Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= I10A02NGRL0002_D03
(504 letters)
Database: human
237,096 sequences; 76,859,062 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
M23294-1|AAA52645.1| 556|Homo sapiens beta-hexosaminidase beta-... 145 9e-35
M19735-1|AAA68620.1| 544|Homo sapiens beta-hexosaminidase beta-... 145 9e-35
M13519-1|AAA51828.1| 572|Homo sapiens HEXB protein. 145 9e-35
BT009919-1|AAP88921.1| 556|Homo sapiens hexosaminidase B (beta ... 145 9e-35
BC017378-1|AAH17378.1| 556|Homo sapiens hexosaminidase B (beta ... 145 9e-35
AF378118-1|AAM46114.1| 556|Homo sapiens cervical cancer proto-o... 145 9e-35
S62076-1|AAD13932.1| 529|Homo sapiens HEXA protein. 138 8e-33
M16424-1|AAB00965.1| 529|Homo sapiens HEXA protein. 138 8e-33
M13520-1|AAA51827.1| 490|Homo sapiens HEXA protein. 138 8e-33
BC084537-1|AAH84537.1| 529|Homo sapiens hexosaminidase A (alpha... 138 8e-33
BC018927-1|AAH18927.1| 529|Homo sapiens hexosaminidase A (alpha... 138 8e-33
AK222502-1|BAD96222.1| 529|Homo sapiens hexosaminidase A prepro... 138 8e-33
BC001138-1|AAH01138.2| 409|Homo sapiens HEXA protein protein. 133 3e-31
M34906-1|AAA51829.1| 58|Homo sapiens beta-hexosaminidase beta-... 63 6e-10
AY643499-1|AAV48875.1| 331|Homo sapiens ENC-1AS protein. 63 6e-10
>M23294-1|AAA52645.1| 556|Homo sapiens beta-hexosaminidase
beta-subunit protein.
Length = 556
Score = 145 bits (351), Expect = 9e-35
Identities = 72/138 (52%), Positives = 89/138 (64%), Gaps = 3/138 (2%)
Frame = +3
Query: 90 VQELHVELT--APCEKLPYFGMDESYNLXXXX-XXXXXXXXIWGVIRGLETWSQLFYLTN 260
VQ+L V +T + C+ P DESY L +WG +RGLET+SQL Y +
Sbjct: 124 VQQLLVSITLQSECDAFPNISSDESYTLLVKEPVAVLKANRVWGALRGLETFSQLVY-QD 182
Query: 261 DFRELRINSTDIYDYPRYAHRGLLLDTSRHYLSLSKILKNIDAMAANKMNVLHWHIVDDQ 440
+ IN + I D PR++HRG+L+DTSRHYL + ILK +DAMA NK NVLHWHIVDDQ
Sbjct: 183 SYGTFTINESTIIDSPRFSHRGILIDTSRHYLPVKIILKTLDAMAFNKFNVLHWHIVDDQ 242
Query: 441 SFPYHSEKFPELSRLGAY 494
SFPY S FPELS G+Y
Sbjct: 243 SFPYQSITFPELSNKGSY 260
>M19735-1|AAA68620.1| 544|Homo sapiens beta-hexosaminidase
beta-subunit protein.
Length = 544
Score = 145 bits (351), Expect = 9e-35
Identities = 72/138 (52%), Positives = 89/138 (64%), Gaps = 3/138 (2%)
Frame = +3
Query: 90 VQELHVELT--APCEKLPYFGMDESYNLXXXX-XXXXXXXXIWGVIRGLETWSQLFYLTN 260
VQ+L V +T + C+ P DESY L +WG +RGLET+SQL Y +
Sbjct: 112 VQQLLVSITLQSECDAFPNISSDESYTLLVKEPVAVLKANRVWGALRGLETFSQLVY-QD 170
Query: 261 DFRELRINSTDIYDYPRYAHRGLLLDTSRHYLSLSKILKNIDAMAANKMNVLHWHIVDDQ 440
+ IN + I D PR++HRG+L+DTSRHYL + ILK +DAMA NK NVLHWHIVDDQ
Sbjct: 171 SYGTFTINESTIIDSPRFSHRGILIDTSRHYLPVKIILKTLDAMAFNKFNVLHWHIVDDQ 230
Query: 441 SFPYHSEKFPELSRLGAY 494
SFPY S FPELS G+Y
Sbjct: 231 SFPYQSITFPELSNKGSY 248
>M13519-1|AAA51828.1| 572|Homo sapiens HEXB protein.
Length = 572
Score = 145 bits (351), Expect = 9e-35
Identities = 72/138 (52%), Positives = 89/138 (64%), Gaps = 3/138 (2%)
Frame = +3
Query: 90 VQELHVELT--APCEKLPYFGMDESYNLXXXX-XXXXXXXXIWGVIRGLETWSQLFYLTN 260
VQ+L V +T + C+ P DESY L +WG +RGLET+SQL Y +
Sbjct: 140 VQQLLVSITLQSECDAFPNISSDESYTLLVKEPVAVLKANRVWGALRGLETFSQLVY-QD 198
Query: 261 DFRELRINSTDIYDYPRYAHRGLLLDTSRHYLSLSKILKNIDAMAANKMNVLHWHIVDDQ 440
+ IN + I D PR++HRG+L+DTSRHYL + ILK +DAMA NK NVLHWHIVDDQ
Sbjct: 199 SYGTFTINESTIIDSPRFSHRGILIDTSRHYLPVKIILKTLDAMAFNKFNVLHWHIVDDQ 258
Query: 441 SFPYHSEKFPELSRLGAY 494
SFPY S FPELS G+Y
Sbjct: 259 SFPYQSITFPELSNKGSY 276
>BT009919-1|AAP88921.1| 556|Homo sapiens hexosaminidase B (beta
polypeptide) protein.
Length = 556
Score = 145 bits (351), Expect = 9e-35
Identities = 72/138 (52%), Positives = 89/138 (64%), Gaps = 3/138 (2%)
Frame = +3
Query: 90 VQELHVELT--APCEKLPYFGMDESYNLXXXX-XXXXXXXXIWGVIRGLETWSQLFYLTN 260
VQ+L V +T + C+ P DESY L +WG +RGLET+SQL Y +
Sbjct: 124 VQQLLVSITLQSECDAFPNISSDESYTLLVKEPVAVLKANRVWGALRGLETFSQLVY-QD 182
Query: 261 DFRELRINSTDIYDYPRYAHRGLLLDTSRHYLSLSKILKNIDAMAANKMNVLHWHIVDDQ 440
+ IN + I D PR++HRG+L+DTSRHYL + ILK +DAMA NK NVLHWHIVDDQ
Sbjct: 183 SYGTFTINESTIIDSPRFSHRGILIDTSRHYLPVKIILKTLDAMAFNKFNVLHWHIVDDQ 242
Query: 441 SFPYHSEKFPELSRLGAY 494
SFPY S FPELS G+Y
Sbjct: 243 SFPYQSITFPELSNKGSY 260
>BC017378-1|AAH17378.1| 556|Homo sapiens hexosaminidase B (beta
polypeptide) protein.
Length = 556
Score = 145 bits (351), Expect = 9e-35
Identities = 72/138 (52%), Positives = 89/138 (64%), Gaps = 3/138 (2%)
Frame = +3
Query: 90 VQELHVELT--APCEKLPYFGMDESYNLXXXX-XXXXXXXXIWGVIRGLETWSQLFYLTN 260
VQ+L V +T + C+ P DESY L +WG +RGLET+SQL Y +
Sbjct: 124 VQQLLVSITLQSECDAFPNISSDESYTLLVKEPVAVLKANRVWGALRGLETFSQLVY-QD 182
Query: 261 DFRELRINSTDIYDYPRYAHRGLLLDTSRHYLSLSKILKNIDAMAANKMNVLHWHIVDDQ 440
+ IN + I D PR++HRG+L+DTSRHYL + ILK +DAMA NK NVLHWHIVDDQ
Sbjct: 183 SYGTFTINESTIIDSPRFSHRGILIDTSRHYLPVKIILKTLDAMAFNKFNVLHWHIVDDQ 242
Query: 441 SFPYHSEKFPELSRLGAY 494
SFPY S FPELS G+Y
Sbjct: 243 SFPYQSITFPELSNKGSY 260
>AF378118-1|AAM46114.1| 556|Homo sapiens cervical cancer
proto-oncogene 7 protein.
Length = 556
Score = 145 bits (351), Expect = 9e-35
Identities = 72/138 (52%), Positives = 89/138 (64%), Gaps = 3/138 (2%)
Frame = +3
Query: 90 VQELHVELT--APCEKLPYFGMDESYNLXXXX-XXXXXXXXIWGVIRGLETWSQLFYLTN 260
VQ+L V +T + C+ P DESY L +WG +RGLET+SQL Y +
Sbjct: 124 VQQLLVSITLQSECDAFPNISSDESYTLLVKEPVAVLKANRVWGALRGLETFSQLVY-QD 182
Query: 261 DFRELRINSTDIYDYPRYAHRGLLLDTSRHYLSLSKILKNIDAMAANKMNVLHWHIVDDQ 440
+ IN + I D PR++HRG+L+DTSRHYL + ILK +DAMA NK NVLHWHIVDDQ
Sbjct: 183 SYGTFTINESTIIDSPRFSHRGILIDTSRHYLPVKIILKTLDAMAFNKFNVLHWHIVDDQ 242
Query: 441 SFPYHSEKFPELSRLGAY 494
SFPY S FPELS G+Y
Sbjct: 243 SFPYQSITFPELSNKGSY 260
>S62076-1|AAD13932.1| 529|Homo sapiens HEXA protein.
Length = 529
Score = 138 bits (335), Expect = 8e-33
Identities = 67/131 (51%), Positives = 84/131 (64%), Gaps = 1/131 (0%)
Frame = +3
Query: 111 LTAPCEKLPYFGMDESYNLXXXXXX-XXXXXXIWGVIRGLETWSQLFYLTNDFRELRINS 287
+T C +LP E+Y L +WG +RGLET+SQL + + + IN
Sbjct: 100 VTPGCNQLPTLESVENYTLTINDDQCLLLSETVWGALRGLETFSQLVWKSAE-GTFFINK 158
Query: 288 TDIYDYPRYAHRGLLLDTSRHYLSLSKILKNIDAMAANKMNVLHWHIVDDQSFPYHSEKF 467
T+I D+PR+ HRGLLLDTSRHYL LS IL +D MA NK+NV HWH+VDD SFPY S F
Sbjct: 159 TEIEDFPRFPHRGLLLDTSRHYLPLSSILDTLDVMAYNKLNVFHWHLVDDPSFPYESFTF 218
Query: 468 PELSRLGAYHP 500
PEL R G+Y+P
Sbjct: 219 PELMRKGSYNP 229
>M16424-1|AAB00965.1| 529|Homo sapiens HEXA protein.
Length = 529
Score = 138 bits (335), Expect = 8e-33
Identities = 67/131 (51%), Positives = 84/131 (64%), Gaps = 1/131 (0%)
Frame = +3
Query: 111 LTAPCEKLPYFGMDESYNLXXXXXX-XXXXXXIWGVIRGLETWSQLFYLTNDFRELRINS 287
+T C +LP E+Y L +WG +RGLET+SQL + + + IN
Sbjct: 100 VTPGCNQLPTLESVENYTLTINDDQCLLLSETVWGALRGLETFSQLVWKSAE-GTFFINK 158
Query: 288 TDIYDYPRYAHRGLLLDTSRHYLSLSKILKNIDAMAANKMNVLHWHIVDDQSFPYHSEKF 467
T+I D+PR+ HRGLLLDTSRHYL LS IL +D MA NK+NV HWH+VDD SFPY S F
Sbjct: 159 TEIEDFPRFPHRGLLLDTSRHYLPLSSILDTLDVMAYNKLNVFHWHLVDDPSFPYESFTF 218
Query: 468 PELSRLGAYHP 500
PEL R G+Y+P
Sbjct: 219 PELMRKGSYNP 229
>M13520-1|AAA51827.1| 490|Homo sapiens HEXA protein.
Length = 490
Score = 138 bits (335), Expect = 8e-33
Identities = 67/131 (51%), Positives = 84/131 (64%), Gaps = 1/131 (0%)
Frame = +3
Query: 111 LTAPCEKLPYFGMDESYNLXXXXXX-XXXXXXIWGVIRGLETWSQLFYLTNDFRELRINS 287
+T C +LP E+Y L +WG +RGLET+SQL + + + IN
Sbjct: 61 VTPGCNQLPTLESVENYTLTINDDQCLLLSETVWGALRGLETFSQLVWKSAE-GTFFINK 119
Query: 288 TDIYDYPRYAHRGLLLDTSRHYLSLSKILKNIDAMAANKMNVLHWHIVDDQSFPYHSEKF 467
T+I D+PR+ HRGLLLDTSRHYL LS IL +D MA NK+NV HWH+VDD SFPY S F
Sbjct: 120 TEIEDFPRFPHRGLLLDTSRHYLPLSSILDTLDVMAYNKLNVFHWHLVDDPSFPYESFTF 179
Query: 468 PELSRLGAYHP 500
PEL R G+Y+P
Sbjct: 180 PELMRKGSYNP 190
>BC084537-1|AAH84537.1| 529|Homo sapiens hexosaminidase A (alpha
polypeptide) protein.
Length = 529
Score = 138 bits (335), Expect = 8e-33
Identities = 67/131 (51%), Positives = 84/131 (64%), Gaps = 1/131 (0%)
Frame = +3
Query: 111 LTAPCEKLPYFGMDESYNLXXXXXX-XXXXXXIWGVIRGLETWSQLFYLTNDFRELRINS 287
+T C +LP E+Y L +WG +RGLET+SQL + + + IN
Sbjct: 100 VTPGCNQLPTLESVENYTLTINDDQCLLLSETVWGALRGLETFSQLVWKSAE-GTFFINK 158
Query: 288 TDIYDYPRYAHRGLLLDTSRHYLSLSKILKNIDAMAANKMNVLHWHIVDDQSFPYHSEKF 467
T+I D+PR+ HRGLLLDTSRHYL LS IL +D MA NK+NV HWH+VDD SFPY S F
Sbjct: 159 TEIEDFPRFPHRGLLLDTSRHYLPLSSILDTLDVMAYNKLNVFHWHLVDDPSFPYESFTF 218
Query: 468 PELSRLGAYHP 500
PEL R G+Y+P
Sbjct: 219 PELMRKGSYNP 229
>BC018927-1|AAH18927.1| 529|Homo sapiens hexosaminidase A (alpha
polypeptide) protein.
Length = 529
Score = 138 bits (335), Expect = 8e-33
Identities = 67/131 (51%), Positives = 84/131 (64%), Gaps = 1/131 (0%)
Frame = +3
Query: 111 LTAPCEKLPYFGMDESYNLXXXXXX-XXXXXXIWGVIRGLETWSQLFYLTNDFRELRINS 287
+T C +LP E+Y L +WG +RGLET+SQL + + + IN
Sbjct: 100 VTPGCNQLPTLESVENYTLTINDDQCLLLSETVWGALRGLETFSQLVWKSAE-GTFFINK 158
Query: 288 TDIYDYPRYAHRGLLLDTSRHYLSLSKILKNIDAMAANKMNVLHWHIVDDQSFPYHSEKF 467
T+I D+PR+ HRGLLLDTSRHYL LS IL +D MA NK+NV HWH+VDD SFPY S F
Sbjct: 159 TEIEDFPRFPHRGLLLDTSRHYLPLSSILDTLDVMAYNKLNVFHWHLVDDPSFPYESFTF 218
Query: 468 PELSRLGAYHP 500
PEL R G+Y+P
Sbjct: 219 PELMRKGSYNP 229
>AK222502-1|BAD96222.1| 529|Homo sapiens hexosaminidase A
preproprotein variant protein.
Length = 529
Score = 138 bits (335), Expect = 8e-33
Identities = 67/131 (51%), Positives = 84/131 (64%), Gaps = 1/131 (0%)
Frame = +3
Query: 111 LTAPCEKLPYFGMDESYNLXXXXXX-XXXXXXIWGVIRGLETWSQLFYLTNDFRELRINS 287
+T C +LP E+Y L +WG +RGLET+SQL + + + IN
Sbjct: 100 VTPGCNQLPTLESVENYTLTINDDQCLLLSETVWGALRGLETFSQLVWKSAE-GTFFINK 158
Query: 288 TDIYDYPRYAHRGLLLDTSRHYLSLSKILKNIDAMAANKMNVLHWHIVDDQSFPYHSEKF 467
T+I D+PR+ HRGLLLDTSRHYL LS IL +D MA NK+NV HWH+VDD SFPY S F
Sbjct: 159 TEIEDFPRFPHRGLLLDTSRHYLPLSSILDTLDVMAYNKLNVFHWHLVDDPSFPYESFTF 218
Query: 468 PELSRLGAYHP 500
PEL R G+Y+P
Sbjct: 219 PELMRKGSYNP 229
>BC001138-1|AAH01138.2| 409|Homo sapiens HEXA protein protein.
Length = 409
Score = 133 bits (322), Expect = 3e-31
Identities = 60/99 (60%), Positives = 74/99 (74%)
Frame = +3
Query: 204 IWGVIRGLETWSQLFYLTNDFRELRINSTDIYDYPRYAHRGLLLDTSRHYLSLSKILKNI 383
+WG +RGLET+SQL + + + IN T+I D+PR+ HRGLLLDTSRHYL LS IL +
Sbjct: 12 VWGALRGLETFSQLVWKSAE-GTFFINKTEIEDFPRFPHRGLLLDTSRHYLPLSSILDTL 70
Query: 384 DAMAANKMNVLHWHIVDDQSFPYHSEKFPELSRLGAYHP 500
D MA NK+NV HWH+VDD SFPY S FPEL R G+Y+P
Sbjct: 71 DVMAYNKLNVFHWHLVDDPSFPYESFTFPELMRKGSYNP 109
>M34906-1|AAA51829.1| 58|Homo sapiens beta-hexosaminidase
beta-subunit protein.
Length = 58
Score = 62.9 bits (146), Expect = 6e-10
Identities = 27/35 (77%), Positives = 28/35 (80%)
Frame = +3
Query: 390 MAANKMNVLHWHIVDDQSFPYHSEKFPELSRLGAY 494
MA NK NVLHWHIVDDQSFPY S FPELS G+Y
Sbjct: 1 MAFNKFNVLHWHIVDDQSFPYQSITFPELSNKGSY 35
>AY643499-1|AAV48875.1| 331|Homo sapiens ENC-1AS protein.
Length = 331
Score = 62.9 bits (146), Expect = 6e-10
Identities = 27/35 (77%), Positives = 28/35 (80%)
Frame = +3
Query: 390 MAANKMNVLHWHIVDDQSFPYHSEKFPELSRLGAY 494
MA NK NVLHWHIVDDQSFPY S FPELS G+Y
Sbjct: 1 MAFNKFNVLHWHIVDDQSFPYQSITFPELSNKGSY 35
Database: human
Posted date: Oct 23, 2007 1:18 PM
Number of letters in database: 76,859,062
Number of sequences in database: 237,096
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 69,820,036
Number of Sequences: 237096
Number of extensions: 1326891
Number of successful extensions: 2782
Number of sequences better than 10.0: 15
Number of HSP's better than 10.0 without gapping: 2688
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 2769
length of database: 76,859,062
effective HSP length: 85
effective length of database: 56,705,902
effective search space used: 4649883964
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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