISEAYRGDTFIGYVCKCPRGFNGIHCQHNINECEVEPCKNGGICTDL 127 Query: 389 ADSYKCACPVTYTGKNCEVK 448 +Y C CP + G+NC+ K Sbjct: 128 VANYSCECPGEFMGRNCQYK 147 Score = 51.2 bits (117), Expect = 2e-06 Identities = 25/82 (30%), Positives = 36/82 (43%), Gaps = 10/82 (12%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGE--SCRPGLCGPGKCMNTADSY 400 C PN C N G+C L + + C C GF NC + E C P C G +++Y Sbjct: 26 CDPNPCENGGICLPGLADGSFSCECPDGFTDPNCSSVVEVGPCTPNPCHNGGTCEISEAY 85 Query: 401 K--------CACPVTYTGKNCE 442 + C CP + G +C+ Sbjct: 86 RGDTFIGYVCKCPRGFNGIHCQ 107 >BC035009-1|AAH35009.1| 737|Homo sapiens delta/notch-like EGF repeat containing protein. Length = 737 Score = 60.5 bits (140), Expect = 4e-09 Identities = 27/72 (37%), Positives = 35/72 (48%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLCGPGKCMNTADSYKC 406 CA + C NNG C + + C C+PGF G C ++ + C C G C + SYKC Sbjct: 434 CASSPCQNNGTCY--VDGVHFTCNCSPGFTGPTCAQLIDFCALSPCAHGTCRSVGTSYKC 491 Query: 407 ACPVTYTGKNCE 442 C Y G CE Sbjct: 492 LCDPGYHGLYCE 503 Score = 58.0 bits (134), Expect = 2e-08 Identities = 28/74 (37%), Positives = 37/74 (50%), Gaps = 1/74 (1%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLCGPG-KCMNTADSYK 403 CA CLN C ++ +G C+CAPGF G CD C C G C++ + Y Sbjct: 547 CANVSCLNGATC-DSDGLNG-TCICAPGFTGEECDIDINECDSNPCHHGGSCLDQPNGYN 604 Query: 404 CACPVTYTGKNCEV 445 C CP + G NCE+ Sbjct: 605 CHCPHGWVGANCEI 618 Score = 54.8 bits (126), Expect = 2e-07 Identities = 30/86 (34%), Positives = 36/86 (41%), Gaps = 14/86 (16%) Frame = +2 Query: 227 CAPNLCLNNGVCQ---EALTEH-------GYVCLCAPGFGGNNCDRIGESCRPGLCGPGK 376 CA C N GVC E +H GY C C G G NC + + C C G Sbjct: 48 CAAQPCRNGGVCTSRPEPDPQHPAPAGEPGYSCTCPAGISGANCQLVADPCASNPCHHGN 107 Query: 377 C----MNTADSYKCACPVTYTGKNCE 442 C +++D Y C C Y G NCE Sbjct: 108 CSSSSSSSSDGYLCICNEGYEGPNCE 133 Score = 49.2 bits (112), Expect = 9e-06 Identities = 24/74 (32%), Positives = 34/74 (45%), Gaps = 1/74 (1%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLC-GPGKCMNTADSYK 403 CA + C + G C+ T Y CLC PG+ G C+ C C C + + Y+ Sbjct: 472 CALSPCAH-GTCRSVGTS--YKCLCDPGYHGLYCEEEYNECLSAPCLNAATCRDLVNGYE 528 Query: 404 CACPVTYTGKNCEV 445 C C Y G +CE+ Sbjct: 529 CVCLAEYKGTHCEL 542 Score = 48.4 bits (110), Expect = 2e-05 Identities = 24/78 (30%), Positives = 34/78 (43%), Gaps = 4/78 (5%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEH---GYVCLCAPGFGGNNCDRIGESCRPGLCGPGK-CMNTAD 394 C C NN C +A + + C+C PG+ G C + C C G C+++ Sbjct: 353 CQRKPCQNNASCIDANEKQDGSNFTCVCLPGYTGELCQSKIDYCILDPCRNGATCISSLS 412 Query: 395 SYKCACPVTYTGKNCEVK 448 + C CP Y G CE K Sbjct: 413 GFTCQCPEGYFGSACEEK 430 Score = 43.6 bits (98), Expect = 4e-04 Identities = 20/74 (27%), Positives = 35/74 (47%), Gaps = 1/74 (1%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLCGPG-KCMNTADSYK 403 C CLN C++ + +GY C+C + G +C+ + C C G C + + Sbjct: 509 CLSAPCLNAATCRDLV--NGYECVCLAEYKGTHCELYKDPCANVSCLNGATCDSDGLNGT 566 Query: 404 CACPVTYTGKNCEV 445 C C +TG+ C++ Sbjct: 567 CICAPGFTGEECDI 580 Score = 33.5 bits (73), Expect = 0.48 Identities = 14/38 (36%), Positives = 23/38 (60%), Gaps = 2/38 (5%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEH--GYVCLCAPGFGGNNCDR 334 CA N C ++G C + + GY+C+C G+ G NC++ Sbjct: 98 CASNPC-HHGNCSSSSSSSSDGYLCICNEGYEGPNCEQ 134 Score = 32.7 bits (71), Expect = 0.84 Identities = 35/135 (25%), Positives = 51/135 (37%), Gaps = 23/135 (17%) Frame = +2 Query: 113 LAGASGFVGCISMLILGNEE----------KNIMALALEKENVQNCFTCAPNL------- 241 L + G V ML LGN K+I+AL L V TC P Sbjct: 261 LQASGGLVLLEEMLALGNNHFIGFVNDSVTKSIVALRLTL--VVKVSTCVPGESHANDLE 318 Query: 242 CLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLC-GPGKCMNT-----ADSYK 403 C G C +E + C C + G C+ ++C+ C C++ ++ Sbjct: 319 CSGKGKCTTKPSEATFSCTCEEQYVGTFCEEY-DACQRKPCQNNASCIDANEKQDGSNFT 377 Query: 404 CACPVTYTGKNCEVK 448 C C YTG+ C+ K Sbjct: 378 CVCLPGYTGELCQSK 392 >BC024766-1|AAH24766.2| 454|Homo sapiens DNER protein protein. Length = 454 Score = 60.5 bits (140), Expect = 4e-09 Identities = 27/72 (37%), Positives = 35/72 (48%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLCGPGKCMNTADSYKC 406 CA + C NNG C + + C C+PGF G C ++ + C C G C + SYKC Sbjct: 151 CASSPCQNNGTCY--VDGVHFTCNCSPGFTGPTCAQLIDFCALSPCAHGTCRSVGTSYKC 208 Query: 407 ACPVTYTGKNCE 442 C Y G CE Sbjct: 209 LCDPGYHGLYCE 220 Score = 58.0 bits (134), Expect = 2e-08 Identities = 28/74 (37%), Positives = 37/74 (50%), Gaps = 1/74 (1%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLCGPG-KCMNTADSYK 403 CA CLN C ++ +G C+CAPGF G CD C C G C++ + Y Sbjct: 264 CANVSCLNGATC-DSDGLNG-TCICAPGFTGEECDIDINECDSNPCHHGGSCLDQPNGYN 321 Query: 404 CACPVTYTGKNCEV 445 C CP + G NCE+ Sbjct: 322 CHCPHGWVGANCEI 335 Score = 49.2 bits (112), Expect = 9e-06 Identities = 24/74 (32%), Positives = 34/74 (45%), Gaps = 1/74 (1%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLC-GPGKCMNTADSYK 403 CA + C + G C+ T Y CLC PG+ G C+ C C C + + Y+ Sbjct: 189 CALSPCAH-GTCRSVGTS--YKCLCDPGYHGLYCEEEYNECLSAPCLNAATCRDLVNGYE 245 Query: 404 CACPVTYTGKNCEV 445 C C Y G +CE+ Sbjct: 246 CVCLAEYKGTHCEL 259 Score = 48.4 bits (110), Expect = 2e-05 Identities = 24/78 (30%), Positives = 34/78 (43%), Gaps = 4/78 (5%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEH---GYVCLCAPGFGGNNCDRIGESCRPGLCGPGK-CMNTAD 394 C C NN C +A + + C+C PG+ G C + C C G C+++ Sbjct: 70 CQRKPCQNNASCIDANEKQDGSNFTCVCLPGYTGELCQSKIDYCILDPCRNGATCISSLS 129 Query: 395 SYKCACPVTYTGKNCEVK 448 + C CP Y G CE K Sbjct: 130 GFTCQCPEGYFGSACEEK 147 Score = 43.6 bits (98), Expect = 4e-04 Identities = 20/74 (27%), Positives = 35/74 (47%), Gaps = 1/74 (1%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLCGPG-KCMNTADSYK 403 C CLN C++ + +GY C+C + G +C+ + C C G C + + Sbjct: 226 CLSAPCLNAATCRDLV--NGYECVCLAEYKGTHCELYKDPCANVSCLNGATCDSDGLNGT 283 Query: 404 CACPVTYTGKNCEV 445 C C +TG+ C++ Sbjct: 284 CICAPGFTGEECDI 297 Score = 32.3 bits (70), Expect = 1.1 Identities = 18/75 (24%), Positives = 31/75 (41%), Gaps = 6/75 (8%) Frame = +2 Query: 242 CLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLC-GPGKCMNT-----ADSYK 403 C G C +E + C C + G C+ ++C+ C C++ ++ Sbjct: 36 CSGKGKCTTKPSEATFSCTCEEQYVGTFCEEY-DACQRKPCQNNASCIDANEKQDGSNFT 94 Query: 404 CACPVTYTGKNCEVK 448 C C YTG+ C+ K Sbjct: 95 CVCLPGYTGELCQSK 109 >AY720432-1|AAU14134.1| 1285|Homo sapiens crumbs-like protein 2 precursor protein. Length = 1285 Score = 60.5 bits (140), Expect = 4e-09 Identities = 27/75 (36%), Positives = 38/75 (50%), Gaps = 1/75 (1%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLC-GPGKCMNTADSYK 403 CA CLN G CQ+ +G+ C C G+ G C+ + C C G C +T Y Sbjct: 324 CASRPCLNGGHCQDL--PNGFQCHCPDGYAGPTCEEDVDECLSDPCLHGGTCSDTVAGYI 381 Query: 404 CACPVTYTGKNCEVK 448 C CP T+ G++C V+ Sbjct: 382 CRCPETWGGRDCSVQ 396 Score = 59.3 bits (137), Expect = 8e-09 Identities = 27/76 (35%), Positives = 37/76 (48%), Gaps = 2/76 (2%) Frame = +2 Query: 227 CAPNLCLNNGVC-QEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLCGPGK-CMNTADSY 400 CA C + +C + G+ C C PGF G C+ + C C G C N AD Y Sbjct: 71 CATQPCHHGALCVPQGPDPTGFRCYCVPGFQGPRCELDIDECASRPCHHGATCRNLADRY 130 Query: 401 KCACPVTYTGKNCEVK 448 +C CP+ Y G CE++ Sbjct: 131 ECHCPLGYAGVTCEME 146 Score = 58.8 bits (136), Expect = 1e-08 Identities = 23/74 (31%), Positives = 37/74 (50%), Gaps = 1/74 (1%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLCGPGKCMNTADS-YK 403 CAP+ CL++G C++ + C C PG+ G C+ + C C G+C D ++ Sbjct: 1060 CAPSPCLHDGACRDLFD--AFACACGPGWEGPRCEAHVDPCHSAPCARGRCHTHPDGRFE 1117 Query: 404 CACPVTYTGKNCEV 445 C CP + G C + Sbjct: 1118 CRCPPGFGGPRCRL 1131 Score = 54.0 bits (124), Expect = 3e-07 Identities = 26/80 (32%), Positives = 43/80 (53%), Gaps = 2/80 (2%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLCG-PGKCMNTADSYK 403 CA CL+ G C + + + C+CAPG+GG C + C+ C G C + + ++ Sbjct: 150 CASAPCLHGGSCLDGVGS--FRCVCAPGYGGTRCQLDLDECQSQPCAHGGTCHDLVNGFR 207 Query: 404 CACPVT-YTGKNCEVKQLIE 460 C C T Y G +CE ++++E Sbjct: 208 CDCAGTGYEGTHCE-REVLE 226 Score = 48.8 bits (111), Expect = 1e-05 Identities = 25/69 (36%), Positives = 35/69 (50%), Gaps = 4/69 (5%) Frame = +2 Query: 284 GYVCLCAPGFGGNNCDRIGESC--RPGLCGPGKCMNTADSYKCACPVTYTGKNCE--VKQ 451 G++C C PGF G +C + C RP L G G C + + ++C CP Y G CE V + Sbjct: 303 GFLCHCPPGFEGADCGVEVDECASRPCLNG-GHCQDLPNGFQCHCPDGYAGPTCEEDVDE 361 Query: 452 LIEYPAFTG 478 + P G Sbjct: 362 CLSDPCLHG 370 Score = 46.4 bits (105), Expect = 6e-05 Identities = 23/77 (29%), Positives = 37/77 (48%), Gaps = 2/77 (2%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCA-PGFGGNNCDRIGESCRPGLCGPG-KCMNTADSY 400 C C + G C + + +G+ C CA G+ G +C+R C C C+ S+ Sbjct: 188 CQSQPCAHGGTCHDLV--NGFRCDCAGTGYEGTHCEREVLECASAPCEHNASCLEGLGSF 245 Query: 401 KCACPVTYTGKNCEVKQ 451 +C C Y+G+ CEV + Sbjct: 246 RCLCWPGYSGELCEVDE 262 Score = 39.9 bits (89), Expect = 0.006 Identities = 22/76 (28%), Positives = 32/76 (42%), Gaps = 5/76 (6%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLCG-PGKCM----NTA 391 C + CL+ G C + + GY+C C +GG +C C+ C C+ + Sbjct: 362 CLSDPCLHGGTCSDTVA--GYICRCPETWGGRDCSVQLTGCQGHTCPLAATCIPIFESGV 419 Query: 392 DSYKCACPVTYTGKNC 439 SY C CP G C Sbjct: 420 HSYVCHCPPGTHGPFC 435 Score = 38.3 bits (85), Expect = 0.017 Identities = 19/57 (33%), Positives = 27/57 (47%), Gaps = 1/57 (1%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLC-GPGKCMNTAD 394 CA C +N C E L + CLC PG+ G C+ + C C G+C+ +D Sbjct: 227 CASAPCEHNASCLEGLGS--FRCLCWPGYSGELCEVDEDECASSPCQHGGRCLQRSD 281 Score = 37.9 bits (84), Expect = 0.022 Identities = 20/70 (28%), Positives = 29/70 (41%), Gaps = 4/70 (5%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDR----IGESCRPGLCGPGKCMNTAD 394 C+P+ C N G C +T + + C C F G C + G+ C P P C D Sbjct: 811 CSPDPCFNGGTC--LVTWNDFHCTCPANFTGPTCAQQLWCPGQPCLP----PATCEEVPD 864 Query: 395 SYKCACPVTY 424 + C T+ Sbjct: 865 GFVCVAEATF 874 Score = 35.9 bits (79), Expect = 0.090 Identities = 21/82 (25%), Positives = 31/82 (37%), Gaps = 2/82 (2%) Frame = +2 Query: 227 CAPNL-CLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLC-GPGKCMNTADSY 400 C+ N+ CL+ C+ C C G G C C C G C Sbjct: 1138 CSLNVTCLDGSPCEGGSPAAN--CSCLEGLAGQRCQVPTLPCEANPCLNGGTCRAAGGVS 1195 Query: 401 KCACPVTYTGKNCEVKQLIEYP 466 +C C ++G+ CEV + + P Sbjct: 1196 ECICNARFSGQFCEVAKGLPLP 1217 Score = 33.5 bits (73), Expect = 0.48 Identities = 12/34 (35%), Positives = 17/34 (50%), Gaps = 1/34 (2%) Frame = +2 Query: 341 ESCRPGLC-GPGKCMNTADSYKCACPVTYTGKNC 439 + C P C G C+ T + + C CP +TG C Sbjct: 809 DMCSPDPCFNGGTCLVTWNDFHCTCPANFTGPTC 842 >AY358891-1|AAQ89250.1| 737|Homo sapiens QPRR262 protein. Length = 737 Score = 60.5 bits (140), Expect = 4e-09 Identities = 27/72 (37%), Positives = 35/72 (48%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLCGPGKCMNTADSYKC 406 CA + C NNG C + + C C+PGF G C ++ + C C G C + SYKC Sbjct: 434 CASSPCQNNGTCY--VDGVHFTCNCSPGFTGPTCAQLIDFCALSPCAHGTCRSVGTSYKC 491 Query: 407 ACPVTYTGKNCE 442 C Y G CE Sbjct: 492 LCDPGYHGLYCE 503 Score = 58.0 bits (134), Expect = 2e-08 Identities = 28/74 (37%), Positives = 37/74 (50%), Gaps = 1/74 (1%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLCGPG-KCMNTADSYK 403 CA CLN C ++ +G C+CAPGF G CD C C G C++ + Y Sbjct: 547 CANVSCLNGATC-DSDGLNG-TCICAPGFTGEECDIDINECDSNPCHHGGSCLDQPNGYN 604 Query: 404 CACPVTYTGKNCEV 445 C CP + G NCE+ Sbjct: 605 CHCPHGWVGANCEI 618 Score = 54.8 bits (126), Expect = 2e-07 Identities = 30/86 (34%), Positives = 36/86 (41%), Gaps = 14/86 (16%) Frame = +2 Query: 227 CAPNLCLNNGVCQ---EALTEH-------GYVCLCAPGFGGNNCDRIGESCRPGLCGPGK 376 CA C N GVC E +H GY C C G G NC + + C C G Sbjct: 48 CAAQPCRNGGVCTSRPEPDPQHPAPAGEPGYSCTCPAGISGANCQLVADPCASNPCHHGN 107 Query: 377 C----MNTADSYKCACPVTYTGKNCE 442 C +++D Y C C Y G NCE Sbjct: 108 CSSSSSSSSDGYLCICNEGYEGPNCE 133 Score = 49.2 bits (112), Expect = 9e-06 Identities = 24/74 (32%), Positives = 34/74 (45%), Gaps = 1/74 (1%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLC-GPGKCMNTADSYK 403 CA + C + G C+ T Y CLC PG+ G C+ C C C + + Y+ Sbjct: 472 CALSPCAH-GTCRSVGTS--YKCLCDPGYHGLYCEEEYNECLSAPCLNAATCRDLVNGYE 528 Query: 404 CACPVTYTGKNCEV 445 C C Y G +CE+ Sbjct: 529 CVCLAEYKGTHCEL 542 Score = 48.4 bits (110), Expect = 2e-05 Identities = 24/78 (30%), Positives = 34/78 (43%), Gaps = 4/78 (5%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEH---GYVCLCAPGFGGNNCDRIGESCRPGLCGPGK-CMNTAD 394 C C NN C +A + + C+C PG+ G C + C C G C+++ Sbjct: 353 CQRKPCQNNASCIDANEKQDGSNFTCVCLPGYTGELCQSKIDYCILDPCRNGATCISSLS 412 Query: 395 SYKCACPVTYTGKNCEVK 448 + C CP Y G CE K Sbjct: 413 GFTCQCPEGYFGSACEEK 430 Score = 43.6 bits (98), Expect = 4e-04 Identities = 20/74 (27%), Positives = 35/74 (47%), Gaps = 1/74 (1%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLCGPG-KCMNTADSYK 403 C CLN C++ + +GY C+C + G +C+ + C C G C + + Sbjct: 509 CLSAPCLNAATCRDLV--NGYECVCLAEYKGTHCELYKDPCANVSCLNGATCDSDGLNGT 566 Query: 404 CACPVTYTGKNCEV 445 C C +TG+ C++ Sbjct: 567 CICAPGFTGEECDI 580 Score = 33.5 bits (73), Expect = 0.48 Identities = 14/38 (36%), Positives = 23/38 (60%), Gaps = 2/38 (5%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEH--GYVCLCAPGFGGNNCDR 334 CA N C ++G C + + GY+C+C G+ G NC++ Sbjct: 98 CASNPC-HHGNCSSSSSSSSDGYLCICNEGYEGPNCEQ 134 Score = 32.7 bits (71), Expect = 0.84 Identities = 35/135 (25%), Positives = 51/135 (37%), Gaps = 23/135 (17%) Frame = +2 Query: 113 LAGASGFVGCISMLILGNEE----------KNIMALALEKENVQNCFTCAPNL------- 241 L + G V ML LGN K+I+AL L V TC P Sbjct: 261 LQASGGLVLLEEMLALGNNHFIGFVNDSVTKSIVALRLTL--VVKVSTCVPGESHANDLE 318 Query: 242 CLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLC-GPGKCMNT-----ADSYK 403 C G C +E + C C + G C+ ++C+ C C++ ++ Sbjct: 319 CSGKGKCTTKPSEATFSCTCEEQYVGTFCEEY-DACQRKPCQNNASCIDANEKQDGSNFT 377 Query: 404 CACPVTYTGKNCEVK 448 C C YTG+ C+ K Sbjct: 378 CVCLPGYTGELCQSK 392 >AL445489-4|CAI39793.1| 1285|Homo sapiens crumbs homolog 2 (Drosophila) protein. Length = 1285 Score = 60.5 bits (140), Expect = 4e-09 Identities = 27/75 (36%), Positives = 38/75 (50%), Gaps = 1/75 (1%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLC-GPGKCMNTADSYK 403 CA CLN G CQ+ +G+ C C G+ G C+ + C C G C +T Y Sbjct: 324 CASRPCLNGGHCQDL--PNGFQCHCPDGYAGPTCEEDVDECLSDPCLHGGTCSDTVAGYI 381 Query: 404 CACPVTYTGKNCEVK 448 C CP T+ G++C V+ Sbjct: 382 CRCPETWGGRDCSVQ 396 Score = 59.3 bits (137), Expect = 8e-09 Identities = 27/76 (35%), Positives = 37/76 (48%), Gaps = 2/76 (2%) Frame = +2 Query: 227 CAPNLCLNNGVC-QEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLCGPGK-CMNTADSY 400 CA C + +C + G+ C C PGF G C+ + C C G C N AD Y Sbjct: 71 CATQPCHHGALCVPQGPDPTGFRCYCVPGFQGPRCELDIDECASRPCHHGATCRNLADRY 130 Query: 401 KCACPVTYTGKNCEVK 448 +C CP+ Y G CE++ Sbjct: 131 ECHCPLGYAGVTCEME 146 Score = 58.8 bits (136), Expect = 1e-08 Identities = 23/74 (31%), Positives = 37/74 (50%), Gaps = 1/74 (1%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLCGPGKCMNTADS-YK 403 CAP+ CL++G C++ + C C PG+ G C+ + C C G+C D ++ Sbjct: 1060 CAPSPCLHDGACRDLFD--AFACACGPGWEGPRCEAHVDPCHSAPCARGRCHTHPDGRFE 1117 Query: 404 CACPVTYTGKNCEV 445 C CP + G C + Sbjct: 1118 CRCPPGFGGPRCRL 1131 Score = 54.0 bits (124), Expect = 3e-07 Identities = 26/80 (32%), Positives = 43/80 (53%), Gaps = 2/80 (2%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLCG-PGKCMNTADSYK 403 CA CL+ G C + + + C+CAPG+GG C + C+ C G C + + ++ Sbjct: 150 CASAPCLHGGSCLDGVGS--FRCVCAPGYGGTRCQLDLDECQSQPCAHGGTCHDLVNGFR 207 Query: 404 CACPVT-YTGKNCEVKQLIE 460 C C T Y G +CE ++++E Sbjct: 208 CDCAGTGYEGTHCE-REVLE 226 Score = 48.8 bits (111), Expect = 1e-05 Identities = 25/69 (36%), Positives = 35/69 (50%), Gaps = 4/69 (5%) Frame = +2 Query: 284 GYVCLCAPGFGGNNCDRIGESC--RPGLCGPGKCMNTADSYKCACPVTYTGKNCE--VKQ 451 G++C C PGF G +C + C RP L G G C + + ++C CP Y G CE V + Sbjct: 303 GFLCHCPPGFEGADCGVEVDECASRPCLNG-GHCQDLPNGFQCHCPDGYAGPTCEEDVDE 361 Query: 452 LIEYPAFTG 478 + P G Sbjct: 362 CLSDPCLHG 370 Score = 46.4 bits (105), Expect = 6e-05 Identities = 23/77 (29%), Positives = 37/77 (48%), Gaps = 2/77 (2%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCA-PGFGGNNCDRIGESCRPGLCGPG-KCMNTADSY 400 C C + G C + + +G+ C CA G+ G +C+R C C C+ S+ Sbjct: 188 CQSQPCAHGGTCHDLV--NGFRCDCAGTGYEGTHCEREVLECASAPCEHNASCLEGLGSF 245 Query: 401 KCACPVTYTGKNCEVKQ 451 +C C Y+G+ CEV + Sbjct: 246 RCLCWPGYSGELCEVDE 262 Score = 39.9 bits (89), Expect = 0.006 Identities = 22/76 (28%), Positives = 32/76 (42%), Gaps = 5/76 (6%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLCG-PGKCM----NTA 391 C + CL+ G C + + GY+C C +GG +C C+ C C+ + Sbjct: 362 CLSDPCLHGGTCSDTVA--GYICRCPETWGGRDCSVQLTGCQGHTCPLAATCIPIFESGV 419 Query: 392 DSYKCACPVTYTGKNC 439 SY C CP G C Sbjct: 420 HSYVCHCPPGTHGPFC 435 Score = 38.3 bits (85), Expect = 0.017 Identities = 19/57 (33%), Positives = 27/57 (47%), Gaps = 1/57 (1%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLC-GPGKCMNTAD 394 CA C +N C E L + CLC PG+ G C+ + C C G+C+ +D Sbjct: 227 CASAPCEHNASCLEGLGS--FRCLCWPGYSGELCEVDEDECASSPCQHGGRCLQRSD 281 Score = 37.9 bits (84), Expect = 0.022 Identities = 20/70 (28%), Positives = 29/70 (41%), Gaps = 4/70 (5%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDR----IGESCRPGLCGPGKCMNTAD 394 C+P+ C N G C +T + + C C F G C + G+ C P P C D Sbjct: 811 CSPDPCFNGGTC--LVTWNDFHCTCPANFTGPTCAQQLWCPGQPCLP----PATCEEVPD 864 Query: 395 SYKCACPVTY 424 + C T+ Sbjct: 865 GFVCVAEATF 874 Score = 35.9 bits (79), Expect = 0.090 Identities = 21/82 (25%), Positives = 31/82 (37%), Gaps = 2/82 (2%) Frame = +2 Query: 227 CAPNL-CLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLC-GPGKCMNTADSY 400 C+ N+ CL+ C+ C C G G C C C G C Sbjct: 1138 CSLNVTCLDGSPCEGGSPAAN--CSCLEGLAGQRCQVPTLPCEANPCLNGGTCRAAGGVS 1195 Query: 401 KCACPVTYTGKNCEVKQLIEYP 466 +C C ++G+ CEV + + P Sbjct: 1196 ECICNARFSGQFCEVAKGLPLP 1217 Score = 33.5 bits (73), Expect = 0.48 Identities = 12/34 (35%), Positives = 17/34 (50%), Gaps = 1/34 (2%) Frame = +2 Query: 341 ESCRPGLC-GPGKCMNTADSYKCACPVTYTGKNC 439 + C P C G C+ T + + C CP +TG C Sbjct: 809 DMCSPDPCFNGGTCLVTWNDFHCTCPANFTGPTC 842 >AL445489-3|CAM14433.1| 1176|Homo sapiens crumbs homolog 2 (Drosophila) protein. Length = 1176 Score = 60.5 bits (140), Expect = 4e-09 Identities = 27/75 (36%), Positives = 38/75 (50%), Gaps = 1/75 (1%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLC-GPGKCMNTADSYK 403 CA CLN G CQ+ +G+ C C G+ G C+ + C C G C +T Y Sbjct: 324 CASRPCLNGGHCQDL--PNGFQCHCPDGYAGPTCEEDVDECLSDPCLHGGTCSDTVAGYI 381 Query: 404 CACPVTYTGKNCEVK 448 C CP T+ G++C V+ Sbjct: 382 CRCPETWGGRDCSVQ 396 Score = 59.3 bits (137), Expect = 8e-09 Identities = 27/76 (35%), Positives = 37/76 (48%), Gaps = 2/76 (2%) Frame = +2 Query: 227 CAPNLCLNNGVC-QEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLCGPGK-CMNTADSY 400 CA C + +C + G+ C C PGF G C+ + C C G C N AD Y Sbjct: 71 CATQPCHHGALCVPQGPDPTGFRCYCVPGFQGPRCELDIDECASRPCHHGATCRNLADRY 130 Query: 401 KCACPVTYTGKNCEVK 448 +C CP+ Y G CE++ Sbjct: 131 ECHCPLGYAGVTCEME 146 Score = 58.4 bits (135), Expect = 1e-08 Identities = 23/72 (31%), Positives = 36/72 (50%), Gaps = 1/72 (1%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLCGPGKCMNTADS-YK 403 CAP+ CL++G C++ + C C PG+ G C+ + C C G+C D ++ Sbjct: 1060 CAPSPCLHDGACRDLFD--AFACACGPGWEGPRCEAHVDPCHSAPCARGRCHTHPDGRFE 1117 Query: 404 CACPVTYTGKNC 439 C CP + G C Sbjct: 1118 CRCPPGFGGPRC 1129 Score = 54.0 bits (124), Expect = 3e-07 Identities = 26/80 (32%), Positives = 43/80 (53%), Gaps = 2/80 (2%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLCG-PGKCMNTADSYK 403 CA CL+ G C + + + C+CAPG+GG C + C+ C G C + + ++ Sbjct: 150 CASAPCLHGGSCLDGVGS--FRCVCAPGYGGTRCQLDLDECQSQPCAHGGTCHDLVNGFR 207 Query: 404 CACPVT-YTGKNCEVKQLIE 460 C C T Y G +CE ++++E Sbjct: 208 CDCAGTGYEGTHCE-REVLE 226 Score = 48.8 bits (111), Expect = 1e-05 Identities = 25/69 (36%), Positives = 35/69 (50%), Gaps = 4/69 (5%) Frame = +2 Query: 284 GYVCLCAPGFGGNNCDRIGESC--RPGLCGPGKCMNTADSYKCACPVTYTGKNCE--VKQ 451 G++C C PGF G +C + C RP L G G C + + ++C CP Y G CE V + Sbjct: 303 GFLCHCPPGFEGADCGVEVDECASRPCLNG-GHCQDLPNGFQCHCPDGYAGPTCEEDVDE 361 Query: 452 LIEYPAFTG 478 + P G Sbjct: 362 CLSDPCLHG 370 Score = 46.4 bits (105), Expect = 6e-05 Identities = 23/77 (29%), Positives = 37/77 (48%), Gaps = 2/77 (2%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCA-PGFGGNNCDRIGESCRPGLCGPG-KCMNTADSY 400 C C + G C + + +G+ C CA G+ G +C+R C C C+ S+ Sbjct: 188 CQSQPCAHGGTCHDLV--NGFRCDCAGTGYEGTHCEREVLECASAPCEHNASCLEGLGSF 245 Query: 401 KCACPVTYTGKNCEVKQ 451 +C C Y+G+ CEV + Sbjct: 246 RCLCWPGYSGELCEVDE 262 Score = 39.9 bits (89), Expect = 0.006 Identities = 22/76 (28%), Positives = 32/76 (42%), Gaps = 5/76 (6%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLCG-PGKCM----NTA 391 C + CL+ G C + + GY+C C +GG +C C+ C C+ + Sbjct: 362 CLSDPCLHGGTCSDTVA--GYICRCPETWGGRDCSVQLTGCQGHTCPLAATCIPIFESGV 419 Query: 392 DSYKCACPVTYTGKNC 439 SY C CP G C Sbjct: 420 HSYVCHCPPGTHGPFC 435 Score = 38.3 bits (85), Expect = 0.017 Identities = 19/57 (33%), Positives = 27/57 (47%), Gaps = 1/57 (1%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLC-GPGKCMNTAD 394 CA C +N C E L + CLC PG+ G C+ + C C G+C+ +D Sbjct: 227 CASAPCEHNASCLEGLGS--FRCLCWPGYSGELCEVDEDECASSPCQHGGRCLQRSD 281 Score = 37.9 bits (84), Expect = 0.022 Identities = 20/70 (28%), Positives = 29/70 (41%), Gaps = 4/70 (5%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDR----IGESCRPGLCGPGKCMNTAD 394 C+P+ C N G C +T + + C C F G C + G+ C P P C D Sbjct: 811 CSPDPCFNGGTC--LVTWNDFHCTCPANFTGPTCAQQLWCPGQPCLP----PATCEEVPD 864 Query: 395 SYKCACPVTY 424 + C T+ Sbjct: 865 GFVCVAEATF 874 Score = 33.5 bits (73), Expect = 0.48 Identities = 12/34 (35%), Positives = 17/34 (50%), Gaps = 1/34 (2%) Frame = +2 Query: 341 ESCRPGLC-GPGKCMNTADSYKCACPVTYTGKNC 439 + C P C G C+ T + + C CP +TG C Sbjct: 809 DMCSPDPCFNGGTCLVTWNDFHCTCPANFTGPTC 842 Score = 29.5 bits (63), Expect = 7.8 Identities = 12/33 (36%), Positives = 16/33 (48%), Gaps = 1/33 (3%) Frame = +2 Query: 347 CRPGLC-GPGKCMNTADSYKCACPVTYTGKNCE 442 C P C G C + D++ CAC + G CE Sbjct: 1060 CAPSPCLHDGACRDLFDAFACACGPGWEGPRCE 1092 >AL365504-3|CAI41011.1| 1285|Homo sapiens crumbs homolog 2 (Drosophila) protein. Length = 1285 Score = 60.5 bits (140), Expect = 4e-09 Identities = 27/75 (36%), Positives = 38/75 (50%), Gaps = 1/75 (1%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLC-GPGKCMNTADSYK 403 CA CLN G CQ+ +G+ C C G+ G C+ + C C G C +T Y Sbjct: 324 CASRPCLNGGHCQDL--PNGFQCHCPDGYAGPTCEEDVDECLSDPCLHGGTCSDTVAGYI 381 Query: 404 CACPVTYTGKNCEVK 448 C CP T+ G++C V+ Sbjct: 382 CRCPETWGGRDCSVQ 396 Score = 59.3 bits (137), Expect = 8e-09 Identities = 27/76 (35%), Positives = 37/76 (48%), Gaps = 2/76 (2%) Frame = +2 Query: 227 CAPNLCLNNGVC-QEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLCGPGK-CMNTADSY 400 CA C + +C + G+ C C PGF G C+ + C C G C N AD Y Sbjct: 71 CATQPCHHGALCVPQGPDPTGFRCYCVPGFQGPRCELDIDECASRPCHHGATCRNLADRY 130 Query: 401 KCACPVTYTGKNCEVK 448 +C CP+ Y G CE++ Sbjct: 131 ECHCPLGYAGVTCEME 146 Score = 58.8 bits (136), Expect = 1e-08 Identities = 23/74 (31%), Positives = 37/74 (50%), Gaps = 1/74 (1%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLCGPGKCMNTADS-YK 403 CAP+ CL++G C++ + C C PG+ G C+ + C C G+C D ++ Sbjct: 1060 CAPSPCLHDGACRDLFD--AFACACGPGWEGPRCEAHVDPCHSAPCARGRCHTHPDGRFE 1117 Query: 404 CACPVTYTGKNCEV 445 C CP + G C + Sbjct: 1118 CRCPPGFGGPRCRL 1131 Score = 54.0 bits (124), Expect = 3e-07 Identities = 26/80 (32%), Positives = 43/80 (53%), Gaps = 2/80 (2%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLCG-PGKCMNTADSYK 403 CA CL+ G C + + + C+CAPG+GG C + C+ C G C + + ++ Sbjct: 150 CASAPCLHGGSCLDGVGS--FRCVCAPGYGGTRCQLDLDECQSQPCAHGGTCHDLVNGFR 207 Query: 404 CACPVT-YTGKNCEVKQLIE 460 C C T Y G +CE ++++E Sbjct: 208 CDCAGTGYEGTHCE-REVLE 226 Score = 48.8 bits (111), Expect = 1e-05 Identities = 25/69 (36%), Positives = 35/69 (50%), Gaps = 4/69 (5%) Frame = +2 Query: 284 GYVCLCAPGFGGNNCDRIGESC--RPGLCGPGKCMNTADSYKCACPVTYTGKNCE--VKQ 451 G++C C PGF G +C + C RP L G G C + + ++C CP Y G CE V + Sbjct: 303 GFLCHCPPGFEGADCGVEVDECASRPCLNG-GHCQDLPNGFQCHCPDGYAGPTCEEDVDE 361 Query: 452 LIEYPAFTG 478 + P G Sbjct: 362 CLSDPCLHG 370 Score = 46.4 bits (105), Expect = 6e-05 Identities = 23/77 (29%), Positives = 37/77 (48%), Gaps = 2/77 (2%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCA-PGFGGNNCDRIGESCRPGLCGPG-KCMNTADSY 400 C C + G C + + +G+ C CA G+ G +C+R C C C+ S+ Sbjct: 188 CQSQPCAHGGTCHDLV--NGFRCDCAGTGYEGTHCEREVLECASAPCEHNASCLEGLGSF 245 Query: 401 KCACPVTYTGKNCEVKQ 451 +C C Y+G+ CEV + Sbjct: 246 RCLCWPGYSGELCEVDE 262 Score = 39.9 bits (89), Expect = 0.006 Identities = 22/76 (28%), Positives = 32/76 (42%), Gaps = 5/76 (6%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLCG-PGKCM----NTA 391 C + CL+ G C + + GY+C C +GG +C C+ C C+ + Sbjct: 362 CLSDPCLHGGTCSDTVA--GYICRCPETWGGRDCSVQLTGCQGHTCPLAATCIPIFESGV 419 Query: 392 DSYKCACPVTYTGKNC 439 SY C CP G C Sbjct: 420 HSYVCHCPPGTHGPFC 435 Score = 38.3 bits (85), Expect = 0.017 Identities = 19/57 (33%), Positives = 27/57 (47%), Gaps = 1/57 (1%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLC-GPGKCMNTAD 394 CA C +N C E L + CLC PG+ G C+ + C C G+C+ +D Sbjct: 227 CASAPCEHNASCLEGLGS--FRCLCWPGYSGELCEVDEDECASSPCQHGGRCLQRSD 281 Score = 37.9 bits (84), Expect = 0.022 Identities = 20/70 (28%), Positives = 29/70 (41%), Gaps = 4/70 (5%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDR----IGESCRPGLCGPGKCMNTAD 394 C+P+ C N G C +T + + C C F G C + G+ C P P C D Sbjct: 811 CSPDPCFNGGTC--LVTWNDFHCTCPANFTGPTCAQQLWCPGQPCLP----PATCEEVPD 864 Query: 395 SYKCACPVTY 424 + C T+ Sbjct: 865 GFVCVAEATF 874 Score = 35.9 bits (79), Expect = 0.090 Identities = 21/82 (25%), Positives = 31/82 (37%), Gaps = 2/82 (2%) Frame = +2 Query: 227 CAPNL-CLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLC-GPGKCMNTADSY 400 C+ N+ CL+ C+ C C G G C C C G C Sbjct: 1138 CSLNVTCLDGSPCEGGSPAAN--CSCLEGLAGQRCQVPTLPCEANPCLNGGTCRAAGGVS 1195 Query: 401 KCACPVTYTGKNCEVKQLIEYP 466 +C C ++G+ CEV + + P Sbjct: 1196 ECICNARFSGQFCEVAKGLPLP 1217 Score = 33.5 bits (73), Expect = 0.48 Identities = 12/34 (35%), Positives = 17/34 (50%), Gaps = 1/34 (2%) Frame = +2 Query: 341 ESCRPGLC-GPGKCMNTADSYKCACPVTYTGKNC 439 + C P C G C+ T + + C CP +TG C Sbjct: 809 DMCSPDPCFNGGTCLVTWNDFHCTCPANFTGPTC 842 >AL365504-2|CAM21391.1| 1176|Homo sapiens crumbs homolog 2 (Drosophila) protein. Length = 1176 Score = 60.5 bits (140), Expect = 4e-09 Identities = 27/75 (36%), Positives = 38/75 (50%), Gaps = 1/75 (1%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLC-GPGKCMNTADSYK 403 CA CLN G CQ+ +G+ C C G+ G C+ + C C G C +T Y Sbjct: 324 CASRPCLNGGHCQDL--PNGFQCHCPDGYAGPTCEEDVDECLSDPCLHGGTCSDTVAGYI 381 Query: 404 CACPVTYTGKNCEVK 448 C CP T+ G++C V+ Sbjct: 382 CRCPETWGGRDCSVQ 396 Score = 59.3 bits (137), Expect = 8e-09 Identities = 27/76 (35%), Positives = 37/76 (48%), Gaps = 2/76 (2%) Frame = +2 Query: 227 CAPNLCLNNGVC-QEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLCGPGK-CMNTADSY 400 CA C + +C + G+ C C PGF G C+ + C C G C N AD Y Sbjct: 71 CATQPCHHGALCVPQGPDPTGFRCYCVPGFQGPRCELDIDECASRPCHHGATCRNLADRY 130 Query: 401 KCACPVTYTGKNCEVK 448 +C CP+ Y G CE++ Sbjct: 131 ECHCPLGYAGVTCEME 146 Score = 58.4 bits (135), Expect = 1e-08 Identities = 23/72 (31%), Positives = 36/72 (50%), Gaps = 1/72 (1%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLCGPGKCMNTADS-YK 403 CAP+ CL++G C++ + C C PG+ G C+ + C C G+C D ++ Sbjct: 1060 CAPSPCLHDGACRDLFD--AFACACGPGWEGPRCEAHVDPCHSAPCARGRCHTHPDGRFE 1117 Query: 404 CACPVTYTGKNC 439 C CP + G C Sbjct: 1118 CRCPPGFGGPRC 1129 Score = 54.0 bits (124), Expect = 3e-07 Identities = 26/80 (32%), Positives = 43/80 (53%), Gaps = 2/80 (2%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLCG-PGKCMNTADSYK 403 CA CL+ G C + + + C+CAPG+GG C + C+ C G C + + ++ Sbjct: 150 CASAPCLHGGSCLDGVGS--FRCVCAPGYGGTRCQLDLDECQSQPCAHGGTCHDLVNGFR 207 Query: 404 CACPVT-YTGKNCEVKQLIE 460 C C T Y G +CE ++++E Sbjct: 208 CDCAGTGYEGTHCE-REVLE 226 Score = 48.8 bits (111), Expect = 1e-05 Identities = 25/69 (36%), Positives = 35/69 (50%), Gaps = 4/69 (5%) Frame = +2 Query: 284 GYVCLCAPGFGGNNCDRIGESC--RPGLCGPGKCMNTADSYKCACPVTYTGKNCE--VKQ 451 G++C C PGF G +C + C RP L G G C + + ++C CP Y G CE V + Sbjct: 303 GFLCHCPPGFEGADCGVEVDECASRPCLNG-GHCQDLPNGFQCHCPDGYAGPTCEEDVDE 361 Query: 452 LIEYPAFTG 478 + P G Sbjct: 362 CLSDPCLHG 370 Score = 46.4 bits (105), Expect = 6e-05 Identities = 23/77 (29%), Positives = 37/77 (48%), Gaps = 2/77 (2%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCA-PGFGGNNCDRIGESCRPGLCGPG-KCMNTADSY 400 C C + G C + + +G+ C CA G+ G +C+R C C C+ S+ Sbjct: 188 CQSQPCAHGGTCHDLV--NGFRCDCAGTGYEGTHCEREVLECASAPCEHNASCLEGLGSF 245 Query: 401 KCACPVTYTGKNCEVKQ 451 +C C Y+G+ CEV + Sbjct: 246 RCLCWPGYSGELCEVDE 262 Score = 39.9 bits (89), Expect = 0.006 Identities = 22/76 (28%), Positives = 32/76 (42%), Gaps = 5/76 (6%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLCG-PGKCM----NTA 391 C + CL+ G C + + GY+C C +GG +C C+ C C+ + Sbjct: 362 CLSDPCLHGGTCSDTVA--GYICRCPETWGGRDCSVQLTGCQGHTCPLAATCIPIFESGV 419 Query: 392 DSYKCACPVTYTGKNC 439 SY C CP G C Sbjct: 420 HSYVCHCPPGTHGPFC 435 Score = 38.3 bits (85), Expect = 0.017 Identities = 19/57 (33%), Positives = 27/57 (47%), Gaps = 1/57 (1%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLC-GPGKCMNTAD 394 CA C +N C E L + CLC PG+ G C+ + C C G+C+ +D Sbjct: 227 CASAPCEHNASCLEGLGS--FRCLCWPGYSGELCEVDEDECASSPCQHGGRCLQRSD 281 Score = 37.9 bits (84), Expect = 0.022 Identities = 20/70 (28%), Positives = 29/70 (41%), Gaps = 4/70 (5%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDR----IGESCRPGLCGPGKCMNTAD 394 C+P+ C N G C +T + + C C F G C + G+ C P P C D Sbjct: 811 CSPDPCFNGGTC--LVTWNDFHCTCPANFTGPTCAQQLWCPGQPCLP----PATCEEVPD 864 Query: 395 SYKCACPVTY 424 + C T+ Sbjct: 865 GFVCVAEATF 874 Score = 33.5 bits (73), Expect = 0.48 Identities = 12/34 (35%), Positives = 17/34 (50%), Gaps = 1/34 (2%) Frame = +2 Query: 341 ESCRPGLC-GPGKCMNTADSYKCACPVTYTGKNC 439 + C P C G C+ T + + C CP +TG C Sbjct: 809 DMCSPDPCFNGGTCLVTWNDFHCTCPANFTGPTC 842 Score = 29.5 bits (63), Expect = 7.8 Identities = 12/33 (36%), Positives = 16/33 (48%), Gaps = 1/33 (3%) Frame = +2 Query: 347 CRPGLC-GPGKCMNTADSYKCACPVTYTGKNCE 442 C P C G C + D++ CAC + G CE Sbjct: 1060 CAPSPCLHDGACRDLFDAFACACGPGWEGPRCE 1092 >AK123000-1|BAC85516.1| 1176|Homo sapiens 3 (HIVEP3). protein. Length = 1176 Score = 60.5 bits (140), Expect = 4e-09 Identities = 27/75 (36%), Positives = 38/75 (50%), Gaps = 1/75 (1%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLC-GPGKCMNTADSYK 403 CA CLN G CQ+ +G+ C C G+ G C+ + C C G C +T Y Sbjct: 324 CASRPCLNGGHCQDL--PNGFQCHCPDGYAGPTCEEDVDECLSDPCLHGGTCSDTVAGYI 381 Query: 404 CACPVTYTGKNCEVK 448 C CP T+ G++C V+ Sbjct: 382 CRCPETWGGRDCSVQ 396 Score = 60.1 bits (139), Expect = 5e-09 Identities = 27/76 (35%), Positives = 37/76 (48%), Gaps = 2/76 (2%) Frame = +2 Query: 227 CAPNLCLNNGVC-QEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLCGPGK-CMNTADSY 400 CA C + +C + +G+ C C PGF G C+ + C C G C N AD Y Sbjct: 71 CATQPCHHGALCVPQGPDPNGFRCYCVPGFQGPRCELDIDECASRPCHHGATCRNLADRY 130 Query: 401 KCACPVTYTGKNCEVK 448 +C CP+ Y G CE + Sbjct: 131 ECHCPLGYAGVTCETE 146 Score = 58.4 bits (135), Expect = 1e-08 Identities = 23/72 (31%), Positives = 36/72 (50%), Gaps = 1/72 (1%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLCGPGKCMNTADS-YK 403 CAP+ CL++G C++ + C C PG+ G C+ + C C G+C D ++ Sbjct: 1060 CAPSPCLHDGACRDLFD--AFACACGPGWEGPRCEAHVDPCHSAPCARGRCHTHPDGRFE 1117 Query: 404 CACPVTYTGKNC 439 C CP + G C Sbjct: 1118 CRCPPGFGGPRC 1129 Score = 51.6 bits (118), Expect = 2e-06 Identities = 25/80 (31%), Positives = 42/80 (52%), Gaps = 2/80 (2%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLCG-PGKCMNTADSYK 403 CA CL+ C + + + C+CAPG+GG C + C+ C G C + + ++ Sbjct: 150 CASAPCLHGASCLDGVGS--FRCVCAPGYGGTRCQLDLDECQSQPCAHGGTCHDLVNGFR 207 Query: 404 CACPVT-YTGKNCEVKQLIE 460 C C T Y G +CE ++++E Sbjct: 208 CDCAGTGYEGTHCE-REVLE 226 Score = 48.8 bits (111), Expect = 1e-05 Identities = 25/69 (36%), Positives = 35/69 (50%), Gaps = 4/69 (5%) Frame = +2 Query: 284 GYVCLCAPGFGGNNCDRIGESC--RPGLCGPGKCMNTADSYKCACPVTYTGKNCE--VKQ 451 G++C C PGF G +C + C RP L G G C + + ++C CP Y G CE V + Sbjct: 303 GFLCHCPPGFEGADCGVEVDECASRPCLNG-GHCQDLPNGFQCHCPDGYAGPTCEEDVDE 361 Query: 452 LIEYPAFTG 478 + P G Sbjct: 362 CLSDPCLHG 370 Score = 46.4 bits (105), Expect = 6e-05 Identities = 23/77 (29%), Positives = 37/77 (48%), Gaps = 2/77 (2%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCA-PGFGGNNCDRIGESCRPGLCGPG-KCMNTADSY 400 C C + G C + + +G+ C CA G+ G +C+R C C C+ S+ Sbjct: 188 CQSQPCAHGGTCHDLV--NGFRCDCAGTGYEGTHCEREVLECASAPCEHNASCLEGLGSF 245 Query: 401 KCACPVTYTGKNCEVKQ 451 +C C Y+G+ CEV + Sbjct: 246 RCLCWPGYSGELCEVDE 262 Score = 39.9 bits (89), Expect = 0.006 Identities = 22/76 (28%), Positives = 32/76 (42%), Gaps = 5/76 (6%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLCG-PGKCM----NTA 391 C + CL+ G C + + GY+C C +GG +C C+ C C+ + Sbjct: 362 CLSDPCLHGGTCSDTVA--GYICRCPETWGGRDCSVQLTGCQGHTCPLAATCIPIFESGV 419 Query: 392 DSYKCACPVTYTGKNC 439 SY C CP G C Sbjct: 420 HSYVCHCPPGTHGPFC 435 Score = 38.3 bits (85), Expect = 0.017 Identities = 19/57 (33%), Positives = 27/57 (47%), Gaps = 1/57 (1%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLC-GPGKCMNTAD 394 CA C +N C E L + CLC PG+ G C+ + C C G+C+ +D Sbjct: 227 CASAPCEHNASCLEGLGS--FRCLCWPGYSGELCEVDEDECASSPCQHGGRCLQRSD 281 Score = 37.9 bits (84), Expect = 0.022 Identities = 20/70 (28%), Positives = 29/70 (41%), Gaps = 4/70 (5%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDR----IGESCRPGLCGPGKCMNTAD 394 C+P+ C N G C +T + + C C F G C + G+ C P P C D Sbjct: 811 CSPDPCFNGGTC--LVTWNDFHCTCPANFTGPTCAQQLWCPGQPCLP----PATCEEVPD 864 Query: 395 SYKCACPVTY 424 + C T+ Sbjct: 865 GFVCVAEATF 874 Score = 33.5 bits (73), Expect = 0.48 Identities = 12/34 (35%), Positives = 17/34 (50%), Gaps = 1/34 (2%) Frame = +2 Query: 341 ESCRPGLC-GPGKCMNTADSYKCACPVTYTGKNC 439 + C P C G C+ T + + C CP +TG C Sbjct: 809 DMCSPDPCFNGGTCLVTWNDFHCTCPANFTGPTC 842 Score = 29.5 bits (63), Expect = 7.8 Identities = 12/33 (36%), Positives = 16/33 (48%), Gaps = 1/33 (3%) Frame = +2 Query: 347 CRPGLC-GPGKCMNTADSYKCACPVTYTGKNCE 442 C P C G C + D++ CAC + G CE Sbjct: 1060 CAPSPCLHDGACRDLFDAFACACGPGWEGPRCE 1092 >AF442487-1|AAM21557.1| 737|Homo sapiens delta-notch-like EGF repeat-containing transmembrane protein protein. Length = 737 Score = 60.5 bits (140), Expect = 4e-09 Identities = 27/72 (37%), Positives = 35/72 (48%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLCGPGKCMNTADSYKC 406 CA + C NNG C + + C C+PGF G C ++ + C C G C + SYKC Sbjct: 434 CASSPCQNNGTCY--VDGVHFTCNCSPGFTGPTCAQLIDFCALSPCAHGTCRSVGTSYKC 491 Query: 407 ACPVTYTGKNCE 442 C Y G CE Sbjct: 492 LCDPGYHGLYCE 503 Score = 58.0 bits (134), Expect = 2e-08 Identities = 28/74 (37%), Positives = 37/74 (50%), Gaps = 1/74 (1%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLCGPG-KCMNTADSYK 403 CA CLN C ++ +G C+CAPGF G CD C C G C++ + Y Sbjct: 547 CANVSCLNGATC-DSDGLNG-TCICAPGFTGEECDIDINECDSNPCHHGGSCLDQPNGYN 604 Query: 404 CACPVTYTGKNCEV 445 C CP + G NCE+ Sbjct: 605 CHCPHGWVGANCEI 618 Score = 54.8 bits (126), Expect = 2e-07 Identities = 30/86 (34%), Positives = 36/86 (41%), Gaps = 14/86 (16%) Frame = +2 Query: 227 CAPNLCLNNGVCQ---EALTEH-------GYVCLCAPGFGGNNCDRIGESCRPGLCGPGK 376 CA C N GVC E +H GY C C G G NC + + C C G Sbjct: 48 CAAQPCRNGGVCTSRPEPDPQHPAPAGEPGYSCTCPAGISGANCQLVADPCASNPCHHGN 107 Query: 377 C----MNTADSYKCACPVTYTGKNCE 442 C +++D Y C C Y G NCE Sbjct: 108 CSSSSSSSSDGYLCICNEGYEGPNCE 133 Score = 49.2 bits (112), Expect = 9e-06 Identities = 24/74 (32%), Positives = 34/74 (45%), Gaps = 1/74 (1%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLC-GPGKCMNTADSYK 403 CA + C + G C+ T Y CLC PG+ G C+ C C C + + Y+ Sbjct: 472 CALSPCAH-GTCRSVGTS--YKCLCDPGYHGLYCEEEYNECLSAPCLNAATCRDLVNGYE 528 Query: 404 CACPVTYTGKNCEV 445 C C Y G +CE+ Sbjct: 529 CVCLAEYKGTHCEL 542 Score = 48.4 bits (110), Expect = 2e-05 Identities = 24/78 (30%), Positives = 34/78 (43%), Gaps = 4/78 (5%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEH---GYVCLCAPGFGGNNCDRIGESCRPGLCGPGK-CMNTAD 394 C C NN C +A + + C+C PG+ G C + C C G C+++ Sbjct: 353 CQRKPCQNNASCIDANEKQDGSNFTCVCLPGYTGELCQSKIDYCILDPCRNGATCISSLS 412 Query: 395 SYKCACPVTYTGKNCEVK 448 + C CP Y G CE K Sbjct: 413 GFTCQCPEGYFGSACEEK 430 Score = 43.6 bits (98), Expect = 4e-04 Identities = 20/74 (27%), Positives = 35/74 (47%), Gaps = 1/74 (1%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLCGPG-KCMNTADSYK 403 C CLN C++ + +GY C+C + G +C+ + C C G C + + Sbjct: 509 CLSAPCLNAATCRDLV--NGYECVCLAEYKGTHCELYKDPCANVSCLNGATCDSDGLNGT 566 Query: 404 CACPVTYTGKNCEV 445 C C +TG+ C++ Sbjct: 567 CICAPGFTGEECDI 580 Score = 33.5 bits (73), Expect = 0.48 Identities = 14/38 (36%), Positives = 23/38 (60%), Gaps = 2/38 (5%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEH--GYVCLCAPGFGGNNCDR 334 CA N C ++G C + + GY+C+C G+ G NC++ Sbjct: 98 CASNPC-HHGNCSSSSSSSSDGYLCICNEGYEGPNCEQ 134 Score = 32.7 bits (71), Expect = 0.84 Identities = 35/135 (25%), Positives = 51/135 (37%), Gaps = 23/135 (17%) Frame = +2 Query: 113 LAGASGFVGCISMLILGNEE----------KNIMALALEKENVQNCFTCAPNL------- 241 L + G V ML LGN K+I+AL L V TC P Sbjct: 261 LQASGGLVLLEEMLALGNNHFIGFVNDSVTKSIVALRLTL--VVKVSTCVPGESHANDLE 318 Query: 242 CLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLC-GPGKCMNT-----ADSYK 403 C G C +E + C C + G C+ ++C+ C C++ ++ Sbjct: 319 CSGKGKCTTKPSEATFSCTCEEQYVGTFCEEY-DACQRKPCQNNASCIDANEKQDGSNFT 377 Query: 404 CACPVTYTGKNCEVK 448 C C YTG+ C+ K Sbjct: 378 CVCLPGYTGELCQSK 392 >AF051345-1|AAC39880.2| 1624|Homo sapiens latent transforming growth factor-beta binding protein 4L protein. Length = 1624 Score = 60.5 bits (140), Expect = 4e-09 Identities = 29/79 (36%), Positives = 42/79 (53%), Gaps = 2/79 (2%) Frame = +2 Query: 203 ENVQNCFTCAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESC--RPGLCGPGK 376 ++V C T +P LC G C+ + C+C GF G+ C+ + C P CGPG+ Sbjct: 670 QDVDEC-TQSPGLC-GRGACKNL--PGSFRCVCPAGFRGSACEEDVDECAQEPPPCGPGR 725 Query: 377 CMNTADSYKCACPVTYTGK 433 C NTA S+ CACP + + Sbjct: 726 CDNTAGSFHCACPAGFRSR 744 Score = 53.6 bits (123), Expect = 4e-07 Identities = 30/89 (33%), Positives = 42/89 (47%), Gaps = 5/89 (5%) Frame = +2 Query: 191 ALEKENVQNCFTCAPNLCLNNGVCQEALTEHGYVCLCAPGFG----GNNCDRIGESCR-P 355 A E +V C P L G C+ T ++C+C G+ G +C + E + P Sbjct: 624 AAECLDVDECHRVPPPCDL--GRCEN--TPGSFLCVCPAGYQAAPHGASCQDVDECTQSP 679 Query: 356 GLCGPGKCMNTADSYKCACPVTYTGKNCE 442 GLCG G C N S++C CP + G CE Sbjct: 680 GLCGRGACKNLPGSFRCVCPAGFRGSACE 708 Score = 46.4 bits (105), Expect = 6e-05 Identities = 22/64 (34%), Positives = 31/64 (48%), Gaps = 4/64 (6%) Frame = +2 Query: 236 NLCLNNGVCQEALTEHGYVCLCAPGFG----GNNCDRIGESCRPGLCGPGKCMNTADSYK 403 + C +G C T+ + C CAPG+ G +C + E LC G C NT S++ Sbjct: 886 DFCFPHGECLN--TDGSFACTCAPGYRPGPRGASCLDVDECSEEDLCQSGICTNTDGSFE 943 Query: 404 CACP 415 C CP Sbjct: 944 CICP 947 Score = 41.9 bits (94), Expect = 0.001 Identities = 26/79 (32%), Positives = 36/79 (45%), Gaps = 6/79 (7%) Frame = +2 Query: 206 NVQNCFTCAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNN-----CDRIGESCRPGLCGP 370 +V C + AP C +G C TE + C CAPG+ + C + E C P Sbjct: 834 DVDECSSGAPP-CGPHGHCTN--TEGSFRCSCAPGYRAPSGRPGPCADVNECLEGDFCFP 890 Query: 371 -GKCMNTADSYKCACPVTY 424 G+C+NT S+ C C Y Sbjct: 891 HGECLNTDGSFACTCAPGY 909 Score = 41.1 bits (92), Expect = 0.002 Identities = 19/48 (39%), Positives = 24/48 (50%), Gaps = 5/48 (10%) Frame = +2 Query: 284 GYVCLCAPGFG----GNNCDRIGESCR-PGLCGPGKCMNTADSYKCAC 412 GY C C GF G C + E R P C PG+C N+ S++C C Sbjct: 567 GYTCACDSGFRLSPQGTRCIDVDECRRVPPPCAPGRCENSPGSFRCVC 614 Score = 39.9 bits (89), Expect = 0.006 Identities = 29/90 (32%), Positives = 38/90 (42%), Gaps = 9/90 (10%) Frame = +2 Query: 200 KENVQNCFTCAPNLCLNNGVCQEALTEHGYVCLCAPGFG----GNNCDRIGESCR-PGLC 364 +E+V C P C G C T + C C GF G C + E R P C Sbjct: 708 EEDVDECAQ-EPPPC-GPGRCDN--TAGSFHCACPAGFRSRGPGAPCQDVDECARSPPPC 763 Query: 365 GPGKCMNTADSYKCACPVTY----TGKNCE 442 G+C NT S++C CP+ + G CE Sbjct: 764 TYGRCENTEGSFQCVCPMGFQPNAAGSECE 793 Score = 37.9 bits (84), Expect = 0.022 Identities = 26/77 (33%), Positives = 39/77 (50%), Gaps = 6/77 (7%) Frame = +2 Query: 203 ENVQNCFTCAPNLCLNNGVCQEALTEHGYVCLCAPGF----GGNNCDRIGESCRPGLCGP 370 ++V C P C G C+ TE + C+C GF G+ C+ + E C L P Sbjct: 751 QDVDECARSPPP-C-TYGRCEN--TEGSFQCVCPMGFQPNAAGSECEDVDE-CENHLACP 805 Query: 371 GK-CMNTADSYKC-ACP 415 G+ C+N+ S++C ACP Sbjct: 806 GQECVNSPGSFQCRACP 822 Score = 37.9 bits (84), Expect = 0.022 Identities = 21/65 (32%), Positives = 31/65 (47%), Gaps = 10/65 (15%) Frame = +2 Query: 242 CLNNGVCQEAL---TEHGYVCLCAPGFGGN----NCDRIGESCR---PGLCGPGKCMNTA 391 C +CQ + T+ + C+C PG +C + E CR P LCG +C N+ Sbjct: 924 CSEEDLCQSGICTNTDGSFECICPPGHRAGPDLASCLDVDE-CRERGPALCGSQRCENSP 982 Query: 392 DSYKC 406 SY+C Sbjct: 983 GSYRC 987 Score = 37.5 bits (83), Expect = 0.029 Identities = 26/81 (32%), Positives = 37/81 (45%), Gaps = 8/81 (9%) Frame = +2 Query: 206 NVQNCFTCAPNLCLNNGVCQEALTEHGYVCLCAPGFGGN---NCDRIGESCR---PGLCG 367 +V C P LC + C+ + + V C PG+ CD + E C+ P +CG Sbjct: 961 DVDECRERGPALC-GSQRCENSPGSYRCVRDCDPGYHAGPEGTCDDVDE-CQEYGPEICG 1018 Query: 368 PGKCMNTADSYKC--ACPVTY 424 +C NT SY+C AC Y Sbjct: 1019 AQRCENTPGSYRCTPACDPGY 1039 Score = 36.7 bits (81), Expect = 0.052 Identities = 16/41 (39%), Positives = 19/41 (46%), Gaps = 2/41 (4%) Frame = +2 Query: 299 CAPGFGGNN--CDRIGESCRPGLCGPGKCMNTADSYKCACP 415 C GF N C+ + E G C G+C NT Y C CP Sbjct: 344 CPTGFERVNGSCEDVDECATGGRCQHGECANTRGGYTCVCP 384 Score = 36.7 bits (81), Expect = 0.052 Identities = 20/65 (30%), Positives = 28/65 (43%), Gaps = 5/65 (7%) Frame = +2 Query: 236 NLCLNNGVCQEALTEHGYVCLCAPGF----GGNNCDRIGE-SCRPGLCGPGKCMNTADSY 400 + C + VCQ + CLC G+ G +C + E G+CG C N S+ Sbjct: 1057 SFCGAHAVCQNL--PGSFQCLCDQGYEGARDGRHCVDVNECETLQGVCGAALCENVEGSF 1114 Query: 401 KCACP 415 C CP Sbjct: 1115 LCVCP 1119 Score = 35.9 bits (79), Expect = 0.090 Identities = 23/77 (29%), Positives = 34/77 (44%), Gaps = 6/77 (7%) Frame = +2 Query: 200 KENVQNCFTCAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRI----GESC--RPGL 361 + +V C +C +GVC T GY C C+ G+ + R+ + C Sbjct: 1251 RRDVDECQLFRDQVC-KSGVCVN--TAPGYSCYCSNGYYYHT-QRLECIDNDECADEEPA 1306 Query: 362 CGPGKCMNTADSYKCAC 412 C G+C+NT SY C C Sbjct: 1307 CEGGRCVNTVGSYHCTC 1323 Score = 34.3 bits (75), Expect = 0.27 Identities = 23/82 (28%), Positives = 31/82 (37%), Gaps = 6/82 (7%) Frame = +2 Query: 203 ENVQNCFTCAPNLCLNNGVCQEALTEHGYVCL--CAPGFG---GNNCDRIGESCRPGLCG 367 ++V C P +C G + T Y C C PG+ G C + E CG Sbjct: 1004 DDVDECQEYGPEIC---GAQRCENTPGSYRCTPACDPGYQPTPGGGCQDVDECRNRSFCG 1060 Query: 368 P-GKCMNTADSYKCACPVTYTG 430 C N S++C C Y G Sbjct: 1061 AHAVCQNLPGSFQCLCDQGYEG 1082 Score = 33.5 bits (73), Expect = 0.48 Identities = 10/20 (50%), Positives = 14/20 (70%) Frame = +2 Query: 353 PGLCGPGKCMNTADSYKCAC 412 P +CGPG+C++ Y CAC Sbjct: 553 PQVCGPGRCISRPSGYTCAC 572 Score = 31.9 bits (69), Expect = 1.5 Identities = 23/70 (32%), Positives = 30/70 (42%), Gaps = 9/70 (12%) Frame = +2 Query: 242 CLNNGVC--QEALTEHG-YVCLCAPG---FGGNNCDRIGESCRPGL--CGP-GKCMNTAD 394 C N+ C QE + G + C P C + E C G CGP G C NT Sbjct: 798 CENHLACPGQECVNSPGSFQCRACPSGHHLHRGRCTDVDE-CSSGAPPCGPHGHCTNTEG 856 Query: 395 SYKCACPVTY 424 S++C+C Y Sbjct: 857 SFRCSCAPGY 866 Score = 30.7 bits (66), Expect = 3.4 Identities = 13/31 (41%), Positives = 18/31 (58%) Frame = +2 Query: 320 NNCDRIGESCRPGLCGPGKCMNTADSYKCAC 412 N CD E+ P LC +C+NT S++C C Sbjct: 1576 NECDE-AEAASP-LCVNARCLNTDGSFRCIC 1604 Score = 29.5 bits (63), Expect = 7.8 Identities = 15/41 (36%), Positives = 17/41 (41%) Frame = +2 Query: 233 PNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRP 355 P +C N GVC + CLC P F G C RP Sbjct: 154 PLICHNGGVCVKPDR-----CLCPPDFAGKFCQLHSSGARP 189 >AF051344-1|AAC39879.2| 1557|Homo sapiens latent transforming growth factor-beta binding protein 4S protein. Length = 1557 Score = 60.5 bits (140), Expect = 4e-09 Identities = 29/79 (36%), Positives = 42/79 (53%), Gaps = 2/79 (2%) Frame = +2 Query: 203 ENVQNCFTCAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESC--RPGLCGPGK 376 ++V C T +P LC G C+ + C+C GF G+ C+ + C P CGPG+ Sbjct: 603 QDVDEC-TQSPGLC-GRGACKNL--PGSFRCVCPAGFRGSACEEDVDECAQEPPPCGPGR 658 Query: 377 CMNTADSYKCACPVTYTGK 433 C NTA S+ CACP + + Sbjct: 659 CDNTAGSFHCACPAGFRSR 677 Score = 53.6 bits (123), Expect = 4e-07 Identities = 30/89 (33%), Positives = 42/89 (47%), Gaps = 5/89 (5%) Frame = +2 Query: 191 ALEKENVQNCFTCAPNLCLNNGVCQEALTEHGYVCLCAPGFG----GNNCDRIGESCR-P 355 A E +V C P L G C+ T ++C+C G+ G +C + E + P Sbjct: 557 AAECLDVDECHRVPPPCDL--GRCEN--TPGSFLCVCPAGYQAAPHGASCQDVDECTQSP 612 Query: 356 GLCGPGKCMNTADSYKCACPVTYTGKNCE 442 GLCG G C N S++C CP + G CE Sbjct: 613 GLCGRGACKNLPGSFRCVCPAGFRGSACE 641 Score = 46.4 bits (105), Expect = 6e-05 Identities = 22/64 (34%), Positives = 31/64 (48%), Gaps = 4/64 (6%) Frame = +2 Query: 236 NLCLNNGVCQEALTEHGYVCLCAPGFG----GNNCDRIGESCRPGLCGPGKCMNTADSYK 403 + C +G C T+ + C CAPG+ G +C + E LC G C NT S++ Sbjct: 819 DFCFPHGECLN--TDGSFACTCAPGYRPGPRGASCLDVDECSEEDLCQSGICTNTDGSFE 876 Query: 404 CACP 415 C CP Sbjct: 877 CICP 880 Score = 41.9 bits (94), Expect = 0.001 Identities = 26/79 (32%), Positives = 36/79 (45%), Gaps = 6/79 (7%) Frame = +2 Query: 206 NVQNCFTCAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNN-----CDRIGESCRPGLCGP 370 +V C + AP C +G C TE + C CAPG+ + C + E C P Sbjct: 767 DVDECSSGAPP-CGPHGHCTN--TEGSFRCSCAPGYRAPSGRPGPCADVNECLEGDFCFP 823 Query: 371 -GKCMNTADSYKCACPVTY 424 G+C+NT S+ C C Y Sbjct: 824 HGECLNTDGSFACTCAPGY 842 Score = 41.1 bits (92), Expect = 0.002 Identities = 19/48 (39%), Positives = 24/48 (50%), Gaps = 5/48 (10%) Frame = +2 Query: 284 GYVCLCAPGFG----GNNCDRIGESCR-PGLCGPGKCMNTADSYKCAC 412 GY C C GF G C + E R P C PG+C N+ S++C C Sbjct: 500 GYTCACDSGFRLSPQGTRCIDVDECRRVPPPCAPGRCENSPGSFRCVC 547 Score = 39.9 bits (89), Expect = 0.006 Identities = 29/90 (32%), Positives = 38/90 (42%), Gaps = 9/90 (10%) Frame = +2 Query: 200 KENVQNCFTCAPNLCLNNGVCQEALTEHGYVCLCAPGFG----GNNCDRIGESCR-PGLC 364 +E+V C P C G C T + C C GF G C + E R P C Sbjct: 641 EEDVDECAQ-EPPPC-GPGRCDN--TAGSFHCACPAGFRSRGPGAPCQDVDECARSPPPC 696 Query: 365 GPGKCMNTADSYKCACPVTY----TGKNCE 442 G+C NT S++C CP+ + G CE Sbjct: 697 TYGRCENTEGSFQCVCPMGFQPNAAGSECE 726 Score = 37.9 bits (84), Expect = 0.022 Identities = 26/77 (33%), Positives = 39/77 (50%), Gaps = 6/77 (7%) Frame = +2 Query: 203 ENVQNCFTCAPNLCLNNGVCQEALTEHGYVCLCAPGF----GGNNCDRIGESCRPGLCGP 370 ++V C P C G C+ TE + C+C GF G+ C+ + E C L P Sbjct: 684 QDVDECARSPPP-C-TYGRCEN--TEGSFQCVCPMGFQPNAAGSECEDVDE-CENHLACP 738 Query: 371 GK-CMNTADSYKC-ACP 415 G+ C+N+ S++C ACP Sbjct: 739 GQECVNSPGSFQCRACP 755 Score = 37.9 bits (84), Expect = 0.022 Identities = 21/65 (32%), Positives = 31/65 (47%), Gaps = 10/65 (15%) Frame = +2 Query: 242 CLNNGVCQEAL---TEHGYVCLCAPGFGGN----NCDRIGESCR---PGLCGPGKCMNTA 391 C +CQ + T+ + C+C PG +C + E CR P LCG +C N+ Sbjct: 857 CSEEDLCQSGICTNTDGSFECICPPGHRAGPDLASCLDVDE-CRERGPALCGSQRCENSP 915 Query: 392 DSYKC 406 SY+C Sbjct: 916 GSYRC 920 Score = 37.5 bits (83), Expect = 0.029 Identities = 26/81 (32%), Positives = 37/81 (45%), Gaps = 8/81 (9%) Frame = +2 Query: 206 NVQNCFTCAPNLCLNNGVCQEALTEHGYVCLCAPGFGGN---NCDRIGESCR---PGLCG 367 +V C P LC + C+ + + V C PG+ CD + E C+ P +CG Sbjct: 894 DVDECRERGPALC-GSQRCENSPGSYRCVRDCDPGYHAGPEGTCDDVDE-CQEYGPEICG 951 Query: 368 PGKCMNTADSYKC--ACPVTY 424 +C NT SY+C AC Y Sbjct: 952 AQRCENTPGSYRCTPACDPGY 972 Score = 36.7 bits (81), Expect = 0.052 Identities = 16/41 (39%), Positives = 19/41 (46%), Gaps = 2/41 (4%) Frame = +2 Query: 299 CAPGFGGNN--CDRIGESCRPGLCGPGKCMNTADSYKCACP 415 C GF N C+ + E G C G+C NT Y C CP Sbjct: 277 CPTGFERVNGSCEDVDECATGGRCQHGECANTRGGYTCVCP 317 Score = 36.7 bits (81), Expect = 0.052 Identities = 20/65 (30%), Positives = 28/65 (43%), Gaps = 5/65 (7%) Frame = +2 Query: 236 NLCLNNGVCQEALTEHGYVCLCAPGF----GGNNCDRIGE-SCRPGLCGPGKCMNTADSY 400 + C + VCQ + CLC G+ G +C + E G+CG C N S+ Sbjct: 990 SFCGAHAVCQNL--PGSFQCLCDQGYEGARDGRHCVDVNECETLQGVCGAALCENVEGSF 1047 Query: 401 KCACP 415 C CP Sbjct: 1048 LCVCP 1052 Score = 35.9 bits (79), Expect = 0.090 Identities = 23/77 (29%), Positives = 34/77 (44%), Gaps = 6/77 (7%) Frame = +2 Query: 200 KENVQNCFTCAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRI----GESC--RPGL 361 + +V C +C +GVC T GY C C+ G+ + R+ + C Sbjct: 1184 RRDVDECQLFRDQVC-KSGVCVN--TAPGYSCYCSNGYYYHT-QRLECIDNDECADEEPA 1239 Query: 362 CGPGKCMNTADSYKCAC 412 C G+C+NT SY C C Sbjct: 1240 CEGGRCVNTVGSYHCTC 1256 Score = 34.3 bits (75), Expect = 0.27 Identities = 23/82 (28%), Positives = 31/82 (37%), Gaps = 6/82 (7%) Frame = +2 Query: 203 ENVQNCFTCAPNLCLNNGVCQEALTEHGYVCL--CAPGFG---GNNCDRIGESCRPGLCG 367 ++V C P +C G + T Y C C PG+ G C + E CG Sbjct: 937 DDVDECQEYGPEIC---GAQRCENTPGSYRCTPACDPGYQPTPGGGCQDVDECRNRSFCG 993 Query: 368 P-GKCMNTADSYKCACPVTYTG 430 C N S++C C Y G Sbjct: 994 AHAVCQNLPGSFQCLCDQGYEG 1015 Score = 33.5 bits (73), Expect = 0.48 Identities = 10/20 (50%), Positives = 14/20 (70%) Frame = +2 Query: 353 PGLCGPGKCMNTADSYKCAC 412 P +CGPG+C++ Y CAC Sbjct: 486 PQVCGPGRCISRPSGYTCAC 505 Score = 31.9 bits (69), Expect = 1.5 Identities = 23/70 (32%), Positives = 30/70 (42%), Gaps = 9/70 (12%) Frame = +2 Query: 242 CLNNGVC--QEALTEHG-YVCLCAPG---FGGNNCDRIGESCRPGL--CGP-GKCMNTAD 394 C N+ C QE + G + C P C + E C G CGP G C NT Sbjct: 731 CENHLACPGQECVNSPGSFQCRACPSGHHLHRGRCTDVDE-CSSGAPPCGPHGHCTNTEG 789 Query: 395 SYKCACPVTY 424 S++C+C Y Sbjct: 790 SFRCSCAPGY 799 Score = 30.7 bits (66), Expect = 3.4 Identities = 17/45 (37%), Positives = 19/45 (42%) Frame = +2 Query: 221 FTCAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRP 355 F C P +C N GVC + CLC P F G C RP Sbjct: 84 FLC-PLICHNGGVCVKPDR-----CLCPPDFAGKFCQLHSSGARP 122 Score = 30.7 bits (66), Expect = 3.4 Identities = 13/31 (41%), Positives = 18/31 (58%) Frame = +2 Query: 320 NNCDRIGESCRPGLCGPGKCMNTADSYKCAC 412 N CD E+ P LC +C+NT S++C C Sbjct: 1509 NECDE-AEAASP-LCVNARCLNTDGSFRCIC 1537 >AC008273-1|AAF19247.2| 291|Homo sapiens unknown protein. Length = 291 Score = 60.5 bits (140), Expect = 4e-09 Identities = 27/72 (37%), Positives = 35/72 (48%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLCGPGKCMNTADSYKC 406 CA + C NNG C + + C C+PGF G C ++ + C C G C + SYKC Sbjct: 151 CASSPCQNNGTCY--VDGVHFTCNCSPGFTGPTCAQLIDFCALSPCAHGTCRSVGTSYKC 208 Query: 407 ACPVTYTGKNCE 442 C Y G CE Sbjct: 209 LCDPGYHGLYCE 220 Score = 49.2 bits (112), Expect = 9e-06 Identities = 24/74 (32%), Positives = 34/74 (45%), Gaps = 1/74 (1%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLC-GPGKCMNTADSYK 403 CA + C + G C+ T Y CLC PG+ G C+ C C C + + Y+ Sbjct: 189 CALSPCAH-GTCRSVGTS--YKCLCDPGYHGLYCEEEYNECLSAPCLNAATCRDLVNGYE 245 Query: 404 CACPVTYTGKNCEV 445 C C Y G +CE+ Sbjct: 246 CVCLAEYKGTHCEL 259 Score = 48.4 bits (110), Expect = 2e-05 Identities = 24/78 (30%), Positives = 34/78 (43%), Gaps = 4/78 (5%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEH---GYVCLCAPGFGGNNCDRIGESCRPGLCGPGK-CMNTAD 394 C C NN C +A + + C+C PG+ G C + C C G C+++ Sbjct: 70 CQRKPCQNNASCIDANEKQDGSNFTCVCLPGYTGELCQSKIDYCILDPCRNGATCISSLS 129 Query: 395 SYKCACPVTYTGKNCEVK 448 + C CP Y G CE K Sbjct: 130 GFTCQCPEGYFGSACEEK 147 Score = 35.1 bits (77), Expect = 0.16 Identities = 18/68 (26%), Positives = 30/68 (44%), Gaps = 1/68 (1%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLCGPG-KCMNTADSYK 403 C CLN C++ + +GY C+C + G +C+ + C C G C + + Sbjct: 226 CLSAPCLNAATCRDLV--NGYECVCLAEYKGTHCELYKDPCANVSCLNGATCDSDGLNGT 283 Query: 404 CACPVTYT 427 C C +T Sbjct: 284 CICAPGFT 291 Score = 32.3 bits (70), Expect = 1.1 Identities = 18/75 (24%), Positives = 31/75 (41%), Gaps = 6/75 (8%) Frame = +2 Query: 242 CLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLC-GPGKCMNT-----ADSYK 403 C G C +E + C C + G C+ ++C+ C C++ ++ Sbjct: 36 CSGKGKCTTKPSEATFSCTCEEQYVGTFCEEY-DACQRKPCQNNASCIDANEKQDGSNFT 94 Query: 404 CACPVTYTGKNCEVK 448 C C YTG+ C+ K Sbjct: 95 CVCLPGYTGELCQSK 109 >BC000218-1|AAH00218.1| 618|Homo sapiens delta-like 3 (Drosophila) protein. Length = 618 Score = 60.1 bits (139), Expect = 5e-09 Identities = 26/75 (34%), Positives = 38/75 (50%), Gaps = 2/75 (2%) Frame = +2 Query: 224 TCAPNLCLNNGVCQE-ALTEHGYVCLCAPGFGGNNCDRIGESCRPGLC-GPGKCMNTADS 397 TCA C N G+C A + Y+C C PGF G+NC++ + C C G C++ + Sbjct: 315 TCADGPCFNGGLCVGGADPDSAYICHCPPGFQGSNCEKRVDRCSLQPCRNGGLCLDLGHA 374 Query: 398 YKCACPVTYTGKNCE 442 +C C + G CE Sbjct: 375 LRCRCRAGFAGPRCE 389 Score = 58.0 bits (134), Expect = 2e-08 Identities = 30/76 (39%), Positives = 36/76 (47%), Gaps = 4/76 (5%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLC-GPGKCMNTAD--- 394 C N C N G C E T + C C GF G C+ G +C G C G C+ AD Sbjct: 278 CDGNPCANGGSCSE--TPRSFECTCPRGFYGLRCEVSGVTCADGPCFNGGLCVGGADPDS 335 Query: 395 SYKCACPVTYTGKNCE 442 +Y C CP + G NCE Sbjct: 336 AYICHCPPGFQGSNCE 351 Score = 53.2 bits (122), Expect = 6e-07 Identities = 27/73 (36%), Positives = 30/73 (41%), Gaps = 1/73 (1%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLCG-PGKCMNTADSYK 403 CA C N G C E H C CA GFGG +C + C C G+C Sbjct: 395 CAGRACANGGTCVEGGGAHR--CSCALGFGGRDCRERADPCAARPCAHGGRCYAHFSGLV 452 Query: 404 CACPVTYTGKNCE 442 CAC Y G CE Sbjct: 453 CACAPGYMGARCE 465 Score = 48.0 bits (109), Expect = 2e-05 Identities = 20/72 (27%), Positives = 34/72 (47%), Gaps = 1/72 (1%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLC-GPGKCMNTADSYK 403 C+ C N G+C + H C C GF G C+ + C C G C+ +++ Sbjct: 357 CSLQPCRNGGLCLDL--GHALRCRCRAGFAGPRCEHDLDDCAGRACANGGTCVEGGGAHR 414 Query: 404 CACPVTYTGKNC 439 C+C + + G++C Sbjct: 415 CSCALGFGGRDC 426 Score = 33.9 bits (74), Expect = 0.36 Identities = 20/57 (35%), Positives = 25/57 (43%), Gaps = 2/57 (3%) Frame = +2 Query: 314 GGNNCDRIGESCRPGLCGPGKCMNTADSYKCACPVTYTGKNCEVKQL--IEYPAFTG 478 G CD G C G G C T S++C CP + G CEV + + P F G Sbjct: 274 GPGPCD--GNPCANG----GSCSETPRSFECTCPRGFYGLRCEVSGVTCADGPCFNG 324 >AF241373-1|AAF62542.1| 618|Homo sapiens DLL3 protein precursor protein. Length = 618 Score = 60.1 bits (139), Expect = 5e-09 Identities = 26/75 (34%), Positives = 38/75 (50%), Gaps = 2/75 (2%) Frame = +2 Query: 224 TCAPNLCLNNGVCQE-ALTEHGYVCLCAPGFGGNNCDRIGESCRPGLC-GPGKCMNTADS 397 TCA C N G+C A + Y+C C PGF G+NC++ + C C G C++ + Sbjct: 315 TCADGPCFNGGLCVGGADPDSAYICHCPPGFQGSNCEKRVDRCSLQPCRNGGLCLDLGHA 374 Query: 398 YKCACPVTYTGKNCE 442 +C C + G CE Sbjct: 375 LRCRCRAGFAGPRCE 389 Score = 58.0 bits (134), Expect = 2e-08 Identities = 30/76 (39%), Positives = 36/76 (47%), Gaps = 4/76 (5%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLC-GPGKCMNTAD--- 394 C N C N G C E T + C C GF G C+ G +C G C G C+ AD Sbjct: 278 CDGNPCANGGSCSE--TPRSFECTCPRGFYGLRCEVSGVTCADGPCFNGGLCVGGADPDS 335 Query: 395 SYKCACPVTYTGKNCE 442 +Y C CP + G NCE Sbjct: 336 AYICHCPPGFQGSNCE 351 Score = 53.2 bits (122), Expect = 6e-07 Identities = 27/73 (36%), Positives = 30/73 (41%), Gaps = 1/73 (1%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLCG-PGKCMNTADSYK 403 CA C N G C E H C CA GFGG +C + C C G+C Sbjct: 395 CAGRACANGGTCVEGGGAHR--CSCALGFGGRDCRERADPCAARPCAHGGRCYAHFSGLV 452 Query: 404 CACPVTYTGKNCE 442 CAC Y G CE Sbjct: 453 CACAPGYMGARCE 465 Score = 48.0 bits (109), Expect = 2e-05 Identities = 20/72 (27%), Positives = 34/72 (47%), Gaps = 1/72 (1%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLC-GPGKCMNTADSYK 403 C+ C N G+C + H C C GF G C+ + C C G C+ +++ Sbjct: 357 CSLQPCRNGGLCLDL--GHALRCRCRAGFAGPRCEHDLDDCAGRACANGGTCVEGGGAHR 414 Query: 404 CACPVTYTGKNC 439 C+C + + G++C Sbjct: 415 CSCALGFGGRDC 426 Score = 33.9 bits (74), Expect = 0.36 Identities = 20/57 (35%), Positives = 25/57 (43%), Gaps = 2/57 (3%) Frame = +2 Query: 314 GGNNCDRIGESCRPGLCGPGKCMNTADSYKCACPVTYTGKNCEVKQL--IEYPAFTG 478 G CD G C G G C T S++C CP + G CEV + + P F G Sbjct: 274 GPGPCD--GNPCANG----GSCSETPRSFECTCPRGFYGLRCEVSGVTCADGPCFNG 324 >D63395-1|BAA09708.1| 1095|Homo sapiens notch related protein protein. Length = 1095 Score = 59.7 bits (138), Expect = 6e-09 Identities = 30/90 (33%), Positives = 43/90 (47%), Gaps = 4/90 (4%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLC-GPGKCMNTADSYK 403 C C N C + GY+C CAPG+ G NC + ++C+ C G C + Sbjct: 26 CESRPCQNGATCMAQPS--GYLCQCAPGYDGQNCSKELDACQSQPCHNHGTCTPKPGGFH 83 Query: 404 CACPVTYTGKNCE--VKQLIEYPAF-TGSA 484 CACP + G CE V + ++ P TG+A Sbjct: 84 CACPPGFVGLRCEGDVDECLDQPCHPTGTA 113 Score = 49.2 bits (112), Expect = 9e-06 Identities = 28/86 (32%), Positives = 39/86 (45%), Gaps = 7/86 (8%) Frame = +2 Query: 212 QNCF----TCAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLCGP--- 370 QNC C C N+G C G+ C C PGF G C+ + C C P Sbjct: 55 QNCSKELDACQSQPCHNHGTCTPK--PGGFHCACPPGFVGLRCEGDVDECLDQPCHPTGT 112 Query: 371 GKCMNTADSYKCACPVTYTGKNCEVK 448 C + A+++ C C +TG+ CEV+ Sbjct: 113 AACHSLANAFYCQCLPGHTGQWCEVE 138 Score = 43.6 bits (98), Expect = 4e-04 Identities = 20/52 (38%), Positives = 22/52 (42%), Gaps = 1/52 (1%) Frame = +2 Query: 287 YVCLCAPGFGGNNCDRIGESCRPGLCGPG-KCMNTADSYKCACPVTYTGKNC 439 Y C C PGF G+ C C C G CM Y C C Y G+NC Sbjct: 6 YFCHCPPGFQGSLCQDHVNPCESRPCQNGATCMAQPSGYLCQCAPGYDGQNC 57 Score = 38.7 bits (86), Expect = 0.013 Identities = 24/78 (30%), Positives = 31/78 (39%), Gaps = 7/78 (8%) Frame = +2 Query: 227 CAPNLCLNNGVCQE-ALTEHGYVCLCAPGFGGNNCDRIGESC------RPGLCGPGKCMN 385 C C + G C+ A + G++C C GF G C SC GLC P Sbjct: 142 CHSQPCFHGGTCEATAGSPLGFICHCPKGFEGPTCSHRAPSCGFHHCHHGGLCLPSP--K 199 Query: 386 TADSYKCACPVTYTGKNC 439 +CAC Y G +C Sbjct: 200 PGFPPRCACLSGYGGPDC 217 Score = 33.9 bits (74), Expect = 0.36 Identities = 21/75 (28%), Positives = 27/75 (36%), Gaps = 4/75 (5%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLC-GPGKCMNTADS-- 397 C C G + + C C PG G C+ + C C G C TA S Sbjct: 102 CLDQPCHPTGTAACHSLANAFYCQCLPGHTGQWCEVEIDPCHSQPCFHGGTCEATAGSPL 161 Query: 398 -YKCACPVTYTGKNC 439 + C CP + G C Sbjct: 162 GFICHCPKGFEGPTC 176 Score = 33.1 bits (72), Expect = 0.63 Identities = 18/51 (35%), Positives = 21/51 (41%), Gaps = 2/51 (3%) Frame = +2 Query: 233 PNLCLNNGVCQEA--LTEHGYVCLCAPGFGGNNCDRIGESCRPGLCGPGKC 379 P+ CL NG C E L G+ C C G C + G G G G C Sbjct: 229 PSPCLYNGSCSETTGLGGPGFRCSCPHSSPGPRCQKPGAKGCEGRSGDGAC 279 Score = 31.9 bits (69), Expect = 1.5 Identities = 23/86 (26%), Positives = 38/86 (44%), Gaps = 13/86 (15%) Frame = +2 Query: 224 TCAPNLCLNNGVCQEALTEHGYV--CLCAPGFGGNNCDRIGESCRPGLCGP-------GK 376 +C + C + G+C + + G+ C C G+GG +C + G CGP G Sbjct: 182 SCGFHHCHHGGLCLPS-PKPGFPPRCACLSGYGGPDC--LTPPAPKG-CGPPSPCLYNGS 237 Query: 377 CMNTAD----SYKCACPVTYTGKNCE 442 C T ++C+CP + G C+ Sbjct: 238 CSETTGLGGPGFRCSCPHSSPGPRCQ 263 >AK075302-1|BAC11535.1| 587|Homo sapiens protein ( Homo sapiens cDNA FLJ90821 fis, clone Y79AA1001328, highly similar to Delta-like protein 3 precursor. ). Length = 587 Score = 59.7 bits (138), Expect = 6e-09 Identities = 26/75 (34%), Positives = 38/75 (50%), Gaps = 2/75 (2%) Frame = +2 Query: 224 TCAPNLCLNNGVCQE-ALTEHGYVCLCAPGFGGNNCDRIGESCRPGLC-GPGKCMNTADS 397 TCA C N G+C A + Y+C C PGF G+NC++ + C C G C++ + Sbjct: 315 TCANGPCFNGGLCVGGADPDSAYICHCPPGFQGSNCEKRVDRCSLQPCRNGGLCLDLGHA 374 Query: 398 YKCACPVTYTGKNCE 442 +C C + G CE Sbjct: 375 LRCRCRAGFAGPRCE 389 Score = 57.6 bits (133), Expect = 3e-08 Identities = 30/76 (39%), Positives = 36/76 (47%), Gaps = 4/76 (5%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLC-GPGKCMNTAD--- 394 C N C N G C E T + C C GF G C+ G +C G C G C+ AD Sbjct: 278 CDGNPCANGGSCSE--TPRSFECTCPRGFYGLRCEVSGVTCANGPCFNGGLCVGGADPDS 335 Query: 395 SYKCACPVTYTGKNCE 442 +Y C CP + G NCE Sbjct: 336 AYICHCPPGFQGSNCE 351 Score = 52.8 bits (121), Expect = 7e-07 Identities = 27/73 (36%), Positives = 30/73 (41%), Gaps = 1/73 (1%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLCG-PGKCMNTADSYK 403 CA C N G C E H C CA GFGG +C + C C G+C Sbjct: 395 CAGRACANGGTCVEGGGAHR--CSCALGFGGRDCRERADPCAVRPCAHGGRCYAHFSGLV 452 Query: 404 CACPVTYTGKNCE 442 CAC Y G CE Sbjct: 453 CACAPGYMGARCE 465 Score = 48.0 bits (109), Expect = 2e-05 Identities = 20/72 (27%), Positives = 34/72 (47%), Gaps = 1/72 (1%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLC-GPGKCMNTADSYK 403 C+ C N G+C + H C C GF G C+ + C C G C+ +++ Sbjct: 357 CSLQPCRNGGLCLDL--GHALRCRCRAGFAGPRCEHDLDDCAGRACANGGTCVEGGGAHR 414 Query: 404 CACPVTYTGKNC 439 C+C + + G++C Sbjct: 415 CSCALGFGGRDC 426 Score = 33.1 bits (72), Expect = 0.63 Identities = 20/57 (35%), Positives = 24/57 (42%), Gaps = 2/57 (3%) Frame = +2 Query: 314 GGNNCDRIGESCRPGLCGPGKCMNTADSYKCACPVTYTGKNCEVKQL--IEYPAFTG 478 G CD G C G G C T S++C CP + G CEV + P F G Sbjct: 274 GPGPCD--GNPCANG----GSCSETPRSFECTCPRGFYGLRCEVSGVTCANGPCFNG 324 >Y13622-1|CAA73944.1| 1587|Homo sapiens latent TGF-beta binding protein-4 protein. Length = 1587 Score = 59.3 bits (137), Expect = 8e-09 Identities = 29/79 (36%), Positives = 42/79 (53%), Gaps = 2/79 (2%) Frame = +2 Query: 203 ENVQNCFTCAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESC--RPGLCGPGK 376 ++V C T +P LC G C+ + C+C GF G+ C+ + C P CGPG+ Sbjct: 633 QDVDEC-TQSPGLC-GRGGCKNL--PGSFRCVCPAGFRGSACEEDVDECAQEPPPCGPGR 688 Query: 377 CMNTADSYKCACPVTYTGK 433 C NTA S+ CACP + + Sbjct: 689 CDNTAGSFHCACPAGFRSR 707 Score = 53.2 bits (122), Expect = 6e-07 Identities = 30/89 (33%), Positives = 42/89 (47%), Gaps = 5/89 (5%) Frame = +2 Query: 191 ALEKENVQNCFTCAPNLCLNNGVCQEALTEHGYVCLCAPGFG----GNNCDRIGESCR-P 355 A E +V C P L G C+ T ++C+C G+ G +C + E + P Sbjct: 587 AAECLDVDECHRVPPPCDL--GRCEN--TPGSFLCVCPAGYQAAPHGASCQDVDECTQSP 642 Query: 356 GLCGPGKCMNTADSYKCACPVTYTGKNCE 442 GLCG G C N S++C CP + G CE Sbjct: 643 GLCGRGGCKNLPGSFRCVCPAGFRGSACE 671 Score = 46.4 bits (105), Expect = 6e-05 Identities = 22/64 (34%), Positives = 31/64 (48%), Gaps = 4/64 (6%) Frame = +2 Query: 236 NLCLNNGVCQEALTEHGYVCLCAPGFG----GNNCDRIGESCRPGLCGPGKCMNTADSYK 403 + C +G C T+ + C CAPG+ G +C + E LC G C NT S++ Sbjct: 849 DFCFPHGECLN--TDGSFACTCAPGYRPGPRGASCLDVDECSEEDLCQSGICTNTDGSFE 906 Query: 404 CACP 415 C CP Sbjct: 907 CICP 910 Score = 41.9 bits (94), Expect = 0.001 Identities = 26/79 (32%), Positives = 36/79 (45%), Gaps = 6/79 (7%) Frame = +2 Query: 206 NVQNCFTCAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNN-----CDRIGESCRPGLCGP 370 +V C + AP C +G C TE + C CAPG+ + C + E C P Sbjct: 797 DVDECSSGAPP-CGPHGHCTN--TEGSFRCSCAPGYRAPSGRPGPCADVNECLEGDFCFP 853 Query: 371 -GKCMNTADSYKCACPVTY 424 G+C+NT S+ C C Y Sbjct: 854 HGECLNTDGSFACTCAPGY 872 Score = 41.1 bits (92), Expect = 0.002 Identities = 19/48 (39%), Positives = 24/48 (50%), Gaps = 5/48 (10%) Frame = +2 Query: 284 GYVCLCAPGFG----GNNCDRIGESCR-PGLCGPGKCMNTADSYKCAC 412 GY C C GF G C + E R P C PG+C N+ S++C C Sbjct: 530 GYTCACDSGFRLSPQGTRCIDVDECRRVPPPCAPGRCENSPGSFRCVC 577 Score = 39.9 bits (89), Expect = 0.006 Identities = 29/90 (32%), Positives = 38/90 (42%), Gaps = 9/90 (10%) Frame = +2 Query: 200 KENVQNCFTCAPNLCLNNGVCQEALTEHGYVCLCAPGFG----GNNCDRIGESCR-PGLC 364 +E+V C P C G C T + C C GF G C + E R P C Sbjct: 671 EEDVDECAQ-EPPPC-GPGRCDN--TAGSFHCACPAGFRSRGPGAPCQDVDECARSPPPC 726 Query: 365 GPGKCMNTADSYKCACPVTY----TGKNCE 442 G+C NT S++C CP+ + G CE Sbjct: 727 TYGRCENTEGSFQCVCPMGFQPNTAGSECE 756 Score = 37.9 bits (84), Expect = 0.022 Identities = 21/65 (32%), Positives = 31/65 (47%), Gaps = 10/65 (15%) Frame = +2 Query: 242 CLNNGVCQEAL---TEHGYVCLCAPGFGGN----NCDRIGESCR---PGLCGPGKCMNTA 391 C +CQ + T+ + C+C PG +C + E CR P LCG +C N+ Sbjct: 887 CSEEDLCQSGICTNTDGSFECICPPGHRAGPDLASCLDVDE-CRERGPALCGSQRCENSP 945 Query: 392 DSYKC 406 SY+C Sbjct: 946 GSYRC 950 Score = 37.5 bits (83), Expect = 0.029 Identities = 26/81 (32%), Positives = 37/81 (45%), Gaps = 8/81 (9%) Frame = +2 Query: 206 NVQNCFTCAPNLCLNNGVCQEALTEHGYVCLCAPGFGGN---NCDRIGESCR---PGLCG 367 +V C P LC + C+ + + V C PG+ CD + E C+ P +CG Sbjct: 924 DVDECRERGPALC-GSQRCENSPGSYRCVRDCDPGYHAGPEGTCDDVDE-CQEYGPEICG 981 Query: 368 PGKCMNTADSYKC--ACPVTY 424 +C NT SY+C AC Y Sbjct: 982 AQRCENTPGSYRCTPACDPGY 1002 Score = 36.7 bits (81), Expect = 0.052 Identities = 16/41 (39%), Positives = 19/41 (46%), Gaps = 2/41 (4%) Frame = +2 Query: 299 CAPGFGGNN--CDRIGESCRPGLCGPGKCMNTADSYKCACP 415 C GF N C+ + E G C G+C NT Y C CP Sbjct: 307 CPTGFERVNGSCEDVDECATGGRCQHGECANTRGGYTCVCP 347 Score = 36.7 bits (81), Expect = 0.052 Identities = 20/65 (30%), Positives = 28/65 (43%), Gaps = 5/65 (7%) Frame = +2 Query: 236 NLCLNNGVCQEALTEHGYVCLCAPGF----GGNNCDRIGE-SCRPGLCGPGKCMNTADSY 400 + C + VCQ + CLC G+ G +C + E G+CG C N S+ Sbjct: 1020 SFCGAHAVCQNL--PGSFQCLCDQGYEGARDGRHCVDVNECETLQGVCGAALCENVEGSF 1077 Query: 401 KCACP 415 C CP Sbjct: 1078 LCVCP 1082 Score = 36.3 bits (80), Expect = 0.068 Identities = 25/77 (32%), Positives = 38/77 (49%), Gaps = 6/77 (7%) Frame = +2 Query: 203 ENVQNCFTCAPNLCLNNGVCQEALTEHGYVCLCAPGF----GGNNCDRIGESCRPGLCGP 370 ++V C P C G C+ TE + C+C GF G+ C+ + E C L P Sbjct: 714 QDVDECARSPPP-C-TYGRCEN--TEGSFQCVCPMGFQPNTAGSECEDVDE-CENHLACP 768 Query: 371 GK-CMNTADSYKC-ACP 415 G+ C+N+ S++C CP Sbjct: 769 GQECVNSPGSFQCRTCP 785 Score = 35.9 bits (79), Expect = 0.090 Identities = 23/77 (29%), Positives = 34/77 (44%), Gaps = 6/77 (7%) Frame = +2 Query: 200 KENVQNCFTCAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRI----GESC--RPGL 361 + +V C +C +GVC T GY C C+ G+ + R+ + C Sbjct: 1214 RRDVDECQLFRDQVC-KSGVCVN--TAPGYSCYCSNGYYYHT-QRLECIDNDECADEEPA 1269 Query: 362 CGPGKCMNTADSYKCAC 412 C G+C+NT SY C C Sbjct: 1270 CEGGRCVNTVGSYHCTC 1286 Score = 34.3 bits (75), Expect = 0.27 Identities = 23/82 (28%), Positives = 31/82 (37%), Gaps = 6/82 (7%) Frame = +2 Query: 203 ENVQNCFTCAPNLCLNNGVCQEALTEHGYVCL--CAPGFG---GNNCDRIGESCRPGLCG 367 ++V C P +C G + T Y C C PG+ G C + E CG Sbjct: 967 DDVDECQEYGPEIC---GAQRCENTPGSYRCTPACDPGYQPTPGGGCQDVDECRNRSFCG 1023 Query: 368 P-GKCMNTADSYKCACPVTYTG 430 C N S++C C Y G Sbjct: 1024 AHAVCQNLPGSFQCLCDQGYEG 1045 Score = 33.5 bits (73), Expect = 0.48 Identities = 10/20 (50%), Positives = 14/20 (70%) Frame = +2 Query: 353 PGLCGPGKCMNTADSYKCAC 412 P +CGPG+C++ Y CAC Sbjct: 516 PQVCGPGRCISRPSGYTCAC 535 Score = 31.5 bits (68), Expect = 1.9 Identities = 23/70 (32%), Positives = 30/70 (42%), Gaps = 9/70 (12%) Frame = +2 Query: 242 CLNNGVC--QEALTEHG-YVCLCAPG---FGGNNCDRIGESCRPGL--CGP-GKCMNTAD 394 C N+ C QE + G + C P C + E C G CGP G C NT Sbjct: 761 CENHLACPGQECVNSPGSFQCRTCPSGHHLHRGRCTDVDE-CSSGAPPCGPHGHCTNTEG 819 Query: 395 SYKCACPVTY 424 S++C+C Y Sbjct: 820 SFRCSCAPGY 829 Score = 30.7 bits (66), Expect = 3.4 Identities = 13/31 (41%), Positives = 18/31 (58%) Frame = +2 Query: 320 NNCDRIGESCRPGLCGPGKCMNTADSYKCAC 412 N CD E+ P LC +C+NT S++C C Sbjct: 1539 NECDE-AEAASP-LCVNARCLNTDGSFRCIC 1567 >BX640729-1|CAE45845.1| 674|Homo sapiens hypothetical protein protein. Length = 674 Score = 58.8 bits (136), Expect = 1e-08 Identities = 26/73 (35%), Positives = 36/73 (49%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLCGPGKCMNTADSYKC 406 C N CL+ G C++ + Y C C G+ G +C+ + C C G C + +Y C Sbjct: 524 CNSNPCLHGGNCEDIYSS--YHCSCPLGWSGKHCELNIDECFSNPCIHGNCSDRVAAYHC 581 Query: 407 ACPVTYTGKNCEV 445 C YTG NCEV Sbjct: 582 TCEPGYTGVNCEV 594 Score = 53.6 bits (123), Expect = 4e-07 Identities = 27/84 (32%), Positives = 43/84 (51%), Gaps = 1/84 (1%) Frame = +2 Query: 206 NVQNCFTCAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLCGPG-KCM 382 N+ CF+ N C++ G C + + Y C C PG+ G NC+ ++C+ C G C+ Sbjct: 558 NIDECFS---NPCIH-GNCSDRVA--AYHCTCEPGYTGVNCEVDIDNCQSHQCANGATCI 611 Query: 383 NTADSYKCACPVTYTGKNCEVKQL 454 + + Y C C +TGK C +L Sbjct: 612 SHTNGYSCLCFGNFTGKFCRQSRL 635 Score = 42.3 bits (95), Expect = 0.001 Identities = 38/151 (25%), Positives = 61/151 (40%), Gaps = 12/151 (7%) Frame = +2 Query: 29 SPDQWTVLELNQPLYIGGVPDFDQLPIDLAGASGFVGCISMLILGNEE-------KNIMA 187 S W + E +YIGG+PD + ++ F GCI + L N+ N + Sbjct: 199 SASTWKI-EKGDVIYIGGLPDKQETELN---GRFFKGCIQDVRLNNQNLEFFPNPTNNAS 254 Query: 188 LALEKENV-QNCF---TCAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRP 355 L NV Q C +C N C N GVC + + C C G C+ + + C Sbjct: 255 LNPVLVNVTQGCAGDNSCKSNPCHNGGVCHSRWDD--FSCSCPALTSGKACEEV-QWCGF 311 Query: 356 GLCGPG-KCMNTADSYKCACPVTYTGKNCEV 445 C G +C ++C + G++ ++ Sbjct: 312 SPCPHGAQCQPVLQGFECIANAVFNGQSGQI 342 Score = 33.1 bits (72), Expect = 0.63 Identities = 14/37 (37%), Positives = 19/37 (51%), Gaps = 1/37 (2%) Frame = +2 Query: 344 SCRPGLC-GPGKCMNTADSYKCACPVTYTGKNCEVKQ 451 SC+ C G C + D + C+CP +GK CE Q Sbjct: 271 SCKSNPCHNGGVCHSRWDDFSCSCPALTSGKACEEVQ 307 Score = 29.9 bits (64), Expect = 5.9 Identities = 11/23 (47%), Positives = 14/23 (60%) Frame = +2 Query: 371 GKCMNTADSYKCACPVTYTGKNC 439 G+C+N SY+C C Y G NC Sbjct: 66 GRCINLWLSYQCDCHRPYEGPNC 88 >AL136322-1|CAI16644.1| 674|Homo sapiens crumbs homolog 1 (Drosophila) protein. Length = 674 Score = 58.8 bits (136), Expect = 1e-08 Identities = 26/73 (35%), Positives = 36/73 (49%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLCGPGKCMNTADSYKC 406 C N CL+ G C++ + Y C C G+ G +C+ + C C G C + +Y C Sbjct: 524 CNSNPCLHGGNCEDIYSS--YHCSCPLGWSGKHCELNIDECFSNPCIHGNCSDRVAAYHC 581 Query: 407 ACPVTYTGKNCEV 445 C YTG NCEV Sbjct: 582 TCEPGYTGVNCEV 594 Score = 53.6 bits (123), Expect = 4e-07 Identities = 27/84 (32%), Positives = 43/84 (51%), Gaps = 1/84 (1%) Frame = +2 Query: 206 NVQNCFTCAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLCGPG-KCM 382 N+ CF+ N C++ G C + + Y C C PG+ G NC+ ++C+ C G C+ Sbjct: 558 NIDECFS---NPCIH-GNCSDRVA--AYHCTCEPGYTGVNCEVDIDNCQSHQCANGATCI 611 Query: 383 NTADSYKCACPVTYTGKNCEVKQL 454 + + Y C C +TGK C +L Sbjct: 612 SHTNGYSCLCFGNFTGKFCRQSRL 635 Score = 42.7 bits (96), Expect = 8e-04 Identities = 38/151 (25%), Positives = 61/151 (40%), Gaps = 12/151 (7%) Frame = +2 Query: 29 SPDQWTVLELNQPLYIGGVPDFDQLPIDLAGASGFVGCISMLILGNEE-------KNIMA 187 S W + E +YIGG+PD + ++ F GCI + L N+ N + Sbjct: 199 SASTWKI-EKGDVIYIGGLPDKQETELN---GGFFKGCIQDVRLNNQNLEFFPNPTNNAS 254 Query: 188 LALEKENV-QNCF---TCAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRP 355 L NV Q C +C N C N GVC + + C C G C+ + + C Sbjct: 255 LNPVLVNVTQGCAGDNSCKSNPCHNGGVCHSRWDD--FSCSCPALTSGKACEEV-QWCGF 311 Query: 356 GLCGPG-KCMNTADSYKCACPVTYTGKNCEV 445 C G +C ++C + G++ ++ Sbjct: 312 SPCPHGAQCQPVLQGFECIANAVFNGQSGQI 342 Score = 33.1 bits (72), Expect = 0.63 Identities = 14/37 (37%), Positives = 19/37 (51%), Gaps = 1/37 (2%) Frame = +2 Query: 344 SCRPGLC-GPGKCMNTADSYKCACPVTYTGKNCEVKQ 451 SC+ C G C + D + C+CP +GK CE Q Sbjct: 271 SCKSNPCHNGGVCHSRWDDFSCSCPALTSGKACEEVQ 307 Score = 29.9 bits (64), Expect = 5.9 Identities = 11/23 (47%), Positives = 14/23 (60%) Frame = +2 Query: 371 GKCMNTADSYKCACPVTYTGKNC 439 G+C+N SY+C C Y G NC Sbjct: 66 GRCINLWLSYQCDCHRPYEGPNC 88 >AK126775-1|BAC86684.1| 952|Homo sapiens protein ( Homo sapiens cDNA FLJ44823 fis, clone BRACE3046466, weakly similar to Crumbs protein homolog 1 precursor. ). Length = 952 Score = 58.8 bits (136), Expect = 1e-08 Identities = 23/74 (31%), Positives = 37/74 (50%), Gaps = 1/74 (1%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLCGPGKCMNTADS-YK 403 CAP+ CL++G C++ + C C PG+ G C+ + C C G+C D ++ Sbjct: 728 CAPSPCLHDGACRDLFD--AFACACGPGWEGPRCEAHVDPCHSAPCARGRCHTHPDGRFE 785 Query: 404 CACPVTYTGKNCEV 445 C CP + G C + Sbjct: 786 CRCPPGFGGPRCRL 799 Score = 39.9 bits (89), Expect = 0.006 Identities = 22/76 (28%), Positives = 32/76 (42%), Gaps = 5/76 (6%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLCG-PGKCM----NTA 391 C + CL+ G C + + GY+C C +GG +C C+ C C+ + Sbjct: 30 CLSDPCLHGGTCSDTVA--GYICRCPETWGGRDCSVQLTGCQGHTCPLAATCIPIFESGV 87 Query: 392 DSYKCACPVTYTGKNC 439 SY C CP G C Sbjct: 88 HSYVCHCPPGAHGPFC 103 Score = 37.9 bits (84), Expect = 0.022 Identities = 20/70 (28%), Positives = 29/70 (41%), Gaps = 4/70 (5%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDR----IGESCRPGLCGPGKCMNTAD 394 C+P+ C N G C +T + + C C F G C + G+ C P P C D Sbjct: 479 CSPDPCFNGGTC--LVTWNDFHCTCPANFTGPTCAQQLWCPGQPCLP----PATCEEVPD 532 Query: 395 SYKCACPVTY 424 + C T+ Sbjct: 533 GFVCVAEATF 542 Score = 35.5 bits (78), Expect = 0.12 Identities = 15/45 (33%), Positives = 22/45 (48%), Gaps = 1/45 (2%) Frame = +2 Query: 317 GNNCDRIGESCRPGLC-GPGKCMNTADSYKCACPVTYTGKNCEVK 448 G C+ + C C G C +T Y C CP T+ G++C V+ Sbjct: 20 GPTCEEDVDECLSDPCLHGGTCSDTVAGYICRCPETWGGRDCSVQ 64 Score = 35.5 bits (78), Expect = 0.12 Identities = 21/82 (25%), Positives = 31/82 (37%), Gaps = 2/82 (2%) Frame = +2 Query: 227 CAPNL-CLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLC-GPGKCMNTADSY 400 C+ N+ CL+ C+ C C G G C C C G C Sbjct: 806 CSLNVTCLDGSPCEGRSPAAN--CSCLEGLAGQRCQVPTLPCEANPCLNGGTCRAAGGVS 863 Query: 401 KCACPVTYTGKNCEVKQLIEYP 466 +C C ++G+ CEV + + P Sbjct: 864 ECICNARFSGQFCEVAKGLPLP 885 Score = 33.5 bits (73), Expect = 0.48 Identities = 12/34 (35%), Positives = 17/34 (50%), Gaps = 1/34 (2%) Frame = +2 Query: 341 ESCRPGLC-GPGKCMNTADSYKCACPVTYTGKNC 439 + C P C G C+ T + + C CP +TG C Sbjct: 477 DMCSPDPCFNGGTCLVTWNDFHCTCPANFTGPTC 510 >AB033063-1|BAA86551.2| 1268|Homo sapiens KIAA1237 protein protein. Length = 1268 Score = 58.8 bits (136), Expect = 1e-08 Identities = 27/68 (39%), Positives = 33/68 (48%), Gaps = 1/68 (1%) Frame = +2 Query: 224 TCAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLC-GPGKCMNTADSY 400 +CA N CL+NG C T GY C C P + G++C C C C NT S+ Sbjct: 875 SCAVNPCLHNGECVADNTSRGYHCRCPPSWQGDDCSVDVNECLSNPCPSTATCNNTQGSF 934 Query: 401 KCACPVTY 424 C CPV Y Sbjct: 935 ICKCPVGY 942 Score = 29.9 bits (64), Expect = 5.9 Identities = 14/37 (37%), Positives = 20/37 (54%), Gaps = 3/37 (8%) Frame = +2 Query: 344 SCRPGLC-GPGKCM--NTADSYKCACPVTYTGKNCEV 445 SC C G+C+ NT+ Y C CP ++ G +C V Sbjct: 875 SCAVNPCLHNGECVADNTSRGYHCRCPPSWQGDDCSV 911 >BC063822-1|AAH63822.1| 1009|Homo sapiens EGF-like, fibronectin type III and laminin G domains protein. Length = 1009 Score = 58.4 bits (135), Expect = 1e-08 Identities = 33/116 (28%), Positives = 52/116 (44%), Gaps = 6/116 (5%) Frame = +2 Query: 2 DNSGPFIAESPDQWTVLELNQPLYIGGVPDFDQLPIDLAGASGFVGCISMLILGNEEKNI 181 +N P +S Q++ + PLY+GG P L GF GC+ L + ++ Sbjct: 488 NNGTPVTGQSQGQYSKITFRTPLYLGGAPSAYWLVRATGTNRGFQGCVQSLAVNGRRIDM 547 Query: 182 ----MALALEKENVQNCFT--CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCD 331 + AL +V C + C C++ G C A+ Y+CLC GF G +C+ Sbjct: 548 RPWPLGKALSGADVGECSSGICDEASCIHGGTC-TAIKADSYICLCPLGFKGRHCE 602 Score = 49.2 bits (112), Expect = 9e-06 Identities = 28/99 (28%), Positives = 47/99 (47%), Gaps = 1/99 (1%) Frame = +2 Query: 41 WTVLELNQPLYIGGVPDFDQLPIDLAGASGFVGCISMLILGNEEKNIMALALEKENVQN- 217 +T ++ N ++IGGVP++D + + F G I +IL + ++ NV+N Sbjct: 725 FTQIKCNTDIFIGGVPNYDDVKKNSGVLKPFSGSIQKIILNDRTIHVKHDFTSGVNVENA 784 Query: 218 CFTCAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDR 334 C C + G C+ + GY C C GF G +C + Sbjct: 785 AHPCVRAPCAHGGSCRP--RKEGYDCDCPLGFEGLHCQK 821 Score = 37.5 bits (83), Expect = 0.029 Identities = 19/56 (33%), Positives = 28/56 (50%), Gaps = 7/56 (12%) Frame = +2 Query: 335 IGESCRPGLCGPGKCMN-------TADSYKCACPVTYTGKNCEVKQLIEYPAFTGS 481 +GE C G+C C++ ADSY C CP+ + G++CE + P F S Sbjct: 561 VGE-CSSGICDEASCIHGGTCTAIKADSYICLCPLGFKGRHCEDAFTLTIPQFRES 615 Score = 35.9 bits (79), Expect = 0.090 Identities = 19/66 (28%), Positives = 28/66 (42%), Gaps = 3/66 (4%) Frame = +2 Query: 317 GNNCDRIGESCRPGLCGPG-KCMNTADSYKCACPVTYTGKNCE--VKQLIEYPAFTGSA* 487 G N + C C G C + Y C CP+ + G +C+ + + IE P F G + Sbjct: 778 GVNVENAAHPCVRAPCAHGGSCRPRKEGYDCDCPLGFEGLHCQKAIIEAIEIPQFIGRSY 837 Query: 488 LAIKPP 505 L P Sbjct: 838 LTYDNP 843 Score = 35.1 bits (77), Expect = 0.16 Identities = 21/74 (28%), Positives = 36/74 (48%), Gaps = 1/74 (1%) Frame = +2 Query: 2 DNSGPFIAESPDQWTVLELNQPLYIGGVPDFDQLPIDLAGASGFVGCISMLILGNE-EKN 178 D+ G +SP L +N LY+GG+ + L + G VGCIS L + + Sbjct: 934 DDYGARTGKSPGMMRQLNINGALYVGGMKEI-ALHTNRQYMRGLVGCISHFTLSTDYHIS 992 Query: 179 IMALALEKENVQNC 220 ++ A++ +N+ C Sbjct: 993 LVEDAVDGKNINTC 1006 Score = 30.3 bits (65), Expect = 4.5 Identities = 16/55 (29%), Positives = 26/55 (47%), Gaps = 3/55 (5%) Frame = +2 Query: 347 CRPGLCGPGK-CMN--TADSYKCACPVTYTGKNCEVKQLIEYPAFTGSA*LAIKP 502 C LC C+N T +C C + G++C +I+YP F G + + +P Sbjct: 347 CDETLCSADSFCVNDYTWGGSRCQCTLGKGGESCSEDIVIQYPQFFGHSYVTFEP 401 >AK097549-1|BAC05096.1| 775|Homo sapiens protein ( Homo sapiens cDNA FLJ40230 fis, clone TESTI2022960, weakly similar to Drosophila melanogaster SP2353 mRNA. ). Length = 775 Score = 58.4 bits (135), Expect = 1e-08 Identities = 33/116 (28%), Positives = 52/116 (44%), Gaps = 6/116 (5%) Frame = +2 Query: 2 DNSGPFIAESPDQWTVLELNQPLYIGGVPDFDQLPIDLAGASGFVGCISMLILGNEEKNI 181 +N P +S Q++ + PLY+GG P L GF GC+ L + ++ Sbjct: 254 NNGTPVTGQSQGQYSKITFRTPLYLGGAPSAYWLVRATGTNRGFQGCVQSLAVNGRRIDM 313 Query: 182 ----MALALEKENVQNCFT--CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCD 331 + AL +V C + C C++ G C A+ Y+CLC GF G +C+ Sbjct: 314 RPWPLGKALSGADVGECSSGICDEASCIHGGTC-TAIKADSYICLCPLGFKGRHCE 368 Score = 49.2 bits (112), Expect = 9e-06 Identities = 28/99 (28%), Positives = 47/99 (47%), Gaps = 1/99 (1%) Frame = +2 Query: 41 WTVLELNQPLYIGGVPDFDQLPIDLAGASGFVGCISMLILGNEEKNIMALALEKENVQN- 217 +T ++ N ++IGGVP++D + + F G I +IL + ++ NV+N Sbjct: 491 FTQIKCNTDIFIGGVPNYDDVKKNSGVLKPFSGSIQKIILNDRTIHVKHDFTSGVNVENA 550 Query: 218 CFTCAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDR 334 C C + G C+ + GY C C GF G +C + Sbjct: 551 AHPCVRAPCAHGGSCRP--RKEGYDCDCPLGFEGLHCQK 587 Score = 37.5 bits (83), Expect = 0.029 Identities = 19/56 (33%), Positives = 28/56 (50%), Gaps = 7/56 (12%) Frame = +2 Query: 335 IGESCRPGLCGPGKCMN-------TADSYKCACPVTYTGKNCEVKQLIEYPAFTGS 481 +GE C G+C C++ ADSY C CP+ + G++CE + P F S Sbjct: 327 VGE-CSSGICDEASCIHGGTCTAIKADSYICLCPLGFKGRHCEDAFTLTIPQFRES 381 Score = 35.9 bits (79), Expect = 0.090 Identities = 19/66 (28%), Positives = 28/66 (42%), Gaps = 3/66 (4%) Frame = +2 Query: 317 GNNCDRIGESCRPGLCGPG-KCMNTADSYKCACPVTYTGKNCE--VKQLIEYPAFTGSA* 487 G N + C C G C + Y C CP+ + G +C+ + + IE P F G + Sbjct: 544 GVNVENAAHPCVRAPCAHGGSCRPRKEGYDCDCPLGFEGLHCQKAIIEAIEIPQFIGRSY 603 Query: 488 LAIKPP 505 L P Sbjct: 604 LTYDNP 609 Score = 35.1 bits (77), Expect = 0.16 Identities = 21/74 (28%), Positives = 36/74 (48%), Gaps = 1/74 (1%) Frame = +2 Query: 2 DNSGPFIAESPDQWTVLELNQPLYIGGVPDFDQLPIDLAGASGFVGCISMLILGNE-EKN 178 D+ G +SP L +N LY+GG+ + L + G VGCIS L + + Sbjct: 700 DDYGARTGKSPGMMRQLNINGALYVGGMKEI-ALHTNRQYMRGLVGCISHFTLSTDYHIS 758 Query: 179 IMALALEKENVQNC 220 ++ A++ +N+ C Sbjct: 759 LVEDAVDGKNINTC 772 Score = 30.3 bits (65), Expect = 4.5 Identities = 16/55 (29%), Positives = 26/55 (47%), Gaps = 3/55 (5%) Frame = +2 Query: 347 CRPGLCGPGK-CMN--TADSYKCACPVTYTGKNCEVKQLIEYPAFTGSA*LAIKP 502 C LC C+N T +C C + G++C +I+YP F G + + +P Sbjct: 113 CDETLCSADSFCVNDYTWGGSRCQCTLGKGGESCSEDIVIQYPQFFGHSYVTFEP 167 >Z12172-1|CAA78163.1| 383|Homo sapiens putative homeotic protein protein. Length = 383 Score = 58.0 bits (134), Expect = 2e-08 Identities = 25/69 (36%), Positives = 32/69 (46%), Gaps = 3/69 (4%) Frame = +2 Query: 242 CLNNGVC--QEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLC-GPGKCMNTADSYKCAC 412 C + G C E H CLC PGF GN C+ + SC P C G C + ++C C Sbjct: 138 CQHGGTCVDDEGRASHAS-CLCPPGFSGNFCEIVANSCTPNPCENDGVCTDIGGDFRCRC 196 Query: 413 PVTYTGKNC 439 P + K C Sbjct: 197 PAGFIDKTC 205 Score = 52.4 bits (120), Expect = 1e-06 Identities = 27/80 (33%), Positives = 39/80 (48%), Gaps = 2/80 (2%) Frame = +2 Query: 224 TCAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLC-GPGKCM-NTADS 397 +C PN C N+GVC + + + C C GF C R +C C G C+ +T S Sbjct: 173 SCTPNPCENDGVCTDIGGD--FRCRCPAGFIDKTCSRPVTNCASSPCQNGGTCLQHTQVS 230 Query: 398 YKCACPVTYTGKNCEVKQLI 457 Y+C C +TG C K+ + Sbjct: 231 YECLCKPEFTGLTCVKKRAL 250 Score = 47.2 bits (107), Expect = 4e-05 Identities = 22/71 (30%), Positives = 34/71 (47%), Gaps = 2/71 (2%) Frame = +2 Query: 242 CLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLC-GPGKCMN-TADSYKCACP 415 C+ + C L C+C G+ G CDR +C C G C++ Y+C+C Sbjct: 57 CVTSPGCLHGLCGEPGQCICTDGWDGELCDRDVRACSSAPCANNGTCVSLDGGLYECSCA 116 Query: 416 VTYTGKNCEVK 448 Y+GK+C+ K Sbjct: 117 PGYSGKDCQKK 127 Score = 46.0 bits (104), Expect = 8e-05 Identities = 26/79 (32%), Positives = 36/79 (45%), Gaps = 6/79 (7%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESC--RPGLC-GPGKCMN---T 388 C+ C NNG C +L Y C CAPG+ G +C + C C G C++ Sbjct: 92 CSSAPCANNGTCV-SLDGGLYECSCAPGYSGKDCQKKDGPCVINGSPCQHGGTCVDDEGR 150 Query: 389 ADSYKCACPVTYTGKNCEV 445 A C CP ++G CE+ Sbjct: 151 ASHASCLCPPGFSGNFCEI 169 Score = 34.7 bits (76), Expect = 0.21 Identities = 22/57 (38%), Positives = 28/57 (49%), Gaps = 3/57 (5%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGES--CRPGLCG-PGKCMNT 388 C P NG C++ VC C G+ G CD+ S C GLCG PG+C+ T Sbjct: 26 CFPACNPQNGFCED-----DNVCRCHVGWQGPLCDQCVTSPGCLHGLCGEPGQCICT 77 >U15981-1|AAA75365.1| 310|Homo sapiens dlk protein. Length = 310 Score = 58.0 bits (134), Expect = 2e-08 Identities = 25/69 (36%), Positives = 32/69 (46%), Gaps = 3/69 (4%) Frame = +2 Query: 242 CLNNGVC--QEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLC-GPGKCMNTADSYKCAC 412 C + G C E H CLC PGF GN C+ + SC P C G C + ++C C Sbjct: 138 CQHGGTCVDDEGRASHAS-CLCPPGFSGNFCEIVANSCTPNPCENDGVCTDIGGDFRCRC 196 Query: 413 PVTYTGKNC 439 P + K C Sbjct: 197 PAGFIDKTC 205 Score = 47.2 bits (107), Expect = 4e-05 Identities = 22/71 (30%), Positives = 34/71 (47%), Gaps = 2/71 (2%) Frame = +2 Query: 242 CLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLC-GPGKCMN-TADSYKCACP 415 C+ + C L C+C G+ G CDR +C C G C++ Y+C+C Sbjct: 57 CVTSPGCLHGLCGEPGQCICTDGWDGELCDRDVRACSSAPCANNGTCVSLDGGLYECSCA 116 Query: 416 VTYTGKNCEVK 448 Y+GK+C+ K Sbjct: 117 PGYSGKDCQKK 127 Score = 46.0 bits (104), Expect = 8e-05 Identities = 26/79 (32%), Positives = 36/79 (45%), Gaps = 6/79 (7%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESC--RPGLC-GPGKCMN---T 388 C+ C NNG C +L Y C CAPG+ G +C + C C G C++ Sbjct: 92 CSSAPCANNGTCV-SLDGGLYECSCAPGYSGKDCQKKDGPCVINGSPCQHGGTCVDDEGR 150 Query: 389 ADSYKCACPVTYTGKNCEV 445 A C CP ++G CE+ Sbjct: 151 ASHASCLCPPGFSGNFCEI 169 Score = 38.7 bits (86), Expect = 0.013 Identities = 23/57 (40%), Positives = 29/57 (50%), Gaps = 3/57 (5%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGES--CRPGLCG-PGKCMNT 388 C P NG C++ VC C PG+ G CD+ S C GLCG PG+C+ T Sbjct: 26 CFPACNPQNGFCED-----DNVCRCQPGWQGPLCDQCVTSPGCLHGLCGEPGQCICT 77 Score = 36.3 bits (80), Expect = 0.068 Identities = 18/54 (33%), Positives = 25/54 (46%), Gaps = 1/54 (1%) Frame = +2 Query: 224 TCAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLC-GPGKCM 382 +C PN C N+GVC + + + C C GF C R +C C G C+ Sbjct: 173 SCTPNPCENDGVCTDIGGD--FRCRCPAGFIDKTCSRPVTNCASSPCQNGGTCL 224 >U15979-1|AAA75364.1| 382|Homo sapiens dlk protein. Length = 382 Score = 58.0 bits (134), Expect = 2e-08 Identities = 25/69 (36%), Positives = 32/69 (46%), Gaps = 3/69 (4%) Frame = +2 Query: 242 CLNNGVC--QEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLC-GPGKCMNTADSYKCAC 412 C + G C E H CLC PGF GN C+ + SC P C G C + ++C C Sbjct: 138 CQHGGTCVDDEGRASHAS-CLCPPGFSGNFCEIVANSCTPNPCENDGVCTDIGGDFRCRC 196 Query: 413 PVTYTGKNC 439 P + K C Sbjct: 197 PAGFIDKTC 205 Score = 52.4 bits (120), Expect = 1e-06 Identities = 27/80 (33%), Positives = 39/80 (48%), Gaps = 2/80 (2%) Frame = +2 Query: 224 TCAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLC-GPGKCM-NTADS 397 +C PN C N+GVC + + + C C GF C R +C C G C+ +T S Sbjct: 173 SCTPNPCENDGVCTDIGGD--FRCRCPAGFIDKTCSRPVTNCASSPCQNGGTCLQHTQVS 230 Query: 398 YKCACPVTYTGKNCEVKQLI 457 Y+C C +TG C K+ + Sbjct: 231 YECLCKPEFTGLTCVKKRAL 250 Score = 47.2 bits (107), Expect = 4e-05 Identities = 22/71 (30%), Positives = 34/71 (47%), Gaps = 2/71 (2%) Frame = +2 Query: 242 CLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLC-GPGKCMN-TADSYKCACP 415 C+ + C L C+C G+ G CDR +C C G C++ Y+C+C Sbjct: 57 CVTSPGCLHGLCGEPGQCICTDGWDGELCDRDVRACSSAPCANNGTCVSLDGGLYECSCA 116 Query: 416 VTYTGKNCEVK 448 Y+GK+C+ K Sbjct: 117 PGYSGKDCQKK 127 Score = 46.0 bits (104), Expect = 8e-05 Identities = 26/79 (32%), Positives = 36/79 (45%), Gaps = 6/79 (7%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESC--RPGLC-GPGKCMN---T 388 C+ C NNG C +L Y C CAPG+ G +C + C C G C++ Sbjct: 92 CSSAPCANNGTCV-SLDGGLYECSCAPGYSGKDCQKKDGPCVINGSPCQHGGTCVDDEGR 150 Query: 389 ADSYKCACPVTYTGKNCEV 445 A C CP ++G CE+ Sbjct: 151 ASHASCLCPPGFSGNFCEI 169 Score = 38.7 bits (86), Expect = 0.013 Identities = 23/57 (40%), Positives = 29/57 (50%), Gaps = 3/57 (5%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGES--CRPGLCG-PGKCMNT 388 C P NG C++ VC C PG+ G CD+ S C GLCG PG+C+ T Sbjct: 26 CFPACNPQNGFCED-----DNVCRCQPGWQGPLCDQCVTSPGCLHGLCGEPGQCICT 77 >DQ309460-1|ABC26875.1| 231|Homo sapiens delta-like 1 protein. Length = 231 Score = 58.0 bits (134), Expect = 2e-08 Identities = 25/69 (36%), Positives = 32/69 (46%), Gaps = 3/69 (4%) Frame = +2 Query: 242 CLNNGVC--QEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLC-GPGKCMNTADSYKCAC 412 C + G C E H CLC PGF GN C+ + SC P C G C + ++C C Sbjct: 51 CQHGGTCVDDEGRASHAS-CLCPPGFSGNFCEIVANSCTPNPCENDGVCTDIGGDFRCRC 109 Query: 413 PVTYTGKNC 439 P + K C Sbjct: 110 PAGFIDKTC 118 Score = 52.4 bits (120), Expect = 1e-06 Identities = 27/80 (33%), Positives = 39/80 (48%), Gaps = 2/80 (2%) Frame = +2 Query: 224 TCAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLC-GPGKCM-NTADS 397 +C PN C N+GVC + + + C C GF C R +C C G C+ +T S Sbjct: 86 SCTPNPCENDGVCTDIGGD--FRCRCPAGFIDKTCSRPVTNCASSPCQNGGTCLQHTQVS 143 Query: 398 YKCACPVTYTGKNCEVKQLI 457 Y+C C +TG C K+ + Sbjct: 144 YECLCKPEFTGLTCVKKRAL 163 Score = 47.6 bits (108), Expect = 3e-05 Identities = 26/79 (32%), Positives = 37/79 (46%), Gaps = 6/79 (7%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESC--RPGLC-GPGKCMN---T 388 C+ C NNG C +L + Y C CAPG+ G +C + C C G C++ Sbjct: 5 CSSAPCANNGTCV-SLDDGLYECSCAPGYSGKDCQKKDGPCVINGSPCQHGGTCVDDEGR 63 Query: 389 ADSYKCACPVTYTGKNCEV 445 A C CP ++G CE+ Sbjct: 64 ASHASCLCPPGFSGNFCEI 82 Score = 30.3 bits (65), Expect = 4.5 Identities = 13/37 (35%), Positives = 21/37 (56%), Gaps = 2/37 (5%) Frame = +2 Query: 344 SCRPGLCGP-GKCMNTADS-YKCACPVTYTGKNCEVK 448 +C C G C++ D Y+C+C Y+GK+C+ K Sbjct: 4 ACSSAPCANNGTCVSLDDGLYECSCAPGYSGKDCQKK 40 >DQ126100-1|AAZ38943.1| 212|Homo sapiens brevideltin protein. Length = 212 Score = 58.0 bits (134), Expect = 2e-08 Identities = 25/69 (36%), Positives = 32/69 (46%), Gaps = 3/69 (4%) Frame = +2 Query: 242 CLNNGVC--QEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLC-GPGKCMNTADSYKCAC 412 C + G C E H CLC PGF GN C+ + SC P C G C + ++C C Sbjct: 138 CQHGGTCVDDEGRASHAS-CLCPPGFSGNFCEIVANSCTPNPCENDGVCTDIGGDFRCRC 196 Query: 413 PVTYTGKNC 439 P + K C Sbjct: 197 PAGFIDKTC 205 Score = 50.0 bits (114), Expect = 5e-06 Identities = 23/71 (32%), Positives = 35/71 (49%), Gaps = 2/71 (2%) Frame = +2 Query: 242 CLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLC-GPGKCMNTADS-YKCACP 415 C+ + C L C+C G+ G CDR +C C G C++ D Y+C+C Sbjct: 57 CVTSPGCLHGLCGEPGQCICTDGWDGELCDRDVRACSSAPCANNGTCVSLDDGLYECSCA 116 Query: 416 VTYTGKNCEVK 448 Y+GK+C+ K Sbjct: 117 PGYSGKDCQKK 127 Score = 47.6 bits (108), Expect = 3e-05 Identities = 26/79 (32%), Positives = 37/79 (46%), Gaps = 6/79 (7%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESC--RPGLC-GPGKCMN---T 388 C+ C NNG C +L + Y C CAPG+ G +C + C C G C++ Sbjct: 92 CSSAPCANNGTCV-SLDDGLYECSCAPGYSGKDCQKKDGPCVINGSPCQHGGTCVDDEGR 150 Query: 389 ADSYKCACPVTYTGKNCEV 445 A C CP ++G CE+ Sbjct: 151 ASHASCLCPPGFSGNFCEI 169 Score = 38.7 bits (86), Expect = 0.013 Identities = 23/57 (40%), Positives = 29/57 (50%), Gaps = 3/57 (5%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGES--CRPGLCG-PGKCMNT 388 C P NG C++ VC C PG+ G CD+ S C GLCG PG+C+ T Sbjct: 26 CFPACNPQNGFCED-----DNVCRCQPGWQGPLCDQCVTSPGCLHGLCGEPGQCICT 77 Score = 30.3 bits (65), Expect = 4.5 Identities = 13/35 (37%), Positives = 18/35 (51%) Frame = +2 Query: 224 TCAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNC 328 +C PN C N+GVC + + + C C GF C Sbjct: 173 SCTPNPCENDGVCTDIGGD--FRCRCPAGFIDKTC 205 >DQ017081-1|AAY40461.1| 315|Homo sapiens secredeltin protein. Length = 315 Score = 58.0 bits (134), Expect = 2e-08 Identities = 25/69 (36%), Positives = 32/69 (46%), Gaps = 3/69 (4%) Frame = +2 Query: 242 CLNNGVC--QEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLC-GPGKCMNTADSYKCAC 412 C + G C E H CLC PGF GN C+ + SC P C G C + ++C C Sbjct: 138 CQHGGTCVDDEGRASHAS-CLCPPGFSGNFCEIVANSCTPNPCENDGVCTDIGGDFRCRC 196 Query: 413 PVTYTGKNC 439 P + K C Sbjct: 197 PAGFIDKTC 205 Score = 50.0 bits (114), Expect = 5e-06 Identities = 23/71 (32%), Positives = 35/71 (49%), Gaps = 2/71 (2%) Frame = +2 Query: 242 CLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLC-GPGKCMNTADS-YKCACP 415 C+ + C L C+C G+ G CDR +C C G C++ D Y+C+C Sbjct: 57 CVTSPGCLHGLCGEPGQCICTDGWDGELCDRDVRACSSAPCANNGTCVSLDDGLYECSCA 116 Query: 416 VTYTGKNCEVK 448 Y+GK+C+ K Sbjct: 117 PGYSGKDCQKK 127 Score = 47.6 bits (108), Expect = 3e-05 Identities = 26/79 (32%), Positives = 37/79 (46%), Gaps = 6/79 (7%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESC--RPGLC-GPGKCMN---T 388 C+ C NNG C +L + Y C CAPG+ G +C + C C G C++ Sbjct: 92 CSSAPCANNGTCV-SLDDGLYECSCAPGYSGKDCQKKDGPCVINGSPCQHGGTCVDDEGR 150 Query: 389 ADSYKCACPVTYTGKNCEV 445 A C CP ++G CE+ Sbjct: 151 ASHASCLCPPGFSGNFCEI 169 Score = 38.7 bits (86), Expect = 0.013 Identities = 23/57 (40%), Positives = 29/57 (50%), Gaps = 3/57 (5%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGES--CRPGLCG-PGKCMNT 388 C P NG C++ VC C PG+ G CD+ S C GLCG PG+C+ T Sbjct: 26 CFPACNPQNGFCED-----DNVCRCQPGWQGPLCDQCVTSPGCLHGLCGEPGQCICT 77 Score = 32.3 bits (70), Expect = 1.1 Identities = 14/37 (37%), Positives = 19/37 (51%) Frame = +2 Query: 224 TCAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDR 334 +C PN C N+GVC + + + C C GF C R Sbjct: 173 SCTPNPCENDGVCTDIGGD--FRCRCPAGFIDKTCSR 207 >BC014015-1|AAH14015.1| 383|Homo sapiens delta-like 1 homolog (Drosophila) protein. Length = 383 Score = 58.0 bits (134), Expect = 2e-08 Identities = 25/69 (36%), Positives = 32/69 (46%), Gaps = 3/69 (4%) Frame = +2 Query: 242 CLNNGVC--QEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLC-GPGKCMNTADSYKCAC 412 C + G C E H CLC PGF GN C+ + SC P C G C + ++C C Sbjct: 138 CQHGGTCVDDEGRASHAS-CLCPPGFSGNFCEIVANSCTPNPCENDGVCTDIGGDFRCRC 196 Query: 413 PVTYTGKNC 439 P + K C Sbjct: 197 PAGFIDKTC 205 Score = 52.4 bits (120), Expect = 1e-06 Identities = 27/80 (33%), Positives = 39/80 (48%), Gaps = 2/80 (2%) Frame = +2 Query: 224 TCAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLC-GPGKCM-NTADS 397 +C PN C N+GVC + + + C C GF C R +C C G C+ +T S Sbjct: 173 SCTPNPCENDGVCTDIGGD--FRCRCPAGFIDKTCSRPVTNCASSPCQNGGTCLQHTQVS 230 Query: 398 YKCACPVTYTGKNCEVKQLI 457 Y+C C +TG C K+ + Sbjct: 231 YECLCKPEFTGLTCVKKRAL 250 Score = 50.0 bits (114), Expect = 5e-06 Identities = 23/71 (32%), Positives = 35/71 (49%), Gaps = 2/71 (2%) Frame = +2 Query: 242 CLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLC-GPGKCMNTADS-YKCACP 415 C+ + C L C+C G+ G CDR +C C G C++ D Y+C+C Sbjct: 57 CVTSPGCLHGLCGEPGQCICTDGWDGELCDRDVRACSSAPCANNGTCVSLDDGLYECSCA 116 Query: 416 VTYTGKNCEVK 448 Y+GK+C+ K Sbjct: 117 PGYSGKDCQKK 127 Score = 47.6 bits (108), Expect = 3e-05 Identities = 26/79 (32%), Positives = 37/79 (46%), Gaps = 6/79 (7%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESC--RPGLC-GPGKCMN---T 388 C+ C NNG C +L + Y C CAPG+ G +C + C C G C++ Sbjct: 92 CSSAPCANNGTCV-SLDDGLYECSCAPGYSGKDCQKKDGPCVINGSPCQHGGTCVDDEGR 150 Query: 389 ADSYKCACPVTYTGKNCEV 445 A C CP ++G CE+ Sbjct: 151 ASHASCLCPPGFSGNFCEI 169 Score = 38.7 bits (86), Expect = 0.013 Identities = 23/57 (40%), Positives = 29/57 (50%), Gaps = 3/57 (5%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGES--CRPGLCG-PGKCMNT 388 C P NG C++ VC C PG+ G CD+ S C GLCG PG+C+ T Sbjct: 26 CFPACNPQNGFCED-----DNVCRCQPGWQGPLCDQCVTSPGCLHGLCGEPGQCICT 77 >BC013197-1|AAH13197.1| 383|Homo sapiens delta-like 1 homolog (Drosophila) protein. Length = 383 Score = 58.0 bits (134), Expect = 2e-08 Identities = 25/69 (36%), Positives = 32/69 (46%), Gaps = 3/69 (4%) Frame = +2 Query: 242 CLNNGVC--QEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLC-GPGKCMNTADSYKCAC 412 C + G C E H CLC PGF GN C+ + SC P C G C + ++C C Sbjct: 138 CQHGGTCVDDEGRASHAS-CLCPPGFSGNFCEIVANSCTPNPCENDGVCTDIGGDFRCRC 196 Query: 413 PVTYTGKNC 439 P + K C Sbjct: 197 PAGFIDKTC 205 Score = 52.4 bits (120), Expect = 1e-06 Identities = 27/80 (33%), Positives = 39/80 (48%), Gaps = 2/80 (2%) Frame = +2 Query: 224 TCAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLC-GPGKCM-NTADS 397 +C PN C N+GVC + + + C C GF C R +C C G C+ +T S Sbjct: 173 SCTPNPCENDGVCTDIGGD--FRCRCPAGFIDKTCSRPVTNCASSPCQNGGTCLQHTQVS 230 Query: 398 YKCACPVTYTGKNCEVKQLI 457 Y+C C +TG C K+ + Sbjct: 231 YECLCKPEFTGLTCVKKRAL 250 Score = 50.0 bits (114), Expect = 5e-06 Identities = 23/71 (32%), Positives = 35/71 (49%), Gaps = 2/71 (2%) Frame = +2 Query: 242 CLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLC-GPGKCMNTADS-YKCACP 415 C+ + C L C+C G+ G CDR +C C G C++ D Y+C+C Sbjct: 57 CVTSPGCLHGLCGEPGQCICTDGWDGELCDRDVRACSSAPCANNGTCVSLDDGLYECSCA 116 Query: 416 VTYTGKNCEVK 448 Y+GK+C+ K Sbjct: 117 PGYSGKDCQKK 127 Score = 47.6 bits (108), Expect = 3e-05 Identities = 26/79 (32%), Positives = 37/79 (46%), Gaps = 6/79 (7%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESC--RPGLC-GPGKCMN---T 388 C+ C NNG C +L + Y C CAPG+ G +C + C C G C++ Sbjct: 92 CSSAPCANNGTCV-SLDDGLYECSCAPGYSGKDCQKKDGPCVINGSPCQHGGTCVDDEGR 150 Query: 389 ADSYKCACPVTYTGKNCEV 445 A C CP ++G CE+ Sbjct: 151 ASHASCLCPPGFSGNFCEI 169 Score = 38.7 bits (86), Expect = 0.013 Identities = 23/57 (40%), Positives = 29/57 (50%), Gaps = 3/57 (5%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGES--CRPGLCG-PGKCMNT 388 C P NG C++ VC C PG+ G CD+ S C GLCG PG+C+ T Sbjct: 26 CFPACNPQNGFCED-----DNVCRCQPGWQGPLCDQCVTSPGCLHGLCGEPGQCICT 77 >BC007741-1|AAH07741.1| 383|Homo sapiens delta-like 1 homolog (Drosophila) protein. Length = 383 Score = 58.0 bits (134), Expect = 2e-08 Identities = 25/69 (36%), Positives = 32/69 (46%), Gaps = 3/69 (4%) Frame = +2 Query: 242 CLNNGVC--QEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLC-GPGKCMNTADSYKCAC 412 C + G C E H CLC PGF GN C+ + SC P C G C + ++C C Sbjct: 138 CQHGGTCVDDEGRASHAS-CLCPPGFSGNFCEIVANSCTPNPCENDGVCTDIGGDFRCRC 196 Query: 413 PVTYTGKNC 439 P + K C Sbjct: 197 PAGFIDKTC 205 Score = 52.4 bits (120), Expect = 1e-06 Identities = 27/80 (33%), Positives = 39/80 (48%), Gaps = 2/80 (2%) Frame = +2 Query: 224 TCAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLC-GPGKCM-NTADS 397 +C PN C N+GVC + + + C C GF C R +C C G C+ +T S Sbjct: 173 SCTPNPCENDGVCTDIGGD--FRCRCPAGFIDKTCSRPVTNCASSPCQNGGTCLQHTQVS 230 Query: 398 YKCACPVTYTGKNCEVKQLI 457 Y+C C +TG C K+ + Sbjct: 231 YECLCKPEFTGLTCVKKRAL 250 Score = 50.0 bits (114), Expect = 5e-06 Identities = 23/71 (32%), Positives = 35/71 (49%), Gaps = 2/71 (2%) Frame = +2 Query: 242 CLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLC-GPGKCMNTADS-YKCACP 415 C+ + C L C+C G+ G CDR +C C G C++ D Y+C+C Sbjct: 57 CVTSPGCLHGLCGEPGQCICTDGWDGELCDRDVRACSSAPCANNGTCVSLDDGLYECSCA 116 Query: 416 VTYTGKNCEVK 448 Y+GK+C+ K Sbjct: 117 PGYSGKDCQKK 127 Score = 47.6 bits (108), Expect = 3e-05 Identities = 26/79 (32%), Positives = 37/79 (46%), Gaps = 6/79 (7%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESC--RPGLC-GPGKCMN---T 388 C+ C NNG C +L + Y C CAPG+ G +C + C C G C++ Sbjct: 92 CSSAPCANNGTCV-SLDDGLYECSCAPGYSGKDCQKKDGPCVINGSPCQHGGTCVDDEGR 150 Query: 389 ADSYKCACPVTYTGKNCEV 445 A C CP ++G CE+ Sbjct: 151 ASHASCLCPPGFSGNFCEI 169 Score = 38.7 bits (86), Expect = 0.013 Identities = 23/57 (40%), Positives = 29/57 (50%), Gaps = 3/57 (5%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGES--CRPGLCG-PGKCMNT 388 C P NG C++ VC C PG+ G CD+ S C GLCG PG+C+ T Sbjct: 26 CFPACNPQNGFCED-----DNVCRCQPGWQGPLCDQCVTSPGCLHGLCGEPGQCICT 77 >AL137311-1|CAB70690.1| 252|Homo sapiens hypothetical protein protein. Length = 252 Score = 58.0 bits (134), Expect = 2e-08 Identities = 28/74 (37%), Positives = 37/74 (50%), Gaps = 1/74 (1%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLCGPG-KCMNTADSYK 403 CA CLN C ++ +G C+CAPGF G CD C C G C++ + Y Sbjct: 62 CANVSCLNGATC-DSDGLNG-TCICAPGFTGEECDIDINECDSNPCHHGGSCLDQPNGYN 119 Query: 404 CACPVTYTGKNCEV 445 C CP + G NCE+ Sbjct: 120 CHCPHGWVGANCEI 133 Score = 45.2 bits (102), Expect = 1e-04 Identities = 18/54 (33%), Positives = 25/54 (46%), Gaps = 1/54 (1%) Frame = +2 Query: 287 YVCLCAPGFGGNNCDRIGESCRPGLC-GPGKCMNTADSYKCACPVTYTGKNCEV 445 Y CLC PG+ G C+ C C C + + Y+C C Y G +CE+ Sbjct: 4 YKCLCDPGYHGLYCEEEYNECLSAPCLNAATCRDLVNGYECVCLAEYKGTHCEL 57 Score = 43.6 bits (98), Expect = 4e-04 Identities = 20/74 (27%), Positives = 35/74 (47%), Gaps = 1/74 (1%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLCGPG-KCMNTADSYK 403 C CLN C++ + +GY C+C + G +C+ + C C G C + + Sbjct: 24 CLSAPCLNAATCRDLV--NGYECVCLAEYKGTHCELYKDPCANVSCLNGATCDSDGLNGT 81 Query: 404 CACPVTYTGKNCEV 445 C C +TG+ C++ Sbjct: 82 CICAPGFTGEECDI 95 >AY714129-1|AAU94938.1| 4186|Homo sapiens anchor protein protein. Length = 4186 Score = 57.2 bits (132), Expect = 3e-08 Identities = 30/79 (37%), Positives = 40/79 (50%), Gaps = 6/79 (7%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGES--CRPGLC-GPGKCMNTAD- 394 C N C N G C A E GY C+C P F G +C+ E+ C PG+C G C + + Sbjct: 1509 CYSNPCRNGGAC--ARREGGYTCVCRPRFTGEDCELDTEAGRCVPGVCRNGGTCTDAPNG 1566 Query: 395 SYKCACPV--TYTGKNCEV 445 ++C CP + G CEV Sbjct: 1567 GFRCQCPAGGAFEGPRCEV 1585 Score = 45.6 bits (103), Expect = 1e-04 Identities = 28/98 (28%), Positives = 42/98 (42%), Gaps = 5/98 (5%) Frame = +2 Query: 50 LELNQPLYIGGVPDF-DQLPIDLAGASGFVGCISMLILGNEEKNIMALALEKENVQNCFT 226 L+L PL +GGVP+ + P+ F+GC+ L + ++ A + C Sbjct: 1735 LDLTGPLLLGGVPNLPENFPVS---HKDFIGCMRDLHIDGRRVDMAAFVANNGTMAGCQA 1791 Query: 227 ----CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNC 328 C C N+G C E + C C GFGG +C Sbjct: 1792 KLHFCDSGPCKNSGFCSERWGS--FSCDCPVGFGGKDC 1827 Score = 44.4 bits (100), Expect = 3e-04 Identities = 19/55 (34%), Positives = 26/55 (47%), Gaps = 1/55 (1%) Frame = +2 Query: 284 GYVCLCAPGFGGNNCDRIGESCRPGLC-GPGKCMNTADSYKCACPVTYTGKNCEV 445 G C C PGF G+ C+ + C C G C Y C C +TG++CE+ Sbjct: 1488 GLRCRCPPGFTGDFCETELDLCYSNPCRNGGACARREGGYTCVCRPRFTGEDCEL 1542 Score = 41.1 bits (92), Expect = 0.002 Identities = 21/58 (36%), Positives = 28/58 (48%), Gaps = 7/58 (12%) Frame = +2 Query: 227 CAPNLCLNNGVCQEAL-TEHGYVCLCAPGFGGNNCD-RIGESCRPG-----LCGPGKC 379 C N C N G C+ HGY C C G+ G++C+ R+ + C G CGP C Sbjct: 2055 CLLNPCQNQGSCRHLPGAPHGYTCDCVGGYFGHHCEHRMDQQCPRGWWGSPTCGPCNC 2112 Score = 38.7 bits (86), Expect = 0.013 Identities = 37/137 (27%), Positives = 53/137 (38%), Gaps = 12/137 (8%) Frame = +2 Query: 68 LYIGGVP--DFDQLPIDLAGASGFVGCISMLILGNEEKNIMALALEKENVQ---NCFT-- 226 L++GG+P ++ P G VGCI + LG+ AL V C Sbjct: 1965 LHVGGLPPGSAEEAP------QGLVGCIQGVWLGSTPSGSPALLPPSHRVNAEPGCVVTN 2018 Query: 227 -CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLC-GPGKCMN---TA 391 CA C + C++ + C C PG+ G C ++C C G C + Sbjct: 2019 ACASGPCPPHADCRDLWQT--FSCTCQPGYYGPGC---VDACLLNPCQNQGSCRHLPGAP 2073 Query: 392 DSYKCACPVTYTGKNCE 442 Y C C Y G +CE Sbjct: 2074 HGYTCDCVGGYFGHHCE 2090 Score = 32.3 bits (70), Expect = 1.1 Identities = 16/51 (31%), Positives = 23/51 (45%), Gaps = 6/51 (11%) Frame = +2 Query: 311 FGGNNCDRIGESCRPGLCGPGKCMNTA------DSYKCACPVTYTGKNCEV 445 F NN G + C G C N+ S+ C CPV + GK+C++ Sbjct: 1779 FVANNGTMAGCQAKLHFCDSGPCKNSGFCSERWGSFSCDCPVGFGGKDCQL 1829 >AL450324-2|CAI13283.1| 186|Homo sapiens protein ( Human DNA sequence from clone RP11-307F22 on chromosome 6. ). Length = 186 Score = 57.2 bits (132), Expect = 3e-08 Identities = 24/78 (30%), Positives = 35/78 (44%) Frame = +2 Query: 215 NCFTCAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLCGPGKCMNTAD 394 N C CL++GVC + + Y C C GF G +C+ C C G+C + Sbjct: 44 NLDECLSEPCLHDGVCIDGINH--YTCDCKSGFFGTHCETNANDCLSNPCLHGRCTELIN 101 Query: 395 SYKCACPVTYTGKNCEVK 448 Y C+C T C++K Sbjct: 102 EYPCSCDADGTSTQCKIK 119 Score = 43.2 bits (97), Expect = 6e-04 Identities = 26/77 (33%), Positives = 30/77 (38%), Gaps = 1/77 (1%) Frame = +2 Query: 215 NCFTCAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLC-GPGKCMNTA 391 N C N CL+ G C E + E Y C C C C C G C +A Sbjct: 82 NANDCLSNPCLH-GRCTELINE--YPCSCDADGTSTQCKIKINDCTSIPCMNEGFCQKSA 138 Query: 392 DSYKCACPVTYTGKNCE 442 + C CP YTG CE Sbjct: 139 HGFTCICPRGYTGAYCE 155 Score = 40.3 bits (90), Expect = 0.004 Identities = 16/53 (30%), Positives = 27/53 (50%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLCGPGKCMN 385 C C+N G CQ++ HG+ C+C G+ G C++ ++C C+N Sbjct: 123 CTSIPCMNEGFCQKSA--HGFTCICPRGYTGAYCEKSIDNCAEPELNSVICLN 173 >AF231023-1|AAF61929.1| 3312|Homo sapiens protocadherin Flamingo 1 protein. Length = 3312 Score = 57.2 bits (132), Expect = 3e-08 Identities = 30/79 (37%), Positives = 40/79 (50%), Gaps = 6/79 (7%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGES--CRPGLC-GPGKCMNTAD- 394 C N C N G C A E GY C+C P F G +C+ E+ C PG+C G C + + Sbjct: 1439 CYSNPCRNGGAC--ARREGGYTCVCRPRFTGEDCELDTEAGRCVPGVCRNGGTCTDAPNG 1496 Query: 395 SYKCACPV--TYTGKNCEV 445 ++C CP + G CEV Sbjct: 1497 GFRCQCPAGGAFEGPRCEV 1515 Score = 45.6 bits (103), Expect = 1e-04 Identities = 28/98 (28%), Positives = 42/98 (42%), Gaps = 5/98 (5%) Frame = +2 Query: 50 LELNQPLYIGGVPDF-DQLPIDLAGASGFVGCISMLILGNEEKNIMALALEKENVQNCFT 226 L+L PL +GGVP+ + P+ F+GC+ L + ++ A + C Sbjct: 1665 LDLTGPLLLGGVPNLPENFPVS---HKDFIGCMRDLHIDGRRVDMAAFVANNGTMAGCQA 1721 Query: 227 ----CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNC 328 C C N+G C E + C C GFGG +C Sbjct: 1722 KLHFCDSGPCKNSGFCSERWGS--FSCDCPVGFGGKDC 1757 Score = 44.4 bits (100), Expect = 3e-04 Identities = 19/55 (34%), Positives = 26/55 (47%), Gaps = 1/55 (1%) Frame = +2 Query: 284 GYVCLCAPGFGGNNCDRIGESCRPGLC-GPGKCMNTADSYKCACPVTYTGKNCEV 445 G C C PGF G+ C+ + C C G C Y C C +TG++CE+ Sbjct: 1418 GLRCRCPPGFTGDFCETELDLCYSNPCRNGGACARREGGYTCVCRPRFTGEDCEL 1472 Score = 41.1 bits (92), Expect = 0.002 Identities = 21/58 (36%), Positives = 28/58 (48%), Gaps = 7/58 (12%) Frame = +2 Query: 227 CAPNLCLNNGVCQEAL-TEHGYVCLCAPGFGGNNCD-RIGESCRPG-----LCGPGKC 379 C N C N G C+ HGY C C G+ G++C+ R+ + C G CGP C Sbjct: 1985 CLLNPCQNQGSCRHLPGAPHGYTCDCVGGYFGHHCEHRMDQQCPRGWWGSPTCGPCNC 2042 Score = 38.7 bits (86), Expect = 0.013 Identities = 37/137 (27%), Positives = 53/137 (38%), Gaps = 12/137 (8%) Frame = +2 Query: 68 LYIGGVP--DFDQLPIDLAGASGFVGCISMLILGNEEKNIMALALEKENVQ---NCFT-- 226 L++GG+P ++ P G VGCI + LG+ AL V C Sbjct: 1895 LHVGGLPPGSAEEAP------QGLVGCIQGVWLGSTPSGSPALLPPSHRVNAEPGCVVTN 1948 Query: 227 -CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLC-GPGKCMN---TA 391 CA C + C++ + C C PG+ G C ++C C G C + Sbjct: 1949 ACASGPCPPHADCRDLWQT--FSCTCQPGYYGPGC---VDACLLNPCQNQGSCRHLPGAP 2003 Query: 392 DSYKCACPVTYTGKNCE 442 Y C C Y G +CE Sbjct: 2004 HGYTCDCVGGYFGHHCE 2020 Score = 32.3 bits (70), Expect = 1.1 Identities = 16/51 (31%), Positives = 23/51 (45%), Gaps = 6/51 (11%) Frame = +2 Query: 311 FGGNNCDRIGESCRPGLCGPGKCMNTA------DSYKCACPVTYTGKNCEV 445 F NN G + C G C N+ S+ C CPV + GK+C++ Sbjct: 1709 FVANNGTMAGCQAKLHFCDSGPCKNSGFCSERWGSFSCDCPVGFGGKDCQL 1759 >AB024578-1|BAA88952.1| 78|Homo sapiens notch4 protein. Length = 78 Score = 57.2 bits (132), Expect = 3e-08 Identities = 24/72 (33%), Positives = 35/72 (48%), Gaps = 1/72 (1%) Frame = +2 Query: 203 ENVQNCFTCAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLCGPGK-C 379 E+V C P C N G CQ + + C+C G+GG +C+ + C C PG C Sbjct: 5 EDVDQCEAQGPPHCRNGGTCQNSAGS--FHCVCVSGWGGTSCEENLDDCIAATCAPGSTC 62 Query: 380 MNTADSYKCACP 415 ++ S+ C CP Sbjct: 63 IDRVGSFSCLCP 74 Score = 29.9 bits (64), Expect = 5.9 Identities = 15/42 (35%), Positives = 21/42 (50%), Gaps = 1/42 (2%) Frame = +2 Query: 320 NNCDRIGES-CRPGLCGPGKCMNTADSYKCACPVTYTGKNCE 442 + C+ G CR G G C N+A S+ C C + G +CE Sbjct: 8 DQCEAQGPPHCRNG----GTCQNSAGSFHCVCVSGWGGTSCE 45 >BX537434-1|CAD97676.1| 236|Homo sapiens hypothetical protein protein. Length = 236 Score = 56.0 bits (129), Expect = 8e-08 Identities = 35/99 (35%), Positives = 44/99 (44%), Gaps = 6/99 (6%) Frame = +2 Query: 203 ENVQNCFTCAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCD-RIGESC---RPGLCGP 370 E Q+ C N C N G C C CA GF G +C C RP L G Sbjct: 21 EYCQHRDPCEKNRCQNGGTCVAQAMLGKATCRCASGFTGEDCQYSTSHPCFVSRPCLNG- 79 Query: 371 GKC-MNTADSYKCACPVTYTGKNCE-VKQLIEYPAFTGS 481 G C M + D+Y+C C V +TGK C+ + +P GS Sbjct: 80 GTCHMLSRDTYECTCQVGFTGKECQWTDACLSHPCANGS 118 Score = 50.0 bits (114), Expect = 5e-06 Identities = 24/74 (32%), Positives = 33/74 (44%), Gaps = 2/74 (2%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCR-PGLCGPG-KCMNTADSY 400 C + C N C + + C C GF G C+ C PG C G C+N SY Sbjct: 109 CLSHPCANGSTCTTVANQ--FSCKCLTGFTGQKCETDVNECDIPGHCQHGGTCLNLPGSY 166 Query: 401 KCACPVTYTGKNCE 442 +C C +TG+ C+ Sbjct: 167 QCQCLQGFTGQYCD 180 Score = 41.5 bits (93), Expect = 0.002 Identities = 21/62 (33%), Positives = 26/62 (41%), Gaps = 2/62 (3%) Frame = +2 Query: 233 PNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLC-GPGKCMNTAD-SYKC 406 P C + G C Y C C GF G CD + C P C G C T D +++C Sbjct: 150 PGHCQHGGTCLNL--PGSYQCQCLQGFTGQYCDSLYVPCAPSPCVNGGTCRQTGDFTFEC 207 Query: 407 AC 412 C Sbjct: 208 NC 209 >BC090943-1|AAH90943.1| 249|Homo sapiens NOTCH2NL protein protein. Length = 249 Score = 56.0 bits (129), Expect = 8e-08 Identities = 35/99 (35%), Positives = 44/99 (44%), Gaps = 6/99 (6%) Frame = +2 Query: 203 ENVQNCFTCAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCD-RIGESC---RPGLCGP 370 E Q+ C N C N G C C CA GF G +C C RP L G Sbjct: 34 EYCQHRDPCEKNRCQNGGTCVAQAMLGKATCRCASGFTGEDCQYSTSHPCFVSRPCLNG- 92 Query: 371 GKC-MNTADSYKCACPVTYTGKNCE-VKQLIEYPAFTGS 481 G C M + D+Y+C C V +TGK C+ + +P GS Sbjct: 93 GTCHMLSRDTYECTCQVGFTGKECQWTDACLSHPCANGS 131 Score = 49.6 bits (113), Expect = 7e-06 Identities = 24/74 (32%), Positives = 33/74 (44%), Gaps = 2/74 (2%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCR-PGLCGPGK-CMNTADSY 400 C + C N C + + C C GF G C+ C PG C G C+N SY Sbjct: 122 CLSHPCANGSTCTTVANQ--FSCKCLTGFTGQKCETDVNECDIPGHCQHGGICLNLPGSY 179 Query: 401 KCACPVTYTGKNCE 442 +C C +TG+ C+ Sbjct: 180 QCQCLQGFTGQYCD 193 Score = 42.7 bits (96), Expect = 8e-04 Identities = 21/62 (33%), Positives = 27/62 (43%), Gaps = 2/62 (3%) Frame = +2 Query: 233 PNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLC-GPGKCMNTAD-SYKC 406 P C + G+C Y C C GF G CD + C P C G C T D +++C Sbjct: 163 PGHCQHGGICLNL--PGSYQCQCLQGFTGQYCDSLYVPCAPSPCVNGGTCRQTGDFTFEC 220 Query: 407 AC 412 C Sbjct: 221 NC 222 >BC084572-1|AAH84572.1| 343|Homo sapiens NOTCH2NL protein protein. Length = 343 Score = 56.0 bits (129), Expect = 8e-08 Identities = 35/99 (35%), Positives = 44/99 (44%), Gaps = 6/99 (6%) Frame = +2 Query: 203 ENVQNCFTCAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCD-RIGESC---RPGLCGP 370 E Q+ C N C N G C C CA GF G +C C RP L G Sbjct: 128 EYCQHRDPCEKNRCQNGGTCVAQAMLGKATCRCASGFTGEDCQYSTSHPCFVSRPCLNG- 186 Query: 371 GKC-MNTADSYKCACPVTYTGKNCE-VKQLIEYPAFTGS 481 G C M + D+Y+C C V +TGK C+ + +P GS Sbjct: 187 GTCHMLSRDTYECTCQVGFTGKECQWTDACLSHPCANGS 225 Score = 50.0 bits (114), Expect = 5e-06 Identities = 24/74 (32%), Positives = 33/74 (44%), Gaps = 2/74 (2%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCR-PGLCGPG-KCMNTADSY 400 C + C N C + + C C GF G C+ C PG C G C+N SY Sbjct: 216 CLSHPCANGSTCTTVANQ--FSCKCLTGFTGQKCETDVNECDIPGHCQHGGTCLNLPGSY 273 Query: 401 KCACPVTYTGKNCE 442 +C C +TG+ C+ Sbjct: 274 QCQCLQGFTGQYCD 287 Score = 41.5 bits (93), Expect = 0.002 Identities = 21/62 (33%), Positives = 26/62 (41%), Gaps = 2/62 (3%) Frame = +2 Query: 233 PNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLC-GPGKCMNTAD-SYKC 406 P C + G C Y C C GF G CD + C P C G C T D +++C Sbjct: 257 PGHCQHGGTCLNL--PGSYQCQCLQGFTGQYCDSLYVPCAPSPCVNGGTCRQTGDFTFEC 314 Query: 407 AC 412 C Sbjct: 315 NC 316 >BC065219-1|AAH65219.2| 236|Homo sapiens Notch homolog 2 (Drosophila) N-terminal like protein. Length = 236 Score = 56.0 bits (129), Expect = 8e-08 Identities = 35/99 (35%), Positives = 44/99 (44%), Gaps = 6/99 (6%) Frame = +2 Query: 203 ENVQNCFTCAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCD-RIGESC---RPGLCGP 370 E Q+ C N C N G C C CA GF G +C C RP L G Sbjct: 21 EYCQHRDPCEKNRCQNGGTCVAQAMLGKATCRCASGFTGEDCQYSTSHPCFVSRPCLNG- 79 Query: 371 GKC-MNTADSYKCACPVTYTGKNCE-VKQLIEYPAFTGS 481 G C M + D+Y+C C V +TGK C+ + +P GS Sbjct: 80 GTCHMLSRDTYECTCQVGFTGKECQWTDACLSHPCANGS 118 Score = 49.6 bits (113), Expect = 7e-06 Identities = 24/74 (32%), Positives = 33/74 (44%), Gaps = 2/74 (2%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCR-PGLCGPGK-CMNTADSY 400 C + C N C + + C C GF G C+ C PG C G C+N SY Sbjct: 109 CLSHPCANGSTCTTVANQ--FSCKCLTGFTGQKCETDVNECDIPGHCQHGGICLNLPGSY 166 Query: 401 KCACPVTYTGKNCE 442 +C C +TG+ C+ Sbjct: 167 QCQCLQGFTGQYCD 180 Score = 42.7 bits (96), Expect = 8e-04 Identities = 21/62 (33%), Positives = 27/62 (43%), Gaps = 2/62 (3%) Frame = +2 Query: 233 PNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLC-GPGKCMNTAD-SYKC 406 P C + G+C Y C C GF G CD + C P C G C T D +++C Sbjct: 150 PGHCQHGGICLNL--PGSYQCQCLQGFTGQYCDSLYVPCAPSPCVNGGTCRQTGDFTFEC 207 Query: 407 AC 412 C Sbjct: 208 NC 209 >BC019835-1|AAH19835.1| 236|Homo sapiens Notch homolog 2 N-terminal like protein protein. Length = 236 Score = 56.0 bits (129), Expect = 8e-08 Identities = 35/99 (35%), Positives = 44/99 (44%), Gaps = 6/99 (6%) Frame = +2 Query: 203 ENVQNCFTCAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCD-RIGESC---RPGLCGP 370 E Q+ C N C N G C C CA GF G +C C RP L G Sbjct: 21 EYCQHRDPCEKNRCQNGGTCVAQAMLGKATCRCASGFTGEDCQYSTSHPCFVSRPCLNG- 79 Query: 371 GKC-MNTADSYKCACPVTYTGKNCE-VKQLIEYPAFTGS 481 G C M + D+Y+C C V +TGK C+ + +P GS Sbjct: 80 GTCHMLSRDTYECTCQVGFTGKECQWTDACLSHPCANGS 118 Score = 49.6 bits (113), Expect = 7e-06 Identities = 24/74 (32%), Positives = 33/74 (44%), Gaps = 2/74 (2%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCR-PGLCGPGK-CMNTADSY 400 C + C N C + + C C GF G C+ C PG C G C+N SY Sbjct: 109 CLSHPCANGSTCTTVANQ--FSCKCLTGFTGQKCETDVNECDIPGHCQHGGICLNLPGSY 166 Query: 401 KCACPVTYTGKNCE 442 +C C +TG+ C+ Sbjct: 167 QCQCLQGFTGQYCD 180 Score = 42.7 bits (96), Expect = 8e-04 Identities = 21/62 (33%), Positives = 27/62 (43%), Gaps = 2/62 (3%) Frame = +2 Query: 233 PNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLC-GPGKCMNTAD-SYKC 406 P C + G+C Y C C GF G CD + C P C G C T D +++C Sbjct: 150 PGHCQHGGICLNL--PGSYQCQCLQGFTGQYCDSLYVPCAPSPCVNGGTCRQTGDFTFEC 207 Query: 407 AC 412 C Sbjct: 208 NC 209 >BC010154-1|AAH10154.3| 236|Homo sapiens Notch homolog 2 (Drosophila) N-terminal like protein. Length = 236 Score = 56.0 bits (129), Expect = 8e-08 Identities = 35/99 (35%), Positives = 44/99 (44%), Gaps = 6/99 (6%) Frame = +2 Query: 203 ENVQNCFTCAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCD-RIGESC---RPGLCGP 370 E Q+ C N C N G C C CA GF G +C C RP L G Sbjct: 21 EYCQHRDPCEKNRCQNGGTCVAQAMLGKATCRCASGFTGEDCQYSTSHPCFVSRPCLNG- 79 Query: 371 GKC-MNTADSYKCACPVTYTGKNCE-VKQLIEYPAFTGS 481 G C M + D+Y+C C V +TGK C+ + +P GS Sbjct: 80 GTCHMLSRDTYECTCQVGFTGKECQWTDACLSHPCANGS 118 Score = 50.0 bits (114), Expect = 5e-06 Identities = 24/74 (32%), Positives = 33/74 (44%), Gaps = 2/74 (2%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCR-PGLCGPG-KCMNTADSY 400 C + C N C + + C C GF G C+ C PG C G C+N SY Sbjct: 109 CLSHPCANGSTCTTVANQ--FSCKCLTGFTGQKCETDVNECDIPGHCQHGGTCLNLPGSY 166 Query: 401 KCACPVTYTGKNCE 442 +C C +TG+ C+ Sbjct: 167 QCQCLQGFTGQYCD 180 Score = 41.5 bits (93), Expect = 0.002 Identities = 21/62 (33%), Positives = 26/62 (41%), Gaps = 2/62 (3%) Frame = +2 Query: 233 PNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLC-GPGKCMNTAD-SYKC 406 P C + G C Y C C GF G CD + C P C G C T D +++C Sbjct: 150 PGHCQHGGTCLNL--PGSYQCQCLQGFTGQYCDSLYVPCAPSPCVNGGTCRQTGDFTFEC 207 Query: 407 AC 412 C Sbjct: 208 NC 209 >AY165865-1|AAO18147.1| 2809|Homo sapiens fibrillin-3 short form precursor transcript variant 3 protein. Length = 2809 Score = 56.0 bits (129), Expect = 8e-08 Identities = 30/67 (44%), Positives = 36/67 (53%), Gaps = 5/67 (7%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHG-YVCLCAPGF----GGNNCDRIGESCRPGLCGPGKCMNTA 391 CA + NGVC L E G + CLC PGF GG+ C I E PG+C G C NT Sbjct: 535 CATSTMCVNGVC---LNEDGSFSCLCKPGFLLAPGGHYCMDIDECQTPGICVNGHCTNTE 591 Query: 392 DSYKCAC 412 S++C C Sbjct: 592 GSFRCQC 598 Score = 49.6 bits (113), Expect = 7e-06 Identities = 32/103 (31%), Positives = 48/103 (46%), Gaps = 10/103 (9%) Frame = +2 Query: 203 ENVQNCFTCAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNN----CDRIGE-SCRPGLCG 367 E++ C P LC G C T + C C PG+ + C+ I E S +CG Sbjct: 1562 EDIDECQEL-PGLC-QGGDCVN--TFGSFQCECPPGYHLSEHTRICEDIDECSTHSSICG 1617 Query: 368 PGKCMNTADSYKCACPVTYT----GKNC-EVKQLIEYPAFTGS 481 PG C NT +Y C CP Y G NC ++++ + + + G+ Sbjct: 1618 PGTCYNTLGNYTCVCPAEYLQVNGGNNCMDMRKSVCFRHYNGT 1660 Score = 49.2 bits (112), Expect = 9e-06 Identities = 35/98 (35%), Positives = 44/98 (44%), Gaps = 12/98 (12%) Frame = +2 Query: 185 ALALEKENVQNCFTC--APNLCLNNGVCQEALTEHGYVCLCAPGFGGN-----NCDRIGE 343 AL ++ N + C +P+LC G C T + C C PG+ NC + E Sbjct: 1018 ALDAQERNCTDIDECRISPDLC-GQGTCVN--TPGSFECECFPGYESGFMLMKNCMDVDE 1074 Query: 344 SCR-PGLCGPGKCMNTADSYKCACP----VTYTGKNCE 442 R P LC G C NT SYKC CP +T G CE Sbjct: 1075 CARDPLLCRGGTCTNTDGSYKCQCPPGHELTAKGTACE 1112 Score = 48.0 bits (109), Expect = 2e-05 Identities = 28/66 (42%), Positives = 34/66 (51%), Gaps = 6/66 (9%) Frame = +2 Query: 233 PNLCLNNGVCQEALTEHGYVCLCAPGFG----GNNCDRIGESCR--PGLCGPGKCMNTAD 394 P LC +G C+ T + C CA GF NC I E CR P LCG G C+NT Sbjct: 994 PGLC-THGTCRN--TVGSFHCACAGGFALDAQERNCTDIDE-CRISPDLCGQGTCVNTPG 1049 Query: 395 SYKCAC 412 S++C C Sbjct: 1050 SFECEC 1055 Score = 44.8 bits (101), Expect = 2e-04 Identities = 21/44 (47%), Positives = 27/44 (61%), Gaps = 5/44 (11%) Frame = +2 Query: 299 CAPGFG---GNNCDRIGESCR--PGLCGPGKCMNTADSYKCACP 415 CA GF G CD + E C PG+C G+C+NTA S++C CP Sbjct: 855 CARGFARMTGVTCDDVNE-CESFPGVCPNGRCVNTAGSFRCECP 897 Score = 44.8 bits (101), Expect = 2e-04 Identities = 28/73 (38%), Positives = 35/73 (47%), Gaps = 5/73 (6%) Frame = +2 Query: 212 QNCFTCAP-NLCLNNGVCQEALTEHGYVCLCAPGF----GGNNCDRIGESCRPGLCGPGK 376 Q+ CA NLC G C+ + C+C G+ GG NC I E P C G Sbjct: 1403 QDVDECAQGNLCAF-GSCENL--PGMFRCICNGGYELDRGGGNCTDINECADPVNCINGV 1459 Query: 377 CMNTADSYKCACP 415 C+NT SY C+CP Sbjct: 1460 CINTPGSYLCSCP 1472 Score = 44.0 bits (99), Expect = 3e-04 Identities = 26/64 (40%), Positives = 32/64 (50%), Gaps = 4/64 (6%) Frame = +2 Query: 233 PNLCLNNGVCQEALTEHGYVCLCAPGFGGNN----CDRIGESCRPGLCGPGKCMNTADSY 400 PN+C ++G C + TE Y+CLC GF + C I E C CG G C N SY Sbjct: 1813 PNVC-SHGDCMD--TEGSYMCLCHRGFQASADQTLCMDIDE-CDRQPCGNGTCKNIIGSY 1868 Query: 401 KCAC 412 C C Sbjct: 1869 NCLC 1872 Score = 44.0 bits (99), Expect = 3e-04 Identities = 27/73 (36%), Positives = 36/73 (49%), Gaps = 3/73 (4%) Frame = +2 Query: 206 NVQNCFTCAPNLCLNNGVCQEALTEHGYVCLCAPGFG--GNNCDRIGE-SCRPGLCGPGK 376 + C + A CL G CQ E + C+C PGF ++C I E S P LC G Sbjct: 1929 DTNECLSLA-GTCLP-GTCQNL--EGSFRCICPPGFQVQSDHCIDIDECSEEPNLCLFGT 1984 Query: 377 CMNTADSYKCACP 415 C N+ S++C CP Sbjct: 1985 CTNSPGSFQCLCP 1997 Score = 43.6 bits (98), Expect = 4e-04 Identities = 27/77 (35%), Positives = 37/77 (48%), Gaps = 7/77 (9%) Frame = +2 Query: 203 ENVQNCFTCA--PNLCLNNGVCQEALTEHGYVCLCAPGFG----GNNCDRIGE-SCRPGL 361 +N + CA P LC G C T+ Y C C PG G C+ I E S GL Sbjct: 1067 KNCMDVDECARDPLLC-RGGTCTN--TDGSYKCQCPPGHELTAKGTACEDIDECSLSDGL 1123 Query: 362 CGPGKCMNTADSYKCAC 412 C G+C+N +++C+C Sbjct: 1124 CPHGQCVNVIGAFQCSC 1140 Score = 42.7 bits (96), Expect = 8e-04 Identities = 24/83 (28%), Positives = 37/83 (44%), Gaps = 5/83 (6%) Frame = +2 Query: 182 MALALEKENVQNCFTCAPNLCLNNGVCQEALTEHGYVCLCAPGF----GGNNCDRIGESC 349 + + + ++ C P +C N GVC+ Y C+C G+ G +C + E Sbjct: 674 LGITTDGRDINEC-ALDPEVCAN-GVCENL--RGSYRCVCNLGYEAGASGKDCTDVDECA 729 Query: 350 RPGL-CGPGKCMNTADSYKCACP 415 L C G C N+ SY C+CP Sbjct: 730 LNSLLCDNGWCQNSPGSYSCSCP 752 Score = 42.3 bits (95), Expect = 0.001 Identities = 26/71 (36%), Positives = 31/71 (43%), Gaps = 4/71 (5%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGN---NCDRIGE-SCRPGLCGPGKCMNTAD 394 C+ G C + G+ C CA GF C+ I E S P LC +C NT Sbjct: 2130 CSVGHPCGQGTCTNVIG--GFECACADGFEPGLMMTCEDIDECSLNPLLCA-FRCHNTEG 2186 Query: 395 SYKCACPVTYT 427 SY C CP YT Sbjct: 2187 SYLCTCPAGYT 2197 Score = 41.5 bits (93), Expect = 0.002 Identities = 27/72 (37%), Positives = 36/72 (50%), Gaps = 9/72 (12%) Frame = +2 Query: 251 NGVCQEALTEHGYVCLCAPGF-GGNNCDRIG-ESCRP---GLCGPGKCMNTADSYKCAC- 412 NG C+ + Y CLC PGF +N D + + C +C G C+NTA S+ C C Sbjct: 1858 NGTCKNIIGS--YNCLCFPGFVVTHNGDCVDFDECTTLVGQVCRFGHCLNTAGSFHCLCQ 1915 Query: 413 ---PVTYTGKNC 439 +T GKNC Sbjct: 1916 DGFELTADGKNC 1927 Score = 40.3 bits (90), Expect = 0.004 Identities = 25/71 (35%), Positives = 29/71 (40%), Gaps = 5/71 (7%) Frame = +2 Query: 218 CFTCAPNLCLNNGVCQEALTEHGYVCLCAPGF----GGNNCDRIGESCR-PGLCGPGKCM 382 C T +C G C T + CLC GF G NC E G C PG C Sbjct: 1890 CTTLVGQVC-RFGHCLN--TAGSFHCLCQDGFELTADGKNCVDTNECLSLAGTCLPGTCQ 1946 Query: 383 NTADSYKCACP 415 N S++C CP Sbjct: 1947 NLEGSFRCICP 1957 Score = 40.3 bits (90), Expect = 0.004 Identities = 26/75 (34%), Positives = 33/75 (44%), Gaps = 4/75 (5%) Frame = +2 Query: 200 KENVQNCFTCAPNLCLNNGVCQEALTEHGYVCLCAPG----FGGNNCDRIGESCRPGLCG 367 +E+V C P +C NGVC T+ + C C G F G NC E CG Sbjct: 2082 REDVNECAE-NPGVC-TNGVCVN--TDGSFRCECPFGYSLDFTGINCVDTDECSVGHPCG 2137 Query: 368 PGKCMNTADSYKCAC 412 G C N ++CAC Sbjct: 2138 QGTCTNVIGGFECAC 2152 Score = 39.9 bits (89), Expect = 0.006 Identities = 26/67 (38%), Positives = 29/67 (43%), Gaps = 5/67 (7%) Frame = +2 Query: 227 CAPN-LCLNNGVCQEALTEHGYVCLCAPGF----GGNNCDRIGESCRPGLCGPGKCMNTA 391 CA N L +NG CQ + Y C C PGF C + E C C G C N A Sbjct: 728 CALNSLLCDNGWCQNS--PGSYSCSCPPGFHFWQDTEICKDVDE-CLSSPCVSGVCRNLA 784 Query: 392 DSYKCAC 412 SY C C Sbjct: 785 GSYTCKC 791 Score = 39.9 bits (89), Expect = 0.006 Identities = 18/48 (37%), Positives = 25/48 (52%), Gaps = 6/48 (12%) Frame = +2 Query: 287 YVCLCAPGF-----GGNNCDRIGES-CRPGLCGPGKCMNTADSYKCAC 412 + C+C PG G C E +P LC G+C+NTA S++C C Sbjct: 2232 FACVCPPGMRPLPGSGEGCTDDNECHAQPDLCVNGRCVNTAGSFRCDC 2279 Score = 39.5 bits (88), Expect = 0.007 Identities = 27/80 (33%), Positives = 33/80 (41%), Gaps = 9/80 (11%) Frame = +2 Query: 227 CAPNLCL-NNGVCQEALTEHGYVCLCAPGFGGNN----CDRIGESCRPGLCGPGKCMNTA 391 CA N+ L +NG C A GY C C GF C + E + LC G C N Sbjct: 1366 CAENVDLCDNGQCLNA--PGGYRCECEMGFDPTEDHRACQDVDECAQGNLCAFGSCENLP 1423 Query: 392 DSYKCACPVTYT----GKNC 439 ++C C Y G NC Sbjct: 1424 GMFRCICNGGYELDRGGGNC 1443 Score = 39.5 bits (88), Expect = 0.007 Identities = 22/69 (31%), Positives = 30/69 (43%), Gaps = 4/69 (5%) Frame = +2 Query: 233 PNLCLNNGVCQEALTEHGYVCLCAPGF----GGNNCDRIGESCRPGLCGPGKCMNTADSY 400 P C +G C T + C C GF G+ C+ + E P C G C N Y Sbjct: 2493 PGPCGAHGHCHN--TPGSFRCECHQGFTLVSSGHGCEDVNECDGPHRCQHG-CQNQLGGY 2549 Query: 401 KCACPVTYT 427 +C+CP +T Sbjct: 2550 RCSCPQGFT 2558 Score = 38.3 bits (85), Expect = 0.017 Identities = 22/60 (36%), Positives = 28/60 (46%), Gaps = 9/60 (15%) Frame = +2 Query: 287 YVCLCAPGFGGNN----CDRIGESC-RPGLCGPGKCMNTADSYKCACPVTY----TGKNC 439 Y C C PGF C + E GLC G+C+NT S++C C + GKNC Sbjct: 470 YHCRCYPGFQATPTRQACVDVDECIVSGGLCHLGRCVNTEGSFQCVCNAGFELSPDGKNC 529 Score = 38.3 bits (85), Expect = 0.017 Identities = 23/72 (31%), Positives = 33/72 (45%), Gaps = 5/72 (6%) Frame = +2 Query: 239 LCLNNGVCQ-EALTEHGYVCLCAPGFGGNNCDRIGESCRPGLCGPGKCMNTADSYKCACP 415 LC G + L G+ + P + + E+ PG+C G C+NT S++C CP Sbjct: 2055 LCPQEGSAAFQELCPFGHGAVPGPDDSREDVNECAEN--PGVCTNGVCVNTDGSFRCECP 2112 Query: 416 VTY----TGKNC 439 Y TG NC Sbjct: 2113 FGYSLDFTGINC 2124 Score = 37.1 bits (82), Expect = 0.039 Identities = 25/76 (32%), Positives = 33/76 (43%), Gaps = 5/76 (6%) Frame = +2 Query: 203 ENVQNCFTCAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNN----CDRIGE-SCRPGLCG 367 E+V C P+ C + CQ L GY C C GF ++ C E + P CG Sbjct: 2527 EDVNECD--GPHRCQHG--CQNQLG--GYRCSCPQGFTQHSQWAQCVDENECALSPPTCG 2580 Query: 368 PGKCMNTADSYKCACP 415 C NT ++C CP Sbjct: 2581 SASCRNTLGGFRCVCP 2596 Score = 36.7 bits (81), Expect = 0.052 Identities = 27/84 (32%), Positives = 35/84 (41%), Gaps = 5/84 (5%) Frame = +2 Query: 176 NIMALALEKENVQNCFTCAPNLCLNNGVCQEALTEHGYVCLCAPGFG---GNNCDRIGES 346 N ++ L E+V C + + C N C Y C C G+ G C E Sbjct: 1753 NYNSILLACEDVDECGS-RESPCQQNADCINI--PGSYRCKCTRGYKLSPGGACVGRNE- 1808 Query: 347 CR--PGLCGPGKCMNTADSYKCAC 412 CR P +C G CM+T SY C C Sbjct: 1809 CREIPNVCSHGDCMDTEGSYMCLC 1832 Score = 35.9 bits (79), Expect = 0.090 Identities = 17/50 (34%), Positives = 22/50 (44%), Gaps = 4/50 (8%) Frame = +2 Query: 275 TEHGYVCLCAPGF----GGNNCDRIGESCRPGLCGPGKCMNTADSYKCAC 412 TE + C+C GF G NC E +C G C+N S+ C C Sbjct: 508 TEGSFQCVCNAGFELSPDGKNCVDHNECATSTMCVNGVCLNEDGSFSCLC 557 Score = 35.9 bits (79), Expect = 0.090 Identities = 16/49 (32%), Positives = 23/49 (46%), Gaps = 3/49 (6%) Frame = +2 Query: 287 YVCLCAPGFGGNN--CDRIGESCRP-GLCGPGKCMNTADSYKCACPVTY 424 Y C C GF G+ C+ E LC G+C+N Y+C C + + Sbjct: 1345 YRCTCRQGFAGDGFFCEDRDECAENVDLCDNGQCLNAPGGYRCECEMGF 1393 Score = 35.5 bits (78), Expect = 0.12 Identities = 19/57 (33%), Positives = 26/57 (45%), Gaps = 6/57 (10%) Frame = +2 Query: 287 YVCLCAPGFGGNNCDRIGESCR--PGLCGPGKCMNTADSYKCACPVTY----TGKNC 439 + LC+ G G R C P +C G C N SY+C C + Y +GK+C Sbjct: 666 FQALCSSGLGITTDGRDINECALDPEVCANGVCENLRGSYRCVCNLGYEAGASGKDC 722 Score = 35.1 bits (77), Expect = 0.16 Identities = 16/40 (40%), Positives = 20/40 (50%), Gaps = 2/40 (5%) Frame = +2 Query: 305 PGFGGNNCDRIGESCR--PGLCGPGKCMNTADSYKCACPV 418 P C + E C+ PGLC G C+N S+ C CPV Sbjct: 238 PNIHTGACQDVDE-CQAVPGLCQGGSCVNMVGSFHCRCPV 276 Score = 35.1 bits (77), Expect = 0.16 Identities = 18/49 (36%), Positives = 24/49 (48%), Gaps = 2/49 (4%) Frame = +2 Query: 287 YVCLCAPGFGGNNCDRIGESCR--PGLCGPGKCMNTADSYKCACPVTYT 427 Y LC G G R + CR LC G+C+N+ S++C C YT Sbjct: 2347 YRKLCPHGSGYTAEGRDVDECRMLAHLCAHGECINSLGSFRCHCQAGYT 2395 Score = 34.3 bits (75), Expect = 0.27 Identities = 25/83 (30%), Positives = 36/83 (43%), Gaps = 7/83 (8%) Frame = +2 Query: 233 PNLCLNNGVCQEALTEHGYVCLCAPGF----GGNNCDRIGESCRPG--LCGP-GKCMNTA 391 P++CL+ G C+ T+ +VC C G+ G C + E C G C C+N Sbjct: 1246 PHICLH-GDCEN--TKGSFVCHCQLGYMVRKGATGCSDVDE-CEVGGHNCDSHASCLNIP 1301 Query: 392 DSYKCACPVTYTGKNCEVKQLIE 460 S+ C C + G E L E Sbjct: 1302 GSFSCRCLPGWVGDGFECHDLDE 1324 Score = 34.3 bits (75), Expect = 0.27 Identities = 17/52 (32%), Positives = 25/52 (48%), Gaps = 4/52 (7%) Frame = +2 Query: 287 YVCLCAPGFGGNN--CDRIGESC-RPGLCGP-GKCMNTADSYKCACPVTYTG 430 + C C PG+ G+ C + E + C P G C+N SY+C C + G Sbjct: 1304 FSCRCLPGWVGDGFECHDLDECVSQEHRCSPRGDCLNVPGSYRCTCRQGFAG 1355 Score = 33.9 bits (74), Expect = 0.36 Identities = 22/62 (35%), Positives = 27/62 (43%), Gaps = 3/62 (4%) Frame = +2 Query: 236 NLCLNNGVCQEALTEHGYVCLCAPGFGGN---NCDRIGESCRPGLCGPGKCMNTADSYKC 406 NLCLN G C T Y C C G+ + C + E C C G C+N +Y C Sbjct: 417 NLCLN-GRCLP--TPSSYRCECNVGYTQDVRGECIDVDE-CTSSPCHHGDCVNIPGTYHC 472 Query: 407 AC 412 C Sbjct: 473 RC 474 Score = 33.5 bits (73), Expect = 0.48 Identities = 22/69 (31%), Positives = 29/69 (42%), Gaps = 5/69 (7%) Frame = +2 Query: 233 PNLCLNNGVCQEALTEHGYVCLCAPGFGGN----NCDRIGE-SCRPGLCGPGKCMNTADS 397 P +C + G C G+ CLC GF C + E P +C G C NT S Sbjct: 1204 PRVC-DQGHCTNM--PGGHRCLCYDGFMATPDMRTCVDVDECDLNPHICLHGDCENTKGS 1260 Query: 398 YKCACPVTY 424 + C C + Y Sbjct: 1261 FVCHCQLGY 1269 Score = 32.3 bits (70), Expect = 1.1 Identities = 12/23 (52%), Positives = 15/23 (65%) Frame = +2 Query: 359 LCGPGKCMNTADSYKCACPVTYT 427 LC G+C+ T SY+C C V YT Sbjct: 418 LCLNGRCLPTPSSYRCECNVGYT 440 Score = 31.5 bits (68), Expect = 1.9 Identities = 28/83 (33%), Positives = 34/83 (40%), Gaps = 12/83 (14%) Frame = +2 Query: 233 PNLCLNNGVCQEALTEHGYVCLCAPGF----GGNNC-DRIGESC----RPGLCGPGKCMN 385 PNLCL G C + + CLC PGF G+ C D C G C K N Sbjct: 1977 PNLCLF-GTCTNS--PGSFQCLCPPGFVLSDNGHRCFDTRQSFCFTRFEAGKCSVPKAFN 2033 Query: 386 TADSYKCAC---PVTYTGKNCEV 445 T + +C C P G CE+ Sbjct: 2034 TTKT-RCCCSKRPGEGWGDPCEL 2055 Score = 31.1 bits (67), Expect = 2.6 Identities = 12/32 (37%), Positives = 17/32 (53%) Frame = +2 Query: 329 DRIGESCRPGLCGPGKCMNTADSYKCACPVTY 424 D GE P +C G C+N S++C CP + Sbjct: 1723 DECGEI--PAICANGICINQIGSFRCECPAGF 1752 Score = 30.7 bits (66), Expect = 3.4 Identities = 21/70 (30%), Positives = 30/70 (42%), Gaps = 6/70 (8%) Frame = +2 Query: 233 PNLCLNNGVCQEALTEHGYVCLCAPGFGGNN----CDRIGE-SCRPGLCGPGK-CMNTAD 394 P +C N G+C + + C C GF N+ C+ + E R C C+N Sbjct: 1729 PAICAN-GICINQIGS--FRCECPAGFNYNSILLACEDVDECGSRESPCQQNADCINIPG 1785 Query: 395 SYKCACPVTY 424 SY+C C Y Sbjct: 1786 SYRCKCTRGY 1795 Score = 30.7 bits (66), Expect = 3.4 Identities = 22/76 (28%), Positives = 31/76 (40%), Gaps = 5/76 (6%) Frame = +2 Query: 212 QNCFTCAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNN----CDRIGESC-RPGLCGPGK 376 +N +P C + C+ L G+ C+C GF + C + E R G C Sbjct: 2569 ENECALSPPTC-GSASCRNTLG--GFRCVCPSGFDFDQALGGCQDVDECAGRRGPCSYS- 2624 Query: 377 CMNTADSYKCACPVTY 424 C NT + C CP Y Sbjct: 2625 CANTPGGFLCGCPQGY 2640 Score = 29.5 bits (63), Expect = 7.8 Identities = 25/81 (30%), Positives = 36/81 (44%), Gaps = 6/81 (7%) Frame = +2 Query: 203 ENVQNCFTCAPNLCLNNGVCQEALTEHGYVCLCAPGFGGN----NCDRIGESCRP--GLC 364 E++ C + + LC +G C + + C C GF C I E CR G C Sbjct: 1112 EDIDEC-SLSDGLC-PHGQCVNVIG--AFQCSCHAGFQSTPDRQGCVDINE-CRVQNGGC 1166 Query: 365 GPGKCMNTADSYKCACPVTYT 427 C+NT SY+C+C Y+ Sbjct: 1167 DV-HCINTEGSYRCSCGQGYS 1186 >AY165864-1|AAO18146.1| 2809|Homo sapiens fibrillin-3 short form precursor transcript variant 2 protein. Length = 2809 Score = 56.0 bits (129), Expect = 8e-08 Identities = 30/67 (44%), Positives = 36/67 (53%), Gaps = 5/67 (7%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHG-YVCLCAPGF----GGNNCDRIGESCRPGLCGPGKCMNTA 391 CA + NGVC L E G + CLC PGF GG+ C I E PG+C G C NT Sbjct: 535 CATSTMCVNGVC---LNEDGSFSCLCKPGFLLAPGGHYCMDIDECQTPGICVNGHCTNTE 591 Query: 392 DSYKCAC 412 S++C C Sbjct: 592 GSFRCQC 598 Score = 49.6 bits (113), Expect = 7e-06 Identities = 32/103 (31%), Positives = 48/103 (46%), Gaps = 10/103 (9%) Frame = +2 Query: 203 ENVQNCFTCAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNN----CDRIGE-SCRPGLCG 367 E++ C P LC G C T + C C PG+ + C+ I E S +CG Sbjct: 1562 EDIDECQEL-PGLC-QGGDCVN--TFGSFQCECPPGYHLSEHTRICEDIDECSTHSSICG 1617 Query: 368 PGKCMNTADSYKCACPVTYT----GKNC-EVKQLIEYPAFTGS 481 PG C NT +Y C CP Y G NC ++++ + + + G+ Sbjct: 1618 PGTCYNTLGNYTCVCPAEYLQVNGGNNCMDMRKSVCFRHYNGT 1660 Score = 49.2 bits (112), Expect = 9e-06 Identities = 35/98 (35%), Positives = 44/98 (44%), Gaps = 12/98 (12%) Frame = +2 Query: 185 ALALEKENVQNCFTC--APNLCLNNGVCQEALTEHGYVCLCAPGFGGN-----NCDRIGE 343 AL ++ N + C +P+LC G C T + C C PG+ NC + E Sbjct: 1018 ALDAQERNCTDIDECRISPDLC-GQGTCVN--TPGSFECECFPGYESGFMLMKNCMDVDE 1074 Query: 344 SCR-PGLCGPGKCMNTADSYKCACP----VTYTGKNCE 442 R P LC G C NT SYKC CP +T G CE Sbjct: 1075 CARDPLLCRGGTCTNTDGSYKCQCPPGHELTAKGTACE 1112 Score = 48.0 bits (109), Expect = 2e-05 Identities = 28/66 (42%), Positives = 34/66 (51%), Gaps = 6/66 (9%) Frame = +2 Query: 233 PNLCLNNGVCQEALTEHGYVCLCAPGFG----GNNCDRIGESCR--PGLCGPGKCMNTAD 394 P LC +G C+ T + C CA GF NC I E CR P LCG G C+NT Sbjct: 994 PGLC-THGTCRN--TVGSFHCACAGGFALDAQERNCTDIDE-CRISPDLCGQGTCVNTPG 1049 Query: 395 SYKCAC 412 S++C C Sbjct: 1050 SFECEC 1055 Score = 44.8 bits (101), Expect = 2e-04 Identities = 21/44 (47%), Positives = 27/44 (61%), Gaps = 5/44 (11%) Frame = +2 Query: 299 CAPGFG---GNNCDRIGESCR--PGLCGPGKCMNTADSYKCACP 415 CA GF G CD + E C PG+C G+C+NTA S++C CP Sbjct: 855 CARGFARMTGVTCDDVNE-CESFPGVCPNGRCVNTAGSFRCECP 897 Score = 44.8 bits (101), Expect = 2e-04 Identities = 28/73 (38%), Positives = 35/73 (47%), Gaps = 5/73 (6%) Frame = +2 Query: 212 QNCFTCAP-NLCLNNGVCQEALTEHGYVCLCAPGF----GGNNCDRIGESCRPGLCGPGK 376 Q+ CA NLC G C+ + C+C G+ GG NC I E P C G Sbjct: 1403 QDVDECAQGNLCAF-GSCENL--PGMFRCICNGGYELDRGGGNCTDINECADPVNCINGV 1459 Query: 377 CMNTADSYKCACP 415 C+NT SY C+CP Sbjct: 1460 CINTPGSYLCSCP 1472 Score = 44.0 bits (99), Expect = 3e-04 Identities = 26/64 (40%), Positives = 32/64 (50%), Gaps = 4/64 (6%) Frame = +2 Query: 233 PNLCLNNGVCQEALTEHGYVCLCAPGFGGNN----CDRIGESCRPGLCGPGKCMNTADSY 400 PN+C ++G C + TE Y+CLC GF + C I E C CG G C N SY Sbjct: 1813 PNVC-SHGDCMD--TEGSYMCLCHRGFQASADQTLCMDIDE-CDRQPCGNGTCKNIIGSY 1868 Query: 401 KCAC 412 C C Sbjct: 1869 NCLC 1872 Score = 44.0 bits (99), Expect = 3e-04 Identities = 27/73 (36%), Positives = 36/73 (49%), Gaps = 3/73 (4%) Frame = +2 Query: 206 NVQNCFTCAPNLCLNNGVCQEALTEHGYVCLCAPGFG--GNNCDRIGE-SCRPGLCGPGK 376 + C + A CL G CQ E + C+C PGF ++C I E S P LC G Sbjct: 1929 DTNECLSLA-GTCLP-GTCQNL--EGSFRCICPPGFQVQSDHCIDIDECSEEPNLCLFGT 1984 Query: 377 CMNTADSYKCACP 415 C N+ S++C CP Sbjct: 1985 CTNSPGSFQCLCP 1997 Score = 43.6 bits (98), Expect = 4e-04 Identities = 27/77 (35%), Positives = 37/77 (48%), Gaps = 7/77 (9%) Frame = +2 Query: 203 ENVQNCFTCA--PNLCLNNGVCQEALTEHGYVCLCAPGFG----GNNCDRIGE-SCRPGL 361 +N + CA P LC G C T+ Y C C PG G C+ I E S GL Sbjct: 1067 KNCMDVDECARDPLLC-RGGTCTN--TDGSYKCQCPPGHELTAKGTACEDIDECSLSDGL 1123 Query: 362 CGPGKCMNTADSYKCAC 412 C G+C+N +++C+C Sbjct: 1124 CPHGQCVNVIGAFQCSC 1140 Score = 42.7 bits (96), Expect = 8e-04 Identities = 24/83 (28%), Positives = 37/83 (44%), Gaps = 5/83 (6%) Frame = +2 Query: 182 MALALEKENVQNCFTCAPNLCLNNGVCQEALTEHGYVCLCAPGF----GGNNCDRIGESC 349 + + + ++ C P +C N GVC+ Y C+C G+ G +C + E Sbjct: 674 LGITTDGRDINEC-ALDPEVCAN-GVCENL--RGSYRCVCNLGYEAGASGKDCTDVDECA 729 Query: 350 RPGL-CGPGKCMNTADSYKCACP 415 L C G C N+ SY C+CP Sbjct: 730 LNSLLCDNGWCQNSPGSYSCSCP 752 Score = 42.3 bits (95), Expect = 0.001 Identities = 26/71 (36%), Positives = 31/71 (43%), Gaps = 4/71 (5%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGN---NCDRIGE-SCRPGLCGPGKCMNTAD 394 C+ G C + G+ C CA GF C+ I E S P LC +C NT Sbjct: 2130 CSVGHPCGQGTCTNVIG--GFECACADGFEPGLMMTCEDIDECSLNPLLCA-FRCHNTEG 2186 Query: 395 SYKCACPVTYT 427 SY C CP YT Sbjct: 2187 SYLCTCPAGYT 2197 Score = 41.5 bits (93), Expect = 0.002 Identities = 27/72 (37%), Positives = 36/72 (50%), Gaps = 9/72 (12%) Frame = +2 Query: 251 NGVCQEALTEHGYVCLCAPGF-GGNNCDRIG-ESCRP---GLCGPGKCMNTADSYKCAC- 412 NG C+ + Y CLC PGF +N D + + C +C G C+NTA S+ C C Sbjct: 1858 NGTCKNIIGS--YNCLCFPGFVVTHNGDCVDFDECTTLVGQVCRFGHCLNTAGSFHCLCQ 1915 Query: 413 ---PVTYTGKNC 439 +T GKNC Sbjct: 1916 DGFELTADGKNC 1927 Score = 40.3 bits (90), Expect = 0.004 Identities = 25/71 (35%), Positives = 29/71 (40%), Gaps = 5/71 (7%) Frame = +2 Query: 218 CFTCAPNLCLNNGVCQEALTEHGYVCLCAPGF----GGNNCDRIGESCR-PGLCGPGKCM 382 C T +C G C T + CLC GF G NC E G C PG C Sbjct: 1890 CTTLVGQVC-RFGHCLN--TAGSFHCLCQDGFELTADGKNCVDTNECLSLAGTCLPGTCQ 1946 Query: 383 NTADSYKCACP 415 N S++C CP Sbjct: 1947 NLEGSFRCICP 1957 Score = 40.3 bits (90), Expect = 0.004 Identities = 26/75 (34%), Positives = 33/75 (44%), Gaps = 4/75 (5%) Frame = +2 Query: 200 KENVQNCFTCAPNLCLNNGVCQEALTEHGYVCLCAPG----FGGNNCDRIGESCRPGLCG 367 +E+V C P +C NGVC T+ + C C G F G NC E CG Sbjct: 2082 REDVNECAE-NPGVC-TNGVCVN--TDGSFRCECPFGYSLDFTGINCVDTDECSVGHPCG 2137 Query: 368 PGKCMNTADSYKCAC 412 G C N ++CAC Sbjct: 2138 QGTCTNVIGGFECAC 2152 Score = 39.9 bits (89), Expect = 0.006 Identities = 26/67 (38%), Positives = 29/67 (43%), Gaps = 5/67 (7%) Frame = +2 Query: 227 CAPN-LCLNNGVCQEALTEHGYVCLCAPGF----GGNNCDRIGESCRPGLCGPGKCMNTA 391 CA N L +NG CQ + Y C C PGF C + E C C G C N A Sbjct: 728 CALNSLLCDNGWCQNS--PGSYSCSCPPGFHFWQDTEICKDVDE-CLSSPCVSGVCRNLA 784 Query: 392 DSYKCAC 412 SY C C Sbjct: 785 GSYTCKC 791 Score = 39.9 bits (89), Expect = 0.006 Identities = 18/48 (37%), Positives = 25/48 (52%), Gaps = 6/48 (12%) Frame = +2 Query: 287 YVCLCAPGF-----GGNNCDRIGES-CRPGLCGPGKCMNTADSYKCAC 412 + C+C PG G C E +P LC G+C+NTA S++C C Sbjct: 2232 FACVCPPGMRPLPGSGEGCTDDNECHAQPDLCVNGRCVNTAGSFRCDC 2279 Score = 39.5 bits (88), Expect = 0.007 Identities = 27/80 (33%), Positives = 33/80 (41%), Gaps = 9/80 (11%) Frame = +2 Query: 227 CAPNLCL-NNGVCQEALTEHGYVCLCAPGFGGNN----CDRIGESCRPGLCGPGKCMNTA 391 CA N+ L +NG C A GY C C GF C + E + LC G C N Sbjct: 1366 CAENVDLCDNGQCLNA--PGGYRCECEMGFDPTEDHRACQDVDECAQGNLCAFGSCENLP 1423 Query: 392 DSYKCACPVTYT----GKNC 439 ++C C Y G NC Sbjct: 1424 GMFRCICNGGYELDRGGGNC 1443 Score = 39.5 bits (88), Expect = 0.007 Identities = 22/69 (31%), Positives = 30/69 (43%), Gaps = 4/69 (5%) Frame = +2 Query: 233 PNLCLNNGVCQEALTEHGYVCLCAPGF----GGNNCDRIGESCRPGLCGPGKCMNTADSY 400 P C +G C T + C C GF G+ C+ + E P C G C N Y Sbjct: 2493 PGPCGAHGHCHN--TPGSFRCECHQGFTLVSSGHGCEDVNECDGPHRCQHG-CQNQLGGY 2549 Query: 401 KCACPVTYT 427 +C+CP +T Sbjct: 2550 RCSCPQGFT 2558 Score = 38.3 bits (85), Expect = 0.017 Identities = 22/60 (36%), Positives = 28/60 (46%), Gaps = 9/60 (15%) Frame = +2 Query: 287 YVCLCAPGFGGNN----CDRIGESC-RPGLCGPGKCMNTADSYKCACPVTY----TGKNC 439 Y C C PGF C + E GLC G+C+NT S++C C + GKNC Sbjct: 470 YHCRCYPGFQATPTRQACVDVDECIVSGGLCHLGRCVNTEGSFQCVCNAGFELSPDGKNC 529 Score = 38.3 bits (85), Expect = 0.017 Identities = 23/72 (31%), Positives = 33/72 (45%), Gaps = 5/72 (6%) Frame = +2 Query: 239 LCLNNGVCQ-EALTEHGYVCLCAPGFGGNNCDRIGESCRPGLCGPGKCMNTADSYKCACP 415 LC G + L G+ + P + + E+ PG+C G C+NT S++C CP Sbjct: 2055 LCPQEGSAAFQELCPFGHGAVPGPDDSREDVNECAEN--PGVCTNGVCVNTDGSFRCECP 2112 Query: 416 VTY----TGKNC 439 Y TG NC Sbjct: 2113 FGYSLDFTGINC 2124 Score = 37.1 bits (82), Expect = 0.039 Identities = 25/76 (32%), Positives = 33/76 (43%), Gaps = 5/76 (6%) Frame = +2 Query: 203 ENVQNCFTCAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNN----CDRIGE-SCRPGLCG 367 E+V C P+ C + CQ L GY C C GF ++ C E + P CG Sbjct: 2527 EDVNECD--GPHRCQHG--CQNQLG--GYRCSCPQGFTQHSQWAQCVDENECALSPPTCG 2580 Query: 368 PGKCMNTADSYKCACP 415 C NT ++C CP Sbjct: 2581 SASCRNTLGGFRCVCP 2596 Score = 36.7 bits (81), Expect = 0.052 Identities = 27/84 (32%), Positives = 35/84 (41%), Gaps = 5/84 (5%) Frame = +2 Query: 176 NIMALALEKENVQNCFTCAPNLCLNNGVCQEALTEHGYVCLCAPGFG---GNNCDRIGES 346 N ++ L E+V C + + C N C Y C C G+ G C E Sbjct: 1753 NYNSILLACEDVDECGS-RESPCQQNADCINI--PGSYRCKCTRGYKLSPGGACVGRNE- 1808 Query: 347 CR--PGLCGPGKCMNTADSYKCAC 412 CR P +C G CM+T SY C C Sbjct: 1809 CREIPNVCSHGDCMDTEGSYMCLC 1832 Score = 35.9 bits (79), Expect = 0.090 Identities = 17/50 (34%), Positives = 22/50 (44%), Gaps = 4/50 (8%) Frame = +2 Query: 275 TEHGYVCLCAPGF----GGNNCDRIGESCRPGLCGPGKCMNTADSYKCAC 412 TE + C+C GF G NC E +C G C+N S+ C C Sbjct: 508 TEGSFQCVCNAGFELSPDGKNCVDHNECATSTMCVNGVCLNEDGSFSCLC 557 Score = 35.9 bits (79), Expect = 0.090 Identities = 16/49 (32%), Positives = 23/49 (46%), Gaps = 3/49 (6%) Frame = +2 Query: 287 YVCLCAPGFGGNN--CDRIGESCRP-GLCGPGKCMNTADSYKCACPVTY 424 Y C C GF G+ C+ E LC G+C+N Y+C C + + Sbjct: 1345 YRCTCRQGFAGDGFFCEDRDECAENVDLCDNGQCLNAPGGYRCECEMGF 1393 Score = 35.5 bits (78), Expect = 0.12 Identities = 19/57 (33%), Positives = 26/57 (45%), Gaps = 6/57 (10%) Frame = +2 Query: 287 YVCLCAPGFGGNNCDRIGESCR--PGLCGPGKCMNTADSYKCACPVTY----TGKNC 439 + LC+ G G R C P +C G C N SY+C C + Y +GK+C Sbjct: 666 FQALCSSGLGITTDGRDINECALDPEVCANGVCENLRGSYRCVCNLGYEAGASGKDC 722 Score = 35.1 bits (77), Expect = 0.16 Identities = 16/40 (40%), Positives = 20/40 (50%), Gaps = 2/40 (5%) Frame = +2 Query: 305 PGFGGNNCDRIGESCR--PGLCGPGKCMNTADSYKCACPV 418 P C + E C+ PGLC G C+N S+ C CPV Sbjct: 238 PNIHTGACQDVDE-CQAVPGLCQGGSCVNMVGSFHCRCPV 276 Score = 35.1 bits (77), Expect = 0.16 Identities = 18/49 (36%), Positives = 24/49 (48%), Gaps = 2/49 (4%) Frame = +2 Query: 287 YVCLCAPGFGGNNCDRIGESCR--PGLCGPGKCMNTADSYKCACPVTYT 427 Y LC G G R + CR LC G+C+N+ S++C C YT Sbjct: 2347 YRKLCPHGSGYTAEGRDVDECRMLAHLCAHGECINSLGSFRCHCQAGYT 2395 Score = 34.3 bits (75), Expect = 0.27 Identities = 25/83 (30%), Positives = 36/83 (43%), Gaps = 7/83 (8%) Frame = +2 Query: 233 PNLCLNNGVCQEALTEHGYVCLCAPGF----GGNNCDRIGESCRPG--LCGP-GKCMNTA 391 P++CL+ G C+ T+ +VC C G+ G C + E C G C C+N Sbjct: 1246 PHICLH-GDCEN--TKGSFVCHCQLGYMVRKGATGCSDVDE-CEVGGHNCDSHASCLNIP 1301 Query: 392 DSYKCACPVTYTGKNCEVKQLIE 460 S+ C C + G E L E Sbjct: 1302 GSFSCRCLPGWVGDGFECHDLDE 1324 Score = 34.3 bits (75), Expect = 0.27 Identities = 17/52 (32%), Positives = 25/52 (48%), Gaps = 4/52 (7%) Frame = +2 Query: 287 YVCLCAPGFGGNN--CDRIGESC-RPGLCGP-GKCMNTADSYKCACPVTYTG 430 + C C PG+ G+ C + E + C P G C+N SY+C C + G Sbjct: 1304 FSCRCLPGWVGDGFECHDLDECVSQEHRCSPRGDCLNVPGSYRCTCRQGFAG 1355 Score = 33.9 bits (74), Expect = 0.36 Identities = 22/62 (35%), Positives = 27/62 (43%), Gaps = 3/62 (4%) Frame = +2 Query: 236 NLCLNNGVCQEALTEHGYVCLCAPGFGGN---NCDRIGESCRPGLCGPGKCMNTADSYKC 406 NLCLN G C T Y C C G+ + C + E C C G C+N +Y C Sbjct: 417 NLCLN-GRCLP--TPSSYRCECNVGYTQDVRGECIDVDE-CTSSPCHHGDCVNIPGTYHC 472 Query: 407 AC 412 C Sbjct: 473 RC 474 Score = 33.5 bits (73), Expect = 0.48 Identities = 22/69 (31%), Positives = 29/69 (42%), Gaps = 5/69 (7%) Frame = +2 Query: 233 PNLCLNNGVCQEALTEHGYVCLCAPGFGGN----NCDRIGE-SCRPGLCGPGKCMNTADS 397 P +C + G C G+ CLC GF C + E P +C G C NT S Sbjct: 1204 PRVC-DQGHCTNM--PGGHRCLCYDGFMATPDMRTCVDVDECDLNPHICLHGDCENTKGS 1260 Query: 398 YKCACPVTY 424 + C C + Y Sbjct: 1261 FVCHCQLGY 1269 Score = 32.3 bits (70), Expect = 1.1 Identities = 12/23 (52%), Positives = 15/23 (65%) Frame = +2 Query: 359 LCGPGKCMNTADSYKCACPVTYT 427 LC G+C+ T SY+C C V YT Sbjct: 418 LCLNGRCLPTPSSYRCECNVGYT 440 Score = 31.5 bits (68), Expect = 1.9 Identities = 28/83 (33%), Positives = 34/83 (40%), Gaps = 12/83 (14%) Frame = +2 Query: 233 PNLCLNNGVCQEALTEHGYVCLCAPGF----GGNNC-DRIGESC----RPGLCGPGKCMN 385 PNLCL G C + + CLC PGF G+ C D C G C K N Sbjct: 1977 PNLCLF-GTCTNS--PGSFQCLCPPGFVLSDNGHRCFDTRQSFCFTRFEAGKCSVPKAFN 2033 Query: 386 TADSYKCAC---PVTYTGKNCEV 445 T + +C C P G CE+ Sbjct: 2034 TTKT-RCCCSKRPGEGWGDPCEL 2055 Score = 31.1 bits (67), Expect = 2.6 Identities = 12/32 (37%), Positives = 17/32 (53%) Frame = +2 Query: 329 DRIGESCRPGLCGPGKCMNTADSYKCACPVTY 424 D GE P +C G C+N S++C CP + Sbjct: 1723 DECGEI--PAICANGICINQIGSFRCECPAGF 1752 Score = 30.7 bits (66), Expect = 3.4 Identities = 21/70 (30%), Positives = 30/70 (42%), Gaps = 6/70 (8%) Frame = +2 Query: 233 PNLCLNNGVCQEALTEHGYVCLCAPGFGGNN----CDRIGE-SCRPGLCGPGK-CMNTAD 394 P +C N G+C + + C C GF N+ C+ + E R C C+N Sbjct: 1729 PAICAN-GICINQIGS--FRCECPAGFNYNSILLACEDVDECGSRESPCQQNADCINIPG 1785 Query: 395 SYKCACPVTY 424 SY+C C Y Sbjct: 1786 SYRCKCTRGY 1795 Score = 30.7 bits (66), Expect = 3.4 Identities = 22/76 (28%), Positives = 31/76 (40%), Gaps = 5/76 (6%) Frame = +2 Query: 212 QNCFTCAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNN----CDRIGESC-RPGLCGPGK 376 +N +P C + C+ L G+ C+C GF + C + E R G C Sbjct: 2569 ENECALSPPTC-GSASCRNTLG--GFRCVCPSGFDFDQALGGCQDVDECAGRRGPCSYS- 2624 Query: 377 CMNTADSYKCACPVTY 424 C NT + C CP Y Sbjct: 2625 CANTPGGFLCGCPQGY 2640 Score = 29.5 bits (63), Expect = 7.8 Identities = 25/81 (30%), Positives = 36/81 (44%), Gaps = 6/81 (7%) Frame = +2 Query: 203 ENVQNCFTCAPNLCLNNGVCQEALTEHGYVCLCAPGFGGN----NCDRIGESCRP--GLC 364 E++ C + + LC +G C + + C C GF C I E CR G C Sbjct: 1112 EDIDEC-SLSDGLC-PHGQCVNVIG--AFQCSCHAGFQSTPDRQGCVDINE-CRVQNGGC 1166 Query: 365 GPGKCMNTADSYKCACPVTYT 427 C+NT SY+C+C Y+ Sbjct: 1167 DV-HCINTEGSYRCSCGQGYS 1186 >AY165863-1|AAO18145.1| 2809|Homo sapiens fibrillin-3 short form precursor transcript variant 1 protein. Length = 2809 Score = 56.0 bits (129), Expect = 8e-08 Identities = 30/67 (44%), Positives = 36/67 (53%), Gaps = 5/67 (7%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHG-YVCLCAPGF----GGNNCDRIGESCRPGLCGPGKCMNTA 391 CA + NGVC L E G + CLC PGF GG+ C I E PG+C G C NT Sbjct: 535 CATSTMCVNGVC---LNEDGSFSCLCKPGFLLAPGGHYCMDIDECQTPGICVNGHCTNTE 591 Query: 392 DSYKCAC 412 S++C C Sbjct: 592 GSFRCQC 598 Score = 49.6 bits (113), Expect = 7e-06 Identities = 32/103 (31%), Positives = 48/103 (46%), Gaps = 10/103 (9%) Frame = +2 Query: 203 ENVQNCFTCAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNN----CDRIGE-SCRPGLCG 367 E++ C P LC G C T + C C PG+ + C+ I E S +CG Sbjct: 1562 EDIDECQEL-PGLC-QGGDCVN--TFGSFQCECPPGYHLSEHTRICEDIDECSTHSSICG 1617 Query: 368 PGKCMNTADSYKCACPVTYT----GKNC-EVKQLIEYPAFTGS 481 PG C NT +Y C CP Y G NC ++++ + + + G+ Sbjct: 1618 PGTCYNTLGNYTCVCPAEYLQVNGGNNCMDMRKSVCFRHYNGT 1660 Score = 49.2 bits (112), Expect = 9e-06 Identities = 35/98 (35%), Positives = 44/98 (44%), Gaps = 12/98 (12%) Frame = +2 Query: 185 ALALEKENVQNCFTC--APNLCLNNGVCQEALTEHGYVCLCAPGFGGN-----NCDRIGE 343 AL ++ N + C +P+LC G C T + C C PG+ NC + E Sbjct: 1018 ALDAQERNCTDIDECRISPDLC-GQGTCVN--TPGSFECECFPGYESGFMLMKNCMDVDE 1074 Query: 344 SCR-PGLCGPGKCMNTADSYKCACP----VTYTGKNCE 442 R P LC G C NT SYKC CP +T G CE Sbjct: 1075 CARDPLLCRGGTCTNTDGSYKCQCPPGHELTAKGTACE 1112 Score = 48.0 bits (109), Expect = 2e-05 Identities = 28/66 (42%), Positives = 34/66 (51%), Gaps = 6/66 (9%) Frame = +2 Query: 233 PNLCLNNGVCQEALTEHGYVCLCAPGFG----GNNCDRIGESCR--PGLCGPGKCMNTAD 394 P LC +G C+ T + C CA GF NC I E CR P LCG G C+NT Sbjct: 994 PGLC-THGTCRN--TVGSFHCACAGGFALDAQERNCTDIDE-CRISPDLCGQGTCVNTPG 1049 Query: 395 SYKCAC 412 S++C C Sbjct: 1050 SFECEC 1055 Score = 44.8 bits (101), Expect = 2e-04 Identities = 21/44 (47%), Positives = 27/44 (61%), Gaps = 5/44 (11%) Frame = +2 Query: 299 CAPGFG---GNNCDRIGESCR--PGLCGPGKCMNTADSYKCACP 415 CA GF G CD + E C PG+C G+C+NTA S++C CP Sbjct: 855 CARGFARMTGVTCDDVNE-CESFPGVCPNGRCVNTAGSFRCECP 897 Score = 44.8 bits (101), Expect = 2e-04 Identities = 28/73 (38%), Positives = 35/73 (47%), Gaps = 5/73 (6%) Frame = +2 Query: 212 QNCFTCAP-NLCLNNGVCQEALTEHGYVCLCAPGF----GGNNCDRIGESCRPGLCGPGK 376 Q+ CA NLC G C+ + C+C G+ GG NC I E P C G Sbjct: 1403 QDVDECAQGNLCAF-GSCENL--PGMFRCICNGGYELDRGGGNCTDINECADPVNCINGV 1459 Query: 377 CMNTADSYKCACP 415 C+NT SY C+CP Sbjct: 1460 CINTPGSYLCSCP 1472 Score = 44.0 bits (99), Expect = 3e-04 Identities = 26/64 (40%), Positives = 32/64 (50%), Gaps = 4/64 (6%) Frame = +2 Query: 233 PNLCLNNGVCQEALTEHGYVCLCAPGFGGNN----CDRIGESCRPGLCGPGKCMNTADSY 400 PN+C ++G C + TE Y+CLC GF + C I E C CG G C N SY Sbjct: 1813 PNVC-SHGDCMD--TEGSYMCLCHRGFQASADQTLCMDIDE-CDRQPCGNGTCKNIIGSY 1868 Query: 401 KCAC 412 C C Sbjct: 1869 NCLC 1872 Score = 44.0 bits (99), Expect = 3e-04 Identities = 27/73 (36%), Positives = 36/73 (49%), Gaps = 3/73 (4%) Frame = +2 Query: 206 NVQNCFTCAPNLCLNNGVCQEALTEHGYVCLCAPGFG--GNNCDRIGE-SCRPGLCGPGK 376 + C + A CL G CQ E + C+C PGF ++C I E S P LC G Sbjct: 1929 DTNECLSLA-GTCLP-GTCQNL--EGSFRCICPPGFQVQSDHCIDIDECSEEPNLCLFGT 1984 Query: 377 CMNTADSYKCACP 415 C N+ S++C CP Sbjct: 1985 CTNSPGSFQCLCP 1997 Score = 43.6 bits (98), Expect = 4e-04 Identities = 27/77 (35%), Positives = 37/77 (48%), Gaps = 7/77 (9%) Frame = +2 Query: 203 ENVQNCFTCA--PNLCLNNGVCQEALTEHGYVCLCAPGFG----GNNCDRIGE-SCRPGL 361 +N + CA P LC G C T+ Y C C PG G C+ I E S GL Sbjct: 1067 KNCMDVDECARDPLLC-RGGTCTN--TDGSYKCQCPPGHELTAKGTACEDIDECSLSDGL 1123 Query: 362 CGPGKCMNTADSYKCAC 412 C G+C+N +++C+C Sbjct: 1124 CPHGQCVNVIGAFQCSC 1140 Score = 42.7 bits (96), Expect = 8e-04 Identities = 24/83 (28%), Positives = 37/83 (44%), Gaps = 5/83 (6%) Frame = +2 Query: 182 MALALEKENVQNCFTCAPNLCLNNGVCQEALTEHGYVCLCAPGF----GGNNCDRIGESC 349 + + + ++ C P +C N GVC+ Y C+C G+ G +C + E Sbjct: 674 LGITTDGRDINEC-ALDPEVCAN-GVCENL--RGSYRCVCNLGYEAGASGKDCTDVDECA 729 Query: 350 RPGL-CGPGKCMNTADSYKCACP 415 L C G C N+ SY C+CP Sbjct: 730 LNSLLCDNGWCQNSPGSYSCSCP 752 Score = 42.3 bits (95), Expect = 0.001 Identities = 26/71 (36%), Positives = 31/71 (43%), Gaps = 4/71 (5%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGN---NCDRIGE-SCRPGLCGPGKCMNTAD 394 C+ G C + G+ C CA GF C+ I E S P LC +C NT Sbjct: 2130 CSVGHPCGQGTCTNVIG--GFECACADGFEPGLMMTCEDIDECSLNPLLCA-FRCHNTEG 2186 Query: 395 SYKCACPVTYT 427 SY C CP YT Sbjct: 2187 SYLCTCPAGYT 2197 Score = 41.5 bits (93), Expect = 0.002 Identities = 27/72 (37%), Positives = 36/72 (50%), Gaps = 9/72 (12%) Frame = +2 Query: 251 NGVCQEALTEHGYVCLCAPGF-GGNNCDRIG-ESCRP---GLCGPGKCMNTADSYKCAC- 412 NG C+ + Y CLC PGF +N D + + C +C G C+NTA S+ C C Sbjct: 1858 NGTCKNIIGS--YNCLCFPGFVVTHNGDCVDFDECTTLVGQVCRFGHCLNTAGSFHCLCQ 1915 Query: 413 ---PVTYTGKNC 439 +T GKNC Sbjct: 1916 DGFELTADGKNC 1927 Score = 40.3 bits (90), Expect = 0.004 Identities = 25/71 (35%), Positives = 29/71 (40%), Gaps = 5/71 (7%) Frame = +2 Query: 218 CFTCAPNLCLNNGVCQEALTEHGYVCLCAPGF----GGNNCDRIGESCR-PGLCGPGKCM 382 C T +C G C T + CLC GF G NC E G C PG C Sbjct: 1890 CTTLVGQVC-RFGHCLN--TAGSFHCLCQDGFELTADGKNCVDTNECLSLAGTCLPGTCQ 1946 Query: 383 NTADSYKCACP 415 N S++C CP Sbjct: 1947 NLEGSFRCICP 1957 Score = 40.3 bits (90), Expect = 0.004 Identities = 26/75 (34%), Positives = 33/75 (44%), Gaps = 4/75 (5%) Frame = +2 Query: 200 KENVQNCFTCAPNLCLNNGVCQEALTEHGYVCLCAPG----FGGNNCDRIGESCRPGLCG 367 +E+V C P +C NGVC T+ + C C G F G NC E CG Sbjct: 2082 REDVNECAE-NPGVC-TNGVCVN--TDGSFRCECPFGYSLDFTGINCVDTDECSVGHPCG 2137 Query: 368 PGKCMNTADSYKCAC 412 G C N ++CAC Sbjct: 2138 QGTCTNVIGGFECAC 2152 Score = 39.9 bits (89), Expect = 0.006 Identities = 26/67 (38%), Positives = 29/67 (43%), Gaps = 5/67 (7%) Frame = +2 Query: 227 CAPN-LCLNNGVCQEALTEHGYVCLCAPGF----GGNNCDRIGESCRPGLCGPGKCMNTA 391 CA N L +NG CQ + Y C C PGF C + E C C G C N A Sbjct: 728 CALNSLLCDNGWCQNS--PGSYSCSCPPGFHFWQDTEICKDVDE-CLSSPCVSGVCRNLA 784 Query: 392 DSYKCAC 412 SY C C Sbjct: 785 GSYTCKC 791 Score = 39.9 bits (89), Expect = 0.006 Identities = 18/48 (37%), Positives = 25/48 (52%), Gaps = 6/48 (12%) Frame = +2 Query: 287 YVCLCAPGF-----GGNNCDRIGES-CRPGLCGPGKCMNTADSYKCAC 412 + C+C PG G C E +P LC G+C+NTA S++C C Sbjct: 2232 FACVCPPGMRPLPGSGEGCTDDNECHAQPDLCVNGRCVNTAGSFRCDC 2279 Score = 39.5 bits (88), Expect = 0.007 Identities = 27/80 (33%), Positives = 33/80 (41%), Gaps = 9/80 (11%) Frame = +2 Query: 227 CAPNLCL-NNGVCQEALTEHGYVCLCAPGFGGNN----CDRIGESCRPGLCGPGKCMNTA 391 CA N+ L +NG C A GY C C GF C + E + LC G C N Sbjct: 1366 CAENVDLCDNGQCLNA--PGGYRCECEMGFDPTEDHRACQDVDECAQGNLCAFGSCENLP 1423 Query: 392 DSYKCACPVTYT----GKNC 439 ++C C Y G NC Sbjct: 1424 GMFRCICNGGYELDRGGGNC 1443 Score = 39.5 bits (88), Expect = 0.007 Identities = 22/69 (31%), Positives = 30/69 (43%), Gaps = 4/69 (5%) Frame = +2 Query: 233 PNLCLNNGVCQEALTEHGYVCLCAPGF----GGNNCDRIGESCRPGLCGPGKCMNTADSY 400 P C +G C T + C C GF G+ C+ + E P C G C N Y Sbjct: 2493 PGPCGAHGHCHN--TPGSFRCECHQGFTLVSSGHGCEDVNECDGPHRCQHG-CQNQLGGY 2549 Query: 401 KCACPVTYT 427 +C+CP +T Sbjct: 2550 RCSCPQGFT 2558 Score = 38.3 bits (85), Expect = 0.017 Identities = 22/60 (36%), Positives = 28/60 (46%), Gaps = 9/60 (15%) Frame = +2 Query: 287 YVCLCAPGFGGNN----CDRIGESC-RPGLCGPGKCMNTADSYKCACPVTY----TGKNC 439 Y C C PGF C + E GLC G+C+NT S++C C + GKNC Sbjct: 470 YHCRCYPGFQATPTRQACVDVDECIVSGGLCHLGRCVNTEGSFQCVCNAGFELSPDGKNC 529 Score = 38.3 bits (85), Expect = 0.017 Identities = 23/72 (31%), Positives = 33/72 (45%), Gaps = 5/72 (6%) Frame = +2 Query: 239 LCLNNGVCQ-EALTEHGYVCLCAPGFGGNNCDRIGESCRPGLCGPGKCMNTADSYKCACP 415 LC G + L G+ + P + + E+ PG+C G C+NT S++C CP Sbjct: 2055 LCPQEGSAAFQELCPFGHGAVPGPDDSREDVNECAEN--PGVCTNGVCVNTDGSFRCECP 2112 Query: 416 VTY----TGKNC 439 Y TG NC Sbjct: 2113 FGYSLDFTGINC 2124 Score = 37.1 bits (82), Expect = 0.039 Identities = 25/76 (32%), Positives = 33/76 (43%), Gaps = 5/76 (6%) Frame = +2 Query: 203 ENVQNCFTCAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNN----CDRIGE-SCRPGLCG 367 E+V C P+ C + CQ L GY C C GF ++ C E + P CG Sbjct: 2527 EDVNECD--GPHRCQHG--CQNQLG--GYRCSCPQGFTQHSQWAQCVDENECALSPPTCG 2580 Query: 368 PGKCMNTADSYKCACP 415 C NT ++C CP Sbjct: 2581 SASCRNTLGGFRCVCP 2596 Score = 36.7 bits (81), Expect = 0.052 Identities = 27/84 (32%), Positives = 35/84 (41%), Gaps = 5/84 (5%) Frame = +2 Query: 176 NIMALALEKENVQNCFTCAPNLCLNNGVCQEALTEHGYVCLCAPGFG---GNNCDRIGES 346 N ++ L E+V C + + C N C Y C C G+ G C E Sbjct: 1753 NYNSILLACEDVDECGS-RESPCQQNADCINI--PGSYRCKCTRGYKLSPGGACVGRNE- 1808 Query: 347 CR--PGLCGPGKCMNTADSYKCAC 412 CR P +C G CM+T SY C C Sbjct: 1809 CREIPNVCSHGDCMDTEGSYMCLC 1832 Score = 35.9 bits (79), Expect = 0.090 Identities = 17/50 (34%), Positives = 22/50 (44%), Gaps = 4/50 (8%) Frame = +2 Query: 275 TEHGYVCLCAPGF----GGNNCDRIGESCRPGLCGPGKCMNTADSYKCAC 412 TE + C+C GF G NC E +C G C+N S+ C C Sbjct: 508 TEGSFQCVCNAGFELSPDGKNCVDHNECATSTMCVNGVCLNEDGSFSCLC 557 Score = 35.9 bits (79), Expect = 0.090 Identities = 16/49 (32%), Positives = 23/49 (46%), Gaps = 3/49 (6%) Frame = +2 Query: 287 YVCLCAPGFGGNN--CDRIGESCRP-GLCGPGKCMNTADSYKCACPVTY 424 Y C C GF G+ C+ E LC G+C+N Y+C C + + Sbjct: 1345 YRCTCRQGFAGDGFFCEDRDECAENVDLCDNGQCLNAPGGYRCECEMGF 1393 Score = 35.5 bits (78), Expect = 0.12 Identities = 19/57 (33%), Positives = 26/57 (45%), Gaps = 6/57 (10%) Frame = +2 Query: 287 YVCLCAPGFGGNNCDRIGESCR--PGLCGPGKCMNTADSYKCACPVTY----TGKNC 439 + LC+ G G R C P +C G C N SY+C C + Y +GK+C Sbjct: 666 FQALCSSGLGITTDGRDINECALDPEVCANGVCENLRGSYRCVCNLGYEAGASGKDC 722 Score = 35.1 bits (77), Expect = 0.16 Identities = 16/40 (40%), Positives = 20/40 (50%), Gaps = 2/40 (5%) Frame = +2 Query: 305 PGFGGNNCDRIGESCR--PGLCGPGKCMNTADSYKCACPV 418 P C + E C+ PGLC G C+N S+ C CPV Sbjct: 238 PNIHTGACQDVDE-CQAVPGLCQGGSCVNMVGSFHCRCPV 276 Score = 35.1 bits (77), Expect = 0.16 Identities = 18/49 (36%), Positives = 24/49 (48%), Gaps = 2/49 (4%) Frame = +2 Query: 287 YVCLCAPGFGGNNCDRIGESCR--PGLCGPGKCMNTADSYKCACPVTYT 427 Y LC G G R + CR LC G+C+N+ S++C C YT Sbjct: 2347 YRKLCPHGSGYTAEGRDVDECRMLAHLCAHGECINSLGSFRCHCQAGYT 2395 Score = 34.3 bits (75), Expect = 0.27 Identities = 25/83 (30%), Positives = 36/83 (43%), Gaps = 7/83 (8%) Frame = +2 Query: 233 PNLCLNNGVCQEALTEHGYVCLCAPGF----GGNNCDRIGESCRPG--LCGP-GKCMNTA 391 P++CL+ G C+ T+ +VC C G+ G C + E C G C C+N Sbjct: 1246 PHICLH-GDCEN--TKGSFVCHCQLGYMVRKGATGCSDVDE-CEVGGHNCDSHASCLNIP 1301 Query: 392 DSYKCACPVTYTGKNCEVKQLIE 460 S+ C C + G E L E Sbjct: 1302 GSFSCRCLPGWVGDGFECHDLDE 1324 Score = 34.3 bits (75), Expect = 0.27 Identities = 17/52 (32%), Positives = 25/52 (48%), Gaps = 4/52 (7%) Frame = +2 Query: 287 YVCLCAPGFGGNN--CDRIGESC-RPGLCGP-GKCMNTADSYKCACPVTYTG 430 + C C PG+ G+ C + E + C P G C+N SY+C C + G Sbjct: 1304 FSCRCLPGWVGDGFECHDLDECVSQEHRCSPRGDCLNVPGSYRCTCRQGFAG 1355 Score = 33.9 bits (74), Expect = 0.36 Identities = 22/62 (35%), Positives = 27/62 (43%), Gaps = 3/62 (4%) Frame = +2 Query: 236 NLCLNNGVCQEALTEHGYVCLCAPGFGGN---NCDRIGESCRPGLCGPGKCMNTADSYKC 406 NLCLN G C T Y C C G+ + C + E C C G C+N +Y C Sbjct: 417 NLCLN-GRCLP--TPSSYRCECNVGYTQDVRGECIDVDE-CTSSPCHHGDCVNIPGTYHC 472 Query: 407 AC 412 C Sbjct: 473 RC 474 Score = 33.5 bits (73), Expect = 0.48 Identities = 22/69 (31%), Positives = 29/69 (42%), Gaps = 5/69 (7%) Frame = +2 Query: 233 PNLCLNNGVCQEALTEHGYVCLCAPGFGGN----NCDRIGE-SCRPGLCGPGKCMNTADS 397 P +C + G C G+ CLC GF C + E P +C G C NT S Sbjct: 1204 PRVC-DQGHCTNM--PGGHRCLCYDGFMATPDMRTCVDVDECDLNPHICLHGDCENTKGS 1260 Query: 398 YKCACPVTY 424 + C C + Y Sbjct: 1261 FVCHCQLGY 1269 Score = 32.3 bits (70), Expect = 1.1 Identities = 12/23 (52%), Positives = 15/23 (65%) Frame = +2 Query: 359 LCGPGKCMNTADSYKCACPVTYT 427 LC G+C+ T SY+C C V YT Sbjct: 418 LCLNGRCLPTPSSYRCECNVGYT 440 Score = 31.5 bits (68), Expect = 1.9 Identities = 28/83 (33%), Positives = 34/83 (40%), Gaps = 12/83 (14%) Frame = +2 Query: 233 PNLCLNNGVCQEALTEHGYVCLCAPGF----GGNNC-DRIGESC----RPGLCGPGKCMN 385 PNLCL G C + + CLC PGF G+ C D C G C K N Sbjct: 1977 PNLCLF-GTCTNS--PGSFQCLCPPGFVLSDNGHRCFDTRQSFCFTRFEAGKCSVPKAFN 2033 Query: 386 TADSYKCAC---PVTYTGKNCEV 445 T + +C C P G CE+ Sbjct: 2034 TTKT-RCCCSKRPGEGWGDPCEL 2055 Score = 31.1 bits (67), Expect = 2.6 Identities = 12/32 (37%), Positives = 17/32 (53%) Frame = +2 Query: 329 DRIGESCRPGLCGPGKCMNTADSYKCACPVTY 424 D GE P +C G C+N S++C CP + Sbjct: 1723 DECGEI--PAICANGICINQIGSFRCECPAGF 1752 Score = 30.7 bits (66), Expect = 3.4 Identities = 21/70 (30%), Positives = 30/70 (42%), Gaps = 6/70 (8%) Frame = +2 Query: 233 PNLCLNNGVCQEALTEHGYVCLCAPGFGGNN----CDRIGE-SCRPGLCGPGK-CMNTAD 394 P +C N G+C + + C C GF N+ C+ + E R C C+N Sbjct: 1729 PAICAN-GICINQIGS--FRCECPAGFNYNSILLACEDVDECGSRESPCQQNADCINIPG 1785 Query: 395 SYKCACPVTY 424 SY+C C Y Sbjct: 1786 SYRCKCTRGY 1795 Score = 30.7 bits (66), Expect = 3.4 Identities = 22/76 (28%), Positives = 31/76 (40%), Gaps = 5/76 (6%) Frame = +2 Query: 212 QNCFTCAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNN----CDRIGESC-RPGLCGPGK 376 +N +P C + C+ L G+ C+C GF + C + E R G C Sbjct: 2569 ENECALSPPTC-GSASCRNTLG--GFRCVCPSGFDFDQALGGCQDVDECAGRRGPCSYS- 2624 Query: 377 CMNTADSYKCACPVTY 424 C NT + C CP Y Sbjct: 2625 CANTPGGFLCGCPQGY 2640 Score = 29.5 bits (63), Expect = 7.8 Identities = 25/81 (30%), Positives = 36/81 (44%), Gaps = 6/81 (7%) Frame = +2 Query: 203 ENVQNCFTCAPNLCLNNGVCQEALTEHGYVCLCAPGFGGN----NCDRIGESCRP--GLC 364 E++ C + + LC +G C + + C C GF C I E CR G C Sbjct: 1112 EDIDEC-SLSDGLC-PHGQCVNVIG--AFQCSCHAGFQSTPDRQGCVDINE-CRVQNGGC 1166 Query: 365 GPGKCMNTADSYKCACPVTYT 427 C+NT SY+C+C Y+ Sbjct: 1167 DV-HCINTEGSYRCSCGQGYS 1186 >AL592307-2|CAH73994.1| 230|Homo sapiens Notch homolog 2 (Drosophila) N-terminal like protein. Length = 230 Score = 56.0 bits (129), Expect = 8e-08 Identities = 35/99 (35%), Positives = 44/99 (44%), Gaps = 6/99 (6%) Frame = +2 Query: 203 ENVQNCFTCAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCD-RIGESC---RPGLCGP 370 E Q+ C N C N G C C CA GF G +C C RP L G Sbjct: 21 EYCQHRDPCEKNRCQNGGTCVAQAMLGKATCRCASGFTGEDCQYSTSHPCFVSRPCLNG- 79 Query: 371 GKC-MNTADSYKCACPVTYTGKNCE-VKQLIEYPAFTGS 481 G C M + D+Y+C C V +TGK C+ + +P GS Sbjct: 80 GTCHMLSRDTYECTCQVGFTGKECQWTDACLSHPCANGS 118 Score = 50.0 bits (114), Expect = 5e-06 Identities = 24/74 (32%), Positives = 33/74 (44%), Gaps = 2/74 (2%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCR-PGLCGPG-KCMNTADSY 400 C + C N C + + C C GF G C+ C PG C G C+N SY Sbjct: 109 CLSHPCANGSTCTTVANQ--FSCKCLTGFTGQKCETDVNECDIPGHCQHGGTCLNLPGSY 166 Query: 401 KCACPVTYTGKNCE 442 +C C +TG+ C+ Sbjct: 167 QCQCLQGFTGQYCD 180 Score = 42.7 bits (96), Expect = 8e-04 Identities = 23/67 (34%), Positives = 29/67 (43%), Gaps = 3/67 (4%) Frame = +2 Query: 233 PNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLC-GPGKCMNTAD-SYKC 406 P C + G C Y C C GF G CD + C P C G C T D +++C Sbjct: 150 PGHCQHGGTCLNL--PGSYQCQCLQGFTGQYCDSLYVPCAPSPCVNGGTCRQTGDFTFEC 207 Query: 407 AC-PVTY 424 C P T+ Sbjct: 208 NCLPATW 214 >AL592307-1|CAH73993.1| 236|Homo sapiens Notch homolog 2 (Drosophila) N-terminal like protein. Length = 236 Score = 56.0 bits (129), Expect = 8e-08 Identities = 35/99 (35%), Positives = 44/99 (44%), Gaps = 6/99 (6%) Frame = +2 Query: 203 ENVQNCFTCAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCD-RIGESC---RPGLCGP 370 E Q+ C N C N G C C CA GF G +C C RP L G Sbjct: 21 EYCQHRDPCEKNRCQNGGTCVAQAMLGKATCRCASGFTGEDCQYSTSHPCFVSRPCLNG- 79 Query: 371 GKC-MNTADSYKCACPVTYTGKNCE-VKQLIEYPAFTGS 481 G C M + D+Y+C C V +TGK C+ + +P GS Sbjct: 80 GTCHMLSRDTYECTCQVGFTGKECQWTDACLSHPCANGS 118 Score = 50.0 bits (114), Expect = 5e-06 Identities = 24/74 (32%), Positives = 33/74 (44%), Gaps = 2/74 (2%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCR-PGLCGPG-KCMNTADSY 400 C + C N C + + C C GF G C+ C PG C G C+N SY Sbjct: 109 CLSHPCANGSTCTTVANQ--FSCKCLTGFTGQKCETDVNECDIPGHCQHGGTCLNLPGSY 166 Query: 401 KCACPVTYTGKNCE 442 +C C +TG+ C+ Sbjct: 167 QCQCLQGFTGQYCD 180 Score = 41.5 bits (93), Expect = 0.002 Identities = 21/62 (33%), Positives = 26/62 (41%), Gaps = 2/62 (3%) Frame = +2 Query: 233 PNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLC-GPGKCMNTAD-SYKC 406 P C + G C Y C C GF G CD + C P C G C T D +++C Sbjct: 150 PGHCQHGGTCLNL--PGSYQCQCLQGFTGQYCDSLYVPCAPSPCVNGGTCRQTGDFTFEC 207 Query: 407 AC 412 C Sbjct: 208 NC 209 >AK075065-1|BAC11381.1| 269|Homo sapiens protein ( Homo sapiens cDNA FLJ90584 fis, clone PLACE1000740, highly similar to Neurogenic locus notch homolog protein 2 precursor. ). Length = 269 Score = 56.0 bits (129), Expect = 8e-08 Identities = 35/99 (35%), Positives = 44/99 (44%), Gaps = 6/99 (6%) Frame = +2 Query: 203 ENVQNCFTCAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCD-RIGESC---RPGLCGP 370 E Q+ C N C N G C C CA GF G +C C RP L G Sbjct: 60 EYCQHRDPCEKNRCQNGGTCVAQAMLGKATCRCASGFTGEDCQYSTSHPCFVSRPCLNG- 118 Query: 371 GKC-MNTADSYKCACPVTYTGKNCE-VKQLIEYPAFTGS 481 G C M + D+Y+C C V +TGK C+ + +P GS Sbjct: 119 GTCHMLSRDTYECTCQVGFTGKECQWTDACLSHPCANGS 157 Score = 50.0 bits (114), Expect = 5e-06 Identities = 24/74 (32%), Positives = 33/74 (44%), Gaps = 2/74 (2%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCR-PGLCGPG-KCMNTADSY 400 C + C N C + + C C GF G C+ C PG C G C+N SY Sbjct: 148 CLSHPCANGSTCTTVANQ--FSCKCLTGFTGQKCETDVNECDIPGHCQHGGTCLNLPGSY 205 Query: 401 KCACPVTYTGKNCE 442 +C C +TG+ C+ Sbjct: 206 QCQCLQGFTGQYCD 219 Score = 42.7 bits (96), Expect = 8e-04 Identities = 23/67 (34%), Positives = 29/67 (43%), Gaps = 3/67 (4%) Frame = +2 Query: 233 PNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLC-GPGKCMNTAD-SYKC 406 P C + G C Y C C GF G CD + C P C G C T D +++C Sbjct: 189 PGHCQHGGTCLNL--PGSYQCQCLQGFTGQYCDSLYVPCAPSPCVNGGTCRQTGDFTFEC 246 Query: 407 AC-PVTY 424 C P T+ Sbjct: 247 NCLPATW 253 >AB177800-1|BAD16736.1| 2809|Homo sapiens fibrillin 3 protein. Length = 2809 Score = 56.0 bits (129), Expect = 8e-08 Identities = 30/67 (44%), Positives = 36/67 (53%), Gaps = 5/67 (7%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHG-YVCLCAPGF----GGNNCDRIGESCRPGLCGPGKCMNTA 391 CA + NGVC L E G + CLC PGF GG+ C I E PG+C G C NT Sbjct: 535 CATSTMCVNGVC---LNEDGSFSCLCKPGFLLAPGGHYCMDIDECQTPGICVNGHCTNTE 591 Query: 392 DSYKCAC 412 S++C C Sbjct: 592 GSFRCQC 598 Score = 49.6 bits (113), Expect = 7e-06 Identities = 32/103 (31%), Positives = 48/103 (46%), Gaps = 10/103 (9%) Frame = +2 Query: 203 ENVQNCFTCAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNN----CDRIGE-SCRPGLCG 367 E++ C P LC G C T + C C PG+ + C+ I E S +CG Sbjct: 1562 EDIDECQEL-PGLC-QGGDCVN--TFGSFQCECPPGYHLSEHTRICEDIDECSTHSSICG 1617 Query: 368 PGKCMNTADSYKCACPVTYT----GKNC-EVKQLIEYPAFTGS 481 PG C NT +Y C CP Y G NC ++++ + + + G+ Sbjct: 1618 PGTCYNTLGNYTCVCPAEYLQVNGGNNCMDMRKSVCFRHYNGT 1660 Score = 49.2 bits (112), Expect = 9e-06 Identities = 35/98 (35%), Positives = 44/98 (44%), Gaps = 12/98 (12%) Frame = +2 Query: 185 ALALEKENVQNCFTC--APNLCLNNGVCQEALTEHGYVCLCAPGFGGN-----NCDRIGE 343 AL ++ N + C +P+LC G C T + C C PG+ NC + E Sbjct: 1018 ALDAQERNCTDIDECRISPDLC-GQGTCVN--TPGSFECECFPGYESGFMLMKNCMDVDE 1074 Query: 344 SCR-PGLCGPGKCMNTADSYKCACP----VTYTGKNCE 442 R P LC G C NT SYKC CP +T G CE Sbjct: 1075 CARDPLLCWGGTCTNTDGSYKCQCPPGHELTAKGTACE 1112 Score = 48.0 bits (109), Expect = 2e-05 Identities = 28/66 (42%), Positives = 34/66 (51%), Gaps = 6/66 (9%) Frame = +2 Query: 233 PNLCLNNGVCQEALTEHGYVCLCAPGFG----GNNCDRIGESCR--PGLCGPGKCMNTAD 394 P LC +G C+ T + C CA GF NC I E CR P LCG G C+NT Sbjct: 994 PGLC-THGTCRN--TVGSFHCACAGGFALDAQERNCTDIDE-CRISPDLCGQGTCVNTPG 1049 Query: 395 SYKCAC 412 S++C C Sbjct: 1050 SFECEC 1055 Score = 44.8 bits (101), Expect = 2e-04 Identities = 21/44 (47%), Positives = 27/44 (61%), Gaps = 5/44 (11%) Frame = +2 Query: 299 CAPGFG---GNNCDRIGESCR--PGLCGPGKCMNTADSYKCACP 415 CA GF G CD + E C PG+C G+C+NTA S++C CP Sbjct: 855 CARGFARMTGVTCDDVNE-CESFPGVCPNGRCVNTAGSFRCECP 897 Score = 44.8 bits (101), Expect = 2e-04 Identities = 28/73 (38%), Positives = 35/73 (47%), Gaps = 5/73 (6%) Frame = +2 Query: 212 QNCFTCAP-NLCLNNGVCQEALTEHGYVCLCAPGF----GGNNCDRIGESCRPGLCGPGK 376 Q+ CA NLC G C+ + C+C G+ GG NC I E P C G Sbjct: 1403 QDVDECAQGNLCAF-GSCENL--PGMFRCICNGGYELDRGGGNCTDINECADPVNCINGV 1459 Query: 377 CMNTADSYKCACP 415 C+NT SY C+CP Sbjct: 1460 CINTPGSYLCSCP 1472 Score = 44.0 bits (99), Expect = 3e-04 Identities = 26/64 (40%), Positives = 32/64 (50%), Gaps = 4/64 (6%) Frame = +2 Query: 233 PNLCLNNGVCQEALTEHGYVCLCAPGFGGNN----CDRIGESCRPGLCGPGKCMNTADSY 400 PN+C ++G C + TE Y+CLC GF + C I E C CG G C N SY Sbjct: 1813 PNVC-SHGDCMD--TEGSYMCLCHRGFQASADQTLCMDIDE-CDRQPCGNGTCKNIIGSY 1868 Query: 401 KCAC 412 C C Sbjct: 1869 NCLC 1872 Score = 44.0 bits (99), Expect = 3e-04 Identities = 27/73 (36%), Positives = 36/73 (49%), Gaps = 3/73 (4%) Frame = +2 Query: 206 NVQNCFTCAPNLCLNNGVCQEALTEHGYVCLCAPGFG--GNNCDRIGE-SCRPGLCGPGK 376 + C + A CL G CQ E + C+C PGF ++C I E S P LC G Sbjct: 1929 DTNECLSLA-GTCLP-GTCQNL--EGSFRCICPPGFQVQSDHCIDIDECSEEPNLCLFGT 1984 Query: 377 CMNTADSYKCACP 415 C N+ S++C CP Sbjct: 1985 CTNSPGSFQCLCP 1997 Score = 42.7 bits (96), Expect = 8e-04 Identities = 24/83 (28%), Positives = 37/83 (44%), Gaps = 5/83 (6%) Frame = +2 Query: 182 MALALEKENVQNCFTCAPNLCLNNGVCQEALTEHGYVCLCAPGF----GGNNCDRIGESC 349 + + + ++ C P +C N GVC+ Y C+C G+ G +C + E Sbjct: 674 LGITTDGRDINEC-ALDPEVCAN-GVCENL--RGSYRCVCNLGYEAGASGKDCTDVDECA 729 Query: 350 RPGL-CGPGKCMNTADSYKCACP 415 L C G C N+ SY C+CP Sbjct: 730 LNSLLCDNGWCQNSPGSYSCSCP 752 Score = 42.7 bits (96), Expect = 8e-04 Identities = 27/77 (35%), Positives = 37/77 (48%), Gaps = 7/77 (9%) Frame = +2 Query: 203 ENVQNCFTCA--PNLCLNNGVCQEALTEHGYVCLCAPGFG----GNNCDRIGE-SCRPGL 361 +N + CA P LC G C T+ Y C C PG G C+ I E S GL Sbjct: 1067 KNCMDVDECARDPLLCWG-GTCTN--TDGSYKCQCPPGHELTAKGTACEDIDECSLSDGL 1123 Query: 362 CGPGKCMNTADSYKCAC 412 C G+C+N +++C+C Sbjct: 1124 CPHGQCVNVIGAFQCSC 1140 Score = 42.3 bits (95), Expect = 0.001 Identities = 26/71 (36%), Positives = 31/71 (43%), Gaps = 4/71 (5%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGN---NCDRIGE-SCRPGLCGPGKCMNTAD 394 C+ G C + G+ C CA GF C+ I E S P LC +C NT Sbjct: 2130 CSVGHPCGQGTCTNVIG--GFECACADGFEPGLMMTCEDIDECSLNPLLCA-FRCHNTEG 2186 Query: 395 SYKCACPVTYT 427 SY C CP YT Sbjct: 2187 SYLCTCPAGYT 2197 Score = 41.5 bits (93), Expect = 0.002 Identities = 27/72 (37%), Positives = 36/72 (50%), Gaps = 9/72 (12%) Frame = +2 Query: 251 NGVCQEALTEHGYVCLCAPGF-GGNNCDRIG-ESCRP---GLCGPGKCMNTADSYKCAC- 412 NG C+ + Y CLC PGF +N D + + C +C G C+NTA S+ C C Sbjct: 1858 NGTCKNIIGS--YNCLCFPGFVVTHNGDCVDFDECTTLVGQVCRFGHCLNTAGSFHCLCQ 1915 Query: 413 ---PVTYTGKNC 439 +T GKNC Sbjct: 1916 DGFELTADGKNC 1927 Score = 40.3 bits (90), Expect = 0.004 Identities = 25/71 (35%), Positives = 29/71 (40%), Gaps = 5/71 (7%) Frame = +2 Query: 218 CFTCAPNLCLNNGVCQEALTEHGYVCLCAPGF----GGNNCDRIGESCR-PGLCGPGKCM 382 C T +C G C T + CLC GF G NC E G C PG C Sbjct: 1890 CTTLVGQVC-RFGHCLN--TAGSFHCLCQDGFELTADGKNCVDTNECLSLAGTCLPGTCQ 1946 Query: 383 NTADSYKCACP 415 N S++C CP Sbjct: 1947 NLEGSFRCICP 1957 Score = 40.3 bits (90), Expect = 0.004 Identities = 26/75 (34%), Positives = 33/75 (44%), Gaps = 4/75 (5%) Frame = +2 Query: 200 KENVQNCFTCAPNLCLNNGVCQEALTEHGYVCLCAPG----FGGNNCDRIGESCRPGLCG 367 +E+V C P +C NGVC T+ + C C G F G NC E CG Sbjct: 2082 REDVNECAE-NPGVC-TNGVCVN--TDGSFRCECPFGYSLDFTGINCVDTDECSVGHPCG 2137 Query: 368 PGKCMNTADSYKCAC 412 G C N ++CAC Sbjct: 2138 QGTCTNVIGGFECAC 2152 Score = 39.9 bits (89), Expect = 0.006 Identities = 26/67 (38%), Positives = 29/67 (43%), Gaps = 5/67 (7%) Frame = +2 Query: 227 CAPN-LCLNNGVCQEALTEHGYVCLCAPGF----GGNNCDRIGESCRPGLCGPGKCMNTA 391 CA N L +NG CQ + Y C C PGF C + E C C G C N A Sbjct: 728 CALNSLLCDNGWCQNS--PGSYSCSCPPGFHFWQDTEICKDVDE-CLSSPCVSGVCRNLA 784 Query: 392 DSYKCAC 412 SY C C Sbjct: 785 GSYTCKC 791 Score = 39.9 bits (89), Expect = 0.006 Identities = 18/48 (37%), Positives = 25/48 (52%), Gaps = 6/48 (12%) Frame = +2 Query: 287 YVCLCAPGF-----GGNNCDRIGES-CRPGLCGPGKCMNTADSYKCAC 412 + C+C PG G C E +P LC G+C+NTA S++C C Sbjct: 2232 FACVCPPGMRPLPGSGEGCTDDNECHAQPDLCVNGRCVNTAGSFRCDC 2279 Score = 39.5 bits (88), Expect = 0.007 Identities = 27/80 (33%), Positives = 33/80 (41%), Gaps = 9/80 (11%) Frame = +2 Query: 227 CAPNLCL-NNGVCQEALTEHGYVCLCAPGFGGNN----CDRIGESCRPGLCGPGKCMNTA 391 CA N+ L +NG C A GY C C GF C + E + LC G C N Sbjct: 1366 CAENVDLCDNGQCLNA--PGGYRCECEMGFDPTEDHRACQDVDECAQGNLCAFGSCENLP 1423 Query: 392 DSYKCACPVTYT----GKNC 439 ++C C Y G NC Sbjct: 1424 GMFRCICNGGYELDRGGGNC 1443 Score = 39.5 bits (88), Expect = 0.007 Identities = 22/69 (31%), Positives = 30/69 (43%), Gaps = 4/69 (5%) Frame = +2 Query: 233 PNLCLNNGVCQEALTEHGYVCLCAPGF----GGNNCDRIGESCRPGLCGPGKCMNTADSY 400 P C +G C T + C C GF G+ C+ + E P C G C N Y Sbjct: 2493 PGPCGAHGHCHN--TPGSFRCECHQGFTLVSSGHGCEDVNECDGPHRCQHG-CQNQLGGY 2549 Query: 401 KCACPVTYT 427 +C+CP +T Sbjct: 2550 RCSCPQGFT 2558 Score = 38.3 bits (85), Expect = 0.017 Identities = 22/60 (36%), Positives = 28/60 (46%), Gaps = 9/60 (15%) Frame = +2 Query: 287 YVCLCAPGFGGNN----CDRIGESC-RPGLCGPGKCMNTADSYKCACPVTY----TGKNC 439 Y C C PGF C + E GLC G+C+NT S++C C + GKNC Sbjct: 470 YHCRCYPGFQATPTRQACVDVDECIVSGGLCHLGRCVNTEGSFQCVCNAGFELSPDGKNC 529 Score = 38.3 bits (85), Expect = 0.017 Identities = 23/72 (31%), Positives = 33/72 (45%), Gaps = 5/72 (6%) Frame = +2 Query: 239 LCLNNGVCQ-EALTEHGYVCLCAPGFGGNNCDRIGESCRPGLCGPGKCMNTADSYKCACP 415 LC G + L G+ + P + + E+ PG+C G C+NT S++C CP Sbjct: 2055 LCPQEGSAAFQELCPFGHGAVPGPDDSREDVNECAEN--PGVCTNGVCVNTDGSFRCECP 2112 Query: 416 VTY----TGKNC 439 Y TG NC Sbjct: 2113 FGYSLDFTGINC 2124 Score = 37.1 bits (82), Expect = 0.039 Identities = 25/76 (32%), Positives = 33/76 (43%), Gaps = 5/76 (6%) Frame = +2 Query: 203 ENVQNCFTCAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNN----CDRIGE-SCRPGLCG 367 E+V C P+ C + CQ L GY C C GF ++ C E + P CG Sbjct: 2527 EDVNECD--GPHRCQHG--CQNQLG--GYRCSCPQGFTQHSQWAQCVDENECALSPPTCG 2580 Query: 368 PGKCMNTADSYKCACP 415 C NT ++C CP Sbjct: 2581 SASCRNTLGGFRCVCP 2596 Score = 36.7 bits (81), Expect = 0.052 Identities = 27/84 (32%), Positives = 35/84 (41%), Gaps = 5/84 (5%) Frame = +2 Query: 176 NIMALALEKENVQNCFTCAPNLCLNNGVCQEALTEHGYVCLCAPGFG---GNNCDRIGES 346 N ++ L E+V C + + C N C Y C C G+ G C E Sbjct: 1753 NYNSILLACEDVDECGS-RESPCQQNADCINI--PGSYRCKCTRGYKLSPGGACVGRNE- 1808 Query: 347 CR--PGLCGPGKCMNTADSYKCAC 412 CR P +C G CM+T SY C C Sbjct: 1809 CREIPNVCSHGDCMDTEGSYMCLC 1832 Score = 35.9 bits (79), Expect = 0.090 Identities = 17/50 (34%), Positives = 22/50 (44%), Gaps = 4/50 (8%) Frame = +2 Query: 275 TEHGYVCLCAPGF----GGNNCDRIGESCRPGLCGPGKCMNTADSYKCAC 412 TE + C+C GF G NC E +C G C+N S+ C C Sbjct: 508 TEGSFQCVCNAGFELSPDGKNCVDHNECATSTMCVNGVCLNEDGSFSCLC 557 Score = 35.9 bits (79), Expect = 0.090 Identities = 16/49 (32%), Positives = 23/49 (46%), Gaps = 3/49 (6%) Frame = +2 Query: 287 YVCLCAPGFGGNN--CDRIGESCRP-GLCGPGKCMNTADSYKCACPVTY 424 Y C C GF G+ C+ E LC G+C+N Y+C C + + Sbjct: 1345 YRCTCRQGFAGDGFFCEDRDECAENVDLCDNGQCLNAPGGYRCECEMGF 1393 Score = 35.5 bits (78), Expect = 0.12 Identities = 19/57 (33%), Positives = 26/57 (45%), Gaps = 6/57 (10%) Frame = +2 Query: 287 YVCLCAPGFGGNNCDRIGESCR--PGLCGPGKCMNTADSYKCACPVTY----TGKNC 439 + LC+ G G R C P +C G C N SY+C C + Y +GK+C Sbjct: 666 FQALCSSGLGITTDGRDINECALDPEVCANGVCENLRGSYRCVCNLGYEAGASGKDC 722 Score = 35.1 bits (77), Expect = 0.16 Identities = 16/40 (40%), Positives = 20/40 (50%), Gaps = 2/40 (5%) Frame = +2 Query: 305 PGFGGNNCDRIGESCR--PGLCGPGKCMNTADSYKCACPV 418 P C + E C+ PGLC G C+N S+ C CPV Sbjct: 238 PNIHTGACQDVDE-CQAVPGLCQGGSCVNMVGSFHCRCPV 276 Score = 35.1 bits (77), Expect = 0.16 Identities = 18/49 (36%), Positives = 24/49 (48%), Gaps = 2/49 (4%) Frame = +2 Query: 287 YVCLCAPGFGGNNCDRIGESCR--PGLCGPGKCMNTADSYKCACPVTYT 427 Y LC G G R + CR LC G+C+N+ S++C C YT Sbjct: 2347 YRKLCPHGSGYTAEGRDVDECRMLAHLCAHGECINSLGSFRCHCQAGYT 2395 Score = 34.3 bits (75), Expect = 0.27 Identities = 25/83 (30%), Positives = 36/83 (43%), Gaps = 7/83 (8%) Frame = +2 Query: 233 PNLCLNNGVCQEALTEHGYVCLCAPGF----GGNNCDRIGESCRPG--LCGP-GKCMNTA 391 P++CL+ G C+ T+ +VC C G+ G C + E C G C C+N Sbjct: 1246 PHICLH-GDCEN--TKGSFVCHCQLGYMVRKGATGCSDVDE-CEVGGHNCDSHASCLNIP 1301 Query: 392 DSYKCACPVTYTGKNCEVKQLIE 460 S+ C C + G E L E Sbjct: 1302 GSFSCRCLPGWVGDGFECHDLDE 1324 Score = 34.3 bits (75), Expect = 0.27 Identities = 17/52 (32%), Positives = 25/52 (48%), Gaps = 4/52 (7%) Frame = +2 Query: 287 YVCLCAPGFGGNN--CDRIGESC-RPGLCGP-GKCMNTADSYKCACPVTYTG 430 + C C PG+ G+ C + E + C P G C+N SY+C C + G Sbjct: 1304 FSCRCLPGWVGDGFECHDLDECVSQEHRCSPRGDCLNVPGSYRCTCRQGFAG 1355 Score = 33.9 bits (74), Expect = 0.36 Identities = 22/62 (35%), Positives = 27/62 (43%), Gaps = 3/62 (4%) Frame = +2 Query: 236 NLCLNNGVCQEALTEHGYVCLCAPGFGGN---NCDRIGESCRPGLCGPGKCMNTADSYKC 406 NLCLN G C T Y C C G+ + C + E C C G C+N +Y C Sbjct: 417 NLCLN-GRCLP--TPSSYRCECNVGYTQDVRGECIDVDE-CTSSPCHHGDCVNIPGTYHC 472 Query: 407 AC 412 C Sbjct: 473 RC 474 Score = 33.5 bits (73), Expect = 0.48 Identities = 22/69 (31%), Positives = 29/69 (42%), Gaps = 5/69 (7%) Frame = +2 Query: 233 PNLCLNNGVCQEALTEHGYVCLCAPGFGGN----NCDRIGE-SCRPGLCGPGKCMNTADS 397 P +C + G C G+ CLC GF C + E P +C G C NT S Sbjct: 1204 PRVC-DQGHCTNM--PGGHRCLCYDGFMATPDMRTCVDVDECDLNPHICLHGDCENTKGS 1260 Query: 398 YKCACPVTY 424 + C C + Y Sbjct: 1261 FVCHCQLGY 1269 Score = 32.3 bits (70), Expect = 1.1 Identities = 12/23 (52%), Positives = 15/23 (65%) Frame = +2 Query: 359 LCGPGKCMNTADSYKCACPVTYT 427 LC G+C+ T SY+C C V YT Sbjct: 418 LCLNGRCLPTPSSYRCECNVGYT 440 Score = 31.5 bits (68), Expect = 1.9 Identities = 28/83 (33%), Positives = 34/83 (40%), Gaps = 12/83 (14%) Frame = +2 Query: 233 PNLCLNNGVCQEALTEHGYVCLCAPGF----GGNNC-DRIGESC----RPGLCGPGKCMN 385 PNLCL G C + + CLC PGF G+ C D C G C K N Sbjct: 1977 PNLCLF-GTCTNS--PGSFQCLCPPGFVLSDNGHRCFDTRQSFCFTRFEAGKCSVPKAFN 2033 Query: 386 TADSYKCAC---PVTYTGKNCEV 445 T + +C C P G CE+ Sbjct: 2034 TTKT-RCCCSKRPGEGWGDPCEL 2055 Score = 31.1 bits (67), Expect = 2.6 Identities = 12/32 (37%), Positives = 17/32 (53%) Frame = +2 Query: 329 DRIGESCRPGLCGPGKCMNTADSYKCACPVTY 424 D GE P +C G C+N S++C CP + Sbjct: 1723 DECGEI--PAICANGICINQIGSFRCECPAGF 1752 Score = 30.7 bits (66), Expect = 3.4 Identities = 21/70 (30%), Positives = 30/70 (42%), Gaps = 6/70 (8%) Frame = +2 Query: 233 PNLCLNNGVCQEALTEHGYVCLCAPGFGGNN----CDRIGE-SCRPGLCGPGK-CMNTAD 394 P +C N G+C + + C C GF N+ C+ + E R C C+N Sbjct: 1729 PAICAN-GICINQIGS--FRCECPAGFNYNSILLACEDVDECGSRESPCQQNADCINIPG 1785 Query: 395 SYKCACPVTY 424 SY+C C Y Sbjct: 1786 SYRCKCTRGY 1795 Score = 30.7 bits (66), Expect = 3.4 Identities = 22/76 (28%), Positives = 31/76 (40%), Gaps = 5/76 (6%) Frame = +2 Query: 212 QNCFTCAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNN----CDRIGESC-RPGLCGPGK 376 +N +P C + C+ L G+ C+C GF + C + E R G C Sbjct: 2569 ENECALSPPTC-GSASCRNTLG--GFRCVCPSGFDFDQALGGCQDVDECAGRRGPCSYS- 2624 Query: 377 CMNTADSYKCACPVTY 424 C NT + C CP Y Sbjct: 2625 CANTPGGFLCGCPQGY 2640 Score = 29.5 bits (63), Expect = 7.8 Identities = 25/81 (30%), Positives = 36/81 (44%), Gaps = 6/81 (7%) Frame = +2 Query: 203 ENVQNCFTCAPNLCLNNGVCQEALTEHGYVCLCAPGFGGN----NCDRIGESCRP--GLC 364 E++ C + + LC +G C + + C C GF C I E CR G C Sbjct: 1112 EDIDEC-SLSDGLC-PHGQCVNVIG--AFQCSCHAGFQSTPDRQGCVDINE-CRVQNGGC 1166 Query: 365 GPGKCMNTADSYKCACPVTYT 427 C+NT SY+C+C Y+ Sbjct: 1167 DV-HCINTEGSYRCSCGQGYS 1186 >AB177799-1|BAD16735.1| 2809|Homo sapiens fibrillin 3 protein. Length = 2809 Score = 56.0 bits (129), Expect = 8e-08 Identities = 30/67 (44%), Positives = 36/67 (53%), Gaps = 5/67 (7%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHG-YVCLCAPGF----GGNNCDRIGESCRPGLCGPGKCMNTA 391 CA + NGVC L E G + CLC PGF GG+ C I E PG+C G C NT Sbjct: 535 CATSTMCVNGVC---LNEDGSFSCLCKPGFLLAPGGHYCMDIDECQTPGICVNGHCTNTE 591 Query: 392 DSYKCAC 412 S++C C Sbjct: 592 GSFRCQC 598 Score = 49.6 bits (113), Expect = 7e-06 Identities = 32/103 (31%), Positives = 48/103 (46%), Gaps = 10/103 (9%) Frame = +2 Query: 203 ENVQNCFTCAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNN----CDRIGE-SCRPGLCG 367 E++ C P LC G C T + C C PG+ + C+ I E S +CG Sbjct: 1562 EDIDECQEL-PGLC-QGGDCVN--TFGSFQCECPPGYHLSEHTRICEDIDECSTHSSICG 1617 Query: 368 PGKCMNTADSYKCACPVTYT----GKNC-EVKQLIEYPAFTGS 481 PG C NT +Y C CP Y G NC ++++ + + + G+ Sbjct: 1618 PGTCYNTLGNYTCVCPAEYLQVNGGNNCMDMRKSVCFRHYNGT 1660 Score = 49.2 bits (112), Expect = 9e-06 Identities = 35/98 (35%), Positives = 44/98 (44%), Gaps = 12/98 (12%) Frame = +2 Query: 185 ALALEKENVQNCFTC--APNLCLNNGVCQEALTEHGYVCLCAPGFGGN-----NCDRIGE 343 AL ++ N + C +P+LC G C T + C C PG+ NC + E Sbjct: 1018 ALDAQERNCTDIDECRISPDLC-GQGTCVN--TPGSFECECFPGYESGFMLMKNCMDVDE 1074 Query: 344 SCR-PGLCGPGKCMNTADSYKCACP----VTYTGKNCE 442 R P LC G C NT SYKC CP +T G CE Sbjct: 1075 CARDPLLCRGGTCTNTDGSYKCQCPPGHELTAKGTACE 1112 Score = 48.0 bits (109), Expect = 2e-05 Identities = 28/66 (42%), Positives = 34/66 (51%), Gaps = 6/66 (9%) Frame = +2 Query: 233 PNLCLNNGVCQEALTEHGYVCLCAPGFG----GNNCDRIGESCR--PGLCGPGKCMNTAD 394 P LC +G C+ T + C CA GF NC I E CR P LCG G C+NT Sbjct: 994 PGLC-THGTCRN--TVGSFHCACAGGFALDAQERNCTDIDE-CRISPDLCGQGTCVNTPG 1049 Query: 395 SYKCAC 412 S++C C Sbjct: 1050 SFECEC 1055 Score = 44.8 bits (101), Expect = 2e-04 Identities = 21/44 (47%), Positives = 27/44 (61%), Gaps = 5/44 (11%) Frame = +2 Query: 299 CAPGFG---GNNCDRIGESCR--PGLCGPGKCMNTADSYKCACP 415 CA GF G CD + E C PG+C G+C+NTA S++C CP Sbjct: 855 CARGFARMTGVTCDDVNE-CESFPGVCPNGRCVNTAGSFRCECP 897 Score = 44.8 bits (101), Expect = 2e-04 Identities = 28/73 (38%), Positives = 35/73 (47%), Gaps = 5/73 (6%) Frame = +2 Query: 212 QNCFTCAP-NLCLNNGVCQEALTEHGYVCLCAPGF----GGNNCDRIGESCRPGLCGPGK 376 Q+ CA NLC G C+ + C+C G+ GG NC I E P C G Sbjct: 1403 QDVDECAQGNLCAF-GSCENL--PGMFRCICNGGYELDRGGGNCTDINECADPVNCINGV 1459 Query: 377 CMNTADSYKCACP 415 C+NT SY C+CP Sbjct: 1460 CINTPGSYLCSCP 1472 Score = 44.0 bits (99), Expect = 3e-04 Identities = 26/64 (40%), Positives = 32/64 (50%), Gaps = 4/64 (6%) Frame = +2 Query: 233 PNLCLNNGVCQEALTEHGYVCLCAPGFGGNN----CDRIGESCRPGLCGPGKCMNTADSY 400 PN+C ++G C + TE Y+CLC GF + C I E C CG G C N SY Sbjct: 1813 PNVC-SHGDCMD--TEGSYMCLCHRGFQASADQTLCMDIDE-CDRQPCGNGTCKNIIGSY 1868 Query: 401 KCAC 412 C C Sbjct: 1869 NCLC 1872 Score = 44.0 bits (99), Expect = 3e-04 Identities = 27/73 (36%), Positives = 36/73 (49%), Gaps = 3/73 (4%) Frame = +2 Query: 206 NVQNCFTCAPNLCLNNGVCQEALTEHGYVCLCAPGFG--GNNCDRIGE-SCRPGLCGPGK 376 + C + A CL G CQ E + C+C PGF ++C I E S P LC G Sbjct: 1929 DTNECLSLA-GTCLP-GTCQNL--EGSFRCICPPGFQVQSDHCIDIDECSEEPNLCLFGT 1984 Query: 377 CMNTADSYKCACP 415 C N+ S++C CP Sbjct: 1985 CTNSPGSFQCLCP 1997 Score = 43.6 bits (98), Expect = 4e-04 Identities = 27/77 (35%), Positives = 37/77 (48%), Gaps = 7/77 (9%) Frame = +2 Query: 203 ENVQNCFTCA--PNLCLNNGVCQEALTEHGYVCLCAPGFG----GNNCDRIGE-SCRPGL 361 +N + CA P LC G C T+ Y C C PG G C+ I E S GL Sbjct: 1067 KNCMDVDECARDPLLC-RGGTCTN--TDGSYKCQCPPGHELTAKGTACEDIDECSLSDGL 1123 Query: 362 CGPGKCMNTADSYKCAC 412 C G+C+N +++C+C Sbjct: 1124 CPHGQCVNVIGAFQCSC 1140 Score = 42.7 bits (96), Expect = 8e-04 Identities = 24/83 (28%), Positives = 37/83 (44%), Gaps = 5/83 (6%) Frame = +2 Query: 182 MALALEKENVQNCFTCAPNLCLNNGVCQEALTEHGYVCLCAPGF----GGNNCDRIGESC 349 + + + ++ C P +C N GVC+ Y C+C G+ G +C + E Sbjct: 674 LGITTDGRDINEC-ALDPEVCAN-GVCENL--RGSYRCVCNLGYEAGASGKDCTDVDECA 729 Query: 350 RPGL-CGPGKCMNTADSYKCACP 415 L C G C N+ SY C+CP Sbjct: 730 LNSLLCDNGWCQNSPGSYSCSCP 752 Score = 42.3 bits (95), Expect = 0.001 Identities = 26/71 (36%), Positives = 31/71 (43%), Gaps = 4/71 (5%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGN---NCDRIGE-SCRPGLCGPGKCMNTAD 394 C+ G C + G+ C CA GF C+ I E S P LC +C NT Sbjct: 2130 CSVGHPCGQGTCTNVIG--GFECACADGFEPGLMMTCEDIDECSLNPLLCA-FRCHNTEG 2186 Query: 395 SYKCACPVTYT 427 SY C CP YT Sbjct: 2187 SYLCTCPAGYT 2197 Score = 41.5 bits (93), Expect = 0.002 Identities = 27/72 (37%), Positives = 36/72 (50%), Gaps = 9/72 (12%) Frame = +2 Query: 251 NGVCQEALTEHGYVCLCAPGF-GGNNCDRIG-ESCRP---GLCGPGKCMNTADSYKCAC- 412 NG C+ + Y CLC PGF +N D + + C +C G C+NTA S+ C C Sbjct: 1858 NGTCKNIIGS--YNCLCFPGFVVTHNGDCVDFDECTTLVGQVCRFGHCLNTAGSFHCLCQ 1915 Query: 413 ---PVTYTGKNC 439 +T GKNC Sbjct: 1916 DGFELTADGKNC 1927 Score = 40.3 bits (90), Expect = 0.004 Identities = 25/71 (35%), Positives = 29/71 (40%), Gaps = 5/71 (7%) Frame = +2 Query: 218 CFTCAPNLCLNNGVCQEALTEHGYVCLCAPGF----GGNNCDRIGESCR-PGLCGPGKCM 382 C T +C G C T + CLC GF G NC E G C PG C Sbjct: 1890 CTTLVGQVC-RFGHCLN--TAGSFHCLCQDGFELTADGKNCVDTNECLSLAGTCLPGTCQ 1946 Query: 383 NTADSYKCACP 415 N S++C CP Sbjct: 1947 NLEGSFRCICP 1957 Score = 40.3 bits (90), Expect = 0.004 Identities = 26/75 (34%), Positives = 33/75 (44%), Gaps = 4/75 (5%) Frame = +2 Query: 200 KENVQNCFTCAPNLCLNNGVCQEALTEHGYVCLCAPG----FGGNNCDRIGESCRPGLCG 367 +E+V C P +C NGVC T+ + C C G F G NC E CG Sbjct: 2082 REDVNECAE-NPGVC-TNGVCVN--TDGSFRCECPFGYSLDFTGINCVDTDECSVGHPCG 2137 Query: 368 PGKCMNTADSYKCAC 412 G C N ++CAC Sbjct: 2138 QGTCTNVIGGFECAC 2152 Score = 39.9 bits (89), Expect = 0.006 Identities = 26/67 (38%), Positives = 29/67 (43%), Gaps = 5/67 (7%) Frame = +2 Query: 227 CAPN-LCLNNGVCQEALTEHGYVCLCAPGF----GGNNCDRIGESCRPGLCGPGKCMNTA 391 CA N L +NG CQ + Y C C PGF C + E C C G C N A Sbjct: 728 CALNSLLCDNGWCQNS--PGSYSCSCPPGFHFWQDTEICKDVDE-CLSSPCVSGVCRNLA 784 Query: 392 DSYKCAC 412 SY C C Sbjct: 785 GSYTCKC 791 Score = 39.9 bits (89), Expect = 0.006 Identities = 18/48 (37%), Positives = 25/48 (52%), Gaps = 6/48 (12%) Frame = +2 Query: 287 YVCLCAPGF-----GGNNCDRIGES-CRPGLCGPGKCMNTADSYKCAC 412 + C+C PG G C E +P LC G+C+NTA S++C C Sbjct: 2232 FACVCPPGMRPLPGSGEGCTDDNECHAQPDLCVNGRCVNTAGSFRCDC 2279 Score = 39.5 bits (88), Expect = 0.007 Identities = 27/80 (33%), Positives = 33/80 (41%), Gaps = 9/80 (11%) Frame = +2 Query: 227 CAPNLCL-NNGVCQEALTEHGYVCLCAPGFGGNN----CDRIGESCRPGLCGPGKCMNTA 391 CA N+ L +NG C A GY C C GF C + E + LC G C N Sbjct: 1366 CAENVDLCDNGQCLNA--PGGYRCECEMGFDPTEDHRACQDVDECAQGNLCAFGSCENLP 1423 Query: 392 DSYKCACPVTYT----GKNC 439 ++C C Y G NC Sbjct: 1424 GMFRCICNGGYELDRGGGNC 1443 Score = 39.5 bits (88), Expect = 0.007 Identities = 22/69 (31%), Positives = 30/69 (43%), Gaps = 4/69 (5%) Frame = +2 Query: 233 PNLCLNNGVCQEALTEHGYVCLCAPGF----GGNNCDRIGESCRPGLCGPGKCMNTADSY 400 P C +G C T + C C GF G+ C+ + E P C G C N Y Sbjct: 2493 PGPCGAHGHCHN--TPGSFRCECHQGFTLVSSGHGCEDVNECDGPHRCQHG-CQNQLGGY 2549 Query: 401 KCACPVTYT 427 +C+CP +T Sbjct: 2550 RCSCPQGFT 2558 Score = 38.3 bits (85), Expect = 0.017 Identities = 22/60 (36%), Positives = 28/60 (46%), Gaps = 9/60 (15%) Frame = +2 Query: 287 YVCLCAPGFGGNN----CDRIGESC-RPGLCGPGKCMNTADSYKCACPVTY----TGKNC 439 Y C C PGF C + E GLC G+C+NT S++C C + GKNC Sbjct: 470 YHCRCYPGFQATPTRQACVDVDECIVSGGLCHLGRCVNTEGSFQCVCNAGFELSPDGKNC 529 Score = 38.3 bits (85), Expect = 0.017 Identities = 23/72 (31%), Positives = 33/72 (45%), Gaps = 5/72 (6%) Frame = +2 Query: 239 LCLNNGVCQ-EALTEHGYVCLCAPGFGGNNCDRIGESCRPGLCGPGKCMNTADSYKCACP 415 LC G + L G+ + P + + E+ PG+C G C+NT S++C CP Sbjct: 2055 LCPQEGSAAFQELCPFGHGAVPGPDDSREDVNECAEN--PGVCTNGVCVNTDGSFRCECP 2112 Query: 416 VTY----TGKNC 439 Y TG NC Sbjct: 2113 FGYSLDFTGINC 2124 Score = 37.1 bits (82), Expect = 0.039 Identities = 25/76 (32%), Positives = 33/76 (43%), Gaps = 5/76 (6%) Frame = +2 Query: 203 ENVQNCFTCAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNN----CDRIGE-SCRPGLCG 367 E+V C P+ C + CQ L GY C C GF ++ C E + P CG Sbjct: 2527 EDVNECD--GPHRCQHG--CQNQLG--GYRCSCPQGFTQHSQWAQCVDENECALSPPTCG 2580 Query: 368 PGKCMNTADSYKCACP 415 C NT ++C CP Sbjct: 2581 SASCRNTLGGFRCVCP 2596 Score = 36.7 bits (81), Expect = 0.052 Identities = 27/84 (32%), Positives = 35/84 (41%), Gaps = 5/84 (5%) Frame = +2 Query: 176 NIMALALEKENVQNCFTCAPNLCLNNGVCQEALTEHGYVCLCAPGFG---GNNCDRIGES 346 N ++ L E+V C + + C N C Y C C G+ G C E Sbjct: 1753 NYNSILLACEDVDECGS-RESPCQQNADCINI--PGSYRCKCTRGYKLSPGGACVGRNE- 1808 Query: 347 CR--PGLCGPGKCMNTADSYKCAC 412 CR P +C G CM+T SY C C Sbjct: 1809 CREIPNVCSHGDCMDTEGSYMCLC 1832 Score = 35.9 bits (79), Expect = 0.090 Identities = 17/50 (34%), Positives = 22/50 (44%), Gaps = 4/50 (8%) Frame = +2 Query: 275 TEHGYVCLCAPGF----GGNNCDRIGESCRPGLCGPGKCMNTADSYKCAC 412 TE + C+C GF G NC E +C G C+N S+ C C Sbjct: 508 TEGSFQCVCNAGFELSPDGKNCVDHNECATSTMCVNGVCLNEDGSFSCLC 557 Score = 35.9 bits (79), Expect = 0.090 Identities = 16/49 (32%), Positives = 23/49 (46%), Gaps = 3/49 (6%) Frame = +2 Query: 287 YVCLCAPGFGGNN--CDRIGESCRP-GLCGPGKCMNTADSYKCACPVTY 424 Y C C GF G+ C+ E LC G+C+N Y+C C + + Sbjct: 1345 YRCTCRQGFAGDGFFCEDRDECAENVDLCDNGQCLNAPGGYRCECEMGF 1393 Score = 35.5 bits (78), Expect = 0.12 Identities = 19/57 (33%), Positives = 26/57 (45%), Gaps = 6/57 (10%) Frame = +2 Query: 287 YVCLCAPGFGGNNCDRIGESCR--PGLCGPGKCMNTADSYKCACPVTY----TGKNC 439 + LC+ G G R C P +C G C N SY+C C + Y +GK+C Sbjct: 666 FQALCSSGLGITTDGRDINECALDPEVCANGVCENLRGSYRCVCNLGYEAGASGKDC 722 Score = 35.1 bits (77), Expect = 0.16 Identities = 16/40 (40%), Positives = 20/40 (50%), Gaps = 2/40 (5%) Frame = +2 Query: 305 PGFGGNNCDRIGESCR--PGLCGPGKCMNTADSYKCACPV 418 P C + E C+ PGLC G C+N S+ C CPV Sbjct: 238 PNIHTGACQDVDE-CQAVPGLCQGGSCVNMVGSFHCRCPV 276 Score = 35.1 bits (77), Expect = 0.16 Identities = 18/49 (36%), Positives = 24/49 (48%), Gaps = 2/49 (4%) Frame = +2 Query: 287 YVCLCAPGFGGNNCDRIGESCR--PGLCGPGKCMNTADSYKCACPVTYT 427 Y LC G G R + CR LC G+C+N+ S++C C YT Sbjct: 2347 YRKLCPHGSGYTAEGRDVDECRMLAHLCAHGECINSLGSFRCHCQAGYT 2395 Score = 34.3 bits (75), Expect = 0.27 Identities = 25/83 (30%), Positives = 36/83 (43%), Gaps = 7/83 (8%) Frame = +2 Query: 233 PNLCLNNGVCQEALTEHGYVCLCAPGF----GGNNCDRIGESCRPG--LCGP-GKCMNTA 391 P++CL+ G C+ T+ +VC C G+ G C + E C G C C+N Sbjct: 1246 PHICLH-GDCEN--TKGSFVCHCQLGYMVRKGATGCSDVDE-CEVGGHNCDSHASCLNIP 1301 Query: 392 DSYKCACPVTYTGKNCEVKQLIE 460 S+ C C + G E L E Sbjct: 1302 GSFSCRCLPGWVGDGFECHDLDE 1324 Score = 34.3 bits (75), Expect = 0.27 Identities = 17/52 (32%), Positives = 25/52 (48%), Gaps = 4/52 (7%) Frame = +2 Query: 287 YVCLCAPGFGGNN--CDRIGESC-RPGLCGP-GKCMNTADSYKCACPVTYTG 430 + C C PG+ G+ C + E + C P G C+N SY+C C + G Sbjct: 1304 FSCRCLPGWVGDGFECHDLDECVSQEHRCSPRGDCLNVPGSYRCTCRQGFAG 1355 Score = 33.9 bits (74), Expect = 0.36 Identities = 22/62 (35%), Positives = 27/62 (43%), Gaps = 3/62 (4%) Frame = +2 Query: 236 NLCLNNGVCQEALTEHGYVCLCAPGFGGN---NCDRIGESCRPGLCGPGKCMNTADSYKC 406 NLCLN G C T Y C C G+ + C + E C C G C+N +Y C Sbjct: 417 NLCLN-GRCLP--TPSSYRCECNVGYTQDVRGECIDVDE-CTSSPCHHGDCVNIPGTYHC 472 Query: 407 AC 412 C Sbjct: 473 RC 474 Score = 33.5 bits (73), Expect = 0.48 Identities = 22/69 (31%), Positives = 29/69 (42%), Gaps = 5/69 (7%) Frame = +2 Query: 233 PNLCLNNGVCQEALTEHGYVCLCAPGFGGN----NCDRIGE-SCRPGLCGPGKCMNTADS 397 P +C + G C G+ CLC GF C + E P +C G C NT S Sbjct: 1204 PRVC-DQGHCTNM--PGGHRCLCYDGFMATPDMRTCVDVDECDLNPHICLHGDCENTKGS 1260 Query: 398 YKCACPVTY 424 + C C + Y Sbjct: 1261 FVCHCQLGY 1269 Score = 32.3 bits (70), Expect = 1.1 Identities = 12/23 (52%), Positives = 15/23 (65%) Frame = +2 Query: 359 LCGPGKCMNTADSYKCACPVTYT 427 LC G+C+ T SY+C C V YT Sbjct: 418 LCLNGRCLPTPSSYRCECNVGYT 440 Score = 31.5 bits (68), Expect = 1.9 Identities = 28/83 (33%), Positives = 34/83 (40%), Gaps = 12/83 (14%) Frame = +2 Query: 233 PNLCLNNGVCQEALTEHGYVCLCAPGF----GGNNC-DRIGESC----RPGLCGPGKCMN 385 PNLCL G C + + CLC PGF G+ C D C G C K N Sbjct: 1977 PNLCLF-GTCTNS--PGSFQCLCPPGFVLSDNGHRCFDTRQSFCFTRFEAGKCSVPKAFN 2033 Query: 386 TADSYKCAC---PVTYTGKNCEV 445 T + +C C P G CE+ Sbjct: 2034 TTKT-RCCCSKRPGEGWGDPCEL 2055 Score = 31.1 bits (67), Expect = 2.6 Identities = 12/32 (37%), Positives = 17/32 (53%) Frame = +2 Query: 329 DRIGESCRPGLCGPGKCMNTADSYKCACPVTY 424 D GE P +C G C+N S++C CP + Sbjct: 1723 DECGEI--PAICANGICINQIGSFRCECPAGF 1752 Score = 30.7 bits (66), Expect = 3.4 Identities = 21/70 (30%), Positives = 30/70 (42%), Gaps = 6/70 (8%) Frame = +2 Query: 233 PNLCLNNGVCQEALTEHGYVCLCAPGFGGNN----CDRIGE-SCRPGLCGPGK-CMNTAD 394 P +C N G+C + + C C GF N+ C+ + E R C C+N Sbjct: 1729 PAICAN-GICINQIGS--FRCECPAGFNYNSILLACEDVDECGSRESPCQQNADCINIPG 1785 Query: 395 SYKCACPVTY 424 SY+C C Y Sbjct: 1786 SYRCKCTRGY 1795 Score = 30.7 bits (66), Expect = 3.4 Identities = 22/76 (28%), Positives = 31/76 (40%), Gaps = 5/76 (6%) Frame = +2 Query: 212 QNCFTCAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNN----CDRIGESC-RPGLCGPGK 376 +N +P C + C+ L G+ C+C GF + C + E R G C Sbjct: 2569 ENECALSPPTC-GSASCRNTLG--GFRCVCPSGFDFDQALGGCQDVDECAGRRGPCSYS- 2624 Query: 377 CMNTADSYKCACPVTY 424 C NT + C CP Y Sbjct: 2625 CANTPGGFLCGCPQGY 2640 Score = 29.5 bits (63), Expect = 7.8 Identities = 25/81 (30%), Positives = 36/81 (44%), Gaps = 6/81 (7%) Frame = +2 Query: 203 ENVQNCFTCAPNLCLNNGVCQEALTEHGYVCLCAPGFGGN----NCDRIGESCRP--GLC 364 E++ C + + LC +G C + + C C GF C I E CR G C Sbjct: 1112 EDIDEC-SLSDGLC-PHGQCVNVIG--AFQCSCHAGFQSTPDRQGCVDINE-CRVQNGGC 1166 Query: 365 GPGKCMNTADSYKCACPVTYT 427 C+NT SY+C+C Y+ Sbjct: 1167 DV-HCINTEGSYRCSCGQGYS 1186 >AB177798-1|BAD16734.1| 2809|Homo sapiens fibrillin 3 protein. Length = 2809 Score = 56.0 bits (129), Expect = 8e-08 Identities = 30/67 (44%), Positives = 36/67 (53%), Gaps = 5/67 (7%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHG-YVCLCAPGF----GGNNCDRIGESCRPGLCGPGKCMNTA 391 CA + NGVC L E G + CLC PGF GG+ C I E PG+C G C NT Sbjct: 535 CATSTMCVNGVC---LNEDGSFSCLCKPGFLLAPGGHYCMDIDECQTPGICVNGHCTNTE 591 Query: 392 DSYKCAC 412 S++C C Sbjct: 592 GSFRCQC 598 Score = 49.6 bits (113), Expect = 7e-06 Identities = 32/103 (31%), Positives = 48/103 (46%), Gaps = 10/103 (9%) Frame = +2 Query: 203 ENVQNCFTCAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNN----CDRIGE-SCRPGLCG 367 E++ C P LC G C T + C C PG+ + C+ I E S +CG Sbjct: 1562 EDIDECQEL-PGLC-QGGDCVN--TFGSFQCECPPGYHLSEHTRICEDIDECSTHSSICG 1617 Query: 368 PGKCMNTADSYKCACPVTYT----GKNC-EVKQLIEYPAFTGS 481 PG C NT +Y C CP Y G NC ++++ + + + G+ Sbjct: 1618 PGTCYNTLGNYTCVCPAEYLQVNGGNNCMDMRKSVCFRHYNGT 1660 Score = 49.2 bits (112), Expect = 9e-06 Identities = 35/98 (35%), Positives = 44/98 (44%), Gaps = 12/98 (12%) Frame = +2 Query: 185 ALALEKENVQNCFTC--APNLCLNNGVCQEALTEHGYVCLCAPGFGGN-----NCDRIGE 343 AL ++ N + C +P+LC G C T + C C PG+ NC + E Sbjct: 1018 ALDAQERNCTDIDECRISPDLC-GQGTCVN--TPGSFECECFPGYESGFMLMKNCMDVDE 1074 Query: 344 SCR-PGLCGPGKCMNTADSYKCACP----VTYTGKNCE 442 R P LC G C NT SYKC CP +T G CE Sbjct: 1075 CARDPLLCRGGTCTNTDGSYKCQCPPGHELTAKGTACE 1112 Score = 48.0 bits (109), Expect = 2e-05 Identities = 28/66 (42%), Positives = 34/66 (51%), Gaps = 6/66 (9%) Frame = +2 Query: 233 PNLCLNNGVCQEALTEHGYVCLCAPGFG----GNNCDRIGESCR--PGLCGPGKCMNTAD 394 P LC +G C+ T + C CA GF NC I E CR P LCG G C+NT Sbjct: 994 PGLC-THGTCRN--TVGSFHCACAGGFALDAQERNCTDIDE-CRISPDLCGQGTCVNTPG 1049 Query: 395 SYKCAC 412 S++C C Sbjct: 1050 SFECEC 1055 Score = 44.8 bits (101), Expect = 2e-04 Identities = 21/44 (47%), Positives = 27/44 (61%), Gaps = 5/44 (11%) Frame = +2 Query: 299 CAPGFG---GNNCDRIGESCR--PGLCGPGKCMNTADSYKCACP 415 CA GF G CD + E C PG+C G+C+NTA S++C CP Sbjct: 855 CARGFARMTGVTCDDVNE-CESFPGVCPNGRCVNTAGSFRCECP 897 Score = 44.8 bits (101), Expect = 2e-04 Identities = 28/73 (38%), Positives = 35/73 (47%), Gaps = 5/73 (6%) Frame = +2 Query: 212 QNCFTCAP-NLCLNNGVCQEALTEHGYVCLCAPGF----GGNNCDRIGESCRPGLCGPGK 376 Q+ CA NLC G C+ + C+C G+ GG NC I E P C G Sbjct: 1403 QDVDECAQGNLCAF-GSCENL--PGMFRCICNGGYELDRGGGNCTDINECADPVNCINGV 1459 Query: 377 CMNTADSYKCACP 415 C+NT SY C+CP Sbjct: 1460 CINTPGSYLCSCP 1472 Score = 44.0 bits (99), Expect = 3e-04 Identities = 26/64 (40%), Positives = 32/64 (50%), Gaps = 4/64 (6%) Frame = +2 Query: 233 PNLCLNNGVCQEALTEHGYVCLCAPGFGGNN----CDRIGESCRPGLCGPGKCMNTADSY 400 PN+C ++G C + TE Y+CLC GF + C I E C CG G C N SY Sbjct: 1813 PNVC-SHGDCMD--TEGSYMCLCHRGFQASADQTLCMDIDE-CDRQPCGNGTCKNIIGSY 1868 Query: 401 KCAC 412 C C Sbjct: 1869 NCLC 1872 Score = 44.0 bits (99), Expect = 3e-04 Identities = 27/73 (36%), Positives = 36/73 (49%), Gaps = 3/73 (4%) Frame = +2 Query: 206 NVQNCFTCAPNLCLNNGVCQEALTEHGYVCLCAPGFG--GNNCDRIGE-SCRPGLCGPGK 376 + C + A CL G CQ E + C+C PGF ++C I E S P LC G Sbjct: 1929 DTNECLSLA-GTCLP-GTCQNL--EGSFRCICPPGFQVQSDHCIDIDECSEEPNLCLFGT 1984 Query: 377 CMNTADSYKCACP 415 C N+ S++C CP Sbjct: 1985 CTNSPGSFQCLCP 1997 Score = 43.6 bits (98), Expect = 4e-04 Identities = 27/77 (35%), Positives = 37/77 (48%), Gaps = 7/77 (9%) Frame = +2 Query: 203 ENVQNCFTCA--PNLCLNNGVCQEALTEHGYVCLCAPGFG----GNNCDRIGE-SCRPGL 361 +N + CA P LC G C T+ Y C C PG G C+ I E S GL Sbjct: 1067 KNCMDVDECARDPLLC-RGGTCTN--TDGSYKCQCPPGHELTAKGTACEDIDECSLSDGL 1123 Query: 362 CGPGKCMNTADSYKCAC 412 C G+C+N +++C+C Sbjct: 1124 CPHGQCVNVIGAFQCSC 1140 Score = 42.7 bits (96), Expect = 8e-04 Identities = 24/83 (28%), Positives = 37/83 (44%), Gaps = 5/83 (6%) Frame = +2 Query: 182 MALALEKENVQNCFTCAPNLCLNNGVCQEALTEHGYVCLCAPGF----GGNNCDRIGESC 349 + + + ++ C P +C N GVC+ Y C+C G+ G +C + E Sbjct: 674 LGITTDGRDINEC-ALDPEVCAN-GVCENL--RGSYRCVCNLGYEAGASGKDCTDVDECA 729 Query: 350 RPGL-CGPGKCMNTADSYKCACP 415 L C G C N+ SY C+CP Sbjct: 730 LNSLLCDNGWCQNSPGSYSCSCP 752 Score = 42.3 bits (95), Expect = 0.001 Identities = 26/71 (36%), Positives = 31/71 (43%), Gaps = 4/71 (5%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGN---NCDRIGE-SCRPGLCGPGKCMNTAD 394 C+ G C + G+ C CA GF C+ I E S P LC +C NT Sbjct: 2130 CSVGHPCGQGTCTNVIG--GFECACADGFEPGLMMTCEDIDECSLNPLLCA-FRCHNTEG 2186 Query: 395 SYKCACPVTYT 427 SY C CP YT Sbjct: 2187 SYLCTCPAGYT 2197 Score = 41.5 bits (93), Expect = 0.002 Identities = 27/72 (37%), Positives = 36/72 (50%), Gaps = 9/72 (12%) Frame = +2 Query: 251 NGVCQEALTEHGYVCLCAPGF-GGNNCDRIG-ESCRP---GLCGPGKCMNTADSYKCAC- 412 NG C+ + Y CLC PGF +N D + + C +C G C+NTA S+ C C Sbjct: 1858 NGTCKNIIGS--YNCLCFPGFVVTHNGDCVDFDECTTLVGQVCRFGHCLNTAGSFHCLCQ 1915 Query: 413 ---PVTYTGKNC 439 +T GKNC Sbjct: 1916 DGFELTADGKNC 1927 Score = 40.3 bits (90), Expect = 0.004 Identities = 25/71 (35%), Positives = 29/71 (40%), Gaps = 5/71 (7%) Frame = +2 Query: 218 CFTCAPNLCLNNGVCQEALTEHGYVCLCAPGF----GGNNCDRIGESCR-PGLCGPGKCM 382 C T +C G C T + CLC GF G NC E G C PG C Sbjct: 1890 CTTLVGQVC-RFGHCLN--TAGSFHCLCQDGFELTADGKNCVDTNECLSLAGTCLPGTCQ 1946 Query: 383 NTADSYKCACP 415 N S++C CP Sbjct: 1947 NLEGSFRCICP 1957 Score = 40.3 bits (90), Expect = 0.004 Identities = 26/75 (34%), Positives = 33/75 (44%), Gaps = 4/75 (5%) Frame = +2 Query: 200 KENVQNCFTCAPNLCLNNGVCQEALTEHGYVCLCAPG----FGGNNCDRIGESCRPGLCG 367 +E+V C P +C NGVC T+ + C C G F G NC E CG Sbjct: 2082 REDVNECAE-NPGVC-TNGVCVN--TDGSFRCECPFGYSLDFTGINCVDTDECSVGHPCG 2137 Query: 368 PGKCMNTADSYKCAC 412 G C N ++CAC Sbjct: 2138 QGTCTNVIGGFECAC 2152 Score = 39.9 bits (89), Expect = 0.006 Identities = 26/67 (38%), Positives = 29/67 (43%), Gaps = 5/67 (7%) Frame = +2 Query: 227 CAPN-LCLNNGVCQEALTEHGYVCLCAPGF----GGNNCDRIGESCRPGLCGPGKCMNTA 391 CA N L +NG CQ + Y C C PGF C + E C C G C N A Sbjct: 728 CALNSLLCDNGWCQNS--PGSYSCSCPPGFHFWQDTEICKDVDE-CLSSPCVSGVCRNLA 784 Query: 392 DSYKCAC 412 SY C C Sbjct: 785 GSYTCKC 791 Score = 39.9 bits (89), Expect = 0.006 Identities = 18/48 (37%), Positives = 25/48 (52%), Gaps = 6/48 (12%) Frame = +2 Query: 287 YVCLCAPGF-----GGNNCDRIGES-CRPGLCGPGKCMNTADSYKCAC 412 + C+C PG G C E +P LC G+C+NTA S++C C Sbjct: 2232 FACVCPPGMRPLPGSGEGCTDDNECHAQPDLCVNGRCVNTAGSFRCDC 2279 Score = 39.5 bits (88), Expect = 0.007 Identities = 27/80 (33%), Positives = 33/80 (41%), Gaps = 9/80 (11%) Frame = +2 Query: 227 CAPNLCL-NNGVCQEALTEHGYVCLCAPGFGGNN----CDRIGESCRPGLCGPGKCMNTA 391 CA N+ L +NG C A GY C C GF C + E + LC G C N Sbjct: 1366 CAENVDLCDNGQCLNA--PGGYRCECEMGFDPTEDHRACQDVDECAQGNLCAFGSCENLP 1423 Query: 392 DSYKCACPVTYT----GKNC 439 ++C C Y G NC Sbjct: 1424 GMFRCICNGGYELDRGGGNC 1443 Score = 39.5 bits (88), Expect = 0.007 Identities = 22/69 (31%), Positives = 30/69 (43%), Gaps = 4/69 (5%) Frame = +2 Query: 233 PNLCLNNGVCQEALTEHGYVCLCAPGF----GGNNCDRIGESCRPGLCGPGKCMNTADSY 400 P C +G C T + C C GF G+ C+ + E P C G C N Y Sbjct: 2493 PGPCGAHGHCHN--TPGSFRCECHQGFTLVSSGHGCEDVNECDGPHRCQHG-CQNQLGGY 2549 Query: 401 KCACPVTYT 427 +C+CP +T Sbjct: 2550 RCSCPQGFT 2558 Score = 38.3 bits (85), Expect = 0.017 Identities = 22/60 (36%), Positives = 28/60 (46%), Gaps = 9/60 (15%) Frame = +2 Query: 287 YVCLCAPGFGGNN----CDRIGESC-RPGLCGPGKCMNTADSYKCACPVTY----TGKNC 439 Y C C PGF C + E GLC G+C+NT S++C C + GKNC Sbjct: 470 YHCRCYPGFQATPTRQACVDVDECIVSGGLCHLGRCVNTEGSFQCVCNAGFELSPDGKNC 529 Score = 38.3 bits (85), Expect = 0.017 Identities = 23/72 (31%), Positives = 33/72 (45%), Gaps = 5/72 (6%) Frame = +2 Query: 239 LCLNNGVCQ-EALTEHGYVCLCAPGFGGNNCDRIGESCRPGLCGPGKCMNTADSYKCACP 415 LC G + L G+ + P + + E+ PG+C G C+NT S++C CP Sbjct: 2055 LCPQEGSAAFQELCPFGHGAVPGPDDSREDVNECAEN--PGVCTNGVCVNTDGSFRCECP 2112 Query: 416 VTY----TGKNC 439 Y TG NC Sbjct: 2113 FGYSLDFTGINC 2124 Score = 37.1 bits (82), Expect = 0.039 Identities = 25/76 (32%), Positives = 33/76 (43%), Gaps = 5/76 (6%) Frame = +2 Query: 203 ENVQNCFTCAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNN----CDRIGE-SCRPGLCG 367 E+V C P+ C + CQ L GY C C GF ++ C E + P CG Sbjct: 2527 EDVNECD--GPHRCQHG--CQNQLG--GYRCSCPQGFTQHSQWAQCVDENECALSPPTCG 2580 Query: 368 PGKCMNTADSYKCACP 415 C NT ++C CP Sbjct: 2581 SASCRNTLGGFRCVCP 2596 Score = 36.7 bits (81), Expect = 0.052 Identities = 27/84 (32%), Positives = 35/84 (41%), Gaps = 5/84 (5%) Frame = +2 Query: 176 NIMALALEKENVQNCFTCAPNLCLNNGVCQEALTEHGYVCLCAPGFG---GNNCDRIGES 346 N ++ L E+V C + + C N C Y C C G+ G C E Sbjct: 1753 NYNSILLACEDVDECGS-RESPCQQNADCINI--PGSYRCKCTRGYKLSPGGACVGRNE- 1808 Query: 347 CR--PGLCGPGKCMNTADSYKCAC 412 CR P +C G CM+T SY C C Sbjct: 1809 CREIPNVCSHGDCMDTEGSYMCLC 1832 Score = 35.9 bits (79), Expect = 0.090 Identities = 17/50 (34%), Positives = 22/50 (44%), Gaps = 4/50 (8%) Frame = +2 Query: 275 TEHGYVCLCAPGF----GGNNCDRIGESCRPGLCGPGKCMNTADSYKCAC 412 TE + C+C GF G NC E +C G C+N S+ C C Sbjct: 508 TEGSFQCVCNAGFELSPDGKNCVDHNECATSTMCVNGVCLNEDGSFSCLC 557 Score = 35.9 bits (79), Expect = 0.090 Identities = 16/49 (32%), Positives = 23/49 (46%), Gaps = 3/49 (6%) Frame = +2 Query: 287 YVCLCAPGFGGNN--CDRIGESCRP-GLCGPGKCMNTADSYKCACPVTY 424 Y C C GF G+ C+ E LC G+C+N Y+C C + + Sbjct: 1345 YRCTCRQGFAGDGFFCEDRDECAENVDLCDNGQCLNAPGGYRCECEMGF 1393 Score = 35.5 bits (78), Expect = 0.12 Identities = 19/57 (33%), Positives = 26/57 (45%), Gaps = 6/57 (10%) Frame = +2 Query: 287 YVCLCAPGFGGNNCDRIGESCR--PGLCGPGKCMNTADSYKCACPVTY----TGKNC 439 + LC+ G G R C P +C G C N SY+C C + Y +GK+C Sbjct: 666 FQALCSSGLGITTDGRDINECALDPEVCANGVCENLRGSYRCVCNLGYEAGASGKDC 722 Score = 35.1 bits (77), Expect = 0.16 Identities = 16/40 (40%), Positives = 20/40 (50%), Gaps = 2/40 (5%) Frame = +2 Query: 305 PGFGGNNCDRIGESCR--PGLCGPGKCMNTADSYKCACPV 418 P C + E C+ PGLC G C+N S+ C CPV Sbjct: 238 PNIHTGACQDVDE-CQAVPGLCQGGSCVNMVGSFHCRCPV 276 Score = 35.1 bits (77), Expect = 0.16 Identities = 18/49 (36%), Positives = 24/49 (48%), Gaps = 2/49 (4%) Frame = +2 Query: 287 YVCLCAPGFGGNNCDRIGESCR--PGLCGPGKCMNTADSYKCACPVTYT 427 Y LC G G R + CR LC G+C+N+ S++C C YT Sbjct: 2347 YRKLCPHGSGYTAEGRDVDECRMLAHLCAHGECINSLGSFRCHCQAGYT 2395 Score = 34.3 bits (75), Expect = 0.27 Identities = 25/83 (30%), Positives = 36/83 (43%), Gaps = 7/83 (8%) Frame = +2 Query: 233 PNLCLNNGVCQEALTEHGYVCLCAPGF----GGNNCDRIGESCRPG--LCGP-GKCMNTA 391 P++CL+ G C+ T+ +VC C G+ G C + E C G C C+N Sbjct: 1246 PHICLH-GDCEN--TKGSFVCHCQLGYMVRKGATGCSDVDE-CEVGGHNCDSHASCLNIP 1301 Query: 392 DSYKCACPVTYTGKNCEVKQLIE 460 S+ C C + G E L E Sbjct: 1302 GSFSCRCLPGWVGDGFECHDLDE 1324 Score = 34.3 bits (75), Expect = 0.27 Identities = 17/52 (32%), Positives = 25/52 (48%), Gaps = 4/52 (7%) Frame = +2 Query: 287 YVCLCAPGFGGNN--CDRIGESC-RPGLCGP-GKCMNTADSYKCACPVTYTG 430 + C C PG+ G+ C + E + C P G C+N SY+C C + G Sbjct: 1304 FSCRCLPGWVGDGFECHDLDECVSQEHRCSPRGDCLNVPGSYRCTCRQGFAG 1355 Score = 33.9 bits (74), Expect = 0.36 Identities = 22/62 (35%), Positives = 27/62 (43%), Gaps = 3/62 (4%) Frame = +2 Query: 236 NLCLNNGVCQEALTEHGYVCLCAPGFGGN---NCDRIGESCRPGLCGPGKCMNTADSYKC 406 NLCLN G C T Y C C G+ + C + E C C G C+N +Y C Sbjct: 417 NLCLN-GRCLP--TPSSYRCECNVGYTQDVRGECIDVDE-CTSSPCHHGDCVNIPGTYHC 472 Query: 407 AC 412 C Sbjct: 473 RC 474 Score = 33.5 bits (73), Expect = 0.48 Identities = 22/69 (31%), Positives = 29/69 (42%), Gaps = 5/69 (7%) Frame = +2 Query: 233 PNLCLNNGVCQEALTEHGYVCLCAPGFGGN----NCDRIGE-SCRPGLCGPGKCMNTADS 397 P +C + G C G+ CLC GF C + E P +C G C NT S Sbjct: 1204 PRVC-DQGHCTNM--PGGHRCLCYDGFMATPDMRTCVDVDECDLNPHICLHGDCENTKGS 1260 Query: 398 YKCACPVTY 424 + C C + Y Sbjct: 1261 FVCHCQLGY 1269 Score = 32.3 bits (70), Expect = 1.1 Identities = 12/23 (52%), Positives = 15/23 (65%) Frame = +2 Query: 359 LCGPGKCMNTADSYKCACPVTYT 427 LC G+C+ T SY+C C V YT Sbjct: 418 LCLNGRCLPTPSSYRCECNVGYT 440 Score = 31.5 bits (68), Expect = 1.9 Identities = 28/83 (33%), Positives = 34/83 (40%), Gaps = 12/83 (14%) Frame = +2 Query: 233 PNLCLNNGVCQEALTEHGYVCLCAPGF----GGNNC-DRIGESC----RPGLCGPGKCMN 385 PNLCL G C + + CLC PGF G+ C D C G C K N Sbjct: 1977 PNLCLF-GTCTNS--PGSFQCLCPPGFVLSDNGHRCFDTRQSFCFTRFEAGKCSVPKAFN 2033 Query: 386 TADSYKCAC---PVTYTGKNCEV 445 T + +C C P G CE+ Sbjct: 2034 TTKT-RCCCSKRPGEGWGDPCEL 2055 Score = 31.1 bits (67), Expect = 2.6 Identities = 12/32 (37%), Positives = 17/32 (53%) Frame = +2 Query: 329 DRIGESCRPGLCGPGKCMNTADSYKCACPVTY 424 D GE P +C G C+N S++C CP + Sbjct: 1723 DECGEI--PAICANGICINQIGSFRCECPAGF 1752 Score = 30.7 bits (66), Expect = 3.4 Identities = 21/70 (30%), Positives = 30/70 (42%), Gaps = 6/70 (8%) Frame = +2 Query: 233 PNLCLNNGVCQEALTEHGYVCLCAPGFGGNN----CDRIGE-SCRPGLCGPGK-CMNTAD 394 P +C N G+C + + C C GF N+ C+ + E R C C+N Sbjct: 1729 PAICAN-GICINQIGS--FRCECPAGFNYNSILLACEDVDECGSRESPCQQNADCINIPG 1785 Query: 395 SYKCACPVTY 424 SY+C C Y Sbjct: 1786 SYRCKCTRGY 1795 Score = 30.7 bits (66), Expect = 3.4 Identities = 22/76 (28%), Positives = 31/76 (40%), Gaps = 5/76 (6%) Frame = +2 Query: 212 QNCFTCAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNN----CDRIGESC-RPGLCGPGK 376 +N +P C + C+ L G+ C+C GF + C + E R G C Sbjct: 2569 ENECALSPPTC-GSASCRNTLG--GFRCVCPSGFDFDQALGGCQDVDECAGRRGPCSYS- 2624 Query: 377 CMNTADSYKCACPVTY 424 C NT + C CP Y Sbjct: 2625 CANTPGGFLCGCPQGY 2640 Score = 29.5 bits (63), Expect = 7.8 Identities = 25/81 (30%), Positives = 36/81 (44%), Gaps = 6/81 (7%) Frame = +2 Query: 203 ENVQNCFTCAPNLCLNNGVCQEALTEHGYVCLCAPGFGGN----NCDRIGESCRP--GLC 364 E++ C + + LC +G C + + C C GF C I E CR G C Sbjct: 1112 EDIDEC-SLSDGLC-PHGQCVNVIG--AFQCSCHAGFQSTPDRQGCVDINE-CRVQNGGC 1166 Query: 365 GPGKCMNTADSYKCACPVTYT 427 C+NT SY+C+C Y+ Sbjct: 1167 DV-HCINTEGSYRCSCGQGYS 1186 >AB177797-1|BAD16733.1| 2809|Homo sapiens fibrillin 3 protein. Length = 2809 Score = 56.0 bits (129), Expect = 8e-08 Identities = 30/67 (44%), Positives = 36/67 (53%), Gaps = 5/67 (7%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHG-YVCLCAPGF----GGNNCDRIGESCRPGLCGPGKCMNTA 391 CA + NGVC L E G + CLC PGF GG+ C I E PG+C G C NT Sbjct: 535 CATSTMCVNGVC---LNEDGSFSCLCKPGFLLAPGGHYCMDIDECQTPGICVNGHCTNTE 591 Query: 392 DSYKCAC 412 S++C C Sbjct: 592 GSFRCQC 598 Score = 49.6 bits (113), Expect = 7e-06 Identities = 32/103 (31%), Positives = 48/103 (46%), Gaps = 10/103 (9%) Frame = +2 Query: 203 ENVQNCFTCAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNN----CDRIGE-SCRPGLCG 367 E++ C P LC G C T + C C PG+ + C+ I E S +CG Sbjct: 1562 EDIDECQEL-PGLC-QGGDCVN--TFGSFQCECPPGYHLSEHTRICEDIDECSTHSSICG 1617 Query: 368 PGKCMNTADSYKCACPVTYT----GKNC-EVKQLIEYPAFTGS 481 PG C NT +Y C CP Y G NC ++++ + + + G+ Sbjct: 1618 PGTCYNTLGNYTCVCPAEYLQVNGGNNCMDMRKSVCFRHYNGT 1660 Score = 49.2 bits (112), Expect = 9e-06 Identities = 35/98 (35%), Positives = 44/98 (44%), Gaps = 12/98 (12%) Frame = +2 Query: 185 ALALEKENVQNCFTC--APNLCLNNGVCQEALTEHGYVCLCAPGFGGN-----NCDRIGE 343 AL ++ N + C +P+LC G C T + C C PG+ NC + E Sbjct: 1018 ALDAQERNCTDIDECRISPDLC-GQGTCVN--TPGSFECECFPGYESGFMLMKNCMDVDE 1074 Query: 344 SCR-PGLCGPGKCMNTADSYKCACP----VTYTGKNCE 442 R P LC G C NT SYKC CP +T G CE Sbjct: 1075 CARDPLLCRGGTCTNTDGSYKCQCPPGHELTAKGTACE 1112 Score = 48.0 bits (109), Expect = 2e-05 Identities = 28/66 (42%), Positives = 34/66 (51%), Gaps = 6/66 (9%) Frame = +2 Query: 233 PNLCLNNGVCQEALTEHGYVCLCAPGFG----GNNCDRIGESCR--PGLCGPGKCMNTAD 394 P LC +G C+ T + C CA GF NC I E CR P LCG G C+NT Sbjct: 994 PGLC-THGTCRN--TVGSFHCACAGGFALDAQERNCTDIDE-CRISPDLCGQGTCVNTPG 1049 Query: 395 SYKCAC 412 S++C C Sbjct: 1050 SFECEC 1055 Score = 44.8 bits (101), Expect = 2e-04 Identities = 21/44 (47%), Positives = 27/44 (61%), Gaps = 5/44 (11%) Frame = +2 Query: 299 CAPGFG---GNNCDRIGESCR--PGLCGPGKCMNTADSYKCACP 415 CA GF G CD + E C PG+C G+C+NTA S++C CP Sbjct: 855 CARGFARMTGVTCDDVNE-CESFPGVCPNGRCVNTAGSFRCECP 897 Score = 44.8 bits (101), Expect = 2e-04 Identities = 28/73 (38%), Positives = 35/73 (47%), Gaps = 5/73 (6%) Frame = +2 Query: 212 QNCFTCAP-NLCLNNGVCQEALTEHGYVCLCAPGF----GGNNCDRIGESCRPGLCGPGK 376 Q+ CA NLC G C+ + C+C G+ GG NC I E P C G Sbjct: 1403 QDVDECAQGNLCAF-GSCENL--PGMFRCICNGGYELDRGGGNCTDINECADPVNCINGV 1459 Query: 377 CMNTADSYKCACP 415 C+NT SY C+CP Sbjct: 1460 CINTPGSYLCSCP 1472 Score = 44.0 bits (99), Expect = 3e-04 Identities = 26/64 (40%), Positives = 32/64 (50%), Gaps = 4/64 (6%) Frame = +2 Query: 233 PNLCLNNGVCQEALTEHGYVCLCAPGFGGNN----CDRIGESCRPGLCGPGKCMNTADSY 400 PN+C ++G C + TE Y+CLC GF + C I E C CG G C N SY Sbjct: 1813 PNVC-SHGDCMD--TEGSYMCLCHRGFQASADQTLCMDIDE-CDRQPCGNGTCKNIIGSY 1868 Query: 401 KCAC 412 C C Sbjct: 1869 NCLC 1872 Score = 44.0 bits (99), Expect = 3e-04 Identities = 27/73 (36%), Positives = 36/73 (49%), Gaps = 3/73 (4%) Frame = +2 Query: 206 NVQNCFTCAPNLCLNNGVCQEALTEHGYVCLCAPGFG--GNNCDRIGE-SCRPGLCGPGK 376 + C + A CL G CQ E + C+C PGF ++C I E S P LC G Sbjct: 1929 DTNECLSLA-GTCLP-GTCQNL--EGSFRCICPPGFQVQSDHCIDIDECSEEPNLCLFGT 1984 Query: 377 CMNTADSYKCACP 415 C N+ S++C CP Sbjct: 1985 CTNSPGSFQCLCP 1997 Score = 43.6 bits (98), Expect = 4e-04 Identities = 27/77 (35%), Positives = 37/77 (48%), Gaps = 7/77 (9%) Frame = +2 Query: 203 ENVQNCFTCA--PNLCLNNGVCQEALTEHGYVCLCAPGFG----GNNCDRIGE-SCRPGL 361 +N + CA P LC G C T+ Y C C PG G C+ I E S GL Sbjct: 1067 KNCMDVDECARDPLLC-RGGTCTN--TDGSYKCQCPPGHELTAKGTACEDIDECSLSDGL 1123 Query: 362 CGPGKCMNTADSYKCAC 412 C G+C+N +++C+C Sbjct: 1124 CPHGQCVNVIGAFQCSC 1140 Score = 42.7 bits (96), Expect = 8e-04 Identities = 24/83 (28%), Positives = 37/83 (44%), Gaps = 5/83 (6%) Frame = +2 Query: 182 MALALEKENVQNCFTCAPNLCLNNGVCQEALTEHGYVCLCAPGF----GGNNCDRIGESC 349 + + + ++ C P +C N GVC+ Y C+C G+ G +C + E Sbjct: 674 LGITTDGRDINEC-ALDPEVCAN-GVCENL--RGSYRCVCNLGYEAGASGKDCTDVDECA 729 Query: 350 RPGL-CGPGKCMNTADSYKCACP 415 L C G C N+ SY C+CP Sbjct: 730 LNSLLCDNGWCQNSPGSYSCSCP 752 Score = 42.3 bits (95), Expect = 0.001 Identities = 26/71 (36%), Positives = 31/71 (43%), Gaps = 4/71 (5%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGN---NCDRIGE-SCRPGLCGPGKCMNTAD 394 C+ G C + G+ C CA GF C+ I E S P LC +C NT Sbjct: 2130 CSVGHPCGQGTCTNVIG--GFECACADGFEPGLMMTCEDIDECSLNPLLCA-FRCHNTEG 2186 Query: 395 SYKCACPVTYT 427 SY C CP YT Sbjct: 2187 SYLCTCPAGYT 2197 Score = 41.5 bits (93), Expect = 0.002 Identities = 27/72 (37%), Positives = 36/72 (50%), Gaps = 9/72 (12%) Frame = +2 Query: 251 NGVCQEALTEHGYVCLCAPGF-GGNNCDRIG-ESCRP---GLCGPGKCMNTADSYKCAC- 412 NG C+ + Y CLC PGF +N D + + C +C G C+NTA S+ C C Sbjct: 1858 NGTCKNIIGS--YNCLCFPGFVVTHNGDCVDFDECTTLVGQVCRFGHCLNTAGSFHCLCQ 1915 Query: 413 ---PVTYTGKNC 439 +T GKNC Sbjct: 1916 DGFELTADGKNC 1927 Score = 40.3 bits (90), Expect = 0.004 Identities = 25/71 (35%), Positives = 29/71 (40%), Gaps = 5/71 (7%) Frame = +2 Query: 218 CFTCAPNLCLNNGVCQEALTEHGYVCLCAPGF----GGNNCDRIGESCR-PGLCGPGKCM 382 C T +C G C T + CLC GF G NC E G C PG C Sbjct: 1890 CTTLVGQVC-RFGHCLN--TAGSFHCLCQDGFELTADGKNCVDTNECLSLAGTCLPGTCQ 1946 Query: 383 NTADSYKCACP 415 N S++C CP Sbjct: 1947 NLEGSFRCICP 1957 Score = 40.3 bits (90), Expect = 0.004 Identities = 26/75 (34%), Positives = 33/75 (44%), Gaps = 4/75 (5%) Frame = +2 Query: 200 KENVQNCFTCAPNLCLNNGVCQEALTEHGYVCLCAPG----FGGNNCDRIGESCRPGLCG 367 +E+V C P +C NGVC T+ + C C G F G NC E CG Sbjct: 2082 REDVNECAE-NPGVC-TNGVCVN--TDGSFRCECPFGYSLDFTGINCVDTDECSVGHPCG 2137 Query: 368 PGKCMNTADSYKCAC 412 G C N ++CAC Sbjct: 2138 QGTCTNVIGGFECAC 2152 Score = 39.9 bits (89), Expect = 0.006 Identities = 26/67 (38%), Positives = 29/67 (43%), Gaps = 5/67 (7%) Frame = +2 Query: 227 CAPN-LCLNNGVCQEALTEHGYVCLCAPGF----GGNNCDRIGESCRPGLCGPGKCMNTA 391 CA N L +NG CQ + Y C C PGF C + E C C G C N A Sbjct: 728 CALNSLLCDNGWCQNS--PGSYSCSCPPGFHFWQDTEICKDVDE-CLSSPCVSGVCRNLA 784 Query: 392 DSYKCAC 412 SY C C Sbjct: 785 GSYTCKC 791 Score = 39.9 bits (89), Expect = 0.006 Identities = 18/48 (37%), Positives = 25/48 (52%), Gaps = 6/48 (12%) Frame = +2 Query: 287 YVCLCAPGF-----GGNNCDRIGES-CRPGLCGPGKCMNTADSYKCAC 412 + C+C PG G C E +P LC G+C+NTA S++C C Sbjct: 2232 FACVCPPGMRPLPGSGEGCTDDNECHAQPDLCVNGRCVNTAGSFRCDC 2279 Score = 39.5 bits (88), Expect = 0.007 Identities = 27/80 (33%), Positives = 33/80 (41%), Gaps = 9/80 (11%) Frame = +2 Query: 227 CAPNLCL-NNGVCQEALTEHGYVCLCAPGFGGNN----CDRIGESCRPGLCGPGKCMNTA 391 CA N+ L +NG C A GY C C GF C + E + LC G C N Sbjct: 1366 CAENVDLCDNGQCLNA--PGGYRCECEMGFDPTEDHRACQDVDECAQGNLCAFGSCENLP 1423 Query: 392 DSYKCACPVTYT----GKNC 439 ++C C Y G NC Sbjct: 1424 GMFRCICNGGYELDRGGGNC 1443 Score = 39.5 bits (88), Expect = 0.007 Identities = 22/69 (31%), Positives = 30/69 (43%), Gaps = 4/69 (5%) Frame = +2 Query: 233 PNLCLNNGVCQEALTEHGYVCLCAPGF----GGNNCDRIGESCRPGLCGPGKCMNTADSY 400 P C +G C T + C C GF G+ C+ + E P C G C N Y Sbjct: 2493 PGPCGAHGHCHN--TPGSFRCECHQGFTLVSSGHGCEDVNECDGPHRCQHG-CQNQLGGY 2549 Query: 401 KCACPVTYT 427 +C+CP +T Sbjct: 2550 RCSCPQGFT 2558 Score = 38.3 bits (85), Expect = 0.017 Identities = 22/60 (36%), Positives = 28/60 (46%), Gaps = 9/60 (15%) Frame = +2 Query: 287 YVCLCAPGFGGNN----CDRIGESC-RPGLCGPGKCMNTADSYKCACPVTY----TGKNC 439 Y C C PGF C + E GLC G+C+NT S++C C + GKNC Sbjct: 470 YHCQCYPGFQATPTRQACVDVDECIVSGGLCHLGRCVNTEGSFQCVCNAGFELSPDGKNC 529 Score = 38.3 bits (85), Expect = 0.017 Identities = 23/72 (31%), Positives = 33/72 (45%), Gaps = 5/72 (6%) Frame = +2 Query: 239 LCLNNGVCQ-EALTEHGYVCLCAPGFGGNNCDRIGESCRPGLCGPGKCMNTADSYKCACP 415 LC G + L G+ + P + + E+ PG+C G C+NT S++C CP Sbjct: 2055 LCPQEGSAAFQELCPFGHGAVPGPDDSREDVNECAEN--PGVCTNGVCVNTDGSFRCECP 2112 Query: 416 VTY----TGKNC 439 Y TG NC Sbjct: 2113 FGYSLDFTGINC 2124 Score = 37.1 bits (82), Expect = 0.039 Identities = 25/76 (32%), Positives = 33/76 (43%), Gaps = 5/76 (6%) Frame = +2 Query: 203 ENVQNCFTCAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNN----CDRIGE-SCRPGLCG 367 E+V C P+ C + CQ L GY C C GF ++ C E + P CG Sbjct: 2527 EDVNECD--GPHRCQHG--CQNQLG--GYRCSCPQGFTQHSQWAQCVDENECALSPPTCG 2580 Query: 368 PGKCMNTADSYKCACP 415 C NT ++C CP Sbjct: 2581 SASCRNTLGGFRCVCP 2596 Score = 36.7 bits (81), Expect = 0.052 Identities = 27/84 (32%), Positives = 35/84 (41%), Gaps = 5/84 (5%) Frame = +2 Query: 176 NIMALALEKENVQNCFTCAPNLCLNNGVCQEALTEHGYVCLCAPGFG---GNNCDRIGES 346 N ++ L E+V C + + C N C Y C C G+ G C E Sbjct: 1753 NYNSILLACEDVDECGS-RESPCQQNADCINI--PGSYRCKCTRGYKLSPGGACVGRNE- 1808 Query: 347 CR--PGLCGPGKCMNTADSYKCAC 412 CR P +C G CM+T SY C C Sbjct: 1809 CREIPNVCSHGDCMDTEGSYMCLC 1832 Score = 35.9 bits (79), Expect = 0.090 Identities = 17/50 (34%), Positives = 22/50 (44%), Gaps = 4/50 (8%) Frame = +2 Query: 275 TEHGYVCLCAPGF----GGNNCDRIGESCRPGLCGPGKCMNTADSYKCAC 412 TE + C+C GF G NC E +C G C+N S+ C C Sbjct: 508 TEGSFQCVCNAGFELSPDGKNCVDHNECATSTMCVNGVCLNEDGSFSCLC 557 Score = 35.9 bits (79), Expect = 0.090 Identities = 16/49 (32%), Positives = 23/49 (46%), Gaps = 3/49 (6%) Frame = +2 Query: 287 YVCLCAPGFGGNN--CDRIGESCRP-GLCGPGKCMNTADSYKCACPVTY 424 Y C C GF G+ C+ E LC G+C+N Y+C C + + Sbjct: 1345 YRCTCRQGFAGDGFFCEDRDECAENVDLCDNGQCLNAPGGYRCECEMGF 1393 Score = 35.5 bits (78), Expect = 0.12 Identities = 19/57 (33%), Positives = 26/57 (45%), Gaps = 6/57 (10%) Frame = +2 Query: 287 YVCLCAPGFGGNNCDRIGESCR--PGLCGPGKCMNTADSYKCACPVTY----TGKNC 439 + LC+ G G R C P +C G C N SY+C C + Y +GK+C Sbjct: 666 FQALCSSGLGITTDGRDINECALDPEVCANGVCENLRGSYRCVCNLGYEAGASGKDC 722 Score = 35.1 bits (77), Expect = 0.16 Identities = 16/40 (40%), Positives = 20/40 (50%), Gaps = 2/40 (5%) Frame = +2 Query: 305 PGFGGNNCDRIGESCR--PGLCGPGKCMNTADSYKCACPV 418 P C + E C+ PGLC G C+N S+ C CPV Sbjct: 238 PNIHTGACQDVDE-CQAVPGLCQGGSCVNMVGSFHCRCPV 276 Score = 35.1 bits (77), Expect = 0.16 Identities = 18/49 (36%), Positives = 24/49 (48%), Gaps = 2/49 (4%) Frame = +2 Query: 287 YVCLCAPGFGGNNCDRIGESCR--PGLCGPGKCMNTADSYKCACPVTYT 427 Y LC G G R + CR LC G+C+N+ S++C C YT Sbjct: 2347 YRKLCPHGSGYTAEGRDVDECRMLAHLCAHGECINSLGSFRCHCQAGYT 2395 Score = 34.3 bits (75), Expect = 0.27 Identities = 25/83 (30%), Positives = 36/83 (43%), Gaps = 7/83 (8%) Frame = +2 Query: 233 PNLCLNNGVCQEALTEHGYVCLCAPGF----GGNNCDRIGESCRPG--LCGP-GKCMNTA 391 P++CL+ G C+ T+ +VC C G+ G C + E C G C C+N Sbjct: 1246 PHICLH-GDCEN--TKGSFVCHCQLGYMVRKGATGCSDVDE-CEVGGHNCDSHASCLNIP 1301 Query: 392 DSYKCACPVTYTGKNCEVKQLIE 460 S+ C C + G E L E Sbjct: 1302 GSFSCRCLPGWVGDGFECHDLDE 1324 Score = 34.3 bits (75), Expect = 0.27 Identities = 17/52 (32%), Positives = 25/52 (48%), Gaps = 4/52 (7%) Frame = +2 Query: 287 YVCLCAPGFGGNN--CDRIGESC-RPGLCGP-GKCMNTADSYKCACPVTYTG 430 + C C PG+ G+ C + E + C P G C+N SY+C C + G Sbjct: 1304 FSCRCLPGWVGDGFECHDLDECVSQEHRCSPRGDCLNVPGSYRCTCRQGFAG 1355 Score = 33.9 bits (74), Expect = 0.36 Identities = 22/62 (35%), Positives = 27/62 (43%), Gaps = 3/62 (4%) Frame = +2 Query: 236 NLCLNNGVCQEALTEHGYVCLCAPGFGGN---NCDRIGESCRPGLCGPGKCMNTADSYKC 406 NLCLN G C T Y C C G+ + C + E C C G C+N +Y C Sbjct: 417 NLCLN-GRCLP--TPSSYRCECNVGYTQDVRGECIDVDE-CTSSPCHHGDCVNIPGTYHC 472 Query: 407 AC 412 C Sbjct: 473 QC 474 Score = 33.5 bits (73), Expect = 0.48 Identities = 22/69 (31%), Positives = 29/69 (42%), Gaps = 5/69 (7%) Frame = +2 Query: 233 PNLCLNNGVCQEALTEHGYVCLCAPGFGGN----NCDRIGE-SCRPGLCGPGKCMNTADS 397 P +C + G C G+ CLC GF C + E P +C G C NT S Sbjct: 1204 PRVC-DQGHCTNM--PGGHRCLCYDGFMATPDMRTCVDVDECDLNPHICLHGDCENTKGS 1260 Query: 398 YKCACPVTY 424 + C C + Y Sbjct: 1261 FVCHCQLGY 1269 Score = 32.3 bits (70), Expect = 1.1 Identities = 12/23 (52%), Positives = 15/23 (65%) Frame = +2 Query: 359 LCGPGKCMNTADSYKCACPVTYT 427 LC G+C+ T SY+C C V YT Sbjct: 418 LCLNGRCLPTPSSYRCECNVGYT 440 Score = 31.5 bits (68), Expect = 1.9 Identities = 28/83 (33%), Positives = 34/83 (40%), Gaps = 12/83 (14%) Frame = +2 Query: 233 PNLCLNNGVCQEALTEHGYVCLCAPGF----GGNNC-DRIGESC----RPGLCGPGKCMN 385 PNLCL G C + + CLC PGF G+ C D C G C K N Sbjct: 1977 PNLCLF-GTCTNS--PGSFQCLCPPGFVLSDNGHRCFDTRQSFCFTRFEAGKCSVPKAFN 2033 Query: 386 TADSYKCAC---PVTYTGKNCEV 445 T + +C C P G CE+ Sbjct: 2034 TTKT-RCCCSKRPGEGWGDPCEL 2055 Score = 31.1 bits (67), Expect = 2.6 Identities = 12/32 (37%), Positives = 17/32 (53%) Frame = +2 Query: 329 DRIGESCRPGLCGPGKCMNTADSYKCACPVTY 424 D GE P +C G C+N S++C CP + Sbjct: 1723 DECGEI--PAICANGICINQIGSFRCECPAGF 1752 Score = 30.7 bits (66), Expect = 3.4 Identities = 21/70 (30%), Positives = 30/70 (42%), Gaps = 6/70 (8%) Frame = +2 Query: 233 PNLCLNNGVCQEALTEHGYVCLCAPGFGGNN----CDRIGE-SCRPGLCGPGK-CMNTAD 394 P +C N G+C + + C C GF N+ C+ + E R C C+N Sbjct: 1729 PAICAN-GICINQIGS--FRCECPAGFNYNSILLACEDVDECGSRESPCQQNADCINIPG 1785 Query: 395 SYKCACPVTY 424 SY+C C Y Sbjct: 1786 SYRCKCTRGY 1795 Score = 30.7 bits (66), Expect = 3.4 Identities = 22/76 (28%), Positives = 31/76 (40%), Gaps = 5/76 (6%) Frame = +2 Query: 212 QNCFTCAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNN----CDRIGESC-RPGLCGPGK 376 +N +P C + C+ L G+ C+C GF + C + E R G C Sbjct: 2569 ENECALSPPTC-GSASCRNTLG--GFRCVCPSGFDFDQALGGCQDVDECAGRRGPCSYS- 2624 Query: 377 CMNTADSYKCACPVTY 424 C NT + C CP Y Sbjct: 2625 CANTPGGFLCGCPQGY 2640 Score = 29.5 bits (63), Expect = 7.8 Identities = 25/81 (30%), Positives = 36/81 (44%), Gaps = 6/81 (7%) Frame = +2 Query: 203 ENVQNCFTCAPNLCLNNGVCQEALTEHGYVCLCAPGFGGN----NCDRIGESCRP--GLC 364 E++ C + + LC +G C + + C C GF C I E CR G C Sbjct: 1112 EDIDEC-SLSDGLC-PHGQCVNVIG--AFQCSCHAGFQSTPDRQGCVDINE-CRVQNGGC 1166 Query: 365 GPGKCMNTADSYKCACPVTYT 427 C+NT SY+C+C Y+ Sbjct: 1167 DV-HCINTEGSYRCSCGQGYS 1186 >AB053450-1|BAB47408.2| 2816|Homo sapiens fibrillin3 protein. Length = 2816 Score = 56.0 bits (129), Expect = 8e-08 Identities = 30/67 (44%), Positives = 36/67 (53%), Gaps = 5/67 (7%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHG-YVCLCAPGF----GGNNCDRIGESCRPGLCGPGKCMNTA 391 CA + NGVC L E G + CLC PGF GG+ C I E PG+C G C NT Sbjct: 542 CATSTMCVNGVC---LNEDGSFSCLCKPGFLLAPGGHYCMDIDECQTPGICVNGHCTNTE 598 Query: 392 DSYKCAC 412 S++C C Sbjct: 599 GSFRCQC 605 Score = 52.0 bits (119), Expect = 1e-06 Identities = 33/103 (32%), Positives = 49/103 (47%), Gaps = 10/103 (9%) Frame = +2 Query: 203 ENVQNCFTCAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNN----CDRIGE-SCRPGLCG 367 E++ C P LC G C T + C C PG+ + C+ I E S G+CG Sbjct: 1569 EDIDECQEL-PGLC-QGGDCVN--TFGSFQCECPPGYHLSEHTRICEDIDECSTHSGICG 1624 Query: 368 PGKCMNTADSYKCACPVTYT----GKNC-EVKQLIEYPAFTGS 481 PG C NT +Y C CP Y G NC ++++ + + + G+ Sbjct: 1625 PGTCYNTLGNYTCVCPAEYLQVNGGNNCMDMRKSVCFRHYNGT 1667 Score = 49.2 bits (112), Expect = 9e-06 Identities = 35/98 (35%), Positives = 44/98 (44%), Gaps = 12/98 (12%) Frame = +2 Query: 185 ALALEKENVQNCFTC--APNLCLNNGVCQEALTEHGYVCLCAPGFGGN-----NCDRIGE 343 AL ++ N + C +P+LC G C T + C C PG+ NC + E Sbjct: 1025 ALDAQERNCTDIDECRISPDLC-GQGTCVN--TPGSFECECFPGYESGFMLMKNCMDVDE 1081 Query: 344 SCR-PGLCGPGKCMNTADSYKCACP----VTYTGKNCE 442 R P LC G C NT SYKC CP +T G CE Sbjct: 1082 CARDPLLCRGGTCTNTDGSYKCQCPPGHELTAKGTACE 1119 Score = 48.0 bits (109), Expect = 2e-05 Identities = 28/66 (42%), Positives = 34/66 (51%), Gaps = 6/66 (9%) Frame = +2 Query: 233 PNLCLNNGVCQEALTEHGYVCLCAPGFG----GNNCDRIGESCR--PGLCGPGKCMNTAD 394 P LC +G C+ T + C CA GF NC I E CR P LCG G C+NT Sbjct: 1001 PGLC-THGTCRN--TVGSFHCACAGGFALDAQERNCTDIDE-CRISPDLCGQGTCVNTPG 1056 Query: 395 SYKCAC 412 S++C C Sbjct: 1057 SFECEC 1062 Score = 44.8 bits (101), Expect = 2e-04 Identities = 21/44 (47%), Positives = 27/44 (61%), Gaps = 5/44 (11%) Frame = +2 Query: 299 CAPGFG---GNNCDRIGESCR--PGLCGPGKCMNTADSYKCACP 415 CA GF G CD + E C PG+C G+C+NTA S++C CP Sbjct: 862 CARGFARMTGVTCDDVNE-CESFPGVCPNGRCVNTAGSFRCECP 904 Score = 44.8 bits (101), Expect = 2e-04 Identities = 28/73 (38%), Positives = 35/73 (47%), Gaps = 5/73 (6%) Frame = +2 Query: 212 QNCFTCAP-NLCLNNGVCQEALTEHGYVCLCAPGF----GGNNCDRIGESCRPGLCGPGK 376 Q+ CA NLC G C+ + C+C G+ GG NC I E P C G Sbjct: 1410 QDVDECAQGNLCAF-GSCENL--PGMFRCICNGGYELDRGGGNCTDINECADPVNCINGV 1466 Query: 377 CMNTADSYKCACP 415 C+NT SY C+CP Sbjct: 1467 CINTPGSYLCSCP 1479 Score = 44.0 bits (99), Expect = 3e-04 Identities = 26/64 (40%), Positives = 32/64 (50%), Gaps = 4/64 (6%) Frame = +2 Query: 233 PNLCLNNGVCQEALTEHGYVCLCAPGFGGNN----CDRIGESCRPGLCGPGKCMNTADSY 400 PN+C ++G C + TE Y+CLC GF + C I E C CG G C N SY Sbjct: 1820 PNVC-SHGDCMD--TEGSYMCLCHRGFQASADQTLCMDIDE-CDRQPCGNGTCKNIIGSY 1875 Query: 401 KCAC 412 C C Sbjct: 1876 NCLC 1879 Score = 44.0 bits (99), Expect = 3e-04 Identities = 27/73 (36%), Positives = 36/73 (49%), Gaps = 3/73 (4%) Frame = +2 Query: 206 NVQNCFTCAPNLCLNNGVCQEALTEHGYVCLCAPGFG--GNNCDRIGE-SCRPGLCGPGK 376 + C + A CL G CQ E + C+C PGF ++C I E S P LC G Sbjct: 1936 DTNECLSLA-GTCLP-GTCQNL--EGSFRCICPPGFQVQSDHCIDIDECSEEPNLCLFGT 1991 Query: 377 CMNTADSYKCACP 415 C N+ S++C CP Sbjct: 1992 CTNSPGSFQCLCP 2004 Score = 43.6 bits (98), Expect = 4e-04 Identities = 27/77 (35%), Positives = 37/77 (48%), Gaps = 7/77 (9%) Frame = +2 Query: 203 ENVQNCFTCA--PNLCLNNGVCQEALTEHGYVCLCAPGFG----GNNCDRIGE-SCRPGL 361 +N + CA P LC G C T+ Y C C PG G C+ I E S GL Sbjct: 1074 KNCMDVDECARDPLLC-RGGTCTN--TDGSYKCQCPPGHELTAKGTACEDIDECSLSDGL 1130 Query: 362 CGPGKCMNTADSYKCAC 412 C G+C+N +++C+C Sbjct: 1131 CPHGQCVNVIGAFQCSC 1147 Score = 42.7 bits (96), Expect = 8e-04 Identities = 24/83 (28%), Positives = 37/83 (44%), Gaps = 5/83 (6%) Frame = +2 Query: 182 MALALEKENVQNCFTCAPNLCLNNGVCQEALTEHGYVCLCAPGF----GGNNCDRIGESC 349 + + + ++ C P +C N GVC+ Y C+C G+ G +C + E Sbjct: 681 LGITTDGRDINEC-ALDPEVCAN-GVCENL--RGSYRCVCNLGYEAGASGKDCTDVDECA 736 Query: 350 RPGL-CGPGKCMNTADSYKCACP 415 L C G C N+ SY C+CP Sbjct: 737 LNSLLCDNGWCQNSPGSYSCSCP 759 Score = 42.3 bits (95), Expect = 0.001 Identities = 26/71 (36%), Positives = 31/71 (43%), Gaps = 4/71 (5%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGN---NCDRIGE-SCRPGLCGPGKCMNTAD 394 C+ G C + G+ C CA GF C+ I E S P LC +C NT Sbjct: 2137 CSVGHPCGQGTCTNVIG--GFECACADGFEPGLMMTCEDIDECSLNPLLCA-FRCHNTEG 2193 Query: 395 SYKCACPVTYT 427 SY C CP YT Sbjct: 2194 SYLCTCPAGYT 2204 Score = 41.5 bits (93), Expect = 0.002 Identities = 27/72 (37%), Positives = 36/72 (50%), Gaps = 9/72 (12%) Frame = +2 Query: 251 NGVCQEALTEHGYVCLCAPGF-GGNNCDRIG-ESCRP---GLCGPGKCMNTADSYKCAC- 412 NG C+ + Y CLC PGF +N D + + C +C G C+NTA S+ C C Sbjct: 1865 NGTCKNIIGS--YNCLCFPGFVVTHNGDCVDFDECTTLVGQVCRFGHCLNTAGSFHCLCQ 1922 Query: 413 ---PVTYTGKNC 439 +T GKNC Sbjct: 1923 DGFELTADGKNC 1934 Score = 40.3 bits (90), Expect = 0.004 Identities = 25/71 (35%), Positives = 29/71 (40%), Gaps = 5/71 (7%) Frame = +2 Query: 218 CFTCAPNLCLNNGVCQEALTEHGYVCLCAPGF----GGNNCDRIGESCR-PGLCGPGKCM 382 C T +C G C T + CLC GF G NC E G C PG C Sbjct: 1897 CTTLVGQVC-RFGHCLN--TAGSFHCLCQDGFELTADGKNCVDTNECLSLAGTCLPGTCQ 1953 Query: 383 NTADSYKCACP 415 N S++C CP Sbjct: 1954 NLEGSFRCICP 1964 Score = 40.3 bits (90), Expect = 0.004 Identities = 26/75 (34%), Positives = 33/75 (44%), Gaps = 4/75 (5%) Frame = +2 Query: 200 KENVQNCFTCAPNLCLNNGVCQEALTEHGYVCLCAPG----FGGNNCDRIGESCRPGLCG 367 +E+V C P +C NGVC T+ + C C G F G NC E CG Sbjct: 2089 REDVNECAE-NPGVC-TNGVCVN--TDGSFRCECPFGYSLDFTGINCVDTDECSVGHPCG 2144 Query: 368 PGKCMNTADSYKCAC 412 G C N ++CAC Sbjct: 2145 QGTCTNVIGGFECAC 2159 Score = 39.9 bits (89), Expect = 0.006 Identities = 26/67 (38%), Positives = 29/67 (43%), Gaps = 5/67 (7%) Frame = +2 Query: 227 CAPN-LCLNNGVCQEALTEHGYVCLCAPGF----GGNNCDRIGESCRPGLCGPGKCMNTA 391 CA N L +NG CQ + Y C C PGF C + E C C G C N A Sbjct: 735 CALNSLLCDNGWCQNS--PGSYSCSCPPGFHFWQDTEICKDVDE-CLSSPCVSGVCRNLA 791 Query: 392 DSYKCAC 412 SY C C Sbjct: 792 GSYTCKC 798 Score = 39.9 bits (89), Expect = 0.006 Identities = 18/48 (37%), Positives = 25/48 (52%), Gaps = 6/48 (12%) Frame = +2 Query: 287 YVCLCAPGF-----GGNNCDRIGES-CRPGLCGPGKCMNTADSYKCAC 412 + C+C PG G C E +P LC G+C+NTA S++C C Sbjct: 2239 FACVCPPGMRPLPGSGEGCTDDNECHAQPDLCVNGRCVNTAGSFRCDC 2286 Score = 39.5 bits (88), Expect = 0.007 Identities = 27/80 (33%), Positives = 33/80 (41%), Gaps = 9/80 (11%) Frame = +2 Query: 227 CAPNLCL-NNGVCQEALTEHGYVCLCAPGFGGNN----CDRIGESCRPGLCGPGKCMNTA 391 CA N+ L +NG C A GY C C GF C + E + LC G C N Sbjct: 1373 CAENVDLCDNGQCLNA--PGGYRCECEMGFDPTEDHRACQDVDECAQGNLCAFGSCENLP 1430 Query: 392 DSYKCACPVTYT----GKNC 439 ++C C Y G NC Sbjct: 1431 GMFRCICNGGYELDRGGGNC 1450 Score = 39.5 bits (88), Expect = 0.007 Identities = 22/69 (31%), Positives = 30/69 (43%), Gaps = 4/69 (5%) Frame = +2 Query: 233 PNLCLNNGVCQEALTEHGYVCLCAPGF----GGNNCDRIGESCRPGLCGPGKCMNTADSY 400 P C +G C T + C C GF G+ C+ + E P C G C N Y Sbjct: 2500 PGPCGAHGHCHN--TPGSFRCECHQGFTLVSSGHGCEDVNECDGPHRCQHG-CQNQLGGY 2556 Query: 401 KCACPVTYT 427 +C+CP +T Sbjct: 2557 RCSCPQGFT 2565 Score = 38.3 bits (85), Expect = 0.017 Identities = 22/60 (36%), Positives = 28/60 (46%), Gaps = 9/60 (15%) Frame = +2 Query: 287 YVCLCAPGFGGNN----CDRIGESC-RPGLCGPGKCMNTADSYKCACPVTY----TGKNC 439 Y C C PGF C + E GLC G+C+NT S++C C + GKNC Sbjct: 477 YHCRCYPGFQATPTRQACVDVDECIVSGGLCHLGRCVNTEGSFQCVCNAGFELSPDGKNC 536 Score = 38.3 bits (85), Expect = 0.017 Identities = 23/72 (31%), Positives = 33/72 (45%), Gaps = 5/72 (6%) Frame = +2 Query: 239 LCLNNGVCQ-EALTEHGYVCLCAPGFGGNNCDRIGESCRPGLCGPGKCMNTADSYKCACP 415 LC G + L G+ + P + + E+ PG+C G C+NT S++C CP Sbjct: 2062 LCPQEGSAAFQELCPFGHGAVPGPDDSREDVNECAEN--PGVCTNGVCVNTDGSFRCECP 2119 Query: 416 VTY----TGKNC 439 Y TG NC Sbjct: 2120 FGYSLDFTGINC 2131 Score = 37.5 bits (83), Expect = 0.029 Identities = 27/85 (31%), Positives = 38/85 (44%), Gaps = 6/85 (7%) Frame = +2 Query: 176 NIMALALEKENVQNCFTCAPNLCLNNGVCQEALTEHGYVCLCAPGFG---GNNCDRIGES 346 N ++ L E+V C + + C N C Y C C G+ G C +G++ Sbjct: 1760 NYNSILLACEDVDECGS-RESPCQQNADCINI--PGSYRCKCTRGYKLSPGGAC--VGQN 1814 Query: 347 -CR--PGLCGPGKCMNTADSYKCAC 412 CR P +C G CM+T SY C C Sbjct: 1815 ECREIPNVCSHGDCMDTEGSYMCLC 1839 Score = 37.1 bits (82), Expect = 0.039 Identities = 25/76 (32%), Positives = 33/76 (43%), Gaps = 5/76 (6%) Frame = +2 Query: 203 ENVQNCFTCAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNN----CDRIGE-SCRPGLCG 367 E+V C P+ C + CQ L GY C C GF ++ C E + P CG Sbjct: 2534 EDVNECD--GPHRCQHG--CQNQLG--GYRCSCPQGFTQHSQWAQCVDENECALSPPTCG 2587 Query: 368 PGKCMNTADSYKCACP 415 C NT ++C CP Sbjct: 2588 SASCRNTLGGFRCVCP 2603 Score = 35.9 bits (79), Expect = 0.090 Identities = 17/50 (34%), Positives = 22/50 (44%), Gaps = 4/50 (8%) Frame = +2 Query: 275 TEHGYVCLCAPGF----GGNNCDRIGESCRPGLCGPGKCMNTADSYKCAC 412 TE + C+C GF G NC E +C G C+N S+ C C Sbjct: 515 TEGSFQCVCNAGFELSPDGKNCVDHNECATSTMCVNGVCLNEDGSFSCLC 564 Score = 35.9 bits (79), Expect = 0.090 Identities = 16/49 (32%), Positives = 23/49 (46%), Gaps = 3/49 (6%) Frame = +2 Query: 287 YVCLCAPGFGGNN--CDRIGESCRP-GLCGPGKCMNTADSYKCACPVTY 424 Y C C GF G+ C+ E LC G+C+N Y+C C + + Sbjct: 1352 YRCTCRQGFAGDGFFCEDRDECAENVDLCDNGQCLNAPGGYRCECEMGF 1400 Score = 35.5 bits (78), Expect = 0.12 Identities = 19/57 (33%), Positives = 26/57 (45%), Gaps = 6/57 (10%) Frame = +2 Query: 287 YVCLCAPGFGGNNCDRIGESCR--PGLCGPGKCMNTADSYKCACPVTY----TGKNC 439 + LC+ G G R C P +C G C N SY+C C + Y +GK+C Sbjct: 673 FQALCSSGLGITTDGRDINECALDPEVCANGVCENLRGSYRCVCNLGYEAGASGKDC 729 Score = 35.1 bits (77), Expect = 0.16 Identities = 16/40 (40%), Positives = 20/40 (50%), Gaps = 2/40 (5%) Frame = +2 Query: 305 PGFGGNNCDRIGESCR--PGLCGPGKCMNTADSYKCACPV 418 P C + E C+ PGLC G C+N S+ C CPV Sbjct: 245 PNIHTGACQDVDE-CQAVPGLCQGGSCVNMVGSFHCRCPV 283 Score = 35.1 bits (77), Expect = 0.16 Identities = 18/49 (36%), Positives = 24/49 (48%), Gaps = 2/49 (4%) Frame = +2 Query: 287 YVCLCAPGFGGNNCDRIGESCR--PGLCGPGKCMNTADSYKCACPVTYT 427 Y LC G G R + CR LC G+C+N+ S++C C YT Sbjct: 2354 YRKLCPHGSGYTAEGRDVDECRMLAHLCAHGECINSLGSFRCHCQAGYT 2402 Score = 34.3 bits (75), Expect = 0.27 Identities = 25/83 (30%), Positives = 36/83 (43%), Gaps = 7/83 (8%) Frame = +2 Query: 233 PNLCLNNGVCQEALTEHGYVCLCAPGF----GGNNCDRIGESCRPG--LCGP-GKCMNTA 391 P++CL+ G C+ T+ +VC C G+ G C + E C G C C+N Sbjct: 1253 PHICLH-GDCEN--TKGSFVCHCQLGYMVRKGATGCSDVDE-CEVGGHNCDSHASCLNIP 1308 Query: 392 DSYKCACPVTYTGKNCEVKQLIE 460 S+ C C + G E L E Sbjct: 1309 GSFSCRCLPGWVGDGFECHDLDE 1331 Score = 34.3 bits (75), Expect = 0.27 Identities = 17/52 (32%), Positives = 25/52 (48%), Gaps = 4/52 (7%) Frame = +2 Query: 287 YVCLCAPGFGGNN--CDRIGESC-RPGLCGP-GKCMNTADSYKCACPVTYTG 430 + C C PG+ G+ C + E + C P G C+N SY+C C + G Sbjct: 1311 FSCRCLPGWVGDGFECHDLDECISQEHRCSPRGDCLNVPGSYRCTCRQGFAG 1362 Score = 33.9 bits (74), Expect = 0.36 Identities = 22/62 (35%), Positives = 27/62 (43%), Gaps = 3/62 (4%) Frame = +2 Query: 236 NLCLNNGVCQEALTEHGYVCLCAPGFGGN---NCDRIGESCRPGLCGPGKCMNTADSYKC 406 NLCLN G C T Y C C G+ + C + E C C G C+N +Y C Sbjct: 424 NLCLN-GRCLP--TPSSYRCECNVGYTQDVRGECIDVDE-CTSSPCHHGDCVNIPGTYHC 479 Query: 407 AC 412 C Sbjct: 480 RC 481 Score = 33.5 bits (73), Expect = 0.48 Identities = 22/69 (31%), Positives = 29/69 (42%), Gaps = 5/69 (7%) Frame = +2 Query: 233 PNLCLNNGVCQEALTEHGYVCLCAPGFGGN----NCDRIGE-SCRPGLCGPGKCMNTADS 397 P +C + G C G+ CLC GF C + E P +C G C NT S Sbjct: 1211 PRVC-DQGHCTNM--PGGHRCLCYDGFMATPDMRTCVDVDECDLNPHICLHGDCENTKGS 1267 Query: 398 YKCACPVTY 424 + C C + Y Sbjct: 1268 FVCHCQLGY 1276 Score = 32.3 bits (70), Expect = 1.1 Identities = 12/23 (52%), Positives = 15/23 (65%) Frame = +2 Query: 359 LCGPGKCMNTADSYKCACPVTYT 427 LC G+C+ T SY+C C V YT Sbjct: 425 LCLNGRCLPTPSSYRCECNVGYT 447 Score = 31.5 bits (68), Expect = 1.9 Identities = 28/83 (33%), Positives = 34/83 (40%), Gaps = 12/83 (14%) Frame = +2 Query: 233 PNLCLNNGVCQEALTEHGYVCLCAPGF----GGNNC-DRIGESC----RPGLCGPGKCMN 385 PNLCL G C + + CLC PGF G+ C D C G C K N Sbjct: 1984 PNLCLF-GTCTNS--PGSFQCLCPPGFVLSDNGHRCFDTRQSFCFTRFEAGKCSVPKAFN 2040 Query: 386 TADSYKCAC---PVTYTGKNCEV 445 T + +C C P G CE+ Sbjct: 2041 TTKT-RCCCSKRPGEGWGDPCEL 2062 Score = 31.1 bits (67), Expect = 2.6 Identities = 12/32 (37%), Positives = 17/32 (53%) Frame = +2 Query: 329 DRIGESCRPGLCGPGKCMNTADSYKCACPVTY 424 D GE P +C G C+N S++C CP + Sbjct: 1730 DECGEI--PAICANGICINQIGSFRCECPAGF 1759 Score = 30.7 bits (66), Expect = 3.4 Identities = 21/70 (30%), Positives = 30/70 (42%), Gaps = 6/70 (8%) Frame = +2 Query: 233 PNLCLNNGVCQEALTEHGYVCLCAPGFGGNN----CDRIGE-SCRPGLCGPGK-CMNTAD 394 P +C N G+C + + C C GF N+ C+ + E R C C+N Sbjct: 1736 PAICAN-GICINQIGS--FRCECPAGFNYNSILLACEDVDECGSRESPCQQNADCINIPG 1792 Query: 395 SYKCACPVTY 424 SY+C C Y Sbjct: 1793 SYRCKCTRGY 1802 Score = 30.7 bits (66), Expect = 3.4 Identities = 22/76 (28%), Positives = 31/76 (40%), Gaps = 5/76 (6%) Frame = +2 Query: 212 QNCFTCAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNN----CDRIGESC-RPGLCGPGK 376 +N +P C + C+ L G+ C+C GF + C + E R G C Sbjct: 2576 ENECALSPPTC-GSASCRNTLG--GFRCVCPSGFDFDQALGGCQDVDECAGRRGPCSYS- 2631 Query: 377 CMNTADSYKCACPVTY 424 C NT + C CP Y Sbjct: 2632 CANTPGGFLCGCPQGY 2647 Score = 29.5 bits (63), Expect = 7.8 Identities = 25/81 (30%), Positives = 36/81 (44%), Gaps = 6/81 (7%) Frame = +2 Query: 203 ENVQNCFTCAPNLCLNNGVCQEALTEHGYVCLCAPGFGGN----NCDRIGESCRP--GLC 364 E++ C + + LC +G C + + C C GF C I E CR G C Sbjct: 1119 EDIDEC-SLSDGLC-PHGQCVNVIG--AFQCSCHAGFQSTPDRQGCVDINE-CRVQNGGC 1173 Query: 365 GPGKCMNTADSYKCACPVTYT 427 C+NT SY+C+C Y+ Sbjct: 1174 DV-HCINTEGSYRCSCGQGYS 1193 >X63556-1|CAA45118.1| 3002|Homo sapiens fibrillin protein. Length = 3002 Score = 55.6 bits (128), Expect = 1e-07 Identities = 30/76 (39%), Positives = 43/76 (56%), Gaps = 6/76 (7%) Frame = +2 Query: 203 ENVQNCFTCA-PNLCLNNGVCQEALTEHG-YVCLCAPGF----GGNNCDRIGESCRPGLC 364 +N ++ C+ N+CLN G+C + E G + C+C PGF G C I E PG+C Sbjct: 699 KNCEDMDECSIRNMCLN-GMC---INEDGSFKCICKPGFQLASDGRYCKDINECETPGIC 754 Query: 365 GPGKCMNTADSYKCAC 412 G+C+NT SY+C C Sbjct: 755 MNGRCVNTDGSYRCEC 770 Score = 55.2 bits (127), Expect = 1e-07 Identities = 32/87 (36%), Positives = 39/87 (44%), Gaps = 8/87 (9%) Frame = +2 Query: 203 ENVQNCFTCAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNN----CDRIGESCRPGLCGP 370 E++ C P LC G C T + C C G+ N CD + E PG+CGP Sbjct: 1736 EDIDECQEL-PGLC-QGGKCIN--TFGSFQCRCPTGYYLNEDTRVCDDVNECETPGICGP 1791 Query: 371 GKCMNTADSYKCACPVTYT----GKNC 439 G C NT +Y C CP Y G NC Sbjct: 1792 GTCYNTVGNYTCICPPDYMQVNGGNNC 1818 Score = 50.0 bits (114), Expect = 5e-06 Identities = 33/95 (34%), Positives = 43/95 (45%), Gaps = 8/95 (8%) Frame = +2 Query: 206 NVQNCFTCAPNLCLNNGVCQEALTEHGYVCLCAPGF----GGNNCDRIGESC-RPGLCGP 370 +V C + NLC NG C T + C C G+ G C I E P C P Sbjct: 2061 DVDECASGNGNLC-RNGQCIN--TVGSFQCQCNEGYEVAPDGRTCVDINECLLEPRKCAP 2117 Query: 371 GKCMNTADSYKCACPVTYTGKN--CE-VKQLIEYP 466 G C N SY+C CP Y+ +N CE + + +E P Sbjct: 2118 GTCQNLDGSYRCICPPGYSLQNEKCEDIDECVEEP 2152 Score = 49.6 bits (113), Expect = 7e-06 Identities = 28/83 (33%), Positives = 41/83 (49%), Gaps = 8/83 (9%) Frame = +2 Query: 254 GVCQEALTEHGYVCLCAPGFGGNN--CDRIGESCR-PGLCGPGKCMNTADSYKCACP--- 415 G CQ + Y C+C PG+ N C+ I E P +C G C NT S+KC CP Sbjct: 2118 GTCQNL--DGSYRCICPPGYSLQNEKCEDIDECVEEPEICALGTCSNTEGSFKCLCPEGF 2175 Query: 416 -VTYTGKNC-EVKQLIEYPAFTG 478 ++ +G+ C +++ Y F G Sbjct: 2176 SLSSSGRRCQDLRMSYCYAKFEG 2198 Score = 46.0 bits (104), Expect = 8e-05 Identities = 29/83 (34%), Positives = 40/83 (48%), Gaps = 7/83 (8%) Frame = +2 Query: 233 PNLCLNNGVCQEALTEHGYVCLCAPGFGGNN----CDRIGESCRPGLCGPGK---CMNTA 391 PN+CL+ G C+ T+ ++C C G+ G C I E C G GK C NTA Sbjct: 1419 PNICLS-GTCEN--TKGSFICHCDMGYSGKKGKTGCTDINE-CEIGAHNCGKHAVCTNTA 1474 Query: 392 DSYKCACPVTYTGKNCEVKQLIE 460 S+KC+C + G + L E Sbjct: 1475 GSFKCSCSPGWIGDGIKCTDLDE 1497 Score = 46.0 bits (104), Expect = 8e-05 Identities = 20/52 (38%), Positives = 28/52 (53%), Gaps = 5/52 (9%) Frame = +2 Query: 287 YVCLCAPGF----GGNNCDRIGE-SCRPGLCGPGKCMNTADSYKCACPVTYT 427 Y+C+C PG+ G C E +PG+C G+C+NT SY C C +T Sbjct: 2403 YMCICGPGYQRRPDGEGCVDENECQTKPGICENGRCLNTRGSYTCECNDGFT 2454 Score = 45.2 bits (102), Expect = 1e-04 Identities = 29/80 (36%), Positives = 36/80 (45%), Gaps = 9/80 (11%) Frame = +2 Query: 227 CAPNLCL-NNGVCQEALTEHGYVCLCAPGF----GGNNCDRIGESCRPGLCGPGKCMNTA 391 C+ NL L NG C A GY C C GF G C+ I E P +C G C N Sbjct: 1539 CSENLNLCGNGQCLNA--PGGYRCECDMGFVPSADGKACEDIDECSLPNICVFGTCHNLP 1596 Query: 392 DSYKCACPVTY----TGKNC 439 ++C C + Y +G NC Sbjct: 1597 GLFRCECEIGYELDRSGGNC 1616 Score = 44.8 bits (101), Expect = 2e-04 Identities = 26/70 (37%), Positives = 35/70 (50%), Gaps = 6/70 (8%) Frame = +2 Query: 233 PNLCLNNGVCQEALTEHGYVCLCAPGFG----GNNCDRIGESCR--PGLCGPGKCMNTAD 394 P+LC +G C+ + + C C GF NC I E CR P LCG G+C+NT Sbjct: 1167 PSLC-THGKCRNTIGS--FKCRCDSGFALDSEERNCTDIDE-CRISPDLCGRGQCVNTPG 1222 Query: 395 SYKCACPVTY 424 ++C C Y Sbjct: 1223 DFECKCDEGY 1232 Score = 44.4 bits (100), Expect = 3e-04 Identities = 24/66 (36%), Positives = 32/66 (48%), Gaps = 3/66 (4%) Frame = +2 Query: 236 NLCLNNGVCQEALTEHGYVCLCAPGFGGN---NCDRIGESCRPGLCGPGKCMNTADSYKC 406 N C NG C+ + G+ C C GF C+ I E + L +C+NT SY+C Sbjct: 2305 NPC-GNGTCKNVIG--GFECTCEEGFEPGPMMTCEDINECAQNPLLCAFRCVNTYGSYEC 2361 Query: 407 ACPVTY 424 CPV Y Sbjct: 2362 KCPVGY 2367 Score = 44.0 bits (99), Expect = 3e-04 Identities = 26/72 (36%), Positives = 34/72 (47%), Gaps = 5/72 (6%) Frame = +2 Query: 233 PNLCLNNGVCQEALTEHGYVCLCAPGFGGNN----CDRIGE-SCRPGLCGPGKCMNTADS 397 PN+C + G C E Y CLC GF + C + E P +C G C NT S Sbjct: 1377 PNIC-DGGQCTNIPGE--YRCLCYDGFMASEDMKTCVDVNECDLNPNICLSGTCENTKGS 1433 Query: 398 YKCACPVTYTGK 433 + C C + Y+GK Sbjct: 1434 FICHCDMGYSGK 1445 Score = 44.0 bits (99), Expect = 3e-04 Identities = 25/64 (39%), Positives = 32/64 (50%), Gaps = 4/64 (6%) Frame = +2 Query: 233 PNLCLNNGVCQEALTEHGYVCLCAPGFGGNN----CDRIGESCRPGLCGPGKCMNTADSY 400 PN+C ++G C + T + CLC GF N+ C I E C CG G C NT S+ Sbjct: 1988 PNIC-SHGQCID--TVGSFYCLCHTGFKTNDDQTMCLDINE-CERDACGNGTCRNTIGSF 2043 Query: 401 KCAC 412 C C Sbjct: 2044 NCRC 2047 Score = 43.6 bits (98), Expect = 4e-04 Identities = 24/66 (36%), Positives = 32/66 (48%), Gaps = 5/66 (7%) Frame = +2 Query: 233 PNLCLNNGVCQEALTEHGYVCLCAPGFG----GNNCDRIGESCRPGL-CGPGKCMNTADS 397 P++C NG+C+ Y C+C G+ G NC I E L C G+C NT S Sbjct: 862 PDIC-PNGICENL--RGTYKCICNSGYEVDSTGKNCVDINECVLNSLLCDNGQCRNTPGS 918 Query: 398 YKCACP 415 + C CP Sbjct: 919 FVCTCP 924 Score = 43.2 bits (97), Expect = 6e-04 Identities = 25/75 (33%), Positives = 33/75 (44%), Gaps = 4/75 (5%) Frame = +2 Query: 203 ENVQNCFTCAPNLCLNNGVCQEALTEHGYVCLCAPGF----GGNNCDRIGESCRPGLCGP 370 E++ C PN+C+ G C + C C G+ G NC + E P C Sbjct: 1576 EDIDEC--SLPNICVF-GTCHNL--PGLFRCECEIGYELDRSGGNCTDVNECLDPTTCIS 1630 Query: 371 GKCMNTADSYKCACP 415 G C+NT SY C CP Sbjct: 1631 GNCVNTPGSYICDCP 1645 Score = 42.7 bits (96), Expect = 8e-04 Identities = 28/76 (36%), Positives = 34/76 (44%), Gaps = 5/76 (6%) Frame = +2 Query: 203 ENVQNCFTCAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNN----CDRIGE-SCRPGLCG 367 ++V C P LC G C T + C C G N C+ I E S PG+C Sbjct: 376 QDVDEC-QAIPGLC-QGGNCIN--TVGSFECKCPAGHKLNEVSQKCEDIDECSTIPGICE 431 Query: 368 PGKCMNTADSYKCACP 415 G+C NT SY C CP Sbjct: 432 GGECTNTVSSYFCKCP 447 Score = 42.3 bits (95), Expect = 0.001 Identities = 31/85 (36%), Positives = 38/85 (44%), Gaps = 8/85 (9%) Frame = +2 Query: 185 ALALEKENVQNCFTC--APNLCLNNGVCQEALTEHGYVCLCAPGFGGN-----NCDRIGE 343 AL E+ N + C +P+LC G C T + C C G+ NC I E Sbjct: 1191 ALDSEERNCTDIDECRISPDLC-GRGQCVN--TPGDFECKCDEGYESGFMMMKNCMDIDE 1247 Query: 344 SCR-PGLCGPGKCMNTADSYKCACP 415 R P LC G C NT SY+C CP Sbjct: 1248 CQRDPLLCRGGVCHNTEGSYRCECP 1272 Score = 41.9 bits (94), Expect = 0.001 Identities = 22/65 (33%), Positives = 31/65 (47%), Gaps = 8/65 (12%) Frame = +2 Query: 242 CLNNG-VCQEAL---TEHGYVCLCAPGF----GGNNCDRIGESCRPGLCGPGKCMNTADS 397 CL NG +C T+ + C+C GF G NC+ + E +C G C+N S Sbjct: 665 CLQNGRICNNGRCINTDGSFHCVCNAGFHVTRDGKNCEDMDECSIRNMCLNGMCINEDGS 724 Query: 398 YKCAC 412 +KC C Sbjct: 725 FKCIC 729 Score = 41.9 bits (94), Expect = 0.001 Identities = 23/67 (34%), Positives = 26/67 (38%), Gaps = 6/67 (8%) Frame = +2 Query: 242 CLNNGVCQEALTE--HGYVCLCAPGF----GGNNCDRIGESCRPGLCGPGKCMNTADSYK 403 C N CQ GY C C G+ N C E +CG C NT SYK Sbjct: 2702 CEGNHRCQHGCQNIIGGYRCSCPQGYLQHYQWNQCVDENECLSAHICGGASCHNTLGSYK 2761 Query: 404 CACPVTY 424 C CP + Sbjct: 2762 CMCPAGF 2768 Score = 41.5 bits (93), Expect = 0.002 Identities = 25/78 (32%), Positives = 36/78 (46%) Frame = +2 Query: 242 CLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLCGPGKCMNTADSYKCACPVT 421 C+N G C + +H CLC G+ G +C + C G G+C+ +CAC Sbjct: 254 CMNGGSCSD---DH---CLCQKGYIGTHCGQ--PVCESGCLNGGRCVAPN---RCACTYG 302 Query: 422 YTGKNCEVKQLIEYPAFT 475 +TG CE + P FT Sbjct: 303 FTGPQCE-RDYRTGPCFT 319 Score = 40.7 bits (91), Expect = 0.003 Identities = 22/61 (36%), Positives = 27/61 (44%), Gaps = 7/61 (11%) Frame = +2 Query: 251 NGVCQEALT--EHGYVCLCAPGFG----GNNCDRIGE-SCRPGLCGPGKCMNTADSYKCA 409 NG C+ T E Y C C PGF +C I E P +C G+C N Y+C Sbjct: 1336 NGGCETFCTNSEGSYECSCQPGFALMPDQRSCTDIDECEDNPNICDGGQCTNIPGEYRCL 1395 Query: 410 C 412 C Sbjct: 1396 C 1396 Score = 40.3 bits (90), Expect = 0.004 Identities = 19/45 (42%), Positives = 25/45 (55%), Gaps = 5/45 (11%) Frame = +2 Query: 296 LCAPGFG---GNNCDRIGESCR--PGLCGPGKCMNTADSYKCACP 415 +C G+ G C+ I E C PG+C G C+NT S+KC CP Sbjct: 1026 ICGKGYSRIKGTQCEDIDE-CEVFPGVCKNGLCVNTRGSFKCQCP 1069 Score = 40.3 bits (90), Expect = 0.004 Identities = 27/80 (33%), Positives = 37/80 (46%), Gaps = 5/80 (6%) Frame = +2 Query: 206 NVQNCFTCAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNN--CDRIGESCRPG--LCGP- 370 ++ C A N C + VC T + C C+PG+ G+ C + E C G +C Sbjct: 1453 DINECEIGAHN-CGKHAVCTN--TAGSFKCSCSPGWIGDGIKCTDLDE-CSNGTHMCSQH 1508 Query: 371 GKCMNTADSYKCACPVTYTG 430 C NT SY+C C YTG Sbjct: 1509 ADCKNTMGSYRCLCKEGYTG 1528 Score = 39.1 bits (87), Expect = 0.010 Identities = 16/36 (44%), Positives = 22/36 (61%), Gaps = 3/36 (8%) Frame = +2 Query: 341 ESCR-PGLCGPGKCMNTADSYKCACPVTYT--GKNC 439 + C+ P +C G+C+NT SY+C CP YT G C Sbjct: 2260 DECKEPDVCKHGQCINTDGSYRCECPFGYTLAGNEC 2295 Score = 38.7 bits (86), Expect = 0.013 Identities = 26/69 (37%), Positives = 30/69 (43%), Gaps = 5/69 (7%) Frame = +2 Query: 233 PNLCLNNGVCQEALTEHGYVCLCAPGF----GGNNCDRIGE-SCRPGLCGPGKCMNTADS 397 P LC GVC TE Y C C PG + C I E LC G+C+N Sbjct: 1252 PLLC-RGGVCHN--TEGSYRCECPPGHQLSPNISACIDINECELSAHLCPNGRCVNLIGK 1308 Query: 398 YKCACPVTY 424 Y+CAC Y Sbjct: 1309 YQCACNPGY 1317 Score = 37.5 bits (83), Expect = 0.029 Identities = 21/54 (38%), Positives = 27/54 (50%), Gaps = 2/54 (3%) Frame = +2 Query: 305 PGFGGNNCDRIGESCR--PGLCGPGKCMNTADSYKCACPVTYTGKNCEVKQLIE 460 P C + E C+ PGLC G C+NT S++C CP + K EV Q E Sbjct: 368 PNIRTGACQDVDE-CQAIPGLCQGGNCINTVGSFECKCPAGH--KLNEVSQKCE 418 Score = 37.1 bits (82), Expect = 0.039 Identities = 22/61 (36%), Positives = 29/61 (47%), Gaps = 8/61 (13%) Frame = +2 Query: 284 GYVCLCAPGFGGNNCDRIGES-CRP--GLCGP-GKCMNTADSYKCAC----PVTYTGKNC 439 G+ C C PGF ++ I + C LCG G C NT S+ C C + TG +C Sbjct: 2637 GFTCKCPPGFTQHHTSCIDNNECTSDINLCGSKGICQNTPGSFTCECQRGFSLDQTGSSC 2696 Query: 440 E 442 E Sbjct: 2697 E 2697 Score = 36.7 bits (81), Expect = 0.052 Identities = 21/57 (36%), Positives = 25/57 (43%), Gaps = 6/57 (10%) Frame = +2 Query: 287 YVCLCAPGFGGNNCDRIGESCR--PGLCGPGKCMNTADSYKCACPVTY----TGKNC 439 Y LC+ G G + C P +C G C N +YKC C Y TGKNC Sbjct: 838 YQALCSSGPGMTSAGSDINECALDPDICPNGICENLRGTYKCICNSGYEVDSTGKNC 894 Score = 36.7 bits (81), Expect = 0.052 Identities = 24/69 (34%), Positives = 33/69 (47%), Gaps = 5/69 (7%) Frame = +2 Query: 233 PNLCLNNGVCQEALTEHGYVCLCAPGFGGNN----CDRIGESCRPGLCGPG-KCMNTADS 397 P +C NGVC + + C C GF N+ C+ I E +C +C+NTA S Sbjct: 1905 PGVC-ENGVCINMVGS--FRCECPVGFFYNDKLLVCEDIDECQNGPVCQRNAECINTAGS 1961 Query: 398 YKCACPVTY 424 Y+C C Y Sbjct: 1962 YRCDCKPGY 1970 Score = 36.7 bits (81), Expect = 0.052 Identities = 20/62 (32%), Positives = 27/62 (43%), Gaps = 2/62 (3%) Frame = +2 Query: 233 PNLCLNNGVCQEALTEHGYVCLCAPGF--GGNNCDRIGESCRPGLCGPGKCMNTADSYKC 406 P++C +G C T+ Y C C G+ GN C E CG G C N ++C Sbjct: 2265 PDVC-KHGQCIN--TDGSYRCECPFGYTLAGNECVDTDECSVGNPCGNGTCKNVIGGFEC 2321 Query: 407 AC 412 C Sbjct: 2322 TC 2323 Score = 35.5 bits (78), Expect = 0.12 Identities = 13/30 (43%), Positives = 19/30 (63%), Gaps = 2/30 (6%) Frame = +2 Query: 341 ESCR--PGLCGPGKCMNTADSYKCACPVTY 424 + CR PG+C G C+N S++C CPV + Sbjct: 1899 DECREIPGVCENGVCINMVGSFRCECPVGF 1928 Score = 35.1 bits (77), Expect = 0.16 Identities = 23/65 (35%), Positives = 26/65 (40%), Gaps = 3/65 (4%) Frame = +2 Query: 239 LCLNNGVCQEALTEHGYVCLCAPGFG---GNNCDRIGESCRPGLCGPGKCMNTADSYKCA 409 LC NG C T Y C C GF C + E C C G+C+N SY C Sbjct: 590 LC-QNGRCIP--TPGSYRCECNKGFQLDLRGECIDVDE-CEKNPCAGGECINNQGSYTCQ 645 Query: 410 CPVTY 424 C Y Sbjct: 646 CRAGY 650 Score = 35.1 bits (77), Expect = 0.16 Identities = 21/63 (33%), Positives = 28/63 (44%), Gaps = 4/63 (6%) Frame = +2 Query: 236 NLCLNNGVCQEALTEHGYVCLCAPGF----GGNNCDRIGESCRPGLCGPGKCMNTADSYK 403 +L +NG C+ T +VC C GF C+ I E C C G C N+ S+ Sbjct: 904 SLLCDNGQCRN--TPGSFVCTCPKGFIYKPDLKTCEDIDE-CESSPCINGVCKNSPGSFI 960 Query: 404 CAC 412 C C Sbjct: 961 CEC 963 Score = 33.9 bits (74), Expect = 0.36 Identities = 23/71 (32%), Positives = 27/71 (38%), Gaps = 8/71 (11%) Frame = +2 Query: 236 NLCLNNGVCQEALTEH---GYVCLCAPGFG----GNNCDRIGE-SCRPGLCGPGKCMNTA 391 N CL+ +C A + Y C+C GF C I E C G C NT Sbjct: 2740 NECLSAHICGGASCHNTLGSYKCMCPAGFQYEQFSGGCQDINECGSAQAPCSYG-CSNTE 2798 Query: 392 DSYKCACPVTY 424 Y C CP Y Sbjct: 2799 GGYLCGCPPGY 2809 Score = 33.5 bits (73), Expect = 0.48 Identities = 24/74 (32%), Positives = 37/74 (50%), Gaps = 12/74 (16%) Frame = +2 Query: 257 VCQ--EALTEHG-YVCLCAPGFG----GNNCDRIGESCR-PGLCGPGKCMNTADSYKCAC 412 VC+ E + + G Y C+C G+ G +C + E + P C C NT SY+C+C Sbjct: 2543 VCRNGECVNDRGSYHCICKTGYTPDITGTSCVDLNECNQAPKPCN-FICKNTEGSYQCSC 2601 Query: 413 PVTY----TGKNCE 442 P Y G++C+ Sbjct: 2602 PKGYILQEDGRSCK 2615 Score = 33.5 bits (73), Expect = 0.48 Identities = 21/70 (30%), Positives = 29/70 (41%), Gaps = 4/70 (5%) Frame = +2 Query: 230 APNLCLNNGVCQEALTEHGYVCLCAPGF----GGNNCDRIGESCRPGLCGPGKCMNTADS 397 AP C N +C+ TE Y C C G+ G +C + E C+NT Sbjct: 2582 APKPC--NFICKN--TEGSYQCSCPKGYILQEDGRSCKDLDECATKQHNCQFLCVNTIGG 2637 Query: 398 YKCACPVTYT 427 + C CP +T Sbjct: 2638 FTCKCPPGFT 2647 Score = 29.9 bits (64), Expect = 5.9 Identities = 15/46 (32%), Positives = 19/46 (41%) Frame = +2 Query: 290 VCLCAPGFGGNNCDRIGESCRPGLCGPGKCMNTADSYKCACPVTYT 427 +C GF N D +C G+C+N SY C C YT Sbjct: 2520 LCPHGRGFMTNGADIDECKVIHDVCRNGECVNDRGSYHCICKTGYT 2565 Score = 29.5 bits (63), Expect = 7.8 Identities = 20/65 (30%), Positives = 27/65 (41%), Gaps = 4/65 (6%) Frame = +2 Query: 203 ENVQNCFTCAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLC----GP 370 E++ C T P +C G C ++ Y C C PGF + RPG C Sbjct: 418 EDIDECSTI-PGIC-EGGECTNTVSS--YFCKCPPGFYTSPDGTRCIDVRPGYCYTALTN 473 Query: 371 GKCMN 385 G+C N Sbjct: 474 GRCSN 478 >M59303-1|AAA36499.1| 320|Homo sapiens protein Z protein. Length = 320 Score = 55.6 bits (128), Expect = 1e-07 Identities = 24/68 (35%), Positives = 36/68 (52%), Gaps = 2/68 (2%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLCGPGK--CMNTADSY 400 C CL+NG CQ+++ GY C C+PG+ G+NC+ C P + C+ +SY Sbjct: 11 CISQPCLHNGSCQDSIW--GYTCTCSPGYEGSNCELAKNECHPERTDGCQHFCLPGQESY 68 Query: 401 KCACPVTY 424 C+C Y Sbjct: 69 TCSCAQGY 76 Score = 29.9 bits (64), Expect = 5.9 Identities = 10/25 (40%), Positives = 13/25 (52%) Frame = +2 Query: 371 GKCMNTADSYKCACPVTYTGKNCEV 445 G C ++ Y C C Y G NCE+ Sbjct: 20 GSCQDSIWGYTCTCSPGYEGSNCEL 44 >M55671-1|AAA36501.1| 422|Homo sapiens protein Z protein. Length = 422 Score = 55.6 bits (128), Expect = 1e-07 Identities = 24/68 (35%), Positives = 36/68 (52%), Gaps = 2/68 (2%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLCGPGK--CMNTADSY 400 C CL+NG CQ+++ GY C C+PG+ G+NC+ C P + C+ +SY Sbjct: 113 CISQPCLHNGSCQDSIW--GYTCTCSPGYEGSNCELAKNECHPERTDGCQHFCLPGQESY 170 Query: 401 KCACPVTY 424 C+C Y Sbjct: 171 TCSCAQGY 178 Score = 29.9 bits (64), Expect = 5.9 Identities = 10/25 (40%), Positives = 13/25 (52%) Frame = +2 Query: 371 GKCMNTADSYKCACPVTYTGKNCEV 445 G C ++ Y C C Y G NCE+ Sbjct: 122 GSCQDSIWGYTCTCSPGYEGSNCEL 146 >M55670-1|AAA36500.1| 400|Homo sapiens protein Z protein. Length = 400 Score = 55.6 bits (128), Expect = 1e-07 Identities = 24/68 (35%), Positives = 36/68 (52%), Gaps = 2/68 (2%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLCGPGK--CMNTADSY 400 C CL+NG CQ+++ GY C C+PG+ G+NC+ C P + C+ +SY Sbjct: 91 CISQPCLHNGSCQDSIW--GYTCTCSPGYEGSNCELAKNECHPERTDGCQHFCLPGQESY 148 Query: 401 KCACPVTY 424 C+C Y Sbjct: 149 TCSCAQGY 156 Score = 29.9 bits (64), Expect = 5.9 Identities = 10/25 (40%), Positives = 13/25 (52%) Frame = +2 Query: 371 GKCMNTADSYKCACPVTYTGKNCEV 445 G C ++ Y C C Y G NCE+ Sbjct: 100 GSCQDSIWGYTCTCSPGYEGSNCEL 124 >L13923-1|AAB02036.1| 2871|Homo sapiens fibrillin protein. Length = 2871 Score = 55.6 bits (128), Expect = 1e-07 Identities = 30/76 (39%), Positives = 43/76 (56%), Gaps = 6/76 (7%) Frame = +2 Query: 203 ENVQNCFTCA-PNLCLNNGVCQEALTEHG-YVCLCAPGF----GGNNCDRIGESCRPGLC 364 +N ++ C+ N+CLN G+C + E G + C+C PGF G C I E PG+C Sbjct: 568 KNCEDMDECSIRNMCLN-GMC---INEDGSFKCICKPGFQLASDGRYCKDINECETPGIC 623 Query: 365 GPGKCMNTADSYKCAC 412 G+C+NT SY+C C Sbjct: 624 MNGRCVNTDGSYRCEC 639 Score = 55.2 bits (127), Expect = 1e-07 Identities = 32/87 (36%), Positives = 39/87 (44%), Gaps = 8/87 (9%) Frame = +2 Query: 203 ENVQNCFTCAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNN----CDRIGESCRPGLCGP 370 E++ C P LC G C T + C C G+ N CD + E PG+CGP Sbjct: 1605 EDIDECQEL-PGLC-QGGKCIN--TFGSFQCRCPTGYYLNEDTRVCDDVNECETPGICGP 1660 Query: 371 GKCMNTADSYKCACPVTYT----GKNC 439 G C NT +Y C CP Y G NC Sbjct: 1661 GTCYNTVGNYTCICPPDYMQVNGGNNC 1687 Score = 50.0 bits (114), Expect = 5e-06 Identities = 33/95 (34%), Positives = 43/95 (45%), Gaps = 8/95 (8%) Frame = +2 Query: 206 NVQNCFTCAPNLCLNNGVCQEALTEHGYVCLCAPGF----GGNNCDRIGESC-RPGLCGP 370 +V C + NLC NG C T + C C G+ G C I E P C P Sbjct: 1930 DVDECASGNGNLC-RNGQCIN--TVGSFQCQCNEGYEVAPDGRTCVDINECLLEPRKCAP 1986 Query: 371 GKCMNTADSYKCACPVTYTGKN--CE-VKQLIEYP 466 G C N SY+C CP Y+ +N CE + + +E P Sbjct: 1987 GTCQNLDGSYRCICPPGYSLQNEKCEDIDECVEEP 2021 Score = 49.6 bits (113), Expect = 7e-06 Identities = 28/83 (33%), Positives = 41/83 (49%), Gaps = 8/83 (9%) Frame = +2 Query: 254 GVCQEALTEHGYVCLCAPGFGGNN--CDRIGESCR-PGLCGPGKCMNTADSYKCACP--- 415 G CQ + Y C+C PG+ N C+ I E P +C G C NT S+KC CP Sbjct: 1987 GTCQNL--DGSYRCICPPGYSLQNEKCEDIDECVEEPEICALGTCSNTEGSFKCLCPEGF 2044 Query: 416 -VTYTGKNC-EVKQLIEYPAFTG 478 ++ +G+ C +++ Y F G Sbjct: 2045 SLSSSGRRCQDLRMSYCYAKFEG 2067 Score = 46.0 bits (104), Expect = 8e-05 Identities = 29/83 (34%), Positives = 40/83 (48%), Gaps = 7/83 (8%) Frame = +2 Query: 233 PNLCLNNGVCQEALTEHGYVCLCAPGFGGNN----CDRIGESCRPGLCGPGK---CMNTA 391 PN+CL+ G C+ T+ ++C C G+ G C I E C G GK C NTA Sbjct: 1288 PNICLS-GTCEN--TKGSFICHCDMGYSGKKGKTGCTDINE-CEIGAHNCGKHAVCTNTA 1343 Query: 392 DSYKCACPVTYTGKNCEVKQLIE 460 S+KC+C + G + L E Sbjct: 1344 GSFKCSCSPGWIGDGIKCTDLDE 1366 Score = 46.0 bits (104), Expect = 8e-05 Identities = 20/52 (38%), Positives = 28/52 (53%), Gaps = 5/52 (9%) Frame = +2 Query: 287 YVCLCAPGF----GGNNCDRIGE-SCRPGLCGPGKCMNTADSYKCACPVTYT 427 Y+C+C PG+ G C E +PG+C G+C+NT SY C C +T Sbjct: 2272 YMCICGPGYQRRPDGEGCVDENECQTKPGICENGRCLNTRGSYTCECNDGFT 2323 Score = 45.2 bits (102), Expect = 1e-04 Identities = 29/80 (36%), Positives = 36/80 (45%), Gaps = 9/80 (11%) Frame = +2 Query: 227 CAPNLCL-NNGVCQEALTEHGYVCLCAPGF----GGNNCDRIGESCRPGLCGPGKCMNTA 391 C+ NL L NG C A GY C C GF G C+ I E P +C G C N Sbjct: 1408 CSENLNLCGNGQCLNA--PGGYRCECDMGFVPSADGKACEDIDECSLPNICVFGTCHNLP 1465 Query: 392 DSYKCACPVTY----TGKNC 439 ++C C + Y +G NC Sbjct: 1466 GLFRCECEIGYELDRSGGNC 1485 Score = 44.8 bits (101), Expect = 2e-04 Identities = 26/70 (37%), Positives = 35/70 (50%), Gaps = 6/70 (8%) Frame = +2 Query: 233 PNLCLNNGVCQEALTEHGYVCLCAPGFG----GNNCDRIGESCR--PGLCGPGKCMNTAD 394 P+LC +G C+ + + C C GF NC I E CR P LCG G+C+NT Sbjct: 1036 PSLC-THGKCRNTIGS--FKCRCDSGFALDSEERNCTDIDE-CRISPDLCGRGQCVNTPG 1091 Query: 395 SYKCACPVTY 424 ++C C Y Sbjct: 1092 DFECKCDEGY 1101 Score = 44.4 bits (100), Expect = 3e-04 Identities = 24/66 (36%), Positives = 32/66 (48%), Gaps = 3/66 (4%) Frame = +2 Query: 236 NLCLNNGVCQEALTEHGYVCLCAPGFGGN---NCDRIGESCRPGLCGPGKCMNTADSYKC 406 N C NG C+ + G+ C C GF C+ I E + L +C+NT SY+C Sbjct: 2174 NPC-GNGTCKNVIG--GFECTCEEGFEPGPMMTCEDINECAQNPLLCAFRCVNTYGSYEC 2230 Query: 407 ACPVTY 424 CPV Y Sbjct: 2231 KCPVGY 2236 Score = 44.0 bits (99), Expect = 3e-04 Identities = 26/72 (36%), Positives = 34/72 (47%), Gaps = 5/72 (6%) Frame = +2 Query: 233 PNLCLNNGVCQEALTEHGYVCLCAPGFGGNN----CDRIGE-SCRPGLCGPGKCMNTADS 397 PN+C + G C E Y CLC GF + C + E P +C G C NT S Sbjct: 1246 PNIC-DGGQCTNIPGE--YRCLCYDGFMASEDMKTCVDVNECDLNPNICLSGTCENTKGS 1302 Query: 398 YKCACPVTYTGK 433 + C C + Y+GK Sbjct: 1303 FICHCDMGYSGK 1314 Score = 44.0 bits (99), Expect = 3e-04 Identities = 25/64 (39%), Positives = 32/64 (50%), Gaps = 4/64 (6%) Frame = +2 Query: 233 PNLCLNNGVCQEALTEHGYVCLCAPGFGGNN----CDRIGESCRPGLCGPGKCMNTADSY 400 PN+C ++G C + T + CLC GF N+ C I E C CG G C NT S+ Sbjct: 1857 PNIC-SHGQCID--TVGSFYCLCHTGFKTNDDQTMCLDINE-CERDACGNGTCRNTIGSF 1912 Query: 401 KCAC 412 C C Sbjct: 1913 NCRC 1916 Score = 43.6 bits (98), Expect = 4e-04 Identities = 24/66 (36%), Positives = 32/66 (48%), Gaps = 5/66 (7%) Frame = +2 Query: 233 PNLCLNNGVCQEALTEHGYVCLCAPGFG----GNNCDRIGESCRPGL-CGPGKCMNTADS 397 P++C NG+C+ Y C+C G+ G NC I E L C G+C NT S Sbjct: 731 PDIC-PNGICENL--RGTYKCICNSGYEVDSTGKNCVDINECVLNSLLCDNGQCRNTPGS 787 Query: 398 YKCACP 415 + C CP Sbjct: 788 FVCTCP 793 Score = 43.2 bits (97), Expect = 6e-04 Identities = 25/75 (33%), Positives = 33/75 (44%), Gaps = 4/75 (5%) Frame = +2 Query: 203 ENVQNCFTCAPNLCLNNGVCQEALTEHGYVCLCAPGF----GGNNCDRIGESCRPGLCGP 370 E++ C PN+C+ G C + C C G+ G NC + E P C Sbjct: 1445 EDIDEC--SLPNICVF-GTCHNL--PGLFRCECEIGYELDRSGGNCTDVNECLDPTTCIS 1499 Query: 371 GKCMNTADSYKCACP 415 G C+NT SY C CP Sbjct: 1500 GNCVNTPGSYICDCP 1514 Score = 42.7 bits (96), Expect = 8e-04 Identities = 28/76 (36%), Positives = 34/76 (44%), Gaps = 5/76 (6%) Frame = +2 Query: 203 ENVQNCFTCAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNN----CDRIGE-SCRPGLCG 367 ++V C P LC G C T + C C G N C+ I E S PG+C Sbjct: 245 QDVDEC-QAIPGLC-QGGNCIN--TVGSFECKCPAGHKLNEVSQKCEDIDECSTIPGICE 300 Query: 368 PGKCMNTADSYKCACP 415 G+C NT SY C CP Sbjct: 301 GGECTNTVSSYFCKCP 316 Score = 42.3 bits (95), Expect = 0.001 Identities = 31/85 (36%), Positives = 38/85 (44%), Gaps = 8/85 (9%) Frame = +2 Query: 185 ALALEKENVQNCFTC--APNLCLNNGVCQEALTEHGYVCLCAPGFGGN-----NCDRIGE 343 AL E+ N + C +P+LC G C T + C C G+ NC I E Sbjct: 1060 ALDSEERNCTDIDECRISPDLC-GRGQCVN--TPGDFECKCDEGYESGFMMMKNCMDIDE 1116 Query: 344 SCR-PGLCGPGKCMNTADSYKCACP 415 R P LC G C NT SY+C CP Sbjct: 1117 CQRDPLLCRGGVCHNTEGSYRCECP 1141 Score = 41.9 bits (94), Expect = 0.001 Identities = 22/65 (33%), Positives = 31/65 (47%), Gaps = 8/65 (12%) Frame = +2 Query: 242 CLNNG-VCQEAL---TEHGYVCLCAPGF----GGNNCDRIGESCRPGLCGPGKCMNTADS 397 CL NG +C T+ + C+C GF G NC+ + E +C G C+N S Sbjct: 534 CLQNGRICNNGRCINTDGSFHCVCNAGFHVTRDGKNCEDMDECSIRNMCLNGMCINEDGS 593 Query: 398 YKCAC 412 +KC C Sbjct: 594 FKCIC 598 Score = 41.9 bits (94), Expect = 0.001 Identities = 23/67 (34%), Positives = 26/67 (38%), Gaps = 6/67 (8%) Frame = +2 Query: 242 CLNNGVCQEALTE--HGYVCLCAPGF----GGNNCDRIGESCRPGLCGPGKCMNTADSYK 403 C N CQ GY C C G+ N C E +CG C NT SYK Sbjct: 2571 CEGNHRCQHGCQNIIGGYRCSCPQGYLQHYQWNQCVDENECLSAHICGGASCHNTLGSYK 2630 Query: 404 CACPVTY 424 C CP + Sbjct: 2631 CMCPAGF 2637 Score = 41.5 bits (93), Expect = 0.002 Identities = 25/78 (32%), Positives = 36/78 (46%) Frame = +2 Query: 242 CLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLCGPGKCMNTADSYKCACPVT 421 C+N G C + +H CLC G+ G +C + C G G+C+ +CAC Sbjct: 123 CMNGGSCSD---DH---CLCQKGYIGTHCGQ--PVCESGCLNGGRCVAPN---RCACTYG 171 Query: 422 YTGKNCEVKQLIEYPAFT 475 +TG CE + P FT Sbjct: 172 FTGPQCE-RDYRTGPCFT 188 Score = 40.7 bits (91), Expect = 0.003 Identities = 22/61 (36%), Positives = 27/61 (44%), Gaps = 7/61 (11%) Frame = +2 Query: 251 NGVCQEALT--EHGYVCLCAPGFG----GNNCDRIGE-SCRPGLCGPGKCMNTADSYKCA 409 NG C+ T E Y C C PGF +C I E P +C G+C N Y+C Sbjct: 1205 NGGCETFCTNSEGSYECSCQPGFALMPDQRSCTDIDECEDNPNICDGGQCTNIPGEYRCL 1264 Query: 410 C 412 C Sbjct: 1265 C 1265 Score = 40.3 bits (90), Expect = 0.004 Identities = 19/45 (42%), Positives = 25/45 (55%), Gaps = 5/45 (11%) Frame = +2 Query: 296 LCAPGFG---GNNCDRIGESCR--PGLCGPGKCMNTADSYKCACP 415 +C G+ G C+ I E C PG+C G C+NT S+KC CP Sbjct: 895 ICGKGYSRIKGTQCEDIDE-CEVFPGVCKNGLCVNTRGSFKCQCP 938 Score = 40.3 bits (90), Expect = 0.004 Identities = 27/80 (33%), Positives = 37/80 (46%), Gaps = 5/80 (6%) Frame = +2 Query: 206 NVQNCFTCAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNN--CDRIGESCRPG--LCGP- 370 ++ C A N C + VC T + C C+PG+ G+ C + E C G +C Sbjct: 1322 DINECEIGAHN-CGKHAVCTN--TAGSFKCSCSPGWIGDGIKCTDLDE-CSNGTHMCSQH 1377 Query: 371 GKCMNTADSYKCACPVTYTG 430 C NT SY+C C YTG Sbjct: 1378 ADCKNTMGSYRCLCKEGYTG 1397 Score = 39.1 bits (87), Expect = 0.010 Identities = 16/36 (44%), Positives = 22/36 (61%), Gaps = 3/36 (8%) Frame = +2 Query: 341 ESCR-PGLCGPGKCMNTADSYKCACPVTYT--GKNC 439 + C+ P +C G+C+NT SY+C CP YT G C Sbjct: 2129 DECKEPDVCKHGQCINTDGSYRCECPFGYTLAGNEC 2164 Score = 38.7 bits (86), Expect = 0.013 Identities = 26/69 (37%), Positives = 30/69 (43%), Gaps = 5/69 (7%) Frame = +2 Query: 233 PNLCLNNGVCQEALTEHGYVCLCAPGF----GGNNCDRIGE-SCRPGLCGPGKCMNTADS 397 P LC GVC TE Y C C PG + C I E LC G+C+N Sbjct: 1121 PLLC-RGGVCHN--TEGSYRCECPPGHQLSPNISACIDINECELSAHLCPNGRCVNLIGK 1177 Query: 398 YKCACPVTY 424 Y+CAC Y Sbjct: 1178 YQCACNPGY 1186 Score = 37.5 bits (83), Expect = 0.029 Identities = 21/54 (38%), Positives = 27/54 (50%), Gaps = 2/54 (3%) Frame = +2 Query: 305 PGFGGNNCDRIGESCR--PGLCGPGKCMNTADSYKCACPVTYTGKNCEVKQLIE 460 P C + E C+ PGLC G C+NT S++C CP + K EV Q E Sbjct: 237 PNIRTGACQDVDE-CQAIPGLCQGGNCINTVGSFECKCPAGH--KLNEVSQKCE 287 Score = 37.1 bits (82), Expect = 0.039 Identities = 22/61 (36%), Positives = 29/61 (47%), Gaps = 8/61 (13%) Frame = +2 Query: 284 GYVCLCAPGFGGNNCDRIGES-CRP--GLCGP-GKCMNTADSYKCAC----PVTYTGKNC 439 G+ C C PGF ++ I + C LCG G C NT S+ C C + TG +C Sbjct: 2506 GFTCKCPPGFTQHHTSCIDNNECTSDINLCGSKGICQNTPGSFTCECQRGFSLDQTGSSC 2565 Query: 440 E 442 E Sbjct: 2566 E 2566 Score = 36.7 bits (81), Expect = 0.052 Identities = 21/57 (36%), Positives = 25/57 (43%), Gaps = 6/57 (10%) Frame = +2 Query: 287 YVCLCAPGFGGNNCDRIGESCR--PGLCGPGKCMNTADSYKCACPVTY----TGKNC 439 Y LC+ G G + C P +C G C N +YKC C Y TGKNC Sbjct: 707 YQALCSSGPGMTSAGSDINECALDPDICPNGICENLRGTYKCICNSGYEVDSTGKNC 763 Score = 36.7 bits (81), Expect = 0.052 Identities = 24/69 (34%), Positives = 33/69 (47%), Gaps = 5/69 (7%) Frame = +2 Query: 233 PNLCLNNGVCQEALTEHGYVCLCAPGFGGNN----CDRIGESCRPGLCGPG-KCMNTADS 397 P +C NGVC + + C C GF N+ C+ I E +C +C+NTA S Sbjct: 1774 PGVC-ENGVCINMVGS--FRCECPVGFFYNDKLLVCEDIDECQNGPVCQRNAECINTAGS 1830 Query: 398 YKCACPVTY 424 Y+C C Y Sbjct: 1831 YRCDCKPGY 1839 Score = 36.7 bits (81), Expect = 0.052 Identities = 20/62 (32%), Positives = 27/62 (43%), Gaps = 2/62 (3%) Frame = +2 Query: 233 PNLCLNNGVCQEALTEHGYVCLCAPGF--GGNNCDRIGESCRPGLCGPGKCMNTADSYKC 406 P++C +G C T+ Y C C G+ GN C E CG G C N ++C Sbjct: 2134 PDVC-KHGQCIN--TDGSYRCECPFGYTLAGNECVDTDECSVGNPCGNGTCKNVIGGFEC 2190 Query: 407 AC 412 C Sbjct: 2191 TC 2192 Score = 35.5 bits (78), Expect = 0.12 Identities = 13/30 (43%), Positives = 19/30 (63%), Gaps = 2/30 (6%) Frame = +2 Query: 341 ESCR--PGLCGPGKCMNTADSYKCACPVTY 424 + CR PG+C G C+N S++C CPV + Sbjct: 1768 DECREIPGVCENGVCINMVGSFRCECPVGF 1797 Score = 35.1 bits (77), Expect = 0.16 Identities = 23/65 (35%), Positives = 26/65 (40%), Gaps = 3/65 (4%) Frame = +2 Query: 239 LCLNNGVCQEALTEHGYVCLCAPGFG---GNNCDRIGESCRPGLCGPGKCMNTADSYKCA 409 LC NG C T Y C C GF C + E C C G+C+N SY C Sbjct: 459 LC-QNGRCIP--TPGSYRCECNKGFQLDLRGECIDVDE-CEKNPCAGGECINNQGSYTCQ 514 Query: 410 CPVTY 424 C Y Sbjct: 515 CRAGY 519 Score = 35.1 bits (77), Expect = 0.16 Identities = 21/63 (33%), Positives = 28/63 (44%), Gaps = 4/63 (6%) Frame = +2 Query: 236 NLCLNNGVCQEALTEHGYVCLCAPGF----GGNNCDRIGESCRPGLCGPGKCMNTADSYK 403 +L +NG C+ T +VC C GF C+ I E C C G C N+ S+ Sbjct: 773 SLLCDNGQCRN--TPGSFVCTCPKGFIYKPDLKTCEDIDE-CESSPCINGVCKNSPGSFI 829 Query: 404 CAC 412 C C Sbjct: 830 CEC 832 Score = 33.9 bits (74), Expect = 0.36 Identities = 23/71 (32%), Positives = 27/71 (38%), Gaps = 8/71 (11%) Frame = +2 Query: 236 NLCLNNGVCQEALTEH---GYVCLCAPGFG----GNNCDRIGE-SCRPGLCGPGKCMNTA 391 N CL+ +C A + Y C+C GF C I E C G C NT Sbjct: 2609 NECLSAHICGGASCHNTLGSYKCMCPAGFQYEQFSGGCQDINECGSAQAPCSYG-CSNTE 2667 Query: 392 DSYKCACPVTY 424 Y C CP Y Sbjct: 2668 GGYLCGCPPGY 2678 Score = 33.5 bits (73), Expect = 0.48 Identities = 24/74 (32%), Positives = 37/74 (50%), Gaps = 12/74 (16%) Frame = +2 Query: 257 VCQ--EALTEHG-YVCLCAPGFG----GNNCDRIGESCR-PGLCGPGKCMNTADSYKCAC 412 VC+ E + + G Y C+C G+ G +C + E + P C C NT SY+C+C Sbjct: 2412 VCRNGECVNDRGSYHCICKTGYTPDITGTSCVDLNECNQAPKPCN-FICKNTEGSYQCSC 2470 Query: 413 PVTY----TGKNCE 442 P Y G++C+ Sbjct: 2471 PKGYILQEDGRSCK 2484 Score = 33.5 bits (73), Expect = 0.48 Identities = 21/70 (30%), Positives = 29/70 (41%), Gaps = 4/70 (5%) Frame = +2 Query: 230 APNLCLNNGVCQEALTEHGYVCLCAPGF----GGNNCDRIGESCRPGLCGPGKCMNTADS 397 AP C N +C+ TE Y C C G+ G +C + E C+NT Sbjct: 2451 APKPC--NFICKN--TEGSYQCSCPKGYILQEDGRSCKDLDECATKQHNCQFLCVNTIGG 2506 Query: 398 YKCACPVTYT 427 + C CP +T Sbjct: 2507 FTCKCPPGFT 2516 Score = 29.9 bits (64), Expect = 5.9 Identities = 15/46 (32%), Positives = 19/46 (41%) Frame = +2 Query: 290 VCLCAPGFGGNNCDRIGESCRPGLCGPGKCMNTADSYKCACPVTYT 427 +C GF N D +C G+C+N SY C C YT Sbjct: 2389 LCPHGRGFMTNGADIDECKVIHDVCRNGECVNDRGSYHCICKTGYT 2434 Score = 29.5 bits (63), Expect = 7.8 Identities = 20/65 (30%), Positives = 27/65 (41%), Gaps = 4/65 (6%) Frame = +2 Query: 203 ENVQNCFTCAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLC----GP 370 E++ C T P +C G C ++ Y C C PGF + RPG C Sbjct: 287 EDIDECSTI-PGIC-EGGECTNTVSS--YFCKCPPGFYTSPDGTRCIDVRPGYCYTALTN 342 Query: 371 GKCMN 385 G+C N Sbjct: 343 GRCSN 347 >BC126986-1|AAI26987.1| 393|Homo sapiens FLJ37440 protein protein. Length = 393 Score = 55.6 bits (128), Expect = 1e-07 Identities = 33/97 (34%), Positives = 44/97 (45%), Gaps = 15/97 (15%) Frame = +2 Query: 197 EKENVQNCFTCAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDR-----------IGE 343 E+ + + C+ C N G C E + + Y C+C PG GN C G+ Sbjct: 130 EQPHCRGISECSSQPCQNGGTCVEGVNQ--YRCICPPGRTGNRCQHQAQTDVNECELYGQ 187 Query: 344 SCRPGLCGPGKCMNTADSYKCACPVTY----TGKNCE 442 RP LC C+NT SY+C CP Y GK+CE Sbjct: 188 EGRPRLCMHA-CVNTPGSYRCTCPGGYRTLADGKSCE 223 Score = 30.3 bits (65), Expect = 4.5 Identities = 21/68 (30%), Positives = 32/68 (47%), Gaps = 7/68 (10%) Frame = +2 Query: 233 PNLCLNNGVCQEALTEHGYVCLCAPGF----GGNNCDRIGE--SCRPGLCGPGK-CMNTA 391 P LC++ C T Y C C G+ G +C+ + E +P +C G C+NT Sbjct: 191 PRLCMH--ACVN--TPGSYRCTCPGGYRTLADGKSCEDVDECVGLQP-VCPQGTTCINTG 245 Query: 392 DSYKCACP 415 S++C P Sbjct: 246 GSFQCVSP 253 >BC074907-1|AAH74907.1| 400|Homo sapiens protein Z, vitamin K-dependent plasma glycoprotein protein. Length = 400 Score = 55.6 bits (128), Expect = 1e-07 Identities = 24/68 (35%), Positives = 36/68 (52%), Gaps = 2/68 (2%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLCGPGK--CMNTADSY 400 C CL+NG CQ+++ GY C C+PG+ G+NC+ C P + C+ +SY Sbjct: 91 CISQPCLHNGSCQDSIW--GYTCTCSPGYEGSNCELAKNECHPERTDGCQHFCLPGQESY 148 Query: 401 KCACPVTY 424 C+C Y Sbjct: 149 TCSCAQGY 156 Score = 29.9 bits (64), Expect = 5.9 Identities = 10/25 (40%), Positives = 13/25 (52%) Frame = +2 Query: 371 GKCMNTADSYKCACPVTYTGKNCEV 445 G C ++ Y C C Y G NCE+ Sbjct: 100 GSCQDSIWGYTCTCSPGYEGSNCEL 124 >BC074906-1|AAH74906.1| 400|Homo sapiens protein Z, vitamin K-dependent plasma glycoprotein protein. Length = 400 Score = 55.6 bits (128), Expect = 1e-07 Identities = 24/68 (35%), Positives = 36/68 (52%), Gaps = 2/68 (2%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLCGPGK--CMNTADSY 400 C CL+NG CQ+++ GY C C+PG+ G+NC+ C P + C+ +SY Sbjct: 91 CISQPCLHNGSCQDSIW--GYTCTCSPGYEGSNCELAKNECHPERTDGCQHFCLPGQESY 148 Query: 401 KCACPVTY 424 C+C Y Sbjct: 149 TCSCAQGY 156 Score = 29.9 bits (64), Expect = 5.9 Identities = 10/25 (40%), Positives = 13/25 (52%) Frame = +2 Query: 371 GKCMNTADSYKCACPVTYTGKNCEV 445 G C ++ Y C C Y G NCE+ Sbjct: 100 GSCQDSIWGYTCTCSPGYEGSNCEL 124 >AL137002-16|CAI41388.1| 400|Homo sapiens protein Z, vitamin K-dependent plasma glycoprotein protein. Length = 400 Score = 55.6 bits (128), Expect = 1e-07 Identities = 24/68 (35%), Positives = 36/68 (52%), Gaps = 2/68 (2%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLCGPGK--CMNTADSY 400 C CL+NG CQ+++ GY C C+PG+ G+NC+ C P + C+ +SY Sbjct: 91 CISQPCLHNGSCQDSIW--GYTCTCSPGYEGSNCELAKNECHPERTDGCQHFCLPGQESY 148 Query: 401 KCACPVTY 424 C+C Y Sbjct: 149 TCSCAQGY 156 Score = 29.9 bits (64), Expect = 5.9 Identities = 10/25 (40%), Positives = 13/25 (52%) Frame = +2 Query: 371 GKCMNTADSYKCACPVTYTGKNCEV 445 G C ++ Y C C Y G NCE+ Sbjct: 100 GSCQDSIWGYTCTCSPGYEGSNCEL 124 >AL137002-15|CAI41389.1| 422|Homo sapiens protein Z, vitamin K-dependent plasma glycoprotein protein. Length = 422 Score = 55.6 bits (128), Expect = 1e-07 Identities = 24/68 (35%), Positives = 36/68 (52%), Gaps = 2/68 (2%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLCGPGK--CMNTADSY 400 C CL+NG CQ+++ GY C C+PG+ G+NC+ C P + C+ +SY Sbjct: 113 CISQPCLHNGSCQDSIW--GYTCTCSPGYEGSNCELAKNECHPERTDGCQHFCLPGQESY 170 Query: 401 KCACPVTY 424 C+C Y Sbjct: 171 TCSCAQGY 178 Score = 29.9 bits (64), Expect = 5.9 Identities = 10/25 (40%), Positives = 13/25 (52%) Frame = +2 Query: 371 GKCMNTADSYKCACPVTYTGKNCEV 445 G C ++ Y C C Y G NCE+ Sbjct: 122 GSCQDSIWGYTCTCSPGYEGSNCEL 146 >AF440358-1|AAL27631.1| 400|Homo sapiens protein Z, vitamin K-dependent plasma glycoprotein protein. Length = 400 Score = 55.6 bits (128), Expect = 1e-07 Identities = 24/68 (35%), Positives = 36/68 (52%), Gaps = 2/68 (2%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLCGPGK--CMNTADSY 400 C CL+NG CQ+++ GY C C+PG+ G+NC+ C P + C+ +SY Sbjct: 91 CISQPCLHNGSCQDSIW--GYTCTCSPGYEGSNCELAKNECHPERTDGCQHFCLPGQESY 148 Query: 401 KCACPVTY 424 C+C Y Sbjct: 149 TCSCAQGY 156 Score = 29.9 bits (64), Expect = 5.9 Identities = 10/25 (40%), Positives = 13/25 (52%) Frame = +2 Query: 371 GKCMNTADSYKCACPVTYTGKNCEV 445 G C ++ Y C C Y G NCE+ Sbjct: 100 GSCQDSIWGYTCTCSPGYEGSNCEL 124 >AB177803-1|BAD16739.1| 2871|Homo sapiens fibrillin 1 protein. Length = 2871 Score = 55.6 bits (128), Expect = 1e-07 Identities = 30/76 (39%), Positives = 43/76 (56%), Gaps = 6/76 (7%) Frame = +2 Query: 203 ENVQNCFTCA-PNLCLNNGVCQEALTEHG-YVCLCAPGF----GGNNCDRIGESCRPGLC 364 +N ++ C+ N+CLN G+C + E G + C+C PGF G C I E PG+C Sbjct: 568 KNCEDMDECSIRNMCLN-GMC---INEDGSFKCICKPGFQLASDGRYCKDINECETPGIC 623 Query: 365 GPGKCMNTADSYKCAC 412 G+C+NT SY+C C Sbjct: 624 MNGRCVNTDGSYRCEC 639 Score = 55.2 bits (127), Expect = 1e-07 Identities = 32/87 (36%), Positives = 39/87 (44%), Gaps = 8/87 (9%) Frame = +2 Query: 203 ENVQNCFTCAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNN----CDRIGESCRPGLCGP 370 E++ C P LC G C T + C C G+ N CD + E PG+CGP Sbjct: 1605 EDIDECQEL-PGLC-QGGKCIN--TFGSFQCRCPTGYYLNEDTRVCDDVNECETPGICGP 1660 Query: 371 GKCMNTADSYKCACPVTYT----GKNC 439 G C NT +Y C CP Y G NC Sbjct: 1661 GTCYNTVGNYTCICPPDYMQVNGGNNC 1687 Score = 50.0 bits (114), Expect = 5e-06 Identities = 33/95 (34%), Positives = 43/95 (45%), Gaps = 8/95 (8%) Frame = +2 Query: 206 NVQNCFTCAPNLCLNNGVCQEALTEHGYVCLCAPGF----GGNNCDRIGESC-RPGLCGP 370 +V C + NLC NG C T + C C G+ G C I E P C P Sbjct: 1930 DVDECASGNGNLC-RNGQCIN--TVGSFQCQCNEGYEVAPDGRTCVDINECLLEPRKCAP 1986 Query: 371 GKCMNTADSYKCACPVTYTGKN--CE-VKQLIEYP 466 G C N SY+C CP Y+ +N CE + + +E P Sbjct: 1987 GTCQNLDGSYRCICPPGYSLQNEKCEDIDECVEEP 2021 Score = 49.6 bits (113), Expect = 7e-06 Identities = 28/83 (33%), Positives = 41/83 (49%), Gaps = 8/83 (9%) Frame = +2 Query: 254 GVCQEALTEHGYVCLCAPGFGGNN--CDRIGESCR-PGLCGPGKCMNTADSYKCACP--- 415 G CQ + Y C+C PG+ N C+ I E P +C G C NT S+KC CP Sbjct: 1987 GTCQNL--DGSYRCICPPGYSLQNEKCEDIDECVEEPEICALGTCSNTEGSFKCLCPEGF 2044 Query: 416 -VTYTGKNC-EVKQLIEYPAFTG 478 ++ +G+ C +++ Y F G Sbjct: 2045 SLSSSGRRCQDLRMSYCYAKFEG 2067 Score = 46.0 bits (104), Expect = 8e-05 Identities = 29/83 (34%), Positives = 40/83 (48%), Gaps = 7/83 (8%) Frame = +2 Query: 233 PNLCLNNGVCQEALTEHGYVCLCAPGFGGNN----CDRIGESCRPGLCGPGK---CMNTA 391 PN+CL+ G C+ T+ ++C C G+ G C I E C G GK C NTA Sbjct: 1288 PNICLS-GTCEN--TKGSFICHCDMGYSGKKGKTGCTDINE-CEIGAHNCGKHAVCTNTA 1343 Query: 392 DSYKCACPVTYTGKNCEVKQLIE 460 S+KC+C + G + L E Sbjct: 1344 GSFKCSCSPGWIGDGIKCTDLDE 1366 Score = 46.0 bits (104), Expect = 8e-05 Identities = 20/52 (38%), Positives = 28/52 (53%), Gaps = 5/52 (9%) Frame = +2 Query: 287 YVCLCAPGF----GGNNCDRIGE-SCRPGLCGPGKCMNTADSYKCACPVTYT 427 Y+C+C PG+ G C E +PG+C G+C+NT SY C C +T Sbjct: 2272 YMCICGPGYQRRPDGEGCVDENECQTKPGICENGRCLNTRGSYTCECNDGFT 2323 Score = 45.2 bits (102), Expect = 1e-04 Identities = 29/80 (36%), Positives = 36/80 (45%), Gaps = 9/80 (11%) Frame = +2 Query: 227 CAPNLCL-NNGVCQEALTEHGYVCLCAPGF----GGNNCDRIGESCRPGLCGPGKCMNTA 391 C+ NL L NG C A GY C C GF G C+ I E P +C G C N Sbjct: 1408 CSENLNLCGNGQCLNA--PGGYRCECDMGFVPSADGKACEDIDECSLPNICVFGTCHNLP 1465 Query: 392 DSYKCACPVTY----TGKNC 439 ++C C + Y +G NC Sbjct: 1466 GLFRCECEIGYELDRSGGNC 1485 Score = 44.8 bits (101), Expect = 2e-04 Identities = 26/70 (37%), Positives = 35/70 (50%), Gaps = 6/70 (8%) Frame = +2 Query: 233 PNLCLNNGVCQEALTEHGYVCLCAPGFG----GNNCDRIGESCR--PGLCGPGKCMNTAD 394 P+LC +G C+ + + C C GF NC I E CR P LCG G+C+NT Sbjct: 1036 PSLC-THGKCRNTIGS--FKCRCDSGFALDSEERNCTDIDE-CRISPDLCGRGQCVNTPG 1091 Query: 395 SYKCACPVTY 424 ++C C Y Sbjct: 1092 DFECKCDEGY 1101 Score = 44.4 bits (100), Expect = 3e-04 Identities = 24/66 (36%), Positives = 32/66 (48%), Gaps = 3/66 (4%) Frame = +2 Query: 236 NLCLNNGVCQEALTEHGYVCLCAPGFGGN---NCDRIGESCRPGLCGPGKCMNTADSYKC 406 N C NG C+ + G+ C C GF C+ I E + L +C+NT SY+C Sbjct: 2174 NPC-GNGTCKNVIG--GFECTCEEGFEPGPMMTCEDINECAQNPLLCAFRCVNTYGSYEC 2230 Query: 407 ACPVTY 424 CPV Y Sbjct: 2231 KCPVGY 2236 Score = 44.0 bits (99), Expect = 3e-04 Identities = 26/72 (36%), Positives = 34/72 (47%), Gaps = 5/72 (6%) Frame = +2 Query: 233 PNLCLNNGVCQEALTEHGYVCLCAPGFGGNN----CDRIGE-SCRPGLCGPGKCMNTADS 397 PN+C + G C E Y CLC GF + C + E P +C G C NT S Sbjct: 1246 PNIC-DGGQCTNIPGE--YRCLCYDGFMASEDMKTCVDVNECDLNPNICLSGTCENTKGS 1302 Query: 398 YKCACPVTYTGK 433 + C C + Y+GK Sbjct: 1303 FICHCDMGYSGK 1314 Score = 44.0 bits (99), Expect = 3e-04 Identities = 25/64 (39%), Positives = 32/64 (50%), Gaps = 4/64 (6%) Frame = +2 Query: 233 PNLCLNNGVCQEALTEHGYVCLCAPGFGGNN----CDRIGESCRPGLCGPGKCMNTADSY 400 PN+C ++G C + T + CLC GF N+ C I E C CG G C NT S+ Sbjct: 1857 PNIC-SHGQCID--TVGSFYCLCHTGFKTNDDQTMCLDINE-CERDACGNGTCRNTIGSF 1912 Query: 401 KCAC 412 C C Sbjct: 1913 NCRC 1916 Score = 43.6 bits (98), Expect = 4e-04 Identities = 24/66 (36%), Positives = 32/66 (48%), Gaps = 5/66 (7%) Frame = +2 Query: 233 PNLCLNNGVCQEALTEHGYVCLCAPGFG----GNNCDRIGESCRPGL-CGPGKCMNTADS 397 P++C NG+C+ Y C+C G+ G NC I E L C G+C NT S Sbjct: 731 PDIC-PNGICENL--RGTYKCICNSGYEVDSTGKNCVDINECVLNSLLCDNGQCRNTPGS 787 Query: 398 YKCACP 415 + C CP Sbjct: 788 FVCTCP 793 Score = 43.2 bits (97), Expect = 6e-04 Identities = 25/75 (33%), Positives = 33/75 (44%), Gaps = 4/75 (5%) Frame = +2 Query: 203 ENVQNCFTCAPNLCLNNGVCQEALTEHGYVCLCAPGF----GGNNCDRIGESCRPGLCGP 370 E++ C PN+C+ G C + C C G+ G NC + E P C Sbjct: 1445 EDIDEC--SLPNICVF-GTCHNL--PGLFRCECEIGYELDRSGGNCTDVNECLDPTTCIS 1499 Query: 371 GKCMNTADSYKCACP 415 G C+NT SY C CP Sbjct: 1500 GNCVNTPGSYICDCP 1514 Score = 42.7 bits (96), Expect = 8e-04 Identities = 28/76 (36%), Positives = 34/76 (44%), Gaps = 5/76 (6%) Frame = +2 Query: 203 ENVQNCFTCAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNN----CDRIGE-SCRPGLCG 367 ++V C P LC G C T + C C G N C+ I E S PG+C Sbjct: 245 QDVDEC-QAIPGLC-QGGNCIN--TVGSFECKCPAGHKLNEVSQKCEDIDECSTIPGICE 300 Query: 368 PGKCMNTADSYKCACP 415 G+C NT SY C CP Sbjct: 301 GGECTNTVSSYFCKCP 316 Score = 42.3 bits (95), Expect = 0.001 Identities = 31/85 (36%), Positives = 38/85 (44%), Gaps = 8/85 (9%) Frame = +2 Query: 185 ALALEKENVQNCFTC--APNLCLNNGVCQEALTEHGYVCLCAPGFGGN-----NCDRIGE 343 AL E+ N + C +P+LC G C T + C C G+ NC I E Sbjct: 1060 ALDSEERNCTDIDECRISPDLC-GRGQCVN--TPGDFECKCDEGYESGFMMMKNCMDIDE 1116 Query: 344 SCR-PGLCGPGKCMNTADSYKCACP 415 R P LC G C NT SY+C CP Sbjct: 1117 CQRDPLLCRGGVCHNTEGSYRCECP 1141 Score = 41.9 bits (94), Expect = 0.001 Identities = 22/65 (33%), Positives = 31/65 (47%), Gaps = 8/65 (12%) Frame = +2 Query: 242 CLNNG-VCQEAL---TEHGYVCLCAPGF----GGNNCDRIGESCRPGLCGPGKCMNTADS 397 CL NG +C T+ + C+C GF G NC+ + E +C G C+N S Sbjct: 534 CLQNGRICNNGRCINTDGSFHCVCNAGFHVTRDGKNCEDMDECSIRNMCLNGMCINEDGS 593 Query: 398 YKCAC 412 +KC C Sbjct: 594 FKCIC 598 Score = 41.9 bits (94), Expect = 0.001 Identities = 23/67 (34%), Positives = 26/67 (38%), Gaps = 6/67 (8%) Frame = +2 Query: 242 CLNNGVCQEALTE--HGYVCLCAPGF----GGNNCDRIGESCRPGLCGPGKCMNTADSYK 403 C N CQ GY C C G+ N C E +CG C NT SYK Sbjct: 2571 CEGNHRCQHGCQNIIGGYRCSCPQGYLQHYQWNQCVDENECLSAHICGGASCHNTLGSYK 2630 Query: 404 CACPVTY 424 C CP + Sbjct: 2631 CMCPAGF 2637 Score = 41.5 bits (93), Expect = 0.002 Identities = 25/78 (32%), Positives = 36/78 (46%) Frame = +2 Query: 242 CLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLCGPGKCMNTADSYKCACPVT 421 C+N G C + +H CLC G+ G +C + C G G+C+ +CAC Sbjct: 123 CMNGGSCSD---DH---CLCQKGYIGTHCGQ--PVCESGCLNGGRCVAPN---RCACTYG 171 Query: 422 YTGKNCEVKQLIEYPAFT 475 +TG CE + P FT Sbjct: 172 FTGPQCE-RDYRTGPCFT 188 Score = 40.7 bits (91), Expect = 0.003 Identities = 22/61 (36%), Positives = 27/61 (44%), Gaps = 7/61 (11%) Frame = +2 Query: 251 NGVCQEALT--EHGYVCLCAPGFG----GNNCDRIGE-SCRPGLCGPGKCMNTADSYKCA 409 NG C+ T E Y C C PGF +C I E P +C G+C N Y+C Sbjct: 1205 NGGCETFCTNSEGSYECSCQPGFALMPDQRSCTDIDECEDNPNICDGGQCTNIPGEYRCL 1264 Query: 410 C 412 C Sbjct: 1265 C 1265 Score = 40.3 bits (90), Expect = 0.004 Identities = 19/45 (42%), Positives = 25/45 (55%), Gaps = 5/45 (11%) Frame = +2 Query: 296 LCAPGFG---GNNCDRIGESCR--PGLCGPGKCMNTADSYKCACP 415 +C G+ G C+ I E C PG+C G C+NT S+KC CP Sbjct: 895 ICGKGYSRIKGTQCEDIDE-CEVFPGVCKNGLCVNTRGSFKCQCP 938 Score = 40.3 bits (90), Expect = 0.004 Identities = 27/80 (33%), Positives = 37/80 (46%), Gaps = 5/80 (6%) Frame = +2 Query: 206 NVQNCFTCAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNN--CDRIGESCRPG--LCGP- 370 ++ C A N C + VC T + C C+PG+ G+ C + E C G +C Sbjct: 1322 DINECEIGAHN-CGKHAVCTN--TAGSFKCSCSPGWIGDGIKCTDLDE-CSNGTHMCSQH 1377 Query: 371 GKCMNTADSYKCACPVTYTG 430 C NT SY+C C YTG Sbjct: 1378 ADCKNTMGSYRCLCKEGYTG 1397 Score = 38.7 bits (86), Expect = 0.013 Identities = 26/69 (37%), Positives = 30/69 (43%), Gaps = 5/69 (7%) Frame = +2 Query: 233 PNLCLNNGVCQEALTEHGYVCLCAPGF----GGNNCDRIGE-SCRPGLCGPGKCMNTADS 397 P LC GVC TE Y C C PG + C I E LC G+C+N Sbjct: 1121 PLLC-RGGVCHN--TEGSYRCECPPGHQLSPNISACIDINECELSAHLCPNGRCVNLIGK 1177 Query: 398 YKCACPVTY 424 Y+CAC Y Sbjct: 1178 YQCACNPGY 1186 Score = 37.5 bits (83), Expect = 0.029 Identities = 21/54 (38%), Positives = 27/54 (50%), Gaps = 2/54 (3%) Frame = +2 Query: 305 PGFGGNNCDRIGESCR--PGLCGPGKCMNTADSYKCACPVTYTGKNCEVKQLIE 460 P C + E C+ PGLC G C+NT S++C CP + K EV Q E Sbjct: 237 PNIRTGACQDVDE-CQAIPGLCQGGNCINTVGSFECKCPAGH--KLNEVSQKCE 287 Score = 37.1 bits (82), Expect = 0.039 Identities = 15/36 (41%), Positives = 21/36 (58%), Gaps = 3/36 (8%) Frame = +2 Query: 341 ESCR-PGLCGPGKCMNTADSYKCACPVTY--TGKNC 439 + C+ P +C G+C+NT SY+C CP Y G C Sbjct: 2129 DECKEPDVCKHGQCINTDGSYRCECPFGYILAGNEC 2164 Score = 37.1 bits (82), Expect = 0.039 Identities = 22/61 (36%), Positives = 29/61 (47%), Gaps = 8/61 (13%) Frame = +2 Query: 284 GYVCLCAPGFGGNNCDRIGES-CRP--GLCGP-GKCMNTADSYKCAC----PVTYTGKNC 439 G+ C C PGF ++ I + C LCG G C NT S+ C C + TG +C Sbjct: 2506 GFTCKCPPGFTQHHTSCIDNNECTSDINLCGSKGICQNTPGSFTCECQRGFSLDQTGSSC 2565 Query: 440 E 442 E Sbjct: 2566 E 2566 Score = 36.7 bits (81), Expect = 0.052 Identities = 21/57 (36%), Positives = 25/57 (43%), Gaps = 6/57 (10%) Frame = +2 Query: 287 YVCLCAPGFGGNNCDRIGESCR--PGLCGPGKCMNTADSYKCACPVTY----TGKNC 439 Y LC+ G G + C P +C G C N +YKC C Y TGKNC Sbjct: 707 YQALCSSGPGMTSAGSDINECALDPDICPNGICENLRGTYKCICNSGYEVDSTGKNC 763 Score = 36.7 bits (81), Expect = 0.052 Identities = 24/69 (34%), Positives = 33/69 (47%), Gaps = 5/69 (7%) Frame = +2 Query: 233 PNLCLNNGVCQEALTEHGYVCLCAPGFGGNN----CDRIGESCRPGLCGPG-KCMNTADS 397 P +C NGVC + + C C GF N+ C+ I E +C +C+NTA S Sbjct: 1774 PGVC-ENGVCINMVGS--FRCECPVGFFYNDKLLVCEDIDECQNGPVCQRNAECINTAGS 1830 Query: 398 YKCACPVTY 424 Y+C C Y Sbjct: 1831 YRCDCKPGY 1839 Score = 36.7 bits (81), Expect = 0.052 Identities = 20/62 (32%), Positives = 27/62 (43%), Gaps = 2/62 (3%) Frame = +2 Query: 233 PNLCLNNGVCQEALTEHGYVCLCAPGF--GGNNCDRIGESCRPGLCGPGKCMNTADSYKC 406 P++C +G C T+ Y C C G+ GN C E CG G C N ++C Sbjct: 2134 PDVC-KHGQCIN--TDGSYRCECPFGYILAGNECVDTDECSVGNPCGNGTCKNVIGGFEC 2190 Query: 407 AC 412 C Sbjct: 2191 TC 2192 Score = 35.5 bits (78), Expect = 0.12 Identities = 13/30 (43%), Positives = 19/30 (63%), Gaps = 2/30 (6%) Frame = +2 Query: 341 ESCR--PGLCGPGKCMNTADSYKCACPVTY 424 + CR PG+C G C+N S++C CPV + Sbjct: 1768 DECREIPGVCENGVCINMVGSFRCECPVGF 1797 Score = 35.1 bits (77), Expect = 0.16 Identities = 21/63 (33%), Positives = 28/63 (44%), Gaps = 4/63 (6%) Frame = +2 Query: 236 NLCLNNGVCQEALTEHGYVCLCAPGF----GGNNCDRIGESCRPGLCGPGKCMNTADSYK 403 +L +NG C+ T +VC C GF C+ I E C C G C N+ S+ Sbjct: 773 SLLCDNGQCRN--TPGSFVCTCPKGFIYKPDLKTCEDIDE-CESSPCINGVCKNSPGSFI 829 Query: 404 CAC 412 C C Sbjct: 830 CEC 832 Score = 33.5 bits (73), Expect = 0.48 Identities = 24/74 (32%), Positives = 37/74 (50%), Gaps = 12/74 (16%) Frame = +2 Query: 257 VCQ--EALTEHG-YVCLCAPGFG----GNNCDRIGESCR-PGLCGPGKCMNTADSYKCAC 412 VC+ E + + G Y C+C G+ G +C + E + P C C NT SY+C+C Sbjct: 2412 VCRNGECVNDRGSYHCICKTGYTPDITGTSCVDLNECNQAPKPCN-FICKNTEGSYQCSC 2470 Query: 413 PVTY----TGKNCE 442 P Y G++C+ Sbjct: 2471 PKGYILQEDGRSCK 2484 Score = 33.5 bits (73), Expect = 0.48 Identities = 21/70 (30%), Positives = 29/70 (41%), Gaps = 4/70 (5%) Frame = +2 Query: 230 APNLCLNNGVCQEALTEHGYVCLCAPGF----GGNNCDRIGESCRPGLCGPGKCMNTADS 397 AP C N +C+ TE Y C C G+ G +C + E C+NT Sbjct: 2451 APKPC--NFICKN--TEGSYQCSCPKGYILQEDGRSCKDLDECATKQHNCQFLCVNTIGG 2506 Query: 398 YKCACPVTYT 427 + C CP +T Sbjct: 2507 FTCKCPPGFT 2516 Score = 31.5 bits (68), Expect = 1.9 Identities = 16/47 (34%), Positives = 19/47 (40%), Gaps = 3/47 (6%) Frame = +2 Query: 293 CLCAPGFG---GNNCDRIGESCRPGLCGPGKCMNTADSYKCACPVTY 424 C C GF C + E C C G+C+N SY C C Y Sbjct: 474 CECNKGFQLDLRGECIDVDE-CEKNPCAGGECINNQGSYTCQCRAGY 519 Score = 30.3 bits (65), Expect = 4.5 Identities = 22/71 (30%), Positives = 26/71 (36%), Gaps = 8/71 (11%) Frame = +2 Query: 236 NLCLNNGVCQEALTEH---GYVCLCAPGFG----GNNCDRIGE-SCRPGLCGPGKCMNTA 391 N CL+ +C A + Y C+C GF C I E C G NT Sbjct: 2609 NECLSAHICGGASCHNTLGSYKCMCPAGFQYEQFSGGCQDINECGSAQAPCSYGSS-NTE 2667 Query: 392 DSYKCACPVTY 424 Y C CP Y Sbjct: 2668 GGYLCGCPPGY 2678 Score = 29.9 bits (64), Expect = 5.9 Identities = 15/46 (32%), Positives = 19/46 (41%) Frame = +2 Query: 290 VCLCAPGFGGNNCDRIGESCRPGLCGPGKCMNTADSYKCACPVTYT 427 +C GF N D +C G+C+N SY C C YT Sbjct: 2389 LCPHGRGFMTNGADIDECKVIHDVCRNGECVNDRGSYHCICKTGYT 2434 Score = 29.5 bits (63), Expect = 7.8 Identities = 20/65 (30%), Positives = 27/65 (41%), Gaps = 4/65 (6%) Frame = +2 Query: 203 ENVQNCFTCAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLC----GP 370 E++ C T P +C G C ++ Y C C PGF + RPG C Sbjct: 287 EDIDECSTI-PGIC-EGGECTNTVSS--YFCKCPPGFYTSPDGTRCIDVRPGYCYTALTN 342 Query: 371 GKCMN 385 G+C N Sbjct: 343 GRCSN 347 >AB177802-1|BAD16738.1| 1365|Homo sapiens fibrillin 1 protein. Length = 1365 Score = 55.6 bits (128), Expect = 1e-07 Identities = 30/76 (39%), Positives = 43/76 (56%), Gaps = 6/76 (7%) Frame = +2 Query: 203 ENVQNCFTCA-PNLCLNNGVCQEALTEHG-YVCLCAPGF----GGNNCDRIGESCRPGLC 364 +N ++ C+ N+CLN G+C + E G + C+C PGF G C I E PG+C Sbjct: 568 KNCEDMDECSIRNMCLN-GMC---INEDGSFKCICKPGFQLASDGRYCKDINECETPGIC 623 Query: 365 GPGKCMNTADSYKCAC 412 G+C+NT SY+C C Sbjct: 624 MNGRCVNTDGSYRCEC 639 Score = 45.2 bits (102), Expect = 1e-04 Identities = 28/81 (34%), Positives = 39/81 (48%), Gaps = 7/81 (8%) Frame = +2 Query: 233 PNLCLNNGVCQEALTEHGYVCLCAPGFGGNN----CDRIGESCRPGLCGPGK---CMNTA 391 PN+CL+ G C+ T+ ++C C G+ G C I E C G GK C NTA Sbjct: 1288 PNICLS-GTCEN--TKGSFICHCDMGYSGKKGKTGCTDINE-CEIGAHNCGKHAVCTNTA 1343 Query: 392 DSYKCACPVTYTGKNCEVKQL 454 S+KC+C + G + L Sbjct: 1344 GSFKCSCSPGWIGDGIKCTDL 1364 Score = 44.8 bits (101), Expect = 2e-04 Identities = 26/70 (37%), Positives = 35/70 (50%), Gaps = 6/70 (8%) Frame = +2 Query: 233 PNLCLNNGVCQEALTEHGYVCLCAPGFG----GNNCDRIGESCR--PGLCGPGKCMNTAD 394 P+LC +G C+ + + C C GF NC I E CR P LCG G+C+NT Sbjct: 1036 PSLC-THGKCRNTIGS--FKCRCDSGFALDSEERNCTDIDE-CRISPDLCGRGQCVNTPG 1091 Query: 395 SYKCACPVTY 424 ++C C Y Sbjct: 1092 DFECKCDEGY 1101 Score = 44.0 bits (99), Expect = 3e-04 Identities = 26/72 (36%), Positives = 34/72 (47%), Gaps = 5/72 (6%) Frame = +2 Query: 233 PNLCLNNGVCQEALTEHGYVCLCAPGFGGNN----CDRIGE-SCRPGLCGPGKCMNTADS 397 PN+C + G C E Y CLC GF + C + E P +C G C NT S Sbjct: 1246 PNIC-DGGQCTNIPGE--YRCLCYDGFMASEDMKTCVDVNECDLNPNICLSGTCENTKGS 1302 Query: 398 YKCACPVTYTGK 433 + C C + Y+GK Sbjct: 1303 FICHCDMGYSGK 1314 Score = 43.6 bits (98), Expect = 4e-04 Identities = 24/66 (36%), Positives = 32/66 (48%), Gaps = 5/66 (7%) Frame = +2 Query: 233 PNLCLNNGVCQEALTEHGYVCLCAPGFG----GNNCDRIGESCRPGL-CGPGKCMNTADS 397 P++C NG+C+ Y C+C G+ G NC I E L C G+C NT S Sbjct: 731 PDIC-PNGICENL--RGTYKCICNSGYEVDSTGKNCVDINECVLNSLLCDNGQCRNTPGS 787 Query: 398 YKCACP 415 + C CP Sbjct: 788 FVCTCP 793 Score = 42.7 bits (96), Expect = 8e-04 Identities = 28/76 (36%), Positives = 34/76 (44%), Gaps = 5/76 (6%) Frame = +2 Query: 203 ENVQNCFTCAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNN----CDRIGE-SCRPGLCG 367 ++V C P LC G C T + C C G N C+ I E S PG+C Sbjct: 245 QDVDEC-QAIPGLC-QGGNCIN--TVGSFECKCPAGHKLNEVSQKCEDIDECSTIPGICE 300 Query: 368 PGKCMNTADSYKCACP 415 G+C NT SY C CP Sbjct: 301 GGECTNTVSSYFCKCP 316 Score = 42.3 bits (95), Expect = 0.001 Identities = 31/85 (36%), Positives = 38/85 (44%), Gaps = 8/85 (9%) Frame = +2 Query: 185 ALALEKENVQNCFTC--APNLCLNNGVCQEALTEHGYVCLCAPGFGGN-----NCDRIGE 343 AL E+ N + C +P+LC G C T + C C G+ NC I E Sbjct: 1060 ALDSEERNCTDIDECRISPDLC-GRGQCVN--TPGDFECKCDEGYESGFMMMKNCMDIDE 1116 Query: 344 SCR-PGLCGPGKCMNTADSYKCACP 415 R P LC G C NT SY+C CP Sbjct: 1117 CQRDPLLCRGGVCHNTEGSYRCECP 1141 Score = 41.9 bits (94), Expect = 0.001 Identities = 22/65 (33%), Positives = 31/65 (47%), Gaps = 8/65 (12%) Frame = +2 Query: 242 CLNNG-VCQEAL---TEHGYVCLCAPGF----GGNNCDRIGESCRPGLCGPGKCMNTADS 397 CL NG +C T+ + C+C GF G NC+ + E +C G C+N S Sbjct: 534 CLQNGRICNNGRCINTDGSFHCVCNAGFHVTRDGKNCEDMDECSIRNMCLNGMCINEDGS 593 Query: 398 YKCAC 412 +KC C Sbjct: 594 FKCIC 598 Score = 41.5 bits (93), Expect = 0.002 Identities = 25/78 (32%), Positives = 36/78 (46%) Frame = +2 Query: 242 CLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLCGPGKCMNTADSYKCACPVT 421 C+N G C + +H CLC G+ G +C + C G G+C+ +CAC Sbjct: 123 CMNGGSCSD---DH---CLCQKGYIGTHCGQ--PVCESGCLNGGRCVAPN---RCACTYG 171 Query: 422 YTGKNCEVKQLIEYPAFT 475 +TG CE + P FT Sbjct: 172 FTGPQCE-RDYRTGPCFT 188 Score = 40.7 bits (91), Expect = 0.003 Identities = 22/61 (36%), Positives = 27/61 (44%), Gaps = 7/61 (11%) Frame = +2 Query: 251 NGVCQEALT--EHGYVCLCAPGFG----GNNCDRIGE-SCRPGLCGPGKCMNTADSYKCA 409 NG C+ T E Y C C PGF +C I E P +C G+C N Y+C Sbjct: 1205 NGGCETFCTNSEGSYECSCQPGFALMPDQRSCTDIDECEDNPNICDGGQCTNIPGEYRCL 1264 Query: 410 C 412 C Sbjct: 1265 C 1265 Score = 40.3 bits (90), Expect = 0.004 Identities = 19/45 (42%), Positives = 25/45 (55%), Gaps = 5/45 (11%) Frame = +2 Query: 296 LCAPGFG---GNNCDRIGESCR--PGLCGPGKCMNTADSYKCACP 415 +C G+ G C+ I E C PG+C G C+NT S+KC CP Sbjct: 895 ICGKGYSRIKGTQCEDIDE-CEVFPGVCKNGLCVNTRGSFKCQCP 938 Score = 38.7 bits (86), Expect = 0.013 Identities = 26/69 (37%), Positives = 30/69 (43%), Gaps = 5/69 (7%) Frame = +2 Query: 233 PNLCLNNGVCQEALTEHGYVCLCAPGF----GGNNCDRIGE-SCRPGLCGPGKCMNTADS 397 P LC GVC TE Y C C PG + C I E LC G+C+N Sbjct: 1121 PLLC-RGGVCHN--TEGSYRCECPPGHQLSPNISACIDINECELSAHLCPNGRCVNLIGK 1177 Query: 398 YKCACPVTY 424 Y+CAC Y Sbjct: 1178 YQCACNPGY 1186 Score = 37.5 bits (83), Expect = 0.029 Identities = 21/54 (38%), Positives = 27/54 (50%), Gaps = 2/54 (3%) Frame = +2 Query: 305 PGFGGNNCDRIGESCR--PGLCGPGKCMNTADSYKCACPVTYTGKNCEVKQLIE 460 P C + E C+ PGLC G C+NT S++C CP + K EV Q E Sbjct: 237 PNIRTGACQDVDE-CQAIPGLCQGGNCINTVGSFECKCPAGH--KLNEVSQKCE 287 Score = 36.7 bits (81), Expect = 0.052 Identities = 21/57 (36%), Positives = 25/57 (43%), Gaps = 6/57 (10%) Frame = +2 Query: 287 YVCLCAPGFGGNNCDRIGESCR--PGLCGPGKCMNTADSYKCACPVTY----TGKNC 439 Y LC+ G G + C P +C G C N +YKC C Y TGKNC Sbjct: 707 YQALCSSGPGMTSAGSDINECALDPDICPNGICENLRGTYKCICNSGYEVDSTGKNC 763 Score = 35.1 bits (77), Expect = 0.16 Identities = 21/63 (33%), Positives = 28/63 (44%), Gaps = 4/63 (6%) Frame = +2 Query: 236 NLCLNNGVCQEALTEHGYVCLCAPGF----GGNNCDRIGESCRPGLCGPGKCMNTADSYK 403 +L +NG C+ T +VC C GF C+ I E C C G C N+ S+ Sbjct: 773 SLLCDNGQCRN--TPGSFVCTCPKGFIYKPDLKTCEDIDE-CESSPCINGVCKNSPGSFI 829 Query: 404 CAC 412 C C Sbjct: 830 CEC 832 Score = 31.5 bits (68), Expect = 1.9 Identities = 16/47 (34%), Positives = 19/47 (40%), Gaps = 3/47 (6%) Frame = +2 Query: 293 CLCAPGFG---GNNCDRIGESCRPGLCGPGKCMNTADSYKCACPVTY 424 C C GF C + E C C G+C+N SY C C Y Sbjct: 474 CECNKGFQLDLRGECIDVDE-CEKNPCAGGECINNQGSYTCQCRAGY 519 Score = 29.5 bits (63), Expect = 7.8 Identities = 20/65 (30%), Positives = 27/65 (41%), Gaps = 4/65 (6%) Frame = +2 Query: 203 ENVQNCFTCAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLC----GP 370 E++ C T P +C G C ++ Y C C PGF + RPG C Sbjct: 287 EDIDECSTI-PGIC-EGGECTNTVSS--YFCKCPPGFYTSPDGTRCIDVRPGYCYTALTN 342 Query: 371 GKCMN 385 G+C N Sbjct: 343 GRCSN 347 >AB033749-2|BAA85764.1| 422|Homo sapiens protein Z spliced variant protein. Length = 422 Score = 55.6 bits (128), Expect = 1e-07 Identities = 24/68 (35%), Positives = 36/68 (52%), Gaps = 2/68 (2%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLCGPGK--CMNTADSY 400 C CL+NG CQ+++ GY C C+PG+ G+NC+ C P + C+ +SY Sbjct: 113 CISQPCLHNGSCQDSIW--GYTCTCSPGYEGSNCELAKNECHPERTDGCQHFCLPGQESY 170 Query: 401 KCACPVTY 424 C+C Y Sbjct: 171 TCSCAQGY 178 Score = 29.9 bits (64), Expect = 5.9 Identities = 10/25 (40%), Positives = 13/25 (52%) Frame = +2 Query: 371 GKCMNTADSYKCACPVTYTGKNCEV 445 G C ++ Y C C Y G NCE+ Sbjct: 122 GSCQDSIWGYTCTCSPGYEGSNCEL 146 >AB033749-1|BAA85763.1| 400|Homo sapiens protein Z protein. Length = 400 Score = 55.6 bits (128), Expect = 1e-07 Identities = 24/68 (35%), Positives = 36/68 (52%), Gaps = 2/68 (2%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLCGPGK--CMNTADSY 400 C CL+NG CQ+++ GY C C+PG+ G+NC+ C P + C+ +SY Sbjct: 91 CISQPCLHNGSCQDSIW--GYTCTCSPGYEGSNCELAKNECHPERTDGCQHFCLPGQESY 148 Query: 401 KCACPVTY 424 C+C Y Sbjct: 149 TCSCAQGY 156 Score = 29.9 bits (64), Expect = 5.9 Identities = 10/25 (40%), Positives = 13/25 (52%) Frame = +2 Query: 371 GKCMNTADSYKCACPVTYTGKNCEV 445 G C ++ Y C C Y G NCE+ Sbjct: 100 GSCQDSIWGYTCTCSPGYEGSNCEL 124 >X87241-1|CAA60685.1| 4590|Homo sapiens homologue of Drosophila Fat protein protein. Length = 4590 Score = 55.2 bits (127), Expect = 1e-07 Identities = 28/73 (38%), Positives = 33/73 (45%), Gaps = 1/73 (1%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLCGPGK-CMNTADSYK 403 C C N G C ++L G VC C GF G C + C C G C NT SY Sbjct: 4095 CKDEPCKNGGTCFDSLD--GAVCQCDSGFRGERCQSDIDECSGNPCLHGALCENTHGSYH 4152 Query: 404 CACPVTYTGKNCE 442 C C Y G++CE Sbjct: 4153 CNCSHEYRGRHCE 4165 Score = 51.6 bits (118), Expect = 2e-06 Identities = 35/120 (29%), Positives = 53/120 (44%), Gaps = 13/120 (10%) Frame = +2 Query: 125 SGFVGCISMLILGNEEKNI----MALALEKENVQ---NCFT-----CAPNLCLNNGVCQE 268 +GF GC+ + L +E + + A +E+V CF CA N C N GVC Sbjct: 3973 NGFRGCMDSIYLNGQELPLNSKPRSYAHIEESVDVSPGCFLTATEDCASNPCQNGGVCNP 4032 Query: 269 ALTEHGYVCLCAPGFGGNNCDRIGESCRPGLC-GPGKCMNTADSYKCACPVTYTGKNCEV 445 + GY C C+ + G +C+ C C G C+ + C C YTG+ C++ Sbjct: 4033 S-PAGGYYCKCSALYIGTHCEISVNPCSSNPCLYGGTCVVDNGGFVCQCRGLYTGQRCQL 4091 >AB208840-1|BAD92077.1| 830|Homo sapiens fibrillin 1 variant protein. Length = 830 Score = 55.2 bits (127), Expect = 1e-07 Identities = 32/87 (36%), Positives = 39/87 (44%), Gaps = 8/87 (9%) Frame = +2 Query: 203 ENVQNCFTCAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNN----CDRIGESCRPGLCGP 370 E++ C P LC G C T + C C G+ N CD + E PG+CGP Sbjct: 40 EDIDECQEL-PGLC-QGGKCIN--TFGSFQCRCPTGYYLNEDTRVCDDVNECETPGICGP 95 Query: 371 GKCMNTADSYKCACPVTYT----GKNC 439 G C NT +Y C CP Y G NC Sbjct: 96 GTCYNTVGNYTCICPPDYMQVNGGNNC 122 Score = 50.0 bits (114), Expect = 5e-06 Identities = 33/95 (34%), Positives = 43/95 (45%), Gaps = 8/95 (8%) Frame = +2 Query: 206 NVQNCFTCAPNLCLNNGVCQEALTEHGYVCLCAPGF----GGNNCDRIGESC-RPGLCGP 370 +V C + NLC NG C T + C C G+ G C I E P C P Sbjct: 365 DVDECASGNGNLC-RNGQCIN--TVGSFQCQCNEGYEVAPDGRTCVDINECLLEPRKCAP 421 Query: 371 GKCMNTADSYKCACPVTYTGKN--CE-VKQLIEYP 466 G C N SY+C CP Y+ +N CE + + +E P Sbjct: 422 GTCQNLDGSYRCICPPGYSLQNEKCEDIDECVEEP 456 Score = 49.6 bits (113), Expect = 7e-06 Identities = 28/83 (33%), Positives = 41/83 (49%), Gaps = 8/83 (9%) Frame = +2 Query: 254 GVCQEALTEHGYVCLCAPGFGGNN--CDRIGESCR-PGLCGPGKCMNTADSYKCACP--- 415 G CQ + Y C+C PG+ N C+ I E P +C G C NT S+KC CP Sbjct: 422 GTCQNL--DGSYRCICPPGYSLQNEKCEDIDECVEEPEICALGTCSNTEGSFKCLCPEGF 479 Query: 416 -VTYTGKNC-EVKQLIEYPAFTG 478 ++ +G+ C +++ Y F G Sbjct: 480 SLSSSGRRCQDLRMSYCYAKFEG 502 Score = 46.0 bits (104), Expect = 8e-05 Identities = 20/52 (38%), Positives = 28/52 (53%), Gaps = 5/52 (9%) Frame = +2 Query: 287 YVCLCAPGF----GGNNCDRIGE-SCRPGLCGPGKCMNTADSYKCACPVTYT 427 Y+C+C PG+ G C E +PG+C G+C+NT SY C C +T Sbjct: 707 YMCICGPGYQRRPDGEGCVDENECQTKPGICENGRCLNTRGSYTCECNDGFT 758 Score = 44.4 bits (100), Expect = 3e-04 Identities = 24/66 (36%), Positives = 32/66 (48%), Gaps = 3/66 (4%) Frame = +2 Query: 236 NLCLNNGVCQEALTEHGYVCLCAPGFGGN---NCDRIGESCRPGLCGPGKCMNTADSYKC 406 N C NG C+ + G+ C C GF C+ I E + L +C+NT SY+C Sbjct: 609 NPC-GNGTCKNVIG--GFECTCEEGFEPGPMMTCEDINECAQNPLLCAFRCVNTYGSYEC 665 Query: 407 ACPVTY 424 CPV Y Sbjct: 666 KCPVGY 671 Score = 44.0 bits (99), Expect = 3e-04 Identities = 25/64 (39%), Positives = 32/64 (50%), Gaps = 4/64 (6%) Frame = +2 Query: 233 PNLCLNNGVCQEALTEHGYVCLCAPGFGGNN----CDRIGESCRPGLCGPGKCMNTADSY 400 PN+C ++G C + T + CLC GF N+ C I E C CG G C NT S+ Sbjct: 292 PNIC-SHGQCID--TVGSFYCLCHTGFKTNDDQTMCLDINE-CERDACGNGTCRNTIGSF 347 Query: 401 KCAC 412 C C Sbjct: 348 NCRC 351 Score = 37.1 bits (82), Expect = 0.039 Identities = 15/36 (41%), Positives = 21/36 (58%), Gaps = 3/36 (8%) Frame = +2 Query: 341 ESCR-PGLCGPGKCMNTADSYKCACPVTY--TGKNC 439 + C+ P +C G+C+NT SY+C CP Y G C Sbjct: 564 DECKEPDVCKHGQCINTDGSYRCECPFGYILAGNEC 599 Score = 36.7 bits (81), Expect = 0.052 Identities = 24/69 (34%), Positives = 33/69 (47%), Gaps = 5/69 (7%) Frame = +2 Query: 233 PNLCLNNGVCQEALTEHGYVCLCAPGFGGNN----CDRIGESCRPGLCGPG-KCMNTADS 397 P +C NGVC + + C C GF N+ C+ I E +C +C+NTA S Sbjct: 209 PGVC-ENGVCINMVGS--FRCECPVGFFYNDKLLVCEDIDECQNGPVCQRNAECINTAGS 265 Query: 398 YKCACPVTY 424 Y+C C Y Sbjct: 266 YRCDCKPGY 274 Score = 36.7 bits (81), Expect = 0.052 Identities = 20/62 (32%), Positives = 27/62 (43%), Gaps = 2/62 (3%) Frame = +2 Query: 233 PNLCLNNGVCQEALTEHGYVCLCAPGF--GGNNCDRIGESCRPGLCGPGKCMNTADSYKC 406 P++C +G C T+ Y C C G+ GN C E CG G C N ++C Sbjct: 569 PDVC-KHGQCIN--TDGSYRCECPFGYILAGNECVDTDECSVGNPCGNGTCKNVIGGFEC 625 Query: 407 AC 412 C Sbjct: 626 TC 627 Score = 35.5 bits (78), Expect = 0.12 Identities = 13/30 (43%), Positives = 19/30 (63%), Gaps = 2/30 (6%) Frame = +2 Query: 341 ESCR--PGLCGPGKCMNTADSYKCACPVTY 424 + CR PG+C G C+N S++C CPV + Sbjct: 203 DECREIPGVCENGVCINMVGSFRCECPVGF 232 >BC027939-1|AAH27939.1| 600|Homo sapiens SNED1 protein protein. Length = 600 Score = 54.4 bits (125), Expect = 2e-07 Identities = 23/72 (31%), Positives = 37/72 (51%), Gaps = 1/72 (1%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLCGP-GKCMNTADSYK 403 C + C + G C+ Y+C+C F G +C+ + + C CG G C+ + S+ Sbjct: 68 CDSSPCQHGGRCESG--GGAYLCVCPESFFGYHCETVSDPCFSSPCGGRGYCLASNGSHS 125 Query: 404 CACPVTYTGKNC 439 C C V YTG++C Sbjct: 126 CTCKVGYTGEDC 137 Score = 52.4 bits (120), Expect = 1e-06 Identities = 24/73 (32%), Positives = 36/73 (49%), Gaps = 1/73 (1%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLCGPG-KCMNTADSYK 403 C + C N G C+ YVC C GF G +C+ ++C C G +C + +Y Sbjct: 30 CRAHPCRNGGSCRNL--PGAYVCRCPAGFVGVHCETEVDACDSSPCQHGGRCESGGGAYL 87 Query: 404 CACPVTYTGKNCE 442 C CP ++ G +CE Sbjct: 88 CVCPESFFGYHCE 100 Score = 35.1 bits (77), Expect = 0.16 Identities = 14/35 (40%), Positives = 16/35 (45%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCD 331 C+ N C N G C H C C PGF G C+ Sbjct: 513 CSENPCQNGGTCVPGADAHS--CDCGPGFKGRRCE 545 Score = 33.9 bits (74), Expect = 0.36 Identities = 13/37 (35%), Positives = 18/37 (48%), Gaps = 1/37 (2%) Frame = +2 Query: 341 ESCRPGLC-GPGKCMNTADSYKCACPVTYTGKNCEVK 448 + CR C G C N +Y C CP + G +CE + Sbjct: 28 DECRAHPCRNGGSCRNLPGAYVCRCPAGFVGVHCETE 64 >AK074075-1|BAB84901.1| 522|Homo sapiens FLJ00146 protein protein. Length = 522 Score = 54.4 bits (125), Expect = 2e-07 Identities = 23/72 (31%), Positives = 37/72 (51%), Gaps = 1/72 (1%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLCGP-GKCMNTADSYK 403 C + C + G C+ Y+C+C F G +C+ + + C CG G C+ + S+ Sbjct: 3 CDSSPCQHGGRCESG--GGAYLCVCPESFFGYHCETVSDPCFSSPCGGRGYCLASNGSHS 60 Query: 404 CACPVTYTGKNC 439 C C V YTG++C Sbjct: 61 CTCKVGYTGEDC 72 Score = 35.1 bits (77), Expect = 0.16 Identities = 14/35 (40%), Positives = 16/35 (45%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCD 331 C+ N C N G C H C C PGF G C+ Sbjct: 448 CSENPCQNGGTCVPGADAHS--CDCGPGFKGRRCE 480 Score = 29.5 bits (63), Expect = 7.8 Identities = 9/24 (37%), Positives = 15/24 (62%) Frame = +2 Query: 371 GKCMNTADSYKCACPVTYTGKNCE 442 G+C + +Y C CP ++ G +CE Sbjct: 12 GRCESGGGAYLCVCPESFFGYHCE 35 >U03272-1|AAA18950.1| 2911|Homo sapiens fibrillin-2 protein. Length = 2911 Score = 53.6 bits (123), Expect = 4e-07 Identities = 26/65 (40%), Positives = 37/65 (56%), Gaps = 5/65 (7%) Frame = +2 Query: 236 NLCLNNGVCQEALTEHG-YVCLCAPGF----GGNNCDRIGESCRPGLCGPGKCMNTADSY 400 N+CLN G+C + E G + C+C PGF G C + E PG+C G C+N+ S+ Sbjct: 624 NMCLN-GMC---INEDGSFKCICKPGFVLAPNGRYCTDVDECQTPGICMNGHCINSEGSF 679 Query: 401 KCACP 415 +C CP Sbjct: 680 RCDCP 684 Score = 49.2 bits (112), Expect = 9e-06 Identities = 33/103 (32%), Positives = 47/103 (45%), Gaps = 10/103 (9%) Frame = +2 Query: 203 ENVQNCFTCAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGES-----CRPGLCG 367 E++ C P LC G C T + C C G+ + RI E PG+CG Sbjct: 1648 EDIDECQEL-PGLC-QGGNCIN--TFGSFQCECPQGYYLSEDTRICEDIDECFAHPGVCG 1703 Query: 368 PGKCMNTADSYKCACPVTYT----GKNC-EVKQLIEYPAFTGS 481 PG C NT +Y C CP Y G NC ++++ Y ++ G+ Sbjct: 1704 PGTCYNTLGNYTCICPPEYMQVNGGHNCMDMRKSFCYRSYNGT 1746 Score = 47.2 bits (107), Expect = 4e-05 Identities = 30/95 (31%), Positives = 42/95 (44%), Gaps = 8/95 (8%) Frame = +2 Query: 206 NVQNCFTCAPNLCLNNGVCQEALTEHGYVCLCAPGF----GGNNCDRIGESCR-PGLCGP 370 ++ C + +C NG C + + CLC G+ G NC E PG C P Sbjct: 1972 DIDECSSFFGQVC-RNGRCFNEIGS--FKCLCNEGYELTPDGKNCIDTNECVALPGSCSP 2028 Query: 371 GKCMNTADSYKCACPVTYTGK--NC-EVKQLIEYP 466 G C N S++C CP Y K NC ++ + E P Sbjct: 2029 GTCQNLEGSFRCICPPGYEVKSENCIDINECDEDP 2063 Score = 47.2 bits (107), Expect = 4e-05 Identities = 28/74 (37%), Positives = 32/74 (43%), Gaps = 4/74 (5%) Frame = +2 Query: 206 NVQNCFTCAPNLCLNNGVCQEALTEHGYVCLCAPGF----GGNNCDRIGESCRPGLCGPG 373 N ++ C N +G CQ L GY C C G+ N C E P CG Sbjct: 2610 NCEDVDECDGNHRCQHG-CQNILG--GYRCGCPQGYIQHYQWNQCVDENECSNPNACGSA 2666 Query: 374 KCMNTADSYKCACP 415 C NT SYKCACP Sbjct: 2667 SCYNTLGSYKCACP 2680 Score = 45.6 bits (103), Expect = 1e-04 Identities = 27/86 (31%), Positives = 38/86 (44%), Gaps = 5/86 (5%) Frame = +2 Query: 182 MALALEKENVQNCFTCAPNLCLNNGVCQEALTEHGYVCLCAPGF----GGNNCDRIGESC 349 + + ++ ++ C P++C N G+C+ Y C C G+ G NC I E Sbjct: 759 VGITVDGRDINEC-ALDPDICAN-GICENL--RGSYRCNCNSGYEPDASGRNCIDIDECL 814 Query: 350 -RPGLCGPGKCMNTADSYKCACPVTY 424 LC G C NT SY C CP Y Sbjct: 815 VNRLLCDNGLCRNTPGSYSCTCPPGY 840 Score = 45.6 bits (103), Expect = 1e-04 Identities = 31/80 (38%), Positives = 38/80 (47%), Gaps = 9/80 (11%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGF---GGNNCDRIGE--SCRPGLCGPGKCMNTA 391 C + C NG C+ T Y CLC PGF N+C I E S +C G+C N Sbjct: 1937 CERHPC-GNGTCKN--TVGSYNCLCYPGFELTHNNDCLDIDECSSFFGQVCRNGRCFNEI 1993 Query: 392 DSYKCAC----PVTYTGKNC 439 S+KC C +T GKNC Sbjct: 1994 GSFKCLCNEGYELTPDGKNC 2013 Score = 44.0 bits (99), Expect = 3e-04 Identities = 29/86 (33%), Positives = 42/86 (48%), Gaps = 8/86 (9%) Frame = +2 Query: 185 ALALEKENVQNCFTC--APNLCLNNGVCQEALTEHGYVCLCAPGFGGN-----NC-DRIG 340 AL +E+ N + C +P+LC +G+C T + C C G+ NC D G Sbjct: 1104 ALDMEERNCTDIDECRISPDLC-GSGICVN--TPGSFECECFEGYESGFMMMKNCMDIDG 1160 Query: 341 ESCRPGLCGPGKCMNTADSYKCACPV 418 P LC G C+NT S++C CP+ Sbjct: 1161 CERNPLLCRGGTCVNTEGSFQCDCPL 1186 Score = 43.6 bits (98), Expect = 4e-04 Identities = 24/66 (36%), Positives = 31/66 (46%), Gaps = 3/66 (4%) Frame = +2 Query: 236 NLCLNNGVCQEALTEHGYVCLCAPGFGGN---NCDRIGESCRPGLCGPGKCMNTADSYKC 406 N C NG C + + C C GF NC+ I E + L +CMNT SY+C Sbjct: 2220 NPC-GNGTCTNVIGS--FECNCNEGFEPGPMMNCEDINECAQNPLLCALRCMNTFGSYEC 2276 Query: 407 ACPVTY 424 CP+ Y Sbjct: 2277 TCPIGY 2282 Score = 43.2 bits (97), Expect = 6e-04 Identities = 23/64 (35%), Positives = 32/64 (50%), Gaps = 4/64 (6%) Frame = +2 Query: 233 PNLCLNNGVCQEALTEHGYVCLCAPGFGGNN----CDRIGESCRPGLCGPGKCMNTADSY 400 PN+C ++G+C + + Y C+C GF + C + E C CG G C NT SY Sbjct: 1899 PNVC-SHGLCVDL--QGSYQCICHNGFKASQDQTMCMDVDE-CERHPCGNGTCKNTVGSY 1954 Query: 401 KCAC 412 C C Sbjct: 1955 NCLC 1958 Score = 42.7 bits (96), Expect = 8e-04 Identities = 23/64 (35%), Positives = 30/64 (46%), Gaps = 3/64 (4%) Frame = +2 Query: 233 PNLCLNNGVCQEALTEHGYVCLCAPGFG--GNNCDRIGESCR-PGLCGPGKCMNTADSYK 403 P C + G CQ E + C+C PG+ NC I E P +C G C NT ++ Sbjct: 2023 PGSC-SPGTCQNL--EGSFRCICPPGYEVKSENCIDINECDEDPNICLFGSCTNTPGGFQ 2079 Query: 404 CACP 415 C CP Sbjct: 2080 CLCP 2083 Score = 42.3 bits (95), Expect = 0.001 Identities = 27/85 (31%), Positives = 43/85 (50%), Gaps = 9/85 (10%) Frame = +2 Query: 185 ALALEKENVQNCFTCAPNL--CLNNGV-CQEALTEHGYVCLCAPGFG----GNNCDRIGE 343 AL +++ ++ CA L C + G+ C+ + ++C+C PG G C E Sbjct: 2283 ALREDQKMCKDLDECAEGLHDCESRGMMCKNLIGT--FMCICPPGMARRPDGEGCVDENE 2340 Query: 344 SCR--PGLCGPGKCMNTADSYKCAC 412 CR PG+C G+C+N SY+C C Sbjct: 2341 -CRTKPGICENGRCVNIIGSYRCEC 2364 Score = 42.3 bits (95), Expect = 0.001 Identities = 24/68 (35%), Positives = 29/68 (42%), Gaps = 4/68 (5%) Frame = +2 Query: 233 PNLCLNNGVCQEALTEHGYVCLCAPGFG----GNNCDRIGESCRPGLCGPGKCMNTADSY 400 P LC G+CQ T + C C GF G NC+ + E C G C N Y Sbjct: 2578 PLLCGGKGICQN--TPGSFSCECQRGFSLDATGLNCEDVDECDGNHRCQHG-CQNILGGY 2634 Query: 401 KCACPVTY 424 +C CP Y Sbjct: 2635 RCGCPQGY 2642 Score = 41.9 bits (94), Expect = 0.001 Identities = 27/79 (34%), Positives = 35/79 (44%), Gaps = 5/79 (6%) Frame = +2 Query: 203 ENVQNCFTCAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNN----CDRIGE-SCRPGLCG 367 ++V C P +C G C T + C C G + C+ I E S PG+C Sbjct: 274 QDVDEC-QAIPGIC-QGGNCIN--TVGSFECRCPAGHKQSETTQKCEDIDECSIIPGICE 329 Query: 368 PGKCMNTADSYKCACPVTY 424 G+C NT SY C CP Y Sbjct: 330 TGECSNTVGSYFCVCPRGY 348 Score = 41.9 bits (94), Expect = 0.001 Identities = 25/66 (37%), Positives = 32/66 (48%), Gaps = 6/66 (9%) Frame = +2 Query: 233 PNLCLNNGVCQEALTEHGYVCLCAPGFG----GNNCDRIGESCR--PGLCGPGKCMNTAD 394 P +C G C+ + + C C GF NC I E CR P LCG G C+NT Sbjct: 1080 PGMC-TYGKCRNTIGS--FKCRCNSGFALDMEERNCTDIDE-CRISPDLCGSGICVNTPG 1135 Query: 395 SYKCAC 412 S++C C Sbjct: 1136 SFECEC 1141 Score = 41.9 bits (94), Expect = 0.001 Identities = 28/92 (30%), Positives = 41/92 (44%), Gaps = 9/92 (9%) Frame = +2 Query: 191 ALEKENVQNCFTCA-PNLCLNNGVCQEALTEHGYVCLCAPGFG----GNNCDRIGESCRP 355 A + + Q+ C+ N+C++ G C + C+C G+ G NC I E P Sbjct: 1482 ASDSRSCQDIDECSFQNICVS-GTCNNL--PGMFHCICDDGYELDRTGGNCTDIDECADP 1538 Query: 356 GLCGPGKCMNTADSYKCACPVTY----TGKNC 439 C G C+NT Y+C CP + TG C Sbjct: 1539 INCVNGLCVNTPGRYECNCPPDFQLNPTGVGC 1570 Score = 41.5 bits (93), Expect = 0.002 Identities = 21/65 (32%), Positives = 30/65 (46%), Gaps = 3/65 (4%) Frame = +2 Query: 242 CLNNGVCQEALTEHGYVCLCAPGFGGNN--CDRIGESCRP-GLCGPGKCMNTADSYKCAC 412 C N C T Y C C+ GF G+ C + E LC G+C+N +Y+C C Sbjct: 1418 CSINAQCVN--TPGSYRCACSEGFTGDGFTCSDVDECAENINLCENGQCLNVPGAYRCEC 1475 Query: 413 PVTYT 427 + +T Sbjct: 1476 EMGFT 1480 Score = 39.9 bits (89), Expect = 0.006 Identities = 23/67 (34%), Positives = 29/67 (43%), Gaps = 5/67 (7%) Frame = +2 Query: 227 CAPN-LCLNNGVCQEALTEHGYVCLCAPGF----GGNNCDRIGESCRPGLCGPGKCMNTA 391 C N L +NG+C+ T Y C C PG+ C+ I E C C G C N Sbjct: 813 CLVNRLLCDNGLCRN--TPGSYSCTCPPGYVFRTETETCEDINE-CESNPCVNGACRNNL 869 Query: 392 DSYKCAC 412 S+ C C Sbjct: 870 GSFNCEC 876 Score = 39.9 bits (89), Expect = 0.006 Identities = 19/49 (38%), Positives = 26/49 (53%), Gaps = 2/49 (4%) Frame = +2 Query: 287 YVCLCAPGFGGNNCDRIGESCR--PGLCGPGKCMNTADSYKCACPVTYT 427 Y +C G G R + C+ P LC G+C+NT S++C C V YT Sbjct: 2432 YKKICPHGPGYTTDGRDIDECKVMPNLCTNGQCINTMGSFRCFCKVGYT 2480 Score = 39.9 bits (89), Expect = 0.006 Identities = 24/61 (39%), Positives = 31/61 (50%), Gaps = 8/61 (13%) Frame = +2 Query: 284 GYVCLCAPGFGGNNCDRIGES-C--RPGLCG-PGKCMNTADSYKCAC----PVTYTGKNC 439 G+ C C PGF ++ I + C +P LCG G C NT S+ C C + TG NC Sbjct: 2552 GFTCKCPPGFTQHHTACIDNNECGSQPLLCGGKGICQNTPGSFSCECQRGFSLDATGLNC 2611 Query: 440 E 442 E Sbjct: 2612 E 2612 Score = 39.5 bits (88), Expect = 0.007 Identities = 29/86 (33%), Positives = 39/86 (45%), Gaps = 2/86 (2%) Frame = +2 Query: 161 GNEEKNIMALALEKENVQNCFTCAPNLCLNNGVCQEALTEHGYVCLCAPGFGGN-NCDRI 337 G + I L + + + C A NLCLN G C ++ Y C C G+ + N D I Sbjct: 478 GGQGPIITGLTILNQTIDICKHHA-NLCLN-GRCIPTVSS--YRCECNMGYKQDANGDCI 533 Query: 338 G-ESCRPGLCGPGKCMNTADSYKCAC 412 + C C G C+NT SY C C Sbjct: 534 DVDECTSNPCTNGDCVNTPGSYYCKC 559 Score = 39.5 bits (88), Expect = 0.007 Identities = 24/74 (32%), Positives = 31/74 (41%), Gaps = 7/74 (9%) Frame = +2 Query: 212 QNCFTCAPNLCLNNGVCQEALT--EHGYVCLCAPGFG----GNNCDRIGE-SCRPGLCGP 370 Q C T + NG C T E Y C C+ G+ G +C I E P +C Sbjct: 1237 QGC-TDIDECMIMNGGCDTQCTNSEGSYECSCSEGYALMPDGRSCADIDECENNPDICDG 1295 Query: 371 GKCMNTADSYKCAC 412 G+C N Y+C C Sbjct: 1296 GQCTNIPGEYRCLC 1309 Score = 39.5 bits (88), Expect = 0.007 Identities = 15/33 (45%), Positives = 21/33 (63%), Gaps = 4/33 (12%) Frame = +2 Query: 353 PGLCGPGKCMNTADSYKCACP----VTYTGKNC 439 PG+C G+C+NT S++C CP + YTG C Sbjct: 2178 PGICSNGQCINTDGSFRCECPMGYNLDYTGVRC 2210 Score = 39.1 bits (87), Expect = 0.010 Identities = 29/79 (36%), Positives = 36/79 (45%), Gaps = 9/79 (11%) Frame = +2 Query: 233 PNLCLNNGVCQEALTEHGYVCLCAPGF----GGNNCDRIGE-SCRPGLCGPGKCMNTADS 397 PNLC NG C T + C C G+ G +C + E S P C C NT S Sbjct: 2456 PNLC-TNGQCIN--TMGSFRCFCKVGYTTDISGTSCIDLDECSQSPKPCNY-ICKNTEGS 2511 Query: 398 YKCACPVTYT----GKNCE 442 Y+C+CP Y GK C+ Sbjct: 2512 YQCSCPRGYVLQEDGKTCK 2530 Score = 38.7 bits (86), Expect = 0.013 Identities = 21/65 (32%), Positives = 30/65 (46%), Gaps = 8/65 (12%) Frame = +2 Query: 242 CLNNGV-CQEAL---TEHGYVCLCAPGF----GGNNCDRIGESCRPGLCGPGKCMNTADS 397 C+ NGV C+ ++ + C+C GF G NC E +C G C+N S Sbjct: 578 CIQNGVLCKNGRCVNSDGSFQCICNAGFELTTDGKNCVDHDECTTTNMCLNGMCINEDGS 637 Query: 398 YKCAC 412 +KC C Sbjct: 638 FKCIC 642 Score = 37.9 bits (84), Expect = 0.022 Identities = 23/75 (30%), Positives = 33/75 (44%), Gaps = 4/75 (5%) Frame = +2 Query: 200 KENVQNCFTCAPNLCLNNGVCQEALTEHGYVCLCAPGFG----GNNCDRIGESCRPGLCG 367 +E+V C +P +C +NG C T+ + C C G+ G C E CG Sbjct: 2168 REDVNECLE-SPGIC-SNGQCIN--TDGSFRCECPMGYNLDYTGVRCVDTDECSIGNPCG 2223 Query: 368 PGKCMNTADSYKCAC 412 G C N S++C C Sbjct: 2224 NGTCTNVIGSFECNC 2238 Score = 36.7 bits (81), Expect = 0.052 Identities = 24/78 (30%), Positives = 34/78 (43%) Frame = +2 Query: 242 CLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLCGPGKCMNTADSYKCACPVT 421 C+N G C + +H C C G+ G C + C G G+C+ + CAC Sbjct: 153 CMNGGTCAD---DH---CQCQKGYIGTYCGQ--PVCENGCQNGGRCI----AQPCACVYG 200 Query: 422 YTGKNCEVKQLIEYPAFT 475 +TG CE + P FT Sbjct: 201 FTGPQCE-RDYRTGPCFT 217 Score = 35.9 bits (79), Expect = 0.090 Identities = 26/80 (32%), Positives = 30/80 (37%), Gaps = 9/80 (11%) Frame = +2 Query: 227 CAPNLCL-NNGVCQEALTEHGYVCLCAPGF----GGNNCDRIGESCRPGLCGPGKCMNTA 391 CA N+ L NG C Y C C GF +C I E +C G C N Sbjct: 1452 CAENINLCENGQCLNV--PGAYRCECEMGFTPASDSRSCQDIDECSFQNICVSGTCNNLP 1509 Query: 392 DSYKCACPVTY----TGKNC 439 + C C Y TG NC Sbjct: 1510 GMFHCICDDGYELDRTGGNC 1529 Score = 35.1 bits (77), Expect = 0.16 Identities = 14/35 (40%), Positives = 21/35 (60%), Gaps = 2/35 (5%) Frame = +2 Query: 317 GNNCDRIGESCR--PGLCGPGKCMNTADSYKCACP 415 G C+ + E C PG+C G+C+N+ S+ C CP Sbjct: 949 GVTCEDVNE-CEVFPGVCPNGRCVNSKGSFHCECP 982 Score = 35.1 bits (77), Expect = 0.16 Identities = 24/69 (34%), Positives = 30/69 (43%), Gaps = 5/69 (7%) Frame = +2 Query: 233 PNLCLNNGVCQEALTEHGYVCLCAPGF----GGNNCDRIGE-SCRPGLCGPGKCMNTADS 397 P LC G C TE + C C G +C I E S LC GKC+N + Sbjct: 1165 PLLC-RGGTCVN--TEGSFQCDCPLGHELSPSREDCVDINECSLSDNLCRNGKCVNMIGT 1221 Query: 398 YKCACPVTY 424 Y+C+C Y Sbjct: 1222 YQCSCNPGY 1230 Score = 35.1 bits (77), Expect = 0.16 Identities = 23/72 (31%), Positives = 33/72 (45%), Gaps = 5/72 (6%) Frame = +2 Query: 233 PNLCLNNGVCQEALTEHGYVCLCAPGFGGN----NCDRIGE-SCRPGLCGPGKCMNTADS 397 P++C + G C E Y CLC GF + C + E +C G+C NT S Sbjct: 1290 PDIC-DGGQCTNIPGE--YRCLCYDGFMASMDMKTCIDVNECDLNSNICMFGECENTKGS 1346 Query: 398 YKCACPVTYTGK 433 + C C + Y+ K Sbjct: 1347 FICHCQLGYSVK 1358 Score = 35.1 bits (77), Expect = 0.16 Identities = 19/52 (36%), Positives = 26/52 (50%), Gaps = 4/52 (7%) Frame = +2 Query: 287 YVCLCAPGFGGNNCDRIG-ESCRPGL--CG-PGKCMNTADSYKCACPVTYTG 430 + C C G+ GN I + C G C +C+NT SY+CAC +TG Sbjct: 1390 FKCSCREGWIGNGIKCIDLDECSNGTHQCSINAQCVNTPGSYRCACSEGFTG 1441 Score = 34.3 bits (75), Expect = 0.27 Identities = 30/83 (36%), Positives = 34/83 (40%), Gaps = 12/83 (14%) Frame = +2 Query: 233 PNLCLNNGVCQEALTEHGYVCLCAPGF----GGNNC-DRIGESC----RPGLCGPGKCMN 385 PN+CL G C T G+ CLC PGF G C D C G C K N Sbjct: 2063 PNICLF-GSCTN--TPGGFQCLCPPGFVLSDNGRRCFDTRQSFCFTNFENGKCSVPKAFN 2119 Query: 386 TADSYKCAC---PVTYTGKNCEV 445 T + KC C P G CE+ Sbjct: 2120 TTKA-KCCCSKMPGEGWGDPCEL 2141 Score = 33.9 bits (74), Expect = 0.36 Identities = 10/25 (40%), Positives = 16/25 (64%) Frame = +2 Query: 353 PGLCGPGKCMNTADSYKCACPVTYT 427 PG+C G C+N S++C CP ++ Sbjct: 1815 PGICANGVCINQIGSFRCECPTGFS 1839 Score = 33.9 bits (74), Expect = 0.36 Identities = 24/71 (33%), Positives = 26/71 (36%), Gaps = 8/71 (11%) Frame = +2 Query: 236 NLCLNNGVCQEAL---TEHGYVCLCAPGFG----GNNCDRIGE-SCRPGLCGPGKCMNTA 391 N C N C A T Y C C GF + C + E S C G C NT Sbjct: 2655 NECSNPNACGSASCYNTLGSYKCACPSGFSFDQFSSACHDVNECSSSKNPCNYG-CSNTE 2713 Query: 392 DSYKCACPVTY 424 Y C CP Y Sbjct: 2714 GGYLCGCPPGY 2724 Score = 33.5 bits (73), Expect = 0.48 Identities = 24/67 (35%), Positives = 32/67 (47%), Gaps = 7/67 (10%) Frame = +2 Query: 233 PNLCLNNGVCQEALTEHGYVCLCAPGFGGNN----CDRIGESCRPG--LCGPGK-CMNTA 391 P +C N GVC + + C C GF N+ C+ I E C G LC C+N+ Sbjct: 1815 PGICAN-GVCINQIGS--FRCECPTGFSYNDLLLVCEDIDE-CSNGDNLCQRNADCINSP 1870 Query: 392 DSYKCAC 412 SY+C C Sbjct: 1871 GSYRCEC 1877 Score = 33.1 bits (72), Expect = 0.63 Identities = 26/87 (29%), Positives = 38/87 (43%), Gaps = 9/87 (10%) Frame = +2 Query: 206 NVQNCFTCAPNLCLNNGVCQEALTEHGYVCLCAPGFGGN----NCDRIGESC-RPGLCGP 370 ++ C + + NLC NG C + Y C C PG+ C I E G C Sbjct: 1199 DINEC-SLSDNLC-RNGKCVNMIGT--YQCSCNPGYQATPDRQGCTDIDECMIMNGGCDT 1254 Query: 371 GKCMNTADSYKCACPVTYT----GKNC 439 +C N+ SY+C+C Y G++C Sbjct: 1255 -QCTNSEGSYECSCSEGYALMPDGRSC 1280 Score = 31.1 bits (67), Expect = 2.6 Identities = 23/82 (28%), Positives = 36/82 (43%), Gaps = 7/82 (8%) Frame = +2 Query: 236 NLCLNNGVCQEALTEHGYVCLCAPGF----GGNNCDRIGESCRPGL--CGP-GKCMNTAD 394 N+C+ G C+ T+ ++C C G+ G C + E C G C C+N Sbjct: 1333 NICMF-GECEN--TKGSFICHCQLGYSVKKGTTGCTDVDE-CEIGAHNCDMHASCLNIPG 1388 Query: 395 SYKCACPVTYTGKNCEVKQLIE 460 S+KC+C + G + L E Sbjct: 1389 SFKCSCREGWIGNGIKCIDLDE 1410 Score = 30.3 bits (65), Expect = 4.5 Identities = 20/70 (28%), Positives = 28/70 (40%), Gaps = 4/70 (5%) Frame = +2 Query: 230 APNLCLNNGVCQEALTEHGYVCLCAPGF----GGNNCDRIGESCRPGLCGPGKCMNTADS 397 +P C N +C+ TE Y C C G+ G C + E C+NT Sbjct: 2497 SPKPC--NYICKN--TEGSYQCSCPRGYVLQEDGKTCKDLDECQTKQHNCQFLCVNTLGG 2552 Query: 398 YKCACPVTYT 427 + C CP +T Sbjct: 2553 FTCKCPPGFT 2562 >D87469-1|BAA13407.2| 2854|Homo sapiens KIAA0279 protein protein. Length = 2854 Score = 53.6 bits (123), Expect = 4e-07 Identities = 23/55 (41%), Positives = 30/55 (54%), Gaps = 1/55 (1%) Frame = +2 Query: 284 GYVCLCAPGFGGNNCDRIGESCRPGLCGP-GKCMNTADSYKCACPVTYTGKNCEV 445 G C C PGF G+ C+ + C CGP G+C + Y C C YTG++CEV Sbjct: 1202 GLRCRCPPGFTGDYCETEVDLCYSRPCGPHGRCRSREGGYTCLCRDGYTGEHCEV 1256 Score = 48.4 bits (110), Expect = 2e-05 Identities = 25/67 (37%), Positives = 33/67 (49%), Gaps = 4/67 (5%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGES--CRPGLC-GPGKCMN-TAD 394 C C +G C+ E GY CLC G+ G +C+ S C PG+C G C+N Sbjct: 1223 CYSRPCGPHGRCRSR--EGGYTCLCRDGYTGEHCEVSARSGRCTPGVCKNGGTCVNLLVG 1280 Query: 395 SYKCACP 415 +KC CP Sbjct: 1281 GFKCDCP 1287 Score = 46.8 bits (106), Expect = 5e-05 Identities = 30/98 (30%), Positives = 42/98 (42%), Gaps = 5/98 (5%) Frame = +2 Query: 50 LELNQPLYIGGVPDF-DQLPIDLAGASGFVGCISMLILGNEEKNIMALALEKENVQNC-- 220 L+L PL +GGVPD + P+ + FVGC+ L + + ++ V C Sbjct: 1448 LDLTGPLLLGGVPDLPESFPVRM---RQFVGCMRNLQVDSRHIDMADFIANNGTVPGCPA 1504 Query: 221 --FTCAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNC 328 C N C N G C + C C GFGG +C Sbjct: 1505 KKNVCDSNTCHNGGTCVNQW--DAFSCECPLGFGGKSC 1540 Score = 44.0 bits (99), Expect = 3e-04 Identities = 34/119 (28%), Positives = 49/119 (41%), Gaps = 10/119 (8%) Frame = +2 Query: 122 ASGFVGCISMLILGNEEKNIMALAL---EKENV-QNCFT---CAPNLCLNNGVCQEALTE 280 A GF GC+ + + + + + +L E NV Q C C N C N C Sbjct: 1686 ARGFRGCLQGVRVSDTPEGVNSLDPSHGESINVEQGCSLPDPCDSNPCPANSYCSNDWDS 1745 Query: 281 HGYVCLCAPGFGGNNCDRIGE--SC-RPGLCGPGKCMNTADSYKCACPVTYTGKNCEVK 448 Y C C PG+ G+NC + + C +C + + Y C CP Y G CE + Sbjct: 1746 --YSCSCDPGYYGDNCTNVCDLNPCEHQSVC--TRKPSAPHGYTCECPPNYLGPYCETR 1800 Score = 35.5 bits (78), Expect = 0.12 Identities = 19/58 (32%), Positives = 31/58 (53%) Frame = +2 Query: 320 NNCDRIGESCRPGLCGPGKCMNTADSYKCACPVTYTGKNCEVKQLIEYPAFTGSA*LA 493 N CD +C G G C+N D++ C CP+ + GK+C +++ F GS+ +A Sbjct: 1507 NVCD--SNTCHNG----GTCVNQWDAFSCECPLGFGGKSC-AQEMANPQHFLGSSLVA 1557 >AY356402-1|AAR13653.1| 3222|Homo sapiens fat-like cadherin FATJ protein protein. Length = 3222 Score = 53.6 bits (123), Expect = 4e-07 Identities = 27/77 (35%), Positives = 35/77 (45%), Gaps = 4/77 (5%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLCGPGK-CMNTADSYK 403 C P+ C + G C + G+ C C GF G C+R C C G C N S+ Sbjct: 2164 CLPSPCHSGGTCHNLVG--GFSCSCPDGFTGRACERDINECLQSPCKNGAICQNFPGSFN 2221 Query: 404 CACPVTYT---GKNCEV 445 C C YT GK+CE+ Sbjct: 2222 CVCKTGYTGVFGKHCEL 2238 Score = 52.4 bits (120), Expect = 1e-06 Identities = 21/68 (30%), Positives = 36/68 (52%), Gaps = 3/68 (4%) Frame = +2 Query: 287 YVCLCAPGFGGNNCDRIGESCRPGLC-GPGKCMNTADSYKCACPVTYTGKNCE--VKQLI 457 ++C C PG+ G+ C+ + C P C G C N + C+CP +TG+ CE + + + Sbjct: 2144 FLCKCLPGYAGSWCEIDIDECLPSPCHSGGTCHNLVGGFSCSCPDGFTGRACERDINECL 2203 Query: 458 EYPAFTGS 481 + P G+ Sbjct: 2204 QSPCKNGA 2211 Score = 44.4 bits (100), Expect = 3e-04 Identities = 39/132 (29%), Positives = 62/132 (46%), Gaps = 8/132 (6%) Frame = +2 Query: 74 IGGVPDFDQLPIDLAGASGFVGCISMLILGNEE-----KNIMALALEKENVQNCFTC-AP 235 +GG+P +Q D A +GF GCI+ + G E K+ +A ++ K + C P Sbjct: 2586 LGGIPP-NQAHRD-AQTAGFDGCIASMWYGGESLPFSGKHSLA-SISKTDPSVKIGCRGP 2642 Query: 236 NLCLNNGVCQEALT-EHGYVCLCAP-GFGGNNCDRIGESCRPGLCGPGKCMNTADSYKCA 409 N+C +N + L Y C P G ++ + G SC PGL + C+ Sbjct: 2643 NICASNPCWGDLLCINQWYAYRCVPPGDCASHPCQNGGSCEPGL---------HSGFTCS 2693 Query: 410 CPVTYTGKNCEV 445 CP ++TG+ CE+ Sbjct: 2694 CPDSHTGRTCEM 2705 Score = 37.1 bits (82), Expect = 0.039 Identities = 23/85 (27%), Positives = 33/85 (38%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLCGPGKCMNTADSYKC 406 CA + C N G C+ L G+ C C G C+ + +C LC GK Sbjct: 2671 CASHPCQNGGSCEPGL-HSGFTCSCPDSHTGRTCEMV-VACLGVLCPQGKVCKAGSPAGH 2728 Query: 407 ACPVTYTGKNCEVKQLIEYPAFTGS 481 C ++ + + L PA GS Sbjct: 2729 VCVLSQGPEEISL-PLWAVPAIVGS 2752 >AL390252-1|CAI13170.1| 2923|Homo sapiens cadherin, EGF LAG seven-pass G-type receptor 2 (flamingo homolog, Drosophila) protein. Length = 2923 Score = 53.6 bits (123), Expect = 4e-07 Identities = 23/55 (41%), Positives = 30/55 (54%), Gaps = 1/55 (1%) Frame = +2 Query: 284 GYVCLCAPGFGGNNCDRIGESCRPGLCGP-GKCMNTADSYKCACPVTYTGKNCEV 445 G C C PGF G+ C+ + C CGP G+C + Y C C YTG++CEV Sbjct: 1271 GLRCRCPPGFTGDYCETEVDLCYSRPCGPHGRCRSREGGYTCLCRDGYTGEHCEV 1325 Score = 48.4 bits (110), Expect = 2e-05 Identities = 25/67 (37%), Positives = 33/67 (49%), Gaps = 4/67 (5%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGES--CRPGLC-GPGKCMN-TAD 394 C C +G C+ E GY CLC G+ G +C+ S C PG+C G C+N Sbjct: 1292 CYSRPCGPHGRCRSR--EGGYTCLCRDGYTGEHCEVSARSGRCTPGVCKNGGTCVNLLVG 1349 Query: 395 SYKCACP 415 +KC CP Sbjct: 1350 GFKCDCP 1356 Score = 46.8 bits (106), Expect = 5e-05 Identities = 30/98 (30%), Positives = 42/98 (42%), Gaps = 5/98 (5%) Frame = +2 Query: 50 LELNQPLYIGGVPDF-DQLPIDLAGASGFVGCISMLILGNEEKNIMALALEKENVQNC-- 220 L+L PL +GGVPD + P+ + FVGC+ L + + ++ V C Sbjct: 1517 LDLTGPLLLGGVPDLPESFPVRM---RQFVGCMRNLQVDSRHIDMADFIANNGTVPGCPA 1573 Query: 221 --FTCAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNC 328 C N C N G C + C C GFGG +C Sbjct: 1574 KKNVCDSNTCHNGGTCVNQW--DAFSCECPLGFGGKSC 1609 Score = 44.0 bits (99), Expect = 3e-04 Identities = 34/119 (28%), Positives = 49/119 (41%), Gaps = 10/119 (8%) Frame = +2 Query: 122 ASGFVGCISMLILGNEEKNIMALAL---EKENV-QNCFT---CAPNLCLNNGVCQEALTE 280 A GF GC+ + + + + + +L E NV Q C C N C N C Sbjct: 1755 ARGFRGCLQGVRVSDTPEGVNSLDPSHGESINVEQGCSLPDPCDSNPCPANSYCSNDWDS 1814 Query: 281 HGYVCLCAPGFGGNNCDRIGE--SC-RPGLCGPGKCMNTADSYKCACPVTYTGKNCEVK 448 Y C C PG+ G+NC + + C +C + + Y C CP Y G CE + Sbjct: 1815 --YSCSCDPGYYGDNCTNVCDLNPCEHQSVC--TRKPSAPHGYTCECPPNYLGPYCETR 1869 Score = 35.5 bits (78), Expect = 0.12 Identities = 19/58 (32%), Positives = 31/58 (53%) Frame = +2 Query: 320 NNCDRIGESCRPGLCGPGKCMNTADSYKCACPVTYTGKNCEVKQLIEYPAFTGSA*LA 493 N CD +C G G C+N D++ C CP+ + GK+C +++ F GS+ +A Sbjct: 1576 NVCD--SNTCHNG----GTCVNQWDAFSCECPLGFGGKSC-AQEMANPQHFLGSSLVA 1626 >AF234887-1|AAG00080.1| 2923|Homo sapiens FLAMINGO 1 protein. Length = 2923 Score = 53.6 bits (123), Expect = 4e-07 Identities = 23/55 (41%), Positives = 30/55 (54%), Gaps = 1/55 (1%) Frame = +2 Query: 284 GYVCLCAPGFGGNNCDRIGESCRPGLCGP-GKCMNTADSYKCACPVTYTGKNCEV 445 G C C PGF G+ C+ + C CGP G+C + Y C C YTG++CEV Sbjct: 1271 GLRCRCPPGFTGDYCETEVDLCYSRPCGPHGRCRSREGGYTCLCRDGYTGEHCEV 1325 Score = 48.4 bits (110), Expect = 2e-05 Identities = 25/67 (37%), Positives = 33/67 (49%), Gaps = 4/67 (5%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGES--CRPGLC-GPGKCMN-TAD 394 C C +G C+ E GY CLC G+ G +C+ S C PG+C G C+N Sbjct: 1292 CYSRPCGPHGRCRSR--EGGYTCLCRDGYTGEHCEVSARSGRCTPGVCKNGGTCVNLLVG 1349 Query: 395 SYKCACP 415 +KC CP Sbjct: 1350 GFKCDCP 1356 Score = 46.8 bits (106), Expect = 5e-05 Identities = 30/98 (30%), Positives = 42/98 (42%), Gaps = 5/98 (5%) Frame = +2 Query: 50 LELNQPLYIGGVPDF-DQLPIDLAGASGFVGCISMLILGNEEKNIMALALEKENVQNC-- 220 L+L PL +GGVPD + P+ + FVGC+ L + + ++ V C Sbjct: 1517 LDLTGPLLLGGVPDLPESFPVRM---RQFVGCMRNLQVDSRHIDMADFIANNGTVPGCPA 1573 Query: 221 --FTCAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNC 328 C N C N G C + C C GFGG +C Sbjct: 1574 KKNVCDSNTCHNGGTCVNQW--DAFSCECPLGFGGKSC 1609 Score = 44.0 bits (99), Expect = 3e-04 Identities = 34/119 (28%), Positives = 49/119 (41%), Gaps = 10/119 (8%) Frame = +2 Query: 122 ASGFVGCISMLILGNEEKNIMALAL---EKENV-QNCFT---CAPNLCLNNGVCQEALTE 280 A GF GC+ + + + + + +L E NV Q C C N C N C Sbjct: 1755 ARGFRGCLQGVRVSDTPEGVNSLDPSHGESINVEQGCSLPDPCDSNPCPANSYCSNDWDS 1814 Query: 281 HGYVCLCAPGFGGNNCDRIGE--SC-RPGLCGPGKCMNTADSYKCACPVTYTGKNCEVK 448 Y C C PG+ G+NC + + C +C + + Y C CP Y G CE + Sbjct: 1815 --YSCSCDPGYYGDNCTNVCDLNPCEHQSVC--TRKPSAPHGYTCECPPNYLGPYCETR 1869 Score = 35.5 bits (78), Expect = 0.12 Identities = 19/58 (32%), Positives = 31/58 (53%) Frame = +2 Query: 320 NNCDRIGESCRPGLCGPGKCMNTADSYKCACPVTYTGKNCEVKQLIEYPAFTGSA*LA 493 N CD +C G G C+N D++ C CP+ + GK+C +++ F GS+ +A Sbjct: 1576 NVCD--SNTCHNG----GTCVNQWDAFSCECPLGFGGKSC-AQEMANPQHFLGSSLVA 1626 >AB065955-1|BAC06168.1| 2923|Homo sapiens seven transmembrane helix receptor protein. Length = 2923 Score = 53.6 bits (123), Expect = 4e-07 Identities = 23/55 (41%), Positives = 30/55 (54%), Gaps = 1/55 (1%) Frame = +2 Query: 284 GYVCLCAPGFGGNNCDRIGESCRPGLCGP-GKCMNTADSYKCACPVTYTGKNCEV 445 G C C PGF G+ C+ + C CGP G+C + Y C C YTG++CEV Sbjct: 1271 GLRCRCPPGFTGDYCETEVDLCYSRPCGPHGRCRSREGGYTCLCRDGYTGEHCEV 1325 Score = 48.4 bits (110), Expect = 2e-05 Identities = 25/67 (37%), Positives = 33/67 (49%), Gaps = 4/67 (5%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGES--CRPGLC-GPGKCMN-TAD 394 C C +G C+ E GY CLC G+ G +C+ S C PG+C G C+N Sbjct: 1292 CYSRPCGPHGRCRSR--EGGYTCLCRDGYTGEHCEVSARSGRCTPGVCKNGGTCVNLLVG 1349 Query: 395 SYKCACP 415 +KC CP Sbjct: 1350 GFKCDCP 1356 Score = 46.8 bits (106), Expect = 5e-05 Identities = 30/98 (30%), Positives = 42/98 (42%), Gaps = 5/98 (5%) Frame = +2 Query: 50 LELNQPLYIGGVPDF-DQLPIDLAGASGFVGCISMLILGNEEKNIMALALEKENVQNC-- 220 L+L PL +GGVPD + P+ + FVGC+ L + + ++ V C Sbjct: 1517 LDLTGPLLLGGVPDLPESFPVRM---RQFVGCMRNLQVDSRHIDMADFIANNGTVPGCPA 1573 Query: 221 --FTCAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNC 328 C N C N G C + C C GFGG +C Sbjct: 1574 KKNVCDSNTCHNGGTCVNQW--DAFSCECPLGFGGKSC 1609 Score = 44.0 bits (99), Expect = 3e-04 Identities = 34/119 (28%), Positives = 49/119 (41%), Gaps = 10/119 (8%) Frame = +2 Query: 122 ASGFVGCISMLILGNEEKNIMALAL---EKENV-QNCFT---CAPNLCLNNGVCQEALTE 280 A GF GC+ + + + + + +L E NV Q C C N C N C Sbjct: 1755 ARGFRGCLQGVRVSDTPEGVNSLDPSHGESINVEQGCSLPDPCDSNPCPANSYCSNDWDS 1814 Query: 281 HGYVCLCAPGFGGNNCDRIGE--SC-RPGLCGPGKCMNTADSYKCACPVTYTGKNCEVK 448 Y C C PG+ G+NC + + C +C + + Y C CP Y G CE + Sbjct: 1815 --YSCSCDPGYYGDNCTNVCDLNPCEHQSVC--TRKPSAPHGYTCECPPNYLGPYCETR 1869 Score = 35.5 bits (78), Expect = 0.12 Identities = 19/58 (32%), Positives = 31/58 (53%) Frame = +2 Query: 320 NNCDRIGESCRPGLCGPGKCMNTADSYKCACPVTYTGKNCEVKQLIEYPAFTGSA*LA 493 N CD +C G G C+N D++ C CP+ + GK+C +++ F GS+ +A Sbjct: 1576 NVCD--SNTCHNG----GTCVNQWDAFSCECPLGFGGKSC-AQEMANPQHFLGSSLVA 1626 >AL731551-1|CAI40246.1| 3623|Homo sapiens cubilin (intrinsic factor-cobalamin receptor) protein. Length = 3623 Score = 53.2 bits (122), Expect = 6e-07 Identities = 29/84 (34%), Positives = 40/84 (47%), Gaps = 1/84 (1%) Frame = +2 Query: 209 VQNCFTCAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLC-GPGKCMN 385 VQ C + CLN G C + ++ GY C C G+ G NC C C G C++ Sbjct: 393 VQLSNICLSHPCLN-GQCIDTVS--GYFCKCDSGWTGVNCTENINECLSNPCLNGGTCVD 449 Query: 386 TADSYKCACPVTYTGKNCEVKQLI 457 DS+ C C +TG C+V Q + Sbjct: 450 GVDSFSCECTRLWTGALCQVPQQV 473 Score = 46.4 bits (105), Expect = 6e-05 Identities = 26/80 (32%), Positives = 31/80 (38%), Gaps = 6/80 (7%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCR-----PGLC-GPGKCMNT 388 C+ N C N G C + C+C P + G C C P C G C+NT Sbjct: 136 CSSNPCQNGGTCLNL--HDSFFCICPPQWKGPLCSADVNECEIYSGTPLSCQNGGTCVNT 193 Query: 389 ADSYKCACPVTYTGKNCEVK 448 SY C CP G C K Sbjct: 194 MGSYSCHCPPETYGPQCASK 213 Score = 46.0 bits (104), Expect = 8e-05 Identities = 21/70 (30%), Positives = 32/70 (45%), Gaps = 7/70 (10%) Frame = +2 Query: 290 VCLCAPGFGGNN-----CDRIGESCRPGLCGPGKCMNTADSYKCACPVTYTGKNC--EVK 448 +C C PG+ GN C ++ C C G+C++T Y C C +TG NC + Sbjct: 375 LCTCLPGYTGNGYGPNGCVQLSNICLSHPCLNGQCIDTVSGYFCKCDSGWTGVNCTENIN 434 Query: 449 QLIEYPAFTG 478 + + P G Sbjct: 435 ECLSNPCLNG 444 >AL596445-1|CAH72450.1| 3623|Homo sapiens cubilin (intrinsic factor-cobalamin receptor) protein. Length = 3623 Score = 53.2 bits (122), Expect = 6e-07 Identities = 29/84 (34%), Positives = 40/84 (47%), Gaps = 1/84 (1%) Frame = +2 Query: 209 VQNCFTCAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLC-GPGKCMN 385 VQ C + CLN G C + ++ GY C C G+ G NC C C G C++ Sbjct: 393 VQLSNICLSHPCLN-GQCIDTVS--GYFCKCDSGWTGVNCTENINECLSNPCLNGGTCVD 449 Query: 386 TADSYKCACPVTYTGKNCEVKQLI 457 DS+ C C +TG C+V Q + Sbjct: 450 GVDSFSCECTRLWTGALCQVPQQV 473 Score = 46.4 bits (105), Expect = 6e-05 Identities = 26/80 (32%), Positives = 31/80 (38%), Gaps = 6/80 (7%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCR-----PGLC-GPGKCMNT 388 C+ N C N G C + C+C P + G C C P C G C+NT Sbjct: 136 CSSNPCQNGGTCLNL--HDSFFCICPPQWKGPLCSADVNECEIYSGTPLSCQNGGTCVNT 193 Query: 389 ADSYKCACPVTYTGKNCEVK 448 SY C CP G C K Sbjct: 194 MGSYSCHCPPETYGPQCASK 213 Score = 46.0 bits (104), Expect = 8e-05 Identities = 21/70 (30%), Positives = 32/70 (45%), Gaps = 7/70 (10%) Frame = +2 Query: 290 VCLCAPGFGGNN-----CDRIGESCRPGLCGPGKCMNTADSYKCACPVTYTGKNC--EVK 448 +C C PG+ GN C ++ C C G+C++T Y C C +TG NC + Sbjct: 375 LCTCLPGYTGNGYGPNGCVQLSNICLSHPCLNGQCIDTVSGYFCKCDSGWTGVNCTENIN 434 Query: 449 QLIEYPAFTG 478 + + P G Sbjct: 435 ECLSNPCLNG 444 >AL365215-1|CAH73630.1| 3623|Homo sapiens cubilin (intrinsic factor-cobalamin receptor) protein. Length = 3623 Score = 53.2 bits (122), Expect = 6e-07 Identities = 29/84 (34%), Positives = 40/84 (47%), Gaps = 1/84 (1%) Frame = +2 Query: 209 VQNCFTCAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLC-GPGKCMN 385 VQ C + CLN G C + ++ GY C C G+ G NC C C G C++ Sbjct: 393 VQLSNICLSHPCLN-GQCIDTVS--GYFCKCDSGWTGVNCTENINECLSNPCLNGGTCVD 449 Query: 386 TADSYKCACPVTYTGKNCEVKQLI 457 DS+ C C +TG C+V Q + Sbjct: 450 GVDSFSCECTRLWTGALCQVPQQV 473 Score = 46.4 bits (105), Expect = 6e-05 Identities = 26/80 (32%), Positives = 31/80 (38%), Gaps = 6/80 (7%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCR-----PGLC-GPGKCMNT 388 C+ N C N G C + C+C P + G C C P C G C+NT Sbjct: 136 CSSNPCQNGGTCLNL--HDSFFCICPPQWKGPLCSADVNECEIYSGTPLSCQNGGTCVNT 193 Query: 389 ADSYKCACPVTYTGKNCEVK 448 SY C CP G C K Sbjct: 194 MGSYSCHCPPETYGPQCASK 213 Score = 46.0 bits (104), Expect = 8e-05 Identities = 21/70 (30%), Positives = 32/70 (45%), Gaps = 7/70 (10%) Frame = +2 Query: 290 VCLCAPGFGGNN-----CDRIGESCRPGLCGPGKCMNTADSYKCACPVTYTGKNC--EVK 448 +C C PG+ GN C ++ C C G+C++T Y C C +TG NC + Sbjct: 375 LCTCLPGYTGNGYGPNGCVQLSNICLSHPCLNGQCIDTVSGYFCKCDSGWTGVNCTENIN 434 Query: 449 QLIEYPAFTG 478 + + P G Sbjct: 435 ECLSNPCLNG 444 >AF243129-1|AAK61830.1| 3494|Homo sapiens intrinsic factor-vitamin B12 receptor protein. Length = 3494 Score = 53.2 bits (122), Expect = 6e-07 Identities = 29/84 (34%), Positives = 40/84 (47%), Gaps = 1/84 (1%) Frame = +2 Query: 209 VQNCFTCAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLC-GPGKCMN 385 VQ C + CLN G C + ++ GY C C G+ G NC C C G C++ Sbjct: 264 VQLSNICLSHPCLN-GQCIDTVS--GYFCKCDSGWTGVNCTENINECLSNPCLNGGTCVD 320 Query: 386 TADSYKCACPVTYTGKNCEVKQLI 457 DS+ C C +TG C+V Q + Sbjct: 321 GVDSFSCECTRLWTGALCQVPQQV 344 Score = 46.0 bits (104), Expect = 8e-05 Identities = 21/70 (30%), Positives = 32/70 (45%), Gaps = 7/70 (10%) Frame = +2 Query: 290 VCLCAPGFGGNN-----CDRIGESCRPGLCGPGKCMNTADSYKCACPVTYTGKNC--EVK 448 +C C PG+ GN C ++ C C G+C++T Y C C +TG NC + Sbjct: 246 LCTCLPGYTGNGYGPNGCVQLSNICLSHPCLNGQCIDTVSGYFCKCDSGWTGVNCTENIN 305 Query: 449 QLIEYPAFTG 478 + + P G Sbjct: 306 ECLSNPCLNG 315 Score = 45.2 bits (102), Expect = 1e-04 Identities = 26/80 (32%), Positives = 31/80 (38%), Gaps = 6/80 (7%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCR-----PGLC-GPGKCMNT 388 C+ N C N G C + C+C P + G C C P C G C+NT Sbjct: 7 CSSNPCQNGGNCLNL--HDSFFCICPPQWKGPLCSADVNECEIYSGTPLSCQNGGTCVNT 64 Query: 389 ADSYKCACPVTYTGKNCEVK 448 SY C CP G C K Sbjct: 65 MGSYSCHCPPETYGPQCASK 84 >AF034611-1|AAC82612.1| 3623|Homo sapiens intrinsic factor-B12 receptor precursor protein. Length = 3623 Score = 53.2 bits (122), Expect = 6e-07 Identities = 29/84 (34%), Positives = 40/84 (47%), Gaps = 1/84 (1%) Frame = +2 Query: 209 VQNCFTCAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLC-GPGKCMN 385 VQ C + CLN G C + ++ GY C C G+ G NC C C G C++ Sbjct: 393 VQLSNICLSHPCLN-GQCIDTVS--GYFCKCDSGWTGVNCTENINECLSNPCLNGGTCVD 449 Query: 386 TADSYKCACPVTYTGKNCEVKQLI 457 DS+ C C +TG C+V Q + Sbjct: 450 GVDSFSCECTRLWTGALCQVPQQV 473 Score = 46.0 bits (104), Expect = 8e-05 Identities = 21/70 (30%), Positives = 32/70 (45%), Gaps = 7/70 (10%) Frame = +2 Query: 290 VCLCAPGFGGNN-----CDRIGESCRPGLCGPGKCMNTADSYKCACPVTYTGKNC--EVK 448 +C C PG+ GN C ++ C C G+C++T Y C C +TG NC + Sbjct: 375 LCTCLPGYTGNGYGPNGCVQLSNICLSHPCLNGQCIDTVSGYFCKCDSGWTGVNCTENIN 434 Query: 449 QLIEYPAFTG 478 + + P G Sbjct: 435 ECLSNPCLNG 444 Score = 45.2 bits (102), Expect = 1e-04 Identities = 26/80 (32%), Positives = 31/80 (38%), Gaps = 6/80 (7%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCR-----PGLC-GPGKCMNT 388 C+ N C N G C + C+C P + G C C P C G C+NT Sbjct: 136 CSSNPCQNGGNCLNL--HDSFFCICPPQWKGPLCSADVNECEIYSGTPLSCQNGGTCVNT 193 Query: 389 ADSYKCACPVTYTGKNCEVK 448 SY C CP G C K Sbjct: 194 MGSYSCHCPPETYGPQCASK 213 >L38969-1|AAC41762.1| 956|Homo sapiens thrombospondin 3 protein. Length = 956 Score = 52.0 bits (119), Expect = 1e-06 Identities = 29/73 (39%), Positives = 33/73 (45%), Gaps = 5/73 (6%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVC-LCAPGFGGN--NCDRIGESCRPGLCGPG-KCMNTAD 394 C+PN C C E GY C C PG GN +C I E C PG C+NT Sbjct: 278 CSPNPCFRGVDCMEVYEYPGYRCGPCPPGLQGNGTHCSDINECAHADPCFPGSSCINTMP 337 Query: 395 SYKC-ACPVTYTG 430 + C ACP Y G Sbjct: 338 GFHCEACPRGYKG 350 >BC113847-1|AAI13848.1| 956|Homo sapiens thrombospondin 3, precursor protein. Length = 956 Score = 52.0 bits (119), Expect = 1e-06 Identities = 29/73 (39%), Positives = 33/73 (45%), Gaps = 5/73 (6%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVC-LCAPGFGGN--NCDRIGESCRPGLCGPG-KCMNTAD 394 C+PN C C E GY C C PG GN +C I E C PG C+NT Sbjct: 278 CSPNPCFRGVDCMEVYEYPGYRCGPCPPGLQGNGTHCSDINECAHADPCFPGSSCINTMP 337 Query: 395 SYKC-ACPVTYTG 430 + C ACP Y G Sbjct: 338 GFHCEACPRGYKG 350 >AL713999-15|CAI95084.1| 956|Homo sapiens thrombospondin 3 protein. Length = 956 Score = 52.0 bits (119), Expect = 1e-06 Identities = 29/73 (39%), Positives = 33/73 (45%), Gaps = 5/73 (6%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVC-LCAPGFGGN--NCDRIGESCRPGLCGPG-KCMNTAD 394 C+PN C C E GY C C PG GN +C I E C PG C+NT Sbjct: 278 CSPNPCFRGVDCMEVYEYPGYRCGPCPPGLQGNGTHCSDINECAHADPCFPGSSCINTMP 337 Query: 395 SYKC-ACPVTYTG 430 + C ACP Y G Sbjct: 338 GFHCEACPRGYKG 350 >AK223278-1|BAD96998.1| 956|Homo sapiens thrombospondin 3 precursor variant protein. Length = 956 Score = 52.0 bits (119), Expect = 1e-06 Identities = 29/73 (39%), Positives = 33/73 (45%), Gaps = 5/73 (6%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVC-LCAPGFGGN--NCDRIGESCRPGLCGPG-KCMNTAD 394 C+PN C C E GY C C PG GN +C I E C PG C+NT Sbjct: 278 CSPNPCFRGVDCMEVYEYPGYRCGPCPPGLQGNGTHCSDINECAHADPCFPGSSCINTMP 337 Query: 395 SYKC-ACPVTYTG 430 + C ACP Y G Sbjct: 338 GFHCEACPRGYKG 350 >AF023268-6|AAC51818.1| 736|Homo sapiens thrombospondin3 protein. Length = 736 Score = 52.0 bits (119), Expect = 1e-06 Identities = 29/73 (39%), Positives = 33/73 (45%), Gaps = 5/73 (6%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVC-LCAPGFGGN--NCDRIGESCRPGLCGPG-KCMNTAD 394 C+PN C C E GY C C PG GN +C I E C PG C+NT Sbjct: 278 CSPNPCFRGVDCMEVYEYPGYRCGPCPPGLQGNGTHCSDINECAHADPCFPGSSCINTMP 337 Query: 395 SYKC-ACPVTYTG 430 + C ACP Y G Sbjct: 338 GFHCEACPRGYKG 350 >AB076400-1|BAB86868.1| 1097|Homo sapiens fat3 protein. Length = 1097 Score = 52.0 bits (119), Expect = 1e-06 Identities = 37/118 (31%), Positives = 48/118 (40%), Gaps = 12/118 (10%) Frame = +2 Query: 125 SGFVGCISMLILGNEE---KNIMALALE----KENVQNCF----TCAPNLCLNNGVCQEA 271 SGF GC+ +IL N E +N + E E C C + C + G C Sbjct: 488 SGFQGCLDSVILNNNELPLQNKRSSFAEVVGLTELKLGCVLYPDACKRSPCQHGGSCT-G 546 Query: 272 LTEHGYVCLCAPGFGGNNCDRIGESCRPGLC-GPGKCMNTADSYKCACPVTYTGKNCE 442 L GY C C F G NC+ +C P C G C +++ C C TG CE Sbjct: 547 LPSGGYQCTCLSQFTGRNCESEITACFPNPCRNGGSCDPIGNTFICNCKAGLTGVTCE 604 Score = 49.6 bits (113), Expect = 7e-06 Identities = 23/78 (29%), Positives = 34/78 (43%), Gaps = 1/78 (1%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLC-GPGKCMNTADSYK 403 C PN C N G C + ++C C G G C+ C C G C+N S+ Sbjct: 572 CFPNPCRNGGSCDPI--GNTFICNCKAGLTGVTCEEDINECEREECENGGSCVNVFGSFL 629 Query: 404 CACPVTYTGKNCEVKQLI 457 C C Y G+ C ++ ++ Sbjct: 630 CNCTPGYVGQYCGLRPVV 647 >M34057-1|AAA61160.1| 1394|Homo sapiens TGFB1 protein. Length = 1394 Score = 51.6 bits (118), Expect = 2e-06 Identities = 25/71 (35%), Positives = 39/71 (54%), Gaps = 4/71 (5%) Frame = +2 Query: 206 NVQNCFTCAPNLCLNNGVCQEALTEHGYVCLCAPGF----GGNNCDRIGESCRPGLCGPG 373 ++ C T +LC + G C+ TE ++C+C GF G NC + E RP +CG G Sbjct: 588 DIDEC-TQVQHLC-SQGRCEN--TEGSFLCICPAGFMASEEGTNCIDVDECLRPDVCGEG 643 Query: 374 KCMNTADSYKC 406 C+NT +++C Sbjct: 644 HCVNTVGAFRC 654 Score = 51.6 bits (118), Expect = 2e-06 Identities = 31/81 (38%), Positives = 38/81 (46%), Gaps = 12/81 (14%) Frame = +2 Query: 236 NLCLNN-GVCQEA---LTEHGYVCLCAPGF---GGNNCDRIGESCRPGLCGP-GKCMNTA 391 N CL + VCQ T Y C C GF C I E PGLCGP G+C+NT Sbjct: 836 NECLEDKSVCQRGDCINTAGSYDCTCPDGFQLDDNKTCQDINECEHPGLCGPQGECLNTE 895 Query: 392 DSYKCAC----PVTYTGKNCE 442 S+ C C ++ G+ CE Sbjct: 896 GSFHCVCQQGFSISADGRTCE 916 Score = 49.2 bits (112), Expect = 9e-06 Identities = 30/105 (28%), Positives = 47/105 (44%), Gaps = 8/105 (7%) Frame = +2 Query: 188 LALEKENVQNCFTCAPNLCLNNGVCQEALTEHGYVCLCAPGFG----GNNCDRIGESCRP 355 L+ K+ ++ C +G C+ TE + C+C G+ G++C+ I E Sbjct: 784 LSAAKDQCEDIDECQHRHLCAHGQCRN--TEGSFQCVCDQGYRASGLGDHCEDINECLED 841 Query: 356 -GLCGPGKCMNTADSYKCACPVTY---TGKNCEVKQLIEYPAFTG 478 +C G C+NTA SY C CP + K C+ E+P G Sbjct: 842 KSVCQRGDCINTAGSYDCTCPDGFQLDDNKTCQDINECEHPGLCG 886 Score = 46.4 bits (105), Expect = 6e-05 Identities = 27/77 (35%), Positives = 37/77 (48%), Gaps = 8/77 (10%) Frame = +2 Query: 236 NLCLNNGVCQEALTEHGYVCLCAPGF----GGNNCDRIGESCRPGLCGPGKCMNTADSYK 403 NLC+N G C+ TE + C C G+ + C+ I E LC G+C NT S++ Sbjct: 760 NLCVN-GQCKN--TEGSFRCTCGQGYQLSAAKDQCEDIDECQHRHLCAHGQCRNTEGSFQ 816 Query: 404 CACPVTY----TGKNCE 442 C C Y G +CE Sbjct: 817 CVCDQGYRASGLGDHCE 833 Score = 45.2 bits (102), Expect = 1e-04 Identities = 25/68 (36%), Positives = 32/68 (47%), Gaps = 6/68 (8%) Frame = +2 Query: 242 CLNNGVC--QEALTEHG-YVCL-CAPGFGGNN--CDRIGESCRPGLCGPGKCMNTADSYK 403 CLN C ++ + G Y C+ C GF G N C + E P +C G C N SY Sbjct: 675 CLNPSTCPDEQCVNSPGSYQCVPCTEGFRGWNGQCLDVDECLEPNVCANGDCSNLEGSYM 734 Query: 404 CACPVTYT 427 C+C YT Sbjct: 735 CSCHKGYT 742 Score = 44.0 bits (99), Expect = 3e-04 Identities = 21/60 (35%), Positives = 31/60 (51%), Gaps = 5/60 (8%) Frame = +2 Query: 260 CQEALTEHGY--VCLCAPGFGGNN---CDRIGESCRPGLCGPGKCMNTADSYKCACPVTY 424 C + + HGY + C PG+ N C I E G+C G+C+NT SY+C C + + Sbjct: 271 CPKKPSYHGYNQMMECLPGYKRVNNTFCQDINECQLQGVCPNGECLNTMGSYRCTCKIGF 330 Score = 43.2 bits (97), Expect = 6e-04 Identities = 24/68 (35%), Positives = 32/68 (47%), Gaps = 4/68 (5%) Frame = +2 Query: 233 PNLCLNNGVCQEALTEHGYVCLCAPGF----GGNNCDRIGESCRPGLCGPGKCMNTADSY 400 PN+C N G C E Y+C C G+ +C I E + LC G+C NT S+ Sbjct: 718 PNVCAN-GDCSNL--EGSYMCSCHKGYTRTPDHKHCRDIDECQQGNLCVNGQCKNTEGSF 774 Query: 401 KCACPVTY 424 +C C Y Sbjct: 775 RCTCGQGY 782 Score = 39.5 bits (88), Expect = 0.007 Identities = 23/74 (31%), Positives = 30/74 (40%), Gaps = 4/74 (5%) Frame = +2 Query: 203 ENVQNCFTCAPNLCLNNGVCQEALTEHGYVCLCAPGFGGN----NCDRIGESCRPGLCGP 370 ++ C +C NG C T GY C C G + C + E P C Sbjct: 1096 KDADECLLFGQEIC-KNGFCLN--TRPGYECYCKQGTYYDPVKLQCFDMDECQDPSSCID 1152 Query: 371 GKCMNTADSYKCAC 412 G+C+NT SY C C Sbjct: 1153 GQCVNTEGSYNCFC 1166 Score = 39.1 bits (87), Expect = 0.010 Identities = 24/64 (37%), Positives = 27/64 (42%), Gaps = 10/64 (15%) Frame = +2 Query: 251 NGVCQEALTEHGYVCLCAPG----------FGGNNCDRIGESCRPGLCGPGKCMNTADSY 400 NG C + GY C C G F N CD + R LC KC+NT SY Sbjct: 1306 NGRCVRV--QEGYTCDCLDGYHLDTAKMTCFDVNECDELNN--RMSLCKNAKCINTDGSY 1361 Query: 401 KCAC 412 KC C Sbjct: 1362 KCLC 1365 Score = 36.7 bits (81), Expect = 0.052 Identities = 22/66 (33%), Positives = 27/66 (40%), Gaps = 9/66 (13%) Frame = +2 Query: 242 CLNNGVCQEA----LTEHGYVCLCAPGF----GGNNCDRIGE-SCRPGLCGPGKCMNTAD 394 C+NN VC T + CLC GF G C + E G+CG C N Sbjct: 921 CVNNTVCDSHGFCDNTAGSFRCLCYQGFQAPQDGQGCVDVNECELLSGVCGEAFCENVEG 980 Query: 395 SYKCAC 412 S+ C C Sbjct: 981 SFLCVC 986 Score = 35.5 bits (78), Expect = 0.12 Identities = 26/86 (30%), Positives = 36/86 (41%), Gaps = 9/86 (10%) Frame = +2 Query: 209 VQNCFTCAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNN----CDRIGESCR-PGLCGPG 373 + C T P++C G C Y C+C G+ + C I E + LC G Sbjct: 547 INEC-TVNPDIC-GAGHCINLPVR--YTCICYEGYRFSEQQRKCVDIDECTQVQHLCSQG 602 Query: 374 KCMNTADSYKCACPVTY----TGKNC 439 +C NT S+ C CP + G NC Sbjct: 603 RCENTEGSFLCICPAGFMASEEGTNC 628 Score = 31.5 bits (68), Expect = 1.9 Identities = 22/73 (30%), Positives = 30/73 (41%), Gaps = 8/73 (10%) Frame = +2 Query: 242 CLNNGVCQEAL---TEHGYVC-LCAPGFG---GNNCDRIGESCRPGLCGPGKCMNTADSY 400 CL VC E T + C C G+ C+ I E P C +C+N+ SY Sbjct: 634 CLRPDVCGEGHCVNTVGAFRCEYCDSGYRMTQRGRCEDIDECLNPSTCPDEQCVNSPGSY 693 Query: 401 KCA-CPVTYTGKN 436 +C C + G N Sbjct: 694 QCVPCTEGFRGWN 706 >BC130289-1|AAI30290.1| 1395|Homo sapiens latent transforming growth factor beta binding protein 1 protein. Length = 1395 Score = 51.6 bits (118), Expect = 2e-06 Identities = 25/71 (35%), Positives = 39/71 (54%), Gaps = 4/71 (5%) Frame = +2 Query: 206 NVQNCFTCAPNLCLNNGVCQEALTEHGYVCLCAPGF----GGNNCDRIGESCRPGLCGPG 373 ++ C T +LC + G C+ TE ++C+C GF G NC + E RP +CG G Sbjct: 589 DIDEC-TQVQHLC-SQGRCEN--TEGSFLCICPAGFMASEEGTNCIDVDECLRPDVCGEG 644 Query: 374 KCMNTADSYKC 406 C+NT +++C Sbjct: 645 HCVNTVGAFRC 655 Score = 51.6 bits (118), Expect = 2e-06 Identities = 31/81 (38%), Positives = 38/81 (46%), Gaps = 12/81 (14%) Frame = +2 Query: 236 NLCLNN-GVCQEA---LTEHGYVCLCAPGF---GGNNCDRIGESCRPGLCGP-GKCMNTA 391 N CL + VCQ T Y C C GF C I E PGLCGP G+C+NT Sbjct: 837 NECLEDKSVCQRGDCINTAGSYDCTCPDGFQLDDNKTCQDINECEHPGLCGPQGECLNTE 896 Query: 392 DSYKCAC----PVTYTGKNCE 442 S+ C C ++ G+ CE Sbjct: 897 GSFHCVCQQGFSISADGRTCE 917 Score = 49.2 bits (112), Expect = 9e-06 Identities = 30/105 (28%), Positives = 47/105 (44%), Gaps = 8/105 (7%) Frame = +2 Query: 188 LALEKENVQNCFTCAPNLCLNNGVCQEALTEHGYVCLCAPGFG----GNNCDRIGESCRP 355 L+ K+ ++ C +G C+ TE + C+C G+ G++C+ I E Sbjct: 785 LSAAKDQCEDIDECQHRHLCAHGQCRN--TEGSFQCVCDQGYRASGLGDHCEDINECLED 842 Query: 356 -GLCGPGKCMNTADSYKCACPVTY---TGKNCEVKQLIEYPAFTG 478 +C G C+NTA SY C CP + K C+ E+P G Sbjct: 843 KSVCQRGDCINTAGSYDCTCPDGFQLDDNKTCQDINECEHPGLCG 887 Score = 46.4 bits (105), Expect = 6e-05 Identities = 27/77 (35%), Positives = 37/77 (48%), Gaps = 8/77 (10%) Frame = +2 Query: 236 NLCLNNGVCQEALTEHGYVCLCAPGF----GGNNCDRIGESCRPGLCGPGKCMNTADSYK 403 NLC+N G C+ TE + C C G+ + C+ I E LC G+C NT S++ Sbjct: 761 NLCVN-GQCKN--TEGSFRCTCGQGYQLSAAKDQCEDIDECQHRHLCAHGQCRNTEGSFQ 817 Query: 404 CACPVTY----TGKNCE 442 C C Y G +CE Sbjct: 818 CVCDQGYRASGLGDHCE 834 Score = 45.2 bits (102), Expect = 1e-04 Identities = 25/68 (36%), Positives = 32/68 (47%), Gaps = 6/68 (8%) Frame = +2 Query: 242 CLNNGVC--QEALTEHG-YVCL-CAPGFGGNN--CDRIGESCRPGLCGPGKCMNTADSYK 403 CLN C ++ + G Y C+ C GF G N C + E P +C G C N SY Sbjct: 676 CLNPSTCPDEQCVNSPGSYQCVPCTEGFRGWNGQCLDVDECLEPNVCANGDCSNLEGSYM 735 Query: 404 CACPVTYT 427 C+C YT Sbjct: 736 CSCHKGYT 743 Score = 44.0 bits (99), Expect = 3e-04 Identities = 21/60 (35%), Positives = 31/60 (51%), Gaps = 5/60 (8%) Frame = +2 Query: 260 CQEALTEHGY--VCLCAPGFGGNN---CDRIGESCRPGLCGPGKCMNTADSYKCACPVTY 424 C + + HGY + C PG+ N C I E G+C G+C+NT SY+C C + + Sbjct: 271 CPKKPSYHGYNQMMECLPGYKRVNNTFCQDINECQLQGVCPNGECLNTMGSYRCTCKIGF 330 Score = 43.2 bits (97), Expect = 6e-04 Identities = 24/68 (35%), Positives = 32/68 (47%), Gaps = 4/68 (5%) Frame = +2 Query: 233 PNLCLNNGVCQEALTEHGYVCLCAPGF----GGNNCDRIGESCRPGLCGPGKCMNTADSY 400 PN+C N G C E Y+C C G+ +C I E + LC G+C NT S+ Sbjct: 719 PNVCAN-GDCSNL--EGSYMCSCHKGYTRTPDHKHCRDIDECQQGNLCVNGQCKNTEGSF 775 Query: 401 KCACPVTY 424 +C C Y Sbjct: 776 RCTCGQGY 783 Score = 39.5 bits (88), Expect = 0.007 Identities = 23/74 (31%), Positives = 30/74 (40%), Gaps = 4/74 (5%) Frame = +2 Query: 203 ENVQNCFTCAPNLCLNNGVCQEALTEHGYVCLCAPGFGGN----NCDRIGESCRPGLCGP 370 ++ C +C NG C T GY C C G + C + E P C Sbjct: 1097 KDADECLLFGQEIC-KNGFCLN--TRPGYECYCKQGTYYDPVKLQCFDMDECQDPSSCID 1153 Query: 371 GKCMNTADSYKCAC 412 G+C+NT SY C C Sbjct: 1154 GQCVNTEGSYNCFC 1167 Score = 37.5 bits (83), Expect = 0.029 Identities = 23/64 (35%), Positives = 27/64 (42%), Gaps = 10/64 (15%) Frame = +2 Query: 251 NGVCQEALTEHGYVCLCAPGF----------GGNNCDRIGESCRPGLCGPGKCMNTADSY 400 NG C + GY C C G+ N CD + R LC KC+NT SY Sbjct: 1307 NGRCVRV--QEGYTCDCFDGYHLDTAKMTCVDVNECDELNN--RMSLCKNAKCINTDGSY 1362 Query: 401 KCAC 412 KC C Sbjct: 1363 KCLC 1366 Score = 36.7 bits (81), Expect = 0.052 Identities = 22/66 (33%), Positives = 27/66 (40%), Gaps = 9/66 (13%) Frame = +2 Query: 242 CLNNGVCQEA----LTEHGYVCLCAPGF----GGNNCDRIGE-SCRPGLCGPGKCMNTAD 394 C+NN VC T + CLC GF G C + E G+CG C N Sbjct: 922 CVNNTVCDSHGFCDNTAGSFRCLCYQGFQAPQDGQGCVDVNECELLSGVCGEAFCENVEG 981 Query: 395 SYKCAC 412 S+ C C Sbjct: 982 SFLCVC 987 Score = 35.5 bits (78), Expect = 0.12 Identities = 26/86 (30%), Positives = 36/86 (41%), Gaps = 9/86 (10%) Frame = +2 Query: 209 VQNCFTCAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNN----CDRIGESCR-PGLCGPG 373 + C T P++C G C Y C+C G+ + C I E + LC G Sbjct: 548 INEC-TVNPDIC-GAGHCINLPVR--YTCICYEGYRFSEQQRKCVDIDECTQVQHLCSQG 603 Query: 374 KCMNTADSYKCACPVTY----TGKNC 439 +C NT S+ C CP + G NC Sbjct: 604 RCENTEGSFLCICPAGFMASEEGTNC 629 Score = 31.5 bits (68), Expect = 1.9 Identities = 22/73 (30%), Positives = 30/73 (41%), Gaps = 8/73 (10%) Frame = +2 Query: 242 CLNNGVCQEAL---TEHGYVC-LCAPGFG---GNNCDRIGESCRPGLCGPGKCMNTADSY 400 CL VC E T + C C G+ C+ I E P C +C+N+ SY Sbjct: 635 CLRPDVCGEGHCVNTVGAFRCEYCDSGYRMTQRGRCEDIDECLNPSTCPDEQCVNSPGSY 694 Query: 401 KCA-CPVTYTGKN 436 +C C + G N Sbjct: 695 QCVPCTEGFRGWN 707 >AF489528-1|AAM03124.1| 1394|Homo sapiens transforming growth factor-beta binding protein-1S protein. Length = 1394 Score = 51.6 bits (118), Expect = 2e-06 Identities = 25/71 (35%), Positives = 39/71 (54%), Gaps = 4/71 (5%) Frame = +2 Query: 206 NVQNCFTCAPNLCLNNGVCQEALTEHGYVCLCAPGF----GGNNCDRIGESCRPGLCGPG 373 ++ C T +LC + G C+ TE ++C+C GF G NC + E RP +CG G Sbjct: 588 DIDEC-TQVQHLC-SQGRCEN--TEGSFLCICPAGFMASEEGTNCIDVDECLRPDVCGEG 643 Query: 374 KCMNTADSYKC 406 C+NT +++C Sbjct: 644 HCVNTVGAFRC 654 Score = 51.6 bits (118), Expect = 2e-06 Identities = 31/81 (38%), Positives = 38/81 (46%), Gaps = 12/81 (14%) Frame = +2 Query: 236 NLCLNN-GVCQEA---LTEHGYVCLCAPGF---GGNNCDRIGESCRPGLCGP-GKCMNTA 391 N CL + VCQ T Y C C GF C I E PGLCGP G+C+NT Sbjct: 836 NECLEDKSVCQRGDCINTAGSYDCTCPDGFQLDDNKTCQDINECEHPGLCGPQGECLNTE 895 Query: 392 DSYKCAC----PVTYTGKNCE 442 S+ C C ++ G+ CE Sbjct: 896 GSFHCVCQQGFSISADGRTCE 916 Score = 49.2 bits (112), Expect = 9e-06 Identities = 30/105 (28%), Positives = 47/105 (44%), Gaps = 8/105 (7%) Frame = +2 Query: 188 LALEKENVQNCFTCAPNLCLNNGVCQEALTEHGYVCLCAPGFG----GNNCDRIGESCRP 355 L+ K+ ++ C +G C+ TE + C+C G+ G++C+ I E Sbjct: 784 LSAAKDQCEDIDECQHRHLCAHGQCRN--TEGSFQCVCDQGYRASGLGDHCEDINECLED 841 Query: 356 -GLCGPGKCMNTADSYKCACPVTY---TGKNCEVKQLIEYPAFTG 478 +C G C+NTA SY C CP + K C+ E+P G Sbjct: 842 KSVCQRGDCINTAGSYDCTCPDGFQLDDNKTCQDINECEHPGLCG 886 Score = 46.4 bits (105), Expect = 6e-05 Identities = 27/77 (35%), Positives = 37/77 (48%), Gaps = 8/77 (10%) Frame = +2 Query: 236 NLCLNNGVCQEALTEHGYVCLCAPGF----GGNNCDRIGESCRPGLCGPGKCMNTADSYK 403 NLC+N G C+ TE + C C G+ + C+ I E LC G+C NT S++ Sbjct: 760 NLCVN-GQCKN--TEGSFRCTCGQGYQLSAAKDQCEDIDECQHRHLCAHGQCRNTEGSFQ 816 Query: 404 CACPVTY----TGKNCE 442 C C Y G +CE Sbjct: 817 CVCDQGYRASGLGDHCE 833 Score = 45.2 bits (102), Expect = 1e-04 Identities = 25/68 (36%), Positives = 32/68 (47%), Gaps = 6/68 (8%) Frame = +2 Query: 242 CLNNGVC--QEALTEHG-YVCL-CAPGFGGNN--CDRIGESCRPGLCGPGKCMNTADSYK 403 CLN C ++ + G Y C+ C GF G N C + E P +C G C N SY Sbjct: 675 CLNPSTCPDEQCVNSPGSYQCVPCTEGFRGWNGQCLDVDECLEPNVCANGDCSNLEGSYM 734 Query: 404 CACPVTYT 427 C+C YT Sbjct: 735 CSCHKGYT 742 Score = 44.0 bits (99), Expect = 3e-04 Identities = 21/60 (35%), Positives = 31/60 (51%), Gaps = 5/60 (8%) Frame = +2 Query: 260 CQEALTEHGY--VCLCAPGFGGNN---CDRIGESCRPGLCGPGKCMNTADSYKCACPVTY 424 C + + HGY + C PG+ N C I E G+C G+C+NT SY+C C + + Sbjct: 271 CPKKPSYHGYNQMMECLPGYKRVNNTFCQDINECQLQGVCPNGECLNTMGSYRCTCKIGF 330 Score = 43.2 bits (97), Expect = 6e-04 Identities = 24/68 (35%), Positives = 32/68 (47%), Gaps = 4/68 (5%) Frame = +2 Query: 233 PNLCLNNGVCQEALTEHGYVCLCAPGF----GGNNCDRIGESCRPGLCGPGKCMNTADSY 400 PN+C N G C E Y+C C G+ +C I E + LC G+C NT S+ Sbjct: 718 PNVCAN-GDCSNL--EGSYMCSCHKGYTRTPDHKHCRDIDECQQGNLCVNGQCKNTEGSF 774 Query: 401 KCACPVTY 424 +C C Y Sbjct: 775 RCTCGQGY 782 Score = 39.5 bits (88), Expect = 0.007 Identities = 23/74 (31%), Positives = 30/74 (40%), Gaps = 4/74 (5%) Frame = +2 Query: 203 ENVQNCFTCAPNLCLNNGVCQEALTEHGYVCLCAPGFGGN----NCDRIGESCRPGLCGP 370 ++ C +C NG C T GY C C G + C + E P C Sbjct: 1096 KDADECLLFGQEIC-KNGFCLN--TRPGYECYCKQGTYYDPVKLQCFDMDECQDPSSCID 1152 Query: 371 GKCMNTADSYKCAC 412 G+C+NT SY C C Sbjct: 1153 GQCVNTEGSYNCFC 1166 Score = 37.9 bits (84), Expect = 0.022 Identities = 23/64 (35%), Positives = 27/64 (42%), Gaps = 10/64 (15%) Frame = +2 Query: 251 NGVCQEALTEHGYVCLCAPGF----------GGNNCDRIGESCRPGLCGPGKCMNTADSY 400 NG C + GY C C G+ N CD + R LC KC+NT SY Sbjct: 1306 NGRCVRV--QEGYTCDCLDGYHLDTAKMTCVDVNECDELNN--RMSLCKNAKCINTDGSY 1361 Query: 401 KCAC 412 KC C Sbjct: 1362 KCLC 1365 Score = 36.7 bits (81), Expect = 0.052 Identities = 22/66 (33%), Positives = 27/66 (40%), Gaps = 9/66 (13%) Frame = +2 Query: 242 CLNNGVCQEA----LTEHGYVCLCAPGF----GGNNCDRIGE-SCRPGLCGPGKCMNTAD 394 C+NN VC T + CLC GF G C + E G+CG C N Sbjct: 921 CVNNTVCDSHGFCDNTAGSFRCLCYQGFQAPQDGQGCVDVNECELLSGVCGEAFCENVEG 980 Query: 395 SYKCAC 412 S+ C C Sbjct: 981 SFLCVC 986 Score = 35.5 bits (78), Expect = 0.12 Identities = 26/86 (30%), Positives = 36/86 (41%), Gaps = 9/86 (10%) Frame = +2 Query: 209 VQNCFTCAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNN----CDRIGESCR-PGLCGPG 373 + C T P++C G C Y C+C G+ + C I E + LC G Sbjct: 547 INEC-TVNPDIC-GAGHCINLPVR--YTCICYEGYRFSEQQRKCVDIDECTQVQHLCSQG 602 Query: 374 KCMNTADSYKCACPVTY----TGKNC 439 +C NT S+ C CP + G NC Sbjct: 603 RCENTEGSFLCICPAGFMASEEGTNC 628 Score = 31.5 bits (68), Expect = 1.9 Identities = 22/73 (30%), Positives = 30/73 (41%), Gaps = 8/73 (10%) Frame = +2 Query: 242 CLNNGVCQEAL---TEHGYVC-LCAPGFG---GNNCDRIGESCRPGLCGPGKCMNTADSY 400 CL VC E T + C C G+ C+ I E P C +C+N+ SY Sbjct: 634 CLRPDVCGEGHCVNTVGAFRCEYCDSGYRMTQRGRCEDIDECLNPSTCPDEQCVNSPGSY 693 Query: 401 KCA-CPVTYTGKN 436 +C C + G N Sbjct: 694 QCVPCTEGFRGWN 706 >AF026547-1|AAC80576.1| 1321|Homo sapiens neurocan protein. Length = 1321 Score = 51.6 bits (118), Expect = 2e-06 Identities = 25/73 (34%), Positives = 34/73 (46%), Gaps = 1/73 (1%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLC-GPGKCMNTADSYK 403 C N CL+ G C T +G C C GF G NC+ + C C G C++ + + Sbjct: 1012 CENNPCLHGGTCNANGTMYG--CSCDQGFAGENCEIDIDDCLCSPCENGGTCIDEVNGFV 1069 Query: 404 CACPVTYTGKNCE 442 C C +Y G CE Sbjct: 1070 CLCLPSYGGSFCE 1082 Score = 44.0 bits (99), Expect = 3e-04 Identities = 19/51 (37%), Positives = 31/51 (60%) Frame = +2 Query: 206 NVQNCFTCAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPG 358 ++ +C C+P C N G C + + +G+VCLC P +GG+ C++ E C G Sbjct: 1046 DIDDCL-CSP--CENGGTCIDEV--NGFVCLCLPSYGGSFCEKDTEGCDRG 1091 >AC019127-1|AAY24260.1| 697|Homo sapiens unknown protein. Length = 697 Score = 51.6 bits (118), Expect = 2e-06 Identities = 25/71 (35%), Positives = 39/71 (54%), Gaps = 4/71 (5%) Frame = +2 Query: 206 NVQNCFTCAPNLCLNNGVCQEALTEHGYVCLCAPGF----GGNNCDRIGESCRPGLCGPG 373 ++ C T +LC + G C+ TE ++C+C GF G NC + E RP +CG G Sbjct: 42 DIDEC-TQVQHLC-SQGRCEN--TEGSFLCICPAGFMASEEGTNCIDVDECLRPDVCGEG 97 Query: 374 KCMNTADSYKC 406 C+NT +++C Sbjct: 98 HCVNTVGAFRC 108 Score = 51.6 bits (118), Expect = 2e-06 Identities = 31/81 (38%), Positives = 38/81 (46%), Gaps = 12/81 (14%) Frame = +2 Query: 236 NLCLNN-GVCQEA---LTEHGYVCLCAPGF---GGNNCDRIGESCRPGLCGP-GKCMNTA 391 N CL + VCQ T Y C C GF C I E PGLCGP G+C+NT Sbjct: 290 NECLEDKSVCQRGDCINTAGSYDCTCPDGFQLDDNKTCQDINECEHPGLCGPQGECLNTE 349 Query: 392 DSYKCAC----PVTYTGKNCE 442 S+ C C ++ G+ CE Sbjct: 350 GSFHCVCQQGFSISADGRTCE 370 Score = 49.2 bits (112), Expect = 9e-06 Identities = 30/105 (28%), Positives = 47/105 (44%), Gaps = 8/105 (7%) Frame = +2 Query: 188 LALEKENVQNCFTCAPNLCLNNGVCQEALTEHGYVCLCAPGFG----GNNCDRIGESCRP 355 L+ K+ ++ C +G C+ TE + C+C G+ G++C+ I E Sbjct: 238 LSAAKDQCEDIDECQHRHLCAHGQCRN--TEGSFQCVCDQGYRASGLGDHCEDINECLED 295 Query: 356 -GLCGPGKCMNTADSYKCACPVTY---TGKNCEVKQLIEYPAFTG 478 +C G C+NTA SY C CP + K C+ E+P G Sbjct: 296 KSVCQRGDCINTAGSYDCTCPDGFQLDDNKTCQDINECEHPGLCG 340 Score = 46.4 bits (105), Expect = 6e-05 Identities = 27/77 (35%), Positives = 37/77 (48%), Gaps = 8/77 (10%) Frame = +2 Query: 236 NLCLNNGVCQEALTEHGYVCLCAPGF----GGNNCDRIGESCRPGLCGPGKCMNTADSYK 403 NLC+N G C+ TE + C C G+ + C+ I E LC G+C NT S++ Sbjct: 214 NLCVN-GQCKN--TEGSFRCTCGQGYQLSAAKDQCEDIDECQHRHLCAHGQCRNTEGSFQ 270 Query: 404 CACPVTY----TGKNCE 442 C C Y G +CE Sbjct: 271 CVCDQGYRASGLGDHCE 287 Score = 45.2 bits (102), Expect = 1e-04 Identities = 25/68 (36%), Positives = 32/68 (47%), Gaps = 6/68 (8%) Frame = +2 Query: 242 CLNNGVC--QEALTEHG-YVCL-CAPGFGGNN--CDRIGESCRPGLCGPGKCMNTADSYK 403 CLN C ++ + G Y C+ C GF G N C + E P +C G C N SY Sbjct: 129 CLNPSTCPDEQCVNSPGSYQCVPCTEGFRGWNGQCLDVDECLEPNVCANGDCSNLEGSYM 188 Query: 404 CACPVTYT 427 C+C YT Sbjct: 189 CSCHKGYT 196 Score = 43.2 bits (97), Expect = 6e-04 Identities = 24/68 (35%), Positives = 32/68 (47%), Gaps = 4/68 (5%) Frame = +2 Query: 233 PNLCLNNGVCQEALTEHGYVCLCAPGF----GGNNCDRIGESCRPGLCGPGKCMNTADSY 400 PN+C N G C E Y+C C G+ +C I E + LC G+C NT S+ Sbjct: 172 PNVCAN-GDCSNL--EGSYMCSCHKGYTRTPDHKHCRDIDECQQGNLCVNGQCKNTEGSF 228 Query: 401 KCACPVTY 424 +C C Y Sbjct: 229 RCTCGQGY 236 Score = 39.5 bits (88), Expect = 0.007 Identities = 23/74 (31%), Positives = 30/74 (40%), Gaps = 4/74 (5%) Frame = +2 Query: 203 ENVQNCFTCAPNLCLNNGVCQEALTEHGYVCLCAPGFGGN----NCDRIGESCRPGLCGP 370 ++ C +C NG C T GY C C G + C + E P C Sbjct: 550 KDADECLLFGQEIC-KNGFCLN--TRPGYECYCKQGTYYDPVKLQCFDMDECQDPSSCID 606 Query: 371 GKCMNTADSYKCAC 412 G+C+NT SY C C Sbjct: 607 GQCVNTEGSYNCFC 620 Score = 36.7 bits (81), Expect = 0.052 Identities = 22/66 (33%), Positives = 27/66 (40%), Gaps = 9/66 (13%) Frame = +2 Query: 242 CLNNGVCQEA----LTEHGYVCLCAPGF----GGNNCDRIGE-SCRPGLCGPGKCMNTAD 394 C+NN VC T + CLC GF G C + E G+CG C N Sbjct: 375 CVNNTVCDSHGFCDNTAGSFRCLCYQGFQAPQDGQGCVDVNECELLSGVCGEAFCENVEG 434 Query: 395 SYKCAC 412 S+ C C Sbjct: 435 SFLCVC 440 Score = 35.5 bits (78), Expect = 0.12 Identities = 26/86 (30%), Positives = 36/86 (41%), Gaps = 9/86 (10%) Frame = +2 Query: 209 VQNCFTCAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNN----CDRIGESCR-PGLCGPG 373 + C T P++C G C Y C+C G+ + C I E + LC G Sbjct: 1 INEC-TVNPDIC-GAGHCINLPVR--YTCICYEGYRFSEQQRKCVDIDECTQVQHLCSQG 56 Query: 374 KCMNTADSYKCACPVTY----TGKNC 439 +C NT S+ C CP + G NC Sbjct: 57 RCENTEGSFLCICPAGFMASEEGTNC 82 Score = 31.5 bits (68), Expect = 1.9 Identities = 22/73 (30%), Positives = 30/73 (41%), Gaps = 8/73 (10%) Frame = +2 Query: 242 CLNNGVCQEAL---TEHGYVC-LCAPGFG---GNNCDRIGESCRPGLCGPGKCMNTADSY 400 CL VC E T + C C G+ C+ I E P C +C+N+ SY Sbjct: 88 CLRPDVCGEGHCVNTVGAFRCEYCDSGYRMTQRGRCEDIDECLNPSTCPDEQCVNSPGSY 147 Query: 401 KCA-CPVTYTGKN 436 +C C + G N Sbjct: 148 QCVPCTEGFRGWN 160 >AC005254-1|AAC25581.1| 315|Homo sapiens PGCN_HUMAN, PARTIAL CDS protein. Length = 315 Score = 51.6 bits (118), Expect = 2e-06 Identities = 25/73 (34%), Positives = 34/73 (46%), Gaps = 1/73 (1%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLC-GPGKCMNTADSYK 403 C N CL+ G C T +G C C GF G NC+ + C C G C++ + + Sbjct: 6 CENNPCLHGGTCNANGTMYG--CSCDQGFAGENCEIDIDDCLCSPCENGGTCIDEVNGFV 63 Query: 404 CACPVTYTGKNCE 442 C C +Y G CE Sbjct: 64 CLCLPSYGGSFCE 76 Score = 44.0 bits (99), Expect = 3e-04 Identities = 19/51 (37%), Positives = 31/51 (60%) Frame = +2 Query: 206 NVQNCFTCAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPG 358 ++ +C C+P C N G C + + +G+VCLC P +GG+ C++ E C G Sbjct: 40 DIDDCL-CSP--CENGGTCIDEV--NGFVCLCLPSYGGSFCEKDTEGCDRG 85 >AB210004-1|BAE06086.1| 1335|Homo sapiens CSPG3 variant protein protein. Length = 1335 Score = 51.6 bits (118), Expect = 2e-06 Identities = 25/73 (34%), Positives = 34/73 (46%), Gaps = 1/73 (1%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLC-GPGKCMNTADSYK 403 C N CL+ G C T +G C C GF G NC+ + C C G C++ + + Sbjct: 1026 CENNPCLHGGTCNANGTMYG--CSCDQGFAGENCEIDIDDCLCSPCENGGTCIDEVNGFV 1083 Query: 404 CACPVTYTGKNCE 442 C C +Y G CE Sbjct: 1084 CLCLPSYGGSFCE 1096 Score = 44.0 bits (99), Expect = 3e-04 Identities = 19/51 (37%), Positives = 31/51 (60%) Frame = +2 Query: 206 NVQNCFTCAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPG 358 ++ +C C+P C N G C + + +G+VCLC P +GG+ C++ E C G Sbjct: 1060 DIDDCL-CSP--CENGGTCIDEV--NGFVCLCLPSYGGSFCEKDTEGCDRG 1105 >AB208801-1|BAD92038.1| 1348|Homo sapiens latent transforming growth factor beta binding protein 1 isoform LTBP-1S varian protein. Length = 1348 Score = 51.6 bits (118), Expect = 2e-06 Identities = 25/71 (35%), Positives = 39/71 (54%), Gaps = 4/71 (5%) Frame = +2 Query: 206 NVQNCFTCAPNLCLNNGVCQEALTEHGYVCLCAPGF----GGNNCDRIGESCRPGLCGPG 373 ++ C T +LC + G C+ TE ++C+C GF G NC + E RP +CG G Sbjct: 542 DIDEC-TQVQHLC-SQGRCEN--TEGSFLCICPAGFMASEEGTNCIDVDECLRPDVCGEG 597 Query: 374 KCMNTADSYKC 406 C+NT +++C Sbjct: 598 HCVNTVGAFRC 608 Score = 51.6 bits (118), Expect = 2e-06 Identities = 31/81 (38%), Positives = 38/81 (46%), Gaps = 12/81 (14%) Frame = +2 Query: 236 NLCLNN-GVCQEA---LTEHGYVCLCAPGF---GGNNCDRIGESCRPGLCGP-GKCMNTA 391 N CL + VCQ T Y C C GF C I E PGLCGP G+C+NT Sbjct: 790 NECLEDKSVCQRGDCINTAGSYDCTCPDGFQLDDNKTCQDINECEHPGLCGPQGECLNTE 849 Query: 392 DSYKCAC----PVTYTGKNCE 442 S+ C C ++ G+ CE Sbjct: 850 GSFHCVCQQGFSISADGRTCE 870 Score = 49.2 bits (112), Expect = 9e-06 Identities = 30/105 (28%), Positives = 47/105 (44%), Gaps = 8/105 (7%) Frame = +2 Query: 188 LALEKENVQNCFTCAPNLCLNNGVCQEALTEHGYVCLCAPGFG----GNNCDRIGESCRP 355 L+ K+ ++ C +G C+ TE + C+C G+ G++C+ I E Sbjct: 738 LSAAKDQCEDIDECQHRHLCAHGQCRN--TEGSFQCVCDQGYRASGLGDHCEDINECLED 795 Query: 356 -GLCGPGKCMNTADSYKCACPVTY---TGKNCEVKQLIEYPAFTG 478 +C G C+NTA SY C CP + K C+ E+P G Sbjct: 796 KSVCQRGDCINTAGSYDCTCPDGFQLDDNKTCQDINECEHPGLCG 840 Score = 46.4 bits (105), Expect = 6e-05 Identities = 27/77 (35%), Positives = 37/77 (48%), Gaps = 8/77 (10%) Frame = +2 Query: 236 NLCLNNGVCQEALTEHGYVCLCAPGF----GGNNCDRIGESCRPGLCGPGKCMNTADSYK 403 NLC+N G C+ TE + C C G+ + C+ I E LC G+C NT S++ Sbjct: 714 NLCVN-GQCKN--TEGSFRCTCGQGYQLSAAKDQCEDIDECQHRHLCAHGQCRNTEGSFQ 770 Query: 404 CACPVTY----TGKNCE 442 C C Y G +CE Sbjct: 771 CVCDQGYRASGLGDHCE 787 Score = 45.2 bits (102), Expect = 1e-04 Identities = 25/68 (36%), Positives = 32/68 (47%), Gaps = 6/68 (8%) Frame = +2 Query: 242 CLNNGVC--QEALTEHG-YVCL-CAPGFGGNN--CDRIGESCRPGLCGPGKCMNTADSYK 403 CLN C ++ + G Y C+ C GF G N C + E P +C G C N SY Sbjct: 629 CLNPSTCPDEQCVNSPGSYQCVPCTEGFRGWNGQCLDVDECLEPNVCANGDCSNLEGSYM 688 Query: 404 CACPVTYT 427 C+C YT Sbjct: 689 CSCHKGYT 696 Score = 44.0 bits (99), Expect = 3e-04 Identities = 21/60 (35%), Positives = 31/60 (51%), Gaps = 5/60 (8%) Frame = +2 Query: 260 CQEALTEHGY--VCLCAPGFGGNN---CDRIGESCRPGLCGPGKCMNTADSYKCACPVTY 424 C + + HGY + C PG+ N C I E G+C G+C+NT SY+C C + + Sbjct: 277 CPKKPSYHGYNQMMECLPGYKRVNNTFCQDINECQLQGVCPNGECLNTMGSYRCTCKIGF 336 Score = 43.2 bits (97), Expect = 6e-04 Identities = 24/68 (35%), Positives = 32/68 (47%), Gaps = 4/68 (5%) Frame = +2 Query: 233 PNLCLNNGVCQEALTEHGYVCLCAPGF----GGNNCDRIGESCRPGLCGPGKCMNTADSY 400 PN+C N G C E Y+C C G+ +C I E + LC G+C NT S+ Sbjct: 672 PNVCAN-GDCSNL--EGSYMCSCHKGYTRTPDHKHCRDIDECQQGNLCVNGQCKNTEGSF 728 Query: 401 KCACPVTY 424 +C C Y Sbjct: 729 RCTCGQGY 736 Score = 39.5 bits (88), Expect = 0.007 Identities = 23/74 (31%), Positives = 30/74 (40%), Gaps = 4/74 (5%) Frame = +2 Query: 203 ENVQNCFTCAPNLCLNNGVCQEALTEHGYVCLCAPGFGGN----NCDRIGESCRPGLCGP 370 ++ C +C NG C T GY C C G + C + E P C Sbjct: 1050 KDADECLLFGQEIC-KNGFCLN--TRPGYECYCKQGTYYDPVKLQCFDMDECQDPSSCID 1106 Query: 371 GKCMNTADSYKCAC 412 G+C+NT SY C C Sbjct: 1107 GQCVNTEGSYNCFC 1120 Score = 37.5 bits (83), Expect = 0.029 Identities = 23/64 (35%), Positives = 27/64 (42%), Gaps = 10/64 (15%) Frame = +2 Query: 251 NGVCQEALTEHGYVCLCAPGF----------GGNNCDRIGESCRPGLCGPGKCMNTADSY 400 NG C + GY C C G+ N CD + R LC KC+NT SY Sbjct: 1260 NGRCVRV--QEGYTCDCFDGYHLDTAKMTCVDVNECDELNN--RMSLCKNAKCINTDGSY 1315 Query: 401 KCAC 412 KC C Sbjct: 1316 KCLC 1319 Score = 36.7 bits (81), Expect = 0.052 Identities = 22/66 (33%), Positives = 27/66 (40%), Gaps = 9/66 (13%) Frame = +2 Query: 242 CLNNGVCQEA----LTEHGYVCLCAPGF----GGNNCDRIGE-SCRPGLCGPGKCMNTAD 394 C+NN VC T + CLC GF G C + E G+CG C N Sbjct: 875 CVNNTVCDSHGFCDNTAGSFRCLCYQGFQAPQDGQGCVDVNECELLSGVCGEAFCENVEG 934 Query: 395 SYKCAC 412 S+ C C Sbjct: 935 SFLCVC 940 Score = 35.5 bits (78), Expect = 0.12 Identities = 26/86 (30%), Positives = 36/86 (41%), Gaps = 9/86 (10%) Frame = +2 Query: 209 VQNCFTCAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNN----CDRIGESCR-PGLCGPG 373 + C T P++C G C Y C+C G+ + C I E + LC G Sbjct: 501 INEC-TVNPDIC-GAGHCINLPVR--YTCICYEGYRFSEQQRKCVDIDECTQVQHLCSQG 556 Query: 374 KCMNTADSYKCACPVTY----TGKNC 439 +C NT S+ C CP + G NC Sbjct: 557 RCENTEGSFLCICPAGFMASEEGTNC 582 Score = 31.5 bits (68), Expect = 1.9 Identities = 22/73 (30%), Positives = 30/73 (41%), Gaps = 8/73 (10%) Frame = +2 Query: 242 CLNNGVCQEAL---TEHGYVC-LCAPGFG---GNNCDRIGESCRPGLCGPGKCMNTADSY 400 CL VC E T + C C G+ C+ I E P C +C+N+ SY Sbjct: 588 CLRPDVCGEGHCVNTVGAFRCEYCDSGYRMTQRGRCEDIDECLNPSTCPDEQCVNSPGSY 647 Query: 401 KCA-CPVTYTGKN 436 +C C + G N Sbjct: 648 QCVPCTEGFRGWN 660 >U70313-1|AAC02649.1| 125|Homo sapiens integrin binding protein Del-1 protein. Length = 125 Score = 51.2 bits (117), Expect = 2e-06 Identities = 25/82 (30%), Positives = 36/82 (43%), Gaps = 10/82 (12%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGE--SCRPGLCGPGKCMNTADSY 400 C PN C N G+C L + + C C GF NC + E C P C G +++Y Sbjct: 26 CDPNPCENGGICLPGLADGSFSCECPDGFTDPNCSSVVEVGPCTPNPCHNGGTCEISEAY 85 Query: 401 K--------CACPVTYTGKNCE 442 + C CP + G +C+ Sbjct: 86 RGDTFIGYVCKCPRGFNGIHCQ 107 Score = 39.5 bits (88), Expect = 0.007 Identities = 22/54 (40%), Positives = 24/54 (44%), Gaps = 5/54 (9%) Frame = +2 Query: 227 CAPNLCLNNGVCQ--EAL---TEHGYVCLCAPGFGGNNCDRIGESCRPGLCGPG 373 C PN C N G C+ EA T GYVC C GF G +C C C G Sbjct: 68 CTPNPCHNGGTCEISEAYRGDTFIGYVCKCPRGFNGIHCQHNINECEVEPCKNG 121 >EF539882-1|ABS86974.1| 1547|Homo sapiens NRXN1-alpha protein. Length = 1547 Score = 51.2 bits (117), Expect = 2e-06 Identities = 34/117 (29%), Positives = 58/117 (49%), Gaps = 15/117 (12%) Frame = +2 Query: 29 SPDQWTVLELNQPLYIGGVPDFDQ---LPIDLAGA---SGFVGCISMLILGNEEKNIMAL 190 +P + +L+L+ LY+GG+P+ P ++ A G+VGCI L + + K+I + Sbjct: 640 APGESEILDLDDELYLGGLPENKAGLVFPTEVWTALLNYGYVGCIRDLFIDGQSKDIRQM 699 Query: 191 ALEKENV--------QNCFTCAPNLCLNNGVCQEALTEHGYVCLCA-PGFGGNNCDR 334 A + + C N C NNG+C++ YVC C+ G+ G +C+R Sbjct: 700 AEVQSTAGVKPSCSKETAKPCLSNPCKNNGMCRDGWNR--YVCDCSGTGYLGRSCER 754 Score = 40.3 bits (90), Expect = 0.004 Identities = 32/106 (30%), Positives = 49/106 (46%), Gaps = 9/106 (8%) Frame = +2 Query: 50 LELNQPLYIGGVPD--FDQLPIDLAGASGFVGCISMLILGNEEKNIMALAL--EKENVQN 217 L+L LYIGGV + LP + GF GC++ + L ++++ AL + + Sbjct: 1060 LDLKSDLYIGGVAKETYKSLPKLVHAKEGFQGCLASVDLNGRLPDLISDALFCNGQIERG 1119 Query: 218 C----FTCAPNLCLNNGVCQEALTEHGYVCLCA-PGFGGNNCDRIG 340 C TC + C N GVC + G+ C C+ F G C+ G Sbjct: 1120 CEGPSTTCQEDSCSNQGVCLQQW--DGFSCDCSMTSFSGPLCNDPG 1163 >BC150247-1|AAI50248.1| 1496|Homo sapiens NRXN1 protein protein. Length = 1496 Score = 51.2 bits (117), Expect = 2e-06 Identities = 34/117 (29%), Positives = 58/117 (49%), Gaps = 15/117 (12%) Frame = +2 Query: 29 SPDQWTVLELNQPLYIGGVPDFDQ---LPIDLAGA---SGFVGCISMLILGNEEKNIMAL 190 +P + +L+L+ LY+GG+P+ P ++ A G+VGCI L + + K+I + Sbjct: 592 APGESEILDLDDELYLGGLPENKAGLVFPTEVWTALLNYGYVGCIRDLFIDGQSKDIRQM 651 Query: 191 ALEKENV--------QNCFTCAPNLCLNNGVCQEALTEHGYVCLCA-PGFGGNNCDR 334 A + + C N C NNG+C++ YVC C+ G+ G +C+R Sbjct: 652 AEVQSTAGVKPSCSKETAKPCLSNPCKNNGMCRDGWNR--YVCDCSGTGYLGRSCER 706 Score = 40.3 bits (90), Expect = 0.004 Identities = 32/106 (30%), Positives = 49/106 (46%), Gaps = 9/106 (8%) Frame = +2 Query: 50 LELNQPLYIGGVPD--FDQLPIDLAGASGFVGCISMLILGNEEKNIMALAL--EKENVQN 217 L+L LYIGGV + LP + GF GC++ + L ++++ AL + + Sbjct: 1012 LDLKSDLYIGGVAKETYKSLPKLVHAKEGFQGCLASVDLNGRLPDLISDALFCNGQIERG 1071 Query: 218 C----FTCAPNLCLNNGVCQEALTEHGYVCLCA-PGFGGNNCDRIG 340 C TC + C N GVC + G+ C C+ F G C+ G Sbjct: 1072 CEGPSTTCQEDSCSNQGVCLQQW--DGFSCDCSMTSFSGPLCNDPG 1115 >BC110320-1|AAI10321.1| 383|Homo sapiens delta-like 2 homolog (Drosophila) protein. Length = 383 Score = 51.2 bits (117), Expect = 2e-06 Identities = 26/88 (29%), Positives = 35/88 (39%), Gaps = 1/88 (1%) Frame = +2 Query: 215 NCFTCAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLCGPG-KCMNTA 391 N C C N C + + + CLC GF G C + C C G +C + Sbjct: 174 NVDDCLMRPCANGATCLDGINR--FSCLCPEGFAGRFCTINLDDCASRPCQRGARCRDRV 231 Query: 392 DSYKCACPVTYTGKNCEVKQLIEYPAFT 475 + C CP Y GK CE+ + P T Sbjct: 232 HDFDCLCPSGYGGKTCELVLPVPDPPTT 259 Score = 43.6 bits (98), Expect = 4e-04 Identities = 29/84 (34%), Positives = 40/84 (47%), Gaps = 8/84 (9%) Frame = +2 Query: 218 CFTCAPNLCLNNGVCQEALTEHG--YVCLCAPGFGGNNCDRIGESCRP--GLC-GPGKCM 382 C T +P C N G C + + G Y C+C PGF G +C+R C C G+C Sbjct: 95 CTTQSP--CQNGGQC---MYDGGGEYHCVCLPGFHGRDCERKAGPCEQAGSPCRNGGQCQ 149 Query: 383 NT---ADSYKCACPVTYTGKNCEV 445 + A ++ C C V + G CEV Sbjct: 150 DDQGFALNFTCRCLVGFVGARCEV 173 Score = 40.3 bits (90), Expect = 0.004 Identities = 21/72 (29%), Positives = 31/72 (43%), Gaps = 3/72 (4%) Frame = +2 Query: 242 CLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESC-RPGLC-GPGKCM-NTADSYKCAC 412 C+ CQ + C+C G+ G CD+ C C G+CM + Y C C Sbjct: 60 CVRMPGCQHGTCHQPWQCICHSGWAGKFCDKDEHICTTQSPCQNGGQCMYDGGGEYHCVC 119 Query: 413 PVTYTGKNCEVK 448 + G++CE K Sbjct: 120 LPGFHGRDCERK 131 Score = 30.7 bits (66), Expect = 3.4 Identities = 17/50 (34%), Positives = 24/50 (48%) Frame = +2 Query: 293 CLCAPGFGGNNCDRIGESCRPGLCGPGKCMNTADSYKCACPVTYTGKNCE 442 C C PG+ G +C+R PG C G C ++C C + GK C+ Sbjct: 46 CRCDPGWEGLHCERCVR--MPG-CQHGTC---HQPWQCICHSGWAGKFCD 89 >AY358126-1|AAQ88493.1| 383|Homo sapiens PSGC2903 protein. Length = 383 Score = 51.2 bits (117), Expect = 2e-06 Identities = 26/88 (29%), Positives = 35/88 (39%), Gaps = 1/88 (1%) Frame = +2 Query: 215 NCFTCAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLCGPG-KCMNTA 391 N C C N C + + + CLC GF G C + C C G +C + Sbjct: 174 NVDDCLMRPCANGATCLDGINR--FSCLCPEGFAGRFCTINLDDCASRPCQRGARCRDRV 231 Query: 392 DSYKCACPVTYTGKNCEVKQLIEYPAFT 475 + C CP Y GK CE+ + P T Sbjct: 232 HDFDCLCPSGYGGKTCELVLPVPDPPTT 259 Score = 43.6 bits (98), Expect = 4e-04 Identities = 29/84 (34%), Positives = 40/84 (47%), Gaps = 8/84 (9%) Frame = +2 Query: 218 CFTCAPNLCLNNGVCQEALTEHG--YVCLCAPGFGGNNCDRIGESCRP--GLC-GPGKCM 382 C T +P C N G C + + G Y C+C PGF G +C+R C C G+C Sbjct: 95 CTTQSP--CQNGGQC---MYDGGGEYHCVCLPGFHGRDCERKAGPCEQAGSPCRNGGQCQ 149 Query: 383 NT---ADSYKCACPVTYTGKNCEV 445 + A ++ C C V + G CEV Sbjct: 150 DDQGFALNFTCRCLVGFVGARCEV 173 Score = 40.3 bits (90), Expect = 0.004 Identities = 21/72 (29%), Positives = 31/72 (43%), Gaps = 3/72 (4%) Frame = +2 Query: 242 CLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESC-RPGLC-GPGKCM-NTADSYKCAC 412 C+ CQ + C+C G+ G CD+ C C G+CM + Y C C Sbjct: 60 CVRMPGCQHGTCHQPWQCICHSGWAGKFCDKDEHICTTQSPCQNGGQCMYDGGGEYHCVC 119 Query: 413 PVTYTGKNCEVK 448 + G++CE K Sbjct: 120 LPGFHGRDCERK 131 Score = 30.7 bits (66), Expect = 3.4 Identities = 17/50 (34%), Positives = 24/50 (48%) Frame = +2 Query: 293 CLCAPGFGGNNCDRIGESCRPGLCGPGKCMNTADSYKCACPVTYTGKNCE 442 C C PG+ G +C+R PG C G C ++C C + GK C+ Sbjct: 46 CRCDPGWEGLHCERCVR--MPG-CQHGTC---HQPWQCICHSGWAGKFCD 89 >AL359813-9|CAI23224.1| 383|Homo sapiens EGF-like-domain, multiple 9 protein. Length = 383 Score = 51.2 bits (117), Expect = 2e-06 Identities = 26/88 (29%), Positives = 35/88 (39%), Gaps = 1/88 (1%) Frame = +2 Query: 215 NCFTCAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLCGPG-KCMNTA 391 N C C N C + + + CLC GF G C + C C G +C + Sbjct: 174 NVDDCLMRPCANGATCLDGINR--FSCLCPEGFAGRFCTINLDDCASRPCQRGARCRDRV 231 Query: 392 DSYKCACPVTYTGKNCEVKQLIEYPAFT 475 + C CP Y GK CE+ + P T Sbjct: 232 HDFDCLCPSGYGGKTCELVLPVPDPPTT 259 Score = 43.6 bits (98), Expect = 4e-04 Identities = 29/84 (34%), Positives = 40/84 (47%), Gaps = 8/84 (9%) Frame = +2 Query: 218 CFTCAPNLCLNNGVCQEALTEHG--YVCLCAPGFGGNNCDRIGESCRP--GLC-GPGKCM 382 C T +P C N G C + + G Y C+C PGF G +C+R C C G+C Sbjct: 95 CTTQSP--CQNGGQC---MYDGGGEYHCVCLPGFHGRDCERKAGPCEQAGSPCRNGGQCQ 149 Query: 383 NT---ADSYKCACPVTYTGKNCEV 445 + A ++ C C V + G CEV Sbjct: 150 DDQGFALNFTCRCLVGFVGARCEV 173 Score = 40.3 bits (90), Expect = 0.004 Identities = 21/72 (29%), Positives = 31/72 (43%), Gaps = 3/72 (4%) Frame = +2 Query: 242 CLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESC-RPGLC-GPGKCM-NTADSYKCAC 412 C+ CQ + C+C G+ G CD+ C C G+CM + Y C C Sbjct: 60 CVRMPGCQHGTCHQPWQCICHSGWAGKFCDKDEHICTTQSPCQNGGQCMYDGGGEYHCVC 119 Query: 413 PVTYTGKNCEVK 448 + G++CE K Sbjct: 120 LPGFHGRDCERK 131 Score = 30.7 bits (66), Expect = 3.4 Identities = 17/50 (34%), Positives = 24/50 (48%) Frame = +2 Query: 293 CLCAPGFGGNNCDRIGESCRPGLCGPGKCMNTADSYKCACPVTYTGKNCE 442 C C PG+ G +C+R PG C G C ++C C + GK C+ Sbjct: 46 CRCDPGWEGLHCERCVR--MPG-CQHGTC---HQPWQCICHSGWAGKFCD 89 >AL359813-8|CAI23223.1| 377|Homo sapiens EGF-like-domain, multiple 9 protein. Length = 377 Score = 51.2 bits (117), Expect = 2e-06 Identities = 26/88 (29%), Positives = 35/88 (39%), Gaps = 1/88 (1%) Frame = +2 Query: 215 NCFTCAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLCGPG-KCMNTA 391 N C C N C + + + CLC GF G C + C C G +C + Sbjct: 168 NVDDCLMRPCANGATCLDGINR--FSCLCPEGFAGRFCTINLDDCASRPCQRGARCRDRV 225 Query: 392 DSYKCACPVTYTGKNCEVKQLIEYPAFT 475 + C CP Y GK CE+ + P T Sbjct: 226 HDFDCLCPSGYGGKTCELVLPVPDPPTT 253 Score = 43.6 bits (98), Expect = 4e-04 Identities = 29/84 (34%), Positives = 40/84 (47%), Gaps = 8/84 (9%) Frame = +2 Query: 218 CFTCAPNLCLNNGVCQEALTEHG--YVCLCAPGFGGNNCDRIGESCRP--GLC-GPGKCM 382 C T +P C N G C + + G Y C+C PGF G +C+R C C G+C Sbjct: 89 CTTQSP--CQNGGQC---MYDGGGEYHCVCLPGFHGRDCERKAGPCEQAGSPCRNGGQCQ 143 Query: 383 NT---ADSYKCACPVTYTGKNCEV 445 + A ++ C C V + G CEV Sbjct: 144 DDQGFALNFTCRCLVGFVGARCEV 167 Score = 34.7 bits (76), Expect = 0.21 Identities = 18/70 (25%), Positives = 29/70 (41%), Gaps = 1/70 (1%) Frame = +2 Query: 242 CLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLCGPGKCM-NTADSYKCACPV 418 C+ CQ + C+C G+ + C+ G G+CM + Y C C Sbjct: 60 CVRMPGCQHGTCHQPWQCICHSGWADEHICTTQSPCQNG----GQCMYDGGGEYHCVCLP 115 Query: 419 TYTGKNCEVK 448 + G++CE K Sbjct: 116 GFHGRDCERK 125 >AL359813-6|CAI23221.1| 288|Homo sapiens EGF-like-domain, multiple 9 protein. Length = 288 Score = 51.2 bits (117), Expect = 2e-06 Identities = 26/88 (29%), Positives = 35/88 (39%), Gaps = 1/88 (1%) Frame = +2 Query: 215 NCFTCAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDRIGESCRPGLCGPG-KCMNTA 391 N C C N C + + + CLC GF G C + C C G +C + Sbjct: 79 NVDDCLMRPCANGATCLDGINR--FSCLCPEGFAGRFCTINLDDCASRPCQRGARCRDRV 136 Query: 392 DSYKCACPVTYTGKNCEVKQLIEYPAFT 475 + C CP Y GK CE+ + P T Sbjct: 137 HDFDCLCPSGYGGKTCELVLPVPDPPTT 164 Score = 33.1 bits (72), Expect = 0.63 Identities = 22/77 (28%), Positives = 32/77 (41%), Gaps = 15/77 (19%) Frame = +2 Query: 260 CQEALTEHGYVCLCAPGFGGNNCDR--IGESC--RPGLC--------GPGKCMNT---AD 394 CQ + C+C G+ G CD+ G C + G C G+C + A Sbjct: 2 CQHGTCHQPWQCICHSGWAGKFCDKGFHGRDCERKAGPCEQAGSPCRNGGQCQDDQGFAL 61 Query: 395 SYKCACPVTYTGKNCEV 445 ++ C C V + G CEV Sbjct: 62 NFTCRCLVGFVGARCEV 78 >AK074396-1|BAB85069.1| 220|Homo sapiens protein ( Homo sapiens cDNA FLJ23816 fis, clone HSI02685. ). Length = 220 Score = 51.2 bits (117), Expect = 2e-06 Identities = 30/72 (41%), Positives = 35/72 (48%), Gaps = 11/72 (15%) Frame = +2 Query: 242 CLNNGVCQEAL--TEHGYVCLCAPGF----GGNNCDRIGESCRPGL-CGPGK-CMNTADS 397 C +CQ A TE Y CLC G+ G NC I E + CGPG+ C NT S Sbjct: 28 CRVRNLCQHACRNTEGSYQCLCPAGYRLLPSGKNCQDINECEEESIECGPGQMCFNTRGS 87 Query: 398 YKCA---CPVTY 424 Y+C CP TY Sbjct: 88 YQCVDTPCPATY 99 Score = 38.3 bits (85), Expect = 0.017 Identities = 22/54 (40%), Positives = 26/54 (48%), Gaps = 6/54 (11%) Frame = +2 Query: 299 CAPGFGGNN--CDRIGESCRPGLCGPGKCMNTADSYKCACPVTY----TGKNCE 442 C PGF N C + E LC C NT SY+C CP Y +GKNC+ Sbjct: 11 CPPGFIRQNGVCTDLDECRVRNLCQHA-CRNTEGSYQCLCPAGYRLLPSGKNCQ 63 >AC007462-1|AAF03536.1| 681|Homo sapiens unknown protein. Length = 681 Score = 51.2 bits (117), Expect = 2e-06 Identities = 34/117 (29%), Positives = 58/117 (49%), Gaps = 15/117 (12%) Frame = +2 Query: 29 SPDQWTVLELNQPLYIGGVPDFDQ---LPIDLAGA---SGFVGCISMLILGNEEKNIMAL 190 +P + +L+L+ LY+GG+P+ P ++ A G+VGCI L + + K+I + Sbjct: 160 APGESEILDLDDELYLGGLPENKAGLVFPTEVWTALLNYGYVGCIRDLFIDGQSKDIRQM 219 Query: 191 ALEKENV--------QNCFTCAPNLCLNNGVCQEALTEHGYVCLCA-PGFGGNNCDR 334 A + + C N C NNG+C++ YVC C+ G+ G +C+R Sbjct: 220 AEVQSTAGVKPSCSKETAKPCLSNPCKNNGMCRDGWNR--YVCDCSGTGYLGRSCER 274 Score = 39.9 bits (89), Expect = 0.006 Identities = 31/103 (30%), Positives = 48/103 (46%), Gaps = 9/103 (8%) Frame = +2 Query: 50 LELNQPLYIGGVPD--FDQLPIDLAGASGFVGCISMLILGNEEKNIMALAL--EKENVQN 217 L+L LYIGGV + LP + GF GC++ + L ++++ AL + + Sbjct: 580 LDLKSDLYIGGVAKETYKSLPKLVHAKEGFQGCLASVDLNGRLPDLISDALFCNGQIERG 639 Query: 218 C----FTCAPNLCLNNGVCQEALTEHGYVCLCA-PGFGGNNCD 331 C TC + C N GVC + G+ C C+ F G C+ Sbjct: 640 CEGPSTTCQEDSCSNQGVCLQQW--DGFSCDCSMTSFSGPLCN 680 >AB035356-1|BAA87821.1| 1477|Homo sapiens neurexin I-alpha protein protein. Length = 1477 Score = 51.2 bits (117), Expect = 2e-06 Identities = 34/117 (29%), Positives = 58/117 (49%), Gaps = 15/117 (12%) Frame = +2 Query: 29 SPDQWTVLELNQPLYIGGVPDFDQ---LPIDLAGA---SGFVGCISMLILGNEEKNIMAL 190 +P + +L+L+ LY+GG+P+ P ++ A G+VGCI L + + K+I + Sbjct: 600 APGESEILDLDDELYLGGLPENKAGLVFPTEVWTALLNYGYVGCIRDLFIDGQSKDIRQM 659 Query: 191 ALEKENV--------QNCFTCAPNLCLNNGVCQEALTEHGYVCLCA-PGFGGNNCDR 334 A + + C N C NNG+C++ YVC C+ G+ G +C+R Sbjct: 660 AEVQSTAGVKPSCSKETAKPCLSNPCKNNGMCRDGWNR--YVCDCSGTGYLGRSCER 714 Score = 40.3 bits (90), Expect = 0.004 Identities = 32/106 (30%), Positives = 49/106 (46%), Gaps = 9/106 (8%) Frame = +2 Query: 50 LELNQPLYIGGVPD--FDQLPIDLAGASGFVGCISMLILGNEEKNIMALAL--EKENVQN 217 L+L LYIGGV + LP + GF GC++ + L ++++ AL + + Sbjct: 1020 LDLKSDLYIGGVAKETYKSLPKLVHAKEGFQGCLASVDLNGRLPDLISDALFCNGQIERG 1079 Query: 218 C----FTCAPNLCLNNGVCQEALTEHGYVCLCA-PGFGGNNCDRIG 340 C TC + C N GVC + G+ C C+ F G C+ G Sbjct: 1080 CEGPSTTCQEDSCSNQGVCLQQW--DGFSCDCSMTSFSGPLCNDPG 1123 >AB011150-1|BAA25504.2| 1542|Homo sapiens KIAA0578 protein protein. Length = 1542 Score = 51.2 bits (117), Expect = 2e-06 Identities = 34/117 (29%), Positives = 58/117 (49%), Gaps = 15/117 (12%) Frame = +2 Query: 29 SPDQWTVLELNQPLYIGGVPDFDQ---LPIDLAGA---SGFVGCISMLILGNEEKNIMAL 190 +P + +L+L+ LY+GG+P+ P ++ A G+VGCI L + + K+I + Sbjct: 638 APGESEILDLDDELYLGGLPENKAGLVFPTEVWTALLNYGYVGCIRDLFIDGQSKDIRQM 697 Query: 191 ALEKENV--------QNCFTCAPNLCLNNGVCQEALTEHGYVCLCA-PGFGGNNCDR 334 A + + C N C NNG+C++ YVC C+ G+ G +C+R Sbjct: 698 AEVQSTAGVKPSCSKETAKPCLSNPCKNNGMCRDGWNR--YVCDCSGTGYLGRSCER 752 Score = 40.3 bits (90), Expect = 0.004 Identities = 32/106 (30%), Positives = 49/106 (46%), Gaps = 9/106 (8%) Frame = +2 Query: 50 LELNQPLYIGGVPD--FDQLPIDLAGASGFVGCISMLILGNEEKNIMALAL--EKENVQN 217 L+L LYIGGV + LP + GF GC++ + L ++++ AL + + Sbjct: 1058 LDLKSDLYIGGVAKETYKSLPKLVHAKEGFQGCLASVDLNGRLPDLISDALFCNGQIERG 1117 Query: 218 C----FTCAPNLCLNNGVCQEALTEHGYVCLCA-PGFGGNNCDRIG 340 C TC + C N GVC + G+ C C+ F G C+ G Sbjct: 1118 CEGPSTTCQEDSCSNQGVCLQQW--DGFSCDCSMTSFSGPLCNDPG 1161 >Z37976-1|CAA86030.1| 1821|Homo sapiens LTBP-2 precursor protein. Length = 1821 Score = 50.8 bits (116), Expect = 3e-06 Identities = 26/67 (38%), Positives = 32/67 (47%), Gaps = 8/67 (11%) Frame = +2 Query: 236 NLCLNNGVCQ---EALTEHG-YVCLCAPGF----GGNNCDRIGESCRPGLCGPGKCMNTA 391 N C+ C E L HG + CLCAPGF GG +C + E C G C+NT Sbjct: 1178 NECMGEEHCAPHGECLNSHGSFFCLCAPGFVSAEGGTSCQDVDECATTDPCVGGHCVNTE 1237 Query: 392 DSYKCAC 412 S+ C C Sbjct: 1238 GSFNCLC 1244 Score = 48.4 bits (110), Expect = 2e-05 Identities = 28/73 (38%), Positives = 34/73 (46%), Gaps = 4/73 (5%) Frame = +2 Query: 206 NVQNCFTCAPNLCLNNGVCQEALTEHGYVCLCAPGF----GGNNCDRIGESCRPGLCGPG 373 + C P LC NG C T GYVCLC PGF C+ E C+ C G Sbjct: 1485 DADECVIFGPGLC-PNGRCLN--TVPGYVCLCNPGFHYDASHKKCEDHDE-CQDLACENG 1540 Query: 374 KCMNTADSYKCAC 412 +C+NT S+ C C Sbjct: 1541 ECVNTEGSFHCFC 1553 Score = 47.2 bits (107), Expect = 4e-05 Identities = 28/74 (37%), Positives = 35/74 (47%), Gaps = 7/74 (9%) Frame = +2 Query: 236 NLCLNNGVC---QEALTEHGYVCLCAPGF---GGNNCDRIGESCRPGLCGPGKCMNTADS 397 N C GVC Q TE Y C C G+ +C I E PG C G+C+N+ S Sbjct: 932 NECEQPGVCSGGQCTNTEGSYHCECDQGYIMVRKGHCQDINECRHPGTCPDGRCVNSPGS 991 Query: 398 YKC-ACPVTYTGKN 436 Y C AC Y G++ Sbjct: 992 YTCLACEEGYRGQS 1005 Score = 46.4 bits (105), Expect = 6e-05 Identities = 24/72 (33%), Positives = 30/72 (41%), Gaps = 6/72 (8%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGF------GGNNCDRIGESCRPGLCGPGKCMNT 388 C + C G C + Y C C PG+ C I E +PG+C G+C NT Sbjct: 891 CLRDPCQGKGRCINRVGS--YSCFCYPGYTLATSGATQECQDINECEQPGVCSGGQCTNT 948 Query: 389 ADSYKCACPVTY 424 SY C C Y Sbjct: 949 EGSYHCECDQGY 960 Score = 46.4 bits (105), Expect = 6e-05 Identities = 23/69 (33%), Positives = 33/69 (47%), Gaps = 6/69 (8%) Frame = +2 Query: 236 NLCLNNGVCQEALTEHG---YVCL-CAPGFGGNN--CDRIGESCRPGLCGPGKCMNTADS 397 N C + G C + + Y CL C G+ G + C + E PG+C GKC N S Sbjct: 972 NECRHPGTCPDGRCVNSPGSYTCLACEEGYRGQSGSCVDVNECLTPGVCAHGKCTNLEGS 1031 Query: 398 YKCACPVTY 424 ++C+C Y Sbjct: 1032 FRCSCEQGY 1040 Score = 44.0 bits (99), Expect = 3e-04 Identities = 26/84 (30%), Positives = 34/84 (40%), Gaps = 4/84 (4%) Frame = +2 Query: 188 LALEKENVQNCFTCAPNLCLNNGVCQEALTEHGYVCLCAPGF----GGNNCDRIGESCRP 355 + L + C A N+C G C GY C+C+PG+ C E R Sbjct: 838 VTLSTPGIDRCAAGATNVC-GPGTCVNL--PDGYRCVCSPGYQLHPSQAYCTDDNECLRD 894 Query: 356 GLCGPGKCMNTADSYKCACPVTYT 427 G G+C+N SY C C YT Sbjct: 895 PCQGKGRCINRVGSYSCFCYPGYT 918 Score = 41.9 bits (94), Expect = 0.001 Identities = 23/75 (30%), Positives = 34/75 (45%), Gaps = 5/75 (6%) Frame = +2 Query: 197 EKENVQNCFTCAPNLCLNNGVCQEALTEHGYVC-LCAPGF----GGNNCDRIGESCRPGL 361 +++ Q+ CA G+C TE + C C G+ G C+ + E PG+ Sbjct: 1045 DEKGCQDVDECASRASCPTGLCLN--TEGSFACSACENGYWVNEDGTACEDLDECAFPGV 1102 Query: 362 CGPGKCMNTADSYKC 406 C G C NTA S+ C Sbjct: 1103 CPSGVCTNTAGSFSC 1117 Score = 36.7 bits (81), Expect = 0.052 Identities = 25/70 (35%), Positives = 35/70 (50%), Gaps = 7/70 (10%) Frame = +2 Query: 227 CA-PNLCLNNGVCQEALTEHGYVCL-CAPGFG----GNNCDRIGESCRP-GLCGPGKCMN 385 CA P +C +GVC T + C C G+ G++C+ + E P C G+C N Sbjct: 1097 CAFPGVC-PSGVCTN--TAGSFSCKDCDGGYRPSPLGDSCEDVDECEDPQSSCLGGECKN 1153 Query: 386 TADSYKCACP 415 T SY+C CP Sbjct: 1154 TVGSYQCLCP 1163 Score = 34.7 bits (76), Expect = 0.21 Identities = 22/71 (30%), Positives = 27/71 (38%), Gaps = 8/71 (11%) Frame = +2 Query: 236 NLCLNNGVCQEALT---EHGYVCLCAPGF----GGNNCDRIGESCRPGLCGPGKCMNTAD 394 N CL GVC E + C C G+ C + E C G C+NT Sbjct: 1012 NECLTPGVCAHGKCTNLEGSFRCSCEQGYEVTSDEKGCQDVDECASRASCPTGLCLNTEG 1071 Query: 395 SYKC-ACPVTY 424 S+ C AC Y Sbjct: 1072 SFACSACENGY 1082 Score = 34.3 bits (75), Expect = 0.27 Identities = 21/68 (30%), Positives = 31/68 (45%), Gaps = 6/68 (8%) Frame = +2 Query: 227 CAPN-LCLNNGVCQEALTEHGYVCLCAPGF----GGNNCDRIGE-SCRPGLCGPGKCMNT 388 CA + +C ++G C T+ + CLC GF G +C + E +CG C N Sbjct: 1307 CANDTMCGSHGFCDN--TDGSFRCLCDQGFEISPSGWDCVDVNECELMLAVCGAALCENV 1364 Query: 389 ADSYKCAC 412 S+ C C Sbjct: 1365 EGSFLCLC 1372 Score = 33.9 bits (74), Expect = 0.36 Identities = 13/30 (43%), Positives = 16/30 (53%) Frame = +2 Query: 323 NCDRIGESCRPGLCGPGKCMNTADSYKCAC 412 +C I E GLC +C+NT SY C C Sbjct: 619 HCQDINECLTLGLCKDAECVNTRGSYLCTC 648 Score = 33.9 bits (74), Expect = 0.36 Identities = 26/74 (35%), Positives = 33/74 (44%), Gaps = 6/74 (8%) Frame = +2 Query: 203 ENVQNCFTCAPNLCLNNGVCQEALTEHGYVCLCAPGFG----GNNCDRIGESCRPG--LC 364 ++V C T P C+ G C TE + CLC GF C I E G +C Sbjct: 1217 QDVDECATTDP--CVG-GHCVN--TEGSFNCLCETGFQPSPESGECVDIDECEDYGDPVC 1271 Query: 365 GPGKCMNTADSYKC 406 G KC N+ SY+C Sbjct: 1272 GTWKCENSPGSYRC 1285 Score = 31.5 bits (68), Expect = 1.9 Identities = 23/71 (32%), Positives = 26/71 (36%), Gaps = 10/71 (14%) Frame = +2 Query: 251 NGVCQEALTEHGYVCLCAPGF----------GGNNCDRIGESCRPGLCGPGKCMNTADSY 400 NG C GY C C GF N CD + LC G C NT SY Sbjct: 1745 NGRCVRV--REGYTCDCFEGFQLDAAHMACVDVNECDDLNGPAV--LCVHGYCENTEGSY 1800 Query: 401 KCACPVTYTGK 433 +C C Y + Sbjct: 1801 RCHCSPGYVAE 1811 >S82451-1|AAB37459.1| 1821|Homo sapiens latent transforming growth factor-beta-binding protein-2 protein. Length = 1821 Score = 50.8 bits (116), Expect = 3e-06 Identities = 26/67 (38%), Positives = 32/67 (47%), Gaps = 8/67 (11%) Frame = +2 Query: 236 NLCLNNGVCQ---EALTEHG-YVCLCAPGF----GGNNCDRIGESCRPGLCGPGKCMNTA 391 N C+ C E L HG + CLCAPGF GG +C + E C G C+NT Sbjct: 1178 NECMGEEHCAPHGECLNSHGSFFCLCAPGFVSAEGGTSCQDVDECATTDPCVGGHCVNTE 1237 Query: 392 DSYKCAC 412 S+ C C Sbjct: 1238 GSFNCLC 1244 Score = 48.4 bits (110), Expect = 2e-05 Identities = 28/73 (38%), Positives = 34/73 (46%), Gaps = 4/73 (5%) Frame = +2 Query: 206 NVQNCFTCAPNLCLNNGVCQEALTEHGYVCLCAPGF----GGNNCDRIGESCRPGLCGPG 373 + C P LC NG C T GYVCLC PGF C+ E C+ C G Sbjct: 1485 DADECVIFGPGLC-PNGRCLN--TVPGYVCLCNPGFHYDASHKKCEDHDE-CQDLACENG 1540 Query: 374 KCMNTADSYKCAC 412 +C+NT S+ C C Sbjct: 1541 ECVNTEGSFHCFC 1553 Score = 47.2 bits (107), Expect = 4e-05 Identities = 28/74 (37%), Positives = 35/74 (47%), Gaps = 7/74 (9%) Frame = +2 Query: 236 NLCLNNGVC---QEALTEHGYVCLCAPGF---GGNNCDRIGESCRPGLCGPGKCMNTADS 397 N C GVC Q TE Y C C G+ +C I E PG C G+C+N+ S Sbjct: 932 NECEQPGVCSGGQCTNTEGSYHCECDQGYIMVRKGHCQDINECRHPGTCPDGRCVNSPGS 991 Query: 398 YKC-ACPVTYTGKN 436 Y C AC Y G++ Sbjct: 992 YTCLACEEGYRGQS 1005 Score = 46.4 bits (105), Expect = 6e-05 Identities = 24/72 (33%), Positives = 30/72 (41%), Gaps = 6/72 (8%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGF------GGNNCDRIGESCRPGLCGPGKCMNT 388 C + C G C + Y C C PG+ C I E +PG+C G+C NT Sbjct: 891 CLRDPCKGKGRCINRVGS--YSCFCYPGYTLATSGATQECQDINECEQPGVCSGGQCTNT 948 Query: 389 ADSYKCACPVTY 424 SY C C Y Sbjct: 949 EGSYHCECDQGY 960 Score = 46.4 bits (105), Expect = 6e-05 Identities = 23/69 (33%), Positives = 33/69 (47%), Gaps = 6/69 (8%) Frame = +2 Query: 236 NLCLNNGVCQEALTEHG---YVCL-CAPGFGGNN--CDRIGESCRPGLCGPGKCMNTADS 397 N C + G C + + Y CL C G+ G + C + E PG+C GKC N S Sbjct: 972 NECRHPGTCPDGRCVNSPGSYTCLACEEGYRGQSGSCVDVNECLTPGVCAHGKCTNLEGS 1031 Query: 398 YKCACPVTY 424 ++C+C Y Sbjct: 1032 FRCSCEQGY 1040 Score = 44.0 bits (99), Expect = 3e-04 Identities = 26/84 (30%), Positives = 34/84 (40%), Gaps = 4/84 (4%) Frame = +2 Query: 188 LALEKENVQNCFTCAPNLCLNNGVCQEALTEHGYVCLCAPGF----GGNNCDRIGESCRP 355 + L + C A N+C G C GY C+C+PG+ C E R Sbjct: 838 VTLSTPGIDRCAAGATNVC-GPGTCVNL--PDGYRCVCSPGYQLHPSQAYCTDDNECLRD 894 Query: 356 GLCGPGKCMNTADSYKCACPVTYT 427 G G+C+N SY C C YT Sbjct: 895 PCKGKGRCINRVGSYSCFCYPGYT 918 Score = 41.9 bits (94), Expect = 0.001 Identities = 23/75 (30%), Positives = 34/75 (45%), Gaps = 5/75 (6%) Frame = +2 Query: 197 EKENVQNCFTCAPNLCLNNGVCQEALTEHGYVC-LCAPGF----GGNNCDRIGESCRPGL 361 +++ Q+ CA G+C TE + C C G+ G C+ + E PG+ Sbjct: 1045 DEKGCQDVDECASRASCPTGLCLN--TEGSFACSACENGYWVNEDGTACEDLDECAFPGV 1102 Query: 362 CGPGKCMNTADSYKC 406 C G C NTA S+ C Sbjct: 1103 CPSGVCTNTAGSFSC 1117 Score = 36.7 bits (81), Expect = 0.052 Identities = 25/70 (35%), Positives = 35/70 (50%), Gaps = 7/70 (10%) Frame = +2 Query: 227 CA-PNLCLNNGVCQEALTEHGYVCL-CAPGFG----GNNCDRIGESCRP-GLCGPGKCMN 385 CA P +C +GVC T + C C G+ G++C+ + E P C G+C N Sbjct: 1097 CAFPGVC-PSGVCTN--TAGSFSCKDCDGGYRPSPLGDSCEDVDECEDPQSSCLGGECKN 1153 Query: 386 TADSYKCACP 415 T SY+C CP Sbjct: 1154 TVGSYQCLCP 1163 Score = 34.7 bits (76), Expect = 0.21 Identities = 22/71 (30%), Positives = 27/71 (38%), Gaps = 8/71 (11%) Frame = +2 Query: 236 NLCLNNGVCQEALT---EHGYVCLCAPGF----GGNNCDRIGESCRPGLCGPGKCMNTAD 394 N CL GVC E + C C G+ C + E C G C+NT Sbjct: 1012 NECLTPGVCAHGKCTNLEGSFRCSCEQGYEVTSDEKGCQDVDECASRASCPTGLCLNTEG 1071 Query: 395 SYKC-ACPVTY 424 S+ C AC Y Sbjct: 1072 SFACSACENGY 1082 Score = 34.3 bits (75), Expect = 0.27 Identities = 21/68 (30%), Positives = 31/68 (45%), Gaps = 6/68 (8%) Frame = +2 Query: 227 CAPN-LCLNNGVCQEALTEHGYVCLCAPGF----GGNNCDRIGE-SCRPGLCGPGKCMNT 388 CA + +C ++G C T+ + CLC GF G +C + E +CG C N Sbjct: 1307 CANDTMCGSHGFCDN--TDGSFRCLCDQGFEISPSGWDCVDVNECELMLAVCGAALCENV 1364 Query: 389 ADSYKCAC 412 S+ C C Sbjct: 1365 EGSFLCLC 1372 Score = 33.9 bits (74), Expect = 0.36 Identities = 13/30 (43%), Positives = 16/30 (53%) Frame = +2 Query: 323 NCDRIGESCRPGLCGPGKCMNTADSYKCAC 412 +C I E GLC +C+NT SY C C Sbjct: 619 HCQDINECLTLGLCKDAECVNTRGSYLCTC 648 Score = 33.9 bits (74), Expect = 0.36 Identities = 26/74 (35%), Positives = 33/74 (44%), Gaps = 6/74 (8%) Frame = +2 Query: 203 ENVQNCFTCAPNLCLNNGVCQEALTEHGYVCLCAPGFG----GNNCDRIGESCRPG--LC 364 ++V C T P C+ G C TE + CLC GF C I E G +C Sbjct: 1217 QDVDECATTDP--CVG-GHCVN--TEGSFNCLCETGFQPSPESGECVDIDECEDYGDPVC 1271 Query: 365 GPGKCMNTADSYKC 406 G KC N+ SY+C Sbjct: 1272 GTWKCENSPGSYRC 1285 Score = 31.5 bits (68), Expect = 1.9 Identities = 23/71 (32%), Positives = 26/71 (36%), Gaps = 10/71 (14%) Frame = +2 Query: 251 NGVCQEALTEHGYVCLCAPGF----------GGNNCDRIGESCRPGLCGPGKCMNTADSY 400 NG C GY C C GF N CD + LC G C NT SY Sbjct: 1745 NGRCVRV--REGYTCDCFEGFQLDAAHMACVDVNECDDLNGPAV--LCVHGYCENTEGSY 1800 Query: 401 KCACPVTYTGK 433 +C C Y + Sbjct: 1801 RCHCSPGYVAE 1811 >BC078659-1|AAH78659.1| 1821|Homo sapiens latent transforming growth factor beta binding protein 2 protein. Length = 1821 Score = 50.8 bits (116), Expect = 3e-06 Identities = 26/67 (38%), Positives = 32/67 (47%), Gaps = 8/67 (11%) Frame = +2 Query: 236 NLCLNNGVCQ---EALTEHG-YVCLCAPGF----GGNNCDRIGESCRPGLCGPGKCMNTA 391 N C+ C E L HG + CLCAPGF GG +C + E C G C+NT Sbjct: 1178 NECMGEEHCAPHGECLNSHGSFFCLCAPGFVSAEGGTSCQDVDECATTDPCVGGHCVNTE 1237 Query: 392 DSYKCAC 412 S+ C C Sbjct: 1238 GSFNCLC 1244 Score = 48.4 bits (110), Expect = 2e-05 Identities = 28/73 (38%), Positives = 34/73 (46%), Gaps = 4/73 (5%) Frame = +2 Query: 206 NVQNCFTCAPNLCLNNGVCQEALTEHGYVCLCAPGF----GGNNCDRIGESCRPGLCGPG 373 + C P LC NG C T GYVCLC PGF C+ E C+ C G Sbjct: 1485 DADECVIFGPGLC-PNGRCLN--TVPGYVCLCNPGFHYDASHKKCEDHDE-CQDLACENG 1540 Query: 374 KCMNTADSYKCAC 412 +C+NT S+ C C Sbjct: 1541 ECVNTEGSFHCFC 1553 Score = 47.2 bits (107), Expect = 4e-05 Identities = 28/74 (37%), Positives = 35/74 (47%), Gaps = 7/74 (9%) Frame = +2 Query: 236 NLCLNNGVC---QEALTEHGYVCLCAPGF---GGNNCDRIGESCRPGLCGPGKCMNTADS 397 N C GVC Q TE Y C C G+ +C I E PG C G+C+N+ S Sbjct: 932 NECEQPGVCSGGQCTNTEGSYHCECDQGYIMVRKGHCQDINECRHPGTCPDGRCVNSPGS 991 Query: 398 YKC-ACPVTYTGKN 436 Y C AC Y G++ Sbjct: 992 YTCLACEEGYRGQS 1005 Score = 46.4 bits (105), Expect = 6e-05 Identities = 24/72 (33%), Positives = 30/72 (41%), Gaps = 6/72 (8%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGF------GGNNCDRIGESCRPGLCGPGKCMNT 388 C + C G C + Y C C PG+ C I E +PG+C G+C NT Sbjct: 891 CLRDPCKGKGRCINRVGS--YSCFCYPGYTLATSGATQECQDINECEQPGVCSGGQCTNT 948 Query: 389 ADSYKCACPVTY 424 SY C C Y Sbjct: 949 EGSYHCECDQGY 960 Score = 46.4 bits (105), Expect = 6e-05 Identities = 23/69 (33%), Positives = 33/69 (47%), Gaps = 6/69 (8%) Frame = +2 Query: 236 NLCLNNGVCQEALTEHG---YVCL-CAPGFGGNN--CDRIGESCRPGLCGPGKCMNTADS 397 N C + G C + + Y CL C G+ G + C + E PG+C GKC N S Sbjct: 972 NECRHPGTCPDGRCVNSPGSYTCLACEEGYRGQSGSCVDVNECLTPGVCAHGKCTNLEGS 1031 Query: 398 YKCACPVTY 424 ++C+C Y Sbjct: 1032 FRCSCEQGY 1040 Score = 44.0 bits (99), Expect = 3e-04 Identities = 26/84 (30%), Positives = 34/84 (40%), Gaps = 4/84 (4%) Frame = +2 Query: 188 LALEKENVQNCFTCAPNLCLNNGVCQEALTEHGYVCLCAPGF----GGNNCDRIGESCRP 355 + L + C A N+C G C GY C+C+PG+ C E R Sbjct: 838 VTLSTPGIDRCAAGATNVC-GPGTCVNL--PDGYRCVCSPGYQLHPSQAYCTDDNECLRD 894 Query: 356 GLCGPGKCMNTADSYKCACPVTYT 427 G G+C+N SY C C YT Sbjct: 895 PCKGKGRCINRVGSYSCFCYPGYT 918 Score = 41.9 bits (94), Expect = 0.001 Identities = 23/75 (30%), Positives = 34/75 (45%), Gaps = 5/75 (6%) Frame = +2 Query: 197 EKENVQNCFTCAPNLCLNNGVCQEALTEHGYVC-LCAPGF----GGNNCDRIGESCRPGL 361 +++ Q+ CA G+C TE + C C G+ G C+ + E PG+ Sbjct: 1045 DEKGCQDVDECASRASCPTGLCLN--TEGSFACSACENGYWVNEDGTACEDLDECAFPGV 1102 Query: 362 CGPGKCMNTADSYKC 406 C G C NTA S+ C Sbjct: 1103 CPSGVCTNTAGSFSC 1117 Score = 36.7 bits (81), Expect = 0.052 Identities = 25/70 (35%), Positives = 35/70 (50%), Gaps = 7/70 (10%) Frame = +2 Query: 227 CA-PNLCLNNGVCQEALTEHGYVCL-CAPGFG----GNNCDRIGESCRP-GLCGPGKCMN 385 CA P +C +GVC T + C C G+ G++C+ + E P C G+C N Sbjct: 1097 CAFPGVC-PSGVCTN--TAGSFSCKDCDGGYRPSPLGDSCEDVDECEDPQSSCLGGECKN 1153 Query: 386 TADSYKCACP 415 T SY+C CP Sbjct: 1154 TVGSYQCLCP 1163 Score = 34.7 bits (76), Expect = 0.21 Identities = 22/71 (30%), Positives = 27/71 (38%), Gaps = 8/71 (11%) Frame = +2 Query: 236 NLCLNNGVCQEALT---EHGYVCLCAPGF----GGNNCDRIGESCRPGLCGPGKCMNTAD 394 N CL GVC E + C C G+ C + E C G C+NT Sbjct: 1012 NECLTPGVCAHGKCTNLEGSFRCSCEQGYEVTSDEKGCQDVDECASRASCPTGLCLNTEG 1071 Query: 395 SYKC-ACPVTY 424 S+ C AC Y Sbjct: 1072 SFACSACENGY 1082 Score = 34.3 bits (75), Expect = 0.27 Identities = 21/68 (30%), Positives = 31/68 (45%), Gaps = 6/68 (8%) Frame = +2 Query: 227 CAPN-LCLNNGVCQEALTEHGYVCLCAPGF----GGNNCDRIGE-SCRPGLCGPGKCMNT 388 CA + +C ++G C T+ + CLC GF G +C + E +CG C N Sbjct: 1307 CANDTMCGSHGFCDN--TDGSFRCLCDQGFEISPSGWDCVDVNECELMLAVCGAALCENV 1364 Query: 389 ADSYKCAC 412 S+ C C Sbjct: 1365 EGSFLCLC 1372 Score = 33.9 bits (74), Expect = 0.36 Identities = 13/30 (43%), Positives = 16/30 (53%) Frame = +2 Query: 323 NCDRIGESCRPGLCGPGKCMNTADSYKCAC 412 +C I E GLC +C+NT SY C C Sbjct: 619 HCQDINECLTLGLCKDAECVNTRGSYLCTC 648 Score = 33.9 bits (74), Expect = 0.36 Identities = 26/74 (35%), Positives = 33/74 (44%), Gaps = 6/74 (8%) Frame = +2 Query: 203 ENVQNCFTCAPNLCLNNGVCQEALTEHGYVCLCAPGFG----GNNCDRIGESCRPG--LC 364 ++V C T P C+ G C TE + CLC GF C I E G +C Sbjct: 1217 QDVDECATTDP--CVG-GHCVN--TEGSFNCLCETGFQPSPESGECVDIDECEDYGDPVC 1271 Query: 365 GPGKCMNTADSYKC 406 G KC N+ SY+C Sbjct: 1272 GTWKCENSPGSYRC 1285 Score = 31.5 bits (68), Expect = 1.9 Identities = 23/71 (32%), Positives = 26/71 (36%), Gaps = 10/71 (14%) Frame = +2 Query: 251 NGVCQEALTEHGYVCLCAPGF----------GGNNCDRIGESCRPGLCGPGKCMNTADSY 400 NG C GY C C GF N CD + LC G C NT SY Sbjct: 1745 NGRCVRV--REGYTCDCFEGFQLDAAHMACVDVNECDDLNGPAV--LCVHGYCENTEGSY 1800 Query: 401 KCACPVTYTGK 433 +C C Y + Sbjct: 1801 RCHCSPGYVAE 1811 >AB209865-1|BAD93102.1| 1700|Homo sapiens latent transforming growth factor beta binding protein 2 variant protein. Length = 1700 Score = 50.8 bits (116), Expect = 3e-06 Identities = 26/67 (38%), Positives = 32/67 (47%), Gaps = 8/67 (11%) Frame = +2 Query: 236 NLCLNNGVCQ---EALTEHG-YVCLCAPGF----GGNNCDRIGESCRPGLCGPGKCMNTA 391 N C+ C E L HG + CLCAPGF GG +C + E C G C+NT Sbjct: 1057 NECMGEEHCAPHGECLNSHGSFFCLCAPGFVSAEGGTSCQDVDECATTDPCVGGHCVNTE 1116 Query: 392 DSYKCAC 412 S+ C C Sbjct: 1117 GSFNCLC 1123 Score = 48.4 bits (110), Expect = 2e-05 Identities = 28/73 (38%), Positives = 34/73 (46%), Gaps = 4/73 (5%) Frame = +2 Query: 206 NVQNCFTCAPNLCLNNGVCQEALTEHGYVCLCAPGF----GGNNCDRIGESCRPGLCGPG 373 + C P LC NG C T GYVCLC PGF C+ E C+ C G Sbjct: 1364 DADECVIFGPGLC-PNGRCLN--TVPGYVCLCNPGFHYDASHKKCEDHDE-CQDLACENG 1419 Query: 374 KCMNTADSYKCAC 412 +C+NT S+ C C Sbjct: 1420 ECVNTEGSFHCFC 1432 Score = 47.2 bits (107), Expect = 4e-05 Identities = 28/74 (37%), Positives = 35/74 (47%), Gaps = 7/74 (9%) Frame = +2 Query: 236 NLCLNNGVC---QEALTEHGYVCLCAPGF---GGNNCDRIGESCRPGLCGPGKCMNTADS 397 N C GVC Q TE Y C C G+ +C I E PG C G+C+N+ S Sbjct: 811 NECEQPGVCSGGQCTNTEGSYHCECDQGYIMVRKGHCQDINECRHPGTCPDGRCVNSPGS 870 Query: 398 YKC-ACPVTYTGKN 436 Y C AC Y G++ Sbjct: 871 YTCLACEEGYRGQS 884 Score = 46.4 bits (105), Expect = 6e-05 Identities = 24/72 (33%), Positives = 30/72 (41%), Gaps = 6/72 (8%) Frame = +2 Query: 227 CAPNLCLNNGVCQEALTEHGYVCLCAPGF------GGNNCDRIGESCRPGLCGPGKCMNT 388 C + C G C + Y C C PG+ C I E +PG+C G+C NT Sbjct: 770 CLRDPCKGKGRCINRVGS--YSCFCYPGYTLATSGATQECQDINECEQPGVCSGGQCTNT 827 Query: 389 ADSYKCACPVTY 424 SY C C Y Sbjct: 828 EGSYHCECDQGY 839 Score = 46.4 bits (105), Expect = 6e-05 Identities = 23/69 (33%), Positives = 33/69 (47%), Gaps = 6/69 (8%) Frame = +2 Query: 236 NLCLNNGVCQEALTEHG---YVCL-CAPGFGGNN--CDRIGESCRPGLCGPGKCMNTADS 397 N C + G C + + Y CL C G+ G + C + E PG+C GKC N S Sbjct: 851 NECRHPGTCPDGRCVNSPGSYTCLACEEGYRGQSGSCVDVNECLTPGVCAHGKCTNLEGS 910 Query: 398 YKCACPVTY 424 ++C+C Y Sbjct: 911 FRCSCEQGY 919 Score = 44.0 bits (99), Expect = 3e-04 Identities = 26/84 (30%), Positives = 34/84 (40%), Gaps = 4/84 (4%) Frame = +2 Query: 188 LALEKENVQNCFTCAPNLCLNNGVCQEALTEHGYVCLCAPGF----GGNNCDRIGESCRP 355 + L + C A N+C G C GY C+C+PG+ C E R Sbjct: 717 VTLSTPGIDRCAAGATNVC-GPGTCVNL--PDGYRCVCSPGYQLHPSQAYCTDDNECLRD 773 Query: 356 GLCGPGKCMNTADSYKCACPVTYT 427 G G+C+N SY C C YT Sbjct: 774 PCKGKGRCINRVGSYSCFCYPGYT 797 Score = 41.9 bits (94), Expect = 0.001 Identities = 23/75 (30%), Positives = 34/75 (45%), Gaps = 5/75 (6%) Frame = +2 Query: 197 EKENVQNCFTCAPNLCLNNGVCQEALTEHGYVC-LCAPGF----GGNNCDRIGESCRPGL 361 +++ Q+ CA G+C TE + C C G+ G C+ + E PG+ Sbjct: 924 DEKGCQDVDECASRASCPTGLCLN--TEGSFACSACENGYWVNEDGTACEDLDECAFPGV 981 Query: 362 CGPGKCMNTADSYKC 406 C G C NTA S+ C Sbjct: 982 CPSGVCTNTAGSFSC 996 Score = 36.7 bits (81), Expect = 0.052 Identities = 25/70 (35%), Positives = 35/70 (50%), Gaps = 7/70 (10%) Frame = +2 Query: 227 CA-PNLCLNNGVCQEALTEHGYVCL-CAPGFG----GNNCDRIGESCRP-GLCGPGKCMN 385 CA P +C +GVC T + C C G+ G++C+ + E P C G+C N Sbjct: 976 CAFPGVC-PSGVCTN--TAGSFSCKDCDGGYRPSPLGDSCEDVDECEDPQSSCLGGECKN 1032 Query: 386 TADSYKCACP 415 T SY+C CP Sbjct: 1033 TVGSYQCLCP 1042 Score = 34.7 bits (76), Expect = 0.21 Identities = 22/71 (30%), Positives = 27/71 (38%), Gaps = 8/71 (11%) Frame = +2 Query: 236 NLCLNNGVCQEALT---EHGYVCLCAPGF----GGNNCDRIGESCRPGLCGPGKCMNTAD 394 N CL GVC E + C C G+ C + E C G C+NT Sbjct: 891 NECLTPGVCAHGKCTNLEGSFRCSCEQGYEVTSDEKGCQDVDECASRASCPTGLCLNTEG 950 Query: 395 SYKC-ACPVTY 424 S+ C AC Y Sbjct: 951 SFACSACENGY 961 Score = 34.3 bits (75), Expect = 0.27 Identities = 21/68 (30%), Positives = 31/68 (45%), Gaps = 6/68 (8%) Frame = +2 Query: 227 CAPN-LCLNNGVCQEALTEHGYVCLCAPGF----GGNNCDRIGE-SCRPGLCGPGKCMNT 388 CA + +C ++G C T+ + CLC GF G +C + E +CG C N Sbjct: 1186 CANDTMCGSHGFCDN--TDGSFRCLCDQGFEISPSGWDCVDVNECELMLAVCGAALCENV 1243 Query: 389 ADSYKCAC 412 S+ C C Sbjct: 1244 EGSFLCLC 1251 Score = 33.9 bits (74), Expect = 0.36 Identities = 13/30 (43%), Positives = 16/30 (53%) Frame = +2 Query: 323 NCDRIGESCRPGLCGPGKCMNTADSYKCAC 412 +C I E GLC +C+NT SY C C Sbjct: 498 HCQDINECLTLGLCKDAECVNTRGSYLCTC 527 Score = 33.9 bits (74), Expect = 0.36 Identities = 26/74 (35%), Positives = 33/74 (44%), Gaps = 6/74 (8%) Frame = +2 Query: 203 ENVQNCFTCAPNLCLNNGVCQEALTEHGYVCLCAPGFG----GNNCDRIGESCRPG--LC 364 ++V C T P C+ G C TE + CLC GF C I E G +C Sbjct: 1096 QDVDECATTDP--CVG-GHCVN--TEGSFNCLCETGFQPSPESGECVDIDECEDYGDPVC 1150 Query: 365 GPGKCMNTADSYKC 406 G KC N+ SY+C Sbjct: 1151 GTWKCENSPGSYRC 1164 Score = 31.5 bits (68), Expect = 1.9 Identities = 23/71 (32%), Positives = 26/71 (36%), Gaps = 10/71 (14%) Frame = +2 Query: 251 NGVCQEALTEHGYVCLCAPGF----------GGNNCDRIGESCRPGLCGPGKCMNTADSY 400 NG C GY C C GF N CD + LC G C NT SY Sbjct: 1624 NGRCVRV--REGYTCDCFEGFQLDAAHMACVDVNECDDLNGPAV--LCVHGYCENTEGSY 1679 Query: 401 KCACPVTYTGK 433 +C C Y + Sbjct: 1680 RCHCSPGYVAE 1690 >U33837-1|AAB41649.1| 4655|Homo sapiens gp330 precursor protein. Length = 4655 Score = 50.4 bits (115), Expect = 4e-06 Identities = 30/73 (41%), Positives = 37/73 (50%), Gaps = 5/73 (6%) Frame = +2 Query: 224 TCAPNLCLNNGVCQEALTEHGYVCLCAPGFGGNNCDR-----IGESCRPGLCGPGKCMNT 388 TCA N+C N C + L E G++C C GF N DR I E + G C P C NT Sbjct: 3969 TCAENICEQN--CTQ-LNEGGFICSCTAGFETNVFDRTSCLDINECEQFGTC-PQHCRNT 4024 Query: 389 ADSYKCACPVTYT 427 SY+C C +T Sbjct: 4025 KGSYECVCADGFT 4037 Score = 36.7 bits (81), Expect = 0.052 Identities = 27/84 (32%), Positives = 34/84 (40%), Gaps = 11/84 (13%) Frame = +2 Query: 227 CAPNLC--LNNGVCQEALTE-HGYVCLCAPGF----GGNNCDRIGESCRPGLCGPGKCMN 385 C N C N G E + E G CLC GF C+ I E G C C N Sbjct: 1348 CNGNSCSDFNGGCTHECVQEPFGAKCLCPLGFLLANDSKTCEDIDECDILGSCSQ-HCYN 1406 Query: 386 TADSYKCACPVTY----TGKNCEV 445 S++C+C Y G+ C+V Sbjct: 1407 MRGSFRCSCDTGYMLESDGRTCKV 1430 Score = 36.7 bits (81), Expect = 0.052 Identities = 35/117 (29%), Positives = 47/117 (40%), Gaps = 10/117 (8%) Frame = +2 Query: 140 CISMLILGNEEKNIMALALEKE-NVQNCFTCAPNLCLNNGVCQEALTEHGYVCLCAPGF- 313 CI M+ L N + + + EK + C + + C +N C + LT + C C PG+ Sbjct: 3087 CIEMMKLCNHLDDCLDNSDEKGCGINECHDPSISGCDHN--CTDTLTS--FYCSCRPGYK 3142 Query: 314 ---GGNNCDRIGESCR-PGLCGPGKCMNTADSYKCACPVTY----TGKNCEVKQLIE 460 C I E P +C KC N SY C C Y GK C IE Sbjct: 3143 LMSDKRTCVDIDECTEMPFVCSQ-KCENVIGSYICKCAPGYLREPDGKTCRQNSNIE 3198 Score = 35.5 bits (78), Expect = 0.12 Identities = 29/85 (34%), Positives = 34/85 (40%), Gaps = 14/85 (16%) Frame = +2 Query: 233 PNLCLNNGVCQEA--LTEHGYVCLCAPGFG-----GNNCDRIGESCRPGLCGPGKCMNTA 391 PNLC +C L GY C C G CD E L P +CM+ Sbjct: 4331 PNLCKQ--ICSHLCLLRPGGYSCACPQGSSFIEGSTTECDAAIE-LPINLPPPCRCMHGG 4387 Query: 392 DSY-------KCACPVTYTGKNCEV 445 + Y KC CP YTGK CE+ Sbjct: 4388 NCYFDETDLPKCKCPSGYTGKYCEM 4412 Database: human Posted date: Oct 23, 2007 1:18 PM Number of letters in database: 76,859,062 Number of sequences in database: 237,096 Lambda K H 0.318 0.134 0.401 Gapped Lambda K H 0.279 0.0580 0.190 Matrix: BLOSUM62 Gap Penalties: Existence: 9, Extension: 2 Number of Hits to DB: 84,971,021 Number of Sequences: 237096 Number of extensions: 1986524 Number of successful extensions: 17722 Number of sequences better than 10.0: 500 Number of HSP's better than 10.0 without gapping: 9916 Number of HSP's successfully gapped in prelim test: 0 Number of HSP's that attempted gapping in prelim test: 0 Number of HSP's gapped (non-prelim): 14857 length of database: 76,859,062 effective HSP length: 85 effective length of database: 56,705,902 effective search space used: 5216942984 frameshift window, decay const: 40, 0.1 T: 12 A: 40 X1: 16 ( 7.3 bits) X2: 37 (14.9 bits) X3: 62 (25.0 bits) S1: 41 (21.7 bits)
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