Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= I10A02NGRL0002_B18
(554 letters)
Database: human
237,096 sequences; 76,859,062 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
AL583862-8|CAI14893.1| 247|Homo sapiens hydroxypyruvate isomera... 121 1e-27
AY775560-1|AAV84474.1| 229|Homo sapiens endothelial cell apopto... 119 6e-27
BC019041-1|AAH19041.1| 174|Homo sapiens HYI protein protein. 69 1e-11
BC006140-1|AAH06140.1| 217|Homo sapiens HYI protein protein. 69 1e-11
AL583862-5|CAI14890.1| 204|Homo sapiens hydroxypyruvate isomera... 69 1e-11
AF284751-1|AAG59853.1| 174|Homo sapiens HT036 protein. 69 1e-11
AF284750-1|AAG59852.1| 204|Homo sapiens HT036-ISO protein. 69 1e-11
AL583862-7|CAI14892.1| 165|Homo sapiens hydroxypyruvate isomera... 51 3e-06
AL583862-4|CAI14889.1| 180|Homo sapiens hydroxypyruvate isomera... 45 2e-04
AL583862-6|CAI14891.1| 229|Homo sapiens hydroxypyruvate isomera... 44 4e-04
>AL583862-8|CAI14893.1| 247|Homo sapiens hydroxypyruvate isomerase
homolog (E. coli) protein.
Length = 247
Score = 121 bits (292), Expect = 1e-27
Identities = 68/176 (38%), Positives = 103/176 (58%), Gaps = 7/176 (3%)
Frame = +1
Query: 46 MKFCANLSFMFAEASSILERYALARDAGFKAVESGFPFGCTLEQVKQAKENAGVEQVCIN 225
++F ANLS++F E S + R A +GF+AVE +P+ T E + +A AG+ V IN
Sbjct: 4 LRFSANLSWLFPELSGLPARVRAAGSSGFEAVEVAWPYAETPEALARAAREAGLRLVLIN 63
Query: 226 LKTGDTTKGEVGVTSVPGKENEFKDNLKTTIDYAKAVNARKIHIMAGIVDKPTPK----- 390
GD KGE+G+ +VPG++ F++ L+ + YAKA+ +IH+MAG V + +
Sbjct: 64 TPPGDQEKGEMGLGAVPGRQAAFREGLEQAVRYAKALGCPRIHLMAGRVPQGADRIAVKA 123
Query: 391 HWE-TFESNLKYAVDVLQGESLLGLIEPIN-QYSMPNYFLSDYGRAFGILDRINSP 552
E F NL++A VL E L+GL+EPIN + + P YFL +A IL ++ P
Sbjct: 124 EMEAVFLENLRHAAGVLAQEDLVGLLEPINTRITDPQYFLDTPQQAAAILQKVGRP 179
>AY775560-1|AAV84474.1| 229|Homo sapiens endothelial cell apoptosis
protein E-CE1 protein.
Length = 229
Score = 119 bits (287), Expect = 6e-27
Identities = 67/176 (38%), Positives = 102/176 (57%), Gaps = 7/176 (3%)
Frame = +1
Query: 46 MKFCANLSFMFAEASSILERYALARDAGFKAVESGFPFGCTLEQVKQAKENAGVEQVCIN 225
++F ANLS++F E + R A +GF+AVE +P+ T E + +A AG+ V IN
Sbjct: 4 LRFSANLSWLFPELPGLPARVRAAGSSGFEAVEVAWPYAETPEALARAAREAGLRLVLIN 63
Query: 226 LKTGDTTKGEVGVTSVPGKENEFKDNLKTTIDYAKAVNARKIHIMAGIVDKPTPK----- 390
GD KGE+G+ +VPG++ F++ L+ + YAKA+ +IH+MAG V + +
Sbjct: 64 TPPGDQEKGEMGLGAVPGRQAAFREGLEQAVRYAKALGCPRIHLMAGRVPQGADRIAVKA 123
Query: 391 HWE-TFESNLKYAVDVLQGESLLGLIEPIN-QYSMPNYFLSDYGRAFGILDRINSP 552
E F NL++A VL E L+GL+EPIN + + P YFL +A IL ++ P
Sbjct: 124 EMEAVFLENLRHAAGVLAQEDLVGLLEPINTRITDPQYFLDTPQQAAAILQKVGRP 179
>BC019041-1|AAH19041.1| 174|Homo sapiens HYI protein protein.
Length = 174
Score = 68.5 bits (160), Expect = 1e-11
Identities = 39/106 (36%), Positives = 62/106 (58%), Gaps = 7/106 (6%)
Frame = +1
Query: 256 VGVTSVPGKENEFKDNLKTTIDYAKAVNARKIHIMAGIVDKPTPK-----HWE-TFESNL 417
+G+ +VPG++ F++ L+ + YAKA+ +IH+MAG V + + E F NL
Sbjct: 1 MGLGAVPGRQAAFREGLEQAVRYAKALGCPRIHLMAGRVPQGADRIAVKAEMEAVFLENL 60
Query: 418 KYAVDVLQGESLLGLIEPIN-QYSMPNYFLSDYGRAFGILDRINSP 552
++A VL E L+GL+EPIN + + P YFL +A IL ++ P
Sbjct: 61 RHAAGVLAQEDLVGLLEPINTRITDPQYFLDTPQQAAAILQKVGRP 106
>BC006140-1|AAH06140.1| 217|Homo sapiens HYI protein protein.
Length = 217
Score = 68.5 bits (160), Expect = 1e-11
Identities = 39/106 (36%), Positives = 62/106 (58%), Gaps = 7/106 (6%)
Frame = +1
Query: 256 VGVTSVPGKENEFKDNLKTTIDYAKAVNARKIHIMAGIVDKPTPK-----HWE-TFESNL 417
+G+ +VPG++ F++ L+ + YAKA+ +IH+MAG V + + E F NL
Sbjct: 1 MGLGAVPGRQAAFREGLEQAVRYAKALGCPRIHLMAGRVPQGADRIAVKAEMEAVFLENL 60
Query: 418 KYAVDVLQGESLLGLIEPIN-QYSMPNYFLSDYGRAFGILDRINSP 552
++A VL E L+GL+EPIN + + P YFL +A IL ++ P
Sbjct: 61 RHAAGVLAQEDLVGLLEPINTRITDPQYFLDTPQQAAAILQKVGRP 106
>AL583862-5|CAI14890.1| 204|Homo sapiens hydroxypyruvate isomerase
homolog (E. coli) protein.
Length = 204
Score = 68.5 bits (160), Expect = 1e-11
Identities = 39/106 (36%), Positives = 62/106 (58%), Gaps = 7/106 (6%)
Frame = +1
Query: 256 VGVTSVPGKENEFKDNLKTTIDYAKAVNARKIHIMAGIVDKPTPK-----HWE-TFESNL 417
+G+ +VPG++ F++ L+ + YAKA+ +IH+MAG V + + E F NL
Sbjct: 1 MGLGAVPGRQAAFREGLEQAVRYAKALGCPRIHLMAGRVPQGADRIAVKAEMEAVFLENL 60
Query: 418 KYAVDVLQGESLLGLIEPIN-QYSMPNYFLSDYGRAFGILDRINSP 552
++A VL E L+GL+EPIN + + P YFL +A IL ++ P
Sbjct: 61 RHAAGVLAQEDLVGLLEPINTRITDPQYFLDTPQQAAAILQKVGRP 106
>AF284751-1|AAG59853.1| 174|Homo sapiens HT036 protein.
Length = 174
Score = 68.5 bits (160), Expect = 1e-11
Identities = 39/106 (36%), Positives = 62/106 (58%), Gaps = 7/106 (6%)
Frame = +1
Query: 256 VGVTSVPGKENEFKDNLKTTIDYAKAVNARKIHIMAGIVDKPTPK-----HWE-TFESNL 417
+G+ +VPG++ F++ L+ + YAKA+ +IH+MAG V + + E F NL
Sbjct: 1 MGLGAVPGRQAAFREGLEQAVRYAKALGCPRIHLMAGRVPQGADRIAVKAEMEAVFLENL 60
Query: 418 KYAVDVLQGESLLGLIEPIN-QYSMPNYFLSDYGRAFGILDRINSP 552
++A VL E L+GL+EPIN + + P YFL +A IL ++ P
Sbjct: 61 RHAAGVLAQEDLVGLLEPINTRITDPQYFLDTPQQAAAILQKVGRP 106
>AF284750-1|AAG59852.1| 204|Homo sapiens HT036-ISO protein.
Length = 204
Score = 68.5 bits (160), Expect = 1e-11
Identities = 39/106 (36%), Positives = 62/106 (58%), Gaps = 7/106 (6%)
Frame = +1
Query: 256 VGVTSVPGKENEFKDNLKTTIDYAKAVNARKIHIMAGIVDKPTPK-----HWE-TFESNL 417
+G+ +VPG++ F++ L+ + YAKA+ +IH+MAG V + + E F NL
Sbjct: 1 MGLGAVPGRQAAFREGLEQAVRYAKALGCPRIHLMAGRVPQGADRIAVKAEMEAVFLENL 60
Query: 418 KYAVDVLQGESLLGLIEPIN-QYSMPNYFLSDYGRAFGILDRINSP 552
++A VL E L+GL+EPIN + + P YFL +A IL ++ P
Sbjct: 61 RHAAGVLAQEDLVGLLEPINTRITDPQYFLDTPQQAAAILQKVGRP 106
>AL583862-7|CAI14892.1| 165|Homo sapiens hydroxypyruvate isomerase
homolog (E. coli) protein.
Length = 165
Score = 50.8 bits (116), Expect = 3e-06
Identities = 35/106 (33%), Positives = 57/106 (53%), Gaps = 7/106 (6%)
Frame = +1
Query: 256 VGVTSVPGKENEFKDNLKTTIDYAKAVNARKIHIMAGIVDKPTPK-----HWET-FESNL 417
+G+ +VPG++ F++ L+ + +IH+MAG V + + E F NL
Sbjct: 1 MGLGAVPGRQAAFREGLEQAV---------RIHLMAGRVPQGADRIAVKAEMEAVFLENL 51
Query: 418 KYAVDVLQGESLLGLIEPIN-QYSMPNYFLSDYGRAFGILDRINSP 552
++A VL E L+GL+EPIN + + P YFL +A IL ++ P
Sbjct: 52 RHAAGVLAQEDLVGLLEPINTRITDPQYFLDTPQQAAAILQKVGRP 97
>AL583862-4|CAI14889.1| 180|Homo sapiens hydroxypyruvate isomerase
homolog (E. coli) protein.
Length = 180
Score = 44.8 bits (101), Expect = 2e-04
Identities = 29/76 (38%), Positives = 42/76 (55%), Gaps = 7/76 (9%)
Frame = +1
Query: 346 KIHIMAGIVDKPTPK-----HWET-FESNLKYAVDVLQGESLLGLIEPIN-QYSMPNYFL 504
+IH+MAG V + + E F NL++A VL E L+GL+EPIN + + P YFL
Sbjct: 37 RIHLMAGRVPQGADRIAVKAEMEAVFLENLRHAAGVLAQEDLVGLLEPINTRITDPQYFL 96
Query: 505 SDYGRAFGILDRINSP 552
+A IL ++ P
Sbjct: 97 DTPQQAAAILQKVGRP 112
>AL583862-6|CAI14891.1| 229|Homo sapiens hydroxypyruvate isomerase
homolog (E. coli) protein.
Length = 229
Score = 44.0 bits (99), Expect = 4e-04
Identities = 29/75 (38%), Positives = 41/75 (54%), Gaps = 7/75 (9%)
Frame = +1
Query: 349 IHIMAGIVDKPTPK-----HWET-FESNLKYAVDVLQGESLLGLIEPIN-QYSMPNYFLS 507
IH+MAG V + + E F NL++A VL E L+GL+EPIN + + P YFL
Sbjct: 57 IHLMAGRVPQGADRIAVKAEMEAVFLENLRHAAGVLAQEDLVGLLEPINTRITDPQYFLD 116
Query: 508 DYGRAFGILDRINSP 552
+A IL ++ P
Sbjct: 117 TPQQAAAILQKVGRP 131
Database: human
Posted date: Oct 23, 2007 1:18 PM
Number of letters in database: 76,859,062
Number of sequences in database: 237,096
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 73,728,289
Number of Sequences: 237096
Number of extensions: 1473297
Number of successful extensions: 3286
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 3178
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 3277
length of database: 76,859,062
effective HSP length: 86
effective length of database: 56,468,806
effective search space used: 5533942988
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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