Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= I10A02NGRL0002_I11
(558 letters)
Database: human
237,096 sequences; 76,859,062 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
M23294-1|AAA52645.1| 556|Homo sapiens beta-hexosaminidase beta-... 43 8e-04
M19735-1|AAA68620.1| 544|Homo sapiens beta-hexosaminidase beta-... 43 8e-04
M13519-1|AAA51828.1| 572|Homo sapiens HEXB protein. 43 8e-04
BT009919-1|AAP88921.1| 556|Homo sapiens hexosaminidase B (beta ... 43 8e-04
BC017378-1|AAH17378.1| 556|Homo sapiens hexosaminidase B (beta ... 43 8e-04
AF378118-1|AAM46114.1| 556|Homo sapiens cervical cancer proto-o... 43 8e-04
S62076-1|AAD13932.1| 529|Homo sapiens HEXA protein. 35 0.22
M16424-1|AAB00965.1| 529|Homo sapiens HEXA protein. 35 0.22
BC084537-1|AAH84537.1| 529|Homo sapiens hexosaminidase A (alpha... 35 0.22
BC018927-1|AAH18927.1| 529|Homo sapiens hexosaminidase A (alpha... 35 0.22
AK222502-1|BAD96222.1| 529|Homo sapiens hexosaminidase A prepro... 35 0.22
M13520-1|AAA51827.1| 490|Homo sapiens HEXA protein. 34 0.29
AL022152-2|CAD27434.1| 1142|Homo sapiens melanoma antigen family... 31 2.1
AK128570-1|BAC87504.1| 851|Homo sapiens protein ( Homo sapiens ... 31 2.1
AF064589-1|AAC18837.1| 1142|Homo sapiens melanoma-associated ant... 31 2.1
AF056334-1|AAC24227.1| 1142|Homo sapiens cancer/testis antigen C... 31 2.1
BC060796-1|AAH60796.1| 684|Homo sapiens coiled-coil domain cont... 30 6.3
AY254201-1|AAP13075.1| 682|Homo sapiens aaa-protein protein. 30 6.3
AY204751-1|AAP13576.1| 5058|Homo sapiens ABC A13 protein. 30 6.3
AY009105-1|AAG49396.1| 497|Homo sapiens testis-specific protein... 30 6.3
AF501281-1|AAO59914.1| 2127|Homo sapiens ATP binding cassette tr... 30 6.3
>M23294-1|AAA52645.1| 556|Homo sapiens beta-hexosaminidase
beta-subunit protein.
Length = 556
Score = 42.7 bits (96), Expect = 8e-04
Identities = 23/57 (40%), Positives = 30/57 (52%), Gaps = 3/57 (5%)
Frame = +3
Query: 381 VQELHVELT--APCEKLPYFGMDESYNLXXXX-XXXXXXXXIWGVIRGLETWSQLFY 542
VQ+L V +T + C+ P DESY L +WG +RGLET+SQL Y
Sbjct: 124 VQQLLVSITLQSECDAFPNISSDESYTLLVKEPVAVLKANRVWGALRGLETFSQLVY 180
>M19735-1|AAA68620.1| 544|Homo sapiens beta-hexosaminidase
beta-subunit protein.
Length = 544
Score = 42.7 bits (96), Expect = 8e-04
Identities = 23/57 (40%), Positives = 30/57 (52%), Gaps = 3/57 (5%)
Frame = +3
Query: 381 VQELHVELT--APCEKLPYFGMDESYNLXXXX-XXXXXXXXIWGVIRGLETWSQLFY 542
VQ+L V +T + C+ P DESY L +WG +RGLET+SQL Y
Sbjct: 112 VQQLLVSITLQSECDAFPNISSDESYTLLVKEPVAVLKANRVWGALRGLETFSQLVY 168
>M13519-1|AAA51828.1| 572|Homo sapiens HEXB protein.
Length = 572
Score = 42.7 bits (96), Expect = 8e-04
Identities = 23/57 (40%), Positives = 30/57 (52%), Gaps = 3/57 (5%)
Frame = +3
Query: 381 VQELHVELT--APCEKLPYFGMDESYNLXXXX-XXXXXXXXIWGVIRGLETWSQLFY 542
VQ+L V +T + C+ P DESY L +WG +RGLET+SQL Y
Sbjct: 140 VQQLLVSITLQSECDAFPNISSDESYTLLVKEPVAVLKANRVWGALRGLETFSQLVY 196
>BT009919-1|AAP88921.1| 556|Homo sapiens hexosaminidase B (beta
polypeptide) protein.
Length = 556
Score = 42.7 bits (96), Expect = 8e-04
Identities = 23/57 (40%), Positives = 30/57 (52%), Gaps = 3/57 (5%)
Frame = +3
Query: 381 VQELHVELT--APCEKLPYFGMDESYNLXXXX-XXXXXXXXIWGVIRGLETWSQLFY 542
VQ+L V +T + C+ P DESY L +WG +RGLET+SQL Y
Sbjct: 124 VQQLLVSITLQSECDAFPNISSDESYTLLVKEPVAVLKANRVWGALRGLETFSQLVY 180
>BC017378-1|AAH17378.1| 556|Homo sapiens hexosaminidase B (beta
polypeptide) protein.
Length = 556
Score = 42.7 bits (96), Expect = 8e-04
Identities = 23/57 (40%), Positives = 30/57 (52%), Gaps = 3/57 (5%)
Frame = +3
Query: 381 VQELHVELT--APCEKLPYFGMDESYNLXXXX-XXXXXXXXIWGVIRGLETWSQLFY 542
VQ+L V +T + C+ P DESY L +WG +RGLET+SQL Y
Sbjct: 124 VQQLLVSITLQSECDAFPNISSDESYTLLVKEPVAVLKANRVWGALRGLETFSQLVY 180
>AF378118-1|AAM46114.1| 556|Homo sapiens cervical cancer
proto-oncogene 7 protein.
Length = 556
Score = 42.7 bits (96), Expect = 8e-04
Identities = 23/57 (40%), Positives = 30/57 (52%), Gaps = 3/57 (5%)
Frame = +3
Query: 381 VQELHVELT--APCEKLPYFGMDESYNLXXXX-XXXXXXXXIWGVIRGLETWSQLFY 542
VQ+L V +T + C+ P DESY L +WG +RGLET+SQL Y
Sbjct: 124 VQQLLVSITLQSECDAFPNISSDESYTLLVKEPVAVLKANRVWGALRGLETFSQLVY 180
>S62076-1|AAD13932.1| 529|Homo sapiens HEXA protein.
Length = 529
Score = 34.7 bits (76), Expect = 0.22
Identities = 39/143 (27%), Positives = 59/143 (41%), Gaps = 9/143 (6%)
Frame = +3
Query: 141 VWPKPQ-IQVKDDKY------YTFDPAVFTVKEPFQKCDFLTKALERYQFLVRDLHRITR 299
+WP PQ Q D +Y + F V + +P C L +A +RY RDL +
Sbjct: 23 LWPWPQNFQTSDQRYVLYPNNFQFQYDVSSAAQP--GCSVLDEAFQRY----RDLLFGSG 76
Query: 300 RFVKRSLGSQYRSLDDEAANDERFQGTVQELHVELTAP-CEKLPYFGMDESYNLXXXXXX 476
+ + L + +L+ L V + P C +LP E+Y L
Sbjct: 77 SWPRPYLTGKRHTLEKNV------------LVVSVVTPGCNQLPTLESVENYTLTINDDQ 124
Query: 477 -XXXXXXIWGVIRGLETWSQLFY 542
+WG +RGLET+SQL +
Sbjct: 125 CLLLSETVWGALRGLETFSQLVW 147
>M16424-1|AAB00965.1| 529|Homo sapiens HEXA protein.
Length = 529
Score = 34.7 bits (76), Expect = 0.22
Identities = 39/143 (27%), Positives = 59/143 (41%), Gaps = 9/143 (6%)
Frame = +3
Query: 141 VWPKPQ-IQVKDDKY------YTFDPAVFTVKEPFQKCDFLTKALERYQFLVRDLHRITR 299
+WP PQ Q D +Y + F V + +P C L +A +RY RDL +
Sbjct: 23 LWPWPQNFQTSDQRYVLYPNNFQFQYDVSSAAQP--GCSVLDEAFQRY----RDLLFGSG 76
Query: 300 RFVKRSLGSQYRSLDDEAANDERFQGTVQELHVELTAP-CEKLPYFGMDESYNLXXXXXX 476
+ + L + +L+ L V + P C +LP E+Y L
Sbjct: 77 SWPRPYLTGKRHTLEKNV------------LVVSVVTPGCNQLPTLESVENYTLTINDDQ 124
Query: 477 -XXXXXXIWGVIRGLETWSQLFY 542
+WG +RGLET+SQL +
Sbjct: 125 CLLLSETVWGALRGLETFSQLVW 147
>BC084537-1|AAH84537.1| 529|Homo sapiens hexosaminidase A (alpha
polypeptide) protein.
Length = 529
Score = 34.7 bits (76), Expect = 0.22
Identities = 39/143 (27%), Positives = 59/143 (41%), Gaps = 9/143 (6%)
Frame = +3
Query: 141 VWPKPQ-IQVKDDKY------YTFDPAVFTVKEPFQKCDFLTKALERYQFLVRDLHRITR 299
+WP PQ Q D +Y + F V + +P C L +A +RY RDL +
Sbjct: 23 LWPWPQNFQTSDQRYVLYPNNFQFQYDVSSAAQP--GCSVLDEAFQRY----RDLLFGSG 76
Query: 300 RFVKRSLGSQYRSLDDEAANDERFQGTVQELHVELTAP-CEKLPYFGMDESYNLXXXXXX 476
+ + L + +L+ L V + P C +LP E+Y L
Sbjct: 77 SWPRPYLTGKRHTLEKNV------------LVVSVVTPGCNQLPTLESVENYTLTINDDQ 124
Query: 477 -XXXXXXIWGVIRGLETWSQLFY 542
+WG +RGLET+SQL +
Sbjct: 125 CLLLSETVWGALRGLETFSQLVW 147
>BC018927-1|AAH18927.1| 529|Homo sapiens hexosaminidase A (alpha
polypeptide) protein.
Length = 529
Score = 34.7 bits (76), Expect = 0.22
Identities = 39/143 (27%), Positives = 59/143 (41%), Gaps = 9/143 (6%)
Frame = +3
Query: 141 VWPKPQ-IQVKDDKY------YTFDPAVFTVKEPFQKCDFLTKALERYQFLVRDLHRITR 299
+WP PQ Q D +Y + F V + +P C L +A +RY RDL +
Sbjct: 23 LWPWPQNFQTSDQRYVLYPNNFQFQYDVSSAAQP--GCSVLDEAFQRY----RDLLFGSG 76
Query: 300 RFVKRSLGSQYRSLDDEAANDERFQGTVQELHVELTAP-CEKLPYFGMDESYNLXXXXXX 476
+ + L + +L+ L V + P C +LP E+Y L
Sbjct: 77 SWPRPYLTGKRHTLEKNV------------LVVSVVTPGCNQLPTLESVENYTLTINDDQ 124
Query: 477 -XXXXXXIWGVIRGLETWSQLFY 542
+WG +RGLET+SQL +
Sbjct: 125 CLLLSETVWGALRGLETFSQLVW 147
>AK222502-1|BAD96222.1| 529|Homo sapiens hexosaminidase A
preproprotein variant protein.
Length = 529
Score = 34.7 bits (76), Expect = 0.22
Identities = 39/143 (27%), Positives = 59/143 (41%), Gaps = 9/143 (6%)
Frame = +3
Query: 141 VWPKPQ-IQVKDDKY------YTFDPAVFTVKEPFQKCDFLTKALERYQFLVRDLHRITR 299
+WP PQ Q D +Y + F V + +P C L +A +RY RDL +
Sbjct: 23 LWPWPQNFQTSDQRYVLYPNNFQFQYDVSSAAQP--GCSVLDEAFQRY----RDLLFGSG 76
Query: 300 RFVKRSLGSQYRSLDDEAANDERFQGTVQELHVELTAP-CEKLPYFGMDESYNLXXXXXX 476
+ + L + +L+ L V + P C +LP E+Y L
Sbjct: 77 SWPRPYLTGKRHTLEKNV------------LVVSVVTPGCNQLPTLESVENYTLTINDDQ 124
Query: 477 -XXXXXXIWGVIRGLETWSQLFY 542
+WG +RGLET+SQL +
Sbjct: 125 CLLLSETVWGALRGLETFSQLVW 147
>M13520-1|AAA51827.1| 490|Homo sapiens HEXA protein.
Length = 490
Score = 34.3 bits (75), Expect = 0.29
Identities = 17/48 (35%), Positives = 24/48 (50%), Gaps = 1/48 (2%)
Frame = +3
Query: 402 LTAPCEKLPYFGMDESYNLXXXXXX-XXXXXXIWGVIRGLETWSQLFY 542
+T C +LP E+Y L +WG +RGLET+SQL +
Sbjct: 61 VTPGCNQLPTLESVENYTLTINDDQCLLLSETVWGALRGLETFSQLVW 108
>AL022152-2|CAD27434.1| 1142|Homo sapiens melanoma antigen family C, 1
protein.
Length = 1142
Score = 31.5 bits (68), Expect = 2.1
Identities = 17/61 (27%), Positives = 27/61 (44%)
Frame = +3
Query: 168 KDDKYYTFDPAVFTVKEPFQKCDFLTKALERYQFLVRDLHRITRRFVKRSLGSQYRSLDD 347
K D+ F + VK+P K + LT + RY + R R F++ G R +D
Sbjct: 911 KVDELARFLLLKYQVKQPITKAEMLTNVISRYTGYFPVIFRKAREFIEILFGISLREVDP 970
Query: 348 E 350
+
Sbjct: 971 D 971
>AK128570-1|BAC87504.1| 851|Homo sapiens protein ( Homo sapiens
cDNA FLJ46729 fis, clone TRACH3019370, weakly similar
to ATP-binding cassette, sub-family A, member 1. ).
Length = 851
Score = 31.5 bits (68), Expect = 2.1
Identities = 19/91 (20%), Positives = 39/91 (42%), Gaps = 2/91 (2%)
Frame = +3
Query: 189 FDPAVFTVKEPFQKCDFLTKALERYQFLVRDLHRITRRFVKRSLGSQYRSLDDEAANDER 368
+ P + + QK ++ +++ + L L +T F + G + L + N
Sbjct: 75 YTPNTPEINKVIQKANYTFYIVDKLKTLSETLLEMTSLFQRSGSGQMFNQLQEALRNKFV 134
Query: 369 FQGTVQELHVELTAPCEKLPYFG--MDESYN 455
+LH+++ EKL +G +DE +N
Sbjct: 135 RNFVENQLHIDVDKLTEKLQTYGGLLDEMFN 165
>AF064589-1|AAC18837.1| 1142|Homo sapiens melanoma-associated antigen
protein.
Length = 1142
Score = 31.5 bits (68), Expect = 2.1
Identities = 17/61 (27%), Positives = 27/61 (44%)
Frame = +3
Query: 168 KDDKYYTFDPAVFTVKEPFQKCDFLTKALERYQFLVRDLHRITRRFVKRSLGSQYRSLDD 347
K D+ F + VK+P K + LT + RY + R R F++ G R +D
Sbjct: 911 KVDELARFLLLKYQVKQPITKAEMLTNVISRYTGYFPVIFRKAREFIEILFGISLREVDP 970
Query: 348 E 350
+
Sbjct: 971 D 971
>AF056334-1|AAC24227.1| 1142|Homo sapiens cancer/testis antigen CT7
protein.
Length = 1142
Score = 31.5 bits (68), Expect = 2.1
Identities = 17/61 (27%), Positives = 27/61 (44%)
Frame = +3
Query: 168 KDDKYYTFDPAVFTVKEPFQKCDFLTKALERYQFLVRDLHRITRRFVKRSLGSQYRSLDD 347
K D+ F + VK+P K + LT + RY + R R F++ G R +D
Sbjct: 911 KVDELARFLLLKYQVKQPITKAEMLTNVISRYTGYFPVIFRKAREFIEILFGISLREVDP 970
Query: 348 E 350
+
Sbjct: 971 D 971
>BC060796-1|AAH60796.1| 684|Homo sapiens coiled-coil domain
containing 62 protein.
Length = 684
Score = 29.9 bits (64), Expect = 6.3
Identities = 16/68 (23%), Positives = 35/68 (51%)
Frame = +3
Query: 159 IQVKDDKYYTFDPAVFTVKEPFQKCDFLTKALERYQFLVRDLHRITRRFVKRSLGSQYRS 338
I++K +K D +FTV+ +K + L A + + +LH + + +VK+ Q+ +
Sbjct: 241 IRLKQEKSCLHDELLFTVEREKRKDELLNIAKSKQERTNSELHNLRQIYVKQQSDLQFLN 300
Query: 339 LDDEAAND 362
+ E + +
Sbjct: 301 FNVENSQE 308
>AY254201-1|AAP13075.1| 682|Homo sapiens aaa-protein protein.
Length = 682
Score = 29.9 bits (64), Expect = 6.3
Identities = 16/68 (23%), Positives = 35/68 (51%)
Frame = +3
Query: 159 IQVKDDKYYTFDPAVFTVKEPFQKCDFLTKALERYQFLVRDLHRITRRFVKRSLGSQYRS 338
I++K +K D +FTV+ +K + L A + + +LH + + +VK+ Q+ +
Sbjct: 241 IRLKQEKSCLHDELLFTVEREKRKDELLNIAKSKQERTNSELHNLRQIYVKQQSDLQFLN 300
Query: 339 LDDEAAND 362
+ E + +
Sbjct: 301 FNVENSQE 308
>AY204751-1|AAP13576.1| 5058|Homo sapiens ABC A13 protein.
Length = 5058
Score = 29.9 bits (64), Expect = 6.3
Identities = 18/91 (19%), Positives = 39/91 (42%), Gaps = 2/91 (2%)
Frame = +3
Query: 189 FDPAVFTVKEPFQKCDFLTKALERYQFLVRDLHRITRRFVKRSLGSQYRSLDDEAANDER 368
+ P + + QK ++ +++ + L L ++ F + G + L + N
Sbjct: 3320 YTPNTPEINKVIQKANYTFYIVDKLKTLSETLLEMSSLFQRSGSGQMFNQLQEALRNKFV 3379
Query: 369 FQGTVQELHVELTAPCEKLPYFG--MDESYN 455
+LH+++ EKL +G +DE +N
Sbjct: 3380 RNFVENQLHIDVDKLTEKLQTYGGLLDEMFN 3410
>AY009105-1|AAG49396.1| 497|Homo sapiens testis-specific protein
TSP-NY protein.
Length = 497
Score = 29.9 bits (64), Expect = 6.3
Identities = 16/68 (23%), Positives = 35/68 (51%)
Frame = +3
Query: 159 IQVKDDKYYTFDPAVFTVKEPFQKCDFLTKALERYQFLVRDLHRITRRFVKRSLGSQYRS 338
I++K +K D +FTV+ +K + L A + + +LH + + +VK+ Q+ +
Sbjct: 56 IRLKQEKSCLHDELLFTVEREKRKDELLNIAKSKQERTNSELHNLRQIYVKQQSDLQFLN 115
Query: 339 LDDEAAND 362
+ E + +
Sbjct: 116 FNVENSQE 123
>AF501281-1|AAO59914.1| 2127|Homo sapiens ATP binding cassette
transporter A13 protein.
Length = 2127
Score = 29.9 bits (64), Expect = 6.3
Identities = 18/91 (19%), Positives = 39/91 (42%), Gaps = 2/91 (2%)
Frame = +3
Query: 189 FDPAVFTVKEPFQKCDFLTKALERYQFLVRDLHRITRRFVKRSLGSQYRSLDDEAANDER 368
+ P + + QK ++ +++ + L L ++ F + G + L + N
Sbjct: 388 YTPNTPEINKVIQKANYTFYIVDKLKTLSETLLEMSSLFQRSGSGQMFNQLQEALRNKFV 447
Query: 369 FQGTVQELHVELTAPCEKLPYFG--MDESYN 455
+LH+++ EKL +G +DE +N
Sbjct: 448 RNFVENQLHIDVDKLTEKLQTYGGLLDEMFN 478
Database: human
Posted date: Oct 23, 2007 1:18 PM
Number of letters in database: 76,859,062
Number of sequences in database: 237,096
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 88,340,001
Number of Sequences: 237096
Number of extensions: 1978881
Number of successful extensions: 4019
Number of sequences better than 10.0: 21
Number of HSP's better than 10.0 without gapping: 3917
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 4019
length of database: 76,859,062
effective HSP length: 86
effective length of database: 56,468,806
effective search space used: 5590411794
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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