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Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= I10A02NGRL0002_B02
         (572 letters)

Database: human 
           237,096 sequences; 76,859,062 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

AJ007714-1|CAA07619.2|  926|Homo sapiens lysine-ketoglutarate re...   225   1e-58
AF229180-1|AAF44328.1|  926|Homo sapiens alpha-aminoadipate semi...   225   1e-58
AC006020-2|AAF03526.1|  926|Homo sapiens lysine ketoglutarate re...   225   1e-58
BT009807-1|AAP88809.1|  568|Homo sapiens numb homolog (Drosophil...    33   0.71 
AF015041-1|AAD01549.1|  609|Homo sapiens NUMB-R protein protein.       33   0.71 

>AJ007714-1|CAA07619.2|  926|Homo sapiens lysine-ketoglutarate
           reductase /saccharopine dehydrogenase protein.
          Length = 926

 Score =  225 bits (549), Expect = 1e-58
 Identities = 104/176 (59%), Positives = 133/176 (75%), Gaps = 1/176 (0%)
 Frame = +2

Query: 2   DHEEYEEHPERYISTFAQKIAPYTSVLVNCIYWAVESPKLLTIPDAKHLLLPSHTPWLPR 181
           D  EY++HPERYIS F   IAPYT+ L+N IYW   +P+LLT  DA+ LL P    + P 
Sbjct: 280 DPAEYDKHPERYISRFNTDIAPYTTCLINGIYWEQNTPRLLTRQDAQSLLAPGK--FSPA 337

Query: 182 SI-GAPALPHRMLAICDISADPGGSIEFMNECTTIDTPFCLYDADRNKDTKSFKGPGVLV 358
            + G PALPH+++AICDISAD GGSIEFM ECTTI+ PFC+YDAD++    S +G G+L+
Sbjct: 338 GVEGCPALPHKLVAICDISADTGGSIEFMTECTTIEHPFCMYDADQHIIHDSVEGSGILM 397

Query: 359 CSIDNMPTQLPREATDFFGDLLFPYAEDIMSSDATKPLEDHNFTSVVHGAIITSNG 526
           CSIDN+P QLP EAT+ FGD+L+PY E+++ SDAT+PLE  NF+ VV  A+ITSNG
Sbjct: 398 CSIDNLPAQLPIEATECFGDMLYPYVEEMILSDATQPLESQNFSPVVRDAVITSNG 453


>AF229180-1|AAF44328.1|  926|Homo sapiens alpha-aminoadipate
           semialdehyde synthase protein.
          Length = 926

 Score =  225 bits (549), Expect = 1e-58
 Identities = 104/176 (59%), Positives = 133/176 (75%), Gaps = 1/176 (0%)
 Frame = +2

Query: 2   DHEEYEEHPERYISTFAQKIAPYTSVLVNCIYWAVESPKLLTIPDAKHLLLPSHTPWLPR 181
           D  EY++HPERYIS F   IAPYT+ L+N IYW   +P+LLT  DA+ LL P    + P 
Sbjct: 280 DPAEYDKHPERYISRFNTDIAPYTTCLINGIYWEQNTPRLLTRQDAQSLLAPGK--FSPA 337

Query: 182 SI-GAPALPHRMLAICDISADPGGSIEFMNECTTIDTPFCLYDADRNKDTKSFKGPGVLV 358
            + G PALPH+++AICDISAD GGSIEFM ECTTI+ PFC+YDAD++    S +G G+L+
Sbjct: 338 GVEGCPALPHKLVAICDISADTGGSIEFMTECTTIEHPFCMYDADQHIIHDSVEGSGILM 397

Query: 359 CSIDNMPTQLPREATDFFGDLLFPYAEDIMSSDATKPLEDHNFTSVVHGAIITSNG 526
           CSIDN+P QLP EAT+ FGD+L+PY E+++ SDAT+PLE  NF+ VV  A+ITSNG
Sbjct: 398 CSIDNLPAQLPIEATECFGDMLYPYVEEMILSDATQPLESQNFSPVVRDAVITSNG 453


>AC006020-2|AAF03526.1|  926|Homo sapiens lysine ketoglutarate
           reductase/saccharopine dehydrogenase protein.
          Length = 926

 Score =  225 bits (549), Expect = 1e-58
 Identities = 104/176 (59%), Positives = 133/176 (75%), Gaps = 1/176 (0%)
 Frame = +2

Query: 2   DHEEYEEHPERYISTFAQKIAPYTSVLVNCIYWAVESPKLLTIPDAKHLLLPSHTPWLPR 181
           D  EY++HPERYIS F   IAPYT+ L+N IYW   +P+LLT  DA+ LL P    + P 
Sbjct: 280 DPAEYDKHPERYISRFNTDIAPYTTCLINGIYWEQNTPRLLTRQDAQSLLAPGK--FSPA 337

Query: 182 SI-GAPALPHRMLAICDISADPGGSIEFMNECTTIDTPFCLYDADRNKDTKSFKGPGVLV 358
            + G PALPH+++AICDISAD GGSIEFM ECTTI+ PFC+YDAD++    S +G G+L+
Sbjct: 338 GVEGCPALPHKLVAICDISADTGGSIEFMTECTTIEHPFCMYDADQHIIHDSVEGSGILM 397

Query: 359 CSIDNMPTQLPREATDFFGDLLFPYAEDIMSSDATKPLEDHNFTSVVHGAIITSNG 526
           CSIDN+P QLP EAT+ FGD+L+PY E+++ SDAT+PLE  NF+ VV  A+ITSNG
Sbjct: 398 CSIDNLPAQLPIEATECFGDMLYPYVEEMILSDATQPLESQNFSPVVRDAVITSNG 453


>BT009807-1|AAP88809.1|  568|Homo sapiens numb homolog
           (Drosophila)-like protein.
          Length = 568

 Score = 33.1 bits (72), Expect = 0.71
 Identities = 25/100 (25%), Positives = 43/100 (43%)
 Frame = -3

Query: 504 PCTTEVKL*SSKGLVASELIISSA*GKRRSPKKSVASRGSCVGMLSIEHTNTPGPLKLLV 325
           P TT        G   +    ++A  +R +P + +  +GS  G  ++   N+P   +L +
Sbjct: 225 PATTSPGEKGEAGTPVAAGTTAAAIPRRHAPLEQLVRQGSFRGFPALSQKNSPFKRQLSL 284

Query: 324 SLFLSAS*RQKGVSIVVHSFMNSIEPPGSADMSQIASILC 205
            L    S  Q+     V   +  +EPPG+ D   I + LC
Sbjct: 285 RLNELPSTLQRRTDFQVKGTVPEMEPPGAGDSDSI-NALC 323


>AF015041-1|AAD01549.1|  609|Homo sapiens NUMB-R protein protein.
          Length = 609

 Score = 33.1 bits (72), Expect = 0.71
 Identities = 25/100 (25%), Positives = 43/100 (43%)
 Frame = -3

Query: 504 PCTTEVKL*SSKGLVASELIISSA*GKRRSPKKSVASRGSCVGMLSIEHTNTPGPLKLLV 325
           P TT        G   +    ++A  +R +P + +  +GS  G  ++   N+P   +L +
Sbjct: 266 PATTSPGEKGEAGTPVAAGTTAAAIPRRHAPLEQLVRQGSFRGFPALSQKNSPFKRQLSL 325

Query: 324 SLFLSAS*RQKGVSIVVHSFMNSIEPPGSADMSQIASILC 205
            L    S  Q+     V   +  +EPPG+ D   I + LC
Sbjct: 326 RLNELPSTLQRRTDFQVKGTVPEMEPPGAGDSDSI-NALC 364


  Database: human
    Posted date:  Oct 23, 2007  1:18 PM
  Number of letters in database: 76,859,062
  Number of sequences in database:  237,096
  
Lambda     K      H
   0.318    0.134    0.401 

Gapped
Lambda     K      H
   0.279   0.0580    0.190 


Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 90,003,944
Number of Sequences: 237096
Number of extensions: 1972970
Number of successful extensions: 4570
Number of sequences better than 10.0: 5
Number of HSP's better than 10.0 without gapping: 4348
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 4564
length of database: 76,859,062
effective HSP length: 86
effective length of database: 56,468,806
effective search space used: 5872755824
frameshift window, decay const: 40,  0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)

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